WorldWideScience

Sample records for evolution driving forces

  1. SINEs as driving forces in genome evolution.

    Science.gov (United States)

    Schmitz, J

    2012-01-01

    SINEs are short interspersed elements derived from cellular RNAs that repetitively retropose via RNA intermediates and integrate more or less randomly back into the genome. SINEs propagate almost entirely vertically within their host cells and, once established in the germline, are passed on from generation to generation. As non-autonomous elements, their reverse transcription (from RNA to cDNA) and genomic integration depends on the activity of the enzymatic machinery of autonomous retrotransposons, such as long interspersed elements (LINEs). SINEs are widely distributed in eukaryotes, but are especially effectively propagated in mammalian species. For example, more than a million Alu-SINE copies populate the human genome (approximately 13% of genomic space), and few master copies of them are still active. In the organisms where they occur, SINEs are a challenge to genomic integrity, but in the long term also can serve as beneficial building blocks for evolution, contributing to phenotypic heterogeneity and modifying gene regulatory networks. They substantially expand the genomic space and introduce structural variation to the genome. SINEs have the potential to mutate genes, to alter gene expression, and to generate new parts of genes. A balanced distribution and controlled activity of such properties is crucial to maintaining the organism's dynamic and thriving evolution. Copyright © 2012 S. Karger AG, Basel.

  2. Autoimmunity as a Driving Force of Cognitive Evolution

    Directory of Open Access Journals (Sweden)

    Serge Nataf

    2017-10-01

    Full Text Available In the last decades, increasingly robust experimental approaches have formally demonstrated that autoimmunity is a physiological process involved in a large range of functions including cognition. On this basis, the recently enunciated “brain superautoantigens” theory proposes that autoimmunity has been a driving force of cognitive evolution. It is notably suggested that the immune and nervous systems have somehow co-evolved and exerted a mutual selection pressure benefiting to both systems. In this two-way process, the evolutionary-determined emergence of neurons expressing specific immunogenic antigens (brain superautoantigens has exerted a selection pressure on immune genes shaping the T-cell repertoire. Such a selection pressure on immune genes has translated into the emergence of a finely tuned autoimmune T-cell repertoire that promotes cognition. In another hand, the evolutionary-determined emergence of brain-autoreactive T-cells has exerted a selection pressure on neural genes coding for brain superautoantigens. Such a selection pressure has translated into the emergence of a neural repertoire (defined here as the whole of neurons, synapses and non-neuronal cells involved in cognitive functions expressing brain superautoantigens. Overall, the brain superautoantigens theory suggests that cognitive evolution might have been primarily driven by internal cues rather than external environmental conditions. Importantly, while providing a unique molecular connection between neural and T-cell repertoires under physiological conditions, brain superautoantigens may also constitute an Achilles heel responsible for the particular susceptibility of Homo sapiens to “neuroimmune co-pathologies” i.e., disorders affecting both neural and T-cell repertoires. These may notably include paraneoplastic syndromes, multiple sclerosis as well as autism, schizophrenia and neurodegenerative diseases. In the context of this theoretical frame, a specific

  3. Solar Radiation as Driving Force In Early Evolution

    Science.gov (United States)

    Rothschild, Lynn J.; Peterson, David L. (Technical Monitor)

    2002-01-01

    Ultraviolet radiation (UVR) has provided an evolutionary challenge to life on Earth in that it is both an agent of mutation and as well as a selective force. Today surface fluxes of UVR vary diurnally, seasonally, etc. Still, the UVR flux was probably substantially higher during the early phases of evolution, suggesting that its role in evolution was even more prominent during this time. In this presentation, the creative role of UVR in evolution is discussed, specifically in connection with the role that UVR may have played in the evolution of early microbial ecosystems. The presentation will include discussions of the direct influence of UVR on such processes as photosynthesis and genetic damage, as well as the indirect influence of UVR as mediated through the production of reactive oxygen species. These biological effects of UVR will be viewed against the backdrop of the physical nature of the early Earth, surely a very different place then than now.

  4. Gravity: one of the driving forces for evolution.

    Science.gov (United States)

    Volkmann, D; Baluska, F

    2006-12-01

    Mechanical load is 10(3) larger for land-living than for water-living organisms. As a consequence, antigravitational material in form of compound materials like lignified cell walls in plants and mineralised bones in animals occurs in land-living organisms preferentially. Besides cellulose, pectic substances of plant cell walls seem to function as antigravitational material in early phases of plant evolution and development. A testable hypothesis including vesicular recycling processes into the tensegrity concept is proposed for both sensing of gravitational force and responding by production of antigravitational material at the cellular level.

  5. Delegation to automaticity: the driving force for cognitive evolution?

    Science.gov (United States)

    Shine, J M; Shine, R

    2014-01-01

    The ability to delegate control over repetitive tasks from higher to lower neural centers may be a fundamental innovation in human cognition. Plausibly, the massive neurocomputational challenges associated with the mastery of balance during the evolution of bipedality in proto-humans provided a strong selective advantage to individuals with brains capable of efficiently transferring tasks in this way. Thus, the shift from quadrupedal to bipedal locomotion may have driven the rapid evolution of distinctive features of human neuronal functioning. We review recent studies of functional neuroanatomy that bear upon this hypothesis, and identify ways to test our ideas.

  6. Driving Forces of Plate Tectonics and Evolution of the Oceanic Lithosphere and Asthenosphere

    Science.gov (United States)

    Forsyth, D. W.

    2017-12-01

    As plate tectonics became established as an excellent kinematic description of the relative motions of different blocks of the Earth's lithosphere, many investigators also began exploring the forces involved in driving the plate motions. Because the plates move at nearly constant velocities over long periods of time and inertial terms are unimportant, driving forces must always be balanced by resisting forces in a way that regulates the velocities. Forsyth and Uyeda (1975) incorporated the balancing of torques on the individual plates to help constrain the relative importance of the driving and resisting forces, as parameterized in a way based on prior model investigations of individual parts of the convecting system. We found that the primary driving force was sinking of subducting lithosphere at trenches, balanced largely by viscous resisting forces in the sub-asthenospheric mantle; that viscous drag beneath the oceanic plates was negligible; and that mid-ocean ridges provided a relatively small push. One of the early questions was whether there was buoyant upwelling on a large scale beneath mid-ocean ridges as part of a whole mantle convection system with subduction of the plates representing the downwelling limb. If so, then it would be likely that the plates were just riding on top of large convection cells. Seismic tomography has demonstrated that, on average, there are no deep roots beneath mid-ocean ridges, so that active, buoyant upwelling from the deep mantle does not exist beneath spreading centers. However, more recent tomographic studies have found asymmetry of the shear velocity structure beneath ridges in some areas, pointing to a smaller scale of active convection in the shallow mantle perhaps induced by melt retention buoyancy or the local effects of ridge/hotspot interaction.

  7. Empirical Validation of a Hypothesis of the Hormetic Selective Forces Driving the Evolution of Longevity Regulation Mechanisms

    Directory of Open Access Journals (Sweden)

    Alejandra Gomez-Perez

    2016-12-01

    Full Text Available Exogenously added lithocholic bile acid and some other bile acids slow down yeast chronological aging by eliciting a hormetic stress response and altering mitochondrial functionality. Unlike animals, yeast cells do not synthesize bile acids. We therefore hypothesized that bile acids released into an ecosystem by animals may act as interspecies chemical signals that generate selective pressure for the evolution of longevity regulation mechanisms in yeast within this ecosystem. To empirically verify our hypothesis, in this study we carried out a 3-step process for the selection of long-lived yeast species by a long-term exposure to exogenous lithocholic bile acid. Such experimental evolution yielded 20 long-lived mutants, 3 of which were capable of sustaining their considerably prolonged chronological lifespans after numerous passages in medium without lithocholic acid. The extended longevity of each of the 3 long-lived yeast species was a dominant polygenic trait caused by mutations in more than two nuclear genes. Each of the 3 mutants displayed considerable alterations to the age-related chronology of mitochondrial respiration and showed enhanced resistance to chronic oxidative, thermal and osmotic stresses. Our findings empirically validate the hypothesis suggesting that hormetic selective forces can drive the evolution of longevity regulation mechanisms within an ecosystem.

  8. Mining spatial information to investigate the evolution of karst rocky desertification and its human driving forces in Changshun, China.

    Science.gov (United States)

    Xu, Erqi; Zhang, Hongqi; Li, Mengxian

    2013-08-01

    The processes of karst rocky desertification (KRD) have been found to cause the most severe environmental degradation in southwestern China. Understanding the driving forces that cause KRD is essential for managing and restoring the areas that it impacts. Studies of the human driving forces of KRD are limited to the county level, a specific administrative unit in China; census data are acquired at this scale, which can lead to scale biases. Changshun County is studied here as a representative area and anthropogenic influences in the county are accounted for by using Euclidean distances for the proximity to roads and settlements. We propose a standard coefficient of human influence (SOI) that standardizes the Euclidean distances for different KRD transformations to compare the effects of human activities in different areas. In Changshun County, the individual influences of roads and settlements share similar characteristics. The SOIs of improved KRD transformation types are almost negative, but the SOIs of deteriorated types are nearly positive except for one form of KRD turning to the extremely severe KRD. The results indicated that the distribution and evolution of the KRD areas from 2000 to 2010 in Changshun were affected positively by human activities (e.g., KRD restoration projects) and also negatively (e.g., by intense and irrational land use). Our results demonstrate that the spatial techniques and SOI used in this study can effectively incorporate information concerning human influences and internal KRD transformations. This provides a suitable approach for studying the relationships between human activities and KRD processes at fine scales. Copyright © 2013 Elsevier B.V. All rights reserved.

  9. 多倍化是杂草起源与演化的驱动力%Polyploidization, one of the driving forces for weed origin and evolution

    Institute of Scientific and Technical Information of China (English)

    李君; 强胜

    2012-01-01

    杂草及外来植物入侵给全球经济发展及生态环境都带来了严重危害,研究其起源与演化将有助于它们的管理与控制.多倍化是植物进化的主要驱动力量,然而多倍化在杂草起源与演化中的作用还停留在种类统计以及零碎的研究案例证据上.本文综述了植物多倍体基因组结构及基因表达的研究进展以及染色体加倍后的生态学效应.多倍化促进了基因组水平与表型水平的进化,影响物种或群体生存竞争能力和繁殖扩展能力,提高物种或群体生态适应性.这一遗传过程可能促使外来种在新的生境中的成功入侵进而转变为杂草,并提出重视开展对杂草及外来入侵植物的多倍化研究的设想.%Weeds and alien invasive plants have caused tremendously ecological and socio-economic damages and loses worldwide, therefore,it is important to study origin and evolution of weeds for their effective management. Polyploidy is believed to be the main driving force of plant evolution, however, its playing the role in weeds origin and evolution is poorly understood. In this paper we review the progresses on the polyploid genome structure and gene expression and the ecological consequences of chromosome doubling. The polyploidy promotes the evolution of genomic and phenotype, affects the species survival competition, reproduction and expansion capability, and improves the ecological adaptability. Polyploidization can drive the successful invasion of invasive alien species and consequently evolution into a weed in new habitats. In addition, it is proposed that the research works on invasive alien plants may focus on polyploidization function in weed evolution and alien plant invasion.

  10. Technology as a driving force

    Energy Technology Data Exchange (ETDEWEB)

    Torvund, T [Norsk Hydro A/S (Norway)

    1994-12-31

    The competitiveness of the Norwegian Continental shelf has been put firmly on the agenda in Norway since the report from a working group set up by the Ministry of Industry and Energy was released in February this year. If there is to be secured a long future for oil and gas activities, a reduction in the time and costs used in the projects of the order of 40-50%, without jeopardizing the high safety and environmental standards achieved in Norway. The paper addresses how technology can be a driving force in achieving these aims. But technology alone cannot do the job. Progress and changes in several other areas are also necessary, and the new scenario also calls for improved relations between all actors in the North Sea, authorities, oil companies, contractors and labour unions. 15 figs.

  11. Technology as a driving force

    International Nuclear Information System (INIS)

    Torvund, T.

    1994-01-01

    The competitiveness of the Norwegian Continental shelf has been put firmly on the agenda in Norway since the report from a working group set up by the Ministry of Industry and Energy was released in February this year. If there is to be secured a long future for oil and gas activities, a reduction in the time and costs used in the projects of the order of 40-50%, without jeopardizing the high safety and environmental standards achieved in Norway. The paper addresses how technology can be a driving force in achieving these aims. But technology alone cannot do the job. Progress and changes in several other areas are also necessary, and the new scenario also calls for improved relations between all actors in the North Sea, authorities, oil companies, contractors and labour unions. 15 figs

  12. Chemical driving force for rafting in superalloys

    CSIR Research Space (South Africa)

    Nabarro, FRN

    1997-08-15

    Full Text Available The author provides a brief overview of the chemical driving forces for rafting in superalloys. Until recently, all theories of the driving force for rafting have considered the compositions of the two phases to be fixed, although accepting...

  13. Contrasting evolution patterns between glacier-fed and non-glacier-fed lakes in the central Tibetan Plateau and driving force analysis

    Science.gov (United States)

    Song, C.; Sheng, Y.

    2015-12-01

    High-altitude lakes in the Tibetan Plateau (TP) showed strong spatio-temporal variability during past decades. The lake dynamics can be associated with several key factors including lake type, supply of glacial meltwater, local climate variations. It is important to differentiate these factors when analyzing the driving force of lakes dynamics. With a focus on lakes over the Tanggula Mountains of the central TP, this study investigates the temporal evolution patterns of lake area and water level of different types: glacier-fed closed lake, non-glacier-fed closed lake and upstream lake (draining into closed lakes). We collected all available Landsat archive data and quantified the inter-annual variability of lake extents. Results show accelerated expansions of both glacier-fed and non-glacier-fed lakes during 1970s-2013, and different temporal patterns of the two types of lakes: the non-glacier-fed lakes displayed a batch-wise growth pattern, with obvious growth in 2002, 2005 and 2011 and slight changes in other years, while glacier-fed lakes showed steady expanding tendency. The contrasting patterns are confirmed by the distinction of lake level change between the two groups derived from satellite altimetry during 2003-2009. The upstream lakes remained largely stable due to natural drainage regulation. The intermittent expansions for non-glacier-fed lakes were found to be related to excessive precipitation events and positive "precipitation-evaporation". In contrast, glacier-fed lake changes showed weak correlations with precipitation variations, which imply a joint contribution from glacial meltwater to water budgets. A simple estimation reveals that the increased water storage for all of examined lakes contributed from precipitation/evaporation (0.31±0.09 Gt/yr) slightly overweighed the glacial meltwater supply (0.26±0.08 Gt/yr).

  14. Reconstruction of driving forces through recurrence plots

    International Nuclear Information System (INIS)

    Tanio, Masaaki; Hirata, Yoshito; Suzuki, Hideyuki

    2009-01-01

    We consider the problem of reconstructing one-dimensional driving forces only from the observations of driven systems. We extend the approach presented in a seminal paper [M.C. Casdagli, Physica D 108 (1997) 12] and propose a method that is robust and has wider applicability. By reinterpreting the work of Thiel et al. [M. Thiel, M.C. Romano, J. Kurths, Phys. Lett. A 330 (2004) 343], we formulate the reconstruction problem as a combinatorial optimization problem and relax conditions by assuming that a driving force is continuous. The method is demonstrated by using a tent map driven by an external force.

  15. Controlling Casimir force via coherent driving field

    Science.gov (United States)

    Ahmad, Rashid; Abbas, Muqaddar; Ahmad, Iftikhar; Qamar, Sajid

    2016-04-01

    A four level atom-field configuration is used to investigate the coherent control of Casimir force between two identical plates made up of chiral atomic media and separated by vacuum of width d. The electromagnetic chirality-induced negative refraction is obtained via atomic coherence. The behavior of Casimir force is investigated using Casimir-Lifshitz formula. It is noticed that Casimir force can be switched from repulsive to attractive and vice versa via coherent control of the driving field. This switching feature provides new possibilities of using the repulsive Casimir force in the development of new emerging technologies, such as, micro-electro-mechanical and nano-electro-mechanical systems, i.e., MEMS and NEMS, respectively.

  16. Driving forces in the Greenlandic urbanization

    DEFF Research Database (Denmark)

    Hendriksen, Kåre

    2014-01-01

    Generally urbanization is recognised as a natural development where the population is mowing into the larger towns driven by e.g. better job opportunities, larger product and service supply and better education and health services, and it is often argued that this is also the driving forces...... support and with limited export oriented value creation. It will be disused how the previous and present urbanization interact with a sustainable development and what is the core prerequisites for sustainable towns and settlements....

  17. Multiregional Input-Output Analysis of Spatial-Temporal Evolution Driving Force for Carbon Emissions Embodied in Interprovincial Trade and Optimization Policies: Case Study of Northeast Industrial District in China.

    Science.gov (United States)

    Cheng, Hao; Dong, Suocheng; Li, Fujia; Yang, Yang; Li, Shantong; Li, Yu

    2018-01-02

    In the counties with rapid economy and carbon emissions (CEs) growth, CEs embodied in interprovincial trade (CEs-PT) significantly impacts the CEs amount and structure and represents a key issue to consider in CEs reduction policies formulation. This study applied EEBT and two-stage SDA model to analyze the characteristics and driving force of spatial-temporal evolution for net CEs-PT outflow in the Northeast Industrial District of China (NID). We found that, during 1997-2007, the net CEs-PT flowed out from NID to 16 south and east provinces, then to 23 provinces all over China, and its amount has increased 216.798Mt (by 211.67% per year). The main driving forces are technology and demand (further decomposed into structure and scale matrix); the contribution are 71.6418 Mt and 145.1562 Mt. Then, we constructed coupling relationship model and took the top three industries with the greatest net CEs-PT outflow (farming, forestry, animal husbandry and fisheries, electricity and heat production and supply, petroleum processing, coking, and nuclear fuel processing) as examples, adjusted the interprovincial trade constructions, scales, and objects, to reduce the CEs-PT with lower costs, greater effect, and more equitability. The achievement could provide reference for formulating CEs reduction policies for similar areas in the world characterized by rapid growth of economy and CEs.

  18. Microorganism and filamentous fungi drive evolution of plant synapses.

    Science.gov (United States)

    Baluška, František; Mancuso, Stefano

    2013-01-01

    In the course of plant evolution, there is an obvious trend toward an increased complexity of plant bodies, as well as an increased sophistication of plant behavior and communication. Phenotypic plasticity of plants is based on the polar auxin transport machinery that is directly linked with plant sensory systems impinging on plant behavior and adaptive responses. Similar to the emergence and evolution of eukaryotic cells, evolution of land plants was also shaped and driven by infective and symbiotic microorganisms. These microorganisms are the driving force behind the evolution of plant synapses and other neuronal aspects of higher plants; this is especially pronounced in the root apices. Plant synapses allow synaptic cell-cell communication and coordination in plants, as well as sensory-motor integration in root apices searching for water and mineral nutrition. These neuronal aspects of higher plants are closely linked with their unique ability to adapt to environmental changes.

  19. An analysis of the daily precipitation variability in the Himalayan orogen using a statistical parameterisation and its potential in driving landscape evolution models with stochastic climatic forcing

    Science.gov (United States)

    Deal, Eric; Braun, Jean

    2015-04-01

    A current challenge in landscape evolution modelling is to integrate realistic precipitation patterns and behaviour into longterm fluvial erosion models. The effect of precipitation on fluvial erosion can be subtle as well as nonlinear, implying that changes in climate (e.g. precipitation magnitude or storminess) may have unexpected outcomes in terms of erosion rates. For example Tucker and Bras (2000) show theoretically that changes in the variability of precipitation (storminess) alone can influence erosion rate across a landscape. To complicate the situation further, topography, ultimately driven by tectonic uplift but shaped by erosion, has a major influence on the distribution and style of precipitation. Therefore, in order to untangle the coupling between climate, erosion and tectonics in an actively uplifting orogen where fluvial erosion is dominant it is important to understand how the 'rain dial' used in a landscape evolution model (LEM) corresponds to real precipitation patterns. One issue with the parameterisation of rainfall for use in an LEM is the difference between the timescales for precipitation (≤ 1 year) and landscape evolution (> 103 years). As a result, precipitation patterns must be upscaled before being integrated into a model. The relevant question then becomes: What is the most appropriate measure of precipitation on a millennial timescale? Previous work (Tucker and Bras, 2000; Lague, 2005) has shown that precipitation can be properly upscaled by taking into account its variable nature, along with its average magnitude. This captures the relative size and frequency of extreme events, ensuring a more accurate characterisation of the integrated effects of precipitation on erosion over long periods of time. In light of this work, we present a statistical parameterisation that accurately models the mean and daily variability of ground based (APHRODITE) and remotely sensed (TRMM) precipitation data in the Himalayan orogen with only a few

  20. The Secret Driving Force Behind Mongolia’s Successful Democracy

    Science.gov (United States)

    2016-03-01

    the nation’s democracy movement its earliest stages. Courtesy of the Democratic Union of Mongolia PRISM 6, no. 1 FROM THE FIELD | 141 The Secret Driving...assistance and trade. Our state budget PRISM 6, no. 1 FROM THE FIELD | 143 THE SECRET DRIVING FORCE BEHIND MONGOLIA’S SUCCESSFUL DEMOCRACY collapsed; we...O yungerel Tsedevdam ba (2006) PRISM 6, no. 1 FROM THE FIELD | 145 THE SECRET DRIVING FORCE BEHIND MONGOLIA’S SUCCESSFUL DEMOCRACY significantly as

  1. Glenohumeral contact force during flat and topspin tennis forehand drives.

    Science.gov (United States)

    Blache, Yoann; Creveaux, Thomas; Dumas, Raphaël; Chèze, Laurence; Rogowski, Isabelle

    2017-03-01

    The primary role of the shoulder joint in tennis forehand drive is at the expense of the loadings undergone by this joint. Nevertheless, few studies investigated glenohumeral (GH) contact forces during forehand drives. The aim of this study was to investigate GH compressive and shearing forces during the flat and topspin forehand drives in advanced tennis players. 3D kinematics of flat and topspin forehand drives of 11 advanced tennis players were recorded. The Delft Shoulder and Elbow musculoskeletal model was implemented to assess the magnitude and orientation of GH contact forces during the forehand drives. The results showed no differences in magnitude and orientation of GH contact forces between the flat and topspin forehand drives. The estimated maximal GH contact force during the forward swing phase was 3573 ± 1383 N, which was on average 1.25 times greater than during the follow-through phase, and 5.8 times greater than during the backswing phase. Regardless the phase of the forehand drive, GH contact forces pointed towards the anterior-superior part of the glenoid therefore standing for shearing forces. Knowledge of GH contact forces during real sport tasks performed at high velocity may improve the understanding of various sport-specific adaptations and causative factors for shoulder problems.

  2. Entropic forces drive contraction of cytoskeletal networks

    Czech Academy of Sciences Publication Activity Database

    Braun, M.; Lánský, Zdeněk; Hilitski, F.; Dogic, Z.; Diez, S.

    2016-01-01

    Roč. 38, č. 5 (2016), s. 474-481 ISSN 0265-9247 R&D Projects: GA ČR(CZ) GA15-17488S; GA MŠk(CZ) ED1.1.00/02.0109 Institutional support: RVO:86652036 Keywords : cytoskeleton * depletion forces * entropic forces Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 4.441, year: 2016

  3. Evolution of wave turbulence under "gusty" forcing.

    Science.gov (United States)

    Annenkov, S Y; Shrira, V I

    2011-09-09

    We consider nonlinear evolution of a random wave field under gusty forcing, fluctuating around a constant mean. Here the classical wave turbulence theory that assumes a proximity to stationarity is not applicable. We show by direct numerical simulation that the self-similarity of wave field evolution survives under fluctuating forcing. The wave field statistical characteristics averaged over fluctuations of forcing evolve as if there were a certain constant "effective wind." The results justify the use of the kinetic equations with forcing averaged over gusts as a good first approximation.

  4. OSHA Laboratory Standard: Driving Force for Laboratory Safety!

    Science.gov (United States)

    Roy, Kenneth R.

    2000-01-01

    Discusses the Occupational Safety and Health Administration's (OSHA's) Laboratory Safety Standards as the major driving force in establishing and maintaining a safe working environment for teachers and students. (Author)

  5. Characterization of New Isolates of Apricot vein clearing-associated virus and of a New Prunus-Infecting Virus: Evidence for Recombination as a Driving Force in Betaflexiviridae Evolution.

    Directory of Open Access Journals (Sweden)

    Armelle Marais

    Full Text Available Double stranded RNAs from Prunus samples gathered from various surveys were analyzed by a deep-sequencing approach. Contig annotations revealed the presence of a potential new viral species in an Azerbaijani almond tree (Prunus amygdalus and its genome sequence was completed. Its genomic organization is similar to that of the recently described Apricot vein clearing associated virus (AVCaV for which two new isolates were also characterized, in a similar fashion, from two Japanese plums (Prunus salicina from a French germplasm collection. The amino acid identity values between the four proteins encoded by the genome of the new virus have identity levels with those of AVCaV which fall clearly outside the species demarcation criteria. The new virus should therefore be considered as a new species for which the name of Caucasus prunus virus (CPrV has been proposed. Phylogenetic relationships and nucleotide comparisons suggested that together with AVCaV, CPrV could define a new genus (proposed name: Prunevirus in the family Betaflexiviridae. A molecular test targeting both members of the new genus was developed, allowing the detection of additional AVCaV isolates, and therefore extending the known geographical distribution and the host range of AVCaV. Moreover, the phylogenetic trees reconstructed with the amino acid sequences of replicase, movement and coat proteins of representative Betaflexiviridae members suggest that Citrus leaf blotch virus (CLBV, type member of the genus Citrivirus may have evolved from a recombination event involving a Prunevirus, further highlighting the importance of recombination as a driving force in Betaflexiviridae evolution. The sequences reported in the present manuscript have been deposited in the GenBank database under accession numbers KM507061-KM504070.

  6. Driving Force Filtering and Driving Mechanism Analysis of Urban Agricultural Development in Weifang County, China

    Directory of Open Access Journals (Sweden)

    SUI Fei-fei

    2016-03-01

    Full Text Available As an agricultural nation, the agricultural landscape is the basic appearance and existence in China, but the common existence often be neglected and contempted. As a new type of design and ideology, the development of urban agricultural landscape will greatly affect the texture and structure of the urban space. According to the urban agricultural production data and the socio-economic data of Weifang County, a set of evaluation index system that could analyze quantitatively the driving force of urban agricultural production changes and the internal drive mechanism was built. The original driving force indicators of economy, society, resources and environment from the time-series were chosen, and then 15 driving forces from the original driving forces by correlation analysis and principal component analysis were selected. The degree of influence was analyzed and the driving forces model by means of partial least squares(PLS was built. The results demonstrated that the factors greatly influenced the increase of urban agricultural output value in Weifang County were per capita net income of rural residents, agricultural machinery total power, effective irrigation area, centralized treatment rate of urban sewage, with the driving exponents 0.2509, 0.1019, 0.1655, 0.1332, respectively. The negative influence factor was the use amount of agricultural plastic film and the driving exponent was-0.2146. The research provides a reference for the development of urban agriculture, as well as a reference for the related study.

  7. The Driving Forces of Subsidiary Absorptive Capacity

    DEFF Research Database (Denmark)

    Schleimer, Stephanie C.; Pedersen, Torben

    2013-01-01

    The study investigates how a multinational corporation (MNC) can promote the absorptive capacity of its subsidiaries. The focus is on what drives the MNC subsidiary's ability to absorb marketing strategies that are initiated by the MNC parent, as well as how the subsidiary enacts on this absorptive...... as a purposeful response to this dual embeddedness. An analysis of marketing strategy absorptions undertaken by 213 subsidiaries reveals that MNCs can assist their subsidiaries to compete in competitive and dynamic focal markets by forming specific organizational mechanisms that are conducive to the development...

  8. Processes and driving forces in changing cultural landscapes across Europe

    DEFF Research Database (Denmark)

    Bürgi, Matthias; Bieling, Claudia; Von Hackwitz, Kim

    2017-01-01

    Context: Cultural landscapes evolve over time. However, the rate and direction of change might not be in line with societal needs and more information on the forces driving these changes are therefore needed. Objectives: Filling the gap between single case studies and meta-analyses, we present...... perceived landscape changes, and remembered driving forces. Land cover and landscape changes were analysed regarding change, conversions and processes. For all case study areas, narratives on mapped land cover change, perceived landscape changes and driving forces were compiled. Results: Despite a very high...... diversity in extent, direction and rates of change, a few dominant processes and widespread factors driving the changes could be identified in the six case study areas, i.e. access and infrastructure, political shifts, labor market, technological innovations, and for the more recent period climate change...

  9. A guide for statewide impaired-driving task forces.

    Science.gov (United States)

    2009-09-01

    The purpose of the guide is to assist State officials and other stakeholders who are interested in establishing an : Impaired-Driving Statewide Task Force or who are exploring ways to improve their current Task Force. The guide : addresses issues suc...

  10. Motive, desire, drive: the discourse of force

    Directory of Open Access Journals (Sweden)

    Alan Blum

    2013-12-01

    Full Text Available A review of the original paper on motive by Blum and McHugh (1971 is used as an occasion to make transparent an approach to social theory as it has developed over the years in their work. This method, in treating motive as an illustration, engages it as an example of the status of the signifier as a symptom of interpretive conflict endemic to any situation of action, always inviting an analysis of the symbolic order and imaginative structure that sustains the distinction as a force in social life. In this paper, motive in particular is unpacked to show how it serves as an indication of fundamental ambiguity with respect to a problem-solving situation, revealing in this case constant perplexity in relation to the enigmatic character of what comes to view on any occasion and the recurrent contestation that is released.

  11. Wall relaxation and the driving forces for cell expansive growth

    Science.gov (United States)

    Cosgrove, D. J.

    1987-01-01

    When water uptake by growing cells is prevented, the turgor pressure and the tensile stress in the cell wall are reduced by continued wall loosening. This process, termed in vivo stress relaxation, provides a new way to study the dynamics of wall loosening and to measure the wall yield threshold and the physiological wall extensibility. Stress relaxation experiments indicate that wall stress supplies the mechanical driving force for wall yielding. Cell expansion also requires water absorption. The driving force for water uptake during growth is created by wall relaxation, which lowers the water potential of the expanding cells. New techniques for measuring this driving force show that it is smaller than believed previously; in elongating stems it is only 0.3 to 0.5 bar. This means that the hydraulic resistance of the water transport pathway is small and that rate of cell expansion is controlled primarily by wall loosening and yielding.

  12. Pattern-formation under acoustic driving forces

    Science.gov (United States)

    Valverde, Jose Manuel

    2015-07-01

    Chemical and metallurgical processes enhanced by high intensity acoustic waves, thermoacoustic engines and refrigerators, fuel rods in nuclear reactors, heat exchanger tubes, offshore and vibrating structures, solar thermal collectors, acoustic levitators, microfluidic devices, cycling, musical acoustics, blood flow through veins/arteries, hearing in the mammalian ear, carbon nanotube loudspeakers, etc. The evolution of a myriad of processes involving the oscillation of viscous fluids in the presence of solid boundaries is up to a certain extent influenced by acoustic streaming. In addition to the sound field, viscous energy dissipation at the fluid-solid boundary causes a time-independent fluid circulation, which can lead to a significant enhancement of heat, mass and momentum transfer at large oscillation amplitudes. A particularly relevant phenomenon that can be notably affected by acoustic streaming is the promotion of sound waves by temperature gradients or viceversa (thermoacoustics), which is at the basis of potentially efficient and environmental friendly engines and refrigerators that have attracted a renewed interest in the last years. In the present manuscript, historical developments and the underlying basic physics behind acoustic streaming and thermoacoustics are reviewed from an unifying perspective.

  13. Sequential reconstruction of driving-forces from nonlinear nonstationary dynamics

    Science.gov (United States)

    Güntürkün, Ulaş

    2010-07-01

    This paper describes a functional analysis-based method for the estimation of driving-forces from nonlinear dynamic systems. The driving-forces account for the perturbation inputs induced by the external environment or the secular variations in the internal variables of the system. The proposed algorithm is applicable to the problems for which there is too little or no prior knowledge to build a rigorous mathematical model of the unknown dynamics. We derive the estimator conditioned on the differentiability of the unknown system’s mapping, and smoothness of the driving-force. The proposed algorithm is an adaptive sequential realization of the blind prediction error method, where the basic idea is to predict the observables, and retrieve the driving-force from the prediction error. Our realization of this idea is embodied by predicting the observables one-step into the future using a bank of echo state networks (ESN) in an online fashion, and then extracting the raw estimates from the prediction error and smoothing these estimates in two adaptive filtering stages. The adaptive nature of the algorithm enables to retrieve both slowly and rapidly varying driving-forces accurately, which are illustrated by simulations. Logistic and Moran-Ricker maps are studied in controlled experiments, exemplifying chaotic state and stochastic measurement models. The algorithm is also applied to the estimation of a driving-force from another nonlinear dynamic system that is stochastic in both state and measurement equations. The results are judged by the posterior Cramer-Rao lower bounds. The method is finally put into test on a real-world application; extracting sun’s magnetic flux from the sunspot time series.

  14. Driving reconnection in sheared magnetic configurations with forced fluctuations

    Science.gov (United States)

    Pongkitiwanichakul, Peera; Makwana, Kirit D.; Ruffolo, David

    2018-02-01

    We investigate reconnection of magnetic field lines in sheared magnetic field configurations due to fluctuations driven by random forcing by means of numerical simulations. The simulations are performed with an incompressible, pseudo-spectral magnetohydrodynamics code in 2D where we take thick, resistively decaying, current-sheet like sheared magnetic configurations which do not reconnect spontaneously. We describe and test the forcing that is introduced in the momentum equation to drive fluctuations. It is found that the forcing does not change the rate of decay; however, it adds and removes energy faster in the presence of the magnetic shear structure compared to when it has decayed away. We observe that such a forcing can induce magnetic reconnection due to field line wandering leading to the formation of magnetic islands and O-points. These reconnecting field lines spread out as the current sheet decays with time. A semi-empirical formula is derived which reasonably explains the formation and spread of O-points. We find that reconnection spreads faster with stronger forcing and longer correlation time of forcing, while the wavenumber of forcing does not have a significant effect. When the field line wandering becomes large enough, the neighboring current sheets with opposite polarity start interacting, and then the magnetic field is rapidly annihilated. This work is useful to understand how forced fluctuations can drive reconnection in large scale current structures in space and astrophysical plasmas that are not susceptible to reconnection.

  15. Driving forces for texture transformation in thin Ag films

    International Nuclear Information System (INIS)

    Ellis, Elizabeth A.; Chmielus, Markus; Lin, Ming-Tzer; Joress, Howie; Visser, Kyle; Woll, Arthur; Vinci, Richard P.; Brown, Walter L.; Baker, Shefford P.

    2016-01-01

    The well-known thickness-dependent (111)-to-(100) texture transformation in thin FCC films is usually attributed to a competition between interface and strain energies. In this model, thin films retain their (111) texture due to the lower energy of the (111) interface, while thick films transform to (100) due to the lower stiffness and thus strain energy of a (100) film. However, recent work has called this model into question, suggesting that neither the stress nor the interface energy play a dominant role in texture transformation. We investigated the driving forces involved in this transformation by using a bulge test apparatus to induce different stresses in thin Ag films under identical annealing conditions. In situ synchrotron XRD measurements show the change in texture during annealing, and reveal that applied stresses have no effect on the transformation. Stress analysis shows that differences in driving forces for texture transformation due to applied bulge pressure were significant (≈200 kJ/m 3 ), suggesting that a different, much larger driving force must be responsible. Reduction in defect energy has been proposed as an alternative. However, vacancy and dislocation densities must be exceptionally high to significantly exceed the strain energy and do not provide obvious orientation selection mechanisms. Nanotwins in reported densities are shown to provide greater driving force (≈1000 kJ/m 3 ) and may account for orientation selection. The large difference between the calculated strain and defect energies and the driving force for grain growth (21,100 kJ/m 3 ) casts doubt on the applicability of a simple thermodynamic model of texture transformation.

  16. WP/084 Measuring Industry Agglomeration and Identifying the Driving Forces

    DEFF Research Database (Denmark)

    Howard, Emma; Tarp, Finn; Newman, Carol

    Understanding industry agglomeration and its driving forces is critical for the formulation of industrial policy in developing countries. Crucial to this process is the definition and measurement of agglomeration. We propose a new measure and examine what it reveals about the importance of transp......Understanding industry agglomeration and its driving forces is critical for the formulation of industrial policy in developing countries. Crucial to this process is the definition and measurement of agglomeration. We propose a new measure and examine what it reveals about the importance...... of transport costs, labour market pooling, and technology transfer for agglomeration processes. We contrast this analysis with insights from existing measures in the literature and find very different underlying stories at work. An exceptionally rich set of data from Vietnam makes us confident that our measure...

  17. Measuring Industry Coagglomeration and Identifying the Driving Forces

    DEFF Research Database (Denmark)

    Howard, Emma; Newman, Carol; Tarp, Finn

    2015-01-01

    Understanding industry agglomeration and its driving forces is critical for the formulation of industrial policy in developing countries. Crucial to this process is the definition and measurement of agglomeration. We construct a new coagglomeration index based purely on the location of firms. We...... underlying stories at work. We conclude that in conducting analyses of this kind giving consideration to the source of agglomeration economies, employees or entrepreneurs, and finding an appropriate measure for agglomeration, are both crucial to the process of identifying agglomerative forces....

  18. Forces that Drive Nanoscale Self-assembly on Solid Surfaces

    International Nuclear Information System (INIS)

    Suo, Z.; Lu, W.

    2000-01-01

    Experimental evidence has accumulated in the recent decade that nanoscale patterns can self-assemble on solid surfaces. A two-component monolayer grown on a solid surface may separate into distinct phases. Sometimes the phases select sizes about 10 nm, and order into an array of stripes or disks. This paper reviews a model that accounts for these behaviors. Attention is focused on thermodynamic forces that drive the self-assembly. A double-welled, composition-dependent free energy drives phase separation. The phase boundary energy drives phase coarsening. The concentration-dependent surface stress drives phase refining. It is the competition between the coarsening and the refining that leads to size selection and spatial ordering. These thermodynamic forces are embodied in a nonlinear diffusion equation. Numerical simulations reveal rich dynamics of the pattern formation process. It is relatively fast for the phases to separate and select a uniform size, but exceedingly slow to order over a long distance, unless the symmetry is suitably broken

  19. Drive frequency dependent phase imaging in piezoresponse force microscopy

    International Nuclear Information System (INIS)

    Bo Huifeng; Kan Yi; Lu Xiaomei; Liu Yunfei; Peng Song; Wang Xiaofei; Cai Wei; Xue Ruoshi; Zhu Jinsong

    2010-01-01

    The drive frequency dependent piezoresponse (PR) phase signal in near-stoichiometric lithium niobate crystals is studied by piezoresponse force microscopy. It is clearly shown that the local and nonlocal electrostatic forces have a great contribution to the PR phase signal. The significant PR phase difference of the antiparallel domains are observed at the contact resonances, which is related to the electrostatic dominated electromechanical interactions of the cantilever and tip-sample system. Moreover, the modulation voltage induced frequency shift at higher eigenmodes could be attributed to the change of indention force depending on the modulation amplitude with a piezoelectric origin. The PR phase of the silicon wafer is also measured for comparison. It is certificated that the electrostatic interactions are universal in voltage modulated scanning probe microscopy and could be extended to other phase imaging techniques.

  20. Quantifying Selective Pressures Driving Bacterial Evolution Using Lineage Analysis

    Science.gov (United States)

    Lambert, Guillaume; Kussell, Edo

    2015-01-01

    Organisms use a variety of strategies to adapt to their environments and maximize long-term growth potential, but quantitative characterization of the benefits conferred by the use of such strategies, as well as their impact on the whole population's rate of growth, remains challenging. Here, we use a path-integral framework that describes how selection acts on lineages—i.e., the life histories of individuals and their ancestors—to demonstrate that lineage-based measurements can be used to quantify the selective pressures acting on a population. We apply this analysis to Escherichia coli bacteria exposed to cyclical treatments of carbenicillin, an antibiotic that interferes with cell-wall synthesis and affects cells in an age-dependent manner. While the extensive characterization of the life history of thousands of cells is necessary to accurately extract the age-dependent selective pressures caused by carbenicillin, the same measurement can be recapitulated using lineage-based statistics of a single surviving cell. Population-wide evolutionary pressures can be extracted from the properties of the surviving lineages within a population, providing an alternative and efficient procedure to quantify the evolutionary forces acting on a population. Importantly, this approach is not limited to age-dependent selection, and the framework can be generalized to detect signatures of other trait-specific selection using lineage-based measurements. Our results establish a powerful way to study the evolutionary dynamics of life under selection and may be broadly useful in elucidating selective pressures driving the emergence of antibiotic resistance and the evolution of survival strategies in biological systems.

  1. Thermal force approach to molecular evolution.

    Science.gov (United States)

    Braun, Dieter; Libchaber, Albert

    2004-06-01

    Recent experiments are discussed where temperature gradients across mesoscopic pores are shown to provide essential mechanisms for autonomous molecular evolution. On the one hand, laminar thermal convection can drive DNA replication as the molecules are continuously cycled between hot and cold regions of a chamber. On the other hand, thermophoresis can accumulate charged biopolymers in similar convection settings. The experiments show that temperature differences analogous to those across porous rocks present a robust nonequilibrium boundary condition to feed the replication and accumulation of evolving molecules. It is speculated that similar nonequilibrium conditions near porous submarine hydrothermal mounds could have triggered the origin of life. In such a scenario, the encapsulation of cells with membranes would be a later development. It is expected that detailed studies of mesoscopic boundary conditions under nonequilibrium conditions will reveal new connecting pieces in the fascinating puzzle of the origins of life.

  2. Solvent driving force ensures fast formation of a persistent and well-separated radical pair in plant cryptochrome

    DEFF Research Database (Denmark)

    Lüdemann, Gesa; Solov'yov, Ilia; Kubar, Tomás

    2015-01-01

    upon the electron transfer. This approach allows us to follow the time evolution of the electron transfer in an unbiased fashion and to reveal the molecular driving force which ensures fast electron transfer in cryptochrome guaranteeing formation of a persistent radical pair suitable...

  3. Impact assessment of land use planning driving forces on environment

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Longgao, E-mail: chenlonggao@163.com [Institute of Land Resources, Jiangsu Normal University (JSNU), Xuzhou 221116 (China); Yang, Xiaoyan [Institute of Land Resources, Jiangsu Normal University (JSNU), Xuzhou 221116 (China); School of Environment and Spatial Informatics, China University of Mining and Technology, Xuzhou 221116 (China); Chen, Longqian [School of Environment and Spatial Informatics, China University of Mining and Technology, Xuzhou 221116 (China); Li, Long [Department of Geography, Vrije Universiteit Brussel, Brussels 1050 (Belgium)

    2015-11-15

    Land use change may exert a negative impact on environmental quality. A state–impact–state (SIS) model describing a state transform under certain impacts has been integrated into land use planning (LUP) environmental impact assessment (LUPEA). This logical model is intuitive and easy to understand, but the exploration of impact is essential to establish the indicator system and to identify the scope of land use environmental impact when it is applied to a specific region. In this study, we investigated environmental driving forces from land use planning (LUPF), along with the conception, components, scope, and impact of LUPF. This method was illustrated by a case study in Zoucheng, China. Through the results, we concluded that (1) the LUPF on environment are impacts originated from the implementation of LUP on a regional environment, which are characterized by four aspects: magnitude, direction, action point, and its owner; (2) various scopes of LUPF on individual environmental elements based on different standards jointly define the final scope of LUPEA; (3) our case study in Zoucheng demonstrates the practicability of this proposed approach; (4) this method can be embedded into LUPEA with direction, magnitudes, and scopes of the LUPF on individual elements obtained, and the identified indicator system can be directly employed into LUPEA and (5) the assessment helps to identify key indicators and to set up a corresponding strategy to mitigate the negative impact of LUP on the environment, which are two important objectives of strategic environmental assessment (SEA) in LUP. - Highlights: • Environmental driving forces from land use planning (LUPF) are investigated and categorized. • Our method can obtains the direction, magnitudes and scopes of environmental driving forces. • The LUPEA scope is determined by the combination of various scopes of LUPF on individual elements. • LUPF assessment can be embedded into LUPEA. • The method can help to

  4. Variation along liquid isomorphs of the driving force for crystallization

    DEFF Research Database (Denmark)

    Pedersen, Ulf Rørbæk; Adrjanowicz, Karolina; Niss, Kristine

    2017-01-01

    at a reference temperature. More general analysis allows interpretation of experimental data for molecular liquids such as dimethyl phthalate and indomethacin, and suggests that the isomorph scaling exponent γ in these cases is an increasing function of density, although this cannot be seen in measurements......We investigate the variation of the driving force for crystallization of a supercooled liquid along isomorphs, curves along which structure and dynamics are invariant. The variation is weak, and can be predicted accurately for the Lennard-Jones fluid using a recently developed formalism and data...

  5. Driving forces and barriers for environmental technology development

    International Nuclear Information System (INIS)

    2005-01-01

    Driving forces and barriers behind development and usage of environmental technology is discussed, and also whether there are certain characteristics related to environmental innovations compared to other innovations in general. The development of environmental technology is in principle dominated by the same drivers and barriers as any other technology, but the order and strength of the various factors may be different. This examination as well as other empirical studies shows that regulations play a greater part for environmental technology than 'pure market forces'. To many participants it is important to be one step ahead of the regulations, i.e. the expected regulations are equally important as the factual ones in driving the technology development. Players in the business community express that it is important that the authorities cooperate with them when introducing new regulations. This will increase acceptance for the regulations and facilitate the necessary adjustments. The most important barrier in the development and use of the technologies studied is probably the lack of demand

  6. Segregation in ternary alloys: an interplay of driving forces

    International Nuclear Information System (INIS)

    Luyten, J.; Helfensteyn, S.; Creemers, C.

    2003-01-01

    Monte Carlo (MC) simulations combined with the constant bond energy (CBE) model are set up to explore and understand the general segregation behaviour in ternary alloys as a function of composition and more in particular the segregation to Cu-Ni-Al (1 0 0) surfaces. Besides its simplicity, allowing swift simulations, which are necessary for a first general survey over all possible compositions, one of the advantages of the CBE model lies in the possibility to clearly identify the different driving forces for segregation. All simulations are performed in the Grand Canonical Ensemble, using a new algorithm to determine the chemical potential of the components. Notwithstanding the simplicity of the CBE model, one extra feature is evidenced: depending on the values of the interatomic interaction parameters, in some regions of the ternary diagram, a single solid solution becomes thermodynamically unstable, leading to demixing into two conjugate phases. The simulations are first done for three hypothetical systems that are however representative for real alloy systems. The three systems are characterised by different sets of interatomic interaction parameters. These extensive simulations over the entire composition range of the ternary alloy yield a 'topographical' segregation map, showing distinct regions where different species segregate. These distinct domains originate from a variable interplay between the driving forces for segregation and attractive/repulsive interactions in the bulk of the alloy. The results on these hypothetical systems are very helpful for a better understanding of the segregation behaviour in Cu-Ni-Al and other ternary alloys

  7. Driving force for hydrophobic interaction at different length scales.

    Science.gov (United States)

    Zangi, Ronen

    2011-03-17

    We study by molecular dynamics simulations the driving force for the hydrophobic interaction between graphene sheets of different sizes down to the atomic scale. Similar to the prediction by Lum, Chandler, and Weeks for hard-sphere solvation [J. Phys. Chem. B 1999, 103, 4570-4577], we find the driving force to be length-scale dependent, despite the fact that our model systems do not exhibit dewetting. For small hydrophobic solutes, the association is purely entropic, while enthalpy favors dissociation. The latter is demonstrated to arise from the enhancement of hydrogen bonding between the water molecules around small hydrophobes. On the other hand, the attraction between large graphene sheets is dominated by enthalpy which mainly originates from direct solute-solute interactions. The crossover length is found to be inside the range of 0.3-1.5 nm(2) of the surface area of the hydrophobe that is eliminated in the association process. In the large-scale regime, different thermodynamic properties are scalable with this change of surface area. In particular, upon dimerization, a total and a water-induced stabilization of approximately 65 and 12 kJ/mol/nm(2) are obtained, respectively, and on average around one hydrogen bond is gained per 1 nm(2) of graphene sheet association. Furthermore, the potential of mean force between the sheets is also scalable except for interplate distances smaller than 0.64 nm which corresponds to the region around the barrier for removing the last layer of water. It turns out that, as the surface area increases, the relative height of the barrier for association decreases and the range of attraction increases. It is also shown that, around small hydrophobic solutes, the lifetime of the hydrogen bonds is longer than in the bulk, while around large hydrophobes it is the same. Nevertheless, the rearrangement of the hydrogen-bond network for both length-scale regimes is slower than in bulk water. © 2011 American Chemical Society

  8. The driving forces of landscape change in Europe

    DEFF Research Database (Denmark)

    Plieninger, Tobias; Draux, Hélène; Fagerholm, Nora

    2016-01-01

    , we find that distinct combinations of mainly political/institutional, cultural, and natural/spatial underlying drivers are determining landscape change, rather than single key drivers. Our systematic review indicates knowledge gaps that can be filled by: (a) expanding the scope of studies to include...... because landscape research is spread across many domains and disciplines. We here provide a systematic synthesis of 144 studies that identify the proximate and underlying drivers of landscape change across Europe. First, we categorize how driving forces have been addressed and find that most studies......; low Gross Domestic Product; boreal, steppic, and arctic landscapes; as well as forestland systems are underrepresented in the literature. Third, our review shows that land abandonment/extensification is the most prominent (62% of cases) among multiple proximate drivers of landscape change. Fourthly...

  9. Discharge switch driving by Lorentz force and its characteristics

    International Nuclear Information System (INIS)

    Inoue, Kunikazu; Hasegawa, Mitsuo; Ueno, Isao

    1999-01-01

    Our newly developed 'Rotary-Arc mode Discharge Switch' have featured longer life expectancy and lower inductance-wise by extremely minimizing the insulation deterioration and consumable main electrode through installation of permanent magnet, simplified construction and careful attention on the demagnetization. Resultantly, highly efficient and larger capacitive discharge switch have been available at such economical cost. In addition, by having derived an experimental formula for the driving speed of the arc, the required design parameters of the discharge switch have been determined, and then it has been well noted that any affections of electro-magnetic Lorentz force toward the starting characteristics have been negligible small. All these have made it possible to materialize such discharge switch which will satisfy the required conditions. (author)

  10. Cultural selection drives the evolution of human communication systems.

    Science.gov (United States)

    Tamariz, Monica; Ellison, T Mark; Barr, Dale J; Fay, Nicolas

    2014-08-07

    Human communication systems evolve culturally, but the evolutionary mechanisms that drive this evolution are not well understood. Against a baseline that communication variants spread in a population following neutral evolutionary dynamics (also known as drift models), we tested the role of two cultural selection models: coordination- and content-biased. We constructed a parametrized mixed probabilistic model of the spread of communicative variants in four 8-person laboratory micro-societies engaged in a simple communication game. We found that selectionist models, working in combination, explain the majority of the empirical data. The best-fitting parameter setting includes an egocentric bias and a content bias, suggesting that participants retained their own previously used communicative variants unless they encountered a superior (content-biased) variant, in which case it was adopted. This novel pattern of results suggests that (i) a theory of the cultural evolution of human communication systems must integrate selectionist models and (ii) human communication systems are functionally adaptive complex systems.

  11. Orbital Forcing driving climate variability on Tropical South Atlantic

    Science.gov (United States)

    Oliveira, A. S.; Baker, P. A.; Silva, C. G.; Dwyer, G. S.; Chiessi, C. M.; Rigsby, C. A.; Ferreira, F.

    2017-12-01

    Past research on climate response to orbital forcing in tropical South America has emphasized on high precession cycles influencing low latitude hydrologic cycles, and driving the meridional migration of Intertropical Convergence Zone (ITCZ).However, marine proxy records from the tropical Pacific Ocean showed a strong 41-ka periodicities in Pleistocene seawater temperature and productivity related to fluctuations in Earth's obliquity. It Indicates that the western Pacific ITCZ migration was influenced by combined precession and obliquity changes. To reconstruct different climate regimes over the continent and understand the orbital cycle forcing over Tropical South America climate, hydrological reconstruction have been undertaken on sediment cores located on the Brazilian continental slope, representing the past 1.6 million years. Core CDH 79 site is located on a 2345 m deep seamount on the northern Brazilian continental slope (00° 39.6853' N, 44° 20.7723' W), 320 km from modern coastline of the Maranhão Gulf. High-resolution XRF analyses of Fe, Ti, K and Ca are used to define the changes in precipitation and sedimentary input history of Tropical South America. The response of the hydrology cycle to orbital forcing was studied using spectral analysis.The 1600 ka records of dry/wet conditions presented here indicates that orbital time-scale climate change has been a dominant feature of tropical climate. We conclude that the observed oscillation reflects variability in the ITCZ activity associated with the Earth's tilt. The prevalence of the eccentricity and obliquity signals in continental hydrology proxies (Ti/Ca and Fe/K) as implicated in our precipitation records, highlights that these orbital forcings play an important role in tropics hydrologic cycles. Throughout the Quaternary abrupt shifts of tropical variability are temporally correlated with abrupt climate changes and atmospheric reorganization during Mid-Pleistocene Transition and Mid-Brunhes Events

  12. 东北老工业区生态安全动态演变过程及驱动力%Dynamic evolution and driving forces of ecological security in the Traditional Industrial Area of northeastern China

    Institute of Scientific and Technical Information of China (English)

    唐呈瑞; 逯承鹏; 杨青; 姜璐; 任婉侠; 薛冰

    2017-01-01

    Ecological security is as important as national,economic,and financial security and has become the main constraint of future socio-economic security.The Traditional Industrial Area of northeastern China is an important traditional industrial and grain production base of China,and its ecological security is related to the implementation of sustainable development strategies.Based on the emergy-ecological footprint model,the ecological security in Traditional Industrial Area of northeastern China was quantitatively evaluated from 2000 to 2014,followed by a scenario analysis on the driving forces of the ecological security using a principal component analysis method.The results showed that,the value of emergy ecological-capacity per capita decreased from 0.66 to 0.64 hm2/cap,whereas the emergy-ecological footprint increased from 10.58 to 19.85 hm2/cap,which indicated that an ecological deficit existed in the Traditional Industrial Area of northeastern China.The ecological pressure in this area increased,showing an unsustainable development trend from 2000 to 2014.The ecological pressure index and ecological security levels gradually increasing,ecological security situation is deteriorating,ecological security issues to be urgent resolved.The ecological stress tended to be serious as a result of a combination of several factors,such as social,economic,population,resource,environmental,technological level,and land use degree.Finally,effective management strategies and suggestions to improve the ecological security of the Traditional Industrial Area of northeastern China were proposed.%生态安全与国防安全、经济安全、金融安全等已具有同等重要的战略地位,并成为未来经济社会安全的主要约束.东北老工业区作为我国重要的老工业基地及粮食生产基地,其生态安全状况关系着中国可持续发展战略的实施.采用能值-生态足迹模型,对东北老工业区2000-2014年生态安全动态演变过程进行

  13. Modeling the Evolution of Female Meiotic Drive in Maize

    Directory of Open Access Journals (Sweden)

    David W. Hall

    2018-01-01

    Full Text Available Autosomal drivers violate Mendel’s law of segregation in that they are overrepresented in gametes of heterozygous parents. For drivers to be polymorphic within populations rather than fixing, their transmission advantage must be offset by deleterious effects on other fitness components. In this paper, we develop an analytical model for the evolution of autosomal drivers that is motivated by the neocentromere drive system found in maize. In particular, we model both the transmission advantage and deleterious fitness effects on seed viability, pollen viability, seed to adult survival mediated by maternal genotype, and seed to adult survival mediated by offspring genotype. We derive general, biologically intuitive conditions for the four most likely evolutionary outcomes and discuss the expected evolution of autosomal drivers given these conditions. Finally, we determine the expected equilibrium allele frequencies predicted by the model given recent estimates of fitness components for all relevant genotypes and show that the predicted equilibrium is within the range observed in maize land races for levels of drive at the low end of what has been observed.

  14. Natural selection drives the evolution of ant life cycles.

    Science.gov (United States)

    Wilson, Edward O; Nowak, Martin A

    2014-09-02

    The genetic origin of advanced social organization has long been one of the outstanding problems of evolutionary biology. Here we present an analysis of the major steps in ant evolution, based for the first time, to our knowledge, on combined recent advances in paleontology, phylogeny, and the study of contemporary life histories. We provide evidence of the causal forces of natural selection shaping several key phenomena: (i) the relative lateness and rarity in geological time of the emergence of eusociality in ants and other animal phylads; (ii) the prevalence of monogamy at the time of evolutionary origin; and (iii) the female-biased sex allocation observed in many ant species. We argue that a clear understanding of the evolution of social insects can emerge if, in addition to relatedness-based arguments, we take into account key factors of natural history and study how natural selection acts on alleles that modify social behavior.

  15. Petroleum Development in Russian Barents sea: Driving Forces and Constraints

    International Nuclear Information System (INIS)

    Moe, Arild; Joergensen, Anne-Kristin

    2000-01-01

    The potential of the Barents Sea for petroleum production has attracted interest for many years. In the Russian sector of this ocean, enormous gas finds and substantial oil resources have now been proven, and the first real licensing for field development in the area has just begun. Despite the area's potential, there are strong conflicts of interest. The report examines the forces alternatively driving and hindering offshore hydrocarbon development in the Russian sector of the Barents Sea. It describes exploration activities beginning during the Soviet period and extending to the present. The status of the major development projects financed in part with foreign capital, and conflicting regional and central government interests involved in such development, is described and evaluated. Coverage includes a discussion of the various regional interests in petroleum activities, with a particular focus on the conversion of naval yards in the area and the emergence of Rosshelf, an oil/gas conglomerate formed to facilitate such conversion. It also reviews the planned licensing rounds and the results of the first round. Finally, it discusses supplies from the Barents Sea in the context of overall Russian energy supply and energy development strategies. (author)

  16. Probabilistic analysis for identifying the driving force of protein folding

    Science.gov (United States)

    Tokunaga, Yoshihiko; Yamamori, Yu; Matubayasi, Nobuyuki

    2018-03-01

    Toward identifying the driving force of protein folding, energetics was analyzed in water for Trp-cage (20 residues), protein G (56 residues), and ubiquitin (76 residues) at their native (folded) and heat-denatured (unfolded) states. All-atom molecular dynamics simulation was conducted, and the hydration effect was quantified by the solvation free energy. The free-energy calculation was done by employing the solution theory in the energy representation, and it was seen that the sum of the protein intramolecular (structural) energy and the solvation free energy is more favorable for a folded structure than for an unfolded one generated by heat. Probabilistic arguments were then developed to determine which of the electrostatic, van der Waals, and excluded-volume components of the interactions in the protein-water system governs the relative stabilities between the folded and unfolded structures. It was found that the electrostatic interaction does not correspond to the preference order of the two structures. The van der Waals and excluded-volume components were shown, on the other hand, to provide the right order of preference at probabilities of almost unity, and it is argued that a useful modeling of protein folding is possible on the basis of the excluded-volume effect.

  17. Salticid predation as one potential driving force of ant mimicry in jumping spiders

    Science.gov (United States)

    Huang, Jin-Nan; Cheng, Ren-Chung; Li, Daiqin; Tso, I-Min

    2011-01-01

    Many spiders possess myrmecomorphy, and species of the jumping spider genus Myrmarachne exhibit nearly perfect ant mimicry. Most salticids are diurnal predators with unusually high visual acuity that prey on various arthropods, including conspecifics. In this study, we tested whether predation pressure from large jumping spiders is one possible driving force of perfect ant mimicry in jumping spiders. The results showed that small non-ant-mimicking jumping spiders were readily treated as prey by large ones (no matter whether heterospecific or conspecific) and suffered high attack and mortality rates. The size difference between small and large jumping spiders significantly affected the outcomes of predatory interactions between them: the smaller the juvenile jumping spiders, the higher the predation risk from large ones. The attack and mortality rates of ant-mimicking jumping spiders were significantly lower than those of non-ant-mimicking jumping spiders, indicating that a resemblance to ants could provide protection against salticid predation. However, results of multivariate behavioural analyses showed that the responses of large jumping spiders to ants and ant-mimicking salticids differed significantly. Results of this study indicate that predation pressure from large jumping spiders might be one selection force driving the evolution of nearly perfect myrmecomorphy in spiders and other arthropods. PMID:20961898

  18. The Impact of Evolutionary Driving Forces on Human Complex Diseases: A Population Genetics Approach

    Directory of Open Access Journals (Sweden)

    Amr T. M. Saeb

    2016-01-01

    Full Text Available Investigating the molecular evolution of human genome has paved the way to understand genetic adaptation of humans to the environmental changes and corresponding complex diseases. In this review, we discussed the historical origin of genetic diversity among human populations, the evolutionary driving forces that can affect genetic diversity among populations, and the effects of human movement into new environments and gene flow on population genetic diversity. Furthermore, we presented the role of natural selection on genetic diversity and complex diseases. Then we reviewed the disadvantageous consequences of historical selection events in modern time and their relation to the development of complex diseases. In addition, we discussed the effect of consanguinity on the incidence of complex diseases in human populations. Finally, we presented the latest information about the role of ancient genes acquired from interbreeding with ancient hominids in the development of complex diseases.

  19. Driving forces of Indian summer monsoon on Milankovitch and sub-Milankovitch time scales: A review

    Digital Repository Service at National Institute of Oceanography (India)

    Naidu, P.D.

    A scientific consensus exists that tectonic evolution of Himalaya is the main cause of monsoon initiation and evolution in southeast Asia. Several forcing factors such as tectonic, solar insolation, latent heat transport, albedo of the earth surface...

  20. Why men matter: mating patterns drive evolution of human lifespan.

    Directory of Open Access Journals (Sweden)

    Shripad D Tuljapurkar

    2007-08-01

    Full Text Available Evolutionary theory predicts that senescence, a decline in survival rates with age, is the consequence of stronger selection on alleles that affect fertility or mortality earlier rather than later in life. Hamilton quantified this argument by showing that a rare mutation reducing survival is opposed by a selective force that declines with age over reproductive life. He used a female-only demographic model, predicting that female menopause at age ca. 50 yrs should be followed by a sharp increase in mortality, a "wall of death." Human lives obviously do not display such a wall. Explanations of the evolution of lifespan beyond the age of female menopause have proven difficult to describe as explicit genetic models. Here we argue that the inclusion of males and mating patterns extends Hamilton's theory and predicts the pattern of human senescence. We analyze a general two-sex model to show that selection favors survival for as long as men reproduce. Male fertility can only result from matings with fertile females, and we present a range of data showing that males much older than 50 yrs have substantial realized fertility through matings with younger females, a pattern that was likely typical among early humans. Thus old-age male fertility provides a selective force against autosomal deleterious mutations at ages far past female menopause with no sharp upper age limit, eliminating the wall of death. Our findings illustrate the evolutionary importance of males and mating preferences, and show that one-sex demographic models are insufficient to describe the forces that shape human senescence.

  1. Small and Medium Sized Reactors: Driving Forces and Technology Development

    International Nuclear Information System (INIS)

    Gowin, P.J.; Kupitz, J.

    2002-01-01

    There will be growing demands for energy in the coming decades. One aspect of particular importance is that prospects for nuclear energy will to a considerable extent be influenced by developing countries. Since population growth will occur primarily in developing countries nuclear energy cannot play a significant global role without being a viable option in these countries. Since new power plants to be built will have to be compatible with regional electricity grids, this may result in a greater focus on plants in the small and medium range, defined by the International Atomic Energy Agency (IAEA) to produce up to 700 Megawatt of electrical power. This paper first examines the driving forces that could influence the development of nuclear energy in general and of Small and Medium Sized Reactors (SMRs) in particular in the next decades and identifies key factors in that process. Concerns over climate change may to a certain extent influence the discussion on future energy options. Other factors of equal importance for the future of nuclear are a continued emphasis on maintaining high safety standards, the implementation of acceptable solutions for spent fuel and radioactive waste disposal and a globally accepted non-proliferation regime, factors that may in turn have an impact on public acceptance. Economic competitiveness of nuclear energy is an additional important factor, and without being commercially viable, no energy source can in the long run represent a major and stable component in a competitive energy sector. The introduction of SMRs in developing countries poses additional challenges, such as investment limitations. Technology development plays an important role in keeping the nuclear option open for countries wishing to use nuclear reactors to meet their energy needs, and advances in reactor design will be important to enable a significant nuclear component in developing countries. This paper considers the contribution that nuclear science and

  2. A balanced ATP driving force module for enhancing photosynthetic biosynthesis of 3-hydroxybutyrate from CO2.

    Science.gov (United States)

    Ku, Jason T; Lan, Ethan I

    2018-03-01

    Using engineered photoautotrophic microorganisms for the direct chemical synthesis from CO 2 is an attractive direction for both sustainability and CO 2 mitigation. However, the behaviors of non-native metabolic pathways may be difficult to control due to the different intracellular contexts between natural and heterologous hosts. While most metabolic engineering efforts focus on strengthening driving forces in pathway design to favor biochemical production in these organisms, excessive driving force may be detrimental to product biosynthesis due to imbalanced cellular intermediate distribution. In this study, an ATP-hydrolysis based driving force module was engineered into cyanobacterium Synechococcus elongatus PCC 7942 to produce 3-hydroxybutyrate (3HB), a valuable chemical feedstock for the synthesis of biodegradable plastics and antibiotics. However, while the ATP driving force module is effective for increasing product formation, uncontrolled accumulation of intermediate metabolites likely led to metabolic imbalance and thus to cell growth inhibition. Therefore, the ATP driving force module was reengineered by providing a reversible outlet for excessive carbon flux. Upon expression of this balanced ATP driving force module with 3HB biosynthesis, engineered strain produced 3HB with a cumulative titer of 1.2 g/L, a significant increase over the initial strain. This result highlighted the importance of pathway reversibility as an effective design strategy for balancing driving force and intermediate accumulation, thereby achieving a self-regulated control for increased net flux towards product biosynthesis. Copyright © 2018 International Metabolic Engineering Society. Published by Elsevier Inc. All rights reserved.

  3. Bursts of transposable elements as an evolutionary driving force

    Czech Academy of Sciences Publication Activity Database

    Belyayev, Alexander

    2014-01-01

    Roč. 27, č. 12 (2014), s. 2573-2584 ISSN 1010-061X Institutional support: RVO:67985939 Keywords : evolution * genome * marginal populations * speciation * transposable elements Subject RIV: EF - Botanics Impact factor: 3.232, year: 2014

  4. [The motive force of evolution based on the principle of organismal adjustment evolution.].

    Science.gov (United States)

    Cao, Jia-Shu

    2010-08-01

    From the analysis of the existing problems of the prevalent theories of evolution, this paper discussed the motive force of evolution based on the knowledge of the principle of organismal adjustment evolution to get a new understanding of the evolution mechanism. In the guide of Schrodinger's theory - "life feeds on negative entropy", the author proposed that "negative entropy flow" actually includes material flow, energy flow and information flow, and the "negative entropy flow" is the motive force for living and development. By modifying my own theory of principle of organismal adjustment evolution (not adaptation evolution), a new theory of "regulation system of organismal adjustment evolution involved in DNA, RNA and protein interacting with environment" is proposed. According to the view that phylogenetic development is the "integral" of individual development, the difference of negative entropy flow between organisms and environment is considered to be a motive force for evolution, which is a new understanding of the mechanism of evolution. Based on such understanding, evolution is regarded as "a changing process that one subsystem passes all or part of its genetic information to the next generation in a larger system, and during the adaptation process produces some new elements, stops some old ones, and thereby lasts in the larger system". Some other controversial questions related to evolution are also discussed.

  5. Effect of a powered drive on pushing and pulling forces when transporting bariatric hospital beds.

    Science.gov (United States)

    Wiggermann, Neal

    2017-01-01

    Powered drives designed to assist with moving hospital beds are commercially available but no studies have evaluated whether they reduce the push and pull forces likely contributing to injury in caregivers. This study measured hand forces of 10 caregivers maneuvering a manual and powered bariatric bed through simulated hospital environments (hallway, elevator, and ramp). Peak push and pull forces exceeded previously established psychophysical limits for all activities with the manual bed. For the powered bed, peak forces were significantly (p pushing did not differ between beds. Powered drive may reduce the risk of injury or the number of caregivers needed for transport. Copyright © 2016 Elsevier Ltd. All rights reserved.

  6. An arms race between producers and scroungers can drive the evolution of social cognition

    Science.gov (United States)

    2014-01-01

    The “social intelligence hypothesis” states that the need to cope with complexities of social life has driven the evolution of advanced cognitive abilities. It is usually invoked in the context of challenges arising from complex intragroup structures, hierarchies, and alliances. However, a fundamental aspect of group living remains largely unexplored as a driving force in cognitive evolution: the competition between individuals searching for resources (producers) and conspecifics that parasitize their findings (scroungers). In populations of social foragers, abilities that enable scroungers to steal by outsmarting producers, and those allowing producers to prevent theft by outsmarting scroungers, are likely to be beneficial and may fuel a cognitive arms race. Using analytical theory and agent-based simulations, we present a general model for such a race that is driven by the producer–scrounger game and show that the race’s plausibility is dramatically affected by the nature of the evolving abilities. If scrounging and scrounging avoidance rely on separate, strategy-specific cognitive abilities, arms races are short-lived and have a limited effect on cognition. However, general cognitive abilities that facilitate both scrounging and scrounging avoidance undergo stable, long-lasting arms races. Thus, ubiquitous foraging interactions may lead to the evolution of general cognitive abilities in social animals, without the requirement of complex intragroup structures. PMID:24822021

  7. Evolution of Soviet Theater Nuclear Forces

    International Nuclear Information System (INIS)

    Atkeson, E.B.

    1994-01-01

    Soviet theater nuclear forces were a major pillar of Soviet superpower strength, rising sharply under Krushchev in the latter 1950s to their zenith under Brezhnev twenty years later. Most recently they have begun their decline under Gorbachev, and while not yet facing extinction, may be headed for a much reduced role under the new thinking in the USSR. This paper deals with the Soviet TNF in six periods of their life: The Post-war Stalin Period (1945-1953), the Post-Stalin Period (1953-1955), The Transition Period (1955-1959), The Period of Nuclear Revolution (1960-1964), The Period of Modern TNF Planning (1965-1980), and The Period of Non-nuclear Planning (1980-1987)

  8. Russia's strategic forces: policy, evolution and prospects

    International Nuclear Information System (INIS)

    Fedorov, Y.E.

    2005-01-01

    The well-know 1980 joke, according to which the Soviet Union was nothing else than Upper Volta armed with nuclear missiles, was literally not quite correct. On top of its nuclear missiles, the former Soviet Union had a lot of nuclear and conventional submarines, combat aircraft, tanks and other deadly weaponry. Yet it was true that the global ambitions of the high military commanders, the captains of the Soviet military-industrial complex, and the CPSU chiefs burdened the weak Soviet economy. In fact, military related expenditures, mounting up to 25 percent of the USSR GDP, were among the most fundamental causes of the Soviet economic and political collapse. By the 1990, the joke had become even more credible. Yeltzin Russia, affected by severe economic and social crises, kept only two attributes of its former superpower status: a seat on the UN Security Council and a substantial yet decreasing nuclear arsenal. Russia recent economic revival and political transformation, from the embryonic and chaotic democracy of Yeltzin into an authoritarian regime pillaring itself on the security sector and the post-Soviet bureaucracy, provoke critical questions in regards to the nation future role in the emerging international system, primarily in the Eurasian region. Two of these questions are whether Russia will be able to maintain the world second largest strategic nuclear arsenal, and how Russia ruling class will view the roles and missions of nuclear weapons. To answer these questions it is necessary to assess (a) the governmental policy that determines the development of Russian nuclear force; (b) the structure and quantity of the current nuclear force; and (c) the capacity of missile and submarine-building industries. (author)

  9. Social Innovation : Driving Forces of Social Innovation in MNC

    OpenAIRE

    Tam, Hoising; Osadcha, Liudmyla

    2017-01-01

    Multinational Corporations (MNCs) currently face not only a dynamic business environment and challenging profit target, but also increased expectations from the public to take responsibility for addressing social, economic, and environmental issues. There is a tendency that the leading companies in the global market, especially MNCs, put more effort to the Social Innovation (SI). This study is to investigate what drives the MNCs to be involved in social innovation. In order to find out the re...

  10. Remark on the role of the driving force in BWR instability

    International Nuclear Information System (INIS)

    Dykin, V.; Pazsit, I.

    2009-01-01

    Simple models of BWR instability, used e.g. in understanding the role of the various oscillation modes in the overall stability of the plant, assume that each oscillation mode can be described by a second order system (a damped harmonic oscillator) driven by a white noise driving force. Change of the decay ratio (DR) of the observed signal is, as a rule, associated with the changing of the parameters of the damped oscillator, mainly its damping coefficient, and is interpreted in terms of the change of the stability of the system. However, conceptually, one cannot exclude cases when the change of the response of a driven damped oscillator is due to the change of the properties of the driving force. In this work we investigate the effect of a non-white driving force on the behaviour of the system. A question of interest is how changes of the spectrum of the driving force influence the observed autocorrelation function (ACF) of the resulting signal. Hence we calculate the response of a damped harmonic oscillator driven by a non-white driving force, corresponding to the reactivity effect of propagating density fluctuations in two-phase flow. It is shown how in some special cases such a driving force, when interpreting the neutron noise as if induced by a white noise driving source, can lead to an erroneous conclusion regarding the stability of the system. It is also concluded that in the practically interesting cases the effect of the coloured driving force, arising from propagating density fluctuations, is negligible.

  11. Boomers and seniors: The driving force behind leisure participation

    Science.gov (United States)

    Lynda J. Sperazza; Priya Banerjee

    2010-01-01

    The 76 million Americans in the Baby Boomer population are the force behind the changing demographic picture of society today. Boomers' spending habits and lifestyle choices will also have a powerful influence on retirement and leisure in the coming decades. Boomers will redefine retirement and are expected to demand more than current senior programs and...

  12. An introductory handbook for state task forces to combat drunk driving.

    Science.gov (United States)

    1983-01-01

    In June 1982 Governor Robb created a task force to identify and assess efforts under way in Virginia to address the problem of drunken driving and to make recommendations. This booklet was prepared to assist the task force in its deliberations.

  13. COMPETITIVENESS IN SERVICES, DRIVING FORCE OF ECONOMIC DEVELOPMENT

    OpenAIRE

    RAMONA PÎRVU; MARIA DANATIE ENESCU

    2012-01-01

    The competitiveness of a nation is ensured by the profitable activity of firms. They strengthen their position in the domestic and international markets through global strategies whose purpose is to increase productivity and maintain it at a high level. For this, the company must take into account both the internal economic environment which ensures operating conditions and the external economic environment’s development. The five competitive forces determine the industry’s profitability beca...

  14. Position and force control of a vehicle with two or more steerable drive wheels

    Energy Technology Data Exchange (ETDEWEB)

    Reister, D.B.; Unseren, M.A.

    1992-10-01

    When a vehicle with two or more steerable drive wheels is traveling in a circle, the motion of the wheels is constrained. The wheel translational velocity divided by the radius to the center of rotation must be the same for all wheels. When the drive wheels are controlled independently using position control, the motion of the wheels may violate the constraints and the wheels may slip. Consequently, substantial errors can occur in the orientation of the vehicle. A vehicle with N drive wheels has (N - 1) constraints and one degree of freedom. We have developed a new approach to the control of a vehicle with N steerable drive wheels. The novel aspect of our approach is the use of force control. To control the vehicle, we have one degree of freedom for the position on the circle and (N - 1) forces that can be used to reduce errors. Recently, Kankaanranta and Koivo developed a control architecture that allows the force and position degrees of freedom to be decoupled. In the work of Kankaanranta and Koivo the force is an exogenous input. We have made the force endogenous by defining the force in terms of the errors in satisfying the rigid body kinematic constraints. We have applied the control architecture to the HERMIES-III robot and have measured a dramatic reduction in error (more than a factor of 20) compared to motions without force control.

  15. Repeated evolution of soldier sub-castes suggests parasitism drives social complexity in stingless bees.

    Science.gov (United States)

    Grüter, Christoph; Segers, Francisca H I D; Menezes, Cristiano; Vollet-Neto, Ayrton; Falcón, Tiago; von Zuben, Lucas; Bitondi, Márcia M G; Nascimento, Fabio S; Almeida, Eduardo A B

    2017-02-23

    The differentiation of workers into morphological castes represents an important evolutionary innovation that is thought to improve division of labor in insect societies. Given the potential benefits of task-related worker differentiation, it is puzzling that physical worker castes, such as soldiers, are extremely rare in social bees and absent in wasps. Following the recent discovery of soldiers in a stingless bee, we studied the occurrence of worker differentiation in 28 stingless bee species from Brazil and found that several species have specialized soldiers for colony defence. Our results reveal that worker differentiation evolved repeatedly during the last ~ 25 million years and coincided with the emergence of parasitic robber bees, a major threat to many stingless bee species. Furthermore, our data suggest that these robbers are a driving force behind the evolution of worker differentiation as targets of robber bees are four times more likely to have nest guards of increased size than non-targets. These findings reveal unexpected diversity in the social organization of stingless bees.Although common in ants and termites, worker differentiation into physical castes is rare in social bees and unknown in wasps. Here, Grüter and colleagues find a guard caste in ten species of stingless bees and show that the evolution of the guard caste is associated with parasitization by robber bees.

  16. Crack Driving Forces in a Multilayered Coating System for Ceramic Matrix Composite Substrates

    Science.gov (United States)

    Ghosn, Louis J.; Zhu, Dongming; Miller, Robert A.

    2005-01-01

    The effects of the top coating thickness, modulus and shrinkage strains on the crack driving forces for a baseline multilayer Yttria-Stabilized-Zirconia/Mullite/Si thermal and environment barrier coating (TEBC) system for SiC/SiC ceramic matrix composite substrates are determined for gas turbine applications. The crack driving forces increase with increasing modulus, and a low modulus thermal barrier coating material (below 10 GPa) will have no cracking issues under the thermal gradient condition analyzed. Since top coating sintering increases the crack driving forces with time, highly sintering resistant coatings are desirable to maintain a low tensile modulus and maintain a low crack driving force with time. Finite element results demonstrated that an advanced TEBC system, such as ZrO2/HfO2, which possesses improved sintering resistance and high temperature stability, exhibited excellent durability. A multi-vertical cracked structure with fine columnar spacing is an ideal strain tolerant coating capable of reducing the crack driving forces to an acceptable level even with a high modulus of 50 GPa.

  17. Evaluating the Energetic Driving Force for Cocrystal Formation.

    Science.gov (United States)

    Taylor, Christopher R; Day, Graeme M

    2018-02-07

    We present a periodic density functional theory study of the stability of 350 organic cocrystals relative to their pure single-component structures, the largest study of cocrystals yet performed with high-level computational methods. Our calculations demonstrate that cocrystals are on average 8 kJ mol -1 more stable than their constituent single-component structures and are very rarely (intuition, the presence of hydrogen or halogen bond interactions is not necessarily a good predictor of stability. Finally, we investigate the correlation of the relative stability with simple chemical descriptors: changes in packing efficiency and hydrogen bond strength. We find some broad qualitative agreement with chemical intuition-more densely packed cocrystals with stronger hydrogen bonding tend to be more stable-but the relationship is weak, suggesting that such simple descriptors do not capture the complex balance of interactions driving cocrystallization. Our conclusions suggest that while cocrystallization is often a thermodynamically favorable process, it remains difficult to formulate general rules to guide synthesis, highlighting the continued importance of high-level computation in predicting and rationalizing such systems.

  18. The Driving Forces of Cultural Complexity : Neanderthals, Modern Humans, and the Question of Population Size.

    Science.gov (United States)

    Fogarty, Laurel; Wakano, Joe Yuichiro; Feldman, Marcus W; Aoki, Kenichi

    2017-03-01

    The forces driving cultural accumulation in human populations, both modern and ancient, are hotly debated. Did genetic, demographic, or cognitive features of behaviorally modern humans (as opposed to, say, early modern humans or Neanderthals) allow culture to accumulate to its current, unprecedented levels of complexity? Theoretical explanations for patterns of accumulation often invoke demographic factors such as population size or density, whereas statistical analyses of variation in cultural complexity often point to the importance of environmental factors such as food stability, in determining cultural complexity. Here we use both an analytical model and an agent-based simulation model to show that a full understanding of the emergence of behavioral modernity, and the cultural evolution that has followed, depends on understanding and untangling the complex relationships among culture, genetically determined cognitive ability, and demographic history. For example, we show that a small but growing population could have a different number of cultural traits from a shrinking population with the same absolute number of individuals in some circumstances.

  19. Adaptive processes drive ecomorphological convergent evolution in antwrens (Thamnophilidae).

    Science.gov (United States)

    Bravo, Gustavo A; Remsen, J V; Brumfield, Robb T

    2014-10-01

    Phylogenetic niche conservatism (PNC) and convergence are contrasting evolutionary patterns that describe phenotypic similarity across independent lineages. Assessing whether and how adaptive processes give origin to these patterns represent a fundamental step toward understanding phenotypic evolution. Phylogenetic model-based approaches offer the opportunity not only to distinguish between PNC and convergence, but also to determine the extent that adaptive processes explain phenotypic similarity. The Myrmotherula complex in the Neotropical family Thamnophilidae is a polyphyletic group of sexually dimorphic small insectivorous forest birds that are relatively homogeneous in size and shape. Here, we integrate a comprehensive species-level molecular phylogeny of the Myrmotherula complex with morphometric and ecological data within a comparative framework to test whether phenotypic similarity is described by a pattern of PNC or convergence, and to identify evolutionary mechanisms underlying body size and shape evolution. We show that antwrens in the Myrmotherula complex represent distantly related clades that exhibit adaptive convergent evolution in body size and divergent evolution in body shape. Phenotypic similarity in the group is primarily driven by their tendency to converge toward smaller body sizes. Differences in body size and shape across lineages are associated to ecological and behavioral factors. © 2014 The Author(s). Evolution © 2014 The Society for the Study of Evolution.

  20. Hypoxia: The Force that Drives Chronic Kidney Disease

    Science.gov (United States)

    Fu, Qiangwei; Colgan, Sean P; Shelley, Carl Simon

    2016-01-01

    In the United States the prevalence of end-stage renal disease (ESRD) reached epidemic proportions in 2012 with over 600,000 patients being treated. The rates of ESRD among the elderly are disproportionally high. Consequently, as life expectancy increases and the baby-boom generation reaches retirement age, the already heavy burden imposed by ESRD on the US health care system is set to increase dramatically. ESRD represents the terminal stage of chronic kidney disease (CKD). A large body of evidence indicating that CKD is driven by renal tissue hypoxia has led to the development of therapeutic strategies that increase kidney oxygenation and the contention that chronic hypoxia is the final common pathway to end-stage renal failure. Numerous studies have demonstrated that one of the most potent means by which hypoxic conditions within the kidney produce CKD is by inducing a sustained inflammatory attack by infiltrating leukocytes. Indispensable to this attack is the acquisition by leukocytes of an adhesive phenotype. It was thought that this process resulted exclusively from leukocytes responding to cytokines released from ischemic renal endothelium. However, recently it has been demonstrated that leukocytes also become activated independent of the hypoxic response of endothelial cells. It was found that this endothelium-independent mechanism involves leukocytes directly sensing hypoxia and responding by transcriptional induction of the genes that encode the β2-integrin family of adhesion molecules. This induction likely maintains the long-term inflammation by which hypoxia drives the pathogenesis of CKD. Consequently, targeting these transcriptional mechanisms would appear to represent a promising new therapeutic strategy. PMID:26847481

  1. Automatic Clustering Using FSDE-Forced Strategy Differential Evolution

    Science.gov (United States)

    Yasid, A.

    2018-01-01

    Clustering analysis is important in datamining for unsupervised data, cause no adequate prior knowledge. One of the important tasks is defining the number of clusters without user involvement that is known as automatic clustering. This study intends on acquiring cluster number automatically utilizing forced strategy differential evolution (AC-FSDE). Two mutation parameters, namely: constant parameter and variable parameter are employed to boost differential evolution performance. Four well-known benchmark datasets were used to evaluate the algorithm. Moreover, the result is compared with other state of the art automatic clustering methods. The experiment results evidence that AC-FSDE is better or competitive with other existing automatic clustering algorithm.

  2. Information driving force and its application in agent-based modeling

    Science.gov (United States)

    Chen, Ting-Ting; Zheng, Bo; Li, Yan; Jiang, Xiong-Fei

    2018-04-01

    Exploring the scientific impact of online big-data has attracted much attention of researchers from different fields in recent years. Complex financial systems are typical open systems profoundly influenced by the external information. Based on the large-scale data in the public media and stock markets, we first define an information driving force, and analyze how it affects the complex financial system. The information driving force is observed to be asymmetric in the bull and bear market states. As an application, we then propose an agent-based model driven by the information driving force. Especially, all the key parameters are determined from the empirical analysis rather than from statistical fitting of the simulation results. With our model, both the stationary properties and non-stationary dynamic behaviors are simulated. Considering the mean-field effect of the external information, we also propose a few-body model to simulate the financial market in the laboratory.

  3. COMPETITIVENESS IN SERVICES, DRIVING FORCE OF ECONOMIC DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    RAMONA PÎRVU

    2012-12-01

    Full Text Available The competitiveness of a nation is ensured by the profitable activity of firms. They strengthen their position in the domestic and international markets through global strategies whose purpose is to increase productivity and maintain it at a high level. For this, the company must take into account both the internal economic environment which ensures operating conditions and the external economic environment’s development. The five competitive forces determine the industry’s profitability because they configure firms’ selling prices, production costs and investments needed to be competitive in the field. The threat of new competitors limits the potential profit since they involve new production units and the opportunities for market expansion. Economic strength of the buyers and bidders attracts profits to them. Rivalry among existing competitors erodes profits by increasing costs of competition (like advertising, selling expenses or those required for research and development. The presence of substitutive goods or services limits competitors’ prices through buyers’ transfer phenomena limiting and eroding market share of industry / firm in the total production output.

  4. On Optimizing Steering Performance of Multi-axle Vehicle Based on Driving Force Control

    Directory of Open Access Journals (Sweden)

    Wu Zhicheng

    2017-01-01

    Full Text Available The steering performance of multi-axle vehicle with independent driving system is affected by the distribution of the wheel driving force. A nonlinear vehicle dynamics model including magic formula tire model for describing 11 DoF four-axle vehicle with dual-front-axle-steering (DFAS system was presented. The influence of different driving force distribution scheme on the steering performance of the vehicle was analyzed. A control strategy for improving the steady response and transient response of the vehicle steering is proposed. The results show: For the steady response, setting different drive force for internal and external wheels according to the actual steering characteristics of the vehicle can effectively improve its steering characteristics; For the transient response, adopting the zero sideslip angle control strategy and using the PID control algorithm to control the driving force of the outside wheel of tear-two-axle, under angle step input, the vehicle sideslip angle can quickly stabilize to 0 and yaw rate also significantly decreases.

  5. Preliminary Experimental Results for Indirect Vector-Control of Induction Motor Drives with Forced Dynamics

    Directory of Open Access Journals (Sweden)

    Jan Vittek

    2003-01-01

    Full Text Available The contribution presents an extension of indirect vector control of electric drives employing induction motors to 'Forced Dynamic Control'. This method of control offers an accurate realisation of dynamic response profiles, which can be selected by the user. The developed system can be integrated into a drive with a shaft position encoder or a shaft sensoriess drive, in which only the stator currents are measured. The applied stator voltages are determined by a computed inverter switching algorithm. Simulation results and preliminary experimental results for indirect vector control of an idle running induction motor indicate good agreement with the theoretical predictions.

  6. Development of an innovative reflector drive mechanism using magnetic repulsion force for 4S reactor

    International Nuclear Information System (INIS)

    Tsuji, K.; Watanabe, M.; Inagaki, H.; Nishikawa, A.; Takahashi, H.; Wakamatsu, M.; Matsumiya, H.; Nishiguchi, Y.

    2001-01-01

    A small sized fast reactor 4S: (Super Safe Small and Simple) which has a core of 10 - 30 years life time is controlled by reflectors. The reflector is required to be risen at very low speed to make up for the reactivity swing during operation. This report shows the development of an innovative reflector drive mechanism using magnetic repulsion force that can move at a several micrometer per one step. This drive mechanism has a passive shut down capability, and can eliminate reflector drive line. (author)

  7. Study on electromagnetism force of CARR control rod drive mechanism experimental machine

    International Nuclear Information System (INIS)

    Zhu Xuewei; Zhen Jianxiao; Wang Yulin; Jia Yueguang; Yang Kun; Yin Haozhe

    2015-01-01

    With the aim of acquiring electromagnetic force and electromagnetic field distributions of control rod drive mechanism (CRDM) in China Advanced Research Reactor (CARR), the force analysis on the CRDM was taken. Manufacturing the experimental machine, the electromagnetic force experiment was taken on it. The electromagnetic field and electromagnetic force simulation analyses of experimental machine were taken, working out distribution data of electromagnetic force and magnetic induction intensity distribution curve, and the effects of permanent magnetic field on electromagnetic field and structure parameters on electromagnetic force. The simulation value is accord with experiment value, the research results provide a reference to electromagnetic force study on CRDM in CARR, and also provide a reference to design of the same type CRDM. (authors)

  8. Evolution of resistance against CRISPR/Cas9 gene drive

    OpenAIRE

    Clark, Andrew; Unckless, Robert; Messer, Philipp

    2016-01-01

    CRISPR/Cas9 gene drive (CGD) promises to be a highly adaptable approach for spreading genetically engineered alleles throughout a species, even if those alleles impair reproductive success. CGD has been shown to be effective in laboratory crosses of insects, yet it remains unclear to what extent potential resistance mechanisms will affect the dynamics of this process in large natural populations. Here we develop a comprehensive population genetic framework for modeling CGD dynamics, which inc...

  9. Estimation of Muscle Force Based on Neural Drive in a Hemispheric Stroke Survivor.

    Science.gov (United States)

    Dai, Chenyun; Zheng, Yang; Hu, Xiaogang

    2018-01-01

    Robotic assistant-based therapy holds great promise to improve the functional recovery of stroke survivors. Numerous neural-machine interface techniques have been used to decode the intended movement to control robotic systems for rehabilitation therapies. In this case report, we tested the feasibility of estimating finger extensor muscle forces of a stroke survivor, based on the decoded descending neural drive through population motoneuron discharge timings. Motoneuron discharge events were obtained by decomposing high-density surface electromyogram (sEMG) signals of the finger extensor muscle. The neural drive was extracted from the normalized frequency of the composite discharge of the motoneuron pool. The neural-drive-based estimation was also compared with the classic myoelectric-based estimation. Our results showed that the neural-drive-based approach can better predict the force output, quantified by lower estimation errors and higher correlations with the muscle force, compared with the myoelectric-based estimation. Our findings suggest that the neural-drive-based approach can potentially be used as a more robust interface signal for robotic therapies during the stroke rehabilitation.

  10. The marriage between welfare services and tourism - A driving force for innovation?

    DEFF Research Database (Denmark)

    Hjalager, Anne Mette

    2006-01-01

    -based sectors are well connected with other sectors, including the voluntary sector. Both internal and external driving forces are continuously challenging the Danish welfare model. The pressures and the opportunities are transmitted to tourism, albeit not uniformly. There are good reasons for commercial...

  11. Transmission of government spending shocks in the Euro area: time variation and driving forces

    NARCIS (Netherlands)

    Kirchner, M.; Cimadomo, J.; Hauptmeier, S.

    This paper applies structural vector autoregressions with time-varying parameters in order to investigate changes in the effects of government spending shocks in the euro area, and the driving forces of those changes. Our contribution is two-fold. First, we present evidence that the short-run impact

  12. The driving force of the Na+/Ca2+-exchanger during metabolic inhibition

    NARCIS (Netherlands)

    Baartscheer, Antonius; Schumacher, Cees A.; Coronel, Ruben; Fiolet, Jan W. T.

    2011-01-01

    Objective: Metabolic inhibition causes a decline in mechanical performance and, if prolonged, myocardial contracture and cell death. The decline in mechanical performance is mainly due to altered intracellular calcium handling, which is under control of the Na+/Ca2+-exchanger (NCX) The driving force

  13. Emission of greenhouse gases 1990-2010. Trends and driving forces

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-03-01

    Emissions of greenhouse gases in Norway from 1990-2010 - trends and driving forces, a report that presents emission trends in Norway with the analysis of the main drivers and trends, and a review and analysis of the effectiveness of implemented measures.(Author)

  14. A modified synthetic driving force method for molecular dynamics simulation of grain boundary migration

    International Nuclear Information System (INIS)

    Yang, Liang; Li, Saiyi

    2015-01-01

    The synthetic driving force (SDF) molecular dynamics method, which imposes crystalline orientation-dependent driving forces for grain boundary (GB) migration, has been considered deficient in many cases. In this work, we revealed the cause of the deficiency and proposed a modified method by introducing a new technique to distinguish atoms in grains and GB such that the driving forces can be imposed properly. This technique utilizes cross-reference order parameter (CROP) to characterize local lattice orientations in a bicrystal and introduces a CROP-based definition of interface region to minimize interference from thermal fluctuations in distinguishing atoms. A validation of the modified method was conducted by applying it to simulate the migration behavior of Ni 〈1 0 0〉 and Al 〈1 1 2〉 symmetrical tilt GBs, in comparison with the original method. The discrepancies between the migration velocities predicted by the two methods are found to be proportional to their differences in distinguishing atoms. For the Al 〈1 1 2〉 GBs, the modified method predicts a negative misorientation dependency for both the driving pressure threshold for initiating GB movement and the mobility, which agree with experimental findings and other molecular dynamics computations but contradict those predicted using the original method. Last, the modified method was applied to evaluate the mobility of Ni Σ5 〈1 0 0〉 symmetrical tilt GB under different driving pressure and temperature conditions. The results reveal a strong driving pressure dependency of the mobility at relatively low temperatures and suggest that the driving pressure should be as low as possible but large enough to trigger continuous migration.

  15. Current Reversal Due to Coupling Between Asymmetrical Driving Force and Ratchet Potential

    International Nuclear Information System (INIS)

    Ai Baoquan; Xie Huizhang; Liu Lianggang

    2006-01-01

    Transport of a Brownian particle moving in a periodic potential is investigated in the presence of an asymmetric unbiased external force. The asymmetry of the external force and the asymmetry of the potential are the two ways of inducing a net current. It is found that the competition of the spatial asymmetry of potential with the temporal asymmetry of the external force leads to the phenomena like current reversal. The competition between the two opposite driving factors is a necessary but not a sufficient condition for current reversals.

  16. Force analysis of the advanced neutron source control rod drive latch mechanism

    International Nuclear Information System (INIS)

    Damiano, B.

    1989-01-01

    The Advanced Neutron Source reactor (ANS), a proposed Department of Energy research reactor currently undergoing conceptual design at the Oak Ridge National Laboratory (ORNL), will generate a thermal neutron flux approximating 10 30 M -2 emdash S -1 . The compact core necessary to produce this flux provides little space for the shim safety control rods, which are located in the central annulus of the core. Without proper control rod drive design, the control rod drive magnets (which hold the control rod latch in a ready-to-scram position) may be unable to support the required load due to their restricted size. This paper describes the force analysis performed on the control rod latch mechanism to determine the fraction of control rod weight transferred to the drive magnet. This information will be useful during latch, control rod drive and magnet design. 5 refs., 12 figs

  17. Vehicle Dynamics Control of In-wheel Electric Motor Drive Vehicles Based on Averaging of Tire Force Usage

    Science.gov (United States)

    Masaki, Nobuo; Iwano, Haruo; Kamada, Takayoshi; Nagai, Masao

    For in-wheel electric motor drive vehicles, a new vehicle dynamics control which is based on the tire force usage rate is proposed. The new controller adopts non-linear optimal control could manage the interference between direct yaw-moment control and the tire force usage rate. The new control is considered total longitudinal and transverse tire force. Therefore the controller can prevent tire force saturation near tire force limit during cornering. Simulations and test runs by the custom made four wheel drive in-wheel motor electric vehicle show that higher driving stability performance compared to the performance of the same vehicle without control.

  18. Assembly constraints drive co-evolution among ribosomal constituents.

    Science.gov (United States)

    Mallik, Saurav; Akashi, Hiroshi; Kundu, Sudip

    2015-06-23

    Ribosome biogenesis, a central and essential cellular process, occurs through sequential association and mutual co-folding of protein-RNA constituents in a well-defined assembly pathway. Here, we construct a network of co-evolving nucleotide/amino acid residues within the ribosome and demonstrate that assembly constraints are strong predictors of co-evolutionary patterns. Predictors of co-evolution include a wide spectrum of structural reconstitution events, such as cooperativity phenomenon, protein-induced rRNA reconstitutions, molecular packing of different rRNA domains, protein-rRNA recognition, etc. A correlation between folding rate of small globular proteins and their topological features is known. We have introduced an analogous topological characteristic for co-evolutionary network of ribosome, which allows us to differentiate between rRNA regions subjected to rapid reconstitutions from those hindered by kinetic traps. Furthermore, co-evolutionary patterns provide a biological basis for deleterious mutation sites and further allow prediction of potential antibiotic targeting sites. Understanding assembly pathways of multicomponent macromolecules remains a key challenge in biophysics. Our study provides a 'proof of concept' that directly relates co-evolution to biophysical interactions during multicomponent assembly and suggests predictive power to identify candidates for critical functional interactions as well as for assembly-blocking antibiotic target sites. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

  19. Trophic specialization drives morphological evolution in sea snakes.

    Science.gov (United States)

    Sherratt, Emma; Rasmussen, Arne R; Sanders, Kate L

    2018-03-01

    Viviparous sea snakes are the most rapidly speciating reptiles known, yet the ecological factors underlying this radiation are poorly understood. Here, we reconstructed dated trees for 75% of sea snake species and quantified body shape (forebody relative to hindbody girth), maximum body length and trophic diversity to examine how dietary specialization has influenced morphological diversification in this rapid radiation. We show that sea snake body shape and size are strongly correlated with the proportion of burrowing prey in the diet. Specialist predators of burrowing eels have convergently evolved a 'microcephalic' morphotype with dramatically reduced forebody relative to hindbody girth and intermediate body length. By comparison, snakes that predominantly feed on burrowing gobies are generally short-bodied and small-headed, but there is no evidence of convergent evolution. The eel specialists also exhibit faster rates of size and shape evolution compared to all other sea snakes, including those that feed on gobies. Our results suggest that trophic specialization to particular burrowing prey (eels) has invoked strong selective pressures that manifest as predictable and rapid morphological changes. Further studies are needed to examine the genetic and developmental mechanisms underlying these dramatic morphological changes and assess their role in sea snake speciation.

  20. Driving-forces model on individual behavior in scenarios considering moving threat agents

    Science.gov (United States)

    Li, Shuying; Zhuang, Jun; Shen, Shifei; Wang, Jia

    2017-09-01

    The individual behavior model is a contributory factor to improve the accuracy of agent-based simulation in different scenarios. However, few studies have considered moving threat agents, which often occur in terrorist attacks caused by attackers with close-range weapons (e.g., sword, stick). At the same time, many existing behavior models lack validation from cases or experiments. This paper builds a new individual behavior model based on seven behavioral hypotheses. The driving-forces model is an extension of the classical social force model considering scenarios including moving threat agents. An experiment was conducted to validate the key components of the model. Then the model is compared with an advanced Elliptical Specification II social force model, by calculating the fitting errors between the simulated and experimental trajectories, and being applied to simulate a specific circumstance. Our results show that the driving-forces model reduced the fitting error by an average of 33.9% and the standard deviation by an average of 44.5%, which indicates the accuracy and stability of the model in the studied situation. The new driving-forces model could be used to simulate individual behavior when analyzing the risk of specific scenarios using agent-based simulation methods, such as risk analysis of close-range terrorist attacks in public places.

  1. Step-wise and punctuated genome evolution drive phenotype changes of tumor cells

    International Nuclear Information System (INIS)

    Stepanenko, Aleksei; Andreieva, Svitlana; Korets, Kateryna; Mykytenko, Dmytro; Huleyuk, Nataliya; Vassetzky, Yegor; Kavsan, Vadym

    2015-01-01

    genome context. Temozolomide treatment of 293-pcDNA3.1 cells intensified the stochastic punctuated genome changes and CNAs, and significantly reduced viability and CFE. In contrast, temozolomide treatment of HeLa-CHI3L1 cells promoted the step-wise genome changes, CNAs, and increased viability and CFE, which did not correlate with the ectopic CHI3L1 production. Thus, consistent coevolution of karyotypes and phenotypes was observed. CIN as a driving force of genome evolution significantly influences growth characteristics of tumor cells and should be always taken into consideration during the different experimental manipulations

  2. Step-wise and punctuated genome evolution drive phenotype changes of tumor cells

    Energy Technology Data Exchange (ETDEWEB)

    Stepanenko, Aleksei, E-mail: a.a.stepanenko@gmail.com [Department of Biosynthesis of Nucleic Acids, Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, Kyiv 03680 (Ukraine); Andreieva, Svitlana; Korets, Kateryna; Mykytenko, Dmytro [Department of Biosynthesis of Nucleic Acids, Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, Kyiv 03680 (Ukraine); Huleyuk, Nataliya [Institute of Hereditary Pathology, National Academy of Medical Sciences of Ukraine, Lviv 79008 (Ukraine); Vassetzky, Yegor [CNRS UMR8126, Université Paris-Sud 11, Institut de Cancérologie Gustave Roussy, Villejuif 94805 (France); Kavsan, Vadym [Department of Biosynthesis of Nucleic Acids, Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, Kyiv 03680 (Ukraine)

    2015-01-15

    genome context. Temozolomide treatment of 293-pcDNA3.1 cells intensified the stochastic punctuated genome changes and CNAs, and significantly reduced viability and CFE. In contrast, temozolomide treatment of HeLa-CHI3L1 cells promoted the step-wise genome changes, CNAs, and increased viability and CFE, which did not correlate with the ectopic CHI3L1 production. Thus, consistent coevolution of karyotypes and phenotypes was observed. CIN as a driving force of genome evolution significantly influences growth characteristics of tumor cells and should be always taken into consideration during the different experimental manipulations.

  3. A study on the fundamental mechanism and the evolutionary driving forces behind aerobic fermentation in yeast.

    Science.gov (United States)

    Hagman, Arne; Piškur, Jure

    2015-01-01

    Baker's yeast Saccharomyces cerevisiae rapidly converts sugars to ethanol and carbon dioxide at both anaerobic and aerobic conditions. The later phenomenon is called Crabtree effect and has been described in two forms, long-term and short-term effect. We have previously studied under fully controlled aerobic conditions forty yeast species for their central carbon metabolism and the presence of long-term Crabtree effect. We have also studied ten steady-state yeast cultures, pulsed them with glucose, and followed the central carbon metabolism and the appearance of ethanol at dynamic conditions. In this paper we analyzed those wet laboratory data to elucidate possible mechanisms that determine the fate of glucose in different yeast species that cover approximately 250 million years of evolutionary history. We determine overflow metabolism to be the fundamental mechanism behind both long- and short-term Crabtree effect, which originated approximately 125-150 million years ago in the Saccharomyces lineage. The "invention" of overflow metabolism was the first step in the evolution of aerobic fermentation in yeast. It provides a general strategy to increase energy production rates, which we show is positively correlated to growth. The "invention" of overflow has also simultaneously enabled rapid glucose consumption in yeast, which is a trait that could have been selected for, to "starve" competitors in nature. We also show that glucose repression of respiration is confined mainly among S. cerevisiae and closely related species that diverged after the whole genome duplication event, less than 100 million years ago. Thus, glucose repression of respiration was apparently "invented" as a second step to further increase overflow and ethanol production, to inhibit growth of other microbes. The driving force behind the initial evolutionary steps was most likely competition with other microbes to faster consume and convert sugar into biomass, in niches that were semi-anaerobic.

  4. A study on the fundamental mechanism and the evolutionary driving forces behind aerobic fermentation in yeast.

    Directory of Open Access Journals (Sweden)

    Arne Hagman

    Full Text Available Baker's yeast Saccharomyces cerevisiae rapidly converts sugars to ethanol and carbon dioxide at both anaerobic and aerobic conditions. The later phenomenon is called Crabtree effect and has been described in two forms, long-term and short-term effect. We have previously studied under fully controlled aerobic conditions forty yeast species for their central carbon metabolism and the presence of long-term Crabtree effect. We have also studied ten steady-state yeast cultures, pulsed them with glucose, and followed the central carbon metabolism and the appearance of ethanol at dynamic conditions. In this paper we analyzed those wet laboratory data to elucidate possible mechanisms that determine the fate of glucose in different yeast species that cover approximately 250 million years of evolutionary history. We determine overflow metabolism to be the fundamental mechanism behind both long- and short-term Crabtree effect, which originated approximately 125-150 million years ago in the Saccharomyces lineage. The "invention" of overflow metabolism was the first step in the evolution of aerobic fermentation in yeast. It provides a general strategy to increase energy production rates, which we show is positively correlated to growth. The "invention" of overflow has also simultaneously enabled rapid glucose consumption in yeast, which is a trait that could have been selected for, to "starve" competitors in nature. We also show that glucose repression of respiration is confined mainly among S. cerevisiae and closely related species that diverged after the whole genome duplication event, less than 100 million years ago. Thus, glucose repression of respiration was apparently "invented" as a second step to further increase overflow and ethanol production, to inhibit growth of other microbes. The driving force behind the initial evolutionary steps was most likely competition with other microbes to faster consume and convert sugar into biomass, in niches that

  5. Trends driving the hotel industry global evolution. Case of Romania

    Directory of Open Access Journals (Sweden)

    Codruţa-Adina BĂLTESCU

    2015-06-01

    Full Text Available The tourism field is well known for the dynamic of changes over recent years. We witness the continous growth of the number of tourists, the increase of consumers demands, the development of new markets and the changes determined by information technologies implementation and adaptations and innovations supported at the level of tourism business. Being a defining component in the tourism industry, the hotel field is individualized through specific evolutions and significant adjustments in relation to the general rate of changes and development trends recorded. In this framework, through this article, the author aims to assess which are the most relevant changes recorded in the Romanian hotel industry and the degree in which this specific activity field follow the trend of changes recorded at international level.

  6. A Study of the Effect of the Fringe Fields on the Electrostatic Force in Vertical Comb Drives

    Directory of Open Access Journals (Sweden)

    Else Gallagher

    2014-10-01

    Full Text Available The equation that describes the relationship between the applied voltage and the resulting electrostatic force within comb drives is often used to assist in choosing the dimensions for their design. This paper re-examines how some of these dimensions—particularly the cross-sectional dimensions of the comb teeth—affect this relationship in vertical comb drives. The electrostatic forces in several vertical comb drives fabricated for this study were measured and compared to predictions made with four different mathematical models in order to explore the amount of complexity required within a model to accurately predict the electrostatic forces in the comb drives.

  7. Agricultural land use change and associated driving forces over the past 180 years in two municipalities of the Brazilian Cerrado

    NARCIS (Netherlands)

    Arruda, de Murilo Rodrigues; Slingerland, Maja; Santos, José Zilton Lopes; Giller, Ken E.

    2018-01-01

    This paper aims to test the hypothesis that a single driving force from the local, national, or global level is capable of triggering land use changes, including large scale deforestation, within a historical context. To reach this goal we describe and explain the driving forces from the global to

  8. Position Control of Linear Synchronous Motor Drives with Exploitation of Forced Dynamics Control Principles

    Directory of Open Access Journals (Sweden)

    Jan Vittek

    2004-01-01

    Full Text Available Closed-loop position control of mechanisms directly driven by linear synchronous motors with permanent magnets is presented. The control strategy is based on forced dynamic control, which is a form of feedback linearisation, yielding a non-liner multivariable control law to obtain a prescribed linear speed dynamics together with the vector control condition of mutal orthogonality between the stator current and magnetic flux vectors (assuming perfect estimates of the plant parameters. Outer position control loop is closed via simple feedback with proportional gain. Simulations of the design control sysstem, including the drive with power electronic switching, predict the intended drive performance.

  9. The evolution of the placenta drives a shift in sexual selection in livebearing fish

    NARCIS (Netherlands)

    Pollux, B.J.A.; Meredith, R.W.; Springer, M.S.; Garland, T.; Reznick, D.N.

    2014-01-01

    The evolution of the placenta from a non-placental ancestor causes a shift of maternal investment from pre- to post-fertilization, creating a venue for parent–offspring conflicts during pregnancy1, 2, 3, 4. Theory predicts that the rise of these conflicts should drive a shift from a reliance on

  10. Analyzing the Long Term Cohesive Effect of Sector Specific Driving Forces.

    Directory of Open Access Journals (Sweden)

    Yonatan Berman

    Full Text Available Financial markets are partially composed of sectors dominated by external driving forces, such as commodity prices, infrastructure and other indices. We characterize the statistical properties of such sectors and present a novel model for the coupling of the stock prices and their dominating driving forces, inspired by mean reverting stochastic processes. Using the model we were able to explain the market sectors' long term behavior and estimate the coupling strength between stocks in financial markets and the sector specific driving forces. Notably, the analysis was successfully applied to the shipping market, in which the Baltic dry index (BDI, an assessment of the price of transporting the major raw materials by sea, influences the shipping financial market. We also present the analysis of other sectors-the gold mining market and the food production market, for which the model was also successfully applied. The model can serve as a general tool for characterizing the coupling between external forces and affected financial variables and therefore for estimating the risk in sectors and their vulnerability to external stress.

  11. The effect of drive frequency and set point amplitude on tapping forces in atomic force microscopy: simulation and experiment

    International Nuclear Information System (INIS)

    Legleiter, Justin

    2009-01-01

    In tapping mode atomic force microscopy (AFM), a sharp probe tip attached to an oscillating cantilever is allowed to intermittently strike a surface. By raster scanning the probe while monitoring the oscillation amplitude of the cantilever via a feedback loop, topographical maps of surfaces with nanoscale resolution can be acquired. While numerous studies have employed numerical simulations to elucidate the time-resolved tapping force between the probe tip and surface, until recent technique developments, specific read-outs from such models could not be experimentally verified. In this study, we explore, via numerical simulation, the impact of imaging parameters, i.e. set point ratio and drive frequency as a function of resonance, on time-varying tip-sample force interactions, which are directly compared to reconstructed tapping forces from real AFM experiments. As the AFM model contains a feedback loop allowing for the simulation of the entire scanning process, we further explore the impact that various tip-sample force have on the entire imaging process.

  12. Production bias: A proposed modification of the driving force for void swelling under cascade damage conditions

    International Nuclear Information System (INIS)

    Woo, C.H.; Garner, F.A.

    1991-11-01

    A new concept of point-defect production as the main driving force for void swelling under cascade damage conditions is proposed. This concept takes into account the recombination and formation of immobile clusters and loops of vacancies and interstitials in the cascade region. The life times of the clusters and loops due to desolution are strong functions of the temperature, as well as their vacancy and interstitial nature. The resulting biased production of free point defects from the internal sources is shown to be a strong driving force for void swelling. The characteristics of void swelling due to production bias are described and compared with experimental results. We conclude that the production bias concept provides a good description of void swelling under cascade damage conditions

  13. Production bias: A proposed modification of the driving force for void swelling under cascade damage conditions

    International Nuclear Information System (INIS)

    Woo, C.H.; Singh, B.N.; Garner, F.A.

    1992-01-01

    A new concept of point defect production as the main driving force for void swelling under cascade damage conditions is proposed. This concept takes into account the recombination and formation of immobile clusters and loops of vacancies and interstitials in the cascade region. The lifetimes of the clusters and loops due to desolution are strong functions of the temperature, as well as their vacancy and interstitial nature. The resulting biased production of free point defects from the internal sources is shown to be a strong driving force for void swelling. The characteristics of void swelling due to production bias are described and compared with experimental results. We conclude that the production bias concept provides a good description of void swelling under cascade damage conditions. (orig.)

  14. Testing thermal gradient driving force for grain boundary migration using molecular dynamics simulations

    International Nuclear Information System (INIS)

    Bai, Xian-Ming; Zhang, Yongfeng; Tonks, Michael R.

    2015-01-01

    Strong thermal gradients in low-thermal-conductivity ceramics may drive extended defects, such as grain boundaries and voids, to migrate in preferential directions. In this work, molecular dynamics simulations are conducted to study thermal gradient driven grain boundary migration and to verify a previously proposed thermal gradient driving force equation, using uranium dioxide as a model system. It is found that a thermal gradient drives grain boundaries to migrate up the gradient and the migration velocity increases under a constant gradient owing to the increase in mobility with temperature. Different grain boundaries migrate at very different rates due to their different intrinsic mobilities. The extracted mobilities from the thermal gradient driven simulations are compared with those calculated from two other well-established methods and good agreement between the three different methods is found, demonstrating that the theoretical equation of the thermal gradient driving force is valid, although a correction of one input parameter should be made. The discrepancy in the grain boundary mobilities between modeling and experiments is also discussed.

  15. Electronic structure and driving forces in {beta}-cyclodextrin: Diclofenac inclusion complexes

    Energy Technology Data Exchange (ETDEWEB)

    Bogdan, Diana [National Institute for Research and Development of Isotopic and Molecular Technologies, Donath street 71-103, 400293 Cluj-Napoca (Romania); Morari, C. [National Institute for Research and Development of Isotopic and Molecular Technologies, Donath street 71-103, 400293 Cluj-Napoca (Romania)]. E-mail: cristim@s3.itim-cj.ro

    2007-07-02

    We investigate the geometry and electronic structure for complexes of {beta}-cyclodextrin with diclofenac using DFT calculations. The effect of solvent is explicitly taken into account. This investigation allows us to draw meaningful conclusions upon the stability of the complex and the nature of the driving forces leading to the complexation process. In particular we emphasize the role of the water, by pointing out the changes in the solvent's electronic structure for different docking geometries.

  16. Electronic structure and driving forces in β-cyclodextrin: Diclofenac inclusion complexes

    International Nuclear Information System (INIS)

    Bogdan, Diana; Morari, C.

    2007-01-01

    We investigate the geometry and electronic structure for complexes of β-cyclodextrin with diclofenac using DFT calculations. The effect of solvent is explicitly taken into account. This investigation allows us to draw meaningful conclusions upon the stability of the complex and the nature of the driving forces leading to the complexation process. In particular we emphasize the role of the water, by pointing out the changes in the solvent's electronic structure for different docking geometries

  17. The world food situation: New driving forces and required actions [In Chinese

    OpenAIRE

    von Braun, Joachim

    2008-01-01

    "The world food situation is currently being rapidly redefined by new driving forces. Income growth, climate change, high energy prices, globalization, and urbanization are transforming food consumption, production, and markets. The influence of the private sector in the world food system, especially the leverage of food retailers, is also rapidly increasing. Changes in food availability, rising commodity prices, and new producer–consumer linkages have crucial implications for the livelihoods...

  18. Spatiotemporal Variation of Driving Forces for Settlement Expansion in Different Types of Counties

    Directory of Open Access Journals (Sweden)

    Guanglong Dong

    2015-12-01

    Full Text Available Understanding the process of settlement expansion and the spatiotemporal variation of driving forces is the foundation of rational and specific planning for sustainable development. However, little attention has been paid to the spatiotemporal differences of driving forces among different counties, especially when they are representatives of different development types. This study used Guanyun, Kunshan and Changshu as case studies, and binary logistic regression was employed. The results showed that the expansion rates of Kunshan and Changshu were 5.55 and 3.93 times higher than that of Guanyun. The combinations and relative importance of drivers varied with counties and periods. The change in the number of driving forces can be divided into three stages: increasing stage, decreasing stage, and stable stage. In the relatively developed counties, Kunshan and Changshu, the importance of population is decreased, while it remain an important factor in the less developed county, Guanyun. In addition, the effect of GDP stays the same in Kunshan while it becomes the most important factor in Changshu. The distance to the main road and the distance to town are increasingly important in Kunshan and Guanyun, and distance to town has been the only common factor in the last period, indicating the discrepancy is increased. The relative importance of distance to a lake in Kunshan and Changshu increased, reflecting the role of increasing tourism in accelerating settlement expansion.

  19. Magnetostatic torsional actuator with embedded nickel structures for the improvement of driving force and wobble motion

    International Nuclear Information System (INIS)

    Tang, Tsung-Lin; Fang, Weileun

    2011-01-01

    This study demonstrates the magnetostatic torsional actuator consisting in a Si–Ni compound frame to significantly improve the driving force. The present design has three merits: (1) it employs a Si mold to simultaneously electroplate/pattern thick Ni, and the Ni and Si structures respectively provide magnetostatic force and superior mechanical properties, (2) the embedded Ni structures not only increase the ferromagnetic material volume but also enhance magnetization strength to enlarge magnetostatic torque, (3) the Si–Ni compound structure, which is nearly symmetric about the torsional axis in the out-of-plane direction, can decrease the moment of inertia and also reduce the wobble motion. In applications, one-axis torsional actuator is implemented and characterized. The experiments show that the Si–Ni compound scanner has an optical scan angle θ optical = 90° with the input power 81 mW. The input power is decreased as compared with the existing scanner. Moreover, the out-of-plane wobble motion is only 44 nm at θ optical = 15°. Compared with the existing designs consisted of asymmetric structures in the out-of-plane direction, such as electroplated film and silicon rib, about the torsional axis, the equivalent eccentric force is reduced nearly two-fold. In short, the proposed design not only increases the driving force but also decreases the wobble motion

  20. A single evolutionary innovation drives the deep evolution of symbiotic N2-fixation in angiosperms

    Science.gov (United States)

    Werner, Gijsbert D. A.; Cornwell, William K.; Sprent, Janet I.; Kattge, Jens; Kiers, E. Toby

    2014-01-01

    Symbiotic associations occur in every habitat on earth, but we know very little about their evolutionary histories. Current models of trait evolution cannot adequately reconstruct the deep history of symbiotic innovation, because they assume homogenous evolutionary processes across millions of years. Here we use a recently developed, heterogeneous and quantitative phylogenetic framework to study the origin of the symbiosis between angiosperms and nitrogen-fixing (N2) bacterial symbionts housed in nodules. We compile the largest database of global nodulating plant species and reconstruct the symbiosis’ evolution. We identify a single, cryptic evolutionary innovation driving symbiotic N2-fixation evolution, followed by multiple gains and losses of the symbiosis, and the subsequent emergence of ‘stable fixers’ (clades extremely unlikely to lose the symbiosis). Originating over 100 MYA, this innovation suggests deep homology in symbiotic N2-fixation. Identifying cryptic innovations on the tree of life is key to understanding the evolution of complex traits, including symbiotic partnerships. PMID:24912610

  1. The evolution of Soviet forces, strategy, and command

    International Nuclear Information System (INIS)

    Ball, D.; Bethe, H.A.; Blair, B.G.; Bracken, P.; Carter, A.B.; Dickinson, H.; Garwin, R.L.; Holloway, D.; Kendall, H.W.

    1988-01-01

    This paper reports on the evolution of Soviet forces, strategy and command. Soviet leaders have repeatedly emphasized that it would be tantamount to suicide to start a nuclear war. Mutual deterrence, however, does not make nuclear was impossible. The danger remains that a large-scale nuclear was could start inadvertently in an intense crisis, or by escalation out of a conventional war, or as an unforeseen combination of these. For these reasons crisis management has become a central issue in the United States, but the standard Soviet response to this Western interest has been to say that what is needed is crisis avoidance, not recipes for brinkmanship masquerading under another name. There is much sense in this view. Nevertheless, this demeanor does not mean that the Soviet Union has given no thought to the danger that a crisis might lead to nuclear war, only that Soviet categories for thinking about such matters differ from those employed in the United States

  2. Mechanisms driving variability in the ocean forcing of Pine Island Glacier.

    Science.gov (United States)

    Webber, Benjamin G M; Heywood, Karen J; Stevens, David P; Dutrieux, Pierre; Abrahamsen, E Povl; Jenkins, Adrian; Jacobs, Stanley S; Ha, Ho Kyung; Lee, Sang Hoon; Kim, Tae Wan

    2017-02-17

    Pine Island Glacier (PIG) terminates in a rapidly melting ice shelf, and ocean circulation and temperature are implicated in the retreat and growing contribution to sea level rise of PIG and nearby glaciers. However, the variability of the ocean forcing of PIG has been poorly constrained due to a lack of multi-year observations. Here we show, using a unique record close to the Pine Island Ice Shelf (PIIS), that there is considerable oceanic variability at seasonal and interannual timescales, including a pronounced cold period from October 2011 to May 2013. This variability can be largely explained by two processes: cumulative ocean surface heat fluxes and sea ice formation close to PIIS; and interannual reversals in ocean currents and associated heat transport within Pine Island Bay, driven by a combination of local and remote forcing. Local atmospheric forcing therefore plays an important role in driving oceanic variability close to PIIS.

  3. Smaller beaks for colder winters: Thermoregulation drives beak size evolution in Australasian songbirds.

    Science.gov (United States)

    Friedman, Nicholas R; Harmáčková, Lenka; Economo, Evan P; Remeš, Vladimír

    2017-08-01

    Birds' beaks play a key role in foraging, and most research on their size and shape has focused on this function. Recent findings suggest that beaks may also be important for thermoregulation, and this may drive morphological evolution as predicted by Allen's rule. However, the role of thermoregulation in the evolution of beak size across species remains largely unexplored. In particular, it remains unclear whether the need for retaining heat in the winter or dissipating heat in the summer plays the greater role in selection for beak size. Comparative studies are needed to evaluate the relative importance of these functions in beak size evolution. We addressed this question in a clade of birds exhibiting wide variation in their climatic niche: the Australasian honeyeaters and allies (Meliphagoidea). Across 158 species, we compared species' climatic conditions extracted from their ranges to beak size measurements in a combined spatial-phylogenetic framework. We found that winter minimum temperature was positively correlated with beak size, while summer maximum temperature was not. This suggests that while diet and foraging behavior may drive evolutionary changes in beak shape, changes in beak size can also be explained by the beak's role in thermoregulation, and winter heat retention in particular. © 2017 The Author(s). Evolution © 2017 The Society for the Study of Evolution.

  4. Physical driving force of actomyosin motility based on the hydration effect.

    Science.gov (United States)

    Suzuki, Makoto; Mogami, George; Ohsugi, Hideyuki; Watanabe, Takahiro; Matubayasi, Nobuyuki

    2017-12-01

    We propose a driving force hypothesis based on previous thermodynamics, kinetics and structural data as well as additional experiments and calculations presented here on water-related phenomena in the actomyosin systems. Although Szent-Györgyi pointed out the importance of water in muscle contraction in 1951, few studies have focused on the water science of muscle because of the difficulty of analyzing hydration properties of the muscle proteins, actin, and myosin. The thermodynamics and energetics of muscle contraction are linked to the water-mediated regulation of protein-ligand and protein-protein interactions along with structural changes in protein molecules. In this study, we assume the following two points: (1) the periodic electric field distribution along an actin filament (F-actin) is unidirectionally modified upon binding of myosin subfragment 1 (M or myosin S1) with ADP and inorganic phosphate Pi (M.ADP.Pi complex) and (2) the solvation free energy of myosin S1 depends on the external electric field strength and the solvation free energy of myosin S1 in close proximity to F-actin can become the potential force to drive myosin S1 along F-actin. The first assumption is supported by integration of experimental reports. The second assumption is supported by model calculations utilizing molecular dynamics (MD) simulation to determine solvation free energies of a small organic molecule and two small proteins. MD simulations utilize the energy representation method (ER) and the roughly proportional relationship between the solvation free energy and the solvent-accessible surface area (SASA) of the protein. The estimated driving force acting on myosin S1 is as high as several piconewtons (pN), which is consistent with the experimentally observed force. © 2017 Wiley Periodicals, Inc.

  5. ANALYTICAL SYNTHESIS OF FORCED PULSE ELECTRONIC DRIVE CONTROL OF A TRACKING SYSTEM

    Directory of Open Access Journals (Sweden)

    A. S. Abufanas

    2017-01-01

    Full Text Available The problem of analytical synthesis of a control signal by a linear dynamical system is considered. As an optimization criterion, it is proposed to consider the transition time of the system from the initial state to a given final state. This type of control is called forced, providing the maximum system speed. The principle of solving this problem is considered on the basis of application of uncertain Lagrange multipliers and the Pontryagin maximum principle. Expressions are obtained for the matrix of transitions of the system and the control signal in a vector form.As an example, the electric drive described by the widespread second-order mathematical model is considered to evaluate the efficiency of the proposed method. Qualitative illustrations of the operability of the proposed approach, obtained by modeling in the Mathcad environment, and quantitative characteristics of the change in the input and output signals of the hypothetical control system are presented. It is shown that the use of forced control does not lead to the output of variables characterizing the state of the system, beyond the limits of admissible values.The use of forced control makes it possible to synthesize the control law in the form of a sequence of rectangular pulses of constant amplitude determined by the power source, variable duty cycle and polarity. This approach can be used for the control of DC-type DC motors used in various tracking systems used on unmanned aerial vehicles. Key words: forced control, target function, electric drive, pulse train. The use of forced control makes it possible to synthesize the control law in the form of a sequence of rectangular pulses of constant amplitude determined by the power source, variable duty cycle and polarity. This approach can be used for the control of DC-type DC motors used in various tracking systems used on unmanned aerial vehicles.

  6. Finite Element Analysis of the Vertical Levitation Force in an Electrostatic MEMS Comb Drive Actuator

    International Nuclear Information System (INIS)

    Wooldridge, J; Blackburn, J; Muniz-Piniella, A; Stewart, M; Shean, T A V; Weaver, P M; Cain, M G

    2013-01-01

    A vertical levitation electrostatic comb drive actuator was manufactured for the purpose of measuring piezoelectric coefficients in small-scale materials and devices. Previous modelling work on comb drive levitation has focussed on control of the levitation in standard poly-silicon devices in order to minimize effects on lateral modes of operation required for the accelerometer and gyroscope applications. The actuator developed in this study was manufactured using a 20 μm electroplated Ni process with a 25 μm trench created beneath the released structure through chemical wet etching. A finite element analysis using ZINC was used to model electrostatic potential around a cross section of one static and one movable electrode, from which the net levitation force per unit electrode was calculated. The model was first verified using the electrode geometry from previously studied systems, and then used to study the variation of force as a function of decreasing substrate-electrode distance. With the top electrode surfaces collinear the calculated force density is 0.00651 ε 0 V 2 M μm −1 , equivalent to a total force for the device of 36.4 μN at an applied voltage of V M =100 V, just 16% larger than the observed value. The measured increase in force with distance was smaller than predicted with the FEA, due to the geometry of the device in which the electrodes at the anchored ends of the supporting spring structure displace by a smaller amount than those at the centre

  7. Trends and driving forces of ecological training and education in the context of ecological education environment of the technical university

    OpenAIRE

    Danilenkova V. A.

    2017-01-01

    common patterns of ecological training and education in the technical university are analyzed in this article, their descriptions are defined. Driving forces of ecological training and education in the context of ecological education environment are discovered and proved. According to conducted research the author makes a proposition to point out at ecological risks as driving forces, searching for which improves the efficiency and effectiveness of ecological education environment. The resear...

  8. Scrambling Eggs: Meiotic Drive and the Evolution of Female Recombination Rates

    Science.gov (United States)

    Brandvain, Yaniv; Coop, Graham

    2012-01-01

    Theories to explain the prevalence of sex and recombination have long been a central theme of evolutionary biology. Yet despite decades of attention dedicated to the evolution of sex and recombination, the widespread pattern of sex differences in the recombination rate is not well understood and has received relatively little theoretical attention. Here, we argue that female meiotic drivers—alleles that increase in frequency by exploiting the asymmetric cell division of oogenesis—present a potent selective pressure favoring the modification of the female recombination rate. Because recombination plays a central role in shaping patterns of variation within and among dyads, modifiers of the female recombination rate can function as potent suppressors or enhancers of female meiotic drive. We show that when female recombination modifiers are unlinked to female drivers, recombination modifiers that suppress harmful female drive can spread. By contrast, a recombination modifier tightly linked to a driver can increase in frequency by enhancing female drive. Our results predict that rapidly evolving female recombination rates, particularly around centromeres, should be a common outcome of meiotic drive. We discuss how selection to modify the efficacy of meiotic drive may contribute to commonly observed patterns of sex differences in recombination. PMID:22143919

  9. Force Sensitive Handles and Capacitive Touch Sensor for Driving a Flexible Haptic-Based Immersive System

    OpenAIRE

    Covarrubias, Mario; Bordegoni, Monica; Cugini, Umberto

    2013-01-01

    In this article, we present an approach that uses both two force sensitive handles (FSH) and a flexible capacitive touch sensor (FCTS) to drive a haptic-based immersive system. The immersive system has been developed as part of a multimodal interface for product design. The haptic interface consists of a strip that can be used by product designers to evaluate the quality of a 3D virtual shape by using touch, vision and hearing and, also, to interactively change the shape of the virtual object...

  10. Remote sensing monitoring and driving force analysis to forest and greenbelt in Zhuhai

    Science.gov (United States)

    Yuliang Qiao, Pro.

    As an important city in the southern part of Chu Chiang Delta, Zhuhai is one of the four special economic zones which are opening up to the outside at the earliest in China. With pure and fresh air and trees shading the street, Zhuhai is a famous beach port city which is near the mountain and by the sea. On the basis of Garden City, the government of Zhuhai decides to build National Forest City in 2011, which firstly should understand the situation of greenbelt in Zhuhai in short term. Traditional methods of greenbelt investigation adopt the combination of field surveying and statistics, whose efficiency is low and results are not much objective because of artificial influence. With the adventure of the information technology such as remote sensing to earth observation, especially the launch of many remote sensing satellites with high resolution for the past few years, kinds of urban greenbelt information extraction can be carried out by using remote sensing technology; and dynamic monitoring to spatial pattern evolvement of forest and greenbelt in Zhuhai can be achieved by the combination of remote sensing and GIS technology. Taking Landsat5 TM data in 1995, Landsat7 ETM+ data in 2002, CCD and HR data of CBERS-02B in 2009 as main information source, this research firstly makes remote sensing monitoring to dynamic change of forest and greenbelt in Zhuhai by using the combination of vegetation coverage index and three different information extraction methods, then does a driving force analysis to the dynamic change results in 3 months. The results show: the forest area in Zhuhai shows decreasing tendency from 1995 to 2002, increasing tendency from 2002 to 2009; overall, the forest area show a small diminution tendency from 1995 to 2009. Through the comparison to natural and artificial driving force, the artificial driving force is the leading factor to the change of forest and greenbelt in Zhuhai. The research results provide a timely and reliable scientific basis

  11. Selective sweeps of mitochondrial DNA can drive the evolution of uniparental inheritance.

    Science.gov (United States)

    Christie, Joshua R; Beekman, Madeleine

    2017-08-01

    Although the uniparental (or maternal) inheritance of mitochondrial DNA (mtDNA) is widespread, the reasons for its evolution remain unclear. Two main hypotheses have been proposed: selection against individuals containing different mtDNAs (heteroplasmy) and selection against "selfish" mtDNA mutations. Recently, uniparental inheritance was shown to promote adaptive evolution in mtDNA, potentially providing a third hypothesis for its evolution. Here, we explore this hypothesis theoretically and ask if the accumulation of beneficial mutations provides a sufficient fitness advantage for uniparental inheritance to invade a population in which mtDNA is inherited biparentally. In a deterministic model, uniparental inheritance increases in frequency but cannot replace biparental inheritance if only a single beneficial mtDNA mutation sweeps through the population. When we allow successive selective sweeps of mtDNA, however, uniparental inheritance can replace biparental inheritance. Using a stochastic model, we show that a combination of selection and drift facilitates the fixation of uniparental inheritance (compared to a neutral trait) when there is only a single selective mtDNA sweep. When we consider multiple mtDNA sweeps in a stochastic model, uniparental inheritance becomes even more likely to replace biparental inheritance. Our findings thus suggest that selective sweeps of beneficial mtDNA haplotypes can drive the evolution of uniparental inheritance. © 2017 The Author(s). Evolution © 2017 The Society for the Study of Evolution.

  12. Driving forces behind the Chinese public's demand for improved environmental safety.

    Science.gov (United States)

    Wen, Ting; Wang, Jigan; Ma, Zongwei; Bi, Jun

    2017-12-15

    Over the past decades, the public demand for improved environmental safety keeps increasing in China. This study aims to assess the driving forces behind the increasing public demand for improved environmental safety using a provincial and multi-year (1995, 2000, 2005, 2010, and 2014) panel data and the Stochastic Impacts by Regression on Population, Affluence, and Technology (STIRPAT) model. The potential driving forces investigated included population size, income levels, degrees of urbanization, and educational levels. Results show that population size and educational level are positively (Pdemand for improved environmental safety. No significant impact on demand was found due to the degree of urbanization. For the impact due to income level, an inverted U-shaped curve effect with the turning point of ~140,000 CNY GDP per capita is indicated. Since per capita GDP of 2015 in China was approximately 50,000 CNY and far from the turning point, the public demand for improved environmental safety will continue rising in the near future. To meet the increasing public demand for improved environmental safety, proactive and risk prevention based environmental management systems coupled with effective environmental risk communication should be established. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Negotiating EU CO2/energy taxation. Political economic driving forces and barriers

    International Nuclear Information System (INIS)

    Klok, Jacob

    2001-11-01

    The primary objective of this project is to identify the main political economic driving forces behind and barriers against the creation of an EU agreement on CO 2 /energy taxation. The analysis is based on a theoretical framework for understanding European integration and on detailed historical investigations into a process of EU negotiations concerning CO 2 /energy taxation that took place from the 1980s to 1994. Following the historical analysis of political economic driving forces and barriers, some overall perspectives on possible future developments within the field of EU CO 2 /energy taxation are finally advanced. The secondary objective of the project is to consider the possible effects on the EU negotiation process of Danish efforts to push the CO 2 /energy tax proposal from the late 1980s to 994. This analysis is based on the preceding historical analysis of the EU negotiation process, as well as further investigations into the national Danish development within the field of CO 2 /energy taxation, including accounts of Denmark's particular relations with the EU during the period in question. Finally, based on the likely future developments in the field EU CO 2 /energy taxation. Denmark's strategic opportunities are outlined. (BA)

  14. Driving forces behind the construction of an eco-compensation mechanism for wetlands in China

    Science.gov (United States)

    Wang, Changhai

    2016-09-01

    This research revealed important driving forces behind the construction of an eco-compensation mechanism for wetlands (DFEMW) in China. Using China's provincial panel data from 1978 to 2008, a fixed-effects model was used to analyze the impacts of agricultural production systems on wetlands. We identified three DFEMW as follows: the change of wetland resources and protection measures in China; declaration and implementation of the provincial Wetland Protection Ordinance; and wetland degradation by agricultural production systems, which necessitated the establishment of a wetland eco-compensation mechanism. In addition to the DFEMW, a significant positive correlation between wetland area and both rural population and gross agricultural production was identified, in addition to a negative correlation with chemical fertilizer usage, reservoir storage capacity, and irrigation area. The underlying reasons for the serious degradation and inadequate protection of wetlands were market failure and government failure; these were the driving forces behind the need to establish a wetland eco-compensation mechanism. From a governmental perspective, it has been difficult to rectify market failures in resource distribution and thus to prevent wetland degradation. Factors include conflicts of interest, lack of investment, effective special laws, a simple means to protect wetlands, and a multidisciplinary management system. Therefore, the key factor is the coordination of interest relationships between those who utilize wetlands and those who seek to minimize wetland degradation and effectively protect wetlands.

  15. Driving forces and barriers for environmental technology development; Drivkrefter og barrierer for utvikling av miljoeteknologi

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    Driving forces and barriers behind development and usage of environmental technology is discussed, and also whether there are certain characteristics related to environmental innovations compared to other innovations in general. The development of environmental technology is in principle dominated by the same drivers and barriers as any other technology, but the order and strength of the various factors may be different. This examination as well as other empirical studies shows that regulations play a greater part for environmental technology than 'pure market forces'. To many participants it is important to be one step ahead of the regulations, i.e. the expected regulations are equally important as the factual ones in driving the technology development. Players in the business community express that it is important that the authorities cooperate with them when introducing new regulations. This will increase acceptance for the regulations and facilitate the necessary adjustments. The most important barrier in the development and use of the technologies studied is probably the lack of demand.

  16. Temperature and Evolutionary Novelty as Forces behind the Evolution of General Intelligence

    Science.gov (United States)

    Kanazawa, Satoshi

    2008-01-01

    How did human intelligence evolve to be so high? Lynn [Lynn, R. (1991). The evolution of race differences in intelligence. Mankind Quarterly, 32, 99-173] and Rushton [Rushton, J.P. (1995). Race, evolution, and behavior: A life history perspective. New Brunswick: Transaction] suggest that the main forces behind the evolution of human intelligence…

  17. Human health and the water environment: using the DPSEEA framework to identify the driving forces of disease.

    Science.gov (United States)

    Gentry-Shields, Jennifer; Bartram, Jamie

    2014-01-15

    There is a growing awareness of global forces that threaten human health via the water environment. A better understanding of the dynamic between human health and the water environment would enable prediction of the significant driving forces and effective strategies for coping with or preventing them. This report details the use of the Driving Force-Pressure-State-Exposure-Effect-Action (DPSEEA) framework to explore the linkage between water-related diseases and their significant driving forces. The DPSEEA frameworks indicate that a select group of driving forces, including population growth, agriculture, infrastructure (dams and irrigation), and climate change, is at the root cause of key global disease burdens. Construction of the DPSEEA frameworks also allows for the evaluation of public health interventions. Sanitation was found to be a widely applicable and effective intervention, targeting the driver/pressure linkage of most of the water-related diseases examined. Ultimately, the DPSEEA frameworks offer a platform for constituents in both the health and environmental fields to collaborate and commit to a common goal targeting the same driving forces. © 2013.

  18. Driving forces for adsorption of amphiphilic peptides to the air-water interface.

    Science.gov (United States)

    Engin, Ozge; Villa, Alessandra; Sayar, Mehmet; Hess, Berk

    2010-09-02

    We have studied the partitioning of amphiphilic peptides at the air-water interface. The free energy of adsorption from bulk to interface was calculated by determining the potential of mean force via atomistic molecular dynamics simulations. To this end a method is introduced to restrain or constrain the center of mass of a group of molecules in a periodic system. The model amphiphilic peptides are composed of alternating valine and asparagine residues. The decomposition of the free energy difference between the bulk and interface is studied for different peptide block lengths. Our analysis revealed that for short amphiphilic peptides the surface driving force dominantly stems from the dehydration of hydrophobic side chains. The only opposing force is associated with the loss of orientational freedom of the peptide at the interface. For the peptides studied, the free energy difference scales linearly with the size of the molecule, since the peptides mainly adopt extended conformations both in bulk and at the interface. The free energy difference depends strongly on the water model, which can be rationalized through the hydration thermodynamics of hydrophobic solutes. Finally, we measured the reduction of the surface tension associated with complete coverage of the interface with peptides.

  19. Driving forces shaping advanced reactor designs: Near-term and long-term prospects

    International Nuclear Information System (INIS)

    Sholly, S.C.

    1990-01-01

    This paper explores the forces which have driven and which in the opinion of the author should be driving advanced reactor development programs. Four general driving forces are identified: cost, safety, environmental concerns, and non-proliferation concerns. It is suggested that the primary driving forces should be cost and safety concerns. It is suggested that advanced reactors need to demonstrate the following characteristics: (a) A design which explicitly accounts for severe accidents, including severe external events (not necessarily limited to contemporary design basis events) and which results in a frequency of severe core damage substantially lower than in current plants. The goal for the frequency of severe core damage should reflect a reasonable assurance that a severe core damage accident will not occur during the operating lifetime of a fleet' of such plants. (b) A design which explicitly accounts for severe accidents in terms of accident mitigation, resulting in a very low conditional likelihood of a substantial fission product release given a severe accident. (c) A design which utilizes near-passive and passive concepts (whose safety and reliability are demonstrable by experiment and/or full-scale test) for both accident prevention and accident mitigation to the maximum extent feasible. (d) A design which allows f a suitably long time between refueling outages, with a balance struck between refueling outage duration and refueling outage frequency so as to maximize availability and capacity factor. (e) A design which emphasizes modular construction and exceptional quality control. (f) A design which de emphasizes the importance of maintenance and human reliability more generally to assure that safety functions are performed with acceptable reliability, and to assure that passive safety characteristics are not compromised by design, manufacturing, or installation defects. It is further suggested that key factors in gaining public acceptance are the early

  20. Driving forces shaping advanced reactor designs: Near-term and long-term prospects

    Energy Technology Data Exchange (ETDEWEB)

    Sholly, S C [MHB Technical Associates, San Jose, CA (United States)

    1990-07-01

    This paper explores the forces which have driven and which in the opinion of the author should be driving advanced reactor development programs. Four general driving forces are identified: cost, safety, environmental concerns, and non-proliferation concerns. It is suggested that the primary driving forces should be cost and safety concerns. It is suggested that advanced reactors need to demonstrate the following characteristics: (a) A design which explicitly accounts for severe accidents, including severe external events (not necessarily limited to contemporary design basis events) and which results in a frequency of severe core damage substantially lower than in current plants. The goal for the frequency of severe core damage should reflect a reasonable assurance that a severe core damage accident will not occur during the operating lifetime of a fleet' of such plants. (b) A design which explicitly accounts for severe accidents in terms of accident mitigation, resulting in a very low conditional likelihood of a substantial fission product release given a severe accident. (c) A design which utilizes near-passive and passive concepts (whose safety and reliability are demonstrable by experiment and/or full-scale test) for both accident prevention and accident mitigation to the maximum extent feasible. (d) A design which allows f a suitably long time between refueling outages, with a balance struck between refueling outage duration and refueling outage frequency so as to maximize availability and capacity factor. (e) A design which emphasizes modular construction and exceptional quality control. (f) A design which de emphasizes the importance of maintenance and human reliability more generally to assure that safety functions are performed with acceptable reliability, and to assure that passive safety characteristics are not compromised by design, manufacturing, or installation defects. It is further suggested that key factors in gaining public acceptance are the early

  1. Parasitism drives host genome evolution: Insights from the Pasteuria ramosa-Daphnia magna system.

    Science.gov (United States)

    Bourgeois, Yann; Roulin, Anne C; Müller, Kristina; Ebert, Dieter

    2017-04-01

    Because parasitism is thought to play a major role in shaping host genomes, it has been predicted that genomic regions associated with resistance to parasites should stand out in genome scans, revealing signals of selection above the genomic background. To test whether parasitism is indeed such a major factor in host evolution and to better understand host-parasite interaction at the molecular level, we studied genome-wide polymorphisms in 97 genotypes of the planktonic crustacean Daphnia magna originating from three localities across Europe. Daphnia magna is known to coevolve with the bacterial pathogen Pasteuria ramosa for which host genotypes (clonal lines) are either resistant or susceptible. Using association mapping, we identified two genomic regions involved in resistance to P. ramosa, one of which was already known from a previous QTL analysis. We then performed a naïve genome scan to test for signatures of positive selection and found that the two regions identified with the association mapping further stood out as outliers. Several other regions with evidence for selection were also found, but no link between these regions and phenotypic variation could be established. Our results are consistent with the hypothesis that parasitism is driving host genome evolution. © 2017 The Author(s). Evolution © 2017 The Society for the Study of Evolution.

  2. How sexual selection can drive the evolution of costly sperm ornamentation

    Science.gov (United States)

    Lüpold, Stefan; Manier, Mollie K.; Puniamoorthy, Nalini; Schoff, Christopher; Starmer, William T.; Luepold, Shannon H. Buckley; Belote, John M.; Pitnick, Scott

    2016-05-01

    Post-copulatory sexual selection (PSS), fuelled by female promiscuity, is credited with the rapid evolution of sperm quality traits across diverse taxa. Yet, our understanding of the adaptive significance of sperm ornaments and the cryptic female preferences driving their evolution is extremely limited. Here we review the evolutionary allometry of exaggerated sexual traits (for example, antlers, horns, tail feathers, mandibles and dewlaps), show that the giant sperm of some Drosophila species are possibly the most extreme ornaments in all of nature and demonstrate how their existence challenges theories explaining the intensity of sexual selection, mating-system evolution and the fundamental nature of sex differences. We also combine quantitative genetic analyses of interacting sex-specific traits in D. melanogaster with comparative analyses of the condition dependence of male and female reproductive potential across species with varying ornament size to reveal complex dynamics that may underlie sperm-length evolution. Our results suggest that producing few gigantic sperm evolved by (1) Fisherian runaway selection mediated by genetic correlations between sperm length, the female preference for long sperm and female mating frequency, and (2) longer sperm increasing the indirect benefits to females. Our results also suggest that the developmental integration of sperm quality and quantity renders post-copulatory sexual selection on ejaculates unlikely to treat male-male competition and female choice as discrete processes.

  3. Robust 2-Qubit Gates in a Linear Ion Crystal Using a Frequency-Modulated Driving Force

    Science.gov (United States)

    Leung, Pak Hong; Landsman, Kevin A.; Figgatt, Caroline; Linke, Norbert M.; Monroe, Christopher; Brown, Kenneth R.

    2018-01-01

    In an ion trap quantum computer, collective motional modes are used to entangle two or more qubits in order to execute multiqubit logical gates. Any residual entanglement between the internal and motional states of the ions results in loss of fidelity, especially when there are many spectator ions in the crystal. We propose using a frequency-modulated driving force to minimize such errors. In simulation, we obtained an optimized frequency-modulated 2-qubit gate that can suppress errors to less than 0.01% and is robust against frequency drifts over ±1 kHz . Experimentally, we have obtained a 2-qubit gate fidelity of 98.3(4)%, a state-of-the-art result for 2-qubit gates with five ions.

  4. On the driving force for crack growth during thermal actuation of shape memory alloys

    Science.gov (United States)

    Baxevanis, T.; Parrinello, A. F.; Lagoudas, D. C.

    2016-04-01

    The effect of thermomechanically induced phase transformation on the driving force for crack growth in polycrystalline shape memory alloys is analyzed in an infinite center-cracked plate subjected to a thermal actuation cycle under mechanical load in plain strain. Finite element calculations are carried out to determine the mechanical fields near the static crack and the crack-tip energy release rate using the virtual crack closure technique. A substantial increase of the energy release rate - an order of magnitude for some material systems - is observed during the thermal cycle due to the stress redistribution induced by large scale phase transformation. Thus, phase transformation occurring due to thermal variations under mechanical load may result in crack growth if the crack-tip energy release rate reaches a material specific critical value.

  5. Design and Synthesis of Distillation Systems using a Driving Force Based Approach

    DEFF Research Database (Denmark)

    Bek-Pedersen, Erik; Gani, Rafiqul

    2004-01-01

    A new integrated framework for synthesis, design and operation of distillation-based separation schemes is presented here. This framework is based on the driving force approach, which provides a measure of the differences in chemical/physical properties between two co-existing phases...... in a separation unit. A set of algorithms has been developed within this framework for design of simple as well as complex distillation columns, for the sequencing of distillation trains, for the determination of appropriate conditions of operation and for retrofit of distillation columns. The main feature of all...... these algorithms is that they provide a simple "visual" method to obtain near-optimal solutions in terms of energy consumption without rigorous simulation and/or optimisation. Several illustrative examples highlighting the application of the integrated approach are also presented. (C) 2003 Published by Elsevier B.V....

  6. Driving forces: Motor vehicle trends and their implications for global warming, energy strategies, and transportation planning

    International Nuclear Information System (INIS)

    MacKenzie, J.J.; Walsh, M.P.

    1990-01-01

    Cars, trucks, and other vehicles have long been linked to smog and other urban pollution, but the part they play in the larger complex of atmospheric and energy ills that we now face is often overlooked. In Driving Forces: Motor Vehicle Trends and Their Implications for Global Warming, Energy Strategies, and Transportation Planning, James J. MacKenzie, senior associate in World Resources Institute's Program in Climate, Energy, and Pollution, and Michael P. Walsh, an international consultant on transportation and environmental issues, fill in this knowledge gap with new data and analyses. They spell out four policy shifts that can help hold the line on global warming: improve new-vehicle efficiency; make transportation more efficient; cut other greenhouse gas emissions; create the green car of the future. The report focuses especially on the US, which pioneered the automotive revolution and leads the world in oil imports and emissions

  7. Computational simulations of direct contact condensation as the driving force for water hammer

    International Nuclear Information System (INIS)

    Ceuca, Sabin-Cristian

    2015-01-01

    An analysis, based on Computer Simulations of the Direct Contact Condensation as the Driving Force for the Condensation Induced Water Hammer phenomenon is performed within this thesis. The goal of the work is to develop a mechanistic HTC model, with predictive capabilities for the simulation of horizontal or nearly horizontal two-phase ows with complex patterns including the e ect of interfacial heat and mass transfer. The newly developed HTC model was implemented into the system code ATHLET and into the CFD tools ANSYS CFX and OpenFOAM. Validation calculations have been performed for horizontal or nearly horizontal ows, where simulation results have been compared against the local measurement data such as void and temperature or area averaged data delivered by a wire mesh sensor.

  8. Greatest Happiness Principle in a Complex System: Maximisation versus Driving Force

    Directory of Open Access Journals (Sweden)

    Katalin Martinás

    2012-06-01

    Full Text Available From philosophical point of view, micro-founded economic theories depart from the principle of the pursuit of the greatest happiness. From mathematical point of view, micro-founded economic theories depart from the utility maximisation program. Though economists are aware of the serious limitations of the equilibrium analysis, they remain in that framework. We show that the maximisation principle, which implies the equilibrium hypothesis, is responsible for this impasse. We formalise the pursuit of the greatest happiness principle by the help of the driving force postulate: the volumes of activities depend on the expected wealth increase. In that case we can get rid of the equilibrium hypothesis and have new insights into economic theory. For example, in what extent standard economic results depend on the equilibrium hypothesis?

  9. Output Force Enhancement of Scratch Drive Actuator in Low-Voltage Region by Using Flexible Joint

    Directory of Open Access Journals (Sweden)

    Shawn CHEN

    2010-04-01

    Full Text Available Here a low-voltage scratch drive actuator (LVSDA is proposed by incorporating flexible joint into the conventional SDA to improve performance in low-voltage region. Experimental results show that, at the same total plate length of 80 mm and width of 65 mm, the proposed LVSDA can be actuated as low as 40 V, much lower than 80 V, the minimum required input voltage of the conventional SDA. From finite element analysis by CosmosWorks, yielding effect is found to be a critical factor. Before yielding, LVSDA can provide better performance than SDA at the same input voltage. However, the yielding stress in flexible joint would limit the achievable maximum output force in high-voltage region. By varying joint length, width, or location, LVSDA is shown to be operated in low-voltage region where the conventional SDA can not be operated, and can still provide comparable performance as SDA in high-voltage region.

  10. An analysis of the driving forces of CO2 emissions embodied in Japan-China trade

    International Nuclear Information System (INIS)

    Dong Yanli; Ishikawa, Masanobu; Liu Xianbing; Wang Can

    2010-01-01

    By using the latest China-Japan input-output data sets and the index decomposition analysis (IDA) approach, this article analyzes the driving forces of CO 2 emissions embodied in trade between the two countries during 1990-2000. We found that the growth of trade volume had a large influence on the increase of CO 2 emissions embodiments in bilateral trade. The dramatic decline in carbon intensity of the Chinese economy is a primary cause in offsetting CO 2 emissions exported from China to Japan over 1995-2000. We argue that a better understanding of the factors affecting CO 2 emissions embodied in international trade will assist in seeking more effective climate policies with wider participation in the post-Kyoto regime.

  11. Computational simulations of direct contact condensation as the driving force for water hammer

    Energy Technology Data Exchange (ETDEWEB)

    Ceuca, Sabin-Cristian

    2015-04-27

    An analysis, based on Computer Simulations of the Direct Contact Condensation as the Driving Force for the Condensation Induced Water Hammer phenomenon is performed within this thesis. The goal of the work is to develop a mechanistic HTC model, with predictive capabilities for the simulation of horizontal or nearly horizontal two-phase ows with complex patterns including the e ect of interfacial heat and mass transfer. The newly developed HTC model was implemented into the system code ATHLET and into the CFD tools ANSYS CFX and OpenFOAM. Validation calculations have been performed for horizontal or nearly horizontal ows, where simulation results have been compared against the local measurement data such as void and temperature or area averaged data delivered by a wire mesh sensor.

  12. Changing and Differentiated Urban Landscape in China: Spatiotemporal Patterns and Driving Forces.

    Science.gov (United States)

    Fang, Chuanglin; Li, Guangdong; Wang, Shaojian

    2016-03-01

    Urban landscape spatiotemporal change patterns and their driving mechanisms in China are poorly understood at the national level. Here we used remote sensing data, landscape metrics, and a spatial econometric model to characterize the spatiotemporal patterns of urban landscape change and investigate its driving forces in China between 1990 and 2005. The results showed that the urban landscape pattern has experienced drastic changes over the past 15 years. Total urban area has expanded approximately 1.61 times, with a 2.98% annual urban-growth rate. Compared to previous single-city studies, although urban areas are expanding rapidly, the overall fragmentation of the urban landscape is decreasing and is more irregular and complex at the national level. We also found a stair-stepping, urban-landscape changing pattern among eastern, central, and western counties. In addition, administrative level, urban size, and hierarchy have effects on the urban landscape pattern. We also found that a combination of landscape metrics can be used to supplement our understanding of the pattern of urbanization. The changes in these metrics are correlated with geographical indicators, socioeconomic factors, infrastructure variables, administrative level factors, policy factors, and historical factors. Our results indicate that the top priority should be strengthening the management of urban planning. A compact and congregate urban landscape may be a good choice of pattern for urban development in China.

  13. Stabilization of car-caravan combination using independent steer and drive/or brake forces distribution

    Directory of Open Access Journals (Sweden)

    Ossama Mokhiamar

    2015-09-01

    Full Text Available Once a combined vehicle becomes unstable, it is very difficult for a driver to stabilize it especially under severe driving conditions, such as turning with braking. This is mainly due to the effect of the towed vehicle on the towing vehicle through the hitch jackknifing. This effect makes the handling characteristics of a car-caravan combination different from those of a single vehicle. Therefore, this paper proposes a control design concept for an optimum distribution of longitudinal and lateral forces of the four tires of a towing vehicle. The mean objectives of the control system were to stabilize the motion of an articulated vehicle utilizing the tires entire ability in both longitudinal and lateral directions as well as to make the handling characteristics of an articulated vehicle similar to those of a single one. The sliding control law based on vehicle planar equations of motion is used to derive the control laws. The proposed control system is evaluated under severe driving conditions and compared with the results of integrated control systems. The robustness of the articulated vehicle motion with the proposed control against the coefficient of friction variation is discussed.

  14. Driving forces for home-based reablement; a qualitative study of older adults' experiences.

    Science.gov (United States)

    Hjelle, Kari Margrete; Tuntland, Hanne; Førland, Oddvar; Alvsvåg, Herdis

    2017-09-01

    As a result of the ageing population worldwide, there has been a growing international interest in a new intervention termed 'reablement'. Reablement is an early and time-limited home-based intervention with emphasis on intensive, goal-oriented and interdisciplinary rehabilitation for older adults in need of rehabilitation or at risk of functional decline. The aim of this qualitative study was to describe how older adults experienced participation in reablement. Eight older adults participated in semi-structured interviews. A qualitative content analysis was used as the analysis strategy. Four main themes emerged from the participants' experiences of participating in reablement: 'My willpower is needed', 'Being with my stuff and my people', 'The home-trainers are essential', and 'Training is physical exercises, not everyday activities'. The first three themes in particular reflected the participants' driving forces in the reablement process. Driving forces are intrinsic motivation in interaction with extrinsic motivation. Intrinsic motivation was based on the person's willpower and responsibility, and extrinsic motivation was expressed to be strengthened by being in one's home environment with 'own' people, as well as by the co-operation with the reablement team. The reablement team encouraged and supported the older adults to regain confidence in performing everyday activities as well as participating in the society. Our findings have practical significance for politicians, healthcare providers and healthcare professionals by contributing to an understanding of how intrinsic and extrinsic motivation influence reablement. Some persons need apparently more extrinsic motivational support also after the time-limited reablement period is completed. The municipal health and care services need to consider individualised follow-up programmes after the intensive reablement period in order to maintain the achieved skills to perform everyday activities and participate in

  15. The Key Driving Forces for Geo-Economic Relationships between China and ASEAN Countries

    Directory of Open Access Journals (Sweden)

    Shufang Wang

    2017-12-01

    Full Text Available With the rise of China and the implementation of the “21st Century Maritime Silk Road” strategy, research on geo-economics between China and ASEAN (Association of Southeast Asian Nations countries has become increasingly important. Current studies mainly focus on influencing factors, while there is little consideration about how these influencing factors act on geo-economic relationships. Therefore, this paper explores the key driving forces for geo-economic relationships between China and ASEAN countries by use of the structural equation modeling based on Partial Lease Squares. There are three main findings: (1 Economic factors have the greatest impact on geo-economic relationships and the total path effect is 0.778. Geo-location, geopolitics and geo-culture act on geo-economic relationships directly and indirectly. Their total path effects are 0.731, 0.645 and 0.513, respectively. (2 Indirect effects of geo-location, geopolitics and geo-culture impacting geo-economic relationships are far greater than direct effects. Geo-culture, in particular, has a vital mediating effect on geo-economic relationships. (3 Economic drivers promote geo-economic relationships through market, industrial policy, technical, network and benefit-sharing mechanisms. Political drivers improve geo-economic relationships through cooperation, negotiation, coordination and institutional mechanisms. Cultural drivers enhance geo-economic relationships through transmission mechanism. Location drivers facilitate geo-economic relationships through selection mechanism. We provide new insights on the geo-economic relationships through quantitative analysis and enrich the existing literature by revealing the key driving forces and mechanisms for geo-economic relationships.

  16. NATURE AND DRIVING FORCES OF STRIKE MOVEMENT IN MOLDOVA IN LATE 1980S

    Directory of Open Access Journals (Sweden)

    Галина Евгеньевна Слободянюк

    2016-12-01

    Full Text Available The article discloses the nature and driving forces of the republican protest strike movement in Moldova in the period of perestroika reformsand its impact on the emergence and development of the civil conflict,which became the catalyst for the territorial division of the republic and the creation of the self-proclaimed Transnistrian statehood.In the article there is presented the analysis of the process of formationand activity of the strike movement. The author shows that the United Council of LabourUnionswas the initiator, organizer and the main acting force of the protest of the workers' movement, defending the civil and constitutional rights of the Russian-speaking population of the Transdnistrian region of the Moldavian SSR. The article allows getting an idea of the ways and methods of struggle of the working movement against the Soviet Moldavia nationalist representatives of the Popular front, which operated on the territory of the republic of Moldova. Particular attention is paid to the reasons of occurrence and major activities of the strike movement.Moreover, there are analyzed the consequences of these actions for the further political development of Moldova.

  17. EXTERNAL FORCES DRIVING CHANGE IN THE ROMANIAN SMALL AND MEDIUM SIZED ENTERPRISES

    Directory of Open Access Journals (Sweden)

    Roiban Roxana Nadina

    2012-07-01

    Full Text Available Change is a constant in everyday life confronting organizations to continuously adapt their strategy, structure, processes, and culture in order to survive and stay competitive on the market. Implementing organizational change is one of the most important skills required for managers and in the meantime the most difficult one. The forces driving change within an organization, that can be either external or internal, are those that propel a company forward towards change and in order to identify the need for change and make the proper changes, managers have to develop a tool that allows them to analyze how does the environment influence their business activities. A vision for change will clarify the directions in which the organization needs to move, starting from its current state and taking in consideration the existing opportunities and threats from the environment that allow to move to a future desired state. The purpose of this paper is to identify the concern for change in the Romanian small and medium sized enterprises by presenting and explaining the past and present influences of the main external forces that have determined the need for change in the last 3-5 years and to make recommendations about future possible changes that have to be performed by managers for a better harmonization with the environment. The research method used for this study is the interview on a sample that contains some of the most relevant SME’s from the western side of Romania, from different industries. We analyzed the main external forces that had an impact on the small and medium sized enterprises and how were they generating the need for organizational change, in order to see which present and future changes are required.

  18. Bite force and occlusal stress production in hominin evolution.

    Science.gov (United States)

    Eng, Carolyn M; Lieberman, Daniel E; Zink, Katherine D; Peters, Michael A

    2013-08-01

    Maximum bite force affects craniofacial morphology and an organism's ability to break down foods with different material properties. Humans are generally believed to produce low bite forces and spend less time chewing compared with other apes because advances in mechanical and thermal food processing techniques alter food material properties in such a way as to reduce overall masticatory effort. However, when hominins began regularly consuming mechanically processed or cooked diets is not known. Here, we apply a model for estimating maximum bite forces and stresses at the second molar in modern human, nonhuman primate, and hominin skulls that incorporates skeletal data along with species-specific estimates of jaw muscle architecture. The model, which reliably estimates bite forces, shows a significant relationship between second molar bite force and second molar area across species but does not confirm our hypothesis of isometry. Specimens in the genus Homo fall below the regression line describing the relationship between bite force and molar area for nonhuman anthropoids and australopiths. These results suggest that Homo species generate maximum bite forces below those predicted based on scaling among australopiths and nonhuman primates. Because this decline occurred before evidence for cooking, we hypothesize that selection for lower bite force production was likely made possible by an increased reliance on nonthermal food processing. However, given substantial variability among in vivo bite force magnitudes measured in humans, environmental effects, especially variations in food mechanical properties, may also be a factor. The results also suggest that australopiths had ape-like bite force capabilities. Copyright © 2013 Wiley Periodicals, Inc.

  19. Homologous recombination is a force in the evolution of canine distemper virus.

    Science.gov (United States)

    Yuan, Chaowen; Liu, Wenxin; Wang, Yingbo; Hou, Jinlong; Zhang, Liguo; Wang, Guoqing

    2017-01-01

    Canine distemper virus (CDV) is the causative agent of canine distemper (CD) that is a highly contagious, lethal, multisystemic viral disease of receptive carnivores. The prevalence of CDV is a major concern in susceptible animals. Presently, it is unclear whether intragenic recombination can contribute to gene mutations and segment reassortment in the virus. In this study, 25 full-length CDV genome sequences were subjected to phylogenetic and recombinational analyses. The results of phylogenetic analysis, intragenic recombination, and nucleotide selection pressure indicated that mutation and recombination occurred in the six individual genes segment (H, F, P, N, L, M) of the CDV genome. The analysis also revealed pronounced genetic diversity in the CDV genome according to the geographically distinct lineages (genotypes), namely Asia-1, Asia-2, Asia-3, Europe, America-1, and America-2. The six recombination events were detected using SimPlot and RDP programs. The analysis of selection pressure demonstrated that a majority of the nucleotides in the CDV individual gene were under negative selection. Collectively, these data suggested that homologous recombination acts as a key force driving the genetic diversity and evolution of canine distemper virus.

  20. Current profile evolution during fast wave current drive on the DIII-D tokamak

    International Nuclear Information System (INIS)

    Petty, C.C.; Forest, C.B.; Baity, F.W.

    1995-06-01

    The effect of co and counter fast wave current drive (FWCD) on the plasma current profile has been measured for neutral beam heated plasmas with reversed magnetic shear on the DIII-D tokamak. Although the response of the loop voltage profile was consistent with the application of co and counter FWCD, little difference was observed between the current profiles for the opposite directions of FWCD. The evolution of the current profile was successfully modeled using the ONETWO transport code. The simulation showed that the small difference between the current profiles for co and counter FWCD was mainly due to an offsetting change in the o at sign c current proffie. In addition, the time scale for the loop voltage to reach equilibrium (i.e., flatten) was found to be much longer than the FWCD pulse, which limited the ability of the current profile to fully respond to co or counter FWCD

  1. Blood pressure is the major driving force for plaque formation in aortic-constricted ApoE-/- mice

    DEFF Research Database (Denmark)

    Johansson, Maria E.; Wickman, Anna; Skøtt, Ole

    2006-01-01

    OBJECTIVE: Using an aortic constriction model in mice, we studied whether the increase in pressure or the activation of the renin-angiotensin system (RAS) and its main receptors is the main driving force for plaque progression. METHODS: Male ApoE mice underwent sham surgery or placement of a supr...

  2. Rising electricity consumption: Driving forces and consequences. The case of rural Zanzibar

    Energy Technology Data Exchange (ETDEWEB)

    Winther, Tanja [Centre for Development and the Environment (SUM), Univ. of Oslo (Norway)

    2007-07-01

    The paper addresses the current, rising electricity consumption in the southern, rural locality of Zanzibar and seeks to account for the range of driving forces behind people's changed practices. The author argues that these forces are, on the one hand, determined by the availability of new technologies and through global and national institutions and influences such as Islam, commercials and changes in the governmental sector (health, education). On the other hand, the paper explores the way such influences interplay with the internal dynamics related to increasing consumption. Through an analysis of the particular character and dynamics of social and cultural life in this region, the author explains why some practices are less likely to change than other practices. For example, people in Zanzibar keep electricity (freezers and stoves) at a distance from their food. By contrast, electric light is perceived as intimately related to education, as illustrated when school children are sent to school for night classes before important exams. To which extent may general approaches to the study of energy consumption draw on this empirical case from Zanzibar? In other contexts, the patterns of people's electricity use certainly differ. In terms of sustainable energy policies, each locality has a particular set of challenges and goals, which to varying degree may be related to poverty reduction and concern for the environment. Methodologically, however, the author argues that the phenomenon of energy consumption may be studied and understood within the same framework of analysis; one that pays attention to both external and internal dynamics, the material and social aspects of technologies and the importance of power relations, gender and negotiations.

  3. Assessing LULC changes over Chilika Lake watershed in Eastern India using Driving Force Analysis

    Science.gov (United States)

    Jadav, S.; Syed, T. H.

    2017-12-01

    Rapid population growth and industrial development has brought about significant changes in Land Use Land Cover (LULC) of many developing countries in the world. This study investigates LULC changes in the Chilika Lake watershed of Eastern India for the period of 1988 to 2016. The methodology involves pre-processing and classification of Landsat satellite images using support vector machine (SVM) supervised classification algorithm. Results reveal that `Cropland', `Emergent Vegetation' and `Settlement' has expanded over the study period by 284.61 km², 106.83 km² and 98.83 km² respectively. Contemporaneously, `Lake Area', `Vegetation' and `Scrub Land' have decreased by 121.62 km², 96.05 km² and 80.29 km² respectively. This study also analyzes five major driving force variables of socio-economic and climatological factors triggering LULC changes through a bivariate logistic regression model. The outcome gives credible relative operating characteristics (ROC) value of 0.76 that indicate goodness fit of logistic regression model. In addition, independent variables like distance to drainage network and average annual rainfall have negative regression coefficient values that represent decreased rate of dependent variable (changed LULC) whereas independent variables (population density, distance to road and distance to railway) have positive regression coefficient indicates increased rate of changed LULC . Results from this study will be crucial for planning and restoration of this vital lake water body that has major implications over the society and environment at large.

  4. Climatic driving forces in inter-annual variation of global FPAR

    Science.gov (United States)

    Peng, Dailiang; Liu, Liangyun; Yang, Xiaohua; Zhou, Bin

    2012-09-01

    Fraction of Absorbed Photosynthetically Active Radiation (FPAR) characterizes vegetation canopy functioning and its energy absorption capacity. In this paper, we focus on climatic driving forces in inter-annual variation of global FPAR from 1982 to 2006 by Global Historical Climatology Network (GHCN-Monthly) data. Using FPAR-Simple Ratio Vegetation Index (SR) relationship, Advanced Very High Resolution Radiometer (AVHRR) Global Inventory Modeling and Mapping Studies (GIMMS) Normalized Difference Vegetation Index (NDVI) was used to estimate FPAR at the global scale. The correlation between inter-annual variation of FPAR and temperature, precipitation derived from GHCN-Monthly was examined, during the periods of March-May (MAM), June-August (JJA), September-November (SON), and December-February (DJF) over from 1982 to 2006. The analysis of climatic influence on global FPAR revealed the significant correlation with temperature and precipitation in some meteorological stations area, and a more significant correlation with precipitation was found than which with temperature. Some stations in the regions between 30° N and 60° N and around 30° S in South America, where the annual FPAR variation showed a significant positive correlation with temperature (P forest of Africa and Amazon during the dry season of JJA and SON.

  5. Force Sensitive Handles and Capacitive Touch Sensor for Driving a Flexible Haptic-Based Immersive System

    Directory of Open Access Journals (Sweden)

    Umberto Cugini

    2013-10-01

    Full Text Available In this article, we present an approach that uses both two force sensitive handles (FSH and a flexible capacitive touch sensor (FCTS to drive a haptic-based immersive system. The immersive system has been developed as part of a multimodal interface for product design. The haptic interface consists of a strip that can be used by product designers to evaluate the quality of a 3D virtual shape by using touch, vision and hearing and, also, to interactively change the shape of the virtual object. Specifically, the user interacts with the FSH to move the virtual object and to appropriately position the haptic interface for retrieving the six degrees of freedom required for both manipulation and modification modalities. The FCTS allows the system to track the movement and position of the user’s fingers on the strip, which is used for rendering visual and sound feedback. Two evaluation experiments are described, which involve both the evaluation and the modification of a 3D shape. Results show that the use of the haptic strip for the evaluation of aesthetic shapes is effective and supports product designers in the appreciation of the aesthetic qualities of the shape.

  6. Force sensitive handles and capacitive touch sensor for driving a flexible haptic-based immersive system.

    Science.gov (United States)

    Covarrubias, Mario; Bordegoni, Monica; Cugini, Umberto

    2013-10-09

    In this article, we present an approach that uses both two force sensitive handles (FSH) and a flexible capacitive touch sensor (FCTS) to drive a haptic-based immersive system. The immersive system has been developed as part of a multimodal interface for product design. The haptic interface consists of a strip that can be used by product designers to evaluate the quality of a 3D virtual shape by using touch, vision and hearing and, also, to interactively change the shape of the virtual object. Specifically, the user interacts with the FSH to move the virtual object and to appropriately position the haptic interface for retrieving the six degrees of freedom required for both manipulation and modification modalities. The FCTS allows the system to track the movement and position of the user's fingers on the strip, which is used for rendering visual and sound feedback. Two evaluation experiments are described, which involve both the evaluation and the modification of a 3D shape. Results show that the use of the haptic strip for the evaluation of aesthetic shapes is effective and supports product designers in the appreciation of the aesthetic qualities of the shape.

  7. Casualisation of the nursing workforce in Australia: driving forces and implications.

    Science.gov (United States)

    Creegan, Reta; Duffield, Christine; Forrester, Kim

    2003-01-01

    This article provides an overview of the extent of casualisation of the nursing workforce in Australia, focusing on the impact for those managing the system. The implications for nurse managers in particular are considerable in an industry where service demand is difficult to control and where individual nurses are thought to be increasingly choosing to work casually. While little is known of the reasons behind nurses exercising their preference for casual work arrangements, some reasons postulated include visa status (overseas trained nurses on holiday/working visas); permanent employees taking on additional shifts to increase their income levels; and those who elect to work under casual contracts for lifestyle reasons. Unknown is the demography of the casual nursing workforce, how these groups are distributed within the workforce, and how many contracts of employment they have across the health service--either through privately managed nursing agencies or hospital managed casual pools. A more detailed knowledge of the forces driving the decisions of this group is essential if health care organisations are to equip themselves to manage this changing workforce and maintain a standard of patient care that is acceptable to the community.

  8. Driving forces of organic carbon spatial distribution in the tropical seascape

    Science.gov (United States)

    Gillis, L. G.; Belshe, F. E.; Ziegler, A. D.; Bouma, T. J.

    2017-02-01

    An important ecosystem service of tropical coastal vegetation including seagrass beds and mangrove forests is their ability to accumulate carbon. Here we attempt to establish the driving forces for the accumulation of surface organic carbon in southern Thailand coastal systems. Across 12 sites we found that in line with expectations, seagrass beds (0.6 ± 0.09%) and mangrove forests (0.9 ± 0.3%) had higher organic carbon in the surface (top 5 cm) sediment than un-vegetated mudflats (0.4 ± 0.04%). Unexpectedly, however, mangrove forests in this region retained organic carbon, rather than outwell it, under normal tidal conditions. No relationship was found between organic carbon and substrate grain size. The most interesting finding of our study was that climax and pioneer seagrass species retained more carbon than mixed-species meadows, suggesting that plant morphology and meadow characteristics can be important factors in organic carbon accumulation. Insights such as these are important in developing carbon management strategies involving coastal ecosystems such as offsetting of carbon emissions. The ability of tropical coastal vegetation to sequester carbon is an important aspect for valuing the ecosystems. Our results provide some initial insight into the factors affecting carbon sequestration in these ecosystems, but also highlight the need for further research on a global scale.

  9. Selection for Social Signalling Drives the Evolution of Chameleon Colour Change

    Science.gov (United States)

    Stuart-Fox, Devi; Moussalli, Adnan

    2008-01-01

    Rapid colour change is a remarkable natural phenomenon that has evolved in several vertebrate and invertebrate lineages. The two principal explanations for the evolution of this adaptive strategy are (1) natural selection for crypsis (camouflage) against a range of different backgrounds and (2) selection for conspicuous social signals that maximise detectability to conspecifics, yet minimise exposure to predators because they are only briefly displayed. Here we show that evolutionary shifts in capacity for colour change in southern African dwarf chameleons (Bradypodion spp.) are associated with increasingly conspicuous signals used in male contests and courtship. To the chameleon visual system, species showing the most dramatic colour change display social signals that contrast most against the environmental background and amongst adjacent body regions. We found no evidence for the crypsis hypothesis, a finding reinforced by visual models of how both chameleons and their avian predators perceive chameleon colour variation. Instead, our results suggest that selection for conspicuous social signals drives the evolution of colour change in this system, supporting the view that transitory display traits should be under strong selection for signal detectability. PMID:18232740

  10. Selection for social signalling drives the evolution of chameleon colour change.

    Directory of Open Access Journals (Sweden)

    Devi Stuart-Fox

    2008-01-01

    Full Text Available Rapid colour change is a remarkable natural phenomenon that has evolved in several vertebrate and invertebrate lineages. The two principal explanations for the evolution of this adaptive strategy are (1 natural selection for crypsis (camouflage against a range of different backgrounds and (2 selection for conspicuous social signals that maximise detectability to conspecifics, yet minimise exposure to predators because they are only briefly displayed. Here we show that evolutionary shifts in capacity for colour change in southern African dwarf chameleons (Bradypodion spp. are associated with increasingly conspicuous signals used in male contests and courtship. To the chameleon visual system, species showing the most dramatic colour change display social signals that contrast most against the environmental background and amongst adjacent body regions. We found no evidence for the crypsis hypothesis, a finding reinforced by visual models of how both chameleons and their avian predators perceive chameleon colour variation. Instead, our results suggest that selection for conspicuous social signals drives the evolution of colour change in this system, supporting the view that transitory display traits should be under strong selection for signal detectability.

  11. Study on anti-seismic test of control rod driving system suspended by magnetic force

    International Nuclear Information System (INIS)

    Zhang Zhihua; Qian Dazhi; Xu Xianqi; Huang Hongwen; Zhang Zhengming; Wu Xinxin; Hu Xiao

    2012-01-01

    To verify the stability, reliability and security function in extreme conditions, the anti-seismic test of control rod drive line was conducted. Drop-time of control rod drive line in different earthquake intensities was got. The response and strain values of control rod drive line acceleration on SL-1, SL-2 level were measured. Safety functions of control rod drive line were validated in different work conditions. Anti-seismic test data shows that the driving system can keep the structure's integrality and realize operation function under OBE and SSE. (authors)

  12. Driving forces behind the stagnancy of China's energy-related CO2 emissions from 1996 to 1999: the relative importance of structural change, intensity change and scale change

    International Nuclear Information System (INIS)

    Libo Wu; Kaneko, S.; Matsuoka, S.

    2005-01-01

    It is noteworthy that income elasticity of energy consumption in China shifted from positive to negative after 1996, accompanied by an unprecedented decline in energy-related CO 2 emissions. This paper therefore investigate the evolution of energy-related CO 2 emissions in China from 1985 to 1999 and the underlying driving forces, using the newly proposed three-level 'perfect decomposition' method and provincially aggregated data. The province-based estimates and analyses reveal a 'sudden stagnancy' of energy consumption, supply and energy-related CO 2 emissions in China from 1996 to 1999. The speed of a decrease in energy intensity and a slowdown in the growth of average labor productivity of industrial enterprises may have been the dominant contributors to this 'stagnancy'. The findings of this paper point to the highest rate of deterioration of state-owned enterprises in early 1996, the industrial restructuring caused by changes in ownership, the shutdown of small-scale power plants, and the introduction of policies to improve energy efficiency as probable factors. Taking into account the characteristics of those key driving forces, we characterize China's decline of energy-related CO 2 emissions as a short-term fluctuation and incline to the likelihood that China will resume an increasing trend from a lower starting point in the near future. (author)

  13. Knowing Your Partner: The Evolution of Brazilian Special Operations Forces

    Science.gov (United States)

    2012-08-01

    Group’s Rescue and Retaking Special Group carrying out a counterterrorism tactical exercise. (Photo courtesy Tecnologia & Defesa) Bottom right...Forces Battalion supported by an Army Aviation HM-1 Pantera helicopter; “Operation ASPA” May 2005, Brasilia/Fed- eral District (Photo: Tecnologia ...Defesa) Top right: Amphibious Commandos carry out a maritime infiltration sup- ported by an S34-Tikuna submarine. (Photo: Tecnologia & Defesa) Bottom

  14. Force-chain evolution in a two-dimensional granular packing compacted by vertical tappings

    Science.gov (United States)

    Iikawa, Naoki; Bandi, M. M.; Katsuragi, Hiroaki

    2018-03-01

    We experimentally study the statistics of force-chain evolution in a vertically-tapped two-dimensional granular packing by using photoelastic disks. In this experiment, the tapped granular packing is gradually compacted. During the compaction, the isotropy of grain configurations is quantified by measuring the deviator anisotropy derived from fabric tensor, and then the evolution of force-chain structure is quantified by measuring the interparticle forces and force-chain orientational order parameter. As packing fraction increases, the interparticle force increases and finally saturates to an asymptotic value. Moreover, the grain configurations and force-chain structures become isotropically random as the tapping-induced compaction proceeds. In contrast, the total length of force chains remains unchanged. From the correlations of those parameters, we find two relations: (i) a positive correlation between the isotropy of grain configurations and the disordering of force-chain orientations, and (ii) a negative correlation between the increasing of interparticle forces and the disordering of force-chain orientations. These relations are universally held regardless of the mode of particle motions with or without convection.

  15. Oxidized cholesterol as the driving force behind the development of Alzheimer’s disease

    Directory of Open Access Journals (Sweden)

    Paola eGamba

    2015-06-01

    Full Text Available Alzheimer’s disease (AD, the most common neurodegenerative disorder associated with dementia, is typified by the pathological accumulation of amyloid β peptides and neurofibrillary tangles within the brain. Considerable evidence indicates that many events contribute to AD progression, including oxidative stress, inflammation, and altered cholesterol metabolism.The brain’s high lipid content makes it particularly vulnerable to oxidative species, with the consequent enhancement of lipid peroxidation and cholesterol oxidation, and the subsequent formation of end products, mainly 4-hydroxynonenal and oxysterols, respectively from the two processes. The chronic inflammatory events observed in the AD brain include activation of microglia and astrocytes, together with enhancement of inflammatory molecule and free radical release. Along with glial cells, neurons themselves have been found to contribute to neuroinflammation in the AD brain, by serving as sources of inflammatory mediators. Oxidative stress is intimately associated with neuroinflammation, and a vicious circle has been found to connect oxidative stress and inflammation in AD. Alongside oxidative stress and inflammation, altered cholesterol metabolism and hypercholesterolemia also significantly contribute to neuronal damage and to progression of AD. Increasing evidence is now consolidating the hypothesis that oxidized cholesterol is the driving force behind the development of AD, and that oxysterols are the link connecting the disease to altered cholesterol metabolism in the brain and hypercholesterolemia; this is because of the ability of oxysterols, unlike cholesterol, to cross the blood brain barrier. The key role of oxysterols in AD pathogenesis has been strongly supported by research pointing to their involvement in modulating neuroinflammation, Aβ accumulation, and cell death.This review highlights the key role played by cholesterol and oxysterols in the brain in AD pathogenesis.

  16. How metal films de-wet substrates-identifying the kinetic pathways and energetic driving forces

    International Nuclear Information System (INIS)

    McCarty, Kevin F; Hamilton, John C; Thuermer, Konrad; Jones, Frank; Talin, A Alec; Bartelt, Norman C; Sato, Yu; K Schmid, Andreas; Saa, Angela; Figuera, Juan de la; Stumpf, Roland

    2009-01-01

    We study how single-crystal chromium films of uniform thickness on W(110) substrates are converted to arrays of three-dimensional (3D) Cr islands during annealing. We use low-energy electron microscopy (LEEM) to directly observe a kinetic pathway that produces trenches that expose the wetting layer. Adjacent film steps move simultaneously uphill and downhill relative to the staircase of atomic steps on the substrate. This step motion thickens the film regions where steps advance. Where film steps retract, the film thins, eventually exposing the stable wetting layer. Since our analysis shows that thick Cr films have a lattice constant close to bulk Cr, we propose that surface and interface stress provide a possible driving force for the observed morphological instability. Atomistic simulations and analytic elastic models show that surface and interface stress can cause a dependence of film energy on thickness that leads to an instability to simultaneous thinning and thickening. We observe that de-wetting is also initiated at bunches of substrate steps in two other systems, Ag/W(110) and Ag/Ru(0001). We additionally describe how Cr films are converted into patterns of unidirectional stripes as the trenches that expose the wetting layer lengthen along the W[001] direction. Finally, we observe how 3D Cr islands form directly during film growth at elevated temperature. The Cr mesas (wedges) form as Cr film steps advance down the staircase of substrate steps, another example of the critical role that substrate steps play in 3D island formation.

  17. Analysis of the Driving Forces in Vegetation Variation in the Grain for Green Program Region, China

    Directory of Open Access Journals (Sweden)

    Wang Hao

    2017-10-01

    Full Text Available The Chinese government introduced six ecological restoration programs to improve its natural environment. Although these programs have proven successful in improving local environmental conditions, some studies have questioned their effectiveness when regions suffer from extreme weather conditions. Using the Grain for Green Program (GGP region as a study area, we estimated vegetation activities in the GGP region from 2000 to 2010 to clarify the trends in vegetation growth and their driving forces. The results showed that: (1 vegetation activities improved in the GGP region during 2000-2010, with 58.94% of the area showing an increased trend in the NDVI (normalized difference vegetation index; (2 26.33% of the increased vegetation was caused by human interference, and 11.61% by climate variation, human activity was the dominant cause, and resulted in 54.68% of the degradation compared to 4.74% from climate change; and, (3 the contribution of different land use types to the NDVI interannual variations showed that high contribution regions were focused in the arid and semiarid areas, where the vegetation growth is associated with variations in recipitation and temperature. However, conversions between farmland and grassland or forest had a significant effect on the change in the NDVI trend. Therefore, although climate conditions can affect vegetation growth, human activities are more important in vegetation changes, and appropriate human activities would contribute to its continual improvement. Hence, we recommend establishing an assessment and scientific management mechanism for eco-risks in the design and management of ecosystem restoration programs.

  18. A drastic reorganization of industry in the world.What is the driving force

    Directory of Open Access Journals (Sweden)

    Shinji Naruo

    2010-05-01

    Full Text Available The purpose of this paper is to show the method and model to analyze the driving force to reorganize the industry. Due to the global economy, many large scale M&A and affiliations are happening in the world. The business alliance and integration are happening in the advanced countries, the transition countries, and the developing countries. There are some factors to impact the reorganization of industry. One is government policy. Another is the market economy. The government has the industrial policy. It guides and leads the industrial structure of the country. Advanced countries had experienced the advancement of industrial structure. On the process of industrial structure advancement, the country improved national income (GNP. Through the process, the enterprise in the industry had experienced integration and separation in the industry. The theory of industrial structure supports the framework of this approach.On the other hand, the market economy also had influenced to the reorganization of industry. Business cycle, competition, and innovation had influenced the reorganization of industry. In capitalism, the shareholder of the company pushes the company to maximize the profit. The shareholder’s pressure could influence the decision of M&A.The theory of industrial organization supports the framework of this approach.The enterprise is in the business environment. Top management of the company is responsible to make a decision to merge or acquire the company. However, the decision is affected by other factors out of business environment. The shareholder influenced the individual enterprise decision. The government policy influenced the industrial structure. This could impose the enterprise to accept the amalgamation in the industry.Both of two influence the reorganization of industry.

  19. Time evolution of tropospheric ozone and its radiative forcing

    International Nuclear Information System (INIS)

    Berntsen, Terje K.; Isaksen, Ivar S.A.; Myhre, Gunnar; Stordal, Frode

    1999-01-01

    The overview presents results from studies of ozone concentrations from pre industrial time and up to the end of the 20th century. Different models and also a global 3-D chemistry transport model have been used. Experiments have been performed for 1850, 1900, 1950, 1960, 1970, 1980 and 1990. The radiative forcing increases with increasing ozone levels and has been steadily increasing. It has escalated towards the end of the century. Comparative evaluations with project results and external results are presented. Connections to other greenhouse gases are mentioned

  20. Can foraging ecology drive the evolution of body size in a diving endotherm?

    Directory of Open Access Journals (Sweden)

    Timothée R Cook

    Full Text Available Within a single animal species, different morphs can allow for differential exploitation of foraging niches between populations, while sexual size dimorphism can provide each sex with access to different resources. Despite being potentially important agents of evolution, resource polymorphisms, and the way they operate in wild populations, remain poorly understood. In this study, we examine how trophic factors can select for different body sizes between populations and sexes in a diving endotherm. Dive depth and duration are positively related to body size in diving birds and mammals, a relationship explained by a lower mass-specific metabolic rate and greater oxygen stores in larger individuals. Based on this allometry, we predict that selection for exploiting resources situated at different depths can drive the evolution of body size in species of diving endotherms at the population and sexual level. To test this prediction, we studied the foraging ecology of Blue-eyed Shags, a group of cormorants with male-biased sexual size dimorphism from across the Southern Ocean. We found that mean body mass and relative difference in body mass between sexes varied by up to 77% and 107% between neighbouring colonies, respectively. Birds from colonies with larger individuals dived deeper than birds from colonies with smaller individuals, when accounting for sex. In parallel, males dived further offshore and deeper than females and the sexual difference in dive depth reflected the level of sexual size dimorphism at each colony. We argue that body size in this group of birds is under intense selection for diving to depths of profitable benthic prey patches and that, locally, sexual niche divergence selection can exaggerate the sexual size dimorphism of Blue-eyed Shags initially set up by sexual selection. Our findings suggest that trophic resources can select for important geographic micro-variability in body size between populations and sexes.

  1. Directed motion of spheres induced by unbiased driving forces in viscous fluids beyond the Stokes' law regime

    Science.gov (United States)

    Casado-Pascual, Jesús

    2018-03-01

    The emergence of directed motion is investigated in a system consisting of a sphere immersed in a viscous fluid and subjected to time-periodic forces of zero average. The directed motion arises from the combined action of a nonlinear drag force and the applied driving forces, in the absence of any periodic substrate potential. Necessary conditions for the existence of such directed motion are obtained and an analytical expression for the average terminal velocity is derived within the adiabatic approximation. Special attention is paid to the case of two mutually perpendicular forces with sinusoidal time dependence, one with twice the period of the other. It is shown that, although neither of these two forces induces directed motion when acting separately, when added together, the resultant force generates directed motion along the direction of the force with the shortest period. The dependence of the average terminal velocity on the system parameters is analyzed numerically and compared with that obtained using the adiabatic approximation. Among other results, it is found that, for appropriate parameter values, the direction of the average terminal velocity can be reversed by varying the forcing strength. Furthermore, certain aspects of the observed phenomenology are explained by means of symmetry arguments.

  2. Sector trends and driving forces of global energy use and greenhouse gas emissions: focus in industry and buildings

    Energy Technology Data Exchange (ETDEWEB)

    Price, Lynn; Worrell, Ernst; Khrushch, Marta

    1999-09-01

    Disaggregation of sectoral energy use and greenhouse gas emissions trends reveals striking differences between sectors and regions of the world. Understanding key driving forces in the energy end-use sectors provides insights for development of projections of future greenhouse gas emissions. This report examines global and regional historical trends in energy use and carbon emissions in the industrial, buildings, transport, and agriculture sectors, with a more detailed focus on industry and buildings. Activity and economic drivers as well as trends in energy and carbon intensity are evaluated. The authors show that macro-economic indicators, such as GDP, are insufficient for comprehending trends and driving forces at the sectoral level. These indicators need to be supplemented with sector-specific information for a more complete understanding of future energy use and greenhouse gas emissions.

  3. Differences in Pattern and Driving Forces between Urban and Rural Settlements in the Coastal Region of Ningbo, China

    Directory of Open Access Journals (Sweden)

    Mingxing Chen

    2014-04-01

    Full Text Available Rapid urbanization on the coast of China has attracted much attention. The objective of this study was to explore the differences in dynamics and related driving forces between urban and rural settlements. Applying the quantitative method, we demonstrate that substantial heterogeneity in settlement growth, landscape pattern metrics, change, land sources and driving forces is exhibited across the different types of urban and rural settlements. The spatial growth of urban settlements is dominated by in situ expansion, while rural settlements tend to be scattered and shrinking rapidly. The sprawl of human settlements has mainly occupied farm land, but reclamation projects are increasingly becoming important land sources for urban settlements. Local government has played a critical role in urban settlements, while the expansion of rural settlements is mainly driven by individual choice and village collective organizations. Such differences may account for differential options for the management of human settlements scientifically.

  4. Deformation-induced martensitic transformation in a 201 austenitic steel: The synergy of stacking fault energy and chemical driving force

    Energy Technology Data Exchange (ETDEWEB)

    Moallemi, M., E-mail: m.moallemi@ma.iut.ac.ir [Department of Materials Engineering, Isfahan University of Technology, Isfahan 84156-83111 (Iran, Islamic Republic of); Kermanpur, A. [Department of Materials Engineering, Isfahan University of Technology, Isfahan 84156-83111 (Iran, Islamic Republic of); Najafizadeh, A. [Department of Materials Engineering, Isfahan University of Technology, Isfahan 84156-83111 (Iran, Islamic Republic of); Fould Institute of Technology, Fouladshahr, Isfahan, 8491663763 (Iran, Islamic Republic of); Rezaee, A.; Baghbadorani, H. Samaei; Nezhadfar, P. Dastranjy [Department of Materials Engineering, Isfahan University of Technology, Isfahan 84156-83111 (Iran, Islamic Republic of)

    2016-01-20

    The present study deals with the correlation of stacking fault energy's synergy and driving force in the formation of deformation-induced martensitic transformation in a 201 austenitic stainless steel. The fraction of deformation-induced martensite was characterized by means of X-ray diffraction and magnetic induction techniques. The kinetics of the martensite formation versus applied strain was evaluated through the sigmoidal model. It was shown that the volume fraction of ά-martensite is closely related to the driving force/SFE ratio of the alloy. The results also showed that the martensite content is similar in both XRD and magnetic methods and the applied sigmoidal model was consistent with the obtained experimental data.

  5. Sector trends and driving forces of global energy use and greenhouse gas emissions: focus in industry and buildings

    International Nuclear Information System (INIS)

    Price, Lynn; Worrell, Ernst; Khrushch, Marta

    1999-01-01

    Disaggregation of sectoral energy use and greenhouse gas emissions trends reveals striking differences between sectors and regions of the world. Understanding key driving forces in the energy end-use sectors provides insights for development of projections of future greenhouse gas emissions. This report examines global and regional historical trends in energy use and carbon emissions in the industrial, buildings, transport, and agriculture sectors, with a more detailed focus on industry and buildings. Activity and economic drivers as well as trends in energy and carbon intensity are evaluated. The authors show that macro-economic indicators, such as GDP, are insufficient for comprehending trends and driving forces at the sectoral level. These indicators need to be supplemented with sector-specific information for a more complete understanding of future energy use and greenhouse gas emissions

  6. Effects of electron cyclotron current drive on the evolution of double tearing mode

    International Nuclear Information System (INIS)

    Sun, Guanglan; Dong, Chunying; Duan, Longfang

    2015-01-01

    The effects of electron cyclotron current drive (ECCD) on the double tearing mode (DTM) in slab geometry are investigated by using two-dimensional compressible magnetohydrodynamics equations. It is found that, mainly, the double tearing mode is suppressed by the emergence of the secondary island, due to the deposition of driven current on the X-point of magnetic island at one rational surface, which forms a new non-complete symmetric magnetic topology structure (defined as a non-complete symmetric structure, NSS). The effects of driven current with different parameters (magnitude, initial time of deposition, duration time, and location of deposition) on the evolution of DTM are analyzed elaborately. The optimal magnitude or optimal deposition duration of driven current is the one which makes the duration of NSS the longest, which depends on the mutual effect between ECCD and the background plasma. Moreover, driven current introduced at the early Sweet-Parker phase has the best suppression effect; and the optimal moment also exists, depending on the duration of the NSS. Finally, the effects varied by the driven current disposition location are studied. It is verified that the favorable location of driven current is the X-point which is completely different from the result of single tearing mode

  7. Effects of electron cyclotron current drive on the evolution of double tearing mode

    Energy Technology Data Exchange (ETDEWEB)

    Sun, Guanglan, E-mail: sunguanglan@nciae.edu.cn; Dong, Chunying [Basic Science Section, North China Institute of Aerospace Engineering, Langfang 065000 (China); Duan, Longfang [School of Computer and Remote Sensing Information Technology, North China Institute of Aerospace Engineering, Langfang 065000 (China)

    2015-09-15

    The effects of electron cyclotron current drive (ECCD) on the double tearing mode (DTM) in slab geometry are investigated by using two-dimensional compressible magnetohydrodynamics equations. It is found that, mainly, the double tearing mode is suppressed by the emergence of the secondary island, due to the deposition of driven current on the X-point of magnetic island at one rational surface, which forms a new non-complete symmetric magnetic topology structure (defined as a non-complete symmetric structure, NSS). The effects of driven current with different parameters (magnitude, initial time of deposition, duration time, and location of deposition) on the evolution of DTM are analyzed elaborately. The optimal magnitude or optimal deposition duration of driven current is the one which makes the duration of NSS the longest, which depends on the mutual effect between ECCD and the background plasma. Moreover, driven current introduced at the early Sweet-Parker phase has the best suppression effect; and the optimal moment also exists, depending on the duration of the NSS. Finally, the effects varied by the driven current disposition location are studied. It is verified that the favorable location of driven current is the X-point which is completely different from the result of single tearing mode.

  8. Uncovering driving forces on greenhouse gas emissions in China’ aluminum industry from the perspective of life cycle analysis

    International Nuclear Information System (INIS)

    Liu, Zhe; Geng, Yong; Adams, Michelle; Dong, Liang; Sun, Lina; Zhao, Jingjing; Dong, Huijuan; Wu, Jiao; Tian, Xu

    2016-01-01

    Highlights: • Energy-related GHG emission trajectories, features and driving forces of CAI are analyzed from the perspective of LCA. • CAI experienced a rapid growth of energy-related GHG emissions from 2004 to 2013. • Energy-scale effect is the main driving force for energy-related GHG emissions increase in CAI. • Construction and transportation-related activities account for more than 40% of the total embodied emissions. • Policy implications such as developing secondary aluminum industry, improving energy mix etc, are raised. - Abstract: With the rapid growth of aluminum production, reducing greenhouse gas (GHG) emissions in China’s aluminum industry (CAI) is posing a significant challenge. In this study, the energy-related GHG emission trajectories, features and driving forces of CAI are analyzed from the perspective of life cycle analysis (LCA) from 2004 to 2013. Results indicate that CAI experienced a rapid growth of energy-related GHG emissions with an average annual growth of 28.5 million tons CO_2e from 2004 to 2013. Energy-scale effect is the main driving force for energy-related GHG emissions increase in CAI, while emission-factor effect of secondary aluminum production plays a marginal effect. Construction and transportation-related activities account for the bulk of the embodied emissions, accounting for more than 40% of the total embodied emissions from CAI. Policy implications for GHG mitigation within the CAI, such as developing secondary aluminum industry, improving energy mix and optimizing resource efficiency of production, are raised.

  9. Meeting the challenges of the new energy industry: The driving forces facing electric power generators and the natural gas industry

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    The proceedings of the IGT national conference on meeting the challenges of the New Energy Industry: The driving forces facing Electric Power Generators and the Natural Gas Industry are presented. The conference was held June 19-21, 1995 at the Ambassador West Hotel in Downtown Chicago, Illinois. A separate abstract and indexing for each of the 18 papers presented for inclusion in the Energy Science and Technology Database.

  10. The Driving Forces for the Practice of Strategic Planning in SMEs: Evidence from Harare Metropolitan Province, Zimbabwe

    OpenAIRE

    Maxwell Sandada; Raynold Tinomudaishe Chikwama

    2016-01-01

    Despite Zimbabwe sharing with the rest of the world, the notion that SMEs are the impeccable engines to economic revival, growth and development, many of the nation`s SMEs are plagued with high failure rates. Previous studies carried out in most foreign countries suggested that the high failure rate of SMEs was attributable to lack of strategic planning among a host of other factors. Against this backdrop, the purpose of this study was to examine the driving forces for the practic...

  11. Meeting the challenges of the new energy industry: The driving forces facing electric power generators and the natural gas industry

    International Nuclear Information System (INIS)

    Anon.

    1995-01-01

    The proceedings of the IGT national conference on meeting the challenges of the New Energy Industry: The driving forces facing Electric Power Generators and the Natural Gas Industry are presented. The conference was held June 19-21, 1995 at the Ambassador West Hotel in Downtown Chicago, Illinois. A separate abstract and indexing for each of the 18 papers presented for inclusion in the Energy Science and Technology Database

  12. Measuring Risky Driving Behavior Using an mHealth Smartphone App: Development and Evaluation of gForce

    Science.gov (United States)

    Dave, Amisha D; Espey, Benjamin G; Stanley, Sean T; Garmendia, Marcial A; Pursley, Randall; Ehsani, Johnathon P; Simons-Morton, Bruce G; Pohida, Thomas J

    2018-01-01

    Background Naturalistic driving studies, designed to objectively assess driving behavior and outcomes, are conducted by equipping vehicles with dedicated instrumentation (eg, accelerometers, gyroscopes, Global Positioning System, and cameras) that provide continuous recording of acceleration, location, videos, and still images for eventual retrieval and analyses. However, this research is limited by several factors: the cost of equipment installation; management and storage of the large amounts of data collected; and data reduction, coding, and analyses. Modern smartphone technology includes accelerometers built into phones, and the vast, global proliferation of smartphones could provide a possible low-cost alternative for assessing kinematic risky driving. Objective We evaluated an in-house developed iPhone app (gForce) for detecting elevated g-force events by comparing the iPhone linear acceleration measurements with corresponding acceleration measurements obtained with both a custom Android app and the in-vehicle miniDAS data acquisition system (DAS; Virginia Tech Transportation Institute). Methods The iPhone and Android devices were dashboard-mounted in a vehicle equipped with the DAS instrumentation. The experimental protocol consisted of driving maneuvers on a test track, such as cornering, braking, and turning that were performed at different acceleration levels (ie, mild, moderate, or hard). The iPhone gForce app recorded linear acceleration (ie, gravity-corrected). The Android app recorded gravity-corrected and uncorrected acceleration measurements, and the DAS device recorded gravity-uncorrected acceleration measurements. Lateral and longitudinal acceleration measures were compared. Results The correlation coefficients between the iPhone and DAS acceleration measurements were slightly lower compared to the correlation coefficients between the Android and DAS, possibly due to the gravity correction on the iPhone. Averaging the correlation coefficients for

  13. Driving force of PCMI failure under reactivity initiated accident conditions and influence of hydrogen embrittlement on failure limit

    International Nuclear Information System (INIS)

    Tomiyasu, Kunihiko; Sugiyama, Tomoyuki; Nakamura, Takehiko; Fuketa, Toyoshi

    2005-09-01

    In order to clarify the driving force of PCMI (Pellet/Cladding Mechanical Interaction) failure on high burnup fuels and to investigate the influence of hydrogen embrittlement on failure limit under RIA (Reactivity Initiated Accident) conditions, RIA-simulation experiments were performed on fresh fuel rods in the NSRR (Nuclear Safety Research Reactor). The driving force of PCMI was restricted only to thermal expansion of pellet by using fresh UO 2 pellets. Fresh claddings were pre-hydrided to simulate hydrogen absorption of high burnup fuel rods. In seven experiments out of fourteen, test rods resulted in PCMI failure, which has been observed in the NSRR tests on high burnup PWR fuels, in terms of the transient behavior and the fracture configuration. This indicates that the driving force of PCMI failure is sufficiently explained with thermal expansion of pellet and a contribution of fission gas on it is small. A large number of incipient cracks were generated in the outer surface of the cladding even on non-failed fuel rods, and they stopped at the boundary between hydride rim, which was a hydride layer localized in the periphery of the cladding, and metallic layer. It suggests that the integrity of the metallic layer except for the hydride rim has particular importance for failure limit. Fuel enthalpy at failure correlates with the thickness of hydride rim, and tends to decrease with thicker hydride layer. (author)

  14. Insights on landscape evolution and climatic forcing on Titan

    Science.gov (United States)

    Lucas, A.; Daudon, C.; Rodriguez, S.; Cornet, T.; Perron, J. T.

    2017-12-01

    The landscapes of Titan were observed for nearly 13 years by the Cassini spacecraft and Huygens probe. With dunes, mountains, seas, lakes, rivers..., the great morphological variety observed testifies to the geological richness that Titan shares with the Earth. In this study, we combine analysis of radar and hyperspectral data provided by the Cassini-Huygens mission, with models of valley and river network evolution to better understand the processes at work that sculpt these familiar landscapes. We develop quantitative criteria for comparing 3D morphologies obtained by numerical simulation with those derived for Titan by photogrammetry. These criteria are validated on Earth's landscapes. We simulate morphologies similar to those observed and show that landscapes at the equator and poles are mainly controlled by river incision and mass wasting such as landslides for which we quantify their respective contribution. Subsequently, we relate modeling to precipitation rates of methane and show values that are to be compared with general circulation model predictions (GCM). Our results also show a very young age of formation of the observed morphologies, less than a few million years. Finally, we provide new constraints on current amplitude of the tidal effects and organic precipitation rates from atmosphere chemistry.

  15. Quantifying the Driving Forces of Informal Urbanization in the Western Part of the Greater Cairo Metropolitan Region

    Directory of Open Access Journals (Sweden)

    Taher Osman

    2016-06-01

    Full Text Available This paper discusses the driving forces (DFs of informal urbanization (IU in the greater Cairo metropolitan region (GCMR using the Analytic Hierarchy Process (AHP. The IU patterns in the GCMR have been extremely influenced by seven DFs: geographical characteristics, availability of life facilities, economic incentives, land demand and supply, population increase, administrative function, and development plans. This research found that these forces vary significantly in how they influence urban growth in the three study sectors, namely, the middle, north, and south areas in the western part of the GCMR. The forces with the highest influence were economic incentives in the middle sector, population increase in the north sector, and the administrative function in the south sector. Due to the lower availability of buildable land in the middle sector, the land demand and supply force had a lesser influence in this sector compared to in the north and south sectors. The development plans force had medium influence in all sectors. The geographical characteristics force had little influence in both the middle and the north sectors, but higher influence than economic incentives, availability of life facilities, and development plans in the south sector. Because of the spatial variances in life facilities organizations in the GCMR, the life facilities availability force had little effect on IU in the south sector.

  16. Range expansion drives dispersal evolution in an equatorial three-species symbiosis.

    Directory of Open Access Journals (Sweden)

    Guillaume Léotard

    Full Text Available Recurrent climatic oscillations have produced dramatic changes in species distributions. This process has been proposed to be a major evolutionary force, shaping many life history traits of species, and to govern global patterns of biodiversity at different scales. During range expansions selection may favor the evolution of higher dispersal, and symbiotic interactions may be affected. It has been argued that a weakness of climate fluctuation-driven range dynamics at equatorial latitudes has facilitated the persistence there of more specialized species and interactions. However, how much the biology and ecology of species is changed by range dynamics has seldom been investigated, particularly in equatorial regions.We studied a three-species symbiosis endemic to coastal equatorial rainforests in Cameroon, where the impact of range dynamics is supposed to be limited, comprised of two species-specific obligate mutualists--an ant-plant and its protective ant--and a species-specific ant parasite of this mutualism. We combined analyses of within-species genetic diversity and of phenotypic variation in a transect at the southern range limit of this ant-plant system. All three species present congruent genetic signatures of recent gradual southward expansion, a result compatible with available regional paleoclimatic data. As predicted, this expansion has been accompanied by the evolution of more dispersive traits in the two ant species. In contrast, we detected no evidence of change in lifetime reproductive strategy in the tree, nor in its investment in food resources provided to its symbiotic ants.Despite the decreasing investment in protective workers and the increasing investment in dispersing females by both the mutualistic and the parasitic ant species, there was no evidence of destabilization of the symbiosis at the colonization front. To our knowledge, we provide here the first evidence at equatorial latitudes that biological traits associated

  17. Range expansion drives dispersal evolution in an equatorial three-species symbiosis.

    Science.gov (United States)

    Léotard, Guillaume; Debout, Gabriel; Dalecky, Ambroise; Guillot, Sylvain; Gaume, Laurence; McKey, Doyle; Kjellberg, Finn

    2009-01-01

    Recurrent climatic oscillations have produced dramatic changes in species distributions. This process has been proposed to be a major evolutionary force, shaping many life history traits of species, and to govern global patterns of biodiversity at different scales. During range expansions selection may favor the evolution of higher dispersal, and symbiotic interactions may be affected. It has been argued that a weakness of climate fluctuation-driven range dynamics at equatorial latitudes has facilitated the persistence there of more specialized species and interactions. However, how much the biology and ecology of species is changed by range dynamics has seldom been investigated, particularly in equatorial regions. We studied a three-species symbiosis endemic to coastal equatorial rainforests in Cameroon, where the impact of range dynamics is supposed to be limited, comprised of two species-specific obligate mutualists--an ant-plant and its protective ant--and a species-specific ant parasite of this mutualism. We combined analyses of within-species genetic diversity and of phenotypic variation in a transect at the southern range limit of this ant-plant system. All three species present congruent genetic signatures of recent gradual southward expansion, a result compatible with available regional paleoclimatic data. As predicted, this expansion has been accompanied by the evolution of more dispersive traits in the two ant species. In contrast, we detected no evidence of change in lifetime reproductive strategy in the tree, nor in its investment in food resources provided to its symbiotic ants. Despite the decreasing investment in protective workers and the increasing investment in dispersing females by both the mutualistic and the parasitic ant species, there was no evidence of destabilization of the symbiosis at the colonization front. To our knowledge, we provide here the first evidence at equatorial latitudes that biological traits associated with dispersal are

  18. Gravity drives the evolution of infrared dark hubs: JVLA observations of SDC13

    Science.gov (United States)

    Williams, G. M.; Peretto, N.; Avison, A.; Duarte-Cabral, A.; Fuller, G. A.

    2018-05-01

    Context. Converging networks of interstellar filaments, that is hubs, have been recently linked to the formation of stellar clusters and massive stars. Understanding the relationship between the evolution of these systems and the formation of cores and stars inside them is at the heart of current star formation research. Aims: The goal is to study the kinematic and density structure of the SDC13 prototypical hub at high angular resolution to determine what drives its evolution and fragmentation. Methods: We have mapped SDC13, a 1000 M⊙ infrared dark hub, in NH3(1,1) and NH3(2,2) emission lines, with both the Jansky Very Large Array and Green Bank Telescope. The high angular resolution achieved in the combined dataset allowed us to probe scales down to 0.07 pc. After fitting the ammonia lines, we computed the integrated intensities, centroid velocities and line widths, along with gas temperatures and H2 column densities. Results: The mass-per-unit-lengths of all four hub filaments are thermally super-critical, consistent with the presence of tens of gravitationally bound cores identified along them. These cores exhibit a regular separation of 0.37 ± 0.16 pc suggesting gravitational instabilities running along these super-critical filaments are responsible for their fragmentation. The observed local increase of the dense gas velocity dispersion towards starless cores is believed to be a consequence of such fragmentation process. Using energy conservation arguments, we estimate that the gravitational to kinetic energy conversion efficiency in the SDC13 cores is 35%. We see velocity gradient peaks towards 63% of cores as expected during the early stages of filament fragmentation. Another clear observational signature is the presence of the most massive cores at the filaments' junction, where the velocity dispersion is largest. We interpret this as the result of the hub morphology generating the largest acceleration gradients near the hub centre. Conclusions: We

  19. Driving forces of main landscape change processes from past 200 years in Central Europe - differences between old democratic and post-socialist countries

    Directory of Open Access Journals (Sweden)

    Skokanová Hana

    2016-03-01

    Full Text Available The article compares and points out differences in driving forces of four main landscape change processes that shaped post-socialist countries and old democratic countries of Central Europe during the last two centuries. Studying landscape change processes and corresponding driving forces helps in understanding patterns of present landscape and can help among others in better prediction of future landscape change trends. Here, the presented results are based on review of scientific articles published in peer-reviewed journals between 2000 and 2014. Driving forces affecting these processes were grouped into four categories. Economic forces drove mainly agricultural intensification; agricultural land abandonment and urbanisation and were pronounced especially in the second half of the 20th century and at the beginning of the 21st century. Technological driving forces affected agricultural intensification especially in the 19th century and the second half of the 20th century while cultural driving forces had the biggest impact on urbanisation at the beginning of the 21st century. Political driving forces affected agricultural intensification, urbanisation as well as agricultural land abandonment and were pronounced mainly during the second half of the 20th century in the post-socialist countries. Political forces in the form of subsidies drove agricultural extensification at the beginning of the 21st century. The drivers for the agricultural intensification as well as urbanisation seem to be similar for both old democratic and post-socialist countries. In contrast, agricultural land abandonment in the old democratic countries was driven by technological, cultural and economic driving forces while in the post-socialist countries the political driving forces were mainly responsible. Changes in systems for subsidies and changes in the agricultural commodity markets are also responsible for different frequencies and rates of extensification of

  20. The Other Quiet Professionals: Lessons for Future Cyber Forces from the Evolution of Special Forces

    Science.gov (United States)

    2014-01-01

    tions Command), John Mense (INSCOM), Paul Schuh (JFCC-NW), Russell Fenton (U.S. Army Network Enterprise Technology Command), and CW5 Todd Boudreau and...Surdu, 2009, pp. 16–17). Doctrine Irregular warfare and SOF doctrine lagged operational activities after the Vietnam War and prior to the...forces are, at their operating core, small teams of highly skilled specialists, and both communities value skilled personnel above all else. Irregular

  1. Positive Selection Driving Cytoplasmic Genome Evolution of the Medicinally Important Ginseng Plant Genus Panax.

    Science.gov (United States)

    Jiang, Peng; Shi, Feng-Xue; Li, Ming-Rui; Liu, Bao; Wen, Jun; Xiao, Hong-Xing; Li, Lin-Feng

    2018-01-01

    Panax L. (the ginseng genus) is a shade-demanding group within the family Araliaceae and all of its species are of crucial significance in traditional Chinese medicine. Phylogenetic and biogeographic analyses demonstrated that two rounds of whole genome duplications accompanying with geographic and ecological isolations promoted the diversification of Panax species. However, contributions of the cytoplasmic genomes to the adaptive evolution of Panax species remained largely uninvestigated. In this study, we sequenced the chloroplast and mitochondrial genomes of 11 accessions belonging to seven Panax species. Our results show that heterogeneity in nucleotide substitution rate is abundant in both of the two cytoplasmic genomes, with the mitochondrial genome possessing more variants at the total level but the chloroplast showing higher sequence polymorphisms at the genic regions. Genome-wide scanning of positive selection identified five and 12 genes from the chloroplast and mitochondrial genomes, respectively. Functional analyses further revealed that these selected genes play important roles in plant development, cellular metabolism and adaptation. We therefore conclude that positive selection might be one of the potential evolutionary forces that shaped nucleotide variation pattern of these Panax species. In particular, the mitochondrial genes evolved under stronger selective pressure compared to the chloroplast genes.

  2. Analysis and optimization of kinematic pair force in control rod drive mechanism

    International Nuclear Information System (INIS)

    Sun Zhenguo; Liu Sen; Ran Xiaobing; Dai Changnian; Li Yuezhong

    2015-01-01

    Function expressions of kinematic pair force with latch dimensions, friction coefficient, link angle and external load was obtained by theoretical analysis, and the expression was verified by the motion analysis software. Key parameters of kinematic pair were confirmed, and their effect trends with force of parts were obtained. They show that the available method of kinematic pair optimization is increasing the space of latch holes. Using the motion analysis software, the forces of parts before and after optimization was compared. The result shows that the forces of parts were improved after the optimization. (authors)

  3. Understanding the driving forces behind the losses of soil carbon across England and Wales

    Science.gov (United States)

    Bellamy, Patricia

    2010-05-01

    More than twice as much carbon is held in soils as in vegetation or the atmosphere, and changes in soil carbon content can have a large effect on the global carbon budget. The possibility that climate change is being reinforced by increased carbon dioxide emissions from soils owing to rising temperature is the subject of a continuing debate. But evidence for the suggested feedback mechanism has to date come solely from small-scale laboratory and field experiments and modelling studies. Here we use data from the National Soil Inventory of England and Wales obtained between 1978 and 2003 to show that carbon was lost from soils across England and Wales over the survey period at a mean rate of 0.6% yr-1 (relative to the existing soil carbon content). We find that the relative rate of carbon loss increased with soil carbon content and was more than 2% yr-1 in soils with carbon contents greater than 100 g kg-1. The relationship between rate of carbon loss and carbon content is irrespective of land use, suggesting a link to climate change. Our findings indicate that losses of soil carbon in England and Wales—and by inference in other temperate regions—are likely to have been offsetting absorption of carbon by terrestrial sinks. To investigate the possible driving forces of the measured losses of soil carbon we applied a simple model of soil carbon turnover to evaluate alternative explanations for the observed trends. We find that neither changes in decomposition resulting from the effects of climate change on soil temperature and moisture, nor changes in carbon input from vegetation, could account on their own for the overall trends. Of other explanations, results indicate that past changes in land use and management were probably dominant. The climate change signal, such as it is, is masked by these other changes. A more sophisticated model of carbon change (DAYCENT) has now been applied across the whole range of soils in England and Wales. This model has been

  4. Disruptive Innovations as a Driving Force for the Change of Wireless Telecommunication Infrastructures

    DEFF Research Database (Denmark)

    Kyoseva, Tsvetoslava; Poulkov, Vladimir; Mihaylov, Mihail Rumenov

    2014-01-01

    the current trends in mobile communications, we reason that the emergence of new telecommunication architectures and infrastructures is inevitable. An important consideration in the analysis is the driving role of disruptive technologies for the future of telecommunications. Based on a model for evaluating...

  5. FDR (drive-dynamics-control) - a new driving safety system with active control of brake and drive forces in the dynamic fringe range; FDR, ein neues Fahrsicherheitssystem mit aktiver Regelung der Brems- und Antriebskraefte im fahrdynamischen Grenzbereich

    Energy Technology Data Exchange (ETDEWEB)

    Erhardt, R. [Bosch (R.) GmbH, Stuttgart (Germany); Zanten, A.T. van [Bosch (R.) GmbH, Stuttgart (Germany)

    1995-12-31

    BOSCH is going to introduce a new driving safety system in 1995, the FDR (drive-dynamics-control). Using the measured and estimated dynamic magnitudes as a basis, the system calculates inhowfar the actual vehicle motion differs from the desired stable trace- and direction-consistent handling properties. Depending on the driving situation and driver`s wishes the braking and driving forces at the wheels are adjusted with a considerable divergence in order to achieve the desired handling properties. The system improves the driving stability in all operating states as soon as the dynamic limiting range is reached. It even reduces the risk of skidding in case of extreme steering manoeuvres and also enables the safe control of the vehicle in critical traffic situations. Furthermore the system offers improved basic anti-skid braking system and anti-slip control functions. Due to these advantages it can be expected that the FDR is going to make an important contribution to avoiding accidents and reducing damage. (orig.) [Deutsch] Mit FDR (Fahr-Dynamik-Regelung) wird BOSCH 1995 ein neues Fahrsicherheitssystem einfuehren. Das System berechnet auf der Basis gemessener und geschaetzter fahrdynamischer Groessen, wie stark die tatsaechliche Fahrzeugbewegung von einem gewuenschten stabilen, spur- und richtungstreuen Fahrverhalten abweicht. Die Brems- und Antriebskraefte an den Raedern werden bei deutlicher Abweichung abhaengig von Fahrsituation und Fahrerwunsch so eingestellt, dass die Abweichung minimiert und das gewuenschte Fahrverhalten weitgehend erreicht wird. Das System verbessert die Fahrstabilitaet in allen Betriebszustaenden, sobald der fahrdynamische Grenzbereich erreicht wird. Es reduziert selbst bei extremen Lenkmanoevern die Schleudergefahr drastisch und ermoeglicht auch in kritischen Verkehrssituationen die sicherere Beherrschung des Fahrzeugs. Darueberhinaus bietet das System verbesserte ABS- und ASR-Grundfunktionen. Diese Vorteile lassen erwarten, dass FDR einen

  6. Counterevidence to the ion hammering scenario as a driving force for the shape elongation of embedded nanoparticles

    Science.gov (United States)

    Amekura, H.; Okubo, N.; Tsuya, D.; Ishikawa, N.

    2017-08-01

    Counterevidence is provided in the ion-hammering scenario as a driving force for the shape elongation of embedded nanoparticles (NPs) under swift heavy ion irradiation (SHII). Ion-induced compaction and the hammering, which are both induced in silica under SHII, dominate at low and high fluences, respectively, causing a crossover between them around a fluence of ˜4 × 1012 ions/cm2. Nevertheless, the shape elongation of NPs detected by the optical dichroism exhibits nearly linear dependence in a wide fluence range between ˜1 × 1011 and 2 × 1013 ions/cm2, indicating that the hammering does not play an important role.

  7. ASEAN-5 Passenger Car Industry Outlook: The Driving Forces, Opportunities and Challenges

    OpenAIRE

    Quek, Wu Kheng

    2010-01-01

    Global automotive industry is growing at an unprecedented speed in the past decade, primarily due to the strong and fastest growing demand from the Asian emerging economies. ASEAN-5 is an economic block with huge potential. It is an attractive alternative destination for business compare with other emerging economies. Total population is 420 million people and combined economic size of $1,355 billion in this region. ASEAN-5 countries are one of the major driving markets contributed to the rap...

  8. Measuring Risky Driving Behavior Using an mHealth Smartphone App: Development and Evaluation of gForce.

    Science.gov (United States)

    Freidlin, Raisa Z; Dave, Amisha D; Espey, Benjamin G; Stanley, Sean T; Garmendia, Marcial A; Pursley, Randall; Ehsani, Johnathon P; Simons-Morton, Bruce G; Pohida, Thomas J

    2018-04-19

    Naturalistic driving studies, designed to objectively assess driving behavior and outcomes, are conducted by equipping vehicles with dedicated instrumentation (eg, accelerometers, gyroscopes, Global Positioning System, and cameras) that provide continuous recording of acceleration, location, videos, and still images for eventual retrieval and analyses. However, this research is limited by several factors: the cost of equipment installation; management and storage of the large amounts of data collected; and data reduction, coding, and analyses. Modern smartphone technology includes accelerometers built into phones, and the vast, global proliferation of smartphones could provide a possible low-cost alternative for assessing kinematic risky driving. We evaluated an in-house developed iPhone app (gForce) for detecting elevated g-force events by comparing the iPhone linear acceleration measurements with corresponding acceleration measurements obtained with both a custom Android app and the in-vehicle miniDAS data acquisition system (DAS; Virginia Tech Transportation Institute). The iPhone and Android devices were dashboard-mounted in a vehicle equipped with the DAS instrumentation. The experimental protocol consisted of driving maneuvers on a test track, such as cornering, braking, and turning that were performed at different acceleration levels (ie, mild, moderate, or hard). The iPhone gForce app recorded linear acceleration (ie, gravity-corrected). The Android app recorded gravity-corrected and uncorrected acceleration measurements, and the DAS device recorded gravity-uncorrected acceleration measurements. Lateral and longitudinal acceleration measures were compared. The correlation coefficients between the iPhone and DAS acceleration measurements were slightly lower compared to the correlation coefficients between the Android and DAS, possibly due to the gravity correction on the iPhone. Averaging the correlation coefficients for all maneuvers, the longitudinal and

  9. Bilateral deficit in explosive force production is not caused by changes in agonist neural drive.

    Directory of Open Access Journals (Sweden)

    Matthew W Buckthorpe

    Full Text Available Bilateral deficit (BLD describes the phenomenon of a reduction in performance during synchronous bilateral (BL movements when compared to the sum of identical unilateral (UL movements. Despite a large body of research investigating BLD of maximal voluntary force (MVF there exist a paucity of research examining the BLD for explosive strength. Therefore, this study investigated the BLD in voluntary and electrically-evoked explosive isometric contractions of the knee extensors and assessed agonist and antagonist neuromuscular activation and measurement artefacts as potential mechanisms. Thirteen healthy untrained males performed a series of maximum and explosive voluntary contractions bilaterally (BL and unilaterally (UL. UL and BL evoked twitch and octet contractions were also elicited. Two separate load cells were used to measure MVF and explosive force at 50, 100 and 150 ms after force onset. Surface EMG amplitude was measured from three superficial agonists and an antagonist. Rate of force development (RFD and EMG were reported over consecutive 50 ms periods (0-50, 50-100 and 100-150 ms. Performance during UL contractions was compared to combined BL performance to measure BLD. Single limb performance during the BL contractions was assessed and potential measurement artefacts, including synchronisation of force onset from the two limbs, controlled for. MVF showed no BLD (P = 0.551, but there was a BLD for explosive force at 100 ms (11.2%, P = 0.007. There was a BLD in RFD 50-100 ms (14.9%, P = 0.004, but not for the other periods. Interestingly, there was a BLD in evoked force measures (6.3-9.0%, P<0.001. There was no difference in agonist or antagonist EMG for any condition (P≥0.233. Measurement artefacts contributed minimally to the observed BLD. The BLD in volitional explosive force found here could not be explained by measurement issues, or agonist and antagonist neuromuscular activation. The BLD in voluntary and evoked explosive force

  10. Polyphilic Interactions as Structural Driving Force Investigated by Molecular Dynamics Simulation (Project 7

    Directory of Open Access Journals (Sweden)

    Christopher Peschel

    2017-09-01

    Full Text Available We investigated the effect of fluorinated molecules on dipalmitoylphosphatidylcholine (DPPC bilayers by force-field molecular dynamics simulations. In the first step, we developed all-atom force-field parameters for additive molecules in membranes to enable an accurate description of those systems. On the basis of this force field, we performed extensive simulations of various bilayer systems containing different additives. The additive molecules were chosen to be of different size and shape, and they included small molecules such as perfluorinated alcohols, but also more complex molecules. From these simulations, we investigated the structural and dynamic effects of the additives on the membrane properties, as well as the behavior of the additive molecules themselves. Our results are in good agreement with other theoretical and experimental studies, and they contribute to a microscopic understanding of interactions, which might be used to specifically tune membrane properties by additives in the future.

  11. On the forces that drive and resist deformation of the south-central Mediterranean: a mechanical model study

    Science.gov (United States)

    Nijholt, Nicolai; Govers, Rob; Wortel, Rinus

    2018-04-01

    The geodynamics of the Mediterranean comprises a transitional setting in which slab rollback and plate convergence compete to shape the region. In the central Mediterranean, where the balance of driving and resisting forces changes continuously and rapidly since the Miocene, both kinematic and seismo-tectonic observations display a strong variation in deformation style and, therefore possibly, lithospheric forces. We aim to understand the current kinematics in southern Italy and Sicily in terms of lithospheric forces that cause them. The strong regional variation of geodetic velocities appears to prohibit such simple explanation. We use mechanical models to quantify the deformation resulting from large-scale Africa-Eurasia convergence, ESE retreat of the Calabrian subduction zone, pull by the Aegean slab, and regional variations in gravitational potential energy (topography). A key model element is the resistance to slip on major regional fault zones. We show that geodetic velocities, seismicity and sense of slip on regional faults can be understood to result from lithospheric forces. Our most important new finding is that regional variations in resistive tractions are required to fit the observations, with notably very low tractions on the Calabrian subduction contact, and a buildup towards a significant earthquake in the Calabrian fore-arc. We also find that the Calabrian net slab pull force is strongly reduced (compared to the value possible in view of the slab's dimensions) and that trench suction tractions are negligible. Such very small contributions to the present-day force balance in the south-central Mediterranean suggest that the Calabrian arc is now further transitioning towards a setting dominated by Africa-Eurasia plate convergence, whereas during the past 30 Myrs slab retreat continually was the dominant factor.

  12. Identifying the driving forces of urban expansion and its environmental impact in Jakarta-Bandung mega urban region

    Science.gov (United States)

    Pravitasari, A. E.; Rustiadi, E.; Mulya, S. P.; Setiawan, Y.; Fuadina, L. N.; Murtadho, A.

    2018-05-01

    The socio-economic development in Jakarta-Bandung Mega Urban Region (JBMUR) caused the increasing of urban expansion and led to a variety of environmental damage such as uncontrolled land use conversion and raising anthropogenic disaster. The objectives of this study are: (1) to identify the driving forces of urban expansion that occurs on JBMUR and (2) to analyze the environmental quality decline on JBMUR by producing time series spatial distribution map and spatial autocorrelation of floods and landslide as the proxy of anthropogenic disaster. The driving forces of urban expansion in this study were identified by employing Geographically Weighted Regression (GWR) model using 6 (six) independent variables, namely: population density, percentage of agricultural land, distance to the center of capital city/municipality, percentage of household who works in agricultural sector, distance to the provincial road, and distance to the local road. The GWR results showed that local demographic, social and economic factors including distance to the road spatially affect urban expansion in JBMUR. The time series spatial distribution map of floods and landslide event showed the spatial cluster of anthropogenic disaster in some areas. Through Local Moran Index, we found that environmental damage in one location has a significant impact on the condition of its surrounding area.

  13. Land use changes and its driving forces in hilly ecological restoration area based on gis and rs of northern china

    Science.gov (United States)

    Gao, Peng; Niu, Xiang; Wang, Bing; Zheng, Yunlong

    2015-01-01

    Land use change is one of the important aspects of the regional ecological restoration research. With remote sensing (RS) image in 2003, 2007 and 2012, using geographic information system (GIS) technologies, the land use pattern changes in Yimeng Mountain ecological restoration area in China and its driving force factors were studied. Results showed that: (1) Cultivated land constituted the largest area during 10 years, and followed by forest land and grass land; cultivated land and unused land were reduced by 28.43% and 44.32%, whereas forest land, water area and land for water facilities and others were increased. (2) During 2003–2007, forest land change showed the largest, followed by unused land and grass land; however, during 2008–2012, water area and land for water facilities change showed the largest, followed by grass land and unused land. (3) Land use degree was above the average level, it was in the developing period during 2003–2007 and in the degenerating period during 2008–2012. (4) Ecological Restoration Projects can greatly change the micro topography, increase vegetation coverage, and then induce significant changes in the land use distribution, which were the main driving force factors of the land use pattern change in the ecological restoration area. PMID:26047160

  14. Exciplexes versus Loose Ion Pairs: How Does the Driving Force Impact the Initial Product Ratio of Photoinduced Charge Separation Reactions?

    Science.gov (United States)

    2014-01-01

    Many donor–acceptor systems can undergo a photoinduced charge separation reaction, yielding loose ion pairs (LIPs). LIPs can be formed either directly via (distant) electron transfer (ET) or indirectly via the dissociation of an initially formed exciplex or tight ion pair. Establishing the prevalence of one of the reaction pathways is challenging because differentiating initially formed exciplexes from LIPs is difficult due to similar spectroscopic footprints. Hence, no comprehensive reaction model has been established for moderately polar solvents. Here, we employ an approach based on the time-resolved magnetic field effect (MFE) of the delayed exciplex luminescence to distinguish the two reaction channels. We focus on the effects of the driving force of ET and the solvent permittivity. We show that, surprisingly, the exciplex channel is significant even for an exergonic ET system with a free energy of ET of −0.58 eV and for the most polar solutions studied (butyronitrile). Our findings demonstrate that exciplexes play a crucial role even in polar solvents and at moderate driving forces, contrary to what is usually assumed. PMID:25243054

  15. Relative importance of driving force and electrostatic interactions in the reduction of multihaem cytochromes by small molecules.

    Science.gov (United States)

    Quintas, Pedro O; Cepeda, Andreia P; Borges, Nuno; Catarino, Teresa; Turner, David L

    2013-06-01

    Multihaem cytochromes are essential to the energetics of organisms capable of bioremediation and energy production. The haems in several of these cytochromes have been discriminated thermodynamically and their individual rates of reduction by small electron donors were characterized. The kinetic characterization of individual haems used the Marcus theory of electron transfer and assumed that the rates of reduction of each haem by sodium dithionite depend only on the driving force, while electrostatic interactions were neglected. To determine the relative importance of these factors in controlling the rates, we studied the effect of ionic strength on the redox potential and the rate of reduction by dithionite of native Methylophilus methylotrophus cytochrome c″ and three mutants at different pH values. We found that the main factor determining the rate is the driving force and that Marcus theory describes this satisfactorily. This validates the method of the simultaneous fitting of kinetic and thermodynamic data in multihaem cytochromes and opens the way for further investigation into the mechanisms of these proteins. Copyright © 2013 Elsevier B.V. All rights reserved.

  16. Inhibiting and driving forces for the digitalization of security systems: security officers’ view on the issue

    OpenAIRE

    Lahtinen, Markus

    2007-01-01

    This memo reports on factors that drive and inhibit the digitalization of security systems. The reported factors are as follows: Technology-push factors • Need to lower costs on the end-user side, i.e. replacing labour with technology • Perceived convenience and ease-of-use of digital systems • Digital products can be connected to the current enterprise network; enabling an expanding set of security features • Firms holding the IP-capability (IP=Internet Protocol) and not h...

  17. External and internal influences as driving forces and/or stumbling ...

    African Journals Online (AJOL)

    The development of national and institutional quality assurance and management systems is often forced (rightfully or wrongly) into a specific direction by external and internal environmental influences. In South Africa such influences play a major role in both the national higher education policy developments and the ...

  18. TSC [Tokamak Simulation Code] disruption scenarios and CIT [Compact Ignition Tokamak] vacuum vessel force evolution

    International Nuclear Information System (INIS)

    Sayer, R.O.; Peng, Y.K.M.; Strickler, D.J.; Jardin, S.C.

    1990-01-01

    The Tokamak Simulation Code and the TWIR postprocessor code have been used to develop credible plasma disruption scenarios for the Compact Ignition Tokamak (CIT) in order to predict the evolution of forces on CIT conducting structures and to provide results required for detailed structural design analysis. The extreme values of net radial and vertical vacuum vessel (VV) forces were found to be F R =-12.0 MN/rad and F Z =-3.0 MN/rad, respectively, for the CIT 2.1-m, 11-MA design. Net VV force evolution was found to be altered significantly by two mechanisms not noted previously. The first, due to poloidal VV currents arising from increased plasma paramagnetism during thermal quench, reduces the magnitude of the extreme F R by 15-50% and modifies the distribution of forces substantially. The second effect is that slower plasma current decay rates give more severe net vertical VV loads because the current decay occurs when the plasma has moved farther from midplane than is the case for faster decay rates. 7 refs., 9 figs., 1 tab

  19. Evaluation on driving force of natural circulation in downcomer for passive residual heat removal system in JAERI passive safety reactor JPSR

    International Nuclear Information System (INIS)

    Kunii, Katsuhiko; Iwamura, Takamichi; Murao, Yoshio

    1997-01-01

    The driving-force of the natural circulation in the residual heat removal (RHR) system for the JPSR (JAERI Passive Safety Reactor) is given as a gravity force of the density difference between hotter coolant in core and upper plenum and cooler coolant in downcomer. The amount of density difference and time to achieve the enough density difference for the RHR system change directly dependent on the thermal fluid flow pattern in downcomer of annulus flow pass. The purposes of the present study are to investigate the possibilities of the followings by evaluating the three-dimensional thermal fluid flow in downcomer by numerical analysis using the STREAM code; 1) promotion of making the flow pattern uniform in downcomer by installing a baffle, 2) achievement of an enough driving-force of the natural circulation, 3) validity of one-point assumption, that is, complete mixing down-flow assumption for the three-dimensional thermal fluid flow in downcomer to evaluate the function of the passive RHR system. The following conclusions were obtained: (1) The effect of baffle on the thermal fluid flow and driving-force is little, (2) The driving-force required for natural circulation cooling can be obtained in wide range of inlet velocity even if the flow is multi-dimensional, (3) Both in initial transient stage and in steady-state, the one-point assumption can be applied to evaluate the driving-force of natural circulation in the passive RHR system. (author)

  20. Herbivory as an important selective force in the evolution of floral traits and pollinator shifts

    Science.gov (United States)

    Overson, Rick P.; Raguso, Robert A.; Skogen, Krissa A.

    2017-01-01

    Abstract Floral trait evolution is frequently attributed to pollinator-mediated selection but herbivores can play a key role in shaping plant reproductive biology. Here we examine the role of florivores in driving floral trait evolution and pollinator shifts in a recently radiated clade of flowering plants, Oenothera sect. Calylophus. We compare florivory by a specialist, internal feeder, Mompha, on closely related hawkmoth- and bee-pollinated species and document variation in damage based on floral traits within sites, species and among species. Our results show that flowers with longer floral tubes and decreased floral flare have increased Mompha damage. Bee-pollinated flowers, which have substantially smaller floral tubes, experience on average 13% less Mompha florivory than do hawkmoth-pollinated flowers. The positive association between tube length and Mompha damage is evident even within sites of some species, suggesting that Mompha can drive trait differentiation at microevolutionary scales. Given that there are at least two independent shifts from hawkmoth to bee pollination in this clade, florivore-mediated selection on floral traits may have played an important role in facilitating morphological changes associated with transitions from hawkmoth to bee pollination. PMID:28011456

  1. Dynamics of aeolian desertification and its driving forces in the Horqin Sandy Land, Northern China.

    Science.gov (United States)

    Duan, Han-chen; Wang, Tao; Xue, Xian; Liu, Shu-lin; Guo, Jian

    2014-10-01

    Aeolian desertification is one of the most serious environmental and socioeconomic problems in arid, semi-arid, and dry subhumid zones. Understanding desertification processes and causes is important to provide reasonable and effective control measures for preventing desertification. With satellite remote sensing images as data source to assess the temporal and spatial dynamics of desertification from 1975 to 2010 in the Horqin Sandy Land, dynamic changes of aeolian desertification were detected using the human-machine interactive interpretation method. The driving factors of local desertification were analyzed based on natural and socioeconomic data. The results show that aeolian desertified land in the study area covered 30,199 km(2) in 2010, accounting for 24.1% of the study area. The total area of aeolian desertified land obviously expanded from 30,884 km(2) in 1975 to 32,071 km(2) in 1990, and gradually decreased to 30,199 km(2) in 2010; aeolian desertified land represented an increasing trend firstly and then decreased. During the past 35 years, the gravity centers of desertified lands that are classified as extremely severe and severe generally migrated to the northeast, whereas those that are moderate and slight migrated to the northwest. The migration distance of severely desertified land was the largest, which indicated the southern desertified lands were improved during the last few decades. In addition, the climatic variation in the past 35 years has been favorable to desertification in the Horqin Sandy Land. Aeolian desertified land rapidly expanded from 1975 to 1990 under the combined effects of climate changes and unreasonable human activities. After the 1990s, the main driving factors responsible for the decrease in desertification were positive human activities, such as the series of antidesertification and ecological restoration projects.

  2. Spatial Patterns and Driving Forces of Greenhouse Land Change in Shouguang City, China

    Directory of Open Access Journals (Sweden)

    Bohua Yu

    2017-03-01

    Full Text Available As an important facet of modern agricultural development, greenhouses satisfy ever-increasing demands for agricultural production and, therefore, constitute a growing proportion of global agriculture. However, just a handful of countries regularly collect statistics on the land cover of greenhouse infrastructure. Even when collected, these data cannot provide the detailed spatial information required for environmental risk assessment. It is, therefore, important to map spatial changes in greenhouse land cover using remote sensing (RS approaches to determine the underlying factors driving these changes. In this paper, we apply a support vector machine (SVM algorithm to identify greenhouse land cover in Shouguang City, China. Enhanced thematic mapper (ETM images were selected as the data source for land use classification in this study as they can be freely acquired and offer the necessary spatial resolution. We then used a binary logistic regression model to quantitatively discern the mechanisms underlying changes in greenhouse land cover. The results of this study show that greenhouse land cover in Shouguang increased by 50.51% between 2000 and 2015, and that 90.39% of this expansion took place between 2010 and 2015. Elevation, slope, precipitation, and the distance to the nearest rural settlements and coastline are all significant factors driving expansion in greenhouse land cover, while distance to the nearest urban areas, rivers, roads, railways, and coastline have contributed to contractions in this land use type. Our research provided a practical approach to allow the detection of changes in greenhouse land cover in the countries with using free or low-cost satellite images.

  3. Driving forces of rapid CO2 emissions growth: A case of Korea

    International Nuclear Information System (INIS)

    Kim, Yong-Gun; Yoo, Jonghyun; Oh, Wankeun

    2015-01-01

    This study aims to investigate Korea's final demand structure and its impacts on CO 2 emissions in order to reduce CO 2 emissions and develop environmental policy directions. Based on the environmentally extended input–output model, this study adopts a two-step approach: (1) to estimate the embodied emissions and their intensities for 393 sectors induced by final demand; and (2) to calculate the driving factors of emission growth between 2003 and 2011 and then evaluate the result by using Structural Decomposition Analysis (SDA). The findings of this study demonstrate that the impact of composition change in export with less embodied emission intensities tends to offset the increase in CO 2 emission by the export scale growth. The relatively low residential electricity price has resulted in the rapid growth of household electricity consumption and significantly contributed to emissions growth. The result of SDA indicates that Korea's final demand behavior yielded high carbonization over the same period. The findings suggest that Korean government should promote exports in industries with less embedded CO 2 in order to protect environments. In addition, emission information of each product and service should be provided for consumers to change their purchase patterns towards contributing to low carbon emissions as active players. -- Highlights: •We investigate Korea's final demand structure and its contribution to CO 2 emissions. •Using SDA, we evaluate the driving factors of emission growth from 2003 to 2011. •Exports play a critical role in Korea's CO 2 emissions growth. •The relatively low residential electricity price has contributed to emission growth. •Korea's final demand behavior yielded high carbonization over the same period

  4. Directional Selection from Host Plants Is a Major Force Driving Host Specificity in Magnaporthe Species.

    Science.gov (United States)

    Zhong, Zhenhui; Norvienyeku, Justice; Chen, Meilian; Bao, Jiandong; Lin, Lianyu; Chen, Liqiong; Lin, Yahong; Wu, Xiaoxian; Cai, Zena; Zhang, Qi; Lin, Xiaoye; Hong, Yonghe; Huang, Jun; Xu, Linghong; Zhang, Honghong; Chen, Long; Tang, Wei; Zheng, Huakun; Chen, Xiaofeng; Wang, Yanli; Lian, Bi; Zhang, Liangsheng; Tang, Haibao; Lu, Guodong; Ebbole, Daniel J; Wang, Baohua; Wang, Zonghua

    2016-05-06

    One major threat to global food security that requires immediate attention, is the increasing incidence of host shift and host expansion in growing number of pathogenic fungi and emergence of new pathogens. The threat is more alarming because, yield quality and quantity improvement efforts are encouraging the cultivation of uniform plants with low genetic diversity that are increasingly susceptible to emerging pathogens. However, the influence of host genome differentiation on pathogen genome differentiation and its contribution to emergence and adaptability is still obscure. Here, we compared genome sequence of 6 isolates of Magnaporthe species obtained from three different host plants. We demonstrated the evolutionary relationship between Magnaporthe species and the influence of host differentiation on pathogens. Phylogenetic analysis showed that evolution of pathogen directly corresponds with host divergence, suggesting that host-pathogen interaction has led to co-evolution. Furthermore, we identified an asymmetric selection pressure on Magnaporthe species. Oryza sativa-infecting isolates showed higher directional selection from host and subsequently tends to lower the genetic diversity in its genome. We concluded that, frequent gene loss or gain, new transposon acquisition and sequence divergence are host adaptability mechanisms for Magnaporthe species, and this coevolution processes is greatly driven by directional selection from host plants.

  5. On the Evolution of Pulsatile Flow Subject to a Transverse Impulse Body Force

    Science.gov (United States)

    di Labbio, Giuseppe; Keshavarz-Motamed, Zahra; Kadem, Lyes

    2014-11-01

    In the event of an unexpected abrupt traffic stop or car accident, automotive passengers will experience an abrupt body deceleration. This may lead to tearing or dissection of the aortic wall known as Blunt Traumatic Aortic Rupture (BTAR). BTAR is the second leading cause of death in automotive accidents and, although quite frequent, the mechanisms leading to BTAR are still not clearly identified, particularly the contribution of the flow field. As such, this work is intended to provide a fundamental framework for the investigation of the flow contribution to BTAR. In this fundamental study, pulsatile flow in a three-dimensional, straight pipe of circular cross-section is subjected to a unidirectional, transverse, impulse body force applied on a strictly bounded volume of fluid. These models were simulated using the Computational Fluid Dynamics (CFD) software FLUENT. The evolution of fluid field characteristics was investigated during and after the application of the force. The application of the force significantly modified the flow field. The force induces a transverse pressure gradient causing the development of secondary flow structures that dissipate the energy added by the acceleration. Once the force ceases to act, these structures are carried downstream and gradually dissipate their excess energy.

  6. Evolution of strategies and competition in the international airline industry: a practical analysis using porter's competitive forces model

    OpenAIRE

    Zannoni, Niccolò

    2013-01-01

    This master thesis describes the evolution of the competition and strategies in the international airline industry. It studies the industry before and after deregulation, using the competitive forces model.

  7. Prerequisites and driving forces behind an extended working life among older workers.

    Science.gov (United States)

    Hovbrandt, Pia; Håkansson, Carita; Albin, Maria; Carlsson, Gunilla; Nilsson, Kerstin

    2017-11-28

    Reforms are changing pension systems in many European countries, in order to both restrict early retirement and force people to extend their working life. From occupational therapy and occupational science perspectives, studies focusing on aspects of working life that motivate the older worker is urgent. The aim was to describe incentives behind an extended working life among people over age 65. Focus group methodology was used, with participants ages 66-71, from varying work fields: construction and technical companies and the municipal elderly care sector. Work was considered important and valuable to the degree of how challenging work was, the possibilities for inclusion in a team of colleagues and the chances for better personal finances. Amongst all, the participants expressed a feeling of a strengthened identity by being challenged and having the opportunity to manage working tasks. The finding showed the actual reasons behind an extended working life among older workers. However, a risk of rising social inequity may appear with increased working life if older people are forced to extend their working life due to a difficult financial situation as a pensioner. A variety of retirement options and initiatives in order to support older workers are justified.

  8. The organization and evolution of the Responder satellite in species of the Drosophila melanogaster group: dynamic evolution of a target of meiotic drive.

    Science.gov (United States)

    Larracuente, Amanda M

    2014-11-25

    Satellite DNA can make up a substantial fraction of eukaryotic genomes and has roles in genome structure and chromosome segregation. The rapid evolution of satellite DNA can contribute to genomic instability and genetic incompatibilities between species. Despite its ubiquity and its contribution to genome evolution, we currently know little about the dynamics of satellite DNA evolution. The Responder (Rsp) satellite DNA family is found in the pericentric heterochromatin of chromosome 2 of Drosophila melanogaster. Rsp is well-known for being the target of Segregation Distorter (SD)- an autosomal meiotic drive system in D. melanogaster. I present an evolutionary genetic analysis of the Rsp family of repeats in D. melanogaster and its closely-related species in the melanogaster group (D. simulans, D. sechellia, D. mauritiana, D. erecta, and D. yakuba) using a combination of available BAC sequences, whole genome shotgun Sanger reads, Illumina short read deep sequencing, and fluorescence in situ hybridization. I show that Rsp repeats have euchromatic locations throughout the D. melanogaster genome, that Rsp arrays show evidence for concerted evolution, and that Rsp repeats exist outside of D. melanogaster, in the melanogaster group. The repeats in these species are considerably diverged at the sequence level compared to D. melanogaster, and have a strikingly different genomic distribution, even between closely-related sister taxa. The genomic organization of the Rsp repeat in the D. melanogaster genome is complex-it exists of large blocks of tandem repeats in the heterochromatin and small blocks of tandem repeats in the euchromatin. My discovery of heterochromatic Rsp-like sequences outside of D. melanogaster suggests that SD evolved after its target satellite and that the evolution of the Rsp satellite family is highly dynamic over a short evolutionary time scale (<240,000 years).

  9. Geological and climatic forces driving speciation in the continentally distributed trilling chorus frogs (Pseudacris).

    Science.gov (United States)

    Lemmon, Emily Moriarty; Lemmon, Alan R; Cannatella, David C

    2007-09-01

    Tertiary geological events and Quaternary climatic fluctuations have been proposed as important factors of speciation in the North American flora and fauna. Few studies, however, have rigorously tested hypotheses regarding the specific factors driving divergence of taxa. Here, we test explicit speciation hypotheses by correlating geologic events with divergence times among species in the continentally distributed trilling chorus frogs (Pseudacris). In particular, we ask whether marine inundation of the Mississippi Embayment, uplift of the Appalachian Mountains, or modification of the ancient Teays-Mahomet River system contributed to speciation. To examine the plausibility of ancient rivers causing divergence, we tested whether modern river systems inhibit gene flow. Additionally, we compared the effects of Quaternary climatic factors (glaciation and aridification) on levels of genetic variation. Divergence time estimates using penalized likelihood and coalescent approaches indicate that the major lineages of chorus frogs diversified during the Tertiary, and also exclude Quaternary climate change as a factor in speciation of chorus frogs. We show the first evidence that inundation of the Mississippi Embayment contributed to speciation. We reject the hypotheses that Cenozoic uplift of the Appalachians and that diversion of the Teays-Mahomet River contributed to speciation in this clade. We find that by reducing gene flow, rivers have the potential to cause divergence of lineages. Finally, we demonstrate that populations in areas affected by Quaternary glaciation and aridification have reduced levels of genetic variation compared to those from more equable regions, suggesting recent colonization.

  10. Research Problems Associated with Limiting the Applied Force in Vibration Tests and Conducting Base-Drive Modal Vibration Tests

    Science.gov (United States)

    Scharton, Terry D.

    1995-01-01

    The intent of this paper is to make a case for developing and conducting vibration tests which are both realistic and practical (a question of tailoring versus standards). Tests are essential for finding things overlooked in the analyses. The best test is often the most realistic test which can be conducted within the cost and budget constraints. Some standards are essential, but the author believes more in the individual's ingenuity to solve a specific problem than in the application of standards which reduce problems (and technology) to their lowest common denominator. Force limited vibration tests and base-drive modal tests are two examples of realistic, but practical testing approaches. Since both of these approaches are relatively new, a number of interesting research problems exist, and these are emphasized herein.

  11. Why the short face? Developmental disintegration of the neurocranium drives convergent evolution in neotropical electric fishes.

    Science.gov (United States)

    Evans, Kory M; Waltz, Brandon; Tagliacollo, Victor; Chakrabarty, Prosanta; Albert, James S

    2017-03-01

    Convergent evolution is widely viewed as strong evidence for the influence of natural selection on the origin of phenotypic design. However, the emerging evo-devo synthesis has highlighted other processes that may bias and direct phenotypic evolution in the presence of environmental and genetic variation. Developmental biases on the production of phenotypic variation may channel the evolution of convergent forms by limiting the range of phenotypes produced during ontogeny. Here, we study the evolution and convergence of brachycephalic and dolichocephalic skull shapes among 133 species of Neotropical electric fishes (Gymnotiformes: Teleostei) and identify potential developmental biases on phenotypic evolution. We plot the ontogenetic trajectories of neurocranial phenotypes in 17 species and document developmental modularity between the face and braincase regions of the skull. We recover a significant relationship between developmental covariation and relative skull length and a significant relationship between developmental covariation and ontogenetic disparity. We demonstrate that modularity and integration bias the production of phenotypes along the brachycephalic and dolichocephalic skull axis and contribute to multiple, independent evolutionary transformations to highly brachycephalic and dolichocephalic skull morphologies.

  12. Seasonal changes and driving forces of inflow and outflow through the Bohai Strait

    Science.gov (United States)

    Zhang, Zhixin; Qiao, Fangli; Guo, Jingsong; Guo, Binghuo

    2018-02-01

    This work focuses on analyzing seasonal variation of inflow and outflow through the Bohai Strait that greatly affect the marine environment in the Bohai Sea, using observational data including sea bed mounted acoustic Doppler current profiler currents, CTD salinity data on deck, sea level anomalies of coastal tide gauge stations, and climatological monthly sea level anomalies from Archiving, Validation and Interpretation of Satellite Oceanographic data. Our results show three patterns of outflow and inflow through the Bohai Strait. The first is such that outflow and inflow occur respectively in the southern and northern parts of the strait, as in the traditional understanding. Our results suggest that this pattern occurs only in autumn and winter. Beginning in late September, Ekman currents driven by the northwesterly monsoon carry Bohai Sea water that piles up in the southern part of that sea and then exits eastward to the Yellow Sea. In this process, the pressure and current fields are continuously adjusted, until a quasi balance state between wind stress, Coriolis force and pressure gradient force is reached in winter. Inflow with a compensating property through the northern channel is close to the outflow through the southern channel in winter. The second pattern is a single inflow in spring, and the current and pressure fields are in adjustment. In early spring, the northwesterly monsoon ceases, Yellow Sea water enters the Bohai Sea under the pressure gradient force. With southeasterly monsoon establishment and strengthening, northern Yellow Sea water continually flows into the Bohai Sea and causes sea level rise northward. In the third pattern, outflow is much greater than inflow in summer. The currents run eastward in the central Bohai Sea and then enter the northern Yellow Sea through the northern channel and upper layer of the southern channel, while a westward current with a compensating property enters via the lower layer of the southern channel. Larger

  13. Analyzing driving forces behind changes in energy vulnerability of Spanish electricity generation through a Divisia index-based method

    International Nuclear Information System (INIS)

    Fernández González, P.; Moreno, B.

    2015-01-01

    Highlights: • We propose and develop the LMDI approach to factorize changes in electricity bill vulnerability. • Spanish vulnerability (1995–2011) markedly grew mainly by increasing gas dependence. • Fuel price increase and growing importance of electricity damage energy security. • Energy intensity advances & fuel diversification: insufficient to drive vulnerability. • Main recommendation: enhance internal energy market and common external EU strategy. - Abstract: High energy dependence on fossil raises vulnerability concerns about security of supply and energy cost. This research examines the impact of high dependence of imported fuels for power generation in Spain through the quantification and analysis of the driving forces behind the change in its electricity bill. Following logarithmic mean Divisia indexes approach, we present and perform a new method that enables a complete decomposition of changes in electricity vulnerability into contributions from several drivers. In fact, we identify five predefined factors behind the variations in vulnerability in Spain during the 1998–2011 period: fuel price, average heat rate, fuel dependence, degree of electricity importance and energy intensity. The application of this approach reveals a significant increase in Spanish vulnerability in the last two decades, promoted by increments in fuel price and importance of electricity over the primary energy consumption, but especially by increasing fuel dependence (particularly gas dependence). Therefore, findings mainly advocate for those strategies aimed at reducing Spanish energy dependence. Also those improving thermal efficiency and energy intensity are indicated

  14. Tendency to occupy a statistically dominant spatial state of the flow as a driving force for turbulent transition.

    Science.gov (United States)

    Chekmarev, Sergei F

    2013-03-01

    The transition from laminar to turbulent fluid motion occurring at large Reynolds numbers is generally associated with the instability of the laminar flow. On the other hand, since the turbulent flow characteristically appears in the form of spatially localized structures (e.g., eddies) filling the flow field, a tendency to occupy such a structured state of the flow cannot be ruled out as a driving force for turbulent transition. To examine this possibility, we propose a simple analytical model that treats the flow as a collection of localized spatial structures, each of which consists of elementary cells in which the behavior of the particles (atoms or molecules) is uncorrelated. This allows us to introduce the Reynolds number, associating it with the ratio between the total phase volume for the system and that for the elementary cell. Using the principle of maximum entropy to calculate the most probable size distribution of the localized structures, we show that as the Reynolds number increases, the elementary cells group into the localized structures, which successfully explains turbulent transition and some other general properties of turbulent flows. An important feature of the present model is that a bridge between the spatial-statistical description of the flow and hydrodynamic equations is established. We show that the basic assumptions underlying the model, i.e., that the particles are indistinguishable and elementary volumes of phase space exist in which the state of the particles is uncertain, are involved in the derivation of the Navier-Stokes equation. Taking into account that the model captures essential features of turbulent flows, this suggests that the driving force for the turbulent transition is basically the same as in the present model, i.e., the tendency of the system to occupy a statistically dominant state plays a key role. The instability of the flow at high Reynolds numbers can then be a mechanism to initiate structural rearrangement of

  15. The driving forces for nitrogen and phosphorus flows in the food chain of china, 1980 to 2010.

    Science.gov (United States)

    Hou, Y; Ma, L; Gao, Z L; Wang, F H; Sims, J T; Ma, W Q; Zhang, F S

    2013-07-01

    Nitrogen (N) and phosphorus (P) use and losses in China's food chain have accelerated in the past three decades, driven by population growth, rapid urbanization, dietary transition, and changing nutrient management practice. There has been little detailed quantitative analysis of the relative magnitude of these driving forces throughout this period. Therefore, we analyzed changes in N and P flows and key drivers behind changes in the food (production and consumption) chain at the national scale from 1980 to 2010. Food (N and P) consumption increased by about fivefold in urban settings over this period but has decreased in rural settings since the 1990s. For urban settings, the integrated driving forces for increased food consumption were population growth, which accounted for ∼60%, and changing urban diets toward a greater emphasis on the consumption of animal products. Nutrient inputs and losses in crop and animal productions have continuously increased from 1980 to 2010, but the rates of decadal increase were greatly different. Increased total inputs and losses in crop production were primarily driven by increased crop production for food demand (68-96%) in the 1980s but were likely offset in the 2000s by improved nutrient management practices, as evidenced by decreased total inputs to and losses from cropland for harvesting per nutrient in crop. The contributions of animal production to total N and P losses to waters from the food chain increased by 34 and 60% from 1980 to 2010. These increases were caused mainly by decreased ratios of manure returned to cropland. Our study highlights a larger impact of changing nutrient management practice than population growth on elevated nutrient flows in China's food chain. Copyright © by the American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America, Inc.

  16. Transitions in Land Use Architecture under Multiple Human Driving Forces in a Semi-Arid Zone

    Directory of Open Access Journals (Sweden)

    Issa Ouedraogo

    2015-07-01

    Full Text Available The present study aimed to detect the main shifts in land-use architecture and assess the factors behind the changes in typical tropical semi-arid land in Burkina Faso. Three sets of time-series LANDSAT data over a 23-year period were used to detect land use changes and their underpinning drivers in multifunctional but vulnerable ecologies. Group discussions in selected villages were organized for mapping output interpretation and collection of essential drivers of change as perceived by local populations. Results revealed profound changes and transitions during the study period. During the last decade, shrub and wood savannahs exhibited high net changes (39% and −37% respectively with a weak net positive change for cropland (only 2%, while cropland and shrub savannah exhibited high swap (8% and 16%. This suggests that the area of cropland remained almost unchanged but was subject to relocation, wood savannah decreased drastically, and shrub savannah increased exponentially. Cropland exhibited a null net persistence while shrub and wood savannahs exhibited positive and negative net persistence (1.91 and −10.24, respectively, indicating that there is movement toward agricultural intensification and wood savannah tended to disappear to the benefit of shrub savannah. Local people are aware of the changes that have occurred and support the idea that illegal wood cutting and farming are inappropriate farming practices associated with immigration; absence of alternative cash generation sources, overgrazing and increasing demand for wood energy are driving the changes in their ecosystems. Policies that integrate restoration and conservation of natural ecosystems and promote sustainable agroforestry practices in the study zone are highly recommended.

  17. Environmental heterogeneity drives within-host diversification and evolution of Pseudomonas aeruginosa

    DEFF Research Database (Denmark)

    Markussen, Trine; Marvig, Rasmus Lykke; Gómez Lozano, María

    2014-01-01

    Within-host pathogen evolution and diversification during the course of chronic infections is of importance in relation to therapeutic intervention strategies, yet our understanding of these processes is limited. Here, we investigate intraclonal population diversity in P. aeruginosa during chronic...

  18. Competing feedbacks drive state transitions during initial catchment evolution: Examples from post-mining landscape and ecosystems evolution

    Science.gov (United States)

    Hinz, Christoph; Wolfgang, Schaaf; Werner, Gerwin

    2014-05-01

    Within the context of severely disturbed landscapes with little or no ecological memory, such as post-mining landscapes, we propose a simple framework that explains the catchment evolution as a result of competing feedbacks influenced by the initial conditions and the atmospheric drivers such as rainfall intermittency and intensity. The first stage of the evolution is dominated by abiotic feedbacks triggered by rainfall and subsequent fluid flow causing particle mobilisation on the surface and in the subsurface leading to flow concentration or in some instances to densification of surface and subsurface substrates. Subsequently, abiotic-biotic feedbacks start to compete in the sense that biological activity generally stabilizes substrate by preventing particle mobilisation and hence contribute to converting the substrate to a habitat. We suggest that these competing feedbacks may generate alternative stable states in particular under semi-arid and arid climatic conditions, while in temperate often energy limited environments biological process "outcompete" abiotic processes leading to a stable state, in particular from the water balance point of view for comparable geomorphic situations. To illustrate this framework, we provide examples from post-mining landscapes, in which soil, water and vegetation was monitored. In case of arid regions in Australia, we provide evidence that the initial conditions of a mine waste disposal "locked" the system into a state that was limited by water and nutrient storage capacity while at the same time it was stable from a geomorphic point of view for the observation period. The cause of the system to be locked in, is the very high hydraulic conductivity of the substrate, that has not undergone any changes during the first years. In contrast to this case study, we illustrate how this framework explains the evolution of an artificial catchment (Hühnerwasser Catchment) in Lusatia (150 km southeast of Berlin, Germany). During the

  19. Correlated evolution of male and female reproductive traits drive a cascading effect of reinforcement in Drosophila yakuba

    Science.gov (United States)

    Comeault, Aaron A.; Venkat, Aarti; Matute, Daniel R.

    2016-01-01

    Selection against maladaptive hybridization can drive the evolution of reproductive isolation in a process called reinforcement. While the importance of reinforcement in evolution has been historically debated, many examples now exist. Despite these examples, we typically lack a detailed understanding of the mechanisms limiting the spread of reinforced phenotypes throughout a species' range. Here we address this issue in the fruit fly Drosophila yakuba, a species that hybridizes with its sister species D. santomea and is undergoing reinforcement in a well-defined hybrid zone on the island of São Tomé. Within this region, female D. yakuba show increased postmating-prezygotic (gametic) isolation towards D. santomea when compared with females from allopatric populations. We use a combination of natural collections, fertility assays, and experimental evolution to understand why reinforced gametic isolation in D. yakuba is confined to this hybrid zone. We show that, among other traits, D. yakuba males from sympatric populations sire fewer progeny than allopatric males when mated to allopatric D. yakuba females. Our results provide a novel example of reinforcement acting on a postmating-prezygotic trait in males, resulting in a cascade of reproductive isolation among conspecific populations. PMID:27440664

  20. Sequential actin-based pushing forces drive meiosis I chromosome migration and symmetry breaking in oocytes

    Science.gov (United States)

    Yi, Kexi; Rubinstein, Boris; Unruh, Jay R.; Guo, Fengli; Slaughter, Brian D.

    2013-01-01

    Polar body extrusion during oocyte maturation is critically dependent on asymmetric positioning of the meiotic spindle, which is established through migration of the meiosis I (MI) spindle/chromosomes from the oocyte interior to a subcortical location. In this study, we show that MI chromosome migration is biphasic and driven by consecutive actin-based pushing forces regulated by two actin nucleators, Fmn2, a formin family protein, and the Arp2/3 complex. Fmn2 was recruited to endoplasmic reticulum structures surrounding the MI spindle, where it nucleated actin filaments to initiate an initially slow and poorly directed motion of the spindle away from the cell center. A fast and highly directed second migration phase was driven by actin-mediated cytoplasmic streaming and occurred as the chromosomes reach a sufficient proximity to the cortex to activate the Arp2/3 complex. We propose that decisive symmetry breaking in mouse oocytes results from Fmn2-mediated perturbation of spindle position and the positive feedback loop between chromosome signal-induced Arp2/3 activation and Arp2/3-orchestrated cytoplasmic streaming that transports the chromosomes. PMID:23439682

  1. Thermodynamic Description of Synergy in Solvent Extraction: II Thermodynamic Balance of Driving Forces Implied in Synergistic Extraction.

    Science.gov (United States)

    Rey, J; Bley, M; Dufrêche, J-F; Gourdin, S; Pellet-Rostaing, S; Zemb, T; Dourdain, S

    2017-11-21

    In the second part of this study, we analyze the free energy of transfer in the case of synergistic solvent extraction. This free energy of the transfer of an ion in dynamic equilibrium between two coexisting phases is decomposed into four driving forces combining long-range interactions with the classical complexation free energy associated with the nearest neighbors. We demonstrate how the organometallic complexation is counterbalanced by the cost in free energy related to structural change on the colloidal scale in the solvent phase. These molecular forces of synergistic extraction are driven not only by the entropic term associated with the tight packing of electrolytes in the solvent and by the free energy cost of coextracting water toward the hydrophilic core of the reverse aggregates present but also by the entropic costs in the formation of the reverse aggregate and by the interfacial bending energy of the extractant molecules packed around the extracted species. Considering the sum of the terms, we can rationalize the synergy observed, which cannot be explained by classical extraction modeling. We show an industrial synergistic mixture combining an amide and a phosphate complexing site, where the most efficient/selective mixture is observed for a minimal bending energy and maximal complexation energy.

  2. Recombination Is a Major Driving Force of Genetic Diversity in the Anaplasmataceae Ehrlichia ruminantium.

    Science.gov (United States)

    Cangi, Nídia; Gordon, Jonathan L; Bournez, Laure; Pinarello, Valérie; Aprelon, Rosalie; Huber, Karine; Lefrançois, Thierry; Neves, Luís; Meyer, Damien F; Vachiéry, Nathalie

    2016-01-01

    The disease, Heartwater, caused by the Anaplasmataceae E. ruminantium , represents a major problem for tropical livestock and wild ruminants. Up to now, no effective vaccine has been available due to a limited cross protection of vaccinal strains on field strains and a high genetic diversity of Ehrlichia ruminantium within geographical locations. To address this issue, we inferred the genetic diversity and population structure of 194 E. ruminantium isolates circulating worldwide using Multilocus Sequence Typing based on lipA, lipB, secY, sodB , and sucA genes . Phylogenetic trees and networks were generated using BEAST and SplitsTree, respectively, and recombination between the different genetic groups was tested using the PHI test for recombination. Our study reveals the repeated occurrence of recombination between E. ruminantium strains, suggesting that it may occur frequently in the genome and has likely played an important role in the maintenance of genetic diversity and the evolution of E. ruminantium . Despite the unclear phylogeny and phylogeography, E. ruminantium isolates are clustered into two main groups: Group 1 (West Africa) and a Group 2 (worldwide) which is represented by West, East, and Southern Africa, Indian Ocean, and Caribbean strains. Some sequence types are common between West Africa and Caribbean and between Southern Africa and Indian Ocean strains. These common sequence types highlight two main introduction events due to the movement of cattle: from West Africa to Caribbean and from Southern Africa to the Indian Ocean islands. Due to the long branch lengths between Group 1 and Group 2, and the propensity for recombination between these groups, it seems that the West African clusters of Subgroup 2 arrived there more recently than the original divergence of the two groups, possibly with the original waves of domesticated ruminants that spread across the African continent several thousand years ago.

  3. Morpho morphometrics: Shared ancestry and selection drive the evolution of wing size and shape in Morpho butterflies.

    Science.gov (United States)

    Chazot, Nicolas; Panara, Stephen; Zilbermann, Nicolas; Blandin, Patrick; Le Poul, Yann; Cornette, Raphaël; Elias, Marianne; Debat, Vincent

    2016-01-01

    Butterfly wings harbor highly diverse phenotypes and are involved in many functions. Wing size and shape result from interactions between adaptive processes, phylogenetic history, and developmental constraints, which are complex to disentangle. Here, we focus on the genus Morpho (Nymphalidae: Satyrinae, 30 species), which presents a high diversity of sizes, shapes, and color patterns. First, we generate a comprehensive molecular phylogeny of these 30 species. Next, using 911 collection specimens, we quantify the variation of wing size and shape across species, to assess the importance of shared ancestry, microhabitat use, and sexual selection in the evolution of the wings. While accounting for phylogenetic and allometric effects, we detect a significant difference in wing shape but not size among microhabitats. Fore and hindwings covary at the individual and species levels, and the covariation differs among microhabitats. However, the microhabitat structure in covariation disappears when phylogenetic relationships are taken into account. Our results demonstrate that microhabitat has driven wing shape evolution, although it has not strongly affected forewing and hindwing integration. We also found that sexual dimorphism of forewing shape and color pattern are coupled, suggesting a common selective force. © 2015 The Author(s). Evolution © 2015 The Society for the Study of Evolution.

  4. Cell–cell signaling drives the evolution of complex traits: introduction—lung evo-devo

    Science.gov (United States)

    Torday, John S.; Rehan, V. K.

    2009-01-01

    Physiology integrates biology with the environment through cell–cell interactions at multiple levels. The evolution of the respiratory system has been “deconvoluted” (Torday and Rehan in Am J Respir Cell Mol Biol 31:8–12, 2004) through Gene Regulatory Networks (GRNs) applied to cell–cell communication for all aspects of lung biology development, homeostasis, regeneration, and aging. Using this approach, we have predicted the phenotypic consequences of failed signaling for lung development, homeostasis, and regeneration based on evolutionary principles. This cell–cell communication model predicts other aspects of vertebrate physiology as adaptational responses. For example, the oxygen-induced differentiation of alveolar myocytes into alveolar adipocytes was critical for the evolution of the lung in land dwelling animals adapting to fluctuating Phanarezoic oxygen levels over the past 500 million years. Adipocytes prevent lung injury due to oxygen radicals and facilitate the rise of endothermy. In addition, they produce the class I cytokine leptin, which augments pulmonary surfactant activity and alveolar surface area, increasing selection pressure for both respiratory oxygenation and metabolic demand initially constrained by high-systemic vascular pressure, but subsequently compensated by the evolution of the adrenomedullary beta-adrenergic receptor mechanism. Conserted positive selection for the lung and adrenals created further selection pressure for the heart, which becomes progressively more complex phylogenetically in tandem with the lung. Developmentally, increasing heart complexity and size impinges precociously on the gut mesoderm to induce the liver. That evolutionary-developmental interaction is significant because the liver provides regulated sources of glucose and glycogen to the evolving physiologic system, which is necessary for the evolution of the neocortex. Evolution of neocortical control furthers integration of physiologic systems. Such

  5. Selective forces and mutational biases drive stop codon usage in the human genome: a comparison with sense codon usage.

    Science.gov (United States)

    Trotta, Edoardo

    2016-05-17

    The three stop codons UAA, UAG, and UGA signal the termination of mRNA translation. As a result of a mechanism that is not adequately understood, they are normally used with unequal frequencies. In this work, we showed that selective forces and mutational biases drive stop codon usage in the human genome. We found that, in respect to sense codons, stop codon usage was affected by stronger selective forces but was less influenced by neutral mutational biases. UGA is the most frequent termination codon in human genome. However, UAA was the preferred stop codon in genes with high breadth of expression, high level of expression, AT-rich coding sequences, housekeeping functions, and in gene ontology categories with the largest deviation from expected stop codon usage. Selective forces associated with the breadth and the level of expression favoured AT-rich sequences in the mRNA region including the stop site and its proximal 3'-UTR, but acted with scarce effects on sense codons, generating two regions, upstream and downstream of the stop codon, with strongly different base composition. By favouring low levels of GC-content, selection promoted labile local secondary structures at the stop site and its proximal 3'-UTR. The compositional and structural context favoured by selection was surprisingly emphasized in the class of ribosomal proteins and was consistent with sequence elements that increase the efficiency of translational termination. Stop codons were also heterogeneously distributed among chromosomes by a mechanism that was strongly correlated with the GC-content of coding sequences. In human genome, the nucleotide composition and the thermodynamic stability of stop codon site and its proximal 3'-UTR are correlated with the GC-content of coding sequences and with the breadth and the level of gene expression. In highly expressed genes stop codon usage is compositionally and structurally consistent with highly efficient translation termination signals.

  6. Coevolution with bacteria drives the evolution of aerobic fermentation in Lachancea kluyveri.

    Directory of Open Access Journals (Sweden)

    Nerve Zhou

    Full Text Available The Crabtree positive yeasts, such as Saccharomyces cerevisiae, prefer fermentation to respiration, even under fully aerobic conditions. The selective pressures that drove the evolution of this trait remain controversial because of the low ATP yield of fermentation compared to respiration. Here we propagate experimental populations of the weak-Crabtree yeast Lachancea kluyveri, in competitive co-culture with bacteria. We find that L. kluyveri adapts by producing quantities of ethanol lethal to bacteria and evolves several of the defining characteristics of Crabtree positive yeasts. We use precise quantitative analysis to show that the rate advantage of fermentation over aerobic respiration is insufficient to provide an overall growth advantage. Thus, the rapid consumption of glucose and the utilization of ethanol are essential for the success of the aerobic fermentation strategy. These results corroborate that selection derived from competition with bacteria could have provided the impetus for the evolution of the Crabtree positive trait.

  7. Neofunctionalization of Duplicated P450 Genes Drives the Evolution of Insecticide Resistance in the Brown Planthopper.

    Science.gov (United States)

    Zimmer, Christoph T; Garrood, William T; Singh, Kumar Saurabh; Randall, Emma; Lueke, Bettina; Gutbrod, Oliver; Matthiesen, Svend; Kohler, Maxie; Nauen, Ralf; Davies, T G Emyr; Bass, Chris

    2018-01-22

    Gene duplication is a major source of genetic variation that has been shown to underpin the evolution of a wide range of adaptive traits [1, 2]. For example, duplication or amplification of genes encoding detoxification enzymes has been shown to play an important role in the evolution of insecticide resistance [3-5]. In this context, gene duplication performs an adaptive function as a result of its effects on gene dosage and not as a source of functional novelty [3, 6-8]. Here, we show that duplication and neofunctionalization of a cytochrome P450, CYP6ER1, led to the evolution of insecticide resistance in the brown planthopper. Considerable genetic variation was observed in the coding sequence of CYP6ER1 in populations of brown planthopper collected from across Asia, but just two sequence variants are highly overexpressed in resistant strains and metabolize imidacloprid. Both variants are characterized by profound amino-acid alterations in substrate recognition sites, and the introduction of these mutations into a susceptible P450 sequence is sufficient to confer resistance. CYP6ER1 is duplicated in resistant strains with individuals carrying paralogs with and without the gain-of-function mutations. Despite numerical parity in the genome, the susceptible and mutant copies exhibit marked asymmetry in their expression with the resistant paralogs overexpressed. In the primary resistance-conferring CYP6ER1 variant, this results from an extended region of novel sequence upstream of the gene that provides enhanced expression. Our findings illustrate the versatility of gene duplication in providing opportunities for functional and regulatory innovation during the evolution of an adaptive trait. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  8. Study on Law of Groundwater Evolution under Natural and Artificial Forcing with Case study of Haihe River Basin

    Science.gov (United States)

    You, Jinjun; Gan, Hong; Wang, Lin; Bi, Xue; Du, Sisi

    2010-05-01

    The evolution of groundwater is one of the key problems of water cycle study. It is a result of joint effect of natural condition and human activities, but until now the driving forces of groundwater system evolution were not fully understood due to the complexity of groundwater system structures and the uncertainty of affecting factors. Geology, precipitation and human activity are the main factors affecting the groundwater system evolution and interact each other, but the influence of such three factors on groundwater system are not clarified clearly on a macroscopic scale. The precipitation changes the volume of water recharge and the groundwater pumping effect the discharge of groundwater. Another important factor influencing balance of groundwater storage is the underlaying that affects the renewablility of groundwater. The underlaying is decided mainly by geological attributes but also influenced by human activited. The macroscopic environment of groundwater evolves under the natural and anthropic factors. This paper study the general law of groundwater evolution among the factors based on the case study in Haihe River Basin, a typical area with dramatic groundwater change under natural precipitation attenuation and gradually increase of water suuply. Haihe River Basin is located in north-China, covers an area of 320,041 km2 with over 40% plain areas. The plain area of Haihe Basin is densely populated with many large and medium-sized cities, including metropolis of Beijing and Tianjin, and concentrated irrigated areas, playing important roles in China's economy and food production. It is the unique basin where groundwater occupies majority of total water supply in China. Long-term groundwater over-exploitation causes a series of ecological and environmental problems that threats the sustainable development. In this paper, the historical process of groundwater balance in Haihe Basin is divided into three phases by decrease of rainfall and increase of water

  9. Supply Chain Management as a Driving Force for Generating Competitive Advantage for Dairy Companies

    Directory of Open Access Journals (Sweden)

    Irina Olegovna Poleshkina

    2016-11-01

    Full Text Available The study aims to uncover the reserves to generate competitive advantages for the participants of the market of perishables in the case of the dairy sector due to the formation of effective supply chains, as this category of goods is the most demanding in terms of periods and conditions of transportation and terms of preservation. The research technique is based on the concepts of value chains and supply chain management. In order to optimize the distribution of functions between the participants of the dairy chain a process-based approach has been applied. The research has revealed the main reasons for high aggregate costs and the places of their formation at each stage of the dairy supply chain. The article proposes the mechanisms to address three main problems arising from the process of building relations between the participants of the dairy supply chain in Russia. These problems are associated with a disproportionate margin distribution between the participants of the chain, with non-compliance of the quality of raw milk with the requirements for the production of specific types of dairy products, and with distrust of the supply chain participants, which increases transaction costs and forces to create reserve supplies which reduce the competitiveness of the whole dairy supply chain in general. In order to improve the competitiveness of all participants in the dairy chain, the article presents several mechanisms for solving these problems. The first is margin distribution based on the costs incurred by each participant of the dairy chain. The second is the use of a mathematical model to determine the assortment of goods of a dairy enterprise on the basis of the incoming volume and quality of raw milk according to the seasonal factor and the demand for dairy products. The third is the feasibility of refusal from the formation of reserve supplies by all participants of the dairy chain, which will not only minimize aggregate costs, but also

  10. High temperature reactor: Driving force to convert CO2 to fuel - HTR2008-58132

    International Nuclear Information System (INIS)

    McCormick, J. L.

    2008-01-01

    The rapidly increasing cost of petroleum products and uncertainty of long-term supply have prompted the U.S. military to aggressively pursue production of alternative fuels (synfuels) such as coal-to-liquids (CTL). U.S. Air Force is particularly active in this effort while the entire military is involved in simultaneously developing fuel specifications for alternative fuels that enable a single fuel for the entire battle space; all ground vehicles, aircraft and fuel cells. By limiting its focus on coal, tar sands and oil shale resources, the military risks violating federal law which requires the use of synfuels that have life cycle greenhouse gas emissions less than or equal to emissions from conventional petroleum fuels. A climate-friendly option would use a high temperature nuclear reactor to split water. The hydrogen (H 2 ) would be used in the reverse water gas shift (RWGS) to react with carbon dioxide (CO 2 ) to produce carbon monoxide (CO) and water. The oxygen (O 2 ) would be fed into a supercritical (SC) coal furnace. The flue gas CO 2 emissions would be stripped of impurities before reacting with H 2 in a RWGS process. Resultant carbon monoxide (CO) is fed, with additional H2, (extra H 2 needed to adjust the stoichiometry: 2 moles H 2 to one mole CO) into a conventional Fischer-Tropsch synthesis (FTS) to produce a heavy wax which is cracked and isomerized and refined to Jet Propulsion 8 (JP-8) and Jet Propulsion 5 (JP-5) fuels. The entire process offers valuable carbon-offsets and multiple products that contribute to lower syn-fuel costs and to comply with the federal limitation imposed on syn-fuel purchases. While the entire process is not commercially available, component parts are being researched; their physical and chemical properties understood and some are state-of-the-art technologies. An international consortium should complete physical, chemical and economic flow sheets to determine the feasibility of this concept that, if pursued, has broad

  11. The deprivation syndrome is the driving force of phylogeny, ontogeny and oncogeny.

    Science.gov (United States)

    Heininger, K

    2001-01-01

    Energy is the motor of life. Energy ensures the organism's survival and competitive advantage for reproductive success. For almost 3 billion years, unicellular organisms were the only life form on earth. Competition for limited energy resources and raw materials exerted an incessant selective pressure on organisms. In the adverse environment and due to their 'feast and famine' life style, hardiness to a variety of stressors, particularly to nutrient deprivation, was the selection principle. Both resistance and mutagenic adaptation to stressors were established as survival strategies by means of context-specific processes creating stability or variability of DNA sequence. The conservation of transduction pathways and functional homology of effector molecules clearly bear witness that the principles of life established during prokaryotic and eukaryotic unicellular evolution, although later diversified, have been unshakably cast to persist during metazoan phylogenesis. A wealth of evidence suggests that unicellular organisms evolved the phenomena of differentiation and apoptosis, sexual reproduction, and even aging, as responses to environmental challenges. These evolutionary accomplishments were elaborated from the dichotomous resistance/mutagenesis response and sophisticated the capacity of cells to tune their genetic information to changing environmental conditions. Notably, the social deprivation responses, differentiation and apoptosis, evolved as intercellularly coordinated events: a multitude of differentiation processes were elaborated from sporulation, the prototypic stress resistance response, while apoptosis, contrary to current concepts, is no altruistic cell suicide but was programmed as a mutagenic survival response; this response, however, is socially thwarted leading into mutagenic error catastrophe. In the hybrid differentiation-apoptosis process, cytocide and cannibalism of apoptotic cells thus serve the purpose of fueling the survival of the selfish

  12. Evolution of phase structure and giant strain at low driving fields in Bi-based lead-free incipient piezoelectrics

    International Nuclear Information System (INIS)

    Maqbool, Adnan; Hussain, Ali; Malik, Rizwan Ahmed; Rahman, Jamil Ur; Zaman, Arif; Song, Tae Kwon; Kim, Won-Jeong; Kim, Myong-Ho

    2015-01-01

    Graphical abstract: - Highlights: • Nb-doped BNBT–SZ ceramics were prepared by conventional solid state method. • A giant normalized strain of 825 pm/V at 4 kV/mm was achieved. • A large strain of 0.20% triggered at a relatively low field of 3 kV/mm. • Highest strain obtained in BNT-based ceramics at such a low driving field. • Ferroelectric to ergodic-relaxor phase transition occurred with Nb-doping. - Abstract: Lead-free 0.99[(Bi 0.5 Na 0.5 ) 0.935 Ba 0.065 Ti (1–x) Nb x O 3 ]–0.01SrZrO 3 (BNBTNb100x–SZ, with Nb100x = 0–1) ceramics were prepared by the conventional mixed oxide route. X-ray diffraction and Raman scattering was utilized for the structural evolution of Nb-modified BNBT–SZ ceramics at average and short-scale localized structure. Temperature dependent dielectric properties showed ferroelectric–ergodic relaxor (FE–ER) transition in Nb-modified BNBT–SZ ceramics by producing a significant disruption of the long-range FE order. A giant normalized strain of 825 pm/V at 4 kV/mm was achieved at Nb1.0. Interestingly, at a relatively low applied field of 3 kV/mm, the Nb0.75 sample displayed a large electric field-induced strain (EFIS) response of 0.20%, which is highest value obtained in non-textured lead-free BNT-based ceramics at such low driving field. The structural distortion induced by doping and electric poling is correlated with the dielectric, ferroelectric and EFIS response, and the evolution of giant strain was ascribed to reversible field induced phase transition from ER–FE phase

  13. Evolutionary mechanisms driving the evolution of a large polydnavirus gene family coding for protein tyrosine phosphatases

    Directory of Open Access Journals (Sweden)

    Serbielle Céline

    2012-12-01

    Full Text Available Abstract Background Gene duplications have been proposed to be the main mechanism involved in genome evolution and in acquisition of new functions. Polydnaviruses (PDVs, symbiotic viruses associated with parasitoid wasps, are ideal model systems to study mechanisms of gene duplications given that PDV genomes consist of virulence genes organized into multigene families. In these systems the viral genome is integrated in a wasp chromosome as a provirus and virus particles containing circular double-stranded DNA are injected into the parasitoids’ hosts and are essential for parasitism success. The viral virulence factors, organized in gene families, are required collectively to induce host immune suppression and developmental arrest. The gene family which encodes protein tyrosine phosphatases (PTPs has undergone spectacular expansion in several PDV genomes with up to 42 genes. Results Here, we present strong indications that PTP gene family expansion occurred via classical mechanisms: by duplication of large segments of the chromosomally integrated form of the virus sequences (segmental duplication, by tandem duplications within this form and by dispersed duplications. We also propose a novel duplication mechanism specific to PDVs that involves viral circle reintegration into the wasp genome. The PTP copies produced were shown to undergo conservative evolution along with episodes of adaptive evolution. In particular recently produced copies have undergone positive selection in sites most likely involved in defining substrate selectivity. Conclusion The results provide evidence about the dynamic nature of polydnavirus proviral genomes. Classical and PDV-specific duplication mechanisms have been involved in the production of new gene copies. Selection pressures associated with antagonistic interactions with parasitized hosts have shaped these genes used to manipulate lepidopteran physiology with evidence for positive selection involved in

  14. Life on the rocks: habitat use drives morphological and performance evolution in lizards.

    Science.gov (United States)

    Goodman, Brett A; Miles, Donald B; Schwarzkopf, Lin

    2008-12-01

    As a group, lizards occupy a vast array of habitats worldwide, yet there remain relatively few cases where habitat use (ecology), morphology, and thus, performance, are clearly related. The best known examples include: increased limb length in response to increased arboreal perch diameter in anoles and increased limb length in response to increased habitat openness for some skinks. Rocky habitats impose strong natural selection on specific morphological characteristics, which differs from that imposed on terrestrial species, because moving about on inclined substrates of irregular sizes and shapes constrains locomotor performance in predictable ways. We quantified habitat use, morphology, and performance of 19 species of lizards (family Scincidae, subfamily Lygosominae) from 23 populations in tropical Australia. These species use habitats with considerable variation in rock availability. Comparative phylogenetic analyses revealed that occupation of rock-dominated habitats correlated with the evolution of increased limb length, compared to species from forest habitats that predominantly occupied leaf litter. Moreover, increased limb length directly affected performance, with species from rocky habitats having greater sprinting, climbing, and clinging ability than their relatives from less rocky habitats. Thus, we found that the degree of rock use is correlated with both morphological and performance evolution in this group of tropical lizards.

  15. Driving forces behind the increasing cardiovascular treatment intensity.A dynamic epidemiologic model of trends in Danish cardiovascular drug utilization.

    DEFF Research Database (Denmark)

    Kildemoes, Helle Wallach; Andersen, Morten

    . Objectives: To investigate the driving forces behind the increasing treatment prevalence of cardiovascular drugs, in particular statins, by means of a dynamic epidemiologic drug utilization model. Methods: Material: All Danish residents older than 20 years by January 1, 1996 (4.0 million inhabitants), were...

  16. Driving forces behind the increasing cardiovascular treatment intensity.A dynamic epidemiologic model of trends in Danish cardiovascular drug utilization.

    DEFF Research Database (Denmark)

    Kildemoes, Helle Wallach; Andersen, Morten

    . Objectives: To investigate the driving forces behind the increasing treatment prevalence of cardiovascular drugs, in particular statins, by means of a dynamic epidemiologic drug utilization model. Methods: Material: All Danish residents older than 20 years by January 1, 1996 (4.0 million inhabitants), were...

  17. From inflation to recent cosmic acceleration: the fermionic Elko field driving the evolution of the universe

    Energy Technology Data Exchange (ETDEWEB)

    Pereira, S.H.; Guimarães, T.M., E-mail: shpereira@feg.unesp.br, E-mail: thiago.mogui@gmail.com [Universidade Estadual Paulista (Unesp), Faculdade de Engenharia, Guaratinguetá, Departamento de Física e Química, Av. Dr. Ariberto Pereira da Cunha 333, 12516-410, Guaratinguetá, SP (Brazil)

    2017-09-01

    In this paper we construct the complete evolution of the universe driven by the mass dimension one dark spinor called Elko, starting with inflation, passing by the matter dominated era and finishing with the recent accelerated expansion. The dynamic of the fermionic Elko field with a symmetry breaking type potential can reproduce all phases of the universe in a natural and elegant way. The dynamical equations in general case and slow roll conditions in the limit H || m {sub pl} are also presented for the Elko system. Numerical analysis for the number of e-foldings during inflation, energy density after inflation and for present time and also the actual size of the universe are in good agreement with the standard model of cosmology. An interpretation of the inflationary phase as a result of Pauli exclusion principle is also possible if the Elko field is treated as an average value of its quantum analogue.

  18. Is personality a driving force for socioeconomic differences in young adults' health care use? A prospective cohort study.

    Science.gov (United States)

    Kraft, Maren; Arts, Koos; Traag, Tanja; Otten, Ferdy; Bosma, Hans

    2017-09-01

    To relate personality characteristics at the age of 12 to socioeconomic differences in health care use in young adulthood. And thereby examining the extent to which socioeconomic differences in the use of health care in young adulthood are based on differences in personality characteristics, independent of the (parental) socioeconomic background. Personality of more than 13,000 Dutch 12-year old participants was related to their health and socioeconomic position after a follow-up of 13 years (when the participants had become young adults). In young adulthood, low socioeconomic status was related to high health care use (e.g. low education -hospital admission: OR = 2.21; low income -GP costs: OR = 1.25). Odds ratios (for the socioeconomic health differences) did not decrease when controlled for personality. In this Dutch sample of younger people, personality appeared not to be a driving force for socioeconomic differences in health care use. Findings thus do not support the personality-related, indirect selection perspective on the explanation of socioeconomic differences in health.

  19. Driving forces in energy-related CO2 emissions in south and east coastal China: commonality and variations

    Science.gov (United States)

    Gao, C.; Liu, Y.; Jin, J.; Wei, T.

    2015-12-01

    East and south coastal China contributes to respectively about 30% and 8% of CO2 emissions in China and the world, and therefore play a critical role in achieving the national goal of emission reduction to mitigate the global warming. It also serves as a benchmark for the less developed regions of China, in terms of achieving the developed world's human development standard under lower per capita emissions. We analyze the driving forces of emissions in this region and their provincial characteristics by applying the Logarithmic Mean Divisia Index method. Our findings show that emissions have been doubled during the period from 2000 to 2012, along with three and two folds increase in economy and energy consumption, respectively. This suggests a persistent lock between economic growth and emissions, even in this socioeconomically advanced region in China. Provincial difference in annual emission growth reveals three distinguished low-carbon developmental stages, owning mainly to the effectiveness of energy efficiency in reducing emission growth. This may explain why previous climate policies have aimed to reduce carbon intensity. These results indicate that targeted measures on enhancing energy efficiency in the short term and de-carbonization of both the economic and energy structure in the long term can lower the emission growth more effectively and efficiently. They also suggest that factor-driven emission reduction strategies and policies are needed in the geographically and socioeconomically similar regions.

  20. Spatiotemporal Pattern and Driving Forces of Arable Land-Use Intensity in China: Toward Sustainable Land Management Using Emergy Analysis

    Directory of Open Access Journals (Sweden)

    Hualin Xie

    2014-05-01

    Full Text Available The level of arable land-use intensity has important impacts on food security and rural sustainable development. Using the emergy method, we investigate the spatial disparities and driving forces of arable land-use intensity in China from 1999 to 2008 at the national, regional and provincial levels. The empirical results show that chemical fertilizer was the largest component of agricultural inputs and that agricultural diesel oil recorded the highest growth rate. The degree of heterogeneities in arable land-use intensity in China showed a decreasing trend, which resulted mainly from the differences among the eastern, northeastern, central and western regions. The regional disparities in labor, pesticides and plastic sheeting decreased from 1999 to 2008. The per capita annual net incomes of household operations and the agricultural policies had a significant positive correlation with total inputs, fertilizer inputs, pesticide inputs and agricultural plastic sheeting. In addition, the nonagricultural population had a greater impact on agricultural plastic sheeting. Finally, we suggest that there is an urgent need to focus on the effects of chemical fertilizer and pesticide inputs on the ecological environment. Agricultural support policies should be introduced for the poor agricultural production provinces.

  1. Application of driving force- Pressure- State- Impact- Response (DPSIR Framework for Analyzing the Human habitat in City of Tehran

    Directory of Open Access Journals (Sweden)

    Esmail Salehi

    2015-09-01

    Full Text Available Human habitat change is a complicated issue that many factors play different roles in its formation and distribution. Considering this complication, a more comprehensive and holistic approach is needed for a better understanding and management of those factors. The causal frameworks are among systemic and integrated methods for addressing the causes of environmental problems and the relationships that exist between the environmental systems for proposing proper solutions. The DPSIR model is a functional analysis framework to depict the cause-effect relationships that exist in creating environmental problems. Tehran is one of the major megacities in the Middle East that faces environmental consequences of over population and unplanned urban sprawl, and because of its location in arid region, its vulnerable to rise of environmental problem. In this research, by using the DPSIR framework, different aspects of habitat condition of Tehran are analyzed and later with the help of this conceptual framework, strategies for controlling urban environment. The results show that urbanization is the major driving force that is induced by overpopulation and the need for further urban sprawl, which cause pressure on natural resources. The state of housing and rapid land use changes have brought about unfavorable living conditions that result in unfavorable impacts on public health and safety, which are the results of ineffective policies and solutions.

  2. The Driving Forces for the Practice of Strategic Planning in SMEs: Evidence from Harare Metropolitan Province, Zimbabwe

    Directory of Open Access Journals (Sweden)

    Maxwell Sandada

    2016-08-01

    Full Text Available Despite Zimbabwe sharing with the rest of the world, the notion that SMEs are the impeccable engines to economic revival, growth and development, many of the nation`s SMEs are plagued with high failure rates. Previous studies carried out in most foreign countries suggested that the high failure rate of SMEs was attributable to lack of strategic planning among a host of other factors. Against this backdrop, the purpose of this study was to examine the driving forces for the practice of strategic planning in SMEs. A quantitative cross sectional study was conducted among active SMEs who are registered with the Ministry of Small and Medium Enterprises and Cooperative Development in Zimbabwe. The study revealed that globalisation, business ownership motivations, environmental dynamism and innovation & technological advancement have a positive and statistically significant influence on the adoption or practice of strategic planning among SMEs. The study has important implications for the practice and implementation of strategic planning among SMEs especially in the context of a developing country such as Zimbabwe.

  3. Evolution of etched nuclear track profiles of alpha particles in CR-39 by atomic force microscopy

    International Nuclear Information System (INIS)

    Félix-Bautista, R.; Hernández-Hernández, C.; Zendejas-Leal, B.E.; Fragoso, R.; Golzarri, J.I.; Vázquez-López, C.; Espinosa, G.

    2013-01-01

    A series of atomic force microscopy (AFM) images of etched nuclear tracks has been obtained and used to calculate the nuclear track registration sensitivity parameter V(x) = Vt(x)/Vb. Due to the AFM limitations the samples were irradiated normally to the surface, and with energies attenuated in order to include the Bragg peak region in the AFM piezo-scanner z movement range. The simulation of the track profile evolution was then obtained. The different stages of etched nuclear track profiles were rendered. - Highlights: ► Using AFM we reach that Bragg peak region of etched tracks in CR-39. ► The etched track sensitivity V was calculated by data obtained by AFM. ► The evolucion of etched nuclear tracks was simulated by data achieved by AFM

  4. What drives the evolution of Luminous Compact Blue Galaxies in Clusters vs. the Field?

    Science.gov (United States)

    Wirth, Gregory D.; Bershady, Matthew A.; Crawford, Steven M.; Hunt, Lucas; Pisano, Daniel J.; Randriamampandry, Solohery M.

    2018-06-01

    Low-mass dwarf ellipticals are the most numerous members of present-day galaxy clusters, but the progenitors of this dominant population remain unclear. A prime candidate is the class of objects known as Luminous Compact Blue Galaxies (LCBGs), common in intermediate-redshift clusters but virtually extinct today. Recent cosmological simulations suggest that present-day dwarf galaxies begin as irregular field galaxies, undergo an environmentally-driven starburst phase as they enter the cluster, and stop forming stars earlier than their counterparts in the field. This model predicts that cluster dwarfs should have lower stellar mass per unit dynamical mass than their counterparts in the field. We are undertaking a two-pronged archival research program to test this key prediction using the combination of precision photometry from space and high-quality spectroscopy. First, we are combining optical HST/ACS imaging of five z=0.55 clusters (including two HST Frontier Fields) with Spitzer IR imaging and publicly-released Keck/DEIMOS spectroscopy to measure stellar-to-dynamical-mass ratios for a large sample of cluster LCBGs. Second, we are exploiting a new catalog of LCBGs in the COSMOS field to gather corresponding data for a significant sample of field LCBGs. By comparing mass ratios from these datasets, we aim to test theoretical predictions and determine the primary physical driver of cluster dwarf-galaxy evolution.

  5. Positive selection rather than relaxation of functional constraint drives the evolution of vision during chicken domestication.

    Science.gov (United States)

    Wang, Ming-Shan; Zhang, Rong-Wei; Su, Ling-Yan; Li, Yan; Peng, Min-Sheng; Liu, He-Qun; Zeng, Lin; Irwin, David M; Du, Jiu-Lin; Yao, Yong-Gang; Wu, Dong-Dong; Zhang, Ya-Ping

    2016-05-01

    As noted by Darwin, chickens have the greatest phenotypic diversity of all birds, but an interesting evolutionary difference between domestic chickens and their wild ancestor, the Red Junglefowl, is their comparatively weaker vision. Existing theories suggest that diminished visual prowess among domestic chickens reflect changes driven by the relaxation of functional constraints on vision, but the evidence identifying the underlying genetic mechanisms responsible for this change has not been definitively characterized. Here, a genome-wide analysis of the domestic chicken and Red Junglefowl genomes showed significant enrichment for positively selected genes involved in the development of vision. There were significant differences between domestic chickens and their wild ancestors regarding the level of mRNA expression for these genes in the retina. Numerous additional genes involved in the development of vision also showed significant differences in mRNA expression between domestic chickens and their wild ancestors, particularly for genes associated with phototransduction and photoreceptor development, such as RHO (rhodopsin), GUCA1A, PDE6B and NR2E3. Finally, we characterized the potential role of the VIT gene in vision, which experienced positive selection and downregulated expression in the retina of the village chicken. Overall, our results suggest that positive selection, rather than relaxation of purifying selection, contributed to the evolution of vision in domestic chickens. The progenitors of domestic chickens harboring weaker vision may have showed a reduced fear response and vigilance, making them easier to be unconsciously selected and/or domesticated.

  6. Both selective and neutral processes drive GC content evolution in the human genome

    Directory of Open Access Journals (Sweden)

    Cagliani Rachele

    2008-03-01

    Full Text Available Abstract Background Mammalian genomes consist of regions differing in GC content, referred to as isochores or GC-content domains. The scientific debate is still open as to whether such compositional heterogeneity is a selected or neutral trait. Results Here we analyze SNP allele frequencies, retrotransposon insertion polymorphisms (RIPs, as well as fixed substitutions accumulated in the human lineage since its divergence from chimpanzee to indicate that biased gene conversion (BGC has been playing a role in within-genome GC content variation. Yet, a distinct contribution to GC content evolution is accounted for by a selective process. Accordingly, we searched for independent evidences that GC content distribution does not conform to neutral expectations. Indeed, after correcting for possible biases, we show that intron GC content and size display isochore-specific correlations. Conclusion We consider that the more parsimonious explanation for our results is that GC content is subjected to the action of both weak selection and BGC in the human genome with features such as nucleosome positioning or chromatin conformation possibly representing the final target of selective processes. This view might reconcile previous contrasting findings and add some theoretical background to recent evidences suggesting that GC content domains display different behaviors with respect to highly regulated biological processes such as developmentally-stage related gene expression and programmed replication timing during neural stem cell differentiation.

  7. Evolution of Muscle Activity Patterns Driving Motions of the Jaw and Hyoid during Chewing in Gnathostomes

    Science.gov (United States)

    Konow, Nicolai; Herrel, Anthony; Ross, Callum F.; Williams, Susan H.; German, Rebecca Z.; Sanford, Christopher P. J.; Gintof, Chris

    2011-01-01

    Although chewing has been suggested to be a basal gnathostome trait retained in most major vertebrate lineages, it has not been studied broadly and comparatively across vertebrates. To redress this imbalance, we recorded EMG from muscles powering anteroposterior movement of the hyoid, and dorsoventral movement of the mandibular jaw during chewing. We compared muscle activity patterns (MAP) during chewing in jawed vertebrate taxa belonging to unrelated groups of basal bony fishes and artiodactyl mammals. Our aim was to outline the evolution of coordination in MAP. Comparisons of activity in muscles of the jaw and hyoid that power chewing in closely related artiodactyls using cross-correlation analyses identified reorganizations of jaw and hyoid MAP between herbivores and omnivores. EMG data from basal bony fishes revealed a tighter coordination of jaw and hyoid MAP during chewing than seen in artiodactyls. Across this broad phylogenetic range, there have been major structural reorganizations, including a reduction of the bony hyoid suspension, which is robust in fishes, to the acquisition in a mammalian ancestor of a muscle sling suspending the hyoid. These changes appear to be reflected in a shift in chewing MAP that occurred in an unidentified anamniote stem-lineage. This shift matches observations that, when compared with fishes, the pattern of hyoid motion in tetrapods is reversed and also time-shifted relative to the pattern of jaw movement. PMID:21705368

  8. Directional selection can drive the evolution of modularity in complex traits.

    Science.gov (United States)

    Melo, Diogo; Marroig, Gabriel

    2015-01-13

    Modularity is a central concept in modern biology, providing a powerful framework for the study of living organisms on many organizational levels. Two central and related questions can be posed in regard to modularity: How does modularity appear in the first place, and what forces are responsible for keeping and/or changing modular patterns? We approached these questions using a quantitative genetics simulation framework, building on previous results obtained with bivariate systems and extending them to multivariate systems. We developed an individual-based model capable of simulating many traits controlled by many loci with variable pleiotropic relations between them, expressed in populations subject to mutation, recombination, drift, and selection. We used this model to study the problem of the emergence of modularity, and hereby show that drift and stabilizing selection are inefficient at creating modular variational structures. We also demonstrate that directional selection can have marked effects on the modular structure between traits, actively promoting a restructuring of genetic variation in the selected population and potentially facilitating the response to selection. Furthermore, we give examples of complex covariation created by simple regimes of combined directional and stabilizing selection and show that stabilizing selection is important in the maintenance of established covariation patterns. Our results are in full agreement with previous results for two-trait systems and further extend them to include scenarios of greater complexity. Finally, we discuss the evolutionary consequences of modular patterns being molded by directional selection.

  9. Land use change and its driving forces toward mutual conversion in Zhangjiakou City, a farming-pastoral ecotone in Northern China.

    Science.gov (United States)

    Liu, Chao; Xu, Yueqing; Sun, Piling; Huang, An; Zheng, Weiran

    2017-09-14

    Land use/cover change (LUCC), a local environmental issue of global importance, and its driving forces have been crucial issues in geography and environmental research. Previous studies primarily focused on major driving factors in various land use types, with few explorations of differences between driving forces of mutual land use type conversions, especially in fragile eco-environments. In this study, Zhangjiakou City, in a farming-pastoral ecotone in Northern China, was taken as an example to analyze land use change between 1989 and 2015, and explore the driving forces of mutual land use type conversions using canonical correlation analysis. Satellite images and government statistics, including social-economic and natural data, were used as sources. Arable land, forestland, and grassland formed the main land use structure. From 1989 to 2015 forestland, orchard land, and construction land significantly increased, while arable land, grassland, unused land, and water areas decreased. Conversions from grassland to forestland; from arable land to orchard land, forestland and construction land; and from unused land to grassland and forestland were the primary land use changes. Among these, the conversion from grassland to forestland had the highest ranking. Average annual precipitation and per capita net income of rural residents positively affected the conversion of arable land to forestland and unused land to grassland. GDP, total population, and urbanization rate contributed most significantly to converting arable land to construction land; total retail sales of social consumer goods, average annual temperature, and GDP had important positive influences in converting arable land to orchard land.

  10. Estimation of Longitudinal Force and Sideslip Angle for Intelligent Four-Wheel Independent Drive Electric Vehicles by Observer Iteration and Information Fusion.

    Science.gov (United States)

    Chen, Te; Chen, Long; Xu, Xing; Cai, Yingfeng; Jiang, Haobin; Sun, Xiaoqiang

    2018-04-20

    Exact estimation of longitudinal force and sideslip angle is important for lateral stability and path-following control of four-wheel independent driven electric vehicle. This paper presents an effective method for longitudinal force and sideslip angle estimation by observer iteration and information fusion for four-wheel independent drive electric vehicles. The electric driving wheel model is introduced into the vehicle modeling process and used for longitudinal force estimation, the longitudinal force reconstruction equation is obtained via model decoupling, the a Luenberger observer and high-order sliding mode observer are united for longitudinal force observer design, and the Kalman filter is applied to restrain the influence of noise. Via the estimated longitudinal force, an estimation strategy is then proposed based on observer iteration and information fusion, in which the Luenberger observer is applied to achieve the transcendental estimation utilizing less sensor measurements, the extended Kalman filter is used for a posteriori estimation with higher accuracy, and a fuzzy weight controller is used to enhance the adaptive ability of observer system. Simulations and experiments are carried out, and the effectiveness of proposed estimation method is verified.

  11. Changes in quality management for light water reactor fuel manufacturing: A utility's view of driving forces and status

    International Nuclear Information System (INIS)

    Huettmann, A.; Skusa, J.; Ketteler, M.

    2000-01-01

    Quality management in LWR fuel manufacturing for the use in German reactors is based on international guidelines and national/local authority requirements defined in operational licenses. The quality management is twofold and comprises a quality assurance system and the check of manufacturing documents including witnessing of fabrication processes and inspections. Utility and authority appointed technical expert witness manufacturing and take part in inspections performed by the manufacturer where the scope is strictly defined and does not provide possibilities of flexible responses to manufacturing occurrences. For future developments in quality management HEW supports strengthening the ideas of quality planning. Analysis of all factors influencing fuel reliability shall be performed prior to manufacturing. This will increase the efforts in reviewing of drawings and specifications. Included here shall be a review of processes that will be used in manufacturing. The qualification and robustness of processes shall be demonstrated with special qualification programs and analysis of manufacturing statistics. Instead of product/project related inspections the use of all manufacturing data will provide a complete picture of the manufacturing quality. By applying statistical methods it will be possible to identify trends in manufacturing before deviations occur. So the basic driving force to implement statistical process control for the utilities is the wish to get comprehensive information of delivered quality, whereas for manufacturers it might be to increase production yields and thus to lower costs. The introduction and full use of statistical process control requires open information about manufacturing processes and inspection results by the manufacturers. This might include data judged to be economically sensitive. It also requires changes in attitude at the utilities and appointed experts. HEW has started to review and change internal guidelines to allow

  12. Driving forces and their contribution to the recent decrease in sediment flux to ocean of major rivers in China.

    Science.gov (United States)

    Li, Tong; Wang, Shuai; Liu, Yanxu; Fu, Bojie; Zhao, Wenwu

    2018-09-01

    Understanding the mechanisms behind land-ocean sediment transport processes is crucial, due to the resulting impacts on the sustainable management of water and soil resources. This study investigated temporal trends and historical phases of sediment flux delivered to the sea by nine major rivers in China, while also quantifying the contribution of key anthropogenic and natural driving forces. During the past six decades, sediment flux from these nine major rivers exhibited a statistically significant negative trend, decreasing from 1.92Gtyr -1 during 1954-1968 to 1.39Gtyr -1 , 0.861Gtyr -1 and 0.335Gtyr -1 during 1969-1985, 1986-1999 and 2000-2016, respectively. We used a recently developed Sediment Identity approach and found that the sharp decrease in sediment load observed across China was mainly (~95%) caused by a reduction in sediment concentration. Reservoir construction exerted the strongest influence on land-ocean sediment fluxes, while soil conservation measures represented a secondary driver. Before 1999, soil erosion was not controlled effectively in China and reservoirs, especially large ones, played a dominant role in reducing riverine sediments. After 1999, soil erosion has gradually been brought under control across China, so that conservation measures directly accounted for ~40% of the observed decrease in riverine sediments. With intensifying human activities, it is predicted that the total sediment flux delivered to the sea by the nine major rivers will continue to decrease in the coming decades, although at a slower rate, resulting in severe challenges for the sustainable management of drainage basins and river deltas. Copyright © 2018 Elsevier B.V. All rights reserved.

  13. Impeller radial force evolution in a large double-suction centrifugal pump during startup at the shut-off condition

    Energy Technology Data Exchange (ETDEWEB)

    Zou, Zhichao [College of Water Resources and Civil Engineering, China Agricultural University, Beijing 100083 (China); Wang, Fujun, E-mail: wangfj@cau.edu.cn [College of Water Resources and Civil Engineering, China Agricultural University, Beijing 100083 (China); Beijing Engineering Research Center of Safety and Energy Saving Technology for Water Supply Network System, China Agricultural University, Beijing 100083 (China); Yao, Zhifeng [College of Water Resources and Civil Engineering, China Agricultural University, Beijing 100083 (China); Beijing Engineering Research Center of Safety and Energy Saving Technology for Water Supply Network System, China Agricultural University, Beijing 100083 (China); Tao, Ran [College of Water Resources and Civil Engineering, China Agricultural University, Beijing 100083 (China); Xiao, Ruofu [College of Water Resources and Civil Engineering, China Agricultural University, Beijing 100083 (China); Beijing Engineering Research Center of Safety and Energy Saving Technology for Water Supply Network System, China Agricultural University, Beijing 100083 (China); Li, Huaicheng [Shanghai Liancheng (Group) Co., Ltd., Shanghai 201812 (China)

    2016-12-15

    Highlights: • Conclude the characteristics of transient radial force in the startup process for a large double-suction centrifugal pump. • The overall direction of the radial force during startup process is also confirmed. • A formula used to calculate the transient radial force during startup process is proposed. • A relationship between radial force variation and axial vortex development in blade channel during the startup process is established. The mechanism of the radial force evolution is revealed. - Abstract: Double-suction centrifugal pumps play an important role in the main feedwater systems of nuclear power plant. The impeller radial force in a centrifugal pump varies dramatically during startup at the shut-off condition. In this study, the startup process of a large double-suction centrifugal pump is investigated using CFD. During testing, the impeller speed is accelerated from zero to its rated speed in 1.0 s (marked as t{sub 0}) and is then maintained at the rated speed. The results show that the radial force increase lags behind the impeller speed increase. At 0–0.4t{sub 0}, the radial force is small (approaching zero). At 0.4–1.4t{sub 0}, the radial force increases rapidly. After 1.4t{sub 0}, the average radial force stabilizes and reaches its maximum value of 55,619 N. The observed maximum radial force value during startup is approximately nine times as high as the radial force under rated condition. During startup, the overall radial force direction is proximate to the radial line located 25° from the volute tongue along circumferential direction. A transient radial force formula is proposed to evaluate the changes in radial force during startup. The streamline distribution in impeller passages and the impeller outlet pressure profile varying over time are produced. The relationship between radial force evolution and the varying axial-to-spiral vortex structure is analyzed. The radial force change mechanism is revealed. This research

  14. Impeller radial force evolution in a large double-suction centrifugal pump during startup at the shut-off condition

    International Nuclear Information System (INIS)

    Zou, Zhichao; Wang, Fujun; Yao, Zhifeng; Tao, Ran; Xiao, Ruofu; Li, Huaicheng

    2016-01-01

    Highlights: • Conclude the characteristics of transient radial force in the startup process for a large double-suction centrifugal pump. • The overall direction of the radial force during startup process is also confirmed. • A formula used to calculate the transient radial force during startup process is proposed. • A relationship between radial force variation and axial vortex development in blade channel during the startup process is established. The mechanism of the radial force evolution is revealed. - Abstract: Double-suction centrifugal pumps play an important role in the main feedwater systems of nuclear power plant. The impeller radial force in a centrifugal pump varies dramatically during startup at the shut-off condition. In this study, the startup process of a large double-suction centrifugal pump is investigated using CFD. During testing, the impeller speed is accelerated from zero to its rated speed in 1.0 s (marked as t_0) and is then maintained at the rated speed. The results show that the radial force increase lags behind the impeller speed increase. At 0–0.4t_0, the radial force is small (approaching zero). At 0.4–1.4t_0, the radial force increases rapidly. After 1.4t_0, the average radial force stabilizes and reaches its maximum value of 55,619 N. The observed maximum radial force value during startup is approximately nine times as high as the radial force under rated condition. During startup, the overall radial force direction is proximate to the radial line located 25° from the volute tongue along circumferential direction. A transient radial force formula is proposed to evaluate the changes in radial force during startup. The streamline distribution in impeller passages and the impeller outlet pressure profile varying over time are produced. The relationship between radial force evolution and the varying axial-to-spiral vortex structure is analyzed. The radial force change mechanism is revealed. This research provides a scientific

  15. Q-profile evolution and improved core electron confinement in the full current drive operation on Tore Supra

    International Nuclear Information System (INIS)

    Litaudon, X.; Peysson, Y.; Aniel, T.; Huysmans, G.; Imbeaux, F.; Joffrin, E.; Lasalle, J.; Lotte, Ph.; Schunke, B.; Segui, J.; Tresset, G.; Zabiego, M.

    2000-12-01

    The formation of a core region with improved electron confinement is reported in the recent full current drive operation of Tore Supra where the plasma current is sustained with the Lower Hybrid, LH, wave. Current profile evolution and thermal electron transport coefficients are directly assessed using the data of the new fast electron Bremsstrahlung tomography that provides the most accurate determination of the LH current and power deposition profiles. The spontaneous rise of the core electron temperature observed a few seconds after the application of the LH power is ascribed to a bifurcation towards a state of reduced electron transport. The role of the magnetic shear is invoked to partly stabilize the anomalous electron turbulence. The electron temperature transition occurs when the q-profile evolves towards a non-inductive state with a non-monotonic shape i.e. when the magnetic shear is reduced close to zero in the plasma core. The improved core confinement phase is often terminated by a sudden MHD activity when the minimum q approaches two. (authors)

  16. DropBot: An open-source digital microfluidic control system with precise control of electrostatic driving force and instantaneous drop velocity measurement

    International Nuclear Information System (INIS)

    Fobel, Ryan; Fobel, Christian; Wheeler, Aaron R.

    2013-01-01

    We introduce DropBot: an open-source instrument for digital microfluidics (http://microfluidics.utoronto.ca/dropbot). DropBot features two key functionalities for digital microfluidics: (1) real-time monitoring of instantaneous drop velocity (which we propose is a proxy for resistive forces), and (2) application of constant electrostatic driving forces through compensation for amplifier-loading and device capacitance. We anticipate that this system will enhance insight into failure modes and lead to new strategies for improved device reliability, and will be useful for the growing number of users who are adopting digital microfluidics for automated, miniaturized laboratory operation.

  17. [Spatio-temporal change of sand-fixing function and its driving forces in desertification control ecological function area of Hunshandake, China].

    Science.gov (United States)

    Shen, Lu; Tian, Mei-rong; Gao, Ji-xi; Qian, Jin-ping

    2016-01-01

    Soil erosion is an important ecological and environmental problem in Hunshandake Desert, and the sand-fixing function determines the degree of ecological security in the entire region. In order to clarify the situation of windbreak and sand fixation in Hunshandake area, and to guide the prevention and treatment of desertification on regional scale, based on the meteorological and remote sensing data, this paper quantitatively analyzed the temporal and spatial pattern of windbreak and sand fixation ability between 2000-2010 by the revised wind erosion equation (RWEQ) model, meanwhile, the driving forces for each county ( or banner) in the functional zone were analyzed with the method of principal component analysis. The results showed that there was a fluctuation of the sand fixing capacity in Hunshandake over time, generally rendering a decline trend. The coniferous forest and grassland had strong windbreak and sand fixation capacity in unit area among the various land categories. In terms of spatial distribution, the windbreak and sand fixation function in western and southeastern region was weak and needed to be strengthened with ecological restoration efforts. Through the study of the social driving forces of each administrative region in the function zone, there were 3 main social driving forces of soil erosion in the administrative functions: the intensity of input-output, the level of economic development and the level of agriculture-husbandry development.

  18. Photoinduced electron transfer in covalent ruthenium-anthraquinone dyads: relative importance of driving-force, solvent polarity, and donor-bridge energy gap.

    Science.gov (United States)

    Hankache, Jihane; Wenger, Oliver S

    2012-02-28

    Four rigid rod-like molecules comprised of a Ru(bpy)(3)(2+) (bpy = 2,2'-bipyridine) photosensitizer, a 9,10-anthraquinone electron acceptor, and a molecular bridge connecting the two redox partners were synthesized and investigated by optical spectroscopic and electrochemical means. An attempt was made to assess the relative importance of driving-force, solvent polarity, and bridge variation on the rates of photoinduced electron transfer in these molecules. Expectedly, introduction of tert-butyl substituents in the bipyridine ligands of the ruthenium complex and a change in solvent from dichloromethane to acetonitrile lead to a significant acceleration of charge transfer rates. In dichloromethane, photoinduced electron transfer is not competitive with the inherent excited-state deactivation processes of the photosensitizer. In acetonitrile, an increase in driving-force by 0.2 eV through attachment of tert-butyl substituents to the bpy ancillary ligands causes an increase in electron transfer rates by an order of magnitude. Replacement of a p-xylene bridge by a p-dimethoxybenzene spacer entails an acceleration of charge transfer rates by a factor of 3.5. In the dyads from this study, the relative order of importance of individual influences on electron transfer rates is therefore as follows: solvent polarity ≥ driving-force > donor-bridge energy gap.

  19. Local deforestation patterns and their driving forces of tropical dry forest in two municipalities in Southern Oaxaca, Mexico (1985-2006

    Directory of Open Access Journals (Sweden)

    L. Galicia

    2016-11-01

    Full Text Available The tropical dry forest is an ecosystem that is undergoing rapid changes. Although global driving forces behind these changes have been addressed at a local scale, spatio-temporal dynamics are still largely unknown. The main objective of this study was to identify the causes governing the dynamics of changes in land use and land cover in the tropical dry forest in two municipalities in Southern México. Satellite imagery and air photographs were used in a GIS context to produce maps of land use and land cover for 1985, 1995 and 2006. A number of statistical methods (Markov chains, general lineal models and regression tree analysis were applied to identify the proximate and the underlying causes of deforestation, agriculture being the most important one. When agriculture is mainly for self consumption, topographic factors determine its location. Increasing job opportunities in the tourism sector has resulted in the abandonment of agricultural land; consequently, the forest has recovered. Different studies have examined the dynamics of local deforestation and its driving forces in México; however, this study considered both spatial and temporal elements in order to identify the most important underlying driving forces of deforestation and its dynamics at local scale, and also compared two neighboring municipalities.

  20. Evolution of Land Rental Arrangements in Rural Ghana: Evidence ...

    African Journals Online (AJOL)

    zones of Ghana, their varied characters, trends of evolution, and the driving forces .... arrangements have not been given the needed attention in policy, perhaps due to ... markets follows a five-stage trajectory, which can broadly be divided into.

  1. Is ultra-violet radiation the main force shaping molecular evolution of varicella-zoster virus?

    Science.gov (United States)

    2011-01-01

    Background Varicella (chickenpox) exhibits a characteristic epidemiological pattern which is associated with climate. In general, primary infections in tropical regions are comparatively less frequent among children than in temperate regions. This peculiarity regarding varicella-zoster virus (VZV) infection among certain age groups in tropical regions results in increased susceptibility during adulthood in these regions. Moreover, this disease shows a cyclic behavior in which the number of cases increases significantly during winter and spring. This observation further supports the participation of environmental factors in global epidemiology of chickenpox. However, the underlying mechanisms responsible for this distinctive disease behavior are not understood completely. In a recent publication, Philip S. Rice has put forward an interesting hypothesis suggesting that ultra-violet (UV) radiation is the major environmental factor driving the molecular evolution of VZV. Discussion While we welcomed the attempt to explain the mechanisms controlling VZV transmission and distribution, we argue that Rice's hypothesis takes lightly the circulation of the so called "temperate VZV genotypes" in tropical regions and, to certain degree, overlooks the predominance of such lineages in certain non-temperate areas. Here, we further discuss and present new information about the overwhelming dominance of temperate VZV genotypes in Mexico regardless of geographical location and climate. Summary UV radiation does not satisfactorily explain the distribution of VZV genotypes in different tropical and temperate regions of Mexico. Additionally, the cyclic behavior of varicella does not shown significant differences between regions with different climates in the country. More studies should be conducted to identify the factors directly involved in viral spreading. A better understanding of the modes of transmissions exploited by VZV and their effect on viral fitness is likely to facilitate

  2. Is ultra-violet radiation the main force shaping molecular evolution of varicella-zoster virus?

    Directory of Open Access Journals (Sweden)

    Escobar-Gutiérrez Alejandro

    2011-07-01

    Full Text Available Abstract Background Varicella (chickenpox exhibits a characteristic epidemiological pattern which is associated with climate. In general, primary infections in tropical regions are comparatively less frequent among children than in temperate regions. This peculiarity regarding varicella-zoster virus (VZV infection among certain age groups in tropical regions results in increased susceptibility during adulthood in these regions. Moreover, this disease shows a cyclic behavior in which the number of cases increases significantly during winter and spring. This observation further supports the participation of environmental factors in global epidemiology of chickenpox. However, the underlying mechanisms responsible for this distinctive disease behavior are not understood completely. In a recent publication, Philip S. Rice has put forward an interesting hypothesis suggesting that ultra-violet (UV radiation is the major environmental factor driving the molecular evolution of VZV. Discussion While we welcomed the attempt to explain the mechanisms controlling VZV transmission and distribution, we argue that Rice's hypothesis takes lightly the circulation of the so called "temperate VZV genotypes" in tropical regions and, to certain degree, overlooks the predominance of such lineages in certain non-temperate areas. Here, we further discuss and present new information about the overwhelming dominance of temperate VZV genotypes in Mexico regardless of geographical location and climate. Summary UV radiation does not satisfactorily explain the distribution of VZV genotypes in different tropical and temperate regions of Mexico. Additionally, the cyclic behavior of varicella does not shown significant differences between regions with different climates in the country. More studies should be conducted to identify the factors directly involved in viral spreading. A better understanding of the modes of transmissions exploited by VZV and their effect on viral

  3. Structural and electrical evolution of He ion irradiated hydrocarbon films observed by conductive atomic force microscopy

    International Nuclear Information System (INIS)

    Fan, Hongyu; Yang, Deming; Sun, Li; Yang, Qi; Niu, Jinhai; Bi, Zhenhua; Liu, Dongping

    2013-01-01

    Polymer-like hydrocarbon films are irradiated with 100 keV He ion at the fluences of 1.0 × 10 15 –1.0 × 10 17 ions/cm 2 or at the irradiation temperature ranging from 25 to 600 °C. Conductive atomic force microscopy (CAFM) has been used to evaluate the nanoscale electron conducting properties of these irradiated hydrocarbon films. Nanoscale and conducting defects have been formed in the hydrocarbon films irradiated at a relatively high ion fluence (1.0 × 10 17 ions/cm 2 ) or an elevated sample temperature. Analysis indicates that He ion irradiation results in the evolution of polymer-like hydrocarbon into a dense structure containing a large fraction of sp 2 carbon clusters. The sp 2 carbon clusters formed in irradiated hydrocarbon films can contribute to the formation of filament-like conducting channels with a relatively high local field-enhancing factor. Measurements indicate that the growth of nanoscale defects due to He ion irradiation can result in the surface swelling of irradiated hydrocarbon films at a relatively high ion fluences or elevated temperature

  4. Structural and electrical evolution of He ion irradiated hydrocarbon films observed by conductive atomic force microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Fan, Hongyu [School of Physics and Materials Engineering, Dalian Nationalities University, Dalian 116600 (China); Yang, Deming [School of Physics and Materials Engineering, Dalian Nationalities University, Dalian 116600 (China); School of Science, Changchun University of Science and Technology, Changchun, Jilin 130022 (China); Sun, Li [School of Physics and Materials Engineering, Dalian Nationalities University, Dalian 116600 (China); School of Physics, Liaoning Normal University, Dalian 116023 (China); Yang, Qi; Niu, Jinhai; Bi, Zhenhua [School of Physics and Materials Engineering, Dalian Nationalities University, Dalian 116600 (China); Liu, Dongping, E-mail: dongping.liu@dlnu.edu.cn [School of Physics and Materials Engineering, Dalian Nationalities University, Dalian 116600 (China); Fujian Key Laboratory for Plasma and Magnetic Resonance, Department of Electronic Science, Aeronautics, School of Physics and Mechanical and Electrical Engineering, Xiamen University, Xiamen, Fujian 361005 (China)

    2013-10-01

    Polymer-like hydrocarbon films are irradiated with 100 keV He ion at the fluences of 1.0 × 10{sup 15}–1.0 × 10{sup 17} ions/cm{sup 2} or at the irradiation temperature ranging from 25 to 600 °C. Conductive atomic force microscopy (CAFM) has been used to evaluate the nanoscale electron conducting properties of these irradiated hydrocarbon films. Nanoscale and conducting defects have been formed in the hydrocarbon films irradiated at a relatively high ion fluence (1.0 × 10{sup 17} ions/cm{sup 2}) or an elevated sample temperature. Analysis indicates that He ion irradiation results in the evolution of polymer-like hydrocarbon into a dense structure containing a large fraction of sp{sup 2} carbon clusters. The sp{sup 2} carbon clusters formed in irradiated hydrocarbon films can contribute to the formation of filament-like conducting channels with a relatively high local field-enhancing factor. Measurements indicate that the growth of nanoscale defects due to He ion irradiation can result in the surface swelling of irradiated hydrocarbon films at a relatively high ion fluences or elevated temperature.

  5. Analysis of Vehicle Steering and Driving Bifurcation Characteristics

    Directory of Open Access Journals (Sweden)

    Xianbin Wang

    2015-01-01

    Full Text Available The typical method of vehicle steering bifurcation analysis is based on the nonlinear autonomous vehicle model deriving from the classic two degrees of freedom (2DOF linear vehicle model. This method usually neglects the driving effect on steering bifurcation characteristics. However, in the steering and driving combined conditions, the tyre under different driving conditions can provide different lateral force. The steering bifurcation mechanism without the driving effect is not able to fully reveal the vehicle steering and driving bifurcation characteristics. Aiming at the aforementioned problem, this paper analyzed the vehicle steering and driving bifurcation characteristics with the consideration of driving effect. Based on the 5DOF vehicle system dynamics model with the consideration of driving effect, the 7DOF autonomous system model was established. The vehicle steering and driving bifurcation dynamic characteristics were analyzed with different driving mode and driving torque. Taking the front-wheel-drive system as an example, the dynamic evolution process of steering and driving bifurcation was analyzed by phase space, system state variables, power spectral density, and Lyapunov index. The numerical recognition results of chaos were also provided. The research results show that the driving mode and driving torque have the obvious effect on steering and driving bifurcation characteristics.

  6. Polarization-dependent force driving the Eg mode in bismuth under optical excitation: comparison of first-principles theory with ultra-fast x-ray experiments

    Science.gov (United States)

    Fahy, Stephen; Murray, Eamonn

    2015-03-01

    Using first principles electronic structure methods, we calculate the induced force on the Eg (zone centre transverse optical) phonon mode in bismuth immediately after absorption of a ultrafast pulse of polarized light. To compare the results with recent ultra-fast, time-resolved x-ray diffraction experiments, we include the decay of the force due to carrier scattering, as measured in optical Raman scattering experiments, and simulate the optical absorption process, depth-dependent atomic driving forces, and x-ray diffraction in the experimental geometry. We find excellent agreement between the theoretical predictions and the observed oscillations of the x-ray diffraction signal, indicating that first-principles theory of optical absorption is well suited to the calculation of initial atomic driving forces in photo-excited materials following ultrafast excitation. This work is supported by Science Foundation Ireland (Grant No. 12/IA/1601) and EU Commission under the Marie Curie Incoming International Fellowships (Grant No. PIIF-GA-2012-329695).

  7. Self-consistent modeling of the dynamic evolution of magnetic island growth in the presence of stabilizing electron-cyclotron current drive

    International Nuclear Information System (INIS)

    Chatziantonaki, Ioanna; Tsironis, Christos; Isliker, Heinz; Vlahos, Loukas

    2013-01-01

    The most promising technique for the control of neoclassical tearing modes in tokamak experiments is the compensation of the missing bootstrap current with an electron-cyclotron current drive (ECCD). In this frame, the dynamics of magnetic islands has been studied extensively in terms of the modified Rutherford equation (MRE), including the presence of a current drive, either analytically described or computed by numerical methods. In this article, a self-consistent model for the dynamic evolution of the magnetic island and the driven current is derived, which takes into account the island's magnetic topology and its effect on the current drive. The model combines the MRE with a ray-tracing approach to electron-cyclotron wave-propagation and absorption. Numerical results exhibit a decrease in the time required for complete stabilization with respect to the conventional computation (not taking into account the island geometry), which increases by increasing the initial island size and radial misalignment of the deposition. (paper)

  8. Self-consistent modeling of the dynamic evolution of magnetic island growth in the presence of stabilizing electron-cyclotron current drive

    Science.gov (United States)

    Chatziantonaki, Ioanna; Tsironis, Christos; Isliker, Heinz; Vlahos, Loukas

    2013-11-01

    The most promising technique for the control of neoclassical tearing modes in tokamak experiments is the compensation of the missing bootstrap current with an electron-cyclotron current drive (ECCD). In this frame, the dynamics of magnetic islands has been studied extensively in terms of the modified Rutherford equation (MRE), including the presence of a current drive, either analytically described or computed by numerical methods. In this article, a self-consistent model for the dynamic evolution of the magnetic island and the driven current is derived, which takes into account the island's magnetic topology and its effect on the current drive. The model combines the MRE with a ray-tracing approach to electron-cyclotron wave-propagation and absorption. Numerical results exhibit a decrease in the time required for complete stabilization with respect to the conventional computation (not taking into account the island geometry), which increases by increasing the initial island size and radial misalignment of the deposition.

  9. Chiral three-nucleon forces and the evolution of correlations along the oxygen isotopic chain

    Science.gov (United States)

    Cipollone, A.; Barbieri, C.; Navrátil, P.

    2015-07-01

    Background: Three-nucleon forces (3NFs) have nontrivial implications on the evolution of correlations at extreme proton-neutron asymmetries. Recent ab initio calculations show that leading-order chiral interactions are crucial to obtain the correct binding energies and neutron driplines along the O, N, and F chains [A. Cipollone, C. Barbieri, and P. Navrátil, Phys. Rev. Lett. 111, 062501 (2013), 10.1103/PhysRevLett.111.062501]. Purpose: Here we discuss the impact of 3NFs along the oxygen chain for other quantities of interest, such has the spectral distribution for attachment and removal of a nucleon, spectroscopic factors, and radii. The objective is to better delineate the general effects of 3NFs on nuclear correlations. Methods: We employ self-consistent Green's function (SCGF) theory which allows a comprehensive calculation of the single-particle spectral function. For the closed subshell isotopes, 14O, 16O, 22O, 24O, and 28O, we perform calculations with the Dyson-ADC(3) method, which is fully nonperturbative and is the state of the art for both nuclear physics and quantum chemistry applications. The remaining open-shell isotopes are studied using the newly developed Gorkov-SCGF formalism up to second order. Results: We produce complete plots for the spectral distributions. The spectroscopic factors for the dominant quasiparticle peaks are found to depend very little on the leading-order (NNLO) chiral 3NFs. The latter have small impact on the calculated matter radii, which, however, are consistently obtained smaller than experiment. Similarly, single-particle spectra tend to be too spread with respect to the experiment. This effect might hinder, to some extent, the onset of correlations and screen the quenching of calculated spectroscopic factors. The most important effect of 3NFs is thus the fine tuning of the energies for the dominant quasiparticle states, which governs the shell evolution and the position of driplines. Conclusions: Although present chiral

  10. Evolution of Wigner function in laser process under the action of linear resonance force and its application

    Science.gov (United States)

    Dao-ming, Lu

    2018-05-01

    The negativity of Wigner function (WF) is one of the important symbols of non-classical properties of light field. Therefore, it is of great significance to study the evolution of WF in dissipative process. The evolution formula of WF in laser process under the action of linear resonance force is given by virtue of thermo entangled state representation and the technique of integration within an ordered product of operator. As its application, the evolution of WF of thermal field and that of single-photon-added coherent state are discussed. The results show that the WF of thermal field maintains its original character. On the other hand, the negative region size and the depth of negativity of WF of single- photon-added coherent state decrease until it vanishes with dissipation. This shows that the non-classical property of single-photon-added coherent state is weakened, until it disappears with dissipation time increasing.

  11. Beyond barriers – A case study on driving forces for improved energy efficiency in the foundry industries in Finland, France, Germany, Italy, Poland, Spain, and Sweden

    International Nuclear Information System (INIS)

    Thollander, Patrik; Backlund, Sandra; Trianni, Andrea; Cagno, Enrico

    2013-01-01

    Highlights: • Results are based on a questionnaire in the European foundry industry. • The energy efficiency potential is assed to be 7.5% of the total energy use. • Most important drivers to and barriers for energy efficiency are financial followed by organizational. • EPC is used among 23% of the foundries, third party financing among 12%. • Large energy management improvement potentials are uncovered. - Abstract: Energy management plays an important role in the transformation of industrial energy systems towards improved energy efficiency and increased sustainability. This paper aims to study driving forces for improved energy efficiency in some European energy-intensive foundry industries. The investigation has been conducted as a multiple case study involving 65 foundries located in Finland, France, Germany, Italy, Poland, Spain, and Sweden. The most relevant perceived driving forces were found to be financially related, followed by organizational driving forces. Nevertheless, some differences can be appreciated according to the firm’s size and country. Almost half of the studied foundries lack a long-term energy strategy, about one-fourth stated that they have used Energy Performance Contracting (EPC), and only approximately one in ten foundries have used Third Party Financing (TPF). Among the studied foundries, three out of five have conducted an energy audit. On average, the energy saving potential according to the respondents is stated to be 7.5%. In conclusion, energy management in the European foundry industry, despite increasing energy prices and extensive energy policy actions taken by the EU, still seems to have great improvement potential, calling for future research and policy actions in the field

  12. The effect of electric field geometry on the performance of electromembrane extraction systems: Footprints of a third driving force along with migration and diffusion

    Energy Technology Data Exchange (ETDEWEB)

    Moazami, Hamid Reza [School of Physics and Accelerators, NSTRI, P. O. Box, 11365-8486, Tehran (Iran, Islamic Republic of); Hosseiny Davarani, Saied Saeed, E-mail: ss-hosseiny@sbu.ac.ir [Faculty of Chemistry, Shahid Beheshti University, G. C., 1983963113, Evin, Tehran (Iran, Islamic Republic of); Mohammadi, Jamil; Nojavan, Saeed [Faculty of Chemistry, Shahid Beheshti University, G. C., 1983963113, Evin, Tehran (Iran, Islamic Republic of); Abrari, Masoud [Laser and Plasma Research Institute, Shahid Beheshti University, G. C., 1983963113, Evin, Tehran (Iran, Islamic Republic of)

    2015-09-03

    The distribution of electric field vectors was first calculated for electromembrane extraction (EME) systems in classical and cylindrical electrode geometries. The results showed that supported liquid membrane (SLM) has a general field amplifying effect due to its lower dielectric constant in comparison with aqueous donor/acceptor solutions. The calculated norms of the electric field vector showed that a DC voltage of 50 V can create huge electric field strengths up to 64 kV m{sup −1} and 111 kV m{sup −1} in classical and cylindrical geometries respectively. In both cases, the electric field strength reached its peak value on the inner wall of the SLM. In the case of classical geometry, the field strength was a function of the polar position of the SLM whereas the field strength in cylindrical geometry was angularly uniform. In order to investigate the effect of the electrode geometry on the performance of real EME systems, the analysis was carried out in three different geometries including classical, helical and cylindrical arrangements using naproxen and sodium diclofenac as the model analytes. Despite higher field strength and extended cross sectional area, the helical and cylindrical geometries gave lower recoveries with respect to the classical EME. The observed decline of the signal was proved to be against the relations governing migration and diffusion processes, which means that a third driving force is involved in EME. The third driving force is the interaction between the radially inhomogeneous electric field and the analyte in its neutral form. - Highlights: • Electric field vectors have been calculated in EME systems. • A new driving force has been proposed in EME systems. • EME can be theoretically applied to nonionic polarizable analytes.

  13. The effect of electric field geometry on the performance of electromembrane extraction systems: Footprints of a third driving force along with migration and diffusion

    International Nuclear Information System (INIS)

    Moazami, Hamid Reza; Hosseiny Davarani, Saied Saeed; Mohammadi, Jamil; Nojavan, Saeed; Abrari, Masoud

    2015-01-01

    The distribution of electric field vectors was first calculated for electromembrane extraction (EME) systems in classical and cylindrical electrode geometries. The results showed that supported liquid membrane (SLM) has a general field amplifying effect due to its lower dielectric constant in comparison with aqueous donor/acceptor solutions. The calculated norms of the electric field vector showed that a DC voltage of 50 V can create huge electric field strengths up to 64 kV m −1 and 111 kV m −1 in classical and cylindrical geometries respectively. In both cases, the electric field strength reached its peak value on the inner wall of the SLM. In the case of classical geometry, the field strength was a function of the polar position of the SLM whereas the field strength in cylindrical geometry was angularly uniform. In order to investigate the effect of the electrode geometry on the performance of real EME systems, the analysis was carried out in three different geometries including classical, helical and cylindrical arrangements using naproxen and sodium diclofenac as the model analytes. Despite higher field strength and extended cross sectional area, the helical and cylindrical geometries gave lower recoveries with respect to the classical EME. The observed decline of the signal was proved to be against the relations governing migration and diffusion processes, which means that a third driving force is involved in EME. The third driving force is the interaction between the radially inhomogeneous electric field and the analyte in its neutral form. - Highlights: • Electric field vectors have been calculated in EME systems. • A new driving force has been proposed in EME systems. • EME can be theoretically applied to nonionic polarizable analytes.

  14. Using geoinformatics and cultural anthropology to identify links between land change, driving forces and actors in the Okavango catchment

    Science.gov (United States)

    Röder, Achim; Stellmes, Marion; Pröpper, Michael; Schneibel, Anne

    2015-04-01

    intensive uses, although the same processes are likely to occur in parts of the Okavango region in the future. Literature: Banwart, S. (2011). "Save our soils." Nature 474: 151-152. Bürgi, M., A. M. Hersperger, et al. (2004). "Driving forces of landscape change - current and new directions." Landscape Ecology 19: 857-868. Butchart, S. H. M., M. Walpole, et al. (2010). "Global Biodiversity: Indicators of Recent Declines." Science 328(5982): 1164-1168. Ellis, E. C. and N. Ramankutty (2008). "Putting people in the map: anthropogenic biomes of the world." Frontiers in Ecology and the Environment 6(8): 439-447. Foley, J. A., R. Defries, et al. (2005). "Global consequences of land use." Science 309(5734): 570-574. Geist, H. J. and E. F. Lambin (2002). "Proximate causes and underlying driving forces of tropical deforestation." BioScience 52(2): 143-150. Haub, C. (2012) World Population Data Sheet. World Population Hein, L., K. van Koppen, et al. (2006). "Spatial scales, stakeholders and the valuation of ecosystem services." Ecological Economics 57: 209-228. Hersperger, A. M., M.-P. Gennaio, et al. (2010). "Linking land change with driving forces and actors: four conceptual models." Ecology and Society 15(4): 1-17. Huang, C., L. S. Davis, et al. (2002). "An assessment of support vector machines for land cover classification." International Journal of Remote Sensing 23(4): 725-749. IPCC (2013). Climate Change 2013: The Physical Science Basis. Contribution of Working Group I to the Fifth Assessment Report of the Intergovernmental Panel on Climate Change. T. F. Stocker, G. Qin, G.-K. Plattneret al. Cambridge, Cambridge University Press. Jönsson, P. and L. Eklundh (2004). "TIMESAT - a program for analysing time-series of satellite sensor data." Computers and Geosciences 30(833-845). Kowalski, B., N. Azebaze, et al. (2013). "Mashare - The People." Biodiversity & Ecology 5: 121-128. Lal, R. (2013). "Climate-strategic agriculture and the water-soil-waste nexus." Journal of Plant

  15. Smart management - Driving forces and conditions for the development of advanced electricity networks; Smart ledning - Drivkrafter och foerutsaettningar foer utveckling av avancerade elnaet

    Energy Technology Data Exchange (ETDEWEB)

    Larsson, Oerjan; Staahl, Benjamin (Blue Inst., Stockholm (Sweden))

    2011-02-15

    This report describes the development of Intelligent Networks, or Smart Grids. It is divided into two sections. The first section highlights the basics of what is called 'smart' grid technology, what the underlying driving forces are and how the conditions for market looks like. It also depicts the impact on consumers, emerging business logics and ongoing investment and incentives in the world. The first part ends with an operator map of the market. The second part takes a closer look on some key areas and includes a simple reminder of technology related to smart grids

  16. First-principles calculation of the polarization-dependent force driving the Eg mode in bismuth under optical excitation.

    Science.gov (United States)

    Murray, Eamonn; Fahy, Stephen

    2014-03-01

    Using first principles electronic structure methods, we calculate the induced force on the Eg (zone centre transverse optical) phonon mode in bismuth immediately after absorption of polarized light. When radiation with polarization perpendicular to the c-axis is absorbed in bismuth, the distribution of excited electrons and holes breaks the three-fold rotational symmetry and leads to a net force on the atoms in the direction perpendicular to the axis. We calculate the initial excited electronic distribution as a function of photon energy and polarization and find the resulting transverse and longitudinal forces experienced by the atoms. Using the measured, temperature-dependent rate of decay of the transverse force[2], we predict the approximate amplitude of induced atomic motion in the Eg mode as a function of temperature and optical fluence. This work is supported by Science Foundation Ireland and a Marie Curie International Incoming Fellowship.

  17. Driving Forces of Dynamic Changes in Soil Erosion in the Dahei Mountain Ecological Restoration Area of Northern China Based on GIS and RS.

    Science.gov (United States)

    Li, Xiao; Niu, Xiang; Wang, Bing; Gao, Peng; Liu, Yu

    2016-01-01

    Dynamic change in soil erosion is an important focus of regional ecological restoration research. Here, the dynamic changes of soil erosion and its driving forces in the Dahei Mountain ecological restoration area of northern China were analyzed by LANDSAT TM remote sensing captured via geographic information system (GIS) technologies during three typical periods in 2004, 2008 and 2013. The results showed the following: (1) a decrease in intensive erosion and moderate erosion areas, as well as an increase in light erosion areas, was observed during two periods: one from 2004 to 2008 and the other from 2008 to 2013. (2) Between 2004 and 2008, the variation in the range of slight erosion was the largest (24.28%), followed by light erosion and intensive erosion; between 2008 and 2013, the variation in the range of intensive erosion area was the largest (9.89%), followed by slight erosion and moderate erosion. (3) Socioeconomic impact, accompanied by natural environmental factors, was the main driving force underlying the change in soil erosion within the ecological restoration area. In particular, the socioeconomic factors of per capita forest area and land reclamation rate, as well as the natural environmental factor of terrain slope, significantly influenced soil erosion changes within the ecological restoration area.

  18. Structure and relative importance of ponderomotive forces and current drive generated by converted fast waves in pre-heated low aspect ratio tokamaks

    Energy Technology Data Exchange (ETDEWEB)

    Cuperman, S.; Bruma, C.; Komoshvili, K

    2003-05-12

    The generation in low aspect ratio tokamaks (LARTs) of ponderomotive forces and non-inductive current drive by the resonant fast wave-plasma interaction with mode conversion to kinetic Alfven waves (KAWs) and subsequent deposition, mainly by resonant electron Landau damping, is considered. The calculations follow the rigorous solution of the full wave equations upon using a dielectric tensor operator consisting of (i) a parallel conductivity including both kinetic effects (collisionless Landau damping on passing electrons) and collisional damping on both trapped electrons and passing electrons+ions and (ii) perpendicular components provided by the resistive two-fluid model equations. The fast waves are launched by an antenna located on the low field side and extending {+-}45 deg. about the equatorial plane. A parametric investigation of the structure and importance of the various components of the ponderomotive forces and current drive generated in START-like plasmas is carried out and their suitability for supplementing the required non-rf toroidal equilibrium current is demonstrated.

  19. Analyzing the driving forces behind CO2 emissions and reduction strategies for energy-intensive sectors in Taiwan, 1996–2006

    International Nuclear Information System (INIS)

    Huang, Yun-Hsun; Wu, Jung-Hua

    2013-01-01

    Between 1996 and 2006, CO 2 emissions in Taiwan increased by approximately 60%, with the industrial sector accounting for 50% of that increase. Among all industrial sectors, iron and steel, petrochemicals, electronics, textiles, pulp and paper and cement accounted for approximately three-quarters of the total industrial CO 2 emissions. Identifying the driving forces behind increased CO 2 emissions in these six sectors could be valuable for the development of effective environmental policy. This study used two-tier KLEM input–output structural decomposition analysis (I-O SDA) to analyze the factors that lead to changes in CO 2 emissions. Empirical results obtained in Taiwan reveal that increased exports level and elevated domestic autonomous final demand level were the main reasons for increases in CO 2 emissions. Technological changes in materials and labor tended to decrease CO 2 emissions, while the power generation mix contributed significantly to the increase. Relevant strategies for reducing CO 2 emissions from energy-intensive sectors are also highlighted. - Highlights: • Identifying the driving forces behind increased CO 2 emissions is important. • This study uses two-tier KLEM I-O SDA to analyze the changes in CO 2 emissions. • Three issues are identified to achieve future CO 2 emissions reduction in Taiwan

  20. Driving forces and barriers to improved energy performance of buildings: an analysis of energy performance of Swedish buildings, 2000-2006

    Energy Technology Data Exchange (ETDEWEB)

    Fuglseth, Bente Beckstroem

    2008-06-15

    The building sector is responsible for a substantial part of energy use and green house gas emissions in Europe. This report explores driving forces and barriers to improved energy performance of buildings, using the Swedish building sector as a case. The development of energy performance of buildings in Sweden from 2000 until 2006 is explored by applying a threefold understanding of energy performance of buildings: substitution from fossil fuels to renewable energy, conversion from electrical heating to thermal energy and reduction in energy demand. Three explanatory approaches are used to analyse driving forces and barriers to improved energy performance: the techno-economic approach stresses the physical aspects of infrastructure and technologies, the institutional approach emphasizes the role of institutional factors, while the regulative approach focuses on formal rules and laws. The study concludes that all factors have promoted substitution of fossil fuels with renewable energy, while they have prevented conversion from electrical heating to thermal energy and reduction in energy demand. (author). 95 refs

  1. A piezo motor based on a new principle with high output force, rigidity and integrity: The Tuna Drive

    Science.gov (United States)

    Liu, Xiaolong; Lu, Qingyou

    2012-11-01

    We present a linear piezoelectric motor as simple as one piezoelectric scanner tube (PST) spring-clamping a central shaft at both ends with roughly equal clamping forces. The clamping points are aligned with ±X electrodes at one end and ±Y electrodes at the other end. Thus, the ±X (or ±Y) push-pull motions of the PST can cause the push-pull motions of the clamping points on the shaft (called push-pull rubbing), which reduces the total dynamic friction force at one (or the other) end of the PST. This new piezo motor advances one step by fast push-pull rubbing at one end while slowly retracting the PST followed by fast push-pull rubbing at the other end while slowly elongating the PST. Apart from the obvious advantages of simplicity, rigidity, integrity, etc., we will also show that this motor can produce a large output force, which we believe is because of the huge drop of the clamping friction force when the push-pull rubbing occurs.

  2. Up-regulation of Rho/ROCK signaling in sarcoma cells drives invasion and increased generation of protrusive forces

    Czech Academy of Sciences Publication Activity Database

    Rosel, D.; Brabek, J.; Tolde, O.; Mierke, C.T.; Zitterbart, D.P.; Raupach, C.; Bicanova, K.; Kollmannsberger, P.; Pánková, D.; Veselý, Pavel; Folk, P.; Fabry, B.

    2008-01-01

    Roč. 6, č. 9 (2008), s. 1410-1420 ISSN 1541-7786 Institutional research plan: CEZ:AV0Z50520514 Keywords : Rho kinase ROCK * traction force microscopy * ameboid invasion Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 4.533, year: 2008

  3. Varieties of flood risk governance in Europe: How do countries respond to driving forces and what explains institutional change?

    NARCIS (Netherlands)

    Wiering, M.A.; Kaufmann, M.; Mees, H.; Schellenberger, T.; Ganzevoort, W.; Hegger, D.L.T.; Larrue, C.; Matczak, P.

    2017-01-01

    Floods are challenging the resilience of societies all over the world. In many countries there are discussions on diversifying the strategies for flood risk management, which implies some sort of policy change. To understand the possibilities of such change, a thorough understanding of the forces of

  4. The Conflicting Forces Driving Future Avionics Acquisition (Les Arguments Contradictoires pour les Futurs Achats d’Equipements d’Avionique)

    Science.gov (United States)

    1991-09-01

    Sep 1983 "Reliability Parameter of Additive Plated Through Hoics," William E. Greiner , Kollmorgen Corporation, 1rAnnual "Guidelines for Surface Mounting...Militare Etat-Major delIs Force Adienne Ufficio del Delegato Nazionaic all*AGARD Quartier Reine Elisabeth Aeroporto Pratica di Mare Rue d’Evere, 1140

  5. The asymmetric evolution of the Colombian Eastern Cordillera. Tectonic inheritance or climatic forcing? New evidence from thermochronology and sedimentology

    Science.gov (United States)

    Ramirez-Arias, Juan Carlos; Mora, Andrés; Rubiano, Jorge; Duddy, Ian; Parra, Mauricio; Moreno, Nestor; Stockli, Daniel; Casallas, Wilson

    2012-11-01

    New thermochronological data, facies, paleocurrents and provenance allow us to refine the chronology of deformation in the central segment of the Colombian Eastern Cordillera. Based on a new extensive AFT dataset, we document the spatial evolution of active deformation, from the axial zone of the Eastern Cordillera at about 50 Ma in to active growth of the frontal thin skinned structures in Late Miocene time. Paleocurrents allow us to push backwards into the Middle to Early Late-Miocene the emergence of the easternmost frontal thrust; whereas careful assessment of exposure gates tied to AFT data enable to refine the unroofing history for Eocene to Miocene times. Based on that, we produced a kinematically restored cross section with higher resolution than previous assessments. Using these datasets, we compare the evolution of the central segment of the Eastern Cordillera in this region with the evolution of adjacent areas in the context of climatic forcing of orogenic evolution. We find that in this region and, in the Eastern Cordillera in general, tectonic inheritance and transpression exert an initial dominant control on the initial orogen asymmetry, which is later enhanced due to an orographically-focused erosion. We therefore suggest that it is not climate alone the factor controlling orogenic asymmetry in the Eastern Cordillera of Colombia.

  6. Combat Pair: The Evolution of Air Force-Navy Integration in Strike Warfare

    National Research Council Canada - National Science Library

    Lambeth, Benjamin

    2007-01-01

    This report documents the exceptional cross-service harmony that the U.S. Air Force and U.S. Navy have steadily developed in their conduct of integrated strike operations since the first Persian Gulf War in 1991...

  7. Tectonics, orbital forcing, global climate change, and human evolution in Africa: introduction to the African paleoclimate special volume.

    Science.gov (United States)

    Maslin, Mark A; Christensen, Beth

    2007-11-01

    The late Cenozoic climate of Africa is a critical component for understanding human evolution. African climate is controlled by major tectonic changes, global climate transitions, and local variations in orbital forcing. We introduce the special African Paleoclimate Issue of the Journal of Human Evolution by providing a background for and synthesis of the latest work relating to the environmental context for human evolution. Records presented in this special issue suggest that the regional tectonics, appearance of C(4) plants in East Africa, and late Cenozoic global cooling combined to produce a long-term drying trend in East Africa. Of particular importance is the uplift associated with the East African Rift Valley formation, which altered wind flow patterns from a more zonal to more meridinal direction. Results in this volume suggest a marked difference in the climate history of southern and eastern Africa, though both are clearly influenced by the major global climate thresholds crossed in the last 3 million years. Papers in this volume present lake, speleothem, and marine paleoclimate records showing that the East African long-term drying trend is punctuated by episodes of short, alternating periods of extreme wetness and aridity. These periods of extreme climate variability are characterized by the precession-forced appearance and disappearance of large, deep lakes in the East African Rift Valley and paralleled by low and high wind-driven dust loads reaching the adjacent ocean basins. Dating of these records show that over the last 3 million years such periods only occur at the times of major global climatic transitions, such as the intensification of Northern Hemisphere Glaciation (2.7-2.5 Ma), intensification of the Walker Circulation (1.9-1.7 Ma), and the Mid-Pleistocene Revolution (1-0.7 Ma). Authors in this volume suggest this onset occurs as high latitude forcing in both Hemispheres compresses the Intertropical Convergence Zone so that East Africa

  8. Feed-backs among inbreeding, inbreeding depression in sperm traits, and sperm competition can drive evolution of costly polyandry.

    Science.gov (United States)

    Bocedi, Greta; Reid, Jane M

    2017-12-01

    Ongoing ambitions are to understand the evolution of costly polyandry and its consequences for species ecology and evolution. Emerging patterns could stem from feed-back dynamics between the evolving mating system and its genetic environment, defined by interactions among kin including inbreeding. However, such feed-backs are rarely considered in nonselfing systems. We use a genetically explicit model to demonstrate a mechanism by which inbreeding depression can select for polyandry to mitigate the negative consequences of mating with inbred males, rather than to avoid inbreeding, and to elucidate underlying feed-backs. Specifically, given inbreeding depression in sperm traits, costly polyandry evolved to ensure female fertility, without requiring explicit inbreeding avoidance. Resulting sperm competition caused evolution of sperm traits and further mitigated the negative effect of inbreeding depression on female fertility. The evolving mating system fed back to decrease population-wide homozygosity, and hence inbreeding. However, the net overall decrease was small due to compound effects on the variances in sex-specific reproductive success and paternity skew. Purging of deleterious mutations did not eliminate inbreeding depression in sperm traits or hence selection for polyandry. Overall, our model illustrates that polyandry evolution, both directly and through sperm competition, might facilitate evolutionary rescue for populations experiencing sudden increases in inbreeding. © 2017 The Author(s). Evolution © 2017 The Society for the Study of Evolution.

  9. From Conception to Birth: The Forces Responsible for AFCyber’s Evolution

    Science.gov (United States)

    2014-06-01

    key  technologies” from the F‐35. A fire‐control array radar system,  thrust ‐ vectoring  jet  nozzle , electro‐   11    Cyber Policy and Organizations: USG...EVOLUTION BY JOHANNES MOORE A THESIS PRESENTED TO THE FACULTY OF THE SCHOOL OF ADVANCED AIR AND SPACE STUDIES FOR COMPLETION OF GRADUATION...contribute in concept and execution toward joint operations. This thesis describes in unprecedented detail the evolution of AFCYBER, identifies the

  10. Orbital-scale nonlinear response of East Asian summer monsoon to its potential driving forces in the late Quaternary

    Science.gov (United States)

    Yi, Liang; Shi, Zhengguo; Tan, Liangcheng; Deng, Chenglong

    2018-03-01

    We conducted a statistical study to characterize the nonlinear response of the East Asian summer monsoon (EASM) to its potential forcing factors over the last 260 ka on orbital timescales. We find that both variation in solar insolation and global ice volume were responsible for the nonlinear forcing of orbital-scale monsoonal variations, accounting for 80% of the total variance. Specifically, EASM records with dominated precession variance exhibit a more sensitive response to changes in solar insolation during intervals of enhanced monsoon strength, but are less sensitive during intervals of reduced monsoon strength. In the case of global ice volume with 100-ka variance, this difference is not one of sensitivity but rather a difference in baseline conditions, such as the relative areas of land and sea which affected the land-sea thermal gradient. We therefore suggest that EASM records with dominated precession variance recorded the signal of a shift in the location of the Inter-tropical Convergence Zone, and the associated changes in the incidence of torrential rainfall; while for proxies with dominated 100-ka variance, it recorded changes in the land-sea thermal gradient via its effects on non-torrential precipitation.

  11. Spontaneous formation of small unilamellar vesicles by pH jump: A pH gradient across the bilayer membrane as the driving force

    International Nuclear Information System (INIS)

    Hauser, H.; Mantsch, H.H.; Casal, H.L.

    1990-01-01

    31 P NMR and infrared spectroscopic methods have been used to study the formation of small unilamellar vesicles by the pH-jump method. It is shown that increasing the pH of different lamellar phospholipid dispersions (phosphatidic acids and phosphatidylserines) induces a pH gradient. This pH gradient is estimated to be 4 ± 1 pH units, and its direction is such that the inner monolayer of the vesicles is at lower pH. There is spectroscopic evidence for tighter packing of the lipid hydrocarbon chains in the inner monolayer, probably due to the constraints imposed by the high curvature of the small vesicles formed. These results are discussed in terms of the driving force of the spontaneous vesiculation

  12. Dehydrogenation Kinetics and Modeling Studies of MgH2 Enhanced by Transition Metal Oxide Catalysts Using Constant Pressure Thermodynamic Driving Forces

    Directory of Open Access Journals (Sweden)

    Saidi Temitope Sabitu

    2012-06-01

    Full Text Available The influence of transition metal oxide catalysts (ZrO2, CeO2, Fe3O4 and Nb2O5 on the hydrogen desorption kinetics of MgH2 was investigated using constant pressure thermodynamic driving forces in which the ratio of the equilibrium plateau pressure (pm to the opposing plateau (pop was the same in all the reactions studied. The results showed Nb2O5 to be vastly superior to other catalysts for improving the thermodynamics and kinetics of MgH2. The modeling studies showed reaction at the phase boundary to be likely process controlling the reaction rates of all the systems studied.

  13. Driving forces of redistribution of elements during quasicrystalline phase formation under heating of mechanically alloyed Al65Cu23Fe12 powder

    Science.gov (United States)

    Tcherdyntsev, V. V.; Kaloshkin, S. D.; Shelekhov, E. V.; Principi, G.; Rodin, A. O.

    2008-02-01

    Al65Cu23Fe12 alloys were prepared by ball milling of the elemental powders mixture. Phase and structural transformations at heating of as-milled powders were investigated by X-ray diffraction analysis. Precision analysis of Mössbauer spectra was performed to check the adequacy of the fitting of X-ray diffraction patterns. The results were compared with the data of differential scanning and solution calorimetry, as well as with the thermodynamic literature data, in order to estimate the driving forces of redistribution of elements that preceded the formation of single-phase quasicrystalline structure. The heat of elements mixing, which is positive for Cu-Fe system and negative for Al-Fe and Al-Cu systems, was supposed to be a decisive factor for phase transformations during heating of the alloy. The correlation between sequence of phase transformations during heating and the thermodynamic data was discussed and the scheme describing phase transformations observed was proposed.

  14. Bimodal atomic force microscopy driving the higher eigenmode in frequency-modulation mode: Implementation, advantages, disadvantages and comparison to the open-loop case.

    Science.gov (United States)

    Ebeling, Daniel; Solares, Santiago D

    2013-01-01

    We present an overview of the bimodal amplitude-frequency-modulation (AM-FM) imaging mode of atomic force microscopy (AFM), whereby the fundamental eigenmode is driven by using the amplitude-modulation technique (AM-AFM) while a higher eigenmode is driven by using either the constant-excitation or the constant-amplitude variant of the frequency-modulation (FM-AFM) technique. We also offer a comparison to the original bimodal AFM method, in which the higher eigenmode is driven with constant frequency and constant excitation amplitude. General as well as particular characteristics of the different driving schemes are highlighted from theoretical and experimental points of view, revealing the advantages and disadvantages of each. This study provides information and guidelines that can be useful in selecting the most appropriate operation mode to characterize different samples in the most efficient and reliable way.

  15. Gibbs energy modelling of the driving forces and calculation of the fcc/hcp martensitic transformation temperatures in Fe-Mn and Fe-Mn-Si alloys

    International Nuclear Information System (INIS)

    Cotes, S.; Fernandez Guillermet, A.; Sade, M.

    1999-01-01

    Very recent, accurate dilatometric measurements of the fcc hcp martensitic transformation (MT) temperatures are used to develop a new thermodynamic description of the fcc and hcp phases in the Fe-Mn-Si system, based on phenomenological models for the Gibbs energy function. The composition dependence of the driving forces for the fcc→hcp and the hcp→fcc MTs is established. Detailed calculations of the MT temperatures are reported, which are used to investigate the systematic effects of Si additions upon the MT temperatures of Fe-Mn alloys. A critical comparison with one of the most recent thermodynamic analyses of the Fe-Mn-Si system, which is due to Forsberg and Agren, is also presented. (orig.)

  16. Analysis of Urban-Rural Land-Use Change during 1995-2006 and Its Policy Dimensional Driving Forces in Chongqing, China

    Directory of Open Access Journals (Sweden)

    Guihua Dong

    2008-02-01

    Full Text Available This paper analyzes the urban-rural land-use change of Chongqing and its policydimensional driving forces from 1995 to 2006, using high-resolution Landsat TM(Thematic Mapper data of 1995, 2000 and 2006, and socio-economic data from bothresearch institutes and government departments. The outcomes indicated that urban-ruralland-use change in Chongqing can be characterized by two major trends: First, thenon-agricultural land increased substantially from 1995 to 2006, thus causing agriculturalland especially farmland to decrease continuously. Second, the aggregation index of urbansettlements and rural settlements shows that local urban-rural development experienced aprocess of changing from aggregation (1995-2000 to decentralization (2000-2006.Chongqing is a special area getting immersed in many important policies, which includethe establishment of the municipality directly under the Central Government, the buildingof Three Gorges Dam Project, the Western China Development Program and theGrain-for-Green Programme, and bring about tremendous influences on its land-usechange. By analyzing Chongqing’s land-use change and its policy driving forces, someimplications for its new policy of ‘Urban-rural Integrated Reform’ are obtained. That ismore attentions need to be paid to curbing excessive and idle rural housing andconsolidating rural construction land, and to laying out a scientific land-use plan for its rural areas taking such rural land-use issues as farmland occupation and rural housing landmanagement into accounts, so as to coordinate and balance the urban-rural development.

  17. Disentangling phylogenetic constraints from selective forces in the evolution of trematode transmission stages

    NARCIS (Netherlands)

    Koehler, A.V.; Brown, B.; Poulin, R.; Thieltges, D.W.; Fredensborg, B.L.

    2012-01-01

    The transmission stages of parasites are key determinants of parasite fitness, but they also incur huge mortality. Yet the selective forces shaping the sizes of transmission stages remain poorly understood. We ran a comparative analysis of interspecific variation in the size of transmission stages

  18. United theory of biological evolution: Disaster-forced evolution through Supernova, radioactive ash fall-outs, genome instability, and mass extinctions

    Directory of Open Access Journals (Sweden)

    Toshikazu Ebisuzaki

    2015-01-01

    Full Text Available We present the disaster-forced biological evolution model as a general framework that includes Darwinian “phylogenic gradualism”, Eldredge-Gould's “punctuated equilibrium”, mass extinctions, and allopatric, parapatric, and sympatric speciation. It describes how reproductive isolation of organisms is established through global disasters due to supernova encounters and local disasters due to radioactive volcanic ash fall-outs by continental alkaline volcanism. Our new evolution model uniquely highlights three major factors of disaster-forced speciation: enhanced mutation rate by higher natural radiation level, smaller population size, and shrunken habitat size (i.e., isolation among the individual populations. We developed a mathematical model describing speciation of a half-isolated group from a parental group, taking into account the population size (Ne, immigration rate (m, and mutation rate (μ. The model gives a quantitative estimate of the speciation, which is consistent with the observations of speciation speed. For example, the speciation takes at least 105 generations, if mutation rate is less than 10−3 per generation per individual. This result is consistent with the previous studies, in which μ is assumed to be 10−3–10−5. On the other hand, the speciation is much faster (less than 105 generations for the case that μ is as large as 0.1 in parapatric conditions (m < μ. Even a sympatric (m ~ 1 speciation can occur within 103 generations, if mutation rate is very high (μ ~ 1 mutation per individual per generation, and if Ne < 20–30. Such a high mutation rate is possible during global disasters due to supernova encounters and local disasters due to radioactive ash fall-outs. They raise natural radiation level by a factor of 100–1000. Such rapid speciation events can also contribute to macro-evolution during mass extinction events, such as observed during the Cambrian explosion of biodiversity. A

  19. Tracking development paths: Monitoring driving forces and the impact of carbon-free energy sources in Spain

    International Nuclear Information System (INIS)

    O’ Mahony, Tadhg; Dufour, Javier

    2015-01-01

    Highlights: • The development path of Spain is analysed using an extended Kaya identity. • Effect of carbon free energy sources separated. • Nuclear energy acted to increase emissions as it declined in share. • Renewable energy penetration recently began to reduce carbon emissions. • Future policy must address wider factors of sustainable development. - Abstract: The evolution of the national development path has gravity in determining the future emissions outcomes of all nations. Deep reductions in emissions require a focus not just on energy and mitigation policy but on factors underlying this development. The Kaya identity has been recommended to track national progress with respect to sustainability and carbon emissions in the development path. This study applies an extended Kaya identity to the energy-related carbon emissions of Spain. Implemented through a divisia index decomposition annually from 1990 to 2011, it highlights the impact of factors such as affluence and energy intensity. A marked departure from previous studies is the separation of the effects of the carbon-free energy sources; both renewables and nuclear as fundamental mitigation measures. The results show that affluence and population have acted to increase emissions and energy intensity was increasing until recent years. Fuel substitution has acted to decrease emissions but while renewable energy has reduced emissions with the increasing importance of biomass, wind and solar, the decline in share of nuclear has acted to increase emissions. Implications for the development path and policy are discussed and lessons are relevant both for industrialised and industrialising nations

  20. Fine-tuning translation kinetics selection as the driving force of codon usage bias in the hepatitis A virus capsid.

    Science.gov (United States)

    Aragonès, Lluís; Guix, Susana; Ribes, Enric; Bosch, Albert; Pintó, Rosa M

    2010-03-05

    Hepatitis A virus (HAV), the prototype of genus Hepatovirus, has several unique biological characteristics that distinguish it from other members of the Picornaviridae family. Among these, the need for an intact eIF4G factor for the initiation of translation results in an inability to shut down host protein synthesis by a mechanism similar to that of other picornaviruses. Consequently, HAV must inefficiently compete for the cellular translational machinery and this may explain its poor growth in cell culture. In this context of virus/cell competition, HAV has strategically adopted a naturally highly deoptimized codon usage with respect to that of its cellular host. With the aim to optimize its codon usage the virus was adapted to propagate in cells with impaired protein synthesis, in order to make tRNA pools more available for the virus. A significant loss of fitness was the immediate response to the adaptation process that was, however, later on recovered and more associated to a re-deoptimization rather than to an optimization of the codon usage specifically in the capsid coding region. These results exclude translation selection and instead suggest fine-tuning translation kinetics selection as the underlying mechanism of the codon usage bias in this specific genome region. Additionally, the results provide clear evidence of the Red Queen dynamics of evolution since the virus has very much evolved to re-adapt its codon usage to the environmental cellular changing conditions in order to recover the original fitness.

  1. Fine-tuning translation kinetics selection as the driving force of codon usage bias in the hepatitis A virus capsid.

    Directory of Open Access Journals (Sweden)

    Lluís Aragonès

    2010-03-01

    Full Text Available Hepatitis A virus (HAV, the prototype of genus Hepatovirus, has several unique biological characteristics that distinguish it from other members of the Picornaviridae family. Among these, the need for an intact eIF4G factor for the initiation of translation results in an inability to shut down host protein synthesis by a mechanism similar to that of other picornaviruses. Consequently, HAV must inefficiently compete for the cellular translational machinery and this may explain its poor growth in cell culture. In this context of virus/cell competition, HAV has strategically adopted a naturally highly deoptimized codon usage with respect to that of its cellular host. With the aim to optimize its codon usage the virus was adapted to propagate in cells with impaired protein synthesis, in order to make tRNA pools more available for the virus. A significant loss of fitness was the immediate response to the adaptation process that was, however, later on recovered and more associated to a re-deoptimization rather than to an optimization of the codon usage specifically in the capsid coding region. These results exclude translation selection and instead suggest fine-tuning translation kinetics selection as the underlying mechanism of the codon usage bias in this specific genome region. Additionally, the results provide clear evidence of the Red Queen dynamics of evolution since the virus has very much evolved to re-adapt its codon usage to the environmental cellular changing conditions in order to recover the original fitness.

  2. From Coercion to Brute Force: Exploring the Evolution and Consequences of the Responsibility to Protect

    Science.gov (United States)

    2016-05-26

    Belgium-Bolivia-Brazil­ Canada-Chile-China- Colombia -Costa Rica-Cuba-Czechoslovakia-Denmark-Dominican Republic-Ecuador-Egypt-El Salvador-Ethiopia-France...request. They wanted no military forces on Libyan soil .112 While the UN and other nations considered this request, France took it one-step further, and...Charter of the United Nations with Argentina, Australia, Belarus, Belgium, Bolivia, Brazil, Canada, Chile, China, Colombia , Costa Rica, Cuba

  3. From Bosnia to Baghdad: The Evolution of US Army Special Forces From 1995-2004

    Science.gov (United States)

    2004-09-01

    BIJELJINA (OPERATION JOINT FORGE)............................... 13 H . FROM JCO TO SR (OPERATION ALLIED FORCE)......................... 14 I. SPECIAL...would only work with and report on Serbian villages and “Bosniak teams” exclusively focusing their efforts upon Bosnian Muslim villages.25 H . FROM JCO...processing station. Ramadani , the Sefer faction leader, arrived the next day at the demobilization point with approximately 40 faction members, including

  4. Crystal structure of a trapped catalytic intermediate suggests that forced atomic proximity drives the catalysis of mIPS.

    Science.gov (United States)

    Neelon, Kelly; Roberts, Mary F; Stec, Boguslaw

    2011-12-07

    1-L-myo-inositol-phosphate synthase (mIPS) catalyzes the first step of the unique, de novo pathway of inositol biosynthesis. However, details about the complex mIPS catalytic mechanism, which requires oxidation, enolization, intramolecular aldol cyclization, and reduction, are not fully known. To gain further insight into this mechanism, we determined the crystal structure of the wild-type mIPS from Archaeoglobus fulgidus at 1.7 Å, as well as the crystal structures of three active-site mutants. Additionally, we obtained the structure of mIPS with a trapped 5-keto-glucose-6-phosphate intermediate at 2 Å resolution by a novel (to our knowledge) process of activating the crystal at high temperature. A comparison of all of the crystal structures of mIPS described in this work suggests a novel type of catalytic mechanism that relies on the forced atomic proximity of functional groups. The lysine cluster is contained in a small volume in the active site, where random motions of these side chains are responsible for the progress of the complex multistep reaction as well as for the low rate of catalysis. The mechanism requires that functional groups of Lys-274, Lys-278, Lys-306, and Lys-367 assume differential roles in the protonation/deprotonation steps that must occur during the mIPS reaction. This mechanism is supported by the complete loss of activity of the enzyme caused by the Leu-257 mutation to Ala that releases the lysine containment. Copyright © 2011 Biophysical Society. Published by Elsevier Inc. All rights reserved.

  5. The sixth Euratom framework programme 2003-2006: a driving force for the construction of the Nuclear European Research Area

    International Nuclear Information System (INIS)

    Fernandez-Ruiz, P.; Forsstroem, H.; Goethem, G. van

    2005-01-01

    At the Lisbon 2000 summit, a strategic goal was proposed for the European Union: 'to become the most competitive knowledge-based economy with more and better employment and social cohesion by 2010'. Overall, in particular in the community of nuclear fission research, this EC initiative was well accepted by the main stakeholders. In Europe, the main stakeholders (i.e. suppliers and/or demanders) of nuclear research are actually: the research organisations (with mixed public/private funding), the manufacturing industry (or vendors), the utilities (or engineering companies), the regulatory bodies (or technical safety organisations) and the academia (or universities). In response to the Lisbon 2000 objectives, Commissioner P. BUSQUIN launched the concept of European Research Area (ERA) which sets also the frame for the FP-6. In this invited lecture, research and training in nuclear fission are looked at from a nuclear ERA perspective with emphasis on the three success factors of any European integration policy, namely: needs, vision and instruments, that ought to be strongly shared amongst the stakeholders in the EU-25. The following questions are addressed. What is driving the current EU trend towards more research, more education and more training in general? Regarding nuclear fission, in particular, who are the end-users of Euratom 'research and training' and what are their expectations (needs) from EU programmes? Do all stakeholders share the same vision about European research and training in nuclear fission? What are the instruments proposed by the Commission to the end-users to conduct joint research programmes? The above questions are all linked to nuclear knowledge management. It is shown that, in Community research, production of knowledge remains the most important objective, be it to generate products or services. However, dissemination/transfer (e.g. education and training) and exploitation (e.g. innovation) of knowledge become equally important as

  6. The evolution of vertical climbing in primates: evidence from reaction forces.

    Science.gov (United States)

    Hanna, Jandy B; Granatosky, Michael C; Rana, Pooja; Schmitt, Daniel

    2017-09-01

    Vertical climbing is an essential behavior for arboreal animals, yet limb mechanics during climbing are poorly understood and rarely compared with those observed during horizontal walking. Primates commonly engage in both arboreal walking and vertical climbing, and this makes them an ideal taxa in which to compare these locomotor forms. Additionally, primates exhibit unusual limb mechanics compared with most other quadrupeds, with weight distribution biased towards the hindlimbs, a pattern that is argued to have evolved in response to the challenges of arboreal walking. Here we test an alternative hypothesis that functional differentiation between the limbs evolved initially as a response to climbing. Eight primate species were recorded locomoting on instrumented vertical and horizontal simulated arboreal runways. Forces along the axis of, and normal to, the support were recorded. During walking, all primates displayed forelimbs that were net braking, and hindlimbs that were net propulsive. In contrast, both limbs served a propulsive role during climbing. In all species, except the lorisids, the hindlimbs produced greater propulsive forces than the forelimbs during climbing. During climbing, the hindlimbs tends to support compressive loads, while the forelimb forces tend to be primarily tensile. This functional disparity appears to be body-size dependent. The tensile loading of the forelimbs versus the compressive loading of the hindlimbs observed during climbing may have important evolutionary implications for primates, and it may be the case that hindlimb-biased weight support exhibited during quadrupedal walking in primates may be derived from their basal condition of climbing thin branches. © 2017. Published by The Company of Biologists Ltd.

  7. Sources Of Evolution Of The Japan Air Self Defense Force’s Strategy

    Science.gov (United States)

    2016-12-01

    national security. • Second is the battle space of war. “Defensive defense” strategy conducts war definitely in its territory and bears that most of its...russia-in- 2016/. 271Ankit Panda , “East China Sea: Japan Reacts as Chinese Air Force Conducts Miyako Strait Drill,” Diplomat, September 26, 2016...June 22, 2016. http://www.voanews.com/a/north-korea- failed-missile-tests-show-real-progress/3386692.html. Panda , Ankit. “East China Sea: Japan Reacts

  8. Mediterranean coastal dune vegetation: Are disturbance and stress the key selective forces that drive the psammophilous succession?

    Science.gov (United States)

    Ciccarelli, Daniela

    2015-11-01

    Plant communities of coastal dunes are distributed along a characteristic sea-inland gradient. Generally, there is a shift from annual and short height species with small leaves in the initial successional stages to perennial tall shrubs with tough leaves in later phases. Assessing the community-weighted mean (CWM) trait values is used in plant ecology to describe ecosystem properties especially during succession. In particular, CSR (Competitive, Stress-tolerant, and Ruderal strategy) classification allows us to explore community functional shifts in terms of disturbance, stress and competition selective forces. The functional basis of the psammophilous succession was studied based on the following questions: (1) Can we circumscribe different functional types among plant species of Mediterranean coastal dunes? (2) How do CWM trait values vary along the environmental sea-inland gradient? (3) What is the relative importance of competition, stress and disturbance in the processes of plant community assembling? (4) Can we postulate that along primary successions there is generally a shift from ruderality to stress-tolerance? An explorative analysis of functional groups was performed by Non-Metric Multidimensional Scaling (NMDS) analysing nine morpho-functional traits measured for 45 taxa from 880 dune plots localised in Tuscany (central Italy, Europe). NMDS ordination showed a scattered distribution of psammophytes that could not be delimited in precise plant functional types. The first NMDS axis has been interpreted as a leaf economics axis because it was correlated to leaf area (LA) and leaf dry matter content (LDMC), while the second one was a plant size axis because of its correlation with canopy height. Along the sea-inland gradient, pioneer plant communities of upper beach were dominated by ruderals (with the lowest values of LDMC and specific leaf area - SLA), well-adapted to the harsh environmental conditions of coastal dunes. More distant from the sea, where

  9. Positive Selection Drives the Evolution of rhino, a Member of the Heterochromatin Protein 1 Family in Drosophila.

    Directory of Open Access Journals (Sweden)

    2005-07-01

    Full Text Available Heterochromatin comprises a significant component of many eukaryotic genomes. In comparison to euchromatin, heterochromatin is gene poor, transposon rich, and late replicating. It serves many important biological roles, from gene silencing to accurate chromosome segregation, yet little is known about the evolutionary constraints that shape heterochromatin. A complementary approach to the traditional one of directly studying heterochromatic DNA sequence is to study the evolution of proteins that bind and define heterochromatin. One of the best markers for heterochromatin is the heterochromatin protein 1 (HP1, which is an essential, nonhistone chromosomal protein. Here we investigate the molecular evolution of five HP1 paralogs present in Drosophila melanogaster. Three of these paralogs have ubiquitous expression patterns in adult Drosophila tissues, whereas HP1D/rhino and HP1E are expressed predominantly in ovaries and testes respectively. The HP1 paralogs also have distinct localization preferences in Drosophila cells. Thus, Rhino localizes to the heterochromatic compartment in Drosophila tissue culture cells, but in a pattern distinct from HP1A and lysine-9 dimethylated H3. Using molecular evolution and population genetic analyses, we find that rhino has been subject to positive selection in all three domains of the protein: the N-terminal chromo domain, the C-terminal chromo-shadow domain, and the hinge region that connects these two modules. Maximum likelihood analysis of rhino sequences from 20 species of Drosophila reveals that a small number of residues of the chromo and shadow domains have been subject to repeated positive selection. The rapid and positive selection of rhino is highly unusual for a gene encoding a chromosomal protein and suggests that rhino is involved in a genetic conflict that affects the germline, belying the notion that heterochromatin is simply a passive recipient of "junk DNA" in eukaryotic genomes.

  10. Positive selection drives the evolution of rhino, a member of the heterochromatin protein 1 family in Drosophila.

    Directory of Open Access Journals (Sweden)

    Danielle Vermaak

    2005-07-01

    Full Text Available Heterochromatin comprises a significant component of many eukaryotic genomes. In comparison to euchromatin, heterochromatin is gene poor, transposon rich, and late replicating. It serves many important biological roles, from gene silencing to accurate chromosome segregation, yet little is known about the evolutionary constraints that shape heterochromatin. A complementary approach to the traditional one of directly studying heterochromatic DNA sequence is to study the evolution of proteins that bind and define heterochromatin. One of the best markers for heterochromatin is the heterochromatin protein 1 (HP1, which is an essential, nonhistone chromosomal protein. Here we investigate the molecular evolution of five HP1 paralogs present in Drosophila melanogaster. Three of these paralogs have ubiquitous expression patterns in adult Drosophila tissues, whereas HP1D/rhino and HP1E are expressed predominantly in ovaries and testes respectively. The HP1 paralogs also have distinct localization preferences in Drosophila cells. Thus, Rhino localizes to the heterochromatic compartment in Drosophila tissue culture cells, but in a pattern distinct from HP1A and lysine-9 dimethylated H3. Using molecular evolution and population genetic analyses, we find that rhino has been subject to positive selection in all three domains of the protein: the N-terminal chromo domain, the C-terminal chromo-shadow domain, and the hinge region that connects these two modules. Maximum likelihood analysis of rhino sequences from 20 species of Drosophila reveals that a small number of residues of the chromo and shadow domains have been subject to repeated positive selection. The rapid and positive selection of rhino is highly unusual for a gene encoding a chromosomal protein and suggests that rhino is involved in a genetic conflict that affects the germline, belying the notion that heterochromatin is simply a passive recipient of "junk DNA" in eukaryotic genomes.

  11. Complex tasks force hand laterality and technological behaviour in naturalistically housed chimpanzees: inferences in hominin evolution.

    Science.gov (United States)

    Mosquera, M; Geribàs, N; Bargalló, A; Llorente, M; Riba, D

    2012-01-01

    Clear hand laterality patterns in humans are widely accepted. However, humans only elicit a significant hand laterality pattern when performing complementary role differentiation (CRD) tasks. Meanwhile, hand laterality in chimpanzees is weaker and controversial. Here we have reevaluated our results on hand laterality in chimpanzees housed in naturalistic environments at Fundació Mona (Spain) and Chimfunshi Wild Orphanage (Zambia). Our results show that the difference between hand laterality in humans and chimpanzees is not as great as once thought. Furthermore, we found a link between hand laterality and task complexity and also an even more interesting connection: CRD tasks elicited not only the hand laterality but also the use of tools. This paper aims to turn attention to the importance of this threefold connection in human evolution: the link between CRD tasks, hand laterality, and tool use, which has important evolutionary implications that may explain the development of complex behaviour in early hominins.

  12. Distinct phases of eustatic and tectonic forcing for late Quaternary landscape evolution in southwest Crete, Greece

    Directory of Open Access Journals (Sweden)

    V. Mouslopoulou

    2017-09-01

    Full Text Available The extent to which climate, eustasy and tectonics interact to shape the late Quaternary landscape is poorly known. Alluvial fans often provide useful indexes that allow the decoding of information recorded on complex coastal landscapes, such as those of the eastern Mediterranean. In this paper we analyse and date (using infrared stimulated luminescence (IRSL dating a double alluvial fan system on southwest Crete, an island straddling the forearc of the Hellenic subduction margin, in order to constrain the timing and magnitude of its vertical deformation and discuss the factors contributing to its landscape evolution. The studied alluvial system is exceptional because each of its two juxtaposed fans records individual phases of alluvial and marine incision, thus providing unprecedented resolution in the formation and evolution of its landscape. Specifically, our analysis shows that the fan sequence at Domata developed during Marine Isotope Stage (MIS 3 due to five distinct stages of marine transgressions and regressions and associated river incision, in response to sea-level fluctuations and tectonic uplift at averaged rates of  ∼ 2.2 mm yr−1. Interestingly, comparison of our results with published tectonic uplift rates from western Crete shows that uplift during 20–50 kyr BP was minimal (or even negative. Thus, most of the uplift recorded at Domata must have occurred in the last 20 kyr. This implies that eustasy and tectonism impacted the landscape at Domata over mainly distinct time intervals (e.g. sequentially and not synchronously, with eustasy forming and tectonism preserving the coastal landforms.

  13. Was skin cancer a selective force for black pigmentation in early hominin evolution?

    Science.gov (United States)

    Greaves, Mel

    2014-01-01

    Melanin provides a crucial filter for solar UV radiation and its genetically determined variation influences both skin pigmentation and risk of cancer. Genetic evidence suggests that the acquisition of a highly stable melanocortin 1 receptor allele promoting black pigmentation arose around the time of savannah colonization by hominins at some 1–2 Ma. The adaptive significance of dark skin is generally believed to be protection from UV damage but the pathologies that might have had a deleterious impact on survival and/or reproductive fitness, though much debated, are uncertain. Here, I suggest that data on age-associated cancer incidence and lethality in albinos living at low latitudes in both Africa and Central America support the contention that skin cancer could have provided a potent selective force for the emergence of black skin in early hominins. PMID:24573849

  14. From Sequence and Forces to Structure, Function and Evolution of Intrinsically Disordered Proteins

    Science.gov (United States)

    Forman-Kay, Julie D.; Mittag, Tanja

    2015-01-01

    Intrinsically disordered proteins (IDPs), which lack persistent structure, are a challenge to structural biology due to the inapplicability of standard methods for characterization of folded proteins as well as their deviation from the dominant structure/function paradigm. Their widespread presence and involvement in biological function, however, has spurred the growing acceptance of the importance of IDPs and the development of new tools for studying their structure, dynamics and function. The interplay of folded and disordered domains or regions for function and the existence of a continuum of protein states with respect to conformational energetics, motional timescales and compactness is shaping a unified understanding of structure-dynamics-disorder/function relationships. On the 20th anniversary of this journal, Structure, we provide a historical perspective on the investigation of IDPs and summarize the sequence features and physical forces that underlie their unique structural, functional and evolutionary properties. PMID:24010708

  15. "Boom" and "Bust" cycles in virus growth suggest multiple selective forces in influenza a evolution

    Directory of Open Access Journals (Sweden)

    Marquart Mary E

    2011-04-01

    Full Text Available Abstract Background Influenza A virus evolution in humans is driven at least in part by mutations allowing the virus to escape antibody neutralization. Little is known about the evolution of influenza in birds, a major reservoir of influenza A. Methods Neutralizing polyclonal antiserum was raised in chicken against reassortant influenza virus, CalX, bearing the hemagglutinin (HA and neuraminidase (NA of A/California/7/2004 [H3N2]. CalX was serially passaged in the presence of anti-CalX polyclonal IgY to derive viruses capable of growth in the presence of antibody. Results Polyclonal chicken antibody neutralized both HA activity and infection by CalX, but had no effect on a strain bearing an earlier human H3 and an irrelevant neuraminidase (A/Memphis/71-Bellamy/42 [H3N1]. Surprisingly, most of the antibody-resistant viruses were still at least partially sensitive to neutralization of HA activity and viral infection. Although mutant HA genes bearing changes that might affect antibody neutralization were identified, the vast majority of HA sequences obtained were identical to wild type, and no individual mutant sequence was found in more than one passage, suggesting that those mutations that were observed did not confer sufficient selective advantage to come to dominate the population. Different passages yielded infectious foci of varying size and plaques of varying size and morphology. Yields of infectious virus and relative frequency of different morphologies changed markedly from passage to passage. Sequences of bulk, uncloned PCR products from antibody-resistant passages indicated changes in the PB2 and PA proteins with respect to the wild type virus. Conclusions Each antibody-selected passage consisted of a variety of different cocirculating populations, rather than pure populations of virus able to escape antibody by changes in antibody epitopes. The ability to escape antibody is apparently due to changes in genes encoding the viral

  16. Both Epistasis and Diversifying Selection Drive the Structural Evolution of the Ebola Virus Glycoprotein Mucin-Like Domain.

    Science.gov (United States)

    Ibeh, Neke; Nshogozabahizi, Jean Claude; Aris-Brosou, Stéphane

    2016-06-01

    Throughout the last 3 decades, Ebola virus (EBOV) outbreaks have been confined to isolated areas within Central Africa; however, the 2014 variant reached unprecedented transmission and mortality rates. While the outbreak was still under way, it was reported that the variant leading up to this outbreak evolved faster than previous EBOV variants, but evidence for diversifying selection was undetermined. Here, we test this selection hypothesis and show that while previous EBOV outbreaks were preceded by bursts of diversification, evidence for site-specific diversifying selection during the emergence of the 2014 EBOV clade is weak. However, we show strong evidence supporting an interplay between selection and correlated evolution (epistasis), particularly in the mucin-like domain (MLD) of the EBOV glycoprotein. By reconstructing ancestral structures of the MLD, we further propose a structural mechanism explaining how the substitutions that accumulated between 1918 and 1969 distorted the MLD, while more recent epistatic substitutions restored part of the structure, with the most recent substitution being adaptive. We suggest that it is this complex interplay between weak selection, epistasis, and structural constraints that has shaped the evolution of the 2014 EBOV variant. The role that selection plays in the emergence of viral epidemics remains debated, particularly in the context of the 2014 EBOV outbreak. Most critically, should such evidence exist, it is generally unclear how this relates to function and increased virulence. Here, we show that the viral lineage leading up to the 2014 outbreak underwent a complex interplay between selection and correlated evolution (epistasis) in a protein region that is critical for immune evasion. We then reconstructed the three-dimensional structure of this domain and showed that the initial mutations in this lineage deformed the structure, while subsequent mutations restored part of the structure. Along this mutational path, the

  17. The morphological development of newly inundated intertidal areas: the mechanisms driving the early evolution of an estuarine environment designed and constructed by humans

    Science.gov (United States)

    Dale, Jonathan; Burgess, Heidi; Cundy, Andrew

    2017-04-01

    Intertidal saltmarsh and mudflat habitats are of global importance due to the ecosystem, economic and cultural services they provide. These services include wildlife habitat provision and species diversity, immobilisation of pollutants and protection from coastal flooding. Saltmarsh and mudflat environments are, however, being lost and degraded due to erosion caused by rising sea levels and increased storminess. These losses are exacerbated by anthropogenic influences including land reclamation, increased coastal development and the construction of coastal flood defences which prevent the landwards migration of saltmarsh and mudflat environments, resulting in coastal squeeze. To compensate for saltmarsh and mudflat losses areas of the coastal hinterland are being inundated by breaching defences and constructing new defences inland, thus extending or constructing new estuarine environments; a processes known as de-embankment or managed realignment. Morphological engineering and landscaping within managed realignment sites prior to site inundation varies depending on the aims of the scheme. However, there is a shortage of data on the morphological evolution within these sites post site inundation impeding the ability of coastal engineers to effectively design and construct future sites. To date there has been a focus on the colonisation of marine macro fauna and flora within newly inundated managed realignment sites, which can be relatively rapid and easily quantified. Little is known of the morphological evolution in response to altered sedimentary processes, its driving mechanisms and therefore the success and ecological sustainability of these sites. This study evaluates the post-inundation morphological development of the largest open coast managed realignment site in Europe, at Medmerry on the south coast of the United Kingdom. Inundated in September 2013, the Medmerry Managed Realignment Site consists of a mosaic of former agricultural land and areas of lower

  18. Carbonaceous aerosols and pollutants over Delhi urban environment: Temporal evolution, source apportionment and radiative forcing

    Energy Technology Data Exchange (ETDEWEB)

    Bisht, D.S. [Indian Institute of Tropical Meteorology, New Delhi (India); Dumka, U.C., E-mail: dumka@aries.res.in [Aryabhatta Research Institute of Observational Sciences, Nainital (India); Kaskaoutis, D.G. [School of Natural Sciences, Shiv Nadar University, Tehsil Dadri (India); Pipal, A.S. [Department of Chemistry, Savitribai Phule Pune University, Pune (India); Srivastava, A.K. [Indian Institute of Tropical Meteorology, New Delhi (India); Soni, V.K.; Attri, S.D.; Sateesh, M. [India Meteorology Department, Lodhi Road, New Delhi (India); Tiwari, S. [Indian Institute of Tropical Meteorology, New Delhi (India)

    2015-07-15

    Particulate matter (PM{sub 2.5}) samples were collected over Delhi, India during January to December 2012 and analysed for carbonaceous aerosols and inorganic ions (SO{sub 4}{sup 2−} and NO{sub 3}{sup −}) in order to examine variations in atmospheric chemistry, combustion sources and influence of long-range transport. The PM{sub 2.5} samples are measured (offline) via medium volume air samplers and analysed gravimetrically for carbonaceous (organic carbon, OC; elemental carbon, EC) aerosols and inorganic ions (SO{sub 4}{sup 2−} and NO{sub 3}{sup −}). Furthermore, continuous (online) measurements of PM{sub 2.5} (via Beta-attenuation analyser), black carbon (BC) mass concentration (via Magee scientific Aethalometer) and carbon monoxide (via CO-analyser) are carried out. PM{sub 2.5} (online) range from 18.2 to 500.6 μg m{sup −3} (annual mean of 124.6 ± 87.9 μg m{sup −3}) exhibiting higher night-time (129.4 μg m{sup −3}) than daytime (103.8 μg m{sup −3}) concentrations. The online concentrations are 38% and 28% lower than the offline during night and day, respectively. In general, larger night-time concentrations are found for the BC, OC, NO{sub 3}{sup −}and SO{sub 4}{sup 2−}, which are seasonally dependent with larger differences during late post-monsoon and winter. The high correlation (R{sup 2} = 0.74) between OC and EC along with the OC/EC of 7.09 (day time) and 4.55 (night-time), suggest significant influence of biomass-burning emissions (burning of wood and agricultural waste) as well as secondary organic aerosol formation during daytime. Concentrated weighted trajectory (CWT) analysis reveals that the potential sources for the carbonaceous aerosols and pollutants are local emissions within the urban environment and transported smoke from agricultural burning in northwest India during post-monsoon. BC radiative forcing estimates result in very high atmospheric heating rates (~ 1.8–2.0 K day{sup −1}) due to agricultural burning effects

  19. Carbonaceous aerosols and pollutants over Delhi urban environment: Temporal evolution, source apportionment and radiative forcing

    International Nuclear Information System (INIS)

    Bisht, D.S.; Dumka, U.C.; Kaskaoutis, D.G.; Pipal, A.S.; Srivastava, A.K.; Soni, V.K.; Attri, S.D.; Sateesh, M.; Tiwari, S.

    2015-01-01

    Particulate matter (PM 2.5 ) samples were collected over Delhi, India during January to December 2012 and analysed for carbonaceous aerosols and inorganic ions (SO 4 2− and NO 3 − ) in order to examine variations in atmospheric chemistry, combustion sources and influence of long-range transport. The PM 2.5 samples are measured (offline) via medium volume air samplers and analysed gravimetrically for carbonaceous (organic carbon, OC; elemental carbon, EC) aerosols and inorganic ions (SO 4 2− and NO 3 − ). Furthermore, continuous (online) measurements of PM 2.5 (via Beta-attenuation analyser), black carbon (BC) mass concentration (via Magee scientific Aethalometer) and carbon monoxide (via CO-analyser) are carried out. PM 2.5 (online) range from 18.2 to 500.6 μg m −3 (annual mean of 124.6 ± 87.9 μg m −3 ) exhibiting higher night-time (129.4 μg m −3 ) than daytime (103.8 μg m −3 ) concentrations. The online concentrations are 38% and 28% lower than the offline during night and day, respectively. In general, larger night-time concentrations are found for the BC, OC, NO 3 − and SO 4 2− , which are seasonally dependent with larger differences during late post-monsoon and winter. The high correlation (R 2 = 0.74) between OC and EC along with the OC/EC of 7.09 (day time) and 4.55 (night-time), suggest significant influence of biomass-burning emissions (burning of wood and agricultural waste) as well as secondary organic aerosol formation during daytime. Concentrated weighted trajectory (CWT) analysis reveals that the potential sources for the carbonaceous aerosols and pollutants are local emissions within the urban environment and transported smoke from agricultural burning in northwest India during post-monsoon. BC radiative forcing estimates result in very high atmospheric heating rates (~ 1.8–2.0 K day −1 ) due to agricultural burning effects during the 2012 post-monsoon season. - Highlights: • Very high PM 2.5 (> 200 µg m −3 ) levels

  20. Forced current sheet structure, formation and evolution: application to magnetic reconnection in the magnetosphere

    Directory of Open Access Journals (Sweden)

    V. I. Domrin

    2004-07-01

    Full Text Available By means of a simulation model, the earlier predicted nonlinear kinetic structure, a Forced Kinetic Current Sheet (FKCS, with extremely anisotropic ion distributions, is shown to appear as a result of a fast nonlinear process of transition from a previously existing equilibrium. This occurs under triggering action of a weak MHD disturbance that is applied at the boundary of the simulation box. In the FKCS, current is carried by initially cold ions which are brought into the CS by convection from both sides, and accelerated inside the CS. The process then appears to be spontaneously self-sustained, as a MHD disturbance of a rarefaction wave type propagates over the background plasma outside the CS. Comparable to the Alfvénic discontinuity in MHD, transformation of electromagnetic energy into the energy of plasma flows occurs at the FKCS. But unlike the MHD case, ``free" energy is produced here: dissipation should occur later, through particle interaction with turbulent waves generated by unstable ion distribution being formed by the FKCS action. In this way, an effect of magnetic field ``annihilation" appears, required for fast magnetic reconnection. Application of the theory to observations at the magnetopause and in the magnetotail is considered.

  1. SU(6) symmetry and the quark forces

    International Nuclear Information System (INIS)

    Bartnik, E.A.; Namyslowski, J.M.

    1984-01-01

    The short distance forces between 3 valence quarks in the proton are investigated in perturbative QCD formulated on the light cone. These forces are the driving terms in the Brodsky-Lepage type evolution equation for the partially decomposed distribution amplitudes. The one-gluon exchange force, which is the lowest order force in the running coupling constant αsub(s) retains the SU(6) symmetry, while the αsub(s) 2 -order force, corresponding to one Coulomb gluon and one transverse gluon, breaks the SU(6) symmetry. The latter force contributes to the deviation from 1/2 of the d/u ratio for the proton, observed experimentally. In the kinematical domain of one fast quark, the αsub(s) 2 -order force gives the leading (1-x) 3 behaviour of the deep inelastic structure function F 2 (x), in contrast to the αsub(s)-order force, which gives (1-x) 5 , for xapprox.=1. (orig.)

  2. Nature of macroeconomic equilibrium and driving force of economic cycles in the light of difference between money and exergy forms in cost estimations

    Energy Technology Data Exchange (ETDEWEB)

    Bandura, A.V. [National Politechnical Univ., Kiev (Ukraine); Brodianskii, V.M. [Moscow Power Engineering Inst. Technical Univ. (Russian Federation)

    1996-11-01

    The main problem of exergy application directly in economic analysis is to find valid correlation between money-based cost and exergy based one (including exergy expenses of labour) and to define exergy cost as an economic category among the existing traditional economic ones. The present report is aimed to search the way for this macroeconomic problems` solution. It is demonstrated that exergy-based cost can be recalculated in a monetary form using a coefficient, defined as a ratio between money supply and the total exergy of all natural resources involved in production process, i.e. as a ratio between monetary and exergy bases. The difference between `natural` and current prices (P) can be used directly both for general quantitative characteristics of an economic cycles driving force and for control of market relationship imperfection. It is shown that for the period of time with the positive P, that is, current price is lower than a `natural` one, the recoveries in business cycles are observed. For the period of time with the negative P, that is, current price is higher than a natural one, economic recessions are observed. The moment of time when P = 0 corresponds to the turning point of a business cycle. In such a way the possibility to predict the turning points of business cycles is demonstrated. 14 refs, 2 figs, 2 tabs

  3. Molecular dynamics simulations shed light on the enthalpic and entropic driving forces that govern the sequence specific recognition between netropsin and DNA.

    Science.gov (United States)

    Dolenc, Jozica; Gerster, Sarah; van Gunsteren, Wilfred F

    2010-09-02

    With the aim to gain a better understanding of the various driving forces that govern sequence specific DNA minor groove binding, we performed a thermodynamic analysis of netropsin binding to an AT-containing and to a set of six mixed AT/GC-containing binding sequences in the DNA minor groove. The relative binding free energies obtained using molecular dynamics simulations and free energy calculations show significant variations with the binding sequence. While the introduction of a GC base pair in the middle or close to the middle of the binding site is unfavorable for netropsin binding, a GC base pair at the end of the binding site appears to have no negative influence on the binding. The results of the structural and energetic analyses of the netropsin-DNA complexes reveal that the differences in the calculated binding affinities cannot be explained solely in terms of netropsin-DNA hydrogen-bonding or interaction energies. In addition, solvation effects and entropic contributions to the relative binding free energy provide a more complete picture of the various factors determining binding. Analysis of the relative binding entropy indicates that its magnitude is highly sequence-dependent, with the ratio |TDeltaDeltaS|/|DeltaDeltaH| ranging from 0.07 for the AAAGA to 1.7 for the AAGAG binding sequence, respectively.

  4. Daylighting as the Driving Force of the Design Process: from the Results of a Survey to the Implementation into an Advanced Daylighting Project

    Directory of Open Access Journals (Sweden)

    Valerio R.M. Lo Verso

    2014-12-01

    Full Text Available This paper presents a study for the transformation of an industrial area in Turin, Italy. The area hosts two buildings (one of which appointed as listed to be transformed into dwellings. A synergic approach was adopted which combined expertise from architecture, social-economics, psychology and building physics sciences. Building physics sciences lead the research team. A user-centered design was pursued, using a bottom-up approach. A specifically developed questionnaire was submitted on-line to potential users. The survey showed that ‘amount of daylight’, ‘size of rooms’, ‘tranquility of the area’ and ‘presence of a private garden’ were perceived by users to be the most positive aspects of both their present and future, ideal home. These results were then implemented into the project. The exploitation of daylight became the driving force of the transformation project. Especially for the listed building, skylights and light wells were designed to bring daylight into the cores of the buildings, which host common spaces such as libraries or study rooms. The amount of daylight was assessed through the legislative index of the average daylight factor and through a climate-based modeling approach, calculating dynamic metrics such as the spatial daylight autonomy and the Useful Daylight Illuminance. The paper critically compares and discusses these two approaches. Finally, the energy demand for lighting was also calculated to analyze how the increased exploitation of daylight may imply a reduced need for electricity for lighting.

  5. Very high geothermal gradient in near surface of the Whataroa Valley adjacent to the Alpine Fault: topographic driving forces and permeable mountains

    Science.gov (United States)

    Upton, P.; Sutherland, R.; Townend, J.; Coussens, J.; Capova, L.

    2015-12-01

    The first phase of the Deep Fault Drilling Project (DFDP-1B) yielded a geothermal gradient of 62.6 ± 2.1 °C/km from a depth of 126 m where it intersected the Alpine Fault principal slip surface beneath Gaunt Creek (Sutherland et al. 2012). Ambient fluid pressures in DFDP-2B at Whataroa River were 8-10% above hydrostatic and a geothermal gradient of >130°C/km was determined, the geothermal gradient being considerably higher than we had predicted previously. 3D coupled thermal/fluid flow models have been generated of the Whataroa Valley and the DFDP-2 drill site. Modelling confirms that the following features, present in the Whataroa Valley, are a requirement for a geothermal gradient of >130°C/km at a depth of 1km beneath the valley; high topography, permeability on the order of 10-15 m2 in both the mountains and beneath the valleys to depths of > 1km below the valley floor, and abundant fluid. The high permeability and large topographic driving force leads to abundant meteoric water flowing downward through the mountains, hitting the permeability barrier of the Alpine Fault and being pushed upward into the valleys. The high geothermal gradient of the DFDP-2B borehole implies that the valleys also have a very high permeability which is likely a result of rock damage along the Alpine Fault.

  6. The Driving Forces of Guest Substitution in Gas Hydrates—A Laser Raman Study on CH4-CO2 Exchange in the Presence of Impurities

    Directory of Open Access Journals (Sweden)

    Bettina Beeskow-Strauch

    2012-02-01

    Full Text Available The recovery of CH4 gas from natural hydrate formations by injection of industrially emitted CO2 is considered to be a promising solution to simultaneously access an unconventional fossil fuel reserve and counteract atmospheric CO2 increase. CO2 obtained from industrial processes may contain traces of impurities such as SO2 or NOx and natural gas hydrates may contain higher hydrocarbons such as C2H6 and C3H8. These additions have an influence on the properties of the resulting hydrate phase and the conversion process of CH4-rich hydrates to CO2-rich hydrates. Here we show results of a microscopic and laser Raman in situ study investigating the effects of SO2-polluted CO2 and mixed CH4-C2H6 hydrate on the exchange process. Our study shows that the key driving force of the exchange processes is the establishment of the chemical equilibrium between hydrate phase and the surrounding phases. The exchange rate is also influenced by the guest-to-cavity ratio as well as the thermodynamic stability in terms of p-T conditions of the original and resulting hydrate phase. The most effective molecule exchange is related to structural changes (sI-sII which indicates that hydrate decomposition and reformation processes are the occurring processes.

  7. Does retained-seed priming drive the evolution of serotiny in drylands? An assessment using the cactus Mammillaria hernandezii.

    Science.gov (United States)

    Santini, Bianca A; Martorell, Carlos

    2013-02-01

    Serotinous plants retain their seeds for a long time. In deserts, retained seeds undergo hydration-dehydration cycles and thus may become primed. Priming enhances germination and seedling vigor. We test the hypothesis that serotiny evolves because it provides a site protected from predators in which seeds can become primed. Rainfall-cued dispersal of primed seeds may enhance this effect. We tested this hypothesis with Mammillaria hernandezii through protein-content analyses; field and laboratory germination experiments with primed, unprimed, and retained seeds; and fitness estimations from demographic models. Hydration-dehydration cycles induced priming, enhancing germination. Artificial priming and retention in the parent plant for 1 yr induced similar changes in seed protein patterns, suggesting that priming occurs naturally while seeds are retained. Under field conditions, germination of seeds retained for 1 yr more than doubled that of seeds of the same cohort that were not primed or that remained buried for 1 yr. The first seeds to germinate died rapidly. Serotinous plants whose seeds underwent priming had higher fitness than those whose seeds were in the soil seed bank or that did not experience priming. Priming in soil seed banks may be costly because of high predation, so seed protection during priming is sufficient to promote the evolution of serotiny. Bet hedging contributes to this process. Rapid germination of primed seeds that respond to brief rainfall events is disadvantageous because such rainfall is insufficient for seedling survival. Serotinous species counteract this cost by cueing dispersal with heavy precipitation.

  8. Orbital evolution of a test particle around a black hole: indirect determination of the self-force in the post-Newtonian approximation

    International Nuclear Information System (INIS)

    Burko, Lior M

    2006-01-01

    Comparing the corrections to Kepler's law with orbital evolution under a self-force, we extract the finite, already regularized part of the latter in a specific gauge. We apply this method to a quasi-circular orbit around a Schwarzschild black hole of an extreme mass ratio binary, and determine the first- and second-order conservative gravitational self-force in a post-Newtonian expansion. We use these results in the construction of the gravitational waveform, and revisit the question of the relative contribution of the self-force and spin-orbit coupling

  9. North America as driving force

    Energy Technology Data Exchange (ETDEWEB)

    Grunwald, Markus

    2012-07-01

    The fact that Europe is comparably small in size and densely populated puts limits to the use of PV solar trackers. But that's no reason for the tracker manufacturers to throw in the towel. Those prepared to take a look abroad may yet feel their hearts beat faster.

  10. Driving forces of researchers mobility

    Science.gov (United States)

    Gargiulo, Floriana; Carletti, Timoteo

    2014-05-01

    Starting from the dataset of the publication corpus of the APS during the period 1955-2009, we reconstruct the individual researchers trajectories, namely the list of the consecutive affiliations for each scholar. Crossing this information with different geographic datasets we embed these trajectories in a spatial framework. Using methods from network theory and complex systems analysis we characterise these patterns in terms of topological network properties and we analyse the dependence of an academic path across different dimensions: the distance between two subsequent positions, the relative importance of the institutions (in terms of number of publications) and some socio-cultural traits. We show that distance is not always a good predictor for the next affiliation while other factors like ``the previous steps'' of the career of the researchers (in particular the first position) or the linguistic and historical similarity between two countries can have an important impact. Finally we show that the dataset exhibit a memory effect, hence the fate of a career strongly depends from the first two affiliations.

  11. The driving force behind all

    International Nuclear Information System (INIS)

    Zischka, A.

    1988-01-01

    The book reviews the history of energy uses in the world, arranging the material into three main sections corresponding to the three historical revolutions in the development of man's capacity to use the energy available in the world for his own purposes. These three mile posts are the mastering and utilization of fire, the Neolithic revolution, and the industrial revolution. The author tells the story excitingly and in a fascinating way explaining the very first steps and the long way mankind took, to achieve the technological systems we have now. Concentrating on the developments and interactions of significance to today's situation, the author presents data and information that brings life into history and fosters independent thinking. Right answers need the right questions, so the author tries to find out what has become indispensable for us, since when we have it, and who found it, and why, and what the consequences are for the present generation. The author mentions the persons, their biographies, and their achievements, showing that all knowledge and success was achieved by hard work. (orig./DG) [de

  12. Revealing the Driving Forces of Mid-Cities Urban Growth Patterns Using Spatial Modeling: a Case Study of Los Ángeles, Chile

    Directory of Open Access Journals (Sweden)

    Mauricio I. Aguayo

    2007-06-01

    Full Text Available City growth and changes in land-use patterns cause various important social and environmental impacts. To understand the spatial and temporal dynamics of these processes, the factors that drive urban development must be identified and analyzed, especially those factors that can be used to predict future changes and their potential environmental effects. Our objectives were to quantify the relationship between urban growth and its driving forces and to predict the spatial growth pattern based on historical land-use changes for the city of Los Ángeles in central Chile. This involved the analysis of images from 1978, 1992, and 1998 and characterization of the spatial pattern of land-use change; the construction of digital coverage in GIS; the selection of predictive variables through univariate analysis; the construction of logistic regression models using growth vs. nongrowth for 1978-1992 as the dependent variable; and the prediction of the probability of land-use change by applying the regression model to the 1992-1998 period. To investigate the influence of spatial scale, we constructed several sets of models that contained (1 only distance variables, e.g., distance to highways; (2 only scale-dependent density variables, e.g., density of urban area within a 600-m radius; (3 both distance and density variables; and (4 both distance and density variables at several spatial scales. The environmental variables were included in all models. The combination of distance and density variables at several scales is required to appropriately capture the multiscale urban growth process. The best models correctly predict ~90% of the observed land-use changes for 1992-1998. The distance to access roads, densities of the urban road system and urbanized area at various scales, and soil type were the strongest predictors of the growth pattern. Other variables were less important or not significant in explaining the urban growth process. Our approach, which

  13. Assessing driving forces of land use and land cover change by a mixed-method approach in north-eastern Ghana, West Africa.

    Science.gov (United States)

    Kleemann, Janina; Baysal, Gülendam; Bulley, Henry N N; Fürst, Christine

    2017-07-01

    Land use and land cover change (LULCC) is the result of complex human-environmental interactions. The high interdependencies in social-ecological systems make it difficult to identify the main drivers. However, knowledge of key drivers of LULCC, including indirect (underlying) drivers which cannot be easily determined by spatial or economic analyses, is essential for land use planning and especially important in developing countries. We used a mixed-method approach in order to detect drivers of LULCC in the Upper East Region of northern Ghana by different qualitative and quantitative methods which were compared in a confidence level analysis. Viewpoints from experts help to answer why the land use is changing, since many triggering effects, especially non-spatial and indirect drivers of LULCC, are not measurable by other methodological approaches. Geo-statistical or economic analyses add to validate the relevance of the expert-based results. First, we conducted in-depth interviews and developed a list of 34 direct and indirect drivers of LULCC. Subsequently, a group of experts was asked in a questionnaire to select the most important drivers by using a Likert scale. This information was complemented by remote sensing analysis. Finally, the driver analysis was compared to information from literature. Based on these analyses there is a very high confidence that population growth, especially in rural areas, is a major driver of LULCC. Further, current farming practice, bush fires, livestock, the road network and climate variability were the main direct drivers while the financial capital of farmers and customary norms regarding land tenure were listed as important indirect drivers with high confidence. Many of these driving forces, such as labour shortage and migration, are furthermore interdependent. Governmental laws, credits, the service by extension officers, conservational agriculture and foreign agricultural medium-scale investments are currently not driving

  14. Role of the DNA Mismatch Repair Gene MutS4 in Driving the Evolution of Mycobacterium yongonense Type I via Homologous Recombination.

    Science.gov (United States)

    Kim, Byoung-Jun; Kim, Bo-Ram; Kook, Yoon-Hoh; Kim, Bum-Joon

    2017-01-01

    We recently showed that Mycobacterium yongonense could be divided into two genotypes: Type I, in which the rpoB gene has been transferred from Mycobacterium parascrofulaceum , and Type II, in which the rpoB gene has not been transferred. Comparative genome analysis of three M. yongonense Type I, two M. yongonense Type II and M. parascrofulaceum type strains were performed in this study to gain insight into gene transfer from M. parascrofulaceum into M. yongonense Type I strains. We found two genome regions transferred from M. parascrofulaceum : one contained 3 consecutive genes, including the rpoBC operon, and the other contained 57 consecutive genes that had been transferred into M. yongonense Type I genomes via homologous recombination. Further comparison between the M. yongonense Type I and II genomes revealed that Type I, but not Type II has a distinct DNA mismatch repair gene ( MutS4 subfamily) that was possibly transferred via non-homologous recombination from other actinomycetes. We hypothesized that it could facilitate homologous recombination from the M. parascrofulaceum to the M. yongonense Type I genomes. We therefore generated recombinant Mycobacterium smegmatis containing a MutS4 operon of M. yongonense . We found that the M. tuberculosis rpoB fragment with a rifampin resistance-conferring mutation was more frequently inserted into recombinant M. smegmatis than the wild type, suggesting that MutS4 is a driving force in the gene transfer from M. parascrofulaceum to M. yongonense Type I strains via homologous recombination. In conclusion, our data indicated that MutS4 in M. yongonense Type I genomes may drive gene transfer from M. parascrofulaceum via homologous recombination, resulting in division of M. yongonense into two genotypes, Type I and II.

  15. Role of the DNA Mismatch Repair Gene MutS4 in Driving the Evolution of Mycobacterium yongonense Type I via Homologous Recombination

    Directory of Open Access Journals (Sweden)

    Byoung-Jun Kim

    2017-12-01

    Full Text Available We recently showed that Mycobacterium yongonense could be divided into two genotypes: Type I, in which the rpoB gene has been transferred from Mycobacterium parascrofulaceum, and Type II, in which the rpoB gene has not been transferred. Comparative genome analysis of three M. yongonense Type I, two M. yongonense Type II and M. parascrofulaceum type strains were performed in this study to gain insight into gene transfer from M. parascrofulaceum into M. yongonense Type I strains. We found two genome regions transferred from M. parascrofulaceum: one contained 3 consecutive genes, including the rpoBC operon, and the other contained 57 consecutive genes that had been transferred into M. yongonense Type I genomes via homologous recombination. Further comparison between the M. yongonense Type I and II genomes revealed that Type I, but not Type II has a distinct DNA mismatch repair gene (MutS4 subfamily that was possibly transferred via non-homologous recombination from other actinomycetes. We hypothesized that it could facilitate homologous recombination from the M. parascrofulaceum to the M. yongonense Type I genomes. We therefore generated recombinant Mycobacterium smegmatis containing a MutS4 operon of M. yongonense. We found that the M. tuberculosis rpoB fragment with a rifampin resistance-conferring mutation was more frequently inserted into recombinant M. smegmatis than the wild type, suggesting that MutS4 is a driving force in the gene transfer from M. parascrofulaceum to M. yongonense Type I strains via homologous recombination. In conclusion, our data indicated that MutS4 in M. yongonense Type I genomes may drive gene transfer from M. parascrofulaceum via homologous recombination, resulting in division of M. yongonense into two genotypes, Type I and II.

  16. Pump depletion limited evolution of the relativistic plasma wave-front in a forced laser-wakefield accelerator

    International Nuclear Information System (INIS)

    Fang, F; Clayton, C E; Marsh, K A; Pak, A E; Ralph, J E; Joshi, C; Lopes, N C

    2009-01-01

    In a forced laser-wakefield accelerator experiment (Malka et al 2002 Science 298 1596) where the length of the pump laser pulse is a few plasma periods long, the leading edge of the laser pulse undergoes frequency downshifting and head erosion as the laser energy is transferred to the wake. Therefore, after some propagation distance, the group velocity of the leading edge of the pump pulse-and thus of the driven electron plasma wave-will slow down. This can have implications for the dephasing length of the accelerated electrons and therefore needs to be understood experimentally. We have carried out an experimental investigation where we have measured the velocity v f of the 'wave-front' of the plasma wave driven by a nominally 50 fs (full width half maximum), intense (a 0 ≅ 1), 0.815 μm laser pulse. To determine the speed of the wave front, time- and space-resolved refractometry, interferometry and Thomson scattering were used. Although a laser pulse propagating through a relatively low-density plasma (n e = 1.3 x 10 19 cm -3 ) showed no measurable changes in v f over 1.3 mm (and no accelerated electrons), a high-density plasma (n e = 5 x 10 19 cm -3 ) generated accelerated electrons and showed a continuous change in v f as the laser pulse propagated through the plasma. Possible causes and consequences of the observed v f evolution are discussed.

  17. Drive Stands

    Data.gov (United States)

    Federal Laboratory Consortium — The Electrical Systems Laboratory (ESL)houses numerous electrically driven drive stands. A drive stand consists of an electric motor driving a gearbox and a mounting...

  18. Pump depletion limited evolution of the relativistic plasma wave-front in a forced laser-wakefield accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Fang, F; Clayton, C E; Marsh, K A; Pak, A E; Ralph, J E; Joshi, C [Department of Electrical Engineering, University of California, Los Angeles, CA 90095 (United States); Lopes, N C [Grupo de Lasers e Plasmas, Instituto Superior Tecnico, Lisbon (Portugal)], E-mail: cclayton@ucla.edu

    2009-02-15

    In a forced laser-wakefield accelerator experiment (Malka et al 2002 Science 298 1596) where the length of the pump laser pulse is a few plasma periods long, the leading edge of the laser pulse undergoes frequency downshifting and head erosion as the laser energy is transferred to the wake. Therefore, after some propagation distance, the group velocity of the leading edge of the pump pulse-and thus of the driven electron plasma wave-will slow down. This can have implications for the dephasing length of the accelerated electrons and therefore needs to be understood experimentally. We have carried out an experimental investigation where we have measured the velocity v{sub f} of the 'wave-front' of the plasma wave driven by a nominally 50 fs (full width half maximum), intense (a{sub 0} {approx_equal} 1), 0.815 {mu}m laser pulse. To determine the speed of the wave front, time- and space-resolved refractometry, interferometry and Thomson scattering were used. Although a laser pulse propagating through a relatively low-density plasma (n{sub e} = 1.3 x 10{sup 19} cm{sup -3}) showed no measurable changes in v{sub f} over 1.3 mm (and no accelerated electrons), a high-density plasma (n{sub e} = 5 x 10{sup 19} cm{sup -3}) generated accelerated electrons and showed a continuous change in v{sub f} as the laser pulse propagated through the plasma. Possible causes and consequences of the observed v{sub f} evolution are discussed.

  19. Estímulos ao Desenvolvimento Tecnológico: Influência do Mercado Driving Forces for Technology Development: Market

    Directory of Open Access Journals (Sweden)

    José de A. Cid

    2002-01-01

    Full Text Available Hoje em dia não se discute mais a importância da Pesquisa e Desenvolvimento para a sobrevivência e longevidade de uma Empresa. Todo tipo de indústria sente o impacto do aumento da competição e da velocidade dos avanços tecnológicos. Entretanto, os recursos estão escassos, tanto para as despesas necessárias às atividades de negócio quanto para a pesquisa, o que deixa os gerentes com a difícil tarefa de decidir onde os recursos serão aplicados. Anos atrás, quando os recursos eram (aparentemente ilimitados a força que impulsionava a pesquisa era o desafio da descoberta do novo. A complexidade do processo, os intricados métodos de análise, a quebra de barreiras do conhecimento, alimentavam as mentes dos cientistas. Depois da pesquisa, os profissionais de marketing deveriam encontrar mercados para os novos produtos. Atualmente a pesquisa de mercado, as ferramentas de análise de negócio e outros aspectos outrora desconhecidos dos cientistas dominam as mesas dos gerentes. Este artigo descreve três diferentes abordagens na distribuição de recursos para pesquisa e resume alguns dos princípios que ajudam as empresas a funcionar melhor.Nowadays the importance of Research and Development to a Company survival and longevity is well known. Virtually every industry feels the impact of increased competition and the fast pace of technology change. However, resources are getting scarce, both for doing business and research as well, leaving managers with the tough job of selecting which project will get funding. Years ago, when money was (seemingly unlimited the driving force to research was the challenge of inventing something new. The process complexity, the intricate analysis methods, the breaking of new frontiers were the food for the scientists inquiring minds. Then marketing professionals had to work to find or create market. Now market research, business analysis tools and other aspects once unknown to scientists rule. This article

  20. Study on HCl Driving Force for the Reaction of NaCl-Maleic Acid Mixing Single Droplet Using Micro-FTIR Spectroscopy

    Science.gov (United States)

    He, Xiang; Zhang, Yunhong

    2016-04-01

    Chemical aging is the one of the most important physicochemical process in atmospheric aerosols. Mixing of sea salt and water-soluble organic components has profound effects on the volatile characteristic and evolving chemical composition of the anthropogenic origin aerosols, which are poorly understood. In this study, the chemical reaction behavior of the mixture of NaCl and maleic acid (H2MA) micron-level single droplet was investigated using a gas-flow system combined with microscopic Fourier transform infrared (micro-FTIR) spectrometer over the range of relative humidity (63˜95% RH) for the first time. The results showed that the mixture of NaCl and H2MA single droplet could react to form monosodium maleate salt (NaHMA) at the constant RH from the characterization of the FTIR. The reaction is a result of an acid displacement reaction R1, which is driven by high volatility of the HCl product. NaCl(aq)+H2MA(aq)=NaHMA(aq)+HCl(aq,g) (R1) According to the change tendency of the absorbance values of 1579 cm-1 COO- stretching band of the NaHMA dependent upon reaction times at different RHs, the growth range of the trend which could lead to the faster reaction rate was obvious at lower RH. The water content of the droplet was also more likely to reduce rapidly with the loss of the RH from the absorbance changes of 3400 cm-1H2O stretching band dependent upon reaction times. These may be due to irreversible evaporation of HCl gas which is the main driving force for this type of reaction and the NaHMA is a less hygroscopic component compared to H2MA. And the HCl gas is more likely to evaporate faster from the single droplet and promote the reaction rate and the consumption of water content at lower RH. These results could help in understanding the chemical conversion processes of water-soluble dicarboxylic acids to dicarboxylate salts, as well as the consumption of Cl in sea salt aerosols by organic acids in the atmosphere.

  1. Dementia & Driving

    Science.gov (United States)

    ... have to give up driving. Many people associate driving with self-reliance and freedom; the loss of driving privileges ... familiar roads and avoid long distances. Avoid heavy traffic and heavily traveled roads. Avoid driving at night and in bad weather. Reduce the ...

  2. Preliminary measurement of the drag force on a porous cylinder with fluid evolution under conditions relevant to pulverised-fuel combustion

    Energy Technology Data Exchange (ETDEWEB)

    Dijan Supramono; Graham J. Nathan; Peter J. Ashman; Peter J. Mullinger [University of Adelaide, Adelaide, SA (Australia). Cooperative Research Centre for Clean Power from Lignite, Schools of Chemical Engineering and Mechanical Engineering

    2003-07-01

    The trajectories of the particles in pulverised coal combustion systems determine their residence times and reaction environments, and hence coal burnout and flame length. The trajectories, in turn, depend upon the drag coefficient of the particle. The effect of the evolution of fluid from the surface of the particle on this coefficient has never been measured before, particularly at the low particle Reynolds numbers that apply during coal combustion. Therefore mathematical models must rely on assumed sphere drag coefficients, which do not account for the effect of fluid evolving from the surface. A technique of using a porous cylinder mounted on a pendulum, instead of a sphere, through which fluid can be forced to evolve, simulating fluid evolution in coal devolatilisation and char burning, is used. The pendulum is capable of measuring drag forces of the order of 10-5 to 10-6 Newton, at Reynolds numbers similar to that experienced by coal particles. This paper presents preliminary measurements of drag force at relevant conditions. The working fluid is water in the first instance, although it will be extended to diluted glycerine in the future. The cross flow is provided by a water tunnel and the ejected fluid is induced by a separate pump. Both the Reynolds number and the ratio of evolution velocity to free-stream velocity are chosen to span conditions relevant to pulverised coal combustion. 16 refs., 5 figs., 2 tabs.

  3. Distracted driving

    Science.gov (United States)

    ... including maps) The Dangers of Talking on the Phone While Driving You are four times more likely to get ... of reach. If you are caught using a phone while driving, you may risk a ticket or fine. Most ...

  4. Distracted Driving

    Science.gov (United States)

    ... and increased awareness of distracted driving using radio advertisements, news stories, and similar media. After the projects ... available at www.trafficsafetymarketing.gov . Distracted Driving Enforcement – TV Ads (Paid). For re-tagging, go to: www. ...

  5. Tensor force effect on the evolution of single-particle energies in some isotopic chains in the relativistic Hartree-Fock approximation

    Science.gov (United States)

    López-Quelle, M.; Marcos, S.; Niembro, R.; Savushkin, L. N.

    2018-03-01

    Within a nonlinear relativistic Hartree-Fock approximation combined with the BCS method, we study the effect of the nucleon-nucleon tensor force of the π-exchange potential on the spin- and pseudospin-orbit doublets along the Ca and Sn isotopic chains. We show how the self-consistent tensor force effect modifies the splitting of both kinds of doublets in an interdependent form, leading, quite generally, to opposite effects in the accomplishment of the spin and pseudospin symmetries (the one is restored, the other one deteriorates and vice versa). The ordering of the single-particle energy levels is crucial to this respect. Also, we observe a mutual dependence on the evolution of the shell closure gap Z = 50 and the energy band outside the core, along the Sn chain, as due to the tensor force. In fact, when the shell gap is quenched the outside energy band is enlarged, and vice versa. A reduction of the strength of the pion tensor force with respect to its experimental value from the nucleon-nucleon scattering is needed to get results closer to the experiment. Pairing correlations act to some extent in the opposite direction of the tensor term of the one-pion-exchange force.

  6. [Innovation drive is the original motive force of discipline construction: the developing road of Department of Burns and Plastic Surgery in the 309th Hospital of PLA].

    Science.gov (United States)

    Jia, C Y

    2018-03-20

    Discipline construction is a systematic project, covering clinic, teaching, scientific research, management, and humanity. Based on the perspective of innovation drive, from the aspects of discipline structure setting, specialized laboratory construction, sub-specialty formation, clinical characteristic and advantage formation, and management concept update, this article summarizes the growth process of Department of Burns and Plastic Surgery in the 309th Hospital of PLA.

  7. [Driving forces of carbon emission from energy consumption in China old industrial cities: a case study of Shenyang City, Northeast China].

    Science.gov (United States)

    Ren, Wan-Xia; Geng, Yong; Xue, Bing

    2012-10-01

    To quantitatively analyze the effects of anthropogenic factors on regional environmental quality is a hot topic in the field of sustainable development research. Taking the typical old industrial city Shenyang in Northeast China as a case, and by using the IPCC method for calculating carbon emission from energy consumption, this paper estimated the carbon emission from energy consumption in the city in 1978-2009, and a time series analysis on the anthropogenic factors driving this carbon emission was made by the STIRPAT model based upon Kaya equation and ridge regression. In 1978-2009, the carbon emission in the city had a slow increase first, slow decrease then, and a rapid increase thereafter. The total carbon emission in 2009 was 4.6 times of that in 1978. Population growth was the main factor driving the growth of the emission, and there existed an equal-proportional variation between the population growth and the carbon emission growth. Urbanization was another main driving factor followed by population growth, and the per capita GDP was positively correlated with the carbon emission. Kuznets curve did not exist for the relationship between economic development and carbon emission in Shenyang. Energy source intensity reduction (representing technology improvement) was the main factor driving the reduction of the total carbon emission.

  8. Voluntary drive-dependent changes in vastus lateralis motor unit firing rates during a sustained isometric contraction at 50% of maximum knee extension force.

    NARCIS (Netherlands)

    de Ruiter, C.J.; Elzinga, M.J.; Verdijk, PW; van Mechelen, W.; de Haan, A.

    2004-01-01

    The purpose of the present study was to relate the expected inter-subject variability in voluntary drive of the knee extensor muscles during a sustained isometric contraction to the changes in firing rates of single motor units. Voluntary activation, as established with super-imposed electrical

  9. Electric drives

    CERN Document Server

    Boldea, Ion

    2005-01-01

    ENERGY CONVERSION IN ELECTRIC DRIVESElectric Drives: A DefinitionApplication Range of Electric DrivesEnergy Savings Pay Off RapidlyGlobal Energy Savings Through PEC DrivesMotor/Mechanical Load MatchMotion/Time Profile MatchLoad Dynamics and StabilityMultiquadrant OperationPerformance IndexesProblemsELECTRIC MOTORS FOR DRIVESElectric Drives: A Typical ConfigurationElectric Motors for DrivesDC Brush MotorsConventional AC MotorsPower Electronic Converter Dependent MotorsEnergy Conversion in Electric Motors/GeneratorsPOWER ELECTRONIC CONVERTERS (PECs) FOR DRIVESPower Electronic Switches (PESs)The

  10. Characterizing Spatiotemporal Pattern of Land Use Change and Its Driving Force Based on GIS and Landscape Analysis Techniques in Tianjin during 2000–2015

    Directory of Open Access Journals (Sweden)

    Yafei Li

    2017-05-01

    Full Text Available The spatial and temporal characteristics and driving factors analysis of regional land use are the core scientific problems in the research of ecological environment and human sustainable development. It is also an important basis for the government to formulate land management policy. Based on the land use maps of 2000, 2005, 2010 and 2015, this article analyzed the spatiotemporal pattern of land use change in Tianjin, and determined the relative importance of each driving factor of land use change. The main features of land use change were the continuous expansion of built-up land (1386.89 km2/74.73% gains and the decrease of arable land area (1181.60 km2/16.84% losses. The area and intensity of land use change were not completely consistent, such as Wuqing and Jixian. The hotspots of land use change mainly were located in the main urban region in Tianjin, around the suburban settlements and Binhai New Area. The landscape pattern in the research region has also changed significantly. The Largest patch index (LPI and largest shape index (LSI of arable land showed an increasing trend, and the degree of landscape fragmentation of arable land was deepened. The trend of landscape index of built-up land was similar to that of arable land, but the change intensity was more severe. In addition, the article also used the stepwise regression analysis in the multiple regression to analyze the relative importance of various driving factors, indicating that the driving factors of the built-up land and arable land change were obviously different in different periods. Government policies also have a significant impact on land use change, such as establishing the Tianjin Binhai New Area (TBNA.

  11. Evolution operators and transformation of states under uniform and an/or elastic forces into free particle states

    International Nuclear Information System (INIS)

    Dattoli, G.; Torre, A.

    1999-01-01

    In this paper are exploited the techniques, associated with the evolution operator method, to prove the existence of a one-to one correspondence between the wave function of a free particle and those of a particle ruled by a quadratic Hamiltonian [it

  12. Force of habit: shrubs, trees and contingent evolution of wood anatomical diversity using Croton (Euphorbiaceae) as a model system

    Science.gov (United States)

    Rafael Arévalo; Benjamin W. van Ee; Ricarda Riina; Paul E. Berry; Alex C. Wiedenhoeft

    2017-01-01

    Background and Aims Wood is a major innovation of land plants, and is usually a central component of the body plan for two major plant habits: shrubs and trees. Wood anatomical syndromes vary between shrubs and trees, but no prior work has explicitly evaluated the contingent evolution of wood anatomical diversity in the context...

  13. Pile Driving

    Science.gov (United States)

    1987-01-01

    Machine-oriented structural engineering firm TERA, Inc. is engaged in a project to evaluate the reliability of offshore pile driving prediction methods to eventually predict the best pile driving technique for each new offshore oil platform. Phase I Pile driving records of 48 offshore platforms including such information as blow counts, soil composition and pertinent construction details were digitized. In Phase II, pile driving records were statistically compared with current methods of prediction. Result was development of modular software, the CRIPS80 Software Design Analyzer System, that companies can use to evaluate other prediction procedures or other data bases.

  14. A new force emerges from the dark side: evidence is growing that an intrinsic property of the universe is helping to drive its expansion

    CERN Multimedia

    Cookson, C

    2003-01-01

    "Astronomical surveys over the past five years have forced cosmologists to conclude that ordinary matter - in the form of familiar stars, planets and interstellar dust or more exotic objects, such as quasars and neutron stars - makes up only 4 per cent of the universe" (1 page).

  15. Evolution of a Western Arctic Ice Ocean Boundary Layer and Mixed Layer Across a Developing Thermodynamically Forced Marginal Ice Zone

    Science.gov (United States)

    2016-09-01

    heat and momentum transfer with the ice-ocean interface. These two observations demonstrate the intricate interplay between momentum, heat , and...summer evolution events: 1. Modulated shortwave radiative input to the ocean 2. Shoaled the ocean boundary layer increasing ocean heat storage 3... transfer in a stratified oceanic boundary layer. J. Geophys. Res., 92(C7), 6977–7986, doi:10.1029/JC092iC07p06977. McPhee, M. G., 1992: Turbulent heat

  16. Force of habit: shrubs, trees and contingent evolution of wood anatomical diversity using Croton (Euphorbiaceae) as a model system.

    Science.gov (United States)

    Arévalo, Rafael; van Ee, Benjamin W; Riina, Ricarda; Berry, Paul E; Wiedenhoeft, Alex C

    2017-03-01

    Wood is a major innovation of land plants, and is usually a central component of the body plan for two major plant habits: shrubs and trees. Wood anatomical syndromes vary between shrubs and trees, but no prior work has explicitly evaluated the contingent evolution of wood anatomical diversity in the context of these plant habits. Phylogenetic comparative methods were used to test for contingent evolution of habit, habitat and wood anatomy in the mega-diverse genus Croton (Euphorbiaceae), across the largest and most complete molecular phylogeny of the genus to date. Plant habit and habitat are highly correlated, but most wood anatomical features correlate more strongly with habit. The ancestral Croton was reconstructed as a tree, the wood of which is inferred to have absent or indistinct growth rings, confluent-like axial parenchyma, procumbent ray cells and disjunctive ray parenchyma cell walls. The taxa sampled showed multiple independent origins of the shrub habit in Croton , and this habit shift is contingent on several wood anatomical features (e.g. similar vessel-ray pits, thick fibre walls, perforated ray cells). The only wood anatomical trait correlated with habitat and not habit was the presence of helical thickenings in the vessel elements of mesic Croton . Plant functional traits, individually or in suites, are responses to multiple and often confounding contexts in evolution. By establishing an explicit contingent evolutionary framework, the interplay between habit, habitat and wood anatomical diversity was dissected in the genus Croton . Both habit and habitat influence the evolution of wood anatomical characters, and conversely, the wood anatomy of lineages can affect shifts in plant habit and habitat. This study hypothesizes novel putatively functional trait associations in woody plant structure that could be further tested in a variety of other taxa. Published by Oxford University Press on behalf of the Annals of Botany Company 2017. This work is

  17. Control rod drive

    International Nuclear Information System (INIS)

    Hawke, B.C.

    1986-01-01

    A reactor core, one or more control rods, and a control rod drive are described for selectively inserting and withdrawing the one or more control rods into and from the reactor core, which consists of: a support structure secured beneath the reactor core; control rod positioning means supported by the support structure for movably supporting the control rod for movement between a lower position wherein the control rod is located substantially beneath the reactor core and an upper position wherein at least an upper portion of the control rod extends into the reactor core; transmission means; primary drive means connected with the control rod positioning means by the transmission means for positioning the control rod under normal operating conditions; emergency drive means for moving the control rod from the lower position to the upper position under emergency conditions, the emergency drive means including a weight movable between an upper and a lower position, means for movably supporting the weight, and means for transmitting gravitational force exerted on the weight to the control rod positioning means to move the control rod upwardly when the weight is pulled downwardly by gravity; the transmission means connecting the control rod positioning means with the emergency drive means so that the primary drive means effects movement of the weight and the control rod in opposite directions under normal conditions, thus providing counterbalancing to reduce the force required for upward movement of the control rod under normal conditions; and restraint means for restraining the fall of the weight under normal operating conditions and disengaging the primary drive means to release the weight under emergency conditions

  18. Evolution operators and transformation of states under uniform and an/or elastic forces into free particle states

    Energy Technology Data Exchange (ETDEWEB)

    Dattoli, G.; Torre, A. [ENEA, Centro Ricerche Frascati, Rome (Italy). Dipt. Innovazione

    1999-07-01

    In this paper are exploited the techniques, associated with the evolution operator method, to prove the existence of a one-to one correspondence between the wave function of a free particle and those of a particle ruled by a quadratic Hamiltonian. [Italian] Le tecniche associate al metodo dell'operatore di evoluzione vengono utilizzate per dimostrare l'esistenza di una corrispondenza biunivoca tra la funzione d'onda di una particella libera e quella di una particella soggetta ad un potenziale armonico.

  19. Impaired Driving

    Science.gov (United States)

    ... Get the Facts What Works: Strategies to Increase Car Seat and Booster Seat ... narcotics. 3 That’s one percent of the 111 million self-reported episodes of alcohol-impaired driving among U.S. ...

  20. Dual role of an ac driving force and the underlying two distinct order–disorder transitions in the vortex phase diagram of Ca3Ir4Sn13

    International Nuclear Information System (INIS)

    Kumar, Santosh; Singh, Ravi P.; Thamizhavel, A.; Tomy, C.V.; Grover, A.K.

    2014-01-01

    Highlights: • This work pertains to new findings related to a broad SMP anomaly. • Broad SMP prima facie encompasses two phase transformations in vortex matter. • We demarcated two phase boundaries pertaining to order–disorder transitions which have quasi first-order nature. - Abstract: We present distinct demarcation of the Bragg glass (BG) to multi-domain vortex glass (VG) transition line and the eventual amorphization of the VG phase in a weakly pinned single crystal of the superconducting compound Ca 3 Ir 4 Sn 13 on the basis of comprehension of the different yields about the second magnetization peak (SMP) anomaly in the dc magnetization and the corresponding anomalous feature in the ac susceptibility measurements. The shaking by a small ac magnetic field, inevitably present in the ac susceptibility measurements, is seen to result in contrasting responses in two different portions of the field-temperature (H, T) phase space of the multi-domain VG. In one of the portions, embracing the BG to VG transition across the onset of the SMP anomaly, the ac drive is surprisingly seen to assist the transformation of the well ordered BG phase to a lesser ordered VG phase. The BG phase exists as a superheated state over a small portion of the VG space and this attests to the first order nature of the BG to VG transition

  1. Sexual antagonism and meiotic drive cause stable linkage disequilibrium and favour reduced recombination on the X chromosome.

    Science.gov (United States)

    Rydzewski, W T; Carioscia, S A; Liévano, G; Lynch, V D; Patten, M M

    2016-06-01

    Sexual antagonism and meiotic drive are sex-specific evolutionary forces with the potential to shape genomic architecture. Previous theory has found that pairing two sexually antagonistic loci or combining sexual antagonism with meiotic drive at linked autosomal loci augments genetic variation, produces stable linkage disequilibrium (LD) and favours reduced recombination. However, the influence of these two forces has not been examined on the X chromosome, which is thought to be enriched for sexual antagonism and meiotic drive. We investigate the evolution of the X chromosome under both sexual antagonism and meiotic drive with two models: in one, both loci experience sexual antagonism; in the other, we pair a meiotic drive locus with a sexually antagonistic locus. We find that LD arises between the two loci in both models, even when the two loci freely recombine in females and that driving haplotypes will be enriched for male-beneficial alleles, further skewing sex ratios in these populations. We introduce a new measure of LD, Dz', which accounts for population allele frequencies and is appropriate for instances where these are sex specific. Both models demonstrate that natural selection favours modifiers that reduce the recombination rate. These results inform observed patterns of congealment found on driving X chromosomes and have implications for patterns of natural variation and the evolution of recombination rates on the X chromosome. © 2016 European Society For Evolutionary Biology. Journal of Evolutionary Biology © 2016 European Society For Evolutionary Biology.

  2. Activation of lysosomal P2X4 by ATP transported into lysosomes via VNUT/SLC17A9 using V‐ATPase generated voltage gradient as the driving force

    Science.gov (United States)

    Zhong, Xi Zoë; Cao, Qi; Sun, Xue

    2016-01-01

    Key points SLC17A9 proteins function as a lysosomal ATP transporter responsible for lysosomal ATP accumulation.P2X4 receptors act as lysosomal ion channels activated by luminal ATP.SLC17A9‐mediated ATP transport across the lysosomal membrane is suppressed by Bafilomycin A1, the V‐ATPase inhibitor.SLC17A9 mainly uses voltage gradient but not pH gradient generated by the V‐ATPase as the driving force to transport ATP into the lysosome to activate P2X4. Abstract The lysosome contains abundant ATP which plays important roles in lysosome functions and in cell signalling. Recently, solute carrier family 17 member 9 (SLC17A9, also known as VNUT for vesicular nucleotide transporter) proteins were suggested to function as a lysosomal ATP transporter responsible for lysosomal ATP accumulation, and P2X4 receptors were suggested to be lysosomal ion channels that are activated by luminal ATP. However, the molecular mechanism of SLC17A9 transporting ATP and the regulatory mechanism of lysosomal P2X4 are largely unknown. In this study, we report that SLC17A9‐mediated ATP transport across lysosomal membranes is suppressed by Bafilomycin A1, the V‐ATPase inhibitor. By measuring P2X4 activity, which is indicative of ATP transport across lysosomal membranes, we further demonstrated that SLC17A9 mainly uses voltage gradient but not pH gradient as the driving force to transport ATP into lysosomes. This study provides a molecular mechanism for lysosomal ATP transport mediated by SLC17A9. It also suggests a regulatory mechanism of lysosomal P2X4 by SLC17A9. PMID:27477609

  3. Influence of certain forces on evolution of synonymous codon usage bias in certain species of three basal orders of aquatic insects.

    Science.gov (United States)

    Selva Kumar, C; Nair, Rahul R; Sivaramakrishnan, K G; Ganesh, D; Janarthanan, S; Arunachalam, M; Sivaruban, T

    2012-12-01

    Forces that influence the evolution of synonymous codon usage bias are analyzed in six species of three basal orders of aquatic insects. The rationale behind choosing six species of aquatic insects (three from Ephemeroptera, one from Plecoptera, and two from Odonata) for the present analysis is based on phylogenetic position at the basal clades of the Order Insecta facilitating the understanding of the evolution of codon bias and of factors shaping codon usage patterns in primitive clades of insect lineages and their subtle differences in some of their ecological and environmental requirements in terms of habitat-microhabitat requirements, altitudinal preferences, temperature tolerance ranges, and consequent responses to climate change impacts. The present analysis focuses on open reading frames of the 13 protein-coding genes in the mitochondrial genome of six carefully chosen insect species to get a comprehensive picture of the evolutionary intricacies of codon bias. In all the six species, A and T contents are observed to be significantly higher than G and C, and are used roughly equally. Since transcription hypothesis on codon usage demands A richness and T poorness, it is quite likely that mutation pressure may be the key factor associated with synonymous codon usage (SCU) variations in these species because the mutation hypothesis predicts AT richness and GC poorness in the mitochondrial DNA. Thus, AT-biased mutation pressure seems to be an important factor in framing the SCU variation in all the selected species of aquatic insects, which in turn explains the predominance of A and T ending codons in these species. This study does not find any association between microhabitats and codon usage variations in the mitochondria of selected aquatic insects. However, this study has identified major forces, such as compositional constraints and mutation pressure, which shape patterns of codon usage in mitochondrial genes in the primitive clades of insect lineages.

  4. Heavy metal(loid)s and organic contaminants in groundwater in the Pearl River Delta that has undergone three decades of urbanization and industrialization: Distributions, sources, and driving forces.

    Science.gov (United States)

    Huang, Guanxing; Zhang, Ming; Liu, Chunyan; Li, Liangping; Chen, Zongyu

    2018-09-01

    Urbanization and industrialization have increased groundwater resource demands, and may drive the change of heavy metal(loid)s and organic chemicals in groundwater in the Pearl River Delta (PRD), southern China. Thus, a comprehensive understanding of the distributions, sources, and driving forces of heavy metal(loid)s and organic chemicals in groundwater in the PRD is vital for water resource management in this region. In this study, eight heavy metal(loid)s and fifty-five organic chemicals in groundwater across the PRD were investigated. The results show that undrinkable groundwater related to heavy metal(loid)s was mainly due to high concentrations of Fe (19.3%) and As (6.8%). Eighteen organic contaminants were detected in groundwater in the PRD, where the most frequently detected organic contaminant was naphthalene, and its detection rate was 2.51%. In 5.3% of all groundwater samples, one or more organic contaminants were found. All detected organic contaminants, except ones without allowable limits, in groundwater were at concentrations below allowable limits of China. The mean concentrations of heavy metal(loid)s in granular aquifers were higher than those in fissured and karst aquifers, especially for Fe and As. Except Se, the mean concentrations of other heavy metal(loid)s and the frequency of detection of organic contaminants in groundwater in urbanized and peri-urban areas were higher than those in non-urbanized areas, especially for Hg, Co, and organic contaminants. Fe, As, and Se in groundwater mainly originated from the release of Fe/As/Se rich sediments. The former two were driven by reduction reactions, while the latter was driven by oxidation resulting from the infiltration of NO 3 - . In contrast, other five heavy metal(loid)s and organic contaminants in groundwater mainly originated from the anthropogenic sources, such as the infiltration of industrial sewage. It is evident that urbanization and industrialization are two powerful driving forces for

  5. Sexual selection on male size drives the evolution of male-biased sexual size dimorphism via the prolongation of male development.

    Science.gov (United States)

    Rohner, Patrick T; Blanckenhorn, Wolf U; Puniamoorthy, Nalini

    2016-06-01

    Sexual size dimorphism (SSD) arises when the net effects of natural and sexual selection on body size differ between the sexes. Quantitative SSD variation between taxa is common, but directional intraspecific SSD reversals are rare. We combined micro- and macroevolutionary approaches to study geographic SSD variation in closely related black scavenger flies. Common garden experiments revealed stark intra- and interspecific variation: Sepsis biflexuosa is monomorphic across the Holarctic, while S. cynipsea (only in Europe) consistently exhibits female-biased SSD. Interestingly, S. neocynipsea displays contrasting SSD in Europe (females larger) and North America (males larger), a pattern opposite to the geographic reversal in SSD of S. punctum documented in a previous study. In accordance with the differential equilibrium model for the evolution of SSD, the intensity of sexual selection on male size varied between continents (weaker in Europe), whereas fecundity selection on female body size did not. Subsequent comparative analyses of 49 taxa documented at least six independent origins of male-biased SSD in Sepsidae, which is likely caused by sexual selection on male size and mediated by bimaturism. Therefore, reversals in SSD and the associated changes in larval development might be much more common and rapid and less constrained than currently assumed. © 2016 The Author(s). Evolution © 2016 The Society for the Study of Evolution.

  6. Predation as the primary selective force in recurrent evolution of gigantism in Poecilozonites land snails in Quaternary Bermuda

    Science.gov (United States)

    Olson, Storrs L.; Hearty, Paul J.

    2010-01-01

    During the last half million years, pulses of gigantism in the anagenetic lineage of land snails of the subgenus Poecilozonites on Bermuda were correlated with glacial periods when lower sea level resulted in an island nearly an order of magnitude larger than at present. During those periods, the island was colonized by large vertebrate predators that created selection pressure for large size and rapid growth in the snails. Extreme reduction in land area from rising seas, along with changes in ecological conditions at the onset of interglacial episodes, marked extinction events for large predators, after which snails reverted to much smaller size. The giant snails were identical in morphology during the last two glacials when the predators included a large flightless rail Rallus recessus (marine isotope stages (MIS) 4-2) and a crane Grus latipes and a duck Anas pachysceles (MIS 6). In a preceding glacial period (MIS 10), when the fauna also included the tortoise Hesperotestudo bermudae, the snails were not only large, but the shells were much thicker, presumably to prevent crushing by tortoises. Evolution of Poecilozonites provides an outstanding example of dramatic morphological change in response to environmental pressures in the absence of cladogenesis. PMID:20554560

  7. Vegetation dynamics and its driving forces from climate change and human activities in the Three-River Source Region, China from 1982 to 2012

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Ying; Zhang, Chaobin; Wang, Zhaoqi; Chen, Yizhao; Gang, Chengcheng [School of Life Science, Nanjing University, Xianlin Road 163, Qixia District, Nanjing, 210046 (China); An, Ru [School of Earth Science and Engineering, Hohai University, Xikang Road 129, Nanjing, 210098 (China); Li, Jianlong, E-mail: lijianlongnju@163.com [School of Life Science, Nanjing University, Xianlin Road 163, Qixia District, Nanjing, 210046 (China)

    2016-09-01

    The Three-River Source Region (TRSR), a region with key importance to the ecological security of China, has undergone climate changes and a shift in human activities driven by a series of ecological restoration projects in recent decades. To reveal the spatiotemporal dynamics of vegetation dynamics and calculate the contributions of driving factors in the TRSR across different periods from 1982 to 2012, net primary productivity (NPP) estimated using the Carnegie–Ames–Stanford approach model was used to assess the status of vegetation. The actual effects of different climatic variation trends on interannual variation in NPP were analyzed. Furthermore, the relationships of NPP with different climate factors and human activities were analyzed quantitatively. Results showed the following: from 1982 to 2012, the average NPP in the study area was 187.37 g cm{sup −2} yr{sup −1}. The average NPP exhibited a fluctuation but presented a generally increasing trend over the 31-year study period, with an increase rate of 1.31 g cm{sup −2} yr{sup −2}. During the entire study period, the average contributions of temperature, precipitation, and solar radiation to NPP interannual variation over the entire region were 0.58, 0.73, and 0.09 g cm{sup −2} yr{sup −2}, respectively. Radiation was the climate factor with the greatest influence on NPP interannual variation. The factor that restricted NPP increase changed from temperature and radiation to precipitation. The average contributions of climate change and human activities to NPP interannual variation were 1.40 g cm{sup −2} yr{sup −2} and − 0.08 g cm{sup −2} yr{sup −2}, respectively. From 1982 to 2000, the general climate conditions were favorable to vegetation recovery, whereas human activities had a weaker negative impact on vegetation growth. From 2001 to 2012, climate conditions began to have a negative impact on vegetation growth, whereas human activities made a favorable impact on vegetation

  8. Vegetation dynamics and its driving forces from climate change and human activities in the Three-River Source Region, China from 1982 to 2012

    International Nuclear Information System (INIS)

    Zhang, Ying; Zhang, Chaobin; Wang, Zhaoqi; Chen, Yizhao; Gang, Chengcheng; An, Ru; Li, Jianlong

    2016-01-01

    The Three-River Source Region (TRSR), a region with key importance to the ecological security of China, has undergone climate changes and a shift in human activities driven by a series of ecological restoration projects in recent decades. To reveal the spatiotemporal dynamics of vegetation dynamics and calculate the contributions of driving factors in the TRSR across different periods from 1982 to 2012, net primary productivity (NPP) estimated using the Carnegie–Ames–Stanford approach model was used to assess the status of vegetation. The actual effects of different climatic variation trends on interannual variation in NPP were analyzed. Furthermore, the relationships of NPP with different climate factors and human activities were analyzed quantitatively. Results showed the following: from 1982 to 2012, the average NPP in the study area was 187.37 g cm"−"2 yr"−"1. The average NPP exhibited a fluctuation but presented a generally increasing trend over the 31-year study period, with an increase rate of 1.31 g cm"−"2 yr"−"2. During the entire study period, the average contributions of temperature, precipitation, and solar radiation to NPP interannual variation over the entire region were 0.58, 0.73, and 0.09 g cm"−"2 yr"−"2, respectively. Radiation was the climate factor with the greatest influence on NPP interannual variation. The factor that restricted NPP increase changed from temperature and radiation to precipitation. The average contributions of climate change and human activities to NPP interannual variation were 1.40 g cm"−"2 yr"−"2 and − 0.08 g cm"−"2 yr"−"2, respectively. From 1982 to 2000, the general climate conditions were favorable to vegetation recovery, whereas human activities had a weaker negative impact on vegetation growth. From 2001 to 2012, climate conditions began to have a negative impact on vegetation growth, whereas human activities made a favorable impact on vegetation recovery. - Highlights: • Partitioned the

  9. Driving things

    DEFF Research Database (Denmark)

    Nevile, Maurice Richard

    2015-01-01

    I explore how participants organise involvement with objects brought into the car, relative to the demands of driving and social activity. Objects in cars commonly include phones or other technologies, food, body care products, texts, clothing, bags and carry items, toys, and even animals...... 2004, Haddington et al. 2012). I focus here especially on how the practical and interactional work of locating, seeing, placing, handling, hearing, and relinquishing, is ordered and accomplished relative to the emerging and contingent demands of both driving and social participation......, such that involvement with objects is constituted as secondary to driving in a multiactivity setting (e.g. Haddington et al. 2014). We see how events with, for, of, and even by objects can occur as predictable, planned and even designed for (e.g. changing glasses, applying body lotion), or might be unexpected...

  10. A high force of plasmodium vivax blood-stage infection drives the rapid acquisition of immunity in papua new guinean children.

    Directory of Open Access Journals (Sweden)

    Cristian Koepfli

    Full Text Available When both parasite species are co-endemic, Plasmodium vivax incidence peaks in younger children compared to P. falciparum. To identify differences in the number of blood stage infections of these species and its potential link to acquisition of immunity, we have estimated the molecular force of blood-stage infection of P. vivax ((molFOB, i.e. the number of genetically distinct blood-stage infections over time, and compared it to previously reported values for P. falciparum.P. vivax (molFOB was estimated by high resolution genotyping parasites in samples collected over 16 months in a cohort of 264 Papua New Guinean children living in an area highly endemic for P. falciparum and P. vivax. In this cohort, P. vivax episodes decreased three-fold over the age range of 1-4.5 years.On average, children acquired 14.0 new P. vivax blood-stage clones/child/year-at-risk. While the incidence of clinical P. vivax illness was strongly associated with mol FOB (incidence rate ratio (IRR = 1.99, 95% confidence interval (CI95 [1.80, 2.19], (molFOB did not change with age. The incidence of P. vivax showed a faster decrease with age in children with high (IRR = 0.49, CI95 [0.38, 0.64] p<0.001 compared to those with low exposure (IRR = 0.63, CI95[0.43, 0.93] p = 0.02.P. vivax (molFOB is considerably higher than P. falciparum (molFOB (5.5 clones/child/year-at-risk. The high number of P. vivax clones that infect children in early childhood contribute to the rapid acquisition of immunity against clinical P. vivax malaria.

  11. Transactional Infrastructure of the Economy: the Evolution of Concepts and Synthesis of Definitions

    OpenAIRE

    Maruschak Irina Valeryevna

    2017-01-01

    The overview of evolution of market infrastructure concepts is provided, the first concepts of institutional infrastructure are revealed in the paper. Evolutionarily developed narrowing of essence of infrastructure in connection with the priority analysis of its physical (material and technological) components is proved. It ignores the fact that transactional resources, being drivers (driving forces) of economic systems evolution, in turn evolve, becoming harder and harder, combining increase...

  12. The evidences of progressive pressurization of volcanic conduit as driving forces of unrest phenomena analyzed via modelling of multiplatform geodetic measurements: Fernandina (GALAPAGOS) and Maunaloa (HAWAII) case studies

    Science.gov (United States)

    Pepe, Susi; Castaldo, Raffaele; Casu, Francesco; D'Auria, Luca; De Luca, Claudio; De Novellis, Vincenzo; Solaro, Giuseppe; Tizzani, Pietro

    2017-04-01

    We investigated the source of the ground deformation pattern affecting the Mauna Loa (Hawaii) and Fernandina (Galapagos) volcanoes by jointly exploiting different dataset collected by both GPS and multiplatform and multiorbit SAR sensors. We exploited the advanced Differential SAR Interferometry (DInSAR) techniques to analyze unrest episode in two different geodynamics context. Our main goal is the understanding of the relationship among the spatio-temporal evolution of the ground deformation field and the temporal volumetric variation of the detected geodetic source during the uplift phenomena. We highlight the huge opportunity in understanding volcano unrest phenomena offered by the joint use of remote sensing data and inversion procedures: this prospect is particularly relevant for the analysis of uplift events, when other geophysical measurements are not available. For Mauna Loa (Hawaii) and Fernandina (Galapagos) volcanoes, the performed statistic analysis support the source pipe-like as the more suitable geometry to explain the unrest phenomena in which magmatic masses intrude in volcanic conduits. In particular, the deformation time series achieved at MounaLoa volcano are achieved by 23 GPS permanent stations of the Hawaii surveillance network, processed by Nevada Geodetic Laboratory, 7 SAR dataset acquired from ascending and descending orbits, with different look angles and along different tracks, by the C-Band Envisat satellite along the 2003 - 2010 time period for a total of 189 SAR imagery. Moreover, we exploited 2 dataset collected from ascending and descending passes by the X-Band Cosmo Sky-Med constellation during the 2012 - 2015 time span . These SAR datasets have been processed through the advanced DInSAR technique referred to as P-SBAS (De Luca et al., 2016), which allows us to retrieve the Line of Sight (LOS) projection of the surface deformation and analyze its temporal evolution by generating displacement time series. Starting this data

  13. Quantifying the Forcing Factors Responsible for the Tectono-Geomorphological Evolution of Neogene Rift Basins, Baja California

    Science.gov (United States)

    El-Sobky, H. F.; Dorobek, S. L.

    2005-12-01

    The Gulf of California and its surrounding land areas provide a classic example of recently rifted continental lithosphere, where back-arc stretching of a continental volcanic arc has culminated in the ongoing seafloor spreading that characterizes the present-day axis of the gulf. The recent tectonic history of eastern Baja California, which includes most of the land area eastward of the main drainage divide that extends north-south along the length of the peninsula, has been dominated by oblique rifting that began at about 5 Ma. Thus, extensional tectonics, bedrock lithology, long-term climatic changes, and evolving surface processes have controlled the tectono-geomorphological evolution of the eastern part of the peninsula since 5 Ma. No previous studies, however, examined the effect of these combined factors on the current tectono-geomorphological characteristics of eastern Baja California. We assume that although long-term climate may have changed along the peninsula over the last several million years, precipitation amounts are likely to have changed in a similar way along the entire length of the peninsula, regardless of the long-term climatic trend. This suggests that climatic variation can be largely ruled out as an explanation for the geomorphologic variability between basins. In an attempt to quantify the factors that affected the geomorphologic development along the eastern side of Baja California, thirty-four drainage basins were extracted from a 15-m-resolution absolute digital elevation model (DEM). The stacked-vector method was applied to utilize the different terrain attributes (e.g., hillshaded relief, aspect, slope, etc.) for supervised classification of bedrock lithologies using object-oriented techniques. Stream-length gradient indices were then measured for the main stream in each of the basins. Bedrock lithologies and alluvium were plotted along the stream profiles to identify any relationship between lithology, structure, and stream gradient

  14. Mechanistically Distinct Pathways of Divergent Regulatory DNA Creation Contribute to Evolution of Human-Specific Genomic Regulatory Networks Driving Phenotypic Divergence of Homo sapiens.

    Science.gov (United States)

    Glinsky, Gennadi V

    2016-09-19

    Thousands of candidate human-specific regulatory sequences (HSRS) have been identified, supporting the hypothesis that unique to human phenotypes result from human-specific alterations of genomic regulatory networks. Collectively, a compendium of multiple diverse families of HSRS that are functionally and structurally divergent from Great Apes could be defined as the backbone of human-specific genomic regulatory networks. Here, the conservation patterns analysis of 18,364 candidate HSRS was carried out requiring that 100% of bases must remap during the alignments of human, chimpanzee, and bonobo sequences. A total of 5,535 candidate HSRS were identified that are: (i) highly conserved in Great Apes; (ii) evolved by the exaptation of highly conserved ancestral DNA; (iii) defined by either the acceleration of mutation rates on the human lineage or the functional divergence from non-human primates. The exaptation of highly conserved ancestral DNA pathway seems mechanistically distinct from the evolution of regulatory DNA segments driven by the species-specific expansion of transposable elements. Genome-wide proximity placement analysis of HSRS revealed that a small fraction of topologically associating domains (TADs) contain more than half of HSRS from four distinct families. TADs that are enriched for HSRS and termed rapidly evolving in humans TADs (revTADs) comprise 0.8-10.3% of 3,127 TADs in the hESC genome. RevTADs manifest distinct correlation patterns between placements of human accelerated regions, human-specific transcription factor-binding sites, and recombination rates. There is a significant enrichment within revTAD boundaries of hESC-enhancers, primate-specific CTCF-binding sites, human-specific RNAPII-binding sites, hCONDELs, and H3K4me3 peaks with human-specific enrichment at TSS in prefrontal cortex neurons (P sapiens is driven by the evolution of human-specific genomic regulatory networks via at least two mechanistically distinct pathways of creation of

  15. Control rod drive mechanism

    International Nuclear Information System (INIS)

    Mizuno, Katsuyuki.

    1976-01-01

    Object: To restrict the reduction in performance due to stress corrosion cracks by making use of condensate produced in a turbine steam condenser. Structure: Water produced in a turbine steam condenser is forced into a condensed water desalting unit by low pressure condensate pump. The condensate is purified and then forced by a high pressure condensate pump into a feedwater heater for heating before it is returned to the reactor by a feedwater pump. Part of the condensate issuing from the condensate desalting unit is branched from the remaining portion at a point upstream the pump and is withdrawn into a control rod drive water pump after passing through a motordriven bypass valve, an orifice and a condenser water level control valve, is pressurized in the control rod drive water desalting unit and supplied to a control rod drive water pressure system. The control rod is vertically moved by the valve operation of the water pressure system. Since water of high oxygen concentration does not enter during normal operation, it is possible to prevent the stress cracking of the stainless steel apparatus. (Nakamura, S.)

  16. Control rod drive

    International Nuclear Information System (INIS)

    Watando, Kosaku; Tanaka, Yuzo; Mizumura, Yasuhiro; Hosono, Kazuya.

    1975-01-01

    Object: To provide a simple and compact construction of an apparatus for driving a drive shaft inside with a magnetic force from the outside of the primary system water side. Structure: The weight of a plunger provided with an attraction plate is supported by a plunger lift spring means so as to provide a buffer action at the time of momentary movement while also permitting the load on lift coil to be constituted solely by the load on the drive shaft. In addition, by arranging the attraction plate and lift coil so that they face each other with a small gap there-between, it is made possible to reduce the size and permit efficient utilization of the attracting force. Because of the small size, cooling can be simply carried out. Further, since there is no mechanical penetration portion, there is no possibility of leakage of the primary system water. Furthermore, concentration of load on a latch pin is prevented by arranging so that with a structure the load of the control rod to be directly beared through the scrum latch. (Kamimura, M.)

  17. Structure and optical properties of Ge/Si quantum dots formed by driving the evolution of Ge thin films via thermal annealing

    Science.gov (United States)

    Shu, Qijiang; Yang, Jie; Chi, Qingbin; Sun, Tao; Wang, Chong; Yang, Yu

    2018-04-01

    Ge/Si quantum dots (QDs) are fabricated by driving the transformation of a Ge thin film-deposited using the direct current (DC) magnetron sputtering technique by controlling the subsequent in situ annealing processes. The experimental results indicate that, with the increase in annealing temperature, the volume of Ge QDs increases monotonically, while the QD density initially increases then decreases. The maximal QD density can reach 1.1 × 1011 cm‑2 after a 10 min annealing at 650 °C. The Ge–Ge peak of Ge QDs obtained by Raman spectroscopy initially undergoes a blue shift and then a red shift with increasing annealing temperature. This behavior results from the competition between the dislocation and the strain relaxation in QDs. Concurrently, a series of photoelectric detectors are fabricated to evaluate the photoelectric performance of these annealed Ge QD samples. A high-photoelectricity response is demonstrated in the QD sample annealed at 650 °C. Our results pave a promising way for whole-silicon-material optical-electronic integration based on a simple and practicable fabrication method.

  18. Community Drive

    DEFF Research Database (Denmark)

    Magnussen, Rikke

    2018-01-01

    Schools and educational institutions are challenged by not adequately educating students for independent knowledge collaboration and solving of complex societal challenges (Bundsgaard & Hansen, 2016; Slot et al., 2017). As an alternative strategy to formal learning has Community-driven research...... opportunity to break boundaries between research institutions and surrounding communities through the involvement of new types of actors, knowledge forms and institutions (OECD, 2011). This paper presents the project Community Drive a three year cross disciplinary community-driven game– and data-based project....... In the paper we present how the project Community Drive initiated in May 2018 is based on results from pilot projects conducted from 2014 – 2017. Overall these studies showed that it is a strong motivational factor for students to be given the task to change their living conditions through redesign...

  19. [Study on the types and water pollution driving forces of the typical and medium-small-sized cities in the southern China based on the analysis of water environment].

    Science.gov (United States)

    Jiao, Shi-Xing; Wang, La-Chun; Huo, Yu; Chen, Chang-Chun; Teng, Juan

    2009-07-15

    According to the major pollution sources of urban water environment, 10 indexes such as industrial sewage quantity were closen to establish evaluation indexes system about the types and influencing factors of the typical and medium-small-sized cities in the southern China. Case studies of 16 typical and medium-small-sized cities were taken in Jiangsu, Zhejiang, Hubei and Anhui provinces. Combined with SPSS 11.0 cluster analysis results, city types were divided in reference to the values of water resources comprehensive pollution indexes and economical development indexes. The driving forces about city water environment pollution were studied by principal component analysis method. The result indicates that the 16 cities belong to two categories and four sub-categories, which are rich economy as well as light pollution of water environment and poor economy as well as heavy pollution of water environment. The influencing factors of water environment pollution are in sequence of industrial water pollution, agricultural no-point source pollution and urban domestic water pollution. The main factors of water environment pollution influenced I category cities, II as well as IV category cities and III category cities are industrial water pollution, urban domestic pollution and agricultural no-point source pollution respectively.

  20. Electric drives

    Energy Technology Data Exchange (ETDEWEB)

    1986-10-01

    Several electric vehicles have been tested in long-term tests, i.e. an electric passenger car (maximum speed 115 km/h) and several busses for use in pedestrians' zones, spas, airports, natural reserves, and urban transportation (DUO busses). The ICE high-speed train is discussed in some detail, i.e. its aeroacoustic and aerodynamic design, running gear, computer-controlled drives and brakes, diagnostic systems, and electrical equipment. The Berlin Maglev system is mentioned as well as current inverters in rail vehicles. (HWJ).

  1. Temporal genomic evolution of bird sex chromosomes

    DEFF Research Database (Denmark)

    Wang, Zongji; Zhang, Jilin; Yang, Wei

    2014-01-01

    BACKGROUND: Sex chromosomes exhibit many unusual patterns in sequence and gene expression relative to autosomes. Birds have evolved a female heterogametic sex system (male ZZ, female ZW), through stepwise suppression of recombination between chrZ and chrW. To address the broad patterns and complex...... driving forces of Z chromosome evolution, we analyze here 45 newly available bird genomes and four species' transcriptomes, over their course of recombination loss between the sex chromosomes. RESULTS: We show Z chromosomes in general have a significantly higher substitution rate in introns and synonymous...... ('fast-Z' evolution). And species with a lower level of intronic heterozygosities tend to evolve even faster on the Z chromosome. Further analysis of fast-evolving genes' enriched functional categories and sex-biased expression patterns support that, fast-Z evolution in birds is mainly driven by genetic...

  2. [Mobile genetic elements in plant sex evolution].

    Science.gov (United States)

    Gerashchenkov, G A; Rozhnova, N A

    2010-11-01

    The most significant theories of the appearance and maintenance of sex are presented. However, in the overwhelming majority of existing theories, the problem of sex, which is the central problem of evolutionary biology, is considered primarily through the prism of reproductive features of living organisms, whereas the issue of molecular driving forces of sexual reproduction id restricted to the possible role of mobile genetic elements (MGEs) in the appearance of sexual reproduction. The structural and functional significance of MGEs in the genomic organization of plants is illustrated. It is shown that MGEs could act as important molecular drivers of sex evolution in plants. The involvement of MGEs in the formation of sex chromosomes and possible participation in seeds-without-sex reproduction (apomixis) is discussed. Thus, the hypothesis on the active MGE participation in sex evolution is in good agreement with the modern views on pathways and directions of sex evolution in plants.

  3. The community as a driving force.

    Science.gov (United States)

    1993-12-01

    A Workshop on Effective Strategies for Sustainable Community-based Family Planning (FP) and Maternal and Child Health (MCH) was held on October 14-23, 1993, as part of an Asian regional project focusing on women. Bangladesh, China, Laos, Nepal, the Philippines, and Viet Nam were represented at the workshop. The program introduced participants to effective community participation strategies in FP and MCH in Indonesia and allowed for the exchange of information. The UN Population Fund expressed support and encouragement for the exchange and recognition of Indonesia's government support for efforts at regional exchanges. Indonesia established integrated service posts or "Posyandu" in villages during the 1980s for women volunteers as health advocates. FP/MCH was later integrated in these health posts. The service posts aim to reduce infant mortality and maternal mortality through growth monitoring of children aged under five years, provision of FP, nutrition services for pregnant mothers, immunization, and monitoring of high-risk pregnancies. Trained volunteers and community people are aides to either government personnel or nongovernmental (NGO) workers. The Indonesian government FP program evolved from a program "for" the people, to "with" the people, and finally "by" the people. Fees for contraception, which are still below retail prices, are being introduced as a means of achieving sustainability. The government trains doctors and midwives in FP. NGOs such as Yayasan Kusuma Buana (YKB) in Jakarta provide a mix of quality services. YKB is active in promoting awareness of FP. Community outreach is achieved through mothers' classes, urban Posyandu services, and training of traditional birth attendants. The Indonesian Planned Parenthood Association maintains self-reliance programs in FP/MCH. Day-care centers and youth counseling centers are used in promoting FP/MCH. YKB methods were demonstrated for workshop participants (posters used in local shops and awareness activities for school health programs). Workshop participants were exposed to many activities in FP/MCH. Participants learned the importance of government commitment and the importance of people's acceptance that FP is necessary for improving the quality of life.

  4. Driving Force Based Design of Cyclic Distillation

    DEFF Research Database (Denmark)

    Nielsen, Rasmus Fjordbak; Huusom, Jakob Kjøbsted; Abildskov, Jens

    2017-01-01

    with mixed phase feeds. A range of binary test cases, benzene toluene, methanol water, and ethanol water, are evaluated. The advantage of the design approach in cyclic distillation is shown to be analogous to the advantages obtained in conventional continuous distillation, including a minimal utility...

  5. Amenity migration - driving force for rural development?

    Czech Academy of Sciences Publication Activity Database

    Bartoš, Michael; Kušová, Drahomíra; Těšitel, Jan

    2007-01-01

    Roč. 4, 3-4 (2007), s. 57-69 ISSN 1841-0375 R&D Projects: GA ČR(CZ) GA403/07/0714 Institutional research plan: CEZ:AV0Z60870520 Keywords : Amenity migration * tourism * rural development Subject RIV: AO - Sociology, Demography

  6. Thermodynamic driving force for rafting in superalloys

    CSIR Research Space (South Africa)

    Nabarro, FRN

    1996-08-01

    Full Text Available - and three-dimensional systems behave similarly. The initial plastic strain in gamma' is anelastic and in principle reversible. When the plastic strain exceeds m delta, platelets perpendicular to the stress axis are formed if the product sigma delta...

  7. The driving force role of ruthenacyclobutanes

    KAUST Repository

    Vummaleti, Sai V. C.

    2015-02-07

    DFT calculations have been used to determine the thermodynamic and kinetic preference for ruthenacyclobutanes resulting from the experimentally proposed interconversion pathways (olefin and alkylidene rotations) through the investigation of cross-metathesis reaction mechanism for neutral Grubbs catalyst, RuCl2(=CHEt)NHC (A), with ethylene and 1-butene as the substrates. Our results show that although the proposed interconversions are feasible due to the predicted low energy barriers (2-6 kcal/mol), the formation of ruthenacyclobutane is kinetically favored over the competitive reactions involving alkylidene rotations. In comparison with catalyst A, the reaction energy profile for cationic Piers catalyst [RuCl2(=CHPCy3)NHC+] (B) is more endothermic in nature with both ethylene and 1-butene substrates.

  8. The driving force role of ruthenacyclobutanes

    KAUST Repository

    Vummaleti, Sai V. C.; Cavallo, Luigi; Poater, Albert

    2015-01-01

    DFT calculations have been used to determine the thermodynamic and kinetic preference for ruthenacyclobutanes resulting from the experimentally proposed interconversion pathways (olefin and alkylidene rotations) through the investigation of cross-metathesis reaction mechanism for neutral Grubbs catalyst, RuCl2(=CHEt)NHC (A), with ethylene and 1-butene as the substrates. Our results show that although the proposed interconversions are feasible due to the predicted low energy barriers (2-6 kcal/mol), the formation of ruthenacyclobutane is kinetically favored over the competitive reactions involving alkylidene rotations. In comparison with catalyst A, the reaction energy profile for cationic Piers catalyst [RuCl2(=CHPCy3)NHC+] (B) is more endothermic in nature with both ethylene and 1-butene substrates.

  9. Tourism: spatial dimension and driving force

    OpenAIRE

    Lourenço, Nelson; Jorge, Rosário

    2003-01-01

    Spatial and socio-economic impacts of tourism have been quite significant in some regions, causing changes in the economic structure, stimulating some sectors and displacing others. Tourism creates pressures on different domains—natural resources and environment, the built environment, and hospitality and cultural resources. The tourism infrastructure has impacted on the existing social, economic, and environmental dynamics of Goan society. Some of the tourism-related influences are discu...

  10. Control rod drives

    International Nuclear Information System (INIS)

    Furumitsu, Yutaka.

    1981-01-01

    Purpose: To improve the reliability of a device for driving an LMFBR type reactor control rod by providing a buffer unit having a stationary electromagnetic coil and a movable electromagnetic coil in the device to thereby avord impact stress at scram time and to simplify the structure of the buffer unit. Constitution: A non-contact type buffer unit is constructed with a stationary electromagnetic coil, a cable for the stationary coil, a movable electromagnetic coil, a spring cable for the movable coil, and a backup coil spring or the like. Force produced at scram time is delivered without impact by the attracting or repelling force between the stationary coil and the movable coil of the buffer unit. Accordingly, since the buffer unit is of a non-contact type, there is no mechanical impact and thus no large impact stress, and as it has simple configuration, the reliability is improved and the maintenance can be conducted more easily. (Yoshihara, H.)

  11. Safe driving for teens

    Science.gov (United States)

    Driving and teenagers; Teens and safe driving; Automobile safety - teenage drivers ... months before taking friends as passengers. Teenage-related driving deaths occur more often in certain conditions. OTHER SAFETY TIPS FOR TEENS Reckless driving is still a ...

  12. Energizing porters by proton-motive force.

    Science.gov (United States)

    Nelson, N

    1994-11-01

    It is generally accepted that the chemistry of water was the most crucial determinant in shaping life on earth. Among the more important chemical features of water is its dissociation into protons and hydroxyl ions. The presence of relatively high proton concentrations in the ambient solution resulted in the evolution of proton pumps during the dawn of life on earth. These proton pumps maintained neutral pH inside the cells and generated electrochemical gradients of protons (proton-motive force) across their membranes. The existence of proton-motive force enabled the evolution of porters driven by it that are most probably among the more primitive porters in the world. The directionality of the substrate transport by the porters could be to both sides of the membranes because they can serve as proton symporters or antiporters. One of the most important subjects of this meeting is the mechanism by which proton-motive and other ion-motive forces drive the transport processes through porters. Is there a common mechanism of action for all proton-driven porters? Is there some common partial reaction by which we can identify the way that porters are energized by proton-motive force? Is there a common coupling between proton movement and uptake or secretion of certain molecules? Even a partial answer to one of these questions would advance our knowledge... or confusion. As my mentor Efraim Racker used to say: 'If you are not totally confused you do not understand the issue'.

  13. Adaptive evolution in ecological communities.

    Directory of Open Access Journals (Sweden)

    Martin M Turcotte

    Full Text Available Understanding how natural selection drives evolution is a key challenge in evolutionary biology. Most studies of adaptation focus on how a single environmental factor, such as increased temperature, affects evolution within a single species. The biological relevance of these experiments is limited because nature is infinitely more complex. Most species are embedded within communities containing many species that interact with one another and the physical environment. To understand the evolutionary significance of such ecological complexity, experiments must test the evolutionary impact of interactions among multiple species during adaptation. Here we highlight an experiment that manipulates species composition and tracks evolutionary responses within each species, while testing for the mechanisms by which species interact and adapt to their environment. We also discuss limitations of previous studies of adaptive evolution and emphasize how an experimental evolution approach can circumvent such shortcomings. Understanding how community composition acts as a selective force will improve our ability to predict how species adapt to natural and human-induced environmental change.

  14. Finite Element Analysis Of Influence Of Flank Wear Evolution On Forces In Orthogonal Cutting Of 42CrMo4 Steel

    Directory of Open Access Journals (Sweden)

    Madajewski Marek

    2017-01-01

    Full Text Available This paper presents analysis of flank wear influence on forces in orthogonal turning of 42CrMo4 steel and evaluates capacity of finite element model to provide such force values. Data about magnitude of feed and cutting force were obtained from measurements with force tensiometer in experimental test as well as from finite element analysis of chip formation process in ABAQUS/Explicit software. For studies an insert with complex rake face was selected and flank wear was simulated by grinding operation on its flank face. The aim of grinding inset surface was to obtain even flat wear along cutting edge, which after the measurement could be modeled with CAD program and applied in FE analysis for selected range of wear width. By comparing both sets of force values as function of flank wear in given cutting conditions FEA model was validated and it was established that it can be applied to analyze other physical aspects of machining. Force analysis found that progression of wear causes increase in cutting force magnitude and steep boost to feed force magnitude. Analysis of Fc/Ff force ratio revealed that flank wear has significant impact on resultant force in orthogonal cutting and magnitude of this force components in cutting and feed direction. Surge in force values can result in transfer of substantial loads to machine-tool interface.

  15. Finite Element Analysis Of Influence Of Flank Wear Evolution On Forces In Orthogonal Cutting Of 42CrMo4 Steel

    Science.gov (United States)

    Madajewski, Marek; Nowakowski, Zbigniew

    2017-01-01

    This paper presents analysis of flank wear influence on forces in orthogonal turning of 42CrMo4 steel and evaluates capacity of finite element model to provide such force values. Data about magnitude of feed and cutting force were obtained from measurements with force tensiometer in experimental test as well as from finite element analysis of chip formation process in ABAQUS/Explicit software. For studies an insert with complex rake face was selected and flank wear was simulated by grinding operation on its flank face. The aim of grinding inset surface was to obtain even flat wear along cutting edge, which after the measurement could be modeled with CAD program and applied in FE analysis for selected range of wear width. By comparing both sets of force values as function of flank wear in given cutting conditions FEA model was validated and it was established that it can be applied to analyze other physical aspects of machining. Force analysis found that progression of wear causes increase in cutting force magnitude and steep boost to feed force magnitude. Analysis of Fc/Ff force ratio revealed that flank wear has significant impact on resultant force in orthogonal cutting and magnitude of this force components in cutting and feed direction. Surge in force values can result in transfer of substantial loads to machine-tool interface.

  16. Specialization can drive the evolution of modularity.

    Directory of Open Access Journals (Sweden)

    Carlos Espinosa-Soto

    2010-03-01

    Full Text Available Organismal development and many cell biological processes are organized in a modular fashion, where regulatory molecules form groups with many interactions within a group and few interactions between groups. Thus, the activity of elements within a module depends little on elements outside of it. Modularity facilitates the production of heritable variation and of evolutionary innovations. There is no consensus on how modularity might evolve, especially for modules in development. We show that modularity can increase in gene regulatory networks as a byproduct of specialization in gene activity. Such specialization occurs after gene regulatory networks are selected to produce new gene activity patterns that appear in a specific body structure or under a specific environmental condition. Modules that arise after specialization in gene activity comprise genes that show concerted changes in gene activities. This and other observations suggest that modularity evolves because it decreases interference between different groups of genes. Our work can explain the appearance and maintenance of modularity through a mechanism that is not contingent on environmental change. We also show how modularity can facilitate co-option, the utilization of existing gene activity to build new gene activity patterns, a frequent feature of evolutionary innovations.

  17. Essential equivalence: the objectives and requirements of a stategic nuclear policy: a perspective on the evolution of US strategic nuclear policy, and an assessment of present and emerging US strategic policy and force stucture options

    International Nuclear Information System (INIS)

    Hughes, P.C.

    1979-01-01

    This study provides a discussion of the origins and evolution of US strategic nuclear policy, the objectives an requirements of US nuclear forces, and an assessment of present and emerging US stategic nuclear policy and force structure options. It identifies the distinctive phases of US strategic nuclear policy, the conditions of the military environments in which those policies were developed, the interaction of US-Soviet strategic force and arms control processes during these phases, and the domestic debates which have accompanied US strategic nuclear policy developments. In particular, the study focuses on the major contending views which continue to characterize the debate concerning US strategic nuclear policy. The study assesses the implications of the contending views represented in what is commonly referred to as the counterforce-countervalue debate, particularly as they relate to the perception of what constitutes a credible US deterrent posture, and the corresponding alternatives that these views bring with them for making US strategic nuclear policy and force structure decisions. The arms control process, in general, and SALT I and SALT II in particular, is discussed as an integral and dynamic component of the strategic debate, fundamentally affecting the nation's security policies. The implications of modern weapons technology, and the problems inherent in preserving strategic stability between adversary nations with asymmetries in military force structures and doctrines, are also discussed. Further, the study focuses on the question of whether or not nuclear superiority can be considered relevant under the contemporary international conditions

  18. Control rod drives

    International Nuclear Information System (INIS)

    Oonuki, Koji.

    1981-01-01

    Purpose: To increase the driving speed of control rods at rapid insertion with an elongate control rod and an extension pipe while ensuring sufficient buffering performance in a short buffering distance, by providing a plurality of buffers to an extension pipe between a control rod drive source and a control rod in LMFBR type reactor. Constitution: First, second and third buffers are respectively provided to an acceleration piston, an extension pipe and a control rod respectively and the insertion positions for each of the buffers are displaced orderly from above to below. Upon disconnection of energizing current for an electromagnet, the acceleration piston, the extension pipe and the control rod are rapidly inserted in one body. The first, second and third buffers are respectively actuated at each of their falling strokes upon rapid insertion respectively, and the acceleration piston, the extension pipe and the control rod receive the deceleration effect in the order correspondingly. Although the compression force is applied to the control rod only near the stroke end, it does not cause deformation. (Kawakami, Y.)

  19. Rotating magnetic field current drive-theory and experiment

    International Nuclear Information System (INIS)

    Donnelly, I.J.

    1989-01-01

    Rotating magnetic fields have been used to drive plasma current and establish a range of compact torus configurations, named rotamaks. The current drive mechanism involves a ponderomotive force acting on the electron fluid. Recent extensions of the theory indicate that this method is most suitable for driving currents in directions perpendicular to the steady magnetic fields

  20. Current Drive in a Ponderomotive Potential with Sign Reversal

    Energy Technology Data Exchange (ETDEWEB)

    N.J. Fisch; J.M. Rax; I.Y. Dodin

    2003-07-30

    Noninductive current drive can be accomplished through ponderomotive forces with high efficiency when the potential changes sign over the interaction region. The effect can practiced upon both ions and electrons. The current drive efficiencies, in principle, might be higher than those possible with conventional radio-frequency current-drive techniques, since different considerations come into play.

  1. Current Drive in a Ponderomotive Potential with Sign Reversal

    International Nuclear Information System (INIS)

    Fisch, N.J.; Rax, J.M.; Dodin, I.Y.

    2003-01-01

    Noninductive current drive can be accomplished through ponderomotive forces with high efficiency when the potential changes sign over the interaction region. The effect can practiced upon both ions and electrons. The current drive efficiencies, in principle, might be higher than those possible with conventional radio-frequency current-drive techniques, since different considerations come into play

  2. Evolution Engines and Artificial Intelligence

    Science.gov (United States)

    Hemker, Andreas; Becks, Karl-Heinz

    In the last years artificial intelligence has achieved great successes, mainly in the field of expert systems and neural networks. Nevertheless the road to truly intelligent systems is still obscured. Artificial intelligence systems with a broad range of cognitive abilities are not within sight. The limited competence of such systems (brittleness) is identified as a consequence of the top-down design process. The evolution principle of nature on the other hand shows an alternative and elegant way to build intelligent systems. We propose to take an evolution engine as the driving force for the bottom-up development of knowledge bases and for the optimization of the problem-solving process. A novel data analysis system for the high energy physics experiment DELPHI at CERN shows the practical relevance of this idea. The system is able to reconstruct the physical processes after the collision of particles by making use of the underlying standard model of elementary particle physics. The evolution engine acts as a global controller of a population of inference engines working on the reconstruction task. By implementing the system on the Connection Machine (Model CM-2) we use the full advantage of the inherent parallelization potential of the evolutionary approach.

  3. Efficient Driving of Piezoelectric Transducers Using a Biaxial Driving Technique.

    Directory of Open Access Journals (Sweden)

    Samuel Pichardo

    Full Text Available Efficient driving of piezoelectric materials is desirable when operating transducers for biomedical applications such as high intensity focused ultrasound (HIFU or ultrasound imaging. More efficient operation reduces the electric power required to produce the desired bioeffect or contrast. Our preliminary work [Cole et al. Journal of Physics: Condensed Matter. 2014;26(13:135901.] suggested that driving transducers by applying orthogonal electric fields can significantly reduce the coercivity that opposes ferroelectric switching. We present here the experimental validation of this biaxial driving technique using piezoelectric ceramics typically used in HIFU. A set of narrow-band transducers was fabricated with two sets of electrodes placed in an orthogonal configuration (following the propagation and the lateral mode. The geometry of the ceramic was chosen to have a resonance frequency similar for the propagation and the lateral mode. The average (± s.d. resonance frequency of the samples was 465.1 (± 1.5 kHz. Experiments were conducted in which each pair of electrodes was driven independently and measurements of effective acoustic power were obtained using the radiation force method. The efficiency (acoustic/electric power of the biaxial driving method was compared to the results obtained when driving the ceramic using electrodes placed only in the pole direction. Our results indicate that the biaxial method increases efficiency from 50% to 125% relative to the using a single electric field.

  4. Study of the weakly bound 26F nucleus to probe the evolution of nuclear forces near the limits of particle stability

    International Nuclear Information System (INIS)

    Lepailleur, Alexandre

    2013-01-01

    Nuclear forces play a decisive role to account for the evolution of the nuclear structure and to fix the limits of particle stability. The study of neutron-rich nuclei is particularly important to determine these limits and to reveal the disappearance or emergence of new shell gaps far from stability. We studied the weakly bound neutron-rich 26 F in order to probe the πd 5/2 xνd 3/2 interaction. Indeed this nucleus can be modeled as a closed core of 24 O on top of which a single deeply bound proton in πd 5/2 interacts with an unbound neutron in νd 3/2 . This coupling gives rise to the quadruplet of states J = 1, 2, 3, 4 of positive parity. Their determination would allow us to quantify the intensity of the πd 5/2 xνd 3/2 interaction. Among these states, the J = 1 (ground state) and J = 2 (first excited state) were already known. The search for the J = 4 state has been investigated by our group at GANIL through a β-decay experiment. The nuclei of 26 F were produced by the fragmentation of a 36 S beam and selected using the LISE spectrometer. They were then implanted in a Double Sided Stripped Silicon Detector that gave us the opportunity to achieve spatial and time correlations between the implanted ions and the products of the decays (β and γ rays). Moreover we were able to observe the delayed M3 γ transition from the isomeric J = 4 state to the J = 1 ground state and thus obtained the excitation energy of 643.4 keV for this isomeric state. We also determined several new states in 25-26 Ne that were fed by the β-decay of the ground and isomeric state of 26 F. We extracted an isomeric ratio of about 40% and adjusted the previously determined mass of 26 F according to this value, leading to ΔM = 270 (50) keV. The J = 3 state has been populated ad studied at GSI by means of a one proton knock-out reaction from a radioactive 27 Ne beam to produce the 26 F in its unbound states. When the 26 F is produced in its unbound state J = 3, it decays in 25 F + n. The

  5. Extended driving impairs nocturnal driving performances.

    Directory of Open Access Journals (Sweden)

    Patricia Sagaspe

    Full Text Available Though fatigue and sleepiness at the wheel are well-known risk factors for traffic accidents, many drivers combine extended driving and sleep deprivation. Fatigue-related accidents occur mainly at night but there is no experimental data available to determine if the duration of prior driving affects driving performance at night. Participants drove in 3 nocturnal driving sessions (3-5 am, 1-5 am and 9 pm-5 am on open highway. Fourteen young healthy men (mean age [+/-SD] = 23.4 [+/-1.7] years participated Inappropriate line crossings (ILC in the last hour of driving of each session, sleep variables, self-perceived fatigue and sleepiness were measured. Compared to the short (3-5 am driving session, the incidence rate ratio of inappropriate line crossings increased by 2.6 (95% CI, 1.1 to 6.0; P<.05 for the intermediate (1-5 am driving session and by 4.0 (CI, 1.7 to 9.4; P<.001 for the long (9 pm-5 am driving session. Compared to the reference session (9-10 pm, the incidence rate ratio of inappropriate line crossings were 6.0 (95% CI, 2.3 to 15.5; P<.001, 15.4 (CI, 4.6 to 51.5; P<.001 and 24.3 (CI, 7.4 to 79.5; P<.001, respectively, for the three different durations of driving. Self-rated fatigue and sleepiness scores were both positively correlated to driving impairment in the intermediate and long duration sessions (P<.05 and increased significantly during the nocturnal driving sessions compared to the reference session (P<.01. At night, extended driving impairs driving performances and therefore should be limited.

  6. DRIVING TURBULENCE AND TRIGGERING STAR FORMATION BY IONIZING RADIATION

    International Nuclear Information System (INIS)

    Gritschneder, Matthias; Naab, Thorsten; Walch, Stefanie; Burkert, Andreas; Heitsch, Fabian

    2009-01-01

    We present high-resolution simulations on the impact of ionizing radiation of massive O stars on the surrounding turbulent interstellar medium (ISM). The simulations are performed with the newly developed software iVINE which combines ionization with smoothed particle hydrodynamics (SPH) and gravitational forces. We show that radiation from hot stars penetrates the ISM, efficiently heats cold low-density gas and amplifies overdensities seeded by the initial turbulence. The formation of observed pillar-like structures in star-forming regions (e.g. in M16) can be explained by this scenario. At the tip of the pillars gravitational collapse can be induced, eventually leading to the formation of low-mass stars. Detailed analysis of the evolution of the turbulence spectra shows that UV radiation of O stars indeed provides an excellent mechanism to sustain and even drive turbulence in the parental molecular cloud.

  7. LAND-USE CHANGE AND ITS DRIVING FORCES OF "THREE PARALLEL RIVERS" IN NORTHWEST YUNNAN PROVINCE%滇西北三江并流区土地利用变化研究

    Institute of Scientific and Technical Information of China (English)

    王金亮; 蒋莲芳; 李瑞林

    2005-01-01

    counties that prefectures located (such as Shangri-la, Lushui and Lijiang) was faster than of that othercounties. (5) The main driving forces of LUCC of this area were social-economy factors, including population growth,science technology development, growth of economy, inheritance and development of ethnic cultures, changes of policy and laws related to resources use and environmental protection.

  8. Does positive selection drive transcription factor binding site turnover? A test with Drosophila cis-regulatory modules.

    Directory of Open Access Journals (Sweden)

    Bin Z He

    2011-04-01

    Full Text Available Transcription factor binding site(s (TFBS gain and loss (i.e., turnover is a well-documented feature of cis-regulatory module (CRM evolution, yet little attention has been paid to the evolutionary force(s driving this turnover process. The predominant view, motivated by its widespread occurrence, emphasizes the importance of compensatory mutation and genetic drift. Positive selection, in contrast, although it has been invoked in specific instances of adaptive gene expression evolution, has not been considered as a general alternative to neutral compensatory evolution. In this study we evaluate the two hypotheses by analyzing patterns of single nucleotide polymorphism in the TFBS of well-characterized CRM in two closely related Drosophila species, Drosophila melanogaster and Drosophila simulans. An important feature of the analysis is classification of TFBS mutations according to the direction of their predicted effect on binding affinity, which allows gains and losses to be evaluated independently along the two phylogenetic lineages. The observed patterns of polymorphism and divergence are not compatible with neutral evolution for either class of mutations. Instead, multiple lines of evidence are consistent with contributions of positive selection to TFBS gain and loss as well as purifying selection in its maintenance. In discussion, we propose a model to reconcile the finding of selection driving TFBS turnover with constrained CRM function over long evolutionary time.

  9. HARMONIC DRIVE SELECTION

    Directory of Open Access Journals (Sweden)

    Piotr FOLĘGA

    2014-03-01

    Full Text Available The variety of types and sizes currently in production harmonic drive is a problem in their rational choice. Properly selected harmonic drive must meet certain requirements during operation, and achieve the anticipated service life. The paper discusses the problems associated with the selection of the harmonic drive. It also presents the algorithm correct choice of harmonic drive. The main objective of this study was to develop a computer program that allows the correct choice of harmonic drive by developed algorithm.

  10. Invisible force

    International Nuclear Information System (INIS)

    Panek, Richard

    2010-01-01

    Astronomers have compiled evidence that what we always thought of as the actual universe- all the planets, stars, galaxies and matter in space -represents a mere 4% of what's out there. The rest is dark: 23% is called dark matter, 73% dark energy. Scientists have ideas about what dark matter is, but hardly any understanding about dark energy. This has led to rethinking traditional physics and cosmology. Assuming the existence of dark matter and that the law of gravitation is universal, two teams of astrophysicists, from Lawrence Berkeley National Laboratory and the Australian National University, analysed the universe's growth and to their surprise both concluded that the universe expansion is not slowing but speeding up. If the dominant force of evolution isn't gravity what is it?

  11. Brain Evolution and Human Neuropsychology: The Inferential Brain Hypothesis

    Science.gov (United States)

    Koscik, Timothy R.; Tranel, Daniel

    2013-01-01

    Collaboration between human neuropsychology and comparative neuroscience has generated invaluable contributions to our understanding of human brain evolution and function. Further cross-talk between these disciplines has the potential to continue to revolutionize these fields. Modern neuroimaging methods could be applied in a comparative context, yielding exciting new data with the potential of providing insight into brain evolution. Conversely, incorporating an evolutionary base into the theoretical perspectives from which we approach human neuropsychology could lead to novel hypotheses and testable predictions. In the spirit of these objectives, we present here a new theoretical proposal, the Inferential Brain Hypothesis, whereby the human brain is thought to be characterized by a shift from perceptual processing to inferential computation, particularly within the social realm. This shift is believed to be a driving force for the evolution of the large human cortex. PMID:22459075

  12. An Investigation of Air Force Communities of Practice: A Descriptive Study of Evolution Through Assessment of People, Process, and Technology Capabilities

    National Research Council Canada - National Science Library

    May, Jason

    2003-01-01

    ... (Gongla and Rizzuto, 2001). A primary goal of AFMC/DRW, AFMC Electronic Learning (eLearning) Knowledge Management Integrated Project Team, and the office of the Air Force Chief Information Officer is to increase CoP participation and effectiveness...

  13. Consistent Automation Solutions for Electrohydraulic Drives in Times of Industry 4.0

    OpenAIRE

    Köckemann, Albert; Birke, Benno

    2016-01-01

    Electrohydraulic drives are primarily used whenever a low power/weight ratio, a compact build and/or large forces are required for individual applications. These drives are often used together with electric drive technology in machines. However, in terms of automation, unlike electric drives, electrohydraulic drives are still largely connected via analog interfaces and centralized closed control loops today. To compensate for this competitive disadvantage of hydraulic drive technology and, at...

  14. Earth evolution as a thermal system

    Science.gov (United States)

    Tang, C.

    2014-12-01

    After fifty years of plate-tectonic theory, the reasons why earth sometime freezed as a snowball or sometime became lethally hot resulting in mass extinction remain enigmatic. This article proposes a new hypothesis on Earth evolution. The unbalance of heat between the input and output is considered as the driving force for the Earth evolution, the lithospheric expansion and associated uplift are the triggers, the self-organized progressive failure leading to collapse of the Earth are the amplifier, and the global scale response in terms of volcanism and magmatism is the globalizer. This shallow process of lithosphere may reach a critical state with a positive feedback loop, and result in the formation of no-plume original Large Igneous Provinces (NPOLIP) in a top-down pattern. Endothermic phase changes during de-compressive melting remove heat from and cool their surroundings, including the upper parts of the lithosphere. The huge loss of Earth's heat during eruption of LIPs, together with the endothermic cooling, may put the thermal cycle to an end and a new start of the cycle initiates. In summary, Earth drives itself to evolve in terms of thermal cycles. Global cooling and warming are the two stages of the many cycles during the Earth evolution. Glaciations are the extreme result of global cooling, whereas the LIPs, sometime accompanied with remarkable sea level dropping, are the extreme result of global warming, with a long recovering age, the interglacialstage, between them. They come and go as thermal cycle evolves, with climate warming, being caused by Earth itself rather than by external forces or human activities, as the most attractive prediction.

  15. A liquid helium piston pump with a superconducting drive

    International Nuclear Information System (INIS)

    Schmidt, C.

    1984-01-01

    This chapter describes a bellows pump where the driving force is achieved by an arrangement of three superconducting coils. The pump was designed for use in the supercritical helium flow circuit of the LCT-conductor test facility. The main advantage of the superconducting drive, compared to conventional pumps with external drive, is the compact design. Force transferring parts between 4.2 K and room temperature are not necessary. The pump was tested in a closed loop arrangement. The superconducting drive for a piston pump consists of a moving coil in a constant background field. Other coil configurations and the upscaling of the pump design are discussed

  16. Combination spindle-drive system for high precision machining

    Science.gov (United States)

    Gerth, Howard L.

    1977-07-26

    A combination spindle-drive is provided for fabrication of optical quality surface finishes. Both the spindle-and-drive utilize the spindle bearings for support, thereby removing the conventional drive-means bearings as a source of vibration. An airbearing spindle is modified to carry at the drive end a highly conductive cup-shaped rotor which is aligned with a stationary stator to produce torque in the cup-shaped rotor through the reaction of eddy currents induced in the rotor. This arrangement eliminates magnetic attraction forces and all force is in the form of torque on the cup-shaped rotor.

  17. Electric Vehicle - Economical driving

    DEFF Research Database (Denmark)

    Jensen, VCE, Steen V.; Schøn, Henriette

    1999-01-01

    Instruct the reader in getting most satisfaction out of an EV, especially concerning driving and loading.......Instruct the reader in getting most satisfaction out of an EV, especially concerning driving and loading....

  18. Dementia and driving

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/patientinstructions/000028.htm Dementia and driving To use the sharing features on ... please enable JavaScript. If your loved one has dementia , deciding when they can no longer drive may ...

  19. The role of meiotic drive in hybrid male sterility.

    Science.gov (United States)

    McDermott, Shannon R; Noor, Mohamed A F

    2010-04-27

    Meiotic drive causes the distortion of allelic segregation away from Mendelian expected ratios, often also reducing fecundity and favouring the evolution of drive suppressors. If different species evolve distinct drive-suppressor systems, then hybrid progeny may be sterile as a result of negative interactions of these systems' components. Although the hypothesis that meiotic drive may contribute to hybrid sterility, and thus species formation, fell out of favour early in the 1990s, recent results showing an association between drive and sterility have resurrected this previously controversial idea. Here, we review the different forms of meiotic drive and their possible roles in speciation. We discuss the recent empirical evidence for a link between drive and hybrid male sterility, also suggesting a possible mechanistic explanation for this link in the context of chromatin remodelling. Finally, we revisit the population genetics of drive that allow it to contribute to speciation.

  20. Gear bearing drive

    Science.gov (United States)

    Mavroidis, Constantinos (Inventor); Vranish, John M. (Inventor); Weinberg, Brian (Inventor)

    2011-01-01

    A gear bearing drive provides a compact mechanism that operates as an actuator providing torque and as a joint providing support. The drive includes a gear arrangement integrating an external rotor DC motor within a sun gear. Locking surfaces maintain the components of the drive in alignment and provide support for axial loads and moments. The gear bearing drive has a variety of applications, including as a joint in robotic arms and prosthetic limbs.

  1. Antihistamines and driving safety.

    Science.gov (United States)

    O'Hanlon, J F

    1988-10-27

    The results of two placebo-controlled driving performance studies confirm laboratory data showing that the nonsedating antihistamine terfenadine does not influence the driving performance of users. The amplitude of vehicle weaving calculated for drivers who received this agent did not differ from control values. Neither terfenadine nor loratadine, another nonsedating antihistamine, potentiated the adverse effects of alcohol on driving performance.

  2. Driving After a Stroke

    Science.gov (United States)

    ... 23,2015 Can I drive after a stroke? Driving is often a major concern after someone has a stroke. It’s not unusual for stroke survivors to want to drive. Being able to get around after a stroke is important. Safety behind the wheel is even more important after ...

  3. Sequential Dependencies in Driving

    Science.gov (United States)

    Doshi, Anup; Tran, Cuong; Wilder, Matthew H.; Mozer, Michael C.; Trivedi, Mohan M.

    2012-01-01

    The effect of recent experience on current behavior has been studied extensively in simple laboratory tasks. We explore the nature of sequential effects in the more naturalistic setting of automobile driving. Driving is a safety-critical task in which delayed response times may have severe consequences. Using a realistic driving simulator, we find…

  4. Simple Driving Techniques

    DEFF Research Database (Denmark)

    Rosendahl, Mads

    2002-01-01

    -like language. Our aim is to extract a simple notion of driving and show that even in this tamed form it has much of the power of more general notions of driving. Our driving technique may be used to simplify functional programs which use function composition and will often be able to remove intermediate data...

  5. Otolith shape lends support to the sensory drive hypothesis in rockfishes.

    Science.gov (United States)

    Tuset, V M; Otero-Ferrer, J L; Gómez-Zurita, J; Venerus, L A; Stransky, C; Imondi, R; Orlov, A M; Ye, Z; Santschi, L; Afanasiev, P K; Zhuang, L; Farré, M; Love, M S; Lombarte, A

    2016-10-01

    The sensory drive hypothesis proposes that environmental factors affect both signalling dynamics and the evolution of signals and receivers. Sound detection and equilibrium in marine fishes are senses dependent on the sagittae otoliths, whose morphological variability appears intrinsically linked to the environment. The aim of this study was to understand if and which environmental factors could be conditioning the evolution of this sensory structure, therefore lending support to the sensory drive hypothesis. Thus, we analysed the otolith shape of 42 rockfish species (Sebastes spp.) to test the potential associations with the phylogeny, biological (age), ecological (feeding habit and depth distribution) and biogeographical factors. The results showed strong differences in the otolith shapes of some species, noticeably influenced by ecological and biogeographical factors. Moreover, otolith shape was clearly conditioned by phylogeny, but with a strong environmental effect, cautioning about the use of this structure for the systematics of rockfishes or other marine fishes. However, our most relevant finding is that the data supported the sensory drive hypothesis as a force promoting the radiation of the genus Sebastes. This hypothesis holds that adaptive divergence in communication has significant influence relative to other life history traits. It has already been established in Sebastes for visual characters and organs; our results showed that it applies to otolith transformations as well (despite the clear influence of feeding and depth), expanding the scope of the hypothesis to other sensory structures. © 2016 European Society For Evolutionary Biology. Journal of Evolutionary Biology © 2016 European Society For Evolutionary Biology.

  6. CLIMATE CHANGE. Long-term climate forcing by atmospheric oxygen concentrations.

    Science.gov (United States)

    Poulsen, Christopher J; Tabor, Clay; White, Joseph D

    2015-06-12

    The percentage of oxygen in Earth's atmosphere varied between 10% and 35% throughout the Phanerozoic. These changes have been linked to the evolution, radiation, and size of animals but have not been considered to affect climate. We conducted simulations showing that modulation of the partial pressure of oxygen (pO2), as a result of its contribution to atmospheric mass and density, influences the optical depth of the atmosphere. Under low pO2 and a reduced-density atmosphere, shortwave scattering by air molecules and clouds is less frequent, leading to a substantial increase in surface shortwave forcing. Through feedbacks involving latent heat fluxes to the atmosphere and marine stratus clouds, surface shortwave forcing drives increases in atmospheric water vapor and global precipitation, enhances greenhouse forcing, and raises global surface temperature. Our results implicate pO2 as an important factor in climate forcing throughout geologic time. Copyright © 2015, American Association for the Advancement of Science.

  7. Sex drives intracellular conflict in yeast.

    Science.gov (United States)

    Harrison, E; MacLean, R C; Koufopanou, V; Burt, A

    2014-08-01

    Theory predicts that sex can drive the evolution of conflict within the cell. During asexual reproduction, genetic material within the cell is inherited as a single unit, selecting for cooperation both within the genome as well as between the extra-genomic elements within the cell (e.g. plasmids and endosymbionts). Under sexual reproduction, this unity is broken down as parental genomes are distributed between meiotic progeny. Genetic elements able to transmit to more than 50% of meiotic progeny have a transmission advantage over the rest of the genome and are able to spread, even where they reduce the fitness of the individual as a whole. Sexual reproduction is therefore expected to drive the evolution of selfish genetic elements (SGEs). Here, we directly test this hypothesis by studying the evolution of two independent SGEs, the 2-μm plasmid and selfish mitochondria, in populations of Saccharomyces cerevisiae. Following 22 rounds of sexual reproduction, 2-μm copy number increased by approximately 13.2 (±5.6) copies per cell, whereas in asexual populations copy number decreased by approximately 5.1 (±1.5) copies per cell. Given that the burden imposed by this parasite increases with copy number, these results support the idea that sex drives the evolution of increased SGE virulence. Moreover, we found that mitochondria that are respiratory-deficient rapidly invaded sexual but not asexual populations, demonstrating that frequent outcrossed sex can drive the de novo evolution of genetic parasites. Our study highlights the genomic perils of sex and suggests that SGEs may play a key role in driving major evolutionary transitions, such as uniparental inheritance. © 2014 The Authors. Journal of Evolutionary Biology © 2014 European Society For Evolutionary Biology.

  8. Toxin structures as evolutionary tools: Using conserved 3D folds to study the evolution of rapidly evolving peptides.

    Science.gov (United States)

    Undheim, Eivind A B; Mobli, Mehdi; King, Glenn F

    2016-06-01

    Three-dimensional (3D) structures have been used to explore the evolution of proteins for decades, yet they have rarely been utilized to study the molecular evolution of peptides. Here, we highlight areas in which 3D structures can be particularly useful for studying the molecular evolution of peptide toxins. Although we focus our discussion on animal toxins, including one of the most widespread disulfide-rich peptide folds known, the inhibitor cystine knot, our conclusions should be widely applicable to studies of the evolution of disulfide-constrained peptides. We show that conserved 3D folds can be used to identify evolutionary links and test hypotheses regarding the evolutionary origin of peptides with extremely low sequence identity; construct accurate multiple sequence alignments; and better understand the evolutionary forces that drive the molecular evolution of peptides. Also watch the video abstract. © 2016 WILEY Periodicals, Inc.

  9. Classical-driving-assisted entanglement dynamics control

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Ying-Jie, E-mail: yingjiezhang@qfnu.edu.cn [Shandong Provincial Key Laboratory of Laser Polarization and Information Technology, Department of Physics, Qufu Normal University, Qufu 273165 (China); Han, Wei [Shandong Provincial Key Laboratory of Laser Polarization and Information Technology, Department of Physics, Qufu Normal University, Qufu 273165 (China); Xia, Yun-Jie, E-mail: yjxia@qfnu.edu.cn [Shandong Provincial Key Laboratory of Laser Polarization and Information Technology, Department of Physics, Qufu Normal University, Qufu 273165 (China); Fan, Heng, E-mail: hfan@iphy.ac.cn [Beijing National Laboratory of Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing, 100190 (China); Collaborative Innovation Center of Quantum Matter, Beijing, 100190 (China)

    2017-04-15

    We propose a scheme of controlling entanglement dynamics of a quantum system by applying the external classical driving field for two atoms separately located in a single-mode photon cavity. It is shown that, with a judicious choice of the classical-driving strength and the atom–photon detuning, the effective atom–photon interaction Hamiltonian can be switched from Jaynes–Cummings model to anti-Jaynes–Cummings model. By tuning the controllable atom–photon interaction induced by the classical field, we illustrate that the evolution trajectory of the Bell-like entanglement states can be manipulated from entanglement-sudden-death to no-entanglement-sudden-death, from no-entanglement-invariant to entanglement-invariant. Furthermore, the robustness of the initial Bell-like entanglement can be improved by the classical driving field in the leaky cavities. This classical-driving-assisted architecture can be easily extensible to multi-atom quantum system for scalability.

  10. Subatomic forces

    International Nuclear Information System (INIS)

    Sutton, C.

    1989-01-01

    Inside the atom, particles interact through two forces which are never felt in the everyday world. But they may hold the key to the Universe. These ideas on subatomic forces are discussed with respect to the strong force, the electromagnetic force and the electroweak force. (author)

  11. The death drive in tourism studies

    NARCIS (Netherlands)

    Buda, Dorina Maria

    2015-01-01

    The psychoanalytical concept of the death drive postulated by Freud and Lacan refers to a constant force at the junction between life and death, which is not understood in a biological sense of physical demise of the body, nor in opposition to life. Tourist experiences in conflict zones can be more

  12. Control rod drive

    International Nuclear Information System (INIS)

    Okutani, Tetsuro.

    1988-01-01

    Purpose: To provide a simple and economical control rod drive using a control circuit requiring no pulse circuit. Constitution: Control rods in a BWR type reactor are driven by hydraulic pressure and inserted or withdrawn in the direction of applying the hydraulic pressure. The direction of the hydraulic pressure is controlled by a direction control valve. Since the driving for the control rod is extremely important in view of the operation, a self diagnosis function is disposed for rapid inspection of possible abnormality. In the present invention, two driving contacts are disposed each by one between the both ends of a solenoid valve of the direction control valve for driving the control rod and the driving power source, and diagnosis is conducted by alternately operating them. Therefore, since it is only necessary that the control circuit issues a driving instruction only to one of the two driving contacts, the pulse circuit is no more required. Further, since the control rod driving is conducted upon alignment of the two driving instructions, the reliability of the control rod drive can be improved. (Horiuchi, T.)

  13. Using driving simulators to assess driving safety.

    Science.gov (United States)

    Boyle, Linda Ng; Lee, John D

    2010-05-01

    Changes in drivers, vehicles, and roadways pose substantial challenges to the transportation safety community. Crash records and naturalistic driving data are useful for examining the influence of past or existing technology on drivers, and the associations between risk factors and crashes. However, they are limited because causation cannot be established and technology not yet installed in production vehicles cannot be assessed. Driving simulators have become an increasingly widespread tool to understand evolving and novel technologies. The ability to manipulate independent variables in a randomized, controlled setting also provides the added benefit of identifying causal links. This paper introduces a special issue on simulator-based safety studies. The special issue comprises 25 papers that demonstrate the use of driving simulators to address pressing transportation safety problems and includes topics as diverse as neurological dysfunction, work zone design, and driver distraction. Copyright (c) 2010 Elsevier Ltd. All rights reserved.

  14. Optimization of spent fuel pool weir gate driving mechanism

    Science.gov (United States)

    Liu, Chao; Du, Lin; Tao, Xinlei; Wang, Shijie; Shang, Ertao; Yu, Jianjiang

    2018-04-01

    Spent fuel pool is crucial facility for fuel storage and nuclear safety, and the spent fuel pool weir gate is the key related equipment. In order to achieve a goal of more efficient driving force transfer, loading during the opening/closing process is analyzed and an optimized calculation method for dimensions of driving mechanism is proposed. The result of optimizing example shows that the method can be applied to weir gates' design with similar driving mechanism.

  15. Current drive in a ponderomotive potential with sign reversal

    International Nuclear Information System (INIS)

    Fisch, N.J.; Dodin, I.Y.; Rax, J.M.

    2003-01-01

    Noninductive current drive can be accomplished through ponderomotive forces with high efficiency when the potential changes sign over the interaction region. The effect, which operates somewhat like a Maxwell demon, can be practiced upon both ions and electrons. The current-drive efficiencies, in principle, might be higher than those possible with conventional rf current-drive techniques. It remains, however, for us to identify how the effect might be implemented in a magnetic fusion device in a practical manner

  16. Superluminal warp drive

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez-Diaz, Pedro F. [Colina de los Chopos, Centro de Fisica ' Miguel A. Catalan' , Instituto de Matematicas y Fisica Fundamental, Consejo Superior de Investigaciones Cientificas, Serrano 121, 28006 Madrid (Spain)], E-mail: p.gonzalezdiaz@imaff.cfmac.csic.es

    2007-09-20

    In this Letter we consider a warp drive spacetime resulting from that suggested by Alcubierre when the spaceship can only travel faster than light. Restricting to the two dimensions that retains most of the physics, we derive the thermodynamic properties of the warp drive and show that the temperature of the spaceship rises up as its apparent velocity increases. We also find that the warp drive spacetime can be exhibited in a manifestly cosmological form.

  17. PMBLDC motor drive with power factor correction controller

    DEFF Research Database (Denmark)

    George, G.J.; Ramachandran, Rakesh; Arun, N.

    2012-01-01

    reliability, and low maintenance requirements. The proposed Power Factor Controller topology improves power quality by improving performance of PMBLDCM drive, such as reduction of AC main current harmonics, near unity power factor. PFC converter forces the drive to draw sinusoidal supply current in phase...

  18. Proceedings of the international conference on maglev and linear drives

    International Nuclear Information System (INIS)

    Anon.

    1986-01-01

    This book contains papers presented at a conference on Maglev and linear drives. Topics covered include: Development of superconducting magnets for the Canadian electrodynamic Maglev vehicle; Power supply system to drive HSST - Expo '86; and Thrust and levitation force characteristics of linear synchronous motors

  19. CAE DEVELOPMENT OF PRECESSIONAL DRIVES USING AUTODESK INVENTOR PLATFORM

    Directory of Open Access Journals (Sweden)

    Ion BOSTAN

    2010-06-01

    Full Text Available The paper presents the modelling and simulation of precessional drives designed in two variants capable of high transmission ratio and torque for one stage compact construction. The constructions were designed in Inventor and also as multi body systems in otionInventor. The simulations of the drives provide information concerning positions, velocities, accelerations, point trajectories, forces and moments, energies, as well as contact forces at the contact between gear teeth and satellite teeth and other data concerning the system.

  20. Medications and impaired driving.

    Science.gov (United States)

    Hetland, Amanda; Carr, David B

    2014-04-01

    To describe the association of specific medication classes with driving outcomes and provide clinical recommendations. The MEDLINE and EMBASE databases were searched for articles published from January 1973 to June 2013 on classes of medications associated with driving impairment. The search included outcome terms such as automobile driving, motor vehicle crash, driving simulator, and road tests. Only English-language articles that contained findings from observational or interventional designs with ≥ 10 participants were included in this review. Cross-sectional studies, case series, and case reports were excluded. Driving is an important task and activity for the majority of adults. Some commonly prescribed medications have been associated with driving impairment measured by road performance, driving simulation, and/or motor vehicle crashes. This review of 30 studies identified findings with barbiturates, benzodiazepines, hypnotics, antidepressants, opioid and nonsteroidal analgesics, anticonvulsants, antipsychotics, antiparkinsonian agents, skeletal muscle relaxants, antihistamines, anticholinergic medications, and hypoglycemic agents. Additional studies of medication impact on sedation, sleep latency, and psychomotor function, as well as the role of alcohol, are also discussed. Psychotropic agents and those with central nervous system side effects were associated with measures of impaired driving performance. It is difficult to determine if such associations are actually a result of medication use or the medical diagnosis itself. Regardless, clinicians should be aware of the increased risk of impaired driving with specific classes of medications, educate their patients, and/or consider safer alternatives.

  1. Universal Drive Train Facility

    Data.gov (United States)

    Federal Laboratory Consortium — This vehicle drive train research facility is capable of evaluating helicopter and ground vehicle power transmission technologies in a system level environment. The...

  2. Marine turtle mitogenome phylogenetics and evolution

    DEFF Research Database (Denmark)

    Duchene, Sebastián; Frey, Amy; Alfaro-Núñez, Luis Alonso

    2012-01-01

    The sea turtles are a group of cretaceous origin containing seven recognized living species: leatherback, hawksbill, Kemp's ridley, olive ridley, loggerhead, green, and flatback. The leatherback is the single member of the Dermochelidae family, whereas all other sea turtles belong in Cheloniidae...... distributions, shedding light on complex migration patterns and possible geographic or climatic events as driving forces of sea-turtle distribution. We have sequenced complete mitogenomes for all sea-turtle species, including samples from their geographic range extremes, and performed phylogenetic analyses...... to assess sea-turtle evolution with a large molecular dataset. We found variation in the length of the ATP8 gene and a highly variable site in ND4 near a proton translocation channel in the resulting protein. Complete mitogenomes show strong support and resolution for phylogenetic relationships among all...

  3. Low-high latitude interaction forcing on the evolution of the 400 kyr cycle in East Asian winter monsoon records during the last 2.8 Myr

    Science.gov (United States)

    Li, Dawei; Zhao, Meixun; Tian, Jun

    2017-09-01

    Variability of the East Asian winter monsoon (EAWM), stronger during glacials and weaker during interglacials, has been tightly linked to the wax and wane of the Northern Hemisphere ice sheets (NHIS) via the Siberian High over the last 2.8 million years (Myr). However, the long eccentricity cycle (ca. 400 kyr) in the EAWM record from the late Pliocene to early-Pleistocene (2.8-1.2 Ma) could not be linked to NHIS changes, which lacked the long eccentricity cycle in the Pleistocene. Here, we present the first low latitude EAWM record of the last 2.8 Myr using surface and subsurface temperature difference from the northern South China Sea to evaluate interactions between tropical ocean and EAWM changes. The results show that the EAWM variability displayed significant 400 kyr cycle between 2.8 Ma and 1.2 Ma, with weak (strong) EAWM during high (low) earth orbital eccentricity state. A super El Niño-Southern Oscillation (ENSO) proxy record, calculated using west-east equatorial Pacific sea surface temperature differences, revealed 400 kyr cycles throughout the last 2.8 Myr with warm phase during high eccentricity state. Thus, we propose that super ENSO mean state strongly modulated the EAWM strength through remote forcing to generate the 400 kyr cycle between 2.8 Ma and 1.2 Ma, while low NHIS volume was not sufficient to dominate the EAWM variation as it did over the last 0.9 Myr with 100 kyr cycles in dominance.

  4. Evolution as a molecular cooperative phenomenon

    International Nuclear Information System (INIS)

    Chela-Flores, J.

    1991-06-01

    We discuss an hypothesis according to which microscopic mechanisms due to cooperation, at the molecular level, may have been key factors in the evolution of life on Earth. We view our hypothesis as a natural extension to the molecular level of viewing cooperation (symbiosis) as an evolutionary driving force; this does not restrict the interpretation of the evolutionary process to be the result of slow accumulation of mutations in the DNA. Some evidence supporting this hypothesis is discussed: (a) The Salam enhancement factor. This molecular phenomenon was recently introduced in order to understand the bases of the first unifying principle of biochemistry, namely that transcription of all known genes in prokaryotes, protists, metazoan, and metaphytes are translated into L-amino acids, except for some bacterial membrane proteins. (b) The role that cooperative phenomena may have played in the origin of evolution itself, i.e., in the resolution of Sagan's ultraviolet paradox. (c) The relationship between evolution and the constraints imposed by embryonic development. This is considered from the point of view of molecular cooperative phenomena. (author). Refs

  5. Dual role of an ac driving force and the underlying two distinct order–disorder transitions in the vortex phase diagram of Ca{sub 3}Ir{sub 4}Sn{sub 13}

    Energy Technology Data Exchange (ETDEWEB)

    Kumar, Santosh, E-mail: santoshkumar@phy.iitb.ac.in [Department of Physics, Indian Institute of Technology Bombay, Mumbai 400076 (India); Singh, Ravi P.; Thamizhavel, A. [Department of Condensed Matter Physics and Materials Science, Tata Institute of Fundamental Research, Mumbai 400005 (India); Tomy, C.V., E-mail: tomy@phy.iitb.ac.in [Department of Physics, Indian Institute of Technology Bombay, Mumbai 400076 (India); Grover, A.K. [Department of Condensed Matter Physics and Materials Science, Tata Institute of Fundamental Research, Mumbai 400005 (India); Department of Physics, Panjab University, Chandigarh 160014 (India)

    2014-11-15

    Highlights: • This work pertains to new findings related to a broad SMP anomaly. • Broad SMP prima facie encompasses two phase transformations in vortex matter. • We demarcated two phase boundaries pertaining to order–disorder transitions which have quasi first-order nature. - Abstract: We present distinct demarcation of the Bragg glass (BG) to multi-domain vortex glass (VG) transition line and the eventual amorphization of the VG phase in a weakly pinned single crystal of the superconducting compound Ca{sub 3}Ir{sub 4}Sn{sub 13} on the basis of comprehension of the different yields about the second magnetization peak (SMP) anomaly in the dc magnetization and the corresponding anomalous feature in the ac susceptibility measurements. The shaking by a small ac magnetic field, inevitably present in the ac susceptibility measurements, is seen to result in contrasting responses in two different portions of the field-temperature (H, T) phase space of the multi-domain VG. In one of the portions, embracing the BG to VG transition across the onset of the SMP anomaly, the ac drive is surprisingly seen to assist the transformation of the well ordered BG phase to a lesser ordered VG phase. The BG phase exists as a superheated state over a small portion of the VG space and this attests to the first order nature of the BG to VG transition.

  6. Piezoelectric drive circuit

    Science.gov (United States)

    Treu, C.A. Jr.

    1999-08-31

    A piezoelectric motor drive circuit is provided which utilizes the piezoelectric elements as oscillators and a Meacham half-bridge approach to develop feedback from the motor ground circuit to produce a signal to drive amplifiers to power the motor. The circuit automatically compensates for shifts in harmonic frequency of the piezoelectric elements due to pressure and temperature changes. 7 figs.

  7. Wrong-way driving.

    NARCIS (Netherlands)

    2006-01-01

    Wrong-way driving is a phenomenon that mainly happens on motorways. Although the number of wrong-way crashes is relatively limited, their consequences are much more severe than the consequences of other motorway injury crashes. The groups most often causing wrong-way driving accidents are young,

  8. Recognizing driving in haste

    NARCIS (Netherlands)

    Rendón-Vélez, E.

    2014-01-01

    One can often hear people discussing the reasons why a road accident has happened: “She had to pick up her kids in the school before four o’clock and she was driving in haste and careless”, “He was stressed, he wanted to reach the beginning of the football match, tried to drive faster and didn't

  9. Control rod drives

    International Nuclear Information System (INIS)

    Futatsugi, Masao.

    1980-01-01

    Purpose: To secure the reactor operation safety by the provision of a fluid pressure detecting section for control rod driving fluid and a control rod interlock at the midway of the flow pass for supplying driving fluid to the control rod drives. Constitution: Between a driving line and a direction control valve are provided a pressure detecting portion, an alarm generating device, and a control rod inhibition interlock. The driving fluid from a driving fluid source is discharged by way of a pump and a manual valve into the reactor in which the control rods and reactor fuels are contained. In addition, when the direction control valve is switched and the control rods are inserted and extracted by the control rod drives, the pressure in the driving line is always detected by the pressure detection section, whereby if abnormal pressure is resulted, the alarm generating device is actuated to warn the abnormality and the control rod inhibition interlock is actuated to lock the direction control valve thereby secure the safety operation of the reactor. (Seki, T.)

  10. Switched reluctance motor drives

    Indian Academy of Sciences (India)

    Davis RM, Ray WF, Blake RJ 1981 Inverter drive for switched reluctance: circuits and component ratings. Inst. Elec. Eng. Proc. B128: 126-136. Ehsani M. 1991 Position Sensor elimination technique for the switched reluctance motor drive. US Patent No. 5,072,166. Ehsani M, Ramani K R 1993 Direct control strategies based ...

  11. Self-driving carsickness

    NARCIS (Netherlands)

    Diels, C.; Bos, J.E.

    2016-01-01

    This paper discusses the predicted increase in the occurrence and severity of motion sickness in self-driving cars. Self-driving cars have the potential to lead to significant benefits. From the driver's perspective, the direct benefits of this technology are considered increased comfort and

  12. Self-driving carsickness.

    NARCIS (Netherlands)

    Diels, C.; Bos, J.E.

    2016-01-01

    This paper discusses the predicted increase in the occurrence and severity of motion sickness in self-driving cars. Self-driving cars have the potential to lead to significant benefits. From the driver's perspective, the direct benefits of this technology are considered increased comfort and

  13. Fundamentals of electrical drives

    CERN Document Server

    Veltman, André; De Doncker, Rik W

    2007-01-01

    Provides a comprehensive introduction to various aspects of electrical drive systems. This volume provides a presentation of dynamic generic models that cover all major electrical machine types and modulation/control components of a drive as well as dynamic and steady state analysis of transformers and electrical machines.

  14. Electric Vehicle - Economical driving

    DEFF Research Database (Denmark)

    Jensen, VCE, Steen V.; Schøn, Henriette

    1999-01-01

    How do you reduce the energy-wast when driving and loading EV's - or rather: How do I get more km/l out of an EV......How do you reduce the energy-wast when driving and loading EV's - or rather: How do I get more km/l out of an EV...

  15. Driving the Landscape

    Science.gov (United States)

    Haff, P. K.

    2012-12-01

    Technological modification of the earth's surface (e.g., agriculture, urbanization) is an old story in human history, but what about the future? The future of landscape in an accelerating technological world, beyond a relatively short time horizon, lies hidden behind an impenetrable veil of complexity. Sufficiently complex dynamics generates not only the trajectory of a variable of interest (e.g., vegetation cover) but also the environment in which that variable evolves (e.g., background climate). There is no way to anticipate what variables will define that environment—the dynamics creates its own variables. We are always open to surprise by a change of conditions we thought or assumed were fixed or by the appearance of new phenomena of whose possible existence we had been unaware or thought unlikely. This is especially true under the influence of technology, where novelty is the rule. Lack of direct long-term predictability of landscape change does not, however, mean we cannot say anything about its future. The presence of persistence (finite time scales) in a system means that prediction by a calibrated numerical model should be good for a limited period of time barring bad luck or faulty implementation. Short-term prediction, despite its limitations, provides an option for dealing with the longer-term future. If a computer-controlled car tries to drive itself from New York to Los Angeles, no conceivable (or possible) stand-alone software can be constructed to predict a priori the space-time trajectory of the vehicle. Yet the drive is normally completed easily by most drivers. The trip is successfully completed because each in a series of very short (linear) steps can be "corrected" on the fly by the driver, who takes her cues from the environment to keep the car on the road and headed toward its destination. This metaphor differs in a fundamental way from the usual notion of predicting geomorphic change, because it involves a goal—to reach a desired

  16. Transmission of clonal hepatitis C virus genomes reveals the dominant but transitory role of CD8¿ T cells in early viral evolution

    DEFF Research Database (Denmark)

    Callendret, Benoît; Bukh, Jens; Eccleston, Heather B

    2011-01-01

    occurred slowly over several years of chronic infection. Together these observations indicate that during acute hepatitis C, virus evolution was driven primarily by positive selection pressure exerted by CD8(+) T cells. This influence of immune pressure on viral evolution appears to subside as chronic......The RNA genome of the hepatitis C virus (HCV) diversifies rapidly during the acute phase of infection, but the selective forces that drive this process remain poorly defined. Here we examined whether Darwinian selection pressure imposed by CD8(+) T cells is a dominant force driving early amino acid...... replacement in HCV viral populations. This question was addressed in two chimpanzees followed for 8 to 10 years after infection with a well-defined inoculum composed of a clonal genotype 1a (isolate H77C) HCV genome. Detailed characterization of CD8(+) T cell responses combined with sequencing of recovered...

  17. Control rod drives

    International Nuclear Information System (INIS)

    Nakamura, Akira.

    1984-01-01

    Purpose: To enable to monitor the coupling state between a control rod and a control rod drive. Constitution: After the completion of a control rod withdrawal, a coolant pressure is applied to a control rod drive being adjusted so as to raise only the control rod drive and, in a case where the coupling between the control rod drive and the control rod is detached, the former is elevated till it contacts the control rod and then stopped. The actual stopping position is detected by an actual position detection circuit and compared with a predetermined position stored in a predetermined position detection circuit. If both of the positions are not aligned with each other, it is judged by a judging circuit that the control rod and the control rod drives are not combined. (Sekiya, K.)

  18. Trophic specialization influences the rate of environmental niche evolution in damselfishes (Pomacentridae).

    Science.gov (United States)

    Litsios, Glenn; Pellissier, Loïc; Forest, Félix; Lexer, Christian; Pearman, Peter B; Zimmermann, Niklaus E; Salamin, Nicolas

    2012-09-22

    The rate of environmental niche evolution describes the capability of species to explore the available environmental space and is known to vary among species owing to lineage-specific factors. Trophic specialization is a main force driving species evolution and is responsible for classical examples of adaptive radiations in fishes. We investigate the effect of trophic specialization on the rate of environmental niche evolution in the damselfish, Pomacentridae, which is an important family of tropical reef fishes. First, phylogenetic niche conservatism is not detected in the family using a standard test of phylogenetic signal, and we demonstrate that the environmental niches of damselfishes that differ in trophic specialization are not equivalent while they still overlap at their mean values. Second, we estimate the relative rates of niche evolution on the phylogenetic tree and show the heterogeneity among rates of environmental niche evolution of the three trophic groups. We suggest that behavioural characteristics related to trophic specialization can constrain the evolution of the environmental niche and lead to conserved niches in specialist lineages. Our results show the extent of influence of several traits on the evolution of the environmental niche and shed new light on the evolution of damselfishes, which is a key lineage in current efforts to conserve biodiversity in coral reefs.

  19. Is a larger refuge always better? Dispersal and dose in pesticide resistance evolution.

    Science.gov (United States)

    Takahashi, Daisuke; Yamanaka, Takehiko; Sudo, Masaaki; Andow, David A

    2017-06-01

    The evolution of resistance against pesticides is an important problem of modern agriculture. The high-dose/refuge strategy, which divides the landscape into treated and nontreated (refuge) patches, has proven effective at delaying resistance evolution. However, theoretical understanding is still incomplete, especially for combinations of limited dispersal and partially recessive resistance. We reformulate a two-patch model based on the Comins model and derive a simple quadratic approximation to analyze the effects of limited dispersal, refuge size, and dominance for high efficacy treatments on the rate of evolution. When a small but substantial number of heterozygotes can survive in the treated patch, a larger refuge always reduces the rate of resistance evolution. However, when dominance is small enough, the evolutionary dynamics in the refuge population, which is indirectly driven by migrants from the treated patch, mainly describes the resistance evolution in the landscape. In this case, for small refuges, increasing the refuge size will increase the rate of resistance evolution. Our analysis distils major driving forces from the model, and can provide a framework for understanding directional selection in source-sink environments. © 2017 The Author(s). Evolution published by Wiley Periodicals, Inc. on behalf of The Society for the Study of Evolution.

  20. Manipulation of quantum evolution

    Science.gov (United States)

    Cabera, David Jose Fernandez; Mielnik, Bogdan

    1994-01-01

    The free evolution of a non-relativistic charged particle is manipulated using time-dependent magnetic fields. It is shown that the application of a programmed sequence of magnetic pulses can invert the free evolution process, forcing an arbitrary wave packet to 'go back in time' to recover its past shape. The possibility of more general operations upon the Schrodinger wave packet is discussed.

  1. Spot Feeding Spheroidal Graphite Iron with Exothermic and Insulating Ram-Up Sleeves in Vertically Parted Moulds: Efficiency, Microstructure, Dimensional Accuracy, Deformation, and Driving Force and Feeding Criteria Identification

    DEFF Research Database (Denmark)

    Vedel-Smith, Nikolaj Kjelgaard

    feeders (ram-up sleeves) is investigated, showing that this new feeding approach can be used successfully to feed secluded sections inductile cast iron (EN-GJS-500-7). The feeder efficiency is tested using a high Silicon (Si) ductile iron (EN-GJS-450-10). The limits for the examined feeder configurations......Improvement of feeder technologies for energy savings in cast iron foundries is not only the title of the project behind this dissertation; it is a good idea that can improve casting yield and reduce production cost, and in turn strengthening the foundries competitive advantage. The approach...... of solidification. The dissertation provides a new approach to feeding secluded sections, a new characterisation of the underlying feeding forces, and new knowledge about the thermal deformation effects caused and controlled by feeding....

  2. Resonant driving of a nonlinear Hamiltonian system

    International Nuclear Information System (INIS)

    Palmisano, Carlo; Gervino, Gianpiero; Balma, Massimo; Devona, Dorina; Wimberger, Sandro

    2013-01-01

    As a proof of principle, we show how a classical nonlinear Hamiltonian system can be driven resonantly over reasonably long times by appropriately shaped pulses. To keep the parameter space reasonably small, we limit ourselves to a driving force which consists of periodic pulses additionally modulated by a sinusoidal function. The main observables are the average increase of kinetic energy and of the action variable (of the non-driven system) with time. Applications of our scheme aim for driving high frequencies of a nonlinear system with a fixed modulation signal.

  3. The edge of neutral evolution in social dilemmas

    Energy Technology Data Exchange (ETDEWEB)

    Cremer, Jonas; Frey, Erwin [Arnold Sommerfeld Center for Theoretical Physics and Center for NanoScience, Department of Physics, Ludwig-Maximilians-Universitaet Muenchen, Theresienstrasse 37, D-80333 Muenchen (Germany); Reichenbach, Tobias [Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, Rockefeller University, 1230 York Avenue, New York, NY 10065 (United States)], E-mail: jonas.cremer@physik.uni-muenchen.de

    2009-09-15

    The functioning of animal as well as human societies fundamentally relies on cooperation. Yet, defection is often favorable for the selfish individual, and social dilemmas arise. Selection by individuals' fitness, usually the basic driving force of evolution, quickly eliminates cooperators. However, evolution is also governed by fluctuations that can be of greater importance than fitness differences, and can render evolution effectively neutral. Here, we investigate the effects of selection versus fluctuations in social dilemmas. By studying the mean extinction times of cooperators and defectors, a variable sensitive to fluctuations, we are able to identify and quantify an emerging 'edge of neutral evolution' that delineates regimes of neutral and Darwinian evolution. Our results reveal that cooperation is significantly maintained in the neutral regimes. In contrast, the classical predictions of evolutionary game theory, where defectors beat cooperators, are recovered in the Darwinian regimes. Our studies demonstrate that fluctuations can provide a surprisingly simple way to partly resolve social dilemmas. Our methods are generally applicable to estimate the role of random drift in evolutionary dynamics.

  4. The edge of neutral evolution in social dilemmas

    International Nuclear Information System (INIS)

    Cremer, Jonas; Frey, Erwin; Reichenbach, Tobias

    2009-01-01

    The functioning of animal as well as human societies fundamentally relies on cooperation. Yet, defection is often favorable for the selfish individual, and social dilemmas arise. Selection by individuals' fitness, usually the basic driving force of evolution, quickly eliminates cooperators. However, evolution is also governed by fluctuations that can be of greater importance than fitness differences, and can render evolution effectively neutral. Here, we investigate the effects of selection versus fluctuations in social dilemmas. By studying the mean extinction times of cooperators and defectors, a variable sensitive to fluctuations, we are able to identify and quantify an emerging 'edge of neutral evolution' that delineates regimes of neutral and Darwinian evolution. Our results reveal that cooperation is significantly maintained in the neutral regimes. In contrast, the classical predictions of evolutionary game theory, where defectors beat cooperators, are recovered in the Darwinian regimes. Our studies demonstrate that fluctuations can provide a surprisingly simple way to partly resolve social dilemmas. Our methods are generally applicable to estimate the role of random drift in evolutionary dynamics.

  5. Prebiological evolution and the metabolic origins of life.

    Science.gov (United States)

    Pratt, Andrew J

    2011-01-01

    The chemoton model of cells posits three subsystems: metabolism, compartmentalization, and information. A specific model for the prebiological evolution of a reproducing system with rudimentary versions of these three interdependent subsystems is presented. This is based on the initial emergence and reproduction of autocatalytic networks in hydrothermal microcompartments containing iron sulfide. The driving force for life was catalysis of the dissipation of the intrinsic redox gradient of the planet. The codependence of life on iron and phosphate provides chemical constraints on the ordering of prebiological evolution. The initial protometabolism was based on positive feedback loops associated with in situ carbon fixation in which the initial protometabolites modified the catalytic capacity and mobility of metal-based catalysts, especially iron-sulfur centers. A number of selection mechanisms, including catalytic efficiency and specificity, hydrolytic stability, and selective solubilization, are proposed as key determinants for autocatalytic reproduction exploited in protometabolic evolution. This evolutionary process led from autocatalytic networks within preexisting compartments to discrete, reproducing, mobile vesicular protocells with the capacity to use soluble sugar phosphates and hence the opportunity to develop nucleic acids. Fidelity of information transfer in the reproduction of these increasingly complex autocatalytic networks is a key selection pressure in prebiological evolution that eventually leads to the selection of nucleic acids as a digital information subsystem and hence the emergence of fully functional chemotons capable of Darwinian evolution.

  6. Modeling human-water-systems: towards a comprehensive and spatially distributed assessment of co-evolutions for river basins in Central Europe

    OpenAIRE

    P. Krahe; E. Nilson; M. Knoche; A.-D. Ebner von Eschenbach

    2016-01-01

    In the context of river basin and flood risk management there is a growing need to improve the understanding of and the feedbacks between the driving forces “climate and socio-economy” and water systems. We make use of a variety of data resources to illustrate interrelationships between different constituents of the human-water-systems. Taking water storage for energy production as an example we present a first analysis on the co-evolution of socio-economic and hydrological ...

  7. Electron cyclotron resonance heating and current drive

    Energy Technology Data Exchange (ETDEWEB)

    Fidone, I.; Castejon, F.

    1992-07-01

    A brief summary of the theory and experiments on electron- cyclotron heating and current drive is presented. The general relativistic formulation of wave propagation and linear absorption is considered in some detail. The O-mode and the X-mode for normal and oblique propagation are investigated and illustrated by several examples. The experimental verification of the theory in T-10 and D- III-D is briefly discussed. Quasilinear evolution of the momentum distribution and related applications as, for instance, non linear wave, damping and current drive, are also considered for special cases of wave frequencies, polarization and propagation. In the concluding section we present the general formulation of the wave damping and current drive in the absence of electron trapping for arbitrary values of the wave frequency. (Author) 13 refs.

  8. Transitionless driving on adiabatic search algorithm

    Energy Technology Data Exchange (ETDEWEB)

    Oh, Sangchul, E-mail: soh@qf.org.qa [Qatar Environment and Energy Research Institute, Qatar Foundation, Doha (Qatar); Kais, Sabre, E-mail: kais@purdue.edu [Qatar Environment and Energy Research Institute, Qatar Foundation, Doha (Qatar); Department of Chemistry, Department of Physics and Birck Nanotechnology Center, Purdue University, West Lafayette, Indiana 47907 (United States)

    2014-12-14

    We study quantum dynamics of the adiabatic search algorithm with the equivalent two-level system. Its adiabatic and non-adiabatic evolution is studied and visualized as trajectories of Bloch vectors on a Bloch sphere. We find the change in the non-adiabatic transition probability from exponential decay for the short running time to inverse-square decay in asymptotic running time. The scaling of the critical running time is expressed in terms of the Lambert W function. We derive the transitionless driving Hamiltonian for the adiabatic search algorithm, which makes a quantum state follow the adiabatic path. We demonstrate that a uniform transitionless driving Hamiltonian, approximate to the exact time-dependent driving Hamiltonian, can alter the non-adiabatic transition probability from the inverse square decay to the inverse fourth power decay with the running time. This may open up a new but simple way of speeding up adiabatic quantum dynamics.

  9. Electron - cyclotron resonance heating and current drive

    International Nuclear Information System (INIS)

    Fidone, I.; Castejon, F.

    1992-01-01

    A brief summary of the theory and experiments on electron- cyclotron heating and current drive is presented. The general relativistic formulation of wave propagation and linear absorption is considered in some detail. The O-mode and the X-mode for normal and oblique propagation are investigated and illustrated by several examples. The experimental verification of the theory in T-10 and D- III-D is briefly discussed. Quasilinear evolution of the momentum distribution and related applications as, for instance, non linear wave, damping and current drive, are also considered for special cases of wave frequencies, polarization and propagation. In the concluding section we present the general formulation of the wave damping and current drive in the absence of electron trapping for arbitrary values of the wave frequency. (Author) 13 refs

  10. Turbulent current drive mechanisms

    Science.gov (United States)

    McDevitt, Christopher J.; Tang, Xian-Zhu; Guo, Zehua

    2017-08-01

    Mechanisms through which plasma microturbulence can drive a mean electron plasma current are derived. The efficiency through which these turbulent contributions can drive deviations from neoclassical predictions of the electron current profile is computed by employing a linearized Coulomb collision operator. It is found that a non-diffusive contribution to the electron momentum flux as well as an anomalous electron-ion momentum exchange term provide the most efficient means through which turbulence can modify the mean electron current for the cases considered. Such turbulent contributions appear as an effective EMF within Ohm's law and hence provide an ideal means for driving deviations from neoclassical predictions.

  11. Fast wave current drive

    International Nuclear Information System (INIS)

    Goree, J.; Ono, M.; Colestock, P.; Horton, R.; McNeill, D.; Park, H.

    1985-07-01

    Fast wave current drive is demonstrated in the Princeton ACT-I toroidal device. The fast Alfven wave, in the range of high ion-cyclotron harmonics, produced 40 A of current from 1 kW of rf power coupled into the plasma by fast wave loop antenna. This wave excites a steady current by damping on the energetic tail of the electron distribution function in the same way as lower-hybrid current drive, except that fast wave current drive is appropriate for higher plasma densities

  12. Identifying Method of Drunk Driving Based on Driving Behavior

    Directory of Open Access Journals (Sweden)

    Xiaohua Zhao

    2011-05-01

    Full Text Available Drunk driving is one of the leading causes contributing to traffic crashes. There are numerous issues that need to be resolved with the current method of identifying drunk driving. Driving behavior, with the characteristic of real-time, was extensively researched to identify impaired driving behaviors. In this paper, the drives with BACs above 0.05% were defined as drunk driving state. A detailed comparison was made between normal driving and drunk driving. The experiment in driving simulator was designed to collect the driving performance data of the groups. According to the characteristics analysis for the effect of alcohol on driving performance, seven significant indicators were extracted and the drunk driving was identified by the Fisher Discriminant Method. The discriminant function demonstrated a high accuracy of classification. The optimal critical score to differentiate normal from drinking state was found to be 0. The evaluation result verifies the accuracy of classification method.

  13. Electromagnetic design calculation of the control rod drive mechanism

    International Nuclear Information System (INIS)

    Zhu Qirong; Zhu Jingchang

    1991-01-01

    Electromagnetic design calculation of the step-by-step magnetic jacking control rod drive mechanism includes magnetic field force calculation and design calculation of magnetomotive force for three electromagnetic iron and their coilds. The basic principle and method of electromagnetic design calculation had been expounded to take the lift magnet and lift coil for example

  14. Religious Itineraries as the Driving Forces behind Sustainable Local Development in the Veneto? Towards a Proposal for Promoting an Unusual and Often “Subliminal” Form of Heritage: Sanctuaries and Minor Churches

    Directory of Open Access Journals (Sweden)

    Luca Simone Rizzo

    2013-07-01

    Full Text Available Religious sites/assets are reacquiring pre-eminence, partly in the role of mainsprings for local development: they are privileged witnesses to collective memory and depositories for symbolic, historical, cultural and spiritual values that they have contributed towards forging. These are essential keys for interpreting “places” and their evolution, as well as for studying their various facets and nuances in greater detail. In full knowledge of this, we are presenting here a study on the subject of cultural (and religious itineraries as a determining element in territorial conservation and as an instrument for: a promoting a type of tourism that is sustainable, alternative and aware, in which the approach towards “exploitation” changes (contributing towards not only the “consumption” of experiences, but also the enrichment of the tourist; b highlighting the value of authenticity and contact with local culture, as well as promoting contextual elements that are highly distinctive. In line with the need to make better use of local religious heritage, we identified anchor sites (sanctuaries and minor churches around which to develop further forms of (religious tourism.We devised an itinerary some 300 km long that “expresses” the diverse environmental/cultural/gastronomic realities that have the sanctuaries at their centre.This itinerary and its sub-routes – created via GIS – cover the central and western parts of the Veneto, as well as the south of the Region. The main route connects the sites in an attempt to link the area under examination, thanks to a ring, to the ancient Via Romea (the subject of research and reclamation as a long distance route.

  15. Linear step drive

    International Nuclear Information System (INIS)

    Haniger, L.; Elger, R.; Kocandrle, L.; Zdebor, J.

    1986-01-01

    A linear step drive is described developed in Czechoslovak-Soviet cooperation and intended for driving WWER-1000 control rods. The functional principle is explained of the motor and the mechanical and electrical parts of the drive, power control, and the indicator of position are described. The motor has latches situated in the reactor at a distance of 3 m from magnetic armatures, it has a low structural height above the reactor cover, which suggests its suitability for seismic localities. Its magnetic circuits use counterpoles; the mechanical shocks at the completion of each step are damped using special design features. The position indicator is of a special design and evaluates motor position within ±1% of total travel. A drive diagram and the flow chart of both the control electronics and the position indicator are presented. (author) 4 figs

  16. Fundamentals of electrical drives

    NARCIS (Netherlands)

    Veltman, A.; Pulle, D.W.J.; de Doncker, R.W.

    2016-01-01

    Comprehensive, user-friendly, color illustrated introductory text for electrical drive systems that simplifies the understanding of electrical machine principles Updated edition covers innovations in machine design, power semi-conductors, digital signal processors and simulation software Presents

  17. Science of driving.

    Science.gov (United States)

    2016-08-01

    The Science of Driving project focused on developing a collaborative relationship to develop curriculum units for middle school and high school students to engage them in exciting real-world scenarios. This effort involved faculty, staff, and student...

  18. Drugs and driving

    NARCIS (Netherlands)

    Walsh, J. Michael; De Gier, Johan J.; Christopherson, Asbjørg S.; Verstraete, Alain G.

    The authors present a global overview on the issue of drugs and driving covering four major areas: (1) Epidemiology and Prevalence-which reviews epidemiological research, summarizes available information, discusses the methodological shortcomings of extant studies, and makes recommendations for

  19. Labor Force

    Science.gov (United States)

    Occupational Outlook Quarterly, 2012

    2012-01-01

    The labor force is the number of people ages 16 or older who are either working or looking for work. It does not include active-duty military personnel or the institutionalized population, such as prison inmates. Determining the size of the labor force is a way of determining how big the economy can get. The size of the labor force depends on two…

  20. Factors Driving Business Intelligence Culture

    Directory of Open Access Journals (Sweden)

    Rimvydas Skyrius

    2016-05-01

    Full Text Available The field of business intelligence (BI, despite rapid technology advances, continues to feature inadequate levels of adoption. The attention of researchers is shifting towards hu-man factors of BI adoption. The wide set of human factors influencing BI adoption con-tains elements of what we call BI culture – an overarching concept covering key managerial issues that come up in BI implementation. Research sources provide different sets of features pertaining to BI culture or related concepts – decision-making culture, analytical culture and others. The goal of this paper is to perform the review of research and practical sources to examine driving forces of BI – data-driven approaches, BI agility, maturity and acceptance – to point out culture-related issues that support BI adoption and to suggest an emerging set of factors influencing BI culture.