WorldWideScience

Sample records for extend hose life

  1. Evaluation of Hose in Hose Transfer Line Service Life for Hanford's Interim Stabilization Program

    International Nuclear Information System (INIS)

    TORRES, T.D.

    2000-01-01

    RPP-6153, Engineering Task Plan for Hose-in-Hose Transfer System for the Interim Stabilization Program, defines the programmatic goals, functional requirements, and technical criteria for the development and subsequent installation of transfer line equipment to support Hanford's Interim Stabilization Program. RPP-6028, Specification for Hose in Hose Transfer Lines for Hanford's Interim Stabilization Program, has been issued to define the specific requirements for the design, manufacture, and verification of transfer line assemblies for specific waste transfer applications. Included in RPP-6028 are tables defining the chemical constituents of concern to which transfer lines will be exposed. Current Interim Stabilization Program planning forecasts that the at-grade transfer lines will be required to convey pumpable waste for as much as three years after commissioning. Prudent engineering dictates that the equipment placed in service have a working life in excess of this forecasted time period, with some margin to allow for future adjustments to the planned schedule. This document evaluates the effective service life of the Hose-in-Hose Transfer Lines, based on information submitted by the manufacturer and published literature. The effective service life of transfer line assemblies is a function of several factors. Foremost among these are process fluid characteristics, ambient environmental conditions, and the manufacturer's stated shelf life. This evaluation examines the manufacturer's certification of shelf life, the manufacturer's certifications of chemical compatibility with waste, and published literature on the effects of exposure to ionizing radiation on the mechanical properties of elastomeric materials to evaluate transfer line service life

  2. Evaluation of Hose in Hose Transfer Line Service Life for Hanfords Interim Stabilization Program

    International Nuclear Information System (INIS)

    TORRES, T.D.

    2001-01-01

    RPP-6153, Engineering Task Plan for Hose-in-Hose Transfer System for the Interim Stabilization Program (Torres, 2000a), defines the programmatic goals, functional requirements, and technical criteria for the development and subsequent installation of waste transfer line equipment to support Hanford's Interim Stabilization Program. RPP-6028, Specification for Hose in Hose Transfer Lines for Hanford's Interim Stabilization Program (Torres, 2000b), has been issued to define the specific requirements for the design, manufacture, and verification of transfer line assemblies for specific waste transfer applications associated with Interim Stabilization. Included in RPP-6028 are tables defining the chemical constituents of concern to which transfer lines will be exposed. Current Interim Stabilization Program planning forecasts that the at-grade transfer lines will be required to convey pumpable waste for as much as three years after commissioning, RPP-6028 Section 3.2.7. Performance Incentive Number ORP-05 requires that all the Single Shell Tanks be Interim Stabilized by September 30, 2003. The Tri-Party Agreement (TPA) milestone M-41-00, enforced by a federal consent decree, requires all the Single Shell Tanks to be Interim stabilized by September 30, 2004. By meeting the Performance Incentive the TPA milestone is met. Prudent engineering dictates that the equipment used to transfer waste have a life in excess of the forecasted operational time period, with some margin to allow for future adjustments to the planned schedule. This document evaluates the effective service life of the Hose-in-Hose Transfer Lines, based on information submitted by the manufacturer, published literature and calculations. The effective service life of transfer line assemblies is a function of several factors. Foremost among these are the hose material's resistance to the harmful effects of process fluid characteristics, ambient environmental conditions, exposure to ionizing radiation and the

  3. Evaluation of Hose in Hose Transfer Line Service Life for Hanford's Interim Stabilization Program

    Energy Technology Data Exchange (ETDEWEB)

    TORRES, T.D.

    2000-08-24

    RPP-6153, Engineering Task Plan for Hose-in-Hose Transfer System for the Interim Stabilization Program, defines the programmatic goals, functional requirements, and technical criteria for the development and subsequent installation of transfer line equipment to support Hanford's Interim Stabilization Program. RPP-6028, Specification for Hose in Hose Transfer Lines for Hanford's Interim Stabilization Program, has been issued to define the specific requirements for the design, manufacture, and verification of transfer line assemblies for specific waste transfer applications. Included in RPP-6028 are tables defining the chemical constituents of concern to which transfer lines will be exposed. Current Interim Stabilization Program planning forecasts that the at-grade transfer lines will be required to convey pumpable waste for as much as three years after commissioning. Prudent engineering dictates that the equipment placed in service have a working life in excess of this forecasted time period, with some margin to allow for future adjustments to the planned schedule. This document evaluates the effective service life of the Hose-in-Hose Transfer Lines, based on information submitted by the manufacturer and published literature. The effective service life of transfer line assemblies is a function of several factors. Foremost among these are process fluid characteristics, ambient environmental conditions, and the manufacturer's stated shelf life. This evaluation examines the manufacturer's certification of shelf life, the manufacturer's certifications of chemical compatibility with waste, and published literature on the effects of exposure to ionizing radiation on the mechanical properties of elastomeric materials to evaluate transfer line service life.

  4. Extended Life Coolant Testing

    Science.gov (United States)

    2016-06-06

    military vehicles. Newer vehicles come factory- filled with ELC, while the Army continues to use traditional supplemental coolant additives (SCA)-based...UNCLASSIFIED TABLE OF CONTENTS EXTENDED LIFE COOLANT TESTING INTERIM REPORT TFLRF No. 478 by Gregory A. T. Hansen Edwin A...longer needed. Do not return it to the originator. UNCLASSIFIED UNCLASSIFIED EXTENDED LIFE COOLANT TESTING INTERIM REPORT TFLRF No

  5. Extending mine life

    International Nuclear Information System (INIS)

    Anon.

    1984-01-01

    Mine layouts, new machines and techniques, research into problem areas of ground control and so on, are highlighted in this report on extending mine life. The main resources taken into account are coal mining, uranium mining, molybdenum and gold mining

  6. Extended mission life support systems

    Science.gov (United States)

    Quattrone, P. D.

    1985-01-01

    Extended manned space missions which include interplanetary missions require regenerative life support systems. Manned mission life support considerations are placed in perspective and previous manned space life support system technology, activities and accomplishments in current supporting research and technology (SR&T) programs are reviewed. The life support subsystem/system technologies required for an enhanced duration orbiter (EDO) and a space operations center (SOC), regenerative life support functions and technology required for manned interplanetary flight vehicles, and future development requirements are outlined. The Space Shuttle Orbiters (space transportation system) is space cabin atmosphere is maintained at Earth ambient pressure of 14.7 psia (20% O2 and 80% N2). The early Shuttle flights will be seven-day flights, and the life support system flight hardware will still utilize expendables.

  7. Physical activity extends life expectancy

    Science.gov (United States)

    Leisure-time physical activity is associated with longer life expectancy, even at relatively low levels of activity and regardless of body weight, according to a study by a team of researchers led by the NCI.

  8. NTRE extended life feasibility assessment

    Science.gov (United States)

    Results of a feasibility analysis of a long life, reusable nuclear thermal rocket engine are presented in text and graph form. Two engine/reactor concepts are addressed: the Particle Bed Reactor (PBR) design and the Commonwealth of Independent States (CIS) concept. Engine design, integration, reliability, and safety are addressed by various members of the NTRE team from Aerojet Propulsion Division, Energopool (Russia), and Babcock & Wilcox.

  9. Investigation of damaged hoses

    DEFF Research Database (Denmark)

    Voigt, Kristian

    1998-01-01

    Hoses used in hydraulics are known to fail. The total understanding of the failure mechanics doesn't seem to be known therefore a study is appropriate when a basis for a new product programme has to be set up.The approach in this task has been to look at different locations on a hose assembly where...... hoses fail and how it can be seen that the hose has failed. Some of reasons for the failures seem to be hypothesis rather than scientific evidence but it shows the authors best insight at the time of writing this text. The causes for failures has been grouped in two - the first being failures appearing...

  10. Extended Life Testing of Duplex Ball Bearings

    Science.gov (United States)

    Mobley, Jeffrey; Robertson, Michael; Hodges, Charles

    2016-01-01

    Sierra Nevada Corporation’s Space Systems performed bearing life testing for the Scan Mirror Motor/Encoder Assembly (SMMA), part of the Scan Mirror Assembly on-board the Aerosol Polarimetry Sensor (APS) on the NASA Glory Spacecraft. The baseline bearing life test duration extended beyond the launch date for the Glory Spacecraft; a risk that the program was willing to undertake with the understanding that if any anomalies or failures occurred before the required life was achieved, then the mission objectives or operating profile could be modified on orbit to take those results into account. Even though the Glory Spacecraft failed to reach orbit during its launch in March of 2011, the bearing life testing was continued through a mutual understanding of value between Sierra Nevada Corporation and our customer; with a revised goal of testing to failure rather than completing a required number of life cycles. Life testing thus far has not only exceeded the original mission required life, but has also exceeded the published test data for Cumulative Degradation Factor (CDF) from NASA/CR-2009-215681. Many lessons were learned along the way regarding long life testing. The bearing life test has been temporarily suspended due to test support equipment issues.

  11. Assessment of Refueling Hose Visibility

    Science.gov (United States)

    2012-10-01

    order to make inteligent decisions regarding hose replacement or hose cleaning one needs to look at the individual reflection coefficients not just... artificial lighting used to illuminate the hose does not satisfy the specular reflection geometry for the pilot’s view angle of the hose. Also, from

  12. Biofilms in shower hoses.

    Science.gov (United States)

    Proctor, Caitlin R; Reimann, Mauro; Vriens, Bas; Hammes, Frederik

    2017-12-14

    Shower hoses offer an excellent bacterial growth environment in close proximity to a critical end-user exposure route within building drinking water plumbing. However, the health risks associated with and processes underlying the development of biofilms in shower hoses are poorly studied. In a global survey, biofilms from 78 shower hoses from 11 countries were characterized in terms of cell concentration (4.1 × 10 4 -5.8 × 10 8  cells/cm 2 ), metal accumulation (including iron, lead, and copper), and microbiome composition (including presence of potential opportunistic pathogens). In countries using disinfectant, biofilms had on average lower cell concentrations and diversity. Metal accumulation (up to 5 μg-Fe/cm 2 , 75 ng-Pb/cm 2 , and 460 ng-Cu/cm 2 ) seemed to be partially responsible for discoloration in biofilms, and likely originated from other pipes upstream in the building. While some genera that may contain potential opportunistic pathogens (Legionella, detected in 21/78 shower hoses) were positively correlated with biofilm cell concentration, others (Mycobacterium, Pseudomonas) had surprisingly non-existent or negative correlations with biofilm cell concentrations. In a controlled study, 15 identical shower hoses were installed for the same time period in the same country, and both stagnant and flowing water samples were collected. Ecological theory of dispersal and selection helped to explain microbiome composition and diversity of different sample types. Shower hose age was related to metal accumulation but not biofilm cell concentration, while frequency of use appeared to influence biofilm cell concentration. This study shows that shower hose biofilms are clearly a critical element of building drinking water plumbing, and a potential target for building drinking water plumbing monitoring. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Conceptual Framework To Extend Life Cycle Assessment ...

    Science.gov (United States)

    Life Cycle Assessment (LCA) is a decision-making tool that accounts for multiple impacts across the life cycle of a product or service. This paper presents a conceptual framework to integrate human health impact assessment with risk screening approaches to extend LCA to include near-field chemical sources (e.g., those originating from consumer products and building materials) that have traditionally been excluded from LCA. A new generation of rapid human exposure modeling and high-throughput toxicity testing is transforming chemical risk prioritization and provides an opportunity for integration of screening-level risk assessment (RA) with LCA. The combined LCA and RA approach considers environmental impacts of products alongside risks to human health, which is consistent with regulatory frameworks addressing RA within a sustainability mindset. A case study is presented to juxtapose LCA and risk screening approaches for a chemical used in a consumer product. The case study demonstrates how these new risk screening tools can be used to inform toxicity impact estimates in LCA and highlights needs for future research. The framework provides a basis for developing tools and methods to support decision making on the use of chemicals in products. This paper presents a conceptual framework for including near-field exposures into Life Cycle Assessment using advanced human exposure modeling and high-throughput tools

  14. Extended life aluminide fuel. Final report

    International Nuclear Information System (INIS)

    Miller, L.G.; Beeston, J.M.

    1986-06-01

    As the price of fuel fabrication, shipment of both new and spent fuel, and fuel reprocessing continue to rise at a rapid rate, researchers look for alternate methods to keep reactor fuel costs within their limited funding. Extended fuel element lifetimes, without jeopardizing reactor safety, can reduce fuel costs by up to a factor of two. The Extended Life Aluminide (ELAF) program was started at the Idaho National Engineering Laboratory (INEL) as a joint project of the United States Department of Energy (DOE), the University of Missouri, and the Massachusetts Institute of Technology research reactors. Fuel plates of Advanced Test Reactor (ATR) type construction were fabricated at Atomics International and irradiated in the ATR at the INEL. Four fuel matrix compositions were tested (i.e., 50 vol% UAl/sub x/ cores for reference, and 40, 45 and 50 vol% UAl 2 cores). The 50 vol% UAl 2 cores contained up to 3 grams U-235 per cm 3 of core. Three plates of each composition were irradiated to peak burnup levels of 3 x 10 21 fission/cm 3 of core. The only observed damage was due to external corrosion at similar rates experienced by UAl/sub x/ fuel elements in test reactors

  15. Desirable design of hose fittings

    DEFF Research Database (Denmark)

    Voigt, Kristian

    1998-01-01

    This paper describes the primary functionality of a hose fitting. There has been made a discussion about the different parts of the hose assembly - the nipple, the hose and the outer compression parts. The last subject covered is which criteria should be put up for determining what is a good hose...... fittings. There has been made an uncompleted list of 'Voice of Customer' to this respect. Observations and interviews in industry should expand this list....

  16. Cost savings from extended life nuclear plants

    International Nuclear Information System (INIS)

    Forest, L.R. Jr.; Deutsch, T.R.; Schenler, W.W.

    1988-01-01

    The study assesses the costs and benefits of nuclear plant life extension (NUPLEX) for the United States of America as a whole under widely varying economic assumptions and for individual U.S. nuclear facilities under baseline assumptions. The study also presents a cost-benefit analysis of the nuclear industry's planned advanced light water reactor (ALWR). Under baseline economic assumptions and using U.S. average costs of fuel and of nonfuel operations and maintenance, it is found that NUPLEX saves future electricity users about 3 U.S. cents/kW·h (3.7 cents/kW·h versus 7.2 cents/kW·h) compared with new coal fired (NEWCOAL) plants, which are viewed as the most likely competing option to NUPLEX. Under optimistic assumptions the savings swell to almost 10 cents/kW·h. More notably, however, NUPLEX still saves money under unlikely pessimistic assumptions. While NUPLEX is probably advantageous for most existing U.S. nuclear facilities, it appears more so for some than others. Preliminary evidence indicates that PLEX refurbishment may cost somewhat less on average for PWRs than for BWRs and will almost certainly cost less for newer vintage plants than for older vintages. In addition, PLEX (avoided cost) benefits are especially great for those regions in which alternative coal fired power is comparatively expensive because of relatively high delivered coal prices. On the basis of these and other considerations, the authors developed a parametric method for ranking existing plants in terms of the relative attractiveness of NUPLEX. The ALWR program calls for a simple evolutionary redesign of LWRs, incorporating the lessons learned in building and operating the current generation of nuclear units. In accordance with the utility developmental goals on construction costs, operating performance, and service life, the ALWR offers power at a substantially lower cost than NEWCOAL plants. The assumptions of extended operating life contributes to the cost advantage. The

  17. Extending The Shelf Life Of Blood Platelets

    Science.gov (United States)

    Surgenor, Douglas M.

    1988-01-01

    New method of storing human blood platelets extends vitality for transfusions. Packaged as suspension in sterile liquid in plastic blood bags. Each bag placed between pair of plastic grids, and rubberbands placed around sandwich thus formed to hold together. Stored upright in open air or in container through which air pumped at rate of at least 45 L/min. Ensures that platelets receive ample oxygen and expiratory carbon dioxide form platelets removed before pH drops to harmful levels.

  18. Coatings Extend Life of Engines and Infrastructure

    Science.gov (United States)

    2010-01-01

    MesoCoat Inc., of Euclid, Ohio, collaborated with Glenn Research Center to provide thermal barrier coating (TBC) technology, developed by Glenn researcher Dongming Zhu, to enhance the lifespan and performance of engines in U.S. Air Force legacy aircraft. The TBC reduces thermal stresses on engine parts, increasing component life by 50 percent. MesoCoat is also producing metal cladding technology that may soon provide similar life-lengthening benefits for the Nation's infrastructure. Through a Space Act Agreement with Glenn, the company employs the Center's high-density infrared arc lamp system to bond its cladding materials for demonstration prototypes; the coating technology can prevent corrosion on metal beams, pipes, and rebar for up to 100 years.

  19. Extending Life Concepts to Complex Systems

    Directory of Open Access Journals (Sweden)

    Jean Le Fur

    2013-01-01

    Full Text Available There is still no consensus definition of complex systems. This article explores, as a heuristic approach, the possibility of using notions associated with life as transversal concepts for defining complex systems. This approach is developed within a general classification of systems, with complex systems considered as a general ‘living things’ category and living organisms as a specialised class within this category. Concepts associated with life are first explored in the context of complex systems: birth, death and lifetime, adaptation, ontogeny and growth, reproduction. Thereafter, a refutation approach is used to test the proposed classification against a set of diverse systems, including a reference case, edge cases and immaterial complex systems. The summary of this analysis is then used to generate a definition of complex systems, based on the proposal, and within the background of cybernetics, complex adaptive systems and biology. Using notions such as ‘birth’ or ‘lifespan’ as transversal concepts may be of heuristic value for the generic characterization of complex systems, opening up new lines of research for improving their definition.

  20. Cost savings from extended life nuclear plants

    International Nuclear Information System (INIS)

    Forest, L.R. Jr.; Deutsch, T.R.; Schenler, W.W.

    1988-09-01

    This study assesses the costs and benefits of nuclear power plant life extension (NUPLEX) for the overall US under widely varying economic assumptions and compares these with alternative new coal- fired plants (NEWCOAL). It is found that NUPLEX saves future electricity consumers more than 3 cents/-kwh compared with NEWCOAL. The NUPLEX costs and benefits for existing individual US nuclear power plants under base-line, or most likely, assumptions are assessed to determine the effects of the basic plant design and plant age. While benefits vary widely, virtually all units would have a positive benefit from NUPLEX. The study also presents a cost-benefit analysis of the nuclear industry's planned advanced light water reactor (ALWR). It is concluded that ALWR offers electrical power at a substantially lower cost than NEWCOAL. 9 refs., 6 figs

  1. Exploring reflective learning during the extended consumption of life experiences

    OpenAIRE

    Bosangit, Carmela; Demangeot, Catherine

    2016-01-01

    Purpose\\ud \\ud This study explores the potential for personal transformation resulting from reflective learning that occurs during the extended consumption of life experiences. Extended consumption refers to activities that consist in re-experiencing a life experience, for instance sharing stories/photographs or blogging.\\ud \\ud Methodology\\ud \\ud Using a directed qualitative content analysis, Hubbs and Brand's (2010) framework is applied to analyze the content of 19 travel blogs and develop ...

  2. Life Extending Minimum-Time Path Planning for Hexapod Robot

    Directory of Open Access Journals (Sweden)

    Xin Wu

    2011-06-01

    Full Text Available This paper presents a minimum‐time path planning scheme for life‐extending operation of legged robots, illustrated with a six‐legged walking robot (hexapod. The focus of this study is on extending the bearing fatigue life for leg joints. As a typical treatment, the minimum‐time path planning is performed through a bisecting‐plane (BP algorithm with the constraints of maximum joint angular velocity and acceleration. Based on bearing fatigue life theory, its fatigue life increases while the dynamic radial force on the bearing decreases. By imposing more rigorous constraint on the dynamic radial force, the minimum‐time path planning algorithm is thus revised by reinforcing the constraint of maximum radial force based on the expectation of life extension. A symmetric hexapod with 18 degree‐of‐freedom (DOF is adopted as the illustrative example for simulation study. The simulation results validate the effectiveness of possible life extending with moderate compromise in transient performance.

  3. PLEX '91 - extending the life of nuclear plant

    International Nuclear Information System (INIS)

    Rippon, S.

    1992-01-01

    Operating nuclear plants beyond their designed life offers utilities substantial financial rewards - providing that the licensing authority agrees. In some cases this may provide the cheapest form of additional generating capacity, in others it might be the only alternative if the constraints on new plant construction are very harsh. A report is presented from the PLEX '91 conference in Berlin on the technical, regulatory and economic considerations taken into account in extending the life of reactors. (author)

  4. Extending Wireless Rechargeable Sensor Network Life without Full Knowledge.

    Science.gov (United States)

    Najeeb, Najeeb W; Detweiler, Carrick

    2017-07-17

    When extending the life of Wireless Rechargeable Sensor Networks (WRSN), one challenge is charging networks as they grow larger. Overcoming this limitation will render a WRSN more practical and highly adaptable to growth in the real world. Most charging algorithms require a priori full knowledge of sensor nodes' power levels in order to determine the nodes that require charging. In this work, we present a probabilistic algorithm that extends the life of scalable WRSN without a priori power knowledge and without full network exploration. We develop a probability bound on the power level of the sensor nodes and utilize this bound to make decisions while exploring a WRSN. We verify the algorithm by simulating a wireless power transfer unmanned aerial vehicle, and charging a WRSN to extend its life. Our results show that, without knowledge, our proposed algorithm extends the life of a WRSN on average 90% of what an optimal full knowledge algorithm can achieve. This means that the charging robot does not need to explore the whole network, which enables the scaling of WRSN. We analyze the impact of network parameters on our algorithm and show that it is insensitive to a large range of parameter values.

  5. Extending Wireless Rechargeable Sensor Network Life without Full Knowledge

    Directory of Open Access Journals (Sweden)

    Najeeb W. Najeeb

    2017-07-01

    Full Text Available When extending the life of Wireless Rechargeable Sensor Networks (WRSN, one challenge is charging networks as they grow larger. Overcoming this limitation will render a WRSN more practical and highly adaptable to growth in the real world. Most charging algorithms require a priori full knowledge of sensor nodes’ power levels in order to determine the nodes that require charging. In this work, we present a probabilistic algorithm that extends the life of scalable WRSN without a priori power knowledge and without full network exploration. We develop a probability bound on the power level of the sensor nodes and utilize this bound to make decisions while exploring a WRSN. We verify the algorithm by simulating a wireless power transfer unmanned aerial vehicle, and charging a WRSN to extend its life. Our results show that, without knowledge, our proposed algorithm extends the life of a WRSN on average 90% of what an optimal full knowledge algorithm can achieve. This means that the charging robot does not need to explore the whole network, which enables the scaling of WRSN. We analyze the impact of network parameters on our algorithm and show that it is insensitive to a large range of parameter values.

  6. Extended Music Education Enhances the Quality of School Life

    Science.gov (United States)

    Eerola, Päivi-Sisko; Eerola, Tuomas

    2014-01-01

    The claim of whether music education can create social benefits in the school environment was tested in 10 Finnish schools with an extended music curricular class and control classes. The quality of school life (QSL) was assessed by a representative sample ("N" = 735) of pupils at years 3 and 6 (9- and 12-years-olds). The results showed…

  7. 49 CFR 393.45 - Brake tubing and hoses; hose assemblies and end fittings.

    Science.gov (United States)

    2010-10-01

    ... fittings. 393.45 Section 393.45 Transportation Other Regulations Relating to Transportation (Continued... assemblies and end fittings. (a) General construction requirements for tubing and hoses, assemblies, and end fittings. All brake tubing and hoses, brake hose assemblies, and brake hose end fittings must meet the...

  8. Reliability and extended-life potential of EBR-II

    International Nuclear Information System (INIS)

    King, R.W.

    1985-01-01

    Although the longlife potential of liquid-metal-cooled reactors (LMRs) has been only partially demonstrated, many factors point to the potential for exceptionally long life. EBR-II has the opportunity to become the first LMR to achieve an operational lifetime of 30 years or more. In 1984 a study of the extended-life potential of EBR-II identified the factors that contribute to the continued successful operation of EBR-II as a power reactor and experimental facility. Also identified were factors that could cause disruptions in the useful life of the facility. Although no factors were found that would inherently limit the life of EBR-II, measures were identified that could help ensure continued plant availability. These measures include the implementation of more effective surveillance, diagnostic, and control systems to complement the inherent safety and reliability features of EBR-II. An operating lifetime of well beyond 30 years is certainly feasible

  9. Accumulation of anthocyanins in tomato skin extends shelf life.

    Science.gov (United States)

    Bassolino, Laura; Zhang, Yang; Schoonbeek, Henk-Jan; Kiferle, Claudia; Perata, Pierdomenico; Martin, Cathie

    2013-11-01

    Shelf life is one of the most important traits for the tomato (Solanum lycopersicum) industry. Two key factors, post-harvest over-ripening and susceptibility to post-harvest pathogen infection, determine tomato shelf life. Anthocyanins accumulate in the skin of Aft/Aft atv/atv tomatoes, the result of introgressing alleles affecting anthocyanin biosynthesis in fruit from two wild relatives of tomato, which results in extended fruit shelf life. Compared with ordinary, anthocyanin-less tomatoes, the fruits of Aft/Aft atv/atv keep longer during storage and are less susceptible to Botrytis cinerea, a major tomato pathogen, post-harvest. Using genetically modified tomatoes over-producing anthocyanins, we confirmed that skin-specific accumulation of anthocyanins in tomato is sufficient to reduce the susceptibility of fruit to Botrytis cinerea. Our data indicate that accumulation of anthocyanins in tomato fruit, achieved either by traditional breeding or genetic engineering can be an effective way to extend tomato shelf life. © 2013 The Authors. New Phytologist © 2013 New Phytologist Trust.

  10. Extending The Useful Life Of Older Mass Spectrometers

    International Nuclear Information System (INIS)

    Johnson, S.; Cordaro, J.; Holland, M.; Jones, V.

    2010-01-01

    Thermal ionization and gas mass spectrometers are widely used across the Department of Energy (DOE) Complex and contractor laboratories. These instruments support critical missions, where high reliability and low measurement uncertainty are essential. A growing number of these mass spectrometers are significantly older than their original design life. The reality is that manufacturers have declared many of the instrument models obsolete, with direct replacement parts and service no longer available. Some of these obsolete models do not have a next generation, commercially available replacement. Today's budget conscious economy demands for the use of creative funds management. Therefore, the ability to refurbish (or upgrade) these valuable analytical tools and extending their useful life is a cost effective option. The Savannah River Site (SRS) has the proven expertise to breathe new life into older mass spectrometers, at a significant cost savings compared to the purchase and installation of new instruments. A twenty-seven year old Finnigan MAT-261(trademark) Thermal Ionization Mass Spectrometer (TIMS), located at the SRS F/H Area Production Support Laboratory, has been successfully refurbished. Engineers from the Savannah River National Laboratory (SRNL) fabricated and installed the new electronics. These engineers also provide continued instrument maintenance services. With electronic component drawings being DOE Property, other DOE Complex laboratories have the option to extend the life of their aged Mass Spectrometers.

  11. Design of automotive engine coolant hoses

    Directory of Open Access Journals (Sweden)

    Hrishikesh D BACHCHHAV

    2018-03-01

    Full Text Available In this paper, we are present the performance of engine coolant hoses (radiator hoses used in passenger cars by checking various physical behaviours such as hose leakage, hose burst, hose collapse or any mechanical damage as studied-thru design guidelines, CFD analysis and product validation testing and also check pressure drop of the hoses when engine will be running. The design term is more likely used for technical part modelling using CAD tool. Later on, we will focus on the transformation of the part design to process design. The process design term is more likely used for "tooling design" for manufacturing of the product using CAD Tool. Then inlet hose carries coolant from engine to radiator inlet tank, then coolant circulated in radiator and passed through radiator outlet tank to water pump of engine with the help of outlet hose. After that …nding any leakage, Burst, damage or collapse of hose and pressure drop of the hose with the help of design checklist, CFD Analysis and product validation testing.

  12. Model to Design Drip Hose Lateral Line

    Science.gov (United States)

    Ludwig, Rafael; Cury Saad, João Carlos

    2014-05-01

    Introduction The design criterion for non-pressure compensating drip hose is normally to have 10% of flow variation (Δq) in the lateral line, corresponding to 20% of head pressure variation (ΔH). Longer lateral lines in drip irrigation systems using conventional drippers provide cost reduction, but it is necessary to obtain to the uniformity of irrigation [1]. The use of Δq higher levels can provide longer lateral lines. [4] proposes the use of a 30% Δq and he found that this value resulted in distribution uniformity over 80%. [1] considered it is possible to extend the lateral line length using two emitters spacing in different section. He assumed that the spacing changing point would be at 40% of the total length, because this is approximately the location of the average flow according with [2]. [3] found that, for practical purposes, the average pressure is located at 40% of the length of the lateral line and that until this point it has already consumed 75% of total pressure head loss (hf ). In this case, the challenge for designers is getting longer lateral lines with high values of uniformity. Objective The objective of this study was to develop a model to design longer lateral lines using non-pressure compensating drip hose. Using the developed model, the hypotheses to be evaluated were: a) the use of two different spacing between emitters in the same lateral line allows longer length; b) it is possible to get longer lateral lines using high values of pressure variation in the lateral lines since the distribution uniformity stays below allowable limits. Methodology A computer program was developed in Delphi® based on the model developed and it is able to design lateral lines in level using non-pressure compensating drip hose. The input data are: desired distribution uniformity (DU); initial and final pressure in the lateral line; coefficients of relationship between emitter discharge and pressure head; hose internal diameter; pipe cross-sectional area

  13. Design of a Fast Measuring System for the Section Size of Automobile Rubber Hose Withhold Parts

    Science.gov (United States)

    Meng, Fanwu; Zhang, Teng; Ren, Jingrui

    2017-12-01

    The quality of withhold parts determines the service life of high-pressure rubber hose to a great extent. Leakage at withholding is the main form of high pressure hose failure in the several forms. The quickest and most effective method to detect the withholding quality is measuring the section size of the withhold parts. As long as the section size is in line with the provisions, that is, the quality of hose withholding is qualified. In this paper, the mesurement system which is designed improves low efficiency of manual mesurement.

  14. Optimum Thermal Processing for Extended Shelf-Life (ESL) Milk.

    Science.gov (United States)

    Deeth, Hilton

    2017-11-20

    Extended shelf-life (ESL) or ultra-pasteurized milk is produced by thermal processing using conditions between those used for traditional high-temperature, short-time (HTST) pasteurization and those used for ultra-high-temperature (UHT) sterilization. It should have a refrigerated shelf-life of more than 30 days. To achieve this, the thermal processing has to be quite intense. The challenge is to produce a product that has high bacteriological quality and safety but also very good organoleptic characteristics. Hence the two major aims in producing ESL milk are to inactivate all vegetative bacteria and spores of psychrotrophic bacteria, and to cause minimal chemical change that can result in cooked flavor development. The first aim is focused on inactivation of spores of psychrotrophic bacteria, especially Bacillus cereus because some strains of this organism are pathogenic, some can grow at ≤7 °C and cause spoilage of milk, and the spores of some strains are very heat-resistant. The second aim is minimizing denaturation of β-lactoglobulin (β-Lg) as the extent of denaturation is strongly correlated with the production of volatile sulfur compounds that cause cooked flavor. It is proposed that the heating should have a bactericidal effect, B * (inactivation of thermophilic spores), of >0.3 and cause ≤50% denaturation of β-Lg. This can be best achieved by heating at high temperature for a short holding time using direct heating, and aseptically packaging the product.

  15. Active packaging using ethylene absorber to extend shelf-life

    International Nuclear Information System (INIS)

    Ponce, Patricia; Carbonari, Guilherme L.R.; Lugao, Ademar B.

    2009-01-01

    Ethylene gas is a plant hormone which is produced by fruits and vegetables during ripening and it is also found in the environment. It plays an essential role in normal ripening, but excessive exposure can radically reduce the shelf-life of the product, in some cases inducing undesirable reactions such as development of bitter flavors and loss of chlorophyll (yellowing of greens). The objectives of our work were: to test an active packaging of polyvinyl alcohol (PVA) for apple stored; to test the effect of ethylene absorber agent, impregnated in plastic film, to reduce decay of fresh apple; to study the influence of radiation on the barrier properties, mechanical properties and biodegradability of PVA films. This study evaluated the effect of coating produced from PVA and polyol (glycerol and sorbitol) as plasticizer on apple conservation (75 deg F (24 deg C); 70%RH). The coated product was analyzed for mass loss, color alterations and fungi. The PVA films were produced by casting process (dehydration of a filmogenic solution on Petriplastic dishes) and were irradiated at low doses of 2, 5 and 10 kGy, commonly used in food irradiation. The resulting films were transparent and homogeneous. The active packaged fruits presented higher acceptance, lower microbiological growth, less alterations in acidity, lower weight loss rate during the storage time and an extended shelf-life as compared to the control fruits (without plastic films). (author)

  16. SNEV overexpression extends the life span of human endothelial cells

    International Nuclear Information System (INIS)

    Voglauer, Regina; Chang, Martina Wei-Fen; Dampier, Brigitta; Wieser, Matthias; Baumann, Kristin; Sterovsky, Thomas; Schreiber, Martin; Katinger, Hermann; Grillari, Johannes

    2006-01-01

    In a recent screening for genes downregulated in replicatively senescent human umbilical vein endothelial cells (HUVECs), we have isolated the novel protein SNEV. Since then SNEV has proven as a multifaceted protein playing a role in pre-mRNA splicing, DNA repair, and the ubiquitin/proteosome system. Here, we report that SNEV mRNA decreases in various cell types during replicative senescence, and that it is increased in various immortalized cell lines, as well as in breast tumors, where SNEV transcript levels also correlate with the survival of breast cancer patients. Since these mRNA profiles suggested a role of SNEV in the regulation of cell proliferation, the effect of its overexpression was tested. Thereby, a significant extension of the cellular life span was observed, which was not caused by altered telomerase activity or telomere dynamics but rather by enhanced stress resistance. When SNEV overexpressing cells were treated with bleomycin or bleomycin combined with BSO, inducing DNA damage as well as reactive oxygen species, a significantly lower fraction of apoptotic cells was found in comparison to vector control cells. These data suggest that high levels of SNEV might extend the cellular life span by increasing the resistance to stress or by improving the DNA repair capacity of the cells

  17. Optimum Thermal Processing for Extended Shelf-Life (ESL) Milk

    Science.gov (United States)

    Deeth, Hilton

    2017-01-01

    Extended shelf-life (ESL) or ultra-pasteurized milk is produced by thermal processing using conditions between those used for traditional high-temperature, short-time (HTST) pasteurization and those used for ultra-high-temperature (UHT) sterilization. It should have a refrigerated shelf-life of more than 30 days. To achieve this, the thermal processing has to be quite intense. The challenge is to produce a product that has high bacteriological quality and safety but also very good organoleptic characteristics. Hence the two major aims in producing ESL milk are to inactivate all vegetative bacteria and spores of psychrotrophic bacteria, and to cause minimal chemical change that can result in cooked flavor development. The first aim is focused on inactivation of spores of psychrotrophic bacteria, especially Bacillus cereus because some strains of this organism are pathogenic, some can grow at ≤7 °C and cause spoilage of milk, and the spores of some strains are very heat-resistant. The second aim is minimizing denaturation of β-lactoglobulin (β-Lg) as the extent of denaturation is strongly correlated with the production of volatile sulfur compounds that cause cooked flavor. It is proposed that the heating should have a bactericidal effect, B* (inactivation of thermophilic spores), of >0.3 and cause ≤50% denaturation of β-Lg. This can be best achieved by heating at high temperature for a short holding time using direct heating, and aseptically packaging the product. PMID:29156617

  18. Optimum Thermal Processing for Extended Shelf-Life (ESL Milk

    Directory of Open Access Journals (Sweden)

    Hilton Deeth

    2017-11-01

    Full Text Available Extended shelf-life (ESL or ultra-pasteurized milk is produced by thermal processing using conditions between those used for traditional high-temperature, short-time (HTST pasteurization and those used for ultra-high-temperature (UHT sterilization. It should have a refrigerated shelf-life of more than 30 days. To achieve this, the thermal processing has to be quite intense. The challenge is to produce a product that has high bacteriological quality and safety but also very good organoleptic characteristics. Hence the two major aims in producing ESL milk are to inactivate all vegetative bacteria and spores of psychrotrophic bacteria, and to cause minimal chemical change that can result in cooked flavor development. The first aim is focused on inactivation of spores of psychrotrophic bacteria, especially Bacillus cereus because some strains of this organism are pathogenic, some can grow at ≤7 °C and cause spoilage of milk, and the spores of some strains are very heat-resistant. The second aim is minimizing denaturation of β-lactoglobulin (β-Lg as the extent of denaturation is strongly correlated with the production of volatile sulfur compounds that cause cooked flavor. It is proposed that the heating should have a bactericidal effect, B* (inactivation of thermophilic spores, of >0.3 and cause ≤50% denaturation of β-Lg. This can be best achieved by heating at high temperature for a short holding time using direct heating, and aseptically packaging the product.

  19. 41 CFR 101-27.207-3 - Marking material to show extended shelf life.

    Science.gov (United States)

    2010-07-01

    ... extended shelf life. 101-27.207-3 Section 101-27.207-3 Public Contracts and Property Management Federal...-INVENTORY MANAGEMENT 27.2-Management of Shelf-Life Materials § 101-27.207-3 Marking material to show extended shelf life. When the shelf-life period of Type II material (except for critical end-use items as...

  20. Solid-state lighting life prediction using extended Kalman filter

    Energy Technology Data Exchange (ETDEWEB)

    Lall, Pradeep [Auburn Univ., AL (United States); Wei, Junchao [Auburn Univ., AL (United States); Davis, Lynn [RTI International, Durham, NC (United States)

    2013-07-16

    Solid-state lighting (SSL) luminaires containing light emitting diodes (LEDs) have the potential of seeing excessive temperatures when being transported across country or being stored in non-climate controlled warehouses. They are also being used in outdoor applications in desert environments that see little or no humidity but will experience extremely high temperatures during the day. This makes it important to increase our understanding of what effects high temperature exposure for a prolonged period of time will have on the usability and survivability of these devices. The U.S. Department of Energy has made a long term commitment to advance the efficiency, understanding and development of solid-state lighting (SSL) and is making a strong push for the acceptance and use of SSL products to reduce overall energy consumption attributable to lighting. Traditional light sources “burn out” at end-of-life. For an incandescent bulb, the lamp life is defined by B50 life. However, the LEDs have no filament to “burn”. The LEDs continually degrade and the light output decreases eventually below useful levels causing failure. Presently, the TM-21 test standard is used to predict the L70 life of SSL Luminaires from LM-80 test data. The TM-21 model uses an Arrhenius Equation with an Activation Energy, Pre-decay factor and Decay Rates. Several failure mechanisms may be active in a luminaire at a single time causing lumen depreciation. The underlying TM-21 Arrhenius Model may not capture the failure physics in presence of multiple failure mechanisms. Correlation of lumen maintenance with underlying physics of degradation at system-level is needed. In this paper, a Kalman Filter and Extended Kalman Filters have been used to develop a 70% Lumen Maintenance Life Prediction Model for a LEDs used in SSL luminaires. This model can be used to calculate acceleration factors, evaluate failure-probability and identify ALT methodologies for reducing test time. Ten-thousand hour LM

  1. 46 CFR 154.554 - Cargo hose: Bursting pressure.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo hose: Bursting pressure. 154.554 Section 154.554... Hose § 154.554 Cargo hose: Bursting pressure. Cargo hose that may be exposed to the pressure in the cargo tank, the cargo pump discharge, or the vapor compressor discharge must have a bursting pressure of...

  2. 46 CFR 154.560 - Cargo hose: Prototype test.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo hose: Prototype test. 154.560 Section 154.560... Hose § 154.560 Cargo hose: Prototype test. (a) Each cargo hose must be of a type that passes a prototype test at a pressure of at least five times its maximum working pressure at or below the minimum...

  3. 46 CFR 105.35-15 - Fire hose.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Fire hose. 105.35-15 Section 105.35-15 Shipping COAST... VESSELS DISPENSING PETROLEUM PRODUCTS Fire Extinguishing Equipment § 105.35-15 Fire hose. (a) One length of fire hose shall be provided for each fire hydrant required. (b) Fire hose may be commercial fire...

  4. 30 CFR 57.13021 - High-pressure hose connections.

    Science.gov (United States)

    2010-07-01

    ... Air and Boilers § 57.13021 High-pressure hose connections. Except where automatic shutoff valves are... 30 Mineral Resources 1 2010-07-01 2010-07-01 false High-pressure hose connections. 57.13021...-pressure hose lines of 3/4-inch inside diameter or larger, and between high-pressure hose lines of 3/4-inch...

  5. Fluid Flow through Pipes--Another Look at Fire Hoses and Garden Hoses.

    Science.gov (United States)

    Brouwer, W.; Paranjape, B. V.

    1991-01-01

    The forward force of water on a hose is calculated using only the pressure gradient, the radius and length of the hose. The misconception about recoil on the nozzle is discussed. Dissipation energy and the consequent heat generation in a fluid flow are also described. (KR)

  6. Determining the inventory impact of extended-shelf-life platelets with a network simulation model.

    Science.gov (United States)

    Blake, John T

    2017-12-01

    The regulatory shelf life for platelets (PLTs) in many jurisdictions is 5 days. PLT shelf life can be extended to 7 days with an enhanced bacterial detection algorithm. Enhanced testing, however, comes at a cost, which may be offset by reductions in wastage due to longer shelf life. This article describes a method for estimating systemwide reductions in PLT outdates after PLT shelf life is extended. A simulation was used to evaluate the impact of an extended PLT shelf life within a national blood network. A network model of the Canadian Blood Services PLT supply chain was built and validated. PLT shelf life was extended from 5 days to 6, 7, and 8 days and runs were completed to determine the impact on outdates. Results suggest that, in general, a 16.3% reduction in PLT wastage can be expected with each additional day that PLT shelf life is extended. Both suppliers and hospitals will experience fewer outdating units, but wastage will decrease at a faster rate at hospitals. No effect was seen by blood group, but there was some evidence that supplier site characteristics influences both the number of units wasted and the site's ability to benefit from extended-shelf-life PLTs. Extended-shelf-life PLTs will reduce wastage within a blood supply chain. At 7 days, an improvement of 38% reduction in wastage can be expected with outdates being equally distributed between suppliers and hospital customers. © 2017 AABB.

  7. Basic and applied life science extended by neutron

    International Nuclear Information System (INIS)

    Nakagawa, Hiroshi; Kataoka, Mikio

    2017-01-01

    Life science is expected to be one of the major subjects of neutron research. The quantum beam properties of neutron, isotope effect and inelastic/quasi-elastic scattering are useful for studying crystal structures, solution structures and dynamic structures of biomolecules. Research on physical properties of biological materials by inelastic scattering is promising as applied research such as food science. The high-intensity pulse neutrons realized by the accelerator not only has developed the life science research so far, but also is opening a gate to the academic field which has never been used before. (author)

  8. Extending Vulnerability Assessment to Include Life Stages Considerations.

    Science.gov (United States)

    Hodgson, Emma E; Essington, Timothy E; Kaplan, Isaac C

    2016-01-01

    Species are experiencing a suite of novel stressors from anthropogenic activities that have impacts at multiple scales. Vulnerability assessment is one tool to evaluate the likely impacts that these stressors pose to species so that high-vulnerability cases can be identified and prioritized for monitoring, protection, or mitigation. Commonly used semi-quantitative methods lack a framework to explicitly account for differences in exposure to stressors and organism responses across life stages. Here we propose a modification to commonly used spatial vulnerability assessment methods that includes such an approach, using ocean acidification in the California Current as an illustrative case study. Life stage considerations were included by assessing vulnerability of each life stage to ocean acidification and were used to estimate population vulnerability in two ways. We set population vulnerability equal to: (1) the maximum stage vulnerability and (2) a weighted mean across all stages, with weights calculated using Lefkovitch matrix models. Vulnerability was found to vary across life stages for the six species explored in this case study: two krill-Euphausia pacifica and Thysanoessa spinifera, pteropod-Limacina helicina, pink shrimp-Pandalus jordani, Dungeness crab-Metacarcinus magister and Pacific hake-Merluccius productus. The maximum vulnerability estimates ranged from larval to subadult and adult stages with no consistent stage having maximum vulnerability across species. Similarly, integrated vulnerability metrics varied greatly across species. A comparison showed that some species had vulnerabilities that were similar between the two metrics, while other species' vulnerabilities varied substantially between the two metrics. These differences primarily resulted from cases where the most vulnerable stage had a low relative weight. We compare these methods and explore circumstances where each method may be appropriate.

  9. Extending Pickering Fuel Channel Life to 247,000 EFPH (2020)

    International Nuclear Information System (INIS)

    Malek, I.

    2013-01-01

    This presentation is about extending the life of PNGS Pressure tubes from 210,000 EFPH (Effective Full Power Hours) to 247,000 EFPH. The l license renewal is in 2013 (R & D defined in 2009). The unknowns are the extent of degradation in some key areas. There are regulatory requirements for fuel channel extended life. It is necessary to integrate inspection capability and do-ability in outages. This would result in safe operation and demonstrated margin to extend life with operation to 2020.

  10. Extended life for the Borssele reactor. Risks and cost

    International Nuclear Information System (INIS)

    Van Gelder, J.W.; De Rijk, P.

    2005-01-01

    In the last few years several decisions were taken by the Dutch government with respect to the service life of the nuclear power reactor Borssele. The last decision was taken in 2003 to close the reactor in the year 2013. However, the discussion started again while it appears, according to the Dutch Minister of State for the Environment, there is not enough political and legal basis to enforce closure of the reactor in 2013. In this report insight is given into the risks and societal cost to continue the operation of the Borssele reactor after 2013 [nl

  11. 46 CFR 193.10-10 - Fire hydrants and hose.

    Science.gov (United States)

    2010-10-01

    ... the vessel, other than main machinery spaces, may be reached with at least 2 streams of water from separate outlets, at least one of which must be from a single length of hose. In main machinery spaces, all... decks where no protection is afforded to the hose in heavy weather, the hose may be temporarily removed...

  12. 'He has a life, a soul, a meaning that extends far deeper than his ...

    African Journals Online (AJOL)

    'He has a life, a soul, a meaning that extends far deeper than his medical assessment … .': The role of reflective diaries in enhancing reflective practice during a rural community physiotherapy placement.

  13. Shelf Life of PMR Polyimide Monomer Solutions and Prepregs Extended

    Science.gov (United States)

    Alston, William B.; Scheiman, Daniel A.

    2000-01-01

    PMR (Polymerization of Monomeric Reactants) technology was developed in the mid-1970's at the NASA Glenn Research Center at Lewis Field for fabricating high-temperature stable polyimide composites. This technology allowed a solution of polyimide monomers or prepreg (a fiber, such as glass or graphite, impregnated with PMR polyimide monomers) to be thermally cured without the release of volatiles that cause the formation of voids unlike the non-PMR technology used for polyimide condensation type resins. The initial PMR resin introduced as PMR 15 is still commercially available and is used worldwide by aerospace industries as the state-of-the-art resin for high-temperature polyimide composite applications. PMR 15 offers easy composite processing, excellent composite mechanical property retention, a long lifetime at use temperatures of 500 to 550 F, and relatively low cost. Later, second-generation PMR resin versions, such as PMR II 50 and VCAP 75, offer improvements in the upper-use temperature (to 700 F) and in the useful life at temperature without major compromises in processing and property retention but with significant increases in resin cost. Newer versions of nontoxic (non-methylene dianiline) PMR resins, such as BAX PMR 15, offer similar advantages as originally found for PMR 15 but also with significant increases in resin cost. Thus, the current scope of the entire PMR technology available meets a wide range of aeronautical requirements for polymer composite applications.

  14. The aging process and potential interventions to extend life expectancy

    Directory of Open Access Journals (Sweden)

    Matteo Tosato

    2007-10-01

    Full Text Available Matteo Tosato1, Valentina Zamboni1, Alessandro Ferrini1, Matteo Cesari1,21Department of Gerontology, Geriatrics and Physiatry; Catholic University of Sacred Heart, Rome, Italy; 2Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL, USAAbstract: Aging is commonly defined as the accumulation of diverse deleterious changes occurring in cells and tissues with advancing age that are responsible for the increased risk of disease and death. The major theories of aging are all specific of a particular cause of aging, providing useful and important insights for the understanding of age-related physiological changes. However, a global view of them is needed when debating of a process which is still obscure in some of its aspects. In this context, the search for a single cause of aging has recently been replaced by the view of aging as an extremely complex, multifactorial process. Therefore, the different theories of aging should not be considered as mutually exclusive, but complementary of others in the explanation of some or all the features of the normal aging process. To date, no convincing evidence showing the administration of existing “anti-aging” remedies can slow aging or increase longevity in humans is available. Nevertheless, several studies on animal models have shown that aging rates and life expectancy can be modified. The present review provides an overlook of the most commonly accepted theories of aging, providing current evidence of those interventions aimed at modifying the aging process.Keywords: Aging, anti-aging medicine, caloric restriction, oxidative damage, inflammation, physical exercise

  15. System to Repair Deformations in Elastomeric Hoses

    Science.gov (United States)

    2017-01-05

    February 2017 The below identified patent application is available for licensing . Requests for information should be addressed to...point. The primary disadvantage with these methods is the labor associated with wrapping and unwrapping thousands of feet of hose. [0006] Another

  16. Prerequisites and driving forces behind an extended working life among older workers.

    Science.gov (United States)

    Hovbrandt, Pia; Håkansson, Carita; Albin, Maria; Carlsson, Gunilla; Nilsson, Kerstin

    2017-11-28

    Reforms are changing pension systems in many European countries, in order to both restrict early retirement and force people to extend their working life. From occupational therapy and occupational science perspectives, studies focusing on aspects of working life that motivate the older worker is urgent. The aim was to describe incentives behind an extended working life among people over age 65. Focus group methodology was used, with participants ages 66-71, from varying work fields: construction and technical companies and the municipal elderly care sector. Work was considered important and valuable to the degree of how challenging work was, the possibilities for inclusion in a team of colleagues and the chances for better personal finances. Amongst all, the participants expressed a feeling of a strengthened identity by being challenged and having the opportunity to manage working tasks. The finding showed the actual reasons behind an extended working life among older workers. However, a risk of rising social inequity may appear with increased working life if older people are forced to extend their working life due to a difficult financial situation as a pensioner. A variety of retirement options and initiatives in order to support older workers are justified.

  17. Extending Working Life: Which Competencies are Crucial in Near-Retirement Age?

    Science.gov (United States)

    Wiktorowicz, Justyna

    2018-01-01

    Nowadays, one of the most important economic and social phenomena is population ageing. Due to the low activity rate of older people, one of the most important challenges is to take various actions involving active ageing, which is supposed to extending working life, and along with it-improve the competencies of older people. The aim of this paper is to evaluate the relevance of different competencies for extending working life, with limiting the analysis for Poland. The paper also assesses the competencies of mature Polish people (aged 50+, but still in working age). In the statistical analysis, I used logistic regression, as well as descriptive statistics and appropriate statistical tests. The results show that among the actions aimed at extending working life, the most important are those related to lifelong learning, targeted at improving the competencies of the older generation. The competencies (both soft and hard) of people aged 50+ are more important than their formal education.

  18. How a mutation that slows aging can also disproportionately extend end-of-life decrepitude

    Science.gov (United States)

    Podshivalova, Katie; Kerr, Rex A.; Kenyon, Cynthia

    2017-01-01

    Summary The goal of aging research is to extend healthy, active life. For decades, C. elegans daf-2 insulin/IGF-1 receptor mutants have served as a model for extended lifespan and youthfulness. However, a recent report suggested that their longevity is associated with an undesirable phenotype: a disproportionately long period of decrepitude at the end of life. In a human population, such an outcome would be a burden to society, bringing into question the relevance of daf-2 mutants as a model for life extension. However, here we report that, following an extended period of movement, daf-2 mutants survive longer in a decrepit state because of a beneficial trait: they are resistant to colonization of the digestive tract by dietary bacteria, a condition that leads to premature death in wild type and prevents their manifestation of decrepitude. If bacterial colonization is prevented, daf-2 mutants lead chronologically and proportionately healthier lives relative to wild type. PMID:28423308

  19. IMPROVING PRODUCTION OF LOW PRESSURE HOSES

    OpenAIRE

    Piotr Sygut; Marek Krynke

    2018-01-01

    The paper presents the results of research carried out in one of the domestic companies producing rubber and plastics products for the automotive industry. The results of the evaluation of the quality control function during production of the low pressure hoses and the characteristics of the main ma-chine taking part in this production process are presented. An analysis of the results of the evaluation of factors influencing the quality of production is presented and guidelines for improving ...

  20. Extending shelf life of poultry and red meat by irradiation processing

    International Nuclear Information System (INIS)

    Thayer, D.W.

    1993-01-01

    Research has demonstrated that ionizing radiation can inactivate parasites, eliminate or greatly reduce the populations of microbial pathogens, and extend the shelf life while preserving the desired nutritional and sensory properties of refrigerated poultry and red meats. Foodborne pathogens can be greatly reduced in population and sometimes completely eliminated from foods by low doses of ionizing radiation. The shelf life of poultry, pork, and beef can be significantly extended by treatment with ionizing radiation. Combination treatments with vacuum packaging or modified atmosphere packaging and ionizing radiation have produced better than predicted results. Additional research is needed on the combined processes

  1. The impact of extended half-life versus conventional factor product on hemophilia caregiver burden.

    Science.gov (United States)

    Schwartz, Carolyn E; Powell, Victoria E; Su, Jun; Zhang, Jie; Eldar-Lissai, Adi

    2018-02-01

    Extended half-life factor products have reduced annualized bleeding rates in hemophilia patients. The impact of extended half-life versus conventional factor products on hemophilia caregiver burden has not been investigated. This study aimed to evaluate caregiver burden in extended half-life versus conventional factor products for hemophilia A and B. This cross-sectional web-based study of caregivers of people with hemophilia A or B was recruited from a panel research company and by word of mouth. Participants completed the Hemophilia Caregiver Impact measure, the PedsQL Family Impact Module (PedsQL), and the Work Productivity and Activity Impairment Questionnaire (WPAI). We also collected demographic, insurance coverage, and medical information related to the hemophilia patient(s). Burden differences were assessed using linear regression and matched cohort analyses. The sample (n = 448) included 49 people who were caring for people on extended half-life factor products. Worse caregiver burden was associated with more infusions per week and more bleeds in the past 6 months. Regression analyses suggested that caring for someone who is on a extended half-life factor product is associated with lower emotional impact (β = - 0.11, p life factor product had lower Emotional Impact and Practical Impact scores (t = - 2.95 and - 2.94, respectively, p life factor products appears to reduce the emotional distress and practical burden of caregiving. Future work should evaluate the longitudinal impact.

  2. How a Mutation that Slows Aging Can Also Disproportionately Extend End-of-Life Decrepitude

    Directory of Open Access Journals (Sweden)

    Katie Podshivalova

    2017-04-01

    Full Text Available Summary: The goal of aging research is to extend healthy, active life. For decades, C. elegans daf-2 insulin/insulin-like growth factor 1 (IGF-1 receptor mutants have served as a model for extended lifespan and youthfulness. However, a recent report suggested that their longevity is associated with an undesirable phenotype: a disproportionately long period of decrepitude at the end of life. In the human population, such an outcome would be a burden to society, bringing into question the relevance of daf-2 mutants as a model for life extension. However, here we report that, following an extended period of movement, daf-2 mutants survive longer in a decrepit state because of a beneficial trait: they are resistant to colonization of the digestive tract by dietary bacteria, a condition that leads to premature death in the wild-type and prevents their manifestation of decrepitude. If bacterial colonization is prevented, then daf-2 mutants lead both chronologically and proportionately healthier lives relative to the wild-type. : Podshivalova et al. show that long-lived C. elegans insulin/IGF-1 receptor mutants remain active longer but then resist bacterially induced mortality, allowing them to survive into a state of end-of-life decrepitude. Thus, changes that slow aging and also prevent an age-associated catastrophe can extend both the youthful and infirm periods of life. Keywords: aging, lifespan, healthspan, daf-2, mortality, IGF-1, pathogenesis

  3. An extended family suddenly confronted with a life-threatening hereditary arrhythmia

    NARCIS (Netherlands)

    Hendriks, K. S. W. H.; van Langen, I. M.; van Tintelen, J. P.; Grosfeld, F. J. M.; Wilde, A. A. M.; ten Kroode, H. F. J.

    2005-01-01

    This exploratory study serves to illustrate the psychological impact on an extended family in the process of genetic counselling and testing for a potentially life-threatening arrhythmia, the long-QT syndrome (LQTS). All members of the third generation and their partners (n=11) were interviewed, the

  4. An extended family suddenly confronted with a life-threatening hereditary arrhythmia

    NARCIS (Netherlands)

    Hendriks, K.S.W.H.; Van Langen, I.M.; Van Tintelen, J.P.; Grosfeld, F.J.M.; Wilde, A.A.M.; Ten Kroode, H.F.J.

    2005-01-01

    Objective. This exploratory study serves to illustrate the psychological impact on an extended family in the process of genetic counselling and testing for a potentially life-threatening arrhythmia, the long-QT syndrome (LQTS). Method. All members of the third generation and their partners (n=11)

  5. Extending the economic life of the Ogallala Aquifer with water conservation policies in the Texas panhandle

    Science.gov (United States)

    The continued decline in the availability of water from the Ogallala Aquifer in the Texas Panhandle has led to an increased interest in conservation policies designed to extend the life of the aquifer and sustain rural economies. Four counties were chosen for evaluation. This study evaluates the eff...

  6. Social security wealth and aggregate consumption : An extended life-cycle model estimated for The Netherlands

    NARCIS (Netherlands)

    Zant, W.

    In this paper a method is developed to calculate a wealth variable accounting for the existence of the basic old-age provisions in The Netherlands (AOW). In line with Feldstein's extended life-cycle model, consumption functions with (gross) social security wealth are estimated for The Netherlands

  7. Industrial waste - destination and valuation techniques of floating hoses: case study in Macaé, RJ

    Directory of Open Access Journals (Sweden)

    Marlon de Almeida Clemente Silva

    2017-10-01

    Full Text Available A large part of the oil extracted in Brazil today, is drained to the coast, or even transported to larger vessels through Floating Hoses. This oil unloading operation is called Offloading, it is of fundamental importance for the performance of offshore operations. These operating units use storage systems and oil relief, which can be FSO (Floating Storage Unit and Transfer or FPSO (Floating Production Unit, Stockpiling and Transfer. In this oil transshipment scenario, floating hoses have primary role therefore they are responsible for this operation. The Floating Hoses after useful life are discarded. How do the environmentally correct disposal of this waste? The destination most used for this waste are the landfills Class 2, for non-hazardous waste. In this study, we attempted to develop appropriate allocation techniques for Floating Hose, in order to obtain a greater appreciation potential of the materials that compose it, as well as presenting the risk of these being put up in a landfill, even if it is a controlled landfill. This technique is based on a so-called Reverse Manufacturing, all components are reused and recovered, with a more environmentally sound and economically viable destination. The research methodology was based on empirical studies of phenomenological framework, involving operational staff of a medium-sized company with a rising share of Treatment and Waste Disposal Market, in the city of Macaé. It was evidenced in the survey that there is a possibility of potential gains from the application of reverse manufacturing techniques of hoses, both in terms of environmental liability reductions and the financial return through the recovery of materials that compose them.

  8. DEVELOPMENT OF RECOMMENDATIONS FOR EXTENDING THE USEFUL LIFE OF PASSENGER CARS

    Directory of Open Access Journals (Sweden)

    S. V. Myamlin

    2015-11-01

    Full Text Available Purpose. The vast majority of passenger car fleet of «Ukrzaliznytsia» have cars with outlasted service life. In this regard there is a need to find methods to justify the extending useful life of passenger cars and to assess the car body frame residual life conformity to the operating load for the next life time. Methodology. The selection of cars enforced technical diagnostics of cars to detect the level of corrosion and mechanical damage. The following steps provided the car body frame strength analysis on the basis of experimental static and impact strength tests, the longitudinal force effect endurance tests as well as assessment and forecasting of conformity of car body operating life for the next period. Findings The car survey before testing showed that the technical condition of sleeper cars (SSC is better than that of open-type cars (SOC. So, in SSC cars the thinning of the main load-bearing elements due to corrosion does not exceed 10%, there are no cracks, deformations, rack breakages, etc. At the same time in SOC cars the thinning due to local corrosion reached 35%. There are deformations and corrosion damage of side sill Zshape of both cars, single corner post breakages, damage to the joints of longitudinal tie rod and span bolsters. The conducted static and impact strength tests with following strength assessment of the car structural members showed that the strength of the latter is provided according to the normative documents, and these cars pose no threat to traffic safety. The impact endurance tests showed that all the cars passed the endurance tests without damage, which would prevent from testing and could not be removed during the next depot repair or overhaul, and had life length that allows them to extend the useful life for the next period. Originality. The results of experimental studies show that passenger cars after 28 … 30 and 33… 35 years of operation meet the requirements of strength and safety in accordance

  9. 30 CFR 56.13021 - High-pressure hose connections.

    Science.gov (United States)

    2010-07-01

    ... and Boilers § 56.13021 High-pressure hose connections. Except where automatic shutoff valves are used, safety chains or other suitable locking devices shall be used at connections to machines of high-pressure... 30 Mineral Resources 1 2010-07-01 2010-07-01 false High-pressure hose connections. 56.13021...

  10. 46 CFR 197.312 - Breathing supply hoses.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Breathing supply hoses. 197.312 Section 197.312 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE OCCUPATIONAL SAFETY AND HEALTH STANDARDS GENERAL PROVISIONS Commercial Diving Operations Equipment § 197.312 Breathing supply hoses. (a) Each...

  11. Fuzzy Life-Extending Control of Anti-Lock Braking System

    Directory of Open Access Journals (Sweden)

    Ahmed M. El-Garhy

    2013-12-01

    Full Text Available The repeated operation of the Anti-Lock Braking System (ABS causes accumulation of structural damages in its different subsystems leading to reduction in their functional life time. This paper proposes a Fuzzy Logic based Life-Extending Control (FLEC system for increasing the service life of the ABS. FLEC achieves significant improvement in service life by the trade-off between satisfactory dynamic performance and safe operation. The proposed FLEC incorporates structural damage model of the ABS. The model utilizes the dynamic behavior of the ABS and predicts the wear rates of the brake pads/disc. Based on the predicted wear rates, the proposed fuzzy logic controller modifies its control strategy on-line to keep safe operation leading to increase in service time of the ABS. FLEC is fine tuned via genetic algorithm and its effectiveness is verified through simulations of emergency stops of a passenger vehicle model.

  12. Effects of Modified Atmosphere Packaging, Food Life Extenders and Temperature on the Shelf Life of Ready-Made Dishes.

    Science.gov (United States)

    Sato, Jun; Maenishi, Takuya; Saito, Yuki; Masuda, Toshiro; Kadotani, Naoki; Kozakai, Hiroshi; Ito, Masanori

    2016-01-01

    The combined effect of several microbial control factors including gas barrier of containers, modified atmosphere packaging, food life extenders and storage temperature was discussed in order to determine the possibility for improving the shelf life for hamburger steak and deepfried chicken, representative ready-made dishes sold at convenience stores in Japan. Multiple measures including cold storage were effective in improving the shelf life of ready-made dishes. It was also suggested that storage tests for ready-made dishes should be conducted at 10℃, a practical temperature, to confirm the storable period, as well as at 15℃, an adequate abuse temperature, to confirm the effects of various microbial control factors. In the present study, the test group 4 (nitrogen + barrier containers + pH modifier) performed most favorably at both temperatures, indicating the efficacy of multiple means including "cold storage" in improving the shelf life (extending the consume-by date) of ready-made dishes. All strains isolated from the tested hamburger steak and deep-fried chicken were common food contaminant bacterial species.

  13. Irradiation of mushrooms (Agaricus campestris L) to extend their shelf-life

    International Nuclear Information System (INIS)

    Lescano, G.

    1990-01-01

    Mushrooms (Agaricus campestris L) were irradiated with 1.0; 2.0 and 3.0 kGy, being then stored either at 10 deg C ± 1 deg C or at room temperature (20 deg C ± 2 deg C), with the purpose of determining the most convenient condition to extend their shelf-life. It is concluded that 3.0 kGy and 10 deg C are the most suitable for that, leading to the inhibition of cap opening and stem elongation, less darkening and no evidence of fungal development until 17th day. Subsequentely almost a duplication of their shelf-life was obtained. (Author) [es

  14. TO THE ISSUE OF EXTENDING THE SERVICE LIFE OF CARS FOR TRANSPORTATION OF PELLETS

    Directory of Open Access Journals (Sweden)

    V. H. Anofriev

    2016-06-01

    Full Text Available Purpose. Freight rolling stock of «Ukrzaliznytsia» primarily has cars that are overaged. The same situation is observed in the park of specialized cars. So the car fleet for the transport of pellets consists of about 50% of cars that served one-and-a-half and more lifetimes. However, the volume of shipments of iron ore is constant for a number of years. In this regard, there is a need to find methods to justify continuing useful life of cars and to assess the conformity of residual life of the car body structure to operating load for an extended period of use. Methodology. When selecting the cars for the test their condition underwent technical diagnosis in order to identify the level of corrosion and mechanical damage. The next stages of the tests included the experimental determination of the loading level and the stress state of car body carcass based on strength and endurance tests and the evaluation of the possible values of the extended period of operation. Findings. Pre-test diagnosing of cars showed that the technical condition of cars for transportation of pellets, as a whole, is in satisfactory condition. Carried out static and impact strength tests with subsequent evaluation of strength of the car structural elements showed that the strength of the latter is provided in accordance with regulations and such cars do not threaten the traffic safety. Shock endurance tests have shown that all the cars have passed endurance tests with no damage that would impede testing and could not be removed during scheduled repairs. The cars had lifelength that allows prolong their useful life after one-and-a-half lifetime. Originality. The work presents the estimate of the residual life of bodies of pellet transportation cars, which spent one-and-a-half of the set lifetime. Practical value. The experimental results confirm the possibility of extending the service life of cars after one-and-a-half life of their lifetime. The results of the work can be

  15. Changing Paradigm of Hemophilia Management: Extended Half-Life Factor Concentrates and Gene Therapy.

    Science.gov (United States)

    Kumar, Riten; Dunn, Amy; Carcao, Manuel

    2016-02-01

    Management of hemophilia has evolved significantly in the last century-from recognition of the causative mechanism in the 1950s to commercially available clotting factor concentrates in the 1960s. Availability of lyophilized concentrates in the 1970s set the stage for home-based therapy, followed by introduction of virally attenuated plasma-derived, and then recombinant factor concentrates in the 1980s and 1990s, respectively. The subsequent years saw a paradigm shift in treatment goals from on-demand therapy to prophylactic factor replacement starting at an early age, to prevent hemarthrosis becoming the standard of care for patients with severe hemophilia. In the developed world, the increasing use of home-based prophylactic regimens has significantly improved the quality of life, and life expectancy of patients with severe hemophilia. Seminal developments in the past 5 years, including the commercial availability of extended half-life factor concentrates and the publication of successful results of gene therapy for patients with hemophilia B, promise to further revolutionize hemophilia care over the next few decades. In this review, we summarize the evolution of management for hemophilia, with a focus on extended half-life factor concentrates and gene therapy. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  16. Ketone bodies mimic the life span extending properties of caloric restriction.

    Science.gov (United States)

    Veech, Richard L; Bradshaw, Patrick C; Clarke, Kieran; Curtis, William; Pawlosky, Robert; King, M Todd

    2017-05-01

    The extension of life span by caloric restriction has been studied across species from yeast and Caenorhabditis elegans to primates. No generally accepted theory has been proposed to explain these observations. Here, we propose that the life span extension produced by caloric restriction can be duplicated by the metabolic changes induced by ketosis. From nematodes to mice, extension of life span results from decreased signaling through the insulin/insulin-like growth factor receptor signaling (IIS) pathway. Decreased IIS diminishes phosphatidylinositol (3,4,5) triphosphate (PIP 3 ) production, leading to reduced PI3K and AKT kinase activity and decreased forkhead box O transcription factor (FOXO) phosphorylation, allowing FOXO proteins to remain in the nucleus. In the nucleus, FOXO proteins increase the transcription of genes encoding antioxidant enzymes, including superoxide dismutase 2, catalase, glutathione peroxidase, and hundreds of other genes. An effective method for combating free radical damage occurs through the metabolism of ketone bodies, ketosis being the characteristic physiological change brought about by caloric restriction from fruit flies to primates. A dietary ketone ester also decreases circulating glucose and insulin leading to decreased IIS. The ketone body, d-β-hydroxybutyrate (d-βHB), is a natural inhibitor of class I and IIa histone deacetylases that repress transcription of the FOXO3a gene. Therefore, ketosis results in transcription of the enzymes of the antioxidant pathways. In addition, the metabolism of ketone bodies results in a more negative redox potential of the NADP antioxidant system, which is a terminal destructor of oxygen free radicals. Addition of d-βHB to cultures of C. elegans extends life span. We hypothesize that increasing the levels of ketone bodies will also extend the life span of humans and that calorie restriction extends life span at least in part through increasing the levels of ketone bodies. An exogenous

  17. Combination of potassium sorbate and irradiation treatments to extend the shelf life of cured fish products

    International Nuclear Information System (INIS)

    Maha, M.; Sudarman, H.; Chosdu, R.; Siagian, E.G.

    1989-01-01

    Studies on shelf life extension of three kinds of cured fish products, i.e. salted chub mackeral (Rastrelliger neglectus), boiled chub mackerel (Rastrelliger neglectus) and smoked milkfish (Chanos chanos) have been made using a combined potassium sorbate and irradiation treatment. An integrated process for the preparation of each cured product provided with the combination treatment is described. Total bacterial count, total volatile base nitrogen, volatile reducing substances, and mould growth were used as objective indices of quality in comparison with sensory evaluation to determine the shelf life of the products held at ambient conditions. It was found that 0.1% potassium sorbate followed by irradiation up to 4 kGy retards mould growth on the products and extends the shelf life to a considerable length of time in comparison with the commercially prepared products. (author). 14 refs, 3 figs, 5 tabs

  18. Combination of potassium sorbate and irradiation treatments to extend the shelf-life cured fish products

    International Nuclear Information System (INIS)

    Maha, M.; Sudarman, H.; Chosdu, R.; Siagian, E.G.; Nasran, S.

    1981-01-01

    Studies on shelf-life extension of three kinds of cured fish product, i.e. salted chub mackerel (Rastrelliger neglectus), boiled chub mackerel (Rastrelliger neglectus) and smoked milkfish (Chanos chanos) have been done using a combined potassium sorbate and irradiation treatment. An integrated process for the preparation of each cured product provided with the combined treatment is described. Total bacterial count, total volatile base nitrogen, content of volatile reducing substances and mould growth were used as objective indices of quality in comparison with sensory evaluation to determine the shelf-life of the products held at ambient conditions. It was found that potassium sorbate residue of 0.1% level followed by irradiation up to 4 kGy could retard mould growth on the products and extend the shelf-life considerably in comparison with the commercially prepared products. (author)

  19. Similarities and differences among fluid milk products: traditionally produced, extended shelf life and ultrahigh-temperature processed.

    Science.gov (United States)

    Grabowski, N T; Ahlfeld, B; Brix, A; Hagemann, A; von Münchhausen, C; Klein, G

    2013-06-01

    Extended shelf life milk is a relatively new kind of fluid milk, generally manufactured by high-temperature treatment and/or micro-filtration. Being advertised as 'pasteurized milk with an extended shelf life', its flavour, compositional quality and labelling was questioned. Extended shelf life (high-temperature treatment), pasteurized ('traditionally produced') and ultrahigh-temperature milk were, therefore, compared at the beginning and end of shelf life. In triangle tests, panellists distinguished clearly between all products. High-temperature treatment milk's flavour was closer to ultrahigh-temperature and traditionally produced milk in the beginning and at the end of shelf life, respectively. Physicochemically and bacteriologically, all three types could be distinguished. Since 'extended shelf life' comprises many process varieties (each affecting flavour differently), consumer information and appropriate package labelling beyond 'long-lasting' is necessary, e.g. by mentioning the heat treatment applied.

  20. 33 CFR 149.550 - What are the requirements for lights on a floating hose string?

    Science.gov (United States)

    2010-07-01

    ... lights on a floating hose string? 149.550 Section 149.550 Navigation and Navigable Waters COAST GUARD... EQUIPMENT Aids to Navigation Lights on Floating Hose Strings § 149.550 What are the requirements for lights on a floating hose string? Hose strings that are floating or supported on trestles must display the...

  1. 33 CFR 183.530 - Spud, pipe, and hose fitting configuration.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Spud, pipe, and hose fitting....530 Spud, pipe, and hose fitting configuration. Except when used for a tank fill line, each spud, pipe, or hose fitting used with hose clamps must have: (a) A bead; (b) A flare; or (c) A series of annular...

  2. Resistive hose instability in the Bennet beam

    International Nuclear Information System (INIS)

    Nadezhdin, E.R.; Sorokin, G.A.

    1983-01-01

    Development of resistive hose instability of a relativistic electron beam with the Bennet current density distribution in a homogeneous unlimited plasma in the range of a high, 4πσ 0 a/c >> 1, and a low, 4πσ 0 a/c 0 =conductivity, c=light velocity, a = equilibrium beam radius) has been cansidered. Spatial and temporal increments of the instability development are calculated. In both cases the instability is of a convective nature. At 4πσ 0 a/c >> 1 the instability is shifted to the region of low frequencies as compared with the previously considered case of the Bennet profile of the plasma conductivity, σ(r)=σ 0 /(1+r 2 /a 2 ) 2 . It is shown that in an unlimited plasma a considerable decrease in the spatial and especially temporal increment of the instability development takes place

  3. Split mandrel versus split sleeve coldworking: Dual methods for extending the fatigue life of metal structures

    Science.gov (United States)

    Rodman, Geoffrey A.; Creager, Matthew

    1994-01-01

    It is common practice to use split sleeve coldworking of fastener holes as a means of extending the fatigue life of metal structures. In search of lower manufacturing costs, the aerospace industry is examining the split mandrel (sleeveless) coldworking process as an alternative method of coldworking fastener holes in metal structures. The split mandrel process (SpM) significantly extends the fatigue life of metal structures through the introduction of a residual compressive stress in a manner that is very similar to the split sleeve system (SpSl). Since the split mandrel process is significantly less expensive than the split sleeve process and more adaptable to robotic automation, it will have a notable influence upon other new manufacture of metal structures which require coldworking a significant number of holes, provided the aerospace community recognizes that the resulting residual stress distributions and fatigue life improvement are the same for both processes. Considerable testing has validated the correctness of that conclusion. The findings presented in this paper represent the results of an extensive research and development program, comprising data collected from over 400 specimens fabricated from 2024-T3 and 7075-T651 aluminum alloys in varied configurations, which quantify the benefits (fatigue enhancement and cost savings) of automating a sleeveless coldworking system.

  4. Ethylene Control Technologies in Extending Postharvest Shelf Life of Climacteric Fruit.

    Science.gov (United States)

    Zhang, Junhua; Cheng, Dong; Wang, Baobin; Khan, Iqbal; Ni, Yonghao

    2017-08-30

    Fresh fruit is important for a healthy diet. However, because of their seasonal production, regional specific cultivation, and perishable nature, it is essential to develop preservation technologies to extend the postharvest shelf life of fresh fruits. Climacteric fruit adopt spoilage because of ethylene, a key hormone associated with the ripening process. Therefore, controlling ethylene activity by following safe and effective approaches is a key to extend the postharvest shelf life of fruit. In this review, ethylene control technologies will be discussed aiming for the need of developing more innovative and effective approaches. The biosynthesis pathway will be given first. Then, the technologies determining the postharvest shelf life of climacteric fruit will be described with special attention to the latest and significant published works in this field. Special attention is given to 1-methylcyclopropene (1-MCP), which is effective in fruit preservation technologies. Finally, the encapsulation technology to improve the stability of 1-MCP will be proposed, using a potential encapsulation agent of 1-MCP, calixarene.

  5. Tools for in service monitoring and testing of riser to prevent failure and extend service life

    Energy Technology Data Exchange (ETDEWEB)

    Ward, Haakon; Bondevik, Jon Olav; Skjerve, Haavard; Tveit, Oeyvind [SeaFlex AS, Asker (Norway)

    2005-07-01

    Exploration and development of new oil and gas fields is heavily dependant on use of flexible pipes and many field developments would not have been possible without them. The number of flexible risers in service is constantly increasing since relatively few offshore projects have reached the estimated operational life and the operational lifetime of several fields in-service has been extended due to new and improved technology. Many risers have been in service over a large number of years. Some risers have been operated under demanding conditions such as severe dynamic loads, high pressure and temperatures. One may in some cases find that risers actually have shorter service life than estimated in the design phase due to the severe operational conditions. In order to extend the use of the riser, some risers may have to be modified and re-terminated and prepared for a new and less demanding application. In order to operate risers safely, it is important to re-assess the fatigue life in order to prevent potential riser failure. The operator should implement methods and tools for in-service monitoring and testing. This paper addresses efficient and reliable methods and tools for monitoring of critical operational parameters as well as in-service riser testing. A brief description of structural failure modes will also be given in order to understand how to interpret test results in view of potential failure modes. (author)

  6. Microbial biodiversity, quality and shelf life of microfiltered and pasteurized extended shelf life (ESL) milk from Germany, Austria and Switzerland.

    Science.gov (United States)

    Schmidt, Verena S J; Kaufmann, Veronika; Kulozik, Ulrich; Scherer, Siegfried; Wenning, Mareike

    2012-03-01

    Information on factors limiting the shelf life of extended shelf life (ESL) milk produced by microfiltration and subsequent pasteurization is very limited. In this study, three different batches of ESL milk were analyzed at different stages of the production process and during storage at 4 °C, 8 °C and 10 °C in order to evaluate the changes in bacterial cell counts, microbial diversity and enzymatic quality. Additionally, detailed biodiversity analyses of 250 retail ESL milk packages produced by five manufacturers in Germany, Austria and Switzerland were performed at the end of shelf life. It was observed that microfiltration decreased the microbial loads by 5-6 log₁₀ units to lower than 1 CFU/mL. However, bacterial counts at the end of shelf life were extremely variable and ranged between ESL treatment, causing stochastic variations of initial species distributions in individual packages. This would result in the development of significantly different bacterial populations during cold storage, including the occasional development of high numbers of pathogenic species such as B. cereus or Acinetobacter. Copyright © 2011 Elsevier B.V. All rights reserved.

  7. Extending shelf life of dithiothreitol-treated panel RBCs to 28 days.

    Science.gov (United States)

    Sigle, J-P; Mihm, B; Suna, R; Bargetzi, M

    2018-03-07

    Daratumumab (DARA) causes non-specific results in indirect agglutination testing (IAT). Dithiothreitol (DTT) treatment of panel red blood cells (RBCs) abolishes DARA interference. The objective of our study was to extend stability of DTT-treated panel RBCs to 28 days through application of a commercially available panel RBC stabilizer. Serological antigen typing and IAT using DARA sera and DARA plasma spiked with weakly reacting alloantibodies was performed up to 28 days after DTT treatment and stabilization. DTT treatment resulted in loss of Fy-antigen expression on some panel RBCs. Antigen profiles of stabilized, DTT-treated panel RBCs remained stable. Alloantibodies in DARA sera and DARA plasma were reliably detected. Application of a commercially available RBC stabilizer extends shelf life of DTT-treated panel RBCs to 28 days. © 2018 International Society of Blood Transfusion.

  8. Chitosan extends the shelf-life of filleted tilapia ( Oreochromis niloticus) during refrigerated storage

    Science.gov (United States)

    Cao, Rong; Liu, Qi; Yin, Bangzhong; Wu, Biao

    2012-09-01

    Shelf-life extension of aquatic products is of significant economical importance. To determine the potential effect of chitosan on the shelf-life of filleted tilapia, this study analyzed the bacterial community diversity in fresh and spoiled tilapia fillets stored at (4 ± 1)°C and examined the antimicrobial activity of chitosan against relevant bacteria isolates. Results showed that Pseudomonas (20%) and Aeromonas (16%) were abundant in fresh tilapia fillets, whereas Pseudomonas (52%), Aeromonas (32%) and Staphylococcus (12%) were dominant in the spoiled samples. Chitosan showed wide-spectrum antibacterial activity against bacteria isolated from tilapia and 5.0 g L-1 chitosan was selected for application in preservation. We further determined the shelf-life of chitosan-treated, filleted tilapia stored at (4 ± 1)°C based on microbiological, biochemical and sensory analyses. Results showed that the shelf-life of chitosan-treated, filleted tilapia was extended to 12 d, whereas that of untreated, control samples was 6 d. These indicate that chitosan, as a natural preservative, has great application potential in the shelf-life extension of tilapia fillets.

  9. Long term effects of extended adjuvant endocrine therapy on quality of life in breast cancer patients.

    Science.gov (United States)

    Kool, M; Fontein, D B Y; Meershoek-Klein Kranenbarg, E; Nortier, J W R; Rutgers, E J T; Marang-van de Mheen, P J; van de Velde, C J H

    2015-06-01

    The standard treatment for hormone-receptor positive, postmenopausal early breast cancer patients is 5 years of adjuvant endocrine therapy. Previous studies demonstrate that prolonging adjuvant endocrine therapy may improve disease-free survival. However, endocrine therapy is known for its adverse events, which may negatively affect Quality of Life (QoL). The aim of this study is to assess the impact of extended adjuvant endocrine therapy on long-term QoL outcomes. 471 patients selected from the IDEAL trial were invited to complete a questionnaire 1-1.5 years after starting with extended therapy. The questionnaire consisted of the EORTC QLQ-C30 and QLQ-BR23 questionnaires. Mean QoL outcomes were compared with EORTC reference values for stage I and II breast cancer patients and the general population. Furthermore, QoL outcomes were compared between different treatment regimens. A difference of eight points was considered clinically relevant. IDEAL patients receiving extended adjuvant endocrine therapy have significantly and clinically relevant better global QoL compared with reference values for stage I and II breast cancer patients (79.6 versus 64.6; p treatment regimens prior to extended adjuvant endocrine therapy, differences were only found on specific QoL domains (e.g. arm symptoms). Breast cancer patients on extended adjuvant endocrine therapy have significantly and clinically relevant better global QoL compared with other stage I-II breast cancer patients and the general population, 6-8.5 years after diagnosis. Copyright © 2015 Elsevier Ltd. All rights reserved.

  10. Performance Characterization of a Microchannel Liquid/Liquid Heat Exchanger Throughout an Extended Duration Life Test

    Science.gov (United States)

    Sheth, Rubik B.; Stephan, Ryan A.; Hawkins-Reynolds Ebony

    2011-01-01

    Liquid/Liquid Heat Exchangers (L/L HX) are an integral portion of any spacecraft active thermal control system. For this study the X-38 L/L HX was used as a baseline. As detailed in a previous ICES manuscript, NASA paired with Pacific Northwest National Laboratory to develop a Microchannel L/L HX (MHX). This microchannel HX was designed to meet the same performance characteristics as the aforementioned X-38 HX. The as designed Microchannel HX has a 26% and 60% reduction in mass and volume, respectively. Due to the inherently smaller flow passages the design team was concerned about fouling affecting performance during extended missions. To address this concern, NASA has developed a test stand and is currently performing an 18 month life test on the MHX. This report will detail the up-to-date performance of the MHX during life testing.

  11. Fatigue life prediction of casing welded pipes by using the extended finite element method

    Directory of Open Access Journals (Sweden)

    Ljubica Lazić Vulićević

    2016-03-01

    Full Text Available The extended finite element (XFEM method has been used to simulate fatigue crack growth in casing pipe, made of API J55 steel by high-frequency welding, in order estimate its structural integrity and life. Based on the critical value of stress intensity factor KIc, measured in different regions of welded joint, the crack was located in the base metal as the region with the lowest resistance to crack initiation and propagation. The XFEM was first applied to the 3 point bending specimens to verify numerical results with the experimental ones. After successful verification, the XFEM was used to simulate fatigue crack growth, position axially in the pipe, and estimate its remaining life.

  12. Mollusc-Microbe Mutualisms Extend the Potential for Life in Hypersaline Systems

    Science.gov (United States)

    Hickman, Carole S.

    2003-11-01

    Metazoans in extreme environments have evolved mutualisms with microbes that extend the physical and chemical capabilities of both partners. Some of the best examples are bivalve molluscs in evaporite and hypersaline settings. Mollusc tissue is developmentally and evolutionarily amenable to housing vast numbers of symbiotic microbes. Documented benefits to the host are nutritional. Multiple postulated benefits to the microbes are related to optimizing metabolic performance at interfaces, where heterogeneity and steep gradients that cannot be negotiated by microbes can be spanned by larger metazoan hosts. A small cockle, Fragum erugatum, and its photosymbiotic microbes provide a remarkable example of a mutualistic partnership in the hypersaline reaches of Shark Bay, Western Australia. Lucinid bivalves and their endosymbiotic chemolithotrophic bacteria provide examples in which hosts span oxic/anoxic interfaces on behalf of their symbionts at sites of seafloor venting. Multiple lines of evidence underscore the antiquity of mutualisms and suggest that they may have played a significant role in life's first experiments above the prokaryotic grade of complexity. The study of metazoan-microbe mutualisms and their signatures in extreme environments in the geologic record will provide a significant augmentation to microbial models in paleobiology and astrobiology. There are strong potential links between mutualisms and the early history of life on Earth, the persistence of life in extreme environments at times of global crisis and mass extinction, and the possibilities for life elsewhere in the universe.

  13. On-Board Real-Time Optimization Control for Turbo-Fan Engine Life Extending

    Science.gov (United States)

    Zheng, Qiangang; Zhang, Haibo; Miao, Lizhen; Sun, Fengyong

    2017-11-01

    A real-time optimization control method is proposed to extend turbo-fan engine service life. This real-time optimization control is based on an on-board engine mode, which is devised by a MRR-LSSVR (multi-input multi-output recursive reduced least squares support vector regression method). To solve the optimization problem, a FSQP (feasible sequential quadratic programming) algorithm is utilized. The thermal mechanical fatigue is taken into account during the optimization process. Furthermore, to describe the engine life decaying, a thermal mechanical fatigue model of engine acceleration process is established. The optimization objective function not only contains the sub-item which can get fast response of the engine, but also concludes the sub-item of the total mechanical strain range which has positive relationship to engine fatigue life. Finally, the simulations of the conventional optimization control which just consider engine acceleration performance or the proposed optimization method have been conducted. The simulations demonstrate that the time of the two control methods from idle to 99.5 % of the maximum power are equal. However, the engine life using the proposed optimization method could be surprisingly increased by 36.17 % compared with that using conventional optimization control.

  14. An integrated approach to extend the shelf life of a composite pastry product (cannoli).

    Science.gov (United States)

    Del Nobile, M A; Muratore, G; Conte, A; Incoronato, A L; Panza, O

    2009-12-01

    In this study, a combined approach is proposed to extend the shelf life of a composite pastry product (cannoli). In particular, to delay moisture migration, one, two, or three layers of a zein-based coating were studied. A three-layer coating represented the most effective solution to prevent rapid pastry softening. A subsequent experimental trial was aimed to prolong the shelf life of the ricotta-based stuffing. To this aim, two different antimicrobial compounds (lysozyme and lemon extract) at three concentrations (2,000, 3,000, and 4,000 ppm) were investigated separately from a microbiological and a sensorial point of view. Lemon extract was the active compound that received a better score, thus suggesting using 2,000 ppm of citrus extract in the last step. In the final experimental trial, cannoli were coated with three layers of zein, stuffed with ricotta containing the selected active agent, and packaged in two microperforated films. The use of zein-based coating and the lemon extract in the ricotta stuffing, combined with the barrier properties of the selected packaging materials, allowed a significant prolongation of cannoli shelf life, regardless of the type of film: a shelf life of more than 3 days was recorded, compared with the control samples, which were acceptable for less than 2 days. It is reasonable to assume that the proposed integrated approach could boost the distribution of the investigated typical pastry beyond local borders.

  15. Demagnetization monitoring and life extending control for permanent magnet-driven traction systems

    Science.gov (United States)

    Niu, Gang; Liu, Senyi

    2018-03-01

    This paper presents a novel scheme of demagnetization monitoring and life extending control for traction systems driven by permanent magnet synchronous motors (PMSMs). Firstly, the offline training is carried to evaluate fatigue damage of insulated gate bipolar transistors (IGBTs) under different flux loss based on first-principle modeling. Then an optimal control law can be extracted by turning down the power distribution factor of the demagnetizing PMSM until all damages of IGBTs turn to balance. Next, the similarity-based empirical modeling is employed to online estimate remaining flux of PMSMs, which is used to update the power distribution factor by referring the optimal control law for the health-oriented autonomous control. The proposed strategy can be demonstrated by a case study of traction drive system coupled with dual-PMSMs. Compared with traditional control strategy, the results show that the novel scheme can not only guarantee traction performance but also extend remaining useful life (RUL) of the system after suffering demagnetization fault.

  16. Are life-extending treatments for terminal illnesses a special case? Exploring choices and societal viewpoints.

    Science.gov (United States)

    McHugh, Neil; van Exel, Job; Mason, Helen; Godwin, Jon; Collins, Marissa; Donaldson, Cam; Baker, Rachel

    2017-12-16

    Criteria used by the National Institute for Health and Care Excellence (NICE) to assess life-extending, end-of-life (EoL) treatments imply that health gains from such treatments are valued more than other health gains. Despite claims that the policy is supported by societal values, evidence from preference elicitation studies is mixed and in-depth research has shown there are different societal viewpoints. Few studies elicit preferences for policies directly or combine different approaches to understand preferences. Survey questions were designed to investigate support for NICE EoL guidance at national and regional levels. These 'Decision Rule' and 'Treatment Choice' questions were administered to an online sample of 1496 UK respondents in May 2014. The same respondents answered questions designed to elicit their agreement with three viewpoints (previously identified and described) in relation to provision of EoL treatments for terminally ill patients. We report the findings of these choice questions and examine how they relate to each other and respondents' viewpoints. The Decision Rule questions described three policies: DA - a standard 'value for money' test, applied to all health technologies; DB - giving special consideration to all treatments for terminal illnesses; and DC - giving special consideration to specific categories of treatments for terminal illnesses e.g. life extension (as in NICE EoL guidance) or those that improve quality-of-life (QoL). Three Treatment Choices were presented: TA - improving QoL for patients with a non-terminal illness; TB - extending life for EoL patients; and TC - improving QoL at the EoL. DC received most support (45%) with most respondents giving special consideration to EoL only when treatments improved QoL. The most commonly preferred treatment choices were TA (51%) and TC (43%). Overall, this study challenges claims about public support for NICE's EoL guidance and the focus on life extension at EoL and substantiates

  17. LESSONS LEARNED IN OPERATING THE HOSE-IN-HOSE SYSTEM FOR TRANSFSERRING SLUDGE AT HANFORD'S K BASINS

    International Nuclear Information System (INIS)

    PERES MW

    2008-01-01

    In May 2007, the Department of Energy and the Fluor Hanford K Basin Closure Project completed transferring sludge from the K East Basin to new containers in the K West Basin using a Hose-in-Hose system. This project presented a number of complex and unique technical, operational, and management challenges that had to be resolved to complete the required transfers and satisfy project milestones. The project team (including DOE; regulators; and Fluor management, operations, maintenance, engineering and all other support organizations) found innovative solutions to each challenge. This paper records lessons learned during the operational phase of the sludge transfer via the Hose-In-Hose system. The subject is limited to the operational phase and does not cover design, development, testing or turnover. A discussion of the situation or problem encountered is provided, along with the lesson learned as applicable to a future program or project

  18. Second international symposium on nuclear power plant life management. Book of extended synopses

    International Nuclear Information System (INIS)

    2007-01-01

    The world's fleet of nuclear power plants is, on average, more than 20 years old. Even though the design life of a nuclear power plant is typically 30-40 years, it is quite feasible that many plants will be able to operate in excess of their design lives, provided that nuclear power plant engineers demonstrate by analysis, trending, equipment and system upgrades, increased vigilance, testing and ageing management that the plant will operate safely. In the operation of nuclear power plants, safety should be always the prime consideration. Plant operators and regulators must always ensure that plant safety is maintained, and where possible enhanced, during a plant's operating lifetime. Nuclear power plant life management (PLiM) has gained increased attention over the past decade, and effective ageing management of systems, structures and components (SSCs) is a key element in PLiM for the safe and reliable long term operation of nuclear power plants. A PLiM programme is an effective tool that allows an operator to safely and cost effectively manage ageing effects in SSCs. A PLiM programme helps to facilitate decisions concerning when and how to repair, replace or modify SSCs in an economically optimized way, while assuring that a high level of safety is maintained. The option for extended nuclear power plant operation has been recognized by operators and regulators alike, as evidenced in the number of licence renewal programmes that are being developed by Member States. The safe long term operation of nuclear power plants must also address non-physical ageing issues. A large portion of the qualified workforce will retire in the next few years, and it is essential to address this loss of expertise. Structured workforce planning is needed throughout the life of the plant in order to ensure that ageing of the workforce does not degrade plant safety and performance, and also in order that knowledge in utilities, regulatory bodies and contractors is effectively captured

  19. Use of Irradiation to Extend the Shelf Life of Dried White Oyster Mushroom (Pleurotus ostreatus)

    International Nuclear Information System (INIS)

    Idrus Kadir

    2010-01-01

    Irradiation is an alternative technology to extend the shelf life of food-stuffs. White oyster mushroom (Pleurotus ostreatus) which is a perishable food stuff having a short shelf life. Effects of gamma irradiation at the dose of 5 kGy on the quality of dried white oyster mushroom during storage was observed. The objective of the experiment was to improve the hygienic quality and to extend the shelf life of dried white oyster mushroom using irradiation technology. Fresh mushroom was cleaned, sorted, washed, and drained. The mushroom was then dried in two ways, namely: sun drying method and electrical oven drying method. Dried mushroom was vacuum packed in polypropylene (PP) pouch then irradiated at a of dose 5 kGy and an unirradiated control was also applied. The vacuum packed samples was stored at low temperature (18-20 o C) with a relative humidity (RH) of 65-70% and observed periodically every month up to 3 months of storage. The samples were analyzed according to the following parameters i.e, : total bacterial count, total mould and yeast count, moisture content, pH, a w , contents of protein, fat, carbohydrate, carotenoid and organoleptic properties, respectively. The results showed that irradiation at the dose of 5 kGy could eliminate significantly microbial growth 2 log cycle in the samples, while there were no changes in physico-chemical and organoleptic properties up to 3 months of storage, while control samples were still acceptable only up to 2 months of storage. (author)

  20. Vasoprotective effects of life span-extending peripubertal GH replacement in Lewis dwarf rats.

    Science.gov (United States)

    Ungvari, Zoltan; Gautam, Tripti; Koncz, Peter; Henthorn, Jim C; Pinto, John T; Ballabh, Praveen; Yan, Han; Mitschelen, Matthew; Farley, Julie; Sonntag, William E; Csiszar, Anna

    2010-11-01

    In humans, growth hormone deficiency (GHD) and low circulating levels of insulin-like growth factor 1 (IGF-1) significantly increase the risk for cerebrovascular disease. Genetic growth hormone (GH)/IGF-1 deficiency in Lewis dwarf rats significantly increases the incidence of late-life strokes, similar to the effects of GHD in elderly humans. Peripubertal treatment of Lewis dwarf rats with GH delays the occurrence of late-life stroke, which results in a significant extension of life span. The present study was designed to characterize the vascular effects of life span-extending peripubertal GH replacement in Lewis dwarf rats. Here, we report, based on measurements of dihydroethidium fluorescence, tissue isoprostane, GSH, and ascorbate content, that peripubertal GH/IGF-1 deficiency in Lewis dwarf rats increases vascular oxidative stress, which is prevented by GH replacement. Peripubertal GHD did not alter superoxide dismutase or catalase activities in the aorta nor the expression of Cu-Zn-SOD, Mn-SOD, and catalase in the cerebral arteries of dwarf rats. In contrast, cerebrovascular expression of glutathione peroxidase 1 was significantly decreased in dwarf vessels, and this effect was reversed by GH treatment. Peripubertal GHD significantly decreases expression of the Nrf2 target genes NQO1 and GCLC in the cerebral arteries, whereas it does not affect expression and activity of endothelial nitric oxide synthase and vascular expression of IGF-1, IGF-binding proteins, and inflammatory markers (tumor necrosis factor alpha, interluekin-6, interluekin-1β, inducible nitric oxide synthase, intercellular adhesion molecule 1, and monocyte chemotactic protein-1). In conclusion, peripubertal GH/IGF-1 deficiency confers pro-oxidative cellular effects, which likely promote an adverse functional and structural phenotype in the vasculature, and results in accelerated vascular impairments later in life.

  1. Extending Galactic Habitable Zone Modeling to Include the Emergence of Intelligent Life.

    Science.gov (United States)

    Morrison, Ian S; Gowanlock, Michael G

    2015-08-01

    Previous studies of the galactic habitable zone have been concerned with identifying those regions of the Galaxy that may favor the emergence of complex life. A planet is deemed habitable if it meets a set of assumed criteria for supporting the emergence of such complex life. In this work, we extend the assessment of habitability to consider the potential for life to further evolve to the point of intelligence--termed the propensity for the emergence of intelligent life, φI. We assume φI is strongly influenced by the time durations available for evolutionary processes to proceed undisturbed by the sterilizing effects of nearby supernovae. The times between supernova events provide windows of opportunity for the evolution of intelligence. We developed a model that allows us to analyze these window times to generate a metric for φI, and we examine here the spatial and temporal variation of this metric. Even under the assumption that long time durations are required between sterilizations to allow for the emergence of intelligence, our model suggests that the inner Galaxy provides the greatest number of opportunities for intelligence to arise. This is due to the substantially higher number density of habitable planets in this region, which outweighs the effects of a higher supernova rate in the region. Our model also shows that φI is increasing with time. Intelligent life emerged at approximately the present time at Earth's galactocentric radius, but a similar level of evolutionary opportunity was available in the inner Galaxy more than 2 Gyr ago. Our findings suggest that the inner Galaxy should logically be a prime target region for searches for extraterrestrial intelligence and that any civilizations that may have emerged there are potentially much older than our own.

  2. Cryonics suspension – debating life finitude, extending time capital and cancelling death

    Directory of Open Access Journals (Sweden)

    Oana Mara Stan

    2016-12-01

    Full Text Available The study discusses the anti-death movement inside the life extension paradigm and its social implications in terms of enhanced permeability of life-death boundaries, by reconciling mysticism, theology, technology and scientific innovation. It analyses current debates, the transmission of polemic information over extreme life extension by cryogenic suspension through vernacular knowledge. Ethical, scientific, financial and spiritual controversies come into consideration, as pro and counter-arguments emerge from ongoing debates investigated by netnography of themed blogs and forums. Digital platforms facilitate in-depth access to beliefs and attitudes expressed in relationship to continuity of stream of consciousness across the projected post-self project. The study calls for the questioning of agency and performativity in the context of transcending time dynamics and achieving biological and chronological time suspension. Solutions for extending longevity are explored in terms of critical reflection as to providers’ market, financial impact (e.g. creation of new niche products such as afterlife insurance to cover expenses of cryogenic suspension or fundraising for cryo-preserving young persons who died tragically and relocating the burden of proof in arguing whether human cryonics is potentially viable in the future. It brings a new perspective on the traceability and sustainability of time capital (Preda, 2013, while discussing the impact of the belief that death is ultimately curable and avoidable, by future medical progress and overall scientific and technological advancement.

  3. Extending the life-cycle of reverse osmosis membranes: A review.

    Science.gov (United States)

    Coutinho de Paula, Eduardo; Amaral, Míriam Cristina Santos

    2017-05-01

    The reverse osmosis (RO) technology for desalination and demineralization serves the global water crisis context, both technically and economically, and its market is growing. However, RO membranes have a limited life-cycle and are often disposed of in landfills. The impacts caused by the disposal of thousands of tonnes per annum of RO membranes have grown dramatically around the world. Waste prevention should have a high priority and take effect before the end-of-life phase of a product is reached. In this review, a summary is presented of the main advances in the performance of the RO technology and the membrane lifespan. Afterwards, this paper reviews the most important relevant literature and summarizes the key findings of the research on reusing and recycling the discarded modules for the purpose of extending the life-cycle of the RO membranes. In addtion, there are some recent researches that indicated recycling RO membranes for use by the microfiltration or ultrafiltration separation processes is a promising solution to the disposal problem. However, there are many gaps and differences in procedures and results. This article also discusses and brings to light key parameters involved and controversies about oxidative treatment of discarded RO membranes.

  4. Biofilms on Hospital Shower Hoses: Characterization and ...

    Science.gov (United States)

    Although the source of drinking water used in hospitals is commonly, biofilms on water pipelines are refuge to bacteria that survive different disinfection strategies. Drinking water (DW) biofilms are well known to harbor opportunistic pathogens, however, these biofilm communities remain poorly characterized by culture-independent approaches that circumvent the limitations of conventional monitoring efforts. Hence, the frequency of pathogens in DW biofilms and how biofilm members withstand high doses of disinfectants and/or chlorine residuals in the water supply remain speculative, but directly impact public health. The aim of this study was to characterize the composition of microbial communities growing on five hospital shower hoses using both culture-dependent and culture-independent techniques. Two different sequence-based methods were used to characterize the bacterial fractions: 16S rRNA gene sequencing of bacterial cultures and next generation sequencing of metagenomes. Based on the metagenomic data, we found that Mycobacterium-like species was the abundant bacterial taxa that overlapped among the five samples. We also recovered the draft genome of a novel Mycobacterium species, closely related to opportunistic pathogenic nontuberculous mycobacteria, M. rhodesiae and M. tusciae, in addition to other, less abundant species. In contrast, the cultured fraction was mostly affiliated to Proteobacteria, such as members of the Sphingomonas, Blastomonas and Porph

  5. Method using CO for extending the useful shelf-life of refrigerated red blood cells

    Science.gov (United States)

    Bitensky, Mark W.

    1995-01-01

    Method using CO for extending the useful shelf-life of refrigerated red blood cells. Carbon monoxide is utilized for stabilizing hemoglobin in red blood cells to be stored at low temperature. Changes observed in the stored cells are similar to those found in normal red cell aging in the body, the extent thereof being directly related to the duration of refrigerated storage. Changes in cell buoyant density, vesiculation, and the tendency of stored cells to bind autologous IgG antibody directed against polymerized band 3 IgG, all of which are related to red blood cell senescence and increase with refrigerated storage time, have been substantially slowed when red blood cells are treated with CO. Removal of the carbon monoxide from the red blood cells is readily and efficiently accomplished by photolysis in the presence of oxygen so that the stored red blood cells may be safely transfused into a recipient.

  6. PMR Extended Shelf Life Technology Given 2000 R and D 100 Award

    Science.gov (United States)

    Meador, Michael A.

    2001-01-01

    An approach developed at the NASA Glenn Research Center for extending the shelf life of PMR polyimide solutions and prepregs received an R&D 100 Award this year. PMR polyimides, in particular PMR-15, have become attractive materials for a variety of aerospace applications because of their outstanding high-temperature stability and performance. PMR-15 can be used in components with exposures to temperatures as high as 290 C, which leads to substantial reductions in weight, as much as 30 percent over metal components. PMR-15 composites are used widely in aerospace applications ranging from ducts and external components in aircraft engines to an engine access door for the Space Shuttle Main Engine. A major barrier to more widespread use of these materials is high component costs. Recent efforts at Glenn have addressed the various factors that contribute to these costs in an attempt to more fully utilize these lightweight, high-temperature materials.

  7. Isolation of human anti-serum albumin Fab antibodies with an extended serum-half life.

    Science.gov (United States)

    Kang, Hyeon-Ju; Kim, Hye-Jin; Cha, Sang-Hoon

    2016-01-01

    The serum albumin (SA) has been exploited to generate long-acting biotherapeutics by taking advantage of the FcRn-mediated recycling mechanism in a direct or an indirect way. Since Fab fragments have been proven to be clinically safe for human usage, we assumed that human anti-SA Fab antibodies could have a great potential as a carrier molecule to extend the serum half-life of therapeutic proteins. We, herein, had attempted to isolate anti-SA Fab antibodies from HuDVFab-8L antibody library via a phage display technology, and identified eight discrete human Fab antibodies. One of the Fab antibodies, SL335, showed the strongest binding reactivity to human SA with nM range of affinity at both pH 6 and pH 7.4, and cross-reacted to SAs from various species including rat, mouse, canine and monkey. The in vivo pharmacokinetic assay using a rat model indicated that SL335 has approximately 10 fold longer serum half-life and 26 to 44-fold increase in AUC0 → ∞ compared to the negative control Fab molecule in both intravenous and subcutaneous administrations. Knowing that Fabs have proven to be safe in clinics for a long time, SL335 seems to have a great potential in generating long-acting protein drugs by tagging effector molecules with either chemical conjugation or genetic fusion. Copyright © 2015 Elsevier B.V. All rights reserved.

  8. Interrupt-Based Step-Counting to Extend Battery Life in an Activity Monitor

    Directory of Open Access Journals (Sweden)

    Seung Young Kim

    2016-01-01

    Full Text Available Most activity monitors use an accelerometer and gyroscope sensors to characterize the wearer’s physical activity. The monitor measures the motion by polling an accelerometer or gyroscope sensor or both every 20–30 ms and frequent polling affects the battery life of a wearable device. One of the key features of a commercial daily-activity monitoring device is longer battery life so that the user can keep track of his or her activity for a week or so without recharging the battery of the monitoring device. Many low-power approaches for a step-counting system use either a polling-based algorithm or an interrupt-based algorithm. In this paper, we propose a novel approach that uses the tap interrupt of an accelerometer to count steps while consuming low power. We compared the accuracy of step counting and measured system-level power consumption to a periodic sensor-reading algorithm. Our tap interrupt approach shows a battery lifetime that is 175% longer than that of a 30 ms polling method without gyroscope. The battery lifetime can be extended up to 863% with a gyroscope by putting both the processor and the gyroscope into sleep state during the majority of operation time.

  9. Apparatus and methods for splicing conduits and hoses subsea

    Energy Technology Data Exchange (ETDEWEB)

    Slocum, Alexander Henry; Gutierrez, Luis Javier

    2014-03-11

    A hose connection system comprises a body including an internal cavity and a port in fluid communication with a portion of the internal cavity. In addition, the system comprises a hose end fitting positioned in the cavity. The hose end fitting includes an inner tubular member and an outer tubular member concentrically disposed about the inner tubular member. The outer tubular member includes a plurality of circumferentially spaced axial slits. Further, the system comprises a plurality of wedge members arranged circumferentially about the outer tubular member. Still further, the system comprises an annular piston movably disposed within the internal cavity of the body. An end of the piston has an inner frustoconical surface that slidingly engages the plurality of wedge members. The piston is configured to move axially through the body and compress the wedge members and the outer tubular member radially inward.

  10. Hose-Modulation Instability of Laser Pulses in Plasmas

    International Nuclear Information System (INIS)

    Sprangle, P.; Krall, J.; Esarey, E.

    1994-01-01

    A laser pulse propagating in a uniform plasma or a preformed plasma density channel is found to undergo a combination of hose and modulation instabilities, provided the pulse centroid has an initial tilt. Coupled equations for the laser centroid and envelope are derived and solved for a finite-length laser pulse. Significant coupling between the centroid and the envelope, harmonic generation in the envelope, and strong modification of the wake field can occur. Methods to reduce the growth rate of the laser hose instability are demonstrated

  11. Ensuring microbiological safety and extending the shelf life of shelled sweet corn kernels using hurdle technology

    International Nuclear Information System (INIS)

    Kumar, Sanjeev; Gautam, Satyendra

    2015-01-01

    Shelled sweet corn kernels are prone to microbial contaminations due to high moisture and nutrient contents. Post harvest handling further aggravates the condition and makes the product highly perishable and unsafe. In freshly shelled kernels total aerobic plate count, yeast mold count and presumptive coliforms were found to be ∼ 8, 7, and 4 log cfu/g, respectively. IMViC analysis confirmed presence of opportunistic pathogens like Escherichia coli and Enterobacteraerogenes in these samples. Besides, occurrence of mycotoxin such as ochratoxin A (OTA), classified as a possible carcinogenic compound, was found to be high in sweet corn samples spiked with toxigenic strain. To address this issue, a combination process including NaOCl washing (200 ppm for 5 min), hot water blanching (60℃ for 5 min), air drying, LDPE packaging, and finally gamma radiation (5 kGy) treatment was developed. The developed combination process was found to reduce microbial load to below detectable level and quite effectively inactivated Aspergillusochraceus spores as well as pre-formed toxin. These treatments were not found to affect the contents of biochemical constituents such as total and reducing sugars, proteins, phenolics, and flavonoids during storage. Prophylactic properties in terms of antioxidant capacity and potential to suppress chemical induced mutagenesis were not affected in these samples. Physical properties and sensory qualities were also found to be similar to fresh (control). Thus, the developed combination process ensured microbiological safety and extended shelf life of sweet corn kernels up to 30 days at 4℃ . (author)

  12. A Fasting-Responsive Signaling Pathway that Extends Life Span in C. elegans

    Directory of Open Access Journals (Sweden)

    Masaharu Uno

    2013-01-01

    Full Text Available Intermittent fasting is one of the most effective dietary restriction regimens that extend life span in C. elegans and mammals. Fasting-stimulus responses are key to the longevity response; however, the mechanisms that sense and transduce the fasting stimulus remain largely unknown. Through a comprehensive transcriptome analysis in C. elegans, we find that along with the FOXO transcription factor DAF-16, AP-1 (JUN-1/FOS-1 plays a central role in fasting-induced transcriptional changes. KGB-1, one of the C. elegans JNKs, acts as an activator of AP-1 and is activated in response to fasting. KGB-1 and AP-1 are involved in intermittent fasting-induced longevity. Fasting-induced upregulation of the components of the SCF E3 ubiquitin ligase complex via AP-1 and DAF-16 enhances protein ubiquitination and reduces protein carbonylation. Our results thus identify a fasting-responsive KGB-1/AP-1 signaling pathway, which, together with DAF-16, causes transcriptional changes that mediate longevity, partly through regulating proteostasis.

  13. Use Of Irradiation To Extend The Shelf Life Of Meat Luncheon And Ensure Its Microbiological Safety

    International Nuclear Information System (INIS)

    Hammad, A. A. I.; Zahran, D.; Attalla, S.

    2004-01-01

    The microbiological quality of meat luncheon sold in retail market at Cairo was evaluated E. coli was found in all tested samples (25 samples), Staphylococcus aureus was found in 23 (92%) samples, Salmonella was detected in only 2 (8%) samples, Aeromonas hydrophila was detected in only 1 (4%) samples. Listeria monocytogenes was not detected in any sample. According to the Egyptian standards, meat luncheon should be free from the above pathogens. Thus, only 2 (8%) samples of examined meat luncheon were accepted from the view point of microbiological quality. Irradiation at different dose levels used (1.5, 3.0, 5.0 kGy) greatly reduced all microbial counts, hence extended the shelf-life of meat luncheon at 4 deg. C ± 1 to 2, 3 and 4 weeks, respectively, against only 1 week of the unirradiated samples. Only meat luncheon samples irradiated at 5.0 kGy were free from all tested pathogens indicating that this irradiation dose was very effective in insuring microbial safety of meat luncheon. (Authors)

  14. Use of edible films and coatings to extend the shelf life of food products.

    Science.gov (United States)

    Maftoonazad, Neda; Badii, Fojan

    2009-06-01

    The increased consumer demand for high quality, extended shelf life, ready to eat foods has initiated the development of several innovative techniques to keep their natural and fresh appearance as long as possible and at the same time render them safe. Packaging has been an important element in these preservation concepts for providing the appropriate (mechanical and functional) protection to the commodity. Since synthetic packaging materials contribute to the environmental pollution, edible coatings and packages have been proposed to replace or complement conventional packaging. Biodegradable and edible films and coatings are made from naturally occurring polymers and functional ingredients, and formed on the surface of food products. Edible films and coating have long been known to protect perishable food products from deterioration and reduce quality loss. These films should have acceptable sensory characteristics, appropriate barrier properties (CO(2), O(2), water, oil), microbial, biochemical and physicochemical stability, they should be safe, and be produced by simple technology in low cost. Also they can act as effective carrier for antioxidant, flavor, color, nutritional or anti-microbial additives. Patents on edible films and food products are also discussed in this article.

  15. An extended family suddenly confronted with a life-threatening hereditary arrhythmia.

    Science.gov (United States)

    Hendriks, K S W H; van Langen, I M; van Tintelen, J P; Grosfeld, F J M; Wilde, A A M; Ten Kroode, H F J

    2005-09-01

    This exploratory study serves to illustrate the psychological impact on an extended family in the process of genetic counselling and testing for a potentially life-threatening arrhythmia, the long-QT syndrome (LQTS). All members of the third generation and their partners (n=11) were interviewed, the mutation carriers with partners twice. In addition they completed measures for anxiety and depression three times in 18 months. During the interviews these family members emphasised the damaged solidarity when the family is divided into carriers and noncarriers of a mutation in a LQTS predisposing gene. This demonstrates one way in which a family can react to the reality of being at risk of a potentially severe disease. Rewriting family history and mourning early death seem other ways to deal with this. The distress scores, especially of the women, were moderate to clinically high, not because of their own chance of having an arrhythmia but more due to their children's risk. Mothers need educational even more than emotional support, because the lifestyle of their carrier children is in need of radical change. The setting of a combined outpatient cardiogenetic clinic with a medical and psychosocial staff meets such needs efficiently.

  16. Collaborative machining solution extends the operating life of a nuclear power plant

    International Nuclear Information System (INIS)

    Gilmore, Geoff; Becker, Andrew; Vandenberg, James

    2007-01-01

    Examination of a CANDU 6 nuclear power plant's steam generators during a scheduled maintenance outage revealed that the manway ports, part of the ASME Section III, Class 1 pressure boundary, needed repair. The port's inner cover gasket was not seating properly. Integrity was at risk. It was determined that this operation would required a specialized machine to successfully repair the manway port. The solution included the modification of a standard portable boring machine with a custom mounting option to enlarge the counterbore in the primary head shell from a round shape to an obround shape (76 mm of shell thickness, 16 mm radially). The shape change was needed to accommodate the new obround cover and gasket seal design. Once the new major shape was machined, the repair was finished with a Computer Numerically Controlled (CNC) machine developed by the service team to achieve the necessary gasket face location and sizing. The final result met all of the plant's expectations and was completed well within the time allotted during the maintenance shut down. This success was due to the positive partnership and collaboration of the service team and the machine tool manufacture working together to successfully extend the operating life of the nuclear power plant. (author)

  17. 46 CFR 32.50-30 - Cargo hose-TB/ALL.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Cargo hose-TB/ALL. 32.50-30 Section 32.50-30 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS SPECIAL EQUIPMENT, MACHINERY, AND HULL REQUIREMENTS Pumps, Piping, and Hose for Cargo Handling § 32.50-30 Cargo hose—TB/ALL. Cargo hose carried on...

  18. 49 CFR 178.348-3 - Pumps, piping, hoses and connections.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Pumps, piping, hoses and connections. 178.348-3... FOR PACKAGINGS Specifications for Containers for Motor Vehicle Transportation § 178.348-3 Pumps, piping, hoses and connections. Each pump and all piping, hoses and connections on each cargo tank motor...

  19. 49 CFR 178.337-9 - Pressure relief devices, piping, valves, hoses, and fittings.

    Science.gov (United States)

    2010-10-01

    ..., and fittings. 178.337-9 Section 178.337-9 Transportation Other Regulations Relating to Transportation....337-9 Pressure relief devices, piping, valves, hoses, and fittings. (a) Pressure relief devices. (1... encountered. (b) Piping, valves, hose, and fittings. (1) The burst pressure of all piping, pipe fittings, hose...

  20. Why are women more likely than men to extend paid work? The impact of work-family life history.

    Science.gov (United States)

    Finch, Naomi

    2014-03-01

    Extending working life beyond the state pension age is a key European Union policy. In the UK, women are more likely to extend paid work than men, indicating that factors other than the state pension age play a role in working longer. Women are less able to build pension income due to their role as carer within the family. It, therefore, follows that gender inequalities over the life course continue into older age to influence need, capacity and desire to undertake paid work after state pension age. This paper explores how work, marital and fertility history impact upon the likelihood of extending employment. It uses the British Household Panel Survey's retrospective data from the first 14 waves to summarise work-family histories, and logistic regression to understand the impact of work and family histories on extending paid work. Findings show that, on the one hand, women are extending paid work for financial reasons to make up for 'opportunity costs' as a result of their caring role within the family, with short breaks due to caring, lengthy marriages, divorcing and remaining single with children all being important. Yet, there is also evidence of 'status maintenance' from working life, with the women most likely to extend paid work, also those with the highest work orientation, prior to state pension age. But lengthy dis-attachment (due to caring) from the labour market makes extending working life more difficult. This has implications for policy strategies to entice women into paid work to make up for low independent financial resources.

  1. Objective 1: Extend Life, Improve Performance, and Maintain Safety of the Current Fleet; Implementation Plan

    International Nuclear Information System (INIS)

    Youngblood, Robert

    2011-01-01

    Nuclear power has reliably and economically contributed almost 20% of electrical generation in the United States over the past two decades. It remains the single largest contributor (more than 70%) of non-greenhouse-gas-emitting electric power generation in the United States. By the year 2030, domestic demand for electrical energy is expected to grow to levels of 16 to 36% higher than 2007 levels. At the same time, most currently operating nuclear power plants will begin reaching the end of their 60 year operating licenses. Figure E 1 shows projected nuclear energy contribution to the domestic generating capacity. If current operating nuclear power plants do not operate beyond 60 years, the total fraction of generated electrical energy from nuclear power will begin to decline - even with the expected addition of new nuclear generating capacity. The oldest commercial plants in the United States reached their 40th anniversary in 2009. The U.S. Department of Energy Office of Nuclear Energy's Research and Development (R and D) Roadmap has organized its activities in accordance with four objectives that ensure nuclear energy remains a compelling and viable energy option for the United States. The objectives are as follows: (1) develop technologies and other solutions that can improve the reliability, sustain the safety, and extend the life of the current reactors; (2) develop improvements in the affordability of new reactors to enable nuclear energy to help meet the Administration's energy security and climate change goals; (3) develop sustainable nuclear fuel cycles; and (4) understand and minimize risks of nuclear proliferation and terrorism. The Light Water Reactor Sustainability (LWRS) Program is the primary programmatic activity that addresses Objective 1. This document describes how Objective 1 and the LWRS Program will be implemented. The existing U.S. nuclear fleet has a remarkable safety and performance record and today accounts for 70% of the low greenhouse

  2. Objective 1: Extend Life, Improve Performance, and Maintain Safety of the Current Fleet Implementation Plan

    Energy Technology Data Exchange (ETDEWEB)

    Robert Youngblood

    2011-02-01

    Nuclear power has reliably and economically contributed almost 20% of electrical generation in the United States over the past two decades. It remains the single largest contributor (more than 70%) of non-greenhouse-gas-emitting electric power generation in the United States. By the year 2030, domestic demand for electrical energy is expected to grow to levels of 16 to 36% higher than 2007 levels. At the same time, most currently operating nuclear power plants will begin reaching the end of their 60 year operating licenses. Figure E 1 shows projected nuclear energy contribution to the domestic generating capacity. If current operating nuclear power plants do not operate beyond 60 years, the total fraction of generated electrical energy from nuclear power will begin to decline—even with the expected addition of new nuclear generating capacity. The oldest commercial plants in the United States reached their 40th anniversary in 2009. The U.S. Department of Energy Office of Nuclear Energy’s Research and Development (R&D) Roadmap has organized its activities in accordance with four objectives that ensure nuclear energy remains a compelling and viable energy option for the United States. The objectives are as follows: (1) develop technologies and other solutions that can improve the reliability, sustain the safety, and extend the life of the current reactors; (2) develop improvements in the affordability of new reactors to enable nuclear energy to help meet the Administration’s energy security and climate change goals; (3) develop sustainable nuclear fuel cycles; and (4) understand and minimize risks of nuclear proliferation and terrorism. The Light Water Reactor Sustainability (LWRS) Program is the primary programmatic activity that addresses Objective 1. This document describes how Objective 1 and the LWRS Program will be implemented. The existing U.S. nuclear fleet has a remarkable safety and performance record and today accounts for 70% of the low greenhouse

  3. Objective 1: Extend Life, Improve Performance, and Maintain Safety of the Current Fleet Implementation Plan

    Energy Technology Data Exchange (ETDEWEB)

    Robert Youngblood

    2011-01-01

    Nuclear power has reliably and economically contributed almost 20% of electrical generation in the United States over the past two decades. It remains the single largest contributor (more than 70%) of non-greenhouse-gas-emitting electric power generation in the United States. By the year 2030, domestic demand for electrical energy is expected to grow to levels of 16 to 36% higher than 2007 levels. At the same time, most currently operating nuclear power plants will begin reaching the end of their 60 year operating licenses. Figure E 1 shows projected nuclear energy contribution to the domestic generating capacity. If current operating nuclear power plants do not operate beyond 60 years, the total fraction of generated electrical energy from nuclear power will begin to decline—even with the expected addition of new nuclear generating capacity. The oldest commercial plants in the United States reached their 40th anniversary in 2009. The U.S. Department of Energy Office of Nuclear Energy’s Research and Development (R&D) Roadmap has organized its activities in accordance with four objectives that ensure nuclear energy remains a compelling and viable energy option for the United States. The objectives are as follows: (1) develop technologies and other solutions that can improve the reliability, sustain the safety, and extend the life of the current reactors; (2) develop improvements in the affordability of new reactors to enable nuclear energy to help meet the Administration’s energy security and climate change goals; (3) develop sustainable nuclear fuel cycles; and (4) understand and minimize risks of nuclear proliferation and terrorism. The Light Water Reactor Sustainability (LWRS) Program is the primary programmatic activity that addresses Objective 1. This document describes how Objective 1 and the LWRS Program will be implemented. The existing U.S. nuclear fleet has a remarkable safety and performance record and today accounts for 70% of the low greenhouse

  4. Effect of Temperature and Hose Genotype on Components of ...

    African Journals Online (AJOL)

    Effect of Temperature and Hose Genotype on Components of Resistance to Groundnut Rust. ... African Crop Science Journal ... The effects of temperature on incubation period, infection frequency, lesion diameter, leaf area damage, pustule rupture, and sporulation were quantified for six groundnut genotypes, representing ...

  5. Integrity and efficiency in LNG transfer operations with flexible hoses

    NARCIS (Netherlands)

    Bokhorst, E. van; Twerda, A.

    2014-01-01

    The work presented contributes to the LNG supply chain by the development of a validated calculation model for corrugated flexible hoses or pipes developed for LNG Transfer. The model builds upon experience gained by TNO Technical Sciences (Fluid Dynamics) in a large number of flow tests carried out

  6. 49 CFR 571.106 - Standard No. 106; Brake hoses.

    Science.gov (United States)

    2010-10-01

    ...) Maintain a compressed air supply to the nozzle or nozzles free of oil and dirt and between 10 and 25 psi... SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR VEHICLE SAFETY STANDARDS Federal Motor Vehicle Safety Standards § 571.106 Standard No. 106; Brake hoses. S1. Scope. This standard specifies...

  7. 33 CFR 183.540 - Hoses: Standards and markings.

    Science.gov (United States)

    2010-07-01

    ...) SAE Standard J1527DEC85, Class 1 and the fire test in § 183.590; or (2) Underwriters' Laboratories... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Hoses: Standards and markings. 183.540 Section 183.540 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY...

  8. Oblique electron fire hose instability: Particle-in-cell simulations

    Czech Academy of Sciences Publication Activity Database

    Hellinger, Petr; Trávníček, Pavel M.; Decyk, V.; Schriver, D.

    2014-01-01

    Roč. 119, č. 1 (2014), s. 59-68 ISSN 2169-9380 R&D Projects: GA ČR GAP209/12/2041 Institutional support: RVO:67985815 Keywords : electron temperature anisotropy * fire hose instability Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics Impact factor: 3.426, year: 2014

  9. 46 CFR 197.456 - Breathing supply hoses.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Breathing supply hoses. 197.456 Section 197.456 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE OCCUPATIONAL SAFETY AND HEALTH STANDARDS GENERAL PROVISIONS Commercial Diving Operations Periodic Tests and Inspections of Diving Equipment § 197...

  10. California condors spotted nesting in Big Spur | San Hose Mercury ...

    African Journals Online (AJOL)

    California condors spotted nesting in Big Spur. Associated Press San Hose Mercury News. Abstract. No Abstract. Vulture News Vol. 55, 2006: 59. Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · AJOL African Journals Online. HOW TO USE AJOL.

  11. Assessing integrity and realiability of multicomposite LNG transfer hoses

    NARCIS (Netherlands)

    Weijde, G.D. van der; Putten, S. van der

    2012-01-01

    Reliable transfer systems are a key element in developing floating LNG and the small scale LNG market. Multi-composite hoses may prove to be a reliable and cost effective solution for offshore, near- and on-shore applications. TNO, the Dutch contract research organization, has executed an extensive

  12. Need for consent of a law extending the operating life of nuclear power plants

    International Nuclear Information System (INIS)

    Degenhart, Christoph

    2010-01-01

    The article deals with the question whether a law extending nuclear power plant life beyond the residual periods of time laid down in the law of April 22, 2002 requires consent of the Federal Council. The Atomic Energy Act needed the consent of the Federal Council pursuant to Article 87c, Basic Law, as its Section 24 determines that central functions of licensing and supervision be exercised by the federal states on behalf of the Federal Government. This has not changed after the current version of the norm. Increasing the residual quotas of electricity by amending Annex 3 of Sec.7, Para.1a, Atomic Energy Act, per se does not require consent. This is a substantive provision. Sec.24, Atomic Energy Act, does not need to be amended. The Federal Council, which consented to the original legislation, thus does not bear continued responsibility for the law. Every law must be treated as a separate entity in terms of legislative method. The Federal Council, with its first consent to the piece of legislation, ''approves'' this systemic shift. Renewed consent is required only in case of another systemic shift. This is the case when the provision about administrative responsibility takes on a very different meaning and impact no longer supported by the earlier consent. According to decisions by the Federal Constitutional Court, this expressly applies also to administration by commission. What is required is a comparison of administrative duties before and after entry into force of the amending law; mere quantitative shifts of administrative burdens do not cause a systemic shift. Whether the inclusion of backfitting obligations would be associated with regulations in administrative procedures has not been decided. In its ruling of May 4, 2010, the Federal Constitutional Court confirms that these do not require consent within the framework of Art.85 Para.1, Basic Law. (orig.)

  13. Evaluation of a Modified Atmosphere Packaging System to Increase Fresh Fruit and Vegetable Shelf Life for Extended Military Supply Chains

    Science.gov (United States)

    2012-02-24

    STORAGE STABILITY LOGISTICS MANAGEMENT SUPPLIES LETTUCE AFGHANISTAN FOOD SERVICE MAP( MODIFIED ATMOSPHERE ...chain. This technology is a case level modified atmosphere packaging system (MAPS). The evaluation included three produce items – iceberg lettuce ... MODIFIED ATMOSPHERE PACKAGING SYSTEM TO INCREASE FRESH FRUIT AND VEGETABLE SHELF LIFE FOR EXTENDED MILITARY SUPPLY CHAINS 5a. CONTRACT NUMBER 5b

  14. Pre-Clinical Intravenous Serum Pharmacokinetics of Albumin Binding and Non-Half-Life Extended Nanobodies®

    Directory of Open Access Journals (Sweden)

    Sven Hoefman

    2015-07-01

    Full Text Available Nanobodies are antigen-binding, single variable domain proteins derived from naturally-occurring, heavy chain only antibodies. They are highly soluble, stable, and can be linked to build multi-specific formats. Several Nanobodies are currently in clinical development in different therapeutic areas, for both chronic and acute applications. For the former, prolonged exposure is achieved by half-life extending moieties that target endogenous albumin, while for the latter, non-half-life extended constructs are preferable. To demonstrate the general pharmacokinetic behavior of both formats, serum levels of seven intravenously administered Nanobodies were analyzed in cynomolgus monkeys, mice or rabbits. In monkeys, the total clearance of a monomeric irrelevant Nanobody was rapid (2.0 mL/(min*kg and approximated the species glomerular filtration rate, indirectly suggesting that the Nanobody was mainly eliminated via the kidneys. When linked to an anti-albumin Nanobody, a 376-fold decrease in clearance was observed, resulting in a terminal half-life of 4.9 days, corresponding to the expected species albumin half-life. Similar conclusions were drawn for (non- half-life extended mono-, bi- and trimeric Nanobodies in mice or rabbits, suggesting that these kinetic principles apply across species. Applying this knowledge to species translation and study design is crucial for successful pre-clinical development of novel therapeutic Nanobody candidates.

  15. Metabotypes with properly functioning mitochondria and anti-inflammation predict extended productive life span in dairy cows

    Science.gov (United States)

    Huber, K.; Dänicke, S.; Rehage, J.; Sauerwein, H.; Otto, W.; Rolle-Kampczyk, U.; von Bergen, M.

    2016-01-01

    The failure to adapt metabolism to the homeorhetic demands of lactation is considered as a main factor in reducing the productive life span of dairy cows. The so far defined markers of production performance and metabolic health in dairy cows do not predict the length of productive life span satisfyingly. This study aimed to identify novel pathways and biomarkers related to productive life in dairy cows by means of (targeted) metabolomics. In a longitudinal study from 42 days before up to 100 days after parturition, we identified metabolites such as long-chain acylcarnitines and biogenic amines associated with extended productive life spans. These metabolites are mainly secreted by the liver and depend on the functionality of hepatic mitochondria. The concentrations of biogenic amines and some acylcarnitines differed already before the onset of lactation thus indicating their predictive potential for continuation or early ending of productive life. PMID:27089826

  16. International symposium on nuclear power plant life management. Book of extended synopses

    International Nuclear Information System (INIS)

    2002-01-01

    A number of nuclear power plants in operation are meeting the problems of aging. Besides maintaining safety and reliability many NPP owners are concerned with service life extension, life management policy, and reactor maintenance procedures. The topics covered in this report are devoted to: NPP life management, economics and technical aspects of service life extension, reactor licensing procedures; aging of reactor components; physical radiation effects on reactor materials; corrosion; mechanical properties of reactor materials; reactor control systems; reactor safety systems

  17. Quality of Life Indicators for Individuals with Intellectual Disabilities: Extending Current Practice

    Science.gov (United States)

    Brown, Ivan; Hatton, Chris; Emerson, Eric

    2013-01-01

    Quality of life is a social construct that is measured by what are considered to be its most appropriate indicators. Quality of life measurement in intellectual disability reflects a variety of indicators, often grouped under life domains. Subjective and objective methods of measuring indicators each have strengths and drawbacks, but it is…

  18. Ozonated water extends the shelf life of fresh-cut lettuce.

    Science.gov (United States)

    Beltrán, David; Selma, María V; Marín, Alicia; Gil, María I

    2005-07-13

    The use of ozonated water as a sanitizer to extend the shelf life of fresh-cut lettuce and the effect on the antioxidant constituents (polyphenols and vitamin C) were investigated. Fresh-cut iceberg lettuce (Lactuca sativa L.) was washed at 4 degrees C using three different ozonated water dips [10, 20, and 10 activated by ultraviolet C (UV-C) light mg L(-1) min total ozone dose], and the dips were compared with water and chlorine rinses. Treated lettuce was packaged in air or active modified atmosphere packaging (MAP) (4 kPa of O2 + 12 kPa of CO2 balanced with N2) and stored for 13 days at 4 degrees C. Despite its strong oxidizing activity, ozonated water did not stimulate the respiratory activity of fresh-cut lettuce. Moreover, ozonated water maintained the initial visual appearance of fresh-cut lettuce and controlled browning during storage in air. Initially, ozonated water and chlorine reduced the total mesophilic population by 1.6 and 2.1 log, respectively, when compared with water. Active MAP was effective in controlling total microbial growth, achieving 2.0 log reduction in relation to samples stored in air at the end of storage. On the other hand, active MAP caused a 2.0-3.5 reduction of coliforms on sanitized samples compared with water-washed samples. The most efficient treatments were ozone 20 and ozone 10 activated by UV-C, which were as effective as chlorine. Changes in individual phenolic compounds were independent of the washing treatments. In air, chlorogenic and isochlorogenic acid contents increased noticeably after 13 days while monocaffeoyltartaric and dicaffeoyltartaric acids remained unchanged. MAP effectively suppressed accumulation of caffeoylquinic derivatives, whereas caffeoyltartaric derivatives decreased during MAP storage to reach similar levels. The content of vitamin C (ascorbic acid and dehydroascorbic acid) decreased during storage, particularly under MAP. Ozonated water could be an alternative sanitizer to chlorine for fresh

  19. Use of irradiation in combination with preservation techniques to extend the shelf-life of tropical fruits and their products

    International Nuclear Information System (INIS)

    Noomhorm, A.; Ilangantileke, S.G.; Upadhyay, I.P.; Karki, D.B.; Apintanapong, M.

    1998-01-01

    Gamma irradiation in combination with other treatment processes was investigated with a view to extending the shelf-life of some tropical fruits in fresh and processed conditions. A low dose of irradiation (0.6 kGy) combined with hot water treatment (at 55 deg. C for 20 min) extended the shelf-life of fresh mangoes from 15 to 32 days at 20 deg. C storage. The shelf-life of fresh lychees was extended to 16 days by irradiation (1 kGy) and storage at 5 deg. C through reducing the rotting and preserving the fruit colour. A shelf-life of up to 30 days was obtained by a combination of hot benomyl dipping of the lychess (at 55 deg. C for 2 min) and polyethylene packaging, whereas modified atmosphere storage in CO 2 did not control pericarp browning. Irradiation as a means of preservation was investigated in processed fruits such as semi-dried mangoes and longans, and mango puree. A minimum dose of 2 kGy extended the shelf-life of the semi-dried mangoes and longans for up to 75 days when stored at 14 deg. C, without mould growth, whereas these fruits deteriorated at 30 deg. C storage, as indicated by discoloration and a deterioration in the flavour. On the other hand, doses of up to 4 kGy and storage at a low temperature (5 deg. C) were necessary to maintain microorganism growth (as determined by the aerobic plate count) at the lowest level; no microorganisms were observed at 6 kGy and higher. The chemical attributes of the puree tended to remain unaffected by the irradiation treatment but were more sensitive to the storage duration and conditions. The puree was preserved for as long as 60 days at 5 deg. C, without compromising the keeping quality. (author)

  20. Application of ESL (Extended Shelf Life) Technology in Drinking Milk Production

    OpenAIRE

    ÜNVER, Naciye; ÇELİK, Şerafettin

    2017-01-01

    Nowadays pasteurization andUHT are the best known and most commonly used technologies in milk production.While products which have shorter shelf life and fresh taste are obtained byusing pasteurization, products which have longer shelf life but less desirabletaste are obtained by UHT technology. ESL technology is a new method which wasdeveloped to obtain a longer shelf life product than pasteurized milk andbetter sensory quality product than UHT milk. ESL milk includes technologiessuch as mic...

  1. A study on the functional assessment of the prestressed system and main structural elements in life extended containment building

    International Nuclear Information System (INIS)

    Cheong, C. H.; Kim, S. W.; Choi, J. G.

    2001-10-01

    The design life of KNGR (Korean Next Generation Reactor) containment buildings is extended from 40 years to 60 years. However, nuclear reactor buildings are passive structures that are impossible to be exchanged in the case of degradation by the deterioration and so on when extending the design life of structures. Therefore, it is necessary to consider the long-term safety endurance in the design and construction of KNGR. Also, ti is judged that choice of the material and various test methods should be prescribed clearly. In this study, the reduction schemes of deterioration and the safety-ensuring schemes are drawn for the expected performance to be maintained from the beginning of the service to the required period together with ensuring the safety and serviceability of KNGR which will be constructed with the design life of 60 years, taking into account the dimensions, selection of material and construction methods in the design and construction stages. Also, the validity is to be examined for the estimation method of long-term losses of stress introduced to KNGR whose design life is increased to 60 years. The durability enhancement scheme on the design and construction for the design life extension of nuclear containment buildings is to be drawn through these studies. These results are utilized as the basic data for the safety inspection and examination guides of KNGR and finally the additional investigations are proposed for the items which require long-term studies

  2. A study on the functional assessment of the prestressed system and main structural elements in life extended containment building

    Energy Technology Data Exchange (ETDEWEB)

    Cheong, C. H.; Kim, S. W.; Choi, J. G. [DAEWOO E and C Institute of Costruction Technology, Suwon (Korea, Republic of)] (and others)

    2001-10-15

    The design life of KNGR (Korean Next Generation Reactor) containment buildings is extended from 40 years to 60 years. However, nuclear reactor buildings are passive structures that are impossible to be exchanged in the case of degradation by the deterioration and so on when extending the design life of structures. Therefore, it is necessary to consider the long-term safety endurance in the design and construction of KNGR. Also, ti is judged that choice of the material and various test methods should be prescribed clearly. In this study, the reduction schemes of deterioration and the safety-ensuring schemes are drawn for the expected performance to be maintained from the beginning of the service to the required period together with ensuring the safety and serviceability of KNGR which will be constructed with the design life of 60 years, taking into account the dimensions, selection of material and construction methods in the design and construction stages. Also, the validity is to be examined for the estimation method of long-term losses of stress introduced to KNGR whose design life is increased to 60 years. The durability enhancement scheme on the design and construction for the design life extension of nuclear containment buildings is to be drawn through these studies. These results are utilized as the basic data for the safety inspection and examination guides of KNGR and finally the additional investigations are proposed for the items which require long-term studies.

  3. Simulations of the Ion-Hose Instability for DARHT-II Long-Pulse Experiments

    CERN Document Server

    Chan, K C D

    2004-01-01

    Ion-hose effect has been described extensively in literatures. Computer simulations of the effect typically use particle-in-cell (PIC) computer codes or codes using the spread-mass formulation [1]. PIC simulations, though offering more reliable results, will require extended running time in large computers To support commissioning experiments in the DARHT-II induction linac in Los Alamos National Laboratory, we have modified a spread-mass code so that we can survey quickly the parameter space for the experiment. It can also be used to provide quick answers during experiment. The code was originally written by Genoni from Mission Research Corporation (MRC) for constant linac parameters. We have modified it so that parameters can have dependence along the length of the linac. In this paper, we will describe simulation results using this code for the DARHT-II commissioning experiment and also our benchmarking results comparing to LSP, a PIC code from MRC.

  4. Oblique electron fire hose instability: Particle-in-cell simulations

    Czech Academy of Sciences Publication Activity Database

    Hellinger, Petr; Trávníček, Pavel M.; Decyk, V.; Schriver, D.

    2014-01-01

    Roč. 119, č. 1 (2014), s. 59-68 ISSN 2169-9380 R&D Projects: GA ČR GAP209/12/2041 Grant - others:European Commission(XE) 284515 Institutional support: RVO:68378289 Keywords : electron temperature anisotropy * fire hose instability Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 3.426, year: 2014 http://onlinelibrary.wiley.com/doi/10.1002/2013JA019227/abstract

  5. Extended Aging Theories for Predictions of Safe Operational Life of Critical Airborne Structural Components

    Science.gov (United States)

    Ko, William L.; Chen, Tony

    2006-01-01

    The previously developed Ko closed-form aging theory has been reformulated into a more compact mathematical form for easier application. A new equivalent loading theory and empirical loading theories have also been developed and incorporated into the revised Ko aging theory for the prediction of a safe operational life of airborne failure-critical structural components. The new set of aging and loading theories were applied to predict the safe number of flights for the B-52B aircraft to carry a launch vehicle, the structural life of critical components consumed by load excursion to proof load value, and the ground-sitting life of B-52B pylon failure-critical structural components. A special life prediction method was developed for the preflight predictions of operational life of failure-critical structural components of the B-52H pylon system, for which no flight data are available.

  6. Extending conceptual frameworks: life course epidemiology for the study of back pain

    Directory of Open Access Journals (Sweden)

    Dunn Kate M

    2010-02-01

    Full Text Available Abstract Background Epidemiological studies have identified important causal and prognostic factors for back pain, but these frequently only identify a proportion of the variance, and new factors add little to these models. Recently, interest has increased in studying diseases over the life course, stimulated by the 1997 book by Kuh and Ben-Shlomo, a move accompanied by important conceptual and methodological developments. This has resulted in improvements in the understanding of other conditions like cardiovascular and respiratory disease. This paper aims to examine how conceptual frameworks from life course epidemiology could enhance back pain research. Discussion Life course concepts can be divided into three categories. Concept 1: patterns over time, risk chains and accumulation. Simple 'chains of risk' have been studied - e.g. depression leading to back pain - but studies involving more risk factors in the chain are infrequent. Also, we have not examined how risk accumulation influences outcome, e.g. whether multiple episodes or duration of depression, throughout the life course, better predicts back pain. One-year back pain trajectories have been described, and show advantages for studying back pain, but there are few descriptions of longer-term patterns with associated transitions and turning points. Concept 2: influences and determinants of pathways. Analyses in back pain studies commonly adjust associations for potential confounders, but specific analysis of factors modifying risk, or related to the resilience or susceptibility to back pain, are rarely studied. Concept 3: timing of risk. Studies of critical or sensitive periods - crucial times of life which influence health later in life - are scarce in back pain research. Such analyses could help identify factors that influence the experience of pain throughout the life course. Summary Back pain researchers could usefully develop hypotheses and models of how risks from different stages

  7. Specific inhibition of Photobacterium phosphoreum extends the shelf life of modified-atmosphere-packed cod fillets

    DEFF Research Database (Denmark)

    Dalgaard, Paw; Munoz, L.G.; Mejlholm, Ole

    1998-01-01

    Inhibition of the specific spoilage organism, Photobacterium phosphoreum, was studied in model substrates and in modified- atmosphere-packed cod fillets. The objective was to determine how inhibition of this organism influenced spoilage. The spoilage reactions limiting shelf life were studied...... rather than the development of a new product. In naturally contaminated modified-atmosphere-packed cod fillets, 500 ppm Na(2)CaEDTA reduced the growth rate of P. phosphoreum by 40% and shelf life was increased proportionally by 40%, from 15 to 17 days to 21 to 23 days at 0 degrees C. In aerobically...... stored cod fillets other microorganisms were responsible for spoilage and Na2CaEDTA had no effect on shelf Life. The extension of the shelf life of modified-atmosphere-packed cod therefore was a result of the reduced growth of P. phosphoreum and no other microbial or nonmicrobial spoilage reactions...

  8. Does having children extend life span? A genealogical study of parity and longevity in the Amish.

    Science.gov (United States)

    McArdle, Patrick F; Pollin, Toni I; O'Connell, Jeffrey R; Sorkin, John D; Agarwala, Richa; Schäffer, Alejandro A; Streeten, Elizabeth A; King, Terri M; Shuldiner, Alan R; Mitchell, Braxton D

    2006-02-01

    The relationship between parity and life span is uncertain, with evidence of both positive and negative relationships being reported previously. We evaluated this issue by using genealogical data from an Old Order Amish community in Lancaster, Pennsylvania, a population characterized by large nuclear families, homogeneous lifestyle, and extensive genealogical records. The analysis was restricted to the set of 2,015 individuals who had children, were born between 1749 and 1912, and survived until at least age 50 years. Pedigree structures and birth and death dates were extracted from Amish genealogies, and the relationship between parity and longevity was examined using a variance component framework. Life span of fathers increased in linear fashion with increasing number of children (0.23 years per additional child; p =.01), while life span of mothers increased linearly up to 14 children (0.32 years per additional child; p =.004) but decreased with each additional child beyond 14 (p =.0004). Among women, but not men, a later age at last birth was associated with longer life span (p =.001). Adjusting for age at last birth obliterated the correlation between maternal life span and number of children, except among mothers with ultrahigh (>14 children) parity. We conclude that high parity among men and later menopause among women may be markers for increased life span. Understanding the biological and/or social factors mediating these relationships may provide insights into mechanisms underlying successful aging.

  9. 46 CFR 58.30-20 - Fluid power hose and fittings.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Fluid power hose and fittings. 58.30-20 Section 58.30-20... MACHINERY AND RELATED SYSTEMS Fluid Power and Control Systems § 58.30-20 Fluid power hose and fittings. (a... § 58.30-1. (b) Hose and fittings shall meet the requirements of subpart 56.60 of this subchapter. (c...

  10. Vacuum Drying for Extending Litchi Shelf-Life: Vitamin C, Total Phenolics, Texture and Shelf-Life Assessment.

    Science.gov (United States)

    Richter Reis, Felipe; de Oliveira, Aline Caroline; Gadelha, Gabriella Giani Pieretti; de Abreu, Marcela Breves; Soares, Hillary Isabelle

    2017-06-01

    In an attempt to obtain shelf-stable litchi fruit with preserved nutritional quality and good sensory features, quarters of peeled and pitted fruits were vacuum dried at 50, 60 and 70 °C at a constant pressure of 8.0 kPa. The product was assessed for its vitamin C, total phenolics and texture (hardness). In addition, the product with the best texture was assessed for its shelf-life by means of accelerated testing. Results suggest that vacuum dried litchi retained almost 70% of the vitamin C and total phenolics when compared to frozen fruits (control). Vitamin C and phenolic compounds content significantly decreased with drying, while no difference was found between different drying temperatures. Hardness increased with drying temperature. The sample dried at 70 °C presented crispness, which is a desired quality feature in dried fruit products. This sample was subjected to shelf-life evaluation, whose result suggests a shelf-life of eight months at 23 °C. Total color change (CIE ΔE 00 ) was the expiry criterion. Vacuum drying was a suitable technique for producing shelf-stable litchi fruit with good texture while preserving its desirable original nutrients. Consumption of vacuum dried litchi may be beneficial to health due to its remarkable content of phenolic compounds and vitamin C.

  11. STS-32 crewmembers use water hoses during fire fighting training at JSC

    Science.gov (United States)

    1989-01-01

    STS-32 crewmembers use water hoses during fire fighting exercises at JSC's Fire Training Pit across from the Gilruth Center Bldg 207. Mission Specialist (MS) G. David Low with nozzle open directs water into the fire as fire/ security personnel coaches and instructs him on his attempt to extinguish the blaze. MS Bonnie J. Dunbar maneuvers the hose behind Low. A second group of crewmembers alongside Low and Dunbar, MS Marsha S. Ivins, holding hose nozzle, Commander Daniel C. Brandenstein, and Pilot James D. Wetherbee position themselves before opening hose nozzle.

  12. Ignition of PTFE-lined flexible hoses by rapid pressurization with oxygen

    Science.gov (United States)

    Janoff, Dwight; Bamford, Larry J.; Newton, Barry E.; Bryan, Coleman J.

    1989-01-01

    A high-volume pneumatic-impact system has been used to test PTFE-lined stainless steel braided hoses, in order to characterize the roles played in the mechanism of oxygen-induced ignition by impact pressure, pressurization rate, and upstream and downstream volumes of the hose. Ignitions are noted to have occurred at impact pressures well below the working pressure of the hoses, as well as at pressurization rates easily obtainable through manual operation of valves. The use of stainless steel hardlines downstream of the hose prevented ignitions at all pressures and pressurization rates; internal observations have shown evidence of shock ionization in the oxygen prior to ignition.

  13. Use of Reactor Pressure Vessel Surveillance Materials for Extended Life Evaluations Using Power and Test Reactor Irradiations

    International Nuclear Information System (INIS)

    Server, W.L.; Nanstad, R.K.; Odette, G.R.

    2012-01-01

    The most important component in assuring safety of the nuclear power plant is the reactor pressure (RPV). Surveillance programs have been designed to cover the licensed life of operating nuclear RPVs. The original surveillance programs were designed when the licensed life was 40 years. More than one-half of the operating nuclear plants in the USA have an extended license out to 60 years, and there are plans to continue to operate many plants out to 80 years. Therefore, the surveillance programs have had to be adjusted or enhanced to generate key data for 60 years, and now consideration must be given for 80 or more years. To generate the necessary data to assure safe operation out to these extended license lives, test reactor irradiations have been initiated with key RPV and model alloy steels, which include several steels irradiated in the current power reactor surveillance programs out to relatively high fluence levels. These data are crucial in understanding the radiation embrittlement mechanisms and to enable extrapolation of the irradiation effects on mechanical properties for these extended time periods. This paper describes the potential radiation embrittlement mechanisms and effects when assessing much longer operating times and higher neutron fluence levels. Potential methods for adjusting higher neutron flux test reactor data for use in predicting power reactor vessel conditions are discussed. (author)

  14. TO THE ISSUE OF EXTENDING THE SERVICE LIFE OF CARS FOR TRANSPORTATION OF PELLETS

    OpenAIRE

    V. H. Anofriev; O. H. Reidemeister; V. A. Kalashnyk; V. P. Kulieshov

    2016-01-01

    Purpose. Freight rolling stock of «Ukrzaliznytsia» primarily has cars that are overaged. The same situation is observed in the park of specialized cars. So the car fleet for the transport of pellets consists of about 50% of cars that served one-and-a-half and more lifetimes. However, the volume of shipments of iron ore is constant for a number of years. In this regard, there is a need to find methods to justify continuing useful life of cars and to assess the conformity of residual life of th...

  15. Reflective Writing and Life-Career Planning: Extending the Learning in a Learning Community Model

    Science.gov (United States)

    Nownes, Nicholas; Stebleton, Michael

    2010-01-01

    This essay recounts the authors' experiences as community college faculty members in a learning community (LC) linking first-year composition with a class in life-career planning and development. The authors begin with a learning community story shared recently over drinks with a group of community college English teachers. They use the story to…

  16. More Education May Limit Disability and Extend Life For People With Cognitive Impairment.

    Science.gov (United States)

    Laditka, Sarah B; Laditka, James N

    2014-08-01

    Education is associated with longer life and less disability. Living longer increases risks of cognitive impairment, often producing disability. We examined associations among education, disability, and life expectancy for people with cognitive impairment, following a 1992 cohort ages 55+ for 23 063 person-years (Panel Study of Income Dynamics, n = 2165). We estimated monthly probabilities of disability and death for 7 education levels, adjusting for age, gender, ethnicity, and cognitive status. We used the probabilities to simulate populations with age-specific cognitive impairment incidence and monthly disability status through death. For those with cognitive impairment, education was associated with longer life and less disability. Among them, college-educated white women lived 3.2 more years than those with education, disabled 24.4% of life from age 55 compared with 36.7% (Peducation will lengthen lives. Living longer, more people will have cognitive impairment. Education may limit their risk of disability and its duration. © The Author(s) 2014.

  17. Extending the shelf life of flower bulbs and perennials in consumer packages by modiefied atmosphere packaging

    NARCIS (Netherlands)

    Gude, H.; Dijkema, M.H.G.E.; Miller, C.T.

    2011-01-01

    The quality of flower bulbs and herbaceous perennials in consumer packages declines rapidly due to sprouting and drying out. The present study was undertaken to develop Modified Atmosphere Packages (MAP) with suitable filling materials for a prolonged shelf life of different species of flower bulbs

  18. A Comparison Study: The New Extended Shelf Life Isopropyl Ester PMR Technology versus The Traditional Methyl Ester PMR Approach

    Science.gov (United States)

    Alston, William B.; Scheiman, Daniel A.; Sivko, Gloria S.

    2005-01-01

    Polymerization of Monomeric Reactants (PMR) monomer solutions and carbon cloth prepregs of PMR II-50 and VCAP-75 were prepared using both the traditional limited shelf life methanol based PMR approach and a novel extended shelf life isopropanol based PMR approach. The methyl ester and isopropyl ester based PMR monomer solutions and PMR prepregs were aged for up to four years at freezer and room temperatures. The aging products formed were monitored using high pressure liquid chromatography (HPLC). The composite processing flow characteristics and volatile contents of the aged prepregs were also correlated versus room temperature storage time. Composite processing cycles were developed and six ply cloth laminates were fabricated with prepregs after various extended room temperature storage times. The composites were then evaluated for glass transition temperature (Tg), thermal decomposition temperature (Td), initial flexural strength (FS) and modulus (FM), long term (1000 hours at 316 C) thermal oxidative stability (TOS), and retention of FS and FM after 1000 hours aging at 316 C. The results for each ester system were comparable. Freezer storage was found to prevent the formation of aging products for both ester systems. Room temperature storage of the novel isopropyl ester system increased PMR monomer solution and PMR prepreg shelf life by at least an order of magnitude while maintaining composite properties.

  19. Strategies to Extend Bread and GF Bread Shelf-Life: From Sourdough to Antimicrobial Active Packaging and Nanotechnology

    Directory of Open Access Journals (Sweden)

    Valentina Melini

    2018-02-01

    Full Text Available Bread is a staple food worldwide. It commonly undergoes physico-chemical and microbiological changes which impair its quality and shelf-life. Staling determines organoleptic impairment, whereas microbiological spoilage causes visible mould growth and invisible production of mycotoxins. To tackle this economic and safety issue, the bakery industry has been working to identify treatments which allow bread safety and extended shelf-life. Physical methods and chemical preservatives have long been used. However, new frontiers have been recently explored. Sourdough turned out an ancient but novel technology to preserve standard and gluten-free bread. Promising results have also been obtained by application of alternative bio-preservation techniques, including antifungal peptides and plant extracts. Active packaging, with absorbing and/or releasing compounds effective against bread staling and/or with antimicrobials preventing growth of undesirable microorganisms, showed up an emerging area of food technology which can confer many preservation benefits. Nanotechnologies are also opening up a whole universe of new possibilities for the food industry and the consumers. This work thus aims to provide an overview of opportunities and challenges that traditional and innovative anti-staling and anti-spoilage methods can offer to extend bread shelf-life and to provide a basis for driving further research on nanotechnology applications into the bakery industry.

  20. The life of a dead ant -the expression of an adaptive extended phenotype

    DEFF Research Database (Denmark)

    Andersen, Sandra Breum; Gerritsma, Sylvia; Yusah, Kalsum M.

    2009-01-01

    Specialized parasites are expected to express complex adaptations to their hosts. Manipulation of host behavior is such an adaptation. We studied the fungus Ophiocordyceps unilateralis, a locally specialized parasite of arboreal Camponotus leonardi ants. Ant-infecting Ophiocordyceps are known...... to make hosts bite onto vegetation prior to killing them. We show that this represents a fine-tuned fungal adaptation: an extended phenotype. Dead ants were found under leaves, attached by their mandibles, on the northern side of saplings ca. 25 cm above the soil, where temperature and humidity conditions...

  1. Factor Activity Assays for Monitoring Extended Half-Life FVIII and Factor IX Replacement Therapies.

    Science.gov (United States)

    Kitchen, Steve; Tiefenbacher, Stefan; Gosselin, Robert

    2017-04-01

    The advent of modified factor VIII (FVIII) and factor IX (FIX) molecules with extended half-lives (EHLs) compared with native FVIII and FIX represents a major advance in the field of hemophilia care, with the potential to reduce the frequency of prophylactic injections and/or to increase the trough level prior to subsequent injections. Monitoring treatment through laboratory assays will be an important part of ensuring patient safety, including any tailoring of prophylaxis. Several approaches have been used to extend half-lives, including PEGylation, and fusion to albumin or immunoglobulin. Some of these modifications affect factor assays as routinely performed in hemophilia centers; so, laboratories will need to use FVIII and FIX assays which have been shown to be suitable on a product-by-product basis. For some products, there are marked differences between results obtained using one-stage or chromogenic assays and results obtained using different reagents in the one-stage assay. The laboratory should use an assay in which the recovery of the product closely aligns with the assay used by the pharmaceutical company to assign potency to the product, so that the units reported by the laboratory agree with those used to demonstrate efficacy of the product during clinical trials. Reported assay differences in relation to several of the EHL FVIII and FIX molecules will be reviewed in this article. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  2. Bowel function and quality of life after superior mesenteric nerve plexus transection in right colectomy with D3 extended mesenterectomy.

    Science.gov (United States)

    Thorsen, Y; Stimec, B; Andersen, S N; Lindstrom, J C; Pfeffer, F; Oresland, T; Ignjatovic, D

    2016-07-01

    The aim of this study was to ascertain the impact of injury to the superior mesenteric nerve plexus caused by right colectomy with D3 extended mesenterectomy as performed in the prospective multicenter trial: "Safe Radical D3 Right Hemicolectomy for Cancer through Preoperative Biphasic Multi-detector Computed Tomography" in which all soft tissue surrounding the superior mesenteric vessels from the level of the middle colic artery to that of the ileocolic artery was removed. Bowel function and gastrointestinal quality of life in two consecutive cohorts that underwent right colectomy with and without D3 extended mesenterectomy were compared. Main outcome measures were the Diarrhea Assessment Scale (DAS) and Gastrointestinal Quality of Life Index (GIQLI). The data were collected prospectively through telephone interviews. Forty-nine patients per group, comparable for age, sex, length of bowel resected but with significantly shorter follow-up time in the experimental group, were included. There was no difference in total DAS scores, subscores or additional questions except for higher bowel frequency scores in the D3 group (p = 0.02). Comparison of total GIQLI scores and subscales showed no difference between groups. Regression analysis with correction for confounding factors showed 0.48 lower bowel frequency scores in the D2 group (p = 0.022). Within the D3 group presence of jejunal arteries cranial to the D3 dissection area showed 1.78 lower DAS scores and 0.7 lower bowel frequency scores. Small bowel denervation after right colectomy with D3 extended mesenterectomy leads to increased bowel frequency but does not impact gastrointestinal quality of life. Individual anatomical variants can affect postoperative bowel function differently despite standardized surgery.

  3. Method for extending the useful shelf-life of refrigerated red blood cells by flushing with inert gas

    Science.gov (United States)

    Bitensky, M.W.; Yoshida, Tatsuro

    1997-04-29

    A method is disclosed using oxygen removal for extending the useful shelf-life of refrigerated red blood cells. A cost-effective, 4 C storage procedure that preserves red cell quality and prolongs post-transfusion in vivo survival is described. Preservation of adenosine triphosphate levels and reduction in hemolysis and in membrane vesicle production of red blood cells stored at 4 C for prolonged periods of time is achieved by removing oxygen from the red blood cells at the time of storage; in particular, by flushing with an inert gas. Adenosine triphosphate levels of the stored red blood cells are boosted in some samples by addition of ammonium phosphate. 4 figs.

  4. Method for extending the useful shelf-life of refrigerated red blood cells by flushing with inert gas

    Science.gov (United States)

    Bitensky, Mark W.; Yoshida, Tatsuro

    1997-01-01

    Method using oxygen removal for extending the useful shelf-life of refrigerated red blood cells. A cost-effective, 4.degree. C. storage procedure that preserves red cell quality and prolongs post-transfusion in vivo survival is described. Preservation of adenosine triphosphate levels and reduction in hemolysis and in membrane vesicle production of red blood cells stored at 4.degree. C. for prolonged periods of time is achieved by removing oxygen therefrom at the time of storage; in particular, by flushing with an inert gas. Adenosine triphosphate levels of the stored red blood cells are boosted in some samples by addition of ammonium phosphate.

  5. Efficacy of Various Preservatives on Extending Shelf Life of Vacuum-Packaged Raw Pork during 4°C Storage.

    Science.gov (United States)

    Yang, Chao; Qi, Yan; Zheng, Jiayi; Fan, X U; Liang, Peixin; Song, Cunjiang

    2018-04-01

    Uncontrolled bacterial growth and metabolic activities are responsible for the short shelf life of raw pork. Culture-independent analysis by 16S ribosome cDNA could reveal viable bacteria in raw pork. This study investigated microbial growth and volatile organic compounds of raw pork supplemented with various preservatives. Vacuum-packaged raw pork was stored at 4°C, after soaking in solutions of potassium sorbate, ε-poly-l-lysine, kojic acid (KA), or sodium diacetate, individually. Spoilage of raw pork was monitored by determining pH and total volatile basic nitrogen, whereas bacterial growth was determined by culture-dependent and culture-independent analyses. Data indicated that all the preservatives were able to inhibit bacterial growth and extend the shelf life of pork. High-throughput sequencing of 16S ribosome cDNA indicated that Pseudomonas was inhibited under vacuum conditions, whereas facultative anaerobes ( Acinetobacter, Photobacterium, Brochothrix, and Myroides) were the most active genera in the spoiled pork. Photobacterium was further inhibited by each preservative. The inhibition of Acinetobacter, Photobacterium, and Myroides could be responsible for the extended shelf life of vacuum-packaged pork; they were effectively inhibited by KA, which also induced the longest shelf life. Moreover, 19 types of volatile organic compounds were detected. 3-Methylbutanol, 3-methylbutanol acetate, 2-butanone, toluene, benzeneacetaldehyde, dimethyl trisulfide, and acetoin were associated with spoilage. Furthermore, KA is a potential preservative in raw pork; because no phenol was detectable within 35 days, excessive intake of phenol induced by preservatives was avoided.

  6. Proton fire hose instabilities in the expanding solar wind

    Czech Academy of Sciences Publication Activity Database

    Hellinger, Petr

    2017-01-01

    Roč. 83, č. 1 (2017), č. článku 705830105. ISSN 0022-3778 Institutional support: RVO:68378289 Keywords : astrophysicals plasmas * plasma expansion * plasma simulation Subject RIV: BL - Plasma and Gas Discharge Physics OBOR OECD: Fluids and plasma physics (including surface physics) Impact factor: 1.160, year: 2016 https://www.cambridge.org/core/journals/journal-of-plasma-physics/article/proton-fire-hose-instabilities-in-the-expanding-solar-wind/6BA70378B25728533588A1A68073AC2F

  7. Extending the shelf life of fresh sweet corn by shrink-wrapping, refrigeration, and irradiation

    International Nuclear Information System (INIS)

    Deak, T.

    1987-01-01

    Chemical, physical, sensory, and microbiological changes were monitored during storage of unwrapped and shrink-wrapped fresh sweet corn at 10 degree and 20 degree C. Wrapping essentially eliminated moisture loss and resulted in elevated carbon dioxide and decreased oxygen concentrations within packages. These effects, together with refrigeration markedly reduced the changes associated with senscence and post harvest deterioration, and hence resulted in at least a threefold extension in shelf life. The water-saturated atmosphere, however, enhanced microbial growth on shrink-wrapped corn. The initial microbial population was effectively decreased by treating the wrapped corn with 0.5 or 1.0 kGy (Co 60 ) irradiation

  8. The role of NDE in maintaining and extending the life cycle of engineering components

    International Nuclear Information System (INIS)

    Doctor, S.R.

    1997-01-01

    A successful life cycle of engineering components begins during the design to select the best materials for a given application, designing for economical maintenance, and accommodating NDE inspections. NDE in the nuclear industry is part of the defense in depth to insure structural integrity of components. High reliability NDE is needed to reliably detect and accurately characterize the failure modes that have occurred in nuclear components. The move toward risk-informed inservice inspection programs focusses the NDE on the most safety significant components. The use of performance demonstration testing is leading to improved inservice inspections through screening out ineffective procedure/equipment/personnel. (orig.)

  9. Technical Evaluation for the Determination of CGI Designation for Safety Class Items Incorporated in Hose-in-Hose Transfer Line Assemblies

    Energy Technology Data Exchange (ETDEWEB)

    BUCHANAN, J.R.

    2000-05-16

    The purpose of this technical evaluation is to determine whether the secondary hoses are to be categorized as Commercial Grade Items (CGI) or Engineered Equipment. This determination will identify whether or not use of the CGI Dedication process is appropriate.

  10. Technical Evaluation for the Determination of CGI Designation for Safety Class Items Incorporated in Hose-in-Hose Transfer Line Assemblies

    International Nuclear Information System (INIS)

    BUCHANAN, J.R.

    2000-01-01

    The purpose of this technical evaluation is to determine whether the secondary hoses are to be categorized as Commercial Grade Items (CGI) or Engineered Equipment. This determination will identify whether or not use of the CGI Dedication process is appropriate

  11. Extended interface layer concept for higher stability and improvement of life time in bulk heterojunction solar cells

    Directory of Open Access Journals (Sweden)

    Farman Ali

    2015-02-01

    Full Text Available Power conversion efficiency (PCE of bulk heterojunction (BHJ organic solar cells has reached above ∼10%. These BHJ cells have potential for flexible thin films at low processing temperatures using roll to roll printing on flexible substrates. Further, the basic materials properties can be tailored through organic synthetic routes. However, the issues related to its durability should be addressed before its commercialization. Hence, a conventional solar cell of the poly (3-hexylthiophene (P3HT :(6, 6-phenyl-C61butyric acid methyl ester (PC61BM blend on ITO substrates was fabricated, and investigated, which shows improved life time by using a combinational Ca/Al cathode, wherein the deposition of calcium layer is extended beyond the aluminum layer. The extended deposition of calcium layer beyond aluminum prevents the edge degradation by its oxidation and hence protecting the active pixel area of the device, resulting in the improvement of life time of device from ∼80 hours to ∼ 400 hrs.

  12. 46 CFR 34.10-10 - Fire station hydrants, hose and nozzles-T/ALL.

    Science.gov (United States)

    2010-10-01

    ... water, one of which shall be from a single 50-foot length of hose. In main machinery spaces all portions... must be located to afford protection from heavy seas. The hose must be stored in a location that is... Weather deck 4 10 or 12 Machinery space 2 4 (f) Each combination firehose nozzle previously approved under...

  13. 46 CFR 38.15-5 - Cargo hose-TB/ALL.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Cargo hose-TB/ALL. 38.15-5 Section 38.15-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS LIQUEFIED FLAMMABLE GASES Special Requirements § 38.15-5 Cargo hose—TB/ALL. (a) When the liquid and vapor line hoses used for loading and discharging...

  14. 46 CFR 76.10-10 - Fire station hydrants, hose and nozzles-T/ALL.

    Science.gov (United States)

    2010-10-01

    ... length of hose. For the purpose of this requirement, all watertight doors and all doors in main vertical... other than watertight doors and doors in main vertical zone bulkheads for the passage of the hose. In... drain valves so that the entire exposed parts of such piping may be shut off and drained in freezing...

  15. An extended life and performance test of a low-power arcjet

    Science.gov (United States)

    Curran, Francis M.; Haag, Thomas W.

    1988-01-01

    An automated, cyclic life test was performed to demonstrate the reliability and endurance of a low power dc cycle arcjet thruster. Over 1000 hr and 500 on-off cycles were accumulated which would represent the requirements for about 15 years of on-orbit lifetime. A hydrogen/nitrogen propellant mixture was used to simulate decomposed hydrazine propellant and the power level was nominally 1.2 kW after the burn-in period. The arcjet operated in a very repeatable fashion from cycle to cycle. The steady state voltage increased by approximately 6 V over the first 300 hr, and then by only 3 V through the remainder of the test. Thrust measurements taken before, during, and after the test verified that the thruster performed in a consistent fashion throughout the tests at a specific impulse of 450 to 460 sec. Post-test component evaluation revealed limited erosion on both the anode and cathode. Other thruster components, including graphite seals, appeared undamaged.

  16. Modernization and reconstruction of ageing Russian research reactors as the method to extend their operational life

    International Nuclear Information System (INIS)

    Khmelshchikov, V.V.; Tretjakov, I.T.; Portnov, A.A.; Vinogradov, A.V.

    2000-01-01

    The common situation in Russian atomic industry exhibits a tendency to steady aging of research reactor (RR) facilities and extremely limited financial means for constructing new equipment instead of old. Modernization and reconstruction of operating RR after their designed resources exhausted are the most optimum strategic prospects in nearest 10 years. With respect to modernization strategy the following positive factors are of great importance: (a) additional lands are not occupied for construction site; (b) the exploitation of reactor building and a considerable part of technological system equipment is in progress. Their operational life is longer than of in-reactor devices (subjected to irradiation and heating) as a rule, and lasts no less than 50-60 years; (c) experimental base, which may be improved to carry out new tasks, is retained; (d) skilled personnel is preserved, since it can be employed in resembling works during the reactor shutdown; (e) the main strategic object is to retain research and experimental base with minimum financial and temporal expenses. Two Russian RR IRT and IBR-2 can cite an example of general and concrete approach to the issues including safety enhancement and development of the reactor engineering with reconstruction and modernization of aging facilities. (author)

  17. Extending life of reversible heat exchangers; Prologando a vida util de trocadores de calor reversiveis

    Energy Technology Data Exchange (ETDEWEB)

    Fonseca, Ronaldo [White Martins de Ipatinga, MG (Brazil). Usina de Liquidos; Cabral, Antonio Tarciso S. [White Martins de Volta Redonda (Brazil). Usina de Liquidos

    2010-07-01

    Praxair is one of the three largest industrial gases companies worldwide, with operations in over 40 countries. In Brazil, Praxair is the owner of White Martins, the largest industrial gases company in South America, present in nine countries on the continent and throughout the Brazilian steel industry, operating and supplying products from plants for separation of air gases or other products and services for all steelmaking processes. In addition to technologies of production of atmospheric gases, White Martins includes the production of carbon dioxide, acetylene, hydrogen, specialty and health and care gases, mixtures for welding, gas seamless steel cylinders, storage and gases transportation, equipment for measurement and control of gas injection, following the strictest standards of safety and quality. This paper describe the improvements, availability and reliability gains achieved through implementation of operational control systems of RHX, equipment commonly found in air separation plants, which allowed better monitoring and increasing the useful life of these heat exchangers and to keep the purity of the products supplied for the manufacture of high quality steels. (author)

  18. Application of edible coating and acidic washing for extending the storage life of mushrooms (Agaricus bisporus).

    Science.gov (United States)

    Sedaghat, Naser; Zahedi, Younes

    2012-12-01

    Hydrocolloid-based materials have been extensively used to coat fruit and vegetables to prolong shelf-life. The effects of different concentrations of acidic washing (acetic, ascorbic, citric and malic acids) followed by coating with gum arabic (GA), carboxymethyl cellulose and emulsified gum arabic (EGA) were evaluated on the weight loss (WL), firmness and color of mushroom. The WL of the uncoated mushrooms was significantly (p acids showed minimum and maximum of WL, respectively. Loss in firmness of the EGA-coated mushrooms was by 21% (the minimum of loss), while loss value of the uncoated ones was by 39% (the maximum of loss). Firmness of mushrooms was not influenced by the acid type. Concentration of the acid significantly (p acid (1%), the mushrooms tissue was firmest. The L* value of the mushrooms coated with GA was higher than that of others. A significant (p acid. Overall, washing with 1% citric or malic acid followed by coating with EGA resulted in minimum decrease in WL and firmness of the mushrooms.

  19. Modified atmosphere packaging extending the storage life of 'douradão' peach

    Directory of Open Access Journals (Sweden)

    Ligia Regina Radomille de Santana

    2010-12-01

    Full Text Available 'Douradão' peach is a perishable product and when cold stored is subject to chilling injury. The objective of the experiment was to evaluate the effect of modified atmosphere packaging (MAP and cold storage on quality and storage life of these peaches. Fruits were packed in polypropylene (PP trays and placed inside low density polyethylene (LDPE bags (30, 50, 60, 75 μm thickness with active modified atmosphere (10 kPa CO2 + 1.5kPa O2, balance N2. The control was made with peaches held in nonwrapped PP trays. Fruits were kept at 1 ± 1 °C and 90 ± 5% relative humidity (RH for 28 days and CO2 and O2 within packages was monitored every two days. After 14, 21 and 28 days, samples were withdrawn from MAP and kept in air at 25 ± 1 °C and 90 ± 5% RH for ripening. On the day of removal from the cold storage and after 4 days, peaches were evaluated for weight loss, decay incidence, flesh firmness, woolliness incidence, soluble solids content (SSC, titratable acidity (TA and juice content. The results showed that MAP had influence on reducing weight loss and prevented postharvest decay. MAP of 1-2 kPa O2 and 3-6 kPa CO2 at 1 °C (from 50 and 60 μm LDPE films were effective for keeping good quality of 'Douradão' peaches during 28 days of storage, the ripe fruits showed reduced incidence of woolliness, adequate juiciness and flesh firmness. Packages of 30 and 75 μm LDPE films were ineffective for reducing woolliness during cold storage. MAP fruits showed lower SSC and no relevant effect on TA. Control fruits did not present marketable conditions after 14 days of cold storage.

  20. Recycling of photovoltaic end-of-life panels. International overview. Extended abstract

    International Nuclear Information System (INIS)

    Billard, Yannael; Bazin, F.; Lacroix, O.; Antonini, Gerard; Couffignal, Benedicte; Arnaud, Swellen; Binesti, Didier; Cimolino, Lauro; Fangeat, Erwann; Rance, Melanie; Soleille, Sebastien; Veronneau, Cyrille

    2012-10-01

    Since the early 2000's, the general awareness surrounding the importance of recycling by the users and producers of photovoltaic modules has contributed to the emergence of the end-of-life photovoltaic modules recycling activity. This awareness can be attributed to the growing concern on natural resource conservation; the natural shortage in some strategic metals used in photovoltaic; the reinforcement of regulatory framework on waste management in some countries; and the answer given to raising questions regarding the renewability of photovoltaic. In fact, the last ten years have been marked by significant research efforts, which have finally lifted the main technological barriers associated with the recycling of photovoltaic modules. Economically, the activity of recycling photovoltaic modules is not yet viable today, and is instead based on sources of compensation from the client, producer or organizations in charge of the modules collection, on top of the sale of recycled materials. Technology developers are now cautious of investment because the waste stream is still too weak and poorly controlled, the photovoltaic market is unstable, and high competitiveness is indicative of a recycling overcapacity, which could be increasingly significant by 2020. Following the definition of the study bases, the regulatory framework active in specific regions of the world is described, and an objective overview of the developing recycling sector is provided by analyzing all recycling processes, its organizational segmentation and the internal structure of relevant actors. The synthesis of this data provides a realistic guideline on the maturity of the industry and key strategies for the development of activities within this sector. Indeed, the success of this activity will rest partly on the ability of recycling actors to adapt their business model and administrative system to local regulatory framework, and adapt the size of their installation to the transitory volume

  1. L70 life prediction for solid state lighting using Kalman Filter and Extended Kalman Filter based models

    Energy Technology Data Exchange (ETDEWEB)

    Lall, Pradeep; Wei, Junchao; Davis, Lynn

    2013-08-08

    Solid-state lighting (SSL) luminaires containing light emitting diodes (LEDs) have the potential of seeing excessive temperatures when being transported across country or being stored in non-climate controlled warehouses. They are also being used in outdoor applications in desert environments that see little or no humidity but will experience extremely high temperatures during the day. This makes it important to increase our understanding of what effects high temperature exposure for a prolonged period of time will have on the usability and survivability of these devices. Traditional light sources “burn out” at end-of-life. For an incandescent bulb, the lamp life is defined by B50 life. However, the LEDs have no filament to “burn”. The LEDs continually degrade and the light output decreases eventually below useful levels causing failure. Presently, the TM-21 test standard is used to predict the L70 life of LEDs from LM-80 test data. Several failure mechanisms may be active in a LED at a single time causing lumen depreciation. The underlying TM-21 Model may not capture the failure physics in presence of multiple failure mechanisms. Correlation of lumen maintenance with underlying physics of degradation at system-level is needed. In this paper, Kalman Filter (KF) and Extended Kalman Filters (EKF) have been used to develop a 70-percent Lumen Maintenance Life Prediction Model for LEDs used in SSL luminaires. Ten-thousand hour LM-80 test data for various LEDs have been used for model development. System state at each future time has been computed based on the state space at preceding time step, system dynamics matrix, control vector, control matrix, measurement matrix, measured vector, process noise and measurement noise. The future state of the lumen depreciation has been estimated based on a second order Kalman Filter model and a Bayesian Framework. The measured state variable has been related to the underlying damage using physics-based models. Life

  2. Inducible knockdown of pregnancy-associated plasma protein-A gene expression in adult female mice extends life span.

    Science.gov (United States)

    Bale, Laurie K; West, Sally A; Conover, Cheryl A

    2017-08-01

    Pregnancy-associated plasma protein-A (PAPP-A) knockout (KO) mice, generated through homologous recombination in embryonic stem cells, have a significantly increased lifespan compared to wild-type littermates. However, it is unknown whether this longevity advantage would pertain to PAPP-A gene deletion in adult animals. In the present study, we used tamoxifen (Tam)-inducible Cre recombinase-mediated excision of the floxed PAPP-A (fPAPP-A) gene in mice at 5 months of age. fPAPP-A mice, which were either positive (pos) or negative (neg) for Tam-Cre, received Tam treatment with quarterly boosters. Only female mice could be used with this experimental design. fPAPP-A/neg and fPAPP-A/pos mice had similar weights at the start of the experiment and showed equivalent weight gain. We found that fPAPP-A/pos mice had a significant extension of life span (P = 0.005). The median life span was increased by 21% for fPAPP-A/pos compared to fPAPP-A/neg mice. Analysis of mortality in life span quartiles indicated that the proportion of deaths of fPAPP-A/pos mice were lower than fPAPP-A/neg mice at young adult ages (P = 0.002 for 601-800 days) and higher than fPAPP-A/neg mice at older ages (P = 0.004 for >1000 days). Thus, survival curves and age-specific mortality indicate that female mice with knockdown of PAPP-A gene expression as adults have an extended healthy life span. © 2017 The Authors. Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd.

  3. Metal-based superoxide dismutase and catalase mimics reduce oxidative stress biomarkers and extend life span of Saccharomyces cerevisiae.

    Science.gov (United States)

    Ribeiro, Thales de P; Fonseca, Fernanda L; de Carvalho, Mariana D C; Godinho, Rodrigo M da C; de Almeida, Fernando Pereira; Saint'Pierre, Tatiana D; Rey, Nicolás A; Fernandes, Christiane; Horn, Adolfo; Pereira, Marcos D

    2017-01-15

    Aging is a natural process characterized by several biological changes. In this context, oxidative stress appears as a key factor that leads cells and organisms to severe dysfunctions and diseases. To cope with reactive oxygen species and oxidative-related damage, there has been increased use of superoxide dismutase (SOD)/catalase (CAT) biomimetic compounds. Recently, we have shown that three metal-based compounds {[Fe(HPClNOL)Cl 2 ]NO 3 , [Cu(HPClNOL)(CH 3 CN)](ClO 4 ) 2 and Mn(HPClNOL)(Cl) 2 }, harboring in vitro SOD and/or CAT activities, were critical for protection of yeast cells against oxidative stress. In this work, treating Saccharomyces cerevisiae with these SOD/CAT mimics (25.0 µM/1 h), we highlight the pivotal role of these compounds to extend the life span of yeast during chronological aging. Evaluating lipid and protein oxidation of aged cells, it becomes evident that these mimics extend the life expectancy of yeast mainly due to the reduction in oxidative stress biomarkers. In addition, the treatment of yeast cells with these mimics regulated the amounts of lipid droplet occurrence, consistent with the requirement and protection of lipids for cell integrity during aging. Concerning SOD/CAT mimics uptake, using inductively coupled plasma mass spectrometry, we add new evidence that these complexes, besides being bioabsorbed by S. cerevisiae cells, can also affect metal homeostasis. Finally, our work presents a new application for these SOD/CAT mimics, which demonstrate a great potential to be employed as antiaging agents. Taken together, these promising results prompt future studies concerning the relevance of administration of these molecules against the emerging aging-related diseases such as Parkinson's, Alzheimer's and Huntington's. © 2017 The Author(s); published by Portland Press Limited on behalf of the Biochemical Society.

  4. Selected life-extending interventions reduce arterial CXCL10 and macrophage colony-stimulating factor in aged mouse arteries.

    Science.gov (United States)

    Trott, Daniel W; Lesniewski, Lisa A; Donato, Anthony J

    2017-08-01

    Cardiovascular disease (CVD) is the leading cause of death in the industrialized world. Aging is the most predictive risk factor for CVD and is associated with arterial inflammation which contributes to increased CVD risk. Although age-related arterial inflammation has been described in both humans and animals, only a limited number of inflammatory mediators, cytokines and chemokines have been identified. In this investigation we sought to determine whether lifespan extending interventions, including crowded litter early life nutrient deprivation (CL), traditional lifelong caloric restriction (CR) and lifelong Rapamycin treatment (Rap) would attenuate age-related arterial inflammation using multi analyte profiling. Aortas from Young (4-6months), Old (22months), Old CL, Old CR and Old Rap mice were homogenized and cytokine concentrations were assessed using Luminex Multi Analyte Profiling. Chemokines involved in immune cell recruitment, such as CCL2, CXCL9, CXCL10, GMCSF and MCSF, were increased in Old vs. Young (p<0.05). The age-related increase of CXCL10 was prevented by CR (p<0.05 vs. Old). MSCF concentrations were lower in aortas of Rap treated mice (p<0.05 vs. Old). Interleukins (IL), IL-1α, IL-1β and IL-10, were also greater in Old vs. Young mice (p<0.05). These data demonstrate selected lifespan extending interventions can prevent or limit age-related increases in selected aortic chemokines. Copyright © 2017. Published by Elsevier Ltd.

  5. Conceptual Framework To Extend Life Cycle Assessment Using Near-Field Human Exposure Modeling and High-Throughput Tools for Chemicals

    Science.gov (United States)

    Life Cycle Assessment (LCA) is a decision-making tool that accounts for multiple impacts across the life cycle of a product or service. This paper presents a conceptual framework to integrate human health impact assessment with risk screening approaches to extend LCA to include n...

  6. The impact of Hipparcos star-fixing extends to life's evolution

    Science.gov (United States)

    1997-05-01

    "ESA's Hipparcos brings the greatest step forward in star measurements since Tycho Brahe," Bonnet says. "When the Danish astronomer died in 1601, the German astronomer Johannes Kepler inherited his careful observations. Kepler used them to discover the laws of the motions of planets, and paved the way for Isaac Newton's gravitational theory. Now we have another multinational success story from European astronomy". "Hipparcos began as an imaginative French concept to chart the stars by satellite," Bonnet continues. "ESA adopted the idea and many astronomers in our member states collaborated in the mission. A hundred-fold improvement in the accuracy of star positions may already alter the size of the Universe and the ages of stars. So don't be surprised if the results from Hipparcos are as revolutionary as Tycho Brahe's, in their impact on our knowledge of the cosmos." The study of the Earth itself will benefit from the new star data. Wobbles of the Earth and variations in its rate of rotation can now be measured far more accurately. The ozone layer will be monitored by ESA's Envisat environmental mission, by looking for chemical alterations in the light from 1000 Hipparcos stars, when seen on lines of sight slanting through the atmosphere. Even the erratic evolution of life on Earth may make more sense, as Hipparcos picks out stars that passed close enough to cause trouble here. Reliable identifications of stars heading towards or away from our vicinity were impossible before Hipparcos. The satellite measured shifts in the directions of stars in the sky with such high precision that astronomers can now pick out those few stars that scarcely change their bearings. Such stars are probably moving almost directly towards or away from us. A US-European team, led by Robert Preston at the Jet Propulsion Laboratory in California, used Hipparcos to search for nearby stars with very small shifts in position. They were, or will be, passers-by. Gliese 710, an inconspicuous star

  7. Integrated Life Cycle Management: A Strategy for Plants to Extend Operating Lifetimes Safely with High Operational Reliability

    International Nuclear Information System (INIS)

    Esselman, Thomas; Bruck, Paul; Mengers, Charles

    2012-01-01

    Nuclear plant operators are studying the possibility of extending their existing generating facilities operating lifetime to 60 years and beyond. Many nuclear plants have been granted licenses to operate their facilities beyond the original 40 year term; however, in order to optimize the long term operating strategies, plant decision-makers need a consistent approach to support their options. This paper proposes a standard methodology to support effective decision-making for the long-term management of selected station assets. Methods detailed are intended to be used by nuclear plant site management, equipment reliability personnel, long term planners, capital asset planners, license renewal staff, and others that intend to look at operation between the current time and the end of operation. This methodology, named Integrated Life Cycle Management (ILCM), will provide a technical basis to assist decision makers regarding the timing of large capital investments required to get to the end of operation safely and with high plant reliability. ILCM seeks to identify end of life cycle failure probabilities for individual plant large capital assets and attendant costs associated with their refurbishment or replacement. It will provide a standard basis for evaluation of replacement and refurbishment options for these components. ILCM will also develop methods to integrate the individual assets over the entire plant thus assisting nuclear plant decision-makers in their facility long term operating strategies. (author)

  8. Bmi-1 extends the life span of normal human oral keratinocytes by inhibiting the TGF-{beta} signaling

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Reuben H., E-mail: rkim@dentistry.ucla.edu [UCLA School of Dentistry, Los Angeles, CA 90095 (United States); UCLA Dental Research Institute, Los Angeles, CA 90095 (United States); UCLA Jonsson Comprehensive Cancer Center, Los Angeles, CA 90095 (United States); Lieberman, Mark B.; Lee, Rachel [UCLA School of Dentistry, Los Angeles, CA 90095 (United States); Shin, Ki-Hyuk [UCLA School of Dentistry, Los Angeles, CA 90095 (United States); UCLA Dental Research Institute, Los Angeles, CA 90095 (United States); UCLA Jonsson Comprehensive Cancer Center, Los Angeles, CA 90095 (United States); Mehrazarin, Shebli; Oh, Ju-Eun [UCLA School of Dentistry, Los Angeles, CA 90095 (United States); Park, No-Hee [UCLA School of Dentistry, Los Angeles, CA 90095 (United States); UCLA Dental Research Institute, Los Angeles, CA 90095 (United States); UCLA Jonsson Comprehensive Cancer Center, Los Angeles, CA 90095 (United States); David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 (United States); Kang, Mo K., E-mail: mkang@dentistry.ucla.edu [UCLA School of Dentistry, Los Angeles, CA 90095 (United States); UCLA Dental Research Institute, Los Angeles, CA 90095 (United States); UCLA Jonsson Comprehensive Cancer Center, Los Angeles, CA 90095 (United States)

    2010-10-01

    We previously demonstrated that Bmi-1 extended the in vitro life span of normal human oral keratinocytes (NHOK). We now report that the prolonged life span of NHOK by Bmi-1 is, in part, due to inhibition of the TGF-{beta} signaling pathway. Serial subculture of NHOK resulted in replicative senescence and terminal differentiation and activation of TGF-{beta} signaling pathway. This was accompanied with enhanced intracellular and secreted TGF-{beta}1 levels, phosphorylation of Smad2/3, and increased expression of p15{sup INK4B} and p57{sup KIP2}. An ectopic expression of Bmi-1 in NHOK (HOK/Bmi-1) decreased the level of intracellular and secreted TGF-{beta}1 induced dephosphorylation of Smad2/3, and diminished the level of p15{sup INK4B} and p57{sup KIP2}. Moreover, Bmi-1 expression led to the inhibition of TGF-{beta}-responsive promoter activity in a dose-specific manner. Knockdown of Bmi-1 in rapidly proliferating HOK/Bmi-1 and cancer cells increased the level of phosphorylated Smad2/3, p15{sup INK4B}, and p57{sup KIP2}. In addition, an exposure of senescent NHOK to TGF-{beta} receptor I kinase inhibitor or anti-TGF-{beta} antibody resulted in enhanced replicative potential of cells. Taken together, these data suggest that Bmi-1 suppresses senescence of cells by inhibiting the TGF-{beta} signaling pathway in NHOK.

  9. Red fresh vegetables smoothies with extended shelf life as an innovative source of health-promoting compounds.

    Science.gov (United States)

    Castillejo, Noelia; Martínez-Hernández, Ginés Benito; Gómez, Perla A; Artés, Francisco; Artés-Hernández, Francisco

    2016-03-01

    Two fresh red vegetables smoothies based on tomato, carrots, pepper and broccoli and rich in health-promoting compounds were developed. The smoothies showed a viscoelastic behaviour. According to sensory analyses, a shelf life of 28 days at 5 °C for fresh blended smoothies was established while thermally-treated ones (3 min, 80 °C) reached up to 40 days at 20 °C and 58 days at 5 °C. For those mild heat treated smoothies, total vitamin C degradation was 2-fold reduced during storage at 5 °C compared to samples stored at 20 °C while the initial total carotenoids, lycopene and total chlorophylls contents were not greatly affected. A 250-g portion of such smoothies covers in a great extend the established recommended daily nutrient intakes for dietary fibre, minerals and vitamin C of different population groups. As main conclusion, a mild thermal treatment and low temperature storage greatly increased the shelf life of red fresh vegetables smoothies and reduced total vitamin C degradation.

  10. FIRE HOSE INSTABILITY DRIVEN BY ALPHA PARTICLE TEMPERATURE ANISOTROPY

    Energy Technology Data Exchange (ETDEWEB)

    Matteini, L.; Schwartz, S. J. [Department of Physics, Imperial College London, London SW7 2AZ (United Kingdom); Hellinger, P. [Astronomical Institute, CAS, Prague (Czech Republic); Landi, S. [Dipartimento di Fisica e Astronomia, Università di Firenze, Firenze (Italy)

    2015-10-10

    We investigate properties of a solar wind-like plasma, including a secondary alpha particle population exhibiting a parallel temperature anisotropy with respect to the background magnetic field, using linear and quasi-linear predictions and by means of one-dimensional hybrid simulations. We show that anisotropic alpha particles can drive a parallel fire hose instability analogous to that generated by protons, but that, remarkably, can also be triggered when the parallel plasma beta of alpha particles is below unity. The wave activity generated by the alpha anisotropy affects the evolution of the more abundant protons, leading to their anisotropic heating. When both ion species have sufficient parallel anisotropies, both of them can drive the instability, and we observe the generation of two distinct peaks in the spectra of the fluctuations, with longer wavelengths associated to alphas and shorter ones to protons. If a non-zero relative drift is present, the unstable modes propagate preferentially in the direction of the drift associated with the unstable species. The generated waves scatter particles and reduce their temperature anisotropy to a marginally stable state, and, moreover, they significantly reduce the relative drift between the two ion populations. The coexistence of modes excited by both species leads to saturation of the plasma in distinct regions of the beta/anisotropy parameter space for protons and alpha particles, in good agreement with in situ solar wind observations. Our results confirm that fire hose instabilities are likely at work in the solar wind and limit the anisotropy of different ion species in the plasma.

  11. STS-32 crewmembers use water hose during exercises at JSC fire training pit

    Science.gov (United States)

    1989-01-01

    STS-32 Commander Daniel C. Brandenstein (left) and Pilot James D. Wetherbee handle water hose during fire training exercises conducted at JSC Fire Training Pit across from the Gilruth Center Bldg 207.

  12. Extending the Life Time of a Nuclear Power Plant: Impact on Nuclear Liabilities in the Czech Republic

    Directory of Open Access Journals (Sweden)

    L. Havlíček

    2007-01-01

    Full Text Available Nuclear power plant (NPP operators have several basic long-term liabilities. Such liabilities include storage, treatment and disposal of radioactive waste generated at the operators’ NPP, storage and management of nuclear fuel irradiated in the reactor of the operator’s NPP (“spent fuel”, disposal of the spent fuel (SF or residues resulting from spent fuel reprocessing. Last but not least, the operator is liable for decommissioning its nuclear facilities. If the operator considers extending the life time of its NPP or if the construction of a new NPP is being evaluated by an investor, an integral part of the economic evaluation must be a comprehensive assessment of future incremental costs related to the above-mentioned long-term liabilities. An economic evaluation performed by standard methods (usually NPV, alternatively real options leads to a decision either to proceed with the project or to shelve it. If the investor decides to go ahead with the project there can be an immediate impact on nuclear liabilities. The impact is not the same for all operator liabilities. Depending on the valid legislation and the nature of the liability, in some cases the extent of the liability must be immediately recalculated when a decision is made to proceed with the project, and the annual accrual of accumulated reserves / funds must be adjusted. In other cases, the change in liability is linked to the generation of additional radioactive waste or spent fuel. In the Czech Republic, responsibility for each of the nuclear liabilities is defined, as is the form in which the financial means are to be accumulated. This paper deals with the impact of NPP life time extension (alternatively NPP power up-rate or construction of a new NPP on individual nuclear liabilities in the conditions of the Czech Republic. 

  13. Oblique proton fire hose instability in the expanding solar wind: Hybrid simulations

    Czech Academy of Sciences Publication Activity Database

    Hellinger, Petr; Trávníček, Pavel M.

    2008-01-01

    Roč. 113, A10 (2008), A10109/1-A10109/9 ISSN 0148-0227 R&D Projects: GA AV ČR IAA300420702; GA AV ČR IAA300420602 Institutional research plan: CEZ:AV0Z30420517; CEZ:AV0Z10030501 Keywords : kinetic instability * fire hose * solar wind * fire hose instabilities * linear analysis * nonlinear evolution * solar wind Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 3.147, year: 2008

  14. Gamma radiation applied to extend the shelf-life of lamb meat vacuum packed and stored under refrigeration

    International Nuclear Information System (INIS)

    Fregonesi, Raul Pereira

    2013-01-01

    days for pH and color b * (yellow), which declined and increased, respectively, over this period. In the sensory acceptance test, the samples did not differ (p> 0,05) in any of the evaluated attributes. Thus, it was concluded that gamma irradiation in the lamb loins was effective in decreasing the proliferation of microorganisms without damaging its physical and chemical characteristics. At the end of the experiment, it was possible to say that the 3.0 kGy dose was indicated because could extend the shelf life of 14 to 56 days of loin of lamb irradiated and stored at 1 °C . (author)

  15. Biogenic amine formation in turkey meat under modified atmosphere packaging with extended shelf life: Index of freshness.

    Science.gov (United States)

    Fraqueza, M J; Alfaia, C M; Barreto, A S

    2012-06-01

    The aim of this study was to evaluate the effect of modified atmosphere packaging (MAP) on biogenic amine production in turkey meat according to its shelf life period, determining an index of freshness. Sliced meat samples of different meat quality categories (according to color and pH₂₄) were individually packaged under aerobiosis (aerobic package) and in 6 different modified atmospheres containing different gas mixtures: MAP1, 50% N₂/50% CO₂; MAP2, 0.5% CO/50% CO₂/49.5% N₂; MAP3, 50% Ar/50% N₂; MAP4, 0.5% CO/80% CO₂/19.5% N₂; MAP5, 100% N₂; and MAP6, 50% Ar/50% CO₂. All samples were stored at 0 ± 1°C in the dark for between 12 and 25 d. Meat samples packaged in aerobic packaging were analyzed for their microbial and physicochemical characteristics on d 0, 5, and 12 of storage, and then extended to 19 and 25 d when samples were under MAP. The production of biogenic amines analyzed in turkey meat increased over time. The values of putrescine, cadaverine, and tyramine increased significantly (P < 0.05) during storage time in samples packaged under aerobiosis, MAP3, and MAP5. Histamine was not detected in turkey meat packaged under study conditions, or when present, the levels were below the limit of quantification (1.03 mg/kg). Tyramine in turkey meat under MAP was not the best amine indicator of meat deterioration, with cadaverine being suggested instead, or the sum of the amines putrescine, cadaverine, and tyramine, to characterize and quantify meat freshness. After 25 d of storage, the meat packaged under MAP with a mixture containing a higher concentration of CO₂ and with CO was the one with a lower index value (11.36 mg/kg), although not significantly different from the indices provided by the meat packaged with MAP1, 2, and 6.

  16. Life Cycle Thinking and Integrated Product Deliveries in renovation projects: Extending the concept of Integrated Product Deliveries with Product Service Systems

    DEFF Research Database (Denmark)

    Schipull Kauschen, Jan

    2012-01-01

    extension to the concept of IPDs discussed. Due to extended product responsibility, the concept of PSSs will offer new possibilities of planning and pre-defining life cycles of IPDs more precisely than for regular building components. Reducing or eliminating point-of-sales will induce producers to optimize...

  17. Identification, Characterization and Antibiotic Resistance of Bacterial Isolates Obtained from Waterpipe Device Hoses

    Directory of Open Access Journals (Sweden)

    Majed M. Masadeh

    2015-05-01

    Full Text Available The general lack of knowledge about the health effects of waterpipe smoking is among the reasons for its global spread. In this study, bacterial contamination of waterpipe hoses was investigated. Twenty hoses were collected from waterpipe cafés and screened for bacterial pathogens using standard culture and isolation techniques. Additionally, resistance of isolated bacteria to common antibiotics was determined by identifying the minimum inhibitory concentration (MIC of each isolate. Forty eight bacterial isolates were detected. Isolates included both Gram-positive and Gram-negative pathogens from species that included Micrococcus (12, Corynebacterium (13 and Bacillus (9. In addition, some of the detected pathogens were found to be resistant to aztreonam (79%, cefixime (79%, norfloxacin, amoxicillin (47%, clarithromycin (46% and enrofloxacin (38%. In conclusion, the hose of the waterpipe device is a good environment for the growth of bacterial pathogens, which can then be transmitted to users.

  18. Identification, characterization and antibiotic resistance of bacterial isolates obtained from waterpipe device hoses.

    Science.gov (United States)

    Masadeh, Majed M; Hussein, Emad I; Alzoubi, Karem H; Khabour, Omar; Shakhatreh, Muhamad Ali K; Gharaibeh, Mahmoud

    2015-05-13

    The general lack of knowledge about the health effects of waterpipe smoking is among the reasons for its global spread. In this study, bacterial contamination of waterpipe hoses was investigated. Twenty hoses were collected from waterpipe cafés and screened for bacterial pathogens using standard culture and isolation techniques. Additionally, resistance of isolated bacteria to common antibiotics was determined by identifying the minimum inhibitory concentration (MIC) of each isolate. Forty eight bacterial isolates were detected. Isolates included both Gram-positive and Gram-negative pathogens from species that included Micrococcus (12), Corynebacterium (13) and Bacillus (9). In addition, some of the detected pathogens were found to be resistant to aztreonam (79%), cefixime (79%), norfloxacin, amoxicillin (47%), clarithromycin (46%) and enrofloxacin (38%). In conclusion, the hose of the waterpipe device is a good environment for the growth of bacterial pathogens, which can then be transmitted to users.

  19. Internal Thermal Control System Hose Heat Transfer Fluid Thermal Expansion Evaluation Test Report

    Science.gov (United States)

    Wieland, P. O.; Hawk, H. D.

    2001-01-01

    During assembly of the International Space Station, the Internal Thermal Control Systems in adjacent modules are connected by jumper hoses referred to as integrated hose assemblies (IHAs). A test of an IHA has been performed at the Marshall Space Flight Center to determine whether the pressure in an IHA filled with heat transfer fluid would exceed the maximum design pressure when subjected to elevated temperatures (up to 60 C (140 F)) that may be experienced during storage or transportation. The results of the test show that the pressure in the IHA remains below 227 kPa (33 psia) (well below the 689 kPa (100 psia) maximum design pressure) even at a temperature of 71 C (160 F), with no indication of leakage or damage to the hose. Therefore, based on the results of this test, the IHA can safely be filled with coolant prior to launch. The test and results are documented in this Technical Memorandum.

  20. The role of spices and lactic acid bacteria as antimicrobial agent to extend the shelf life of metata ayib (traditional Ethiopian spiced fermented cottage cheese)

    OpenAIRE

    Geremew, Tsehayneh; Kebede, Ameha; Andualem, Berhanu

    2015-01-01

    Spices and lactic acid bacteria have natural antimicrobial substances and organic compounds having antagonistic activity against microorganisms. The objective of this study was to investigate the role of spices and lactic acid bacteria as antimicrobial agent to extend the shelf life of metata ayib. Antimicrobial activities of spices and lactic acid bacteria (LAB) filtrates were determined by agar well diffusion method against E. coli, S. aureus, S. flexneri and S. peumoniae. Aantimicrobial ac...

  1. Different Reactive Oxygen Species Scavenging Properties of Flavonoids Determine Their Abilities to Extend the Shelf Life of Tomato.

    Science.gov (United States)

    Zhang, Yang; De Stefano, Rosalba; Robine, Marie; Butelli, Eugenio; Bulling, Katharina; Hill, Lionel; Rejzek, Martin; Martin, Cathie; Schoonbeek, Henk-jan

    2015-11-01

    The shelf life of tomato (Solanum lycopersicum) fruit is determined by the processes of overripening and susceptibility to pathogens. Postharvest shelf life is one of the most important traits for commercially grown tomatoes. We compared the shelf life of tomato fruit that accumulate different flavonoids and found that delayed overripening is associated with increased total antioxidant capacity caused by the accumulation of flavonoids in the fruit. However, reduced susceptibility to Botrytis cinerea, a major postharvest fungal pathogen of tomato, is conferred by specific flavonoids only. We demonstrate an association between flavonoid structure, selective scavenging ability for different free radicals, and reduced susceptibility to B. cinerea. Our study provides mechanistic insight into how flavonoids influence the shelf life, information that could be used to improve the shelf life of tomato and, potentially, other soft fruit. © 2015 American Society of Plant Biologists. All Rights Reserved.

  2. Different Reactive Oxygen Species Scavenging Properties of Flavonoids Determine Their Abilities to Extend the Shelf Life of Tomato1[OPEN

    Science.gov (United States)

    Zhang, Yang; De Stefano, Rosalba; Robine, Marie; Butelli, Eugenio; Bulling, Katharina; Hill, Lionel; Rejzek, Martin; Martin, Cathie; Schoonbeek, Henk-jan

    2015-01-01

    The shelf life of tomato (Solanum lycopersicum) fruit is determined by the processes of overripening and susceptibility to pathogens. Postharvest shelf life is one of the most important traits for commercially grown tomatoes. We compared the shelf life of tomato fruit that accumulate different flavonoids and found that delayed overripening is associated with increased total antioxidant capacity caused by the accumulation of flavonoids in the fruit. However, reduced susceptibility to Botrytis cinerea, a major postharvest fungal pathogen of tomato, is conferred by specific flavonoids only. We demonstrate an association between flavonoid structure, selective scavenging ability for different free radicals, and reduced susceptibility to B. cinerea. Our study provides mechanistic insight into how flavonoids influence the shelf life, information that could be used to improve the shelf life of tomato and, potentially, other soft fruit. PMID:26082399

  3. Extending Experiences

    DEFF Research Database (Denmark)

    A computer game's player is experiencing not only the game as a designer-made artefact, but also a multitude of social and cultural practices and contexts of both computer game play and everyday life. As a truly multidisciplinary anthology, Extending Experiences sheds new light on the mesh...... of possibilities and influences the player engages with. Part one, Experiential Structures of Play, considers some of the key concepts commonly used to address the experience of a computer game player. The second part, Bordering Play, discusses conceptual and practical overlaps of games and everyday life...... and the impacts of setting up, crossing and breaking the boundaries of game and non-game. Part three, Interfaces of Play, looks at games as technological and historical artefacts and commodities. The fourth part, Beyond Design, introduces new models for the practical and theoretical dimensions of game design....

  4. Life Cycle Thinking and Integrated Product Deliveries in renovation projects: Extending the concept of Integrated Product Deliveries with Product Service Systems

    DEFF Research Database (Denmark)

    Schipull Kauschen, Jan

    2012-01-01

    on renovation projects from Denmark, using different forms of IPDs for façade renovation and discusses the different stakeholder’s perspectives on life cycle thinking and their interests and values regarding sustainable building. Furthermore is the concept of Product Service Systems (PSS) as a valuable...... IPDs with regard to longevity and adaptability. CONCLUSION The new type of service-focused IPD and the related life-cycle responsibility (development, building phase, maintenance and dismantling/adaption/recycling) creates incentive to integrate life cycle thinking into the development process of IPDs......, resulting in more sustainable building solutions with a greater extend of positive environmental, economical and social impacts. The research presented will also show the importance of adaption and configuration of these complex building components by architects and planners, as they will have a great...

  5. Climatic impacts of fresh water hosing under Last Glacial Maximum conditions: a multi-model study

    NARCIS (Netherlands)

    Kageyama, M.; Merkel, U.; Otto-Bliesner, B.; Prange, M.; Abe-Ouchi, A.; Lohmann, G.; Ohgaito, R.; Roche, D.M.V.A.P.; Singarayer, J

    2013-01-01

    Fresh water hosing simulations, in which a fresh water flux is imposed in the North Atlantic to force fluctuations of the Atlantic Meridional Overturning Circulation, have been routinely performed, first to study the climatic signature of different states of this circulation, then, under present or

  6. 49 CFR 178.345-9 - Pumps, piping, hoses and connections.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Pumps, piping, hoses and connections. 178.345-9 Section 178.345-9 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS... FOR PACKAGINGS Specifications for Containers for Motor Vehicle Transportation § 178.345-9 Pumps...

  7. 46 CFR 28.820 - Fire pumps, fire mains, fire hydrants, and fire hoses.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Fire pumps, fire mains, fire hydrants, and fire hoses... REQUIREMENTS FOR COMMERCIAL FISHING INDUSTRY VESSELS Aleutian Trade Act Vessels § 28.820 Fire pumps, fire mains... pump connected to a fixed piping system. This pump must be capable of delivering an effective stream of...

  8. 46 CFR 28.315 - Fire pumps, fire mains, fire hydrants, and fire hoses.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Fire pumps, fire mains, fire hydrants, and fire hoses... After September 15, 1991, and That Operate With More Than 16 Individuals on Board § 28.315 Fire pumps... be equipped with a self-priming, power driven fire pump connected to a fixed piping system. (1) A...

  9. Linear and non-linear calculations of the hose instability in the ion-focused regime

    International Nuclear Information System (INIS)

    Buchanan, H.L.

    1982-01-01

    A simple model is adopted to study the hose instability of an intense relativistic electron beam in a partially neutralized, low density ion channel (ion focused regime). Equations of motion for the beam and the channel are derived and linearized to obtain an approximate dispersion relation. The non-linear equations of motion are then solved numerically and the results compared to linearized data

  10. On MHD waves, fire-hose and mirror instabilities in anisotropic plasmas

    Directory of Open Access Journals (Sweden)

    L.-N. Hau

    2007-09-01

    Full Text Available Temperature or pressure anisotropies are characteristic of space plasmas, standard magnetohydrodynamic (MHD model for describing large-scale plasma phenomena however usually assumes isotropic pressure. In this paper we examine the characteristics of MHD waves, fire-hose and mirror instabilities in anisotropic homogeneous magnetized plasmas. The model equations are a set of gyrotropic MHD equations closed by the generalized Chew-Goldberger-Low (CGL laws with two polytropic exponents representing various thermodynamic conditions. Both ions and electrons are allowed to have separate plasma beta, pressure anisotropy and energy equations. The properties of linear MHD waves and instability criteria are examined and numerical examples for the nonlinear evolutions of slow waves, fire-hose and mirror instabilities are shown. One significant result is that slow waves may develop not only mirror instability but also a new type of compressible fire-hose instability. Their corresponding nonlinear structures thus may exhibit anticorrelated density and magnetic field perturbations, a property used for identifying slow and mirror mode structures in the space plasma environment. The conditions for nonlinear saturation of both fire-hose and mirror instabilities are examined.

  11. Extending the shelf life of edible flowers with controlled release of 1-methylcyclopropene and modified atmosphere packaging

    Science.gov (United States)

    Edible flowers have great sensory appeal, but their extremely short shelf life limits their commercial usage. Postharvest 1-methylcyclopropene (1-MCP) treatment is used to counter ethylene activity and delay senescence in fresh produce; however its potential application in edible flowers has not bee...

  12. Testing of selected metallic reinforcing bars for extending the service life of future concrete bridges : testing in outdoor concrete blocks.

    Science.gov (United States)

    2002-01-01

    To meet the challenge of a design life of 100 years for major concrete bridges, economical and corrosion-resistant reinforcing bars will be needed. The preliminary results for stainless steel-clad bars in a recent investigation funded by the Federal ...

  13. Is "end of life" a special case? Connecting Q with survey methods to measure societal support for views on the value of life-extending treatments.

    Science.gov (United States)

    Mason, Helen; Collins, Marissa; McHugh, Neil; Godwin, Jon; Van Exel, Job; Donaldson, Cam; Baker, Rachel

    2018-01-19

    Preference elicitation studies reporting societal views on the relative value of end-of-life treatments have produced equivocal results. This paper presents an alternative method, combining Q methodology and survey techniques (Q2S) to determine the distribution of 3 viewpoints on the relative value of end-of-life treatments identified in a previous, published, phase of this work. These were Viewpoint 1, "A population perspective: value for money, no special cases"; Viewpoint 2, "Life is precious: valuing life-extension and patient choice"; and Viewpoint 3, "Valuing wider benefits and opportunity cost: the quality of life and death." A Q2S survey of 4,902 respondents across the United Kingdom measured agreement with these viewpoints; 37% most agreed with Viewpoint 1, 49% with Viewpoint 2, and 9% with Viewpoint 3. Regression analysis showed associations of viewpoints with gender, level of education, religion, voting preferences, and satisfaction with the NHS. The Q2S approach provides a promising means to investigate how in-depth views and opinions are represented in the wider population. As demonstrated in this study, there is often more than 1 viewpoint on a topic and methods that seek to estimate that averages may not provide the best guidance for societal decision-making. © 2018 The Authors. Health Economics Published by John Wiley & Sons Ltd.

  14. Effectiveness of two-sided UV-C treatments in inhibiting natural microflora and extending the shelf-life of minimally processed 'Red Oak Leaf' lettuce.

    Science.gov (United States)

    Allende, Ana; McEvoy, James L; Luo, Yaguang; Artes, Francisco; Wang, Chien Y

    2006-05-01

    The use of UV-C radiation treatments to inhibit the microbial growth and extend the shelf-life of minimally processed 'Red Oak Leaf' lettuce was investigated. Initially, UV-C resistance of 20 bacterial strains from different genera often associated with fresh produce (Enterobacter, Erwinia, Escherichia, Leuconostoc, Pantoea, Pseudomonas, Rahnela, Salmonella, Serratia and Yersinia) were tested in vitro. Most of the bacterial strains were inhibited with the minimum dose (30 J m(-2)). Erwinia carotovora, Leuconostoc carnosum, Salmonella typhimurium, and Yersinia aldovae were the most resistant strains requiring a UV-C dose of 85 J m(-2) to completely inhibit growth. An in vivo study consisted of treating minimally processed 'Red Oak Leaf' lettuce (Lactuca sativa) with UV-C at three radiation doses (1.18, 2.37 and 7.11 kJ m(-2)) on each side of the leaves and storing the product under passive MAP conditions at 5 degrees C for up to 10 days. The gas composition inside packages varied significantly among the treatments, with CO2 concentrations positively and O2 concentrations negatively correlating with the radiation dose. All the radiation doses were effective in reducing the natural microflora of the product, although the highest doses showed the greatest microbial inhibitions. Taking into account the microbial limit set by Spanish legislation [Boletín Oficial del Estado (BOE), 2001. Normas de higiene para la elaboración, distribución y comercio de comidas preparadas, Madrid, Spain, Real Decreto 3484/2000, pp. 1435-1441], all UV-C treatments extended the shelf-life of the product. However, the 7.11 kJ m(-2) dose induced tissue softening and browning after 7 days of storage at 5 degrees C. Therefore, the use of two sided UV-C radiation, at the proper dose, is effective in reducing the natural microflora and extending the shelf-life of minimally processed 'Red Oak Leaf' lettuce.

  15. Extending the shelf-life of citrus fruits using irradiation and/or other treatments I. 'Balady' oranges

    International Nuclear Information System (INIS)

    Abd-Allah, M.A.; Khallaf, M.F.; Mahmoud, A.A.; Salem, M.H.

    1996-01-01

    Irradiation process (0, 1.50 and 2.50 kGy) gamma radiation with or without other treatments before irradiation, i.e. soaking in CaCl 2 solution or waxing were used in this study to investigate the effect of such treatments on the shelf-life of 'Balady' orange fruits at room temperature. Marketable properties (browning, decay and texture) in addition to the organoleptic evaluation of firmness, appearance, odour, colour and taste were detected. Results showed the preferability of waxing treatment before irradiation processes. On the other hand, statistical analysis of the organoleptic evaluation revealed that the shelf-life of untreated sample (control) was 20 days at room temperature, while samples exposed to the different suggested treatments were rejected after 30 days under the same conditions. (author)

  16. The Life Cycle Completed. Extended Version with New Chapters on the Ninth Stage of Development by Joan M. Erikson.

    Science.gov (United States)

    Erikson, Erik H.

    This expanded edition of a 1982 book by Erik Erikson summarizes his work on the stages of the human life cycle, including chapters on psychosexuality and the cycle of generations, major stages in psychosocial development, and ego and ethos. An additional chapter on the ninth stage sets forth his philosophy on old age--i.e. the 80s and 90s--and how…

  17. Extending life for people with a terminal illness: a moral right and an expensive death? Exploring societal perspectives.

    Science.gov (United States)

    McHugh, Neil; Baker, Rachel M; Mason, Helen; Williamson, Laura; van Exel, Job; Deogaonkar, Rohan; Collins, Marissa; Donaldson, Cam

    2015-03-07

    Many publicly-funded health systems apply cost-benefit frameworks in response to the moral dilemma of how best to allocate scarce healthcare resources. However, implementation of recommendations based on costs and benefit calculations and subsequent challenges have led to 'special cases' with certain types of health benefits considered more valuable than others. Recent debate and research has focused on the relative value of life extensions for people with terminal illnesses. This research investigates societal perspectives in relation to this issue, in the UK. Q methodology was used to elicit societal perspectives from a purposively selected sample of data-rich respondents. Participants ranked 49 statements of opinion (developed for this study), onto a grid, according to level of agreement. These 'Q sorts' were followed by brief interviews. Factor analysis was used to identify shared points of view (patterns of similarity between individuals' Q sorts). Analysis produced a three factor solution. These rich, shared accounts can be broadly summarised as: i) 'A population perspective - value for money, no special cases', ii) 'Life is precious - valuing life-extension and patient choice', iii) 'Valuing wider benefits and opportunity cost - the quality of life and death'. From the factor descriptions it is clear that the main philosophical positions that have long dominated debates on the just allocation of resources have a basis in public opinion. The existence of certain moral positions in the views of society does not ethically imply, and pragmatically cannot mean, that all are translated into policy. Our findings highlight normative tensions and the importance of critically engaging with these normative issues (in addition to the current focus on a procedural justice approach to health policy). Future research should focus on i) the extent to which these perspectives are supported in society, ii) how respondents' perspectives relate to specific resource allocation

  18. Extending the Life-Course Interdependence Model: Life Transitions and the Enduring Consequences of Early Self-Derogation for Young Adult Crime

    Science.gov (United States)

    Eitle, David; Taylor, John; Pih, Kay Kei-ho

    2010-01-01

    Few studies exploring the association between adolescent self-esteem and crime have considered whether the early adolescent self-esteem has any enduring consequences for young adult crime. Inspired by the life course and developmental criminology approaches, Arnett's notion of emerging adulthood, and Kaplan's self-derogation theory, this article…

  19. Evolution of umbilicals in Brazil: optimizing deepwater umbilical applications with thermoplastic hoses and steel tubes

    Energy Technology Data Exchange (ETDEWEB)

    Guerra Neto, Mauro Del [DuPont do Brasil S.A., Barueri, SP (Brazil)

    2008-07-01

    Subsea umbilicals in the past 25 years have evolved in parallel with other subsea oil and gas technologies, as the search for hydrocarbons needed to drive the global economy has led offshore exploration and development companies to seek reserves ever-farther from shore in water thousands of meters deep. Relegated to little more than afterthought status before the push into deep water, modern umbilicals have now become crucial components linking deep water producers to their subsea wells, controlling subsea production systems through hydraulic and electrical power and injecting production chemicals for corrosion-, scale-, and hydrate-inhibition at subsea well heads. Particularly in subsea developments involving several deep water wells, umbilicals today are integral to both the production-system design and the chosen operating strategy. Failure of an umbilical linking a subsea well head in deep water to a host production facility can inflict severe economic consequences upon an operator by impairing production operations or halting production altogether. The additional cost of repairing or replacing a failed umbilical can run into the millions of dollars. As offshore oil and gas production has moved into ever-deeper water, umbilical manufacturers have begun introducing new stronger materials to handle the inherently higher pressures and temperatures. Today, two types of construction are used for fluid conduits in umbilical systems deployed in deep water: thermoplastic hoses and steel tubes. Steel tubes are generally more expensive than thermoplastic hoses, relatively stiff and considered to have high tensile strength, while thermoplastic hoses are extremely flexible and exhibit lower tensile strength. This lower tensile strength of the hoses may be compensated by including steel wire armoring in the umbilical. This also provides the added benefits of additional mechanical protection compared with the equivalent unarmored steel-tubes umbilicals. When either

  20. Effect of Mentha pulegium extract and 8-hydroxy quinoline sulphate to extend the quality and vase life of rose (Rosa hybrid) cut flower.

    Science.gov (United States)

    Hashemabadi, Davood; Torkashvand, Ali Mohammadi; Kaviani, Behzad; Bagherzadeh, Maryam; Rezaalipour, Mohaddeseh; Zarchini, Mohammad

    2015-01-01

    Rose is an ornamental plant which contains one of the world's top cut flowers. Vase life of cut rose flower is short. Extracts of Mentha pulegium and 8-hydroxy quinoline sulphate (8-HQS) were used as two preservative solutions, aiming to extend the vase life of cut rose (Rosa hybrid L.) flowers. Rose flowers were treated with a vase solution containing the extract of M. pulegium, at concentrations of 0, 10, 20 and 30%, in combination with 8-HQS at concentrations of 0, 200, 400 and 600 mg l(-1). Longevity of cut roses flowers was determined on the basis of wilting and chlorophyll retention. Cut roses flowers were kept at room temperature (20 ± 2 degrees C) under normal day light and natural ventilation. The vase life of cut flowers studied was prolonged by all 8-HQS and extract treatments. The best concentration of 8-HQS and extractwere 400 mg l(-1) and 10%, respectively. Our results indicated that the flowers treated with the extract and 8-HQS had longer vase life, higher rate of solution uptake and lower SPAD value (total chlorophyll) compared to the control. Also, cut flowers treated with the extract and 8-HQS had least bacterial colonies. The greatest longevity of vase life by 11.20 and 10.25 days was related to 400 mg I(-1) 8-HQS and 10% of extract, respectively. These treatments improved cut vase life more than the control treatment. The maximum solution uptake (1.85 ml g(-1) f.wt.) and minimum SPAD value (2.19) were calculated in 30% extract along with 200 mg l(-1) 8-HQS, and 200 mg l(-1) 8-HQS, respectively. The lowest number of bacterial colonies (55.75) was obtained in treatment of 600 mg l(-1) 8-HQS. Flower quality of specimens treated with extract and 8-HQS was better than those of the control. The experiments were repeated three times with three replicates and a completely randomized design had been used. The present study concludes that it would be possible to use preservative solutions containing extract of M. pulegium L. and 8-HQS to extend vase

  1. A novel exendin-4 human serum albumin fusion protein, E2HSA, with an extended half-life and good glucoregulatory effect in healthy rhesus monkeys

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Ling; Wang, Lin; Meng, Zhiyun; Gan, Hui; Gu, Ruolan; Wu, Zhuona; Gao, Lei; Zhu, Xiaoxia; Sun, Wenzhong; Li, Jian; Zheng, Ying; Dou, Guifang, E-mail: douguifang@vip.163.com

    2014-03-07

    Highlights: • E2HSA has an extended half-life and good plasma stability. • E2HSA could improve glucose-dependent insulin secretion. • E2HSA has excellent glucoregulatory effects in vivo. • E2HSA could potentially be used as a new long-acting GLP-1 receptor agonist for type 2 diabetes management. - Abstract: Glucagon-like peptide-1 (GLP-1) has attracted considerable research interest in terms of the treatment of type 2 diabetes due to their multiple glucoregulatory functions. However, the short half-life, rapid inactivation by dipeptidyl peptidase-IV (DPP-IV) and excretion, limits the therapeutic potential of the native incretin hormone. Therefore, efforts are being made to develop the long-acting incretin mimetics via modifying its structure. Here we report a novel recombinant exendin-4 human serum albumin fusion protein E2HSA with HSA molecule extends their circulatory half-life in vivo while still retaining exendin-4 biological activity and therapeutic properties. In vitro comparisons of E2HSA and exendin-4 showed similar insulinotropic activity on rat pancreatic islets and GLP-1R-dependent biological activity on RIN-m5F cells, although E2HSA was less potent than exendin-4. E2HSA had a terminal elimation half-life of approximate 54 h in healthy rhesus monkeys. Furthermore, E2HSA could reduce postprandial glucose excursion and control fasting glucose level, dose-dependent suppress food intake. Improvement in glucose-dependent insulin secretion and control serum glucose excursions were observed during hyperglycemic clamp test (18 h) and oral glucose tolerance test (42 h) respectively. Thus the improved physiological characterization of E2HSA make it a new potent anti-diabetic drug for type 2 diabetes therapy.

  2. Effect of Ethanol and Essential Oils on Extending Vase-life of Carnation Cut Flower (Dianthus caryophyllus cv. �Yellow Candy�

    Directory of Open Access Journals (Sweden)

    Hassan BAYAT

    2011-11-01

    Full Text Available The aim of the present study was to evaluate the effects of ethanol and essential oils of three medicinal plants namely Thyme (Thymus vulgaris L., Summer savory (Satureja hortensis L. and Ajwain (Carum copticum L. on extending carnation (Dianthus caryophyllus vase-life. For this purpose three individual trials were conducted using a completely randomized block design with three replications. In the first trial, the effect of 4% ethanol (v/v as a continuous or pulse treatment was determined. The results showed that although both application methods increased vase-life and marketability of carnation, it was statistically non significant. In the second trial, the effects of selected essential oils at the concentration of 100, 150 and 200 ppm were investigated. All essential oils prolonged carnation vase-life. Summer savory essential oil (100 ppm showed the highest effect (increasing 4.4 days in comparison to the control. In the third trial, the interaction between ethanol and the essential oils was studied. Results showed there is no significant difference between application of essential oils alone and in combination with ethanol. The highest fresh weight was observed in cut flowers treated with Summer savory essential oil at 100 ppm after 6 days which was double compared to the control. According to the results of this research it is concluded that essential oils, (natural, safe and biodegradable compounds as novel alternative materials are suitable for prolongation of carnation vase-life.

  3. Spoilage of Microfiltered and Pasteurized Extended Shelf Life Milk Is Mainly Induced by Psychrotolerant Spore-Forming Bacteria that often Originate from Recontamination.

    Science.gov (United States)

    Doll, Etienne V; Scherer, Siegfried; Wenning, Mareike

    2017-01-01

    Premature spoilage and varying product quality due to microbial contamination still constitute major problems in the production of microfiltered and pasteurized extended shelf life (ESL) milk. Spoilage-associated bacteria may enter the product either as part of the raw milk microbiota or as recontaminants in the dairy plant. To identify spoilage-inducing bacteria and their routes of entry, we analyzed end products for their predominant microbiota as well as the prevalence and biodiversity of psychrotolerant spores in bulk tank milk. Process analyses were performed to determine the removal of psychrotolerant spores at each production step. To detect transmission and recontamination events, strain typing was conducted with isolates obtained from all process stages. Microbial counts in 287 ESL milk packages at the end of shelf life were highly diverse ranging from shelf life is influenced only to a minor extent by raw-milk-associated factors. In contrast, recontamination with spores, particularly from the B. cereus complex, seems to occur. To enhance milk quality throughout the entire shelf life, improved plant sanitation and disinfection that target the elimination of spores are necessary.

  4. Effect of nano-silver and boric acid on extending the vase life of cut rose (Rosa hybrida L.).

    Science.gov (United States)

    Hashemabadi, Davood; Liavali, Mahbanoo Hoseinzadeh; Kaviani, Behzad; Mousavi, Meysam; Keyghobadi, Saghi; Zahiri, Samaneh

    2014-09-01

    Silver nano-particles (2-5 nm diam.), as antimicrobial agent and boric acid, as ethylene production inhibitor are used for enhancing the quality and vase life of cut flowers. In the present study the effects of a preservative solution containing nano-silver and boric acid on some traits of cut rose (Rosa hybrida L. cv. Yellow Island) including vase life, ethylene production, dry weight percentage, chlorophyll content, flower opening index, beta-carotene of petals and the number of basal stem end bacteria were investigated. The results showed that the effect of nano-silver and boric acid as either solitary or in combination with each other were significant (p cut flower longevity (9.69 day) was obtained in pulse-treated flowers with 100 mg l(-1) boric acid. The least ethylene production (0.59 nl(-1) g(-1) h(-1)) was observed in cut rose treated with 100 mg l(-1) boric acid along with 5 mg l(-1) nano-silver. The lowest number of bacteria in the end of stem was calculated in cut flowers treated with the highest concentrations of boric acid (300 mg l(-1)) and nano-silver (20 mg l(-1)).

  5. Fab-dsFv: A bispecific antibody format with extended serum half-life through albumin binding

    Science.gov (United States)

    Davé, Emma; Adams, Ralph; Zaccheo, Oliver; Carrington, Bruce; Compson, Joanne E.; Dugdale, Sarah; Airey, Michael; Malcolm, Sarah; Hailu, Hanna; Wild, Gavin; Turner, Alison; Heads, James; Sarkar, Kaushik; Ventom, Andrew; Marshall, Diane; Jairaj, Mark; Kopotsha, Tim; Christodoulou, Louis; Zamacona, Miren; Lawson, Alastair D.; Heywood, Sam; Humphreys, David P.

    2016-01-01

    ABSTRACT An antibody format, termed Fab-dsFv, has been designed for clinical indications that require monovalent target binding in the absence of direct Fc receptor (FcR) binding while retaining substantial serum presence. The variable fragment (Fv) domain of a humanized albumin-binding antibody was fused to the C-termini of Fab constant domains, such that the VL and VH domains were individually connected to the Cκ and CH1 domains by peptide linkers, respectively. The anti-albumin Fv was selected for properties thought to be desirable to ensure a durable serum half-life mediated via FcRn. The Fv domain was further stabilized by an inter-domain disulfide bond. The bispecific format was shown to be thermodynamically and biophysically stable, and retained good affinity and efficacy to both antigens simultaneously. In in vivo studies, the serum half-life of Fab-dsFv, 2.6 d in mice and 7.9 d in cynomolgus monkeys, was equivalent to Fab'-PEG. PMID:27532598

  6. The SOC in cells’ living expectations of Conway’s Game of Life and its extended version

    International Nuclear Information System (INIS)

    Wei, Jinling; Zhou, Haiyan; Meng, Jun; Zhang, Fan; Chen, Yunmo; Zhou, Su

    2016-01-01

    In self-organized systems such as Conway’s Game of Life (CGL). Wikipedia, Conway’s game of the life, (https://en.wikipedia.org/wiki/Conway%27s#Low Line#Game_of_Life)., though whether the single cell will survive or die seems unpredictable, the log–log distribution of all cells living frequency satisfies the 1/f linear law, thus meets the Self-organized Criticality(SOC) rule, which not only proves that CGL is a self-organized system, but more significantly, that the chance of living for each cell is spatial heterogeneous, and is statistical fractal. After carried out CGL, the specified iterative period which begins with a random initial condition and ends when it reaches the homeostasis, add up all the states which the living cells are marked by 1s, and the dead are marked by 0s. The resulted sum picture consisting of cells having its gray level representing the living times during the iterative process. By plotting the gray level distribution of the sum picture on log–log scale, the graph indicates the spatial living expectations distributions. Then we find the curve of the graph satisfies the Self-organized Criticality(SOC) rule, showing its linear feature in the intermediate zone, which also has name of 1/f feature. To examine its universality, we designed a more complicated self-organized cellular automata with each cell having five possible states thus the rule table becomes more complicated. As expected, the consequence shows the similar feature, and the linear feature is even more obvious when the similar experiments are carried out. To conclude, it is a new discovery of SOC from a new perspective. And with the self-organized systems expanding to other different rule tables, this feature may still be satisfied. More further, considering the natural self-organized systems of living creatures, the spatial living expectations of different phenotypes may satisfy the 1/f law, too. Though we regard this as an inspirational orientation, the supposition needs

  7. The impact of chronic disease on orphans' quality of life living in extended social care services: a cross sectional analysis.

    Science.gov (United States)

    Alonazi, Wadi B

    2016-04-05

    Owing to a scarcity of data or other causes, patient research on the orphan population is lacking in most societies. Consequently, the primary goal of this study was to explore quality of life (QOL) and quality of care (QOC) among orphan patients (OPs) receiving tertiary healthcare services in Saudi Arabia (SA). This study used a cross-sectional, quantitative survey design. Participants included 216 OPs either currently undergoing or who had undergone treatment for common chronic diseases (CDs) (e.g. cardiovascular disease, cancer, stroke and arthritis) during the past 12 months. The survey utilised the brief form from the World Health Organization Quality of Life (WHOQOL-BREF) tool and evaluated healthcare access and effectiveness domains to scrutinise the socio-medical patterns of OPs based on their current medical episodes. The descriptive analysis indicated that OPs' overall QOL reached a moderate level (M = 3.90). Similarly, participants reported relatively high levels of healthcare access and treatment effectiveness (M = 4.14 and M = 4.29, respectively). Stroke patients reported the highest QOL score (M = 3.95), and groups of patients with other CDs reported greater access to healthcare and more effective treatment maintenance compared to the other groups (M = 4.19 and M = 4.43, respectively). Regression analysis was conducted to predict overall QOL based on perceived QOC, and access explained only 6.5 % of the variance. An analysis of variance showed significant differences only between OPs with cardiovascular disease and cancer (P = .001), with the former reporting better access to tertiary healthcare services than the latter. Although some CD patients reported relatively acceptable levels of access to healthcare and receipt of effective treatment, the improvement of OPs' QOL and QOC poses a serious challenge for health policymakers.

  8. Real-World Analysis of Dispensed IUs of Coagulation Factor IX and Resultant Expenditures in Hemophilia B Patients Receiving Standard Half-life Versus Extended Half-life Products and Those Switching from Standard Half-life to Extended Half-life Products.

    Science.gov (United States)

    Tortella, Bartholomew J; Alvir, José; McDonald, Margaret; Spurden, Dean; Fogarty, Patrick F; Chhabra, Amit; Pleil, Andreas M

    2018-01-24

    Hemophilia B requires replacement therapy with factor IX (FIX) coagulation products to treat and prevent bleeding episodes. A recently introduced extended half-life (EHL) recombinant FIX replacement product provided the opportunity to compare the amount of dispensed factor and expenditures for EHL treatment compared with a standard half-life (SHL) product. To determine factor international units (IUs) dispensed and expenditures associated with switching from nonacog alfa, the most commonly used SHL replacement product, to eftrenonacog alfa, an EHL FIX replacement product. Two U.S. claims databases were analyzed. A large national specialty pharmacy dispensation claims database was used to identify the number of IUs dispensed and monthly charges for all patients with hemophilia B from April 2015 to June 2016. Truven Health MarketScan Research Databases (January 2010-July 2016) were used to identify IUs and expenditures for patients with claims data for at least 3 months before and after switching from the SHL to the EHL product. Medians for IUs and expenditures are presented to accommodate for skewness of data distribution. The national specialty pharmacy database analysis included 296 patients with moderate or severe hemophilia B (233 on SHL; 94 on EHL). Median monthly factor dispensed was 11% lower (2,142 IU) in the EHL versus SHL cohort over the study period, while individual monthly reductions ranged from 32% to 47% (9,838 IU to 16,514 IU). Using the wholesale acquisition cost, the median per-patient monthly factor expenditures over the 15-month study period were 94% higher ($23,005) for the EHL than for the SHL product. Individual median monthly expenditure differences ranged from 15% ($6,562) to 49% ($19,624). In the Truven database, 14 patients switched from the SHL to the EHL product. The amount of factor dispensed was variable; in the 1-year period before and after the switch from the SHL to the EHL product, mean IUs dispensed decreased by 3,005 IU, while

  9. Radiation processing: An effective quality control tool for hygienization and extending shelf life of a herbal formulation, Amritamehari churnam

    Directory of Open Access Journals (Sweden)

    Suchandra Chatterjee

    2016-01-01

    Full Text Available Amritamehari churnam (AC is an antidiabetic polyherbal formulation constituting of four herbal medicinal plants namely Phyllanthus emblica, Salacia reticulata, Tinospora cordifolia and Curcuma longa. The feasibility of using gamma irradiation at doses between 2.5 and 10 kGy to reduce microbial load and enhance shelf life of this formulation was investigated. The irradiated and non-irradiated products were stored at room temperature (25–32 °C and 50–85% R.H., 1.5 years. Acceptability of the irradiated product was assessed based on sensory, microbial, physical and chemical attributes as well as their antioxidant status. A dose 7.5 kGy was sufficient to maintain microbial quality within acceptable limit up to 18 months of storage. No significant differences in sensory properties were observed between the non-irradiated and irradiated sample. The applied dose did not cause any significant qualitative and quantitative changes in the chemical constituents, antioxidant activities as well as physical properties when measured by EPR spectroscopy.

  10. Calculating the strength of water pipes for their rehabilitation with the application of polymer hoses

    Science.gov (United States)

    Primin, Oleg

    2017-10-01

    Such factors as: the growing deterioration and unsatisfactory technical condition of the pipes of water supply and wastewater disposal networks in Russian cities and other inhabited localities, as well as limited (under the conditions of Russian housing and utilities sector reforming) funding of pipeline renovation and rehabilitation have considerably aggravated the problem of pipe reliability provision. These factors make pipe renovation and rehabilitation quite a topical issue.A very promising trend in the field of pipeline construction and renovation named “trenchless technologies” has been commonly used in the world in recent years. As a result of this, a wide choice of different construction materials used for pipe rehabilitation appeared in the market. Under the conditions of densely built-up urban areas, these methods are of great current interest for city utilities. Quite different pipe renovation methods are used currently but the most popular method comprises the application of a flexible polymeric hose that makes it possible to form a new composite pipe inside the old one. The wall thickness of such a hose is among the important factors that have an impact on the cost and efficiency of pipe renovation methods based on the application of flexible polymeric hoses. The hose wall thickness is determined on the basis of calculating the “soil – old pipe – hose” system in view of its static stability. The article describes the technology for the trenchless rehabilitation of water pipes and the strength calculation method for a “pipe – polymeric hose” double-layer structure.

  11. The effect of a novel low temperature-short time (LTST) process to extend the shelf-life of fluid milk.

    Science.gov (United States)

    Myer, Phillip R; Parker, Kyle R; Kanach, Andrew T; Zhu, Tengliang; Morgan, Mark T; Applegate, Bruce M

    2016-01-01

    Pasteurization has long been the standard method to extend the shelf-life of dairy products, as well as a means to reduce microbial load and the risk of food-borne pathogens. However, the process has limitations, which include cost effectiveness, high energy input, and reduction of product quality/organoleptic characteristics. In an effort to reduce these limitations and extend shelf-life, this study examined a novel low temperature, short time (LTST) method in which dispersed milk in the form of droplets was treated with low heat/pressure variation over a short treatment time, in conjunction with pasteurization. Lactobacillus fermentum and Pseudomonas fluorescens Migula were exposed to conventional pasteurization treatments with and without LTST. Using these organisms, the LTST addition was able to reduce microbial load below detection limits; 1.0 × 10(1) cfu/mL, from approximately 1.2 × 10(8) and 1.0 × 10(7) cfu/mL for L. fermentum and P. fluorescens Migula, respectively. In addition, the shelf-life of the treated, raw, and uninoculated product was prolonged from 14 to 35 days, compared with standard pasteurization, to as long as 63 days with the LTST amendment. Sensory analysis of samples also demonstrated equal or greater preference for LTST + pasteurization treated milk when compared to pasteurization alone (α = 0.05). Conventional pasteurization was effective at reducing the above mentioned microorganisms by as much as 5.0 log10 cfu/mL. However, LTST was able to achieve 7.0-8.0 log10 cfu/mL reduction of the same microorganisms. In addition, BActerial Rapid Detection using Optical scattering Technology detected and identified microorganisms isolated both pre- and post-treatment, of which the only organisms surviving LTST were Bacillus spp. Increased lethality, improved shelf-life, and equal or better organoleptic characteristics without increased energy consumption demonstrate the effectiveness of the incorporation of LTST. The improved

  12. Domestic shower hose biofilms contain fungal species capable of causing opportunistic infection.

    Science.gov (United States)

    Moat, John; Rizoulis, Athanasios; Fox, Graeme; Upton, Mathew

    2016-10-01

    The domestic environment can be a source of pathogenic bacteria. We show here that domestic shower hoses may harbour potentially pathogenic bacteria and fungi. Well-developed biofilms were physically removed from the internal surface of shower hoses collected in four locations in England and Scotland. Amplicon pyrosequencing of 16S and 18S rRNA targets revealed the presence of common aquatic and environmental bacteria, including members of the Actinobacteria, Alphaproteobacteria, Bacteroidetes and non-tuberculous Mycobacteria. These bacteria are associated with infections in immunocompromised hosts and are widely reported in shower systems and as causes of water-acquired infection. More importantly, this study represents the first detailed analysis of fungal populations in shower systems and revealed the presence of sequences related to Exophiala mesophila, Fusarium fujikuroi and Malassezia restricta. These organisms can be associated with the environment and healthy skin, but also with infection in compromised and immuno-competent hosts and occurrence of dandruff. Domestic showering may result in exposure to aerosols of bacteria and fungi that are potentially pathogenic and toxigenic. It may be prudent to limit development of these biofilms by the use of disinfectants, or regular replacement of hoses, where immuno-compromised persons are present.

  13. The role of spices and lactic acid bacteria as antimicrobial agent to extend the shelf life of metata ayib (traditional Ethiopian spiced fermented cottage cheese).

    Science.gov (United States)

    Geremew, Tsehayneh; Kebede, Ameha; Andualem, Berhanu

    2015-09-01

    Spices and lactic acid bacteria have natural antimicrobial substances and organic compounds having antagonistic activity against microorganisms. The objective of this study was to investigate the role of spices and lactic acid bacteria as antimicrobial agent to extend the shelf life of metata ayib. Antimicrobial activities of spices and lactic acid bacteria (LAB) filtrates were determined by agar well diffusion method against E. coli, S. aureus, S. flexneri and S. peumoniae. Aantimicrobial activity of garlic was found to be the most effective against all the tested pathogens. Inhibition zones of garlic extract against all pathogens was significantly (P ≤ 0.05) greater than the remaining spice extracts. Inhibition zones (12.50 ± 1.00 to 15.50 ± 1.00 mm) of ginger and R. graveolens ethanol extracts against all tested pathogens were significantly (P ≤ 0.05) greater than the remaining solvent extracts. Inhibition zone of O. basilicum ethanol extract against all pathogenic bacteria was significantly (p ≤ 0.05) greater than hexane and acetone extracts. Lactobacillus isolates were shown the highest antimicrobial activity than the other LAB isolates against all pathogens. The synergistic effect of spices together with LAB might be contributed a lot to preserve and extend shelf life of metata ayib. Their antimicrobial activity can reduce the risk of spoilage and pathogenesis. The possible reason of LAB isolates was may be due to production of lactic acid, acetic acid and secondary metabolites like bacteriocins. Aseptic processing of traditional cottage cheese (ayib) is by far needed to minimize risks associated during consumption of metata ayib.

  14. Extending the half-life of a fab fragment through generation of a humanized anti-human serum albumin Fv domain: An investigation into the correlation between affinity and serum half-life.

    Science.gov (United States)

    Adams, Ralph; Griffin, Laura; Compson, Joanne E; Jairaj, Mark; Baker, Terry; Ceska, Tom; West, Shauna; Zaccheo, Oliver; Davé, Emma; Lawson, Alastair Dg; Humphreys, David P; Heywood, Sam

    2016-10-01

    We generated an anti-albumin antibody, CA645, to link its Fv domain to an antigen-binding fragment (Fab), thereby extending the serum half-life of the Fab. CA645 was demonstrated to bind human, cynomolgus, and mouse serum albumin with similar affinity (1-7 nM), and to bind human serum albumin (HSA) when it is in complex with common known ligands. Importantly for half-life extension, CA645 binds HSA with similar affinity within the physiologically relevant range of pH 5.0 - pH 7.4, and does not have a deleterious effect on the binding of HSA to neonatal Fc receptor (FcRn). A crystal structure of humanized CA645 Fab in complex with HSA was solved and showed that CA645 Fab binds to domain II of HSA. Superimposition with the crystal structure of FcRn bound to HSA confirmed that CA645 does not block HSA binding to FcRn. In mice, the serum half-life of humanized CA645 Fab is 84.2 h. This is a significant extension in comparison with albumin and serum half-life. Reduction in the affinity for MSA by 144-fold from 2.2 nM to 316 nM had no effect on serum half-life. Strikingly, despite a reduction in affinity to 62 µM, an extension in serum half-life of 26.4 h was still obtained. CA645 Fab and the CA645 Fab-HSA complex have been deposited in the Protein Data Bank (PDB) with accession codes, 5FUZ and 5FUO, respectively.

  15. Antimicrobial (BN/PE) film combined with modified atmosphere packaging extends the shelf life of minimally processed fresh-cut iceberg lettuce.

    Science.gov (United States)

    Kang, Sun-Chul; Kim, Min-Jeong; Park, In-Sik; Choi, Ung-Kyu

    2008-03-01

    This study was conducted to investigate the effect of modified atmosphere packaging (MAP) in combination with BN/PE film on the shelf life and quality of fresh-cut iceberg lettuce during cold storage. The total mesophilic population in the sample packed in BN/PE film under MAP conditions was dramatically reduced in comparison with that of PE film, PE film under MAP conditions, and BN/PE film. The O2 concentration in the BN/PE film under MAP conditions decreased slightly as the storage period progressed. The coloration of the iceberg lettuce progressed the slowest when it was packaged in BN/PE film under MAP conditions, followed by BN/PE film, PE film, and PE film under MAP conditions. The shelf life of fresh-cut iceberg lettuce packaged in the BN/PE film under MAP conditions was extended by more than 2 days at 10 degrees as compared with that of the BN/PE film in which the extension effect was more than 2 days longer than that of PE, PET, and OPP films.

  16. Conceptual Framework To Extend Life Cycle Assessment Using Near-Field Human Exposure Modeling and High-Throughput Tools for Chemicals.

    Science.gov (United States)

    Csiszar, Susan A; Meyer, David E; Dionisio, Kathie L; Egeghy, Peter; Isaacs, Kristin K; Price, Paul S; Scanlon, Kelly A; Tan, Yu-Mei; Thomas, Kent; Vallero, Daniel; Bare, Jane C

    2016-11-01

    Life Cycle Assessment (LCA) is a decision-making tool that accounts for multiple impacts across the life cycle of a product or service. This paper presents a conceptual framework to integrate human health impact assessment with risk screening approaches to extend LCA to include near-field chemical sources (e.g., those originating from consumer products and building materials) that have traditionally been excluded from LCA. A new generation of rapid human exposure modeling and high-throughput toxicity testing is transforming chemical risk prioritization and provides an opportunity for integration of screening-level risk assessment (RA) with LCA. The combined LCA and RA approach considers environmental impacts of products alongside risks to human health, which is consistent with regulatory frameworks addressing RA within a sustainability mindset. A case study is presented to juxtapose LCA and risk screening approaches for a chemical used in a consumer product. The case study demonstrates how these new risk screening tools can be used to inform toxicity impact estimates in LCA and highlights needs for future research. The framework provides a basis for developing tools and methods to support decision making on the use of chemicals in products.

  17. Effect of Rosmarinus officinalis L. essential oil combined with different packaging conditions to extend the shelf life of refrigerated beef meat.

    Science.gov (United States)

    Sirocchi, Veronica; Devlieghere, Frank; Peelman, Nanou; Sagratini, Gianni; Maggi, Filippo; Vittori, Sauro; Ragaert, Peter

    2017-04-15

    Rosemary essential oil (REO) contains bioactives having antioxidant and antimicrobial properties. This work investigated the effect of REO combined with modified atmosphere packaging conditions (MAP), in our case, aerobic, vacuum or high O 2 , to extend the shelf life of beef. Beef slices were wrapped in special three-layer sheets of packaging material, some with a coating of REO (active packaging, AP), and some without REO (non active packaging, NAP), and stored at 4°C for 20days. The use of REO proved efficacious in every storage condition, as seen in the lower counts of psychrotrophics, Brochothrix thermosphacta, Pseudomonas spp., and Enterobacteriaceae in AP meat compared to NAP meat. Sensory and colourimetric analyses showed that the best packaging conditions were high-O 2 atmosphere in combination with REO. Based on microbiological data, shelf life of beef was 5-6days for AP samples packaged under aerobic conditions and 14-15days for AP samples in high-O 2 conditions. Copyright © 2016 Elsevier Ltd. All rights reserved.

  18. Blocking performance of the hose model and the pipe model for VPN service provisioning over WDM optical networks

    Science.gov (United States)

    Wang, Haibo; Swee Poo, Gee

    2004-08-01

    We study the provisioning of virtual private network (VPN) service over WDM optical networks. For this purpose, we investigate the blocking performance of the hose model versus the pipe model for the provisioning. Two techniques are presented: an analytical queuing model and a discrete event simulation. The queuing model is developed from the multirate reduced-load approximation technique. The simulation is done with the OPNET simulator. Several experimental situations were used. The blocking probabilities calculated from the two approaches show a close match, indicating that the multirate reduced-load approximation technique is capable of predicting the blocking performance for the pipe model and the hose model in WDM networks. A comparison of the blocking behavior of the two models shows that the hose model has superior blocking performance as compared with pipe model. By and large, the blocking probability of the hose model is better than that of the pipe model by a few orders of magnitude, particularly at low load regions. The flexibility of the hose model allowing for the sharing of resources on a link among all connections accounts for its superior performance.

  19. An overview of the U.S. Department of Energy Program to extend the service life and operating license of nuclear powerplants

    International Nuclear Information System (INIS)

    Harrison, D.L.; Giessing, D.F.; McGoff, D.J.

    1992-01-01

    Today, 112 nuclear powerplants provide over 20 percent of the electrical energy generated in the United States. The operating license of the first of these plants will expire in the year 2000; one third of the operating licenses will expire by 2010 and the remaining plant licenses are scheduled to expire by 2031. The continued operation of these plants is essential to ensuring an adequate, diverse, and environmentally acceptable energy supply for economic growth and improved us competitiveness. In order to preserve this energy resource, three major tasks must be successfully completed: (1) establishment of the regulations, technical standards, and procedures for the preparation and review of license renewal applications; (2) development of the technical criteria and bases for needed monitoring, refurbishment, or replacement of plant equipment; and (3) demonstration of the regulatory process by a lead plant obtaining a renewed license. Since 1986, the Department of Energy (DOE) has been working with the nuclear industry and the safety regulator to establish and demonstrate by the end of 1995 the option to extend the life of nuclear powerplants through renewal of operating licenses. This paper provides an overview of the importance and role of license

  20. Combined Application of Antibrowning, Heat Treatment and Modified-Atmosphere Packaging to Extend the Shelf Life of Fresh-Cut Lotus Root.

    Science.gov (United States)

    Son, Jihye; Hyun, Jeong-Eun; Lee, Jo-Won; Lee, Sun-Young; Moon, BoKyung

    2015-06-01

    This work aimed to determine the effects of different concentrations of antibrowning treatments (that is, distilled water [DW], 1% ascorbic acid [AA], 0.5% chamomile [CM], and 1% AA + 0.5% CM) and heat-treatment (55 °C for 45 s) combined with packaging under 4 different modified-atmosphere gas compositions (that is, air, vacuum, 100% CO2 , 50% CO2 /50% N2 ) on the quality and microbiological characteristics of fresh-cut lotus root. The quality characteristics (that is, color, weight loss, texture, pH, polyphenoloxidase activity, and total phenolic content) of the AA + CM-dipped sample in 100% CO2 packaging were maintained significantly better than those of the other samples (P < 0.05). The microbiological counts observed in the DW-dipped sample during storage were higher than those of the AA, CM, and AA + CM samples, and heat-treatment retarded the microbiological deterioration of fresh-cut lotus root. Therefore, the results revealed that dipping in an antibrowning treatment (AA + CM), and 100% CO2 MAP with heat treatment effectively extend the shelf life of fresh-cut lotus root to 21 d at 5 °C. © 2015 Institute of Food Technologists®

  1. Potential of carboxymethyl cellulose coating and low dose gamma irradiation to maintain storage quality, inhibit fungal growth and extend shelf-life of cherry fruit.

    Science.gov (United States)

    Hussain, P R; Rather, S A; Suradkar, P; Parveen, S; Mir, M A; Shafi, F

    2016-07-01

    Carboxymethyl cellulose (CMC) coatings alone and in combination with gamma irradiation was tested for maintaining the storage quality, inhibiting fungal incidence and extending shelf-life of cherry fruit. Two commercial cherry varieties viz. Misri and Double after harvest at commercial maturity were coated with CMC at levels 0.5-1.0 % w/v and gamma irradiated at 1.2 kGy. The treated fruit including control was stored under ambient (temperature 25 ± 2 °C, RH 70 %) and refrigerated (temperature 3 ± 1 °C, RH 80 %) conditions for evaluation of various physico-chemical parameters. Fruits were evaluated after every 3 and 7 days under ambient and refrigerated conditions. CMC coating alone at levels 0.5 and 0.75 % w/v was not found effective with respect to mold growth inhibition under either of the two conditions. Individual treatment of CMC coating at 1.0 % w/v and 1.2 kGy irradiation proved helpful in delaying the onset of mold growth up to 5 and 8 days of ambient storage. During post-refrigerated storage at 25 ± 2 °C, RH 70 %, irradiation alone at 1.2 kGy gave further 4 days extension in shelf-life of cherry varieties following 28 days of refrigeration. All combinatory treatments of CMC coating and irradiation proved beneficial in maintaining the storage quality as well as delaying the decaying of cherry fruit during post-refrigerated storage at 25 ± 2 °C, RH 70 % but, combination of CMC at 1.0 % w/v and 1.2 kGy irradiation was found significantly ( p  ≤ 0.05) superior to all other treatments in maintaining the storage quality and delaying the decaying of cherry fruit. The above combinatory treatment besides maintaining storage quality resulted in extension of 6 days in shelf life of cherry varieties during post-refrigerated storage at 25 ± 2 °C, RH 80 % following 28 days of refrigeration. Above Combination treatment gave a maximum of 2.3 and 1.5 log reduction in yeast and mold count of cherry fruits after 9 and 28

  2. Optimization of the Manufacturing Process of Zr-2.5Nb Pressure Tubes for CANDU Reactors for Extending Their Design Life to Over 30 years

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Young Suk [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2007-10-15

    Zr-2.5Nb pressure tubes are the most critical components that determine the design life of CANADU (CAnadian Natural Uranium) reactors. The initial design target for the Zr-2.5Nb pressure tubes is to suppress the diametral creep through a texture control which may trade off the other performances that can be overcome by introducing a change in the components design. To this end, they are made by the extrusion process at high temperatures to have a circumferential texture with most of the basal poles oriented towards their circumferential direction. However, this circumferential texture causes them to be very susceptible to delayed hydride cracking (DHC) and to have a higher axial elongation. Against the initial design target, their costly refurbishments are planned in several commercial CANDU reactors before their design life of 30 years, due to the unexpectedly faster creep rate and axial elongation. This fact casts a question over the validity of the design philosophy that the diametral creep of the Zr-2.5Nb pressure tube is governed by the texture. The aim of this work is to elucidate the governing factor of creep of the Zr-2.5Nb tubes and to find a way of making improved Zr-2.5Nb pressure tubes with a lower diametral creep and axial elongation. To this end, we scrutinized Holt's experiment where the in-reactor creep behaviors of the Zr-2.5Nb micro-pressure tube (MPT) with a circumferential texture was compared with that of the Zr-2.5Nb fuel sheath (FS) with a radial texture. Accounting for the fact that thermal creep of Zr-2.5Nb alloy is affected by the Nb concentration in the {beta}-Zr, we demonstrate that the reduced creep is not dictated by the circumferential texture but by the increased Nb concentration in the {alpha}-Zr. This study suggests that the optimized manufacturing procedure of the Zr-2.5Nb tube would improve their in-reactor performances, extending their design life to over 30 years when compared to that of the current design of the

  3. Potential of carboxymethyl cellulose coating and low dose gamma irradiation to maintain storage quality, inhibit fungal growth and extend shelf-life of cherry fruit

    International Nuclear Information System (INIS)

    Hussain, P.R.; Rather, S.A.; Suradkar, P.; Parveen, S.; Mir, M.A.; Shafi, F.

    2016-01-01

    Carboxymethyl cellulose (CMC) coatings alone and in combination with gamma irradiation was tested for maintaining the storage quality, inhibiting fungal incidence and extending shelf-life of cherry fruit. Two commercial cherry varieties viz. Misri and Double after harvest at commercial maturity were coated with CMC at levels 0.5-1.0 % w/v and gamma irradiated at 1.2 kGy. The treated fruit including control was stored under ambient (temperature 25± 2 °C, RH 70 %) and refrigerated (temperature 3±1 °C, RH 80 %) conditions for evaluation of various physico-chemical parameters. Fruits were evaluated after every 3 and 7 days under ambient and refrigerated conditions. CMC coating alone at levels 0.5 and 0.75 % w/v was not found effective with respect to mold growth inhibition under either of the two conditions. Individual treatment of CMC coating at 1.0 % w/v and 1.2 kGy irradiation proved helpful in delaying the onset of mold growth up to 5 and 8 days of ambient storage. During post-refrigerated storage at 25±2 °C, RH 70 %, irradiation alone at 1.2 kGy gave further 4 days extension in shelf-life of cherry varieties following 28 days of refrigeration. All combinatory treatments of CMC coating and irradiation proved beneficial in maintaining the storage quality as well as delaying the decaying of cherry fruit during post-refrigerated storage at 25±2 °C, RH 70 % but, combination of CMC at 1.0 % w/v and 1.2 kGy irradiation was found significantly (p≤0.05) superior to all other treatments in maintaining the storage quality and delaying the decaying of cherry fruit. The above combinatory treatment besides maintaining storage quality resulted in extension of 6 days in shelf life of cherry varieties during post-refrigerated storage at 25±2 °C, RH 80 % following 28 days of refrigeration. Above combination treatment gave a maximum of 2.3 and 1.5 log reduction in yeast and mold count of cherry fruits after 9 and 28 days of ambient and refrigerated storage, thereby

  4. The Extended Enterprise concept

    DEFF Research Database (Denmark)

    Larsen, Lars Bjørn; Vesterager, Johan; Gobbi, Chiara

    1999-01-01

    This paper provides an overview of the work that has been done regarding the Extended Enterprise concept in the Common Concept team of Globeman 21 including references to results deliverables concerning the development of the Extended Enterprise concept. The first section presents the basic concept...... picture from Globeman21, which illustrates the Globeman21 way of realising the Extended Enterprise concept. The second section presents the Globeman21 EE concept in a life cycle perspective, which to a large extent is based on the thoughts and ideas behind GERAM (ISO/DIS 15704)....

  5. Fracture Rate, Quality of Life and Back Pain in Patients with Osteoporosis Treated with Teriparatide: 24-Month Results from the Extended Forsteo Observational Study (ExFOS).

    Science.gov (United States)

    Langdahl, Bente L; Ljunggren, Östen; Benhamou, Claude-Laurent; Marin, Fernando; Kapetanos, George; Kocjan, Tomaz; Lespessailles, Eric; Napoli, Nicola; Nikolic, Tatjana; Petto, Helmut; Moll, Thomas; Lindh, Erik

    2016-09-01

    We describe the pre-planned interim analysis of fracture outcomes, health-related quality of life (HRQoL) and back pain in patients with severe osteoporosis treated with teriparatide for up to 24 months in the Extended Forsteo (Forsteo(®) is a registered trade name of Eli Lilly and Company) Observational Study (ExFOS), a prospective, multinational, observational study. Data on incident clinical fractures, HRQoL (EQ-5D questionnaire) and back pain [100 mm visual analogue scale (VAS)] were collected. The number of patients with fractures was summarised in 6-month intervals and fracture rate over each 6-month period was assessed using logistic regression for repeated measures. Changes from baseline in EQ-5D and back pain VAS were analysed using mixed models for repeated measures. Of 1454 patients in the active treatment cohort, 90.6 % were female and 14.4 % were taking glucocorticoids. During teriparatide treatment (median duration 23.7 months), 103 patients (7.1 %) sustained a total of 122 incident clinical fractures (21 % vertebral, 79 % non-vertebral). A 49 % decrease in the odds of fractures and a 75 % decrease in the odds of clinical vertebral fractures were observed in the >18- to 24-month period versus the first 6-month period (both p teriparatide treatment. In conclusion, patients with severe osteoporosis showed a significant reduction in the incident fracture rate during 24 months of teriparatide treatment in routine clinical practice, accompanied by a significant improvement in HRQoL and reduction in back pain. Results should be interpreted in the context of the non-controlled design of this observational study.

  6. The Calculation of the Tracking Force in the Evolution of the Resistive Hose Instability of a Relativistic Electron Beam

    Science.gov (United States)

    Kolesnikov, E. K.; Manuilov, A. S.; Petrov, V. S.

    2018-01-01

    We have analyzed the tacking force exerted by a low-conductivity Ohmic plasma channel on a relativistic electron beam. It has been shown that, for the given type of evolution of the resistive hose instability of the beam along its pulse, this force substantially depends on the frequency and the increment of the increase in the given instability.

  7. Extended Emotions

    DEFF Research Database (Denmark)

    Krueger, Joel; Szanto, Thomas

    2016-01-01

    Until recently, philosophers and psychologists conceived of emotions as brain- and body-bound affairs. But researchers have started to challenge this internalist and individualist orthodoxy. A rapidly growing body of work suggests that some emotions incorporate external resources and thus extend...... beyond the neurophysiological confines of organisms; some even argue that emotions can be socially extended and shared by multiple agents. Call this the extended emotions thesis (ExE). In this article, we consider different ways of understanding ExE in philosophy, psychology, and the cognitive sciences....... First, we outline the background of the debate and discuss different argumentative strategies for ExE. In particular, we distinguish ExE from cognate but more moderate claims about the embodied and situated nature of cognition and emotion (Section 1). We then dwell upon two dimensions of ExE: emotions...

  8. Extended thermodynamics

    CERN Document Server

    Müller, Ingo

    1993-01-01

    Physicists firmly believe that the differential equations of nature should be hyperbolic so as to exclude action at a distance; yet the equations of irreversible thermodynamics - those of Navier-Stokes and Fourier - are parabolic. This incompatibility between the expectation of physicists and the classical laws of thermodynamics has prompted the formulation of extended thermodynamics. After describing the motifs and early evolution of this new branch of irreversible thermodynamics, the authors apply the theory to mon-atomic gases, mixtures of gases, relativistic gases, and "gases" of phonons and photons. The discussion brings into perspective the various phenomena called second sound, such as heat propagation, propagation of shear stress and concentration, and the second sound in liquid helium. The formal mathematical structure of extended thermodynamics is exposed and the theory is shown to be fully compatible with the kinetic theory of gases. The study closes with the testing of extended thermodynamics thro...

  9. How the analysis of genetic mutations can help us to solve basic problems in gerontology? II. Life extending genetic modifications in budding yeast S. cereviseae, fruit fly D. melanogaster and laboratory mice M. musculus.

    Science.gov (United States)

    Khalyavkin, A V; Yashin, A I

    2003-01-01

    Most studies of aging are conducted in humans and domestic or laboratory animals, i.e. in conditions where artificial environment protection is applied, This yields changes in physiology and behavior, which set up organism's state unobserved in wild life. This state may be less adequate to the evolutionary adjusted genetic construction of an organism, which generates a hypothesis that in natural niches the aging rate can be lower and stress resistance can be higher than in captivity despite the fact that life expectancy in habitat is essentially lower than that in laboratory conditions due to high external mortality. Direct test of this hypothesis is difficult because of problems related to reconstruction of natural environment conditions in the laboratory. Substantial life-extending effect of some mutated genes can serve as indirect test of the hypothesis. We propose that in some cases genetic mutations can distort reaction of an organism on environmental cues and change control parameters of its life cycle. As a result such mutants in laboratory may partly demonstrate life traits similar to those observed in natural environment, e.g. associated with high stress resistance and low rate of aging. These features combined with low external mortality in laboratory conditions may lead to significant extension in the life span of mutants. Recently we considered 56 life-extending gene modifications in nematode C. elegans (Adv. Gerontol., 2003, Vol. 11), scattered in many publications. In this paper we consider pertinent life-extending gene modifications corresponded to the budding yeast S. cerevisease (29 genes), fruit fly D. melanogaster (22 genes) and laboratory mice M. musculus (8 genes).

  10. Extended ERP

    OpenAIRE

    Müssigmann, Nikolaus

    2005-01-01

    Extended ERP : dynamic strategic supply network development / A. Albani, N. Müssigmann, K. Turowski. - In: ICESAcc 2005 - Second International Conference on Enterprise Systems and Accounting / C. J. Stefanou. - Thessaloniki : Labor. of Enterprise Resources Dep. of Accounting, 2005. - 1 CD-ROM

  11. Replacement for a Flex Hose Coating at the Space Shuttle Launch Pad

    Science.gov (United States)

    Whitten, Mary; Vinje, Rubiela; Curran, Jerome; Meneghelli, Barry; Calle, Luz Marina

    2009-01-01

    Aerocoat AR-7 is a coating that has been used to protect stainless steel flex hoses at NASA's Kennedy Space Center launch complex and hydraulic lines of the mobile launch platform (MLP). This coating has great corrosion control performance and low temperature application. AR-7 was developed by NASA and produced exclusively for NASA but its production has been discontinued due to its high content of volatile organic compounds (VOC) and significant environmental impact. The purpose of this project was to select and evaluate candidate coatings to find a replacement coating that is more environmentally friendly, with similar properties to AR-7. No coatings were identified that perform the same as AR-7 in all areas. Candidate coatings failed in comparison to AR-7 in salt fog, beachside atmospheric exposure, pencil hardness, Mandrel bend, chemical compatibility, adhesion, and ease of application tests. However, two coatings were selected for further evaluation.

  12. Blocking probability in the hose-model optical VPN with different number of wavelengths

    Science.gov (United States)

    Roslyakov, Alexander V.

    2017-04-01

    Connection setup with guaranteed quality of service (QoS) in the optical virtual private network (OVPN) is a major goal for the network providers. In order to support this we propose a QoS based OVPN connection set up mechanism over WDM network to the end customer. The proposed WDM network model can be specified in terms of QoS parameter such as blocking probability. We estimated this QoS parameter based on the hose-model OVPN. In this mechanism the OVPN connections also can be created or deleted according to the availability of the wavelengths in the optical path. In this paper we have considered the impact of the number of wavelengths on the computation of blocking probability. The goal of the work is to dynamically provide a best OVPN connection during frequent arrival of connection requests with QoS requirements.

  13. Application of low-dose gamma irradiation to extend the shelf life of minimally processed Red Beet (Beta vulgaris sp. vulgaris L.), cv. Early Wonder

    International Nuclear Information System (INIS)

    Hernandez, Nilber Kenup

    2006-01-01

    detected independently of the dose. In addition, physicochemical analyses investigated the evolution of pH; total acidity; total soluble solids and ascorbic acid throughout storage. Samples from experiment 2 were also subjected to sensory analyses for overall appearance and aroma at 4 different post-irradiation times. The results indicated that the samples irradiated with 1.0 and 1.5 kGy remained good for consumption for 20 days. Therefore it can be concluded that the application of those doses extended the shelf life of the samples without harming their nutritional and sensory quality. Finally, the results indicate that the dose of 1.0 kGy is the most appropriate for the conservation of red beet among those tested. (author)

  14. Extending Puppet

    CERN Document Server

    Franceschi, Alessandro

    2014-01-01

    This book is a clear, detailed and practical guide to learn about designing and deploying you puppet architecture, with informative examples to highlight and explain concepts in a focused manner. This book is designed for users who already have good experience with Puppet, and will surprise experienced users with innovative topics that explore how to design, implement, adapt, and deploy a Puppet architecture. The key to extending Puppet is the development of types and providers, for which you must be familiar with Ruby.

  15. RCRA Facility Investigation/Remedial Investigation Report with Baseline Risk Assessment for the Fire Department Hose Training Facility (904-113G)

    Energy Technology Data Exchange (ETDEWEB)

    Palmer, E. [Westinghouse Savannah River Company, AIKEN, SC (United States)

    1997-04-01

    This report documents the Resource Conservation and Recovery Act (RCRA) Facility Investigation/Remedial Investigation/Baseline Risk Assessment (RFI/RI/BRA) for the Fire Department Hose Training Facility (FDTF) (904-113G).

  16. Application of Pharmacokinetics and Pharmacodynamics in Product Life Cycle Management. A Case Study with a Carbidopa-Levodopa Extended-Release Formulation.

    Science.gov (United States)

    Modi, Nishit B

    2017-05-01

    Increasing costs in discovering and developing new molecular entities and the continuing debate on limited company pipelines mean that pharmaceutical companies are under significant pressure to maximize the value of approved products. Life cycle management in the context of drug development comprises activities to maximize the effective life of a product. Life cycle approaches can involve new formulations, new routes of delivery, new indications or expansion of the population for whom the product is indicated, or development of combination products. Life cycle management may provide an opportunity to improve upon the current product through enhanced efficacy or reduced side effects and could expand the therapeutic market for the product. Successful life cycle management may include the potential for superior efficacy, improved tolerability, or a better prescriber or patient acceptance. Unlike generic products where bioequivalence to an innovator product may be sufficient for drug approval, life cycle management typically requires a series of studies to characterize the value of the product. This review summarizes key considerations in identifying product candidates that may be suitable for life cycle management and discusses the application of pharmacokinetics and pharmacodynamics in developing new products using a life cycle management approach. Examples and a case study to illustrate how pharmacokinetics and pharmacodynamics contributed to the selection of dosing regimens, demonstration of an improved therapeutic effect, or regulatory approval of an improved product label are presented.

  17. Consciousness extended

    DEFF Research Database (Denmark)

    Carrara-Augustenborg, Claudia

    2012-01-01

    There is no consensus yet regarding a conceptualization of consciousness able to accommodate all the features of such complex phenomenon. Different theoretical and empirical models lend strength to both the occurrence of a non-accessible informational broadcast, and to the mobilization of specific...... brain areas responsible for the emergence of the individual´s explicit and variable access to given segments of such broadcast. Rather than advocating one model over others, this chapter proposes to broaden the conceptualization of consciousness by letting it embrace both mechanisms. Within...... such extended framework, I propose conceptual and functional distinctions between consciousness (global broadcast of information), awareness (individual´s ability to access the content of such broadcast) and unconsciousness (focally isolated neural activations). My hypothesis is that a demarcation in terms...

  18. Parallel and oblique proton fire hose instabilities in the presence of alpha/proton drift: Hybrid simulations

    Czech Academy of Sciences Publication Activity Database

    Hellinger, Petr; Trávníček, Pavel

    2006-01-01

    Roč. 111, č. A1 (2006), A01107/1-A01107/7 ISSN 0148-0227 R&D Projects: GA AV ČR IAA3042403 Grant - others:ESA(XE) PECS 98024 Institutional research plan: CEZ:AV0Z30420517 Keywords : proton temperature anisotropy * fire hose instability * hybrid simulations Subject RIV: DG - Athmosphere Sciences, Meteorology Impact factor: 2.800, year: 2006

  19. Complex investigations for the technical diagnosis and constructive optimization of the pipe systems from Rovinari power plant to extend their remaining life

    Energy Technology Data Exchange (ETDEWEB)

    Delamarian, C. [Technischer Ueberwachungs-Verein Sueddeutschland (TUeV), Muenchen (Germany); Lupescu, L.; Nicolescu, N. [Institutul de Studii si Proiectari Energetice, Bucharest (Romania); Pisc, I.; Botis, A. [ISIM, Timisoara (Romania)

    2003-07-01

    The remnant life assessment of power plant components is an issue of a high importance all over the Europe and not only. The need of power products, the environmental-related restrictions within this field as well as the task of lowering the fabrication costs led to and increased importance of maintenance and retrofit activities of old power equipment during the last decade. Replacement of pipe lines exceeding their designed life is no longer regarded as an option for power plant managers. Instead, life assessment techniques combined with state of the art design and fabrication methods focusing on the replacement of damaged components as well as redesign of pipe line systems in order to eliminate overloading and/or secondary stresses that usually lead to premature life exhaustion are only some of the issues discussed within this paper. It deals with the retrofit of a conventional power plant (Group no. 3 of Rovinari Power Plant) which reached its designed life after about 110.000 operating hours. The need of improvement of the boiler efficiency as well as the extension of the plant life, maintaining in the same time old, but still good components determined the three companies (ISPE, ISIM and TUeV) to gather their skills in order to reach this task. (orig.)

  20. Evaluation of candidate alloys for the construction of metal flex hoses in the STS launch environment

    Science.gov (United States)

    Ontiveros, Cordelia

    1988-01-01

    Various vacuum jacketed cryogenic supply lines at the Shuttle launch site use convoluted flexible expansion joints. The atmosphere at the launch site has a very high salt content, and during a launch, fuel combustion products include hydrochloric acid. This extremely corrosive environment has caused pitting corrosion failure in the flex hoses, which were made of 304L stainless steel. A search was done to find a more corrosion resistant replacement material. This study focused on 19 metal alloys. Tests which were performed include electrochemical corrosion testing, accelerated corrosion testing in a salt fog chamber, long term exposure at the beach corrosion testing site, and pitting corrosion tests in ferric chloride solution. Based on the results of these tests, the most corrosion resistant alloys were found to be (in order) Hastelloy C-22, Inconel 625, Hastelloy C-276, Hastelloy C-4, and Inco Alloy G-3. Of these top five alloys, the Hastelloy C-22 stands out as being the best of those tested for this application.

  1. Life Cycle Thinking and Integrated Product Deliveries in renovation projects: Extending the concept of Integrated Product Deliveries with Product Service Systems

    DEFF Research Database (Denmark)

    Schipull Kauschen, Jan

    2012-01-01

    of building components. APPROACH AND DISCUSSION The Danish building stock with its specifically high allocation of multi-storey social housing blocks from the 1960s and 70s, built mainly from prefabricated, modularized concrete elements in combination with new low energy building regulations creates a great...... IPDs with regard to longevity and adaptability. CONCLUSION The new type of service-focused IPD and the related life-cycle responsibility (development, building phase, maintenance and dismantling/adaption/recycling) creates incentive to integrate life cycle thinking into the development process of IPDs...

  2. Application of modified atmosphere packaging (gas flushing and active packaging) for extending the shelf life of Beauveria bassiana conidia at high temperatures

    Science.gov (United States)

    Limited shelf life has long been a major constraint to the development of fungus-based bioinsecticides (mycoinsecticides). Fungal spores comprising the active ingredients of most products typically lose viability within a few months when stored in conventional packaging at temperatures >30 deg C. Me...

  3. Is “end of life” a special case? Connecting Q with survey methods to measure societal support for views on the value of life-extending treatments

    NARCIS (Netherlands)

    H. Mason (Helen); M. Collins (Marissa); N. McHugh (Neil); Godwin, J. (Jon); N.J.A. van Exel (Job); C.R. Donaldson (Cam); R.M. Baker (Rachel)

    2018-01-01

    textabstractPreference elicitation studies reporting societal views on the relative value of end-of-life treatments have produced equivocal results. This paper presents an alternative method, combining Q methodology and survey techniques (Q2S) to determine the distribution of 3 viewpoints on the

  4. Potential Use of a Weak Ethylene Receptor Mutant, Sletr1-2, as Breeding Material To Extend Fruit Shelf Life of Tomato.

    Science.gov (United States)

    Mubarok, Syariful; Okabe, Yoshihiro; Fukuda, Naoya; Ariizumi, Tohru; Ezura, Hiroshi

    2015-09-16

    Mutations in the ethylene receptor gene (SlETR1), Sletr1-1 and Sletr1-2, are effective in reducing ethylene sensitivity and improving fruit shelf life. In this study the effect of Sletr1-1 and Sletr1-2 mutations was investigated in F1 hybrid lines. These two mutants and control were crossed with four commercial pure-line tomatoes. The Sletr1-1 mutation showed undesirable pleiotropic effects in the F1 hybrid lines. The Sletr1-2 mutation was effective in improving fruit shelf life of F1 hybrid lines for 4-5 days longer. It was also effective in improving fruit firmness without change in fruit size, ethylene production, respiration rate, and total soluble solids or a great reduction in fruit color, lycopene, and β-carotene, although the titratable acidity was increased by Sletr1-2 mutation. These results indicate that the Sletr1-2 mutant allele has the potential to improve fruit shelf life via incorporation in tomato breeding programs.

  5. Synergetic effect of combined fumaric acid and slightly acidic electrolysed water on the inactivation of food-borne pathogens and extending the shelf life of fresh beef.

    Science.gov (United States)

    Tango, C-N; Mansur, A-R; Kim, G-H; Oh, D-H

    2014-12-01

    To evaluate synergetic effect of slight acidic electrolysed water (SAEW) and fumaric acid (FA) on inactivation of total viable count (TVC) and Staphylococcus aureus, Listeria monocytogenes, Escherichia coli O157:H7 and Salmonella Typhimurium in fresh beef and to study shelf life and sensory quality of beef. Inoculated samples was dipped for 1, 3 and 5 min and immersed at 25, 40 and 60°C in SAEW, strong acidic electrolysed water (StAEW) and SAWE + FA. Treated meat was air-packaged and stored at 4 or 10°C. During storage, sampling was performed at 2-day intervals for microbiological and sensory changes. TVC was decontaminated at 40°C for 3 min by more than 3·70 log CFU g(-1) , and examined pathogens were reduced by more than 2·60 log CFU g(-1) with SAEW + FA treatment. This treatment prolonged shelf life of beef meat up to 9 and 7 days when stored at 4 and 10°C, respectively. The combined treatment of SAEW + FA showed greater bactericidal effect and prolonged shelf life compared with individual treatments. Combined treatment of SAEW and FA can be a suitable hurdle technology reducing bacteria in fresh beef, substantially enhancing their microbial safety and decreasing pathogens growth during storage. © 2014 The Society for Applied Microbiology.

  6. Development of short questionnaire to measure an extended set of role expectation conflict, coworker support and work-life balance: The new job stress scale

    Directory of Open Access Journals (Sweden)

    Abhishek Shukla

    2016-12-01

    Full Text Available This study aimed to investigate the reliability and validity of a new version of job stress scale, which measures the extended set of psychosocial stressors by adding new scales to the current version of the job stress scale. Additional scales were extensively collected from theoretical job stress models and similar questionnaire from different countries. Items were tested in workplace and refined through a pilot survey (n = 400 to examine the reliability and construct validity. Most scales showed acceptable levels of internal consistency, intra-class reliability, and test–retest reliability. Factor analysis and correlation analysis showed that these scales fit the theoretical expectations. These findings provided enough evidences that the new job stress scale is reliable and valid. Although confirmatory analysis should be examined in future studies. The new job stress scale is a useful instrument for organization and academicians to evaluate job stress in modern Indian workplace.

  7. Low-dose gamma irradiation following hot Water immersion of Papaya (Carica Papaya linn.) fruits provides additional control of postharvest fungal infection to extend shelf life

    DEFF Research Database (Denmark)

    Rashid, M.H.A.; Grout, Brian William Wilson; Continella, A.

    2015-01-01

    Low-dose gamma irradiation (0.08 kGy over 10 min), a level significantly below that required to satisfy the majority of international quarantine regulations, has been employed to provide a significant reduction in visible fungal infection on papaya fruit surfaces. This is appropriate for local...... and national markets in producer countries where levels of commercial acceptability can be retained despite surface lesions due to fungal infection. Irradiation alone and in combination with hot-water immersion (50 °C for 10 min) has been applied to papaya (Carica papaya L.) fruits at both the mature green...... and 1/3 yellow stages of maturity. The incidence and severity of surface fungal infections, including anthracnose, were significantly reduced by the combined treatment compared to irradiation or hot water treatment alone, extending storage at 11 °C by 13 days and retaining commercial acceptability...

  8. Ion-hose instability in a long-pulse linear induction accelerator

    Directory of Open Access Journals (Sweden)

    Thomas C. Genoni

    2003-03-01

    Full Text Available The ion-hose instability is a transverse electrostatic instability which occurs on electron beams in the presence of a low-density ion channel. It is a phenomenon quite similar to the interaction between electron clouds and proton or positron beams in high-energy accelerators and storage rings. In the DARHT-2 accelerator, the 2-kA, 2-μs beam pulse produces an ion channel through impact ionization of the residual background gas (10^{-7}–10^{-6}   torr. A calculation of the linear growth by Briggs indicates that the instability could be strong enough to affect the radiographic application of DARHT, which requires that transverse oscillations be small compared to the beam radius. We present semianalytical theory and 3D particle-in-cell simulations (using the Lsp code of the linear and nonlinear growth of the instability, including the effects of the temporal change in the ion density and spatially decreasing beam radius. We find that the number of e-foldings experienced by a given beam slice is given approximately by an analytic expression using the local channel density at the beam slice. Hence, in the linear regime, the number of e-foldings increases linearly from head to tail of the beam pulse since it is proportional to the ion density. We also find that growth is strongly suppressed by nonlinear effects at relatively small oscillation amplitudes of the electron beam. This is because the ion oscillation amplitude is several times larger than that of the beam, allowing nonlinear effects to come into play. An analogous effect has recently been noted in electron-proton instabilities in high-energy accelerators and storage rings. For DARHT-2 parameters, we find that a pressure of ≤1.5×10^{-7}   torr is needed to keep the transverse beam oscillation amplitude less than about 20% of the rms beam radius.

  9. Suppression of two-stream hose instabilities at wavelengths shorter than the beam’s transverse size

    Directory of Open Access Journals (Sweden)

    R. A. Bosch

    2003-07-01

    Full Text Available Transverse hose instability may disrupt the propagation of a charged-particle beam in a channel of oppositely charged particles. A theoretical model predicts stabilization of this two-stream instability when the instability wavelength becomes smaller than the beam’s transverse size in a frame of reference where the instability’s phase velocity is nonrelativistic. Suppression of short-wavelength instability is also predicted when a proton beam propagates through a channel consisting of electrons and positive ions, consistent with previous experimental results.

  10. Low-dose gamma irradiation following hot water immersion of papaya (Carica papaya linn.) fruits provides additional control of postharvest fungal infection to extend shelf life

    Science.gov (United States)

    Rashid, M. H. A.; Grout, B. W. W.; Continella, A.; Mahmud, T. M. M.

    2015-05-01

    Low-dose gamma irradiation (0.08 kGy over 10 min), a level significantly below that required to satisfy the majority of international quarantine regulations, has been employed to provide a significant reduction in visible fungal infection on papaya fruit surfaces. This is appropriate for local and national markets in producer countries where levels of commercial acceptability can be retained despite surface lesions due to fungal infection. Irradiation alone and in combination with hot-water immersion (50 °C for 10 min) has been applied to papaya (Carica papaya L.) fruits at both the mature green and 1/3 yellow stages of maturity. The incidence and severity of surface fungal infections, including anthracnose, were significantly reduced by the combined treatment compared to irradiation or hot water treatment alone, extending storage at 11 °C by 13 days and retaining commercial acceptability. The combined treatment had no significant, negative impact on ripening, with quality characteristics such as surface and internal colour change, firmness, soluble solids, acidity and vitamin C maintained at acceptable levels.

  11. Au-coated carbon electrodes for aprotic Li-O2 batteries with extended cycle life: The key issue of the Li-ion source

    Science.gov (United States)

    Balasubramanian, P.; Marinaro, M.; Theil, S.; Wohlfahrt-Mehrens, M.; Jörissen, L.

    2015-03-01

    Despite having the capability of achieving high energy densities, Li-O2 batteries still suffer from many inherent disadvantages such as electrolyte stability, sluggish kinetics of the oxygen reduction/evolution reactions in the aprotic environment and electrodes stability. Our research demonstrates by combining electrochemical and analytical techniques that the performances of Li-O2 batteries based on LiTFSI-Tetraglyme electrolyte and Au-coated carbon electrodes are manly hindered by the instability of the lithium metal anode in the oxygen-saturated environment. Although the Au-coated carbon electrodes are able to minimize side reactions arising from electrolyte decomposition, oxygen crossover on the lithium metal results in the formation of decomposition products (LiOH, Li2CO3) that are clearly detrimental for the battery performance. Finally it is demonstrated that the Au-coated carbon electrodes in combination with the LiTFSI-Tetraglyme electrolyte can sustain extended cycling (100 cycles) when a more stable source of Li-ion, namely lithium iron phosphate (LFP), is used.

  12. Evaluation of Quality of Life, Functioning, Disability, and Work/School Productivity Following Treatment with an Extended-Release Hydrocodone Tablet Formulated with Abuse-Deterrence Technology: A 12-month Open-label Study in Patients with Chronic Pain.

    Science.gov (United States)

    Hale, Martin E; Zimmerman, Thomas R; Ma, Yuju; Malamut, Richard

    2017-02-01

    This phase 3 study evaluated quality of life, functioning, and productivity after treatment with extended-release (ER) hydrocodone formulated with CIMA ® Abuse-Deterrence Technology platform. Patients with chronic pain were rolled over from a 12-week placebo-controlled hydrocodone ER study or were newly enrolled. Hydrocodone ER doses were titrated (15 to 90 mg every 12 hours) to an analgesic dose, and patients received up to 52 weeks of open-label treatment. Assessments included Clinician Assessment of Patient Function (CAPF), Patient Assessment of Function (PAF), Brief Pain Inventory-Short Form (BPI-SF), 36-item Short-Form Health Survey (SF-36), Sheehan Disability Scale (SDS), and World Health Organization Health and Work Performance Questionnaire-Short Form (HPQ-SF). Of 330 enrolled patients, 291 composed the full analysis population. By week 4, ≥ 50% of patients showed improvement from baseline in all 5 CAPF domains (general activities, walking, work/daily living, relationships, and enjoyment of life) and 6 of 7 PAF domains (work attendance, work performance, walking, exercise, socializing, and enjoying life). Mean decreases from baseline of 2 to 3 points were noted for BPI-SF pain interference questions from week 4 through endpoint. Mean improvements from baseline to endpoint in SF-36 subscales ranged from 3.3 to 22.3, and SDS scores improved from moderate (4.8 to 5.1) to mild (2.5 to 2.8) disruptions in work/school, social life, and family life. At endpoint, mean HPQ-SF absolute absenteeism scores decreased from 13.6 to 10.0 hours lost/month and absolute presenteeism scores improved from 67.0 to 77.1. Patients receiving hydrocodone ER showed early numeric improvements in functioning that continued throughout this 12-month study. © 2016 World Institute of Pain.

  13. Extending the life of thermal power plants components by using the triad: checking - diagnosis - restoring; Extinderea duratei de viata a componentelor termoenergetice utilizand Triada: expertiza - diagnoza - remediere

    Energy Technology Data Exchange (ETDEWEB)

    Lupescue, L.; Nicolescu, N.; Delamarian, C.

    2004-12-01

    The current state of thermal power plants components requires a clear cut definition of how to apply the concept of 'Assessing the state and lifetime' to them. The application of the concept of prolonging the life of thermal power plants components represents a practical alternative to the activity of preventive maintenance, by using 'the component oriented maintenance'. A feasibility study gives results that are a covering prediction for the level of technical risk characterizing the operation of technological equipment. There are many methods of analysing the dangers and assessing the risk, as two basic types can be established: a deductive one, in which the final event is presupposed and the events that might cause this final event are searched, and an inductive one, in which the failure of a component is presupposed, and the analysis is to identify the events that led to failure. In compliance with the worldwide trends the authors of the present paper make efforts to apply the methods specific of the probability analyses, efficiently and harmoniously supplementing the concerns and results of the activities based on deterministic methods and models. 13 refs., 1 fig.

  14. Calculation of the hydraulic characteristics of the protective coating used in trenchless technologies for the construction and renovation of pipelines to extend their service life

    Directory of Open Access Journals (Sweden)

    Orlov Vladimir

    2017-01-01

    Full Text Available The lifetime of the pipeline, which undergoes trenchless repair by pulling and then fixing various types of internal protective coatings inside, is determined by the strength characteristics of the two-layer structure “old pipeline + internal protective coating”. Hydraulic parameters of internal protective coatings, such as surface roughness and degree of hydrophobicity (water repellency, can play a role in prolonging the life of the repaired pipeline. With a high degree of hydrophobicity of the protective coating, the contact of the transported liquid with the walls of the pipeline during its operation in the non-pressure regime decreases, which leads to a decrease in the negative impact on the walls, in particular, their attrition, interaction with the specific structure of the coating material, which in turn reduces the energy costs when transporting water. Given article deals with a mathematical description of the interaction of the surface structure (with its inherent wetting ability and the transported liquid in a mini-stream created on an inclined open chute imitating the inner surface of a pressureless pipeline. The theoretical positions and methodology for calculating the degree of hydrophobicity are based on research conducted on the basis of frontal and coaxial (along the flow digital photo and video. T

  15. Preliminary research concerning the use of electron accelerators to improve the conservability and to extend the shelf-life of fruits and vegetables

    International Nuclear Information System (INIS)

    Minea, R.

    1996-01-01

    The potential of ionizing radiation treatment for food preservation, shelf-life extension, control of microbial load and reduction of pathogenic microorganism was demonstrated. The irradiations were performed under normal conditions on the Institute of Physics and Technology for Radiation Device's linear electron accelerator, which has the following parameters: 5 μA mean beam current, 6 MeV electron mean energy, pulse period 3.5 μs and dose rates between 100-1500 Gy/min. This research project was aimed at assuring the consumer's acceptance for radiation-treated food and to obtain a significant reduction of food losses. We also propose a promising solution for the radiation processing of some bulk food products at the place of storage, consisting of a mobile electron accelerator. The main characteristics of the mobile electron accelerator are: electron energy 3 to 5 MeV, maximum beam power 5 kW, vertical electron beam; irradiation is possible both with electron beams and with bremsstrahlung. The results of our preliminary research lead to the conclusion that electron-beam irradiation and the use of electron accelerators is a promising solution for food preservation and food safety. Interesting future applications are outlined. (orig.)

  16. Nonthermal physical technologies to decontaminate and extend the shelf-life of fruits and vegetables: Trends aiming at quality and safety.

    Science.gov (United States)

    Pinela, José; Ferreira, Isabel C F R

    2017-07-03

    Minimally processed fruits and vegetables are one of the major growing sectors in food industry. This growing demand for healthy and convenient foods with fresh-like properties is accompanied by concerns surrounding efficacy of the available sanitizing methods to appropriately deal with food-borne diseases. In fact, chemical sanitizers do not provide an efficient microbial reduction, besides being perceived negatively by the consumers, dangerous for human health, and harmful to the environment, and the conventional thermal treatments may negatively affect physical, nutritional, or bioactive properties of these perishable foods. For these reasons, the industry is investigating alternative nonthermal physical technologies, namely innovative packaging systems, ionizing and ultraviolet radiation, pulsed light, high-power ultrasound, cold plasma, high hydrostatic pressure, and dense phase carbon dioxide, as well as possible combinations between them or with other preservation factors (hurdles). This review discusses the potential of these novel or emerging technologies for decontamination and shelf-life extension of fresh and minimally processed fruits and vegetables. Advantages, limitations, and challenges related to its use in this sector are also highlighted.

  17. Extending over time

    DEFF Research Database (Denmark)

    Christensen, Tanya Karoli; Jensen, Torben Juel; Christensen, Marie Herget

    Studies of general extenders (GEs), such as Eng. and stuff like that, or something, typically find that it is a feature of youth speech, sometimes correlated with sex and class (e.g. Dubois 1992, Stubbe and Holmes 1995, Cheshire 2007, Tagliamonte and Denis 2010, Pichler and Levey 2011), but only...... including pronoun headed phrases, e.g. og (alt) det der ‘and (all) that there’, and clausal variants, e.g. og jeg ved ikke hvad ‘and I don’t know what’. The results indicate that Danish GEs in general are already gram-maticalized to a large extent. Regarding social factors, our data support the general...... finding that GEs are more frequent in youth speech. Adolescents have the highest relative frequency of GEs, and speakers tend to decrease their GE use during their life span, whilst participating in community changes regarding the use of the different GE types. Furthermore, the results suggest...

  18. Hosed vs. unhosed: interruptions of the Atlantic Meridional Overturning Circulation in a global coupled model, with and without freshwater forcing

    Science.gov (United States)

    Brown, Nicolas; Galbraith, Eric D.

    2016-08-01

    It is well known that glacial periods were punctuated by abrupt climate changes, with large impacts on air temperature, precipitation, and ocean circulation across the globe. However, the long-held idea that freshwater forcing, caused by massive iceberg discharges, was the driving force behind these changes has been questioned in recent years. This throws into doubt the abundant literature on modelling abrupt climate change through "hosing" experiments, whereby the Atlantic Meridional Overturning Circulation (AMOC) is interrupted by an injection of freshwater to the North Atlantic: if some, or all, abrupt climate change was not driven by freshwater input, could its character have been very different than the typical hosed experiments? Here, we describe spontaneous, unhosed oscillations in AMOC strength that occur in a global coupled ocean-atmosphere model when integrated under a particular background climate state. We compare these unhosed oscillations to hosed oscillations under a range of background climate states in order to examine how the global imprint of AMOC variations depends on whether or not they result from external freshwater input. Our comparison includes surface air temperature, precipitation, dissolved oxygen concentrations in the intermediate-depth ocean, and marine export production. The results show that the background climate state has a significant impact on the character of the freshwater-forced AMOC interruptions in this model, with particularly marked variations in tropical precipitation and in the North Pacific circulation. Despite these differences, the first-order patterns of response to AMOC interruptions are quite consistent among all simulations, implying that the ocean-sea ice-atmosphere dynamics associated with an AMOC weakening dominate the global response, regardless of whether or not freshwater input is the cause. Nonetheless, freshwater addition leads to a more complete shutdown of the AMOC than occurs in the unhosed oscillations

  19. [Effects of irrigation with different length micro-sprinkling hoses on soil water distribution, water consumption characteristics of winter wheat, and its grain yield].

    Science.gov (United States)

    Man, Jian-guo; Wang, Dong; Yu, Zhen-wen; Zhang, Yong-li; Shi, Yu

    2013-08-01

    Taking the high-yielding winter wheat variety Jimai 22 as test material, a field experiment was conducted in 2010-2012 to study the effects of irrigation with different length micro-sprinkling hoses on the soil water distribution in winter wheat growth period and the water consumption characteristics and grain yield of winter wheat. Three micro-sprinkling hose lengths were designed, i. e., 40 m (T40), 60 m (T60) and 80 m (T80). Under the micro-sprinkling irrigation at jointing and anthesis stages, the uniformity of the horizontal distribution of irrigation water in soil increased significantly with the decrease of hose length from 80 to 40 m. When irrigated at jointing stage, the water content of 0-200 cm soil layer in each space of wheat rows had no significant difference within the 0-40 m distanced from the border initial in treatments T40 and T60. When measured at the 38-40 m, 58-60 m, and 78-80 m distanced from the border initial in treatment T80 at jointing and anthesis stages, the water content in 0-200 cm soil layer had the same change pattern, i. e., decreased with the increasing distance from micro-sprinkling hose. The water consumption amounts in 40-60 cm soil layer from jointing to anthesis stages and in 20-80 cm soil layer from anthesis to maturing stages were higher in treatment T40 than in treatments T60 and T80. However, the soil water consumption amount, irrigation amount at anthesis stage, total irrigation amount, and total water consumption amount were significantly lower in treatment T40 than in treatments T60 and T80. The grain yield, yield water use efficiency increased with the hose length decreased from 80 to 40 m, but the flow decreased. Therefore, the effective irrigation area per unit time decreased with the same irrigation amounts. Considering the grain yield, water use efficiency, and the flow through micro-sprinkling hose, 40 and 60 m were considered to be the appropriate micro-sprinkling hose lengths under this experimental condition.

  20. Extended Shelf Life of Precooked Meals

    Science.gov (United States)

    1974-06-01

    Introduction Background Microbiological aspects Public Health aspects Spoilage Food acceptance Experience of others Nacka system Extensions of the...portions of food , and 50,000 bacteri - ological tests products have been entirely satisfactory. According to the Swedish National Veterinary Board...M.F. Gunderson i960. Role of psychrophllic bacteria in frozen food spoilage . Food Tech. 14, U13J+15. 10. Ingraham,J.L. and J.L. Stokes 1959

  1. Extending the Short Shelf Life of Knowledge.

    Science.gov (United States)

    Meister, Jeanne C.

    1998-01-01

    A corporate university is an educational institution run by a company that functions as the umbrella for a firm's total education requirements. Such institutions often use innovations such as satellite-based and Web-based learning. Training professionals take on new roles such as technology specialists, alliance managers, and account managers.…

  2. Silicone chain extender

    DEFF Research Database (Denmark)

    2015-01-01

    The present invention relates to a silicone chain extender, more particularly a chain extender for silicone polymers and copolymers, to a chain extended silicone polymer or copolymer and to a functionalized chain extended silicone polymer or copolymer, to a method for the preparation thereof...

  3. Extended likelihood inference in reliability

    International Nuclear Information System (INIS)

    Martz, H.F. Jr.; Beckman, R.J.; Waller, R.A.

    1978-10-01

    Extended likelihood methods of inference are developed in which subjective information in the form of a prior distribution is combined with sampling results by means of an extended likelihood function. The extended likelihood function is standardized for use in obtaining extended likelihood intervals. Extended likelihood intervals are derived for the mean of a normal distribution with known variance, the failure-rate of an exponential distribution, and the parameter of a binomial distribution. Extended second-order likelihood methods are developed and used to solve several prediction problems associated with the exponential and binomial distributions. In particular, such quantities as the next failure-time, the number of failures in a given time period, and the time required to observe a given number of failures are predicted for the exponential model with a gamma prior distribution on the failure-rate. In addition, six types of life testing experiments are considered. For the binomial model with a beta prior distribution on the probability of nonsurvival, methods are obtained for predicting the number of nonsurvivors in a given sample size and for predicting the required sample size for observing a specified number of nonsurvivors. Examples illustrate each of the methods developed. Finally, comparisons are made with Bayesian intervals in those cases where these are known to exist

  4. Extended Enterprise performance Management

    NARCIS (Netherlands)

    Bobbink, Maria Lammerdina; Hartmann, Andreas

    2014-01-01

    The allegiance of partnering organisations and their employees to an Extended Enterprise performance is its proverbial sword of Damocles. Literature on Extended Enterprises focuses on collaboration, inter-organizational integration and learning to avoid diminishing or missing allegiance becoming an

  5. Syndrome of extended shadow

    International Nuclear Information System (INIS)

    Ginzburg, M.A.

    1987-01-01

    Syndrome of extended shadow is characterized by large (more than one lobe) or total shadow of the lung area. A detailed roentgenological characteristic and intrasyndrome differential diagnosis of extended shadows is given. Ethiology, pathogenesis and pathomorphology as well as clinical picture and methods of investigation of extended shadows are discussed

  6. Perspectives on extended Deterrence

    International Nuclear Information System (INIS)

    Tertrais, Bruno; Yost, David S.; Bunn, Elaine; Lee, Seok-soo; Levite, Ariel e.; Russell, James A.; Hokayem, Emile; Kibaroglu, Mustafa; Schulte, Paul; Thraenert, Oliver; Kulesa, Lukasz

    2010-05-01

    In November 2009, the Foundation for Strategic Research (Fondation pour la recherche strategique, FRS) convened a workshop on 'The Future of extended Deterrence', which included the participation of some of the best experts of this topic, from the United States, Europe, the Middle East and East Asia, as well as French and NATO officials. This document brings together the papers prepared for this seminar. Several of them were updated after the publication in April 2010 of the US Nuclear Posture Review. The seminar was organized with the support of the French Atomic energy Commission (Commissariat a l'energie atomique - CEA). Content: 1 - The future of extended deterrence: a brainstorming paper (Bruno Tertrais); 2 - US extended deterrence in NATO and North-East Asia (David S. Yost); 3 - The future of US extended deterrence (Elaine Bunn); 4 - The future of extended deterrence: a South Korean perspective (Seok-soo Lee); 5 - Reflections on extended deterrence in the Middle East (Ariel e. Levite); 6 - extended deterrence, security guarantees and nuclear weapons: US strategic and policy conundrums in the Gulf (James A. Russell); 7 - extended deterrence in the Gulf: a bridge too far? (Emile Hokayem); 8 - The future of extended deterrence: the case of Turkey (Mustafa Kibaroglu); 9 - The future of extended deterrence: a UK view (Paul Schulte); 10 - NATO and extended deterrence (Oliver Thraenert); 11 - extended deterrence and assurance in Central Europe (Lukasz Kulesa)

  7. Gamma radiation applied to extend the shelf-life of lamb meat vacuum packed and stored under refrigeration; Radiacao gama aplicada para estender a vida util da carne de cordeiro embalada a vacuo e armazenada sob refrigeracao

    Energy Technology Data Exchange (ETDEWEB)

    Fregonesi, Raul Pereira

    2013-07-01

    days for pH and color b * (yellow), which declined and increased, respectively, over this period. In the sensory acceptance test, the samples did not differ (p> 0,05) in any of the evaluated attributes. Thus, it was concluded that gamma irradiation in the lamb loins was effective in decreasing the proliferation of microorganisms without damaging its physical and chemical characteristics. At the end of the experiment, it was possible to say that the 3.0 kGy dose was indicated because could extend the shelf life of 14 to 56 days of loin of lamb irradiated and stored at 1 °C . (author)

  8. Extending life, enhancing life: a national research agenda on aging

    National Research Council Canada - National Science Library

    Lonergan, Edmund T

    1991-01-01

    ... Division of Health Promotion and Disease Prevention INSTITUTE OF MEDICINE NATIONAL ACADEMY PRESS Washington, D.C. 1991 i Copyrightthe cannot be not from book, paper however, version for formatting, original authoritative the typesetting-specific the as from created publication files XML from other this and of recomposed styl...

  9. Revestimento ativo de amido na conservação pós-colheita de pera Williams minimamente processada Starch-based edible coating on extending shelf life of fresh-cut pear

    Directory of Open Access Journals (Sweden)

    Diego Alvarenga Botrel

    2010-08-01

    Full Text Available A pera é uma das frutas de clima temperado mais consumidas no Brasil, no entanto sua conservação é limitada devido ao seu escurecimento quando sofre danos ou tratamentos físicos. Os revestimentos comestíveis interagem favoravelmente com o alimento, aumentando sua vida de prateleira. Este trabalho objetivou avaliar a ação de revestimento de amido adicionado de lactato de cálcio e L-cisteína na inibição do escurecimento enzimático, na redução do crescimento de psicrotrófilos e enterobactérias e na manutenção da textura. As peras fatiadas foram cobertas com revestimentos comestíveis à base de amido incorporados com cisteína e lactato de cálcio, exceto o controle - sem revestimento (C. Os tratamentos foram: apenas revestimento (T1; 2,0% lactato de cálcio e 1,0% L-cisteína (T2 e 2,0% lactato de cálcio e 1,5% L-cisteína (T3. As amostragens foram feitas nos tempos zero, dois, quatro e seis dias. As amostras foram mantidas sob refrigeração (7°C±2°C. As peras submetidas aos tratamentos T2 e T3 apresentaram-se significativamente mais firmes (PPear is one of the most consumed temperate fruits in Brazil; however their conservation is limited due to browning when it suffers injuries or physical treatments. The edibles coating interact with the food positively extending its shelf life. This research aimed to evaluate the action of starch edible coating incorporated with calcium lactate and L-cysteine on enzymatic browning inhibition, on psychrotrophs and enterobacteriaceae growing reduction and on firmness maintenance. The sliced pears were coated with starch edible coating incorporated with L-cysteine and calcium lactate, except control, without coating (C. The treatment were: only coating (T1; 2,0% calcium lactate and 1,0% L-cysteine (T2; 2,0% calcium lactate and 1,5% L-cysteine (T3. The samples were taken at 0, 2, 4 and 6 days. Pears were keeped under refrigeration (7°C±2°C. Pears submitted to treatments T2 and T3 show

  10. Extended icosahedral structures

    CERN Document Server

    Jaric, Marko V

    1989-01-01

    Extended Icosahedral Structures discusses the concepts about crystal structures with extended icosahedral symmetry. This book is organized into six chapters that focus on actual modeling of extended icosahedral crystal structures. This text first presents a tiling approach to the modeling of icosahedral quasiperiodic crystals. It then describes the models for icosahedral alloys based on random connections between icosahedral units, with particular emphasis on diffraction properties. Other chapters examine the glassy structures with only icosahedral orientational order and the extent of tra

  11. Extending Database Integration Technology

    National Research Council Canada - National Science Library

    Buneman, Peter

    1999-01-01

    Formal approaches to the semantics of databases and database languages can have immediate and practical consequences in extending database integration technologies to include a vastly greater range...

  12. Does switching from oral extended-release methylphenidate to the methylphenidate transdermal system affect health-related quality-of-life and medication satisfaction for children with attention-deficit/hyperactivity disorder?

    Directory of Open Access Journals (Sweden)

    Landgraf Jeanne M

    2009-12-01

    Full Text Available Abstract Background To evaluate health-related quality of life (HRQL and medication satisfaction after switching from a stable dose of oral extended-release methylphenidate (ER-MPH to methylphenidate transdermal system (MTS via a dose-transition schedule in children with attention-deficit/hyperactivity disorder (ADHD. Methods In a 4-week, multisite, open-label study, 171 children (164 in the intent-to-treat [ITT] population aged 6-12 years diagnosed with ADHD abruptly switched from a stable dose of oral ER-MPH to MTS nominal dosages of 10, 15, 20, and 30 mg using a predefined dose-transition schedule. Subjects remained on the scheduled dose for the first week, after which the dose was then titrated to an optimal effect. The ADHD Impact Module-Children (AIM-C, a disease-specific validated HRQL survey instrument measuring child and family impact, was used to assess the impact of ADHD symptoms on the lives of children and their families at baseline and study endpoint. Satisfaction with MTS use was assessed via a Medication Satisfaction Survey (MSS at study endpoint. Both the AIM-C and MSS were completed by a caregiver (parent/legally authorized representative. Tolerability was monitored by spontaneous adverse event (AE reporting. Results AIM-C child and family HRQL mean scores were above the median possible score at baseline and were further improved at endpoint across all MTS doses. Similar improvements were noted for behavior, missed doses, worry, and economic impact AIM-C item scores. Overall, 93.8% of caregivers indicated a high level of satisfaction with their child's use of the study medication. The majority of treatment-emergent AEs (> 98% were mild to moderate in intensity, and the most commonly reported AEs included headache, decreased appetite, insomnia, and abdominal pain. Seven subjects discontinued the study due to intolerable AEs (n = 3 and application site reactions (n = 4. Conclusion This study demonstrates that MTS, when carefully

  13. Patient-reported health-related quality of life, work productivity, and activity impairment during treatment with ALO-02 (extended-release oxycodone and sequestered naltrexone) for moderate-to-severe chronic low back pain.

    Science.gov (United States)

    Weil, Arnold J; Masters, Elizabeth T; Barsdorf, Alexandra I; Bass, Almasa; Pixton, Glenn; Wilson, Jacquelyn G; Wolfram, Gernot

    2017-10-17

    The efficacy of ALO-02, an abuse-deterrent formulation containing extended-release oxycodone and sequestered naltrexone, in the treatment of chronic low back pain (CLBP) was studied in a 12-week randomized controlled trial. Primary efficacy endpoint results have been published previously (Rauck et al., 2015). The current paper focuses on patient-reported outcomes for health-related quality of life (HRQL), work productivity, and activity impairment that were assessed during this study. This was a double-blind, placebo-controlled, randomized withdrawal study in patients with moderate-to-severe CLBP. After a screening period (≤2 weeks), patients entered an open-label titration period (4-6 weeks). Treatment responders were then randomized to a double-blind placebo-controlled treatment period (12 weeks). HRQL was assessed using changes in the Short Form-36 v2 Health Survey (SF-36v2) and the EuroQol-5 Dimensions Health Questionnaire 3-Level version (EQ-5D-3L). Work productivity and regular activities were evaluated using the Work Productivity and Activity Impairment Questionnaire: Specific Health Problem (WPAI:SHP). A total of 410 patients received ALO-02 during the open-label titration period, of which 280 (intent-to-treat (ITT) population) were treated during the double-blind placebo-controlled treatment period (placebo, n = 134; ALO-02, n = 146). Significant improvement was observed for all SF-36v2 subscales and component scores (p < 0.005) and the EQ-5D-3L summary index and visual analog scale (p < 0.0001) during the titration period. Improvement was also significant (p < 0.0001) for all WPAI:SHP outcomes except 'work time missed due to CLBP' for the titration period. Significant differences favoring ALO-02 compared with placebo were only observed for the SF-36v2 Bodily Pain subscale (p ≤ 0.0232; ITT population) during the double-blind treatment period and the overall study period (screening to the end of the double-blind treatment period). The percentage change

  14. Extended Theories of Gravitation

    Directory of Open Access Journals (Sweden)

    Fatibene Lorenzo

    2013-09-01

    Full Text Available Extended theories of gravitation are naturally singled out by an analysis inspired by the Ehelers-Pirani-Schild framework. In this framework the structure of spacetime is described by a Weyl geometry which is enforced by dynamics. Standard General Relativity is just one possible theory within the class of extended theories of gravitation. Also all Palatini f(R theories are shown to be extended theories of gravitation. This more general setting allows a more general interpretation scheme and more general possible couplings between gravity and matter. The definitions and constructions of extended theories will be reviewed. A general interpretation scheme will be considered for extended theories and some examples will be considered.

  15. Extended family medicine training

    Science.gov (United States)

    Slade, Steve; Ross, Shelley; Lawrence, Kathrine; Archibald, Douglas; Mackay, Maria Palacios; Oandasan, Ivy F.

    2016-01-01

    Abstract Objective To examine trends in family medicine training at a time when substantial pedagogic change is under way, focusing on factors that relate to extended family medicine training. Design Aggregate-level secondary data analysis based on the Canadian Post-MD Education Registry. Setting Canada. Participants All Canadian citizens and permanent residents who were registered in postgraduate family medicine training programs within Canadian faculties of medicine from 1995 to 2013. Main outcome measures Number and proportion of family medicine residents exiting 2-year and extended (third-year and above) family medicine training programs, as well as the types and numbers of extended training programs offered in 2015. Results The proportion of family medicine trainees pursuing extended training almost doubled during the study period, going from 10.9% in 1995 to 21.1% in 2013. Men and Canadian medical graduates were more likely to take extended family medicine training. Among the 5 most recent family medicine exit cohorts (from 2009 to 2013), 25.9% of men completed extended training programs compared with 18.3% of women, and 23.1% of Canadian medical graduates completed extended training compared with 13.6% of international medical graduates. Family medicine programs vary substantially with respect to the proportion of their trainees who undertake extended training, ranging from a low of 12.3% to a high of 35.1% among trainees exiting from 2011 to 2013. Conclusion New initiatives, such as the Triple C Competency-based Curriculum, CanMEDS–Family Medicine, and Certificates of Added Competence, have emerged as part of family medicine education and credentialing. In acknowledgment of the potential effect of these initiatives, it is important that future research examine how pedagogic change and, in particular, extended training shapes the care family physicians offer their patients. As part of that research it will be important to measure the breadth and uptake of

  16. Building Extended Families

    Science.gov (United States)

    McKain, Barbara; McKain, Michael

    1970-01-01

    Discusses need for dissolution of the couple" relationship with substitution of the extended family which would permit each member to maintain individuality and to function on own merit. Suggests group living as preferable alternative. (CJ)

  17. Rational extended thermodynamics

    CERN Document Server

    Müller, Ingo

    1998-01-01

    Ordinary thermodynamics provides reliable results when the thermodynamic fields are smooth, in the sense that there are no steep gradients and no rapid changes. In fluids and gases this is the domain of the equations of Navier-Stokes and Fourier. Extended thermodynamics becomes relevant for rapidly varying and strongly inhomogeneous processes. Thus the propagation of high­ frequency waves, and the shape of shock waves, and the regression of small-scale fluctuation are governed by extended thermodynamics. The field equations of ordinary thermodynamics are parabolic while extended thermodynamics is governed by hyperbolic systems. The main ingredients of extended thermodynamics are • field equations of balance type, • constitutive quantities depending on the present local state and • entropy as a concave function of the state variables. This set of assumptions leads to first order quasi-linear symmetric hyperbolic systems of field equations; it guarantees the well-posedness of initial value problems and f...

  18. Switching from oral risperidone to flexibly dosed oral paliperidone extended-release: core symptoms, satisfaction, and quality of life in patients with stable but symptomatic schizophrenia: the RISPALI study.

    Science.gov (United States)

    Gattaz, Wagner F; Campos, João Alberto de Oliveira; Lacerda, Acioly L T; Henna, Elaine; Ruschel, Sandra Inês; Bressan, Rodrigo A; de Oliveira, Irismar Reis; Rocha, Fábio Lopes; Grabowski, Hamilton M; Sacomani, Ernindo; Louzã, Mario R; Quevedo, João; Elkis, Hélio; Zorzetto Filho, Dirceu; Périco, Cintia de Azevedo-Marques; Lawson, Fábio Lorea; Appolinário, José Carlos

    2014-04-01

    The purpose of this prospective study was to evaluate the effects of switching from oral risperidone to flexibly dosed oral paliperidone extended-release (ER) in Brazilian adults with schizophrenia because of lack of efficacy, intolerability, or nonadherence after a minimum trial of 30 days on adequate (labeled) doses of oral risperidone, according to individual clinical judgment. Subjects with Positive and Negative Syndrome Scale total scores above 78, and/or intolerable adverse effects, with risperidone received open-label paliperidone ER 3 to 12 mg daily for 26 (main phase) to 52 (extension phase) weeks. Clinicaltrials.gov identifier: NCT01010776. The intent-to-treat (efficacy) populations comprised 213 subjects in the main phase and 159 in the extension phase. Of 213 subjects with baseline and post-baseline efficacy data, 154 (72.3%) switched from risperidone to paliperidone ER because of a lack of efficacy and 59 (27.7%) because of tolerability issues, according to individual clinical judgment. Paliperidone ER significantly (p < 0.0500) improved a broad spectrum of efficacy endpoints from baseline, as early as the first post-baseline visit (Visit 2; 4 weeks) and persisting through 26 to 52 weeks. On most efficacy endpoints, function improved from baseline to the first post-baseline visit (week 4) and remained significantly improved compared to baseline at each visit for paliperidone ER treatment, at weeks 8, 13, 26, 39, 26, and 52; data are reported herein mainly for 26 and 52 weeks compared to baseline. Significant improvements from baseline were observed for the Positive and Negative Syndrome Scale total score and subscale scores (each p < 0.0001 at 26 and 52 weeks vs. baseline); and personal and social functioning (p < 0.0001 at 26 and 52 weeks). Paliperidone ER also significantly improved health-related quality of life (Short-Form 36) from baseline, particularly on the Mental Component Summary (p = 0.0011 at 26 weeks and p = 0.0019 at

  19. Extending quantum mechanics entails extending special relativity

    International Nuclear Information System (INIS)

    Aravinda, S; Srikanth, R

    2016-01-01

    The complementarity between signaling and randomness in any communicated resource that can simulate singlet statistics is generalized by relaxing the assumption of free will in the choice of measurement settings. We show how to construct an ontological extension for quantum mechanics (QMs) through the oblivious embedding of a sound simulation protocol in a Newtonian spacetime. Minkowski or other intermediate spacetimes are ruled out as the locus of the embedding by virtue of hidden influence inequalities. The complementarity transferred from a simulation to the extension unifies a number of results about quantum non-locality, and implies that special relativity has a different significance for the ontological model and for the operational theory it reproduces. Only the latter, being experimentally accessible, is required to be Lorentz covariant. There may be certain Lorentz non-covariant elements at the ontological level, but they will be inaccessible at the operational level in a valid extension. Certain arguments against the extendability of QM, due to Conway and Kochen (2009) and Colbeck and Renner (2012), are attributed to their assumption that the spacetime at the ontological level has Minkowski causal structure. (paper)

  20. Test methods for foil and textile fibre hoses for the rehabilitation of gas piplines; Pruefmethoden fuer Folien- und Gewebeschlaeuche zum Sanieren von Gasleitungen

    Energy Technology Data Exchange (ETDEWEB)

    Driesen, H.E. [Karlsruhe Univ. (T.H.) (Germany). DVGW-Forschungsstelle am Engler-Bunte-Institut

    1995-01-01

    The Standard for ``means for the subsequent sealing of joints of gaspipes laid in the ground`` (DIN 30658) required a supplement, after various processes were developed, not only for sealing the leaking sleeve joints, but for cladding long sections of pipe with foil or woven hoses. The functional tests on sealed sleeve joints taken over largely unchanged were supplemented by specific tests of the cladding, which concern the opening of existing house connection and the production of new ones, the bridging of corrosion damage and unused tee-offs, and for woven hoses the behaviour during pipe fractures with the raising of the maximum permitted working pressure from 1 bar in DIN 30658 to 4 bar. There is a report on the results of a research project financed by DVGW for working out test proceedures and requirements. (orig.) [Deutsch] Die Norm ueber ``Mittel zum nachtraeglichen Abdichten von Verbindungen erdverlegter Gasleitungen`` (DIN 30658) bedurfte einer Ergaenzung, nachdem verschiedene Verfahren entwickelt wurden, nicht nur gezielt die undichten Muffenverbindungen abzudichten, sondern laengere Leitungsabschnitte mit Folien- oder Gewebeschlaeuchen auszukleiden. Die im wesentlichen unveraendert uebernommenen Funktionspruefungen an abgedichteten Muffenverbindungen wurden durch spezifische Pruefungen der Auskleidung ergaenzt, die das Oeffnen bestehender und die Erstellung neuer Hausanschluesse, die Ueberbrueckung von Korrosionsschaeden und stillgelegten Abgaengen sowie bei Gewebeschlaeuchen das Verhalten bei Rohrbruechen bei Anhebung des max. zulaessigen Betriebsdruckes von 1 bar in DIN 30658 auf 4 bar betreffen. Ueber die Ergebnisse eines vom DVGW finanzierten Forschungsvorhabens zur Erarbeitung von Pruefverfahren und Anforderungen wird berichtet. (orig.)

  1. Hosing Instability of the Drive Electron Beam in the E157 Plasma-Wakefield Acceleration Experiment at the Stanford Linear Accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Blue, Brent Edward; /SLAC /UCLA

    2005-10-10

    In the plasma-wakefield experiment at SLAC, known as E157, an ultra-relativistic electron beam is used to both excite and witness a plasma wave for advanced accelerator applications. If the beam is tilted, then it will undergo transverse oscillations inside of the plasma. These oscillations can grow exponentially via an instability know as the electron hose instability. The linear theory of electron-hose instability in a uniform ion column predicts that for the parameters of the E157 experiment (beam charge, bunch length, and plasma density) a growth of the centroid offset should occur. Analysis of the E157 data has provided four critical results. The first was that the incoming beam did have a tilt. The tilt was much smaller than the radius and was measured to be 5.3 {micro}m/{delta}{sub z} at the entrance of the plasma (IP1.) The second was the beam centroid oscillates in the ion channel at half the frequency of the beam radius (betatron beam oscillations), and these oscillations can be predicted by the envelope equation. Third, up to the maximum operating plasma density of E157 ({approx}2 x 10{sup 14} cm{sup -3}), no growth of the centroid offset was measured. Finally, time-resolved data of the beam shows that up to this density, no significant growth of the tail of the beam (up to 8ps from the centroid) occurred even though the beam had an initial tilt.

  2. Hosing Instability of the Drive Electron Beam in the E157 Plasma-Wakefield Acceleration Experiment at the Stanford Linear Accelerator

    International Nuclear Information System (INIS)

    Blue, Brent Edward

    2005-01-01

    In the plasma-wakefield experiment at SLAC, known as E157, an ultra-relativistic electron beam is used to both excite and witness a plasma wave for advanced accelerator applications. If the beam is tilted, then it will undergo transverse oscillations inside of the plasma. These oscillations can grow exponentially via an instability know as the electron hose instability. The linear theory of electron-hose instability in a uniform ion column predicts that for the parameters of the E157 experiment (beam charge, bunch length, and plasma density) a growth of the centroid offset should occur. Analysis of the E157 data has provided four critical results. The first was that the incoming beam did have a tilt. The tilt was much smaller than the radius and was measured to be 5.3 (micro)m/(delta) z at the entrance of the plasma (IP1.) The second was the beam centroid oscillates in the ion channel at half the frequency of the beam radius (betatron beam oscillations), and these oscillations can be predicted by the envelope equation. Third, up to the maximum operating plasma density of E157 (∼2 x 10 14 cm -3 ), no growth of the centroid offset was measured. Finally, time-resolved data of the beam shows that up to this density, no significant growth of the tail of the beam (up to 8ps from the centroid) occurred even though the beam had an initial tilt

  3. An Extended Duopoly Game.

    Science.gov (United States)

    Eckalbar, John C.

    2002-01-01

    Illustrates how principles and intermediate microeconomic students can gain an understanding for strategic price setting by playing a relatively large oligopoly game. Explains that the game extends to a continuous price space and outlines appropriate applications. Offers the Mathematica code to instructors so that the assumptions of the game can…

  4. Extending Critical Performativity

    DEFF Research Database (Denmark)

    Spicer, André; Alvesson, Mats; Kärreman, Dan

    2016-01-01

    from an undue focus on intra-academic debates; engage in author-itarian theoretical policing; feign relevance through symbolic radicalism; and repackage common sense. We take these critiques as an opportunity to offer an extended model of critical performativity that involves focusing on issues...

  5. Parameterization of extended systems

    DEFF Research Database (Denmark)

    Niemann, Hans Henrik

    2006-01-01

    The YJBK parameterization (of all stabilizing controllers) is extended to handle systems with additional sensors and/or actuators. It is shown that the closed loop transfer function is still an affine function in the YJBK parameters in the nominal case. Further, some closed-loop stability results...

  6. Poster Session- Extended Abstracts

    Science.gov (United States)

    Jack D. Alexander III; Jean Findley; Brenda K. Kury; Jan L. Beyers; Douglas S. Cram; Terrell T. Baker; Jon C. Boren; Carl Edminster; Sue A. Ferguson; Steven McKay; David Nagel; Trent Piepho; Miriam Rorig; Casey Anderson; Jeanne Hoadley; Paulette L. Ford; Mark C. Andersen; Ed L. Fredrickson; Joe Truett; Gary W. Roemer; Brenda K. Kury; Jennifer Vollmer; Christine L. May; Danny C. Lee; James P. Menakis; Robert E. Keane; Zhi-Liang Zhu; Carol Miller; Brett Davis; Katharine Gray; Ken Mix; William P. Kuvlesky Jr.; D. Lynn Drawe; Marcia G. Narog; Roger D. Ottmar; Robert E. Vihnanek; Clinton S. Wright; Timothy E. Paysen; Burton K. Pendleton; Rosemary L. Pendleton; Carleton S. White; John Rogan; Doug Stow; Janet Franklin; Jennifer Miller; Lisa Levien; Chris Fischer; Emma Underwood; Robert Klinger; Peggy Moore; Clinton S. Wright

    2008-01-01

    Titles found within Poster Session-Extended Abstracts include:Assessment of emergency fire rehabilitation of four fires from the 2000 fire season on the Vale, Oregon, BLM district: review of the density sampling materials and methods: p. 329 Growth of regreen, seeded for erosion control, in the...

  7. Extended Irreversible Thermodynamics

    CERN Document Server

    Jou, David

    2010-01-01

    This is the 4th edition of the highly acclaimed monograph on Extended Irreversible Thermodynamics, a theory that goes beyond the classical theory of irreversible processes. In contrast to the classical approach, the basic variables describing the system are complemented by non-equilibrium quantities. The claims made for extended thermodynamics are confirmed by the kinetic theory of gases and statistical mechanics. The book covers a wide spectrum of applications, and also contains a thorough discussion of the foundations and the scope of the current theories on non-equilibrium thermodynamics. For this new edition, the authors critically revised existing material while taking into account the most recent developments in fast moving fields such as heat transport in micro- and nanosystems or fast solidification fronts in materials sciences. Several fundamental chapters have been revisited emphasizing physics and applications over mathematical derivations. Also, fundamental questions on the definition of non-equil...

  8. The dialogically extended mind

    DEFF Research Database (Denmark)

    Fusaroli, Riccardo; Gangopadhyay, Nivedita; Tylén, Kristian

    2014-01-01

    , we argue that language enhances our cognitive capabilities in a much more radical way: The skilful engagement of public material symbols facilitates evolutionarily unprecedented modes of collective perception, action and reasoning (interpersonal synergies) creating dialogically extended minds. We...... relate our approach to other ideas about collective minds and review a number of empirical studies to identify the mechanisms enabling the constitution of interpersonal cognitive systems....

  9. Extended quantum mechanics

    International Nuclear Information System (INIS)

    Pavel Bona

    2000-01-01

    The work can be considered as an essay on mathematical and conceptual structure of nonrelativistic quantum mechanics which is related here to some other (more general, but also to more special and 'approximative') theories. Quantum mechanics is here primarily reformulated in an equivalent form of a Poisson system on the phase space consisting of density matrices, where the 'observables', as well as 'symmetry generators' are represented by a specific type of real valued (densely defined) functions, namely the usual quantum expectations of corresponding selfjoint operators. It is shown in this paper that inclusion of additional ('nonlinear') symmetry generators (i. e. 'Hamiltonians') into this reformulation of (linear) quantum mechanics leads to a considerable extension of the theory: two kinds of quantum 'mixed states' should be distinguished, and operator - valued functions of density matrices should be used in the role of 'nonlinear observables'. A general framework for physical theories is obtained in this way: By different choices of the sets of 'nonlinear observables' we obtain, as special cases, e.g. classical mechanics on homogeneous spaces of kinematical symmetry groups, standard (linear) quantum mechanics, or nonlinear extensions of quantum mechanics; also various 'quasiclassical approximations' to quantum mechanics are all sub theories of the presented extension of quantum mechanics - a version of the extended quantum mechanics. A general interpretation scheme of extended quantum mechanics extending the usual statistical interpretation of quantum mechanics is also proposed. Eventually, extended quantum mechanics is shown to be (included into) a C * -algebraic (hence linear) quantum theory. Mathematical formulation of these theories is presented. The presentation includes an analysis of problems connected with differentiation on infinite-dimensional manifolds, as well as a solution of some problems connected with the work with only densely defined unbounded

  10. Use of Optical Oxygen Sensors in Non-Destructively Determining the Levels of Oxygen Present in Combined Vacuum and Modified Atmosphere Packaged Pre-Cooked Convenience-Style Foods and the Use of Ethanol Emitters to Extend Product Shelf-Life

    Science.gov (United States)

    Hempel, Andreas W.; Papkovsky, Dmitri B.; Kerry, Joseph P.

    2013-01-01

    O2 sensors were used to non-destructively monitor O2 levels in commercially packed pre-cooked, convenience modified atmosphere packaging (MAP) foods. A substantial level of O2 (>15%) was present in packs resulting in a shorter than expected shelf-life, where the primary spoilage mechanism was found to be mould. Various combinations of vacuum (0–0.6 MPa) and gas flush (0.02–0.03 MPa) (30% CO2/70% N2) settings were assessed as treatments that result in the desired shelf-life (28 days). This was achieved using the combined treatment of vacuum 0.35 MPa and gas flush 0.02 MPa which resulted in a reduction of 6%–9% O2 in all three samples (battered sausages (BS), bacon slices (BA), and meat and potato pies (PP)). Reduced O2 levels reflect the microbial quality of products, which has been successfully reduced. Duplicate samples of all product packs were produced using ethanol emitters (EE) to see if shelf-life could be further extended. Results showed a further improvement in shelf-life to 35 days. Sensory analysis showed that ethanol flavour and aroma was not perceived by panellists in two of the three products assessed. This study demonstrates how smart packaging technologies, both intelligent and active, can be used to assist in the modification of conventional packaging systems in order to enhance product quality and safety and through the extension of product shelf-life. PMID:28239134

  11. Extended Testability Analysis Tool

    Science.gov (United States)

    Melcher, Kevin; Maul, William A.; Fulton, Christopher

    2012-01-01

    The Extended Testability Analysis (ETA) Tool is a software application that supports fault management (FM) by performing testability analyses on the fault propagation model of a given system. Fault management includes the prevention of faults through robust design margins and quality assurance methods, or the mitigation of system failures. Fault management requires an understanding of the system design and operation, potential failure mechanisms within the system, and the propagation of those potential failures through the system. The purpose of the ETA Tool software is to process the testability analysis results from a commercial software program called TEAMS Designer in order to provide a detailed set of diagnostic assessment reports. The ETA Tool is a command-line process with several user-selectable report output options. The ETA Tool also extends the COTS testability analysis and enables variation studies with sensor sensitivity impacts on system diagnostics and component isolation using a single testability output. The ETA Tool can also provide extended analyses from a single set of testability output files. The following analysis reports are available to the user: (1) the Detectability Report provides a breakdown of how each tested failure mode was detected, (2) the Test Utilization Report identifies all the failure modes that each test detects, (3) the Failure Mode Isolation Report demonstrates the system s ability to discriminate between failure modes, (4) the Component Isolation Report demonstrates the system s ability to discriminate between failure modes relative to the components containing the failure modes, (5) the Sensor Sensor Sensitivity Analysis Report shows the diagnostic impact due to loss of sensor information, and (6) the Effect Mapping Report identifies failure modes that result in specified system-level effects.

  12. Classical extended superconformal symmetries

    International Nuclear Information System (INIS)

    Viswanathan, R.R.

    1990-10-01

    Super-covariant differential operators are defined in two dimensions which map supersymmetry doublets to other doublets. The possibility of constructing a closed algebra among the fields appearing in such operators is explored. Such an algebra exists for Grassmann-odd differential operators. A representation for these operators in terms of free-field doublets is constructed. An explicit closed algebra involving fields of spin 2 and 5/2, in addition to the stress tensor and the supersymmetry generator, is constructed from such a free-field representation as an example of a non-linear extended superconformal algebra. (author). 9 refs

  13. Lunar Prospector Extended Mission

    Science.gov (United States)

    Folta, David; Beckman, Mark; Lozier, David; Galal, Ken

    1999-01-01

    The National Aeronautics and Space Administration (NASA) selected Lunar Prospector (LP) as one of the discovery missions to conduct solar system exploration science investigations. The mission is NASA's first lunar voyage to investigate key science objectives since Apollo and was launched in January 1998. In keeping with discovery program requirements to reduce total mission cost and utilize new technology, Lunar Prospector's mission design and control focused on the use of innovative and proven trajectory analysis programs. As part of this effort, the Ames Research Center and the Goddard Space Flight Center have become partners in the Lunar Prospector trajectory team to provide the trajectory analysis, maneuver planning, orbit determination support, and product generation. At the end of 1998, Lunar Prospector completed its one-year primary mission at 100 km altitude above the lunar surface. On December 19, 1998, Lunar Prospector entered the extended mission phase. Initially the mission orbit was lowered from 100 km to a mean altitude of 40 km. The altitude of Lunar Prospector varied between 25 and 55 km above the mean lunar geode due to lunar potential effects. After one month, the lunar potential model was updated based upon the new tracking data at 40 km. On January 29, 1999, the altitude was lowered again to a mean altitude of 30 km. This altitude varies between 12 and 48 km above the mean lunar geode. Since the minimum altitude is very close to the mean geode, various approaches were employed to get accurate lunar surface elevation including Clementine altimetry and line of sight analysis. Based upon the best available terrain maps, Lunar Prospector will reach altitudes of 8 km above lunar mountains in the southern polar and far side regions. This extended mission phase of six months will enable LP to obtain science data up to 3 orders of magnitude better than at the mission orbit. This paper details the trajectory design and orbit determination planning and

  14. Extended biorthogonal matrix polynomials

    Directory of Open Access Journals (Sweden)

    Ayman Shehata

    2017-01-01

    Full Text Available The pair of biorthogonal matrix polynomials for commutative matrices were first introduced by Varma and Tasdelen in [22]. The main aim of this paper is to extend the properties of the pair of biorthogonal matrix polynomials of Varma and Tasdelen and certain generating matrix functions, finite series, some matrix recurrence relations, several important properties of matrix differential recurrence relations, biorthogonality relations and matrix differential equation for the pair of biorthogonal matrix polynomials J(A,B n (x, k and K(A,B n (x, k are discussed. For the matrix polynomials J(A,B n (x, k, various families of bilinear and bilateral generating matrix functions are constructed in the sequel.

  15. Extending rational maps

    Science.gov (United States)

    Martin, Gaven J.

    We investigate when a rational endomorphism of the Riemann sphere overline{C} extends to a mapping of the upper half-space {H3 which is rational with respect to some measurable conformal structure. Such an extension has the property that it and all its iterates have uniformly bounded distortion. Such maps are called uniformly quasiregular. We show that, in the space of rational mappings of degree d , such an extension is possible in the structurally stable component where there is a single (attracting) component of the Fatou set and the Julia set is a Cantor set. We show that generally outside of this set no such extension is possible. In particular, polynomials can never admit such an extension.

  16. Extending juvenility in grasses

    Energy Technology Data Exchange (ETDEWEB)

    Kaeppler, Shawn; de Leon Gatti, Natalia; Foerster, Jillian

    2017-04-11

    The present invention relates to compositions and methods for modulating the juvenile to adult developmental growth transition in plants, such as grasses (e.g. maize). In particular, the invention provides methods for enhancing agronomic properties in plants by modulating expression of GRMZM2G362718, GRMZM2G096016, or homologs thereof. Modulation of expression of one or more additional genes which affect juvenile to adult developmental growth transition such as Glossy15 or Cg1, in conjunction with such modulation of expression is also contemplated. Nucleic acid constructs for down-regulation of GRMZM2G362718 and/or GRMZM2G096016 are also contemplated, as are transgenic plants and products produced there from, that demonstrate altered, such as extended juvenile growth, and display associated phenotypes such as enhanced yield, improved digestibility, and increased disease resistance. Plants described herein may be used, for example, as improved forage or feed crops or in biofuel production.

  17. Extended Poisson Exponential Distribution

    Directory of Open Access Journals (Sweden)

    Anum Fatima

    2015-09-01

    Full Text Available A new mixture of Modified Exponential (ME and Poisson distribution has been introduced in this paper. Taking the Maximum of Modified Exponential random variable when the sample size follows a zero truncated Poisson distribution we have derived the new distribution, named as Extended Poisson Exponential distribution. This distribution possesses increasing and decreasing failure rates. The Poisson-Exponential, Modified Exponential and Exponential distributions are special cases of this distribution. We have also investigated some mathematical properties of the distribution along with Information entropies and Order statistics of the distribution. The estimation of parameters has been obtained using the Maximum Likelihood Estimation procedure. Finally we have illustrated a real data application of our distribution.

  18. Extended lactation in dairy cows

    DEFF Research Database (Denmark)

    Sorensen, Annette; Muir, D. Donald; Knight, Christopher Harold

    2008-01-01

    Twelve spring-calving and twelve winter-calving cows were managed for extended lactation cycles of 18-months duration, with the former group then completing a second extended lactation. Half of the cows were fed according to standard management practice for the herd; the other half received suppl...... interventions, the results lend support to the economic arguments in favour of extended lactation cycles. The likely welfare benefits of extended lactation are also discussed....

  19. Development of underwater robot for taking off marine life

    International Nuclear Information System (INIS)

    Hirai, Harumi; Wakamatsu, Kazuhiko; Ueda, Ryohei; Edahiro, Kyosuke; Hayashi, Shunichi.

    1983-01-01

    Fouling by marine life growths in the cooling water system at seaside power generating stations is a major problem in the maintenance of a safe and efficient operation. Ingress of released growths into the condensers and coolers often jeopardizes their tube life and performance by clogging and/or tube corrosion. Many stations are obliged to remove periodically the growths manually after drying-out the system or by divers at considerable expenditure in time and money. A new remote-controlled underwater robot is developed for brushing marine life off cooling water intake channels of thermal and nuclear power generation plants. This robot consists of an underwater working unit, a power supply system, hydraulic hose take-up unit and controlling equipment. The full hydraulically powered robot, which can be used for both open and closed conduits, permits cleaning under water intake servicing condition. It drastically reduces both time and cost. (author)

  20. Use of Optical Oxygen Sensors in Non-Destructively Determining the Levels of Oxygen Present in Combined Vacuum and Modified Atmosphere Packaged Pre-Cooked Convenience-Style Foods and the Use of Ethanol Emitters to Extend Product Shelf-Life

    Directory of Open Access Journals (Sweden)

    Andreas W. Hempel

    2013-11-01

    Full Text Available O2 sensors were used to non-destructively monitor O2 levels in commercially packed pre-cooked, convenience modified atmosphere packaging (MAP foods. A substantial level of O2 (>15% was present in packs resulting in a shorter than expected shelf-life, where the primary spoilage mechanism was found to be mould. Various combinations of vacuum (0–0.6 MPa and gas flush (0.02–0.03 MPa (30% CO2/70% N2 settings were assessed as treatments that result in the desired shelf-life (28 days. This was achieved using the combined treatment of vacuum 0.35 MPa and gas flush 0.02 MPa which resulted in a reduction of 6%–9% O2 in all three samples (battered sausages (BS, bacon slices (BA, and meat and potato pies (PP. Reduced O2 levels reflect the microbial quality of products, which has been successfully reduced. Duplicate samples of all product packs were produced using ethanol emitters (EE to see if shelf-life could be further extended. Results showed a further improvement in shelf-life to 35 days. Sensory analysis showed that ethanol flavour and aroma was not perceived by panellists in two of the three products assessed. This study demonstrates how smart packaging technologies, both intelligent and active, can be used to assist in the modification of conventional packaging systems in order to enhance product quality and safety and through the extension of product shelf-life.

  1. Irreducibility conditions for extended superfields

    International Nuclear Information System (INIS)

    Sokatchev, E.

    1981-05-01

    The irreducible supermultiplets contained in an extended superfield are presented as sets of covariant derivatives of the superfield. Differential irreducibility constraints are easily obtained from this decomposition. (author)

  2. On core stability and extendability

    OpenAIRE

    Shellshear, Evan

    2007-01-01

    This paper investigates conditions under which the core of a TU cooperative game is stable. In particular the author extends the idea of extendability to find new conditions under which the core is stable. It is also shown that these new conditions are not necessary for core stability.

  3. Extending cosmology: the metric approach

    OpenAIRE

    Mendoza, S.

    2012-01-01

    Comment: 2012, Extending Cosmology: The Metric Approach, Open Questions in Cosmology; Review article for an Intech "Open questions in cosmology" book chapter (19 pages, 3 figures). Available from: http://www.intechopen.com/books/open-questions-in-cosmology/extending-cosmology-the-metric-approach

  4. Extended Active Disturbance Rejection Controller

    Science.gov (United States)

    Gao, Zhiqiang (Inventor); Tian, Gang (Inventor)

    2016-01-01

    Multiple designs, systems, methods and processes for controlling a system or plant using an extended active disturbance rejection control (ADRC) based controller are presented. The extended ADRC controller accepts sensor information from the plant. The sensor information is used in conjunction with an extended state observer in combination with a predictor that estimates and predicts the current state of the plant and a co-joined estimate of the system disturbances and system dynamics. The extended state observer estimates and predictions are used in conjunction with a control law that generates an input to the system based in part on the extended state observer estimates and predictions as well as a desired trajectory for the plant to follow.

  5. Scale-invariant extended inflation

    International Nuclear Information System (INIS)

    Holman, R.; Kolb, E.W.; Vadas, S.L.; Wang, Y.

    1991-01-01

    We propose a model of extended inflation which makes use of the nonlinear realization of scale invariance involving the dilaton coupled to an inflaton field whose potential admits a metastable ground state. The resulting theory resembles the Jordan-Brans-Dicke version of extended inflation. However, quantum effects, in the form of the conformal anomaly, generate a mass for the dilaton, thus allowing our model to evade the problems of the original version of extended inflation. We show that extended inflation can occur for a wide range of inflaton potentials with no fine-tuning of dimensionless parameters required. Furthermore, we also find that it is quite natural for the extended-inflation period to be followed by an epoch of slow-rollover inflation as the dilaton settles down to the minimum of its induced potential

  6. Resistor Extends Life Of Battery In Clocked CMOS Circuit

    Science.gov (United States)

    Wells, George H., Jr.

    1991-01-01

    Addition of fixed resistor between battery and clocked complementary metal oxide/semiconductor (CMOS) circuit reduces current drawn from battery. Basic idea to minimize current drawn from battery by operating CMOS circuit at lowest possible current consistent with use of simple, fixed off-the-shelf components. Prolongs lives of batteries in such low-power CMOS circuits as watches and calculators.

  7. Extending the storage life of garlic by gamma-irradiation

    International Nuclear Information System (INIS)

    Curzio, O.A.; Croci, C.A.; Quaranta, H.O.

    1983-01-01

    The effect of gamma irradiation (0.03kGy) on garlic bulbs from local cultivars was studied. The treatment proved to be effective in reducing weight loss and spoilage percentage of the bulbs. After 10 months of storage the weight loss was found to be reduced by 37% in irradiated garlic. Irradiation reduced sprouting of the fresh bulbs but did not affect the rotting process. (author)

  8. Extended asymptotic functions - some examples

    International Nuclear Information System (INIS)

    Todorov, T.D.

    1981-01-01

    Several examples of extended asymptotic functions of two variables are given. This type of asymptotic functions has been introduced as an extension of continuous ordinary functions. The presented examples are realizations of some Schwartz distributions delta(x), THETA(x), P(1/xsup(n)) and can be multiplied in the class of the asymptotic functions as opposed to the theory of Schwartz distributions. The examples illustrate the method of construction of extended asymptotic functions similar to the distributions. The set formed by the extended asymptotic functions is also considered. It is shown, that this set is not closed with respect to addition and multiplication

  9. Cosmological dynamics of extended chameleons

    Energy Technology Data Exchange (ETDEWEB)

    Tamanini, Nicola [Institut de Physique Théorique, CEA-Saclay, CNRS UMR 3681, Université Paris-Saclay, F-91191 Gif-sur-Yvette (France); Wright, Matthew, E-mail: nicola.tamanini@cea.fr, E-mail: matthew.wright.13@ucl.ac.uk [Department of Mathematics, University College London, Gower Street, London, WC1E 6BT (United Kingdom)

    2016-04-01

    We investigate the cosmological dynamics of the recently proposed extended chameleon models at both background and linear perturbation levels. Dynamical systems techniques are employed to fully characterize the evolution of the universe at the largest distances, while structure formation is analysed at sub-horizon scales within the quasi-static approximation. The late time dynamical transition from dark matter to dark energy domination can be well described by almost all extended chameleon models considered, with no deviations from ΛCDM results at both background and perturbation levels. The results obtained in this work confirm the cosmological viability of extended chameleons as alternative dark energy models.

  10. Cosmological dynamics of extended chameleons

    International Nuclear Information System (INIS)

    Tamanini, Nicola; Wright, Matthew

    2016-01-01

    We investigate the cosmological dynamics of the recently proposed extended chameleon models at both background and linear perturbation levels. Dynamical systems techniques are employed to fully characterize the evolution of the universe at the largest distances, while structure formation is analysed at sub-horizon scales within the quasi-static approximation. The late time dynamical transition from dark matter to dark energy domination can be well described by almost all extended chameleon models considered, with no deviations from ΛCDM results at both background and perturbation levels. The results obtained in this work confirm the cosmological viability of extended chameleons as alternative dark energy models.

  11. Quasi-extended asymptotic functions

    International Nuclear Information System (INIS)

    Todorov, T.D.

    1979-01-01

    The class F of ''quasi-extended asymptotic functions'' is introduced. It contains all extended asymptotic functions as well as some new asymptotic functions very similar to the Schwartz distributions. On the other hand, every two quasiextended asymptotic functions can be multiplied as opposed to the Schwartz distributions; in particular, the square delta 2 of an asymptotic function delta similar to Dirac's delta-function, is constructed as an example

  12. Topological defects in extended inflation

    International Nuclear Information System (INIS)

    Copeland, E.J.; Kolb, E.W.; Chicago Univ., IL; Liddle, A.R.

    1990-04-01

    We consider the production of topological defects, especially cosmic strings, in extended inflation models. In extended inflation, the Universe passes through a first-order phase transition via bubble percolation, which naturally allows defects to form at the end of inflation. The correlation length, which determines the number density of the defects, is related to the mean size of bubbles when they collide. This mechanism allows a natural combination of inflation and large-scale structure via cosmic strings. 18 refs

  13. Some problems with extended inflation

    International Nuclear Information System (INIS)

    Weinberg, E.J.

    1989-01-01

    The recently proposed extended inflation scenario is examined. Upper bounds on the Brans-Dicke parameter ω are obtained by requiring that the recovery from the supercooled regime be such that the presently observed Universe could have emerged. These bounds are well below the present-day experimental limits, implying that one must use models which have a potential to fix the present value of the Brans-Dicke-like scalar field. The implications for extended inflation in such models are discussed

  14. Topological defects in extended inflation

    International Nuclear Information System (INIS)

    Copeland, E.J.; Kolb, E.W.; Liddle, A.R.

    1990-01-01

    We consider the production of topological defects, especially cosmic strings, in extended-inflation models. In extended inflation, the Universe passes through a first-order phase transition via bubble percolation, which naturally allows defects to form at the end of inflation. The correlation length, which determines the number density of the defects, is related to the mean size of the bubbles when they collide. This mechanism allows a natural combination of inflation and large-scale structure via cosmic strings

  15. Extender for securing a closure

    Science.gov (United States)

    Thomas, II, Patrick A.

    2012-10-02

    An apparatus for securing a closure such as door or a window that opens and closes by movement relative to a fixed structure such as a wall or a floor. Many embodiments provide a device for relocating a padlock from its normal location where it secures a fastener (such as a hasp) to a location for the padlock that is more accessible for locking and unlocking the padlock. Typically an extender is provided, where the extender has a hook at a first end that is disposed through the eye of the staple of the hasp, and at an opposing second end the extender has an annulus, such as a hole in the extender or a loop or ring affixed to the extender. The shackle of the padlock may be disposed through the annulus and may be disposed through the eye of a second staple to secure the door or window in a closed or open position. Some embodiments employ a rigid sheath to enclose at least a portion of the extender. Typically the rigid sheath has an open state where the hook is exposed outside the sheath and a closed state where the hook is disposed within the sheath.

  16. Review of extended producer responsibility: A case study approach.

    Science.gov (United States)

    Gupt, Yamini; Sahay, Samraj

    2015-07-01

    Principles of extended producer responsibility have been the core of most of the recent policies and legislation dealing with the end-of-life management of recyclable goods. This article makes an exploratory review of 27 cases of extended producer responsibility from developed and developing economies with and without informal recycling, to ascertain the most important aspect of extended producer responsibility. A comparative analysis of the cases with respect to role of stakeholders in the upstream and downstream stages of the extended producer responsibility has been carried out. Further, the study uses exploratory factor analysis to determine the important aspects of the extended producer responsibility in practice using 13 variables identified from the review. Findings of the comparative analysis reveal that financial responsibility of the producers and separate collecting and recycling agencies contributed significantly to the success of the extended producer responsibility-based environmental policies. Regulatory provisions, take-back responsibility and financial flow come out to be the three most important aspects of the extended producer responsibility. Presence of informal sector had a negative impact on the regulatory provisions. The outcomes of this study could serve as a guideline for designing of effective extended producer responsibility-based policies. © The Author(s) 2015.

  17. Extended Year, Extended Contracts: Increasing Teacher Salary Options.

    Science.gov (United States)

    Gandara, Patricia

    1992-01-01

    Reports on an attempt to raise teacher salaries through an extended contract made possible through year-round school schedules. Teacher satisfaction with the 1987 experiment in three California schools (the Orchard Plan) has been high. Elements that have contributed to job satisfaction are discussed. (SLD)

  18. Extended cognition in science communication.

    Science.gov (United States)

    Ludwig, David

    2014-11-01

    The aim of this article is to propose a methodological externalism that takes knowledge about science to be partly constituted by the environment. My starting point is the debate about extended cognition in contemporary philosophy and cognitive science. Externalists claim that human cognition extends beyond the brain and can be partly constituted by external devices. First, I show that most studies of public knowledge about science are based on an internalist framework that excludes the environment we usually utilize to make sense of science and does not allow the possibility of extended knowledge. In a second step, I argue that science communication studies should adopt a methodological externalism and accept that knowledge about science can be partly realized by external information resources such as Wikipedia. © The Author(s) 2013.

  19. Decomposing change in life expectancy

    DEFF Research Database (Denmark)

    Vaupel, James W.; Canudas Romo, Vladimir

    2003-01-01

    We extend Nathan Keyfitz's research on continuous change in life expectancy over time by presenting and proving a new formula for decomposing such change. The formula separates change in life expectancy over time into two terms. The first term captures the general effect of reduction in death rates...... at all ages, and the second term captures the effect of heterogeneity in the pace of improvement in mortality at different ages. We extend the formula to decompose change in life expectancy into age-specific and cause-specific components, and apply the methods to analyze changes in life expectancy...

  20. Extended Storage of Pathogen-Reduced Platelet Concentrates (PRECON)

    Science.gov (United States)

    2016-10-01

    proposes to determine the efficacy of using a pathogen inactivation technique (Mirasol) coupled with a platelet additive solution (PAS) to extend the life...participation. • Subjects must have good veins for apheresis platelet collection and drawing blood samples. • Subjects of child-bearing potential (either male or

  1. Remaining life assessment and plant life extension in high temperature components of power and petrochemical plant

    International Nuclear Information System (INIS)

    Fleming, A.

    2003-01-01

    This paper explains the reasons why plant life can so easily be extended beyond the original design life. It details the means by which plant life extension is normally achieved, a structured plan for achieving such plant life extension at reasonable cost and some of the key techniques used in assessing the remaining life and discusses the simple repair options available. (author)

  2. Shear rheology of extended nanoparticles

    Science.gov (United States)

    Petersen, Matt K.; Lane, J. Matthew D.; Grest, Gary S.

    2010-07-01

    Nonequilibrium molecular-dynamics simulations are presented for the shear rheology of suspensions of extended “jack”-shaped nanoparticles in an explicit solvent. The shear viscosity is measured for two jack-shaped nanoparticle suspensions for volume fractions from 0.01 to 0.15 and compared to spherical nanoparticles of the same mass. Large differences, in some cases, orders of magnitude, are observed for both the equilibrium viscosity and diffusion constant as the shape of the nanoparticle is varied. The source of enhanced viscosity is the very large effective volume swept out by these extended nanoparticles which allows them to become highly entangled even at low volume fraction.

  3. Effective operators and extended symmetry

    CERN Document Server

    Frère, J M; Moreno, J M; Orloff, J

    1994-01-01

    In this note we expand on our previous study of the implications of LEP1 results for future colliders. We extend the effective operator-based analysis of De R\\'ujula et al. to a larger symmetry group, and show at which cost their expectations can be relaxed. Of particular interest to experiment is a rephrasing of our previous results in terms of the Renard et al. parametrization for the gauge boson self-couplings (slightly extended to include $\\delta g_{\\gamma}$). We suggest the use of a ($\\delta g_{\\gamma}$, $\\delta g_{Z}$) plot to confront the expectations of various models.

  4. Adjustable extender for instrument module

    International Nuclear Information System (INIS)

    Sevec, J.B.; Stein, A.D.

    1975-01-01

    A blank extender module used to mount an instrument module in front of its console for repair or test purposes has been equipped with a rotatable mount and means for locking the mount at various angles of rotation for easy accessibility. The rotatable mount includes a horizontal conduit supported by bearings within the blank module. The conduit is spring-biased in a retracted position within the blank module and in this position a small gear mounted on the conduit periphery is locked by a fixed pawl. The conduit and instrument mount can be pulled into an extended position with the gear clearing the pawl to permit rotation and adjustment of the instrument

  5. Exclusion Bounds for Extended Anyons

    Science.gov (United States)

    Larson, Simon; Lundholm, Douglas

    2018-01-01

    We introduce a rigorous approach to the many-body spectral theory of extended anyons, that is quantum particles confined to two dimensions that interact via attached magnetic fluxes of finite extent. Our main results are many-body magnetic Hardy inequalities and local exclusion principles for these particles, leading to estimates for the ground-state energy of the anyon gas over the full range of the parameters. This brings out further non-trivial aspects in the dependence on the anyonic statistics parameter, and also gives improvements in the ideal (non-extended) case.

  6. Applying and extending Oracle Spatial

    CERN Document Server

    Simon Gerard Greener, Siva Ravada

    2013-01-01

    This book is an advanced practical guide to applying and extending Oracle Spatial.This book is for existing users of Oracle and Oracle Spatial who have, at a minimum, basic operational experience of using Oracle or an equivalent database. Advanced skills are not required.

  7. Ghosts in extended quasidilaton theories

    Science.gov (United States)

    Golovnev, Alexey; Trukhin, Aleksandr

    2017-11-01

    We report on our independent investigations of the puzzle of cosmological perturbations in extended quasidilaton. We confirm the claims of presence of the Boulware-Deser ghost. We use both the language of cosmological perturbations with broken diffeomorphisms and the Stückelberg approach.

  8. Extended memory management under RTOS

    Science.gov (United States)

    Plummer, M.

    1981-01-01

    A technique for extended memory management in ROLM 1666 computers using FORTRAN is presented. A general software system is described for which the technique can be ideally applied. The memory manager interface with the system is described. The protocols by which the manager is invoked are presented, as well as the methods used by the manager.

  9. Extended duration orbiter (EDO) insignia

    Science.gov (United States)

    1990-01-01

    Extended duration orbiter (EDO) insignia incorporates a space shuttle orbiter with payload bay doors (PLBDs) open and a spacelab module inside. Trailing the orbiter are the initials EDO. The EDO-modified Columbia, Orbiter Vehicle (OV) 102, will be flown for the first EDO mission, STS-50.

  10. Extended Duration Orbiter Medical Project

    Science.gov (United States)

    Leach, C. S.; Pool, S. L.; Sawin, C. F.; Nicogossian, A. E.

    1990-01-01

    The Extended Duration Orbiter (EDO) program addresses a need for more time to perform experiments and other tasks during Space Shuttle missions. As a part of this program, the Extended Duration Orbiter Medical Project (EDOMP) has been instituted to obtain information about physiologic effects of extending mission duration and the effectiveness of countermeasures against factors that might compromise crew health, safety, or performance on extended-duration missions. Only those investigations that address and characterize operational problems, develop countermeasures, or evaluate the effectiveness of countermeasures will be pursued. The EDOMP investigations will include flight-associated Detailed Supplementary Objectives as well as ground-based studies simulating the influence of microgravity. Investigator teams have been formed in the following areas: biomedical physiology, cardiovascular and fluid/electrolyte physiology, environmental health, muscle and exercise physiology, and neurophysiology. Major operational questions must be answered in each of these areas, and investigations have been designed to answer them. The EDO program will proceed only after countermeasures have been shown to be effective in preventing or mitigating the adverse changes they have been designed to attenuate. The program is underway and will continue on each Shuttle flight as the manifest builds toward a 16-day orbital flight.

  11. Extended unemployment and UI benefits

    OpenAIRE

    Robert G. Valletta; Katherine Kuang

    2010-01-01

    During the current labor market downturn, unemployment duration has reached levels well above its previous highs. Analysis of unemployment data suggests that extended unemployment insurance benefits have not been important factors in the increase in the duration of unemployment or in the elevated unemployment rate.

  12. Engage, Enhance, and Extend Learning!

    Science.gov (United States)

    Keren-Kolb, Liz

    2013-01-01

    Educators often say that technology is more than a gimmick or add-on, and that it should engage, enhance, or extend learning in ways that traditional tools do not. Yet they seldom stop to define these terms, and they can be confusing, especially for teachers and preservice teachers. Recently, while collaborating on an English language arts and…

  13. Creating a Generic Extended Enterprise Management Model using GERAM

    DEFF Research Database (Denmark)

    Larsen, Lars Bjørn; Kaas-Pedersen, Carsten; Vesterager, Johan

    1998-01-01

    The two main themes of the Globeman21 (Global Manufacturing in the 21st century) project are product life cycle management and extended enterprise management. This article focus on the later of these subjects and an illustration of the concept is given together with a discussion of the concept...... of virtual enterprises. Through the introduction of GERAM (Generalised Enterprise Reference Architecture and Methodology) an initial version of a basic framework for extended enterprise management is introduced. This basic framework is the first step towards the creation of a generic extended enterprise...... management model. By working with GERAM in relation to extended enterprise management it has been found that it provides a useful background for organising knowledge, experience and the activities within the project...

  14. Extending Teach and Repeat to Pivoting Wheelchairs

    Directory of Open Access Journals (Sweden)

    Guillermo Del Castillo

    2003-02-01

    Full Text Available The paper extends the teach-and-repeat paradigm that has been successful for the control of holonomic robots to nonholonomic wheelchairs which may undergo pivoting action over the course of their taught movement. Due to the nonholonomic nature of the vehicle kinematics, estimation is required -- in the example given herein, based upon video detection of wall-mounted cues -- both in the teaching and the tracking events. In order to accommodate motion that approaches pivoting action as well as motion that approaches straight-line action, the estimation equations of the Extended Kalman Filter and the control equations are formulated using two different definitions of a nontemporal independent variable. The paper motivates the need for pivoting action in real-life settings by reporting extensively on the abilities and limitations of estimation-based teach-and-repeat action where pivoting and near-pivoting action is disallowed. Following formulation of the equations in the near-pivot mode, the paper reports upon experiments where taught trajectories which entail a seamless mix of near-straight and near-pivot action are tracked.

  15. Departies: conceptualizing extended youth parties

    DEFF Research Database (Denmark)

    Fjær, Eivind Grip; Tutenges, Sébastien

    2017-01-01

    Every year, millions of young people travel away from home to party for days or weeks on end in permissive environments, such as music festivals, dance parties, and nightlife resorts. The studies that have been conducted on these extended youth parties have focused primarily on specific risk......-taking behaviors, such as drug use and violence. Here, we scrutinize the research on extended youth parties to identify general changes that young people undergo at these events. We call these celebrations departies, because they center on the organization and facilitation of momentary departures from...... immoral; (4) stylistically, by altering their stylistic expressions through dress, demeanor, and consumption; and (5) experientially, because the parties generate mood and mind alterations. These are overlapping and intertwined elements, the combination of which amounts to a distinct type of youth party...

  16. Non-invasive extending prosthesis

    OpenAIRE

    Meswania, Jayantilal Mohanlal

    2006-01-01

    Most sarcomas of the bone occur in patients of a relatively young age including skeletally immature patients. Approximately 50 child sarcomas are treated with limb salvage surgery per year in the United Kingdom. These children need an extendible implant that can be lengthened periodically to keep pace with the growth in the opposite limb. Surgically, invasive devices have been used for the past thirty years with intrinsic problems of infection and long-term recurrent trauma to the patient. To...

  17. Black holes from extended inflation

    International Nuclear Information System (INIS)

    Hsu, S.D.H.; Lawrence Berkeley Lab., CA

    1990-01-01

    It is argued that models of extended inflation, in which modified Einstein gravity allows a graceful exit from the false vacuum, lead to copious production of black holes. The critical temperature of the inflationary phase transition must be >10 8 GeV in order to avoid severe cosmological problems in a universe dominated by black holes. We speculate on the possibility that the interiors of false vacuum regions evolve into baby universes. (orig.)

  18. Locating and extending livelihoods research

    DEFF Research Database (Denmark)

    Prowse, Martin

    2008-01-01

    Much poverty and development research is not explicit about its methodology or philosophical foundations. Based on the extended case method of Burawoy and the epistemological standpoint of critical realism, this paper discusses a methodological approach for reflexive inductive livelihoods researc...... that overcomes the unproductive social science dualism of positivism and social constructivism. The approach is linked to a conceptual framework and a menu of research methods that can be sequenced and iterated in light of research questions....

  19. Extended producer responsibility in oligopoly

    OpenAIRE

    Hiroaki Ino

    2007-01-01

    I investigate the optimal environmental tax under a policy based on extended producer responsibility (EPR) in oligopoly markets. I introduce the recycling market and explicitly consider how these policies affect the incentive for recycling. I derive the optimal tax rule, which depends on the weighted sum of the markup in the product market and the markdown in the recycling market. In contrast to the existing works that emphasize that the optimal tax rate is lower than the marginal external da...

  20. Extended inflation with induced gravity

    International Nuclear Information System (INIS)

    Accetta, F.S.; Trester, J.J.; Department of Physics, Yale University, New Haven, Connecticut 06520)

    1989-01-01

    We consider a recently proposed extended model of inflation which improves upon the original old inflation scenario by achieving a graceful exit from the false-vacuum phase. In this paper extended inflation is generalized to include a potential V(phi) for the Brans-Dicke-type field phi. We find that whereas a graceful exit can still be had, the inclusion of a potential places constraints on the percolation time scale for exiting the inflationary phase. Additional constraints on V(phi) and the false-vacuum energy density rho /sub F/ from density and gravitational-wave perturbations are discussed. For initially small values of phi the false vacuum undergoes power-law inflation, while for initially large values of phi the expansion is exponential. Within true-vacuum regions slow-rolling inflation can occur. As a result, this model generically leads to multiple episodes of inflation. We discuss the significance these multiple episodes of inflation may have on the formation of large-scale structure and the production of voids

  1. Creating robust vocabulary frequently asked questions and extended examples

    CERN Document Server

    Beck, Isabel L

    2008-01-01

    Bringing Words to Life has enlivened the classrooms of hundreds of thousands of teachers. Responding to readers' success stories, practical questions, and requests for extended examples, this ideal volume builds on the groundbreaking work of Bringing Words to Life. The authors present additional tools, tips, and detailed explanations of such questions as which words to teach, when and how to teach them, and how to adapt instruction for English language learners. They provide specific instructional sequences, including assessments, for grades K-2, 3-5, 6-8, and 9-12, as well as interactive less

  2. The extended palliative phase of dementia - An integrative literature review.

    Science.gov (United States)

    Hanson, Elizabeth; Hellström, Amanda; Sandvide, Åsa; Jackson, Graham A; MacRae, Rhoda; Waugh, Anna; Abreu, Wilson; Tolson, Debbie

    2016-07-26

    This article presents an integrative literature review of the experience of dementia care associated with the extended palliative phase of dementia. The aim was to highlight how dementia is defined in the literature and describe what is known about the symptomatology and management of advanced dementia regarding the needs and preferences of the person with dementia and their family carer/s. There was no consistent definition of advanced dementia. The extended palliative phase was generally synonymous with end-of-life care. Advanced care planning is purported to enable professionals to work together with people with dementia and their families. A lack of understanding of palliative care among frontline practitioners was related to a dearth of educational opportunities in advanced dementia care. There are few robust concepts and theories that embrace living the best life possible during the later stages of dementia. These findings informed our subsequent work around the concept, 'Dementia Palliare'. © The Author(s) 2016.

  3. Topics in Extended Dynamical Systems

    Science.gov (United States)

    Bhagavatula, Ravi S.

    This thesis consists of three chapters. Each chapter is self-contained and is devoted to the investigation of a particular topic in extended dynamical systems. In the first chapter, an approach based on Langevin equations is implemented to understand the non-Gaussian nature of the probability distribution function (PDF) of local diffusive variables in extended dynamical systems, e.g., a passive scalar advected by turbulent velocity fluctuations. Two mechanisms are proposed for the origin of non-Gaussian tails: One relies on the nature of temporal correlations of the fluctuations that couple additively to the diffusive field, leading to exponential and stretched exponential tails in the PDF; the other depends on multiplicative coupling between the diffusive field and the fluctuations, producing algebraic tails in the PDF. The mechanisms are illustrated using models for a passive scalar and also a current driven Josephson junction array. This study indicates that shapes of local PDFs in turbulent states are non-universal and crucially depend on local couplings and time scales. The second chapter establishes the existence of a class of locally conserving chaotic (deterministic) systems that exhibit Generic Scale Invariance--algebraic decay of spatial and temporal correlations without tuning parameters. This study also reveals the similarity between noise and chaos in extended systems as far as long-wavelength and long -time behavior is concerned. Specifically, a two dimensional coupled-map lattice model with a conserved density is numerically shown to exhibit, in agreement with heuristic arguments, algebraic decay of spatio-temporal correlations in chaotic states with simple predictable exponents. The third chapter investigates scaling behavior of earthquakes in seismic zone models in which an earthquake is modeled by a quasi-static description that ignores short -time dynamics during an earthquake. The models incorporate the essential feature of long-ranged stress

  4. Extended uncertainty from first principles

    Energy Technology Data Exchange (ETDEWEB)

    Costa Filho, Raimundo N., E-mail: rai@fisica.ufc.br [Departamento de Física, Universidade Federal do Ceará, Caixa Postal 6030, Campus do Pici, 60455-760 Fortaleza, Ceará (Brazil); Braga, João P.M., E-mail: philipe@fisica.ufc.br [Instituto de Ciências Exatas e da Natureza-ICEN, Universidade da Integração Internacional da Lusofonia Afro-Brasileira-UNILAB, Campus dos Palmares, 62785-000 Acarape, Ceará (Brazil); Lira, Jorge H.S., E-mail: jorge.lira@mat.ufc.br [Departamento de Matemática, Universidade Federal do Ceará, Caixa Postal 6030, Campus do Pici, 60455-760 Fortaleza, Ceará (Brazil); Andrade, José S., E-mail: soares@fisica.ufc.br [Departamento de Física, Universidade Federal do Ceará, Caixa Postal 6030, Campus do Pici, 60455-760 Fortaleza, Ceará (Brazil)

    2016-04-10

    A translation operator acting in a space with a diagonal metric is introduced to describe the motion of a particle in a quantum system. We show that the momentum operator and, as a consequence, the uncertainty relation now depend on the metric. It is also shown that, for any metric expanded up to second order, this formalism naturally leads to an extended uncertainty principle (EUP) with a minimum momentum dispersion. The Ehrenfest theorem is modified to include an additional term related to a tidal force arriving from the space curvature introduced by the metric. For one-dimensional systems, we show how to map a harmonic potential to an effective potential in Euclidean space using different metrics.

  5. Learning Extended Finite State Machines

    Science.gov (United States)

    Cassel, Sofia; Howar, Falk; Jonsson, Bengt; Steffen, Bernhard

    2014-01-01

    We present an active learning algorithm for inferring extended finite state machines (EFSM)s, combining data flow and control behavior. Key to our learning technique is a novel learning model based on so-called tree queries. The learning algorithm uses the tree queries to infer symbolic data constraints on parameters, e.g., sequence numbers, time stamps, identifiers, or even simple arithmetic. We describe sufficient conditions for the properties that the symbolic constraints provided by a tree query in general must have to be usable in our learning model. We have evaluated our algorithm in a black-box scenario, where tree queries are realized through (black-box) testing. Our case studies include connection establishment in TCP and a priority queue from the Java Class Library.

  6. Harmonic superspaces of extended supersymmetry

    International Nuclear Information System (INIS)

    Ivanov, E.; Kalitzin, S.; Nguyen Ai Viet; Ogievetsky, V.

    1984-01-01

    The main technical apparatus of the harmonic superspace approach to extended SUSY, the calculus of harmonic variables on homogeneous spaces of the SUSY automorphism groups, is presented in detail for N=2, 3, 4. The basic harmonics for the coset manifolds G/H with G=SU(2), H=U(1); G=SU(3), H=SU(2)xU(1) and H=U(1)xU(1); G=SU(4), H=SU(3)xU(1), H=SU(2)xSU(2)xU(1), H=SU(2)xU(1)xU(1) and H=U(1)xU(1)xU(1); G=USp(2), H=SU(2)xSU(2), H=SU(2)xU(1) and H=U(1)xU(1) are tabulated a number of useful relations among them

  7. Extended uncertainty from first principles

    International Nuclear Information System (INIS)

    Costa Filho, Raimundo N.; Braga, João P.M.; Lira, Jorge H.S.; Andrade, José S.

    2016-01-01

    A translation operator acting in a space with a diagonal metric is introduced to describe the motion of a particle in a quantum system. We show that the momentum operator and, as a consequence, the uncertainty relation now depend on the metric. It is also shown that, for any metric expanded up to second order, this formalism naturally leads to an extended uncertainty principle (EUP) with a minimum momentum dispersion. The Ehrenfest theorem is modified to include an additional term related to a tidal force arriving from the space curvature introduced by the metric. For one-dimensional systems, we show how to map a harmonic potential to an effective potential in Euclidean space using different metrics.

  8. Hamiltonian dynamics of extended objects

    International Nuclear Information System (INIS)

    Capovilla, R; Guven, J; Rojas, E

    2004-01-01

    We consider relativistic extended objects described by a reparametrization-invariant local action that depends on the extrinsic curvature of the worldvolume swept out by the object as it evolves. We provide a Hamiltonian formulation of the dynamics of such higher derivative models which is motivated by the ADM formulation of general relativity. The canonical momenta are identified by looking at boundary behaviour under small deformations of the action; the relationship between the momentum conjugate to the embedding functions and the conserved momentum density is established. The canonical Hamiltonian is constructed explicitly; the constraints on the phase space, both primary and secondary, are identified and the role they play in the theory is described. The multipliers implementing the primary constraints are identified in terms of the ADM lapse and shift variables and Hamilton's equations are shown to be consistent with the Euler-Lagrange equations

  9. Hamiltonian dynamics of extended objects

    Energy Technology Data Exchange (ETDEWEB)

    Capovilla, R [Departamento de FIsica, Centro de Investigacion y de Estudios Avanzados del IPN, Apdo Postal 14-740, 07000 Mexico, DF (Mexico); Guven, J [School of Theoretical Physics, Dublin Institute for Advanced Studies, 10 Burlington Road, Dublin 4 (Ireland); Rojas, E [Instituto de Ciencias Nucleares, Universidad Nacional Autonoma de Mexico, Apdo Postal 70-543, 04510 Mexico, DF (Mexico)

    2004-12-07

    We consider relativistic extended objects described by a reparametrization-invariant local action that depends on the extrinsic curvature of the worldvolume swept out by the object as it evolves. We provide a Hamiltonian formulation of the dynamics of such higher derivative models which is motivated by the ADM formulation of general relativity. The canonical momenta are identified by looking at boundary behaviour under small deformations of the action; the relationship between the momentum conjugate to the embedding functions and the conserved momentum density is established. The canonical Hamiltonian is constructed explicitly; the constraints on the phase space, both primary and secondary, are identified and the role they play in the theory is described. The multipliers implementing the primary constraints are identified in terms of the ADM lapse and shift variables and Hamilton's equations are shown to be consistent with the Euler-Lagrange equations.

  10. Application of low-dose gamma irradiation to extend the shelf life of minimally processed Red Beet (Beta vulgaris sp. vulgaris L.), cv. Early Wonder; Aplicacao de baixas doses de radiacao gama para extensao da vida util de beterraba vermelha (Beta vulgaris ssp. vulgaris L.), cv. Early Wonder, minimamente processada

    Energy Technology Data Exchange (ETDEWEB)

    Hernandez, Nilber Kenup

    2006-07-01

    detected independently of the dose. In addition, physicochemical analyses investigated the evolution of pH; total acidity; total soluble solids and ascorbic acid throughout storage. Samples from experiment 2 were also subjected to sensory analyses for overall appearance and aroma at 4 different post-irradiation times. The results indicated that the samples irradiated with 1.0 and 1.5 kGy remained good for consumption for 20 days. Therefore it can be concluded that the application of those doses extended the shelf life of the samples without harming their nutritional and sensory quality. Finally, the results indicate that the dose of 1.0 kGy is the most appropriate for the conservation of red beet among those tested. (author)

  11. The Extended Virgo Cluster Catalog

    Science.gov (United States)

    Rey, Soo-Chang

    2015-08-01

    We present a new catalog of galaxies in the wider region of the Virgo cluster, based on the Sloan Digital Sky Survey (SDSS) Data Release 7. The Extended Virgo Cluster Catalog (EVCC) covers an area of 725 deg2 or 60.1 Mpc2. It is 5.2 times larger than the footprint of the classical Virgo Cluster Catalog (VCC) and reaches out to 3.5 times the virial radius of the Virgo cluster. We selected 1324 spectroscopically targeted galaxies with radial velocities less than 3000 km s-1. In addition, 265 galaxies that have been overlooked in the SDSS spectroscopic survey but have available redshifts in the NASA Extragalactic Database are also included. Our selection process secured a total of 1589 galaxies, 676 of which are not included in the VCC. The certain and possible cluster members are defined by means of redshift comparison with a cluster infall model. We employed two independent and complementary galaxy classification schemes: the traditional morphological classification based on the visual inspection of optical images and a characterization of galaxies from their spectroscopic features. SDSS u, g, r, i, and z passband photometry of all EVCC galaxies was performed using Source Extractor. We compare the EVCC galaxies with the VCC in terms of morphology, spatial distribution, and luminosity function. The EVCC defines a comprehensive galaxy sample covering a wider range in galaxy density that is significantly different from the inner region of the Virgo cluster. It will be the foundation for forthcoming galaxy evolution studies in the extended Virgo cluster region, complementing ongoing and planned Virgo cluster surveys at various wavelengths.

  12. Oral hydromorphone extended-release.

    Science.gov (United States)

    Guay, David R P

    2010-12-01

    To review the chemistry, pharmacodynamics, pharmacokinetics, efficacy, tolerability, dosing, and role of the Osmotic-controlled Release Oral delivery System (OROS) hydromorphone extended-release (ER) tablets. A MEDLINE/PUBMED search (1986-August 2010) was conducted to identify studies in the English language, with additional references being obtained from their bibliographies. All studies of hydromorphone ER were reviewed. This is the second long-acting hydromorphone formulation to receive approval by the Food and Drug Administration (a twice-daily formulation was approved in September 2004, but was subsequently withdrawn in July 2005). Hydromorphone is a semi-synthetic mu-opioid receptor agonist structurally similar to morphine, hydrocodone, and oxymorphone. OROS ER technology allows once-daily dosing. Clinical trials have focused on the convertibility of (an) other opioid(s) to hydromorphone ER in chronic malignant and nonmalignant pain. This product displays the expected opioid side effects, being comparable to oxycodone controlled-release. Coadministration with ethanol does not produce the degree of "dose-dumping" seen with the former hydromorphone twice-daily product or oxymorphone ER. Hydromorphone ER is indicated for the management of moderate-to-severe pain in opioidtolerant patients requiring continuous, around-the-clock opioid analgesia for an extended period of time. Dosage adjustment is recommended in patients with moderate hepatic impairment (Child-Pugh class B) and moderate renal impairment (creatinine clearance of 30-60 mL/min). Hydromorphone ER is the newest oral opioid to enter a crowded marketplace now totaling 15 different Schedule 2 opioids (including tapentadol), and tramadol, available in oral, parenteral, rectal, transdermal, transmucosal, and intranasal formulations. It does not appear to have any unique assets or liabilities and should be considered as one of many oral opioids available for the management of persistent pain of moderate

  13. THE EXTENDED VIRGO CLUSTER CATALOG

    International Nuclear Information System (INIS)

    Kim, Suk; Rey, Soo-Chang; Lee, Youngdae; Chung, Jiwon; Pak, Mina; Yi, Wonhyeong; Lee, Woong; Jerjen, Helmut; Lisker, Thorsten; Sung, Eon-Chang

    2014-01-01

    We present a new catalog of galaxies in the wider region of the Virgo cluster, based on the Sloan Digital Sky Survey (SDSS) Data Release 7. The Extended Virgo Cluster Catalog (EVCC) covers an area of 725 deg 2 or 60.1 Mpc 2 . It is 5.2 times larger than the footprint of the classical Virgo Cluster Catalog (VCC) and reaches out to 3.5 times the virial radius of the Virgo cluster. We selected 1324 spectroscopically targeted galaxies with radial velocities less than 3000 km s –1 . In addition, 265 galaxies that have been overlooked in the SDSS spectroscopic survey but have available redshifts in the NASA Extragalactic Database are also included. Our selection process secured a total of 1589 galaxies, 676 of which are not included in the VCC. The certain and possible cluster members are defined by means of redshift comparison with a cluster infall model. We employed two independent and complementary galaxy classification schemes: the traditional morphological classification based on the visual inspection of optical images and a characterization of galaxies from their spectroscopic features. SDSS u, g, r, i, and z passband photometry of all EVCC galaxies was performed using Source Extractor. We compare the EVCC galaxies with the VCC in terms of morphology, spatial distribution, and luminosity function. The EVCC defines a comprehensive galaxy sample covering a wider range in galaxy density that is significantly different from the inner region of the Virgo cluster. It will be the foundation for forthcoming galaxy evolution studies in the extended Virgo cluster region, complementing ongoing and planned Virgo cluster surveys at various wavelengths

  14. Extended Power Up-rates

    International Nuclear Information System (INIS)

    Jon Ball

    2006-01-01

    Full text of publication follows: Nuclear energy is a reliable and cost-competitive global source of power. With rising oil and gas prices, nuclear continues to provide economic and environmental benefits. Extended Power Up-rate (EPU) provides a means for existing nuclear assets to generate increased power and substantially reduce electrical generation costs. GE Energy's Nuclear Business is the global leader in boiling water reactor (BWR) technology. The experience-base of plants that have successfully achieved EPU includes Spain, Switzerland, Sweden, Germany and the United States. The GE experience-base includes fourteen BWRs with over fifty-eight reactor-years of operating experience at EPU conditions. Other than the expected plant modifications needed to accommodate higher steam flows, flow-induced vibration (FIV) has been identified as the major area of concern when up-rating. Two plants have experienced damage to their steam dryers that has lead to an extensive program to improve the understanding of the effects of up-rates. This program includes extensive in-plant data collection, the development of a scale model test facility to study components susceptible to FIV and improvements in analytical techniques for evaluating loading on reactor internals. As global energy demands increase, oil and gas prices escalate, and environmental concerns over greenhouse effects challenge us to find environmentally friendly sources of energy, Nuclear is the most viable and economical source of power in the world. With a focused effort on plant reliability, existing plants can undergo Extended Power Up-rate, and continue to meet the ever-increasing energy demands in the world. (author)

  15. THE EXTENDED VIRGO CLUSTER CATALOG

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Suk; Rey, Soo-Chang; Lee, Youngdae; Chung, Jiwon; Pak, Mina; Yi, Wonhyeong; Lee, Woong [Department of Astronomy and Space Science, Chungnam National University, 99 Daehak-ro, Daejeon 305-764 (Korea, Republic of); Jerjen, Helmut [Research School of Astronomy and Astrophysics, The Australian National University, Cotter Road, Weston, ACT 2611 (Australia); Lisker, Thorsten [Astronomisches Rechen-Institut, Zentrum für Astronomie der Universität Heidelberg (ZAH), Mönchhofstraße 12-14, D-69120 Heidelberg (Germany); Sung, Eon-Chang [Korea Astronomy and Space Science institute, 776 Daedeokdae-ro, Daejeon 305-348 (Korea, Republic of)

    2015-01-01

    We present a new catalog of galaxies in the wider region of the Virgo cluster, based on the Sloan Digital Sky Survey (SDSS) Data Release 7. The Extended Virgo Cluster Catalog (EVCC) covers an area of 725 deg{sup 2} or 60.1 Mpc{sup 2}. It is 5.2 times larger than the footprint of the classical Virgo Cluster Catalog (VCC) and reaches out to 3.5 times the virial radius of the Virgo cluster. We selected 1324 spectroscopically targeted galaxies with radial velocities less than 3000 km s{sup –1}. In addition, 265 galaxies that have been overlooked in the SDSS spectroscopic survey but have available redshifts in the NASA Extragalactic Database are also included. Our selection process secured a total of 1589 galaxies, 676 of which are not included in the VCC. The certain and possible cluster members are defined by means of redshift comparison with a cluster infall model. We employed two independent and complementary galaxy classification schemes: the traditional morphological classification based on the visual inspection of optical images and a characterization of galaxies from their spectroscopic features. SDSS u, g, r, i, and z passband photometry of all EVCC galaxies was performed using Source Extractor. We compare the EVCC galaxies with the VCC in terms of morphology, spatial distribution, and luminosity function. The EVCC defines a comprehensive galaxy sample covering a wider range in galaxy density that is significantly different from the inner region of the Virgo cluster. It will be the foundation for forthcoming galaxy evolution studies in the extended Virgo cluster region, complementing ongoing and planned Virgo cluster surveys at various wavelengths.

  16. Life Assessment and Life Extension of an Aircraft Wheel

    Directory of Open Access Journals (Sweden)

    M. Aghaie-Khafri

    2012-01-01

    Full Text Available The effect of heat treatment and shot peening on the fatigue life of an aluminum aircraft wheel was studied. The effect of residual stress and heat treatment on the fatigue of specimens was studied by means of fatigue testing, residual stress measurement, and fractography. Finite element simulation was used for life assessment and evaluation of the effect of surface treatments on the life extension of the aircraft wheel. The results obtained show that the operational life of the aircraft wheel extended by imposed compressive residual stress and aging treatment.

  17. A quantum extended Kalman filter

    International Nuclear Information System (INIS)

    Emzir, Muhammad F; Woolley, Matthew J; Petersen, Ian R

    2017-01-01

    In quantum physics, a stochastic master equation (SME) estimates the state (density operator) of a quantum system in the Schrödinger picture based on a record of measurements made on the system. In the Heisenberg picture, the SME is a quantum filter. For a linear quantum system subject to linear measurements and Gaussian noise, the dynamics may be described by quantum stochastic differential equations (QSDEs), also known as quantum Langevin equations, and the quantum filter reduces to a so-called quantum Kalman filter. In this article, we introduce a quantum extended Kalman filter (quantum EKF), which applies a commutative approximation and a time-varying linearization to systems of nonlinear QSDEs. We will show that there are conditions under which a filter similar to a classical EKF can be implemented for quantum systems. The boundedness of estimation errors and the filtering problem with ‘state-dependent’ covariances for process and measurement noises are also discussed. We demonstrate the effectiveness of the quantum EKF by applying it to systems that involve multiple modes, nonlinear Hamiltonians, and simultaneous jump-diffusive measurements. (paper)

  18. The Extended Mission Rover (EMR)

    Science.gov (United States)

    Shields, W.; Halecki, Anthony; Chung, Manh; Clarke, Ken; Frankle, Kevin; Kassemkhani, Fariba; Kuhlhoff, John; Lenzini, Josh; Lobdell, David; Morgan, Sam

    A key component in ensuring America's status as a leader in the global community is its active pursuit of space exploration. On the twentieth anniversary of Apollo 11, President George Bush challenged the nation to place a man on the moon permanently and to conduct human exploration of Mars in the 21st century. The students of the FAMU/FSU College of Engineering hope to make a significant contribution to this challenge, America's Space Exploration Initiative (SEI), with their participation in the NASA/USRA Advanced Design Program. The project selected by the 1991/1992 Aerospace Design group is the design of an Extended Mission Rover (EMR) for use on the lunar surface. This vehicle will serve as a mobile base to provide future astronauts with a 'shirt-sleeve' living and working environment. Some of the proposed missions are planetary surface exploration, construction and maintenance, hardware setup, and in situ resource experimentation. This vehicle will be put into use in the 2010-2030 time frame.

  19. Extended attention span training system

    Science.gov (United States)

    Pope, Alan T.; Bogart, Edward H.

    1991-01-01

    Attention Deficit Disorder (ADD) is a behavioral disorder characterized by the inability to sustain attention long enough to perform activities such as schoolwork or organized play. Treatments for this disorder include medication and brainwave biofeedback training. Brainwave biofeedback training systems feed back information to the trainee showing him how well he is producing the brainwave pattern that indicates attention. The Extended Attention Span Training (EAST) system takes the concept a step further by making a video game more difficult as the player's brainwaves indicate that attention is waning. The trainee can succeed at the game only by maintaining an adequate level of attention. The EAST system is a modification of a biocybernetic system that is currently being used to assess the extent to which automated flight management systems maintain pilot engagement. This biocybernetic system is a product of a program aimed at developing methods to evaluate automated flight deck designs for compatibility with human capabilities. The EAST technology can make a contribution in the fields of medical neuropsychology and neurology, where the emphasis is on cautious, conservative treatment of youngsters with attention disorders.

  20. The use of probabilistic safety assessment in the relicensing of nuclear power plants for extended lifetimes

    International Nuclear Information System (INIS)

    1990-02-01

    This document gives guidance in the major ways PSAs can be used for NPP life extension applications utilizing given PSA criteria. It also covers the specific steps for using presently available PSA models, data and criteria to assist life extension decision making and the research that could be carried out to extend the applicability of PSAs in this field. Refs, figs and tabs

  1. Sequential Extended Thoracoscopic Sympathicotomy for Palmo-Axillo-Plantar Hyperhidrosis.

    Science.gov (United States)

    Elalfy, Khaled; Emile, Sameh; Elfeki, Hossam; Elmetwally, Ahmed; Farag, Mohamed; Gado, Waleed

    2017-10-01

    Palmo-axillo-plantar hyperhidrosis (HH) exists in approximately 70% to 100% of patients complaining of HH. Many studies have documented variable effects of thoracoscopic sympathicotomy (TS) on plantar sweating. The present trial evaluated sequential extended thoracoscopic sympathicotomy for the treatment of palmo-axillo-plantar HH regarding its feasibility and outcome on each domain of HH, particularly the plantar domain METHODS: Forty-two patients with severe palmo-axillo-plantar HH underwent sequential extended (T3 to T12) thoracoscopic sympathicotomy. Improvement in HH was assessed using visual analog scale and iodine-starch test, and quality of life was evaluated using the Keller quality of life questionnaire preoperatively and 2 years postoperatively. Included were 16 men and 26 women with a mean age of 24.3 ± 5.3 years. The average preoperative VAS for the palmar, axillary, and plantar HH was 9 ± 0.66, which declined significantly (p < 0.0001) at 24 months of follow-up to a mean of 0.74 ± 0.4 for the palmar and axillary domains and to 1.26 ± 0.7 for plantar HH. Improvement in quality of life was observed in all patients at 24 months of follow-up as the overall median score decreased from 120.5 to 3.5. Sequential extended thoracoscopic sympathicotomy proved to be an effective method for the treatment of combined HH because it achieved satisfactory and sustained improvement of palmar, axillary, and plantar sweating. Although the benefits of sequential extended thoracoscopic sympathicotomy outweigh its drawbacks and technical difficulties, further prospective studies are required to ascertain the effectiveness of this new technique. Copyright © 2017 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

  2. Extended genomes: symbiosis and evolution.

    Science.gov (United States)

    Hurst, Gregory D D

    2017-10-06

    Many aspects of an individual's biology derive from its interaction with symbiotic microbes, which further define many aspects of the ecology and evolution of the host species. The centrality of microbes in the function of individual organisms has given rise to the concept of the holobiont-that an individual's biology is best understood as a composite of the 'host organism' and symbionts within. This concept has been further elaborated to posit the holobiont as a unit of selection. In this review, I critically examine whether it is useful to consider holobionts as a unit of selection. I argue that microbial heredity-the direct passage of microbes from parent to offspring-is a key factor determining the degree to which the holobiont can usefully be considered a level of selection. Where direct vertical transmission (VT) is common, microbes form part of extended genomes whose dynamics can be modelled with simple population genetics, but that nevertheless have subtle quantitative distinctions from the classic mutation/selection model for nuclear genes. Without direct VT, the correlation between microbial fitness and host individual fitness erodes, and microbe fitness becomes associated with host survival only (rather than reproduction). Furthermore, turnover of microbes within a host may lessen associations between microbial fitness with host survival, and in polymicrobial communities, microbial fitness may derive largely from the ability to outcompete other microbes, to avoid host immune clearance and to minimize mortality through phage infection. These competing selection pressures make holobiont fitness a very minor consideration in determining symbiont evolution. Nevertheless, the importance of non-heritable microbes in organismal function is undoubted-and as such the evolutionary and ecological processes giving rise to variation and evolution of the microbes within and between host individuals represent a key research area in biology.

  3. Extended Operation of Stirling Convertors at NASA Glenn Research Center

    Science.gov (United States)

    Oriti, Salvatore, M.

    2012-01-01

    NASA Glenn Research Center (GRC) has been supporting development of free-piston Stirling conversion technology for spaceflight electrical power generation since 1999. GRC has also been supporting the development of the Advanced Stirling Radioisotope Generator (ASRG) since 2006. A key element of the ASRG project is providing life, reliability, and performance data for the Advanced Stirling Convertor (ASC). The Thermal Energy Conversion branch at GRC is conducting extended operation of several free-piston Stirling convertors. The goal of this effort is to generate long-term performance data (tens of thousands of hours) on multiple units to build a life and reliability database. Currently, GRC is operating 18 convertors. This hardware set includes Technology Demonstration Convertors (TDCs) from Infinia Corporation, of which one pair (TDCs #13 and #14) has accumulated over 60,000 hr (6.8 years) of operation. Also under test are various Sunpower, Inc. convertors that were fabricated during the ASC development activity, including ASC-0, ASC-E (including those in the ASRG engineering unit), and ASC-E2. The ASC-E2s also completed, or are in progress of completing workmanship vibration testing, performance mapping, and extended operation. Two ASC-E2 units will also be used for durability testing, during which components will be stressed to levels above nominal mission usage. Extended operation data analyses from these tests are covered in this paper.

  4. NDE and plant life extension

    International Nuclear Information System (INIS)

    Liu, S.N.; Ammirato, F.V.; Nottingham, L.D.

    1991-01-01

    Component life extension is the process of making run-repair-replace decisions for plant components and includes a thorough analysis of the capability of the component to perform throughout the projected lifetime. For many critical plant components, nondestructive evaluation (NDE) is essential in determining whether the component can be operated safely and economically in the extended life period and to help utilities determine safe and economic inspection intervals. NDE technology is required for not only detecting defects that could grow to a size of concern during extended lifetimes, but also will be called upon to measure and monitor accumulating material degradation that strongly affects component reliability. This paper discusses the role of NDE in life extension by reviewing three examples--a reactor pressure vessel, steam turbine-generator rotors, and generator retaining rings. In each example, the contribution of NDE to life extension decisions is described. (author)

  5. Optimization Testbed Cometboards Extended into Stochastic Domain

    Science.gov (United States)

    Patnaik, Surya N.; Pai, Shantaram S.; Coroneos, Rula M.; Patnaik, Surya N.

    2010-01-01

    COMparative Evaluation Testbed of Optimization and Analysis Routines for the Design of Structures (CometBoards) is a multidisciplinary design optimization software. It was originally developed for deterministic calculation. It has now been extended into the stochastic domain for structural design problems. For deterministic problems, CometBoards is introduced through its subproblem solution strategy as well as the approximation concept in optimization. In the stochastic domain, a design is formulated as a function of the risk or reliability. Optimum solution including the weight of a structure, is also obtained as a function of reliability. Weight versus reliability traced out an inverted-S-shaped graph. The center of the graph corresponded to 50 percent probability of success, or one failure in two samples. A heavy design with weight approaching infinity could be produced for a near-zero rate of failure that corresponded to unity for reliability. Weight can be reduced to a small value for the most failure-prone design with a compromised reliability approaching zero. The stochastic design optimization (SDO) capability for an industrial problem was obtained by combining three codes: MSC/Nastran code was the deterministic analysis tool, fast probabilistic integrator, or the FPI module of the NESSUS software, was the probabilistic calculator, and CometBoards became the optimizer. The SDO capability requires a finite element structural model, a material model, a load model, and a design model. The stochastic optimization concept is illustrated considering an academic example and a real-life airframe component made of metallic and composite materials.

  6. Extending and implementing the Persistent ID pillars

    Science.gov (United States)

    Car, Nicholas; Golodoniuc, Pavel; Klump, Jens

    2017-04-01

    The recent double decade anniversary of scholarly persistent identifier use has triggered journal special editions such as "20 Years of Persistent Identifiers". For such a publication, it is apt to consider the longevity of some persistent identifier (PID) mechanisms (Digital Object Identifiers) and the partial disappearance of others (Life Sciences IDs). We have previously postulated a set of "PID Pillars" [1] which are design principles aimed at ensuring PIDs can survive technology and social change and thus persist for the long term that we have drawn from our observations of PIDs at work over many years. The principles: describe how to ensure identifiers' system and organisation independence; codify the delivery of essential PID system functions; mandate a separation of PID functions from data delivery mechanisms; and require generation of policies detailing how change is handled. In this presentation, first we extend on our previous work of introducing the pillars by refining their descriptions, giving specific suggestions for each and presenting some work that addresses them. Second, we propose a baseline data model for persistent identifiers that, if used, would assist the separation of PID metadata and PID system functioning. This would allow PID system function specifics to change over time (e.g. resolver services or even resolution protocols) and yet preserve the PIDs themselves. Third, we detail our existing PID system — the PID Service [2] — that partially implements the pillars and describe both its successes and shortcomings. Finally, we describe our planned next-generation system that will aim to use the baseline data model and fully implement the pillars.

  7. Life-cycle management

    International Nuclear Information System (INIS)

    Economic factors have contributed to the decision to close Yankee Rowe, San Onofre Unit 1, and Trojan nuclear plants. As nuclear plants age, uncertainties related to major component and system replacement can affect their capital cost contribution to the price of electricity. These costs, their timing, and associated uncertainties can be prohibitive if the remaining plant life is too short. However, these costs may be acceptable if plant service life is extended. Life-cycle management (LCM) is a method of evaluating those options which ultimately affect the useful life of a power plant. This paper presents the methods and an example of an LCM evaluation of a Salt Water Service Water System. Cost-benefit analyses were developed by quantifying age-related degradation mechanisms for various lining and replacement materials, determining their probabilistic life distributions, and developing service repair/replacement alternatives. For each alternative, the maintenance requirements and life expectancy and their associated costs were determined. The probabilistic approach and sensitivity analyses demonstrated the confidence in and the economic value of each alternative. To determine the effect of license renewal and to fully appreciate the value of the repair/replacement alternatives, the PVRR costs were determined with and without a 20-year license renewal. The use of this method also allowed the identification of technical and cost parameters critical to the decision making process

  8. Life insurance

    OpenAIRE

    ČERNÁ, Lenka

    2009-01-01

    Bachelor's thesis deals with the life insurance market in the Czech Republic. I compared the different insurance products life insurance among themselves. And these products is the formula published in the scientific literature.

  9. Life's crucible.

    Science.gov (United States)

    Radetsky, P

    1998-02-01

    Research by German chemists Gunter Wachtershauser and Claudia Huber about the origins of life is reviewed. Other theories about the beginning of life on Earth are examined with comments by noted researchers.

  10. Extended family and friendship support and suicidality among African Americans.

    Science.gov (United States)

    Nguyen, Ann W; Taylor, Robert Joseph; Chatters, Linda M; Taylor, Harry Owen; Lincoln, Karen D; Mitchell, Uchechi A

    2017-03-01

    This study examined the relationship between informal social support from extended family and friends and suicidality among African Americans. Logistic regression analysis was based on a nationally representative sample of African Americans from the National Survey of American Life (N = 3263). Subjective closeness and frequency of contact with extended family and friends and negative family interaction were examined in relation to lifetime suicide ideation and attempts. Subjective closeness to family and frequency of contact with friends were negatively associated with suicide ideation and attempts. Subjective closeness to friends and negative family interaction were positively associated with suicide ideation and attempts. Significant interactions between social support and negative interaction showed that social support buffers against the harmful effects of negative interaction on suicidality. Findings are discussed in relation to the functions of positive and negative social ties in suicidality.

  11. Extending Abdominal Aortic Aneurysm Detection to Older Age Groups

    DEFF Research Database (Denmark)

    Makrygiannis, Georgios; Labalue, Philippe; Erpicum, Marie

    2016-01-01

    . Current screening policies (e.g., men aged 65-74 years), however, do not account for aging and increased life expectancy of Western populations. This study investigated AAA detection by extending the target population to older age groups (75-85 years). METHODS: AAA screening was conducted in the County......-74 age group but rose to 7.3% in the age-extended group (75-85 years). Further in addition to age, height, current smoking, history of coronary artery disease, hypercholesterolemia, peripheral artery disease of the lower limbs, and varicose veins were significantly associated with the presence of AAA......BACKGROUND: There is evident benefit in terms of reduced aneurysm-related mortality from screening programs of abdominal aortic aneurysm (AAA) in men aged 65 years and more. Recent studies in the United Kingdom and Sweden have shown a decline of the prevalence of AAA in the general population...

  12. BWR operation for life extension

    International Nuclear Information System (INIS)

    Stancavage, P.

    1987-01-01

    Most nuclear power plant life extension studies conducted to date focus on the technology, licensing, and economics of extended service life. The most significant factor in plant longevity, however, is proper operation and maintenance. This paper highlights the benefits of boiling water reactor (BWR) operation for life extension and discusses specific recommendations that will enhance the prospects for safe, reliable, and economic power production in the long term. The benefits of BWR operation for life extension include a lower cost of electric energy production, increased capacity and availability factors, a lower forced outage rate, and reduced occupational exposure to radiation. Operating experience and advanced in technology have provided a wealth of knowledge that can be used to develop specific recommendations for adding years to the expected life of BWR plants. This paper discusses key factors in operation for life extension

  13. Statistical inference on residual life

    CERN Document Server

    Jeong, Jong-Hyeon

    2014-01-01

    This is a monograph on the concept of residual life, which is an alternative summary measure of time-to-event data, or survival data. The mean residual life has been used for many years under the name of life expectancy, so it is a natural concept for summarizing survival or reliability data. It is also more interpretable than the popular hazard function, especially for communications between patients and physicians regarding the efficacy of a new drug in the medical field. This book reviews existing statistical methods to infer the residual life distribution. The review and comparison includes existing inference methods for mean and median, or quantile, residual life analysis through medical data examples. The concept of the residual life is also extended to competing risks analysis. The targeted audience includes biostatisticians, graduate students, and PhD (bio)statisticians. Knowledge in survival analysis at an introductory graduate level is advisable prior to reading this book.

  14. Managing BWR plant life extension

    International Nuclear Information System (INIS)

    Ianni, P.W.; Kiss, E.

    1985-01-01

    Recent studies have confirmed that extending the useful life of a large nuclear plant can be justified with very high cost benefit ratio. In turn, experience with large power plant systems and equipment has shown that a well-integrated and -managed plan is essential in order to achieve potential economic benefits. Consequently, General Electric's efforts have been directed at establishing a life extension plan that considers alternative options and cost-effective steps that can be taken in early life, those appropriate during middle life, and those required in late life. This paper briefly describes an approach designed to provide the plant owner a maximum of flexibility in developing a life extension plan

  15. Picturing Life

    OpenAIRE

    Molly Bathje MS, OTR/L

    2013-01-01

    The cover art of the summer 2013 issue of The Open Journal of Occupational Therapy provided by Jonathan Darnall reflects his unique life perspective, current roles, and values. An exploration of Jon’s life experience reveals how creative arts, including photography, have positively influenced his life and inform OT practitioners about the benefits of photography as an intervention and an occupation.

  16. Fertigação em mudas de citros utilizando-se mangueiras e microtubos sob regime de escoamento turbulento Fertigation on citrus seedlings using hoses and microtubes under turbulent flow regime

    Directory of Open Access Journals (Sweden)

    Wanderley J. Souza

    2011-08-01

    Full Text Available A irrigação localizada utilizando-se microtubo como emissor operando em regime de escoamento turbulento, pode ser uma alternativa viável, tanto técnica como economicamente para a produção de mudas de citros. Objetivou-se, com este trabalho, avaliar o desempenho de um sistema de fertigação na produção de mudas de laranja em viveiro projetado pelo modelo matemático universal, utilizando-se microtubos como emissores, sob regime de escoamento turbulento e comparar o desenvolvimento das plantas fertigadas por microtubos com o sistema em que se utiliza o método tradicional com mangueiras. No dimensionamento do comprimento dos emissores considerou-se o coeficiente K de dissipação de energia localizada através de um microtubo com diâmetro interno de 0,761 mm. O sistema de fertigação apresentou bom desempenho, com valores de grau de entupimento, uniformidade de Christiansen e uniformidade de emissão iguais a 0,50; 99,95 e 98,21%, respectivamente, após 160 dias de estudo. As plantas cultivadas via fertigação com microtubos e mangueiras, não apresentaram diferenças no que se refere ao diâmetro do caule e à altura. Desta forma, o uso de microtubo sob escoamento turbulento apresentou viabilidade técnica para fertigação.The use of localized irrigation using microtube as emitter under turbulent flow regime can be a technically feasible alternative. The objective of this study was to evaluate the performance of a fertigation system in nursery of citrus plants (greenhouse projected by universal mathematical model, using the microtubes as emitters, under turbulent flow rate and to compare the development of the fertigated plants by microtubes to the system that use the traditional method with hoses. In the size of the length of the emitters was considered the K coefficient of localized energy dissipation using a microtube with internal diameter of 0,761 mm. The fertigation system presented great performance with clogging degree

  17. Evaluation of different oxygen, carbon dioxide and nitrogen combinations employed to extend the shelf life of fresh-cut collard greens Avaliação de diferentes combinações de oxigênio, gás carbônico e nitrogênio utilizadas no aumento de vida de prateleira de couve minimamente processada

    Directory of Open Access Journals (Sweden)

    Celso L. Moretti

    2003-12-01

    Full Text Available Collard greens (Brassica oleracea var. acephala "Manteiga" were harvested in commercial fields in Brasilia, Brazil, aiming to evaluate different oxygen, carbon dioxide and nitrogen combinations to extend the shelf life of the fresh-cut product. After harvest, leaves were taken to the postharvest laboratory, selected for external blemishes and minimally processed (3 mm thick inside a cold room (13±2°C. After processing, fresh-cut collard greens were stored under two controlled atmosphere (CA conditions (3% O2, 4% CO2; 5% O2, 5% CO2/balance N2, and normal air (control, at 5°C (95±2% RH, for six days. Daily, minimally processed collard greens were evaluated for total vitamin C, total chlorophyll, total soluble solids content, and titratable acidity. Total vitamin C content decreased for all treatments during the storage period. Storage under CA conditions delayed total vitamin C degradation for both atmospheres studied. At the end of the storage period, fresh-cut collard greens stored under 3% O2, 4% CO2 showed around 25% and 56% more vitamin C than the material stored under 5% O2, 5% CO2 and control, respectively. Total chlorophyll content decreased during the storage period. At the end of the experiment, fresh-cut collard greens stored under 3% O2, 4% CO2 showed 24% and 45% more total chlorophyll than the product stored under 5% O2, 5% CO2 and control, respectively. CA storage delayed organic acid degradation. On the sixth day, fresh-cut collard greens stored under 3% O2, 4% CO2 presented around 44% more organic acids than control. Total soluble solids content were not significantly affected.Folhas de couve (Brassica oleracea var. acephala "Manteiga" foram obtidas em campos de produção comercial em Brasília, DF, com o objetivo de avaliar diferentes combinações de oxigênio, dióxido de carbono e nitrogênio para estender a vida de prateleira do produto minimamente processado. Após colhidas, as folhas foram levadas ao laboratório de p

  18. Management of neurovascular complications in extended skull base surgery.

    Science.gov (United States)

    Leonetti, J P; Smith, P G; Grubb, R L

    1989-05-01

    Combined oncologic approaches to the skull base now permit resection of extensive basicranial neoplasms. Despite advances in microsurgical techniques, disabling or life-threatening complications are still encountered in such surgery. Successful management of these sequelae is dependent upon meticulous intraoperative care and compulsive postoperative clinical assessment. Perioperative neurovascular complications were recorded in 154 consecutive skull base procedures. The most frequent severe complication was cerebral edema, which occasionally required surgical intervention. Dysphagia was the most common complication noted in the late postoperative period. Based upon this review, the management and methods found to minimize the incidence of various perioperative neurovascular complications related to extended skull base surgery are described.

  19. Extended Producer Responsibility in the Aviation Sector

    OpenAIRE

    Brito, Marisa; Laan, Erwin; Irion, B.D.

    2007-01-01

    textabstractIn this paper we investigate recent initiatives with respect to extended producer responsibility in the aviation sector. We compare those with the existing practices in the automobile sector and the emerging regulations in the shipping sector. We describe the challenges and the lessons to be learned from the evolution and state of extended producer responsibility in these two industries.

  20. Extended, Embodied Cognition and Second Language Acquisition

    Science.gov (United States)

    Atkinson, Dwight

    2010-01-01

    A "cognitivist" approach to cognition has traditionally dominated second language acquisition (SLA) studies. In this article, I examine two alternative approaches--"extended cognition" and "embodied cognition"--for how they might help us conceptualize SLA. More specifically, I present: (i) summaries of extended and embodied cognition, followed by…

  1. Pendulum motions of extended lunar space elevator

    Science.gov (United States)

    Burov, A. A.; Kosenko, I. I.

    2014-09-01

    In the usual everyday life, it is well known that the inverted pendulum is unstable and is ready to fall to "all four sides," to the left and to the right, forward and backward. The theoretical studies and the lunar experience of moon robots and astronauts also confirms this property. The question arises: Is this property preserved if the pendulum is "very, very long"? It turns out that the answer is negative; namely, if the pendulum length significantly exceeds the Moon radius, then the radial equilibria at which the pendulum is located along the straight line connecting the Earth and Moon centers are Lyapunov stable and the pendulum does not fall in any direction at all. Moreover, if the pendulum goes beyond the collinear libration points, then it can be extended and manufactured from cables. This property was noted by F. A. Tsander and underlies the so-called lunar space elevator (e.g., see [1]). In the plane of the Earth and Moon orbits, there are some other equilibria which turn out to be unstable. The question is, Are there equilibria at which the pendulum is located outside the orbital plane? In this paper, we show that the answer is positive, but such equilibria are unstable in the secular sense. We also study necessary conditions for the stability of lunar pendulum oscillations in the plane of the lunar orbit. It was numerically discovered that stable and unstable equilibria alternate depending on the oscillation amplitude and the angular velocity of rotation. The study of the lunar elevator dynamics originates in [2]. The concept of lunar elevator was developed in detail in [3, 4]. Several classes of equilibria with the finiteness of the Moon size taken into account were studied in [5]. The possibility of location of an orbital station fixed to the Moon surface by a pair of tethers was investigated in [6]. The problem of orientation of the terminal station of the lunar space elevator was studied in [7]. The influence of the tether length variations on the

  2. Extended cycle hormonal contraception in adolescents.

    Science.gov (United States)

    Sucato, Gina S; Gerschultz, Kelly L

    2005-10-01

    There is increasing interest in the use of extended cycles of hormonal contraception to manage menstrual cycle-related complaints in adolescents and to accommodate the menstrual preferences of patients using hormonal contraception. This review summarizes recent findings related to the use of extended cycles and highlights their relevance to adolescents. Many adolescents would prefer to menstruate less frequently. Among health care providers who prescribe hormonal contraceptives, the majority believe suppressing withdrawal bleeding is well tolerated and prescribe extended cycling regimens to their patients. Shortening or eliminating the hormone-free interval results in greater ovarian suppression and thus may increase contraceptive efficacy. Studies in adult women have not identified changes in metabolic parameters beyond what would be expected from traditional cyclic use. New endometrial biopsy data have found no pathologic changes; most women using an extended cycle had atrophic endometriums. Extended cycling is frequently associated with breakthrough bleeding. In some women, this can be managed with a brief hormone-free interval. Recent findings demonstrate high levels of interest in extended cycling among adolescents and providers, and continue to add to the growing body of literature supporting the safety and improved contraceptive efficacy of extended regimens. Further research is warranted to focus on issues including cancer, thrombotic disease and fertility, and should enroll a sufficient adolescent sample.

  3. The symmetric extendibility of quantum states

    International Nuclear Information System (INIS)

    Nowakowski, Marcin L

    2016-01-01

    Studies on the symmetric extendibility of quantum states have become particularly important in the context of the analysis of one-way quantum measures of entanglement, and the distillability and security of quantum protocols. In this paper we analyze composite systems containing a symmetric extendible part, with particular attention devoted to the one-way security of such systems. Further, we introduce a new one-way entanglement monotone based on the best symmetric approximation of a quantum state and the extendible number of a quantum state. We underpin these results with geometric observations about the structures of multi-party settings which posses substantial symmetric extendible components in their subspaces. The impossibility of reducing the maximal symmetric extendibility by means of the one-way local operations and classical communication method is pointed out on multiple copies. Finally, we state a conjecture linking symmetric extendibility with the one-way distillability and security of all quantum states, analyzing the behavior of a private key in the neighborhood of symmetric extendible states. (paper)

  4. Extended Cognitive System and Epistemic Subject

    Directory of Open Access Journals (Sweden)

    Trybulec Barbara

    2015-03-01

    Full Text Available The concept of an extended cognitive system is central to contemporary studies of cognition. In the paper I analyze the place of the epistemic subject within the extended cognitive system. Is it extended as well? In answering this question I focus on the differences between the first and the second wave of arguments for the extended mind thesis. I argue that the position of Cognitive Integration represented by Richard Menary is much more intuitive and fruitful in analyses of cognition and knowledge than the early argument formulated by Andy Clark and David Chalmers. Cognitive Integration is compatible with virtue epistemology of John Greco’s agent reliabilism. The epistemic subject is constituted by its cognitive character composed of an integrated set of cognitive abilities and processes. Some of these processes are extended, they are a manipulation of external informational structures and, as such, they constitute epistemic practices. Epistemic practices are normative; to conduct them correctly the epistemic subject needs to obey epistemic norms embedded in the cultural context. The epistemic subject is not extended because of the casual coupling with external informational artifacts which extend his mind from inside the head and into the world. Rather, cognitive practices constitute the subject’s mind, they transform his cognitive abilities, and this is what makes the mind and epistemic subject “extended”.

  5. Picturing Life

    Directory of Open Access Journals (Sweden)

    Molly Bathje MS, OTR/L

    2013-08-01

    Full Text Available The cover art of the summer 2013 issue of The Open Journal of Occupational Therapy provided by Jonathan Darnall reflects his unique life perspective, current roles, and values. An exploration of Jon’s life experience reveals how creative arts, including photography, have positively influenced his life and inform OT practitioners about the benefits of photography as an intervention and an occupation.

  6. Extended evolutionary psychology: the importance of transgenerational developmental plasticity.

    Science.gov (United States)

    Stotz, Karola

    2014-01-01

    What kind mechanisms one deems central for the evolutionary process deeply influences one's understanding of the nature of organisms, including cognition. Reversely, adopting a certain approach to the nature of life and cognition and the relationship between them or between the organism and its environment should affect one's view of evolutionary theory. This paper explores this reciprocal relationship in more detail. In particular it argues that the view of living and cognitive systems, especially humans, as deeply integrated beings embedded in and transformed by their genetic, epigenetic (molecular and cellular), behavioral, ecological, socio-cultural and cognitive-symbolic legacies calls for an extended evolutionary synthesis that goes beyond either a theory of genes juxtaposed against a theory of cultural evolution and or even more sophisticated theories of gene-culture coevolution and niche construction. Environments, particularly in the form of developmental environments, do not just select for variation, they also create new variation by influencing development through the reliable transmission of non-genetic but heritable information. This paper stresses particularly views of embodied, embedded, enacted and extended cognition, and their relationship to those aspects of extended inheritance that lie between genetic and cultural inheritance, the still gray area of epigenetic and behavioral inheritance systems that play a role in parental effect. These are the processes that can be regarded as transgenerational developmental plasticity and that I think can most fruitfully contribute to, and be investigated by, developmental psychology.

  7. Preventing catastrophes in spatially extended systems through ...

    Indian Academy of Sciences (India)

    2015-01-29

    Scientific Reports (Nature) 4, 4308] on taming explosive growth in spatially extended systems. Specifically, we consider collections of relaxation oscillators, which are relevant to modelling phenomena ranging from ...

  8. PREVALENCE OF EXTENDED SPECTRUM β-LACTAMASES ...

    African Journals Online (AJOL)

    DR. AMINU

    ABSTRACT. Confirmed variants of enterobacteriaceae isolated from 143 patients that attended Murtala. Mohammed Specialist Hospital Kano, were screened for extended spectrum β-lactamases (ESBLs) production using Clinical Laboratory Standards Institute (CLSI) breakpoint. Suspected ESBLs producers were ...

  9. Extended Adjuvant Therapy for Breast Cancer

    Science.gov (United States)

    An NCI Cancer Currents blog on findings from a recent clinical trial which showed that extending adjuvant therapy with an aromatase inhibitor can have important benefits for some women with early-stage cancer.

  10. Some results for extended Jacobi polynomials

    International Nuclear Information System (INIS)

    Khan, I.A.

    1991-06-01

    In this paper, some contiguous function relations and generating functions have been established for extended Jacobi polynomials. The results obtained here, are of very general nature. (author). 5 refs

  11. Structural and Conservation Effort Alternatives to Extending Jatigede Reservoir Service Lifetime by Limiting Sedimentation

    Science.gov (United States)

    Rohmat, F. I.; Hadihardaja, I. K.; Rohmat, D.

    2013-12-01

    Jatigede Reservoir, which is being constructed in West Java province, Indonesia, is planned to begin operation in late 2013. It is designed to provide 90,000 ha of paddy field irrigation, 100 MW power generation, and flood control. However, previous studies indicate that the reservoir will only have a service life of 7 to 30 years, rather than its 100-year design service life. One reason is the high rate of sedimentation, which is predicted to reach more than 8 million tons per year because of changes in land use in the watershed. This condition is aggravated by the removal of the flushing gate on the bottom of the dam. This study examines alternatives to extend the service life of Jatigede Reservoir, including a structural solution (extending and raising the irrigation inlet to increase the dead storage), watershed conservation, and a combination of these alternatives. The structural effort may extend the reservoir's service life by 10 to 20 years, but with considerable effect on increasing flooding and drought risk by reduced live storage. Structural options need to be combined with conservation options in order to extend the service life of Jatigede Reservoir to the desired range.

  12. Group life insurance

    CERN Multimedia

    2013-01-01

    The CERN Administration wishes to inform staff members and fellows having taken out optional life insurance under the group contract signed by CERN that the following changes to the rules and regulations entered into force on 1 January 2013:   The maximum age for an active member has been extended from 65 to 67 years. The beneficiary clause now allows insured persons to designate one or more persons of their choice to be their beneficiary(-ies), either at the time of taking out the insurance or at a later date, in which case the membership/modification form must be updated accordingly. Beneficiaries must be clearly identified (name, first name, date of birth, address).   The membership/modification form is available on the FP website: http://fp.web.cern.ch/helvetia-life-insurance For further information, please contact: Valentina Clavel (Tel. 73904) Peggy Pithioud (Tel. 72736)

  13. Musical Manipulations and the Emotionally Extended Mind

    Directory of Open Access Journals (Sweden)

    Joel Krueger

    2015-05-01

    Full Text Available I respond to Kersten's criticism in his article "Music and Cognitive Extension" of my approach to the musically extended emotional mind in Krueger (2014. I specify how we manipulate—and in so doing, integrate with—music when, as active listeners, we become part of a musically extended cognitive system. I also indicate how Kersten's account might be enriched by paying closer attention to the way that music functions as an environmental artifact for emotion regulation.

  14. Possibility of extending space-time coordinates

    International Nuclear Information System (INIS)

    Wang Yongcheng.

    1993-11-01

    It has been shown that one coordinate system can describe a whole space-time region except some supersurfaces on which there are coordinate singularities. The conditions of extending a coordinate from real field to complex field are studied. It has been shown that many-valued coordinate transformations may help us to extend space-time regions and many-valued metric functions may make one coordinate region to describe more than one space-time regions. (author). 11 refs

  15. Life sciences

    International Nuclear Information System (INIS)

    Day, L.

    1991-04-01

    This document is the 1989--1990 Annual Report for the Life Sciences Divisions of the University of California/Lawrence Berkeley Laboratory. Specific progress reports are included for the Cell and Molecular Biology Division, the Research Medicine and Radiation Biophysics Division (including the Advanced Light Source Life Sciences Center), and the Chemical Biodynamics Division. 450 refs., 46 figs

  16. Life sciences

    Energy Technology Data Exchange (ETDEWEB)

    Day, L. (ed.)

    1991-04-01

    This document is the 1989--1990 Annual Report for the Life Sciences Divisions of the University of California/Lawrence Berkeley Laboratory. Specific progress reports are included for the Cell and Molecular Biology Division, the Research Medicine and Radiation Biophysics Division (including the Advanced Light Source Life Sciences Center), and the Chemical Biodynamics Division. 450 refs., 46 figs. (MHB)

  17. Extended Access List untuk Mengendalikan Trafik Jaringan

    Directory of Open Access Journals (Sweden)

    Hari Antoni Musril

    2016-12-01

    Full Text Available Keamana jaringan komputer saat ini menjadi hal penting untuk diterapkan. Banyak organisasi yang telah menjadikan teknologi informasi sebagai bahagian penting dalam menunjang aktivitasnya. Akses pengguna yang tidak dibatasi menjadi ancaman bagi sebuah organisasi, karena banyak data dan informasi penting yang tersebar dalam perangkat jaringan komputer di organisasi tersebut dapat disusupi oleh pihak yang tidak berwenang. Salah satu usaha yang dapat dilakukan adalah dengan menerapkan extended access list yang merupakan salah satu bagian dari metode access control list. Extended access list dapat menyaring lalu lintas data suatu jaringan dengan mengontrol apakah paket-paket tersebut dilewatkan atau dihentikan. Extended access list juga dapat menjamin keamanan untuk setiap komputer sehingga jalur komunikasi serta hak akses setiap komputer dapat berjalan dengan baik. Extended access list memungkinkan penyaringan berdasarkan sumber atau alamat tujuan, protokol yang dipilih, port yang digunakan, dan apakah koneksi sudah ditetapkan. Tulisan ini membahas penerapan extended access list dalam jaringan supaya dapat melakukan filter terhadap paket data yang melewati jaringan. Penerapannya menggunakan software Packet Tracer 6.1.1 untuk membuat prototipe jaringan dan mensimulasikannya. Sehingga nanti dapat diterapkan pada jaringan yang sebenarnya. List yang dibangun pada penelitian ini diterapkan untuk protokol antara lain : TCP (WWW, FTP, Telnet, SMTP, POP3, UDP (DNS, dan ICMP (Ping. Hasilnya didapatkan extended access list yang dikonfigurasi pada router dalam topologi penelitian ini mampu melakukan filter terhadap paket yang melewati jaringan. Hasil konfigurasinya sangat spesifik, sehingga penerapan hak akses permit dan deny dapat dilakukan sesuai dengan aturan dan skenario yang dirancang.

  18. Four Ways Life Extension will Change Our Relationship with Death.

    Science.gov (United States)

    Davis, John K

    2016-03-01

    Discussions of life extension ethics have focused mainly on whether an extended life would be desirable to have, and on the social consequences of widely available life extension. I want to explore a different range of issues: four ways in which the advent of life extension will change our relationship with death, not only for those who live extended lives, but also for those who cannot or choose not to. Although I believe that, on balance, the reasons in favor of developing life extension outweigh the reasons against doing so (something I won't argue for here), most of these changes probably count as reasons against doing so. First, the advent of life extension will alter the human condition for those who live extended lives, and not merely by postponing death. Second, it will make death worse for those who lack access to life extension, even if those people live just as long as they do now. Third, for those who have access to life extension but prefer to live a normal lifespan because they think that has advantages, the advent of life extension will somewhat reduce some of those advantages, even if they never use life extension. Fourth, refusing life extension turns out to be a form of suicide, and this will force those who have access to life extension but turn it down to choose between an extended life they don't want and a form of suicide they may (probably mistakenly) consider immoral. © 2015 John Wiley & Sons Ltd.

  19. Factors Associated With Extended Breastfeeding in India.

    Science.gov (United States)

    Mehta, Arpit R; Panneer, Sigamani; Ghosh-Jerath, Suparna; Racine, Elizabeth F

    2017-02-01

    Extended breastfeeding duration is common in India. Extended breastfeeding protects the infant from infectious disease and promotes child spacing. In the 1990s, the median breastfeeding duration in India was 24 months. Research aim: This study aimed to investigate the median duration of breastfeeding in India and to identify the factors associated with extended breastfeeding to 24 months as recommended by the World Health Organization. This cross-sectional data analysis used nationally representative data from the 2011-2012 Indian Human Development Survey II. The outcome in this study was extended breastfeeding defined as breastfeeding to 24 months or more. Multivariate logistic regression was used to identify the factors associated with extended breastfeeding. The median duration of breastfeeding was 12 months; approximately 25% of women breastfed 24 months or more. Women were at greater odds of breastfeeding 24 months or more if the infant was a boy compared with a girl, if the women lived in a rural area compared with an urban area, if the women were married at a young age (marriage), and if the delivery was assisted by a friend or relative compared with a doctor. The median duration of breastfeeding has decreased by 50% from 1992-1993 to 2011-2012. The women who continue to breastfeed 24 months or more tend to be more traditional (i.e., living in rural areas, marrying young, and having family/friends as birth attendants). Further research to study the health effect of decreased breastfeeding duration is warranted.

  20. Paris law parameter identification based on the Extended Kalman Filter

    Directory of Open Access Journals (Sweden)

    Melgar M.

    2016-01-01

    Full Text Available Aircraft structures are commonly subjected to repeated loading cycles leading to fatigue damage. Fatigue data can be extrapolated by fatigue models which are adopted to describe the fatigue damage behaviour. Such models depend on their parameters for accurate prediction of the fatigue life. Therefore, several methods have been developed for estimating the model parameters for both linear and nonlinear systems. It is useful for a broad class of parameter identification problems when the dynamic model is not known. In this paper, the Paris law is used as fatigue-crack-length growth model on a metallic component under loading cycles. The Extended Kalman Filter (EKF is proposed as estimation method. Simulated crack length data is used to validate the estimation method. Based on experimental data obtained from fatigue experiment, the crack length and model parameters are estimated. Accurate model parameters allow a more realistic prediction of the fatigue life, consequently, the remaining useful life (RUL of component can be accurately computed. In this sense, maintenance performance could be improved.

  1. The validity of the extended energy principle

    International Nuclear Information System (INIS)

    Chance, M.S.; Johnson, J.L.; Kulsrud, R.M.

    1994-04-01

    A recent analysis of plasma stability based on modifications of the extended energy principle for magnetohydrodynamic stability led to conclusions that are too optimistic. The original interpretation of this principle is indeed applicable. The present analysis demonstrates explicitly the fallacy of using the wrong functional for δW in the extended energy principle. It then shows that the original energy principle functional δW B is also obtained for a model in which a surface mass is incorporated to provide pressure balance. This work therefore indicates, but does not prove, that the eigenfunctions that are obtained from a minimization of the extended energy principle with the proper kinetic energy norm provide a good representation of what would be achieved with an exact treatment

  2. Extending Double Optical Gating to the Midinfrared

    Science.gov (United States)

    Gorman, Timothy; Camper, Antoine; Agostini, Pierre; Dimauro, Louis

    2015-05-01

    In the past decade there has been great interest in creating broadband isolated attosecond pulses (IAPs). Primarily these IAPs have been generated using Ti:Sapphire 800nm short pulses, namely through spatiotemporal gating with the attosecond lighthouse technique, amplitude gating, polarization gating, and double optical gating (DOG). Here we present theoretical calculations and experimental investigations into extending DOG to using a 2 μm driving wavelength, the benefits of which include extended harmonic cutoff and longer input driving pulse durations. It is proposed that broadband IAPs with cutoffs extending up to 250 eV can be generated in Argon by using >30 fs pulses from the passively-CEP stabilized 2 μm idler out of an optical parametric amplifier combined with a collinear DOG experimental setup.

  3. Extended inflation from higher-dimensional theories

    International Nuclear Information System (INIS)

    Holman, R.; Kolb, E.W.; Vadas, S.L.; Wang, Y.

    1991-01-01

    We consider the possibility that higher-dimensional theories may, upon reduction to four dimensions, allow extended inflation to occur. We analyze two separate models. One is a very simple toy model consisting of higher-dimensional gravity coupled to a scalar field whose potential allows for a first-order phase transition. The other is a more sophisticated model incorporating the effects of nontrivial field configurations (monopole, Casimir, and fermion bilinear condensate effects) that yield a nontrivial potential for the radius of the internal space. We find that extended inflation does not occur in these models. We also find that the bubble nucleation rate in these theories is time dependent unlike the case in the original version of extended inflation

  4. Extended inflation from higher dimensional theories

    International Nuclear Information System (INIS)

    Holman, R.; Kolb, E.W.; Vadas, S.L.; Wang, Yun.

    1990-04-01

    The possibility is considered that higher dimensional theories may, upon reduction to four dimensions, allow extended inflation to occur. Two separate models are analayzed. One is a very simple toy model consisting of higher dimensional gravity coupled to a scalar field whose potential allows for a first-order phase transition. The other is a more sophisticated model incorporating the effects of non-trivial field configurations (monopole, Casimir, and fermion bilinear condensate effects) that yield a non-trivial potential for the radius of the internal space. It was found that extended inflation does not occur in these models. It was also found that the bubble nucleation rate in these theories is time dependent unlike the case in the original version of extended inflation

  5. An extended range neutron rem counter

    International Nuclear Information System (INIS)

    Birattari, C.; Nuccetelli, C.; Pelliccioni, M.; Silari, M.

    1990-01-01

    Extensive Monte Carlo calculations have been carried out to assess the possibility of extending the sensitivity of a neutron rem counter of the Andersson-Braun type up to several hundred MeV. The validity of the model adopted has first been checked by comparing with experimental data the calculated response curve and the angular dependence of the sensitivity for a well known commercial rem counter. Next, a number of modifications to the configuration of the moderator-attenuator have been investigated. The response functions and angular distributions produced by two simple solutions yielding an instrument with a sensitivity extended up to 400 MeV are presented. The response of the original rem counter and of its two modified versions to nine test spectra has also been calculated. The resulting instrument is transportable rather than portable, but the availability of an extended range neutron survey meter would be of great advantage at medium and high energy particle accelerator facilities. (orig.)

  6. Remarkable connections between extended magnetohydrodynamics models

    Energy Technology Data Exchange (ETDEWEB)

    Lingam, M., E-mail: manasvi@physics.utexas.edu; Morrison, P. J., E-mail: morrison@physics.utexas.edu; Miloshevich, G., E-mail: gmilosh@physics.utexas.edu [Department of Physics and Institute for Fusion Studies, The University of Texas at Austin, Austin, Texas 78712 (United States)

    2015-07-15

    Through the use of suitable variable transformations, the commonality of all extended magnetohydrodynamics (MHD) models is established. Remarkable correspondences between the Poisson brackets of inertialess Hall MHD and inertial MHD (which has electron inertia, but not the Hall drift) and extended MHD (which has both effects) are established. The helicities (two in all) for each of these models are obtained through these correspondences. The commonality of all the extended MHD models is traced to the existence of two Lie-dragged 2-forms, which are closely associated with the canonical momenta of the two underlying species. The Lie-dragging of these 2-forms by suitable velocities also leads to the correct equations of motion. The Hall MHD Poisson bracket is analyzed in detail, the Jacobi identity is verified through a detailed proof, and this proof ensures the Jacobi identity for the Poisson brackets of all the models.

  7. The Nature and Nurture of High IQ: An Extended Sensitive Period for Intellectual Development

    NARCIS (Netherlands)

    Brant, A.M.; Munakata, Y.; Boomsma, D.I.; DeFries, J.C.; Haworth, C.M.A.; Keller, M.C.; Martin, N.G.; McGue, M.; Petrill, S.A.; Plomin, R.; Wadsworth, S.J.; Wright, M.J.; Hewitt, J.K.

    2013-01-01

    IQ predicts many measures of life success, as well as trajectories of brain development. Prolonged cortical thickening observed in individuals with high IQ might reflect an extended period of synaptogenesis and high environmental sensitivity or plasticity. We tested this hypothesis by examining the

  8. Sustainability Attitudes and Behavioral Motivations of College Students: Testing the Extended Parallel Process Model

    Science.gov (United States)

    Perrault, Evan K.; Clark, Scott K.

    2018-01-01

    Purpose: A planet that can no longer sustain life is a frightening thought--and one that is often present in mass media messages. Therefore, this study aims to test the components of a classic fear appeal theory, the extended parallel process model (EPPM) and to determine how well its constructs predict sustainability behavioral intentions. This…

  9. Antioxidants can extend lifespan of Brachionus manjavacas (Rotifera), but only in a few combinations

    Science.gov (United States)

    Fields, Allison M.; Johnston, Rachel K.

    2013-01-01

    Animal cells are protected from oxidative damage by an antioxidant network operating as a coordinated system, with strong synergistic interactions. Lifespan studies with whole animals are expensive and laborious, so there has been little investigation of which antioxidant interactions might be useful for life extension. Animals in the phylum Rotifera are particularly promising models for aging studies because they are small (0.1–1 mm), have short, two-week lifespan, display typical patterns of animal aging, and have well characterized, easy to measure phenotypes of aging and senescence. One class of interventions that has consistently produced significant rotifer life extension is antioxidants. Although the mechanism of antioxidant effects on animal aging remains controversial, the ability of some antioxidant supplements to extend rotifer lifespan was unequivocal. We found that exposing rotifers to certain combinations of antioxidant supplements can produce up to about 20% longer lifespan, but that most antioxidants have no effect. We performed life table tests with 20 single antioxidants and none yielded significant rotifer life extension. We tested 60 two-way combinations of selected antioxidants and only seven (12%) produced significant rotifer life extension. None of the 20 three- and four-way antioxidant combinations tested yielded significant rotifer life extension. These observations suggest that dietary exposure of antioxidants can extend rotifer lifespan, but most antioxidants do not. We observed significant rotifer life extension only when antioxidants were paired with trolox, N-acetyl cysteine, l-carnosine, or EUK-8. This illustrates that antioxidant treatments capable of rotifer life extension are patchily distributed in the parameter space, so large regions must be searched to find them. It furthermore underscores the value of the rotifer model to conduct rapid, facile life table experiments with many treatments, which makes such a search feasible

  10. Market Diffusion of Extended Cycle Hormonal Contraceptives

    Directory of Open Access Journals (Sweden)

    Megen Leeds Schumacher

    2012-01-01

    Full Text Available Background: Extended cycle hormonal contraceptives (e.g. Seasonale, Seasonique when introduced in 2003 were considered a very novel approach to contraception. The idea of manipulating the menstrual cycle so that women would experience just four menstruations a year was radical and was assumed to be responsible for the slow acceptance rate among the general public. Objective: This report analyzes two different aspects of the acceptance of this unique idea in the population. The first was the level of usage of extended cycle hormonal contraceptives in the general population, which was measured by a review of sales figures over time in the United States. The second was an examination of market diffusion as it relates to consumer perceptions regarding the characteristics of these products. Methods: To determine the degree of usage of extended cycle hormonal contraceptives the yearly sales, in terms of units sold, were compared with that of other leading methods of hormonal contraception. Along with the data, survey answers were obtained from 65 women who volunteered to participate in the study. Participants were selected randomly to represent the target population to assess the level of awareness about the benefits, risks, and any other concerns regarding the use of extended cycle hormonal contraceptives. Results: The yearly sales data of units sold showed a definitive increase in the sales of extended cycle hormonal contraceptives since their release on the market. The survey results showed an overwhelming awareness in the study population about the extended regimen. However, only about half of the women in the survey group were aware of its benefits. The main concern reported was the perceived significant side effect profile. Conclusion: Though awareness about the extended cycle hormonal contraception regimen was widespread, the survey population was not well informed about the advantages and the disadvantages regarding the degree of severity of

  11. Extending Symfony 2 web application framework

    CERN Document Server

    Armand, Sébastien

    2014-01-01

    Symfony is a high performance PHP framework for developing MVC web applications. Symfony1 allowed for ease of use but its shortcoming was the difficulty of extending it. However, this difficulty has now been eradicated by the more powerful and extensible Symfony2. Information on more advanced techniques for extending Symfony can be difficult to find, so you need one resource that contains the advanced features in a way you can understand. This tutorial offers solutions to all your Symfony extension problems. You will get to grips with all the extension points that Symfony, Twig, and Doctrine o

  12. Extended Interneuronal Network of the Dentate Gyrus

    Directory of Open Access Journals (Sweden)

    Gergely G. Szabo

    2017-08-01

    Full Text Available Local interneurons control principal cells within individual brain areas, but anecdotal observations indicate that interneuronal axons sometimes extend beyond strict anatomical boundaries. Here, we use the case of the dentate gyrus (DG to show that boundary-crossing interneurons with cell bodies in CA3 and CA1 constitute a numerically significant and diverse population that relays patterns of activity generated within the CA regions back to granule cells. These results reveal the existence of a sophisticated retrograde GABAergic circuit that fundamentally extends the canonical interneuronal network.

  13. Socially extended intentions-in-action

    DEFF Research Database (Denmark)

    Blomberg, Olle

    2011-01-01

    as an unconditional constraint on the contents of intentions-in-action: one may intend to perform a basic action that belongs both to oneself and to another agent. Based on the phenomenology of tool use, I first argue that intentions-in-action of one’s basic actions may be technologically extended, meaning...... that their contents are not restricted to concern the agent’s bodily movements. In analogy with this, I then argue that the phenomenology of some skillful joint activities supports the idea that one’s basic intentions-in-action may be socially extended, in violation of the widely accepted exclusivity constraint...

  14. Focus point supersymmetry in extended gauge mediation

    Energy Technology Data Exchange (ETDEWEB)

    Ding, Ran [School of Physics, Nankai University,Tianjin 300071 (China); Li, Tianjun [State Key Laboratory of Theoretical Physics and Kavli Institute for Theoretical Physics (KITPC),Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing 100190 (China); School of Physical Electronics, University of Electronic Science and Technology of China,Chengdu 610054 (China); Staub, Florian [Bethe Center for Theoretical Physics & Physikalisches Institut der Universität Bonn,Nußallee 12, 53115 Bonn (Germany); Zhu, Bin [School of Physics, Nankai University,Tianjin 300071 (China)

    2014-03-27

    We propose a small extension of the minimal gauge mediation through the combination of extended gauge mediation and conformal sequestering. We show that the focus point supersymmetry can be realized naturally, and the fine tuning is significantly reduced compared to the minimal gauge mediation and extended gauge mediation without focus point. The Higgs boson mass is around 125 GeV, the gauginos remain light, and the gluino is likely to be detected at the next run of the LHC. However, the multi-TeV squarks is out of the reach of the LHC. The numerical calculation for fine-tuning shows that this model remains natural.

  15. Focus point supersymmetry in extended gauge mediation

    International Nuclear Information System (INIS)

    Ding, Ran; Li, Tianjun; Staub, Florian; Zhu, Bin

    2014-01-01

    We propose a small extension of the minimal gauge mediation through the combination of extended gauge mediation and conformal sequestering. We show that the focus point supersymmetry can be realized naturally, and the fine tuning is significantly reduced compared to the minimal gauge mediation and extended gauge mediation without focus point. The Higgs boson mass is around 125 GeV, the gauginos remain light, and the gluino is likely to be detected at the next run of the LHC. However, the multi-TeV squarks is out of the reach of the LHC. The numerical calculation for fine-tuning shows that this model remains natural

  16. Novel Functional Extended Solids at Extreme Conditions

    Science.gov (United States)

    2013-02-01

    distance of 1.9 (±.1) Å. Above 70 GPa, it further transforms into a black 3D fluorite -like structure (Fmmm) of a first observed eight-fold metallic...graphite-like 2D extended phase (Pnnm-2, middle) at 52 GPa, and metallic fluorite -like 3D extended phase (Fmmm, right) at 70 GPa. 4 from that of C...photoluminescence of nanodiamonds, Surface Science 601, 3866 (2007). 16 16. C. Mailhiot, L. H. Yang, and A. K. McMahan, Polymeric nitrogen, Phys. Rev

  17. Alternate Derivation of Geometric Extended Kalman Filter by MEKF Approach

    OpenAIRE

    Chang, Lubin

    2017-01-01

    This note is devoted to deriving the measurement update of the geometric extended Kalman filter using the multiplicative extended Kalman filtering approach, resulting in the attitude estimator referred as geometric multiplicative extended Kalman filter. The equivalence of the derived geometric multiplicative extended Kalman filter and geometric extended Kalman filter is also demonstrated in this note.

  18. Harbour Geotechnics. Book of extended abstracts.

    OpenAIRE

    Kikuchi, Yoshiaki; Pinto, Alexandre; Cerejeira, José

    2016-01-01

    Book of extended abstracts in correspondence to Workshop 2 "Harbour Geotechnics", held in 4th September 2016 at the University of Minho, in Guimarães, Portugal. The event was part of the 3rd ICTG 2016 - International Conference on Transportation Geotechnics (http://www.civil.uminho.pt/3rd-ICTG2016/).

  19. Validating foundry technologies for extended mission profiles

    NARCIS (Netherlands)

    Dijk, K.; Volf, P.; Detcheverry, C.; Yau, A.; Ngan, P.; Liang, Z.; Kuper, F.G.

    2010-01-01

    This paper presents a process qualification and characterization strategy that can extend the foundry process reliability potential to meet specific automotive mission profile requirements. In this case study, data and analyses are provided that lead to sufficient confidence for pushing the allowed

  20. Unsymmetrical extended -conjugated zinc phthalocyanine for ...

    Indian Academy of Sciences (India)

    We have designed and synthesized a new unsymmetrical zinc phthalocyanine based on `push-pull' and extended -conjugation concept, PCH008. The new sensitizer was fully characterized by CHN anlysis, UV-Vis., fluorescence spectroscopies and cyclic voltammetry. The new sensitizer which upon anchoring onto ...

  1. Resonant phenomena in compact and extended systems

    NARCIS (Netherlands)

    Mullen, K.; Loss, D.; Stoof, H.T.C.

    1993-01-01

    We consider the dynamics of Josephson junctions in two formulations: one where the phase is defined on a compact interval [0,2π], and a second where it is defined on an extended interval (-∞,∞). We find that in general the two approaches are not equivalent: they have different sets of allowable

  2. Simulation and analysis of shared extended mind

    NARCIS (Netherlands)

    Bosse, T.; Jonker, C.M.; Schut, M.C.; Treur, J.

    Some types of animals exploit patterns created in the environment as external mental states, thus obtaining an extension of their mind. In the case of social animals the creation and exploitation of such patterns can be shared, which supports a form of shared extended mind or collective

  3. 17. IAEA fusion energy conference. Extended synopses

    International Nuclear Information System (INIS)

    1998-01-01

    Book of extended synopses of the papers, accepted by a international programme committee for presentation at the 17th IAEA Fusion Energy Conference in Yokohama, Japan. The subjects covered are magnetic confinement experiments, plasma heating and current drive, ITER EDA, inertial fusion energy, innovative concepts, fusion technology and theory

  4. Technological Packages Extended To Farmers by Non ...

    African Journals Online (AJOL)

    The paper investigated technological packages extended to farmers by Non Governmental Organizations in the Niger Delta area of Nigeria. Data for the study was collected with the aid of structured questionnaire from 450 respondents in the study area. Findings revealed that yam minisett technology, hybrid cassava ...

  5. Q-Method Extended Kalman Filter

    Science.gov (United States)

    Zanetti, Renato; Ainscough, Thomas; Christian, John; Spanos, Pol D.

    2012-01-01

    A new algorithm is proposed that smoothly integrates non-linear estimation of the attitude quaternion using Davenport s q-method and estimation of non-attitude states through an extended Kalman filter. The new method is compared to a similar existing algorithm showing its similarities and differences. The validity of the proposed approach is confirmed through numerical simulations.

  6. Extending the Agricultural Extension Model. Preliminary Draft.

    Science.gov (United States)

    Rogers, Everett M.; And Others

    The purposes of this report are: to describe the main elements of the U.S. agricultural extension model and its effects on the agricultural revolution; to analyze attempts to extend this model to non-agricultural technology and/or to less developed countries; and to draw general conclusions about the diffusion of technological innovations, with…

  7. Extended plate and beam demonstration home

    Science.gov (United States)

    Patricia Gunderson; Vladimir Kochkin; Xiping Wang

    2018-01-01

    An extended plate and beam (EP&B) design was developed at Home Innovation Research Labs (Upper Marlboro, Maryland) in an effort to provide traditional light-frame wall construction details that are compatible with continuous insulating sheathing. This would encourage wide-spread adoption of high-R walls and promote greater energy efficiency in new houses. The...

  8. The Extended Family and Children's Educational Success

    DEFF Research Database (Denmark)

    Jæger, Mads Meier

    2012-01-01

    characteristics of grandparents and aunts and uncles have few direct effects on educational success, resources in the extended family compensate lacking resources in low-SES families, which in turn promote children’s educational success. The main conclusion is that the total effect of family background...

  9. Extending and embedding the Python interpreter

    NARCIS (Netherlands)

    G. van Rossum (Guido)

    1995-01-01

    textabstractPython is an interpreted, object-oriented programming language. This document describes how to write modules in C or C++ to extend the Python interpreter with new modules. Those modules can define new functions but also new object types and their methods. The document also describes

  10. Extendable linearised adjustment model for deformation analysis

    NARCIS (Netherlands)

    Hiddo Velsink

    2015-01-01

    Author supplied: "This paper gives a linearised adjustment model for the affine, similarity and congruence transformations in 3D that is easily extendable with other parameters to describe deformations. The model considers all coordinates stochastic. Full positive semi-definite covariance matrices

  11. Extendable linearised adjustment model for deformation analysis

    NARCIS (Netherlands)

    Velsink, H.

    2015-01-01

    This paper gives a linearised adjustment model for the affine, similarity and congruence transformations in 3D that is easily extendable with other parameters to describe deformations. The model considers all coordinates stochastic. Full positive semi-definite covariance matrices and correlation

  12. Prevalence and Susceptibility of extended spectrum beta ...

    African Journals Online (AJOL)

    Extended spectrum beta – lactamases (ESBLs) are on the rise in hospital settings across the globe. The presence of ESBLs significantly affects the outcome of an infection and poses a challenge to the management of infection worldwide. Therefore, the aim of the present study is to determine the prevalence and ...

  13. CALL FOR EXTENDED CONCEPT NOTES ECOHEALTH CHAIRS ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Marie-Isabelle Beyer

    CALL FOR EXTENDED CONCEPT NOTES. Page 1 of 1. ECOHEALTH CHAIRS in HEALTH and GLOBAL ENVIRONMENTAL CHANGE in. SUB-SAHARAN AFRICA. Eligible countries. Organizations and researchers based in the eligible country list below can apply as team to this Call. Within limits of. Canadian law and ...

  14. The Extended Mind Thesis and Mechanistic Explanations

    DEFF Research Database (Denmark)

    Fazekas, Peter

    2013-01-01

    The Extended Mind Thesis (EMT) is traditionally formulated against the bedrock of functionalism, and ongoing debates are typically bogged down with questions concerning the exact relationship between EMT and different versions of functionalism. In this paper, I offer a novel ally for EMT: the new...

  15. [Combined hormonal contraception in cycles artificially extended].

    Science.gov (United States)

    Bustillos-Alamilla, Edgardo; Zepeda-Zaragoza, J; Hernández-Ruiz, M A; Briones-Landa, Carlos Humberto

    2010-01-01

    To compare the bleeding patterns, satisfaction and tolerability of 3 different contraceptive in an extended regimens in the service of Family Planning of the North Central Hospital of PEMEX. Healthy, adult women with desire of contraception for one year (N 120) were randomly assigned to receive oral contraceptive drospirenone/ethinyl E2 (group1), the norelgestromin/ethinyl E2 transdermal patch (group 2) and vaginal ring etonogestrel/ ethinyl E2 (group 3) in an extended regimen (42 consecutive days, 1 hormone-free week). Study assessments were conducted at scheduled visits at the time of initial screening, at baseline after 1, 3, 6, and 12 months. Subjects recorded menstrual associated symptoms bleeding data and completed satisfaction questionnaires. Subjects and investigators provided overall assessments of the regimens. Extended use of 3 different contraceptive resulted in fewer bleeding days in every group (66.6%, 55% and 58.3% P 0.0024), and less mastalgia and menstrual pain. Subjects were highly satisfied with three regimens (93.3%, 96.6% and 91.6% P 0.00421). Although not mayor adverse events were reported with this regimen, there was an increase in spotting days; it decreased with each successive cycle of therapy. Efficacy and safety were similar to those reported for traditional cycle. Extended-contraceptive regimen delays menses and reduces bleeding, a profile that may be preferred by women who seek flexibility with their contraceptive method.

  16. Observational constraints on extended Chaplygin gas cosmologies

    Indian Academy of Sciences (India)

    We investigate cosmological models with extended Chaplygin gas (ECG) as a candidate for dark energy and determine the equation of state parameters using observed data namely, observed Hubble data, baryon acousticoscillation data and cosmic microwave background shift data. Cosmological models are investigated ...

  17. Short Communication: Production of extended spectrum beta ...

    African Journals Online (AJOL)

    Multidrug resistant strains of Klebsiella pneumoniae and Escherichia coli constitute a problem in many hospitals. The antibiotic susceptibility profile and the Production of Extended Spetrum Beta-Lactamase (ESBL) of the strains of Klebsiella pneumoniae and Escherichia coli were assessed by the Kirby-Bauer technique and ...

  18. Extended Resin Composite Restorations: Techniques and Procedures

    NARCIS (Netherlands)

    Loomans, B.A.C.; Hilton, T.

    2016-01-01

    This article gives an overview of the state of the art of different restorative treatment procedures and techniques needed for placing extended posterior resin composite restorations. Clinical aspects related to the procedure are discussed and reviewed based on the current literature, such as the

  19. antimicrobial susceptibility pattern of extended spectrum

    African Journals Online (AJOL)

    JAMILU

    ABSTRACT. The emergence of resistant strains of urogenital extended spectrum beta-lactamase producing isolates has presented a serious set back in the treatment option for urogenital tract infection. Emergence and spread of these strains resulted in treatment failure and disease complications. This study was aimed to ...

  20. The inflation sector of extended inflation

    International Nuclear Information System (INIS)

    Kolb, E.W.

    1990-11-01

    In extended inflation the inflationary era is brought to a close by the process of percolation of true vacuum bubbles produced in a first-order phase transition. In this paper I discuss several effects that might obtain if the Universe undergoes an inflationary first-order phase transition. 17 refs

  1. Turbo Codes Extended with Outer BCH Code

    DEFF Research Database (Denmark)

    Andersen, Jakob Dahl

    1996-01-01

    The "error floor" observed in several simulations with the turbo codes is verified by calculation of an upper bound to the bit error rate for the ensemble of all interleavers. Also an easy way to calculate the weight enumerator used in this bound is presented. An extended coding scheme is proposed...

  2. Hamiltonian structure of linearly extended Virasoro algebra

    International Nuclear Information System (INIS)

    Arakelyan, T.A.; Savvidi, G.K.

    1991-01-01

    The Hamiltonian structure of linearly extended Virasoro algebra which admits free bosonic field representation is described. An example of a non-trivial extension is found. The hierarchy of integrable non-linear equations corresponding to this Hamiltonian structure is constructed. This hierarchy admits the Lax representation by matrix Lax operator of second order

  3. Consistent spectroscopy for a extended gauge model

    International Nuclear Information System (INIS)

    Oliveira Neto, G. de.

    1990-11-01

    The consistent spectroscopy was obtained with a Lagrangian constructed with vector fields with a U(1) group extended symmetry. As consistent spectroscopy is understood the determination of quantum physical properties described by the model in an manner independent from the possible parametrizations adopted in their description. (L.C.J.A.)

  4. Diagrammar in an extended theory of gravity

    Science.gov (United States)

    Dunbar, David C.; Godwin, John H.; Jehu, Guy R.; Perkins, Warren B.

    2017-08-01

    We show how the S-matrix of an extended theory of gravity defined by its three-point amplitudes can be constructed by demanding factorisation. The resultant S-matrix has tree amplitudes obeying the same soft singularity theorems as Einstein gravity including the sub-sub-leading terms.

  5. Features of the extended-release metformin

    Directory of Open Access Journals (Sweden)

    T O Yalochkina

    2013-03-01

    Full Text Available Реферат по материалам статьи Ali S, Fonseca V. Overview of metformin: special focus on metformin extended release. Expert Opin Pharmacother. 2012 Aug;13(12:1797-805.

  6. Venus: No Breaks from an Extended Childhood

    Science.gov (United States)

    Moore, W. B.; Kankanamge, D. G. J.

    2017-05-01

    High surface temperatures lead to lower heat flow and lower stress as planets transition out of the heat-pipe mode into subsolidus convection. This causes Venus to miss the window for plate tectonics due to an extended heat-pipe childhood.

  7. Extending the Multi Regional Input-Output framework to labor related impacts: a proof of concept

    DEFF Research Database (Denmark)

    Hardadi, Gilang; Pizzol, Massimo

    2017-01-01

    -O framework to social impacts. These challenges are addressed in this study where the Exiobase database was extended with new data on five quantitative indicators available from the International Labor Organization: employment; working hours; salary; occupational accident cases; and unemployment......-being measured in quality-adjusted life years was then performed. The results show an appreciable match between the databases, with justifiable interpolations for missing countries. The study demonstrates how to obtain an open and quantitative I-O database extended with indicators on labor-related impacts......Given the high potential shown by the recent developments in environmentally extended and multiregional input-output (I-O) analysis, a natural step would be to extend this theoretical framework beyond the environmental dimension to include the social dimension, in line with parallel advancements...

  8. Extended KN algebras and extended conformal field theories over higher genus Riemann surfaces

    International Nuclear Information System (INIS)

    Ceresole, A.; Huang Chaoshang

    1990-01-01

    A global operator formalism for extended conformal field theories over higher genus Riemann surfaces is introduced and extended KN algebra are obtained by means of the KN bases. The BBSS construction of the spin-3 operator is carried out for Kac-Moody algebra A 2 over a Riemann surface of arbitrary genus. (orig.)

  9. Elaborated Odor Test for Extended Exposure

    Science.gov (United States)

    Buchanan, Vanessa D.; Henry, Emily J.; Mast, Dion J.; Harper, Susana A.; Beeson, Harold D.; Tapia, Alma S.

    2016-01-01

    Concerns were raised when incidental exposure to a proprietary bonding material revealed the material had an irritating odor. The NASA-STD-6001B document describes a supplemental test method option for programs to evaluate materials with odor concerns (Test 6, Odor Assessment). In addition to the supplemental standard odor assessment with less than 10 seconds of exposure, the NASA White Sands Test Facility (WSTF) Materials Flight Acceptance Testing section was requested to perform an odor test with an extended duration to evaluate effects of an extended exposure and to more closely simulate realistic exposure scenarios. With approval from the NASA Johnson Space Center Industrial Hygienist, WSTF developed a 15-minute odor test method. WSTF performed this extended-duration odor test to evaluate the odor and physical effects of the bonding material configured between two aluminum plates, after the safety of the gas was verified via toxicity analysis per NASA-STD-6001B Test 7, Determination of Offgassed Products. During extended-duration testing, odor panel members were arranged near the test material in a small room with the air handlers and doors closed to minimize dilution. The odor panel members wafted gas toward themselves and recorded their individual assessments of odor and physical effects at various intervals during the 15-minute exposure and posttest. A posttest interview was conducted to obtain further information. Testing was effective in providing data for comparison and selection of an optimal offgassing and odor containment configuration. The developed test method for extended exposure is proposed as a useful tool for further evaluating materials with identified odors of concern if continued use of the material is anticipated.

  10. Extended anticoagulation in venous thromboembolism disease. In favour.

    Science.gov (United States)

    Fernández Capitan, M C

    Venous thromboembolism disease can be considered a chronic disease because, after the first episode, there is a life-long risk of recurrence. Recurrence is a severe complication. Anticoagulation is effective while it is maintained, but when it is discontinued, the risk of new thrombotic events persists indefinitely. Clinical practice guidelines offer specific recommendations on the treatment duration for patients with provoked or recurrent disease but are not specific for those with a first unprovoked episode. The decision should be made after a careful individual assessment of the risk-benefit of anticoagulation. This article reviews the evidence in favour of extending the anticoagulation and the current therapeutic options. Copyright © 2017. Publicado por Elsevier España, S.L.U.

  11. [Extended hemoperfusion in the treatment of acute carbamazepine intoxication].

    Science.gov (United States)

    Peces, R; Azorín, S; Peces, C; Selgas, R

    2010-01-01

    Carbamazepine is used in the treatment of epilepsy, and also prescribed in neuralgic pain syndromes, and certain affective disorders. Carbamazepine intoxication with suicide attempt is a relatively common clinical problem that can result in coma, respiratory depression, arrhythmia, hemodynamic instability and death. The drug's relatively high molecular weight, elevated volume of distribution and intense protein-binding render it difficult to extracorporeal removal, but published experience with hemoperfusion or hemodialysis present variable results. We describe a case report involving carbamazepine intoxication who was successfully treated with charcoal hemoperfusion. With this treatment the half-life of carbamazepine was reduced with rapid lowering of carbamazepine levels and clinical improvement. Based on our experience in this patient and a review of previously reported cases, extended charcoal hemoperfusion should be considered for serious carbamazepine intoxication because free as well as bound drug fractions are eliminated via this technique.

  12. Recognising life

    DEFF Research Database (Denmark)

    Nissen, Morten

    2013-01-01

    ’ – that the contemporary discursive pragmatics of more or less pharmaceutical life practices still include forms of transcendence – and by the wish to fertilize the field of bio-politics with the indexical inter-subjectivity of the concept of ideology, as derived from an antiessentialist reading of Hegelian......–Marxist traditions. The analysis unfolds as an ideology critique that reconstructs, and seeks ways to overcome, particular forms of recognition that are identifiable in the data and in the field of drug practices, and how these form part of the constitution of singular collectives and participants – in these life...

  13. Buffering the pH of the culture medium does not extend yeast replicative lifespan.

    Science.gov (United States)

    Wasko, Brian M; Carr, Daniel T; Tung, Herman; Doan, Ha; Schurman, Nathan; Neault, Jillian R; Feng, Joey; Lee, Janet; Zipkin, Ben; Mouser, Jacob; Oudanonh, Edward; Nguyen, Tina; Stetina, Torin; Shemorry, Anna; Lemma, Mekedes; Kaeberlein, Matt

    2013-01-01

    During chronological aging of budding yeast cells, the culture medium can become acidified, and this acidification limits cell survival.  As a consequence, buffering the culture medium to pH 6 significantly extends chronological life span under standard conditions in synthetic medium.  In this study, we assessed whether a similar process occurs during replicative aging of yeast cells.  We find no evidence that buffering the pH of the culture medium to pH levels either higher or lower than the initial pH of the medium is able to significantly extend replicative lifespan.  Thus, we conclude that, unlike chronological life span, replicative life span is not limited by acidification of the culture medium or by changes in the pH of the environment.

  14. Range-extending Zinc-air battery for electric vehicle

    Directory of Open Access Journals (Sweden)

    Steven B. Sherman

    2018-01-01

    Full Text Available A vehicle model is used to evaluate a novel powertrain that is comprised of a dual energy storage system (Dual ESS. The system includes two battery packs with different chemistries and the necessary electronic controls to facilitate their coordination and optimization. Here, a lithium-ion battery pack is used as the primary pack and a Zinc-air battery as the secondary or range-extending pack. Zinc-air batteries are usually considered unsuitable for use in vehicles due to their poor cycle life, but the model demonstrates the feasibility of this technology with an appropriate control strategy, with limited cycling of the range extender pack. The battery pack sizes and the battery control strategy are configured to optimize range, cost and longevity. In simulation the vehicle performance compares favourably to a similar vehicle with a single energy storage system (Single ESS powertrain, travelling up to 75 km further under test conditions. The simulation demonstrates that the Zinc-air battery pack need only cycle 100 times to enjoy a ten-year lifespan. The Zinc-air battery model is based on leading Zinc-air battery research from literature, with some assumptions regarding achievable improvements. Having such a model clarifies the performance requirements of Zinc-air cells and improves the research community's ability to set performance targets for Zinc-air cells.

  15. Optimizing Extender Code for NCSX Analyses

    International Nuclear Information System (INIS)

    Richman, M.; Ethier, S.; Pomphrey, N.

    2008-01-01

    Extender is a parallel C++ code for calculating the magnetic field in the vacuum region of a stellarator. The code was optimized for speed and augmented with tools to maintain a specialized NetCDF database. Two parallel algorithms were examined. An even-block work-distribution scheme was comparable in performance to a master-slave scheme. Large speedup factors were achieved by representing the plasma surface with a spline rather than Fourier series. The accuracy of this representation and the resulting calculations relied on the density of the spline mesh. The Fortran 90 module db access was written to make it easy to store Extender output in a manageable database. New or updated data can be added to existing databases. A generalized PBS job script handles the generation of a database from scratch

  16. Extended Target Recognition in Cognitive Radar Networks

    Directory of Open Access Journals (Sweden)

    Xiqin Wang

    2010-11-01

    Full Text Available We address the problem of adaptive waveform design for extended target recognition in cognitive radar networks. A closed-loop active target recognition radar system is extended to the case of a centralized cognitive radar network, in which a generalized likelihood ratio (GLR based sequential hypothesis testing (SHT framework is employed. Using Doppler velocities measured by multiple radars, the target aspect angle for each radar is calculated. The joint probability of each target hypothesis is then updated using observations from different radar line of sights (LOS. Based on these probabilities, a minimum correlation algorithm is proposed to adaptively design the transmit waveform for each radar in an amplitude fluctuation situation. Simulation results demonstrate performance improvements due to the cognitive radar network and adaptive waveform design. Our minimum correlation algorithm outperforms the eigen-waveform solution and other non-cognitive waveform design approaches.

  17. Junction conditions in extended Teleparallel gravities

    Energy Technology Data Exchange (ETDEWEB)

    De la Cruz-Dombriz, Álvaro [Departamento de Física Teórica I, Ciudad Universitaria, Universidad Complutense de Madrid, E-28040 Madrid (Spain); Dunsby, Peter K.S.; Sáez-Gómez, Diego, E-mail: dombriz@fis.ucm.es, E-mail: peter.dunsby@uct.ac.za, E-mail: diego.saezgomez@uct.ac.za [Astrophysics, Cosmology and Gravity Centre (ACGC), Department of Mathematics and Applied Mathematics, University of Cape Town, Rondebosch 7701, Cape Town (South Africa)

    2014-12-01

    In the context of extended Teleparallel gravity theories, we address the issue of junction conditions required to guarantee the correct matching of different regions of spacetime. In the absence of shells/branes, these conditions turn out to be more restrictive than their counterparts in General Relativity as in other extended theories of gravity. In fact, the general junction conditions on the matching hypersurfaces depend on the underlying theory and a new condition on the induced tetrads in order to avoid delta-like distributions in the field equations. This result imposes strict consequences on the viability of standard solutions such as the Einstein-Straus-like construction. We find that the continuity of the scalar torsion is required in order to recover the usual General Relativity results.

  18. Extending applicability of bimetric theory: chameleon bigravity

    Science.gov (United States)

    De Felice, Antonio; Mukohyama, Shinji; Uzan, Jean-Philippe

    2018-02-01

    This article extends bimetric formulations of massive gravity to make the mass of the graviton to depend on its environment. This minimal extension offers a novel way to reconcile massive gravity with local tests of general relativity without invoking the Vainshtein mechanism. On cosmological scales, it is argued that the model is stable and that it circumvents the Higuchi bound, hence relaxing the constraints on the parameter space. Moreover, with this extension the strong coupling scale is also environmentally dependent in such a way that it is kept sufficiently higher than the expansion rate all the way up to the very early universe, while the present graviton mass is low enough to be phenomenologically interesting. In this sense the extended bigravity theory serves as a partial UV completion of the standard bigravity theory. This extension is very generic and robust and a simple specific example is described.

  19. Does string theory lead to extended inflation?

    Science.gov (United States)

    Campbell, Bruce A.; Linde, Andrei; Olive, Keith A.

    1991-05-01

    We consider the relationship between string theory and currently proposed models of extended inflation. In doing so, we discuss the conformal actions in string theory and in Jordan-Brans-Dicke gravity. We show explicitly the equivalence of pictures in which either gauge or gravitational couplings are changing with time. We demonstrate that the existence of the dilation in string theory does not naturally lead to extended inflation as currently discussed. We also discuss the resolution of the graceful exit problem of old inflation in Einstein gravity using either power-law inflation, or exponential inflation with a changing bubble formation rate. On leave of absence from School of Physics and Astronomy, University of Minnesota, Minneapolis, MN 55455, USA.

  20. Extended Josephson Relation and Abrikosov lattice deformation

    International Nuclear Information System (INIS)

    Matlock, Peter

    2012-01-01

    From the point of view of time-dependent Ginzburg Landau (TDGL) theory, a Josephson-like relation is derived for an Abrikosov vortex lattice accelerated and deformed by applied fields. Beginning with a review of the Josephson Relation derived from the two ingredients of a lattice-kinematics assumption in TDGL theory and gauge invariance, we extend the construction to accommodate a time-dependent applied magnetic field, a Floating-Kernel formulation of normal current, and finally lattice deformation due to the electric field and inertial effects of vortex-lattice motion. The resulting Josephson-like relation, which we call an Extended Josephson Relation, applies to a much wider set of experimental conditions than the original Josephson Relation, and is explicitly compatible with the considerations of TDGL theory.

  1. Application of electron closures in extended MHD

    Science.gov (United States)

    Held, Eric; Adair, Brett; Taylor, Trevor

    2017-10-01

    Rigorous closure of the extended MHD equations in plasma fluid codes includes the effects of electron heat conduction along perturbed magnetic fields and contributions of the electron collisional friction and stress to the extended Ohms law. In this work we discuss application of a continuum numerical solution to the Chapman-Enskog-like electron drift kinetic equation using the NIMROD code. The implementation is a tightly-coupled fluid/kinetic system that carefully addresses time-centering in the advance of the fluid variables with their kinetically-computed closures. Comparisons of spatial accuracy, computational efficiency and required velocity space resolution are presented for applications involving growing magnetic islands in cylindrical and toroidal geometry. The reduction in parallel heat conduction due to particle trapping in toroidal geometry is emphasized. Work supported by DOE under Grant Nos. DE-FC02-08ER54973 and DE-FG02-04ER54746.

  2. Optimizing Extender Code for NCSX Analyses

    Energy Technology Data Exchange (ETDEWEB)

    M. Richman, S. Ethier, and N. Pomphrey

    2008-01-22

    Extender is a parallel C++ code for calculating the magnetic field in the vacuum region of a stellarator. The code was optimized for speed and augmented with tools to maintain a specialized NetCDF database. Two parallel algorithms were examined. An even-block work-distribution scheme was comparable in performance to a master-slave scheme. Large speedup factors were achieved by representing the plasma surface with a spline rather than Fourier series. The accuracy of this representation and the resulting calculations relied on the density of the spline mesh. The Fortran 90 module db access was written to make it easy to store Extender output in a manageable database. New or updated data can be added to existing databases. A generalized PBS job script handles the generation of a database from scratch

  3. Extended Deterministic Mean-Field Games

    KAUST Repository

    Gomes, Diogo A.

    2016-04-21

    In this paper, we consider mean-field games where the interaction of each player with the mean field takes into account not only the states of the players but also their collective behavior. To do so, we develop a random variable framework that is particularly convenient for these problems. We prove an existence result for extended mean-field games and establish uniqueness conditions. In the last section, we consider the Master Equation and discuss properties of its solutions.

  4. Extended obstruction tensors and renormalized volume coefficients

    OpenAIRE

    Graham, C. Robin

    2009-01-01

    The behavior under conformal change of the renormalized volume coefficients associated to a pseudo-Riemannian metric is investigated. It is shown that they define second order fully nonlinear operators in the conformal factor whose algebraic structure is elucidated via the introduction of "extended obstruction tensors". These together with the Schouten tensor constitute building blocks for the coefficients in the ambient metric expansion. The renormalized volume coefficients have recently bee...

  5. An extended Henon-Heiles system

    International Nuclear Information System (INIS)

    Hone, A.N.W.; Novikov, V.; Verhoeven, C.

    2008-01-01

    We consider an integrable system of partial differential equations possessing a Lax pair with an energy-dependent Lax operator of second order, of the type described by Antonowicz and Fordy. By taking the travelling wave reduction of this system we show that the integrable case (ii) Henon-Heiles system can be extended by adding an arbitrary number of non-polynomial (rational) terms to the potential

  6. The renewable tradition (extended play remix

    Directory of Open Access Journals (Sweden)

    Mark Amerika

    2009-12-01

    Full Text Available Drawing from a network of appropriation artists, process philosophers, performance poets, pla(ygiarists, and other remix provocateurs, this experimental artist essay investigates the act of remixologically inhabiting the body language of others and, in the process, devises an aesthetic theory that situates the contemporary artist as a "postproduction medium" whose methodologies further extend avant-garde practice into the 21st century.

  7. Behaviour of the extended Toda lattice

    Science.gov (United States)

    Wattis, Jonathan A. D.; Gordoa, Pilar R.; Pickering, Andrew

    2015-11-01

    We consider the first member of an extended Toda lattice hierarchy. This system of equations is differential with respect to one independent variable and differential-delay with respect to a second independent variable. We use asymptotic analysis to consider the long wavelength limits of the system. By considering various magnitudes for the parameters involved, we derive reduced equations related to the Korteweg-de Vries and potential Boussinesq equations.

  8. Lepton flavor violation in an extended MSSM

    CERN Document Server

    Espinosa-Castañeda, R.; Gómez-Bock, M.; Mondragón, M.

    2016-01-01

    In this work we explore a lepton flavor violation effect induced at one loop for a flavor structure in an extended minimal standard supersymmetric model, considering an ansatz for the trilinear term. In particular we find a finite expression which will show the impact of this phenomena in the $h\\to \\mu \\tau$ decay, produced by a mixing in the trilinear coupling of the soft supersymmetric Lagrangian.

  9. Deterministic automata for extended regular expressions

    Directory of Open Access Journals (Sweden)

    Syzdykov Mirzakhmet

    2017-12-01

    Full Text Available In this work we present the algorithms to produce deterministic finite automaton (DFA for extended operators in regular expressions like intersection, subtraction and complement. The method like “overriding” of the source NFA(NFA not defined with subset construction rules is used. The past work described only the algorithm for AND-operator (or intersection of regular languages; in this paper the construction for the MINUS-operator (and complement is shown.

  10. Why an extended evolutionary synthesis is necessary.

    Science.gov (United States)

    Müller, Gerd B

    2017-10-06

    Since the last major theoretical integration in evolutionary biology-the modern synthesis (MS) of the 1940s-the biosciences have made significant advances. The rise of molecular biology and evolutionary developmental biology, the recognition of ecological development, niche construction and multiple inheritance systems, the '-omics' revolution and the science of systems biology, among other developments, have provided a wealth of new knowledge about the factors responsible for evolutionary change. Some of these results are in agreement with the standard theory and others reveal different properties of the evolutionary process. A renewed and extended theoretical synthesis, advocated by several authors in this issue, aims to unite pertinent concepts that emerge from the novel fields with elements of the standard theory. The resulting theoretical framework differs from the latter in its core logic and predictive capacities. Whereas the MS theory and its various amendments concentrate on genetic and adaptive variation in populations, the extended framework emphasizes the role of constructive processes, ecological interactions and systems dynamics in the evolution of organismal complexity as well as its social and cultural conditions. Single-level and unilinear causation is replaced by multilevel and reciprocal causation. Among other consequences, the extended framework overcomes many of the limitations of traditional gene-centric explanation and entails a revised understanding of the role of natural selection in the evolutionary process. All these features stimulate research into new areas of evolutionary biology.

  11. Thermodynamic volume and the extended Smarr relation

    Energy Technology Data Exchange (ETDEWEB)

    Hyun, Seungjoon; Jeong, Jaehoon; Park, Sang-A; Yi, Sang-Heon [Department of Physics, College of Science, Yonsei University,Seoul 120-749 (Korea, Republic of)

    2017-04-10

    We continue to explore the scaling transformation in the reduced action formalism of gravity models. As an extension of our construction, we consider the extended forms of the Smarr relation for various black holes, adopting the cosmological constant as the bulk pressure as in some literatures on black holes. Firstly, by using the quasi-local formalism for charges, we show that, in a general theory of gravity, the volume in the black hole thermodynamics could be defined as the thermodynamic conjugate variable to the bulk pressure in such a way that the first law can be extended consistently. This, so called, thermodynamic volume can be expressed explicitly in terms of the metric and field variables. Then, by using the scaling transformation allowed in the reduced action formulation, we obtain the extended Smarr relation involving the bulk pressure and the thermodynamic volume. In our approach, we do not resort to Euler’s homogeneous scaling of charges while incorporating the would-be hairy contribution without any difficulty.

  12. Origin of density fluctuations in extended inflation

    International Nuclear Information System (INIS)

    Kolb, E.W.; Salopek, D.S.; Turner, M.S.

    1990-01-01

    We calculate both the curvature and isocurvature density fluctuations that arise due to quantum fluctuations in a simple model of extended inflation based upon the Jordan-Brans-Dicke theory. The curvature fluctuations that arise due to quantum fluctuations in the Brans-Dicke field in general have a non-scale-invariant spectrum and an amplitude that is cosmologically acceptable and interesting without having to tune any coupling constant to a very small value. The curvature perturbations that arise due to the Higgs field are subdominant. If there are other massless fields in the theory, e.g., an axion or an ilion, then isocurvature fluctuations arise in these fields too. Production of gravitational waves and the massless particles associated with excitations of the Brans-Dicke field are also discussed. Several attempts at more realistic models of extended inflation are also analyzed. The importance of the Einstein conformal frame in calculating curvature fluctuations is emphasized. When viewed in this frame, extended inflation closely resembles slow-rollover inflation with an exponential potential, and the usual formula for the amplitude of curvature perturbations applies directly

  13. Origin of density fluctuations in extended inflation

    International Nuclear Information System (INIS)

    Kolb, E.W.; Salopek, D.S.; Turner, M.S.

    1990-05-01

    The density fluctuations (both curvature and isocurvature) that arise due to quantum fluctuations in a simple model of extended inflation based upon the Jordan-Brans-Dicke theory are calculated. Curvature fluctuations arise due to quantum fluctuations in the Brans-Dicke field, in general have a nonscale-invariant spectrum, and can have an amplitude that is cosmologically acceptable and interesting without having to tune any coupling constant to a very small value. The density perturbations that arise due to the inflation field are subdominant. If there are other massless fields in the theory, e.g., an axion or an ilion, then isocurvature fluctuations arise in these fields too. Production of gravitational waves and the massless particles associated with excitations of the Brans-Dicke field are also discussed. Several attempts at more realistic models of extended inflation are also analyzed. The importance of the Einstein conformal frame in calculating curvature fluctuations is emphasized. When viewed in this frame, extended inflation closely resembles slow-rollover inflation with an exponential potential and the usual formula for the amplitude of curvature perturbations applies

  14. Life Extension of Aging High Level Waste (HLW) Tanks

    International Nuclear Information System (INIS)

    The Double Shell Tanks (DSTs) play a critical role in the Hanford High-Level Waste Treatment Complex, and therefore activities are underway to protect and better understand these tanks. The DST Life Extension Program is focused on both tank life extension and on evaluation of tank integrity. Tank life extension activities focus on understanding tank failure modes and have produced key chemistry and operations controls to minimize tank corrosion and extend useful tank life. Tank integrity program activities have developed and applied key technologies to evaluate the condition of the tank structure and predict useful tank life. Program results to date indicate that DST useful life can be extended well beyond the original design life and allow the existing tanks to fill a critical function within the Hanford High-Level Waste Treatment Complex. In addition the tank life may now be more reliably predicted, facilitating improved planning for the use and possible future replacement of these tanks

  15. Tapentadol extended release for the management of chronic neck pain

    Science.gov (United States)

    Billeci, Domenico; Coluzzi, Flaminia

    2017-01-01

    Background The role of opioids in the management of chronic neck pain is still poorly investigated. No data are available on tapentadol extended release (ER). In this article, we present 54 patients with moderate-to-severe chronic neck pain treated with tapentadol ER. Patients and methods Patients received tapentadol ER 100 mg/day; dosage was then adjusted according to clinical needs. The following parameters were recorded: pain; Douleur Neuropathique 4 score; Neck Disability Index score; range of motion; pain-associated sleep interference; quality of life (Short Form [36] Health Survey); Patient Global Impression of Change (PGIC); Clinician GIC; opioid-related adverse effects; and need for other analgesics. Results A total of 44 of 54 patients completed the 12-week observation. Tapentadol ER daily doses increased from 100 mg/day to a mean (standard deviation) dosage of 204.5 (102.8) mg/day at the final evaluation. Mean pain intensity at movement significantly decreased from baseline (8.1 [1.1]) to all time points (PNeck Disability Index scores from 55.6 (18.6) at baseline to 19.7 (20.9) at the final evaluation (Pneck range of motion in all three planes of motion, particularly in lateral flexion. Quality of life significantly improved in all Short Form (36) Health Survey subscales (Pneck pain, including opioid-naïve subjects. Patients can expect a decrease in pain, an improvement in neck function, and a decrease in neuropathic symptoms. PMID:28280384

  16. Extending healthy ageing: nutrient sensitive pathway and centenarian population

    Directory of Open Access Journals (Sweden)

    Davinelli Sergio

    2012-04-01

    Full Text Available Abstract Ageing is a challenge for any living organism and human longevity is a complex phenotype. With increasing life expectancy, maintaining long-term health, functionality and well-being during ageing has become an essential goal. To increase our understanding of how ageing works, it may be advantageous to analyze the phenotype of centenarians, perhaps one of the best examples of successful ageing. Healthy ageing involves the interaction between genes, the environment, and lifestyle factors, particularly diet. Besides evaluating specific gene-environment interactions in relation to exceptional longevity, it is important to focus attention on modifiable lifestyle factors such as diet and nutrition to achieve extension of health span. Furthermore, a better understanding of human longevity may assist in the design of strategies to extend the duration of optimal human health. In this article we briefly discuss relevant topics on ageing and longevity with particular focus on dietary patterns of centenarians and nutrient-sensing pathways that have a pivotal role in the regulation of life span. Finally, we also discuss the potential role of Nrf2 system in the pro-ageing signaling emphasizing its phytohormetic activation.

  17. One life

    Directory of Open Access Journals (Sweden)

    Demkova E.E.

    2016-06-01

    Full Text Available It is not easy to care for a special needs child. Especially, it is easy to understand parents’ worries about their grown up children. Living in one’s own family or supported living in the community are much more preferable than the options the state can offer. The author — a mother of a young woman with autism — contemplates about possibilities for independent living for a person with special needs after their parents are gone. She is confident that teaching a child skills for independent living is not less important than giving them school education. The author illustrates her thoughts with real examples of support for adults with disabilities in their independent life or life in a foster family in a city, as well in rural areas.

  18. Pirate Life

    OpenAIRE

    Slaman, Matthew

    2017-01-01

    The current work project was brought forth in order to understand and measure the performance/success of an entrepreneurial venture, Pirate Life: Children’s Theatre in Toronto, Canada. The Balance Score Card (BSC) was selected as the appropriate tool for this analysis to simply end effectively outline the major streams of the organization and organize them in a manner that would demonstrate success and areas needing improvement – providing the management with a calibration tool...

  19. Nanostructured Humidity Sensor for Spacecraft Life Support Systems, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Humidity is a critical variable for monitoring and control on extended duration missions because it can affect the operation and efficiency of closed loop life...

  20. Life cycle management in product development

    DEFF Research Database (Denmark)

    Skelton, Kristen; Pattis, Anna

    2013-01-01

    The integration of Life Cycle Thinking (LCT) and Life Cycle Management (LCM) into business operations poses great challenges, as it requires a wider range of environmental responsibility often extending beyond a company's immediate control. Simultaneously, it offers many opportunities...... in the innovation and design phases. This comparative analysis explores the various approaches and challenges two companies are currently facing in their attempts to integrate LCT into their core product development processes....