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Sample records for evaporated csi ki

  1. Heat enhancement of radiation resistivity of evaporated CsI, KI and KBr photocathodes

    CERN Document Server

    Tremsin, A S

    2000-01-01

    The photoemissive stability of as-deposited and heat-treated CsI, KI and KBr evaporated thin films under UV radiation is examined in this paper. After the deposition, some photocathodes were annealed for several hours at 90 deg. C in vacuum and their performance was then compared to the performance of non-heated samples. We observed that the post-evaporation thermal treatment not only increases the photoyield of CsI and KI photocathodes in the spectral range of 115-190 nm, but also reduces CsI, KI and KBr photocurrent degradation that occurs after UV irradiation. KBr evaporated layers appeared to be more radiation-resistant than CsI and KI layers. Post-deposition heat treatment did not result in any significant variation of KBr UV sensitivity.

  2. Theoretical study of the structures and electronic properties of all-surface KI and CsI nanocrystals encapsulated in single walled carbon nanotubes.

    Science.gov (United States)

    Bichoutskaia, Elena; Pyper, Nicholas C

    2008-10-21

    The structural and electronic properties of all-surface KI and CsI crystals encapsulated in single-walled carbon nanotubes are investigated theoretically with an ionic and atomistic approach using the GULP program. The short-range interactions, derived from Dirac-Fock wavefunctions, were augmented with damped dipole-dipole and dipole-quadrupole dispersive attractions. The uncorrelated interionic interactions computed using the relativistic crystal ion and relativistic integral programs accounted for anion in-crystal modifications while being exact given the ion wavefunctions. All the short-range correlation energies and the uncorrelated interactions between the ions and carbon atoms were computed using the density functional theory of a uniform electron gas of infinite extent. Unphysical self-interactions were removed by scaling the exchange interaction with a Rae factor derived from a study of the adsorption of noble gases on graphite. The predictions for the nonencapsulated crystals agreed well with those previously derived from a global analytic theory based on the Born model. This provided a good description of the contraction of the interplane distance (b) relative to the separation (R(e)) in the rocksalt structured bulk material although failing to account for the observed dilation of the intraplane ionic separations (a). Introduction of the interactions with the nanotube wall, including the ion-nanotube dispersive attractions, increased the predicted a values although these were still significantly smaller than experiment. The predicted b separations were reduced compared with those for the nonencapsulated crystals to values significantly less than observed. It is explained why introducing any ion-nanotube interactions that are sufficiently attractive as to reproduce the experimental a values must significantly underestimate the b separations. The partial transfer of anion electrons to the nanotube carbon atoms, not considered hitherto, was described by

  3. Evaporators

    DEFF Research Database (Denmark)

    Knudsen, Hans Jørgen Høgaard

    1996-01-01

    Type of evaporators. Regulation. Thermal dimensioning. Determination of pressure loss and heat transfer coefficients.......Type of evaporators. Regulation. Thermal dimensioning. Determination of pressure loss and heat transfer coefficients....

  4. CSI cardiac prevent 2015

    Directory of Open Access Journals (Sweden)

    S Ramakrishnan

    2015-01-01

    Full Text Available The CSI Cardiac Prevent 2015 was held at Hotel Taj Palace, New Delhi, on September 25-27, 2015. The major challenge was to create interest among cardiologists and physicians on preventive cardiology, a neglected area. The theme of the conference was "Innovations in Heart Disease Prevention.′′ This conference included "CSI at WHF Roadmap Workshop, Inauguration Ceremony, scientific program, plenary sessions, Nursing/Dietician track, Industry Exhibition, Social Events," Great India blood pressure Survey, and CSI Smart Heart App. A total of 848 delegates/faculties attended this conference against a total of 1140 people registered for the meeting.

  5. Csi-star: a Low-cost CSI Orbital Testbed

    Science.gov (United States)

    Edberg, D.

    1992-01-01

    The topics are presented in viewgraph form and include the following: rationale for an on-orbit control-structurs interaction (CSI) test facility; CSI flight experiment objectives; feasibility study objectives; CSI free-flyer solution; feasibility study technical status summary; CSI-Star - a low-cost CSI free flyer; conceptual experiment design - option 2 configuration; Delta 2 - Quickstar Interface clambband capability; open and closed loop response of baselined truss with active struts; experiment weight baseline (option 1) configuration; experiment weight option 2 configuration; experiment power baseline (option 1) configuration; experiment power option 2 configuration; CSI Quickstar capabilities/requirements; and remaining work.

  6. The CSI Schools Project

    Science.gov (United States)

    Dorling, Mark; Johnstone, Emm

    2012-01-01

    The popularity of forensic science in schools continues to grow alongside the proportion of prime time scheduling devoted to CSI television shows. Yet the understanding of how forensic tests are used in narrowing down a field of possible suspects to the point where just one can be arrested or taken to trial is far less well understood. Students…

  7. Enhanced quantum efficiency for CsI grown on a graphite-based substrate coating

    CERN Document Server

    Friese, J; Homolka, J; Kastenmüller, A; Maier-Komor, P; Peter, M; Zeitelhack, K; Kienle, P; Körner, H J

    1999-01-01

    Quantum efficiencies (QE) in the vacuum ultraviolet (VUV) wavelength region have been measured for solid CsI layers on various substrates. The CsI films were deposited applying electron beam evaporation. The QE measurements were performed utilizing synchrotron radiation as well as light from a deuterium lamp. A GaAsP diode with a sensitivity calibration traceable to a primary radiation standard was used for normalization. For CsI layers grown on resin-stabilized graphite films a significant enhancement of QE was observed. Substrates suitable for gas detector applications and aging properties were investigated. The procedures to prepare and reproduce high quantum efficient CsI layers are described.

  8. Quantum efficiency measurement system for large area CsI photodetectors

    CERN Document Server

    Cusanno, F; Colilli, S; Crateri, R; Fratoni, R; Frullani, S; Garibaldi, F; Giuliani, F; Gricia, M; Lucentini, M; Mostarda, A; Santavenere, F; Veneroni, P; Breuer, H; Iodice, M; Urciuoli, G M; De Cataldo, G; De Leo, R; Lagamba, L; Braem, André

    2003-01-01

    A proximity focusing freon/CsI RICH detector has been built for kaon physics at Thomas Jefferson National Accelerator Facility (TJNAF or Jefferson Lab), Hall A. The Cherenkov photons are detected by a UV photosensitive CsI film which has been obtained by vacuum evaporation. A dedicated evaporation facility for large area photocathodes has been built for this task. A measuring system has been built to allow the evaluation of the absolute quantum efficiency (QE) just after the evaporation. The evaporation facility is described here, as well as the quantum efficiency measurement device. Results of the QE on-line measurements, for the first time on large area photocathodes, are reported.

  9. Ki-Young choi

    Indian Academy of Sciences (India)

    2015-11-27

    Nov 27, 2015 ... Home; Journals; Pramana – Journal of Physics. Ki-Young choi. Articles written in Pramana – Journal of Physics. Volume 86 Issue 1 January 2016 pp 169-183. Quasar polarization with ultralight (pseudo-)scalars · Ki-Young choi Subhayan Mandal Chang Sub Shin · More Details Abstract Fulltext PDF.

  10. CSI Effect of Crime Clarification

    Directory of Open Access Journals (Sweden)

    Aylin Yakupoğlu

    2016-08-01

    Full Text Available Objective: This research is aimed to evaluate the impact of CSI series on Criminal Justice Professional’s attitudes and behaviour and how these programs effecting public. From this point of view criminal justice professionals are expected to respond questions about, how this kind of dramas and programs guided potential criminals, reflected the practice of forensic science and directed the public expectation regarding performing their professions. Material and Methods: A survey has been conducted to 266 participants, who are working as crime scene investigation specialists, criminal courts judges, public prosecutors, lawyers, law enforcement personnel and forensic specialists, to reveal their perceptions. Gained data has been analyzed statistically by using SPSS (Version 20.0. Findings: According to some results of the research; 1 out of every 2 participants are following CSI series. only 3 out of every 10 participants expressed that these kind of series have positive effects on their professional practices, more than half of the participants agreed that crime dramas are effecting criminal behaviour and creating trained perpetrators. Also 1 out of every 2 participants believe that the perpetrators are attentive to leave fewer evidence because of these programs. Results: CSI series are not reflecting forensic techniques and methods as what it’s supposed to be in real life. Due to the raise of public interest in forensic sciences because of these dramas people changed their expectation about criminal justice mechanism which can be cause misperceptions on citizens who face with investigation and prosecution processes for the first time Keywords: CSI Effect; Crime Scene Investigation; Forensic Techniques and Methods

  11. CSI: Immigrant Children--Clues for Teacher Education

    Science.gov (United States)

    Larke, Patricia J.

    2012-01-01

    The metaphor of the popular television shows "CSI: New York," "CSI: Miami," and "CSI: Las Vegas" (CSI stands for "crime scene investigation") is applicable to investigating issues of immigrant children in teacher preparation programs (TPP). One of the fundamental principles of CSI is to solve the crime by…

  12. Interference Alignment with Partial CSI Feedback in MIMO Cellular Networks

    OpenAIRE

    Rao, Xiongbin; Lau, Vincent K. N.

    2014-01-01

    Interference alignment (IA) is a linear precoding strategy that can achieve optimal capacity scaling at high SNR in interference networks. However, most existing IA designs require full channel state information (CSI) at the transmitters, which would lead to significant CSI signaling overhead. There are two techniques, namely CSI quantization and CSI feedback filtering, to reduce the CSI feedback overhead. In this paper, we consider IA processing with CSI feedback filtering in MIMO cellular n...

  13. Improved reconstruction for IDEAL spiral CSI

    DEFF Research Database (Denmark)

    Hansen, Rie Beck; Mariager, Christian; Laustsen, Christoffer

    In this study we demonstrate how reconstruction for IDEAL spiral CSI (spectroscopic imaging scheme developed for hyperpolarized dynamic metabolic MR imaging) can be improved by using regularization with a sparsity constraint. By exploiting sparsity of the spectral domain, IDEAL spiral CSI can...

  14. Improved reconstruction for IDEAL spiral CSI

    DEFF Research Database (Denmark)

    Hansen, Rie Beck; Mariager, Christian; Laustsen, Christoffer

    2017-01-01

    In this study we demonstrate how reconstruction for IDEAL spiral CSI (spectroscopic imaging scheme developed for hyperpolarized dynamic metabolic MR imaging) can be improved by using regularization with a sparsity constraint. By exploiting sparsity of the spectral domain, IDEAL spiral CSI can...

  15. KiWi Vision

    DEFF Research Database (Denmark)

    Schaffert, Sebastian; Bry, Francois; Dolog, Peter

    This deliverable describes the common vision of the KiWi project, ranging from motivation over use cases and usage scenarios to user interaction, system architecture and technologies, and the research that is performed as part of the project. The deliverable is intended for a wide audience to give...

  16. Flexible Computer Science Infrastructure (FleCSI)

    Energy Technology Data Exchange (ETDEWEB)

    2016-04-06

    FleCSI is a compile-time configurable framework designed to support multi-physics application development. As such, FleCSI attempts to provide a very general set of infrastructure design patterns that can be specialized and extended to suit the needs of a broad variety of solver and data requirements. Current support includes multi-dimensional mesh topology, mesh geometry, and mesh adjacency information, n-dimensional hashed-tree data structures, graph partitioning interfaces, and dependency closures. FleCSI also introduces a functional programming model with control, execution, and data abstractions that are consistent with both MPI and state-of-the-art task-based runtimes such as Legion and Charm++. The FleCSI abstraction layer provides the developer with insulation from the underlying runtime, while allowing support for multiple runtime systems, including conventional models like asynchronous MPI. The intent is to give developers a concrete set of user-friendly programming tools that can be used now, while allowing flexibility in choosing runtime implementations and optimizations that can be applied to architectures and runtimes that arise in the future. The control and execution models in FleCSI also provide formal nomenclature for describing poorly understood concepts like kernels and tasks.

  17. Based on the CSI regional segmentation indoor localization algorithm

    Science.gov (United States)

    Zeng, Xi; Lin, Wei; Lan, Jingwei

    2017-08-01

    To solve the problem of high cost and low accuracy, the method of Channel State Information (CSI) regional segmentation are proposed in the indoor positioning. Because Channel State Information (CSI) stability, and effective against multipath effect, we used the Channel State Information (CSI) to segment location area. The method Acquisition CSI the influence of different link to pinpoint the location of the area. Then the method can improve the accuracy of positioning, and reduce the cost of the fingerprint localization algorithm.

  18. CSI: An Engaging Online Classroom Introduction Activity

    Science.gov (United States)

    Stephens, Geralyn E.

    2015-01-01

    All course activities should be aimed at moving students towards the learning outcomes, including class introductions. This article provides detailed instructions for implementing an online Class Session Introductions (CSI) activity that immediately engages students with their peers, the content and the instructor. The activity may be useful to…

  19. AACN CSI Academy, part 3: Introducing the Massachusetts CSI Nursing Delirium Collaborative.

    Science.gov (United States)

    DiLibero, Justin; Edwards, Erica; Hanson, Dave

    2015-11-01

    In the final installment of our three-part series, we reveal how the Boston cohort of the American Association of Critical-Care Nurses (AACN) Clinical Scene Investigator (CSI) Academy launched a collective to improve patient safety and quality outcomes related to delirium.

  20. Preparation and calibration of CsI photocathode and its x-ray imaging performance for high power laser interaction with Au foams at SGIII facility

    Science.gov (United States)

    Li, Yukun; Fan, Long; Chen, Tao; Deng, Bo; Li, Jin; Deng, Keli; Hu, Xin

    2017-05-01

    We used a 300nm polycarbonate (PC) membrane as a supported structure and CsI photocathode was evaporated onto PC surface. The thickness of CsI can be controlled between 100 nm to 1 μm. The effects of deposition speed and deliquescence property on morphology and structure were analyzed. The photoelectric conversion properties of CsI films were analyzed with Manson X-ray source. The energy spectral response peak value of photocathode is above 3000μA/W calibrated at Beijing synchrotron radiation facility. The photocathode was applied to an X-ray streak camera on SG III facility and distinct x-ray images were captured.

  1. CSI Lawyer® Windows Phone® Client Development and Data Synchronization

    OpenAIRE

    Sedha, Arvind

    2012-01-01

    CSI Helsinki Oy has ERP software called CSI Lawyer® which is intended for law and consultant companies. CSI Helsinki Oy has great demand to develop the mobile clients for CSI Lawyer® for the most common mobile platforms available at present. The purpose of this project was to develop the Windows Phone® client application called CSI Mobile® for CSI Lawyer® including backend data synchronization business logic. CSI Mobile® allows CSI Lawyer® users to manage their transactions and view tran...

  2. Philosophy, Psychology, Physics and Practice of Ki

    Science.gov (United States)

    Ohnishi, Tomoko

    2009-01-01

    Ki (in Japanese) or Qi (in Chinese) is the key concept in Eastern medicine, Eastern philosophy, as well as in martial arts. We explain the philosophical and psychological background of Ki. We emphasize that the unique aspects of Eastern philosophy are ‘non-linearity’ and ‘holistic’ approach. We then present physics aspect of Ki. Our experiments demonstrated that a ‘Ki-beam’ carries ‘entropy’ (or information), which is different from ‘energy’. We introduce our experience of having taught Ki to 37 beginners in the United States through the Nishino Breathing Method. If beginners had martial arts training or a strong background in music or dance, about half of them could sense Ki within 10 weeks (1 h class per week) of practice. PMID:18955316

  3. Philosophy, Psychology, Physics and Practice of Ki

    Directory of Open Access Journals (Sweden)

    S. Tsuyoshi Ohnishi

    2009-01-01

    Full Text Available Ki (in Japanese or Qi (in Chinese is the key concept in Eastern medicine, Eastern philosophy, as well as in martial arts. We explain the philosophical and psychological background of Ki. We emphasize that the unique aspects of Eastern philosophy are ‘non-linearity’ and ‘holistic’ approach. We then present physics aspect of Ki. Our experiments demonstrated that a ‘Ki-beam’ carries ‘entropy’ (or information, which is different from ‘energy’. We introduce our experience of having taught Ki to 37 beginners in the United States through the Nishino Breathing Method. If beginners had martial arts training or a strong background in music or dance, about half of them could sense Ki within 10 weeks (1 h class per week of practice.

  4. MIMO channel capacity with full CSI at Low SNR

    KAUST Repository

    Tall, Abdoulaye

    2012-10-01

    In this paper, we characterize the ergodic capacity of Multiple Input Multiple Output (MIMO) Rayleigh fading channels with full channel state information (CSI) at both the transmitter (CSI-T) and the receiver (CSI-R) at asymptotically low signal-to-noise ratio (SNR). A simple analytical expression of the capacity is derived for any number of transmit and receive antennas. This characterization clearly shows the substantial gain in terms of capacity over the no CSI-T case and gives a good insight on the effect of the number of antennas used. In addition, an On-Off transmission scheme is proposed and is shown to be asymptotically capacity-achieving. © 2012 IEEE.

  5. AACN CSI Academy, part 2: Nurses emerge as change leaders.

    Science.gov (United States)

    Iacono, Laura; Altman, Marian

    2015-08-01

    In the first part of this three-part series, we explored how the American Association of Critical-Care Nurses (AACN) Clinical Scene Investigator (CSI) Academy aids clinical nurses in cultivating skills that measurably demonstrate how nonproductive time is a misnomer that interferes with achieving optimal patient outcomes. Join us for part 2, as we examine how the CSI Academy helped one hospital's neurosurgical ICU (NSCU) nurses achieve zero CAUTIs.

  6. The CSI effect and the Canadian and the Australian Jury.

    Science.gov (United States)

    Holmgren, Janne A; Fordham, Judith

    2011-01-01

    Television shows, such as CBS's CSI and its spin-offs CSI: Miami; CSI: Las Vegas; and CSI: New York, have sparked the imagination of thousands of viewers who want to become forensic scientists. The shows' fictional portrayals of crime scene investigations have prompted fears that jurors will demand DNA and other forensic evidence before they will convict, and have unrealistic expectations of that evidence. This has been dubbed the "CSI effect." This phenomenon was explored using results from a Canadian study based on 605 surveys of Canadian college students who would be considered jury-eligible and Australian quantitative and qualitative findings from a study that surveyed and interviewed real posttrial jurors. Information about the way jurors deal with forensic evidence in the context of other evidence and feedback about the way in which understanding such evidence could be increased were gained from both these studies. The comparison provides insights into the knowledge base of jurors, permitting adaptation of methods of presenting forensic information by lawyers and experts in court, based on evidence rather than folklore. While the Canadian juror data showed statistically significant findings that jurors are clearly influenced in their treatment of some forensic evidence by their television-viewing habits, reassuringly, no support was found in either study for the operation of a detrimental CSI effect as defined above. In the Australian study, in fact, support was found for the proposition that jurors assess forensic evidence in a balanced and thoughtful manner. © 2010 American Academy of Forensic Sciences.

  7. Children's Somatization Inventory: psychometric properties of the revised form (CSI-24).

    Science.gov (United States)

    Walker, Lynn S; Beck, Joy E; Garber, Judy; Lambert, Warren

    2009-05-01

    To conduct a multimethod psychometric evaluation to refine the Children's Somatization Inventory (CSI) and to investigate its dimensionality. The CSI was administered to 876 pediatric patients with chronic abdominal pain at their initial visit to a pediatric gastroenterology clinic. Tools from three psychometric models identified items that most effectively measured the construct of somatization and examined its dimensionality. Eleven statistically weak items were identified and removed, creating a 24-item CSI (CSI-24). The CSI-24 showed good psychometrics according to the three measurement models and correlated .99 with the original CSI. The CSI-24 has one dominant general factor but is not strictly unidimensional. The CSI-24 is a reliable and psychometrically sound refinement of the original CSI. Findings are consistent with the view that somatization has a strong general factor that represents a continuum of symptom reporting, as well as minor components that represent specific symptom clusters in youth with chronic abdominal pain.

  8. Preliminary validation of the Claudication Symptom Instrument (CSI).

    Science.gov (United States)

    Edwards, Todd C; Lavallee, Danielle C; Clowes, Alexander W; Devine, Emily B; Flum, David R; Meissner, Mark H; Thomason, Ellen T; Barbic, Skye P; Beck, Sara J; Patrick, Donald L

    2017-09-01

    This article describes the development of the Claudication Symptom Instrument (CSI) and its measurement properties for evaluating the symptom experience of patients diagnosed with intermittent claudication (IC). We conducted semi-structured qualitative interviews with IC patients for item development and cognitive interviews in which patient comprehension of items was tested. We evaluated measurement properties using data collected and analyzed in the context of an observational comparative effectiveness study of IC treatments. Items measuring five symptom important to patients were developed and cognitively tested: Pain, Numbness, Heaviness, Cramping, and Tingling. Item means (higher means worse) ranged from 1.1 (Tingling) to 2.3 (Pain) (range: 0 'none' to 4 'extreme'). Rasch analysis yielded support for an overall score (χ(2)=26.5, df=20, p=0.15). The total CSI score differed by clinician-rated severity of mild versus moderate ( pCSI 5-10 days after baseline yielded an intra-class correlation coefficient of 0.86. Changes in CSI total score and VASCUQOL total score between baseline and 6 months post-treatment were correlated at -0.52 ( pCSI preliminarily meets accepted measurement standards for content validity, internal consistency and test-retest reliability, construct validity, and sensitivity for detecting change. Because of its high test-retest reliability, it may also be useful in clinical care with individual patients. It takes approximately 3 minutes to complete.

  9. Spatial Intercell Interference Cancellation with CSI Training and Feedback

    CERN Document Server

    Zhang, Jun; Letaief, Khaled B

    2011-01-01

    We investigate intercell interference cancellation (ICIC) with a practical downlink training and uplink channel state information (CSI) feedback model. The average downlink throughput for such a 2-cell network is derived. The user location has a strong effect on the signal-to-interference ratio (SIR) and the channel estimation error. This motivates adaptively switching between traditional (single-cell) beamforming and ICIC at low signal-to-noise ratio (SNR) where ICIC is preferred only with low SIR and accurate channel estimation, and the use of ICIC with optimized training and feedback at high SNR. For a given channel coherence time and fixed training and feedback overheads, we develop optimal data vs. pilot power allocation for CSI training as well as optimal feedback resource allocation to feed back CSI of different channels. Both analog and finite-rate digital feedback are considered. With analog feedback, the training power optimization provides a more significant performance gain than feedback optimizat...

  10. Logistički informacioni sistem

    OpenAIRE

    Andrejić D. Marko; Milenkov A. Marjan; Sokolović S. Vlada

    2010-01-01

    Logistički automatizovani informacioni sistem treba razvijati kao deo jedinstvenog automatizovanog informacionog sistema (JAIS-a). Da bi se logistički automatizovani informacioni sistem uspešno razvijao i primenjivao u operativnoj praksi, neophodno je slediti globalni koncept razvoja JAIS-a i u razvoju više primenjivati timski rad profesionalnog informatičara i poznavaoca realnog logističkog sistema. Bitan uslov za razvoj kvalitetnog logističkog informacionog sistema jeste d...

  11. Ekološki terorizem : magistrsko delo

    OpenAIRE

    Domjanič, Mario

    2013-01-01

    Skozi analizo strokovne literature in intervjujev, opravljenih s slovenskimi strokovnjaki s področja ekologije, okoljske kriminalitete in terorizma, skušamo v magistrski nalogi predstaviti problematiko pojma ekološki terorizem, v nadaljevanju eko terorizem. Podobno kot pri pojmu terorizem se tudi pri eko terorizmu soočimo z velikim številom definicij, ki eko terorizem opredeljujejo v treh oblikah, in sicer kot izraba okolja za teroriziranje, kot teroriziranje okolja ter kot taktiko radikalnih...

  12. Reproducibility of rapid short echo time CSI at 3 tesla for clinical applications

    National Research Council Canada - National Science Library

    Van Cauter, Sofie; Sima, Diana M; Luts, Jan; ter Beek, Leon; Ribbens, Annemie; Peeters, Ronald R; Osorio Garcia, Maria I; Li, Yuquan; Sunaert, Stefan; Van Gool, Stefaan W; Van Huffel, Sabine; Himmelreich, Uwe

    2013-01-01

    .... Ten volunteers were imaged three times on two different 3 Tesla (T) MRI scanners, receiving anatomical imaging and two identical CSI measurements, using automated repositioning software for consistent repositioning of the CSI grid...

  13. Ameriški najstniški svet v specifiki podnaslavljanja filma Juno

    OpenAIRE

    Orešnik, Veronika

    2009-01-01

    Film Juno, ki ga odlikujejo pikantni in zabavni dialogi, popelje slovenskega gledalca v ameriški najstniški svet. Film je kot najstniški upornik: drugačen, nemoralističen, obravnava številne najstniške probleme, vsebuje obilico slenga in humorja – sleherni delček filma je vzet iz najstniškega sveta. Prevajalec se mora zato potopiti v ta svet, da lahko razvozla prevajalske neznanke, prepletene s kulturnimi in jezikovnimi preprekami kot tudi z omejitvami podnaslavljanja. V diplomskem delu sem n...

  14. Evaporation From Lake Superior

    Science.gov (United States)

    Spence, C.; Blanken, P.; Hedstrom, N.; Leshkevich, G.; Fortin, V.; Charpentier, D.; Haywood, H.

    2009-05-01

    Evaporation is a critical component of the water balance of each of the Laurentian Great Lakes, and understanding the magnitude and physical controls of evaporative water losses are important for several reasons. Recently, low water levels in Lakes Superior and Michigan/Huron have had socioeconomic, ecological, and even meteorological impacts (e.g. water quality and quantity, transportation, invasive species, recreation, etc.). The recent low water levels may be due to increased evaporation, but this is not known as operational evaporation estimates are currently calculated as the residual of water or heat budgets. Perhaps surprisingly, almost nothing is known about evaporation dynamics from Lake Superior and few direct measurements of evaporation have been made from any of the Laurentian Great Lakes. This research is the first to attempt to directly measure evaporation from Lake Superior by deploying eddy covariance instrumentation. Results of evaporation rates, their patterns and controlling mechanisms will be presented. The direct measurements of evaporation are used with concurrent satellite and climate model data to extrapolate evaporation measurements across the entire lake. This knowledge could improve predictions of how climate change may impact the lake's water budget and subsequently how the water in the lake is managed.

  15. Uplink Contention-based CSI Feedback with Prioritized Layers for a Multi-Carrier System

    DEFF Research Database (Denmark)

    Kaneko, Megumi; Hayashi, Kazunori; Popovski, Petar

    2012-01-01

    performance analysis of the proposed scheme, assuming Maximum CSI (Max CSI) and normalized Proportional Fair Scheduler (PFS), where a tight approximation of the achievable throughput is obtained assuming discrete Adaptive Modulation (AM) and CSI feedback which are relevant for the practical systems....... Analytical and simulation results show that our proposed scheme provides an excellent trade-off between system performance and feedback overhead....

  16. CSI related dynamics and control issues in space robotics

    Science.gov (United States)

    Schmitz, Eric; Ramey, Madison

    1993-01-01

    The research addressed includes: (1) CSI issues in space robotics; (2) control of elastic payloads, which includes 1-DOF example, and 3-DOF harmonic drive arm with elastic beam; and (3) control of large space arms with elastic links, which includes testbed description, modeling, and experimental implementation of colocated PD and end-point tip position controllers.

  17. Evaporation and Antievaporation instabilities

    OpenAIRE

    Addazi, Andrea; Marciano, Antonino

    2017-01-01

    We review (anti)evaporation phenomena within the context of quantum gravity and extended theories of gravity. The (anti)evaporation effect is an instability of the black hole horizon discovered in many different scenarios: quantum dilaton-gravity, $f(R)$-gravity, $f(T)$-gravity, string inspired black holes and brane-world cosmology. Evaporating and antievaporating black holes seem to have completely different thermodynamical features compared to standard semiclassical black holes. The purpose...

  18. Development of the CsI Calorimeter Subsystem for AMEGO

    Science.gov (United States)

    Grove, J. Eric; Woolf, Richard; Johnson, W. Neil; Phlips, Bernard

    2018-01-01

    We report on the development of the thallium-doped cesium iodide (CsI:Tl) calorimeter subsystem for the All-Sky Medium-Energy Gamma-ray Observatory (AMEGO). The CsI calorimeter is one of the three main subsystems that comprise the AMEGO instrument suite; the others include the double-sided silicon strip detector (DSSD) tracker/converter and a cadmium zinc telluride (CZT) calorimeter. Similar to the LAT instrument on Fermi, the hodoscopic calorimeter consists of orthogonally layered CsI bars. Unlike the LAT, which uses PIN photodiodes, the scintillation light readout from each end of the CsI bar is done with recently developed large-area silicon photomultiplier (SiPM) arrays. We currently have an APRA program to develop the calorimeter technology for a larger, future space-based gamma-ray observatory. Under this program, we are building and testing a prototype calorimeter consisting of 24 CsI bars (16.7 mm x 16.7 mm x 100 mm) arranged in 4 layers with 6 bars per layer. The ends of each bar are read out with a 2 x 2 array of 6 mm x 6 mm SensL J series SiPMs. Signal readout and processing is done with the IDEAS SIPHRA (IDE3380) ASIC. Performance testing of this prototype will be done with laboratory sources, a beam test, and a balloon flight in conjunction with the other subsystems led by NASA GSFC. Additionally, we will test 16.7 mm x 16.7 mm x 450 mm CsI bars with SiPM readout to understand the performance of longer bars in advance of the developing the full instrument.Acknowledgement: This work was sponsored by the Chief of Naval Research (CNR) and NASA-APRA (NNH15ZDA001N-APRA).

  19. ATDM LANL FleCSI: Topology and Execution Framework

    Energy Technology Data Exchange (ETDEWEB)

    Bergen, Benjamin Karl [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-11-06

    FleCSI is a compile-time configurable C++ framework designed to support multi-physics application development. As such, FleCSI attempts to provide a very general set of infrastructure design patterns that can be specialized and extended to suit the needs of a broad variety of solver and data requirements. This means that FleCSI is potentially useful to many different ECP projects. Current support includes multidimensional mesh topology, mesh geometry, and mesh adjacency information, n-dimensional hashed-tree data structures, graph partitioning interfaces, and dependency closures (to identify data dependencies between distributed-memory address spaces). FleCSI introduces a functional programming model with control, execution, and data abstractions that are consistent with state-of-the-art task-based runtimes such as Legion and Charm++. The model also provides support for fine-grained, data-parallel execution with backend support for runtimes such as OpenMP and C++17. The FleCSI abstraction layer provides the developer with insulation from the underlying runtimes, while allowing support for multiple runtime systems, including conventional models like asynchronous MPI. The intent is to give developers a concrete set of user-friendly programming tools that can be used now, while allowing flexibility in choosing runtime implementations and optimizations that can be applied to architectures and runtimes that arise in the future. This project is essential to the ECP Ristra Next-Generation Code project, part of ASC ATDM, because it provides a hierarchically parallel programming model that is consistent with the design of modern system architectures, but which allows for the straightforward expression of algorithmic parallelism in a portably performant manner.

  20. Personalization Component for KiWi Framework

    DEFF Research Database (Denmark)

    Durao, Frederico; Xu, Guandong; Kotowski, Jakub

    2010-01-01

    . The personalization component is responsible for addressing and delivering information to individuals regarding their roles and preferences, explicitly or implicitly inferred from their activities in the system. Personalization is a essential for KiWi since this in a multi-user environment and individuals has......In this report we present the personalization component implemented for KiWi addressing diverse aspects such as motivation scenarios, configuration management, formal models, implementations and some real case scenarios on how personalization can be applied to support software project management...... different interests and needs when using the system....

  1. Measure Guideline: Evaporative Condensers

    Energy Technology Data Exchange (ETDEWEB)

    German, A [Alliance for Residential Building Innovation (ARBI), Davis, CA (United States); Dakin, B. [Alliance for Residential Building Innovation (ARBI), Davis, CA (United States); Hoeschele, M. [Alliance for Residential Building Innovation (ARBI), Davis, CA (United States)

    2012-03-01

    This measure guideline on evaporative condensers provides information on properly designing, installing, and maintaining evaporative condenser systems as well as understanding the benefits, costs, and tradeoffs. This is a prescriptive approach that outlines selection criteria, design and installation procedures, and operation and maintenance best practices.

  2. Kaurismäki Soome parim

    Index Scriptorium Estoniae

    2007-01-01

    Soome filmiauhinna Jussi võitis A. Kaurismäki "Äärelinna tuled" ("Laitakaupungin valot"), viis Jussit sai Aku Louhimiehe film "Jäine linn" ("Valkoinen kaupunki") ja kaks Jussit Eesti osalusega "Igavese armastuse sõdalane - Jade Warrior"

  3. CSI Flight Computer System and experimental test results

    Science.gov (United States)

    Sparks, Dean W., Jr.; Peri, F., Jr.; Schuler, P.

    1993-01-01

    This paper describes the CSI Computer System (CCS) and the experimental tests performed to validate its functionality. This system is comprised of two major components: the space flight qualified Excitation and Damping Subsystem (EDS) which performs controls calculations; and the Remote Interface Unit (RIU) which is used for data acquisition, transmission, and filtering. The flight-like RIU is the interface between the EDS and the sensors and actuators positioned on the particular structure under control. The EDS and RIU communicate over the MIL-STD-1553B, a space flight qualified bus. To test the CCS under realistic conditions, it was connected to the Phase-0 CSI Evolutionary Model (CEM) at NASA Langley Research Center. The following schematic shows how the CCS is connected to the CEM. Various tests were performed which validated the ability of the system to perform control/structures experiments.

  4. Prognostic significance of Ki-67 in salivary gland carcinomas

    DEFF Research Database (Denmark)

    Larsen, Stine Rosenkilde; Bjørndal, Kristine; Godballe, Christian

    2012-01-01

    J Oral Pathol Med (2012) Background:  Salivary gland carcinomas are a heterogeneous group of tumors with varying malignant potential. In this study, we evaluated the proliferative marker Ki-67 in salivary gland carcinomas and related the Ki-67 index to clinical data. Methods:  A total of 176...... salivary gland carcinomas of 13 different subtypes were stained immunohistochemically for Ki-67. The number of Ki-67 positive cells was counted and the Ki-67 index was calculated as the percentage of positive tumor cells. Results:  The Ki-67 median value was 26 (range 1-99). The median follow-up time was 6...

  5. Adsorption and revaporisation studies of thin iodine oxide and CsI aerosol deposits from containment surface materials in LWRs

    Energy Technology Data Exchange (ETDEWEB)

    Tietze, S.; Foreman, M.; Ekberg, C. [Chalmers Univ. of Technology, Goeteborg (Sweden); Kaerkelae, T.; Auvinen, A.; Tapper, U.; Jokiniemi, J. [VTT Technical Research Centre of Finland, Espoo (Finland)

    2013-07-15

    During a severe nuclear accident released fission and radiolysis products can react with each other to form new species which might contribute to the volatile source term. Iodine will be released from UO2 fuel mainly in form as CsI aerosol particles and elemental iodine. Elemental iodine can react in gaseous phase with ozone to form solid iodine oxide aerosol particles (IOx). Within the AIAS-2 (Adsorption of Iodine Aerosols on Surfaces) project the interactions of IOx and CsI aerosols with common containment surface materials was investigated. Common surface materials in Swedish and Finnish LWRs are Teknopox Aqua V A paint films and metal surfaces such as Cu, Zn, Al and SS. Non-radioactive and {sup 131}I labelled aerosols were produced from a KI solution and ozone with a new facility designed and built at VTT Technical Research Centre of Finland. CsI aerosols were produced from a CsI solution with the same facility. A monolayer of the aerosols was deposited on the surfaces. The deposits were analysed with microscopic and spectroscopic measurement techniques to identify the chemical form of the deposits on the surfaces to identify if a chemical conversion on the different surface materials had occured. The revaporisation behaviour of the deposited aerosol particles from the different surface materials was studied under the influence of heat, humidity and gamma irradiation at Chalmers University of Technology, Sweden. Studies on the effects of humidity were performed using the FOMICAG facility, while heat and irradiation experiments were performed in a thermostated heating block and with a gammacell 22 with a dose rate of 14 kGy/h. The revaporisation losses were measured using a HPGe detector. The decomposition effect of the radiolysis product carbon monoxide was tested on IOx aerosols deposited on a glass fibre filter. Iodine oxide particles were produced at 50 deg. C, 100 deg. C and 120 deg. C and deposited on filter samples in order to study the chemical

  6. Inducing circular RNA formation using the CRISPR endoribonuclease Csy4.

    Science.gov (United States)

    Borchardt, Erin K; Meganck, Rita M; Vincent, Heather A; Ball, Christopher B; Ramos, Silvia B V; Moorman, Nathaniel J; Marzluff, William F; Asokan, Aravind

    2017-05-01

    Circular RNAs (circRNAs) are highly stable, covalently closed RNAs that are regulated in a spatiotemporal manner and whose functions are largely unknown. These molecules have the potential to be incorporated into engineered systems with broad technological implications. Here we describe a switch for inducing back-splicing of an engineered circRNA that relies on the CRISPR endoribonuclease, Csy4, as an activator of circularization. The endoribonuclease activity and 3' end-stabilizing properties of Csy4 are particularly suited for this task. Coexpression of Csy4 and the circRNA switch allows for the removal of downstream competitive splice sites and stabilization of the 5' cleavage product. This subsequently results in back-splicing of the 5' cleavage product into a circRNA that can translate a reporter protein from an internal ribosomal entry site (IRES). Our platform outlines a straightforward approach toward regulating splicing and could find potential applications in synthetic biology as well as in studying the properties of different circRNAs. © 2017 Borchardt et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society.

  7. High-power CSI-fed induction motor drive with optimal power distribution based control

    Science.gov (United States)

    Kwak, S.-S.

    2011-11-01

    In this article, a current source inverter (CSI) fed induction motor drive with an optimal power distribution control is proposed for high-power applications. The CSI-fed drive is configured with a six-step CSI along with a pulsewidth modulated voltage source inverter (PWM-VSI) and capacitors. Due to the PWM-VSI and the capacitor, sinusoidal motor currents and voltages with high quality as well as natural commutation of the six-step CSI can be obtained. Since this CSI-fed drive can deliver required output power through both the six-step CSI and PWM-VSI, this article shows that the kVA ratings of both the inverters can be reduced by proper real power distribution. The optimal power distribution under load requirements, based on power flow modelling of the CSI-fed drive, is proposed to not only minimise the PWM-VSI rating but also reduce the six-step CSI rating. The dc-link current control of the six-step CSI is developed to realise the optimal power distribution. Furthermore, a vector controlled drive for high-power induction motors is proposed based on the optimal power distribution. Experimental results verify the high-power CSI-fed drive with the optimal power distribution control.

  8. Mixed feed evaporator

    Science.gov (United States)

    Vakil, Himanshu B.; Kosky, Philip G.

    1982-01-01

    In the preparation of the gaseous reactant feed to undergo a chemical reaction requiring the presence of steam, the efficiency of overall power utilization is improved by premixing the gaseous reactant feed with water and then heating to evaporate the water in the presence of the gaseous reactant feed, the heating fluid utilized being at a temperature below the boiling point of water at the pressure in the volume where the evaporation occurs.

  9. Evaporation from microreservoirs†

    Science.gov (United States)

    Lynn, N. Scott; Henry, Charles S.

    2010-01-01

    As a result of very large surface area to volume ratios, evaporation is of significant importance when dealing with lab-on-a-chip devices that possess open air/liquid interfaces. For devices utilizing a reservoir as a fluid delivery method to a microfluidic network, excessive evaporation can quickly lead to reservoir dry out and overall device failure. Predicting the rates of evaporation from these reservoirs is difficult because the position of the air/liquid interface changes with time as the volume of liquid in the reservoir decreases. Here we present a two-step method to accurately predict the rates of evaporation of such an interface over time. First, a simple method is proposed to determine the shape of an air/liquid meniscus in a reservoir given a specific liquid volume. Second, computational fluid dynamics simulations are used to calculate the instantaneous rate of evaporation for that meniscus shape. It is shown that the rate of evaporation is strongly dependent on the overall geometry of the system, enhanced in expanding reservoirs while suppressed in contracting reservoirs, where the geometry can be easily controlled with simple experimental methods. Using no adjustable parameters, the model accurately predicts the position of the inner moving contact line as a function of time following meniscus rupture in poly(dimethylsiloxane) reservoirs, and predicts the overall time for the persistence of liquid in those reservoirs to within 0.5 minutes. The methods in this study can be used to design holding reservoirs for lab-on-a-chip devices that involve no external control of evaporation, such that evaporation rates can be adjusted as necessary by modification of the reservoir geometry. PMID:19495463

  10. Measure Guideline: Evaporative Condensers

    Energy Technology Data Exchange (ETDEWEB)

    German, A.; Dakin, B.; Hoeschele, M.

    2012-03-01

    The purpose of this measure guideline on evaporative condensers is to provide information on a cost-effective solution for energy and demand savings in homes with cooling loads. This is a prescriptive approach that outlines selection criteria, design and installation procedures, and operation and maintenance best practices. This document has been prepared to provide a process for properly designing, installing, and maintaining evaporative condenser systems as well as understanding the benefits, costs, and tradeoffs.

  11. Cognitive Power Control Under Correlated Fading and Primary-Link CSI

    CERN Document Server

    Hamza, Doha

    2009-01-01

    We consider the cognitive power control problem of maximizing the secondary throughput under an outage probability constraint on a constant-power constant-rate primary link. We assume a temporally correlated primary channel with two types of feedback: perfect delayed channel state information (CSI) and one-bit automatic repeat request (ARQ). We use channel correlation to enhance the primary and secondary throughput via exploiting the CSI feedback to predict the future primary channel gain. We provide a numerical solution for the power control optimization problem under delayed CSI. In order to make the solution tractable under ARQ-CSI, we re-formulate the cognitive power control problem as the maximization of the instantaneous weighted sum of primary and secondary throughput. We propose a greedy ARQ-CSI algorithm that is shown to achieve an average throughput comparable to that attained under the delayed-CSI algorithm, which we solve optimally.

  12. An Algorithm That Predicts CSI to Allocate Bandwidth for Healthcare Monitoring in Hospital's Waiting Rooms.

    Science.gov (United States)

    Lin, Di; Labeau, Fabrice

    2012-01-01

    In wireless healthcare monitoring systems, bandwidth allocation is an efficient solution to the problem of scarce wireless bandwidth for the monitoring of patients. However, when the central unit cannot access the exact channel state information (CSI), the efficiency of bandwidth allocation decreases, and the system performance also decreases. In this paper, we propose an algorithm to reduce the negative effects of imperfect CSI on system performance. In this algorithm, the central unit can predict the current CSI by previous CSI when the current CSI is not available. We analyze the reliability of the proposed algorithm by deducing the standard error of estimated CSI with this algorithm. In addition, we analyze the efficiency of the proposed algorithm by discussing the system performance with this algorithm.

  13. Assessment of somatic symptoms in British secondary school children using the Children's Somatization Inventory (CSI).

    Science.gov (United States)

    Vila, Mar; Kramer, Tami; Hickey, Nicole; Dattani, Meera; Jefferis, Helen; Singh, Mandeep; Garralda, M Elena

    2009-10-01

    To present normative and psychometric data on somatic symptoms using the Children's Somatization Inventory (CSI) in a nonclinical sample of British young people, and to assess associations with stress and functional impairment. A total of 1,173 students (11- to 16-years old) completed the CSI and self-report psychopathology measures. The median CSI total score was 12 (5, 23). Headaches, feeling low in energy, sore muscles, faintness, and nausea were most frequent. Girls scored higher than boys, and respondents aged 13-14 years lower than younger children. The CSI showed good internal consistency and exploratory factor analysis yielded three factors: pain/weakness, gastrointestinal, and pseudoneurological. A quarter of respondents reported somatic symptoms were made worse by stress. CSI scores were moderately significantly correlated with impairment and emotional symptoms. The CSI, complemented by information on functional impairment and stress is an appropriate measure of recent somatic symptoms and somatization risk in young people for use in the UK.

  14. KiCad challenges the big ones

    CERN Multimedia

    Antonella Del Rosso

    2015-01-01

    Printed Circuit Boards (PCB) are the heart of any electronic device, including your toaster and your smartphone. Designing PCBs is the job of electronic engineers who, so far, have often had no option but to use proprietary tools to design complex circuits. Thanks to the efforts that CERN experts have put in to improve the free KiCad software, that situation is about to change.   KiCad's development started in 1992 as a way to design PCBs, the units that control how an electronic device works. Since 2013, experts in the Beams department have made important contributions to KiCad as part of the Open Hardware Initiative (OHI), which provides a framework to facilitate knowledge exchange across the electronic design community. “Our vision is to allow the hardware developers to share as easily as their software colleagues,” says Javier Serrano, head of the BE-CO-HT section and OHI initiator. “Software sources are easily shared online because they are text ...

  15. Children's Somatization Inventory: Psychometric Properties of the Revised Form (CSI-24)

    Science.gov (United States)

    Beck, Joy E.; Garber, Judy; Lambert, Warren

    2009-01-01

    Objective To conduct a multimethod psychometric evaluation to refine the Children's Somatization Inventory (CSI) and to investigate its dimensionality. Method The CSI was administered to 876 pediatric patients with chronic abdominal pain at their initial visit to a pediatric gastroenterology clinic. Tools from three psychometric models identified items that most effectively measured the construct of somatization and examined its dimensionality. Results Eleven statistically weak items were identified and removed, creating a 24-item CSI (CSI-24). The CSI-24 showed good psychometrics according to the three measurement models and correlated.99 with the original CSI. The CSI-24 has one dominant general factor but is not strictly unidimensional. Conclusions The CSI-24 is a reliable and psychometrically sound refinement of the original CSI. Findings are consistent with the view that somatization has a strong general factor that represents a continuum of symptom reporting, as well as minor components that represent specific symptom clusters in youth with chronic abdominal pain. PMID:18782857

  16. CSI technology validation on an LSS ground experiment facility

    Science.gov (United States)

    Wang, S. J.; Eldred, D. B.

    1989-01-01

    The test bed developed at JPL for experimental evaluation of new technologies for the control of large flexible space structures is described. The experiment consists of a flexible spacecraft dynamic simulator, sensors, actuators, a microcomputer, and an advanced programming environment. The test bed has been operational for over a year, and thus far nine experiments were completed or are currently in progress. Several of these experiments were reported at the 1987 CSI conference, and several recent ones are documented in this paper, including high order adaptive control, non-parametric system identification, and mu-synthesis robust control. An aggressive program of experiments is planned for the forseeable future.

  17. CSI flight experiment projects of the Naval Research Laboratory

    Science.gov (United States)

    Fisher, Shalom

    1993-02-01

    The Naval Research Laboratory (NRL) is involved in an active program of CSI flight experiments. The first CSI flight experiment of the Naval Research Laboratory, the Low Power Atmospheric Compensation Experiment (LACE) dynamics experiment, has successfully measured vibrations of an orbiting satellite with a ground-based laser radar. The observations, made on January 7, 8 and 10, 1991, represent the first ever measurements of this type. In the tests, a narrowband heterodyne CO2 laser radar, operating at a wavelength of 10.6 microns, detected vibration induced differential-Doppler signatures of the LACE satellite. Power spectral densities of forced oscillations and modal frequencies and damping rates of free-damped vibrations were obtained and compared with finite element structural models of the LACE system. Another manifested flight experiment is the Advanced Controls Technology Experiment (ACTEX) designed to demonstrate active and passive damping with piezo-electric (PZT) sensors and actuators. This experiment was developed under the management of the Air Force Phillips Laboratory with integration of the experiment at NRL. It is to ride as a secondary, or 'piggyback,' experiment on a future Navy satellite.

  18. Perception-Induced Effects of Corporate Social Irresponsibility (CSiR) for Stereotypical and Admired Firms.

    Science.gov (United States)

    Voliotis, Seraphim; Vlachos, Pavlos A; Epitropaki, Olga

    2016-01-01

    How do stakeholders react to Corporate Social Irresponsibility (CSiR)? What are the emotional mechanisms and behavioral outcomes following CSiR perception? The psychology of CSR literature has yet to address these important questions and has largely considered CSR and CSiR as the opposite poles of the same continuum. In contrast, we view CSR and CSiR as distinct constructs and theorize about the cognitive (perceptual), emotional, and behavioral effects of CSiR activity on observers (i.e., primary and secondary stakeholders) building on theories of intergroup perception. Specifically, building on the Stereotype Content Model (SCM; Fiske et al., 2002) and the BIAS map (i.e., Behaviors from Intergroup Affect and Stereotypes; Cuddy et al., 2007)-which extends the SCM by predicting behavioral responses-we make predictions on potential stakeholder reactions to CSiR focusing on two practice-relevant cases: (a) a typical for-profit firm that engages in a CSiR activity, (b) an atypical admired firm that engages in CSiR activity.

  19. The Communication Styles Inventory (CSI): a six-dimensional behavioral model of communication styles and its relation with personality

    NARCIS (Netherlands)

    de Vries, R.E.; Bakker-Pieper, A.; Konings, F.E.; Schouten, B.

    2013-01-01

    In this study, a six-dimensional model of communication styles is proposed and operationalized using the Communication Styles Inventory (CSI). The CSI distinguishes between six domain-level communicative behavior scales, Expressiveness, Preciseness, Verbal Aggressiveness, Questioningness,

  20. Forest evaporation models: Relationships between stand growth and evaporation

    CSIR Research Space (South Africa)

    Le Maitre, David C

    1997-06-01

    Full Text Available The relationships between forest stand structure, growth and evaporation were analysed to determine whether forest evaporation can be estimated from stand growth data. This approach permits rapid assessment of the potential impacts of afforestation...

  1. Stimulated Black Hole Evaporation

    CERN Document Server

    Spaans, Marco

    2016-01-01

    Black holes are extreme expressions of gravity. Their existence is predicted by Einstein's theory of general relativity and is supported by observations. Black holes obey quantum mechanics and evaporate spontaneously. Here it is shown that a mass rate $R_f\\sim 3\\times 10^{-8} (M_0/M)^{1/2}$ $M_0$ yr$^{-1}$ onto the horizon of a black hole with mass $M$ (in units of solar mass $M_0$) stimulates a black hole into rapid evaporation. Specifically, $\\sim 3 M_0$ black holes can emit a large fraction of their mass, and explode, in $M/R_f \\sim 3\\times 10^7 (M/M_0)^{3/2}$ yr. These stimulated black holes radiate a spectral line power $P \\sim 2\\times 10^{39} (M_0/M)^{1/2}$ erg s$^{-1}$, at a wavelength $\\lambda \\sim 3\\times 10^5 (M/M_0)$ cm. This prediction can be observationally verified.

  2. Vloga medicinske sestre v ergooftalmološki ambulanti

    OpenAIRE

    Deželak, Maja

    2012-01-01

    V diplomskem delu je predstavljena vloga medicinske sestre v dispanzerju Medicine dela, prometa in športa, s posebnim poudarkom v ergooftelmološki ambulanti (opisane so vrste preventivnih pregledov in mnenja o delazmožnosti). Predstavljeni so pregledi vida in preiskave vidnega polja ter naloge in dokumentiranje medicinske sestre v ergooftalmološki ambulanti. V empiričnem delu je predstavljena raziskava, ki je bila izvedena med pacienti, ki so obiskali dispanzer medicine dela, prometa in šport...

  3. Water Membrane Evaporator

    Science.gov (United States)

    Ungar, Eugene K.; Almlie, Jay C.

    2010-01-01

    A water membrane evaporator (WME) has been conceived and tested as an alternative to the contamination-sensitive and corrosion-prone evaporators currently used for dissipating heat from space vehicles. The WME consists mainly of the following components: An outer stainless-steel screen that provides structural support for the components mentioned next; Inside and in contact with the stainless-steel screen, a hydrophobic membrane that is permeable to water vapor; Inside and in contact with the hydrophobic membrane, a hydrophilic membrane that transports the liquid feedwater to the inner surface of the hydrophobic membrane; Inside and in contact with the hydrophilic membrane, an annular array of tubes through which flows the spacecraft coolant carrying the heat to be dissipated; and An inner exclusion tube that limits the volume of feedwater in the WME. In operation, a pressurized feedwater reservoir is connected to the volume between the exclusion tube and the coolant tubes. Feedwater fills the volume, saturates the hydrophilic membrane, and is retained by the hydrophobic membrane. The outside of the WME is exposed to space vacuum. Heat from the spacecraft coolant is conducted through the tube walls and the water-saturated hydrophilic membrane to the liquid/vapor interface at the hydrophobic membrane, causing water to evaporate to space. Makeup water flows into the hydrophilic membrane through gaps between the coolant tubes.

  4. Potniški center Ljubljana

    Directory of Open Access Journals (Sweden)

    Matej Nikšič

    2002-01-01

    Full Text Available Natečaj je bil razpisan v želji prekiniti mrtvi tek, v katerem se je znašlo urejanje ljubljanske prometne glave in nanjo vezanih projektov. Ob spremenjenih družbeno-političnih okoliščinah in mednarodnemu povabilu k udeležbi so se obetale sveže in z lokalnimi kapricami neobremenjene ideje, ki pa jih, tudi zaradi togih konceptualnih in tehničnih predpisov v izhodiščih natečaja, ni bilo dosti. Predstavljeni predlogi v danih okvirih rešujejo osnovno nalogo, s svojo konvencionalnostjo pa ne prinašajo bistvenih novosti v urejanje območja z visokim mestotvornim potencialom.

  5. Relay Precoder Optimization in MIMO-Relay Networks With Imperfect CSI

    KAUST Repository

    Pandarakkottilil, Ubaidulla

    2011-11-01

    In this paper, we consider robust joint designs of relay precoder and destination receive filters in a nonregenerative multiple-input multiple-output (MIMO) relay network. The network consists of multiple source-destination node pairs assisted by a MIMO-relay node. The channel state information (CSI) available at the relay node is assumed to be imperfect. We consider robust designs for two models of CSI error. The first model is a stochastic error (SE) model, where the probability distribution of the CSI error is Gaussian. This model is applicable when the imperfect CSI is mainly due to errors in channel estimation. For this model, we propose robust minimum sum mean square error (SMSE), MSE-balancing, and relay transmit power minimizing precoder designs. The next model for the CSI error is a norm-bounded error (NBE) model, where the CSI error can be specified by an uncertainty set. This model is applicable when the CSI error is dominated by quantization errors. In this case, we adopt a worst-case design approach. For this model, we propose a robust precoder design that minimizes total relay transmit power under constraints on MSEs at the destination nodes. We show that the proposed robust design problems can be reformulated as convex optimization problems that can be solved efficiently using interior-point methods. We demonstrate the robust performance of the proposed design through simulations. © 2011 IEEE.

  6. CSI 2.0: a significantly improved version of the Chemical Shift Index.

    Science.gov (United States)

    Hafsa, Noor E; Wishart, David S

    2014-11-01

    Protein chemical shifts have long been used by NMR spectroscopists to assist with secondary structure assignment and to provide useful distance and torsion angle constraint data for structure determination. One of the most widely used methods for secondary structure identification is called the Chemical Shift Index (CSI). The CSI method uses a simple digital chemical shift filter to locate secondary structures along the protein chain using backbone (13)C and (1)H chemical shifts. While the CSI method is simple to use and easy to implement, it is only about 75-80% accurate. Here we describe a significantly improved version of the CSI (2.0) that uses machine-learning techniques to combine all six backbone chemical shifts ((13)Cα, (13)Cβ, (13)C, (15)N, (1)HN, (1)Hα) with sequence-derived features to perform far more accurate secondary structure identification. Our tests indicate that CSI 2.0 achieved an average identification accuracy (Q3) of 90.56% for a training set of 181 proteins in a repeated tenfold cross-validation and 89.35% for a test set of 59 proteins. This represents a significant improvement over other state-of-the-art chemical shift-based methods. In particular, the level of performance of CSI 2.0 is equal to that of standard methods, such as DSSP and STRIDE, used to identify secondary structures via 3D coordinate data. This suggests that CSI 2.0 could be used both in providing accurate NMR constraint data in the early stages of protein structure determination as well as in defining secondary structure locations in the final protein model(s). A CSI 2.0 web server (http://csi.wishartlab.com) is available for submitting the input queries for secondary structure identification.

  7. Cross cultural adaptation and psychometric validation of the Serbian version of the Central Sensitization Inventory (CSI).

    Science.gov (United States)

    Knezevic, Aleksandar; Neblett, Randy; Jeremic-Knezevic, Milica; Tomasevic-Todorovic, Snezana; Boskovic, Ksenija; Colovic, Petar; Cuesta-Vargas, Antonio

    2017-08-04

    It has been increasingly recognized that many chronic pain conditions are associated with central sensitization (CS). The Central Sensitization Inventory (CSI) is a potentially useful tool for screening patients whose presenting symptoms are suspected of being related to CS, so that additional diagnostic evaluation can be performed, and appropriate treatment can be initiated. The original English version is currently not available in Serbian. The CSI was translated into Serbian and then psychometrically evaluated in a sample of 363 chronic pain subjects. The CSI-Serb showed a high degree of internal consistency (Cronbach's alpha = 0.909), excellent test-retest reliability (ICC2,1 =0.947), and a significant goodness of fit test χ(2) =888.44; pCSI, with all items retained. Higher CSI-Serb scores were associated with higher pain severity and longer pain duration. Total CSI scores distinguished between three subject groups, with presumably different levels of CS, including fibromyalgia (53.3, SD=11.2), chronic regional pain only (29.7, SD=11.6), and a pain-free control group (20.9, SD=9.1). The results of the present study indicated strong psychometric properties, including evidence of convergent and discriminant validity, of the Serbian version of the CSI. These results correspond with other translated versions of the CSI that have been psychometrically evaluated and published. Due to the current interest in CS, and its relationship with many chronic pain conditions, it is anticipated that the CSI-Serb will benefit Serbian-speaking clinicians in the evaluation of patients with chronic pain conditions. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  8. Structural transformation of CsI thin film photocathodes under exposure to air and UV irradiation

    CERN Document Server

    Tremsin, A S; Siegmund, O H W

    2000-01-01

    Transmission electron microscopy has been employed to study the structure of polycrystalline CsI thin films and its transformation under exposure to humid air and UV irradiation. The catastrophic degradation of CsI thin film photocathode performance is shown to be associated with the film dissolving followed by its re-crystallization. This results in the formation of large lumps of CsI crystal on the substrate surface, so that the film becomes discontinuous and its performance as a photocathode is permanently degraded. No change in the surface morphology and the film crystalline structure was observed after the samples were UV irradiated.

  9. Reexamining the Factor structure of somatization using the children's somatization inventory (CSI-24) in a community sample.

    Science.gov (United States)

    Lavigne, John V; Saps, Miguel; Bryant, Fred B

    2012-09-01

    Pediatric somatization studies have used the 35-item Child Somatization Inventory (CSI-35) or psychometrically refined 24-item CSI (CSI-24). Exploratory factor analysis of the CSI-24 has identified a single factor that did not show good model fit in confirmatory factor analysis (CFA). Further evaluation of the CSI-24 factor structure is needed. The present study examined alternative factor structures of the CSI-24 in a community sample (N = 233, ages 8-15). The CFA showed good fit for a single CSI-24 factor, better fit for multiple factor models, and best fit for a single, six-item factor. Construct validity for that factor was found in significant correlations with anxiety, depression, functional disability, and quality of life. Results are consistent with a single somatization factor, but research is needed to verify the factor structure in different, race/ethnic/demographic, and clinical groups.

  10. Evaporation and Antievaporation Instabilities

    Directory of Open Access Journals (Sweden)

    Andrea Addazi

    2017-10-01

    Full Text Available We review (antievaporation phenomena within the context of quantum gravity and extended theories of gravity. The (antievaporation effect is an instability of the black hole horizon discovered in many different scenarios: quantum dilaton-gravity, f ( R -gravity, f ( T -gravity, string-inspired black holes, and brane-world cosmology. Evaporating and antievaporating black holes seem to have completely different thermodynamical features compared to standard semiclassical black holes. The purpose of this review is to provide an introduction to conceptual and technical aspects of (antievaporation effects, while discussing problems that are still open.

  11. Indirect evaporative cooling systems

    Energy Technology Data Exchange (ETDEWEB)

    Wooldridge, M.J.; Chapman, H.L.; Pescod, D.

    1976-01-01

    Characteristics and applications of three indirect evaporative cooling systems are described. The rock bed regenerative unit is now in licensed production and some operational experience is available, while the plastic plate heat exchanger unit has been demonstrated to be effective. A third system, based on a rotary heat exchanger is included. Although less development has been done on it, several successful applications of the heat exchanger are operational. All systems provide comfort cooling in which building indoor temperature varies over the day at an operating cost less than 50% of that of a comparable refrigerated cooling system.

  12. Secure Communication for Two-Way Relay Networks with Imperfect CSI

    National Research Council Canada - National Science Library

    Cong Sun; Ke Liu; Dahu Zheng; Wenbao Ai

    2017-01-01

    This paper considers a two-way relay network, where two legitimate users exchange messages through several cooperative relays in the presence of an eavesdropper, and the Channel State Information (CSI...

  13. Investigating CSI: portrayals of DNA testing on a forensic crime show and their potential effects.

    Science.gov (United States)

    Ley, Barbara L; Jankowski, Natalie; Brewer, Paul R

    2012-01-01

    The popularity of forensic crime shows such as CSI has fueled debate about their potential social impact. This study considers CSI's potential effects on public understandings regarding DNA testing in the context of judicial processes, the policy debates surrounding crime laboratory procedures, and the forensic science profession, as well as an effect not discussed in previous accounts: namely, the show's potential impact on public understandings of DNA and genetics more generally. To develop a theoretical foundation for research on the "CSI effect," it draws on cultivation theory, social cognitive theory, and audience reception studies. It then uses content analysis and textual analysis to illuminate how the show depicts DNA testing. The results demonstrate that CSI tends to depict DNA testing as routine, swift, useful, and reliable and that it echoes broader discourses about genetics. At times, however, the show suggests more complex ways of thinking about DNA testing and genetics.

  14. Gábor Munkácsi tekstiilid Tallinnas / Kadi Raudalainen

    Index Scriptorium Estoniae

    Raudalainen, Kadi

    1999-01-01

    22. okt.-st Lühikese jala galeriis ungari tekstiilikunstniku Gábor Munkácsi tööde näitus. Enamik tekstiilidest on valmistatud igivanas ikat-tehnikas. Eksponeeritud kardinad, seinatekstiilid, laudlinad

  15. The Census of Social Institutions (CSI): a public health direct observation measure of local land use.

    Science.gov (United States)

    Heinrich, Katie M; Hughey, Joseph; Randles, Anthony; Wall, Dustin; Peterson, N Andrew; Jitnarin, Nattinee; Berkel, LaVerne; Eaton, Peter; Bowles, Doug; Haddock, C Keith; Poston, W S Carlos

    2010-05-01

    This manuscript describes the development of the Census of Social Institutions (CSI), a reliable direct observation parcel-level built environment measure. The CSI was used to measure all non-residential parcels (n = 10,842) in 21 one-mile-radius neighborhoods centered around census block groups of varying income and ethnicity in a large metropolitan area. One year test-retest and inter-rater intra-class correlations showed high reliability for major use type and detail code observations. The CSI accurately captured the presence of about 9,500 uses, including 828 multiple major use and 431 mixed major use parcels that would have been missed in standard commercial databases. CSI data can be utilized to determine the health impacts of environmental settings.

  16. Role of the substrate reflectance and surface-bulk treatments in CsI quantum efficiency

    CERN Document Server

    Singh, B K; Nitti, M A; Valentini, A

    2003-01-01

    We have experimentally investigated the following aspects related to the quantum efficiency of CsI photocathodes: the type of substrate, the film thickness and the effect of a 'bulk treatment' during the film growth. We discovered that, using a high reflectivity aluminium substrate, the photoemission of very thin CsI film is enhanced. Our study also revealed that photocathodes become less sensitive to moisture when a negative bias voltage is applied to the substrate during the film deposition process.

  17. Measurement of the evolution of the CsI quantum efficiency in gas photon detectors

    Science.gov (United States)

    Alexeev, M.; Birsa, R.; Bradamante, F.; Bressan, A.; Dalla Torre, S.; Duic, V.; Giorgi, M.; Gobbo, B.; Levorato, S.; Martin, A.; Sbrizzai, G.; Schiavon, P.; Sozzi, F.; Tessarotto, F.

    2014-12-01

    We present an indirect measurement of possible long term variations of the CsI quantum efficiency in solid state photocathodes in MWPC. This type of photon detectors has been used since 2001 in the Cherenkov Imaging detector RICH-1 of the COMPASS experiment at CERN SPS. Data from six years of COMPASS data taking are used to evaluate the mean number of detected photons per particle. The results do not indicate any severe CsI quantum efficiency ageing effect.

  18. TOTAL NUCLEAR-REACTION PROBABILITY OF 270 TO 390 N-14 IONS IN SI AND CSI

    NARCIS (Netherlands)

    WARNER, RE; CARPENTER, CL; FETTER, JM; WAITE, WF; WILSCHUT, HW; HOOGDUIN, JM

    A magnetic spectrograph and position-sensitive detectors were used to measure the total nuclear reaction probability eta(R) for alpha + CsI at 116 MeV, N-14 + CsI at 265 and 385 MeV, and N-14 + Si at 271 and 390 MeV. From these eta(R)'s, average reaction cross sections sigma(R) were deduced for

  19. Development of an automatical identification method in the CsI detectors; Develppement d`une method automatique d`identification dans les detecteurs CsI

    Energy Technology Data Exchange (ETDEWEB)

    Gourio, D. [Gesellschaft fuer Schwerionenforschung, Planckstrasse 1, D-64291 Darmstadt (Germany); Assenard, M.; Germain, M.; Reposeur, T.; Eudes, P.; Lautridou, P.; Laville, J.L.; Lebrun, C.; Rahmani, A. [Laboratoire de Physique Subatomique et des Technologies Associees - SUBATECH, Centre National de la Recherche Scientifique, 44 - Nantes (France)

    1997-10-01

    Achievement of multidetectors offers the possibility of measuring almost totally the particles produced in heavy ion reactions. Particularly, INDRA covers 90% of the solid angle and uses some 350 CsI detectors for the charged particle detection (Z {<=} 4). As the data yield from these multidetectors is huge we developed a first approach to automatically perform the identification procedure for light particle in a CsI scintillator. This is based on a pattern recognition with a final check assuring the consistency of the result

  20. CSI-Tree: a regression tree approach for modeling binding properties of DNA-binding molecules based on cognate site identification (CSI) data.

    Science.gov (United States)

    Keleş, Sündüz; Warren, Christopher L; Carlson, Clayton D; Ansari, Aseem Z

    2008-06-01

    The identification and characterization of binding sites of DNA-binding molecules, including transcription factors (TFs), is a critical problem at the interface of chemistry, biology and molecular medicine. The Cognate Site Identification (CSI) array is a high-throughput microarray platform for measuring comprehensive recognition profiles of DNA-binding molecules. This technique produces datasets that are useful not only for identifying binding sites of previously uncharacterized TFs but also for elucidating dependencies, both local and nonlocal, between the nucleotides at different positions of the recognition sites. We have developed a regression tree technique, CSI-Tree, for exploring the spectrum of binding sites of DNA-binding molecules. Our approach constructs regression trees utilizing the CSI data of unaligned sequences. The resulting model partitions the binding spectrum into homogeneous regions of position specific nucleotide effects. Each homogeneous partition is then summarized by a position weight matrix (PWM). Hence, the final outcome is a binding intensity rank-ordered collection of PWMs each of which spans a different region in the binding spectrum. Nodes of the regression tree depict the critical position/nucleotide combinations. We analyze the CSI data of the eukaryotic TF Nkx-2.5 and two engineered small molecule DNA ligands and obtain unique insights into their binding properties. The CSI tree for Nkx-2.5 reveals an interaction between two positions of the binding profile and elucidates how different nucleotide combinations at these two positions lead to different binding affinities. The CSI trees for the engineered DNA ligands exhibit a common preference for the dinucleotide AA in the first two positions, which is consistent with preference for a narrow and relatively flat minor groove. We carry out a reanalysis of these data with a mixture of PWMs approach. This approach is an advancement over the simple PWM model and accommodates position

  1. Representative shuttle evaporative heat sink

    Science.gov (United States)

    Hixon, C. W.

    1978-01-01

    The design, fabrication, and testing of a representative shuttle evaporative heat sink (RSEHS) system which vaporizes an expendable fluid to provide cooling for the shuttle heat transport fluid loop is reported. The optimized RSEHS minimum weight design meets or exceeds the shuttle flash evaporator system requirements. A cold trap which cryo-pumps flash evaporator exhaust water from the CSD vacuum chamber test facility to prevent water contamination of the chamber pumping equipment is also described.

  2. Reproducibility of rapid short echo time CSI at 3 tesla for clinical applications.

    Science.gov (United States)

    Van Cauter, Sofie; Sima, Diana M; Luts, Jan; ter Beek, Leon; Ribbens, Annemie; Peeters, Ronald R; Osorio Garcia, Maria I; Li, Yuquan; Sunaert, Stefan; Van Gool, Stefaan W; Van Huffel, Sabine; Himmelreich, Uwe

    2013-02-01

    To validate the reproducibility of a chemical shift imaging (CSI) acquisition protocol with parallel imaging, using automated repositioning software. Ten volunteers were imaged three times on two different 3 Tesla (T) MRI scanners, receiving anatomical imaging and two identical CSI measurements, using automated repositioning software for consistent repositioning of the CSI grid. Offcenter parameters of the CSI plane were analyzed. Coefficients of variation (CoV), Cramér-Rao lower bounds (CRLB), intraclass correlation coefficients (ICC), and coefficients of repeatability (CoR) for immediate repetition and between scanners were calculated for N-acetylaspartate, total choline, creatine, myo-inositol (Myo) and glutamine+glutamate (Glx). Proportions of variance reflecting the effect of voxel location, volunteer, repetition, time instance and scanner were calculated from an analysis of variance analysis. The offcenter vector and angulations of the CSI grid differed less than 1 mm and 2° between all measurements. The mean CoV and CRLB were less than 30% for all metabolites, except for Myo. The variance due to voxel location in the volume of interest and the error represent the largest contributions in variability. The ICC is the lowest for Myo and Glx. CoR for immediate repetition and between scanners display values between 22 and 83%. We propose a CSI protocol with acceptable reproducibility, applicable in clinical routine. Copyright © 2012 Wiley Periodicals, Inc.

  3. The Mu2e Undoped CsI Crystal Calorimeter

    Energy Technology Data Exchange (ETDEWEB)

    Atanov, N.; et al.

    2018-01-07

    The Mu2e experiment at Fermilab will search for Charged Lepton Flavor Violating conversion of a muon to an electron in an atomic field. The Mu2e detector is composed of a tracker, an electromagnetic calorimeter and an external system, surrounding the solenoid, to veto cosmic rays. The calorimeter plays an important role to provide: a) excellent particle identification capabilities; b) a fast trigger filter; c) an easier tracker track reconstruction. Two disks, located downstream of the tracker, contain 674 pure CsI crystals each. Each crystal is read out by two arrays of UV-extended SiPMs. The choice of the crystals and SiPMs has been finalized after a thorough test campaign. A first small scale prototype consisting of 51 crystals and 102 SiPM arrays has been exposed to an electron beam at the BTF (Beam Test Facility) in Frascati. Although the readout electronics were not the final, results show that the current design is able to meet the timing and energy resolution required by the Mu2e experiment.

  4. modeling of evaporation modeling of evaporation losses in sewage ...

    African Journals Online (AJOL)

    eobe

    A model for evaporation losses in sewage sludge drying bed was derived from first principles. This model was developed based on the reasoning that the rate at which evaporation is taking place is directly proportional to the instantaneous quantity of water in the sludge. The aim of this work was to develop a model to.

  5. Ki wa ja loodus / Martin Rünkla

    Index Scriptorium Estoniae

    Rünk, Martin

    2010-01-01

    Ki wa näitus "Wildlife documentaries" ("Looduse valetõlked") Tallinnas Draakoni galeriis 23. jaanuarini 2010. Eksponeeritud mustvalged tekstimaalid. Kunstnik tõlgendab looduspilte ja helisid tekstina

  6. Michelangelo müüki / Maria-Kristiina Soomre

    Index Scriptorium Estoniae

    Soomre, Maria-Kristiina, 1978-

    2001-01-01

    2000. a. Põhja-Yorkshire's leitud Michelangelo tushijoonistus läheb 11. VI Londonis Sotheby oksjonil müüki. Hinnaks prognoositakse 8 miljonit naela. Etüüd leinavast naisest on dateeritud ajavahemikku 1494-1504.

  7. Azithromycin analogue CSY0073 attenuates lung inflammation induced by LPS challenge

    Science.gov (United States)

    Balloy, V; Deveaux, A; Lebeaux, D; Tabary, O; le Rouzic, P; Ghigo, J M; Busson, P F; Boëlle, P Y; Guez, J Guez; Hahn, U; Clement, A; Chignard, M; Corvol, H; Burnet, M; Guillot, L

    2014-01-01

    Background and Purpose Azithromycin is a macrolide antibiotic with anti-inflammatory and immunomodulating effects. Long-term azithromycin therapy in patients with chronic lung diseases such as cystic fibrosis has been associated with increased antimicrobial resistance, emergence of hypermutable strains, ototoxicity and cardiac toxicity. The aim of this study was to assess the anti-inflammatory effects of the non-antibiotic azithromycin derivative CSY0073. Experimental Approach We compared the effects of CSY0073 with those of azithromycin in experiments on bacterial cultures, Pseudomonas aeruginosa biofilm, lung cells and mice challenged intranasally with P. aeruginosa LPS. Key Results In contrast to azithromycin, CSY0073 did not inhibit the growth of P. aeruginosa, Staphylococcus aureus or Haemophilus influenzae and had no effect on an established P. aeruginosa biofilm. Bronchoalveolar lavage (BAL) fluids and lung homogenates collected after the LPS challenge in mice showed that CSY0073 and azithromycin (200 mg·kg−1, i.p.) decreased neutrophil counts at 24 h and TNF-α, CXCL1 and CXCL2 levels in the BAL fluid after 3 h and IL-6, CXCL2 and IL-1β levels in the lung after 3 h compared with the vehicle. However, only azithromycin reduced IL-1β levels in the lung 24 h post LPS challenge. CSY0073 and azithromycin similarly diminished the production of pro-inflammatory cytokines by macrophages, but not lung epithelial cells, exposed to P. aeruginosa LPS. Conclusions and Implications Unlike azithromycin, CSY0073 had no antibacterial effects but it did have a similar anti-inflammatory profile to that of azithromycin. Hence, CSY0073 may have potential as a long-term treatment for patients with chronic lung diseases. PMID:24417187

  8. Zaslužki trgovine z ljudmi v Sloveniji

    OpenAIRE

    Kosem, Špela

    2016-01-01

    V diplomskem delu predstavljamo problematiko trgovine z ljudmi v Sloveniji. Uradne statistike velikega dela trgovine z ljudmi ne zajamejo, saj je velik del ostaja neodkrite ali nedokazane. Podatke in ocene zato v diplomskem delu pridobivamo s poglobljenimi intervjuju z zaposlenimi, ki se pri svojem delu neposredno srečujejo s primeri in posledicami trgovine z ljudmi. Z analizo rezultatov ugotavljamo, da so dobički v trgovini z ljudmi zlasti v razmerju s tveganji za trgovce izjemno visoki, vel...

  9. Evaporative cooling: Effective latent heat of evaporation in relation to evaporation distance from the skin

    NARCIS (Netherlands)

    Havenith, G.; Bröde, P.; Hartog, E.A. den; Kuklane, K.; Holmer, I.; Rossi, R.M.; Richards, M.; Farnworth, B.; Wang, X.

    2013-01-01

    Calculation of evaporative heat loss is essential to heat balance calculations. Despite recognition that the value for latent heat of evaporation, used in these calculations, may not always reflect the real cooling benefit to the body, only limited quantitative data on this is available, which has

  10. Lake Evaporation: a Model Study

    Science.gov (United States)

    Amayreh, Jumah Ahmad

    1995-01-01

    Reliable evaporation data are an essential requirement in any water and/or energy budget studies. This includes operation and management of both urban and agricultural water resources. Evaporation from large, open water surfaces such as lakes and reservoirs may influence many agricultural and irrigation decisions. In this study evaporation from Bear Lake in the states of Idaho and Utah was measured using advanced research instruments (Bowen Ratio and Eddy Correlation). Actual over-lake evaporation and weather data measurements were used to understand the mechanism of evaporation in the lake, determine lake-related parameters (such as roughness lengths, heat storage, net radiation, etc.), and examine and evaluate existing lake evaporation methods. This enabled the development of a modified and flexible model incorporating the tested methods for hourly and daily best estimates of lake evaporation using nearby simple land-based weather data and, if available, remotely sensed data. Average evaporation from Bear Lake was about 2 mm/day during the summer season (March-October) of this two-year (1993-1994) study. This value reflects the large amount of energy consumed in heating the water body of the lake. Moreover, evaporation from the lake was not directly related to solar radiation. This observation was clear during night time when the evaporation continued with almost the same rate as daytime evaporation. This explains the vital role of heat storage in the lake as the main driving energy for evaporation during night time and day time cloudy sky conditions. When comparing over-lake and nearby land-based weather parameters, land-based wind speed was the only weather parameter that had a significant difference of about 50% lower than over-lake measurements. Other weather parameters were quite similar. The study showed that evaporation from the lake can be accurately estimated using Penman-type equations if related parameters such as net radiation, heat storage, and

  11. Visualization of a City Sustainability Index (CSI: Towards Transdisciplinary Approaches Involving Multiple Stakeholders

    Directory of Open Access Journals (Sweden)

    Koichiro Mori

    2015-09-01

    Full Text Available We have developed a visualized 3-D model of a City Sustainability Index (CSI based on our original concept of city sustainability in which a sustainable city is defined as one that maximizes socio-economic benefits while meeting constraint conditions of the environment and socio-economic equity on a permanent basis. The CSI is based on constraint and maximization indicators. Constraint indicators assess whether a city meets the necessary minimum conditions for city sustainability. Maximization indicators measure the benefits that a city generates in socio-economic aspects. When used in the policy-making process, the choice of constraint indicators should be implemented using a top-down approach. In contrast, a bottom-up approach is more suitable for defining maximization indicators because this technique involves multiple stakeholders (in a transdisciplinary approach. Using different materials of various colors, shapes, sizes, we designed and constructed the visualized physical model of the CSI to help people evaluate and compare the performance of different cities in terms of sustainability. The visualized model of the CSI can convey complicated information in a simple and straightforward manner to diverse stakeholders so that the sustainability analysis can be understood intuitively by ordinary citizens as well as experts. Thus, the CSI model helps stakeholders to develop critical thinking about city sustainability and enables policymakers to make informed decisions for sustainability through a transdisciplinary approach.

  12. Multileg Heat-Pipe Evaporator

    Science.gov (United States)

    Alario, J. P.; Haslett, R. A.

    1986-01-01

    Parallel pipes provide high heat flow from small heat exchanger. Six parallel heat pipes extract heat from overlying heat exchanger, forming evaporator. Vapor channel in pipe contains wick that extends into screen tube in liquid channel. Rods in each channel hold wick and screen tube in place. Evaporator compact rather than extended and more compatible with existing heat-exchanger geometries. Prototype six-pipe evaporator only 0.3 m wide and 0.71 m long. With ammonia as working fluid, transports heat to finned condenser at rate of 1,200 W.

  13. Intrinsic Evaporative Cooling by Hygroscopic Earth Materials

    National Research Council Canada - National Science Library

    Rempel, Alexandra; Rempel, Alan

    2016-01-01

    .... Diverse evaporative cooling strategies have resulted worldwide, including roof ponds and sprinklers, courtyard fountains, wind catchers with qanats, irrigated green roofs, and fan-assisted evaporative coolers...

  14. Prothymosin-alpha and Ki-67 expression in pituitary adenomas

    Directory of Open Access Journals (Sweden)

    Iga Wierzbicka-Tutka

    2016-11-01

    Full Text Available Introduction: Prothymosin alpha (PTMA, a nuclear oncoprotein involved in cell cycle regulation, is used as a prognostic marker in many cancers. The histopathology of pituitary carcinomas and locally invasive adenomas is indistinguishable from that of benign tumors. A new marker is needed to differentiate these lesions. We evaluated PTMA in pituitary adenomas to determine its usefulness as a prognostic factor of tumor proliferation.Material/Methods: We conducted a retrospective analysis of a group of 27 patients, including 15 females (56% and 12 males (44% with a mean age of 58.6±12 years, who underwent pituitary tumor surgery between 2003 and 2012. The Ki-67 and PTMA-nuclear (PTMA-n and PTMA-cytoplasmic (PTMA-c indices were determined by immunohistochemical staining. We studied histopathological features, clinical symptoms, and magnetic resonance imaging or computed tomography performed before surgery and one year following surgery to evaluate tumor size and progression.Results: The expression of Ki-67 was revealed in 77.8% of adenomas, PTMA-n in 81.5% and PTMA-c in 92.6%. The mean value of the Ki-67 index was 1.8%, PTMA-n was 1.84%, and PTMA-c was 35.6%. There was a significant positive correlation between Ki-67 and PTMA-n (p=0.009. We did not find any correlation between Ki-67, PTMA-c, and tumor progression. PTMA-n was found to be correlated with tumor size (p=0.045 and was higher in the case of gonadotropinomas (p=0.026.Conclusions: The positive nuclear expression of Ki-67 and PTMA was observed in the majority of pituitary adenomas. Neither the expression of Ki-67 nor that of PTMA-c was related to tumor recurrence or local invasion.

  15. Ki-67 expression in anal intraepithelial neoplasia in AIDS

    Directory of Open Access Journals (Sweden)

    Edenilson Eduardo Calore

    2001-05-01

    Full Text Available CONTEXT: AIDS is one of the most important risk factors for progression and recurrence of anogenital condyloma. In a previous work, we observed that patients with warts and high-grade AIN (HAIN had recurrences more frequently than did patients with warts without AIN. The mechanisms of this increased incidence of high-grade lesions in AIDS are not known. OBJECTIVE: We studied the expression of the proliferative marker Ki-67 by immunohistochemical methods, in specimens of anal condyloma from HIV+ patients to clarify whether its expression can be associated to the grade of AIN. DESIGN: A retrospective study of hiltological specimens. SETTING: University referral unit. SAMPLE: 34 patients were divided into two groups: (1 condylomas with low grade AIN (LAIN, with 25 patients; and (2 condylomas with HAIN, with 9 patients. In this latter group we examined two areas: 2A (HAIN area and 2B (LAIN area. MAIN MEASUREMENTS: The immunohistochemical reaction for Ki-67 was done on histological sections. Slices were lightly stained with hematoxylin, to help us in Ki-67 positive cell counting. The percentage of Ki-67 marked nuclei was calculated. We applied one-way variance analysis for statistics. RESULTS: The mean number of Ki-67 positive cells in group 1 was 19.68 ± 10.99; in group 2 (area A it was 46.73 ± 10.409; and in area B it was 36.43 ± 14.731. There were statistical differences between groups 1 and 2A and between groups 1 and 2B. Ki-67 positive cells predominated in the lower layer in LAIN. Positive Ki-67 cells were found in all layers in group 2A, and in group 2B they predominated in the two lower or in all layers of the epithelium. CONCLUSIONS: Our results suggest that LAIN areas (using routine staining techniques in HAIN can have a biological behavior more similar to HAIN.

  16. Secrecy performance analysis of SIMO underlay cognitive radio systems with outdated CSI

    KAUST Repository

    Lei, Hongjiang

    2017-06-13

    This study investigates the secrecy outage performance of a single-input multiple-output underlay cognitive radio network (CRN) with outdated channel state information (CSI). The confidential messages are transmitted from transmitter to the destination, while a multi-antenna eavesdropper exists. The maximal ratio combining and selection combining schemes are utilised at the receivers to improve the quality of the received signal-to-noise ratio. The exact and asymptotic closed-form expressions of secrecy outage probability are derived, and simulation results are provided to verify the authors\\' proposed analytical results. The results reveal that imperfect CSI of main channels deteriorates the secrecy outage performance while that of eavesdropping and interfering channels has contrary effect, and only a unity diversity order can be obtained in underlay CRNs with imperfect CSI.

  17. Measurement of the evolution of the CsI quantum efficiency in gas photon detectors

    Energy Technology Data Exchange (ETDEWEB)

    Alexeev, M.; Birsa, R. [INFN, Sezione di Trieste, Trieste (Italy); Bradamante, F.; Bressan, A. [INFN, Sezione di Trieste and University of Trieste, Trieste (Italy); Dalla Torre, S., E-mail: silvia.dallatorre@ts.infn.it [INFN, Sezione di Trieste, Trieste (Italy); Duic, V.; Giorgi, M. [INFN, Sezione di Trieste and University of Trieste, Trieste (Italy); Gobbo, B.; Levorato, S. [INFN, Sezione di Trieste, Trieste (Italy); Martin, A.; Sbrizzai, G.; Schiavon, P. [INFN, Sezione di Trieste and University of Trieste, Trieste (Italy); Sozzi, F.; Tessarotto, F. [INFN, Sezione di Trieste, Trieste (Italy)

    2014-12-01

    We present an indirect measurement of possible long term variations of the CsI quantum efficiency in solid state photocathodes in MWPC. This type of photon detectors has been used since 2001 in the Cherenkov Imaging detector RICH-1 of the COMPASS experiment at CERN SPS. Data from six years of COMPASS data taking are used to evaluate the mean number of detected photons per particle. The results do not indicate any severe CsI quantum efficiency ageing effect. - Highlights: • We determine the evolution of the CsI effective quantum efficiency. • We analyse samples of COMPASS RICH-1 from six years. • The integrated ion backflow to the photocathodes is below 10μC/cm{sup 2}. • The data indicate at most a very low rate QE reduction of a few per cent per year. • The result is relevant for MPGD-based photon counters presently under development.

  18. Influence of bias voltage on the stability of CsI photocathodes exposed to air

    CERN Document Server

    Nitti, M A; Nappi, E; Singh, B K; Valentini, A

    2002-01-01

    We describe a possible correlation between the bias voltage applied to the substrate during the growth of CsI photocathodes and the variation of quantum efficiency (QE) after one day exposure to humid air. It was found that fresh samples are much less sensitive to humid air when a high negative bias voltage was applied during film growth. A model based on surface film interaction with water molecules is presented for the observed effect. X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS) measurements have been performed to examine, respectively, the bulk structure and the surface of fresh and exposed CsI samples. Also reported are transmittance measurements for fresh and aged CsI samples in the wavelength range 190-850 nm.

  19. Performance Analysis of Communications under Energy Harvesting Constraints with noisy CSI

    KAUST Repository

    Znaidi, Mohamed Ridha Ali

    2016-01-06

    In energy harvesting communications, the transmitters have to adapt transmission to availability of energy harvested during the course of communication. The performance of the transmission depends on the channel conditions which vary randomly due to environmental changes. In this work, we consider the problem of power allocation taking into account the energy arrivals over time and the degree of channel state information (CSI) available at the transmitter, to maximize the throughput. Differently from previous work, the CSI at the transmitter is not perfect and may include estimation errors. We solve this problem with respect to the Energy Harvesting constraints. We determine the optimal power in the case where the channel is assumed to be perfectly known at the receiver. Also, we obtain the power policy when the transmitter has no CSI. Furthermore, we analyze the asymptotic average throughput in a system where the average recharge rate goes asymptotically to zero and when it is very high.

  20. Study of the Quantum Efficiency of CsI Photocathodes Exposed to Oxygen and Water Vapour

    CERN Document Server

    Di Mauro, A; Piuz, François; Schyns, E M; Van Beelen, J B; Williams, T D

    2000-01-01

    The operation of CsI photocathodes in gaseous detectors requires special attention to the purity of the applied gas mixtures.We have studied the influence of oxygen and water vapour contaminations on the performance of CsI photocathodes for theALICE HMPID RICH prototype. Measurements were done through comparison of Cherenkov rings obtained from beamtests. Increased levels of oxygen and water vapour did not show any effect on the performance. The results of this studyfound a direct application in the way of storing CsI photocathodes over long periods nad in particular in the shipment of theHMPID prototype from CERN to the STAR experiment at BNL. (Abstract only available,full text to follow)

  1. The photoelectric effect from CsI by polarized soft X-rays

    Science.gov (United States)

    Shaw, Ping S.; Church, Eric D.; Hanany, Shaul; Liu, Yee; Fleischman, Judith; Kaaret, Philip; Novick, Robert; Manzo, Giuseppe

    1991-01-01

    Studies of the polarization dependence of the photoelectric effect produced by soft X-rays from CsI indicate that the geometrical effects in these experiments can often mimic the polarization signature. This paper presents a detailed calculation of these geometrical effects that are produced when the X-ray beam is not precisely aligned on a rotatable plane photocathode. The experimentally observed geometrical effects were used to precisely determine the realignment of the incident beam of polarized X-rays on a rotatable photocathode. The results allow determinations of the true polarization dependence of the photoemission from CsI. It is shown that the photoelectric effect in CsI depends on the polarization state of the X-rays.

  2. Clinical-sonographic index (CSI): a novel transcranial Doppler diagnostic model for middle cerebral artery stenosis.

    Science.gov (United States)

    Jung, Keun-Hwa; Lee, Yong-Seok

    2008-07-01

    Transcranial Doppler sonography is useful for the diagnosis of middle cerebral artery (MCA) stenosis. Although the previous studies have focused on the elevated mean flow velocity (MFV) or asymmetry of MFV, the lack of clinical correlation might limit diagnostic accuracy. We try to develop and validate a new diagnostic model including more comprehensive clinical and sonographic parameters. Consecutive patients with magnetic resonance angiography (MRA)-verified MCA stenosis were included, and compared with control subjects with normal MCA. The age, sex, corresponding symptoms (CS) to sonographic side, diabetes mellitus (DM), and hypertension were included for analysis. As sonographic parameters, MFV (cm/sec), asymmetry index (AI,%), and difference of pulsatility index (DeltaPI) were analyzed. Clinical-sonographic index (CSI) model was built with significant parameters by multivariate logistic regression analysis. One hundred and seven patients (M:F = 53:54, age: 61.6 +/- 11.6 years), and 100 control subjects (M:F = 49:51, age: 54.9 +/- 14.5 years) were included. In logistic regression, MFV (odds ratio [OR], 1.057; 95% confidence interval [95% CI], 1.030-1.084), AI (OR, 1.067; 95% CI, 1.031-1.104), DeltaPI (OR, 41.754; 95% CI, 2.771-626.999), CS (OR, 15.904; 95% CI, 5.055-50.042), and DM (OR, 3.949; 95% CI, 1.132-13.783) were independent predictors of MCA stenosis. CSI was simplified for clinical use, CSI = MFV(cm/sec) + 3 * AI (%) + 180 *DeltaPI + 90 * CS(presence = 1, absence = 0) + 30 * DM (presence = 1, absence = 0). The area under the receiver operator characteristic (ROC) curve of MCA stenosis versus MFV, DeltaPI, AI, and CSI was .641, .668, .865 and .953. According to ROC curve, cut-off point for MCA stenosis was suggested as CSI > 180 (sensitivity: 87%, specificity: 92%). CSI might be useful to enhance diagnostic accuracy.

  3. The KiSS1/GPR54 system in fish.

    Science.gov (United States)

    Elizur, Abigail

    2009-01-01

    The KiSS1/GPR54 system has now been identified in non-mammalian vertebrates. Transcripts encoding for KiSS1 and its receptor, GPR54, have been isolated from a number of fish species. The expression of their genes was characterized in the context of temporal and spatial expression and in response to endocrine manipulations. GPR54 sequence is conserved between mammals and fish, with a second receptor sequence identified in zebrafish. The KiSS1 gene sequence is highly divergent between mammals and fish, yet the human kisspeptin is capable of activating the fish GPR54. As in mammals, the fish KiSS1/GPR54 system appears to be partially regulated by gonadal steroids. The data available for fish are fragmented, yet indicate that the KiSS1/GPR54 system is functionally conserved in non-mammalian vertebrates and supports the notion that it has a role in pubertal development and reproduction in piscine systems.

  4. CSI: a nonparametric Bayesian approach to network inference from multiple perturbed time series gene expression data.

    Science.gov (United States)

    Penfold, Christopher A; Shifaz, Ahmed; Brown, Paul E; Nicholson, Ann; Wild, David L

    2015-06-01

    Here we introduce the causal structure identification (CSI) package, a Gaussian process based approach to inferring gene regulatory networks (GRNs) from multiple time series data. The standard CSI approach infers a single GRN via joint learning from multiple time series datasets; the hierarchical approach (HCSI) infers a separate GRN for each dataset, albeit with the networks constrained to favor similar structures, allowing for the identification of context specific networks. The software is implemented in MATLAB and includes a graphical user interface (GUI) for user friendly inference. Finally the GUI can be connected to high performance computer clusters to facilitate analysis of large genomic datasets.

  5. Off-center Tl and Na dopant centers in CsI.

    Science.gov (United States)

    Van Ginhoven, R M; Schultz, P A

    2013-12-11

    We use density functional theory calculations to characterize the electronic and structural properties of the Tl and Na dopant centers in CsI. We find that the Tl and Na centers can accept one or two electrons and couple to long-range relaxations in the surrounding crystal lattice to distort strongly off-center to multiple distinct minima, even without a triplet excitation. The long-range distortions are a mechanism to couple to phonon modes in the crystal, and are expected to play an important role in the phonon-assisted transport of polarons in activated CsI and subsequent light emission in this scintillator.

  6. Expressing human SHOX in Shox2SHOX KI/KI mice leads to congenital osteoarthritis‑like disease of the temporomandibular joint in postnatal mice.

    Science.gov (United States)

    Liang, Wenna; Li, Xihai; Chen, Houhuang; Shao, Xiang; Lin, Xuejuan; Shen, Jianying; Ding, Shanshan; Kang, Jie; Li, Candong

    2016-10-01

    The temporomandibular joint (TMJ), a unique synovial joint whose development differs from that of other synovial joints, develops from two distinct mesenchymal condensations that grow toward each other and ossify through different mechanisms. The short stature homeobox 2 (Shox2) gene serves an important role in TMJ development and previous studies have demonstrated that Shox2SHOX KI/KI mice display a TMJ defective phenotype, congenital dysplasia and premature eroding of the articular disc, which is clinically defined as a TMJ disorder. In the present study, Shox2SHOX KI/KI mouse models were used to investigate the mechanisms of congenital osteoarthritis (OA)‑like disease during postnatal TMJ growth. Shox2SHOX KI/KI mice were observed to develop a severe muscle wasting syndrome from day 7 postnatal. Histological examination indicated that the condyle and glenoid fossa of Shox2SHOX KI/KI mice was reduced in size in the second week after birth. The condyles of Shox2SHOX KI/KI mice exhibited reduced expression levels of collagen type II and Indian hedgehog, and increased expression of collagen type I. A marked increase in matrix metalloproteinase 9 (MMP9) and MMP13 in the condyles was also observed. These cellular and molecular defects may contribute to the observed (OA)‑like phenotype of Shox2SHOX KI/KI mouse TMJs.

  7. In vivo application of sub-second spiral chemical shift imaging (CSI) to hyperpolarized 13C metabolic imaging: comparison with phase-encoded CSI.

    Science.gov (United States)

    Mayer, Dirk; Yen, Yi-Fen; Levin, Yakir S; Tropp, James; Pfefferbaum, Adolf; Hurd, Ralph E; Spielman, Daniel M

    2010-06-01

    A fast spiral chemical shift imaging (CSI) has been developed to address the challenge of the limited acquisition window in hyperpolarized (13)C metabolic imaging. The sequence exploits the sparsity of the spectra and prior knowledge of resonance frequencies to reduce the measurement time by undersampling the data in the spectral domain. As a consequence, multiple reconstructions are necessary for any given data set as only frequency components within a selected bandwidth are reconstructed "in-focus" while components outside that band are severely blurred ("spectral tomosynthesis"). A variable-flip-angle scheme was used for optimal use of the longitudinal magnetization. The sequence was applied to sub-second metabolic imaging of the rat in vivo after injection of hyperpolarized [1-(13)C]-pyruvate on a clinical 3T MR scanner. The comparison with conventional CSI based on phase encoding showed similar signal-to-noise ratio (SNR) and spatial resolution in metabolic maps for the substrate and its metabolic products lactate, alanine, and bicarbonate, despite a 50-fold reduction in scan time for the spiral CSI acquisition. The presented results demonstrate that dramatic reductions in scan time are feasible in hyperpolarized (13)C metabolic imaging without a penalty in SNR or spatial resolution. (c) 2010 Elsevier Inc. All rights reserved.

  8. Lake Nasser evaporation reduction study

    Directory of Open Access Journals (Sweden)

    Hala M.I. Ebaid

    2010-10-01

    Full Text Available This study aims to evaluate the reduction of evaporation of Lake Nasser’s water caused by disconnecting (fully or partially some of its secondary channels (khors. This evaluation integrates remote sensing, Geographic Information System (GIS techniques, aerodynamic principles, and Landsat7 ETM+ images. Three main procedures were carried out in this study; the first derived the surface temperature from Landsat thermal band; the second derived evaporation depth and approximate evaporation volume for the entire lake, and quantified evaporation loss to the secondary channels’ level over one month (March by applied aerodynamic principles on surface temperature of the raster data; the third procedure applied GIS suitability analysis to determine which of these secondary channels (khors should be disconnected. The results showed evaporation depth ranging from 2.73 mm/day at the middle of the lake to 9.58 mm/day at the edge. The evaporated water-loss value throughout the entire lake was about 0.86 billion m3/month (March. The analysis suggests that it is possible to save an approximate total evaporation volume loss of 19.7 million m3/month (March, and thus 2.4 billion m3/year, by disconnecting two khors with approximate construction heights of 8 m and 15 m. In conclusion, remote sensing and GIS are useful for applications in remote locations where field-based information is not readily available and thus recommended for decision makers remotely planning in water conservation and management.

  9. Roles of Ki67 in Breast Cancer - Important for Management?

    Science.gov (United States)

    Yip, Ch; Bhoo-Pathy, N; Daniel, Jm; Foo, Yc; Mohamed, Ak; Abdullah, Mm; Ng, Ys; Yap, Bk; Pathmanathan, R

    2016-01-01

    The three standard biomarkers used in breast cancer are the estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2). The Ki-67 index, a proliferative marker, has been shown to be associated with a poorer outcome, and despite absence of standardization of pathological assessment, is widely used for therapy decision making. We aim to study the role of the Ki-67 index in a group of Asian women with breast cancer. A total of 450 women newly diagnosed with Stage 1 to 3 invasive breast cancer in a single centre from July 2013 to Dec 2014 were included in this study. Univariable and multivariable logistic regression was used to determine the association between Ki-67 (positive defined as 14% and above) and age, ethnicity, grade, mitotic index, ER, PR, HER2, lymph node status and size. All analyses were performed using SPSS Version 22. In univariable analysis, Ki -67 index was associated with younger age, higher grade, ER and PR negativity, HER2 positivity, high mitotic index and positive lymph nodes. However on multivariable analysis only tumour size, grade, PR and HER2 remained significant. Out of 102 stage 1 patients who had ER positive/PR positive/HER2 negative tumours and non-grade 3, only 5 (4.9%) had a positive Ki-67 index and may have been offered chemotherapy. However, it is interesting to note that none of these patients received chemotherapy. Information on Ki67 would have potentially changed management in an insignificant proportion of patients with stage 1 breast cancer.

  10. Logistički informacioni sistem / Logistics information system

    OpenAIRE

    Marko D. Andrejić; Marjan A. Milenkov; Vlada S. Sokolović

    2010-01-01

    Logistički automatizovani informacioni sistem treba razvijati kao deo jedinstvenog automatizovanog informacionog sistema (JAIS-a). Da bi se logistički automatizovani informacioni sistem uspešno razvijao i primenjivao u operativnoj praksi, neophodno je slediti globalni koncept razvoja JAIS-a i u razvoju više primenjivati timski rad profesionalnog informatičara i poznavaoca realnog logističkog sistema. Bitan uslov za razvoj kvalitetnog logističkog informacionog sistema jeste definisanje informa...

  11. NAUTIČKI TURIZAM – DEFINICIJE I DILEME

    OpenAIRE

    Luković, Tihomir

    2007-01-01

    Nautički turizam fenomen je koji je u protekla tri desetljeća zabilježio jednu od najviših razvojnih stopa poznatih u europskom i hrvatskom gospodarstvu. Ekonomski prognostičari razvoja turizma slažu se da se nautički turizam nalazi u početnom razvojnom razdoblju i da se visoki rezultati tek očekivaju. Razvoj nautičkog turizma sa znanstvenog aspekta nedostatno je zastupljen u turističkoj znanosti. Za Hrvatsku to je nova gospodarska razvojna šansa, što je potaknulo sve življu znanstvenu i istr...

  12. DTM determination within Kurozwęki project

    OpenAIRE

    Aleksandar; Stefan; Miroslav; Sara

    2014-01-01

    The project in Kurozwęki, small historical city near Krakow, is a project with a tradition. It is held last ten years with a same reason. The main idea of the Mr. Martin Popiel, who is the owner of Palace in Kurozwęki, is to include students and youth in upgrading of his castle. He invites a small group of students from different universities to a ten days long camp, to hear and discuss their ideas. That brings a benefit to both sides because students have a new experience behind them after t...

  13. Pressure dependence of structural phase transition and superconducting transition in CsI

    CERN Document Server

    Nirmala-Louis, C

    2003-01-01

    The self-consistent band structure calculation for CsI performed both in CsCl and HCP structures using the TB-LMTO method is reported. The equilibrium lattice constant, bulk modulus and the phase-transition pressure at which the compound undergoes structural phase transition from CsCl to HCP are predicted from the total-energy calculations. The band structure, density of states (DOS), electronic charge distributions, metallization and superconducting transition temperature (T sub c) of CsI are obtained as a function of pressure for both the CsCl and HCP structures. It is found that the charge transfer from s and p states to d state causes metallization and superconductivity in CsI. The highest T sub c estimated is 2.11 K and the corresponding pressure is 1.8 Mbar. This value is in agreement with the recent experimental observation. The experimental trend - ''metallization and superconductivity is rather insensitive to the crystal structure of CsI'' - is also confirmed in our work. (Abstract Copyright [2003], ...

  14. Distributed cognitive two-way relay beamformer designs under perfect and imperfect CSI

    KAUST Repository

    Pandarakkottilil, Ubaidulla

    2011-09-01

    In this paper, we present distributed two-way relay beamformer designs for a cognitive radio network (CRN) in which a pair of cognitive (or secondary) transceiver nodes communicate with each other assisted by a set of cognitive two-way relay nodes. The secondary nodes share the spectrum with a licensed primary user (PU) node, and each node is assumed to be equipped with a single transmit/receive antenna. The interference to the PU resulting from the transmission from the cognitive nodes is kept below a specified limit. First, we consider relay beamformer designs assuming the availability of perfect channel state information (CSI). For this case, a mean-square error (MSE)-constrained beamformer that minimizes the total relay transmit power, and an MSE-balancing beamformer with a constraint on the total relay transmit power are proposed. Next, we consider relay beamformer designs assuming that the available CSI is imperfect. For this case too, we consider the same problems as those in the case of perfect CSI, and propose beamformer designs that are robust to the errors in the CSI. We show that the proposed designs can be reformulated as convex optimization problems that can be solved efficiently. Through numerical simulations, we illustrate the performance of the proposed designs. © 2011 IEEE.

  15. Decoupled front/back dielectric textures for flat ultra-thin c-Si solar cells

    NARCIS (Netherlands)

    Isabella, O.; Vismara, R.; Ingenito, A.; Rezaei, N.; Zeman, M.

    2016-01-01

    The optical analysis of optically-textured and electrically-flat ultra-thin crystalline silicon (c-Si) slabs is presented. These slabs were endowed with decoupled front titanium-dioxide (TiO2) / back silicon-dioxide (SiO2) dielectric textures and were studied as function of two types of back

  16. Iterative Equalization and Interference Alignment for Multiuser MIMO HetNets with Imperfect CSI

    Directory of Open Access Journals (Sweden)

    Daniel Castanheira

    2015-01-01

    Full Text Available In this paper we consider a scenario, where several small-cells work under the same coverage area and spectrum of a macrocell. The signals stemming from the small-cell (macrocell users if not carefully dealt with will generate harmful interference into the macrocell (small-cell. To tackle this problem interference alignment and iterative equalization techniques are considered. By using IA all interference generated by the small-cell (macrocell users is aligned along a low dimensional subspace, at the macrocell (small-cells. This reduces considerably the amount of resources allocated, to enable the coexistence of the two systems. However, perfect IA requires the availability of error-free channel state information (CSI at the transmitters. Due to CSI errors one can have substantial performance degradation due to imperfect alignments. Since in this work the IA precoders are based on imperfect CSI, an efficient iterative space-frequency equalization is designed at the receiver side to cope with the residual aligned interference. The results demonstrate that iterative equalization is robust to imperfect CSI and removes efficiently the interference generated by the poorly aligned interference. Close to matched filter bound performance is achieved, with a very few number of iterations.

  17. Sequential C-Si Bond Formations from Diphenylsilane: Application to Silanediol Peptide Isostere Precursors

    DEFF Research Database (Denmark)

    Nielsen, Lone; Skrydstrup, Troels

    2008-01-01

    and the first new carbon-silicon bond. The next step is the reduction of this hydridosilane with lithium metal providing a silyl lithium reagent, which undergoes a highly diastereoselective addition to an optically active tert-butanesulfinimine, thus generating the second C-Si bond. This method allows...

  18. CSI Web Adventures: A Forensics Virtual Apprenticeship for Teaching Science and Inspiring STEM Careers

    Science.gov (United States)

    Miller, Leslie; Chang, Ching-I; Hoyt, Daniel

    2010-01-01

    CSI: The Experience, a traveling museum exhibit and a companion web adventure, was created through a grant from the National Science Foundation as a potential model for informal learning. The website was designed to enrich and complement the exhibit by modeling the forensic process. Substantive science, real-world lab techniques, and higher-level…

  19. FleCSPH - a parallel and distributed SPH implementation based on the FleCSI framework

    Energy Technology Data Exchange (ETDEWEB)

    2017-06-20

    FleCSPH is a multi-physics compact application that exercises FleCSI parallel data structures for tree-based particle methods. In particular, FleCSPH implements a smoothed-particle hydrodynamics (SPH) solver for the solution of Lagrangian problems in astrophysics and cosmology. FleCSPH includes support for gravitational forces using the fast multipole method (FMM).

  20. Effects of Erroneous CSI on the Performance of Multiple-Transmit Antenna Selection

    Directory of Open Access Journals (Sweden)

    Mingjie Zhuang

    2015-01-01

    Full Text Available The paper assumes that the channel state information (CSI is available at the receiver and is known partially at the transmitter through a feedback channel. The bit error rate (BER performance of multiple transmit antenna selection (MTAS for the multiple-input and single-output (MISO system with STBC (MTAS/MISO-STBC will be investigated in detail. Meanwhile, the selection criterion that maximizes the channel Frobenius norm or minimizes the error probability of MTAS/MISO-STBC system is employed. In two cases of erroneous CSI (ECSI and inerrable CSI (ICSI, wireless channels of the MTAS systems are modeled and their analytical expressions are derived. For the case of ICSI, the exact BER expressions of the Chernoff upper bound (CUB for both the MISO-STBC system of full complexity and MTAS system are evaluated, respectively. Next, for the ECSI case, a comprehensive analytical expression of BER CUB for the same system is derived in detail. Finally, extensive Monte-Carlo simulations are presented to support and validate our numerical analysis proposed in this paper. Both the simulating results and the numerical results show that MTAS can reduce effectively the effect of the erroneous CSI.

  1. Achievable Rates of Cognitive Radio Networks Using Multi-Layer Coding with Limited CSI

    KAUST Repository

    Sboui, Lokman

    2016-03-01

    In a Cognitive Radio (CR) framework, the channel state information (CSI) feedback to the secondary transmitter (SU Tx) can be limited or unavailable. Thus, the statistical model is adopted in order to determine the system performance using the outage concept. In this paper, we adopt a new approach using multi-layer-coding (MLC) strategy, i.e., broadcast approach, to enhance spectrum sharing over fading channels. First, we consider a scenario where the secondary transmitter has no CSI of both the link between SU Tx and the primary receiver (cross-link) and its own link. We show that using MLC improves the cognitive rate compared to the rate provided by a singlelayer- coding (SLC). In addition, we observe numerically that 2-Layer coding achieves most of the gain for Rayleigh fading. Second, we analyze a scenario where SU Tx is provided by partial CSI about its link through quantized CSI. We compute its achievable rate adopting the MLC and highlight the improvement over SLC. Finally, we study the case in which the cross-link is perfect, i.e., a cooperative primary user setting, and compare the performance with the previous cases. We present asymptotic analysis at high power regime and show that the cooperation enhances considerably the cognitive rate at high values of the secondary power budget.

  2. CSI-EPT in Presence of RF-Shield for MR-Coils.

    Science.gov (United States)

    Arduino, Alessandro; Zilberti, Luca; Chiampi, Mario; Bottauscio, Oriano

    2017-07-01

    Contrast source inversion electric properties tomography (CSI-EPT) is a recently developed technique for the electric properties tomography that recovers the electric properties distribution starting from measurements performed by magnetic resonance imaging scanners. This method is an optimal control approach based on the contrast source inversion technique, which distinguishes itself from other electric properties tomography techniques for its capability to recover also the local specific absorption rate distribution, essential for online dosimetry. Up to now, CSI-EPT has only been described in terms of integral equations, limiting its applicability to homogeneous unbounded background. In order to extend the method to the presence of a shield in the domain-as in the recurring case of shielded radio frequency coils-a more general formulation of CSI-EPT, based on a functional viewpoint, is introduced here. Two different implementations of CSI-EPT are proposed for a 2-D transverse magnetic model problem, one dealing with an unbounded domain and one considering the presence of a perfectly conductive shield. The two implementations are applied on the same virtual measurements obtained by numerically simulating a shielded radio frequency coil. The results are compared in terms of both electric properties recovery and local specific absorption rate estimate, in order to investigate the requirement of an accurate modeling of the underlying physical problem.

  3. A commutation strategy for IGBT-based CSI-fed parallel resonant ...

    Indian Academy of Sciences (India)

    A brief study on a commutation strategy for a current source inverter (CSI)-fed parallel resonant circuit, using switches formed by IGBTs with series diodes, is presented in this paper. The dynamic behaviour of the inverter and different strategies for its reliable operation are discussed here considering parasitic inductance ...

  4. Non-Cartesian Parallel Imaging Reconstruction of Undersampled IDEAL Spiral 13C CSI Data

    DEFF Research Database (Denmark)

    Hansen, Rie Beck; Hanson, Lars G.; Ardenkjær-Larsen, Jan Henrik

    scan times based on spatial information inherent to each coil element. In this work, we explored the combination of non-cartesian parallel imaging reconstruction and spatially undersampled IDEAL spiral CSI1 acquisition for efficient encoding of multiple chemical shifts within a large FOV with high...

  5. Application of compressed sensing to in vivo 3D ¹⁹F CSI.

    Science.gov (United States)

    Kampf, T; Fischer, A; Basse-Lüsebrink, T C; Ladewig, G; Breuer, F; Stoll, G; Jakob, P M; Bauer, W R

    2010-12-01

    This study shows how applying compressed sensing (CS) to (19)F chemical shift imaging (CSI) makes highly accurate and reproducible reconstructions from undersampled datasets possible. The missing background signal in (19)F CSI provides the required sparsity needed for application of CS. Simulations were performed to test the influence of different CS-related parameters on reconstruction quality. To test the proposed method on a realistic signal distribution, the simulation results were validated by ex vivo experiments. Additionally, undersampled in vivo 3D CSI mouse datasets were successfully reconstructed using CS. The study results suggest that CS can be used to accurately and reproducibly reconstruct undersampled (19)F spectroscopic datasets. Thus, the scanning time of in vivo(19)F CSI experiments can be significantly reduced while preserving the ability to distinguish between different (19)F markers. The gain in scan time provides high flexibility in adjusting measurement parameters. These features make this technique a useful tool for multiple biological and medical applications. Copyright © 2010 Elsevier Inc. All rights reserved.

  6. The CSI Academy: Encouraging Diverse Students to Consider Science Careers and Science Teaching

    Science.gov (United States)

    Kaye, Karen; Turner, John F.; Emigh, James

    2011-01-01

    The CSI academies employed a multi-layered, collaborative approach to encourage diverse students to consider STEM careers, including science teaching. The academies recruited a diverse group of high school students. This was due, in large part, to the creation of a unique selection process that identified students with unrealized potential. The…

  7. Children and Crime Scenes: Have Schools Fallen Victim to the CSI Effect?

    Science.gov (United States)

    Eskriett, Angela

    2011-01-01

    Whilst there continues to be debate regarding the influence of the "CSI effect" upon the criminal justice system, there appears to be a general consensus that the popularisation of work within the field, particularly through a number of "procedural cop shows", has fuelled an explosion in the number of young people choosing to pursue a career in…

  8. Detection of Potential Induced Degradation in c-Si PV Panels Using Electrical Impedance Spectroscopy

    DEFF Research Database (Denmark)

    Oprea, Matei-lon; Spataru, Sergiu; Sera, Dezso

    2016-01-01

    ) in c-Si PV panels. The method has been experimentally tested using an automated PID test bed, and the IS results were confirmed using traditional current-voltage characterization methods, as well as electroluminescence imaging. The corroborated results confirm the effectiveness of the new approach...

  9. Detection of Potential Induced Degradation in c-Si PV Panels Using Electrical Impedance Spectroscopy

    DEFF Research Database (Denmark)

    Oprea, Matei-lon; Spataru, Sergiu; Sera, Dezso

    This work, for the first time, investigates an Impedance Spectroscopy (IS) based method for detecting potential-induced degradation (PID) in crystalline silicon photovoltaic (c-Si PV) panels. The method has been experimentally tested on a set of panels that were confirmed to be affected by PID...

  10. Exploring K-3 Teachers' Implementation of Comprehension Strategy Instruction (CSI) Using Expectancy-Value Theory

    Science.gov (United States)

    Foley, Laura S.

    2011-01-01

    This research investigated factors that influence the implementation levels of evidence-based comprehension strategy instruction (CSI) among K-3 teachers. An explanatory design was chosen to gather and probe the data. Quantitative data were gathered via a mailed survey distributed through a representative sample of the 40 school districts (through…

  11. Cooling clothing utilizing water evaporation

    DEFF Research Database (Denmark)

    Sakoi, Tomonori; Tominaga, Naoto; Melikov, Arsen Krikor

    2014-01-01

    We developed cooling clothing that utilizes water evaporation to cool the human body and has a mechanism to control the cooling intensity. Clean water was supplied to the outer surface of the T-shirt of the cooling clothing, and a small fan was used to enhance evaporation on this outer surface....... To prevent wet discomfort, the T-shirt was made of a polyester material having a water-repellent silicon coating on the inner surface. The chest, front upper arms, and nape of the neck were adopted as the cooling areas of the human body. We conducted human subject experiments in an office with air...... temperature ranging from 27.4 to 30.7 °C to establish a suitable water supply control method. A water supply control method that prevents water accumulation in the T-shirt and water dribbling was validated; this method is established based on the concept of the water evaporation capacity under the applied...

  12. Tubular sublimatory evaporator heat sink

    Science.gov (United States)

    Webbon, B. W. (Inventor)

    1977-01-01

    An evaporative refrigerator or cooler comprising a bundle of spaced, porous walled tubes closed at one of their ends and vented to a vacuum at the other end is disclosed. The tube bundle is surrounded by a water jacket having a hot water inlet distribution manifold and a cooled water outlet through a plenum chamber. Hot water is pumped into the jacket to circulate around the tubes, and when this water meets the vacuum existing inside the tubes, it evaporates thereby cooling the water in the jacket. If cooling proceeds to the point where water penetrating or surrounding all or part of the tubes freezes, operation continues with local sublimation of the ice on the tubes while the circulating water attempts to melt the ice. Both sublimation and evaporation may take place simultaneously in different regions of the device.

  13. Water Evaporation in Swimming Baths

    DEFF Research Database (Denmark)

    Hyldgård, Carl-Erik

    This paper is publishing measuring results from models and full-scale baths of the evaporation in swimming baths, both public baths and retraining baths. Moreover, the heat balance of the basin water is measured. In addition the full-scale measurements have given many experiences which are repres......This paper is publishing measuring results from models and full-scale baths of the evaporation in swimming baths, both public baths and retraining baths. Moreover, the heat balance of the basin water is measured. In addition the full-scale measurements have given many experiences which...

  14. Energy storage in evaporated brine

    Energy Technology Data Exchange (ETDEWEB)

    MacDonald, R. Ian

    2010-09-15

    We propose storage of electrical energy in brine solutions by using the energy to enhance natural evaporation. Using properties of existing industrial evaporation technologies and estimates of power regeneration from brine by pressure retarded osmosis, efficiency near 100% is calculated. Modelling indicates that systems ranging from 50kW to 50MW output may be practical, with storage capacities of hours to days. The method appears to have potential to be economically competitive with other technologies over a wide range of capacity. It may present a large new application area that could aid the development of salinity-based power generation technology.

  15. modeling of evaporation modeling of evaporation losses in sewage

    African Journals Online (AJOL)

    eobe

    advance treatment. This shall be the task of sludge drying process, understood as thermal drying process in which thermal energy is delivered to the sludge in order to evaporate water [5].The exchange of mass and heat between dried sludge and air (material and. Nigerian Journal of Technology (NIJOTECH). Vol. 34 No.

  16. see Solanki GK 813 Ahn Choon Ki Robust chaos synchronization ...

    Indian Academy of Sciences (India)

    Adegoke Kunle. Continuous quantum phase transitions in the one-dimensional spin-1/2 axial next- nearest-neighbour Ising model in two or- thogonal magnetic fields. 293. Agarwal M K see Solanki G K. 813. Ahn Choon Ki. Robust chaos synchronization using input-to-state stable control. 705. Ahuja B L see Dashora Alpa.

  17. KiT: a MATLAB package for kinetochore tracking.

    Science.gov (United States)

    Armond, Jonathan W; Vladimirou, Elina; McAinsh, Andrew D; Burroughs, Nigel J

    2016-06-15

    During mitosis, chromosomes are attached to the mitotic spindle via large protein complexes called kinetochores. The motion of kinetochores throughout mitosis is intricate and automated quantitative tracking of their motion has already revealed many surprising facets of their behaviour. Here, we present 'KiT' (Kinetochore Tracking)-an easy-to-use, open-source software package for tracking kinetochores from live-cell fluorescent movies. KiT supports 2D, 3D and multi-colour movies, quantification of fluorescence, integrated deconvolution, parallel execution and multiple algorithms for particle localization. KiT is free, open-source software implemented in MATLAB and runs on all MATLAB supported platforms. KiT can be downloaded as a package from http://www.mechanochemistry.org/mcainsh/software.php The source repository is available at https://bitbucket.org/jarmond/kit and under continuing development. Supplementary data are available at Bioinformatics online. jonathan.armond@warwick.ac.uk. © The Author 2016. Published by Oxford University Press.

  18. Coenite seiklused ja Kim Ki-duki huumor / Merit Kask

    Index Scriptorium Estoniae

    Kask, Merit

    2007-01-01

    60-nda Cannes'i filmifestivali filme : Ethan ja Joel Coen'i "Pole maad vanadele meestele" ("No Country for Old Men" ; Ameerika Ühendriigid), Kim Ki-duki "Hingetõmme" ("Soom"/"Breath" ; Lõuna-Korea) ja Raphael Nadjari "Tehilim" (Prantsusmaa - Iisrael - Ameerika Ühendriigid)

  19. Prikljutshenija Koenov i jumor Kim Ki-duka / Merit Kask

    Index Scriptorium Estoniae

    Kask, Merit

    2007-01-01

    60-nda Cannes'i filmifestivali filme : Ethan ja Joel Coen'i "Pole maad vanadele meestele" ("No Country for Old Men" ; Ameerika Ühendriigid), Kim Ki-duki "Hingetõmme" ("Soom"/"Breath" ; Lõuna-Korea) ja Raphael Nadjari "Tehilim" (Prantsusmaa - Iisrael - Ameerika Ühendriigid)

  20. Statistical Inconsistencies in the KiDS-450 Dataset

    Science.gov (United States)

    Efstathiou, George; Lemos, Pablo

    2018-01-01

    The Kilo-Degree Survey (KiDS) has been used in several recent papers to infer constraints on the amplitude of the matter power spectrum and matter density at low redshift. Some of these analyses have claimed tension with the Planck ΛCDM cosmology at the ˜2 - 3σ level, perhaps indicative of new physics. However, Planck is consistent with other low redshift probes of the matter power spectrum such as redshift space distortions and the combined galaxy-mass and galaxy-galaxy power spectra. Here we perform consistency tests of the KiDS data, finding internal tensions for various cuts of the data at ˜2.2 - 3.5σ significance. Until these internal tensions are understood, we argue that it is premature to claim evidence for new physics from KiDS. We review the consistency between KiDS and other weak lensing measurements of S8, highlighting the importance of intrinsic alignments for precision cosmology.

  1. Preparation and characterization of PAN–KI complexed gel polymer ...

    Indian Academy of Sciences (India)

    The free standing and dimensionally stable gel polymer electrolyte films of polyacrylonitrile (PAN): potassium iodide (KI) of different compositions, using ethylene carbonate as a plasticizer and dimethyl formamide as solvent, are prepared by adopting 'solution casting technique' and these films are examined for their ...

  2. CSI: a severity index for Clostridium difficile infection at the time of admission.

    Science.gov (United States)

    Lungulescu, O A; Cao, W; Gatskevich, E; Tlhabano, L; Stratidis, J G

    2011-10-01

    Clostridium difficile is a common cause of nosocomial diarrhoea in the USA. To develop a score model that would help to identify severe versus mild or moderate C. difficile infection (CDI) upon admission we performed a retrospective cohort study. Between January 2004 and December 2007, 255 patients met inclusion criteria for this study. Severe CDI was defined as cases that required colectomy, intensive care unit management, ended in death, or hospitalisation of >10 days. Data recorded included past medical history, physical examination on admission, laboratory data and imaging/colonoscopy data. To create the CDI severity index (CSI) score, we included four risk factors for severe CDI that were identified by univariate analysis: history of malignancy, white blood cell count at admission >20,000/dL, blood albumin 1.5-fold the baseline value. One point was assigned to each of the risk factors. As indicated by a c-statistic of 0.78, the CSI score predicted severe CDI much better than chance (c-statistics of 0.50). The risk of developing severe CDI increased by a factor of 2.9 (95% CI: 1.82-4.59) for each 1-point increase in the CSI score. A CSI score with a cut-off value of 2 had a sensitivity and specificity of 82% and 65%, respectively. The CSI score may quantify the risk of severe CDI at the time of admission, and help in early identification of patients who may benefit from more aggressive treatment. Copyright © 2011 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

  3. The sustainability of LNG evaporation

    NARCIS (Netherlands)

    Stougie, L.; Van der Kooi, H.J.

    2011-01-01

    Numerous LNG (Liquefied Natural Gas) import terminals are under construction to fulfil the growing demand for energy carriers. After storage in tanks, the LNG needs to be heated and evaporated, also called ‘regasified’, to the natural gas needed in households and industry. Several options exist for

  4. [Measurement of socioeconomic status in the KiGGS study: first follow-up (KiGGS Wave 1)].

    Science.gov (United States)

    Lampert, Thomas; Müters, S; Stolzenberg, H; Kroll, L E

    2014-07-01

    This article describes the measurement of socioeconomic status in the first follow-up of the KiGGS study (KiGGS Wave 1) conducted from 2009 to 2012. A multidimensional index score was used. The score is the sum of three metric components: Education and Occupational Qualification, Occupational Status, and Net Income. Compared with the approach in the KiGGS baseline study, some modifications were made in accordance with changes in the other components of the health-monitoring program at the Robert Koch Institute, i.e., the German Health Update (GEDA) and the German Health Interview and Examination Survey for Adults (DEGS1). These changes facilitate the analysis of temporal developments and trends, ensure international comparability of the data, and support the transfer of the results into politics and practice. In order to demonstrate the application of the revised instrument, we report on exemplary results of KiGGS Wave 1 regarding the relationship between socioeconomic status and the general health status of children and adolescents aged 3-17 years.

  5. Light yield of an undoped CsI crystal coupled directly to a photomultiplier tube at 77 Kelvin

    OpenAIRE

    Liu, Jing; Yamashita, Masaki; Soma, Arun Kumar

    2016-01-01

    A light yield of 20.4 $\\pm$ 0.8 photoelectrons/keV was achieved with an undoped CsI crystal coupled directly to a photomultiplier tube at 77 Kelvin. This is by far the largest yield in the world achieved with CsI crystals. An energy threshold that is several times lower than the current dark matter experiments utilizing CsI(Tl) crystals may be achievable using this technique. Together with novel CsI crystal purification methods, the technique may be used to improve the sensitivities of dark m...

  6. Quantifying Evaporation in a Permeable Pavement System

    Science.gov (United States)

    Studies quantifying evaporation from permeable pavement systems are limited to a few laboratory studies and one field application. This research quantifies evaporation for a larger-scale field application by measuring the water balance from lined permeable pavement sections. Th...

  7. Modelling refrigerant distribution in microchannel evaporators

    DEFF Research Database (Denmark)

    Brix, Wiebke; Kærn, Martin Ryhl; Elmegaard, Brian

    2009-01-01

    The effects of refrigerant maldistribution in parallel evaporator channels on the heat exchanger performance are investigated numerically. For this purpose a 1D steady state model of refrigerant R134a evaporating in a microchannel tube is built and validated against other evaporator models. A stu...... out of the evaporator is kept constant. It is shown that the cooling capacity of the evaporator is reduced significantly, both in the case of unevenly distributed inlet quality and for the case of non-uniform airflow on the outside of the channels.......The effects of refrigerant maldistribution in parallel evaporator channels on the heat exchanger performance are investigated numerically. For this purpose a 1D steady state model of refrigerant R134a evaporating in a microchannel tube is built and validated against other evaporator models. A study...

  8. Body and Ki in Gicheon : practices of self-cultivation in contemporary Korea

    NARCIS (Netherlands)

    Jeon, Y.

    2017-01-01

    In this dissertation I study the social phenomenon of ki suryŏn (ki-training) as an invented tradition and examine how it functions within Korean society. Mind-body practices referred to as qigong in China and ki suryŏn in Korea are re-constructed in modernity on the basis of ancient East-Asian

  9. Astro-WISE for KiDS survey production and quality control

    NARCIS (Netherlands)

    Kleijn, G.V.; de Jong, Jelte; Valentijn, E.; Kuijken, K.; Consortiums, KiDS; Consortium, Astro-WISE; Ballester, P.; Egret, D.; Lorente, N.P.F.

    The Kilo Degree Survey (KiDS) is a 1500 square degree optical imaging survey with the recently commissioned OmegaCAM wide-field imager on the VLT Survey Telescope (VST). A suite of data products will be delivered to ESO and the community by the KiDS survey team. Spread over Europe, the KiDS team

  10. A surfeit of science: The "CSI effect" and the media appropriation of the public understanding of science.

    Science.gov (United States)

    Cole, Simon A

    2015-02-01

    Over the past decade, popular media has promulgated claims that the television program CSI and its spinoffs and imitators have had a pernicious effect on the public understanding of forensic science, the so-called "CSI effect." This paper analyzes those media claims by documenting the ways in which the media claims that CSI "distorts" an imagined "reality." It shows that the media appropriated the analytic stance usually adopted by science advocates, portraying the CSI effect as a social problem in science communication. This appropriation was idiosyncratic in that it posited, as a social problem, a "surfeit" of knowledge and positive imagery about science, rather than the more familiar "deficits." In addition, the media simultaneously appropriated both "traditional" and "critical" PUS discourses. Despite this apparent contradiction, the paper concludes that, in both discourses, the media and its expert informants insist upon their hegemony over "the public" to articulate the "reality" of forensic science. © The Author(s) 2013.

  11. Multifractal property of Chinese stock market in the CSI 800 index based on MF-DFA approach

    Science.gov (United States)

    Zhu, Huijian; Zhang, Weiguo

    2018-01-01

    CSI 800 index consists of CSI 500 index and CSI 300 index, aiming to reflect the performance of stocks with large, mid and small size of China A share market. In this paper we analyze the multifractal structure of Chinese stock market in the CSI 800 index based on the multifractal detrended fluctuation analysis (MF-DFA) method. We find that the fluctuation of the closing logarithmic returns have multifractal properties, the shape and width of multifractal spectrum are depended on the weighing order q. More interestingly, we observe a bigger market crash in June-August 2015 than the one in 2008 based on the local Hurst exponents. The result provides important information for further study on dynamic mechanism of return fluctuation and whether it would trigger a new financial crisis.

  12. Evaporation from a sphagnum moss surface

    Science.gov (United States)

    D.S. Nichols; J.M. Brown

    1980-01-01

    Peat cores, 45 cm in diameter, were collected from a sphagnum bog in northern Minnesota, and used to measure the effects of different temperatures and water levels on evaporation from a sphagnum moss surface in a growth chamber. Under all conditions, evaporation from the moss surface was greater than that from a free-water surface. Evaporation from the moss increased...

  13. Iodine retention during evaporative volume reduction

    Science.gov (United States)

    Godbee, H.W.; Cathers, G.I.; Blanco, R.E.

    1975-11-18

    An improved method for retaining radioactive iodine in aqueous waste solutions during volume reduction is disclosed. The method applies to evaporative volume reduction processes whereby the decontaminated (evaporated) water can be returned safely to the environment. The method generally comprises isotopically diluting the waste solution with a nonradioactive iodide and maintaining the solution at a high pH during evaporation.

  14. PSIHOLOŠKI VIDIKI BARV PRI IZDELAVI LOGOTIPA

    OpenAIRE

    Bauman, Anja

    2015-01-01

    Osrednja tema diplomske naloge so psihološki vidiki barv pri izdelavi logotipa. Diplomska naloga zajema tako teoretični kot tudi empirični del. V teoretičnem delu je predstavljen logotip in njegovi kriteriji uspešnosti. Prav tako pa so predstavljene tudi barve, njeni učinki ter značilnosti. Empirični del diplomske naloge pa se ukvarja z analizo obstoječih in izdelanih logotipov.

  15. Multiplexed CRISPR/Cas9 Genome Editing and Gene Regulation Using Csy4 in Saccharomyces cerevisiae.

    Science.gov (United States)

    Ferreira, Raphael; Skrekas, Christos; Nielsen, Jens; David, Florian

    2018-01-19

    Clustered regularly interspaced short palindromic repeats (CRISPR) technology has greatly accelerated the field of strain engineering. However, insufficient efforts have been made toward developing robust multiplexing tools in Saccharomyces cerevisiae. Here, we exploit the RNA processing capacity of the bacterial endoribonuclease Csy4 from Pseudomonas aeruginosa, to generate multiple gRNAs from a single transcript for genome editing and gene interference applications in S. cerevisiae. In regards to genome editing, we performed a quadruple deletion of FAA1, FAA4, POX1 and TES1 reaching 96% efficiency out of 24 colonies tested. Then, we used this system to efficiently transcriptionally regulate the three genes, OLE1, HMG1 and ACS1. Thus, we demonstrate that multiplexed genome editing and gene regulation can be performed in a fast and effective manner using Csy4.

  16. Outage Performance of Decode-and-Forward in Two-Way Relaying with Outdated CSI

    KAUST Repository

    Hyadi, Amal

    2015-01-07

    In this paper, we analyze the outage behavior of decode-and-forward relaying in the context of selective two-way cooperative systems. First, a new relay selection metric is proposed to take into consideration both transmission rates and instantaneous link conditions between cooperating nodes. Afterwards, the outage probability of the proposed system is derived for Nakagami-m fading channels in the case when perfect channel state information is available and then extended to the more realistic scenario where the available channel state information (CSI) is outdated due to fast fading. New expressions for the outage probability are obtained, and the impact of imperfect CSI on the performance is evaluated. Illustrative numerical results, Monte Carlo simulations, and comparisons with similar approaches are presented to assess the accuracy of our analytical derivations and confirm the performance gain of the proposed scheme.

  17. Optimization of laser fired contact processes in c-Si solar cells

    Science.gov (United States)

    Sánchez-Aniorte, I.; Colina, M.; Perales, F.; Molpeceres, C.

    In this work, we study the optimization of aluminium laser-fired contacts (LFC) [1] in combination with c-Si passivated solar cell [2,3]. The samples consist in p-type Fz c-Si wafers with two different passivating configurations; both thermally-grown silicon oxide (SiO2) and plasma deposited silicon carbide (SiCx) were used as the passivating rear layer. Finally, a 2 μ m Aluminum layer was deposited at the front and rear surface. A nanosecond Nd:YAG laser operating at 532 nm was used to fire the aluminum locally through the thin passivating layer. Green lasers offer the possibility to obtain a selective removal of the passivating layer, since the underlying silicon results typically less affected than when using IR radiation. Morphological and electrical analysis permitted to identify the optimal laser parameters to achieve good ohmic contacts and to reduce the laser-damaged area.

  18. A copula-multifractal volatility hedging model for CSI 300 index futures

    Science.gov (United States)

    Wei, Yu; Wang, Yudong; Huang, Dengshi

    2011-11-01

    In this paper, we propose a new hedging model combining the newly introduced multifractal volatility (MFV) model and the dynamic copula functions. Using high-frequency intraday quotes of the spot Shanghai Stock Exchange Composite Index (SSEC), spot China Securities Index 300 (CSI 300), and CSI 300 index futures, we compare the direct and cross hedging effectiveness of the copula-MFV model with several popular copula-GARCH models. The main empirical results show that the proposed copula-MFV model obtains better hedging effectiveness than the copula-GARCH-type models in general. Furthermore, the hedge operating strategy based MFV hedging model involves fewer transaction costs than those based on the GARCH-type models. The finding of this paper indicates that multifractal analysis may offer a new way of quantitative hedging model design using financial futures.

  19. Behind the Nature of Titanium Oxide Excellent Surface Passivation and Carrier Selectivity of c-Si

    DEFF Research Database (Denmark)

    Plakhotnyuk, Maksym; Crovetto, Andrea; Hansen, Ole

    We present an expanded study of the passivation properties of titanium dioxide (TiO2) on p-type crystalline silicon (c-Si). We report a low surface recombination velocity (16 cm/s) for TiO2 passivation layers with a thin tunnelling oxide interlayer (SiO2 or Al2O3) on p-type crystalline silicon (c......-Si). The TiO2 films were deposited by thermal atomic layer deposition (ALD) at temperatures in the range of 80-300  ̊C using titanium tetrachloride (TiCl4) as Ti precursor and water as the oxidant. The influence of TiO2 thickness (5, 10, 20 nm), presence of additional tunneling interlayer (SiO2 or Al2O3...

  20. Modified Grid-Connected CSI for Hybrid PV/Wind Power Generation System

    Directory of Open Access Journals (Sweden)

    D. Amorndechaphon

    2012-01-01

    Full Text Available The principle of a power conditioning unit for hybrid PV/wind power generation system is proposed. The proposed power conditioner is based on the current source inverter (CSI topology. All energy sources are connected in parallel with a DC-bus through the modified wave-shaping circuits. To achieve the unity power factor at the utility grid, the DC-link current can be controlled via the wave-shaping circuits with the sinusoidal PWM scheme. In this work, the carrier-based PWM scheme is also proposed to minimize the utility current THD. The power rating of the proposed system can be increased by connecting more PV/wind modules through their wave-shaping circuits in parallel with the other modules. The details of the operating principles, the system configurations, and the design considerations are described. The effectiveness of the proposed CSI is demonstrated by simulation results.

  1. CsI as Multifunctional Redox Mediator for Enhanced Li-Air Batteries.

    Science.gov (United States)

    Lee, Chan Kyu; Park, Yong Joon

    2016-04-06

    We introduce CsI as a multifunctional redox mediator to enhance the performance of Li-air batteries. CsI dissolved in the electrolyte is ionized into Cs(+) and I(-), which perform their roles in the Li anode and air electrode, respectively. The I(-) ions in the electrolyte facilitate the dissolution of Li2O2 in the air electrode as a redox mediator, which reduces the overpotential of the cell. The low overpotential also leads to the suppression of parasitic reactions occurring in the high-voltage range, such as the decomposition of the electrolyte and the reaction between Li2O2 and carbon. At the same time, the Cs(+) ions act as an electrostatic shield at the sharp points of the Li anode, hindering the growth of Li dendrite. The combined effects of reduced parasitic reactions and hindered Li-dendrite growth successfully improve the cyclic performance of Li-air cells.

  2. Update of the Italian Seismic Catalog (2003-2007) Catalogo della Sismicità Italiana CSI v2.0

    OpenAIRE

    Castello, Barbara; Di Stefano, Raffaele; Chiarabba, Claudio

    2009-01-01

    Earthquake catalogues are the basic tools that furnish parametric data for seismic hazard evaluation, studies on evolution of seismic sequences and earthquake occurrence. The INGV seismic network covers a large part of the italian region and it is complemented by several regional permanent network handled by other institutions. CSI results from the combination of INGV seismic bulletin with bulletins produced by other institutions. To update CSI from previous release to version 2.0 we co...

  3. 49th Annual Convention of the Computer Society of India CSI

    CERN Document Server

    Govardhan, A; Raju, K; Mandal, J

    2015-01-01

    Volume 1 contains 73 papers presented at CSI 2014: Emerging ICT for Bridging the Future: Proceedings of the 49th Annual Convention of Computer Society of India. The convention was held during 12-14, December, 2014 at Hyderabad, Telangana, India. This volume contains papers mainly focused on Fuzzy Systems, Image Processing, Software Engineering, Cyber Security and Digital Forensic, E-Commerce, Big Data, Cloud Computing and ICT applications.

  4. Imphal-Kohima: Encirclement, 8 March-22 June 1944 (CSI Battlebook 10-C)

    Science.gov (United States)

    1984-05-01

    contents have not been edited or checked in detail for tactual veracity. The views expressed in CSI BATTLEBOOKS are those of the authors and not...is the true lesson learned from this campaign. The Allied forces did not rea- "l_ ze the true capability or abilities of the air forces, and yet a...campaigns, the Japanese ’. still had not learned how to do this. They did not trust units of the Indian Nationalist Army under their command and

  5. Light response of pure CsI calorimeter crystals painted with wavelength-shifting lacquer

    CERN Document Server

    Frlez, E; Krause, B; Pocanic, D; Renker, D; Ritt, S; Slocum, P L; Supek, I; Wirtz, H P; Broennimann, Ch.

    2001-01-01

    We have measured scintillation properties of pure CsI crystals used in the shower calorimeter built for a precise determination of the pi+ -> pi0 e+ nu decay rate at the Paul Scherrer Institute (PSI). All 240 individual crystals painted with a special wavelength-shifting solution were examined in a custom-build detection apparatus (RASTA=radioactive source tomography apparatus) that uses a 137Cs radioactive gamma source, cosmic muons and a light emitting diode as complementary probes of the scintillator light response. We have extracted the total light output, axial light collection nonuniformities and timing responses of the individual CsI crystals. These results predict improved performance of the 3 pi sr PIBETA calorimeter due to the painted lateral surfaces of 240 CsI crystals. The wavelength-shifting paint treatment did not affect appreciably the total light output and timing resolution of our crystal sample. The predicted energy resolution for positrons and photons in the energy range of 10-100 MeV was ...

  6. Enhanced field electron emission of graphene sheets by CsI coating after electrophoretic deposition.

    Science.gov (United States)

    Liu, Jianlong; Zeng, Baoqing; Wu, Zhe; Sun, Hao

    2012-03-01

    Because of the large quantities of edges, graphene can serve as an efficient edge emitter for field emission (FE). Cesium iodide (CsI) coating was promising to enhance the electron emission and utilized in FE applications. In this work, FE of graphene sheets after electrophoretic deposition (ED) was studied. Electron emission property of GS was obviously improved by coating with CsI. The turn-on field of GS decreased from 4.4 to 2.5 V/ μm; and threshold field decreased from 9 to 5.8 V/μm, respectively. This FE improvement must due to a higher effective density of emission site generated around the GS surface after coating. Scanning electron microscopy (SEM) and computation were taken to reveal the influence after coating. Investigations of CsI coated MWCNTs were also compared in order to better understand the origin of the low turn-on electric field obtained by GS. © 2012 American Chemical Society

  7. Integrated design of the CSI evolutionary structure: A verification of the design methodology

    Science.gov (United States)

    Maghami, Peiman G.; Joshi, S. M.; Elliott, Kenny B.; Walz, J. E.

    1993-01-01

    One of the main objectives of the Controls-Structures Interaction (CSI) program is to develop and evaluate integrated controls-structures design methodology for flexible space structures. Thus far, integrated design methodologies for a class of flexible spacecraft, which require fine attitude pointing and vibration suppression with no payload articulation, have been extensively investigated. Various integrated design optimization approaches, such as single-objective optimization, and multi-objective optimization, have been implemented with an array of different objectives and constraints involving performance and cost measures such as total mass, actuator mass, steady-state pointing performance, transient performance, control power, and many more. These studies have been performed using an integrated design software tool (CSI-DESIGN CODE) which is under development by the CSI-ADM team at the NASA Langley Research Center. To date, all of these studies, irrespective of the type of integrated optimization posed or objectives and constraints used, have indicated that integrated controls-structures design results in an overall spacecraft design which is considerably superior to designs obtained through a conventional sequential approach. Consequently, it is believed that validation of some of these results through fabrication and testing of a structure which is designed through an integrated design approach is warranted. The objective of this paper is to present and discuss the efforts that have been taken thus far for the validation of the integrated design methodology.

  8. Development of Large Area CsI Photocathodes for the ALICE/HMPID RICH Detector

    CERN Document Server

    Hoedlmoser, H; Schyns, E

    2005-01-01

    The work carried out within the framework of this PhD deals with the measurement of the photoelectric properties of large area thin film Cesium Iodide (CsI) photocathodes (PCs) which are to be used as a photon converter in a proximity focusing RICH detector for High Momentum Particle Identification (HMPID) in the ALICE experiment at the LHC. The objective was to commission a VUV-scanner setup for in-situ measurements of the photoelectric response of the CsI PCs immediately after the thin film coating process and the use of this system to investigate the properties of these photon detectors. Prior to this work and prior to the finalization of the ALICE/HMPID detector design, R&D work investigating the properties of CsI PCs had been performed at CERN and at other laboratories in order to determine possible substrates and optimized thin film coating procedures. These R&D studies were usually carried out with small samples on different substrates and with various procedures with sometimes ambiguous result...

  9. Minimax robust power split in AF relays based on uncertain long-term CSI

    KAUST Repository

    Nisar, Muhammad Danish

    2011-09-01

    An optimal power control among source and relay nodes in presence of channel state information (CSI) is vital for an efficient amplify and forward (AF) based cooperative communication system. In this work, we study the optimal power split (power control) between the source and relay node in presence of an uncertainty in the CSI. The prime contribution is to solve the problem based on an uncertain long-term knowledge of both the first and second hop CSI (requiring less frequent updates), and under an aggregate network-level power constraint. We employ the minimax optimization methodology to arrive at the minimax robust optimal power split, that offers the best possible guarantee on the end-to-end signal to noise ratio (SNR). The derived closed form analytical expressions admit simple intuitive interpretations and are easy to implement in real-world AF relaying systems. Numerical results confirm the advantages of incorporating the presence of uncertainty into the optimization problem, and demonstrate the usefulness of the proposed minimax robust optimal power split. © 2011 IEEE.

  10. A Scalable Framework for CSI Feedback in FDD Massive MIMO via DL Path Aligning

    Science.gov (United States)

    Luo, Xiliang; Cai, Penghao; Zhang, Xiaoyu; Hu, Die; Shen, Cong

    2017-09-01

    Unlike the time-division duplexing (TDD) systems, the downlink (DL) and uplink (UL) channels are not reciprocal anymore in the case of frequency-division duplexing (FDD). However, some long-term parameters, e.g. the time delays and angles of arrival (AoAs) of the channel paths, still enjoy reciprocity. In this paper, by efficiently exploiting the aforementioned limited reciprocity, we address the DL channel state information (CSI) feedback in a practical wideband massive multiple-input multiple-output (MIMO) system operating in the FDD mode. With orthogonal frequency-division multiplexing (OFDM) waveform and assuming frequency-selective fading channels, we propose a scalable framework for the DL pilots design, DL CSI acquisition, and the corresponding CSI feedback in the UL. In particular, the base station (BS) can transmit the FFT-based pilots with the carefully-selected phase shifts. Then the user can rely on the so-called time-domain aggregate channel (TAC) to derive the feedback of reduced imensionality according to either its own knowledge about the statistics of the DL channels or the instruction from the serving BS. We demonstrate that each user can just feed back one scalar number per DL channel path for the BS to recover the DL CSIs. Comprehensive numerical results further corroborate our designs.

  11. On the Secrecy Capacity Region of the Block-Fading BCC with Limited CSI Feedback

    KAUST Repository

    Hyadi, Amal

    2017-02-07

    In this work, we examine the secrecy capacity region of the block-fading broadcast channel with confidential messages (BCC) when the transmitter has limited knowledge of the channel. In particular, we consider a two-user communication system where the transmitter has one common message to be transmitted to both users and one confidential message intended to only one of them. The confidential message has to be kept secret from the other user to whom the information is not intended. The transmitter is not aware of the channel state information (CSI) of neither channel and is only provided by limited CSI feedback sent at the beginning of each fading block. Assuming an error-free feedback link, we characterize the secrecy capacity region of this channel and show that even with a 1-bit CSI feedback, a positive secrecy rate can still be achieved. Then, we look at the case where the feedback link is not error- free and is rather a binary erasure channel (BEC). In the latter case, we provide an achievable secrecy rate region and show that as long as the erasure event is not a probability 1 event, the transmitter can still transmit the confidential information with a positive secrecy rate.

  12. Secure Communication for Two-Way Relay Networks with Imperfect CSI

    Directory of Open Access Journals (Sweden)

    Cong Sun

    2017-09-01

    Full Text Available This paper considers a two-way relay network, where two legitimate users exchange messages through several cooperative relays in the presence of an eavesdropper, and the Channel State Information (CSI of the eavesdropper is imperfectly known. The Amplify-and-Forward (AF relay protocol is used. We design the relay beamforming weights to minimize the total relay transmit power, while requiring the Signal-to-Noise-Ratio (SNRs of the legitimate users to be higher than the given thresholds and the achievable rate of the eavesdropper to be upper-bounded. Due to the imperfect CSI, a robust optimization problem is summarized. A novel iterative algorithm is proposed, where the line search technique is applied, and the feasibility is preserved during iterations. In each iteration, two Quadratically-Constrained Quadratic Programming (QCQP subproblems and a one-dimensional subproblem are optimally solved. The optimality property of the robust optimization problem is analyzed. Simulation results show that the proposed algorithm performs very close to the non-robust model with perfect CSI, in terms of the obtained relay transmit power; it~achieves higher secrecy rate compared to the existing work. Numerically, the proposed algorithm converges very quickly, and more than 85% of the problems are solved optimally.

  13. B1-based SAR reconstruction using contrast source inversion-electric properties tomography (CSI-EPT).

    Science.gov (United States)

    Balidemaj, Edmond; van den Berg, Cornelis A T; van Lier, Astrid L H M W; Nederveen, Aart J; Stalpers, Lukas J A; Crezee, Hans; Remis, Rob F

    2017-02-01

    Specific absorption rate (SAR) assessment is essential for safety purposes during MR acquisition. Online SAR assessment is not trivial and requires, in addition, knowledge of the electric tissue properties and the electric fields in the human anatomy. In this study, the potential of the recently developed CSI-EPT method to reconstruct SAR distributions is investigated. This method is based on integral representations for the electromagnetic field and attempts to reconstruct the tissue parameters and the electric field strength based on [Formula: see text] field data only. Full three-dimensional FDTD simulations using a female pelvis model are used to validate two-dimensional CSI reconstruction results in the central transverse plane of a 3T body coil. Numerical experiments demonstrate that the reconstructed SAR distributions are in good agreement with the SAR distributions as determined via 3D FDTD simulations and show that these distributions can be computed very efficiently in the central transverse plane of a body coil with the two-dimensional approach of CSI-EPT.

  14. Caveats Concerning the Use of SRTM DEM Version 4.1 (CGIAR-CSI

    Directory of Open Access Journals (Sweden)

    John Peter Merryman Boncori

    2016-09-01

    Full Text Available This paper provides some recommendations concerning the use of version 4.1 of the near-global 3 arcsec Shuttle Radar Topography Mission (SRTM Digital Elevation Model (DEM distributed by the Consortium for Spatial Information (CGIAR-CSI. This product is considered by most users to be a void-filled version of the finished grade NASA SRTM DEM. However, in non-void areas, these DEMs can exhibit relative geolocation shifts and spatially correlated elevation differences up to tens of meters, the location and extent of which depends on the geographical location and on the download mirror of the version 4.1 product. Such differences are found to be partly due to changes introduced by NASA SRTM version 2.1, with respect to NASA SRTM version 2.0, on which CGIAR-CSI version 4.1 is based, and partly to processing and/or annotation errors affecting the CGIAR-CSI version 4.1 DEMs.

  15. Full-Duplex Bidirectional Secure Communications Under Perfect and Distributionally Ambiguous Eavesdropper's CSI

    Science.gov (United States)

    Li, Qiang; Zhang, Ying; Lin, Jingran; Wu, Sissi Xiaoxiao

    2017-09-01

    Consider a full-duplex (FD) bidirectional secure communication system, where two communication nodes, named Alice and Bob, simultaneously transmit and receive confidential information from each other, and an eavesdropper, named Eve, overhears the transmissions. Our goal is to maximize the sum secrecy rate (SSR) of the bidirectional transmissions by optimizing the transmit covariance matrices at Alice and Bob. To tackle this SSR maximization (SSRM) problem, we develop an alternating difference-of-concave (ADC) programming approach to alternately optimize the transmit covariance matrices at Alice and Bob. We show that the ADC iteration has a semi-closed-form beamforming solution, and is guaranteed to converge to a stationary solution of the SSRM problem. Besides the SSRM design, this paper also deals with a robust SSRM transmit design under a moment-based random channel state information (CSI) model, where only some roughly estimated first and second-order statistics of Eve's CSI are available, but the exact distribution or other high-order statistics is not known. This moment-based error model is new and different from the widely used bounded-sphere error model and the Gaussian random error model. Under the consider CSI error model, the robust SSRM is formulated as an outage probability-constrained SSRM problem. By leveraging the Lagrangian duality theory and DC programming, a tractable safe solution to the robust SSRM problem is derived. The effectiveness and the robustness of the proposed designs are demonstrated through simulations.

  16. Ki-67 immunoreactivity in meningiomas--determination of the proliferative potential of meningiomas using the monoclonal antibody Ki-67

    DEFF Research Database (Denmark)

    Madsen, C; Schrøder, H D

    1997-01-01

    The proliferative potential of 66 human intracranial meningiomas (15 benign, 15 atypical, 15 recurrent, 13 bone-invasive, and 8 brain-invasive) was investigated by means of immunohisto-chemistry using the monoclonal antibody Ki-67. This antibody recognizes a nuclear antigen present in human cells...... during all active phases of the cell cycle, but absent in the resting phase. The purpose of this retrospective study was to estimate the Ki-67-labelling index (L.I.) and see if this index could help discriminate between the different groups of meningiomas. Our results demonstrated that L.I. could...... discriminate between benign, bone-invasive/atypical, brain-invasive meningiomas. In the recurrent group of meningiomas the L.I. decreased from the first to the last operation. We conclude that estimation of L.I. at the time of the operation might help identify meningiomas with a high growth potential...

  17. Does evaporation paradox exist in China?

    Directory of Open Access Journals (Sweden)

    Z. T. Cong

    2009-03-01

    Full Text Available One expected consequence of global warming is the increase in evaporation. However, lots of observations show that the rate of evaporation from open pans of water has been steadily decreasing all over the world in the past 50 years. The contrast between expectation and observation is called "evaporation paradox". Based on data from 317 weather stations in China from 1956 to 2005, the trends of pan evaporation and air temperature were obtained and evaporation paradox was analyzed. The conclusions include: (1 From 1956 to 2005, pan evaporation paradox existed in China as a whole while pan evaporation kept decreasing and air temperature became warmer and warmer, but it does not apply to Northeast and Southeast China; (2 From 1956 to 1985, pan evaporation paradox existed narrowly as a whole with unobvious climate warming trend, but it does not apply to Northeast China; (3 From 1986 to 2005, in the past 20 years, pan evaporation paradox did not exist for the whole period while pan evaporation kept increasing, although it existed in South China. Furthermore, the trend of other weather factors including sunshine duration, windspeed, humidity and vapor pressure deficit, and their relations with pan evaporation are discussed. As a result, it can be concluded that pan evaporation decreasing is caused by the decreasing in radiation and wind speed before 1985 and pan evaporation increasing is caused by the decreasing in vapor pressure deficit due to strong warming after 1986. With the Budyko curve, it can be concluded that the actual evaporation decreased in the former 30 years and increased in the latter 20 year for the whole China.

  18. Evaporative oxidation treatability test report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-04-01

    In 1992, Congress passed the Federal Facilities Compliance Act that requires the U.S. Department of Energy (DOE) to treat and dispose of its mixed waste in accordance with the Resource Conservation and Recovery Act (RCRA) land disposal restrictions (LDRs). In response to the need for mixed-waste treatment capacity where available off-site commercial treatment facilities do not exist or cannot be used, the DOE Albuquerque Operations Office (DOE-AL) organized a Treatment Selection Team to match mixed wastes with treatment options and develop a strategy for treatment of its mixed wastes. DOE-AL manages operations at nine sites with mixed-waste inventories. The Treatment Selection Team determined a need to develop mobile treatment capacity to treat wastes at the sites where the wastes are generated. Treatment processes used for mixed waste not only must address the hazardous component (i.e., meet LDRs) but also must contain the radioactive component in a form that allows final disposal while protecting workers, the public, and the environment. On the basis of recommendations of the Treatment Selection Team, DOE-AL assigned projects to the sites to bring mixed-waste treatment capacity on-line. The three technologies assigned to the DOE Grand Junction Projects Office (GJPO) are evaporative oxidation, thermal desorption, and treated wastewater evaporation. Rust Geotech, the DOE-GJPO prime contractor, was assigned to design and fabricate mobile treatment units (MTUs) for these three technologies and to deliver the MTUs to selected DOE-AL sites. To conduct treatability tests at the GJPO, Rust leased a pilot-scale evaporative oxidation unit from the Clemson Technical Center (CTC), Anderson, South Carolina. The purpose of this report is to document the findings and results of tests performed using this equipment.

  19. Development of the Lesbian, Gay, and Bisexual Affirmative Counseling Self-Efficacy Inventory - Short Form (LGB-CSI-SF).

    Science.gov (United States)

    Dillon, Frank R; Alessi, Edward J; Craig, Shelley; Eber-Sole, Ryan C; Kumar, Snehal M; Spadola, Christine

    2015-03-01

    The Lesbian, Gay, and Bisexual Affirmative Counseling Self-Efficacy Inventory - Short Form (LGB-CSI-SF) was developed to facilitate LGB-affirmative counseling training, as well as process and outcome research, by offering a brief psychometrically supported version of the original LGB-CSI measure to researchers and clinicians. Five hundred seventy-five participants (435 licensed mental health professionals and 140 graduate students/trainees) constituted the sample. Confirmatory factor analyses of the 32 items from the original LGB-CSI yielded a new 15-item version of the measure composed of 5 factors (consisting of 3 items each) that assess counselor self-efficacy to perform lesbian, gay, and bisexual (LGB) affirmative counseling behaviors (Application of Knowledge, Advocacy Skills, Self-Awareness, Relationship, and Assessment). The LGB-CSI-SF evidenced high internal consistency and adequate test-retest stability. Convergent validity was supported by correlations between LGB-CSI-SF total scores and Application of Knowledge, Advocacy Skills, Relationship, and Assessment subscales and instruction in LGB issues, as well as personal/professional relations with LGB individuals. More affirmative attitudes toward LGB persons positively related with total scores and Advocacy Skills, Self-Awareness, and Relationship subscales. Discriminant validity was evidenced by an absence of relations between LGB-CSI-SF subscales and a measure of impression management. We found no associations between Advocacy Skills, Assessment, and Relationship subscales and a measure of Self-Deception. Recommendations for implementing the LGB-CSI-SF in future LGB-affirmative counseling self-efficacy based research and training interventions are discussed.

  20. Development of the Lesbian, Gay, and Bisexual Affirmative Counseling Self-Efficacy Inventory – Short Form (LGB-CSI-SF)

    Science.gov (United States)

    Dillon, Frank R.; Alessi, Edward J.; Craig, Shelley; Eber-sole, Ryan C.; Kumar, Snehal M.; Spadola, Christine

    2015-01-01

    The Lesbian, Gay, and Bisexual Affirmative Counseling Self-Efficacy Inventory – Short Form (LGB-CSI-SF) was developed to facilitate LGB-affirmative counseling training, as well as process and outcome research, by offering a brief psychometrically supported version of the original LGB-CSI measure to researchers and clinicians. Five hundred seventy-five participants (435 licensed mental health professionals and 140 graduate students/trainees) constituted the sample. Confirmatory factor analyses of the 32 items from the original LGB-CSI yielded a new 15-item version of the measure composed of 5 factors (consisting of 3 items each) that assess counselor self-efficacy to perform lesbian, gay, and bisexual (LGB) affirmative counseling behaviors (Application of Knowledge, Advocacy Skills, Self-Awareness, Relationship, and Assessment). The LGB-CSI-SF evidenced high internal consistency and adequate test–retest stability. Convergent validity was supported by correlations between LGB-CSI-SF total scores and Application of Knowledge, Advocacy Skills, Relationship, and Assessment subscales and instruction in LGB issues, as well as personal/professional relations with LGB individuals. More affirmative attitudes toward LGB persons positively related with total scores and Advocacy Skills, Self-Awareness, and Relationship subscales. Discriminant validity was evidenced by an absence of relations between LGB-CSI-SF subscales and a measure of impression management. We found no associations between Advocacy Skills, Assessment, and Relationship subscales and a measure of Self-Deception. Recommendations for implementing the LGB-CSI-SF in future LGB-affirmative counseling self-efficacy based research and training interventions are discussed. PMID:25992391

  1. Oralno kirurški zahvati kod djece

    OpenAIRE

    Gračan, Boris

    2015-01-01

    Oralno kirurški zahvati kod djece su jedinstveni, jer su vezani uz određen uzrast i po mnogo čemu se razlikuju od zahvata kod odraslih pacijenata. Dječji uzrast karakteriziraju mnoge anatomske, morfološke i histološke specifičnosti kao što je građa kosti, resorbirani korijenovi mliječnih zuba, pojava prekobrojnih zuba, te neke anomalije mekih tkiva. Od velike je važnosti suradnja djeteta, odnosno liječnikov pristup djetetu, gdje se od stomatologa očekuje poznavanje i primjenjivanje mnogih bih...

  2. Dentinogena cista upalnog podrijetla: dijagnostički izazov

    OpenAIRE

    BHARI SHARANESHA, Manjunatha; GOWDA SADASHIVAPPA, Deepak Pateel

    2010-01-01

    Odontogene ciste obično se otkrivaju tijekom rutinskoga pregleda u stomatološkoj ordinaciji, a prema podrijetlu mogu biti razvojne ili upalne. Obično su destruktivne za okolne strukture - kako za kost tako i za zube. Moramo istaknuti da različite vrste cista vrlo često radiografski i histopatološki daju sličnu kliničku sliku. U takvim slučajevima točna dijagnoza ovisi o korelaciji svih navedenih nalaza. Dentinogene ciste su one koje zatvara kruna neniklih zuba širenjem folikula i - kako je pr...

  3. Simbolisme Kompleks Bangunan Situs Ki Buyut Trusmi Cirebon

    Directory of Open Access Journals (Sweden)

    Muhammad Al Mujabuddawat

    2016-12-01

    Full Text Available Ki Buyut Trusmi Site is a burial site bounded by walls surrounding the complex site. In the complex area of the site, several buildings scattered in the barrier wall of the spatial division sites as many as 4 cemetery yard; West, East, Central, and North. The buildings are in the midst of hundreds of tombs in the complex area of the site. Based on the results of an overview of the physical form and position of the object of those buildings, it is understood that every buildings has its function and symbolic meaning. The position of the components of the building symbolically form a plan groove toward the main location of the most sanctified, the graves of Ki Gede Trusmi and Prince Trusmi in North yard site. Based on symbolic significance and hundred of tombs scattered in the area of the site, they are clearly show a blend of Islamic buildings affected by local culture which already existed, with the animism and Hindu-Buddhist. Those cultural blends form a pre-Islamic cultural treasures material which tangible on the architecture of the building full of symbolism outside the real Islamic law. Local culture become part of construction to the Islamization of local communities, Islam developed in the area Trusmi shows Islamic character integrative and accommodating to the local indigenous community.   Situs Ki Buyut Trusmi merupakan situs pemakaman yang dibatasi oleh tembok keliling yang mengelilingi kompleks situs. Dalam area kompleks situs, berdiri sejumlah bangunan yang tersebar dalam sekat-sekat tembok pembagian halaman situs sebanyak 4 halaman, yaitu Halaman barat, Halaman timur, Halaman tengah, dan Halaman utara. Bangunan-bangunan tersebut berdiri ditengah-tengah ratusan makam di dalam area kompleks situs. Berdasarkan hasil tinjauan terhadap bentuk fisik dan keletakan dari objek bangunan-bangunan tersebut, diketahui memiliki fungsi dan makna simbolik tersendiri. Keletakan komponen-komponen bangunannya secara simbolis membentuk denah alur

  4. KRIMINOLOŠKI POGLED NASILJA NA ŠPORTNIH PRIREDITVAH

    OpenAIRE

    Knez Grah, Elena

    2016-01-01

    V svoji diplomski nalogi sem iz kriminološkega vidika natančno obdelala vzroke in razloge zaradi katerih prihaja do nasilja na športnih prireditvah. Razumevanje vzrokov je namreč ključnega pomena za razumevanje same agresivnosti in nasilja. Poznamo več klasifikacij nasilja in prav tako več vrst. Najbolj poznana kategorizacija agresivnosti je delitev, po Frommu, in sicer, na benigno in maligno agresivnost. Benigna agresivnost je tista agresivnost, ki je lastna vsem živim bitjem in nam je ...

  5. EKOLOŠKI TURIZEM - PRIHODNOST JUTRIŠNJEGA DNE

    OpenAIRE

    Gorjanc, Martin

    2010-01-01

    V prvem poglavju diplomskega seminarja z naslovom »Ekoturizem, prihodnost jutrišnjega dne« smo opredelili področje oziroma problem, predstavili namen dokumenta, navedli tudi cilje in osnovne trditve ter predpostavke in omejitve. Tematika je aktualna, saj gre za analizo vidnih sprememb v vedenju potrošnikov glede načina prehranjevanja. Osnovna teza je bila, da je v Mariboru dovolj povpraševanja po ekološki gostinski ponudbi, da lahko restavracija, v kateri strežejo ekološko pridelano hrano, po...

  6. Kosa - biološki uzorak za analizu droga

    OpenAIRE

    Skender, Ljiljana

    2001-01-01

    Opisane su glavne značajke kose kao biološkog uzorka, mehanizmi ulaza droga u kosu, njihova zadržavanja i nestajanja. Budući da se većina metoda za određivanje droga u kosi koristi vezanim sustavom plinski kromatografspektrometar masa (GC/MS), samo su te metode i prikazane. U pravilu svaka se metoda sastoji od pranja kose, usitnjavanja, ekstrakcije, pročišćavanja i derivatizacije. Dok je analitički postupak obrade kose gotovo do potankosti razrađen, u interpretaciji rezultata droga u kosi još...

  7. Hydrodynamic Instabilities Produced by Evaporation

    Science.gov (United States)

    Romo-Cruz, Julio Cesar Ruben; Hernandez-Zapata, Sergio; Ruiz-Chavarria, Gerardo

    2012-11-01

    When a liquid layer (alcohol in the present work) is in an environment where its relative humidity is less than 100 percent evaporation appears. When RH is above a certain threshold the liquid is at rest. If RH decreases below this threshold the flow becomes unstable, and hydrodynamic cells develop. The aim of this work is to understand the formation of those cells and its main features. Firstly, we investigate how the cell size depends on the layer width. We also study how temperature depends on the vertical coordinate when the cells are present. An inverse temperature gradient is found, that is, the bottom of liquid layer is colder than the free surface. This shows that the intuitive idea that the cells are due to a direct temperature gradient, following a Marangoni-like process, does not work. We propose the hypothesis that the evaporation produce a pressure gradient that is responsible of the cell development. On the other hand, using a Schlieren technique we study the topography of the free surface when cells are present. Finally the alcohol vapor layer adjacent to the liquid surface is explored using scattering experiments, giving some insight on the plausibility of the hypothesis described previously. Authors acknowledge support by DGAPA-UNAM under project IN116312 ``Vorticidad y ondas no lineales en fluidos.''

  8. Can Ki-67 Play a Role in Prediction of Breast Cancer Patients' Response to Neoadjuvant Chemotherapy?

    Directory of Open Access Journals (Sweden)

    Juhasz-Böss Ingolf

    2014-01-01

    Full Text Available Background. Currently the choice of breast cancer therapy is based on prognostic factors. The proliferation marker Ki-67 is used increasingly to determine the method of therapy. The current study analyses the predictive value of Ki-67 in foreseeing breast cancer patients’ responses to neoadjuvant chemotherapy. Methods. This study includes patients with invasive breast cancer treated between 2008 and 2013. The clinical response was assessed by correlating Ki-67 to histological examination, mammography, and ultrasonography findings. Results. The average Ki-67 value in our patients collectively (n=77 is 34.9 ± 24.6%. The average Ki-67 value is the highest with 37.4 ± 24.0% in patients with a pCR. The Ki-67 values do not differ significantly among the 3 groups: pCR versus partial pathological response versus stable disease/progress (P=0.896. However, Ki-67 values of patients with luminal, Her2 enriched, and basal-like cancers differed significantly from each other. Furthermore, within the group of luminal tumors Ki-67 values of patients with versus without pCR also differed significantly. Conclusion. Our data shows that the Ki-67 value predicts the response to neoadjuvant chemotherapy as a function of the molecular subtype, reflecting the daily routine concerning Ki-67 and its impressing potential and limitation as a predictive marker for neoadjuvant chemotherapy response.

  9. New models for droplet heating and evaporation

    KAUST Repository

    Sazhin, Sergei S.

    2013-02-01

    A brief summary of new models for droplet heating and evaporation, developed mainly at the Sir Harry Ricardo Laboratory of the University of Brighton during 2011-2012, is presented. These are hydrodynamic models for mono-component droplet heating and evaporation, taking into account the effects of the moving boundary due to evaporation, hydrodynamic models of multi-component droplet heating and evaporation, taking and not taking into account the effects of the moving boundary, new kinetic models of mono-component droplet heating and evaporation, and a model for mono-component droplet evaporation, based on molecular dynamics simulation. The results, predicted by the new models are compared with experimental data and the prehctions of the previously developed models where possible. © 2013 Asian Network for Scientific Information.

  10. Molecular cloning and characterization of Siamese crocodile (Crocodylus siamensis) copper, zinc superoxide dismutase (CSI-Cu,Zn-SOD) gene.

    Science.gov (United States)

    Sujiwattanarat, Penporn; Pongsanarakul, Parinya; Temsiripong, Yosapong; Temsiripong, Theeranan; Thawornkuno, Charin; Uno, Yoshinobu; Unajak, Sasimanas; Matsuda, Yoichi; Choowongkomon, Kiattawee; Srikulnath, Kornsorn

    2016-01-01

    Superoxide dismutase (SOD, EC 1.15.1.1) is an antioxidant enzyme found in all living cells. It regulates oxidative stress by breaking down superoxide radicals to oxygen and hydrogen peroxide. A gene coding for Cu,Zn-SOD was cloned and characterized from Siamese crocodile (Crocodylus siamensis; CSI). The full-length expressed sequence tag (EST) of this Cu,Zn-SOD gene (designated as CSI-Cu,Zn-SOD) contained 462bp encoding a protein of 154 amino acids without signal peptides, indicated as intracellular CSI-Cu,Zn-SOD. This agreed with the results from the phylogenetic tree, which indicated that CSI-Cu,Zn-SOD belonged to the intracellular Cu,Zn-SOD. Chromosomal location determined that the CSI-Cu,Zn-SOD was localized to the proximal region of the Siamese crocodile chromosome 1p. Several highly conserved motifs, two conserved signature sequences (GFHVHEFGDNT and GNAGGRLACGVI), and conserved amino acid residues for binding copper and zinc (His(47), His(49), His(64), His(72), His(81), Asp(84), and His(120)) were also identified in CSI-Cu,Zn-SOD. Real-time PCR analysis showed that CSI-Cu,Zn-SOD mRNA was expressed in all the tissues examined (liver, pancreas, lung, kidney, heart, and whole blood), which suggests a constitutively expressed gene in these tissues. Expression of the gene in Escherichia coli cells followed by purification yielded a recombinant CSI-Cu,Zn-SOD, with Km and Vmax values of 6.075mM xanthine and 1.4×10(-3)mmolmin(-1)mg(-1), respectively. This Vmax value was 40 times lower than native Cu,Zn-SOD (56×10(-3)mmolmin(-1)mg(-1)), extracted from crocodile erythrocytes. This suggests that cofactors, protein folding properties, or post-translational modifications were lost during the protein purification process, leading to a reduction in the rate of enzyme activity in bacterial expression of CSI-Cu,Zn-SOD. Copyright © 2015 Elsevier Inc. All rights reserved.

  11. The deformation stimulated luminescence in KCl, KBr and KI crystals

    Science.gov (United States)

    Shunkeyev, K.; Sergeyev, D.; Drozdowski, W.; Brylev, K.; Myasnikova, L.; Barmina, A.; Zhanturina, N.; Sagimbaeva, Sh; Aimaganbetova, Z.

    2017-05-01

    Currently, strengthening of the intensity of luminescence in alkali halide crystals (AHC) at lattice symmetry lowering is discussed as a promising direction for the development of scintillation detectors [1-3]. In this regard, for the study of anion excitons and radiation defects in the AHC anion sublattice at deformation, the crystals with the same sizes of cations and different sizes of anions were chosen. In the X-ray spectra of KCl at 10 K, the luminescence at 3.88 eV; 3.05 eV and 2.3 eV is clearly visible. The luminescence at 3.05 eV corresponds to the tunneling recharge [F*, H]. Luminescence at 3.88 eV is quenched in the region of thermal destruction of F‧-centers and characterizes tunneling recharge of F‧, VK-centers. In KCl at 90 K, the luminescence of self-trapped excitons (STE) is completely absent. In KBr at deformation not only STE luminescence, but also deformation stimulated luminescence at 3.58 eV were recorded, the last one corresponds to tunneling recharge of F‧, VK-centers. In KI crystal at 10 K and 90 K at deformation, only STE luminescence is enhanced. There are no deformation luminescence bands in KI compares with KBr and KCl crystals.

  12. Examination of the "CSI Effect" on Perceptions of Scientific and Testimonial Evidence in a Hong Kong Chinese Sample.

    Science.gov (United States)

    Hui, Cora Y T; Lo, T Wing

    2017-05-01

    Television is a powerful medium through which to convey information and messages to the public. The recent proliferation of forensic science and criminal justice information throughout all forms of media, coupled with raised expectations toward forensic evidence, has led some to suspect that a "CSI effect" ( Crime Scene Investigation effect) is taking place. The present study contributes to the literature addressing the CSI effect in two ways. First, it examines whether the CSI effect exists in the Chinese population of Hong Kong. Second, using a mock-jury paradigm, it empirically examines a more integrative perspective of the CSI effect. It was found that, although the amount of media coverage involving forensic evidence does influence participants' perception of legal evidence to some degree, such a perception does not affect participants' legal decision making. Viewers of forensic dramas were not more likely to convict the defendant when forensic evidence was presented and not less likely to convict when only testimonial evidence was presented. The only significant predictor of the defendant's culpability when scientific evidence was presented was participants' ratings of the reliability of scientific evidence. Results from the present study lend no support to the existence of the CSI effect in Hong Kong.

  13. The clinical performance of the Surevue, Focus, and CSI daily wear lenses in allergic and normal contact lens patients.

    Science.gov (United States)

    Bucci, F A; Tanner, J B; Moody, K J

    1994-07-01

    Sixty-three daily wear contact lens patients (42 non-allergic [66.7%] and 21 allergic [33.3%]) were randomized into three groups (CSI vs. Surevue; Focus vs. CSI; Focus vs. Surevue) and evaluated every two weeks for six months with regard to patient preferences and ranked symptom responses for 14 variables, including overall contact lens preference. Allergic patients (43.9 +/- 94.3 ng/mL) revealed significantly higher (P = .011) tear IgE levels versus non-allergic patients (15.6 +/- 25.8 ng/mL). Non-allergic patients preferred CSI over Surevue for 12 of 14 variables including overall lens preference (P lens preference (P lens preference (P preferred Focus over CSI for 8 of 14 variables; CSI over Surevue for 4 of 14 variables, including overall lens preference (P lens preference (P lens revealed decreasing symptoms over time, while the allergic patients showed no significant difference.(ABSTRACT TRUNCATED AT 250 WORDS)

  14. Role of evaporation in gravitational collapse

    CERN Document Server

    Baccetti, Valentina; Terno, Daniel R

    2016-01-01

    We study collapse of evaporating thin dust shells using two families of metrics to describe the {exterior geometry: the outgoing Vaidya metric and the retarded Schwarzschild metric. Both allow incorporation of Page's evaporation law (the latter in terms of the time at infinity), resulting in a modified equation} of motion for the shell. In these scenarios we find in each case that the collapse is accelerated due to evaporation, but the Schwarzschild radius is not crossed. Instead the shell is always at a certain sub-Planckian distance from this would-be horizon that depends only on the mass and evaporation rate.

  15. Physical Properties of C-Si Alloys in C2/m Structure

    Science.gov (United States)

    Wang, Qian-Kun; Chai, Chang-Chun; Fan, Qing-Yang; Yang, Yin-Tang

    2017-08-01

    Using the first principles calculations based on density functional theory, the crystal structure, elastic anisotropy, and electronic properties of carbon, silicon and their alloys (C 12 Si 4, C 8 Si 8, and C 4 Si 12 ) in a monoclinic structure (C2/m) are investigated. The calculated results such as lattice parameters, elastic constants, bulk modulus, and shear modulus of C 16 and Si 16 in C2/m structure are in good accord with previous work. The elastic constants show that C 16, Si 16, and their alloys in C2/m structure are mechanically stable. The calculated results of universal anisotropy index, compression and shear anisotropy percent factors indicate that C-Si alloys present elastic anisotropy, and C 8 Si 8 shows a greater anisotropy. The Poisson’s ratio and the B/G value show that C 8 Si 8 is ductile material and other four C-Si alloys are brittle materials. In addition, Debye temperature and average sound velocity are predicted utilizing elastic modulus and density of C-Si alloys. The band structure and the partial density of states imply that C 16 and Si 16 are indirect band gap semiconductors, while C 12 Si 4, C 8 Si 8, and C 4 Si 12 are semi-metallic alloys. Supported by the Natural Science Foundation of China under Grant No. 61474089, Open Fund of Key Laboratory of Complex Electromagnetic Environment Science and Technology, China Academy of Engineering Physics under Grant No. 2015-0214. YY.K

  16. Energy-Efficient Power Allocation of Cognitive Radio Systems without CSI at the Transmitter

    KAUST Repository

    Sboui, Lokman

    2015-01-07

    Two major issues are facing today’s wireless communications evolution: -Spectrum scarcity: Need for more bandwidth. As a solution, the Cognitive Radio (CR) paradigm, where secondary users (unlicensed) share the spectrum with licensed users, was introduced. -Energy consumption and CO2 emission: The ICT produce 2% of global CO2 emission (equivalent to the aviation industry emission). The cellular networks produces 0.2%. As solution energy efficient systems should be designed rather than traditional spectral efficient systems. In this work, we aim to determine the optimal energy efficient power allocation of CR when the channel state information at the transmitter CSI-T is not available.

  17. Experimental demonstration of a classical approach for flexible space structure control: NASA CSI testbeds

    Science.gov (United States)

    Bond, Wie

    1991-01-01

    The results of active control experiments performed for the Mini-Mast truss structure are presented. The primary research objectives were: (1) to develop active structural control concepts and/or techniques; (2) to verify the concept of robust non-minimum-phase compensation for a certain class of non-colocated structural control problems through ground experiments; (3) to verify a 'dipole' concept for persistent disturbance rejection control of flexible structures; and (4) to identify CSI (Control Structure Interaction) issues and areas of emphasis for the next generation of large flexible spacecraft. The classical SISO (Single Input and Single Output) control design approach was employed.

  18. On the low SNR capacity of log-normal turbulence channels with full CSI

    KAUST Repository

    Benkhelifa, Fatma

    2014-09-01

    In this paper, we characterize the low signal-To-noise ratio (SNR) capacity of wireless links undergoing the log-normal turbulence when the channel state information (CSI) is perfectly known at both the transmitter and the receiver. We derive a closed form asymptotic expression of the capacity and we show that it scales essentially as λ SNR where λ is the water-filling level satisfying the power constraint. An asymptotically closed-form expression of λ is also provided. Using this framework, we also propose an on-off power control scheme which is capacity-achieving in the low SNR regime.

  19. Clinical impact of ki-67 labeling index in non-small cell lung cancer

    DEFF Research Database (Denmark)

    Jakobsen, Jan Nyrop; Sørensen, Jens Benn

    2013-01-01

    The ki-67 index is a marker of proliferation in malignant tumors. Studies from the period 2000 to 2012 on the prognostic and predictive value of ki-67 labeling index (LI) in non-small cell cancer (NSCLC) are reviewed. Twenty-eight studies reported on the prognostic value of ki-67 index with various...... of ki-67 to chemotherapy and none revealed significant influence. Ki-67 index seems to be of prognostic influence in NSCLC although largely variable cut-off levels have been used in the various studies and standardization of methodology is required. The relative importance of ki-67 compared to newer...... biomarkers has not been explored. It is likely that a signature of several biomarkers in combination may be necessary to more sufficiently stratify patients to various treatment options than is currently possible, especially when it comes to the question of the optimal use of classical chemotherapy...

  20. Entropy Budget for Hawking Evaporation

    Directory of Open Access Journals (Sweden)

    Ana Alonso-Serrano

    2017-07-01

    Full Text Available Blackbody radiation, emitted from a furnace and described by a Planck spectrum, contains (on average an entropy of 3 . 9 ± 2 . 5 bits per photon. Since normal physical burning is a unitary process, this amount of entropy is compensated by the same amount of “hidden information” in correlations between the photons. The importance of this result lies in the posterior extension of this argument to the Hawking radiation from black holes, demonstrating that the assumption of unitarity leads to a perfectly reasonable entropy/information budget for the evaporation process. In order to carry out this calculation, we adopt a variant of the “average subsystem” approach, but consider a tripartite pure system that includes the influence of the rest of the universe, and which allows “young” black holes to still have a non-zero entropy; which we identify with the standard Bekenstein entropy.

  1. Growth Inhibition of Cultured Human Liver Carcinoma Cells by Ki-energy (Life-energy: Scientific Evidence for Ki-effects on Cancer Cells

    Directory of Open Access Journals (Sweden)

    Tsuyoshi Ohnishi

    2005-01-01

    Full Text Available ‘Ki-energy’ (life-energy is believed to increase the immune activity of its practitioners. It has also been shown to cause neuropsychological effects. We undertook this study to obtain objective and scientific evidence as to whether or not a ‘Ki-effect’ could inhibit the growth of cultured cancer cells. Cultured human liver carcinoma cells, HepG2, were used. A Japanese Ki-expert held his fingers toward the cells in culture dishes for 5 or 10 min. After culturing for 24 h, we measured cell numbers, protein concentration per cell, certain mRNA expressions and the synthesis of regucalcin. The results were compared with those for control cells (non-treated cells. We found that the number of cells in the Ki-exposed groups were less than those in the controls by 30.3 and 40.6% with 5 and 10 min Ki-exposure, respectively. The protein content per cell in the Ki-exposed groups (5 and 10 min was higher than that in the control groups by 38.8 and 62.9%, respectively. These results were statistically significant. Using RT–PCR, we found that the mRNA expression for c-myc, a tumor stimulator gene, was decreased, while that for regucalcin, which suppresses DNA synthesis, was increased. Our molecular biological studies and mathematical model analysis demonstrated that Ki-energy inhibited cancer cell division. The data also indicate that the Ki-effects involve some form of infrared radiation from the human body. This study suggests the possibility that Ki-energy may be beneficial for cancer patients because it suppresses cancer cell growth, and at the same time, it stimulates immune functions of the patients.

  2. Immunohistochemical study of KiSS1 and KiSS1R expression in human primary breast cancer: Association with breast cancer receptor status, proliferation markers and clinicopathological features.

    Science.gov (United States)

    Jarzabek, Katarzyna; Koda, Mariusz; Kozlowski, Leszek; Milewski, Robert; Wolczynski, Slawomir

    2015-06-01

    Recent studies have raised doubts about the protective role of KiSS1/KiSS1R in breast malignancy progression. However, the role of the KiSS1/KiSS1R system in primary breast cancer remains largely unknown. The aim of the present study was to characterize the biology and invasiveness potential of primary breast cancer through evaluation of KiSS1/KiSS1R protein expression and cellular localization with regard to lymph node metastasis status, receptor status (ERs, PR and HER-2/neu), and expression of aromatase, MMP-9, Ki-67 and Cyclin D1 in primary invasive breast cancer tissues. We showed increased protein expression of both KiSS1/KiSS1R and MMP-9 in the cancerous tissues compared with noncancerous tissue adjacent to the breast tumour. In the studied group of breast cancer samples, we observed a positive correlation between KiSS1 and MMP-9. We also showed a positive correlation between KiSS1R and aromatase expression in all studied breast cancers. We did not notice any associations between system and cell cycle regulators. KiSS1/KiSS1R did not correlate either with Cyclin D1 and Ki-67 or with receptor status. However, we showed higher levels of KiSS1R expression in ERα-negative cases than in ERα-positive cases in patients with lymph node metastasis. Present data do not confirm the protective role of KiSS1/KiSS1R in breast cancer progression, but our results do support the hypothesis that the KiSS1/KiSS1R system is activated even in primary breast cancer and sustained during invasion to local lymph nodes.

  3. Intrinsic Evaporative Cooling by Hygroscopic Earth Materials

    Directory of Open Access Journals (Sweden)

    Alexandra R. Rempel

    2016-08-01

    Full Text Available The phase change of water from liquid to vapor is one of the most energy-intensive physical processes in nature, giving it immense potential for cooling. Diverse evaporative cooling strategies have resulted worldwide, including roof ponds and sprinklers, courtyard fountains, wind catchers with qanats, irrigated green roofs, and fan-assisted evaporative coolers. These methods all require water in bulk liquid form. The evaporation of moisture that has been sorbed from the atmosphere by hygroscopic materials is equally energy-intensive, however, yet has not been examined for its cooling potential. In arid and semi-arid climates, hygroscopic earth buildings occur widely and are known to maintain comfortable indoor temperatures, but evaporation of moisture from their walls and roofs has been regarded as unimportant since water scarcity limits irrigation and rainfall; instead, their cool interiors are attributed to well-established mass effects in delaying the transmission of sensible gains. Here, we investigate the cooling accomplished by daily cycles of moisture sorption and evaporation which, requiring only ambient humidity, we designate as “intrinsic” evaporative cooling. Connecting recent soil science to heat and moisture transport studies in building materials, we use soils, adobe, cob, unfired earth bricks, rammed earth, and limestone to reveal the effects of numerous parameters (temperature and relative humidity, material orientation, thickness, moisture retention properties, vapor diffusion resistance, and liquid transport properties on the magnitude of intrinsic evaporative cooling and the stabilization of indoor relative humidity. We further synthesize these effects into concrete design guidance. Together, these results show that earth buildings in diverse climates have significant potential to cool themselves evaporatively through sorption of moisture from humid night air and evaporation during the following day’s heat. This finding

  4. Evaluation of Ki-67 Index in Core Needle Biopsies and Matched Breast Cancer Surgical Specimens.

    Science.gov (United States)

    Ahn, Soomin; Lee, Junghye; Cho, Min-Sun; Park, Sanghui; Sung, Sun Hee

    2017-11-16

    - The Ki-67 index is strongly prognostic and is used as a surrogate marker to distinguish luminal A from luminal B breast cancer types. - To investigate differences in Ki-67 index between core needle biopsy samples and matched surgical samples in breast cancer. - We included patients with invasive breast cancer who did not receive neoadjuvant therapy. A total of 89 pairs of core needle biopsies and surgical specimens were collected, and the Ki-67 index was assessed in hot spot areas using an image analyzer. We applied a 14% Ki-67 index to define low versus high groups. - The Ki-67 index was significantly higher in core needle biopsies than in surgical specimens (P biopsies but a low Ki-67 index in surgical samples. There were 10 cases (11.2%) that showed discordant luminal A/B types between core needle biopsy and the matched surgical specimen. The reasons for the discordance were poor staining of MIB1 accompanied by fixation issues and intratumoral heterogeneity of the Ki-67 index. - A significant difference in the Ki-67 index between core biopsy and surgical specimens was observed. Our findings indicate that it may be better to perform the Ki-67 assay on the core needle biopsy and the surgical specimen than on only one sample.

  5. Prognostic value of Ki-67 expression in conversion therapy for colorectal liver-limited metastases.

    Science.gov (United States)

    Hayashi, Hiromitsu; Beppu, Toru; Sakamoto, Yasuo; Miyamoto, Yuji; Yokoyama, Naomi; Higashi, Takaaki; Nitta, Hidetoshi; Hashimoto, Daisuke; Chikamoto, Akira; Baba, Hideo

    2015-01-01

    The objective of this study was to examine the prognostic value of Ki-67 expression in conversion therapy for colorectal liver-confined metastases. We enrolled a total of 96 patients including 54 patients who received oxaliplatin- or irinotecan-based chemotherapy and curative hepatectomy for initially unresectable metastases (conversion group) and 42 patients with initially resectable liver metastases (straight hepatectomy group). Ki-67 expression was examined in 96 resected specimens but excluded the 2 specimens that revealed no residual cancer cells in conversion group. Conversion therapy leads to greater survival that is equivalent to that straight hepatectomy group. In conversion group, high Ki-67 expression (> 30%) levels were detectable in 33 patients (64%) after chemotherapy prior to conversion therapy. High Ki-67 expression was significantly associated with shorter disease-free survival and worse overall survival (P conversion therapy. Interestingly, even in the patients with RECIST PR (n = 32), high Ki-67 expression was significantly shorter disease-free survival compared to low Ki-67 expression (P conversion group, there was no significant difference in disease free survival and overall survival between low (n = 14, 33%) and high (n = 28, 67%) Ki-67 expressions in patients with straight hepatectomy (P = 0.14 and 0.74, respectively). Residual Ki-67 expression is a useful biomarker for worse prognostic outcomes after conversion therapy. High Ki-67 expression may be a biomarker of micrometastases containing aggressive cancer cells.

  6. Suppression of cell division by pKi-67 antisense-RNA and recombinant protein.

    Science.gov (United States)

    Duchrow, M; Schmidt, M H; Zingler, M; Anemüller, S; Bruch, H P; Broll, R

    2001-01-01

    The human antigen defined by the monoclonal antibody Ki-67 (pKi-67) is a human nuclear protein strongly associated with cell proliferation and found in all tissues studied. It is widely used as a marker of proliferating cells, yet its function is unknown. To investigate its function we suppressed pKi-67 expression by antisense RNA and overexpressed a partial structure of pKi-67 in HeLa cells. A BrdU-incorporation assay showed a significant decrease in DNA synthesis after antisense inhibition. Cell cycle analysis indicated a higher proportion of cells in G1 phase and a lower proportion of cells in S phase while the number of G(2)/M phase cells remained constant. Overexpression of a recombinant protein encoding three of the repetitive elements from exon 13 of pKi-67 had a similar effect to that obtained by antisense inhibition. The similarity of the effect of expressing 'Ki-67 repeats' and pKi-67 antisense RNA could be explained by a negative effect on the folding of the endogenous protein in the endoplasmatic reticulum. Furthermore excessive self-association of pKi-67 via the repeat structure could inhibit its nuclear transport, preventing it from getting to its presumptive site of action. We conclude that the Ki-67 protein has an important role in the regulation of the cell cycle, which is mediated in part by its repetitive elements. Copyright 2001 S. Karger AG, Basel

  7. Generation of CsI cluster ions for mass calibration in matrix-assisted laser desorption/ionization mass spectrometry.

    Science.gov (United States)

    Lou, Xianwen; van Dongen, Joost L J; Meijer, E W

    2010-07-01

    A simple method was developed for the generation of cesium iodide (CsI) cluster ions up to m/z over 20,000 in matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS). Calibration ions in both positive and negative ion modes can readily be generated from a single MALDI spot of CsI(3) with 2-[(2E)-3-(4-tert-butylphenyl)-2-methylprop-2-enylidene] malononitrile (DCTB) matrix. The major cluster ion series observed in the positive ion mode is [(CsI)(n)Cs](+), and in the negative ion mode is [(CsI)(n)I](-). In both cluster series, ions spread evenly every 259.81 units. The easy method described here for the production of CsI cluster ions should be useful for MALDI MS calibrations. Copyright 2010 American Society for Mass Spectrometry. Published by Elsevier Inc. All rights reserved.

  8. Mass transfer relations for transpiration evaporation experiments

    NARCIS (Netherlands)

    Limpt, J.A.C. van; Beerkens, R.G.C.; Lankhorst, A.M.; Habraken, A.

    2005-01-01

    Transpiration evaporation experiments are often used to study evaporation kinetics from liquids or melts. The mass transport of volatile species in a transpiration experiment depends among others on the flow conditions of the carrier gas in the tube and on the geometrical configuration. For a

  9. Odors from evaporation of acidified pig urine

    NARCIS (Netherlands)

    Willers, H.C.; Hobbs, P.J.; Ogink, N.W.M.

    2004-01-01

    In the Dutch Hercules project feces and urine from pigs are collected separately underneath the slatted floor in a pig house and treated in two processes. Feces are composted and urine is concentrated by water evaporation in a packed bed. Exhaust air from the pig house is used for the evaporation in

  10. Spheroid droplets evaporation of water solutions

    OpenAIRE

    Misyura S. Y.; Morozov V.S.

    2017-01-01

    Droplet film boiling on a horizontal heating surface was studied experimentally. The heat transfer coefficient of droplet water solution in the spheroidal state decreases with a rise of wall overheating and spheroid diameter. Evaporation of small spheroid (diameter d 20 mm). At the evaporation of large spheroids a spheroid shape changes in time that significantly affect coefficients of generalizing curves that use dimensionless numbers.

  11. Evaporation experiments and modelling for glass melts

    NARCIS (Netherlands)

    Limpt, J.A.C. van; Beerkens, R.G.C.

    2007-01-01

    A laboratory test facility has been developed to measure evaporation rates of different volatile components from commercial and model glass compositions. In the set-up the furnace atmosphere, temperature level, gas velocity and batch composition are controlled. Evaporation rates have been measured

  12. Evaporation from partially covered water surfaces

    Science.gov (United States)

    Assouline, S.; Narkis, K.; Or, D.

    2010-10-01

    Evaporative losses from large water bodies may exceed 20% of water used in irrigated agriculture, with losses from reservoirs estimated at 50% of storage capacity. Prominent among proposed methods to curtail these evaporative losses are various forms of partial covers placed over water surfaces. Studies show that evaporation through perforated covers and from partially covered water surfaces exhibit nonlinear behavior, where rates of water loss are not proportional to uncovered surface fraction and are significantly affected by opening size and relative spacing. We studied evaporation from small water bodies under various perforated covers, extending the so-called diameter law to opening sizes in the range of 10-5 to 10-1 m. Contradicting claims concerning effects of openings and their arrangement on performance of evaporation barriers are analyzed on per opening and on per area mass losses. Our results help reconcile some classical findings invoking detailed pore-scale diffusion and simple temperature-based energetic behaviors. For fixed relative spacing, area-averaged evaporative flux density remains nearly constant across several orders of magnitude variations in opening size. For the scale of the experimental setup, we predict relative evaporation reduction efficiency for various configurations of perforated evaporation barriers.

  13. An evaporation based digital microflow meter

    NARCIS (Netherlands)

    Nie, C; Frijns, A J H; Mandamparambil, R; Zevenbergen, M A G; den Toonder, J M J

    2015-01-01

    In this work, we present a digital microflow meter operating in the range 30-250 nl min-1 for water. The principle is based on determining the evaporation rate of the liquid via reading the number of wetted pore array structures in a microfluidic system, through which continuous evaporation takes

  14. Advanced evaporator technology progress report FY 1992

    Energy Technology Data Exchange (ETDEWEB)

    Chamberlain, D.; Hutter, J.C.; Leonard, R.A. [and others

    1995-01-01

    This report summarizes the work that was completed in FY 1992 on the program {open_quotes}Technology Development for Concentrating Process Streams.{close_quotes} The purpose of this program is to evaluate and develop evaporator technology for concentrating radioactive waste and product streams such as those generated by the TRUEX process. Concentrating these streams and minimizing the volume of waste generated can significantly reduce disposal costs; however, equipment to concentrate the streams and recycle the decontaminated condensates must be installed. LICON, Inc., is developing an evaporator that shows a great deal of potential for this application. In this report, concepts that need to be incorporated into the design of an evaporator operated in a radioactive environment are discussed. These concepts include criticality safety, remote operation and maintenance, and materials of construction. Both solubility and vapor-liquid equilibrium data are needed to design an effective process for concentrating process streams. Therefore, literature surveys were completed and are summarized in this report. A model that is being developed to predict vapor phase compositions is described. A laboratory-scale evaporator was purchased and installed to study the evaporation process and to collect additional data. This unit is described in detail. Two new LICON evaporators are being designed for installation at Argonne-East in FY 1993 to process low-level radioactive waste generated throughout the laboratory. They will also provide operating data from a full-sized evaporator processing radioactive solutions. Details on these evaporators are included in this report.

  15. Optical properties of CsI single crystals irradiated with neutrons at low temperature

    Energy Technology Data Exchange (ETDEWEB)

    Okada, M. [Kyoto Univ., Kumatori, Osaka (Japan). Research Reactor Inst.; Nakagawa, M. [Faculty of Education, Kagawa Univ., Takamatsu, Kagawa (Japan); Atobe, K. [Faculty of Science, Naruto Univ. of Education, Naruto, Tokushima (Japan); Itatani, N.; Ozawa, K. [Horiba Ltd., Minamiku, Kyoto (Japan)

    1998-05-01

    Optical properties of the irradiation-induced-defects in neutron-irradiated CsI single crystals have been investigated. The nominally pure CsI crystals are irradiated by reactor fast neutrons (E>0.1 MeV) with a fluence of 1.4 x 10{sup 15} n/cm{sup 2} at 20 K and by {gamma}-rays from {sup 60}Co source to a dose of 1.5 x 10{sup 4} Gy at liquid nitrogen temperature (LNT). After the irradiations, isochronal annealings are performed to investigate the thermal behavior of the defects. The glow peaks of the thermoluminescence (TL) in each sample irradiated with neutrons at 20 K and with {gamma}-rays at LNT are observed at about 100, 160 and 220 K. In the neutron-irradiated samples at 20 K, the emission band at 338 nm is observed at LNT. It is supposed that this emission band occurs by an excitation of {gamma}-rays from {sup 134}Cs, which is radioactivated by thermal neutrons among the reactor radiations. It is confirmed that the temperature dependence of the 338 nm band is similar with that of the emission band due to the self-trapped exciton which is introduced into the non-irradiated samples illuminated by higher energy photons. (orig.) 13 refs.

  16. Downlink Linear Precoders Based on Statistical CSI for Multicell MIMO-OFDM

    Directory of Open Access Journals (Sweden)

    Ebrahim Baktash

    2017-01-01

    Full Text Available With 5G communication systems on the horizon, efficient interference management in heterogeneous multicell networks is more vital than ever. This paper investigates the linear precoder design for downlink multicell multiple-input multiple-output orthogonal frequency-division multiplexing (MIMO-OFDM systems, where base stations (BSs coordinate to reduce the interference across space and frequency. In order to minimize the overall feedback overhead in next-generation systems, we consider precoding schemes that require statistical channel state information (CSI only. We apply the random matrix theory to approximate the ergodic weighted sum rate of the system with a closed form expression. After formulating the approximation for general channels, we reduce the results to a more compact form using the Kronecker channel model for which several multicarrier concepts such as frequency selectivity, channel tap correlations, and intercarrier interference (ICI are rigorously represented. We find the local optimal solution for the maximization of the approximate rate using a gradient method that requires only the covariance structure of the MIMO-OFDM channels. Within this covariance structure are the channel tap correlations and ICI information, both of which are taken into consideration in the precoder design. Simulation results show that the rate approximation is very accurate even for very small MIMO-OFDM systems and the proposed method converges rapidly to a near-optimal solution that competes with networked MIMO and precoders based on instantaneous full CSI.

  17. Ultrafast laser direct hard-mask writing for high efficiency c-Si texture designs

    Directory of Open Access Journals (Sweden)

    Nogami Jun

    2013-03-01

    Full Text Available This study reports a high-resolution hard-mask laser writing technique to facilitate the selective etching of crystalline silicon (c-Si into an inverted-pyramidal texture with feature size and periodicity on the order of the wavelength which, thus, provides for both anti-reflection and effective light-trapping of infrared and visible light. The process also enables engineered positional placement of the inverted-pyramid thereby providing another parameter for optimal design of an optically efficient pattern. The proposed technique, a non-cleanroom process, is scalable for large area micro-fabrication of high-efficiency thin c-Si photovoltaics. Optical wave simulations suggest the fabricated textured surface with 1.3 μm inverted-pyramids and a single anti-reflective coating increases the relative energy conversion efficiency by 11% compared to the PERL-cell texture with 9 μm inverted pyramids on a 400 μm thick wafer. This efficiency gain is anticipated to improve further for thinner wafers due to enhanced diffractive light trapping effects.

  18. Opportunistic Energy-Aware Amplify-and-Forward Cooperative Systems with Imperfect CSI

    KAUST Repository

    Amin, Osama

    2015-07-29

    Recently, much attention has been paid to the green design of wireless communication systems using energy efficiency (EE) metrics that should capture all energy consumption sources to deliver the required data. In this paper, we design an energyefficient relay assisted communication system based on estimated channel state information (CSI). It employs amplify-andforward relaying and switches between different communication schemes, which are known as direct-transmission, two-hop and cooperative-transmission schemes, using the estimated CSI in order to maximize the EE. Two estimation strategies are assumed, namely disintegrated channel estimation and cascaded channel estimation. To formulate an accurate EE metric for the proposed opportunistic amplify-and-forward system, the channel estimation cost is reflected on the EE metric by including its impact in the signal-to-noise ratio term and in the energy consumption during the channels estimation phase. Based on the formulated EE metric, we propose an adaptive power allocation algorithm to maximize the EE of the proposed opportunistic amplify-andforward system with channel estimation. Furthermore, we study the impact of the estimation parameters on the proposed system via simulation examples.

  19. [The CSI effect and its impact on the perceptions of forensic science experts' work].

    Science.gov (United States)

    Stojer, Joanna

    2011-01-01

    The issue that has been analyzed in this work is the potential effect of crime films and TV series on people's perceptions of forensic medicine and science, and especially on the forming of expectations towards forensic science experts. This syndrome is being called the "CSI effect" after the popular franchise Crime Scene Investigation (CSI). Questionnaire surveys that have been conducted included "experts": 50 experts in various specialities, 77 prosecutors, 119 judges, 64 lay judges, 161 police staff and 80 members of general public. In-depth interviews have been conducted with 20 police staff, and also a focus group has been carried out with 15 law students. In the opinion of the respondents, people's perceptions and expectations of forensic science--as it can be observed during criminal trials--are largely inflated by the entertainment media. Among the surveyed persons, the category that declares watching crime series most rarely, is forensic science experts. Around half of the surveyed experts pointed out to excessive expectations towards they work instigated by TV crime series. The most common expectations towards forensic medicine experts are: immediate conclusiveness of post mortem examinations (going as far as indicating the cause of death at the crime scene), precision of death time estimation and a routine use of sophisticated methods known from TV.

  20. CSI-EPT: A Contrast Source Inversion Approach for Improved MRI-Based Electric Properties Tomography.

    Science.gov (United States)

    Balidemaj, Edmond; van den Berg, Cornelis A T; Trinks, Johan; van Lier, Astrid L H M W; Nederveen, Aart J; Stalpers, Lukas J A; Crezee, Hans; Remis, Rob F

    2015-09-01

    Electric properties tomography (EPT) is an imaging modality to reconstruct the electric conductivity and permittivity inside the human body based on B1(+) maps acquired by a magnetic resonance imaging (MRI) system. Current implementations of EPT are based on the local Maxwell equations and assume piecewise constant media. The accuracy of the reconstructed maps may therefore be sensitive to noise and reconstruction errors occur near tissue boundaries. In this paper, we introduce a multiplicative regularized CSI-EPT method (contrast source inversion-electric properties tomography) where the electric tissue properties are retrieved in an iterative fashion based on a contrast source inversion approach. The method takes the integral representations for the electromagnetic field as a starting point and the tissue parameters are obtained by iteratively minimizing an objective function which measures the discrepancy between measured and modeled data and the discrepancy in satisfying a consistency equation known as the object equation. Furthermore, the objective function consists of a multiplicative Total Variation factor for noise suppression during the reconstruction process. Finally, the presented implementation is able to simultaneously include more than one B1(+) data set acquired by complementary RF excitation settings. We have performed in vivo simulations using a female pelvis model to compute the B1(+) fields. Three different RF excitation settings were used to acquire complementary B1(+) fields for an improved overall reconstruction. Numerical results illustrate the improved reconstruction near tissue boundaries and the ability of CSI-EPT to reconstruct small tissue structures.

  1. Novel Control Strategy for VSI and CSI Active Filters and Comparing These Two Types of Filters

    Directory of Open Access Journals (Sweden)

    Gholam Reza Arab

    2014-10-01

    Full Text Available Recently to eliminate the harmonics and improve the power factor of the power networks, much attention has been attracted to active filters. The advantages of these filters are lower volume and their better compensating characteristics than the passive filters. In conventional sliding mode controllers, the source current waveform is fluctuated in near to zero values. In this paper, using a new sliding technique, lower Total Harmonic Distortion (THD in source current is obtained and the current waveform is improved. As well as, two novel control strategies for two types of active filters, VSI and CSI is proposed and then these two types of filters are compared to reduce THD value of source current.The proposed controlled strategies are simulated by MATLAB/Simulink. The Simulation results confirm that the proposed strategies reduce the THD of source current more than other strategies, and active filter based on CSI has a better performance than active filter based on VSI with a dead time area (for avoiding short circuit of the source in high powers.

  2. Fission product behavior in high-temperature water: CsI vs MoO4

    Science.gov (United States)

    Kanjana, K.; Silva, K.; Channuie, J.

    2017-09-01

    Fission product behaviors of Cs, a major element released in a severe nuclear accident, still remain unclear. The question frequently addressed is whether Cs released will be in the form of Cs2MoO4 or CsOH. This is a challenging issue since it has been demonstrated that the reaction between Cs2MoO4 and water leading to CsOH production is thermodynamically favored. The present research aims at investigation of CsOH generation through this chemical channel. A high-temperature setup with a flow system based on the cooling system of a water-cooled nuclear reactor has been assembled. The reaction between aqueous solutions of CsI and Na2MoO4 in a high-corrosion-resistant hot cell (Hastelloy) has been studied up to 80 °C in deoxygenated system. The products have been characterized using FTIR and XRD. The results have shown that there is no reaction between CsI and Na2MoO4 under the experimental conditions.

  3. Sexualidad violenta en el cine de Kim Ki-duk

    Directory of Open Access Journals (Sweden)

    Daniel Muñoz Ruiz

    2011-07-01

    Full Text Available En sus más de 110 años de vida el cine ha representado la sexualidad humana en todas sus modalidades y desde los más variados puntos de vista. El cine de Kim Ki-duk ha sorprendido y escandalizado al público por su crudeza y, a veces, excesiva violencia. El director surcoreano ha explorado a lo largo de su filmografía el tema del sexo siempre desde puntos de vista dramáticos y hasta truculentos. En sus películas la mayoría de las relaciones sexuales carecen de amor y afecto. Nunca son placenteras. La violación, la prostitución, la violencia de género y las frustraciones sexuales son temas recurrentes en su cine.

  4. Modelling refrigerant distribution in minichannel evaporators

    DEFF Research Database (Denmark)

    Brix, Wiebke

    distribution and on the cooling capacity of the evaporator. A one dimensional, steady state model of a minichannel evaporator is used for the study. An evaporator consisting of two multiport minichannels in parallel is used as a test case and two different refrigerants, R134a and R744 (CO2), are applied...... in the numerical experiments using the test case evaporator. The results show that the reduction in cooling capacity due to non-uniform airflow and non-uniform liquid and vapour distribution is generally larger when using R134a than when using CO2 as refrigerant. Comparing the capacity reductions with reductions......This thesis is concerned with numerical modelling of flow distribution in a minichannel evaporator for air-conditioning. The study investigates the impact of non-uniform airflow and non-uniform distribution of the liquid and vapour phases in the inlet manifold on the refrigerant mass flow...

  5. Multi-leg heat pipe evaporator

    Science.gov (United States)

    Alario, J. P.; Haslett, R. A.

    1986-04-01

    A multileg heat pipe evaporator facilitates the use and application of a monogroove heat pipe by providing an evaporation section which is compact in area and structurally more compatible with certain heat exchangers or heat input apparatus. The evaporation section of a monogroove heat pipe is formed by a series of parallel legs having a liquid and a vapor channel and a communicating capillary slot therebetween. The liquid and vapor channels and interconnecting capillary slots of the evaporating section are connected to the condensing section of the heat pipe by a manifold connecting liquid and vapor channels of the parallel evaporation section legs with the corresponding liquid and vapor channels of the condensing section.

  6. Contribution of impervious surfaces to urban evaporation

    Science.gov (United States)

    Ramamurthy, P.; Bou-Zeid, E.

    2014-04-01

    Observational data and the Princeton urban canopy model, with its detailed representation of urban heterogeneity and hydrological processes, are combined to study evaporation and turbulent water vapor transport over urban areas. The analyses focus on periods before and after precipitation events, at two sites in the Northeastern United States. Our results indicate that while evaporation from concrete pavements, building rooftops, and asphalt surfaces is discontinuous and intermittent, overall these surfaces accounted for nearly 18% of total latent heat fluxes (LE) during a relatively wet 10 day period. More importantly, these evaporative fluxes have a significant impact on the urban surface energy balance, particularly during the 48 h following a rain event when impervious evaporation is the highest. Thus, their accurate representation in urban models is critical. Impervious evaporation after rainfall is also shown to correlate the sources of heat and water at the earth surface, resulting in a conditional scalar transport similarity over urban terrain following rain events.

  7. Study of a pure CsI crystal readout by APD for Belle II end cap ECL upgrade

    Energy Technology Data Exchange (ETDEWEB)

    Jin, Y., E-mail: jin@hep.phys.s.u-tokyo.ac.jp [Department of Physics, the University of Tokyo, 7-3-1 Hongo Bunkyo-ku, Tokyo 113-0033 (Japan); Aihara, H. [Department of Physics, the University of Tokyo, 7-3-1 Hongo Bunkyo-ku, Tokyo 113-0033 (Japan); Borshchev, O.V. [Enikolopov Institute of Synthetic Polymeric Materials of the Russian Academy of Sciences, Profsoyuznaya st. 70, Moscow 117393 (Russian Federation); Epifanov, D.A. [Department of Physics, the University of Tokyo, 7-3-1 Hongo Bunkyo-ku, Tokyo 113-0033 (Japan); Ponomarenko, S.A.; Surin, N.M. [Enikolopov Institute of Synthetic Polymeric Materials of the Russian Academy of Sciences, Profsoyuznaya st. 70, Moscow 117393 (Russian Federation)

    2016-07-11

    A scintillation counter consisting of a pure CsI crystal and avalanche photodiodes (Hamamatsu APD S8664-55 and S8664-1010) has been studied for the upgrade of the end cap electromagnetic calorimeter of Belle II detector. An essential increase of the light output was achieved with wavelength shifters based on nanostructured organosilicon luminophores. - Highlights: • A scintillation counter consisting of a pure CsI crystal and avalanche photodiodes has been studied. • The equivalent noise charge and equivalent noise energy of the counter have been measured. • An essential increase of the light output was achieved with wavelength shifters.

  8. Optimal Power Allocation for CC-HARQ-based Cognitive Radio with Statistical CSI in Nakagami Slow Fading Channels

    Science.gov (United States)

    Xu, Ding; Li, Qun

    2017-01-01

    This paper addresses the power allocation problem for cognitive radio (CR) based on hybrid-automatic-repeat-request (HARQ) with chase combining (CC) in Nakagamimslow fading channels. We assume that, instead of the perfect instantaneous channel state information (CSI), only the statistical CSI is available at the secondary user (SU) transmitter. The aim is to minimize the SU outage probability under the primary user (PU) interference outage constraint. Using the Lagrange multiplier method, an iterative and recursive algorithm is derived to obtain the optimal power allocation for each transmission round. Extensive numerical results are presented to illustrate the performance of the proposed algorithm.

  9. Performance of falling film plate evaporators in reconstructed multiple-effect evaporation station in sugar factory

    Directory of Open Access Journals (Sweden)

    Zavargo Zoltan Z.

    2006-01-01

    Full Text Available General trend of free trade in regional level as well as in the direction of European Union has motivated sugar factories located in Serbia to invest into technologies that are more efficient in order to make their products more competitive at the markets in Europe. The aim of this work was to evaluate effects of falling film plate evaporators on the energy consumption of evaporation plant, as well as to validate performance of this type of evaporators. It was found that this type of evaporator decreased energy requirements and in the same time evaporation process was more effective due to high values of heat transfer coefficients. .

  10. Study on the effect of deposition rate and concentration of Eu on the fluorescent lifetime of CsI: Tl thin film

    Energy Technology Data Exchange (ETDEWEB)

    Xie, Yijun; Guo, Lina [University of Electronic Science and Technology of China, State Key Laboratory of Electronic Thin Films and Integrated Devices, School of Optoelectronic Information, Chengdu 610054 (China); Liu, Shuang, E-mail: shuangliu@uestc.edu.cn [University of Electronic Science and Technology of China, State Key Laboratory of Electronic Thin Films and Integrated Devices, School of Optoelectronic Information, Chengdu 610054 (China); Wang, Qianfeng; Zhang, Shangjian; Liu, Yong [University of Electronic Science and Technology of China, State Key Laboratory of Electronic Thin Films and Integrated Devices, School of Optoelectronic Information, Chengdu 610054 (China); Zhong, Zhiyong [University of Electronic Science and Technology of China, State Key Laboratory of Electronic Thin Films and Integrated Devices, Chengdu 610054 (China)

    2017-06-21

    Although there are many new scintillators being developed recently, CsI: Tl is still very efficient among them. The fluorescent lifetime is a very important parameter of CsI: Tl thin film and two series of experiments have been conducted to learn about it. Our experiments, however, have demonstrated that the deposition rate and the codoping of Eu{sup 2+} will significantly influence its fluorescent lifetime. In order to increase the efficiency of the imaging system, we intend to obtain a higher fluorescent lifetime for CsI: Tl thin film by controlling these two conditions. - Highlights: • We used vacuum vapor deposition method to grow the high-quality thin films. • The relationship between the deposition rate and the fluorescent lifetime of CsI: Tl thin film was tested. • Concentration of Eu on fluorescent lifetime of the CsI: Tl thin film was studied.

  11. Effective methods for the measurement of CsI cluster ions using MALDI-MS with suitable solvent combinations and additives.

    Science.gov (United States)

    Mochizuki, Shunsuke

    2014-11-01

    A method to measure CsI cluster ions ((CsI)(n)Cs(+), (CsI)(n)I(-)) from CsI samples in matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) was developed with a 2-[(2E)-3-(4-tert-butylphenyl)-2-methylprop-2-enylidene] malononitrile (DCTB) matrix and additives. Solvent combinations in which the CsI and DCTB solutions were miscible were effective in detecting CsI cluster ions at a mass range of over m/z 2000 and are associated with a characteristic spread of DCTB within the CsI/DCTB mixture. The addition of saccharides or sugar alcohols to the CsI/DCTB mixture improved the DCTB distribution and widened the mass distribution of CsI cluster ions up to m/z 10,000 in the linear mode. Copyright © 2014 John Wiley & Sons, Ltd.

  12. Standardizing evaluation of sarcoma proliferation- higher Ki-67 expression in the tumor periphery than the center

    DEFF Research Database (Denmark)

    Fernebro, J; Engellau, J; Persson, A

    2007-01-01

    Ki-67 staining regarding optimal cut-off levels, selection of tumor areas, and the number of tumor cells to evaluate. We assessed the impact of targeting peripheral versus central tumor areas using tissue microarray-based staining for Ki-67 throughout the tumor diameter in 25 leiomyosarcomas. In 18...

  13. Ki-67 marker useful for classification of malignant invasive ductal breast cancer

    Directory of Open Access Journals (Sweden)

    Irmawati Hassan

    2015-12-01

    The study showed that invasive ductal breast cancer with high Ki-67 index was significantly associated with high grade of malignacy. The high Ki-67 marker index can be used for classification of the grade of malignancy of invasive ductal breast cancer.

  14. 242-A evaporator safety analysis report

    Energy Technology Data Exchange (ETDEWEB)

    CAMPBELL, T.A.

    1999-05-17

    This report provides a revised safety analysis for the upgraded 242-A Evaporator (the Evaporator). This safety analysis report (SAR) supports the operation of the Evaporator following life extension upgrades and other facility and operations upgrades (e.g., Project B-534) that were undertaken to enhance the capabilities of the Evaporator. The Evaporator has been classified as a moderate-hazard facility (Johnson 1990). The information contained in this SAR is based on information provided by 242-A Evaporator Operations, Westinghouse Hanford Company, site maintenance and operations contractor from June 1987 to October 1996, and the existing operating contractor, Waste Management Hanford (WMH) policies. Where appropriate, a discussion address the US Department of Energy (DOE) Orders applicable to a topic is provided. Operation of the facility will be compared to the operating contractor procedures using appropriate audits and appraisals. The following subsections provide introductory and background information, including a general description of the Evaporator facility and process, a description of the scope of this SAR revision,a nd a description of the basic changes made to the original SAR.

  15. Towards a rational definition of potential evaporation

    Directory of Open Access Journals (Sweden)

    J.-P. Lhommel

    1997-01-01

    Full Text Available The concept of potential evaporation is defined on the basis of the following criteria: (i it must establish an upper limit to the evaporation process in a given environment (the term 'environment' including meteorological and surface conditions, and (ii this upper limit must be readily calculated from measured input data. It is shown that this upper limit is perfectly defined and is given by the Penman equation, applied with the corresponding meteorological data (incoming radiation and air characteristics measured at a reference height and the appropriate surface characteristics (albedo, roughness length, soil heat flux. Since each surface has its own potential evaporation, a function of its own surface characteristics, it is useful to define a reference potential evaporation as a short green grass completely shading the ground. Although the potential evaporation from a given surface is readily calculated from the Penman equation, its physical significance or interpretation is not so straightforward, because it represents only an idealized situation, not a real one. Potential evaporation is the evaporation from this surface, when saturated and extensive enough to obviate any effect of local advection, under the same meteorological conditions. Due to the feedback effects of evaporation on air characteristics, it does not represent the 'real' evaporation (i.e. the evaporation which could be physically observed in the real world from such an extensive saturated surface in these given meteorological conditions (if this saturated surface were substituted for an unsaturated one previously existing. From a rigorous standpoint, this calculated potential evaporation is not physically observable. Nevertheless, an approximate representation can be given by the evaporation from a limited saturated area, the dimension of which depends on the height of measurement of the air characteristics used as input in the Penman equation. If they are taken at a height

  16. On the evaporation of ammonium sulfate solution

    Energy Technology Data Exchange (ETDEWEB)

    Drisdell, Walter S.; Saykally, Richard J.; Cohen, Ronald C.

    2009-07-16

    Aqueous evaporation and condensation kinetics are poorly understood, and uncertainties in their rates affect predictions of cloud behavior and therefore climate. We measured the cooling rate of 3 M ammonium sulfate droplets undergoing free evaporation via Raman thermometry. Analysis of the measurements yields a value of 0.58 {+-} 0.05 for the evaporation coefficient, identical to that previously determined for pure water. These results imply that subsaturated aqueous ammonium sulfate, which is the most abundant inorganic component of atmospheric aerosol, does not affect the vapor-liquid exchange mechanism for cloud droplets, despite reducing the saturation vapor pressure of water significantly.

  17. Upgrading existing evaporators to reduce energy consumption

    Energy Technology Data Exchange (ETDEWEB)

    1977-01-01

    This manual is intended to assist the evaporator engineer who will be performing the technical and economic analyses to determine the most suitable evaporator upgrading technique for his particular plant. Information is included on potentials for upgrading evaporators; correctable operating factors; heat recovery and other improvements in energy use with minor capital investments; upgrading through major capital investments; guidelines for formulating an upgrading program; and new technologies encompassing advanced designs, use of solar and low-grade heat sources, and heat transfer enhancement. A 36 item bibliography is included. (LCL)

  18. Enhanced Evaporation and Condensation in Tubes

    Science.gov (United States)

    Honda, Hiroshi

    A state-of-the-art review of enhanced evaporation and condensation in horizontal microfin tubes and micro-channels that are used for air-conditioning and refrigeration applications is presented. The review covers the effects of flow pattern and geometrical parameters of the tubes on the heat transfer performance. Attention is paid to the effect of surface tension which leads to enhanced evaporation and condensation in the microfin tubes and micro-channels. A review of prior efforts to develop empirical correlations of the heat transfer coefficient and theoretical models for evaporation and condensation in the horizontal microfin tubes and micro-channels is also presented.

  19. Psychometric Evaluation of a Coping Strategies Inventory Short-Form (CSI-SF in the Jackson Heart Study Cohort

    Directory of Open Access Journals (Sweden)

    Herman Taylor

    2007-12-01

    Full Text Available This study sought to establish the psychometric properties of a Coping Strategies Inventory Short Form (CSISF by examining coping skills in the Jackson Heart Study cohort. We used exploratory and confirmatory factor analysis, Pearson’s correlation, and Cronbach Alpha to examine reliability and validity in the CSI-SF that solicited responses from 5302 African American men and women between the ages of 35 and 84. One item was dropped from the 16-item CSI-SF, making it a 15-item survey. No significant effects were found for age and gender, strengthening the generalizability of the CSI-SF. The internal consistency reliability analysis revealed reliability between alpha = 0.58-0.72 for all of the scales, and all of the fit indices used to examine the CSI-SF provided support for its use as an adequate measure of coping. This study provides empirical support for utilizing this instrument in future efforts to understand the role of coping in moderating health outcomes.

  20. Novel Robust Optimization and Power Allocation of Time Reversal-MIMO-UWB Systems in an Imperfect CSI

    Directory of Open Access Journals (Sweden)

    Sajjad Alizadeh

    2013-03-01

    Full Text Available Time Reversal (TR technique is an attractive solution for a scenario where the transmission system employs low complexity receivers with multiple antennas at both transmitter and receiver sides. The TR technique can be combined with a high data rate MIMO-UWB system as TR-MIMO-UWB system. In spite of TR's good performance in MIMO-UWB systems, it suffers from performance degradation in an imperfect Channel State Information (CSI case. In this paper, at first a robust TR pre-filter is designed together with a MMSE equalizer in TR-MIMO-UWB system where is robust against channel imperfection conditions. We show that the robust pre-filter optimization technique, considerably improves the BER performance of TR-MIMO-UWB system in imperfect CSI, where temporal focusing of the TR technique is kept, especially for high SNR values. Then, in order to improve the system performance more than ever, a power loading scheme is developed by minimizing the average symbol error rate in an imperfect CSI. Numerical and simulation results are presented to confirm the performance advantage attained by the proposed robust optimization and power loading in an imperfect CSI scenario.

  1. 78 FR 41911 - Foreign-Trade Zone 39-Dallas-Fort Worth, Texas; CSI Calendering, Inc. (Rubber Coated Textile...

    Science.gov (United States)

    2013-07-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Foreign-Trade Zones Board Foreign-Trade Zone 39--Dallas-Fort Worth, Texas; CSI Calendering, Inc. (Rubber Coated Textile Fabric); Arlington, Texas On March 4, 2013, the Dallas/Fort Worth International Airport Board, grantee of FTZ 39, submitted a...

  2. Psychometric evaluation of a Coping Strategies Inventory Short-Form (CSI-SF) in the Jackson Heart Study cohort.

    Science.gov (United States)

    Addison, Clifton C; Campbell-Jenkins, Brenda W; Sarpong, Daniel F; Kibler, Jeffery; Singh, Madhu; Dubbert, Patricia; Wilson, Gregory; Payne, Thomas; Taylor, Herman

    2007-12-01

    This study sought to establish the psychometric properties of a Coping Strategies Inventory Short Form (CSISF) by examining coping skills in the Jackson Heart Study cohort. We used exploratory and confirmatory factor analysis, Pearson's correlation, and Cronbach Alpha to examine reliability and validity in the CSI-SF that solicited responses from 5302 African American men and women between the ages of 35 and 84. One item was dropped from the 16-item CSI-SF, making it a 15-item survey. No significant effects were found for age and gender, strengthening the generalizability of the CSI-SF. The internal consistency reliability analysis revealed reliability between alpha = 0.58-0.72 for all of the scales, and all of the fit indices used to examine the CSI-SF provided support for its use as an adequate measure of coping. This study provides empirical support for utilizing this instrument in future efforts to understand the role of coping in moderating health outcomes.

  3. Charter Schools Indicators: A Report from the Center on Educational Governance University of Southern California. CSI-USC 2010

    Science.gov (United States)

    Center on Educational Governance, 2010

    2010-01-01

    CSI-USC continues to make sense of what the California statewide data system provides. This fourth annual report gauges multiple measures of academic and financial performance, probing well beyond mere test scores. Ratings in familiar green, yellow, and red cover four areas: financial resources and investment, school quality, student performance…

  4. An indirect method for in vivo T2 mapping of [1-(13) C] pyruvate using hyperpolarized (13) C CSI.

    Science.gov (United States)

    Joe, Eunhae; Lee, Hansol; Lee, Joonsung; Yang, Seungwook; Choi, Young-Suk; Wang, Eunkyung; Song, Ho-Taek; Kim, Dong-Hyun

    2017-05-01

    An indirect method for in vivo T2 mapping of (13) C-labeled metabolites using T2 and T2 * information of water protons obtained a priori is proposed. The T2 values of (13) C metabolites are inferred using the relationship to T2 ' of coexisting (1) H and the T2 * of (13) C metabolites, which is measured using routine hyperpolarized (13) C CSI data. The concept is verified with phantom studies. Simulations were performed to evaluate the extent of T2 estimation accuracy due to errors in the other measurements. Also, bias in the (13) C T2 * estimation from the (13) C CSI data was studied. In vivo experiments were performed from the brains of normal rats and a rat with C6 glioma. Simulation results indicate that the proposed method provides accurate and unbiased (13) C T2 values within typical experimental settings. The in vivo studies found that the estimated T2 of [1-(13) C] pyruvate using the indirect method was longer in tumor than in normal tissues and gave values similar to previous reports. This method can estimate localized T2 relaxation times from multiple voxels using conventional hyperpolarized (13) C CSI and can potentially be used with time resolved fast CSI. Copyright © 2017 John Wiley & Sons, Ltd.

  5. Ki67 expression in breast cancer. Correlation with prognostic markers and clinicopathological parameters in Saudi patients

    Directory of Open Access Journals (Sweden)

    Mohamed A. Elkablawy

    2016-02-01

    Full Text Available Objectives: To evaluate Ki67 immunoexpression pattern in Saudi breast cancer (BC patients and investigate any possible predictive or prognostic value for Ki67. Methods: This is a retrospective study designed to quantitatively assess the Ki67 proliferative index (PI in retrieved paraffin blocks of 115 Saudi BC patients diagnosed between January 2005 and March 2015 at the Department of Pathology, King Fahd Hospital, Al Madinah Al Munawarah, Kingdom of Saudi Arabia. The Ki67 PI was correlated with individual and combined immunoprofile data of estrogen receptor (ER, progesterone receptor (PR, and human epidermal growth factor receptor 2 (HER2/neu with their clinicopathological parameters. Results: Ki67 immunoreactivity was highly expressed (greater than 25% of the tumor cells were positive in 85 (73.9% patients. The Ki67 PI was significantly associated with poor prognostic clinicopathological parameters including old age (p less than 0.02, high tumor grade (p less than 0.01, lymph node metastasis (p less than 0.001, and Her-2/neu positivity (p less than 0.009. However, the association with ER positivity, PR positivity, tumor size, and lymphovascular invasion were not statistically significant. The Ki67 PI was significantly associated with BC molecular subtypes that were Her2/neu positive (luminal B and HER-2 subtypes compared with the Her2/neu negative (luminal A subtype (p less than 0.04. Conclusion: The Ki67 PI is significantly higher in Saudi BC patients comparing with the reported literature. Ki67 PI was highest in the HER-2 and luminal-B molecular subtypes. Along with other prognostic indicators, Ki67 PI may be useful in predicting prognosis and management of Saudi BC patients.

  6. Variable Ki67 proliferative index in 65 cases of nodular fasciitis, compared with fibrosarcoma and fibromatosis

    Science.gov (United States)

    2013-01-01

    Abstract Nodular fasciitis is the most common pseudosarcomatous lesion of soft tissue. Ki67 was considered as a useful marker for distinguishing some benign and malignant lesions. To study the usefulness of Ki67 in diagnosis of nodular fasciitis, the expression of Ki67 was examined by using immunostaining in 65 nodular fasciitis specimens, 15 desmoid fibromatosis specimens and 20 fibrosarcoma specimens. The results showed that there was a variable Ki67 index in all 65 cases of nodular fasciitis, and the mean labeling index was 23.71±15.01%. In majority (70.77%) of all cases,the index was ranged from 10% to 50%, in 6.15% (4/65) of cases the higher Ki67 index (over 50%) could be seen. The Ki67 proliferative index was closely related to duration of lesion, but not to age distribution, lesion size, sites of lesions and gender. Moreover, the mean proliferative index in desmoid fibromatosis and fibrosarcoma was 3.20±1.26% and 26.15±3.30% respectively. The mean Ki67 index of nodular fasciitis was not significantly lower than fibrosarcoma, but higher than desmoid fibromatosis. The variable and high Ki67 index in nodular fasciitis may pose a diagnostic challenge. We should not misdiagnose nodular fasciitis as a sarcoma because of its high Ki67 index. The recurrence of nodular fasciitis is rare; and the utility of Ki67 immunostaining may be not suitable for recurrence assessment in nodular fasciitis. Virtual slides The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/4782335818876666 PMID:23531088

  7. CSI Index Of Customer's Satisfaction Applied In The Area Of Public Transport

    Science.gov (United States)

    Poliaková, Adela

    2015-06-01

    In Western countries, the new visions are applied in quality control for an integrated public transport system. Public transport puts the customer at the centre of our decision making in achieving customer satisfaction with provided service. Sustainable surveys are kept among customers. A lot of companies are collecting huge databases containing over 30,000 voices of customers, which demonstrates the current satisfaction levels across the public transport service. Customer satisfaction with a provided service is a difficult task. In this service, the quality criteria are not clearly defined, and it is therefore difficult to define customer satisfaction. The paper introduces a possibility of CSI index application in conditions of the Slovak Republic transport area.

  8. Progress in the medicinal chemistry of silicon: C/Si exchange and beyond.

    Science.gov (United States)

    Fujii, Shinya; Hashimoto, Yuichi

    2017-04-01

    Application of silyl functionalities is one of the most promising strategies among various 'elements chemistry' approaches for the development of novel and distinctive drug candidates. Replacement of one or more carbon atoms of various biologically active compounds with silicon (so-called sila-substitution) has been intensively studied for decades, and is often effective for alteration of activity profile and improvement of metabolic profile. In addition to simple C/Si exchange, several novel approaches for utilizing silicon in medicinal chemistry have been suggested in recent years, focusing on the intrinsic differences between silicon and carbon. Sila-substitution offers great potential for enlarging the chemical space of medicinal chemistry, and provides many options for structural development of drug candidates.

  9. CSI: Dognapping workshop : an outreach experiment designed to produce students that are hooked on science.

    Energy Technology Data Exchange (ETDEWEB)

    Boyle, Timothy J.; Gorman, Anna K.; Pratt, Harry D., III; Hernandez-Sanchez, Bernadette A.; Lambert, Timothy N.; Ottley, Leigh Anna M.; Baros, Christina Marie

    2008-04-01

    The CSI: Dognapping Workshop is a culmination of the more than 65 Sandian staff and intern volunteers dedication to exciting and encouraging the next generation of scientific leaders. This 2 hour workshop used a 'theatrical play' and 'hands on' activities that was fun, exciting and challenging for 3rd-5th graders while meeting science curriculum standards. In addition, new pedagogical methods were developed in order to introduce nanotechnology to the public. Survey analysis indicated that the workshop had an overall improvement and positive impact on helping the students to understand concepts from materials science and chemistry as well as increased our interaction with the K-5 community. Anecdotal analyses showed that this simple exercise will have far reaching impact with the results necessary to maintain the United States as the scientific leader in the world. This experience led to the initiation of over 100 Official Junior Scientists.

  10. On the secrecy capacity of the broadcast wiretap channel with limited CSI feedback

    KAUST Repository

    Hyadi, Amal

    2016-10-27

    In this paper, we investigate the problem of secure broadcasting over block-fading channels with limited channel knowledge at the transmitter. More particularly, we analyze the effect of having imperfect channel state information (CSI) via a finite rate feedback on the throughput of a broadcast channel where the transmission is intended for multiple legitimate receivers in the presence of an eavesdropper. First, we partially characterize the ergodic secrecy capacity of the system when the source broadcasts the same information to all the receivers, i.e., common message transmission. Then, we look at the independent messages case, where the transmitter broadcasts multiple independent messages to the legitimate receivers. For this case, we present lower and upper bounds on the ergodic secrecy sum-capacity. In both scenarios, we show that the proposed lower and upper bounds coincide asymptotically as the capacity of the feedback links becomes large, hence, fully characterizing the secrecy capacity in this case.

  11. 3D Imaging of Dielectric Objects Buried under a Rough Surface by Using CSI

    Directory of Open Access Journals (Sweden)

    Evrim Tetik

    2015-01-01

    Full Text Available A 3D scalar electromagnetic imaging of dielectric objects buried under a rough surface is presented. The problem has been treated as a 3D scalar problem for computational simplicity as a first step to the 3D vector problem. The complexity of the background in which the object is buried is simplified by obtaining Green’s function of its background, which consists of two homogeneous half-spaces, and a rough interface between them, by using Buried Object Approach (BOA. Green’s function of the two-part space with planar interface is obtained to be used in the process. Reconstruction of the location, shape, and constitutive parameters of the objects is achieved by Contrast Source Inversion (CSI method with conjugate gradient. The scattered field data that is used in the inverse problem is obtained via both Method of Moments (MoM and Comsol Multiphysics pressure acoustics model.

  12. Testing and Installation of a High Efficiency CsI Scintillator Array

    Science.gov (United States)

    Viscariello, Natalie; Casarotto, Stuart; Frank, Nathan; Smith, Jenna; Thoennessen, Michael

    2011-10-01

    Experiments on neutron-rich nuclei have identified changes to the structure of nuclei far from stability. The Sweeper-MoNA- LISA facility at the National Superconducting Cyclotron Laboratory (NSCL), located at Michigan State University, is used for performing experiments on neutron-rich nuclei. Currently, these experiments are limited to the mass region below neon due to the resolution of the charged fragment detectors, which limit the isotope separation. The resolution of the system will be improved with changes to the setup, primarily due to a new scintillator array. The new array will consist of twenty-five sodium-doped CsI crystals arranged in a 5 × 5 configuration. The array will be used to measure the kinetic energy of charged fragments with energies in the GeV range. The improved resolution will allow experiments of unbound systems above neon. The testing and assembly of the detector array will be presented.

  13. Near-infrared ultrabroadband luminescence spectra properties of subvalent bismuth in CsI halide crystals.

    Science.gov (United States)

    Su, Liangbi; Zhao, Hengyu; Li, Hongjun; Zheng, Lihe; Ren, Guohao; Xu, Jun; Ryba-Romanowski, Witold; Lisiecki, Radosław; Solarz, Piotr

    2011-12-01

    We observed two ultrabroadband near-infrared (NIR) luminescence bands around 1.2 and 1.5 μm in as-grown bismuth-doped CsI halide crystals, without additional aftertreatment. Dependence of the NIR emission properties on the excitation wavelength and measurement temperature was studied. Two kinds of NIR active centers of subvalent bismuth and color centers were demonstrated to coexist in Bi:CsI crystal. The eye-safe 1.5 μm emission band with an FWHM of 140 nm and lifetime of 213 μs at room temperature makes Bi:CsI crystal promising in the applications of the ultrafast laser and ultrabroadband amplifier. © 2011 Optical Society of America

  14. Two-way CSI-assisted AF relaying with HPA nonlinearity

    KAUST Repository

    Qi, Jian

    2015-09-11

    In this paper, we investigate half-duplex two-way dual-hop channel state information (CSI)-assisted amplify-andforward (AF) relaying in the presence of high-power amplifier (HPA) nonlinearity at relays. The expression for the end-toend signal-to-noise ratio (SNR) is derived as per the modified system model by taking into account the interference caused by relaying scheme and HPA nonlinearity. The system performance of the considered relaying network is evaluated in terms of average symbol error probability (SEP) in Nakagami-m fading channels, by making use of the moment-generating function (MGF) approach. Numerical results are provided and show the effects of several parameters, such as quadrature amplitude modulation (QAM) order, number of relays, HPA parameters, and Nakagami parameter, on performance. © 2015 IEEE.

  15. Denton E-beam Evaporator #1

    Data.gov (United States)

    Federal Laboratory Consortium — Description:CORAL Name: E-Beam Evap 1This is a dual e-beam/thermal evaporator for the deposition of metal and dielectric thin films. Materials available are: Ag, Al,...

  16. Denton E-beam Evaporator #2

    Data.gov (United States)

    Federal Laboratory Consortium — Description:CORAL Name: E-Beam Evap 2This is an electron gun evaporator for the deposition of metals and dielectrics thin films. Materials available are: Ag, Al, Au,...

  17. Evaporation analysis for Tank SX-104

    Energy Technology Data Exchange (ETDEWEB)

    Barrington, C.A.

    1994-10-01

    Decreases in historical interstitial liquid level measurements in tank SX-104 were compared to predictions of a numerical model based upon diffusion of water through a porous crust. The analysis showed that observed level decreases could be explained by evaporation.

  18. Lattice-Boltzmann simulations of droplet evaporation

    KAUST Repository

    Ledesma-Aguilar, Rodrigo

    2014-09-04

    © the Partner Organisations 2014. We study the utility and validity of lattice-Boltzmann (LB) simulations to explore droplet evaporation driven by a concentration gradient. Using a binary-fluid lattice-Boltzmann algorithm based on Cahn-Hilliard dynamics, we study the evaporation of planar films and 3D sessile droplets from smooth solid surfaces. Our results show that LB simulations accurately reproduce the classical regime of quasi-static dynamics. Beyond this limit, we show that the algorithm can be used to explore regimes where the evaporative and diffusive timescales are not widely separated, and to include the effect of boundaries of prescribed driving concentration. We illustrate the method by considering the evaporation of a droplet from a solid surface that is chemically patterned with hydrophilic and hydrophobic stripes. This journal is

  19. Spacesuit Evaporator-Absorber-Radiator (SEAR) Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This project builds from the work of the first year of effort that successfully integrated the Spacesuit  Water Membrane Evaporator (SWME), developed by the...

  20. The Central Sensitization Inventory (CSI): establishing clinically significant values for identifying central sensitivity syndromes in an outpatient chronic pain sample.

    Science.gov (United States)

    Neblett, Randy; Cohen, Howard; Choi, YunHee; Hartzell, Meredith M; Williams, Mark; Mayer, Tom G; Gatchel, Robert J

    2013-05-01

    Central sensitization (CS) is a proposed physiological phenomenon in which central nervous system neurons become hyperexcitable, resulting in hypersensitivity to both noxious and non-noxious stimuli. The term central sensitivity syndrome (CSS) describes a group of medically indistinct (or nonspecific) disorders, such as fibromyalgia, chronic fatigue syndrome, and irritable bowel syndrome, for which CS may be a common etiology. In a previous study, the Central Sensitization Inventory (CSI) was introduced as a screening instrument for clinicians to help identify patients with a CSS. It was found to have high reliability and validity (test-retest reliability = .82; Cronbach's alpha = .88). The present study investigated a cohort of 121 patients who were referred to a multidisciplinary pain center, which specializes in the assessment and treatment of complex pain and psychophysiological disorders, including CSSs. A large percentage of patients (n = 89, 74%) met clinical criteria for one or more CSSs, and CSI scores were positively correlated with the number of diagnosed CSSs. A receiver operating characteristic analysis determined that a CSI score of 40 out of 100 best distinguished between the CSS patient group and a nonpatient comparison sample (N = 129) (area under the curve = .86, sensitivity = 81%, specificity = 75%). The CSI is a new self-report screening instrument to help identify patients with CSSs, including fibromyalgia. The present study investigated CSI scores in a heterogeneous pain population with a large percentage of CSSs, and a normative nonclinical sample to determine a clinically relevant cutoff value. Copyright © 2013 American Pain Society. Published by Elsevier Inc. All rights reserved.

  1. FY16 ASC ATDM L2 Milestone: PARTISN Research and FleCSI Updates

    Energy Technology Data Exchange (ETDEWEB)

    Womeldorff, Geoffrey Alan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Payne, Joshua Estes [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Bergen, Benjamin Karl [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-09-01

    These are slides for a presentation on PARTISN Research and FleCSI Updates. The following topics are covered: SNAP vs PARTISN, Background Research, Production Code (structural design and changes, kernel design and implementation, lessons learned), NuT IMC Proxy, FleCSI Update (design and lessons learned). It can all be summarized in the following manner: Kokkos was shown to be effective in FY15 in implementing a C++ version of SNAP's kernel. This same methodology was applied to a production IC code, PARTISN. This was a much more complex endeavour than in FY15 for many reasons; a C++ kernel embedded in Fortran, overloading Fortran memory allocations, general language interoperability, and a fully fleshed out production code versus a simplified proxy code. Lessons learned are Legion. In no particular order: Interoperability between Fortran and C++ was really not that hard, and a useful engineering effort. Tracking down all necessary memory allocations for a kernel in a production code is pretty hard. Modifying a production code to work for more than a handful of use cases is also pretty hard. Figuring out the toolchain that will allow a successful implementation of design decisions is quite hard, if making use of "bleeding edge" design choices. In terms of performance, production code concurrency architecture can be a virtual showstopper; being too complex to easily rewrite and test in a short period of time, or depending on tool features which do not exist yet. Ultimately, while the tools used in this work were not successful in speeding up the production code, they helped to identify how work would be done, and provide requirements to tools.

  2. Analysis of the ITER central solenoid insert (CSI) coil stability tests

    Science.gov (United States)

    Savoldi, L.; Bonifetto, R.; Breschi, M.; Isono, T.; Martovetsky, N.; Ozeki, H.; Zanino, R.

    2017-07-01

    At the end of the test campaign of the ITER Central Solenoid Insert (CSI) coil in 2015, after 16,000 electromagnetic (EM) cycles, some tests were devoted to the study of the conductor stability, through the measurement of the Minimum Quench Energy (MQE). The tests were performed by means of an inductive heater (IH), located in the high-field region of the CSI and wrapped around the conductor. The calorimetric calibration of the IH is presented here, aimed at assessing the energy deposited in the conductor for different values of the IH electrical operating conditions. The MQE of the conductor of the ITER CS module 3L can be estimated as ∼200 J ± 20%, deposited on the whole conductor on a length of ∼10 cm (the IH length) in ∼40 ms, at current and magnetic field conditions relevant for the ITER CS operation. The repartition of the energy deposited in the conductor under the IH is computed to be ∼10% in the cable and 90% in the jacket by means of a 3D Finite Elements EM model. It is shown how this repartition implies that the bundle (cable + helium) heat capacity is fully available for stability on the time scale of the tested disturbances. This repartition is used in input to the thermal-hydraulic analysis performed with the 4C code, to assess the capability of the model to accurately reproduce the stability threshold of the conductor. The MQE computed by the code for this disturbance is in good agreement with the measured value, with an underestimation within 15% of the experimental value.

  3. Climatic Controls on Evaporation in Hawaii.

    Science.gov (United States)

    Nullet, Dennis Mcclain

    The primary aims of this dissertation were to identify and explain variation in potential evaporation at different elevations and different exposures on tropical high islands, to provide reference data for modeling evaporation, and to suggest how an evaporation model appropriate for tropical high islands might be developed. The most important contribution of this study was to quantify the importance of advection in controlling the evaporation rate on tropical high islands. Sensible heat advection from the surrounding ocean moderates the evaporation rate at windward coastal sites. This effect ranged, on average, from 0.85 mm/day enhancement in November to 0.71 mm/day suppression in June. Heat advection from land sources increased the evaporation rate by as much as 2.8 mm/day in central Maui. Large-scale subsidence over the Hawaiian Islands region accounts for an additional source of advection, enhancing evaporation above approximately above 1200 m on the mountain. Preliminary results indicate that this effect increases with elevation in conjunction with the night evaporation rate. Cloud patterns over the mountain slopes and optical air mass determine the solar radiation receipt (the primary source of energy for evaporation) pattern which ranged from 85% to 51% of clear-day radiation in summer and 80% to 63% in winter. Insolation declined with elevation over the study site, except above 1200 meters in winter where it increased with elevation. Results of the study indicate that common methods for estimating potential evaporation need to be modified to account for the effect of advection. Temperature and vapor pressure on the mountain can be estimated using rawinsonde data. Net radiation can be mapped from global radiation estimated from modeled clear-day radiation reduced according to a cloudiness index. Ocean advection can he accounted for at the lower elevations by simply adding a monthly modifier based on results presented in the study. Land advection can be

  4. Evaluating Evaporation with Satellite Thermal Data.

    Science.gov (United States)

    1987-11-01

    and Executive S~ury: se attachd Water surface tmiera e can be obtaind fron satellite Ueml remote senir. landsat and other satellite s emitted thermal...values with the lake’s surface temp ~eratuire by performing a linear regression to get an equation, or model, that defines the evaporation for a given...infrared radiation on a regular basis over uxfd of the earth’s surface . Evaporation is acccmplished by the net txansport of mas from the water surface

  5. High-Capacity Heat-Pipe Evaporator

    Science.gov (United States)

    Oren, J. A.; Duschatko, R. J.; Voss, F. E.; Sauer, L. W.

    1989-01-01

    Heat pipe with cylindrical heat-input surface has higher contact thermal conductance than one with usual flat surface. Cylindrical heat absorber promotes nearly uniform flow of heat into pipe at all places around periphery of pipe, helps eliminate hotspots on heat source. Lugs in aluminum pipe carry heat from outer surface to liquid oozing from capillaries of wick. Liquid absorbs heat, evaporates, and passes out of evaporator through interlug passages.

  6. Ideološki učinki mestne prenove

    Directory of Open Access Journals (Sweden)

    Blaž Križnik

    2005-01-01

    Full Text Available V prispevku želimo pokazati nekatere družbene posledice prehoda industrijskega mesta v postindustrijsko, kot primer bomo pogledali preobrazbo soseske Poblenou v Barceloni. Najprej bomo ugotovili, da je mesto lahko nosilec ideoloških sporočil in da ima produkcija mestnega prostora vedno tudi neposredne ideološke učinke. Pokazali bomo, da integracija barcelonske ekonomije v globalno ekonomijo in njena strukturna preobrazba pomembno vplivata na preobrazbo soseske Poblenou ter tako neposredno določata vsakdanjo izkušnjo mesta tamkaj živečih prebivalcev. Vendar barcelonski mestni oblastniki ekonomsko motivirano preobrazbo prikazujejo kot nujno prenovo »problematične soseske«, ki da je v interesu njenih prebivalcev. Prav tu je zato treba kritično premisliti ideološke učinke hegemonističnih reprezentacij mesta ne le kot instrumentov vsiljevanja korporativnih ali birokratskih interesov od zgoraj, ampak tudi kot nosilca normalizacije posameznika in homogenizacije mestnega prebivalstva. Kot primer takšnega vsiljevanja bomo v sklepu navedli primer Kolizeja v Ljubljani.

  7. Mletački kaštel u Zadru

    Directory of Open Access Journals (Sweden)

    Emil Hilje

    2011-12-01

    Full Text Available “Mletački kaštel” u Zadru predstavlja sasvim specifičnu fortifikacijsku strukturu. Iako uklopljen u sustav gradskih zidina, već prvobitnom nakanom pri njegovoj gradnji bio je manje namijenjen obrani samoga grada, a više obrani od grada. Relativno brojni podaci o preuređivanju te utvrde nakon zadarske pobune, sredinom 14. st, a zatim i nakon ponovnog pada Zadra pod vlast Mletačke Republike početkom 15. stoljeća, svjedoče da je cjelokupan sustav utvrđivanja tog dijela gradskih fortifikacija prvenstveno služio u svrhu obrane mletačke vojne posade od eventualnih napada Zadrana, to jest kao sredstvo učvrščivanja i održavanja mletačke vlasti u buntovnom gradu. Posebnu pažnju privlači reljef krilatog lava, simbola Mletačke Republike, ugrađen u pročelje “Malog arsenala”, koji predstavlja jedan od najkvalitetnijih reljefa te vrste u Zadru, a moguće ga je datirati oko sredine 15. stoljeća.

  8. KONSEP PEMIKIRAN PENDIDIKAN MENURUT PAULO FREIRE DAN KI HAJAR DEWANTORO

    Directory of Open Access Journals (Sweden)

    Ahmad Syaikhudin

    2012-06-01

    Full Text Available Abstract: Criticism and alternative education offered by Paulo Freire is very interesting to be used to analyze the problems of education in Indonesia. It must be admitted that the context behind the controversial issue of those educational thought is different from that of Indonesian, however, it must be very suitable. According to Paulo Freire, there should be no dichotomy between the goals of education and educational ways. The goal, the transformation that frees individual to be a real person, should be manifested in the extent to how education must be implemented. The purpose of exemption cannot be separated with the path that frees. In addition, Freire's educational theory remains significant in terms of its role in which education should bring up not only the understanding of the world, but also the transformation of the world. On the other hands, Indonesian national leaders, Ki Hajar Dewantara also has inherited a very important philosophy in our national education, that is ing ngarso sung tulodo, ing madyo mangun karso, tut wuri handayani which means that the front is setting as a good model, the middle is inspiring and in the back provides support.

  9. Fully adiabatic 31P 2D-CSI with reduced chemical shift displacement error at 7 T--GOIA-1D-ISIS/2D-CSI.

    Science.gov (United States)

    Chmelík, M; Kukurová, I Just; Gruber, S; Krššák, M; Valkovič, L; Trattnig, S; Bogner, W

    2013-05-01

    A fully adiabatic phosphorus (31P) two-dimensional (2D) chemical shift spectroscopic imaging sequence with reduced chemical shift displacement error for 7 T, based on 1D-image-selected in vivo spectroscopy, combined with 2D-chemical shift spectroscopic imaging selection, was developed. Slice-selective excitation was achieved by a spatially selective broadband GOIA-W(16,4) inversion pulse with an interleaved subtraction scheme before nonselective adiabatic excitation, and followed by 2D phase encoding. The use of GOIA-W(16,4) pulses (bandwidth 4.3-21.6 kHz for 10-50 mm slices) reduced the chemical shift displacement error in the slice direction ∼1.5-7.7 fold, compared to conventional 2D-chemical shift spectroscopic imaging with Sinc3 selective pulses (2.8 kHz). This reduction was experimentally demonstrated with measurements of an MR spectroscopy localization phantom and with experimental evaluation of pulse profiles. In vivo experiments in clinically acceptable measurement times were demonstrated in the calf muscle (nominal voxel volume, 5.65 ml in 6 min 53 s), brain (10 ml, 6 min 32 s), and liver (8.33 ml, 8 min 14 s) of healthy volunteers at 7 T. High reproducibility was found in the calf muscle at 7 T. In combination with adiabatic excitation, this sequence is insensitive to the B1 inhomogeneities associated with surface coils. This sequence, which is termed GOIA-1D-ISIS/2D-CSI (goISICS), has the potential to be applied in both clinical research and in the clinical routine. Copyright © 2012 Wiley Periodicals, Inc.

  10. Evaporation Heat Transfer of Ammonia and Pressure Drop of Warm Water for Plate Type Evaporator

    Science.gov (United States)

    Kushibe, Mitsuteru; Lkegami, Yasuyuki; Monde, Masanori; Uehara, Haruo

    The performance test of three types of plate type evaporators for spring thermal energy conversion and ocean thermal energy conversion carried out. Ammonia is utilized as working fluid and warm water is utilized as heat source. An empirical correlation is proposed in order to predict the mean evaporation heat transfer coefficient of ammonia and heat transfer coefficient of warm water for plate type evaporators. The mean heat transfer coefficient and friction factor of warm water were compared with other researches.

  11. Sheet Membrane Spacesuit Water Membrane Evaporator

    Science.gov (United States)

    Bue, Grant; Trevino, Luis; Zapata, Felipe; Dillion, Paul; Castillo, Juan; Vonau, Walter; Wilkes, Robert; Vogel, Matthew; Frodge, Curtis

    2013-01-01

    A document describes a sheet membrane spacesuit water membrane evaporator (SWME), which allows for the use of one common water tank that can supply cooling water to the astronaut and to the evaporator. Test data showed that heat rejection performance dropped only 6 percent after being subjected to highly contaminated water. It also exhibited robustness with respect to freezing and Martian atmospheric simulation testing. Water was allowed to freeze in the water channels during testing that simulated a water loop failure and vapor backpressure valve failure. Upon closing the backpressure valve and energizing the pump, the ice eventually thawed and water began to flow with no apparent damage to the sheet membrane. The membrane evaporator also serves to de-gas the water loop from entrained gases, thereby eliminating the need for special degassing equipment such as is needed by the current spacesuit system. As water flows through the three annular water channels, water evaporates with the vapor flowing across the hydrophobic, porous sheet membrane to the vacuum side of the membrane. The rate at which water evaporates, and therefore, the rate at which the flowing water is cooled, is a function of the difference between the water saturation pressure on the water side of the membrane, and the pressure on the vacuum side of the membrane. The primary theory is that the hydrophobic sheet membrane retains water, but permits vapor pass-through when the vapor side pressure is less than the water saturation pressure. This results in evaporative cooling of the remaining water.

  12. Radicals and ions controlling by adjusting the antenna-substrate distance in a-Si:H deposition using a planar ICP for c-Si surface passivation

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, H.P., E-mail: haipzhou@uestc.edu.cn [School of Energy Science and Engineering, University of Electronic Science and Technology of China, 2006 Xiyuan Ave., West High-Tech Zone, Chengdu, Sichuan, 611731 (China); Plasma Sources and Application Center, NIE, and Institute of Advanced Studies, Nanyang Technological University, 637616 (Singapore); Xu, S., E-mail: shuyan.xu@nie.edu.sg [Plasma Sources and Application Center, NIE, and Institute of Advanced Studies, Nanyang Technological University, 637616 (Singapore); Xu, M. [Key Laboratory of Information Materials of Sichuan Province & School of Electrical and Information Engineering, Southwest University for Nationalities, Chengdu, 610041 (China); Xu, L.X.; Wei, D.Y. [Plasma Sources and Application Center, NIE, and Institute of Advanced Studies, Nanyang Technological University, 637616 (Singapore); Xiang, Y. [School of Energy Science and Engineering, University of Electronic Science and Technology of China, 2006 Xiyuan Ave., West High-Tech Zone, Chengdu, Sichuan, 611731 (China); Xiao, S.Q. [Key Laboratory of Advanced Process Control for Light Industry (Ministry of Education), Department of Electronic Engineering, Jiangnan University, Wuxi, 214122 (China)

    2017-02-28

    Highlights: • A planar ICP was used to grow a-Si:H films for c-Si surface passivation. • The direct- and remote-plasma was compared for high-quality c-Si surface passivation. • The remote ICP with controlled plasma species and ion bombardments is preferable for the surface passivation of c-Si. - Abstract: Being a key issue in the research and fabrication of silicon heterojunction (SHJ) solar cells, crystalline silicon (c-Si) surface passivation is theoretically and technologically intricate due to its complicate dependence on plasma characteristics, material properties, and plasma-material interactions. Here amorphous silicon (a-Si:H) grown by a planar inductively coupled plasma (ICP) reactor working under different antenna-substrate distances of d was used for the surface passivation of low-resistivity p-type c-Si. It is found that the microstructures (i.e., the crystallinity, Si-H bonding configuration etc.) and passivation function on c-Si of the deposited a-Si:H were profoundly influenced by the parameter of d, which primarily determines the types of growing precursors of SiH{sub n}/H contributing to the film growth and the interaction between the plasma and growing surface. c-Si surface passivation is analyzed in terms of the d-dependent a-Si:H properties and plasma characteristics. The controlling of radical types and ion bombardment on the growing surface through adjusting parameter d is emphasized.

  13. VizieR Online Data Catalog: KiDS-ESO-DR3 multi-band source catalog (de Jong+, 2017)

    Science.gov (United States)

    de Jong, J. T. A.; Verdoes Kleijn, G. A.; Erben, T.; Hildebrandt, H.; Kuijken, K.; Sikkema, G.; Brescia, M.; Bilicki, M.; Napolitano, N. R.; Amaro, V.; Begeman, K. G.; Boxhoorn, D. R.; Buddelmeijer, H.; Cavuoti, S.; Getman, F.; Grado, A.; Helmich, E.; Huang, Z.; Irisarri, N.; La Barbera, F.; Longo, G.; McFarland, J. P.; Nakajima, R.; Paolillo, M.; Puddu, E.; Radovich, M.; Rifatto, A.; Tortora, C; Valentijn, E. A.; Vellucci, C.; Vriend, W-J.; Amon, A.; Blake, C.; Choi, A.; Fenech, Conti I.; Herbonnet, R.; Heymans, C.; Hoekstra, H.; Klaes, D.; Merten, J.; Miller, L.; Schneider, P.; Viola, M.

    2017-04-01

    KiDS-ESO-DR3 contains a multi-band source catalogue encompassing all publicly released tiles, a total of 440 survey tiles including the coadded images, weight maps, masks and source lists of 292 survey tiles of KiDS-ESO-DR3, adding to the 148 tiles released previously (50 in KiDS-ESO-DR1 and 98 in KiDS-ESO-DR2). (1 data file).

  14. Estimating the excess lifetime risk of radiation induced secondary malignancy (SMN) in pediatric patients treated with craniospinal irradiation (CSI): Conventional radiation therapy versus helical intensity modulated radiation therapy.

    Science.gov (United States)

    Holmes, Jordan A; Chera, Bhishamjit S; Brenner, David J; Shuryak, Igor; Wilson, Adam K; Lehman-Davis, Misty; Fried, David V; Somasundaram, Vivek; Lian, Jun; Cullip, Tim; Marks, Lawrence B

    To quantify the risk of radiation-induced second malignancies (SMN) in pediatric patients receiving craniospinal irradiation (CSI) either with 3-dimensional conformal radiation therapy (Conv CSI) or tomotherapy helical intensity modulated radiation therapy (Tomo CSI). A novel predictive model that accounts for short- and long-term carcinogenesis was incorporated into our institutional treatment planning system to quantify the lifetime risk of SMN in incidentally irradiated organs. Five pediatric patients previously treated with CSI were studied. For each case, Conv CSI and Tomo CSI plans were computed. The excess absolute number of SMN was computed for each plan for each patient. For female patients, age was varied to assess its impact. Tomo CSI has a much higher risk than Conv CSI for breast cancer. Tomo has a slightly increased risk for the lung, and conventional has a slightly higher risk for the thyroid. Both techniques have intermediate risks to the pancreas and stomach, and lesser risks to the bladder and rectum. For the breast, the magnitude of the absolute risks varied with age: 14.2% versus 7.4% (Tomo vs Conv) age 5; 16.9% versus 7.6% age 10, and 18.6% versus 8.0% age 15. Tomo has a higher risk for inducing breast and lung second cancers, and when using Tomo-based intensity modulated radiation therapy, care should be taken to avoid incidental radiation to the breast. When planning CSI, one needs to balance these cancer risks against other normal tissue effects. Copyright © 2016. Published by Elsevier Inc.

  15. Radiomic features predict Ki-67 expression level and survival in lower grade gliomas.

    Science.gov (United States)

    Li, Yiming; Qian, Zenghui; Xu, Kaibin; Wang, Kai; Fan, Xing; Li, Shaowu; Liu, Xing; Wang, Yinyan; Jiang, Tao

    2017-11-01

    To investigate the radiomic features associated with Ki-67 expression in lower grade gliomas and assess the prognostic values of these features. Patients with lower grade gliomas (n = 117) were randomly assigned into the training (n = 78) and validation (n = 39) sets. A total of 431 radiological features were extracted from each patient. Differential radiological features between the low and high Ki-67 expression groups were screened by significance analysis of microarrays. Then, generalized linear analysis was performed to select features that could predict the Ki-67 expression level. Predictive efficiencies were further evaluated in the validation set. Cox regression analysis was performed to investigate the prognostic values of Ki-67 expression level and Ki-67-related radiological features. A group of nine radiological features were screened for prediction of Ki-67 expression status; these achieved accuracies of 83.3% and 88.6% (areas under the curves, 0.91 and 0.93) in the training and validation sets, respectively. Of these features, only spherical disproportion (SD) was found to be a prognostic factor. Patients in the high SD group exhibited worse outcomes in the whole cohort (overall survival, p level and SD were independent prognostic factors in the multivariate Cox regression analysis. This study identified a radiomic signature for prediction of Ki-67 expression level as well as a prognostic radiological feature in patients with lower grade gliomas.

  16. Proliferation marker pKi-67 occurs in different isoforms with various cellular effects.

    Science.gov (United States)

    Schmidt, Mirko H H; Broll, Rainer; Bruch, Hans-Peter; Finniss, Susan; Bögler, Oliver; Duchrow, Michael

    2004-04-15

    The Ki-67 antigen, pKi-67, is a commonly used proliferation marker in research and pathology. It has been recognized that the protein exists in two different splice variants that differ in one exon. In the current work, we present three new splice variants of human pKi-67 consisting of two naturally occurring isoforms and one atypical version. Additionally, data is presented indicating that alternative splicing of the pKi-67 N-terminus is common in tumor cell lines. Analyzing 93 tissues mainly consisting of brain tumor specimens, we found evidence that long and short isoform can be expressed independently of each other. Induction of mitosis in human peripheral blood mononuclear cells revealed that short pKi-67 appears earlier in the cell cycle than the long isoform and reaches its expression maximum when transcription of the latter sets in. Finally, transfection of mammalian culture cells with exon 7 (specific for the long pKi-67 isoform and not present in the short isoform) in a tetracycline regulated expression system decreased the rate of cell proliferation without affecting the cell cycle. In summary, we present evidence that the pKi-67 N-terminus is differentially spliced resulting in at least five different isoforms with different functions. Copyright 2004 Wiley-Liss, Inc.

  17. Expression and Significance of COX-2 and Ki-67 in Hepatolithiasis with Bile Duct Carcinoma.

    Science.gov (United States)

    Wang, Ping; He, Yu; Ma, Xiaodong; Sun, Beiwang; Huang, Binyuan; Zhu, Canhua; Liu, Yanmin

    2015-10-01

    As an induced enzyme, COX-2 expression is elevated under stimuli from inflammatory mediator or growth factor product. Ki-67, a cell cycle-related proliferative antigen, reflects the tissue proliferative activity. This study analyzed the expressional profile of cyclooxygenase-2 (COX-2) and Ki-67 in hepatolithiasis and bile duct carcinoma tissues, in an attempt to provide evidence for diagnosis and prognosis prediction of disease. A cohort of tissue samples from hepatolithiasis with bile duct carcinoma (N=47) patients were analyzed using immunohistochemical (IHC) staining method for the expression of COX-2 and Ki-67, in parallel with hepatolithiasis (N=44) and normal bile duct tissues (N=30). The relationship between expression pattern of COX-2 and Ki-67 and pathological conditions was also analyzed, in addition to the correlation with positive expression in hepatolithiasis samples. The positive expression rate of COX-2 and Ki-67 in bile duct carcinoma was 76.6% and 80.9%, respectively, and was significantly higher than those in the hepatolithiasis group, which was also higher than the control group. Expression of both COX-2 and Ki-67 is closely related to TNM staging, lymph node metastasis, and differentiation stage. They were also correlated with the mortality rate of patients. Both COX-2 and Ki-67 are abundantly expressed in hepatolithiasis and bile duct carcinoma tissues and may play an important role in the disease occurrence, progression, and metastasis.

  18. Proliferation marker pKi-67 affects the cell cycle in a self-regulated manner.

    Science.gov (United States)

    Schmidt, Mirko H H; Broll, Rainer; Bruch, Hans-Peter; Duchrow, Michael

    2002-01-01

    The proliferation marker pKi-67 is commonly used in research and pathology to detect proliferating cells. In a previous work, we found the protein to be associated with regulators of the cell cycle, controlling S-phase progression, as well as entry into and exit from mitosis. Here we investigate whether pKi-67 has a regulative effect on the cell cycle itself. For that purpose we cloned four fragments of pKi-67, together representing nearly the whole protein, and an N-terminal pKi-67 antisense oligonucleotide into a tetracycline inducible gene expression system. The sense fragments were C-terminally modified by addition of either a nuclear localization sequence (NLS) or a STOP codon to address the impact of their intracellular distribution. FACS based cell cycle analysis revealed that expression of nearly all pKi-67 domains and the antisense oligonucleotide led to a decreased amount of cells in S-phase and an increased number of cells in G(2)/M- and G(1)-phase. Subsequent analysis of the endogenous pKi-67 mRNA and protein levels revealed that the constructs with the most significant impact on the cell cycle were able to silence pKi-67 transcription as well. We conclude from the data that pKi-67 influences progression of S-phase and mitosis in a self-regulated manner and, therefore, effects the cell cycle checkpoints within both phases. Furthermore, we found pKi-67 mediates an anti-apoptotic effect on the cell and we verified that this marker, although it is a potential ribosomal catalyst, is not expressed in differentiated tissues with a high transcriptional activity. Copyright 2002 Wiley-Liss, Inc.

  19. VizieR Online Data Catalog: KiDS-ESO-DR3 multi-band source catalog (de Jong+, 2017)

    NARCIS (Netherlands)

    de Jong, J. T. A.; Verdoes Kleijn, G. A.; Erben, T.; Hildebrandt, H.; Kuijken, K.; Sikkema, G.; Brescia, M.; Bilicki, M.; Napolitano, N. R.; Amaro, V.; Begeman, K. G.; Boxhoorn, D. R.; Buddelmeijer, H.; Cavuoti, S.; Getman, F.; Grado, A.; Helmich, E.; Huang, Z.; Irisarri, N.; La Barbera, F.; Longo, G.; McFarland, J. P.; Nakajima, R.; Paolillo, M.; Puddu, E.; Radovich, M.; Rifatto, A.; Tortora, C; Valentijn, E. A.; Vellucci, C.; Vriend, W-J.; Amon, A.; Blake, C.; Choi, A.; Fenech Conti, I.; Herbonnet, R.; Heymans, C.; Hoekstra, H.; Klaes, D.; Merten, J.; Miller, L.; Schneider, P.; Viola, M.

    2017-01-01

    KiDS-ESO-DR3 contains a multi-band source catalogue encompassing all publicly released tiles, a total of 440 survey tiles including the coadded images, weight maps, masks and source lists of 292 survey tiles of KiDS-ESO-DR3, adding to the 148 tiles released previously (50 in KiDS-ESO-DR1 and 98 in

  20. Computerized image analysis of the Ki-67 proliferation index in mantle cell lymphoma

    DEFF Research Database (Denmark)

    Blaker, Yngvild N; Brodtkorb, Marianne; Maddison, John

    2015-01-01

    AIMS: Manual counting of the fraction of Ki-67-positive cells (the Ki-67 index) in 1000 tumour cells is considered the 'gold standard' to predict prognosis in mantle cell lymphoma (MCL). This time-consuming method is replaced by the faster, but less accurate, semiquantitative estimation in routine...... obtained by semiquantitative estimation was not associated significantly with survival (P = 0.093). The results were validated in a second patient cohort with similar results. CONCLUSION: Computerized image analysis of the Ki-67 index in MCL is an attractive alternative to semiquantitative estimation...

  1. Lysozyme pattern formation in evaporating droplets

    Science.gov (United States)

    Gorr, Heather Meloy

    Liquid droplets containing suspended particles deposited on a solid, flat surface generally form ring-like structures due to the redistribution of solute during evaporation (the "coffee ring effect"). The forms of the deposited patterns depend on complex interactions between solute(s), solvent, and substrate in a rapidly changing, far from equilibrium system. Solute self-organization during evaporation of colloidal sessile droplets has attracted the attention of researchers over the past few decades due to a variety of technological applications. Recently, pattern formation during evaporation of various biofluids has been studied due to potential applications in medical screening and diagnosis. Due to the complexity of 'real' biological fluids and other multicomponent systems, a comprehensive understanding of pattern formation during droplet evaporation of these fluids is lacking. In this PhD dissertation, the morphology of the patterns remaining after evaporation of droplets of a simplified model biological fluid (aqueous lysozyme solutions + NaCl) are examined by atomic force microscopy (AFM) and optical microscopy. Lysozyme is a globular protein found in high concentration, for example, in human tears and saliva. The drop diameters, D, studied range from the micro- to the macro- scale (1 microm -- 2 mm). In this work, the effect of evaporation conditions, solution chemistry, and heat transfer within the droplet on pattern formation is examined. In micro-scale deposits of aqueous lysozyme solutions (1 microm < D < 50 microm), the protein motion and the resulting dried residue morphology are highly influenced by the decreased evaporation time of the drop. The effect of electrolytes on pattern formation is also investigated by adding varying concentrations NaCl to the lysozyme solutions. Finally, a novel pattern recognition program is described and implemented which classifies deposit images by their solution chemistries. The results presented in this Ph

  2. Evaporation-triggered microdroplet nucleation and the four life phases of an evaporating Ouzo drop

    NARCIS (Netherlands)

    Tan, Huanshu; Tan, Huanshu; Diddens, Christian; Lv, Pengyu; Kuerten, Johannes G.M.; Zhang, Xuehua; Zhang, Xuehua; Lohse, Detlef

    2016-01-01

    Evaporating liquid droplets are omnipresent in nature and technology, such as in inkjet printing, coating, deposition of materials, medical diagnostics, agriculture, the food industry, cosmetics, or spills of liquids. Whereas the evaporation of pure liquids, liquids with dispersed particles, or even

  3. KiSS1 and its G-protein-coupled receptor GPR54 in cancer development and metastasis.

    Science.gov (United States)

    Cho, Sung-Gook; Li, Dali; Tan, Kunrong; Siwko, Stefan K; Liu, Mingyao

    2012-12-01

    KiSS1 and its cognate G-protein-coupled receptor, GPR54, have diverse functions. While KiSS1 and GPR54 have been intensively studied in physiology, their role in cancer is still unclear. In cancer, KiSS1 and GPR54 have been known to suppress metastasis by inhibiting cancer cell motility. However, recent studies suggest that KiSS1 and GPR54 have varied roles even in cancer development and metastasis. Here, we examine recent advances in understanding the roles of KiSS1 and GPR54 in cancer development and metastasis.

  4. Evaporation Heat Transfer of Ammonia/Water Mixtures for Plate Type Evaporator

    Science.gov (United States)

    Kushibe, Mitsuteru; Ikegami, Yasuyuki; Monde, Masanori

    The performance test of plate type evaporators was carried out. Ammonia/Water mixtures were utilized as working fluid and warm water was utilized as heat source. Five kinds of ammonia mass fraction are tested. The overall heat transfer coefficient of ammonia/water mixtures was lower than the pure ammonia in the same experimental condition. In the convection dominant region, the mean evaporation heat transfer of ammonia/water mixtures was almost the same as ammonia by considering thermophysical properties. In the region where nucleate boiling contributes to the heat transfer, the mean evaporation heat transfer coefficient was influenced of mass fraction. An empirical correlation was proposed in order to predict the mean evaporation heat transfer coefficient of ammonia/water mixtures for plate type evaporators.

  5. The kisspeptin (KiSS-1)/GPR54 system in cancer biology.

    Science.gov (United States)

    Makri, Angeliki; Pissimissis, Nikolaos; Lembessis, Peter; Polychronakos, Constantine; Koutsilieris, Michael

    2008-12-01

    Kisspeptin (KiSS-1) gene, initially described as a melanoma metastasis suppressor gene, encodes a number of peptides (kp-54, kp-14, kp-13, kp-10), which are endogenous ligands to a G protein-coupled receptor, referred as hOT7T175 or AXOR12 or GPR54. So far intensive investigation has provided substantiate evidence supporting the role of KiSS-1/GPR54 system in cancer biology as well as in the regulation of the reproductive function and trophoblast invasion. The precise mechanism by which KiSS-1/GPR54 system is affecting cancer cell growth and metastasis includes complex endocrine, paracrine and autocrine actions. Nevertheless, the detail mechanism of such actions is still under intensive investigation. Herein we review the evidence which support the role of KiSS-1/GPR54 system in cancer biology.

  6. Proliferating cell nuclear antigen and Ki-67 immunohistochemistry of oligodendrogliomas with special reference to prognosis

    DEFF Research Database (Denmark)

    HEEGAARD, S.; Sommer, Helle Mølgaard; BROHOLM, H.

    1995-01-01

    Background. The biologic behavior of oligodendrogliomas is somewhat unpredictable. A supplementary prognostic factor is, therefore, desirable. Methods. Thirty-two pure supratentorial oligodendrogliomas were investigated using proliferating cell nuclear antigen (PCNA) and Ki-67 immunohistochemical...

  7. 500 kodu on pandud sundmüüki / Agnes Ojala

    Index Scriptorium Estoniae

    Ojala, Agnes

    2009-01-01

    Swedbank ja SEB on pannud sundmüüki kokku ligi 500 eluaset. Swedbank Eesti juhi Priit Perensi, Sampo Panga personaal- ja jaepanganduse direktori Tõnu Vanajuure, kohtutäitur Mati Kadaku kommentaare

  8. Expression of Oestrogen and progesterone receptors, Ki-67,p53 and ...

    African Journals Online (AJOL)

    Expression of Oestrogen and progesterone receptors, Ki-67,p53 and bcl-2 proteins, cathepsin D, urokinase plasminogen activator and urokinase plasminogen activator-receptors in carcinomas of the female breast in an African population.

  9. Ki-67 Membranous Staining: Biologically Relevant or an Artifact of Multiplexed Immunofluorescent Staining.

    Science.gov (United States)

    Wang, Dan; Pang, Zhengyu; Clarke, Gina M; Nofech-Mozes, Sharon; Liu, Kela; Cheung, Alison M Y; Filkins, Robert J; Yaffe, Martin J

    2016-07-01

    In the process of developing a multiplex of 8 common breast cancer biomarkers (Her2/neu, estrogen receptor, progesterone receptor, Ki-67, aldehyde dehydrogenase-1, NaK-ATPase, cytokeratin 8/18, and myosin smooth muscle) on a single formalin-fixed paraffin-embedded slide using a sequential staining, imaging, and dye bleaching technology developed by General Electric Company, membranous Ki-67 staining was observed and colocalized with Her2/neu staining. Using immunohistochemistry as gold standards, we discovered that membranous Ki-67 was an artifact caused by the binding of cyanine 5-conjugated rabbit polyclonal Ki-67 antibody to a secondary cyanine 3-conjugated donkey anti-rabbit antibody which was previously applied and bound to rabbit Her2/neu antibody in our multiplexing experiment. After blocking with rabbit serum, a successful protocol for 8 biomarker multiplexing without cross-reactivity of antibodies from the same species was developed.

  10. Beebitoidu müüki hakkab korraldama range koodeks / Eha Laanepere

    Index Scriptorium Estoniae

    Laanepere, Eha, 1963-

    1995-01-01

    Rinnapiima asendajate reklaami ja müüki reguleerivast rahvusvahelisest koodeksist International Baby Food Action Network (IBFAN), mis on vastu võetud 1982. aastal, selle seadustiku vajalikkusest Eestis

  11. Use of the Central Sensitization Inventory (CSI) as a treatment outcome measure for patients with chronic spinal pain disorder in a functional restoration program.

    Science.gov (United States)

    Neblett, Randy; Hartzell, Meredith M; Williams, Mark; Bevers, Kelley R; Mayer, Tom G; Gatchel, Robert J

    2017-06-12

    The Central Sensitization Inventory (CSI) is a valid and reliable patient-reported instrument designed to identify patients whose presenting symptoms may be related to central sensitization (CS). Part A of the CSI measures a full array of 25 somatic and emotional symptoms associated with CS, and Part B asks if patients have previously been diagnosed with one or more specific central sensitivity syndromes (CSSs) and related disorders. The CSI has previously been validated in a group of patients with chronic pain who were screened by a trained psychiatrist for specific CSS diagnoses. It is currently unknown if the CSI can be a useful treatment-outcome assessment tool for patients with chronic spinal pain disorder (CSPD) who are not screened for comorbid CSSs. It is known, however, that previous studies have identified CS-related symptoms, and comorbid CSSs, in subsets of patients with CSPDs. Studies have also shown that CS-related symptoms can be influenced by cognitive and psychosocial factors, including abuse history in both childhood and adulthood, sleep disturbance, catastrophic and fear-avoidant cognitions, and symptoms of depression and anxiety. This study aimed to evaluate CSI scores, and their associations with other clinically relevant psychosocial variables, in a cohort of patients with CSPD who entered and completed a functional restoration program. A retrospective study of prospectively collected data from a cohort study of patients with CSPD, who completed the CSI at admission to, and discharge from, an interdisciplinary function restoration program (FRP) was carried out. A cohort of 763 patients with CSPD comprised the study sample. Clinical interviews evaluated mood disorders and abuse history. A series of self-reported measures evaluated comorbid psychosocial symptoms, including pain intensity, pain-related anxiety, depressive symptoms, somatization symptoms, perceived disability, and sleep disturbance, at FRP admission and discharge. Patients were

  12. Ki-67 overexpression in WHO grade II gliomas is associated with poor postoperative seizure control.

    Science.gov (United States)

    Yuan, Yang; Xiang, Wang; Yanhui, Liu; Ruofei, Liang; Shuang, Liu; Yingjun, Fan; Qiao, Zhou; Yanwu, Yang; Qing, Mao

    2013-12-01

    Seizures are the most common initial symptom in patients with low-grade gliomas, and approximately 30% of these patients still suffer from epilepsy after gross-total resection of the tumour. We examined the relationship between the overexpression of ki-67 in WHO grade II gliomas and seizure control. A series of 93 histologically confirmed WHO grade II glioma tissues were analysed through immunohistochemical staining for ki-67 expression. Follow-up visits regarding seizure control were scheduled at 12 months. The Engel classification was used to categorise patients' seizure status. Of the 93 patients analysed, 65 (66.3%) patients initially presented with seizures. A total of 36 patients were diagnosed with WHO grade II oligodendrogliomas, 29 patients had oligoastrocytomas and 28 patients had astrocytomas. Ki-67 was over-expressed in 15 patients. One year after surgery poor seizure control was observed in 11 of these patients. In contrast, low ki-67 expression (seizure control was observed in 36 patients (difference between ki-67 over- and low expression groups P = 0.002). Logistic regression analysis revealed that patients with gross-total resection achieved better seizure control while ki-67 overexpression and age below 38 years were poor seizure control factors explained of the variance of seizure outcome (OR: 0.382, 4.354 and 1.822, respectively). In WHO grade II gliomas, Ki-67 is a molecular marker which predicts poor seizure control of glioma patients after the resection of the tumour. Gross-total resection, ki-67 overexpression and age below 38 years significantly affect seizure prognosis. Copyright © 2013 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.

  13. Expression and significance of VEGF, CD34, Ki-67 and p21 in pterygium

    Directory of Open Access Journals (Sweden)

    Li-Bo Wang

    2014-07-01

    Full Text Available AIM: To investigate the expression of VEGF, CD34, Ki-67 and p21 in pterygium as well as the correlation between their expression and clinical pathological characteristics; explore its pathogenesis. METHODS: Immunohistochemical S-P staining method was adopted in detecting the expression of VEGF, CD34, Ki-67 and p21 in 62 cases of pterygia and 20 cases of normal conjunctival tissues. Relationship between these markers and clinical pathological characteristics was analyzed. RESULTS:(1The positive expression of VEGF, CD34, Ki-67 and p21 in 62 cases of pterygia was 74.2%(46/62, 77.4%(48/62, 66.1%(41/62and 40.3%(25/62respectively. The differences were statistically significant compared with normal conjunctival tissues(PPP>0.05; the expression of Ki-67 was correlated with clinical stages(PP>0.05; the expression of p21 was correlated with clinical stages and pterygium characters(PP>0.05.(3Spearman correlation showed that there was a positive correlation between VEGF and Ki-67(r=0.279, Pr=0.299, Pr=-0.267, PP>0.05.CONCLUSION:(1Overexpression of VEGF, Ki-67, CD34 and low expression of p21 suggest that these markers are concerned with the development and progression of pterygium.(2Expression of VEGF and CD34 increases along with the increase of clinical types and stages, expression of Ki-67 increases along with the increase of clinical stages, and expression of p21 decreases along with the improvement of clinical types or stages; they suggest that these markers may play important roles in the development and recurrence of pterygium.(3There is positive correlation between VEGF and Ki-67, VEGF and CD34 as well as negative correlation between VEGF and p21. They suggest that there may be synergistic action between two factors during the development and progression of pterygium.

  14. Transformation in Dang-ki Healing: The Embodied Self and Perceived Legitimacy.

    Science.gov (United States)

    Lee, Boon-Ooi

    2016-09-01

    Since spirit possession in mediumship and shamanism resembles psychotic symptoms, early researchers perceived spirit mediums and shamans as psychiatric patients whose psychopathology was culturally sanctioned. However, other researchers have not only challenged this assumption, but also proposed that spirit possession has transformative benefits. The idiom of spirit possession provides cultural meanings for spirit mediums and shamans to express and transform their personal experiences. The present case study focuses on dang-ki healing, a form of Chinese mediumship practiced in Singapore, in which a deity possesses a human (i.e., dang-ki) to offer aid to supplicants. This study seeks to explore whether involvement in dang-ki healing is transformative; and if so, how the dang-ki's transformation is related to his self and the perceived legitimacy of his mediumship. At a shrine, I interviewed 20 participants, including a male dang-ki, 10 temple assistants, and nine clients. The results obtained were supportive of the therapeutic nature of spirit possession. First, there is a relationship between his self-transformation and the perceived legitimacy of his mediumship. As his clients and community have recognized his spirit possession as genuine, and the healing power of his possessing god, he is able to make use of mediumship as a means for spiritual development. Second, he has developed his spirituality by internalizing his god's positive traits (e.g., compassion). Deities worshipped in dang-ki healing can be conceptualized as ideal selves who represent a wide range of positive traits and moral values of Chinese culture. Thus, the possession of a deity is the embodiment of an ideal self. Finally, the dang-ki's transformation may run parallel to his god's transformation. In Chinese religions, gods have to constantly develop their spirituality even though they are already gods. An understanding of the god's spiritual development further sheds light on the dang-ki's self-transformation.

  15. Prognostic value of Ki-67 expression in conversion therapy for colorectal liver-limited metastases

    OpenAIRE

    Hayashi, Hiromitsu; Beppu, Toru; Sakamoto, Yasuo; Miyamoto, Yuji; Yokoyama, Naomi; Higashi, Takaaki; Nitta, Hidetoshi; Hashimoto, Daisuke; Chikamoto, Akira; Baba, Hideo

    2015-01-01

    Introduction: The objective of this study was to examine the prognostic value of Ki-67 expression in conversion therapy for colorectal liver-confined metastases. Methods: We enrolled a total of 96 patients including 54 patients who received oxaliplatin- or irinotecan-based chemotherapy and curative hepatectomy for initially unresectable metastases (conversion group) and 42 patients with initially resectable liver metastases (straight hepatectomy group). Ki-67 expression was examined in 96 res...

  16. Chromatin preferences of the perichromosomal layer constituent pKi-67.

    Science.gov (United States)

    Traut, Walther; Endl, Elmar; Garagna, Silvia; Scholzen, Thomas; Schwinger, Eberhard; Gerdes, Johannes; Winking, Heinz

    2002-01-01

    The proliferation-associated nuclear protein pKi-67 relocates from the nucleolus to the chromosome surface during the G2/M transition of the cell cycle and contributes to the formation of the 'perichromosomal layer'. We investigated the in-vivo binding preferences of pKi-67 for various chromatin blocks of the mitotic chromosomes from the human and two mouse species, Mus musculus and M. caroli. All chromosomes were decorated with pKi-67 but displayed a gap of pKi-67 decoration in the centromere and NOR regions. pKi-67 distribution in a rearranged mouse chromosome showed that the formation of the centromeric gap was controlled by the specific chromatin in that region. While most chromatin served as a substrate for direct or indirect binding of pKi-67, we identified three types of chromatin that bound less or no pKi-67. These were: (1) the centromeric heterochromatin defined by the alpha satellite DNA in the human, by the mouse minor satellite in M. musculus and the 60- and 79-bp satellites in M. caroli; (2) the pericentromeric heterochromatin in M. musculus defined by the mouse major satellite, and (3) NORs in the human and in M. musculus defined by rDNA repeats. In contrast, the conspicuous blocks of pericentromeric heterochromatin in human chromosomes 1, 9 and 16 containing the 5-bp satellite showed intense pKi-67 decoration. The centromeric gap may have a biological significance for the proper attachment of the chromosomes to the mitotic spindle. In this context, our results suggest a new role for centromeric heterochromatin: the control of the centromeric gap in the perichromosomal layer.

  17. The Values of Ki Hadjar Dewantara's Critical Education: Fundamental Concept of Accounting Education Objective

    OpenAIRE

    Bakhtiar, Yohan; Triyuwono, Iwan; Irianto, Gugus

    2015-01-01

    This article analyzesthe currentofaccounting educationreality and founds a relevance values that ​​brought by modern accounting with Ki Hadjar Dewantara's thinking. Additionally, this article explores the values ​​of Ki Hadjar Dewantara's critical education as aformulation for basic concept of accounting education objective. Islamic spiritual value, moral value​​and freedomvalue which become the findings in this article are still a conceptual framework that requires ongoing study to obtain in...

  18. Measurements of the radiolytic oxidation of aqueous CsI using a sparging apparatus

    Energy Technology Data Exchange (ETDEWEB)

    Ashmore, C.B.; Brown, D.; Sims, H.E. [AEA Technology, Harwell (United Kingdom); Gwyther, J.R. [NE plc Berkeley Technology Centre, Berkeley (United Kingdom)

    1996-12-01

    Radiolytic oxidation is considered to be the main mechanism for the formation of I{sub 2} from aqueous CsI in containment of a water cooled reactor after a LOCA. Despite the amount of study over the last 60 years on the radiation chemistry of iodine there has been no consistent set of experiments spanning a wide enough range of conditions to verify models with confidence. This paper describes results from a set of experiments carried out in order to remedy this deficiency. In this work the rate of evolution of I{sub 2} from sparged irradiated CsI solution labeled with {sup 131}I was measured on-line over a range of conditions. This work involved the measurement of the effects of pH, temperature, O{sub 2} concentration, I{sup -} concentration, phosphate concentration, dose-rate and impurities on the rate of evolution of I{sub 2}. The range of conditions was chosen in order to span as closely as possible conditions expected in a LOCA but also to help to elucidate some of the mechanisms especially at high pH. pH was found to be a very important factor influencing iodine volatility, over the temperature range studied the extent of oxidation reduced with temperature but this was compensated for by the decrease in partition coefficient. Oxygen concentration was more important in solutions not containing phosphate. The fractional oxidation was not particularly dependent on iodide concentration but G{sub I2} was very dependent on [I{sup -}]. There was no effect of added impurities, Fe, Mn, Mo or organics although in separate work silver was found to have a very important effect. During attempts to interpret the data it was found that it was necessary to include the iodine atom as a volatile species with a partition coefficient of 1.9 taken from thermodynamic data. The modelling work is described in a separate paper. (author) 15 figs., 1 tab., 19 refs.

  19. An evaporation based digital microflow meter

    Science.gov (United States)

    Nie, C.; Frijns, A. J. H.; Mandamparambil, R.; Zevenbergen, M. A. G.; den Toonder, J. M. J.

    2015-11-01

    In this work, we present a digital microflow meter operating in the range 30-250 nl min-1 for water. The principle is based on determining the evaporation rate of the liquid via reading the number of wetted pore array structures in a microfluidic system, through which continuous evaporation takes place. A proof-of-principle device of the digital flow meter was designed, fabricated, and tested. The device was built on foil-based technology. In the proof-of-principle experiments, good agreement was found between set flow rates and the evaporation rates estimated from reading the number of wetted pore structures. The measurement range of the digital flow meter can be tuned and extended in a straightforward manner by changing the pore structure of the device.

  20. Adaptación del Inventario de Estrategias de Afrontamiento (CSI a la población penitenciaria de Mexico

    Directory of Open Access Journals (Sweden)

    Francisco Javier Rodríguez-Díaz

    2014-01-01

    Full Text Available El objetivo del estudio es adaptar el CSI - Inventario de Estrategias de Afrontamiento - al contexto penitenciario. La muestra - 261 penados, 97% varones (n=253 - del Sistema Postpenitenciario y Atención a Liberados (DSPAL del Estado Jalisco, México. Los instrumentos utilizados: Ficha Penitenciaria de Historia de Vida y el Inventario CSI. Los resultados refieren una estructura de primer orden casi idéntica a la obtenida para la población general, con niveles de consistencia interna satisfactorios, al mismo tiempo que la interpretación de segundo orden no confirma la estructura de segundo y tercer orden. Se discuten las implicaciones de los resultados para intervención penitenciaria.

  1. Impact of I/Q imbalance on the performance of two-way CSI-assisted AF relaying

    KAUST Repository

    Qi, Jian

    2013-04-01

    In this paper, we investigate half-duplex two-way dual-hop channel state information (CSI)-assisted amplify-and-forward (AF) relaying in the presence of in-phase and quadrature-phase (I/Q) imbalance. A compensation approach for the I/Q imbalance is proposed, which employs the received signals together with their conjugations to detect the desired signal. We also derive the average symbol error probability of the considered half-duplex two-way dual-hop CSI-assisted AF relaying networks with and without compensation for I/Q imbalance in Rayleigh fading channels. Numerical results are provided and show that the proposed compensation method mitigates the impact of I/Q imbalance to a certain extent. © 2013 IEEE.

  2. Community identity politics of Brijo Lor society, Klaten in Ki Ageng Glego myth through Reog performance

    Directory of Open Access Journals (Sweden)

    Sutiyono Sutiyono

    2017-12-01

    Full Text Available This research is aimed to describe community identity politics of Brijo Lor society, Klaten in Ki Ageng Glego myth through Reog performance. The research questions are how is the community identity politics in Brijo Lor society, and what is the relationship between the identity politics with Ki Ageng Glego myth through Reog performance? The research approach used is qualitative. Data collecting technique was obtained by these ways: observation, documentation, literature, and interview. Data analysis was conducted by: data collection, data reduction, data diagnose, and conclusion. To ensure the validity of the data, the researcher conducted triangulation. The result of this research proposed that community identity politics in Brijo Lor society in preserveing Reog is a strategy to maintain traditional art for many other traditional arts are extinct. Reog performance conducted regularly is a mediationof the society who ngalap berkah (beg for blessing to Ki Ageng Glego spirit. When Reog is performed, Ki Ageng Glego spirit descends upon the world. Many people come to watch Reog because they want to get blessing for the descend of Ki Ageng Glego spirit. Ki Ageng Glego myth became an identity political way of Brijo Lor society through Reog performance.

  3. Cyclooxygenase-2 and Ki67 Expression in Oral Leukoplakia: a Clinicopathological Study

    Directory of Open Access Journals (Sweden)

    Alper Sinanoglu

    2015-06-01

    Full Text Available Objectives: Oral leukoplakia is a precancerous lesion of the oral mucosa. The upregulation of Ki67 and cyclooxygenase-2 has been reported in both dysplastic and non-dysplastic tissues. The aim of this clinicopathological study was to investigate the prognostic value of Ki67 and cyclooxygenase-2 expression for oral leukoplakia. Material and Methods: A total of 50 samples were investigated and the study group consisted of 30 oral leukoplakia samples. Samples of 10 intact oral mucosa and 10 squamous cell carcinoma were included as negative and positive control groups, respectively. Epithelial dysplasia was defined as oral intraepithelial neoplasia (OIN and classified into subgroups 1 - 3. Tissue samples were assessed immunohistochemically for Ki67 and cyclooxygenase-2 expression. Clinicopathological correlations of oral leukoplakia patients were also investigated. Results: All OIN 3 patients were non-smokers (P < 0.05, and homogeneous oral leukoplakia lesions also presented OIN. Both cyclooxygenase-2 and Ki67 expression increased with the severity of lesions, which defined different subgroups (P < 0.05, except there was no significant difference between the hyperkeratosis and OIN groups for Ki67 expression. Conclusions: Cyclooxygenase-2 and Ki67 expression may have a prognostic value for the malignant transformation of oral leukoplakia.

  4. Immunohistochemical detection of laminin-1 and Ki-67 in radicular cysts and keratocystic odontogenic tumors

    Directory of Open Access Journals (Sweden)

    El-Kholy Moataz

    2011-03-01

    Full Text Available Abstract Background Odontogenic cysts are those which arise from the epithelium associated with the development of teeth. Some odontogenic cysts were found to have special biological features that make them distinct from other lesions. This study was conducted to detect the immunoepxression of laminin-1 and Ki-67 in both radicular cysts (RCs and keratocystic odontogenic tumors (KCOTs and to examine the possible predictive value of these markers. Methods Thirteen cases of RCs and twelve cases of KCOTs were included in this study. Antibodies against laminin-1 and Ki-67 were used as primary antibodies. Results ten cases out of thirteen cases of RCs were immunopositive to laminin-1. The immunonegative cases of RCs showed high degree of inflammation inside the connective tissue wall. One case out of twelve cases of KCOTs was immunopositive to laminin-1 and the rest were immunonegative. Seven cases out of thirteen cases of RCs showed immunopositivity for Ki-67 with increased numbers of immunopositive cells when the inflammation was severe in the connective tissue wall. All KCOTS were immunopositive to Ki-67. Conclusions The benign nature of radicular cysts and the aggressive behavior of keratocystic odontogenic tumors could be explained by the expression of laminin and Ki-67. Laminin-1 and Ki-67 could be valuable markers for the prediction of the biologic behavior of cystic lesions.

  5. Teacher factors contributing to dosage of the KiVa anti-bullying program.

    Science.gov (United States)

    Swift, Lauren E; Hubbard, Julie A; Bookhout, Megan K; Grassetti, Stevie N; Smith, Marissa A; Morrow, Michael T

    2017-12-01

    The KiVa Anti-Bullying Program (KiVa) seeks to meet the growing need for anti-bullying programming through a school-based, teacher-led intervention for elementary school children. The goals of this study were to examine how intervention dosage impacts outcomes of KiVa and how teacher factors influence dosage. Participants included 74 teachers and 1409 4th- and 5th-grade students in nine elementary schools. Teachers and students completed data collection at the beginning and end of the school year, including measures of bullying and victimization, correlates of victimization (depression, anxiety, peer rejection, withdrawal, and school avoidance), intervention cognitions/emotions (anti-bullying attitudes, and empathy toward victims), bystander behaviors, and teacher factors thought to relate to dosage (self-efficacy for teaching, professional burnout, perceived principal support, expected effectiveness of KiVa, perceived feasibility of KiVa). The dosage of KiVa delivered to classrooms was measured throughout the school year. Results highlight dosage as an important predictor of change in bullying, victimization, correlates of victimization, bystander behavior, and intervention cognitions/emotions. Of the teacher factors, professional burnout uniquely predicted intervention dosage. A comprehensive structural equation model linking professional burnout to dosage and then to child-level outcomes demonstrated good fit. Implications for intervention design and implementation are discussed. Copyright © 2017 Society for the Study of School Psychology. Published by Elsevier Ltd. All rights reserved.

  6. CSI 3.0: a web server for identifying secondary and super-secondary structure in proteins using NMR chemical shifts.

    Science.gov (United States)

    Hafsa, Noor E; Arndt, David; Wishart, David S

    2015-07-01

    The Chemical Shift Index or CSI 3.0 (http://csi3.wishartlab.com) is a web server designed to accurately identify the location of secondary and super-secondary structures in protein chains using only nuclear magnetic resonance (NMR) backbone chemical shifts and their corresponding protein sequence data. Unlike earlier versions of CSI, which only identified three types of secondary structure (helix, β-strand and coil), CSI 3.0 now identifies total of 11 types of secondary and super-secondary structures, including helices, β-strands, coil regions, five common β-turns (type I, II, I', II' and VIII), β hairpins as well as interior and edge β-strands. CSI 3.0 accepts experimental NMR chemical shift data in multiple formats (NMR Star 2.1, NMR Star 3.1 and SHIFTY) and generates colorful CSI plots (bar graphs) and secondary/super-secondary structure assignments. The output can be readily used as constraints for structure determination and refinement or the images may be used for presentations and publications. CSI 3.0 uses a pipeline of several well-tested, previously published programs to identify the secondary and super-secondary structures in protein chains. Comparisons with secondary and super-secondary structure assignments made via standard coordinate analysis programs such as DSSP, STRIDE and VADAR on high-resolution protein structures solved by X-ray and NMR show >90% agreement between those made with CSI 3.0. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

  7. Logistički informacioni sistem / Logistics information system

    Directory of Open Access Journals (Sweden)

    Marko D. Andrejić

    2010-01-01

    Full Text Available Logistički automatizovani informacioni sistem treba razvijati kao deo jedinstvenog automatizovanog informacionog sistema (JAIS-a. Da bi se logistički automatizovani informacioni sistem uspešno razvijao i primenjivao u operativnoj praksi, neophodno je slediti globalni koncept razvoja JAIS-a i u razvoju više primenjivati timski rad profesionalnog informatičara i poznavaoca realnog logističkog sistema. Bitan uslov za razvoj kvalitetnog logističkog informacionog sistema jeste definisanje informacionih potreba o pojedinim objektima koje tretira logistički informacioni sistem. Zadatak logističkog automatizovanog informacionog sistema jeste da obezbedi: stalni uvid u stanje logističkog sistema; ukazivanje na potrebne i moguće mere poboljšanja; bolje planiranje i upravljanje radom realnog sistema; informisanje ljudstva o stanju realnog sistema i ukazivanje na pravce daljeg razvoja informacionih sistema. Logistički informacioni sistem treba razvijati vodeći računa i o kompatibilnosti sa budućim saveznicima i partnerima. / A logistics automated information system should be developed as a part of a unified automated information system (JAIS. In order to develop a logistics automated information system and to apply it successfully in operational use, it is necessary to follow the JAIS global development concept and rely more on teamwork of IT experts and specialists in real logistics systems. An important condition for the development of a high-quality logistics information system is to define information needs for particular objects treated by a logistics information system. The task of such a system is to provide: permanent insight into the logistics system, pointing to the necessary and possible measures for improvement, better real system planning and management activities, personnel information about the state of the real system, pointing to the directions of further system development. A logistics information system should be developed

  8. Black hole evaporation in conformal gravity

    Science.gov (United States)

    Bambi, Cosimo; Modesto, Leonardo; Porey, Shiladitya; Rachwał, Lesław

    2017-09-01

    We study the formation and the evaporation of a spherically symmetric black hole in conformal gravity. From the collapse of a spherically symmetric thin shell of radiation, we find a singularity-free non-rotating black hole. This black hole has the same Hawking temperature as a Schwarzschild black hole with the same mass, and it completely evaporates either in a finite or in an infinite time, depending on the ensemble. We consider the analysis both in the canonical and in the micro-canonical statistical ensembles. Last, we discuss the corresponding Penrose diagram of this physical process.

  9. CSI efekt a jeho vliv na vnímání forenzní biologie

    OpenAIRE

    Míková, Zuzana

    2016-01-01

    1 Abstract This bachelor thesis tries to give an outline on how the TV projects into our everyday life. There are many crime TV series that we can watch. These programmes unfortunately give a distorted view of the forensic and investigative work performed in crime laboratories, as they show a great number of inaccurate or altogether false information. This thesis shows some cases of the 'CSI effect', which emerged after crime series got increasingly popular both in the Czech Republic and abro...

  10. Comparative study of two different evaporative systems: an indirect evaporative cooler and a semi-indirect ceramic evaporative cooler

    Energy Technology Data Exchange (ETDEWEB)

    Rey Martinez, F.J.; Velasco Gomez, E.; Herrero Martin, R.; Martinez Gutierrez, J.; Varela Diez, F. [University of Valladolid (Spain). Thermal Engineering Group

    2004-07-01

    In the current work, two different types of evaporative systems are shown. A returning air recovery system is used. The indirect systems have two independent airflows, the primary airstream is used to refrigerate and the secondary flow is in direct contact with water in order to improve heat and mass transfer. The first equipment (the indirect evaporative refrigerator) works like a flat interchanger made of aluminium and there is only heat transfer in the primary airflow. The second equipment (the semi-indirect evaporative refrigerator) is made of solid porous ceramic pipes, which separate the two airstreams, thus allowing that, in the primary airflow (apart from the heat transfer), there is also a mass transfer. It should also be mentioned that this system is free of legionella, because the pipes perform the role of a filter material, making it impossible for the bacterium to enter premises. This system has been named a semi-indirect evaporative system due to the permeability of the porous pipes, which allow a higher or lower water diffusion and therefore a mass transfer depending on the specific humidity of the primary airstream. (author)

  11. Characterization of 3×3×10 cm3 CsI Crystals for Nuclear Physics Experiments

    Science.gov (United States)

    Sweany, Sean; Lynch, William; Tsang, Betty; Chajecki, Zbigniew; Brown, Kyle; Morfouace, Pierre; Kuan, Zhu; Crosby, Jacob; Anderson, Corinne; Kodali, Suhas

    2017-09-01

    The symmetry energy portion of the nuclear equation of state is currently poorly constrained in asymmetric nuclear matter. The momentum dependence of the symmetry energy potential causes a reduction in the nucleon masses causing a splitting between the neutron and proton effective masses. From transport simulations, n/p spectral ratios are shown to be a good observable for studying this effective mass splitting. Arrays of silicon strip detectors backed by scintillator crystals are an effective way of detecting and identifying charged particles over a large range of angles. Recently the HiRA group at the NSCL has finished updating of the HiRA array with 10 cm CsI crystals, HiRA10. The longer CsI crystals allow for higher energy particles to be measured. The doping gradient of thallium along with side and surface treatment of CsI can cause nonuniformity in light output of the crystals, therefore the crystals must characterized before use. For characterization, the crystals were scanned using a collimated Am241 source in a grid pattern of 64 points per crystal. The design of HiRA10 as well as the results of the tests for crystal uniformity will be presented in this talk. This material is based upon work supported by the National Science Foundation under Grant No. PHY 1565546.

  12. Law and Justice on TV. The Wire vs. CSI and Ally McBeal

    Directory of Open Access Journals (Sweden)

    Gianluigi Rossini

    2012-04-01

    Full Text Available The aim of this paper is to analyse the ways in which law is represented in the celebrated TV series The Wire, broadcasted in United States between 2002 and 2008. The analysis focuses particularly on the thematization of the relationship between the concept of law and that of justice, that is between 'positive law' and 'natural law'. This theme is pursued in the context of American television series of great success such as CSI: Crime Scene Investigation (CBS, 2000- and Ally McBeal (Fox, 1997-2002 . The comparison highlights the way in which in The Wire the terms of the problem are completely eroded through the representation of a sort of 'disappearance of justice'. In this series the natural law becomes insignificant both because it is no more the point of reference of the actions activated by the institutions, and because an informed, in-depth and not prejudicial gaze on the social reality of the contemporary metropolis brings into question the very idea of a justice absolute and distanced from the contingent circumstances.

  13. Delay analysis of a point-to-multipoint spectrum sharing network with CSI based power allocation

    KAUST Repository

    Khan, Fahd Ahmed

    2012-10-01

    In this paper, we analyse the delay performance of a point-to-multipoint cognitive radio network which is sharing the spectrum with a point-to-multipoint primary network. The channel is assumed to be independent but not identically distributed and has Nakagami-m fading. A constraint on the peak transmit power of the secondary user transmitter (SU-Tx) is also considered in addition to the peak interference power constraint. Based on the constraints, a power allocation scheme which requires knowledge of the instantaneous channel state information (CSI) of the interference links is derived. The SU-Tx is assumed to be equipped with a buffer and is modelled using the M/G/1 queueing model. Closed form expressions for the probability distribution function (PDF) and cumulative distribution function (CDF) of the packet transmission time is derived. Using the PDF, the expressions for the moments of transmission time are obtained. In addition, using the moments, the expressions for the performance measures such as the total average waiting time of packets and the average number of packets waiting in the buffer of the SU-Tx are also obtained. Numerical simulations corroborate the theoretical results. © 2012 IEEE.

  14. First Eigenmode Transmission by High Efficient CSI Estimation for Multiuser Massive MIMO Using Millimeter Wave Bands

    Directory of Open Access Journals (Sweden)

    Kazuki Maruta

    2016-07-01

    Full Text Available Drastic improvements in transmission rate and system capacity are required towards 5th generation mobile communications (5G. One promising approach, utilizing the millimeter wave band for its rich spectrum resources, suffers area coverage shortfalls due to its large propagation loss. Fortunately, massive multiple-input multiple-output (MIMO can offset this shortfall as well as offer high order spatial multiplexing gain. Multiuser MIMO is also effective in further enhancing system capacity by multiplexing spatially de-correlated users. However, the transmission performance of multiuser MIMO is strongly degraded by channel time variation, which causes inter-user interference since null steering must be performed at the transmitter. This paper first addresses the effectiveness of multiuser massive MIMO transmission that exploits the first eigenmode for each user. In Line-of-Sight (LoS dominant channel environments, the first eigenmode is chiefly formed by the LoS component, which is highly correlated with user movement. Therefore, the first eigenmode provided by a large antenna array can improve the robustness against the channel time variation. In addition, we propose a simplified beamforming scheme based on high efficient channel state information (CSI estimation that extracts the LoS component. We also show that this approximate beamforming can achieve throughput performance comparable to that of the rigorous first eigenmode transmission. Our proposed multiuser massive MIMO scheme can open the door for practical millimeter wave communication with enhanced system capacity.

  15. Minimax robust relay selection based on uncertain long-term CSI

    KAUST Repository

    Nisar, Muhammad Danish

    2014-02-01

    Cooperative communications via multiple relay nodes is known to provide the benefits of increase diversity and coverage. Simultaneous transmission via multiple relays, however, requires strong coordination between nodes either in terms of slot-based transmission or distributed space-time (ST) code implementation. Dynamically selecting a single best relay out of multiple relays and then using it alone for cooperative transmission alleviates the need for this strong coordination while still reaping the benefits of increased diversity and coverage. In this paper, we consider the design of relay selection (RS) under an imperfect knowledge of long-term channel state information (CSI) at the relay nodes, and we pursue minimax optimization to arrive at a robust RS approach that promises the best guarantee on the worst-case end-to-end signal-to-noise ratio (SNR). We provide some intuitive examples and extensive simulation results, not only in terms of worst-case SNR performance but also in terms of average bit-error-rate (BER) performance, to demonstrate the benefits of the proposed minimax robust RS scheme. © 2013 IEEE.

  16. PILA: Sub-Meter Localization Using CSI from Commodity Wi-Fi Devices

    Directory of Open Access Journals (Sweden)

    Zengshan Tian

    2016-10-01

    Full Text Available The aim of this paper is to present a new indoor localization approach by employing the Angle-of-arrival (AOA and Received Signal Strength (RSS measurements in Wi-Fi network. To achieve this goal, we first collect the Channel State Information (CSI by using the commodity Wi-Fi devices with our designed three antennas to estimate the AOA of Wi-Fi signal. Second, we propose a direct path identification algorithm to obtain the direct signal path for the sake of reducing the interference of multipath effect on the AOA estimation. Third, we construct a new objective function to solve the localization problem by integrating the AOA and RSS information. Although the localization problem is non-convex, we use the Second-order Cone Programming (SOCP relaxation approach to transform it into a convex problem. Finally, the effectiveness of our approach is verified based on the prototype implementation by using the commodity Wi-Fi devices. The experimental results show that our approach can achieve the median error 0.7 m in the actual indoor environment.

  17. Tsallis entropy and decoherence of CsI quantum pseudo dot qubit

    Science.gov (United States)

    Tiotsop, M.; Fotue, A. J.; Fotsin, H. B.; Fai, L. C.

    2017-05-01

    Polaron in CsI quantum pseudo dot under an electromagnetic field was considered, and the ground and first excited state energies were derived by employing the combining Pekar variational and unitary transformation methods. With the two-level system obtained, single qubit was envisioned and the decoherence was studied using non-extensive entropy (Tsallis entropy). Numerical results showed: (i) the increase (decrease) of the energy levels (period of oscillation) with the increase of chemical potential, the zero point of pseudo dot, cyclotron frequency, and transverse and longitudinal confinements; (ii) the Tsallis entropy evolved as a wave envelop that increase with the increase of non-extenxive parameter and with the increase of electric field strength, zero point of pseudo dot and cyclotron frequency the wave envelop evolve periodically with reduction of period; (iii) The transition probability increases from the boundary to the centre of the dot where it has its maximum value. It was also noted that the probability density oscillate with period T0 = ℏ / Δ Ε with the tunnelling of the chemical potential and zero point of the pseudo dot. These results are helpful in the control of decoherence in quantum systems and may also be useful for the design of quantum computers.

  18. The Present Development of CsI Rich Detectors for the ALICE Experiment at CERN

    CERN Document Server

    Nappi, E; Colonna, N; Di Mauro, A; Elia, D; Galantucci, L; Ghidini, B; Grimaldi, A; Goret, B; Monno, E; Paic, G; Piuz, François; Posa, F; Raynaud, J; Santiard, Jean-Claude; Tomasicchio, G; Williams, T D; Ljubicic, A; Tustonic, T; Stucchi, S

    1999-01-01

    The ALICE Collaboration plans to implement a 12m^2 array consisting of 7 proximity focussed C6F^14 liquid radiator RICH modules devoted to the particle identification in the momentum range: 1 GeV/c - 3.5 GeV/c for pions and kaons. A large area CSI-RICH prototype has been designed and built with the aim to validate the detector parameter assumptions made to predict the performance of the High Momentum Particle Identification System (HMPID) of the ALICE Experiment. The main elements of the prototype will be described with emphasis on the engineering solutions adopted. First results from the analysis of multitrack events recorded with this prototype exposed to hadron beams at the CERN SPS will be discussedList of FiguresFigure 1 General view of the ALICE lay-outFigure 2 Schematic layout of the fast CsI-RICHFigure 3 Perspective view of the HMPID layout with the seven RICH modules tilted according to their position with respect to the interaction vertex. The frame that supports the detectors is also shownFigure 4 ...

  19. Making space for criminalistics: Hans Gross and fin-de-siècle CSI.

    Science.gov (United States)

    Burney, Ian; Pemberton, Neil

    2013-03-01

    This article explores the articulation of a novel forensic object-the 'crime scene'-and its corresponding expert-the investigating officer. Through a detailed engagement with the work of the late nineteenth-century Austrian jurist and criminalist Hans Gross, it analyses the dynamic and reflexive nature of this model of 'CSI', emphasising the material, physical, psychological and instrumental means through which the crime scene as a delineated space, and its investigator as a disciplined agent operating within it, jointly came into being. It has a further, historiographic, aim: to move away from the commonplace emphasis in histories of forensics on fin-de-siècle criminology and toward its comparatively under-explored contemporary, criminalistics. In so doing, it opens up new ways of thinking about the crime scene as a defining feature of our present-day forensic culture that recognise its historical contingency and the complex processes at work in its creation and development. Copyright © 2012. Published by Elsevier Ltd.

  20. Charged-particle detection efficiencies of close-packed CsI arrays

    Science.gov (United States)

    Morfouace, P.; Lynch, W. G.; Tsang, M. B.

    2017-03-01

    Detector efficiency determination is essential to correct the measured yields and extract reliable cross sections of particles emitted in nuclear reactions. We investigate the efficiencies for measuring the full energies of light charged particle in arrays of CsI crystals employed in particle detection arrays such as HiRA, LASSA and MUST2. We perform these simulations with a GEANT4 Monte Carlo transport code implemented in the NPTool framework. Both Coulomb multiple scattering and nuclear reactions within the crystal can significantly reduce the efficiency of detecting the full energy of high energy particles. The calculated efficiencies decrease exponentially as a function of the range of the particle and are quite similar for both the hydrogen (p , d , t) and helium (3He, α) isotopes. The use of a close-packed array introduces significant position dependent efficiency losses at the interior boundaries between crystals that need to be considered in the design of an array and in the efficiency corrections of measured energy spectra.

  1. Long term stability of c-Si surface passivation using corona charged SiO2

    Science.gov (United States)

    Bonilla, Ruy S.; Reichel, Christian; Hermle, Martin; Hamer, Phillip; Wilshaw, Peter R.

    2017-08-01

    Recombination at the semiconductor surface continues to be a major limit to optoelectronic device performance, in particular for solar cells. Passivation films reduce surface recombination by a combination of chemical and electric field effect components. Dielectric films used for this purpose, however, must also accomplish optical functions at the cell surface. In this paper, corona charge is seen as a potential method to enhance the passivation properties of a dielectric film while maintaining its optical characteristics. It is observed that corona charge can produce extreme reductions in surface recombination via field effect, in the best case leading to lifetimes exceeding 5 ms at an injection of 1015 cm-3. For a 200 μm n-type 1 Ω cm c-Si wafer, this equates to surface recombination velocities below 0.65 cm/s and J0e values of 0.92 fA/cm2. The average improvement in passivation after corona charging gave lifetimes of 1-3 ms. This was stabilised for a period of 3 years by chemically treating the films to prevent water absorption. Surface recombination was kept below 7 cm/s, and J0e power in the cell (the loss in power output) when the passivation is kept better than 16 fA/cm2, and as high as 10% if front recombination is worse than 100 fA/cm2.

  2. The value of the Ki-67 proliferation marker as a prognostic factor in gastroenteropancreatic neuroendocrine tumours.

    Science.gov (United States)

    Foltyn, Wanda; Zajęcki, Wojciech; Marek, Bogdan; Kajdaniuk, Dariusz; Siemińska, Lucyna; Zemczak, Anna; Kos-Kudła, Beata

    2012-01-01

    Gastroenteropancreatic neuroendocrine tumours (GEP NETs) are a heterogenous group of tumours of various clinical presentations. Proliferative activity of tumour cells is an essential parameter determining the course of the disease and affecting the prognosis. The Ki-67 antigen is an important marker of cell proliferation, which shows activity in all the phases of the cell cycle, excluding the G0 phase. To assess the expression of Ki-67 in GEP NETs and to examine the association of Ki-67 with the stage of the tumour (tumour size, presence of metastases) and the hormonal function of the tumour. We included 61 patients with GEP NETs (25 males and 36 females aged between 20 and 82 years [mean age: 56 years]). The proliferative activity was examined in paraffin blocks containing surgically removed tumour samples and in core-needle biopsies of primary and metastatic tumours. The presence of the Ki-67 antigen was assessed by immunohistochemistry using MIB‑1 monoclonal antibodies. Based on the Ki-67 proliferative index we determined the tumour grade. In addition, we determined the tumour stage according to the TNM classification. In all the subjects we determined the levels of the non-specific NET marker (chromogranin A) and of specific NET markers (serotonin, insulin and gastrin in the blood and 5‑hydroxyindoleacetic acid [5‑HIAA] in 24-hour urine). The diagnoses of low-grade (Ki‑67 ≤ 2%), intermediate-grade (Ki-67 3-20%) and high-grade (Ki‑67 > 20%) NET were established in 38, 12 and 11 patients, respectively. Metastatic disease was diagnosed in 36/61 patients. A significantly higher expression of K-67 was observed in patients with metastatic disease (p = 0.01). A positive correlation was demonstrated between Ki-67 and the stage of the disease (p = 0.01) and between the histologic grade of the tumour and the stage of the disease (p = 0.01). No association between Ki-67 and the levels of chromogranin A, serotonin, insulin, gastrin and 5-HIAA was shown. There

  3. Sequence crystallization during isotherm evaporation of southern ...

    African Journals Online (AJOL)

    Sequence crystallization during isotherm evaporation of southern Algeria chott Baghdad natural brine. M Zatout, M Hacini, A.H. Hamzaoui, A M'nif. Abstract. Southern Algerian's natural brine sampled from chott Baghdad may be a source of mineral salts with a high economic value. These salts are recoverable by simple ...

  4. Control of evaporating complex fluids through electrowetting

    NARCIS (Netherlands)

    Mampallil Augustine, Dileep; Eral, Burak; van den Ende, Henricus T.M.; Mugele, Friedrich Gunther

    2012-01-01

    Evaporating drops of complex fluids such as colloidal suspensions and macromolecular solutions typically leave behind ring-shaped solid residues commonly known as coffee stains. Electrowetting-driven microfluidic flows allow for controlling this process. We present coffee stain suppression for

  5. Evaporative Lithography in Open Microfluidic Channel Networks

    KAUST Repository

    Lone, Saifullah

    2017-02-24

    We demonstrate a direct capillary-driven method based on wetting and evaporation of various suspensions to fabricate regular two-dimensional wires in an open microfluidic channel through continuous deposition of micro- or nanoparticles under evaporative lithography, akin to the coffee-ring effect. The suspension is gently placed in a loading reservoir connected to the main open microchannel groove on a PDMS substrate. Hydrophilic conditions ensure rapid spreading of the suspension from the loading reservoir to fill the entire channel length. Evaporation during the spreading and after the channel is full increases the particle concentration toward the end of the channel. This evaporation-induced convective transport brings particles from the loading reservoir toward the channel end where this flow deposits a continuous multilayered particle structure. The particle deposition front propagates backward over the entire channel length. The final dry deposit of the particles is thereby much thicker than the initial volume fraction of the suspension. The deposition depth is characterized using a 3D imaging profiler, whereas the deposition topography is revealed using a scanning electron microscope. The patterning technology described here is robust and passive and hence operates without an external field. This work may well become a launching pad to construct low-cost and large-scale thin optoelectronic films with variable thicknesses and interspacing distances.

  6. Intrinsic Angular Investigations on Metal Evaporated Tapes

    NARCIS (Netherlands)

    Samwel, E.O.; Samwel, E.O.; Bijl, D.B.; Lodder, J.C.; Popma, T.J.A.

    1996-01-01

    Demagnetisation compensated torque- and angle-dependent remanence measurements are presented on commercial and experimental metal evaporated tapes. The latter have been prepared in our laboratory on a mini-roll coater system. From these results the easy axes have been determined.

  7. Transhorizon Radiowave Propagation due to Evaporation Ducting ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 11; Issue 1. Transhorizon Radiowave Propagation due to Evaporation Ducting - The Effect of Tropospheric Weather Conditions on VHF and UHF Radio Paths Over the Sea. Salil David Gunashekar D R Siddle E M Warrington. General Article Volume 11 ...

  8. Spontaneous evaporation of the acetone drop

    Science.gov (United States)

    Dunin, S. Z.; Nagornov, O. V.

    2017-12-01

    The exact solution of the problem on evaporation of the acetone sessile drop at solid substrate is derived. The solution allows us to analyze the temperature field behavior at various thermodynamic parameters. The Marangoni forces are calculated in explicit form. The solution can be used to check numerical approaches for similar problems.

  9. Evaporative Lithography in Open Microfluidic Channel Networks.

    Science.gov (United States)

    Lone, Saifullah; Zhang, Jia Ming; Vakarelski, Ivan U; Li, Er Qiang; Thoroddsen, Sigurdur T

    2017-03-21

    We demonstrate a direct capillary-driven method based on wetting and evaporation of various suspensions to fabricate regular two-dimensional wires in an open microfluidic channel through continuous deposition of micro- or nanoparticles under evaporative lithography, akin to the coffee-ring effect. The suspension is gently placed in a loading reservoir connected to the main open microchannel groove on a PDMS substrate. Hydrophilic conditions ensure rapid spreading of the suspension from the loading reservoir to fill the entire channel length. Evaporation during the spreading and after the channel is full increases the particle concentration toward the end of the channel. This evaporation-induced convective transport brings particles from the loading reservoir toward the channel end where this flow deposits a continuous multilayered particle structure. The particle deposition front propagates backward over the entire channel length. The final dry deposit of the particles is thereby much thicker than the initial volume fraction of the suspension. The deposition depth is characterized using a 3D imaging profiler, whereas the deposition topography is revealed using a scanning electron microscope. The patterning technology described here is robust and passive and hence operates without an external field. This work may well become a launching pad to construct low-cost and large-scale thin optoelectronic films with variable thicknesses and interspacing distances.

  10. optimal evaporating and condensing temperatures of organic

    African Journals Online (AJOL)

    user

    2017-01-01

    Jan 1, 2017 ... However, the study further showed that the evaporating temperature (ET) and condensing temperature (CT) affect the thermal performance and net power output of the cycles. Dai et al.[20]conducted parametric optimisation of ORC with exergy efficiency. He et al. [21] considered the optimisation of a simple.

  11. Experiments on Evaporative Emissions in Ventilated Rooms

    DEFF Research Database (Denmark)

    Topp, Claus; Nielsen, Peter V.; Heiselberg, Per

    In many new buildings the indoor air quality is affected by emissions of volatile organic compounds (VOCs) from building materials. The emission process may be controlled either by diffusion inside the material or evaporation from the surface but it always involves mass transfer across the boundary...

  12. Evaporation Controlled Emission in Ventilated Rooms

    DEFF Research Database (Denmark)

    Topp, Claus; Nielsen, Peter V.; Heiselberg, Per

    -scale ventilated room when the emission is fully or partly evaporation controlled. The objective of the present research work has been to investigate the change of emission rates from small-scale experiments to full-scale ventilated rooms and to investigate the influence of the local air velocity field near...

  13. Evaluating the hydrological consistency of evaporation products

    KAUST Repository

    Lopez Valencia, Oliver Miguel

    2017-01-18

    Advances in space-based observations have provided the capacity to develop regional- to global-scale estimates of evaporation, offering insights into this key component of the hydrological cycle. However, the evaluation of large-scale evaporation retrievals is not a straightforward task. While a number of studies have intercompared a range of these evaporation products by examining the variance amongst them, or by comparison of pixel-scale retrievals against ground-based observations, there is a need to explore more appropriate techniques to comprehensively evaluate remote-sensing-based estimates. One possible approach is to establish the level of product agreement between related hydrological components: for instance, how well do evaporation patterns and response match with precipitation or water storage changes? To assess the suitability of this "consistency"-based approach for evaluating evaporation products, we focused our investigation on four globally distributed basins in arid and semi-arid environments, comprising the Colorado River basin, Niger River basin, Aral Sea basin, and Lake Eyre basin. In an effort to assess retrieval quality, three satellite-based global evaporation products based on different methodologies and input data, including CSIRO-PML, the MODIS Global Evapotranspiration product (MOD16), and Global Land Evaporation: the Amsterdam Methodology (GLEAM), were evaluated against rainfall data from the Global Precipitation Climatology Project (GPCP) along with Gravity Recovery and Climate Experiment (GRACE) water storage anomalies. To ensure a fair comparison, we evaluated consistency using a degree correlation approach after transforming both evaporation and precipitation data into spherical harmonics. Overall we found no persistent hydrological consistency in these dryland environments. Indeed, the degree correlation showed oscillating values between periods of low and high water storage changes, with a phase difference of about 2–3 months

  14. Three-dimensional organization of pKi-67: a comparative fluorescence and electron tomography study using FluoroNanogold.

    Science.gov (United States)

    Cheutin, Thierry; O'Donohue, Marie-Françoise; Beorchia, Adrien; Klein, Christophe; Kaplan, Hervé; Ploton, Dominique

    2003-11-01

    The monoclonal antibody (MAb) Ki-67 is routinely used in clinical studies to estimate the growth fraction of tumors. However, the role of pKi-67, the protein detected by the Ki-67 MAb, remains elusive, although some biochemical data strongly suggest that it might organize chromatin. To better understand the functional organization of pKi-67, we studied its three-dimensional distribution in interphase cells by confocal microscopy and electron tomography. FluoroNanogold, a single probe combining a dense marker with a fluorescent dye, was used to investigate pKi-67 organization at the optical and ultrastructural levels. Observation by confocal microscopy followed by 3D reconstruction showed that pKi-67 forms a shell around the nucleoli. Double labeling experiments revealed that pKi-67 co-localizes with perinucleolar heterochromatin. Electron microscopy studies confirmed this close association and demonstrated that pKi-67 is located neither in the fibrillar nor in the granular components of the nucleolus. Finally, spatial analyses by electron tomography showed that pKi-67 forms cords 250-300 nm in diameter, which are themselves composed of 30-50-nm-thick fibers. These detailed comparative in situ analyses strongly suggest the involvement of pKi-67 in the higher-order organization of perinucleolar chromatin.

  15. The expression and significance of p53 protein and Ki-67 protein in pterygium

    Directory of Open Access Journals (Sweden)

    Ljubojević Vesna

    2016-01-01

    Full Text Available Background/Aim. Pterygium is considered to be a degenerative disease of the conjunctiva, however, the presence of tumor markers in pterygium reinforces the hypothesis that this lesion is similar to tumor. Inactivation of p53 function removes an obstacle to increased proliferation. Factors affecting the prevalence of p53 expression in pterygium deserve investigation. The aim of the study was to investigate the expression of p53 and Ki-67 proteins in pterygium and normal conjunctiva, the effects of gender and age on p53 expression, and the relationship between the expression of p53 and Ki-67 proteins. Methods. A total of 34 samples of pterygium and 34 samples of the normal conjunctiva were analyzed. The samples were studied by immunohistochemistry using antibodies against p53 and Ki-67. Results. Totally 15 (44% samples of pterygia were p53 positive. Correlations between the expression of p53 protein and sex, and age were not established. The number of Ki-67 positive cells in pterygium (9.74% was significantly higher than the number of Ki-67 positive cells in the normal conjunctiva (1.74%, (p = 0.001. Between the expression of p53 protein and Ki-67 protein in pterygium there was a significant positive correlation (p = 0.000. Conclusion. The prevalence of p53 positive samples of pterygium was 44%. The influence of sex and age on p53 protein expression in pterygium was not found. The increased proliferative acivity was present in the epithelium of pterygium. The expression of Ki-67 protein is associated with the expression of p53 protein in pterygium. The findings of our study support the thesis of pterygium as tissue growth disorder.

  16. Major prognostic role of Ki67 in localized adrenocortical carcinoma after complete resection.

    Science.gov (United States)

    Beuschlein, Felix; Weigel, Jens; Saeger, Wolfgang; Kroiss, Matthias; Wild, Vanessa; Daffara, Fulvia; Libé, Rosella; Ardito, Arianna; Al Ghuzlan, Abir; Quinkler, Marcus; Oßwald, Andrea; Ronchi, Cristina L; de Krijger, Ronald; Feelders, Richard A; Waldmann, Jens; Willenberg, Holger S; Deutschbein, Timo; Stell, Anthony; Reincke, Martin; Papotti, Mauro; Baudin, Eric; Tissier, Frédérique; Haak, Harm R; Loli, Paola; Terzolo, Massimo; Allolio, Bruno; Müller, Hans-Helge; Fassnacht, Martin

    2015-03-01

    Recurrence of adrenocortical carcinoma (ACC) even after complete (R0) resection occurs frequently. The aim of this study was to identify markers with prognostic value for patients in this clinical setting. From the German ACC registry, 319 patients with the European Network for the Study of Adrenal Tumors stage I-III were identified. As an independent validation cohort, 250 patients from three European countries were included. Clinical, histological, and immunohistochemical markers were correlated with recurrence-free (RFS) and overall survival (OS). Although univariable analysis within the German cohort suggested several factors with potential prognostic power, upon multivariable adjustment only a few including age, tumor size, venous tumor thrombus (VTT), and the proliferation marker Ki67 retained significance. Among these, Ki67 provided the single best prognostic value for RFS (hazard ratio [HR] for recurrence, 1.042 per 1% increase; P < .0001) and OS (HR for death, 1.051; P < .0001) which was confirmed in the validation cohort. Accordingly, clinical outcome differed significantly between patients with Ki67 <10%, 10-19%, and ≥20% (for the German cohort: median RFS, 53.2 vs 31.6 vs 9.4 mo; median OS, 180.5 vs 113.5 vs 42.0 mo). Using the combined cohort prognostic scores including tumor size, VTT, and Ki67 were established. Although these scores discriminated slightly better between subgroups, there was no clinically meaningful advantage in comparison with Ki67 alone. This largest study on prognostic markers in localized ACC identified Ki67 as the single most important factor predicting recurrence in patients following R0 resection. Thus, evaluation of Ki67 indices should be introduced as standard grading in all pathology reports of patients with ACC.

  17. Screening for precancerous anal lesions with P16/Ki67 immunostaining in HIV-infected MSM.

    Directory of Open Access Journals (Sweden)

    Sergio Serrano-Villar

    Full Text Available Screening of anal cancer in HIV-infected MSM with anal cytology results in high rates of false positive results and elevated burden of high-resolution anoscopies. High-risk HPV up-regulates p16 and Ki67 expression in epithelial cells. We assessed the usefulness of P16/Ki-67 immunostaining cytology for the diagnosis of precancerous anal lesions.Cross-sectional multicenter study. Concomitant anal liquid cytology with p16/Ki-67 immunostaining and HRA with biopsy of acetowhite lugol-negative lesions was performed in HIV-infected MSM. We compared the diagnostic performance of an abnormal anal cytology and p16/Ki-67 immunostaining relative to HRA-guided biopsy by logistic regression and comparison of ROC areas.We included 328 HIV-infected MSM. HSIL was histologically diagnosed in 72 subjects (25.1%, and 2 (0.6% were diagnosed with anal cancer. An abnormal cytology showed a sensitivity of 95.6% and a specificity of 58.8% for the diagnosis of biopsy-proven HSIL. P16/Ki67 positivity was associated with the presence of biopsy-proven HSIL (P trend = 0.004 but with low sensitivity (41.2% and specificity (71%. The combination of standard cytology with P16/Ki67 immunostaining did not increment the predictive value of standard cytology alone (AUC 0.685 vs. 0.673, respectively, P = 0.688.In HIV-infected MSM P16/Ki67 immunostaining does not improve the diagnostic accuracy of anal cytology, which shows a high sensitivity yet poor specificity. Other approaches aimed at improving the diagnostic accuracy of current techniques for the diagnostic of precancerous HSIL are warranted.

  18. Evaporation characteristics of ETBE-blended gasoline

    Energy Technology Data Exchange (ETDEWEB)

    Okamoto, Katsuhiro, E-mail: okamoto@nrips.go.jp [National Research Institute of Police Science, 6-3-1 Kashiwanoha, Kashiwa, Chiba 277-0882 (Japan); Hiramatsu, Muneyuki [Yamanashi Prefectural Police H.Q., 312-4 Kubonakajima, Isawa-cho, Usui, Yamanashi 406-0036 (Japan); Hino, Tomonori; Otake, Takuma [Metropolitan Police Department, 2-1-1 Kasumigaseki, Chiyoda-ku, Tokyo 100-8929 (Japan); Okamoto, Takashi; Miyamoto, Hiroki; Honma, Masakatsu; Watanabe, Norimichi [National Research Institute of Police Science, 6-3-1 Kashiwanoha, Kashiwa, Chiba 277-0882 (Japan)

    2015-04-28

    Highlights: • We chose 8-component hydrocarbon mixture as a model gasoline, and defined the molar mass of gasoline. • We proposed an evaporation model assuming a 2-component mixture of gasoline and ETBE. • We predicted the change in the vapor pressure of ETBE-blended gasoline by evaporation. • The vapor pressures were measured and compared as a means of verifying the model. • We presented the method for predicting flash points of the ETBE-blended gasoline. - Abstract: To reduce greenhouse gas emissions, which contribute to global warming, production of gasoline blended with ethyl tert-buthyl ether (ETBE) is increasing annually. The flash point of ETBE is higher than that of gasoline, and blending ETBE into gasoline will change the flash point and the vapor pressure. Therefore, it is expected that the fire hazard caused by ETBE-blended gasoline would differ from that caused by normal gasoline. The aim of this study was to acquire the knowledge required for estimating the fire hazard of ETBE-blended gasoline. Supposing that ETBE-blended gasoline was a two-component mixture of gasoline and ETBE, we developed a prediction model that describes the vapor pressure and flash point of ETBE-blended gasoline in an arbitrary ETBE blending ratio. We chose 8-component hydrocarbon mixture as a model gasoline, and defined the relation between molar mass of gasoline and mass loss fraction. We measured the changes in the vapor pressure and flash point of gasoline by blending ETBE and evaporation, and compared the predicted values with the measured values in order to verify the prediction model. The calculated values of vapor pressures and flash points corresponded well to the measured values. Thus, we confirmed that the change in the evaporation characteristics of ETBE-blended gasoline by evaporation could be predicted by the proposed model. Furthermore, the vapor pressure constants of ETBE-blended gasoline were obtained by the model, and then the distillation curves were

  19. The evaporative function of cockroach hygroreceptors.

    Directory of Open Access Journals (Sweden)

    Harald Tichy

    Full Text Available Insect hygroreceptors associate as antagonistic pairs of a moist cell and a dry cell together with a cold cell in small cuticular sensilla on the antennae. The mechanisms by which the atmospheric humidity stimulates the hygroreceptive cells remain elusive. Three models for humidity transduction have been proposed in which hygroreceptors operate either as mechanical hygrometers, evaporation detectors or psychrometers. Mechanical hygrometers are assumed to respond to the relative humidity, evaporation detectors to the saturation deficit and psychrometers to the temperature depression (the difference between wet-bulb and dry-bulb temperatures. The models refer to different ways of expressing humidity. This also means, however, that at different temperatures these different types of hygroreceptors indicate very different humidity conditions. The present study tested the adequacy of the three models on the cockroach's moist and dry cells by determining whether the specific predictions about the temperature-dependence of the humidity responses are indeed observed. While in previous studies stimulation consisted of rapid step-like humidity changes, here we changed humidity slowly and continuously up and down in a sinusoidal fashion. The low rates of change made it possible to measure instantaneous humidity values based on UV-absorption and to assign these values to the hygroreceptive sensillum. The moist cell fitted neither the mechanical hygrometer nor the evaporation detector model: the temperature dependence of its humidity responses could not be attributed to relative humidity or to saturation deficit, respectively. The psychrometer model, however, was verified by the close relationships of the moist cell's response with the wet-bulb temperature and the dry cell's response with the dry-bulb temperature. Thus, the hygroreceptors respond to evaporation and the resulting cooling due to the wetness or dryness of the air. The drier the ambient air

  20. Tank 26F-2F Evaporator Study

    Energy Technology Data Exchange (ETDEWEB)

    Adu-Wusu, K.

    2012-12-19

    Tank 26F supernate sample was sent by Savannah River Remediation to Savannah River National Laboratory for evaporation test to help understand the underlying cause of the recent gravity drain line (GDL) pluggage during operation of the 2F Evaporator system. The supernate sample was characterized prior to the evaporation test. The evaporation test involved boiling the supernate in an open beaker until the density of the concentrate (evaporation product) was between 1.4 to 1.5 g/mL. It was followed by filtering and washing of the precipitated solids with deionized water. The concentrate supernate (or concentrate filtrate), the damp unwashed precipitated solids, and the wash filtrates were characterized. All the precipitated solids dissolved during water washing. A semi-quantitative X-ray diffraction (XRD) analysis on the unwashed precipitated solids revealed their composition. All the compounds with the exception of silica (silicon oxide) are known to be readily soluble in water. Hence, their dissolution during water washing is not unexpected. Even though silica is a sparingly water-soluble compound, its dissolution is also not surprising. This stems from its small fraction in the solids as a whole and also its relative freshness. Assuming similar supernate characteristics, flushing the GDL with water (preferably warm) should facilitate dissolution and removal of future pluggage events as long as build up/aging of the sparingly soluble constituent (silica) is limited. On the other hand, since the amount of silica formed is relatively small, it is quite possible dissolution of the more soluble larger fraction will cause disintegration or fragmentation of the sparingly soluble smaller fraction (that may be embedded in the larger soluble solid mass) and allow its removal via suspension in the flushing water.

  1. THE USE OF POROUS CERAMICS FOR EVAPORATIVE AND EVAPORATIVE – VAPOR –COMPRESSION SYSTEMS

    Directory of Open Access Journals (Sweden)

    Cheban D.N.

    2013-04-01

    Full Text Available The use of natural evaporative cooling is one of technical solutions of problem of energy efficiency in air conditioning systems. The use of evaporative cooling in the first combined cooling stage allows reducing the load on the condenser of the cooling machine due to reducing of the condensing temperature. This combination allows the use of this type of system in any climatic conditions, including regions with small water resources. Multi-porous ceramic structure is used in evaporative air coolers and water coolers in this case. The objective of this paper is to show advantages of the using of porous ceramic as a working attachment, and to show advantages of the proposed scheme of compression-evaporation systems in comparison with standard vapor compression systems. Experimental research proved the fact, that in the film mode cooling efficiency of air flow is between EA=0,6÷0,7 and is slightly dependent of water flow. For countries with hot and dry climate where reserves of water are limited, it is recommended to use cyclical regime with EA≈0,65 value, or to use channel regime with a value of EA≈0,55. This leads to considerable energy savings. It has been determined, that combined air conditioning system is completely closed on the consumption of water at the parameters of the outside air equal to tA =32ºC and XA>13g/kg (in system with direct evaporative cooling machine, and tA=32ºC and XA>12g/kg (in system with indirect evaporative cooling machine. With these parameters, the cost of water in evaporative cooling stage can be fully compensated by condensate from the evaporator chiller.

  2. Flow cytometry vs. Ki67 labelling index in breast cancer: a prospective evaluation of 181 cases.

    Science.gov (United States)

    Martínez-Arribas, F; Núñez, M J; Piqueras, V; Lucas, A R; Sánchez, J; Tejerina, A; Schneider, J

    2002-01-01

    Excessive proliferation is one of the first steps in oncogenic activation and one of the most important biological features defining the aggressiveness of tumors. Quantifying the proportion of tumor cells in S-phase by means of flow cytometry has shown, in the past, to be useful for defining high-risk subgroups in breast cancer. Several antigens closely associated with proliferation are also detectable by means of immunohistochemistry, offering in theory an easy to perform and cheap alternative to flow cytometry for measuring proliferation. To test this hypothesis, we compared both methods prospectively in a series of breast cancers. We studied the proliferation rate of 181 breast cancers (152 ductal infiltrating, 17 lobular infiltrating, 12 other histological varieties), operated upon at our institution, by means of flow cytometry and the Ki67 labelling index, using the MIBI antibody. Ploidy (expressed as DNA content or DNA-index), S-phase fraction and the Ki67 labelling index were the variables of the study. The S-phase fraction was considered separately for diploid and aneuploid tumors, following the 1992 Maine Consensus guidelines and was judged abnormally elevated if higher than the 75th percentile for each group. The Ki67 labelling index was expressed as percent positive tumor cells, positive cells being those showing specific nuclear staining. DNA-ploidy and the Ki67 labelling index could be evaluated in all tumors. Of the total, 96 (53%) were diploid and 85 (47%) aneuploid. S-phase fraction could be measured in 172 out of the 181 tumors (95%). The 75th percentile cut-offs for diploid and aneuploid tumors were 9.9% and 15.8%, respectively. We found a significant correlation beween rising DNA content and increasing Ki67 index (r = 0.18; p = 0.022), as well as between the percentage of cells in S-phase of the whole tumor population and Ki67 (r = 0.22; p = 0.0055). A Ki67 cut-off of 50% or higher identified most aneuploid tumors, or a small group of diploid

  3. PENDIDIKAN KARAKTER KI HADJAR DEWANTARA: STUDI KRITIS PEMIKIRAN KARAKTER DAN BUDI PEKERTI DALAM TINJAUAN ISLAM

    Directory of Open Access Journals (Sweden)

    Muthoifin Muthoifin

    2015-12-01

    Full Text Available What an importance of character, Ki Hadjar makes it as a soul from the concept of his education. Even the government admitted, almost all national educational concepts referring to his idea. the focus of this issue is how the concept of Ki Hadjar's character in the Islamic view. The method used is historical approach, by the technique of content analysis, descriptive and comparative. The data is analyzed to be conclusion from the existing phenomenon. The results of the study, Ki Hadjar's idea about the character is not found the base that is closely related to faith, but rather stands on a universal national identity, it can be seen that the Ki Hadjar wants the Indonesian nation has a good attitude and personality and remain to stand on the personality of the Indonesian nation that has a distinctive culture and personality. While the characters in Islam can not be separated with monotheism and faith.   Keywords: character; Ki Hadjar Dewantara; budi pekerti; Islam.

  4. Studies on evaporation from the north Indian Ocean

    Digital Repository Service at National Institute of Oceanography (India)

    Rao, Lakshmana G.R.; VeenaDevi, Y.; Reddy, Gopala K.; Prasad, A.L.N.

    Evaporation from the surface of the North Indian Ocean is estimated following the aerodynamic approach The influence of the southwest monsoon and the northeast monsoon is significant giving rise to maximum evaporation from the sea surface due...

  5. An Investigation of Graduate Scientists' Understandings of Evaporation and Boiling.

    Science.gov (United States)

    Goodwin, Alan; Orlik, Yuri

    2000-01-01

    Uses a video presentation of six situations relating to the evaporation and boiling of liquids and the escape of dissolved gases from solution and investigates graduate scientists' understanding of the concepts of boiling and evaporation. (Author/YDS)

  6. Regional Differences of Metabolic Response During Dynamic Incremental Exercise by (31)P-CSI.

    Science.gov (United States)

    Kaneko, Yasuhisa; Kime, Ryotaro; Hongo, Yoshinori; Ohno, Yusuke; Sakamoto, Ayumi; Katsumura, Toshihito

    The aim of this study was to detect the differences in muscle metabolic response of the quadriceps during incremental dynamic knee exercise using regional (31)Phosphorus Chemical Shift Imaging ((31)P-CSI). Sixteen healthy men participated in this study (age 28 ± 5 years, height 171.4 ± 3.9 cm, weight 67.1 ± 9.8 kg). The experiments were carried out with a 1.5-T superconducting magnet with a 5-in. diameter circular surface coil. The subjects performed isometric unilateral knee extension exercise to detect their maximum voluntary contraction (MVC) in prone position. Then they performed dynamic unilateral knee extension exercise in the magnet at 10, 20, 30 and 40 % of their MVC with the transmit-receive coil placed under the right quadriceps. The subjects pulled down a rope with the adjusted weight attached to the ankle at a frequency of 0.5 Hz for 380 s. Intracellular pH (pHi) was calculated from the median chemical shift of the inorganic phosphate (Pi) peak relative to phosphocreatine (PCr). The quadriceps were divided into three regions, (1) medial, (2) anterior, (3) lateral, and in comparison, there was no significant difference in Pi/PCr nor in pHi between regions, except Pi/PCr of the medial region was significantly higher than the anterior region at maximum intensity (p < 0.05). These results suggest that regional muscle metabolic response is similar in the quadriceps except at maximum intensity.

  7. Evaporation from the shallow Lake Massaciuccoli (Tuscany, Italy) studied using stable isotopes and evaporation pan data

    Science.gov (United States)

    Baneschi, I.; Gonfiantini, R.; Guidi, M.

    2009-04-01

    Oxygen and hydrogen isotope variations monitored in Lake Massaciuccoli (7 km2, 2 m deep, seasonally variable water level) during summer 2008, were compared with those observed in a Class A evaporation pan (diameter 120.6 cm, depth 25.4 cm) placed on the lake eastern shore. Air temperature, pressure, relative humidity, wind speed and direction, solar radiation, water temperature in the lake and the pan were also measured. The pluviometer indicated that no precipitation occurred during the study period. The pan was initially filled with groundwater up to the level of 19.2 cm (219 L), depleted in heavy isotopes with respect to tha lake water. Sodium chloride was added up to the concentration of 1 g×L-1, which is assumed do not affect significantly the evaporation rate till the water volume is reduced to less than 10 %. The Cl- concentration was used to provide an estimation of the evaporated water fraction, in addition to the micrometer measuring the water level variations. The pan water was sampled every 2-3 days and Cl- and stable isotopes determined. The set of stable isotope and evaporation data enabled us to compute the parameters governing the evaporation process and the isotopic exchanges with the atmospheric moisture, according to the procedure proposed by Gonfiantini (1986). The values were applied to test three working hypotheses of water balance of Lake Massaciuccoli: (i) surface inflow and outflow of liquid water are negligible and only evaporation is important; (ii) the inflow is negligible and outflow and evaporation are both significant; (iii) the three terms of balance are all important but the losses by evaporation and outflow exceed inflow (as the lake water level was decreasing). Water exchanges with groundwater are considered negligible. The best agreement between lake and pan data was obtained with the second hypothesis, for which the fraction of water removed by evaporation was estimated to be about 40 % ot he total water losses. This residual

  8. 7 CFR 58.913 - Evaporators and vacuum pans.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Evaporators and vacuum pans. 58.913 Section 58.913....913 Evaporators and vacuum pans. All equipment used in the removal of moisture from milk or milk... Sanitary Standards for Milk and Milk Products Evaporators and Vacuum Pans. ...

  9. Modeling of Evaporation Losses in Sewage Sludge Drying Bed ...

    African Journals Online (AJOL)

    Modeling of Evaporation Losses in Sewage Sludge Drying Bed. JI Obianyo, JC Agunwamba. Abstract. A model for evaporation losses in sewage sludge drying bed was derived from first principles. This model was developed based on the reasoning that the rate at which evaporation is taking place is directly proportional to ...

  10. Method of freshening salt water in a saline evaporator

    Energy Technology Data Exchange (ETDEWEB)

    Khalikov, T.T.

    1982-01-01

    A method is described for freshening salt water in a saline evaporator by heating the water, blowing the evaporation surface with air and condensation of the distillate. In order to reduce heat losses in the air freshener before blowing, the evaporation surfaces are preliminarily heated.

  11. EVAPORATIVE COOLING - CONCEPTUAL DESIGN FOR ATLAS SCT

    CERN Document Server

    Niinikoski, T O

    1998-01-01

    The conceptual design of an evaporative two-phase flow cooling system for the ATLAS SCT detector is described, using perfluorinated propane (C3F8) as a coolant. Comparison with perfluorinated butane (C4F10) is made, although the detailed design is presented only for C3F8. The two-phase pressure drop and heat transfer coefficient are calculated in order to determine the dimensions of the cooling pipes and module contacts for the Barrel SCT. The region in which the flow is homogeneous is determined. The cooling cycle, pipework, compressor, heat exchangers and other main elements of the system are calculated in order to be able to discuss the system control, safety and reliability. Evaporative cooling appears to be substantially better than the binary ice system from the point of view of safety, reliability, detector thickness, heat transfer coefficient, cost and simplicity.

  12. Thermodynamic Modeling of Savannah River Evaporators

    Energy Technology Data Exchange (ETDEWEB)

    Weber, C.F.

    2001-08-02

    A thermodynamic model based on the code SOLGASMIX is developed to calculate phase equilibrium in evaporators and related tank wastes at the Savannah River Site (SRS). This model uses the Pitzer method to calculate activity coefficients, and many of the required Pitzer parameters have been determined in the course of this work. Principal chemical species in standard SRS simulant solutions are included, and the temperature range for most parameters has been extended above 100 C. The SOLGASMIX model and calculations using the code Geochemists Workbench are compared to actual solubility data including silicate, aluminate, and aluminosilicate solutions. In addition, SOLGASMIX model calculations are also compared to transient solubility data involving SRS simulant solutions. These comparisons indicate that the SOLGASMIX predictions closely match reliable data over the range of temperature and solution composition expected in the SRS evaporator and related tanks. Predictions using the Geochemists Workbench may be unreliable, due primarily to the use of an inaccurate activity coefficient model.

  13. Black hole evaporation rates without spacetime.

    Science.gov (United States)

    Braunstein, Samuel L; Patra, Manas K

    2011-08-12

    Verlinde recently suggested that gravity, inertia, and even spacetime may be emergent properties of an underlying thermodynamic theory. This vision was motivated in part by Jacobson's 1995 surprise result that the Einstein equations of gravity follow from the thermodynamic properties of event horizons. Taking a first tentative step in such a program, we derive the evaporation rate (or radiation spectrum) from black hole event horizons in a spacetime-free manner. Our result relies on a Hilbert space description of black hole evaporation, symmetries therein which follow from the inherent high dimensionality of black holes, global conservation of the no-hair quantities, and the existence of Penrose processes. Our analysis is not wedded to standard general relativity and so should apply to extended gravity theories where we find that the black hole area must be replaced by some other property in any generalized area theorem.

  14. Strong evaporation of a polyatomic gas

    Science.gov (United States)

    Cercignani, C.

    The problems arising in connection with the study of the structure of a jet evaporating into a vacuum are investigated. A kinetic theory description is given of the vapor motion into a vacuum for arbitrarily strong evaporation rates at an interphase boundary of circular shape. The solution of the problem is studied in three separate regions, in each of which the dependence of the solution on the space variables and the mean freepath is different. The theory that steady supersonic flows are impossible in a one-dimensional flow (Cercigani, 1980; Authur and Cercignani, 1980) is discussed. Finally, the analysis of the region near the wall is extended to a polyatomic gas, using the trimodal ansatz for the molecular distribution function of a monatomic gas. The main results of the analysis performed by Ytrehus for a monatomic gas (1975, 1977) are confirmed. New results concerning the discrepancy between internal and translational temperatures near the surface are presented.

  15. Long-term lowering of tumour interstitial fluid pressure reduces Ki-67 expression.

    Science.gov (United States)

    Hofmann, Matthias; Schultz, Maike; Bernd, August; Bereiter-Hahn, Jürgen; Kaufmann, Roland; Kippenberger, Stefan

    2007-01-01

    High tumour interstitial fluid pressure (TIFP) is a characteristic of most solid tumours. Recent data give first evidence that mechanical stretch induced by TIFP triggers proliferation in solid tumours. In the present study we compared two protocols of TIFP reduction on the expression of the tumour proliferation marker Ki-67: (a) short-term lowering of TIFP by a singular puncture and (b) long-term lowering of TIFP by catheterization. Utilizing two experimental tumours (A431, A549) it was found that the TIFP broke down rapidly after a singular puncture but recovered within 6h. In case of permanent catheterization no TIFP recovery was observed. After 24h tumours were excised and stained against the proliferation marker Ki-67. While a singular puncture had no effect catheterized tumours showed a significant decrease in Ki-67 expression. Our data suggest that long-term lowering of TIFP is required to reduce tumour proliferation.

  16. Pendidikan ideal perspektif Tagore dan Ki Hajar Dewantara dalam pembentukan karakter peserta didik

    Directory of Open Access Journals (Sweden)

    Marzuki Marzuki

    2017-01-01

    Full Text Available The research aims to study the thought of Rabindranath Tagore and Ki Hajar Dewantara with the ideal education related in formation of students character. This research is a literature review using content analysis approach. Sources of data in the form of primary data and secondary data on thought of two leaders in education. Data were analyzed qualitatively with the inductive approach. The results showed that 1 Rabindranath Tagore saw education based on freedom and love. Learning approach undertaken by Rabindranath Tagore in the education system is experiential learning; 2 Ki Hajar Dewantara developed a Among system in education which is an effort to advance the development of morality (inner strength, mind (intellect, and physical students; and 3 there is a link between thought of Rabindranath Tagore and thought of Ki Hajar Dewantara on looking at the education and development of ideal education system.

  17. New insights into saline water evaporation from porous media: Complex interaction between evaporation rates, precipitation, and surface temperature

    Science.gov (United States)

    Shokri-Kuehni, Salomé M. S.; Vetter, Thomas; Webb, Colin; Shokri, Nima

    2017-06-01

    Understanding salt transport and deposition patterns during evaporation from porous media is important in many engineering and hydrological processes such as soil salinization, ecosystem functioning, and land-atmosphere interaction. As evaporation proceeds, salt concentration increases until it exceeds solubility limits, locally, and crystals precipitate. The interplay between transport processes, crystallization, and evaporation influences where crystallization occurs. During early stages, the precipitated salt creates an evolving porous structure affecting the evaporation kinetics. We conducted a comprehensive series of experiments to investigate how the salt concentration and precipitation influence evaporation dynamics. Our results illustrate the contribution of the evolving salt crust to the evaporative mass losses. High-resolution thermal imaging enabled us to investigate the complex temperature dynamics at the surface of precipitated salt, providing further confirmation of salt crust contribution to the evaporation. We identify different phases of saline water evaporation from porous media with the corresponding dominant mechanisms in each phase and extend the physical understanding of such processes.

  18. A method for simultaneous quantification of monoclonal antibody Ki-67 and DNA content by flow cytometry. Application to breast carcinomas.

    Science.gov (United States)

    Gorisse, M C; Venteo, L; Pluot, M

    1999-02-01

    To seek a method assessing Ki-67 immunostaining and DNA content by flow cytometry simultaneously. The murine monoclonal antibody Ki-67 (Ki) identifies a nuclear protein complex expressed by all nonquiescent tumor cells. Since the antigen detected by Ki is quite labile in most fixation and embedding protocols, a new method for simultaneous quantification of nuclear Ki immunofluorescence and DNA content by flow cytometry was developed. Unfixed, solid tumor cells are permeabilized only with saponin to preserve Ki antigen. The percentage of Ki-positive cell subpopulations calculated by subtraction of the related aspecific fixation histogram gives optimal results more rapidly than by cytogram analysis. Application to breast carcinoma shows the feasibility of the method. Significant correlations between Ki staining and the S-phase fraction were observed. Mean Ki labelling rates of aneuploid tumors were significantly higher than those of the diploid tumors, and significant differences between histologic types were found. This technique can be considered a fast, sensitive and optimal method to evaluate the proliferative activity of breast carcinomas and possibly of other solid tumors in a department of pathology.

  19. Modeling and simulation of direct contact evaporators

    OpenAIRE

    Campos F.B.; Lage P. L. C.

    2001-01-01

    A dynamic model of a direct contact evaporator was developed and coupled to a recently developed superheated bubble model. The latter model takes into account heat and mass transfer during the bubble formation and ascension stages and is able to predict gas holdup in nonisothermal systems. The results of the coupled model, which does not have any adjustable parameter, were compared with experimental data. The transient behavior of the liquid-phase temperature and the vaporization rate under q...

  20. Correlation of apparent diffusion coefficient with Ki-67 proliferation index in grading meningioma.

    Science.gov (United States)

    Tang, Yi; Dundamadappa, Sathish K; Thangasamy, Senthur; Flood, Thomas; Moser, Richard; Smith, Thomas; Cauley, Keith; Takhtani, Deepak

    2014-06-01

    A noninvasive method to predict aggressiveness of high-grade meningiomas would be desirable because it would help anticipate tumor recurrence and improve tumor management and the treatment outcomes. The Ki-67 protein is a marker of tumor proliferation, and apparent diffusion coefficient (ADC) is related to tumor cellularity. Therefore, we sought to determine whether there is a statistically significant correlation between ADC and Ki-67 values in meningiomas and whether ADC values can differentiate various meningioma subtypes. MRI examinations and histopathology of 68 surgically treated meningiomas were retrospectively reviewed. Mean ADC values were derived from diffusion imaging. Correlation coefficients were calculated for mean ADC and Ki-67 proliferation index values using linear regression. An independent unpaired Student t test was used to compare the ADC and Ki-67 proliferation index values from low-grade and more aggressive meningiomas. A statistically significant inverse correlation was found between ADC and Ki-67 proliferation index for low-grade and aggressive meningiomas (r(2) = -0.33, p = 0.0039). ADC values (± SD) of low-grade meningiomas (0.84 ± 0.14 × 10(-3) mm(2)/s) and aggressive (atypical or anaplastic) meningiomas (0.75 ± 0.03 × 10(-3) mm(2)/s) were significantly different (p = 0.0495). Using an ADC cutoff value of 0.70 × 10(-3) mm(2)/s, the sensitivity for diagnosing aggressive meningiomas was 29%, specificity was 94%, positive predictive value was 67%, and negative predictive value was 75%. ADC values correlate inversely with Ki-67 proliferation index and help differentiate low-grade from aggressive meningiomas.

  1. Expression of geminin, p16, and Ki67 in cervical intraepithelial neoplasm and normal tissues.

    Science.gov (United States)

    Xing, Yan; Wang, Chaojun; Wu, Jie

    2017-06-01

    Geminin is a protein involved in cell cycle progression. We aimed to evaluate the diagnostic value of geminin expression in cervical intraepithelial neoplasm (CIN).The expression of geminin, p16, and Ki67 was examined in 95 samples, including CIN1 (n = 45), CIN2/3 (n = 40), and normal cervical tissues (n = 10) by immunohistochemistry. The correlation between geminin or p16 expression and human papillomavirus (HPV) status was also evaluated.Geminin expression was negative in all normal tissues and expressed in 13.3% of CIN1 and 90.0% of CIN2/3. P16 expression was demonstrated in 24.4% of CIN1 and 87.5% of CIN2/3. The corresponding Ki67 expression was 35.6% and 95.0%. The specificity of geminin for differentiating between CIN1 and CIN2/3 was 86.7%, while for p16 and Ki67 the corresponding values were 75.6% and 64.4%. The sensitivity of geminin, p16, and Ki67 was 90.0%, 87.5%, and 95.0%, respectively. The positive predictive value (PPV) and accuracy of geminin were higher than p16 and Ki67. In addition, geminin expression showed a weak correlation with HPV status, but there was no association between p16 expression and HPV status.These results suggested that geminin had a high degree of sensitivity and specificity in determining CIN2/3. In addition to p16 and Ki67, geminin might be used as a new biomarker to distinguish between CIN1 and CIN2/3.

  2. Effects of the KiVa antibullying program on cyberbullying and cybervictimization frequency among Finnish youth.

    Science.gov (United States)

    Williford, Anne; Elledge, L Christian; Boulton, Aaron J; DePaolis, Kathryn J; Little, Todd D; Salmivalli, Christina

    2013-01-01

    Cyberbullying among school-aged children has received increased attention in recent literature. However, no empirical evidence currently exists on whether existing school-based antibullying programs are effective in targeting the unique aspects of cyberbullying. To address this important gap, the present study investigates the unique effects of the KiVa Antibullying Program on the frequency of cyberbullying and cybervictimization among elementary and middle school youth. Using data from a group randomized controlled trial, multilevel ordinal regression analyses were used to examine differences in the frequencies of cyberbullying and cybervictimization between intervention (N = 9,914) and control students (N = 8,498). The effects of age and gender on frequencies of cyber behaviors were also assessed across conditions. Results revealed a significant intervention effect on the frequency of cybervictimization; KiVa students reported lower frequencies of cybervictimization at posttest than students in a control condition. The effect of condition on the perpetration of cyberbullying was moderated by age. When student age was below the sample mean, KiVa students reported lower frequencies of cyberbullying than students in the control condition. We also found evidence of classroom level variation in cyberbullying and cybervictimization, suggesting cyberbullying is in part a classroom-level phenomenon. KiVa appears to be an efficacious program to address cyber forms of bullying and victimization. We discuss several unique aspects of KiVa that may account for the significant intervention effects. Results suggest that KiVa is an intervention option for schools concerned with reducing cyberbullying behavior and its deleterious effects on children's adjustment.

  3. Expression of Progestrone Receptor and Proliferative Marker ki 67, in Various Grades of Meningioma

    Directory of Open Access Journals (Sweden)

    Nasrin Shayanfar

    2010-05-01

    Full Text Available Meningiomas are slow-growing neoplasms which recur locally, their morphologic grading is simple but do not always correlate with patient outcome. The aim of present study is to evaluate the status of progesterone receptor (PR and proliferation marker Ki67 in various grades of meningioma in a group of Iranian patients. 78 cases of meningioma were selected from the file of a hospital university. All archival H&E stained sections were reviewed and regraded according to WHO criteria. Immunohistochemical analysis for PR and Ki67 was performed on formalin- fixed, paraffin- embedded samples. PR status considered positive if > 10% of tumor cell's nuclei were strongly immunoreactive, or if > 50% of nuclei were stained with medium intensity. The Ki67 labeling index (LI is defined as the percentage area with strongest immunostaining. PR were positive in 61/63(96.8% of grade I tumors,2/10(20% of grade II,and 0/5(0% of grade III tumors.Ki67 LI was %2.98±2.27 in grade I tumors, %9.30±5.79 in grade II tumors and %34.00±5.47 in grade III tumors. For both markers, differences between grade I,II and III tumors were significant(P<0.001.There was a reverse relationship between mean of Ki67 LI and PR status,with increasing grade of tumor. Evaluation of PR status and Ki67 LI together with conventional histologic evaluation can help in providing more information about the biologic behaviour of meningiomas,especially for those that histological grading is not straightforward.

  4. An evaporation model of multicomponent solution drops

    Science.gov (United States)

    Sartori, Silvana; Liñán, Amable; Lasheras, Juan C.

    2010-11-01

    Solutions of polymers are widely used in the pharmaceutical industry as tablets coatings. These allow controlling the rate at which the drug is delivered, taste or appearance. The coating is performed by spraying and drying the tablets at moderate temperatures. The wetting of the coating solution on the pill's surface depends on the droplet Webber and Re numbers, angle of impact and on the rheological properties of the droplet. We present a model for the evaporation of multicomponent solutions droplets in a hot air environment with temperatures substantially lower than the boiling temperature of the solvent. As the liquid vaporizes from the surface the fluid in the drop increases in concentration, until reaching its saturation point. After saturation, precipitation occurs uniformly within the drop. As the surface regresses, a compacting front formed by the precipitate at its maximum packing density advances into the drop, while the solute continues precipitating uniformly. This porous shell grows fast due to the double effect of surface regression and precipitation. The evaporation rate is determined by the rates at which heat is transported to the droplet surface and at which liquid vapor diffuses away from it. When the drop is fully compacted, the evaporation is drastically reduced.

  5. An evaporation model of colloidal suspension droplets

    Science.gov (United States)

    Sartori, Silvana; Li\\ Nán, Amable; Lasheras, Juan C.

    2009-11-01

    Colloidal suspensions of polymers in water or other solvents are widely used in the pharmaceutical industry to coat tablets with different agents. These allow controlling the rate at which the drug is delivered, taste or physical appearance. The coating is performed by simultaneously spraying and drying the tablets with the colloidal suspension at moderately high temperatures. The spreading of the coating on the pills surface depends on the droplet Webber and Reynolds numbers, angle of impact, but more importantly on the rheological properties of the drop. We present a model for the evaporation of a colloidal suspension droplet in a hot air environment with temperatures substantially lower than the boiling temperature of the carrier fluid. As the liquid vaporizes from the surface, a compacting front advances into the droplet faster than the liquid surface regresses, forming a shell of a porous medium where the particles reach their maximum packing density. While the surface regresses, the evaporation rate is determined by both the rate at which heat is transported to the droplet surface and the rate at which liquid vapor is diffused away from it. This regime continues until the compacting front reaches the center of the droplet, at which point the evaporation rate is drastically reduced.

  6. Quantifying Evaporation in a Permeable Pavement System ...

    Science.gov (United States)

    Studies quantifying evaporation from permeable pavement systems are limited to a few laboratory studies and one field application. This research quantifies evaporation for a larger-scale field application by measuring the water balance from lined permeable pavement sections. The U.S. Environmental Protection Agency (USEPA) constructed a 0.4-ha parking lot in Edison, NJ, that incorporated three different permeable pavement types in the parking lanes – permeable interlocking concrete pavers (PICP), pervious concrete (PC), and porous asphalt (PA). An impermeable liner installed 0.4 m below the driving surface in four 11.6-m by 4.74-m sections per each pavement type captures all infiltrating water and routes it to collection tanks that can contain events up to 38 mm. Each section has a design impervious area to permeable pavement area ratio of 0.66:1. Pressure transducers installed in the underdrain collection tanks measured water level for 24 months. Level was converted to volume using depth-to-volume ratios for individual collection tanks. Using a water balance approach, the measured infiltrate volume was compared to rainfall volume on an event-basis to determine the rainfall retained in the pavement strata and underlying aggregate. Evaporation since the previous event created additional storage in the pavement and aggregate layers. Events were divided into three groups based on antecedent dry period (ADP) and three, four-month categories of potential e

  7. SCC of stainless steel under evaporative conditions

    Energy Technology Data Exchange (ETDEWEB)

    Andersen, H.; Arnvig, P.E.; Wasielewska, W.; Wegrelius, L.; Wolfe, C. [Avesta Sheffield AB, Avesta (Sweden)

    1998-12-31

    Three different test methods have been used to assess the susceptibility of different stainless steel grades to SCC under evaporative and immersed conditions. The methods employed were the drop evaporation test, the wick test and a high temperature, high pressure test simulating a feedwater heater tubing application in power plants. The alloys investigated were commercially produced austenitic and duplex stainless steels varying in chemical composition, plus one copper-nickel alloy. The resistance of austenitic stainless steels towards SCC increased by increasing the content of Ni, Mo and Cr, thus the super austenitic 654SMO{reg_sign} (uns32654) did not show any cracking in any of the three tests. The super austenitic 254SMO{reg_sign} (UNS31254) revealed only slight SCC in the simulated feed water heater tubing application while the equivalent N08367 revealed severe pitting and cracking. The drop evaporation test exhibited the most severe test conditions characterized by thermally induced fatigue effects, sensibility to onset of corrosion and severe acidic conditions generated under deposits on the test specimen. Some factors in stress corrosion cracking tests such as thermal fatigue, diffusion, heat transfer and stress condition, are discussed with regard to their influence on the test results.

  8. Spin coating of an evaporating polymer solution

    KAUST Repository

    Münch, Andreas

    2011-01-01

    We consider a mathematical model of spin coating of a single polymer blended in a solvent. The model describes the one-dimensional development of a thin layer of the mixture as the layer thins due to flow created by a balance of viscous forces and centrifugal forces and evaporation of the solvent. In the model both the diffusivity of the solvent in the polymer and the viscosity of the mixture are very rapidly varying functions of the solvent mass fraction. Guided by numerical solutions an asymptotic analysis reveals a number of different possible behaviours of the thinning layer dependent on the nondimensional parameters describing the system. The main practical interest is in controlling the appearance and development of a "skin" on the polymer where the solvent concentration reduces rapidly on the outer surface leaving the bulk of the layer still with high concentrations of solvent. In practice, a fast and uniform drying of the film is required. The critical parameters controlling this behaviour are found to be the ratio of the diffusion to advection time scales ε, the ratio of the evaporation to advection time scales δ and the ratio of the diffusivity of the pure polymer and the initial mixture exp(-1/γ). In particular, our analysis shows that for very small evaporation with δ

  9. Metastability of a-SiO{sub x}:H thin films for c-Si surface passivation

    Energy Technology Data Exchange (ETDEWEB)

    Serenelli, L., E-mail: luca.serenelli@enea.it [ENEA Research centre “Casaccia”, via Anguillarese 301, 00123 Rome (Italy); DIET University of Rome “Sapienza”, via Eudossiana 18, 00184 Rome (Italy); Martini, L. [DIET University of Rome “Sapienza”, via Eudossiana 18, 00184 Rome (Italy); Imbimbo, L. [ENEA Research centre “Casaccia”, via Anguillarese 301, 00123 Rome (Italy); DIET University of Rome “Sapienza”, via Eudossiana 18, 00184 Rome (Italy); Asquini, R. [DIET University of Rome “Sapienza”, via Eudossiana 18, 00184 Rome (Italy); Menchini, F.; Izzi, M.; Tucci, M. [ENEA Research centre “Casaccia”, via Anguillarese 301, 00123 Rome (Italy)

    2017-01-15

    Highlights: • a-SiO{sub x}:H film deposition by RF-PECVD is optimized from SiH{sub 4}, CO{sub 2} and H{sub 2} gas mixture. • Metastability of a-SiO{sub x}:H/c-Si passivation is investigated under thermal annealing and UV exposure. • A correlation between passivation metastability and Si−H bonds is found by FTIR spectra. • A metastability model is proposed. - Abstract: The adoption of a-SiO{sub x}:H films obtained by PECVD in heterojunction solar cells is a key to further increase their efficiency, because of its transparency in the UV with respect to the commonly used a-Si:H. At the same time this layer must guarantee high surface passivation of the c-Si to be suitable in high efficiency solar cell manufacturing. On the other hand the application of amorphous materials like a-Si:H and SiN{sub x} on the cell frontside expose them to the mostly energetic part of the sun spectrum, leading to a metastability of their passivation properties. Moreover as for amorphous silicon, thermal annealing procedures are considered as valuable steps to enhance and stabilize thin film properties, when performed at opportune temperature. In this work we explored the reliability of a-SiO{sub x}:H thin film layers surface passivation on c-Si substrates under UV exposition, in combination with thermal annealing steps. Both p- and n-type doped c-Si substrates were considered. To understand the effect of UV light soaking we monitored the minority carriers lifetime and Si−H and Si−O bonding, by FTIR spectra, after different exposure times to light coming from a deuterium lamp, filtered to UV-A region, and focused on the sample to obtain a power density of 50 μW/cm{sup 2}. We found a certain lifetime decrease after UV light soaking in both p- and n-type c-Si passivated wafers according to a a-SiO{sub x}:H/c-Si/a-SiO{sub x}:H structure. The role of a thermal annealing, which usually enhances the as-deposited SiO{sub x} passivation properties, was furthermore considered. In

  10. Kovačičevi etiški pogledi

    OpenAIRE

    Žalec, Bojan

    2015-01-01

    Članek predstavi etiško misel Frana Kovačiča. Kovačič je zagovarjal heteronomno etiko, ki je utemeljena na absolutni ali božanski stvarnosti. Pojasnjeval je, da so bili njeni predstavniki tudi Sokrat, Platon in Aristotel. Kovačič je zavračal zamisel absolutnega napredka kot (etične) vrednote. Kriza sodobne etike po njegovem mnenju izvira iz zamisli o avtonomnosti etike, iz subjektivizma, skepticizma, scientizma in naturalizma, ki se različno kombinirajo v raznih a(nti)teističnih etiških pogle...

  11. KONCIPIRANJE IN ZASNOVA STIRLINGOVEGA MOTORJA, KI BO IZRABLJAL POTENCIAL DIMNIH PLINOV IZ PEČI

    OpenAIRE

    Fürst, Matej

    2011-01-01

    V svoji diplomski nalogi sem se posvetil koncipiranju naprave, ki izkorišča vroče pline iz peči v gospodinjstvu in proizvaja električno energijo. Princip bi bil pretvarjanje toplote v električno energijo. Posvetil sem se različnim modelom Stirlingovega motorja in generatorja, ter raziskal njihove prednosti in slabosti. Osredotočil sem se tudi na nekatere energente in temperature zgorevanja. Na koncu sem pretehtal rezultate in na podlagi prednosti in slabosti izbral rešitev, ki je bila najbolj...

  12. Association of tissue inhibitor of metalloproteinases-1 and Ki67 in estrogen receptor positive breast cancer

    DEFF Research Database (Denmark)

    Bjerre, Christina Annette; Knoop, Ann; Bjerre, Karsten

    2013-01-01

    The role of tissue inhibitor of metalloproteinases-1 (TIMP-1) in estrogen receptor (ER) positive breast cancer remains to be fully elucidated. We evaluated TIMP-1 as a prognostic marker in patients treated with adjuvant tamoxifen and investigated TIMP-1s association with Ki67 and ER/progesterone ....../progesterone receptor (PR)/human epidermal growth factor receptor 2 (HER2) profiles.......The role of tissue inhibitor of metalloproteinases-1 (TIMP-1) in estrogen receptor (ER) positive breast cancer remains to be fully elucidated. We evaluated TIMP-1 as a prognostic marker in patients treated with adjuvant tamoxifen and investigated TIMP-1s association with Ki67 and ER...

  13. Free-volume defects investigation of GeS2-Ga2S3-CsI chalcogenide glasses by positron annihilation spectroscopy

    Science.gov (United States)

    Li, Junpeng; Wang, Guoxiang; Lin, Changgui; Zhang, Tengyu; Zhang, Rui; Huang, Zhaohuang; Shen, Xiang; Gu, Bingchuan; Ye, Bangjiao; Ying, Feifei; Li, Maozhong; Nie, Qiuhua

    2017-06-01

    The transformation behavior of free-volume defect in (80GeS2-20Ga2S3)100-x (CsI)x (x = 0, 5, 10, 15 mol%) chalcogenide glasses was studied by employing positron annihilation spectroscopic technique, which could reveal valuable information for in-depth understanding of nano-structural defects in glassy matrix. The results indicate that the structural changes caused by CsI additives can be adequately described by positron trapping modes determined with two-state model. The initial addition of CsI (x = 5 mol%) led to a void contraction, whereas, the void agglomeration occurred with the increase of CsI and the free-volume defects of the glasses were obviously reduced. The atomic density ρ is inversely proportional to the number of these defects. Meanwhile, the UV cut-off edge shifts toward short-wavelength with increasing of CsI. This study provides the valuable information of defects evolution in GeS2-Ga2S3-CsI glasses.

  14. Developmental and hormonally regulated messenger ribonucleic acid expression of KiSS-1 and its putative receptor, GPR54, in rat hypothalamus and potent luteinizing hormone-releasing activity of KiSS-1 peptide.

    Science.gov (United States)

    Navarro, V M; Castellano, J M; Fernández-Fernández, R; Barreiro, M L; Roa, J; Sanchez-Criado, J E; Aguilar, E; Dieguez, C; Pinilla, L; Tena-Sempere, M

    2004-10-01

    The gonadotropic axis is centrally controlled by a complex regulatory network of excitatory and inhibitory signals that is activated at puberty. Recently, loss of function mutations of the gene encoding G protein-coupled receptor 54 (GPR54), the putative receptor for the KiSS-1-derived peptide metastin, have been associated with lack of puberty onset and hypogonadotropic hypogonadism. Yet the pattern of expression and functional role of the KiSS-1/GPR54 system in the rat hypothalamus remain unexplored to date. In the present work, expression analyses of KiSS-1 and GPR54 genes were conducted in different physiological and experimental settings, and the effects of central administration of KiSS-1 peptide on LH release were assessed in vivo. Persistent expression of KiSS-1 and GPR54 mRNAs was detected in rat hypothalamus throughout postnatal development, with maximum expression levels at puberty in both male and female rats. Hypothalamic expression of KiSS-1 and GPR54 genes changed throughout the estrous cycle and was significantly increased after gonadectomy, a rise that was prevented by sex steroid replacement both in males and females. Moreover, hypothalamic expression of the KiSS-1 gene was sensitive to neonatal imprinting by estrogen. From a functional standpoint, intracerebroventricular administration of KiSS-1 peptide induced a dramatic increase in serum LH levels in prepubertal male and female rats as well as in adult animals. In conclusion, we provide novel evidence of the developmental and hormonally regulated expression of KiSS-1 and GPR54 mRNAs in rat hypothalamus and the ability of KiSS-1 peptide to potently stimulate LH secretion in vivo. Our current data support the contention that the hypothalamic KiSS-1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood.

  15. Dosimetric comparison between proton and photon beams in the moving gap region in cranio-spinal irradiation (CSI).

    Science.gov (United States)

    Cheng, Chee-Wai; Das, Indra J; Srivastava, Shiv P; Zhao, Li; Wolanski, Mark; Simmons, Joseph; Johnstone, Peter A S; Buchsbaum, Jeffrey C

    2013-04-01

    To investigate the moving gap region dosimetry in proton beam cranio-spinal irradiation (CSI) to provide optimal dose uniformity across the treatment volume. Proton beams of ranges 11.6 cm and 16 cm are used for the spine and the brain fields, respectively. Beam profiles for a 30 cm snout are first matched at the 50% level (hot match) on the computer. Feathering is simulated by shifting the dose profiles by a known distance two successive times to simulate a 2 × feathering scheme. The process is repeated for 2 mm and 4 mm gaps. Similar procedures are used to determine the dose profiles in the moving gap for a series of gap widths, 0-10 mm, and feathering step sizes, 4-10 mm, for a Varian iX 6MV beam. The proton and photon dose profiles in the moving gap region are compared. The dose profiles in the moving gap exhibit valleys and peaks in both proton and photon beam CSI. The dose in the moving gap for protons is around 100% or higher for 0 mm gap, for both 5 and 10 mm feathering step sizes. When the field gap is comparable or larger than the penumbra, dose minima as low as 66% is obtained. The dosimetric characteristics for 6 MV photon beams can be made similar to those of the protons by appropriately combining gap width and feathering step size. The dose in the moving gap region is determined by the lateral penumbras, the width of the gap and the feathering step size. The dose decreases with increasing gap width or decreasing feathering step size. The dosimetric characteristics are similar for photon and proton beams. However, proton CSI has virtually no exit dose and is beneficial for pediatric patients, whereas with photon beams the whole lung and abdomen receive non-negligible exit dose.

  16. Transfer and breakup reactions in 16O + CsI at 16.4 MeV/n

    Directory of Open Access Journals (Sweden)

    M.J. Murphy

    1983-01-01

    Full Text Available A streamer-chamber particle-telescope system has been used to observe ejectile charge, energy, and associated charged particle multiplicity in the reaction of 16O + CsI at 16.4 MeV/n. The measurement provides relative probabilities for transfer and projectile breakup as a function of ejectile charge, and spectra for the heavy ejectiles from transfer and breakup events. The results show that the interaction energy of 16.4 MeV/n is near the threshold for breakup reactions in heavy-ion collisions.

  17. Surface passivation of c-Si for silicon heterojunction solar cells using high-pressure hydrogen diluted plasmas

    Directory of Open Access Journals (Sweden)

    Dimitrios Deligiannis

    2015-09-01

    Full Text Available In this work we demonstrate excellent c-Si surface passivation by depositing a-Si:H in the high-pressure and high hydrogen dilution regime. By using high hydrogen dilution of the precursor gases during deposition the hydrogen content of the layers is sufficiently increased, while the void fraction is reduced, resulting in dense material. Results show a strong dependence of the lifetime on the substrate temperature and a weaker dependence on the hydrogen dilution. After applying a post-deposition annealing step on the samples equilibration of the lifetime occurs independent of the initial nanostructure.

  18. Microsolvation of LiI and CsI in water: anion photoelectron spectroscopy and ab initio calculations.

    Science.gov (United States)

    Li, Ren-Zhong; Liu, Cheng-Wen; Gao, Yi Qin; Jiang, Hong; Xu, Hong-Guang; Zheng, Wei-Jun

    2013-04-03

    In order to understand the microsolvation of LiI and CsI in water and provide information about the dependence of solvation processes on different ions, we investigated the LiI(H2O)n(-) and CsI(H2O)n(-) (n = 0-6) clusters using photoelectron spectroscopy. The structures of these clusters and their corresponding neutrals were investigated with ab initio calculations and confirmed by comparing with the photoelectron spectroscopy experiments. Our studies show that the structural evolutions of LiI(H2O)n and CsI(H2O)n clusters are very different. The Li-I distance in LiI(H2O)n(-) increases abruptly at n = 3, whereas the abrupt elongation of the Li-I distance in neutral LiI(H2O)n occurs at n = 5. In contrast to the LiI(H2O)n(-) clusters, the Cs-I distance in CsI(H2O)n(-) increases significantly at n = 3, reaches a maximum at n = 4, and decreases again as n increases further. There is no abrupt change of the Cs-I distance in neutral CsI(H2O)n as n increases from 0 to 6. Water molecules interact strongly with the Li ion; consequently, water molecule(s) can insert within the Li(+)-I(-) ion pair. In contrast, five or six water molecules are not enough to induce obvious separation of the Cs(+)-I(-) ion pair since the Cs-water interaction is relatively weak compared to the Li-water interaction. Our work has shown that the structural variation and microsolvation in MI(H2O)n clusters are determined by the delicate balance between ion-ion, ion-water, and water-water interactions, which may have significant implications for the general understanding of salt effects in water solution.

  19. Centers of near-IR luminescence in bismuth-doped TlCl and CsI crystals.

    Science.gov (United States)

    Sokolov, V O; Plotnichenko, V G; Dianov, E M

    2013-04-22

    A comparative first-principles study of possible bismuth-related centers in TlCl and CsI crystals is performed and the results of computer modeling are compared with the experimental data. The calculated spectral properties of the bismuth centers suggest that the IR luminescence in TlCl:Bi is most likely caused by Bi(+)···V(Cl)(-) centers (Bi(+) ion in thallium site and a negatively charged chlorine vacancy in the nearest anion site). On the contrary, Bi(+) substitutional ions and Bi(2)(+) dimers are most likely responsible for the IR luminescence in CsI:Bi.

  20. Evaporation-triggered microdroplet nucleation and the four life phases of an evaporating Ouzo drop

    Science.gov (United States)

    Tan, Huanshu; Diddens, Christian; Lv, Pengyu; Kuerten, J. G. M.; Zhang, Xuehua; Lohse, Detlef

    2016-11-01

    Evaporating liquid droplets are omnipresent in nature and technology, such as in inkjet printing, coating, deposition of materials, medical diagnostics, agriculture, the food industry, cosmetics, or spills of liquids. Here we show that the evaporation of such ternary mixtures can trigger a phase transition and the nucleation of microdroplets of one of the components of the mixture. As a model system, we pick a sessile Ouzo droplet (as known from daily life) and reveal and theoretically explain its four life phases: In phase I, the spherical cap-shaped droplet remains transparent while the more volatile ethanol is evaporating, preferentially at the rim of the drop because of the singularity there. This leads to a local ethanol concentration reduction and correspondingly to oil droplet nucleation there. This is the beginning of phase II, in which oil microdroplets quickly nucleate in the whole drop, leading to its milky color that typifies the so-called "Ouzo effect." Once all ethanol has evaporated, the drop, which now has a characteristic nonspherical cap shape, has become clear again, with a water drop sitting on an oil ring (phase III), finalizing the phase inversion. Finally, in phase IV, all water has evaporated, leaving behind a tiny spherical cap-shaped oil drop.

  1. Evaporation Kinetics of Polyol Droplets: Determination of Evaporation Coefficients and Diffusion Constants

    Science.gov (United States)

    Su, Yong-Yang; Marsh, Aleksandra; Haddrell, Allen E.; Li, Zhi-Ming; Reid, Jonathan P.

    2017-11-01

    In order to quantify the kinetics of mass transfer between the gas and condensed phases in aerosol, physicochemical properties of the gas and condensed phases and kinetic parameters (mass/thermal accommodation coefficients) are crucial for estimating mass fluxes over a wide size range from the free molecule to continuum regimes. In this study, we report measurements of the evaporation kinetics of droplets of 1-butanol, ethylene glycol (EG), diethylene glycol (DEG), and glycerol under well-controlled conditions (gas flow rates and temperature) using the previously developed cylindrical electrode electrodynamic balance technique. Measurements are compared with a model that captures the heat and mass transfer occurring at the evaporating droplet surface. The aim of these measurements is to clarify the discrepancy in the reported values of mass accommodation coefficient (αM, equals to evaporation coefficient based on microscopic reversibility) for 1-butanol, EG, and DEG and improve the accuracy of the value of the diffusion coefficient for glycerol in gaseous nitrogen. The uncertainties in the thermophysical and experimental parameters are carefully assessed, the literature values of the vapor pressures of these components are evaluated, and the plausible ranges of the evaporation coefficients for 1-butanol, EG, and DEG as well as uncertainty in diffusion coefficient for glycerol are reported. Results show that αM should be greater than 0.4, 0.2, and 0.4 for EG, DEG, and 1-butanol, respectively. The refined values are helpful for accurate prediction of the evaporation/condensation rates.

  2. Clinicopathological and Prognostic Value of Ki-67 Expression in Bladder Cancer: A Systematic Review and Meta-Analysis.

    Directory of Open Access Journals (Sweden)

    Yuejun Tian

    Full Text Available Ki-67 is an established marker of cell proliferation, and the Ki-67 index correlates with the clinical course of several cancer types, including bladder cancer (BC. However, the clinicopathological and prognostic significance of Ki-67 in bladder cancer remains unclear. Therefore, we performed a systematic review and meta-analysis to clarify this relationship.A comprehensive literature search for relevant studies published up to February 1, 2016, was performed using PubMed, Cochrane Library, Embase and ISI Web of Knowledge. The effects of Ki-67 expression on survival outcome in patients with BC and BC subtypes were evaluated. Furthermore, the relationship between Ki-67 expression and the clinicopathological features of BC were assessed.Thirty-one studies with 5147 bladder cancer patients were selected for evaluation. Ki-67 expression was significantly associated with shorter recurrence-free (HR 1.69, 95% CI: 1.33-2.14, progression-free (HR 1.89, 95% CI: 1.43-2.51, overall (HR 2.03, 95% CI: 1.31-3.16, and cancer-specific (HR 1.69, 95% CI: 1.47-1.95 survival. Moreover, whereas high expression was more common in high tumor stage, recurrence status, tumor size, there was no correlation between high Ki-67 expression and age, gender, smoking habits, and tumor number. Importantly, analysis of the different subgroups of BC suggested that significant correlations between high Ki-67 expression and survival outcome (recurrence-free/progression-free/overall/cancer-specific survival are present only in European-American patients.The present results indicate that over-expression of Ki-67 is distinctly correlated with poor patient survival. Ki-67 may serve as a valuable biomarker for prognosis in BC patients, particularly in non-Asian BC patients. The results suggest no significant association between Ki-67 expression and BC prognosis in Asian patients. Further efforts are needed to fully clarify this relationship.

  3. DISCOVERY OF SiCSi IN IRC+10216: A MISSING LINK BETWEEN GAS AND DUST CARRIERS OF Si–C BONDS

    Energy Technology Data Exchange (ETDEWEB)

    Cernicharo, J.; Agúndez, M.; Prieto, L. Velilla; Quintana-Lacaci, G. [Group of Molecular Astrophysics, ICMM, CSIC, C/Sor Juana Inés de La Cruz N3, E-28049, Madrid (Spain); McCarthy, M. C.; Gottlieb, C. A.; Drumel, M. A. Martin-; Patel, N. A.; Reilly, N. J.; Young, K. H. [Harvard-Smithsonian Center for Astrophysics, Cambridge, MA 02138, and School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138 (United States); Baraban, J. H. [Department of Chemistry and Biochemistry, University of Colorado, Boulder, CO 80309 (United States); Changala, P. B. [JILA, National Institute of Standards and Technology and University of Colorado, and Department of Physics, University of Colorado, Boulder, CO 80309 (United States); Guélin, M. [Institut de Radioastronomie Millimétrique, 300 rue de la Piscine, F-38406 St-Martin d’Hères (France); Kahane, C. [Universit Grenoble Alpes, IPAG, F-38000 Grenoble (France); CNRS, IPAG, F-38000 Grenoble (France); Stanton, J. F. [Institute for Theoretical Chemistry, Department of Chemistry, The University of Texas at Austin, Austin, TX 78712 (United States); Thorwirth, S. [I. Physikalisches Institut, Universität zu Köln, Zülpicher Str. 77, D-50937 Köln (Germany)

    2015-06-10

    We report the discovery in space of a disilicon species, SiCSi, from observations between 80 and 350 GHz with the IRAM 30 m radio telescope. Owing to the close coordination between laboratory experiments and astrophysics, 112 lines have now been detected in the carbon-rich star CW Leo. The derived frequencies yield improved rotational and centrifugal distortion constants up to sixth order. From the line profiles and interferometric maps with the Submillimeter Array, the bulk of the SiCSi emission arises from a region of 6″ in radius. The derived abundance is comparable to that of SiC{sub 2}. As expected from chemical equilibrium calculations, SiCSi and SiC{sub 2} are the most abundant species harboring a Si−C bond in the dust formation zone and certainly both play a key role in the formation of SiC dust grains.

  4. Avafestivalile andis värvi Aki Kaurismäki / Tiit Tuumalu

    Index Scriptorium Estoniae

    Tuumalu, Tiit, 1971-

    2011-01-01

    Tallinna Pimedate Ööde esimesest Filmifestivalist. PÖFF'i juhi Tiina Loki, Kanal 2 programmidirektori Olle Mirme, PÖFFI pressijuhi Helmut Jänese, režissööri ja produtsendi Jaak Kilmi ning 1997 aasta PÖFF'i külalise soome filmirežissööri Aki Kaurismäki arvamus

  5. Vitamin D Receptor, Retinoid X Receptor, Ki-67, Survivin, and Ezrin Expression in Canine Osteosarcoma

    Directory of Open Access Journals (Sweden)

    John Davies

    2012-01-01

    Full Text Available Canine osteosarcoma (OS is an aggressive malignant bone tumor. Prognosis is primarily determined by clinical parameters. Vitamin D has been postulated as a novel therapeutic option for many malignancies. Upon activation, vitamin D receptors (VDRs combine with retinoid receptor (RXR forming a heterodimer initiating a cascade of events. Vitamin D's antineoplastic activity and its mechanism of action in OS remain to be clearly established. Expression of VDR, RXR, Ki-67, survivin, and ezrin was studied in 33 archived, canine OS specimens. VDR, RXR, survivin, and ezrin were expressed in the majority of cases. There was no statistically significant difference in VDR expression in relationship with tumor grade, type, or locations or animal breed, age, and/or sex. No significant association (p=0.316 between tumor grade and Ki-67 expression was found; in particular, no difference in Ki-67 expression between grades 2 and 3 OSs was found, while a negative correlation was noted between Ki-67 and VDR expression (ρ=−0.466, a positive correlation between survivin and RXR expression was found (p=0.374. A significant relationship exists between VDR and RXR expression in OSs and proliferative/apoptosis markers. These results establish a foundation for elucidating mechanisms by which vitamin D induces antineoplastic activity in OS.

  6. Analysis of the Ki-67 index in the vaginal epithelium of castrated rats treated with tamoxifen

    Directory of Open Access Journals (Sweden)

    Afif Rieth Nery-Aguiar

    2016-02-01

    Full Text Available OBJECTIVES: Vaginal atrophy and breast cancer are common conditions in postmenopausal women and tamoxifen is the standard endocrine treatment for hormone-sensitive tumors. The present study aimed to assess the effect of tamoxifen on Ki-67 protein expression in the vaginal epithelium of castrated rats. MATERIAL AND METHODS: Forty Wistar-Hannover adult, virgin, castrated rats were randomly divided into two groups, group I (control, n=20 and group II (tamoxifen, n=20, receiving 0.5 ml of propylene glycol and 250 µg of tamoxifen diluted in 0.5 ml of propylene glycol, respectively, daily by gavage for 30 days. On the 31st day, the rats were euthanized and their vaginas were removed and fixed in 10% buffered formalin for the immunohistochemical study of Ki-67 protein expression. Data were analyzed by the Levene and Student’s t tests (p<0.05. RESULTS: The mean index of Ki-67 expression in the rat vagina of groups I and II was 4.04±0.96 and 26.86±2.19, respectively (p<0.001. CONCLUSIONS: According to the results of the present study, tamoxifen, at the dose and treatment length used, induced a significant increase in the cell proliferation of the vaginal mucosa in castrated rats, as evaluated by Ki-67 protein expression.

  7. Implementing the KiVa Antibullying Program: Recognition of Stable Victims

    Science.gov (United States)

    Haataja, Anne; Sainio, Miia; Turtonen, Mira; Salmivalli, Christina

    2016-01-01

    Teachers do not always recognise students who are victimised by their peers. In this study, we examined the recognition of stable victims in 76 schools beginning to implement the KiVa antibullying programme. We focused on 348 victims (9-15 years) who reported victimisation at the pretest and still at wave 2, after five months of programme…

  8. A KiDS weak lensing analysis of assembly bias in GAMA galaxy groups

    NARCIS (Netherlands)

    Dvornik, Andrej; Cacciato, Marcello; Kuijken, Konrad; Viola, Massimo; Hoekstra, Henk; Nakajima, Reiko; van Uitert, Edo; Brouwer, Margot; Choi, Ami; Erben, Thomas; Fenech Conti, Ian; Farrow, Daniel J.; Herbonnet, Ricardo; Heymans, Catherine; Hildebrandt, Hendrik; Hopkins, Andrew. M.; McFarland, John; Norberg, Peder; Schneider, Peter; Sifón, Cristóbal; Valentijn, Edwin; Wang, Lingyu

    2017-01-01

    We investigate possible signatures of halo assembly bias for spectroscopically selected galaxy groups from the GAMA survey using weak lensing measurements from the spatially overlapping regions of the deeper, high-imaging-quality photometric KiDS survey. We use GAMA groups with an apparent richness

  9. Translation, cultural adaptation and validation of the Kidney Disease Knowledge Survey (KiKS) to Spanish

    Science.gov (United States)

    Mota-Anaya, Evelin; Yumpo-Cárdenas, Daniel; Alva-Bravo, Edmundo; Wright Nunes, Julie A.; Mayta-Tristán, Percy

    2016-01-01

    Introduction Chronic kidney disease (CKD) affects 50 million people globally. Several studies show the importance of implementing interventions that enhance patients' knowledge about their disease. In 2011, the Kidney Disease Knowledge Survey (KiKS) was developed, a questionnaire that assesses the specific knowledge about CKD in pre-dialysis patients. Objective To translate to Spanish, culturally adapt and validate the questionnaire KiKS in a population of patients with pre-dialysis CKD. Methods The translation and cultural adaptation of KiKS was performed. Subsequently, its validity and reliability were determined. The validity was evaluated by construct validity; and the reliability by its internal consistency and its intra-observer reliability (test-retest). Results A good internal consistency was found (Kuder-Richardson = 0.85). Regarding intra-observer reliability, the intraclass correlation coefficient with a value of 0.78 (95% CI: 0.5–1.0) indicated a good reproducibility; the mean difference of −1.1 test-retest S.D. 6.0 (p = 0.369) confirm this. Conclusions The Spanish version of KiKS is acceptable and equivalent to the original version and has good reliability, validity and reproducibility. Therefore, it could be used in a population of culturally similar patients with pre-dialysis CKD. PMID:27513762

  10. Analysis on the relation of pterygium with VEGF,SDF-1,Ki-67,PCNA and Survivin

    Directory of Open Access Journals (Sweden)

    Ying Song

    2015-12-01

    Full Text Available AIM:To analyze and study the relation of pterygium with vascular endothelial growth factor(VEGF,stroma cell-derived factor 1(SDF-1,tumor proliferating antigen(Ki-67,proliferating cell nuclear antigen(PCNAand survivin. METHODS:Seventy-nine patients(106 eyeswith pterygium from January 2013 to May 2015 in our hospital were selected as observation group. Seventy-nine persons with normal conjunctiva during the same period were selected as control group. Then the number of positive cells and staining intensity classification of the two groups for VEGF,SDF-1,Ki-67,PCNA and survivin were compared,and the detection results of patients with different gender,stages and types were compared too. Then the relation between pterygium and those indexes were analyzed by the Logistic analysis. RESULTS:The number of positive cells and staining intensity classification of observation group for VEGF,SDF-1,Ki-67,PCNA and survivin were all higher than those of control group,and the detection results of patients with different stages and types had certain differences too(all PP>0.05. All those indexes had close relation to pterygium by the Logistic analysis. CONCLUSION:The expression of VEGF,SDF-1,Ki-67,PCNA and survivin in tissue of patients with pterygium all show abnormal state,and those indexes all have close relation to pterygium.

  11. KI-Aikido for Handicapped Students at Leeward Community College: Theory and Practice.

    Science.gov (United States)

    MacGugan, Kirk

    In an effort to provide physical education instruction for handicapped students, Leeward Community College implemented, on a pilot basis, a non-credit course in KI-Aikido, an oriental martial art which combines theory and exercise toward the goal of controlling the body through the power of the mind. The course, offered to both handicapped and…

  12. Differential effects of the KiVa anti-bullying program on popular and unpopular bullies

    NARCIS (Netherlands)

    Garandeau, Claire F.|info:eu-repo/dai/nl/380715066; Lee, Ihno A.; Salmivalli, Christina

    2014-01-01

    This study utilized data from the evaluation of the Finnish KiVa program in testing the prediction that school bullies' high perceived popularity would impede the success of anti-bullying interventions. Multiple-group structural equation modeling (SEM) analyses were conducted on a subsample of 911

  13. Tallink kaalub müüki pandud Silja Line'i ostu / Priit Rajalo

    Index Scriptorium Estoniae

    Rajalo, Priit, 1975-

    2005-01-01

    Soome Silja Oy AB omanikfirma Sea Containers otsustas 2. novembril Silja Line'i müüki panna, kuna laevafirma kasumlikkus on järsult vähenenud. Tallink Grupi finantsdirektori Janek Stalmeistri sõnul on Tallinki võimalikku ostuhuvi Silja Line'i vastu vara veel kommenteerida. Lisa: Silja laevad

  14. Kriitikud hindavad Cannes'is seni enim Kaurismäki filmi / Jaan Ruus

    Index Scriptorium Estoniae

    Ruus, Jaan, 1938-2017

    2011-01-01

    64. Cannes'i filmifestivalil seni enim köitnud filmidest, pikemalt Aki Kaurismäki filmist "Sadam" ("Le Havre"). Lühidalt enim vaidlusi tekitanud ameerika režissööri Terrence Malicki filmist "Elupuu" ("The Tree of Life") ja taani režissööri Lars von Trieri filmist "Melanhoolia" ("Melancholia")

  15. Immunohistochemical Study of ER, PR, Ki67 and p53 in Endometrial Hyperplasias and Endometrial Carcinomas.

    Science.gov (United States)

    Masjeed, Nayar Musfera Abdul; Khandeparkar, Siddhi Gaurish Sinai; Joshi, Avinash R; Kulkarni, Maithili Mandar; Pandya, Nidhi

    2017-08-01

    Endometrial carcinoma is the second most common gynecologic malignancy in the developing countries. Endometrial Hyperplasia (EH) is a precursor to Endometrioid Adenocarcinoma (EMAC). A 23% of Atypical Hyperplasias (AEH) progress to EMAC. This study was undertaken to analyse ER, PR, p53 and Ki67 in EH and endometrial carcinomas and attempt correlation with clinical and histopathological findings. The present study was conducted over a period of seven years. A manual tissue array technique was employed for cases subjected to IHC. Analysis of the expression of IHC markers (ER, PR, p53, Ki67) in EH and endometrial carcinoma was attempted. Results were subjected to statistical analysis. The results were considered to be significant when the p-value endometrial carcinoma were included in the study. EH (75.22%) was more common than endometrial carcinoma (24.78%). Among 28 cases of endometrial carcinomas, EMAC was most common (78.57%) followed by Clear Cell Carcinoma (CCC) (14.28%), and Uterine Serous Carcinoma (USC) (7.14%). ER and PR expression decreased as lesion progressed from EH to EMAC. ER and PR expression was negative in USC and CCC. The p53 expression and mean Ki67 labelling index increased as the severity of lesion increased from EH to endometrial carcinoma. The ER, PR, p53, Ki67 IHC markers may be included in every case of endometrial carcinoma to understand the tumour biological behavior which in turn could help individual treatment strategies.

  16. Analysis of the Ki-67 index in the vaginal epithelium of castrated rats treated with tamoxifen.

    Science.gov (United States)

    Nery-Aguiar, Afif Rieth; Aguiar, Yousef Qathaf; Conde Júnior, Airton Mendes; Alencar, Airlane Pereira; Tavares, Cleciton Braga; Lopes-Costa, Pedro Vitor; Nazário, Afonso Celso; da Silva, Benedito Borges

    2016-02-01

    Vaginal atrophy and breast cancer are common conditions in postmenopausal women and tamoxifen is the standard endocrine treatment for hormone-sensitive tumors. The present study aimed to assess the effect of tamoxifen on Ki-67 protein expression in the vaginal epithelium of castrated rats. Forty Wistar-Hannover adult, virgin, castrated rats were randomly divided into two groups, group I (control, n=20) and group II (tamoxifen, n=20), receiving 0.5 ml of propylene glycol and 250 µg of tamoxifen diluted in 0.5 ml of propylene glycol, respectively, daily by gavage for 30 days. On the 31st day, the rats were euthanized and their vaginas were removed and fixed in 10% buffered formalin for the immunohistochemical study of Ki-67 protein expression. Data were analyzed by the Levene and Student's t tests (p<0.05). The mean index of Ki-67 expression in the rat vagina of groups I and II was 4.04±0.96 and 26.86±2.19, respectively (p<0.001). According to the results of the present study, tamoxifen, at the dose and treatment length used, induced a significant increase in the cell proliferation of the vaginal mucosa in castrated rats, as evaluated by Ki-67 protein expression.

  17. Differences in Expression of EGFR, Ki67 and p-EPK in Oral Cavity ...

    African Journals Online (AJOL)

    Purpose: To evaluate the expression of EGFR, Ki67, and p-EPK in oral cavity and oropharyngeal cancers, and to investigate their clinical significance as prognostic markers. Methods: One hundred patients who underwent curative surgery for oral cavity or oropharyngeal squamous cell carcinoma in a Chinese People's ...

  18. The National Heritage of Ki Hadjar Dewantara in Tamansiswa about Culture-Based Education and Learning

    Science.gov (United States)

    Towaf, Siti Malikhah

    2016-01-01

    Global interdependence is a reality; in the security, economics, politics, socio-culture, and especially in the education of a nation;. Relevant to the need for an international dialog on education, this study tries to explore: 1) the concepts of culture-based education and learning of Ki Hadjar Dewantara (KHD) in Tamansiswa, 2) the results of…

  19. Hubungan antara Imunoekspresi Ki-67 dan Risiko Agresivitas Tumor pada Gastrointestinal Stromal Tumor

    Directory of Open Access Journals (Sweden)

    Herry Yulianti

    2015-12-01

    Full Text Available Gastrointestinal stromal tumor (GIST is the most common mesenchymal tumor of the gastrointestinal tract, and arises from intestinal cells of Cajal localized in the muscular layer of the digestive tract, which functions as pacemaker cells in regulating intestinal motility. The incidence of GIST is about 3−5% of all soft tissue sarcomas. Gastrointestinal stromal tumor can occur along the gastrointestinal tract and predominantly in middle-aged and older persons, with a median age between 50 and 60 years. Histologically, there are three categories of GIST morphology such as spindle cells, epitheloid, and mixed type. A spesific marker of GIST is cluster of differentiation (CD117, which has good sensitivity and immunoreactive in 95% of GIST. The expression of Ki-67 correlates with proliferative activities and can be detected in G1, S, G2, and M phases of cell cycle but not in G0 phase. The aim of this study was to assessthe correlation between the risk of aggressive behaviors and proliferative activities as measured by Ki-67 in tumors confirmed as GIST by CD117. The method of this study was cross-sectional, performed on 29 cases of GIST from the Department of Pathology Anatomy Dr. Hasan Sadikin General Hospital/Faculty of Medicine Universitas Padjadjaran, Santo Borromeus Hospital, Immanuel Hospital, and Santosa Hospital between 2007−2012. A section from paraffin embedded tissue of 55 cases of GIST was stained with hematoxylin eosin for histological and immunohistochemical evaluations using monoclonal antibody CD117 to confirm the diagnosis of GIST. There were 29 positive cases for CD117. Further staining was performed using monoclonal antibody Ki-67. The categorized positive cells of immunoexpression of CD117 showed brown particles inside cytoplasma and the immunoexpression of Ki-67 was assessed by identification of nuclear brown staining of neoplastic cells. The result showed that there were significant correlations between the risk of tumor

  20. Ki-67 Contributes to Normal Cell Cycle Progression and Inactive X Heterochromatin in p21 Checkpoint-Proficient Human Cells.

    Science.gov (United States)

    Sun, Xiaoming; Bizhanova, Aizhan; Matheson, Timothy D; Yu, Jun; Zhu, Lihua Julie; Kaufman, Paul D

    2017-09-01

    The Ki-67 protein is widely used as a tumor proliferation marker. However, whether Ki-67 affects cell cycle progression has been controversial. Here we demonstrate that depletion of Ki-67 in human hTERT-RPE1, WI-38, IMR90, and hTERT-BJ cell lines and primary fibroblast cells slowed entry into S phase and coordinately downregulated genes related to DNA replication. Some gene expression changes were partially relieved in Ki-67-depleted hTERT-RPE1 cells by codepletion of the Rb checkpoint protein, but more thorough suppression of the transcriptional and cell cycle defects was observed upon depletion of the cell cycle inhibitor p21. Notably, induction of p21 upon depletion of Ki-67 was a consistent hallmark of cell types in which transcription and cell cycle distribution were sensitive to Ki-67; these responses were absent in cells that did not induce p21. Furthermore, upon Ki-67 depletion, a subset of inactive X (Xi) chromosomes in female hTERT-RPE1 cells displayed several features of compromised heterochromatin maintenance, including decreased H3K27me3 and H4K20me1 labeling. These chromatin alterations were limited to Xi chromosomes localized away from the nuclear lamina and were not observed in checkpoint-deficient 293T cells. Altogether, our results indicate that Ki-67 integrates normal S-phase progression and Xi heterochromatin maintenance in p21 checkpoint-proficient human cells. Copyright © 2017 American Society for Microbiology.

  1. VizieR Online Data Catalog: KiDS-ESO-DR2 multi-band source catalog (de Jong+, 2015)

    NARCIS (Netherlands)

    de Jong, J. T. A.; Verdoes Kleijn, G. A.; Boxhoorn, D. R.; Buddelmeijer, H.; Capaccioli, M.; Getman, F.; Grado, A.; Helmich, E.; Huang, Z.; Irisarri, N.; Kuijken, K.; La Barbera, F.; McFarland, J. P.; Napolitano, N. R.; Radovich, M.; Sikkema, G.; Valentijn, E. A.; Begeman, K. G.; Brescia, M.; Cavuoti, S.; Choi, A.; Cordes, O.-M.; Covone, G.; Dall'Ora, M.; Hildebrandt, H.; Longo, G.; Nakajima, R.; Paolillo, M.; Puddu, E.; Rifatto, A.; Tortora, C.; van Uitert, E.; Buddendiek, A.; Harnois-Deraps, J.; Erben, T.; Eriksen, M. B.; Heymans, C.; Hoekstra, H.; Joachimi, B.; Kitching, T. D.; Klaes, D.; Koopmans, L. V. E.; Koehlinger, F.; Roy, N.; Sifon, C.; Schneider, P.; Sutherland, W. J.; Viola, M.; Vriend, W.-J.

    2017-01-01

    KiDS data releases consist of ~1 square degree tiles that have been successfully observed in all four survey filters (u,g,r,i). The second data release (KiDS-ESO-DR2) was available in February 2015 and contains imaging data, masks and single-band source lists for all tiles observed in all four

  2. Hollow-Fiber Spacesuit Water Membrane Evaporator

    Science.gov (United States)

    Bue, Grant; Trevino, Luis; Tsioulos, Gus; Mitchell, Keith; Settles, Joseph

    2013-01-01

    The hollow-fiber spacesuit water membrane evaporator (HoFi SWME) is being developed to perform the thermal control function for advanced spacesuits and spacecraft to take advantage of recent advances in micropore membrane technology in providing a robust, heat-rejection device that is less sensitive to contamination than is the sublimator. After recent contamination tests, a commercial-off-the-shelf (COTS) micro porous hollow-fiber membrane was selected for prototype development as the most suitable candidate among commercial hollow-fiber evaporator alternatives. An innovative design that grouped the fiber layers into stacks, which were separated by small spaces and packaged into a cylindrical shape, was developed into a full-scale prototype for the spacesuit application. Vacuum chamber testing has been performed to characterize heat rejection as a function of inlet water temperature and water vapor back-pressure, and to show contamination resistance to the constituents expected to be found in potable water produced by the wastewater reclamation distillation processes. Other tests showed tolerance to freezing and suitability to reject heat in a Mars pressure environment. In summary, HoFi SWME is a lightweight, compact evaporator for heat rejection in the spacesuit that is robust, contamination- insensitive, freeze-tolerant, and able to reject the required heat of spacewalks in microgravity, lunar, and Martian environments. The HoFi is packaged to reject 810 W of heat through 800 hours of use in a vacuum environment, and 370 W in a Mars environment. The device also eliminates free gas and dissolved gas from the coolant loop.

  3. Evaporation characteristics of ETBE-blended gasoline.

    Science.gov (United States)

    Okamoto, Katsuhiro; Hiramatsu, Muneyuki; Hino, Tomonori; Otake, Takuma; Okamoto, Takashi; Miyamoto, Hiroki; Honma, Masakatsu; Watanabe, Norimichi

    2015-04-28

    To reduce greenhouse gas emissions, which contribute to global warming, production of gasoline blended with ethyl tert-buthyl ether (ETBE) is increasing annually. The flash point of ETBE is higher than that of gasoline, and blending ETBE into gasoline will change the flash point and the vapor pressure. Therefore, it is expected that the fire hazard caused by ETBE-blended gasoline would differ from that caused by normal gasoline. The aim of this study was to acquire the knowledge required for estimating the fire hazard of ETBE-blended gasoline. Supposing that ETBE-blended gasoline was a two-component mixture of gasoline and ETBE, we developed a prediction model that describes the vapor pressure and flash point of ETBE-blended gasoline in an arbitrary ETBE blending ratio. We chose 8-component hydrocarbon mixture as a model gasoline, and defined the relation between molar mass of gasoline and mass loss fraction. We measured the changes in the vapor pressure and flash point of gasoline by blending ETBE and evaporation, and compared the predicted values with the measured values in order to verify the prediction model. The calculated values of vapor pressures and flash points corresponded well to the measured values. Thus, we confirmed that the change in the evaporation characteristics of ETBE-blended gasoline by evaporation could be predicted by the proposed model. Furthermore, the vapor pressure constants of ETBE-blended gasoline were obtained by the model, and then the distillation curves were developed. Copyright © 2015 Elsevier B.V. All rights reserved.

  4. Predicting Potential Evaporation in Topographically Complex Terrain

    Science.gov (United States)

    Koohafkan, M.; Thompson, S. E.; Hamilton, M. P.

    2012-12-01

    Predicting and understanding the water cycle in topographically complex terrain poses challenges for upscaling point-scale measurements of water and energy balance and for downscaling observations made from remote sensing or predictions made via global circulation models. This study evaluates hydrologic and climate data drawn from a spatially-distributed wireless sensor network at the Blue Oak Ranch Reserve near San Jose, California to investigate the influence of topographic variation, landscape position, and local ecology (vegetation) on one core component of the water balance: potential evaporation. High-resolution observations of solar radiation, ambient temperature, wind speed, and relative humidity are combined with canopy maps generated from LiDAR flyovers to develop spatially-distributed predictions of potential evaporation. These data are compared to estimates of EP based on inverse modeling of surface soil moisture data. Preliminary results suggest that the spatial structure of microclimate at Blue Oak Ranch Reserve is dominated by variations around the elevation gradient, with strong nocturnal inversions hypothesized to reflect the influence of the coastal marine layer. Estimates of EP based on the Penman-Monteith equation suggest that EP could vary by up to a factor of 5 across the site, with differences in vapor pressure deficit and canopy height largely responsible for this variability. The results suggest that a) large differences in the timing and magnitude of water stress could arise in topographically complex terrain due to localized differences in energy balance, and b) both localized and regional effects need to be accounted for when downscaling climate data over topographically complex sites. 2) Color map showing preliminary estimates of annual EP incorporating canopy information (spatially-distributed values of aerodynamic resistance and LAI) drawn from LiDAR imagery. The effect of the resistance on the dynamics is striking in its ability to

  5. Theoretical prediction of new C-Si alloys in {\\boldsymbol{C}}2/{\\boldsymbol{m}}-20 structure

    Science.gov (United States)

    Xu, Xiangyang; Chai, Changchun; Fan, Qingyang; Yang, Yintang

    2017-04-01

    We study structural, mechanical, and electronic properties of C20, Si20 and their alloys (C16Si4, C12Si8, C8Si12, and C4 {{Si}}16) in C2/m structure by using density functional theory (DFT) based on first-principles calculations. The obtained elastic constants and the phonon spectra reveal mechanical and dynamic stability. The calculated formation enthalpy shows that the C-Si alloys might exist at a specified high temperature scale. The ratio of B/G and Poisson’s ratio indicate that these C-Si alloys in C2/m-20 structure are all brittle. The elastic anisotropic properties derived by bulk modulus and shear modulus show slight anisotropy. In addition, the band structures and density of states are also depicted, which reveal that C20, C16Si4, and Si20 are indirect band gap semiconductors, while C8Si12 and C4Si16 are semi-metallic alloys. Notably, a direct band gap semiconductor (C12Si8) is obtained by doping two indirect band gap semiconductors (C20 and Si20). Project supported by the National Natural Science Foundation of China (Grant No. 61474089) and the Open Fund of Key Laboratory of Complex Electromagnetic Environment Science and Technology, China Academy of Engineering Physics (Grant No. 2015-0214.XY.K).

  6. Light particle evaporation from dynamical systems

    Energy Technology Data Exchange (ETDEWEB)

    Aleshin, V.P.; Sidorenko, B. [Institute for Nuclear Research, Kiev (Ukraine); Centelles, M.; Vinas, X. [Departament d`Estructura i Constituents de la Materia, Facultat de Fisica, Universitat de Barcelona, Barcelona (Spain)

    1997-01-01

    For the statistical particle-evaporation model to be applicable to particle emission from dynamical time-evolving systems, the system should closely follow the quasistatic path, which represents a sequence of conditional equilibrium shapes. We show that quasifission paths predicted by the one-body dissipation dynamics satisfy this requirement all the way from the contact point to the scission point, excluding short time intervals spent near the contact point (when neck fills in) and during separation (when waist develops). (author) 17 refs, 2 figs

  7. Lesion isolation by circumferential submucosal incision prior to endoscopic mucosal resection (CSI-EMR) substantially improves en bloc resection rates for 40-mm colonic lesions.

    Science.gov (United States)

    Moss, A; Bourke, M J; Tran, K; Godfrey, C; McKay, G; Chandra, A P; Sharma, S

    2010-05-01

    En bloc resection is preferred for colonic laterally spreading tumors, but is limited to 20 mm with endoscopic mucosal resection (EMR) using normal saline submucosal injection. Our aims were to compare the efficacy and safety of circumferential submucosal incision prior to EMR (CSI-EMR) versus conventional EMR for en bloc resection of artificial lesions 40 x 40 mm in size using submucosal injection of succinylated gelatin in a porcine colon model. Two areas of normal rectosigmoid mucosa measuring 40 x 40 mm were marked with soft coagulation for en bloc resection in each of 10 pigs. By alternate allocation, one was removed with conventional snare-based EMR following submucosal injection of succinylated gelatin. The other was circumferentially incised using an insulated-tip knife, followed by submucosal succinylated gelatin injection followed by EMR of the isolated area. All procedures were performed by a single endoscopist with significant experience of EMR but none of endoscopic submucosal dissection (ESD). Euthanasia and colectomy were performed on day 10. Specimens and ex vivo colon resection sites were examined by a specialist gastrointestinal histopathologist blinded to the technique used. En bloc excision rates were 70 % for CSI-EMR vs. 0 % for conventional EMR ( P = 0.016). The median number of resections was 1 (interquartile range, IQR: 1-2) for CSI-EMR vs. 4 (3 - 6) for EMR ( P CSI-EMR vs. 37 x 32 mm for EMR ( P = 0.001). Overall procedure duration (mean +/- SD) was 30.3 +/- 19.8 minutes for CSI-EMR vs. 12.4 +/- 6.8 minutes ( P = 0.003) for EMR. The mean duration of the final 5 CSI-EMRs was 17 minutes, with a statistically significant learning effect R = -0.7, P = 0.025. No perforations or bleeding occurred. All animals were euthanased on day 10. Histologically, CSI-EMR resulted in larger specimens and deeper submucosal resections. CSI-EMR with submucosal injection of succinylated gelatin is safe and superior to conventional EMR, consistently resulting in

  8. KiDS-450: testing extensions to the standard cosmological model

    Science.gov (United States)

    Joudaki, Shahab; Mead, Alexander; Blake, Chris; Choi, Ami; de Jong, Jelte; Erben, Thomas; Fenech Conti, Ian; Herbonnet, Ricardo; Heymans, Catherine; Hildebrandt, Hendrik; Hoekstra, Henk; Joachimi, Benjamin; Klaes, Dominik; Köhlinger, Fabian; Kuijken, Konrad; McFarland, John; Miller, Lance; Schneider, Peter; Viola, Massimo

    2017-10-01

    We test extensions to the standard cosmological model with weak gravitational lensing tomography using 450 deg2 of imaging data from the Kilo Degree Survey (KiDS). In these extended cosmologies, which include massive neutrinos, non-zero curvature, evolving dark energy, modified gravity and running of the scalar spectral index, we also examine the discordance between KiDS and cosmic microwave background (CMB) measurements from Planck. The discordance between the two data sets is largely unaffected by a more conservative treatment of the lensing systematics and the removal of angular scales most sensitive to non-linear physics. The only extended cosmology that simultaneously alleviates the discordance with Planck and is at least moderately favoured by the data includes evolving dark energy with a time-dependent equation of state (in the form of the w0 - wa parametrization). In this model, the respective S_8=σ _8√{Ω m/0.3} constraints agree at the 1σ level, and there is 'substantial concordance' between the KiDS and Planck data sets when accounting for the full parameter space. Moreover, the Planck constraint on the Hubble constant is wider than in Λ cold dark matter (ΛCDM) and in agreement with the Riess et al. (2016) direct measurement of H0. The dark energy model is moderately favoured as compared to ΛCDM when combining the KiDS and Planck measurements, and marginalized constraints in the w0-wa plane are discrepant with a cosmological constant at the 3σ level. KiDS further constrains the sum of neutrino masses to 4.0 eV (95% CL), finds no preference for time or scale-dependent modifications to the metric potentials, and is consistent with flatness and no running of the spectral index.

  9. EGFR, CD10 and proliferation marker Ki67 expression in ameloblastoma: possible role in local recurrence

    Directory of Open Access Journals (Sweden)

    Abdel-Aziz Azza

    2012-02-01

    Full Text Available Abstract Background Ameloblastoma is an odontogenic neoplasm characterized by local invasiveness and tendency towards recurrence. Aims Studying the role played by EGFR, CD10 and Ki67 in the recurrence of ameloblastoma. Methods This study was carried out on 22 retrospective cases of mandibular ameloblastoma from the period from Jan 2002 to Jan 2008 with follow up period until Jan 2011 (3 to 8 years follow up peroid. Archival materials were obtained from pathology department, Mansoura university. Paraffin sections of tumor tissue from all cases were submitted for routine H&E stains and immunohistochemistry using EGFR, CD10 and Ki67 monoclonal antibodies. Statistical analysis using of clinical data for all patients, tumor type, EGFR, CD10 and Ki67 expression in relation to recurrence were evaluated. Results Among the 22 cases, 10 cases were males and 12 were females with sex ratio 1:1.2. Age ranged from 34 to 59 years old with a mean age 44.18 year. Five cases showed local recurrence within studied period and proved by biopsy. No statistically significant relation was found between local recurrence and patient age, tumor size, tumor type, EGFR expression. There was a significant relation between CD10 expression as well as Ki67 labelling index and recurrence (P value = 0.003, 0.000 respectively. Conclusion Evaluation of CD10 and Ki67 status together with conventional histological evaluation can help in providing more information about the biologic behavior of the tumor, while EGFR could be a target of an expanding class of anticancer therapies. Since ameloblastomas are EGFR-positive tumors, anti-EGFR agents could be considered to reduce the size of large tumors and to treat unresectable tumors that are in close proximity to vital structures. Virtual Slides The virtual slide(s for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1902106905645651

  10. KI motifs of human Knl1 enhance assembly of comprehensive spindle checkpoint complexes around MELT repeats.

    Science.gov (United States)

    Krenn, Veronica; Overlack, Katharina; Primorac, Ivana; van Gerwen, Suzan; Musacchio, Andrea

    2014-01-06

    The KMN network, a ten-subunit protein complex, mediates the interaction of kinetochores with spindle microtubules and recruits spindle assembly checkpoint (SAC) constituents to halt cells in mitosis until attainment of sister chromatid biorientation. Two types of motifs in the KMN subunit Knl1 interact with SAC proteins. Lys-Ile (KI) motifs, found in vertebrates, interact with the TPR motifs of Bub1 and BubR1. Met-Glu-Leu-Thr (MELT) repeats, ubiquitous in evolution, recruit the Bub3/Bub1 complex in a phosphorylation-dependent manner. The exact contributions of KI and MELT motifs to SAC signaling and chromosome alignment are unclear. We report here that KI motifs cooperate strongly with the neighboring single MELT motif in the N-terminal 250 residues (Knl1(1-250)) of human Knl1 to seed a comprehensive assembly of SAC proteins. In cells depleted of endogenous Knl1, kinetochore-targeted Knl1(1-250) suffices to restore SAC and chromosome alignment. Individual MELT repeats outside of Knl1(1-250), which lack flanking KI motifs, establish qualitatively similar sets of interactions, but less efficiently. MELT sequences on Knl1 emerge from our analysis as the platforms on which SAC complexes become assembled. Our results show that KI motifs are enhancers of MELT function in assembling SAC signaling complexes, and that they might have evolved to limit the expansion of MELT motifs by providing a more robust mechanism of SAC signaling around a single MELT. We shed light on the mechanism of Bub1 and BubR1 recruitment and identify crucial questions for future studies. Copyright © 2014 Elsevier Ltd. All rights reserved.

  11. Danilo Kiš and the Hungarian Holocaust: The Early Novel Psalm 44

    Directory of Open Access Journals (Sweden)

    John K. Cox

    2012-01-01

    Full Text Available Danilo Kiš's little known second novel, Psalm 44 (1962 is his first major prose work about the Holocaust. This novel was published for the first time in Hungarian translation in 1966 and English translation in 2012. The novel is quite different from Kiš's later works on the Holocaust, the autobiographical trilogy comprising Early Sorrows, Garden, Ashes, and Hourglass. The first difference is in setting. In Psalm 44, a number of important flashbacks take place in Újvidék/Novi Sad, the region of northern Serbia (then Yugoslavia under Hungarian occupation after 1941; much of the rest of the book takes place in Auschwitz and associated camps in Poland. The amount of Hungarian material is significant, but the inclusion of so much material from Auschwitz is not found elsewhere in Kiš 's oeuvre. The second difference is in the author's graphic portrayal of gruesome atrocities. For the literary historian, Psalm 44 is an important milestone in the development of Kiš 's thematic and stylistic inventory. For other historians, the novel functions in part as a microhistory of the Újvidék massacres (the "Cold Days" of early 1942. Kiš 's quest to find his own voice to attempt to convey the tragedy of the Holocaust—as important for the entire human family and the very region of Central Europe as it was for his own family—finds a parallel expression in the confusion, exhaustion, and skepticism of the characters in this novel.

  12. Correlation of fluorodeoxyglucose uptake and tumor-proliferating antigen Ki-67 in lymphomas

    Directory of Open Access Journals (Sweden)

    Yi Shou

    2012-01-01

    Full Text Available Objective: To investigate the correlation between cellular proliferation and the fluorodeoxyglucose (FDG uptake in positron emission tomography/computed tomography (PET/CT imaging by comparing 50 cases of different subtypes of lymphoma. Materials and Methods: Fifty cases of lymphomas were collected. Each case was labeled with Ki-67 stain, a marker of cellular proliferation, and a PET/CT examination was performed. All lymphoma cases were sorted according to the World Health Organization′s classification, and the International Non-Hodgkin′s Lymphoma Working Formulation was used to differentiate groups of large and small cell non-Hodgkin′s lymphoma. The Ki-67 staining was described as slight, mild, middle, or strong according to the nuclear staining of positive cells. FDG uptake by lesions in PET/CT images was semi-quantitatively analyzed to calculate the average standard uptake value. The statistics software SPSS13.0 was used to calculate the mean and standard deviation of the FDG uptake value of the lymphoma subtypes, the difference between the large and small cell lymphoma group with a Student′s t-test, and the correlation between the Ki-67 level and FDG uptake of lesion with a Spearman′s analysis. Results: The FDG uptake value of large cell origin lymphoma was significantly higher than that of small cell origin lymphoma (t = 6.19, P < 0.01. The correlation coefficients between the Ki-67 level and FDG uptake value in lymph nodal and extranodal lesions was 0.750 and 0.843, respectively. Conclusions: Ki-67 staining, a reflection of tumor-proliferation activity, was significantly related to the FDG uptake value in lymphoma lesions.

  13. Immunohistochemical expression of GLUT-1 and Ki-67 in chronic plaque psoriasis.

    Science.gov (United States)

    Abdou, Asmaa G; Maraee, Alaa H; Eltahmoudy, Mohamed; El-Aziz, Reem A

    2013-10-01

    Many inflammatory mediators and other biological markers are upregulated in psoriatic lesions; some of these alterations also persist in nonlesional skin. Glucose is the major source of energy for cells, and glucose transporter 1 is the most common glucose transporter in humans (GLUT-1). The present study aimed at evaluating the pattern of expression of GLUT-1 and Ki-67 in psoriatic skin (involved and uninvolved) and correlating their expression with the clinicopathological parameters in the studied patients. This study was carried out on 30 patients presented with chronic plaque psoriasis and 10 apparently healthy volunteers as a control group. GLUT-1 was not expressed in epidermis of normal skin, whereas it was expressed in 76.6% of uninvolved and 86.7% of involved skin of psoriatic patients, where both the latter differed significantly regarding the intensity (P = 0.001) and localization (P = 0.001) of GLUT-1 expression. The percentage of Ki-67 expression did not differ significantly between involved and uninvolved skin of psoriatic patients, but they were higher than that of normal skin of control group. Nucleolar pattern of Ki-67 expression was significantly associated with male sex (P = 0.05), marked parakeratosis (P = 0.01), and marked angiogenesis (P = 0.05). GLUT-1 expression was associated with degree of acanthosis and percentage of Ki-67 expression. From this study, GLUT-1 is upregulated in psoriatic epidermis and may be involved in facilitation of keratinocyte proliferation in psoriasis. Nucleolar pattern of Ki-67 is an indicator of progressive keratinocyte proliferation in psoriasis.

  14. Evaporation dynamics from wetted porous surfaces affected by internal drainage

    Science.gov (United States)

    Lehmann, Peter; Fuchs, Josefa; Dehaspe, Joni; Breitenstein, Daniel; Wunderli, Hans; Or, Dani

    2017-04-01

    Land surface evaporation dynamics following periodic rainfall events is complicated by liquid phase redistribution and concurrent internal drainage. The maintenance of constant and high evaporation rates (stage 1 evaporation) is predicated on water supply to the surface via continuous capillary pathways up to a characteristic depth defined by porous media properties. The objective is to extend the description to realistic conditions where evaporation and internal drainage occur concurrently. Column experiments have shown that evaporative losses were drastically reduced when drainage takes place. For initially high water content (and hydraulic conductivity) drainage dominates and shortens opportunity for stage 1 evaporation. A range of intermediate results emerges in which transition to stage 2 evaporation depends on initial conditions and soil properties. We derived a new definition of evaporative characteristic length that links soil hydraulic properties and initial conditions with predicted evaporative losses from wetted land surface. Experiments and theoretical considerations confirm the existence of an optimal water content defining conditions for maximal evaporative losses during stage 1.

  15. Utility of P16 expression and Ki-67 proliferation index in ASCUS and ASC-H pap tests.

    Science.gov (United States)

    Toll, Adam D; Kelly, Deidra; Maleki, Zahra

    2014-07-01

    Current cervical screening uses a combination of cytology and high-risk human papillomavirus (HR-HPV) analysis in cases of atypical squamous cells of undetermined significance (ASCUS) and atypical squamous cells cannot exclude high-grade intraepithelial lesion (ASC-H). These diagnoses are subject to interobserver variability and HR-HPV analysis can be limited by sampling inadequacy. This study correlates immunoexpression of P16 and Ki-67 in residual cervicovaginal material against cytology category and HR-HPV status. Eighteen pap tests were selected: 8 ASCUS, 4 ASC-H, and 6 controls (2 LSIL and 4 HSIL). Digene Hybrid Capture II test was used to detect HR-HPV. The cytospins were stained for P16/Ki-67. Pap tests, P16, Ki-67, HR-HPV result and available biopsies were correlated. P16 expression correlated with HR-HPV status in 15/17 cases. Discordant cases (1 ASCUS and 1 ASC-H) were +P16/-HR-HPV. Ki-67 correlated with HR-HPV in 8/15 cases. Discordant cases were +HR-HPV/- Ki-67 (HSIL, LSIL, and ASC-H one each), and -HR-HPV/+Ki-67 (3 ASCUS, 1 LSIL, 1 ASC-H). Two cases were + P16/+ Ki-67/- HR-HPV. None were - P16/- Ki-67/+ HR-HPV. Histologic follow-up in 13 cases varied from benign to CIN III. Two cases of +P16/ - Ki-67/- HR-HPV had benign cervical biopcies. Although a small sample size, our findings show a utility for adjunct P16/ Ki-67 in addition to HR-HPV testing in cases of squamous atypia when HR-HPVs are non-detected due to low DNA copies, or missed lesions in cervical biopsies. © 2013 Wiley Periodicals, Inc.

  16. Association of pKi-67 with satellite DNA of the human genome in early G1 cells.

    Science.gov (United States)

    Bridger, J M; Kill, I R; Lichter, P

    1998-01-01

    pKi-67 is a nucleolar antigen that provides a specific marker for proliferating cells. It has been shown previously that pKi-67's distribution varies in a cell cycle-dependent manner: it coats all chromosomes during mitosis, accumulates in nuclear foci during G1 phase (type I distribution) and localizes within nucleoli in late G1 S and G2 phase (type II distribution). Although no function has as yet been ascribed to pKi-67, it has been found associated with centromeres in G1. In the present study the distribution pattern of pKi-67 during G1 in human dermal fibroblasts (HDFs) was analysed in more detail. Synchronization experiments show that in very early G1 cells pKi-67 coincides with virtually all satellite regions analysed, i.e. with centromeric (alpha-satellite), telomeric (minisatellite) and heterochromatic blocks (satellite III) on chromosomes 1 and Y (type Ia distribution). In contrast, later in the G1 phase, a smaller fraction of satellite DNA regions are found collocalized with pKi-67 foci (type Ib distribution). When all pKi-67 becomes localized within nucleoli, even fewer satellite regions remain associated with the pKi-67 staining. However, all centromeric and short arm regions of the acrocentric chromosomes, which are in very close proximity to or even contain the rRNA genes, are collocalized with anti-pKi-67 staining throughout the remaining interphase of the cell cycle. Thus, our data demonstrate that during post-mitotic reformation and nucleogenesis there is a progressive decline in the fraction of specific satellite regions of DNA that remain associated with pKi-67. This may be relevant to nucleolar reformation following mitosis.

  17. The proliferation marker pKi-67 becomes masked to MIB-1 staining after expression of its tandem repeats.

    Science.gov (United States)

    Schmidt, Mirko H H; Broll, Rainer; Bruch, Hans-Peter; Duchrow, Michael

    2002-11-01

    The Ki-67 antigen, pKi-67, is one of the most commonly used markers of proliferating cells. The protein can only be detected in dividing cells (G(1)-, S-, G(2)-, and M-phase) but not in quiescent cells (G(0)). The standard antibody to detect pKi-67 is MIB-1, which detects the so-called 'Ki-67 motif' FKELF in 9 of the protein's 16 tandem repeats. To investigate the function of these repeats we expressed three of them in an inducible gene expression system in HeLa cells. Surprisingly, addition of a nuclear localization sequence led to a complete absence of signal in the nuclei of MIB-1-stained cells. At the same time antibodies directed against different epitopes of pKi-67 did not fail to detect the protein. We conclude that the overexpression of the 'Ki-67 motif', which is present in the repeats, can lead to inability of MIB-1 to detect its antigen as demonstrated in adenocarcinoma tissue samples. Thereafter, in order to prevent the underestimation of Ki-67 proliferation indices in MIB-1-labeled preparations, additional antibodies (for example, MIB-21) should be used. Additionally, we could show in a mammalian two-hybrid assay that recombinant pKi-67 repeats are capable of self-associating with endogenous pKi-67. Speculating that the tandem repeats are intimately involved in its protein-protein interactions, this offers new insights in how access to these repeats is regulated by pKi-67 itself.

  18. Chromophore-assisted light inactivation of pKi-67 leads to inhibition of ribosomal RNA synthesis.

    Science.gov (United States)

    Rahmanzadeh, R; Hüttmann, G; Gerdes, J; Scholzen, T

    2007-06-01

    Expression of the nuclear Ki-67 protein (pKi-67) is strongly associated with cell proliferation. For this reason, antibodies against this protein are widely used as prognostic tools for the assessment of cell proliferation in biopsies from cancer patients. Despite this broad application in histopathology, functional evidence for the physiological role of pKi-67 is still missing. Recently, we proposed a function of pKi-67 in the early steps of ribosomal RNA (rRNA) synthesis. Here, we have examined the involvement of pKi-67 in this process by photochemical inhibition using chromophore-assisted light inactivation (CALI). Anti-pKi-67 antibodies were labelled with the fluorochrome fluorescein 5(6)-isothiocyanate and were irradiated after binding to their target protein. Performing CALI in vitro on cell lysates led to specific cross-linking of pKi-67. Moreover, the upstream binding factor (UBF) necessary for rRNA transcription was also partly subjected to cross-link formation, indicating a close spatial proximity of UBF and pKi-67. CALI in living cells, using micro-injected antibody, caused a striking relocalization of UBF from foci within the nucleoli to spots located at the nucleolar rim or within the nucleoplasm. pKi-67-CALI resulted in dramatic inhibition of RNA polymerase I-dependent nucleolar rRNA synthesis, whereas RNA polymerase II-dependent nucleoplasmic RNA synthesis remained almost unaltered. Our data presented here argue for a crucial role of pKi-67 in RNA polymerase I-dependent nucleolar rRNA synthesis.

  19. Theoretical and computational analyses of LNG evaporator

    Science.gov (United States)

    Chidambaram, Palani Kumar; Jo, Yang Myung; Kim, Heuy Dong

    2017-04-01

    Theoretical and numerical analysis on the fluid flow and heat transfer inside a LNG evaporator is conducted in this work. Methane is used instead of LNG as the operating fluid. This is because; methane constitutes over 80% of natural gas. The analytical calculations are performed using simple mass and energy balance equations. The analytical calculations are made to assess the pressure and temperature variations in the steam tube. Multiphase numerical simulations are performed by solving the governing equations (basic flow equations of continuity, momentum and energy equations) in a portion of the evaporator domain consisting of a single steam pipe. The flow equations are solved along with equations of species transport. Multiphase modeling is incorporated using VOF method. Liquid methane is the primary phase. It vaporizes into the secondary phase gaseous methane. Steam is another secondary phase which flows through the heating coils. Turbulence is modeled by a two equation turbulence model. Both the theoretical and numerical predictions are seen to match well with each other. Further parametric studies are planned based on the current research.

  20. Influence of Oil on Refrigerant Evaporator Performance

    Science.gov (United States)

    Jong-Soo, Kim; Nagata, Katsuya; Katsuta, Masafumi; Tomosugi, Hiroyuki; Kikuchi, Kouichiro; Horichi, Toshiaki

    To explore the quantitative effect of the lubrication oil on the thermal and hydraulic evaporator performance, the detailed structure of two-phase refrigerant (R11) and lubrication oil (Suniso 5GS) flow has been investigated. Experiment has been performed using a transparent tube 20mm in inner diameter and 2600mm in total length as main test section, which was heated by surrounding hot water bath. This water bath also functioned as the visual observation section of the transition of two-phase flow pattern. Oil mass concentration was controlled initially, and circulated into the system. The void fraction at the main test section was measured by direct volume measurement using so-called "Quick Closing Valve" method. Since the effect of oil on the transition of two-phase flow pattern is emphasized at the low flow rate, operation was made at relatively low mass velocity, 50 and 100 kg/m2·s, five different oil concentrations were taken. Throughout the experiment, the evaporation pressure was kept at 105 kPa. In general, when contamination of the lubrication oil happened, the void fraction was decreasing due to the change of viscosity and surface tension and the occurence of the foaming. To correlate the void fraction as function of quality, Zivi's expression was modified to include the effect of oil concentration. The agreement between the data and this proposed correlation was favorable. Finally, to take into account the effect of lubrication oil, the new flow pattern diagram was proposed.

  1. Analytical solution for soil water redistribution during evaporation process.

    Science.gov (United States)

    Teng, Jidong; Yasufuku, Noriyuki; Liu, Qiang; Liu, Shiyu

    2013-01-01

    Simulating the dynamics of soil water content and modeling soil water evaporation are critical for many environmental and agricultural strategies. The present study aims to develop an analytical solution to simulate soil water redistribution during the evaporation process. This analytical solution was derived utilizing an exponential function to describe the relation of hydraulic conductivity and water content on pressure head. The solution was obtained based on the initial condition of saturation and an exponential function to model the change of surface water content. Also, the evaporation experiments were conducted under a climate control apparatus to validate the theoretical development. Comparisons between the proposed analytical solution and experimental result are presented from the aspects of soil water redistribution, evaporative rate and cumulative evaporation. Their good agreement indicates that this analytical solution provides a reliable way to investigate the interaction of evaporation and soil water profile.

  2. Dynamic Models of Vacuum-Evaporator Plants for Dairy Industry

    Directory of Open Access Journals (Sweden)

    G. M. Airapetiants

    2009-01-01

    Full Text Available The paper studies problems of linearized dynamic models intended for synthesis of automatic temperature control systems and vacuum depth in vacuum evaporators. А single-casing vacuum evaporator plant is considered as an object of automatic control. Disturbance input channels are discerned and transfer functions permitting to determine laws of temperature and vacuum regulation and optimum parameters for setting automatic regulators used for various operational modes of vacuum-evaporator plants are obtained on the basis of the executed analysis.

  3. Two phase flow instabilities in horizontal straight tube evaporator

    OpenAIRE

    2010-01-01

    Abstract It is essential to ensure the stability of a refrigeration system if the oscillation in evaporation process is the primary cause for the whole system instability. This paper is concerned with an experimental investigation of two phase flow instabilities in a horizontal straight tube evaporator of a refrigeration system. The relationship between pressure drop and mass flow with constant heat flux and evaporation pressure is measured and determined. It is found that there is...

  4. CFD analysis of tube-fin 'no-frost' evaporators

    OpenAIRE

    Barbosa, Jr,Jader R; Hermes,Christian J. L; Melo,Cláudio

    2010-01-01

    The purpose of this paper is to assess some aspects of the design of evaporators for household refrigeration appliances using Computational Fluid Dynamics (CFD). The evaporators under study are tube-fin 'no-frost' heat exchangers with forced convection on the air-side and a staggered tube configuration. The calculation methodology was verified against experimental data for the heat transfer rate, thermal conductance and pressure drop obtained for two evaporators with different geometries. The...

  5. Automated characterization and counting of Ki-67 protein for breast cancer prognosis: A quantitative immunohistochemistry approach.

    Science.gov (United States)

    Mungle, Tushar; Tewary, Suman; Arun, Indu; Basak, Bijan; Agarwal, Sanjit; Ahmed, Rosina; Chatterjee, Sanjoy; Maity, Asok Kumar; Chakraborty, Chandan

    2017-02-01

    Ki-67 protein expression plays an important role in predicting the proliferative status of tumour cells and deciding the future course of therapy in breast cancer. Immunohistochemical (IHC) determination of Ki-67 score or labelling index, by estimating the fraction of Ki67 positively stained tumour cells, is the most widely practiced method to assess tumour proliferation (Dowsett et al. 2011). Accurate manual counting of these cells (specifically nuclei) due to complex and dense distribution of cells, therefore, becomes critical and presents a major challenge to pathologists. In this paper, we suggest a hybrid clustering algorithm to quantify the proliferative index of breast cancer cells based on automated counting of Ki-67 nuclei. The proposed methodology initially pre-processes the IHC images of Ki-67 stained slides of breast cancer. The RGB images are converted to grey, L*a*b*, HSI, YCbCr, YIQ and XYZ colour space. All the stained cells are then characterized by two stage segmentation process. Fuzzy C-means quantifies all the stained cells as one cluster. The blue channel of the first stage output is given as input to k-means algorithm, which provides separate cluster for Ki-67 positive and negative cells. The count of positive and negative nuclei is used to calculate the F-measure for each colour space. A comparative study of our work with the expert opinion is studied to evaluate the error rate. The positive and negative nuclei detection results for all colour spaces are compared with the ground truth for validation and F-measure is calculated. The F-measure for L*a*b* colour space (0.8847) provides the best statistical result as compared to grey, HSI, YCbCr, YIQ and XYZ colour space. Further, a study is carried out to count nuclei manually and automatically from the proposed algorithm with an average error rate of 6.84% which is significant. The study provides an automated count of positive and negative nuclei using L*a*b*colour space and hybrid

  6. Distribution of Evaporating CO2 in Parallel Microchannels

    DEFF Research Database (Denmark)

    Brix, Wiebke; Elmegaard, Brian

    2008-01-01

    The impact on the heat exchanger performance due to maldistribution of evaporating CO2 in parallel channels is investigated numerically. A 1D steady state simulation model of a microchannel evaporator is built using correlations from the literature to calculate frictional pressure drop and heat...... to results obtained using R134a as refrigerant, and it is found that the performance of the evaporator using CO2 is less affected by the maldistribution than the evaporator using R134a as refrigerant. For both cases studied, the impact of the maldistribution was very small for CO2....

  7. Method for improving accuracy in full evaporation headspace analysis.

    Science.gov (United States)

    Xie, Wei-Qi; Chai, Xin-Sheng

    2017-05-01

    We report a new headspace analytical method in which multiple headspace extraction is incorporated with the full evaporation technique. The pressure uncertainty caused by the solid content change in the samples has a great impact to the measurement accuracy in the conventional full evaporation headspace analysis. The results (using ethanol solution as the model sample) showed that the present technique is effective to minimize such a problem. The proposed full evaporation multiple headspace extraction analysis technique is also automated and practical, and which could greatly broaden the applications of the full-evaporation-based headspace analysis. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. Spacesuit Water Membrane Evaporator; An Enhanced Evaporative Cooling Systems for the Advanced Extravehicular Mobility Unit Portable Life Support System

    Science.gov (United States)

    Bue, Grant C.; Makinen, Janice V.; Miller, Sean.; Campbell, Colin; Lynch, Bill; Vogel, Matt; Craft, Jesse; Petty, Brian

    2014-01-01

    Spacesuit Water Membrane Evaporator - Baseline heat rejection technology for the Portable Life Support System of the Advanced EMU center dot Replaces sublimator in the current EMU center dot Contamination insensitive center dot Can work with Lithium Chloride Absorber Radiator in Spacesuit Evaporator Absorber Radiator (SEAR) to reject heat and reuse evaporated water The Spacesuit Water Membrane Evaporator (SWME) is being developed to replace the sublimator for future generation spacesuits. Water in LCVG absorbs body heat while circulating center dot Warm water pumped through SWME center dot SWME evaporates water vapor, while maintaining liquid water - Cools water center dot Cooled water is then recirculated through LCVG. center dot LCVG water lost due to evaporation (cooling) is replaced from feedwater The Independent TCV Manifold reduces design complexity and manufacturing difficulty of the SWME End Cap. center dot The offset motor for the new BPV reduces the volume profile of the SWME by laying the motor flat on the End Cap alongside the TCV.

  9. Spectroscopic imaging of the human liver using 3D CSI. Optimization and application in patients with metastatic uvea melanoma; Spektroskopische Bildgebung der menschlichen Leber mittels 3D-CSI. Etablierung und Anwendung bei Patienten mit metastasiertem Aderhautmelanom

    Energy Technology Data Exchange (ETDEWEB)

    Beer, M.; Winkelmann, V.; Stenzel, M.; Hahn, D.; Koestler, H. [Universitaetsklinikum Wuerzburg (Germany). Inst. fuer Roentgendiagnostik; Becker, J.C.; Broecker, E.B. [Universitaetsklinikum Wuerzburg (Germany). Klinik fuer Dermatologie, Venerologie und Allergologie; Terheyden, P. [Universitaetsklinikum Wuerzburg (Germany). Klinik fuer Dermatologie, Venerologie und Allergologie; Universitaetsklinikum Schleswig-Holstein, Kiel (Germany). Klinik fuer Dermatologie, Allergologie und Venerologie

    2009-01-15

    Purpose: {sup 31}P MR spectroscopy (MRS) allows the noninvasive assessment of metabolic alterations in tumors. Due to physical as well as technical limitations, mostly large and single voxels are used. We used a spatially resolved 31P MRS technique to characterize metabolic abnormalities inside and adjacent to liver metastases of patients with uvea melanoma. Materials and Methods: Optimization of 3D chemical shift imaging (3D CSI) was performed in healthy volunteers (n = 19; voxel size 25 ml). Patients (n = 8) with liver metastases were then examined. Cross sectional imaging was available for all patients. Results: Compared to healthy volunteers, the PME/PDE ratios of patients with liver metastasis were significantly higher (0.56 {+-} 0.30 vs. 0.39 {+-} 0.21; p < 0.05). A trend towards increased PME/beta ATP ratios (2.07 {+-} 1.83 vs. 1.02 {+-} 0.45; p = 0.12) and decreased Pi/PME ratios (0.57 {+-} 0.29 vs. 1.06 {+-} 0.58; p = 0.06) was also observed. Patients with metastases {>=} 5 cm showed significantly higher PME/PDE ratios (0.68 {+-} 0.17 vs. 0.45 {+-} 0.03; p < 0.05). Liver parenchyma adjacent to metastases did not show any significant changes compared to non-diseased tissue. Conclusion: 3D CSI allows the simultaneous analysis of metabolic alterations in diseased as well as in healthy human liver. Metastases show significant metabolic alterations. Thus, {sup 31}P MRS opens new possibilities for therapeutic monitoring. (orig.)

  10. Ki-ras gene mutations are invariably present in low-grade mucinous tumors of the vermiform appendix.

    Science.gov (United States)

    Zauber, Peter; Berman, Errol; Marotta, Stephen; Sabbath-Solitare, Marlene; Bishop, Timothy

    2011-07-01

    Low-grade mucinous tumors of the appendix appear to have a simple histological structure. Paradoxically, reports have suggested a greater frequency of Ki-ras gene mutation in these lesions than in more complex lesions such as benign colonic adenomas and carcinomas. We assessed several molecular genetic changes, including Ki-ras gene mutations, in a large series of low-grade mucinous tumors of the appendix. We retrospectively ascertained low-grade mucinous tumors of the appendix from computerized pathology records. Extracted DNA was analyzed for APC and DCC gene loss of heterozygosity, microsatellite instability and for the presence of Ki-ras gene mutation using standard molecular techniques. Controls consisted of normal appendices, other appendiceal neoplasms, and ovarian mucinous cystadenomas. A total of 31 low-grade appendiceal mucinous tumors were identified. All were microsatellite stable and none demonstrated loss of heterozygosity for the APC or DCC genes. By contrast, all 31 lesions contained a Ki-ras gene mutation. The presence of a Ki-ras gene mutation in all lesions, with no other molecular changes identified, strongly suggests a possible etiological role of the Ki-ras mutation in the development of this particular lesion of the appendix. Based on other work regarding intestinal bacteria, we hypothesize a relationship between chronic inflammation of the appendix from bacterial overgrowth and Ki-ras gene mutation.

  11. Biosorption of Cd(II) and Cs(I) from aqueous solution by live and dead cells of Saccharomyces carlsbergensis PTCC 5051.

    Science.gov (United States)

    Sayyadi, Shayan; Ahmady-Asbchin, Salman; Kamali, Kasra

    2017-03-21

    The biosorption characteristics of Cd(II) and Cs(I) using live and dead cells of Saccharomyces carlsbergensis PTCC 5051 as biosorbents have been investigated in the present research. The influence of different experimental parameters such as initial pH (pHi), shaking rate, sorption time and initial metal concentration was evaluated. The optimum pH was obtained as 4 for Cd(II) and 7 for Cs(I). The experimental adsorption data were fitted to the Langmuir linear equation adsorption model. The highest metal uptake values of 0.593 and 0.473 mmol g-1 were calculated for Cd(II) and Cs(I), respectively. The results of Fourier transform infrared analysis suggested the involvement of amine, carboxyl and hydroxyl groups during the biosorption process and also indicated that more functional groups were involved in the biosorption process of live adsorbents, compared with those linked to dead biomass. The results showed that the biomass of S. carlsbergensis PTCC 5051 is a suitable biosorbent for the removal of Cd(II) and Cs(I) from the aqueous solutions.

  12. The Chemistry Scoring Index (CSI: A Hazard-Based Scoring and Ranking Tool for Chemicals and Products Used in the Oil and Gas Industry

    Directory of Open Access Journals (Sweden)

    Tim Verslycke

    2014-06-01

    Full Text Available A large portfolio of chemicals and products is needed to meet the wide range of performance requirements of the oil and gas industry. The oil and gas industry is under increased scrutiny from regulators, environmental groups, the public, and other stakeholders for use of their chemicals. In response, industry is increasingly incorporating “greener” products and practices but is struggling to define and quantify what exactly constitutes “green” in the absence of a universally accepted definition. We recently developed the Chemistry Scoring Index (CSI which is ultimately intended to be a globally implementable tool that comprehensively scores and ranks hazards to human health, safety, and the environment for products used in oil and gas operations. CSI scores are assigned to products designed for the same use (e.g., surfactants, catalysts on the basis of product composition as well as intrinsic hazard properties and data availability for each product component. As such, products with a lower CSI score within a product use group are considered to have a lower intrinsic hazard compared to other products within the same use group. The CSI provides a powerful tool to evaluate relative product hazards; to review and assess product portfolios; and to aid in the formulation of products.

  13. Radicals and ions controlling by adjusting the antenna-substrate distance in a-Si:H deposition using a planar ICP for c-Si surface passivation

    Science.gov (United States)

    Zhou, H. P.; Xu, S.; Xu, M.; Xu, L. X.; Wei, D. Y.; Xiang, Y.; Xiao, S. Q.

    2017-02-01

    Being a key issue in the research and fabrication of silicon heterojunction (SHJ) solar cells, crystalline silicon (c-Si) surface passivation is theoretically and technologically intricate due to its complicate dependence on plasma characteristics, material properties, and plasma-material interactions. Here amorphous silicon (a-Si:H) grown by a planar inductively coupled plasma (ICP) reactor working under different antenna-substrate distances of d was used for the surface passivation of low-resistivity p-type c-Si. It is found that the microstructures (i.e., the crystallinity, Si-H bonding configuration etc.) and passivation function on c-Si of the deposited a-Si:H were profoundly influenced by the parameter of d, which primarily determines the types of growing precursors of SiHn/H contributing to the film growth and the interaction between the plasma and growing surface. c-Si surface passivation is analyzed in terms of the d-dependent a-Si:H properties and plasma characteristics. The controlling of radical types and ion bombardment on the growing surface through adjusting parameter d is emphasized.

  14. Instruments for assessing the burden of informal caregiving for stroke patients in clinical practice: a comparison of CSI, CRA, SCQ and self-rated burden

    NARCIS (Netherlands)

    van Exel, N. Job A.; Scholte op Reimer, Wilma J. M.; Brouwer, Werner B. F.; van den Berg, Bernard; Koopmanschap, Marc A.; van den Bos, Geertrudis A. M.

    2004-01-01

    Objective: To compare the feasibility, convergent and clinical validity of three commonly used burden scales: Caregiver Strain Index (CSI), Caregiver Reaction Assessment (CRA) and Sense of Competence Questionnaire (SCQ), with a self-developed single question on self-rated burden (SRB). Subjects:

  15. Measuring Somatic Complaints in Primary School Children: Validation and Revision of the German Children's Somatization Inventory (CSI) and its Parental Version.

    Science.gov (United States)

    Gulewitsch, Marco Daniel; Rosenkranz, Tabea; Barkmann, Claus; Schlarb, Angelika Anita

    2015-10-01

    The objective was a psychometric examination of a German translation of the Children's Somatization Inventory (CSI) and its parents' version (P-CSI) and a replication of the item selection process of Walker et al. in J Pediatr Psychol 34:430-440 [5] for their revised version to create shorter German versions. Based on a school sample of 1,539 parents and 731 children, we explored the psychometric properties and dimensionality of the original and a shortened revised version. A clinical sample of 70 parental reports served as an additional sample. Walker et al.'s item selection could be largely replicated. Dimensionality differed between samples and versions (original vs. revised), but original DSM-III symptom clusters could mostly be identified. Symptom intensity was associated with age and mental health. Internal consistency, test-retest- and inter-rater reliability were good. Both German versions, the CSI and the P-CSI can be regarded as a useful screening instrument for somatic complaints in children.

  16. Prognostic value of programmed death ligand 1, p53, and Ki-67 in patients with advanced stage colorectal cancer.

    Science.gov (United States)

    Wang, Lisha; Liu, Zebing; Fisher, Kurt W; Ren, Fei; Lv, Jiaojie; Davidson, Darrell D; Baldridge, Lee A; Du, Xiang; Cheng, Liang

    2017-08-04

    Current prognostic indicators are ineffective for identifying advanced stage colorectal cancer (CRC) patients with high risk of recurrence after surgical resection. We investigated the prognostic value of p53, Ki-67, and programmed death ligand 1 (PD-L1) in 254 patients with stage II and III CRC. The expression of p53 was positive in 63% of cases. Up-regulation of p53 was associated with smaller tumor size (P=.001) and higher Ki-67 labeling index (LI) (P=.031). The tumor Ki-67 LI was high (≥ 20%) in 197 (78%) of the patients. High Ki-67 LI was associated with higher TNM stage (P=.031), positive p53 expression (P=.031), and negative PD-L1 expression (P=.003). The five-year relapse-free survivals (RFS) were 53% and 89%, respectively, for the p53-positive and Ki-67 LI-high patients and the p53-negative and Ki-67 LI-low patients (Pp53 (P=.001), low Ki-67 LI (P=.006), low PD-L1 expression (P=.044), low TNM stage (Pp53 expression (hazard ratio [HR]: 2.48; 95% confidence interval: 1.34-4.59, P=.004), high Ki-67 LI (HR: 2.62; 95% CI: 1.12-6.14, P=.027) and high TNM stage (HR: 2.598, 95% CI: 1.55-4.37, Pp53 staining individually had significant prognostic value for patients with stage II and III CRC. Moreover, combining p53 H-score≥35 and Ki-67 LI≥20% identifies patients with poor clinical outcome. Copyright © 2017. Published by Elsevier Inc.

  17. [Expressions of cyclinB1, FHIT and Ki-67 in 336 gastric carcinoma patients and their clinicopathologic significance].

    Science.gov (United States)

    Li, Ya-Zhuo; Zhao, Po

    2009-09-08

    To investigate the expressions of cyclinB1, FHIT and Ki-67 in gastric carcinoma and their clinical significance. Immunohistochemistry (PV6000 method) was used to detect the expressions of cyclinB1, FHIT and Ki-67 in paraffin-embedded gastric carcinoma tissues of 336 cases and paracancerous normal mucosa of 60 cases. All cases were successfully followed up. The positive expression rates of cyclinB1, FHIT and Ki-67 in gastric carcinoma were 66.1% (222/336), 39.9% (134/336) and 58.3% (196/336) respectively. CyclinB1 and Ki-67 were all correlated with tumor size, differentiation degree, infiltrative depth, clinical stage, lymphatic invasion and distant metastasis (P < 0.05). And FHIT showed a correlation with differentiation degree, lymphatic invasion and clinical stage (P < 0.05). The 5-year survival rate of patients with positive cyclinB1 and Ki-67 expressions were both lower than those with negative expressions (P < 0.05), whereas FHIT had the opposite pattern (P = 0.025). The cyclinB1 expression in gastric carcinoma was positively correlated with the Ki-67 expression (r = 0.249, P = 0.0001). The expressions of cyclinB1 and Ki-67 in carcinoma were significantly higher than those in normal mucosa tissues (P < 0.05), but FHIT had the opposite pattern. Ki-67 was an independent prognostic indicator for post-operative survival time. CyclinB1, FHIT and Ki-67 may play significant roles in the occurrence and evolution of gastric carcinoma. And they can be used as useful indicators for clinical assessment of tumor biological behaviors and prognosis in patients with gastric carcinoma.

  18. The Nishino Breathing Method and Ki-energy (Life-energy: A Challenge to Traditional Scientific Thinking

    Directory of Open Access Journals (Sweden)

    Tsuyoshi Ohnishi

    2006-01-01

    Full Text Available The breathing method, which was developed and is being taught by Kozo Nishino, a Japanese Ki-expert, is for raising the levels of Ki-energy (life-energy or the vitality of an individual. It is neither a therapy nor a healing technique. However, many of his students have experienced an improvement in their health, and in some cases, they were able to overcome health problems by themselves. Since this is an interesting subject from the standpoint of complementary and alternative medicine (CAM, we have been collaborating with Nishino to conduct a scientific investigation of his Ki-energy. We found that Nishino's Ki-energy can inhibit cell division of cancer cells, protect isolated mitochondria from heat deterioration and reduce lipid peroxidation in heat-treated mitochondria. Although Ki-energy may consist of several different energy forms, we found that at least one of them is near-infrared radiation between the wavelength range of 0.8 and 2.7 µm. Another interesting observation at his school is the Taiki-practice (paired Ki-practice. During this practice, Nishino can ‘move’ his students without any physical contact. Many of them run, jump or roll on the floor when they receive his Ki-energy. We studied this and propose that ‘information’ is conveyed through the air between two individuals by Ki-energy. This may be called a five sense-independent, life-to-life communication by Ki. All of our results suggest that we should re-evaluate the Cartesian dualism (separation of mind and body which has been a fundamental principle of modern science for the past three centuries.

  19. Cracks formation during blood drop evaporation

    Science.gov (United States)

    Sobac, Benjamin; Brutin, David; Université de Provence Team

    2011-03-01

    We firstly presented the pattern formation occurring when drops of whole blood desiccate in a recent publication. The phenomena presented evidence to involve lots of physical field such as surface chemistry, haematolology, fluid mechanics, heat transfer, colloids science... All these mechanisms are acting together and produce an axisymetric and reproducible pattern. Dried cellular components are segregated and deposited by a capillary flow. During the evaporation, the system is slowly drying and cracks when stresses are too important leading to the final pattern observed. In this presentation, we will present the mechanisms involved in the formation of crack patterns. The phenomenon presented here with red blood cells as the main colloids involved is very similar to the drying of drop of nanoparticules. We will explain the common point and the differences encountered.

  20. Polonium evaporation from dilute liquid metal solutions

    CERN Document Server

    Rizzi, Matthias; Eichler, Robert; Türler, Andreas; Mendonça, Tania Melo; Stora, Thierry; Gonzalez Prieto, Borja; Aerts, Alexander; Schumann, Dorothea

    2014-01-01

    The evaporation behavior of polonium as one of the most hazardous radionuclides produced in spallation based neutron sources with liquid lead-bismuth targets has been quantified in this study. The normalized apparent vapor pressure, i.e. the Henry constant of polonium over liquid lead-bismuth eutectic was determined in the temperature range relevant for operation of such targets, i.e. 164-500 degrees C. For comparison and better fundamental understanding, the Henry constant of polonium over pure liquid bismuth was determined in a temperature range of 300-500 degrees C. The Henry constants of polonium in this temperature range were found to be orders of magnitude higher than expected from earlier studies at higher temperatures. Possible mechanisms responsible for this unexpected behavior are discussed.

  1. Sessile droplet evaporation on superheated superhydrophobic surfaces

    CERN Document Server

    Hays, Robb C; Maynes, Daniel; Webb, Brent W

    2013-01-01

    This fluid dynamics video depicts the evaporation of sessile water droplets placed on heated superhydrophobic (SH) surfaces of varying cavity fraction, F_c, and surface temperature, T_s, above the saturation temperature, T_sat. Images were captured at 10,000 FPS and are played back at 30 FPS in this video. Teflon-coated silicon surfaces of F_c = 0, 0.5, 0.8, and 0.95 were used for these experiments. T_s ranging from 110{\\deg}C to 210{\\deg}C were studied. The video clips show how the boiling behavior of sessile droplets is altered with changes in surface microstructure. Quantitative results from heat transfer rate experiments conducted by the authors are briefly discussed near the end of the video.

  2. Modeling and simulation of direct contact evaporators

    Directory of Open Access Journals (Sweden)

    Campos F.B.

    2001-01-01

    Full Text Available A dynamic model of a direct contact evaporator was developed and coupled to a recently developed superheated bubble model. The latter model takes into account heat and mass transfer during the bubble formation and ascension stages and is able to predict gas holdup in nonisothermal systems. The results of the coupled model, which does not have any adjustable parameter, were compared with experimental data. The transient behavior of the liquid-phase temperature and the vaporization rate under quasi-steady-state conditions were in very good agreement with experimental data. The transient behavior of liquid height was only reasonably simulated. In order to explain this partial disagreement, some possible causes were analyzed.

  3. Vacuum drying plant for evaporator concentrates

    Energy Technology Data Exchange (ETDEWEB)

    Benavides, E. [ENSA, Madrid (Spain)

    2001-07-01

    Volume reduction systems applied to evaporator concentrates in PWR and BWR save a significant amount of drums. The concentration to dry product is a technique that reaches the maximum volume reduction, compared to conventional techniques (cementation, polymerisation). Four Spanish N.P.P. (3 PWR and 1 BWR) have selected ENSA's process by means of fixed ''in drum vacuum drying system''. A 130-litre steel drum is used for drying without any additional requirement except vacuum resistance. This steel drum is introduced into a standard 200-litre drum. Five centimeters concrete shielding cylinder exists between both drums. Final package is classified as 19 GO according to ENRESA's acceptance code (dry waste with 5 cm concrete between 130-l and 200-l drum). The generation of cemented waste in five N.P.P. versus dried waste will be reduced 83%. This reduction will save a considerable amount in disposal costs. (authors)

  4. Capture of cenospheres by evaporating drops

    Science.gov (United States)

    Leong, K. H.; Ochs, Harry T.; Beard, K. V.

    The capture efficiency of evaporating cloud drops between 60 and 100 μm radius has been measured for 2 μm radius lithium carbonate hollow particles (cenospheres). Since the effective particle density is low compared to a 2-μm solid particle the cenospheres have reduced sedimentation speeds and a negligible inertial capture efficiency. The particles are sufficiently large ( Kn = 0.03) so that the phoretic theory in the slip regime ( Kn < 0.1) should apply. The measured capture efficiencies are significantly above the theoretical computations. There is some evidence to suggest that thermophoresis may be underestimated in the computations. This assessment is contigent on attributing the discrepancy between theory and experiment to the theoretical description of phoresis or its application to our experiment.

  5. Evaporation of urea at atmospheric pressure.

    Science.gov (United States)

    Bernhard, Andreas M; Czekaj, Izabela; Elsener, Martin; Wokaun, Alexander; Kröcher, Oliver

    2011-03-31

    Aqueous urea solution is widely used as reducing agent in the selective catalytic reduction of NO(x) (SCR). Because reports of urea vapor at atmospheric pressure are rare, gaseous urea is usually neglected in computational models used for designing SCR systems. In this study, urea evaporation was investigated under flow reactor conditions, and a Fourier transform infrared (FTIR) spectrum of gaseous urea was recorded at atmospheric pressure for the first time. The spectrum was compared to literature data under vacuum conditions and with theoretical spectra of monomolecular and dimeric urea in the gas phase calculated with the density functional theory (DFT) method. Comparison of the spectra indicates that urea vapor is in the monomolecular form at atmospheric pressure. The measured vapor pressure of urea agrees with the thermodynamic data obtained under vacuum reported in the literature. Our results indicate that considering gaseous urea will improve the computational modeling of urea SCR systems.

  6. Prognostic value of the proliferation marker Ki-67 in laryngeal carcinoma : Results of the Accelerated Radiotherapy with Carbogen Breathing and Nicotinamide phase III randomized trial

    NARCIS (Netherlands)

    Rademakers, Saskia E.; Hoogsteen, Ilse J.; Rijken, Paul F.; Terhaard, Chris H.; Doornaert, Patricia A.; Langendijk, Johannes A.; van den Ende, Piet; van der Kogel, Albert J.; Bussink, Johan; Kaanders, Johannes H.

    BackgroundThe prognostic and predictive value of the proliferation marker Ki-67 was investigated in a randomized trial comparing accelerated radiotherapy with carbogen breathing and nicotinamide (ARCON) to accelerated radiotherapy in laryngeal carcinoma. MethodsLabeling index of Ki-67 (Li Ki-67) in

  7. Exact Outage Probability of Dual-Hop CSI-Assisted AF Relaying Over Nakagami-m Fading Channels

    KAUST Repository

    Xia, Minghua

    2012-10-01

    In this correspondence, considering dual-hop channel state information (CSI)-assisted amplify-and-forward (AF) relaying over Nakagami- m fading channels, the cumulative distribution function (CDF) of the end-to-end signal-to-noise ratio (SNR) is derived. In particular, when the fading shape factors m1 and m2 at consecutive hops take non-integer values, the bivariate H-function and G -function are exploited to obtain an exact analytical expression for the CDF. The obtained CDF is then applied to evaluate the outage performance of the system under study. The analytical results of outage probability coincide exactly with Monte-Carlo simulation results and outperform the previously reported upper bounds in the low and medium SNR regions.

  8. Tandem Solar Cells Based on Cu2O and c-Si Subcells in Parallel Configuration: Numerical Simulation

    Directory of Open Access Journals (Sweden)

    Mihai Răzvan Mitroi

    2017-01-01

    Full Text Available A tandem solar cell consisting of a bottom c-Si high-efficiency subcell and a top low-cost Cu2O subcell in parallel configuration is evaluated for the first time by a use of an electrical model. A numerical simulation based on the single-diode model of the solar cell is performed. The numerical method determines both the model parameters and the parameters of the subcells and tandem from the maximization of output power. The simulations indicate a theoretical limit value of the tandem power conversion efficiency of 31.23% at 298 K. The influence of temperature on the maximum output power is analyzed. This tandem configuration allows a great potential for the development of a new generation of low-cost high-efficiency solar cells.

  9. Effectiveness of the KiVa Antibullying Program: Grades 1-3 and 7-9

    NARCIS (Netherlands)

    Kärnä, A.; Voeten, M.J.M.; Little, T.D.; Alanen, E.; Poskiparta, E.H.; Salmivalli, C.

    2013-01-01

    This study investigated the effectiveness of the KiVa Antibullying Program in two samples of students, one from Grades 1-3 (7-9 years old, N = 6,927) and the other from Grades 7-9 (13-15 years old, N = 16, 503). The Grades 1-3 students were located in 74 schools and Grades 7-9 students in 73 schools

  10. Poly(ethylene oxide) complexed with KI: An x-ray absorption study

    Energy Technology Data Exchange (ETDEWEB)

    Yang, X.Q.; Chen, J.; Skotheim, T.A.; Okamoto, Y.; denBoer, M.L. (Brookhaven National Lab., Upton, NY (USA); Polytechnic Univ., Brooklyn, NY (USA); Hunter Coll., New York, NY (USA))

    1989-01-01

    Polymer-salt complexes of poly(ethylene oxide) (PEO) and KI have been studied with the technique of Near Edge X-ray Absorption Fine Structure of the K-edge of potassium. The changes observed in the spectra as a function of temperature are compared with model systems. The results suggests that the oxygen complexation of the potassium ion is reduced at elevated temperatures. 7 refs., 2 figs.

  11. Euro tulekust lahutab 1,5 miljardit ülejääki / Raimo Poom

    Index Scriptorium Estoniae

    Poom, Raimo

    2010-01-01

    2009. aasta III kvartali lõpus oli Eesti eelarvedefitsiit 4,9% SKT-st, eelarve ülejääk oli III kvartalis 1,4 mld. Rahandusministeeriumi nõunik Sven Kirsipuu on arvamusel, et ka IV kvartal peaks olema ülejäägiga. Euroalaga liitumiseks on vaja vähemalt 1,5-miljardilist ülejääki. Graafikud

  12. Immunohistochemical characterization of molecular classification of breast carcinoma and its relation with Ki-67

    OpenAIRE

    Shabnam Karangadan; Anuradha Ganesh Patil; Sainath Karnappa Andola

    2016-01-01

    Background: Breast carcinoma is the leading cause of cancer deaths in women. Molecular classification of breast carcinoma along with Ki-67 index is considered a better predictive factor for prognosis and treatment than routine histopathology. Aims: To classify breast carcinoma into the four molecular subtypes defined by immunohistochemical expression of triple markers: Luminal A (estrogen receptor/progesterone receptor-positive [ER/PR+] and human epidermal growth factor receptor 2 HER2/neu), ...

  13. The significance of immunohistochemical expression of merlin, Ki-67, and p53 in meningiomas.

    Science.gov (United States)

    Pavelin, Sanda; Bečić, Kristijan; Forempoher, Gea; Tomić, Snježana; Capkun, Vesna; Drmić-Hofman, Irena; Mrklić, Ivana; Lušić, Ivo; Pogorelić, Zenon

    2014-01-01

    Meningiomas are one of the most common CNS tumors whose appearance is closely linked to NF2 gene product merlin. Tumor markers Ki-67 and p53 play established role in tumor progression which should be analyzed in close association with merlin expression. The aim of this study was to investigate the immunohistochemical expression of merlin in meningiomas, correlation with Ki-67 and p53, and to determine the association of these results with histologic grade and subtype. The histologic sections of 170 patients with totally resected meningiomas, between January 2000 and December 2010, were classified according to WHO, immunohistochemically stained for Ki-67, p53, and merlin, and analyzed using light microscope. Ki-67 median was 5.6 times higher in group of patients with negative merlin than in those with positive merlin (P=0.05). Statistically significant correlation of merlin with p53 was found (PMerlin expression between 2 combined groups (meningothelial/secretory and fibroblastic/transitional) was statistically significant (P=0.002). By comparing merlin expression and p53 levels, statistically significant difference was found (P=0.017). In the group with positive merlin and negative p53 as well as positive merlin and low p53, meningothelial/secretory subtypes of meningiomas were more common. In combination of negative merlin and negative p53 as well as negative merlin and high p53, there were more meningiomas of fibroblastic/transitional subtype. There was no statistically significant correlation between merlin and tumor grade (P=0.420). There is undeniable influence of merlin on the development and the proliferative ability of meningioma subtypes. Significant role of p53 pathway was confirmed.

  14. Expression of Ki-67 (MIB-1) and GLUT-1 proteins in non-advanced prostatic cancer.

    Science.gov (United States)

    Luczynska, Elzbieta; Gasinska, Anna; Wilk, Waclaw

    2012-12-01

    The expression of Ki-67 (MIB-1) and glucose transporter-1 (GLUT-1) were evaluated in patients with clinically localized prostate cancer (PC) who had undergone radical prostatectomy with curative intent. 140 low advanced PC specimens were studied. Protein expression was assessed immunohistochemically on tumour sections and expressed as a labelling index, i.e. the percentage of positively stained cells. In the case of Ki-67 nuclear staining and in the case of GLUT-1 membrane and cytoplasmic staining was considered as positive. The patients' mean age was 62.9 ±6.2 years. There were 13 (9.3%) at pTNM stage 1, 78 (55.7%) at stage 2, 40 (28.6%) at stage 3 and 9 (6.4%) at stage 4, respectively. 75 (53.6%) tumours were well differentiated (Gleason score ≤6), 52 (37.1%) moderately differentiated (Gleason score of 7) and 13 (9.3%) poorly differentiated (Gleason score 8-10). The mean pre-operative serum PSA was 9.9 ± SE 0.5 ng/ml, and the mean LI was equal to 8.1 ±0.6% and 29.7 ±2.0%, for MIB-1 and GLUT-1, respectively. Increase of pathological tumor volume and tumor grade was associated with statistically significant growth of PSA (p GLUT-1 LI the relation was not significant. Ki-67 expression was correlated with PSA levels (p = 0.013) and GLUT-1 scores (p = 0.04). In PC, an increase in the proliferation rate (higher MIB-1LI) in higher pTNM stages and tumour grades may point to Ki-67 as a good marker of biological aggressiveness useful in selecting patients for more aggressive treatment. A correlation between proliferation and GLUT-1 score may be the evidence of active glycolytic metabolism in hypoxic regions.

  15. Screening for cervical cancer precursors with p16/Ki-67 dual-stained cytology

    DEFF Research Database (Denmark)

    Ikenberg, Hans; Bergeron, Christine; Schmidt, Dietmar

    2013-01-01

    Pap cytology is known to be more specific but less sensitive than testing for human papillomavirus (HPV) for the detection of high-grade cervical intraepithelial neoplasia (CIN2+). We assessed whether p16/Ki-67 dual-stained cytology, a biomarker combination indicative of transforming HPV infections......, can provide high sensitivity for CIN2+ in screening while maintaining high specificity. Results were compared with Pap cytology and HPV testing....

  16. Strong lens search in the ESO public Survey KiDS

    NARCIS (Netherlands)

    Napolitano, N. R.; Covone, G.; Roy, N.; Tortora, C.; Barbera, F. La; Radovich, M.; Getman, F.; Capaccioli, M.; Colonna, A.; Paolillo, M.; Kleijn, G. A. Verdoes; Koopmans, L. V. E.; Valentijn, E; Napolitano, Nicola R.; Longo, Giuseppe; Marconi, Marcella; Paolillo, Maurizio; Lodice, Enrichetta

    2015-01-01

    We have started a systematic search for strong lens candidates in the ESO public survey KiDS based on the visual inspection of massive galaxies in the redshift range 0. 1 < z < 0. 5. As a pilot program we have inspected 100 deg2, which overlap with SDSS and where there are known lenses to use as a

  17. THE CENTRAL SENSITIZATION INVENTORY (CSI): ESTABLISHING CLINICALLY-SIGNIFICANT VALUES FOR IDENTIFYING CENTRAL SENSITIVITY SYNDROMES IN AN OUTPATIENT CHRONIC PAIN SAMPLE

    Science.gov (United States)

    Neblett, Randy; Cohen, Howard; Choi, Yunhee; Hartzell, Meredith; Williams, Mark; Mayer, Tom G.; Gatchel, Robert J.

    2013-01-01

    Central Sensitization (CS) is a proposed physiological phenomenon in which central nervous system neurons become hyper-excitable, resulting in hypersensitivity to both noxious and non-noxious stimuli. The term Central Sensitivity Syndrome (CSS) describes a group of medically-indistinct (or nonspecific) disorders, such as fibromyalgia, chronic fatigue, and irritable bowel, for which CS may be a common etiology. In a previous study, the Central Sensitization Inventory (CSI) was introduced as a screening instrument for clinicians to help identify patients with a CSS. It was found to have high reliability and validity (test-retest reliability = 0.82; Cronbach’s alpha = 0.88). The present study investigated a cohort of 121 patients who were referred to a multidisciplinary pain center, which specialized in the assessment and treatment of complex pain and psychophysiological disorders, including CSSs. A large percentage of patients (n = 89, 74%) met clinical criteria for one or more CSSs, and CSI scores were positively correlated with the number of diagnosed CSSs. A Receiver Operating Characteristic (ROC) analysis determined that a CSI score of 40 out of 100 best distinguished between the CSS patient group and a non-patient comparison sample (n = 129) (AUC= 0.86, Sensitivity = 81%, Specicifity = 75%). PERSPECTIVE The Central Sensitization Inventory (CSI) is a new self-report screening instrument to help identify patients with Central Sensitivity Syndromes, including fibromyalgia. The present study investigated CSI scores in a heterogeneous pain population, with a large percentage of CSSs, and a normative non-clinical sample, to determine a clinically-relevant cutoff value. PMID:23490634

  18. Diffusion of Na(I), Cs(I), Sr(II) and Eu(III) in smectite rich natural clay.

    Science.gov (United States)

    Kasar, Sharayu; Kumar, Sumit; Bajpai, R K; Tomar, B S

    2016-01-01

    Diffusion of Na(I), Cs(I), Sr(II) and Eu(III) in smectite rich natural clay, proposed as a backfill material in the Indian geological repository, was studied using the out-diffusion method. Radiotracers (22)Na, (137)Cs, (85)Sr and (154)Eu were used; the first three are carrier-free enabling experimental work at sub-micromolar metal ion concentration, and Eu(III) tracer (154)Eu was used at sub millimolar concentration. An out-diffusion methodology, wherein a thin planar source of radioactivity placed between two clay columns diffuses out, was used to obtain the apparent diffusion coefficient (Da) values. This methodology enabled determination of diffusion coefficient even for strongly sorbing (154)Eu. Da values for (22)Na, (137)Cs, (85)Sr and (154)Eu were 2.35 (±0.14) × 10(-11), 2.65 (±0.09) × 10(-12), 3.32 (±0.15) × 10(-11) and 1.23 (±0.15) × 10(-13) m(2) s(-1), respectively. Da values were found to be in fair agreement with literature data reported for similar mineralogical sediments. Sorption of radionuclides on the clay was also determined in the present study and differences in Da values were rationalized on the basis of sorption data. Distribution ratios (Kd) for Cs(I) and Eu(III) were higher than that for Sr(II), which in turn was higher than that for Na(I). Copyright © 2015 Elsevier Ltd. All rights reserved.

  19. Spatial variability and changes of metabolite concentrations in the cortico-spinal tract in multiple sclerosis using coronal CSI.

    Science.gov (United States)

    Tur, Carmen; Wheeler-Kingshott, Claudia A M; Altmann, Daniel R; Miller, David H; Thompson, Alan J; Ciccarelli, Olga

    2014-03-01

    We characterized metabolic changes along the cortico-spinal tract (CST) in multiple sclerosis (MS) patients using a novel application of chemical shift imaging (CSI) and considering the spatial variation of metabolite levels. Thirteen relapsing-remitting (RR) and 13 primary-progressive (PP) MS patients and 16 controls underwent (1)H-MR CSI, which was applied to coronal-oblique scans to sample the entire CST. The concentrations of the main metabolites, i.e., N-acetyl-aspartate, myo-Inositol (Ins), choline containing compounds (Cho) and creatine and phosphocreatine (Cr), were calculated within voxels placed in regions where the CST is located, from cerebral peduncle to corona radiata. Differences in metabolite concentrations between groups and associations between metabolite concentrations and disability were investigated, allowing for the spatial variability of metabolite concentrations in the statistical model. RRMS patients showed higher CST Cho concentration than controls, and higher CST Ins concentration than PPMS, suggesting greater inflammation and glial proliferation in the RR than in the PP course. In RRMS, a significant, albeit modest, association between greater Ins concentration and greater disability suggested that gliosis may be relevant to disability. In PPMS, lower CST Cho and Cr concentrations correlated with greater disability, suggesting that in the progressive stage of the disease, inflammation declines and energy metabolism reduces. Attention to the spatial variation of metabolite concentrations made it possible to detect in patients a greater increase in Cr concentration towards the superior voxels as compared to controls and a stronger association between Cho and disability, suggesting that this step improves our ability to identify clinically relevant metabolic changes. Copyright © 2012 Wiley Periodicals, Inc.

  20. FEASIBILITY STUDY FOR POTASSIUM IODIDE (KI) DISTRIBUTION IN NEW YORK CITY.

    Energy Technology Data Exchange (ETDEWEB)

    MOSS, STEVEN

    2005-04-29

    The New York City Department of Health and Mental Hygiene (DOHMH), Bureau of Environmental Science and Engineering, Office of Radiological Health (ORH) [as the primary local technical consultant in the event of a radiological or nuclear incident within the boundaries of New York City] requested the assistance of Brookhaven National Laboratory (BNL) with the development of a Feasibility Study for Potassium Iodide (KI) distribution in the unlikely event of a significant release of radioactive iodine in or near New York City. Brookhaven National Laboratory had previously provided support for New York City with the development of the radiological/nuclear portions of its All Hazards Emergency Response Plans. The work is funded by Medical and Health Research Association (MHRA) of New York City, Inc., under a work grant by the Federal Centers for Disease Control (CDC) for Public Health Preparedness and Response for Bioterrorism. This report is part of the result of that effort. The conclusions of this report are that: (1) There is no credible radiological scenario that would prompt the need for large segments of the general population of New York City to take KI as a result of a projected plume exposure to radioiodine reaching even the lowest threshold of 5 rem to the thyroid; and (2) KI should be stockpiled in amounts and locations sufficient for use by first responders/emergency responders in response to any localized release of radioiodine.

  1. KiSS-1 and GPR54 as new players in gonadotropin regulation and puberty.

    Science.gov (United States)

    Kaiser, Ursula B; Kuohung, Wendy

    2005-04-01

    The recent identification of loss-of-function mutations in the gene encoding GPR54, the receptor for the KiSS-1-derived peptides, kisspeptins, has highlighted a previously unrecognized pathway in the physiologic regulation of puberty and reproduction. Patients with loss-of-function mutations in GPR54 have idiopathic hypogonadotropic hypogonadism, and mice lacking GPR54 similarly fail to undergo puberty and have immature reproductive organs and low levels of sex steroids and gonadotropins. These observations have led to the hypothesis that kisspeptins activate hypothalamic GnRH release, thereby serving as a pivotal factor in the pubertal activation of the reproductive cascade. This hypothesis is supported by subsequent studies in rodent and primate models that have demonstrated localization of KiSS-1 mRNA in the hypothalamus, colocalization of GPR54 in GnRH neurons, GnRH-dependent activation of LH and FSH release by intracerebroventricular or peripheral administration of kisspeptin, and increased hypothalamic KiSS-1 and GPR54 mRNA levels at the onset of puberty. Taken together, these findings weave a compelling case for a role of the kisspeptin-GPR54 system in the activation of GnRH neurons at the time of pubertal awakening of the reproductive axis.

  2. GPR54 and KiSS-1: role in the regulation of puberty and reproduction.

    Science.gov (United States)

    Kuohung, Wendy; Kaiser, Ursula B

    2006-12-01

    The finding of inactivating mutations in GPR54 in IHH patients and the lack of reproductive maturation of the GPR54 null mouse have uncovered a previously unrecognized role for GPR54 and KiSS-1 in the physiologic regulation of puberty and reproduction. This newly identified function for GPR54 and its cognate ligand, kisspeptin, has led to additional studies that have localized GPR54 and KiSS-1 mRNA in the hypothalamus, colocalized GPR54 in GnRH neurons, demonstrated GnRH-dependent activation of LH and FSH release by kisspeptin, and shown increased hypothalamic KiSS-1 and GPR54 mRNA levels at the time of puberty. Taken together, these findings establish the role of the kisspeptin-GPR54 system in the stimulation of GnRH neurons during puberty. The mechanisms by which kisspeptin activates GnRH release, as well as the trigger for this pathway at the onset of puberty, are yet to be elucidated. In the future, modulators of GPR54 activity, including kisspeptin, may prove valuable in clinical applications in the fields of both cancer therapy and reproductive medicine.

  3. KiDS-450: tomographic cross-correlation of galaxy shear with Planck lensing

    Science.gov (United States)

    Harnois-Déraps, Joachim; Tröster, Tilman; Chisari, Nora Elisa; Heymans, Catherine; van Waerbeke, Ludovic; Asgari, Marika; Bilicki, Maciej; Choi, Ami; Erben, Thomas; Hildebrandt, Hendrik; Hoekstra, Henk; Joudaki, Shahab; Kuijken, Konrad; Merten, Julian; Miller, Lance; Robertson, Naomi; Schneider, Peter; Viola, Massimo

    2017-10-01

    We present the tomographic cross-correlation between galaxy lensing measured in the Kilo Degree Survey (KiDS-450) with overlapping lensing measurements of the cosmic microwave background (CMB), as detected by Planck 2015. We compare our joint probe measurement to the theoretical expectation for a flat Λ cold dark matter cosmology, assuming the best-fitting cosmological parameters from the KiDS-450 cosmic shear and Planck CMB analyses. We find that our results are consistent within 1σ with the KiDS-450 cosmology, with an amplitude re-scaling parameter AKiDS = 0.86 ± 0.19. Adopting a Planck cosmology, we find our results are consistent within 2σ, with APlanck = 0.68 ± 0.15. We show that the agreement is improved in both cases when the contamination to the signal by intrinsic galaxy alignments is accounted for, increasing A by ∼0.1. This is the first tomographic analysis of the galaxy lensing - CMB lensing cross-correlation signal, and is based on five photometric redshift bins. We use this measurement as an independent validation of the multiplicative shear calibration and of the calibrated source redshift distribution at high redshifts. We find that constraints on these two quantities are strongly correlated when obtained from this technique, which should therefore not be considered as a stand-alone competitive calibration tool.

  4. Analysis of the Ki-67 index in the vaginal epithelium of castrated rats treated with tamoxifen

    Science.gov (United States)

    Nery-Aguiar, Afif Rieth; Aguiar, Yousef Qathaf; Júnior, Airton Mendes Conde; Alencar, Airlane Pereira; Tavares, Cleciton Braga; Lopes-Costa, Pedro Vitor; Nazário, Afonso Celso; da Silva, Benedito Borges

    2016-01-01

    OBJECTIVES: Vaginal atrophy and breast cancer are common conditions in postmenopausal women and tamoxifen is the standard endocrine treatment for hormone-sensitive tumors. The present study aimed to assess the effect of tamoxifen on Ki-67 protein expression in the vaginal epithelium of castrated rats. MATERIAL AND METHODS: Forty Wistar-Hannover adult, virgin, castrated rats were randomly divided into two groups, group I (control, n=20) and group II (tamoxifen, n=20), receiving 0.5 ml of propylene glycol and 250 µg of tamoxifen diluted in 0.5 ml of propylene glycol, respectively, daily by gavage for 30 days. On the 31st day, the rats were euthanized and their vaginas were removed and fixed in 10% buffered formalin for the immunohistochemical study of Ki-67 protein expression. Data were analyzed by the Levene and Student's t tests (pvagina of groups I and II was 4.04±0.96 and 26.86±2.19, respectively (p<0.001). CONCLUSIONS: According to the results of the present study, tamoxifen, at the dose and treatment length used, induced a significant increase in the cell proliferation of the vaginal mucosa in castrated rats, as evaluated by Ki-67 protein expression. PMID:26934238

  5. Endometrial cytopathology. An image analysis approach using the Ki-67 biomarker.

    Science.gov (United States)

    Apostolou, G; Apostolou, N; Moulos, P; Chatzipantelis, P

    2017-10-01

    To investigate the different identity and biological behaviour of endometrial benign epithelial and endometrial adenocarcinoma cell categories. For this study, the imprint smears from three groups, 10 cases of disordered proliferative/benign hyperplastic endometrium, 21 cases of low-grade and eight cases of high-grade endometrial adenocarcinoma, were examined using image analysis and the Ki-67 biomarker. The plastic stem cell model was also applied. Among the examined groups, the nuclear area major axis ranged statistically different in the digitally measured Ki-67 positive endometrial epithelial and adenocarcinoma cells (Pendometrial adenocarcinomas (Pendometrial lesions, and a relatively stable pathway was noticed in low- and high-grade endometrial adenocarcinomas. The different range of the nuclear area major axis among cycling endometrial epithelial and adenocarcinoma cells may correlate with their specific identity and biological behaviour. The different values of the cycling nuclear area major dimension may also be connected with the biological behaviour of the three examined groups. Moreover, the endometrial epithelial cells may follow a Ki-67 increase pathway, instead of the relatively stable pathway which the rapidly proliferating adenocarcinoma cells may use. Finally, the studied cell categories may exhibit different biology, because their stem cells may reside in different states of stemness. © 2017 John Wiley & Sons Ltd.

  6. Numerical study of the evaporation process and parameter estimation analysis of an evaporation experiment

    Directory of Open Access Journals (Sweden)

    K. Schneider-Zapp

    2010-05-01

    Full Text Available Evaporation is an important process in soil-atmosphere interaction. The determination of hydraulic properties is one of the crucial parts in the simulation of water transport in porous media. Schneider et al. (2006 developed a new evaporation method to improve the estimation of hydraulic properties in the dry range. In this study we used numerical simulations of the experiment to study the physical dynamics in more detail, to optimise the boundary conditions and to choose the optimal combination of measurements. The physical analysis exposed, in accordance to experimental findings in the literature, two different evaporation regimes: (i a soil-atmosphere boundary layer dominated regime (regime I close to saturation and (ii a hydraulically dominated regime (regime II. During this second regime a drying front (interface between unsaturated and dry zone with very steep gradients forms which penetrates deeper into the soil as time passes. The sensitivity analysis showed that the result is especially sensitive at the transition between the two regimes. By changing the boundary conditions it is possible to force the system to switch between the two regimes, e.g. from II back to I. Based on this findings a multistep experiment was developed. The response surfaces for all parameter combinations are flat and have a unique, localised minimum. Best parameter estimates are obtained if the evaporation flux and a potential measurement in 2 cm depth are used as target variables. Parameter estimation from simulated experiments with realistic measurement errors with a two-stage Monte-Carlo Levenberg-Marquardt procedure and manual rejection of obvious misfits lead to acceptable results for three different soil textures.

  7. Increasing the Efficiency of Maple Sap Evaporators with Heat Exchangers

    Science.gov (United States)

    Lawrence D. Garrett; Howard Duchacek; Mariafranca Morselli; Frederick M. Laing; Neil K. Huyler; James W. Marvin

    1977-01-01

    A study of the engineering and economic effects of heat exchangers in conventional maple syrup evaporators indicated that: (1) Efficiency was increased by 15 to 17 percent with heat exchangers; (2) Syrup produced in evaporators with heat exchangers was similar to syrup produced in conventional systems in flavor and in chemical and physical composition; and (3) Heat...

  8. Impacts of Salinity on Soil Hydraulic Properties and Evaporation Fluxes

    Science.gov (United States)

    Fierro, V.; Cristi Matte, F.; Suarez, F. I.; Munoz, J. F.

    2014-12-01

    Saline soils are common in arid zones, where evaporation from shallow groundwater is generally the main component of the water balance. Thus, to correctly manage water resources in these zones, it is important to quantify the evaporation fluxes. Evaporation from saline soils is a complex process that couples the movement of salts, heat, liquid water and water vapor, and strongly depends on the soil water content. Precipitation/dissolution reactions can change the soil structure and alter flow paths, modifying evaporation fluxes. We utilized the HYDRUS-1D model to investigate the effects of salinity on soil hydraulic properties and evaporation fluxes. HYDRUS-1D simulates the transport of liquid water, water vapor, and heat, and can incorporate precipitation/dissolution reactions of the major ions. To run the model, we determined the water retention curve for a soil with different salinities; and we used meteorological forcing from an experimental site from the Atacama Desert. It was found that higher sodium adsorption ratios in the soil increase the soil water retention capacity. Also, it was found that evaporation fluxes increase salts concentration near the soil surface, changing the soil's water retention capacity in that zone. Finally, movement of salts causes differences in evaporation fluxes. It is thus necessary to incorporate salt precipitation/dissolution reactions and its effects on the water retention curve to correctly simulate evaporation in saline soils

  9. Modeling Coupled Evaporation and Seepage in Ventilated Cavities

    Energy Technology Data Exchange (ETDEWEB)

    T. Ghezzehei; R. Trautz; S. Finsterle; P. Cook; C. Ahlers

    2004-07-01

    Cavities excavated in unsaturated geological formations are important to activities such as nuclear waste disposal and mining. Such cavities provide a unique setting for simultaneous occurrence of seepage and evaporation. Previously, inverse numerical modeling of field liquid-release tests and associated seepage into cavities were used to provide seepage-related large-scale formation properties by ignoring the impact of evaporation. The applicability of such models was limited to the narrow range of ventilation conditions under which the models were calibrated. The objective of this study was to alleviate this limitation by incorporating evaporation into the seepage models. We modeled evaporation as an isothermal vapor diffusion process. The semi-physical model accounts for the relative humidity, temperature, and ventilation conditions of the cavities. The evaporation boundary layer thickness (BLT) over which diffusion occurs was estimated by calibration against free-water evaporation data collected inside the experimental cavities. The estimated values of BLT were 5 to 7 mm for the open underground drifts and 20 mm for niches closed off by bulkheads. Compared to previous models that neglected the effect of evaporation, this new approach showed significant improvement in capturing seepage fluctuations into open cavities of low relative humidity. At high relative-humidity values (greater than 85%), the effect of evaporation on seepage was very small.

  10. 7 CFR 58.937 - Physical requirements for evaporated milk.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Physical requirements for evaporated milk. 58.937... requirements for evaporated milk. (a) Flavor. The product shall possess a sweet, pleasing and desirable flavor... objectionable tastes and odors. (b) Body and texture. The product shall be of uniform consistency and appearance...

  11. Potential for natural evaporation as a reliable renewable energy resource.

    Science.gov (United States)

    Cavusoglu, Ahmet-Hamdi; Chen, Xi; Gentine, Pierre; Sahin, Ozgur

    2017-09-26

    About 50% of the solar energy absorbed at the Earth's surface drives evaporation, fueling the water cycle that affects various renewable energy resources, such as wind and hydropower. Recent advances demonstrate our nascent ability to convert evaporation energy into work, yet there is little understanding about the potential of this resource. Here we study the energy available from natural evaporation to predict the potential of this ubiquitous resource. We find that natural evaporation from open water surfaces could provide power densities comparable to current wind and solar technologies while cutting evaporative water losses by nearly half. We estimate up to 325 GW of power is potentially available in the United States. Strikingly, water's large heat capacity is sufficient to control power output by storing excess energy when demand is low, thus reducing intermittency and improving reliability. Our findings motivate the improvement of materials and devices that convert energy from evaporation.The evaporation of water represents an alternative source of renewable energy. Building on previous models of evaporation, Cavusoglu et al. show that the power available from this natural resource is comparable to wind and solar power, yet it does not suffer as much from varying weather conditions.

  12. Studies on tin oxide films prepared by electron beam evaporation ...

    Indian Academy of Sciences (India)

    Transparent conducting tin oxide thin films have been prepared by electron beam evaporation and spray pyrolysis methods. Structural, optical and electrical properties were studied under different preparation conditions like substrate temperature, solution flow rate and rate of deposition. Resistivity of undoped evaporated ...

  13. Water storage and evaporation as constituents of rainfall interception

    NARCIS (Netherlands)

    Klaassen, W; Bosveld, F; de Water, E

    1998-01-01

    Intercepted rainfall may be evaporated during or after the rain event. Intercepted rain is generally determined as the difference between rainfall measurements outside and inside the forest. Such measurements are often used to discriminate between water storage and evaporation during rain as well.

  14. Droplet Evaporator For High-Capacity Heat Transfer

    Science.gov (United States)

    Valenzuela, Javier A.

    1993-01-01

    Proposed heat-exchange scheme boosts heat transfer per unit area. Key component is generator that fires uniform size droplets of subcooled liquid at hot plate. On impact, droplets spread out and evaporate almost instantly, removing heat from plate. In practice, many generator nozzles arrayed over evaporator plate.

  15. 40 CFR 86.1243-96 - Calculations; evaporative emissions.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 19 2010-07-01 2010-07-01 false Calculations; evaporative emissions... Petroleum Gas-Fueled and Methanol-Fueled Heavy-Duty Vehicles § 86.1243-96 Calculations; evaporative... equations can be used in integral form. (i) Methanol emissions: ER06OC93.133 Where, (A) MCH 3 OH=methanol...

  16. 40 CFR 86.143-96 - Calculations; evaporative emissions.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 18 2010-07-01 2010-07-01 false Calculations; evaporative emissions... Complete Heavy-Duty Vehicles; Test Procedures § 86.143-96 Calculations; evaporative emissions. (a) The... can be used in integral form. (i) Methanol emissions: MCH 3 OH=ρCH 3 OH Vmix× (CCH 3 OH, rl−CCH 3 OH...

  17. Nonlinear Superheat and Evaporation Temperature Control of a Refrigeration Plant

    DEFF Research Database (Denmark)

    Rasmussen, Henrik; Thybo, Claus; Larsen, Lars F. S.

    2006-01-01

    This paper proposes novel control of the superheat of the evaporator in a refrigeration system. A new model of the evaporator is developed and based on this model the superheat is transferred to a referred variable. It is shown that control of this variable leads to a linear system independent...

  18. A phylogenetic approach to total evaporative water loss in mammals.

    Science.gov (United States)

    Van Sant, Matthew J; Oufiero, Christopher E; Muñoz-Garcia, Agustí; Hammond, Kimberly A; Williams, Joseph B

    2012-01-01

    Maintaining appropriate water balance is a constant challenge for terrestrial mammals, and this problem can be exacerbated in desiccating environments. It has been proposed that natural selection has provided desert-dwelling mammals physiological mechanisms to reduce rates of total evaporative water loss. In this study, we evaluated the relationship between total evaporative water loss and body mass in mammals by using a recent phylogenetic hypothesis. We compared total evaporative water loss in 80 species of arid-zone mammals to that in 56 species that inhabit mesic regions, ranging in size from 4 g to 3,500 kg, to test the hypothesis that mammals from arid environments have lower rates of total evaporative water loss than mammals from mesic environments once phylogeny is taken into account. We found that arid species had lower rates of total evaporative water loss than mesic species when using a dichotomous variable to describe habitat (arid or mesic). We also found that total evaporative water loss was negatively correlated with the average maximum and minimum environmental temperature as well as the maximum vapor pressure deficit of the environment. Annual precipitation and the variable Q (a measure of habitat aridity) were positively correlated with total evaporative water loss. These results support the hypothesis that desert-dwelling mammals have lower rates of total evaporative water loss than mesic species after controlling for body mass and evolutionary relatedness regardless of whether categorical or continuous variables are used to describe habitat.

  19. Evaporation Dynamics of Moss and Bare Soil in Boreal Forests

    Science.gov (United States)

    Dempster, S.; Young, J. M.; Barron, C. G.; Bolton, W. R.

    2013-12-01

    Evaporation dynamics of mosses is a critical process in boreal and arctic systems and represents a key uncertainty in hydrology and climate models. At this point, moss evaporation is not well quantified at the plot or landscape scale. Relative to bare soil or litter evaporation, moss evaporation can be challenging to predict because the water flux is not isolated to the moss surface. Evaporation can originate from nearly 10 cm below the surface. Some mosses can wick moisture from even deeper than 10 cm, which subsequently evaporates. The goal of this study was to use field measurements to quantify the moss evaporation dynamics in a coniferous forest relative to bare ground or litter evaporation dynamics in a deciduous forest in Interior Alaska. Measurements were made in two ecosystem types within the boreal forest of Interior Alaska: a deciduous forest devoid of moss and a coniferous forest with a thick moss layer. A small clear chamber was attached to a LiCor 840 infrared gas analyzer in a closed loop system with a low flow rate. Water fluxes were measured for ~ 90 seconds on each plot in dry and wet soil and moss conditions. Additional measurements included: soil temperature, soil moisture, air temperature, barometric pressure, dew point, relative humidity, and wind speed. Thermal infrared images were also captured in congruence with water flux measurements to determine skin temperature. We found that the moss evaporation rate was over 100% greater than the soil evaporation rate (0.057 g/min vs. 0.024 g/min), and evaporation rates in both systems were most strongly driven by relative humidity and surface temperature. Surface temperature was lower at the birch site than the black spruce site because trees shade the surface beneath the birch. High fluxes associated with high water content were sustained for a longer period of time over the mosses compared to the bare soil. The thermal IR data showed that skin temperature lagged the evaporation flux, such that the

  20. Computational Fluid Dynamics Analysis of an Evaporative Cooling System

    Directory of Open Access Journals (Sweden)

    Kapilan N.

    2016-11-01

    Full Text Available The use of chlorofluorocarbon based refrigerants in the air-conditioning system increases the global warming and causes the climate change. The climate change is expected to present a number of challenges for the built environment and an evaporative cooling system is one of the simplest and environmentally friendly cooling system. The evaporative cooling system is most widely used in summer and in rural and urban areas of India for human comfort. In evaporative cooling system, the addition of water into air reduces the temperature of the air as the energy needed to evaporate the water is taken from the air. Computational fluid dynamics is a numerical analysis and was used to analyse the evaporative cooling system. The CFD results are matches with the experimental results.

  1. Simulations of dynamic resistive evaporation in a vacuum

    Science.gov (United States)

    Kazanskiy, N. L.; Kolpakov, V. A.; Krichevskiy, S. V.; Podlipnov, V. V.

    2017-10-01

    The model of dynamic resistive evaporation in vacuum has been considered, and the model takes into account the structural peculiarities of the corresponding evaporator. In the model, the dependences to determine the time of material heating up to evaporation temperature as well as dynamic characteristics of the evaporation have been obtained. It has been shown that the obtained characteristics are nonharmonic and periodically repeated. The adequacy of the developed model to the physical model has been corroborated. It has been found that the discrepancy between the experimental and calculated time characteristics of shutter movement is not higher than 5%. The recommendations for using the suggested model to fabricate of thin films of multicomponent materials via thermal evaporation have been considered.

  2. Synthesis H-Zeolite catalyst by impregnation KI/KIO3 and performance test catalyst for biodiesel production

    Science.gov (United States)

    Widayat, W.; Rizky Wicaksono, Adit; Hakim Firdaus, Lukman; Okvitarini, Ndaru

    2016-02-01

    The objective of this research is to produce H-catalyst catalyst that was impregnated with KI/KIO3. The catalyst was analyzed about surface area, X-Ray Diffraction (XRD) and performance test of catalyst for biodiesel production. An H-Zeolite catalyst was synthesized from natural zeolite with chemical treatment processing, impregnation KI/KIO3 and physical treatment. The results shows that the surface area of the catalyst by 27.236 m2/g at a concentration of 5% KI. XRD analysis shows peak 2-θ at 23.627o indicating that KI was impregnated on H-zeolite catalyst. The catalyst was tested in production of biodiesel using palm oil with conventional methods for 3 hour at temperature of 70-80 oC. The result for conversion Fatty Acid Methyl Ester (FAME) reached maximum value on 87.91% under production process using catalyst 5% KIO3-H zeolite.

  3. KiVa Antibullying Program: Overview of Evaluation Studies Based on a Randomized Controlled Trial and National Rollout in Finland

    Directory of Open Access Journals (Sweden)

    Christina Salmivalli

    2012-12-01

    Full Text Available The effects of a Finnish national school-based antibullying program (KiVa were evaluated in a randomized controlled trial (2007–2009 and during nationwide implementation (since 2009. The KiVa program is been found to reduce bullying and victimization and increase empathy towards victimized peers and self-efficacy to support and defend them. KiVa increases school liking and motivation and contributes to significant reductions in anxiety, depression, and negative peer perceptions. Somewhat larger reductions in bullying and victimization were found in the randomized controlled trial than in the broad rollout, and the largest effects were obtained in primary school (grades 1–6. The uptake of the KiVa program is remarkable, with 90 percent of Finnish comprehensive schools currently registered as program users.

  4. Ban Ki-moon Caves to "Immense" Pressure, Drops Israel From U.N. "List of Shame"

    National Research Council Canada - National Science Library

    Jonathan Cook

    2015-01-01

      UN Secretary-General Ban Ki-moon has overruled his own officials' recommendation that Israel be included on this year's UN "list of shame," which identifies the gravest violators of children's rights...

  5. Complex Effects of Salinity on Water Evaporation From Porous Media.

    Science.gov (United States)

    Shokri-Kuehni, S. M. S.; Webb, C.; Shokri, N.

    2016-12-01

    Saline water evaporation from porous media is influenced by transport properties of porous media, properties of the evaporating solution and external conditions. In this work, we investigated the effects of salt concentration on the drying behaviour of a porous medium and its surface temperature. Our key focus was about how the precipitated salt forming at the surface of drying porous media influences the evaporation rate. To do so, a series of evaporation experiments were conducted using columns packed with sand particles saturated with NaCl solutions of varying concentrations. The columns were placed on digital balances to record the evaporation dynamics and were exposed to metal halide lamps to boost the evaporation. A FLIR thermal camera was fixed above the sand columns to record the surface temperature. Additional experiments were conducted using sand packs saturated with salty water in the presence of water table at well-defined depths using Mariotte flasks. We could delineate the effects of salt concentration and crust formation on the general dynamics of the evaporation process (at different salt concentrations). Microscopic analysis of precipitated salt at the surface revealed the complex dynamics of salt evolution at the surface and its consequences on the evaporation behaviour. Our results suggest that the presence of porous salt at the surface causes top-supplied creeping of the solution feeding the growth of subsequent precipitation. This causes appearance and disappearance of cold-spots at the surface of porous media brought about by crust formation and preferential water evaporation visualized by the thermal images. This study extends the fundamental understanding of the evaporation of saline water from porous media.

  6. [Physical activity and electronic media use in children and adolescents: results of the KiGGS study: first follow-up (KiGGS wave 1)].

    Science.gov (United States)

    Manz, K; Schlack, R; Poethko-Müller, C; Mensink, G; Finger, J; Lampert, T

    2014-07-01

    Physical activity during childhood and adolescence has numerous health benefits, while sedentary behavior, especially electronic media use, is associated with the development of overweight. Therefore, the promotion of physical activity during childhood and adolescence is an integral part of national public health efforts. The aim of this article is to describe the physical activity behavior of German children and adolescents based on the nationwide data of the German Health Interview and Examination Survey for Children and Adolescents (KiGGS wave 1). Furthermore, the association between physical activity and sports participation and use of screen-based media in youth aged 11 to 17 years was analyzed. The analyses included data from 10,426 children and adolescents aged 3-17 years collected by telephone interviews. Children older than 11 years answered the questions by themselves, whereas a parent was interviewed for younger children. The descriptive analyses were performed under consideration of social and demographic factors. According to the results of KiGGS wave 1 a total of 77.5% (95% Cl 76.0-78.9 %) of the children and adolescents participated in sports activities, and 59.7% (58.1-61.3 %) were members of a sports club. The recommendation of the World Health Organization (WHO) to be physically active at least 60 min per day was achieved by 27.5% (26.0-28.9 %). Children and adolescents with a low socioeconomic status (SES) participated less in sports activities than children of higher SES groups. Excessive use of screen-based media was more likely to be associated with lack of sports participation than with a lack of physical activity. In the future, preventive measures should promote the daily physical activity of children and adolescents and additionally encourage children and adolescents with low SES to participate in sports activities.

  7. Seasonal differential expression of KiSS-1/GPR54 in the striped hamsters (Cricetulus barabensis) among different tissues.

    Science.gov (United States)

    Xu, Laixiang; Xue, Huiliang; Li, Shenning; Xu, Jinhui; Chen, Lei

    2017-05-01

    Kisspeptins and G protein coupled receptor (GPR54) play significant roles in regulating reproductive activity among seasonally reproductive animals; however, the mechanisms of KiSS-1 and GPR54 gene affecting the seasonal reproduction in striped hamster are still unknown. In this study, real-time quantitative polymerase chain reaction was employed to examine the expression profiles of KiSS-1 and GPR54 in the hypothalamus, ovaries, testes, uterus and epididymis of striped hamsters across 4 different seasons. Our results showed that, across different seasons, the KiSS-1 expression mode of male striped hamsters and the GPR54 expression mode of female striped hamsters were consistent with the seasonal photoperiod in the hypothalamus. Meanwhile, across different seasons, the expression profile of KiSS-1 in the testes and the GPR54 expression profile of male striped hamsters in the hypothalamus were consistent with the intensity of their seasonal reproductive activity. Among different tissues, the expression trend for GPR54 is consistent across 4 seasons, while that for KiSS-1 is tissue-dependent. The expression trend for GPR54 across 4 seasons is the same regardless of gender, while that for KiSS-1 is dramatically different and sex-dependent across different seasons. These results suggest that the expressions of KiSS-1 and GPR54 in the striped hamsters were regulated by complicated mechanisms, and the regulatory mechanisms in the striped hamsters are seasonal-dependent and sex-dependent. This research will provide a theoretical basis for studying how KiSS-1 and GPR54 affect seasonal reproduction and the mechanisms behind their influence. © 2016 International Society of Zoological Sciences, Institute of Zoology/Chinese Academy of Sciences and John Wiley & Sons Australia, Ltd.

  8. An analysis of potassium iodide (KI) prophylaxis for the general public in the event of a nuclear accident

    Energy Technology Data Exchange (ETDEWEB)

    Behling, H.; Behling, K. [S. Cohen & Associates, Inc., McLean, VA (United States); Amarasooriya, H.; Kotsch, J. [Scientech, Inc., Rockville, MD (United States)

    1995-02-01

    A generic difficulty encountered in cost-benefit analyses is the quantification of major elements that define the costs and the benefits in commensurate units. In this study, the costs of making KI available for public use, and the avoidance of thyroidal health effects predicted to be realized from the availability of that KI (i.e., the benefits), are defined in the commensurate units of dollars.

  9. The proliferation marker pKi-67 organizes the nucleolus during the cell cycle depending on Ran and cyclin B.

    Science.gov (United States)

    Schmidt, Mirko H H; Broll, Rainer; Bruch, Hans-Peter; Bögler, Oliver; Duchrow, Michael

    2003-01-01

    The proliferation marker pKi-67 ('Ki-67 antigen') is commonly used in clinical and research pathology to detect proliferating cells, as it is only expressed during cell-cycle progression. Despite the fact that this antigen has been known for nearly two decades, there is still no adequate understanding of its function. This study has therefore identified proteins that interact with pKi-67, using a yeast two-hybrid system. A mammalian two-hybrid system and immunoprecipitation studies were used to verify these interactions. Among other cell-cycle regulatory proteins, two binding partners associated with the small GTPase Ran were identified. In addition, DNA-structural and nucleolus-associated proteins binding to pKi-67 were found. Moreover, it was demonstrated that the N-terminal domain of pKi-67 is capable of self-binding to its own repeat region encoded by exon 13. Since RanBP, a protein involved in the transport of macromolecules over the nuclear lamina, was found to be a binding partner, a possible effect of pKi-67 on the localization of cell-cycle regulatory proteins was proposed. To test this hypothesis, a tetracycline-responsive gene expression system was used to induce the pKi-67 fragments previously used for the two-hybrid screens in HeLa cells. Subsequent immunostaining revealed the translocation of cyclin B1 from cytoplasm to nucleoli in response to this expression. It is suggested that pKi-67 is a Ran-associated protein with a role in the disintegration and reformation of the nucleolus and thereby in entry into and exit from the M-phase. Copyright 2002 John Wiley & Sons, Ltd.

  10. Effect of KiFAY on Performance, Insulin-like Growth Factor-1, and Thyroid Hormones in Broilers

    Directory of Open Access Journals (Sweden)

    Amit Kini

    2016-10-01

    Full Text Available A comparative study was performed to investigate the efficacy of KiFAY as a feed additive on performance parameters, thyroid, and pancreatic hormone levels in broilers. Ninety birds (Vencobb 400 were randomly divided into three groups viz., Control (no DL-methionine supplementation, Treatment1 (containing added DL-methionine and Treatment 2 (containing KiFAY and without DL-methionine supplementation. The performance parameters (weekly body weight, body weight gain, feed intake, and feed consumption ratio were recorded and calculated during the whole study of 4 weeks. Analyses of insulin and insulin-like growth factor (IGF 1, triiodothyronine (T3, thyroxine (T4 and thyroid stimulating hormone (TSH were performed at the end of the study. The results show that birds on supplementation of KiFAY performed significantly (p<0.001 better than other treatments. The weekly body weight, body weight gain, feed in-take and feed consumption ratio improved in KiFAY treated birds. The study found an increase in insulin and IGF1 levels (p<0.001 in KiFAY compared with the other treatments. Serum T3, T4, and TSH levels in the Treatment 2 were higher than other treatments (p<0.001. The KiFAY supplementation was able to improve performance with associated responses at a hormonal level in broilers.

  11. Suprabasal expression of Ki-67 as a marker for the severity of oral epithelial dysplasia and oral squamous cell carcinoma

    Directory of Open Access Journals (Sweden)

    Nidhi Dwivedi

    2013-01-01

    Full Text Available Background: Transition of the normal oral epithelium to dysplasia and to malignancy is featured by increased cell proliferation. To evaluate the hypothesis of distributional disturbances in proliferating and stem cells in oral epithelial dysplasia and oral squamous cell carcinoma (OSCC. Aim: To evaluate layer wise expression of Ki-67 in oral epithelial dysplasia and in OSCC. Materials and Methods: Thirty histologically confirmed cases of oral epithelial dysplasia, fifteen cases of OSCC and five cases of normal buccal mucosa were immunohistochemically examined and nuclear expression of Ki-67 was counted according to basal, parabasal, and suprabasal layers in epithelial dysplasia and number of positive cells per 100 cells in OSCC as labeling index (LI. Results: Suprabasal expression of Ki-67 increased according to the severity of epithelial dysplasia and the difference was statistically significant ( P < 0.001. The mean Ki-67LI was 12.78 for low risk lesions, 28.68 for high risk lesions, 39.45 for OSCC and 13.6 for normal buccal mucosa. Conclusion: The results of the present study demonstrate the use of proliferative marker Ki-67 in assessing the severity of epithelial dysplasia. Suprabasal expression of Ki-67 provides an objective criteria for determining the severity of epithelial dysplasia and histological grading of OSCC.

  12. Evaporative Gasoline Emissions and Asthma Symptoms

    Science.gov (United States)

    Gordian, Mary Ellen; Stewart, Alistair W; Morris, Stephen S

    2010-01-01

    Attached garages are known to be associated with indoor air volatile organic compounds (VOCs). This study looked at indoor exposure to VOCs presumably from evaporative emissions of gasoline. Alaskan gasoline contains 5% benzene making benzene a marker for gasoline exposure. A survey of randomly chosen houses with attached garages was done in Anchorage Alaska to determine the exposure and assess respiratory health. Householders were asked to complete a health survey for each person and a household survey. They monitored indoor air in their primary living space for benzene, toluene, ethylbenzene and xylenes for one week using passive organic vapor monitoring badges. Benzene levels in homes ranged from undetectable to 58 parts per billion. The median benzene level in 509 homes tested was 2.96 ppb. Elevated benzene levels in the home were strongly associated with small engines and gasoline stored in the garage. High concentrations of benzene in gasoline increase indoor air levels of benzene in residences with attached garages exposing people to benzene at levels above ATSDR’s minimal risk level. Residents reported more severe symptoms of asthma in the homes with high gasoline exposure (16%) where benzene levels exceeded the 9 ppb. PMID:20948946

  13. Influence of Oil on Refrigerant Evaporator Performance

    Science.gov (United States)

    Kim, Jong-Soo; Nagata, Karsuya; Katsuta, Masafumi; Tomosugi, Hiroyuki; Kikuchi, Kouichiro; Horichi, Toshiaki

    In vapor compression refrigeration system using oil-lubricated compressors, some amount of oil is always circulated through the system. Oil circulation can have a significant influence on the evaporator performance of automotive air conditioner which is especially required to cool quickly the car interior after a period standing in the sun. An experimental investigation was carried out an electrically heated horizontal tube to measure local heat transfer coefficients for various flow rates and heat fluxes during forced convection boiling of pure refrigerant R12 and refrigerant-oil mixtures (0-11% oil concentration by weight) and the results were compared with oil free performance. Local heat transfer coefficients increased at the region of low vapor quality by the addition of oil. On the other hand, because the oil-rich liquid film was formed on the heat transfer surface, heat transfer coefficients gradually decreased as the vapor quality became higher. Average heat transfer coefficient reached a maximum at about 4% oil concentration and this trend agreed well with the results of Green and Furse. Previous correlations, using the properties of the refrigerant-oil mixture, could not predict satisfactorily the local heat transfer coefficients data. New correlation modified by oil concentration factor was developed for predicting the corresponding heat transfer coefficient for refrigerant-oil mixture convection boiling. The maximum percent deviation between predicted and measured heat transfer coefficient was within ±30%.

  14. Energy consumption during Refractance Window evaporation of selected berry juices

    Energy Technology Data Exchange (ETDEWEB)

    Nindo, C.I.; Tang, J. [Washington State University, Pullman, WA (United States). Dept. of Biological Systems Engineering; Powers, J.R. [Washington State University, Pullman, WA (United States). Dept. of Food Science and Human Nutrition; Bolland, K. [MCD Technologies, Tacoma, WA (United States)

    2004-07-01

    The Refractance Window evaporator represents a novel concept in the design of evaporation systems for small food processing plants. In this system thermal energy from circulating hot water is transmitted through a plastic sheet to evaporate water from a liquid product flowing concurrently on the top surface of the plastic. The objectives of this study were to investigate the heat transfer characteristics of this evaporator, determine its energy consumption, and capacity at different tilt angles and product flow rates. The system performance was evaluated with tap water, raspberry juice, and blueberry juice and puree as feed. With a direct steam injection heating method, the steam economy ranged from 0.64 to 0.84, while the overall heat transfer coefficient (U) was 666 W m{sup -2} {sup o}C{sup -1}. Under this condition, the highest evaporation capacity was 27.1 kg h{sup -1} m{sup -2} for blueberry juice and 31.8 kg h{sup -1} m{sup -2} for blueberry puree. The energy consumption was 2492-2719 kJ kg{sup -1} of water evaporated. Installation of a shell and tube heat exchanger with better temperature control minimized incidences of boiling and frequent discharge of condensate. The steam economy, highest evaporation rate and overall heat transfer coefficient increased to 0.99, 36.0 kg h{sup -1} m{sup -2} and 733 W m{sup -2} {sup o}C{sup -1}, respectively. [Author].

  15. Research on the evaporation of gasoline on beach sand

    Energy Technology Data Exchange (ETDEWEB)

    Berqueiro, J.R.; Dominguez, F.; Pons, J.M

    Gasoline evaporation is an importent factor in spill behavour. When a gasoline spill occurs on beach sand, part of the gasoline is spread over the sand surface while the rest is being absorbed. The spread and absorption rate depend on, amoung other things, the permeability of the sand which in turn also depends on it's water content. It is important to study the effects of gasoline evaporation on sand beaches in order to determine when risk of explosion is low, so that cleaning of the polluted beach surface can be carried out without danger. The effects of the evaporation of 90 and 97 octane (normal and super) gasoline on beach sand have been studied using the tray evaporation technique as described in the literature. The size of the sand particles have been included along with temperature and air speed as variables in the evaporation process. The effects of gasoline on the retention capacity of three distinct types of sand particles, as well as the effects of water in the sand, have been studied for normal and super gasolines. The following conclusions can be drawn: sand retention capacity is inversely proportional to sand particle size; when sand is moistened, its gasoline retention capacity increases proportionally with the decreasing particle size; with the same sand fractions and air speed conditions; the evaporation rate increases with increasing air speeds; with the same sand fractions and air speed conditions the evaporation rate increases with temperature; given the same temperature and air conditions, a gasoline spill on coarse sand evaporates faster than one on medium sand; and given the same temperatures and air speed conditions, the evaporation rate of normal gasoline spreading over any of the three types of sand is always higher than super gasoline due to the higher volatility of the 90 octane gasoline. 10 refs., 1 fig., 3 tabs.

  16. Evaluating the reliability of point estimates of wetland reference evaporation

    Directory of Open Access Journals (Sweden)

    H. Gavin

    2003-01-01

    Full Text Available The Penman-Monteith formulation of evaporation has been criticised for its reliance upon point estimates so that areal estimates of wetland evaporation based upon single weather stations may be misleading. Typically, wetlands comprise a complex mosaic of land cover types from each of which evaporative rates may differ. The need to account for wetland patches when monitoring hydrological fluxes has been noted. This paper presents work carried out over a wet grassland in Southern England. The significance of fetch on actual evaporation was examined using the approach adopted by Gash (1986 based upon surface roughness to estimate the fraction of evaporation sensed from a specified distance upwind of the monitoring station. This theoretical analysis (assuming near-neutral conditions reveals that the fraction of evaporation contributed by the surrounding area increases steadily to a value of 77% at a distance of 224 m and thereafter declines rapidly. Thus, point climate observations may not reflect surface conditions at greater distances. This result was tested through the deployment of four weather stations on the wetland. The resultant data suggested that homogeneous conditions prevailed so that the central weather station provided reliable areal estimates of reference evaporation during the observation period March–April 1999. This may be a result of not accounting for high wind speeds and roughness found in wetlands that lead to widespread atmospheric mixing. It should be noted this analysis was based upon data collected during the period March-April when wind direction was constant (westerly and the land surface was moist. There could be more variation at other times of the year that would lead to greater heterogeneity in actual evaporation. Keywords: evaporation, Penman-Monteith, automatic weather station, fetch, wetland

  17. Maldistribution in airewater heat pump evaporators. Part 1: Effects on evaporator, heat pump and system level

    DEFF Research Database (Denmark)

    Mader, Gunda; Palm, Björn; Elmegaard, Brian

    2015-01-01

    This paper presents an approach to quantify the effect of evaporator maldistribution onoperating costs of air-water heat pumps. In the proposed simulation model maldistributionis induced by two parameters describing refrigerant phase and air flow distribution.Annual operating costs are calculated...... based on heat pump performance at distinct operatingconditions. Results show that percentage increase of operating costs is similar for thethree considered climate zones, even though the effect of maldistribution on heat pumpperformance varies with operating conditions. Differences in terms of absolute...

  18. Do Lipids Retard the Evaporation of the Tear Fluid?

    DEFF Research Database (Denmark)

    Rantamaki, A. H.; Javanainen, M.; Vattulainen, I.

    2012-01-01

    PURPOSE. We examined in vitro the potential evaporation-retarding effect of the tear film lipid layer (TFLL). The artificial TFLL compositions used here were based on the present knowledge of TFLL composition. METHODS. A custom-built system was developed to measure evaporation rates at 35 degrees C....... Lipids were applied to an air-water interface, and the evaporation rate through the lipid layer was defined as water loss from the interface. A thick layer of olive oil and a monolayer of long-chain alcohol were used as controls. The artificial TFLLs were composed of 1 to 4 lipid species: polar...

  19. Modelling of boiler heating surfaces and evaporator circuits

    DEFF Research Database (Denmark)

    Sørensen, K.; Condra, T.; Houbak, Niels

    2002-01-01

    Dynamic models for simulating boiler performance have been developed. Models for the flue gas side and for the evaporator circuit have been developed for the purpose of determining material temperatures and heat transfer from the flue gas side to the water-/steam side in order to simulate...... the circulation in the evaporator circuit. The models have been developed as Differential-Algebraic-Equations (DAE) and MATLAB has been applied for the integration of the models. In general MATLAB has proved to be very stable for the relatively stiff equation systems. Experimental verification is planned...... at a full scale plant equipped with instrumentation to verify heat transfer and circulation in the evaporator circuit....

  20. Impact, absorption and evaporation of raindrops on building facades

    DEFF Research Database (Denmark)

    Abuku, Masaru; Janssen, Hans; Poesen, Jean

    2009-01-01

    . Finally, the experimental and numerical data were used in a more precise three-dimensional simulation of impact, absorption and evaporation of random and discrete wind-driven raindrops. This was compared With the common one-dimensional simulation of absorption and evaporation at the facade considering......In this paper, the impact, absorption and evaporation of raindrops oil building facades is investigated by experimental and numerical means. Laboratory experiments were carried Out to study the impact of water drops with different diameters, impact speeds and impact angles oil a porous building...