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Sample records for exhibit spatial stability

  1. Chimpanzees and bonobos exhibit divergent spatial memory development.

    Science.gov (United States)

    Rosati, Alexandra G; Hare, Brian

    2012-11-01

    Spatial cognition and memory are critical cognitive skills underlying foraging behaviors for all primates. While the emergence of these skills has been the focus of much research on human children, little is known about ontogenetic patterns shaping spatial cognition in other species. Comparative developmental studies of nonhuman apes can illuminate which aspects of human spatial development are shared with other primates, versus which aspects are unique to our lineage. Here we present three studies examining spatial memory development in our closest living relatives, chimpanzees (Pan troglodytes) and bonobos (P. paniscus). We first compared memory in a naturalistic foraging task where apes had to recall the location of resources hidden in a large outdoor enclosure with a variety of landmarks (Studies 1 and 2). We then compared older apes using a matched memory choice paradigm (Study 3). We found that chimpanzees exhibited more accurate spatial memory than bonobos across contexts, supporting predictions from these species' different feeding ecologies. Furthermore, chimpanzees - but not bonobos - showed developmental improvements in spatial memory, indicating that bonobos exhibit cognitive paedomorphism (delays in developmental timing) in their spatial abilities relative to chimpanzees. Together, these results indicate that the development of spatial memory may differ even between closely related species. Moreover, changes in the spatial domain can emerge during nonhuman ape ontogeny, much like some changes seen in human children. © 2012 Blackwell Publishing Ltd.

  2. A simplified spatial model for BWR stability

    International Nuclear Information System (INIS)

    Berman, Y.; Lederer, Y.; Meron, E.

    2012-01-01

    A spatial reduced order model for the study of BWR stability, based on the phenomenological model of March-Leuba et al., is presented. As one dimensional spatial dependence of the neutron flux, fuel temperature and void fraction is introduced, it is possible to describe both global and regional oscillations of the reactor power. Both linear stability analysis and numerical analysis were applied in order to describe the parameters which govern the model stability. The results were found qualitatively similar to past results. Doppler reactivity feedback was found essential for the explanation of the different regions of the flow-power stability map. (authors)

  3. Stability of a spatial model of social interactions

    International Nuclear Information System (INIS)

    Bragard, Jean; Mossay, Pascal

    2016-01-01

    We study a spatial model of social interactions. Though the properties of the spatial equilibrium have been largely discussed in the existing literature, the stability of equilibrium remains an unaddressed issue. Our aim is to fill up this gap by introducing dynamics in the model and by determining the stability of equilibrium. First we derive a variational equation useful for the stability analysis. This allows to study the corresponding eigenvalue problem. While odd modes are shown to be always stable, there is a single even mode of which stability depends on the model parameters. Finally various numerical simulations illustrate our theoretical results.

  4. Stability of spatially developing boundary layers

    Science.gov (United States)

    Govindarajan, Rama

    1993-07-01

    A new formulation of the stability of boundary-layer flows in pressure gradients is presented, taking into account the spatial development of the flow. The formulation assumes that disturbance wavelength and eigenfunction vary downstream no more rapidly than the boundary-layer thickness, and includes all terms of O(1) and O(R(exp -1)) in the boundary-layer Reynolds number R. Although containing the Orr-Sommerfeld operator, the present approach does not yield the Orr-Sommerfeld equation in any rational limit. In Blasius flow, the present stability equation is consistent with that of Bertolotti et al. (1992) to terms of O(R(exp -1)). For the Falkner-Skan similarity solutions neutral boundaries are computed without the necessity of having to march in space. Results show that the effects of spatial growth are striking in flows subjected to adverse pressure gradients.

  5. Relationship between plant diversity and spatial stability of ...

    African Journals Online (AJOL)

    Theory predicts that greater biodiversity is expected to enhance stability of ecosystem. In field experiment, we created some diversity-level assemblages by removing functional groups across two grassland ecosystems and evaluated the responses of spatial stability of aboveground net primary productivity (ANPP) to varying ...

  6. Dispersal and metapopulation stability

    Directory of Open Access Journals (Sweden)

    Shaopeng Wang

    2015-10-01

    Full Text Available Metapopulation dynamics are jointly regulated by local and spatial factors. These factors may affect the dynamics of local populations and of the entire metapopulation differently. Previous studies have shown that dispersal can stabilize local populations; however, as dispersal also tends to increase spatial synchrony, its net effect on metapopulation stability has been controversial. Here we present a simple metapopulation model to study how dispersal, in interaction with other spatial and local processes, affects the temporal variability of metapopulations in a stochastic environment. Our results show that in homogeneous metapopulations, the local stabilizing and spatial synchronizing effects of dispersal cancel each other out, such that dispersal has no effect on metapopulation variability. This result is robust to moderate heterogeneities in local and spatial parameters. When local and spatial dynamics exhibit high heterogeneities, however, dispersal can either stabilize or destabilize metapopulation dynamics through various mechanisms. Our findings have important theoretical and practical implications. We show that dispersal functions as a form of spatial intraspecific mutualism in metapopulation dynamics and that its effect on metapopulation stability is opposite to that of interspecific competition on local community stability. Our results also suggest that conservation corridors should be designed with appreciation of spatial heterogeneities in population dynamics in order to maximize metapopulation stability.

  7. Spatial hole burning and spectral stability of a quantum-dot laser

    International Nuclear Information System (INIS)

    Savelyev, A. V.; Korenev, V. V.; Maximov, M. V.; Zhukov, A. E.

    2015-01-01

    The inhomogeneous intensity distribution of the optical model along the axis of a semiconductor quantum-dot laser results in spatial hole burning. The influence of this phenomenon on the stability of the multifrequency emission spectrum is studied when the optical transition of the quantum dots is characterized by considerable homogeneous broadening. The results of two models—in which inhomogeneous broadening is disregarded and taken into account—regarding the stability of the radiation spectrum under the influence of slight variation of the spectral loss dependence in the resonator are compared. Inhomogeneous distribution of the charge carriers (spatial hole burning) is found to be a critical factor in determining the form and stability of the spectrum

  8. Spatial hole burning and spectral stability of a quantum-dot laser

    Energy Technology Data Exchange (ETDEWEB)

    Savelyev, A. V., E-mail: savelev@mail.ioffe.ru; Korenev, V. V.; Maximov, M. V.; Zhukov, A. E. [Russian Academy of Sciences, Nanotechnology Center, St. Petersburg Academic University (Russian Federation)

    2015-11-15

    The inhomogeneous intensity distribution of the optical model along the axis of a semiconductor quantum-dot laser results in spatial hole burning. The influence of this phenomenon on the stability of the multifrequency emission spectrum is studied when the optical transition of the quantum dots is characterized by considerable homogeneous broadening. The results of two models—in which inhomogeneous broadening is disregarded and taken into account—regarding the stability of the radiation spectrum under the influence of slight variation of the spectral loss dependence in the resonator are compared. Inhomogeneous distribution of the charge carriers (spatial hole burning) is found to be a critical factor in determining the form and stability of the spectrum.

  9. Walk, Look, Remember: The Influence of the Gallery's Spatial Layout on Human Memory for an Art Exhibition.

    Science.gov (United States)

    Krukar, Jakub

    2014-09-01

    The spatial organisation of museums and its influence on the visitor experience has been the subject of numerous studies. Previous research, despite reporting some actual behavioural correlates, rarely had the possibility to investigate the cognitive processes of the art viewers. In the museum context, where spatial layout is one of the most powerful curatorial tools available, attention and memory can be measured as a means of establishing whether or not the gallery fulfils its function as a space for contemplating art. In this exploratory experiment, 32 participants split into two groups explored an experimental, non-public exhibition and completed two unanticipated memory tests afterwards. The results show that some spatial characteristics of an exhibition can inhibit the recall of pictures and shift the focus to perceptual salience of the artworks.

  10. Children with Chromosome 22q11.2 Deletion Syndrome Exhibit Impaired Spatial Working Memory

    Science.gov (United States)

    Wong, Ling M.; Riggins, Tracy; Harvey, Danielle; Cabaral, Margarita; Simon, Tony J.

    2014-01-01

    Individuals with chromosome 22q11.2 deletion syndrome (22q11.2DS) have been shown to have impairments in processing spatiotemporal information. The authors examined whether children with 22q11.2DS exhibit impairments in spatial working memory performance due to these weaknesses, even when controlling for maintenance of attention. Children with…

  11. Optimal exploitation of spatially distributed trophic resources and population stability

    Science.gov (United States)

    Basset, A.; Fedele, M.; DeAngelis, D.L.

    2002-01-01

    The relationships between optimal foraging of individuals and population stability are addressed by testing, with a spatially explicit model, the effect of patch departure behaviour on individual energetics and population stability. A factorial experimental design was used to analyse the relevance of the behavioural factor in relation to three factors that are known to affect individual energetics; i.e. resource growth rate (RGR), assimilation efficiency (AE), and body size of individuals. The factorial combination of these factors produced 432 cases, and 1000 replicate simulations were run for each case. Net energy intake rates of the modelled consumers increased with increasing RGR, consumer AE, and consumer body size, as expected. Moreover, through their patch departure behaviour, by selecting the resource level at which they departed from the patch, individuals managed to substantially increase their net energy intake rates. Population stability was also affected by the behavioural factors and by the other factors, but with highly non-linear responses. Whenever resources were limiting for the consumers because of low RGR, large individual body size or low AE, population density at the equilibrium was directly related to the patch departure behaviour; on the other hand, optimal patch departure behaviour, which maximised the net energy intake at the individual level, had a negative influence on population stability whenever resource availability was high for the consumers. The consumer growth rate (r) and numerical dynamics, as well as the spatial and temporal fluctuations of resource density, which were the proximate causes of population stability or instability, were affected by the behavioural factor as strongly or even more strongly than by the others factors considered here. Therefore, patch departure behaviour can act as a feedback control of individual energetics, allowing consumers to optimise a potential trade-off between short-term individual fitness

  12. Walk, Look, Remember: The Influence of the Gallery’s Spatial Layout on Human Memory for an Art Exhibition

    Directory of Open Access Journals (Sweden)

    Jakub Krukar

    2014-07-01

    Full Text Available The spatial organisation of museums and its influence on the visitor experience has been the subject of numerous studies. Previous research, despite reporting some actual behavioural correlates, rarely had the possibility to investigate the cognitive processes of the art viewers. In the museum context, where spatial layout is one of the most powerful curatorial tools available, attention and memory can be measured as a means of establishing whether or not the gallery fulfils its function as a space for contemplating art. In this exploratory experiment, 32 participants split into two groups explored an experimental, non-public exhibition and completed two unanticipated memory tests afterwards. The results show that some spatial characteristics of an exhibition can inhibit the recall of pictures and shift the focus to perceptual salience of the artworks.

  13. Potential and flux field landscape theory. I. Global stability and dynamics of spatially dependent non-equilibrium systems.

    Science.gov (United States)

    Wu, Wei; Wang, Jin

    2013-09-28

    We established a potential and flux field landscape theory to quantify the global stability and dynamics of general spatially dependent non-equilibrium deterministic and stochastic systems. We extended our potential and flux landscape theory for spatially independent non-equilibrium stochastic systems described by Fokker-Planck equations to spatially dependent stochastic systems governed by general functional Fokker-Planck equations as well as functional Kramers-Moyal equations derived from master equations. Our general theory is applied to reaction-diffusion systems. For equilibrium spatially dependent systems with detailed balance, the potential field landscape alone, defined in terms of the steady state probability distribution functional, determines the global stability and dynamics of the system. The global stability of the system is closely related to the topography of the potential field landscape in terms of the basins of attraction and barrier heights in the field configuration state space. The effective driving force of the system is generated by the functional gradient of the potential field alone. For non-equilibrium spatially dependent systems, the curl probability flux field is indispensable in breaking detailed balance and creating non-equilibrium condition for the system. A complete characterization of the non-equilibrium dynamics of the spatially dependent system requires both the potential field and the curl probability flux field. While the non-equilibrium potential field landscape attracts the system down along the functional gradient similar to an electron moving in an electric field, the non-equilibrium flux field drives the system in a curly way similar to an electron moving in a magnetic field. In the small fluctuation limit, the intrinsic potential field as the small fluctuation limit of the potential field for spatially dependent non-equilibrium systems, which is closely related to the steady state probability distribution functional, is

  14. Strategy Diversity Stabilizes Mutualism through Investment Cycles, Phase Polymorphism, and Spatial Bubbles

    Science.gov (United States)

    Boza, Gergely; Kun, Ádám; Scheuring, István; Dieckmann, Ulf

    2012-01-01

    There is continuing interest in understanding factors that facilitate the evolution and stability of cooperation within and between species. Such interactions will often involve plasticity in investment behavior, in response to the interacting partner's investments. Our aim here is to investigate the evolution and stability of reciprocal investment behavior in interspecific interactions, a key phenomenon strongly supported by experimental observations. In particular, we present a comprehensive analysis of a continuous reciprocal investment game between mutualists, both in well-mixed and spatially structured populations, and we demonstrate a series of novel mechanisms for maintaining interspecific mutualism. We demonstrate that mutualistic partners invariably follow investment cycles, during which mutualism first increases, before both partners eventually reduce their investments to zero, so that these cycles always conclude with full defection. We show that the key mechanism for stabilizing mutualism is phase polymorphism along the investment cycle. Although mutualistic partners perpetually change their strategies, the community-level distribution of investment levels becomes stationary. In spatially structured populations, the maintenance of polymorphism is further facilitated by dynamic mosaic structures, in which mutualistic partners form expanding and collapsing spatial bubbles or clusters. Additionally, we reveal strategy-diversity thresholds, both for well-mixed and spatially structured mutualistic communities, and discuss factors for meeting these thresholds, and thus maintaining mutualism. Our results demonstrate that interspecific mutualism, when considered as plastic investment behavior, can be unstable, and, in agreement with empirical observations, may involve a polymorphism of investment levels, varying both in space and in time. Identifying the mechanisms maintaining such polymorphism, and hence mutualism in natural communities, provides a significant

  15. Non Lyapunov stability of a constant spatially developing 2-D gas flow

    Science.gov (United States)

    Balint, Agneta M.; Balint, Stefan; Tanasie, Loredana

    2017-01-01

    Different types of stabilities (global, local) and instabilities (global absolute, local convective) of the constant spatially developing 2-D gas flow are analyzed in a particular phase space of continuously differentiable functions, endowed with the usual algebraic operations and the topology generated by the uniform convergence on the plane. For this purpose the Euler equations linearized at the constant flow are used. The Lyapunov stability analysis was presented in [1] and this paper is a continuation of [1].

  16. Reliability and Minimum Detectable Change of Temporal-Spatial, Kinematic, and Dynamic Stability Measures during Perturbed Gait.

    Directory of Open Access Journals (Sweden)

    Christopher A Rábago

    Full Text Available Temporal-spatial, kinematic variability, and dynamic stability measures collected during perturbation-based assessment paradigms are often used to identify dysfunction associated with gait instability. However, it remains unclear which measures are most reliable for detecting and tracking responses to perturbations. This study systematically determined the between-session reliability and minimum detectable change values of temporal-spatial, kinematic variability, and dynamic stability measures during three types of perturbed gait. Twenty young healthy adults completed two identical testing sessions two weeks apart, comprised of an unperturbed and three perturbed (cognitive, physical, and visual walking conditions in a virtual reality environment. Within each session, perturbation responses were compared to unperturbed walking using paired t-tests. Between-session reliability and minimum detectable change values were also calculated for each measure and condition. All temporal-spatial, kinematic variability and dynamic stability measures demonstrated fair to excellent between-session reliability. Minimal detectable change values, normalized to mean values ranged from 1-50%. Step width mean and variability measures demonstrated the greatest response to perturbations with excellent between-session reliability and low minimum detectable change values. Orbital stability measures demonstrated specificity to perturbation direction and sensitivity with excellent between-session reliability and low minimum detectable change values. We observed substantially greater between-session reliability and lower minimum detectable change values for local stability measures than previously described which may be the result of averaging across trials within a session and using velocity versus acceleration data for reconstruction of state spaces. Across all perturbation types, temporal-spatial, orbital and local measures were the most reliable measures with the

  17. One-way spatial integration of Navier-Stokes equations: stability of wall-bounded flows

    Science.gov (United States)

    Rigas, Georgios; Colonius, Tim; Towne, Aaron; Beyar, Michael

    2016-11-01

    For three-dimensional flows, questions of stability, receptivity, secondary flows, and coherent structures require the solution of large partial-derivative eigenvalue problems. Reduced-order approximations are thus required for engineering prediction since these problems are often computationally intractable or prohibitively expensive. For spatially slowly evolving flows, such as jets and boundary layers, a regularization of the equations of motion sometimes permits a fast spatial marching procedure that results in a huge reduction in computational cost. Recently, a novel one-way spatial marching algorithm has been developed by Towne & Colonius. The new method overcomes the principle flaw observed in Parabolized Stability Equations (PSE), namely the ad hoc regularization that removes upstream propagating modes. The one-way method correctly parabolizes the flow equations based on estimating, in a computationally efficient way, the local spectrum in each cross-stream plane and an efficient spectral filter eliminates modes with upstream group velocity. Results from the application of the method to wall-bounded flows will be presented and compared with predictions from the full linearized compressible Navier-Stokes equations and PSE.

  18. Biological soil crusts exhibit a dynamic response to seasonal rain and release from grazing with implications for soil stability

    Science.gov (United States)

    Jimenez, Aguilar A.; Huber-Sannwald, E.; Belnap, J.; Smart, D.R.; Arredondo, Moreno J.T.

    2009-01-01

    In Northern Mexico, long-term grazing has substantially degraded semiarid landscapes. In semiarid systems, ecological and hydrological processes are strongly coupled by patchy plant distribution and biological soil crust (BSC) cover in plant-free interspaces. In this study, we asked: 1) how responsive are BSC cover/composition to a drying/wetting cycle and two-year grazing removal, and 2) what are the implications for soil erosion? We characterized BSC morphotypes and their influence on soil stability under grazed/non-grazed conditions during a dry and wet season. Light- and dark-colored cyanobacteria were dominant at the plant tussock and community level. Cover changes in these two groups differed after a rainy season and in response to grazing removal. Lichens with continuous thalli were more vulnerable to grazing than those with semi-continuous/discontinuous thalli after the dry season. Microsites around tussocks facilitated BSC colonization compared to interspaces. Lichen and cyanobacteria morphotypes differentially enhanced resistance to soil erosion; consequently, surface soil stability depends on the spatial distribution of BSC morphotypes, suggesting soil stability may be as dynamic as changes in the type of BSC cover. Longer-term spatially detailed studies are necessary to elicit spatiotemporal dynamics of BSC communities and their functional role in biotically and abiotically variable environments. ?? 2009 Elsevier Ltd.

  19. Campylobacter jejuni sequence types show remarkable spatial and temporal stability in Blackbirds

    Directory of Open Access Journals (Sweden)

    Petra Griekspoor

    2015-12-01

    Full Text Available Background: The zoonotic bacterium Campylobacter jejuni has a broad host range but is especially associated with birds, both domestic and wild. Earlier studies have indicated thrushes of the genus Turdus in Europe to be frequently colonized with C. jejuni, and predominately with host-associated specific genotypes. The European Blackbird Turdus merula has a large distribution in Europe, including some oceanic islands, and was also introduced to Australia by European immigrants in the 1850s. Methods: The host specificity and temporal stability of European Blackbird C. jejuni was investigated with multilocus sequence typing in a set of isolates collected from Sweden, Australia, and The Azores. Results: Remarkably, we found that the Swedish, Australian, and Azorean isolates were genetically highly similar, despite extensive spatial and temporal isolation. This indicates adaptation, exquisite specificity, and stability in time for European Blackbirds, which is in sharp contrast with the high levels of recombination and mutation found in poultry-related C. jejuni genotypes. Conclusion: The maintenance of host-specific signals in spatially and temporally separated C. jejuni populations suggests the existence of strong purifying selection for this bacterium in European Blackbirds.

  20. Existence and Stability of Spatial Plane Waves for the Incompressible Navier-Stokes in R^3

    Science.gov (United States)

    Correia, Simão; Figueira, Mário

    2018-03-01

    We consider the three-dimensional incompressible Navier-Stokes equation on the whole space. We observe that this system admits a L^∞ family of global spatial plane wave solutions, which are connected with the two-dimensional equation. We then proceed to prove local well-posedness over a space which includes L^3(R^3) and these solutions. Finally, we prove L^3-stability of spatial plane waves, with no condition on their size.

  1. A bistriphenylamine-substituted spirobifluorene derivative exhibiting excellent nonlinearity/transparency/thermal stability trade-off and strong two-photon induced blue fluorescence

    International Nuclear Information System (INIS)

    Yin, Hongyao; Xiao, Haibo; Ding, Lei; Zhang, Chun; Ren, Aiming; Li, Bo

    2015-01-01

    A spirobifluorene-bridged donor/donor chromophore, 2,7-bis-(4-(N,N-diphenylamino)phen-1-yl)-9,9′-spirobifluorene (SPF-TP), was found to combine excellent transparency in the near UV–visible region (λ cut-off  ≤ 420 nm), large two-photon absorption cross-section (4.5 × 10 3 GM) and high thermal stability (T d  = 501 °C). In comparison to the reported two-photon absorption molecules, SPF-TP represents the best thermal stability so far described in the literature. The main electronic factors explaining the high two-photon absorption activities of SPF-TP were analyzed by theoretical calculations. Cyclic voltammograms were employed to explore the causes of the excellent transparency of SPF-TP. It was found that the spiroconjugation effect is responsible for the excellent nonlinearity/transparency/thermal stability trade-off in SPF-TP. In addition, SPF-TP is also a good two-photon induced blue fluorescent material with high fluorescence quantum yield (Φ = 0.90, in THF). - Highlights: • We report a molecule exhibiting excellent transparency. • The two-photon absorption cross-section is as large as 4.5 × 10 3 GM. • The molecule exhibits excellent thermal stability. • The molecule is a good two-photon induced blue fluorescent material. • The spiroconjugation effect explains the excellent properties

  2. A bistriphenylamine-substituted spirobifluorene derivative exhibiting excellent nonlinearity/transparency/thermal stability trade-off and strong two-photon induced blue fluorescence

    Energy Technology Data Exchange (ETDEWEB)

    Yin, Hongyao [Department of Chemistry, Shanghai Normal University, Shanghai 200234 (China); Xiao, Haibo, E-mail: xiaohb@shnu.edu.cn [Department of Chemistry, Shanghai Normal University, Shanghai 200234 (China); Ding, Lei [Department of Chemistry, Shanghai Normal University, Shanghai 200234 (China); Zhang, Chun; Ren, Aiming [State Key Laboratory of Theoretical and Computational Chemistry, Institute of Theoretical Chemistry, Jilin University, Changchun 130023 (China); Li, Bo [Key Laboratory of Polar Materials and Devices, Ministry of Education, East China Normal University, Shanghai 200241 (China)

    2015-02-01

    A spirobifluorene-bridged donor/donor chromophore, 2,7-bis-(4-(N,N-diphenylamino)phen-1-yl)-9,9′-spirobifluorene (SPF-TP), was found to combine excellent transparency in the near UV–visible region (λ{sub cut-off} ≤ 420 nm), large two-photon absorption cross-section (4.5 × 10{sup 3}GM) and high thermal stability (T{sub d} = 501 °C). In comparison to the reported two-photon absorption molecules, SPF-TP represents the best thermal stability so far described in the literature. The main electronic factors explaining the high two-photon absorption activities of SPF-TP were analyzed by theoretical calculations. Cyclic voltammograms were employed to explore the causes of the excellent transparency of SPF-TP. It was found that the spiroconjugation effect is responsible for the excellent nonlinearity/transparency/thermal stability trade-off in SPF-TP. In addition, SPF-TP is also a good two-photon induced blue fluorescent material with high fluorescence quantum yield (Φ = 0.90, in THF). - Highlights: • We report a molecule exhibiting excellent transparency. • The two-photon absorption cross-section is as large as 4.5 × 10{sup 3}GM. • The molecule exhibits excellent thermal stability. • The molecule is a good two-photon induced blue fluorescent material. • The spiroconjugation effect explains the excellent properties.

  3. Optical wall dynamics induced by coexistence of monostable and bistable spatial regions.

    Science.gov (United States)

    Odent, V; Louvergneaux, E; Clerc, M G; Andrade-Silva, I

    2016-11-01

    When nonequilibrium extended homogeneous systems exhibit multistability, it leads to the presence of domain walls between the existing equilibria. Depending on the stability of the steady states, the dynamics differs. Here, we consider the interface dynamics in the case of a spatially inhomogeneous system, namely, an optical system where the control parameter is spatially Gaussian. Then interfaces connect the monostable and the bistable nonuniform states that are associated with two distinct spatial regions. The coexistence of these two regions of different stability induces relaxation dynamics and the propagation of a wall with a time-dependent speed. We emphasize analytically these two dynamical behaviors using a generic bistable model. Experimentally, an inhomogeneous Gaussian light beam traveling through either a dye-doped liquid crystal cell or a Kerr cavity depicts these behaviors, in agreement with the theoretical predictions.

  4. Spatial and temporal stability of temperature in the first-level basins of China during 1951-2013

    Science.gov (United States)

    Cheng, Yuting; Li, Peng; Xu, Guoce; Li, Zhanbin; Cheng, Shengdong; Wang, Bin; Zhao, Binhua

    2018-05-01

    In recent years, global warming has attracted great attention around the world. Temperature change is not only involved in global climate change but also closely linked to economic development, the ecological environment, and agricultural production. In this study, based on temperature data recorded by 756 meteorological stations in China during 1951-2013, the spatial and temporal stability characteristics of annual temperature in China and its first-level basins were investigated using the rank correlation coefficient method, the relative difference method, rescaled range (R/S) analysis, and wavelet transforms. The results showed that during 1951-2013, the spatial variation of annual temperature belonged to moderate variability in the national level. Among the first-level basins, the largest variation coefficient was 114% in the Songhuajiang basin and the smallest variation coefficient was 10% in the Huaihe basin. During 1951-2013, the spatial distribution pattern of annual temperature presented extremely strong spatial and temporal stability characteristics in the national level. The variation range of Spearman's rank correlation coefficient was 0.97-0.99, and the spatial distribution pattern of annual temperature showed an increasing trend. In the national level, the Liaohe basin, the rivers in the southwestern region, the Haihe basin, the Yellow River basin, the Yangtze River basin, the Huaihe basin, the rivers in the southeastern region, and the Pearl River basin all had representative meteorological stations for annual temperature. In the Songhuajiang basin and the rivers in the northwestern region, there was no representative meteorological station. R/S analysis, the Mann-Kendall test, and the Morlet wavelet analysis of annual temperature showed that the best representative meteorological station could reflect the variation trend and the main periodic changes of annual temperature in the region. Therefore, strong temporal stability characteristics exist for

  5. Exact bright and dark spatial soliton solutions in saturable nonlinear media

    International Nuclear Information System (INIS)

    Calvo, Gabriel F.; Belmonte-Beitia, Juan; Perez-Garcia, Victor M.

    2009-01-01

    We present exact analytical bright and dark (black and grey) solitary wave solutions of a nonlinear Schroedinger-type equation describing the propagation of spatial beams in media exhibiting a saturable nonlinearity (such as centrosymmetric photorefractive materials). A qualitative study of the stationary equation is carried out together with a discussion of the stability of the solutions.

  6. 18 CFR 50.7 - Applications: exhibits.

    Science.gov (United States)

    2010-04-01

    ... systems, including the special protective systems' automatic switching or load shedding system; and (ii... transfer capability (NITC); system protection; and system stability. (3) A stability analysis including... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Applications: exhibits...

  7. a Simple Spatially Weighted Measure of Temporal Stability for Data with Limited Temporal Observations

    Science.gov (United States)

    Piburn, J.; Stewart, R.; Morton, A.

    2017-10-01

    Identifying erratic or unstable time-series is an area of interest to many fields. Recently, there have been successful developments towards this goal. These new developed methodologies however come from domains where it is typical to have several thousand or more temporal observations. This creates a challenge when attempting to apply these methodologies to time-series with much fewer temporal observations such as for socio-cultural understanding, a domain where a typical time series of interest might only consist of 20-30 annual observations. Most existing methodologies simply cannot say anything interesting with so few data points, yet researchers are still tasked to work within in the confines of the data. Recently a method for characterizing instability in a time series with limitedtemporal observations was published. This method, Attribute Stability Index (ASI), uses an approximate entropy based method tocharacterize a time series' instability. In this paper we propose an explicitly spatially weighted extension of the Attribute StabilityIndex. By including a mechanism to account for spatial autocorrelation, this work represents a novel approach for the characterizationof space-time instability. As a case study we explore national youth male unemployment across the world from 1991-2014.

  8. Spatial scale of similarity as an indicator of metacommunity stability in exploited marine systems.

    Science.gov (United States)

    Shackell, Nancy L; Fisher, Jonathan A D; Frank, Kenneth T; Lawton, Peter

    2012-01-01

    The spatial scale of similarity among fish communities is characteristically large in temperate marine systems: connectivity is enhanced by high rates of dispersal during the larval/juvenile stages and the increased mobility of large-bodied fish. A larger spatial scale of similarity (low beta diversity) is advantageous in heavily exploited systems because locally depleted populations are more likely to be "rescued" by neighboring areas. We explored whether the spatial scale of similarity changed from 1970 to 2006 due to overfishing of dominant, large-bodied groundfish across a 300 000-km2 region of the Northwest Atlantic. Annually, similarities among communities decayed slowly with increasing geographic distance in this open system, but through time the decorrelation distance declined by 33%, concomitant with widespread reductions in biomass, body size, and community evenness. The decline in connectivity stemmed from an erosion of community similarity among local subregions separated by distances as small as 100 km. Larger fish, of the same species, contribute proportionally more viable offspring, so observed body size reductions will have affected maternal output. The cumulative effect of nonlinear maternal influences on egg/larval quality may have compromised the spatial scale of effective larval dispersal, which may account for the delayed recovery of certain member species. Our study adds strong support for using the spatial scale of similarity as an indicator of metacommunity stability both to understand the spatial impacts of exploitation and to refine how spatial structure is used in management plans.

  9. High Quality Virtual Reality for Architectural Exhibitions

    DEFF Research Database (Denmark)

    Kreutzberg, Anette

    2016-01-01

    This paper will summarise the findings from creating and implementing a visually high quality Virtual Reality (VR) experiment as part of an international architecture exhibition. It was the aim to represent the architectural spatial qualities as well as the atmosphere created from combining natural...... and artificial lighting in a prominent not yet built project. The outcome is twofold: Findings concerning the integration of VR in an exhibition space and findings concerning the experience of the virtual space itself. In the exhibition, an important aspect was the unmanned exhibition space, requiring the VR...... experience to be self-explanatory. Observations of different visitor reactions to the unmanned VR experience compared with visitor reactions at guided tours with personal instructions are evaluated. Data on perception of realism, spatial quality and light in the VR model were collected with qualitative...

  10. Spatial stability of jets - the nonaxisymmetric fundamental and reflection modes

    International Nuclear Information System (INIS)

    Hardee, P.E.

    1987-01-01

    A spatial stability analysis of the relativistic dispersion relation governing the growth and propagation of harmonic components comprising a perturbation to the surface of a cylindrical jet is performed. The spatial growth of harmonic components associated with the nonaxisymmetric fundamental solution and reflection solutions of several Fourier modes are analyzed. Approximate analytical expressions describing resonant frequencies and wavelengths, and maximum growth rates at resonance applicable to relativistic jets are found from the dispersion relation, and the nature of the resonances is explored. On transonic jets there is only a fundamental solution for each Fourier mode with no resonance or maximum growth rate. On supersonic jets there is a fundamental solution and reflection solutions for each Fourier mode, and each solution contains a resonance at which the growth rate is a maximum. A numerical analysis of the fundamental and first three reflection solutions of the axisymmetric and first three nonaxisymmetric Fourier modes is performed. The numerical analysis is restricted to nonrelativistic flows but otherwise covers a broad range of Mach numbers and jet densities. The numerical results are used along with the analytical results to obtain accurate expressions for resonant frequencies, wavelengths, and growth rates as a function of Mach numnber and jet density. In all cases the fastest spatial growth rate at a given frequency is of harmonic components associated with the fundamental solution of one of the nonaxisymmetric Fourier modes. The application of these results to jet structure and implication of these results for jet structure in extragalactic radio sources are considered. 23 references

  11. Encouraging Spatial Talk: Using Children's Museums to Bolster Spatial Reasoning

    Science.gov (United States)

    Polinsky, Naomi; Perez, Jasmin; Grehl, Mora; McCrink, Koleen

    2017-01-01

    Longitudinal spatial language intervention studies have shown that greater exposure to spatial language improves children's performance on spatial tasks. Can short naturalistic, spatial language interactions also evoke improved spatial performance? In this study, parents were asked to interact with their child at a block wall exhibit in a…

  12. On the physical problem of spatial dimensions: an alternative procedure to stability arguments

    International Nuclear Information System (INIS)

    Caruso, F.; Xavier, R.M.

    1986-01-01

    The three-dimensionality of space as a physical problem is discussed. Consideration on previous works is done, in which it is showed that the n-dimensional solar system can be stable only for n=3 and, from quantum mechanics, that this is the case also for hydrogen atons. Thus the epistemological consequences of the use of the stability postulate to derive spatial dimensionality is critically reviewed. The distinguished role of Maxwell's eletromagnetic theory in the determination of space dimensionality is stressed. 'Metric versus' 'topological' 'arguments are compared and shown to apply respectively to 'matter' and 'fields'. (G.D.F.) [pt

  13. Effects of spatial variation in cohesion over the concrete-rock interface on dam sliding stability

    Directory of Open Access Journals (Sweden)

    Alexandra Krounis

    2015-12-01

    Full Text Available The limit equilibrium method (LEM is widely used for sliding stability evaluation of concrete gravity dams. Failure is then commonly assumed to occur along the entire sliding surface simultaneously. However, the brittle behaviour of bonded concrete-rock contacts, in combination with the varying stress over the interface, implies that the failure of bonded dam-foundation interfaces occurs progressively. In addition, the spatial variation in cohesion may introduce weak spots where failure can be initiated. Nonetheless, the combined effect of brittle failure and spatial variation in cohesion on the overall shear strength of the interface has not been studied previously. In this paper, numerical analyses are used to investigate the effect of brittle failure in combination with spatial variation in cohesion that is taken into account by random fields with different correlation lengths. The study concludes that a possible existence of weak spots along the interface has to be considered since it significantly reduces the overall shear strength of the interface, and implications for doing so are discussed.

  14. Spatial Domain Adaptive Control of Nonlinear Rotary Systems Subject to Spatially Periodic Disturbances

    Directory of Open Access Journals (Sweden)

    Yen-Hsiu Yang

    2012-01-01

    Full Text Available We propose a generic spatial domain control scheme for a class of nonlinear rotary systems of variable speeds and subject to spatially periodic disturbances. The nonlinear model of the rotary system in time domain is transformed into one in spatial domain employing a coordinate transformation with respect to angular displacement. Under the circumstances that measurement of the system states is not available, a nonlinear state observer is established for providing the estimated states. A two-degree-of-freedom spatial domain control configuration is then proposed to stabilize the system and improve the tracking performance. The first control module applies adaptive backstepping with projected parametric update and concentrates on robust stabilization of the closed-loop system. The second control module introduces an internal model of the periodic disturbances cascaded with a loop-shaping filter, which not only further reduces the tracking error but also improves parametric adaptation. The overall spatial domain output feedback adaptive control system is robust to model uncertainties and state estimated error and capable of rejecting spatially periodic disturbances under varying system speeds. Stability proof of the overall system is given. A design example with simulation demonstrates the applicability of the proposed design.

  15. Dynamics, stability, and statistics on lattices and networks

    International Nuclear Information System (INIS)

    Livi, Roberto

    2014-01-01

    These lectures aim at surveying some dynamical models that have been widely explored in the recent scientific literature as case studies of complex dynamical evolution, emerging from the spatio-temporal organization of several coupled dynamical variables. The first message is that a suitable mathematical description of such models needs tools and concepts borrowed from the general theory of dynamical systems and from out-of-equilibrium statistical mechanics. The second message is that the overall scenario is definitely reacher than the standard problems in these fields. For instance, systems exhibiting complex unpredictable evolution do not necessarily exhibit deterministic chaotic behavior (i.e., Lyapunov chaos) as it happens for dynamical models made of a few degrees of freedom. In fact, a very large number of spatially organized dynamical variables may yield unpredictable evolution even in the absence of Lyapunov instability. Such a mechanism may emerge from the combination of spatial extension and nonlinearity. Moreover, spatial extension allows one to introduce naturally disorder, or heterogeneity of the interactions as important ingredients for complex evolution. It is worth to point out that the models discussed in these lectures share such features, despite they have been inspired by quite different physical and biological problems. Along these lectures we describe also some of the technical tools employed for the study of such models, e.g., Lyapunov stability analysis, unpredictability indicators for “stable chaos,” hydrodynamic description of transport in low spatial dimension, spectral decomposition of stochastic dynamics on directed networks, etc

  16. On the spatial stability of a liquid jet in the presence of vapor cavities

    Energy Technology Data Exchange (ETDEWEB)

    Lü, Ming; Ning, Zhi, E-mail: zhining@bjtu.edu.cn; Lu, Mei; Yan, Kai; Fu, Juan; Sun, Chunhua [College of Mechanical and Electrical Engineering, Beijing Jiaotong University, Beijing 100044 (China)

    2013-11-15

    A dispersion equation describing the effect of temperature differences on the stability of three-dimensional cylindrical liquid jets in the presence of vapor cavities is presented by the use of linear stability analysis. The mathematical model and its solving method are verified by comparing them with the data in the literature, and then the effect of temperature differences between jet and surrounding gas on the spatial stability of liquid jet is investigated. Some conclusions can be drawn from the results of this investigation: (1) the temperature difference destabilizes the liquid jet when the jet liquid is cooler than the surrounding gas, (2) the smallest atomized droplet without taking into account the effect of temperature differences is significantly larger than that when the effect of temperature differences is taken into account, (3) the effect of temperature differences on the stability of liquid jet has little relationship with azimuthal wave modes, (4) cavitation destabilizes the liquid jet when the value of the bubble volume fraction is not greater than 0.1 (0 ≤ α ≤ 0.1), and the temperature difference can weaken this effect of cavitation on the stability of liquid jet, and (5) cavitation is responsible for generating smaller droplets, the effect of cavitation on the critical wave number with and without taking into account the effect of temperature differences is quite different, and temperature difference is likely to fully restrain the effect of cavitation on the critical wave number; however, cavitation is again responsible for generating smaller droplets despite the effect of temperature differences when the bubble volume fraction α = 0.1. These findings may explain some observations of practical atomizer performance.

  17. Within-field spatial distribution of Megacopta cribraria (Hemiptera: Plataspidae) in soybean (Fabales: Fabaceae).

    Science.gov (United States)

    Seiter, Nicholas J; Reay-Jones, Francis P F; Greene, Jeremy K

    2013-12-01

    The recently introduced plataspid Megacopta cribraria (F.) can infest fields of soybean (Glycine max (L.) Merrill) in the southeastern United States. Grid sampling in four soybean fields was conducted in 2011 and 2012 to study the spatial distribution of M. cribraria adults, nymphs, and egg masses. Peak oviposition typically occurred in early August, while peak levels of adults occurred in mid-late September. The overall sex ratio was slightly biased at 53.1 ± 0.2% (SEM) male. Sweep samples of nymphs were biased toward late instars. All three life stages exhibited a generally aggregated spatial distribution based on Taylor's power law, Iwao's patchiness regression, and spatial analysis by distance indices (SADIE). Interpolation maps of local SADIE aggregation indices showed clusters of adults and nymphs located at field edges, and mean densities of adults were higher in samples taken from field edges than in those taken from field interiors. Adults and nymphs were often spatially associated based on SADIE, indicating spatial stability across life stages.

  18. Dissipative Vortex Solitons in Defocusing Media with Spatially Inhomogeneous Nonlinear Absorption

    Science.gov (United States)

    Lai, Xian-Jing; Cai, Xiao-Ou; Zhang, Jie-Fang

    2018-02-01

    In this paper, by solving a complex nonlinear Schrödinger equation, radially symmetric dissipative vortex solitons are obtained analytically and are tested numerically. We find that spatially inhomogeneous nonlinear absorption gives rise to the stability of dissipative vortex solitons in self-defocusing nonlinear medium in the presence of constant linear gain. Numerical simulation reveals the interaction effect among linear gain and nonlinear loss in the azimuthal modulation instabilities of these vortices suppression. Apart from the uniform linear gain indeed affects the stability of vortex in this media, another noticeable feature of current setup is that the steep spatial modulation of the nonlinear absorption can suppress sidelobes effectively and support stable vortex solitons in situations with uniform linear gain. Under appropriate conditions, the vortex solitons can propagate stably and feature no symmetry breaking, although the beams exhibit radical compression and amplification as they propagate. Supported by the National Natural Science Foundation of China under Grant No. 11705164 and the Zhejiang Provincial Natural Science Foundation of China under Grant No. LQ16A040003

  19. Mapping fields of 137Cs contamination in soils in the context of their stability and hierarchical spatial structure

    Science.gov (United States)

    Korobova, E.; Romanov, S.

    2009-04-01

    could be used to investigate patterns of 137Cs spatial redistribution in the top soil layers. The portion of 137Cs conserved in top layers corresponded to the meso- and micro relief elements. The character and stability of 137Cs spatial structure was studied by measuring its activity within nested plots with different steps of 5, 2, 1 and 0,2 m (the latter was a minimum resolution step for the field NaI detector). Performed measurements showed that the contamination field of 137Cs had a regular structure of polycentric character and exhibited a decrease in spatial variability of contamination with the decrease of the measured area. Repeated measurements of soil contamination in successive years of 2005-2008 along and cross the slopes provided with topographic survey proved the stability of contamination field (r=0, 915, n=121, r=0,912, n=30) and its relation to the meso- and microrelief features. Variation 137Cs activity in lateral direction (along the slopes and thalweg of the hollow)showed a regular character also. In our opinion the regularity in 137Cs spatial structure in the soil cover may result from radionuclide redistribution with the surface and subsurface water flow highly sensitive to the changes in elevation of different scale, and to the slope length and inclination. Cs-137 lateral distribution pattern was likely to reflect alternation of lateral and vertical water mass migration along the slopes. The performed study showing regularity in 137Cs redistribution seems to open new possibilities to develop the deterministic strategy in the study of contamination fields and modeling toxic elements spatial distribution in the soil cover on different scales. The authors are much obliged to Dr. V. Samsonov and Dr. F. Moiseenko for participation in the field work and to S. Kirov for the performance of the laboratory measurement of the soil and plant samples. References 1. Khomutinin, Yu.V., Kashparov, V.A., Zhebrovskaya, E.I., 2001. Optimization of sampling and

  20. Stability-integrated Fuzzy C means segmentation for spatial ...

    Indian Academy of Sciences (India)

    V ROYNA DAISY

    2018-03-16

    Mar 16, 2018 ... clusters and including spatial information to basic Fuzzy C Means clustering are done in .... modify the objective function with Kernel distance function .... spatial information, thus making it sensitive to noise and outliers.

  1. Stability of Einstein static state universe in the spatially flat branemodels

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Kaituo [Department of Physics, Anhui Normal University, Wuhu, Anhui 241000 (China); Wu, Puxun [Center for Nonlinear Science and Department of Physics, Ningbo University, Ningbo, Zhejiang 315211 (China); Synergetic Innovation Center for Quantum Effects and Applications, Hunan Normal University, Changsha, Hunan 410081 (China); Center for High Energy Physics, Peking University, Beijing 100080 (China); Yu, Hongwei, E-mail: hwyu@hunnu.edu.cn [Synergetic Innovation Center for Quantum Effects and Applications, Hunan Normal University, Changsha, Hunan 410081 (China); Center for Nonlinear Science and Department of Physics, Ningbo University, Ningbo, Zhejiang 315211 (China); Luo, Ling-Wei [Institute of Physics, Chiao Tung University, Hsinchu 300, Taiwan (China)

    2016-07-10

    With the assumption that a perfect fluid with a constant equation of state is the only energy component on the brane, we study the stability of Einstein static state solution under homogeneous and inhomogeneous scalar perturbations in both spatially flat Randall–Sundrum (RS) and Shtanov–Sahni (SS) braneworlds. We find that if the perfect fluid has a phantom-like property and the “Weyl fluid” originating from the projection of the bulk Weyl tensor onto the brane behaves like a radiation with positive energy density, the Einstein static state solution is stable in the SS braneworld, but unstable in the RS one. Furthermore, we demonstrate that the static state solution is also stable in the bulk with a timelike extra dimension. Thus, in the model where the extra dimension is timelike, our universe can stay at the Einstein static state past-eternally, which means that the big bang singularity might be resolved successfully by an emergent scenario.

  2. Non Lyapunov stability of the constant spatially developing 1-D gas flow in presence of solutions having strictly positive exponential growth rate

    Science.gov (United States)

    Balint, Stefan; Balint, Agneta M.

    2017-01-01

    Different types of stabilities (global, local) and instabilities (global absolute, local convective) of the constant spatially developing 1-D gas flow are analyzed in the phase space of continuously differentiable functions, endowed with the usual algebraic operations and the topology generated by the uniform convergence on the real axis. For this purpose the Euler equations linearized at the constant flow are used. The Lyapunov stability analysis was presented in [1] and this paper is a continuation of [1].

  3. Spatially resolved Raman spectroscopy study of transformed zones in magnesia-partially-stabilized zirconia

    International Nuclear Information System (INIS)

    Davskardt, R.H.; Veirs, D.K.; Ritchie, R.O.

    1989-01-01

    Raman vibrational spectroscopy provides an effective phase characterization technique in materials systems containing particle dispersions of the tetragonal and monoclinic polymorphs of zirconia, each of which yields a unique Raman spectrum. An investigation is reported to assess a novel, spatially resolved Raman spectroscopy system in the study of transformed zones surrounding cracks in partially stabilized MgO-ZrO 2 (PSZ). The experimental arrangement uses an imaging (two-dimensional) photomultiplier tube to produce a one-dimensional Raman profile of phase compositions along a slitlike laser beam without translation of either the sample or the laser beam and without scanning the spectrometer. Results from phase characterization studies of the size, frontal morphology, and extent of transformation of transformation zones surrounding cracks produced under monotonic and cyclic loading conditions are presented

  4. Citrobacter amalonaticus phytase on the cell surface of Pichia pastoris exhibits high pH stability as a promising potential feed supplement.

    Science.gov (United States)

    Li, Cheng; Lin, Ying; Huang, Yuanyuan; Liu, Xiaoxiao; Liang, Shuli

    2014-01-01

    Phytase expressed and anchored on the cell surface of Pichia pastoris avoids the expensive and time-consuming steps of protein purification and separation. Furthermore, yeast cells with anchored phytase can be used as a whole-cell biocatalyst. In this study, the phytase gene of Citrobacter amalonaticus was fused with the Pichia pastoris glycosylphosphatidylinositol (GPI)-anchored glycoprotein homologue GCW61. Phytase exposed on the cell surface exhibits a high activity of 6413.5 U/g, with an optimal temperature of 60°C. In contrast to secreted phytase, which has an optimal pH of 5.0, phytase presented on the cell surface is characterized by an optimal pH of 3.0. Moreover, our data demonstrate that phytase anchored on the cell surface exhibits higher pH stability than its secreted counterpart. Interestingly, our in vitro digestion experiments demonstrate that phytase attached to the cell surface is a more efficient enzyme than secreted phytase.

  5. Iron Redox Dynamics in Humid Tropical Forest Soils: Carbon Stabilization vs. Degradation?

    Science.gov (United States)

    Hall, S. J.; Silver, W. L.; Hammel, K.

    2015-12-01

    Most terrestrial soils exhibit a patchwork of oxygen (O2) availability that varies over spatial scales of microsites to catenas to landscapes, and over temporal scales of minutes to seasons. Oxygen fluctuations often drive microbial iron (Fe) reduction and abiotic/biotic Fe oxidation at the microsite scale, contributing to anaerobic carbon (C) mineralization and changes in soil physical and chemical characteristics, especially the dissolution and precipitation of short-range ordered Fe phases thought to stabilize C. Thus, O2 fluctuations and Fe redox cycling may have multiple nuanced and opposing impacts on different soil C pools, illustrated by recent findings from Fe-rich Oxisols and Ultisols in the Luquillo Experimental Forest, Puerto Rico. Spatial patterns in surface soil C stocks at the landscape scale correlated strongly (R2 = 0.98) with concentrations of reduced Fe (Fe(II)), reflecting constitutive differences in reducing conditions within and among sites that promote C accumulation in mineral soil horizons. Similarly, turnover times of a decadal-cycling pool of mineral-associated organic matter increased with Fe(II) across a catena, possibly reflecting the role of anaerobic microsites in long-term C stabilization. However, two different indices of short-range order Fe showed highly significant opposing relationships (positive and negative) with spatial variation in soil C concentrations, possibly reflecting a dual role of Fe in driving C stabilization via co-precipitation, and C solubilization and loss following dissimilatory Fe reduction. Consistent with the field data, laboratory incubations demonstrated that redox fluctuations can increase the contribution of biochemically recalcitrant C (lignin) to soil respiration, whereas addition of short-range order Fe dramatically suppressed lignin mineralization but had no impact on bulk soil respiration. Thus, understanding spatial and temporal patterns of Fe redox cycling may provide insight into explaining the

  6. The Relationship Between Postural and Movement Stability.

    Science.gov (United States)

    Feldman, Anatol G

    2016-01-01

    Postural stabilization is provided by stretch reflexes, intermuscular reflexes, and intrinsic muscle properties. Taken together, these posture-stabilizing mechanisms resist deflections from the posture at which balance of muscle and external forces is maintained. Empirical findings suggest that for each muscle, these mechanisms become functional at a specific, spatial threshold-the muscle length or respective joint angle at which motor units begin to be recruited. Empirical data suggest that spinal and supraspinal centers can shift the spatial thresholds for a group of muscles that stabilized the initial posture. As a consequence, the same stabilizing mechanisms, instead of resisting motion from the initial posture, drive the body to another stable posture. In other words by shifting spatial thresholds, the nervous system converts movement resisting to movement-producing mechanisms. It is illustrated that, contrary to conventional view, this control strategy allows the system to transfer body balance to produce locomotion and other actions without loosing stability at any point of them. It also helps orient posture and movement with the direction of gravity. It is concluded that postural and movement stability is provided by a common mechanism.

  7. Stabilizing the thermal lattice Boltzmann method by spatial filtering.

    Science.gov (United States)

    Gillissen, J J J

    2016-10-01

    We propose to stabilize the thermal lattice Boltzmann method by filtering the second- and third-order moments of the collision operator. By means of the Chapman-Enskog expansion, we show that the additional numerical diffusivity diminishes in the low-wavnumber limit. To demonstrate the enhanced stability, we consider a three-dimensional thermal lattice Boltzmann system involving 33 discrete velocities. Filtering extends the linear stability of this thermal lattice Boltzmann method to 10-fold smaller transport coefficients. We further demonstrate that the filtering does not compromise the accuracy of the hydrodynamics by comparing simulation results to reference solutions for a number of standardized test cases, including natural convection in two dimensions.

  8. Probabilistic evaluation method of stability of ground and slope considering spatial randomness of soil properties

    International Nuclear Information System (INIS)

    Ohtori, Yasuki

    2004-01-01

    In the JEAG4601-1987 (Japan Electric Association Guide for earthquake resistance design), either the conventional deterministic method or probabilistic method is used for evaluating the stability of ground foundations and surrounding slopes in nuclear power plants. The deterministic method, in which the soil properties of 'mean ± coefficient x standard deviation' is adopted for the calculations, is generally used in the design stage to data. On the other hand, the probabilistic method, in which the soil properties assume to have probabilistic distributions, is stated as a future method. The deterministic method facilitates the evaluation, however, it is necessary to clarify the relation with the probabilistic method. In this paper, the relationship between the deterministic and the probabilistic methods are investigated. To do that, a simple model that can take into account the dynamic effect of structures and a simplified method for accounting the spatial randomness are proposed and used for the studies. As the results of studies, it is found that the strength of soil properties is most importation factor for the stability of ground structures and the probability below the safety factor evaluated with the soil properties of mean -1.0 x standard deviation' by the deterministic method is of much lower. (author)

  9. Scale dependence of the diversity-stability relationship in a temperate grassland.

    Science.gov (United States)

    Zhang, Yunhai; He, Nianpeng; Loreau, Michel; Pan, Qingmin; Han, Xingguo

    2018-05-01

    A positive relationship between biodiversity and ecosystem stability has been reported in many ecosystems; however, it has yet to be determined whether and how spatial scale affects this relationship. Here, for the first time, we assessed the effects of alpha, beta and gamma diversity on ecosystem stability and the scale dependence of the slope of the diversity-stability relationship.By employing a long-term (33 years) dataset from a temperate grassland, northern China, we calculated the all possible spatial scales with the complete combination from the basic 1-m 2 plots.Species richness was positively associated with ecosystem stability through species asynchrony and overyielding at all spatial scales (1, 2, 3, 4 and 5 m 2 ). Both alpha and beta diversity were positively associated with gamma stability.Moreover, the slope of the diversity-area relationship was significantly higher than that of the stability-area relationship, resulting in a decline of the slope of the diversity-stability relationship with increasing area. Synthesis. With the positive species diversity effect on ecosystem stability from small to large spatial scales, our findings demonstrate the need to maintain a high biodiversity and biotic heterogeneity as insurance against the risks incurred by ecosystems in the face of global environmental changes.

  10. Synchronisation and stability in river metapopulation networks.

    Science.gov (United States)

    Yeakel, J D; Moore, J W; Guimarães, P R; de Aguiar, M A M

    2014-03-01

    Spatial structure in landscapes impacts population stability. Two linked components of stability have large consequences for persistence: first, statistical stability as the lack of temporal fluctuations; second, synchronisation as an aspect of dynamic stability, which erodes metapopulation rescue effects. Here, we determine the influence of river network structure on the stability of riverine metapopulations. We introduce an approach that converts river networks to metapopulation networks, and analytically show how fluctuation magnitude is influenced by interaction structure. We show that river metapopulation complexity (in terms of branching prevalence) has nonlinear dampening effects on population fluctuations, and can also buffer against synchronisation. We conclude by showing that river transects generally increase synchronisation, while the spatial scale of interaction has nonlinear effects on synchronised dynamics. Our results indicate that this dual stability - conferred by fluctuation and synchronisation dampening - emerges from interaction structure in rivers, and this may strongly influence the persistence of river metapopulations. © 2013 John Wiley & Sons Ltd/CNRS.

  11. Gravity stabilizes itself

    International Nuclear Information System (INIS)

    Chakraborty, Sumanta; SenGupta, Soumitra

    2017-01-01

    We show that a possible resolution to the stabilization of an extra spatial dimension (radion) can be obtained solely in the context of gravitational dynamics itself without the necessity of introducing any external stabilizing field. In this scenario the stabilized value of the radion field gets determined in terms of the parameters appearing in the higher curvature gravitational action. Furthermore, the mass of the radion field and its coupling to the standard model fields are found to be in the weak scale implying possible signatures in the TeV scale colliders. Some resulting implications are also discussed. (orig.)

  12. Gravity stabilizes itself

    Energy Technology Data Exchange (ETDEWEB)

    Chakraborty, Sumanta; SenGupta, Soumitra [Indian Association for the Cultivation of Science, Department of Theoretical Physics, Kolkata (India)

    2017-08-15

    We show that a possible resolution to the stabilization of an extra spatial dimension (radion) can be obtained solely in the context of gravitational dynamics itself without the necessity of introducing any external stabilizing field. In this scenario the stabilized value of the radion field gets determined in terms of the parameters appearing in the higher curvature gravitational action. Furthermore, the mass of the radion field and its coupling to the standard model fields are found to be in the weak scale implying possible signatures in the TeV scale colliders. Some resulting implications are also discussed. (orig.)

  13. Comparison of the colloidal stability, bioaccessibility and antioxidant activity of corn protein hydrolysate and sodium caseinate stabilized curcumin nanoparticles.

    Science.gov (United States)

    Wang, Yong-Hui; Yuan, Yang; Yang, Xiao-Quan; Wang, Jin-Mei; Guo, Jian; Lin, Yuan

    2016-07-01

    The aims of this work were to construct corn protein hydrolysate (CPH)-based curcumin nanoparticles (Cur NPs) and to compare the colloidal stability, bioaccessibility and antioxidant activity of the Cur NPs stabilized CPH and sodium caseinate (NaCas) respectively. The results indicated that Cur solubility could be considerably improved after the Cur NPs fabrication. The spectroscopy results demonstrated that the solubilization of Cur should be attributed to its complexation with CPH or NaCas. The Cur NPs exhibited good colloidal stability after 1 week's storage but showed smaller (40 nm) size in CPH than in NaCas (100 nm). After lyophilization, the Cur NPs powders showed good rehydration properties and chemical stability, and compared with NaCas, the size of Cur NPs stabilized by CPH was still smaller. Additionally, the Cur NPs exhibited higher chemical stability against the temperature compared with free Cur, and the CPH could protect Cur from degradation more efficiently. Comparing with NaCas, the Cur NPs stabilized by CPH exhibited better bioaccessibility and antioxidant activity. This study demonstrated that CPH may be better than NaCas in Cur NPs fabrication and it opens up the possibility of using hydrophobic protein hydrolysate to construct the NPs delivery system.

  14. TPGS-Stabilized Curcumin Nanoparticles Exhibit Superior Effect on Carrageenan-Induced Inflammation in Wistar Rat

    Directory of Open Access Journals (Sweden)

    Heni Rachmawati

    2016-08-01

    Full Text Available Curcumin, a hydrophobic polyphenol compound derived from the rhizome of the Curcuma genus, has a wide spectrum of biological and pharmacological applications. Previously, curcumin nanoparticles with different stabilizers had been produced successfully in order to enhance solubility and per oral absorption. In the present study, we tested the anti-inflammatory effect of d-α-Tocopheryl polyethylene glycol 1000 succinate (TPGS-stabilized curcumin nanoparticles in vivo. Lambda-carrageenan (λ-carrageenan was used to induce inflammation in rats; it was given by an intraplantar route and intrapelurally through surgery in the pleurisy test. In the λ-carrageenan-induced edema model, TPGS-stabilized curcumin nanoparticles were given orally one hour before induction and at 0.5, 4.5, and 8.5 h after induction with two different doses (1.8 and 0.9 mg/kg body weight (BW. Sodium diclofenac with a dose of 4.5 mg/kg BW was used as a standard drug. A physical mixture of curcumin-TPGS was also used as a comparison with a higher dose of 60 mg/kg BW. The anti-inflammatory effect was assessed on the edema in the carrageenan-induced paw edema model and by the volume of exudate as well as the number of leukocytes reduced in the pleurisy test. TPGS-stabilized curcumin nanoparticles with lower doses showed better anti-inflammatory effects, indicating the greater absorption capability through the gastrointestinal tract.

  15. Scale dependence of the diversity–stability relationship in a temperate grassland

    Science.gov (United States)

    Zhang, Yunhai; He, Nianpeng; Loreau, Michel; Pan, Qingmin; Han, Xingguo

    2018-01-01

    A positive relationship between biodiversity and ecosystem stability has been reported in many ecosystems; however, it has yet to be determined whether and how spatial scale affects this relationship. Here, for the first time, we assessed the effects of alpha, beta and gamma diversity on ecosystem stability and the scale dependence of the slope of the diversity–stability relationship.By employing a long-term (33 years) dataset from a temperate grassland, northern China, we calculated the all possible spatial scales with the complete combination from the basic 1-m2 plots.Species richness was positively associated with ecosystem stability through species asynchrony and overyielding at all spatial scales (1, 2, 3, 4 and 5 m2). Both alpha and beta diversity were positively associated with gamma stability.Moreover, the slope of the diversity–area relationship was significantly higher than that of the stability–area relationship, resulting in a decline of the slope of the diversity–stability relationship with increasing area.Synthesis. With the positive species diversity effect on ecosystem stability from small to large spatial scales, our findings demonstrate the need to maintain a high biodiversity and biotic heterogeneity as insurance against the risks incurred by ecosystems in the face of global environmental changes. PMID:29725139

  16. A two-locus model of spatially varying stabilizing or directional selection on a quantitative trait.

    Science.gov (United States)

    Geroldinger, Ludwig; Bürger, Reinhard

    2014-06-01

    The consequences of spatially varying, stabilizing or directional selection on a quantitative trait in a subdivided population are studied. A deterministic two-locus two-deme model is employed to explore the effects of migration, the degree of divergent selection, and the genetic architecture, i.e., the recombination rate and ratio of locus effects, on the maintenance of genetic variation. The possible equilibrium configurations are determined as functions of the migration rate. They depend crucially on the strength of divergent selection and the genetic architecture. The maximum migration rates are investigated below which a stable fully polymorphic equilibrium or a stable single-locus polymorphism can exist. Under stabilizing selection, but with different optima in the demes, strong recombination may facilitate the maintenance of polymorphism. However usually, and in particular with directional selection in opposite direction, the critical migration rates are maximized by a concentrated genetic architecture, i.e., by a major locus and a tightly linked minor one. Thus, complementing previous work on the evolution of genetic architectures in subdivided populations subject to diversifying selection, it is shown that concentrated architectures may aid the maintenance of polymorphism. Conditions are obtained when this is the case. Finally, the dependence of the phenotypic variance, linkage disequilibrium, and various measures of local adaptation and differentiation on the parameters is elaborated. Copyright © 2014 The Authors. Published by Elsevier Inc. All rights reserved.

  17. Advanced Techniques for Assessment of Postural and Locomotor Ataxia, Spatial Orientation, and Gaze Stability

    Science.gov (United States)

    Wall, Conrad., III

    1999-01-01

    In addition to adapting to microgravity, major neurovestibular problems of space flight include postflight difficulties with standing, walking, turning corners, and other activities that require stable upright posture and gaze stability. These difficulties inhibit astronauts' ability to stand or escape from their vehicle during emergencies. The long-ter7n goal of the NSBRI is the development of countermeasures to ameliorate the effects of long duration space flight. These countermeasures must be tested with valid and reliable tools. This project aims to develop quantitative, parametric approaches for assessing gaze stability and spatial orientation during normal gait and when gait is perturbed. Two of this year's most important findings concern head fixation distance and ideal trajectory analysis. During a normal cycle of walking the head moves up and down linearly. A simultaneous angular pitching motion of the head keeps it aligned toward an imaginary point in space at a distance of about one meter in front of a subject and along the line of march. This distance is called the head fixation distance. Head fixation distance provides the fundamental framework necessary for understanding the functional significance of the vestibular reflexes that couple head motion to eye motion. This framework facilitates the intelligent design of counter-measures for the effects of exposure to microgravity upon the vestibular ocular reflexes. Ideal trajectory analysis is a simple candidate countermeasure based upon quantifying body sway during repeated up and down stair stepping. It provides one number that estimates the body sway deviation from an ideal sinusoidal body sway trajectory normalized on the subject's height. This concept has been developed with NSBRI funding in less than one year. These findings are explained in more detail below. Compared to assessments of the vestibuo-ocular reflex, analysis of vestibular effects on locomotor function is relatively less well developed

  18. Dynamic stability and bifurcation analysis in fractional thermodynamics

    Science.gov (United States)

    Béda, Péter B.

    2018-02-01

    In mechanics, viscoelasticity was the first field of applications in studying geomaterials. Further possibilities arise in spatial non-locality. Non-local materials were already studied in the 1960s by several authors as a part of continuum mechanics and are still in focus of interest because of the rising importance of materials with internal micro- and nano-structure. When material instability gained more interest, non-local behavior appeared in a different aspect. The problem was concerned to numerical analysis, because then instability zones exhibited singular properties for local constitutive equations. In dynamic stability analysis, mathematical aspects of non-locality were studied by using the theory of dynamic systems. There the basic set of equations describing the behavior of continua was transformed to an abstract dynamic system consisting of differential operators acting on the perturbation field variables. Such functions should satisfy homogeneous boundary conditions and act as indicators of stability of a selected state of the body under consideration. Dynamic systems approach results in conditions for cases, when the differential operators have critical eigenvalues of zero real parts (dynamic stability or instability conditions). When the critical eigenvalues have non-trivial eigenspace, the way of loss of stability is classified as a typical (or generic) bifurcation. Our experiences show that material non-locality and the generic nature of bifurcation at instability are connected, and the basic functions of the non-trivial eigenspace can be used to determine internal length quantities of non-local mechanics. Fractional calculus is already successfully used in thermo-elasticity. In the paper, non-locality is introduced via fractional strain into the constitutive relations of various conventional types. Then, by defining dynamic systems, stability and bifurcation are studied for states of thermo-mechanical solids. Stability conditions and genericity

  19. Spatial Dynamics of Indoor Radio Wideband Channels

    Directory of Open Access Journals (Sweden)

    Hayar Aawatif

    2010-01-01

    Full Text Available The multipath components of superwideband (2–17.2 GHz nonline-of-sight channel responses measured inside several buildings are stable along sections that are 27 cm long on average with a standard deviation of 16 cm. The stability regions of multipath components have an approximately log-normal histogram. An analysis of measured channels that explicitly includes finite spatial areas of visibility of the multipath components is superior to the classic analysis that attributes spatial dynamics to interference of the multipath. The spatial stability of measured responses, that is, the size of the typical area of visibility of each multipath component, decreases as the carrier frequency increases but does not depend on bandwidth. The results offer insight into the nature of the diffuse part of the radio channel.

  20. Spatial Atmospheric Pressure Atomic Layer Deposition of Tin Oxide as an Impermeable Electron Extraction Layer for Perovskite Solar Cells with Enhanced Thermal Stability.

    Science.gov (United States)

    Hoffmann, Lukas; Brinkmann, Kai O; Malerczyk, Jessica; Rogalla, Detlef; Becker, Tim; Theirich, Detlef; Shutsko, Ivan; Görrn, Patrick; Riedl, Thomas

    2018-02-14

    Despite the notable success of hybrid halide perovskite-based solar cells, their long-term stability is still a key-issue. Aside from optimizing the photoactive perovskite, the cell design states a powerful lever to improve stability under various stress conditions. Dedicated electrically conductive diffusion barriers inside the cell stack, that counteract the ingress of moisture and prevent the migration of corrosive halogen species, can substantially improve ambient and thermal stability. Although atomic layer deposition (ALD) is excellently suited to prepare such functional layers, ALD suffers from the requirement of vacuum and only allows for a very limited throughput. Here, we demonstrate for the first time spatial ALD-grown SnO x at atmospheric pressure as impermeable electron extraction layers for perovskite solar cells. We achieve optical transmittance and electrical conductivity similar to those in SnO x grown by conventional vacuum-based ALD. A low deposition temperature of 80 °C and a high substrate speed of 2.4 m min -1 yield SnO x layers with a low water vapor transmission rate of ∼10 -4 gm -2 day -1 (at 60 °C/60% RH). Thereby, in perovskite solar cells, dense hybrid Al:ZnO/SnO x electron extraction layers are created that are the key for stable cell characteristics beyond 1000 h in ambient air and over 3000 h at 60 °C. Most notably, our work of introducing spatial ALD at atmospheric pressure paves the way to the future roll-to-roll manufacturing of stable perovskite solar cells.

  1. The Hall-induced stability of gravitating fluids

    Science.gov (United States)

    Karmakar, P. K.; Goutam, H. P.

    2018-05-01

    We analyze the stability behavior of low-density partially ionized self-gravitating magnetized unbounded dusty plasma fluid in the presence of the Hall diffusion effects (HDEs) in the non-ideal magnetohydrodynamic (MHD) equilibrium framework. The effects of inhomogeneous self-gravity are methodically included in the basic model tapestry. Application of the Fourier plane-wave perturbative treatment decouples the structuration representative parameters into a linear generalized dispersion relation (sextic) in a judicious mean-fluid approximation. The dispersion analysis shows that the normal mode, termed as the gravito-magneto-acoustic (GMA) mode, is drastically modified due to the HDEs. This mode is highly dispersive, and driven unstable by the Hall current resulting from the symmetry-breaking of electrons and ions relative to the magnetic field. The mode feature, which is derived from a modified induction with the positive Hall, is against the ideal MHD. It is further demonstrated that the HDEs play stabilizing roles by supporting the cloud against gravitational collapse. Provided that the HDEs are concurrently switched off, the collapse occurs on the global spatial scale due to enhanced inward accretion of the gravitating dust constituents. It is seen explicitly that the enhanced dust-charge leads to stabilizing effects. Besides, the Hall-induced fluctuations, as propagatory wave modes, exhibit both normal and anomalous dispersions. The reliability checkup of the entailed results as diverse corollaries and special cases are illustratively discussed in the panoptic light of the earlier paradigmatic predictions available in the literature.

  2. Spatial coherence resonance and spatial pattern transition induced by the decrease of inhibitory effect in a neuronal network

    Science.gov (United States)

    Tao, Ye; Gu, Huaguang; Ding, Xueli

    2017-10-01

    Spiral waves were observed in the biological experiment on rat brain cortex with the application of carbachol and bicuculline which can block inhibitory coupling from interneurons to pyramidal neurons. To simulate the experimental spiral waves, a two-dimensional neuronal network composed of pyramidal neurons and inhibitory interneurons was built. By decreasing the percentage of active inhibitory interneurons, the random-like spatial patterns change to spiral waves and to random-like spatial patterns or nearly synchronous behaviors. The spiral waves appear at a low percentage of inhibitory interneurons, which matches the experimental condition that inhibitory couplings of the interneurons were blocked. The spiral waves exhibit a higher order or signal-to-noise ratio (SNR) characterized by spatial structure function than both random-like spatial patterns and nearly synchronous behaviors, which shows that changes of the percentage of active inhibitory interneurons can induce spatial coherence resonance-like behaviors. In addition, the relationship between the coherence degree and the spatial structures of the spiral waves is identified. The results not only present a possible and reasonable interpretation to the spiral waves observed in the biological experiment on the brain cortex with disinhibition, but also reveal that the spiral waves exhibit more ordered degree in spatial patterns.

  3. Postural instability detection: aging and the complexity of spatial-temporal distributional patterns for virtually contacting the stability boundary in human stance.

    Directory of Open Access Journals (Sweden)

    Melissa C Kilby

    Full Text Available Falls among the older population can severely restrict their functional mobility and even cause death. Therefore, it is crucial to understand the mechanisms and conditions that cause falls, for which it is important to develop a predictive model of falls. One critical quantity for postural instability detection and prediction is the instantaneous stability of quiet upright stance based on motion data. However, well-established measures in the field of motor control that quantify overall postural stability using center-of-pressure (COP or center-of-mass (COM fluctuations are inadequate predictors of instantaneous stability. For this reason, 2D COP/COM virtual-time-to-contact (VTC is investigated to detect the postural stability deficits of healthy older people compared to young adults. VTC predicts the temporal safety margin to the functional stability boundary ( =  limits of the region of feasible COP or COM displacement and, therefore, provides an index of the risk of losing postural stability. The spatial directions with increased instability were also determined using quantities of VTC that have not previously been considered. Further, Lempel-Ziv-Complexity (LZC, a measure suitable for on-line monitoring of stability/instability, was applied to explore the temporal structure or complexity of VTC and the predictability of future postural instability based on previous behavior. These features were examined as a function of age, vision and different load weighting on the legs. The primary findings showed that for old adults the stability boundary was contracted and VTC reduced. Furthermore, the complexity decreased with aging and the direction with highest postural instability also changed in aging compared to the young adults. The findings reveal the sensitivity of the time dependent properties of 2D VTC to the detection of postural instability in aging, availability of visual information and postural stance and potential applicability as a

  4. An expanded Notch-Delta model exhibiting long-range patterning and incorporating MicroRNA regulation.

    Directory of Open Access Journals (Sweden)

    Jerry S Chen

    2014-06-01

    Full Text Available Notch-Delta signaling is a fundamental cell-cell communication mechanism that governs the differentiation of many cell types. Most existing mathematical models of Notch-Delta signaling are based on a feedback loop between Notch and Delta leading to lateral inhibition of neighboring cells. These models result in a checkerboard spatial pattern whereby adjacent cells express opposing levels of Notch and Delta, leading to alternate cell fates. However, a growing body of biological evidence suggests that Notch-Delta signaling produces other patterns that are not checkerboard, and therefore a new model is needed. Here, we present an expanded Notch-Delta model that builds upon previous models, adding a local Notch activity gradient, which affects long-range patterning, and the activity of a regulatory microRNA. This model is motivated by our experiments in the ascidian Ciona intestinalis showing that the peripheral sensory neurons, whose specification is in part regulated by the coordinate activity of Notch-Delta signaling and the microRNA miR-124, exhibit a sparse spatial pattern whereby consecutive neurons may be spaced over a dozen cells apart. We perform rigorous stability and bifurcation analyses, and demonstrate that our model is able to accurately explain and reproduce the neuronal pattern in Ciona. Using Monte Carlo simulations of our model along with miR-124 transgene over-expression assays, we demonstrate that the activity of miR-124 can be incorporated into the Notch decay rate parameter of our model. Finally, we motivate the general applicability of our model to Notch-Delta signaling in other animals by providing evidence that microRNAs regulate Notch-Delta signaling in analogous cell types in other organisms, and by discussing evidence in other organisms of sparse spatial patterns in tissues where Notch-Delta signaling is active.

  5. Species dispersal rates alter diversity and ecosystem stability in pond metacommunities.

    Science.gov (United States)

    Howeth, Jennifer G; Leibold, Mathew A

    2010-09-01

    Metacommunity theory suggests that relationships between diversity and ecosystem stability can be determined by the rate of species dispersal among local communities. The predicted relationships, however, may depend upon the relative strength of local environmental processes and disturbance. Here we evaluate the role of dispersal frequency and local predation perturbations in affecting patterns of diversity and stability in pond plankton metacommunities. Pond metacommunities were composed of three mesocosm communities: one of the three communities maintained constant "press" predation from a selective predator, bluegill sunfish (Lepomis macrochirus); the second community maintained "press" conditions without predation; and the third community experienced recurrent "pulsed" predation from bluegill sunfish. The triads of pond communities were connected at either no, low (0.7%/d), or high (20%/d) planktonic dispersal. Richness and composition of zooplankton and stability of plankton biomass and ecosystem productivity were measured at local and regional spatial scales. Dispersal significantly affected diversity such that local and regional biotas at the low dispersal rate maintained the greatest number of species. The unimodal local dispersal-diversity relationship was predator-dependent, however, as selective press predation excluded species regardless of dispersal. Further, there was no effect of dispersal on beta diversity because predation generated local conditions that selected for distinct community assemblages. Spatial and temporal ecosystem stability responded to dispersal frequency but not predation. Low dispersal destabilized the spatial stability of producer biomass but stabilized temporal ecosystem productivity. The results indicate that selective predation can prevent species augmentation from mass effects but has no apparent influence on stability. Dispersal rates, in contrast, can have significant effects on both species diversity and ecosystem

  6. Spatial short-term memory in children with nonverbal learning disabilities: impairment in encoding spatial configuration.

    Science.gov (United States)

    Narimoto, Tadamasa; Matsuura, Naomi; Takezawa, Tomohiro; Mitsuhashi, Yoshinori; Hiratani, Michio

    2013-01-01

    The authors investigated whether impaired spatial short-term memory exhibited by children with nonverbal learning disabilities is due to a problem in the encoding process. Children with or without nonverbal learning disabilities performed a simple spatial test that required them to remember 3, 5, or 7 spatial items presented simultaneously in random positions (i.e., spatial configuration) and to decide if a target item was changed or all items including the target were in the same position. The results showed that, even when the spatial positions in the encoding and probe phases were similar, the mean proportion correct of children with nonverbal learning disabilities was 0.58 while that of children without nonverbal learning disabilities was 0.84. The authors argue with the results that children with nonverbal learning disabilities have difficulty encoding relational information between spatial items, and that this difficulty is responsible for their impaired spatial short-term memory.

  7. Tree-level stability without spacetime fermions: novel examples in string theory

    International Nuclear Information System (INIS)

    Israel, Dan; Niarchos, Vasilis

    2007-01-01

    Is perturbative stability intimately tied with the existence of spacetime fermions in string theory in more than two dimensions? Type 0'B string theory in ten-dimensional flat space is a rare example of a non-tachyonic, non-supersymmetric string theory with a purely bosonic closed string spectrum. However, all known type 0' constructions exhibit massless NSNS tadpoles signaling the fact that we are not expanding around a true vacuum of the theory. In this note, we are searching for perturbatively stable examples of type 0' string theory without massless tadpoles in backgrounds with a spatially varying dilaton. We present two examples with this property in non-critical string theories that exhibit four- and six-dimensional Poincare invariance. We discuss the D-branes that can be embedded in this context and the type of gauge theories that can be constructed in this manner. We also comment on the embedding of these non-critical models in critical string theories and their holographic (Little String Theory) interpretation and propose a general conjecture for the role of asymptotic supersymmetry in perturbative string theory

  8. Residual analysis for spatial point processes

    DEFF Research Database (Denmark)

    Baddeley, A.; Turner, R.; Møller, Jesper

    We define residuals for point process models fitted to spatial point pattern data, and propose diagnostic plots based on these residuals. The techniques apply to any Gibbs point process model, which may exhibit spatial heterogeneity, interpoint interaction and dependence on spatial covariates. Ou...... or covariate effects. Q-Q plots of the residuals are effective in diagnosing interpoint interaction. Some existing ad hoc statistics of point patterns (quadrat counts, scan statistic, kernel smoothed intensity, Berman's diagnostic) are recovered as special cases....

  9. Posture, head stability, and orientation recovery during vestibular regeneration in pigeons.

    Science.gov (United States)

    Dickman, J David; Lim, Insook

    2004-09-01

    Compensatory behavior such as oculomotor, gaze, and postural responses that occur during movement largely depend upon a functioning vestibular system. In the present study, the initial loss and subsequent recovery of postural and head stability in pigeons undergoing vestibular regeneration were examined. Adult pigeons were trained to manipulate a straight run chamber to peck an illuminated key for fluid reward. Six behavioral measures assessing performance, posture, and head stability were quantified. These included run latency, steps (walking), path negotiation (lane changes), gaze saccades, head bobs, and head shakes. Once normative values were obtained for four birds, complete lesion of all receptor cells and denervation of the epithelia in the vestibular endorgans were produced using a single intralabyrinthine application of streptomycin sulfate. Each bird was then tested at specific times during regeneration and the same behavioral measures examined. At 7 days post-streptomycin treatment (PST), all birds exhibited severe postural and head instability, with tremors, head shakes, staggering, and circling predominating. No normal trial runs, walking, gaze saccades, or head bobs were present. Many of these dysfunctions persisted through 3-4 weeks PST. Gradually, tremor and head shakes diminished and were replaced with an increasing number of normal head bobs during steps and gaze saccades. Beginning at 4 weeks PST, but largely inaccurate, was the observed initiation of directed steps, less staggering, and some successful path negotiation. As regeneration progressed, spatial orientation and navigation ability increased and, by 49 days PST, most trials were successful. By 70 days PST, all birds had recovered to pretreatment levels. Thus, it was observed that ataxia must subside, coincident with normalized head and postural stability prior to the recovery of spatial orientation and path navigation recovery. Parallels in recovery were drawn to hair cell regeneration

  10. Slope stability radar for monitoring mine walls

    Science.gov (United States)

    Reeves, Bryan; Noon, David A.; Stickley, Glen F.; Longstaff, Dennis

    2001-11-01

    Determining slope stability in a mining operation is an important task. This is especially true when the mine workings are close to a potentially unstable slope. A common technique to determine slope stability is to monitor the small precursory movements, which occur prior to collapse. The slope stability radar has been developed to remotely scan a rock slope to continuously monitor the spatial deformation of the face. Using differential radar interferometry, the system can detect deformation movements of a rough wall with sub-millimeter accuracy, and with high spatial and temporal resolution. The effects of atmospheric variations and spurious signals can be reduced via signal processing means. The advantage of radar over other monitoring techniques is that it provides full area coverage without the need for mounted reflectors or equipment on the wall. In addition, the radar waves adequately penetrate through rain, dust and smoke to give reliable measurements, twenty-four hours a day. The system has been trialed at three open-cut coal mines in Australia, which demonstrated the potential for real-time monitoring of slope stability during active mining operations.

  11. Controlling the stability of nonlinear optical modes via electromagnetically induced transparency

    Science.gov (United States)

    Zhang, Kun; Liang, Yi-zeng; Lin, Ji; Li, Hui-jun

    2018-02-01

    We propose a scheme to generate and stabilize the high-dimensional spatial solitons via electromagnetically induced transparency (EIT). The system we consider is a resonant atomic ensemble having Λ configuration. We illustrate that under EIT conditions the equation satisfied by the probe field envelope is reduced to a saturable nonlinear Schrödinger equation with the trapping potential, provided by a far-detuned laser field and a random magnetic field. We present high-dimensional soliton solutions exhibiting many interesting characteristics, including diversity (i.e., many different types of soliton solutions can be found, including bright, ring multipole bright, ring multipole defect mode, multiring bright, multiring defect mode, and vortices solitons), the phase transition between bright soliton and higher-order defect modes (i.e., the phase transition can be realized by controlling the nonlinear coefficient or the intensity of the trapping potential), and stability (i.e., various solitons can be stabilized by the Gaussian potential provided by the far detuned laser field, or the random potential provided by the magnetic field). We also find that some solitons are the extension of the linear eigenmode, whereas others entirely derive from the role of nonlinearity. Compared with previous studies, we not only show the diverse soliton solutions in the same system but also find the boundary of the phase transition for the type of solitons. In addition, we present the possibility of using the random potential to stabilize various solitons and vortices.

  12. Spatial Patterns of Inshore Marine Soundscapes.

    Science.gov (United States)

    McWilliam, Jamie

    2016-01-01

    Passive acoustic monitoring was employed to investigate spatial patterns of soundscapes within a marine reserve. High energy level broadband snaps dominated nearly all habitat soundscapes. Snaps, the principal acoustic feature of soundscapes, were primarily responsible for the observed spatial patterns, and soundscapes appeared to retain a level of compositional and configurational stability. In the presence of high-level broadband snaps, soundscape composition was more influenced by geographic location than habitat type. Future research should focus on investigating the spatial patterns of soundscapes across a wider range of coastal and offshore seascapes containing a variety of distinct ecosystems and habitats.

  13. Thermodynamic Model of Spatial Memory

    Science.gov (United States)

    Kaufman, Miron; Allen, P.

    1998-03-01

    We develop and test a thermodynamic model of spatial memory. Our model is an application of statistical thermodynamics to cognitive science. It is related to applications of the statistical mechanics framework in parallel distributed processes research. Our macroscopic model allows us to evaluate an entropy associated with spatial memory tasks. We find that older adults exhibit higher levels of entropy than younger adults. Thurstone's Law of Categorical Judgment, according to which the discriminal processes along the psychological continuum produced by presentations of a single stimulus are normally distributed, is explained by using a Hooke spring model of spatial memory. We have also analyzed a nonlinear modification of the ideal spring model of spatial memory. This work is supported by NIH/NIA grant AG09282-06.

  14. Probabilistic stability analysis: the way forward for stability analysis of sustainable power systems.

    Science.gov (United States)

    Milanović, Jovica V

    2017-08-13

    Future power systems will be significantly different compared with their present states. They will be characterized by an unprecedented mix of a wide range of electricity generation and transmission technologies, as well as responsive and highly flexible demand and storage devices with significant temporal and spatial uncertainty. The importance of probabilistic approaches towards power system stability analysis, as a subsection of power system studies routinely carried out by power system operators, has been highlighted in previous research. However, it may not be feasible (or even possible) to accurately model all of the uncertainties that exist within a power system. This paper describes for the first time an integral approach to probabilistic stability analysis of power systems, including small and large angular stability and frequency stability. It provides guidance for handling uncertainties in power system stability studies and some illustrative examples of the most recent results of probabilistic stability analysis of uncertain power systems.This article is part of the themed issue 'Energy management: flexibility, risk and optimization'. © 2017 The Author(s).

  15. Immersive Exhibitions

    DEFF Research Database (Denmark)

    Achiam, Marianne

    2015-01-01

    The immersive exhibition is a specialized exhibition genre in museums, which creates the illusion of time and place by representing key characteristics of a reference world and by integrating the visitor in this three-dimensionally reconstructed world (Mortensen 2010). A successful representation...... of the reference world depends on three criteria: whether the exhibition is staged as a coherent whole with all the displayed objects supporting the representation, whether the visitor is integrated as a component of the exhibition, and whether the content and message of the exhibition become dramatized...

  16. Controllable Spatial Configuration on Cathode Interface for Enhanced Photovoltaic Performance and Device Stability.

    Science.gov (United States)

    Li, Jiangsheng; Duan, Chenghao; Wang, Ning; Zhao, Chengjie; Han, Wei; Jiang, Li; Wang, Jizheng; Zhao, Yingjie; Huang, Changshui; Jiu, Tonggang

    2018-05-08

    The molecular structure of cathode interface modification materials can affect the surface morphology of the active layer and key electron transfer processes occurring at the interface of polymer solar cells in inverted structures mostly due to the change of molecular configuration. To investigate the effects of spatial configuration of the cathode interfacial modification layer on polymer solar cells device performances, we introduced two novel organic ionic salts (linear NS2 and three-dimensional (3D) NS4) combined with the ZnO film to fabricate highly efficient inverted solar cells. Both organic ionic salts successfully decreased the surface traps of the ZnO film and made its work function more compatible. Especially NS4 in three-dimensional configuration increased the electron mobility and extraction efficiency of the interfacial film, leading to a significant improvement of device performance. Power conversion efficiency (PCE) of 10.09% based on NS4 was achieved. Moreover, 3D interfacial modification could retain about 92% of its initial PCE over 160 days. It is proposed that 3D interfacial modification retards the element penetration-induced degradation without impeding the electron transfer from the active layer to the ZnO film, which significantly improves device stability. This indicates that inserting three-dimensional organic ionic salt is an efficient strategy to enhance device performance.

  17. Spatial synchrony in cisco recruitment

    Science.gov (United States)

    Myers, Jared T.; Yule, Daniel L.; Jones, Michael L.; Ahrenstorff, Tyler D.; Hrabik, Thomas R.; Claramunt, Randall M.; Ebener, Mark P.; Berglund, Eric K.

    2015-01-01

    We examined the spatial scale of recruitment variability for disparate cisco (Coregonus artedi) populations in the Great Lakes (n = 8) and Minnesota inland lakes (n = 4). We found that the scale of synchrony was approximately 400 km when all available data were utilized; much greater than the 50-km scale suggested for freshwater fish populations in an earlier global analysis. The presence of recruitment synchrony between Great Lakes and inland lake cisco populations supports the hypothesis that synchronicity is driven by climate and not dispersal. We also found synchrony in larval densities among three Lake Superior populations separated by 25–275 km, which further supports the hypothesis that broad-scale climatic factors are the cause of spatial synchrony. Among several candidate climate variables measured during the period of larval cisco emergence, maximum wind speeds exhibited the most similar spatial scale of synchrony to that observed for cisco. Other factors, such as average water temperatures, exhibited synchrony on broader spatial scales, which suggests they could also be contributing to recruitment synchrony. Our results provide evidence that abiotic factors can induce synchronous patterns of recruitment for populations of cisco inhabiting waters across a broad geographic range, and show that broad-scale synchrony of recruitment can occur in freshwater fish populations as well as those from marine systems.

  18. Endogenous spatial attention: evidence for intact functioning in adults with autism

    Science.gov (United States)

    Grubb, Michael A.; Behrmann, Marlene; Egan, Ryan; Minshew, Nancy J.; Carrasco, Marisa; Heeger, David J.

    2012-01-01

    Lay Abstract Attention allows us to selectively process the vast amount of information with which we are confronted. Focusing on a certain location of the visual scene (visual spatial attention) enables the prioritization of some aspects of information while ignoring others. Rapid manipulation of the attention field (i.e., the location and spread of visual spatial attention) is a critical aspect of human cognition, and previous research on spatial attention in individuals with autism spectrum disorders (ASD) has produced inconsistent results. In a series of three experiments, we evaluated claims in the literature that individuals with ASD exhibit a deficit in voluntarily controlling the deployment and size of the spatial attention field. We measured how well participants perform a visual discrimination task (accuracy) and how quickly they do so (reaction time), with and without spatial uncertainty (i.e., the lack of predictability concerning the spatial position of the upcoming stimulus). We found that high–functioning adults with autism exhibited slower reactions times overall with spatial uncertainty, but the effects of attention on performance accuracies and reaction times were indistinguishable between individuals with autism and typically developing individuals, in all three experiments. These results provide evidence of intact endogenous spatial attention function in high–functioning adults with ASD, suggesting that atypical endogenous spatial attention cannot be a latent characteristic of autism in general. Scientific Abstract Rapid manipulation of the attention field (i.e., the location and spread of visual spatial attention) is a critical aspect of human cognition, and previous research on spatial attention in individuals with autism spectrum disorders (ASD) has produced inconsistent results. In a series of three psychophysical experiments, we evaluated claims in the literature that individuals with ASD exhibit a deficit in voluntarily controlling the

  19. Dispersion stability of thermal nanofluids

    Directory of Open Access Journals (Sweden)

    Fan Yu

    2017-10-01

    Full Text Available Thermal nanofluids, the engineered fluids with dispersed functional nanoparticles, have exhibited extraordinary thermophysical properties and added functionalities, and thus have enabled a broad range of important applications. The poor dispersion stability of thermal nanofluids, however, has been considered as a long-existing issue that limits their further development and practical application. This review overviews the recent efforts and progresses in improving the dispersion stability of thermal nanofluids such as mechanistic understanding of dispersion behavior of nanofluids, examples of both water-based and oil-based nanofluids, strategies to stabilize nanofluids, and characterization techniques for dispersion behavior of nanofluids. Finally, on-going research needs, and possible solutions to research challenges and future research directions in exploring stably dispersed thermal nanofluids are discussed. Keywords: Thermal nanofluids, Dispersion, Aggregation, Electrostatic stabilization, Steric stabilization

  20. Autonomous informational stability in connective tissues.

    Science.gov (United States)

    Brand, R A

    1992-02-01

    No coherent theories currently explain connective tissue stability (i.e. 'memory') as well as spatial and temporal adaptability in the face of continual flux of its constituents. Furthermore, explanations of stability based exclusively upon DNA raise certain inherent problems, particularly with the spatial concordance of somatic tissues. As an alternative explanation, it is hypothesized that while connective tissue cells produce extracellular protein precursors through DNA-dependent processes, the assembly, location, orientation and configuration of the extracellular macromolecules as well as their degree of cell attachment depend primarily upon local micro-environmental conditions and/or self-organization rather than strictly cellular processes. The resulting extracellular matrix (ECM) serves as a time- and spatially-variable filter about each cell to afford a relatively consistent micro-environment for all similar cells, regardless of the more variable macro-environment. By insuring a consistent set of signals to the cell, the filter provides a non-genetic memory complementary to genetic memory. The half-lives of constituent molecules define the duration of the filter, allowing the filter to adapt to new environmental demands, yet to maintain a consistent milieu for the cell. The cell/matrix construct permits local, self-optimizing, non-deterministic tissue autonomy obviating the need to postulate certain intricate mechanisms coordinating spatial morphology and temporal behavior.

  1. Thermodynamic stability criteria for a quantum memory based on stabilizer and subsystem codes

    International Nuclear Information System (INIS)

    Chesi, Stefano; Loss, Daniel; Bravyi, Sergey; Terhal, Barbara M

    2010-01-01

    We discuss several thermodynamic criteria that have been introduced to characterize the thermal stability of a self-correcting quantum memory. We first examine the use of symmetry-breaking fields in analyzing the properties of self-correcting quantum memories in the thermodynamic limit; we show that the thermal expectation values of all logical operators vanish for any stabilizer and any subsystem code in any spatial dimension. On the positive side, we generalize the results of Alicki et al to obtain a general upper bound on the relaxation rate of a quantum memory at nonzero temperature, assuming that the quantum memory interacts via a Markovian master equation with a thermal bath. This upper bound is applicable to quantum memories based on either stabilizer or subsystem codes.

  2. Two-Dimensional Spatial Solitons in Nematic Liquid Crystals

    International Nuclear Information System (INIS)

    Zhong Weiping; Xie Ruihua; Goong Chen; Belic, Milivoj; Yang Zhengping

    2009-01-01

    We study the propagation of spatial solitons in nematic liquid crystals, using the self-similar method. Analytical solutions in the form of self-similar solitons are obtained exactly. We confirm the stability of these solutions by direct numerical simulation, and find that the stable spatial solitons can exist in various forms, such as Gaussian solitons, radially symmetric solitons, multipole solitons, and soliton vortices.

  3. Spatial Memory in Captive Giant Anteaters (Myrmecophaga tridactyla

    Directory of Open Access Journals (Sweden)

    Stephanie M. Allard

    2014-08-01

    Full Text Available The type of learning exhibited during foraging has been studied in a large number of species. Species that feed on food sources that temporally vary in quality could be well suited for exhibiting evidence of spatial learning. The foraging strategies of captive giant anteaters were examined using an experimental foraging task. Two giant anteaters were exposed to a modified radial arm maze in order to determine whether or not they would demonstrate evidence of spatial learning. Both subjects demonstrated significant improvement in performance by visiting baited feeders more consistently across learning trials. A disruption in performance occurred when the task was reversed, indicating that giant anteaters may use spatial learning to locate food sources. Obtaining a more sound understanding of the cognitive abilities of giant anteaters may help to enhance their welfare in captive settings.

  4. Temporal acceleration of spatially distributed kinetic Monte Carlo simulations

    International Nuclear Information System (INIS)

    Chatterjee, Abhijit; Vlachos, Dionisios G.

    2006-01-01

    The computational intensity of kinetic Monte Carlo (KMC) simulation is a major impediment in simulating large length and time scales. In recent work, an approximate method for KMC simulation of spatially uniform systems, termed the binomial τ-leap method, was introduced [A. Chatterjee, D.G. Vlachos, M.A. Katsoulakis, Binomial distribution based τ-leap accelerated stochastic simulation, J. Chem. Phys. 122 (2005) 024112], where molecular bundles instead of individual processes are executed over coarse-grained time increments. This temporal coarse-graining can lead to significant computational savings but its generalization to spatially lattice KMC simulation has not been realized yet. Here we extend the binomial τ-leap method to lattice KMC simulations by combining it with spatially adaptive coarse-graining. Absolute stability and computational speed-up analyses for spatial systems along with simulations provide insights into the conditions where accuracy and substantial acceleration of the new spatio-temporal coarse-graining method are ensured. Model systems demonstrate that the r-time increment criterion of Chatterjee et al. obeys the absolute stability limit for values of r up to near 1

  5. Exhibit Engineering

    DEFF Research Database (Denmark)

    Mortensen, Marianne Foss

    Science museums define the objectives of their exhibitions in terms of visitor learning outcomes. Yet, exhibit designers lack theoretical and empirical research findings on which to base the creation of such educational environments. Here, this shortcoming is addressed through the development...... of tools and processes to guide the design of educational science exhibits. The guiding paradigm for this development is design-based research, which is characterised by an iterative cycle of design, enactment, and analysis. In the design phase, an educational intervention is planned and carried out based...... on the generation of theoretical ideas for exhibit design is offered in a fourth and parallel research undertaking, namely the application of the notion of cultural border-crossing to a hypothetical case of exhibit design....

  6. Imaging magnetisation dynamics in nano-contact spin-torque vortex oscillators exhibiting gyrotropic mode splitting

    Science.gov (United States)

    Keatley, Paul Steven; Redjai Sani, Sohrab; Hrkac, Gino; Majid Mohseni, Seyed; Dürrenfeld, Philipp; Åkerman, Johan; Hicken, Robert James

    2017-04-01

    Nano-contact spin-torque vortex oscillators (STVOs) are anticipated to find application as nanoscale sources of microwave emission in future technological applications. Presently the output power and phase stability of individual STVOs are not competitive with existing oscillator technologies. Synchronisation of multiple nano-contact STVOs via magnetisation dynamics has been proposed to enhance the microwave emission. The control of device-to-device variations, such as mode splitting of the microwave emission, is essential if multiple STVOs are to be successfully synchronised. In this work a combination of electrical measurements and time-resolved scanning Kerr microscopy (TRSKM) was used to demonstrate how mode splitting in the microwave emission of STVOs was related to the magnetisation dynamics that are generated. The free-running STVO response to a DC current only was used to identify devices and bias magnetic field configurations for which single and multiple modes of microwave emission were observed. Stroboscopic Kerr images were acquired by injecting a small amplitude RF current to phase lock the free-running STVO response. The images showed that the magnetisation dynamics of a multimode device with moderate splitting could be controlled by the injected RF current so that they exhibit similar spatial character to that of a single mode. Significant splitting was found to result from a complicated equilibrium magnetic state that was observed in Kerr images as irregular spatial characteristics of the magnetisation dynamics. Such dynamics were observed far from the nano-contact and so their presence cannot be detected in electrical measurements. This work demonstrates that TRSKM is a powerful tool for the direct observation of the magnetisation dynamics generated by STVOs that exhibit complicated microwave emission. Characterisation of such dynamics outside the nano-contact perimeter permits a deeper insight into the requirements for optimal phase-locking of

  7. Photochemical stability of electrochromic polymers and devices

    DEFF Research Database (Denmark)

    Jensen, Jacob; Madsen, Morten Vesterager; Krebs, Frederik C

    2013-01-01

    The stability of fully printed flexible organic electrochromics based on 11 different conjugated polymers is explored from the fundamental chemical degradation level to the operational device level. The photochemical stability of the electrochromic polymers (ECPs) is studied enabling an analysis ...... based on flexible barrier substrates exhibit increased stability and are indeed viable in devices such as shading elements, light management systems, displays with low switching speed requirements and signage. © 2013 The Royal Society of Chemistry....

  8. Role of high-order aberrations in senescent changes in spatial vision

    Energy Technology Data Exchange (ETDEWEB)

    Elliot, S; Choi, S S; Doble, N; Hardy, J L; Evans, J W; Werner, J S

    2009-01-06

    The contributions of optical and neural factors to age-related losses in spatial vision are not fully understood. We used closed-loop adaptive optics to test the visual benefit of correcting monochromatic high-order aberrations (HOAs) on spatial vision for observers ranging in age from 18-81 years. Contrast sensitivity was measured monocularly using a two-alternative forced choice (2AFC) procedure for sinusoidal gratings over 6 mm and 3 mm pupil diameters. Visual acuity was measured using a spatial 4AFC procedure. Over a 6 mm pupil, young observers showed a large benefit of AO at high spatial frequencies, whereas older observers exhibited the greatest benefit at middle spatial frequencies, plus a significantly larger increase in visual acuity. When age-related miosis is controlled, young and old observers exhibited a similar benefit of AO for spatial vision. An increase in HOAs cannot account for the complete senescent decline in spatial vision. These results may indicate a larger role of additional optical factors when the impact of HOAs is removed, but also lend support for the importance of neural factors in age-related changes in spatial vision.

  9. Spatial structure of neuropeptide allatostatin-4

    International Nuclear Information System (INIS)

    Veliyeva, L.I.; Aliyev, E.Z.

    2011-01-01

    By method of conformational analysis there was determined the spatial structure of neuropeptide allatostatin-4 belonging to allatostatins family. On the basic of value of intramolecular conformational energy calculation was conducted quantitative assessment of the stability of molecule's possible conformational status in dipolar medium terms

  10. Ecosystem stability in space: α, β and γ variability.

    Science.gov (United States)

    Wang, Shaopeng; Loreau, Michel

    2014-08-01

    The past two decades have seen great progress in understanding the mechanisms of ecosystem stability in local ecological systems. There is, however, an urgent need to extend existing knowledge to larger spatial scales to match the scale of management and conservation. Here, we develop a general theoretical framework to study the stability and variability of ecosystems at multiple scales. Analogously to the partitioning of biodiversity, we propose the concepts of alpha, beta and gamma variability. Gamma variability at regional (metacommunity) scale can be partitioned into local alpha variability and spatial beta variability, either multiplicatively or additively. On average, variability decreases from local to regional scales, which creates a negative variability-area relationship. Our partitioning framework suggests that mechanisms of regional ecosystem stability can be understood by investigating the influence of ecological factors on alpha and beta variability. Diversity can provide insurance effects at the various levels of variability, thus generating alpha, beta and gamma diversity-stability relationships. As a consequence, the loss of biodiversity and habitat impairs ecosystem stability at the regional scale. Overall, our framework enables a synthetic understanding of ecosystem stability at multiple scales and has practical implications for landscape management. © 2014 John Wiley & Sons Ltd/CNRS.

  11. Weight Multispectral Reconstruction Strategy for Enhanced Reconstruction Accuracy and Stability With Cerenkov Luminescence Tomography.

    Science.gov (United States)

    Hongbo Guo; Xiaowei He; Muhan Liu; Zeyu Zhang; Zhenhua Hu; Jie Tian

    2017-06-01

    Cerenkov luminescence tomography (CLT) provides a novel technique for 3-D noninvasive detection of radiopharmaceuticals in living subjects. However, because of the severe scattering of Cerenkov light, the reconstruction accuracy and stability of CLT is still unsatisfied. In this paper, a modified weight multispectral CLT (wmCLT) reconstruction strategy was developed which split the Cerenkov radiation spectrum into several sub-spectral bands and weighted the sub-spectral results to obtain the final result. To better evaluate the property of the wmCLT reconstruction strategy in terms of accuracy, stability and practicability, several numerical simulation experiments and in vivo experiments were conducted and the results obtained were compared with the traditional multispectral CLT (mCLT) and hybrid-spectral CLT (hCLT) reconstruction strategies. The numerical simulation results indicated that wmCLT strategy significantly improved the accuracy of Cerenkov source localization and intensity quantitation and exhibited good stability in suppressing noise in numerical simulation experiments. And the comparison of the results achieved from different in vivo experiments further indicated significant improvement of the wmCLT strategy in terms of the shape recovery of the bladder and the spatial resolution of imaging xenograft tumors. Overall the strategy reported here will facilitate the development of nuclear and optical molecular tomography in theoretical study.

  12. Power distribution effects on boiling water reactor stability

    International Nuclear Information System (INIS)

    Damiano, B.; March-Leuba, J.

    1989-01-01

    The work presented in this paper deals with the effects of spatial power distributions on the stability of boiling water reactors (BWRs). It is shown that a conservative power distribution exists for which the stability is minimal. These results are relevant because they imply that bounding stability calculations are possible and, thus, a worst-possible scenario may be defined for a particular BWR geometry. These bounding calculations may, then, be used to determine the maximum expected limit-cycle peak powers

  13. Boris push with spatial stepping

    International Nuclear Information System (INIS)

    Penn, G; Stoltz, P H; Cary, J R; Wurtele, J

    2003-01-01

    The Boris push is commonly used in plasma physics simulations because of its speed and stability. It is second-order accurate, requires only one field evaluation per time step, and has good conservation properties. However, for accelerator simulations it is convenient to propagate particles in z down a changing beamline. A 'spatial Boris push' algorithm has been developed which is similar to the Boris push but uses a spatial coordinate as the independent variable, instead of time. This scheme is compared to the fourth-order Runge-Kutta algorithm, for two simplified muon beam lattices: a uniform solenoid field, and a 'FOFO' lattice where the solenoid field varies sinusoidally along the axis. Examination of the canonical angular momentum, which should be conserved in axisymmetric systems, shows that the spatial Boris push improves accuracy over long distances

  14. Numerical Computation of Detonation Stability

    KAUST Repository

    Kabanov, Dmitry

    2018-01-01

    Then we investigate the Fickett’s detonation analogue coupled with a particular reaction-rate expression. In addition to the linear stability analysis of this model, we demonstrate that it exhibits rich nonlinear dynamics with multiple bifurcations and chaotic behavior.

  15. Technology Exhibition

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1979-09-15

    Linked to the 25th Anniversary celebrations, an exhibition of some of CERN's technological achievements was opened on 22 June. Set up in a new 600 m{sup 2} Exhibition Hall on the CERN site, the exhibition is divided into eight technology areas — magnets, vacuum, computers and data handling, survey and alignment, radiation protection, beam monitoring and handling, detectors, and workshop techniques.

  16. Existence and stability of periodic solutions for a delayed prey-predator model with diffusion effects

    Directory of Open Access Journals (Sweden)

    Hongwei Liang

    2016-01-01

    Full Text Available Existence and stability of spatially periodic solutions for a delay prey-predator diffusion system are concerned in this work. We obtain that the system can generate the spatially nonhomogeneous periodic solutions when the diffusive rates are suitably small. This result demonstrates that the diffusion plays an important role on deriving the complex spatiotemporal dynamics. Meanwhile, the stability of the spatially periodic solutions is also studied. Finally, in order to verify our theoretical results, some numerical simulations are also included.

  17. Stability in the metamemory realism of eyewitness confidence judgments.

    Science.gov (United States)

    Buratti, Sandra; Allwood, Carl Martin; Johansson, Marcus

    2014-02-01

    The stability of eyewitness confidence judgments over time in regard to their reported memory and accuracy of these judgments is of interest in forensic contexts because witnesses are often interviewed many times. The present study investigated the stability of the confidence judgments of memory reports of a witnessed event and of the accuracy of these judgments over three occasions, each separated by 1 week. Three age groups were studied: younger children (8-9 years), older children (10-11 years), and adults (19-31 years). A total of 93 participants viewed a short film clip and were asked to answer directed two-alternative forced-choice questions about the film clip and to confidence judge each answer. Different questions about details in the film clip were used on each of the three test occasions. Confidence as such did not exhibit stability over time on an individual basis. However, the difference between confidence and proportion correct did exhibit stability across time, in terms of both over/underconfidence and calibration. With respect to age, the adults and older children exhibited more stability than the younger children for calibration. Furthermore, some support for instability was found with respect to the difference between the average confidence level for correct and incorrect answers (slope). Unexpectedly, however, the younger children's slope was found to be more stable than the adults. Compared to the previous research, the present study's use of more advanced statistical methods provides a more nuanced understanding of the stability of confidence judgments in the eyewitness reports of children and adults.

  18. Stability analysis of spatially invariant systems with event-triggered communication

    NARCIS (Netherlands)

    Heijmans, S.H.J.; Dolk, V.S.; Borgers, D.P.; Heemels, W.P.M.H.

    2016-01-01

    In this paper we analyze spatially invariant inter-connections consisting of a (finite) number of subsystems that use packet-based communication networks for the exchange of information. An example of such an interconnected system is the platoon of vehicles that uses cooperative control to drive

  19. Ultrahigh stability of atomically thin metallic glasses

    Energy Technology Data Exchange (ETDEWEB)

    Cao, C. R.; Huang, K. Q.; Zhao, N. J.; Sun, Y. T.; Bai, H. Y.; Gu, L., E-mail: l.gu@iphy.ac.cn, E-mail: dzheng@iphy.ac.cn, E-mail: whw@iphy.ac.cn; Zheng, D. N., E-mail: l.gu@iphy.ac.cn, E-mail: dzheng@iphy.ac.cn, E-mail: whw@iphy.ac.cn; Wang, W. H., E-mail: l.gu@iphy.ac.cn, E-mail: dzheng@iphy.ac.cn, E-mail: whw@iphy.ac.cn [Institute of Physics, Chinese Academy of Sciences, Beijing 100190 (China)

    2014-07-07

    We report the fabrication and study of thermal stability of atomically thin ZrCu-based metallic glass films. The ultrathin films exhibit striking dynamic properties, ultrahigh thermal stability, and unique crystallization behavior with discrete crystalline nanoparticles sizes. The mechanisms for the remarkable high stability and crystallization behaviors are attributed to the dewetting process of the ultrathin film. We demonstrated a promising avenue for understanding some fundamental issues such as glassy structure, crystallization, deformation, and glass formation through atomic resolution imaging of the two dimensional like metallic glasses.

  20. Biodiversity, productivity, and the spatial insurance hypothesis revisited

    Science.gov (United States)

    Shanafelt, David W.; Dieckmann, Ulf; Jonas, Matthias; Franklin, Oskar; Loreau, Michel; Perrings, Charles

    2015-01-01

    Accelerating rates of biodiversity loss have led ecologists to explore the effects of species richness on ecosystem functioning and the flow of ecosystem services. One explanation of the relationship between biodiversity and ecosystem functioning lies in the spatial insurance hypothesis, which centers on the idea that productivity and stability increase with biodiversity in a temporally varying, spatially heterogeneous environment. However, there has been little work on the impact of dispersal where environmental risks are more or less spatially correlated, or where dispersal rates are variable. In this paper, we extend the original Loreau model to consider stochastic temporal variation in resource availability, which we refer to as “environmental risk,” and heterogeneity in species dispersal rates. We find that asynchronies across communities and species provide community-level stabilizing effects on productivity, despite varying levels of species richness. Although intermediate dispersal rates play a role in mitigating risk, they are less effective in insuring productivity against global (metacommunity-level) than local (individual community-level) risks. These results are particularly interesting given the emergence of global sources of risk such as climate change or the closer integration of world markets. Our results offer deeper insights into the Loreau model and new perspectives on the effectiveness of spatial insurance in the face of environmental risks. PMID:26100182

  1. Spatial-temporal variability of soil water content in a cropland-shelterbelt-desert site in an arid inland river basin of Northwest China

    Science.gov (United States)

    Shen, Qin; Gao, Guangyao; Hu, Wei; Fu, Bojie

    2016-09-01

    Knowledge of the spatial-temporal variability of soil water content (SWC) is critical for understanding a range of hydrological processes. In this study, the spatial variance and temporal stability of SWC were investigated in a cropland-shelterbelt-desert site at the oasis-desert ecotone in the middle of the Heihe River Basin, China. The SWC was measured on 65 occasions to a depth of 2.8 m at 45 locations during two growing seasons from 2012 to 2013. The standard deviation of the SWC versus the mean SWC exhibited a convex upward relationship in the shelterbelt with the greatest spatial variation at the SWC of around 22.0%, whereas a linearly increasing relationship was observed for the cropland, desert, and land use pattern. The standard deviation of the relative difference was positively linearly correlated with the SWC (p < 0.05) for the land use pattern, whereas such a relationship was not found in the three land use types. The spatial pattern of the SWC was more time stable for the land use pattern, followed by desert, shelterbelt, and cropland. The spatial pattern of SWC changed dramatically among different soil layers. The locations representing the mean SWC varied with the depth, and no location could represent the whole soil profile due to different soil texture, root distribution and irrigation management. The representative locations of each soil layer could be used to estimate the mean SWC well. The statistics of temporal stability of the SWC could be presented equally well with a low frequency of observation (30-day interval) as with a high frequency (5-day interval). Sampling frequency had little effect on the selection of the representative locations of the field mean SWC. This study provides useful information for designing the optimal strategy for sampling SWC at the oasis-desert ecotone in the arid inland river basin.

  2. Stabilization of the wheel running phenotype in mice.

    Science.gov (United States)

    Bowen, Robert S; Cates, Brittany E; Combs, Eric B; Dillard, Bryce M; Epting, Jessica T; Foster, Brittany R; Patterson, Shawnee V; Spivey, Thomas P

    2016-03-01

    Increased physical activity is well known to improve health and wellness by modifying the risks for many chronic diseases. Rodent wheel running behavior is a beneficial surrogate model to evaluate the biology of daily physical activity in humans. Upon initial exposure to a running wheel, individual mice differentially respond to the experience, which confounds the normal activity patterns exhibited in this otherwise repeatable phenotype. To promote phenotypic stability, a minimum seven-day (or greater) acclimation period is utilized. Although phenotypic stabilization is achieved during this 7-day period, data to support acclimation periods of this length are not currently available in the literature. The purpose of this project is to evaluate the wheel running response in C57BL/6j mice immediately following exposure to a running wheel. Twenty-eight male and thirty female C57BL/6j mice (Jackson Laboratory, Bar Harbor, ME) were acquired at eight weeks of age and were housed individually with free access to running wheels. Wheel running distance (km), duration (min), and speed (m∙min(-1)) were measured daily for fourteen days following initial housing. One-way ANOVAs were used to evaluate day-to-day differences in each wheel running character. Limits of agreement and mean difference statistics were calculated between days 1-13 (acclimating) and day 14 (acclimated) to assess day-to-day agreement between each parameter. Wheel running distance (males: F=5.653, p=2.14 × 10(-9); females: F=8.217, p=1.20 × 10(-14)), duration (males: F=2.613, p=0.001; females: F=4.529, p=3.28 × 10(-7)), and speed (males: F=7.803, p=1.22 × 10(-13); females: F=13.140, p=2.00 × 10(-16)) exhibited day-to-day differences. Tukey's HSD post-hoc testing indicated differences between early (males: days 1-3; females: days 1-6) and later (males: days >3; females: days >6) wheel running periods in distance and speed. Duration only exhibited an anomalous difference between wheel running on day 13

  3. Noisy transcription factor NF-¿B oscillations stabilize and sensitize cytokine signaling in space

    DEFF Research Database (Denmark)

    Gangstad, S.W.; Feldager, C.W.; Juul, Jeppe Søgaard

    2013-01-01

    NF-¿B is a major transcription factor mediating inflammatory response. In response to a pro-inflammatory stimulus, it exhibits a characteristic response - a pulse followed by noisy oscillations in concentrations of considerably smaller amplitude. NF-¿B is an important mediator of cellular...... amplitude has not been addressed. We use a cellular automaton model to address these issues in the context of spatially distributed communicating cells. We find that noisy secondary oscillations stabilize concentric wave patterns, thus improving signal quality. Furthermore, both lower secondary amplitude...... as well as noise in the oscillation period might be working against chronic inflammation, the state of self-sustained and stimulus-independent excitations. Our findings suggest that the characteristic irregular secondary oscillations of lower amplitude are not accidental. On the contrary, they might have...

  4. DNA methylation regulates neurophysiological spatial representation in memory formation

    Directory of Open Access Journals (Sweden)

    Eric D. Roth

    2015-04-01

    Full Text Available Epigenetic mechanisms including altered DNA methylation are critical for altered gene transcription subserving synaptic plasticity and the retention of learned behavior. Here, we tested the idea that one role for activity-dependent altered DNA methylation is stabilization of cognition-associated hippocampal place cell firing in response to novel place learning. We observed that a behavioral protocol (spatial exploration of a novel environment known to induce hippocampal place cell remapping resulted in alterations of hippocampal Bdnf DNA methylation. Further studies using neurophysiological in vivo single-unit recordings revealed that pharmacological manipulations of DNA methylation decreased long-term but not short-term place field stability. Together, our data highlight a role for DNA methylation in regulating neurophysiological spatial representation and memory formation.

  5. DNA methylation regulates neurophysiological spatial representation in memory formation.

    Science.gov (United States)

    Roth, Eric D; Roth, Tania L; Money, Kelli M; SenGupta, Sonda; Eason, Dawn E; Sweatt, J David

    2015-04-01

    Epigenetic mechanisms including altered DNA methylation are critical for altered gene transcription subserving synaptic plasticity and the retention of learned behavior. Here we tested the idea that one role for activity-dependent altered DNA methylation is stabilization of cognition-associated hippocampal place cell firing in response to novel place learning. We observed that a behavioral protocol (spatial exploration of a novel environment) known to induce hippocampal place cell remapping resulted in alterations of hippocampal Bdnf DNA methylation. Further studies using neurophysiological in vivo single unit recordings revealed that pharmacological manipulations of DNA methylation decreased long-term but not short-term place field stability. Together our data highlight a role for DNA methylation in regulating neurophysiological spatial representation and memory formation.

  6. Preparation of [In-111]-labeled-DTPA-bombesin conjugates at high specific activity and stability: Evaluation of labeling parameters and potential stabilizers

    Energy Technology Data Exchange (ETDEWEB)

    Pujatti, P.B., E-mail: pujatti.pb@gmail.com [Directory of Radiopharmacy, Nuclear and Energy Research Institute (IPEN/CNEN), Av. Prof. Lineu Prestes, 2242 - Cidade Universitaria da USP - Butanta, Sao Paulo - SP - Brazil - CEP: 05508-000 (Brazil); Massicano, A.V.F.; Mengatti, J.; Araujo, E.B. de [Directory of Radiopharmacy, Nuclear and Energy Research Institute (IPEN/CNEN), Av. Prof. Lineu Prestes, 2242 - Cidade Universitaria da USP - Butanta, Sao Paulo - SP - Brazil - CEP: 05508-000 (Brazil)

    2012-05-15

    The aim of the present work was to obtain stabilized high specific activity (HSA) {sup 111}In-labeled bombesin conjugates for preclinical evaluations. Parameters influencing the kinetics of labeling were investigated and the effect of stabilizers on HSA radiopeptides stability at room temperature were systematically categorized applying chromatography techniques. A SA of 174 GBq/{mu}mol was achieved with high radiochemical purity, but the labeled compounds exhibited low stability. The addition of stabilizers avoided their radiolysis and significantly increased their stability. - Highlights: Black-Right-Pointing-Pointer We aimed to obtain stabilized high specific activity (SA) {sup 111}In-labeled bombesin conjugates. Black-Right-Pointing-Pointer The effect of stabilizers on high SA radiopeptides stability were investigated. Black-Right-Pointing-Pointer A maximum specific activity of 174 GBq/{mu}mol was achieved. Black-Right-Pointing-Pointer The studied stabilizers significantly increased the stability of high SA radiopeptides. Black-Right-Pointing-Pointer These stabilized bombesin conjugates will be applied in preclinical studies.

  7. Numerical Computation of Detonation Stability

    KAUST Repository

    Kabanov, Dmitry

    2018-06-03

    Detonation is a supersonic mode of combustion that is modeled by a system of conservation laws of compressible fluid mechanics coupled with the equations describing thermodynamic and chemical properties of the fluid. Mathematically, these governing equations admit steady-state travelling-wave solutions consisting of a leading shock wave followed by a reaction zone. However, such solutions are often unstable to perturbations and rarely observed in laboratory experiments. The goal of this work is to study the stability of travelling-wave solutions of detonation models by the following novel approach. We linearize the governing equations about a base travelling-wave solution and solve the resultant linearized problem using high-order numerical methods. The results of these computations are postprocessed using dynamic mode decomposition to extract growth rates and frequencies of the perturbations and predict stability of travelling-wave solutions to infinitesimal perturbations. We apply this approach to two models based on the reactive Euler equations for perfect gases. For the first model with a one-step reaction mechanism, we find agreement of our results with the results of normal-mode analysis. For the second model with a two-step mechanism, we find that both types of admissible travelling-wave solutions exhibit the same stability spectra. Then we investigate the Fickett’s detonation analogue coupled with a particular reaction-rate expression. In addition to the linear stability analysis of this model, we demonstrate that it exhibits rich nonlinear dynamics with multiple bifurcations and chaotic behavior.

  8. Individuals with chronic ankle instability exhibit dynamic postural stability deficits and altered unilateral landing biomechanics: A systematic review.

    Science.gov (United States)

    Simpson, Jeffrey D; Stewart, Ethan M; Macias, David M; Chander, Harish; Knight, Adam C

    2018-06-13

    To evaluate the literature regarding unilateral landing biomechanics and dynamic postural stability in individuals with and without chronic ankle instability (CAI). Four online databases (PubMed, ScienceDirect, Scopus, and SportDiscus) were searched from the earliest records to 31 January 2018, as well as reference sections of related journal articles, to complete the systematic search. Studies investigating the influence of CAI on unilateral landing biomechanics and dynamic postural stability were systematically reviewed and evaluated. Twenty articles met the criteria and were included in the systematic review. Individuals with CAI were found to have deficits in dynamic postural stability on the affected limb with medium to large effect sizes and altered lower extremity kinematics, most notably in the ankle and knee, with medium to large effect sizes. Additionally, greater loading rates and peak ground reaction forces, in addition to reductions in ankle muscle activity were also found in individuals with CAI during unilateral jump-landing tasks. Individuals with CAI demonstrate dynamic postural stability deficits, lower extremity kinematic alterations, and reduced neuromuscular control during unilateral jump-landings. These are likely factors that contribute recurrent lateral ankle sprain injuries during dynamic activity in individuals with CAI. Copyright © 2018 Elsevier Ltd. All rights reserved.

  9. Enhanced stabilization of collagen by furfural.

    Science.gov (United States)

    Lakra, Rachita; Kiran, Manikantan Syamala; Usha, Ramamoorthy; Mohan, Ranganathan; Sundaresan, Raja; Korrapati, Purna Sai

    2014-04-01

    Furfural (2-furancarboxaldehyde), a product derived from plant pentosans, has been investigated for its interaction with collagen. Introduction of furfural during fibril formation enhanced the thermal and mechanical stability of collagen. Collagen films treated with furfural exhibited higher denaturation temperature (Td) (pFurfural and furfural treated collagen films did not have any cytotoxic effect. Rheological characterization showed an increase in shear stress and shear viscosity with increasing shear rate for treated collagen. Circular dichroism (CD) studies indicated that the furfural did not have any impact on triple helical structure of collagen. Scanning electron microscopy (SEM) of furfural treated collagen exhibited small sized porous structure in comparison with untreated collagen. Thus this study provides an alternate ecologically safe crosslinking agent for improving the stability of collagen for biomedical and industrial applications. Copyright © 2014 Elsevier B.V. All rights reserved.

  10. Inter-subject FDG PET Brain Networks Exhibit Multi-scale Community Structure with Different Normalization Techniques.

    Science.gov (United States)

    Sperry, Megan M; Kartha, Sonia; Granquist, Eric J; Winkelstein, Beth A

    2018-07-01

    Inter-subject networks are used to model correlations between brain regions and are particularly useful for metabolic imaging techniques, like 18F-2-deoxy-2-(18F)fluoro-D-glucose (FDG) positron emission tomography (PET). Since FDG PET typically produces a single image, correlations cannot be calculated over time. Little focus has been placed on the basic properties of inter-subject networks and if they are affected by group size and image normalization. FDG PET images were acquired from rats (n = 18), normalized by whole brain, visual cortex, or cerebellar FDG uptake, and used to construct correlation matrices. Group size effects on network stability were investigated by systematically adding rats and evaluating local network connectivity (node strength and clustering coefficient). Modularity and community structure were also evaluated in the differently normalized networks to assess meso-scale network relationships. Local network properties are stable regardless of normalization region for groups of at least 10. Whole brain-normalized networks are more modular than visual cortex- or cerebellum-normalized network (p network resolutions where modularity differs most between brain and randomized networks. Hierarchical analysis reveals consistent modules at different scales and clustering of spatially-proximate brain regions. Findings suggest inter-subject FDG PET networks are stable for reasonable group sizes and exhibit multi-scale modularity.

  11. Development of temporal and spatial bimanual coordination during childhood

    OpenAIRE

    de Boer, B.J.; Peper, C.E.; Beek, P.J.

    2012-01-01

    Developmental changes in bimanual coordination were examined in four age groups: 6/7, 10/11, 14/15 years, and young adults. Temporal coupling was assessed through the stabilizing contributions of interlimb interactions related to planning, error correction, and reflexes during rhythmic wrist movements, by comparing various unimanual and bimanual tasks involving passive and active movements. Spatial coupling was assessed via bimanual line-circle drawing. With increasing age, temporal stability...

  12. Exhibition

    CERN Document Server

    Staff Association

    2017-01-01

    A Look of Hope Islam Mahmoud Sweity From 19 to 30 June 2017 CERN Meyrin, Main Building Islam Mahmoud Sweity Islam Mahmoud Sweity was born in 1997 at Beit Awwa, Palestine. She is currently following a course to get an Art diploma of Painting at the college of Fine Arts at An-Najah National University under the supervision of Esmat Al As'aad. Her portraits, landscapes and still life paintings are full of life and shining colours. Charged of emotional empathy they catch the attention of the viewer and are reminding us that life is beautiful and worth living in spite of all difficulties we have to go through. She participated in many exhibitions and has exposed her drawings in 2015 at CERN and in France in the framework of the exhibition "The Origin“, and in 2017 in the Former Yugoslav Republic of Macedonia, Palestina and Jordan. In this exhibition the oil paintings made in the past year will be presented. For more information : staff.association@cern.ch | T&eacu...

  13. Spatial Variability of Soil Morphorlogical and Physico- Chemical ...

    African Journals Online (AJOL)

    user

    The available moisture of soil was very low thus water holding capacity (WHC) and wilting point (WP) of the soil was ... with spatial distribution of soil properties and its effect on ... Pore size and root .... nutrient and have better stability. Thus.

  14. Two-Dimensional Simulation of Spatial-Temporal Behaviors About Period Doubling Bifurcation in an Atmospheric-Pressure Dielectric Barrier Discharge

    International Nuclear Information System (INIS)

    Zhang Jiao; Wang Yanhui; Wang Dezhen; Zhuang Juan

    2014-01-01

    As a spatially extended dissipated system, atmospheric-pressure dielectric barrier discharges (DBDs) could in principle possess complex nonlinear behaviors. In order to improve the stability and uniformity of atmospheric-pressure dielectric barrier discharges, studies on temporal behaviors and radial structure of discharges with strong nonlinear behaviors under different controlling parameters are much desirable. In this paper, a two-dimensional fluid model is developed to simulate the radial discharge structure of period-doubling bifurcation, chaos, and inverse period-doubling bifurcation in an atmospheric-pressure DBD. The results show that the period-2n (n = 1, 2…) and chaotic discharges exhibit nonuniform discharge structure. In period-2n or chaos, not only the shape of current pulses doesn't remains exactly the same from one cycle to another, but also the radial structures, such as discharge spatial evolution process and the strongest breakdown region, are different in each neighboring discharge event. Current-voltage characteristics of the discharge system are studied for further understanding of the radial structure. (low temperature plasma)

  15. Exhibiting Epistemic Objects

    DEFF Research Database (Denmark)

    Tybjerg, Karin

    2017-01-01

    of exhibiting epistemic objects that utilize their knowledge-generating potential and allow them to continue to stimulate curiosity and generate knowledge in the exhibition. The epistemic potential of the objects can then be made to work together with the function of the exhibition as a knowledge-generating set...

  16. Modeling spatial processes with unknown extremal dependence class

    KAUST Repository

    Huser, Raphaë l G.; Wadsworth, Jennifer L.

    2017-01-01

    Many environmental processes exhibit weakening spatial dependence as events become more extreme. Well-known limiting models, such as max-stable or generalized Pareto processes, cannot capture this, which can lead to a preference for models

  17. On Information Metrics for Spatial Coding.

    Science.gov (United States)

    Souza, Bryan C; Pavão, Rodrigo; Belchior, Hindiael; Tort, Adriano B L

    2018-04-01

    The hippocampal formation is involved in navigation, and its neuronal activity exhibits a variety of spatial correlates (e.g., place cells, grid cells). The quantification of the information encoded by spikes has been standard procedure to identify which cells have spatial correlates. For place cells, most of the established metrics derive from Shannon's mutual information (Shannon, 1948), and convey information rate in bits/s or bits/spike (Skaggs et al., 1993, 1996). Despite their widespread use, the performance of these metrics in relation to the original mutual information metric has never been investigated. In this work, using simulated and real data, we find that the current information metrics correlate less with the accuracy of spatial decoding than the original mutual information metric. We also find that the top informative cells may differ among metrics, and show a surrogate-based normalization that yields comparable spatial information estimates. Since different information metrics may identify different neuronal populations, we discuss current and alternative definitions of spatially informative cells, which affect the metric choice. Copyright © 2018 IBRO. Published by Elsevier Ltd. All rights reserved.

  18. Reliability Analysis of Dynamic Stability in Waves

    DEFF Research Database (Denmark)

    Søborg, Anders Veldt

    2004-01-01

    exhibit sufficient characteristics with respect to slope at zero heel (GM value), maximum leverarm, positive range of stability and area below the leverarm curve. The rule-based requirements to calm water leverarm curves are entirely based on experience obtained from vessels in operation and recorded......The assessment of a ship's intact stability is traditionally based on a semi-empirical deterministic concept that evaluates the characteristics of ship's calm water restoring leverarm curves. Today the ship is considered safe with respect to dynamic stability if its calm water leverarm curves...... accidents in the past. The rules therefore only leaves little room for evaluation and improvement of safety of a ship's dynamic stability. A few studies have evaluated the probability of ship stability loss in waves using Monte Carlo simulations. However, since this probability may be in the order of 10...

  19. Spatial representations are specific to different domains of knowledge.

    Directory of Open Access Journals (Sweden)

    Rowena Beecham

    Full Text Available There is evidence that many abstract concepts are represented cognitively in a spatial format. However, it is unknown whether similar spatial processes are employed in different knowledge domains, or whether individuals exhibit similar spatial profiles within and across domains. This research investigated similarities in spatial representation in two knowledge domains--mathematics and music. Sixty-one adults completed analogous number magnitude and pitch discrimination tasks: the Spatial-Numerical Association of Response Codes and Spatial-Musical Association of Response Codes tasks. Subgroups of individuals with different response patterns were identified through cluster analyses. For both the mathematical and musical tasks, approximately half of the participants showed the expected spatial judgment effect when explicitly cued to focus on the spatial properties of the stimuli. Despite this, performances on the two tasks were largely independent. Consistent with previous research, the study provides evidence for the spatial representation of number and pitch in the majority of individuals. However, there was little evidence to support the claim that the same spatial representation processes underpin mathematical and musical judgments.

  20. Spatial pattern formation induced by Gaussian white noise.

    Science.gov (United States)

    Scarsoglio, Stefania; Laio, Francesco; D'Odorico, Paolo; Ridolfi, Luca

    2011-02-01

    The ability of Gaussian noise to induce ordered states in dynamical systems is here presented in an overview of the main stochastic mechanisms able to generate spatial patterns. These mechanisms involve: (i) a deterministic local dynamics term, accounting for the local rate of variation of the field variable, (ii) a noise component (additive or multiplicative) accounting for the unavoidable environmental disturbances, and (iii) a linear spatial coupling component, which provides spatial coherence and takes into account diffusion mechanisms. We investigate these dynamics using analytical tools, such as mean-field theory, linear stability analysis and structure function analysis, and use numerical simulations to confirm these analytical results. Copyright © 2010 Elsevier Inc. All rights reserved.

  1. Quantifying Landscape Spatial Pattern: What Is the State of the Art?

    Science.gov (United States)

    Eric J. Gustafson

    1998-01-01

    Landscape ecology is based on the premise that there are strong links between ecological pattern and ecological function and process. Ecological systems are spatially heterogeneous, exhibiting consid-erable complexity and variability in time and space. This variability is typically represented by categorical maps or by a collection of samples taken at specific spatial...

  2. Spatial distribution of aquatic insects

    DEFF Research Database (Denmark)

    Iversen, Lars Lønsmann

    (time since glacial disturbance and habitat stability) and question the generality of these processes for the understanding of species richness gradients in European rivers. Using regional distributions of European mayflies, stoneflies, and caddisflies this chapter demonstrates that differences...... and shape the habitat requirements and distribution of one of the most affected groups of freshwater species: aquatic insects. It comprises four chapters each addressing different spatial factors in relation to the occurrence of aquatic insects in Europe. Chapter I examine two spatial ecological processes...... niche is derived from local distribution patterns, without incorporating landscape history it can lead to an erroneous niche definition. Chapter III provides some of the first evidence for differences in dispersal phenology related to flight potential in aquatic insects. The chapter highlights...

  3. Validation of three-dimensional incompressible spatial direct numerical simulation code: A comparison with linear stability and parabolic stability equation theories for boundary-layer transition on a flat plate

    Science.gov (United States)

    Joslin, Ronald D.; Streett, Craig L.; Chang, Chau-Lyan

    1992-01-01

    Spatially evolving instabilities in a boundary layer on a flat plate are computed by direct numerical simulation (DNS) of the incompressible Navier-Stokes equations. In a truncated physical domain, a nonstaggered mesh is used for the grid. A Chebyshev-collocation method is used normal to the wall; finite difference and compact difference methods are used in the streamwise direction; and a Fourier series is used in the spanwise direction. For time stepping, implicit Crank-Nicolson and explicit Runge-Kutta schemes are used to the time-splitting method. The influence-matrix technique is used to solve the pressure equation. At the outflow boundary, the buffer-domain technique is used to prevent convective wave reflection or upstream propagation of information from the boundary. Results of the DNS are compared with those from both linear stability theory (LST) and parabolized stability equation (PSE) theory. Computed disturbance amplitudes and phases are in very good agreement with those of LST (for small inflow disturbance amplitudes). A measure of the sensitivity of the inflow condition is demonstrated with both LST and PSE theory used to approximate inflows. Although the DNS numerics are very different than those of PSE theory, the results are in good agreement. A small discrepancy in the results that does occur is likely a result of the variation in PSE boundary condition treatment in the far field. Finally, a small-amplitude wave triad is forced at the inflow, and simulation results are compared with those of LST. Again, very good agreement is found between DNS and LST results for the 3-D simulations, the implication being that the disturbance amplitudes are sufficiently small that nonlinear interactions are negligible.

  4. Council Chamber exhibition

    CERN Multimedia

    CERN Bulletin

    2010-01-01

    To complete the revamp of CERN’s Council Chamber, a new exhibition is being installed just in time for the June Council meetings.   Panels will showcase highlights of CERN’s history, using some of the content prepared for the exhibitions marking 50 years of the PS, which were displayed in the main building last November. The previous photo exhibition in the Council Chamber stopped at the 1970s. To avoid the new panels becoming quickly out of date, photos are grouped together around specific infrastructures, rather than following a classic time-line. “We have put the focus on the accelerators – the world-class facilities that CERN has been offering researchers over the years, from the well-known large colliders to the lesser-known smaller facilities,” says Emma Sanders, who worked on the content. The new exhibition will be featured in a future issue of the Bulletin with photos and an interview with Fabienne Marcastel, designer of the exhibit...

  5. Linear stability analysis of supersonic axisymmetric jets

    Directory of Open Access Journals (Sweden)

    Zhenhua Wan

    2014-01-01

    Full Text Available Stabilities of supersonic jets are examined with different velocities, momentum thicknesses, and core temperatures. Amplification rates of instability waves at inlet are evaluated by linear stability theory (LST. It is found that increased velocity and core temperature would increase amplification rates substantially and such influence varies for different azimuthal wavenumbers. The most unstable modes in thin momentum thickness cases usually have higher frequencies and azimuthal wavenumbers. Mode switching is observed for low azimuthal wavenumbers, but it appears merely in high velocity cases. In addition, the results provided by linear parabolized stability equations show that the mean-flow divergence affects the spatial evolution of instability waves greatly. The most amplified instability waves globally are sometimes found to be different from that given by LST.

  6. MHD stability studies in the Proto S-1 A/B device

    International Nuclear Information System (INIS)

    Munson, C.; Janos, A.; Newhouse, M.; Salberta, E.; Wysocki, F.; Yamada, M.

    1982-01-01

    An experimental study of the gross MHD stability properties of Spheromak plasmas in the Proto S-1 A/B device is presented. Utilizing the previously demonstrated S-1 slow formation technique, plasmas have been produced which exhibit the predicted tilting instability in a regime of slightly negative field index. A relatively simple passive coil system suggested by numerical stability studies has proven to be effective in stabilizing the observed tilting mode

  7. Measuring the influence of Canadian carbon stabilization programs on natural gas exports to the United States via a 'bottom-up' intertemporal spatial price equilibrium model

    International Nuclear Information System (INIS)

    Gabriel, S.A.; Vikas, S.; Ribar, D.M.

    2000-01-01

    In this paper, we present the results of a study of the impact of Canadian carbon stabilization programs on exports of natural gas to the United States. This work was based on a study conducted for the US Environmental Protection Agency. The Gas Systems Analysis model (GSAM), developed by ICF Consulting for the US Department of Energy, was used to gauge the overall impact of the stabilization programs on the North American natural gas market. GSAM is an intertemporal, spatial price equilibrium (SPE) type model of the North American natural gas system. Salient features of this model include characterization of over 17 000 gas production reservoirs with explicit reservoir-level geologic and economic information used to build up the supply side of the market. On the demand side, four sectors, residential, commercial, industrial and electric power generation, are characterized in the model. Lastly, both above and below ground storage facilities as well as a comprehensive pipeline network are used with the supply and demand side characterizations to arrive at estimates of market equilibrium prices and quantities and flows. 35 refs

  8. Dynamical stability for finite quantum spin chains against a time-periodic inhomogeneous perturbation

    International Nuclear Information System (INIS)

    Kudo, Kazue; Nakamura, Katsuhiro

    2009-01-01

    We investigate dynamical stability of the ground state against a time-periodic and spatially-inhomogeneous magnetic field for finite quantum XXZ spin chains. We use the survival probability as a measure of stability and demonstrate that it decays as P(t) ∝ t -1/2 under a certain condition. The dynamical properties should also be related to the level statistics of the XXZ spin chains with a constant spatially-inhomogeneous magnetic field. The level statistics depends on the anisotropy parameter and the field strength. We show how the survival probability depends on the anisotropy parameter, the strength and frequency of the field.

  9. EXHIBITION: Accelerated Particles

    CERN Multimedia

    2004-01-01

    An exhibition of plastic arts and two evenings of performances by sound and visual artists as part of CERN's 50th anniversary celebrations. Fifty candles for CERN, an international laboratory renowned for fundamental research, is a cause for celebration. Since March this year, Geneva and neighbouring parts of France have been the venues for a wealth of small and large-scale events, which will continue until November. Given CERN's location in the commune of Meyrin, the ForuMeyrin is hosting exhibitions of plastic arts and performances entitled: Accelerated Particles. Several works will be exhibited and performed in two 'salons'. Salon des matières: An exhibition of plastic arts From Tues 12 October to Wed 3 November 2004 Tuesdays to Fridays: 16:00 to 19:00 Saturdays: 14:00 to 18:00 Exhibition open late on performance nights, entrance free Salon des particules: Musical and visual performances Tues 12 and Mon 25 October from 20:00 to 23:00 Preview evening for both events: Tues 12 October from 18:...

  10. Assessment of stability during gait in patients with spinal deformity-A preliminary analysis using the dynamic stability margin.

    Science.gov (United States)

    Simon, Anne-Laure; Lugade, Vipul; Bernhardt, Kathie; Larson, A Noelle; Kaufman, Kenton

    2017-06-01

    Daily living activities are dynamic, requiring spinal motion through space. Current assessment of spinal deformities is based on static measurements from full-spine standing radiographs. Tools to assess dynamic stability during gait might be useful to enhance the standard evaluation. The aim of this study was to evaluate gait dynamic imbalance in patients with spinal deformity using the dynamic stability margin (DSM). Twelve normal subjects and 17 patients with spinal deformity were prospectively recruited. A kinematic 3D gait analysis was performed for the control group (CG) and the spinal deformity group (SDG). The DSM (distance between the extrapolated center of mass and the base of support) and time-distance parameters were calculated for the right and left side during gait. The relationship between DSM and step length was assessed using three variables: gait stability, symmetry, and consistency. Variables' accuracy was validated by a discriminant analysis. Patients with spinal deformity exhibited gait instability according to the DSM (0.25m versus 0.31m) with decreased velocity (1.1ms -1 versus 1.3ms -1 ) and decreased step length (0.32m versus 0.38m). According to the discriminant analysis, gait stability was the more accurate variable (area under the curve AUC=0.98) followed by gait symmetry and consistency. However, gait consistency showed 100% of specificity, sensitivity, and accuracy of precision. The DSM showed that patients with spinal malalignment exhibit decreased gait stability, symmetry, and consistency besides gait time-distance parameter changes. Additional work is required to determine how to apply the DSM for preoperative and postoperative spinal deformity management. Copyright © 2017. Published by Elsevier B.V.

  11. Spatial learning depends on both the addition and removal of new hippocampal neurons.

    Directory of Open Access Journals (Sweden)

    David Dupret

    2007-08-01

    Full Text Available The role of adult hippocampal neurogenesis in spatial learning remains a matter of debate. Here, we show that spatial learning modifies neurogenesis by inducing a cascade of events that resembles the selective stabilization process characterizing development. Learning promotes survival of relatively mature neurons, apoptosis of more immature cells, and finally, proliferation of neural precursors. These are three interrelated events mediating learning. Thus, blocking apoptosis impairs memory and inhibits learning-induced cell survival and cell proliferation. In conclusion, during learning, similar to the selective stabilization process, neuronal networks are sculpted by a tightly regulated selection and suppression of different populations of newly born neurons.

  12. Stability of Spatial Distributions of Stink Bugs, Boll Injury, and NDVI in Cotton.

    Science.gov (United States)

    Reay-Jones, Francis P F; Greene, Jeremy K; Bauer, Philip J

    2016-10-01

    A 3-yr study was conducted to determine the degree of aggregation of stink bugs and boll injury in cotton, Gossypium hirsutum L., and their spatial association with a multispectral vegetation index (normalized difference vegetation index [NDVI]). Using the spatial analysis by distance indices analyses, stink bugs were less frequently aggregated (17% for adults and 4% for nymphs) than boll injury (36%). NDVI values were also significantly aggregated within fields in 19 of 48 analyses (40%), with the majority of significant indices occurring in July and August. Paired NDVI datasets from different sampling dates were frequently associated (86.5% for weekly intervals among datasets). Spatial distributions of both stink bugs and boll injury were less stable than for NDVI, with positive associations varying from 12.5 to 25% for adult stink bugs for weekly intervals, depending on species. Spatial distributions of boll injury from stink bug feeding were more stable than stink bugs, with 46% positive associations among paired datasets with weekly intervals. NDVI values were positively associated with boll injury from stink bug feeding in 11 out of 22 analyses, with no significant negative associations. This indicates that NDVI has potential as a component of site-specific management. Future work should continue to examine the value of remote sensing for insect management in cotton, with an aim to develop tools such as risk assessment maps that will help growers to reduce insecticide inputs. © The Authors 2016. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  13. Strongly nonlinear theory of rapid solidification near absolute stability

    Science.gov (United States)

    Kowal, Katarzyna N.; Altieri, Anthony L.; Davis, Stephen H.

    2017-10-01

    morphological number, as well as the amplitude. The critical amplitude, at which solutions loose periodicity, depends on a single combination of parameters independent of the morphological number that indicate that non-periodic growth is most commonly present for moderate disequilibrium parameters. The spatial distribution of the interface develops deepening roots at late times. Similar spatial distributions are also seen in the limit in which both the cellular and oscillatory modes are close to absolute stability, and the roots deepen with larger departures from the two absolute stability boundaries.

  14. Interactive spatial multimedia for communication of art in the physical museum space

    DEFF Research Database (Denmark)

    Kortbek, Karen Johanne; Grønbæk, Kaj

    2008-01-01

    of the artworks we apply three spatial multimedia techniques where the only interaction device needed is the human body. The three techniques are: 1) spatially bounded audio; 2) floor-based multimedia; 3) multimedia interior. The paper describes the application of these techniques for communication of information...... without disturbing the art works. This has usually been limited to individual audio guides. In our case we strive to achieve holistic and social experiences with seamless transitions between art experience and communication related to the artworks. To reach a holistic experience with minimal disturbance...... in a Mariko Mori exhibition. The multimedia installations and their implementation are described. It is argued that the utilization of the spatial multimedia techniques support holistic and social art experience. The multimedia installations were in function for a three and a half month exhibition period...

  15. Assessment of tuberculosis spatial hotspot areas in Antananarivo, Madagascar, by combining spatial analysis and genotyping.

    Science.gov (United States)

    Ratovonirina, Noël Harijaona; Rakotosamimanana, Niaina; Razafimahatratra, Solohery Lalaina; Raherison, Mamy Serge; Refrégier, Guislaine; Sola, Christophe; Rakotomanana, Fanjasoa; Rasolofo Razanamparany, Voahangy

    2017-08-14

    Tuberculosis (TB) remains a public health problem in Madagascar. A crucial element of TB control is the development of an easy and rapid method for the orientation of TB control strategies in the country. Our main objective was to develop a TB spatial hotspot identification method by combining spatial analysis and TB genotyping method in Antananarivo. Sputa of new pulmonary TB cases from 20 TB diagnosis and treatment centers (DTCs) in Antananarivo were collected from August 2013 to May 2014 for culture. Mycobacterium tuberculosis complex (MTBC) clinical isolates were typed by spoligotyping on a Luminex® 200 platform. All TB patients were respectively localized according to their neighborhood residence and the spatial distribution of all pulmonary TB patients and patients with genotypic clustered isolates were scanned respectively by the Kulldorff spatial scanning method for identification of significant spatial clustering. Areas exhibiting spatial clustering of patients with genotypic clustered isolates were considered as hotspot TB areas for transmission. Overall, 467 new cases were included in the study, and 394 spoligotypes were obtained (84.4%). New TB cases were distributed in 133 of the 192 Fokontany (administrative neighborhoods) of Antananarivo (1 to 15 clinical patients per Fokontany) and patients with genotypic clustered isolates were distributed in 127 of the 192 Fokontany (1 to 13 per Fokontany). A single spatial focal point of epidemics was detected when ignoring genotypic data (p = 0.039). One Fokontany of this focal point and three additional ones were detected to be spatially clustered when taking genotypes into account (p Madagascar and will allow better TB control strategies by public health authorities.

  16. Postural stability changes in the elderly with cataract simulation and refractive blur.

    Science.gov (United States)

    Anand, Vijay; Buckley, John G; Scally, Andy; Elliott, David B

    2003-11-01

    To determine the influence of cataractous and refractive blur on postural stability and limb-load asymmetry (LLA) and to establish how postural stability changes with the spatial frequency and contrast of the visual stimulus. Thirteen elderly subjects (mean age, 70.76 +/- 4.14 [SD] years) with no history of falls and normal vision were recruited. Postural stability was determined as the root mean square [RMS] of the center of pressure (COP) signal in the anterior-posterior (A-P) and medial-lateral directions and LLA was determined as the ratio of the average body weight placed on the more-loaded limb to the less-loaded limb, recorded during a 30-second period. Data were collected under normal standing conditions and with somatosensory system input disrupted. Measurements were repeated with four visual targets with high (8 cyc/deg) or low (2 cyc/deg) spatial frequency and high (Weber contrast, approximately 95%) or low (Weber contrast, approximately 25%) contrast. Postural stability was measured under conditions of binocular refractive blur of 0, 1, 2, 4, and 8 D and with cataract simulation. The data were analyzed in a population-averaged linear model. The cataract simulation caused significant increases in postural instability equivalent to that caused by 8-D blur conditions, and its effect was greater when the input from the somatosensory system was disrupted. High spatial frequency targets increased postural instability. Refractive blur, cataract simulation, or eye closure had no effect on LLA. Findings indicate that cataractous and refractive blur increase postural instability, and show why the elderly, many of whom have poor vision along with musculoskeletal and central nervous system degeneration, are at greater risk of falling. Findings also highlight that changes in contrast sensitivity rather than resolution changes are responsible for increasing postural instability. Providing low spatial frequency information in certain environments may be useful in

  17. Britain exhibition at CERN

    CERN Multimedia

    Bertin; CERN PhotoLab

    1969-01-01

    The United Kingdom inaugurated the Industrial Exhibitions in 1968, and it wasn't till 1971 that other countries staged exhibitions at CERN. This photo was taken in 1969, at the second British exhibition, where 16 companies were present.

  18. Gender difference of ankle stability in the sagittal and frontal planes.

    Science.gov (United States)

    Hanzlick, Harrison; Hyunglae Lee

    2017-07-01

    This paper offers quantification of ankle stability in relation to simulated haptic environments of varying stiffness. This study analyzes the stability trends of male and female subjects independently over a wide range of simulated environments after subjects were exposed to vigorous position perturbation. Ankle stability was quantified for both degrees-of-freedom of the ankle in the sagittal and frontal planes. Subjects' stability consistently decreased when exposed to environments of negative simulated stiffness. In the frontal plane, male and female subjects exhibited nearly identical stability levels. In the sagittal plane, however, male subjects demonstrated marginally more stability than female subjects in environments with negative stiffness. Results of this study are beneficial to understanding situations in which the ankle is likely to lose stability, potentially resulting in injury.

  19. Passivation and Stabilization of Aluminum Nanoparticles for Energetic Materials

    Directory of Open Access Journals (Sweden)

    Matthew Flannery

    2015-01-01

    Full Text Available In aircraft applications, fuel is used not only as a propellant but also as a coolant and improving both the thermal conductivity and combustion enthalpy of the fuel is beneficial in these applications. These properties can be enhanced by dispersing aluminum nanoparticles into the fuel; however, the nanoparticles require stabilization from agglomeration and passivation from oxidation in order for these benefits to be realized in aircraft applications. To provide this passivation and stabilization, aluminum nanoparticles were encapsulated with a coating by the plasma enhanced chemical vapor deposition (PE-CVD method from toluene precursors. The thermal conductivity, combustion and ignition properties, and stability of the nanoparticles dispersed in RP-2 fuel were subsequently evaluated. In addition, the effect of dispersing aluminum nanoparticles in RP-2 fuel on the erosion rate of fuel nozzles was evaluated. The dispersion of PE-CVD coated aluminum nanoparticles at a concentration of 3.0% by volume exhibited a 17.7% and 0.9% increase in thermal conductivity and volumetric enthalpy of combustion, respectively, compared to the baseline RP-2 fuel. Additionally, particle size analysis (PSA of the PE-CVD coated aluminum nanofuel exhibited retention of particle size over a five-month storage period and erosion testing of a 1 mm stainless steel nozzle exhibited a negligible 1% change in discharge coefficient after 100 hours of testing.

  20. Modulation equations for spatially periodic systems: derivation and solutions

    NARCIS (Netherlands)

    Schielen, R.; Doelman, A.

    1996-01-01

    We study a class of partial dierential equations in one spatial dimension, which can be seen as model equations for the analysis of pattern formation in physical systems dened on unbounded, weakly oscillating domains. We perform a linear and weakly nonlinear stability analysis for solutions that

  1. Parabolized stability equations

    Science.gov (United States)

    Herbert, Thorwald

    1994-01-01

    The parabolized stability equations (PSE) are a new approach to analyze the streamwise evolution of single or interacting Fourier modes in weakly nonparallel flows such as boundary layers. The concept rests on the decomposition of every mode into a slowly varying amplitude function and a wave function with slowly varying wave number. The neglect of the small second derivatives of the slowly varying functions with respect to the streamwise variable leads to an initial boundary-value problem that can be solved by numerical marching procedures. The PSE approach is valid in convectively unstable flows. The equations for a single mode are closely related to those of the traditional eigenvalue problems for linear stability analysis. However, the PSE approach does not exploit the homogeneity of the problem and, therefore, can be utilized to analyze forced modes and the nonlinear growth and interaction of an initial disturbance field. In contrast to the traditional patching of local solutions, the PSE provide the spatial evolution of modes with proper account for their history. The PSE approach allows studies of secondary instabilities without the constraints of the Floquet analysis and reproduces the established experimental, theoretical, and computational benchmark results on transition up to the breakdown stage. The method matches or exceeds the demonstrated capabilities of current spatial Navier-Stokes solvers at a small fraction of their computational cost. Recent applications include studies on localized or distributed receptivity and prediction of transition in model environments for realistic engineering problems. This report describes the basis, intricacies, and some applications of the PSE methodology.

  2. Digital collections and exhibits

    CERN Document Server

    Denzer, Juan

    2015-01-01

    Today's libraries are taking advantage of cutting-edge technologies such as flat panel displays using touch, sound, and hands-free motions to design amazing exhibits using everything from simple computer hardware to advanced technologies such as the Microsoft Kinect. Libraries of all types are striving to add new interactive experiences for their patrons through exciting digital exhibits, both online and off. Digital Collections and Exhibits takes away the mystery of designing stunning digital exhibits to spotlight library trea

  3. Early Warning Signals of Ecological Transitions: Methods for Spatial Patterns

    Science.gov (United States)

    Brock, William A.; Carpenter, Stephen R.; Ellison, Aaron M.; Livina, Valerie N.; Seekell, David A.; Scheffer, Marten; van Nes, Egbert H.; Dakos, Vasilis

    2014-01-01

    A number of ecosystems can exhibit abrupt shifts between alternative stable states. Because of their important ecological and economic consequences, recent research has focused on devising early warning signals for anticipating such abrupt ecological transitions. In particular, theoretical studies show that changes in spatial characteristics of the system could provide early warnings of approaching transitions. However, the empirical validation of these indicators lag behind their theoretical developments. Here, we summarize a range of currently available spatial early warning signals, suggest potential null models to interpret their trends, and apply them to three simulated spatial data sets of systems undergoing an abrupt transition. In addition to providing a step-by-step methodology for applying these signals to spatial data sets, we propose a statistical toolbox that may be used to help detect approaching transitions in a wide range of spatial data. We hope that our methodology together with the computer codes will stimulate the application and testing of spatial early warning signals on real spatial data. PMID:24658137

  4. Experimental study of coherence vortices: Local properties of phase singularities in a spatial coherence function

    DEFF Research Database (Denmark)

    Wang, W.; Duan, Z.H.; Hanson, Steen Grüner

    2006-01-01

    By controlling the irradiance of an extended quasimonochromatic, spatially incoherent source, an optical field is generated that exhibits spatial coherence with phase singularities, called coherence vortices. A simple optical geometry for direct visualization of coherence vortices is proposed, an...

  5. Fluorinated Phosphorene: Electrochemical Synthesis, Atomistic Fluorination, and Enhanced Stability.

    Science.gov (United States)

    Tang, Xian; Liang, Weiyuan; Zhao, Jinlai; Li, Zhongjun; Qiu, Meng; Fan, Taojian; Luo, Crystal Shaojuan; Zhou, Ye; Li, Yu; Guo, Zhinan; Fan, Dianyuan; Zhang, Han

    2017-12-01

    Phosphorene has attracted great interest due to its unique electronic and optoelectronic properties owing to its tunable direct and moderate band-gap in association with high carrier mobility. However, its intrinsic instability in air seriously hinders its practical applications, and problems of technical complexity and in-process degradation exist in currently proposed stabilization strategies. A facile pathway in obtaining and stabilizing phosphorene through a one-step, ionic liquid-assisted electrochemical exfoliation and synchronous fluorination process is reported in this study. This strategy enables fluorinated phosphorene (FP) to be discovered and large-scale, highly selective few-layer FP (3-6 atomic layers) to be obtained. The synthesized FP is found to exhibit unique morphological and optical characteristics. Possible atomistic fluorination configurations of FP are revealed by core-level binding energy shift calculations in combination with spectroscopic measurements, and the results indicate that electrolyte concentration significantly modulates the fluorination configurations. Furthermore, FP is found to exhibit enhanced air stability thanks to the antioxidation and antihydration effects of the introduced fluorine adatoms, and demonstrate excellent photothermal stability during a week of air exposure. These findings pave the way toward real applications of phosphorene-based nanophotonics. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  6. Evaluation Of Spatial Filters For Background Suppression In Infrared Mosaic Sensor Systems

    Science.gov (United States)

    Bergen, T. L.; Mazaika, P. K.

    1982-12-01

    Spaceborne infrared mosaic sensors have been proposed for future surveillance systems. Because these systems will generate a large volume of data, background suppression will require algorithms which use innovative architectures and minimal storage. This paper analyzes the implementation and performance of candidate temporal and spatial filters. Spatial filters are attractive because they require far less memory, can effectively exploit a parallel, pipelined architecture, and are relatively insensitive to target speed. However, the performance of spatial filtering is substantially worse than that of temporal filtering when the sensor has good line-of-sight stability.

  7. Long term stability of nanowire nanoelectronics in physiological environments.

    Science.gov (United States)

    Zhou, Wei; Dai, Xiaochuan; Fu, Tian-Ming; Xie, Chong; Liu, Jia; Lieber, Charles M

    2014-03-12

    Nanowire nanoelectronic devices have been exploited as highly sensitive subcellular resolution detectors for recording extracellular and intracellular signals from cells, as well as from natural and engineered/cyborg tissues, and in this capacity open many opportunities for fundamental biological research and biomedical applications. Here we demonstrate the capability to take full advantage of the attractive capabilities of nanowire nanoelectronic devices for long term physiological studies by passivating the nanowire elements with ultrathin metal oxide shells. Studies of Si and Si/aluminum oxide (Al2O3) core/shell nanowires in physiological solutions at 37 °C demonstrate long-term stability extending for at least 100 days in samples coated with 10 nm thick Al2O3 shells. In addition, investigations of nanowires configured as field-effect transistors (FETs) demonstrate that the Si/Al2O3 core/shell nanowire FETs exhibit good device performance for at least 4 months in physiological model solutions at 37 °C. The generality of this approach was also tested with in studies of Ge/Si and InAs nanowires, where Ge/Si/Al2O3 and InAs/Al2O3 core/shell materials exhibited stability for at least 100 days in physiological model solutions at 37 °C. In addition, investigations of hafnium oxide-Al2O3 nanolaminated shells indicate the potential to extend nanowire stability well beyond 1 year time scale in vivo. These studies demonstrate that straightforward core/shell nanowire nanoelectronic devices can exhibit the long term stability needed for a range of chronic in vivo studies in animals as well as powerful biomedical implants that could improve monitoring and treatment of disease.

  8. Modified silver nanowire transparent electrodes with exceptional stability against oxidation

    International Nuclear Information System (INIS)

    Idier, J; Neri, W; Ly, I; Poulin, P; Backov, R; Labrugère, C

    2016-01-01

    We report an easy method to prepare thin, flexible and transparent electrodes that show enhanced inertness toward oxidation using modified silver nanowires (Ag NWs). Stabilization is achieved through the adsorption of triphenylphosphine (PPh 3 ) onto the Ag NW hybrid dispersions prior to their 2D organization as transparent electrodes on polyethylene terephtalate (PET) films. After 110 days in air (20 °C) under atmospheric conditions, the transmittance of the PET/Ag NW/PPh 3 based films is nearly unchanged, while the transmittance of the PET/Ag NW-based films decreases by about 5%. The sheet resistance increases for both materials as time elapses, but the rate of increase is more than four times slower for films stabilized by PPh 3 . The improved transmittance and conductivity results in a significantly enhanced stability for the figure of merit σ dc /σ op . This phenomenon is highlighted in highly oxidative nitric acid vapor. The tested stabilized films in such conditions exhibit a decrease to σ dc /σ op of only 38% after 75 min, whereas conventional materials exhibit a relative loss of 71%. In addition, by contrast to other classes of stabilizers, such as polymer or graphene-based encapsulants, PPh 3 does not alter the transparency or conductivity of the modified films. While the present films are made by membrane filtration, the stabilization method could be implemented directly in other liquid processes, including industrially scalable ones. (paper)

  9. New quantitative approaches reveal the spatial preference of nuclear compartments in mammalian fibroblasts.

    Science.gov (United States)

    Weston, David J; Russell, Richard A; Batty, Elizabeth; Jensen, Kirsten; Stephens, David A; Adams, Niall M; Freemont, Paul S

    2015-03-06

    The nuclei of higher eukaryotic cells display compartmentalization and certain nuclear compartments have been shown to follow a degree of spatial organization. To date, the study of nuclear organization has often involved simple quantitative procedures that struggle with both the irregularity of the nuclear boundary and the problem of handling replicate images. Such studies typically focus on inter-object distance, rather than spatial location within the nucleus. The concern of this paper is the spatial preference of nuclear compartments, for which we have developed statistical tools to quantitatively study and explore nuclear organization. These tools combine replicate images to generate 'aggregate maps' which represent the spatial preferences of nuclear compartments. We present two examples of different compartments in mammalian fibroblasts (WI-38 and MRC-5) that demonstrate new knowledge of spatial preference within the cell nucleus. Specifically, the spatial preference of RNA polymerase II is preserved across normal and immortalized cells, whereas PML nuclear bodies exhibit a change in spatial preference from avoiding the centre in normal cells to exhibiting a preference for the centre in immortalized cells. In addition, we show that SC35 splicing speckles are excluded from the nuclear boundary and localize throughout the nucleoplasm and in the interchromatin space in non-transformed WI-38 cells. This new methodology is thus able to reveal the effect of large-scale perturbation on spatial architecture and preferences that would not be obvious from single cell imaging.

  10. The Stability of DSM Personality Disorders over Twelve to Eighteen Years

    Science.gov (United States)

    Nestadt, Gerald; Di, Chongzhi; Samuels, J F; Bienvenu, O J; Reti, I M; Costa, P; Eaton, William W; Bandeen-Roche, Karen

    2009-01-01

    Background Stability of personality disorders is assumed in most nomenclatures; however, the evidence for this is limited and inconsistent. The aim of this study is to investigate the stability of DSM-III personality disorders in a community sample of eastern Baltimore residents unselected for treatment. Methods Two hundred ninety four participants were examined on two occasions by psychiatrists using the same standardized examination twelve to eighteen years apart. All the DSM-III criteria for personality disorders were assessed. Item-response analysis was adapted into two approaches to assess the agreement between the personality measures on the two occasions. The first approach estimated stability in the underlying disorder, correcting for error in trait measurement, and the second approach estimated stability in the measured disorder, without correcting for item unreliability. Results Five of the ten personality disorders exhibited moderate stability in individuals: antisocial, avoidant, borderline, histrionic, and schizotypal. Associated estimated ICCs for stability of underlying disorder over time ranged between approximately 0.4 and 0.7–0.8. A sixth disorder, OCPD, exhibited appreciable stability with estimated ICC of approximately 0.2–0.3. Dependent, narcissistic, paranoid, and schizoid disorders were not demonstrably stable. Conclusions The findings suggest that six of the DSM personality disorder constructs themselves are stable, but that specific traits within the DSM categories are both of lesser importance than the constructs themselves and require additional specification. PMID:19656527

  11. Influence of a mobile robot on the spatial behaviour of quail chicks

    Energy Technology Data Exchange (ETDEWEB)

    De Margerie, E; Lumineau, S; Houdelier, C; Richard Yris, M-A, E-mail: emmanuel.demargerie@univ-rennes1.fr [CNRS UMR 6552 Ethologie Animale et Humaine, Universite Rennes 1, Rennes (France)

    2011-09-15

    Quail chicks encountered an autonomous mobile robot during their early development. The robot incorporated a heat source that stimulated following of chicks. The spatial behaviour of grown-up chicks was tested in an exploration test and a detour test. Chicks that grew with the mobile robot exhibited better spatial abilities than chicks grown with a static heat source. We discuss these results in the perspective of animal-robot interaction and of the role of early spatial experience on the behavioural development. (communication)

  12. Influence of a mobile robot on the spatial behaviour of quail chicks

    International Nuclear Information System (INIS)

    De Margerie, E; Lumineau, S; Houdelier, C; Richard Yris, M-A

    2011-01-01

    Quail chicks encountered an autonomous mobile robot during their early development. The robot incorporated a heat source that stimulated following of chicks. The spatial behaviour of grown-up chicks was tested in an exploration test and a detour test. Chicks that grew with the mobile robot exhibited better spatial abilities than chicks grown with a static heat source. We discuss these results in the perspective of animal-robot interaction and of the role of early spatial experience on the behavioural development. (communication)

  13. Finding a Place To Stand: Negotiating the Spatial Configuration of the Networked Computer Classroom.

    Science.gov (United States)

    Kent-Drury, Roxanne

    1998-01-01

    Theorizes the spatial dynamics of both traditional and Internet-networked classrooms to reveal that both exhibit indeterminate spatial characteristics, but that network connectivity renders this indeterminacy visible. Argues that networked classrooms need not be disorienting, if students recreate a center by designing a class Web site, creating…

  14. Spatially indirect excitons in coupled quantum wells

    Energy Technology Data Exchange (ETDEWEB)

    Lai, Chih-Wei Eddy [Univ. of California, Berkeley, CA (United States)

    2004-03-01

    Microscopic quantum phenomena such as interference or phase coherence between different quantum states are rarely manifest in macroscopic systems due to a lack of significant correlation between different states. An exciton system is one candidate for observation of possible quantum collective effects. In the dilute limit, excitons in semiconductors behave as bosons and are expected to undergo Bose-Einstein condensation (BEC) at a temperature several orders of magnitude higher than for atomic BEC because of their light mass. Furthermore, well-developed modern semiconductor technologies offer flexible manipulations of an exciton system. Realization of BEC in solid-state systems can thus provide new opportunities for macroscopic quantum coherence research. In semiconductor coupled quantum wells (CQW) under across-well static electric field, excitons exist as separately confined electron-hole pairs. These spatially indirect excitons exhibit a radiative recombination time much longer than their thermal relaxation time a unique feature in direct band gap semiconductor based structures. Their mutual repulsive dipole interaction further stabilizes the exciton system at low temperature and screens in-plane disorder more effectively. All these features make indirect excitons in CQW a promising system to search for quantum collective effects. Properties of indirect excitons in CQW have been analyzed and investigated extensively. The experimental results based on time-integrated or time-resolved spatially-resolved photoluminescence (PL) spectroscopy and imaging are reported in two categories. (i) Generic indirect exciton systems: general properties of indirect excitons such as the dependence of exciton energy and lifetime on electric fields and densities were examined. (ii) Quasi-two-dimensional confined exciton systems: highly statistically degenerate exciton systems containing more than tens of thousands of excitons within areas as small as (10 micrometer)2 were

  15. Cost-effective alternative to nano-encapsulation: Amorphous curcumin-chitosan nanoparticle complex exhibiting high payload and supersaturation generation.

    Science.gov (United States)

    Nguyen, Minh Hiep; Yu, Hong; Kiew, Tie Yi; Hadinoto, Kunn

    2015-10-01

    While the wide-ranging therapeutic activities of curcumin have been well established, its successful delivery to realize its true therapeutic potentials faces a major challenge due to its low oral bioavailability. Even though nano-encapsulation has been widely demonstrated to be effective in enhancing the bioavailability of curcumin, it is not without drawbacks (i.e. low payload and costly preparation). Herein we present a cost-effective bioavailability enhancement strategy of curcumin in the form of amorphous curcumin-chitosan nanoparticle complex (or curcumin nanoplex in short) exhibiting a high payload (>80%). The curcumin nanoplex was prepared by a simple yet highly efficient drug-polysaccharide complexation method that required only mixing of the curcumin and chitosan solutions under ambient condition. The effects of (1) pH and (2) charge ratio of chitosan to curcumin on the (i) physical characteristics of the nanoplex (i.e. size, colloidal stability and payload), (ii) complexation efficiency, and (iii) production yield were investigated from which the optimal preparation condition was determined. The nanoplex formation was found to favor low acidic pH and charge ratio below unity. At the optimal condition (i.e. pH 4.4. and charge ratio=0.8), stable curcumin nanoplex (≈260nm) was prepared at >90% complexation efficiency and ≈50% production yield. The amorphous state stability, colloidal stability, and in vitro non-cytotoxicity of the nanoplex were successfully established. The curcumin nanoplex produced prolonged supersaturation (3h) in the presence of hydroxypropyl methylcellulose (HPMC) at five times of the saturation solubility of curcumin. In addition, curcumin released from the nanoplex exhibited improved chemical stability owed to the presence of chitosan. Both results (i.e. high supersaturation and improved chemical stability) bode well for the ability of the curcumin nanoplex to enhance the bioavailability of curcumin clinically. Copyright © 2015

  16. Stability of glassy hierarchical networks

    Science.gov (United States)

    Zamani, M.; Camargo-Forero, L.; Vicsek, T.

    2018-02-01

    The structure of interactions in most animal and human societies can be best represented by complex hierarchical networks. In order to maintain close-to-optimal function both stability and adaptability are necessary. Here we investigate the stability of hierarchical networks that emerge from the simulations of an organization type with an efficiency function reminiscent of the Hamiltonian of spin glasses. Using this quantitative approach we find a number of expected (from everyday observations) and highly non-trivial results for the obtained locally optimal networks, including, for example: (i) stability increases with growing efficiency and level of hierarchy; (ii) the same perturbation results in a larger change for more efficient states; (iii) networks with a lower level of hierarchy become more efficient after perturbation; (iv) due to the huge number of possible optimal states only a small fraction of them exhibit resilience and, finally, (v) ‘attacks’ targeting the nodes selectively (regarding their position in the hierarchy) can result in paradoxical outcomes.

  17. Two-dimensional colloidal fluids exhibiting pattern formation.

    Science.gov (United States)

    Chacko, Blesson; Chalmers, Christopher; Archer, Andrew J

    2015-12-28

    Fluids with competing short range attraction and long range repulsive interactions between the particles can exhibit a variety of microphase separated structures. We develop a lattice-gas (generalised Ising) model and analyse the phase diagram using Monte Carlo computer simulations and also with density functional theory (DFT). The DFT predictions for the structures formed are in good agreement with the results from the simulations, which occur in the portion of the phase diagram where the theory predicts the uniform fluid to be linearly unstable. However, the mean-field DFT does not correctly describe the transitions between the different morphologies, which the simulations show to be analogous to micelle formation. We determine how the heat capacity varies as the model parameters are changed. There are peaks in the heat capacity at state points where the morphology changes occur. We also map the lattice model onto a continuum DFT that facilitates a simplification of the stability analysis of the uniform fluid.

  18. Allocentric spatial learning and memory deficits in Down syndrome.

    Directory of Open Access Journals (Sweden)

    Pamela A Banta Lavenex

    2015-02-01

    Full Text Available Studies have shown that persons with Down Syndrome (DS exhibit relatively poor language capacities, and impaired verbal and visuoperceptual memory, whereas their visuospatial memory capacities appear comparatively spared. Individuals with DS recall better where an object was previously seen than what object was previously seen. However, most of the evidence concerning preserved visuospatial memory comes from tabletop or computerized experiments which are biased towards testing egocentric (viewpoint-dependent spatial representations. Accordingly, allocentric (viewpoint-independent spatial learning and memory capacities may not be necessary to perform these tasks. Thus, in order to more fully characterize the spatial capacities of individuals with DS, allocentric processes underlying real-world navigation must also be investigated. We tested 20 participants with DS and 16 mental age-matched, typically developing (TD children in a real-world, allocentric spatial memory task. During local cue (LC trials, participants had to locate three rewards marked by local color cues, among 12 locations distributed in a 4 m X 4 m arena. During allocentric spatial (AS trials, participants had to locate the same three rewards, in absence of local cues, based on their relations to distal environmental cues. All TD participants chose rewarded locations in LC and AS trials at above chance level. In contrast, although all but one of the participants with DS exhibited a preference for the rewarded locations in LC trials, only 50% of participants with DS chose the rewarded locations at above chance level in AS trials. As a group, participants with DS performed worse than TD children on all measures of task performance. These findings demonstrate that individuals with DS are impaired at using an allocentric spatial representation to learn and remember discrete locations in a controlled environment, suggesting persistent and pervasive deficits in hippocampus

  19. Discrimination? - Exhibition of posters

    OpenAIRE

    Jakimovska, Jana

    2017-01-01

    Participation in the exhibition with the students form the Art Academy. The exhibition consisted of 15 posters tackling the subjects of hate speech and discrimination. The exhibition happened thanks to the invitation of the Faculty of Law at UGD, and it was a part of a larger event of launching books on the aforementioned subjects.

  20. Ultra-High Pressure Homogenization improves oxidative stability and interfacial properties of soy protein isolate-stabilized emulsions.

    Science.gov (United States)

    Fernandez-Avila, C; Trujillo, A J

    2016-10-15

    Ultra-High Pressure Homogenization (100-300MPa) has great potential for technological, microbiological and nutritional aspects of fluid processing. Its effect on the oxidative stability and interfacial properties of oil-in-water emulsions prepared with 4% (w/v) of soy protein isolate and soybean oil (10 and 20%, v/v) were studied and compared to emulsions treated by conventional homogenization (15MPa). Emulsions were characterized by particle size, emulsifying activity index, surface protein concentration at the interface and by transmission electron microscopy. Primary and secondary lipid oxidation products were evaluated in emulsions upon storage. Emulsions with 20% oil treated at 100 and 200MPa exhibited the most oxidative stability due to higher amount of oil and protein surface load at the interface. This manuscript addresses the improvement in oxidative stability in emulsions treated by UHPH when compared to conventional emulsions. Copyright © 2016 Elsevier Ltd. All rights reserved.

  1. Intermediate-term medium-range earthquake prediction algorithm M8: A new spatially stabilized application in Italy

    International Nuclear Information System (INIS)

    Romashkova, L.L.; Kossobokov, V.G.; Peresan, A.; Panza, G.F.

    2001-12-01

    A series of experiments, based on the intermediate-term earthquake prediction algorithm M8, has been performed for the retrospective simulation of forward predictions in the Italian territory, with the aim to design an experimental routine for real-time predictions. These experiments evidenced two main difficulties for the application of M8 in Italy. The first one is due to the fact that regional catalogues are usually limited in space. The second one concerns certain arbitrariness and instability, with respect to the positioning of the circles of investigation. Here we design a new scheme for the application of the algorithm M8, which is less subjective and less sensitive to the position of the circles of investigation. To perform this test, we consider a recent revision of the Italian catalogue, named UCI2001, composed by CCI1996, NEIC and ALPOR data for the period 1900-1985, and updated with the NEIC reduces the spatial heterogeneity of the data at the boundaries of Italy. The new variant of the M8 algorithm application reduces the number of spurious alarms and increases the reliability of predictions. As a result, three out of four earthquakes with magnitude M max larger than 6.0 are predicted in the retrospective simulation of the forward prediction, during the period 1972-2001, with a space-time volume of alarms comparable to that obtained with the non-stabilized variant of the M8 algorithm in Italy. (author)

  2. EXHIBITION: Accelerated Particles

    CERN Multimedia

    2004-01-01

    http://www.cern.ch/cern50/ An exhibition of plastic arts and two evenings of performances by sound and visual artists as part of CERN's fiftieth anniversary celebrations. The fiftieth anniversary of a world famous organization like CERN, an international laboratory specializing in fundamental research, is a cause for celebration. Since March this year, Geneva and neighbouring parts of France have been the venues for a wealth of small and large-scale events, which will continue until November. Given CERN's location in the commune of Meyrin, the ForuMeyrin is hosting two "salons" consisting of an exhibition of plastic arts and evenings of music and visual arts performances with the collective title of "Accelerated Particles". Several works will be exhibited and performed. Salon des matières: An exhibition of plastic arts Until Wednesday 3 November 2004. Tuesdays to Fridays: 4.00 p.m. to 7.00 p.m. Saturdays: 2.00 p.m. to 6.00 p.m. Doors open late on the evening of the performances. Salon des ...

  3. Delay-enhanced stability and stochastic resonance in perception bistability under non-Gaussian noise

    International Nuclear Information System (INIS)

    Yang, Tao; Zeng, Chunhua; Liu, Ruifen; Wang, Hua; Mei, Dongcheng

    2015-01-01

    In this paper we investigate the effect of time delay in an attractor network model of perception bistability driven by non-Gaussian noise. Using delay Langevin and Fokker–Planck approaches, the theoretical analysis of the model is presented. It is found that the mean first-passage time (MFPT) as a function of the time delay exhibits a maximum, which is identified as the characteristic of the delay-enhanced stability of the system. This is different to the case of noise-enhanced stability. The non-Gaussian noise-enhanced stability of the system is also analyzed. The signal-to-noise ratio (SNR) as a function of the noise intensity exhibits a maximum. This maximum implies the identifying characteristic of stochastic resonance (SR), and the time delay and non-Gaussian noise can enhance the SR phenomenon. (paper)

  4. Exhibiting the Human/Exhibiting the Cyborg: “Who Am I?”

    Directory of Open Access Journals (Sweden)

    Sophia C. Vackimes

    2013-08-01

    Full Text Available The role of the museum in shaping our relationship to science and technology, particularly cyborgization, is illuminated by a close examination of the Who Am I permanent exhibition in the Wellcome Wing of the Science Museum of London. This innovative exhibition raises real questions both about the human-technology-science relationship but also about museography. In the context of the history and current practices of museums engaging contemporary technological developments the evidence suggest that even as the Who am I? exhibit did break somewhat from previous approaches, especially the didactic presentation of the socially useful, it has not changed the feld as a whole.

  5. Continuous time modelling of dynamical spatial lattice data observed at sparsely distributed times

    DEFF Research Database (Denmark)

    Rasmussen, Jakob Gulddahl; Møller, Jesper

    2007-01-01

    Summary. We consider statistical and computational aspects of simulation-based Bayesian inference for a spatial-temporal model based on a multivariate point process which is only observed at sparsely distributed times. The point processes are indexed by the sites of a spatial lattice......, and they exhibit spatial interaction. For specificity we consider a particular dynamical spatial lattice data set which has previously been analysed by a discrete time model involving unknown normalizing constants. We discuss the advantages and disadvantages of using continuous time processes compared...... with discrete time processes in the setting of the present paper as well as other spatial-temporal situations....

  6. Role of anisotropy in determining stability of electrodeposition at solid-solid interfaces

    Science.gov (United States)

    Ahmad, Zeeshan; Viswanathan, Venkatasubramanian

    2017-10-01

    We investigate the stability of electrodeposition at solid-solid interfaces for materials exhibiting an anisotropic mechanical response. The stability of electrodeposition or resistance to the formation of dendrites is studied within a linear stability analysis. The deformation and stress equations are solved using the Stroh formalism and faithfully recover the boundary conditions at the interface. The stability parameter is used to quantify the stability of different solid-solid interfaces incorporating the full anisotropy of the elastic tensor of the two materials. Results show a high degree of variability in the stability parameter depending on the crystallographic orientation of the solids in contact, and point to opportunities for exploiting this effect in developing Li metal anodes.

  7. Electrostatic stability of electron-positron plasmas in dipole geometry

    OpenAIRE

    Mishchenko, Alexey; Plunk, Gabriel; Helander, Per

    2017-01-01

    The electrostatic stability of electron-positron plasmas is investigated in the point-dipole and Z-pinch limits of dipole geometry. The kinetic dispersion relation for sub-bounce-frequency instabilities is derived and solved. For the zero-Debye-length case, the stability diagram is found to exhibit singular behavior. However, when the Debye length is non-zero, a fluid mode appears, which resolves the observed singularity, and also demonstrates that both the temperature and density gradients c...

  8. Evaluation test on stability of high temperature strain gage

    Energy Technology Data Exchange (ETDEWEB)

    Sato, Toshimi (Kyowa Electronic Instruments Co. Ltd., Tokyo (Japan)); Ito, Haruhiko; Tanaka, Isao; Komori, Yoshihiro

    1983-08-01

    This report deals with the results on a stability test of high temperature strain gage which is utilized for development of the Stethoscope for OGL - 1 Components in Elevated Temperature Services (ab. SOCETS). The test has proved that the weldable strain gage (KHC - 20 - G5) exhibits excellent stability at 500/sup 0/C during 3000 to 4000 hours service and can be applied sufficiently to evaluate integrity of OGL - 1 high temperature pipings and others.

  9. Evaluation test on stability of high temperature strain gage

    International Nuclear Information System (INIS)

    Sato, Toshimi; Ito, Haruhiko; Tanaka, Isao; Komori, Yoshihiro.

    1983-01-01

    This report deals with the results on a stability test of high temperature strain gage which is utilized for development of the Stethoscope for OGL - 1 Components in Elevated Temperature Services (ab. SOCETS). The test has proved that the weldable strain gage (KHC - 20 - G5) exhibits excellent stability at 500 0 C during 3000 to 4000 hours service and can be applied sufficiently to evaluate integrity of OGL - 1 high temperature pipings and others. (author)

  10. Application of an imaging system to a museum exhibition for developing interactive exhibitions

    Science.gov (United States)

    Miyata, Kimiyoshi; Inoue, Yuka; Takiguchi, Takahiro; Tsumura, Norimichi; Nakaguchi, Toshiya; Miyake, Yoichi

    2009-10-01

    In the National Museum of Japanese History, 215,759 artifacts are stored and used for research and exhibitions. In museums, due to the limitation of space in the galleries, a guidance system is required to satisfy visitors' needs and to enhance their understanding of the artifacts. We introduce one exhibition using imaging technology to improve visitors' understanding of a kimono (traditional Japanese clothing) exhibition. In the imaging technology introduced, one data projector, one display with touch panel interface, and magnifiers were used as exhibition tools together with a real kimono. The validity of this exhibition method was confirmed by results from a visitors' interview survey. Second, to further develop the interactive guidance system, an augmented reality system that consisted of cooperation between the projector and a digital video camera was also examined. A white paper board in the observer's hand was used as a projection screen and also as an interface to control the images projected on the board. The basic performance of the proposed system was confirmed; however continuous development was necessary for applying the system to actual exhibitions.

  11. The Stability, Sustained Release and Cellular Antioxidant Activity of Curcumin Nanoliposomes

    Directory of Open Access Journals (Sweden)

    Xing Chen

    2015-08-01

    Full Text Available Curcumin is a multifunctional and natural agent considered to be pharmacologically safe. However, its application in the food and medical industry is greatly limited by its poor water solubility, physicochemical instability and inadequate bioavailability. Nanoliposome encapsulation could significantly enhance the solubility and stability of curcumin. Curcumin nanoliposomes exhibited good physicochemical properties (entrapment efficiency = 57.1, particle size = 68.1 nm, polydispersity index = 0.246, and zeta potential = −3.16 mV. Compared with free curcumin, curcumin nanoliposomes exhibited good stability against alkaline pH and metal ions as well as good storage stability at 4 °C. Curcumin nanoliposomes also showed good sustained release properties. Compared with free curcumin, curcumin nanoliposomes presented an equal cellular antioxidant activity, which is mainly attributed to its lower cellular uptake as detected by fluorescence microscopy and flow cytometry. This study provide theoretical and practical guides for the further application of curcumin nanoliposomes.

  12. Exhibition; Image display agency

    International Nuclear Information System (INIS)

    Normazlin Ismail

    2008-01-01

    This article touches on the role of Malaysian Nuclear Agency as nuclear research institutions to promote, develop and encourage the peaceful uses of nuclear technology in its agricultural, medical, manufacturing, industrial, health and environment for the development of the country running successfully. Maturity of Malaysian Nuclear Agency in dealing with nuclear technology that are very competitive and globalization cannot be denied. On this basis Malaysian Nuclear Agency was given the responsibility to strengthen the nuclear technology in Malaysia. One way is through an exhibition featuring the research, discoveries and new technology products of the nuclear technology. Through this exhibition is to promote the nuclear technology and introduce the image of the agency in the public eye. This article also states a number of exhibits entered by the Malaysian Nuclear Agency and achievements during the last exhibition. Authors hope that the exhibition can be intensified further in the future.

  13. Penultimate modeling of spatial extremes: statistical inference for max-infinitely divisible processes

    KAUST Repository

    Huser, Raphaë l; Opitz, Thomas; Thibaud, Emeric

    2018-01-01

    Extreme-value theory for stochastic processes has motivated the statistical use of max-stable models for spatial extremes. However, fitting such asymptotic models to maxima observed over finite blocks is problematic when the asymptotic stability

  14. An approach to stability analysis of spatial xenon oscillations in WWER-1000 reactors

    International Nuclear Information System (INIS)

    Parhizkari, H.; Aghaie, M.; Zolfaghari, A.; Minuchehr, A.

    2015-01-01

    Highlights: • The multipoint methodology is developed for xenon oscillation in the BNPP. • The axial, radial and azimuthal offsets are calculated in the BOC and EOC. • It is shown that the all of oscillation modes are safe in the BOC. • The axial oscillation is not safe in the EOC and needs governor control system. • The multipoint kinetics show good agreement for spatial oscillations. - Abstract: Spatial power oscillations due to spatial distribution of xenon transient are well known as xenon oscillation in large reactors. Xenon-induced spatial power oscillations occur as a result of rapid perturbations to power distribution that cause the xenon and iodine distribution to be out of phase with the perturbed power distribution. This results in a shift in xenon and iodine distributions that causes the power distribution to change in an opposite direction from the initial perturbation. In this paper xenon-induced power oscillation is described by a system of differential equations with non-linearity between xenon and flux distributions; the dynamics of process is described by a discrete distributed parameter model, with the neutron flux, the delayed neutrons, the core temperature and the xenon and iodine concentrations as the “states” of the system. It is shown that it is possible to describe the discrete distributed-parameter as a set of coupled point-reactor models. It is also shown that using this scheme it is possible to analyze the control aspects of a multi-section large core reactor by treating only two adjacent sections of the core. To illustrate the capability and efficiency of the proposed scheme Bushehr Nuclear Power Plant, BNPP, which is a WWER-1000 reactor, is chosen to show the performance of the methodology. The axial, azimuthal and radial power oscillation at the beginning of cycle, BOC, and the end of cycle, EOC, for BNPP are investigated; the results are in good agreement with safety analysis report of the reference plant

  15. Peripheral vision benefits spatial learning by guiding eye movements.

    Science.gov (United States)

    Yamamoto, Naohide; Philbeck, John W

    2013-01-01

    The loss of peripheral vision impairs spatial learning and navigation. However, the mechanisms underlying these impairments remain poorly understood. One advantage of having peripheral vision is that objects in an environment are easily detected and readily foveated via eye movements. The present study examined this potential benefit of peripheral vision by investigating whether competent performance in spatial learning requires effective eye movements. In Experiment 1, participants learned room-sized spatial layouts with or without restriction on direct eye movements to objects. Eye movements were restricted by having participants view the objects through small apertures in front of their eyes. Results showed that impeding effective eye movements made subsequent retrieval of spatial memory slower and less accurate. The small apertures also occluded much of the environmental surroundings, but the importance of this kind of occlusion was ruled out in Experiment 2 by showing that participants exhibited intact learning of the same spatial layouts when luminescent objects were viewed in an otherwise dark room. Together, these findings suggest that one of the roles of peripheral vision in spatial learning is to guide eye movements, highlighting the importance of spatial information derived from eye movements for learning environmental layouts.

  16. Kashi and Cosmos: Spatial manifestation and the five pilgrimage journeys of Banaras

    OpenAIRE

    Singh, Rana P.B., PhD, FJF, FAAI, FACLA; Rana, Pravin S

    2016-01-01

    Historically, Hindu rituals, sacred journeys, festivities, deities and their symmetrical links, have come together to form sacred spatial systems that are still observed by both pilgrims and devotees. These pilgrimage traditions are deeply rooted in local space / place, as well as in the cultural inheritance and mentality of their adherents. This structure is reflected symbolically in the spatial frame of Hinduism in which both complexity and temporal stability meet, mediating between people ...

  17. Spatial evolutionary games with weak selection.

    Science.gov (United States)

    Nanda, Mridu; Durrett, Richard

    2017-06-06

    Recently, a rigorous mathematical theory has been developed for spatial games with weak selection, i.e., when the payoff differences between strategies are small. The key to the analysis is that when space and time are suitably rescaled, the spatial model converges to the solution of a partial differential equation (PDE). This approach can be used to analyze all [Formula: see text] games, but there are a number of [Formula: see text] games for which the behavior of the limiting PDE is not known. In this paper, we give rules for determining the behavior of a large class of [Formula: see text] games and check their validity using simulation. In words, the effect of space is equivalent to making changes in the payoff matrix, and once this is done, the behavior of the spatial game can be predicted from the behavior of the replicator equation for the modified game. We say predicted here because in some cases the behavior of the spatial game is different from that of the replicator equation for the modified game. For example, if a rock-paper-scissors game has a replicator equation that spirals out to the boundary, space stabilizes the system and produces an equilibrium.

  18. [GLIATILIN CORRECTION OF WORKING AND REFERENCE SPATIAL MEMORY IMPAIRMENT IN AGED RATS].

    Science.gov (United States)

    Tyurenkov, I N; Volotova, E V; Kurkin, D V

    2015-01-01

    This work was aimed at evaluating the influence of gliatilin administration on the spatial memory in aged rats. Cognitive function and spatial memory in animals was evaluated using radial (8-beam) maze test. Errors of working spatial memory and reference memory were used as indicators of impaired cognitive function. It was found that aged (24-month) rats compared with younger (6-months) age group exhibited cognitive impairment, as manifested by deterioration of short- and long-term memory processes. Course administration of gliatilin in rats of the older age group at a dose of 100 mg/kg resulted in significant improvement of the working and reference spatial memory in aged rats.

  19. Effects of a cognitive dual task on variability and local dynamic stability in sustained repetitive arm movements using principal component analysis: a pilot study.

    Science.gov (United States)

    Longo, Alessia; Federolf, Peter; Haid, Thomas; Meulenbroek, Ruud

    2018-06-01

    In many daily jobs, repetitive arm movements are performed for extended periods of time under continuous cognitive demands. Even highly monotonous tasks exhibit an inherent motor variability and subtle fluctuations in movement stability. Variability and stability are different aspects of system dynamics, whose magnitude may be further affected by a cognitive load. Thus, the aim of the study was to explore and compare the effects of a cognitive dual task on the variability and local dynamic stability in a repetitive bimanual task. Thirteen healthy volunteers performed the repetitive motor task with and without a concurrent cognitive task of counting aloud backwards in multiples of three. Upper-body 3D kinematics were collected and postural reconfigurations-the variability related to the volunteer's postural change-were determined through a principal component analysis-based procedure. Subsequently, the most salient component was selected for the analysis of (1) cycle-to-cycle spatial and temporal variability, and (2) local dynamic stability as reflected by the largest Lyapunov exponent. Finally, end-point variability was evaluated as a control measure. The dual cognitive task proved to increase the temporal variability and reduce the local dynamic stability, marginally decrease endpoint variability, and substantially lower the incidence of postural reconfigurations. Particularly, the latter effect is considered to be relevant for the prevention of work-related musculoskeletal disorders since reduced variability in sustained repetitive tasks might increase the risk of overuse injuries.

  20. Characterization and stability studies of emulsion systems containing pumice

    Directory of Open Access Journals (Sweden)

    Marilene Estanqueiro

    2014-04-01

    Full Text Available Emulsions are the most common form of skin care products. However, these systems may exhibit some instability. Therefore, when developing emulsions for topical application it is interesting to verify whether they have suitable physical and mechanical characteristics and further assess their stability. The aim of this work was to study the stability of emulsion systems, which varied in the proportion of the emulsifying agent cetearyl alcohol (and sodium lauryl sulfate (and sodium cetearyl sulfate (LSX, the nature of the oily phase (decyl oleate, cyclomethicone or dimethicone and the presence or absence of pumice (5% w/w. While maintaining the samples at room temperature, rheology studies, texture analysis and microscopic observation of formulations with and without pumice were performed. Samples were also submitted to an accelerated stability study by centrifugation and to a thermal stress test. Through the testing, it was found that the amount of emulsifying agent affects the consistency and textural properties such as firmness and adhesiveness. So, formulations containing LSX (5% w/w and decyl oleate or dimethicone as oily phase had a better consistency and remained stable with time, so exhibited the best features to be used for skin care products.

  1. Dissociation of spatial memory systems in Williams syndrome.

    Science.gov (United States)

    Bostelmann, Mathilde; Fragnière, Emilie; Costanzo, Floriana; Di Vara, Silvia; Menghini, Deny; Vicari, Stefano; Lavenex, Pierre; Lavenex, Pamela Banta

    2017-11-01

    Williams syndrome (WS), a genetic deletion syndrome, is characterized by severe visuospatial deficits affecting performance on both tabletop spatial tasks and on tasks which assess orientation and navigation. Nevertheless, previous studies of WS spatial capacities have ignored the fact that two different spatial memory systems are believed to contribute parallel spatial representations supporting navigation. The place learning system depends on the hippocampal formation and creates flexible relational representations of the environment, also known as cognitive maps. The spatial response learning system depends on the striatum and creates fixed stimulus-response representations, also known as habits. Indeed, no study assessing WS spatial competence has used tasks which selectively target these two spatial memory systems. Here, we report that individuals with WS exhibit a dissociation in their spatial abilities subserved by these two memory systems. As compared to typically developing (TD) children in the same mental age range, place learning performance was impaired in individuals with WS. In contrast, their spatial response learning performance was facilitated. Our findings in individuals with WS and TD children suggest that place learning and response learning interact competitively to control the behavioral strategies normally used to support human spatial navigation. Our findings further suggest that the neural pathways supporting place learning may be affected by the genetic deletion that characterizes WS, whereas those supporting response learning may be relatively preserved. The dissociation observed between these two spatial memory systems provides a coherent theoretical framework to characterize the spatial abilities of individuals with WS, and may lead to the development of new learning strategies based on their facilitated response learning abilities. © 2017 Wiley Periodicals, Inc.

  2. Three caveats for linear stability theory: Rayleigh-Benard convection

    International Nuclear Information System (INIS)

    Greenside, H.S.

    1984-06-01

    Recent theories and experiments challenge the applicability of linear stability theory near the onset of buoyancy-driven (Rayleigh-Benard) convection. This stability theory, based on small perturbations of infinite parallel rolls, is found to miss several important features of the convective flow. The reason is that the lateral boundaries have a profound influence on the possible wave numbers and flow patterns even for the largest cells studied. Also, the nonlinear growth of incoherent unstable modes distorts the rolls, leading to a spatially disordered and sometimes temporally nonperiodic flow. Finally, the relation of the skewed varicose instability to the onset of turbulence (nonperiodic time dependence) is examined. Linear stability theory may not suffice to predict the onset of time dependence in large cells close to threshold

  3. Effect of sorbitol and glycerol on the stability of trypsin and difference between their stabilization effects in the various solvents.

    Science.gov (United States)

    Pazhang, Mohammad; Mehrnejad, Faramarz; Pazhang, Yaghub; Falahati, Hanieh; Chaparzadeh, Nader

    2016-01-01

    The effect of glycerol and sorbitol on the stability of porcine pancreas trypsin was investigated in this work. Molecular dynamics simulation and thermostability results showed that trypsin has two flexible regions, and polyols (sorbitol and glycerol) stabilize the enzyme by decreasing the flexibility of these regions. Radial distribution function results exhibited that sorbitol and glycerol were excluded from the first water layer of the enzyme, therefore decrease the flexibility of the regions by preferential exclusion. Also, results showed that the stabilization effect of sorbitol is more than glycerol. This observation could be because of the larger decrease in the fluctuations of trypsin in the presence of sorbitol. We also examined the role of solvent's hydrophobicity in enzyme stabilization by sorbitol and glycerol. To do so, the thermostability of trypsin was evaluated in the presence of solvents with different hydrophobicity (methanol, ethanol, isopropanol and n-propanol) in addition to the polyols. Our results depicted that glycerol is a better stabilizer than sorbitol in the presence of hydrophobic solvents (n-propanol), whereas sorbitol is a better stabilizer than glycerol in the presence of hydrophilic solvents (methanol). © 2015 International Union of Biochemistry and Molecular Biology, Inc.

  4. Nanoscale zero-valent iron (nZVI) synthesis in a Mg-aminoclay solution exhibits increased stability and reactivity for reductive decontamination

    DEFF Research Database (Denmark)

    Hwang, Yuhoon; Lee, Young-Chul; Mines, Paul D.

    2014-01-01

    Nanoscale zero-valent iron (nZVI) has often been explored as a reductant for detoxification of pollutants in environmental clean-ups. Despite the large surface area and superior reactivity of nZVI, its limited stability is a major obstacle in applying nZVI for in situ subsurface remediation, e......ZVI particles with higher crystallinity were produced. Stability of nZVI particles were evaluated using a sedimentation test and a dynamic light scattering technique. The characteristic time increased from 6.71 to 83.8 min, and particle (aggregate diameter) size decreased from 5132 to 186 nm with increasing...

  5. Modeling spatial processes with unknown extremal dependence class

    KAUST Repository

    Huser, Raphaël G.

    2017-03-17

    Many environmental processes exhibit weakening spatial dependence as events become more extreme. Well-known limiting models, such as max-stable or generalized Pareto processes, cannot capture this, which can lead to a preference for models that exhibit a property known as asymptotic independence. However, weakening dependence does not automatically imply asymptotic independence, and whether the process is truly asymptotically (in)dependent is usually far from clear. The distinction is key as it can have a large impact upon extrapolation, i.e., the estimated probabilities of events more extreme than those observed. In this work, we present a single spatial model that is able to capture both dependence classes in a parsimonious manner, and with a smooth transition between the two cases. The model covers a wide range of possibilities from asymptotic independence through to complete dependence, and permits weakening dependence of extremes even under asymptotic dependence. Censored likelihood-based inference for the implied copula is feasible in moderate dimensions due to closed-form margins. The model is applied to oceanographic datasets with ambiguous true limiting dependence structure.

  6. Implications of treadmilling for the stability and polarity of actin and tubulin polymers in vivo.

    Science.gov (United States)

    Kirschner, M W

    1980-07-01

    In this report, we examine how the cell can selectively stabilize anchored filaments and suppress spontaneous filament assembly. Because microtubules and actin filaments have an organized distribution in cells, the cell must have a mechanism for suppressing spontaneous and random polymerization. Though the mechanism for suppressing spontaneous polymerization is unknown, an unusual property of these filaments has been demonstrated recently, i.e., under steady-stae conditions, in vitro actin filaments and microtubules can exhibit a flux of subunits through the polymers called "treadmilling." In vivo, however, most, if not all, of these polymers are attached at one end to specific structures and treadmilling should not occur. The function of treadmilling in vivo is, therefore, unclear at present. However, as shown here, the same physicochemical property of coupling assembly to ATP or GTP hydrolysis that leads to treadmilling in vitro can act to selectively stabilize anchored polymers in vivo. I show here that the theory of treadmilling implies that the concentration of subunits necessary for assembly of the nonanchored polymer will in general be higher than the concentration necessary for the assembly of polymers anchored with a specific polarity. This disparity in the monomer concentrations required for assembly can lead to a selective stabilization of anchored polymers and complete suppression of spontaneous polymerization at apparent equilibrium in vivo. It is possible, therefore, that the phenomenon of treadmilling is an in vitro manifestation of a mechanism designed to use ATP or GTP hydrolysis to control the spatial organization of filaments in the cell.

  7. A composite likelihood approach for spatially correlated survival data

    Science.gov (United States)

    Paik, Jane; Ying, Zhiliang

    2013-01-01

    The aim of this paper is to provide a composite likelihood approach to handle spatially correlated survival data using pairwise joint distributions. With e-commerce data, a recent question of interest in marketing research has been to describe spatially clustered purchasing behavior and to assess whether geographic distance is the appropriate metric to describe purchasing dependence. We present a model for the dependence structure of time-to-event data subject to spatial dependence to characterize purchasing behavior from the motivating example from e-commerce data. We assume the Farlie-Gumbel-Morgenstern (FGM) distribution and then model the dependence parameter as a function of geographic and demographic pairwise distances. For estimation of the dependence parameters, we present pairwise composite likelihood equations. We prove that the resulting estimators exhibit key properties of consistency and asymptotic normality under certain regularity conditions in the increasing-domain framework of spatial asymptotic theory. PMID:24223450

  8. A composite likelihood approach for spatially correlated survival data.

    Science.gov (United States)

    Paik, Jane; Ying, Zhiliang

    2013-01-01

    The aim of this paper is to provide a composite likelihood approach to handle spatially correlated survival data using pairwise joint distributions. With e-commerce data, a recent question of interest in marketing research has been to describe spatially clustered purchasing behavior and to assess whether geographic distance is the appropriate metric to describe purchasing dependence. We present a model for the dependence structure of time-to-event data subject to spatial dependence to characterize purchasing behavior from the motivating example from e-commerce data. We assume the Farlie-Gumbel-Morgenstern (FGM) distribution and then model the dependence parameter as a function of geographic and demographic pairwise distances. For estimation of the dependence parameters, we present pairwise composite likelihood equations. We prove that the resulting estimators exhibit key properties of consistency and asymptotic normality under certain regularity conditions in the increasing-domain framework of spatial asymptotic theory.

  9. Effects of different dairy ingredients on the rheological behaviour and stability of hot cheese emulsions

    DEFF Research Database (Denmark)

    Kelimu, Abulimiti; Felix da Silva, Denise; Geng, Xiaolu

    2017-01-01

    The influence of sodium caseinate (SC), butter milk powder (BMP) and their combinations on particle size, rheological properties, emulsion stability and microstructure of hot cheese emulsions made from mixtures of Cheddar and soft white cheese was studied. All emulsions exhibited shear-thinning f......The influence of sodium caseinate (SC), butter milk powder (BMP) and their combinations on particle size, rheological properties, emulsion stability and microstructure of hot cheese emulsions made from mixtures of Cheddar and soft white cheese was studied. All emulsions exhibited shear......-thinning flow behaviour and increasing SC concentration (1–4%) led to an increase in particle size and a decrease in apparent viscosity. In contrast, increasing BMP concentration caused significant decrease in particle size and slightly reduced the apparent viscosity. Stability against creaming...

  10. Spatial Pattern, Transportation and Air Quality Nexus: The Case of Iskandar Malaysia

    Directory of Open Access Journals (Sweden)

    Azalia Mohd Yusop

    2016-09-01

    Full Text Available Spatial pattern, transportation, and air quality are three development entities which significantly affecting one another. This nexus exhibits the urbanization imprint accouter transportation generating air pollution as a reflection of spatial distribution. The integration among them is a vital part of development as it affects the societal living environment. It provides unfavorable air quality and directly cause health problems. The developing region of Iskandar Malaysia exhibits huge spatial distribution transformation accompanied by large percentage of urbanization rate, but seems less integration of land use and transportation planning which causes the exaggeration of air pollution. We carry out the research on the nexus of spatial distribution, transportation and air quality in Iskandar Malaysia by analyzing and evaluating the interconnectivity of these three entities. The spatial analysis and evaluation on the land use development pattern and spatial policy shows that the Iskandar development region are growing in the polycentric manners, where the spatial development policy drives the distributional growth of new sub-centers. We undertook a household-based travel survey that reveals the poly-centricity reflected by the de-concentration of workplaces which shifted from the single point towards multiple centers. On the other hand, this phenomenon has created a distributional traffic pattern amid the high dependency on the private vehicles of the citizens in Iskandar Malaysia. With a predominantly fossil fuel consuming vehicles, this has generated air pollution. Based on the traffic survey and the dependency of the citizens on private cars for their daily mobility, the concentration of air pollution is seemingly at risk. This research reflects that Iskandar Malaysia development region currently undergoes towards polycentric development with some new urban centers. We found that land use and transportation planning policies require serious

  11. Three-dimensional modelling of slope stability using the Local Factor of Safety concept

    Science.gov (United States)

    Moradi, Shirin; Huisman, Sander; Beck, Martin; Vereecken, Harry; Class, Holger

    2017-04-01

    Slope stability is governed by coupled hydrological and mechanical processes. The slope stability depends on the effective stress, which in turn depends on the weight of the soil and the matrix potential. Therefore, changes in water content and matrix potential associated with infiltration will affect slope stability. Most available models describing these coupled hydro-mechanical processes either rely on a one- or two-dimensional representation of hydrological and mechanical properties and processes, which obviously is a strong simplification in many applications. Therefore, the aim of this work is to develop a three-dimensional hydro-mechanical model that is able to capture the effect of spatial and temporal variability of both mechanical and hydrological parameters on slope stability. For this, we rely on DuMux, which is a free and open-source simulator for flow and transport processes in porous media that facilitates coupling of different model approaches and offers flexibility for model development. We use the Richards equation to model unsaturated water flow. The simulated water content and matrix potential distribution is used to calculate the effective stress. We only consider linear elasticity and solve for statically admissible fields of stress and displacement without invoking failure or the redistribution of post-failure stress or displacement. The Local Factor of Safety concept is used to evaluate slope stability in order to overcome some of the main limitations of commonly used methods based on limit equilibrium considerations. In a first step, we compared our model implementation with a 2D benchmark model that was implemented in COMSOL Multiphysics. In a second step, we present in-silico experiments with the newly developed 3D model to show the effect of slope morphology, spatial variability in hydraulic and mechanical material properties, and spatially variable soil depth on simulated slope stability. It is expected that this improved physically

  12. Explicit strong stability preserving multistep Runge–Kutta methods

    KAUST Repository

    Bresten, Christopher; Gottlieb, Sigal; Grant, Zachary; Higgs, Daniel; Ketcheson, David I.; Né meth, Adrian

    2015-01-01

    High-order spatial discretizations of hyperbolic PDEs are often designed to have strong stability properties, such as monotonicity. We study explicit multistep Runge-Kutta strong stability preserving (SSP) time integration methods for use with such discretizations. We prove an upper bound on the SSP coefficient of explicit multistep Runge-Kutta methods of order two and above. Numerical optimization is used to find optimized explicit methods of up to five steps, eight stages, and tenth order. These methods are tested on the linear advection and nonlinear Buckley-Leverett equations, and the results for the observed total variation diminishing and/or positivity preserving time-step are presented.

  13. Explicit strong stability preserving multistep Runge–Kutta methods

    KAUST Repository

    Bresten, Christopher

    2015-10-15

    High-order spatial discretizations of hyperbolic PDEs are often designed to have strong stability properties, such as monotonicity. We study explicit multistep Runge-Kutta strong stability preserving (SSP) time integration methods for use with such discretizations. We prove an upper bound on the SSP coefficient of explicit multistep Runge-Kutta methods of order two and above. Numerical optimization is used to find optimized explicit methods of up to five steps, eight stages, and tenth order. These methods are tested on the linear advection and nonlinear Buckley-Leverett equations, and the results for the observed total variation diminishing and/or positivity preserving time-step are presented.

  14. Stability of the Tonks–Langmuir discharge pre-sheath

    Energy Technology Data Exchange (ETDEWEB)

    Tskhakaya, D. D. [Fusion@ÖAW, Institute of Applied Physics, TU Wien, Wiedner Hauptstraße 8-10, 1040 Vienna (Austria); Kos, L. [LECAD Laboratory, Faculty of Mechanical Engineering, University of Ljubljana, SI-1000 Ljubljana (Slovenia); Tskhakaya, D. [Fusion@ÖAW, Institute of Applied Physics, TU Wien, Wiedner Hauptstraße 8-10, 1040 Vienna (Austria); Institute for Theoretical Physics, University of Innsbruck, A-6020 Innsbruck (Austria)

    2016-03-15

    The article formulates the stability problem of the plasma sheath in the Tonks–Langmuir discharge. Using the kinetic description of the ion gas, i.e., the stability of the potential shape in the quasi-neutral pre-sheath regarding the high and low frequency, the perturbations are investigated. The electrons are assumed to be Maxwell–Boltzmann distributed. Regarding high-frequency perturbations, the pre-sheath is shown to be stable. The stability problem regarding low-frequency perturbations can be reduced to an analysis of the “diffusion like” equation, which results in the instability of the potential distribution in the pre-sheath. By means of the Particle in Cell simulations, also the nonlinear stage of low frequency oscillations is investigated. Comparing the figure obtained with the figure for linear stage, one can find obvious similarity in the spatial-temporal behavior of the potential.

  15. Electrostatic stability of electron-positron plasmas in dipole geometry

    Science.gov (United States)

    Mishchenko, Alexey; Plunk, Gabriel G.; Helander, Per

    2018-04-01

    The electrostatic stability of electron-positron plasmas is investigated in the point-dipole and Z-pinch limits of dipole geometry. The kinetic dispersion relation for sub-bounce-frequency instabilities is derived and solved. For the zero-Debye-length case, the stability diagram is found to exhibit singular behaviour. However, when the Debye length is non-zero, a fluid mode appears, which resolves the observed singularity, and also demonstrates that both the temperature and density gradients can drive instability. It is concluded that a finite Debye length is necessary to determine the stability boundaries in parameter space. Landau damping is investigated at scales sufficiently smaller than the Debye length, where instability is absent.

  16. Stability of DIII-D high-performance, negative central shear discharges

    Science.gov (United States)

    Hanson, J. M.; Berkery, J. W.; Bialek, J.; Clement, M.; Ferron, J. R.; Garofalo, A. M.; Holcomb, C. T.; La Haye, R. J.; Lanctot, M. J.; Luce, T. C.; Navratil, G. A.; Olofsson, K. E. J.; Strait, E. J.; Turco, F.; Turnbull, A. D.

    2017-05-01

    Tokamak plasma experiments on the DIII-D device (Luxon et al 2005 Fusion Sci. Tech. 48 807) demonstrate high-performance, negative central shear (NCS) equilibria with enhanced stability when the minimum safety factor {{q}\\text{min}} exceeds 2, qualitatively confirming theoretical predictions of favorable stability in the NCS regime. The discharges exhibit good confinement with an L-mode enhancement factor H 89  =  2.5, and are ultimately limited by the ideal-wall external kink stability boundary as predicted by ideal MHD theory, as long as tearing mode (TM) locking events, resistive wall modes (RWMs), and internal kink modes are properly avoided or controlled. Although the discharges exhibit rotating TMs, locking events are avoided as long as a threshold minimum safety factor value {{q}\\text{min}}>2 is maintained. Fast timescale magnetic feedback control ameliorates RWM activity, expanding the stable operating space and allowing access to {β\\text{N}} values approaching the ideal-wall limit. Quickly growing and rotating instabilities consistent with internal kink mode dynamics are encountered when the ideal-wall limit is reached. The RWM events largely occur between the no- and ideal-wall pressure limits predicted by ideal MHD. However, evaluating kinetic contributions to the RWM dispersion relation results in a prediction of passive stability in this regime due to high plasma rotation. In addition, the ideal MHD stability analysis predicts that the ideal-wall limit can be further increased to {β\\text{N}}>4 by broadening the current profile. This path toward improved stability has the potential advantage of being compatible with the bootstrap-dominated equilibria envisioned for advanced tokamak (AT) fusion reactors.

  17. Superamphiphobic cotton fabrics with enhanced stability

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Bi, E-mail: xubi@dhu.edu.cn [National Engineering Research Center for Dyeing and Finishing of Textiles, Donghua University, Shanghai 201620 (China); Key Laboratory of Science & Technology of Eco-Textile, Ministry of Education, Donghua University, Shanghai 201620 (China); College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620 (China); Ding, Yinyan; Qu, Shaobo [College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620 (China); Cai, Zaisheng, E-mail: zshcai@dhu.edu [College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620 (China)

    2015-11-30

    Highlights: • Superamphiphobic cotton fabrics were prepared. • Water and hexadecane contact angels reach to 164.4° and 156.3°, respectively. • Nanoporous organically modified silica alcogel particles were synthesized. • The superamphiphobic cotton fabrics exhibit enhanced stability against abrasion, laundering and acid. - Abstract: Superamphiphobic cotton fabrics were prepared by alternately depositing organically modified silica alcogel (ormosil) particles onto chitosan precoated cotton fabrics and subsequent 1H, 1H, 2H, 2H-perfluorooctyltrimethoxysilane (PFOTMS) modification. Transmission electron microscopy and scanning electron microscopy images reveal that the ormosil particles display a fluffy, sponge-like nanoporous structure, and the entire cotton fiber surface is covered with highly porous networks. PFOTMS acts as not only a modifier to lower the surface energy of the cotton fabric but also a binder to enhance the coating stability against abrasion and washing. The treated cotton fabrics show highly liquid repellency with the water, cooking oil and hexadecane contact angels reaching to 164.4°, 160.1° and 156.3°, respectively. Meanwhile, the treated cotton fabrics exhibit good abrasion resistance and high laundering durability, which can withstand 10,000 cycles of abrasion and 30 cycles of machine wash without apparently changing the superamphiphobicity. The superamphiphobic cotton fabric also shows high acid stability, and can withstand 98% H{sub 2}SO{sub 4}. Moreover, the superamphiphobic coating has almost no influence on the other physical properties of the cotton fabrics including tensile strength, whiteness and air permeability. This durable non-wetting surface may provide a wide range of new applications in the future.

  18. Stabilized High Power Laser for Advanced Gravitational Wave Detectors

    International Nuclear Information System (INIS)

    Willke, B; Danzmann, K; Fallnich, C; Frede, M; Heurs, M; King, P; Kracht, D; Kwee, P; Savage, R; Seifert, F; Wilhelm, R

    2006-01-01

    Second generation gravitational wave detectors require high power lasers with several 100W of output power and with very low temporal and spatial fluctuations. In this paper we discuss possible setups to achieve high laser power and describe a 200W prestabilized laser system (PSL). The PSL noise requirements for advanced gravitational wave detectors will be discussed in general and the stabilization scheme proposed for the Advanced LIGO PSL will be described. Special emphasis will be given to the most demanding power stabilization requirements and new results (RIN ≤ 4x10 -9 /√Hz) will be presented

  19. Response of soil aggregate stability to storage time of soil samples

    International Nuclear Information System (INIS)

    Gerzabek, M.H.; Roessner, H.

    1993-04-01

    The aim of the present study was to investigate the well known phenomenon of changing aggregate stability values as result of soil sample storage. In order to evaluate the impact of soil microbial activity, the soil sample was split into three subsamples. Two samples were sterilized by means of chloroform fumigation and gamma irradiation, respectively. However, the aggregate stability measurements at three different dates were not correlated with the microbial activity (dehydrogenase activity). The moisture content of the aggregate samples seems to be of higher significance. Samples with lower moisture content (range: 0.4 to 1.9%) exhibited higher aggregate stabilities. Thus, airdried aggregate samples without further treatment don't seem to be suitable for standardized stability measurements. (authors)

  20. The World of Virtual Exhibitions

    Directory of Open Access Journals (Sweden)

    Irena Eiselt

    2013-09-01

    Full Text Available EXTENDED ABSTRACTSpecial collections of the National and University Library (NUK hide a lot of items of precious value. The Slovenian cultural heritage is stored on paper or on other media as a part of the library’s Manuscripts, Incunabula and Rare Books Collection, Old Prints Collection, Maps and Pictorial Collection, Music Collection, Ephemera Collection, Serials Collection, and Slovenian Diaspora Publications Collection. Only a small part of the treasures is temporary revealed to the public on special exhibitions. The idea of virtual exhibitions of library treasures was born in 2005. The library aimed to exhibit precious items of special collections of high historical or artistic value. In 2008 the first two virtual exhibitions were created in-house offering access to the rich collections of old postcards of Ljubljana at the beginning of 20th century kept in the Maps and Pictorial Collection of NUK. They were soon followed by other virtual exhibitions. At the beginning they were organised in the same way as physical exhibitions, afterwards different programs were used for creation of special effects (for ex. 3D wall. About two years ago it was decided that the creation of virtual exhibitions will be simplified. Files of digitised and borndigital library materials in jpg format are imported to MS PowerPoint 2010. Each jpg file is now formatted by adding a frame, a description … to the slides which are saved as jpg files. The last step is the import of jpg files into Cooliris application used for NUK web exhibitions. In the paper the virtual exhibition design and creation, the technical point of view and criteria for the selection of exhibition content are explained following the example of the virtual exhibitions the Old Postcards of Ljubljana, Photo Ateliers in Slovenia, a collection of photographs Four Seasons by Fran Krašovec and photos of Post-Earthquake Ljubljana in 1895.

  1. Limited gene dispersal and spatial genetic structure as stabilizing factors in an ant-plant mutualism.

    Science.gov (United States)

    Malé, P-J G; Leroy, C; Humblot, P; Dejean, A; Quilichini, A; Orivel, J

    2016-12-01

    Comparative studies of the population genetics of closely associated species are necessary to properly understand the evolution of these relationships because gene flow between populations affects the partners' evolutionary potential at the local scale. As a consequence (at least for antagonistic interactions), asymmetries in the strength of the genetic structures of the partner populations can result in one partner having a co-evolutionary advantage. Here, we assess the population genetic structure of partners engaged in a species-specific and obligatory mutualism: the Neotropical ant-plant, Hirtella physophora, and its ant associate, Allomerus decemarticulatus. Although the ant cannot complete its life cycle elsewhere than on H. physophora and the plant cannot live for long without the protection provided by A. decemarticulatus, these species also have antagonistic interactions: the ants have been shown to benefit from castrating their host plant and the plant is able to retaliate against too virulent ant colonies. We found similar short dispersal distances for both partners, resulting in the local transmission of the association and, thus, inbred populations in which too virulent castrating ants face the risk of local extinction due to the absence of H. physophora offspring. On the other hand, we show that the plant populations probably experienced greater gene flow than did the ant populations, thus enhancing the evolutionary potential of the plants. We conclude that such levels of spatial structure in the partners' populations can increase the stability of the mutualistic relationship. Indeed, the local transmission of the association enables partial alignments of the partners' interests, and population connectivity allows the plant retaliation mechanisms to be locally adapted to the castration behaviour of their symbionts. © 2016 European Society For Evolutionary Biology. Journal of Evolutionary Biology © 2016 European Society For Evolutionary Biology.

  2. Shaping Watersheds Exhibit: An Interactive, Augmented Reality Sandbox for Advancing Earth Science Education

    Science.gov (United States)

    Reed, S. E.; Kreylos, O.; Hsi, S.; Kellogg, L. H.; Schladow, G.; Yikilmaz, M. B.; Segale, H.; Silverman, J.; Yalowitz, S.; Sato, E.

    2014-12-01

    One of the challenges involved in learning earth science is the visualization of processes which occur over large spatial and temporal scales. Shaping Watersheds is an interactive 3D exhibit developed with support from the National Science Foundation by a team of scientists, science educators, exhibit designers, and evaluation professionals, in an effort to improve public understanding and stewardship of freshwater ecosystems. The hands-on augmented reality sandbox allows users to create topographic models by shaping real "kinetic" sand. The exhibit is augmented in real time by the projection of a color elevation map and contour lines which exactly match the sand topography, using a closed loop of a Microsoft Kinect 3D camera, simulation and visualization software, and a data projector. When an object (such as a hand) is sensed at a particular height above the sand surface, virtual rain appears as a blue visualization on the surface and a flow simulation (based on a depth-integrated version of the Navier-Stokes equations) moves the water across the landscape. The blueprints and software to build the sandbox are freely available online (http://3dh2o.org/71/) under the GNU General Public License, together with a facilitator's guide and a public forum (with how-to documents and FAQs). Using these resources, many institutions (20 and counting) have built their own exhibits to teach a wide variety of topics (ranging from watershed stewardship, hydrology, geology, topographic map reading, and planetary science) in a variety of venues (such as traveling science exhibits, K-12 schools, university earth science departments, and museums). Additional exhibit extensions and learning modules are planned such as tsunami modeling and prediction. Moreover, a study is underway at the Lawrence Hall of Science to assess how various aspects of the sandbox (such as visualization color scheme and level of interactivity) affect understanding of earth science concepts.

  3. Persistent spatial information in the frontal eye field during object-based short-term memory.

    Science.gov (United States)

    Clark, Kelsey L; Noudoost, Behrad; Moore, Tirin

    2012-08-08

    Spatial attention is known to gate entry into visual short-term memory, and some evidence suggests that spatial signals may also play a role in binding features or protecting object representations during memory maintenance. To examine the persistence of spatial signals during object short-term memory, the activity of neurons in the frontal eye field (FEF) of macaque monkeys was recorded during an object-based delayed match-to-sample task. In this task, monkeys were trained to remember an object image over a brief delay, regardless of the locations of the sample or target presentation. FEF neurons exhibited visual, delay, and target period activity, including selectivity for sample location and target location. Delay period activity represented the sample location throughout the delay, despite the irrelevance of spatial information for successful task completion. Furthermore, neurons continued to encode sample position in a variant of the task in which the matching stimulus never appeared in their response field, confirming that FEF maintains sample location independent of subsequent behavioral relevance. FEF neurons also exhibited target-position-dependent anticipatory activity immediately before target onset, suggesting that monkeys predicted target position within blocks. These results show that FEF neurons maintain spatial information during short-term memory, even when that information is irrelevant for task performance.

  4. Increase in stability of cellulase immobilized on functionalized magnetic nanospheres

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Wenjuan [Department of Machine Intelligence and Systems Engineering, Faculty of Systems Engineering, Akita Prefectural University, Akita 015-0055 (Japan); Qiu, Jianhui, E-mail: qiu@akita-pu.ac.jp [Department of Machine Intelligence and Systems Engineering, Faculty of Systems Engineering, Akita Prefectural University, Akita 015-0055 (Japan); Feng, Huixia [College of Petrochemical Engineering, Lanzhou University of Technology, Lanzhou 730050 (China); Zang, Limin; Sakai, Eiichi [Department of Machine Intelligence and Systems Engineering, Faculty of Systems Engineering, Akita Prefectural University, Akita 015-0055 (Japan)

    2015-02-01

    Functionalized magnetic nanospheres were prepared by co-condensation of tetraethylorthosilicate with three different amino-silanes: 3-(2-aminoethylamino propyl)-triethoxysilane (AEAPTES), 3-(2-aminoethylamino propyl)-trimethoxysilane (AEAPTMES) and 3-aminopropyltriethoxysilane (APTES). Then three functionalized magnetic nanospheres were used as supports for immobilization of cellulase. The three functionalized magnetic nanospheres with core–shell morphologies exhibited higher capacity for cellulase immobilization than unfunctionalized magnetic nanospheres. The increasing of surface charge of functionalized magnetic nanospheres leads to an enhancement of the capacity of cellulase immobilization. Particularly, AEAPTMES with methoxy groups was favored to be hydrolyzed and grafted on unfunctionalized magnetic nanospheres than the others. AEAPTMES functionalized magnetic nanospheres with the highest zeta potential (29 mV) exhibited 87% activity recovery and the maximum amount of immobilized cellulase was 112 mg/g support at concentration of initial cellulase of 8 mg/mL. Immobilized cellulase on AEAPTMES functionalized magnetic nanospheres had higher temperature stability and broader pH stability than other immobilized cellulases and free cellulase. In particular, it can be used in about 40 °C, demonstrating the potential of biofuel production using this immobilized cellulase. - Highlights: • Three Amino-silane modified magnetic nanospheres were prepared. • Cellulase immobilized AEAPTMES functionalized magnetic nanospheres had higher temperature stability and broader pH stability than free cellulase. • The potential of biofuel production using this immobilized cellulase.

  5. Increase in stability of cellulase immobilized on functionalized magnetic nanospheres

    International Nuclear Information System (INIS)

    Zhang, Wenjuan; Qiu, Jianhui; Feng, Huixia; Zang, Limin; Sakai, Eiichi

    2015-01-01

    Functionalized magnetic nanospheres were prepared by co-condensation of tetraethylorthosilicate with three different amino-silanes: 3-(2-aminoethylamino propyl)-triethoxysilane (AEAPTES), 3-(2-aminoethylamino propyl)-trimethoxysilane (AEAPTMES) and 3-aminopropyltriethoxysilane (APTES). Then three functionalized magnetic nanospheres were used as supports for immobilization of cellulase. The three functionalized magnetic nanospheres with core–shell morphologies exhibited higher capacity for cellulase immobilization than unfunctionalized magnetic nanospheres. The increasing of surface charge of functionalized magnetic nanospheres leads to an enhancement of the capacity of cellulase immobilization. Particularly, AEAPTMES with methoxy groups was favored to be hydrolyzed and grafted on unfunctionalized magnetic nanospheres than the others. AEAPTMES functionalized magnetic nanospheres with the highest zeta potential (29 mV) exhibited 87% activity recovery and the maximum amount of immobilized cellulase was 112 mg/g support at concentration of initial cellulase of 8 mg/mL. Immobilized cellulase on AEAPTMES functionalized magnetic nanospheres had higher temperature stability and broader pH stability than other immobilized cellulases and free cellulase. In particular, it can be used in about 40 °C, demonstrating the potential of biofuel production using this immobilized cellulase. - Highlights: • Three Amino-silane modified magnetic nanospheres were prepared. • Cellulase immobilized AEAPTMES functionalized magnetic nanospheres had higher temperature stability and broader pH stability than free cellulase. • The potential of biofuel production using this immobilized cellulase

  6. Exhibition at the AAA library

    DEFF Research Database (Denmark)

    2013-01-01

    Sonnesgade 11 The exhibition at the AAA library presents selected work produced by students prior to the exhibition of installations in project and praxis constructing an archive at Sonnesgade 11. The exhibition at Sonnesgade 11 was the culmination of collaboration with SLETH architects and studio...

  7. Unifying dynamical and structural stability of equilibria

    Science.gov (United States)

    Arnoldi, Jean-François; Haegeman, Bart

    2016-09-01

    We exhibit a fundamental relationship between measures of dynamical and structural stability of linear dynamical systems-e.g. linearized models in the vicinity of equilibria. We show that dynamical stability, quantified via the response to external perturbations (i.e. perturbation of dynamical variables), coincides with the minimal internal perturbation (i.e. perturbations of interactions between variables) able to render the system unstable. First, by reformulating a result of control theory, we explain that harmonic external perturbations reflect the spectral sensitivity of the Jacobian matrix at the equilibrium, with respect to constant changes of its coefficients. However, for this equivalence to hold, imaginary changes of the Jacobian's coefficients have to be allowed. The connection with dynamical stability is thus lost for real dynamical systems. We show that this issue can be avoided, thus recovering the fundamental link between dynamical and structural stability, by considering stochastic noise as external and internal perturbations. More precisely, we demonstrate that a linear system's response to white-noise perturbations directly reflects the intensity of internal white-noise disturbance that it can accommodate before becoming stochastically unstable.

  8. Electrochemical stability of subnanometer Pt clusters

    DEFF Research Database (Denmark)

    Quinson, Jonathan; Röefzaad, Melanie; Deiana, Davide

    2018-01-01

    In the present work, the degradation of size-selected Pt nanoclusters is studied under electrochemical conditions. This model catalyst mimics carbon supported Pt nanoclusters and nanoparticles typically employed in proton exchange membrane fuel cells (PEMFCs). Insight into the early stage...... of degradation is given by high-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM) and confirmed by transmission electron microscopy (TEM). In contrast to common assumptions, it is demonstrated that even extremely small Pt clusters exhibit a remarkable stability under electrochemical...... - is observed. In light of the findings reported, developing highly-dispersed subnanometer Pt clusters as catalyst for PEMFCs is a realistic approach provided the operation conditions are suitably adjusted. Furthermore, mitigation strategies to improve the stability of few-atoms catalyst under electrochemical...

  9. Polarization Stability of Amorphous Piezoelectric Polyimides

    Science.gov (United States)

    Park, C.; Ounaies, Z.; Su, J.; Smith, J. G., Jr.; Harrison, J. S.

    2000-01-01

    Amorphous polyimides containing polar functional groups have been synthesized and investigated for potential use as high temperature piezoelectric sensors. The thermal stability of the piezoelectric effect of one polyimide was evaluated as a function of various curing and poling conditions under dynamic and static thermal stimuli. First, the polymer samples were thermally cycled under strain by systematically increasing the maximum temperature from 50 C to 200 C while the piezoelectric strain coefficient was being measured. Second, the samples were isothermally aged at an elevated temperature in air, and the isothermal decay of the remanent polarization was measured at room temperature as a function of time. Both conventional and corona poling methods were evaluated. This material exhibited good thermal stability of the piezoelectric properties up to 100 C.

  10. Smoothing effect for spatially distributed renewable resources and its impact on power grid robustness.

    Science.gov (United States)

    Nagata, Motoki; Hirata, Yoshito; Fujiwara, Naoya; Tanaka, Gouhei; Suzuki, Hideyuki; Aihara, Kazuyuki

    2017-03-01

    In this paper, we show that spatial correlation of renewable energy outputs greatly influences the robustness of the power grids against large fluctuations of the effective power. First, we evaluate the spatial correlation among renewable energy outputs. We find that the spatial correlation of renewable energy outputs depends on the locations, while the influence of the spatial correlation of renewable energy outputs on power grids is not well known. Thus, second, by employing the topology of the power grid in eastern Japan, we analyze the robustness of the power grid with spatial correlation of renewable energy outputs. The analysis is performed by using a realistic differential-algebraic equations model. The results show that the spatial correlation of the energy resources strongly degrades the robustness of the power grid. Our results suggest that we should consider the spatial correlation of the renewable energy outputs when estimating the stability of power grids.

  11. Radiation-assisted synthesis of Prussian blue nanoparticles using sugar as stabilizer

    International Nuclear Information System (INIS)

    Ling Chang; Shuquan Chang; Wei Han; Zheng Li; Zheng Zhang; Yaodong Dai; Haiqian Zhang

    2017-01-01

    Prussian blue (PB) nanoparticles were successfully synthesized via a γ radiation route in aqueous solutions using sugar as stabilizer at room temperature and ambient pressure. The particle size and shape can be affected by stabilizer and radiation conditions. When the stabilizer was sucrose and the radiation dose was 30 kGy, well-dispersed and uniform PB nanoparticles were obtained, which are 100-200 nm in diameter. They exhibit good ions exchange properties and have maximal Cs + adsorption capacity of 125.8 mg g -1 , which may be applied in radioactive wastewater treatments, ion battery etc. (author)

  12. Field Validation of the Stability Limit of a Multi MW Turbine

    Science.gov (United States)

    Kallesøe, Bjarne S.; Kragh, Knud A.

    2016-09-01

    Long slender blades of modern multi-megawatt turbines exhibit a flutter like instability at rotor speeds above a critical rotor speed. Knowing the critical rotor speed is crucial to a safe turbine design. The flutter like instability can only be estimated using geometrically non-linear aeroelastic codes. In this study, the estimated rotor speed stability limit of a 7 MW state of the art wind turbine is validated experimentally. The stability limit is estimated using Siemens Wind Powers in-house aeroelastic code, and the results show that the predicted stability limit is within 5% of the experimentally observed limit.

  13. Upcycling CERN Exhibitions

    CERN Multimedia

    Katarina Anthony

    2015-01-01

    Summer is coming - and with it, a new Microcosm exhibition showcasing CERN (see here). But while the new exhibit is preparing to enchant visitors, many have been asking about the site's former content. Will it simply be out with the old and in with the new? Not as such!   The plasma ball from Microcosm is now on display at the LHCb site. As Microcosm's new content is moving in, its old content is moving up. From LHCb to IdeaSquare, former Microcosm displays and objects are being installed across the CERN site. "Microcosm featured many elements that were well suited to life outside of the exhibition," says Emma Sanders, Microcosm project leader in the EDU group. "We didn't want this popular content to go to waste, and so set out to find them new homes across CERN." The LHCb experiment has received a number of Microcosm favourites, including the Rutherford experiment, the cosmic ray display and the Thomson experiment. "We&...

  14. Stabilized lasers for advanced gravitational wave detectors

    International Nuclear Information System (INIS)

    Willke, B; Danzmann, K; Kwee, P; Seifert, F; Frede, M; Kracht, D; Puncken, O; Schulz, B; Veltkamp, C; Wagner, S; Wessels, P; Winkelmann, L; King, P; Savage, R L Jr

    2008-01-01

    Second generation gravitational wave detectors require high power lasers with more than 100 W of output power and with very low temporal and spatial fluctuations. To achieve the demanding stability levels required, low noise techniques and adequate control actuators have to be part of the high power laser design. In addition feedback control and passive noise filtering is used to reduce the fluctuations in the so-called prestabilized laser system (PSL). In this paper, we discuss the design of a 200 W PSL which is under development for the Advanced LIGO gravitational wave detector and will present the first results. The PSL noise requirements for advanced gravitational wave detectors will be discussed in general and the stabilization scheme proposed for the Advanced LIGO PSL will be described

  15. Globe exhibit wins international acclaim

    CERN Multimedia

    Katarina Anthony

    2011-01-01

    The Globe’s “Universe of Particles” exhibition has recently received four prestigious awards for its avant-garde design. This external praise is great encouragement for the CERN exhibitions currently on the drawing board.   The Universe of Particles exhibition has won 4 awards for its avant-garde design. Back in 2008, the design company Atelier Brückner was presented with a challenge: to design the layout of a new permanent exhibition for CERN, one that would epitomize both the Organization and its research. The brief was concise but complex: the exhibit had to be symbolic of the Organization, use modern technology, engage and immerse visitors, and, preferably, use touch-screen technology. With the help of IArt, an interactive technology firm, and based on the content provided by CERN’s Education Group, Atelier Brückner developed the “Universe of Particles” exhibit as it is today. Its principal concept centred on the s...

  16. Spatial encoding in spinal sensorimotor circuits differs in different wild type mice strains

    Directory of Open Access Journals (Sweden)

    Schouenborg Jens

    2008-05-01

    Full Text Available Abstract Background Previous studies in the rat have shown that the spatial organisation of the receptive fields of nociceptive withdrawal reflex (NWR system are functionally adapted through experience dependent mechanisms, termed somatosensory imprinting, during postnatal development. Here we wanted to clarify 1 if mice exhibit a similar spatial encoding of sensory input to NWR as previously found in the rat and 2 if mice strains with a poor learning capacity in various behavioural tests, associated with deficient long term potention, also exhibit poor adaptation of NWR. The organisation of the NWR system in two adult wild type mouse strains with normal long term potentiation (LTP in hippocampus and two adult wild type mouse strains exhibiting deficiencies in corresponding LTP were used and compared to previous results in the rat. Receptive fields of reflexes in single hindlimb muscles were mapped with CO2 laser heat pulses. Results While the spatial organisation of the nociceptive receptive fields in mice with normal LTP were very similar to those in rats, the LTP impaired strains exhibited receptive fields of NWRs with aberrant sensitivity distributions. However, no difference was found in NWR thresholds or onset C-fibre latencies suggesting that the mechanisms determining general reflex sensitivity and somatosensory imprinting are different. Conclusion Our results thus confirm that sensory encoding in mice and rat NWR is similar, provided that mice strains with a good learning capability are studied and raise the possibility that LTP like mechanisms are involved in somatosensory imprinting.

  17. The effect of short-range spatial variability on soil sampling uncertainty

    Energy Technology Data Exchange (ETDEWEB)

    Perk, Marcel van der [Department of Physical Geography, Utrecht University, P.O. Box 80115, 3508 TC Utrecht (Netherlands)], E-mail: m.vanderperk@geo.uu.nl; De Zorzi, Paolo; Barbizzi, Sabrina; Belli, Maria [Agenzia per la Protezione dell' Ambiente e per i Servizi Tecnici (APAT), Servizio Laboratori, Misure ed Attivita di Campo, Via di Castel Romano, 100-00128 Roma (Italy); Fajgelj, Ales; Sansone, Umberto [International Atomic Energy Agency (IAEA), Agency' s Laboratories Seibersdorf, A-1400 Vienna (Austria); Jeran, Zvonka; Jacimovic, Radojko [Jozef Stefan Institute, Jamova 39, 1000 Ljubljana (Slovenia)

    2008-11-15

    This paper aims to quantify the soil sampling uncertainty arising from the short-range spatial variability of elemental concentrations in the topsoils of agricultural, semi-natural, and contaminated environments. For the agricultural site, the relative standard sampling uncertainty ranges between 1% and 5.5%. For the semi-natural area, the sampling uncertainties are 2-4 times larger than in the agricultural area. The contaminated site exhibited significant short-range spatial variability in elemental composition, which resulted in sampling uncertainties of 20-30%.

  18. The effect of short-range spatial variability on soil sampling uncertainty.

    Science.gov (United States)

    Van der Perk, Marcel; de Zorzi, Paolo; Barbizzi, Sabrina; Belli, Maria; Fajgelj, Ales; Sansone, Umberto; Jeran, Zvonka; Jaćimović, Radojko

    2008-11-01

    This paper aims to quantify the soil sampling uncertainty arising from the short-range spatial variability of elemental concentrations in the topsoils of agricultural, semi-natural, and contaminated environments. For the agricultural site, the relative standard sampling uncertainty ranges between 1% and 5.5%. For the semi-natural area, the sampling uncertainties are 2-4 times larger than in the agricultural area. The contaminated site exhibited significant short-range spatial variability in elemental composition, which resulted in sampling uncertainties of 20-30%.

  19. Professional mathematicians differ from controls in their spatial-numerical associations.

    Science.gov (United States)

    Cipora, Krzysztof; Hohol, Mateusz; Nuerk, Hans-Christoph; Willmes, Klaus; Brożek, Bartosz; Kucharzyk, Bartłomiej; Nęcka, Edward

    2016-07-01

    While mathematically impaired individuals have been shown to have deficits in all kinds of basic numerical representations, among them spatial-numerical associations, little is known about individuals with exceptionally high math expertise. They might have a more abstract magnitude representation or more flexible spatial associations, so that no automatic left/small and right/large spatial-numerical association is elicited. To pursue this question, we examined the Spatial Numerical Association of Response Codes (SNARC) effect in professional mathematicians which was compared to two control groups: Professionals who use advanced math in their work but are not mathematicians (mostly engineers), and matched controls. Contrarily to both control groups, Mathematicians did not reveal a SNARC effect. The group differences could not be accounted for by differences in mean response speed, response variance or intelligence or a general tendency not to show spatial-numerical associations. We propose that professional mathematicians possess more abstract and/or spatially very flexible numerical representations and therefore do not exhibit or do have a largely reduced default left-to-right spatial-numerical orientation as indexed by the SNARC effect, but we also discuss other possible accounts. We argue that this comparison with professional mathematicians also tells us about the nature of spatial-numerical associations in persons with much less mathematical expertise or knowledge.

  20. Effect of corner radius in stabilizing the low-Re flow past a cylinder

    KAUST Repository

    Zhang, Wei

    2017-08-03

    We perform global linear stability analysis on low-Re flow past an isolated cylinder with rounded corners. The objective of the present work is to investigate the effect of the cylinder geometry (corner radius) on the stability characteristics of the flow. Our investigation sheds light on new physics that the flow can be stabilized by partially rounding the cylinder in the critical and weakly super-critical flow regimes. The flow is first stabilized and then gradually destabilized as the cylinder varies from square to circular geometry. The sensitivity analysis reveals that the variation of stability is attributed to the different spatial variation trends of the backflow velocity in the near- and far-wake regions for various cylinder geometries. The results from the stability analysis are also verified with those of the direct simulations and very good agreement is achieved.

  1. Effect of corner radius in stabilizing the low-Re flow past a cylinder

    KAUST Repository

    Zhang, Wei; Samtaney, Ravindra

    2017-01-01

    We perform global linear stability analysis on low-Re flow past an isolated cylinder with rounded corners. The objective of the present work is to investigate the effect of the cylinder geometry (corner radius) on the stability characteristics of the flow. Our investigation sheds light on new physics that the flow can be stabilized by partially rounding the cylinder in the critical and weakly super-critical flow regimes. The flow is first stabilized and then gradually destabilized as the cylinder varies from square to circular geometry. The sensitivity analysis reveals that the variation of stability is attributed to the different spatial variation trends of the backflow velocity in the near- and far-wake regions for various cylinder geometries. The results from the stability analysis are also verified with those of the direct simulations and very good agreement is achieved.

  2. Hailstorm forecast from stability indexes in Southwestern France

    Science.gov (United States)

    Melcón, Pablo; Merino, Andrés; Sánchez, José Luis; Dessens, Jean; Gascón, Estíbaliz; Berthet, Claude; López, Laura; García-Ortega, Eduardo

    2016-04-01

    Forecasting hailstorms is a difficult task because of their small spatial and temporal scales. Over recent decades, stability indexes have been commonly used in operational forecasting to provide a simplified representation of different thermodynamic characteristics of the atmosphere, regarding the onset of convective events. However, they are estimated from vertical profiles obtained by radiosondes, which are usually available only twice a day and have limited spatial representativeness. Numerical models predictions can be used to overcome these drawbacks, providing vertical profiles with higher spatiotemporal resolution. The main objective of this study is to create a tool for hail prediction in the southwest of France, one of the European regions where hailstorms have a higher incidence. The Association Nationale d'Etude et de Lutte contre les Fleáux Atmosphériques (ANELFA) maintains there a dense hailpad network in continuous operation, which has created an extensive database of hail events, used in this study as ground truth. The new technique is aimed to classify the spatial distribution of different stability indexes on hail days. These indexes were calculated from vertical profiles at 1200 UTC provided by WRF numerical model, validated with radiosonde data from Bordeaux. Binary logistic regression is used to select those indexes that best represent thermodynamic conditions related to occurrence of hail in the zone. Then, they are combined in a single algorithm that surpassed the predictive power they have when used independently. Regression equation results in hail days are used in cluster analysis to identify different spatial patterns given by the probability algorithm. This new tool can be used in operational forecasting, in combination with synoptic and mesoscale techniques, to properly define hail probability and distribution. Acknowledgements The authors would like to thank the CEPA González Díez Foundation and the University of Leon for its

  3. Spatial complementarity of forests and farms: accounting for ecosystem services

    Science.gov (United States)

    Subhrendu K. Pattanayak; David T. Butry

    2006-01-01

    Our article considers the economic contributions of forest ecosystem services, using a case study from Flores, Indonesia, in which forest protection in upstream watersheds stabilize soil and hydrological flows in downstream farms. We focus on the demand for a weak complement to the ecosystem services--farm labor-- and account for spatial dependence due to economic...

  4. Spatial Working Memory Capacity Predicts Bias in Estimates of Location

    Science.gov (United States)

    Crawford, L. Elizabeth; Landy, David; Salthouse, Timothy A.

    2016-01-01

    Spatial memory research has attributed systematic bias in location estimates to a combination of a noisy memory trace with a prior structure that people impose on the space. Little is known about intraindividual stability and interindividual variation in these patterns of bias. In the current work, we align recent empirical and theoretical work on…

  5. Spatial EPR entanglement in atomic vapor quantum memory

    Science.gov (United States)

    Parniak, Michal; Dabrowski, Michal; Wasilewski, Wojciech

    Spatially-structured quantum states of light are staring to play a key role in modern quantum science with the rapid development of single-photon sensitive cameras. In particular, spatial degree of freedom holds a promise to enhance continous-variable quantum memories. Here we present the first demonstration of spatial entanglement between an atomic spin-wave and a photon measured with an I-sCMOS camera. The system is realized in a warm atomic vapor quantum memory based on rubidium atoms immersed in inert buffer gas. In the experiment we create and characterize a 12-dimensional entangled state exhibiting quantum correlations between a photon and an atomic ensemble in position and momentum bases. This state allows us to demonstrate the Einstein-Podolsky-Rosen paradox in its original version, with an unprecedented delay time of 6 μs between generation of entanglement and detection of the atomic state.

  6. Spatially balanced topological interaction grants optimal cohesion in flocking models.

    Science.gov (United States)

    Camperi, Marcelo; Cavagna, Andrea; Giardina, Irene; Parisi, Giorgio; Silvestri, Edmondo

    2012-12-06

    Models of self-propelled particles (SPPs) are an indispensable tool to investigate collective animal behaviour. Originally, SPP models were proposed with metric interactions, where each individual coordinates with neighbours within a fixed metric radius. However, recent experiments on bird flocks indicate that interactions are topological: each individual interacts with a fixed number of neighbours, irrespective of their distance. It has been argued that topological interactions are more robust than metric ones against external perturbations, a significant evolutionary advantage for systems under constant predatory pressure. Here, we test this hypothesis by comparing the stability of metric versus topological SPP models in three dimensions. We show that topological models are more stable than metric ones. We also show that a significantly better stability is achieved when neighbours are selected according to a spatially balanced topological rule, namely when interacting neighbours are evenly distributed in angle around the focal individual. Finally, we find that the minimal number of interacting neighbours needed to achieve fully stable cohesion in a spatially balanced model is compatible with the value observed in field experiments on starling flocks.

  7. Basin stability measure of different steady states in coupled oscillators

    Science.gov (United States)

    Rakshit, Sarbendu; Bera, Bidesh K.; Majhi, Soumen; Hens, Chittaranjan; Ghosh, Dibakar

    2017-04-01

    In this report, we investigate the stabilization of saddle fixed points in coupled oscillators where individual oscillators exhibit the saddle fixed points. The coupled oscillators may have two structurally different types of suppressed states, namely amplitude death and oscillation death. The stabilization of saddle equilibrium point refers to the amplitude death state where oscillations are ceased and all the oscillators converge to the single stable steady state via inverse pitchfork bifurcation. Due to multistability features of oscillation death states, linear stability theory fails to analyze the stability of such states analytically, so we quantify all the states by basin stability measurement which is an universal nonlocal nonlinear concept and it interplays with the volume of basins of attractions. We also observe multi-clustered oscillation death states in a random network and measure them using basin stability framework. To explore such phenomena we choose a network of coupled Duffing-Holmes and Lorenz oscillators which are interacting through mean-field coupling. We investigate how basin stability for different steady states depends on mean-field density and coupling strength. We also analytically derive stability conditions for different steady states and confirm by rigorous bifurcation analysis.

  8. Origin of Pareto-like spatial distributions in ecosystems.

    Science.gov (United States)

    Manor, Alon; Shnerb, Nadav M

    2008-12-31

    Recent studies of cluster distribution in various ecosystems revealed Pareto statistics for the size of spatial colonies. These results were supported by cellular automata simulations that yield robust criticality for endogenous pattern formation based on positive feedback. We show that this patch statistics is a manifestation of the law of proportionate effect. Mapping the stochastic model to a Markov birth-death process, the transition rates are shown to scale linearly with cluster size. This mapping provides a connection between patch statistics and the dynamics of the ecosystem; the "first passage time" for different colonies emerges as a powerful tool that discriminates between endogenous and exogenous clustering mechanisms. Imminent catastrophic shifts (such as desertification) manifest themselves in a drastic change of the stability properties of spatial colonies.

  9. Thermal stability and high temperature polymorphism of topochemically-prepared Dion–Jacobson triple-layered perovskites

    Energy Technology Data Exchange (ETDEWEB)

    Guertin, Stephen L.; Josepha, Elisha A.; Montasserasadi, Dariush; Wiley, John B., E-mail: jwiley@uno.edu

    2015-10-25

    The thermal stability of six Dion–Jacobson-related triple layered perovskites, ACa{sub 2}Nb{sub 3}O{sub 10} (A = H, NH{sub 4}, Li, Na, K, CuCl), was explored to 1000 °C. Each compound was produced topochemically by low-temperature (<500 °C) ion exchange from RbCa{sub 2}Nb{sub 3}O{sub 10}. The thermal behavior of the series was examined by variable temperature X-ray powder diffraction experiments in tandem with thermogravimetric analysis and differential scanning calorimetry. Five of the species were found to be low temperature/metastable phases, decomposing below 900 °C, where the stability of the series decreased with decreasing interlayer cation size. The compounds, A = Li, Na, K, exhibited high temperature polymorphism, with a completely reversible transition evident for KCa{sub 2}Nb{sub 3}O{sub 10}. - Highlights: • Thermal stability of topochemically prepared triple-layered perovskites studied. • Clear correlation seen between stability and identity of interlayer cation. • Several in ACa{sub 2}Nb{sub 3}O{sub 10} series (A = Li, Na, K) exhibit high temperature polymorphism.

  10. Stabilized Acoustic Levitation of Dense Materials Using a High-Powered Siren

    Science.gov (United States)

    Gammell, P. M.; Croonquist, A.; Wang, T. G.

    1982-01-01

    Stabilized acoustic levitation and manipulation of dense (e.g., steel) objects of 1 cm diameter, using a high powered siren, was demonstrated in trials that investigated the harmonic content and spatial distribution of the acoustic field, as well as the effect of sample position and reflector geometries on the acoustic field. Although further optimization is possible, the most stable operation achieved is expected to be adequate for most containerless processing applications. Best stability was obtained with an open reflector system, using a flat lower reflector and a slightly concave upper one. Operation slightly below resonance enhances stability as this minimizes the second harmonic, which is suspected of being a particularly destabilizing influence.

  11. The Spatial Politics of Spatial Representation

    DEFF Research Database (Denmark)

    Olesen, Kristian; Richardson, Tim

    2011-01-01

    spatial planning in Denmark reveals how fuzzy spatial representations and relational spatial concepts are being used to depoliticise strategic spatial planning processes and to camouflage spatial politics. The paper concludes that, while relational geography might play an important role in building......This paper explores the interplay between the spatial politics of new governance landscapes and innovations in the use of spatial representations in planning. The central premise is that planning experiments with new relational approaches become enmeshed in spatial politics. The case of strategic...

  12. M-Theory Model-Building and Proton Stability

    CERN Document Server

    Ellis, Jonathan Richard; Nanopoulos, Dimitri V; Ellis, John; Faraggi, Alon E.

    1998-01-01

    We study the problem of baryon stability in M theory, starting from realistic four-dimensional string models constructed using the free-fermion formulation of the weakly-coupled heterotic string. Suitable variants of these models manifest an enhanced custodial gauge symmetry that forbids to all orders the appearance of dangerous dimension-five baryon-decay operators. We exhibit the underlying geometric (bosonic) interpretation of these models, which have a $Z_2 \\times Z_2$ orbifold structure similar, but not identical, to the class of Calabi-Yau threefold compactifications of M and F theory investigated by Voisin and Borcea. A related generalization of their work may provide a solution to the problem of proton stability in M theory.

  13. M-theory model-building and proton stability

    International Nuclear Information System (INIS)

    Ellis, J.; Faraggi, A.E.; Nanopoulos, D.V.; Houston Advanced Research Center, The Woodlands, TX; Academy of Athens

    1997-09-01

    The authors study the problem of baryon stability in M theory, starting from realistic four-dimensional string models constructed using the free-fermion formulation of the weakly-coupled heterotic string. Suitable variants of these models manifest an enhanced custodial gauge symmetry that forbids to all orders the appearance of dangerous dimension-five baryon-decay operators. The authors exhibit the underlying geometric (bosonic) interpretation of these models, which have a Z 2 x Z 2 orbifold structure similar, but not identical, to the class of Calabi-Yau threefold compactifications of M and F theory investigated by Voisin and Borcea. A related generalization of their work may provide a solution to the problem of proton stability in M theory

  14. The effects of spatial autoregressive dependencies on inference in ordinary least squares: a geometric approach

    Science.gov (United States)

    Smith, Tony E.; Lee, Ka Lok

    2012-01-01

    There is a common belief that the presence of residual spatial autocorrelation in ordinary least squares (OLS) regression leads to inflated significance levels in beta coefficients and, in particular, inflated levels relative to the more efficient spatial error model (SEM). However, our simulations show that this is not always the case. Hence, the purpose of this paper is to examine this question from a geometric viewpoint. The key idea is to characterize the OLS test statistic in terms of angle cosines and examine the geometric implications of this characterization. Our first result is to show that if the explanatory variables in the regression exhibit no spatial autocorrelation, then the distribution of test statistics for individual beta coefficients in OLS is independent of any spatial autocorrelation in the error term. Hence, inferences about betas exhibit all the optimality properties of the classic uncorrelated error case. However, a second more important series of results show that if spatial autocorrelation is present in both the dependent and explanatory variables, then the conventional wisdom is correct. In particular, even when an explanatory variable is statistically independent of the dependent variable, such joint spatial dependencies tend to produce "spurious correlation" that results in over-rejection of the null hypothesis. The underlying geometric nature of this problem is clarified by illustrative examples. The paper concludes with a brief discussion of some possible remedies for this problem.

  15. Partial synchronization and spontaneous spatial ordering in coupled chaotic systems

    International Nuclear Information System (INIS)

    Ying Zhang; Gang Hu; Cerdeira, Hilda A.; Shigang Chen; Braun, Thomas; Yugui Yao

    2000-11-01

    A model of many symmetrically and locally coupled chaotic oscillators is studied. Partial chaotic synchronizations associated with spontaneous spatial ordering are demonstrated. Very rich patterns of the system are revealed, based on partial synchronization analysis. The stabilities of different partially synchronous spatiotemporal structures and some novel dynamical behaviors of these states are discussed both numerically and analytically. (author)

  16. Calculating the wind energy input to a system using a spatially explicit method that considers atmospheric stability

    Science.gov (United States)

    Atmospheric stability has a major effect in determining the wind energy doing work in the atmospheric boundary layer (ABL); however, it is seldom considered in determining this value in emergy analyses. One reason that atmospheric stability is not usually considered is that a sui...

  17. Stability of bumps in piecewise smooth neural fields with nonlinear adaptation

    KAUST Repository

    Kilpatrick, Zachary P.

    2010-06-01

    We study the linear stability of stationary bumps in piecewise smooth neural fields with local negative feedback in the form of synaptic depression or spike frequency adaptation. The continuum dynamics is described in terms of a nonlocal integrodifferential equation, in which the integral kernel represents the spatial distribution of synaptic weights between populations of neurons whose mean firing rate is taken to be a Heaviside function of local activity. Discontinuities in the adaptation variable associated with a bump solution means that bump stability cannot be analyzed by constructing the Evans function for a network with a sigmoidal gain function and then taking the high-gain limit. In the case of synaptic depression, we show that linear stability can be formulated in terms of solutions to a system of pseudo-linear equations. We thus establish that sufficiently strong synaptic depression can destabilize a bump that is stable in the absence of depression. These instabilities are dominated by shift perturbations that evolve into traveling pulses. In the case of spike frequency adaptation, we show that for a wide class of perturbations the activity and adaptation variables decouple in the linear regime, thus allowing us to explicitly determine stability in terms of the spectrum of a smooth linear operator. We find that bumps are always unstable with respect to this class of perturbations, and destabilization of a bump can result in either a traveling pulse or a spatially localized breather. © 2010 Elsevier B.V. All rights reserved.

  18. Hummingbirds control hovering flight by stabilizing visual motion.

    Science.gov (United States)

    Goller, Benjamin; Altshuler, Douglas L

    2014-12-23

    Relatively little is known about how sensory information is used for controlling flight in birds. A powerful method is to immerse an animal in a dynamic virtual reality environment to examine behavioral responses. Here, we investigated the role of vision during free-flight hovering in hummingbirds to determine how optic flow--image movement across the retina--is used to control body position. We filmed hummingbirds hovering in front of a projection screen with the prediction that projecting moving patterns would disrupt hovering stability but stationary patterns would allow the hummingbird to stabilize position. When hovering in the presence of moving gratings and spirals, hummingbirds lost positional stability and responded to the specific orientation of the moving visual stimulus. There was no loss of stability with stationary versions of the same stimulus patterns. When exposed to a single stimulus many times or to a weakened stimulus that combined a moving spiral with a stationary checkerboard, the response to looming motion declined. However, even minimal visual motion was sufficient to cause a loss of positional stability despite prominent stationary features. Collectively, these experiments demonstrate that hummingbirds control hovering position by stabilizing motions in their visual field. The high sensitivity and persistence of this disruptive response is surprising, given that the hummingbird brain is highly specialized for sensory processing and spatial mapping, providing other potential mechanisms for controlling position.

  19. Sports training enhances visuo-spatial cognition regardless of open-closed typology

    Directory of Open Access Journals (Sweden)

    Ting-Yu Chueh

    2017-05-01

    Full Text Available The aim of this study was to investigate the effects of open and closed sport participation on visuo-spatial attention and memory performance among young adults. Forty-eight young adults—16 open-skill athletes, 16 closed-skill athletes, and 16 non-athletes controls—were recruited for the study. Both behavioral performance and event-related potential (ERP measurement were assessed when participants performed non-delayed and delayed match-to-sample task that tested visuo-spatial attention and memory processing. Results demonstrated that regardless of training typology, the athlete groups exhibited shorter reaction times in both the visuo-spatial attention and memory conditions than the control group with no existence of speed-accuracy trade-off. Similarly, a larger P3 amplitudes were observed in both athlete groups than in the control group for the visuo-spatial memory condition. These findings suggest that sports training, regardless of typology, are associated with superior visuo-spatial attention and memory performance, and more efficient neural resource allocation in memory processing.

  20. Demonstration of Hadoop-GIS: A Spatial Data Warehousing System Over MapReduce.

    Science.gov (United States)

    Aji, Ablimit; Sun, Xiling; Vo, Hoang; Liu, Qioaling; Lee, Rubao; Zhang, Xiaodong; Saltz, Joel; Wang, Fusheng

    2013-11-01

    The proliferation of GPS-enabled devices, and the rapid improvement of scientific instruments have resulted in massive amounts of spatial data in the last decade. Support of high performance spatial queries on large volumes data has become increasingly important in numerous fields, which requires a scalable and efficient spatial data warehousing solution as existing approaches exhibit scalability limitations and efficiency bottlenecks for large scale spatial applications. In this demonstration, we present Hadoop-GIS - a scalable and high performance spatial query system over MapReduce. Hadoop-GIS provides an efficient spatial query engine to process spatial queries, data and space based partitioning, and query pipelines that parallelize queries implicitly on MapReduce. Hadoop-GIS also provides an expressive, SQL-like spatial query language for workload specification. We will demonstrate how spatial queries are expressed in spatially extended SQL queries, and submitted through a command line/web interface for execution. Parallel to our system demonstration, we explain the system architecture and details on how queries are translated to MapReduce operators, optimized, and executed on Hadoop. In addition, we will showcase how the system can be used to support two representative real world use cases: large scale pathology analytical imaging, and geo-spatial data warehousing.

  1. Micropore Structure of Cement-Stabilized Gold Mine Tailings

    Directory of Open Access Journals (Sweden)

    Joon Kyu Lee

    2018-03-01

    Full Text Available Mine tailings have often to be stabilized by mixing them with cementing agents. In this study, the pore structure of gold tailings stabilized with Portland cement was evaluated by means of mercury intrusion porosimetry. The investigation was conducted on samples prepared with different fractions of tailings and cement as well as on samples activated with elevated temperature curing and chemical (CaCl2 addition. It was observed that all mixed samples exhibit a mono-modal pore size distribution, indicating that the cement-stabilized tailings are characterized by a single-porosity structure. The results also showed that the higher fraction of tailings and cement leads to a dense and finer pore structure. The total porosity of mixture samples decreases with increasing curing temperature and CaCl2 concentration due to the acceleration of hydration reaction.

  2. [Stabilization of Cadmium Contaminated Soils by Ferric Ion Modified Attapulgite (Fe/ATP)--Characterizations and Stabilization Mechanism].

    Science.gov (United States)

    Rong, Yang; Li, Rong-bo; Zhou, Yong-li; Chen, Jing; Wang, Lin-ling; Lu, Xiao-hua

    2015-08-01

    Ferric ion modified attapulgite (Fe/ATP) was prepared by impregnation and its structure and morphology were characterized. The toxicity characteristic leaching procedure (TCLP) was used to evaluate the effect of Cadmium( Cd) stabilization in soil with the addition of attapulgite (ATP) and Fe/ATP. The stabilization mechanism of Cd was further elucidated by comparing the morphologies and structure of ATP and Fe/ATP before and after Cd adsorption. Fe/ATP exhibited much better adsorption capacity than ATP, suggesting different adsorption mechanisms occurred between ATP and Fe/ATP. The leaching concentrations of Cd in soil decreased by 45% and 91% respectively, with the addition of wt. 20% ATP and Fe/ATP. The former was attributed to the interaction between Cd2 and --OH groups by chemical binding to form inner-sphere complexes in ATP and the attachment between Cd2+ and the defect sites in ATP framework. Whereas Cd stabilization with Fe/ATP was resulted from the fact that the active centers (--OH bonds or O- sites) on ATP could react with Fe3+ giving Fe--O--Cd-- bridges, which helped stabilize Cd in surface soil. What'more, the ferric oxides and metal hydroxides on the surface of ATP could interact with Cd, probably by the formation of cadmium ferrite. In conclusion, Fe/ATP, which can be easily prepared, holds promise as a potential low-cost and environmental friendly stabilizing agent for remediation of soil contaminated with heavy metals.

  3. Spatially localized, temporally quasiperiodic, discrete nonlinear excitations

    International Nuclear Information System (INIS)

    Cai, D.; Bishop, A.R.; Gronbech-Jensen, N.

    1995-01-01

    In contrast to the commonly discussed discrete breather, which is a spatially localized, time-periodic solution, we present an exact solution of a discrete nonlinear Schroedinger breather which is a spatially localized, temporally quasiperiodic nonlinear coherent excitation. This breather is a multiple-soliton solution in the sense of the inverse scattering transform. A discrete breather of multiple frequencies is conceptually important in studies of nonlinear lattice systems. We point out that, for this breather, the incommensurability of its frequencies is a discrete lattice effect and these frequencies become commensurate in the continuum limit. To understand the dynamical properties of the breather, we also discuss its stability and its behavior in the presence of an external potential. Finally, we indicate how to obtain an exact N-soliton breather as a discrete generalization of the continuum multiple-soliton solution

  4. Arctic Submarine Slope Stability

    Science.gov (United States)

    Winkelmann, D.; Geissler, W.

    2010-12-01

    Submarine landsliding represents aside submarine earthquakes major natural hazard to coastal and sea-floor infrastructure as well as to coastal communities due to their ability to generate large-scale tsunamis with their socio-economic consequences. The investigation of submarine landslides, their conditions and trigger mechanisms, recurrence rates and potential impact remains an important task for the evaluation of risks in coastal management and offshore industrial activities. In the light of a changing globe with warming oceans and rising sea-level accompanied by increasing human population along coasts and enhanced near- and offshore activities, slope stability issues gain more importance than ever before. The Arctic exhibits the most rapid and drastic changes and is predicted to change even faster. Aside rising air temperatures, enhanced inflow of less cooled Atlantic water into the Arctic Ocean reduces sea-ice cover and warms the surroundings. Slope stability is challenged considering large areas of permafrost and hydrates. The Hinlopen/Yermak Megaslide (HYM) north of Svalbard is the first and so far only reported large-scale submarine landslide in the Arctic Ocean. The HYM exhibits the highest headwalls that have been found on siliciclastic margins. With more than 10.000 square kilometer areal extent and app. 2.400 cubic kilometer of involved sedimentary material, it is one of the largest exposed submarine slides worldwide. Geometry and age put this slide in a special position in discussing submarine slope stability on glaciated continental margins. The HYM occurred 30 ka ago, when the global sea-level dropped by app. 50 m within less than one millennium due to rapid onset of global glaciation. It probably caused a tsunami with circum-Arctic impact and wave heights exceeding 130 meters. The HYM affected the slope stability field in its neighbourhood by removal of support. Post-megaslide slope instability as expressed in creeping and smaller-scaled slides are

  5. Sensing disks for slug-type calorimeters have higher temperature stability

    Science.gov (United States)

    1967-01-01

    Graphite sensing disk for slug-type radiation calorimeters exhibits better performance at high temperatures than copper and nickel disks. The graphite is heat-soaked to stabilize its emittance and the thermocouple is protected from the graphite so repeated temperature cycling does not change its sensitivity.

  6. Non-monotonic resonance in a spatially forced Lengyel-Epstein model

    Energy Technology Data Exchange (ETDEWEB)

    Haim, Lev [Physics Department, Ben-Gurion University of the Negev, Beer-Sheva 84105 (Israel); Department of Oncology, Soroka University Medical Center, Beer-Sheva 84101 (Israel); Hagberg, Aric [Center for Nonlinear Studies, Theoretical Division, Los Alamos National Laboratory, Los Alamos, New Mexico 87545 (United States); Meron, Ehud [Physics Department, Ben-Gurion University of the Negev, Beer-Sheva 84105 (Israel); Department of Solar Energy and Environmental Physics, BIDR, Ben-Gurion University of the Negev, Sede Boqer Campus, Midreshet Ben-Gurion 84990 (Israel)

    2015-06-15

    We study resonant spatially periodic solutions of the Lengyel-Epstein model modified to describe the chlorine dioxide-iodine-malonic acid reaction under spatially periodic illumination. Using multiple-scale analysis and numerical simulations, we obtain the stability ranges of 2:1 resonant solutions, i.e., solutions with wavenumbers that are exactly half of the forcing wavenumber. We show that the width of resonant wavenumber response is a non-monotonic function of the forcing strength, and diminishes to zero at sufficiently strong forcing. We further show that strong forcing may result in a π/2 phase shift of the resonant solutions, and argue that the nonequilibrium Ising-Bloch front bifurcation can be reversed. We attribute these behaviors to an inherent property of forcing by periodic illumination, namely, the increase of the mean spatial illumination as the forcing amplitude is increased.

  7. Greenhouse Earth: A Traveling Exhibition

    International Nuclear Information System (INIS)

    Booth, W.H.; Caesar, S.

    1992-09-01

    The Franklin Institute Science Museum provided an exhibit entitled the Greenhouse Earth: A Traveling Exhibition. This 3500 square-foot exhibit on global climate change was developed in collaboration with the Association of Science-Technology Centers. The exhibit opened at The Franklin Institute on February 14, 1992, welcoming 291,000 visitors over its three-month stay. During its three-year tour, Greenhouse Earth will travel to ten US cities, reaching two million visitors. Greenhouse Earth aims to deepen public understanding of the scientific issues of global warming and the conservation measures that can be taken to slow its effects. The exhibit features hands-on exhibitry, interactive computer programs and videos, a theater production, a ''demonstration cart,'' guided tours, and lectures. supplemental educational programs at the Institute included a teachers preview, a symposium on climate change, and a ''satellite field trip.'' The development of Greenhouse Earth included front-end and formative evaluation procedures. Evaluation includes interviews with visitors, prototypes, and summative surveys for participating museums. During its stay in Philadelphia, Greenhouse Earth was covered by the local and national press, with reviews in print and broadcast media. Greenhouse Earth is the first large-scale museum exhibit to address global climate change

  8. Concurrent temporal stability of the apparent electrical conductivity and soil water content

    Science.gov (United States)

    Knowledge of spatio-temporal soil water content (SWC) variability within agricultural fields is useful to improve crop management. Spatial patterns of soil water contents can be characterized using the temporal stability analysis, however high density sampling is required. Soil apparent electrical c...

  9. Temporal and spatial distribution characteristics in the natural plague foci of Chinese Mongolian gerbils based on spatial autocorrelation.

    Science.gov (United States)

    Du, Hai-Wen; Wang, Yong; Zhuang, Da-Fang; Jiang, Xiao-San

    2017-08-07

    The nest flea index of Meriones unguiculatus is a critical indicator for the prevention and control of plague, which can be used not only to detect the spatial and temporal distributions of Meriones unguiculatus, but also to reveal its cluster rule. This research detected the temporal and spatial distribution characteristics of the plague natural foci of Mongolian gerbils by body flea index from 2005 to 2014, in order to predict plague outbreaks. Global spatial autocorrelation was used to describe the entire spatial distribution pattern of the body flea index in the natural plague foci of typical Chinese Mongolian gerbils. Cluster and outlier analysis and hot spot analysis were also used to detect the intensity of clusters based on geographic information system methods. The quantity of M. unguiculatus nest fleas in the sentinel surveillance sites from 2005 to 2014 and host density data of the study area from 2005 to 2010 used in this study were provided by Chinese Center for Disease Control and Prevention. The epidemic focus regions of the Mongolian gerbils remain the same as the hot spot regions relating to the body flea index. High clustering areas possess a similar pattern as the distribution pattern of the body flea index indicating that the transmission risk of plague is relatively high. In terms of time series, the area of the epidemic focus gradually increased from 2005 to 2007, declined rapidly in 2008 and 2009, and then decreased slowly and began trending towards stability from 2009 to 2014. For the spatial change, the epidemic focus regions began moving northward from the southwest epidemic focus of the Mongolian gerbils from 2005 to 2007, and then moved from north to south in 2007 and 2008. The body flea index of Chinese gerbil foci reveals significant spatial and temporal aggregation characteristics through the employing of spatial autocorrelation. The diversity of temporary and spatial distribution is mainly affected by seasonal variation, the human

  10. Axisymmetric annular curtain stability

    International Nuclear Information System (INIS)

    Ahmed, Zahir U; Khayat, Roger E; Maissa, Philippe; Mathis, Christian

    2012-01-01

    A temporal stability analysis was carried out to investigate the stability of an axially moving viscous annular liquid jet subject to axisymmetric disturbances in surrounding co-flowing viscous gas media. We investigated in this study the effects of inertia, surface tension, the gas-to-liquid density ratio, the inner-to-outer radius ratio and the gas-to-liquid viscosity ratio on the stability of the jet. With an increase in inertia, the growth rate of the unstable disturbances is found to increase. The dominant (or most unstable) wavenumber decreases with increasing Reynolds number for larger values of the gas-to-liquid viscosity ratio. However, an opposite tendency for the most unstable wavenumber is predicted for small viscosity ratio in the same inertia range. The surrounding gas density, in the presence of viscosity, always reduces the growth rate, hence stabilizing the flow. There exists a critical value of the density ratio above which the flow becomes stable for very small viscosity ratio, whereas for large viscosity ratio, no stable flow appears in the same range of the density ratio. The curvature has a significant destabilizing effect on the thin annular jet, whereas for a relatively thick jet, the maximum growth rate decreases as the inner radius increases, irrespective of the surrounding gas viscosity. The degree of instability increases with Weber number for a relatively large viscosity ratio. In contrast, for small viscosity ratio, the growth rate exhibits a dramatic dependence on the surface tension. There is a small Weber number range, which depends on the viscosity ratio, where the flow is stable. The viscosity ratio always stabilizes the flow. However, the dominant wavenumber increases with increasing viscosity ratio. The range of unstable wavenumbers is affected only by the curvature effect. (paper)

  11. Two-group Analysis of Xenon Stability in Slab Geometry by Modal Expansion

    International Nuclear Information System (INIS)

    Norinder, O.

    1963-05-01

    Xenon spatial stability is analyzed with the flux represented by two neutron energy groups. General formulas are given for expansions in a system of modes. Detailed formulas are recorded for a slab described by sinusoidal modes. A short description is given of a Mercury Autocode program for numerical calculations in slab geometry. The essential input parameters and results are noted for 80 computed cases. The main body of the calculations were intended to clarify the xenon stability properties of the Marviken reactor, which was found to have a sufficient margin against unstable xenon oscillations. The neutron flux detection and the control rod insertion in the slab were found to have a large influence on the stability in spite of the nonexistence of space-selective control in the systems investigated. Very good agreement was found between stability limits calculated according to Randall and St. John and stability limits calculated by the program

  12. Two-group Analysis of Xenon Stability in Slab Geometry by Modal Expansion

    Energy Technology Data Exchange (ETDEWEB)

    Norinder, O

    1963-05-15

    Xenon spatial stability is analyzed with the flux represented by two neutron energy groups. General formulas are given for expansions in a system of modes. Detailed formulas are recorded for a slab described by sinusoidal modes. A short description is given of a Mercury Autocode program for numerical calculations in slab geometry. The essential input parameters and results are noted for 80 computed cases. The main body of the calculations were intended to clarify the xenon stability properties of the Marviken reactor, which was found to have a sufficient margin against unstable xenon oscillations. The neutron flux detection and the control rod insertion in the slab were found to have a large influence on the stability in spite of the nonexistence of space-selective control in the systems investigated. Very good agreement was found between stability limits calculated according to Randall and St. John and stability limits calculated by the program.

  13. Molecular mechanisms for the destabilization and restabilization of reactivated spatial memory in the Morris water maze

    Directory of Open Access Journals (Sweden)

    Kim Ryang

    2011-02-01

    Full Text Available Abstract Background Memory retrieval is not a passive process. Recent studies have shown that reactivated memory is destabilized and then restabilized through gene expression-dependent reconsolidation. Molecular studies on the regulation of memory stability after retrieval have focused almost exclusively on fear memory, especially on the restabilization process of the reactivated fear memory. We previously showed that, similarly with fear memories, reactivated spatial memory undergoes reconsolidation in the Morris water maze. However, the underlying molecular mechanisms by which reactivated spatial memory is destabilized and restabilized remain poorly understood. In this study, we investigated the molecular mechanism that regulates the stability of the reactivated spatial memory. Results We first showed that pharmacological inactivation of the N-methyl-D-aspartate glutamate receptor (NMDAR in the hippocampus or genetic inhibition of cAMP-responsible element binding protein (CREB-mediated transcription disrupted reactivated spatial memory. Finally, we showed that pharmacological inhibition of cannabinoid receptor 1 (CB1 and L-type voltage gated calcium channels (LVGCCs in the hippocampus blocked the disruption of the reactivated spatial memory by the inhibition of protein synthesis. Conclusions Our findings indicated that the reactivated spatial memory is destabilized through the activation of CB1 and LVGCCs and then restabilized through the activation of NMDAR- and CREB-mediated transcription. We also suggest that the reactivated spatial memory undergoes destabilization and restabilization in the hippocampus, through similar molecular processes as those for reactivated contextual fear memories, which require CB1 and LVGCCs for destabilization and NMDAR and CREB for restabilization.

  14. Effect of preparation methods on dispersion stability and electrochemical performance of graphene sheets

    International Nuclear Information System (INIS)

    Chen, Li; Li, Na; Zhang, Mingxia; Li, Pinnan; Lin, Zhengping

    2017-01-01

    Chemical exfoliation is one of the most important strategies for preparing graphene. The aggregation of graphene sheets severely prevents graphene from exhibiting excellent properties. However, there are no attempts to investigate the effect of preparation methods on the dispersity of graphene sheets. In this study, three chemical exfoliation methods, including Hummers method, modified Hummers method, and improved method, were used to prepare graphene sheets. The influence of preparation methods on the structure, dispersion stability in organic solvents, and electrochemical properties of graphene sheets were investigated. Fourier transform infrared microscopy, Raman spectra, transmission electron microscopy, and UV–vis spectrophotometry were employed to analyze the structure of the as-prepared graphene sheets. The results showed that graphene prepared by improved method exhibits excellent dispersity and stability in organic solvents without any additional stabilizer or modifier, which is attributed to the completely exfoliation and regular structure. Moreover, cyclic voltammetric and electrochemical impedance spectroscopy measurements showed that graphene prepared by improved method exhibits superior electrochemical properties than that prepared by the other two methods. - Graphical abstract: Graphene oxides with different oxidation degree were obtained via three methods, and then graphene with different crystal structures were created by chemical reduction of exfoliated graphene oxides. - Highlights: • Graphene oxides with different oxidation degree were obtained via three oxidation methods. • The influence of oxidation methods on microstructure of graphene was investigated. • The effect of oxidation methods on dispersion stability of graphene was investigated. • The effect of oxidation methods on electrochemical properties of graphene was discussed.

  15. Effect of preparation methods on dispersion stability and electrochemical performance of graphene sheets

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Li, E-mail: chenli1981@lut.cn; Li, Na; Zhang, Mingxia; Li, Pinnan; Lin, Zhengping

    2017-05-15

    Chemical exfoliation is one of the most important strategies for preparing graphene. The aggregation of graphene sheets severely prevents graphene from exhibiting excellent properties. However, there are no attempts to investigate the effect of preparation methods on the dispersity of graphene sheets. In this study, three chemical exfoliation methods, including Hummers method, modified Hummers method, and improved method, were used to prepare graphene sheets. The influence of preparation methods on the structure, dispersion stability in organic solvents, and electrochemical properties of graphene sheets were investigated. Fourier transform infrared microscopy, Raman spectra, transmission electron microscopy, and UV–vis spectrophotometry were employed to analyze the structure of the as-prepared graphene sheets. The results showed that graphene prepared by improved method exhibits excellent dispersity and stability in organic solvents without any additional stabilizer or modifier, which is attributed to the completely exfoliation and regular structure. Moreover, cyclic voltammetric and electrochemical impedance spectroscopy measurements showed that graphene prepared by improved method exhibits superior electrochemical properties than that prepared by the other two methods. - Graphical abstract: Graphene oxides with different oxidation degree were obtained via three methods, and then graphene with different crystal structures were created by chemical reduction of exfoliated graphene oxides. - Highlights: • Graphene oxides with different oxidation degree were obtained via three oxidation methods. • The influence of oxidation methods on microstructure of graphene was investigated. • The effect of oxidation methods on dispersion stability of graphene was investigated. • The effect of oxidation methods on electrochemical properties of graphene was discussed.

  16. Protection enhances community and habitat stability: evidence from a mediterranean marine protected area.

    Science.gov (United States)

    Fraschetti, Simonetta; Guarnieri, Giuseppe; Bevilacqua, Stanislao; Terlizzi, Antonio; Boero, Ferdinando

    2013-01-01

    Rare evidences support that Marine Protected Areas (MPAs) enhance the stability of marine habitats and assemblages. Based on nine years of observation (2001-2009) inside and outside a well managed MPA, we assessed the potential of conservation and management actions to modify patterns of spatial and/or temporal variability of Posidonia oceanica meadows, the lower midlittoral and the shallow infralittoral rock assemblages. Significant differences in both temporal variations and spatial patterns were observed between protected and unprotected locations. A lower temporal variability in the protected vs. unprotected assemblages was found in the shallow infralittoral, demonstrating that, at least at local scale, protection can enhance community stability. Macrobenthos with long-lived and relatively slow-growing invertebrates and structurally complex algal forms were homogeneously distributed in space and went through little fluctuations in time. In contrast, a mosaic of disturbed patches featured unprotected locations, with small-scale shifts from macroalgal stands to barrens, and harsh temporal variations between the two states. Opposite patterns of spatial and temporal variability were found for the midlittoral assemblages. Despite an overall clear pattern of seagrass regression through time, protected meadows showed a significantly higher shoot density than unprotected ones, suggesting a higher resistance to local human activities. Our results support the assumption that the exclusion/management of human activities within MPAs enhance the stability of the structural components of protected marine systems, reverting or arresting threat-induced trajectories of change.

  17. The Problem of the Instrument Stabilization During Hydrographic Measurements

    Directory of Open Access Journals (Sweden)

    Felski Andrzej

    2016-06-01

    Full Text Available Performing any measurement on watercraft is connected with many additional difficulties caused by the sea-environment. The most important is the problem of spatial stabilization of measurement systems, which are usually fastened to craft body. As soon as usually these measurement are executed during the move of the craft additional question is the accuracy of execution the planed trajectory.

  18. The potential of diffraction grating for spatial applications

    Science.gov (United States)

    Jourlin, Y.; Parriaux, O.; Pigeon, F.; Tischenko, A. V.

    2017-11-01

    Diffraction gratings are know, and have been fabricated for more than one century. They are now making a come back for two reasons: first, because they are now better understood which leads to the efficient exploitation of what was then called their "anomalies"; secondly, because they are now fabricable by means of the modern manufacturing potential of planar technologies. Novel grating can now perform better than conventional gratings, and address new application fields which were not expected to be theirs. This is the case of spatial applications where they can offer multiple optical functions, low size, low weight and mechanical robustness. The proposed contribution will briefly discuss the use of gratings for spatial applications. One of the most important applications is in the measurement of displacement. Usual translation and rotation sensors are bulky devices, which impose a system breakdown leading to cumbersome and heavy assemblies. We are proposing a miniaturized version of the traditional moving grating technique using submicron gratings and a specific OptoASIC which enables the measurement function to be non-obtrusively inserted into light and compact electro-mechanical systems. Nanometer resolution is possible with no compromise on the length of the measurement range. Another family of spatial application is in the field of spectrometers where new grating types allow a more flexible processing of the optical spectrum. Another family of applications addresses the question of inter-satellite communications: the introduction of gratings in laser cavities or in the laser mirrors enables the stabilization of the emitted polarization, the stabilization of the frequency as well as wide range frequency sweeping without mobile parts.

  19. Conditional stability and uniqueness for determining two coefficients in a hyperbolic–parabolic system

    International Nuclear Information System (INIS)

    Wu, Bin; Liu, Jijun

    2011-01-01

    We study the inverse problem of determining two spatially varying coefficients in a thermoelastic model with the following observation data: displacement in a subdomain ω satisfying ∂ω superset of ∂Ω along a sufficiently large time interval, both displacement and temperature at a suitable time over the whole spatial domain. Based on a Carleman estimate on the hyperbolic–parabolic system, we prove the Lipschitz stability and the uniqueness for this inverse problem under some a priori information

  20. On the Linear Stability of the Fifth-Order WENO Discretization

    KAUST Repository

    Motamed, Mohammad

    2010-10-03

    We study the linear stability of the fifth-order Weighted Essentially Non-Oscillatory spatial discretization (WENO5) combined with explicit time stepping applied to the one-dimensional advection equation. We show that it is not necessary for the stability domain of the time integrator to include a part of the imaginary axis. In particular, we show that the combination of WENO5 with either the forward Euler method or a two-stage, second-order Runge-Kutta method is linearly stable provided very small time step-sizes are taken. We also consider fifth-order multistep time discretizations whose stability domains do not include the imaginary axis. These are found to be linearly stable with moderate time steps when combined with WENO5. In particular, the fifth-order extrapolated BDF scheme gave superior results in practice to high-order Runge-Kutta methods whose stability domain includes the imaginary axis. Numerical tests are presented which confirm the analysis. © Springer Science+Business Media, LLC 2010.

  1. Exhibition

    CERN Multimedia

    Staff Association

    2016-01-01

    Encounters Hanne Blitz From February 1st to 12th 2016 CERN Meyrin, Main Building What is our reaction to a first encounter with a tourist attraction? Contemporary Dutch painter Hanne Blitz captures visitors' responses to art and architecture, sweeping vistas and symbolic memorials. Encounters, a series of oil paintings curated specially for this CERN exhibition, depicts tourists visiting cultural highlights around the world. A thought-provoking journey not to be missed, and a tip of the hat to CERN's large Hadron Collider.

  2. Sonic morphology: Aesthetic dimensional auditory spatial awareness

    Science.gov (United States)

    Whitehouse, Martha M.

    The sound and ceramic sculpture installation, " Skirting the Edge: Experiences in Sound & Form," is an integration of art and science demonstrating the concept of sonic morphology. "Sonic morphology" is herein defined as aesthetic three-dimensional auditory spatial awareness. The exhibition explicates my empirical phenomenal observations that sound has a three-dimensional form. Composed of ceramic sculptures that allude to different social and physical situations, coupled with sound compositions that enhance and create a three-dimensional auditory and visual aesthetic experience (see accompanying DVD), the exhibition supports the research question, "What is the relationship between sound and form?" Precisely how people aurally experience three-dimensional space involves an integration of spatial properties, auditory perception, individual history, and cultural mores. People also utilize environmental sound events as a guide in social situations and in remembering their personal history, as well as a guide in moving through space. Aesthetically, sound affects the fascination, meaning, and attention one has within a particular space. Sonic morphology brings art forms such as a movie, video, sound composition, and musical performance into the cognitive scope by generating meaning from the link between the visual and auditory senses. This research examined sonic morphology as an extension of musique concrete, sound as object, originating in Pierre Schaeffer's work in the 1940s. Pointing, as John Cage did, to the corporeal three-dimensional experience of "all sound," I composed works that took their total form only through the perceiver-participant's participation in the exhibition. While contemporary artist Alvin Lucier creates artworks that draw attention to making sound visible, "Skirting the Edge" engages the perceiver-participant visually and aurally, leading to recognition of sonic morphology.

  3. Stabilizing canonical-ensemble calculations in the auxiliary-field Monte Carlo method

    Science.gov (United States)

    Gilbreth, C. N.; Alhassid, Y.

    2015-03-01

    Quantum Monte Carlo methods are powerful techniques for studying strongly interacting Fermi systems. However, implementing these methods on computers with finite-precision arithmetic requires careful attention to numerical stability. In the auxiliary-field Monte Carlo (AFMC) method, low-temperature or large-model-space calculations require numerically stabilized matrix multiplication. When adapting methods used in the grand-canonical ensemble to the canonical ensemble of fixed particle number, the numerical stabilization increases the number of required floating-point operations for computing observables by a factor of the size of the single-particle model space, and thus can greatly limit the systems that can be studied. We describe an improved method for stabilizing canonical-ensemble calculations in AFMC that exhibits better scaling, and present numerical tests that demonstrate the accuracy and improved performance of the method.

  4. Violation of Bell's inequality with continuous spatial variables

    International Nuclear Information System (INIS)

    Abouraddy, Ayman F.; Yarnall, Timothy; Saleh, Bahaa E. A.; Teich, Malvin C.

    2007-01-01

    The Einstein-Podolsky-Rosen (EPR) argument revealed the paradoxical properties of a two-particle system entangled continuously in the spatial parameter. Yet a direct test of quantum nonlocality exhibited by this state, via a violation of Bell's inequality, has not been forthcoming. In this paper, we identify and construct experimental arrangements comprising simple optical components, without nonlinearities or moving parts, that implement operators in the spatial-parity space of single-photon fields that correspond to the familiar Pauli spin operators. We achieve this by first establishing an isomorphism between the single-mode multiphoton electromagnetic-field space spanned by a Fock-state basis and the single-photon multimode electromagnetic-field space spanned by a spatial-eigenmode basis. We then proceed to construct a Hilbert space with a two-dimensional basis of spatial even-odd parity modes. In particular, we describe an arrangement that implements a rotation in the parity space of each photon of an entangled-photon pair, allowing for a straightforward experimental test of Bell's inequality using the EPR state. Finally, the violation of a Bell inequality is quantified in terms of the physical parameters of the two-photon source

  5. SHARP: A Spatially Higher-order, Relativistic Particle-in-cell Code

    Energy Technology Data Exchange (ETDEWEB)

    Shalaby, Mohamad; Broderick, Avery E. [Department of Physics and Astronomy, University of Waterloo, 200 University Avenue West, Waterloo, ON, N2L 3G1 (Canada); Chang, Philip [Department of Physics, University of Wisconsin-Milwaukee, 1900 E. Kenwood Boulevard, Milwaukee, WI 53211 (United States); Pfrommer, Christoph [Leibniz-Institut für Astrophysik Potsdam (AIP), An der Sternwarte 16, D-14482 Potsdam (Germany); Lamberts, Astrid [Theoretical Astrophysics, California Institute of Technology, Pasadena, CA 91125 (United States); Puchwein, Ewald, E-mail: mshalaby@live.ca [Institute of Astronomy and Kavli Institute for Cosmology, University of Cambridge, Madingley Road, Cambridge, CB3 0HA (United Kingdom)

    2017-05-20

    Numerical heating in particle-in-cell (PIC) codes currently precludes the accurate simulation of cold, relativistic plasma over long periods, severely limiting their applications in astrophysical environments. We present a spatially higher-order accurate relativistic PIC algorithm in one spatial dimension, which conserves charge and momentum exactly. We utilize the smoothness implied by the usage of higher-order interpolation functions to achieve a spatially higher-order accurate algorithm (up to the fifth order). We validate our algorithm against several test problems—thermal stability of stationary plasma, stability of linear plasma waves, and two-stream instability in the relativistic and non-relativistic regimes. Comparing our simulations to exact solutions of the dispersion relations, we demonstrate that SHARP can quantitatively reproduce important kinetic features of the linear regime. Our simulations have a superior ability to control energy non-conservation and avoid numerical heating in comparison to common second-order schemes. We provide a natural definition for convergence of a general PIC algorithm: the complement of physical modes captured by the simulation, i.e., those that lie above the Poisson noise, must grow commensurately with the resolution. This implies that it is necessary to simultaneously increase the number of particles per cell and decrease the cell size. We demonstrate that traditional ways for testing for convergence fail, leading to plateauing of the energy error. This new PIC code enables us to faithfully study the long-term evolution of plasma problems that require absolute control of the energy and momentum conservation.

  6. Deletion of PEA-15 in mice is associated with specific impairments of spatial learning abilities

    Directory of Open Access Journals (Sweden)

    Hale Gregory

    2009-11-01

    Full Text Available Abstract Background PEA-15 is a phosphoprotein that binds and regulates ERK MAP kinase and RSK2 and is highly expressed throughout the brain. PEA-15 alters c-Fos and CREB-mediated transcription as a result of these interactions. To determine if PEA-15 contributes to the function of the nervous system we tested mice lacking PEA-15 in a series of experiments designed to measure learning, sensory/motor function, and stress reactivity. Results We report that PEA-15 null mice exhibited impaired learning in three distinct spatial tasks, while they exhibited normal fear conditioning, passive avoidance, egocentric navigation, and odor discrimination. PEA-15 null mice also had deficient forepaw strength and in limited instances, heightened stress reactivity and/or anxiety. However, these non-cognitive variables did not appear to account for the observed spatial learning impairments. The null mice maintained normal weight, pain sensitivity, and coordination when compared to wild type controls. Conclusion We found that PEA-15 null mice have spatial learning disabilities that are similar to those of mice where ERK or RSK2 function is impaired. We suggest PEA-15 may be an essential regulator of ERK-dependent spatial learning.

  7. Thermodynamic reversibility and irreversibility of the reverse transformation in stabilized Cu-Zn-Al martensite

    International Nuclear Information System (INIS)

    Kustov, S.; Corro, M.; Pons, J.; Cesari, E.; Van Humbeeck, J.

    2006-01-01

    It has been shown that both pinning- (mechanical) and reordering-induced (chemical) stabilization components contribute to the overall stabilization effect. An algorithm has been developed for quantitative analysis of the chemical and mechanical stabilization components, using routine calorimetry results. The basic idea underlying this algorithm is that chemical and mechanical stabilization components stem, respectively, from the factors, affecting thermodynamically reversible and irreversible factors during the first reverse transformation of the stabilized martensite. On a thermodynamical level, application of the suggested algorithm has been illustrated using experimental calorimetry results for a Cu-Zn-Al alloy. Here we report analysis of pinning and reordering processes on a microscopic scale, using experimental data on non-linear anelasticity in the same Cu-Zn-Al alloy to track different spatial and temporal localization of these processes during martensite ageing

  8. Disentangling the Role of the MEC and LEC in the Processing of Spatial and Non-Spatial Information: Contribution of Lesion Studies

    Directory of Open Access Journals (Sweden)

    Etienne Save

    2017-10-01

    Full Text Available It is now widely accepted that the entorhinal cortex (EC plays a pivotal role in the processing of spatial information and episodic memory. The EC is segregated into two sub-regions, the medial EC (MEC and the lateral EC (LEC but a comprehensive understanding of their roles across multiple behavioral contexts remains unclear. Considering that it is still useful to investigate the impact of lesions of EC on behavior, we review the contribution of lesion approach to our knowledge of EC functions. We show that the MEC and LEC play different roles in the processing of spatial and non-spatial information. The MEC is necessary to the use of distal but not proximal landmarks during navigation and is crucial for path integration, in particular integration of linear movements. Consistent with predominant hypothesis, the LEC is important for combining the spatial and non-spatial aspects of the environment. However, object exploration studies suggest that the functional segregation between the MEC and the LEC is not as clearly delineated and is dependent on environmental and behavioral factors. Manipulation of environmental complexity and therefore of cognitive demand shows that the MEC and the LEC are not strictly necessary to the processing of spatial and non-spatial information. In addition we suggest that the involvement of these sub-regions can depend on the kind of behavior, i.e., navigation or exploration, exhibited by the animals. Thus, the MEC and the LEC work in a flexible manner to integrate the “what” and “where” information in episodic memory upstream the hippocampus.

  9. Energy Stability Analysis of Some Fully Discrete Numerical Schemes for Incompressible Navier–Stokes Equations on Staggered Grids

    KAUST Repository

    Chen, Huangxin

    2017-09-01

    In this paper we consider the energy stability estimates for some fully discrete schemes which both consider time and spatial discretizations for the incompressible Navier–Stokes equations. We focus on three kinds of fully discrete schemes, i.e., the linear implicit scheme for time discretization with the finite difference method (FDM) on staggered grids for spatial discretization, pressure-correction schemes for time discretization with the FDM on staggered grids for the solutions of the decoupled velocity and pressure equations, and pressure-stabilization schemes for time discretization with the FDM on staggered grids for the solutions of the decoupled velocity and pressure equations. The energy stability estimates are obtained for the above each fully discrete scheme. The upwind scheme is used in the discretization of the convection term which plays an important role in the design of unconditionally stable discrete schemes. Numerical results are given to verify the theoretical analysis.

  10. Sequential bottom-up assembly of mechanically stabilized synthetic cells by microfluidics

    Science.gov (United States)

    Weiss, Marian; Frohnmayer, Johannes Patrick; Benk, Lucia Theresa; Haller, Barbara; Janiesch, Jan-Willi; Heitkamp, Thomas; Börsch, Michael; Lira, Rafael B.; Dimova, Rumiana; Lipowsky, Reinhard; Bodenschatz, Eberhard; Baret, Jean-Christophe; Vidakovic-Koch, Tanja; Sundmacher, Kai; Platzman, Ilia; Spatz, Joachim P.

    2018-01-01

    Compartments for the spatially and temporally controlled assembly of biological processes are essential towards cellular life. Synthetic mimics of cellular compartments based on lipid-based protocells lack the mechanical and chemical stability to allow their manipulation into a complex and fully functional synthetic cell. Here, we present a high-throughput microfluidic method to generate stable, defined sized liposomes termed `droplet-stabilized giant unilamellar vesicles (dsGUVs)’. The enhanced stability of dsGUVs enables the sequential loading of these compartments with biomolecules, namely purified transmembrane and cytoskeleton proteins by microfluidic pico-injection technology. This constitutes an experimental demonstration of a successful bottom-up assembly of a compartment with contents that would not self-assemble to full functionality when simply mixed together. Following assembly, the stabilizing oil phase and droplet shells are removed to release functional self-supporting protocells to an aqueous phase, enabling them to interact with physiologically relevant matrices.

  11. Spatial variability of aggregate stability in latosols under sugarcane Variabilidade espacial da estabilidade de agregados em latossolos sob cultivo de cana-de-açúcar

    Directory of Open Access Journals (Sweden)

    Zigomar Menezes de Souza

    2009-04-01

    Full Text Available The spatial variability of soils under a same management system is differentiated, as expressed in the properties. The spatial variability of aggregate stability of a eutrophic Red Latosol (ERL and a dystrophic Red Latosol (DRL under sugarcane was characterized. Samples were collected in a regular 10 m grid, in the layers 0.0-0.2 and 0.2-0.4 m, with 100 points per area, and the following properties were determined: geometric mean diameter (GMD of aggregates, mean weight diameter (MWD of aggregates, percent of aggregates in the > 2.0 mm class and organic matter (OM content. The eutrophic Red Latosol (ERL had a higher aggregate stability thn the dystrophic Red Latosol (DRL, which may be attributed to the higher clay and OM content and the gibbsitic mineralogy of this soil class. The differentiated evolution of the studied Oxisols explains the wider range and lower variation coefficient and variability, for all properties studied in the eutrophic Red Latosol.Solos submetidos ao mesmo sistema de manejo manifestam variabilidade espacial diferenciada de seus atributos. A variabilidade espacial da estabilidade de agregados foi caracterizada em um Latossolo Vermelho distrófico e Latossolo Vermelho eutroférrico, sob cultivo de cana-de-açúcar. Foram realizadas amostragens de terra nos pontos de interseção de uma malha de 10 x 10 linhas, espaçadas de 10 m, totalizando 100 pontos de amostragem por área, coletadas nas camadas de 0,0-0,2 e 0,2-0,4 m de profundidade, para determinação de diâmetro médio geométrico (DMG, diâmetro médio ponderado (DMP, agregados na classe >2,0 mm e teor de matéria orgânica do solo. O Latossolo Vermelho eutroférrico apresenta maior estabilidade de agregados quando comparado com o Latossolo Vermelho distrófico, condizente com o maior teor de argila, matéria orgânica e mineralogia gibbsítica. A evolução diferenciada dos Latossolos estudados explica os maiores alcances, o menor coeficiente de variação (CV e

  12. Investigating Design Research Landscapes through Exhibition

    DEFF Research Database (Denmark)

    Jönsson, Li; Hansen, Flemming Tvede; Mäkelä, Maarit

    2013-01-01

    What characterizes a design research exhibition compared to a traditional design and art exhibition? How do you show the very materialities of the design experiments as a means for communicating knowledge of research and of practice? How do you present, review and utilize such an exhibition......? With those questions in mind, the intention and challenge for the Nordes 2013 Design Research Exhibition was to expand on current notions of staging research enquires in design research conference contexts. Artefacts, installations, performances, and other materialities that relate to the theme...... of the conference - Experiments in Design Research – were displayed as tools to express and communicate different design research enquires. Through this paper we will describe the Nordes exhibition as a specific case that renders questions visible in relation to how to utilize a design research exhibition...

  13. Present status of mirror stability theory

    International Nuclear Information System (INIS)

    Baldwin, D.E.; Berk, H.L.; Byers, J.A.

    1976-01-01

    A status report of microinstability as it applies to 2XIIB and MX theory for mirror machines is presented. It is shown that quasilinear computations reproduce many of the parameters observed in the 2XIIB experiment. In regard to large mirror machines, there are presented detailed calculations of the linear theory of the drift cyclotron loss-cone mode, with inhomogeneous geometry and nonlinear diffusive effects. Further, the stability of a mirror machine to the Alfven ion-cyclotron instability is assessed, and the Baldwin-Callen diffusion is estimated for a spatially varying plasma

  14. The exhibition of the other: tradition, memory and colonialism in museums in Mexico

    Directory of Open Access Journals (Sweden)

    Mario Ruffer

    2014-12-01

    Full Text Available This article starts from the notion of "complex exhibitorio" on classical pedagogical function of the Western Museum (historical and ethnographic, and reviewed in, specifically Mexican contemporary Latin American contexts. The text contrasts ethnographic work in community museums with certain aspects of the Boards of ethnography at the National Museum of Anthropology in Mexico. The central thesis seeks to demonstrate is that the current rhetoric of post-colonial heritage and "cultural diversity" environments, still using the logic of exhibitorio complex but with a different mechanism and the classical notion of early twentieth century end. No longer try to exhibit the feats of the modern order and national construction, but a poetic return. Tradition would no longer fixed forever in the national museum in the capital, but that is installed on the spatial distance of the town or village: those who were the subject of museum and exhibition become subject to production of a look and an order. Finally he asks: have really moved the mechanisms defined and retained authority over cultural heritage?

  15. Does stability in local community composition depend on temporal variation in rates of dispersal and connectivity?

    Science.gov (United States)

    Valanko, Sebastian; Norkko, Joanna; Norkko, Alf

    2015-04-01

    In ecology understanding variation in connectivity is central for how biodiversity is maintained. Field studies on dispersal and temporal dynamics in community regulating processes are, however, rare. We test the short-term temporal stability in community composition in a soft-sediment benthic community by determining among-sampling interval similarity in community composition. We relate stability to in situ measures of connectivity (wind, wave, current energy) and rates of dispersal (quantified in different trap types). Waves were an important predictor of when local community taxa are most likely to disperse in different trap-types, suggesting that wave energy is important for connectivity in a region. Community composition at the site was variable and changed stochastically over time. We found changes in community composition (occurrence, abundance, dominance) to be greater at times when connectivity and rates of dispersal were low. In response to periods of lower connectedness dominant taxa in the local community only exhibited change in their relative abundance. In contrast, locally less abundant taxa varied in both their presence, as well as in relative abundance. Constancy in connectivity and rates of dispersal promotes community stability and persistence, suggesting that local community composition will be impacted by changes in the spatial extent over which immigration and emigration operates in the region. Few empirical studies have actually measured dispersal directly in a multi-species context to demonstrate the role it plays in maintaining local community structure. Even though our study does not evaluate coexistence over demographic time scales, it importantly demonstrates that dispersal is not only important in initial recruitment or following a disturbance, but also key in maintaining local community composition.

  16. Cooperation in carbon source degradation shapes spatial self-organization of microbial consortia on hydrated surfaces

    OpenAIRE

    Tecon, Robin; Or, Dani

    2017-01-01

    Mounting evidence suggests that natural microbial communities exhibit a high level of spatial organization at the micrometric scale that facilitate ecological interactions and support biogeochemical cycles. Microbial patterns are difficult to study definitively in natural environments due to complex biodiversity, observability and variable physicochemical factors. Here, we examine how trophic dependencies give rise to self-organized spatial patterns of a well-defined bacterial consortium grow...

  17. Metal-free, single-polymer device exhibits resistive memory effect

    KAUST Repository

    Bhansali, Unnat Sampatraj; Khan, Yasser; Cha, Dong Kyu; Almadhoun, Mahmoud N.; Li, Ruipeng; Chen, Long; Amassian, Aram; Odeh, Ihab N.; Alshareef, Husam N.

    2013-01-01

    All-polymer, write-once-read-many times resistive memory devices have been fabricated on flexible substrates using a single polymer, poly(3,4- ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS). Spin-cast or inkjet-printed films of solvent-modified PEDOT:PSS are used as electrodes, while the unmodified or as-is PEDOT:PSS is used as the semiconducting active layer. The all-polymer devices exhibit an irreversible but stable transition from a low resistance state (ON) to a high resistance state (OFF) at low voltages caused by an electric-field-induced morphological rearrangement of PEDOT and PSS at the electrode interface. However, in the metal-PEDOT:PSS-metal devices, we have shown a metal filament formation switching the device from an initial high resistance state (OFF) to the low resistance state (ON). The all-PEDOT:PSS memory device has low write voltages (<3 V), high ON/OFF ratio (>10 3), good retention characteristics (>10 000 s), and stability in ambient storage (>3 months). © 2013 American Chemical Society.

  18. Metal-free, single-polymer device exhibits resistive memory effect

    KAUST Repository

    Bhansali, Unnat Sampatraj

    2013-12-23

    All-polymer, write-once-read-many times resistive memory devices have been fabricated on flexible substrates using a single polymer, poly(3,4- ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS). Spin-cast or inkjet-printed films of solvent-modified PEDOT:PSS are used as electrodes, while the unmodified or as-is PEDOT:PSS is used as the semiconducting active layer. The all-polymer devices exhibit an irreversible but stable transition from a low resistance state (ON) to a high resistance state (OFF) at low voltages caused by an electric-field-induced morphological rearrangement of PEDOT and PSS at the electrode interface. However, in the metal-PEDOT:PSS-metal devices, we have shown a metal filament formation switching the device from an initial high resistance state (OFF) to the low resistance state (ON). The all-PEDOT:PSS memory device has low write voltages (<3 V), high ON/OFF ratio (>10 3), good retention characteristics (>10 000 s), and stability in ambient storage (>3 months). © 2013 American Chemical Society.

  19. Spatial pattern and ecological process in the coffee agroforestry system.

    Science.gov (United States)

    Perfecto, Ivette; Vandermeer, John

    2008-04-01

    The coffee agroforestry system provides an ideal platform for the study of spatial ecology. The uniform pattern of the coffee plants and shade trees allows for the study of pattern generation through intrinsic biological forces rather than extrinsic habitat patchiness. Detailed studies, focusing on a key mutualism between an ant (Azteca instabilis) and a scale insect (Coccus viridis), conducted in a 45-ha plot in a coffee agroforestry system have provided insights into (1) the quantitative evaluation of spatial pattern of the scale insect Coccus viridis on coffee bushes, (2) the mechanisms for the generation of patterns through the combination of local satellite ant nest formation and regional control from natural enemies, and (3) the consequences of the spatial pattern for the stability of predator-prey (host-parasitoid) systems, for a key coccinelid beetle preying on the scale insects and a phorid fly parasitoid parasitizing the ant.

  20. Statistical mechanics of spatial evolutionary games

    International Nuclear Information System (INIS)

    Miekisz, Jacek

    2004-01-01

    We discuss the long-run behaviour of stochastic dynamics of many interacting players in spatial evolutionary games. In particular, we investigate the effect of the number of players and the noise level on the stochastic stability of Nash equilibria. We discuss similarities and differences between systems of interacting players maximizing their individual payoffs and particles minimizing their interaction energy. We use concepts and techniques of statistical mechanics to study game-theoretic models. In order to obtain results in the case of the so-called potential games, we analyse the thermodynamic limit of the appropriate models of interacting particles

  1. Synchrony, waves and ripple in spatially coupled Kuramoto oscillators with Mexican hat connectivity.

    Science.gov (United States)

    Heitmann, Stewart; Ermentrout, G Bard

    2015-06-01

    Spatiotemporal waves of synchronized activity are known to arise in oscillatory neural networks with lateral inhibitory coupling. How such patterns respond to dynamic changes in coupling strength is largely unexplored. The present study uses analysis and simulation to investigate the evolution of wave patterns when the strength of lateral inhibition is varied dynamically. Neural synchronization was modeled by a spatial ring of Kuramoto oscillators with Mexican hat lateral coupling. Broad bands of coexisting stable wave solutions were observed at all levels of inhibition. The stability of these waves was formally analyzed in both the infinite ring and the finite ring. The broad range of multi-stability predicted hysteresis in transitions between neighboring wave solutions when inhibition is slowly varied. Numerical simulation confirmed the predicted transitions when inhibition was ramped down from a high initial value. However, non-wave solutions emerged from the uniform solution when inhibition was ramped upward from zero. These solutions correspond to spatially periodic deviations of phase that we call ripple states. Numerical continuation showed that stable ripple states emerge from synchrony via a supercritical pitchfork bifurcation. The normal form of this bifurcation was derived analytically, and its predictions compared against the numerical results. Ripple states were also found to bifurcate from wave solutions, but these were locally unstable. Simulation also confirmed the existence of hysteresis and ripple states in two spatial dimensions. Our findings show that spatial synchronization patterns can remain structurally stable despite substantial changes in network connectivity.

  2. Quadri-stability of a spatially ambiguous auditory illusion

    Directory of Open Access Journals (Sweden)

    Constance May Bainbridge

    2015-01-01

    Full Text Available In addition to vision, audition plays an important role in sound localization in our world. One way we estimate the motion of an auditory object moving towards or away from us is from changes in volume intensity. However, the human auditory system has unequally distributed spatial resolution, including difficulty distinguishing sounds in front versus behind the listener. Here, we introduce a novel quadri-stable illusion, the Transverse-and-Bounce Auditory Illusion, which combines front-back confusion with changes in volume levels of a nonspatial sound to create ambiguous percepts of an object approaching and withdrawing from the listener. The sound can be perceived as traveling transversely from front to back or back to front, or bouncing to remain exclusively in front of or behind the observer. Here we demonstrate how human listeners experience this illusory phenomenon by comparing ambiguous and unambiguous stimuli for each of the four possible motion percepts. When asked to rate their confidence in perceiving each sound’s motion, participants reported equal confidence for the illusory and unambiguous stimuli. Participants perceived all four illusory motion percepts, and could not distinguish the illusion from the unambiguous stimuli. These results show that this illusion is effectively quadri-stable. In a second experiment, the illusory stimulus was looped continuously in headphones while participants identified its perceived path of motion to test properties of perceptual switching, locking, and biases. Participants were biased towards perceiving transverse compared to bouncing paths, and they became perceptually locked into alternating between front-to-back and back-to-front percepts, perhaps reflecting how auditory objects commonly move in the real world. This multi-stable auditory illusion opens opportunities for studying the perceptual, cognitive, and neural representation of objects in motion, as well as exploring multimodal perceptual

  3. A mini-exhibition with maximum content

    CERN Multimedia

    Laëtitia Pedroso

    2011-01-01

    The University of Budapest has been hosting a CERN mini-exhibition since 8 May. While smaller than the main travelling exhibition it has a number of major advantages: its compact design alleviates transport difficulties and makes it easier to find suitable venues in the Member States. Its content can be updated almost instantaneously and it will become even more interactive and high-tech as time goes by.   The exhibition on display in Budapest. The purpose of CERN's new mini-exhibition is to be more interactive and easier to install. Due to its size, the main travelling exhibition cannot be moved around quickly, which is why it stays in the same country for 4 to 6 months. But this means a long waiting list for the other Member States. To solve this problem, the Education Group has designed a new exhibition, which is smaller and thus easier to install. Smaller maybe, but no less rich in content, as the new exhibition conveys exactly the same messages as its larger counterpart. However, in the slimm...

  4. Using three-dimensional plant root architecture in models of shallow-slope stability.

    Science.gov (United States)

    Danjon, Frédéric; Barker, David H; Drexhage, Michael; Stokes, Alexia

    2008-05-01

    The contribution of vegetation to shallow-slope stability is of major importance in landslide-prone regions. However, existing slope stability models use only limited plant root architectural parameters. This study aims to provide a chain of tools useful for determining the contribution of tree roots to soil reinforcement. Three-dimensional digitizing in situ was used to obtain accurate root system architecture data for mature Quercus alba in two forest stands. These data were used as input to tools developed, which analyse the spatial position of roots, topology and geometry. The contribution of roots to soil reinforcement was determined by calculating additional soil cohesion using the limit equilibrium model, and the factor of safety (FOS) using an existing slope stability model, Slip4Ex. Existing models may incorrectly estimate the additional soil cohesion provided by roots, as the spatial position of roots crossing the potential slip surface is usually not taken into account. However, most soil reinforcement by roots occurs close to the tree stem and is negligible at a distance >1.0 m from the tree, and therefore global values of FOS for a slope do not take into account local slippage along the slope. Within a forest stand on a landslide-prone slope, soil fixation by roots can be minimal between uniform rows of trees, leading to local soil slippage. Therefore, staggered rows of trees would improve overall slope stability, as trees would arrest the downward movement of soil. The chain of tools consisting of both software (free for non-commercial use) and functions available from the first author will enable a more accurate description and use of root architectural parameters in standard slope stability analyses.

  5. Ligand-Stabilized Reduced-Dimensionality Perovskites

    KAUST Repository

    Quan, Li Na; Yuan, Mingjian; Comin, Riccardo; Voznyy, Oleksandr; Beauregard, Eric M.; Hoogland, Sjoerd; Buin, Andrei; Kirmani, Ahmad R.; Zhao, Kui; Amassian, Aram; Kim, Dong Ha; Sargent, Edward H.

    2016-01-01

    Metal halide perovskites have rapidly advanced thin film photovoltaic performance; as a result, the materials’ observed instabilities urgently require a solution. Using density functional theory (DFT), we show that a low energy of formation, exacerbated in the presence of humidity, explains the propensity of perovskites to decompose back into their precursors. We find, also using DFT, that intercalation of phenylethylammonium between perovskite layers introduces quantitatively appreciable van der Waals interactions; and these drive an increased formation energy and should therefore improve material stability. Here we report the reduced-dimensionality (quasi-2D) perovskite films that exhibit improved stability while retaining the high performance of conventional three-dimensional perovskites. Continuous tuning of the dimensionality, as assessed using photophysical studies, is achieved by the choice of stoichiometry in materials synthesis. We achieved the first certified hysteresis-free solar power conversion in a planar perovskite solar cell, obtaining a 15.3% certified PCE, and observe greatly improved performance longevity.

  6. Ligand-Stabilized Reduced-Dimensionality Perovskites

    KAUST Repository

    Quan, Li Na

    2016-02-03

    Metal halide perovskites have rapidly advanced thin film photovoltaic performance; as a result, the materials’ observed instabilities urgently require a solution. Using density functional theory (DFT), we show that a low energy of formation, exacerbated in the presence of humidity, explains the propensity of perovskites to decompose back into their precursors. We find, also using DFT, that intercalation of phenylethylammonium between perovskite layers introduces quantitatively appreciable van der Waals interactions; and these drive an increased formation energy and should therefore improve material stability. Here we report the reduced-dimensionality (quasi-2D) perovskite films that exhibit improved stability while retaining the high performance of conventional three-dimensional perovskites. Continuous tuning of the dimensionality, as assessed using photophysical studies, is achieved by the choice of stoichiometry in materials synthesis. We achieved the first certified hysteresis-free solar power conversion in a planar perovskite solar cell, obtaining a 15.3% certified PCE, and observe greatly improved performance longevity.

  7. Accuration of Time Series and Spatial Interpolation Method for Prediction of Precipitation Distribution on the Geographical Information System

    Science.gov (United States)

    Prasetyo, S. Y. J.; Hartomo, K. D.

    2018-01-01

    The Spatial Plan of the Province of Central Java 2009-2029 identifies that most regencies or cities in Central Java Province are very vulnerable to landslide disaster. The data are also supported by other data from Indonesian Disaster Risk Index (In Indonesia called Indeks Risiko Bencana Indonesia) 2013 that suggest that some areas in Central Java Province exhibit a high risk of natural disasters. This research aims to develop an application architecture and analysis methodology in GIS to predict and to map rainfall distribution. We propose our GIS architectural application of “Multiplatform Architectural Spatiotemporal” and data analysis methods of “Triple Exponential Smoothing” and “Spatial Interpolation” as our significant scientific contribution. This research consists of 2 (two) parts, namely attribute data prediction using TES method and spatial data prediction using Inverse Distance Weight (IDW) method. We conduct our research in 19 subdistricts in the Boyolali Regency, Central Java Province, Indonesia. Our main research data is the biweekly rainfall data in 2000-2016 Climatology, Meteorology, and Geophysics Agency (In Indonesia called Badan Meteorologi, Klimatologi, dan Geofisika) of Central Java Province and Laboratory of Plant Disease Observations Region V Surakarta, Central Java. The application architecture and analytical methodology of “Multiplatform Architectural Spatiotemporal” and spatial data analysis methodology of “Triple Exponential Smoothing” and “Spatial Interpolation” can be developed as a GIS application framework of rainfall distribution for various applied fields. The comparison between the TES and IDW methods show that relative to time series prediction, spatial interpolation exhibit values that are approaching actual. Spatial interpolation is closer to actual data because computed values are the rainfall data of the nearest location or the neighbour of sample values. However, the IDW’s main weakness is that some

  8. Stability properties of cold blanket systems for current driven modes

    International Nuclear Information System (INIS)

    Ohlsson, D.

    1977-12-01

    The stability problem of the boundary regions of cold blanket systems with induced currents parallel to the lines of force is formulated. Particular interest is focused on two types of modes: first electrostatic modes driven by the combined effects of a transverse resistivity gradient due to a spatially non-uniform electron temperature and a longitudinal current, second electromagnetic kink like modes driven by the torque arising from a transverse current density gradient and magnetic field perturbations. It is found that the combination of various dissipative and neutral gas effects introduces strong stabilizing effects within specific parameter ranges. For particular steady-state models investigated it is shown that these effects become of importance in laboratory plasmas at relatively high densities, low temperatures and moderate magnetic field strengths. Stability diagrams based on specific steady-state cold plasma blanket models will be presented

  9. Enhanced thermal stability of RuO2/polyimide interface for flexible device applications

    Science.gov (United States)

    Music, Denis; Schmidt, Paul; Chang, Keke

    2017-09-01

    We have studied the thermal stability of RuO2/polyimide (Kapton) interface using experimental and theoretical methods. Based on calorimetric and spectroscopic analyses, this inorganic-organic system does not exhibit any enthalpic peaks as well as all bonds in RuO2 and Kapton are preserved up to 500 °C. In addition, large-scale density functional theory based molecular dynamics, carried out in the same temperature range, validates the electronic structure and points out that numerous Ru-C and a few Ru-O covalent/ionic bonds form across the RuO2/Kapton interface. This indicates strong adhesion, but there is no evidence of Kapton degradation upon thermal excitation. Furthermore, RuO2 does not exhibit any interfacial bonds with N and H in Kapton, providing additional evidence for the thermal stability notion. It is suggested that the RuO2/Kapton interface is stable due to aromatic architecture of Kapton. This enhanced thermal stability renders Kapton an appropriate polymeric substrate for RuO2 containing systems in various applications, especially for flexible microelectronic and energy devices.

  10. Stability of Anthocyanin Sensitized TiO2 Photoelectrochemical (PEC ...

    African Journals Online (AJOL)

    Solar cells fabricated from these electrodes gave overall conversion efficiencies of 3.16% for delphinidin purple and 2.97% for C35D. RuL dye sensitized solar cell gave 4.84%. The cells\\' stability performance in terms of photovoltage was found to drop with time of exposure. However the cells still exhibited I-V characteristics ...

  11. Assessing the accuracy and stability of variable selection methods for random forest modeling in ecology.

    Science.gov (United States)

    Fox, Eric W; Hill, Ryan A; Leibowitz, Scott G; Olsen, Anthony R; Thornbrugh, Darren J; Weber, Marc H

    2017-07-01

    Random forest (RF) modeling has emerged as an important statistical learning method in ecology due to its exceptional predictive performance. However, for large and complex ecological data sets, there is limited guidance on variable selection methods for RF modeling. Typically, either a preselected set of predictor variables are used or stepwise procedures are employed which iteratively remove variables according to their importance measures. This paper investigates the application of variable selection methods to RF models for predicting probable biological stream condition. Our motivating data set consists of the good/poor condition of n = 1365 stream survey sites from the 2008/2009 National Rivers and Stream Assessment, and a large set (p = 212) of landscape features from the StreamCat data set as potential predictors. We compare two types of RF models: a full variable set model with all 212 predictors and a reduced variable set model selected using a backward elimination approach. We assess model accuracy using RF's internal out-of-bag estimate, and a cross-validation procedure with validation folds external to the variable selection process. We also assess the stability of the spatial predictions generated by the RF models to changes in the number of predictors and argue that model selection needs to consider both accuracy and stability. The results suggest that RF modeling is robust to the inclusion of many variables of moderate to low importance. We found no substantial improvement in cross-validated accuracy as a result of variable reduction. Moreover, the backward elimination procedure tended to select too few variables and exhibited numerous issues such as upwardly biased out-of-bag accuracy estimates and instabilities in the spatial predictions. We use simulations to further support and generalize results from the analysis of real data. A main purpose of this work is to elucidate issues of model selection bias and instability to ecologists interested in

  12. Integral equation based stability analysis of short wavelength drift modes in tokamaks

    International Nuclear Information System (INIS)

    Hirose, A.; Elia, M.

    2003-01-01

    Linear stability of electron skin-size drift modes in collisionless tokamak discharges has been investigated in terms of electromagnetic, kinetic integral equations in which neither ions nor electrons are assumed to be adiabatic. A slab-like ion temperature gradient mode persists in such a short wavelength regime. However, toroidicity has a strong stabilizing influence on this mode. In the electron branch, the toroidicity induced skin-size drift mode previously predicted in terms of local kinetic analysis has been recovered. The mode is driven by positive magnetic shear and strongly stabilized for negative shear. The corresponding mixing length anomalous thermal diffusivity exhibits favourable isotope dependence. (author)

  13. Liquid-bridge stability and breakup on surfaces with contact-angle hysteresis.

    Science.gov (United States)

    Akbari, Amir; Hill, Reghan J

    2016-08-10

    We study the stability and breakup of liquid bridges with a free contact line on surfaces with contact-angle hysteresis (CAH) under zero-gravity conditions. Non-ideal surfaces exhibit CAH because of surface imperfections, by which the constraints on three-phase contact lines are influenced. Given that interfacial instabilities are constraint-sensitive, understanding how CAH affects the stability and breakup of liquid bridges is crucial for predicting the drop size in contact-drop dispensing. Unlike ideal surfaces on which contact lines are always free irrespective of surface wettability, contact lines may undergo transitions from pinned to free and vice versa during drop deposition on non-ideal surfaces. Here, we experimentally and theoretically examine how stability and breakup are affected by CAH, highlighting cases where stability is lost during a transition from a pinned-pinned (more constrained) to pinned-free (less constrained) interface-rather than a critical state. This provides a practical means of expediting or delaying stability loss. We also demonstrate how the dynamic contact angle can control the contact-line radius following stability loss.

  14. Cross-Industry Spatially Localized Innovation Networks

    Directory of Open Access Journals (Sweden)

    Aleksandr Evseevich Karlik

    2016-12-01

    Full Text Available This article’s objective is to develop conceptual approach to the study of key decision-making factors of cross-industry spatially localized innovation networks regularities by the application of quantitative and qualitative data of St. Petersburg Innovation and Technology Cluster of Machinery Manufacturing and Metalworking. The paper is based on the previous research findings which conclude that such networks have a set of opportunities and constraints for innovation. The hypothesis is that in the clusters, representing a special type of these networks, the spatial proximity partly offsets the negative impact of industrial distance. The authors propose a structural and logical model of strategic decision-making to analyze these effects on innovation. They specify network’s influences on performance: cognitive diversity; knowledge and expertise; structural autonomy and equivalence. The model is applied to spatially localized cross-industry cluster and then improved in accordance with the obtained results for accounting resource flows. It allowed to take into account the dynamics of innovation activity and to develop the practical implications in the particular business context. The analysis identified the peculiarities of spatially localized crossindustry innovation cooperation in perspective of the combinations of tangible resources, information and other intangible resources for the renewal of mature industries. The research results can be used in business as well as in industrial and regional economic policy. In the conclusion, the article outlines future research directions: a comprehensive empirical study with the analysis of data on the factors of cross-industry cooperation which were identified in this paper with testing of causal relations; the developing an approach to the study of spatially localized networks based on the exchange of primary resources in the economic system stability framework.

  15. Effect of a cathode buffer layer on the stability of organic solar cells

    International Nuclear Information System (INIS)

    Wang, Danbei; Zeng, Wenjin; Chen, Shilin; Su, Xiaodan; Wang, Jin; Zhang, Hongmei

    2015-01-01

    We present the effect of a cathode buffer layer on the performance and stability of organic photovoltaics (OPVs) based on a blend of poly(3-hexylthiophene) (P3HT) and [6,6]-phenyl C61-butyric acid methyl ester (PCBM). Six kinds of cathode buffer layers, i.e. lithium fluoride, sodium chloride, NaCl/Mg, tris-(8-hydroxy-quinoline) aluminum, bathocuproine and 1,3,5-tris(2-N-phenylbenzimidazolyl)benzene, were inserted between the photoactive layer and an Al cathode, which played a dominant role in the device’s performance. Devices with the cathode buffer layers above exhibited improved performance. The degradation of these devices with encapsulation was further investigated in an inert atmosphere. The results indicated that devices with inorganic cathode buffer layers exhibited better stability than those with organic cathode buffer layers. (paper)

  16. Spatial bias and uncertainty in numerical weather predictions for urban runoff forecasts with long time horizons

    DEFF Research Database (Denmark)

    Pedersen, Jonas Wied; Courdent, Vianney Augustin Thomas; Vezzaro, Luca

    2017-01-01

    Numerical Weather Predictions (NWP) can be used to forecast urban runoff with long lead times. However, NWP exhibit large spatial uncertainties and using forecasted precipitation directly above the catchment might therefore not be an ideal approach in an online setup. We use the Danish...... Meteorological Institute’s NWP ensemble and investigate a large spatial neighborhood around the catchment over a two-year period. When compared against in-sewer observations, runoff forecasts forced with precipitation from north-east of the catchment are most skillful. This highlights spatial biases...

  17. Habitat stability, predation risk and ‘memory syndromes’

    OpenAIRE

    S. Dalesman; A. Rendle; S.R.X. Dall

    2015-01-01

    Habitat stability and predation pressure are thought to be major drivers in the evolutionary maintenance of behavioural syndromes, with trait covariance only occurring within specific habitats. However, animals also exhibit behavioural plasticity, often through memory formation. Memory formation across traits may be linked, with covariance in memory traits (memory syndromes) selected under particular environmental conditions. This study tests whether the pond snail, Lymnaea stagnalis, demonst...

  18. Stabilization of Live Attenuated Influenza Vaccines by Freeze Drying, Spray Drying, and Foam Drying.

    Science.gov (United States)

    Lovalenti, Phillip M; Anderl, Jeff; Yee, Luisa; Nguyen, Van; Ghavami, Behnaz; Ohtake, Satoshi; Saxena, Atul; Voss, Thomas; Truong-Le, Vu

    2016-05-01

    The goal of this research is to develop stable formulations for live attenuated influenza vaccines (LAIV) by employing the drying methods freeze drying, spray drying, and foam drying. Formulated live attenuated Type-A H1N1 and B-strain influenza vaccines with a variety of excipient combinations were dried using one of the three drying methods. Process and storage stability at 4, 25 and 37°C of the LAIV in these formulations was monitored using a TCID50 potency assay. Their immunogenicity was also evaluated in a ferret model. The thermal stability of H1N1 vaccine was significantly enhanced through application of unique formulation combinations and drying processes. Foam dried formulations were as much as an order of magnitude more stable than either spray dried or freeze dried formulations, while exhibiting low process loss and full retention of immunogenicity. Based on long-term stability data, foam dried formulations exhibited a shelf life at 4, 25 and 37°C of >2, 1.5 years and 4.5 months, respectively. Foam dried LAIV Type-B manufactured using the same formulation and process parameters as H1N1 were imparted with a similar level of stability. Foam drying processing methods with appropriate selection of formulation components can produce an order of magnitude improvement in LAIV stability over other drying methods.

  19. The spatial information system EramSIS in the service of geotechnical monitoring

    International Nuclear Information System (INIS)

    Heller, M.; Skrzyppek, J.; Croise, J.; Mauke, R.; Mohlfeld, M.

    2005-01-01

    Backfilling activities in the Morsleben radioactive waste repository (ERAM) began in 2003. They are necessary to stabilize the intensely mined central part of the repository. Thanks to geotechnical monitoring it is possible to ensure the local structural stability and the mandatory operational safety. The use of the integrated spatial information system EramSIS right from an early stage makes it possible to locate the great number of continuously acquired measurement results in a three-dimensional model on the computer screen. The interactive visualization proved to greatly facilitate the interpretation of the various types of information. (authors)

  20. On the Stability of the Finite Difference based Lattice Boltzmann Method

    KAUST Repository

    El-Amin, Mohamed; Sun, Shuyu; Salama, Amgad

    2013-01-01

    This paper is devoted to determining the stability conditions for the finite difference based lattice Boltzmann method (FDLBM). In the current scheme, the 9-bit two-dimensional (D2Q9) model is used and the collision term of the Bhatnagar- Gross-Krook (BGK) is treated implicitly. The implicitness of the numerical scheme is removed by introducing a new distribution function different from that being used. Therefore, a new explicit finite-difference lattice Boltzmann method is obtained. Stability analysis of the resulted explicit scheme is done using Fourier expansion. Then, stability conditions in terms of time and spatial steps, relaxation time and explicitly-implicitly parameter are determined by calculating the eigenvalues of the given difference system. The determined conditions give the ranges of the parameters that have stable solutions.

  1. On the Stability of the Finite Difference based Lattice Boltzmann Method

    KAUST Repository

    El-Amin, Mohamed

    2013-06-01

    This paper is devoted to determining the stability conditions for the finite difference based lattice Boltzmann method (FDLBM). In the current scheme, the 9-bit two-dimensional (D2Q9) model is used and the collision term of the Bhatnagar- Gross-Krook (BGK) is treated implicitly. The implicitness of the numerical scheme is removed by introducing a new distribution function different from that being used. Therefore, a new explicit finite-difference lattice Boltzmann method is obtained. Stability analysis of the resulted explicit scheme is done using Fourier expansion. Then, stability conditions in terms of time and spatial steps, relaxation time and explicitly-implicitly parameter are determined by calculating the eigenvalues of the given difference system. The determined conditions give the ranges of the parameters that have stable solutions.

  2. Dynamic stability and failure modes of slopes in discontinuous rock mass

    International Nuclear Information System (INIS)

    Shimizu, Yasuhiro; Aydan, O.; Ichikawa, Yasuaki; Kawamoto, Toshikazu.

    1988-01-01

    The stability of rock slopes during earthquakes are of great concern in rock engineering works such as highway, dam, and nuclear power station constructions. As rock mass in nature is usually discontinuous, the stability of rock slopes will be geverned by the spatial distribution of discontinuities in relation with the geometry of slope and their mechanical properties rather than the rock element. The authors have carried out some model tests on discontinuous rock slopes using three different model tests techniques in order to investigate the dynamic behaviour and failure modes of the slopes in discontinuous rock mass. This paper describes the findings and observations made on model rock slopes with various discontinuity patterns and slope geometry. In addition some stability criterions are developed and the calculated results are compared with those of experiments. (author)

  3. Applying spatial clustering analysis to a township-level social vulnerability assessment in Taiwan

    Directory of Open Access Journals (Sweden)

    Wen-Yen Lin

    2016-09-01

    Full Text Available The degree of social vulnerability may vary according to the conditions and backgrounds of different locations, yet spatial clustering phenomena may exist when nearby spatial units exhibit similar characteristics. This study applied spatial autocorrelation statistics to analyze the spatial association of vulnerability among townships in Taiwan. The vulnerability was first assessed on the basis of a social vulnerability index that was constructed using Fuzzy Delphi and analytic hierarchy process methods. Subsequently, the corresponding indicator variables were applied to calculate standardized vulnerability assessment scores by using government data. According to the results of the vulnerability assessment in which T scores were normalized, the distribution of social vulnerabilities varied among the townships. The scores were further analyzed using spatial autocorrelation statistics for spatial clustering of vulnerability distribution. The Local G statistic identified 42 significant spatial association pockets, whereas the Global G statistic indicated no spatial phenomenon of clustering. This phenomenon was verified and explained by applying Moran's I statistics to examine the homogeneity and heterogeneity of spatial associations. Although both statistics were originally designed to identify the existence of spatial clustering, they serve diverse purposes, and the results can be compared to obtain additional insights into the distribution patterns of social vulnerability.

  4. Stabilization and destabilization effects of the electric field on stochastic precipitate pattern

    NARCIS (Netherlands)

    Lagzi, István; Izsak, F.

    2004-01-01

    Stabilization and destabilization effects of an applied electric field on the Liesegang pattern formation in low concentration gradient were studied with numerical model simulations. In the absence of an electric field pattern formation exhibits increasingly stochastic behaviour as the initial

  5. Coastal fog and low cloud spatial patterns: do they indicate potential biodiversity refugia?

    Science.gov (United States)

    Torregrosa, A.

    2016-12-01

    Marine fog and low clouds transfer water and nutrients to coastal ecosystems through advection from the ocean and reduce heat effects by reflecting incoming shortwave radiation. These effects are known to benefit many species, vegetation communities, and habitats such as coastal redwood trees and their understory, maritime chaparral, and coastal streams harboring endangered salmon species. The California floristic region is the highest ranked hotspot in the U.S. and ranked 7th of 35 biodiversity hotspots worldwide in terms of the percent of its plant species that are found nowhere else (endemic). Many environmental drivers have been identified as contributing to California's remarkably high endemism and biodiversity, however, coastal low clouds have not typically been included. This could be due to the lack of data such as high resolution maps of coastal low cloud occurrence or the lack of long term records. Using a recent analysis of hourly National Weather Service satellite data, a stability index (SI) for coastal fog and low cloud cover was derived using two measures of variation and average summertime cloud cover to quantify long term spatial stability trends. Several discrete spatial clumps were identified that had both high temporal stability and high coastal low cloud cover. These areas show a strong correlation with a specific topographic landscape configuration with respect to wind direction. Point occurrence distribution maps of endemic coastal species were overlain with the SI to explore spatial correlation. The federally endangered species that showed very high spatial correlation included Yadon's Rein-orchid (Piperia yadonii), Monterey Spineflower (Chorizanthe pungens var. pungens), and Seaside Bird's-beak (Cordylanthus rigidus ssp. littoralis). Current estimated range maps are not consistent with the SI results suggesting a need to update estimated ranges. Biodiversity measures are being investigated in these areas to explore the hypothesis that they

  6. Conductivity and electrochemical stability of concentrated aqueous choline chloride solutions

    Science.gov (United States)

    Grishina, E. P.; Kudryakova, N. O.

    2017-10-01

    The conductivity and electrochemical stability of choline chloride (ChCl) solutions with water contents ranging from 20 to 39 wt % are studied. Exposing ChCl to moist ambient air yields a highly concentrated aqueous solution that, as an electrolyte, exhibits the properties and variations in conductivity with temperature and concentration characteristic of other similar systems. Its electrochemical stability window, determined by cyclic voltammetry, is comparable to that of ChCl-based deep eutectic solvents (DESs). Products of the electrolysis of ChCl‒H2O mixtures seem to be less toxic than those of Reline, Ethaline, and Maline.

  7. Visuo-Spatial Attention in ADHD Children: Investigating the Asymmetry

    Directory of Open Access Journals (Sweden)

    Faranak Aliabadi

    2011-04-01

    Full Text Available Objectives: The purpose of the present study was comparing visuo-spatial attention between children with Attention Deficit Hyperactivity Disorder-Inattentive (ADHD-I type and normal children. Methods: In this cross-sectional study fifteen (7-10 years of age children were classified with ADHD-I type and 15 normal children were matched for age, sex, and IQ. They were selected trough simple random sampling. Measurement tools were Wechsler Intelligence Scale for children 4th edition (WISC-IV, the Edinburgh Handedness Inventory and the Star Cancellation Test. Results: The results suggest that there is no significant difference between ADHD-I and normal children from the visuo-spatial standpoint (P>0.05. But three ADHD-I children exhibited signs of unilateral neglect. Discussion: Although, in this study the visuo-spatial attention was not different between ADHD-I group and normal group, considering this form of attention as an item in assessment and therapeutic interventions should not be neglected.

  8. Spatial and temporal variability of hyperspectral signatures of terrain

    Science.gov (United States)

    Jones, K. F.; Perovich, D. K.; Koenig, G. G.

    2008-04-01

    Electromagnetic signatures of terrain exhibit significant spatial heterogeneity on a range of scales as well as considerable temporal variability. A statistical characterization of the spatial heterogeneity and spatial scaling algorithms of terrain electromagnetic signatures are required to extrapolate measurements to larger scales. Basic terrain elements including bare soil, grass, deciduous, and coniferous trees were studied in a quasi-laboratory setting using instrumented test sites in Hanover, NH and Yuma, AZ. Observations were made using a visible and near infrared spectroradiometer (350 - 2500 nm) and hyperspectral camera (400 - 1100 nm). Results are reported illustrating: i) several difference scenes; ii) a terrain scene time series sampled over an annual cycle; and iii) the detection of artifacts in scenes. A principal component analysis indicated that the first three principal components typically explained between 90 and 99% of the variance of the 30 to 40-channel hyperspectral images. Higher order principal components of hyperspectral images are useful for detecting artifacts in scenes.

  9. Optimal explicit strong stability preserving Runge–Kutta methods with high linear order and optimal nonlinear order

    KAUST Repository

    Gottlieb, Sigal; Grant, Zachary; Higgs, Daniel

    2015-01-01

    High order spatial discretizations with monotonicity properties are often desirable for the solution of hyperbolic PDEs. These methods can advantageously be coupled with high order strong stability preserving time discretizations. The search

  10. Science Fiction Exhibits as STEM Gateways

    Science.gov (United States)

    Robie, Samantha

    Women continue to hold less than a quarter of all STEM jobs in the United States, prompting many museums to develop programs and exhibits with the express goal of interesting young girls in scientific fields. At the same time, a number of recent museum exhibits have harnessed the popularity of pop culture and science fiction in order to interest general audiences in STEM subject matter, as well as using the exhibits as springboards to expand or shift mission goals and focus. Because science fiction appears to be successful at raising interest in STEM fields, it may be an effective way to garner the interest of young girls in STEM in particular. This research seeks to describe the ways in which museums are currently using science fiction exhibits to interest young girls in STEM fields and careers. Research focused on four institutions across the country hosting three separate exhibits, and included staff interviews and content analysis of exhibit descriptions, promotional materials, a summative evaluation and supplementary exhibit productions. In some ways, science fiction exhibits do serve young girls, primarily through the inclusion of female role models, staff awareness, and prototype testing to ensure interactives are attractive to girls as well as to boys. However, STEM appears to be underutilized, which may be partly due to a concern within the field that the outcome of targeting a specific gender could be construed as "stereotyping".

  11. Aqueous clay suspensions stabilized by alginate fluid gels for coal spontaneous combustion prevention and control.

    Science.gov (United States)

    Qin, Botao; Ma, Dong; Li, Fanglei; Li, Yong

    2017-11-01

    We have developed aqueous clay suspensions stabilized by alginate fluid gels (AFG) for coal spontaneous combustion prevention and control. Specially, this study aimed to characterize the effect of AFG on the microstructure, static and dynamic stability, and coal fire inhibition performances of the prepared AFG-stabilized clay suspensions. Compared with aqueous clay suspensions, the AFG-stabilized clay suspensions manifest high static and dynamic stability, which can be ascribed to the formation of a robust three-dimensional gel network by AFG. The coal acceleration oxidation experimental results show that the prepared AFG-stabilized clay suspensions can improve the coal thermal stability and effectively inhibit the coal spontaneous oxidation process by increasing crossing point temperature (CPT) and reducing CO emission. The prepared low-cost and nontoxic AFG-stabilized clay suspensions, exhibiting excellent coal fire extinguishing performances, indicate great application potentials in coal spontaneous combustion prevention and control.

  12. Thermal stability engineering of Glomerella cingulata cutinase.

    Science.gov (United States)

    Chin, Iuan-Sheau; Abdul Murad, Abdul Munir; Mahadi, Nor Muhammad; Nathan, Sheila; Abu Bakar, Farah Diba

    2013-05-01

    Cutinase has been ascertained as a biocatalyst for biotechnological and industrial bioprocesses. The Glomerella cingulata cutinase was genetically modified to enhance its enzymatic performance to fulfill industrial requirements. Two sites were selected for mutagenesis with the aim of altering the surface electrostatics as well as removing a potentially deamidation-prone asparagine residue. The N177D cutinase variant was affirmed to be more resilient to temperature increase with a 2.7-fold increase in half-life at 50°C as compared with wild-type enzyme, while, the activity at 25°C is not compromised. Furthermore, the increase in thermal tolerance of this variant is accompanied by an increase in optimal temperature. Another variant, the L172K, however, exhibited higher enzymatic performance towards phenyl ester substrates of longer carbon chain length, yet its thermal stability is inversely affected. In order to restore the thermal stability of L172K, we constructed a L172K/N177D double variant and showed that these two mutations yield an improved variant with enhanced activity towards phenyl ester substrates and enhanced thermal stability. Taken together, our study may provide valuable information for enhancing catalytic performance and thermal stability in future engineering endeavors.

  13. Prenatal methylmercury exposure affects spatial vision in adult monkeys

    International Nuclear Information System (INIS)

    Burbacher, Thomas M.; Grant, Kimberly S.; Mayfield, David B.; Gilbert, Steven G.; Rice, Deborah C.

    2005-01-01

    Decades of research have demonstrated that exposure to methylmercury (MeHg), a ubiquitous environmental pollutant, can have both early and long-term neurobehavioral consequences in exposed offspring. The present study assessed visual functioning in adult macaque monkeys (Macaca fascicularis) exposed in utero to 0, 50, 70, or 90 μg/kg/day of MeHg hydroxide. Twenty-one full-term, normal birth weight offspring (9 controls, 12 exposed) were tested at approximately 11-14.5 years of age on a visual contrast sensitivity task. A forced-choice tracking procedure was utilized with spatial frequencies of 1, 4, 10, and 20 cycles per degree of visual angle. On each test session, a single spatial frequency was presented across five levels of contrast, each differing by 3 dB. Methylmercury-exposed monkeys exhibited reduced contrast sensitivity thresholds, particularly at the higher spatial frequencies. The degree of visual impairment was not related to MeHg body burden or clearance and almost half of the exposed animals were unimpaired. The results from this study demonstrate that chronic in utero MeHg exposure, at subclinical levels, is associated with permanent adverse effects on spatial vision in adult monkeys

  14. Temporal scaling and spatial statistical analyses of groundwater level fluctuations

    Science.gov (United States)

    Sun, H.; Yuan, L., Sr.; Zhang, Y.

    2017-12-01

    Natural dynamics such as groundwater level fluctuations can exhibit multifractionality and/or multifractality due likely to multi-scale aquifer heterogeneity and controlling factors, whose statistics requires efficient quantification methods. This study explores multifractionality and non-Gaussian properties in groundwater dynamics expressed by time series of daily level fluctuation at three wells located in the lower Mississippi valley, after removing the seasonal cycle in the temporal scaling and spatial statistical analysis. First, using the time-scale multifractional analysis, a systematic statistical method is developed to analyze groundwater level fluctuations quantified by the time-scale local Hurst exponent (TS-LHE). Results show that the TS-LHE does not remain constant, implying the fractal-scaling behavior changing with time and location. Hence, we can distinguish the potentially location-dependent scaling feature, which may characterize the hydrology dynamic system. Second, spatial statistical analysis shows that the increment of groundwater level fluctuations exhibits a heavy tailed, non-Gaussian distribution, which can be better quantified by a Lévy stable distribution. Monte Carlo simulations of the fluctuation process also show that the linear fractional stable motion model can well depict the transient dynamics (i.e., fractal non-Gaussian property) of groundwater level, while fractional Brownian motion is inadequate to describe natural processes with anomalous dynamics. Analysis of temporal scaling and spatial statistics therefore may provide useful information and quantification to understand further the nature of complex dynamics in hydrology.

  15. Economic agglomerations and spatio-temporal cycles in a spatial growth model with capital transport cost

    Science.gov (United States)

    Juchem Neto, J. P.; Claeyssen, J. C. R.; Pôrto Júnior, S. S.

    2018-03-01

    In this paper we introduce capital transport cost in a unidimensional spatial Solow-Swan model of economic growth with capital-induced labor migration, considered in an unbounded domain. Proceeding with a stability analysis, we show that there is a critical value for the capital transport cost where the dynamic behavior of the economy changes, provided that the intensity of capital-induced labor migration is strong enough. On the one hand, if the capital transport cost is higher than this critical value, the spatially homogeneous equilibrium of coexistence of the model is stable, and the economy converges to this spatially homogeneous state in the long run; on the other hand, if transport cost is lower than this critical value, the equilibrium is unstable, and the economy may develop different spatio-temporal dynamics, including the formation of stable economic agglomerations and spatio-temporal economic cycles, depending on the other parameters in the model. Finally, numerical simulations support the results of the stability analysis, and illustrate the spatio-temporal dynamics generated by the model, suggesting that the economy as a whole benefits from the formation of economic agglomerations and cycles, with a higher capital transport cost reducing this gain.

  16. Photowalk Exhibition opens at Microcosm

    CERN Document Server

    Katarina Anthony

    2011-01-01

    The winning photographs from the 2010 Global Particle Physics Photowalk competition will go on display at Microcosm from 11 February to 2 April. The exhibition is part of a global photography event taking place over three continents, with Photowalk exhibitions opening simultaneously at Fermilab in the US, KEK in Japan and here at CERN.   DESY wire chamber - First place people's choice; second place global jury competition. Photographer: Hans-Peter Hildebrandt  If you were one of the 1,300 photography lovers who voted in last year’s Photowalk competition, this exhibition is your chance to see the winning entries in print. The exhibition will take place in the downstairs gallery of Microcosm, overlooking the garden. 15 photographs will be on display, with each of the laboratories that participated in Photowalk represented by their 3 winning entries. Among them will be the “people’s choice” sunburst photo of a particle detector at DESY (Photo 1), and...

  17. Creating National Narrative: The Red Guard Art Exhibitions and the National Exhibitions in the Chinese Cultural Revolution 1966 - 1976

    Directory of Open Access Journals (Sweden)

    Winnie Tsang

    2014-06-01

    Full Text Available The artistic development in China experienced drastic changes during the Cultural Revolution from 1966 to 1976. Traditional Chinese art was denounced, whereas propaganda art became predominant in shaping the public’s loyalty towards the Communist Party and the country. Two major groups of art exhibitions emerged during the Revolution—the unofficial Red Guard art exhibitions organized by student activists in collaboration with local communes and art schools between 1966 and 1968, and the state-run national exhibitions from 1972 to 1975. These exhibitions were significant to this period because they were held frequently in the capital city Beijing and occasionally elsewhere, and through art they presented unique revolutionary beliefs to the Chinese people in a public setting. While the Red Guard art exhibitions and the national exhibitions certainly created different national narratives, I argue that the national exhibitions were in fact an attempt to revise the national narrative created by the Red Guard art exhibitions in order to re-establish a more utopian, consistent, and official national narrative. This paper unravels the intricate relationship between the two groups of exhibitions by comparing their exhibition venues, ideological focuses, work selection and quality editing. 

  18. Effect of Action Video Games on the Spatial Distribution of Visuospatial Attention

    Science.gov (United States)

    Green, C. Shawn; Bavelier, Daphne

    2006-01-01

    The authors investigated the effect of action gaming on the spatial distribution of attention. The authors used the flanker compatibility effect to separately assess center and peripheral attentional resources in gamers versus nongamers. Gamers exhibited an enhancement in attentional resources compared with nongamers, not only in the periphery but…

  19. Tyrosine Phosphorylation of the Human Serotonin Transporter: A Role in the Transporter Stability and Function

    Science.gov (United States)

    Annamalai, Balasubramaniam; Mannangatti, Padmanabhan; Arapulisamy, Obulakshmi; Shippenberg, Toni S.; Jayanthi, Lankupalle D.

    2012-01-01

    The serotonin (5-HT) transporter (SERT) regulates serotoninergic neurotransmission by clearing 5-HT released into the synaptic space. Phosphorylation of SERT on serine and threonine mediates SERT regulation. Whether tyrosine phosphorylation regulates SERT is unknown. Here, we tested the hypothesis that tyrosine-phosphorylation of SERT regulates 5-HT transport. In support of this, alkali-resistant 32P-labeled SERT was found in rat platelets, and Src-tyrosine kinase inhibitor 4-amino-5-(4-chlorophenyl)-7-(t-butyl)pyrazolo [3,4,d]pyrimidine (PP2) decreased platelet SERT function and expression. In human placental trophoblast cells expressing SERT, PP2 reduced transporter function, expression, and stability. Although siRNA silencing of Src expression decreased SERT function and expression, coexpression of Src resulted in PP2-sensitive increases in SERT function and expression. PP2 treatment markedly decreased SERT protein stability. Compared with WT-SERT, SERT tyrosine mutants Y47F and Y142F exhibited reduced 5-HT transport despite their higher total and cell surface expression levels. Moreover, Src-coexpression increased total and cell surface expression of Y47F and Y142F SERT mutants without affecting their 5-HT transport capacity. It is noteworthy that Y47F and Y142F mutants exhibited higher protein stability compared with WT-SERT. However, similar to WT-SERT, PP2 treatment decreased the stability of Y47F and Y142F mutants. Furthermore, compared with WT-SERT, Y47F and Y142F mutants exhibited lower basal tyrosine phosphorylation and no further enhancement of tyrosine phosphorylation in response to Src coexpression. These results provide the first evidence that SERT tyrosine phosphorylation supports transporter protein stability and 5HT transport. PMID:21992875

  20. Determination of Areas Susceptible to Landsliding Using Spatial Patterns of Rainfall from Tropical Rainfall Measuring Mission Data, Rio de Janeiro, Brazil

    Directory of Open Access Journals (Sweden)

    Renato Fontes Guimarães

    2017-10-01

    Full Text Available Spatial patterns of shallow landslide initiation reflect both spatial patterns of heavy rainfall and areas susceptible to mass movements. We determine the areas most susceptible to shallow landslide occurrence through the calculation of critical soil cohesion and spatial patterns of rainfall derived from TRMM (Tropical Rainfall Measuring Mission data for Paraty County, State of Rio de Janeiro, Brazil. Our methodology involved: (a creating the digital elevation model (DEM and deriving attributes such as slope and contributing area; (b incorporating spatial patterns of rainfall derived from TRMM into the shallow slope stability model SHALSTAB; and (c quantitative assessment of the correspondence of mapped landslide scars to areas predicted to be most prone to shallow landsliding. We found that around 70% of the landslide scars occurred in less than 10% of the study area identified as potentially unstable. The greatest concentration of landslides occurred in areas where the root strength of vegetation is an important contribution to slope stability in regions of orographically-enhanced rainfall on the coastal topographic flank. This approach helps quantify landslide hazards in areas with similar geomorphological characteristics, but different spatial patterns of rainfall.

  1. Stability of nonlinear Vlasov-Poisson equilibria through spectral deformation and Fourier-Hermite expansion.

    Science.gov (United States)

    Siminos, Evangelos; Bénisti, Didier; Gremillet, Laurent

    2011-05-01

    We study the stability of spatially periodic, nonlinear Vlasov-Poisson equilibria as an eigenproblem in a Fourier-Hermite basis (in the space and velocity variables, respectively) of finite dimension, N. When the advection term in the Vlasov equation is dominant, the convergence with N of the eigenvalues is rather slow, limiting the applicability of the method. We use the method of spectral deformation introduced by Crawford and Hislop [Ann. Phys. (NY) 189, 265 (1989)] to selectively damp the continuum of neutral modes associated with the advection term, thus accelerating convergence. We validate and benchmark the performance of our method by reproducing the kinetic dispersion relation results for linear (spatially homogeneous) equilibria. Finally, we study the stability of a periodic Bernstein-Greene-Kruskal mode with multiple phase-space vortices, compare our results with numerical simulations of the Vlasov-Poisson system, and show that the initial unstable equilibrium may evolve to different asymptotic states depending on the way it was perturbed. © 2011 American Physical Society

  2. Three-dimensional stability, receptivity and sensitivity of non-Newtonian flows inside open cavities

    International Nuclear Information System (INIS)

    Citro, Vincenzo; Giannetti, Flavio; Pralits, Jan O

    2015-01-01

    We investigate the stability properties of flows over an open square cavity for fluids with shear-dependent viscosity. Analysis is carried out in context of the linear theory using a normal-mode decomposition. The incompressible Cauchy equations, with a Carreau viscosity model, are discretized with a finite-element method. The characteristics of direct and adjoint eigenmodes are analyzed and discussed in order to understand the receptivity features of the flow. Furthermore, we identify the regions of the flow that are more sensitive to spatially localized feedback by building a spatial map obtained from the product between the direct and adjoint eigenfunctions. Analysis shows that the first global linear instability of the steady flow is a steady or unsteady three-dimensionl bifurcation depending on the value of the power-law index n. The instability mechanism is always located inside the cavity and the linear stability results suggest a strong connection with the classical lid-driven cavity problem. (paper)

  3. Factors Affecting the Clinical Measurement of Visuo-Spatial Neglect

    Directory of Open Access Journals (Sweden)

    L. Pizzamiglio

    1992-01-01

    Full Text Available The present study examined a battery of tests to evaluate unilateral spatial neglect; the tests included different tasks involving several modalities of spatial exploration mapping perceptual, motor, attentional and personal or extrapersonal space dimensions. The subjects, 121 right-brain-damaged patients with unilateral neglect, were studied in seven laboratories in four European countries. Relationships among the various tests were examined by correlations, a cluster analysis and by an analysis of individual cases. Different sensitivity was found among various tests for detecting neglect performances. Both the cluster analysis and the single case analysis clearly showed a segregation between personal and extrapersonal neglect. Analysis of the large cluster, including a variety of tests of extra personal neglect, together with the study of single cases, suggests the possibility of differentiating the various manifestations of spatial neglect which can be interpreted on the basis of the descriptions of other individual cases previously reported in the literature. Finally, the present study indicated the relative stability of neglect following the acute phase and its independence from age.

  4. Coexistence of fraternity and egoism for spatial social dilemmas.

    Science.gov (United States)

    Szabó, György; Szolnoki, Attila; Czakó, Lilla

    2013-01-21

    We have studied an evolutionary game with spatially arranged players who can choose one of the two strategies (named cooperation and defection for social dilemmas) when playing with their neighbors. In addition to the application of the usual strategies in the present model the players are also characterized by one of the two extreme personal features representing the egoist or fraternal behavior. During the evolution each player can modify both her own strategy and/or personal feature via a myopic update process in order to improve her utility. The results of numerical simulations and stability analysis are summarized in phase diagrams representing a wide scale of spatially ordered distribution of strategies and personal features when varying the payoff parameters. In most of the cases only two of the four possible options prevail and may form sublattice ordered spatial structure. The evolutionary advantage of the fraternal attitude is demonstrated within a large range of payoff parameters including the region of prisoner's dilemma where egoist defectors and fraternal cooperators form a role-separating chessboard like pattern. Copyright © 2012 Elsevier Ltd. All rights reserved.

  5. Charpy impact behavior of manganese-stabilized martensitic steels

    International Nuclear Information System (INIS)

    Hu, W.L.; Gelles, D.S.

    1986-05-01

    Tests were conducted to evaluate the irradiation-induced shift in ductile-to-brittle transition behavior of two manganese stabilized martensitic steels. Miniature Charpy specimens were fabricated from two heats of steel similar in composition to HT-9 but with 0.1% C and Mn contents ranging from 3.3 to 6.6.%. The 3.3% Mn steel showed a transition temperature similar to that of HT-9 in both the unirradiated condition and in specimens irradiated to 11.3 dpa. The steel containing 6.6% Mn exhibited a higher transition temperature after irradiation than the steel containing 3.3% Mn. The upper shelf energy (USE) after irradiation for the manganese stabilized alloys was much higher than for HT-9. 6 refs., 3 figs., 2 tabs

  6. Comparison of spatially and temporally resolved diffuse transillumination measurement systems for extraction of optical properties of scattering media.

    Science.gov (United States)

    Ortiz-Rascón, E; Bruce, N C; Garduño-Mejía, J; Carrillo-Torres, R; Hernández-Paredes, J; Álvarez-Ramos, M E

    2017-11-20

    This paper discusses the main differences between two different methods for determining the optical properties of tissue optical phantoms by fitting the spatial and temporal intensity distribution functions to the diffusion approximation theory. The consistency in the values of the optical properties is verified by changing the width of the recipient containing the turbid medium; as the optical properties are an intrinsic value of the scattering medium, independently of the recipient width, the stability in these values for different widths implies a better measurement system for the acquisition of the optical properties. It is shown that the temporal fitting method presents higher stability than the spatial fitting method; this is probably due to the addition of the time of flight parameter into the diffusion theory.

  7. Increase in stability of cellulase immobilized on functionalized magnetic nanospheres

    Science.gov (United States)

    Zhang, Wenjuan; Qiu, Jianhui; Feng, Huixia; Zang, Limin; Sakai, Eiichi

    2015-02-01

    Functionalized magnetic nanospheres were prepared by co-condensation of tetraethylorthosilicate with three different amino-silanes: 3-(2-aminoethylamino propyl)-triethoxysilane (AEAPTES), 3-(2-aminoethylamino propyl)-trimethoxysilane (AEAPTMES) and 3-aminopropyltriethoxysilane (APTES). Then three functionalized magnetic nanospheres were used as supports for immobilization of cellulase. The three functionalized magnetic nanospheres with core-shell morphologies exhibited higher capacity for cellulase immobilization than unfunctionalized magnetic nanospheres. The increasing of surface charge of functionalized magnetic nanospheres leads to an enhancement of the capacity of cellulase immobilization. Particularly, AEAPTMES with methoxy groups was favored to be hydrolyzed and grafted on unfunctionalized magnetic nanospheres than the others. AEAPTMES functionalized magnetic nanospheres with the highest zeta potential (29 mV) exhibited 87% activity recovery and the maximum amount of immobilized cellulase was 112 mg/g support at concentration of initial cellulase of 8 mg/mL. Immobilized cellulase on AEAPTMES functionalized magnetic nanospheres had higher temperature stability and broader pH stability than other immobilized cellulases and free cellulase. In particular, it can be used in about 40 °C, demonstrating the potential of biofuel production using this immobilized cellulase.

  8. Designing immersion exhibits as border-crossing environments

    DEFF Research Database (Denmark)

    Mortensen, Marianne Foss

    2010-01-01

    be applied to achieve an understanding of the immersion exhibit form. The argument proceeds by demonstrating how the characteristics of immersion exhibits, and visitors to them, classify them as microcultures, and examining the implications of this for exhibit design using a hypothetical immersion exhibit...

  9. Development of novel zein-sodium caseinate nanoparticle (ZP)-stabilized emulsion films for improved water barrier properties via emulsion/solvent evaporation.

    Science.gov (United States)

    Wang, Li-Juan; Yin, Ye-Chong; Yin, Shou-Wei; Yang, Xiao-Quan; Shi, Wei-Jian; Tang, Chuan-He; Wang, Jin-Mei

    2013-11-20

    This work attempted to develop novel high barrier zein/SC nanoparticle (ZP)-stabilized emulsion films through microfluidic emulsification (ZPE films) or in combination with solvent (ethyl acetate) evaporation techniques (ZPE-EA films). Some physical properties, including tensile and optical properties, water vapor permeability (WVP), and surface hydrophobicity, as well as the microstructure of ZP-stabilized emulsion films were evaluated and compared with SC emulsion (SCE) films. The emulsion/solvent evaporation approach reduced lipid droplets of ZP-stabilized emulsions, and lipid droplets of ZP-stabilized emulsions were similar to or slightly lower than that of SC emulsions. However, ZP- and SC-stabilized emulsion films exhibited a completely different microstructure, nanoscalar lipid droplets were homogeneously distributed in the ZPE film matrix and interpenetrating protein-oil complex networks occurred within ZPE-EA films, whereas SCE films presented a heterogeneous microstructure. The different stabilization mechanisms against creaming or coalescence during film formation accounted for the preceding discrepancy of the microstructures between ZP-and SC-stabilized emulsion films. Interestingly, ZP-stabilized emulsion films exhibited a better water barrier efficiency, and the WVP values were only 40-50% of SCE films. A schematic representation for the formation of ZP-stabilized emulsion films was proposed to relate the physical performance of the films with their microstructure and to elucidate the possible forming mechanism of the films.

  10. Enhancement of the chemical stability in confined δ-Bi2O3

    DEFF Research Database (Denmark)

    Sanna, Simone; Esposito, Vincenzo; Andreasen, Jens Wenzel

    2015-01-01

    Bismuth-oxide-based materials are the building blocks for modern ferroelectrics1, multiferroics2, gas sensors3, light photocatalysts4 and fuel cells5,6. Although the cubic fluorite δ-phase of bismuth oxide (δ-Bi2O3) exhibits the highest conductivity of known solid-state oxygen ion conductors5, its...... instability prevents use at low temperature7–10. Here we demonstrate the possibility of stabilizing δ-Bi2O3 using highly coherent interfaces of alternating layers of Er2O3-stabilized δ-Bi2O3 and Gd2O3-doped CeO2. Remarkably, an exceptionally high chemical stability in reducing conditions and redox cycles...

  11. Spatial atomic layer deposition for coating flexible porous Li-ion battery electrodes

    Energy Technology Data Exchange (ETDEWEB)

    Yersak, Alexander S.; Sharma, Kashish; Wallas, Jasmine M.; Dameron, Arrelaine A.; Li, Xuemin; Yang, Yongan; Hurst, Katherine E.; Ban, Chunmei; Tenent, Robert C.; George, Steven M. [Department of Chemistry and Biochemistry, University of Colorado, Boulder, Colorado 80309 and Department of Mechanical Engineering, University of Colorado, Boulder, Colorado 80309

    2018-01-01

    Ultrathin atomic layer deposition (ALD) coatings on the electrodes of Li-ion batteries can enhance the capacity stability of the Li-ion batteries. To commercialize ALD for Li-ion battery production, spatial ALD is needed to decrease coating times and provide a coating process compatible with continuous roll-to-roll (R2R) processing. The porous electrodes of Li-ion batteries provide a special challenge because higher reactant exposures are needed for spatial ALD in porous substrates. This work utilized a modular rotating cylinder spatial ALD reactor operating at rotation speeds up to 200 revolutions/min (RPM) and substrate speeds up to 200 m/min. The conditions for spatial ALD were adjusted to coat flexible porous substrates. The reactor was initially used to characterize spatial Al2O3 and ZnO ALD on flat, flexible metalized polyethylene terephthalate foils. These studies showed that slower rotation speeds and spacers between the precursor module and the two adjacent pumping modules could significantly increase the reactant exposure. The modular rotating cylinder reactor was then used to coat flexible, model porous anodic aluminum oxide (AAO) membranes. The uniformity of the ZnO ALD coatings on the porous AAO membranes was dependent on the aspect ratio of the pores and the reactant exposures. Larger reactant exposures led to better uniformity in the pores with higher aspect ratios. The reactant exposures were increased by adding spacers between the precursor module and the two adjacent pumping modules. The modular rotating cylinder reactor was also employed for Al2O3 ALD on porous LiCoO2 (LCO) battery electrodes. Uniform Al coverages were obtained using spacers between the precursor module and the two adjacent pumping modules at rotation speeds of 25 and 50 RPM. The LCO electrodes had a thickness of ~49 um and pores with aspect ratios of ~12-25. Coin cells were then constructed using the ALD-coated LCO electrodes and were tested to determine their battery

  12. Long-term stability investigation of o/w cosmetic creams stabilized by mixed emulsifier

    Directory of Open Access Journals (Sweden)

    Đekić Ljiljana M.

    2012-01-01

    Full Text Available Polyglyceryl-3 Methylglucose Distearate (PMD, TEGO® Care 450, Evonik, Germanyis natural (vegetable, non-ionic, PEG-free emulsifier, suitable for the formulation of oil-in-water (o/w cosmetic creams and lotions. The oil phase components can be selected from mineral oils, vegetable oils and synthetic esters, which enable different variety of application profile of these emulsions. It is possible to prepare stable emulsions using low-level concentration of the PMD (2-3% if lotions contain 10-25%, and creams 20-40 % of oil phase. PMD forms liquid crystal structure in the presence of stearic acid, glyceryl stearate, fatty alcohols, or their combinations. The o/w type creams, stabilized by these mixed emulsifiers are complex, multiphase systems. The aim of this work was to formulate, prepare and investigate long-term stability of the o/w creams stabilized by mixed emulsifier polyglyceryl-3 methylglucose distearate/glyceryl stearate/stearyl alcohol, depending on concentration levels of PMD (2% or 3% and oil:water phase ratio (20:80 and 30:70. The samples were prepared using hot/hot procedure. Organoleptic inspection, centrifugation test, rheological measurements, electric conductivity and pH value measurements were performed 72 h, 1, 3, 12 and 30 months after preparation. The prepared samples were apparently white and homogenous creams. The consistency and homogeneity were preserved after centrifugation of the creams after 72 h, 1, 3, 12 and 30 months storage, and no phase separation could be detected. The pH values obtained are suitable for skin application. Conductivity values (25.2-63.7 μS cm1, 72 h after preparation were attributed to the multiple phase o/w emulsions with high percentages of fixed water. Results of the rheological measurements have shown that the investigated creams exhibited non-Newtonian thyxotropic behavior. The concentration of emulsifier PMD and oil phase content had an influence on the rheological parameters of investigated

  13. Algorithm for Stabilizing a POD-Based Dynamical System

    Science.gov (United States)

    Kalb, Virginia L.

    2010-01-01

    This algorithm provides a new way to improve the accuracy and asymptotic behavior of a low-dimensional system based on the proper orthogonal decomposition (POD). Given a data set representing the evolution of a system of partial differential equations (PDEs), such as the Navier-Stokes equations for incompressible flow, one may obtain a low-dimensional model in the form of ordinary differential equations (ODEs) that should model the dynamics of the flow. Temporal sampling of the direct numerical simulation of the PDEs produces a spatial time series. The POD extracts the temporal and spatial eigenfunctions of this data set. Truncated to retain only the most energetic modes followed by Galerkin projection of these modes onto the PDEs obtains a dynamical system of ordinary differential equations for the time-dependent behavior of the flow. In practice, the steps leading to this system of ODEs entail numerically computing first-order derivatives of the mean data field and the eigenfunctions, and the computation of many inner products. This is far from a perfect process, and often results in the lack of long-term stability of the system and incorrect asymptotic behavior of the model. This algorithm describes a new stabilization method that utilizes the temporal eigenfunctions to derive correction terms for the coefficients of the dynamical system to significantly reduce these errors.

  14. Spatial filtring and thermocouple spatial filter

    International Nuclear Information System (INIS)

    Han Bing; Tong Yunxian

    1989-12-01

    The design and study on thermocouple spatial filter have been conducted for the flow measurement of integrated reactor coolant. The fundamental principle of spatial filtring, mathematical descriptions and analyses of thermocouple spatial filter are given

  15. Natural and synthetic antioxidants: Influence on the oxidative stability of biodiesel synthesized from non-edible oil

    Energy Technology Data Exchange (ETDEWEB)

    Sarin, Amit [Department of Applied Sciences, Amritsar College of Engineering and Technology, Manawala, Amritsar-143001, Punjab (India); Singh, N.P. [Punjab Technical University, Jalandhar (India); Sarin, Rakesh; Malhotra, R.K. [Indian Oil Corporation Ltd., R and D Centre, Sector-13, Faridabad-121007 (India)

    2010-12-15

    According to the proposed National Mission on Biodiesel in India, we have undertaken studies on the oxidative stability of biodiesel synthesized from tree borne non-edible oil seeds jatropha. Neat jatropha biodiesel exhibited oxidation stability of 3.95 h and research was conducted to investigate the influence of natural and synthetic antioxidants on the oxidation stability of jatropha methyl ester. Antioxidants namely {alpha}-tocopherol, tert-butylated hydroxytoluene, tert-butylated phenol derivative, octylated butylated diphenyl amine, and tert-butylhydroxquinone were doped to improve the oxidation stability. It was found that both types of antioxidants showed beneficial effects in increasing the oxidation stability of jatropha methyl ester, but comparatively, the synthetic antioxidants were found to be more effective. (author)

  16. One stone, two birds: silica nanospheres significantly increase photocatalytic activity and colloidal stability of photocatalysts

    Science.gov (United States)

    Rasamani, Kowsalya D.; Foley, Jonathan J., IV; Sun, Yugang

    2018-03-01

    Silver-doped silver chloride [AgCl(Ag)] nanoparticles represent a unique class of visible-light-driven photocatalysts, in which the silver dopants introduce electron-abundant mid-gap energy levels to lower the bandgap of AgCl. However, free-standing AgCl(Ag) nanoparticles, particularly those with small sizes and large surface areas, exhibit low colloidal stability and low compositional stability upon exposure to light irradiation, leading to easy aggregation and conversion to metallic silver and thus a loss of photocatalytic activity. These problems could be eliminated by attaching the small AgCl(Ag) nanoparticles to the surfaces of spherical dielectric silica particles with submicrometer sizes. The high optical transparency in the visible spectral region (400-800 nm), colloidal stability, and chemical/electronic inertness displayed by the silica spheres make them ideal for supporting photocatalysts and significantly improving their stability. The spherical morphology of the dielectric silica particles can support light scattering resonances to generate significantly enhanced electric fields near the silica particle surfaces, on which the optical absorption cross-section of the AgCl(Ag) nanoparticles is dramatically increased to promote their photocatalytic activity. The hybrid silica/AgCl(Ag) structures exhibit superior photocatalytic activity and stability, suitable for supporting photocatalysis sustainably; for instance, their efficiency in the photocatalytic decomposition of methylene blue decreases by only ˜9% even after ten cycles of operation.

  17. Chromatic and Achromatic Spatial Resolution of Local Field Potentials in Awake Cortex.

    Science.gov (United States)

    Jansen, Michael; Li, Xiaobing; Lashgari, Reza; Kremkow, Jens; Bereshpolova, Yulia; Swadlow, Harvey A; Zaidi, Qasim; Alonso, Jose-Manuel

    2015-10-01

    Local field potentials (LFPs) have become an important measure of neuronal population activity in the brain and could provide robust signals to guide the implant of visual cortical prosthesis in the future. However, it remains unclear whether LFPs can detect weak cortical responses (e.g., cortical responses to equiluminant color) and whether they have enough visual spatial resolution to distinguish different chromatic and achromatic stimulus patterns. By recording from awake behaving macaques in primary visual cortex, here we demonstrate that LFPs respond robustly to pure chromatic stimuli and exhibit ∼2.5 times lower spatial resolution for chromatic than achromatic stimulus patterns, a value that resembles the ratio of achromatic/chromatic resolution measured with psychophysical experiments in humans. We also show that, although the spatial resolution of LFP decays with visual eccentricity as is also the case for single neurons, LFPs have higher spatial resolution and show weaker response suppression to low spatial frequencies than spiking multiunit activity. These results indicate that LFP recordings are an excellent approach to measure spatial resolution from local populations of neurons in visual cortex including those responsive to color. © The Author 2014. Published by Oxford University Press.

  18. An appraisal of the enzyme stability-activity trade-off.

    Science.gov (United States)

    Miller, Scott R

    2017-07-01

    A longstanding idea in evolutionary physiology is that an enzyme cannot jointly optimize performance at both high and low temperatures due to a trade-off between stability and activity. Although a stability-activity trade-off has been observed for well-characterized examples, such a trade-off is not imposed by any physical chemical constraint. To better understand the pervasiveness of this trade-off, I investigated the stability-activity relationship for comparative biochemical studies of purified orthologous enzymes identified by a literature search. The nature of this relationship varied greatly among studies. Notably, studies of enzymes with low mean synonymous nucleotide sequence divergence were less likely to exhibit the predicted negative correlation between stability and activity. Similarly, a survey of directed evolution investigations of the stability-activity relationship indicated that these traits are often uncoupled among nearly identical yet phenotypically divergent enzymes. This suggests that the presumptive trade-off often reported for investigations of enzymes with high mean sequence divergence may in some cases instead be a consequence of the degeneration over time of enzyme function in unselected environments, rather than a direct effect of thermal adaptation. The results caution against the general assertion of a stability-activity trade-off during enzyme adaptation. © 2017 The Author(s). Evolution © 2017 The Society for the Study of Evolution.

  19. Role of spatial inhomogenity in GPCR dimerisation predicted by receptor association-diffusion models

    Science.gov (United States)

    Deshpande, Sneha A.; Pawar, Aiswarya B.; Dighe, Anish; Athale, Chaitanya A.; Sengupta, Durba

    2017-06-01

    G protein-coupled receptor (GPCR) association is an emerging paradigm with far reaching implications in the regulation of signalling pathways and therapeutic interventions. Recent super resolution microscopy studies have revealed that receptor dimer steady state exhibits sub-second dynamics. In particular the GPCRs, muscarinic acetylcholine receptor M1 (M1MR) and formyl peptide receptor (FPR), have been demonstrated to exhibit a fast association/dissociation kinetics, independent of ligand binding. In this work, we have developed a spatial kinetic Monte Carlo model to investigate receptor homo-dimerisation at a single receptor resolution. Experimentally measured association/dissociation kinetic parameters and diffusion coefficients were used as inputs to the model. To test the effect of membrane spatial heterogeneity on the simulated steady state, simulations were compared to experimental statistics of dimerisation. In the simplest case the receptors are assumed to be diffusing in a spatially homogeneous environment, while spatial heterogeneity is modelled to result from crowding, membrane micro-domains and cytoskeletal compartmentalisation or ‘corrals’. We show that a simple association-diffusion model is sufficient to reproduce M1MR association statistics, but fails to reproduce FPR statistics despite comparable kinetic constants. A parameter sensitivity analysis is required to reproduce the association statistics of FPR. The model reveals the complex interplay between cytoskeletal components and their influence on receptor association kinetics within the features of the membrane landscape. These results constitute an important step towards understanding the factors modulating GPCR organisation.

  20. Exhibition

    CERN Multimedia

    Staff Association

    2017-01-01

    Sintropie Flavio Pellegrini From 13 to 24 March 2017 CERN Meyrin, Main Building Energia imprigionata - Flavio Pellegrini. The exhibition is composed by eleven wood artworks with the expression of movement as theme. The artworks are the result of harmonics math applied to sculpture. The powerful black colour is dominated by the light source, generating reflexes and modulations. The result is a continuous variation of perspective visions. The works generate, at a first approach, an emotion of mystery and incomprehension, only a deeper contemplation lets one discover entangling and mutative details, evidencing the elegance of the lines and letting the meaning emerge. For more information : staff.association@cern.ch | Tél: 022 766 37 38

  1. The Culture of Exhibitions and Conservation

    Directory of Open Access Journals (Sweden)

    Dimitrios Doumas

    2013-11-01

    Full Text Available The article reflects on temporary exhibitions from a theoretical as well as practical perspective. Regarded as a particularly effective mass-communication medium, exhibitions have a dual nature: they are scholarly undertakings, bringing off a curator’s vision and, simultaneously, they are projects with economic implications that need to be well managed and administered. The role of conservation in the making of temporary exhibitions, either in-house or touring, is here discussed in relation to how work is planned and prioritized as well as how time is managed and staff is allocated. Reference to weaknesses that lessen the crucial input of conservation in the decision-making process is also made. Much of the debate, which focuses on art exhibitions, concerns practicalities encountered in a private museum that extend from the very early stages of selecting objects for display to the mounting of an exhibition.

  2. Stability of one-step methods in transient nonlinear heat conduction

    International Nuclear Information System (INIS)

    Hughes, J.R.

    1977-01-01

    The purpose of the present work is to ascertain practical stability conditions for one-step methods commonly used in transient nonlinear heat conduction analyses. The class of problems considered is governed by a temporally continuous, spatially discrete system involving the capacity matrix C, conductivity matrix K, heat supply vector, temperature vector and time differenciation. In the linear case, in which K and C are constant, the stability behavior of one-step methods is well known. But in this paper the concepts of stability, appropriate to the nonlinear problem, are thoroughly discussed. They of course reduce to the usual stability criterion for the linear, constant coefficient case. However, for nonlinear problems there are differences and these ideas are of key importance in obtaining practical stability conditions. Of particular importance is a recent result which indicates that, in a sense, the trapezoidal and midpoint families are quivalent. Thus, stability results for one family may be translated into a result for the other. The main results obtained are summarized as follows. The stability behavior of the explicit Euler method in the nonlinear regime is analogous to that for linear problems. In particular, an a priori step size restriction may be determined for each time step. The precise time step restriction on implicit conditionally stable members of the trapezoidal and midpoint families is shown not to be determinable a priori. Of considerable practical significance, unconditionally stable members of the trapezoidal and midpoint families are identified

  3. Colour stabilities of three types of orthodontic clear aligners exposed to staining agents.

    Science.gov (United States)

    Liu, Chen-Lu; Sun, Wen-Tian; Liao, Wen; Lu, Wen-Xin; Li, Qi-Wen; Jeong, Yunho; Liu, Jun; Zhao, Zhi-He

    2016-12-16

    The aim of this study was to evaluate and compare the colour stabilities of three types of orthodontic clear aligners exposed to staining agents in vitro. Sixty clear orthodontic aligners produced by three manufacturers (Invisalign, Angelalign, and Smartee) were immersed in three staining solutions (coffee, black tea, and red wine) and one control solution (distilled water). After 12-h and 7-day immersions, the aligners were washed in an ultrasonic cleaner and measured with a colourimeter. The colour changes (ΔE*) were calculated on the basis of the Commission Internationale de I'Eclairage L*a*b* colour system (CIE L*a*b*), and the results were then converted into National Bureau of Standards (NBS) units. Fourier transformation infrared (FT-IR) spectroscopy and scanning electron microscopy (SEM) were conducted to observe the molecular and morphologic alterations to the aligner surfaces, respectively. The three types of aligners exhibited slight colour changes after 12 h of staining, with the exception of the Invisalign aligners stained with coffee. The Invisalign aligners exhibited significantly higher ΔE* values (ranging from 0.30 to 27.81) than those of the Angelalign and Smartee aligners (ΔE* values ranging from 0.33 to 1.89 and 0.32 to 1.61, respectively, Paligners did not exhibit significant chemical differences before and after the immersions. The SEM results revealed different surface alterations to the three types of aligner materials after the 7-day staining. The three types of aesthetic orthodontic appliances exhibited colour stability after the 12-h immersion, with the exception of the Invisalign aligners stained by coffee. The Invisalign aligners were more prone than the Angelalign and Smartee aligners to pigmentation. Aligner materials may be improved by considering aesthetic colour stability properties.

  4. Spatial and temporal analysis of postural control in dyslexic children.

    Science.gov (United States)

    Gouleme, Nathalie; Gerard, Christophe Loic; Bui-Quoc, Emmanuel; Bucci, Maria Pia

    2015-07-01

    The aim of this study is to examine postural control of dyslexic children using both spatial and temporal analysis. Thirty dyslexic (mean age 9.7±0.3years) and thirty non-dyslexic age-matched children participated in the study. Postural stability was evaluated using Multitest Equilibre from Framiral®. Posture was recorded in the following conditions: eyes open fixating a target (EO) and eyes closed (EC) on stable (-S-) and unstable (-U-) platforms. The findings of this study showed poor postural stability in dyslexic children with respect to the non-dyslexic children group, as demonstrated by both spatial and temporal analysis. In both groups of children postural control depends on the condition, and improves when the eyes are open on a stable platform. Dyslexic children have spectral power indices that are higher than in non-dyslexic children and they showed a shorter cancelling time. Poor postural control in dyslexic children could be due to a deficit in using sensory information most likely caused by impairment in cerebellar activity. The reliability of brain activation patterns, namely in using sensory input and cerebellar activity may explain the deficit in postural control in dyslexic children. Copyright © 2014 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

  5. Developmental Stability in Gender-Typed Preferences between Infancy and Preschool Age

    Science.gov (United States)

    Lauer, Jillian E.; Ilksoy, Sibel D.; Lourenco, Stella F.

    2018-01-01

    Infants exhibit visual preferences for gender-typed objects (e.g., dolls, toy vehicles) that parallel the gender-typed play preferences of preschool-aged children, but the developmental stability of individual differences in early emerging gender-typed preferences has not yet been characterized. In the present study, we examined the longitudinal…

  6. Spatial and temporal analyses for multiscale monitoring of landslides: Examples from Northern Ireland

    Science.gov (United States)

    Bell, Andrew; McKinley, Jennifer; Hughes, David

    2013-04-01

    Landslides in the form of debris flows, large scale rotational features and composite mudflows impact transport corridors cutting off local communities and in some instances result in loss of life. This study presents landslide monitoring methods used for predicting and characterising landslide activity along transport corridors. A variety of approaches are discussed: desk based risk assessment of slopes using Geographical Information Systems (GIS); Aerial LiDAR surveys and Terrestrial LiDAR monitoring and field instrumentation of selected sites. A GIS based case study is discussed which provides risk assessment for the potential of slope stability issues. Layers incorporated within the system include Digital Elevation Model (DEM), slope, aspect, solid and drift geology and groundwater conditions. Additional datasets include consequence of failure. These are combined within a risk model, presented as likelihoods of failure. This integrated spatial approach for slope risk assessment provides the user with a preliminary risk assessment of sites. An innovative "Flexviewer" web-based server interface allows users to view data without needing advanced GIS techniques to gather information about selected areas. On a macro landscape scale, Aerial LiDAR (ALS) surveys are used for the characterisation of landslides from the surrounding terrain. DEMs are generated along with terrain derivatives: slope, curvature and various measures of terrain roughness. Spatial analysis of terrain morphological parameters allow characterisation of slope stability issues and are used to predict areas of potential failure or recently failure terrain. On a local scale ground monitoring approaches are employed for the monitoring of changes in selected slopes using ALS and risk assessment approaches. Results are shown from on-going bimonthly Terrestrial LiDAR (TLS) monitoring of the slope within a site specific geodectically referenced network. This has allowed a classification of changes in the

  7. The evaluation of anthropogenic impact on the ecological stability of landscape.

    Science.gov (United States)

    Michaeli, Eva; Ivanová, Monika; Koco, Štefan

    2015-01-01

    The model area is the northern surrounding of the water reservoir Zemplinska Irava in the east of Slovakia. Selection of the examined territory and the time horizons was not random. The aim was to capture the intensity level of anthropogenic impact on the values of the coefficient of ecological stability after the construction of water reservoir, Zempifnska Irava. The contribution evaluates ecological stability of landscape in the years 1956 and 2009 by GIS technology, using two methods. The first method determines the rate of ecological stability of landscape on the basis of the significance of land cover classes in the regular network of squares (the real size of the square is 0.5 square km). The second method determines the ecological stability of landscape secondary on the basis of the man influence on the landscape. A comparison of two methods has been made, as well as interpretation of the output data (e.g., monitoring the impact of marginal land cover classes with the minimal surfaces in the grid of square at the fluctuation of the index of ecological stability, respectively, it considers the possibilities to streamline the research results using homogeneous spatial units) and it also allows to track the changes in the ecological stability of the landscape in chronological development.

  8. Structure, stability and behaviour of nucleic acids in ionic liquids

    Science.gov (United States)

    Tateishi-Karimata, Hisae; Sugimoto, Naoki

    2014-01-01

    Nucleic acids have become a powerful tool in nanotechnology because of their conformational polymorphism. However, lack of a medium in which nucleic acid structures exhibit long-term stability has been a bottleneck. Ionic liquids (ILs) are potential solvents in the nanotechnology field. Hydrated ILs, such as choline dihydrogen phosphate (choline dhp) and deep eutectic solvent (DES) prepared from choline chloride and urea, are ‘green’ solvents that ensure long-term stability of biomolecules. An understanding of the behaviour of nucleic acids in hydrated ILs is necessary for developing DNA materials. We here review current knowledge about the structures and stabilities of nucleic acids in choline dhp and DES. Interestingly, in choline dhp, A–T base pairs are more stable than G–C base pairs, the reverse of the situation in buffered NaCl solution. Moreover, DNA triplex formation is markedly stabilized in hydrated ILs compared with aqueous solution. In choline dhp, the stability of Hoogsteen base pairs is comparable to that of Watson–Crick base pairs. Moreover, the parallel form of the G-quadruplex is stabilized in DES compared with aqueous solution. The behaviours of various DNA molecules in ILs detailed here should be useful for designing oligonucleotides for the development of nanomaterials and nanodevices. PMID:25013178

  9. Electrochemical stability of ionic clathrate hydrates and their structural consideration

    International Nuclear Information System (INIS)

    Lee, Wonhee; Lim, Dongwook; Lee, Huen

    2013-01-01

    Although electrochemical stability is an essential factor in relation to the potential applications of ionic clathrate hydrates to solid electrolytes, most studies regarding the proton conductors have focused on their ionic conductivity and thermal stability. Solid electrolytes in various electrochemical devices have to endure the applied potentials; thus, we examined the linear sweep voltammograms of various tetraalkylammonium hydroxide hydrates in order to shed light on the trend of electrochemical stability depending on the hydrate structure. We revealed that the electrochemical stability of Me 4 NOH hydrates is mainly affected by both their ionic concentration and cage occupancy. In particular, the true clathrate structures of β-Me 4 NOH hydrates are more electrochemically stable than their α-forms that possess partially broken hydrogen bonds. We also observed that the binary THF–Pr 4 NOH and pure Bu 4 NOH clathrate hydrates exhibit greater electrochemical stability than those of pure Me 4 NOH hydrates having lower or similar ionic concentrations. These results are considered to arise from the fact that each of the Pr 4 N + and Bu 4 N + ions occupies an extended space comprising four cages, which leads to stabilization of the larger unit, whereas a Me 4 N + ion is completely included only in one cage

  10. Spatial attraction in migrants' settlement patterns in the city of Catania

    Directory of Open Access Journals (Sweden)

    Angelo Mazza

    2016-07-01

    Full Text Available Background: In broad terms, and apart from ethnic discriminatory rules enforced in some places and at some times, residential segregation may be ascribed both to economic inhomogeneities in the urban space (e.g., in the cost of rents, or in occupation opportunities and to spatial attraction among individuals sharing the same group identity and culture. Objective: Traditional indices of spatial segregation do not distinguish between these two sources of clustering. Furthermore, they typically rely on census tracts, a scale that does not allow for fine-grained analysis. Also, the use of alternative zoning often leads to conflicting results. The aim of this paper is to measure spatial attraction among groups of foreign migrants in Catania (Italy using individual household data. Methods: We apply a version of Ripley's K-function specially conceived for assessing spatial attraction while adjusting for the effects of spatial inhomogeneity. To avoid the risk of confounding the two sources of clustering, spatial inhomogeneity is estimated following a case-control approach. Results: Different parts of the city exhibit different suitabilities for migrants of different nationalities, with groups mainly involved in housekeeping and caregiving being more spread than the ones specialized in peddling and retailing. A significant spatial attraction has been found for Sri Lankan, Mauritians, Senegalese, and Chinese. Conversely, the settlement patterns of Tunisians and Moroccans comply with random allocation. These results seem consistent with the hypothesis of a relevant correlation between chain migration and spatial attraction.

  11. Stability of superconducting cables for use in large magnet systems

    International Nuclear Information System (INIS)

    Tateishi, Hiroshi; Schmidt, C.

    1992-01-01

    The construction of large superconducting magnets requires the development of complicated conductor types, which can fulfill the specific requirements of different types of magnets. A rather hard boundary condition for large magnets is the presence of fast changing magnetic fields. In the Institute of Technical Physics of the Karlsruhe Nuclear Research Center, Germany, a superconducting cable was developed for use in poloidal field coils in Tokamak experiments. This 'POLO'-cable exhibits low losses in a magnetic ac-field and a high stability margin. In the present article the requirements on a superconducting cable are described, as well as the mechanisms of ac-losses and the calculation of the stability limit. Calculated values are compared with experimental data. Some unresolved problems concerning the stability of large magnets are discussed taking the example of the POLO-cable. (author)

  12. Online Exhibits & Concept Maps

    Science.gov (United States)

    Douma, M.

    2009-12-01

    Presenting the complexity of geosciences to the public via the Internet poses a number of challenges. For example, utilizing various - and sometimes redundant - Web 2.0 tools can quickly devour limited time. Do you tweet? Do you write press releases? Do you create an exhibit or concept map? The presentation will provide participants with a context for utilizing Web 2.0 tools by briefly highlighting methods of online scientific communication across several dimensions. It will address issues of: * breadth and depth (e.g. from narrow topics to well-rounded views), * presentation methods (e.g. from text to multimedia, from momentary to enduring), * sources and audiences (e.g. for experts or for the public, content developed by producers to that developed by users), * content display (e.g. from linear to non-linear, from instructive to entertaining), * barriers to entry (e.g. from an incumbent advantage to neophyte accessible, from amateur to professional), * cost and reach (e.g. from cheap to expensive), and * impact (e.g. the amount learned, from anonymity to brand awareness). Against this backdrop, the presentation will provide an overview of two methods of online information dissemination, exhibits and concept maps, using the WebExhibits online museum (www.webexhibits.org) and SpicyNodes information visualization tool (www.spicynodes.org) as examples, with tips on how geoscientists can use either to communicate their science. Richly interactive online exhibits can serve to engage a large audience, appeal to visitors with multiple learning styles, prompt exploration and discovery, and present a topic’s breadth and depth. WebExhibits, which was among the first online museums, delivers interactive information, virtual experiments, and hands-on activities to the public. While large, multidisciplinary exhibits on topics like “Color Vision and Art” or “Calendars Through the Ages” require teams of scholars, user interface experts, professional writers and editors

  13. Affordances and distributed cognition in museum exhibitions

    DEFF Research Database (Denmark)

    Achiam, Marianne; May, Michael; Marandino, Martha

    2014-01-01

    consistent framework. Here, we invoke the notions of affordance and distributed cognition to explain in a coherent way how visitors interact with exhibits and exhibit spaces and make meaning from those interactions, and we exemplify our points using observations of twelve visitors to exhibits at a natural...... history museum. We show how differences in exhibit characteristics give rise to differences in the interpretive strategies used by visitors in their meaning-making process, and conclude by discussing how the notions of affordance and distributed cognition can be used in an exhibit design perspective....

  14. Research on spatial-variant property of bistatic ISAR imaging plane of space target

    International Nuclear Information System (INIS)

    Guo Bao-Feng; Wang Jun-Ling; Gao Mei-Guo

    2015-01-01

    The imaging plane of inverse synthetic aperture radar (ISAR) is the projection plane of the target. When taking an image using the range-Doppler theory, the imaging plane may have a spatial-variant property, which causes the change of scatter’s projection position and results in migration through resolution cells. In this study, we focus on the spatial-variant property of the imaging plane of a three-axis-stabilized space target. The innovative contributions are as follows. 1) The target motion model in orbit is provided based on a two-body model. 2) The instantaneous imaging plane is determined by the method of vector analysis. 3) Three Euler angles are introduced to describe the spatial-variant property of the imaging plane, and the image quality is analyzed. The simulation results confirm the analysis of the spatial-variant property. The research in this study is significant for the selection of the imaging segment, and provides the evidence for the following data processing and compensation algorithm. (paper)

  15. Stability of sputter deposited ZnO:Cr films against acids

    International Nuclear Information System (INIS)

    Shinoda, Makoto; Nishide, Toshikazu; Sawada, Yutaka; Hosaka, Masato; Matsumoto, Toshihiko.

    1993-01-01

    ZnO:Cr films were deposited on water-cooled soda-lime glass substrates at room temperature in an Ar atmosphere by rf magnetron sputtering of a ZnO target on which Cr chips were placed. The films exhibited extraordinary stability against acids such as HCl or HNO 3 , and also high resistivities similar to those of ZnO films. The addition of Cr suppressed the growth of ZnO grains which resulted in the formation of a dense film with a smooth surface. The stability and high resistivity displayed by the ZnO:Cr films can be attributed to the formation of a chromium-oxide-rich grain boundary. (author)

  16. Holland at CERN – Industrial exhibition

    CERN Multimedia

    GS Department

    2010-01-01

    Sponsored by EVD, an agency of the Dutch Ministry of the Economy From 8 to 11 November 2010 Industrial Exhibition Administration Building Bldg. 61 9-00 - 17-30 Twenty seven companies will present their latest technology at the industrial exhibition "Holland at CERN". Dutch industry will exhibit products and technologies which are related to the field of particle physics. Individual interviews will take place directly at the stands in the Main Building. The firms will contact relevant users/technicians but any user wishing to make contact with a particular firm is welcome to use the contact details which are available from each departmental secretariat or at the following URL: http://gs-dep.web.cern.ch/gs-dep/groups/sem/ls/Industrial_Exhibitions.htm#Industrial_exhibitions You will find the list of exhibitors below. LIST OF EXHIBITORS: Schelde Exotech Vernooy BV Triumph Group INCAA Computers DeMaCo Holland bv TNO Science & Industry Janssen Precision Engi...

  17. Superconductive microstrip exhibiting negative differential resistivity

    International Nuclear Information System (INIS)

    Huebener, R.P.; Gallus, D.E.

    1975-01-01

    A device capable of exhibiting negative differential electrical resistivity over a range of values of current and voltage is formed by vapor-depositing a thin layer of a material capable of exhibiting superconductivity on an insulating substrate, establishing electrical connections at opposite ends of the deposited strip, and cooling the alloy into its superconducting range. The device will exhibit negative differential resistivity when biased in the current-induced resistive state

  18. Visual areas become less engaged in associative recall following memory stabilization.

    Science.gov (United States)

    Nieuwenhuis, Ingrid L C; Takashima, Atsuko; Oostenveld, Robert; Fernández, Guillén; Jensen, Ole

    2008-04-15

    Numerous studies have focused on changes in the activity in the hippocampus and higher association areas with consolidation and memory stabilization. Even though perceptual areas are engaged in memory recall, little is known about how memory stabilization is reflected in those areas. Using magnetoencephalography (MEG) we investigated changes in visual areas with memory stabilization. Subjects were trained on associating a face to one of eight locations. The first set of associations ('stabilized') was learned in three sessions distributed over a week. The second set ('labile') was learned in one session just prior to the MEG measurement. In the recall session only the face was presented and subjects had to indicate the correct location using a joystick. The MEG data revealed robust gamma activity during recall, which started in early visual cortex and propagated to higher visual and parietal brain areas. The occipital gamma power was higher for the labile than the stabilized condition (time=0.65-0.9 s). Also the event-related field strength was higher during recall of labile than stabilized associations (time=0.59-1.5 s). We propose that recall of the spatial associations prior to memory stabilization involves a top-down process relying on reconstructing learned representations in visual areas. This process is reflected in gamma band activity consistent with the notion that neuronal synchronization in the gamma band is required for visual representations. More direct synaptic connections are formed with memory stabilization, thus decreasing the dependence on visual areas.

  19. Dry limit to photosynthesis and cyanobacterial spatial pattern in the Atacama Desert

    Science.gov (United States)

    Warren-Rhodes, K. A.; Pointing, S. B.; Ewing, S.; Lacap, D.; Gomez-Silva, B.; Amundson, R.; Friedmann, E. I.; McKay, C. P.

    2005-12-01

    Hypolithic autotrophs inhabit translucent rocks in the world`'s most extreme hot and cold deserts. Across a rainfall gradient in the Atacama, we measured a three-fold decline in the molecular diversity of cyanobacterial communities and a drop in their abundance from 28% in relatively wet sites to 0.08% in the driest core. Like plants, hypoliths appear to exhibit traits of self-organized patchiness (aggregated spatial patterns) that tightly correlate with rainfall. Rare cyanobacteria in the core live slowly (3,200 y turnover times) and survive in spatially isolated patches of self-augmented fertility, with the dry limit to their survival occurring at ~Mars but may have existed in rare oases in the past. The spatial distributions of terrestrial desert microbes should be considered in the remote search for life on Mars.

  20. A versatile synthesis of highly bactericidal Myramistin (registered) stabilized silver nanoparticles

    International Nuclear Information System (INIS)

    Vertelov, G K; Krutyakov, Yu A; Olenin, A Yu; Lisichkin, G V; Efremenkova, O V

    2008-01-01

    Silver nanoparticles stabilized by a well-known antibacterial surfactant benzyldimethyl[3-(myristoylamino)propyl]ammonium chloride (Myramistin) were produced for the first time by borohydride reduction of silver chloride sol in water. Stable aqueous dispersions of silver nanoparticles without evident precipitation for several months could be obtained. In vitro bactericidal tests showed that Myramistin capped silver NPs exhibited notable activity against six different microorganisms-gram-positive and gram-negative bacteria, yeasts and fungi. The activity was up to 20 times higher (against E. coli) compared to Myramistin at the same concentrations and on average 2 times higher if compared with citrate-stabilized NPs

  1. Temporal and spatial influences incur reconfiguration of Arctic heathland soil bacterial community structure.

    Science.gov (United States)

    Hill, Richard; Saetnan, Eli R; Scullion, John; Gwynn-Jones, Dylan; Ostle, Nick; Edwards, Arwyn

    2016-06-01

    Microbial responses to Arctic climate change could radically alter the stability of major stores of soil carbon. However, the sensitivity of plot-scale experiments simulating climate change effects on Arctic heathland soils to potential confounding effects of spatial and temporal changes in soil microbial communities is unknown. Here, the variation in heathland soil bacterial communities at two survey sites in Sweden between spring and summer 2013 and at scales between 0-1 m and, 1-100 m and between sites (> 100 m) were investigated in parallel using 16S rRNA gene T-RFLP and amplicon sequencing. T-RFLP did not reveal spatial structuring of communities at scales structuring effects may not confound comparison between plot-scale treatments, temporal change is a significant influence. Moreover, the prominence of two temporally exclusive keystone taxa suggests that the stability of Arctic heathland soil bacterial communities could be disproportionally influenced by seasonal perturbations affecting individual taxa. © 2015 Society for Applied Microbiology and John Wiley & Sons Ltd.

  2. Spatial conditions - the 3. supervisor in project organized teaching?

    DEFF Research Database (Denmark)

    Bering Keiding, Tina

    through reflection of its own border: is this new issue inside or outside the project. Individual rooms make it easier for the project to stabilize around its eigenvalues, but also enhance the risk of cognitive jog-trot. The challenge in this case becomes to seek out disturbances which can initiate new......The contribution presents a pilot study on project work situated in different spatial contexts. The main question for the study is if and how spatial conditions influence the interaction within and between projects. Possible answers to the question are sought through observations, informal...... interviews and questionnaires. The empirical findings are reflected in a Luhmann-based re-description of project organized group based teaching (Keiding 2008). Preliminary conclusions indicate that one big difference between open-space studio and individual group rooms is related to the immediate public...

  3. Electrical conductivity and chemical stability of BaCe0· 8− xAxGd0 ...

    Indian Academy of Sciences (India)

    ... K. BaCe0.7In0.1Gd0.2O3− and BaCe0.7Zr0.1Gd0.2O3− ceramics exhibit an excellent chemical stability against boiling water. Indium is a suitable doping element to promote the sintering densification and to enhance both electrical conductivity and chemical stability of Gd-doped BaCeO3 at operating temperatures.

  4. Thermal stability of DNA quadruplex-duplex hybrids.

    Science.gov (United States)

    Lim, Kah Wai; Khong, Zi Jian; Phan, Anh Tuân

    2014-01-14

    DNA has the capacity to adopt several distinct structural forms, such as duplex and quadruplex helices, which have been implicated in cellular processes and shown to exhibit important functional properties. Quadruplex-duplex hybrids, generated from the juxtaposition of these two structural elements, could find applications in therapeutics and nanotechnology. Here we used NMR and CD spectroscopy to investigate the thermal stability of two classes of quadruplex-duplex hybrids comprising fundamentally distinct modes of duplex and quadruplex connectivity: Construct I involves the coaxial orientation of the duplex and quadruplex helices with continual base stacking across the two components; Construct II involves the orthogonal orientation of the duplex and quadruplex helices with no base stacking between the two components. We have found that for both constructs, the stability of the quadruplex generally increases with the length of the stem-loop incorporated, with respect to quadruplexes comprising nonstructured loops of the same length, which showed a continuous drop in stability with increasing loop length. The stability of these complexes, particularly Construct I, can be substantially influenced by the base-pair steps proximal to the quadruplex-duplex junction. Bulges at the junction are largely detrimental to the adoption of the desired G-quadruplex topology for Construct I but not for Construct II. These findings should facilitate future design and prediction of quadruplex-duplex hybrids.

  5. Stability analysis and trend study of a balloon tethered in a wind, with experimental comparisons

    Science.gov (United States)

    Redd, L. T.; Bland, S. R.; Bennett, R. M.

    1973-01-01

    A stability analysis and trend study for a balloon tethered in a steady wind are presented. The linearized, stability-derivative type analysis includes balloon aerodynamics, buoyancy, mass (including apparent mass), and static forces resulting from the tether cable. The analysis has been applied to a balloon 7.64 m in length, and the results are compared with those from tow tests of this balloon. This comparison shows that the analysis gives reasonable predictions for the damping, frequencies, modes of motion, and stability boundaries exhibited by the balloon. A trend study for the 7.64-m balloon was made to illustrate how the stability boundaries are affected by changes in individual stability parameters. The trends indicated in this study may also be applicable to many other tethered-balloon systems.

  6. Spatial Harmonic Decomposition as a tool for unsteady flow phenomena analysis

    International Nuclear Information System (INIS)

    Duparchy, A; Guillozet, J; De Colombel, T; Bornard, L

    2014-01-01

    Hydropower is already the largest single renewable electricity source today but its further development will face new deployment constraints such as large-scale projects in emerging economies and the growth of intermittent renewable energy technologies. The potential role of hydropower as a grid stabilizer leads to operating hydro power plants in ''off-design'' zones. As a result, new methods of analyzing associated unsteady phenomena are needed to improve the design of hydraulic turbines. The key idea of the development is to compute a spatial description of a phenomenon by using a combination from several sensor signals. The spatial harmonic decomposition (SHD) extends the concept of so-called synchronous and asynchronous pulsations by projecting sensor signals on a linearly independent set of a modal scheme. This mathematical approach is very generic as it can be applied on any linear distribution of a scalar quantity defined on a closed curve. After a mathematical description of SHD, this paper will discuss the impact of instrumentation and provide tools to understand SHD signals. Then, as an example of a practical application, SHD is applied on a model test measurement in order to capture and describe dynamic pressure fields. Particularly, the spatial description of the phenomena provides new tools to separate the part of pressure fluctuations that contribute to output power instability or mechanical stresses. The study of the machine stability in partial load operating range in turbine mode or the comparison between the gap pressure field and radial thrust behavior during turbine brake operation are both relevant illustrations of SHD contribution

  7. Spatial Impairment and Memory in Genetic Disorders: Insights from Mouse Models

    Directory of Open Access Journals (Sweden)

    Sang Ah Lee

    2017-02-01

    Full Text Available Research across the cognitive and brain sciences has begun to elucidate some of the processes that guide navigation and spatial memory. Boundary geometry and featural landmarks are two distinct classes of environmental cues that have dissociable neural correlates in spatial representation and follow different patterns of learning. Consequently, spatial navigation depends both on the type of cue available and on the type of learning provided. We investigated this interaction between spatial representation and memory by administering two different tasks (working memory, reference memory using two different environmental cues (rectangular geometry, striped landmark in mouse models of human genetic disorders: Prader-Willi syndrome (PWScrm+/p− mice, n = 12 and Beta-catenin mutation (Thr653Lys-substituted mice, n = 12. This exploratory study provides suggestive evidence that these models exhibit different abilities and impairments in navigating by boundary geometry and featural landmarks, depending on the type of memory task administered. We discuss these data in light of the specific deficits in cognitive and brain function in these human syndromes and their animal model counterparts.

  8. Spatial-temporal variability of leaf chlorophyll and its relationship with cocoa yield

    Directory of Open Access Journals (Sweden)

    Caique C. Medauar

    Full Text Available ABSTRACT The objective of this study was to evaluate the spatial-temporal variability of leaf chlorophyll index and its relationship with cocoa yield. The experiment was carried out in an experimental area of cocoa production located in Ilhéus, Bahia State, Brazil. Leaf chlorophyll content was measured in September, October, January, February, March and April in the 2014/2015 season, at each sampling point of a regular grid by using a portable chlorophyll meter. Under the same conditions, yield was evaluated and the data were submitted to descriptive statistics and a linear correlation study. Geostatistical analysis was used to determine and quantify the spatial and temporal variability of leaf chlorophyll index and yield. Leaf chlorophyll index varied over the period evaluated, but the months of February, March and April showed no spatial dependence in the study area, indicating absence of temporal stability. Cocoa monthly yield, except in January, presented high spatial variability. Under the conditions of this study, it was not possible to establish a relationship between leaf chlorophyll index and cocoa yield.

  9. Eco-evolutionary spatial dynamics in the Glanville fritillary butterfly.

    Science.gov (United States)

    Hanski, Ilkka A

    2011-08-30

    Demographic population dynamics, gene flow, and local adaptation may influence each other and lead to coupling of ecological and evolutionary dynamics, especially in species inhabiting fragmented heterogeneous environments. Here, I review long-term research on eco-evolutionary spatial dynamics in the Glanville fritillary butterfly inhabiting a large network of approximately 4,000 meadows in Finland. The metapopulation persists in a balance between frequent local extinctions and recolonizations. The genetic spatial structure as defined by neutral markers is much more coarse-grained than the demographic spatial structure determined by the fragmented habitat, yet small-scale spatial structure has important consequences for the dynamics. I discuss three examples of eco-evolutionary spatial dynamics. (i) Extinction-colonization metapopulation dynamics influence allele frequency changes in the phosphoglucose isomerase (Pgi) gene, which leads to strong associations between genetic variation in Pgi and dispersal, recolonization, and local population dynamics. (ii) Inbreeding in local populations increases their risk for extinction, whereas reciprocal effects between inbreeding, population size, and emigration represent likely eco-evolutionary feedbacks. (iii) Genetically determined female oviposition preference for two host plant species exhibits a cline paralleling a gradient in host plant relative abundances, and host plant preference of dispersing females in relation to the host plant composition of habitat patches influences immigration (gene flow) and recolonization (founder events). Eco-evolutionary spatial dynamics in heterogeneous environments may not lead to directional evolutionary changes unless the environment itself changes, but eco-evolutionary dynamics may contribute to the maintenance of genetic variation attributable to fluctuating selection in space and time.

  10. Feedback stabilization of electrostatic reactive instabilities

    International Nuclear Information System (INIS)

    Richards, R.K.

    1976-01-01

    A general theory for the feedback stabilization of electrostatic reactive instabilities is developed which includes the effects of dissipation in the plasma and frequency dependence in the sensor-suppressor elements and in the external feedback circuit. This theory is compared to experiments involving particular reactive instability, an interchange mode, found in a magnetic mirror device; these results are found to be in good agreement with theory. One noteworthy result is that a frequency dependence in the overall gain and phase shift of the feedback loop can cause destabilization at large gain. Multimode feedback stabilization is studied using the spatial variation of two interchange modes to separate them such that each can be acted upon individually by the feedback system. The transfer function of the plasma is also examined. This analysis is used for mode identification and location of the pole positions. As an example of using feedback as a diagnostic tool, instability induced transport is studied. Here feedback is used to control the amplitude of fluctuations at saturation

  11. Spatial Clockwork Recurrent Neural Network for Muscle Perimysium Segmentation.

    Science.gov (United States)

    Xie, Yuanpu; Zhang, Zizhao; Sapkota, Manish; Yang, Lin

    2016-10-01

    Accurate segmentation of perimysium plays an important role in early diagnosis of many muscle diseases because many diseases contain different perimysium inflammation. However, it remains as a challenging task due to the complex appearance of the perymisum morphology and its ambiguity to the background area. The muscle perimysium also exhibits strong structure spanned in the entire tissue, which makes it difficult for current local patch-based methods to capture this long-range context information. In this paper, we propose a novel spatial clockwork recurrent neural network (spatial CW-RNN) to address those issues. Specifically, we split the entire image into a set of non-overlapping image patches, and the semantic dependencies among them are modeled by the proposed spatial CW-RNN. Our method directly takes the 2D structure of the image into consideration and is capable of encoding the context information of the entire image into the local representation of each patch. Meanwhile, we leverage on the structured regression to assign one prediction mask rather than a single class label to each local patch, which enables both efficient training and testing. We extensively test our method for perimysium segmentation using digitized muscle microscopy images. Experimental results demonstrate the superiority of the novel spatial CW-RNN over other existing state of the arts.

  12. Spatial segregation in eastern North Pacific skate assemblages.

    Directory of Open Access Journals (Sweden)

    Joseph J Bizzarro

    Full Text Available Skates (Rajiformes: Rajoidei are common mesopredators in marine benthic communities. The spatial associations of individual species and the structure of assemblages are of considerable importance for effective monitoring and management of exploited skate populations. This study investigated the spatial associations of eastern North Pacific (ENP skates in continental shelf and upper continental slope waters of two regions: central California and the western Gulf of Alaska. Long-term survey data were analyzed using GIS/spatial analysis techniques and regression models to determine distribution (by depth, temperature, and latitude/longitude and relative abundance of the dominant species in each region. Submersible video data were incorporated for California to facilitate habitat association analysis. We addressed three main questions: 1 Are there regions of differential importance to skates?, 2 Are ENP skate assemblages spatially segregated?, and 3 When skates co-occur, do they differ in size? Skate populations were highly clustered in both regions, on scales of 10s of kilometers; however, high-density regions (i.e., hot spots were segregated among species. Skate densities and frequencies of occurrence were substantially lower in Alaska as compared to California. Although skates are generally found on soft sediment habitats, Raja rhina exhibited the strongest association with mixed substrates, and R. stellulata catches were greatest on rocky reefs. Size segregation was evident in regions where species overlapped substantially in geographic and depth distribution (e.g., R. rhina and Bathyraja kincaidii off California; B. aleutica and B. interrupta in the Gulf of Alaska. Spatial niche differentiation in skates appears to be more pronounced than previously reported.

  13. Spatial segregation in eastern North Pacific skate assemblages.

    Science.gov (United States)

    Bizzarro, Joseph J; Broms, Kristin M; Logsdon, Miles G; Ebert, David A; Yoklavich, Mary M; Kuhnz, Linda A; Summers, Adam P

    2014-01-01

    Skates (Rajiformes: Rajoidei) are common mesopredators in marine benthic communities. The spatial associations of individual species and the structure of assemblages are of considerable importance for effective monitoring and management of exploited skate populations. This study investigated the spatial associations of eastern North Pacific (ENP) skates in continental shelf and upper continental slope waters of two regions: central California and the western Gulf of Alaska. Long-term survey data were analyzed using GIS/spatial analysis techniques and regression models to determine distribution (by depth, temperature, and latitude/longitude) and relative abundance of the dominant species in each region. Submersible video data were incorporated for California to facilitate habitat association analysis. We addressed three main questions: 1) Are there regions of differential importance to skates?, 2) Are ENP skate assemblages spatially segregated?, and 3) When skates co-occur, do they differ in size? Skate populations were highly clustered in both regions, on scales of 10s of kilometers; however, high-density regions (i.e., hot spots) were segregated among species. Skate densities and frequencies of occurrence were substantially lower in Alaska as compared to California. Although skates are generally found on soft sediment habitats, Raja rhina exhibited the strongest association with mixed substrates, and R. stellulata catches were greatest on rocky reefs. Size segregation was evident in regions where species overlapped substantially in geographic and depth distribution (e.g., R. rhina and Bathyraja kincaidii off California; B. aleutica and B. interrupta in the Gulf of Alaska). Spatial niche differentiation in skates appears to be more pronounced than previously reported.

  14. Yield performance and stability of CMS-based triticale hybrids.

    Science.gov (United States)

    Mühleisen, Jonathan; Piepho, Hans-Peter; Maurer, Hans Peter; Reif, Jochen Christoph

    2015-02-01

    CMS-based triticale hybrids showed only marginal midparent heterosis for grain yield and lower dynamic yield stability compared to inbred lines. Hybrids of triticale (×Triticosecale Wittmack) are expected to possess outstanding yield performance and increased dynamic yield stability. The objectives of the present study were to (1) examine the optimum choice of the biometrical model to compare yield stability of hybrids versus lines, (2) investigate whether hybrids exhibit a more pronounced grain yield performance and yield stability, and (3) study optimal strategies to predict yield stability of hybrids. Thirteen female and seven male parental lines and their 91 factorial hybrids as well as 30 commercial lines were evaluated for grain yield in up to 20 environments. Hybrids were produced using a cytoplasmic male sterility (CMS)-inducing cytoplasm that originated from Triticumtimopheevii Zhuk. We found that the choice of the biometrical model can cause contrasting results and concluded that a group-by-environment interaction term should be added to the model when estimating stability variance of hybrids and lines. midparent heterosis for grain yield was on average 3 % with a range from -15.0 to 11.5 %. No hybrid outperformed the best inbred line. Hybrids had, on average, lower dynamic yield stability compared to the inbred lines. Grain yield performance of hybrids could be predicted based on midparent values and general combining ability (GCA)-predicted values. In contrast, stability variance of hybrids could be predicted only based on GCA-predicted values. We speculated that negative effects of the used CMS cytoplasm might be the reason for the low performance and yield stability of the hybrids. For this purpose a detailed study on the reasons for the drawback of the currently existing CMS system in triticale is urgently required comprising also the search of potentially alternative hybridization systems.

  15. Trapped particle stability for the kinetic stabilizer

    Science.gov (United States)

    Berk, H. L.; Pratt, J.

    2011-08-01

    A kinetically stabilized axially symmetric tandem mirror (KSTM) uses the momentum flux of low-energy, unconfined particles that sample only the outer end-regions of the mirror plugs, where large favourable field-line curvature exists. The window of operation is determined for achieving magnetohydrodynamic (MHD) stability with tolerable energy drain from the kinetic stabilizer. Then MHD stable systems are analysed for stability of the trapped particle mode. This mode is characterized by the detachment of the central-cell plasma from the kinetic-stabilizer region without inducing field-line bending. Stability of the trapped particle mode is sensitive to the electron connection between the stabilizer and the end plug. It is found that the stability condition for the trapped particle mode is more constraining than the stability condition for the MHD mode, and it is challenging to satisfy the required power constraint. Furthermore, a severe power drain may arise from the necessary connection of low-energy electrons in the kinetic stabilizer to the central region.

  16. Multi-armed spirals and multi-pairs antispirals in spatial rock–paper–scissors games

    Energy Technology Data Exchange (ETDEWEB)

    Jiang, Luo-Luo, E-mail: jiangluoluo@gmail.com [College of Physics and Electronic Information Engineering, Wenzhou University, Wenzhou 325035 (China); College of Physics and Technology, Guangxi Normal University, Guilin, Guangxi 541004 (China); Wang, Wen-Xu [School of Electrical, Computer and Energy Engineering, Arizona State University, Tempe, AZ 85287 (United States); Department of Physics, Beijing Normal University, Beijing 100875 (China); Lai, Ying-Cheng [School of Electrical, Computer and Energy Engineering, Arizona State University, Tempe, AZ 85287 (United States); Department of Physics, Arizona State University, Tempe, AZ 85287 (United States); Ni, Xuan [School of Electrical, Computer and Energy Engineering, Arizona State University, Tempe, AZ 85287 (United States)

    2012-07-09

    We study the formation of multi-armed spirals and multi-pairs antispirals in spatial rock–paper–scissors games with mobile individuals. We discover a set of seed distributions of species, which is able to produce multi-armed spirals and multi-pairs antispirals with a finite number of arms and pairs based on stochastic processes. The joint spiral waves are also predicted by a theoretical model based on partial differential equations associated with specific initial conditions. The spatial entropy of patterns is introduced to differentiate the multi-armed spirals and multi-pairs antispirals. For the given mobility, the spatial entropy of multi-armed spirals is higher than that of single armed spirals. The stability of the waves is explored with respect to individual mobility. Particularly, we find that both two armed spirals and one pair antispirals transform to the single armed spirals. Furthermore, multi-armed spirals and multi-pairs antispirals are relatively stable for intermediate mobility. The joint spirals with lower numbers of arms and pairs are relatively more stable than those with higher numbers of arms and pairs. In addition, comparing to large amount of previous work, we employ the no flux boundary conditions which enables quantitative studies of pattern formation and stability in the system of stochastic interactions in the absence of excitable media. -- Highlights: ► Multi-armed spirals and multi-pairs antispirals are observed. ► Patterns are predicted by computer simulations and partial differential equations. ► The spatial entropy of patterns is introduced. ► Patterns are relatively stable for intermediate mobility. ► The joint spirals with lower numbers of arms and pairs are relatively more stable.

  17. Multi-armed spirals and multi-pairs antispirals in spatial rock–paper–scissors games

    International Nuclear Information System (INIS)

    Jiang, Luo-Luo; Wang, Wen-Xu; Lai, Ying-Cheng; Ni, Xuan

    2012-01-01

    We study the formation of multi-armed spirals and multi-pairs antispirals in spatial rock–paper–scissors games with mobile individuals. We discover a set of seed distributions of species, which is able to produce multi-armed spirals and multi-pairs antispirals with a finite number of arms and pairs based on stochastic processes. The joint spiral waves are also predicted by a theoretical model based on partial differential equations associated with specific initial conditions. The spatial entropy of patterns is introduced to differentiate the multi-armed spirals and multi-pairs antispirals. For the given mobility, the spatial entropy of multi-armed spirals is higher than that of single armed spirals. The stability of the waves is explored with respect to individual mobility. Particularly, we find that both two armed spirals and one pair antispirals transform to the single armed spirals. Furthermore, multi-armed spirals and multi-pairs antispirals are relatively stable for intermediate mobility. The joint spirals with lower numbers of arms and pairs are relatively more stable than those with higher numbers of arms and pairs. In addition, comparing to large amount of previous work, we employ the no flux boundary conditions which enables quantitative studies of pattern formation and stability in the system of stochastic interactions in the absence of excitable media. -- Highlights: ► Multi-armed spirals and multi-pairs antispirals are observed. ► Patterns are predicted by computer simulations and partial differential equations. ► The spatial entropy of patterns is introduced. ► Patterns are relatively stable for intermediate mobility. ► The joint spirals with lower numbers of arms and pairs are relatively more stable.

  18. The extreme vulnerability of interdependent spatially embedded networks

    Science.gov (United States)

    Bashan, Amir; Berezin, Yehiel; Buldyrev, Sergey V.; Havlin, Shlomo

    2013-10-01

    Recent studies show that in interdependent networks a very small failure in one network may lead to catastrophic consequences. Above a critical fraction of interdependent nodes, even a single node failure can invoke cascading failures that may abruptly fragment the system, whereas below this critical dependency a failure of a few nodes leads only to a small amount of damage to the system. So far, research has focused on interdependent random networks without space limitations. However, many real systems, such as power grids and the Internet, are not random but are spatially embedded. Here we analytically and numerically study the stability of interdependent spatially embedded networks modelled as lattice networks. Surprisingly, we find that in lattice systems, in contrast to non-embedded systems, there is no critical dependency and any small fraction of interdependent nodes leads to an abrupt collapse. We show that this extreme vulnerability of very weakly coupled lattices is a consequence of the critical exponent describing the percolation transition of a single lattice.

  19. Stabilization of nonlinear excitations by disorder

    DEFF Research Database (Denmark)

    Christiansen, Peter Leth; Gaididei, Yuri Borisovich; Johansson, M.

    1998-01-01

    Using analytical and numerical techniques we analyze the static and dynamical properties of solitonlike excitations in the presence of parametric disorder in the one-dimensional nonlinear Schrodinger equation with a homogeneous power nonlinearity. Both the continuum and the discrete problem...... are investigated. We find that otherwise unstable excitations can be stabilized by the presence of disorder in the continuum problem. For the very narrow excitations of the discrete problem we find that the disorder has no effect on the averaged behavior. Finally, we show that the disorder can be applied to induce...... a high degree of controllability of the spatial extent of the stable excitations in the continuum system....

  20. Socioeconomic Drivers of Environmental Pollution in China: A Spatial Econometric Analysis

    Directory of Open Access Journals (Sweden)

    Jianmin Liu

    2017-01-01

    Full Text Available This paper studies the environmental pollution and its impacts in China using prefecture-level cities and municipalities data. Moran’s I, the widely used spatial autocorrelation index, provides a fairly strong pattern of spatial clustering of environmental pollution and suggests a fairly high stability of the positive spatial correlation. To investigate the driving forces of environmental pollution and explore the relationship between fiscal decentralization, economic growth, and environmental pollution, spatial Durbin model is used for this analysis. The result shows that fiscal decentralization of local unit plays a significant role in promoting the environmental pollution and the feedback effect of fiscal decentralization on environmental pollution is also positive, though it is not significant. The relationship of GDP per capita and environmental pollution shows inverted U-shaped curve. Due to the scale effect of secondary industry, the higher the level of secondary industry development in a unit is, the easier it is to attract the secondary industry in adjacent units, which mitigates the environmental pollution in adjacent units. Densely populated areas tend to deteriorate local environment, but environmental regulation in densely populated areas is often tighter than other areas, which reduces environmental pollution to a certain extent.

  1. Active stabilization of a Michelson interferometer at an arbitrary phase with subnanometer resolution.

    Science.gov (United States)

    Grassani, Davide; Galli, Matteo; Bajoni, Daniele

    2014-04-15

    We report on the active stabilization of a Michelson interferometer at an arbitrary phase angle with a precision better than 1° at λ=632.8  nm, which corresponds to a precision in the optical path difference between the two arms of less than 1 nm. The stabilization method is ditherless, and the error signal is computed from the spatial shift of the interference pattern of a reference laser, measured in real-time with a CCD array detector. We discuss the usefulness of this method for nanopositioning, optical interferometry, and quantum optical experiments.

  2. Freeze-dried snake antivenoms formulated with sorbitol, sucrose or mannitol: comparison of their stability in an accelerated test.

    Science.gov (United States)

    Herrera, María; Tattini, Virgilio; Pitombo, Ronaldo N M; Gutiérrez, José María; Borgognoni, Camila; Vega-Baudrit, José; Solera, Federico; Cerdas, Maykel; Segura, Alvaro; Villalta, Mauren; Vargas, Mariángela; León, Guillermo

    2014-11-01

    Freeze-drying is used to improve the long term stability of pharmaceutical proteins. Sugars and polyols have been successfully used in the stabilization of proteins. However, their use in the development of freeze-dried antivenoms has not been documented. In this work, whole IgG snake antivenom, purified from equine plasma, was formulated with different concentrations of sorbitol, sucrose or mannitol. The glass transition temperatures of frozen formulations, determined by Differential Scanning Calorimetry (DSC), ranged between -13.5 °C and -41 °C. In order to evaluate the effectiveness of the different stabilizers, the freeze-dried samples were subjected to an accelerated stability test at 40 ± 2 °C and 75 ± 5% relative humidity. After six months of storage at 40 °C, all the formulations presented the same residual humidity, but significant differences were observed in turbidity, reconstitution time and electrophoretic pattern. Moreover, all formulations, except antivenoms freeze-dried with mannitol, exhibited the same potency for the neutralization of lethal effect of Bothrops asper venom. The 5% (w:v) sucrose formulation exhibited the best stability among the samples tested, while mannitol and sorbitol formulations turned brown. These results suggest that sucrose is a better stabilizer than mannitol and sorbitol in the formulation of freeze-dried antivenoms under the studied conditions. Copyright © 2014 Elsevier Ltd. All rights reserved.

  3. Spatial orientation and postural control in patients with Parkinson's disease.

    Science.gov (United States)

    Pawlitzki, E; Schlenstedt, C; Schmidt, N; Rotkirch, I; Gövert, F; Hartwigsen, G; Witt, K

    2018-02-01

    Postural instability is one of the most disabling and risky symptoms of advanced Parkinson's disease (PD). The purpose of this study was to investigate whether and how this is mediated by a centrally impaired spatial orientation. Therefore, we performed a spatial orientation study in 21 PD patients (mean age 68years, SD 8.5 years, 9 women) in a medically on condition and 21 healthy controls (mean age 68.9years, SD 5.5years, 14 women). We compared their spatial responses to the horizontal axis (Sakashita's visual target cancellation task), the vertical axis (bucket-test), the sagittal axis (tilt table test) and postural stability using the Fullerton Advanced Balance Scale (FAB). We found larger deviations on the vertical axis in PD patients, although the direct comparisons of performance in PD patients and healthy controls did not reveal significant differences. While the total scores of the FAB Scale were significantly worse in PD (25.9 points, SD 7.2 points) compared to controls (35.1 points, SD 2.3 points, pbalance control. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. Stability measurements on cored cables in normal and superfluid helium

    International Nuclear Information System (INIS)

    GHOSH, A.K.; SAMPSON, W.B.; KIM, S.W.; LEROY, D.; OBERLI, L.R.; WILSON, M.N.

    1998-01-01

    The relative stability of LHC type cables has been measured by the direct heating of one of the individual strands with a short duration current pulse. The minimum energy required to initiate a quench has been determined for a number of cables which have a central core to increase the effective inter-strand cross-over resistance. Experiments were performed in both normal helium at 4.4 K and superfluid at 1.9 K. Conductors in general are less stable at the lower temperature when measured at the same fraction of critical current. Results show that the cored-cables, even when partially filled with solder or with a porous-metal filler exhibit a relatively low stability at currents close to the critical current. It is speculated that the high inter-strand electrical and thermal resistance inherent in these cables may effect the stability at high currents

  5. Students-exhibits interaction at a science center

    Science.gov (United States)

    Botelho, Agostinho; Morais, Ana M.

    2006-12-01

    In this study we investigate students' learning during their interaction with two exhibits at a science center. Specifically, we analyze both students' procedures when interacting with exhibits and their understanding of the scientific concepts presented therein. Bernstein's theory of pedagogic discourse (1990, 2000) provided the sociological foundation to assess the exhibit-student interaction and allowed analysis of the influence of the characteristics of students, exhibits, and interactions on students' learning. Eight students (ages 12ndash;13 years of age) with distinct sociological characteristics participated in the study. Several findings emerged from the results. First, the characteristics of the students, exhibits, and interactions appeared to influence student learning. Second, to most students, what they did interactively (procedures) seems not to have had any direct consequence on what they learned (concept understanding). Third, the data analysis suggest an important role for designers and teachers in overcoming the limitations of exhibit-student interaction.

  6. Influence of atmospheric stability on wind-turbine wakes: A large-eddy simulation study

    Science.gov (United States)

    Abkar, Mahdi; Porté-Agel, Fernando

    2014-05-01

    In this study, large-eddy simulation is combined with a turbine model to investigate the influence of atmospheric stability on wind-turbine wakes. In the simulations, subgrid-scale turbulent fluxes are parameterized using tuning-free Lagrangian scale-dependent dynamic models. These models optimize the local value of the model coefficients based on the dynamics of the resolved scales. The turbine-induced forces are parameterized with an actuator-disk model with rotation. In this technique, blade-element theory is used to calculate the lift and drag forces acting on the blades. Emphasis is placed on the structure and characteristics of wind-turbine wakes in the cases where the incident flows to the turbine have the same mean velocity at the hub height but different stability conditions. The simulation results show that atmospheric stability has a significant effect on the spatial distribution of the mean velocity deficit and turbulent fluxes in the wake region. In particular, the magnitude of the velocity deficit increases with increasing stability in the atmosphere. In addition, the locations of the maximum turbulence intensity and turbulent stresses are closer to the turbine in convective boundary layer compared with neutral and stable ones. Detailed analysis of the resolved turbulent kinetic energy (TKE) budget inside the wake reveals also that the thermal stratification of the incoming wind considerably affects the magnitude and spatial distribution of the turbulent production, transport term and dissipation rate (transfer of energy to the subgrid scales). It is also shown that the near-wake region can be extended to a farther distance downstream in stable condition compared with neutral and unstable counterparts. In order to isolate the effect of atmospheric stability, additional simulations of neutrally-stratified atmospheric boundary layers are performed with the same turbulence intensity at hub height as convective and stable ones. The results show that the

  7. Chaotic and stable perturbed maps: 2-cycles and spatial models

    Science.gov (United States)

    Braverman, E.; Haroutunian, J.

    2010-06-01

    As the growth rate parameter increases in the Ricker, logistic and some other maps, the models exhibit an irreversible period doubling route to chaos. If a constant positive perturbation is introduced, then the Ricker model (but not the classical logistic map) experiences period doubling reversals; the break of chaos finally gives birth to a stable two-cycle. We outline the maps which demonstrate a similar behavior and also study relevant discrete spatial models where the value in each cell at the next step is defined only by the values at the cell and its nearest neighbors. The stable 2-cycle in a scalar map does not necessarily imply 2-cyclic-type behavior in each cell for the spatial generalization of the map.

  8. Spatial heterogeneity study of vegetation coverage at Heihe River Basin

    Science.gov (United States)

    Wu, Lijuan; Zhong, Bo; Guo, Liyu; Zhao, Xiangwei

    2014-11-01

    Spatial heterogeneity of the animal-landscape system has three major components: heterogeneity of resource distributions in the physical environment, heterogeneity of plant tissue chemistry, heterogeneity of movement modes by the animal. Furthermore, all three different types of heterogeneity interact each other and can either reinforce or offset one another, thereby affecting system stability and dynamics. In previous studies, the study areas are investigated by field sampling, which costs a large amount of manpower. In addition, uncertain in sampling affects the quality of field data, which leads to unsatisfactory results during the entire study. In this study, remote sensing data is used to guide the sampling for research on heterogeneity of vegetation coverage to avoid errors caused by randomness of field sampling. Semi-variance and fractal dimension analysis are used to analyze the spatial heterogeneity of vegetation coverage at Heihe River Basin. The spherical model with nugget is used to fit the semivariogram of vegetation coverage. Based on the experiment above, it is found, (1)there is a strong correlation between vegetation coverage and distance of vegetation populations within the range of 0-28051.3188m at Heihe River Basin, but the correlation loses suddenly when the distance greater than 28051.3188m. (2)The degree of spatial heterogeneity of vegetation coverage at Heihe River Basin is medium. (3)Spatial distribution variability of vegetation occurs mainly on small scales. (4)The degree of spatial autocorrelation is 72.29% between 25% and 75%, which means that spatial correlation of vegetation coverage at Heihe River Basin is medium high.

  9. Anthropogenic heat flux: advisable spatial resolutions when input data are scarce

    Science.gov (United States)

    Gabey, A. M.; Grimmond, C. S. B.; Capel-Timms, I.

    2018-02-01

    Anthropogenic heat flux (QF) may be significant in cities, especially under low solar irradiance and at night. It is of interest to many practitioners including meteorologists, city planners and climatologists. QF estimates at fine temporal and spatial resolution can be derived from models that use varying amounts of empirical data. This study compares simple and detailed models in a European megacity (London) at 500 m spatial resolution. The simple model (LQF) uses spatially resolved population data and national energy statistics. The detailed model (GQF) additionally uses local energy, road network and workday population data. The Fractions Skill Score (FSS) and bias are used to rate the skill with which the simple model reproduces the spatial patterns and magnitudes of QF, and its sub-components, from the detailed model. LQF skill was consistently good across 90% of the city, away from the centre and major roads. The remaining 10% contained elevated emissions and "hot spots" representing 30-40% of the total city-wide energy. This structure was lost because it requires workday population, spatially resolved building energy consumption and/or road network data. Daily total building and traffic energy consumption estimates from national data were within ± 40% of local values. Progressively coarser spatial resolutions to 5 km improved skill for total QF, but important features (hot spots, transport network) were lost at all resolutions when residential population controlled spatial variations. The results demonstrate that simple QF models should be applied with conservative spatial resolution in cities that, like London, exhibit time-varying energy use patterns.

  10. Temporal and spatial variability of wind resources in the United States as derived from the Climate Forecast System Reanalysis

    Science.gov (United States)

    Lejiang Yu; Shiyuan Zhong; Xindi Bian; Warren E. Heilman

    2015-01-01

    This study examines the spatial and temporal variability of wind speed at 80m above ground (the average hub height of most modern wind turbines) in the contiguous United States using Climate Forecast System Reanalysis (CFSR) data from 1979 to 2011. The mean 80-m wind exhibits strong seasonality and large spatial variability, with higher (lower) wind speeds in the...

  11. Bioactive hydroxyapatite/graphene composite coating and its corrosion stability in simulated body fluid

    Energy Technology Data Exchange (ETDEWEB)

    Janković, Ana; Eraković, Sanja [Faculty of Technology and Metallurgy, University of Belgrade, Karnegijeva 4, 11 000 Belgrade (Serbia); Mitrić, Miodrag [Vinča Institute of Nuclear Sciences, University of Belgrade, Mike Petrovića Alasa 12-14, 11 000 Belgrade (Serbia); Matić, Ivana Z.; Juranić, Zorica D. [Institute of Oncology and Radiology of Serbia, Pasterova 14, 11 000 Belgrade (Serbia); Tsui, Gary C.P.; Tang, Chak-yin [Department of Industrial and Systems Engineering, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong (China); Mišković-Stanković, Vesna [Faculty of Technology and Metallurgy, University of Belgrade, Karnegijeva 4, 11 000 Belgrade (Serbia); Rhee, Kyong Yop, E-mail: rheeky@khu.ac.kr [Department of Mechanical Engineering, Kyung Hee University, Yongin 449-701 (Korea, Republic of); Park, Soo Jin [Chemistry, College of Natural Sciences, Inha University, Incheon 402-751 (Korea, Republic of)

    2015-03-05

    Highlights: • Bioactive HAP/Gr coating on Ti was successfully obtained by EPD. • Increased fracture toughness of the HAP/Gr coating compared to pure HAP coating. • HAP/Gr coating exhibited superior biomimetic mineralization vs. pure HAP coating. • Gr improved the mechanical properties and thermal stability of HAP/Gr coating. • HAP/Gr coating was classified as non-cytotoxic against the targeted PBMC. - Abstract: The hydroxyapatite/graphene (HAP/Gr) composite was electrodeposited on Ti using the electrophoretic deposition process to obtain uniform bioactive coating with improved mechanical strength and favorable corrosion stability in simulated body fluid (SBF). Incorporation of Gr was verified by Raman spectroscopy, X-ray diffraction, Fourier transform infrared spectroscopy, thermogravimetric analysis, and X-ray photoelectron analysis. The HAP/Gr composite coating exhibited reduced surface cracks, nearly double the hardness, and elastic modulus increased by almost 50% compared to pure HAP coating, as estimated by a nanoindentation test. The bioactive HAP/Gr composite coating provided a newly formed apatite layer in SBF with enhanced corrosion stability, as evidenced by electrochemical impedance spectroscopy. The thermal stability of the HAP/Gr coating was improved in comparison to the pure HAP coating, and the Ca/P ratio was closer to the stoichiometric value. No antibacterial activity against Staphylococcus aureus or Escherichia coli could be verified. The HAP/Gr composite coating was classified as non-cytotoxic when tested against healthy peripheral blood mononuclear cells (PBMC)

  12. Bioactive hydroxyapatite/graphene composite coating and its corrosion stability in simulated body fluid

    International Nuclear Information System (INIS)

    Janković, Ana; Eraković, Sanja; Mitrić, Miodrag; Matić, Ivana Z.; Juranić, Zorica D.; Tsui, Gary C.P.; Tang, Chak-yin; Mišković-Stanković, Vesna; Rhee, Kyong Yop; Park, Soo Jin

    2015-01-01

    Highlights: • Bioactive HAP/Gr coating on Ti was successfully obtained by EPD. • Increased fracture toughness of the HAP/Gr coating compared to pure HAP coating. • HAP/Gr coating exhibited superior biomimetic mineralization vs. pure HAP coating. • Gr improved the mechanical properties and thermal stability of HAP/Gr coating. • HAP/Gr coating was classified as non-cytotoxic against the targeted PBMC. - Abstract: The hydroxyapatite/graphene (HAP/Gr) composite was electrodeposited on Ti using the electrophoretic deposition process to obtain uniform bioactive coating with improved mechanical strength and favorable corrosion stability in simulated body fluid (SBF). Incorporation of Gr was verified by Raman spectroscopy, X-ray diffraction, Fourier transform infrared spectroscopy, thermogravimetric analysis, and X-ray photoelectron analysis. The HAP/Gr composite coating exhibited reduced surface cracks, nearly double the hardness, and elastic modulus increased by almost 50% compared to pure HAP coating, as estimated by a nanoindentation test. The bioactive HAP/Gr composite coating provided a newly formed apatite layer in SBF with enhanced corrosion stability, as evidenced by electrochemical impedance spectroscopy. The thermal stability of the HAP/Gr coating was improved in comparison to the pure HAP coating, and the Ca/P ratio was closer to the stoichiometric value. No antibacterial activity against Staphylococcus aureus or Escherichia coli could be verified. The HAP/Gr composite coating was classified as non-cytotoxic when tested against healthy peripheral blood mononuclear cells (PBMC)

  13. Spatial Linkage and Urban Expansion: AN Urban Agglomeration View

    Science.gov (United States)

    Jiao, L. M.; Tang, X.; Liu, X. P.

    2017-09-01

    Urban expansion displays different characteristics in each period. From the perspective of the urban agglomeration, studying the spatial and temporal characteristics of urban expansion plays an important role in understanding the complex relationship between urban expansion and network structure of urban agglomeration. We analyze urban expansion in the Yangtze River Delta Urban Agglomeration (YRD) through accessibility to and spatial interaction intensity from core cities as well as accessibility of road network. Results show that: (1) Correlation between urban expansion intensity and spatial indicators such as location and space syntax variables is remarkable and positive, while it decreases after rapid expansion. (2) Urban expansion velocity displays a positive correlation with spatial indicators mentioned above in the first (1980-1990) and second (1990-2000) period. However, it exhibits a negative relationship in the third period (2000-2010), i.e., cities located in the periphery of urban agglomeration developing more quickly. Consequently, the hypothesis of convergence of urban expansion in rapid expansion stage is put forward. (3) Results of Zipf's law and Gibrat's law show urban expansion in YRD displays a convergent trend in rapid expansion stage, small and medium-sized cities growing faster. This study shows that spatial linkage plays an important but evolving role in urban expansion within the urban agglomeration. In addition, it serves as a reference to the planning of Yangtze River Delta Urban Agglomeration and regulation of urban expansion of other urban agglomerations.

  14. Eudragit L/HPMCAS blend enteric-coated lansoprazole pellets: enhanced drug stability and oral bioavailability.

    Science.gov (United States)

    Fang, Yu; Wang, Guozheng; Zhang, Rong; Liu, Zhihua; Liu, Zhenghua; Wu, Xiaohui; Cao, Deying

    2014-06-01

    The objectives of the present work were to use blends of Eudragit L and hydroxypropyl methylcellulose acetate succinate (HPMCAS) as enteric film coatings for lansoprazole (LSP) pellets. The enteric-coated pellets were prepared with a fluid-bed coater. The influence of the blend ratio, type of plasticizer, plasticizer level, coating level, and curing conditions on gastric stability in vitro drug release and drug stability was evaluated. Furthermore, the bioavailability of the blend-coated pellets in beagle dogs was also performed. The blend-coated pellets exhibited significant improvement of gastric stability and drug stability compared to the pure polymer-coated pellets. Moreover, the AUC values of blend-coated pellets were greater than that of the pure polymer-coated pellets. It was concluded that the using blends of Eudragit L and HPMCAS as enteric film coatings for LSP pellets improved the drug stability and oral bioavailability.

  15. Optimal Strong-Stability-Preserving Runge–Kutta Time Discretizations for Discontinuous Galerkin Methods

    KAUST Repository

    Kubatko, Ethan J.; Yeager, Benjamin A.; Ketcheson, David I.

    2013-01-01

    Discontinuous Galerkin (DG) spatial discretizations are often used in a method-of-lines approach with explicit strong-stability-preserving (SSP) Runge–Kutta (RK) time steppers for the numerical solution of hyperbolic conservation laws. The time steps that are employed in this type of approach must satisfy Courant–Friedrichs–Lewy stability constraints that are dependent on both the region of absolute stability and the SSP coefficient of the RK method. While existing SSPRK methods have been optimized with respect to the latter, it is in fact the former that gives rise to stricter constraints on the time step in the case of RKDG stability. Therefore, in this work, we present the development of new “DG-optimized” SSPRK methods with stability regions that have been specifically designed to maximize the stable time step size for RKDG methods of a given order in one space dimension. These new methods represent the best available RKDG methods in terms of computational efficiency, with significant improvements over methods using existing SSPRK time steppers that have been optimized with respect to SSP coefficients. Second-, third-, and fourth-order methods with up to eight stages are presented, and their stability properties are verified through application to numerical test cases.

  16. Optimal Strong-Stability-Preserving Runge–Kutta Time Discretizations for Discontinuous Galerkin Methods

    KAUST Repository

    Kubatko, Ethan J.

    2013-10-29

    Discontinuous Galerkin (DG) spatial discretizations are often used in a method-of-lines approach with explicit strong-stability-preserving (SSP) Runge–Kutta (RK) time steppers for the numerical solution of hyperbolic conservation laws. The time steps that are employed in this type of approach must satisfy Courant–Friedrichs–Lewy stability constraints that are dependent on both the region of absolute stability and the SSP coefficient of the RK method. While existing SSPRK methods have been optimized with respect to the latter, it is in fact the former that gives rise to stricter constraints on the time step in the case of RKDG stability. Therefore, in this work, we present the development of new “DG-optimized” SSPRK methods with stability regions that have been specifically designed to maximize the stable time step size for RKDG methods of a given order in one space dimension. These new methods represent the best available RKDG methods in terms of computational efficiency, with significant improvements over methods using existing SSPRK time steppers that have been optimized with respect to SSP coefficients. Second-, third-, and fourth-order methods with up to eight stages are presented, and their stability properties are verified through application to numerical test cases.

  17. Chaotic convective behavior and stability analysis of a fractional viscoelastic fluids model in porous media

    KAUST Repository

    N'Doye, Ibrahima; Laleg-Kirati, Taous-Meriem

    2015-01-01

    , and show the existence of chaos. The behavior and stability analysis of the integer-order and the fractional commensurate and non-commensurate orders of a fractional viscoelastic fluids system, which exhibits chaos, are presented as well.

  18. Throughfall and its spatial variability beneath xerophytic shrub canopies within water-limited arid desert ecosystems

    Science.gov (United States)

    Zhang, Ya-feng; Wang, Xin-ping; Hu, Rui; Pan, Yan-xia

    2016-08-01

    Throughfall is known to be a critical component of the hydrological and biogeochemical cycles of forested ecosystems with inherently temporal and spatial variability. Yet little is understood concerning the throughfall variability of shrubs and the associated controlling factors in arid desert ecosystems. Here we systematically investigated the variability of throughfall of two morphological distinct xerophytic shrubs (Caragana korshinskii and Artemisia ordosica) within a re-vegetated arid desert ecosystem, and evaluated the effects of shrub structure and rainfall characteristics on throughfall based on heavily gauged throughfall measurements at the event scale. We found that morphological differences were not sufficient to generate significant difference (P < 0.05) in throughfall between two studied shrub species under the same rainfall and meteorological conditions in our study area, with a throughfall percentage of 69.7% for C. korshinskii and 64.3% for A. ordosica. We also observed a highly variable patchy pattern of throughfall beneath individual shrub canopies, but the spatial patterns appeared to be stable among rainfall events based on time stability analysis. Throughfall linearly increased with the increasing distance from the shrub base for both shrubs, and radial direction beneath shrub canopies had a pronounced impact on throughfall. Throughfall variability, expressed as the coefficient of variation (CV) of throughfall, tended to decline with the increase in rainfall amount, intensity and duration, and stabilized passing a certain threshold. Our findings highlight the great variability of throughfall beneath the canopies of xerophytic shrubs and the time stability of throughfall pattern among rainfall events. The spatially heterogeneous and temporally stable throughfall is expected to generate a dynamic patchy distribution of soil moisture beneath shrub canopies within arid desert ecosystems.

  19. Stabilization of structure in near-infrared fluorescent proteins by binding of biliverdin chromophore

    Science.gov (United States)

    Stepanenko, Olesya V.; Stepanenko, Olga V.; Bublikov, G. S.; Kuznetsova, I. M.; Verkhusha, V. V.; Turoverov, K. K.

    2017-07-01

    Near-infrared fluorescent proteins (NIR FPs) engineered from bacterial phytochromes and their mutants with different location of Cys residues, which able to bind a biliverdin chromophore, or without these Cys residues were studied using intrinsic tryptophan fluorescence, NIR fluorescence and circular dichroism. It was shown that a covalent binding of the biliverdin chromophore to a Cys residue via thioether group substantially stabilizes the spatial structure of NIR FPs. The stability of the protein structure and the chromophore association strength strongly depends on the location of Cys residues and decreases in the following order: a protein with Cys residues in both domains, a protein with Cys in PAS domains, and a protein with Cys in GAF domains. NIR FPs without Cys residues capable to covalently attach biliverdin have the lowest stability, comparable to NIR FP apoforms.

  20. The stability and slow dynamics of spot patterns in the 2D Brusselator model: The effect of open systems and heterogeneities

    Science.gov (United States)

    Tzou, J. C.; Ward, M. J.

    2018-06-01

    Spot patterns, whereby the activator field becomes spatially localized near certain dynamically-evolving discrete spatial locations in a bounded multi-dimensional domain, is a common occurrence for two-component reaction-diffusion (RD) systems in the singular limit of a large diffusivity ratio. In previous studies of 2-D localized spot patterns for various specific well-known RD systems, the domain boundary was assumed to be impermeable to both the activator and inhibitor, and the reaction-kinetics were assumed to be spatially uniform. As an extension of this previous theory, we use formal asymptotic methods to study the existence, stability, and slow dynamics of localized spot patterns for the singularly perturbed 2-D Brusselator RD model when the domain boundary is only partially impermeable, as modeled by an inhomogeneous Robin boundary condition, or when there is an influx of inhibitor across the domain boundary. In our analysis, we will also allow for the effect of a spatially variable bulk feed term in the reaction kinetics. By applying our extended theory to the special case of one-spot patterns and ring patterns of spots inside the unit disk, we provide a detailed analysis of the effect on spot patterns of these three different sources of heterogeneity. In particular, when there is an influx of inhibitor across the boundary of the unit disk, a ring pattern of spots can become pinned to a ring-radius closer to the domain boundary. Under a Robin condition, a quasi-equilibrium ring pattern of spots is shown to exhibit a novel saddle-node bifurcation behavior in terms of either the inhibitor diffusivity, the Robin constant, or the ambient background concentration. A spatially variable bulk feed term, with a concentrated source of "fuel" inside the domain, is shown to yield a saddle-node bifurcation structure of spot equilibria, which leads to qualitatively new spot-pinning behavior. Results from our asymptotic theory are validated from full numerical

  1. Impaired spatial and contextual memory formation in galectin-1 deficient mice

    Directory of Open Access Journals (Sweden)

    Sakaguchi Masanori

    2011-09-01

    Full Text Available Abstract Galectins are a 15 member family of carbohydrate-binding proteins that have been implicated in cancer, immunity, inflammation and development. While galectins are expressed in the central nervous system, little is known about their function in the adult brain. Previously we have shown that galectin-1 (gal-1 is expressed in the adult hippocampus, and, in particular, in putative neural stem cells in the subgranular zone. To evaluate how gal-1 might contribute to hippocampal memory function here we studied galectin-1 null mutant (gal-1-/- mice. Compared to their wildtype littermate controls, gal-1-/- mice exhibited impaired spatial learning in the water maze and contextual fear learning. Interestingly, tone fear conditioning was normal in gal-1-/- mice suggesting that loss of gal-1 might especially impact hippocampal learning and memory. Furthermore, gal-1-/- mice exhibited normal motor function, emotion and sensory processing in a battery of other behavioral tests, suggesting that non-mnemonic performance deficits are unlikely to account for the spatial and contextual learning deficits. Together, these data reveal a role for galectin-carbohydrate signalling in hippocampal memory function.

  2. Energy Stability Analysis of Some Fully Discrete Numerical Schemes for Incompressible Navier–Stokes Equations on Staggered Grids

    KAUST Repository

    Chen, Huangxin; Sun, Shuyu; Zhang, Tao

    2017-01-01

    In this paper we consider the energy stability estimates for some fully discrete schemes which both consider time and spatial discretizations for the incompressible Navier–Stokes equations. We focus on three kinds of fully discrete schemes, i

  3. Non-standard spatial statistics and spatial econometrics

    CERN Document Server

    Griffith, Daniel A

    2011-01-01

    Spatial statistics and spatial econometrics are recent sprouts of the tree "spatial analysis with measurement". Still, several general themes have emerged. Exploring selected fields of possible interest is tantalizing, and this is what the authors aim here.

  4. Investigating local controls on temporal stability of soil water content using sensor network data and an inverse modeling approach

    Science.gov (United States)

    Qu, W.; Bogena, H. R.; Huisman, J. A.; Martinez, G.; Pachepsky, Y. A.; Vereecken, H.

    2013-12-01

    Soil water content is a key variable in the soil, vegetation and atmosphere continuum with high spatial and temporal variability. Temporal stability of soil water content (SWC) has been observed in multiple monitoring studies and the quantification of controls on soil moisture variability and temporal stability presents substantial interest. The objective of this work was to assess the effect of soil hydraulic parameters on the temporal stability. The inverse modeling based on large observed time series SWC with in-situ sensor network was used to estimate the van Genuchten-Mualem (VGM) soil hydraulic parameters in a small grassland catchment located in western Germany. For the inverse modeling, the shuffled complex evaluation (SCE) optimization algorithm was coupled with the HYDRUS 1D code. We considered two cases: without and with prior information about the correlation between VGM parameters. The temporal stability of observed SWC was well pronounced at all observation depths. Both the spatial variability of SWC and the robustness of temporal stability increased with depth. Calibrated models both with and without prior information provided reasonable correspondence between simulated and measured time series of SWC. Furthermore, we found a linear relationship between the mean relative difference (MRD) of SWC and the saturated SWC (θs). Also, the logarithm of saturated hydraulic conductivity (Ks), the VGM parameter n and logarithm of α were strongly correlated with the MRD of saturation degree for the prior information case, but no correlation was found for the non-prior information case except at the 50cm depth. Based on these results we propose that establishing relationships between temporal stability and spatial variability of soil properties presents a promising research avenue for a better understanding of the controls on soil moisture variability. Correlation between Mean Relative Difference of soil water content (or saturation degree) and inversely

  5. Exhibition - Mathematics, A Beautiful Elsewhere

    CERN Multimedia

    2011-01-01

    From 21 October 2011 to 18 March 2012, the Fondation Cartier pour l’art contemporain will present the exhibition Mathematics: A Beautiful Elsewhere, an exhibition developed in association with the Institut des Hautes Études Scientifiques (IHÉS) and under the patronage of UNESCO. For this unprecedented event, the foundation invited mathematicians to work with artists with whom it has previously worked to create an exhibition that allows visitors to see, hear, do, interpret and think about mathematics. By bringing mathematics into its premises, the Fondation Cartier is itself undergoing the “sudden change of scenery” described by mathematician Alexandre Grothendieck. More information is available here. Fondation Cartier pour l’art contemporain 261, boulevard Raspail 75014 Paris http://fondation.cartier.com Private Visit For professors, researchers and all the staff of Mathematics departments...

  6. How noise and coupling influence leading indicators of population extinction in a spatially extended ecological system.

    Science.gov (United States)

    O'Regan, Suzanne M

    2018-12-01

    Anticipating critical transitions in spatially extended systems is a key topic of interest to ecologists. Gradually declining metapopulations are an important example of a spatially extended biological system that may exhibit a critical transition. Theory for spatially extended systems approaching extinction that accounts for environmental stochasticity and coupling is currently lacking. Here, we develop spatially implicit two-patch models with additive and multiplicative forms of environmental stochasticity that are slowly forced through population collapse, through changing environmental conditions. We derive patch-specific expressions for candidate indicators of extinction and test their performance via a simulation study. Coupling and spatial heterogeneities decrease the magnitude of the proposed indicators in coupled populations relative to isolated populations, and the noise regime and the degree of coupling together determine trends in summary statistics. This theory may be readily applied to other spatially extended ecological systems, such as coupled infectious disease systems on the verge of elimination.

  7. Feedback-stabilized fractional fringe laser interferometer for plasma density measurements

    International Nuclear Information System (INIS)

    Schneider, J.; Robertson, S.

    1979-01-01

    A feedback stabilization technique is described for a fractional fringe interferometer measuring plasma electron densities. Using this technique, a CO 2 laser Michelson interferometer with a pyroelectric detector exhibited a sensitivity of 3.4 x 10 -4 fringe on a 1-ms time scale and, due to acoustic pickup, 1.8 x 10 -2 fringe on a 10-ms time scale. The rise time is 45 μs. Stabilization against slow drifts in mirror distances is achieved by an electromechanically translated mirror driven by a servo system having a 0.2-s response time. A mechanical chopper in one of the two beam paths generates the signal which drives the servo system

  8. Preparation of poly(N-vinylpyrrolidone-stabilized ZnO colloid nanoparticles

    Directory of Open Access Journals (Sweden)

    Tatyana Gutul

    2014-04-01

    Full Text Available We propose a method for the synthesis of a colloidal ZnO solution with poly(N-vinylpyrrolidone (PVP as stabilizer. Stable colloidal solutions with good luminescence properties are obtained by using PVP as stabilizer in the synthesis of ZnO nanoparticles by a sol–gel method assisted by ultrasound. Nanoparticles with sizes of 30–40 nm in a PVP matrix are produced as a solid product. The colloidal ZnO/PVP/methanol solution, apart from the most intense PL band at 356 nm coming from the PVP, exhibits a strong PL band at 376 nm (3.30 eV which corresponds to the emission of the free exciton recombination in ZnO nanoparticles.

  9. Developing a Geoinformatic-engineering Stability Modeling Method, using Field Data and GIS Environment: A Case Study from Al Qarara Area in Wadi Musa, Jordan

    Directory of Open Access Journals (Sweden)

    Mohammmad Al Farajat

    2015-03-01

    Full Text Available DOI:10.17014/ijog.2.1.1-21By applying detailed geological field surveys, the spatial factors affecting geo-engineering stability were used to develop a geo-engineering stability modeling method to identify areas under potential threat of landsliding. The factors affecting geo-engineering stability in Al Qarara area in Petra-Jordan were studied and given assumed rates of importance, where optimization process was run by lag iterations; the produced spatial layers of the different factors were gathered and modeled using GIS; a final stability map was produced using an optimized equation. The produced map was validated qualitatively and quantitatively, where a comparison was made between the reality in the field and several maps of different equation. The modeling method which was developed in the context of this study proved to be suitable to produce micro-zonation maps of areas having landslide risk. Further applications on the method in other areas suffering landslides will further improve it.

  10. Local dynamic stability of lower extremity joints in lower limb amputees during slope walking.

    Science.gov (United States)

    Chen, Jin-Ling; Gu, Dong-Yun

    2013-01-01

    Lower limb amputees have a higher fall risk during slope walking compared with non-amputees. However, studies on amputees' slope walking were not well addressed. The aim of this study was to identify the difference of slope walking between amputees and non-amputees. Lyapunov exponents λS was used to estimate the local dynamic stability of 7 transtibial amputees' and 7 controls' lower extremity joint kinematics during uphill and downhill walking. Compared with the controls, amputees exhibited significantly lower λS in hip (P=0.04) and ankle (P=0.01) joints of the sound limb, and hip joints (P=0.01) of the prosthetic limb during uphill walking, while they exhibited significantly lower λS in knee (P=0.02) and ankle (P=0.03) joints of the sound limb, and hip joints (P=0.03) of the prosthetic limb during downhill walking. Compared with amputees level walking, they exhibited significantly lower λS in ankle joints of the sound limb during both uphill (P=0.01) and downhill walking (P=0.01). We hypothesized that the better local dynamic stability of amputees was caused by compensation strategy during slope walking.

  11. A versatile synthesis of highly bactericidal Myramistin® stabilized silver nanoparticles

    Science.gov (United States)

    Vertelov, G. K.; Krutyakov, Yu A.; Efremenkova, O. V.; Olenin, A. Yu; Lisichkin, G. V.

    2008-09-01

    Silver nanoparticles stabilized by a well-known antibacterial surfactant benzyldimethyl[3-(myristoylamino)propyl]ammonium chloride (Myramistin®) were produced for the first time by borohydride reduction of silver chloride sol in water. Stable aqueous dispersions of silver nanoparticles without evident precipitation for several months could be obtained. In vitro bactericidal tests showed that Myramistin® capped silver NPs exhibited notable activity against six different microorganisms—gram-positive and gram-negative bacteria, yeasts and fungi. The activity was up to 20 times higher (against E. coli) compared to Myramistin® at the same concentrations and on average 2 times higher if compared with citrate-stabilized NPs.

  12. Time-varying correlations in global real estate markets: A multivariate GARCH with spatial effects approach

    Science.gov (United States)

    Gu, Huaying; Liu, Zhixue; Weng, Yingliang

    2017-04-01

    The present study applies the multivariate generalized autoregressive conditional heteroscedasticity (MGARCH) with spatial effects approach for the analysis of the time-varying conditional correlations and contagion effects among global real estate markets. A distinguishing feature of the proposed model is that it can simultaneously capture the spatial interactions and the dynamic conditional correlations compared with the traditional MGARCH models. Results reveal that the estimated dynamic conditional correlations have exhibited significant increases during the global financial crisis from 2007 to 2009, thereby suggesting contagion effects among global real estate markets. The analysis further indicates that the returns of the regional real estate markets that are in close geographic and economic proximities exhibit strong co-movement. In addition, evidence of significantly positive leverage effects in global real estate markets is also determined. The findings have significant implications on global portfolio diversification opportunities and risk management practices.

  13. Human Exhibitions

    DEFF Research Database (Denmark)

    Andreassen, Rikke

    light on the staging of exhibitions, the daily life of the exhibitees, the wider connections between shows across Europe and the thinking of the time on matters of race, science, gender and sexuality. A window onto contemporary racial understandings, the book presents interviews with the descendants...... of displayed people, connecting the attitudes and science of the past with both our (continued) modern fascination with ‘the exotic’, and contemporary language and popular culture. As such, it will be of interest to scholars of sociology, anthropology and history working in the areas of gender and sexuality...

  14. Anniversary Exhibition. Nechvolodov.

    Directory of Open Access Journals (Sweden)

    - -

    2006-03-01

    Full Text Available On the 10th of August, 2005 in Tartu (the second biggest educational and cultural city in Estonia Stanislav Nechvolodov's exhibition was opened to show the 5-year cycle of his work, traditional for the author and his admirers. At the opening ceremony Nechvolodov said that the exhibition was the last one and appointed on his 70th anniversary.The architectural and building society in Irkutsk remembers Stanislav Nechvolodov as an architect working on dwelling and civil buildings in 1960-70s. Below are some extracts from the Estonian press.«Postimees» newspaper, December 1993. The interview «Expressionistic naturalist, conservative Nechvolodov» by journalist Eric Linnumyagi. He asks about all the details and describes the troubles experienced by Nechvolodov during the perestroika period in Estonia, for example: the Tartu University refused to install the sculpture of Socrat, the art school refused to engage him as an instructor, the sculpture of Socrat moved to Vrotzlav, Poland, and Nechvolodov moved to Poland to read lectures there.«Tartu» newspaper, November 2000. Mats Oun, artist, says in the article «Nechvolodov: a man of Renaissance»: «Nechvolodov works in Estonia, his works are placed in many local and foreign museums. Regardless some insignificant faults, he deserves a high estimation, and his manysided open exhibition can be an example for other artists. He is a man of Renaissance».

  15. Creating Virtual Exhibitions for Educational and Cultural Development

    Directory of Open Access Journals (Sweden)

    Gabriela DUMITRESCU

    2014-01-01

    Full Text Available The paper presents different tools and mechanisms to implement a virtual exhibition in different cultural areas, such as museums and libraries. Quality characteristics of virtual exhibitions are identified and described. The possibility to create native mobile applications for virtual exhibitions presentation is analyzed. The functional flow of creating a virtual exhibition is presented and discussed. The Seals - History Treasure exhibition is presented and significant historical documents are revealed.

  16. Enhanced Cycling Stability of Rechargeable Li-O2 Batteries Using High Concentration Electrolytes

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Bin; Xu, Wu; Yan, Pengfei; Sun, Xiuliang; Bowden, Mark E.; Read, Jeffrey; Qian, Jiangfeng; Mei, Donghai; Wang, Chong M.; Zhang, Jiguang

    2016-01-26

    The electrolyte stability against reactive reduced-oxygen species is crucial for the development of rechargeable Li-O2 batteries. In this work, we systematically investigated the effect of lithium salt concentration in 1,2-dimethoxyethane (DME)-based electrolytes on the cycling stability of Li-O2 batteries. Cells with high concentration electrolyte illustrate largely enhanced cycling stability under both the full discharge/charge (2.0-4.5 V vs. Li/Li+) and the capacity limited (at 1,000 mAh g-1) conditions. These cells also exhibit much less reaction-residual on the charged air electrode surface, and much less corrosion to the Li metal anode. The density functional theory calculations are conducted on the molecular orbital energies of the electrolyte components and the Gibbs activation barriers for superoxide radical anion to attack DME solvent and Li+-(DME)n solvates. In a highly concentrated electrolyte, all DME molecules have been coordinated with salt and the C-H bond scission of a DME molecule becomes more difficult. Therefore, the decomposition of highly concentrated electrolyte in a Li-O2 battery can be mitigated and both air-cathodes and Li-metal anodes exhibits much better reversibility. As a results, the cyclability of Li-O2 can be largely improved.

  17. Adaptability and phenotypic stability of soybean cultivars for grain yield and oil content.

    Science.gov (United States)

    Silva, K B; Bruzi, A T; Zuffo, A M; Zambiazzi, E V; Soares, I O; de Rezende, P M; Fronza, V; Vilela, G D L; Botelho, F B S; Teixeira, C M; de O Coelho, M A

    2016-04-25

    The aim of this study was to verify the adaptability and stability of soybean cultivars with regards to yield and oil content. Data of soybean yield and oil content were used from experiments set up in six environments in the 2011/12 and 2012/13 crop seasons in the municipalities of Patos de Minas, Uberaba, Lavras, and São Gotardo, Minas Gerais, Brazil, testing 36 commercial soybean cultivars of both conventional and transgenic varieties. The Wricke method and GGE biplot analysis were used to evaluate adaptability and stability of these cultivars. Large variations were observed in grain yield in relation to the different environments studied, showing that these materials are adaptable. The cultivars exhibited significant differences in oil content. The cultivars BRSGO204 (Goiânia) and BRSMG (Garantia) exhibited the greatest average grain yield in the different environments studied, and the cultivar BRSMG 760 SRR had the greatest oil content among the cultivars evaluated. Ecovalence was adopted to identify the most stable cultivars, and the estimates were nearly uniform both for grain yield and oil content, showing a variation of 0.07 and 0.01%, respectively. The GGE biplot was efficient at identifying cultivars with high adaptability and phenotype stability.

  18. Digital Image Stabilization Method Based on Variational Mode Decomposition and Relative Entropy

    Directory of Open Access Journals (Sweden)

    Duo Hao

    2017-11-01

    Full Text Available Cameras mounted on vehicles frequently suffer from image shake due to the vehicles’ motions. To remove jitter motions and preserve intentional motions, a hybrid digital image stabilization method is proposed that uses variational mode decomposition (VMD and relative entropy (RE. In this paper, the global motion vector (GMV is initially decomposed into several narrow-banded modes by VMD. REs, which exhibit the difference of probability distribution between two modes, are then calculated to identify the intentional and jitter motion modes. Finally, the summation of the jitter motion modes constitutes jitter motions, whereas the subtraction of the resulting sum from the GMV represents the intentional motions. The proposed stabilization method is compared with several known methods, namely, medium filter (MF, Kalman filter (KF, wavelet decomposition (MD method, empirical mode decomposition (EMD-based method, and enhanced EMD-based method, to evaluate stabilization performance. Experimental results show that the proposed method outperforms the other stabilization methods.

  19. Enhancement of temozolomide stability by loading in chitosan-carboxylated polylactide-based nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Di Martino, Antonio; Kucharczyk, Pavel; Capakova, Zdenka; Humpolicek, Petr; Sedlarik, Vladimir, E-mail: sedlarik@ft.utb.cz [Tomas Bata University in Zlín, Centre of Polymer Systems, University Institute (Czech Republic)

    2017-02-15

    In the presented work, amphiphilic nanoparticles based on chitosan and carboxy-enriched polylactic acid have been prepared to improve the stability of the pro-drug temozolomide in physiological media by encapsulation. The carrier, with a diameter in the range of 150–180 nm, was able to accommodate up to 800 μg of temozolomide per mg of polymer. The obtained formulation showed good stability in physiological condition and preparation media up to 1 month. Temozolomide loaded inside the carrier exhibited greater stability than the free drug, in particular in simulated physiological solution at pH 7.4 where the hydrolysis in the inactive metabolite was clearly delayed. CS-SPLA nanoparticles demonstrated a pH-dependent TMZ release kinetics with the opportunity to increase or decrease the rate. Mass spectroscopy, UV-Vis analysis, and in vitro cell tests confirmed the improvement in temozolomide stability and effectiveness when loaded into the polymeric carrier, in comparison with the free drug.

  20. Stability of impulsively-driven natural convection with unsteady base state: implications of an adiabatic boundary

    International Nuclear Information System (INIS)

    Ihle, Christian F.; Nino, Yarko

    2011-01-01

    Stability conditions of a quiescent, horizontally infinite fluid layer with adiabatic bottom subject to sudden cooling from above are studied. Here, at difference from Rayleigh-Benard convection, the temperature base state is never steady. Instability limits are studied using linear analysis while stability is analyzed using the energy method. Critical stability curves in terms of Rayleigh numbers and convection onset times were obtained for several kinematic boundary conditions. Stability curves resulting from energy and linear approaches exhibit the same temporal growth rate for large values of time, suggesting a bound for the temporal asymptotic behavior of the energy method. - Highlights: → Non-penetrative convection appears after a time-evolving temperature base state. → Global stability and instability limits were analyzed. → Critical Rayleigh numbers were computed for different kinematic boundary conditions. → Adiabatic, bottom boundary was found to have a de-stabilizing effect. → System is less stable than in Benard convection.

  1. Noise-induced stability in dryland plant ecosystems.

    Science.gov (United States)

    D'Odorico, Paolo; Laio, Francesco; Ridolfi, Luca

    2005-08-02

    Dryland plant ecosystems tend to exhibit bistable dynamics with two preferential configurations of bare and vegetated soils. Climate fluctuations are usually believed to act as a source of disturbance on these ecosystems and to reduce their stability and resilience. In contrast, this work shows that random interannual fluctuations of precipitation may lead to the emergence of an intermediate statistically stable condition between the two stable states of the deterministic dynamics of vegetation. As a result, there is an enhancement of ecosystem resilience and a decrease in the likelihood of catastrophic shifts to the desert state.

  2. Enhanced planar perovskite solar cell efficiency and stability using a perovskite/PCBM heterojunction formed in one step.

    Science.gov (United States)

    Zhou, Long; Chang, Jingjing; Liu, Ziye; Sun, Xu; Lin, Zhenhua; Chen, Dazheng; Zhang, Chunfu; Zhang, Jincheng; Hao, Yue

    2018-02-08

    Perovskite/PCBM heterojunctions are efficient for fabricating perovskite solar cells with high performance and long-term stability. In this study, an efficient perovskite/PCBM heterojunction was formed via conventional sequential deposition and one-step formation processes. Compared with conventional deposition, the one-step process was more facile, and produced a perovskite thin film of substantially improved quality due to fullerene passivation. Moreover, the resulting perovskite/PCBM heterojunction exhibited more efficient carrier transfer and extraction, and reduced carrier recombination. The perovskite solar cell device based on one-step perovskite/PCBM heterojunction formation exhibited a higher maximum PCE of 17.8% compared with that from the conventional method (13.7%). The device also showed exceptional stability, retaining 83% of initial PCE after 60 days of storage under ambient conditions.

  3. The exploration of the exhibition informatization

    Science.gov (United States)

    Zhang, Jiankang

    2017-06-01

    The construction and management of exhibition informatization is the main task and choke point during the process of Chinese exhibition industry’s transformation and promotion. There are three key points expected to realize a breakthrough during the construction of Chinese exhibition informatization, and the three aspects respectively are adopting service outsourcing to construct and maintain the database, adopting advanced chest card technology to collect various kinds of information, developing statistics analysis to maintain good cutomer relations. The success of Chinese exhibition informatization mainly calls for mature suppliers who can provide construction and maintenance of database, the proven technology, a sense of data security, advanced chest card technology, the ability of data mining and analysis and the ability to improve the exhibition service basing on the commercial information got from the data analysis. Several data security measures are expected to apply during the process of system developing, including the measures of the terminal data security, the internet data security, the media data security, the storage data security and the application data security. The informatization of this process is based on the chest card designing. At present, there are several types of chest card technology: bar code chest card; two-dimension code card; magnetic stripe chest card; smart-chip chest card. The information got from the exhibition data will help the organizers to make relevant service strategies, quantify the accumulated indexes of the customers, and improve the level of the customer’s satisfaction and loyalty, what’s more, the information can also provide more additional services like the commercial trips, VIP ceremonial reception.

  4. Spatial scales of pollution from variable resolution satellite imaging

    International Nuclear Information System (INIS)

    Chudnovsky, Alexandra A.; Kostinski, Alex; Lyapustin, Alexei; Koutrakis, Petros

    2013-01-01

    The Moderate Resolution Imaging Spectroradiometer (MODIS) provides daily global coverage, but the 10 km resolution of its aerosol optical depth (AOD) product is not adequate for studying spatial variability of aerosols in urban areas. Recently, a new Multi-Angle Implementation of Atmospheric Correction (MAIAC) algorithm was developed for MODIS which provides AOD at 1 km resolution. Using MAIAC data, the relationship between MAIAC AOD and PM 2.5 as measured by the EPA ground monitoring stations was investigated at varying spatial scales. Our analysis suggested that the correlation between PM 2.5 and AOD decreased significantly as AOD resolution was degraded. This is so despite the intrinsic mismatch between PM 2.5 ground level measurements and AOD vertically integrated measurements. Furthermore, the fine resolution results indicated spatial variability in particle concentration at a sub-10 km scale. Finally, this spatial variability of AOD within the urban domain was shown to depend on PM 2.5 levels and wind speed. - Highlights: ► The correlation between PM 2.5 and AOD decreases as AOD resolution is degraded. ► High resolution MAIAC AOD 1 km retrieval can be used to investigate within-city PM 2.5 variability. ► Low pollution days exhibit higher spatial variability of AOD and PM 2.5 then moderate pollution days. ► AOD spatial variability within urban area is higher during the lower wind speed conditions. - The correlation between PM 2.5 and AOD decreases as AOD resolution is degraded. The new high-resolution MAIAC AOD retrieval has the potential to capture PM 2.5 variability at the intra-urban scale.

  5. Spatial heterogeneity of climate change as an experiential basis for skepticism.

    Science.gov (United States)

    Kaufmann, Robert K; Mann, Michael L; Gopal, Sucharita; Liederman, Jackie A; Howe, Peter D; Pretis, Felix; Tang, Xiaojing; Gilmore, Michelle

    2017-01-03

    We postulate that skepticism about climate change is partially caused by the spatial heterogeneity of climate change, which exposes experiential learners to climate heuristics that differ from the global average. This hypothesis is tested by formalizing an index that measures local changes in climate using station data and comparing this index with survey-based model estimates of county-level opinion about whether global warming is happening. Results indicate that more stations exhibit cooling and warming than predicted by random chance and that spatial variations in these changes can account for spatial variations in the percentage of the population that believes that "global warming is happening." This effect is diminished in areas that have experienced more record low temperatures than record highs since 2005. Together, these results suggest that skepticism about climate change is driven partially by personal experiences; an accurate heuristic for local changes in climate identifies obstacles to communicating ongoing changes in climate to the public and how these communications might be improved.

  6. Study of locations’characteristics for stabilization of street vendors in Surakarta City

    Science.gov (United States)

    Rahayu, M. J.; Buchori, I.; Widjajanti, R.

    2018-01-01

    Street vendors are usually centered around particular areas where they have made adaptations based on their activities, instead of scattered all over the city. These locations tend to be close to street vendors’ primary activities and consumers, occupy the public lands, and are productive and accessible. The Municipality of Surakarta has managed the street vendors in the form of stabilization and relocation. In Surakarta, there are 24 areas used for stabilization of street vendors varying in characteristics and quantities. This study uses a spatial analysis aiming to explain the characteristics of locations used for stabilization of street vendors and to identify their physical condition and arrangement. Furthermore, all of the research results will be used as the criteria in choosing the new locations that are suitable for the street vendors’ characteristics and consumers’ preference. The results show that the locations are on the roadsides of the neighborhood, local, and secondary collector roads. The traffic conditions in the stabilization areas are ranging from the very busy until relatively busy level since they are close to activities for trade, education, recreation, offices, and settlements.

  7. Mutations of different molecular origins exhibit contrasting patterns of regional substitution rate variation.

    Directory of Open Access Journals (Sweden)

    Navin Elango

    2008-02-01

    Full Text Available Transitions at CpG dinucleotides, referred to as "CpG substitutions", are a major mutational input into vertebrate genomes and a leading cause of human genetic disease. The prevalence of CpG substitutions is due to their mutational origin, which is dependent on DNA methylation. In comparison, other single nucleotide substitutions (for example those occurring at GpC dinucleotides mainly arise from errors during DNA replication. Here we analyzed high quality BAC-based data from human, chimpanzee, and baboon to investigate regional variation of CpG substitution rates. We show that CpG substitutions occur approximately 15 times more frequently than other single nucleotide substitutions in primate genomes, and that they exhibit substantial regional variation. Patterns of CpG rate variation are consistent with differences in methylation level and susceptibility to subsequent deamination. In particular, we propose a "distance-decaying" hypothesis, positing that due to the molecular mechanism of a CpG substitution, rates are correlated with the stability of double-stranded DNA surrounding each CpG dinucleotide, and the effect of local DNA stability may decrease with distance from the CpG dinucleotide.Consistent with our "distance-decaying" hypothesis, rates of CpG substitution are strongly (negatively correlated with regional G+C content. The influence of G+C content decays as the distance from the target CpG site increases. We estimate that the influence of local G+C content extends up to 1,500 approximately 2,000 bps centered on each CpG site. We also show that the distance-decaying relationship persisted when we controlled for the effect of long-range homogeneity of nucleotide composition. GpC sites, in contrast, do not exhibit such "distance-decaying" relationship. Our results highlight an example of the distinctive properties of methylation-dependent substitutions versus substitutions mostly arising from errors during DNA replication. Furthermore

  8. Digital Natives: Creating Emergent Exhibitions through Digital Technologies

    DEFF Research Database (Denmark)

    Smith, Rachel Charlotte; Iversen, Ole Sejer; Dindler, Christian

    2011-01-01

    . In this way, digital technology can contribute to the creation of emergent exhibitions in which the exhibition is created in dialogue between audiences and the museum. We present experiences from a current research project, the Digital Natives exhibition, in which digital technology was designed......Digital Technology can support the creation of dialogical spaces in the museum, both playful and reflective, that allow audiences to engage in the ongoing construction and reproduction of cultural heritage creating novel connections between self and others and between past, present and future...... as an integral part of the exhibition to encourage dialogue between audiences and the exhibition materials and thereby investigate how the exhibition emerge as a result of this dialogic co-construction inside the exhibition space. In short, the opportunities offered by digital technologies prompts us to consider...

  9. RNaseT2 knockout rats exhibit hippocampal neuropathology and deficits in memory.

    Science.gov (United States)

    Sinkevicius, Kerstin W; Morrison, Thomas R; Kulkarni, Praveen; Cagliostro, Martha K Caffrey; Iriah, Sade; Malmberg, Samantha; Sabrick, Julia; Honeycutt, Jennifer A; Askew, Kim L; Trivedi, Malav; Ferris, Craig F

    2018-05-10

    RNASET2 deficiency in humans is associated with infant cystic leukoencephalopathy, which causes psychomotor impairment, spasticity, and epilepsy. A zebrafish mutant model suggests that loss of RNASET2 function leads to neurodegeneration due to the accumulation of non-degraded RNA in the lysosomes. The goal of this study was to characterize the first rodent model of RNASET2 deficiency. The brains of 3- and 12-month-old RNaseT2 knockout rats were studied using multiple magnetic resonance imaging modalities and behavioral tests. While T1 and T2 weighted images of RNaseT2 knockout rats exhibited no evidence of cystic lesions, the prefrontal cortex and hippocampal complex were enlarged in knockout animals. Diffusion weighted imaging showed altered anisotropy and putative gray matter changes in the hippocampal complex of the RNaseT2 knockout rats. Immunohistochemistry for glial fibrillary acidic protein (GFAP) showed the presence of hippocampal neuroinflammation. Decreased levels of lysosome-associated membrane protein 2 (LAMP2) and elevated acid phosphatase and β-N-Acetylglucosaminidase (NAG) activities indicated that the RNASET2 knockout rats likely had altered lysosomal function and potential defects in autophagy. Object recognition tests confirmed the RNaseT2 knockout rats exhibited memory deficits. However, the Barnes maze, and balance beam and rotarod tests, indicated there were no differences in spatial memory or motor impairments, respectively. Overall, patients with RNASET2 deficiency exhibited a more severe neurodegeneration phenotype than was observed in the RNaseT2 knockout rats. However, the vulnerability of the knockout rat hippocampus as evidenced by neuroinflammation, altered lysosomal function, and cognitive defects indicates this is still a useful in vivo model to study RNASET2 function. © 2018. Published by The Company of Biologists Ltd.

  10. Artefacts and the performance of an exhibition

    DEFF Research Database (Denmark)

    Svabo, Connie

    2008-01-01

    The article explores the role of mediating artefacts in children's encounters with a museum of natural history. Using actor network theory it explores how a specific artefact shapes the way users relate to exhibited objects and how the artefact guides users' movements in the exhibition....... The mediated performance of an exhibition is explored through an empirical case....

  11. The effect of cure conditions on the stability of cement waste forms after immersion in water

    International Nuclear Information System (INIS)

    Siskind, B.; Adams, J.W.; Clinton, J.H.; Piciulo, P.L.; McDaniel, K.

    1988-01-01

    We investigated the effects of curing conditions on the stability of cement-solidified ion-exchange resins after immersion in water. The test specimens consisted of partially depleted mixed-bed bead resins solidified in one of three vendor-supplied Portland I cement formulations, in a reference cement formulation, or in a gypsum-based binder formulation. We cured samples prepared using each formulation in sealed containers for periods of 7, 14, or 28 days as well as in air or with an accelerated heat cure prior to 90-day immersion in water. Two cement formulations exhibited apparent Portland-cement-like behavior, i.e., compressive strength increased or stabilized with increasing cure time. Two cement formulations exhibited behavior apparently unlike that of Portland cement, i.e., compressive strength decreased with increasing cure time. Such non-Portland-cement-like behavior is correlated with higher waste loadings. The gypsum-based formulation exhibited approximately constant compressive strength with cure time. Accelerated heat cures may not give compressive strengths representative of real-time cures. Some physical deterioration (cracking, spalling) of the waste form occurs during immersion

  12. The effect of cure conditions on the stability of cement waste forms after immersion in water

    International Nuclear Information System (INIS)

    Siskind, B.; Adams, J.W.; Clinton, J.H.; Piciulo, P.L.

    1988-01-01

    The authors investigated the effects of curing conditions on the stability of cement-solidified ion-exchange resins after immersion in water. The test specimens consisted of partially depleted mixed-bed bead resins solidified in one of three vendor-supplied Portland I cement formulations, in a reference cement formulation, or in a gypsum-based binder formulation. They cured samples prepared using each formulation in sealed containers for periods of 7, 14, or 28 days as well as in air or with an accelerated heat cure prior to 90-day immersion in water. Two cement formulations exhibited apparent Portland-cement-like behavior, i.e., compressive strength increased or stabilized with increasing cure time. Two cement formulations exhibited behavior apparently unlike that of Portland cement, i.e. compressive strength decreased with increasing cure time. Such non-Portland-cement-like behavior is correlated with higher waste loadings. The gypsum-based formulation exhibited approximately constant compressive strength with cure time. Accelerated heat cures may not give compressive strengths representative of real-time cures. Some physical deterioration (cracking, spalling) of the waste form occurs during immersion

  13. Characteristics of premixed flames stabilized in an axisymmetric curved-wall jet burner with tip modification

    KAUST Repository

    Kim, Daejoong

    2009-11-10

    The stabilization characteristics of premixed flames in an axisymmetric curved-wall jet burner have been experimentally investigated. This burner utilized the Coanda effect on top of a burner tip. The initially spherical burner tip was modified to a flat tip and a concave tip in order to improve flame stabilization by providing enough space for flow recirculation above the burner tip region. The flow characteristics have been visualized using a schlieren technique. Small-scale turbulence structure has been observed mainly in the interaction jet region (located downstream of the recirculation region) for large jet velocity (Reynolds number >11,500). An appreciable amount of air entrainment was exhibited from the half-angle of the jet spread, approximately 20. The averaged planar laser-induced fluorescence images of the flames for this large velocity demonstrated that the strong signal of OH radicals, representing reaction zones, existed in the recirculation zone, while it was weak in the interaction jet region due to intermittency and local extinction by the generation of small scale turbulence. The OH radical signals strengthened again in the merged jet region (downstream of the interaction jet region). In extreme cases of Reynolds number over 19,000, a unique flame exhibiting OH radicals only in the recirculation zone was observed for the concave tip. The flame stabilization has been mapped by varying jet velocity and equivalence ratio, and the result showed that the stabilization characteristics were improved appreciably from the initial spherical tip design, especially for rich mixtures. The flow fields measured by a laser Doppler velocimetry confirmed the existence of recirculation zone and the expansion of the recirculation zones for the modified tips. The temperature profile measured by a coherent anti-Stokes Raman spectroscopy exhibited an intermittent nature, especially near the recirculation zone.

  14. Soft X-ray spectroscopic investigations in experiments on Z-pinch stabilization

    International Nuclear Information System (INIS)

    Pikuz, S.A.; Skobelev, I.Yu.

    1996-01-01

    X-ray spectroscopic methods were used to investigate the spatial distribution of Z-pinch plasma parameters. Experiments were carried out on the GAEL pulse line generator in Ecole Polytechnique (France) with different types of load. Obtained results for the concentration of electrons and plasma temperature showed that higher plasma homogeneity was obtained in experiments with complex load. Spectrograms demonstrate the stabilization effect of the A1-jet. (orig.)

  15. Soft X-ray spectroscopic investigations in experiments on Z-pinch stabilization

    Energy Technology Data Exchange (ETDEWEB)

    Pikuz, S.A. [Rossijskaya Akademiya Nauk, Moscow (Russian Federation). Fizicheskij Inst.; Shelkovenko, T.A. [Rossijskaya Akademiya Nauk, Moscow (Russian Federation). Fizicheskij Inst.; Romanova, V.M. [Rossijskaya Akademiya Nauk, Moscow (Russian Federation). Fizicheskij Inst.; Etlicher, B. [Ecole Polytechnique, Palaseau (France). Lab. de Phys. des Mililux Ionises; Attelan, S. [Ecole Polytechnique, Palaseau (France). Lab. de Phys. des Mililux Ionises; Chuvatin, A.S. [Ecole Polytechnique, Palaseau (France). Lab. de Phys. des Mililux Ionises; Faenov, A.Ya. [MISDC VNIIFTRI, Moscow (Russian Federation); Skobelev, I.Yu. [MISDC VNIIFTRI, Moscow (Russian Federation)

    1996-04-01

    X-ray spectroscopic methods were used to investigate the spatial distribution of Z-pinch plasma parameters. Experiments were carried out on the GAEL pulse line generator in Ecole Polytechnique (France) with different types of load. Obtained results for the concentration of electrons and plasma temperature showed that higher plasma homogeneity was obtained in experiments with complex load. Spectrograms demonstrate the stabilization effect of the A1-jet. (orig.).

  16. A content-oriented model for science exhibit engineering

    DEFF Research Database (Denmark)

    Achiam, Marianne

    2013-01-01

    Recently, science museums have begun to review their educational purposes and redesign their pedagogies. At the most basic level, this entails accounting for the performance of individual exhibits, and indeed, in some cases, research indicates shortcomings in exhibit design: While often successful......: as a means to operationalize the link between exhibit features and visitor activities; and as a template to transform scientists’ practices in the research context into visitors’ activities in the exhibit context. The resulting model of science exhibit engineering is presented and exemplified, and its...... implications for science exhibit design are discussed at three levels: the design product, the design process, and the design methodology....

  17. Novel probabilistic models of spatial genetic ancestry with applications to stratification correction in genome-wide association studies.

    Science.gov (United States)

    Bhaskar, Anand; Javanmard, Adel; Courtade, Thomas A; Tse, David

    2017-03-15

    Genetic variation in human populations is influenced by geographic ancestry due to spatial locality in historical mating and migration patterns. Spatial population structure in genetic datasets has been traditionally analyzed using either model-free algorithms, such as principal components analysis (PCA) and multidimensional scaling, or using explicit spatial probabilistic models of allele frequency evolution. We develop a general probabilistic model and an associated inference algorithm that unify the model-based and data-driven approaches to visualizing and inferring population structure. Our spatial inference algorithm can also be effectively applied to the problem of population stratification in genome-wide association studies (GWAS), where hidden population structure can create fictitious associations when population ancestry is correlated with both the genotype and the trait. Our algorithm Geographic Ancestry Positioning (GAP) relates local genetic distances between samples to their spatial distances, and can be used for visually discerning population structure as well as accurately inferring the spatial origin of individuals on a two-dimensional continuum. On both simulated and several real datasets from diverse human populations, GAP exhibits substantially lower error in reconstructing spatial ancestry coordinates compared to PCA. We also develop an association test that uses the ancestry coordinates inferred by GAP to accurately account for ancestry-induced correlations in GWAS. Based on simulations and analysis of a dataset of 10 metabolic traits measured in a Northern Finland cohort, which is known to exhibit significant population structure, we find that our method has superior power to current approaches. Our software is available at https://github.com/anand-bhaskar/gap . abhaskar@stanford.edu or ajavanma@usc.edu. Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press. All rights reserved

  18. Hippocampus lesions induced deficits in social and spatial recognition in Octodon degus.

    Science.gov (United States)

    Uekita, Tomoko; Okanoya, Kazuo

    2011-06-01

    Previous studies of rodents reported that the hippocampus plays an important role in social behavior as well as spatial behavior. However, there are inconsistencies between reports of the effects of hippocampal lesions on social behavior. The present study sought to clarify the aspects of social behavior in which the hippocampus plays a role in the degu, Octodon degus, a social rodent. We examined the effects of hippocampal lesions on social behavior in the degu using familiar and novel partners. When placed in a familiar environment with a familiar partner after surgery, sham operation control (S.Cont) degus exhibited affinitive behavior longer compared with hippocampal lesioned (HPC) degus. In a novel environment, S.Cont degus exhibited longer aggressive behavior toward novel partners, and longer affinitive behavior with familiar partners compared with HPC degus. HPC degus did not show evidence of differentiation in social behavior, regardless of partner's novelty. The results of an anxiety test confirmed that these findings could not be attributed to changes in emotional state. We conducted an object-recognition test with the same subjects. HPC degus showed an impairment in spatial recognition but not object recognition. Taken together, these results suggest that the degu hippocampus plays an important role not only in spatial recognition but also social recognition. The changes in social behavior resulting from hippocampal lesions were interpreted as due to an impairment of social recognition rather than an impairment in novelty detection. Copyright © 2011 Elsevier B.V. All rights reserved.

  19. Gender dimorphism in aspartame-induced impairment of spatial cognition and insulin sensitivity.

    Science.gov (United States)

    Collison, Kate S; Makhoul, Nadine J; Zaidi, Marya Z; Saleh, Soad M; Andres, Bernard; Inglis, Angela; Al-Rabiah, Rana; Al-Mohanna, Futwan A

    2012-01-01

    Previous studies have linked aspartame consumption to impaired retention of learned behavior in rodents. Prenatal exposure to aspartame has also been shown to impair odor-associative learning in guinea pigs; and recently, aspartame-fed hyperlipidemic zebrafish exhibited weight gain, hyperglycemia and acute swimming defects. We therefore investigated the effects of chronic lifetime exposure to aspartame, commencing in utero, on changes in blood glucose parameters, spatial learning and memory in C57BL/6J mice. Morris Water Maze (MWM) testing was used to assess learning and memory, and a random-fed insulin tolerance test was performed to assess glucose homeostasis. Pearson correlation analysis was used to investigate the associations between body characteristics and MWM performance outcome variables. At 17 weeks of age, male aspartame-fed mice exhibited weight gain, elevated fasting glucose levels and decreased insulin sensitivity compared to controls (Pdifferent from controls. Reference memory during a probe test was affected in both genders, with the aspartame-fed mice spending significantly less time searching for the former location of the platform. Interestingly, the extent of visceral fat deposition correlated positively with non-spatial search strategies such as floating and thigmotaxis, and negatively with time spent in the target quadrant and swimming across the location of the escape platform. These data suggest that lifetime exposure to aspartame, commencing in utero, may affect spatial cognition and glucose homeostasis in C57BL/6J mice, particularly in males.

  20. Spatially uniform but temporally variable bacterioplankton in a semi-enclosed coastal area.

    Science.gov (United States)

    Meziti, Alexandra; Kormas, Konstantinos A; Moustaka-Gouni, Maria; Karayanni, Hera

    2015-07-01

    Studies focusing on the temporal and spatial dynamics of bacterioplankton communities within littoral areas undergoing direct influences from the coast are quite limited. In addition, they are more complicated to resolve compared to communities in the open ocean. In order to elucidate the effects of spatial vs. temporal variability on bacterial communities in a highly land-influenced semi-enclosed gulf, surface bacterioplankton communities from five coastal sites in Igoumenitsa Gulf (Ionian Sea, Greece) were analyzed over a nine-month period using 16S rDNA 454-pyrosequencing. Temporal differences were more pronounced than spatial ones, with lower diversity indices observed during the summer months. During winter and early spring, bacterial communities were dominated by SAR11 representatives, while this pattern changed in May when they were abruptly replaced by members of Flavobacteriales, Pseudomonadales, and Alteromonadales. Additionally, correlation analysis showed high negative correlations between the presence of SAR11 OTUs in relation to temperature and sunlight that might have driven, directly or indirectly, the disappearance of these OTUs in the summer months. The dominance of SAR11 during the winter months further supported the global distribution of the clade, not only in the open-sea, but also in coastal systems. This study revealed that specific bacteria exhibited distinct succession patterns in an anthropogenic-impacted coastal system. The major bacterioplankton component was represented by commonly found marine bacteria exhibiting seasonal dynamics, while freshwater and terrestrial-related phylotypes were absent. Copyright © 2015 Elsevier GmbH. All rights reserved.

  1. Gender dimorphism in aspartame-induced impairment of spatial cognition and insulin sensitivity.

    Directory of Open Access Journals (Sweden)

    Kate S Collison

    Full Text Available Previous studies have linked aspartame consumption to impaired retention of learned behavior in rodents. Prenatal exposure to aspartame has also been shown to impair odor-associative learning in guinea pigs; and recently, aspartame-fed hyperlipidemic zebrafish exhibited weight gain, hyperglycemia and acute swimming defects. We therefore investigated the effects of chronic lifetime exposure to aspartame, commencing in utero, on changes in blood glucose parameters, spatial learning and memory in C57BL/6J mice. Morris Water Maze (MWM testing was used to assess learning and memory, and a random-fed insulin tolerance test was performed to assess glucose homeostasis. Pearson correlation analysis was used to investigate the associations between body characteristics and MWM performance outcome variables. At 17 weeks of age, male aspartame-fed mice exhibited weight gain, elevated fasting glucose levels and decreased insulin sensitivity compared to controls (P<0.05. Females were less affected, but had significantly raised fasting glucose levels. During spatial learning trials in the MWM (acquisition training, the escape latencies of male aspartame-fed mice were consistently higher than controls, indicative of learning impairment. Thigmotactic behavior and time spent floating directionless was increased in aspartame mice, who also spent less time searching in the target quadrant of the maze (P<0.05. Spatial learning of female aspartame-fed mice was not significantly different from controls. Reference memory during a probe test was affected in both genders, with the aspartame-fed mice spending significantly less time searching for the former location of the platform. Interestingly, the extent of visceral fat deposition correlated positively with non-spatial search strategies such as floating and thigmotaxis, and negatively with time spent in the target quadrant and swimming across the location of the escape platform. These data suggest that lifetime

  2. France at CERN – Industrial exhibition

    CERN Multimedia

    FP Department

    2012-01-01

    Industrial Exhibition Administration Building Bldg 61 – 1st Floor Tuesday 27 March: 9 a.m. – 5.30 p.m. Wednesday 28 March: 9 a.m. – 2 p.m.   About thirty French companies are presenting their latest technological advances during the industrial exhibition "France at CERN", featuring products and technologies specifically related to CERN activities. Individual B2B meetings can be organized with the sales and technical representatives of participating firms and will take place at either the companies’ exhibition stands or in conference rooms in the Main Building. Individuals wishing to make contact with one or more companies must use the contact details available from each secretariat of department or by using this link. B2B meetings will be coordinated by UBIFRANCE. You will also find the list of exhibiting and participating companies online here. This event is sponsored by the French subsidiary of RS Components, the most important distri...

  3. Structure, stability and electrochromic properties of polyaniline film covalently bonded to indium tin oxide substrate

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Wenzhi, E-mail: zhangwz@xatu.edu.cn [Key Laboratory for Photoelectric Functional Materials and Devices of Shaanxi Province, School of Materials and Chemical Engineering, Xi’an Technological University, Xi’an 710021 (China); Ju, Wenxing; Wu, Xinming; Wang, Yan; Wang, Qiguan; Zhou, Hongwei; Wang, Sumin [Key Laboratory for Photoelectric Functional Materials and Devices of Shaanxi Province, School of Materials and Chemical Engineering, Xi’an Technological University, Xi’an 710021 (China); Hu, Chenglong [Key Laboratory of Optoelectronic Chemical Materials and Devices of Ministry of Education, School of Chemistry and Environmental Engineering, Jianghan University, Wuhan 430056 (China)

    2016-03-30

    Graphical abstract: A chemical bonding approach was proposed to prepare the PANI film covalently bonded to ITO substrate and the film exhibited high electrochemical activities and stability compared with that obtained by conventional film-forming approach. - Highlights: • The PANI film covalently bonded to ITO substrate was prepared using ABPA as modifier. • The oxidative potentials of the obtained PANI film were decreased. • The obtained PANI film exhibits high electrochemical activities and stability. - Abstract: Indium tin oxide (ITO) substrate was modified with 4-aminobenzylphosphonic acid (ABPA), and then the polyaniline (PANI) film covalently bonded to ITO substrate was prepared by the chemical oxidation polymerization. X-ray photoelectron spectroscopy (XPS), attenuated total reflection infrared (ATR-IR) spectroscopy, and atomic force microscopy (AFM) measurements demonstrated that chemical binding was formed between PANI and ABPA-modified ITO surface, and the maximum thickness of PANI layer is about 30 nm. The adhesive strength of PANI film on ITO substrate was tested by sonication. It was found that the film formed on the modified ITO exhibited a much better stability than that on bare one. Cyclic voltammetry (CV) and UV–vis spectroscopy measurements indicated that the oxidative potentials of PANI film on ABPA-modified ITO substrate were decreased and the film exhibited high electrochemical activities. Moreover, the optical contrast increased from 0.58 for PANI film (without ultrasound) to 1.06 for PANI film (after ultrasound for 60 min), which had an over 83% enhancement. The coloration time was 20.8 s, while the bleaching time was 19.5 s. The increase of electrochromic switching time was due to the lower ion diffusion coefficient of the large cation of (C{sub 4}H{sub 9}){sub 4}N{sup +} under the positive and negative potentials as comparison with the small Li{sup +} ion.

  4. Spatial and temporal heterogeneity of infectious hematopoietic necrosis virus in Pacific Northwest salmonids

    Science.gov (United States)

    Breyta, Rachel; Black, Allison; Kaufman, John; Kurath, Gael

    2016-01-01

    The aquatic rhaboviral pathogen infectious hematopoietic necrosis virus (IHNV) causes acute disease in juvenile fish of a number of populations of Pacific salmonid species. Heavily managed in both marine and freshwater environments, these fish species are cultured during the juvenile stage in freshwater conservation hatcheries, where IHNV is one of the top three infectious diseases that cause serious morbidity and mortality. Therefore, a comprehensive study of viral genetic surveillance data representing 2590 field isolates collected between 1958 and 2014 was conducted to determine the spatial and temporal patterns of IHNV in the Pacific Northwest of the contiguous United States. Prevalence of infection varied over time, fluctuating over a rough 5–7 year cycle. The genetic analysis revealed numerous subgroups of IHNV, each of which exhibited spatial heterogeneity. Within all subgroups, dominant genetic types were apparent, though the temporal patterns of emergence of these types varied among subgroups. Finally, the affinity or fidelity of subgroups to specific host species also varied, where UC subgroup viruses exhibited a more generalist profile and all other subgroups exhibited a specialist profile. These complex patterns are likely synergistically driven by numerous ecological, pathobiological, and anthropogenic factors. Since only a few anthropogenic factors are candidates for managed intervention aimed at improving the health of threatened or endangered salmonid fish populations, determining the relative impact of these factors is a high priority for future studies.

  5. Temporary and Travelling Exhibitions. Museums and Monuments, X.

    Science.gov (United States)

    Daifuku, Hiroshi; And Others

    The permanent exhibition, the most typical form of museum exhibition, has failed to attract repeated visitation, since visitors quickly become familiar with the objects shown. The temporary exhibition evolved as a result for the need of repeated visitation. The temporary exhibition, set up for a period of one to six months, introduces fresh…

  6. Chaos induced by breakup of waves in a spatial epidemic model with nonlinear incidence rate

    International Nuclear Information System (INIS)

    Sun, Gui-Quan; Jin, Zhen; Liu, Quan-Xing; Li, Li

    2008-01-01

    Spatial epidemiology is the study of spatial variation in disease risk or incidence, including the spatial patterns of the population. The spread of diseases in human populations can exhibit large scale patterns, underlining the need for spatially explicit approaches. In this paper, the spatiotemporal complexity of a spatial epidemic model with nonlinear incidence rate, which includes the behavioral changes and crowding effect of the infective individuals, is investigated. Based on both theoretical analysis and computer simulations, we find out when, under the parameters which can guarantee a stable limit cycle in the non-spatial model, spiral and target waves can emerge. Moreover, two different kinds of breakup of waves are shown. Specifically, the breakup of spiral waves is from the core and the breakup of target waves is from the far-field, and both kinds of waves become irregular patterns at last. Our results reveal that the spatiotemporal chaos is induced by the breakup of waves. The results obtained confirm that diffusion can form spiral waves, target waves or spatial chaos of high population density, which enrich the findings of spatiotemporal dynamics in the epidemic model

  7. Stability and enzyme inhibition activities of au nanoparticles using an aqueous extract of clove as a reducing and stabilizing agent

    International Nuclear Information System (INIS)

    Hameed, A.; Khan, I.; Naz, S.S.; Islam, N.U.

    2014-01-01

    Gold nanoparticles (AuNPs) were synthesized in one pot using aqueous extract of clove buds (CB) to reduce HAuCl/sub 4/ and stabilize gold in its atomic form at room temperature. To determine the potential of gold nanoparticles with clove buds (AuCB) for in vivo applications, the stability of the nanoparticles was explored as a function of temperature, pH and salt concentration. The suspensions were found to be stable for salt concentrations up to 1 mol/L, temperatures of up to 100 degree C and a pH range of 2-13. Our results indicate that CB exhibited comparable activities to standards of urease and carbonic anhydrase, but its conjugation to Au knocks out the enzyme inhibition activity by about two times. In case of xanthine oxidase activity, CB and its gold Au bio-conjugates (AuCB) are found to be absolutely inactive. (author)

  8. The Stability, Sustained Release and Cellular Antioxidant Activity of Curcumin Nanoliposomes

    OpenAIRE

    Chen, Xing; Zou, Li-Qiang; Niu, Jing; Liu, Wei; Peng, Sheng-Feng; Liu, Cheng-Mei

    2015-01-01

    Curcumin is a multifunctional and natural agent considered to be pharmacologically safe. However, its application in the food and medical industry is greatly limited by its poor water solubility, physicochemical instability and inadequate bioavailability. Nanoliposome encapsulation could significantly enhance the solubility and stability of curcumin. Curcumin nanoliposomes exhibited good physicochemical properties (entrapment efficiency = 57.1, particle size = 68.1 nm, polydispersity index = ...

  9. High and low schizotypal female subjects do not differ in spatial memory abilities in a virtual reality task.

    Science.gov (United States)

    García-Montes, José Manuel; Noguera, Carmen; Alvarez, Dolores; Ruiz, Marina; Cimadevilla Redondo, José Manuel

    2014-01-01

    Schizotypy is a psychological construct related to schizophrenia. The exact relationship between both entities is not clear. In recent years, schizophrenia has been associated with hippocampal abnormalities and spatial memory problems. The aim of this study was to determine possible links between high schizotypy (HS) and low schizotypy (LS) and spatial abilities, using virtual reality tasks. We hypothesised that the HS group would exhibit a lower performance in spatial memory tasks than the LS group. Two groups of female students were formed according to their score on the ESQUIZO-Q-A questionnaire. HS and LS subjects were tested on two different tasks: the Boxes Room task, a spatial memory task sensitive to hippocampal alterations and a spatial recognition task. Data showed that both groups mastered both tasks. Groups differed in personality features but not in spatial performance. These results provide valuable information about the schizotypy-schizophrenia connections. Schizotypal subjects are not impaired on spatial cognition and, accordingly, the schizotypy-schizophrenia relationship is not straightforward.

  10. Stability and heating of a poloidal divertor tokamak

    Energy Technology Data Exchange (ETDEWEB)

    Biddle, A. P.; Dexter, R. N.; Holly, D. T.; Lipschultz, B.; Osborne, T. H.; Prager, S. C.; Shepard, D.A., Sprott, J.C.; Witherspoon, F. D.

    1980-06-01

    Five experimental studies - two stability and three heating investigations - have been carried out on Tokapole II, a Tokamak with a four node poloidal divertor. First, discharges have been attained with safety factor q as low as 0.6 over most of the column without degradation of confinement, and correlation of helical instability onset with current profile shape is being studied. Second, the axisymmetric instability has been investigated in detail for various noncircular cross-sectional shapes, and results have been compared with a numerical stability code adapted to the Tokapole machine. Third, application of high power fast wave ion cyclotron resonance heating doubles the ion temperature and permits observation of heating as a function of harmonic number and spatial location of the resonance. Fourth, low power shear Alfven wave propagation is underway to test the applicability of this heating method to tokamaks. Fifth, preionization by electron cyclotron heating has been employed to reduce the startup loop voltage by approx. 60%.

  11. Early structure of LPG partially premixed conically stabilized flames

    KAUST Repository

    Elbaz, Ayman M.

    2013-01-01

    This paper presents experimental investigation of LPG partially premixed turbulent flames stabilized within a conical nozzle burner under constant degree of partial premixing. The stability limits and mean flame structure are presented based on the mean gas temperature and the concentration of CO, O 2, NO, and HC at the flame early region of reaction. The investigation covered the influence of the nozzle cone angle, the jet exit velocity and the jet equivalence ratio. The stability results show that the flames with cone are more stable than those without cone. For conical stabilized flames, the stability results exhibit three different sensitivity regions between the jet velocity and equivalence ratio. The inflame measurements prove that the flame stability could be attributed to the triple flame structure at the flame leading edge. The data show that the triple flame structure is influenced by cone angle, the jet velocity and the equivalence ratio. The flame is believed to be controlled by the recirculation flow inside the cone. Increasing the cone angle induced higher air entrainment to the reaction zone as depicted by a higher O 2 concentration within the flame leading edge. Increasing the jet velocity to a certain limit enhances the intensity of combustion at the flame leading edge, while excessive increase in jet velocity reduces this intensity. At a fixed jet velocity the higher the equivalence ratio, the higher the amount of fuel diffused and engulfed to the reaction zone, the more delay of the combustion completion and the higher the emission concentrations of the flame. © 2012 Elsevier Inc.

  12. Earth System Stability Through Geologic Time

    Science.gov (United States)

    Rothman, D.; Bowring, S. A.

    2015-12-01

    Five times in the past 500 million years, mass extinctions haveresulted in the loss of greater than three-fourths of living species.Each of these events is associated with significant environmentalchange recorded in the carbon-isotopic composition of sedimentaryrocks. There are also many such environmental events in the geologicrecord that are not associated with mass extinctions. What makes themdifferent? Two factors appear important: the size of theenvironmental perturbation, and the time scale over which it occurs.We show that the natural perturbations of Earth's carbon cycle during thepast 500 million years exhibit a characteristic rate of change overtwo orders of magnitude in time scale. This characteristic rate isconsistent with the maximum rate that limits quasistatic (i.e., nearsteady-state) evolution of the carbon cycle. We identify this rate withmarginal stability, and show that mass extinctions occur on the fast,unstable side of the stability boundary. These results suggest thatthe great extinction events of the geologic past, and potentially a"sixth extinction" associated with modern environmental change, arecharacterized by common mechanisms of instability.

  13. CERN Industrials Exhibitions - Over 30 Years of Tradition

    CERN Multimedia

    2001-01-01

    Industrial exhibitions have been part of the CERN landscape for 33 years. At least once each year several companies from the same country come to CERN to present their products and services. Now, a new scheme of one-day visits is giving potential exhibitors at CERN a lighter option. The United Kingdom inaugurated the Industrial Exhibitions in 1968, and it wasn't till 1971 that other countries staged exhibitions at CERN. This photo was taken in 1969, at the second British exhibition, where 16 companies were present. Four years after joining CERN, Poland inaugurated its first exhibition at CERN in 1995 in the presence of the former Director-General Chris Llewellyn-Smith. Almost all the Member States have held industrial exhibitions at the Organization. May '68 wasn't only revolutionary in Paris. For the very first time, an industrial exhibition took place at CERN. Great Britain was first to come with eight companies and remains until this day the most devoted country to the programme with 17 exhibitions and ...

  14. Surface profile gradient in amorphous Ta{sub 2}O{sub 5} semi conductive layers regulates nanoscale electric current stability

    Energy Technology Data Exchange (ETDEWEB)

    Cefalas, A.C., E-mail: ccefalas@eie.gr [National Hellenic Research Foundation, Theoretical and Physical Chemistry Institute, 48 Vassileos Constantinou Avenue, Athens 11635 (Greece); Kollia, Z.; Spyropoulos-Antonakakis, N.; Gavriil, V. [National Hellenic Research Foundation, Theoretical and Physical Chemistry Institute, 48 Vassileos Constantinou Avenue, Athens 11635 (Greece); Christofilos, D.; Kourouklis, G. [Physics Division, School of Technology, Aristotle University of Thessaloniki, Thessaloniki 54124 (Greece); Semashko, V.V.; Pavlov, V. [Kazan Federal University, Institute of Physics, 18 Kremljovskaja str., Kazan 420008 (Russian Federation); Sarantopoulou, E. [National Hellenic Research Foundation, Theoretical and Physical Chemistry Institute, 48 Vassileos Constantinou Avenue, Athens 11635 (Greece); Kazan Federal University, Institute of Physics, 18 Kremljovskaja str., Kazan 420008 (Russian Federation)

    2017-02-28

    Highlights: • The work links the surface morphology of amorphous semiconductors with both their electric-thermal properties and current stability at the nanoscale (<1 μm). • Measured high correlation value between surface morphological spatial gradient and conductive electron energy spatial gradient or thermal gradient. • Unidirectional current stability is associated with asymmetric nanodomains along nanosize conductive paths. • Bidirectional current stability is inherent with either long conductive paths or nanosize conductive paths along symmetric nanodomains. • Conclusion: Surface design improves current stability across nanoelectonic junctions. - Abstract: A link between the morphological characteristics and the electric properties of amorphous layers is established by means of atomic, conductive, electrostatic force and thermal scanning microscopy. Using amorphous Ta{sub 2}O{sub 5} (a-Ta{sub 2}O{sub 5}) semiconductive layer, it is found that surface profile gradients (morphological gradient), are highly correlated to both the electron energy gradient of trapped electrons in interactive Coulombic sites and the thermal gradient along conductive paths and thus thermal and electric properties are correlated with surface morphology at the nanoscale. Furthermore, morphological and electron energy gradients along opposite conductive paths of electrons intrinsically impose a current stability anisotropy. For either long conductive paths (L > 1 μm) or along symmetric nanodomains, current stability for both positive and negative currents i is demonstrated. On the contrary, for short conductive paths along non-symmetric nanodomains, the set of independent variables (L, i) is spanned by two current stability/intability loci. One locus specifies a stable state for negative currents, while the other locus also describes a stable state for positive currents.

  15. GIS-Based Evaluation of Spatial Interactions by Geographic Disproportionality of Industrial Diversity

    Directory of Open Access Journals (Sweden)

    Jemyung Lee

    2017-11-01

    Full Text Available Diversity of regional industry is regarded as a key factor for regional development, as it has a positive relationship with economic stability, which attracts population. This paper focuses on how the spatial imbalance of industrial diversity contributes to the population change caused by inter-regional migration. This paper introduces a spatial interaction model for the Geographic Information System (GIS-based simulation of the spatial interactions to evaluate the demographic attraction force. The proposed model adopts the notions of gravity, entropy, and virtual work. An industrial classification by profit level is introduced and its diversity is quantified with the entropy of information theory. The introduced model is applied to the cases of 207 regions in South Korea. Spatial interactions are simulated with an optimized model and their resultant forces, the demographic attraction forces, are compared with observed net migration for verification. The results show that the evaluated attraction forces from industrial diversity have a very significant, positive, and moderate relationship with net migration, while other conventional factors of industry, population, economy, and the job market do not. This paper concludes that the geographical quality of industrial diversity has positive and significant effects on population change by migration.

  16. Stability Analysis of a Reaction-Diffusion System Modeling Atherogenesis

    KAUST Repository

    Ibragimov, Akif

    2010-01-01

    This paper presents a linear, asymptotic stability analysis for a reaction-diffusionconvection system modeling atherogenesis, the initiation of atherosclerosis, as an inflammatory instability. Motivated by the disease paradigm articulated by Ross, atherogenesis is viewed as an inflammatory spiral with a positive feedback loop involving key cellular and chemical species interacting and reacting within the intimal layer of muscular arteries. The inflammatory spiral is initiated as an instability from a healthy state which is defined to be an equilibrium state devoid of certain key inflammatory markers. Disease initiation is studied through a linear, asymptotic stability analysis of a healthy equilibrium state. Various theorems are proved, giving conditions on system parameters guaranteeing stability of the health state, and a general framework is developed for constructing perturbations from a healthy state that exhibit blow-up, which are interpreted as corresponding to disease initiation. The analysis reveals key features that arterial geometry, antioxidant levels, and the source of inflammatory components (through coupled third-kind boundary conditions or through body sources) play in disease initiation. © 2010 Society for Industrial and Applied Mathematics.

  17. Resilience and stability in bird guilds across tropical countryside

    Science.gov (United States)

    Karp, Daniel S.; Ziv, Guy; Zook, Jim; Ehrlich, Paul R.; Daily, Gretchen C.

    2011-01-01

    The consequences of biodiversity decline in intensified agricultural landscapes hinge on surviving biotic assemblages. Maintaining crucial ecosystem processes and services requires resilience to natural and anthropogenic disturbances. However, the resilience and stability of surviving biological communities remain poorly quantified. From a 10-y dataset comprising 2,880 bird censuses across a land-use gradient, we present three key findings concerning the resilience and stability of Costa Rican bird communities. First, seed dispersing, insect eating, and pollinating guilds were more resilient to low-intensity land use than high-intensity land use. Compared with forest assemblages, bird abundance, species richness, and diversity were all ∼15% lower in low-intensity land use and ∼50% lower in high-intensity land use. Second, patterns in species richness generally correlated with patterns in stability: guilds exhibited less variation in abundance in low-intensity land use than in high-intensity land use. Finally, interspecific differences in reaction to environmental change (response diversity) and possibly the portfolio effect, but not negative covariance of species abundances, conferred resilience and stability. These findings point to the changes needed in agricultural production practices in the tropics to better sustain bird communities and, possibly, the functional and service roles that they play. PMID:22160726

  18. Memory and Mourning: An Exhibit History

    Science.gov (United States)

    Eberle, Scott G.

    2005-01-01

    Mounted by the Strong Museum in Rochester, New York, in 1993, and traveling nationally thereafter, the exhibit Memory and Mourning provided historical and contemporary perspectives to help museum guests explore their own reactions to loss and grief. In the process the exhibit's development team encountered a range of philosophical, historical,…

  19. Effect of virtual mass on the characteristics and the numerical stability in two-phase flows

    International Nuclear Information System (INIS)

    No, H.C.; Kazimi, M.S.

    1981-04-01

    It is known that the typical six equation two-fluid model of the two-phase flow possesses complex characteristics, exhibits unbounded instabilities in the short-wavelength limit and constitutes an ill-posed initial value problem. Among the suggestions to overcome these difficulties, one model for the virtual mass force terms were studied here, because the virtual mass represents real physical effects to accomplish the dissipation for numerical stability. It was found that the virtual mass has a profound effect upon the mathematical characteristic and numerical stability. Here a quantitative bound on the coefficient of the virtual mass terms was suggested for mathematical hyperbolicity and numerical stability. It was concluded that the finite difference scheme with the virtual mass model is restricted only by the convective stability conditions with the above suggested value

  20. Incorporating Human Movement Behavior into the Analysis of Spatially Distributed Infrastructure.

    Directory of Open Access Journals (Sweden)

    Lihua Wu

    Full Text Available For the first time in human history, the majority of the world's population resides in urban areas. Therefore, city managers are faced with new challenges related to the efficiency, equity and quality of the supply of resources, such as water, food and energy. Infrastructure in a city can be viewed as service points providing resources. These service points function together as a spatially collaborative system to serve an increasing population. To study the spatial collaboration among service points, we propose a shared network according to human's collective movement and resource usage based on data usage detail records (UDRs from the cellular network in a city in western China. This network is shown to be not scale-free, but exhibits an interesting triangular property governed by two types of nodes with very different link patterns. Surprisingly, this feature is consistent with the urban-rural dualistic context of the city. Another feature of the shared network is that it consists of several spatially separated communities that characterize local people's active zones but do not completely overlap with administrative areas. According to these features, we propose the incorporation of human movement into infrastructure classification. The presence of well-defined spatially separated clusters confirms the effectiveness of this approach. In this paper, our findings reveal the spatial structure inside a city, and the proposed approach provides a new perspective on integrating human movement into the study of a spatially distributed system.

  1. Incorporating Human Movement Behavior into the Analysis of Spatially Distributed Infrastructure.

    Science.gov (United States)

    Wu, Lihua; Leung, Henry; Jiang, Hao; Zheng, Hong; Ma, Li

    2016-01-01

    For the first time in human history, the majority of the world's population resides in urban areas. Therefore, city managers are faced with new challenges related to the efficiency, equity and quality of the supply of resources, such as water, food and energy. Infrastructure in a city can be viewed as service points providing resources. These service points function together as a spatially collaborative system to serve an increasing population. To study the spatial collaboration among service points, we propose a shared network according to human's collective movement and resource usage based on data usage detail records (UDRs) from the cellular network in a city in western China. This network is shown to be not scale-free, but exhibits an interesting triangular property governed by two types of nodes with very different link patterns. Surprisingly, this feature is consistent with the urban-rural dualistic context of the city. Another feature of the shared network is that it consists of several spatially separated communities that characterize local people's active zones but do not completely overlap with administrative areas. According to these features, we propose the incorporation of human movement into infrastructure classification. The presence of well-defined spatially separated clusters confirms the effectiveness of this approach. In this paper, our findings reveal the spatial structure inside a city, and the proposed approach provides a new perspective on integrating human movement into the study of a spatially distributed system.

  2. Induced polarization for characterizing and monitoring soil stabilization processes

    Science.gov (United States)

    Saneiyan, S.; Ntarlagiannis, D.; Werkema, D. D., Jr.

    2017-12-01

    Soil stabilization is critical in addressing engineering problems related to building foundation support, road construction and soil erosion among others. To increase soil strength, the stiffness of the soil is enhanced through injection/precipitation of a chemical agents or minerals. Methods such as cement injection and microbial induced carbonate precipitation (MICP) are commonly applied. Verification of a successful soil stabilization project is often challenging as treatment areas are spatially extensive and invasive sampling is expensive, time consuming and limited to sporadic points at discrete times. The geophysical method, complex conductivity (CC), is sensitive to mineral surface properties, hence a promising method to monitor soil stabilization projects. Previous laboratory work has established the sensitivity of CC on MICP processes. We performed a MICP soil stabilization projects and collected CC data for the duration of the treatment (15 days). Subsurface images show small, but very clear changes, in the area of MICP treatment; the changes observed fully agree with the bio-geochemical monitoring, and previous laboratory experiments. Our results strongly suggest that CC is sensitive to field MICP treatments. Finally, our results show that good quality data alone are not adequate for the correct interpretation of field CC data, at least when the signals are low. Informed data processing routines and the inverse modeling parameters are required to produce optimal results.

  3. An Ecohydrological Approach to the Resiliency and Stability of Ecosystems

    Science.gov (United States)

    Peña Alzate, S.; Canon Barriga, J. E.

    2013-12-01

    We introduce a simplified ecohydrological model to quantitatively assess the resiliency and stability of ecosystems. The proposed model couples a hydrological soil moisture balance with a set of spatiotemporal dynamics of systems and agent-based algorithms to represent the interactions among several plant populations in a gridded area under different water, soil and temperature constraints. The model also allows disturbances, representing mostly the effects of deforestation practices. The simulated ecosystem, composed by a set of plant populations, includes allometric rules (i.e., power laws for generational and reproductive times, linear approximations for water and temperature gains, losses and optimal values and a set of intra and interspecific interaction rules based on high, optimal and low competition responses among the populations). Disturbances are determined by a clearance of populations in a defined area within the model's domain. The effects of climate variability can be also incorporated through precipitation and temperature time series that exhibit trends and heteroskedasticity. Resiliency and stability are calculated with modified indices that are used in hydrology, in this case to determine the ability of the ecosystem to recover from a disturbance. The model represents different types of plant phenotypes showing exponential growth in the first steps of the simulations. The indices, evaluated on each population and over the structure of the entire ecosystem, show how different populations respond differently to disturbances, following behaviors similar to those expected in nature, like high reproduction rates on gregarious plants with short generation times, and low densities in plants with high generations times. The selection of plant populations was mainly focused on the concept of biodiversity with emphasis on tropical regions. The model can represent the spatial and temporal succession of the ecosystem after being disturbed. The model also

  4. Effect of dielectric layers on device stability of pentacene-based field-effect transistors.

    Science.gov (United States)

    Di, Chong-an; Yu, Gui; Liu, Yunqi; Guo, Yunlong; Sun, Xiangnan; Zheng, Jian; Wen, Yugeng; Wang, Ying; Wu, Weiping; Zhu, Daoben

    2009-09-07

    We report stable organic field-effect transistors (OFETs) based on pentacene. It was found that device stability strongly depends on the dielectric layer. Pentacene thin-film transistors based on the bare or polystyrene-modified SiO(2) gate dielectrics exhibit excellent electrical stabilities. In contrast, the devices with the octadecyltrichlorosilane (OTS)-treated SiO(2) dielectric layer showed the worst stabilities. The effects of the different dielectrics on the device stabilities were investigated. We found that the surface energy of the gate dielectric plays a crucial role in determining the stability of the pentacene thin film, device performance and degradation of electrical properties. Pentacene aggregation, phase transfer and film morphology are also important factors that influence the device stability of pentacene devices. As a result of the surface energy mismatch between the dielectric layer and organic semiconductor, the electronic performance was degraded. Moreover, when pentacene was deposited on the OTS-treated SiO(2) dielectric layer with very low surface energy, pentacene aggregation occurred and resulted in a dramatic decrease of device performance. These results demonstrated that the stable OFETs could be obtained by using pentacene as a semiconductor layer.

  5. Aging effect on step adjustments and stability control in visually perturbed gait initiation.

    Science.gov (United States)

    Sun, Ruopeng; Cui, Chuyi; Shea, John B

    2017-10-01

    Gait adaptability is essential for fall avoidance during locomotion. It requires the ability to rapidly inhibit original motor planning, select and execute alternative motor commands, while also maintaining the stability of locomotion. This study investigated the aging effect on gait adaptability and dynamic stability control during a visually perturbed gait initiation task. A novel approach was used such that the anticipatory postural adjustment (APA) during gait initiation were used to trigger the unpredictable relocation of a foot-size stepping target. Participants (10 young adults and 10 older adults) completed visually perturbed gait initiation in three adjustment timing conditions (early, intermediate, late; all extracted from the stereotypical APA pattern) and two adjustment direction conditions (medial, lateral). Stepping accuracy, foot rotation at landing, and Margin of Dynamic Stability (MDS) were analyzed and compared across test conditions and groups using a linear mixed model. Stepping accuracy decreased as a function of adjustment timing as well as stepping direction, with older subjects exhibited a significantly greater undershoot in foot placement to late lateral stepping. Late adjustment also elicited a reaching-like movement (i.e. foot rotation prior to landing in order to step on the target), regardless of stepping direction. MDS measures in the medial-lateral and anterior-posterior direction revealed both young and older adults exhibited reduced stability in the adjustment step and subsequent steps. However, young adults returned to stable gait faster than older adults. These findings could be useful for future study of screening deficits in gait adaptability and preventing falls. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. Damage Spreading in Spatial and Small-world Random Boolean Networks

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Qiming [Fermilab; Teuscher, Christof [Portland State U.

    2014-02-18

    The study of the response of complex dynamical social, biological, or technological networks to external perturbations has numerous applications. Random Boolean Networks (RBNs) are commonly used a simple generic model for certain dynamics of complex systems. Traditionally, RBNs are interconnected randomly and without considering any spatial extension and arrangement of the links and nodes. However, most real-world networks are spatially extended and arranged with regular, power-law, small-world, or other non-random connections. Here we explore the RBN network topology between extreme local connections, random small-world, and pure random networks, and study the damage spreading with small perturbations. We find that spatially local connections change the scaling of the relevant component at very low connectivities ($\\bar{K} \\ll 1$) and that the critical connectivity of stability $K_s$ changes compared to random networks. At higher $\\bar{K}$, this scaling remains unchanged. We also show that the relevant component of spatially local networks scales with a power-law as the system size N increases, but with a different exponent for local and small-world networks. The scaling behaviors are obtained by finite-size scaling. We further investigate the wiring cost of the networks. From an engineering perspective, our new findings provide the key design trade-offs between damage spreading (robustness), the network's wiring cost, and the network's communication characteristics.

  7. Spatial adjustments of mountain channels to changes in the sediment supply regime

    Science.gov (United States)

    Elgueta, M. A.; Hassan, M. A.; von Flotow, C. M.

    2012-12-01

    Sediment supply is a key controlling factor in bed morphology and sediment mobility. Under a low supply regime, bed structuring develops and reduces sediment mobility. Under high supply, structuring is suppressed and the bed exhibits patchiness. This study examines the spatial response of a mountain stream channel to changes in the sediment supply regime. To achieve this goal, a flume experiment was conducted in the Mountain Channel Hydraulic Experimental Laboratory at the University of British Columbia. An 18 meter long, one meter wide flume, with a slope of three percent was used. Seven continuous runs were conducted. Each of them lasted 40 hours, under constant flow and different sediment supply regimes, which included no feed, constant feed and episodic supply. In each run, bed elevation, bed grain size distribution, flow resistance, sediment mobility and degree of armoring were determined. Flume results were compared to field data from a 600 meter channel reach that exhibits rapid, riffle-pool and step-pool morphology in UBC Malcolm Knapp Research Forest. The study gave the possibility to analyze in detail the spatial adjustment of a mountain channel to changes in the sediment supply regime, including episodic inputs.

  8. Enhanced Physical Stability of Amorphous Drug Formulations via Dry Polymer Coating.

    Science.gov (United States)

    Capece, Maxx; Davé, Rajesh

    2015-06-01

    Although amorphous solid drug formulations may be advantageous for enhancing the bioavailability of poorly soluble active pharmaceutical ingredients, they exhibit poor physical stability and undergo recrystallization. To address this limitation, this study investigates stability issues associated with amorphous solids through analysis of the crystallization behavior for acetaminophen (APAP), known as a fast crystallizer, using a modified form of the Avrami equation that kinetically models both surface and bulk crystallization. It is found that surface-enhanced crystallization, occurring faster at the free surface than in the bulk, is the major impediment to the stability of amorphous APAP. It is hypothesized that a novel use of a dry-polymer-coating process referred to as mechanical-dry-polymer-coating may be used to inhibit surface crystallization and enhance stability. The proposed process, which is examined, simultaneously mills and coats amorphous solids with polymer, while avoiding solvents or solutions, which may otherwise cause stability or crystallization issues during coating. It is shown that solid dispersions of APAP (64% loading) with a small particle size (28 μm) could be prepared and coated with the polymer, carnauba wax, in a vibratory ball mill. The resulting amorphous solid was found to have excellent stability as a result of inhibition of surface crystallization. © 2015 Wiley Periodicals, Inc. and the American Pharmacists Association.

  9. CERN exhibition a big hit in Bulgaria

    CERN Multimedia

    2005-01-01

    The first CERN exhibition in Bulgaria attracted many visitors. In the first ever CERN exhibition to be held in Bulgaria, over 1,400 visitors, many of them students and young physicists, visited the 10-day event in Sofia. The CERN mini-exhibition took place at the National Earth and Mankind Museum between 8 and 17 November. Permanently staffed by young physicists from Sofia University, there were exhibits on display about research activities at CERN, as well as four additional posters describing Bulgaria's participation. The inauguration took place on the morning of 8 November in the presence of the Vice-Minister for Science and Education, Mrs. Vanya Dobreva, and some 200 guests. A series of short speeches were followed by a visit to the exhibition. CERN's representative at the event, Ray Lewis, was then asked by Professor Matey Mateev, President of the Union of Physicists in Bulgaria, to say a few words on behalf of the Organization. Numerous journalists were also present at the inauguration. A painting enti...

  10. CERN’s travelling exhibition goes to Austria

    CERN Multimedia

    Mélissa Lanaro

    2011-01-01

    Since April 2009 CERN’s travelling exhibition has been touring through some of the Organization's Member States. After Italy and Denmark it has been on show since February at Austria’s Hartberg Ökopark, a very popular science museum situated some one hundred kilometres from Vienna. To coincide with the CERN exhibition, Austria’s scientific community has organised a series of events for the general public which have had marked success. The exhibition's next destination will be Portugal and preparations are already underway to ensure that it is another resounding success   The travelling exhibition was designed in collaboration with the University of Geneva, as part of the celebrations for its 450th anniversary, and has already notched up a good number of kilometres as it travels from country to country. “In 2010 the exhibition already had around 55,000 visitors,” explains Rolf Landua, who heads the Education Group. Since its inauguration ...

  11. “Accelerating Science” exhibition zooms to Turkey

    CERN Multimedia

    Joannah Caborn Wengler

    2012-01-01

    'Accelerating Science', CERN’s travelling science outreach exhibition, has just arrived at the Middle East Technical University (METU) in Ankara, Turkey for a four-month stay there. This is the first time it has moved outside the circle of the Member States. The Turkish venue will inaugurate some new exhibits that have recently been developed by CERN’s software developers.   “It’s been a very busy day,” says Bilge Demirkoz, an associate professor of physics at METU and a member of AMS-02, who had been overseeing the unloading of the lorries when we spoke to her. “As the University doesn’t have a specific exhibition space, the CERN exhibits are going to be housed in the covered tennis courts just behind the cultural and congress centre. It’s a beautiful venue, and there are plenty of parking spaces.” The University has sent invitations to the exhibition to high schools and to about 100 ...

  12. Dual Function Additives: A Small Molecule Crosslinker for Enhanced Efficiency and Stability in Organic Solar Cells

    KAUST Repository

    Rumer, Joseph W.; Ashraf, Raja S.; Eisenmenger, Nancy D.; Huang, Zhenggang; Meager, Iain; Nielsen, Christian B.; Schroeder, Bob C.; Chabinyc, Michael L.; McCulloch, Iain

    2015-01-01

    A bis-azide-based small molecule crosslinker is synthesized and evaluated as both a stabilizing and efficiency-boosting additive in bulk heterojunction organic photovoltaic cells. Activated by a noninvasive and scalable solution processing technique, polymer:fullerene blends exhibit improved thermal stability with suppressed polymer skin formation at the cathode and frustrated fullerene aggregation on ageing, with initial efficiency increased from 6% to 7%. © 2015 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. Dual Function Additives: A Small Molecule Crosslinker for Enhanced Efficiency and Stability in Organic Solar Cells

    KAUST Repository

    Rumer, Joseph W.

    2015-02-01

    A bis-azide-based small molecule crosslinker is synthesized and evaluated as both a stabilizing and efficiency-boosting additive in bulk heterojunction organic photovoltaic cells. Activated by a noninvasive and scalable solution processing technique, polymer:fullerene blends exhibit improved thermal stability with suppressed polymer skin formation at the cathode and frustrated fullerene aggregation on ageing, with initial efficiency increased from 6% to 7%. © 2015 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. Influence of particle size and preparation methods on the physical and chemical stability of amorphous simvastatin

    DEFF Research Database (Denmark)

    Zhang, Fang; Aaltonen, Jaakko; Tian, Fang

    2009-01-01

    This study investigated the factors influencing the stability of amorphous simvastatin. Quench-cooled amorphous simvastatin in two particle size ranges, 150-180 microm (QC-big) and ... compared to the crystalline form. The rank of solubility was found to be QC-big=QC-small>CM>crystalline. For the physical stability, the highest crystallization rate was observed for CM, and the slowest rate was detected for QC-big, with an intermediate rate occurring for QC-small. QC exhibited lower...

  15. Errors on interrupter tasks presented during spatial and verbal working memory performance are linearly linked to large-scale functional network connectivity in high temporal resolution resting state fMRI.

    Science.gov (United States)

    Magnuson, Matthew Evan; Thompson, Garth John; Schwarb, Hillary; Pan, Wen-Ju; McKinley, Andy; Schumacher, Eric H; Keilholz, Shella Dawn

    2015-12-01

    The brain is organized into networks composed of spatially separated anatomical regions exhibiting coherent functional activity over time. Two of these networks (the default mode network, DMN, and the task positive network, TPN) have been implicated in the performance of a number of cognitive tasks. To directly examine the stable relationship between network connectivity and behavioral performance, high temporal resolution functional magnetic resonance imaging (fMRI) data were collected during the resting state, and behavioral data were collected from 15 subjects on different days, exploring verbal working memory, spatial working memory, and fluid intelligence. Sustained attention performance was also evaluated in a task interleaved between resting state scans. Functional connectivity within and between the DMN and TPN was related to performance on these tasks. Decreased TPN resting state connectivity was found to significantly correlate with fewer errors on an interrupter task presented during a spatial working memory paradigm and decreased DMN/TPN anti-correlation was significantly correlated with fewer errors on an interrupter task presented during a verbal working memory paradigm. A trend for increased DMN resting state connectivity to correlate to measures of fluid intelligence was also observed. These results provide additional evidence of the relationship between resting state networks and behavioral performance, and show that such results can be observed with high temporal resolution fMRI. Because cognitive scores and functional connectivity were collected on nonconsecutive days, these results highlight the stability of functional connectivity/cognitive performance coupling.

  16. High-Spatial-Resolution OH PLIF Visualization in a Cavity-Stabilized Ethylene-Air Turbulent Flame

    Science.gov (United States)

    Geipel, Clayton M.; Rockwell, Robert D.; Chelliah, Harsha K.; Cutler, Andrew D.; Spelker, Christopher A.; Hashem, Zeid; Danehy, Paul M.

    2017-01-01

    High-spatial-resolution OH planar laser-induced fluorescence was measured for a premixed ethylene-air turbulent flame in an electrically-heated Mach 2 continuous-flow facility (University of Virginia Supersonic Combustion Facility, Configuration E.) The facility comprised a Mach 2 nozzle, an isolator with flush-wall fuel injectors, a combustor with optical access, and an extender. The flame was anchored at a cavity flameholder with a backward-facing step of height 9 mm. The temperature-insensitive Q1(8) transition of OH was excited using laser light of wavelength 283.55 nm. A spatial filter was used to create a laser sheet approximately 25 microns thick based on full-width at half maximum (FWHM). Extension tubes increased the magnification of an intensified camera system, achieving in-plane resolution of 40 microns based on a 50% modulation transfer function (MTF). The facility was tested with total temperature 1200 K, total pressure 300 kPa, local fuel/air equivalence ratios of approximately 0.4, and local Mach number of approximately 0.73 in the combustor. A test case with reduced total temperature and another with reduced equivalence ratio were also tested. PLIF images were acquired along a streamwise plane bisecting the cavity flameholder, from the backward facing step to 120 mm downstream of the step. The smallest observed features in the flow had width of approximately 110 microns. Flame surface density was calculated for OH PLIF images.

  17. Development and applications of coherent imaging with improved temporal and spatial resolution

    International Nuclear Information System (INIS)

    Mokso, Rajmund

    2006-01-01

    This work has 2 purposes: the improvement of both temporal and spatial resolution of X-ray tomography. The first part is devoted to the technical aspects of the tomographic technique, particularly at the ESRF (European Synchrotron Radiation Facility) beamline ID19, and the application of the new acquisition scheme to the imaging of liquid foams. We have improved the temporal resolution and field of view of the setup, which allowed to obtain for the first time experimental data with good statistics on three dimensional liquid foams. In the second part of the thesis we have described the Kirkpatrick-Baez focusing system and its first applications. In terms of stability and image quality the developments presented in this part of the thesis provide valuable evidence for the feasibility of phase contrast tomography in magnifying geometry. Since the ultimate goal of this research is to improve the spatial resolution in tomography for applications, four different contributions are important for the characterization of the imaging system: 1) the thermal stability and mechanical imperfections, 2) effects of distortion induced by mirror imperfections, 3) effects of refraction on sample borders, and 4) phase propagation effects with the influence of the magnification. Each of these factors has been studied

  18. Plutonium inventories for stabilization and stabilized materials

    Energy Technology Data Exchange (ETDEWEB)

    Williams, A.K.

    1996-05-01

    The objective of the breakout session was to identify characteristics of materials containing plutonium, the need to stabilize these materials for storage, and plans to accomplish the stabilization activities. All current stabilization activities are driven by the Defense Nuclear Facilities Safety Board Recommendation 94-1 (May 26, 1994) and by the recently completed Plutonium ES&H Vulnerability Assessment (DOE-EH-0415). The Implementation Plan for accomplishing stabilization of plutonium-bearing residues in response to the Recommendation and the Assessment was published by DOE on February 28, 1995. This Implementation Plan (IP) commits to stabilizing problem materials within 3 years, and stabilizing all other materials within 8 years. The IP identifies approximately 20 metric tons of plutonium requiring stabilization and/or repackaging. A further breakdown shows this material to consist of 8.5 metric tons of plutonium metal and alloys, 5.5 metric tons of plutonium as oxide, and 6 metric tons of plutonium as residues. Stabilization of the metal and oxide categories containing greater than 50 weight percent plutonium is covered by DOE Standard {open_quotes}Criteria for Safe Storage of Plutonium Metals and Oxides{close_quotes} December, 1994 (DOE-STD-3013-94). This standard establishes criteria for safe storage of stabilized plutonium metals and oxides for up to 50 years. Each of the DOE sites and contractors with large plutonium inventories has either started or is preparing to start stabilization activities to meet these criteria.

  19. Sex, estradiol, and spatial memory in a food-caching corvid.

    Science.gov (United States)

    Rensel, Michelle A; Ellis, Jesse M S; Harvey, Brigit; Schlinger, Barney A

    2015-09-01

    Estrogens significantly impact spatial memory function in mammalian species. Songbirds express the estrogen synthetic enzyme aromatase at relatively high levels in the hippocampus and there is evidence from zebra finches that estrogens facilitate performance on spatial learning and/or memory tasks. It is unknown, however, whether estrogens influence hippocampal function in songbirds that naturally exhibit memory-intensive behaviors, such as cache recovery observed in many corvid species. To address this question, we examined the impact of estradiol on spatial memory in non-breeding Western scrub-jays, a species that routinely participates in food caching and retrieval in nature and in captivity. We also asked if there were sex differences in performance or responses to estradiol. Utilizing a combination of an aromatase inhibitor, fadrozole, with estradiol implants, we found that while overall cache recovery rates were unaffected by estradiol, several other indices of spatial memory, including searching efficiency and efficiency to retrieve the first item, were impaired in the presence of estradiol. In addition, males and females differed in some performance measures, although these differences appeared to be a consequence of the nature of the task as neither sex consistently out-performed the other. Overall, our data suggest that a sustained estradiol elevation in a food-caching bird impairs some, but not all, aspects of spatial memory on an innate behavioral task, at times in a sex-specific manner. Copyright © 2015 Elsevier Inc. All rights reserved.

  20. On stability and monotonicity requirements of finite difference approximations of stochastic conservation laws with random viscosity

    KAUST Repository

    Pettersson, Per

    2013-05-01

    The stochastic Galerkin and collocation methods are used to solve an advection-diffusion equation with uncertain and spatially varying viscosity. We investigate well-posedness, monotonicity and stability for the extended system resulting from the Galerkin projection of the advection-diffusion equation onto the stochastic basis functions. High-order summation-by-parts operators and weak imposition of boundary conditions are used to prove stability of the semi-discrete system.It is essential that the eigenvalues of the resulting viscosity matrix of the stochastic Galerkin system are positive and we investigate conditions for this to hold. When the viscosity matrix is diagonalizable, stochastic Galerkin and stochastic collocation are similar in terms of computational cost, and for some cases the accuracy is higher for stochastic Galerkin provided that monotonicity requirements are met. We also investigate the total spatial operator of the semi-discretized system and its impact on the convergence to steady-state. © 2013 Elsevier B.V.

  1. On stability and monotonicity requirements of finite difference approximations of stochastic conservation laws with random viscosity

    KAUST Repository

    Pettersson, Per; Doostan, Alireza; Nordströ m, Jan

    2013-01-01

    The stochastic Galerkin and collocation methods are used to solve an advection-diffusion equation with uncertain and spatially varying viscosity. We investigate well-posedness, monotonicity and stability for the extended system resulting from the Galerkin projection of the advection-diffusion equation onto the stochastic basis functions. High-order summation-by-parts operators and weak imposition of boundary conditions are used to prove stability of the semi-discrete system.It is essential that the eigenvalues of the resulting viscosity matrix of the stochastic Galerkin system are positive and we investigate conditions for this to hold. When the viscosity matrix is diagonalizable, stochastic Galerkin and stochastic collocation are similar in terms of computational cost, and for some cases the accuracy is higher for stochastic Galerkin provided that monotonicity requirements are met. We also investigate the total spatial operator of the semi-discretized system and its impact on the convergence to steady-state. © 2013 Elsevier B.V.

  2. Thermal stability of Dion-Jacobson mixed-metal-niobate double-layered perovskites

    International Nuclear Information System (INIS)

    Hermann, Andrew T.; Wiley, John B.

    2009-01-01

    The thermal stability and decomposition pathways of six Dion-Jacobson-related double-layered perovskites, ALaNb 2 O 7 (A = H, Li, Na, Ag) and (ACl)LaNb 2 O 7 (A = Fe, Cu), are investigated. These compounds are made by low temperature ( 2 O 7 . All the compounds are low temperature phases with some of them exhibiting decomposition exotherms consistent with metastability. Decomposition temperatures and reactions pathways vary with the identity of A with most decompositions resulting in the formation of a niobate (containing A) and LaNbO 4 . Results from differential scanning calorimetry and high temperature X-ray powder diffraction studies are presented and structural parameters pertinent to compound stability discussed

  3. Dynamics and Stability of Permanent-Magnet Synchronous Motor

    Directory of Open Access Journals (Sweden)

    Ren He

    2017-01-01

    Full Text Available The aim of this article is to explore the dynamic characteristics and stability of the permanent-magnet synchronous motor (PMSM. PMSM equilibrium local stability condition and Hopf  bifurcation condition, pitchfork bifurcation condition, and fold bifurcation condition have been derived by using the Routh-Hurwitz criterion and the bifurcation theory, respectively. Bifurcation curves of the equilibrium with single and double parameters are obtained by continuation method. Numerical simulations not only confirm the theoretical analysis results but also show one kind of codimension-two-bifurcation points of the equilibrium. PMSM, with or without external load, can exhibit rich dynamic behaviors in different parameters regions. It is shown that if unstable equilibrium appears in the parameters regions, the PMSM may not be able to work stably. To ensure the PMSMs work stably, the inherent parameters should be designed in the region which has only one stable equilibrium.

  4. Facile fabrication of a superhydrophobic fabric with mechanical stability and easy-repairability.

    Science.gov (United States)

    Zhu, Xiaotao; Zhang, Zhaozhu; Yang, Jin; Xu, Xianghui; Men, Xuehu; Zhou, Xiaoyan

    2012-08-15

    The poor mechanical stability of superhydrophobic fabrics severely hindered their use in practical applications. Herein, to address this problem, we fabricated a superhydrophobic fabric with both mechanical stability and easy-repairability by a simple method. The mechanical durability of the obtained superhydrophobic fabric was evaluated by finger touching and abrasion with sandpaper. The results show that rough surface textures of the fabric were retained, and the fabric surface still exhibited superhydrophobicity after tests. More importantly, when the fabric lost its superhydrophobicity after a long-time abrasion, it can be easily rendered with superhydrophobicity once more by a regeneration process. Copyright © 2012 Elsevier Inc. All rights reserved.

  5. Graphene oxide stabilized by PLA-PEG copolymers for the controlled delivery of paclitaxel.

    Science.gov (United States)

    Angelopoulou, A; Voulgari, E; Diamanti, E K; Gournis, D; Avgoustakis, K

    2015-06-01

    To investigate the application of water-dispersible poly(lactide)-poly(ethylene glycol) (PLA-PEG) copolymers for the stabilization of graphene oxide (GO) aqueous dispersions and the feasibility of using the PLA-PEG stabilized GO as a delivery system for the potent anticancer agent paclitaxel. A modified Staudenmaier method was applied to synthesize graphene oxide (GO). Diblock PLA-PEG copolymers were synthesized by ring-opening polymerization of dl-lactide in the presence of monomethoxy-poly(ethylene glycol) (mPEG). Probe sonication in the presence of PLA-PEG copolymers was applied in order to reduce the hydrodynamic diameter of GO to the nano-size range according to dynamic light scattering (DLS) and obtain nano-graphene oxide (NGO) composites with PLA-PEG. The composites were characterized by atomic force microscopy (AFM), thermogravimetric analysis (TGA), and DLS. The colloidal stability of the composites was evaluated by recording the size of the composite particles with time and the resistance of composites to aggregation induced by increasing concentrations of NaCl. The composites were loaded with paclitaxel and the in vitro release profile was determined. The cytotoxicity of composites against A549 human lung cancer cells in culture was evaluated by flow cytometry. The uptake of FITC-labeled NGO/PLA-PEG by A549 cells was also estimated with flow cytometry and visualized with fluorescence microscopy. The average hydrodynamic diameter of NGO/PLA-PEG according to DLS ranged between 455 and 534 nm, depending on the molecular weight and proportion of PLA-PEG in the composites. NGO/PLA-PEG exhibited high colloidal stability on storage and in the presence of high concentrations of NaCl (far exceeding physiological concentrations). Paclitaxel was effectively loaded in the composites and released by a highly sustained fashion. Drug release could be regulated by the molecular weight of the PLA-PEG copolymer and its proportion in the composite. The paclitaxel

  6. "Big Science" exhibition at Balexert

    CERN Multimedia

    2008-01-01

    CERN is going out to meet those members of the general public who were unable to attend the recent Open Day. The Laboratory will be taking its "Big Science" exhibition from the Globe of Science and Innovation to the Balexert shopping centre from 19 to 31 May 2008. The exhibition, which shows the LHC and its experiments through the eyes of a photographer, features around thirty spectacular photographs measuring 4.5 metres high and 2.5 metres wide. Welcomed and guided around the exhibition by CERN volunteers, shoppers at Balexert will also have the opportunity to discover LHC components on display and watch films. "Fun with Physics" workshops will be held at certain times of the day. Main hall of the Balexert shopping centre, ground floor, from 9.00 a.m. to 7.00 p.m. Monday to Friday and from 10 a.m. to 6 p.m. on the two Saturdays. Call for volunteers All members of the CERN personnel are invited to enrol as volunteers to help welcom...

  7. Rational Design of Thermally Stable Novel Biocatalytic Nanomaterials: Enzyme Stability in Restricted Spatial Dimensions

    Science.gov (United States)

    Mudhivarthi, Vamsi K.

    Enzyme stability is of intense interest in bio-materials science as biocatalysts, and as sensing platforms. This is essentially because the unique properties of DNA, RNA, PAA can be coupled with the interesting and novel properties of proteins to produce systems with unprecedented control over their properties. In this article, the very first examples of enzyme/NA/inorganic hybrid nanomaterials and enzyme-Polyacrylic acid conjugates will be presented. The basic principles of design, synthesis and control of properties of these hybrid materials will be presented first, and this will be followed by a discussion of selected examples from our recent research findings. Data show that key properties of biological catalysts are improved by the inorganic framework especially when the catalyst is co-embedded with DNA. Several examples of such studies with various enzymes and proteins, including horseradish peroxidase (HRP), glucose oxidase (GO), cytochrome c (Cyt c), met-hemoglobin (Hb) and met-myoglobin (Mb) will be discussed. Additionally, key insights obtained by the standard methods of materials science including XRD, SEM and TEM as well as biochemical, calorimetric and spectroscopic methods will be discussed. Furthermore, improved structure and enhanced activities of the biocatalysts in specific cases will be demonstrated along with the potential stabilization mechanisms. Our hypothesis is that nucleic acids provide an excellent control over the enzyme-solid interactions as well as rational assembly of nanomaterials. These novel nanobiohybrid materials may aid in engineering more effective synthetic materials for gene-delivery, RNA-delivery and drug delivery applications.

  8. Methods of stabilizing a permanent maglev rotator in heart pumps and other rotary machines

    Directory of Open Access Journals (Sweden)

    kun-xi qian

    2014-10-01

    Full Text Available Permanent maglev rotator in a rotary machine could be stabilized according to the author’s experiences, by use of a non-PM (permanent magnetic force acting together with the PM force, and a non-PM bearing functioning together with the PM bearing, or a so-called gyro-effect which can stabilize all rotators including permanent maglev rotator. This paper presents both axially and radially driven permanent maglev centrifugal heart pumps, as well as a permanent maglev turbine machine and an industrially used permanent maglev centrifugal pump. In all this devices permanent maglev rotators achieve stable equilibrium by different approaches described in detail. Finally, the principle exhibition of gyro-effect and the route chart to stabilization of permanent maglev rotator are presented.

  9. Uniform functional structure across spatial scales in an intertidal benthic assemblage.

    Science.gov (United States)

    Barnes, R S K; Hamylton, Sarah

    2015-05-01

    To investigate the causes of the remarkable similarity of emergent assemblage properties that has been demonstrated across disparate intertidal seagrass sites and assemblages, this study examined whether their emergent functional-group metrics are scale related by testing the null hypothesis that functional diversity and the suite of dominant functional groups in seagrass-associated macrofauna are robust structural features of such assemblages and do not vary spatially across nested scales within a 0.4 ha area. This was carried out via a lattice of 64 spatially referenced stations. Although densities of individual components were patchily dispersed across the locality, rank orders of importance of the 14 functional groups present, their overall functional diversity and evenness, and the proportions of the total individuals contained within each showed, in contrast, statistically significant spatial uniformity, even at areal scales functional groups in their geospatial context also revealed weaker than expected levels of spatial autocorrelation, and then only at the smaller scales and amongst the most dominant groups, and only a small number of negative correlations occurred between the proportional importances of the individual groups. In effect, such patterning was a surface veneer overlying remarkable stability of assemblage functional composition across all spatial scales. Although assemblage species composition is known to be homogeneous in some soft-sediment marine systems over equivalent scales, this combination of patchy individual components yet basically constant functional-group structure seems as yet unreported. Copyright © 2015 Elsevier Ltd. All rights reserved.

  10. Balancing activity, stability and conductivity of nanoporous core-shell iridium/iridium oxide oxygen evolution catalysts

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Yong-Tae; Lopes, Pietro Papa; Park, Shin-Ae; Lee, A-Yeong; Lim, Jinkyu; Lee, Hyunjoo; Back, Seoin; Jung, Yousung; Danilovic, Nemanja; Stamenkovic, Vojislav; Erlebacher, Jonah; Snyder, Joshua; Markovic, Nenad M.

    2017-11-13

    The selection of oxide materials for catalyzing the Oxygen Evolution Reaction in acid-based electrolyzers must be guided by the proper balance between activity, stability and conductivity – a challenging mission of great importance for delivering affordable and environmentally friendly hydrogen. Here we report that the highly conductive nanoporous architecture of an iridium oxide shell on a metallic iridium core, formed through the fast dealloying of osmium from an Ir25Os75 alloy, exhibits an exceptional balance between oxygen evolution activity and stability as quantified by the Activity-Stability FactorASF. Based on this metric, the nanoporous Ir/IrO2 morphology of dealloyed Ir25Os75 shows a factor of ~30 improvement ASFrelative to conventional Ir-based oxide materials and a ~8 times improvement over dealloyed Ir25Os75 nanoparticles due to optimized stability and conductivity, respectively. We propose that the Activity-Stability FactorASF is the key “metric” for determining the technological relevance of oxide-based anodic water electrolyzer catalysts.

  11. Stabilization of Phenylalanine Ammonia Lyase from Rhodotorula glutinis by Encapsulation in Polyethyleneimine-Mediated Biomimetic Silica.

    Science.gov (United States)

    Cui, Jiandong; Liang, Longhao; Han, Cong; Lin Liu, Rong

    2015-06-01

    Phenylalanine ammonia lyase (PAL) from Rhodotorula glutinis was encapsulated within polyethyleneimine-mediated biomimetic silica. The main factors in the preparation of biomimetic silica were optimized by response surface methodology (RSM). Compared to free PAL (about 2 U), the encapsulated PAL retained more than 43 % of their initial activity after 1 h of incubation time at 60 °C, whereas free PAL lost most of activity in the same conditions. It was clearly indicated that the thermal stability of PAL was improved by encapsulation. Moreover, the encapsulated PAL exhibited the excellent stability of the enzyme against denaturants and storage stability, and pH stability was improved by encapsulation. Operational stability of 7 reaction cycles showed that the encapsulated PAL was stable. Nevertheless, the K m value of encapsulated PAL in biomimetic silica was higher than that of the free PAL due to lower total surface area and increased mass transfer resistance.

  12. How Spatial Relationships Influence Economic Preferences for Wind Power—A Review

    Directory of Open Access Journals (Sweden)

    Lauren Knapp

    2015-06-01

    Full Text Available An increasing number of studies in the environmental and resource economic literature suggest that preferences for changes or improvements in environmental amenities, from water quality to recreation, are spatially heterogeneous. One of these effects in particular, distance decay, suggests that respondents exhibit a higher willingness to pay (WTP the closer they live to a proposed environmental improvement and vice versa. The importance of spatial effects cannot be underestimated. Several of these studies find significant biases in aggregate WTP values, and therefore social welfare, from models that disregard spatial factors. This relationship between spatial aspects and preferences, however, remains largely ignored in the non-market valuation literature applied to valuing preferences for renewable energy, generally, and wind power, specifically. To our knowledge, fourteen peer-reviewed studies have been conducted to estimate stated preferences (SP for onshore and/or offshore wind development, yet less than half of those utilize any measure to account for the relationship between spatial effects and preferences. Fewer still undertake more robust measures that account for these spatially dependent relationships, such as via GIS, outside incorporating a single ‘distance’ attribute within the choice experiment (CE referenda. This paper first reviews the methodologies of the SP wind valuation studies that have integrated measure(s to account for spatial effects. We then categorize these effects into three dimensions—distance to a proposed wind project, distance to existing wind project(s, and cumulative effects—supporting each with a discussion of significant findings, including those found in the wind hedonic and acceptance literature. Policy implications that can be leveraged to maximize social welfare when siting future wind projects as well as recommendations for additional research to control for preference spatial heterogeneity in wind

  13. Novel carboxymethyl cellulose-polyvinyl alcohol blend films stabilized by Pickering emulsion incorporation method.

    Science.gov (United States)

    Fasihi, Hadi; Fazilati, Mohammad; Hashemi, Mahdi; Noshirvani, Nooshin

    2017-07-01

    The aim of this study was to investigate the possibility of increasing the antimicrobial and antioxidant properties of biodegradable active films stabilized via Pickering emulsions. The blend films were prepared from carboxymethyl cellulose (CMC) and polyvinyl alcohol (PVA), emulsified with oleic acid (OL) and incorporated with rosemary essential oil (REO). Formation of Pickering emulsion was confirmed by scanning electron microscopy (SEM), optical microscopy, mean droplet size and emulsion stability. Morphological, optical, physical, mechanical, thermal, antifungal and antioxidant properties of the films incorporated with different concentrations of REO (0.5, 1.5 and 3%) were determined. The results showed an increase in UV absorbance and elongation at break but, a decrease in tensile strength and thermal stability of the films. Interestingly, films containing REO exhibited considerable antioxidant and antimicrobial properties. In vitro microbial tests exhibited 100% fungal inhibition against Penicillium digitatum in the films containing 3% REO. In addition, no fungal growth were observed after 60days of storage at 25°C in bread slices were stored with active films incorporated with 3% REO, could attributed to the slow and regular release of REO caused by Pickering emulsions. The results of this study suggest that Pickering emulsion is a very promising method, which significantly affects antioxidant and antimicrobial activities of the films. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. Hierarchical spatial structure of stream fish colonization and extinction

    Science.gov (United States)

    Hitt, N.P.; Roberts, J.H.

    2012-01-01

    Spatial variation in extinction and colonization is expected to influence community composition over time. In stream fish communities, local species richness (alpha diversity) and species turnover (beta diversity) are thought to be regulated by high extinction rates in headwater streams and high colonization rates in downstream areas. We evaluated the spatiotemporal structure of fish communities in streams originally surveyed by Burton and Odum 1945 (Ecology 26: 182-194) in Virginia, USA and explored the effects of species traits on extinction and colonization dynamics. We documented dramatic changes in fish community structure at both the site and stream scales. Of the 34 fish species observed, 20 (59%) were present in both time periods, but 11 (32%) colonized the study area and three (9%) were extirpated over time. Within streams, alpha diversity increased in two of three streams but beta diversity decreased dramatically in all streams due to fish community homogenization caused by colonization of common species and extirpation of rare species. Among streams, however, fish communities differentiated over time. Regression trees indicated that reproductive life-history traits such as spawning mound construction, associations with mound-building species, and high fecundity were important predictors of species persistence or colonization. Conversely, native fishes not associated with mound-building exhibited the highest rates of extirpation from streams. Our results demonstrate that stream fish colonization and extinction dynamics exhibit hierarchical spatial structure and suggest that mound-building fishes serve as keystone species for colonization of headwater streams.

  15. Children's Spatial Thinking: Does Talk about the Spatial World Matter?

    Science.gov (United States)

    Pruden, Shannon M.; Levine, Susan C.; Huttenlocher, Janellen

    2011-01-01

    In this paper we examine the relations between parent spatial language input, children's own production of spatial language, and children's later spatial abilities. Using a longitudinal study design, we coded the use of spatial language (i.e. words describing the spatial features and properties of objects; e.g. big, tall, circle, curvy, edge) from…

  16. Line and word bisection in right-brain-damaged patients with left spatial neglect.

    Science.gov (United States)

    Veronelli, Laura; Vallar, Giuseppe; Marinelli, Chiara V; Primativo, Silvia; Arduino, Lisa S

    2014-01-01

    Right-brain-damaged patients with left unilateral spatial neglect typically set the mid-point of horizontal lines to the right of the objective center. By contrast, healthy participants exhibit a reversed bias (pseudoneglect). The same effect has been described also when bisecting orthographic strings. In particular, for this latter kind of stimulus, some recent studies have shown that visuo-perceptual characteristics, like stimulus length, may contribute to both the magnitude and the direction bias of the bisection performance (Arduino et al. in Neuropsychologia 48:2140-2146, 2010). Furthermore, word stress was shown to modulate reading performances in both healthy participants, and patients with left spatial neglect and neglect dyslexia (Cubelli and Beschin in Brain Lang 95:319-326, 2005; Rusconi et al. in Neuropsychology 18:135-140, 2004). In Experiment I, 22 right-brain-damaged patients (11 with left visuo-spatial neglect) and 11 matched neurologically unimpaired control participants were asked to set the subjective mid-point of word letter strings, and of lines of comparable length. Most patients exhibited an overall disproportionate rightward bias, sensitive to stimulus length, and similar for words and lines. Importantly, in individual patients, biases differed according to stimulus type (words vs. lines), indicating that at least partly different mechanisms may be involved. In Experiment II, the putative effects on the bisection bias of ortho-phonological information (i.e., word stress endings), arising from the non-neglected right hand side of the stimulus were investigated. The orthographic cue induced a rightward shift of the perceived mid-point in both patients and controls, with short words stressed on the antepenultimate final sequence inducing a smaller rightward deviation with respect to short words stressed on the penultimate final sequence. In conclusion, partly different mechanisms, including both visuo-spatial and lexical factors, may support

  17. Shaping the spatial and spectral emissivity at the diffraction limit

    International Nuclear Information System (INIS)

    Makhsiyan, Mathilde; Bouchon, Patrick; Jaeck, Julien; Pelouard, Jean-Luc; Haïdar, Riad

    2015-01-01

    Metasurfaces have attracted a growing interest for their ability to artificially tailor an electromagnetic response on various spectral ranges. In particular, thermal sources with unprecedented abilities, such as directionality or monochromaticity, have been achieved. However, these metasurfaces exhibit homogeneous optical properties whereas the spatial modulation of the emissivity up to the wavelength scale is at the crux of the design of original emitters. In this letter, we study an inhomogeneous metasurface made of a nonperiodic set of optical nano-antennas that spatially and spectrally control the emitted light up to the diffraction limit. Each antenna acts as an independent deep subwavelength emitter for given polarization and wavelength. Their juxtaposition at the subwavelength scale encodes far field multispectral and polarized images. This opens up promising breakthroughs for applications such as optical storage, anti-counterfeit devices, and multispectral emitters for biochemical sensing

  18. Shaping the spatial and spectral emissivity at the diffraction limit

    Energy Technology Data Exchange (ETDEWEB)

    Makhsiyan, Mathilde [MiNaO, ONERA, The French Aerospace Lab, 91761 Palaiseau (France); MiNaO, Laboratoire de Photonique et de Nanostructures (LPN), CNRS, Université Paris-Saclay, route de Nozay, F-91460 Marcoussis (France); Bouchon, Patrick, E-mail: patrick.bouchon@onera.fr; Jaeck, Julien [MiNaO, ONERA, The French Aerospace Lab, 91761 Palaiseau (France); Pelouard, Jean-Luc [MiNaO, Laboratoire de Photonique et de Nanostructures (LPN), CNRS, Université Paris-Saclay, route de Nozay, F-91460 Marcoussis (France); Haïdar, Riad [MiNaO, ONERA, The French Aerospace Lab, 91761 Palaiseau (France); École Polytechnique, Département de Physique, 91128 Palaiseau (France)

    2015-12-21

    Metasurfaces have attracted a growing interest for their ability to artificially tailor an electromagnetic response on various spectral ranges. In particular, thermal sources with unprecedented abilities, such as directionality or monochromaticity, have been achieved. However, these metasurfaces exhibit homogeneous optical properties whereas the spatial modulation of the emissivity up to the wavelength scale is at the crux of the design of original emitters. In this letter, we study an inhomogeneous metasurface made of a nonperiodic set of optical nano-antennas that spatially and spectrally control the emitted light up to the diffraction limit. Each antenna acts as an independent deep subwavelength emitter for given polarization and wavelength. Their juxtaposition at the subwavelength scale encodes far field multispectral and polarized images. This opens up promising breakthroughs for applications such as optical storage, anti-counterfeit devices, and multispectral emitters for biochemical sensing.

  19. Stability of nonlinear waves and patterns and related topics

    Science.gov (United States)

    Ghazaryan, Anna; Lafortune, Stephane; Manukian, Vahagn

    2018-04-01

    Periodic and localized travelling waves such as wave trains, pulses, fronts and patterns of more complex structure often occur in natural and experimentally built systems. In mathematics, these objects are realized as solutions of nonlinear partial differential equations. The existence, dynamic properties and bifurcations of those solutions are of interest. In particular, their stability is important for applications, as the waves that are observable are usually stable. When the waves are unstable, further investigation is warranted of the way the instability is exhibited, i.e. the nature of the instability, and also coherent structures that appear as a result of an instability of travelling waves. A variety of analytical, numerical and hybrid techniques are used to study travelling waves and their properties. This article is part of the theme issue `Stability of nonlinear waves and patterns and related topics'.

  20. Stabilizing Effects of Bacterial Biofilms: EPS Penetration and Redistribution of Bed Stability Down the Sediment Profile

    Science.gov (United States)

    Chen, X. D.; Zhang, C. K.; Zhou, Z.; Gong, Z.; Zhou, J. J.; Tao, J. F.; Paterson, D. M.; Feng, Q.

    2017-12-01

    Biofilms, consisting of microorganisms and their secreted extracellular polymeric substances (EPSs), serve as "ecosystem engineers" stabilizing sedimentary environments. Natural sediment bed provides an excellent substratum for biofilm growth. The porous structure and rich nutrients allow the EPS matrix to spread deeper into the bed. A series of laboratory-controlled experiments were conducted to investigate sediment colonization of Bacillus subtilis and the penetration of EPS into the sediment bed with incubation time. In addition to EPS accumulation on the bed surface, EPS also penetrated downward. However, EPS distribution developed strong vertical heterogeneity with a much higher content in the surface layer than in the bottom layer. Scanning electron microscope images of vertical layers also displayed different micromorphological properties of sediment-EPS matrix. In addition, colloidal and bound EPSs exhibited distinctive distribution patterns. After the full incubation, the biosedimentary beds were eroded to test the variation of bed stability induced by biological effects. This research provides an important reference for the prediction of sediment transport and hence deepens the understanding of the biologically mediated sediment system and broadens the scope of the burgeoning research field of "biomorphodynamics."