An Empirical Study of Parameter Estimation for Stated Preference Experimental Design
Directory of Open Access Journals (Sweden)
Fei Yang
2014-01-01
Full Text Available The stated preference experimental design can affect the reliability of the parameters estimation in discrete choice model. Some scholars have proposed some new experimental designs, such as D-efficient, Bayesian D-efficient. But insufficient empirical research has been conducted on the effectiveness of these new designs and there has been little comparative analysis of the new designs against the traditional designs. In this paper, a new metro connecting Chengdu and its satellite cities is taken as the research subject to demonstrate the validity of the D-efficient and Bayesian D-efficient design. Comparisons between these new designs and orthogonal design were made by the fit of model and standard deviation of parameters estimation; then the best model result is obtained to analyze the travel choice behavior. The results indicate that Bayesian D-efficient design works better than D-efficient design. Some of the variables can affect significantly the choice behavior of people, including the waiting time and arrival time. The D-efficient and Bayesian D-efficient design for MNL can acquire reliability result in ML model, but the ML model cannot develop the theory advantages of these two designs. Finally, the metro can handle over 40% passengers flow if the metro will be operated in the future.
International Nuclear Information System (INIS)
Delforge, J.; Syrota, A.; Mazoyer, B.M.
1989-01-01
General framework and various criteria for experimental design optimisation are presented. The methodology is applied to estimation of receptor-ligand reaction model parameters with dynamic positron emission tomography data. The possibility of improving parameter estimation using a new experimental design combining an injection of the β + -labelled ligand and an injection of the cold ligand is investigated. Numerical simulations predict remarkable improvement in the accuracy of parameter estimates with this new experimental design and particularly the possibility of separate estimations of the association constant (k +1 ) and of receptor density (B' max ) in a single experiment. Simulation predictions are validated using experimental PET data in which parameter uncertainties are reduced by factors ranging from 17 to 1000. (author)
International Nuclear Information System (INIS)
Volkman, Y.
1980-07-01
The optimal design of experimental separation processes for maximum accuracy in the estimation of process parameters is discussed. The sensitivity factor correlates the inaccuracy of the analytical methods with the inaccuracy of the estimation of the enrichment ratio. It is minimized according to the design parameters of the experiment and the characteristics of the analytical method
Wagner, Brian J.; Harvey, Judson W.
1997-01-01
Tracer experiments are valuable tools for analyzing the transport characteristics of streams and their interactions with shallow groundwater. The focus of this work is the design of tracer studies in high-gradient stream systems subject to advection, dispersion, groundwater inflow, and exchange between the active channel and zones in surface or subsurface water where flow is stagnant or slow moving. We present a methodology for (1) evaluating and comparing alternative stream tracer experiment designs and (2) identifying those combinations of stream transport properties that pose limitations to parameter estimation and therefore a challenge to tracer test design. The methodology uses the concept of global parameter uncertainty analysis, which couples solute transport simulation with parameter uncertainty analysis in a Monte Carlo framework. Two general conclusions resulted from this work. First, the solute injection and sampling strategy has an important effect on the reliability of transport parameter estimates. We found that constant injection with sampling through concentration rise, plateau, and fall provided considerably more reliable parameter estimates than a pulse injection across the spectrum of transport scenarios likely encountered in high-gradient streams. Second, for a given tracer test design, the uncertainties in mass transfer and storage-zone parameter estimates are strongly dependent on the experimental Damkohler number, DaI, which is a dimensionless combination of the rates of exchange between the stream and storage zones, the stream-water velocity, and the stream reach length of the experiment. Parameter uncertainties are lowest at DaI values on the order of 1.0. When DaI values are much less than 1.0 (owing to high velocity, long exchange timescale, and/or short reach length), parameter uncertainties are high because only a small amount of tracer interacts with storage zones in the reach. For the opposite conditions (DaI ≫ 1.0), solute
Design Parameters of Vortex Pumps: A Meta-Analysis of Experimental Studies
Directory of Open Access Journals (Sweden)
Angela Gerlach
2017-01-01
Full Text Available Vortex pumps can impel solid-containing fluids and are therefore widely applied, from wastewater transport to the food industry. Despite constant efforts to improve vortex pumps, however, they have remained relatively inefficient compared to conventional centrifugal pumps. To find an optimized design of vortex pumps, this paper provides a systematic analysis on experimental studies that investigated how variations in geometric parameters influence vortex pump characteristics, in particular the pump head, the pressure coefficient and the efficiency for best point operation. To this end, an extensive literature search was conducted, and eighteen articles with 53 primary investigations were identified and meta-integrated. This showed that it is not yet clarified how vortex pumps operate. Two different assumptions of the underlying operating principle of a vortex pump lead to diverging design principles. From the results of this meta-analysis, we deduce recommendations for a more efficient design of a vortex pump and emphasize further aspects on the underlying operating principle of a vortex pump.
Song, Xingliang; Sha, Pengfei; Fan, Yuanyuan; Jiang, R.; Zhao, Jiangshan; Zhou, Yi; Yang, Junhong; Xiong, Guangliang; Wang, Yu
2018-02-01
Due to complex kinetics of formation and loss mechanisms, such as ion-ion recombination reaction, neutral species harpoon reaction, excited state quenching and photon absorption, as well as their interactions, the performance behavior of different laser gas medium parameters for excimer laser varies greatly. Therefore, the effects of gas composition and total gas pressure on excimer laser performance attract continual research studies. In this work, orthogonal experimental design (OED) is used to investigate quantitative and qualitative correlations between output laser energy characteristics and gas medium parameters for an ArF excimer laser with plano-plano optical resonator operation. Optimized output laser energy with good pulse to pulse stability can be obtained effectively by proper selection of the gas medium parameters, which makes the most of the ArF excimer laser device. Simple and efficient method for gas medium optimization is proposed and demonstrated experimentally, which provides a global and systematic solution. By detailed statistical analysis, the significance sequence of relevant parameter factors and the optimized composition for gas medium parameters are obtained. Compared with conventional route of varying single gas parameter factor sequentially, this paper presents a more comprehensive way of considering multivariables simultaneously, which seems promising in striking an appropriate balance among various complicated parameters for power scaling study of an excimer laser.
Gmar, Soumaya; Helali, Nawel; Boubakri, Ali; Sayadi, Ilhem Ben Salah; Tlili, Mohamed; Amor, Mohamed Ben
2017-12-01
The aim of this work is to study the desalination of brackish water by electrodialysis (ED). A two level-three factor (23) full factorial design methodology was used to investigate the influence of different physicochemical parameters on the demineralization rate (DR) and the specific power consumption (SPC). Statistical design determines factors which have the important effects on ED performance and studies all interactions between the considered parameters. Three significant factors were used including applied potential, salt concentration and flow rate. The experimental results and statistical analysis show that applied potential and salt concentration are the main effect for DR as well as for SPC. The effect of interaction between applied potential and salt concentration was observed for SPC. A maximum value of 82.24% was obtained for DR under optimum conditions and the best value of SPC obtained was 5.64 Wh L-1. Empirical regression models were also obtained and used to predict the DR and the SPC profiles with satisfactory results. The process was applied for the treatment of real brackish water using the optimal parameters.
International Nuclear Information System (INIS)
Hanra, M.S.; Verma, R.K.; Ramani, M.P.S.
1982-01-01
Desalination Experimental Facility (DEF) based on multistage flash desalination process has been set up by the Desalination Division of the Bhabha Atomic Research Centre, Bombay. The design parameters of DEF and materials used for various equipment and parts of DEF are mentioned. DEF was operated for 2300 hours in six operational runs. The range of operational parameters maintained during operation and observations on the performance of the materials of construction are given. Detailed comparison has been made for the orocess parameters in DEF and those in a large size plant. (M.G.B.)
Czech Academy of Sciences Publication Activity Database
Papáček, Š.; Čelikovský, Sergej; Rehák, Branislav; Štys, D.
2010-01-01
Roč. 80, č. 6 (2010), s. 1302-1309 ISSN 0378-4754 R&D Projects: GA ČR(CZ) GA102/08/0186 Institutional research plan: CEZ:AV0Z10750506 Keywords : Photosynthetic factory * Experimental design * Parameter estimation * Two-scale modeling Subject RIV: BC - Control Systems Theory Impact factor: 0.812, year: 2010 http://library.utia.cas.cz/separaty/2010/TR/celikovsky-0341543.pdf
Numerical and experimental investigation of geometric parameters in projection welding
DEFF Research Database (Denmark)
Kristensen, Lars; Zhang, Wenqi; Bay, Niels
2000-01-01
parameters by numerical modeling and experimental studies. SORPAS, an FEM program for numerical modeling of resistance welding, is developed as a tool to help in the phase of product design and process optimization in both spot and projection welding. A systematic experimental investigation of projection...... on the numerical and experimental investigations of the geometric parameters in projection welding, guidelines for selection of the geometry and material combinations in product design are proposed. These will be useful and applicable to industry.......Resistance projection welding is widely used for joining of workpieces with almost any geometric combination. This makes standardization of projection welding impossible. In order to facilitate industrial applications of projection welding, systematic investigations are carried out on the geometric...
Bayesian optimal experimental design for the Shock-tube experiment
International Nuclear Information System (INIS)
Terejanu, G; Bryant, C M; Miki, K
2013-01-01
The sequential optimal experimental design formulated as an information-theoretic sensitivity analysis is applied to the ignition delay problem using real experimental. The optimal design is obtained by maximizing the statistical dependence between the model parameters and observables, which is quantified in this study using mutual information. This is naturally posed in the Bayesian framework. The study shows that by monitoring the information gain after each measurement update, one can design a stopping criteria for the experimental process which gives a minimal set of experiments to efficiently learn the Arrhenius parameters.
Optimal Bayesian Experimental Design for Combustion Kinetics
Huan, Xun
2011-01-04
Experimental diagnostics play an essential role in the development and refinement of chemical kinetic models, whether for the combustion of common complex hydrocarbons or of emerging alternative fuels. Questions of experimental design—e.g., which variables or species to interrogate, at what resolution and under what conditions—are extremely important in this context, particularly when experimental resources are limited. This paper attempts to answer such questions in a rigorous and systematic way. We propose a Bayesian framework for optimal experimental design with nonlinear simulation-based models. While the framework is broadly applicable, we use it to infer rate parameters in a combustion system with detailed kinetics. The framework introduces a utility function that reflects the expected information gain from a particular experiment. Straightforward evaluation (and maximization) of this utility function requires Monte Carlo sampling, which is infeasible with computationally intensive models. Instead, we construct a polynomial surrogate for the dependence of experimental observables on model parameters and design conditions, with the help of dimension-adaptive sparse quadrature. Results demonstrate the efficiency and accuracy of the surrogate, as well as the considerable effectiveness of the experimental design framework in choosing informative experimental conditions.
Parameter space of experimental chaotic circuits with high-precision control parameters
Energy Technology Data Exchange (ETDEWEB)
Sousa, Francisco F. G. de; Rubinger, Rero M. [Instituto de Física e Química, Universidade Federal de Itajubá, Itajubá, MG (Brazil); Sartorelli, José C., E-mail: sartorelli@if.usp.br [Universidade de São Paulo, São Paulo, SP (Brazil); Albuquerque, Holokx A. [Departamento de Física, Universidade do Estado de Santa Catarina, Joinville, SC (Brazil); Baptista, Murilo S. [Institute of Complex Systems and Mathematical Biology, SUPA, University of Aberdeen, Aberdeen (United Kingdom)
2016-08-15
We report high-resolution measurements that experimentally confirm a spiral cascade structure and a scaling relationship of shrimps in the Chua's circuit. Circuits constructed using this component allow for a comprehensive characterization of the circuit behaviors through high resolution parameter spaces. To illustrate the power of our technological development for the creation and the study of chaotic circuits, we constructed a Chua circuit and study its high resolution parameter space. The reliability and stability of the designed component allowed us to obtain data for long periods of time (∼21 weeks), a data set from which an accurate estimation of Lyapunov exponents for the circuit characterization was possible. Moreover, this data, rigorously characterized by the Lyapunov exponents, allows us to reassure experimentally that the shrimps, stable islands embedded in a domain of chaos in the parameter spaces, can be observed in the laboratory. Finally, we confirm that their sizes decay exponentially with the period of the attractor, a result expected to be found in maps of the quadratic family.
Optimal Design of Shock Tube Experiments for Parameter Inference
Bisetti, Fabrizio
2014-01-06
We develop a Bayesian framework for the optimal experimental design of the shock tube experiments which are being carried out at the KAUST Clean Combustion Research Center. The unknown parameters are the pre-exponential parameters and the activation energies in the reaction rate expressions. The control parameters are the initial mixture composition and the temperature. The approach is based on first building a polynomial based surrogate model for the observables relevant to the shock tube experiments. Based on these surrogates, a novel MAP based approach is used to estimate the expected information gain in the proposed experiments, and to select the best experimental set-ups yielding the optimal expected information gains. The validity of the approach is tested using synthetic data generated by sampling the PC surrogate. We finally outline a methodology for validation using actual laboratory experiments, and extending experimental design methodology to the cases where the control parameters are noisy.
Khan, M. M. A.; Romoli, L.; Fiaschi, M.; Dini, G.; Sarri, F.
2011-02-01
This paper presents an experimental design approach to process parameter optimization for the laser welding of martensitic AISI 416 and AISI 440FSe stainless steels in a constrained overlap configuration in which outer shell was 0.55 mm thick. To determine the optimal laser-welding parameters, a set of mathematical models were developed relating welding parameters to each of the weld characteristics. These were validated both statistically and experimentally. The quality criteria set for the weld to determine optimal parameters were the minimization of weld width and the maximization of weld penetration depth, resistance length and shearing force. Laser power and welding speed in the range 855-930 W and 4.50-4.65 m/min, respectively, with a fiber diameter of 300 μm were identified as the optimal set of process parameters. However, the laser power and welding speed can be reduced to 800-840 W and increased to 4.75-5.37 m/min, respectively, to obtain stronger and better welds.
An experimental study on effect of process parameters in deep ...
African Journals Online (AJOL)
The effects of various deep drawing process parameters were determined by experimental study with the use of Taguchi fractional factorial design and analysis of variance for AA6111 Aluminum alloy. The optimum process parameters were determined based on their influence on the thickness variation at different regions ...
Optimal Design of Shock Tube Experiments for Parameter Inference
Bisetti, Fabrizio; Knio, Omar
2014-01-01
We develop a Bayesian framework for the optimal experimental design of the shock tube experiments which are being carried out at the KAUST Clean Combustion Research Center. The unknown parameters are the pre-exponential parameters and the activation
Optimal Experimental Design for Large-Scale Bayesian Inverse Problems
Ghattas, Omar
2014-01-06
We develop a Bayesian framework for the optimal experimental design of the shock tube experiments which are being carried out at the KAUST Clean Combustion Research Center. The unknown parameters are the pre-exponential parameters and the activation energies in the reaction rate expressions. The control parameters are the initial mixture composition and the temperature. The approach is based on first building a polynomial based surrogate model for the observables relevant to the shock tube experiments. Based on these surrogates, a novel MAP based approach is used to estimate the expected information gain in the proposed experiments, and to select the best experimental set-ups yielding the optimal expected information gains. The validity of the approach is tested using synthetic data generated by sampling the PC surrogate. We finally outline a methodology for validation using actual laboratory experiments, and extending experimental design methodology to the cases where the control parameters are noisy.
Optimal Experimental Design for Large-Scale Bayesian Inverse Problems
Ghattas, Omar
2014-01-01
We develop a Bayesian framework for the optimal experimental design of the shock tube experiments which are being carried out at the KAUST Clean Combustion Research Center. The unknown parameters are the pre-exponential parameters and the activation
DEFF Research Database (Denmark)
Marcos-Meson, Victor; Pomianowski, Michal Zbigniew; E. Poulsen, Søren
2015-01-01
This paper evaluates the principal design parameters affecting the thermal performance of embedded hydronic Thermally Active Surfaces (TAS), combining the Response Surface Method (RSM) with the Finite Elements Method (FEM). The study ranks the combined effects of the parameters on the heat flux i...
Plasma Arc Cutting Dimensional Accuracy Optimization employing the Parameter Design approach
Kechagias John; Petousis Markos; Vidakis Nectarios; Mastorakis Nikos
2017-01-01
Plasma Arc Cutting (PAC) is a thermal manufacturing process used for metal plates cutting. This work experimentally investigates the influence of process parameters onto the dimensional accuracy performance of the plasma arc cutting process. The cutting parameters studied were cutting speed (mm/min), torch standoff distance (mm), and arc voltage (volts). Linear dimensions of a rectangular workpiece were measured after PAC cutting following the full factorial design experimental approach. For ...
Fractional Factorial Design for Parameter Sweep Experiments Using Nimrod/E
Directory of Open Access Journals (Sweden)
T.C. Peachey
2008-01-01
Full Text Available The techniques of formal experimental design and analysis are powerful tools for scientists and engineers. However, these techniques are currently underused for experiments conducted with computer models. This has motivated the incorporation of experimental design functionality into the Nimrod tool chain. Nimrod has been extensively used for exploration of the response of models to their input parameters; the addition of experimental design tools will combine the efficiency of carefully designed experiments with the power of distributed execution. This paper describes the incorporation of one type of design, the fractional factorial design, and associated analysis tools, into the Nimrod framework. The result provides a convenient environment that automates the design of an experiment, the execution of the jobs on a computational grid and the return of results, and which assists in the interpretation of those results. Several case studies are included which demonstrate various aspects of this approach.
Influence of several experimental parameters on As and Se leaching from coal fly ash samples
International Nuclear Information System (INIS)
Otero-Rey, Jose R.; Mato-Fernandez, Maria J.; Moreda-Pineiro, Jorge; Alonso-Rodriguez, Elia; Muniategui-Lorenzo, Soledad; Lopez-Mahia, Purificacion; Prada-Rodriguez, Dario
2005-01-01
Coal fly ash leaching process for As and Se is studied. Environmental parameters such as pH, temperature, solid-liquid ratio, particle size and leaching time are taken into account in order to simulate As and Se leaching process for disposal coal fly ash. Analysis of reference materials was carried out by using of hydride generation coupled to atomic fluorescence spectrometry. Plackett-Burman experimental design is used to know the significative parameters, and Box-Behnken experimental design is used to refine the results obtained for these significative parameters. pH and temperature shown a hardly influence in leaching process. Furthermore, leaching time was also significative. According our results, it may be assumed that percentage of As and Se leaching in experimental conditions tested is relatively low for acidic fly ashes
Experimental validation of a new heterogeneous mechanical test design
Aquino, J.; Campos, A. Andrade; Souto, N.; Thuillier, S.
2018-05-01
Standard material parameters identification strategies generally use an extensive number of classical tests for collecting the required experimental data. However, a great effort has been made recently by the scientific and industrial communities to support this experimental database on heterogeneous tests. These tests can provide richer information on the material behavior allowing the identification of a more complete set of material parameters. This is a result of the recent development of full-field measurements techniques, like digital image correlation (DIC), that can capture the heterogeneous deformation fields on the specimen surface during the test. Recently, new specimen geometries were designed to enhance the richness of the strain field and capture supplementary strain states. The butterfly specimen is an example of these new geometries, designed through a numerical optimization procedure where an indicator capable of evaluating the heterogeneity and the richness of strain information. However, no experimental validation was yet performed. The aim of this work is to experimentally validate the heterogeneous butterfly mechanical test in the parameter identification framework. For this aim, DIC technique and a Finite Element Model Up-date inverse strategy are used together for the parameter identification of a DC04 steel, as well as the calculation of the indicator. The experimental tests are carried out in a universal testing machine with the ARAMIS measuring system to provide the strain states on the specimen surface. The identification strategy is accomplished with the data obtained from the experimental tests and the results are compared to a reference numerical solution.
Plasma Arc Cutting Dimensional Accuracy Optimization employing the Parameter Design approach
Directory of Open Access Journals (Sweden)
Kechagias John
2017-01-01
Full Text Available Plasma Arc Cutting (PAC is a thermal manufacturing process used for metal plates cutting. This work experimentally investigates the influence of process parameters onto the dimensional accuracy performance of the plasma arc cutting process. The cutting parameters studied were cutting speed (mm/min, torch standoff distance (mm, and arc voltage (volts. Linear dimensions of a rectangular workpiece were measured after PAC cutting following the full factorial design experimental approach. For each one of the three process parameters, three parameter levels were used. Analysis of means (ANOM and analysis of variances (ANOVA were performed in order for the effect of each parameter on the leaner dimensional accuracy to be assessed.
A procedure for multi-objective optimization of tire design parameters
Directory of Open Access Journals (Sweden)
Nikola Korunović
2015-04-01
Full Text Available The identification of optimal tire design parameters for satisfying different requirements, i.e. tire performance characteristics, plays an essential role in tire design. In order to improve tire performance characteristics, formulation and solving of multi-objective optimization problem must be performed. This paper presents a multi-objective optimization procedure for determination of optimal tire design parameters for simultaneous minimization of strain energy density at two distinctive zones inside the tire. It consists of four main stages: pre-analysis, design of experiment, mathematical modeling and multi-objective optimization. Advantage of the proposed procedure is reflected in the fact that multi-objective optimization is based on the Pareto concept, which enables design engineers to obtain a complete set of optimization solutions and choose a suitable tire design. Furthermore, modeling of the relationships between tire design parameters and objective functions based on multiple regression analysis minimizes computational and modeling effort. The adequacy of the proposed tire design multi-objective optimization procedure has been validated by performing experimental trials based on finite element method.
Evaluation of design parameters in soil-structure systems through artificial intelligence
International Nuclear Information System (INIS)
Cremonini, M.G.; Vardanega, C.; Parvis, E.
1989-01-01
This study refers to development of an artificial intelligence tool to evaluate design parameters for a soil-structure system as the foundations of Class 1 buildings of a nuclear power plant (NPP). This is based on an expert analysis of a large amount of information, collected during a comprehensive program of site investigations and laboratory tests and stored on a computer data-bank. The methodology comprises the following steps: organization of the available information on the site characteristics in a data-base; implementation and extensive use of a specific knowledge based expert system (KBES) devoted to both the analysis, interpretation and check of the information in the data-base, and to the evaluation of the design parameters; determination of effective access criteria to the data-base, for purposes of reordering the information and extracting design properties from a large number of experimental data; development of design profiles for both index properties and strength/strain parameters; and final evaluation of the design parameters. Results are obtained in the form of: local and general site stratigraphy; summarized soil index properties, detailing the site setting; static and dynamic stress-strain parameters, G/G max behavior and damping factors; condolidation parameters and OCR ratio; spatial distribution of parameters on site area; identification of specific local conditions; and cross correlation of parameters, thus covering the whole range of design parameters for NPP soil-structure systems
Design parameters and source terms: Volume 1, Design parameters: Revision 0
International Nuclear Information System (INIS)
1987-10-01
The Design Parameters and Source Terms Document was prepared in accordance with DOE request and to provide data for the environmental impact study to be performed in the future for the Deaf Smith County, Texas site for a nuclear waste repository in salt. This document updates a previous unpublished report by Stearns Catalytic Corporation (SCC), entitled ''Design Parameters and Source Terms for a Two-Phase Repository in Salt,'' 1985, to the level of the Site Characterization Plan - Conceptual Design Report. The previous unpublished SCC Study identifies the data needs for the Environmental Assessment effort for seven possible Salt Repository sites
Optimal experimental design with R
Rasch, Dieter; Verdooren, L R; Gebhardt, Albrecht
2011-01-01
Experimental design is often overlooked in the literature of applied and mathematical statistics: statistics is taught and understood as merely a collection of methods for analyzing data. Consequently, experimenters seldom think about optimal design, including prerequisites such as the necessary sample size needed for a precise answer for an experimental question. Providing a concise introduction to experimental design theory, Optimal Experimental Design with R: Introduces the philosophy of experimental design Provides an easy process for constructing experimental designs and calculating necessary sample size using R programs Teaches by example using a custom made R program package: OPDOE Consisting of detailed, data-rich examples, this book introduces experimenters to the philosophy of experimentation, experimental design, and data collection. It gives researchers and statisticians guidance in the construction of optimum experimental designs using R programs, including sample size calculations, hypothesis te...
Influence of experimental parameters on the microencapsulation of a photopolymerizable phase.
Pernot, J M; Brun, H; Pouyet, B; Sergent, M; Phan-Tan-Luu, R
1993-01-01
Conditions of microencapsulation by in situ polycondensation, using melamine-formaldehyde as wall material, are influenced by the chemical nature of the core to encapsulate. In our study concerning the encapsulation of a photopolymerizable phase containing an electrically charged compound, it was necessary to modify the experimental process to obtain capsules of good quality. We used the factorial design method of screening by utilization of an asymmetric matrix, according to the collapsing principle of Addleman. The advantage of this method is that it allows determination of the simultaneous influences of the 11 experimental parameters involved in this preparation. The calculation method can be applied to more than two levels for some of the factors. The continuously varying parameters were altered between two extreme levels, chosen to allow encapsulation. For discontinuous factors, such as the molecular weight of the modifying system or nature of the aminoplast, we used the commercially available compounds, respectively three and four kinds. The results of the obtained capsules were determined by comparing microphotographic pictures. With 16 experiments we found four more factors influencing quality of capsules. We also determined the most favourable levels for the other seven parameters. The results allowed us to find optimal conditions in the experimental field. We obtained capsules of a satisfactory quality for this purpose, using only minimum experimentation.
Experimental kinetic parameters in the thermo-fluid-dynamic modelling of coal combustion
International Nuclear Information System (INIS)
Migliavacca, G.; Perini, M.; Parodi, E.
2001-01-01
The designing and the optimisation of modern and efficient combustion systems are nowadays frequently based on calculation tools for mathematical modelling, which are able to predict the evolution of the process starting from the first principles of physics. Otherwise, in many cases, specific experimental parameters are needed to describe the specific nature of the materials considered in the calculations. It is especially true in the modelling of coal combustion, which is a complex process strongly dependent on the chemical and physical features of the fuel. This paper describes some experimental techniques used to estimate the fundamental kinetic parameters of coal combustion and shows how this data may be introduced in a model calculation to predict the pollutant emissions from a real scale combustion plant [it
Jiang, Chao; Qiao, Mingzhong; Zhu, Peng
2017-12-01
A permanent magnet synchronous motor with radial magnetic circuit and built-in permanent magnet is designed for the electric vehicle. Finite element numerical calculation and experimental measurement are adopted to obtain the direct axis and quadrature axis inductance parameters of the motor which are vital important for the motor control. The calculation method is simple, the measuring principle is clear, the results of numerical calculation and experimental measurement are mutual confirmation. A quick and effective method is provided to obtain the direct axis and quadrature axis inductance parameters of the motor, and then improve the design of motor or adjust the control parameters of the motor controller.
Finite element analysis on badminton racket design parameters
Nasruddin, Fakhrizal Azmy; Syahrom, Ardiyansyah; Abdul Kadir, Mohammed Rafiq; Omar, Abdul Hafidz; Öchsner, Andreas
2016-01-01
This work identifies the characteristics of racket design parameters that influence racket performance. It presents the finite element analysis of several designs of badminton rackets and compares them to experimental results for validation. Designing a racket requires a comprehensive understanding of racket performance characteristics. Essentially, racket performance is related to the sweet spot, which is the spot on the racket head that produces the most power and control when it strikes a shuttlecock. Determining a coefficient of restitution can help to identify the sweet spot on a racket. By analyzing several head shape designs, it becomes apparent that isometric head shape rackets produce better coefficients of restitution compared to oval and round ones. It is recommended that the racket design consist of low string tension, stiffer racket shafts and bigger head size in order to produce higher shuttlecock speed.
A preliminary investigation of the design parameters of an air induction nozzle
Energy Technology Data Exchange (ETDEWEB)
Vashahi, Foad; Ra, Sothea; Lee, Jeekeun [Chonbuk National University, Jeonju (Korea, Republic of); Choi, Yong [National Academy of Agricultural Science, Wanju (Korea, Republic of)
2017-07-15
In the present study, an experimental study on design parameters of an air induction nozzle was performed. These nozzles are capable of producing large size droplets, including microbubbles, which in turn results in high drift reduction. A magnified 2D version of an air induction nozzle was designed and manufactured. The manufactured geometries have the ability to be disassembled easily, thus several geometrical parameters are replaced sequentially. The effects of a venturi throat, air orifices and discharge orifice diameters along with the length of the mixing chamber are analyzed. Analysis of the parameters revealed their strength of prediction on the air liquid ratio and the nozzle performance.
Conceptual design of helium experimental loop
International Nuclear Information System (INIS)
Yu Xingfu; Feng Kaiming
2007-01-01
In a future demonstration fusion power station (DEMO), helium is envisaged as coolant for plasma facing components, such as blanket and dive,or. All these components have a very complex geometry, with many parallel cooling channels, involving a complex helium flow distribution. Test blanket modules (TBM) of this concept will under go various tests in the experimental reactor ITER. For the qualification of TBM, it is indispensable to test mock-ups in a helium loop under realistic pressure and temperature profiles, in order to validate design codes, especially regarding mass flow and heat transition processes in narrow cooling channels. Similar testing must be performed for DEMO blanket, currently under development. A Helium Experimental Loop (HELOOP) is planed to be built for TBM tests. The design parameter of temperature, pressure, flow rate is 550 degree C, 10 MPa, l kg/s respectively. In particular, HELOOP is able to: perform full-scale tests of TBM under realistic conditions; test other components of the He-cooling system in ITER; qualify the purification circuit; obtain information for the design of the ITER cooling system. The main requirements and characteristics of the HELOOP facility and a preliminary conceptual design are described in the paper. (authors)
A critical experimental study of integral physics parameters in simulated LMFBR meltdown cores
International Nuclear Information System (INIS)
Bhattacharyya, S.K.; Wade, D.C.; Bucher, R.G.; Smith, D.M.; McKnight, R.D.; Lesage, L.G.
1978-01-01
Integral physics parameters of several representative, idealized meltdown LMFBR configurations were measured in mockup critical assemblies on the ZPR-9 reactor at Argonne National Laboratory. The experiments were designed to provide data for the validation of analytical methods used in the neutronics part of LMFBR accident analysis. Large core distortions were introduced in these experiments (involving 18.5% core volume) and the reactivity worths of configuration changes were determined. The neutronics parameters measured in the various configurations showed large changes upon core distortion. Both diffusion theory and transport theory methods were shown to mispredict the experimental configuration eigenvalues. In addition, diffusion theory methods were shown to result in a non-conservative misprediction of the experimental configuration change worths. (author)
Reed Johnson, F; Lancsar, Emily; Marshall, Deborah; Kilambi, Vikram; Mühlbacher, Axel; Regier, Dean A; Bresnahan, Brian W; Kanninen, Barbara; Bridges, John F P
2013-01-01
Stated-preference methods are a class of evaluation techniques for studying the preferences of patients and other stakeholders. While these methods span a variety of techniques, conjoint-analysis methods-and particularly discrete-choice experiments (DCEs)-have become the most frequently applied approach in health care in recent years. Experimental design is an important stage in the development of such methods, but establishing a consensus on standards is hampered by lack of understanding of available techniques and software. This report builds on the previous ISPOR Conjoint Analysis Task Force Report: Conjoint Analysis Applications in Health-A Checklist: A Report of the ISPOR Good Research Practices for Conjoint Analysis Task Force. This report aims to assist researchers specifically in evaluating alternative approaches to experimental design, a difficult and important element of successful DCEs. While this report does not endorse any specific approach, it does provide a guide for choosing an approach that is appropriate for a particular study. In particular, it provides an overview of the role of experimental designs for the successful implementation of the DCE approach in health care studies, and it provides researchers with an introduction to constructing experimental designs on the basis of study objectives and the statistical model researchers have selected for the study. The report outlines the theoretical requirements for designs that identify choice-model preference parameters and summarizes and compares a number of available approaches for constructing experimental designs. The task-force leadership group met via bimonthly teleconferences and in person at ISPOR meetings in the United States and Europe. An international group of experimental-design experts was consulted during this process to discuss existing approaches for experimental design and to review the task force's draft reports. In addition, ISPOR members contributed to developing a consensus
A case study on robust optimal experimental design for model calibration of ω-Transaminase
DEFF Research Database (Denmark)
Daele, Timothy, Van; Van Hauwermeiren, Daan; Ringborg, Rolf Hoffmeyer
the experimental space. However, it is expected that more informative experiments can be designed to increase the confidence of the parameter estimates. Therefore, we apply Optimal Experimental Design (OED) to the calibrated model of Shin and Kim (1998). The total number of samples was retained to allow fair......” parameter values are not known before finishing the model calibration. However, it is important that the chosen parameter values are close to the real parameter values, otherwise the OED can possibly yield non-informative experiments. To counter this problem, one can use robust OED. The idea of robust OED......Proper calibration of models describing enzyme kinetics can be quite challenging. This is especially the case for more complex models like transaminase models (Shin and Kim, 1998). The latter fitted model parameters, but the confidence on the parameter estimation was not derived. Hence...
Experimental Engineering: Articulating and Valuing Design Experimentation
DEFF Research Database (Denmark)
Vallgårda, Anna; Grönvall, Erik; Fritsch, Jonas
2017-01-01
In this paper we propose Experimental Engineering as a way to articulate open- ended technological experiments as a legitimate design research practice. Experimental Engineering introduces a move away from an outcome or result driven design process towards an interest in existing technologies and...
Robust Parameter Coordination for Multidisciplinary Design
Institute of Scientific and Technical Information of China (English)
无
2006-01-01
This paper introduced a robust parameter coordination method to analyze parameter uncertainties so as to predict conflicts and coordinate parameters in multidisciplinary design. The proposed method is based on constraints network, which gives a formulated model to analyze the coupling effects between design variables and product specifications. In this model, interval boxes are adopted to describe the uncertainty of design parameters quantitatively to enhance the design robustness. To solve this constraint network model, a general consistent algorithm framework is designed and implemented with interval arithmetic and the genetic algorithm, which can deal with both algebraic and ordinary differential equations. With the help of this method, designers could infer the consistent solution space from the given specifications. A case study involving the design of a bogie dumping system demonstrates the usefulness of this approach.
DEFF Research Database (Denmark)
Van Daele, Timothy; Gernaey, Krist V.; Ringborg, Rolf Hoffmeyer
2017-01-01
The aim of model calibration is to estimate unique parameter values from available experimental data, here applied to a biocatalytic process. The traditional approach of first gathering data followed by performing a model calibration is inefficient, since the information gathered during...... experimentation is not actively used to optimise the experimental design. By applying an iterative robust model-based optimal experimental design, the limited amount of data collected is used to design additional informative experiments. The algorithm is used here to calibrate the initial reaction rate of an ω......-transaminase catalysed reaction in a more accurate way. The parameter confidence region estimated from the Fisher Information Matrix is compared with the likelihood confidence region, which is a more accurate, but also a computationally more expensive method. As a result, an important deviation between both approaches...
Ma, H.; Wang, Q.; Gong, L.; Wang, X.; Yin, W.
2008-01-01
Plackett-Burman design was employed to screen 8 parameters for ethanol production from kitchen garbage by Zymomonas mobilis in simultaneous saccharification and fermentation. The parameters were divided into two parts, four kinds of enzymes and supplementation nutrients. The result indicated that the nutrient inside kitchen garbage could meet the requirement of ethanol production without supplementation, only protease and glucoamylase were needed to accelerate the ethanol production. The opti...
Conceptual design of Fusion Experimental Reactor (FER)
International Nuclear Information System (INIS)
Tone, T.; Fujisawa, N.
1983-01-01
Conceptual design studies of the Fusion Experimental Reactor (FER) have been performed. The FER has an objective of achieving selfignition and demonstrating engineering feasibility as a next generation tokamak to JT-60. Various concepts of the FER have been considered. The reference design is based on a double-null divertor. Optional design studies with some attractive features based on advanced concepts such as pumped limiter and RF current drive have been carried out. Key design parameters are; fusion power of 440 MW, average neutron wall loading of 1MW/m 2 , major radius of 5.5m, plasma minor radius of 1.1m, plasma elongation of 1.5, plasma current of 5.3MA, toroidal beta of 4%, toroidal field on plasma axis of 5.7T and tritium breeding ratio of above unity
Experimental determination of chosen document elements parameters from raster graphics sources
Directory of Open Access Journals (Sweden)
Jiří Rybička
2010-01-01
Full Text Available Visual appearance of documents and their formal quality is considered to be as important as the content quality. Formal and typographical quality of documents can be evaluated by an automated system that processes raster images of documents. A document is described by a formal model that treats a page as an object and also as a set of elements, whereas page elements include text and graphic object. All elements are described by their parameters depending on elements’ type. For future evaluation, mainly text objects are important. This paper describes the experimental determination of chosen document elements parameters from raster images. Techniques for image processing are used, where an image is represented as a matrix of dots and parameter values are extracted. Algorithms for parameter extraction from raster images were designed and were aimed mainly at typographical parameters like indentation, alignment, font size or spacing. Algorithms were tested on a set of 100 images of paragraphs or pages and provide very good results. Extracted parameters can be directly used for typographical quality evaluation.
Bioinspiration: applying mechanical design to experimental biology.
Flammang, Brooke E; Porter, Marianne E
2011-07-01
The production of bioinspired and biomimetic constructs has fostered much collaboration between biologists and engineers, although the extent of biological accuracy employed in the designs produced has not always been a priority. Even the exact definitions of "bioinspired" and "biomimetic" differ among biologists, engineers, and industrial designers, leading to confusion regarding the level of integration and replication of biological principles and physiology. By any name, biologically-inspired mechanical constructs have become an increasingly important research tool in experimental biology, offering the opportunity to focus research by creating model organisms that can be easily manipulated to fill a desired parameter space of structural and functional repertoires. Innovative researchers with both biological and engineering backgrounds have found ways to use bioinspired models to explore the biomechanics of organisms from all kingdoms to answer a variety of different questions. Bringing together these biologists and engineers will hopefully result in an open discourse of techniques and fruitful collaborations for experimental and industrial endeavors.
An Integrated Lumped Parameter-CFD approach for off-design ejector performance evaluation
International Nuclear Information System (INIS)
Besagni, Giorgio; Mereu, Riccardo; Chiesa, Paolo; Inzoli, Fabio
2015-01-01
Highlights: • We validate a CFD approach for a convergent nozzle ejector using global and local measurement. • We evaluate seven RANS turbulence models for convergent nozzle ejector. • We introduce a lumped parameter model for on-design and off-design ejector performance evaluation. • We analyze the relationship between local flow behavior and lumped parameters of the model. • We discuss how to improve predicting capabilities of the model by variable parameters calibrated on CFD simulations. - Abstract: This paper presents an Integrated Lumped Parameter Model-Computational Fluid-Dynamics approach for off-design ejector performance evaluation. The purpose of this approach is to evaluate the entrainment ratio, for a fixed geometry, in both on-design and off-design operating conditions. The proposed model is based on a Lumped Parameter Model (LPM) with variable ejector component efficiencies provided by CFD simulations. The CFD results are used for developing maps for ejector component efficiencies in a broad range of operating conditions. The ejector component efficiency maps couple the CFD and the LPM techniques for building an Integrated LPM-CFD approach. The proposed approach is demonstrated for a convergent nozzle ejector and the paper is structured in four parts. At first, the CFD approach is validated by global and local data and seven Reynolds Averaged Navier Stokes (RANS) turbulence models are compared: the k–ω SST showed good performance and was selected for the rest of the analysis. At second, a Lumped Parameter Model (LPM) for subsonic ejector is developed and the ejector component efficiencies have been defined. At third, the CFD approach is used to investigate the flow field, to analyze its influence on ejector component efficiencies and to propose efficiency correlations and maps linking ejector component efficiencies and local flow quantities. In the last part, the efficiency maps are embedded into the lumped parameter model, thus creating
Fast Bayesian optimal experimental design for seismic source inversion
Long, Quan
2015-07-01
We develop a fast method for optimally designing experiments in the context of statistical seismic source inversion. In particular, we efficiently compute the optimal number and locations of the receivers or seismographs. The seismic source is modeled by a point moment tensor multiplied by a time-dependent function. The parameters include the source location, moment tensor components, and start time and frequency in the time function. The forward problem is modeled by elastodynamic wave equations. We show that the Hessian of the cost functional, which is usually defined as the square of the weighted L2 norm of the difference between the experimental data and the simulated data, is proportional to the measurement time and the number of receivers. Consequently, the posterior distribution of the parameters, in a Bayesian setting, concentrates around the "true" parameters, and we can employ Laplace approximation and speed up the estimation of the expected Kullback-Leibler divergence (expected information gain), the optimality criterion in the experimental design procedure. Since the source parameters span several magnitudes, we use a scaling matrix for efficient control of the condition number of the original Hessian matrix. We use a second-order accurate finite difference method to compute the Hessian matrix and either sparse quadrature or Monte Carlo sampling to carry out numerical integration. We demonstrate the efficiency, accuracy, and applicability of our method on a two-dimensional seismic source inversion problem. © 2015 Elsevier B.V.
Fast Bayesian Optimal Experimental Design for Seismic Source Inversion
Long, Quan
2016-01-06
We develop a fast method for optimally designing experiments [1] in the context of statistical seismic source inversion [2]. In particular, we efficiently compute the optimal number and locations of the receivers or seismographs. The seismic source is modeled by a point moment tensor multiplied by a time-dependent function. The parameters include the source location, moment tensor components, and start time and frequency in the time function. The forward problem is modeled by the elastic wave equations. We show that the Hessian of the cost functional, which is usually defined as the square of the weighted L2 norm of the difference between the experimental data and the simulated data, is proportional to the measurement time and the number of receivers. Consequently, the posterior distribution of the parameters, in a Bayesian setting, concentrates around the true parameters, and we can employ Laplace approximation and speed up the estimation of the expected Kullback-Leibler divergence (expected information gain), the optimality criterion in the experimental design procedure. Since the source parameters span several magnitudes, we use a scaling matrix for efficient control of the condition number of the original Hessian matrix. We use a second-order accurate finite difference method to compute the Hessian matrix and either sparse quadrature or Monte Carlo sampling to carry out numerical integration. We demonstrate the efficiency, accuracy, and applicability of our method on a two-dimensional seismic source inversion problem.
Fast Bayesian Optimal Experimental Design for Seismic Source Inversion
Long, Quan; Motamed, Mohammad; Tempone, Raul
2016-01-01
We develop a fast method for optimally designing experiments [1] in the context of statistical seismic source inversion [2]. In particular, we efficiently compute the optimal number and locations of the receivers or seismographs. The seismic source is modeled by a point moment tensor multiplied by a time-dependent function. The parameters include the source location, moment tensor components, and start time and frequency in the time function. The forward problem is modeled by the elastic wave equations. We show that the Hessian of the cost functional, which is usually defined as the square of the weighted L2 norm of the difference between the experimental data and the simulated data, is proportional to the measurement time and the number of receivers. Consequently, the posterior distribution of the parameters, in a Bayesian setting, concentrates around the true parameters, and we can employ Laplace approximation and speed up the estimation of the expected Kullback-Leibler divergence (expected information gain), the optimality criterion in the experimental design procedure. Since the source parameters span several magnitudes, we use a scaling matrix for efficient control of the condition number of the original Hessian matrix. We use a second-order accurate finite difference method to compute the Hessian matrix and either sparse quadrature or Monte Carlo sampling to carry out numerical integration. We demonstrate the efficiency, accuracy, and applicability of our method on a two-dimensional seismic source inversion problem.
Design parameters of Tokamak-7 system
International Nuclear Information System (INIS)
Ivanov, D.P.; Keilin, V.E.; Klimenko, E.Yu.; Strelkov, V.S.
Superconducting windings for the main magnetic field of Tokamak-7 are discussed. The parameters of this facility are based on the use of commercially available superconducting materials for fields up to 80 kOe. Experimental parameters are described. (U.S.)
DEFF Research Database (Denmark)
This book presents a new, multidisciplinary perspective on and paradigm for integrative experimental design research. It addresses various perspectives on methods, analysis and overall research approach, and how they can be synthesized to advance understanding of design. It explores the foundations...... of experimental approaches and their utility in this domain, and brings together analytical approaches to promote an integrated understanding. The book also investigates where these approaches lead to and how they link design research more fully with other disciplines (e.g. psychology, cognition, sociology......, computer science, management). Above all, the book emphasizes the integrative nature of design research in terms of the methods, theories, and units of study—from the individual to the organizational level. Although this approach offers many advantages, it has inherently led to a situation in current...
Robustness of Adaptive Survey Designs to Inaccuracy of Design Parameters
Directory of Open Access Journals (Sweden)
Burger Joep
2017-09-01
Full Text Available Adaptive survey designs (ASDs optimize design features, given 1 the interactions between the design features and characteristics of sampling units and 2 a set of constraints, such as a budget and a minimum number of respondents. Estimation of the interactions is subject to both random and systematic error. In this article, we propose and evaluate four viewpoints to assess robustness of ASDs to inaccuracy of design parameter estimates: the effect of both imprecision and bias on both ASD structure and ASD performance. We additionally propose three distance measures to compare the structure of ASDs. The methodology is illustrated using a simple simulation study and a more complex but realistic case study on the Dutch Travel Survey. The proposed methodology can be applied to other ASD optimization problems. In our simulation study and case study, the ASD was fairly robust to imprecision, but not to realistic dynamics in the design parameters. To deal with the sensitivity of ASDs to changing design parameters, we recommend to learn and update the design parameters.
Patel, Dipil; Chauhan, Musharraf; Patel, Ravi; Patel, Jayvadan
2012-01-01
The objective of this work was to apply central composite experimental design to investigate main and interaction effect of formulation parameters in optimizing novel fast disintegration tablets formulation using pullulan as diluents. Face centered central composite experimental design was employed to optimize fast disintegration tablet formulation. The variables studied were concentration of diluents (pullulan, X1), superdisintigrant (sodium starch glycolate, X2), and direct compression aid ...
Set membership experimental design for biological systems
Directory of Open Access Journals (Sweden)
Marvel Skylar W
2012-03-01
Full Text Available Abstract Background Experimental design approaches for biological systems are needed to help conserve the limited resources that are allocated for performing experiments. The assumptions used when assigning probability density functions to characterize uncertainty in biological systems are unwarranted when only a small number of measurements can be obtained. In these situations, the uncertainty in biological systems is more appropriately characterized in a bounded-error context. Additionally, effort must be made to improve the connection between modelers and experimentalists by relating design metrics to biologically relevant information. Bounded-error experimental design approaches that can assess the impact of additional measurements on model uncertainty are needed to identify the most appropriate balance between the collection of data and the availability of resources. Results In this work we develop a bounded-error experimental design framework for nonlinear continuous-time systems when few data measurements are available. This approach leverages many of the recent advances in bounded-error parameter and state estimation methods that use interval analysis to generate parameter sets and state bounds consistent with uncertain data measurements. We devise a novel approach using set-based uncertainty propagation to estimate measurement ranges at candidate time points. We then use these estimated measurements at the candidate time points to evaluate which candidate measurements furthest reduce model uncertainty. A method for quickly combining multiple candidate time points is presented and allows for determining the effect of adding multiple measurements. Biologically relevant metrics are developed and used to predict when new data measurements should be acquired, which system components should be measured and how many additional measurements should be obtained. Conclusions The practicability of our approach is illustrated with a case study. This
Achieving optimal SERS through enhanced experimental design.
Fisk, Heidi; Westley, Chloe; Turner, Nicholas J; Goodacre, Royston
2016-01-01
One of the current limitations surrounding surface-enhanced Raman scattering (SERS) is the perceived lack of reproducibility. SERS is indeed challenging, and for analyte detection, it is vital that the analyte interacts with the metal surface. However, as this is analyte dependent, there is not a single set of SERS conditions that are universal. This means that experimental optimisation for optimum SERS response is vital. Most researchers optimise one factor at a time, where a single parameter is altered first before going onto optimise the next. This is a very inefficient way of searching the experimental landscape. In this review, we explore the use of more powerful multivariate approaches to SERS experimental optimisation based on design of experiments and evolutionary computational methods. We particularly focus on colloidal-based SERS rather than thin film preparations as a result of their popularity. © 2015 The Authors. Journal of Raman Spectroscopy published by John Wiley & Sons, Ltd.
Experimental determination of mechanical parameters in sensorless ...
Indian Academy of Sciences (India)
V S S PAVAN KUMAR HARI
pulse width modulation (PWM) selected. The three-phase .... and the simulation and experimental results are presented. ... between 0 and Ts due to the process of PWM. Hence, the .... MATLAB SIMULINK with the machine parameters in.
Surface laser marking optimization using an experimental design approach
Brihmat-Hamadi, F.; Amara, E. H.; Lavisse, L.; Jouvard, J. M.; Cicala, E.; Kellou, H.
2017-04-01
Laser surface marking is performed on a titanium substrate using a pulsed frequency doubled Nd:YAG laser ( λ= 532 nm, τ pulse=5 ns) to process the substrate surface under normal atmospheric conditions. The aim of the work is to investigate, following experimental and statistical approaches, the correlation between the process parameters and the response variables (output), using a Design of Experiment method (DOE): Taguchi methodology and a response surface methodology (RSM). A design is first created using MINTAB program, and then the laser marking process is performed according to the planned design. The response variables; surface roughness and surface reflectance were measured for each sample, and incorporated into the design matrix. The results are then analyzed and the RSM model is developed and verified for predicting the process output for the given set of process parameters values. The analysis shows that the laser beam scanning speed is the most influential operating factor followed by the laser pumping intensity during marking, while the other factors show complex influences on the objective functions.
Quasi-Experimental Designs for Causal Inference
Kim, Yongnam; Steiner, Peter
2016-01-01
When randomized experiments are infeasible, quasi-experimental designs can be exploited to evaluate causal treatment effects. The strongest quasi-experimental designs for causal inference are regression discontinuity designs, instrumental variable designs, matching and propensity score designs, and comparative interrupted time series designs. This…
Design parameters and source terms: Volume 1, Design parameters: Revision 0
International Nuclear Information System (INIS)
1987-09-01
The Design Parameters and Source Terms Document was prepared in accordance with DOE request and to provide data for the environmental impact study to be performed in the future for the Deaf Smith County, Texas site for a nuclear waste repository in salt. This document updates a previous unpublished report to the level of the Site Characterization Plan - Conceptual Design Report, SCP-CDR. The previous unpublished SCC Study identified the data needs for the Environmental Assessment effort for seven possible salt repository sites
Fast Bayesian optimal experimental design and its applications
Long, Quan
2015-01-07
We summarize our Laplace method and multilevel method of accelerating the computation of the expected information gain in a Bayesian Optimal Experimental Design (OED). Laplace method is a widely-used method to approximate an integration in statistics. We analyze this method in the context of optimal Bayesian experimental design and extend this method from the classical scenario, where a single dominant mode of the parameters can be completely-determined by the experiment, to the scenarios where a non-informative parametric manifold exists. We show that by carrying out this approximation the estimation of the expected Kullback-Leibler divergence can be significantly accelerated. While Laplace method requires a concentration of measure, multi-level Monte Carlo method can be used to tackle the problem when there is a lack of measure concentration. We show some initial results on this approach. The developed methodologies have been applied to various sensor deployment problems, e.g., impedance tomography and seismic source inversion.
Bayesian optimal experimental design for priors of compact support
Long, Quan
2016-01-08
In this study, we optimize the experimental setup computationally by optimal experimental design (OED) in a Bayesian framework. We approximate the posterior probability density functions (pdf) using truncated Gaussian distributions in order to account for the bounded domain of the uniform prior pdf of the parameters. The underlying Gaussian distribution is obtained in the spirit of the Laplace method, more precisely, the mode is chosen as the maximum a posteriori (MAP) estimate, and the covariance is chosen as the negative inverse of the Hessian of the misfit function at the MAP estimate. The model related entities are obtained from a polynomial surrogate. The optimality, quantified by the information gain measures, can be estimated efficiently by a rejection sampling algorithm against the underlying Gaussian probability distribution, rather than against the true posterior. This approach offers a significant error reduction when the magnitude of the invariants of the posterior covariance are comparable to the size of the bounded domain of the prior. We demonstrate the accuracy and superior computational efficiency of our method for shock-tube experiments aiming to measure the model parameters of a key reaction which is part of the complex kinetic network describing the hydrocarbon oxidation. In the experiments, the initial temperature and fuel concentration are optimized with respect to the expected information gain in the estimation of the parameters of the target reaction rate. We show that the expected information gain surface can change its shape dramatically according to the level of noise introduced into the synthetic data. The information that can be extracted from the data saturates as a logarithmic function of the number of experiments, and few experiments are needed when they are conducted at the optimal experimental design conditions.
SATELLITE CONSTELLATION DESIGN PARAMETER
Indian Academy of Sciences (India)
First page Back Continue Last page Overview Graphics. SATELLITE CONSTELLATION DESIGN PARAMETER. 1. ORBIT CHARACTERISTICS. ORBITAL HEIGHT >= 20,000 KM. LONGER VISIBILITY; ORBITAL PERIOD. PERTURBATIONS(MINIMUM). SOLAR RADIATION PRESSURE (IMPACTS ECCENTRICITY); LUNI ...
First preliminary design of an experimental fusion reactor
International Nuclear Information System (INIS)
1977-09-01
A preliminary design of a tokamak experimental fusion reactor to be built in the near future is under way. The goals of the reactor are to achieve reactor-level plasma conditions for a sufficiently long operation period and to obtain design, construction and operational experience for the main components of full-scale power reactors. This design covers overall reactor system including plasma characteristics, reactor structure, blanket neutronics, shielding, superconducting magnets, neutral beam injector, electric power supply system, fuel circulating system, reactor cooling system, tritium recovery system and maintenance scheme. The main design parameters are as follows: the reactor fusion power 100 MW, torus radius 6.75 m, plasma radius 1.5 m, first wall radius 1.75 m, toroidal magnet field on axis 6 T, blanket fertile material Li 2 O, coolant He, structural material 316SS and tritium breeding ratio 0.9. (auth.)
Bayesian Optimal Experimental Design Using Multilevel Monte Carlo
Ben Issaid, Chaouki
2015-05-12
Experimental design can be vital when experiments are resource-exhaustive and time-consuming. In this work, we carry out experimental design in the Bayesian framework. To measure the amount of information that can be extracted from the data in an experiment, we use the expected information gain as the utility function, which specifically is the expected logarithmic ratio between the posterior and prior distributions. Optimizing this utility function enables us to design experiments that yield the most informative data about the model parameters. One of the major difficulties in evaluating the expected information gain is that it naturally involves nested integration over a possibly high dimensional domain. We use the Multilevel Monte Carlo (MLMC) method to accelerate the computation of the nested high dimensional integral. The advantages are twofold. First, MLMC can significantly reduce the cost of the nested integral for a given tolerance, by using an optimal sample distribution among different sample averages of the inner integrals. Second, the MLMC method imposes fewer assumptions, such as the asymptotic concentration of posterior measures, required for instance by the Laplace approximation (LA). We test the MLMC method using two numerical examples. The first example is the design of sensor deployment for a Darcy flow problem governed by a one-dimensional Poisson equation. We place the sensors in the locations where the pressure is measured, and we model the conductivity field as a piecewise constant random vector with two parameters. The second one is chemical Enhanced Oil Recovery (EOR) core flooding experiment assuming homogeneous permeability. We measure the cumulative oil recovery, from a horizontal core flooded by water, surfactant and polymer, for different injection rates. The model parameters consist of the endpoint relative permeabilities, the residual saturations and the relative permeability exponents for the three phases: water, oil and
PARAMETER COORDINATION AND ROBUST OPTIMIZATION FOR MULTIDISCIPLINARY DESIGN
Institute of Scientific and Technical Information of China (English)
HU Jie; PENG Yinghong; XIONG Guangleng
2006-01-01
A new parameter coordination and robust optimization approach for multidisciplinary design is presented. Firstly, the constraints network model is established to support engineering change, coordination and optimization. In this model, interval boxes are adopted to describe the uncertainty of design parameters quantitatively to enhance the design robustness. Secondly, the parameter coordination method is presented to solve the constraints network model, monitor the potential conflicts due to engineering changes, and obtain the consistency solution space corresponding to the given product specifications. Finally, the robust parameter optimization model is established, and genetic arithmetic is used to obtain the robust optimization parameter. An example of bogie design is analyzed to show the scheme to be effective.
Analysis of design parameters and flow characteristics of the vortex valve for SIT flow control
International Nuclear Information System (INIS)
Hwang, Young Dong; Chang, Moon Hee; Kim, Seong O.; Kim, Young In.
1997-01-01
This study was performed to provide a technical basis for the development of the vortex valve which will be adopted in Korean Advanced Reactor. The influence of nondimensional and geometrical parameters of the vortex valve were investigated by analyzing the flow field of the vortex chamber, and the performance related parameters were evaluated by utilizing of the published experimental and analytical data. Also the level transients of the stand pipe were investigated by using of the simplified analytical model. In order to obtain the more detailed information on the vortex flow field, three dimensional preliminary analyses for the vortex valve design were conducted by FLUENT code. This study were carried out by using the simplified analytical model of the vortex valve and downstream pipe. However, the detailed analysis on the integrated system of the vortex valve with the as built design data and the required operating conditions should be performed to obtain the more accurate results on the vortex valve behavior. Also the experimental study over a wide range of operating conditions to develop the correlation of the design parameters and the performance verification should be performed for the practical design and engineering applications of the vortex valve. The results of this study can be used as a basic information for the development of the vortex valve design for the SIT of Korean Advanced Reactor. (author). 12 refs., 5 tabs., 33 figs
Quasi experimental designs in pharmacist intervention research.
Krass, Ines
2016-06-01
Background In the field of pharmacist intervention research it is often difficult to conform to the rigorous requirements of the "true experimental" models, especially the requirement of randomization. When randomization is not feasible, a practice based researcher can choose from a range of "quasi-experimental designs" i.e., non-randomised and at time non controlled. Objective The aim of this article was to provide an overview of quasi-experimental designs, discuss their strengths and weaknesses and to investigate their application in pharmacist intervention research over the previous decade. Results In the literature quasi experimental studies may be classified into five broad categories: quasi-experimental design without control groups; quasi-experimental design that use control groups with no pre-test; quasi-experimental design that use control groups and pre-tests; interrupted time series and stepped wedge designs. Quasi-experimental study design has consistently featured in the evolution of pharmacist intervention research. The most commonly applied of all quasi experimental designs in the practice based research literature are the one group pre-post-test design and the non-equivalent control group design i.e., (untreated control group with dependent pre-tests and post-tests) and have been used to test the impact of pharmacist interventions in general medications management as well as in specific disease states. Conclusion Quasi experimental studies have a role to play as proof of concept, in the pilot phases of interventions when testing different intervention components, especially in complex interventions. They serve to develop an understanding of possible intervention effects: while in isolation they yield weak evidence of clinical efficacy, taken collectively, they help build a body of evidence in support of the value of pharmacist interventions across different practice settings and countries. However, when a traditional RCT is not feasible for
Experimental design a chemometric approach
Deming, SN
1987-01-01
Now available in a paperback edition is a book which has been described as ``...an exceptionally lucid, easy-to-read presentation... would be an excellent addition to the collection of every analytical chemist. I recommend it with great enthusiasm.'' (Analytical Chemistry). Unlike most current textbooks, it approaches experimental design from the point of view of the experimenter, rather than that of the statistician. As the reviewer in `Analytical Chemistry' went on to say: ``Deming and Morgan should be given high praise for bringing the principles of experimental design to the level of the p
Simulation-based optimal Bayesian experimental design for nonlinear systems
Huan, Xun
2013-01-01
The optimal selection of experimental conditions is essential to maximizing the value of data for inference and prediction, particularly in situations where experiments are time-consuming and expensive to conduct. We propose a general mathematical framework and an algorithmic approach for optimal experimental design with nonlinear simulation-based models; in particular, we focus on finding sets of experiments that provide the most information about targeted sets of parameters.Our framework employs a Bayesian statistical setting, which provides a foundation for inference from noisy, indirect, and incomplete data, and a natural mechanism for incorporating heterogeneous sources of information. An objective function is constructed from information theoretic measures, reflecting expected information gain from proposed combinations of experiments. Polynomial chaos approximations and a two-stage Monte Carlo sampling method are used to evaluate the expected information gain. Stochastic approximation algorithms are then used to make optimization feasible in computationally intensive and high-dimensional settings. These algorithms are demonstrated on model problems and on nonlinear parameter inference problems arising in detailed combustion kinetics. © 2012 Elsevier Inc.
Selecting Design Parameters for Flying Vehicles
Makeev, V. I.; Strel'nikova, E. A.; Trofimenko, P. E.; Bondar', A. V.
2013-09-01
Studying the influence of a number of design parameters of solid-propellant rockets on the longitudinal and lateral dispersion is an important applied problem. A mathematical model of a rigid body of variable mass moving in a disturbed medium exerting both wave drag and friction is considered. The model makes it possible to determine the coefficients of aerodynamic forces and moments, which affect the motion of vehicles, and to assess the effect of design parameters on their accuracy
ANOVA parameters influence in LCF experimental data and simulation results
Directory of Open Access Journals (Sweden)
Vercelli A.
2010-06-01
Full Text Available The virtual design of components undergoing thermo mechanical fatigue (TMF and plastic strains is usually run in many phases. The numerical finite element method gives a useful instrument which becomes increasingly effective as the geometrical and numerical modelling gets more accurate. The constitutive model definition plays an important role in the effectiveness of the numerical simulation [1, 2] as, for example, shown in Figure 1. In this picture it is shown how a good cyclic plasticity constitutive model can simulate a cyclic load experiment. The component life estimation is the subsequent phase and it needs complex damage and life estimation models [3-5] which take into account of several parameters and phenomena contributing to damage and life duration. The calibration of these constitutive and damage models requires an accurate testing activity. In the present paper the main topic of the research activity is to investigate whether the parameters, which result to be influent in the experimental activity, influence the numerical simulations, thus defining the effectiveness of the models in taking into account of all the phenomena actually influencing the life of the component. To obtain this aim a procedure to tune the parameters needed to estimate the life of mechanical components undergoing TMF and plastic strains is presented for commercial steel. This procedure aims to be easy and to allow calibrating both material constitutive model (for the numerical structural simulation and the damage and life model (for life assessment. The procedure has been applied to specimens. The experimental activity has been developed on three sets of tests run at several temperatures: static tests, high cycle fatigue (HCF tests, low cycle fatigue (LCF tests. The numerical structural FEM simulations have been run on a commercial non linear solver, ABAQUS®6.8. The simulations replied the experimental tests. The stress, strain, thermal results from the thermo
Arpaia, P; Lucariello, G; Spiezia, G
2007-01-01
At European Centre of Nuclear Research (CERN), within the new Large Hadron Collider (LHC) project, measurements of magnetic flux with uncertainty of 10 ppm at a few of decades of Hz for several minutes are required. With this aim, a new Fast Digital Integrator (FDI) has been developed in cooperation with University of Sannio, Italy [1]. This paper deals with the final design tuning for achieving target uncertainty by means of experimental statistical parameter design.
Chemical-Based Formulation Design: Virtual Experimentation
DEFF Research Database (Denmark)
Conte, Elisa; Gani, Rafiqul
This paper presents a software, the virtual Product-Process Design laboratory (virtual PPD-lab) and the virtual experimental scenarios for design/verification of consumer oriented liquid formulated products where the software can be used. For example, the software can be employed for the design......, the additives and/or their mixtures (formulations). Therefore, the experimental resources can focus on a few candidate product formulations to find the best product. The virtual PPD-lab allows various options for experimentations related to design and/or verification of the product. For example, the selection...... design, model adaptation). All of the above helps to perform virtual experiments by blending chemicals together and observing their predicted behaviour. The paper will highlight the application of the virtual PPD-lab in the design and/or verification of different consumer products (paint formulation...
HAMMLAB 1999 experimental control room: design - design rationale - experiences
International Nuclear Information System (INIS)
Foerdestroemmen, N. T.; Meyer, B. D.; Saarni, R.
1999-01-01
A presentation of HAMMLAB 1999 experimental control room, and the accumulated experiences gathered in the areas of design and design rationale as well as user experiences. It is concluded that HAMMLAB 1999 experimental control room is a realistic, compact and efficient control room well suited as an Advanced NPP Control Room (ml)
Experimental verification of different parameters influencing the fatigue S/N-curve
International Nuclear Information System (INIS)
Roos, E.; Maile, K.; Herter, K.-H.; Schuler, X.
2005-01-01
For the construction, design and operation of nuclear components the appropriate technical codes and standards provide detailed stress analysis procedures, material data and a design philosophy which guarantees a reliable behavior throughout the specified lifetime. Especially for cyclic stress evaluation the different codes and standards provide different fatigue analyses procedures to be performed considering the various (specified or measured) loading histories which are of mechanical and/or thermal origin and the geometric complexities of the components. In order to fully understand the background of the fatigue analysis included in the codes and standards as well as of the fatigue design curves used as a limiting criteria (to determine the fatigue life usage factor), it is important to understand the history, background as well as the methodologies which are important for the design engineers to get reliable results. The design rules according to the technical codes and standards provide for explicit consideration of cyclic operation, using design fatigue curves of allowable alternating loads (allowable stress or strain amplitudes) vs. number of loading cycles (S/N-curves), specific rules for assessing the cumulative fatigue damage (cumulative fatigue life usage factor) caused by different specified or monitored load cycles. The influence of different factors like welds, environment, surface finish, temperature, mean stress and size must be taken into consideration. In the paper parameters influencing the S/N-curves used within a fatigue analysis, like different type of material, the surface finish, the temperature, the difference between unwelded and welded areas, the strain rate as well as the influences of notches are verified on the basis of experimental results obtained by specimens testing in the LCF regime for high strain amplitudes. Thus safety margins relevant for the assessment of fatigue life depending on the different influencing parameters are
Shen, Jiajian; Tryggestad, Erik; Younkin, James E; Keole, Sameer R; Furutani, Keith M; Kang, Yixiu; Herman, Michael G; Bues, Martin
2017-10-01
To accurately model the beam delivery time (BDT) for a synchrotron-based proton spot scanning system using experimentally determined beam parameters. A model to simulate the proton spot delivery sequences was constructed, and BDT was calculated by summing times for layer switch, spot switch, and spot delivery. Test plans were designed to isolate and quantify the relevant beam parameters in the operation cycle of the proton beam therapy delivery system. These parameters included the layer switch time, magnet preparation and verification time, average beam scanning speeds in x- and y-directions, proton spill rate, and maximum charge and maximum extraction time for each spill. The experimentally determined parameters, as well as the nominal values initially provided by the vendor, served as inputs to the model to predict BDTs for 602 clinical proton beam deliveries. The calculated BDTs (T BDT ) were compared with the BDTs recorded in the treatment delivery log files (T Log ): ∆t = T Log -T BDT . The experimentally determined average layer switch time for all 97 energies was 1.91 s (ranging from 1.9 to 2.0 s for beam energies from 71.3 to 228.8 MeV), average magnet preparation and verification time was 1.93 ms, the average scanning speeds were 5.9 m/s in x-direction and 19.3 m/s in y-direction, the proton spill rate was 8.7 MU/s, and the maximum proton charge available for one acceleration is 2.0 ± 0.4 nC. Some of the measured parameters differed from the nominal values provided by the vendor. The calculated BDTs using experimentally determined parameters matched the recorded BDTs of 602 beam deliveries (∆t = -0.49 ± 1.44 s), which were significantly more accurate than BDTs calculated using nominal timing parameters (∆t = -7.48 ± 6.97 s). An accurate model for BDT prediction was achieved by using the experimentally determined proton beam therapy delivery parameters, which may be useful in modeling the interplay effect and patient throughput. The model may
Yousefieh, M.; Shamanian, M.; Saatchi, A.
2012-09-01
Taguchi design method with L9 orthogonal array was implemented to optimize the pulsed current gas tungsten arc welding parameters for the hardness and the toughness of super duplex stainless steel (SDSS, UNS S32760) welds. In this regard, the hardness and the toughness were considered as performance characteristics. Pulse current, background current, % on time, and pulse frequency were chosen as main parameters. Each parameter was varied at three different levels. As a result of pooled analysis of variance, the pulse current is found to be the most significant factor for both the hardness and the toughness of SDSS welds by percentage contribution of 71.81 for hardness and 78.18 for toughness. The % on time (21.99%) and the background current (17.81%) had also the next most significant effect on the hardness and the toughness, respectively. The optimum conditions within the selected parameter values for hardness were found as the first level of pulse current (100 A), third level of background current (70 A), first level of % on time (40%), and first level of pulse frequency (1 Hz), while they were found as the second level of pulse current (120 A), second level of background current (60 A), second level of % on time (60%), and third level of pulse frequency (5 Hz) for toughness. The Taguchi method was found to be a promising tool to obtain the optimum conditions for such studies. Finally, in order to verify experimental results, confirmation tests were carried out at optimum working conditions. Under these conditions, there were good agreements between the predicted and the experimental results for the both hardness and toughness.
International Nuclear Information System (INIS)
Reid, R.L.; Galambos, J.D.; Peng, Y.K.M.
1988-09-01
Energy confinement scaling is a major concern in the design of the International Thermonuclear Experimental Reactor (ITER). The existing database for tokamaks can be fitted with a number of different confinement scaling expressions that have similar degrees of approximation. These scaling laws predict confinement times for ITER that vary by over an order of magnitude. The uncertainties in the form and magnitude of these scaling laws must be substantially reduced before the plasma performance of ITER can be predicted with adequate reliability. The TETRA systems code is used to calculate the dependence of major ITER parameters on the scaling laws currently in use. Design constraints of interest in the present phase of ITER consideration are used, and the minimum-cost devices arising from these constraints are reviewed. 9 refs., 13 figs., 4 tabs
International Nuclear Information System (INIS)
Sahin, Bayram; Demir, Alparslan
2008-01-01
This paper reports the heat transfer enhancement and corresponding pressure drop over a flat surface equipped with circular cross section perforated pin fins in a rectangular channel. The channel had a cross section area of 100-250 mm 2 . The experiments covered the following ranges: Reynolds number 13500-42,000, clearance ratio (C/H) 0, 0.33 and 1 and interfin spacing ratio (S y /D) 1.208, 1.524, 1.944 and 3.417. Correlation equations were developed for the heat transfer, friction factor and enhancement efficiency. The experimental results showed that the use of circular cross section pin fins may lead to heat transfer enhancement. Enhancement efficiencies varied between 1.4 and 2.6 depending on clearance ratio and interfin spacing ratio. Using a Taguchi experimental design method, optimum design parameters and their levels were investigated. Nusselt number and friction factor were considered as performance parameters. An L 9 (3 3 ) orthogonal array was selected as an experimental plan. First of all, each goal was optimized separately. Then, all the goals were optimized together, considering the priority of the goals, and the optimum results were found to be Reynolds number of 42,000, fin height of 50 mm and streamwise distance between fins of 51 mm
Coal Recycling from Tailings using Flotation with 2-Level Experimental Design Techniques
Directory of Open Access Journals (Sweden)
Sajjad Jannesar Malakooti
2012-12-01
Full Text Available In this study, the possibility of producing coal with less than 11% ash from tailings of flotation process was investigated. The effect of six flotation parameters: collector type, collector consumption, frother type, frother consumption, pulp density and mixing rate were studied on a sample from a tailing dam. A software based experimental design approach (DX7 was applied to determine and model effective parameters as well as flotation optimization through fractional factorial. It was shown that collector type and flotation machine mixing rate were the most effective parameters on ash content of concentrate. The results indicated that the production of a desired ash content concentrate, i.e.
Directory of Open Access Journals (Sweden)
Sangyeong Jeong
2017-10-01
Full Text Available This paper proposes an experimental optimization method for a wireless power transfer (WPT system. The power transfer characteristics of a WPT system with arbitrary loads and various types of coupling and compensation networks can be extracted by frequency domain measurements. The various performance parameters of the WPT system, such as input real/imaginary/apparent power, power factor, efficiency, output power and voltage gain, can be accurately extracted in a frequency domain by a single passive measurement. Subsequently, the design parameters can be efficiently tuned by separating the overall design steps into two parts. The extracted performance parameters of the WPT system were validated with time-domain experiments.
DEFF Research Database (Denmark)
Nguyen, Thong Tien
2011-01-01
Experimental designs are required in widely used techniques in marketing research, especially for preference-based conjoint analysis and discrete-choice studies. Ideally, marketing researchers prefer orthogonal designs because this technique could give uncorrelated parameter estimates. However, o...... for implementing designs that is efficient enough to estimate model with N brands, each brand have K attributes, and brand attribute has specific levels. The paper also illustrates an example in food consumption study.......Experimental designs are required in widely used techniques in marketing research, especially for preference-based conjoint analysis and discrete-choice studies. Ideally, marketing researchers prefer orthogonal designs because this technique could give uncorrelated parameter estimates. However......, orthogonal design is not available for every situation. Instead, efficient design based on computerized design algorithm is always available. This paper presents the method of efficient design for estimating brand models having attribute and availability cross effects. The paper gives a framework...
Modal Parameter Identification of New Design of Vertical Axis Wind Turbine
DEFF Research Database (Denmark)
Chougule, Prasad; Nielsen, Søren R.K.
2013-01-01
Vertical axis wind turbines have lower power efficiency than the horizontal axis wind turbines. However vertical axis wind turbines are proven to be economical and noise free on smaller scale. A new design of three bladed vertical axis wind turbine by using two airfoils in construction of each...... blade has been proposed to improve power efficiency. The purpose of two airfoils in blade design of vertical axis wind turbine is to create high lift which in turns gives higher power output. In such case the structural parameter identification is important to understand the system behavior due to its...... first kind of design before experimental analysis. Therefore a study is carried out to determine the natural frequency to avoid unstable state of the system due to rotational frequency of rotor. The present paper outlines a conceptual design of vertical axis wind turbine and a modal analysis by using...
The role of experimental typography in designing logotypes
Pogačnik, Tadeja
2014-01-01
Designing logotypes is an important part of graphic design. Great logotypes are designed using custom made typefaces. Therefore, it is very important, especially for the typographic designer, to have practical experience and be up to date with all trends in the field of experimental typefaces design, also called experimental typography. In my thesis statement, I carefully examined the problems of experimental typography - which allows more creative and free typography designing for different ...
Conceptual design study of fusion experimental reactor (FY86 FER)
International Nuclear Information System (INIS)
Saito, Ryusei; Kashihara, Shin-ichiro; Itoh, Shin-ichi
1987-08-01
This report describes the results of conceptual design study on plant systems for the Fusion Experimental Reactor (FY86 FER). Design studies for FER plant systems have been continued from FY85, especially for design modifications made in accordance with revisions of plasma scaling parameters and system improvements. This report describes 1) system construction, 2) site and reactor building plan, 3) repaire and maintenance system, 4) tritium circulation system, 5) heating, ventilation and air conditioning system, 6) tritium clean-up system, 7) cooling and baking system, 8) waste treatment and storage system, 9) control system, 10) electric power system, 11) site factory plan, all of which are a part of FY86 design work. The plant systems described in this report generally have been based on the FY86 FER (ACS Reactor) which is an one of the six candidates for FER. (author)
Experimental design in chemistry: A tutorial.
Leardi, Riccardo
2009-10-12
In this tutorial the main concepts and applications of experimental design in chemistry will be explained. Unfortunately, nowadays experimental design is not as known and applied as it should be, and many papers can be found in which the "optimization" of a procedure is performed one variable at a time. Goal of this paper is to show the real advantages in terms of reduced experimental effort and of increased quality of information that can be obtained if this approach is followed. To do that, three real examples will be shown. Rather than on the mathematical aspects, this paper will focus on the mental attitude required by experimental design. The readers being interested to deepen their knowledge of the mathematical and algorithmical part can find very good books and tutorials in the references [G.E.P. Box, W.G. Hunter, J.S. Hunter, Statistics for Experimenters: An Introduction to Design, Data Analysis, and Model Building, John Wiley & Sons, New York, 1978; R. Brereton, Chemometrics: Data Analysis for the Laboratory and Chemical Plant, John Wiley & Sons, New York, 1978; R. Carlson, J.E. Carlson, Design and Optimization in Organic Synthesis: Second Revised and Enlarged Edition, in: Data Handling in Science and Technology, vol. 24, Elsevier, Amsterdam, 2005; J.A. Cornell, Experiments with Mixtures: Designs, Models and the Analysis of Mixture Data, in: Series in Probability and Statistics, John Wiley & Sons, New York, 1991; R.E. Bruns, I.S. Scarminio, B. de Barros Neto, Statistical Design-Chemometrics, in: Data Handling in Science and Technology, vol. 25, Elsevier, Amsterdam, 2006; D.C. Montgomery, Design and Analysis of Experiments, 7th edition, John Wiley & Sons, Inc., 2009; T. Lundstedt, E. Seifert, L. Abramo, B. Thelin, A. Nyström, J. Pettersen, R. Bergman, Chemolab 42 (1998) 3; Y. Vander Heyden, LC-GC Europe 19 (9) (2006) 469].
Experimental design of a waste glass study
International Nuclear Information System (INIS)
Piepel, G.F.; Redgate, P.E.; Hrma, P.
1995-04-01
A Composition Variation Study (CVS) is being performed to support a future high-level waste glass plant at Hanford. A total of 147 glasses, covering a broad region of compositions melting at approximately 1150 degrees C, were tested in five statistically designed experimental phases. This paper focuses on the goals, strategies, and techniques used in designing the five phases. The overall strategy was to investigate glass compositions on the boundary and interior of an experimental region defined by single- component, multiple-component, and property constraints. Statistical optimal experimental design techniques were used to cover various subregions of the experimental region in each phase. Empirical mixture models for glass properties (as functions of glass composition) from previous phases wee used in designing subsequent CVS phases
Norinder, U; Högberg, T
1992-04-01
The advantageous approach of using an experimentally designed training set as the basis for establishing a quantitative structure-activity relationship with good predictive capability is described. The training set was selected from a fractional factorial design scheme based on a principal component description of physico-chemical parameters of aromatic substituents. The derived model successfully predicts the activities of additional substituted benzamides of 6-methoxy-N-(4-piperidyl)salicylamide type. The major influence on activity of the 3-substituent is demonstrated.
Optimizing experimental parameters for the projection requirement in HAADF-STEM tomography
International Nuclear Information System (INIS)
Aveyard, R.; Zhong, Z.; Batenburg, K.J.; Rieger, B.
2017-01-01
Highlights: • The extent to which HAADF-STEM meets the projection requirement has been studied. • Multislice simulations used to model beam propagation and study signal linearity. • Propagation in crystalline and amorphous materials considered. • Optimal experimental set-up for the projection requirement is discussed. - Abstract: Tomographic reconstruction algorithms offer a means by which a tilt-series of transmission images can be combined to yield a three dimensional model of the specimen. Conventional reconstruction algorithms assume that the measured signal is a linear projection of some property, typically the density, of the material. Here we report the use of multislice simulations to investigate the extent to which this assumption is met in HAADF-STEM imaging. The use of simulations allows for a systematic survey of a range of materials and microscope parameters to inform optimal experimental design. Using this approach it is demonstrated that the imaging of amorphous materials is in good agreement with the projection assumption in most cases. Images of crystalline specimens taken along zone-axes are found to be poorly suited for conventional linear reconstruction algorithms due to channelling effects which produce enhanced intensities compared with off-axis images, and poor compliance with the projection requirement. Off-axis images are found to be suitable for reconstruction, though they do not strictly meet the linearity requirement in most cases. It is demonstrated that microscope parameters can be selected to yield improved compliance with the projection requirement.
Optimizing experimental parameters for the projection requirement in HAADF-STEM tomography
Energy Technology Data Exchange (ETDEWEB)
Aveyard, R., E-mail: r.a.aveyard@tudelft.nl [Department of Imaging Physics, Delft University of Technology, 2628CJ Delft (Netherlands); Zhong, Z.; Batenburg, K.J. [Centrum Wiskunde and Informatica, Science Park 123, NL-1098 XG Amsterdam (Netherlands); Rieger, B., E-mail: b.rieger@tudelft.nl [Department of Imaging Physics, Delft University of Technology, 2628CJ Delft (Netherlands)
2017-06-15
Highlights: • The extent to which HAADF-STEM meets the projection requirement has been studied. • Multislice simulations used to model beam propagation and study signal linearity. • Propagation in crystalline and amorphous materials considered. • Optimal experimental set-up for the projection requirement is discussed. - Abstract: Tomographic reconstruction algorithms offer a means by which a tilt-series of transmission images can be combined to yield a three dimensional model of the specimen. Conventional reconstruction algorithms assume that the measured signal is a linear projection of some property, typically the density, of the material. Here we report the use of multislice simulations to investigate the extent to which this assumption is met in HAADF-STEM imaging. The use of simulations allows for a systematic survey of a range of materials and microscope parameters to inform optimal experimental design. Using this approach it is demonstrated that the imaging of amorphous materials is in good agreement with the projection assumption in most cases. Images of crystalline specimens taken along zone-axes are found to be poorly suited for conventional linear reconstruction algorithms due to channelling effects which produce enhanced intensities compared with off-axis images, and poor compliance with the projection requirement. Off-axis images are found to be suitable for reconstruction, though they do not strictly meet the linearity requirement in most cases. It is demonstrated that microscope parameters can be selected to yield improved compliance with the projection requirement.
Energy Technology Data Exchange (ETDEWEB)
Man, Jun [Zhejiang Provincial Key Laboratory of Agricultural Resources and Environment, Institute of Soil and Water Resources and Environmental Science, College of Environmental and Resource Sciences, Zhejiang University, Hangzhou China; Zhang, Jiangjiang [Zhejiang Provincial Key Laboratory of Agricultural Resources and Environment, Institute of Soil and Water Resources and Environmental Science, College of Environmental and Resource Sciences, Zhejiang University, Hangzhou China; Li, Weixuan [Pacific Northwest National Laboratory, Richland Washington USA; Zeng, Lingzao [Zhejiang Provincial Key Laboratory of Agricultural Resources and Environment, Institute of Soil and Water Resources and Environmental Science, College of Environmental and Resource Sciences, Zhejiang University, Hangzhou China; Wu, Laosheng [Department of Environmental Sciences, University of California, Riverside California USA
2016-10-01
The ensemble Kalman filter (EnKF) has been widely used in parameter estimation for hydrological models. The focus of most previous studies was to develop more efficient analysis (estimation) algorithms. On the other hand, it is intuitively understandable that a well-designed sampling (data-collection) strategy should provide more informative measurements and subsequently improve the parameter estimation. In this work, a Sequential Ensemble-based Optimal Design (SEOD) method, coupled with EnKF, information theory and sequential optimal design, is proposed to improve the performance of parameter estimation. Based on the first-order and second-order statistics, different information metrics including the Shannon entropy difference (SD), degrees of freedom for signal (DFS) and relative entropy (RE) are used to design the optimal sampling strategy, respectively. The effectiveness of the proposed method is illustrated by synthetic one-dimensional and two-dimensional unsaturated flow case studies. It is shown that the designed sampling strategies can provide more accurate parameter estimation and state prediction compared with conventional sampling strategies. Optimal sampling designs based on various information metrics perform similarly in our cases. The effect of ensemble size on the optimal design is also investigated. Overall, larger ensemble size improves the parameter estimation and convergence of optimal sampling strategy. Although the proposed method is applied to unsaturated flow problems in this study, it can be equally applied in any other hydrological problems.
GA BASED GLOBAL OPTIMAL DESIGN PARAMETERS FOR ...
African Journals Online (AJOL)
Journal of Modeling, Design and Management of Engineering Systems ... DESIGN PARAMETERS FOR CONSECUTIVE REACTIONS IN SERIALLY CONNECTED ... for the process equipments such as chemical reactors used in industries.
Chemicals-Based Formulation Design: Virtual Experimentations
DEFF Research Database (Denmark)
Conte, Elisa; Gani, Rafiqul
2011-01-01
This paper presents a systematic procedure for virtual experimentations related to the design of liquid formulated products. All the experiments that need to be performed when designing a liquid formulated product (lotion), such as ingredients selection and testing, solubility tests, property mea...... on the design of an insect repellent lotion will show that the software is an essential instrument in decision making, and that it reduces time and resources since experimental efforts can be focused on one or few product alternatives....
Optimal design criteria - prediction vs. parameter estimation
Waldl, Helmut
2014-05-01
G-optimality is a popular design criterion for optimal prediction, it tries to minimize the kriging variance over the whole design region. A G-optimal design minimizes the maximum variance of all predicted values. If we use kriging methods for prediction it is self-evident to use the kriging variance as a measure of uncertainty for the estimates. Though the computation of the kriging variance and even more the computation of the empirical kriging variance is computationally very costly and finding the maximum kriging variance in high-dimensional regions can be time demanding such that we cannot really find the G-optimal design with nowadays available computer equipment in practice. We cannot always avoid this problem by using space-filling designs because small designs that minimize the empirical kriging variance are often non-space-filling. D-optimality is the design criterion related to parameter estimation. A D-optimal design maximizes the determinant of the information matrix of the estimates. D-optimality in terms of trend parameter estimation and D-optimality in terms of covariance parameter estimation yield basically different designs. The Pareto frontier of these two competing determinant criteria corresponds with designs that perform well under both criteria. Under certain conditions searching the G-optimal design on the above Pareto frontier yields almost as good results as searching the G-optimal design in the whole design region. In doing so the maximum of the empirical kriging variance has to be computed only a few times though. The method is demonstrated by means of a computer simulation experiment based on data provided by the Belgian institute Management Unit of the North Sea Mathematical Models (MUMM) that describe the evolution of inorganic and organic carbon and nutrients, phytoplankton, bacteria and zooplankton in the Southern Bight of the North Sea.
Design parameters to control synthetic gene expression in Escherichia coli.
Directory of Open Access Journals (Sweden)
Mark Welch
Full Text Available BACKGROUND: Production of proteins as therapeutic agents, research reagents and molecular tools frequently depends on expression in heterologous hosts. Synthetic genes are increasingly used for protein production because sequence information is easier to obtain than the corresponding physical DNA. Protein-coding sequences are commonly re-designed to enhance expression, but there are no experimentally supported design principles. PRINCIPAL FINDINGS: To identify sequence features that affect protein expression we synthesized and expressed in E. coli two sets of 40 genes encoding two commercially valuable proteins, a DNA polymerase and a single chain antibody. Genes differing only in synonymous codon usage expressed protein at levels ranging from undetectable to 30% of cellular protein. Using partial least squares regression we tested the correlation of protein production levels with parameters that have been reported to affect expression. We found that the amount of protein produced in E. coli was strongly dependent on the codons used to encode a subset of amino acids. Favorable codons were predominantly those read by tRNAs that are most highly charged during amino acid starvation, not codons that are most abundant in highly expressed E. coli proteins. Finally we confirmed the validity of our models by designing, synthesizing and testing new genes using codon biases predicted to perform well. CONCLUSION: The systematic analysis of gene design parameters shown in this study has allowed us to identify codon usage within a gene as a critical determinant of achievable protein expression levels in E. coli. We propose a biochemical basis for this, as well as design algorithms to ensure high protein production from synthetic genes. Replication of this methodology should allow similar design algorithms to be empirically derived for any expression system.
Considering RNAi experimental design in parasitic helminths.
Dalzell, Johnathan J; Warnock, Neil D; McVeigh, Paul; Marks, Nikki J; Mousley, Angela; Atkinson, Louise; Maule, Aaron G
2012-04-01
Almost a decade has passed since the first report of RNA interference (RNAi) in a parasitic helminth. Whilst much progress has been made with RNAi informing gene function studies in disparate nematode and flatworm parasites, substantial and seemingly prohibitive difficulties have been encountered in some species, hindering progress. An appraisal of current practices, trends and ideals of RNAi experimental design in parasitic helminths is both timely and necessary for a number of reasons: firstly, the increasing availability of parasitic helminth genome/transcriptome resources means there is a growing need for gene function tools such as RNAi; secondly, fundamental differences and unique challenges exist for parasite species which do not apply to model organisms; thirdly, the inherent variation in experimental design, and reported difficulties with reproducibility undermine confidence. Ideally, RNAi studies of gene function should adopt standardised experimental design to aid reproducibility, interpretation and comparative analyses. Although the huge variations in parasite biology and experimental endpoints make RNAi experimental design standardization difficult or impractical, we must strive to validate RNAi experimentation in helminth parasites. To aid this process we identify multiple approaches to RNAi experimental validation and highlight those which we deem to be critical for gene function studies in helminth parasites.
Directory of Open Access Journals (Sweden)
Khaled MAMMAR
2013-11-01
Full Text Available In this paper, a new approach based on Experimental of design methodology (DoE is used to estimate the optimal of unknown model parameters proton exchange membrane fuel cell (PEMFC. This proposed approach combines the central composite face-centered (CCF and numerical PEMFC electrochemical. Simulation results obtained using electrochemical model help to predict the cell voltage in terms of inlet partial pressures of hydrogen and oxygen, stack temperature, and operating current. The value of the previous model and (CCF design methodology is used for parametric analysis of electrochemical model. Thus it is possible to evaluate the relative importance of each parameter to the simulation accuracy. However this methodology is able to define the exact values of the parameters from the manufacture data. It was tested for the BCS 500-W stack PEM Generator, a stack rated at 500 W, manufactured by American Company BCS Technologies FC.
Energy Technology Data Exchange (ETDEWEB)
Beltran, R. G.; Talero, A.
2004-07-01
This article describes the experimental setup used to obtain design parameters for a wind driven refrigeration equipment. The system compressor is directly coupled to the wind mill and will provide refrigeration to a community located in La Guajira in northern Colombia. The testing on the experimental installation assessed the refrigeration capacity that could be provided by an open type commercial compressor coupled to the wind mill axis. Power and torque requirements have been evaluated for different wind mill rotational speeds. An assessment of the local conditions relating to wind speed, frequency and preferred direction for the installation site has been made based on measurements by the Meteorological National Institute and independent data from other sources. (Author)
International Nuclear Information System (INIS)
Anith Khairunnisa Ghazali; Mohd Sabri Minhat
2015-01-01
Reactor TRIGA PUSPATI (RTP) undergoes safe operation for more than 30 years and the only research reactor in Malaysia. The main safety feature of Instrumentation and Control (I and C) system design is such that any failure in the electronic, or its associated components, does not lead to an uncontrolled rate of reactivity. There are no best models for RTP simulation was designed for study and research. Therefore, the comparison for I&C parameters are very essential, to design the best RTP model using MATLAB/ Simulink as close as the RTP. The simulation of TRIGA reactor type already develop using desktop reactor simulator such as Personal Computer Transient Analyzer (PCTRAN). The experimental data from RTP and simulation of PCTRAN shows some similarities and differences due to certain limitation. Currently, the structured RTP simulation was designed using MATLAB and Simulink tool that consist of ideal fission chamber, controller, control rod position, height to worth and RTP model. The study on this paper focus on comparison between real data from RTP and simulation result from PCTRAN on I&C parameters such as water level, fuel temperature, bulk temperature, power rated and rod position. The error analysis due to some similarities and differences of I&C parameters shall be obtained and analysed. The result will be used as reference for proposed new structured of RTP model. (author)
Design considerations for ITER [International Thermonuclear Experimental Reactor] magnet systems
International Nuclear Information System (INIS)
Henning, C.D.; Miller, J.R.
1988-01-01
The International Thermonuclear Experimental Reactor (ITER) is now completing a definition phase as a beginning of a three-year design effort. Preliminary parameters for the superconducting magnet system have been established to guide further and more detailed design work. Radiation tolerance of the superconductors and insulators has been of prime importance, since it sets requirements for the neutron-shield dimension and sensitively influences reactor size. The major levels of mechanical stress in the structure appear in the cases of the inboard legs of the toroidal-field (TF) coils. The cases of the poloidal-field (PF) coils must be made thin or segmented to minimize eddy current heating during inductive plasma operation. As a result, the winding packs of both the TF and PF coils includes significant fractions of steel. The TF winding pack provides support against in-plane separating loads but offers little support against out-of-plane loads, unless shear-bonding of the conductors can be maintained. The removal of heat due to nuclear and ac loads has not been a fundamental limit to design, but certainly has non-negligible economic consequences. We present here preliminary ITER magnetic systems design parameters taken from trade studies, designs, and analyses performed by the Home Teams of the four ITER participants, by the ITER Magnet Design Unit in Garching, and by other participants at workshops organized by the Magnet Design Unit. The work presented here reflects the efforts of many, but the responsibility for the opinions expressed is the authors'. 4 refs., 3 figs., 4 tabs
Online optimal experimental re-design in robotic parallel fed-batch cultivation facilities.
Cruz Bournazou, M N; Barz, T; Nickel, D B; Lopez Cárdenas, D C; Glauche, F; Knepper, A; Neubauer, P
2017-03-01
We present an integrated framework for the online optimal experimental re-design applied to parallel nonlinear dynamic processes that aims to precisely estimate the parameter set of macro kinetic growth models with minimal experimental effort. This provides a systematic solution for rapid validation of a specific model to new strains, mutants, or products. In biosciences, this is especially important as model identification is a long and laborious process which is continuing to limit the use of mathematical modeling in this field. The strength of this approach is demonstrated by fitting a macro-kinetic differential equation model for Escherichia coli fed-batch processes after 6 h of cultivation. The system includes two fully-automated liquid handling robots; one containing eight mini-bioreactors and another used for automated at-line analyses, which allows for the immediate use of the available data in the modeling environment. As a result, the experiment can be continually re-designed while the cultivations are running using the information generated by periodical parameter estimations. The advantages of an online re-computation of the optimal experiment are proven by a 50-fold lower average coefficient of variation on the parameter estimates compared to the sequential method (4.83% instead of 235.86%). The success obtained in such a complex system is a further step towards a more efficient computer aided bioprocess development. Biotechnol. Bioeng. 2017;114: 610-619. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.
Multi-objective optimization design and experimental investigation of centrifugal fan performance
Zhang, Lei; Wang, Songling; Hu, Chenxing; Zhang, Qian
2013-11-01
Current studies of fan performance optimization mainly focus on two aspects: one is to improve the blade profile, and another is only to consider the influence of single impeller structural parameter on fan performance. However, there are few studies on the comprehensive effect of the key parameters such as blade number, exit stagger angle of blade and the impeller outlet width on the fan performance. The G4-73 backward centrifugal fan widely used in power plants is selected as the research object. Based on orthogonal design and BP neural network, a model for predicting the centrifugal fan performance parameters is established, and the maximum relative errors of the total pressure and efficiency are 0.974% and 0.333%, respectively. Multi-objective optimization of total pressure and efficiency of the fan is conducted with genetic algorithm, and the optimum combination of impeller structural parameters is proposed. The optimized parameters of blade number, exit stagger angle of blade and the impeller outlet width are seperately 14, 43.9°, and 21 cm. The experiments on centrifugal fan performance and noise are conducted before and after the installation of the new impeller. The experimental results show that with the new impeller, the total pressure of fan increases significantly in total range of the flow rate, and the fan efficiency is improved when the relative flow is above 75%, also the high efficiency area is broadened. Additionally, in 65% -100% relative flow, the fan noise is reduced. Under the design operating condition, total pressure and efficiency of the fan are improved by 6.91% and 0.5%, respectively. This research sheds light on the considering of comprehensive effect of impeller structrual parameters on fan performance, and a new impeller can be designed to satisfy the engineering demand such as energy-saving, noise reduction or solving air pressure insufficiency for power plants.
Characterization of an erbium doped fiber amplifier starting from its experimental parameters
International Nuclear Information System (INIS)
Bello J, M.; Kuzin, E.A.; Ibarra E, B.; Tellez G, R.
2007-01-01
In this paper we describe a method to characterize the gain of an erbium-doped fiber amplifier (EDFA) through the numerical simulation of the signal beam along the amplifier. The simulation is based on a model constituted by the propagation and rate equations for an erbium-doped fiber. The manipulation of these equations allows us to regroup the parameters present in an EDFA, which we have named the A, B, C, D parameters, and they can be obtained experimentally from an erbium-doped fiber. Experimental results show that the measurement of these parameters allow us to estimate with very good correspondence the amplifier gain. (Author)
Experimental Design: Review and Comment.
1984-02-01
creativity. Innovative modifications and extensions of classical experimental designs were developed and many useful articles were published in a short...Pjrazolone Industrielle ," Bulletin de la Soci~t6 Chimique de France, 11-12, 1171-1174. LI, K. C. (1983), "Minimaxity for Randomized Designs: Some
An Experimental Study of the Local Parameters of a Damaged Cantilever
DEFF Research Database (Denmark)
Rytter, A.; Brincker, Rune; Kirkegaard, Poul Henning
of results from experimental tests with six hollow section steel cantilevers containing a fatigue crack introduced from a narrow laser cut slot. The modal parameters have been identified for different size and location of a crack. The modal parameters have been estimated by mean of frequency domain and time...
An Experimental Study of the Modal Parameters of a Damaged Cantilever
DEFF Research Database (Denmark)
Rytter, A.; Brincker, Rune; Kirkegaard, Poul Henning
of results from experimental tests with six hollow section steel cantilevers containing a fatigue crack introduced from a narrow laser cut slot. The modal parameters have been identified for different size and location of a crack. The modal parameters have been estimated by mean of frequency domain and time...
International Nuclear Information System (INIS)
Arai, Taketoshi; Sato, Sadao; Tani, Yutaro
1977-12-01
Design principles and criteria of fuels and graphites have been studied to determine the main design parameters of a reference core MARK-III of the Experimental Multi-purpose Very High Temperature Reactor. The present status of research and development for HTGR fuels and graphites is reviewed from a standpoint of their integrity and safety aspects, and is compared to the specific design requirements for the VHTR fuels and graphites. Consequently, reasonable materials specifications, safety criteria and design analysis methods are presented for coated fuel particle, fuel compact, graphite sleeve, core support graphite and neutron absorber material. These design principles and criteria will be refined by further experimental investigations. (auth.)
Flow cytometry: design, development and experimental validation
International Nuclear Information System (INIS)
Seigneur, Alain
1987-01-01
The flow cytometry techniques allow the analysis and sorting of living biologic cells at rates above five to ten thousand events per second. After a short review, we present in this report the design and development of a 'high-tech' apparatus intended for research laboratories and the experimental results. The first part deals with the physical principles allowing morphologic and functional analysis of cells or cellular components. The measured parameters are as follows: electrical resistance pulse sizing, light scattering and fluorescence. Hydrodynamic centering is used, and in the same way, the division of a water-stream into droplets leading to electrostatic sorting of particles. The second part deals with the apparatus designed by the 'Commissariat a l'Energie Atomique' (C.E.A.) and industrialised by 'ODAM' (ATC 3000). The last part of this thesis work is the performance evaluations of this cyto-meter. The difference between the two size measurement methods are analyzed: electrical resistance pulse sizing versus small-angle light scattering. By an original optics design, high sensitivity has been reached in the fluorescence measurement: the equivalent noise corresponds to six hundred fluorescein isothiocyanate (FITC) molecules. The sorting performances have also been analyzed and the cell viability proven. (author) [fr
International Nuclear Information System (INIS)
Dos-Santos, N.
2013-01-01
The work performed during this thesis focused on uncertainty propagation (nuclear data, technological uncertainties, calculation biases,...) on integral parameters, and the development of a novel approach enabling to reduce this uncertainty a priori directly from the design phase of a new experimental program. This approach is based on a multi-parameter multi-criteria extension of representativeness and transposition theories. The first part of this PhD work covers an optimization study of sensitivity and uncertainty calculation schemes to different modeling scales (cell, assembly and whole core) for LWRs and FBRs. A degraded scheme, based on standard and generalized perturbation theories, has been validated for the calculation of uncertainty propagation to various integral quantities of interest. It demonstrated the good a posteriori representativeness of the EPICURE experiment for the validation of mixed UOX-MOX loadings, as the importance of some nuclear data in the power tilt phenomenon in large LWR cores. The second part of this work was devoted to methods and tools development for the optimized design of experimental programs in ZPRs. Those methods are based on multi-parameters representativeness using simultaneously various quantities of interest. Finally, an original study has been conducted on the rigorous estimation of correlations between experimental programs in the transposition process. The coupling of experimental correlations and multi-parametric representativeness approach enables to efficiently design new programs, able to answer additional qualification requirements on calculation tools. (author) [fr
Facility for Advanced Accelerator Experimental Tests at SLAC (FACET) Conceptual Design Report
Energy Technology Data Exchange (ETDEWEB)
Amann, J.; Bane, K.; /SLAC
2009-10-30
This Conceptual Design Report (CDR) describes the design of FACET. It will be updated to stay current with the developing design of the facility. This CDR begins as the baseline conceptual design and will evolve into an 'as-built' manual for the completed facility. The Executive Summary, Chapter 1, gives an introduction to the FACET project and describes the salient features of its design. Chapter 2 gives an overview of FACET. It describes the general parameters of the machine and the basic approaches to implementation. The FACET project does not include the implementation of specific scientific experiments either for plasma wake-field acceleration for other applications. Nonetheless, enough work has been done to define potential experiments to assure that the facility can meet the requirements of the experimental community. Chapter 3, Scientific Case, describes the planned plasma wakefield and other experiments. Chapter 4, Technical Description of FACET, describes the parameters and design of all technical systems of FACET. FACET uses the first two thirds of the existing SLAC linac to accelerate the beam to about 20GeV, and compress it with the aid of two chicanes, located in Sector 10 and Sector 20. The Sector 20 area will include a focusing system, the generic experimental area and the beam dump. Chapter 5, Management of Scientific Program, describes the management of the scientific program at FACET. Chapter 6, Environment, Safety and Health and Quality Assurance, describes the existing programs at SLAC and their application to the FACET project. It includes a preliminary analysis of safety hazards and the planned mitigation. Chapter 7, Work Breakdown Structure, describes the structure used for developing the cost estimates, which will also be used to manage the project. The chapter defines the scope of work of each element down to level 3.
Facility for Advanced Accelerator Experimental Tests at SLAC (FACET) Conceptual Design Report
International Nuclear Information System (INIS)
Amann, J.; Bane, K.
2009-01-01
This Conceptual Design Report (CDR) describes the design of FACET. It will be updated to stay current with the developing design of the facility. This CDR begins as the baseline conceptual design and will evolve into an 'as-built' manual for the completed facility. The Executive Summary, Chapter 1, gives an introduction to the FACET project and describes the salient features of its design. Chapter 2 gives an overview of FACET. It describes the general parameters of the machine and the basic approaches to implementation. The FACET project does not include the implementation of specific scientific experiments either for plasma wake-field acceleration for other applications. Nonetheless, enough work has been done to define potential experiments to assure that the facility can meet the requirements of the experimental community. Chapter 3, Scientific Case, describes the planned plasma wakefield and other experiments. Chapter 4, Technical Description of FACET, describes the parameters and design of all technical systems of FACET. FACET uses the first two thirds of the existing SLAC linac to accelerate the beam to about 20GeV, and compress it with the aid of two chicanes, located in Sector 10 and Sector 20. The Sector 20 area will include a focusing system, the generic experimental area and the beam dump. Chapter 5, Management of Scientific Program, describes the management of the scientific program at FACET. Chapter 6, Environment, Safety and Health and Quality Assurance, describes the existing programs at SLAC and their application to the FACET project. It includes a preliminary analysis of safety hazards and the planned mitigation. Chapter 7, Work Breakdown Structure, describes the structure used for developing the cost estimates, which will also be used to manage the project. The chapter defines the scope of work of each element down to level 3.
International Nuclear Information System (INIS)
Wang, Guodong; He, Zhen; Xue, Li; Cui, Qingan; Lv, Shanshan; Zhou, Panpan
2017-01-01
Factors which significantly affect product reliability are of great interest to reliability practitioners. This paper proposes a bootstrap-based methodology for identifying significant factors when both location and scale parameters of the smallest extreme value distribution vary over experimental factors. An industrial thermostat experiment is presented, analyzed, and discussed as an illustrative example. The analysis results show that 1) the misspecification of a constant scale parameter may lead to misidentify spurious effects; 2) the important factors identified by different bootstrap methods (i.e., percentile bootstrapping, bias-corrected percentile bootstrapping, and bias-corrected and accelerated percentile bootstrapping) are different; 3) the number of factors affecting 10th percentile lifetime significantly is less than the number of important factors identified at 63.21th percentile. - Highlights: • Product reliability is improved by design of experiments under both scale and location parameters of smallest extreme value distribution vary with experimental factors. • A bootstrap-based methodology is proposed to identify important factors which affect 100pth lifetime percentile significantly. • Bootstrapping confidence intervals associating experimental factors are obtained by using three bootstrap methods (i.e., percentile bootstrapping, bias-corrected percentile bootstrapping, and bias-corrected and accelerated percentile bootstrapping). • The important factors identified by different bootstrap methods are different. • The number of factors affecting 10th percentile significantly is less than the number of important factors identified at 63.21th percentile.
Pant, Apourv; Rai, J P N
2018-04-15
Two phase bioreactor was constructed, designed and developed to evaluate the chlorpyrifos remediation. Six biotic and abiotic factors (substrate-loading rate, slurry phase pH, slurry phase dissolved oxygen (DO), soil water ratio, temperature and soil micro flora load) were evaluated by design of experimental (DOE) methodology employing Taguchi's orthogonal array (OA). The selected six factors were considered at two levels L-8 array (2^7, 15 experiments) in the experimental design. The optimum operating conditions obtained from the methodology showed enhanced chlorpyrifos degradation from 283.86µg/g to 955.364µg/g by overall 70.34% of enhancement. In the present study, with the help of few well defined experimental parameters a mathematical model was constructed to understand the complex bioremediation process and optimize the approximate parameters upto great accuracy. Copyright © 2017 Elsevier Inc. All rights reserved.
Directory of Open Access Journals (Sweden)
Muhammad Aslam
2015-07-01
Full Text Available In the present study, MODFLOW-MT3D groundwater model was employed to perform numerical experimentation to develop design and operational parameters for SW (Skimming Wells based on hydrogeology and groundwater salinity conditions of Chaj Doab, Punjab, Pakistan. Numerical experimentation resulted in: (i a 1-strainer SW with discharge of 14 l/s (litres per second and penetration of 30% resulted in more saltwater upconing at 8 hours/day well operation compared to that occurred at 4 hours/day operation; (ii a 1-strainer well with penetration of 30% and operation of 8 hours/day caused higher saltwater upconing at 14 l/s discharge compared to that at 9 l/s discharge; (iii a 4-strainer well with penetration of 30% and operation of 8 hours/day also caused more saltwater upconing at 14 l/s well discharge compared to that at 9 l/s discharge. Similar trend was found for a 8- strainer well; and (iv 1- or 4- or 8-strainer well with 30-60% penetration, 9-14 l/s discharge and 4-8 hours/day operation could provide pumped groundwater of salinity less than 1000 ppm. Considering hydro-chemical performance and costs of wells, a 4-strainer well with 30% penetration, 9- 14 l/s discharge and 4-8 hours/day operation is recommended to skim groundwater of salinity less than 1000 ppm in Chaj Doab of Punjab, Pakistan
Toward efficient computation of the expected relative entropy for nonlinear experimental design
International Nuclear Information System (INIS)
Coles, Darrell; Prange, Michael
2012-01-01
The expected relative entropy between prior and posterior model-parameter distributions is a Bayesian objective function in experimental design theory that quantifies the expected gain in information of an experiment relative to a previous state of knowledge. The expected relative entropy is a preferred measure of experimental quality because it can handle nonlinear data-model relationships, an important fact due to the ubiquity of nonlinearity in science and engineering and its effects on post-inversion parameter uncertainty. This objective function does not necessarily yield experiments that mediate well-determined systems, but, being a Bayesian quality measure, it rigorously accounts for prior information which constrains model parameters that may be only weakly constrained by the optimized dataset. Historically, use of the expected relative entropy has been limited by the computing and storage requirements associated with high-dimensional numerical integration. Herein, a bifocal algorithm is developed that makes these computations more efficient. The algorithm is demonstrated on a medium-sized problem of sampling relaxation phenomena and on a large problem of source–receiver selection for a 2D vertical seismic profile. The method is memory intensive but workarounds are discussed. (paper)
Beck, Joakim
2018-02-19
In calculating expected information gain in optimal Bayesian experimental design, the computation of the inner loop in the classical double-loop Monte Carlo requires a large number of samples and suffers from underflow if the number of samples is small. These drawbacks can be avoided by using an importance sampling approach. We present a computationally efficient method for optimal Bayesian experimental design that introduces importance sampling based on the Laplace method to the inner loop. We derive the optimal values for the method parameters in which the average computational cost is minimized for a specified error tolerance. We use three numerical examples to demonstrate the computational efficiency of our method compared with the classical double-loop Monte Carlo, and a single-loop Monte Carlo method that uses the Laplace approximation of the return value of the inner loop. The first demonstration example is a scalar problem that is linear in the uncertain parameter. The second example is a nonlinear scalar problem. The third example deals with the optimal sensor placement for an electrical impedance tomography experiment to recover the fiber orientation in laminate composites.
Beck, Joakim; Dia, Ben Mansour; Espath, Luis F. R.; Long, Quan; Tempone, Raúl
2018-06-01
In calculating expected information gain in optimal Bayesian experimental design, the computation of the inner loop in the classical double-loop Monte Carlo requires a large number of samples and suffers from underflow if the number of samples is small. These drawbacks can be avoided by using an importance sampling approach. We present a computationally efficient method for optimal Bayesian experimental design that introduces importance sampling based on the Laplace method to the inner loop. We derive the optimal values for the method parameters in which the average computational cost is minimized according to the desired error tolerance. We use three numerical examples to demonstrate the computational efficiency of our method compared with the classical double-loop Monte Carlo, and a more recent single-loop Monte Carlo method that uses the Laplace method as an approximation of the return value of the inner loop. The first example is a scalar problem that is linear in the uncertain parameter. The second example is a nonlinear scalar problem. The third example deals with the optimal sensor placement for an electrical impedance tomography experiment to recover the fiber orientation in laminate composites.
Multi-objective experimental design for (13)C-based metabolic flux analysis.
Bouvin, Jeroen; Cajot, Simon; D'Huys, Pieter-Jan; Ampofo-Asiama, Jerry; Anné, Jozef; Van Impe, Jan; Geeraerd, Annemie; Bernaerts, Kristel
2015-10-01
(13)C-based metabolic flux analysis is an excellent technique to resolve fluxes in the central carbon metabolism but costs can be significant when using specialized tracers. This work presents a framework for cost-effective design of (13)C-tracer experiments, illustrated on two different networks. Linear and non-linear optimal input mixtures are computed for networks for Streptomyces lividans and a carcinoma cell line. If only glucose tracers are considered as labeled substrate for a carcinoma cell line or S. lividans, the best parameter estimation accuracy is obtained by mixtures containing high amounts of 1,2-(13)C2 glucose combined with uniformly labeled glucose. Experimental designs are evaluated based on a linear (D-criterion) and non-linear approach (S-criterion). Both approaches generate almost the same input mixture, however, the linear approach is favored due to its low computational effort. The high amount of 1,2-(13)C2 glucose in the optimal designs coincides with a high experimental cost, which is further enhanced when labeling is introduced in glutamine and aspartate tracers. Multi-objective optimization gives the possibility to assess experimental quality and cost at the same time and can reveal excellent compromise experiments. For example, the combination of 100% 1,2-(13)C2 glucose with 100% position one labeled glutamine and the combination of 100% 1,2-(13)C2 glucose with 100% uniformly labeled glutamine perform equally well for the carcinoma cell line, but the first mixture offers a decrease in cost of $ 120 per ml-scale cell culture experiment. We demonstrated the validity of a multi-objective linear approach to perform optimal experimental designs for the non-linear problem of (13)C-metabolic flux analysis. Tools and a workflow are provided to perform multi-objective design. The effortless calculation of the D-criterion can be exploited to perform high-throughput screening of possible (13)C-tracers, while the illustrated benefit of multi
Suhaily, M.; Che Hassan, C. H.; Jaharah, A. G.; Afifah, M. A.; Nor Khairusshima, M. K.
2018-01-01
In this research study, it presents a comprehensive mathematical model for correlating the influences of drilling parameters on the delamination factor during the drilling of woven kenaf fiber reinforced epoxy composite laminates using the Box Behnken experimental design. The purpose of this study is to investigate the influence of drilling parameters such as cutting speed, feed rate and drill sizes on the delamination produced when drilling woven kenaf reinforced epoxy composite using the non-coated HSS drill bits. The damage generated on the woven kenaf reinforced epoxy composite laminates were observed both at the entrance and exit surface during the drilling operation. The experiments were conducted according to the Box Behnken experimental designs.
The Translation between Functional Requirements and Design Parameters for Robust Design
DEFF Research Database (Denmark)
Göhler, Simon Moritz; Husung, Stephan; Howard, Thomas J.
2016-01-01
The specification of and justification for design parameter (DP) tolerances are primarily based on the acceptable variation of the functions’ performance and the functions’ sensitivity to the design parameters. However, why certain tolerances are needed is often not transparent, especially...... computer aided functional tolerancing. Non-optimal tolerances yield potentials for cost improvements in manufacturing and more consistency of the functional performance of the product. In this contribution a framework is proposed to overcome the observed problems and increase the clarity, transparency...... and traceability of tolerances by analyzing the translation between the DPs and their influence on the final function....
Directory of Open Access Journals (Sweden)
Walid Nabgan
2016-08-01
Full Text Available Full factorial experimental design with 32 runs was used to investigate the significant and interaction variable of the reaction parameters on phenol steam reforming toward hydrogen production. Effects of selected factors on the phenol conversion (Y1 and hydrogen yield (Y2 were evaluated. These factors were as follows: (A temperature (500 and 800 °C; (B feed flow rate (0.16–0.46 mL/min; (C catalyst weight (0.1–0.3 g; (D Ni-Co ratio (0–1; and (E phenol concentration in the feed (2–10 wt %. Ni and Co over ZrO2 support for catalytic performance of phenol steam reforming (SRP was prepared by the impregnation method. The result indicated that all the main independent variables had significant influence on the dependent variable of Y1 and Y2 with a range of 2.7%–96.8% and 21.4%–72.4%, respectively. Additionally, some interaction variables like AE, BE, CE, and DE have also influenced the Y1 and Y2 responses. This design showed that the best initial conditions that produced maximum Y1 and Y2 responses were at 800 °C, 0.16 mL/min feed flow rate, 0.3 g of catalyst, 0 ratio of Ni-Co (Co/ZrO2, and 10 wt % of phenol in the feed, where the phenol conversion was predicted to be 94.98% and the hydrogen yield was predicted to be 67.4%. Within the limits the variables were examined, a regression model which well-fitted the experimental data was proposed. The regression model were reduced to simplify and to get the significant regression coefficient with p-value less than 0.05.
Tuning Parameters in Heuristics by Using Design of Experiments Methods
Arin, Arif; Rabadi, Ghaith; Unal, Resit
2010-01-01
With the growing complexity of today's large scale problems, it has become more difficult to find optimal solutions by using exact mathematical methods. The need to find near-optimal solutions in an acceptable time frame requires heuristic approaches. In many cases, however, most heuristics have several parameters that need to be "tuned" before they can reach good results. The problem then turns into "finding best parameter setting" for the heuristics to solve the problems efficiently and timely. One-Factor-At-a-Time (OFAT) approach for parameter tuning neglects the interactions between parameters. Design of Experiments (DOE) tools can be instead employed to tune the parameters more effectively. In this paper, we seek the best parameter setting for a Genetic Algorithm (GA) to solve the single machine total weighted tardiness problem in which n jobs must be scheduled on a single machine without preemption, and the objective is to minimize the total weighted tardiness. Benchmark instances for the problem are available in the literature. To fine tune the GA parameters in the most efficient way, we compare multiple DOE models including 2-level (2k ) full factorial design, orthogonal array design, central composite design, D-optimal design and signal-to-noise (SIN) ratios. In each DOE method, a mathematical model is created using regression analysis, and solved to obtain the best parameter setting. After verification runs using the tuned parameter setting, the preliminary results for optimal solutions of multiple instances were found efficiently.
Sequential experimental design based generalised ANOVA
Energy Technology Data Exchange (ETDEWEB)
Chakraborty, Souvik, E-mail: csouvik41@gmail.com; Chowdhury, Rajib, E-mail: rajibfce@iitr.ac.in
2016-07-15
Over the last decade, surrogate modelling technique has gained wide popularity in the field of uncertainty quantification, optimization, model exploration and sensitivity analysis. This approach relies on experimental design to generate training points and regression/interpolation for generating the surrogate. In this work, it is argued that conventional experimental design may render a surrogate model inefficient. In order to address this issue, this paper presents a novel distribution adaptive sequential experimental design (DA-SED). The proposed DA-SED has been coupled with a variant of generalised analysis of variance (G-ANOVA), developed by representing the component function using the generalised polynomial chaos expansion. Moreover, generalised analytical expressions for calculating the first two statistical moments of the response, which are utilized in predicting the probability of failure, have also been developed. The proposed approach has been utilized in predicting probability of failure of three structural mechanics problems. It is observed that the proposed approach yields accurate and computationally efficient estimate of the failure probability.
Methodology to estimate parameters of an excitation system based on experimental conditions
Energy Technology Data Exchange (ETDEWEB)
Saavedra-Montes, A.J. [Carrera 80 No 65-223, Bloque M8 oficina 113, Escuela de Mecatronica, Universidad Nacional de Colombia, Medellin (Colombia); Calle 13 No 100-00, Escuela de Ingenieria Electrica y Electronica, Universidad del Valle, Cali, Valle (Colombia); Ramirez-Scarpetta, J.M. [Calle 13 No 100-00, Escuela de Ingenieria Electrica y Electronica, Universidad del Valle, Cali, Valle (Colombia); Malik, O.P. [2500 University Drive N.W., Electrical and Computer Engineering Department, University of Calgary, Calgary, Alberta (Canada)
2011-01-15
A methodology to estimate the parameters of a potential-source controlled rectifier excitation system model is presented in this paper. The proposed parameter estimation methodology is based on the characteristics of the excitation system. A comparison of two pseudo random binary signals, two sampling periods for each one, and three estimation algorithms is also presented. Simulation results from an excitation control system model and experimental results from an excitation system of a power laboratory setup are obtained. To apply the proposed methodology, the excitation system parameters are identified at two different levels of the generator saturation curve. The results show that it is possible to estimate the parameters of the standard model of an excitation system, recording two signals and the system operating in closed loop with the generator. The normalized sum of squared error obtained with experimental data is below 10%, and with simulation data is below 5%. (author)
Radiometric parameters in freshwater samples of Centro Experimental Aramar (CTMSP/Brazil)
Energy Technology Data Exchange (ETDEWEB)
Moraes, Marco Antonio P.V. [Laboratorio Radioecologico (LARE), Ipero, SP (Brazil). Dept. de Seguranca Nuclear; Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)
2011-07-01
Experimental results are described obtained with gamma spectrometry, alpha and beta gross counts, liquid scintillation and fluorometry techniques for the measurement of background radiation in surface water samples, collected in Centro Experimental Aramar and surroundings, from 1988 to 2009. The estimated average background radiation concentrations in water samples in this region are low, related to the low level detection limits of the techniques, and indicates good water quality parameters, and low interference in the environment in Centro Experimental Aramar and region. (author)
Optimization of Loudspeaker Part Design Parameters by Air Viscosity Damping Effect
Yue Hu; Xilu Zhao; Takao Yamaguchi; Manabu Sasajima; Yoshio Koike; Akira Hara
2016-01-01
This study optimized the design parameters of a cone loudspeaker as an example of high flexibility of the product design. We developed an acoustic analysis software program that considers the impact of damping caused by air viscosity. In sound reproduction, it is difficult to optimize each parameter of the loudspeaker design. To overcome the limitation of the design problem in practice, this study presents an acoustic analysis algorithm to optimize the design parameters of the loudspeaker. Th...
Nilsson, Ingemar; Polla, Magnus O
2012-10-01
Drug design is a multi-parameter task present in the analysis of experimental data for synthesized compounds and in the prediction of new compounds with desired properties. This article describes the implementation of a binned scoring and composite ranking scheme for 11 experimental parameters that were identified as key drivers in the MC4R project. The composite ranking scheme was implemented in an AstraZeneca tool for analysis of project data, thereby providing an immediate re-ranking as new experimental data was added. The automated ranking also highlighted compounds overlooked by the project team. The successful implementation of a composite ranking on experimental data led to the development of an equivalent virtual score, which was based on Free-Wilson models of the parameters from the experimental ranking. The individual Free-Wilson models showed good to high predictive power with a correlation coefficient between 0.45 and 0.97 based on the external test set. The virtual ranking adds value to the selection of compounds for synthesis but error propagation must be controlled. The experimental ranking approach adds significant value, is parameter independent and can be tuned and applied to any drug discovery project.
Using factorial experimental design to evaluate the separation of plastics by froth flotation.
Salerno, Davide; Jordão, Helga; La Marca, Floriana; Carvalho, M Teresa
2018-03-01
This paper proposes the use of factorial experimental design as a standard experimental method in the application of froth flotation to plastic separation instead of the commonly used OVAT method (manipulation of one variable at a time). Furthermore, as is common practice in minerals flotation, the parameters of the kinetic model were used as process responses rather than the recovery of plastics in the separation products. To explain and illustrate the proposed methodology, a set of 32 experimental tests was performed using mixtures of two polymers with approximately the same density, PVC and PS (with mineral charges), with particle size ranging from 2 to 4 mm. The manipulated variables were frother concentration, air flow rate and pH. A three-level full factorial design was conducted. The models establishing the relationships between the manipulated variables and their interactions with the responses (first order kinetic model parameters) were built. The Corrected Akaike Information Criterion was used to select the best fit model and an analysis of variance (ANOVA) was conducted to identify the statistically significant terms of the model. It was shown that froth flotation can be used to efficiently separate PVC from PS with mineral charges by reducing the floatability of PVC, which largely depends on the action of pH. Within the tested interval, this is the factor that most affects the flotation rate constants. The results obtained show that the pure error may be of the same magnitude as the sum of squares of the errors, suggesting that there is significant variability within the same experimental conditions. Thus, special care is needed when evaluating and generalizing the process. Copyright © 2017 Elsevier Ltd. All rights reserved.
Performance of a solar chimney by varying design parameters
CSIR Research Space (South Africa)
Kumirai, T
2015-08-01
Full Text Available the design of solar chimneys to ensure optimal performance. The purpose of this chapter is to discuss the performance of an example solar chimney by varying the design parameters and examining their effects on the interior ventilation performance... chimney by varying design parameters Tichaona Kumirai, Researcher, Built Environment CSIR Jan-Hendrik Grobler, DPSS CSIR Dr D.C.U. Conradie, Senior researcher, Built Environment CSIR 1 Introduction Trombe walls and solar chimneys are not widely...
DESIGN PARAMETERS OF CENTRIFUGAL COMPRESSOR INDUCER
Directory of Open Access Journals (Sweden)
Saim KOÇAK
1998-03-01
Full Text Available Design characteristics of centrifugal compressor impellers working with compressible fluids are analyzed, and the design parameters of inducer are defined. The effects of incidence, deviation and deflection angles, relative eddy, rotating stall and Mach number are investigated. The relation between minimum relative Mach number of inducer and flow angle is investigated and it is observed that the minimum Mach number occurs for flow angle values between -680 and -520 . In the design, the effect of a 100 difference in flow angle is found to be less than 1 % on minimum relative Mach number.
The Cornell field-reversed ion ring experiment FIREX: experimental design and first results
International Nuclear Information System (INIS)
Podulka, W.J.; Greenly, J.B.; Anderson, D.E.; Glidden, S.C.; Hammer, D.A.; Omelchenko, Yu.A.; Sudan, R.N.
1996-01-01
The goal of FIREX (Field-reversed Ion Ring EXperiment) is to produce a fully field-reversed ring with 1 MeV protons. Such a ring requires about (2-3) x 10 17 protons, or 30-50 mC of charge. This charge is to be injected as an annular proton beam through a suitable magnetic cusp configuration to produce a compact ring. The critical design issues for the ion beam accelerator are described. First experimental results of ion diode operation indicate that the design is capable of producing the required beam parameters. (author). 4 figs., 4 refs
The Cornell field-reversed ion ring experiment FIREX: experimental design and first results
Energy Technology Data Exchange (ETDEWEB)
Podulka, W J; Greenly, J B; Anderson, D E; Glidden, S C; Hammer, D A; Omelchenko, Yu A; Sudan, R N [Cornell Univ., Ithaca, NY (United States). Laboratory of Plasma Studies
1997-12-31
The goal of FIREX (Field-reversed Ion Ring EXperiment) is to produce a fully field-reversed ring with 1 MeV protons. Such a ring requires about (2-3) x 10{sup 17} protons, or 30-50 mC of charge. This charge is to be injected as an annular proton beam through a suitable magnetic cusp configuration to produce a compact ring. The critical design issues for the ion beam accelerator are described. First experimental results of ion diode operation indicate that the design is capable of producing the required beam parameters. (author). 4 figs., 4 refs.
International Nuclear Information System (INIS)
Banks, H T; Davis, Jimena L; Ernstberger, Stacey L; Hu, Shuhua; Artimovich, Elena; Dhar, Arun K
2009-01-01
We discuss inverse problem results for problems involving the estimation of probability distributions using aggregate data for growth in populations. We begin with a mathematical model describing variability in the early growth process of size-structured shrimp populations and discuss a computational methodology for the design of experiments to validate the model and estimate the growth-rate distributions in shrimp populations. Parameter-estimation findings using experimental data from experiments so designed for shrimp populations cultivated at Advanced BioNutrition Corporation are presented, illustrating the usefulness of mathematical and statistical modeling in understanding the uncertainty in the growth dynamics of such populations
Zeqiri, F.; Alkan, M.; Kaya, B.; Toros, S.
2018-01-01
In this paper, the effects of cutting parameters on cutting forces and surface roughness based on Taguchi experimental design method are determined. Taguchi L9 orthogonal array is used to investigate the effects of machining parameters. Optimal cutting conditions are determined using the signal/noise (S/N) ratio which is calculated by average surface roughness and cutting force. Using results of analysis, effects of parameters on both average surface roughness and cutting forces are calculated on Minitab 17 using ANOVA method. The material that was investigated is Inconel 625 steel for two cases with heat treatment and without heat treatment. The predicted and calculated values with measurement are very close to each other. Confirmation test of results showed that the Taguchi method was very successful in the optimization of machining parameters for maximum surface roughness and cutting forces in the CNC turning process.
Experimental design research approaches, perspectives, applications
Stanković, Tino; Štorga, Mario
2016-01-01
This book presents a new, multidisciplinary perspective on and paradigm for integrative experimental design research. It addresses various perspectives on methods, analysis and overall research approach, and how they can be synthesized to advance understanding of design. It explores the foundations of experimental approaches and their utility in this domain, and brings together analytical approaches to promote an integrated understanding. The book also investigates where these approaches lead to and how they link design research more fully with other disciplines (e.g. psychology, cognition, sociology, computer science, management). Above all, the book emphasizes the integrative nature of design research in terms of the methods, theories, and units of study—from the individual to the organizational level. Although this approach offers many advantages, it has inherently led to a situation in current research practice where methods are diverging and integration between individual, team and organizational under...
Experimental and analytical determination of stability parameters for a balloon tethered in a wind
Redd, L. T.; Bennett, R. M.; Bland, S. R.
1973-01-01
Experimental and analytical techniques for determining stability parameters for a balloon tethered in a steady wind are described. These techniques are applied to a particular 7.64-meter-long balloon, and the results are presented. The stability parameters of interest appear as coefficients in linearized stability equations and are derived from the various forces and moments acting on the balloon. In several cases the results from the experimental and analytical techniques are compared and suggestions are given as to which techniques are the most practical means of determining values for the stability parameters.
Wang, Guang-yuan; Guan, Xin; Cao, Dong-jing; Tang, Shao-fan; Chen, Xiang; Liang, Lu; Zheng, Gang-tie
2017-11-01
requirement and the displacement restriction during launch are satisfied by tuning the nonlinear stiffness and damping parameters. A group of sample isolators are designed tested both statically and dynamically.
Optimizing incomplete sample designs for item response model parameters
van der Linden, Willem J.
Several models for optimizing incomplete sample designs with respect to information on the item parameters are presented. The following cases are considered: (1) known ability parameters; (2) unknown ability parameters; (3) item sets with multiple ability scales; and (4) response models with
Research on Parameter Design of Multi - axis Hydrostatic Transmission Vehicle
Directory of Open Access Journals (Sweden)
Zhao Liang
2017-01-01
Full Text Available In order to obtain reasonable parameters in the design of driving system of multi-axis hydrostatic transmission vehicle, the working principle of single-side drive of hydrostatic transmission vehicle is introduced. The matching and control of engine and hydraulic pump are analyzed. According to the driving equation of vehicle, The driving force required for driving system is determined, and the parameters of hydraulic motor, hydraulic pump, system working pressure and braking system are designed and calculated, which provides the parameter design for driving system of multi-axis hydrostatic transmission Reliable theoretical basis.
International Nuclear Information System (INIS)
Askari, Sima; Halladj, Rouein; Nazari, Mahdi
2013-01-01
Highlights: ► Sonochemical synthesis of SAPO-34 nanocrystals. ► Using Taguchi experimental design (L9) for optimizing the experimental procedure. ► The significant effects of all the ultrasonic parameters on the response. - Abstract: SAPO-34 nanocrystals with high crystallinity were synthesized by means of sonochemical method. An L9 orthogonal array of the Taguchi method was implemented to investigate the effects of sonication conditions on the preparation of SAPO-34 with respect to crystallinity of the final product phase. The experimental data establish the favorable phase crystallinity which is improved by increasing the ultrasonic power and the sonication temperature. In the case of ultrasonic irradiation time, however, an initial increases in crystallinity from 5 min to 15 min is followed by a decrease in crystallinity for longer sonication time
Directory of Open Access Journals (Sweden)
Douglas Domingues Bueno
2008-01-01
Full Text Available This paper deals with the study of algorithms for robust active vibration control in flexible structures considering uncertainties in system parameters. It became an area of enormous interest, mainly due to the countless demands of optimal performance in mechanical systems as aircraft, aerospace, and automotive structures. An important and difficult problem for designing active vibration control is to get a representative dynamic model. Generally, this model can be obtained using finite element method (FEM or an identification method using experimental data. Actuators and sensors may affect the dynamics properties of the structure, for instance, electromechanical coupling of piezoelectric material must be considered in FEM formulation for flexible and lightly damping structure. The nonlinearities and uncertainties involved in these structures make it a difficult task, mainly for complex structures as spatial truss structures. On the other hand, by using an identification method, it is possible to obtain the dynamic model represented through a state space realization considering this coupling. This paper proposes an experimental methodology for vibration control in a 3D truss structure using PZT wafer stacks and a robust control algorithm solved by linear matrix inequalities.
The reactor safety study of experimental multi-purpose VHTR design
International Nuclear Information System (INIS)
Yasuno, T.; Mitake, S.; Ezaki, M.; Suzuki, K.
1981-01-01
Over the past years, the design works of the Experimental Very High Temperature Reactor (VHTR) plant have been conducted at Japan Atomic Energy Research Institute. The conceptual design has been completed and the more detailed design works and the safety analysis of the experimental VHTR plant are continued. The purposes of design studies are to show the feasibility of the experimental VHTR program, to specify the characteristics and functions of the plant components, to point out the R and D items necessary for the experimental VHTR plant construction, and to analyze the feature of the plant safety. In this paper the summary of system design and safety features of the experimental reactor are indicated. Main issues are the safety philosophy for the design basis accident, the accidents assumed and the engineered safety systems adopted in the design works
Two polynomial representations of experimental design
Notari, Roberto; Riccomagno, Eva; Rogantin, Maria-Piera
2007-01-01
In the context of algebraic statistics an experimental design is described by a set of polynomials called the design ideal. This, in turn, is generated by finite sets of polynomials. Two types of generating sets are mostly used in the literature: Groebner bases and indicator functions. We briefly describe them both, how they are used in the analysis and planning of a design and how to switch between them. Examples include fractions of full factorial designs and designs for mixture experiments.
Procedure for statistical analysis of one-parameter discrepant experimental data
International Nuclear Information System (INIS)
Badikov, Sergey A.; Chechev, Valery P.
2012-01-01
A new, Mandel–Paule-type procedure for statistical processing of one-parameter discrepant experimental data is described. The procedure enables one to estimate a contribution of unrecognized experimental errors into the total experimental uncertainty as well as to include it in analysis. A definition of discrepant experimental data for an arbitrary number of measurements is introduced as an accompanying result. In the case of negligible unrecognized experimental errors, the procedure simply reduces to the calculation of the weighted average and its internal uncertainty. The procedure was applied to the statistical analysis of half-life experimental data; Mean half-lives for 20 actinides were calculated and results were compared to the ENSDF and DDEP evaluations. On the whole, the calculated half-lives are consistent with the ENSDF and DDEP evaluations. However, the uncertainties calculated in this work essentially exceed the ENSDF and DDEP evaluations for discrepant experimental data. This effect can be explained by adequately taking into account unrecognized experimental errors. - Highlights: ► A new statistical procedure for processing one-parametric discrepant experimental data has been presented. ► Procedure estimates a contribution of unrecognized errors in the total experimental uncertainty. ► Procedure was applied for processing half-life discrepant experimental data. ► Results of the calculations are compared to the ENSDF and DDEP evaluations.
Experimental evaluation of a modal parameter based system identification procedure
Yu, Minli; Feng, Ningsheng; Hahn, Eric J.
2016-02-01
Correct modelling of the foundation of a rotor bearing foundation system (RBFS) is an invaluable asset for the balancing and efficient running of turbomachinery. Numerical experiments have shown that a modal parameter based identification approach could be feasible for this purpose but there is a lack of experimental verification of the suitability of such a modal approach for even the simplest systems. In this paper the approach is tested on a simple experimental rig comprising a clamped horizontal bar with lumped masses. It is shown that apart from damping, the proposed approach can identify reasonably accurately the relevant modal parameters of the rig; and that the resulting equivalent system can predict reasonably well the frequency response of the rig. Hence, the proposed approach shows promise but further testing is required, since application to identifying the foundation of an RBFS involves the additional problem of accurately obtaining the force excitation from motion measurements.
International Nuclear Information System (INIS)
Maekawa, Fujio; Konno, Chikara; Kasugai, Yoshimi; Oyama, Yukio; Uno, Yoshitomo; Maekawa, Hiroshi; Ikeda, Yujiro
2000-01-01
As an R and D Task of shielding neutronics experiment under the Engineering Design Activities of the International Thermonuclear Experimental Reactor (ITER), streaming experiments with simulating a gap configuration formed by two neighboring blanket modules of ITER were carried out at the FNS (Fusion Neutron Source) facility. In this work, prediction capability of various nuclear design parameters was investigated through analysis of the experiments. The Monte Carlo transport calculation code MCNP-4A and the FENDL/E-1.0 and JENDL Fusion File cross section data libraries were used for the analysis with detailed modeling of the experimental conditions. As a result, all the measured quantities were reproduced within about ±30% by the calculations. It was concluded that these calculation tools were capable of predicting nuclear design parameters, such as helium production rates at connection legs of blanket modules to the back plate and nuclear responses in toroidal field coils, with uncertainty of ±30% for the geometry where gap-streaming effect was significant. (author)
DEFF Research Database (Denmark)
Chen, B. H.; Micheletti, M.; Baganz, F.
2009-01-01
-erythrulose. Experiments were performed using automated microwell studies at the 150 or 800 mu L scale. The derived kinetic parameters were then verified in a second round of experiments where model predictions showed excellent agreement with experimental data obtained under conditions not included in the original......Reliable models of enzyme kinetics are required for the effective design of bioconversion processes. Kinetic expressions of the enzyme-catalysed reaction rate however, are frequently complex and establishing accurate values of kinetic parameters normally requires a large number of experiments....... These can be both time consuming and expensive when working with the types of non-natural chiral intermediates important in pharmaceutical syntheses. This paper presents ail automated microscale approach to the rapid and cost effective generation of reliable kinetic models useful for bioconversion process...
A procedure for multi-objective optimization of tire design parameters
Nikola Korunović; Miloš Madić; Miroslav Trajanović; Miroslav Radovanović
2015-01-01
The identification of optimal tire design parameters for satisfying different requirements, i.e. tire performance characteristics, plays an essential role in tire design. In order to improve tire performance characteristics, formulation and solving of multi-objective optimization problem must be performed. This paper presents a multi-objective optimization procedure for determination of optimal tire design parameters for simultaneous minimization of strain energy density at two distinctive zo...
Experimental toxicology: Issues of statistics, experimental design, and replication.
Briner, Wayne; Kirwan, Jeral
2017-01-01
The difficulty of replicating experiments has drawn considerable attention. Issues with replication occur for a variety of reasons ranging from experimental design to laboratory errors to inappropriate statistical analysis. Here we review a variety of guidelines for statistical analysis, design, and execution of experiments in toxicology. In general, replication can be improved by using hypothesis driven experiments with adequate sample sizes, randomization, and blind data collection techniques. Copyright © 2016 Elsevier B.V. All rights reserved.
Thermal Hydraulic design parameters study for severe accidents using neural networks
Energy Technology Data Exchange (ETDEWEB)
Roh, Chang Hyun; Chang, Soon Heung [Korea Advanced Institute of Science and Technology, Taejon (Korea, Republic of); Chang, Keun Sun [Sunmoon University, Asan (Korea, Republic of)
1998-12-31
To provide the information on severe accident progression is very important for advanced or new type of nuclear power plant (NPP) design. A parametric study, therefore, was performed to investigate the effect of thermal hydraulic design parameters on severe accident progression of pressurized water reactors (PWRs). Nine parameters, which are considered important in NPP design or severe accident progression, were selected among the various thermal hydraulic design parameters. The backpropagation neural network (BPN) was used to determine parameters, which might more strongly affect the severe accident progression, among nine parameters. For training, different input patterns were generated by the latin hypercube sampling (LHS) technique and then different target patterns that contain core uncovery time and vessel failure time were obtained for Young Gwang Nuclear (YGN) Units 3 and 4 using modular accident analysis program (MAAP) 3.0B code. Three different severe accident scenarios, such as two loss of coolant accidents (LOCAs) and station blackout (SBO), were considered in this analysis. Results indicated that design parameters related to refueling water storage tank (RWST), accumulator and steam generator (S/G) have more dominant effects on the progression of severe accidents investigated, compared to the other six parameters. 9 refs., 5 tabs. (Author)
Thermal Hydraulic design parameters study for severe accidents using neural networks
Energy Technology Data Exchange (ETDEWEB)
Roh, Chang Hyun; Chang, Soon Heung [Korea Advanced Institute of Science and Technology, Taejon (Korea, Republic of); Chang, Keun Sun [Sunmoon University, Asan (Korea, Republic of)
1997-12-31
To provide the information on severe accident progression is very important for advanced or new type of nuclear power plant (NPP) design. A parametric study, therefore, was performed to investigate the effect of thermal hydraulic design parameters on severe accident progression of pressurized water reactors (PWRs). Nine parameters, which are considered important in NPP design or severe accident progression, were selected among the various thermal hydraulic design parameters. The backpropagation neural network (BPN) was used to determine parameters, which might more strongly affect the severe accident progression, among nine parameters. For training, different input patterns were generated by the latin hypercube sampling (LHS) technique and then different target patterns that contain core uncovery time and vessel failure time were obtained for Young Gwang Nuclear (YGN) Units 3 and 4 using modular accident analysis program (MAAP) 3.0B code. Three different severe accident scenarios, such as two loss of coolant accidents (LOCAs) and station blackout (SBO), were considered in this analysis. Results indicated that design parameters related to refueling water storage tank (RWST), accumulator and steam generator (S/G) have more dominant effects on the progression of severe accidents investigated, compared to the other six parameters. 9 refs., 5 tabs. (Author)
International Nuclear Information System (INIS)
Yunus Pamukoglu, M.; Mustafa Senyurt; Bulent Kirkan
2017-01-01
The biosorption of radioactive Th(IV) ions in the aqueous solutions onto the modified powdered waste sludge (MPWS) has been examined. In this context, the parameters affecting biosorption of Th(IV) from aqueous solutions has been examined by using MPWS biosorbent in Box Behnken statistical experimental design. The structure of MPWS biosorbent was characterized by using SEM and BET techniques. According to the experimental design results, MPWS and Th(IV) concentrations should be kept high to achieve the maximum efficiency in Th(IV) biosorption. On the other hand, MPWS, which is also used as a biosorbent, is an economical, effective and natural biosorbent. (author)
A drilling tool design and in situ identification of planetary regolith mechanical parameters
Zhang, Weiwei; Jiang, Shengyuan; Ji, Jie; Tang, Dewei
2018-05-01
The physical and mechanical properties as well as the heat flux of regolith are critical evidence in the study of planetary origin and evolution. Moreover, the mechanical properties of planetary regolith have great value for guiding future human planetary activities. For planetary subsurface exploration, an inchworm boring robot (IBR) has been proposed to penetrate the regolith, and the mechanical properties of the regolith are expected to be simultaneously investigated during the penetration process using the drilling tool on the IBR. This paper provides a preliminary study of an in situ method for measuring planetary regolith mechanical parameters using a drilling tool on a test bed. A conical-screw drilling tool was designed, and its drilling load characteristics were experimentally analyzed. Based on the drilling tool-regolith interaction model, two identification methods for determining the planetary regolith bearing and shearing parameters are proposed. The bearing and shearing parameters of lunar regolith simulant were successfully determined according to the pressure-sinkage tests and shear tests conducted on the test bed. The effects of the operating parameters on the identification results were also analyzed. The results indicate a feasible scheme for future planetary subsurface exploration.
International Nuclear Information System (INIS)
Henning, C.D.; Miller, J.R.
1988-01-01
The International Thermonuclear Experimental Reactor (ITER) is now completing a definition phase as a beginning of a three-year design effort. Preliminary parameters for the superconducting magnet system have been established to guide further and more detailed design work. Radiation tolerance of the superconductors and insulators has been of prime importance, since it sets requirements for the neutron-shield dimension and sensitively influences reactor size. The major levels of mechanical stress in the structure appear in the cases of the inboard legs of the toroidal-field (TF) coils. The cases of the poloidal-field (PF) coils must be made thin or segmented to minimize eddy current heating during inductive plasma operation. As a result, the winding packs of both the TF and PF coils includes significant fractions of steel. The TF winding pack provides support against in-plane separating loads but offers little support against out-of-plane loads, unless shear-bonding of the conductors can be maintained. The removal of heat due to nuclear and ac loads has not been a fundamental limit to design, but certainly has non-negligible economic consequences. We present here preliminary ITER magnet systems design parameters taken from trade studies, designs, and analyses performed by the Home Teams of the four ITER participants, by the ITER Magnet Design Unit in Garching, and by other participants at workshops organized by the Magnet Design Unit. The work presented here reflects the efforts of many, but the responsibility for the opinions expressed is the authors'. 4 refs., 3 figs., 4 tabs
Linear parameter varying representations for nonlinear control design
Carter, Lance Huntington
Linear parameter varying (LPV) systems are investigated as a framework for gain-scheduled control design and optimal hybrid control. An LPV system is defined as a linear system whose dynamics depend upon an a priori unknown but measurable exogenous parameter. A gain-scheduled autopilot design is presented for a bank-to-turn (BTT) missile. The method is novel in that the gain-scheduled design does not involve linearizations about operating points. Instead, the missile dynamics are brought to LPV form via a state transformation. This idea is applied to the design of a coupled longitudinal/lateral BTT missile autopilot. The pitch and yaw/roll dynamics are separately transformed to LPV form, where the cross axis states are treated as "exogenous" parameters. These are actually endogenous variables, so such a plant is called "quasi-LPV." Once in quasi-LPV form, a family of robust controllers using mu synthesis is designed for both the pitch and yaw/roll channels, using angle-of-attack and roll rate as the scheduling variables. The closed-loop time response is simulated using the original nonlinear model and also using perturbed aerodynamic coefficients. Modeling and control of engine idle speed is investigated using LPV methods. It is shown how generalized discrete nonlinear systems may be transformed into quasi-LPV form. A discrete nonlinear engine model is developed and expressed in quasi-LPV form with engine speed as the scheduling variable. An example control design is presented using linear quadratic methods. Simulations are shown comparing the LPV based controller performance to that using PID control. LPV representations are also shown to provide a setting for hybrid systems. A hybrid system is characterized by control inputs consisting of both analog signals and discrete actions. A solution is derived for the optimal control of hybrid systems with generalized cost functions. This is shown to be computationally intensive, so a suboptimal strategy is proposed that
Optimization Design of Multi-Parameters in Rail Launcher System
Directory of Open Access Journals (Sweden)
Yujiao Zhang
2014-05-01
Full Text Available Today the energy storage systems are still encumbering, therefore it is useful to think about the optimization of a railgun system in order to achieve the best performance with the lowest energy input. In this paper, an optimal design method considering 5 parameters is proposed to improve the energy conversion efficiency of a simple railgun. In order to avoid costly trials, the field- circuit method is employed to analyze the operations of different structural railguns with different parameters respectively. And the orthogonal test approach is used to guide the simulation for choosing the better parameter combinations, as well reduce the calculation cost. The research shows that the proposed method gives a better result in the energy efficiency of the system. To improve the energy conversion efficiency of electromagnetic rail launchers, the selection of more parameters must be considered in the design stage, such as the width, height and length of rail, the distance between rail pair, and pulse forming inductance. However, the relationship between these parameters and energy conversion efficiency cannot be directly described by one mathematical expression. So optimization methods must be applied to conduct design. In this paper, a rail launcher with five parameters was optimized by using orthogonal test method. According to the arrangement of orthogonal table, the better parameters’ combination can be obtained through less calculation. Under the condition of different parameters’ value, field and circuit simulation analysis were made. The results show that the energy conversion efficiency of the system is increased by 71.9 % after parameters optimization.
Witono, J. R.; Noordergraaf, I. W.; Heeres, H. J.; Janssen, L. P. B. M.
2012-01-01
The graft copolymerization of cassava starch with acrylic acid was investigated using a free radical initiator system (Fe2+/H2O2 redox system) in water. A comprehensive understanding of the important variables and their interaction has been obtained by applying an experimental design method. In this
Community Design Parameters and the Performance of Residential Cogeneration Systems
Directory of Open Access Journals (Sweden)
Hazem Rashed-Ali
2012-11-01
Full Text Available The integration of cogeneration systems in residential and mixed-use communities has the potential of reducing their energy demand and harmful emissions and can thus play asignificant role in increasing their environmental sustainability. This study investigated the impact of selected planning and architectural design parameters on the environmental and economic performances of centralized cogeneration systems integrated into residential communities in U.S.cold climates. Parameters investigated include: 1 density, 2 use mix, 3 street configuration, 4 housing typology, 5 envelope and building systems’ efficiencies, and 6 passive solar energyutilization. The study integrated several simulation tools into a procedure to assess the impact of each design parameter on the cogeneration system performance. This assessment procedure included: developing a base-line model representing typical design characteristics of U.S. residential communities; assessing the cogeneration system’s performance within this model using three performance indicators: percentage of reduction in primary energy use, percentage of reduction in CO2 emissions; and internal rate of return; assessing the impact of each parameter on the system performance through developing 46 design variations of the base-line model representing potential changes in each parameter and calculating the three indicators for each variation; and finally, using a multi-attribute decision analysis methodology to evaluate the relative impact of each parameter on the cogeneration system performance. The study results show that planning parameters had a higher impact on the cogeneration system performance than architectural ones. Also, a significant correlation was found between design characteristics identified as favorable for the cogeneration system performance and those of sustainable residential communities. These include high densities, high use mix, interconnected street networks, and mixing of
Theoretical and experimental determination of K - and L -shell x-ray relaxation parameters in Ni
Guerra, M.; Sampaio, J. M.; Parente, F.; Indelicato, P.; Hönicke, P.; Müller, M.; Beckhoff, B.; Marques, J. P.; Santos, J. P.
2018-04-01
Fluorescence yields (FY) for the Ni K and L shells were determined by a theoretical and an experimental group within the framework of the International Initiative on X-ray Fundamental Parameters (FPs) collaboration. Coster-Kronig (CK) parameters were also measured for the L shell of Ni. Theoretical calculations of the same parameters were performed using the Dirac-Fock method, including relativistic and QED corrections. The experimental values for the FY and CK were determined at the PTB laboratory in the synchrotron radiation facility BESSY II, Berlin, Germany, and are compared to the corresponding calculated values.
Sánchez, M S; Sarabia, L A; Ortiz, M C
2012-11-19
Experimental designs for a given task should be selected on the base of the problem being solved and of some criteria that measure their quality. There are several such criteria because there are several aspects to be taken into account when making a choice. The most used criteria are probably the so-called alphabetical optimality criteria (for example, the A-, E-, and D-criteria related to the joint estimation of the coefficients, or the I- and G-criteria related to the prediction variance). Selecting a proper design to solve a problem implies finding a balance among these several criteria that measure the performance of the design in different aspects. Technically this is a problem of multi-criteria optimization, which can be tackled from different views. The approach presented here addresses the problem in its real vector nature, so that ad hoc experimental designs are generated with an algorithm based on evolutionary algorithms to find the Pareto-optimal front. There is not theoretical limit to the number of criteria that can be studied and, contrary to other approaches, no just one experimental design is computed but a set of experimental designs all of them with the property of being Pareto-optimal in the criteria needed by the user. Besides, the use of an evolutionary algorithm makes it possible to search in both continuous and discrete domains and avoid the need of having a set of candidate points, usual in exchange algorithms. Copyright © 2012 Elsevier B.V. All rights reserved.
Physics design of experimental metal fuelled fast reactor cores for full scale demonstration
International Nuclear Information System (INIS)
Devan, K.; Bachchan, Abhitab; Riyas, A.; Sathiyasheela, T.; Mohanakrishnan, P.; Chetal, S.C.
2011-01-01
Highlights: → In this study we made physics designs of experimental metal fast reactor cores. → Aim is for full-scale demonstration of fuel assemblies in a commercial power reactor. → Minimum power with adequate safety is considered. → In addition, fuel sustainability is also considered in the design. → Sodium bonded U-Pu-6%Zr and mechanically bonded U-Pu alloys are used. - Abstract: Fast breeder reactors based on metal fuel are planned to be in operation for the year beyond 2025 to meet the growing energy demand in India. A road map is laid towards the development of technologies required for launching 1000 MWe commercial metal breeder reactors with closed fuel cycle. Construction of a test reactor with metallic fuel is also envisaged to provide full-scale testing of fuel sub-assemblies planned for a commercial power reactor. Physics design studies have been carried out to arrive at a core configuration for this experimental facility. The aim of this study is to find out minimum power of the core to meet the requirements of safety as well as full-scale demonstration. In addition, fuel sustainability is also a consideration in the design. Two types of metallic fuel pins, viz. a sodium bonded ternary (U-Pu-6% Zr) alloy and a mechanically bonded binary (U-Pu) alloy with 125 μm thickness zirconium liner, are considered for this study. Using the European fast reactor neutronics code system, ERANOS 2.1, four metallic fast reactor cores are optimized and estimated their important steady state parameters. The ABBN-93 system is also used for estimating the important safety parameters. Minimum achievable power from the converter metallic core is 220 MWt. A 320 MWt self-sustaining breeder metal core is recommended for the test facility.
A Laplace method for under-determined Bayesian optimal experimental designs
Long, Quan
2014-12-17
In Long et al. (2013), a new method based on the Laplace approximation was developed to accelerate the estimation of the post-experimental expected information gains (Kullback–Leibler divergence) in model parameters and predictive quantities of interest in the Bayesian framework. A closed-form asymptotic approximation of the inner integral and the order of the corresponding dominant error term were obtained in the cases where the parameters are determined by the experiment. In this work, we extend that method to the general case where the model parameters cannot be determined completely by the data from the proposed experiments. We carry out the Laplace approximations in the directions orthogonal to the null space of the Jacobian matrix of the data model with respect to the parameters, so that the information gain can be reduced to an integration against the marginal density of the transformed parameters that are not determined by the experiments. Furthermore, the expected information gain can be approximated by an integration over the prior, where the integrand is a function of the posterior covariance matrix projected over the aforementioned orthogonal directions. To deal with the issue of dimensionality in a complex problem, we use either Monte Carlo sampling or sparse quadratures for the integration over the prior probability density function, depending on the regularity of the integrand function. We demonstrate the accuracy, efficiency and robustness of the proposed method via several nonlinear under-determined test cases. They include the designs of the scalar parameter in a one dimensional cubic polynomial function with two unidentifiable parameters forming a linear manifold, and the boundary source locations for impedance tomography in a square domain, where the unknown parameter is the conductivity, which is represented as a random field.
Design parameters and source terms: Volume 3, Source terms
International Nuclear Information System (INIS)
1987-10-01
The Design Parameters and Source Terms Document was prepared in accordance with DOE request and to provide data for the environmental impact study to be performed in the future for the Deaf Smith County, Texas site for a nuclear waste repository in salt. This document updates a previous unpublished report by Stearns Catalytic Corporation (SCC), entitled ''Design Parameters and Source Terms for a Two-Phase Repository in Salt,'' 1985, to the level of the Site Characterization Plan - Conceptual Design Report. The previous unpublished SCC Study identifies the data needs for the Environmental Assessment effort for seven possible Salt Repository sites. 11 refs., 9 tabs
Sohn, Jung Woo; Jeon, Juncheol; Nguyen, Quoc Hung; Choi, Seung-Bok
2015-08-01
In this paper, a disc-type magneto-rheological (MR) brake is designed for a mid-sized motorcycle and its performance is experimentally evaluated. The proposed MR brake consists of an outer housing, a rotating disc immersed in MR fluid, and a copper wire coiled around a bobbin to generate a magnetic field. The structural configuration of the MR brake is first presented with consideration of the installation space for the conventional hydraulic brake of a mid-sized motorcycle. The design parameters of the proposed MR brake are optimized to satisfy design requirements such as the braking torque, total mass of the MR brake, and cruising temperature caused by the magnetic-field friction of the MR fluid. In the optimization procedure, the braking torque is calculated based on the Herschel-Bulkley rheological model, which predicts MR fluid behavior well at high shear rate. An optimization tool based on finite element analysis is used to obtain the optimized dimensions of the MR brake. After manufacturing the MR brake, mechanical performances regarding the response time, braking torque and cruising temperature are experimentally evaluated.
Back up core designs for the experimental multi-purpose VHTR
International Nuclear Information System (INIS)
Aochi, Tetsuo; Yasuno, Takehiko; Miyamoto, Yoshiaki; Shindo, Ryuichi; Ikushima, Takeshi
1979-02-01
For the Experimental Multi-Purpose Very High Temperature Reactor (thermal power 50 MW and reactor outlet helium temperature 1000 0 C), design studies have been made of two backup cores loaded with new-type fuel elements. The purpose is to improve core operational characteristics, especially in thermohydraulics, of the reference design core consisting of pin-in-block type fuel elements having externally cooled hollow fuel rods. In this report are described the design principles and the analyses made of nuclear, thermal and hydraulic, fuel, and safety performances to determine the backup fuel and core design parameters. The first backup core (SP fuel core) is composed of fuel elements with internally cooled fuel rods (semi-pin), 36 rods in each standard element and 18 rods in each control element. The second backup core (MH fuel core) is composed of multihole fuel elements. 102 fuel and 54 coolant holes in each standard element and 30 fuel and 18 coolant holes in each control element. Either of the cores has 73 fuel columns 4 m high; the arrangement of active core and reactor internal structures is the same as that in the reference design. The backup cores meet nearly all design requirements of the VHTR, permitting the rated power operation with coolant Reynolds number of over 10,000 in the SP core and over 6,000 in the MH core. (author)
[Design of blood-pressure parameter auto-acquisition circuit].
Chen, Y P; Zhang, D L; Bai, H W; Zhang, D A
2000-02-01
This paper presents the realization and design of a kind of blood-pressure parameter auto-acquisition circuit. The auto-acquisition of blood-pressure parameter controlled by 89C2051 single chip microcomputer is accomplished by collecting and processing the driving signal of LCD. The circuit that is successfully applied in the home unit of telemedicine system has the simple and reliable properties.
Fisher information and Cramér-Rao lower bound for experimental design in parallel imaging.
Bouhrara, Mustapha; Spencer, Richard G
2018-06-01
The Cramér-Rao lower bound (CRLB) is widely used in the design of magnetic resonance (MR) experiments for parameter estimation. Previous work has considered only Gaussian or Rician noise distributions in this calculation. However, the noise distribution for multi-coil acquisitions, such as in parallel imaging, obeys the noncentral χ-distribution under many circumstances. The purpose of this paper is to present the CRLB calculation for parameter estimation from multi-coil acquisitions. We perform explicit calculations of Fisher matrix elements and the associated CRLB for noise distributions following the noncentral χ-distribution. The special case of diffusion kurtosis is examined as an important example. For comparison with analytic results, Monte Carlo (MC) simulations were conducted to evaluate experimental minimum standard deviations (SDs) in the estimation of diffusion kurtosis model parameters. Results were obtained for a range of signal-to-noise ratios (SNRs), and for both the conventional case of Gaussian noise distribution and noncentral χ-distribution with different numbers of coils, m. At low-to-moderate SNR, the noncentral χ-distribution deviates substantially from the Gaussian distribution. Our results indicate that this departure is more pronounced for larger values of m. As expected, the minimum SDs (i.e., CRLB) in derived diffusion kurtosis model parameters assuming a noncentral χ-distribution provided a closer match to the MC simulations as compared to the Gaussian results. Estimates of minimum variance for parameter estimation and experimental design provided by the CRLB must account for the noncentral χ-distribution of noise in multi-coil acquisitions, especially in the low-to-moderate SNR regime. Magn Reson Med 79:3249-3255, 2018. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.
Consistent Stochastic Modelling of Meteocean Design Parameters
DEFF Research Database (Denmark)
Sørensen, John Dalsgaard; Sterndorff, M. J.
2000-01-01
Consistent stochastic models of metocean design parameters and their directional dependencies are essential for reliability assessment of offshore structures. In this paper a stochastic model for the annual maximum values of the significant wave height, and the associated wind velocity, current...
Sahoo, C; Gupta, A K
2012-05-15
Photocatalytic degradation of methyl blue (MYB) was studied using Ag(+) doped TiO(2) under UV irradiation in a batch reactor. Catalytic dose, initial concentration of dye and pH of the reaction mixture were found to influence the degradation process most. The degradation was found to be effective in the range catalytic dose (0.5-1.5g/L), initial dye concentration (25-100ppm) and pH of reaction mixture (5-9). Using the three factors three levels Box-Behnken design of experiment technique 15 sets of experiments were designed considering the effective ranges of the influential parameters. The results of the experiments were fitted to two quadratic polynomial models developed using response surface methodology (RSM), representing functional relationship between the decolorization and mineralization of MYB and the experimental parameters. Design Expert software version 8.0.6.1 was used to optimize the effects of the experimental parameters on the responses. The optimum values of the parameters were dose of Ag(+) doped TiO(2) 0.99g/L, initial concentration of MYB 57.68ppm and pH of reaction mixture 7.76. Under the optimal condition the predicted decolorization and mineralization rate of MYB were 95.97% and 80.33%, respectively. Regression analysis with R(2) values >0.99 showed goodness of fit of the experimental results with predicted values. Copyright © 2012 Elsevier B.V. All rights reserved.
Validation of a buffet meal design in an experimental restaurant.
Allirot, Xavier; Saulais, Laure; Disse, Emmanuel; Roth, Hubert; Cazal, Camille; Laville, Martine
2012-06-01
We assessed the reproducibility of intakes and meal mechanics parameters (cumulative energy intake (CEI), number of bites, bite rate, mean energy content per bite) during a buffet meal designed in a natural setting, and their sensitivity to food deprivation. Fourteen men were invited to three lunch sessions in an experimental restaurant. Subjects ate their regular breakfast before sessions A and B. They skipped breakfast before session FAST. The same ad libitum buffet was offered each time. Energy intakes and meal mechanics were assessed by foods weighing and video recording. Intrasubject reproducibility was evaluated by determining intraclass correlation coefficients (ICC). Mixed-models were used to assess the effects of the sessions on CEI. We found a good reproducibility between A and B for total energy (ICC=0.82), carbohydrate (ICC=0.83), lipid (ICC=0.81) and protein intake (ICC=0.79) and for meal mechanics parameters. Total energy, lipid and carbohydrate intake were higher in FAST than in A and B. CEI were found sensitive to differences in hunger level while the other meal mechanics parameters were stable between sessions. In conclusion, a buffet meal in a normal eating environment is a valid tool for assessing the effects of interventions on intakes. Copyright © 2012 Elsevier Ltd. All rights reserved.
Sensitivity of seismic design parameters to input variables
International Nuclear Information System (INIS)
Wium, D.J.W.
1987-01-01
The probabilistic method introduced by Cornell (1968) has been used to a large extent for this purpose. Due to its probabilistic approach, this technique provides a sound basis for studying the influence of the dominant parameters in such a model. Although the Southern African region is not well known for its seismicity, a number of events in the recent past has focussed the attention on some seismically active areas where special attention may be needed in defining the correct design parameters. The relatively sparse historical seismic data has been used to develop a mathematical model which represents this region. This paper briefly discusses this model, and uses it as a basis for evaluating the influence of the uncertainty in each of the principal parameters, being the seismicity of the region, the attenuation of seismic waves after an event, and models that can be used to arrive at engineering design values. (orig./HP)
Directory of Open Access Journals (Sweden)
Ajinath Eknath Shirsat
2015-01-01
Full Text Available The purpose of present study was to optimize rizatriptan (RZT chitosan (CS nanoparticles using ionic gelation method by application of quality by design (QbD approach. Based on risk assessment, effect of three variables, that is CS %, tripolyphosphate % and stirring speed were studied on critical quality attributes (CQAs; particle size and entrapment efficiency. Central composite design (CCD was implemented for design of experimentation with 20 runs. RZT CS nanoparticles were characterized for particle size, polydispersity index, entrapment efficiency, in-vitro release study, differential scanning calorimetric, X-ray diffraction, scanning electron microscopy (SEM. Based on QbD approach, design space (DS was optimized with a combination of selected variables with entrapment efficiency > 50% w/w and a particle size between 400 and 600 nm. Validation of model was performed with 3 representative formulations from DS for which standard error of − 0.70-3.29 was observed between experimental and predicted values. In-vitro drug release followed initial burst release 20.26 ± 2.34% in 3-4 h with sustained drug release of 98.43 ± 2.45% in 60 h. Lower magnitude of standard error for CQAs confirms the validation of selected CCD model for optimization of RZT CS nanoparticles. In-vitro drug release followed dual mechanism via, diffusion and polymer erosion. RZT CS nanoparticles were prepared successfully using QbD approach with the understanding of the high risk process and formulation parameters involved and optimized DS with a multifactorial combination of critical parameters to obtain predetermined RZT loaded CS nanoparticle specifications.
Energy Technology Data Exchange (ETDEWEB)
Sahoo, C. [Environmental Engineering Division, Department of Civil Engineering, Indian Institute of Technology, Kharagpur, 721302 (India); Gupta, A.K., E-mail: agupta@civil.iitkgp.ernet.in [Environmental Engineering Division, Department of Civil Engineering, Indian Institute of Technology, Kharagpur, 721302 (India)
2012-05-15
Highlights: Black-Right-Pointing-Pointer Optimization of color removal and COD removal done by response surface approach. Black-Right-Pointing-Pointer The experiments were designed using Box-Behnken spherical design. Black-Right-Pointing-Pointer Two quadratic polynomial models were developed for the responses. Black-Right-Pointing-Pointer Single point numerical optimization was done considering three constraints. Black-Right-Pointing-Pointer Validation by performing the experiment under optimized conditions. - Abstract: Photocatalytic degradation of methyl blue (MYB) was studied using Ag{sup +} doped TiO{sub 2} under UV irradiation in a batch reactor. Catalytic dose, initial concentration of dye and pH of the reaction mixture were found to influence the degradation process most. The degradation was found to be effective in the range catalytic dose (0.5-1.5 g/L), initial dye concentration (25-100 ppm) and pH of reaction mixture (5-9). Using the three factors three levels Box-Behnken design of experiment technique 15 sets of experiments were designed considering the effective ranges of the influential parameters. The results of the experiments were fitted to two quadratic polynomial models developed using response surface methodology (RSM), representing functional relationship between the decolorization and mineralization of MYB and the experimental parameters. Design Expert software version 8.0.6.1 was used to optimize the effects of the experimental parameters on the responses. The optimum values of the parameters were dose of Ag{sup +} doped TiO{sub 2} 0.99 g/L, initial concentration of MYB 57.68 ppm and pH of reaction mixture 7.76. Under the optimal condition the predicted decolorization and mineralization rate of MYB were 95.97% and 80.33%, respectively. Regression analysis with R{sup 2} values >0.99 showed goodness of fit of the experimental results with predicted values.
International Nuclear Information System (INIS)
Sahoo, C.; Gupta, A.K.
2012-01-01
Highlights: ► Optimization of color removal and COD removal done by response surface approach. ► The experiments were designed using Box–Behnken spherical design. ► Two quadratic polynomial models were developed for the responses. ► Single point numerical optimization was done considering three constraints. ► Validation by performing the experiment under optimized conditions. - Abstract: Photocatalytic degradation of methyl blue (MYB) was studied using Ag + doped TiO 2 under UV irradiation in a batch reactor. Catalytic dose, initial concentration of dye and pH of the reaction mixture were found to influence the degradation process most. The degradation was found to be effective in the range catalytic dose (0.5–1.5 g/L), initial dye concentration (25–100 ppm) and pH of reaction mixture (5–9). Using the three factors three levels Box–Behnken design of experiment technique 15 sets of experiments were designed considering the effective ranges of the influential parameters. The results of the experiments were fitted to two quadratic polynomial models developed using response surface methodology (RSM), representing functional relationship between the decolorization and mineralization of MYB and the experimental parameters. Design Expert software version 8.0.6.1 was used to optimize the effects of the experimental parameters on the responses. The optimum values of the parameters were dose of Ag + doped TiO 2 0.99 g/L, initial concentration of MYB 57.68 ppm and pH of reaction mixture 7.76. Under the optimal condition the predicted decolorization and mineralization rate of MYB were 95.97% and 80.33%, respectively. Regression analysis with R 2 values >0.99 showed goodness of fit of the experimental results with predicted values.
Experimental design for optimizing MALDI-TOF-MS analysis of palladium complexes
Directory of Open Access Journals (Sweden)
Rakić-Kostić Tijana M.
2017-01-01
Full Text Available This paper presents optimization of matrix-assisted laser desorption/ionization (MALDI time-of-flight (TOF mass spectrometer (MS instrumental parameters for the analysis of chloro(2,2'',2"-terpyridinepalladium(II chloride dihydrate complex applying design of experiments methodology (DoE. This complex is of interest for potential use in the cancer therapy. DoE methodology was proved to succeed in optimization of many complex analytical problems. However, it has been poorly used for MALDI-TOF-MS optimization up to now. The theoretical mathematical relationships which explain the influence of important experimental factors (laser energy, grid voltage and number of laser shots on the selected responses (signal to noise – S/N ratio and the resolution – R of the leading peak is established. The optimal instrumental settings providing maximal S/N and R are identified and experimentally verified. [Project of the Serbian Ministry of Education, Science and Technological Development, Grant no. 172052 and Grant no. 172011
Efficient Bayesian experimental design for contaminant source identification
Zhang, Jiangjiang; Zeng, Lingzao; Chen, Cheng; Chen, Dingjiang; Wu, Laosheng
2015-01-01
In this study, an efficient full Bayesian approach is developed for the optimal sampling well location design and source parameters identification of groundwater contaminants. An information measure, i.e., the relative entropy, is employed to quantify the information gain from concentration measurements in identifying unknown parameters. In this approach, the sampling locations that give the maximum expected relative entropy are selected as the optimal design. After the sampling locations are determined, a Bayesian approach based on Markov Chain Monte Carlo (MCMC) is used to estimate unknown parameters. In both the design and estimation, the contaminant transport equation is required to be solved many times to evaluate the likelihood. To reduce the computational burden, an interpolation method based on the adaptive sparse grid is utilized to construct a surrogate for the contaminant transport equation. The approximated likelihood can be evaluated directly from the surrogate, which greatly accelerates the design and estimation process. The accuracy and efficiency of our approach are demonstrated through numerical case studies. It is shown that the methods can be used to assist in both single sampling location and monitoring network design for contaminant source identifications in groundwater.
Schweizer, Marin L; Braun, Barbara I; Milstone, Aaron M
2016-10-01
Quasi-experimental studies evaluate the association between an intervention and an outcome using experiments in which the intervention is not randomly assigned. Quasi-experimental studies are often used to evaluate rapid responses to outbreaks or other patient safety problems requiring prompt, nonrandomized interventions. Quasi-experimental studies can be categorized into 3 major types: interrupted time-series designs, designs with control groups, and designs without control groups. This methods paper highlights key considerations for quasi-experimental studies in healthcare epidemiology and antimicrobial stewardship, including study design and analytic approaches to avoid selection bias and other common pitfalls of quasi-experimental studies. Infect Control Hosp Epidemiol 2016;1-6.
International Nuclear Information System (INIS)
Dotta, A.L.B.; Costa, C.A.; Farias, M.C.M.; Cunha, M.A da
2016-01-01
This work represents the tribological study of Al_2O_3 obtained by LPIM using the experimental design technique to evaluate the interaction of the tribological parameters with the friction and wear. The LPIM process was performed at 90 °C for 24 h. The average friction coefficient for the factorial experimental design varied significantly with the load and the speed when Al_2O_3 was tested with the steel counter body. In general, the wear coefficient was lower for the tribological pair Al_2O_3-steel, in which occurred the formation of an iron oxide tribofilm on the surface. As for the Al_2O_3-Al_2O_3 pair, an intergranular fracture of the surface occurred, in addition to the presence of material adhered on the tracks. (author)
Experimental design: Case studies of diagnostics optimization for W7-X
International Nuclear Information System (INIS)
Dreier, H.; Dinklage, A.; Fischer, R.; Hartfuss, H.-J.; Hirsch, M.; Kornejew, P.; Pasch, E.; Turkin, Yu.
2005-01-01
The preparation of diagnostics for Wendelstein 7-X is accompanied by diagnostics simulations and optimization. Starting from the physical objectives, the design of diagnostics should incorporate predictive modelling (e.g. transport modelling) and simulations of respective measurements. Although technical constraints are governing design considerations, it appears that several design parameters of different diagnostics can be optimized. However, a general formulation for fusion diagnostics design in terms of optimization is lacking. In this paper, first case studies of Bayesian experimental design aiming at applications on W7-X diagnostics preparation are presented. The information gain of a measurement is formulated as a utility function which is expressed in terms of the Kullback-Leibler divergence. Then, the expected range of data is to be included and the resulting expected utility represents the objective for optimization. Bayesian probability theory gives a framework allowing us for an appropriate formulation of the design problem in terms of probability distribution functions. Results are obtained for the information gain from interferometry and for the design of polychromators for Thomson scattering. For interferometry, studies of the choice of line-of-sights for optimum signal and for the reproduction of gradient positions are presented for circular, elliptical and W7-X geometries. For Thomson scattering, the design of filter transmissions for density and temperature measurements are discussed. (author)
Experimental study of lithium free-surface flow for IFMIF target design
International Nuclear Information System (INIS)
Kondo, H.; Fujisato, A.; Yamaoka, N.; Inoue, S.; Miyamoto, S.; Iida, T.; Nakamura, H.; Ida, M.; Matushita, I.; Muroga, T.; Horiike, H.
2006-01-01
Lithium free-surface flow experiments to verify the design of IFMIF target have been carried out at Osaka University. The present report summarizes experimental results of surface phenomena, and cavitation characteristics of the loop, so as to try to apply these results to design parameters. Waves on the lithium flow surface is similar to that on water, and can be predicted by a linear stability theory. The wave amplitude is measured by an electro-contact probe. Surface roughness on a target nozzle, caused for example by attached chemical compounds and/or wastages by erosion and corrosion, can lead to a significant loss of target flow stability as well as surface wakes. The need of a polishing manipulator or exchange of the nozzle may be anticipated. Cavitation characteristic of the loop was measured by an accelerometer. From the results, a friction factor could be estimated fort he lithium flow
Robust Bayesian Experimental Design for Conceptual Model Discrimination
Pham, H. V.; Tsai, F. T. C.
2015-12-01
A robust Bayesian optimal experimental design under uncertainty is presented to provide firm information for model discrimination, given the least number of pumping wells and observation wells. Firm information is the maximum information of a system can be guaranteed from an experimental design. The design is based on the Box-Hill expected entropy decrease (EED) before and after the experiment design and the Bayesian model averaging (BMA) framework. A max-min programming is introduced to choose the robust design that maximizes the minimal Box-Hill EED subject to that the highest expected posterior model probability satisfies a desired probability threshold. The EED is calculated by the Gauss-Hermite quadrature. The BMA method is used to predict future observations and to quantify future observation uncertainty arising from conceptual and parametric uncertainties in calculating EED. Monte Carlo approach is adopted to quantify the uncertainty in the posterior model probabilities. The optimal experimental design is tested by a synthetic 5-layer anisotropic confined aquifer. Nine conceptual groundwater models are constructed due to uncertain geological architecture and boundary condition. High-performance computing is used to enumerate all possible design solutions in order to identify the most plausible groundwater model. Results highlight the impacts of scedasticity in future observation data as well as uncertainty sources on potential pumping and observation locations.
Intelligent design of mechanical parameters of the joint in vehicle body concept design model
Hou, Wen-bin; Zhang, Hong-zhe; Hou, Da-jun; Hu, Ping
2013-05-01
In order to estimate the mechanical properties of the overall structure of the body accurately and quickly in conceptual design phase of the body, the beam and shell mixing elements was used to build simplified finite element model of the body. Through the BP neural network algorithm, the parameters of the mechanical property of joints element which had more affection on calculation accuracy were calculated and the joint finite element model based on the parameters was also constructed. The case shown that the method can improve the accuracy of the vehicle simulation results, while not too many design details were needed, which was fit to the demand in the vehicle body conceptual design phase.
Revised design for the Tokamak experimental power reactor
International Nuclear Information System (INIS)
Stacey, W.M. Jr.; Abdou, M.A.; Brooks, J.N.
1977-03-01
A new, preliminary design has been identified for the tokamak experimental power reactor (EPR). The revised EPR design is simpler, more compact, less expensive and has somewhat better performance characteristics than the previous design, yet retains many of the previously developed design concepts. This report summarizes the principle features of the new EPR design, including performance and cost
Experimental design matters for statistical analysis
DEFF Research Database (Denmark)
Jensen, Signe Marie; Schaarschmidt, Frank; Onofri, Andrea
2018-01-01
, the experimental design is often more or less neglected when analyzing data. Two data examples were analyzed using different modelling strategies: Firstly, in a randomized complete block design, mean heights of maize treated with a herbicide and one of several adjuvants were compared. Secondly, translocation...... of an insecticide applied to maize as a seed treatment was evaluated using incomplete data from an unbalanced design with several layers of hierarchical sampling. Extensive simulations were carried out to further substantiate the effects of different modelling strategies. RESULTS: It was shown that results from sub...
Issues and recent advances in optimal experimental design for site investigation (Invited)
Nowak, W.
2013-12-01
This presentation provides an overview over issues and recent advances in model-based experimental design for site exploration. The addressed issues and advances are (1) how to provide an adequate envelope to prior uncertainty, (2) how to define the information needs in a task-oriented manner, (3) how to measure the expected impact of a data set that it not yet available but only planned to be collected, and (4) how to perform best the optimization of the data collection plan. Among other shortcomings of the state-of-the-art, it is identified that there is a lack of demonstrator studies where exploration schemes based on expert judgment are compared to exploration schemes obtained by optimal experimental design. Such studies will be necessary do address the often voiced concern that experimental design is an academic exercise with little improvement potential over the well- trained gut feeling of field experts. When addressing this concern, a specific focus has to be given to uncertainty in model structure, parameterizations and parameter values, and to related surprises that data often bring about in field studies, but never in synthetic-data based studies. The background of this concern is that, initially, conceptual uncertainty may be so large that surprises are the rule rather than the exception. In such situations, field experts have a large body of experience in handling the surprises, and expert judgment may be good enough compared to meticulous optimization based on a model that is about to be falsified by the incoming data. In order to meet surprises accordingly and adapt to them, there needs to be a sufficient representation of conceptual uncertainty within the models used. Also, it is useless to optimize an entire design under this initial range of uncertainty. Thus, the goal setting of the optimization should include the objective to reduce conceptual uncertainty. A possible way out is to upgrade experimental design theory towards real-time interaction
Development of the Biological Experimental Design Concept Inventory (BEDCI)
Deane, Thomas; Nomme, Kathy; Jeffery, Erica; Pollock, Carol; Birol, Gulnur
2014-01-01
Interest in student conception of experimentation inspired the development of a fully validated 14-question inventory on experimental design in biology (BEDCI) by following established best practices in concept inventory (CI) design. This CI can be used to diagnose specific examples of non-expert-like thinking in students and to evaluate the…
Energy Technology Data Exchange (ETDEWEB)
Marzouk, Youssef [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)
2016-08-31
Predictive simulation of complex physical systems increasingly rests on the interplay of experimental observations with computational models. Key inputs, parameters, or structural aspects of models may be incomplete or unknown, and must be developed from indirect and limited observations. At the same time, quantified uncertainties are needed to qualify computational predictions in the support of design and decision-making. In this context, Bayesian statistics provides a foundation for inference from noisy and limited data, but at prohibitive computional expense. This project intends to make rigorous predictive modeling *feasible* in complex physical systems, via accelerated and scalable tools for uncertainty quantification, Bayesian inference, and experimental design. Specific objectives are as follows: 1. Develop adaptive posterior approximations and dimensionality reduction approaches for Bayesian inference in high-dimensional nonlinear systems. 2. Extend accelerated Bayesian methodologies to large-scale {\\em sequential} data assimilation, fully treating nonlinear models and non-Gaussian state and parameter distributions. 3. Devise efficient surrogate-based methods for Bayesian model selection and the learning of model structure. 4. Develop scalable simulation/optimization approaches to nonlinear Bayesian experimental design, for both parameter inference and model selection. 5. Demonstrate these inferential tools on chemical kinetic models in reacting flow, constructing and refining thermochemical and electrochemical models from limited data. Demonstrate Bayesian filtering on canonical stochastic PDEs and in the dynamic estimation of inhomogeneous subsurface properties and flow fields.
Design characteristics of safety parameter display system for nuclear power plants
International Nuclear Information System (INIS)
Zhang Yuangfang
1992-02-01
The design features of safety parameter display system (SPDS) developed by Tsinghua University is introduced. Some new features have been added into the system functions and they are: (1) hierarchical display structure; (2) human factor in the display format design; (3)automatic diagnosis of safety status of nuclear power plant; (4) extension of SPDS use scope; (5) flexible hardware structure. The new approaches in the design are: (1)adopting the international design standards; (2) selecting safety parameters strictly; (3) developing software under multitask operating system; (4) using a nuclear power plant simulator to verify the SPDS design
EXPERIMENTAL DETERMINATION OF DOUBLE VIBE FUNCTION PARAMETERS IN DIESEL ENGINES WITH BIODIESEL
Directory of Open Access Journals (Sweden)
Radivoje B Pešić
2010-01-01
Full Text Available A zero-dimensional, one zone model of engine cycle for steady-state regimes of engines and a simplified procedure for indicator diagrams analysis have been developed at the Laboratory for internal combustion engines, fuels and lubricants of the Faculty of Mechanical Engineering in Kragujevac. In addition to experimental research, thermodynamic modeling of working process of diesel engine with direct injection has been presented in this paper. The simplified procedure for indicator diagrams analysis has been applied, also. The basic problem, a selection of shape parameters of double Vibe function used for modeling the engine operation process, has been solved. The influence of biodiesel fuel and engine working regimes on the start of combustion, combustion duration and shape parameter of double Vibe was determined by a least square fit of experimental heat release curve.
International Nuclear Information System (INIS)
Cacuci, Dan Gabriel
2016-01-01
Highlights: • Predictive Modeling of Coupled Multi-Physics Systems (PM_CMPS) methodology is used. • Impact of measurements for reducing predicted uncertainties is highlighted. • Presented thermal-hydraulics benchmark illustrates generally applicable concepts. - Abstract: This work presents the application of the “Predictive Modeling of Coupled Multi-Physics Systems” (PM_CMPS) methodology conceived by Cacuci (2014) to a “test-section benchmark” problem in order to quantify the impact of measurements for reducing the uncertainties in the conceptual design of a proposed experimental facility aimed at investigating the thermal-hydraulics characteristics expected in the conceptual design of the G4M reactor (GEN4ENERGY, 2012). This “test-section benchmark” simulates the conditions experienced by the hottest rod within the conceptual design of the facility's test section, modeling the steady-state conduction in a rod heated internally by a cosinus-like heat source, as typically encountered in nuclear reactors, and cooled by forced convection to a surrounding coolant flowing along the rod. The PM_CMPS methodology constructs a prior distribution using all of the available computational and experimental information, by relying on the maximum entropy principle to maximize the impact of all available information and minimize the impact of ignorance. The PM_CMPS methodology then constructs the posterior distribution using Bayes’ theorem, and subsequently evaluates it via saddle-point methods to obtain explicit formulas for the predicted optimal temperature distributions and predicted optimal values for the thermal-hydraulics model parameters that characterized the test-section benchmark. In addition, the PM_CMPS methodology also yields reduced uncertainties for both the model parameters and responses. As a general rule, it is important to measure a quantity consistently with, and more accurately than, the information extant prior to the measurement. For
Neural Network Assisted Experimental Designs for Food Research
Directory of Open Access Journals (Sweden)
H.S. Ramaswamy
2000-06-01
Full Text Available The ability of artificial neural networks (ANN in predicting full factorial data from the fractional data corresponding to some of the commonly used experimental designs is explored in this paper. Factorial and fractional factorial designs such as L8, L9, L18, and Box and Behnken schemes were considered both in their original form and with some variations (L8+6, L15 and L9+1. Full factorial (3 factors x 5 levels and fractional data were generated employing sixteen different mathematical equations (four in each category: linear, with and without interactions, and non-linear, with and without interactions. Different ANN models were trained and the best model was chosen for each equation based on their ability to predict the fractional data. The best experimental design was then chosen based on their ability to simulate the full- factorial data for each equation. In several cases, the mean relative errors with the L18 design (which had more input data than other models were even higher than with other smaller fractional design. In general, the ANN assisted Lm, Box and Behnken, L15 and L18 designs were found to predict the full factorial data reasonably well with errors less than 5 %. The L8+6 model performed well with several experimental datasets reported in the literature.
Experimental designs for autoregressive models applied to industrial maintenance
International Nuclear Information System (INIS)
Amo-Salas, M.; López-Fidalgo, J.; Pedregal, D.J.
2015-01-01
Some time series applications require data which are either expensive or technically difficult to obtain. In such cases scheduling the points in time at which the information should be collected is of paramount importance in order to optimize the resources available. In this paper time series models are studied from a new perspective, consisting in the use of Optimal Experimental Design setup to obtain the best times to take measurements, with the principal aim of saving costs or discarding useless information. The model and the covariance function are expressed in an explicit form to apply the usual techniques of Optimal Experimental Design. Optimal designs for various approaches are computed and their efficiencies are compared. The methods working in an application of industrial maintenance of a critical piece of equipment at a petrochemical plant are shown. This simple model allows explicit calculations in order to show openly the procedure to find the correlation structure, needed for computing the optimal experimental design. In this sense the techniques used in this paper to compute optimal designs may be transferred to other situations following the ideas of the paper, but taking into account the increasing difficulty of the procedure for more complex models. - Highlights: • Optimal experimental design theory is applied to AR models to reduce costs. • The first observation has an important impact on any optimal design. • Either the lack of precision or small starting observations claim for large times. • Reasonable optimal times were obtained relaxing slightly the efficiency. • Optimal designs were computed in a predictive maintenance context
Design parameters for waste effluent treatment unit from beverages production
Mona A. Abdel-Fatah; H.O. Sherif; S.I. Hawash
2017-01-01
Based on a successful experimental result from laboratory and bench scale for treatment of wastewater from beverages industry, an industrial and efficient treatment unit is designed and constructed. The broad goal of this study was to design and construct effluent, cost effective and high quality treatment unit. The used technology is the activated sludge process of extended aeration type followed by rapid sand filters and chlorination as tertiary treatment. Experimental results have been con...
International Nuclear Information System (INIS)
Gu Weizu; Lu Jieju; Lu Mingjiang; Chen Tingyang
1988-01-01
A case study of spatial variability of Philip's infiltration parameters was carried out in a small experimental catchment with an area of 0.8 ha by nuclear monitoring methods. Relationships between sorptivity S, parameter A and the average initial soil water content within 0.5 m depth of soil profiles over the catchment have been plotted. A watershed infiltration parameter distribution curve is set up and fitted approximately by f/F=1-(1-S/S M ) n . The parameters of composite infiltration response related to whole catchment are suggested. The author has studied it on an experimental basin by combined method of nuclear technology and micro-geomorphic analysis. The results are satisfactory. (author). 6 refs, 11 figs, 2 tabs
Experimental design techniques in statistical practice a practical software-based approach
Gardiner, W P
1998-01-01
Provides an introduction to the diverse subject area of experimental design, with many practical and applicable exercises to help the reader understand, present and analyse the data. The pragmatic approach offers technical training for use of designs and teaches statistical and non-statistical skills in design and analysis of project studies throughout science and industry. Provides an introduction to the diverse subject area of experimental design and includes practical and applicable exercises to help understand, present and analyse the data Offers technical training for use of designs and teaches statistical and non-statistical skills in design and analysis of project studies throughout science and industry Discusses one-factor designs and blocking designs, factorial experimental designs, Taguchi methods and response surface methods, among other topics.
Statistical approach for uncertainty quantification of experimental modal model parameters
DEFF Research Database (Denmark)
Luczak, M.; Peeters, B.; Kahsin, M.
2014-01-01
Composite materials are widely used in manufacture of aerospace and wind energy structural components. These load carrying structures are subjected to dynamic time-varying loading conditions. Robust structural dynamics identification procedure impose tight constraints on the quality of modal models...... represent different complexity levels ranging from coupon, through sub-component up to fully assembled aerospace and wind energy structural components made of composite materials. The proposed method is demonstrated on two application cases of a small and large wind turbine blade........ This paper aims at a systematic approach for uncertainty quantification of the parameters of the modal models estimated from experimentally obtained data. Statistical analysis of modal parameters is implemented to derive an assessment of the entire modal model uncertainty measure. Investigated structures...
Parameters and design considerations for tomographic transmission scanners
International Nuclear Information System (INIS)
Pentlow, K.S.; Beattie, J.W.; Laughlin, J.S.
1976-01-01
The design of transverse axial transmission scanners for reconstruction tomography involves many interrelated parameters and conflicting requirements. We have investigated some of those parameters and their interactions and, where appropriate, attempted to optimize them. It is convenient to group the considerations under four headings: (1) Geometrical factors (basic configurations, rectilinear and fan geometry, moving detectors or static arrays, spatial response variations and field uniformity, and collimation); (2) Radiation energy and sources (Considerations here include transmission versus sensitivity, detector efficiency, collimator penetration, scattered radiation, patient dose, monochromatic versus polychromatic radiation and X-ray tubes versus radionuclide sources); (3) Detection systems (types of detector, detection modes and the rejection of scatter); and (4) Reconstruction mathematics and quantum noise. As a result of such considerations we have proposed a particular design which should have advantages in certain applications
Life on rock. Scaling down biological weathering in a new experimental design at Biosphere-2
Zaharescu, D. G.; Dontsova, K.; Burghelea, C. I.; Chorover, J.; Maier, R.; Perdrial, J. N.
2012-12-01
Biological colonization and weathering of bedrock on Earth is a major driver of landscape and ecosystem development, its effects reaching out into other major systems such climate and geochemical cycles of elements. In order to understand how microbe-plant-mycorrhizae communities interact with bedrock in the first phases of mineral weathering we developed a novel experimental design in the Desert Biome at Biosphere-2, University of Arizona (U.S.A). This presentation will focus on the development of the experimental setup. Briefly, six enclosed modules were designed to hold 288 experimental columns that will accommodate 4 rock types and 6 biological treatments. Each module is developed on 3 levels. A lower volume, able to withstand the weight of both, rock material and the rest of the structure, accommodates the sampling elements. A middle volume, houses the experimental columns in a dark chamber. A clear, upper section forms the habitat exposed to sunlight. This volume is completely sealed form exterior and it allows a complete control of its air and water parameters. All modules are connected in parallel with a double air purification system that delivers a permanent air flow. This setup is expected to provide a model experiment, able to test important processes in the interaction rock-life at grain-to- molecular scale.
Iurian, Sonia; Turdean, Luana; Tomuta, Ioan
2017-01-01
This study focuses on the development of a drug product based on a risk assessment-based approach, within the quality by design paradigm. A prolonged release system was proposed for paliperidone (Pal) delivery, containing Kollidon ® SR as an insoluble matrix agent and hydroxypropyl cellulose, hydroxypropyl methylcellulose (HPMC), or sodium carboxymethyl cellulose as a hydrophilic polymer. The experimental part was preceded by the identification of potential sources of variability through Ishikawa diagrams, and failure mode and effects analysis was used to deliver the critical process parameters that were further optimized by design of experiments. A D-optimal design was used to investigate the effects of Kollidon SR ratio ( X 1 ), the type of hydrophilic polymer ( X 2 ), and the percentage of hydrophilic polymer ( X 3 ) on the percentages of dissolved Pal over 24 h ( Y 1 - Y 9 ). Effects expressed as regression coefficients and response surfaces were generated, along with a design space for the preparation of a target formulation in an experimental area with low error risk. The optimal formulation contained 27.62% Kollidon SR and 8.73% HPMC and achieved the prolonged release of Pal, with low burst effect, at ratios that were very close to the ones predicted by the model. Thus, the parameters with the highest impact on the final product quality were studied, and safe ranges were established for their variations. Finally, a risk mitigation and control strategy was proposed to assure the quality of the system, by constant process monitoring.
Schweizer, Marin L.; Braun, Barbara I.; Milstone, Aaron M.
2016-01-01
Quasi-experimental studies evaluate the association between an intervention and an outcome using experiments in which the intervention is not randomly assigned. Quasi-experimental studies are often used to evaluate rapid responses to outbreaks or other patient safety problems requiring prompt non-randomized interventions. Quasi-experimental studies can be categorized into three major types: interrupted time series designs, designs with control groups, and designs without control groups. This methods paper highlights key considerations for quasi-experimental studies in healthcare epidemiology and antimicrobial stewardship including study design and analytic approaches to avoid selection bias and other common pitfalls of quasi-experimental studies. PMID:27267457
Design activities of a fusion experimental breeder
International Nuclear Information System (INIS)
Huang, J.; Feng, K.; Sheng, G.
1999-01-01
The fusion reactor design studies in China are under the support of a fusion-fission hybrid reactor research Program. The purpose of this program is to explore the potential near-term application of fusion energy to support the long-term fusion energy on the one hand and the fission energy development on the other. During 1992-1996 a detailed consistent and integral conceptual design of a Fusion Experimental Breeder, FEB was completed. Beginning from 1996, a further design study towards an Engineering Outline Design of the FEB, FEB-E, has started. The design activities are briefly given. (author)
Design activities of a fusion experimental breeder
International Nuclear Information System (INIS)
Huang, J.; Feng, K.; Sheng, G.
2001-01-01
The fusion reactor design studies in China are under the support of a fusion-fission hybrid reactor research Program. The purpose of this program is to explore the potential near-term application of fusion energy to support the long-term fusion energy on the one hand and the fission energy development on the other. During 1992-1996 a detailed consistent and integral conceptual design of a Fusion Experimental Breeder, FEB was completed. Beginning from 1996, a further design study towards an Engineering Outline Design of the FEB, FEB-E, has started. The design activities are briefly given. (author)
International Nuclear Information System (INIS)
Abdul Aziz Mohamed; Jaafar Abdullah; Dahlan Mohd; Rozaidi Rasid; Megat Harun AlRashid Megat Ahmad; Mahathir Mohamad; Mohd Hamzah Harun
2012-01-01
L 18 orthogonal array in mix level of Taguchi robust design method was carried out to optimize experimental conditions for the preparation of polymer blend composite. Tensile strength and neutron absorption of the composite were the properties of interest. Filler size, filler loading, ball mixing time and dispersion agent concentration were selected as parameters or factors which are expected to affect the composite properties. As a result of Taguchi analysis, filler loading was the most influencing parameter on the tensile strength and neutron absorption. The least influencing was ball-mixing time. The optimal conditions were determined by using mix-level Taguchi robust design method and a polymer composite with tensile strength of 6.33 MPa was successfully prepared. The composite was found to fully absorb thermal neutron flux of 1.04 x 10 5 n/ cm 2 / s with only 2 mm in thickness. In addition, the filler was also characterized by scanning electron microscopy (SEM) and elemental analysis (EDX). (Author)
An Introduction to Experimental Design Research
DEFF Research Database (Denmark)
Cash, Philip; Stanković, Tino; Štorga, Mario
2016-01-01
Design research brings together influences from the whole gamut of social, psychological, and more technical sciences to create a tradition of empirical study stretching back over 50 years (Horvath 2004; Cross 2007). A growing part of this empirical tradition is experimental, which has gained in ...
Uncertainty reevaluation of T/H parameters of HANARO core design
Energy Technology Data Exchange (ETDEWEB)
Kim, Hark Rho; Park, Cheol; Kim, Heo Nil; Chae, Hee Taek
1999-03-01
HANARO core was designed by statistical thermal design method which was generally applied to power plant design. However, reevaluation of core thermal margin reflecting design changes as well as experiences through commissioning and operation is necessary for safe operation of reactor. For this objective, the revision of data for T/H design parameters and the reevaluation of their uncertainties were performed. (Author). 30 refs., 7 figs.
Status of experimental data for the VHTR core design
Energy Technology Data Exchange (ETDEWEB)
Park, Won Seok; Chang, Jong Hwa; Park, Chang Kue
2004-05-01
The VHTR (Very High Temperature Reactor) is being emerged as a next generation nuclear reactor to demonstrate emission-free nuclear-assisted electricity and hydrogen production. The VHTR could be either a prismatic or pebble type helium cooled, graphite moderated reactor. The final decision will be made after the completion of the pre-conceptual design for each type. For the pre-conceptual design for both types, computational tools are being developed. Experimental data are required to validate the tools to be developed. Many experiments on the HTGR (High Temperature Gas-cooled Reactor) cores have been performed to confirm the design data and to validate the design tools. The applicability and availability of the existing experimental data have been investigated for the VHTR core design in this report.
Statistical experimental design for saltstone mixtures
International Nuclear Information System (INIS)
Harris, S.P.; Postles, R.L.
1991-01-01
We used a mixture experimental design for determining a window of operability for a process at the Savannah River Site Defense Waste Processing Facility (DWPF). The high-level radioactive waste at the Savannah River Site is stored in large underground carbon steel tanks. The waste consists of a supernate layer and a sludge layer. 137 Cs will be removed from the supernate by precipitation and filtration. After further processing, the supernate layer will be fixed as a grout for disposal in concrete vaults. The remaining precipitate will be processed at the DWPF with treated waste tank sludge and glass-making chemicals into borosilicate glass. The leach rate properties of the supernate grout, formed from various mixes of solidified salt waste, needed to be determined. The effective diffusion coefficients for NO 3 and Cr were used as a measure of leach rate. Various mixes of cement, Ca(OH) 2 , salt, slag and flyash were used. These constituents comprise the whole mix. Thus, a mixture experimental design was used
International Nuclear Information System (INIS)
Babenko, V. A.; Petrov, N. M.
2010-01-01
On the basis of the total cross sections for neutron-proton scattering in the region of laboratory energies below 150 keV, the value of σ 0 = 20.4288(146) b was obtained for the total cross sections for neutron-proton scattering at zero energy. This value is in very good agreement with the experimental cross sections obtained by Houke and Hurst, but it is at odds with Dilg's experimental cross section. By using the value that we found for σ 0 and the experimental values of the neutron-proton coherent scattering length f, the deuteron binding energy ε t , the deuteron effective radius ρ t (-ε t , -ε t ), and the total cross section in the region of energies below 5 MeV, the following values were found in the shape-parameter approximation for the low-energy parameters of neutron-proton scattering in the spin-triplet and spin-singlet states: a t = 5.4114(27) fm, r 0t = 1.7606(35) fm, v 2t = 0.157 fm 3 , a s = -23.7154(80) fm, r 0s = 2.706(67) fm, and v 2s = 0.491 fm 3 .
Experimental studies of parameters affecting the heat generation in friction stir welding process
Directory of Open Access Journals (Sweden)
Mijajlović Miroslav M.
2012-01-01
Full Text Available Heat generation is a complex process of transformation of a specific type of energy into heat. During friction stir welding, one part of mechanical energy delivered to the welding tool is consumed in the welding process, another is used for deformational processes etc., and the rest of the energy is transformed into heat. The analytical procedure for the estimation of heat generated during friction stir welding is very complex because it includes a significant number of variables and parameters, and many of them cannot be fully mathematically explained. Because of that, the analytical model for the estimation of heat generated during friction stir welding defines variables and parameters that dominantly affect heat generation. These parameters are numerous and some of them, e. g. loads, friction coefficient, torque, temperature, are estimated experimentally. Due to the complex geometry of the friction stir welding process and requirements of the measuring equipment, adequate measuring configurations and specific constructional solutions that provide adequate measuring positions are necessary. This paper gives an overview of the process of heat generation during friction stir welding, the most influencing parameters on heat generation, constructional solutions for the measuring equipment needed for these experimental researches and examples of measured values.
Energy Technology Data Exchange (ETDEWEB)
Guenette, C. C. [SINTEF Applied Cemistry, Trondheim (Norway)
1999-08-01
Design and site selection criteria for the Svalbard oil spill experiments are described. All three experimental sites have coarse and mixed sediment beaches of sand and pebble; within each site wave exposure is very similar; along-shore and across-shore sediment characteristics are also relatively homogeneous. Tidal range is in the order of 0.6 m at neaps, and 1.8 m at springs. All three sites are open to wave action and are ice-free during the experimental period of mid-July to mid-October. Study plots at each site were selected for different treatments from within the continuous stretch of oiled shoreline, with oiled buffer zones between plots and at either end of the oiled zone. Treatments included mixing (tilling), sediment relocation (surf washing) and bioremediation (nutrient enrichment). Measurements and observations were carried out during the summers of 1997 and 1998. The characteristics measured were: wave and wind conditions; beach topography and elevation; sediment grain size distribution; mineral fines size distribution and mineral composition; background hydrocarbons; concentration of oil within experimental plots and the rate of oil loss over time; depth of oil penetration and thickness of the oiled sediment layer; oil concentration and toxicity of near-shore benthic sediments; mineral composition of suspended particulate material captured in sub-tidal sediment traps; and oil-fines interaction in near-shore water samples. 1 fig.
Energy Technology Data Exchange (ETDEWEB)
Guenette, C. C. [SINTEF Applied Cemistry, Trondheim (Norway)
1999-07-01
Design and site selection criteria for the Svalbard oil spill experiments are described. All three experimental sites have coarse and mixed sediment beaches of sand and pebble; within each site waveexposure is very similar; along-shore and across-shore sediment characteristics are also relatively homogeneous. Tidal range is in the order of 0.6 m at neaps, and 1.8 m at springs. All three sites are open to wave action and are ice-free during the experimental period of mid-July to mid-October. Study plots at each site were selected for different treatments from within the continuous stretch of oiled shoreline, with oiled buffer zones between plots and at either end of the oiled zone. Treatments included mixing (tilling), sediment relocation (surf washing) and bioremediation (nutrient enrichment). Measurements and observations were carried out during the summers of 1997 and 1998. The characteristics measured were: wave and wind conditions; beach topography and elevation; sediment grain size distribution; mineral fines size distribution and mineral composition; background hydrocarbons; concentration of oil within experimental plots and the rate of oil loss over time; depth of oil penetration and thickness of the oiled sediment layer; oil concentration and toxicity of near-shore benthic sediments; mineral composition of suspended particulate material captured in sub-tidal sediment traps; and oil-fines interaction in near-shore water samples. 1 fig.
Zhang, Hang; Xu, Qingyan
2017-10-27
Grain selection is an important process in single crystal turbine blades manufacturing. Selector structure is a control factor of grain selection, as well as directional solidification (DS). In this study, the grain selection and structure design of the spiral selector were investigated through experimentation and simulation. A heat transfer model and a 3D microstructure growth model were established based on the Cellular automaton-Finite difference (CA-FD) method for the grain selector. Consequently, the temperature field, the microstructure and the grain orientation distribution were simulated and further verified. The average error of the temperature result was less than 1.5%. The grain selection mechanisms were further analyzed and validated through simulations. The structural design specifications of the selector were suggested based on the two grain selection effects. The structural parameters of the spiral selector, namely, the spiral tunnel diameter ( d w ), the spiral pitch ( h b ) and the spiral diameter ( h s ), were studied and the design criteria of these parameters were proposed. The experimental and simulation results demonstrated that the improved selector could accurately and efficiently produce a single crystal structure.
Oak Ridge Tokamak experimental power reactor study reference design
International Nuclear Information System (INIS)
Roberts, M.; Bettis, E.S.
1975-11-01
A Tokamak EPR Reference Design is presented as a basis for further design study leading to a Conceptual Design. The set of basic plasma parameters selected--minor radius of 2.25 m, major radius of 6.75 m, magnetic field on axis of 4.8 T and plasma current of 7.2 MA--should produce a reactor-grade plasma with a significant neutron flux, even with the great uncertainty in plasma physics scaling from present experience to large sizes. Neutronics and heat transfer calculations coupled with mechanical design and materials considerations were used to develop a blanket and shield capable of operating at high temperature, protecting the surrounding coils, being maintained remotely and, in a few experimental modules, breeding tritium. Nb 3 Sn and NbTi superconductors are used in the toroidal field coil design. The coil system was developed for a maximum field of 11 T at the winding (to give a field on axis of 4.8 T), and combines multifilamentary superconducting cable with forced flow of supercritical helium enclosed in a steel conduit. The structural system uses a stainless steel center bucking ring and intercoil box beam bracing to provide rigid support for coils against the centering force, overturning moments from poloidal fields and faults, other external forces, and thermal stresses. The poloidal magnetics system is specially designed both to reduce the total volt-second energy requirements and to reduce the magnitude of the rate of field change at the toroidal field coils. The rate of field change imposed upon the toroidal field coils is reduced by at least a factor of 3.3 compared to that due to the plasma alone. Tritium processing, tritium containment and vacuum systems employ double containment and atmospheric cleanup to minimize releases. The document also contains discussions of systems integration and assembly, key research and development needs, and schedule considerations
Discussion of the experimental methods of the estimation of the reaction impact parameter
International Nuclear Information System (INIS)
Muryn, B.; Dziunikowska, K.; Eskreys, A.; Coghen, T.
1978-01-01
Two methods of determination of the reaction impact parameter, the one proposed by Webber and other by Henyey and Pumplin, are compared and discussed. It is shown that the lower limits of the impact parameter bsub(L) obtained by means of these methods are comparable and are always very low (approximately < 0.5 fm). On the example of the Henyey - Pumplin method it is argued that the experimentally obtained values bsub(L) may be very unreliable estimates of the reaction impact parameter and that any comparison of different reactions or reactions channels may be meaningless. (author)
Nonlinear adaptive control system design with asymptotically stable parameter estimation error
Mishkov, Rumen; Darmonski, Stanislav
2018-01-01
The paper presents a new general method for nonlinear adaptive system design with asymptotic stability of the parameter estimation error. The advantages of the approach include asymptotic unknown parameter estimation without persistent excitation and capability to directly control the estimates transient response time. The method proposed modifies the basic parameter estimation dynamics designed via a known nonlinear adaptive control approach. The modification is based on the generalised prediction error, a priori constraints with a hierarchical parameter projection algorithm, and the stable data accumulation concepts. The data accumulation principle is the main tool for achieving asymptotic unknown parameter estimation. It relies on the parametric identifiability system property introduced. Necessary and sufficient conditions for exponential stability of the data accumulation dynamics are derived. The approach is applied in a nonlinear adaptive speed tracking vector control of a three-phase induction motor.
International Nuclear Information System (INIS)
Stillman, J.; Feldman, E.; Stevens, J.
2013-01-01
The design parameters for the conceptual design of a fuel assembly containing U-10Mo fuel foils with low-enriched uranium (LEU) for the University of Missouri Research Reactor (MURR) are described. The Design Demonstration Experiment (MURR-DDE) will use a prototypic MURR-LEU element manufactured according to the parameters specified here. Also provided are calculated performance parameters for the LEU element in the MURR, and a set of goals for the MURR-DDE related to those parameters. The conversion objectives are to develop a fuel element design that will ensure safe reactor operations, as well as maintaining existing performance. The element was designed by staff members of the Global Threat Reduction Initiative (GTRI) Reactor Conversion Program at the Argonne National Laboratory (ANL) and the MURR Facility. A set of manufacturing assumptions were provided by the Fuel Development (FD) and Fuel Fabrication Capability (FFC) pillars of the GTRI Reduced Enrichment for Research and Test Reactors (RERTR) program to reliably manufacture the fuel plates. The proposed LEU fuel element has an overall design and exterior dimensions that are similar to those of the current highly-enriched uranium (HEU) fuel elements. There are 23 fuel plates in the LEU design. The overall thickness of each plate is 44 mil, except for the exterior plate that is furthest from the center flux trap (plate 23), which is 49 mil thick. The proposed LEU fuel plates have U-10Mo monolithic fuel foils with a 235U enrichment of 19.75% varying from 9 mil to 20 mil thick, and clad with Al-6061 aluminum. A thin layer of zirconium exists between the fuel foils and the aluminum as a diffusion barrier. The thinnest nominal combined zirconium and aluminum clad thickness on each side of the fuel plates is 12 mil. The LEU U-10Mo monolithic fuel is not yet qualified as driver fuel in research reactors, but is under intense development under the auspices of the GTRI FD and FFC programs.
Experimental determination and verification of the parameters used in a proton pencil beam algorithm
International Nuclear Information System (INIS)
Szymanowski, H.; Mazal, A.; Nauraye, C.; Biensan, S.; Ferrand, R.; Murillo, M.C.; Caneva, S.; Gaboriaud, G.; Rosenwald, J.C.
2001-01-01
We present an experimental procedure for the determination and the verification under practical conditions of physical and computational parameters used in our proton pencil beam algorithm. The calculation of the dose delivered by a single pencil beam relies on a measured spread-out Bragg peak, and the description of its radial spread at depth features simple specific parameters accounting individually for the influence of the beam line as a whole, the beam energy modulation, the compensator, and the patient medium. For determining the experimental values of the physical parameters related to proton scattering, we utilized a simple relation between Gaussian radial spreads and the width of lateral penumbras. The contribution from the beam line has been extracted from lateral penumbra measurements in air: a linear variation with the distance collimator-point has been observed. Analytically predicted radial spreads within the patient were in good agreement with experimental values in water under various reference conditions. Results indicated no significant influence of the beam energy modulation. Using measurements in presence of Plexiglas slabs, a simple assumption on the effective source of scattering due to the compensator has been stated, leading to accurate radial spread calculations. Dose measurements in presence of complexly shaped compensators have been used to assess the performances of the algorithm supplied with the adequate physical parameters. One of these compensators has also been used, together with a reference configuration, for investigating a set of computational parameters decreasing the calculation time while maintaining a high level of accuracy. Faster dose computations have been performed for algorithm evaluation in the presence of geometrical and patient compensators, and have shown good agreement with the measured dose distributions
Parameters Design for Logarithmic Quantizer Based on Zoom Strategy
Directory of Open Access Journals (Sweden)
Jingjing Yan
2017-01-01
Full Text Available This paper is concerned with the problem of designing suitable parameters for logarithmic quantizer such that the closed-loop system is asymptotic convergent. Based on zoom strategy, we propose two methods for quantizer parameters design, under which it ensures that the state of the closed-loop system can load in the invariant sets after some certain moments. Then we obtain that the quantizer is unsaturated, and thus the quantization errors are bounded under the time-varying logarithm quantization strategy. On that basis, we obtain that the closed-loop system is asymptotic convergent. A benchmark example is given to show the usefulness of the proposed methods, and the comparison results are illustrated.
Directory of Open Access Journals (Sweden)
Cristian Rojas
2012-03-01
Full Text Available The aim of the present work was to optimize the sensorial and technological features of ice cream. The experimental work was performed in two stages: 1 optimization of lactose enzymatic hydrolysis, and 2 optimization of the process and product. For the first stage a complete factorial design was developed, optimized using both response surface and the steepest ascent method. In the second stage a mixture design was performed, combining the process variables. The product with the best sensorial acceptance, high yield and low cost was selected. The acceptance of the product was developed by an untrained taster’s panel. As a main result the sensorial and technological features of the final product were improved, establishing the optimum parameters for its elaboration.
System design overview of JAXA small supersonic experimental airplane (NEXST-1)
Takami, Hikaru; 高見 光
2007-01-01
The system of JAXA small supersonic experimental airplane (NEXST-1: National EXperimental Supersonic Transport-1) has been briefly explained. Some design problems that the designers have encountered have also been briefly explained.
Tire-road noise: an experimental study of tire and road design parameters
Bekke, Dirk; Wijnant, Ysbrand H.; Weegerink, Thijs; de Boer, Andries
2013-01-01
It is widely known that road traffic noise has negative influences on human health. Hence, as tire-road noise is considered to be the most dominant cause of road traffic noise above 30-50 km/h, a lot of research is performed by the two involving industries: road authorities/manufacturers and tire manufacturers. Usually, the parameters influencing exterior tire-road noise are often examined separately, whereas it is the tire-road interaction which obviously causes the actual noise. An integral...
Quasi-experimental study designs series-paper 7: assessing the assumptions.
Bärnighausen, Till; Oldenburg, Catherine; Tugwell, Peter; Bommer, Christian; Ebert, Cara; Barreto, Mauricio; Djimeu, Eric; Haber, Noah; Waddington, Hugh; Rockers, Peter; Sianesi, Barbara; Bor, Jacob; Fink, Günther; Valentine, Jeffrey; Tanner, Jeffrey; Stanley, Tom; Sierra, Eduardo; Tchetgen, Eric Tchetgen; Atun, Rifat; Vollmer, Sebastian
2017-09-01
Quasi-experimental designs are gaining popularity in epidemiology and health systems research-in particular for the evaluation of health care practice, programs, and policy-because they allow strong causal inferences without randomized controlled experiments. We describe the concepts underlying five important quasi-experimental designs: Instrumental Variables, Regression Discontinuity, Interrupted Time Series, Fixed Effects, and Difference-in-Differences designs. We illustrate each of the designs with an example from health research. We then describe the assumptions required for each of the designs to ensure valid causal inference and discuss the tests available to examine the assumptions. Copyright © 2017 Elsevier Inc. All rights reserved.
Design and verification of thermomechanical parameters of P/M Ti6Al4V alloy forging
Energy Technology Data Exchange (ETDEWEB)
Wojtaszek, Marek, E-mail: mwojtasz@metal.agh.edu.pl; Śleboda, Tomasz
2014-12-05
Highlights: • Thermomechanical parameters of P/M Ti6Al4V alloy processing were determined. • The use of the mixture of elemental powders allows reducing manufacturing costs. • Numerical modelling allowed to elaborate favourable parameters of forging. • The industrial trials of hot forging of P/M Ti6Al4V alloy were successful. - Abstract: This work is focused on the design of technology of forging high-quality Ti6Al4V alloy by means of powder metallurgy methods. A mixture of elemental powders, with the chemical composition of that of Ti6Al4V alloy, was used as a starting material for the investigation. Powder mixtures were fully densified by hot compaction under precisely controlled conditions. The mechanical properties of the obtained compacts were examined. The mechanical behaviour of the investigated alloy powder compacts was evaluated by compression test under various thermomechanical conditions using Gleeble simulator. The microstructure of powder compacts as well as P/M alloy samples deformed in compression tests was examined. All data obtained from the experimental tests were applied as boundary conditions for numerical simulation of forging of selected forgings. Basing on the results of both plastometric tests and simulations, thermomechanical parameters of the investigated alloy forging were determined. Designed parameters of forging technology were verified by forging trials performed in industrial conditions. The quality of the obtained forgings was examined by means of computed tomography.
Design and verification of thermomechanical parameters of P/M Ti6Al4V alloy forging
International Nuclear Information System (INIS)
Wojtaszek, Marek; Śleboda, Tomasz
2014-01-01
Highlights: • Thermomechanical parameters of P/M Ti6Al4V alloy processing were determined. • The use of the mixture of elemental powders allows reducing manufacturing costs. • Numerical modelling allowed to elaborate favourable parameters of forging. • The industrial trials of hot forging of P/M Ti6Al4V alloy were successful. - Abstract: This work is focused on the design of technology of forging high-quality Ti6Al4V alloy by means of powder metallurgy methods. A mixture of elemental powders, with the chemical composition of that of Ti6Al4V alloy, was used as a starting material for the investigation. Powder mixtures were fully densified by hot compaction under precisely controlled conditions. The mechanical properties of the obtained compacts were examined. The mechanical behaviour of the investigated alloy powder compacts was evaluated by compression test under various thermomechanical conditions using Gleeble simulator. The microstructure of powder compacts as well as P/M alloy samples deformed in compression tests was examined. All data obtained from the experimental tests were applied as boundary conditions for numerical simulation of forging of selected forgings. Basing on the results of both plastometric tests and simulations, thermomechanical parameters of the investigated alloy forging were determined. Designed parameters of forging technology were verified by forging trials performed in industrial conditions. The quality of the obtained forgings was examined by means of computed tomography
Inference of missing data and chemical model parameters using experimental statistics
Casey, Tiernan; Najm, Habib
2017-11-01
A method for determining the joint parameter density of Arrhenius rate expressions through the inference of missing experimental data is presented. This approach proposes noisy hypothetical data sets from target experiments and accepts those which agree with the reported statistics, in the form of nominal parameter values and their associated uncertainties. The data exploration procedure is formalized using Bayesian inference, employing maximum entropy and approximate Bayesian computation methods to arrive at a joint density on data and parameters. The method is demonstrated in the context of reactions in the H2-O2 system for predictive modeling of combustion systems of interest. Work supported by the US DOE BES CSGB. Sandia National Labs is a multimission lab managed and operated by Nat. Technology and Eng'g Solutions of Sandia, LLC., a wholly owned subsidiary of Honeywell Intl, for the US DOE NCSA under contract DE-NA-0003525.
Assessing robustness of designs for random effects parameters for nonlinear mixed-effects models.
Duffull, Stephen B; Hooker, Andrew C
2017-12-01
Optimal designs for nonlinear models are dependent on the choice of parameter values. Various methods have been proposed to provide designs that are robust to uncertainty in the prior choice of parameter values. These methods are generally based on estimating the expectation of the determinant (or a transformation of the determinant) of the information matrix over the prior distribution of the parameter values. For high dimensional models this can be computationally challenging. For nonlinear mixed-effects models the question arises as to the importance of accounting for uncertainty in the prior value of the variances of the random effects parameters. In this work we explore the influence of the variance of the random effects parameters on the optimal design. We find that the method for approximating the expectation and variance of the likelihood is of potential importance for considering the influence of random effects. The most common approximation to the likelihood, based on a first-order Taylor series approximation, yields designs that are relatively insensitive to the prior value of the variance of the random effects parameters and under these conditions it appears to be sufficient to consider uncertainty on the fixed-effects parameters only.
Optimal Experimental Design for Model Discrimination
Myung, Jay I.; Pitt, Mark A.
2009-01-01
Models of a psychological process can be difficult to discriminate experimentally because it is not easy to determine the values of the critical design variables (e.g., presentation schedule, stimulus structure) that will be most informative in differentiating them. Recent developments in sampling-based search methods in statistics make it…
International Nuclear Information System (INIS)
Borlandelli, E; Scarselli, D; Bettini, P; Morandini, M; Sala, G; Quadrio, M; Nespoli, A; Rigamonti, D; Villa, E
2015-01-01
Development and experimental testing of a peristaltic device actuated by a single shape-memory NiTi wire are described. The actuator is designed to radially shrink a compliant silicone pipe, and must work on a sustained basis at an actuation frequency that is higher than those typical of NiTi actuators. Four rigid, aluminum-made circular sectors are sitting along the pipe circumference and provide the required NiTi wire housing. The aluminum assembly acts as geometrical amplifier of the wire contraction and as heat sink required to dissipate the thermal energy of the wire during the cooling phase. We present and discuss the full experimental investigation of the actuator performance, measured in terms of its ability to reduce the pipe diameter, at a sustained frequency of 1.5 Hz. Moreover, we investigate how the diameter contraction is affected by various design parameters as well as actuation frequencies up to 4 Hz. We manage to make the NiTi wire work at 3% in strain, cyclically providing the designed pipe wall displacement. The actuator performance is found to decay approximately linearly with actuation frequencies up to 4 Hz. Also, the interface between the wire and the aluminum parts is found to be essential in defining the functional performance of the actuator. (paper)
Nonlinearity Analysis and Parameters Optimization for an Inductive Angle Sensor
Directory of Open Access Journals (Sweden)
Lin Ye
2014-02-01
Full Text Available Using the finite element method (FEM and particle swarm optimization (PSO, a nonlinearity analysis based on parameter optimization is proposed to design an inductive angle sensor. Due to the structure complexity of the sensor, understanding the influences of structure parameters on the nonlinearity errors is a critical step in designing an effective sensor. Key parameters are selected for the design based on the parameters’ effects on the nonlinearity errors. The finite element method and particle swarm optimization are combined for the sensor design to get the minimal nonlinearity error. In the simulation, the nonlinearity error of the optimized sensor is 0.053% in the angle range from −60° to 60°. A prototype sensor is manufactured and measured experimentally, and the experimental nonlinearity error is 0.081% in the angle range from −60° to 60°.
Energy Technology Data Exchange (ETDEWEB)
Casoli, P.; Authier, N.; Baud, J. [Commissariat a l' energie Atomique, Centre de Valduc, 21120 Is-sur-Tille (France)
2009-07-01
Several experimental devices are operated by the Criticality and Neutron Science Research Department of the CEA Valduc Laboratory. One of these is the metallic core reactor Caliban. The knowledge of the fundamental kinetic parameters of the reactor is very useful, indeed necessary, to the operator. The purpose of this study was to develop and perform experiments allowing to determinate some of these parameters. The prompt neutron decay constant and particularly its value at criticality can be measured with reactor noise techniques such as the interval-distribution, the Feynman variance-to-mean, and the Rossi-{alpha} methods. By introducing the Nelson number, the effective delayed neutron fraction and the average neutron lifetime can also be calculated with the Rossi-{alpha} method. Subcritical, critical, and even supercritical experiments were performed. With the Rossi-{alpha} technique, it was found that the prompt neutron decay constant at criticality was (6.02*10{sup 5} {+-} 9%). Experiments also brought out the limitations of the used experimental parameters. (authors)
Wang, Y; Harrison, M; Clark, B J
2006-02-10
An optimization strategy for the separation of an acidic mixture by employing a monolithic stationary phase is presented, with the aid of experimental design and response surface methodology (RSM). An orthogonal array design (OAD) OA(16) (2(15)) was used to choose the significant parameters for the optimization. The significant factors were optimized by using a central composite design (CCD) and the quadratic models between the dependent and the independent parameters were built. The mathematical models were tested on a number of simulated data set and had a coefficient of R(2) > 0.97 (n = 16). On applying the optimization strategy, the factor effects were visualized as three-dimensional (3D) response surfaces and contour plots. The optimal condition was achieved in less than 40 min by using the monolithic packing with the mobile phase of methanol/20 mM phosphate buffer pH 2.7 (25.5/74.5, v/v). The method showed good agreement between the experimental data and predictive value throughout the studied parameter space and were suitable for optimization studies on the monolithic stationary phase for acidic compounds.
Design and experimentation of BSFQ logic devices
International Nuclear Information System (INIS)
Hosoki, T.; Kodaka, H.; Kitagawa, M.; Okabe, Y.
1999-01-01
Rapid single flux quantum (RSFQ) logic needs synchronous pulses for each gate, so the clock-wiring problem is more serious when designing larger scale circuits with this logic. So we have proposed a new SFQ logic which follows Boolean algebra perfectly by using set and reset pulses. With this logic, the level information of current input is transmitted with these pulses generated by level-to-pulse converters, and each gate calculates logic using its phase level made by these pulses. Therefore, our logic needs no clock in each gate. We called this logic 'Boolean SFQ (BSFQ) logic'. In this paper, we report design and experimentation for an AND gate with inverting input based on BSFQ logic. The experimental results for OR and XOR gates are also reported. (author)
Using IMPRINT to Guide Experimental Design with Simulated Task Environments
2015-06-18
USING IMPRINT TO GUIDE EXPERIMENTAL DESIGN OF SIMULATED TASK ENVIRONMENTS THESIS Gregory...ENG-MS-15-J-052 USING IMPRINT TO GUIDE EXPERIMENTAL DESIGN WITH SIMULATED TASK ENVIRONMENTS THESIS Presented to the Faculty Department...Civilian, USAF June 2015 DISTRIBUTION STATEMENT A. APPROVED FOR PUBLIC RELEASE; DISTRIBUTION UNLIMITED. AFIT-ENG-MS-15-J-052 USING IMPRINT
A System for Extracting Study Design Parameters from Nutritional Genomics Abstracts
Directory of Open Access Journals (Sweden)
Kelly Cassidy
2013-06-01
Full Text Available The extraction of study design parameters from biomedical journal articles is an important problem in natural language processing (NLP. Such parameters define the characteristics of a study, such as the duration, the number of subjects, and their profile. Here we present a system for extracting study design parameters from sentences in article abstracts. This system will be used as a component of a larger system for creating nutrigenomics networks from articles in the nutritional genomics domain. The algorithms presented consist of manually designed rules expressed either as regular expressions or in terms of sentence parse structure. A number of filters and NLP tools are also utilized within a pipelined algorithmic framework. Using this novel approach, our system performs extraction at a finer level of granularity than comparable systems, while generating results that surpass the current state of the art.
Wang, Xuntao; Feng, Jianhu; Wang, Hu; Hong, Shidi; Zheng, Supei
2018-03-01
A three-dimensional finite element box girder bridge and its asphalt concrete deck pavement were established by ANSYS software, and the interlayer bonding condition of asphalt concrete deck pavement was assumed to be contact bonding condition. Orthogonal experimental design is used to arrange the testing plans of material parameters, and an evaluation of the effect of different material parameters in the mechanical response of asphalt concrete surface layer was conducted by multiple linear regression model and using the results from the finite element analysis. Results indicated that stress regression equations can well predict the stress of the asphalt concrete surface layer, and elastic modulus of waterproof layer has a significant influence on stress values of asphalt concrete surface layer.
Bisetti, Fabrizio
2016-01-12
The analysis of reactive systems in combustion science and technology relies on detailed models comprising many chemical reactions that describe the conversion of fuel and oxidizer into products and the formation of pollutants. Shock-tube experiments are a convenient setting for measuring the rate parameters of individual reactions. The temperature, pressure, and concentration of reactants are chosen to maximize the sensitivity of the measured quantities to the rate parameter of the target reaction. In this study, we optimize the experimental setup computationally by optimal experimental design (OED) in a Bayesian framework. We approximate the posterior probability density functions (pdf) using truncated Gaussian distributions in order to account for the bounded domain of the uniform prior pdf of the parameters. The underlying Gaussian distribution is obtained in the spirit of the Laplace method, more precisely, the mode is chosen as the maximum a posteriori (MAP) estimate, and the covariance is chosen as the negative inverse of the Hessian of the misfit function at the MAP estimate. The model related entities are obtained from a polynomial surrogate. The optimality, quantified by the information gain measures, can be estimated efficiently by a rejection sampling algorithm against the underlying Gaussian probability distribution, rather than against the true posterior. This approach offers a significant error reduction when the magnitude of the invariants of the posterior covariance are comparable to the size of the bounded domain of the prior. We demonstrate the accuracy and superior computational efficiency of our method for shock-tube experiments aiming to measure the model parameters of a key reaction which is part of the complex kinetic network describing the hydrocarbon oxidation. In the experiments, the initial temperature and fuel concentration are optimized with respect to the expected information gain in the estimation of the parameters of the target
WIPP Compliance Certification Application calculations parameters. Part 1: Parameter development
International Nuclear Information System (INIS)
Howarth, S.M.
1997-01-01
The Waste Isolation Pilot Plant (WIPP) in southeast New Mexico has been studied as a transuranic waste repository for the past 23 years. During this time, an extensive site characterization, design, construction, and experimental program was completed, which provided in-depth understanding of the dominant processes that are most likely to influence the containment of radionuclides for 10,000 years. Nearly 1,500 parameters were developed using information gathered from this program; the parameters were input to numerical models for WIPP Compliance Certification Application (CCA) Performance Assessment (PA) calculations. The CCA probabilistic codes frequently require input values that define a statistical distribution for each parameter. Developing parameter distributions begins with the assignment of an appropriate distribution type, which is dependent on the type, magnitude, and volume of data or information available. The development of the parameter distribution values may require interpretation or statistical analysis of raw data, combining raw data with literature values, scaling of lab or field data to fit code grid mesh sizes, or other transformation. Parameter development and documentation of the development process were very complicated, especially for those parameters based on empirical data; they required the integration of information from Sandia National Laboratories (SNL) code sponsors, parameter task leaders (PTLs), performance assessment analysts (PAAs), and experimental principal investigators (PIs). This paper, Part 1 of two parts, contains a discussion of the parameter development process, roles and responsibilities, and lessons learned. Part 2 will discuss parameter documentation, traceability and retrievability, and lessons learned from related audits and reviews
Design parameters and source terms: Volume 2, Source terms: Revision 0
International Nuclear Information System (INIS)
1987-10-01
The Design Parameters and Source Terms Document was prepared in accordance with DOE request and to provide data for the environmental impact study to be performed in the future for the Deaf Smith County, Texas site for a nuclear waste repository in salt. This document updates a previous unpublished report by Stearns Catalytic Corporation (SCC), entitled ''Design Parameters and Source Terms for a Two-Phase Repository Salt,'' 1985, to the level of the Site Characterization Plan - Conceptual Design Report. The previous unpublished SCC Study identifies the data needs for the Environmental Assessment effort for seven possible Salt Repository sites. 2 tabs
Optimizing an experimental design for an electromagnetic experiment
Roux, Estelle; Garcia, Xavier
2013-04-01
Most of geophysical studies focus on data acquisition and analysis, but another aspect which is gaining importance is the discussion on acquisition of suitable datasets. This can be done through the design of an optimal experiment. Optimizing an experimental design implies a compromise between maximizing the information we get about the target and reducing the cost of the experiment, considering a wide range of constraints (logistical, financial, experimental …). We are currently developing a method to design an optimal controlled-source electromagnetic (CSEM) experiment to detect a potential CO2 reservoir and monitor this reservoir during and after CO2 injection. Our statistical algorithm combines the use of linearized inverse theory (to evaluate the quality of one given design via the objective function) and stochastic optimization methods like genetic algorithm (to examine a wide range of possible surveys). The particularity of our method is that it uses a multi-objective genetic algorithm that searches for designs that fit several objective functions simultaneously. One main advantage of this kind of technique to design an experiment is that it does not require the acquisition of any data and can thus be easily conducted before any geophysical survey. Our new experimental design algorithm has been tested with a realistic one-dimensional resistivity model of the Earth in the region of study (northern Spain CO2 sequestration test site). We show that a small number of well distributed observations have the potential to resolve the target. This simple test also points out the importance of a well chosen objective function. Finally, in the context of CO2 sequestration that motivates this study, we might be interested in maximizing the information we get about the reservoir layer. In that case, we show how the combination of two different objective functions considerably improve its resolution.
Adachi, Satoshi; Takayanagi, Masahiro; 足立 聡; 高柳 昌弘
2007-01-01
Dependency of interparticle distance in Coulomb crystal on various parameters such as plasma density, electron temperature, plasma potential and the Debye length are experimentally investigated. From the investigation, it is found that the interparticle distance is proportional to the Debye length.
Design and Experimental Study on Spinning Solid Rocket Motor
Xue, Heng; Jiang, Chunlan; Wang, Zaicheng
The study on spinning solid rocket motor (SRM) which used as power plant of twice throwing structure of aerial submunition was introduced. This kind of SRM which with the structure of tangential multi-nozzle consists of a combustion chamber, propellant charge, 4 tangential nozzles, ignition device, etc. Grain design, structure design and prediction of interior ballistic performance were described, and problem which need mainly considered in design were analyzed comprehensively. Finally, in order to research working performance of the SRM, measure pressure-time curve and its speed, static test and dynamic test were conducted respectively. And then calculated values and experimental data were compared and analyzed. The results indicate that the designed motor operates normally, and the stable performance of interior ballistic meet demands. And experimental results have the guidance meaning for the pre-research design of SRM.
Autonomous entropy-based intelligent experimental design
Malakar, Nabin Kumar
2011-07-01
The aim of this thesis is to explore the application of probability and information theory in experimental design, and to do so in a way that combines what we know about inference and inquiry in a comprehensive and consistent manner. Present day scientific frontiers involve data collection at an ever-increasing rate. This requires that we find a way to collect the most relevant data in an automated fashion. By following the logic of the scientific method, we couple an inference engine with an inquiry engine to automate the iterative process of scientific learning. The inference engine involves Bayesian machine learning techniques to estimate model parameters based upon both prior information and previously collected data, while the inquiry engine implements data-driven exploration. By choosing an experiment whose distribution of expected results has the maximum entropy, the inquiry engine selects the experiment that maximizes the expected information gain. The coupled inference and inquiry engines constitute an autonomous learning method for scientific exploration. We apply it to a robotic arm to demonstrate the efficacy of the method. Optimizing inquiry involves searching for an experiment that promises, on average, to be maximally informative. If the set of potential experiments is described by many parameters, the search involves a high-dimensional entropy space. In such cases, a brute force search method will be slow and computationally expensive. We develop an entropy-based search algorithm, called nested entropy sampling, to select the most informative experiment. This helps to reduce the number of computations necessary to find the optimal experiment. We also extended the method of maximizing entropy, and developed a method of maximizing joint entropy so that it could be used as a principle of collaboration between two robots. This is a major achievement of this thesis, as it allows the information-based collaboration between two robotic units towards a same
Design and experimental verification for optical module of optical vector-matrix multiplier.
Zhu, Weiwei; Zhang, Lei; Lu, Yangyang; Zhou, Ping; Yang, Lin
2013-06-20
Optical computing is a new method to implement signal processing functions. The multiplication between a vector and a matrix is an important arithmetic algorithm in the signal processing domain. The optical vector-matrix multiplier (OVMM) is an optoelectronic system to carry out this operation, which consists of an electronic module and an optical module. In this paper, we propose an optical module for OVMM. To eliminate the cross talk and make full use of the optical elements, an elaborately designed structure that involves spherical lenses and cylindrical lenses is utilized in this optical system. The optical design software package ZEMAX is used to optimize the parameters and simulate the whole system. Finally, experimental data is obtained through experiments to evaluate the overall performance of the system. The results of both simulation and experiment indicate that the system constructed can implement the multiplication between a matrix with dimensions of 16 by 16 and a vector with a dimension of 16 successfully.
Calì, M.; Santarelli, M. G. L.; Leone, P.
Gas Turbine Technologies (GTT) and Politecnico di Torino, both located in Torino (Italy), have been involved in the design and installation of a SOFC laboratory in order to analyse the operation, in cogenerative configuration, of the CHP 100 kW e SOFC Field Unit, built by Siemens-Westinghouse Power Corporation (SWPC), which is at present (May 2005) starting its operation and which will supply electric and thermal power to the GTT factory. In order to take the better advantage from the analysis of the on-site operation, and especially to correctly design the scheduled experimental tests on the system, we developed a mathematical model and run a simulated experimental campaign, applying a rigorous statistical approach to the analysis of the results. The aim of this work is the computer experimental analysis, through a statistical methodology (2 k factorial experiments), of the CHP 100 performance. First, the mathematical model has been calibrated with the results acquired during the first CHP100 demonstration at EDB/ELSAM in Westerwoort. After, the simulated tests have been performed in the form of computer experimental session, and the measurement uncertainties have been simulated with perturbation imposed to the model independent variables. The statistical methodology used for the computer experimental analysis is the factorial design (Yates' Technique): using the ANOVA technique the effect of the main independent variables (air utilization factor U ox, fuel utilization factor U F, internal fuel and air preheating and anodic recycling flow rate) has been investigated in a rigorous manner. Analysis accounts for the effects of parameters on stack electric power, thermal recovered power, single cell voltage, cell operative temperature, consumed fuel flow and steam to carbon ratio. Each main effect and interaction effect of parameters is shown with particular attention on generated electric power and stack heat recovered.
Sathiya, P.; Panneerselvam, K.; Soundararajan, R.
2012-09-01
Laser welding input parameters play a very significant role in determining the quality of a weld joint. The joint quality can be defined in terms of properties such as weld bead geometry, mechanical properties and distortion. Therefore, mechanical properties should be controlled to obtain good welded joints. In this study, the weld bead geometry such as depth of penetration (DP), bead width (BW) and tensile strength (TS) of the laser welded butt joints made of AISI 904L super austenitic stainless steel were investigated. Full factorial design was used to carry out the experimental design. Artificial Neural networks (ANN) program was developed in MatLab software to establish the relationships between the laser welding input parameters like beam power, travel speed and focal position and the three responses DP, BW and TS in three different shielding gases (Argon, Helium and Nitrogen). The established models were used for optimizing the process parameters using Genetic Algorithm (GA). Optimum solutions for the three different gases and their respective responses were obtained. Confirmation experiment has also been conducted to validate the optimized parameters obtained from GA.
Scaling laws of design parameters for plasma wakefield accelerators
International Nuclear Information System (INIS)
Uhm, Han S.; Nam, In H.; Suk, Hyyong
2012-01-01
Simple scaling laws for the design parameters of plasma wakefield accelerators were obtained using a theoretical model, which were confirmed via particle simulation studies. It was found that the acceleration length was given by Δx=0.804λ p /(1−β g ), where λ p is the plasma wavelength and β g c the propagation velocity of the ion cavity. The acceleration energy can also be given by ΔE=(γ m −1)mc 2 =2.645mc 2 /(1−β g ), where m is the electron rest mass. As expected, the acceleration length and energy increase drastically as β g approached unity. These simple scaling laws can be very instrumental in the design of better-performing plasma wakefield accelerators. -- Highlights: ► Simple scaling laws for the design parameters of laser wakefield accelerators were obtained using a theoretical model. ► The scaling laws for acceleration length and acceleration energy were compared with particle-in-cell simulation results. ► The acceleration length and the energy increase drastically as β g approaches unity. ► These simple scaling laws can be very instrumental in the design of laser wakefield accelerators.
Physics design and experimental study of tokamak divertor
International Nuclear Information System (INIS)
Yan Jiancheng; Gao Qingdi; Yan Longwen; Wang Mingxu; Deng Baiquan; Zhang Fu; Zhang Nianman; Ran Hong; Cheng Fayin; Tang Yiwu; Chen Xiaoping
2007-06-01
The divertor configuration of HL-2A tokamak is optimized, and the plasma performance in divertor is simulated with B2-code. The effects of collisionality on plasma-wall transition in the scrape-off layer of divertor are investigated, high performances of the divertor plasma in HL-2A are simulated, and a quasi- stationary RS operation mode is established with the plasma controlled by LHCD and NBI. HL-2A tokamak has been successfully operated in divertor configuration. The major parameters: plasma current I p =320 kA, toroidal field B t =2.2 T, plasma discharger duration T d =1580 ms ware achieved at the end of 2004. The preliminary experimental researches of advanced diverter have been carried out. Design studies of divertor target plate for high power density fusion reactor have been carried out, especially, the physical processes on the surface of flowing liquid lithium target plate. The exploration research of improving divertor ash removal efficiency and reducing tritium inventory resulting from applying the RF ponderomotive force potential is studied. The optimization structure design studies of FEB-E reactor divertor are performed. High flux thermal shock experiments were carried on tungsten and carbon based materials. Hot Isostatic Press (HIP) method was employed to bond tungsten to copper alloys. Electron beam simulated thermal fatigue tests were also carried out to W/Cu bondings. Thermal desorption and surface modification of He + implanted into tungsten have been studied. (authors)
Design parameters for voltage-controllable directed assembly of single nanoparticles
International Nuclear Information System (INIS)
Porter, Benjamin F; Bhaskaran, Harish; Abelmann, Leon
2013-01-01
Techniques to reliably pick-and-place single nanoparticles into functional assemblies are required to incorporate exotic nanoparticles into standard electronic circuits. In this paper we explore the use of electric fields to drive and direct the assembly process, which has the advantage of being able to control the nano-assembly process at the single nanoparticle level. To achieve this, we design an electrostatic gating system, thus enabling a voltage-controllable nanoparticle picking technique. Simulating this system with the nonlinear Poisson–Boltzmann equation, we can successfully characterize the parameters required for single particle placement, the key being single particle selectivity, in effect designing a system that can achieve this controllably. We then present the optimum design parameters required for successful single nanoparticle placement at ambient temperature, an important requirement for nanomanufacturing processes. (paper)
Electron-optical design parameters for a high-resolution electron monochromator
International Nuclear Information System (INIS)
Tanaka, H.; Huebner, R.H.
1976-01-01
Detailed design parameters of a new, high-resolution electron monochromator are presented. The design utilizes a hemispherical filter as the energy-dispersing element and combines both cylindrical and aperture electrostatic lenses to accelerate, decelerate, transport, and focus the electron beam from the cathode to the interaction region
Design parameters for waste effluent treatment unit from beverages production
Directory of Open Access Journals (Sweden)
Mona A. Abdel-Fatah
2017-09-01
Full Text Available Based on a successful experimental result from laboratory and bench scale for treatment of wastewater from beverages industry, an industrial and efficient treatment unit is designed and constructed. The broad goal of this study was to design and construct effluent, cost effective and high quality treatment unit. The used technology is the activated sludge process of extended aeration type followed by rapid sand filters and chlorination as tertiary treatment. Experimental results have been considered as the basis for full scale design of the industrial capacity of 1600 m3/day treatment plant. Final effluent characteristics after treatment comply with Egyptian legalizations after reducing COD and BOD5 by about 97% and 95% respectively. So it is recommended to reuse treated effluent in textile industry in dyeing process.
Optimization Design of Multi-Parameters in Rail Launcher System
Yujiao Zhang; Weinan Qin; Junpeng Liao; Jiangjun Ruan
2014-01-01
Today the energy storage systems are still encumbering, therefore it is useful to think about the optimization of a railgun system in order to achieve the best performance with the lowest energy input. In this paper, an optimal design method considering 5 parameters is proposed to improve the energy conversion efficiency of a simple railgun. In order to avoid costly trials, the field- circuit method is employed to analyze the operations of different structural railguns with different paramete...
Priority design parameters of industrialized optical fiber sensors in civil engineering
Wang, Huaping; Jiang, Lizhong; Xiang, Ping
2018-03-01
Considering the mechanical effects and the different paths for transferring deformation, optical fiber sensors commonly used in civil engineering have been systematically classified. Based on the strain transfer theory, the relationship between the strain transfer coefficient and allowable testing error is established. The proposed relationship is regarded as the optimal control equation to obtain the optimal value of sensors that satisfy the requirement of measurement precision. Furthermore, specific optimization design methods and priority design parameters of the classified sensors are presented. This research indicates that (1) strain transfer theory-based optimization design method is much suitable for the sensor that depends on the interfacial shear stress to transfer the deformation; (2) the priority design parameters are bonded (sensing) length, interfacial bonded strength, elastic modulus and radius of protective layer and thickness of adhesive layer; (3) the optimization design of sensors with two anchor pieces at two ends is independent of strain transfer theory as the strain transfer coefficient can be conveniently calibrated by test, and this kind of sensors has no obvious priority design parameters. Improved calibration test is put forward to enhance the accuracy of the calibration coefficient of end-expanding sensors. By considering the practical state of sensors and the testing accuracy, comprehensive and systematic analyses on optical fiber sensors are provided from the perspective of mechanical actions, which could scientifically instruct the application design and calibration test of industrialized optical fiber sensors.
Sellami, Takwa; Jelassi, Sana; Darcherif, Abdel Moumen; Berriri, Hanen; Mimouni, Med Faouzi
2018-04-01
With the advancement of wind turbines towards complex structures, the requirement of trusty structural models has become more apparent. Hence, the vibration characteristics of the wind turbine components, like the blades and the tower, have to be extracted under vibration constraints. Although extracting the modal properties of blades is a simple task, calculating precise modal data for the whole wind turbine coupled to its tower/foundation is still a perplexing task. In this framework, this paper focuses on the investigation of the structural modeling approach of modern commercial micro-turbines. Thus, the structural model a complex designed wind turbine, which is Rutland 504, is established based on both experimental and numerical methods. A three-dimensional (3-D) numerical model of the structure was set up based on the finite volume method (FVM) using the academic finite element analysis software ANSYS. To validate the created model, experimental vibration tests were carried out using the vibration test system of TREVISE platform at ECAM-EPMI. The tests were based on the experimental modal analysis (EMA) technique, which is one of the most efficient techniques for identifying structures parameters. Indeed, the poles and residues of the frequency response functions (FRF), between input and output spectra, were calculated to extract the mode shapes and the natural frequencies of the structure. Based on the obtained modal parameters, the numerical designed model was up-dated.
Automated scheme to determine design parameters for a recoverable reentry vehicle
International Nuclear Information System (INIS)
Williamson, W.E.
1976-01-01
The NRV (Nosetip Recovery Vehicle) program at Sandia Laboratories is designed to recover the nose section from a sphere cone reentry vehicle after it has flown a near ICBM reentry trajectory. Both mass jettison and parachutes are used to reduce the velocity of the RV near the end of the trajectory to a sufficiently low level that the vehicle may land intact. The design problem of determining mass jettison time and parachute deployment time in order to ensure that the vehicle does land intact is considered. The problem is formulated as a min-max optimization problem where the design parameters are to be selected to minimize the maximum possible deviation in the design criteria due to uncertainties in the system. The results of the study indicate that the optimal choice of the design parameters ensures that the maximum deviation in the design criteria is within acceptable bounds. This analytically ensures the feasibility of recovery for NRV
Design of Safety Parameter Monitoring Function in a Research Reactor Facility
Energy Technology Data Exchange (ETDEWEB)
Park, Jaekwan; Suh, Yongsuk [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)
2014-05-15
The primary purpose of the safety parameter monitoring system (SPDS) is to help operating personnel in the control room make quick assessments of the plant safety status. Thus, the basic function of the SPDS is a provision of a continuous indication of plant parameters or derived variables representative of the safety status of the plant. NUREG-0737 Supplement 1 provides details of the functional criteria for the SPDS, as one of the action plan requirements from TMI accident. The system provides various functions as follows: · Alerting based on safety function decision logics, · Success path analysis to achieve the integrity of the safety functions, · 3 layer display architecture - safety function, success path display for each safety function, system summary and equipment details for each safety function, · Integration with computer-based procedure. According to a Notice of the NSSC No. 2012-31, a research reactor facility generating more than 2 MW of power should also be furnished with the SPDS for emergency preparedness. Generally, a research reactor is a small size facility, and its number of instrumentations is fewer than that of NPPs. In particular, it is actually hard to have various and powerful functions from an economic perspective. Therefore, a safety parameter display system optimized for a research reactor facility must be proposed. This paper provides the requirement analysis results and proposes the design of safety parameter monitoring function for a research reactor. The safety parameter monitoring function supporting control room personnel during emergency conditions should be designed in a research reactor facility. The facility size and number of signals are smaller than that of the power plants. Also, it is actually hard to have various and powerful functions of nuclear power plants from an economic perspective. Thus, a safety parameter display system optimized to a research reactor must be proposed. First, we found important design items
Design of Safety Parameter Monitoring Function in a Research Reactor Facility
International Nuclear Information System (INIS)
Park, Jaekwan; Suh, Yongsuk
2014-01-01
The primary purpose of the safety parameter monitoring system (SPDS) is to help operating personnel in the control room make quick assessments of the plant safety status. Thus, the basic function of the SPDS is a provision of a continuous indication of plant parameters or derived variables representative of the safety status of the plant. NUREG-0737 Supplement 1 provides details of the functional criteria for the SPDS, as one of the action plan requirements from TMI accident. The system provides various functions as follows: · Alerting based on safety function decision logics, · Success path analysis to achieve the integrity of the safety functions, · 3 layer display architecture - safety function, success path display for each safety function, system summary and equipment details for each safety function, · Integration with computer-based procedure. According to a Notice of the NSSC No. 2012-31, a research reactor facility generating more than 2 MW of power should also be furnished with the SPDS for emergency preparedness. Generally, a research reactor is a small size facility, and its number of instrumentations is fewer than that of NPPs. In particular, it is actually hard to have various and powerful functions from an economic perspective. Therefore, a safety parameter display system optimized for a research reactor facility must be proposed. This paper provides the requirement analysis results and proposes the design of safety parameter monitoring function for a research reactor. The safety parameter monitoring function supporting control room personnel during emergency conditions should be designed in a research reactor facility. The facility size and number of signals are smaller than that of the power plants. Also, it is actually hard to have various and powerful functions of nuclear power plants from an economic perspective. Thus, a safety parameter display system optimized to a research reactor must be proposed. First, we found important design items
Bashyam, Ashvin; Li, Matthew; Cima, Michael J
2018-07-01
Single-sided NMR has the potential for broad utility and has found applications in healthcare, materials analysis, food quality assurance, and the oil and gas industry. These sensors require a remote, strong, uniform magnetic field to perform high sensitivity measurements. We demonstrate a new permanent magnet geometry, the Unilateral Linear Halbach, that combines design principles from "sweet-spot" and linear Halbach magnets to achieve this goal through more efficient use of magnetic flux. We perform sensitivity analysis using numerical simulations to produce a framework for Unilateral Linear Halbach design and assess tradeoffs between design parameters. Additionally, the use of hundreds of small, discrete magnets within the assembly allows for a tunable design, improved robustness to variability in magnetization strength, and increased safety during construction. Experimental validation using a prototype magnet shows close agreement with the simulated magnetic field. The Unilateral Linear Halbach magnet increases the sensitivity, portability, and versatility of single-sided NMR. Copyright © 2018 Elsevier Inc. All rights reserved.
International Nuclear Information System (INIS)
Pross, G.
Possibilities of optimizing focus machines with a given energy content in the sense of high neutron yield and high reliability of the discharges are investigated experimentally. For this purpose, a focus machine of the Mather type with an energy content of 12 kJ was constructed. The following experimental parameters were varied: the material of the insulator in the ignition zone, the structure of the outside electrode, the length of the inside electrode, the filling pressure and the amount and polarity of the battery voltage. An important part of the diagnostic program consists of measurements of the azimuthal and axial current distribution in the accelerator, correlated with short-term photographs of the luminous front as a function of time. The results are given. A functional schematic has been drafted for focus discharge as an aid in extensive optimization of focus machines, combining findings from theory and experiments. The schematic takes into account the multiparameter character of the discharge and clarifies relationships between the experimental parameters and the target variables neutron yield and reliability
Xiao, Shou-Ne; Wang, Ming-Meng; Hu, Guang-Zhong; Yang, Guang-Wu
2017-09-01
In view of the problem that it's difficult to accurately grasp the influence range and transmission path of the vehicle top design requirements on the underlying design parameters. Applying directed-weighted complex network to product parameter model is an important method that can clarify the relationships between product parameters and establish the top-down design of a product. The relationships of the product parameters of each node are calculated via a simple path searching algorithm, and the main design parameters are extracted by analysis and comparison. A uniform definition of the index formula for out-in degree can be provided based on the analysis of out-in-degree width and depth and control strength of train carriage body parameters. Vehicle gauge, axle load, crosswind and other parameters with higher values of the out-degree index are the most important boundary conditions; the most considerable performance indices are the parameters that have higher values of the out-in-degree index including torsional stiffness, maximum testing speed, service life of the vehicle, and so on; the main design parameters contain train carriage body weight, train weight per extended metre, train height and other parameters with higher values of the in-degree index. The network not only provides theoretical guidance for exploring the relationship of design parameters, but also further enriches the application of forward design method to high-speed trains.
Directory of Open Access Journals (Sweden)
Shang-Ming Huang
2017-11-01
Full Text Available 2-Ethylhexyl salicylate, an ultraviolet filter, is widely used to protect skin against sunlight-induced harmful effects in the cosmetic industry. In this study, the green synthesis of 2-ethylhexyl salicylate using immobilized lipase through a solvent-free and reduced pressure evaporation system was investigated. A Box–Behnken design was employed to develop an artificial neural network (ANN model. The parameters for an optimal architecture of an ANN were set out: a quick propagation algorithm, a hyperbolic tangent transfer function, 10,000 iterations, and six nodes within the hidden layer. The best-fitting performance of the ANN was determined by the coefficient of determination and the root-mean-square error between the correlation of predicted and experimental data, indicating that the ANN displayed excellent data-fitting properties. Finally, the experimental conditions of synthesis were well established with the optimal parameters to obtain a high conversion of 2-ethylhexyl salicylate. In conclusion, this study efficiently replaces the traditional solvents with a green process for the synthesis of 2-ethylhexyl salicylate to avoid environmental contamination, and this process is well-modeled by a methodological ANN for optimization, which might be a benefit for industrial production.
Directory of Open Access Journals (Sweden)
Iurian S
2017-03-01
Full Text Available Sonia Iurian, Luana Turdean, Ioan Tomuta Department of Pharmaceutical Technology and Biopharmacy, University of Medicine and Pharmacy Iuliu Hatieganu, Cluj-Napoca, Romania Abstract: This study focuses on the development of a drug product based on a risk assessment-based approach, within the quality by design paradigm. A prolonged release system was proposed for paliperidone (Pal delivery, containing Kollidon® SR as an insoluble matrix agent and hydroxypropyl cellulose, hydroxypropyl methylcellulose (HPMC, or sodium carboxymethyl cellulose as a hydrophilic polymer. The experimental part was preceded by the identification of potential sources of variability through Ishikawa diagrams, and failure mode and effects analysis was used to deliver the critical process parameters that were further optimized by design of experiments. A D-optimal design was used to investigate the effects of Kollidon SR ratio (X1, the type of hydrophilic polymer (X2, and the percentage of hydrophilic polymer (X3 on the percentages of dissolved Pal over 24 h (Y1–Y9. Effects expressed as regression coefficients and response surfaces were generated, along with a design space for the preparation of a target formulation in an experimental area with low error risk. The optimal formulation contained 27.62% Kollidon SR and 8.73% HPMC and achieved the prolonged release of Pal, with low burst effect, at ratios that were very close to the ones predicted by the model. Thus, the parameters with the highest impact on the final product quality were studied, and safe ranges were established for their variations. Finally, a risk mitigation and control strategy was proposed to assure the quality of the system, by constant process monitoring. Keywords: pharmaceutical development, quality by design, failure mode effects analysis, Ishikawa diagram, fish-bone diagram, hydrophilic matrix
Optimizing Nuclear Reaction Analysis (NRA) using Bayesian Experimental Design
International Nuclear Information System (INIS)
Toussaint, Udo von; Schwarz-Selinger, Thomas; Gori, Silvio
2008-01-01
Nuclear Reaction Analysis with 3 He holds the promise to measure Deuterium depth profiles up to large depths. However, the extraction of the depth profile from the measured data is an ill-posed inversion problem. Here we demonstrate how Bayesian Experimental Design can be used to optimize the number of measurements as well as the measurement energies to maximize the information gain. Comparison of the inversion properties of the optimized design with standard settings reveals huge possible gains. Application of the posterior sampling method allows to optimize the experimental settings interactively during the measurement process.
Directory of Open Access Journals (Sweden)
M. Franchini
2000-01-01
Full Text Available The sensitivity analysis described in Hashemi et al. (2000 is based on one-at-a-time perturbations to the model parameters. This type of analysis cannot highlight the presence of parameter interactions which might indeed affect the characteristics of the flood frequency curve (ffc even more than the individual parameters. For this reason, the effects of the parameters of the rainfall, rainfall runoff models and of the potential evapotranspiration demand on the ffc are investigated here through an analysis of the results obtained from a factorial experimental design, where all the parameters are allowed to vary simultaneously. This latter, more complex, analysis confirms the results obtained in Hashemi et al. (2000 thus making the conclusions drawn there of wider validity and not related strictly to the reference set selected. However, it is shown that two-factor interactions are present not only between different pairs of parameters of an individual model, but also between pairs of parameters of different models, such as rainfall and rainfall-runoff models, thus demonstrating the complex interaction between climate and basin characteristics affecting the ffc and in particular its curvature. Furthermore, the wider range of climatic regime behaviour produced within the factorial experimental design shows that the probability distribution of soil moisture content at the storm arrival time is no longer sufficient to explain the link between the perturbations to the parameters and their effects on the ffc, as was suggested in Hashemi et al. (2000. Other factors have to be considered, such as the probability distribution of the soil moisture capacity, and the rainfall regime, expressed through the annual maximum rainfalls over different durations. Keywords: Monte Carlo simulation; factorial experimental design; analysis of variance (ANOVA
Optimal Design of Measurement Programs for the Parameter Identification of Dynamic Systems
DEFF Research Database (Denmark)
Kirkegaard, Poul Henning; Sørensen, John Dalsgaard; Brincker, Rune
The design of a measured program devoted to parameter identification of structural dynamic systems is considered, the design problem is formulated as an optimization problem due to minimize the total expected cost of the measurement program. All the calculations are based on a priori knowledge...... and engineering judgement. One of the contribution of the approach is that the optimal nmber of sensors can be estimated. This is sown in an numerical example where the proposed approach is demonstrated. The example is concerned with design of a measurement program for estimating the modal damping parameters...
A Laplace method for under-determined Bayesian optimal experimental designs
Long, Quan; Scavino, Marco; Tempone, Raul; Wang, Suojin
2014-01-01
In Long et al. (2013), a new method based on the Laplace approximation was developed to accelerate the estimation of the post-experimental expected information gains (Kullback–Leibler divergence) in model parameters and predictive quantities
International Nuclear Information System (INIS)
Cuce, Erdem; Cuce, Pinar Mert; Bali, Tulin
2013-01-01
Highlights: • R sh is rather sensitive to the variations in T c . • For higher G values, G ∗ is not affected from the variations in light intensity. • Ideality factor decreases linearly with increasing T c . • A linear decrease of R s and R sh has been observed with increasing T c . • Fill factor increases exponentially with G while it decreases linearly with T c . - Abstract: It is well known that accurate knowledge of photovoltaic cell parameters from the measured current–voltage characteristics is of vital importance for the quality control and the performance assessment of photovoltaic cells/modules. Although many attempts have been made so far for a thorough analysis of cell parameters, there are still significant discrepancies between the previously published results. In this regard, a detailed investigation of cell parameters through a comprehensive experimental and statistical work is important to elucidate the aforementioned contradictions. Therefore in the present work, effects of two main environmental factors on performance parameters of mono-crystalline and poly-crystalline silicon photovoltaic modules have been experimentally investigated. The experiments have been carried out under a calibrated solar simulator for various intensity levels and cell temperatures in the range 200–500 W/m 2 and 15–60 °C, respectively. The results indicated that light intensity has a dominant effect on current parameters. Photocurrent, short circuit current and maximum current increase linearly with increasing intensity level. A new term, solar intensity coefficient, has been defined first time to characterize the solar radiation dependency of current parameters. On the other hand, it has been observed that cell temperature has a dramatic effect on voltage parameters. Open circuit voltage and maximum voltage considerably decrease with increasing cell temperature. Temperature coefficients of voltage parameters have been calculated for each case. Shunt
Visualizing Experimental Designs for Balanced ANOVA Models using Lisp-Stat
Directory of Open Access Journals (Sweden)
Philip W. Iversen
2004-12-01
Full Text Available The structure, or Hasse, diagram described by Taylor and Hilton (1981, American Statistician provides a visual display of the relationships between factors for balanced complete experimental designs. Using the Hasse diagram, rules exist for determining the appropriate linear model, ANOVA table, expected means squares, and F-tests in the case of balanced designs. This procedure has been implemented in Lisp-Stat using a software representation of the experimental design. The user can interact with the Hasse diagram to add, change, or delete factors and see the effect on the proposed analysis. The system has potential uses in teaching and consulting.
Fundamentals of statistical experimental design and analysis
Easterling, Robert G
2015-01-01
Professionals in all areas - business; government; the physical, life, and social sciences; engineering; medicine, etc. - benefit from using statistical experimental design to better understand their worlds and then use that understanding to improve the products, processes, and programs they are responsible for. This book aims to provide the practitioners of tomorrow with a memorable, easy to read, engaging guide to statistics and experimental design. This book uses examples, drawn from a variety of established texts, and embeds them in a business or scientific context, seasoned with a dash of humor, to emphasize the issues and ideas that led to the experiment and the what-do-we-do-next? steps after the experiment. Graphical data displays are emphasized as means of discovery and communication and formulas are minimized, with a focus on interpreting the results that software produce. The role of subject-matter knowledge, and passion, is also illustrated. The examples do not require specialized knowledge, and t...
Development of a parameter optimization technique for the design of automatic control systems
Whitaker, P. H.
1977-01-01
Parameter optimization techniques for the design of linear automatic control systems that are applicable to both continuous and digital systems are described. The model performance index is used as the optimization criterion because of the physical insight that can be attached to it. The design emphasis is to start with the simplest system configuration that experience indicates would be practical. Design parameters are specified, and a digital computer program is used to select that set of parameter values which minimizes the performance index. The resulting design is examined, and complexity, through the use of more complex information processing or more feedback paths, is added only if performance fails to meet operational specifications. System performance specifications are assumed to be such that the desired step function time response of the system can be inferred.
Safety parameter display system (SPDS) for Russian-designed NPPs
International Nuclear Information System (INIS)
Anikanov, S.S.; Catullo, W.J.; Pelusi, J.L.
1997-01-01
As part of the programs aimed at improving the safety of Russian-designed reactors, the US DoE has sponsored a project of providing a safety parameter display system (SPDS) for nuclear power plants with such reactors. The present paper is focused mostly on the system architecture design features of SPDS systems for WWER-1000 and RBMK-1000 reactors. The function and the operating modes of the SPDS are outlined, and a description of the display system is given. The system architecture and system design of both an integrated and a stand-alone IandC system is explained. (A.K.)
Experimental determination of lattice parameters for 2% enriched uranium heavy water reactor cores
Energy Technology Data Exchange (ETDEWEB)
Raisic, N; Takac, S; Markovic, H; Bosevski, T [Boris Kidric Institute of Nuclear Sciences Vinca, Belgrade (Yugoslavia)
1963-04-15
Systematic measurements of the buckling, infinite multiplication factor and the thermal utilization factor were made on a series of lattices for 2% enriched uranium tubular fuel elements in heavy water. This work represents the first phase of experimental verification of standard theoretical methods used for the determination of reactor parameters.
Termini, Donatella
2013-04-01
Recent catastrophic events due to intense rainfalls have mobilized large amount of sediments causing extensive damages in vast areas. These events have highlighted how debris-flows runout estimations are of crucial importance to delineate the potentially hazardous areas and to make reliable assessment of the level of risk of the territory. Especially in recent years, several researches have been conducted in order to define predicitive models. But, existing runout estimation methods need input parameters that can be difficult to estimate. Recent experimental researches have also allowed the assessment of the physics of the debris flows. But, the major part of the experimental studies analyze the basic kinematic conditions which determine the phenomenon evolution. Experimental program has been recently conducted at the Hydraulic laboratory of the Department of Civil, Environmental, Aerospatial and of Materials (DICAM) - University of Palermo (Italy). The experiments, carried out in a laboratory flume appositely constructed, were planned in order to evaluate the influence of different geometrical parameters (such as the slope and the geometrical characteristics of the confluences to the main channel) on the propagation phenomenon of the debris flow and its deposition. Thus, the aim of the present work is to give a contribution to defining input parameters in runout estimation by numerical modeling. The propagation phenomenon is analyzed for different concentrations of solid materials. Particular attention is devoted to the identification of the stopping distance of the debris flow and of the involved parameters (volume, angle of depositions, type of material) in the empirical predictive equations available in literature (Rickenmanm, 1999; Bethurst et al. 1997). Bethurst J.C., Burton A., Ward T.J. 1997. Debris flow run-out and landslide sediment delivery model tests. Journal of hydraulic Engineering, ASCE, 123(5), 419-429 Rickenmann D. 1999. Empirical relationships
Summary of the experimental multi-purpose very high temperature gas cooled reactor design
International Nuclear Information System (INIS)
1984-12-01
The report presents the design of Multi-purpose Very High Temperature Gas Cooled Reactor (the Experimental VHTR) based on the second stage of detailed design which was completed on March 1984, in the from of ''An application of reactor construction permit Appendix 8''. The Experimental VHTR is designed to satisfy with the design specification for the reactor thermal output 50 MW and reactor outlet temperature 950 0 C. The adequacy of the design is also checked by the safety analysis. The planning of plant system and safety is summarized such as safety design requirements and conformance with them, seismic design and plant arrangement. Concerning with the system of the Experimental VHTR the design basis, design data and components are described in the order. (author)
Design Issues and Inference in Experimental L2 Research
Hudson, Thom; Llosa, Lorena
2015-01-01
Explicit attention to research design issues is essential in experimental second language (L2) research. Too often, however, such careful attention is not paid. This article examines some of the issues surrounding experimental L2 research and its relationships to causal inferences. It discusses the place of research questions and hypotheses,…
Use of Experimental Design for Peuhl Cheese Process Optimization ...
African Journals Online (AJOL)
Use of Experimental Design for Peuhl Cheese Process Optimization. ... Journal of Applied Sciences and Environmental Management ... This work consisting in use of a central composite design enables the determination of optimal process conditions concerning: leaf extract volume added (7 mL), heating temperature ...
Experimentally supported control design for a direct drive robot
Kostic, D.; Jager, de A.G.; Steinbuch, M.
2002-01-01
We promote the idea of an experimentally supported control design as a successful way to achieve accurate tracking of reference robot motions, under disturbance conditions and given the uncertainties arising from modeling errors. The Hinf robust control theory is used for design of motion
International Nuclear Information System (INIS)
Kim, Yong Il; Choi, Chan Kyu; Yoo, Hong Hee
2012-01-01
For the design of a MEMS accelerometer, proper performance indices should be defined and employed. Performance indices are obtained using either an experimental method or a numerical method. In the present study, a vibration analysis model of a MEMS accelerometer is introduced to calculate three performance indices: sensitivity, measurable acceleration range, and measurable frequency range. The accuracy of the vibration analysis model is first validated by comparing its modal and transient results with those of a commercial finite element code. Measurable acceleration and frequency ranges versus allowable errors for electrical and mechanical sensitivities are obtained and the effects of system parameter variations on the three performance indices are investigated
Directory of Open Access Journals (Sweden)
Hadidi N
2011-04-01
Full Text Available Naghmeh Hadidi1, Farzad Kobarfard2, Nastaran Nafissi-Varcheh3, Reza Aboofazeli11Department of Pharmaceutics, 2Department of Pharmaceutical Chemistry, 3Department of Pharmaceutical Biotechnology, School of Pharmacy, Shaheed Beheshti University of Medical Sciences, Tehran, IranAbstract: In this study, noncovalent functionalization of single-walled carbon nanotubes (SWCNTs with phospholipid-polyethylene glycols (Pl-PEGs was performed to improve the solubility of SWCNTs in aqueous solution. Two kinds of PEG derivatives, ie, Pl-PEG 2000 and Pl-PEG 5000, were used for the PEGylation process. An experimental design technique (D-optimal design and second-order polynomial equations was applied to investigate the effect of variables on PEGylation and the solubility of SWCNTs. The type of PEG derivative was selected as a qualitative parameter, and the PEG/SWCNT weight ratio and sonication time were applied as quantitative variables for the experimental design. Optimization was performed for two responses, aqueous solubility and loading efficiency. The grafting of PEG to the carbon nanostructure was determined by thermogravimetric analysis, Raman spectroscopy, and scanning electron microscopy. Aqueous solubility and loading efficiency were determined by ultraviolet-visible spectrophotometry and measurement of free amine groups, respectively. Results showed that Pl-PEGs were grafted onto SWCNTs. Aqueous solubility of 0.84 mg/mL and loading efficiency of nearly 98% were achieved for the prepared Pl-PEG 5000-SWCNT conjugates. Evaluation of functionalized SWCNTs showed that our noncovalent functionalization protocol could considerably increase aqueous solubility, which is an essential criterion in the design of a carbon nanotube-based drug delivery system and its biodistribution.Keywords: phospholipid-PEG, D-optimal design, loading efficiency, Raman spectroscopy, scanning electron microscopy, theromogravimetric analysis, carbon nanotubes
Design of a multi beam klystron cavity from its single beam parameters
Energy Technology Data Exchange (ETDEWEB)
Kant, Deepender, E-mail: dkc@ceeri.ernet.in; Joshi, L. M. [CSIR-Central Electronics Engineering Research Institute, Pilani (India); Janyani, Vijay [Department of ECE, MNIT, Jaipur (India)
2016-03-09
The klystron is a well-known microwave amplifier which uses kinetic energy of an electron beam for amplification of the RF signal. There are some limitations of conventional single beam klystron such as high operating voltage, low efficiency and bulky size at higher power levels, which are very effectively handled in Multi Beam Klystron (MBK) that uses multiple low purveyance electron beams for RF interaction. Each beam propagates along its individual transit path through a resonant cavity structure. Multi-Beam klystron cavity design is a critical task due to asymmetric cavity structure and can be simulated by 3D code only. The present paper shall discuss the design of multi beam RF cavities for klystrons operating at 2856 MHz (S-band) and 5 GHz (C-band) respectively. The design approach uses some scaling laws for finding the electron beam parameters of the multi beam device from their single beam counter parts. The scaled beam parameters are then used for finding the design parameters of the multi beam cavities. Design of the desired multi beam cavity can be optimized through iterative simulations in CST Microwave Studio.
Design of a multi beam klystron cavity from its single beam parameters
International Nuclear Information System (INIS)
Kant, Deepender; Joshi, L. M.; Janyani, Vijay
2016-01-01
The klystron is a well-known microwave amplifier which uses kinetic energy of an electron beam for amplification of the RF signal. There are some limitations of conventional single beam klystron such as high operating voltage, low efficiency and bulky size at higher power levels, which are very effectively handled in Multi Beam Klystron (MBK) that uses multiple low purveyance electron beams for RF interaction. Each beam propagates along its individual transit path through a resonant cavity structure. Multi-Beam klystron cavity design is a critical task due to asymmetric cavity structure and can be simulated by 3D code only. The present paper shall discuss the design of multi beam RF cavities for klystrons operating at 2856 MHz (S-band) and 5 GHz (C-band) respectively. The design approach uses some scaling laws for finding the electron beam parameters of the multi beam device from their single beam counter parts. The scaled beam parameters are then used for finding the design parameters of the multi beam cavities. Design of the desired multi beam cavity can be optimized through iterative simulations in CST Microwave Studio.
Dasgupta, Annwesa P.; Anderson, Trevor R.
2014-01-01
It is essential to teach students about experimental design, as this facilitates their deeper understanding of how most biological knowledge was generated and gives them tools to perform their own investigations. Despite the importance of this area, surprisingly little is known about what students actually learn from designing biological experiments. In this paper, we describe a rubric for experimental design (RED) that can be used to measure knowledge of and diagnose difficulties with experimental design. The development and validation of the RED was informed by a literature review and empirical analysis of undergraduate biology students’ responses to three published assessments. Five areas of difficulty with experimental design were identified: the variable properties of an experimental subject; the manipulated variables; measurement of outcomes; accounting for variability; and the scope of inference appropriate for experimental findings. Our findings revealed that some difficulties, documented some 50 yr ago, still exist among our undergraduate students, while others remain poorly investigated. The RED shows great promise for diagnosing students’ experimental design knowledge in lecture settings, laboratory courses, research internships, and course-based undergraduate research experiences. It also shows potential for guiding the development and selection of assessment and instructional activities that foster experimental design. PMID:26086658
Application of Factorial Design for Gas Parameter Optimization in CO2 Laser Welding
DEFF Research Database (Denmark)
Gong, Hui; Dragsted, Birgitte; Olsen, Flemming Ove
1997-01-01
The effect of different gas process parameters involved in CO2 laser welding has been studied by applying two-set of three-level complete factorial designs. In this work 5 gas parameters, gas type, gas flow rate, gas blowing angle, gas nozzle diameter, gas blowing point-offset, are optimized...... to be a very useful tool for parameter optimi-zation in laser welding process. Keywords: CO2 laser welding, gas parameters, factorial design, Analysis of Variance........ The bead-on-plate welding specimens are evaluated by a number of quality char-acteristics, such as the penetration depth and the seam width. The significance of the gas pa-rameters and their interactions are based on the data found by the Analysis of Variance-ANOVA. This statistic methodology is proven...
Conceptual design of fusion experimental reactor (FER)
International Nuclear Information System (INIS)
1984-03-01
A conceptual design study (option C) has been carried out for the fusion experimental reactor (FER). In addition to design of the tokamak reactor and associated systems based on the reference design specifications, feasibility of a water-shield reactor concept was examined as a topical study. The design study for the reference tokamak reactor has produced a reactor concept for the FER, along with major R D items for the concept, based on close examinations on thermal design, electromagnetics, neutronics and remote maintenance. Particular efforts have been directed to the area of electromagnetics. Detailed analyses with close simulation models have been performed on PF coil arrangements and configurations, shell effects of the blanket for plasma position unstability, feedback control, and eddy currents during disruptions. The major design specifications are as follows; Peak fusion power 437 MW Major radius 5.5 m Minor radius 1.1 m Plasma elongation 1.5 Plasma current 5.3 MA Toroidal beta 4 % Field on axis 5.7 T (author)
Wang, Kewu; Xiao, Shengxiang; Jiang, Lina; Hu, Jingkai
2017-09-30
In order to regularly detect the performance parameters of automated external defibrillator (AED), to make sure it is safe before using the instrument, research and design of a system for detecting automated external defibrillator performance parameters. According to the research of the characteristics of its performance parameters, combing the STM32's stability and high speed with PWM modulation control, the system produces a variety of ECG normal and abnormal signals through the digital sampling methods. Completed the design of the hardware and software, formed a prototype. This system can accurate detect automated external defibrillator discharge energy, synchronous defibrillation time, charging time and other key performance parameters.
Gandolfi, F; Malleret, L; Sergent, M; Doumenq, P
2015-08-07
The water framework directives (WFD 2000/60/EC and 2013/39/EU) force European countries to monitor the quality of their aquatic environment. Among the priority hazardous substances targeted by the WFD, short chain chlorinated paraffins C10-C13 (SCCPs), still represent an analytical challenge, because few laboratories are nowadays able to analyze them. Moreover, an annual average quality standards as low as 0.4μgL(-1) was set for SCCPs in surface water. Therefore, to test for compliance, the implementation of sensitive and reliable analysis method of SCCPs in water are required. The aim of this work was to address this issue by evaluating automated solid phase micro-extraction (SPME) combined on line with gas chromatography-electron capture negative ionization mass spectrometry (GC/ECNI-MS). Fiber polymer, extraction mode, ionic strength, extraction temperature and time were the most significant thermodynamic and kinetic parameters studied. To determine the suitable factors working ranges, the study of the extraction conditions was first carried out by using a classical one factor-at-a-time approach. Then a mixed level factorial 3×2(3) design was performed, in order to give rise to the most influent parameters and to estimate potential interactions effects between them. The most influent factors, i.e. extraction temperature and duration, were optimized by using a second experimental design, in order to maximize the chromatographic response. At the close of the study, a method involving headspace SPME (HS-SPME) coupled to GC/ECNI-MS is proposed. The optimum extraction conditions were sample temperature 90°C, extraction time 80min, with the PDMS 100μm fiber and desorption at 250°C during 2min. Linear response from 0.2ngmL(-1) to 10ngmL(-1) with r(2)=0.99 and limits of detection and quantification, respectively of 4pgmL(-1) and 120pgmL(-1) in MilliQ water, were achieved. The method proved to be applicable in different types of waters and show key advantages, such
DUINEVELD, CAA; SMILDE, AK; DOORNBOS, DA
The combination of process variables and mixture variables in experimental design is a problem which has not yet been solved. It is examined here whether a set of designs can be found which can be used for a series of models of reasonable complexity. The proposed designs are compared with known
DUINEVELD, C. A. A.; Smilde, A. K.; Doornbos, D. A.
1993-01-01
The combination of process variables and mixture variables in experimental design is a problem which has not yet been solved. It is examined here whether a set of designs can be found which can be used for a series of models of reasonable complexity. The proposed designs are compared with known
An Experimental Verification of morphology of ibuprofen crystals from CAMD designed solvent
DEFF Research Database (Denmark)
Karunanithi, Arunprakash T.; Acquah, Charles; Achenie, Luke E.K.
2007-01-01
of crystals formed from solvents, necessitates additional experimental verification steps. In this work we report the experimental verification of crystal morphology for the case study, solvent design for ibuprofen crystallization, presented in Karunanithi et al. [2006. A computer-aided molecular design...
Design and experimental characterization of an EM pump
International Nuclear Information System (INIS)
Kim, Hee Reyoung; Hong, Sang Hee
1999-01-01
Generally, an EM (electromagnetic) pump is been employed to circulate electrically conducting liquids by using the Lorentz force. Especially, at the liquid metal reactor (LMR), which uses liquid sodium with high electrical conductivity as a coolant, an EM pump is needed due to its advantages over a mechanical pump, such as no rotating parts, no noise, and simplicity. In this research, an EM pump of a pilot annular linear induction type with a flow rate of 200 l/min was designed by using the electrical equivalent-circuit method. The pump was designed and manufactured by considering material and environmental (high temperature and liquid sodium) requirements. The pump performance was experimentally characterized based on input currents, voltage, power, and frequency. Also, the theoretical prediction was compared with the experimental result
Experimental Design for Hanford Low-Activity Waste Glasses with High Waste Loading
International Nuclear Information System (INIS)
Piepel, Gregory F.; Cooley, Scott K.; Vienna, John D.; Crum, Jarrod V.
2015-01-01
This report discusses the development of an experimental design for the initial phase of the Hanford low-activity waste (LAW) enhanced glass study. This report is based on a manuscript written for an applied statistics journal. Appendices A, B, and E include additional information relevant to the LAW enhanced glass experimental design that is not included in the journal manuscript. The glass composition experimental region is defined by single-component constraints (SCCs), linear multiple-component constraints (MCCs), and a nonlinear MCC involving 15 LAW glass components. Traditional methods and software for designing constrained mixture experiments with SCCs and linear MCCs are not directly applicable because of the nonlinear MCC. A modification of existing methodology to account for the nonlinear MCC was developed and is described in this report. One of the glass components, SO 3 , has a solubility limit in glass that depends on the composition of the balance of the glass. A goal was to design the experiment so that SO 3 would not exceed its predicted solubility limit for any of the experimental glasses. The SO 3 solubility limit had previously been modeled by a partial quadratic mixture model expressed in the relative proportions of the 14 other components. The partial quadratic mixture model was used to construct a nonlinear MCC in terms of all 15 components. In addition, there were SCCs and linear MCCs. This report describes how a layered design was generated to (i) account for the SCCs, linear MCCs, and nonlinear MCC and (ii) meet the goals of the study. A layered design consists of points on an outer layer, and inner layer, and a center point. There were 18 outer-layer glasses chosen using optimal experimental design software to augment 147 existing glass compositions that were within the LAW glass composition experimental region. Then 13 inner-layer glasses were chosen with the software to augment the existing and outer-layer glasses. The experimental
Parameters and design optimization of the ring piezoelectric ceramic transformer
Directory of Open Access Journals (Sweden)
Jiří Erhart
2015-09-01
Full Text Available Main aim of the presented paper is the theoretical analysis and experimental verification of the transformation parameters for the new type of nonhomogeneously poled ring transformer. The input part is poled in the thickness direction and output part in the radial direction. Two transformer geometries are studied — the input part is at inner ring segment, or it is at the outer ring segment. The optimum electrode size aspect ratios have been found experimentally as d1∕D≈0.60−0.65 for the ring with aspect ratio d∕D=0.2. The fundamental as well as higher overtone resonances were studied for the transformation ratio, the optimum resistive load, efficiency and no-load transformation ratio. Higher overtones have better transformation parameters compared to the fundamental resonance. The new type ring transformer exhibits very high transformation ratios up to 200 under no-load and up to 13.4 under a high efficiency of 97% at the optimum load conditions of 10 kΩ. Strong electric field gradient at the output circuit is applicable for the electrical discharge generation.
COMPUTER-AIDED DESIGN, MANUFACTURE AND EXPERIMENTAL ANALYSIS OF A PAIR OF ELLIPTICAL SPUR GEARS
Directory of Open Access Journals (Sweden)
Mehmet YAZAR
2016-12-01
Full Text Available ABSTRACT In this study, geometrical equations of elliptical spur gears, which are too difficult to manufacture by traditional methods and which require specific machines equipped with special techniques, are developed using the methods in the literature. Using these equations, a LISP program on AutoLISP is created to model elliptical spur gears on AutoCAD with desired tooth number and modules. Elliptical spur gears are manufactured with 5 different modules by Wire EDM through the above-mentioned package program. The variations in the center distances of elliptical spur gears, the most important parameter for workability of gears, are experimentally determined by a simple test unit designed and manufactured within the context this study. In addition, the surface roughness and hardness of elliptical spur gears are obtained and hydraulic pump and noise analysis results are discussed. The experimental and computer-aided results show that the elliptical spur gears may widely be used in many industrial and mechanical applications in the future.
Conceptual design of fusion experimental reactor (FER)
International Nuclear Information System (INIS)
1984-02-01
This report describes the engineering conceptual design of Fusion Experimental Reactor (FER) which is to be built as a next generation tokamak machine. This design covers overall reactor systems including MHD equilibrium analysis, mechanical configuration of reactor, divertor, pumped limiter, first wall/breeding blanket/shield, toroidal field magnet, poloidal field magnet, cryostat, electromagnetic analysis, vacuum system, power handling and conversion, NBI, RF heating device, tritium system, neutronics, maintenance, cooling system and layout of facilities. The engineering comparison of a divertor with pumped limiters and safety analysis of reactor systems are also conducted. (author)
Fast Bayesian optimal experimental design and its applications
Long, Quan
2015-01-01
We summarize our Laplace method and multilevel method of accelerating the computation of the expected information gain in a Bayesian Optimal Experimental Design (OED). Laplace method is a widely-used method to approximate an integration
Structural parameter optimization design for Halbach permanent maglev rail
International Nuclear Information System (INIS)
Guo, F.; Tang, Y.; Ren, L.; Li, J.
2010-01-01
Maglev rail is an important part of the magnetic levitation launch system. Reducing the manufacturing cost of magnetic levitation rail is the key problem for the development of magnetic levitation launch system. The Halbach permanent array has an advantage that the fundamental spatial field is cancelled on one side of the array while the field on the other side is enhanced. So this array used in the design of high temperature superconducting permanent maglev rail could improve the surface magnetic field and the levitation force. In order to make the best use of Nd-Fe-B (NdFeB) material and reduce the cost of maglev rail, the effect of the rail's structural parameters on levitation force and the utilization rate of NdFeB material are analyzed. The optimal ranges of these structural parameters are obtained. The mutual impact of these parameters is also discussed. The optimization method of these structure parameters is proposed at the end of this paper.
Structural parameter optimization design for Halbach permanent maglev rail
Energy Technology Data Exchange (ETDEWEB)
Guo, F., E-mail: guofang19830119@163.co [R and D Center of Applied Superconductivity, Huazhong University of Science and Technology, Wuhan 430074 (China); Tang, Y.; Ren, L.; Li, J. [R and D Center of Applied Superconductivity, Huazhong University of Science and Technology, Wuhan 430074 (China)
2010-11-01
Maglev rail is an important part of the magnetic levitation launch system. Reducing the manufacturing cost of magnetic levitation rail is the key problem for the development of magnetic levitation launch system. The Halbach permanent array has an advantage that the fundamental spatial field is cancelled on one side of the array while the field on the other side is enhanced. So this array used in the design of high temperature superconducting permanent maglev rail could improve the surface magnetic field and the levitation force. In order to make the best use of Nd-Fe-B (NdFeB) material and reduce the cost of maglev rail, the effect of the rail's structural parameters on levitation force and the utilization rate of NdFeB material are analyzed. The optimal ranges of these structural parameters are obtained. The mutual impact of these parameters is also discussed. The optimization method of these structure parameters is proposed at the end of this paper.
International Nuclear Information System (INIS)
Guseva, E.V.; Peregudov, V.N.
1982-01-01
The FITGAV program for calculation of parameters of the Gauss curve describing experimental data is considered. The calculations are based on the least square fit method. The estimations of errors in the parameter determination as a function of experimental data sample volume and their statistical significance are obtained. The curve fit using 100 points occupies less than 1 s at the SM-4 type computer
Directory of Open Access Journals (Sweden)
Damilola Isaac Adebiyi
2016-06-01
Full Text Available The cold spray coating process involves many process parameters which make the process very complex, and highly dependent and sensitive to small changes in these parameters. This results in a small operational window of the parameters. Consequently, mathematical optimization of the process parameters is key, not only to achieving deposition but also improving the coating quality. This study focuses on the mathematical identification and experimental justification of the optimum process parameters for cold spray coating of titanium alloy with silicon carbide (SiC. The continuity, momentum and the energy equations governing the flow through the low-pressure cold spray nozzle were solved by introducing a constitutive equation to close the system. This was used to calculate the critical velocity for the deposition of SiC. In order to determine the input temperature that yields the calculated velocity, the distribution of velocity, temperature, and pressure in the cold spray nozzle were analyzed, and the exit values were predicted using the meshing tool of Solidworks. Coatings fabricated using the optimized parameters and some non-optimized parameters are compared. The coating of the CFD-optimized parameters yielded lower porosity and higher hardness.
Optimal Experimental Design of Furan Shock Tube Kinetic Experiments
Kim, Daesang
2015-01-07
A Bayesian optimal experimental design methodology has been developed and applied to refine the rate coefficients of elementary reactions in Furan combustion. Furans are considered as potential renewable fuels. We focus on the Arrhenius rates of Furan + OH ↔ Furyl-2 + H2O and Furan ↔ OH Furyl-3 + H2O, and rely on the OH consumption rate as experimental observable. A polynomial chaos surrogate is first constructed using an adaptive pseudo-spectral projection algorithm. The PC surrogate is then exploited in conjunction with a fast estimation of the expected information gain in order to determine the optimal design in the space of initial temperatures and OH concentrations.
Experimental design and quantitative analysis of microbial community multiomics.
Mallick, Himel; Ma, Siyuan; Franzosa, Eric A; Vatanen, Tommi; Morgan, Xochitl C; Huttenhower, Curtis
2017-11-30
Studies of the microbiome have become increasingly sophisticated, and multiple sequence-based, molecular methods as well as culture-based methods exist for population-scale microbiome profiles. To link the resulting host and microbial data types to human health, several experimental design considerations, data analysis challenges, and statistical epidemiological approaches must be addressed. Here, we survey current best practices for experimental design in microbiome molecular epidemiology, including technologies for generating, analyzing, and integrating microbiome multiomics data. We highlight studies that have identified molecular bioactives that influence human health, and we suggest steps for scaling translational microbiome research to high-throughput target discovery across large populations.
DEFF Research Database (Denmark)
Hartmann, Hannes; Popok, Vladimir; Barke, Ingo
2012-01-01
The design and performance of an experimental setup utilizing a magnetron sputtering source for production of beams of ionized size-selected clusters for deposition in ultra-high vacuum is described. For the case of copper cluster formation the influence of different source parameters is studied...
Sanchez, Gaëtan; Lecaignard, Françoise; Otman, Anatole; Maby, Emmanuel; Mattout, Jérémie
2016-01-01
The relatively young field of Brain-Computer Interfaces has promoted the use of electrophysiology and neuroimaging in real-time. In the meantime, cognitive neuroscience studies, which make extensive use of functional exploration techniques, have evolved toward model-based experiments and fine hypothesis testing protocols. Although these two developments are mostly unrelated, we argue that, brought together, they may trigger an important shift in the way experimental paradigms are being designed, which should prove fruitful to both endeavors. This change simply consists in using real-time neuroimaging in order to optimize advanced neurocognitive hypothesis testing. We refer to this new approach as the instantiation of an Active SAmpling Protocol (ASAP). As opposed to classical (static) experimental protocols, ASAP implements online model comparison, enabling the optimization of design parameters (e.g., stimuli) during the course of data acquisition. This follows the well-known principle of sequential hypothesis testing. What is radically new, however, is our ability to perform online processing of the huge amount of complex data that brain imaging techniques provide. This is all the more relevant at a time when physiological and psychological processes are beginning to be approached using more realistic, generative models which may be difficult to tease apart empirically. Based upon Bayesian inference, ASAP proposes a generic and principled way to optimize experimental design adaptively. In this perspective paper, we summarize the main steps in ASAP. Using synthetic data we illustrate its superiority in selecting the right perceptual model compared to a classical design. Finally, we briefly discuss its future potential for basic and clinical neuroscience as well as some remaining challenges.
Directory of Open Access Journals (Sweden)
B. Nkakanou
2011-01-01
Full Text Available Experimental results for an ultra-wideband (UWB channel parameters in an underground mining environment over a frequency range of 3 GHz to 10 GHz are reported. The measurements were taken both in LOS and NLOS cases in two different size mine galleries. In the NLOS case, results were acquired for different corridor obstruction angles. The results were obtained during an extensive measurement campaign in the UWB frequency, and the measurement procedure allows both the large- and small-scale parameters such as the path loss exponent, coherence bandwidth, and so forth, to be quantified. The capacity of the UWB channel as a function of the physical depth of the mine gallery has also been recorded for comparison purposes.
Importance of helical pitch parameter in LHD-type heliotron reactor designs
International Nuclear Information System (INIS)
Goto, T.; Suzuki, Y.; Yanagi, N.; Watanabe, K.Y.; Imagawa, S.; Sagara, A.
2010-11-01
In the design studies of the LHD-type heliotron reactors, one of the key issues is to secure sufficient blanket spaces. In this respect, helical pitch parameter γ is quite important because it significantly affects both the coil and plasma shapes. In order to understand the effect of helical pitch parameter on the design window quantitatively, a system design code for the LHD-type heliotron reactors has been developed and parametric scans were carried out with 3 cases of γ=1.15, 1.20 and 1.25. It becomes clear that the possible design window of heliotron reactors strongly depends on the engineering constraints: stored magnetic energy of coil system, blanket space, and neutron wall load. γ=1.20 is optimum from the viewpoint of moderating the physics requirements, but γ=1.15 has a robustness to the change in the physics and engineering conditions. Since the design windows are quite sensitive to the engineering constraints and physics conditions, the further detailed study on design feasibility of advanced engineering components and the effect of γ on the physics conditions is expected to optimize the value of γ. (author)
Impact parameter sensitive study of inner-shell atomic processes in the experimental storage ring
Gumberidze, A.; Kozhuharov, C.; Zhang, R. T.; Trotsenko, S.; Kozhedub, Y. S.; DuBois, R. D.; Beyer, H. F.; Blumenhagen, K.-H.; Brandau, C.; Bräuning-Demian, A.; Chen, W.; Forstner, O.; Gao, B.; Gassner, T.; Grisenti, R. E.; Hagmann, S.; Hillenbrand, P.-M.; Indelicato, P.; Kumar, A.; Lestinsky, M.; Litvinov, Yu. A.; Petridis, N.; Schury, D.; Spillmann, U.; Trageser, C.; Trassinelli, M.; Tu, X.; Stöhlker, Th.
2017-10-01
In this work, we present a pilot experiment in the experimental storage ring (ESR) at GSI devoted to impact parameter sensitive studies of inner shell atomic processes for low-energy (heavy-) ion-atom collisions. The experiment was performed with bare and He-like xenon ions (Xe54+, Xe52+) colliding with neutral xenon gas atoms, resulting in a symmetric collision system. This choice of the projectile charge states was made in order to compare the effect of a filled K-shell with the empty one. The projectile and target X-rays have been measured at different observation angles for all impact parameters as well as for the impact parameter range of ∼35-70 fm.
Identifiability and error minimization of receptor model parameters with PET
International Nuclear Information System (INIS)
Delforge, J.; Syrota, A.; Mazoyer, B.M.
1989-01-01
The identifiability problem and the general framework for experimental design optimization are presented. The methodology is applied to the problem of the receptor-ligand model parameter estimation with dynamic positron emission tomography data. The first attempts to identify the model parameters from data obtained with a single tracer injection led to disappointing numerical results. The possibility of improving parameter estimation using a new experimental design combining an injection of the labelled ligand and an injection of the cold ligand (displacement experiment) has been investigated. However, this second protocol led to two very different numerical solutions and it was necessary to demonstrate which solution was biologically valid. This has been possible by using a third protocol including both a displacement and a co-injection experiment. (authors). 16 refs.; 14 figs
Experimental estimations of the kinetics parameters of the IBR-2M reactor by stochastic noises
International Nuclear Information System (INIS)
Pepelyshev, Yu.N.; Tajybov, L.A.; Garibov, A.A.; Mekhtieva, R.N.
2012-01-01
Experimental investigations of stochastic fluctuations of pulse energy of the IBR-2M reactor have been carried out which allowed us to obtain some of the parameters of the reactor kinetics. At different levels of average power a sequence of values of pulse energy was recorded with the calculation of the distribution parameters. An ionization chamber with boron installed near the active zone was used as a neutron detector. The research results allowed us to estimate the average lifetime of prompt neutrons τ = (6.53±0.2)·10 -8 s, absolute power of the reactor and intensity of the source of spontaneous neutrons S sp ≤(6.72±0.12)·10 6 s -1 . It was shown that the experimental results are close to the calculated ones
Moeyaert, Mariola; Ugille, Maaike; Ferron, John M; Beretvas, S Natasha; Van den Noortgate, Wim
2014-09-01
The quantitative methods for analyzing single-subject experimental data have expanded during the last decade, including the use of regression models to statistically analyze the data, but still a lot of questions remain. One question is how to specify predictors in a regression model to account for the specifics of the design and estimate the effect size of interest. These quantitative effect sizes are used in retrospective analyses and allow synthesis of single-subject experimental study results which is informative for evidence-based decision making, research and theory building, and policy discussions. We discuss different design matrices that can be used for the most common single-subject experimental designs (SSEDs), namely, the multiple-baseline designs, reversal designs, and alternating treatment designs, and provide empirical illustrations. The purpose of this article is to guide single-subject experimental data analysts interested in analyzing and meta-analyzing SSED data. © The Author(s) 2014.
Nuclear design of the blanket/shield system for a Tokamak Experimental Power Reactor
International Nuclear Information System (INIS)
Abdou, M.A.
1976-01-01
The various options and trade-offs in the nuclear design of the blanket/shield for a Tokamak Experimental Power Reactor (TEPR) are investigated. The TEPR size and cost are particularly sensitive to the blanket/shield thickness, Δ/sub BS/, on the inner side of the torus. Radition damage to the components of the superconducting magnet and refrigeration power requirements set lower limits on Δ/sub BS/. These limits are developed in terms of TEPR design parameters such as the wall loading, duty cycle, and frequency of magnet anneals. The study of the nuclear performance of various material compositions shows that mixtures of tungsten, or tantalum, or stainless-steel alloys and boron carbide require the smallest Δ/sub BS/ for a given attenuation. This Δ/sub BS/ has to be doubled if the low induced activation materials graphite and aluminum are used. The space problems are greatly eased in the Argonne National Laboratory ANL-TEPR reference design by using two separate segments of the blanket/shield. The inner segment occupies the region of the high magnetic field, uses very efficient attenuators (tungsten- or tantalum- or stainless-steel-boron carbide mixtures), and is only 1 m thick. The outer blanket/shield is 131 cm and consists of an optimized composition of stainless steel and boron carbide. For the design parameters of 0.2 MW/m 2 neutron wall loading and 50 percent duty cycle, the reactor components can operate satisfactorily up to (a) 10 yr for the stainless-steel first wall, (b) 10 yr for the superconductor composite after which magnet warmup becomes necessary, and (c) 30 yr for the Mylar insulation. Nuclear heat generation rates in the blanket/shield and magnet are well within the practical limits for heat removal
Engineering Parameters in Bioreactor's Design: A Critical Aspect in Tissue Engineering
Amoabediny, Ghassem; Pouran, Behdad; Tabesh, Hadi; Shokrgozar, Mohammad Ali; Haghighipour, Nooshin; Khatibi, Nahid; Mottaghy, Khosrow; Zandieh-Doulabi, Behrouz
2013-01-01
Bioreactors are important inevitable part of any tissue engineering (TE) strategy as they aid the construction of three-dimensional functional tissues. Since the ultimate aim of a bioreactor is to create a biological product, the engineering parameters, for example, internal and external mass transfer, fluid velocity, shear stress, electrical current distribution, and so forth, are worth to be thoroughly investigated. The effects of such engineering parameters on biological cultures have been addressed in only a few preceding studies. Furthermore, it would be highly inefficient to determine the optimal engineering parameters by trial and error method. A solution is provided by emerging modeling and computational tools and by analyzing oxygen, carbon dioxide, and nutrient and metabolism waste material transports, which can simulate and predict the experimental results. Discovering the optimal engineering parameters is crucial not only to reduce the cost and time of experiments, but also to enhance efficacy and functionality of the tissue construct. This review intends to provide an inclusive package of the engineering parameters together with their calculation procedure in addition to the modeling techniques in TE bioreactors. PMID:24000327
Engineering parameters in bioreactor's design: a critical aspect in tissue engineering.
Salehi-Nik, Nasim; Amoabediny, Ghassem; Pouran, Behdad; Tabesh, Hadi; Shokrgozar, Mohammad Ali; Haghighipour, Nooshin; Khatibi, Nahid; Anisi, Fatemeh; Mottaghy, Khosrow; Zandieh-Doulabi, Behrouz
2013-01-01
Bioreactors are important inevitable part of any tissue engineering (TE) strategy as they aid the construction of three-dimensional functional tissues. Since the ultimate aim of a bioreactor is to create a biological product, the engineering parameters, for example, internal and external mass transfer, fluid velocity, shear stress, electrical current distribution, and so forth, are worth to be thoroughly investigated. The effects of such engineering parameters on biological cultures have been addressed in only a few preceding studies. Furthermore, it would be highly inefficient to determine the optimal engineering parameters by trial and error method. A solution is provided by emerging modeling and computational tools and by analyzing oxygen, carbon dioxide, and nutrient and metabolism waste material transports, which can simulate and predict the experimental results. Discovering the optimal engineering parameters is crucial not only to reduce the cost and time of experiments, but also to enhance efficacy and functionality of the tissue construct. This review intends to provide an inclusive package of the engineering parameters together with their calculation procedure in addition to the modeling techniques in TE bioreactors.
Directory of Open Access Journals (Sweden)
Lionel Ripoll
2016-11-01
Full Text Available Vitamin C is widely use in cosmetics and pharmaceutics products for its active properties. However ascorbic acid shows unfavourable chemical instability such as oxidation leading to formulation problems. Therefore, carriers, such as micro- and nanoparticles, have been widely investigated as delivery systems for vitamin C to improve its beneficial effects in skin treatment. However, none of the previous studies have been able to produce microparticles with a high encapsulation entrapment of vitamin C. The aim of the present study is to use an experimental design to optimize the synthesis of polyamide microparticles for the delivery of ascorbic acid. The effect of four formulation parameters on microparticles properties (size and morphology, encapsulation efficiency and yield, release kinetics were investigated using a surface response design. Finally, we were able to obtain stable microparticles containing more than 65% of vitamin C. This result confirms the effectiveness of using design of experiments for the optimisation of microparticle formulation and supports the proposal of using them as candidate for the delivery of vitamin C in skin treatment.
Experimental evaluation of a quasi-modal parameter based rotor foundation identification technique
Yu, Minli; Liu, Jike; Feng, Ningsheng; Hahn, Eric J.
2017-12-01
Correct modelling of the foundation of rotating machinery is an invaluable asset in model-based rotor dynamic study. One attractive approach for such purpose is to identify the relevant modal parameters of an equivalent foundation using the motion measurements of rotor and foundation at the bearing supports. Previous research showed that, a complex quasi-modal parameter based system identification technique could be feasible for this purpose; however, the technique was only validated by identifying simple structures under harmonic excitation. In this paper, such identification technique is further extended and evaluated by identifying the foundation of a numerical rotor-bearing-foundation system and an experimental rotor rig respectively. In the identification of rotor foundation with multiple bearing supports, all application points of excitation forces transmitted through bearings need to be included; however the assumed vibration modes far outside the rotor operating speed cannot or not necessary to be identified. The extended identification technique allows one to identify correctly an equivalent foundation with fewer modes than the assumed number of degrees of freedom, essentially by generalising the technique to be able to handle rectangular complex modal matrices. The extended technique is robust in numerical and experimental validation and is therefore likely to be applicable in the field.
Intuitive web-based experimental design for high-throughput biomedical data.
Friedrich, Andreas; Kenar, Erhan; Kohlbacher, Oliver; Nahnsen, Sven
2015-01-01
Big data bioinformatics aims at drawing biological conclusions from huge and complex biological datasets. Added value from the analysis of big data, however, is only possible if the data is accompanied by accurate metadata annotation. Particularly in high-throughput experiments intelligent approaches are needed to keep track of the experimental design, including the conditions that are studied as well as information that might be interesting for failure analysis or further experiments in the future. In addition to the management of this information, means for an integrated design and interfaces for structured data annotation are urgently needed by researchers. Here, we propose a factor-based experimental design approach that enables scientists to easily create large-scale experiments with the help of a web-based system. We present a novel implementation of a web-based interface allowing the collection of arbitrary metadata. To exchange and edit information we provide a spreadsheet-based, humanly readable format. Subsequently, sample sheets with identifiers and metainformation for data generation facilities can be created. Data files created after measurement of the samples can be uploaded to a datastore, where they are automatically linked to the previously created experimental design model.
Charges collection induced in APS by heavy particles: influence of design parameters
International Nuclear Information System (INIS)
Belredon, Xavier
2003-01-01
We have studied the design parameters influence on heavy ions-induced charge collection physics in APS. The goal is to determine the key parameters for an optimised space environment 'particle detector' APS design. It appears that diffusion is the dominant charge collection mechanism in all the studied technology types, with a smaller magnitude in case of epitaxial technologies. Following proton irradiation, a delayed charge collection and loss of collected charges have been observed. These phenomena are explained by the combination of carriers diffusion and action of the traps generated in the device. Even if they cannot be avoid in space applications, these effects are reduced in case of epitaxial technologies. This work led to the design parameters definition of an optimized APS 'particle detector' and to its fabrication. The results obtained on this APS confirm the previous conclusions and let us define the detection range of such detectors from 0.03 to 50 MeV.cm 2 .mg -1 . (author) [fr
Directory of Open Access Journals (Sweden)
R. Biggs
2003-12-01
Full Text Available The experimental burn plot (EBP trial initiated in 1954 is one of few ongoing long-termfire ecology research projects in Africa. The trial aims to assess the impacts of differentfire regimes in the Kruger National Park. Recent studies on the EBPs have raised questions as to the experimental design of the trial, and the appropriate model specificationwhen analysing data. Archival documentation reveals that the original design was modified on several occasions, related to changes in the park's fire policy. These modifications include the addition of extra plots, subdivision of plots and changes in treatmentsover time, and have resulted in a design which is only partially randomised. The representativity of the trial plots has been questioned on account of their relatively small size,the concentration of herbivores on especially the frequently burnt plots, and soil variation between plots. It is suggested that these factors be included as covariates inexplanatory models or that certain plots be excluded from data analysis based on resultsof independent studies of these factors. Suggestions are provided for the specificationof the experimental design when analysing data using Analysis of Variance. It is concluded that there is no practical alternative to treating the trial as a fully randomisedcomplete block design.
Design study of the experimental multi-purpose high temperature gas-cooled reactor
International Nuclear Information System (INIS)
Tsunoda, Ryokichi
1981-01-01
In this paper, the design study carried out since 1973 is outlined. The basic conceptual design was performed in fiscal 1973. In this design, concept was established on the total system of the experimental high temperature gas-cooled reactor including heat-utilizing system. The first conceptual design was carried out in fiscal 1974. The range of design was limited to the experimental reactor and its direct heat-removing system. The part 2 of the first conceptual design was performed in fiscal 1975, and the system design concerning the plant characteristics was made. The part 1 of the adjustment design was carried out in fiscal 1976, and the subject was the adjustment design of plant systems. The part 2 was performed in fiscal 1977, and the characteristics of plant control system were analyzed. In fiscal 1978, the analysis of flow characteristics in the core was made. The integrated system design was carried out in fiscal 1979, and the design of the total plant system except heat-utilizing system was started again. The part 1 of the detailed design was performed in fiscal 1980, and in addition, the possibility of increasing power output was examined. The construction cost of the experimental reactor plant estimated in 1979 was far higher than that in 1973. (Kako, I.)
International Nuclear Information System (INIS)
1979-03-01
This document contains up-to-date data on existing or firmly decided prototype or demonstration LMFBR reactors (Table I), on planned commercial size LMFBR according to the present status of design (Table II) and on experimental fast reactors such as BOR-60, DFR, EBR-II, FERMI, FFTF, JOYO, KNK-II, PEC, RAPSODIE-FORTISSIMO (Table III). Only corrected and revised parameters submitted by the countries participating in the IWGFR are included in this document
Design of an adaptive pole assignment controller for steam generators and its experimental study
International Nuclear Information System (INIS)
Na, Man Gyun; No, Hee Cheon
1992-01-01
An adaptive observer is designed that both parameters and state variables of the steam generator are estimated simultaneously. A pole assignment controller is derived on the basis of the adaptive observer. The characteristics of the overall closed-loop control system can be expressed in terms of its poles, assigned poles. The troublesome tuning procedure of the P-I controller is reduced to the determination of the desired poles only. The proposed algorithm is compared with the conventional P-I controller through numerical simulation. Also, the adaptive pole assignment controller is studied experimentally by implementing it to the mock-up of the nuclear steam generator. The adaptive pole assignment controller shows better responses than the P-l controller does. (Author)
Verification of kinetic parameters of coupled fast-thermal core HERBE
International Nuclear Information System (INIS)
Pesic, M.; Marinkovic, P.; Milosevic, M.; Nikolic, D.; Zavaljevski, N.; Milovanovic, S.; Ljubenov, V.
1997-03-01
The HERBE system is a new coupled fast-thermal core constructed in 1989 at the RB critical heavy water assembly at the VINCA Institute. It was designed with the aim to improve experimental possibilities in fast neutron fields and for experimental verification of reactor design-oriented methods. This paper overviews experiments for kinetic parameters verification carried out at HERBE system. Their short description and comparison of experimental and calculation results are included. A brief introduction to the computer codes used in the calculations is presented too. (author)
Experimental parameter study for passive vortex generators on a 30% thick airfoil
Baldacchino, D.; Simao Ferreira, C.; De Tavernier, D.A.M.; Timmer, W.A.; van Bussel, G.J.W.
2018-01-01
Passive vane-type vortex generators (VGs) are commonly used on wind turbine blades to mitigate the effects of flow separation. However, significant uncertainty surrounds VG design guidelines. Understanding the influence of VG parameters on airfoil performance requires a systematic approach
Modelled basic parameters for semi-industrial irradiation plant design
International Nuclear Information System (INIS)
Mangussi, J.
2009-01-01
The basic parameters of an irradiation plant design are the total activity, the product uniformity ratio and the efficiency process. The target density, the minimum dose required and the throughput depends on the use to which the irradiator will be put at. In this work, a model for calculating the specific dose rate at several depths in an infinite homogeneous medium produced by a slab source irradiator is presented. The product minimum dose rate for a set of target thickness is obtained. The design method steps are detailed and an illustrative example is presented. (author)
Study of Formulation Variables Influencing Polymeric Microparticles by Experimental Design
Directory of Open Access Journals (Sweden)
Jitendra B. Naik
2014-04-01
Full Text Available The objective of this study was to prepare diclofenac sodium loaded microparticles by single emulsion [oil-in-water (o/w] solvent evaporation method. The 22 experimental design methodology was used to evaluate the effect of two formulation variables on microspheres properties using the Design-Expert® software and evaluated for their particle size, morphology, and encapsulation efficiency and in vitro drug release. The graphical and mathematical analysis of the design showed that the independent variables were a significant effect on the encapsulation efficiency and drug release of microparticles. The low magnitudes of error and significant values of R2 prove the high prognostic ability of the design. The microspheres showed high encapsulation efficiency with an increase in the amount of polymer and decrease in the amount of PVA in the formulation. The particles were found to be spherical with smooth surface. Prolonged drug release and enhancement of encapsulation efficiency of polymeric microparticles can be successfully obtained with an application of experimental design technique.
Experimental Design for Hanford Low-Activity Waste Glasses with High Waste Loading
Energy Technology Data Exchange (ETDEWEB)
Piepel, Gregory F. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Cooley, Scott K. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Vienna, John D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Crum, Jarrod V. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
2015-07-24
This report discusses the development of an experimental design for the initial phase of the Hanford low-activity waste (LAW) enhanced glass study. This report is based on a manuscript written for an applied statistics journal. Appendices A, B, and E include additional information relevant to the LAW enhanced glass experimental design that is not included in the journal manuscript. The glass composition experimental region is defined by single-component constraints (SCCs), linear multiple-component constraints (MCCs), and a nonlinear MCC involving 15 LAW glass components. Traditional methods and software for designing constrained mixture experiments with SCCs and linear MCCs are not directly applicable because of the nonlinear MCC. A modification of existing methodology to account for the nonlinear MCC was developed and is described in this report. One of the glass components, SO_{3}, has a solubility limit in glass that depends on the composition of the balance of the glass. A goal was to design the experiment so that SO_{3} would not exceed its predicted solubility limit for any of the experimental glasses. The SO_{3} solubility limit had previously been modeled by a partial quadratic mixture model expressed in the relative proportions of the 14 other components. The partial quadratic mixture model was used to construct a nonlinear MCC in terms of all 15 components. In addition, there were SCCs and linear MCCs. This report describes how a layered design was generated to (i) account for the SCCs, linear MCCs, and nonlinear MCC and (ii) meet the goals of the study. A layered design consists of points on an outer layer, and inner layer, and a center point. There were 18 outer-layer glasses chosen using optimal experimental design software to augment 147 existing glass compositions that were within the LAW glass composition experimental region. Then 13 inner-layer glasses were chosen with the software to augment the existing and outer
Design optimization of structural parameters in double gate MOSFETs for RF applications
International Nuclear Information System (INIS)
Liang Jiale; Xiao Han; Huang Ru; Wang Pengfei; Wang Yangyuan
2008-01-01
Double gate (DG) MOSFETs have recently attracted much attention for both logic and analog/RF applications. In this paper we focus on the design consideration of DG devices for RF applications. The different influences of key structural parameters on RF characteristics are comprehensively studied and optimized, including body thickness, spacer length and source/drain raised height. The impact of the fluctuation of geometrical parameters of DG devices on RF figures-of-merit are estimated. In addition, different dominance of structural parameters for RF applications is studied in DG devices with different channel lengths. The dependence of RF performance on the gate length downscaling of DG devices is also discussed. The obtained results give the design guidelines for DG devices for RF applications
Statistical experimental design for saltstone mixtures
International Nuclear Information System (INIS)
Harris, S.P.; Postles, R.L.
1992-01-01
The authors used a mixture experimental design for determining a window of operability for a process at the U.S. Department of Energy, Savannah River Site, Defense Waste Processing Facility (DWPF). The high-level radioactive waste at the Savannah River Site is stored in large underground carbon steel tanks. The waste consists of a supernate layer and a sludge layer. Cesium-137 will be removed from the supernate by precipitation and filtration. After further processing, the supernate layer will be fixed as a grout for disposal in concrete vaults. The remaining precipitate will be processed at the DWPF with treated waste tank sludge and glass-making chemicals into borosilicate glass. The leach-rate properties of the supernate grout formed from various mixes of solidified coefficients for NO 3 and chromium were used as a measure of leach rate. Various mixes of cement, Ca(OH) 2 , salt, slag, and fly ash were used. These constituents comprise the whole mix. Thus, a mixture experimental design was used. The regression procedure (PROC REG) in SAS was used to produce analysis of variance (ANOVA) statistics. In addition, detailed model diagnostics are readily available for identifying suspicious observations. For convenience, trillinear contour (TLC) plots, a standard graphics tool for examining mixture response surfaces, of the fitted model were produced using ECHIP
International Nuclear Information System (INIS)
Amendola, A.; Astolfi, M.; Lisanti, B.
1983-01-01
The report describes the how-to-use of the codes: MUP (Monte Carlo Uncertainty Propagation) for uncertainty analysis by Monte Carlo simulation, including correlation analysis, extreme value identification and study of selected ranges of the variable space; CEC-DES (Central Composite Design) for building experimental matrices according to the requirements of Central Composite and Factorial Experimental Designs; and, STRADE (Stratified Random Design) for experimental designs based on the Latin Hypercube Sampling Techniques. Application fields, of the codes are probabilistic risk assessment, experimental design, sensitivity analysis and system identification problems
Conceptual design of fusion experimental reactor (FER)
International Nuclear Information System (INIS)
1985-01-01
The Fusion Experimental Reactor (FER) being developed at JAERI as a next generation tokamak to JT-60 has a major mission of realizing a self-ignited long-burning DT plasma and demonstrating engineering feasibility. During FY82 and FY83 a comprehensive and intensive conceptual design study has been conducted for a pulsed operation FER as a reference option which employs a conventional inductive current drive and a double-null divertor. In parallel with the reference design, studies have been carried out to evaluate advanced reactor concepts such as quasi-steady state operation and steady state operation based on RF current drive and pumped limiter, and comparative studies for single-null divertor/pumped limiter. This report presents major results obtained primarily from FY83 design studies, while the results of FY82 design studies are described in previous references (JAERI-M 83-213--216). (author)
Krishnan, Thulasirajan; Purushothaman, Revathi
2017-07-01
There are several parameters that influence the properties of geopolymer concrete, which contains recycled concrete aggregate as the coarse aggregate. In the present study, the vital parameters affecting the compressive strength of geopolymer concrete containing recycled concrete aggregate are analyzedby varying four parameters with two levels using full factorial design in statistical software Minitab® 17. The objective of the present work is to gain an idea on the optimization, main parameter effects, their interactions and the predicted response of the model generated using factorial design. The parameters such as molarity of sodium hydroxide (8M and 12M), curing time (6hrs and 24 hrs), curing temperature (60°C and 90°C) and percentage of recycled concrete aggregate (0% and 100%) are considered. The results show that the curing time, molarity of sodium hydroxide and curing temperature were the orderly significant parameters and the percentage of Recycled concrete aggregate (RCA) was statistically insignificant in the production of geopolymer concrete. Thus, it may be noticeable that the RCA content had negligible effect on the compressive strength of geopolymer concrete. The expected responses from the generated model showed a satisfactory and rational agreement to the experimental data with the R2 value of 97.70%. Thus, geopolymer concrete comprising recycled concrete aggregate can solve the major social and environmental concerns such as the depletion of the naturally available aggregate sources and disposal of construction and demolition waste into the landfill.
Directory of Open Access Journals (Sweden)
Abd Elaziz Sarrai
2016-05-01
Full Text Available The feasibility of the application of the Photo-Fenton process in the treatment of aqueous solution contaminated by Tylosin antibiotic was evaluated. The Response Surface Methodology (RSM based on Central Composite Design (CCD was used to evaluate and optimize the effect of hydrogen peroxide, ferrous ion concentration and initial pH as independent variables on the total organic carbon (TOC removal as the response function. The interaction effects and optimal parameters were obtained by using MODDE software. The significance of the independent variables and their interactions was tested by means of analysis of variance (ANOVA with a 95% confidence level. Results show that the concentration of the ferrous ion and pH were the main parameters affecting TOC removal, while peroxide concentration had a slight effect on the reaction. The optimum operating conditions to achieve maximum TOC removal were determined. The model prediction for maximum TOC removal was compared to the experimental result at optimal operating conditions. A good agreement between the model prediction and experimental results confirms the soundness of the developed model.
Experimental Design: Utilizing Microsoft Mathematics in Teaching and Learning Calculus
Oktaviyanthi, Rina; Supriani, Yani
2015-01-01
The experimental design was conducted to investigate the use of Microsoft Mathematics, free software made by Microsoft Corporation, in teaching and learning Calculus. This paper reports results from experimental study details on implementation of Microsoft Mathematics in Calculus, students' achievement and the effects of the use of Microsoft…
Methods for the neutronic design of a Supersara experimental loop
International Nuclear Information System (INIS)
Casali, F.; Cepraga, D.
1982-01-01
This paper describes a method for the neutronic design of experimental loops irradiated in D 2 O experimental reactors, like Essor. The calculation approach concerns the definition of a Weigner-Seitz cell where the loop under examination be subjected to the same neutronic conditions as in the actual reactor
Optimum design of forging process parameters and preform shape under uncertainties
International Nuclear Information System (INIS)
Repalle, Jalaja; Grandhi, Ramana V.
2004-01-01
Forging is a highly complex non-linear process that is vulnerable to various uncertainties, such as variations in billet geometry, die temperature, material properties, workpiece and forging equipment positional errors and process parameters. A combination of these uncertainties could induce heavy manufacturing losses through premature die failure, final part geometric distortion and production risk. Identifying the sources of uncertainties, quantifying and controlling them will reduce risk in the manufacturing environment, which will minimize the overall cost of production. In this paper, various uncertainties that affect forging tool life and preform design are identified, and their cumulative effect on the forging process is evaluated. Since the forging process simulation is computationally intensive, the response surface approach is used to reduce time by establishing a relationship between the system performance and the critical process design parameters. Variability in system performance due to randomness in the parameters is computed by applying Monte Carlo Simulations (MCS) on generated Response Surface Models (RSM). Finally, a Robust Methodology is developed to optimize forging process parameters and preform shape. The developed method is demonstrated by applying it to an axisymmetric H-cross section disk forging to improve the product quality and robustness
International Nuclear Information System (INIS)
Lange, Kyle J.; Anderson, W. Kyle
2010-01-01
The problem of applying sensitivity analysis to a one-dimensional atmospheric radio frequency plasma discharge simulation is considered. A fluid simulation is used to model an atmospheric pressure radio frequency helium discharge with a small nitrogen impurity. Sensitivity derivatives are computed for the peak electron density with respect to physical inputs to the simulation. These derivatives are verified using several different methods to compute sensitivity derivatives. It is then demonstrated how sensitivity derivatives can be used within a design cycle to change these physical inputs so as to increase the peak electron density. It is also shown how sensitivity analysis can be used in conjunction with experimental data to obtain better estimates for rate and transport parameters. Finally, it is described how sensitivity analysis could be used to compute an upper bound on the uncertainty for results from a simulation.
A Study on Criticality Safety Parameters of New Fuel Storage Rack Design
International Nuclear Information System (INIS)
Ahn, Joon Gi; Kim, Hyeong Heon
2012-01-01
The dry new fuel storage rack shall maintain the subcritical condition (i.e., k-eff < 0.95) when fully flooded with water and the k-eff will not exceed 0.98 even assuming that the optimum moderation causes the highest reactivity. Thus, the design parameters of the new fuel rack are determined optimally by considering both the full density water flooding condition and the optimum moderation condition. The behavior of the keff as the variation of design parameter of the new fuel rack was investigated as the function of the moderating water density
A Study on Criticality Safety Parameters of New Fuel Storage Rack Design
Energy Technology Data Exchange (ETDEWEB)
Ahn, Joon Gi; Kim, Hyeong Heon [KEPCO E and C, Daejeon (Korea, Republic of)
2012-05-15
The dry new fuel storage rack shall maintain the subcritical condition (i.e., k-eff < 0.95) when fully flooded with water and the k-eff will not exceed 0.98 even assuming that the optimum moderation causes the highest reactivity. Thus, the design parameters of the new fuel rack are determined optimally by considering both the full density water flooding condition and the optimum moderation condition. The behavior of the keff as the variation of design parameter of the new fuel rack was investigated as the function of the moderating water density
International Nuclear Information System (INIS)
Lee, Seung Min
2009-01-01
This work presents a theoretical study of reactor kinetics focusing on the methodology of calculation and the experimental measurements of the so-called kinetic parameters. A comparison between the methodology based on the Dulla's formalism and the classical method is made. The objective is to exhibit the dependence of the parameters on subcriticality level and perturbation. Two different slab type systems were considered: thermal one and fast one, both with homogeneous media. One group diffusion model was used for the fast reactor, and for the thermal system, two groups diffusion model, considering, in both case, only one precursor's family. The solutions were obtained using the expansion method. Also, descriptions of the main experimental methods of measurements of the kinetic parameters are presented in order to put a question about the compatibility of these methods in subcritical region. (author)
Directory of Open Access Journals (Sweden)
Changbao CHU
2014-04-01
Full Text Available In this paper, H type brake by wire system based on giant-magnetostrictive material is designed from two aspects of hardware and software. System principle prototype is manufactured. Hardware circuit mainly includes the Sepic circuit, current detection circuit, over current protection circuit, PWM driver protection circuit. Circuit parameters can be obtained through by theoretical calculation. Pedal sensor signal is taken as main control variable, look-up table method is used for brake by wire system. The experimental results show that the system can meet the braking requirements. It proves the feasibility of the scheme.
Dasgupta, Annwesa P; Anderson, Trevor R; Pelaez, Nancy
2014-01-01
It is essential to teach students about experimental design, as this facilitates their deeper understanding of how most biological knowledge was generated and gives them tools to perform their own investigations. Despite the importance of this area, surprisingly little is known about what students actually learn from designing biological experiments. In this paper, we describe a rubric for experimental design (RED) that can be used to measure knowledge of and diagnose difficulties with experimental design. The development and validation of the RED was informed by a literature review and empirical analysis of undergraduate biology students' responses to three published assessments. Five areas of difficulty with experimental design were identified: the variable properties of an experimental subject; the manipulated variables; measurement of outcomes; accounting for variability; and the scope of inference appropriate for experimental findings. Our findings revealed that some difficulties, documented some 50 yr ago, still exist among our undergraduate students, while others remain poorly investigated. The RED shows great promise for diagnosing students' experimental design knowledge in lecture settings, laboratory courses, research internships, and course-based undergraduate research experiences. It also shows potential for guiding the development and selection of assessment and instructional activities that foster experimental design. © 2014 A. P. Dasgupta et al. CBE—Life Sciences Education © 2014 The American Society for Cell Biology. This article is distributed by The American Society for Cell Biology under license from the author(s). It is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).
Investigating dynamic parameters in HWZPR ased on the experimental and calculated results
Energy Technology Data Exchange (ETDEWEB)
Nasrazadani, Zahra; Behfamia, Manochehar; Khosandi, Jamshid; Mirvakili, Mohammad [Reactors Research School, Nuclear Science And Technology Research Institute, Atomic Energy Organization of Iran, Esfahan (Iran, Islamic Republic of)
2016-10-15
The neutron decay constant, α, and effective delayed neutron fraction, β{sub eff}, are important parameters for the control of the dynamic behavior of nuclear reactors. For the heavy water zero power reactor (HWZPR), this document describes the measurements of the neutron decay constant by noise analysis methods, including variance to mean (VTM) ratio and endogenous pulse source (EPS) methods. The measured α is successively used to determine the experimental value of the effective delayed neutron fraction as well. According to the experimental results, β{sub eff} of the HWZPR reactor under study is equal to 7.84e-3. This value is finally used to validate the calculation of the effective delayed neutron fraction by the Monte Carlo methods that are discussed in the document. Using the Monte Carlo N-Particle (MCNP)-4C code, a β{sub eff} value of 7.58e-3 was obtained for the reactor under study. Thus, the relative difference between the β{sub eff} values determined experimentally and by Monte Carlo methods was estimated to be < 4%.
Conceptual design of fusion experimental reactor (FER)
International Nuclear Information System (INIS)
1984-01-01
Conceptual Design of Fusion Experimental Reactor (FER) of which the objective will be to realize self-ignition with D-T reaction is reported. Mechanical Configurations of FER are characterized with a noncircular plasma and a double-null divertor. The primary aim of design studies is to demonstrate fissibility of reactor structures as compact and simple as possible with removable torus sectors. The structures of each component such as a first-wall, blanket, shielding, divertor, magnet and so on have been designed. It is also discussed about essential reactor plant system requirements. In addition to the above, a brief concept of a steady-state reactor based on RF current drive is also discussed. The main aim, in this time, is to examine physical studies of a possible RF steady-state reactor. (author)
Design and experimental results of coaxial circuits for gyroklystron amplifiers
International Nuclear Information System (INIS)
Flaherty, M.K.E.; Lawson, W.; Cheng, J.; Calame, J.P.; Hogan, B.; Latham, P.E.; Granatstein, V.L.
1994-01-01
At the University of Maryland high power microwave source development for use in linear accelerator applications continues with the design and testing of coaxial circuits for gyroklystron amplifiers. This presentation will include experimental results from a coaxial gyroklystron that was tested on the current microwave test bed, and designs for second harmonic coaxial circuits for use in the next generation of the gyroklystron program. The authors present test results for a second harmonic coaxial circuit. Similar to previous second harmonic experiments the input cavity resonated at 9.886 GHz and the output frequency was 19.772 GHz. The coaxial insert was positioned in the input cavity and drift region. The inner conductor consisted of a tungsten rod with copper and ceramic cylinders covering its length. Two tungsten rods that bridged the space between the inner and outer conductors supported the whole assembly. The tube produced over 20 MW of output power with 17% efficiency. Beam interception by the tungsten rods resulted in minor damage. Comparisons with previous non-coaxial circuits showed that the coaxial configuration increased the parameter space over which stable operation was possible. Future experiments will feature an upgraded modulator and beam formation system capable of producing 300 MW of beam power. The fundamental frequency of operation is 8.568 GHz. A second harmonic coaxial gyroklystron circuit was designed for use in the new system. A scattering matrix code predicts a resonant frequency of 17.136 GHz and Q of 260 for the cavity with 95% of the outgoing microwaves in the desired TE032 mode. Efficiency studies of this second harmonic output cavity show 20% expected efficiency. Shorter second harmonic output cavity designs are also being investigated with expected efficiencies near 34%
International Nuclear Information System (INIS)
Sugino, K.; Iwai, T.
2006-01-01
MONJU experimental data analysis was performed by using the detailed calculation scheme for fast reactor cores developed in Japan. Subsequently, feasibility of the MONJU integral data was evaluated by the cross-section adjustment technique for the use of FBR nuclear core design. It is concluded that the MONJU integral data is quite valuable for building up the standard data base for large FBR nuclear core design. In addition, it is found that the application of the updated data base has a possibility to considerably improve the prediction accuracy of neutronic parameters for MONJU. (authors)
Bayesian Optimal Experimental Design Using Multilevel Monte Carlo
Ben Issaid, Chaouki; Long, Quan; Scavino, Marco; Tempone, Raul
2015-01-01
Experimental design is very important since experiments are often resource-exhaustive and time-consuming. We carry out experimental design in the Bayesian framework. To measure the amount of information, which can be extracted from the data in an experiment, we use the expected information gain as the utility function, which specifically is the expected logarithmic ratio between the posterior and prior distributions. Optimizing this utility function enables us to design experiments that yield the most informative data for our purpose. One of the major difficulties in evaluating the expected information gain is that the integral is nested and can be high dimensional. We propose using Multilevel Monte Carlo techniques to accelerate the computation of the nested high dimensional integral. The advantages are twofold. First, the Multilevel Monte Carlo can significantly reduce the cost of the nested integral for a given tolerance, by using an optimal sample distribution among different sample averages of the inner integrals. Second, the Multilevel Monte Carlo method imposes less assumptions, such as the concentration of measures, required by Laplace method. We test our Multilevel Monte Carlo technique using a numerical example on the design of sensor deployment for a Darcy flow problem governed by one dimensional Laplace equation. We also compare the performance of the Multilevel Monte Carlo, Laplace approximation and direct double loop Monte Carlo.
Bayesian Optimal Experimental Design Using Multilevel Monte Carlo
Ben Issaid, Chaouki
2015-01-07
Experimental design is very important since experiments are often resource-exhaustive and time-consuming. We carry out experimental design in the Bayesian framework. To measure the amount of information, which can be extracted from the data in an experiment, we use the expected information gain as the utility function, which specifically is the expected logarithmic ratio between the posterior and prior distributions. Optimizing this utility function enables us to design experiments that yield the most informative data for our purpose. One of the major difficulties in evaluating the expected information gain is that the integral is nested and can be high dimensional. We propose using Multilevel Monte Carlo techniques to accelerate the computation of the nested high dimensional integral. The advantages are twofold. First, the Multilevel Monte Carlo can significantly reduce the cost of the nested integral for a given tolerance, by using an optimal sample distribution among different sample averages of the inner integrals. Second, the Multilevel Monte Carlo method imposes less assumptions, such as the concentration of measures, required by Laplace method. We test our Multilevel Monte Carlo technique using a numerical example on the design of sensor deployment for a Darcy flow problem governed by one dimensional Laplace equation. We also compare the performance of the Multilevel Monte Carlo, Laplace approximation and direct double loop Monte Carlo.
CSIR Research Space (South Africa)
Tshweu, L
2012-10-01
Full Text Available to examine a seven factor system at two levels, as shown in Table 1. Table 1: Taguchi L8 experimental parameters and levels for preparation of PCL-EFV nanoparticles (NPs) Symbol Formulation parameters Levels 1 2 A W1 PVA PBS B Sugar Lactose...
DUINEVELD, C. A. A.; Smilde, A. K.; Doornbos, D. A.
1993-01-01
The construction of a small experimental design for a combination of process and mixture variables is a problem which has not been solved completely by now. In a previous paper we evaluated some designs with theoretical measures. This second paper evaluates the capabilities of the best of these
DUINEVELD, CAA; SMILDE, AK; DOORNBOS, DA
The construction of a small experimental design for a combination of process and mixture variables is a problem which has not been solved completely by now. In a previous paper we evaluated some designs with theoretical measures. This second paper evaluates the capabilities of the best of these
Multi-parameter optimization design of parabolic trough solar receiver
International Nuclear Information System (INIS)
Guo, Jiangfeng; Huai, Xiulan
2016-01-01
Highlights: • The optimal condition can be obtained by multi-parameter optimization. • Exergy and thermal efficiencies are employed as objective function. • Exergy efficiency increases at the expense of heat losses. • The heat obtained by working fluid increases as thermal efficiency grows. - Abstract: The design parameters of parabolic trough solar receiver are interrelated and interact with one another, so the optimal performance of solar receiver cannot be obtained by the convectional single-parameter optimization. To overcome the shortcoming of single-parameter optimization, a multi-parameter optimization of parabolic trough solar receiver is employed based on genetic algorithm in the present work. When the thermal efficiency is taken as the objective function, the heat obtained by working fluid increases while the average temperature of working fluid and wall temperatures of solar receiver decrease. The average temperature of working fluid and the wall temperatures of solar receiver increase while the heat obtained by working fluid decreases generally by taking the exergy efficiency as an objective function. Assuming that the solar radiation intensity remains constant, the exergy obtained by working fluid increases by taking exergy efficiency as the objective function, which comes at the expense of heat losses of solar receiver.
Design parameters for toroidal and bobbin magnetics. [conversion from English to metric units
Mclyman, W. T.
1974-01-01
The adoption by NASA of the metric system for dimensioning to replace long-used English units imposes a requirement on the U.S. transformer designer to convert from the familiar units to the less familiar metric equivalents. Material is presented to assist in that transition in the field of transformer design and fabrication. The conversion data makes it possible for the designer to obtain a fast and close approximation of significant parameters such as size, weight, and temperature rise. Nomographs are included to provide a close approximation for breadboarding purposes. For greater convenience, derivations of some of the parameters are also presented.
International Nuclear Information System (INIS)
Belwanshi, Vinod; Topkar, Anita
2016-01-01
Finite element analysis study has been carried out to optimize the design parameters for bulk micro-machined silicon membranes for piezoresistive pressure sensing applications. The design is targeted for measurement of pressure up to 200 bar for nuclear reactor applications. The mechanical behavior of bulk micro-machined silicon membranes in terms of deflection and stress generation has been simulated. Based on the simulation results, optimization of the membrane design parameters in terms of length, width and thickness has been carried out. Subsequent to optimization of membrane geometrical parameters, the dimensions and location of the high stress concentration region for implantation of piezoresistors have been obtained for sensing of pressure using piezoresistive sensing technique.
Belwanshi, Vinod; Topkar, Anita
2016-05-01
Finite element analysis study has been carried out to optimize the design parameters for bulk micro-machined silicon membranes for piezoresistive pressure sensing applications. The design is targeted for measurement of pressure up to 200 bar for nuclear reactor applications. The mechanical behavior of bulk micro-machined silicon membranes in terms of deflection and stress generation has been simulated. Based on the simulation results, optimization of the membrane design parameters in terms of length, width and thickness has been carried out. Subsequent to optimization of membrane geometrical parameters, the dimensions and location of the high stress concentration region for implantation of piezoresistors have been obtained for sensing of pressure using piezoresistive sensing technique.
The electronic system for mechanical oscillation parameters registration
Directory of Open Access Journals (Sweden)
Bulavin L. A.
2008-08-01
Full Text Available On the basis of the 8-bit microcontroller Microchip PIC16F630 the digital electronic device for harmonic oscillation parameters registration was developed. The device features are simple electric circuit and high operating speed (response time is less than 10 microseconds. The relevant software for the computer-controlled recording of harmonic oscillation parameters was designed. The device can be used as a part of the experimental setup for consistent fluids rheological parameters measurements.
Yang, Jin; Hu, Chuxiong; Zhu, Yu; Wang, Ze; Zhang, Ming
2017-08-01
In this paper, shaping disturbance observer (SDOB) is investigated for precision mechatronic stages with middle-frequency zero/pole type resonance to achieve good motion control performance in practical manufacturing situations. Compared with traditional standard disturbance observer (DOB), in SDOB a pole-zero cancellation based shaping filter is cascaded to the mechatronic stage plant to meet the challenge of motion control performance deterioration caused by actual resonance. Noting that pole-zero cancellation is inevitably imperfect and the controller may even consequently become unstable in practice, frequency domain stability analysis is conducted to find out how each parameter of the shaping filter affects the control stability. Moreover, the robust design criterion of the shaping filter, and the design procedure of SDOB, are both proposed to guide the actual design and facilitate practical implementation. The SDOB with the proposed design criterion is applied to a linear motor driven stage and a voice motor driven stage, respectively. Experimental results consistently validate the effectiveness nature of the proposed SDOB scheme in practical mechatronics motion applications. The proposed SDOB design actually could be an effective unit in the controller design for motion stages of mechanical manufacture equipments.
Razmi, Rasoul; Shahpari, Behrouz; Pourbasheer, Eslam; Boustanifar, Mohammad Hasan; Azari, Zhila; Ebadi, Amin
2016-11-01
A rapid and simple method for the extraction and preconcentration of ceftazidime in aqueous samples has been developed using dispersive liquid-liquid microextraction followed by high-performance liquid chromatography analysis. The extraction parameters, such as the volume of extraction solvent and disperser solvent, salt effect, sample volume, centrifuge rate, centrifuge time, extraction time, and temperature in the dispersive liquid-liquid microextraction process, were studied and optimized with the experimental design methods. Firstly, for the preliminary screening of the parameters the taguchi design was used and then, the fractional factorial design was used for significant factors optimization. At the optimum conditions, the calibration curves for ceftazidime indicated good linearity over the range of 0.001-10 μg/mL with correlation coefficients higher than the 0.98, and the limits of detection were 0.13 and 0.17 ng/mL, for water and urine samples, respectively. The proposed method successfully employed to determine ceftazidime in water and urine samples and good agreement between the experimental data and predictive values has been achieved. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
MYRRHA/XT-ADS primary system design and experimental devices
International Nuclear Information System (INIS)
Maes, D.
2009-01-01
The EUROTRANS project is an integrated project in the Sixth European Framework Program in the context of Partitioning and Transmutation. The objective of this project is to work towards an ETD (European Transmutation Demonstration) in a step-wise manner. The first step is to carry out an advanced design of a small-scale XT-ADS (eXperimental Transmutation in an Accelerator Driven System) for realisation in a short-term (about 10 years) as well as to accomplish a generic conceptual design of EFIT (European Facility for Industrial Transmutation) for realisation in the long-term. The MYRRHA-2005 design served as a starting basis for the XT-ADS. Many options have been revisited and the framework is now set up. While the MYRRHA-2005 design was still a conceptual design, the intention is to get at the end of the EUROTRANS project (March 2009) an advanced design of the XT-ADS, albeit a first advanced design. While the design work performed during the first years of the project (2005-2006) was mainly devoted to optimise and enhance the primary and secondary system configuration according to the suggestions and contributions of our industrial partners (Ansaldo Nucleare, Areva, Suez-Tractebel) within the DM1 (Domain 1 D ESIGN ) , the last year work objectives mainly consisted of (1) the release of the Remote Handling Design Catalogue for XT-ADS and (2) the formulation of the specification of the experimental devices according to the XT-ADS objectives and adapted to the actual XT-ADS core and core support structure design; (3) the detailed calculations of the main XT-ADS primary and secondary system components
Hierarchical adaptive experimental design for Gaussian process emulators
International Nuclear Information System (INIS)
Busby, Daniel
2009-01-01
Large computer simulators have usually complex and nonlinear input output functions. This complicated input output relation can be analyzed by global sensitivity analysis; however, this usually requires massive Monte Carlo simulations. To effectively reduce the number of simulations, statistical techniques such as Gaussian process emulators can be adopted. The accuracy and reliability of these emulators strongly depend on the experimental design where suitable evaluation points are selected. In this paper a new sequential design strategy called hierarchical adaptive design is proposed to obtain an accurate emulator using the least possible number of simulations. The hierarchical design proposed in this paper is tested on various standard analytic functions and on a challenging reservoir forecasting application. Comparisons with standard one-stage designs such as maximin latin hypercube designs show that the hierarchical adaptive design produces a more accurate emulator with the same number of computer experiments. Moreover a stopping criterion is proposed that enables to perform the number of simulations necessary to obtain required approximation accuracy.
Design, construction and testing of a radon experimental chamber
International Nuclear Information System (INIS)
Chavez B, A.; Balcazar G, M.
1991-10-01
To carry out studies on the radon behavior under controlled and stable conditions it was designed and constructed a system that consists of two parts: a container of mineral rich in Uranium and an experimentation chamber with radon united one to the other one by a step valve. The container of uranium mineral approximately contains 800 gr of uranium with a law of 0.28%; the radon gas emanated by the mineral is contained tightly by the container. When the valve opens up the radon gas it spreads to the radon experimental chamber; this contains 3 accesses that allow to install different types of detectors. The versatility of the system is exemplified with two experiments: 1. With the radon experimental chamber and an associated spectroscopic system, the radon and two of its decay products are identified. 2. The design of the system allows to couple the mineral container to other experimental geometries to demonstrate this fact it was coupled and proved a new automatic exchanger system of passive detectors of radon. The results of the new automatic exchanger system when it leave to flow the radon freely among the container and the automatic exchanger through a plastic membrane of 15 m. are shown. (Author)
Efficient Parameter Searches for Colloidal Materials Design with Digital Alchemy
Dodd, Paul, M.; Geng, Yina; van Anders, Greg; Glotzer, Sharon C.
Optimal colloidal materials design is challenging, even for high-throughput or genomic approaches, because the design space provided by modern colloid synthesis techniques can easily have dozens of dimensions. In this talk we present the methodology of an inverse approach we term ''digital alchemy'' to perform rapid searches of design-paramenter spaces with up to 188 dimensions that yield thermodynamically optimal colloid parameters for target crystal structures with up to 20 particles in a unit cell. The method relies only on fundamental principles of statistical mechanics and Metropolis Monte Carlo techniques, and yields particle attribute tolerances via analogues of familiar stress-strain relationships.
Statistical experimental design for refractory coatings
International Nuclear Information System (INIS)
McKinnon, J.A.; Standard, O.C.
2000-01-01
The production of refractory coatings on metal casting moulds is critically dependent on the development of suitable rheological characteristics, such as viscosity and thixotropy, in the initial coating slurry. In this paper, the basic concepts of mixture design and analysis are applied to the formulation of a refractory coating, with illustration by a worked example. Experimental data of coating viscosity versus composition are fitted to a statistical model to obtain a reliable method of predicting the optimal formulation of the coating. Copyright (2000) The Australian Ceramic Society
Panda, Shasanka Shekhar; Bajpai, Minu; Mallick, Saumyaranjan; Sharma, Mehar C
2014-01-01
The objective of the following study is to determine and to compare the different morphological parameters with duration of obstruction created experimentally in unilateral upper ureters of rats. Unilateral upper ureteric obstruction was created in 60 adult Wistar rats that were reversed after predetermined intervals. Rats were sacrificed and ipsilateral kidneys were subjected for analysis of morphological parameters such as renal height, cranio-caudal diameter, antero-posterior diameter, lateral diameter, volume of the pelvis and average cortical thickness: Renal height. Renal height and cranio-caudal diameter of renal pelvis after ipsilateral upper ureteric obstruction started rising as early as 7 days of creating obstruction and were affected earlier than antero-posterior and lateral diameter and also were reversed earlier than other parameters after reversal of obstruction. Renal cortical thickness and volume of the pelvis were affected after prolonged obstruction (> 3 weeks) and were the late parameters to be reversed after reversal of obstruction. Cranio-caudal diameter and renal height were the early morphological parameters to be affected and reversed after reversal of obstruction in experimentally created ipsilateral upper ureteric obstruction.
Optimal Input Design for Aircraft Parameter Estimation using Dynamic Programming Principles
Morelli, Eugene A.; Klein, Vladislav
1990-01-01
A new technique was developed for designing optimal flight test inputs for aircraft parameter estimation experiments. The principles of dynamic programming were used for the design in the time domain. This approach made it possible to include realistic practical constraints on the input and output variables. A description of the new approach is presented, followed by an example for a multiple input linear model describing the lateral dynamics of a fighter aircraft. The optimal input designs produced by the new technique demonstrated improved quality and expanded capability relative to the conventional multiple input design method.
Energy Technology Data Exchange (ETDEWEB)
Katata, Lebogang, E-mail: lebzakate@yahoo.com; Tshweu, Lesego; Naidoo, Saloshnee; Kalombo, Lonji; Swai, Hulda [Materials Science and Manufacturing, Centre of Polymers and Composites, Council for Scientific and Industrial Research (South Africa)
2012-11-15
Efavirenz (EFV) is one of the first-line antiretroviral drugs recommended by the World Health Organisation for treating HIV. It is a hydrophobic drug that suffers from low aqueous solubility (4 {mu}g/mL), which leads to a limited oral absorption and low bioavailability. In order to improve its oral bioavailability, nano-sized polymeric delivery systems are suggested. Spray dried polycaprolactone-efavirenz (PCL-EFV) nanoparticles were prepared by the double emulsion method. The Taguchi method, a statistical design with an L{sub 8} orthogonal array, was implemented to optimise the formulation parameters of PCL-EFV nanoparticles. The types of sugar (lactose or trehalose), surfactant concentration and solvent (dichloromethane and ethyl acetate) were chosen as significant parameters affecting the particle size and polydispersity index (PDI). Small nanoparticles with an average particle size of less than 254 {+-} 0.95 nm in the case of ethyl acetate as organic solvent were obtained as compared to more than 360 {+-} 19.96 nm for dichloromethane. In this study, the type of solvent and sugar were the most influencing parameters of the particle size and PDI. Taguchi method proved to be a quick, valuable tool in optimising the particle size and PDI of PCL-EFV nanoparticles. The optimised experimental values for the nanoparticle size and PDI were 217 {+-} 2.48 nm and 0.093 {+-} 0.02.
International Nuclear Information System (INIS)
Katata, Lebogang; Tshweu, Lesego; Naidoo, Saloshnee; Kalombo, Lonji; Swai, Hulda
2012-01-01
Efavirenz (EFV) is one of the first-line antiretroviral drugs recommended by the World Health Organisation for treating HIV. It is a hydrophobic drug that suffers from low aqueous solubility (4 μg/mL), which leads to a limited oral absorption and low bioavailability. In order to improve its oral bioavailability, nano-sized polymeric delivery systems are suggested. Spray dried polycaprolactone-efavirenz (PCL-EFV) nanoparticles were prepared by the double emulsion method. The Taguchi method, a statistical design with an L 8 orthogonal array, was implemented to optimise the formulation parameters of PCL-EFV nanoparticles. The types of sugar (lactose or trehalose), surfactant concentration and solvent (dichloromethane and ethyl acetate) were chosen as significant parameters affecting the particle size and polydispersity index (PDI). Small nanoparticles with an average particle size of less than 254 ± 0.95 nm in the case of ethyl acetate as organic solvent were obtained as compared to more than 360 ± 19.96 nm for dichloromethane. In this study, the type of solvent and sugar were the most influencing parameters of the particle size and PDI. Taguchi method proved to be a quick, valuable tool in optimising the particle size and PDI of PCL-EFV nanoparticles. The optimised experimental values for the nanoparticle size and PDI were 217 ± 2.48 nm and 0.093 ± 0.02.
Machine Learning and Experimental Design for Hydrogen Cosmology
Rapetti, David; Tauscher, Keith A.; Burns, Jack O.; Mirocha, Jordan; Switzer, Eric; Monsalve, Raul A.; Furlanetto, Steven R.; Bowman, Judd D.
2018-06-01
Based on two powerful innovations, we present a new pipeline to analyze the redshifted sky-averaged 21-cm spectrum (~10-200 MHz) of neutral hydrogen from the first stars, galaxies and black holes. First, we combine machine learning and model selection techniques to extract the global 21-cm signal from foreground and instrumental systematics. Second, we employ experimental designs to increase our ability to separate these two components in data sets. For measurements with foreground polarization induced by rotation about the anisotropic low-frequency radio sky on a large beam, we incorporate this information into the likelihood to distinguish the unpolarized 21-cm signal from the rest of the data. For experiments with a drift scan strategy, we take advantage of the varying foreground in time to identify the constant 21-cm signal. This pipeline can be applied to either lunar orbit/surface instruments shielded from terrestrial and solar radio contamination, or existing ground-based observations, such as those from the EDGES collaboration that recently observed an absorption trough potentially consistent with the global 21-cm signal of Cosmic Dawn. Finally, this pipeline allows us to constrain physical parameters for a given model of the first luminous objects plus exotic physics in the early universe, from e.g. dark matter, through an MCMC analysis that uses the extracted signal as a starting point, providing key efficiency for unexplored cosmologies.
Simultaneous estimation of experimental and material parameters
CSIR Research Space (South Africa)
Jansen van Rensburg, GJ
2012-07-01
Full Text Available to the experimental data. An inverse analysis is performed that determines material properties and boundary conditions simultaneously. This idea is investigated using virtual experimental data. The virtual experimental data is obtained by performing a finite element...
Optimizing laboratory animal stress paradigms: The H-H* experimental design.
McCarty, Richard
2017-01-01
Major advances in behavioral neuroscience have been facilitated by the development of consistent and highly reproducible experimental paradigms that have been widely adopted. In contrast, many different experimental approaches have been employed to expose laboratory mice and rats to acute versus chronic intermittent stress. An argument is advanced in this review that more consistent approaches to the design of chronic intermittent stress experiments would provide greater reproducibility of results across laboratories and greater reliability relating to various neural, endocrine, immune, genetic, and behavioral adaptations. As an example, the H-H* experimental design incorporates control, homotypic (H), and heterotypic (H*) groups and allows for comparisons across groups, where each animal is exposed to the same stressor, but that stressor has vastly different biological and behavioral effects depending upon each animal's prior stress history. Implementation of the H-H* experimental paradigm makes possible a delineation of transcriptional changes and neural, endocrine, and immune pathways that are activated in precisely defined stressor contexts. Copyright Â© 2016 Elsevier Ltd. All rights reserved.
SCRAED - Simple and Complex Random Assignment in Experimental Designs
Alferes, Valentim R.
2009-01-01
SCRAED is a package of 37 self-contained SPSS syntax files that performs simple and complex random assignment in experimental designs. For between-subjects designs, SCRAED includes simple random assignment (no restrictions, forced equal sizes, forced unequal sizes, and unequal probabilities), block random assignment (simple and generalized blocks), and stratified random assignment (no restrictions, forced equal sizes, forced unequal sizes, and unequal probabilities). For within-subject...
Parameters Design for a Parallel Hybrid Electric Bus Using Regenerative Brake Model
Directory of Open Access Journals (Sweden)
Zilin Ma
2014-01-01
Full Text Available A design methodology which uses the regenerative brake model is introduced to determine the major system parameters of a parallel electric hybrid bus drive train. Hybrid system parameters mainly include the power rating of internal combustion engine (ICE, gear ratios of transmission, power rating, and maximal torque of motor, power, and capacity of battery. The regenerative model is built in the vehicle model to estimate the regenerative energy in the real road conditions. The design target is to ensure that the vehicle meets the specified vehicle performance, such as speed and acceleration, and at the same time, operates the ICE within an expected speed range. Several pairs of parameters are selected from the result analysis, and the fuel saving result in the road test shows that a 25% reduction is achieved in fuel consumption.
The influence of selected design and operating parameters on the dynamics of the steam micro-turbine
Żywica, Grzegorz; Kiciński, Jan
2015-10-01
The topic of the article is the analysis of the influence of selected design parameters and operating conditions on the radial steam micro-turbine, which was adapted to operate with low-boiling agent in the Organic Rankine Cycle (ORC). In the following parts of this article the results of the thermal load analysis, the residual unbalance and the stiffness of bearing supports are discussed. Advanced computational methods and numerical models have been used. Computational analysis showed that the steam micro-turbine is characterized by very good dynamic properties and is resistant to extreme operating conditions. The prototype of micro-turbine has passed a series of test calculations. It has been found that it can be subjected to experimental research in the micro combined heat and power system.
Energy Technology Data Exchange (ETDEWEB)
Hellmann, S; Funke, F; Greger, G U; Bleier, A; Morell, W [Siemens AG, Power Generation Group, Erlangen (Germany)
1996-12-01
An extensive experimental parameter study was performed on the deposition and on the resuspension kinetics in the reaction system iodine/organically coated surfaces. Both reactions in the gas phase and in the liquid phase were investigated and kinetic rate constants suitable for modelling were derived. Previous experimental studies on the reaction of iodine with organic coated surfaces were mostly limited to temperatures below 100{sup o}C. Thus, this parameter study aims at filling a gap and providing kinetic data on heterogeneous reactions with organic surfaces in the accident-relevant temperature range of 100-160{sup o}C. Two types of laboratory experiments carried out at Siemens/KWU using coatings representative for German power plants (epoxy-tape paint), namely gas phase tests and liquid phase tests. (author) 6 figs., 6 tabs., 5 refs.
Randomizing Roaches: Exploring the "Bugs" of Randomization in Experimental Design
Wagler, Amy; Wagler, Ron
2014-01-01
Understanding the roles of random selection and random assignment in experimental design is a central learning objective in most introductory statistics courses. This article describes an activity, appropriate for a high school or introductory statistics course, designed to teach the concepts, values and pitfalls of random selection and assignment…
Xie, Rui-Fang; Shi, Zhi-Na; Li, Zhi-Cheng; Chen, Pei-Pei; Li, Yi-Min; Zhou, Xin
2015-04-01
Using Dachengqi Tang (DCQT) as a model, high performance liquid chromatography (HPLC) fingerprints were applied to optimize machine extracting process with the Box-Behnken experimental design. HPLC fingerprints were carried out to investigate the chemical ingredients of DCQT; synthetic weighing method based on analytic hierarchy process (AHP) and criteria importance through intercriteria correlation (CRITIC) was performed to calculate synthetic scores of fingerprints; using the mark ingredients contents and synthetic scores as indicators, the Box-Behnken design was carried out to optimize the process parameters of machine decocting process under high pressure for DCQT. Results of optimal process showed that the herb materials were soaked for 45 min and extracted with 9 folds volume of water in the decocting machine under the temperature of 140 °C till the pressure arrived at 0.25 MPa; then hot decoction was excreted to soak Dahuang and Mangxiao for 5 min. Finally, obtained solutions were mixed, filtrated and packed. It concluded that HPLC fingerprints combined with the Box-Behnken experimental design could be used to optimize extracting process of traditional Chinese medicine (TCM).
Providing guidance in virtual lab experimentation : the case of an experiment design tool
Efstathiou, Charalampos; Hovardas, Tasos; Xenofontos, Nikoletta A.; Zacharia, Zacharias C.; de Jong, Ton A.J.M.; Anjewierden, Anjo; van Riesen, Siswa A.N.
2018-01-01
The present study employed a quasi-experimental design to assess a computer-based tool, which was intended to scaffold the task of designing experiments when using a virtual lab for the process of experimentation. In particular, we assessed the impact of this tool on primary school students’
Experimental analysis and simulation calculation of the inductances of loosely coupled transformer
Kerui, Chen; Yang, Han; Yan, Zhang; Nannan, Gao; Ying, Pei; Hongbo, Li; Pei, Li; Liangfeng, Guo
2017-11-01
The experimental design of iron-core wireless power transmission system is designed, and an experimental model of loosely coupled transformer is built. Measuring the air gap on both sides of the transformer 15mm inductor under the parameters. The feasibility and feasibility of using the finite element method to calculate the coil inductance parameters of the loosely coupled transformer are analyzed. The system was modeled by ANSYS, and the magnetic field was calculated by finite element method, and the inductance parameters were calculated. The finite element method is used to calculate the inductive parameters of the loosely coupled transformer, and the basis for the accurate compensation of the capacitance of the wireless power transmission system is established.
International Nuclear Information System (INIS)
Ma, Guoyuan; Li, Xianguo
2007-01-01
The heat pump system with economizer coupled with scroll compressor can extend effectively its operating ranges and provide a technological method to enable the heat pump to run steadily and efficiently in severe weather conditions. The intermediate pressure, namely the working pressure of the refrigerant in the economizer, is an essential design parameter and affects crucially the performances of the heat pump system. According to the exergetic model setup for the heat pump system based on the second law of thermodynamics, the influences of the intermediate pressure on the performances are comprehensively analyzed using experimental data of the heat pump prototype. It is found that the optimal relative intermediate pressure (RIP) is between 1.1 and 1.3
Wear prediction on total ankle replacement effect of design parameters
Saad, Amir Putra Bin Md; Harun, Muhamad Noor; Kadir, Mohammed Rafiq Abdul
2016-01-01
This book develops and analyses computational wear simulations of the total ankle replacement for the stance phase of gait cycle. The emphasis is put on the relevant design parameters. The book presents a model consisting of three components; tibial, bearing and talar representing their physiological functions.
Model parameter updating using Bayesian networks
International Nuclear Information System (INIS)
Treml, C.A.; Ross, Timothy J.
2004-01-01
This paper outlines a model parameter updating technique for a new method of model validation using a modified model reference adaptive control (MRAC) framework with Bayesian Networks (BNs). The model parameter updating within this method is generic in the sense that the model/simulation to be validated is treated as a black box. It must have updateable parameters to which its outputs are sensitive, and those outputs must have metrics that can be compared to that of the model reference, i.e., experimental data. Furthermore, no assumptions are made about the statistics of the model parameter uncertainty, only upper and lower bounds need to be specified. This method is designed for situations where a model is not intended to predict a complete point-by-point time domain description of the item/system behavior; rather, there are specific points, features, or events of interest that need to be predicted. These specific points are compared to the model reference derived from actual experimental data. The logic for updating the model parameters to match the model reference is formed via a BN. The nodes of this BN consist of updateable model input parameters and the specific output values or features of interest. Each time the model is executed, the input/output pairs are used to adapt the conditional probabilities of the BN. Each iteration further refines the inferred model parameters to produce the desired model output. After parameter updating is complete and model inputs are inferred, reliabilities for the model output are supplied. Finally, this method is applied to a simulation of a resonance control cooling system for a prototype coupled cavity linac. The results are compared to experimental data.
Electron work function-a promising guiding parameter for material design.
Lu, Hao; Liu, Ziran; Yan, Xianguo; Li, Dongyang; Parent, Leo; Tian, Harry
2016-04-14
Using nickel added X70 steel as a sample material, we demonstrate that electron work function (EWF), which largely reflects the electron behavior of materials, could be used as a guide parameter for material modification or design. Adding Ni having a higher electron work function to X70 steel brings more "free" electrons to the steel, leading to increased overall work function, accompanied with enhanced e(-)-nuclei interactions or higher atomic bond strength. Young's modulus and hardness increase correspondingly. However, the free electron density and work function decrease as the Ni content is continuously increased, accompanied with the formation of a second phase, FeNi3, which is softer with a lower work function. The decrease in the overall work function corresponds to deterioration of the mechanical strength of the steel. It is expected that EWF, a simple but fundamental parameter, may lead to new methodologies or supplementary approaches for metallic materials design or tailoring on a feasible electronic base.
International Nuclear Information System (INIS)
Ferrante, Patrizia; La Gennusa, Maria; Peri, Giorgia; Rizzo, Gianfranco; Scaccianoce, Gianluca
2016-01-01
The paper provides a contribution for populating database of three physical parameters needed to model energy performance of buildings with green roofs: “coverage ratio” (σ_f), leaf area index (LAI) and leaf temperature (T_f). On purpose, six plant species were investigated experimentally: Phyla nordiflora, Aptenia lancifolia, Mesembryanthenum barbatus, Gazania nivea, Gazania uniflora, and Sedum. Proper ranges of the cited parameters have been found for each species. The here indicated ranges of σ_f values refer to different growth levels of the species in the same lapse of time, that is four months. Single measured LAI values are also reported for the same plants. As for the T_f (upper and lower layer), ranges of revealed temperatures refer to those detected from 10:30 a.m. to 16:30 p.m. of a selected day. Additionally, the dependence of T_f on climatic parameters was investigated. A linear equation resulted the best fitting curve for all experimental T_f data and the corresponding solar radiation data (with autocorrelation coefficients between 0.80 and 0.98). Furthermore, the effect potentially produced on building energy consumption by these species was analyzed using a simulation tool. Estimated cooling energy savings range approximately between 8% and 20% depending on adopted plants. - Highlights: • Green roof modeling requires the knowledge of various physical parameters. • Coverage ratio, leaf area index and leaves temperatures were measured for six species. • A tentative correlation between leaf temperature and climatic parameters was shown. • A correlation between LAI and coverage ratio was checked and discussed. • Potential effects of studied species on building energy consumption were investigated.
Engineering Parameters in Bioreactor’s Design: A Critical Aspect in Tissue Engineering
Directory of Open Access Journals (Sweden)
Nasim Salehi-Nik
2013-01-01
Full Text Available Bioreactors are important inevitable part of any tissue engineering (TE strategy as they aid the construction of three-dimensional functional tissues. Since the ultimate aim of a bioreactor is to create a biological product, the engineering parameters, for example, internal and external mass transfer, fluid velocity, shear stress, electrical current distribution, and so forth, are worth to be thoroughly investigated. The effects of such engineering parameters on biological cultures have been addressed in only a few preceding studies. Furthermore, it would be highly inefficient to determine the optimal engineering parameters by trial and error method. A solution is provided by emerging modeling and computational tools and by analyzing oxygen, carbon dioxide, and nutrient and metabolism waste material transports, which can simulate and predict the experimental results. Discovering the optimal engineering parameters is crucial not only to reduce the cost and time of experiments, but also to enhance efficacy and functionality of the tissue construct. This review intends to provide an inclusive package of the engineering parameters together with their calculation procedure in addition to the modeling techniques in TE bioreactors.
Hong, Yoo-Seung; Cho, Chun-Hyung; Sung, Hyuk-Kee
2018-03-05
We performed numerical analysis and design parameter optimization of a silicon-based grating waveguide refractive index (RI) sensor. The performance of the grating waveguide RI sensor was determined by the full-width at half-maximum (FWHM) and the shift in the resonance wavelength in the transmission spectrum. The transmission extinction, a major figure-of-merit of an RI sensor that reflects both FWHM and resonance shift performance, could be significantly improved by the proper determination of three major grating waveguide parameters: duty ratio, grating period, and etching depth. We analyzed the transmission characteristics of the grating waveguide under various design parameter conditions using a finite-difference time domain method. We achieved a transmission extinction improvement of >26 dB under a given bioenvironmental target change by the proper choice of the design procedure and parameters. This design procedure and choice of appropriate parameters would enable the widespread application of silicon-based grating waveguide in high-performance RI biochemical sensor.
Experimental determination of solubility parameters of oils as a function of pressure
DEFF Research Database (Denmark)
Verdier, Sylvain Charles Roland; Duong, Diep; Andersen, Simon Ivar
2005-01-01
In this work, the solubility parameter of dead and live crude oils was measured at 303.15 K and up to 300 bar, using the internal pressure approach. An indirect technique was chosen, using thermal expansivities (determined from microcalorimetric measurements) and isothermal compressibilities (cal...... are measured and given as input. Therefore, a more appropriate characterization method should give better results....... (calculated from density measurements). This method was tested on seven pure compounds, and the deviation with literature data is method based on the refractive index was used to examine the validity of the results for the oils, and a deviation of ... parameter was also calculated from two cubic equations of state and compared to experimental results. In this case, the deviations are larger (up to 6.5 MPa1/2), whereas this approach gives accurate results for pure compounds. This might be due to the characterization procedure, because the volumes...
Scaffolded Instruction Improves Student Understanding of the Scientific Method & Experimental Design
D'Costa, Allison R.; Schlueter, Mark A.
2013-01-01
Implementation of a guided-inquiry lab in introductory biology classes, along with scaffolded instruction, improved students' understanding of the scientific method, their ability to design an experiment, and their identification of experimental variables. Pre- and postassessments from experimental versus control sections over three semesters…
Deng, Bin; Lundqvist, Mats; Fang, Qianqian; Carp, Stefan A
2018-03-01
largest deterioration due to cross-talk between signal channels. However, errors in optical images could be effectively controlled when experimental parameters were properly estimated during data acquisition and accounted for in the image processing procedure. Finally, optical images recovered using structural priors were, in general, less susceptible to experimental errors; however, lesion contrasts were more sensitive to errors when tumor locations were used as a priori info. Findings in this simulation study can provide guidelines for system design and operation in optical breast imaging studies.
Optomechanical parameter estimation
International Nuclear Information System (INIS)
Ang, Shan Zheng; Tsang, Mankei; Harris, Glen I; Bowen, Warwick P
2013-01-01
We propose a statistical framework for the problem of parameter estimation from a noisy optomechanical system. The Cramér–Rao lower bound on the estimation errors in the long-time limit is derived and compared with the errors of radiometer and expectation–maximization (EM) algorithms in the estimation of the force noise power. When applied to experimental data, the EM estimator is found to have the lowest error and follow the Cramér–Rao bound most closely. Our analytic results are envisioned to be valuable to optomechanical experiment design, while the EM algorithm, with its ability to estimate most of the system parameters, is envisioned to be useful for optomechanical sensing, atomic magnetometry and fundamental tests of quantum mechanics. (paper)
Optimization of Experimental Model Parameter Identification for Energy Storage Systems
Directory of Open Access Journals (Sweden)
Rosario Morello
2013-09-01
Full Text Available The smart grid approach is envisioned to take advantage of all available modern technologies in transforming the current power system to provide benefits to all stakeholders in the fields of efficient energy utilisation and of wide integration of renewable sources. Energy storage systems could help to solve some issues that stem from renewable energy usage in terms of stabilizing the intermittent energy production, power quality and power peak mitigation. With the integration of energy storage systems into the smart grids, their accurate modeling becomes a necessity, in order to gain robust real-time control on the network, in terms of stability and energy supply forecasting. In this framework, this paper proposes a procedure to identify the values of the battery model parameters in order to best fit experimental data and integrate it, along with models of energy sources and electrical loads, in a complete framework which represents a real time smart grid management system. The proposed method is based on a hybrid optimisation technique, which makes combined use of a stochastic and a deterministic algorithm, with low computational burden and can therefore be repeated over time in order to account for parameter variations due to the battery’s age and usage.
Directory of Open Access Journals (Sweden)
Shasanka Shekhar Panda
2014-01-01
Full Text Available Background: The objective of the following study is to determine and to compare the different morphological parameters with duration of obstruction created experimentally in unilateral upper ureters of rats. Materials and Methods: Unilateral upper ureteric obstruction was created in 60 adult Wistar rats that were reversed after predetermined intervals. Rats were sacrificed and ipsilateral kidneys were subjected for analysis of morphological parameters such as renal height, cranio-caudal diameter, antero-posterior diameter, lateral diameter, volume of the pelvis and average cortical thickness: Renal height. Results: Renal height and cranio-caudal diameter of renal pelvis after ipsilateral upper ureteric obstruction started rising as early as 7 days of creating obstruction and were affected earlier than antero-posterior and lateral diameter and also were reversed earlier than other parameters after reversal of obstruction. Renal cortical thickness and volume of the pelvis were affected after prolonged obstruction (> 3 weeks and were the late parameters to be reversed after reversal of obstruction. Conclusions: Cranio-caudal diameter and renal height were the early morphological parameters to be affected and reversed after reversal of obstruction in experimentally created ipsilateral upper ureteric obstruction.
Dopico-García, M S; Valentão, P; Guerra, L; Andrade, P B; Seabra, R M
2007-01-30
An experimental design was applied for the optimization of extraction and clean-up processes of phenolic compounds and organic acids from white "Vinho Verde" grapes. The developed analytical method consisted in two steps: first a solid-liquid extraction of both phenolic compounds and organic acids and then a clean-up step using solid-phase extraction (SPE). Afterwards, phenolic compounds and organic acids were determined by high-performance liquid chromatography (HPLC) coupled to a diode array detector (DAD) and HPLC-UV, respectively. Plackett-Burman design was carried out to select the significant experimental parameters affecting both the extraction and the clean-up steps. The identified and quantified phenolic compounds were: quercetin-3-O-glucoside, quercetin-3-O-rutinoside, kaempferol-3-O-rutinoside, isorhamnetin-3-O-glucoside, quercetin, kaempferol and epicatechin. The determined organic acids were oxalic, citric, tartaric, malic, shikimic and fumaric acids. The obtained results showed that the most important variables were the temperature (40 degrees C) and the solvent (acid water at pH 2 with 5% methanol) for the extraction step and the type of sorbent (C18 non end-capped) for the clean-up step.
Bhushan, Awani; Panda, S. K.
2018-05-01
The influence of bimodularity (different stress ∼ strain behaviour in tension and compression) on fracture behaviour of graphite specimens has been studied with fracture toughness (KIc), critical J-integral (JIc) and critical strain energy release rate (GIc) as the characterizing parameter. Bimodularity index (ratio of tensile Young's modulus to compression Young's modulus) of graphite specimens has been obtained from the normalized test data of tensile and compression experimentation. Single edge notch bend (SENB) testing of pre-cracked specimens from the same lot have been carried out as per ASTM standard D7779-11 to determine the peak load and critical fracture parameters KIc, GIc and JIc using digital image correlation technology of crack opening displacements. Weibull weakest link theory has been used to evaluate the mean peak load, Weibull modulus and goodness of fit employing two parameter least square method (LIN2), biased (MLE2-B) and unbiased (MLE2-U) maximum likelihood estimator. The stress dependent elasticity problem of three-dimensional crack progression behaviour for the bimodular graphite components has been solved as an iterative finite element procedure. The crack characterizing parameters critical stress intensity factor and critical strain energy release rate have been estimated with the help of Weibull distribution plot between peak loads versus cumulative probability of failure. Experimental and Computational fracture parameters have been compared qualitatively to describe the significance of bimodularity. The bimodular influence on fracture behaviour of SENB graphite has been reflected on the experimental evaluation of GIc values only, which has been found to be different from the calculated JIc values. Numerical evaluation of bimodular 3D J-integral value is found to be close to the GIc value whereas the unimodular 3D J-value is nearer to the JIc value. The significant difference between the unimodular JIc and bimodular GIc indicates that
Tokamak experimental power reactor conceptual design. Volume II
International Nuclear Information System (INIS)
1976-08-01
Volume II contains the following appendices: (1) summary of EPR design parameters, (2) impurity control, (3) plasma computational models, (4) structural support system, (5) materials considerations for the primary energy conversion system, (6) magnetics, (7) neutronics penetration analysis, (8) first wall stress analysis, (9) enrichment of isotopes of hydrogen by cryogenic distillation, and (10) noncircular plasma considerations
Defining New Parameters for Green Engineering Design of Treatment Reactors
Directory of Open Access Journals (Sweden)
Susana Boeykens
2016-06-01
Full Text Available This study proposes a green way to design Plug Flow Reactors (PFR that use biodegradable polymer solutions, capable of contaminant retaining, for industrial wastewater treatment. Usually, to the design of a PFR, the reaction rate is determined by tests on a Continuous Stirred-Tank Reactor (CSTR, these generate toxic effluents and also increase the cost of the design. In this work, empirical expressions (called “slip functions”, in terms of the average concentration of the contaminant, were developed through the study of the transport behaviour of CrVI into solutions of xanthan gum. “In situ” XRµF was selected as a no-invasive micro-technique to determine local concentrations. Slip functions were used with laboratory PFR experiments planned in similar conditions, to obtain useful dimensionless parameters for the industrial design.
PARAMETER DESIGN OF AN ELECTRO PNEUMATIC SYSTEM USING RESPONSE SURFACE METHODOLOGY
Rajakannu Amuthakkannan
2014-01-01
In the present scenario, more number of software based mechanical systems are coming with advanced technologies like embedded system control or computer system control for various industrial applications. Mechatronics is a popular technology in the evolutionary process of modern engineering automation system design. The ineffective parameter design in software based mechatronics system may produce the severe consequences in the application field, even there is a chance of accidents. So, caref...
Computational design and experimental validation of new thermal barrier systems
Energy Technology Data Exchange (ETDEWEB)
Guo, Shengmin [Louisiana State Univ., Baton Rouge, LA (United States)
2015-03-31
The focus of this project is on the development of a reliable and efficient ab initio based computational high temperature material design method which can be used to assist the Thermal Barrier Coating (TBC) bond-coat and top-coat design. Experimental evaluations on the new TBCs are conducted to confirm the new TBCs’ properties. Southern University is the subcontractor on this project with a focus on the computational simulation method development. We have performed ab initio density functional theory (DFT) method and molecular dynamics simulation on screening the top coats and bond coats for gas turbine thermal barrier coating design and validation applications. For experimental validations, our focus is on the hot corrosion performance of different TBC systems. For example, for one of the top coatings studied, we examined the thermal stability of TaZr_{2.75}O_{8} and confirmed it’s hot corrosion performance.
Handley, Margaret A; Schillinger, Dean; Shiboski, Stephen
2011-01-01
Although randomized controlled trials are often a gold standard for determining intervention effects, in the area of practice-based research (PBR), there are many situations in which individual randomization is not possible. Alternative approaches to evaluating interventions have received increased attention, particularly those that can retain elements of randomization such that they can be considered "controlled" trials. Methodological design elements and practical implementation considerations for two quasi-experimental design approaches that have considerable promise in PBR settings--the stepped-wedge design, and a variant of this design, a wait-list cross-over design, are presented along with a case study from a recent PBR intervention for patients with diabetes. PBR-relevant design features include: creation of a cohort over time that collects control data but allows all participants (clusters or patients) to receive the intervention; staggered introduction of clusters; multiple data collection points; and one-way cross-over into the intervention arm. Practical considerations include: randomization versus stratification, training run in phases; and extended time period for overall study completion. Several design features of practice based research studies can be adapted to local circumstances yet retain elements to improve methodological rigor. Studies that utilize these methods, such as the stepped-wedge design and the wait-list cross-over design, can increase the evidence base for controlled studies conducted within the complex environment of PBR.
Factorial experimental design intended for the optimization of the alumina purification conditions
Brahmi, Mounaouer; Ba, Mohamedou; Hidri, Yassine; Hassen, Abdennaceur
2018-04-01
The objective of this study was to determine the optimal conditions by using the experimental design methodology for the removal of some impurities associated with the alumina. So, three alumina qualities of different origins were investigated under the same conditions. The application of full-factorial designs on the samples of different qualities of alumina has followed the removal rates of the sodium oxide. However, a factorial experimental design was developed to describe the elimination of sodium oxide associated with the alumina. The experimental results showed that chemical analyze followed by XRF prior treatment of the samples, provided a primary idea concerning these prevailing impurities. Therefore, it appeared that the sodium oxide constituted the largest amount among all impurities. After the application of experimental design, analysis of the effectors different factors and their interactions showed that to have a better result, we should reduce the alumina quantity investigated and by against increase the stirring time for the first two samples, whereas, it was necessary to increase the alumina quantity in the case of the third sample. To expand and improve this research, we should take into account all existing impurities, since we found during this investigation that the levels of partial impurities increased after the treatment.
Energy Technology Data Exchange (ETDEWEB)
Jacob, Y.P.; Haanappel, V.A.C.; Stroosnijder, M.F. [Commission of the European Communities, Ispra (Italy). Joint Research Centre; Caudron, E.; Buscail, H. [Lab. Vellave sur l' Elaboration et l' Etude des Materiaux, Equipe locale Univ. Blaise-Pascal Clermont-Fd 2 (France)
2001-07-01
In this study the importance of experimental parameters for the cyclic oxidation behaviour of chromium is discussed. In particular, the effect of different batches, sample geometry, maximum temperature during cyclic oxidation tests, and the effect of isothermal hold-time in relation to the oxidation behaviour are investigated in more detail. It is shown that small differences in the experimental method or material properties could already significantly influence the oxidation kinetics of the material under investigation. Consequently, poorly chosen and/or characterised experimental conditions can cause misleading results and even wrong conclusions. (orig.)
Parameter and state estimation of experimental chaotic systems using synchronization
Quinn, John C.; Bryant, Paul H.; Creveling, Daniel R.; Klein, Sallee R.; Abarbanel, Henry D. I.
2009-07-01
We examine the use of synchronization as a mechanism for extracting parameter and state information from experimental systems. We focus on important aspects of this problem that have received little attention previously and we explore them using experiments and simulations with the chaotic Colpitts oscillator as an example system. We explore the impact of model imperfection on the ability to extract valid information from an experimental system. We compare two optimization methods: an initial value method and a constrained method. Each of these involves coupling the model equations to the experimental data in order to regularize the chaotic motions on the synchronization manifold. We explore both time-dependent and time-independent coupling and discuss the use of periodic impulse coupling. We also examine both optimized and fixed (or manually adjusted) coupling. For the case of an optimized time-dependent coupling function u(t) we find a robust structure which includes sharp peaks and intervals where it is zero. This structure shows a strong correlation with the location in phase space and appears to depend on noise, imperfections of the model, and the Lyapunov direction vectors. For time-independent coupling we find the counterintuitive result that often the optimal rms error in fitting the model to the data initially increases with coupling strength. Comparison of this result with that obtained using simulated data may provide one measure of model imperfection. The constrained method with time-dependent coupling appears to have benefits in synchronizing long data sets with minimal impact, while the initial value method with time-independent coupling tends to be substantially faster, more flexible, and easier to use. We also describe a method of coupling which is useful for sparse experimental data sets. Our use of the Colpitts oscillator allows us to explore in detail the case of a system with one positive Lyapunov exponent. The methods we explored are easily
Permanently split capacitor motor-study of the design parameters
Sarac, Vasilija; Stefanov, Goce
2017-09-01
Paper analyzes the influence of various design parameters on torque of permanently split capacitor motor. Motor analytical model is derived and it is used for calculating the performance characteristics of basic motor model. The acquired analytical model is applied in optimization software that uses genetic algorithms (GA) as an optimization method. Optimized motor model with increased torque is derived by varying three motor parameters in GA program: winding turns ratio, average air gap flux density and motor stack length. Increase of torque has been achieved for nominal operation but also at motor starting. Accuracy of the derived models is verified by Simulink. The acquired values of several motor parameters from transient characteristics of Simulink models are compared with the corresponding values obtained from analytical models of both motors, basic and optimized. Numerical analysis, based on finite element method (FEM), is also performed for both motor models. As a result of the FEM analysis, magnetic flux density in motor cross-section is calculated and adequate conclusions are derived in relation to core saturation and air gap flux density in both motor models.
Energy Technology Data Exchange (ETDEWEB)
Phu, Nguyen Minh; Trinh, Nguyen Thi Minh [Vietnam National University, Ho Chi Minh City (Viet Nam)
2016-07-15
Today the helical coil heat exchanger is being employed widely due to its dominant advantages. In this study, a mathematical model was established to predict off-design works of the helical heat exchanger. The model was based on the LMTD and e-NTU methods, where a LMTD correction factor was taken into account to increase accuracy. An experimental apparatus was set-up to validate the model. Results showed that errors of thermal duty, outlet hot fluid temperature, outlet cold fluid temperature, shell-side pressure drop, and tube-side pressure drop were respectively +-5%, +-1%, +-1%, +-5% and +-2%. Diagrams of dimensionless operating parameters and a regression function were also presented as design-maps, a fast calculator for usage in design and operation of the exchanger. The study is expected to be a good tool to estimate off-design conditions of the single-phase helical heat exchangers.
Basic design parameters for the new PRR-1 stack
International Nuclear Information System (INIS)
Leopando, L.S.
1994-01-01
This report presents the results of work done to establish the basic design parameters of the new stack of the Philippine Research Reactor-1 (PRR-1). The work was undertaken to assure that the radioactive air emissions of the PRR-1, under both accident and normal operating conditions, will comply with modern safety practices. The work was done during June and July 1994. (author). 6 refs., 13 figs., 13 tabs
The design of virtual double-parameter nuclear spectrum acquisition system based on LabVIEW
International Nuclear Information System (INIS)
Liu Songqiu; Chen Chuan; Lei Wuhu
2001-01-01
This paper introduces the design of virtual double-parameter nuclear spectrum acquisition system based on LabVIEW and NI multifunction DAQ board, and the use of it to measure the double-parameter nuclear spectrum
International Nuclear Information System (INIS)
Martin Sanchez, A.; Vera Tome, F.; Caceres Marzal, D.; Bland, C.J.
1994-01-01
A pulse-height spectrum of alpha-particle emissions at discrete energies can be fitted by the peak-shape functions generated by combining asymmetric truncated exponential functions with a symmetric Gaussian distribution. These functions have been applied successfully by several workers. A correlation was previously found between the variance of the symmetric Gaussian portion of the fitting function, and the parameter characterising the principal exponential tailing function. The results of a more detailed experimental study are reported, which involve varying the angle and the distance between the source and the detector. This analysis shows that the parameters of the symmetric and asymmetric parts of the fitted functions seem to depend on either the detector or the source. These parameters are influenced by the energy loss suffered by the alpha-particles as well as by the efficiency of charge collection in the solid-state detector. (orig.)
Overview of design development of FCC-hh Experimental Interaction Regions
AUTHOR|(CDS)2082479; Abelleira, Jose; Cruz Alaniz, Emilia; Van Riesen-Haupt, Leon; Benedikt, Michael; Besana, Maria Ilaria; Buffat, Xavier; Burkhardt, Helmut; Cerutti, Francesco; Langner, Andy Sven; Martin, Roman; Riegler, Werner; Schulte, Daniel; Tomas Garcia, Rogelio; Appleby, Robert Barrie; Rafique, Haroon; Barranco Garcia, Javier; Pieloni, Tatiana; Boscolo, Manuela; Collamati, Francesco; Nevay, Laurence James; Hofer, Michael
2017-01-01
The experimental interaction region (EIR) is one of the key areas that define the performance of the Future Circular Collider. In this overview we will describe the status and the evolution of the design of EIR of FCC-hh, focusing on design of the optics, energy deposition in EIR elements, beam-beam effects and machine detector interface issues.
Second preliminary design of JAERI experimental fusion reactor (JXFR)
International Nuclear Information System (INIS)
Sako, Kiyoshi; Tone, Tatsuzo; Seki, Yasushi; Iida, Hiromasa; Yamato, Harumi
1979-06-01
Second preliminary design of a tokamak experimental fusion reactor to be built in the near future has been performed. This design covers overall reactor system including plasma characteristics, reactor structure, blanket neutronics radiation shielding, superconducting magnets, neutral beam injector, electric power supply system, fuel recirculating system, reactor cooling and tritium recovery systems and maintenance scheme. Safety analyses of the reactor system have been also performed. This paper gives a brief description of the design as of January, 1979. The feasibility study of raising the power density has been also studied and is shown as appendix. (author)
Conceptual design study of Fusion Experimental Reactor (FY87FER)
International Nuclear Information System (INIS)
1988-05-01
The design study of Fusion Experimental Reactor(FER) which has been proposed to be the next step fusion device has been conducted by JAERI Reactor System Laboratory since 1982 and by FER design team since 1984. This is the final report of the FER design team program and describes the results obtained in FY1987 (partially in FY1986) activities. The contents of this report consist of the reference design which is based on the guideline in FY1986 by the Subcomitees set up in Nuclear Fusion Council of Atomic Energy Commission of Japan, the Low-Physics-Risk reactor design for achieving physics mission more reliably and the system study of FER design candidates including above two designs. (author)
International Nuclear Information System (INIS)
Roudeau, P.; Stocchi, A.; Ciuchini, M.; Lubicz, V.; D'Agostini, G.; Franco, E.; Martinelli, G.; Parodi, F.
2000-12-01
Within the Standard Model, a review of the current determination of the sides and angles of the CKM unitarity triangle is presented, using experimental constraints from the measurements of |ε K |, |V ub /V cb |, Δm d and from the limit on Δm s , available in September 2000. Results from the experimental search for B 0 s -B-bar 0 s oscillations are introduced in the present analysis using the likelihood. Special attention is devoted to the determination of the theoretical uncertainties. The purpose of the analysis is to infer regions where the parameters of interest lie with given probabilities. The BaBar '95% C.L. scanning' method is also commented. (authors)
Optimization Of Blasting Design Parameters On Open Pit Bench A Case Study Of Nchanga Open Pits
Directory of Open Access Journals (Sweden)
Victor Mwango Bowa
2015-08-01
Full Text Available Abstract In hard rock mining blasting is the most productive excavation technique applied to fragment insitu rock to the required size for efficient loading and crushing. In order to blast the insitu rock to the desired fragment size blast design parameter such as bench height hole diameter spacing burden hole length bottom charge specific charge and rock factor are considered. The research was carried out as a practical method on Nchanga Open Pits NOP ore Bench to optimize the blasting design parameters that can yield the required fragmentation size thereby reducing the shovel loading times and maximizing efficiency of the subsequent mining unit operations such as hauling and crushing. Fragmentation characteristics such as the mean fragment size were measured by means of a digital measuring tape and predicated using the Kuznetsov equation and rock factor value of ore bench was calculated using Lilly 1986 equations by means of rock characteristics. Traditional blasting design parameters were acquired for NOP and modified using Langerfors and Sharma P.A approaches. Several blast operations were conducted using both traditional and modified blasting design parameters on the same ore bench with the same geological conditions. Loading times of the shovel and fragment sizes were obtained after the blasts from ore bench where both the traditional and modified blasting design parameters were applied. Results show that mean fragment size and loading times were reduced from 51cm and 12minutes to 22cm and 3minutes where traditional and modified blasting design parameters were applied respectively.
Improvements in welding parameters for a new design of zircaloy-4 tube-end plug joints
International Nuclear Information System (INIS)
Martinez, R.L.; Fernandez, L.; Corso, H.L.; Ausas, J; Santisteban, J.R.
2010-01-01
This work presents the experimental results for the characterization of welds using a new design for zircaloy-4 tube-end plug joints, applicable to the production of fuel elements for the Atucha I Nuclear Plant. Test specimens were prepared following the new joint design and were welded using orbital welding equipment. Hydrogen content was measured in the different welding areas, and corrosion tests, and mechanical and microstructural descriptions were carried out, obtaining values that meet the current production standards. We reported previously that test samples welded in equipment with a smaller camera showed some relatively high hydrogen levels, together with alterations in the welded zone in the corrosion tests. Given these results, new tests were undertaken to optimize the welding parameters, being very careful with the purity of the welding atmosphere and in the handling of the samples. The intensity of the welding current was increased slightly to obtain better penetration of the material, without significantly increasing the heat input. The traction resistance values improved, reducing the hydrogen content to well below the maximum allowed by the standards (25 ppm) in all the welding zones and obtaining satisfactory results in the corrosion tests
The experimental Balzac program at Masurca in support of the design of Super Phenix 2
International Nuclear Information System (INIS)
Sztark, H.; d'Angelo, A.; Soule, R.; Granget, G.
1986-09-01
The Balzac experimental program, performed in the Masurca critical assembly at Cadarache since 1985, is designed for the validation of the neutron physics requirements related to the physical options of the SPX2 project. Geometrically simple configurations are chosen in which parameters, typical for those physical options, are varied in a systematic manner while the basic fissile composition is kept the same. Measurements will be made especially of the critical mass, the distributions of reaction rates, spectral indices, 10 B(n,α) reaction and gamma-ray heating in particular in the control-rod and in internal storage regions. Reactivity effects of (UPu)O 2 isotopic composition variations and of different control-rod absorber configurations will be also measured using the MSM technique
Energy Technology Data Exchange (ETDEWEB)
Jamil, Zadariana [Department of Civil Engineering, Faculty of Engineering, University of Malaya (Malaysia); Faculty of Civil Engineering, Technology University of MARA (Malaysia); Mohamad Annuar, Mohamad Suffian; Vikineswary, S. [Institute of Biological Sciences, University of Malaya (Malaysia); Ibrahim, Shaliza [Department of Civil Engineering, Faculty of Engineering, University of Malaya (Malaysia)
2009-09-15
Phototrophic hydrogen production by indigenous purple non-sulfur bacteria, Rhodopseudomonas palustris PBUM001 from palm oil mill effluent (POME) was optimized using response surface methodology (RSM). The process parameters studied include inoculum sizes (% v/v), POME concentration (% v/v), light intensity (klux), agitation (rpm) and pH. The experimental data on cumulative hydrogen production and COD reduction were fitted into a quadratic polynomial model using response surface regression analysis. The path to optimal process conditions was determined by analyzing response surface three-dimensional surface plot and contour plot. Statistical analysis on experimental data collected following Box-Behnken design showed that 100% (v/v) POME concentration, 10% (v/v) inoculum size, light intensity at 4.0 klux, agitation rate at 250 rpm and pH of 6 were the best conditions. The maximum predicted cumulative hydrogen production and COD reduction obtained under these conditions was 1.05 ml H{sub 2}/ml POME and 31.71% respectively. Subsequent verification experiments at optimal process values gave the maximum yield of cumulative hydrogen at 0.66 {+-} 0.07 ml H{sub 2}/ml POME and COD reduction at 30.54 {+-} 9.85%. (author)
Nagy, M.; Behúlová, M.
2017-11-01
Nowadays, the laser technology is used in a wide spectrum of applications, especially in engineering, electronics, medicine, automotive, aeronautic or military industries. In the field of mechanical engineering, the laser technology reaches the biggest increase in the automotive industry, mainly due to the introduction of automation utilizing 5-axial movements. Modelling and numerical simulation of laser welding processes has been exploited with many advantages for the investigation of physical principles and complex phenomena connected with this joining technology. The paper is focused on the application of numerical simulation to the design of welding parameters for the circumferential laser welding of thin-walled exhaust pipes from theAISI 304 steel for automotive industry. Using the developed and experimentally verified simulation model for laser welding of tubes, the influence of welding parameters including the laser velocity from 30 mm.s-1 to 60 mm.s-1 and the laser power from 500 W to 1200 W on the temperature fields and dimensions of fusion zone was investigated using the program code ANSYS. Based on obtained results, the welding schedule for the laser beam welding of thin-walled tubes from the AISI 304 steel was suggested.
Design of JT-60SA magnets and associated experimental validations
International Nuclear Information System (INIS)
Zani, L.; Barabaschi, P.; Peyrot, M.; Meunier, L.; Tomarchio, V.; Duglue, D.; Decool, P.; Torre, A.; Marechal, J.L.; Della Corte, A.; Di Zenobio, A.; Muzzi, L.; Cucchiaro, A.; Turtu, S.; Ishida, S.; Yoshida, K.; Tsuchiya, K.; Kizu, K.; Murakami, H.
2011-01-01
In the framework of the JT-60SA project, aiming at upgrading the present JT-60U tokamak toward a fully superconducting configuration, the detailed design phase led to adopt for the three main magnet systems a brand new design. Europe (EU) is expected to provide to Japan (JA) the totality of the toroidal field (TF) magnet system, while JA will provide both Equilibrium field (EF) and Central Solenoid (CS) systems. All magnet designs were optimized trough the past years and entered in parallel into extensive experimentally-based phases of concept validation, which came to maturation in the years 2009 and 2010. For this, all magnet systems were investigated by mean of dedicated samples, e.g. conductor and joint samples designed, manufactured and tested at full scale in ad hoc facilities either in EU or in JA. The present paper, after an overall description of magnet systems layouts, presents in a general approach the different experimental campaigns dedicated to qualification design and manufacture processes of either coils, conductors and electrical joints. The main results with the associated analyses are shown and the main conclusions presented, especially regarding their contribution to consolidate the triggering of magnet mass production. The status of respective manufacturing stages in EU and in JA are also evoked. (authors)
Design and experimental verification of a dual-band metamaterial filter
Zhu, Hong-Yang; Yao, Ai-Qin; Zhong, Min
2016-10-01
In this paper, we present the design, simulation, and experimental verification of a dual-band free-standing metamaterial filter operating in a frequency range of 1 THz-30 THz. The proposed structure consists of periodically arranged composite air holes, and exhibits two broad and flat transmission bands. To clarify the effects of the structural parameters on both resonant transmission bands, three sets of experiments are performed. The first resonant transmission band shows a shift towards higher frequency when the side width w 1 of the main air hole is increased. In contrast, the second resonant transmission band displays a shift towards lower frequency when the side width w 2 of the sub-holes is increased, while the first resonant transmission band is unchanged. The measured results indicate that these resonant bands can be modulated individually by simply optimizing the relevant structural parameters (w 1 or w 2) for the required band. In addition, these resonant bands merge into a single resonant band with a bandwidth of 7.7 THz when w 1 and w 2 are optimized simultaneously. The structure proposed in this paper adopts different resonant mechanisms for transmission at different frequencies and thus offers a method to achieve a dual-band and low-loss filter. Project supported by the Doctorate Scientific Research Foundation of Hezhou University, China (Grant No. HZUBS201503), the Promotion of the Basic Ability of Young and Middle-aged Teachers in Universities Project of Guangxi Zhuang Autonomous Region, China (Grant No. KY2016YB453), the Guangxi Colleges and Universities Key Laboratory Symbolic Computation, China, Engineering Data Processing and Mathematical Support Autonomous Discipline Project of Hezhou University, China (Grant No. 2016HZXYSX01).
Inverse problems in the design, modeling and testing of engineering systems
Alifanov, Oleg M.
1991-01-01
Formulations, classification, areas of application, and approaches to solving different inverse problems are considered for the design of structures, modeling, and experimental data processing. Problems in the practical implementation of theoretical-experimental methods based on solving inverse problems are analyzed in order to identify mathematical models of physical processes, aid in input data preparation for design parameter optimization, help in design parameter optimization itself, and to model experiments, large-scale tests, and real tests of engineering systems.
Entropy-Based Experimental Design for Optimal Model Discrimination in the Geosciences
Directory of Open Access Journals (Sweden)
Wolfgang Nowak
2016-11-01
Full Text Available Choosing between competing models lies at the heart of scientific work, and is a frequent motivation for experimentation. Optimal experimental design (OD methods maximize the benefit of experiments towards a specified goal. We advance and demonstrate an OD approach to maximize the information gained towards model selection. We make use of so-called model choice indicators, which are random variables with an expected value equal to Bayesian model weights. Their uncertainty can be measured with Shannon entropy. Since the experimental data are still random variables in the planning phase of an experiment, we use mutual information (the expected reduction in Shannon entropy to quantify the information gained from a proposed experimental design. For implementation, we use the Preposterior Data Impact Assessor framework (PreDIA, because it is free of the lower-order approximations of mutual information often found in the geosciences. In comparison to other studies in statistics, our framework is not restricted to sequential design or to discrete-valued data, and it can handle measurement errors. As an application example, we optimize an experiment about the transport of contaminants in clay, featuring the problem of choosing between competing isotherms to describe sorption. We compare the results of optimizing towards maximum model discrimination with an alternative OD approach that minimizes the overall predictive uncertainty under model choice uncertainty.
Vinnakota, Kalyan C; Beard, Daniel A; Dash, Ranjan K
2009-01-01
Identification of a complex biochemical system model requires appropriate experimental data. Models constructed on the basis of data from the literature often contain parameters that are not identifiable with high sensitivity and therefore require additional experimental data to identify those parameters. Here we report the application of a local sensitivity analysis to design experiments that will improve the identifiability of previously unidentifiable model parameters in a model of mitochondrial oxidative phosphorylation and tricaboxylic acid cycle. Experiments were designed based on measurable biochemical reactants in a dilute suspension of purified cardiac mitochondria with experimentally feasible perturbations to this system. Experimental perturbations and variables yielding the most number of parameters above a 5% sensitivity level are presented and discussed.
International Nuclear Information System (INIS)
Elnajjar, Emad; Selim, Mohamed Y.E.; Hamdan, Mohammad O.
2013-01-01
Highlights: • The effect of using variable LPG is studied. • Five fuels with propane to butane % volume ratio are: 100-70-55-25-0. • 100% Propane composition shows the highest noise levels with similar performance. • At 45° BTDC injection timing 55% Propane LPG the only fuel experience knocking. • LPG fuels gave similar engine performance, with differences in levels of noise. - Abstract: The present work investigates experimentally the effect of LPG fuel with different composition and engine parameters on the performance of a dual compression engine. Five different blends of LPG fuels are used with Propane to Butane volume ratio of 100:0, 70:30, 55:45, 25:75, and 0:100. A single cylinder, naturally aspirated, four strokes, indirectly injected, water cooled modified Ricardo E6 engine, is used in this study. The study is carried out by measuring the cylinder pressure, engine load, engine speed, crank angle, and the fuel’s flow rate. The engine performance under variable LPG fuel composition, engine load, pilot fuel injection timing, compression ratio, pilot fuel mass and engine speed, are estimated by comparing the following engine parameters: the cylinder maximum pressure, the indicated mean effective pressure, the maximum rate of pressure rise, and the thermal efficiency. The experimental data indicates that the engine parameters are playing a major role on the engine’s performance. Different LPG fuel composition did not show a major effect on the engine efficiency but directly impacted the levels of generated combustion noise
Directory of Open Access Journals (Sweden)
Biswal Sadjyot
2017-01-01
Full Text Available The focus of the paper is on designing a suspension system for a medium downforce small Formula type race car. The paper not only focusses on step by step design for a double wishbone type suspension but will also show the use and role of kinematics software in determining the optimized suspension of the car. The paper will also focus on the use of tire data in determining suspension parameters and the design of the double wishbone suspension. Various parameters, their design importance and the process to optimize them according to suspension design goals will be covered. The easiest and best ways to change the suspension parameters to get the best results will also be covered.
Energy Technology Data Exchange (ETDEWEB)
Bunting, Bruce G [ORNL
2012-10-01
The automotive and engine industries are in a period of very rapid change being driven by new emission standards, new types of after treatment, new combustion strategies, the introduction of new fuels, and drive for increased fuel economy and efficiency. The rapid pace of these changes has put more pressure on the need for modeling of engine combustion and performance, in order to shorten product design and introduction cycles. New combustion strategies include homogeneous charge compression ignition (HCCI), partial-premixed combustion compression ignition (PCCI), and dilute low temperature combustion which are being developed for lower emissions and improved fuel economy. New fuels include bio-fuels such as ethanol or bio-diesel, drop-in bio-derived fuels and those derived from new crude oil sources such as gas-to-liquids, coal-to-liquids, oil sands, oil shale, and wet natural gas. Kinetic modeling of the combustion process for these new combustion regimes and fuels is necessary in order to allow modeling and performance assessment for engine design purposes. In this research covered by this CRADA, ORNL developed and supplied experimental data related to engine performance with new fuels and new combustion strategies along with interpretation and analysis of such data and consulting to Reaction Design, Inc. (RD). RD performed additional analysis of this data in order to extract important parameters and to confirm engine and kinetic models. The data generated was generally published to make it available to the engine and automotive design communities and also to the Reaction Design Model Fuels Consortium (MFC).
ITER [International Thermonuclear Experimental Reactor] reactor building design study
International Nuclear Information System (INIS)
Thomson, S.L.; Blevins, J.D.; Delisle, M.W.
1989-01-01
The International Thermonuclear Experimental Reactor (ITER) is at the midpoint of a two-year conceptual design. The ITER reactor building is a reinforced concrete structure that houses the tokamak and associated equipment and systems and forms a barrier between the tokamak and the external environment. It provides radiation shielding and controls the release of radioactive materials to the environment during both routine operations and accidents. The building protects the tokamak from external events, such as earthquakes or aircraft strikes. The reactor building requirements have been developed from the component designs and the preliminary safety analysis. The equipment requirements, tritium confinement, and biological shielding have been studied. The building design in progress requires continuous iteraction with the component and system designs and with the safety analysis. 8 figs
Modeling, design and experimental validation of a small-sized magnetic gear
Zanis, R.; Borisavljevic, A.; Jansen, J.W.; Lomonova, E.A.
2013-01-01
A magnetostatic analytical model is created to analyze and design a small-sized magnetic gear for a robotic application. Through a parameter variation study, it is found that the inner rotor magnet height is highly influential to the torque, and based on which, the design is performed. Several
Conceptual design study of fusion experimental reactor (FER)
International Nuclear Information System (INIS)
1986-11-01
Since 1980 the design study has been conducted at JAERI for the Fusion Experimental Reactor (FER) which has been proposed to be the next machine to JT-60 in the Japanese long term program of fusion reactor development. During two years from 1984 to 1985 FER concept was reviewed and redesigned. This report is the summary of the results obtained in the review and redesign activities in 1984 and 85. In the first year FER concept was discussed again and its frame work was reestablished. According to the new frame work the major reactor components of FER were designed. In the second year the whole plant system design including plant layout plan was conducted as well as the more detailed design analysis of the reactor conponents. The newly established frame for FER design is as follows: 1) Plasma : Self-ignition. 2) Operation scenario : Quasi-steady state operation with long burn pulse. 3) Neutron fluence on the first wall : 0.3 MWY/M 2 . 4) Blanket : Non-tritium breeding blanket with test modules for breeding blanket development. 5) Magnets : Superconducting Magnets. (author)
Experimental evaluation of earthquake induced relay chattering
International Nuclear Information System (INIS)
Bandyopadhyay, K.; Hofmayer, C.; Shteyngart, S.
1990-01-01
An experimental evaluation of relay performance under vibratory environments is discussed in this paper. Single frequency excitation was used for most tests. Limited tests were performed with random multifrequency inputs. The capacity of each relay was established based on a two-millisecond chatter criterion. The experimental techniques are described and the effects of parameters in controlling the relay capacity levels are illustrated with test data. A wide variation of the capacity levels was observed due to the influence of parameters related to the design of the relay and nature of the input motion. 3 refs., 15 figs
Pogliani, Lionello
2010-01-30
Twelve properties of a highly heterogeneous class of organic solvents have been modeled with a graph-theoretical molecular connectivity modified (MC) method, which allows to encode the core electrons and the hydrogen atoms. The graph-theoretical method uses the concepts of simple, general, and complete graphs, where these last types of graphs are used to encode the core electrons. The hydrogen atoms have been encoded by the aid of a graph-theoretical perturbation parameter, which contributes to the definition of the valence delta, delta(v), a key parameter in molecular connectivity studies. The model of the twelve properties done with a stepwise search algorithm is always satisfactory, and it allows to check the influence of the hydrogen content of the solvent molecules on the choice of the type of descriptor. A similar argument holds for the influence of the halogen atoms on the type of core electron representation. In some cases the molar mass, and in a minor way, special "ad hoc" parameters have been used to improve the model. A very good model of the surface tension could be obtained by the aid of five experimental parameters. A mixed model method based on experimental parameters plus molecular connectivity indices achieved, instead, to consistently improve the model quality of five properties. To underline is the importance of the boiling point temperatures as descriptors in these last two model methodologies. Copyright 2009 Wiley Periodicals, Inc.
Directory of Open Access Journals (Sweden)
Ryan A. Shanks
2017-05-01
Full Text Available Introductory biology courses provide an important opportunity to prepare students for future courses, yet existing cookbook labs, although important in their own way, fail to provide many of the advantages of semester-long research experiences. Engaging, authentic research experiences aid biology students in meeting many learning goals. Therefore, overlaying a research experience onto the existing lab structure allows faculty to overcome barriers involving curricular change. Here we propose a working model for this overlay design in an introductory biology course and detail a means to conduct this lab with minimal increases in student and faculty workloads. Furthermore, we conducted exploratory factor analysis of the Experimental Design Ability Test (EDAT and uncovered two latent factors which provide valid means to assess this overlay model’s ability to increase advanced experimental design abilities. In a pre-test/post-test design, we demonstrate significant increases in both basic and advanced experimental design abilities in an experimental and comparison group. We measured significantly higher gains in advanced experimental design understanding in students in the experimental group. We believe this overlay model and EDAT factor analysis contribute a novel means to conduct and assess the effectiveness of authentic research experiences in an introductory course without major changes to the course curriculum and with minimal increases in faculty and student workloads.
Jia, Bing
2014-03-01
A comb-shaped chaotic region has been simulated in multiple two-dimensional parameter spaces using the Hindmarsh—Rose (HR) neuron model in many recent studies, which can interpret almost all of the previously simulated bifurcation processes with chaos in neural firing patterns. In the present paper, a comb-shaped chaotic region in a two-dimensional parameter space was reproduced, which presented different processes of period-adding bifurcations with chaos with changing one parameter and fixed the other parameter at different levels. In the biological experiments, different period-adding bifurcation scenarios with chaos by decreasing the extra-cellular calcium concentration were observed from some neural pacemakers at different levels of extra-cellular 4-aminopyridine concentration and from other pacemakers at different levels of extra-cellular caesium concentration. By using the nonlinear time series analysis method, the deterministic dynamics of the experimental chaotic firings were investigated. The period-adding bifurcations with chaos observed in the experiments resembled those simulated in the comb-shaped chaotic region using the HR model. The experimental results show that period-adding bifurcations with chaos are preserved in different two-dimensional parameter spaces, which provides evidence of the existence of the comb-shaped chaotic region and a demonstration of the simulation results in different two-dimensional parameter spaces in the HR neuron model. The results also present relationships between different firing patterns in two-dimensional parameter spaces.
International Nuclear Information System (INIS)
Jia Bing
2014-01-01
A comb-shaped chaotic region has been simulated in multiple two-dimensional parameter spaces using the Hindmarsh—Rose (HR) neuron model in many recent studies, which can interpret almost all of the previously simulated bifurcation processes with chaos in neural firing patterns. In the present paper, a comb-shaped chaotic region in a two-dimensional parameter space was reproduced, which presented different processes of period-adding bifurcations with chaos with changing one parameter and fixed the other parameter at different levels. In the biological experiments, different period-adding bifurcation scenarios with chaos by decreasing the extra-cellular calcium concentration were observed from some neural pacemakers at different levels of extra-cellular 4-aminopyridine concentration and from other pacemakers at different levels of extra-cellular caesium concentration. By using the nonlinear time series analysis method, the deterministic dynamics of the experimental chaotic firings were investigated. The period-adding bifurcations with chaos observed in the experiments resembled those simulated in the comb-shaped chaotic region using the HR model. The experimental results show that period-adding bifurcations with chaos are preserved in different two-dimensional parameter spaces, which provides evidence of the existence of the comb-shaped chaotic region and a demonstration of the simulation results in different two-dimensional parameter spaces in the HR neuron model. The results also present relationships between different firing patterns in two-dimensional parameter spaces
Influential parameters for designing and power consumption calculating of cumin mower
Energy Technology Data Exchange (ETDEWEB)
Mahmoodi, E.; Jafari, A. [Tehran Univ., Karaj (Iran, Islamic Republic of). Dept. of Agricultural Machinery Engineering
2010-07-01
This paper reported on a study in which the consuming power and design of cumin mowers was calculated. The parameters required for calculating power consumption and designing of cumin mowers were measured along with some engineering properties of cumin stems. These included shearing and bending tests on cumin stem and specifying the coefficient of friction between mower knives and cumin stem. The relationships between static and dynamic friction forces being exerted on mower runners by soil with normal load were determined along with the factor affecting soil moisture. Some of the other parameters that are important for calculating the power consumption and design of an optimized mower include harvest moisture content; maximum and average of cumin stem diameter; maximum bio-yield point of force and maximum ultimate point of force in the cutting; average energy required to cut a stem; maximum elasticity module; maximum bending rupture force; average energy required for bending a stem; friction coefficient between the stem and knife edge; relation between bio-yield force, failure force, elasticity and diameter in the cutting; relation between rupture forces and diameter in the bending; and mower weight.
Elayeb, O. K.; Alghoul, M. A.; Sopian, K.; Khrita, N. G.
2017-11-01
Despite Double skin façade (DSF) buildings are widely deployed worldwide, daylighting strategy is not commonly incorporated in these buildings compare to other strategies. Therefore, further theoretical and experimental studies would lead to adopting daylighting strategy in DSF office buildings. The aim of this study is to investigate the daylighting performance of office building at different design parameters of box window DSF using different glazing types under sub interval of intermediate sky conditions (20-40) klux using the (IES VE) simulation tool from Integrated Environmental Solutions - Virtual Environment. The implemented design parameters are window wall ratio (WWR) of internal façade (10-100) %, cavity depth (CD) of DSF (1-2.5) m and different glazing types. The glazing types were selected from the list available in the (IES VE) simulation tool. After series of evaluations, bronze tinted coating (STOPSOL) is implemented for the exterior façade while clear float, clear reflective coating (STOPSOL), grey and brown tinted coating (Anti-sun float) and blue coating tinted (SUNCOOL float) are implemented for the interior façade. In this paper, several evaluation parameters are used to quantify the optimum design parameters that would balance the daylighting requirements of a box window DSF office versus sky conditions range (20-40) klux. The optimum design parameters of DSF office building obtained under different glazing types are highlighted as follows. When using bronze tinted coating (STOPSOL) for the exterior façade, the glazing types of interior façade that showed superior daylighting performance of DSF office at (CD of 1.0m with WWR of 70%), (CD of 1.5m with WWR of 70%), (CD of 2.0m with WWR of 70%) and (CD of 2.0m with WWR of 70%) are grey tinted coating (Anti-sun float), clear reflective coating (STOPSOL), brown tinted coating (Anti-sun float), and clear float glazing respectively. Blue Coating tinted (SUNCOOL float) of interior façade glazing
SPHINX experimenters information package
International Nuclear Information System (INIS)
Zarick, T.A.
1996-08-01
This information package was prepared for both new and experienced users of the SPHINX (Short Pulse High Intensity Nanosecond X-radiator) flash X-Ray facility. It was compiled to help facilitate experiment design and preparation for both the experimenter(s) and the SPHINX operational staff. The major areas covered include: Recording Systems Capabilities,Recording System Cable Plant, Physical Dimensions of SPHINX and the SPHINX Test cell, SPHINX Operating Parameters and Modes, Dose Rate Map, Experiment Safety Approval Form, and a Feedback Questionnaire. This package will be updated as the SPHINX facilities and capabilities are enhanced
Design and experimental study of a solar system for heating water ...
African Journals Online (AJOL)
This work presents a design and an experimental study of a linear Fresnel reflector solar with trapezoidal cavity. This prototype is used for heating the tap water. The reflector was designed, constructed and tested in mechanical engineering department, University of Blida 1, Algeria. Various combinations of reflecting mirrors ...
Spillover effects in epidemiology: parameters, study designs and methodological considerations
Benjamin-Chung, Jade; Arnold, Benjamin F; Berger, David; Luby, Stephen P; Miguel, Edward; Colford Jr, John M; Hubbard, Alan E
2018-01-01
Abstract Many public health interventions provide benefits that extend beyond their direct recipients and impact people in close physical or social proximity who did not directly receive the intervention themselves. A classic example of this phenomenon is the herd protection provided by many vaccines. If these ‘spillover effects’ (i.e. ‘herd effects’) are present in the same direction as the effects on the intended recipients, studies that only estimate direct effects on recipients will likely underestimate the full public health benefits of the intervention. Causal inference assumptions for spillover parameters have been articulated in the vaccine literature, but many studies measuring spillovers of other types of public health interventions have not drawn upon that literature. In conjunction with a systematic review we conducted of spillovers of public health interventions delivered in low- and middle-income countries, we classified the most widely used spillover parameters reported in the empirical literature into a standard notation. General classes of spillover parameters include: cluster-level spillovers; spillovers conditional on treatment or outcome density, distance or the number of treated social network links; and vaccine efficacy parameters related to spillovers. We draw on high quality empirical examples to illustrate each of these parameters. We describe study designs to estimate spillovers and assumptions required to make causal inferences about spillovers. We aim to advance and encourage methods for spillover estimation and reporting by standardizing spillover parameter nomenclature and articulating the causal inference assumptions required to estimate spillovers. PMID:29106568
Three-dimensional FEM model of FBGs in PANDA fibers with experimentally determined model parameters
Lindner, Markus; Hopf, Barbara; Koch, Alexander W.; Roths, Johannes
2017-04-01
A 3D-FEM model has been developed to improve the understanding of multi-parameter sensing with Bragg gratings in attached or embedded polarization maintaining fibers. The material properties of the fiber, especially Young's modulus and Poisson's ratio of the fiber's stress applying parts, are crucial for accurate simulations, but are usually not provided by the manufacturers. A methodology is presented to determine the unknown parameters by using experimental characterizations of the fiber and iterative FEM simulations. The resulting 3D-Model is capable of describing the change in birefringence of the free fiber when exposed to longitudinal strain. In future studies the 3D-FEM model will be employed to study the interaction of PANDA fibers with the surrounding materials in which they are embedded.
Design parameters for a small storage ring optimized as an x-ray lithography source
International Nuclear Information System (INIS)
Grobman, W.D.
1983-01-01
This paper examines the design parameters for a ''compact storage ring'' which is matched well to x-ray lithographic requirements, but is as small as possible. This calculation uses a model of a lithographic system which obtains its input parameters from a technology of mask, resist and beam line based on the IBM program at the Brookhaven National Laboratory vacuum ultraviolet electron storage ring. Based on this lithographic system, we model exposure throughput as a function of storage ring parameters to understand which storage ring designs provide adequate but not excessive soft x-ray flux in the lithographically important region. Our scan of storage ring sources will cover a wide range of energies and magnetic fields, to permit consideration of superconducting as well as more standard strong- or weak-focusing designs. Furthermore, we will show that the results of the calculations presented here can be scaled in a simple way to cover a wide range of x-ray lithography system assumptions
Directory of Open Access Journals (Sweden)
Yun Zhang
2017-12-01
Full Text Available This paper mainly investigates the sensitive characteristics of lithium-ion batteries so as to provide scientific basises for simplifying the design of the state estimator that adapt to various environments. Three lithium-ion batteries are chosen as the experimental samples. The samples were tested at various temperatures (−20 ∘ C, −10 ∘ C, 0 ∘ C , 10 ∘ C , 25 ∘ C and various current rates (0.5C, 1C, 1.5C using a battery test bench. A physical equivalent circuit model is developed to capture the dynamic characteristics of the batteries. The experimental results show that all battery parameters are time-varying and have different sensitivity to temperature, current rate and state of charge (SOC. The sensitivity of battery to temperature, current rate and SOC increases the difficulty in battery modeling because of the change of parameters. The further simulation experiments show that the model output has a higher sensitivity to the change of ohmic resistance than that of other parameters. Based on the experimental and simulation results obtained here, it is expected that the adaptive parameter state estimator design could be simplified in the near future.
TIBER: Tokamak Ignition/Burn Experimental Research. Final design report
International Nuclear Information System (INIS)
Henning, C.D.; Logan, B.G.; Barr, W.L.
1985-01-01
The Tokamak Ignition/Burn Experimental Research (TIBER) device is the smallest superconductivity tokamak designed to date. In the design plasma shaping is used to achieve a high plasma beta. Neutron shielding is minimized to achieve the desired small device size, but the superconducting magnets must be shielded sufficiently to reduce the neutron heat load and the gamma-ray dose to various components of the device. Specifications of the plasma-shaping coil, the shielding, coaling, requirements, and heating modes are given. 61 refs., 92 figs., 30 tabs
A projection method for under determined optimal experimental designs
Long, Quan
2014-01-09
A new implementation, based on the Laplace approximation, was developed in (Long, Scavino, Tempone, & Wang 2013) to accelerate the estimation of the post–experimental expected information gains in the model parameters and predictive quantities of interest. A closed–form approximation of the inner integral and the order of the corresponding dominant error term were obtained in the cases where the parameters are determined by the experiment. In this work, we extend that method to the general cases where the model parameters could not be determined completely by the data from the proposed experiments. We carry out the Laplace approximations in the directions orthogonal to the null space of the corresponding Jacobian matrix, so that the information gain (Kullback–Leibler divergence) can be reduced to an integration against the marginal density of the transformed parameters which are not determined by the experiments. Furthermore, the expected information gain can be approximated by an integration over the prior, where the integrand is a function of the projected posterior covariance matrix. To deal with the issue of dimensionality in a complex problem, we use Monte Carlo sampling or sparse quadratures for the integration over the prior probability density function, depending on the regularity of the integrand function. We demonstrate the accuracy, efficiency and robustness of the proposed method via several nonlinear under determined numerical examples.
A projection method for under determined optimal experimental designs
Long, Quan; Scavino, Marco; Tempone, Raul; Wang, Suojin
2014-01-01
A new implementation, based on the Laplace approximation, was developed in (Long, Scavino, Tempone, & Wang 2013) to accelerate the estimation of the post–experimental expected information gains in the model parameters and predictive quantities of interest. A closed–form approximation of the inner integral and the order of the corresponding dominant error term were obtained in the cases where the parameters are determined by the experiment. In this work, we extend that method to the general cases where the model parameters could not be determined completely by the data from the proposed experiments. We carry out the Laplace approximations in the directions orthogonal to the null space of the corresponding Jacobian matrix, so that the information gain (Kullback–Leibler divergence) can be reduced to an integration against the marginal density of the transformed parameters which are not determined by the experiments. Furthermore, the expected information gain can be approximated by an integration over the prior, where the integrand is a function of the projected posterior covariance matrix. To deal with the issue of dimensionality in a complex problem, we use Monte Carlo sampling or sparse quadratures for the integration over the prior probability density function, depending on the regularity of the integrand function. We demonstrate the accuracy, efficiency and robustness of the proposed method via several nonlinear under determined numerical examples.
International Nuclear Information System (INIS)
Dubuc, J.P.; Azais, B.; Murcia, M. de
1994-01-01
This paper deals with experimental and simulation results on latch-up triggered by an electrical or X-rays pulse in CMOS/bulk devices. Test condition influences as well as the great importance of process parameters on latch-up immunity are emphasized. (author). 10 refs., 19 figs., 1 tab
Design and experimental results of the 1-T Bitter Electromagnet Testing Apparatus (BETA)
Bates, E. M.; Birmingham, W. J.; Romero-Talamás, C. A.
2018-05-01
The Bitter Electromagnet Testing Apparatus (BETA) is a 1-Tesla (T) technical prototype of the 10 T Adjustable Long Pulsed High-Field Apparatus. BETA's final design specifications are highlighted in this paper which include electromagnetic, thermal, and stress analyses. We discuss here the design and fabrication of BETA's core, vessel, cooling, and electrical subsystems. The electrical system of BETA is composed of a scalable solid-state DC breaker circuit. Experimental results display the stable operation of BETA at 1 T. These results are compared to both analytical design and finite element calculations. Experimental results validate analytical magnet designing methods developed at the Dusty Plasma Laboratory. The theoretical steady state maxima and the limits of BETA's design are explored in this paper.
Effect of fuel fabrication parameters on performance- designer's point of view
International Nuclear Information System (INIS)
Prasad, P.N.; Ravi, M.; Soni, R.; Bajaj, S.S.; Bhardwaj, S.A.
2004-01-01
The fuel bundle performance in reactor depends upon the material properties, dimensions of the different components and their inter-compatibility. This paper brings out the fuel parameters required to be optimised to achieve better fuel reliability, operational flexibility, safety and economics from the designer point of view
International Nuclear Information System (INIS)
Tian Daogui; Sun Licheng; Yan Changqi; Liu Guoqiang
2013-01-01
In order to get more local interfacial information as well as to further comprehend the intrinsic mechanism of two-phase flow under rolling condition, a method was proposed to measure the local parameters by using optical probes under rolling condition in this paper. An experimental investigation of two-phase flow under rolling condition was conducted using the probe fabricated by the authors. It is verified that the probe method is feasible to measure the local parameters in two'-phase flow under rolling condition. The results show that the interfacial parameters distribution near wall region has a distinct periodicity due to the rolling motion. The averaged deviation of the void fraction measured by the probe from that obtained from measured pressure drop is about 8%. (authors)
Experimental Device for Learning of Logical Circuit Design using Integrated Circuits
石橋, 孝昭
2012-01-01
This paper presents an experimental device for learning of logical circuit design using integrated circuits and breadboards. The experimental device can be made at a low cost and can be used for many subjects such as logical circuits, computer engineering, basic electricity, electrical circuits and electronic circuits. The proposed device is effective to learn the logical circuits than the usual lecture.
Evolutionary Design of Both Topologies and Parameters of a Hybrid Dynamical System
DEFF Research Database (Denmark)
Dupuis, Jean-Francois; Fan, Zhun; Goodman, Erik
2012-01-01
This paper investigates the issue of evolutionary design of open-ended plants for hybrid dynamical systems--i.e. both their topologies and parameters. Hybrid bond graphs are used to represent dynamical systems involving both continuous and discrete system dynamics. Genetic programming, with some...... of hybrid dynamical systems that fulfill predefined design specifications. A comprehensive investigation of a case study of DC-DC converter design demonstrates the feasibility and effectiveness of the HBGGP approach. Important characteristics of the approach are also discussed, with some future research...
Design study of blanket structure for tokamak experimental fusion reactor
International Nuclear Information System (INIS)
1979-11-01
Design study of the blanket structure for JAERI Experimental Fusion Reactor (JXFR) has been carried out. Studied here were fabrication and testing of the blanket structure (blanket cells, blanket rings, piping and blanket modules), assembly and disassembly of the blanket module, and monitering and testing technique. Problems in design and fabrication of the blanket structure could be revealed. Research and development problems for the future were also disclosed. (author)
Energy Technology Data Exchange (ETDEWEB)
Le Duy Cuong; Duong, Thanh Hung; Kim, Huyn Chul [Inje University, Gimhae (Korea, Republic of)
2014-05-15
Micro/nano-scale tungsten tips fabricated by electrochemical etching have many diverse industrial applications. The characteristic parameters of the tungsten tip profile include apex radius, taper angle, and aspect ratio. These parameters are governed by many factors including applied voltage, concentration of the electrolyte (potassium hydroxide) solution, and diameter of the inner gold ring. However, a systematic investigation with the aim of determining the best conditions for fabricating micro/nano-scale tips with desired profiles has not been carried out yet. This study is aimed at obtaining controllable tungsten tip -particularly with respect to the radius of curvature and aspect ratio of tips (taper angle)-by altering the experimental conditions. A series of experiments were executed and the results were aggregated and analyzed using response surface methodology in order to identify the relationships between the tungsten tip characteristics and input parameters. The method proposed herein would prove to be suitable for a variety of applications in industries that require tungsten tips with a specific profile.
International Nuclear Information System (INIS)
Le Duy Cuong; Duong, Thanh Hung; Kim, Huyn Chul
2014-01-01
Micro/nano-scale tungsten tips fabricated by electrochemical etching have many diverse industrial applications. The characteristic parameters of the tungsten tip profile include apex radius, taper angle, and aspect ratio. These parameters are governed by many factors including applied voltage, concentration of the electrolyte (potassium hydroxide) solution, and diameter of the inner gold ring. However, a systematic investigation with the aim of determining the best conditions for fabricating micro/nano-scale tips with desired profiles has not been carried out yet. This study is aimed at obtaining controllable tungsten tip -particularly with respect to the radius of curvature and aspect ratio of tips (taper angle)-by altering the experimental conditions. A series of experiments were executed and the results were aggregated and analyzed using response surface methodology in order to identify the relationships between the tungsten tip characteristics and input parameters. The method proposed herein would prove to be suitable for a variety of applications in industries that require tungsten tips with a specific profile
Si, Ting; Zhang, Leilei; Li, Guangbin; Roberts, Cynthia J; Yin, Xiezhen; Xu, Ronald
2013-07-01
Recent developments in multimodal imaging and image-guided therapy requires multilayered microparticles that encapsulate several imaging and therapeutic agents in the same carrier. However, commonly used microencapsulation processes have multiple limitations such as low encapsulation efficiency and loss of bioactivity for the encapsulated biological cargos. To overcome these limitations, we have carried out both experimental and theoretical studies on coaxial electrospray of multilayered microparticles. On the experimental side, an improved coaxial electrospray setup has been developed. A customized coaxial needle assembly combined with two ring electrodes has been used to enhance the stability of the cone and widen the process parameter range of the stable cone-jet mode. With this assembly, we have obtained poly(lactide-co-glycolide) microparticles with fine morphology and uniform size distribution. On the theoretical side, an instability analysis of the coaxial electrified jet has been performed based on the experimental parameters. The effects of process parameters on the formation of different unstable modes have been studied. The reported experimental and theoretical research represents a significant step toward quantitative control and optimization of the coaxial electrospray process for microencapsulation of multiple drugs and imaging agents in multimodal imaging and image-guided therapy.
Design parameters and source terms: Volume 3, Source terms: Revision 0
International Nuclear Information System (INIS)
1987-09-01
The Design Parameters and Source Terms Document was prepared in accordance with DOE request and to provide data for the environmental impact study to be performed in the future for the Deaf Smith County, Texas site for a nuclear waste repository in salt. This document updates a previous unpublished report to the level of the Site Characterization Plan /endash/ Conceptual Design Report, SCP-CDR. The previous unpublished SCC Study identifies the data needs for the Environmental Assessment effort for seven possible salt repository sites
Selected parameters of moulding sands for designing quality control systems
Directory of Open Access Journals (Sweden)
J. Jakubski
2010-07-01
Full Text Available One of the modern methods of production optimisation are artificial neural networks. Neural networks owe their popularity to the fact thatthey are convenient tools, which can be utilised in a wide scope of problems. They are capable of reflecting complex functions. Especiallytheir non-linearity should be emphasised. They are gaining wider and wider application in the foundry industry, among others, to controlmelting processes in cupolas and arc furnaces, designing castings and supply systems, control of moulding sands treatments, prediction ofproperties of cast alloys as well as selecting die casting.An attempt of the application neural networks to the quality control of moulding sands with bentonite is presented in the paper. This isa method of assessing the suitability of moulding sands by finding correlations in between individual parameters, by means of artificialneural network systems. The presented investigations were performed with the application of the Statistica 8.0 program.The investigations were aimed at the selection of the proper kind of a neural network for prediction a sand moistness on the bases ofcertain moulding sand properties such as: permeability, compactibility and friability. These parameters – determined as sand moistness functions - were introduced as initial parameters.Application of the Statistica program allowed for an automatic selection of the most suitable network for the reflection of dependencies and interactions existing among the proposed parameters. The best results were obtained for unidirectional multi-layer perception network (MLP. The neural network sensitivity to individual moulding sand parameters was determined, which allowed to reject not important parameters when constructing the network.
Design of Passive Acoustic Wave Shaping Devices and Their Experimental Validation
DEFF Research Database (Denmark)
Christiansen, Rasmus Ellebæk; Sigmund, Ole; Fernandez Grande, Efren
We discuss a topology optimization based approach for designing passive acoustic wave shaping devices and demonstrate its application to; directional sound emission [1], sound focusing and wave splitting. Optimized devices, numerical and experimental results are presented and benchmarked against...... other designs proposed in the literature. We focus on design problems where the size of the device is on the order of the wavelength, a problematic region for traditional design methods, such as ray tracing.The acoustic optimization problem is formulated in the frequency domain and modeled...
Optimal Design of Measurement Programs for the Parameter Identification of Dynamic Systems
DEFF Research Database (Denmark)
Kirkegaard, Poul Henning; Sørensen, John Dalsgaard; Brincker, Rune
The design of measurement programs devoted to parameter identification of structural dynamic systems is considered. The design problem is formulated as an optimization problem to minimize the total expected cost that is the cost of failure and the cost of the measurement program. All...... the calculations are based on a priori knowledge and engineering judgement. One of the contribution of the approach is that the optimal number of sensors can be estimated. This is shown in a numerical example where the proposed approach is demonstrated. The example is concerned with design of a measurement program...
Optimal Design of Measurement Programs for the Parameter Identification of Dynamic Systems
DEFF Research Database (Denmark)
Kirkegaard, Poul Henning; Sørensen, John Dalsgaard; Brincker, Rune
1993-01-01
The design of a measurement program devoted to parameter identification of structural dynamic systems is considered. The design problem is formulated as an optimization problem to minimize the total expected cost that is the cost of failure and the cost of the measurement program. All...... the calculations are based on a priori knowledge and engineering judgement. One of the contribution of the approach is that the optimal number of sensory can be estimated. This is shown in an numerical example where the proposed approach is demonstrated. The example is concerned with design of a measurement...
Optimal Design of Measurement Programs for the Parameter Identification of Dynamic Systems
DEFF Research Database (Denmark)
Kirkegaard, Poul Henning; Sørensen, John Dalsgaard; Brincker, Rune
1991-01-01
The design of a measurement program devoted to parameter identification of structural dynamic systems is considered. The design problem is formulated as an optimization problem to minimize the total expected cost, i.e. the cost of failure and the cost of the measurement program. All...... the calculations are based on a priori knowledge and engineering judgement. One of the contributions of the approach is that the optimal number of sensors can be estimated. This is shown in a numerical example where the proposed approach is demonstrated. The example is concerned with design of a measurement...
Experimental concept and design of DarkLight, a search for a heavy photon
International Nuclear Information System (INIS)
Cowan, Ray F.
2013-01-01
This talk gives an overview of the DarkLight experimental concept: a search for a heavy photon A′ in the 10-90 MeV/c 2 mass range. After briefly describing the theoretical motivation, the talk focuses on the experimental concept and design. Topics include operation using a half-megawatt, 100 MeV electron beam at the Jefferson Lab FEL, detector design and performance, and expected backgrounds estimated from beam tests and Monte Carlo simulations
Training reactor deployment. Advanced experimental course on designing new reactor cores
International Nuclear Information System (INIS)
Skoda, Radek
2009-01-01
Czech Technical University in Prague (CTU) operating its training nuclear reactor VR1, in cooperation with the North West University of South Africa (NWU), is applying for accreditation of the experimental training course ''Advanced experimental course on designing the new reactor core'' that will guide the students, young nuclear engineering professionals, through designing, calculating, approval, and assembling a new nuclear reactor core. Students, young professionals from the South African nuclear industry, face the situation when a new nuclear reactor core is to be build from scratch. Several reactor core design options are pre-calculated. The selected design is re-calculated by the students, the result is then scrutinized by the regulator and, once all the analysis is approved, physical dismantling of the current core and assembling of the new core is done by the students, under a close supervision of the CTU staff. Finally the reactor is made critical with the new core. The presentation focuses on practical issues of such a course, desired reactor features and namely pedagogical and safety aspects. (orig.)
Activation method for measurement of neutron spectrum parameters
International Nuclear Information System (INIS)
Efimov, B.V.; Demidov, A.M.; Ionov, V.S.; Konjaev, S.I.; Marin, S.V.; Bryzgalov, V.I.
2007-01-01
Experimental researches of spectrum parameters of neutrons at nuclear installations RRC KI are submitted. The installations have different designs of the cores, reflector, parameters and types of fuel elements. Measurements were carried out with use of the technique developed in RRC KI for irradiation resonance detectors UKD. The arrangement of detectors in the cores ensured possibility of measurement of neutron spectra with distinguished values of parameters. The spectrum parameters which are introduced by parametrical representation of a neutrons spectrum in the form corresponding to formalism Westcott. On experimental data were determinate absolute values of density neutron flux (DNF) in thermal and epithermal area of a spectrum (F t , f epi ), empirical dependence of temperature of neutron gas (Tn) on parameter of a rigidity of a spectrum (z), density neutron flux in transitional energy area of the spectrum. Dependences of spectral indexes of nuclides (UDy/UX), included in UKD, from a rigidity z and-or temperatures of neutron gas Tn are obtained.B Tools of mathematical processing of results are used for activation data and estimation of parameters of a spectrum (F t , f epi , z, Tn, UDy/UX). In the paper are presented some results of researches of neutron spectrum parameters of the nuclear installations (Authors)
Ghosal, Partha S; Gupta, Ashok K; Sulaiman, Ayoob
2016-01-01
Response surface methodology was applied for the first time in the optimization of the preparation of layered double hydroxide (LDH) for defluoridation. The influence of three vital process parameters (viz. pH, molar ratio and calcination temperature) in the synthesis of the adsorbent 'Calcined Ca‒Al (NO3) LDH' was thoroughly examined to maximize its fluoride scavenging potential. The process parameters were optimized using the 3(3) factorial, face centered central composite and Box-Behnken designs and a comparative assessment of the methods was conducted. The maximum fluoride removal efficiency was achieved at a calcination temperature of approximately 500ºC; however, the efficiency decreased with increasing pH and molar ratio. The outcome of the comparative assessment clearly delineates the case specific nature of the models. A better predictability over the entire experimental domain was obtained with the 3(3) factorial method, whereas the Box-Behnken design was found to be the most efficient model with lesser number of experimental runs. The desirability function technique was performed for optimizing the response, wherein face centered central composite design exhibited a maximum desirability. The calcined Ca‒Al (NO3) LDH, synthesized under the optimum conditions, demonstrated the removal efficiencies of 95% and 99% for the doses of 3 g L(-1) and 5 g L(-1), respectively.
Experimental Study on Abrasive Waterjet Polishing of Hydraulic Turbine Blades
International Nuclear Information System (INIS)
Khakpour, H; Birglenl, L; Tahan, A; Paquet, F
2014-01-01
In this paper, an experimental investigation is implemented on the abrasive waterjet polishing technique to evaluate its capability in polishing of surfaces and edges of hydraulic turbine blades. For this, the properties of this method are studied and the main parameters affecting its performance are determined. Then, an experimental test-rig is designed, manufactured and tested to be used in this study. This test-rig can be used to polish linear and planar areas on the surface of the desired workpieces. Considering the number of parameters and their levels, the Taguchi method is used to design the preliminary experiments. All experiments are then implemented according to the Taguchi L 18 orthogonal array. The signal-to-noise ratios obtained from the results of these experiments are used to determine the importance of the controlled polishing parameters on the final quality of the polished surface. The evaluations on these ratios reveal that the nozzle angle and the nozzle diameter have the most important impact on the results. The outcomes of these experiments can be used as a basis to design a more precise set of experiments in which the optimal values of each parameter can be estimated
Design and Implementation of an Experimental Cataloging Advisor--Mapper.
Ercegovac, Zorana; Borko, Harold
1992-01-01
Describes the design of an experimental computer-aided cataloging advisor, Mapper, that was developed to help novice users with the descriptive cataloging of single-sheet maps from U.S. publishers. The human-computer interface is considered, the use of HyperCard is discussed, the knowledge base is explained, and assistance screens are described.…
International Nuclear Information System (INIS)
Vasiliev, A.; Alekseev, P.; Mikityuk, K.; Fomichenko, P.; Shestopalov, A.
2002-01-01
Development of advanced reactors with innovative materials requires comprehensive analysis of fuel rod design parameters as well as tolerances to be imposed on these parameters. Currently, it is considered traditional to estimate uncertainties in core neutronics parameters on the basis of known tolerances imposed on fuel rod design parameters. However, requirements to some core neutronics parameters of advanced reactors can be first formulated and then taken into account, while developing the technologies for innovative fuel rod manufacturing, i.e. an 'inverse' problem can be solved. The aim of this problem is to find combinations of fuel rod design tolerances which provide that selected core neutronics parameters remain within specified deviations during base irradiation. (authors)
Design parameters and source terms: Volume 2, Source terms: Revision 0
International Nuclear Information System (INIS)
1987-09-01
The Design Parameters and Source Terms Document was prepared in accordance with DOE request and to provide data for the environmental impact study to be performed in the future for the Deaf Smith County, Texas site for a nuclear waste repository in salt. This document updates a previous unpublished report to the level of the Site Characterization Plan---Conceptual Design Report SCP-CDR. The previous study identifies the data needs for the Environmental Assessment effort for seven possible salt repository sites. Volume 2 contains tables of source terms
Energy Technology Data Exchange (ETDEWEB)
Ducret, D.; Vendel, J.; Garrec. S.L.
1995-02-01
The safety of a nuclear power plant containment building, in which pressure and temperature could increase because of a overheating reactor accident, can be achieved by spraying water drops. The spray reduces the pressure and the temperature levels by condensation of steam on cold water drops. The more stringent thermodynamic conditions are a pressure of 5.10{sup 5} Pa (due to steam emission) and a temperature of 413 K. Moreover its energy dissipation function, the spray leads to the washout of fission product particles emitted in the reactor building atmosphere. The present study includes a large program devoted to the evaluation of realistic washout rates. The aim of this work is to develop experiments in order to determine the collection efficiency of aerosols by a single drop. To do this, the experimental device has to be designed with fundamental criteria:-Thermodynamic conditions have to be representative of post-accident atmosphere. Thermodynamic equilibrium has to be attained between the water drops and the gaseous phase. Thermophoretic, diffusiophoretic and mechanical effects have to be studied independently. Operating conditions have to be homogenous and constant during each experiment. This paper presents the design of the experimental device. In practice, the consequences on the design of each of the criteria given previously and the necessity of being representative of the real conditions will be described.
Ndoye, Ibrahima; Voos, Holger; Laleg-Kirati, Taous-Meriem; Darouach, Mohamed
2014-01-01
In this paper, an adaptive observer design with parameter identification for a nonlinear system with external perturbations and unknown parameters is proposed. The states of the nonlinear system are estimated by a nonlinear observer and the unknown
DEFF Research Database (Denmark)
Clausen, Niels Christian Jerichau; Arslanagic, Samel; Breinbjerg, Olav
2012-01-01
A 1D dielectric finite Bragg stack situated in a rectangular waveguide and illuminated by the fundamental TE10 mode is examined analytically, numerically, and experimentally. Calculated as well as measured scattering parameters are used to extract the effective/equivalent material parameters...... for three specific configurations of its constituent unit cell. Particular attention is devoted to the absence/presence of certain oscillations in the extracted material parameters, depending on the unit cell configuration. The results for the finite Bragg stack are further verified to agree with those...... of an infinite Bragg stack, for which the dispersion equation is used in conjunction with the Floquet-Bloch harmonics expansion to extract the material parameters. It is shown that the extracted material parameters for the finite and infinite Bragg stacks agree for the symmetric unit cell configuration....
Reverse design and characteristic study of multi-range HMCVT
Zhu, Zhen; Chen, Long; Zeng, Falin
2017-09-01
The reduction of fuel consumption and increase of transmission efficiency is one of the key problems of the agricultural machinery. Many promising technologies such as hydromechanical continuously variable transmissions (HMCVT) are the focus of research and investments, but there is little technical documentation that describes the design principle and presents the design parameters. This paper presents the design idea and characteristic study of HMCVT, in order to find out the suitable scheme for the big horsepower tractors. Analyzed the kinematics and dynamics of a large horsepower tractor, according to the characteristic parameters, a hydro-mechanical continuously variable transmission has been designed. Compared with the experimental curves and theoretical curves of the stepless speed regulation of transmission, the experimental result illustrates the rationality of the design scheme.
Evaluation of Experimental Parameters in the Accelerated Aging of Closed-Cell Foam Insulation
Energy Technology Data Exchange (ETDEWEB)
Stovall, Therese K [ORNL; Vanderlan, Michael [ORNL; Atchley, Jerald Allen [ORNL
2012-12-01
The thermal conductivity of many closed-cell foam insulation products changes over time as production gases diffuse out of the cell matrix and atmospheric gases diffuse into the cells. Thin slicing has been shown to be an effective means of accelerating this process in such a way as to produce meaningful results. Efforts to produce a more prescriptive version of the ASTM C1303 standard test method led to the ruggedness test described here. This test program included the aging of full size insulation specimens for time periods of five years for direct comparison to the predicted results. Experimental parameters under investigation include: slice thickness, slice origin (at the surface or from the core of the slab), thin slice stack composition, product facings, original product thickness, product density, and product type. The test protocol has been completed and this report provides a detailed evaluation of the impact of the test parameters on the accuracy of the 5-year thermal conductivity prediction.
Parameters design of the dielectric elastomer spring-roll bending actuator (Conference Presentation)
Li, Jinrong; Liu, Liwu; Liu, Yanju; Leng, Jinsong
2017-04-01
Dielectric elastomers are novel soft smart material that could deform sustainably when subjected to external electric field. That makes dielectric elastomers promising materials for actuators. In this paper, a spring-roll actuator that would bend when a high voltage is applied was fabricated based on dielectric elastomer. Using such actuators as active parts, the flexible grippers and inchworm-inspired crawling robots were manufactured, which demonstrated some examples of applications in soft robotics. To guide the parameters design of dielectric elastomer based spring-roll bending actuators, the theoretical model of such actuators was established based on thermodynamic theories. The initial deformation and electrical induced bending angle of actuators were formulated. The failure of actuators was also analyzed considering some typical failure modes like electromechanical instability, electrical breakdown, loss of tension and maximum tolerant stretch. Thus the allowable region of actuators was determined. Then the bending angle-voltage relations and failure voltages of actuators with different parameters, including stretches of the dielectric elastomer film, number of active layers, and dimensions of spring, were investigated. The influences of each parameter on the actuator performances were discussed, providing meaningful guidance to the optical design of the spring-roll bending actuators.
Caiazzo, A; Caforio, Federica; Montecinos, Gino; Muller, Lucas O; Blanco, Pablo J; Toro, Eluterio F
2016-10-25
This work presents a detailed investigation of a parameter estimation approach on the basis of the reduced-order unscented Kalman filter (ROUKF) in the context of 1-dimensional blood flow models. In particular, the main aims of this study are (1) to investigate the effects of using real measurements versus synthetic data for the estimation procedure (i.e., numerical results of the same in silico model, perturbed with noise) and (2) to identify potential difficulties and limitations of the approach in clinically realistic applications to assess the applicability of the filter to such setups. For these purposes, the present numerical study is based on a recently published in vitro model of the arterial network, for which experimental flow and pressure measurements are available at few selected locations. To mimic clinically relevant situations, we focus on the estimation of terminal resistances and arterial wall parameters related to vessel mechanics (Young's modulus and wall thickness) using few experimental observations (at most a single pressure or flow measurement per vessel). In all cases, we first perform a theoretical identifiability analysis on the basis of the generalized sensitivity function, comparing then the results owith the ROUKF, using either synthetic or experimental data, to results obtained using reference parameters and to available measurements. Copyright © 2016 John Wiley & Sons, Ltd.
Design study of a neutral beam injection system for the JAERI Experimental Fusion Reactor (JXFR)
International Nuclear Information System (INIS)
1977-10-01
Design study has been made of a 200 kV, 45 MW D 0 neutral beam injection system for the JAERI Experimental Fusion Reactor (JXFR) covering the following: determination of the ion source specifications, design of components such as ion source with extraction electrodes, energy converter, cryopump and cooling system, and estimations of the energy conversion efficiency, overall power efficiency and total power required for operation of the NBI system, and also a hydrogen isotope separation method using cryo-sorption pumps. Optimizations and parameter studies of the neutralizing cell length, gas flow rate, operating pressure of ion sources, total pumping speed and pressure of energy converters are made in the design study based on reactor plasma requirements. Hollow cathode ion sources are proposed because of the extended operation time at low gas pressure (about 4.5 x 10 -3 Torr) and the high gas efficiency (40%). Life of the extraction electrodes is determined by blistering due to deuterium ions. Fast neutron radiation damage is relatively small. In-line direct converters with grounded recovery electrodes and neutralizing cells floated at negative potential -190 kV are used to recover residual deuterium ion energy without interrupting the neutral beam trajectories. Energy conversion efficiency of 80% and overall power efficiency of about 40% are obtained. (auth.)
Strategy of experimental studies in PNC on natural convection decay heat removal
International Nuclear Information System (INIS)
Ieda, Y.; Kamide, H.; Ohshima, H.; Sugawara, S.; Ninokata, H.
1993-01-01
Experimental studies have been and are being carried out in PNC to establish the design and safety evaluation methods and the design and safety evaluation guide lines for decay heat removal by natural convection. A strategy of the experimental studies in PNC is described in this paper. The sphere of studies in PNC is to develop the evaluation methods to be available to DRACS as well as PRACS and IRACS for the plant where decay heat is removed by natural convection in some cases of loss of station service power. Similarity parameters related to natural convection are derived from the governing equations. The roles of both sodium and water experiments are defined in consideration of the importance of the similarity parameters and characteristics of scale model experiments. The experimental studies in PNC are reviewed. On the basis of the experimental results, recommended evaluation methods are shown for decay heat removal feature by natural convection. Future experimental works are also proposed. (author)
Spent Fuel Transportation Package Performance Study - Experimental Design Challenges
International Nuclear Information System (INIS)
Snyder, A. M.; Murphy, A. J.; Sprung, J. L.; Ammerman, D. J.; Lopez, C.
2003-01-01
Numerous studies of spent nuclear fuel transportation accident risks have been performed since the late seventies that considered shipping container design and performance. Based in part on these studies, NRC has concluded that the level of protection provided by spent nuclear fuel transportation package designs under accident conditions is adequate. [1] Furthermore, actual spent nuclear fuel transport experience showcase a safety record that is exceptional and unparalleled when compared to other hazardous materials transportation shipments. There has never been a known or suspected release of the radioactive contents from an NRC-certified spent nuclear fuel cask as a result of a transportation accident. In 1999 the United States Nuclear Regulatory Commission (NRC) initiated a study, the Package Performance Study, to demonstrate the performance of spent fuel and spent fuel packages during severe transportation accidents. NRC is not studying or testing its current regulations, a s the rigorous regulatory accident conditions specified in 10 CFR Part 71 are adequate to ensure safe packaging and use. As part of this study, NRC currently plans on using detailed modeling followed by experimental testing to increase public confidence in the safety of spent nuclear fuel shipments. One of the aspects of this confirmatory research study is the commitment to solicit and consider public comment during the scoping phase and experimental design planning phase of this research
Publishing Single-Case Research Design Studies That Do Not Demonstrate Experimental Control
Tincani, Matt; Travers, Jason
2018-01-01
Demonstration of experimental control is considered a hallmark of high-quality single-case research design (SCRD). Studies that fail to demonstrate experimental control may not be published because researchers are unwilling to submit these papers for publication and journals are unlikely to publish negative results (i.e., the file drawer effect).…
Self-adaptive Green-Ampt infiltration parameters obtained from measured moisture processes
Directory of Open Access Journals (Sweden)
Long Xiang
2016-07-01
Full Text Available The Green-Ampt (G-A infiltration model (i.e., the G-A model is often used to characterize the infiltration process in hydrology. The parameters of the G-A model are critical in applications for the prediction of infiltration and associated rainfall-runoff processes. Previous approaches to determining the G-A parameters have depended on pedotransfer functions (PTFs or estimates from experimental results, usually without providing optimum values. In this study, rainfall simulators with soil moisture measurements were used to generate rainfall in various experimental plots. Observed runoff data and soil moisture dynamic data were jointly used to yield the infiltration processes, and an improved self-adaptive method was used to optimize the G-A parameters for various types of soil under different rainfall conditions. The two G-A parameters, i.e., the effective hydraulic conductivity and the effective capillary drive at the wetting front, were determined simultaneously to describe the relationships between rainfall, runoff, and infiltration processes. Through a designed experiment, the method for determining the G-A parameters was proved to be reliable in reflecting the effects of pedologic background in G-A type infiltration cases and deriving the optimum G-A parameters. Unlike PTF methods, this approach estimates the G-A parameters directly from infiltration curves obtained from rainfall simulation experiments so that it can be used to determine site-specific parameters. This study provides a self-adaptive method of optimizing the G-A parameters through designed field experiments. The parameters derived from field-measured rainfall-infiltration processes are more reliable and applicable to hydrological models.
Experimental use of iteratively designed rotation invariant correlation filters
International Nuclear Information System (INIS)
Sweeney, D.W.; Ochoa, E.; Schils, G.F.
1987-01-01
Iteratively designed filters are incorporated into an optical correlator for position, rotation, and intensity invariant recognition of target images. The filters exhibit excellent discrimination because they are designed to contain full information about the target image. Numerical simulations and experiments demonstrate detection of targets that are corrupted with random noise (SNR≅0.5) and also partially obscured by other objects. The complex valued filters are encoded in a computer generated hologram and fabricated directly using an electron-beam system. Experimental results using a liquid crystal spatial light modulator for real-time input show excellent agreement with analytical and numerical computations
Energy Technology Data Exchange (ETDEWEB)
Arca, S.; Di Profio, P.; Germani, R.; Savelli, G. [Perugia Univ., CEMIN, Perugia (Italy). Dept. of Chemistry
2008-07-01
There is a growing interest in understanding the thermodynamics and kinetics of clathrate hydrate formation. This paper presented a study that involved the design, construction, calibration, and testing of a new apparatus that could obtain as many parameters as possible in a single formation batch and that could measure unexplored clathrate hydrate parameters. The apparatus was capable of measuring equilibrium phases involving gaseous components. The paper described the conceptual design as well as the chamber, pressure line, temperature control, liquid addition line, and conductometric probe. The paper also discussed data acquisition, stirring, measurement examples, and internal illumination and video monitoring. It was concluded that refining measurements, particularly those concerning kinetic characterizations, is important in order to clarify several uncertain kinetic behaviors of clathrate hydrates. 6 refs., 16 figs.
Design and implementation of a S-parameter wafer defect scanner
International Nuclear Information System (INIS)
Naik, P.S.; Beling, C.D.; Fung, S.
2004-01-01
We describe the design and implementation of a real-time automated scanning system that gives an S-parameter image of a semiconductor wafer, thus allowing the density of vacancy type defects to be shown as a function of position on the wafer. A conventional 22 Na positron source of 0.5 mm diameter rasters across 5 x 5 cm 2 region of two times per hour in rectilinear motion. Gamma ray energies E γ are processed using a standard HP Ge spectroscopy system and a 14 bit nuclear ADC. Over a period of 1-2 days a high resolution 128 x 128 pixel image with 256 colours (scaled to the S-parameter range) can be formed as a wafer defect map. The system is reliable, interactive and user-friendly (patent pending 2003). (orig.)
Reference design (MK-I and MK-II) for experimental multi-purpose VHTR
International Nuclear Information System (INIS)
Miyamoto, Yoshiaki; Suzuki, Kunihiko; Sato, Sadao
1975-10-01
This report summarizes the results of a study on thermal and mechanical performances of the core, which are obtained in course of reference design (Mk-I and Mk-II) for the experimental multi-purpose VHTR: (1) Design criteria, design methods and design data. These bases are also discussed in order to refer in the case of proceeding a next design work. (2) The results of performance analysis such as the initial core and its prediction for the irradiated core. (auth.)
Experimental study of liquid-metal target designs of accelerating-controlled systems
International Nuclear Information System (INIS)
Iarmonov, Mikhail; Makhov, Kirill; Novozhilova, Olga; Meluzov, A.G.; Beznosov, A.V.
2011-01-01
Models of a liquid-metal target of an accelerator-controlled system have been experimentally studied at the Nizhny Novgorod State Technical University to develop an optimal design of the flow part of the target. The main explored variants of liquid-metal targets are: Design with a diaphragm (firm-and-impervious plug) mounted on the pipe tap of particle transport from the accelerator cavity to the working cavity of the liquid-metal target. Design without a diaphragm on the pipe tab of particle transport from the accelerator. The study was carried out in a high-temperature liquid-metal test bench under the conditions close to full-scale ones: the temperature of the eutectic lead-bismuth alloy was 260degC - 400degC, the coolant mass flow was 5-80 t/h, and the rarefaction in the gas cavity was 10 5 Pa, the coefficient of geometric similarity equal to 1. The experimental studies of hydrodynamic characteristics of flow parts in the designs of targets under full-scale conditions indicated high efficiency of a target in triggering, operating, and deactivating modes. Research and technology instructions for designs of the flow part of the liquid-metal target, the target design as a whole, and the target circuit of accelerator-controlled systems were formulated as a result of the studies. (author)
International Nuclear Information System (INIS)
Milovanski, Vasil; , Blagoevgrad (Bulgaria))" data-affiliation=" (HMS “Acad. S. P. Corolov, Blagoevgrad (Bulgaria))" >Stoyanov, Krasimir; Milovanska, Stefani
2013-01-01
Some opportunities for development of an experimental module for magnetic research have been examined in the current paper. The goal is to attain a more accurate reading of the measured electrical signals which are directly related to the magnetic parameters and characteristics of the ferromagnetic material
Bayesian Parameter Estimation for Heavy-Duty Vehicles
Energy Technology Data Exchange (ETDEWEB)
Miller, Eric; Konan, Arnaud; Duran, Adam
2017-03-28
Accurate vehicle parameters are valuable for design, modeling, and reporting. Estimating vehicle parameters can be a very time-consuming process requiring tightly-controlled experimentation. This work describes a method to estimate vehicle parameters such as mass, coefficient of drag/frontal area, and rolling resistance using data logged during standard vehicle operation. The method uses Monte Carlo to generate parameter sets which is fed to a variant of the road load equation. Modeled road load is then compared to measured load to evaluate the probability of the parameter set. Acceptance of a proposed parameter set is determined using the probability ratio to the current state, so that the chain history will give a distribution of parameter sets. Compared to a single value, a distribution of possible values provides information on the quality of estimates and the range of possible parameter values. The method is demonstrated by estimating dynamometer parameters. Results confirm the method's ability to estimate reasonable parameter sets, and indicates an opportunity to increase the certainty of estimates through careful selection or generation of the test drive cycle.
International Nuclear Information System (INIS)
Bernreuter, D.L.
1977-08-01
One of the most important steps in the seismic design process is the specification of the appropriate ground motion to be input into the design analysis. From the point-of-view of engineering design analysis, the important parameters are peak ground acceleration, spectral shape and peak spectral levels. In a few cases, ground displacement is a useful parameter. The earthquake is usually specified by giving its magnitude and either the epicentral distance or the distance of the closest point on the causitive fault to the site. Typically, the appropriate ground motion parameters are obtained using the specified magnitude and distance in equations obtained from regression analysis among the appropriate variables. Two major difficulties with such an approach are: magnitude is not the best parameter to use to define the strength of an earthquake, and little near-field data is available to establish the appropriate form for the attenuation of the ground motion with distance, source size and strength. These difficulties are important for designing a critical facility; i.e., one for which a very low risk of exceeding the design ground motion is required. Examples of such structures are nuclear power plants, schools and hospitals. for such facilities, a better understanding of the relation between the ground motion and the important earthquake source parameters could be very useful for several reasons
Amjad, M.; Salam, Z.; Ishaque, K.
2014-04-01
In order to design an efficient resonant power supply for ozone gas generator, it is necessary to accurately determine the parameters of the ozone chamber. In the conventional method, the information from Lissajous plot is used to estimate the values of these parameters. However, the experimental setup for this purpose can only predict the parameters at one operating frequency and there is no guarantee that it results in the highest ozone gas yield. This paper proposes a new approach to determine the parameters using a search and optimization technique known as Differential Evolution (DE). The desired objective function of DE is set at the resonance condition and the chamber parameter values can be searched regardless of experimental constraints. The chamber parameters obtained from the DE technique are validated by experiment.
Selection of a design for response surface
Ranade, Shruti Sunil; Thiagarajan, Padma
2017-11-01
Box-Behnken, Central-Composite, D and I-optimal designs were compared using statistical tools. Experimental trials for all designs were generated. Random uniform responses were simulated for all models. R-square, Akaike and Bayesian Information Criterion for the fitted models were noted. One-way ANOVA and Tukey’s multiple comparison test were performed on these parameters. These models were evaluated based on the number of experimental trials generated in addition to the results of the statistical analyses. D-optimal design generated 12 trials in its model, which was lesser in comparison to both Central Composite and Box-Behnken designs. The R-square values of the fitted models were found to possess a statistically significant difference (P<0.0001). D-optimal design not only had the highest mean R-square value (0.7231), but also possessed the lowest means for both Akaike and Bayesian Information Criterion. The D-optimal design was recommended for generation of response surfaces, based on the assessment of the above parameters.
Experimental design of natural and accellerated bone and wood ageing
DEFF Research Database (Denmark)
Facorellis, Y.; Pournou, A.; Richter, Jane
2015-01-01
This paper presents the experimental design for natural and accelerated ageing of bone and wood samples found in museum conditions that was conceived as part of the INVENVORG (Thales Research Funding Program – NRSF) investigating the effects of the environmental factors on natural organic materials....
Evaluation of process parameters in the industrial scale production of fish nuggets
Directory of Open Access Journals (Sweden)
Adriane da Silva
2011-06-01
Full Text Available This work reports the use of experimental design for the assessment of the effects of process parameters on the production of fish nuggets in an industrial scale environment. The effect of independent factors on the physicochemical and microbiological parameters was investigated through a full 24 experimental design. The studied factors included the temperature of fish fillet and pulp in the mixer, the temperature of the added fat, the temperature of water and the ratio of protein extraction time to emulsion time. The physicochemical analyses showed that the higher temperature of the pulp and fillet of fish, the lower the protein in the final product. Microbiological analyses revealed that the counting of Staphylococcus coagulase positive, total and thermo-tolerant coliforms were in accordance with the current legislation.
Experimental study and process parameters analysis on the vacuum cooling of iceberg lettuce
International Nuclear Information System (INIS)
He Suyan; Li Yunfei
2008-01-01
The vacuum cooling of iceberg lettuce was described in this paper. Based on the energy and mass balance, a mathematical model was developed to analyze the performance of the vacuum cooler and the evaporation-boiling phenomena during vacuum cooling of iceberg lettuce. The temporal trends of total system pressure, produce temperature such as surface temperature, center temperature, mass-average temperature, the weight loss of iceberg lettuce during vacuum cooling were predicted. Validation experimentation is achieved in the designed vacuum cooler. The experimental data were compared with the simulation results. It was found that the differences of the temperature between the simulation and the experiments were within 1 deg. C. The amount of water evaporated from the iceberg lettuce by simulation was 3.32% during the whole vacuum cooling, while the tested water loss rate was 2.97%, the maximal deviation of weight loss was within 0.59%. The simulation results agreed well with the experimental data
Experimental study and process parameters analysis on the vacuum cooling of iceberg lettuce
Energy Technology Data Exchange (ETDEWEB)
He, Su-Yan [School of Mechanical and Electrical Engineering, Qingdao University, Qingdao 266071 (China); Li, Yun-Fei [Department of Food Science and Engineering, School of Agriculture and Biology, Shanghai Jiao Tong University (China)
2008-10-15
The vacuum cooling of iceberg lettuce was described in this paper. Based on the energy and mass balance, a mathematical model was developed to analyze the performance of the vacuum cooler and the evaporation-boiling phenomena during vacuum cooling of iceberg lettuce. The temporal trends of total system pressure, produce temperature such as surface temperature, center temperature, mass-average temperature, the weight loss of iceberg lettuce during vacuum cooling were predicted. Validation experimentation is achieved in the designed vacuum cooler. The experimental data were compared with the simulation results. It was found that the differences of the temperature between the simulation and the experiments were within 1{sup o}C. The amount of water evaporated from the iceberg lettuce by simulation was 3.32% during the whole vacuum cooling, while the tested water loss rate was 2.97%, the maximal deviation of weight loss was within 0.59%. The simulation results agreed well with the experimental data. (author)
Experimental study and process parameters analysis on the vacuum cooling of iceberg lettuce
Energy Technology Data Exchange (ETDEWEB)
He Suyan [School of Mechanical and Electrical Engineering, Qingdao University, Qingdao 266071 (China)], E-mail: hesuyan67829@sina.com; Li Yunfei [Department of Food Science and Engineering, School of Agriculture and Biology, Shanghai Jiao Tong University (China)
2008-10-15
The vacuum cooling of iceberg lettuce was described in this paper. Based on the energy and mass balance, a mathematical model was developed to analyze the performance of the vacuum cooler and the evaporation-boiling phenomena during vacuum cooling of iceberg lettuce. The temporal trends of total system pressure, produce temperature such as surface temperature, center temperature, mass-average temperature, the weight loss of iceberg lettuce during vacuum cooling were predicted. Validation experimentation is achieved in the designed vacuum cooler. The experimental data were compared with the simulation results. It was found that the differences of the temperature between the simulation and the experiments were within 1 deg. C. The amount of water evaporated from the iceberg lettuce by simulation was 3.32% during the whole vacuum cooling, while the tested water loss rate was 2.97%, the maximal deviation of weight loss was within 0.59%. The simulation results agreed well with the experimental data.
Design and Development of Data Acquisition System Process Parameters of Kartini Reactor
International Nuclear Information System (INIS)
Prajitno
2009-01-01
Design and development of computer program for data acquisition system of process parameters of the Kartini reactor have been done. System was designed using industrial computer which equipped with electronic module PCL-812PG. The function of computer is to take parameter data of reactor process, processing the data and displaying on the numeric form and bar graphic. Electronics module PCL- 12PG was installed in one of computer slot, functions to convert from analog signal to digital, received digital status signal and produce digital output. The analog signal and digital status got from logarithmic power channel, linear power channel dan three control rod. Result of data acquisition is merged in the form of ASCII characters block, send to the master computer serially with communications protocols RS-232. Computer program which has been developed was tested and used for monitoring Kartini reactor operation and give good performance result. (author)
Energy Technology Data Exchange (ETDEWEB)
Sung, Baek Ju; Kim, Do Sik [Korea Institute of Machinery and Materials, Daejeon (Korea, Republic of)
2014-05-15
The precision hydraulic valve is widely used in various industrial field like aircraft, automobile, and general machinery. Servo actuator is the most important device for driving the precise hydraulic valve. The reliable operation of servo actuator effects on the overall hydraulic system. The performance of servo actuator relies on frequency response and step response according to arbitrary input signal. In this paper, we performed the analysis for the components of servo actuator to satisfy the reliable operation and response characteristics through the reliability analysis, and also induced the design parameters to realize the reliable operation and fast response characteristics of servo actuator for hydraulic valve operation through the empirical knowledge of experts and electromagnetic theories. We suggested the design equations to determine the values of design parameters of servo actuator as like bobbin size, length of yoke and plunger and turn number of coil, and verified the achieved design values through FEM analysis and performance tests using some prototypes of servo actuators adapted in hydraulic valve.
Lee, Il-Sun; Byeon, Jung-Ho; Kim, Young-shin; Kwon, Yong-Ju
2014-01-01
The purpose of this study was to develop a model for measuring experimental design ability based on functional magnetic resonance imaging (fMRI) during biological inquiry. More specifically, the researchers developed an experimental design task that measures experimental design ability. Using the developed experimental design task, they measured…
Impact of major design parameters on the economics of Tokamak power plants
International Nuclear Information System (INIS)
Abdou, M.A.; Ehst, D.; Maroni, V.; Stacey, W.M. Jr.
1977-11-01
A parametric systems studies program is now in an active stage at Argonne National Laboratory. This paper presents a summary of results from this systems analysis effort. The impact of major design parameters on the economics of tokamak power plants is examined. The major parameters considered are: (1) the plant power rating; (2) toroidal-field strength; (3) plasma β/sub t/; (4) aspect ratio; (5) plasma elongation; (6) inner blanket/shield thickness; and (7) neutron wall load. The performance characteristics and economics of tokamak power plants are also compared for two structural materials
Directory of Open Access Journals (Sweden)
Chuanqiang Yu
2015-01-01
Full Text Available Deteriorating systems, which are subject to both continuous smooth degradation and additional abrupt damages due to a shock process, can be often encountered in engineering. Modeling the degradation evolution and predicting the lifetime of this kind of systems are both interesting and challenging in practice. In this paper, we model the degradation trajectory of the deteriorating system by a random coefficient regression (RCR model with positive jumps, where the RCR part is used to model the continuous smooth degradation of the system and the jump part is used to characterize the abrupt damages due to random shocks. Based on a specified threshold level, the probability density function (PDF and cumulative distribution function (CDF of the lifetime can be derived analytically. The unknown parameters associated with the derived lifetime distributions can be estimated via a well-designed parameter estimation procedure on the basis of the available degradation recordings of the deteriorating systems. An illustrative example is finally provided to demonstrate the implementation and superiority of the newly proposed lifetime prediction method. The experimental results reveal that our proposed lifetime prediction method with the dedicated parameter estimation strategy can get more accurate lifetime predictions than the rival model in literature.
Specification of PWR UO2 pellet design parameters with the fuel performance code FRAPCON-1
International Nuclear Information System (INIS)
Silva, A.T.; Marra Neto, A.
1988-08-01
UO 2 pellet design parameters are analysed to verify their influence in the fuel basic properties and in its performance under irradiation in pressurized water reactors. Three groups of parameters are discussed: 1) content of fissionable and impurity materials; 2) stoichiometry; 3) density pore morpholoy, and microstructure. A methodology is applied with the fuel performance program FRAPCON-1 to specify these parameters. (author [pt
Energy Technology Data Exchange (ETDEWEB)
Dotta, A.L.B.; Costa, C.A.; Farias, M.C.M. [Universidade de Caxias do Sul (UCS), RS (Brazil); Cunha, M.A da, E-mail: alinebandotta@gmail.com [Universidade Federal do Rio Grande do Sul (UFRGS), Caxias do Sul, RS (Brazil)
2016-07-01
This work represents the tribological study of Al{sub 2}O{sub 3} obtained by LPIM using the experimental design technique to evaluate the interaction of the tribological parameters with the friction and wear. The LPIM process was performed at 90 °C for 24 h. The average friction coefficient for the factorial experimental design varied significantly with the load and the speed when Al{sub 2}O{sub 3} was tested with the steel counter body. In general, the wear coefficient was lower for the tribological pair Al{sub 2}O{sub 3}-steel, in which occurred the formation of an iron oxide tribofilm on the surface. As for the Al{sub 2}O{sub 3}-Al{sub 2}O{sub 3} pair, an intergranular fracture of the surface occurred, in addition to the presence of material adhered on the tracks. (author)
Overview of International Thermonuclear Experimental Reactor (ITER) engineering design activities*
Shimomura, Y.
1994-05-01
The International Thermonuclear Experimental Reactor (ITER) [International Thermonuclear Experimental Reactor (ITER) (International Atomic Energy Agency, Vienna, 1988), ITER Documentation Series, No. 1] project is a multiphased project, presently proceeding under the auspices of the International Atomic Energy Agency according to the terms of a four-party agreement among the European Atomic Energy Community (EC), the Government of Japan (JA), the Government of the Russian Federation (RF), and the Government of the United States (US), ``the Parties.'' The ITER project is based on the tokamak, a Russian invention, and has since been brought to a high level of development in all major fusion programs in the world. The objective of ITER is to demonstrate the scientific and technological feasibility of fusion energy for peaceful purposes. The ITER design is being developed, with support from the Parties' four Home Teams and is in progress by the Joint Central Team. An overview of ITER Design activities is presented.
Methods for experimental design principles and applications for physicists and chemists
Goupy, J
1993-01-01
A method for organizing and conducting scientific experiments is described in this volume which enables experimenters to reduce the number of trials run, while retaining all the parameters that may influence the result. The choice of ideal experiments is based on mathematical concepts, but the author adopts a practical approach and uses theory only when necessary. Written for experimenters by an experimenter, it is an introduction to the philosophy of scientific investigation. Researchers with limited time and resources at their disposal will find this text a valuable guide for solving specific problems efficiently. The presentation makes extensive use of examples, and the approach and methods are graphical rather than numerical. All calculations can be performed on a personal computer; readers are assumed to have no previous knowledge of the subject. The presentation is such that the beginner may acquire a thorough understanding of the basic concepts. However, there is also sufficient material to challenge t...
International Nuclear Information System (INIS)
Carton, J.G.; Olabi, A.G.
2010-01-01
Low temperature hydrogen fuel cells are electrochemical devices which offer a promising alternative to traditional power sources. Fuel cells produce electricity with a reaction of the fuel (hydrogen) and air. Fuel cells have the advantage of being clean; only producing water and heat as by products. The efficiency of a fuel cell varies depending on the type; SOFC with CHP for example, can have a system efficiency of up to 65%. What the Authors present here is a comparison between three different configurations of flow plates of a proton exchange membrane fuel cell, the manufacturer's serpentine flow plate and two new configurations; the maze flow plate and the parallel flow plate. A study of the input parameters affecting output responses of voltage, current, power and efficiency of a fuel cell is performed through experimentation. The results were taken from direct readings of the fuel cell and from polarisation curves produced. This information was then analysed through a design of experiment to investigate the effects of the changing parameters on different configurations of the fuel cell's flow plates. The results indicate that, in relation to current and voltage response of the polarisation curve and the corresponding graphs produced from the DOE, the serpentine flow plate design is a much more effective design than the maze or parallel flow plate design. It was noted that the parallel flow plate performed reasonably well at higher pressures but over all statically the serpentine flow plate performed better.