Functional identification of a GORK potassium channel from the ancient desert shrub Ammopiptanthus mongolicus (Maxim.) Cheng f.

Science.gov (United States)

Li, Junlin; Zhang, Huanchao; Lei, Han; Jin, Man; Yue, Guangzhen; Su, Yanhua

2016-04-01

A GORK homologue K(+) channel from the ancient desert shrub Ammopiptanthus mongolicus (Maxim.) Cheng f. shows the functional conservation of the GORK channels among plant species. Guard cell K(+) release through the outward potassium channels eventually enables the closure of stomata which consequently prevents plant water loss from severe transpiration. Early patch-clamp studies with the guard cells have revealed many details of such outward potassium currents. However, genes coding for these potassium-release channels have not been sufficiently characterized from species other than the model plant Arabidopsis thaliana. We report here the functional identification of a GORK (for Gated or Guard cell Outward Rectifying K(+) channels) homologue from the ancient desert shrub Ammopiptanthus mongolicus (Maxim.) Cheng f. AmGORK was primary expressed in shoots, where the transcripts were regulated by stress factors simulated by PEG, NaCl or ABA treatments. Patch-clamp measurements on isolated guard cell protoplasts revealed typical depolarization voltage gated outward K(+) currents sensitive to the extracelluar K(+) concentration and pH, resembling the fundamental properties previously described in other species. Two-electrode voltage-clamp analysis in Xenopus lavies oocytes with AmGORK reconstituted highly similar characteristics as assessed in the guard cells, supporting that the function of AmGORK is consistent with a crucial role in mediating stomatal closure in Ammopiptanthus mongolicus. Furthermore, a single amino acid mutation D297N of AmGORK eventually abolishes both the voltage-gating and its outward rectification and converts the channel into a leak-like channel, indicating strong involvement of this residue in the gating and voltage dependence of AmGORK. Our results obtained from this anciently originated plant support a strong functional conservation of the GORK channels among plant species and maybe also along the progress of revolution.

Teatras popieriaus lape: Egono Schiele’s ekspresionistiniai autoportretai | Das Theater auf dem Papierblatt: zu den expressionistischen Selbstbildnissen von Egon Schiele

Directory of Open Access Journals (Sweden)

Dalia Kolytaitė

2004-01-01

Full Text Available Im Werk von Egon Schiele ist der Körper (besonders sein eigener mit seinen mannigfaltigen Ausdrucksformen ein zentrales Thema. Die stark ausgeprägte und sehr spezifische Körpersprache entwickelte der Künstler vor dem Spiegel, wovon nicht nur biographische Daten, sondern auch Photos zeugen. Mit dem ausdrucksvollen Variieren seines Körpers präsentiert Schiele seine Neigung zum Wechseln der Identität, der Rollen, des Selbst, wobei er sich gleichzeitig in drei Positionen befindet: des Darstellers, des Regisseurs und des Zuschauers.Als Objekt der Analyse wurden die sechs Selbstbildnisse ausgewählt: „Selbstbildnis mit kariertem Hemd“ (1917, „Der Prediger (Selbstbildnis“ (1913, „Der Kämpfer (Selbstbildnis“ (1913, „Sitzender männlicher Akt (Selbstbildnis“ (1917, „Der Tänzer (Selbstbildnis“ (1911, „Männlicher Halbakt mit rotem Lendentuch (Selbstbildnis“ (1914. Sie stellen verschiedene plastischen Konfigurationen des Körpers im Raum dar. Obwohl diese Bilder in unterschiedlichen Jahren entstanden sind, lassen sich alle sechs Selbstbildnisse aufgrund der ähnlichen Darstellungsweise, Manier und derselben Technik als ein Pantomimestück betrachten. Für eine solche Betrachtungsweise spricht nicht nur die visuelle Assoziation – der Körper in allen Bildern stellt gleichsam stillgestellte Fragmente einer Bewegung dar, wie man dies bei den Photoherausgaben von Pantomimen oder beim Drehen eines Stummfilmes (sie haben ja die gleichen Elemente Bild und Bewegung beobachten kann. Den Anstoß für eine solche Behauptung gibt die Kunstgattung der Pantomime selbst. Sie ist ja „die große schweigende Kunst“, „das Spiel des bewusst bewegten Körpers“, „die Kunst der Form“, und das „Material, aus dem diese Form geschaffen wird, ist der menschliche Körper“. Schieles Selbstbildnisse entsprechen ihren Grundforderungen: dem begrenzten Raum, der Beleuchtung, dem eng am Körper anliegenden Kostüm, der sehr pers

Pärnu on Eesti funktsionalismi lipulaev / Anu Villmann

Index Scriptorium Estoniae

Villmann, Anu

2006-01-01

Pärnu uusehitistest - Seedri tänava elamud (arhitekt Kalle Vellevoog), kortermaja Tammsaare ja Lehe tänava nurgal (arhitekt Tanel Tuhal arhitektuuribüroost Luhse ja Tuhal) ja kesklinna koolide võimla (arhitektid Katrin Koov, Siiri Vallner, Kaire Nõmm ja Heidi Urb arhitektuuribüroost KAVA KAVA). Pärnu arhitektuurist võtavad sõna Pärnu Linnavalitsuse arhitekt Karri Tiigisoon, Helle-Ann Urgard, Tanel Tuhal, Hardi Lehemaa ja Toomas Unt

Entropy generation analysis of the revised Cheng-Minkowycz problem for natural convective boundary layer flow of nanofluid in a porous medium

Directory of Open Access Journals (Sweden)

Rashidi Mohammad Mehdi

2015-01-01

Full Text Available The similar solution on the equations of the revised Cheng-Minkowycz problem for natural convective boundary layer flow of nanofluid through a porous medium gives (using an analytical method, a system of non-linear partial differential equations which are solved by optimal homotopy analysis method. Effects of various drastic parameters on the fluid and heat transfer characteristics have been analyzed. A very good agreement is observed between the obtained results and the numerical ones. The entropy generation has been derived and a comprehensive parametric analysis on that has been done. Each component of the entropy generation has been analyzed separately and the contribution of each one on the total value of entropy generation has been determined. It is found that the entropy generation as an important aspect of the industrial applications has been affected by various parameters which should be controlled to minimize the entropy generation.

Effect of Da-Cheng-Qi Decoction on Pancreatitis-Associated Intestinal Dysmotility in Patients and in Rat Models

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Jianlei Zhao

2015-01-01

Full Text Available The impairment of intestinal motility and related infectious complications are the predominant clinical phenomenon in patients with severe acute pancreatitis (SAP. We aimed to investigate the effects of Da-Cheng-Qi decoction (DCQD on the gastrointestinal injury in SAP patients and the potential mechanism involved in rats. DCQD was enema administered to 70 patients for 7 days in West China Hospital. Mortality and organ failure during admission were observed and blood samples for laboratory analysis were collected. We also experimentally examined plasma inflammatory cytokines in rat serum and carried the morphometric studies of the gut. Intestinal propulsion index and serum and tissue vasoactive intestinal peptide (VIP were also detected. Though DCQD did not affect the overall incidence of organ failure, it shortened the average time of paralytic intestinal obstruction and decreased the morbidity of infectious complications in patients with SAP. Compared with untreated rats, the DCQD lowered the levels of proinflammatory cytokine and decreased the mean pathological intestinal lesion scores. The VIP level in intestinal tissue or serum in DCQD group was obviously lowered and intestinal propulsion index was significantly improved. In conclusion, DCQD has good effect on pancreatitis-associated intestinal dysmotility in patients and in rat models.

Kas vajame maavalitsust? / Egon Valdaru

Index Scriptorium Estoniae

Valdaru, Egon

2007-01-01

Ilmunud ka: Pärnu Postimees, 10. mai 2007, lk. 19; Oma Saar, 15. mai 2007, lk. 3; Harjumaa, 15. mai 2007, lk. 2; Koit, 15. mai 2007, lk. 6; Virumaa Teataja, 18. mai 2007, lk. 11; Põhjarannik, 22. mai 2007, lk. 2; Severnoje Poberezhje, 22. mai 2007, lk. 2. Autor peab maavalitsuste kaotamist olukorras, kus neil on palju kohustusi, mida keegi teine ei saa ega suuta täita, ilmselgeks rumaluseks

In Vivo Fast Induction of Homogeneous Autopolyploids via Callus in Sour Jujube (Ziziphus acidojujuba Cheng et Liu

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Qinghua Shi

2016-05-01

Full Text Available Polyploidization has been demonstrated as a very effective approach in fruit tree improvement. Sour jujube (Ziziphus acidojujuba Cheng et Liu is a promising diploid wild, traditional fruit species (2n = 2x = 24 that is rich in vitamin C, which is the main rootstock of Chinese jujube (Z. jujuba Mill.. The novel method we developed for rapid in vivo induction of homogeneous autopolyploids (IVIHA via callus in Chinese jujube was first applied and further optimized in sour jujube. Under optimized conditions, an average of one pure autotetraploid shoot could be regenerated from one treated branch, thereby indicating a relatively high efficiency rate. A total of 9 pure autotetraploid genotypes were created, and one of these was released as a new cultivar named ‘Zhuguang’ in 2015. Moreover, unexpected octoploids and hexaploids were also simultaneously created and detected. The leaves of tetraploids were thicker, broader, and darker in color than those of the original diploids, whereas the leaf sizes of octoploids were much smaller compared to that of diploids. However, stoma size increased with the occurrence of ploidy, mainly from diploid to octoploid. The well grown ploidies of jujube included diploids, triploids, and tetraploids. Anatomical observation indicated that adventitious buds/shoots emerged from the callus that formed on the cut, which was then followed by the development of connective vascular tissues between the adventitious bud and the stock plant tissue. This study demonstrates the universality of the IVIHA method that was initially developed in Chinese jujube, as well as provides a foundation for high-efficiency pure polyploid induction in sour jujube.

Riigikohus saatis eksametniku süüdimõistmise teisele ringile

Index Scriptorium Estoniae

2011-01-01

Riigikohus tühistas endise tehnilise järelevalve ameti asejuhi Egon Hirvsoo süüdimõistmise pistisevõtmises ja ASi Jupiter Plus pistiseandmises ning saatis süüasja tagasi uurimiseks Harju maakohtusse

Faking it / Mari Laaniste

Index Scriptorium Estoniae

Laaniste, Mari, 1977-

2001-01-01

Pseudodokumentaalfilm "Not Flammable" : stsenarist, režissöör, monteerija ja produtsent Raimo Jõerand : operaator Madis Mihkelsoo : helilooja Toivo Tulev : diktoritekst Egon Nuter ja John C. Sullivan : Concordia Ülikool, Exitfilm ja Kanal2 2000

[The affinity between Le family of Tong Ren Tang and acu-moxibustion as viewed from Mian xue tang zhen jiu ji cheng (Mian Xuetang's Synthetic Work of Acu-moxibustion)].

Science.gov (United States)

Huang, L X

2017-11-28

This compilation process of Mian xue tang zhen jiu ji cheng ( Mian Xuetang ' s Synthetic Work of Acu - moxibustion )was quite mysterious, the book's advent coincidentally met with several major historical events which made its value of decoding its historical functions far beyond its academic value. The editor of this book is Le Xianyang, the founder of Tong Ren Tang. While compiling this book, he also made a replica of Ming-Dynasty's Zhengtong bronze statue. More than 200 years later, Le Jingyu, the 12th generation of the Le family revised Ming Tang Tu inherited from his ancestors and engraved Ming Tang Tu on the stone for its standardization. This great achievement of Le family was no less than the recasting of the Tiansheng bronze statue and the reengraving Tong ren shu xue zhen jiu tu jing ( Illustrated Manual of Acupuncture Points of the Bronze Figure ) by support of state power for building the Beijing Imperial Hospital in the eighth year of the Zhengtong reign (1443).

Energy in buildings on-line (EGon). Main phase - Final report; Energie im Gebaeude online (EGon). Hauptphase - Schlussbericht

Energy Technology Data Exchange (ETDEWEB)

Stettler, S.; Toggweiler, P.

2009-10-15

A prototype service was developed to measure and evaluate the space heating energy consumption in buildings in an automated, cost-efficient way. The service consists of a low cost hardware and an internet portal which visualises and evaluates the data. In 10 buildings taking part in the building programme of the Climate Cent Foundation a hardware was installed. It measured heating energy consumption and daily sent this data via GPRS to a central server in Berne, Switzerland. Additionally, information about local ambient temperature and solar irradiation was gathered from weather satellites and stored together with the measurement data on the central server. A customised software analysed the data and visualised them. All data, graphs and results were stored in a password protected area, accessible via internet. Measurement data were correlated in a multiple linear regression with the daily average ambient temperature and solar irradiation. The correlation coefficient R2 was higher than 90% for 5 of the buildings (higher than 65% for 9 buildings). Yearly space heating energy consumption in a standard year was estimated by applying the regression parameters to the daily values of ambient temperature and solar irradiation for one year using Meteonorm data. For building owners, architects, space heating planners and energy experts, a similar service as applied in our study could be useful for several purposes: (i) Determine and visualise the real energy consumption and energy performance indicator of a building; (ii) Check if the energy consumption of a certain building meets the expectations / calculations; (iii) Verification of the success of a renovation; (iv) Identify energy leakages / energy saving potential in buildings; (v) Optimise space heating control of buildings; (vi) Gather information for a planned renovation of a building (insulation or renewal of heating installation). The project participants plan to improve the existing prototype and start a second measurement campaign with more buildings in winter 2009/2010. (authors)

Biznes võhodit iz teni / Jevgeni Ashihmin

Index Scriptorium Estoniae

Ashihmin, Jevgeni

2006-01-01

Maksu- ja tolliameti kontrollosakonna juht Egon Veermäe hindab Narva linnavalitsuse püüdeid linnaeelarve tulubaasi tõstmisel. Linnavalitsus saatis ligi neljasajale ettevõttele soovituse tõsta oma töötajate palku ning korrastada maksulaekumine linnaeelarvesse

Informe

Directory of Open Access Journals (Sweden)

Egon Lichetenberger

1950-10-01

Full Text Available Informe del doctor Egon Lichetenberger ante el Consejo Directivo de la Facultad, sobre el  curso de especialización en Anatomía Patológica patrocinado por la Kellogg Foundation (Departamento de Patología

Hvad er forskning? Normer, videnskab og samfund.

DEFF Research Database (Denmark)

forskningsvurdering. Hugo F. Alrøe og Egon Noe: Et perspektivisk blik på videnskabelig uenighed og ekspertise. Cathrine Hasse: Forskerens læreproces - et kritisk, realistisk perspektiv. David Favrholdt: Om viden og videnskab. Jens Hebor: Demarkationsproblemet. Jan Faye: Hvordan adskilles astronomi fra astrologi? Finn...

Journal of Chemical Sciences | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Chemical Sciences. Cheng-Li Yao. Articles written in Journal of Chemical Sciences. Volume 121 Issue 1 January 2009 pp 89-93 Full Papers. Sucrose/bovine serum albumin mediated biomimetic crystallization of calcium carbonate · Cheng-Li Yao Wang-Hua Xu Ai-Min Ding Jin-Mao Zhu.

Ekspressi 10võistlus : grande finale

Index Scriptorium Estoniae

1999-01-01

Eesti Ekspressi 10. sünnipäevale pühendatud fotokonkurss. Eesti Ekspressi T-särgid saavad Uku Visnapuu, Meljo Mutso, Andres Maarits, Raili Laiv, Martin Allik, H. Veide, Kairi Kull, Urmas Liit, Ahto Murumaa, Tiit Mõtus, Endel Puusalu, Egon Kivi, Ivika Kärner

Lens Model

DEFF Research Database (Denmark)

Nash, Ulrik William

2014-01-01

Firms consist of people who make decisions to achieve goals. How do these people develop the expectations which underpin the choices they make? The lens model provides one answer to this question. It was developed by cognitive psychologist Egon Brunswik (1952) to illustrate his theory of probabil...

Soome film Sõpruses

Index Scriptorium Estoniae

2007-01-01

Täna on Sõpruses A. Kaurismäki "Äärelinna tuled", mille ees näeb lühimängufilmi "Vägev võlur" ("The Great Magician") : režissöör Elisabet Gustafsson : osades Egon Nuter, Maria Klenskaja : Eesti - Rootsi - Prantsusmaa 2006

Reconsidering Constructivism in Qualitative Research

Science.gov (United States)

Lee, Cheu-Jey George

2012-01-01

This article examines constructivism, a paradigm in qualitative research that has been propagated by Egon Guba, Yvonna Lincoln, and Norman Denzin. A distinction is made between whether the basic presuppositions of constructivism are credible compared to those of a competing paradigm and whether constructivism's beliefs are internally consistent.…

A Descriptive Analysis of a Problem-Based Learning Police Academy

Science.gov (United States)

Makin, David A.

2016-01-01

In the 1970s, Egon Bitner offered a critique of police academy training, signified by the ability to train compliant soldier-bureaucrats rather than competent practitioners. Over the years, subsequent training models have been implemented, evaluated, and modified in an attempt to exceed what has been deemed adequate training. This research…

Stemcell Information: SKIP000522 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available ... Yes ... Linzhao Cheng Linzhao Cheng Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...Cell Engineering, and Department of Gynecology & Obstetrics, Johns Hopkins Univer...sity School of Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology & Ob...stetrics, Johns Hopkins University School of Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...ne Linzhao Cheng Linzhao Cheng Information Only Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology

Evokace, inspirace, dedikace — zmínky o Honze Krejcarové v díle Egona Bondyho

Directory of Open Access Journals (Sweden)

Martin Machovec

2017-11-01

Full Text Available Egon Bondy’s poetry, fiction, and even philosophical essays contain a lot of factual remarks, both explicit and anonymous (albeit quite transparent, on the woman he met by the end of 1948 and with whom he was in a love-affair for many years. However, Honza Krejcarová seems to have inspired Bondy in a number of other cases. Some fictitious female characters in his literary work are likely to be shaped by the image the poet had created about his ‚femme fatale‘. On the other hand, Krejcarová’s own literary heritage is comparatively modest in its scope. The voluminous ‚letter to Egon Bondy‘ (1962, together with the memoir biography on her mother Milena Jesenská are very important among her works. In the letter, she expressed the gist of her aesthetics and ideas; only in her private correspondence — contrary to her works of fiction published in the sixties — could she write openly, without the interference of any censorship and self-censorship.

Statistical Diversions

Science.gov (United States)

Petocz, Peter; Sowey, Eric

2008-01-01

In this article, the authors focus on hypothesis testing--that peculiarly statistical way of deciding things. Statistical methods for testing hypotheses were developed in the 1920s and 1930s by some of the most famous statisticians, in particular Ronald Fisher, Jerzy Neyman and Egon Pearson, who laid the foundations of almost all modern methods of…

Marketinaren aplikazioa pauso berriak programan:komunikazio plan baten proposamena

OpenAIRE

Idoeta Saez, Lara

2016-01-01

Lan honetan Pauso Berriak programaren eraginkortasuna handitzeko marketinak eskaintzen duen aukera aztertu dut, aplikagarrienak zaizkion marketin alorrak jorratuz,bereziki marketin soziala, eta komunikazio plan baten lerro nagusiak zehaztuz. Xede publiko ezberdin asko egon daitezke programa honetan. Hala nola, adimen urritasuneko pertsonak, familiak, Gureak eta Atzegi, administrazioa, enpresak eta Gipuzkoako gizartea, baina Gipuzkoako enpresetan zentratuko naiz xede h...

Ingliterapeut õpetab inimesi hirmudest lahti laskma / Egon Valdaru

Index Scriptorium Estoniae

Valdaru, Egon

2007-01-01

Kätlin Roovik alias Crystal Ra Lakshmi tuleb 3. oktoobril Viljandisse, et näidata oma dokumentaalfilmi "Kiirtee taevasse" ja korraldada vaimne õhtu. K. Roovik on antropoloog ja aminoloog, kes usub inglitesse ja korraldab ingliõhtuid

Kas julgeme kanda vastutust Eesti ees / Egon Valdaru

Index Scriptorium Estoniae

Valdaru, Egon

2007-01-01

Ilmunud ka: Pärnu Postimees, 15. veebr. 2007, lk. 15; Sakala, 15. veebr. 2007, lk. 2; Võrumaa Teataja, 15. veebr. 2007, lk. 2; Oma Saar, 16. veebr. 2007, lk. 5; Koit, 17. veebr. 2007, lk. 6. Autori sõnul pole sisuline valimiskampaania alanud, erakondade enesetutvustus on peaasjalikult koosnenud teiste mustamisest ja enda ülistamisest

Perspectives on biogeochemistry

National Research Council Canada - National Science Library

Degens, Egon T

1989-01-01

... Heidelberg New York London Paris Tokyo CopyrightProfessor Dr. EGON T. DEGENS formerly Institute of Biogeochemistry and Marine Chemistry at the Center of Marine Research and Climatology University of Hamburg BundesstraBe 55 2000 Hamburg 13, FRG t ISBN 978-3-540-50191-6 DOl 10.1007/978-3-642-48879-5 ISBN 978-3-642-48879-5 (eBook) Library of Con...

Comment on "A spectroscopic comparison of selected Chinese kaolinite, coal bearing kaolinite and halloysite--a mid-infrared and near-infrared study" and "Infrared and infrared emission spectroscopic study of typical Chinese kaolinite and halloysite" by Hongfei Cheng et al. (2010).

Science.gov (United States)

Kloprogge, J Theo

2015-02-05

In two papers Cheng et al. (2010) reported in this journal on the mid-infrared, near-infrared and infrared emission spectroscopy of a halloysite from Hunan Xianrenwan, China. This halloysite contains around 8% of quartz (SiO2) and nearly 9% gibbsite (Al(OH)3). In their interpretation of the spectra these impurities were completely ignored. Careful comparison with a phase pure halloysite from Southern Belgium, synthetic gibbsite, gibbsite from Minas Gerais, and quartz show that these impurities do have a marked influence on the mid-infrared and infrared emission spectra. In the near-infrared, the effect is much less pronounced. Quartz does not show bands in this region and the gibbsite bands will be very weak. Comparison still show that the presence of gibbsite does contribute to the overall spectrum and bands that were ascribed to the halloysite alone do coincide with those of gibbsite. Copyright © 2014 Elsevier B.V. All rights reserved.

Pärnu turismikonverents

Index Scriptorium Estoniae

2006-01-01

2005. aasta 1. detsembril toimus Strand Spa & Konverentsihotellis Pärnu 10. turismikonverents. Ülevaade OÜ Turismimaailm konsultandi Ain Hinsbergi, Pärnu linnavolikogu esimehe Ahti Kõo, Tiit Kase, AS-i Strand juhatuse liikme Egon Elsteini, Kuressaare linnavolikogu liikme Urmas Treieli, Tartu linnapea Laine Jänese, välisministeeriumi infobüroo direktori Krista Kilveti ning TÜ Pärnu Kolledzhi turismimajanduse lektori Heli Müristaja sõnavõttudest

Stemcell Information: SKIP000529 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available Linzhao Cheng Linzhao Cheng Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology ...dicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology & Obstetrics, Johns H...opkins University School of Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...Linzhao Cheng Information Only Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...ng, and Department of Gynecology & Obstetrics, Johns Hopkins University School of

CLEAR: Cross-Layer Exploration for Architecting Resilience

Science.gov (United States)

2017-03-01

unavailable, or in an economy mode (low resilience, low power mode) when ABFT is available. However, the overheads outweigh benefits (details in [Cheng 16b...layer r Design, Automation , & Test in Europe, 2010. [Chen 05] Chen, Z. and J. Dong table real number codes based on random m Lecture Notes in...tolerate soft errors in processor c ACM/EDAC/IEEE Design Automation Conf., 2016. [Cheng 16b] Cheng, E., et al. -layer exploration for architecting

Stemcell Information: SKIP000531 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available ... Linzhao Cheng Linzhao Cheng Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...ing, and Department of Gynecology & Obstetrics, Johns Hopkins University School o...f Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology & Obstetrics, Joh...ns Hopkins University School of Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...eng Linzhao Cheng Information Only Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology

Stemcell Information: SKIP000530 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available ... Linzhao Cheng Linzhao Cheng Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...ing, and Department of Gynecology & Obstetrics, Johns Hopkins University School o...f Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology & Obstetrics, Joh...ns Hopkins University School of Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...eng Linzhao Cheng Information Only Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology

An Improved Biclustering Algorithm and Its Application to Gene Expression Spectrum Analysis

OpenAIRE

Qu, Hua; Wang, Liu-Pu; Liang, Yan-Chun; Wu, Chun-Guo

2016-01-01

Cheng and Church algorithm is an important approach in biclustering algorithms. In this paper, the process of the extended space in the second stage of Cheng and Church algorithm is improved and the selections of two important parameters are discussed. The results of the improved algorithm used in the gene expression spectrum analysis show that, compared with Cheng and Church algorithm, the quality of clustering results is enhanced obviously, the mining expression models are better, and the d...

Stemcell Information: SKIP000524 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available nzhao Cheng Linzhao Cheng Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology & ...Obstetrics, Johns Hopkins University School of Medicine Stem Cell Program, Institute for Cell Engineering, a...cine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology & Obstetrics, Johns Hop...kins University School of Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gyne...nzhao Cheng Information Only Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology

Stemcell Information: SKIP000526 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available nzhao Cheng Linzhao Cheng Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology & ...cine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology & Obstetrics, Johns Hop...kins University School of Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...nzhao Cheng Information Only Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...Obstetrics, Johns Hopkins University School of Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecolo

Stemcell Information: SKIP000528 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available Linzhao Cheng Linzhao Cheng Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology ...dicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology & Obstetrics, Johns H...opkins University School of Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...Linzhao Cheng Available Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology & Ob...stetrics, Johns Hopkins University School of Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology

Stemcell Information: SKIP000527 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available nzhao Cheng Linzhao Cheng Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology & ...cine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology & Obstetrics, Johns Hop...kins University School of Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...nzhao Cheng Available Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology & Obst...etrics, Johns Hopkins University School of Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology

Stemcell Information: SKIP000523 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available nzhao Cheng Linzhao Cheng Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology & ...cine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology & Obstetrics, Johns Hop...kins University School of Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...nzhao Cheng Information Only Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...Obstetrics, Johns Hopkins University School of Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecolo

Stemcell Information: SKIP000525 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available nzhao Cheng Linzhao Cheng Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology & ...cine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology & Obstetrics, Johns Hop...kins University School of Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...nzhao Cheng Information Only Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...Obstetrics, Johns Hopkins University School of Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecolo

Pramana – Journal of Physics | Indian Academy of Sciences

Indian Academy of Sciences (India)

dimensional coupled double-distribution-function lattice Boltzmann models for compressible Navier–Stokes equations. RUO-FAN QIU YAN-CHENG YOU CHENG-XIANG ZHU RONG-QIAN CHEN JIAN-FENG ZHU. Research Article Volume 89 Issue ...

Effect of dietary polyunsaturated fatty acids and Vitamin E on serum oxidative status in horses performing very light exercise

Directory of Open Access Journals (Sweden)

Liviana Prola

2010-01-01

Full Text Available In sporting horses the use of dietary polyunsaturated fatty acids (PUFAs could enhance performance because these fatty acids are very important in membrane permeability, and in particular they seem to increase the possibility of long chain fatty acids entering mythochondria to be burnt. The composition of cellular membranes and lipoprotein fatty acids com- position is strictly related to dietary fat quality; percentages of polyunsaturated fatty acids and amount of antioxidants also affect tissue susceptibility to lipid peroxidation. Six horses were used in a latin square design in which three homogeneous groups were subsequently assigned three dif- ferent dietary treatments for one month each: Control group (C: basic diet; Oil group (O: Basic diet + 200g/day oil rich in PUFAs (Crossential GLA TG20, Croda ®; Vitamin E group (O+E: basic diet + 200 g/day oil rich in PUFAs (Crossential GLA TG20, Croda ® + 5 g/day α-toco- pheryl-acetate (Egon-E, Acme ®. At the end of each experimental period blood samples were taken by jugular vein puncture. Serum oxidative status was evaluated by TBARs and d-ROMs assessment. Oxidative markers showed the high- est mean values for the oil group, even if no statistically significant differences were found.

Introducing 3D U-statistic method for separating anomaly from ...

Indian Academy of Sciences (India)

judging from a geochemical point of view and tries to separate subpopulations and determine anomalous areas. ... based on distribution model, statistical analysis of data and without geochemistry expert judgment. (Sinclair 1991; Cheng et al. 1996; Cheng 1999). The only controller factor of two error types of e1 and.

Una Amistad y una Vocacion: Carlos Sanmartin Barberi

OpenAIRE

Carlos Sanmartin Barberi

1998-01-01

Discurso Pronunciado por el Dr. EGON LICHTENBERGER en su recepción como Miembro Honorario de la Academia Nacional de Medicina.

Con motivo de haber sido distinguido para presentarme en este recinto respetable para recibir la medalla de Miembro Honorario, revisé la lista de los académicos honorarios y demás miembros de la Academia Nacional de Medicina. Que la persona, que les dirige la palabra, pase a engrosar la lista de figuras tan emine...

Journal of Chemical Sciences | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Chemical Sciences. Hai-Liang Zhu. Articles written in Journal of Chemical Sciences. Volume 121 Issue 4 July 2009 pp 463-470. Synthesis, antimicrobial activity of lamotrigine and its ammonium derivatives · Yong Qian Peng-Cheng Lv Lei Shi Rui-Qin Fang Zhong-Cheng Song Hai-Liang Zhu.

Targeting the I-Kappa-B Kinase Epsilon (IKKe) for Breast Cancer Therapy

Science.gov (United States)

2009-09-01

Mol Pharm 2009, 6(3):772-779. 15. Cheng K, Fraga D, Zhang C, Kotb M, Gaber AO, Guntaka RV, Mahato RI: Adenovirus-based vascular endothelial growth...Pharmaceutics 2009, 6, 772– 779. (27) Cheng, K.; Fraga, D.; Zhang, C.; Kotb, M.; Gaber , A. O.; Guntaka, R. V.; Mahato, R. I. Adenovirus-based vascular

Česká próza v periodě 1945-1948

OpenAIRE

HÜBELBAUEROVÁ, Kristýna

2013-01-01

The thesis focuses on the reception of existentialism in the Czech entourage in 1945-1948. The theoretical part of the chapter is dedicated to Václav Černý and his understanding of existensialism. We are going to be focusing on the professional and theoretical texts from Jaroslav Červinka, Jindřich Chalupecký, Václav Navrátil, Jan Patočka and Ladislav Rieger, which are processing the theme. In the practical part we are going to analyze the pieces from Dušan Pala, Miroslav Hanuš and Egon Hosto...

An Era of Change

Institute of Scientific and Technical Information of China (English)

无

2006-01-01

Supported by new technologies,new media forms are changing the way people get access to informationWatching IPTV on her computer, shopping online and maintaining a column on sina.com, one of China's largest Internet portals, Cheng Chan, 24, a freelance magazine columnist,represents the community of people who are using new technologies to access information and lead their lives. Cheng has only her name, telephone

Punding following posterior cerebral artery infarction: a case report and review of literature

Directory of Open Access Journals (Sweden)

Lin CI

2017-03-01

Full Text Available Cho-I Lin,1 Yu-Ching Lin,1–3 Wei-Chih Lien,1 Pei-Chun Hsieh,1 Sheng-Han Lin,1 Ta-Shen Kuan1,2 1Department of Physical Medicine and Rehabilitation, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan; 2Department of Physical Medicine and Rehabilitation, College of Medicine, National Cheng Kung University, Tainan, Taiwan; 3Medical Device Innovation Center, National Cheng Kung University, Tainan, Taiwan Introduction: Punding is a complex stereotyped behavior, characterized by excessiveness, non-goal orientation, and repetitiveness. It is mostly associated with Parkinson’s disease, and very few cases in non-Parkinson’s disease have been reported. We report a case of punding associated with supratentorial ischemic stroke.Case presentation: We present a 70-year-old man with left posterior cerebral artery infarction with quetiapine-induced punding manifesting as repetitive unidirectional body turning. Remission of punding behavior ensued after cessation of quetiapine and administration of clonazepam.Conclusion: This case describes the clinical course of quetiapine-induced punding in a patient with left posterior cerebral artery infarction. It suggests clonazepam may serve as a treatment option for poststroke punding. Keywords: punding, stereotyped behavior, stroke, quetiapine, clonazepam

Discurso del Académico Efraím Otero Ruiz, Presidente de la Sociedad Colombiana de Historia de la Medicina En la Recepción como Miembro Honorario del Dr. Egón Lichtenberger.

OpenAIRE

Efraim Otero Ruiz

1998-01-01

Bogotá, Mayo 15 de 1997

Señores Académicos, señoras, señores :

Retornamos antes de ocho días a esta alta tribuna del pensamiento académico, esta vez para acoger y exaltar como Académico Honorario al Profesor Dr. Egon Lichtenberger. En él consagramos no solamente a la Anatomía Patológica como especialidad, ausente muchos lustros de este recinto bogotano, desde la época de su numerario y posterior Presidente Dr. Juan Pablo Llinás, sino especialmente ...

Antioxidant Capacity and Proanthocyanidin Composition of the Bark of Metasequoia glyptostroboides

OpenAIRE

Chen, Fengyang; Zhang, Lin; Zong, Shuling; Xu, Shifang; Li, Xiaoyu; Ye, Yiping

2014-01-01

Metasequoia glyptostroboides Hu et Cheng is the only living species in the genus Metasequoia Miki ex Hu et Cheng (Taxodiaceae), which is well known as a “living fossil” species. In the Chinese folk medicine, the leaves and bark of M. glyptostroboides are used as antimicrobic, analgesic, and anti-inflammatory drug for dermatic diseases. This study is the first to report the free radical scavenging capacity, antioxidant activity, and proanthocyanidin composition of the bark of M. glyptostroboid...

Retos de la comunicación educativa en el siglo XXI

OpenAIRE

VV.AA,

2012-01-01

Lourdes LATAPÍ RUIZ, El aislamiento originado por las TICS. Irene FERNÁNDEZ MONFERRER ; Pedro ARENAS WILSON, Escuela, medios y aprendizaje : perspectiva crítica para la aplicación de habilidades educomunicativas en el aula. Almudena ESTEBAN ; Andrés ROSENBERG, La importancia de despertar inquietudes. Myriam CATRILEO ; María Alejandra HERNÁNDEZ, Escuela virtual, una alternativa para el cambio de saberes. Lorena CAIMANQUE ; Luis RIVERA, Enseñanza : una de las más altas poesías. Cheng Cheng TANG...

[The relationship between acupuncture-moxibustion theory of DOU Hanqing and Neo- Confucianism].

Science.gov (United States)

Li, Baojin; Huang, Longxiang

2018-02-12

For the construction factors of acupuncture-moxibustion theory of DOU Hanqing , a doctor in Jin-Yuan Dynasty, we studied his life, acupuncture-moxibustion theory and culture background in the History of Medicine and Philosophy of Science & Technology. It was found that the major source of DOU Hanqing ' s Confucianism was the CHENG - ZHU Neo-Confucianism. The data show that Neo-Confucianism played an important role in the enrichment of his human nature, spirit, moral cultivation and political talent, making him a scholar in the Jin - Yuan dynasty, also shaping his medical ethics, medical skill and acupuncture-moxibustion theory. The inheritance, development and application of CHENG - ZHU Neo-Confucianism provided the most fundamental thinking, research methods and patterns for DOU Hanqing to interpret the acupuncture classics, summarize his teachers' experience and develop his theoretical system. DOU Hanqing ' s acupuncture-moxibustion practice and theory reached a new level, because he took acupuncture-moxibustion as one of the knowledge investigation and attainment of CHENG - ZHU Neo-Confucianism.

Documentation to the workshop 'Cluster in the environmental protection economy'; Dokumentation zum Workshop ''Cluster in der Umweltschutzwirtschaft''

Energy Technology Data Exchange (ETDEWEB)

NONE

2009-12-11

Within the workshop 'Cluster in the environmental protection economy' at the Umweltbundesamt (Dessau-Rosslau, Federal Republic of Germany) at 27th November, 2008, the following lectures were held: (a) Which contribution can cluster and cluster politics contribute to the promotion of the environmental protection economy? (Harald Legler); (b) Cluster in the environmental protection economy: Targets and expectations (Dieter Rehfeld); (c) Demands at the management of clusters (Karin Hoerhan); (d) Demands at the cluster politics in the environmental protection economy (Bernhard Hausberg); (e) Photovoltaics in Eastern Germany (Johann Wackenbauer); (f) Automotive industry in Bergisches Land (Thomas Lemken); (g) Competence centre environment Augsburg-Schwaben (Egon Beckord).

Heat transfer in MHD unsteady stagnation point flow with variable wall temperature

Digital Repository Service at National Institute of Oceanography (India)

Soundalgekar, V.M.; Murty, T.V.R.; Takhar, H.S.

stream_size 8739 stream_content_type text/plain stream_name Indian_J_Pure_Appl_Math_21_384.pdf.txt stream_source_info Indian_J_Pure_Appl_Math_21_384.pdf.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8.... Soc. A224 (1954), 1-23. 2. S. I. Cheng and D. Elliott, Heat Transfer and Fluid Mech. IlIstitUfl?, S:anfoni University. Stanford (CA). 1956, p.p.221-38. 3. S. I. Cheng, Quart. appl. Math. 14 (1956-1957), 337-52. (\\ K. T. Yang, J. Appl. Mecll. (Tr. ASME...

Oxidative Lung Injury in Virus-Induced Wheezing

Science.gov (United States)

2015-07-01

respiratory syncytial virus Yashoda M. Hosakote,1 Narayana Komaravelli,1 Nicolas Mautemps,1 Tianshuang Liu,1 Roberto P. Garofalo,1,2,3 and Antonella Casola1,2,3...1097/MNH.0b013e3283430651. 5. Li L, Whiteman M, Guan YY, Neo KL, Cheng Y, Lee SW, Zhao Y, Baskar R, Tan CH, Moore PK. 2008. Characterization of a novel...L, Whiteman M, Guan YY, Neo KL, Cheng Y, Lee SW, Zhao Y, Baskar R, Tan CH, Moore PK. Characterization of a novel, water-soluble hydrogen sulfide

Determination of blood concentrations of main active compounds in Zi-Cao-Cheng-Qi decoction and their total plasma protein binding rates based on hollow fiber liquid phase microextraction coupled with high performance liquid chromatography.

Science.gov (United States)

Li, Miaomiao; Chen, Xuan; Hu, Shuang; Wang, Runqin; Peng, Xiaoli; Bai, Xiaohong

2018-01-01

Oil-in-salt hollow fiber liquid phase microextraction coupled with high performance liquid chromatography ultraviolet detection (HPLC-UV) was developed for determination of the blood concentrations of the main active compounds, hesperidin, honokiol, shikonin, magnolol, emodin and β,β'-dimethylacrylshikonin, after oral administration of Zi-Cao-Cheng-Qi decoction (ZCCQD) and their total plasma protein binding rates. In the procedure, a hollow fiber segment was immersed in organic solvent to fill the solvent in the fiber lumen and wall pore, and then the fiber was immersed into sodium chloride solution to cover a thin salt membrane on the fiber wall pore filling organic solvent. Various factors affecting the procedure, such as extraction solvent, sample phase pH, stirring rate, extraction time, NaCl concentration and fiber immersion time in the NaCl solution, were optimized. Under the optimum conditions, good linearities (r 2 ≥0.9905), low limits of detection (0.7-2.5ng/mL) or quantitation (1.2-12ng/mL), satisfactory precision (2.6%-12.8%) and accuracy (81.0%-114.2%) of this method, were observed. The results showed that, after oral administration of a 25g/kg dose, (1) the blood concentrations (at 0.5h) of hesperidin, honokiol, shikonin, magnolol, emodin and β,β'-dimethylacrylshikonin were 0.45, 0.40, 0.48, 0.74, 0.11 and 1.11μg/mL, respectively; (2) the total plasma protein binding rates of the six active compounds were 42.0% (hesperidin), 71.8% (honokiol), 64.6% (shikonin), 77.7% (magnolol), 75.3% (emodin) and 75.7% (β,β'-dimethylacrylshikonin), respectively. The proposed procedure coupled with HPLC shows obvious advantages, such as low solvent consumption, simple operation, high sensitivity and strong purifying and can be used for the determination of both the blood concentrations and total plasma protein binding rates of active compounds in traditional Chinese medicine. Copyright © 2017 Elsevier B.V. All rights reserved.

78 FR 14556 - Cheng Yi Liang: Debarment Order

Science.gov (United States)

2013-03-06

.... 1001 and securities fraud, a Federal felony offense under 15 U.S.C. 78j(b) and 78ff. FDA's finding that debarment is appropriate is based on the felony conviction for securities fraud referenced herein for... execution of trades on national securities exchanges, resulting in total profits and losses avoided of $3...

Rehabilitation for a child with recalcitrant anti-N-methyl-D-aspartate receptor encephalitis: case report and literature review

Directory of Open Access Journals (Sweden)

Guo YH

2014-11-01

Full Text Available Yao-Hong Guo,1 Ta-Shen Kuan,1,2 Pei-Chun Hsieh,1 Wei-Chih Lien,1 Chun-Kai Chang,1 Yu-Ching Lin1–3 1Department of Physical Medicine and Rehabilitation, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan; 2Department of Physical Medicine and Rehabilitation, College of Medicine, National Cheng Kung University, Tainan, Taiwan; 3Medical Device Innovation Center, National Cheng Kung University, Tainan, Taiwan Abstract: Anti-N-methyl-d-aspartate (anti-NMDA receptor encephalitis is a newly recognized, potentially fatal, but treatable autoimmune disease. Good outcome predictors include milder severity of symptoms, no need for intensive care unit admission, early aggressive immunotherapy, and prompt tumor removal. We report a case of a young girl aged 3 years 2 months and diagnosed as recalcitrant anti-NMDA receptor encephalitis without any underlying neoplasm. The patient had initial symptoms of behavioral changes that progressed to generalized choreoathetosis and orofacial dyskinesia, which resulted in 6 months of hospitalization in the pediatric intensive care unit. One year after initial onset of the disease, she had only achieved the developmental age of an infant aged 6–8 months in terms of gross and fine motor skills, but she resumed total independence in activities of daily living after receiving extensive immunotherapy and 28 months of rehabilitation. Our brief review will help clinical practitioners become more familiar with this disease and the unique rehabilitation programs. Keywords: anti-NMDA receptor encephalitis, autoimmune encephalitis, rehabilitation, cognition deficits

The effects of magnetite (Fe3O4 nanoparticles on electroporation-induced inward currents in pituitary tumor (GH3 cells and in RAW 264.7 macrophages

Directory of Open Access Journals (Sweden)

Liu YC

2012-03-01

Full Text Available Yen-Chin Liu1, Ping-Ching Wu2, Dar-Bin Shieh2–5, Sheng-Nan Wu3,6,71Department of Anesthesiology, 2Institute of Oral Medicine and Department of Stomatology, 3Department of Physiology, National Cheng Kung University Hospital, College of Medicine, 4Advanced Optoelectronic Technology Center, 5Center for Micro/Nano Science and Technology, National Cheng Kung University, 6Innovation Center for Advanced Medical Device Technology, National Cheng Kung University, 7Department of Anatomy and Cell Biology, National Cheng Kung University Medical College, Tainan, TaiwanAims: Fe3O4 nanoparticles (NPs have been known to provide a distinct image contrast effect for magnetic resonance imaging owing to their super paramagnetic properties on local magnetic fields. However, the possible effects of these NPs on membrane ion currents that concurrently induce local magnetic field perturbation remain unclear.Methods: We evaluated whether amine surface-modified Fe3O4 NPs have any effect on ion currents in pituitary tumor (GH3 cells via voltage clamp methods.Results: The addition of Fe3O4 NPs decreases the amplitude of membrane electroporation-induced currents (IMEP with a half-maximal inhibitory concentration at 45 µg/mL. Fe3O4 NPs at a concentration of 3 mg/mL produced a biphasic response in the amplitude of IMEP, ie, an initial decrease followed by a sustained increase. A similar effect was also noted in RAW 264.7 macrophages.Conclusion: The modulation of magnetic electroporation-induced currents by Fe3O4 NPs constitutes an important approach for cell tracking under various imaging modalities or facilitated drug delivery.Keywords: iron oxide, ion current, free radical

.

Directory of Open Access Journals (Sweden)

Eduardo Thomas Dublé

2005-01-01

Full Text Available Inside the dramatic world of Egon Wolf, social playacting establishes itself as a major theme. Its multiple and diverse modes of representation in his extensive dramaturgy could be summarized in two, appearing with different mances and combination throughout his work. On the one hand, they become the fundament of the ritual conventions of the commonplace acts of the characters, with the function of dissembling and self protection in front of the social reality which is perceived as hostile. In this case, playacting is a resource intended to neutralize and manipulate the other for personal benefit through masking strategies; but also the ludic element appears with creative and libertarian characteristics that are the character's own, as an option for authenticity.

Evaluation of Intensive Construction Land Use in the Emerging City Based on PSR-Entropy model

Science.gov (United States)

Jia, Yuanyuan; Lei, Guangyu

2018-01-01

A comprehensive understanding of emerging city land utilization and the evaluation of intensive land use in the Emerging City will provide the comprehensive and reliable technical basis for the planning and management. It is an important node. According to the Han cheng from 2008 to 2016 years of land use, based on PSR-Entropy model of land use evaluation system, using entropy method to determine the index weight, the introduction of comprehensive index method to evaluate the degree of land use. The results show that the intensive land use comprehensive evaluation index of Han cheng increased from 2008 to 2015, but the land intensive use can not achieve the standards. The potential of further enhancing space is relatively large.

Effects of carbon ion irradiation on survival rate, catalase and peroxidase activity of alfalfa M1 under low temperature stress

International Nuclear Information System (INIS)

Wang Shuyang; Li Jinghua; Jiang Boling

2014-01-01

In this study, three kinds of alfalfa including Zhonglan 1, BC-04-477 and Ta Cheng were treated with different doses of "1"2C"6"+ (75 keV) heavy ion radiation, and then the influence of survival rate, catalase (CAT) and peroxidase (POD) activity of M1 with low temperature stress were tested. The results showed that under the condition of 400 Gy radiation dose, the survival rate and CAT activity of Zhonglan 1 under low temperature stress have increased by 33.3%, 56.3% respectively compared with those of the control group, while there was no difference in POD activity between those two groups. The survival rate, CAT and POD activity of BC-04-477 treated with low temperature have been improved by 33.3%, 69.2%, 5.1% respectively compared with those of the control group when the radiation dose was 400 Gy. Compared with those of the control group, the survival rate, CAT and POD activity of Ta Cheng under low temperature stress have been improved by 25%, 26%,22.8% respectively when the radiation dose was 800 Gy. These results indicate that the viability and the cold resistance ability of Zhong Lan 1, BC-04-477 and Ta Cheng can be improved by "1"2C"6"+ radiation. (authors)

Taiwan university joins search for antimatter

CERN Multimedia

Chiu, Y

2002-01-01

National Cheng Kung University announced yesterday that it will be joining the Alpha Magnetic Spectrometer, an international scientific research project aimed at looking for antimatter in space (1 page).

Establishment of an eco-compensation fund based on eco-services consumption.

Science.gov (United States)

Liu, Moucheng; Yang, Lun; Min, Qingwen

2018-04-01

Eco-compensation is a type of institutional arrangement that uses economic measures to adjust the relationships among stakeholders in order to conserve and/or sustainably use ecosystem services. The externality of the value of ecosystem services is one of the theoretical bases for eco-compensation. Different types of ecosystem services are consumed by people from different regions. Some are consumed by people living where the services originate, while some are carried by rivers, wind, vehicles or other natural or manmade means to other areas. Thus, the flow and consumption of ecosystem services should be seen as the basis for establishing eco-compensation funds. This paper uses satellite images of the Zhang-Cheng area near Beijing in 2013 to discuss how to establish an eco-compensation fund for stakeholders in this area. Firstly, six important types of ecosystem services in the Zhang-Cheng area were identified based on ecological function zoning, and the value of these ecosystem services was calculated based on ecological pricing methods. Secondly, the field intensity model from physics was used to analyze where Zhang-Cheng area ecosystem services flowed and calculate how much of these services were used by other areas. Thirdly, based on this analysis and calculation, the paper proposes the rates that different stakeholders should invest in the eco-compensation fund, based on their consumption of eco-services. Copyright © 2018 Elsevier Ltd. All rights reserved.

Therapeutic Effects of Water Extract of Arisaema Erubescens Tubers ...

African Journals Online (AJOL)

Purpose: To investigate the anti-arthritic activity of the water extract of Rhizoma Arisaematis (WERA) using collagen II .... Plethysmometer PV-200 (ChengDu Technology. & Market Co. ..... Chung WY. Red ginseng saponin extract attenuates.

Finite element model to study calcium distribution in oocytes ...

African Journals Online (AJOL)

Parvaiz Ahmad Naik

2015-03-20

Mar 20, 2015 ... Department of Mathematics, Maulana Azad National Institute of Technology, Bhopal 462051 ... finite element method has been employed to obtain the solution. ..... Nelson MT, Cheng H, Rubart M. Relaxation of arterial smooth.

Isolation and identification of two galangin metabolites from rat urine ...

African Journals Online (AJOL)

Isolation and identification of two galangin metabolites from rat urine and determination of their in vitro hypolipidemic activity. Xuguang Zhang, Shouqian Cheng, Hailong Li, Xiaopo Zhang, Feng Chen, Youbin Li, Junqing Zhang, Yinfeng Tan ...

Reference: 197 [Arabidopsis Phenome Database[Archive

Lifescience Database Archive (English)

Full Text Available bidopsis thaliana CAX2 cation transporter. 6 959-71 15821993 2004 Dec Plant molecular biology Cheng Ning-Hui|Hirschi Kendal D|Marshall Joy L|Morris Jay L|Pittman Jon K|Shigaki Toshiro

Reaction texture and Fe-Mg zoning in granulite garnet from ...

Indian Academy of Sciences (India)

Author Affiliations. J Ganguly1 B J Hensen2 W Cheng1. Department of Geosciences, University of Arizona, Tucson, AZ 85721, USA. Department of Applied Geology, University of New South Wales, Kensington, NSW 2033, Australia.

75 FR 63857 - In the Matter of: Certain Digital Televisions and Components Thereof; Notice of Investigation

Science.gov (United States)

2010-10-18

..., CA 92618. AmTRAN Technology Co., Ltd., 17f, 268, Lien Cheng Rd., Chungho City, Taipei, 23553, Taiwan... right to appear and contest the allegations of the complaint and this notice, and to authorize the...

Effect of impervious surface area and vegetation changes on mean ...

African Journals Online (AJOL)

adeniyi adeyemi

Land surface temperature (LST) is measured by the surface energy balance, .... climatic and environmental conditions (Cheng et al., 2006). ..... urban areas have generally resulted in a high reflection and emission of solar radiation and greater.

Depression among Congestive Heart Failure Patients: Results of a Survey from Central China

Directory of Open Access Journals (Sweden)

JPMS

2011-10-01

Full Text Available Tabish Hussain, Li Yu Shu, Xiang Cheng, Tumenjavkhlan Sosorburam, A.Seid Adji, Sara Tajammul, Aamra Sartaj (Union Hospital, Tongji Medical College, Huazhong University of Sciences and Technology, Wuhan, China (pages 38-42

Enterovirus 71 Brainstem Encephalitis and Cognitive and Motor Deficits

Directory of Open Access Journals (Sweden)

J Gordon Millichap

2006-12-01

Full Text Available Follow-up studies were conducted in 63 previously healthy children with enterovirus 71 brainstem encephalitis (49 stage II, 7 stage Ilia, and 7 stage Illb at National Cheng Kung University Hospital, Tainan, Taiwan.

Adsorption of Metals from FAME of Nigerian Spent Vegetable Oils ...

African Journals Online (AJOL)

PROF HORSFALL

2018-05-02

May 2, 2018 ... ... are cooking oils that have undergone several cooking process, presented ..... Recovery and conversion of palm olein-derived used frying oil to methyl ... using waste cooking oil from restaurants, In: Cheng. P (ed) Energy ...

Formation and evolution of yardangs activated by Late Pleistocene ...

Indian Academy of Sciences (India)

2School of Tourism, Hebei University of Economics and Business, Shijiazhuang 050061, China. ∗ ... Based on fieldwork, this study ascertained three levels of river terrace in the ...... Cheng J 2009 Practice book of Quaternary geology and geo-.

Molecular cloning and characterization of a novel human kinase ...

Indian Academy of Sciences (India)

Unknown

LINGCHEN GUO, CHAONENG JI, SHAOHUA GU, KANG YING, HAIPENG CHENG,. XIAOGHUA NI ... minal LIM domain proteins that cantain a PDZ domain at the amino terminal ..... Taira M., Evrard J. L., Steinmetz A. and Dawid I. B. 1995.

77 FR 44310 - Quarterly Publication of Individuals, Who Have Chosen To Expatriate, as Required by Section 6039G

Science.gov (United States)

2012-07-27

... JACINTA YEUNG CHEONG CHANG MICHAEL YIO-HOW CHENG NICOLAS VINCENT CHI TELLY TAI HSUAN CHINOY SAMIR MUSTAPHA... TONJA YVONNE SU JIN CHIN SU XIAOBO SARA SHAO SUEN SAMSON C. L. SY KEVIN NEIL TAN LAI HING THARALDSEN...

Placental markers of human exposure to polychlorinated biphenyls and polychlorinated dibenzofurans

International Nuclear Information System (INIS)

Lucier, G.W.; Nelson, K.G.; Everson, R.B.; Wong, T.K.; Philpot, R.M.; Tiernan, T.; Taylor, M.; Sunahara, G.I.

1987-01-01

These studies have evaluated biochemical changes in placentae from humans exposed to rice oil contaminated with polychlorinated biphenyls (PCBs) and polychlorinated dibenzofurans (PCDFs) in Taiwan. Placentae were obtained from nonsmoking women 4 to 5 years after the exposure had occurred. The exposed individuals ingested approximately 1 to 3 g PCBs and 5 mg PCDFs, and many exhibited symptoms characteristic of PCB poisoning. This disease was termed Yu-Cheng in Chinese. Based on data from experimental animals models, the authors examined a number of parameters in placentae from control and exposed women, including arylhydrocarbon hydroxylase (AHH) activity, cytochrome P-450 isozymes, epidermal growth factor (EGF) receptor binding properties and actions, and Ah receptor. They also quantified concentrations of various PCB and PCDF congeners known to be present in the contaminated rice oil. The results revealed a dramatic elevation in placental AHH activity in samples from PCB/PCDF-exposed women. This increase in enzyme activity was associated with a parallel increase in placental microsomal protein immunochemically related to cytochrome P-450 form 6. EGF receptor-mediated autophosphorylation capacity was significantly diminished in PCB/PCDF placentae, but this effect was not associated with changes in plasma membrane EGF receptor binding properties. Two PCDF congeners were detected in Yu-Cheng placentae but not controls. Several PCBs were also detected in much higher concentrations in Yu-Cheng placentae. Surprisingly, placental concentrations of PCBs correlated better with effects than did the PCDFs. The findings are discussed in relation to the risk assessment process

High-Precision Determination of the Pion-Nucleon σ Term from Roy-Steiner Equations

Science.gov (United States)

Hoferichter, Martin; Ruiz de Elvira, Jacobo; Kubis, Bastian; Meißner, Ulf-G.

2015-08-01

We present a determination of the pion-nucleon (π N ) σ term σπ N based on the Cheng-Dashen low-energy theorem (LET), taking advantage of the recent high-precision data from pionic atoms to pin down the π N scattering lengths as well as of constraints from analyticity, unitarity, and crossing symmetry in the form of Roy-Steiner equations to perform the extrapolation to the Cheng-Dashen point in a reliable manner. With isospin-violating corrections included both in the scattering lengths and the LET, we obtain σπ N=(59.1 ±1.9 ±3.0 ) MeV =(59.1 ±3.5 ) MeV , where the first error refers to uncertainties in the π N amplitude and the second to the LET. Consequences for the scalar nucleon couplings relevant for the direct detection of dark matter are discussed.

Borehole Water Pollution and its Implication on Health on the Rural ...

African Journals Online (AJOL)

. ... on human health of such toxicity may require many years of exposure before .... further observed that fluoride accumulation in important regions of the brain, ... Cheng Y X, IQ of children in area of high fluorine content, Chinese Journal of ...

Journal of Earth System Science | Indian Academy of Sciences

Indian Academy of Sciences (India)

Author Affiliations. Li Wei1 2 Cheng Pengfei2 Bei Jinzhong2 Wen Hanjiang2 Wang Hua1 2. School of Geodesy and Geomatics, Wuhan University, Wuhan 430 079, China. Chinese Academic of Surveying and Mapping, Beijing 100 830, China.

Modeling and analysis of large-eddy simulations of particle-laden turbulent boundary layer flows

KAUST Repository

Rahman, Mustafa M.; Samtaney, Ravi

2017-01-01

layer employs stretched spiral vortex subgrid-scale model and a virtual wall model similar to the work of Cheng, Pullin & Samtaney (J. Fluid Mech., 2015). This LES model is virtually parameter free and involves no active filtering of the computed

Journal of Genetics | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Genetics; Volume 96; Online resources. Population genetic diversity of marble goby (Oxyeleotris marmoratus)inferred from mitochondrial DNA and microsatellite analysis. CHENG ZHAO XIAOPING ZHU YICHUN GU QINTAO WANG ZECHENG LI SHAOWU YIN. ONLINE RESOURCES Volume 96 ...

Segmentation of singularity maps in the context of soil porosity

Science.gov (United States)

Martin-Sotoca, Juan J.; Saa-Requejo, Antonio; Grau, Juan; Tarquis, Ana M.

2016-04-01

Geochemical exploration have found with increasingly interests and benefits of using fractal (power-law) models to characterize geochemical distribution, including concentration-area (C-A) model (Cheng et al., 1994; Cheng, 2012) and concentration-volume (C-V) model (Afzal et al., 2011) just to name a few examples. These methods are based on the singularity maps of a measure that at each point define areas with self-similar properties that are shown in power-law relationships in Concentration-Area plots (C-A method). The C-A method together with the singularity map ("Singularity-CA" method) define thresholds that can be applied to segment the map. Recently, the "Singularity-CA" method has been applied to binarize 2D grayscale Computed Tomography (CT) soil images (Martin-Sotoca et al, 2015). Unlike image segmentation based on global thresholding methods, the "Singularity-CA" method allows to quantify the local scaling property of the grayscale value map in the space domain and determinate the intensity of local singularities. It can be used as a high-pass-filter technique to enhance high frequency patterns usually regarded as anomalies when applied to maps. In this work we will put special attention on how to select the singularity thresholds in the C-A plot to segment the image. We will compare two methods: 1) cross point of linear regressions and 2) Wavelets Transform Modulus Maxima (WTMM) singularity function detection. REFERENCES Cheng, Q., Agterberg, F. P. and Ballantyne, S. B. (1994). The separation of geochemical anomalies from background by fractal methods. Journal of Geochemical Exploration, 51, 109-130. Cheng, Q. (2012). Singularity theory and methods for mapping geochemical anomalies caused by buried sources and for predicting undiscovered mineral deposits in covered areas. Journal of Geochemical Exploration, 122, 55-70. Afzal, P., Fadakar Alghalandis, Y., Khakzad, A., Moarefvand, P. and Rashidnejad Omran, N. (2011) Delineation of mineralization zones in

“顺万物之性，游变化之途”——从郭注、成疏《逍遥游》看庄子的思想%＂Complying with the Nature of the Universe and Wandering with the Way of Variety＂： a View of Chong Tzus Ideology from the Explanation of Peripateticism by Guoxiang and Cheng Xuan- ying

Institute of Scientific and Technical Information of China (English)

马荣

2012-01-01

Chong Tzu introduced the term ＂peripatetlclsm＇＂ （.tree wanaenng） m uie wt,liu the ultimate concern of humanity in the real world. Meanwhile, Chong Tzus Peripateticism gave humang life a un- constrained hope in layer upon layer constraints. Therefore, this paper explores the realm and the meaning of Chong Tzu~ ideology from the explanation of Peripateticism by Guoxiang and Cheng Xuan -ying in order to have a better understanding of Chong Tzus ideology from ＂complying with the nature of the universe and wandering with the way of variety＂.%以如何在现实的人间世之中达到对人性的终极关怀，庄子将“逍遥”引入了人间世。同时，庄子的《逍遥游》也是一种给予重重束缚下人生以一种自由的希望，因此，本文即从郭注成玄英疏探讨庄子《逍遥游》的境界及意义，从“顺万物之性，游变化之途”阐述对庄子的思想世界更深入的理解。

Metal oxide blended ZSM-5 nanocomposites as ethanol sensors

Indian Academy of Sciences (India)

Framework of ZSM-5 structure consists of intersecting ... ges quality monitoring, environmental monitoring, indoor air quality and .... metric stretching vibrations of Si–O group [22]. ..... [17] Cheng Y, Liao R H, Li J S, Sun X Y and Wang L J 2008.

Optimization of embryogenic-callus induction and embryogenesis of ...

African Journals Online (AJOL)

Optimization of embryogenic-callus induction and embryogenesis of Glycyrrhiza glabra. Fu Chunhua, Cheng Lei, Lu Gan, Maoteng Li, Ying Yang, Longjiang Yu. Abstract. Glabridin is a major biologically active flavonoid isolated specifically from the root of Glycyrrhiza glabra, which has many pharmacological activities.

inhibits channel and hemichannel functions inducing cataract

Indian Academy of Sciences (India)

2015-06-10

Jun 10, 2015 ... Da), such as metabolites, ions and second messengers between two contacting cells. ... ous gift from Dr David Wan-Cheng Li of Medicine Col- ..... 445,. 201–230. El-Fouly M. H., Trosko J. E. and Chang C.-C. 1987 Scrape-.

African Journal of Biotechnology - Vol 9, No 42 (2010)

African Journals Online (AJOL)

Ragi tapai and Saccharomyces cerevisiae as potential coculture in viscous fermentation medium for ethanol production · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Azlin Suhaida Azmi, Gek Cheng Ngoh, Maizirwan Mel, Masitah Hasan, 7122-7127 ...

77 FR 12235 - Wooden Bedroom Furniture From the People's Republic of China: Initiation of Administrative Review

Science.gov (United States)

2012-02-29

.... Kent Hospitality, Inc. Champion Sun Industries Limited Changshu HTC Import & Export Co., Ltd.* Cheng... Industry Co. Ltd.* Shanghai Hospitality Product Mfg., Co., Ltd. Shanghai Industries Group Shanghai Jian Pu... Co., Ltd.;* Artwork Metal & Plastic Co., Ltd.;* Jibson Industries Ltd.;* Always Loyal International...

Linking ecotoxigenomic tools with ecological data to support river restoration

CSIR Research Space (South Africa)

Jappie, S

2012-10-01

Full Text Available tissues. ACKNOWLEDGMENTS The authors would like to express their sincere gratitude to the Olifants River Forum and the Technology and Human Resources for Industry Programme (THRIP) for the provision of funding, and to Dr Paul Cheng and Liesl Hill...

Editorial: Serving the Optics and Photonics Community for 40 Years.

Science.gov (United States)

Zhang, Xi-Cheng

2017-06-01

Editor-in-Chief Xi-Cheng Zhang celebrates Optics Letters' 40th anniversary by discussing the Journal's success and clarifying an editorial policy that balances the Journal's high standards with the fulfillment of its mission to support the greater optics and photonics community.

Molecular characterization and expression analysis of a hepcidin ...

African Journals Online (AJOL)

Jane

2011-08-03

Aug 3, 2011 ... the liver, intestine and brain were 2.4, 1.5 and 2-fold increase, respectively, compared with the control animals after 5 days .... (sex change) of RFE attracted more attention (Cheng et al., 2003 ...... Molecular Biology. New York: ...

Comparison of long-term clinical outcome between patients with chronic versus acute type B aortic dissection treated by implantation of a stent graft: a single-center report

Directory of Open Access Journals (Sweden)

Chen SL

2013-04-01

Full Text Available Shao-Liang Chen, Jian-Cheng Zhu, Xiao-Bo Li, Fei Ye, Jun-Jie Zhang, Zhi-Zhong Liu, Nai-Liang Tian, Song Lin, Cheng-Yu Lv Nanjing First Hospital, Nanjing Medical University, Nanjing, People's Republic of China Background: Stent grafting for treatment of type B aortic dissection has been extensively used. However, the difference in the long-term clinical outcome between patients with chronic versus acute type B aortic dissection remains unknown. This study aimed to analyze the difference in long-term clinical outcome after endovascular repair for patients with chronic (93% complete false-lumen thrombosis. Untreated tear and type I endoleak were predictors of clinical events during follow-up. Conclusion: Comparable long-term clinical results were achieved in patients with chronic or acute type B aortic dissection after implantation of a stent graft. Keywords: aortic dissection, endovascular repair, procedure-related events, propensity score matching

Operator formulation of the droplet model

International Nuclear Information System (INIS)

Lee, B.W.

1987-01-01

We study in detail the implications of the operator formulation of the droplet model. The picture of high-energy scattering that emerges from this model attributed the interaction between two colliding particles at high energies to an instantaneous, multiple exchange between two extended charge distributions. Thus the study of charge correlation functions becomes the most important problem in the droplet model. We find that in order for the elastic cross section to have a finite limit at infinite energy, the charge must be a conserved one. In quantum electrodynamics the charge in question is the electric charge. In hadronic physics, we conjecture, it is the baryonic charge. Various arguments for and implications of this hypothesis are presented. We study formal properties of the charge correlation functions that follow from microcausality, T, C, P invariances, and charge conservation. Perturbation expansion of the correlation functions is studied, and their cluster properties are deduced. A cluster expansion of the high-energy T matrix is developed, and the exponentiation of the interaction potential in this scheme is noted. The operator droplet model is put to the test of reproducing the high-energy limit of elastic scattering quantum electrodynamics found by Cheng and Wu in perturbation theory. We find that the droplet model reproduces exactly the results of Cheng and Wu as to the impact factor. In fact, the ''impact picture'' of Cheng and Wu is completely equivalent to the droplet model in the operator version. An appraisal is made of the possible limitation of the model. (author). 13 refs

Biclustering of gene expression data using reactive greedy randomized adaptive search procedure.

Science.gov (United States)

Dharan, Smitha; Nair, Achuthsankar S

2009-01-30

Biclustering algorithms belong to a distinct class of clustering algorithms that perform simultaneous clustering of both rows and columns of the gene expression matrix and can be a very useful analysis tool when some genes have multiple functions and experimental conditions are diverse. Cheng and Church have introduced a measure called mean squared residue score to evaluate the quality of a bicluster and has become one of the most popular measures to search for biclusters. In this paper, we review basic concepts of the metaheuristics Greedy Randomized Adaptive Search Procedure (GRASP)-construction and local search phases and propose a new method which is a variant of GRASP called Reactive Greedy Randomized Adaptive Search Procedure (Reactive GRASP) to detect significant biclusters from large microarray datasets. The method has two major steps. First, high quality bicluster seeds are generated by means of k-means clustering. In the second step, these seeds are grown using the Reactive GRASP, in which the basic parameter that defines the restrictiveness of the candidate list is self-adjusted, depending on the quality of the solutions found previously. We performed statistical and biological validations of the biclusters obtained and evaluated the method against the results of basic GRASP and as well as with the classic work of Cheng and Church. The experimental results indicate that the Reactive GRASP approach outperforms the basic GRASP algorithm and Cheng and Church approach. The Reactive GRASP approach for the detection of significant biclusters is robust and does not require calibration efforts.

Tonic and Phasic Dopamine Fluctuations as Reflected in Beta-power Predict Interval Timing Behavior

NARCIS (Netherlands)

Kononowicz, Tadeusz; van Rijn, Hedderik

It has been repeatedly shown that dopamine impacts interval timing in humans and animals (for a review, see Coull, Cheng, & Meck, 2012). Particularly, administration of dopamine agonists or antagonists speeds-up or slows down internal passage of time, respectively (Meck, 1996). This co-variations in

Characterizing slope morphology using multifractal technique: a study from the western continental margin of India.

Digital Repository Service at National Institute of Oceanography (India)

Chakraborty, B.; Karisiddaiah, S.M.; Menezes, A.A.A.; Haris, K.; Gokul, G.S.; Fernandes, W.A.; Kavitha, G.

margin of India. Geo-Mar Lett 26: 114–119. doi: 10.1007/s00367-006-0022-6 Cheng Q, Agterberg FP (1996) Comparison between two types of multifractal modeling. Math Geol 28 (8): 1001–1015 Dandapath S, Chakraborty B, Maslov N, Karisiddaiah SM...

Identification of overexpressed cytokines as serum biomarkers of ...

African Journals Online (AJOL)

Yomi

Taiwan. 4Division of Gastroenterology, Cheng Hsin General Hospital, Taipei, Taiwan. 5Institute of Nuclear Energy Research, Atomic Energy Council, Taoyuan, Taiwan. 6Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan. 7Division of Hepatology, Buddhist Tzu Chi General ...

Journal of Genetics | Indian Academy of Sciences

Indian Academy of Sciences (India)

Yu-Song Guo Zhong-Duo Wang Cheng-Zhong Yan Yu-Lan Zhang Jin-Nan Zheng Yuan-Min Xu Tao Du Chu-Wu Liu · More Details Fulltext PDF ... Aifu Yang Dapeng Sun Shikai Liu Ying Dong Zhong Chen Zunchun Zhou · More Details Fulltext ...

The Economics of Sorruption and Cronyism: an institutional approach

NARCIS (Netherlands)

B. Krug (Barbara); H. Hendrischke (Hans)

2001-01-01

textabstractMoral outrage was the response of the Chinese press, when Cheng Kejie, one of the country's highest officials, Vice-Chairman of the Standing Committee of the National People's Congress (NPC) and former Governor of the Guangxi Zhuang Autonomous Region, was arrested on grounds of

The fostering role of information technology on SMEs' strategic ...

African Journals Online (AJOL)

2013-05-03

May 3, 2013 ... 8Key words: strategic purchasing, information technology (IT), ... 2011); the impact of IT on logistics performance (Kengpol 2007; Lai, Wong & Cheng .... control over performance is possible by considering global solutions in .... the logistics activities between the external suppliers and internal organisational.

Cloning, chromosome localization and features of a novel human ...

Indian Academy of Sciences (India)

Unknown

Math2 may have the same functions in the nervous system. [Guo L., Jiang M., Ma Y., Cheng ... from a human foetal brain cDNA library, and its localiza- tion in the human ... using the BLASTN,. BLASTP and BLASTX algorithms on the NCBI web.

Parental Bonds, Attachment Anxiety, Media Susceptibility, and Body Dissatisfaction: A Mediation Model

Science.gov (United States)

Patton, Sarah C.; Beaujean, A. Alexander; Benedict, Helen E.

2014-01-01

The developmental trajectory of body image dissatisfaction is unclear. Researchers have investigated sociocultural and developmental risk factors; however, the literature needs an integrative etiological model. In 2009, Cheng and Mallinckrodt proposed a dual mediation model, positing that poor-quality parental bonds, via the mechanisms of…

Journal of Chemical Sciences | Indian Academy of Sciences

Indian Academy of Sciences (India)

... YU1 JUAN QIN2 JIAQI ZHANG1 FULIN CHENG1 WENLIANG WU1. College of Chemical Engineering, Nanjing Tech University, Nanjing 210009, People's Republic of China; Technology and Finance Service Center of Jiangsu Province, Productivity Center of Jiangsu Province, Nanjing 210042, People's Republic of China ...

Journal of Chemical Sciences | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Chemical Sciences. Wenzhong Cheng. Articles written in Journal of Chemical Sciences. Volume 126 Issue 6 November 2014 pp 1623-1627 Rapid Communications. Synthesis and properties of a dual responsive hydrogel by inverse microemulsion polymerization · Tao Wan Min Xu Liyi Chen ...

Critical Race Design: An Emerging Methodological Approach to Anti-Racist Design and Implementation Research

Science.gov (United States)

Khalil, Deena; Kier, Meredith

2017-01-01

This article is about introducing Critical Race Design (CRD), a research methodology that centers race and equity at the nucleus of educational opportunities by design. First, the authors define design-based implementation research (DBIR; Penuel, Fishman, Cheng, & Sabelli, 2011) as an equity-oriented education research methodology where…

DETECTION OF K-RAS AND P53 MUTATIONS IN SPUTUM SAMPLES OF LUNG CANCER PATIENTS USING LASER CAPTURE MICRODISSECTION MICROSCOPE AND MUTATION ANALYSIS

Science.gov (United States)

Detection of K-ras and p53 Mutations in Sputum Samples of Lung Cancer Patients Using Laser Capture Microdissection Microscope and Mutation AnalysisPhouthone Keohavong a,*, Wei-Min Gao a, Kui-Cheng Zheng a, Hussam Mady b, Qing Lan c, Mona Melhem b, and Judy Mumford d.<...

[Professor YANG Zhao-min's contribution to the education of modern acupuncture and moxibustion].

Science.gov (United States)

Dong, Qin; Mu, Yan-Yun; Xia, You-Bing; Zhang, Jian-Bin

2012-05-01

It was completely collected and summarized the teaching history and the relevant historical materials of Professor YANG Zhao-min via consulting the literatures, investigation, interview, etc. in this paper. The summaries indicated that from the beginning of running a school, Professor YANG Zhao-min adhered to the CHENG's moral, worked hard and successfully explored and practiced the training pattern of teaching tour for the personnel training of acupuncture and moxibustion. He established the specialty of acupuncture and moxibustion, formatted courses and inherited the feature of practice teaching. He was in charge of the compilation of textbook and engaged in scientific innovation. He inherited the past and forged ahead into the future and had made the decision to cultivate the personnel of acupuncture and moxibustion. Professor YANG Zhao-min had practiced and developed the modern educational thought from the CHENG Dan-an and had made the important contribution to the training of acupuncture and moxibustion professionals.

Role of the Neddylation Enzyme Uba3, A New Estrogen Receptor Corepressor in Breast Cancer

Science.gov (United States)

2006-09-01

vs. MCF7) Gene symbol Genbank MCF7-T MCF-F Description Notch signaling pathway PSEN1 NM_007319 1.33 7.06 Presenilin 1 ( Alzheimer disease 3...Medicine Bloomington, Indiana 47405 3Department of Life Science and Institute of Molecular Biology National Chung Cheng University Chia -Yi Taiwan

Lamb shifts and hyperfine structure in 6Li+ and 7Li+: Theory and experiment

DEFF Research Database (Denmark)

Riis, E.; Sinclair, A. G.; Poulsen, Ove

1994-01-01

. The accuracy of 11 parts per million is the best two-electron Lamb shift measurement in the literature, and is comparable to the accuracies achieved in hydrogen. Theoretical contributions to the two-electron Lamb shift are discussed, including terms of order (alpha Z)(4) recently obtained by Chen, Cheng...

Tropical Cyclone Report

Science.gov (United States)

1989-01-01

CHULALONGKORN UNIVERSITY, BANGKOK LOS ANGELES PUBLIC LIBRARY CHUNG CHENG INSTITUTE, TAIWAN MASS INST OF TECH CITIES SERVICES OIL GAS CORP MCAS FUTENMA CIUDAD ...reached the mountainous oceanic sensible and latent heat sources . The terrain of Laos. system was downgraded to a typhoon at 190600Z, and then to a

Cultural Values and Communication Online: Chinese and Southeast Asian Students in a Taiwan International MBA Class

Science.gov (United States)

Warden, Clyde A.; Chen, Judy F.; Caskey, D'Arcy

2005-01-01

Whereas many researchers have examined differences in values and behavior between Westerners and Asians, fewer have investigated differences within Asian cultural groups. A recent government initiative in Taiwan to encourage international education has led to the development of an international MBA program at the National Cheng Kung University in…

The Role of Language in National and Multinational Enterprises in Taiwan.

Science.gov (United States)

Du-Babcock, Bertha; Babcock, Richard D.

Communication patterns and language use in four national and multinational companies operating in Taiwan illustrate the potential for communication problems when more than one language is in use. The companies include Texas Instruments, Kaohsiung Monomer Company, Ltd., Bank of America, and Cheng-Yia International Corporation. In the four…

Puzzles in B physics

Indian Academy of Sciences (India)

Home; Journals; Pramana – Journal of Physics; Volume 67; Issue 5. Puzzles in physics. Hsiang-Nan Li ... Author Affiliations. Hsiang-Nan Li1 2. Institute of Physics, Academia Sinica, Taipei, Taiwan 115, Republic of China; Department of Physics, National Cheng-Kung University, Tainan, Taiwan 701, Republic of China ...

Safe Gene Therapy for Type 1 Diabetes

Science.gov (United States)

2012-10-01

tiation (Cheng et al, 2007; Gillard et al, 2007). Nevertheless, our data show that the negative selection checkpoint is facilitated by insulin produced...1A diabetes: 2005. Immunol Rev 204: 232–249 Gillard GO, Dooley J, Erickson M, Peltonen L, Farr AG (2007) Aire- dependent alterations in medullary

Characterization and phylogenetic analysis of α-gliadin gene ...

Indian Academy of Sciences (India)

Supplementary data: Characterization and phylogenetic analysis of α-gliadin gene sequences reveals significant genomic divergence in Triticeae species. Guang-Rong Li, Tao Lang, En-Nian Yang, Cheng Liu ... The MITE insertion at the 3 UTR is boxed. Figure 2. The secondary structure of MITE insertion in HM452949.

Evaluation on the resistance to aphids of wheat germplasm ...

African Journals Online (AJOL)

Jane

2011-10-17

Oct 17, 2011 ... Agricultural Sciences, Beijing, 100193, Peoples Republic of China. ... 3College of Plant Protection, Shandong Agricultural University, Taian, ... varieties in Henan Province, China (Li et al., 1998). ... (m a.s.l.), represents the warm temperate continental monsoon ..... Ma R, Chen JL, Cheng DF, Sun JR (2010).

War, trade and piracy in the China Seas (1622-1683)

NARCIS (Netherlands)

Cheng, Weichung

2012-01-01

The objective of this research is to examine the rise and fall of a prominent 17th century Chinese maritime power: the Cheng lineage. It elucidates how, due to the consequences of specific historical circumstances at a crucial moment in time, the Ming imperial administration initially tolerated a

In vitro spore germination and gametophytic growth development of ...

African Journals Online (AJOL)

SAM

2014-06-04

Jun 4, 2014 ... gametophytes were observed namely, filamentous, spatulate and heart stages in the MS culture medium with hormones. After 15 days, the .... However, gametophytic generation is essential in the fern life cycle and very ..... Deng YN, Cheng X, Jiao Y, Chen GJ (2009). The Gametophyte. Development and ...

Numerical study of a Vlasov equation for systems with interacting particles

Energy Technology Data Exchange (ETDEWEB)

Herrera, Dianela; Curilef, Sergio [Departamento de Física, Universidad Católica del Norte, Avenida Angamos 0610, Antofagasta (Chile)

2015-03-10

We solve numerically the Vlasov equation for the self-gravitating sheet model. We used the method introduced by Cheng and Knorr [Comput Phys 22, 330-351 (1976)]. We discuss the quasi-stationary state for some thermodynamical observables, specifically the kinetic energy, whose trend is depicted for early evolution.

Determination of Chemical Constituents of the Marine Pulmonate ...

African Journals Online (AJOL)

Determination of Chemical Constituents of the Marine Pulmonate Slug, Paraoncidium reevesii. B Sun, H Shen, H Wu, L Yao, Z Cheng, Y Diao. Abstract. Purpose: To isolate and identify the chemical components of Paraoncidium reevesii. Methods: Silica gel column chromatography was used to isolate the components from ...

Determining adaptive and adverse oxidative stress responses in human bronical epithelial cells exposed to zinc

Science.gov (United States)

Determining adaptive and adverse oxidative stress responses in human bronchial epithelial cells exposed to zincJenna M. Currier1,2, Wan-Yun Cheng1, Rory Conolly1, Brian N. Chorley1Zinc is a ubiquitous contaminant of ambient air that presents an oxidant challenge to the human lung...

Journal of Astrophysics and Astronomy | Indian Academy of Sciences

Indian Academy of Sciences (India)

2016-01-27

Jan 27, 2016 ... Home; Journals; Journal of Astrophysics and Astronomy; Volume 35; Issue 3. Correlations between Optical Variability and Physical Parameters of Quasars. Wenwen Zuo Xue-Bing Wu Yi-Qing Liu Cheng-Liang Jiao. Part V: Black Holes (or Binary Black Holes) in Blazars Volume 35 Issue 3 September 2014 ...

Pramana – Journal of Physics | Indian Academy of Sciences

Indian Academy of Sciences (India)

Article ID 33 Research Article. Dynamic analysis, circuit implementation and passive control of a novel four-dimensional chaotic system with multiscroll attractor and multiple coexisting attractors · BANG-CHENG LAI JIAN-JUN HE · More Details Abstract Fulltext PDF. In this paper, we construct a novel 4D autonomous chaotic ...

Early encounters between China and Africa: myth or moment ...

African Journals Online (AJOL)

China did indeed have a highly advanced ship building capacity long before the dawn of the West's global age of sail, and archaeological evidence bears testimony to the sophistication of Chinese maritime technology. The article also focuses on the voyages of the legendary Grand Eunuch , Admiral Cheng Ho, undertaken ...

Genomewide identification, classification and analysis of NAC type ...

Indian Academy of Sciences (India)

Supplementary data: Genomewide identification, classification and analysis of NAC type gene family in maize. Xiaojian Peng, Yang Zhao, Xiaoming Li, Min Wu, Wenbo Chai, Lei Sheng, Yu Wang, Qing Dong,. Haiyang Jiang and Beijiu Cheng. J. Genet. 94, 377–390. Table 1. Detailed information of NAC proteins in maize.

Journal of Chemical Sciences | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Chemical Sciences. Mei Luo. Articles written in Journal of Chemical Sciences. Volume 127 Issue 1 January 2015 pp 163-166 Regular Articles. Efficient one-pot synthesis of 2-oxazolines from benzoylacetonitrile and -aminoalcohols mediated by ZnCl2 · Mei Luo Jing Cheng Zhang Hao Yin.

Computer Literacy Education

Science.gov (United States)

1989-01-01

Cognitive Aspect ," AEDS Journal, 18, 3 (Spring 1985) 150. "°Geoffrey Akst, "Computer Literacy: An Interview with Dr. Michael Hoban." Journal of Develop- m...1984. Cheng, Tina T.; Plake, Barbara; and Stevens, Dorothy Jo. "A Validation Study of the Computer Literacy Examination: Cognitive Aspect ." AEDS

Potentiation and Overshadowing of Shape by Wall Color in a Kite-Shaped Maze Using Rats in a Foraging Task

Science.gov (United States)

Cole, Mark R.; Gibson, Laura; Pollack, Adam; Yates, Lynsey

2011-01-01

The interaction between redundant geometric and featural cues in open field search tasks has been examined widely with results that are not always consistent. Cheng (1986) found evidence that when searching for food in rectangular environments, rats used the geometrical characteristics of the environment rather than local featural cues, suggesting…

Saturation mapping of QTL region determining resistance specificity ...

African Journals Online (AJOL)

STORAGESEVER

2009-09-01

Sep 1, 2009 ... S, Ni L, Zhu F, Chen W, Lan L, Lai Y, Cheng Z, Gu M, Jiang J, Li J,. Hong G, Xue Y, Han B ... Katagiri F, Markus Lange B, Moughamer T, Xia Y, Budworth P,. Zhong J, Miguel T, ... Gen. Genet. 261: 58-63. Marrs KA (1996).

Current Trends in Aerospace Engineering Education on Taiwan.

Science.gov (United States)

Hsieh, Sheng-Jii

A proposal for current trends in Aerospace Engineering Education on Taiwan has been drawn from the suggestions made after a national conference of "Workshop on Aerospace Engineering Education Reform." This workshop was held in January 18-20, 1998, at the Institute of Aeronautics and Astronautics, National Cheng Kung University, Tainan,…

Genetic diversity based on SSR markers in maize (Zea mays L.)

Indian Academy of Sciences (India)

Home; Journals; Journal of Genetics; Volume 87; Issue 3. Genetic diversity based on SSR markers in maize (Zea mays L.) landraces from Wuling mountain region in China. Yao Qi-Lun Fang Ping Kang Ke-Cheng Pan Guang-Tang. Research Note Volume 87 Issue 3 December 2008 pp 287-291 ...

Insecticidal activity of essential oil of Cinnamomum cassia and its ...

African Journals Online (AJOL)

XC Liu, J Cheng, NN Zhao, ZL Liu ... Methods: Steam distillation of C. cassis twigs was carried out using a Clavenger apparatus in order to obtain the volatile oils. ... Conclusion: The findings suggest that the essential oil of C. cassis and its constituent compound, trans-cinnamaldehyde, possess potentials for development ...

Journal of Genetics | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Genetics; Volume 95; Issue 1. Distribution and linkage disequilibrium analysis of polymorphisms of GH1 gene in different populations of pigs associated with body size. Yunyun Cheng Songcai Liu Dan Su Chao Lu Xin Zhang Qingyan Wu Siming Li Haoyu Fu Hao Yu Linlin Hao. Research Article ...

Bile acids cycle disruption in patients with nasopharyngeal ...

African Journals Online (AJOL)

2014-12-31

Dec 31, 2014 ... promotes the elevation of interleukin-10 secretion. Cheng-Shi Wang1 ... Nasopharyngeal carcinoma (NPC) is uncommon in the ... Immune function has close relationship with the patho- genesis of ... Liver is the major organ responsible for the synthesis of primary bile acids, and the function of bacteria in the ...

Frequency upconversion in catechin assisted : - square nanoplates

Indian Academy of Sciences (India)

VAIRAPPERUMAL TAMILMANI

2017-11-25

Nov 25, 2017 ... out to be a prominent ligand for its coordination on the surface of the ..... C 113. 14702. 12. Jin J, Gu Y J, Man C W Y, Cheng J, Xu Z, Zhang Y, Wang .... Ding B, Han C, Zheng L, Zhang J, Wang R and Tang. Z 2015 Tuning ...

An algorithm to find all palindromic sequences in proteins

Indian Academy of Sciences (India)

2013-01-20

Jan 20, 2013 ... 1976; Karrer and Gall 1976; Vogt and Braun 1976) and (iii) in the formation of hairpin loops in the newly transcribed RNA. Palindromic sequences are observed in various classes of proteins like histones (Cheng et al. 1989), prion proteins (Sulkowski 1992; Kazim 1993),. DNA-binding proteins (Suzuki 1992; ...

Generating and measuring nondiffracting vector Bessel beams

CSIR Research Space (South Africa)

Dudley, Angela L

2013-09-01

Full Text Available (2006). 12. W. Han, W. Cheng, and Q. Zhan, Opt. Lett. 36, 1605 (2011). 13. F. Cardano, E. Karimi, S. Slussarenko, L. Marrucci, C. de Lisio, and E. Santamato, Appl. Opt. 51, C1 (2012). 14. C. Maurer, A. Jesacher, S. Fürhapter, S. Bernet, and M. Ritsch-Marte...

Development of a New Class of Drugs to Inhibit All Forms of Androgen Receptor in Castration Resistant Prostate Cancers

Science.gov (United States)

2016-10-01

titration methods (protein in the syringe, ligand in the cell), we were able to obtain a reproducible thermogram for the ligand binding reaction...to VPC-14449 as a model drug to assist on other related projects. 1. Tam, K., Dalal, K., Hsing, M., Cheng, C.W., Chiang, Y.T., Sharma, A., Peacock

Total Arterial Off‑pump Coronary Revascularization with a Bilateral ...

African Journals Online (AJOL)

Total Arterial Off‑pump Coronary Revascularization with a Bilateral Internal Mammary Artery Y Graft (208 cases). Jun-Feng Yang, Hong-Chao Zhang1, Cheng-Xiong Gu, Hua Wei. INTRODUCTION. AY graft is a graft formed by the left internal mammary artery (LIMA) connected to the left anterior descending (LAD) artery and ...

Journal of Genetics | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Genetics. Lingchen Guo. Articles written in Journal of Genetics. Volume 81 Issue 1 April 2002 pp 13-17 Perspectives. Cloning, chromosome localization and features of a novel human gene, MATH2 · Lingchen Guo Min Jiang Yushu Ma Haipeng Cheng Xiaohua Ni Yangsheng Jin Yi Xie Yumin ...

Association study of a brain-derived neurotrophic factor polymorphism and short-term antidepressant response in major depressive disorders

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Lung-Cheng Huang

2008-10-01

Full Text Available Eugene Lin1,7, Po See Chen2,6,7, Lung-Cheng Huang3,4, Sen-Yen Hsu51Vita Genomics, Inc., Wugu Shiang, Taipei, Taiwan; 2Department of Psychiatry, Hospital and College of Medicine, National Cheng Kung University, Tainan, Taiwan; 3Department of Psychiatry, National Taiwan University Hospital Yun-Lin Branch, Taiwan; 4Graduate Institute of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; 5Department of Psychiatry, Chi Mei Medical Center, Liouying, Tainan, Taiwan; 6Department of Psychiatry, National Cheng Kung University Hospital, Dou-liou Branch, Yunlin, Taiwan; 7These authors contributed equally to this workAbstract: Major depressive disorder (MDD is one of the most common mental disorders worldwide. Single nucleotide polymorphisms (SNPs can be used in clinical association studies to determine the contribution of genes to drug efficacy. A common SNP in the brain-derived neurotrophic factor (BDNF gene, a methionine (Met substitution for valine (Val at codon 66 (Val66Met, is a candidate SNP for influencing antidepressant treatment outcome. In this study, our goal was to determine the relationship between the Val66Met polymorphism in the BDNF gene and the rapid antidepressant response to venlafaxine in a Taiwanese population with MDD. Overall, the BDNF Val66Met polymorphism was found not to be associated with short-term venlafaxine treatment outcome. However, the BDNF Val66Met polymorphism showed a trend to be associated with rapid venlafaxine treatment response in female patients. Future research with independent replication in large sample sizes is needed to confirm the role of the BDNF Val66Met polymorphism identified in this study.Keywords: antidepressant response, brain-derived neurotrophic factor, major depressive disorder, serotonin and norepinephrine reuptake inhibitor, single nucleotide polymorphisms

In, out, or half way? The European attitude in the speeches of British leaders

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Denise Milizia

2014-07-01

Full Text Available Abstract – It cannot be denied that Britain is normally seen as an awkward partner in EU affairs (George 1994, and in many ways the British have always been half-in: in the two-speed Europe slogan, Britain is seen as a slow traveller (Musolff 2004, as a member that makes slow progress, it if is at all on the European path. The purpose of this paper is to try and unveil, with evidence at hand, the sentiment of the British leaders with respect to the European Union. Interestingly, the current government includes both Conservatives and Lib-Dems leaders, and it is well known that the former have been, more often than not, against Europe whereas the latter are highly passionate about their pro-Europeanism. Interviews, statements and speeches proper are thus analysed and compared: first wordlists are generated, then keywords lists and finally key-clusters lists (Scott 2012, with the purpose of identifying "aboutgrams" (Warren 2010; Sinclair, Tognini Bonelli 2011, and see what the two governments have in common, but mostly what differentiates them with regard to the European Union, i.e. what is prioritized in one administration and was not in another, clearly signalling a change in priorities (Cheng 2004; Cheng et al. 2006; Cheng et al. 2009. The study is a diachronic analysis, in the attempt to see how previous discourses have been reinterpreted, given that forty years after joining the Union the British are still reluctant Europeans who still consider Europe "abroad", thus slowing the "ever-closer union" envisaged in the Treaty of Rome, and who still have been calling for referendums, even more so after the ratification of the Lisbon Treaty.Keywords: European Union, UK, political speeches, opt out, aboutgrams.

In Search of Critical Pedagogy in Sexuality Education: Visions, Imaginations, and Paradoxes

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Sanjakdar, Fida; Allen, Louisa; Rasmussen, Mary Lou; Quinlivan, Kathleen; Brömdal, Annette; Aspin, Clive

2015-01-01

The broad aim of most sexuality educational programs is to improve and promote health among students (Epstein and Johnson 1998; Allen 2005; Aggleton and Campbell 2000). Various education programs aim for young people to receive preparation for their sexual lives and be educated against sexual abuse and exploitation (Carmody 2009; Bay-Cheng 2003),…

Four Papers on Contemporary Software Design Strategies for Statistical Methodologists

OpenAIRE

Carey, Vincent; Cook, Dianne

2014-01-01

Software design impacts much of statistical analysis and, as technology changes, dramatically so in recent years, it is exciting to learn how statistical software is adapting and changing. This leads to the collection of papers published here, written by John Chambers, Duncan Temple Lang, Michael Lawrence, Martin Morgan, Yihui Xie, Heike Hofmann and Xiaoyue Cheng.

Genetics Home Reference: small fiber neuropathy

Science.gov (United States)

... IS, Cheng X, Han C, Ahn HS, Persson AK, Hoeijmakers JG, Gerrits MM, Pierro T, Lombardi R, Kapetis D, Dib-Hajj SD, Waxman SG. Gain-of-function Nav1.8 mutations in painful neuropathy. Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):19444-9. doi: 10.1073/pnas.1216080109. Epub ...

Characterization and photocatalytic activity of boron-doped TiO2 thin ...

Indian Academy of Sciences (India)

Wintec

Chen Daimai, Wang Dong Yang and Jiang Zhongyi 2006 Ind. Eng. Chem. 45 4110. Cheng Jen-hao 2003 A study on photocatalytic oxidation of aque- ous chlorobenzene solution by nanostructured film of TiO2,. Master Thesis, National Sun Yat-Sen University, Taiwan. Deki S, Henin Yu Yu Ko, Fujita T, Akamatsu K, Mizuhata ...

photoautotrophic, photomixotrophic

African Journals Online (AJOL)

Dion Daniels

on the adaptation of papaya plants, strengthening the function of the stomata and with this, allowing .... culture vessels with a total volume of 250 mL with 30 mL of liquid ..... scaling. Physiological parameters: Chlorophyll a, b and carotenoids. In terms ..... Soluble sugars mediate .... Yu TA, Yeh SD, Cheng YH, Yang JS (2000).

A Comparative Study of Cross-Cultural Gratitude Strategies among Hausa, the Case of Arab and Chinese Students

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Isyaku, Hassan; Yuepeng, Ma; Mahdi, Qusay; Sarhan, Gassan; Salih, Nahid; Paramasivan, Shamala

2016-01-01

The research investigated the thanking/gratitude strategies of three distinct cultures; Hausa, Chinese and Arabic languages with the aim of finding out the different strategies used by them and how different they are in their use of such strategies. The study employs Cheng (2005) Taxonomy of gratitude strategies in analyzing the data which was…

Anatomical studies on the development of Metasequoia glyptostroboides Hu et Cheng wood

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Alina Hejnowicz

2015-01-01

Full Text Available Variability of anatomical characters within a 15 year old stem is presented by the method of contour lines, where against a schematic longitudinal section of a stem points corresponding to the same values for a character are joined by lines, similarly as altitudes in cartography. The method permits prediction of future trends in character changes. It was thus established that tracheid dimensions and diameter of bordered pits in early wood tracheids increase with age of tree and do not reach maximal values before the 15th year. The annual ring width and the height of the rays attain maximal values before the 15th year while the dimensions of ray cells and the percentage of late wood reach almost constant values during the first year or two.

African Journal of Biotechnology - Vol 10, No 51 (2011)

African Journals Online (AJOL)

Advances on research epigenetic change of hybrid and polyploidy in plants · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Z Zhang, J Gao, L Mao, Q Cheng, ZXL Liu, H Lin, Y Shen, M Zhao, C Pan, 10335-10343. http://dx.doi.org/10.5897/AJB10.1893 ...

Analyzing the Behavioral Differences between Students of Different Genders, Prior Knowledge and Learning Performance with an Educational MMORPG: A Longitudinal Case Study in an Elementary School

Science.gov (United States)

Hou, Huei-Tse

2013-01-01

Many researchers have studied the effects of game-based learning (GBL) (eg, Annetta, Minogu, Holmes & Cheng, 2009; Kiili, 2007). However, empirical process analyses of long-term applications of GBL in a school setting are much less common. A process analysis of GBL in a school setting allows us to better understand the role of games in…

Evaluating "Cat Country": The Humor within Satire

Science.gov (United States)

Chang, Chung-chien Karen

2010-01-01

Satire, as a mode, is not frequently employed in Chinese narratives. "Cat Country," or "Mao Cheng Ji," written by Lao She (pen name of Shu Qing Chun, 1898--1966) has come under much attack of its literary values. Whereas most critics have no doubt that this work sets out to satirize China through the portrayal of a society of…

Reference: 418 [Arabidopsis Phenome Database[Archive

Lifescience Database Archive (English)

Full Text Available 418 http://metadb.riken.jp/db/SciNetS_ria224i/cria224u4ria224u16856986i Chai Mao-Feng...cid responses in Arabidopsis. 5 665-74 16856986 2006 Sep The Plant journal An Rui|Chai Mao-Feng|Chen Jia|Chen Qi-Jun|Wang Xue-Chen|Wei Peng-Cheng|Yang Shuhua

Mapping the Terrain of Educational Leadership and Management in East Asia

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Hallinger, Philip; Bryant, Darren

2013-01-01

Purpose: The purpose of this paper is to gain perspective on the extent to which the vision for knowledge production in East Asia set forth by Bajunid, Cheng, Hallinger, Walker, Dimmock and others almost 20 years ago has been fulfilled. The authors undertook an effort to map the terrain of knowledge production in educational leadership and…

Molecular cloning, characterization and expression of WAG-2 ...

Indian Academy of Sciences (India)

China West Normal University, Nanchong, Sichuan 637009, People's Republic of China. Abstract. WAG-2 is a ... tially be extended to rice (Kang et al. 1998 .... Biotechnology (Beijing, China). WAG-2 ... and WAG-2g in M, I and C domains was typically striking, .... Cheng Y., Kato N., Wang W., Li J. and Chen X. 2003 Two RNA.

First Spectroscopic Identification of Pyrocarbonate for High CO2 Flux Membranes Containing Highly Interconnected Three Dimensional Ionic Channels

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2013-01-01

Koura, S. Kohara , K. Takeuchi, S. Takahashi, L. A. Curtiss, M. Grimsditch and M.-L. Saboungi, J. Mol. Struct., 1996, 382, 163–169. 49 L.-J. Chen, X...Cheng, C.-J. Lin and C.-M. Huang, Electrochim. Acta, 2002, 47, 1475–1480. 50 S. Kohara , N. Koura, Y. Idemoto, S. Takahashi, M.-L. Saboungi and L. A

Geochemical distribution of harmful elements in top soils of an Italian National Interest Area (S.I.N.): the Domizio-Flegreo Littoral and Agro Aversano case study

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Bove, M.; Grezzi, G.; Albanese, S.; de Vivo, B.; Lima, A.

2009-04-01

The Domizio-Flegreo Littoral and Agro Aversano area has been classified by the Italian Ministry of Environment (Italian Ministero dell'Ambiente e della Tutela del Territorio e del Mare) as a S.I.N. (Sito di Interesse Nazionale, L. 426/98 - Decreto 10 Gennaio 2000 - G.U. 29/5/01). In this category have been included all those contaminated lands that, both for their extension and their historical and present land use, are considered to be particularly harmful for human health. In Italy have been selected a total of 54 S.I.N.; among all of these, the Domizio-Flegreo Littoral and Agro Aversano S.I.N. is one of the widest (1564 Km2). The study area is located in north-western Campania region, from the Avella Mountain to the coastline, and from the Campi Flegrei area to the northern boundaries between Campania and Latium Regions. It includes a total of 77 towns from both Naples and Caserta provinces. The Domizio-Flegreo Littoral and Agro Aversano S.I.N. is characterized by a strongly urbanization in its internal portions, and by intensive agricultural activities in its northern and coastal portions. During past years this wide area has been the set of an unknown number of illegal activities controlled by the organized crime, including toxic waste disposal of unknown sources from different Regions of Italy, unauthorized building, intensive uncontrolled agricultural practices and so on. Part of these environmental crimes have been and are under investigations by Italian Authorities. For a geochemical characterization of this contaminated land, between May 2006 and January 2008, a total of 292 (179 in the Litorale Domizio-Flegreo and 113 in the Agro Aversano) top soils (5-15 cm depth) have been collected, with a sampling density of about 1 sample/5 Km2. The GIS™ and a new Multifractal Inverse Distance Weighted (MIDW) (Cheng 1999 a; b) method available in the software GeoDAS™ (Cheng, 2003; Lima et al., 2003) interpolated maps have been obtained. The latter are overlaid

Modulation of epithelial sodium channel in human alveolar epithelial ...

African Journals Online (AJOL)

Modulation of epithelial sodium channel in human alveolar epithelial cells by lipoxin A4 through AhR-cAMP-dependent pathway. Bi-Huan Cheng1,2, Li-Wei Pan2, Sheng-Rong Zhang3, Bin-Yu Ying2, Ben-Ji. Wang2, Guo-Liang Lin2 and Shi-Fang Ding1*. 1Department of Critical Care Medicine, Qilu Hospital of Shandong ...

Journal of Genetics | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Genetics. YOU-LIANG ZHENG. Articles written in Journal of Genetics. Volume 92 Issue 1 April 2013 pp 151-154 Research Note. Identification of 40k -secalin genes · Peng-Fei Qi Qing Chen Thérèse Ouellet Cheng-Xing Le Jia Ai Yu-Ming Wei Ji-Rui Wang You-Liang Zheng · More Details Fulltext ...

Systems Biology Approaches for Discovering Biomarkers for Traumatic Brain Injury

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2013-07-01

Canales, R., Cao, X.M., Cebula, T.A., Chen, J.J., Cheng, J., Chu, T.M., Chudin, E., Corson, J., Corton , J.C., Croner, L.J., Davies, C., Davison, T.S...75. Tarca, A.L., Draghici, S., Khatri, P., Hassan, S.S., Mittal, P., Kim, J.S., Kim, C.J., Kusanovic, J.P., and Romero , R. (2009). A novel signaling

An Assessment of China’s Anti-Satellite and Space Warfare Programs, Policies and Doctrines

Science.gov (United States)

2008-01-19

Zhu Rinzhong, “The Theory of GPS and Methods of Countering It,” Junshi xueshu, May 1999, pp. 5859, in Dean Cheng, “The Chinese Space Program: A 21st...Haijun Xueshu Yanjiu 海军学术研究 Military Economics Research Junshi Jingji Yanjiu 军事经济研究 Modern Military Branches Xiandai Bingzhong 现代兵种 Air Force Logistics

Electroactive Polyurea Bearing Oligoaniline Pendants: Electrochromic and Anticorrosive Properties

Science.gov (United States)

2014-12-26

3] Cheng YJ, Yang SH, Hsu CS. Chem Rev 2009;109:5868e923. [4] Gu H, Guo J, Yan X, Wei H, Zhang X, Liu J, et al. Polymer 2014;55:4405e19. [5] Bigg DM...Reddy KN. Modern electrochemistry. New York: John Wiley and Sons; 1976. p. 622. [57] Bockris JOM, Reddy AK. Modern electrochemistry: an introduction to

Expressions of B7-H4 and B7-H3 Proteins and Effect of Sorafenib on ...

African Journals Online (AJOL)

21. Pardoll DM. The blockage of immune checkpoints in cancer immunotherapy. Nat Rev Cancer 2012; 12(4):. 252-264. 22. Wang L, Liu LH, Shan BE. B7-H3: a promising target for tumor immunotherapy. Immunol J 2012; 28(8): 726-729. 23. Liu CZ, Yang KG, Cheng SS. B7-H4: a new negative regulator of T cell immunity.

The γ-gliadin-like γ-prolamin genes in the tribe Triticeae

Indian Academy of Sciences (India)

Supplementary data: The γ-gliadin-like γ-prolamin genes in the tribe Triticeae. Peng-Fei Qi, Cheng-Xing Le, Zhao Wang, Yu-Bin Liu, Qing Chen, Zhen-Zhen Wei, Bin-Jie Xu, Zheng-Yuan Wei,. Shou-Fen Dai, Yu-Ming Wei and You-Liang Zheng. J. Genet. 93, 35–41. Table 1. The γ-prolamin genes of diploid Triticeae species.

Neyman

CERN Document Server

Reid, Constance

1998-01-01

This book is the result of a suggestion made to me by Erich Lehmann of the Department of Statistics of the University of California at Berkeley. Throughout the writing of it I have enjoyed his assistance and companion­ ship and that of his wife, Juliet Shaffer. In the beginning, writing about a man like Neyman, who was alive and still very active, I planned to limit myself to his recollections and records and to my personal observations of him during his eighty-fifth year. It soon became apparent, however, that I would need to supplement these with the recollections of his colleagues and former students. With his consent I consulted them. I am most grateful for the time and effort which so many people expended in talking and writing to me. I would like to mention especially the assistance I received from Lucien Le Cam and Elizabeth Scott and the very friendly cooperation of Egon S. Pearson. Without the latter's careful preservation of Neyman's early letters I would have found it impossible to write in any de...

Influence of carbon nanotube length on toxicity to zebrafish embryos

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Cheng J

2012-07-01

Full Text Available Jinping Cheng,1,2 Shuk Han Cheng11Department of Biology and Chemistry, City University of Hong Kong, Hong Kong; 2State Key Laboratory of Estuarine and Coastal Research, East China Normal University, Shanghai, ChinaAbstract: There is currently a large difference of opinion in nanotoxicology studies of nanomaterials. There is concern about why some studies have indicated that there is strong toxicity, while others have not. In this study, the length of carbon nanotubes greatly affected their toxicity in zebrafish embryos. Multiwalled carbon nanotubes (MWCNTs were sonicated in a nitric acid solution for 24 hours and 48 hours. The modified MWCNTs were tested in early developing zebrafish embryo. MWCNTs prepared with the longer sonication time resulted in severe developmental toxicity; however, the shorter sonication time did not induce any obvious toxicity in the tested developing zebrafish embryos. The cellular and molecular changes of the affected zebrafish embryos were studied and the observed phenotypes scored. This study suggests that length plays an important role in the in vivo toxicity of functionalized CNTs. This study will help in furthering the understanding on current differences in toxicity studies of nanomaterials.Keywords: length, carbon nanotubes, sonication, developmental toxicity, zebrafish

Wind profiler observations on orographic effects of typhoon wind structure modification over Taiwan (120.38 E, 22.6 N)

Energy Technology Data Exchange (ETDEWEB)

Pan, C.J.; Yang, S.S. [National Central Univ., Taiwan (China). Inst. of Space Science; Krishna Reddy, K. [Yogi Vemana Univ., Kadapa (India). Dept. of Physics; Lai, H.C. [Chang Jung Christian Univ., Taiwan (China). Dept. of Engineering and Management Advanced Technology; Wong, C.J. [Universiti Sains Malaysia (Malaysia). School of Physics

2010-07-01

The interaction of the storm circulation with the Central Mountain Range (CMR) of Taiwan is studied with a wind profiler located at the leeside during the invasions of two (Kaemi (200605) and Bopha (200609)) typhoons. The moderate typhoon Kaemi upgraded from a tropical depression on 21 July 2006. It then was made landfall at 15:45 UTC on 24 July 2006 near Cheng-Kung. The weak typhoon Bopha formed at about 12:00 UTC on 5 August 2006 and also landed near Cheng-Kung at around 19:20 UTC on 8 August. A new finding from both typhoons is the vortex splitting into upper and lower parts with the two typhoons that have passed the observation site nearly. For the typhoon Kaemi, demarcation height of the upper-level vortex and lower level is at 2.8 km and passed the site about 3 h earlier than the low-level one. For the typhoon Bopha, the center of the lower-level vortex at 3.5 km locates to the north of the upper-level one at 5.2 km. The re-organization of the split vortexes is found in typhoon Kaemi but not for typhoon Bopha. (orig.)

Wind profiler observations on orographic effects of typhoon wind structure modification over Taiwan (120.38° E, 22.6° N

Directory of Open Access Journals (Sweden)

C. J. Pan

2010-01-01

Full Text Available The interaction of the storm circulation with the Central Mountain Range (CMR of Taiwan is studied with a wind profiler located at the leeside during the invasions of two (Kaemi (200605 and Bopha (200609 typhoons. The moderate typhoon Kaemi upgraded from a tropical depression on 21 July 2006. It then was made landfall at 15:45 UTC on 24 July 2006 near Cheng-Kung. The weak typhoon Bopha formed at about 12:00 UTC on 5 August 2006 and also landed near Cheng-Kung at around 19:20 UTC on 8 August. A new finding from both typhoons is the vortex splitting into upper and lower parts with the two typhoons that have passed the observation site nearly. For the typhoon Kaemi, demarcation height of the upper-level vortex and lower level is at 2.8 km and passed the site about 3 h earlier than the low-level one. For the typhoon Bopha, the center of the lower-level vortex at 3.5 km locates to the north of the upper-level one at 5.2 km. The re-organization of the split vortexes is found in typhoon Kaemi but not for typhoon Bopha.

Comorbidity and confounding factors in attention-deficit/hyperactivity disorder and sleep disorders in children

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Huang YS

2011-09-01

Full Text Available Ya-Wen Jan1,2, Chien-Ming Yang1,3, Yu-Shu Huang4,51Department of Psychology, National Cheng-Chi University, Taipei; 2Sleep Center of Taipei Medical University Hospital, Taipei; 3The Research Center for Mind Brain and Learning, National Cheng-Chi University, Taipei; 4Department of Child Psychiatry and Sleep Center, Chang Gung Memorial Hospital, Taoyuan; 5College of Medicine, Chang Gung University, Taoyuan, TaiwanAbstract: Sleep problems are commonly reported in children with attention-deficit/hyperactivity disorder (ADHD symptoms. Research data regarding the complex and reciprocal relationship between ADHD and sleep disturbances has now accumulated. This paper is focused on the types of sleep problems that are associated with ADHD symptomatology, and attempts to untangle confounding factors and overlapping symptoms. The goal is also to present an updated overview of the pathophysiology of and treatment strategies for sleep problems in children with ADHD. The review also points out that future research will be needed to clarify further the other psychiatric comorbidities and side effects of medication in order to improve treatment outcomes and prevent misdiagnosis in clinical practice.Keywords: attention-deficit/hyperactivity disorder, sleep, children 

Introducing Magneto-Optical Functions into Soft Materials

Science.gov (United States)

2017-05-03

including organic and bio materials by using magnetic nanomaterials. This final report includes the successful developments of magneto-optical... successful developments of magneto-optical properties in both organic and bio magnetic nanocomposites during the project period of three years...proteins on the photoluminescence of nanodiamond. J. Appl . Phys. 2011, 109 (3), 034704. 7, Xu, H.; Hung, C.E.; Cheng, C.L.; Hu, B., Magneto-electric

From Specific Information Extraction to Inferences: A Hierarchical Framework of Graph Comprehension

Science.gov (United States)

2004-09-01

The skill to interpret the information displayed in graphs is so important to have, the National Council of Teachers of Mathematics has created...guidelines to ensure that students learn these skills ( NCTM : Standards for Mathematics , 2003). These guidelines are based primarily on the extraction of...graphical perception. Human Computer Interaction, 8, 353-388. NCTM : Standards for Mathematics . (2003, 2003). Peebles, D., & Cheng, P. C.-H. (2002

Temperature hysteretic effect and its influence on colossal ...

Indian Academy of Sciences (India)

Financial support from IUC-DAEF, Mumbai, India is greatly appreciated. References. [1] G H Rao, J R Sun, J K Liang, W Y Zhou and X R Cheng, Appl. Phys. Lett. 69, 424 (1996). [2] J R Sun, G H Rao, J K Liang and W Y Zhou, Appl. Phys. Lett. 69, 3924 (1996). [3] J Baszynski, J Kovac, A Kowalczyk, J. Magn. Magn. Mater. 195 ...

Computer-aided Human Centric Cyber Situation Awareness

Science.gov (United States)

2016-03-20

in Video, IJCAI: International Joint Conf. on Artificial Intelligence . 16-JUL-11, . : , Kun Sun, Sushil Jajodia, Jason Li, Yi Cheng, Wei Tang...Cyber-Security Conference, June 2015. 2. V.S. Subrahmanian, Invited Speaker, Summer School on Business Intelligence and Big Data Analysis, Capri, Italy... Cybersecurity Conference, Yuval Ne’eman Workshop for Science, Technology and Security, Tel Aviv University, the Israeli National Cyber Bureau, Prime

Nonstationarity RC Workshop Report: Nonstationary Weather Patterns and Extreme Events Informing Design and Planning for Long-Lived Infrastructure

Science.gov (United States)

2017-11-01

discussion at the workshop built on current research in physical climate, hydrology, coastal dynamics/processes, ecology , and environmental risk...train, deploy, and sustain U.S. warfighters and support personnel. In a number of fields, professional codes of ethics and practice have been...model for simulating land use change and assessing vulnerability to flooding.” Ecological Modelling 362(Supplement C): 87-100. Cheng, L. and A

Synthesis of quinoxaline derivatives from terminal alkynes and o ...

Indian Academy of Sciences (India)

Akhil V Nakhate

2017-11-02

Nov 2, 2017 ... Special Issue on Recent Trends in the Design and Development of ... reported Fe3O4@Cu2O supported on the graphene oxide ..... new quinoxaline-based dyes for dye sensitized solar cell .... Zheng L, Cheng X, Yu Y, Xie Y, Li X and Wang Z 2015. Controlled direct growth of Al2O3 -doped HfO2 films on.

Human Resource Slack as an Antecedent to Instilling the Entrepreneurial Mindset within Department of Defense Organizations

Science.gov (United States)

2003-03-01

additional debt or equity capital). Though there has been very little research comparing the three types of slack, Cheng and Kesner found...levels of uncertainty (Evans, 1991; Fiegenbaum and Karnani, 1991; Genus , 1995; Porter, 1980; Sanchez, 1995; Wernerfelt and Karnani; 1984). Firms...Issues 14:68-84. Genus , A. 1995. Flexible Strategic Management. London: Chapman and Hall. Greenley, G.E. and M. Oktemgil. 1998. “A comparison

Neuroleptic malignant syndrome and subsequent clozapine-withdrawal effects in a patient with refractory schizophrenia

OpenAIRE

Cheng, Minfeng; Gu, Huaying; Zheng, Liangrong; Wang, Houliang; Zhong, Zhiyong; Wen, Shenglin

2016-01-01

Minfeng Cheng,* Huaying Gu,* Liangrong Zheng, Houliang Wang, Zhiyong Zhong, Shenglin Wen Department of Psychiatry, Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, People’s Republic of China *These authors contributed equally to this work Abstract: Here, we report a female patient developing neuroleptic malignant syndrome following the use of a combination of clozapine and haloperidol. Subsequently, the patient presented withdrawal effects after an abrupt ...

Cheng et al., Afr J Tradit Complement Altern Med. (2015) 12(4):72 ...

African Journals Online (AJOL)

Proff.Adewunmi

At the advanced stage of hepatic carcinoma, most ... The treatment combination of Chinese medical formula is more in line with the principle for cancer therapy, and studies have shown ... Ciji Hua'ai Baosheng Formula (CHBF) is composed of Dangshen (Radix Codonopsis) 12g (product lot No.130914), Pingbeimu (Bulbus.

Multifractal and Singularity Maps of soil surface moisture distribution derived from 2D image analysis.

Science.gov (United States)

Cumbrera, Ramiro; Millán, Humberto; Martín-Sotoca, Juan Jose; Pérez Soto, Luis; Sanchez, Maria Elena; Tarquis, Ana Maria

2016-04-01

Soil moisture distribution usually presents extreme variation at multiple spatial scales. Image analysis could be a useful tool for investigating these spatial patterns of apparent soil moisture at multiple resolutions. The objectives of the present work were (i) to describe the local scaling of apparent soil moisture distribution and (ii) to define apparent soil moisture patterns from vertical planes of Vertisol pit images. Two soil pits (0.70 m long × 0.60 m width × 0.30 m depth) were excavated on a bare Mazic Pellic Vertisol. One was excavated in April/2011 and the other pit was established in May/2011 after 3 days of a moderate rainfall event. Digital photographs were taken from each Vertisol pit using a Kodak™ digital camera. The mean image size was 1600 × 945 pixels with one physical pixel ≈373 μm of the photographed soil pit. For more details see Cumbrera et al. (2012). Geochemical exploration have found with increasingly interests and benefits of using fractal (power-law) models to characterize geochemical distribution, using the concentration-area (C-A) model (Cheng et al., 1994; Cheng, 2012). This method is based on the singularity maps of a measure that at each point define areas with self-similar properties that are shown in power-law relationships in Concentration-Area plots (C-A method). The C-A method together with the singularity map ("Singularity-CA" method) define thresholds that can be applied to segment the map. We have applied it to each soil image. The results show that, in spite of some computational and practical limitations, image analysis of apparent soil moisture patterns could be used to study the dynamical change of soil moisture sampling in agreement with previous results (Millán et al., 2016). REFERENCES Cheng, Q., Agterberg, F. P. and Ballantyne, S. B. (1994). The separation of geochemical anomalies from background by fractal methods. Journal of Geochemical Exploration, 51, 109-130. Cheng, Q. (2012). Singularity theory and

Variability of glomerular filtration rate estimation equations in elderly Chinese patients with chronic kidney disease

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Liu X

2012-10-01

Full Text Available Xun Liu,1,2,* Mu-hua Cheng,3,* Cheng-gang Shi,1 Cheng Wang,1 Cai-lian Cheng,1 Jin-xia Chen,1 Hua Tang,1 Zhu-jiang Chen,1 Zeng-chun Ye,1 Tan-qi Lou11Division of Nephrology, Department of Internal Medicine, The Third Affiliated Hospital of Sun Yet-sun University, Guangzhou, China; 2College of Biology Engineering, South China University of Technology, Guangzhou, China; 3Department of Nuclear Medicine, The Third Affiliated Hospital of Sun Yet-sun University, Guangzhou, China *These authors contributed equally to this paperBackground: Chronic kidney disease (CKD is recognized worldwide as a public health problem, and its prevalence increases as the population ages. However, the applicability of formulas for estimating the glomerular filtration rate (GFR based on serum creatinine (SC levels in elderly Chinese patients with CKD is limited.Materials and methods: Based on values obtained with the technetium-99m diethylenetriaminepentaacetic acid (99mTc-DTPA renal dynamic imaging method, 319 elderly Chinese patients with CKD were enrolled in this study. Serum creatinine was determined by the enzymatic method. The GFR was estimated using the Cockroft–Gault (CG equation, the Modification of Diet in Renal Disease (MDRD equations, the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI equation, the Jelliffe-1973 equation, and the Hull equation.Results: The median of difference ranged from −0.3–4.3 mL/min/1.73 m2. The interquartile range (IQR of differences ranged from 13.9–17.6 mL/min/1.73 m2. Accuracy with a deviation less than 15% ranged from 27.6%–32.9%. Accuracy with a deviation less than 30% ranged from 53.6%–57.7%. Accuracy with a deviation less than 50% ranged from 74.9%–81.5%. None of the equations had accuracy up to the 70% level with a deviation less than 30% from the standard glomerular filtration rate (sGFR. Bland–Altman analysis demonstrated that the mean difference ranged from −3.0–2.4 mL/min/1.73 m2. However, the

A VLSI-Based High-Performance Raster Image System.

Science.gov (United States)

1986-05-08

and data in broadcast form to the array of memory -hips in the frame buffer, shown in the bottom block. This is simply a physical structure to hold up...Principal Investigator: John Poulton Collaboration on algorithm development: Prof. Jack Goldfeather (Dept. of Mathematics, Carleton Collge ...1983) Cheng-Hong Hsieh (MS, Computer Science, May, 1985) Jeff P. Hultquist Susan Spach Undergraduate ResearLh Assistant: Sonya Holder (BS, Physics , May

2nd International Conference on Intelligent Technologies and Engineering Systems

CERN Document Server

Chen, Cheng-Yi; Yang, Cheng-Fu

2014-01-01

This book includes the original, peer reviewed research papers from the 2nd International Conference on Intelligent Technologies and Engineering Systems (ICITES2013), which took place on December 12-14, 2013 at Cheng Shiu University in Kaohsiung, Taiwan. Topics covered include: laser technology, wireless and mobile networking, lean and agile manufacturing, speech processing, microwave dielectrics, intelligent circuits and systems, 3D graphics, communications, and structure dynamics and control.

Using Eye-Tracking Data and Mouse Cursor Location To Examine Visual Alerting in a Multi-Display Environment

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2014-07-23

displays. Border alerts were similar in width and colour but surrounded the entire perimeter of the display. Secondary task The secondary task...cognitive processes. Cognitive Psychology , 8, 441-480. Li, G., Wang, W., Li, S., Cheng, B., & Green, P. (2014). Effectiveness of flashing brake and hazard...T., Engbert, R., & Henderson, J. (2010). CRISP: A computational model of fixation durations in scene viewing. Psychological Review, 117(2), 382-405

Non-Spherical Gravitational Collapse of Strange Quark Matter

Institute of Scientific and Technical Information of China (English)

Zade S S; Patil K D; Mulkalwar P N

2008-01-01

We study the non-spherical gravitational collapse of the strange quark null fluid.The interesting feature which emerges is that the non-spherical collapse of charged strange quark matter leads to a naked singularity whereas the gravitational collapse of neutral quark matter proceeds to form a black hole.We extend the earlier work of Harko and Cheng[Phys.Lett.A 266 (2000) 249]to the non-spherical case.

Index to Watervliet Arsenal Technical Reports, 1973

Science.gov (United States)

1973-09-01

A TMO IS, (Fir. nem.. middil ineiat, I.-al) Y. F. Cheng6 *°’ ° EPR DAT I..o- , .0, o ,. . , October 1973 47 12 . 0. CONTACTR OMANT .O U. OMGINNATON’S...I) paradox . We could nio anglo of inclination of’ the crack tip to the interfat for ,hi eb the :1 ngnkI it’id the sane order as that of a crack tip

Group Centric Networking: Addressing Information Sharing Requirements at the Tactical Edge

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2016-04-10

Group Centric Networking: Addressing Information Sharing Requirements at the Tactical Edge Bow-Nan Cheng, Greg Kuperman, Patricia Deutsch, Logan...been a large push in the U.S. Department of Defense to move to an all Internet Protocol (IP) infrastructure, particularly on the tactical edge . IP and...lossy links, and scaling to large numbers of users. Unfortunately, these are the exact conditions military tactical edge networks must operate within

Do parents of children with attention-deficit/hyperactivity disorder (ADHD) receive adequate information about the disorder and its treatments? A qualitative investigation

OpenAIRE

Ahmed, Rana; Borst,Jacqueline; Wei,Yong; Aslani,Parisa

2014-01-01

Rana Ahmed,1 Jacqueline M Borst,2 Cheng Wei Yong,3 Parisa Aslani1 1Faculty of Pharmacy, The University of Sydney, Sydney, NSW, Australia; 2Department of Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands; 3School of Pharmacy, The University of Nottingham, Nottingham, UK Background: Attention-deficit/hyperactivity disorder (ADHD) is the most prevalent pediatric neurodevelopmental condition, commonly treated using pharmacological agents such as stimulant medicines. The use o...

Demonstration of Novel Sampling Techniques for Measurement of Turbine Engine Volatile and Non-Volatile Particulate Matter (PM) Emissions

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2017-03-06

WP-201317) Demonstration of Novel Sampling Techniques for Measurement of Turbine Engine Volatile and Non-volatile Particulate Matter (PM... Engine Volatile and Non-Volatile Particulate Matter (PM) Emissions 6. AUTHOR(S) E. Corporan, M. DeWitt, C. Klingshirn, M.D. Cheng, R. Miake-Lye, J. Peck...the performance and viability of two devices to condition aircraft turbine engine exhaust to allow the accurate measurement of total (volatile and non

Direct Bandgap Group IV Materials

Science.gov (United States)

2016-01-21

AFRL-AFOSR-JP-TR-2017-0049 Direct Bandgap group IV Materials Hung Hsiang Cheng NATIONAL TAIWAN UNIVERSITY Final Report 01/21/2016 DISTRIBUTION A...NAME(S) AND ADDRESS(ES) NATIONAL TAIWAN UNIVERSITY 1 ROOSEVELT RD. SEC. 4 TAIPEI CITY, 10617 TW 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING...14. ABSTRACT Direct bandgap group IV materials have been long sought for in both academia and industry for the implementation of photonic devices

Characterization of Microstructure with Low Frequency Electromagnetic Techniques (Preprint)

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2014-02-01

654. 2. G. T. Meaden, Electrical Resistance of Metals, Plenum, New York 1965. 3. G. A. Sargent, K. T. Kinsel, A. L. Pilchak, A. A. Salem , S. L...effect on materials properties. Cambridge university press . 5. Theodoulidis, T., & Kriezis, E. (2005). Series expansions in eddy current nondestructive...analysis, J. Appl . Phys. 89, 2473 (2001). 8. Cheng, D. K., Field and Wave Electromagnetics, Addison-Wiley Publishing Company, Inc., 1989. 9

ROCKS & MINERALS DETERMINATION AND ANALYSIS

Institute of Scientific and Technical Information of China (English)

2015-01-01

20150204 Abaydulla Alimjan(Department of Chemistry and Environmental Sciences,Kashgar Teachers College,Kashgar 844006,China);Cheng Chunying Non-Metallic Element Composition Analysis of Non-Ferrous Metal Ores from Oytagh Town,Xinjiang(Rock and Mineral Analysis,ISSN0254-5357,CN11-2131/TD,33(1),2014,p.44-50,5illus.,4tables,28refs.)Key words:nonferrous metals ore,nonmetals,chemical analysis,thermogravimetric analysis Anions in non-ferrous ore materials

Strongly-Interacting Fermi Gases in Reduced Dimensions

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2015-11-16

12 2012): 0. doi: 10.1103/PhysRevA.86.063625 Allan Adams , Lincoln D Carr, Thomas Schäfer, Peter Steinberg, John E Thomas. Strongly correlated quantum...Physics (NCSU, 2013) Received Book Chapter TOTAL: PERCENT_SUPPORTEDNAME FTE Equivalent: Total Number: Discipline Willie Ong 1.00 Chingyun Cheng 0.50...PERCENT_SUPPORTEDNAME FTE Equivalent: Total Number: NAME Total Number: NAME Total Number: Willie Ong 1 PERCENT_SUPPORTEDNAME FTE Equivalent: Total

Extraction of σ-term from scattering and annihilation channels data

International Nuclear Information System (INIS)

Kuraev, Eh.; Samojlov, V.; Shevchenko, O.; Sisakyan, A.

2001-01-01

The 'dispersion relation on hyperbolas' method by R.Koch, developed for extraction of the chiral symmetry violating σ Nπ -term from the experimental data on the pion-nucleon scattering is applied to estimate σ pb ar p . Two corrections: one arising from nonphysical region of the annihilation channel and the other continuation to the Cheng-Dashen point are taken into account resulting in σ pb ar p (0)=78 MeV

Nonlinear Photonic Systems for V- and W-Band Antenna Remoting Applications

Science.gov (United States)

2016-10-22

AFRL-AFOSR-JP-TR-2016-0088 Nonlinear Photonic Systems for V- and W-Band Antenna Remoting Applications Sheng-Kwang Hwang NATIONAL CHENG KUNG...2016 2. REPORT TYPE Final 3. DATES COVERED (From - To) 26 May 2015 to 25 May 2016 4. TITLE AND SUBTITLE Nonlinear Photonic Systems for V- and W-Band...TERMS nonlinear, photonic , antenna, remote, microwave, amplification, bandwith, modulation 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT SAR

Infrasound Assessment of Infrastructure Report 6: Scour Detection and Riverine Health Assessment Using Infrasound

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2016-05-01

obtained from a soil map of the Ft. Leonard Wood area published by the U.S. Department of Agriculture and National Resources Conservation Service (Larsen...characteristics of two highway bridges with known scour problems in Taiwan . Their research began with finite element (FE) models of a simplified bridge...Washington, DC: United States Department of Agriculture - National Resources Conservation Service. Lee, W., T. T. Cheng, C.H. Chen, and J. Lai

Pharmacological Studies of NOP Receptor Agonists as Novel Analgesics

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2010-05-01

National Institute of Neuroscience, University of Ferrara , 44100 Ferrara , Italy cDepartment of Pharmaceutical Sciences, Biotechnology Center, University of... Ferrara , 44100 Ferrara , Italy dDepartment of Psychology, Institute of Neuroscience, National Cheng-Chi University, Taipei 11605, Taiwana r t i c l e...as described by Arduin et al. [1] at the University of Ferrara , Ferrara , Italy ), morphine sulfate (Mallinckrodt, Hazelwood, MO), (±)J-113397 (1-[3R,4R

Periorbital muscle atrophy associated with topical bimatoprost therapy

OpenAIRE

Wang, Priscilla Xinhui; Koh, Victor Teck Chang; Cheng, Jin Fong

2014-01-01

Priscilla Xinhui Wang, Victor Teck Chang Koh, Jin Fong ChengDepartment of Ophthalmology, National University Health System, SingaporeAbstract: Topical Bimatoprost is a common and popular prostaglandin analog used as an ocular hypotensive agent in the treatment of glaucoma. Side effects include ocular hyperaemia, ocular pruritus, and periocular and iris pigmentary changes. Perioribital lipodystrophy is another well-documented outcome associated with chronic use of topical bimatoprost, which re...

Cognition in the Brain: Investigations Using Positron Emission Tomography

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1992-07-16

0029 DDIRESS (City. State and ZIP Code) 10. SOURCE Of FUNDING NOS. _____________ .dg. 410 PROGRAM PROJECT TASKC WORK .,%r illing Air Force Base, DC...Bethesda, MD 20892 20. Daniel Bubb, M.D. Department of Neurolinguistics Montreal Neurological Institute 15. Sung-cheng tHuang, Ph.D. 3801 University...Chief of Pediatric Neu- rology Service Director, Center for Morphomet- 24. Terry Allard, Ph.D. ric Analysis Cognitive Science Programs Kennedy 9 Office

Antioxidant Capacity and Proanthocyanidin Composition of the Bark of Metasequoia glyptostroboides.

Science.gov (United States)

Chen, Fengyang; Zhang, Lin; Zong, Shuling; Xu, Shifang; Li, Xiaoyu; Ye, Yiping

2014-01-01

Metasequoia glyptostroboides Hu et Cheng is the only living species in the genus Metasequoia Miki ex Hu et Cheng (Taxodiaceae), which is well known as a "living fossil" species. In the Chinese folk medicine, the leaves and bark of M. glyptostroboides are used as antimicrobic, analgesic, and anti-inflammatory drug for dermatic diseases. This study is the first to report the free radical scavenging capacity, antioxidant activity, and proanthocyanidin composition of the bark of M. glyptostroboides. We observed total of six extracts and fractions, which were easily obtained by water-ethanol extraction and followed by a further separation with D101 resin column chromatography, had significant DPPH radical, superoxide anion radical, and hydroxyl radical scavenging capacity, total antioxidative capacity (T-AOC), lipid peroxidation inhibitory activity, and metal ions chelating capacity. The fraction MGEB, which was obtained by 60% ethanol extraction and followed by a further separation with D101 resin column chromatograph, possessed the highest proanthocyanidin content and the highest free radical scavenging and antioxidant activities. Furthermore, MGEB could significantly protect against CCl4 induced acute liver injury through inhibition of oxidative stress in mice. In addition, ten proanthocyanidins were isolated from MGEB, and six of them were firstly reported from this plant.

Antioxidant Capacity and Proanthocyanidin Composition of the Bark of Metasequoia glyptostroboides

Directory of Open Access Journals (Sweden)

Fengyang Chen

2014-01-01

Full Text Available Metasequoia glyptostroboides Hu et Cheng is the only living species in the genus Metasequoia Miki ex Hu et Cheng (Taxodiaceae, which is well known as a “living fossil” species. In the Chinese folk medicine, the leaves and bark of M. glyptostroboides are used as antimicrobic, analgesic, and anti-inflammatory drug for dermatic diseases. This study is the first to report the free radical scavenging capacity, antioxidant activity, and proanthocyanidin composition of the bark of M. glyptostroboides. We observed total of six extracts and fractions, which were easily obtained by water-ethanol extraction and followed by a further separation with D101 resin column chromatography, had significant DPPH radical, superoxide anion radical, and hydroxyl radical scavenging capacity, total antioxidative capacity (T-AOC, lipid peroxidation inhibitory activity, and metal ions chelating capacity. The fraction MGEB, which was obtained by 60% ethanol extraction and followed by a further separation with D101 resin column chromatograph, possessed the highest proanthocyanidin content and the highest free radical scavenging and antioxidant activities. Furthermore, MGEB could significantly protect against CCl4 induced acute liver injury through inhibition of oxidative stress in mice. In addition, ten proanthocyanidins were isolated from MGEB, and six of them were firstly reported from this plant.

Comparison of Amount of Primary Tooth Reduction Required for Anterior and Posterior Zirconia and Stainless Steel Crowns.

Science.gov (United States)

Clark, Larkin; Wells, Martha H; Harris, Edward F; Lou, Jennifer

2016-01-01

To determine if aggressiveness of primary tooth preparation varied among different brands of zirconia and stainless steel (SSC) crowns. One hundred primary typodont teeth were divided into five groups (10 posterior and 10 anterior) and assigned to: Cheng Crowns (CC); EZ Pedo (EZP); Kinder Krowns (KKZ); NuSmile (NSZ); and SSC. Teeth were prepared, and assigned crowns were fitted. Teeth were weighed prior to and after preparation. Weight changes served as a surrogate measure of tooth reduction. Analysis of variance showed a significant difference in tooth reduction among brand/type for both the anterior and posterior. Tukey's honest significant difference test (HSD), when applied to anterior data, revealed that SSCs required significantly less tooth removal compared to the composite of the four zirconia brands, which showed no significant difference among them. Tukey's HSD test, applied to posterior data, revealed that CC required significantly greater removal of crown structure, while EZP, KKZ, and NSZ were statistically equivalent, and SSCs required significantly less removal. Zirconia crowns required more tooth reduction than stainless steel crowns for primary anterior and posterior teeth. Tooth reduction for anterior zirconia crowns was equivalent among brands. For posterior teeth, reduction for three brands (EZ Pedo, Kinder Krowns, NuSmile) did not differ, while Cheng Crowns required more reduction.

The Role of SIRT1 In Breast Cancer Stem Cells

Science.gov (United States)

2016-09-01

2009;9:123-8. 56. Ma W, Xiao GG, Mao J, Lu Y, Song B, Wang L, Fan S, Fan P, Hou Z, Li J, Yu X, 20 Wang B, Wang H, Wang H, Xu F, Li Y, Liu Q, Li L...Int J Biol Sci. 2010;6:599-612. 63. Zhang Y, Zhang M, Dong H, Yong S, Li X, Olashaw N, Kruk PA, Cheng JQ, Bai W, Chen J, Nicosia SV, Zhang X

Percutaneous kyphoplasty combined with zoledronic acid infusion in the treatment of osteoporotic thoracolumbar fractures in the elderly

OpenAIRE

Shi,Chen; Zhang,Mi; Cheng,An-Yuan; Huang,Zi-Feng

2018-01-01

Chen Shi,1,* Mi Zhang,2,* An-Yuan Cheng,1 Zi-Feng Huang1 1Department of Trauma Surgery, Wuhan No 1 Hospital, Wuhan, China; 2Department of Orthopedics, Wuhan No 5 Hospital, Wuhan, China *These authors contributed equally to this work Objective: We studied the efficacy of zoledronic acid (ZOL) infusion on radiographic and clinical outcomes after percutaneous kyphoplasty (PKP) for elderly patients with osteoporotic thoracolumbar fractures (osteoporotic vertebral compression fractures...

Percutaneous kyphoplasty combined with zoledronic acid infusion in the treatment of osteoporotic thoracolumbar fractures in the elderly

OpenAIRE

Shi C; Zhang M; Cheng AY; Huang ZF

2018-01-01

Chen Shi,1,* Mi Zhang,2,* An-Yuan Cheng,1 Zi-Feng Huang1 1Department of Trauma Surgery, Wuhan No 1 Hospital, Wuhan, China; 2Department of Orthopedics, Wuhan No 5 Hospital, Wuhan, China *These authors contributed equally to this work Objective: We studied the efficacy of zoledronic acid (ZOL) infusion on radiographic and clinical outcomes after percutaneous kyphoplasty (PKP) for elderly patients with osteoporotic thoracolumbar fractures (osteoporotic vertebral compression fractures [OV...

Stabilizing Protein Effects on the Pressure Sensitivity of Fluorescent Gold Nanoclusters

Science.gov (United States)

2016-01-13

affected by the environment of the stabilizing protein, allowing these hybrid systems to act as sensors in many applications.2,9,14–19 This has led...Biosens Bioelectron. 2012;32:297–299. 8. Joseph D, Geckeler KE. Synthesis of highly fluorescent gold nanoclusters using egg white proteins. Colloids Surf...Chang HW, Chien YC, Hsiao JK, Cheng JT, Chou PT. Insulin -directed synthesis of fluorescent gold nanoclusters: preservation of insulin bioactivity and

Water reclamation for aquifer recharge at the eight case study sites: a cross case analysis

CSIR Research Space (South Africa)

Le Corre, K

2012-06-01

Full Text Available , Tredoux, Gideon, Wintgens, Thomas, Cheng Xuzhou, Yu, Liang and Zhao, Xuan Abstract: Water scarcity combined with the quality deterioration of freshwater due to the rapid augmentation of population and industrial development is a major concern... stream_source_info Genthe_2012_ABSTRACT.pdf.txt stream_content_type text/plain stream_size 1118 Content-Encoding ISO-8859-1 stream_name Genthe_2012_ABSTRACT.pdf.txt Content-Type text/plain; charset=ISO-8859-1 Water...

Network Intrusion Dataset Assessment

Science.gov (United States)

2013-03-01

International Conference on Computational Intelligence and Natural Computing, volume 2, pages 413–416, June 2009. • Rung Ching Chen, Kai -Fan Cheng, and...Chia-Fen Hsieh . “Using rough set and support vector machine for network intrusion detection.” International Journal of Network Security & Its...intrusion detection using FP tree rules.” Journal Of Advanced Networking and Applications, 1(1):30–39, 2009. • Ming-Yang Su, Gwo-Jong Yu , and Chun-Yuen

Cost and Performance Report: Solar-Powered Remediation and pH Control

Science.gov (United States)

2017-04-01

parallel, with two batteries in each series, providing a 24 V DC power supply. A solar charge controller regulated the charging of the batteries when...ER-201033) Solar -Powered Remediation and pH Control April 2017 This document has been cleared for public release; Distribution Statement A...Technol. 32:1817-1824. CB&I Federal Services. 2017. Final Report. Solar Powered Remediation and pH Control . ESTCP Project ER-201033. April. Cheng, S

Novel Combinatory Approaches to Repair Visual System after Optic Nerve Damage

Science.gov (United States)

2014-09-01

Novel Combinatory Approaches to Repair Visual System After Optic Nerve Damage 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6...biological functions such as metabolism, growth, cell cycle, and survival ( Cardone et al., 1998; Diehl, Cheng, Roussel, & Sherr, 1998; Hers, Vincent...of injured adult sensory neurons. The Journal of Neuroscience, 21, 7161–7170. Cardone , M. H., Roy, N., Stennicke, H. R., Salvesen, G. S., Franke, T. F

Sustained release of vancomycin from novel biodegradable nanofiber-loaded vascular prosthetic grafts: in vitro and in vivo study

OpenAIRE

Liu, Kuo-Sheng; Lee, Cheng-Hung; Wang, Yi-Chuan; Liu, Shih-Jung

2015-01-01

Kuo-Sheng Liu,1 Cheng-Hung Lee,2 Yi-Chuan Wang,3 Shih-Jung Liu3 1Department of Thoracic and Cardiovascular Surgery, Chang Gung Memorial Hospital, Linkou, Taiwan; 2Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Linkou, Taiwan; 3Department of Mechanical Engineering, Chang Gung University, Tao-Yuan, Taiwan Abstract: This study describes novel biodegradable, drug-eluting nanofiber-loaded vascular prosthetic grafts that provide local and sustained...

Biomarkers in the Detection of Prostate Cancer in African Americans

Science.gov (United States)

2015-09-01

Eds. L Cheng, D. Zhang, Eble J), Springer Science+ Business Media. 2013;483-497. K. Bledsoe MJ, Grizzle WE. Use of Human Tissue in Research: The...Alternatively, one can use the bootstrap method to test for model instability (38-39). Clinical events: A clinical event is defined as the least...problems, and suggested solutions. Caner Treat Rep 1985;69:1071-1077. 38. Efron B. Bootstrap methods: Another look at the jackknife. Ann. Statist

A facile method to prepare superparamagnetic iron oxide and hydrophobic drug-encapsulated biodegradable polyurethane nanoparticles

OpenAIRE

Cheng,Kuo-Wei; Hsu,Shan-hui

2017-01-01

Kuo-Wei Cheng, Shan-hui Hsu Institute of Polymer Science and Engineering, College of Engineering, National Taiwan University, Taipei, Taiwan, Republic of China Abstract: Superparamagnetic iron oxide nanoparticles (SPIO NPs) have a wide range of biomedical applications such as in magnetic resonance imaging, targeting, and hyperthermia therapy. Aggregation of SPIO NPs can occur because of the hydrophobic surface and high surface energy of SPIO NPs. Here, we developed a facile method to encaps...

Molecular Signatures and Diagnostic Biomarkers of Cumulative, Blast-Graded Mild TBI

Science.gov (United States)

2013-10-01

ischemic stroke. Neurol. Res. 30, 783–793. 35. Wang, H.C., Lin, W.C., Lin, Y.J., Rau, C.S., Lee, T.H., Chang, W.N., Tsai, N.W., Cheng, B.C., Kung , C.T., and...J.K., Shen, C.A., Yin, H.N., Zhou, X.F., Lu, W., Hu, Q.G., Chi, Y.F., Ma, L., 22  Deng, H.P., Zhang, X.B., Sun, T.J., and Han , Y.F. (2010). [Early

Judeus no Brasil Imperial: uma pesquisa nos Documentos e Noticiário Carioca da Época

Directory of Open Access Journals (Sweden)

Frida Flaksberg

1977-09-01

Full Text Available WOLFF, Egon e Frieda. Judeus no Brasil Imperial: uma pesquisa nos Documentos e Noticiário Carioca da Época. São Paulo: Centro de Estudos Judaicos da Universidade de São Paulo, 1975. No 1. 549 pp. (4a. parágrafo do texto Esta obra tem como meta o levantamento de fontes para o estudo dos judeus no Brasil Imperial. Ela apresenta um caráter inédito o qual pode ser apreendido nas próprias palavras do Prof. Dr. Eurípedes Simões de Paula:  "o caráter inédito dos trabalhos consiste justamente no fato de que o período do nosso Império ainda não foi até agora devidamente estudado sob o ângulo da presença dos judeus e sua participação social e econômica naquele período. É importante e necessário era que se fizesse antes de tudo uma avaliação básica das fontes disponíveis para os futuros estudiosos".

Impacts of elevated ozone on growth and photosynthesis of Metasequoia glyptostroboides Hu et Cheng.

Science.gov (United States)

Zhang, Weiwei; Feng, Zhaozhong; Wang, Xiaoke; Niu, Junfeng

2014-09-01

One-year-old Metasequoia glyptostroboides seedlings were exposed to non-filtered ambient air (NF) and elevated ozone (E-O3, NF+60 ppb) in open-top chambers for two years. E-O3 accelerated leaf senescence, as indicated by significant decreases in photosynthetic pigment contents with the elongation of O3 exposure. E-O3 significantly affected gas exchange and carboxylation, inducing reductions in light-saturated photosynthesis (Asat), the maximum activity of Rubisco (Vc,max) and the maximum electron transport rate (Jmax). Chl a/b, Vc,max/Jmax and stomatal limitation (l) were not affected. Stomatal conductance (gs) was significantly decreased by E-O3 in the first year, but remained unchanged in the second year. It can be inferred that the decrease in Asat by E-O3 was mainly attributed to the changes in non-stomatal factors. After two years' exposure, E-O3 caused significant decreases in canopy photosynthesis and leaf mass per area, and a significant increase in the number of branches, but induced slight, not significant decreases in growth and biomass. Therefore, it can be concluded that the carbon accumulation of the species M. glyptostroboides could be negatively affected after long-term exposure to high O3 concentration. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Temporal and spatial characteristics of male cone development in Metasequoia glyptostroboides Hu et Cheng.

Science.gov (United States)

Jin, Biao; Tang, Liang; Lu, Yan; Wang, Di; Zhang, Min; Ma, Jiuxia

2012-12-01

Metasequoia glyptostroboides, a famous relic species of conifer that survived in China, has been successfully planted in large numbers across the world. However, limited information on male cone development in the species is available. In this study, we observed the morphological and anatomical changes that occur during male cone development in M. glyptostroboides using semi-thin sections and scanning electron microscopy. The male cones were borne oppositely on one-year-old twigs that were mainly located around the outer and sunlit parts of crown. Male cones were initiated from early September and shed pollen in the following February. Each cone consisted of spirally arranged microsporophylls subtended by decussate sterile scales, and each microsporophyll commonly consisted of three microsporangia and a phylloclade. The microsporangial wall was composed of an epidermis, endothecium, and tapetum. In mid-February, the endothecium and tapetum layers disintegrated, and in the epidermal layer the cell walls were thickened with inner protrusions. Subsequently, dehiscence of the microsporangia occurred through rupturing of the microsporangial wall along the dehiscence line. These results suggest that the structure, morphology, architecture and arrangement of male cones of M. glyptostroboides are mainly associated with the production, protection and dispersal of pollen for optimization of wind pollination.

Knowledge gained from analyzing mercury speciation data monitored in North America

Science.gov (United States)

Zhang, L.; Cheng, I.; Gay, D. A.; Xu, X.; Wu, Z.

2017-12-01

This presentation summarizes knowledge gained in several recent studies through analysis and application of mercury (Hg) speciation data monitored in North America. Annual Hg dry deposition to vegetated surfaces in the rural or remote environment in North America was dominated by leaf uptake of gaseous elemental mercury (GEM), contrary to what was commonly assumed in earlier studies which frequently omitted GEM dry deposition as an important process (Zhang et al., EST, 2016). Dry deposition exceeded wet deposition by a large margin in all of the seasons except in the summer at the majority of the sites. Based on the gaseous oxidized mercury (GOM) concentrations predicted from measured Hg wet deposition using a scavenging ratio method, multi-year average GOM concentrations collected using Tekran speciation instrument were likely biased low by a factor of 2 at about half of the studied sites (Cheng and Zhang, EST, 2017). A decline in the number of source regions impacting ambient GEM and GOM was found from 2005-2014 at an eastern U.S. site through concentration-weighted trajectory (CWT) analysis (Cheng et al., JAS, 2017). Source contributions decreased by up to 20% for GEM, greater than 60% for GOM, and 20-60% for PBM in 2011-2014 than in 2006-2008, largely due to power plant Hg emission reductions since 2009. A study comparing Positive Matrix Factorization (PMF) and Principal Components Analysis (PCA) receptor methods identified similar sources impacting Kejimkujik National Park, Canada, including combustion, industrial sulfur, photochemistry and re-emissions, and oceanic sea-salt emissions. Improving the quality of the Hg data used in receptor methods by imputation did not improve the PMF results, but reducing the fraction of below detection limit data was effective (Xu et al., ACP, 2017). PCA results using reactive mercury (RM=GOM+PBM) or excluding low GOM values were similar to those using the original data. Source contributions from CWT analysis were more

Novel Quantum States with Exotic Spin Properties - Unconventional Generalization of Magnetism

Science.gov (United States)

2011-12-30

including journal references, in the following categories: PaperReceived Wei-Cheng Lee, D. P. Arovas, Congjun Wu. Quasiparticle interference in the...Zhang. Quasiparticle interference on the surface of the topological insulator Bi2Te3, Physical Review B, (12 2009): . doi: 2010/01/29 14:52:09 7 W... quasiparticle excitations. A successful observation of such mode will be a demonstration of the completion between s± and dx2−y2 pairings. 4.2

Novel Therapy for Bone Regeneration in Large Segmental Defects

Science.gov (United States)

2014-10-01

detailed bone analysis (and the majority of blood biochemistries will be completed together at the end of the study), the bulk of our findings will be...resume care for the first 48 hours as preferred by our large animal veterinarian. This brings us to 4p Friday afternoon at which time Dr. Cheng, our...postdoctoral fellow, and the combination of medical students split coverage from 4p Friday evening until 8a Monday morning for the post-operative

Consumer Perception towards Brand Slogans:An investigative study towards Consumer Perception in the Malaysian Automobile Industry

OpenAIRE

Sharjeel, Syed Muhammad

2007-01-01

This dissertation focuses on the concerned attribute of brand which would be the primary investigative entity of this dissertation; brand expression/ brand message/ brand tagline/brand slogan. Brand slogans are exploited as a marketing tool to facilitate message diffusion among the consumer market, as well as a powerful tool for targeted segment’s brand positioning (Cheng et al, 2006). In our every day lives, we come across hundreds of brands with several brand slogans targeting at different...

A systematic review and meta-analysis of Harmonic technology compared with conventional techniques in mastectomy and breast-conserving surgery with lymphadenectomy for breast cancer

OpenAIRE

Clymer, Jeffrey; Cheng,Hang; Ferko,Nicole; Patel,Leena; Soleas,Ireena M; Cameron,Chris G; Hinoul,Piet

2016-01-01

Hang Cheng,1 Jeffrey W Clymer,1 Nicole C Ferko,2 Leena Patel,2 Ireena M Soleas,2 Chris G Cameron,2 Piet Hinoul1 1Ethicon Inc., Cincinnati, OH, USA; 2Cornerstone Research Group, Burlington, ON, Canada Background: Mastectomy and breast-conserving surgery (BCS) are important treatment options for breast cancer patients. A previous meta-analysis demonstrated that the risk of certain complications can be reduced with the Harmonic technology compared with conventional methods in mastectomy. However...

Comparison of generation 3 polyamidoamine dendrimer and generation 4 polypropylenimine dendrimer on drug loading, complex structure, release behavior, and cytotoxicity

OpenAIRE

Cheng, Yiyung; Shao,; Zhang ,; Hu,; Zhang,; Zhang,

2011-01-01

Naimin Shao1, Yunzhang Su1, Jingjing Hu2, Jiahai Zhang3, Hongfeng Zhang1, Yiyun Cheng1,41School of Life Sciences, East China Normal University, Shanghai, 2CAS Key Laboratory of Soft Matter Chemistry, Department of Chemistry, University of Science and Technology of China, Hefei,  3School of Life Sciences, University of Science and Technology of China, Hefei, 4Shanghai Key Laboratory of Magnetic Resonance, Department of Physics, East China Normal University, Shanghai, ChinaBackground: ...

The People’s Liberation Army and China in Transition

Science.gov (United States)

2003-08-01

Chinese only. See “ Zhong - shan Daxue Diaocha Xianshi: Qi Cheng Xuetong Ji Ju Zhengdang Pian Hao” (“Sun Yat-sen University Poll shows 70 percent of...uneventfully to seats of power in Beijing . Hu became both state president and CCP general secretary. Yet the third generation of leaders, led by...geostrategic claims along China’s periphery. ■ Even as the war on terrorism has created a new context in which Washington and Beijing could begin

Sustained release of bactericidal concentrations of penicillin in the pleural space via an antibiotic-eluting pigtail catheter coated with electrospun nanofibers: results from in vivo and in vitro studies

OpenAIRE

Chao, Yin-Kai; Lee, Cheng-Hung; Liu, Kuo-Sheng; Wang, Yi-Chuan; Wang, Chih-Wei; Liu, Shih-Jung

2015-01-01

Yin-Kai Chao,1 Cheng-Hung Lee,2 Kuo-Sheng Liu,1 Yi-Chuan Wang,3 Chih-Wei Wang,4 Shih-Jung Liu3 1Department of Thoracic and Cardiovascular Surgery, Chang Gung Memorial Hospital-Linkou, College of Medicine, Chang Gung University, Taoyuan, Taiwan; 2Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital-Linkou, College of Medicine, Chang Gung University, Taoyuan, Taiwan; 3Department of Mechanical Engineering, Chang Gung University, Taoyuan, Taiwan; 4Department of P...

Long-term results of a randomized controlled trial evaluating preoperative chemotherapy in resectable non-small cell lung cancer

OpenAIRE

Chen, Zhiwei; Luo, Qingquan; Jian, Hong; Zhou, Zhen; Cheng, Baijun; Lu, Shun; Liao, Meilin

2013-01-01

Zhiwei Chen,* Qingquan Luo,* Hong Jian, Zhen Zhou, Baijun Cheng, Shun Lu, Meilin LiaoShanghai Lung Tumor Clinical Medical Center, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, People’s Republic of China *These authors contributed equallyObjective: We aimed to evaluate whether preoperative chemotherapy provides benefits in the survival and prognosis of patients with non-small cell lung cancer (NSCLC) in resectable stages I to IIIA, except T1N0. Methods: In this ra...

Pion--nucleon sigma-commutator

International Nuclear Information System (INIS)

Banerjee, M.K.; Cammarata, J.B.

1977-07-01

The reasons for the large discrepancies in the magnitude of the πN sigma-commutator, sigma(πN), obtained by several authors are discussed using dynamic theory of the πN scattering amplitude. With sigma(πN) approximately 25 MeV this theory reproduces reasonably well both the experimental S-wave phase shifts at low energies and the amplitudes C approximately/sup(+)/(ν=0,t less than or equal to 0) determined by Langbein. In the method of Cheng and Dashen the value of sigma(πN) is obtained from these amplitudes by extrapolation to t = 2m 2 /sub π/. A study of the experimental D-wave ''scattering lengths'' implies that the coefficient of the term quadratic in t in the Hoehler expansion of C approximately/sup(+)/(0,t) is negative. Adding such a term to the results of the S-wave theory will tend to improve the agreement for C approximately/sup (+)/(0,t less than or equal to 0). These results suggest that the large ''world value'' sigma(πN) = 65 +- 5 MeV obtained using the Cheng-Dashen method is a consequence of errors in the extrapolation of amplitudes to the unphysical point ν = 0, t = 2m 2 /sub π/. Only the smaller value sigma(πN) approximately 25 MeV appears to be consistent with the experimental data and theoretical constraints

Spinning droplets: non-first generation East and Southeast Asian Australian poets and the discourse of water

OpenAIRE

McFarlane, Rosalind Nicole

2017-01-01

Poetry written by diasporic Asian groups in Australia has been gaining increasing attention, especially with the 2013 release of Contemporary Asian Australian Poets edited by Adam Aitken, Kim Cheng Boey and Michelle Cahill, the first anthology of this kind of work. This thesis aims to be the first instance of sustained critical attention paid to many of the poets included in this anthology, including Adam Aitken, Ivy Alvarez, Lachlan Brown, Lily Chan, Bella Li, Debbie Lim, Miriam Wei Wei Lo, ...

The absent father of Sino-French cinema: Contemporary Taiwanese cinema and 1950s French auteurs

OpenAIRE

Bloom, ME

2014-01-01

© 2014 Taylor & Francis. In contemporary Sino-French cinema, father characters who are dead, long lost or geographically distant leave gaping holes in the lives of the offspring left behind. The absent fathers in Sino-French films by Taiwanese auteurs Cheng Yu-chieh, Hou Hsiao-hsien and Tsai Ming-liang serve as metaphors for French auteurs. French New Wave films constitute the majority of the intertexts; however, early 1950s French cinema and even late nineteenth-century painting reflect th...

Molecular grading of tumors of the upper urothelial tract using FGFR3 mutation status identifies patients with favorable prognosis

OpenAIRE

Fernandez, Cecilia; Lyle,Stephen; Hsieh,; Shuber,Anthony

2012-01-01

Stephen R Lyle,1 Chung-Cheng Hsieh,1 Cecilia A Fernandez,2 Anthony P Shuber21University of Massachusetts, Worcester, MA, 2Predictive Biosciences Inc., Lexington, MA, USABackground: Mutations in FGFR3 have been shown to occur in tumors of the upper urothelial tract and may be indicative of a good prognosis. In bladder tumors, the combination of FGFR3 mutation status and Ki-67 level has been used to define a tumor's molecular grade and predict survival. Pathological evaluation of upper ...

Music therapy-induced changes in salivary cortisol level are predictive of cardiovascular mortality in patients under maintenance hemodialysis

OpenAIRE

Hou, Yi-Chou; Lin, Yen-Ju; Lu, Kuo-Cheng; Chiang, Han-Sun; Chang, Chia-Chi; Yang, Li-King

2017-01-01

Yi-Chou Hou,1 Yen-Ju Lin,2 Kuo-Cheng Lu,1 Han-Sun Chiang,3 Chia-Chi Chang,4 Li-King Yang1 1Department of Internal Medicine, Cardinal Tien Hospital, School of Medicine, Fu-Jen Catholic University, 2Department of Nursing, Taipei Medical University, 3Graduate Institute of Basic Medicine, College of Medicine, Fu Jen Catholic University, New Taipei City, 4School of Gerontology Health Management, College of Nursing, Taipei Medical University, Taipei, Taiwan, Republic of China Background:...

Materials Research Society Symposium Proceedings. Volume 723. Molecularly Imprinted Materials - Sensors and Other Devices. Symposia Held in San Francisco, California on April 2-5, 2002

Science.gov (United States)

2002-04-05

Ana Rego for the XPS measurements. This work was supported by the Fundaqo para a Ciencia e Tecnologia (FCT) through their POCTI program (#: 34022/99). F...Buchheit, H. Kahn, 2002, ISBN: 1-55899-623-0 Volume 688- Ferroelectric Thin Films X, S.R. Gilbert, Y . Miyasaka, D. Wouters, S. Trolier-McKinstry...Surface Engineering 2001--Fundamentals and Applications, W.J. Meng, A. Kumar, Y -W. Chung, G.L. Doll, Y -T. Cheng, S. Veprek, 2002, ISBN: 1-55899-633-8 Volume

Proteomic Analysis to Identify Functional Molecules in Drug Resistance Caused by E-Cadherin Knockdown in 3D-Cultured Colorectal Cancer Models

Science.gov (United States)

2013-09-01

of human MCF10A cells. Proteomics 2011, 11 (10), 2019−26. (23) Siu, S. O.; Lam , M. P.; Lau , E.; Kong, R. P.; Lee, S. M.; Chu, I. K. Fully automatable...signaling. J. Proteome Res. 2011, 10 (12), 5383−97. (17) Kettenbach, A. N .; Gerber, S. A. Rapid and reproducible single- stage phosphopeptide enrichment of...McGowan, T.; Bandhakavi, S.; Cheng, B.; Rhodus, N . L.; Griffin, T. J. Large-scale phosphoproteomics Journal of Proteome Research Article dx.doi.org

Wide Band-Gap Semiconductors. 1991 Materials Research Society Symposium Proceedings

Science.gov (United States)

1992-09-01

ORIGIN OF POLYTYPES IN SiC AND ZnS 507 Volker Heine, C. Cheng, G.E. Engel, and R.I. Needs EPITAXIAL MONOCRYSTALLINE SiC FILMS GROWN ON Si BY LOW...carbon film component. INTRODUCTION One of the most challenging problems in diamond film research has been the growth of high quality, monocrystalline ...developing ZnS EL full color flat panel displays is that the insufficient intensity of blue light emission ( two orders of magnitude lower than that of red

MicroRNAs in Prostate Cancer

Science.gov (United States)

2008-11-01

lymphoma. Genes Chromosom. Cancer 39:167–69 131. O’Connell RM, Taganov KD, Boldin MP, Cheng G, Baltimore D. 2007. MicroRNA-155 is induced during the...carcinoma. J. Virol. 81:1033–36 155. Xi Y, Nakajima G, Gavin E, Morris CG, Kudo K, et al. 2007. Systematic analysis of microRNA expression of RNA extracted ...diversity. miRNAs were extracted from the unique sequences by searching against miRNA database (miRbase release 10.0; http://microrna.sanger.ac.uk

Evaluation of existing correlations for the prediction of pressure drop in wire-wrapped hexagonal array pin bundles

International Nuclear Information System (INIS)

Chen, S.K.; Todreas, N.E.; Nguyen, N.T.

2014-01-01

Highlights: • Wire-wrapped bundle friction factor data and correlations thoroughly collected. • Three methodologies proposed for identifying the best fit correlation. • 80 out of 141 bundles selected as database for evaluation. • The detailed Cheng and Todreas correlation identified to fit the data best. - Abstract: Existing wire-wrapped fuel bundle friction factor correlations were evaluated to identify their comparative fit to the available pressure drop experimental data. Five published correlations, those of Rehme (REH), Baxi and Dalle Donne (BDD, which used the correlations of Novendstern in the turbulent regime and Engel et al. in the laminar and transition regimes), detailed Cheng and Todreas (CTD), simplified Cheng and Todreas (CTS), and Kirillov (KIR, developed by Russian scientists) were studied. Other correlations applicable to a specific case were also evaluated but only for that case. Among all 132 available bundle data, an 80 bundle data set was judged to be appropriate for this evaluation. Three methodologies, i.e., the Prediction Error Distribution, Agreement Index and Credit Score were principally used for investigating the goodness of each correlation in fitting the data. Evaluations have been performed in two categories: 4 cases of general user interest and 3 cases of designer specific interest. The four general user interest cases analyzed bundle data sets in four flow regimes – i.e., all regimes, the transition and/or turbulent regimes, the turbulent regime, and the laminar regime. The three designer interest cases analyzed bundles in the fuel group, the blanket and control group and those with P/D > 1.06, for the transition/turbulent regimes. For all these cases, the detailed Cheng and Todreas correlation is identified as yielding the best fit. Specifically for the all flow regimes evaluation, the best fit correlation in descending order is CTD, BDD/CTS (tie), REH and KIR. For the combined transition/turbulent regime, the order is

Reversal of multidrug resistance by magnetic Fe3O4 nanoparticle copolymerizating daunorubicin and 5-bromotetrandrine in xenograft nude-mice

OpenAIRE

Chen, Baoan

2009-01-01

Baoan Chen1,* Jian Cheng1,* Yanan Wu1, Feng Gao1, Wenlin Xu2, et al 1Department of Hematology;2Department of Hematology, The Affiliated People’s Hospital, Jiangsu University, Zhenjiang, PR China *These authors have contributed equally to this workAbstract: In this paper we establish the xenograft leukemia model with stable multidrug resistance in nude mice and to investigate the reversal effect of 5-bromotetrandrine (5-BrTet) and magnetic nanoparticle of Fe3O4 (MNP-Fe3O4) c...

Functionally Graded Material: An overview

CSIR Research Space (South Africa)

Mahamood, RM

2012-07-01

Full Text Available -3146. [50] X. Jin, L. Wu, L. Guo, H. Yu, and Y. Sun, ?Experimental investigation of the mixed-mode crack propagation in ZrO2/NiCr functionally graded materials,? Engineering Fracture Mechanics, vol. 76(12), (2009), pp. 1800-1810. [51] Z. Cheng, D. Gao... by stable crack growth,? Engineering Fracture Mechanics, vol.72(15), (2005), pp. 2359-2372. [47] Z.-H. Jin, and R.H. Dodds Jr, ?Crack growth resistance behavior of a functionally graded material: computational studies,? Engineering Fracture Mechanics...

Decadal and long-term sea level variability in the tropical Indo-Pacific Ocean

Digital Repository Service at National Institute of Oceanography (India)

Nidheesh, A.G.; Lengaigne, M.; Vialard, J.; Unnikrishnan, A.S.; Dayan, H.

(Shankar and Shetye 1999, Unnikrishnan and Shankar 2007) as well as in the basin scale (Lee and McPhaden 2008, Cheng et al. 2008, Han et al. 2010) have been previously investigated, the picture of decadal/multi-decadal variability in the tropical Indo... dynamics along the rim of the northern Indian Ocean (McCreary et al. 1993, McCreary et al. 1996). At intra- seasonal timescales, the Indo-Pacific warm pool region is home to the Madden-Julian Oscillation, an eastward moving energetic fluctuation of deep...

The potential of acidophilic macroalgae as part of passive bioremediation technology for acid mine drainage in constructed wetlands

CSIR Research Space (South Africa)

Cheng, Po-Hsun

2012-10-01

Full Text Available macroalgae as part of passive bioremediation technology for acid mine drainage in constructed wetlands PH CHENG1,3, PJ OBERHOLSTER1,2, A-M BOTHA3 1CSIR Natural Resources and the Environment, PO Box 320, Stellenbosch, 7599, South Africa 2Department... of diverse benthic algal species to AMD provides the option to utilise them in AMD remediation as part of passive bioremediation technology in constructed wetlands. The purpose of the study was to investigate the bioaccumulation of metals and trace metal...

The demographic revolution and our common future: quo vadimus?

Directory of Open Access Journals (Sweden)

Egon Diczfalusy

2007-03-01

Full Text Available Professor Egon Diczfalusy reflects on a lifetime of experience, drawing insights from not only the great masters of the arts, philosophy and the sciences but also from a time in history in which he has witnessed some of the greatest triumphs in science as well as some of the greatest tragedies against humanity. This paper highlights some of the most pressing public health issues facing the world today, such as population growth and the changing global population structure, examining factors such as longevity and the progressive imbalance between the number of elderly persons in our communities and the number of persons who are able to support them. Finally he discusses the falling rates in fertility, stressing its multifactorial aetiology. In his closing remarks he poses three major problems that face the scientific community today. The use and misuse of science The growing discrepancy between scientific development and our moral/ethical development. The need to convince todays and future generations that fanatic faith, fundamentalism and obscurantism will not improve the quality of life of their children and grandchildren. His final reflections remind us that we belong to a humanistic science one in which we should not only strive to achieve the wisdom of humility but also the wisdom of hope.

Mixing of t2 g-eg orbitals in 4 d and 5 d transition metal oxides

Science.gov (United States)

Stamokostas, Georgios L.; Fiete, Gregory A.

2018-02-01

Using exact diagonalization, we study the spin-orbit coupling and interaction-induced mixing between t2 g and egd -orbital states in a cubic crystalline environment, as commonly occurs in transition metal oxides. We make a direct comparison with the widely used t2 g-only or eg-only models, depending on electronic filling. We consider all electron fillings of the d shell and compute the total magnetic moment, the spin, the occupancy of each orbital, and the effective spin-orbit coupling strength (renormalized through interaction effects) in terms of the bare interaction parameters, spin-orbit coupling, and crystal-field splitting, focusing on the parameter ranges relevant to 4 d and 5 d transition metal oxides. In various limits, we provide perturbative results consistent with our numerical calculations. We find that the t2 g-eg mixing can be large, with up to 20% occupation of orbitals that are nominally "empty," which has experimental implications for the interpretation of the branching ratio in experiments, and can impact the effective local moment Hamiltonian used to study magnetic phases and magnetic excitations in transition metal oxides. Our results can aid the theoretical interpretation of experiments on these materials, which often fall in a regime of intermediate coupling with respect to electron-electron interactions.

Pretreatment combination of platelet counts and neutrophil–lymphocyte ratio predicts survival of nasopharyngeal cancer patients receiving intensity-modulated radiotherapy

Directory of Open Access Journals (Sweden)

Lin YH

2017-05-01

Full Text Available Yu-Hsuan Lin,1 Kuo-Ping Chang,2 Yaoh-Shiang Lin,2,3 Ting-Shou Chang2–4 1Department of Otolaryngology, Head and Neck Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, 2Department of Otolaryngology, Head and Neck Surgery, Kaohsiung Veterans General Hospital, Kaohsiung, 3Department of Otolaryngology, Head and Neck Surgery, National Defense Medical Center, Taipei, 4Institute of Public Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan, Republic of China Background: Increased cancer-related inflammation has been associated with unfavorable clinical outcomes. The combination of platelet count and neutrophil–lymphocyte ratio (COP-NLR has related outcomes in several cancers, except for nasopharyngeal carcinoma (NPC. This study evaluated the prognostic value of COP-NLR in predicting outcome in NPC patients treated with intensity-modulated radiotherapy (IMRT.Materials and methods: We analyzed the data collected from 232 NPC patients. Pretreatment total platelet counts, neutrophil–lymphocyte ratio (NLR, and COP-NLR score were evaluated as potential predictors. Optimal cutoff values for NLR and platelets were determined using receiver operating curve. Patients with both elevated NLR (>3 and platelet counts (>300×109/L were assigned a COP-NLR score of 2; those with one elevated or no elevated value were assigned a COP-NLR a score of 1 or 0. Cox proportional hazards model was used to test the association of these factors and relevant 3-year survivals.Results: Patients (COP-NLR scores 1 and 2=85; score 0=147 were followed up for 55.19 months. Univariate analysis showed no association between pretreatment NLR >2.23 and platelet counts >290.5×109/L and worse outcomes. Multivariate analysis revealed that those with COP-NLR scores of 0 had better 3-year disease-specific survival (P=0.02, overall survival (P=0.024, locoregional relapse-free survival (P=0.004, and distant

Delivery of a survivin promoter-driven antisense survivin-expressing plasmid DNA as a cancer therapeutic: a proof-of-concept study

Directory of Open Access Journals (Sweden)

Lin KY

2016-05-01

Full Text Available Kun-Yuan Lin,1 Siao Muk Cheng,2 Shing-Ling Tsai,2 Ju-Ya Tsai,1 Chun-Hui Lin,1 Chun Hei Antonio Cheung1,2 1Department of Pharmacology, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC; 2Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC Abstract: Survivin is a member of the inhibitor-of-apoptosis proteins family. It is overexpressed in many different cancer types but not in the differentiated normal tissue. In addition, overexpression of survivin promotes cancer cell survival and induces chemotherapeutic drug resistance, making it an attractive target for new anticancer interventions. Despite survivin being a promising molecular target for anticancer treatment, it is widely accepted that survivin is only a “semi-druggable” target. Therefore, it is important to develop a new strategy to target survivin for anticancer treatment. In this study, we constructed a novel survivin promoter-driven full-length antisense survivin (pSur/AS-Sur expression plasmid DNA. Promoter activity assay revealed that the activity of the survivin promoter of pSur/AS-Sur correlated with the endogenous expression of survivin at the transcriptional level in the transfected A549, MDA-MB-231, and PANC-1 cancer cells. Western blot analysis showed that liposomal delivery of pSur/AS-Sur successfully downregulated the expression of survivin in A549, MBA-MB-231, and PANC-1 cells in vitro. In addition, delivery of pSur/AS-Sur induced autophagy, caspase-dependent apoptosis, and caspase-independent apoptosis as indicated by the increased LC3B-II conversion, autophagosome formation, caspase-9/-3 and poly(ADP-ribose polymerase-1 cleavage, and apoptosis-inducing factor nuclear translocation in A549, MBA-MB-231, and PANC-1 cells. Importantly, liposomal delivery of pSur/AS-Sur was also capable of decreasing the proliferation of the survivin/MDR1 coexpressing multidrug-resistant KB-TAX50 cancer cells and

Perturbative ambiguities in Coulomb gauge QCD

International Nuclear Information System (INIS)

Doust, P.

1987-01-01

The naive Coulomb gauge Feynman rules in non-abelian gauge theory give rise to ambiguous integrals, in addition to the usual ultraviolet divergences. Generalizing the work of Cheng and Tsai, these ambiguities are resolved to all orders in perturbation theory, by defining a gauge that interpolates smoothly between the Feynman gauge and the Coulomb gauge. The extra terms V 1 +V 2 of Christ and Lee are identified with certain two-loop ambiguous terms. However, there still seem to be unsolved problems connected with renormalisation. copyright 1987 Academic Press, Inc

Identification of Genes Differentially Expressed During Heat Shock Treatment in Aedes aegypti

Science.gov (United States)

2009-01-01

Chan, C. W. Cheng, and R. S. Wu. 2003. Cloning of theHSP70 gene in barnacle larvae and its expression under hypoxic conditions. Mar. Pollut. Bull. 46...665Ð671. Chuang, K. H., S. H. Ho, and Y. L. Song. 2007. Cloning and expression analysis of heat shock cognate 70 gene pro- moter in tiger shrimp ...in larvae , but not adults, of a polar insect. Proc. Natl. Acad. Sci. U.S.A. 103: 14223Ð14227. Robich, R. M., J. P. Rinehart, L. J. Kitchen, and D. L

Ökodisainist futuristlike tudengite silmade läbi

Index Scriptorium Estoniae

2007-01-01

Electroluxi Design Lab'i 2007. a. ülemaailsel disainivõistlusel Pariisis kujundasid tootedisaini üliõpilased keskkonnasõbralikke kodumasinaid aastaks 2020. Tutvustatakse finaliste: pesumasin E-wash (I koht - Levente Szabo), päikeseenergial töötav toiduvalmistaja Pebble (II - Laura Pandelle), kärjekujulistest sahtlitest koosnev külmik Go Fresh (III - He Cheng Fei), õhupuhastaja Nature Wind (Bae Won-Ho), plastikut kodustes tingimustes lagundav seade Return Pot (Juan Ying-Hao), nõudepesumasin Pure Washer (Tatjana Voronova), ududushsh Fog Shower (Joao Diego Schimansky), kompostiseade Circompo (Thanat Tengamnuay)

Towards HIV detection: Novel Poly(propylene imine) Dendrimer-Streptavidin platform for electrochemical DNA and gp120 aptamer biosensors

CSIR Research Space (South Africa)

John, SV

2014-07-01

Full Text Available to thank Mr Anton of the Laser Research Laboratory, University of Johannesburg for laboratory assistance. References 1. S. Tombelli, M. Minunni, E. Luzi and M. Mascini, Bioelectrochemistry, 67 (2005) 135 2. O. C. Farokhzad, J. Cheng, B. A. Teply..., I. Sherifi, S. Jon, P. W. Kantoff, J. P. Richie and R. Langer, Proc Natl Acad Sci U S A, 103 (2006) 6315 3. E. W. Orava, A. Abdul-Wahidb, E. H.-B. Huang, A. I. Mallick and J. Gariépya, Molecular Oncology, 7 (2013) 799 4. S. Tombelli, M. Minunni...

Polyurethane Binder Systems for Polymer Bonded Explosives

Science.gov (United States)

2006-12-01

Propulsion (2005), Santiago , Chile . 8. Huang, C.-C., Hwu, W.-H., Cheng, C.-S., Shyy, I.-N., and Yang, K.-K., Study on Thermal Decomposition of Composite...water or amines to form ureas (Figure 2). R NCO R N C O H+ H2O O H R NH2 - CO2 R NCO R N C O NR’ H H ureaamine Figure 2. Reaction of an isocyanate...Monoisocyanates are present as impurities in low concentration in most diisocyanates. Table 1. Common diisocyanates Isocyanate Structure B.p. (ºC

Indian summer monsoon and winter hydrographic variations over past millennia resolved by clay sedimentation

Digital Repository Service at National Institute of Oceanography (India)

Chauhan, O.S.; Dayal, A.M.; Basavaiah, N.; Kader, U.S.A.

the eastern Arabian Sea, Earth planet. Sci. Lett., 177, 209-218, doi:10.1016/S0012-821X(00)00053-4. Sinha, A., K. G. Cannariato, L. D. Stott, H. Cheng, R. L. Edwards, M. G. Yadava, R. Ramesh, and I. B. Singh (2007), A 900-year (600 to 1500 A.D.) record.../1 (# 3904; latitude 08 o 07.9’ N; Longitude 76 o 01.8’ E; water depth 1400 m; Figure 1) has been chosen for the present study, because: (i) it lies in an area receiving orographically enhanced SWM precipitation, (ii) located in advection path of BBW...

3rd International Conference on Intelligent Technologies and Engineering Systems

CERN Document Server

2016-01-01

This book includes the original, peer reviewed research from the 3rd International Conference on Intelligent Technologies and Engineering Systems (ICITES2014), held in December, 2014 at Cheng Shiu University in Kaohsiung, Taiwan. Topics covered include: Automation and robotics, fiber optics and laser technologies, network and communication systems, micro and nano technologies, and solar and power systems. This book also Explores emerging technologies and their application in a broad range of engineering disciplines Examines fiber optics and laser technologies Covers biomedical, electrical, industrial, and mechanical systems Discusses multimedia systems and applications, computer vision and image & video signal processing.

Bi-Force

DEFF Research Database (Denmark)

Sun, Peng; Speicher, Nora K; Röttger, Richard

2014-01-01

of pairwise similarities. We first evaluated the power of Bi-Force to solve dedicated bicluster editing problems by comparing Bi-Force with two existing algorithms in the BiCluE software package. We then followed a biclustering evaluation protocol in a recent review paper from Eren et al. (2013) (A...... comparative analysis of biclustering algorithms for gene expressiondata. Brief. Bioinform., 14:279-292.) and compared Bi-Force against eight existing tools: FABIA, QUBIC, Cheng and Church, Plaid, BiMax, Spectral, xMOTIFs and ISA. To this end, a suite of synthetic datasets as well as nine large gene expression...

Preface to the Special Issue on "Connection of Solar and Heliospheric Activities with Near-Earth Space Weather: Sun-Earth Connection"

Directory of Open Access Journals (Sweden)

Chin-Chun Wu Sunny W. Y. Tam

2013-01-01

Full Text Available This special issue of the Terrestrial, Atmospheric and Oceanic Sciences (TAO presents a small collection of the materials presented at the 2011 International Space Plasma Symposium (ISPS, held at National Cheng-Kung University (NCKU in Tainan, Taiwan, Republic of China (ROC, from August 15 - 19, 2011. The purpose of the Symposium was to bring space physicists together to present their recent research results and discuss some outstanding questions in, but not limited to, the solar corona, interplanetary medium, planetary magnetosphere and ionospheres. A total number of 59 papers were presented at the Symposium by scientists from 11 countries and regions.

Lifetime risks, loss of life expectancy, and health care expenditures for 19 types of cancer in Taiwan

Directory of Open Access Journals (Sweden)

Wu TY

2018-05-01

Full Text Available Tzu-Yi Wu,1 Chia-Hua Chung,2 Chia-Ni Lin,3 Jing-Shiang Hwang,2 Jung-Der Wang3,4 1Institute of Economics, Academia Sinica, Taipei, Taiwan; 2Institute of Statistical Science, Academia Sinica, Taipei, Taiwan; 3Department of Public Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan; 4Department of Occupational and Environmental Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan Background: The mortality rates for different cancers are no longer an efficient tool for making national policy. The purpose of this study were to quantify the lifetime risks, life expectancies (LEs after diagnosis, expected years of life lost (EYLL, and lifetime health care expenditures for 19 major cancers in Taiwan. Methods: A total of 831,314 patients with 19 pathologically proven cancers were abstracted from the Taiwan Cancer Registry from 1998 to 2012. They were linked to the National Mortality Registry (1998–2014 and National Health Insurance reimbursement database (1998–2013 for survival and health care costs. We estimated the cumulative incidence rate for ages 0–79 years and the lifetime survival function for patients with different cancer sites. The EYLL was calculated by subtracting the LE of each cancer cohort from that of the age- and sex-matched referents simulated from national life tables. The estimated lifetime cost was calculated by adding up the product of survival probability and mean cost at the corresponding duration-to-date after adjustment for the inflation to the year of 2013. Results: There were 5 cancers with a lifetime risk exceeding 4%: colorectal, liver, lung, and prostate in males, and breast and colorectal in females. Cancers with EYLL of >10 years were: esophageal, intrahepatic bile ducts, liver, pancreas, oral, nasopharyngeal, leukemia, lung, and gallbladder, extrahepatic bile ducts and biliary tract in males, and intrahepatic bile ducts

Effects of traditional and cyber homophobic bullying in childhood on depression, anxiety, and physical pain in emerging adulthood and the moderating effects of social support among gay and bisexual men in Taiwan

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Wang CC

2018-05-01

Full Text Available Chien-Chuan Wang,1,2 Huang-Chi Lin,2,3 Mu-Hong Chen,4,5 Nai-Ying Ko,6,7 Yu-Ping Chang,8 I-Mei Lin,9 Cheng-Fang Yen2,3 1Zuoying Branch of Kaohsiung Armed Forces General Hospital, Kaohsiung, Taiwan; 2Department of Psychiatry, Graduate Institute of Medicine and Department of Psychiatry, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; 3Department of Psychiatry, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan; 4Division of Child and Adolescent Psychiatry, Department of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan; 5Department of Psychiatry, College of Medicine, National Yang-Ming University, Taipei, Taiwan; 6Department of Nursing, College of Medicine, National Cheng Kung University, Tainan, Taiwan; 7Nursing Department and Center for Infection Control, National Cheng Kung University Hospital, Tainan, Taiwan; 8School of Nursing, The State University of New York, University at Buffalo, Buffalo, NY, USA; 9Department of Psychology, College of Humanities and Social Science, Kaohsiung Medical University, Kaohsiung, Taiwan Objective: This study examined the differences in the current levels of depression, anxiety, and physical pain in emerging adulthood among gay and bisexual men with various experiences of traditional and cyber homophobic bullying based on gender role nonconformity and sexual orientation and the moderating effects of family and peer support.Methods: A total of 500 gay or bisexual men (age 20–25 years in Taiwan were recruited from August 2015 to July 2017. The levels of depression, anxiety, and physical pain among gay or bisexual men who had experienced both traditional and cyber homophobic bullying (n=109, only traditional or cyber bullying (n=173, and neither traditional nor cyber bullying during childhood (n=218 were compared. The moderating effects of family and peer support on the effects of homophobic bullying victimization on depression, anxiety, and physical pain

Selecting score types for longitudinal evaluations: the responsiveness of the Comprehensive Developmental Inventory for Infants and Toddlers in children with developmental disabilities

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Tsai YP

2016-05-01

Full Text Available Yu-Pei Tsai,1,2 Li-Chen Tung,1,3 Ya-Chen Lee,4 Yu-Lin Wang,1,5 Yun-Shan Yen,1 Kuan-Lin Chen4,6 1Department of Physical Medicine and Rehabilitation, Chi-Mei Medical Center, Tainan, 2Department of Special Education, National Chiayi University, Chiayi, 3School of Medicine, Chung Shan Medical University, Taichung, 4Department of Occupational Therapy, College of Medicine, National Cheng Kung University, 5Department of Sports Management, Chia Nan University of Pharmacy and Science, 6Department of Physical Medicine and Rehabilitation, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan Objective: The objective of this study was to examine the responsiveness of the Comprehensive Developmental Inventory for Infants and Toddlers (CDIIT in children with developmental disabilities (DD.Methods: The responsiveness of a measure is its ability to detect change over time, and it is fundamental to an outcome measure for detecting changes over time. We compared the responsiveness of four types of scores (ie, raw scores, developmental ages [DAs], percentile ranks [PRs], and developmental quotients [DQs] in the five subtests of the CDIIT. The CDIIT was administrated three times at intervals of 3 months on 32 children with DD aged between 5 months and 64 months (mean =30.6, standard deviation [SD] =17.8. The CDIIT is a pediatric norm-referenced assessment commonly used for clinical diagnosis of developmental delays in five developmental areas: cognition, language, motor, social, and self-care skills. The responsiveness was analyzed using three methods: effect size, standardized response mean, and paired t-test.Results: The effect size results showed that at the 3-month and 6-month follow-ups, responsiveness was small or moderate in the raw scores and DAs of most of the subtest scores of the CDIIT, but the level of responsiveness varied in the PRs and DQs. The standardized response mean results of the 3-month

Study on Adaptive Parameter Determination of Cluster Analysis in Urban Management Cases

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Fu, J. Y.; Jing, C. F.; Du, M. Y.; Fu, Y. L.; Dai, P. P.

2017-09-01

The fine management for cities is the important way to realize the smart city. The data mining which uses spatial clustering analysis for urban management cases can be used in the evaluation of urban public facilities deployment, and support the policy decisions, and also provides technical support for the fine management of the city. Aiming at the problem that DBSCAN algorithm which is based on the density-clustering can not realize parameter adaptive determination, this paper proposed the optimizing method of parameter adaptive determination based on the spatial analysis. Firstly, making analysis of the function Ripley's K for the data set to realize adaptive determination of global parameter MinPts, which means setting the maximum aggregation scale as the range of data clustering. Calculating every point object's highest frequency K value in the range of Eps which uses K-D tree and setting it as the value of clustering density to realize the adaptive determination of global parameter MinPts. Then, the R language was used to optimize the above process to accomplish the precise clustering of typical urban management cases. The experimental results based on the typical case of urban management in XiCheng district of Beijing shows that: The new DBSCAN clustering algorithm this paper presents takes full account of the data's spatial and statistical characteristic which has obvious clustering feature, and has a better applicability and high quality. The results of the study are not only helpful for the formulation of urban management policies and the allocation of urban management supervisors in XiCheng District of Beijing, but also to other cities and related fields.

STUDY ON ADAPTIVE PARAMETER DETERMINATION OF CLUSTER ANALYSIS IN URBAN MANAGEMENT CASES

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J. Y. Fu

2017-09-01

Full Text Available The fine management for cities is the important way to realize the smart city. The data mining which uses spatial clustering analysis for urban management cases can be used in the evaluation of urban public facilities deployment, and support the policy decisions, and also provides technical support for the fine management of the city. Aiming at the problem that DBSCAN algorithm which is based on the density-clustering can not realize parameter adaptive determination, this paper proposed the optimizing method of parameter adaptive determination based on the spatial analysis. Firstly, making analysis of the function Ripley's K for the data set to realize adaptive determination of global parameter MinPts, which means setting the maximum aggregation scale as the range of data clustering. Calculating every point object’s highest frequency K value in the range of Eps which uses K-D tree and setting it as the value of clustering density to realize the adaptive determination of global parameter MinPts. Then, the R language was used to optimize the above process to accomplish the precise clustering of typical urban management cases. The experimental results based on the typical case of urban management in XiCheng district of Beijing shows that: The new DBSCAN clustering algorithm this paper presents takes full account of the data’s spatial and statistical characteristic which has obvious clustering feature, and has a better applicability and high quality. The results of the study are not only helpful for the formulation of urban management policies and the allocation of urban management supervisors in XiCheng District of Beijing, but also to other cities and related fields.

Tests of the power PC theory of causal induction with negative contingencies.

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Shanks, David R

2002-01-01

The power PC theory of causal induction (Cheng, 1997) proposes that causal estimates are based on the power p of a potential cause, where p is the contingency between the cause and effect normalized by the base rate of the effect. Previous tests of this theory have concentrated on generative causes that have positive contingencies with their associated outcomes. Here we empirically test this theory in two experiments using preventive causes that have negative contingencies for their outcomes. Contrary to the power PC theory, the results show that causal judgments vary with contingency across conditions of constant power p. This pattern is consistent, however, with several alternative accounts of causal judgment.

Research summer camp in photonics

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Buyanovskaya, Elizaveta; Melnik, Maksim; Egorov, Vladimir; Gleim, Artur; Lukishova, Svetlana; Kozlov, Sergei; Zhang, Xi-Cheng

2017-08-01

ITMO University and the University of Rochester became close partners several years ago. One of the first outcomes of this mutually beneficial partnership was the creation of International Institute of Photonics and Optical Information Technologies led by Prof. Sergei Kozlov and Prof. Xi-Cheng Zhang. Universities have created a double Masters-degree program in optics in 2014, and several ITMO students have been awarded degrees from Rochester. At the same time ITMO University organizes Summer Research camp in Photonics for University of Rochester students. Students spent two weeks in the Northern Capital of Russia learning about the emerging practical applications of femtosecond optics, terahertz biomedicine and quantum information technologies.

X ray microanalysis of leaf and seed elemental composition among four species of living fossil gymnosperm

International Nuclear Information System (INIS)

Chang Chongyan; Li Yongliang; Chen Xiaoduan; Liu Jinying; Zhou Yunlong

2002-01-01

The leaf and seed elemental composition and average mass fraction are analysed or four species of living fossil gymnosperm: Ginkgo biloba L., Cathaya argyrophylla Chun et Kuang, Glyptostrobus pensilis (D. Don) Koch and Metasequoia glyptostroboides Hu et Cheng by SEM X ray microanalysis method. The results show that the elemental composition is different and the elemental average mass fraction is evidently different between the seed and leaf for the same species. The elemental composition and average mass fraction between seed and seed wing is different in Cathaya argyrophylla and Metasequoia glyptostroboides. Among three type leaf of Glyptostrobus pensilis, the elemental composition is the same, but average mass fraction is very different

Chaos synchronization of a new chaotic system via nonlinear control

International Nuclear Information System (INIS)

Zhang Qunjiao; Lu Junan

2008-01-01

This paper investigates chaos synchronization of a new chaotic system [Lue J, Chen G, Cheng D. A new chaotic system and beyond: the generalized Lorenz-like system. Int J Bifurcat Chaos 2004;14:1507-37]. Two kinds of novel nonlinear controllers are designed based on the Lyapunov stability theory. It can be viewed as an improvement to the existing results of reference [Park JH. Chaos synchronization of a chaotic system via nonlinear control. Chaos, Solitons and Fractals 2005;25:579-84] because we use less controllers but realize a global and exponential asymptotical synchronization. Numerical simulations are provided to show the effectiveness and advantage of this method

Analysis of the static yield stress for giant electrorheological fluids

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Seo, Youngwook P.; Choi, Hyoung Jin; Seo, Yongsok

2017-08-01

Cheng et al. (2010)'s experimental results for the static yield stress of giant electrorheological (GER) fluids over the full range of electric field strengths were reanalyzed by applying Seo's scaling function which could include both the polarization and the conductivity models. The Seo's scaling function could correctly fit the yield stress behavior of GER suspensions behavior after if a proper normalization of the yield stress data was taken which collapse them onto a single curve. The model predictions were also contrasted with recently proposed Choi et al.'s scaling function to rouse the attention for a proper consideration of the GER fluid mechanisms.

Records of new and rare elasmobranchs from Taiwan.

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Hsu, Hua Hsun; Joung, Shoou Jeng; Ebert, David A; Lin, Chia Yen

2013-01-01

Five new records of elasmobranchs collected from eastern Taiwan fish markets, Da-xi and Cheng-gong, are presented. Samples were caught by deepsea longliners and bottom trawlers which operate in northeastern waters off Taiwan between 2004 and 2012. These five new species records include the smalltooth sandtiger, Odontaspis ferox (Risso, 1810) (Lamniformes: Odontaspididae), salamander shark, Parmaturus pilosus Garman, 1906 (Carcharhiniformes: Scyliorhinidae), leadhued skate Notoraja tobitukai (Hiyama, 1940) (Rajiformes: Arhynchobatidae), giant skate Dipturus gigas (Ishiyama, 1958) (Rajiformes: Rajidae), and the pelagic stingray Pteroplatytrygon violacea (Bonaparte, 1832) (Myliobatiformes: Dasyatidae), Diagnostic characteristics for each species are given and a key to the genera Parmaturus and Dipturus from Taiwan is presented.

Neuroleptic malignant syndrome and subsequent clozapine-withdrawal effects in a patient with refractory schizophrenia

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Cheng MF

2016-03-01

Full Text Available Minfeng Cheng,* Huaying Gu,* Liangrong Zheng, Houliang Wang, Zhiyong Zhong, Shenglin Wen Department of Psychiatry, Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, People’s Republic of China *These authors contributed equally to this work Abstract: Here, we report a female patient developing neuroleptic malignant syndrome following the use of a combination of clozapine and haloperidol. Subsequently, the patient presented withdrawal effects after an abrupt discontinuation of clozapine. Psychiatrists not aware of possible clozapine-withdrawal effects may misdiagnose as a part of the primary mental illness or as the initial symptoms worsening, if unrecognized. Keywords: clozapine, neuroleptic malignant syndrome, withdrawal effect, schizophrenia

Micropropagação do porta-enxerto de macieira 'Seleção 69' tolerante à podridão do colo (Phytophthora cactorum Micropropagation of 'Seleção 69' apple rootstock tolerant the rotting (Phytophthora cactorum

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Claudete Santa-Catarina

2001-10-01

Full Text Available A utilização de porta-enxertos anões, tolerantes a problemas fitossanitários da cultura da macieira, como a podridão do colo (Phytophthora cactorum, pode aumentar o rendimento e reduzir os custos de produção. Com o presente trabalho, objetivou-se estabelecer um protocolo de micropropagação do porta-enxerto 'Seleção 69', tolerante à podridão do colo. Ápices meristemáticos foram cultivados in vitro em meio de cultura MS, suplementado com 4,4mM de 6-Benzilaminopurina (BAP, 2,5mM de Ácido indolbutírico (AIB, 0,3mM de Ácido giberélico (GA3, 3% de sacarose e 0,6% de ágar. Foram testados o efeito da concentração de BAP (2,2 e 4,4mM e o efeito dos meios de cultura (MS, Cheng e Quoirin & Lepoivre na multiplicação das brotações. No alongamento das brotações, foram testados os efeitos do GA3 (0; 0,5; 1,0 e 1,5mM e AIB (0; 0,5 e 1,0mM. Para a fase de enraizamento ex vitro e aclimatização, foram testadas diferentes concentrações de AIB (0; 1 e 2g L-1. A taxa de desenvolvimento dos ápices meristemáticos cultivados in vitro foi de 30%. Para estimular a brotação, a melhor concentração de BAP foi 2,2mM, a qual proporcionou 2,6 brotações por explante. O meio MS proporcionou o maior número de brotações por explante (2,5, porém não diferiu estatisticamente do meio Cheng (2,0 brotações por explante. Para a fase de alongamento, o meio MS suplementado com 2,2mM de BAP e 1,0mM de AIB, proporcionou a maior altura das brotações (23mm. Na fase de enraizamento ex vitro e aclimatização, as concentrações de 0, 1 e 2g L-1 de AIB possibilitaram em média, 77,3% de enraizamento das microestacas.The use of tolerant apple rootstocks to phytossanitary problems as the rotting (Phytophthora cactorum is able to increase the production with cost reduction. The objective of the present study is to establish in vitro micropropagation protocol of the '69 Selection' rootstocks tolerant to the rotting. Meristems was cultivated in vitro

Acceleration Modes and Transitions in Pulsed Plasma Accelerators

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Polzin, Kurt A.; Greve, Christine M.

2018-01-01

accelerators was developed by Cheng, et al. The Coaxial High ENerGy (CHENG) thruster operated on the 10-microseconds timescales of pulsed plasma thrusters, but claimed high thrust density, high efficiency and low electrode erosion rates, which are more consistent with the deflagration mode of acceleration. Separate work on gas-fed pulsed plasma thrusters (PPTs) by Ziemer, et al. identified two separate regimes of performance. The regime at higher mass bits (termed Mode I in that work) possessed relatively constant thrust efficiency (ratio of jet kinetic energy to input electrical energy) as a function of mass bit. In the second regime at very low mass bits (termed Mode II), the efficiency increased with decreasing mass bit. Work by Poehlmann et al. and by Sitaraman and Raja sought to understand the performance of the CHENG thruster and the Mode I / Mode II performance in PPTs by modeling the acceleration using the Hugoniot Relation, with the detonation and deflagration modes representing two distinct sets of solutions to the relevant conservation laws. These works studied the proposal that, depending upon the values of the various controllable parameters, the accelerator would operate in either the detonation or deflagration mode. In the present work, we propose a variation on the explanation for the differences in performance between the various pulsed plasma accelerators. Instead of treating the accelerator as if it were only operating in one mode or the other during a pulse, we model the initial stage of the discharge in all cases as an accelerating current sheet (detonation mode). If the current sheet reaches the exit of the accelerator before the discharge is completed, the acceleration mode transitions to the deflagration mode type found in the quasi-steady MPD thrusters. This modeling method is used to demonstrate that standard gas-fed pulsed plasma accelerators, the CHENG thruster, and the quasi-steady MPD accelerator are variations of the same device, with the overall

Novel targeted nuclear imaging agent for gastric cancer diagnosis: glucose-regulated protein 78 binding peptide-guided 111In-labeled polymeric micelles

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Cheng CC

2013-04-01

Full Text Available Chun-Chia Cheng,1,2,* Chiung-Fang Huang,3,4,* Ai-Sheng Ho,5 Cheng-Liang Peng,6 Chun-Chao Chang,7,8 Fu-Der Mai,1,9 Ling-Yun Chen,10 Tsai-Yueh Luo,2 Jungshan Chang1,11,121Graduate Institute of Medical Sciences, Taipei Medical University, Taipei, 2Institute of Nuclear Energy Research, Atomic Energy Council, Taoyuan, 3School of Dental Technology, Taipei Medical University, Taipei, 4Division of Family and Operative Dentistry, Department of Dentistry, Taipei Medical University Hospital, Taipei, 5Division of Gastroenterology, Cheng Hsin General Hospital, Taipei, 6Institute of Biomedical Engineering, National Taiwan University, Taipei, 7Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Medical University Hospital, Taipei, 8Department of Internal Medicine, Taipei Medical University, Taipei, 9Department of Biochemistry, Taipei Medical University, Taipei, 10Institute of Biochemistry and Biotechnology, Chung Shan Medical University, Taichung, 11Neuroscience Research Center, Taipei Medical University Hospital, Taipei, 12Research Center for Biomedical Implants and Microsurgery Devices, Taipei Medical University, Taipei, Taiwan*These authors contributed equally to this workAbstract: Increased expression of cellular membrane bound glucose-regulated protein 78 (GRP78 is considered to be one of the biomarkers for gastric cancers. Therefore, peptides or molecules with specific recognition to GRP78 can act as a guiding probe to direct conjugated imaging agents to localized cancers. Based on this rationale, GRP78-guided polymeric micelles were designed and manufactured for nuclear imaging detection of tumors. Thiolated GRP78 binding peptide (GRP78BP was first labeled with maleimide-terminated poly(ethylene glycol–poly(ε-caprolactone and then mixed with diethylenetriaminepentaacetic acid (DTPA-linked poly(ethylene glycol–poly(ε-caprolactone to form DTPA/GRP78BP-conjugated micelles. The coupling efficiency of micelles with

Leadership in a (permanent) crisis.

Science.gov (United States)

Heifetz, Ronald; Grashow, Alexander; Linsky, Marty

2009-01-01

The current economic crisis is not just another rough spell. Today's mix of urgency, high stakes, and uncertainty will continue even after the recession ends. The immediate crisis--which we will get through with policy makers' expert technical adjustments--sets the stage for a sustained, or even permanent, crisis, a relentless series of challenges no one has encountered before. Instead of hunkering down and relying on their familiar expertise to deal with the sustained crisis, people in positions of authority--whether they are CEOs or managers heading up a company initiative--must practice what the authors call adaptive leadership. They must, of course, tackle the underlying causes of the crisis, but they must also simultaneously make the changes that will allow their organizations to thrive in turbulent environments. Adaptive leadership is an improvisational and experimental art, requiring some new practices. Like Julie Gilbert, who overcame internal resistance to reorient Best Buy toward female purchasers, adaptive leaders get things done to meet today's challenges and then modify those things to thrive in tomorrow's world. They also embrace disequilibrium, using turbulence as an opportunity to build crucial new capacities, as Paul Levy did to rescue Beth Israel Deaconess Medical Center from a profound financial crisis. Finally, adaptive leaders, such as Egon Zehnder, the founder of an executive search firm, draw out the leadership skills that reside deep in the organization, recognizing the interdependence of all employees and mobilizing everyone to generate solutions.

Notas sobre a construção da antropologia no Brasil

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Sílvio Coelho dos Santos

Full Text Available Resumo A antropologia brasileira tem diferentes marcos e, também, diversos heróis fundadores. Destaco a fundação da Universidade de São Paulo, em 1934, por ter possibilitado a contratação, entre outros, dos professores Claude Lévi-Strauss, Radcliffe-Brown, Donald Pierson e Emílio Willems, que foram, junto com Herbert Baldus, responsáveis pela inspiração e formação de profissionais como Darcy Ribeiro, Egon Schaden, Florestan Fernandes e Roberto Cardoso de Oliveira. Fora deste contexto, lembramos Curt Nimuendajú, o maior de nossos etnógrafos, e Gilberto Freyre e Eduardo Galvão, este último o primeiro brasileiro a obter o PhD em Antropologia. A Antropologia Social como entendemos hoje, cresce e se afirma como campo de conhecimento, a partir da Reforma Universitária de 1970, com a generalização dos programas de Pós-Graduação. Roberto Cardoso de Oliveira teve, antes deste momento, a iniciativa de implantar no Museu Nacional (RJ, um extenso Programa de Pós-Graduação em Antropologia Social, cuja primeira experiência ocorreu ainda como especialização, em I960. Na Região Sul, o desenvolvimento da Antropologia, a partir dos anos cinqüenta, teve suas especificidades. Dois médicos e um padre foram os primeiros catedráticos da disciplina.

Photochemistry and photophysics of the amino and imino tautomers of 1-methylcytosine: tautomerisation as a side product of the radiationless decay.

Science.gov (United States)

Li, Quansong; Blancafort, Lluís

2013-08-01

The photochemistry and photophysics of the amino-oxo (AO) and imino-oxo (IO) tautomers of 1-methylcytosine are investigated with ab initio calculations, using the CASPT2//CASSCF approach. Our aim is to rationalize recent experimental results which show that the AO tautomer has an excited state lifetime of about 1 ps, similar to cytosine (J.-W. Ho, H.-C. Yen, W.-K. Chou, C.-N. Weng, L.-H. Cheng, H.-Q. Shi, S.-H. Lai and P.-Y. Cheng, J. Phys. Chem. A, 2011, 115, 8406-8418), and that irradiation with wavelengths shorter than 308 nm induces the AO→IO tautomerization (I. Reva, M. J. Nowak, L. Lapinski and R. Fausto, J. Phys. Chem. B, 2012, 116, 5703-5710). For the canonical AO tautomer we find two analogous decay mechanisms to those described previously for cytosine, involving a conical intersection of ethylenic type and one where the amino group is bent out of plane. Decay through these intersections provides an unreactive return path to the AO ground state species. More importantly, we have identified new decay paths that lead from the two intersections to the trans-IO tautomer, without a barrier. These paths provide the possibility of forming the IO tautomer, presumably in small yields, as a side product of the radiationless decay. Thus, we have established for the first time computationally the mechanism of the UV-induced tautomerization, which is compatible with the well-established decay mechanism for cytosine. For the IO tautomer, we also find a mechanism for the excited state interconversion of the cis and trans forms and for efficient radiationless decay through a conical intersection where the imino group is perpendicular to the ring and bent out of the plane. These results are likely to be valid also for cytosine.

In vivo toxicologic study of larger silica nanoparticles in mice

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Chan WT

2017-04-01

Full Text Available Wai-Tao Chan,1–3 Cheng-Che Liu,4 Jen-Shiu Chiang Chiau,5 Shang-Ting Tsai,6 Chih-Kai Liang,6 Mei-Lien Cheng,5 Hung-Chang Lee,7,8 Chun-Yun Yeung,1,3,9 Shao-Yi Hou2,6 1Department of Pediatric Gastroenterology, Hepatology and Nutrition, MacKay Children’s Hospital, 2Graduate Institute of Engineering Technology, National Taipei University of Technology, 3Mackay Medicine, Nursing, and Management College, 4Institute of Preventive Medicine, National Defense Medical Center, Taipei, 5Department of Medical Research, MacKay Memorial Hospital, Hsinchu, 6Graduate Institute of Biochemical and Biomedical Engineering, National Taipei University of Technology, Taipei, 7Department of Pediatrics, MacKay Memorial Hospital, Hsinchu, 8Department of Pediatrics, Taipei Medical University, Taipei, 9Department of Medicine, Mackay Medical College, New Taipei, Taiwan, Republic of China Abstract: Silica nanoparticles (SiNPs are being studied and used for medical purposes. As nanotechnology grows rapidly, its biosafety and toxicity have frequently raised concerns. However, diverse results have been reported about the safety of SiNPs; several studies reported that smaller particles might exhibit toxic effects to some cell lines, and larger particles of 100 nm were reported to be genotoxic to the cocultured cells. Here, we investigated the in vivo toxicity of SiNPs of 150 nm in various dosages via intravenous administration in mice. The mice were observed for 14 days before blood examination and histopathological assay. All the mice survived and behaved normally after the administration of nanoparticles. No significant weight change was noted. Blood examinations showed no definite systemic dysfunction of organ systems. Histopathological studies of vital organs confirmed no SiNP-related adverse effects. We concluded that 150 nm SiNPs were biocompatible and safe for in vivo use in mice. Keywords: in vivo, mice, silica nanoparticle, nanotoxicity

Development and evaluation of pH-responsive single-walled carbon nanotube-doxorubicin complexes in cancer cells

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Gu YJ

2011-11-01

Full Text Available Yan-Juan Gu1,2,*, Jinping Cheng2,*, Jiefu Jin3, Shuk Han Cheng2, Wing-Tak Wong11Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, 2Department of Biology and Chemistry, The City University of Hong Kong, 3Department of Chemistry, The University of Hong Kong, Hong Kong, China*These authors contributed equally to this workAbstract: Single-walled carbon nanotubes (SWNTs have been identified as an efficient drug carrier. Here a controlled drug-delivery system based on SWNTs coated with doxorubicin (DOX through hydrazone bonds was developed, because the hydrazone bond is more sensitive to tumor microenvironments than other covalent linkers. The SWNTs were firstly stabilized with polyethylene glycol (H2N-PEG-NH2. Hydrazinobenzoic acid (HBA was then covalently attached on SWNTs via carbodiimide-activated coupling reaction to form hydrazine-modified SWNTs. The anticancer drug DOX was conjugated to the HBA segments of SWNT using hydrazine as the linker. The resulting hydrazone bonds formed between the DOX molecules and the HBA segments of SWNTs are acid cleavable, thereby providing a strong pH-responsive drug release, which may facilitate effective DOX release near the acidic tumor microenvironment and thus reduce its overall systemic toxicity. The DOX-loaded SWNTs were efficiently taken up by HepG2 tumor cells, and DOX was released intracellularly, as revealed by MTT assay and confocal microscope observations. Compared with SWNT-DOX conjugate formed by supramolecular interaction, the SWNT-HBA-DOX featured high weight loading and prolonged release of DOX, and thus improved its cytotoxicity against cancer cells. This study suggests that while SWNTs have great potential as a drug carrier, the efficient formulation strategy requires further study.Keywords: carbon nanotubes, drug delivery, controlled release, SWNTs

Historical droughts in northern Vietnam captured by variability in speleothem δ18O

Science.gov (United States)

Hardt, B. F.; McGee, D.; Burns, S. J.; Hieu, N.; Hieu, D. T.

2015-12-01

Speleothem records overlapping with the historical period offer valuable comparisons of documentary evidence with speleothem proxy data. These records provide opportunities to 'ground-truth' the paleo-record, fill in gaps in the historical record, and more confidently extent the paleo-record into deeper time. Here we present isotopic results from a stalagmite collected in northern Vietnam spanning 1200 to 1950 CE, a period with a rich historical record in Vietnam. This sample adds significantly to the relatively sparse paleoclimate record from Southeast Asia. The record includes several multi-decadal positive excursions of ≥1 per mille in calcite δ18O. A preliminary age model, based on six U/Th ages, suggests possible correspondence to noted droughts from the historical record, including the Angkor Droughts, the Ming Dynasty Drought, the Strange Parallels Drought, and the Victorian Holocaust Drought. As modeling studies indicate a strong correlation between rainfall δ18O and both the intensity of summer monsoon winds and summer rainfall over northern Vietnam (e.g., Liu et al., 2014), these excursions are consistent with a decrease in regional precipitation. The Vietnam record shows an overall negative trend during the Little Ice Age. The study site is located well south of the westerly wind belt, ruling out a shift between monsoonal and mid-latitude circulation systems as a likely explanation for the northern Vietnam record. We explore the correspondence between our record and other proxy data from Southeast Asia and suggest possible implications of the differences between Vietnamese and Chinese speleothem records during the Little Ice Age. References cited: Liu Z., Wen X., Brady E. C., Otto-Bliesner B., Yu G., Lu H., Cheng H., Wang Y., Zheng W., Ding Y., Edwards R. L., Cheng J., Liu W. and Yang H. (2014) Chinese cave records and the East Asia Summer Monsoon. Quaternary Science Reviews 83, 115-128.

Development of Taiwan’s strategies for regulating nanotechnology-based pharmaceuticals harmonized with international considerations

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Guo JW

2014-10-01

Full Text Available Jiun-Wen Guo,1 Yu-Hsuan Lee,2 Hsiau-Wen Huang,3 Mei-Chyun Tzou,3 Ying-Jan Wang,2 Jui-Chen Tsai1,4 1Institute of Clinical Pharmacy and Pharmaceutical Sciences, College of Medicine, National Chung Kung University, Tainan, Taiwan; 2Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan; 3Food and Drug Administration, Ministry of Health and Welfare, Taiwan; 4Center for Pharmaceutical Regulatory Science, National Cheng Kung University, Tainan, Taiwan Abstract: Nanotechnology offers potential in pharmaceuticals and biomedical developments for improving drug delivery systems, medical imaging, diagnosis, cancer therapy, and regenerative medicine. Although there is no international regulation or legislation specifically for nanomedicine, it is agreed worldwide that considerably more attention should be paid to the quality, safety, and efficacy of nanotechnology-based drugs. The US Food and Drug Administration and the European Medicines Agency have provided several draft regulatory guidance and reflection papers to assist the development of nanomedicines. To cope with the impact of nanotechnology and to foster its pharmaceutical applications and development in Taiwan, this article reviews the trends of regulating nanotechnology-based pharmaceuticals in the international community and proposes strategies for Taiwan’s regulation harmonized with international considerations. The draft regulatory measures include a chemistry, manufacturing, and controls (CMC review checklist and guidance for CMC review of liposomal products. These have been submitted for discussion among an expert committee, with membership comprised of multidisciplinary academia, research institutions, the pharmaceutical industry, and regulators, and are currently approaching final consensus. Once a consensus is reached, these mechanisms will be recommended to the Taiwan Food and Drug Administration for jurisdiction and may

On the nullity number of graphs

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Mustapha Aouchiche

2017-10-01

Full Text Available The paper discusses bounds on the nullity number of graphs. It is proved in [B. Cheng and B. Liu, On the nullity of graphs. Electron. J. Linear Algebra 16 (2007 60--67] that $\\eta \\le n - D$, where $\\eta$, n and D denote the nullity number, the order and the diameter of a connected graph, respectively. We first give a necessary condition on the extremal graphs corresponding to that bound, and then we strengthen the bound itself using the maximum clique number. In addition, we prove bounds on the nullity using the number of pendant neighbors in a graph. One of those bounds is an improvement of a known bound involving the domination number.

Elastic scattering of low energy γ-rays

International Nuclear Information System (INIS)

Whittingham, I.B.

1978-05-01

Theoretical cross sections for the elastic scattering of 245, 334, 444, 779, 1086, 1112 and 1408 keV γ-rays by Pb are obtained for scattering angles up to 150 degrees. Three sets of Rayleigh scattering amplitudes have been computed using (1) the calculations of Johnson and Cheng, (2) the K shell calculations of Brown and co-workers supplemented by form factors amplitudes for higher shells, and (3) form factor amplitudes for all shells. Nuclear Thomson amplitudes have been included for all energies and, for 1408 keV, Delbruck scattering based upon the calculations of Papatzacos and Mork has been included. Nuclear resonance scattering is show to be negligble for all energies

Supporting learning and promoting conceptual change with box and AVOW diagrams. Part 1: Representational design and instructional approaches

Science.gov (United States)

Cheng, Peter C.-H.; Shipstone, David M.

2003-02-01

A new approach to the teaching of electricity is described that uses box and AVOW diagrams, novel representations of the properties of the electric circuit which portray current, voltage, resistance and power. The diagrams have been developed as aids to learning, understanding and problem solving. They also have the potential to promote conceptual change by challenging a number of commonly held misconceptions. The diagrams have been incorporated into A-level teaching materials on d.c. circuit theory and the rationale for this approach is contrasted with a number of strategies that have previously been reported. Part 2 of this paper (Cheng and Shipstone, International Journal of Science Education, in press) will present the results of preliminary school-based trials.

Multifractality and herding behavior in the Japanese stock market

International Nuclear Information System (INIS)

Cajueiro, Daniel O.; Tabak, Benjamin M.

2009-01-01

In this paper we present evidence of multifractality and herding behavior for a large set of Japanese stocks traded in the Tokyo Stock Exchange. We find evidence that herding behavior occurs in periods of extreme market movements. Therefore, based on the intuition behind the tests to detect herding phenomenon developed, for instance, in Christie and Huang [Christie W, Huang R. Following the pied pier: do individual returns herd around the market? Financ Analysts J 1995;51:31-7] and Chang et al. [Chang EC, Cheng JW, Khorana A. Examination of herd behavior in equity markets: an international perspective. J Bank Finance 2000;24:1651-99], we suggest that herding behavior may be one of the causes of multifractality.

Association of sustained virologic response with reduced progression to liver cirrhosis in elderly patients with chronic hepatitis C

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Tseng CW

2016-03-01

Full Text Available Chih-Wei Tseng,1,2 Ting-Tsung Chang,3,4 Shinn-Jia Tzeng,5 Yu-Hsi Hsieh,1,2 Tsung-Hsing Hung,1,2 Hsiang-Ting Huang,6 Shu-Fen Wu,7 Kuo-Chih Tseng1,2 1Department of Internal Medicine, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chia-Yi, 2School of Medicine, Tzuchi University, Hualien, 3Department of Internal Medicine, National Cheng Kung University Medical College and Hospital, 4Infectious Disease and Signaling Research Center, National Cheng Kung University, Tainan, 5Department of Agronomy, National Chiayi University, 6Department of Nursing, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, 7Institute of Molecular Biology, National Chung Cheng University, Chia-Yi, Taiwan Objective: We studied the effect of sustained virologic response (SVR after treatment with pegylated-interferon (PEG-IFN plus ribavirin on the development of liver cirrhosis in elderly patients with chronic hepatitis C (CHC. Patients and methods: This retrospective study enrolled 145 elderly CHC patients (aged ≥65 years who were treatment-naïve and were treated with PEG-IFN plus ribavirin for 6 months between January 2005 and December 2011. Abdominal sonography was performed and liver biochemistry was studied at baseline, at the end of treatment, and every 3–6 months thereafter. The development of liver cirrhosis and related complications was evaluated at the follow-ups. The aspartate aminotransferase-to-platelet ratio index was used as a noninvasive maker for fibrosis. Results: The mean patient age was 69.1±3.3 years, and the average follow-up time was 5.5 years (standard deviation: 2.5 years, range: 1.1–12.3 years. Ninety-five patients (65.5% achieved SVR, and 26 (17.9% discontinued treatment. Twenty-seven patients (18.6% developed liver cirrhosis after treatment. Patients without SVR had significantly greater risk of liver cirrhosis than those with SVR (hazard ratio [HR]: 3.39, 95% confidence interval [CI]: 1.312–8.761, P=0.012. The

Orthorhombic polymorph of 4-[(1H-benzimidazol-1-ylmethyl]benzoic acid

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Hai-Wei Kuai

2011-11-01

Full Text Available We reported recently the first polymorph of the title compound [Kuai & Cheng (2011a. Acta Cryst., E67, o2787]. A second polymorph of the title compound, C15H12N2O2, was unexpectedly obtained by the hydrothermal reaction of the title compound with manganese chloride in the presence of potassium hydroxide at 413 K. The benzimidazole ring system is almost planar, with a maximum deviation from the mean plane of 0.015 (2 Å. The benzimidazole and benzene rings are inclined at a dihedral angle of 79.00 (1°. In the crystal, adjacent molecules are connected through O—H...N hydrogen bonds into a one-dimensional chain along the [001] direction.

Mesoscopic pairing without superconductivity

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Hofmann, Johannes

2017-12-01

We discuss pairing signatures in mesoscopic nanowires with a variable attractive pairing interaction. Depending on the wire length, density, and interaction strength, these systems realize a simultaneous bulk-to-mesoscopic and BCS-BEC crossover, which we describe in terms of the parity parameter that quantifies the odd-even energy difference and generalizes the bulk Cooper pair binding energy to mesoscopic systems. We show that the parity parameter can be extracted from recent measurements of conductance oscillations in SrTiO3 nanowires by Cheng et al. [Nature (London) 521, 196 (2015), 10.1038/nature14398], where it marks the critical magnetic field that separates pair and single-particle currents. Our results place the experiment in the fluctuation-dominated mesoscopic regime on the BCS side of the crossover.

An ab initio study of potential energy surfaces of CH 3COCN dissociation on the low-lying states

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Ding, Wan-Jian; Fang, Wei-Hai; Liu, Ruo-Zhuang

2002-01-01

The C-CH 3 and C-CN bond dissociations of CH 3COCN on S 1 and T 1 surfaces are studied at the CAS(8,7)/cc-pVDZ level. The results show that the intersystem crossing from S 1 to T 1 is a favorable pathway of S 1 deactivation. Once on the T 1 surface, the system can dissociate adiabatically to CH3 ( X˜)+ OCCN ( X˜) or CN ( X˜)+ CH3CO ( X˜) , but the former has some preference over the latter. This mechanism is consistent with Cheng's presumption deduced from the experimental facts and theoretical considerations. A comparison with other asymmetrically substituted carbonyl compounds suggests that the selectivity of the α-bond cleavage is mainly dependent on the mechanism of dissociation.

Analysis of the pion-kaon sigma term and related topics

International Nuclear Information System (INIS)

Frink, M.; Kubis, B.; Meissner, U.G.

2002-01-01

We calculate the one-loop contributions to the difference Δ πK between the isoscalar on-shell pion-kaon scattering amplitude at the Cheng-Dashen point and the scalar form factor Γ K (2M 2 π ) in the framework of three flavor chiral perturbation theory. These corrections turn out to be small. This is further sharpened by treating the kaons as heavy fields (two flavor chiral perturbation theory). We also analyze the two-loop corrections to the kaon scalar form factor based on a dispersive technique. We find that these corrections are smaller than in the comparable case of the scalar form factor of the pion. This is related to the weaker final state interactions in the pion-kaon channel. (orig.)

Analysis of the pion-kaon sigma term and related topics

Energy Technology Data Exchange (ETDEWEB)

Frink, M.; Kubis, B.; Meissner, U.G. [Forschungszentrum Juelich, Institut fuer Kernphysik (Theorie), Juelich (Germany)

2002-09-01

We calculate the one-loop contributions to the difference {delta}{sub {pi}}{sub K} between the isoscalar on-shell pion-kaon scattering amplitude at the Cheng-Dashen point and the scalar form factor {gamma}{sub K} (2M{sup 2}{sub {pi}}) in the framework of three flavor chiral perturbation theory. These corrections turn out to be small. This is further sharpened by treating the kaons as heavy fields (two flavor chiral perturbation theory). We also analyze the two-loop corrections to the kaon scalar form factor based on a dispersive technique. We find that these corrections are smaller than in the comparable case of the scalar form factor of the pion. This is related to the weaker final state interactions in the pion-kaon channel. (orig.)

History of Neurology in China

Institute of Scientific and Technical Information of China (English)

Wang Xinde

2000-01-01

@@In 1921, the first independent department of neurology was established in Beijing. Before 1949, all over China only 12 professional doctors lectured neurology in medical colleges. Only 30 medically trained personnel were engaged in the neurological departments. The neurological departments contained roughly 200 beds. The thesis on stroke was written by Zhang Shanlei and published in 1922. Author discussed the cerebral stroke on basis of Chinese traditional medicine and European medicine. The first Textbook of Neurology in China was written by Professor Cheng Yu-lin and was published in 1939. In 1952, the Chinese Society of Neurology and Psychiatry of Chinese Medical Association was established. In 1955, the first issue of the Chinese Journal of Neurology and Psychiatry was published.

The Complexities of Implementing Cluster Supply Chain - Case Study of JCH

Science.gov (United States)

Xue, Xiao; Zhang, Jibiao; Wang, Yang

As a new type of management pattern, "cluster supply chain" (CSC) can help SMEs to face the global challenges through all kinds of collaboration. However, a major challenge in implementing CSC is the gap between theory and practice in the field. In an effort to provide a better understanding of this emerging phenomenon, this paper presents the implementation process of CSC in the context of JingCheng Mechanical & Electrical Holding co., ltd.(JCH) as a case study. The cast study of JCH suggests that the key problems in the practice of cluster supply chain: How do small firms use cluster supply chain? Only after we clarify the problem, the actual construction and operation of cluster supply chain does show successful results as it should be.

How-to establish PCST. Two handbooks on science communication

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Alessandro Delfanti

2008-12-01

Full Text Available In 2008 two collections were published: the Handbook of Public Communication of Science and Technology, edited by Massimiano Bucchi and Brian Trench, and Communicating Science in Social Contexts: New models, new practices, edited by Donghong Cheng and five other scholars from China, Canada, Belgium and Australia. These books try to define and draw the boundaries of science communication’s field from both a theoretical and empirical point of view. But do we need to establish it as a distinct research field? For a number of decades, a growing community of scholars and communicators is trying to reply positively to this question, but the need to look outside the disciplinary boundaries, to other academic fields, is still vital.

Important contributions of M.C. Wang and C.S. Wang Chang to non-equilibrium statistical physics

International Nuclear Information System (INIS)

Liu Jixing

2004-01-01

In the middle of the 20th century two Chinese women physicists, Ming-Chen Wang and Cheng-Shu Wang Chang made great contributions to statistical physics. The famous review article 'On the theory of the Brownian motion II' by Ming-Chen Wang and G.E. Uhlenbeck published in Rev. of Mod. Phys. in 1945 provided a complete scientific classification of stochastic processes which is still adopted by the scientific community as the standard classification. The Wang-Chang-Uhlenbeck (WCU) equation proposed jointly by C.S. Wang-Chang and Uhlenbeck became the fundamental kinetic equation for the treatment of transport properties of multi-atomic gases with internal degrees of freedom in the physics literature. These important scientific contributions are analyzed and reviewed

Stressors of dual-qualification nursing teachers in the ChengDu-ChongQing economic zone of China--a qualitative study.

Science.gov (United States)

Wu, Youfeng; Liu, Hui; He, Hongyan

2013-12-01

Nursing and teaching are considered risk professions with high levels of stress and burnout. Dual-qualification nursing teachers (DQNT) are nurses who both teach and practise. These nurses face additional stress. This study explored the stressors of DQNT in the Chengdu-Chongqing Economic Zone of China. This qualitative study used in-depth, open-ended interviews. The interview responses were analysed using a grounded theory approach. The participants in this study included 21 DQNT from 5 teaching hospitals in the Chengdu-Chongqing Economic Zone of China. The results indicated that heavy workload, personal safety, inadequate pay, role overload, and poor working environment are stressors of DQNT. Furthermore, Chinese DQNT face violence from patients and students. The study provides a theoretical basis to help DQNT to cope with stress. Copyright © 2013 Elsevier Ltd. All rights reserved.

Structural characterisation of a water-soluble polysaccharide from tissue-cultured Dendrobium huoshanense C.Z. Tang et S.J. Cheng.

Science.gov (United States)

Si, Hua-Yang; Chen, Nai-Fu; Chen, Nai-Dong; Huang, Cheng; Li, Jun; Wang, Hui

2018-02-01

A water-soluble polysaccharide TC-DHPA4 with a molecular weight of 8.0 × 10 5  Da was isolated from tissue-cultured Dendrobium huoshanense by anion exchange and gel permeation chromatography. Monosaccharide analysis revealed that the homogeneous polysaccharide was made up of rhamnose, arabinose, mannose, glucose, galactose and glucuronic acid with a molar ratio of 1.28:1:1.67:4.71:10.43:1.42. The sugar residue sequence analysis based on the GC-MS files and NMR spectra indicated that the backbone of TC-DHPA4 consisted of the repeated units:→6)-β-Galp-(1→6)-β-Galp-(1→4)-β-GlcpA-(1→6)-β-Glcp-(1→6)-β-Glcp-(→. The sugar residue sequences β-Glcp-(1→)-α-Rhap-(1→3)-β-Galp-(1→, β-Glcp-(1→4)-α-Rhap-(1→3)-β-Galp-(1→, β-Galp-(1→6)-β-Manp-(1→3)-β-Galp-(1→, and α-l-Araf-(1→2)-β-Manp-(1→3)-β-Galp-(1→ were identified as the branches attached to the C-3 position of (1→6)-linked galactose in the backbone.

Towards large volume big divisor D3/D7 “μ-split supersymmetry” and Ricci-flat Swiss-cheese metrics, and dimension-six neutrino mass operators

International Nuclear Information System (INIS)

Dhuria, Mansi; Misra, Aalok

2012-01-01

We show that it is possible to realize a “μ-split SUSY” scenario (Cheng and Cheng, 2005) in the context of large volume limit of type IIB compactifications on Swiss-cheese Calabi-Yau orientifolds in the presence of a mobile space-time filling D3-brane and a (stack of) D7-brane(s) wrapping the “big” divisor. For this, we investigate the possibility of getting one Higgs to be light while other to be heavy in addition to a heavy higgsino mass parameter. Further, we examine the existence of long lived gluino that manifests one of the major consequences of μ-split SUSY scenario, by computing its decay width as well as lifetime corresponding to the three-body decays of the gluino into either a quark, a squark and a neutralino or a quark, squark and goldstino, as well as two-body decays of the gluino into either a neutralino and a gluon or a goldstino and a gluon. Guided by the geometric Kähler potential for Σ B obtained in Misra and Shukla (2010) based on GLSM techniques, and the Donaldson's algorithm (Barun et al., 2008) for obtaining numerically a Ricci-flat metric, we give details of our calculation in Misra and Shukla (2011) pertaining to our proposed metric for the full Swiss-cheese Calabi-Yau (the geometric Kähler potential being needed to be included in the full moduli space Kähler potential in the presence of the mobile space-time filling D3-brane), but for simplicity of calculation, close to the big divisor, which is Ricci-flat in the large volume limit. Also, as an application of the one-loop RG flow solution for the higgsino mass parameter, we show that the contribution to the neutrino masses at the EW scale from dimension-six operators arising from the Kähler potential, is suppressed relative to the Weinberg-type dimension-five operators.

Towards large volume big divisor D3/D7 " μ-split supersymmetry" and Ricci-flat Swiss-cheese metrics, and dimension-six neutrino mass operators

Science.gov (United States)

Dhuria, Mansi; Misra, Aalok

2012-02-01

We show that it is possible to realize a " μ-split SUSY" scenario (Cheng and Cheng, 2005) [1] in the context of large volume limit of type IIB compactifications on Swiss-cheese Calabi-Yau orientifolds in the presence of a mobile space-time filling D3-brane and a (stack of) D7-brane(s) wrapping the "big" divisor. For this, we investigate the possibility of getting one Higgs to be light while other to be heavy in addition to a heavy higgsino mass parameter. Further, we examine the existence of long lived gluino that manifests one of the major consequences of μ-split SUSY scenario, by computing its decay width as well as lifetime corresponding to the three-body decays of the gluino into either a quark, a squark and a neutralino or a quark, squark and goldstino, as well as two-body decays of the gluino into either a neutralino and a gluon or a goldstino and a gluon. Guided by the geometric Kähler potential for Σ obtained in Misra and Shukla (2010) [2] based on GLSM techniques, and the Donaldson's algorithm (Barun et al., 2008) [3] for obtaining numerically a Ricci-flat metric, we give details of our calculation in Misra and Shukla (2011) [4] pertaining to our proposed metric for the full Swiss-cheese Calabi-Yau (the geometric Kähler potential being needed to be included in the full moduli space Kähler potential in the presence of the mobile space-time filling D3-brane), but for simplicity of calculation, close to the big divisor, which is Ricci-flat in the large volume limit. Also, as an application of the one-loop RG flow solution for the higgsino mass parameter, we show that the contribution to the neutrino masses at the EW scale from dimension-six operators arising from the Kähler potential, is suppressed relative to the Weinberg-type dimension-five operators.

Anxiety and mood disorder in young males with mitral valve prolapse

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For-Wey Lung

2008-10-01

Full Text Available For-Wey Lung1–4, Chih-Tao Cheng5, Wei-To Chang6, Bih-Ching Shu71Department of Psychiatry, Kaohsiung Armed Forces General Hospital, Kaohsiung, Taiwan; 2Graduate Institute of Behavioral Sciences, Kaohsiung Medical Center, Taiwan; 3Department of Psychiatry, National Defense Medical Center, Taipei, Taiwan; 4Calo Psychiatric Center, Pingtung County, Taiwan; 5School of public Health, University of California, Berkeley, CA, USA; 6Liu Chia-Hsiu Hospital, Kaohsiung County, Taiwan; 7Institute of Allied Health Sciences and Department of Nursing, National Cheng Kung University, Tainan, TaiwanObjective: This study explored the prevalence of panic disorder and other psychiatric disorders in young Han Chinese males with mitral valve prolapse (MVP. With the factors of age, sex, and ethnicity controlled, the specific role of MVP in panic disorder was analyzed. Methods: Subjects with chest pain aged between 18 and 25 years were assessed with the echocardiograph for MVP and the Chinese version of the Mini-International Neuropsychiatric Interview for panic disorder (n = 39.Results: Of the 39 participants, 35.9% met the diagnosis of anxiety disorder, 46.2% met at least one criterion of anxiety disorder, and 23.1% met the diagnostic criteria of major depressive disorder. There was no statistically significant difference in the prevalence of panic disorder between one of the (8.3% MVP patients, and two (7.4% control participants.Conclusions: There is a high prevalence of psychiatric disorder, including anxiety disorder and major depressive disorder, in those who report pain symptoms, so that diagnosis and treatment of these patients is of great importance. In addition, individuals with MVP did not have an increased risk for panic disorder. Whether MVP may be a modifier or mediating factor for panic disorder needs to be further assessed in a larger scale study.Keywords: mitral valve prolapse, panic disorder, Han Chinese males, major depressive disorder

Midazolam induces apoptosis in MA-10 mouse Leydig tumor cells through caspase activation and the involvement of MAPK signaling pathway

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So EC

2014-02-01

Full Text Available Edmund Cheung So,1,2 Yu-Xuan Lin,3 Chi Hao Tseng,1 Bo-Syong Pan,3 Ka-Shun Cheng,2 Kar-Lok Wong,2 Lyh-Jyh Hao,4 Yang-Kao Wang,5 Bu-Miin Huang2 1Department of Anesthesia, Tainan Municipal An Nan Hospital, China Medical University, Tainan, Taiwan; 2Department of Anesthesia, China Medical University, Taichung, Taiwan; 3Department of Cell Biology and Anatomy, National Cheng Kung University, Tainan, Taiwan; 4Department of Internal Medicine, Division of Endocrinology and Metabolism, Kaohsiung Veteran General Hospital Tainan Branch Tainan, Taiwan; 5Graduate Institute of Biomedical Materials and Tissue Engineering, Taipei Medical University, Taipei, Taiwan Purpose: The present study aims to investigate how midazolam, a sedative drug for clinical use with cytotoxicity on neuronal and peripheral tissues, induced apoptosis in MA-10 mouse Leydig tumor cells. Methods: The apoptotic effect and underlying mechanism of midazolam to MA-10 cells were investigated by flow cytometry assay and Western blotting methods. Results: Data showed that midazolam induced the accumulation of the MA-10 cell population in the sub-G1 phase and a reduction in the G2/M phase in a time- and dose-dependent manner, suggesting an apoptotic phenomenon. Midazolam could also induce the activation of caspase-8, -9, and -3 and poly (ADP-ribose polymerase proteins. There were no changes in the levels of Bax and cytochrome-c, whereas Bid was significantly decreased after midazolam treatment. Moreover, midazolam decreased both pAkt and Akt expression. In addition, midazolam stimulated the phosphorylation of p38 and c-Jun NH2-terminal kinase but not extracellular signal-regulated kinase. Conclusion: Midazolam could induce MA-10 cell apoptosis through the activation of caspase cascade, the inhibition of pAkt pathway, and the induction of p38 and c-Jun NH2-terminal kinase pathways. Keywords: midazolam, apoptosis, MA-10 cell, caspase, Akt, MAPKs

The prevalence and prognostic significance of KRAS mutation subtypes in lung adenocarcinomas from Chinese populations

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Zheng DF

2016-02-01

Full Text Available Difan Zheng,1,2,* Rui Wang,1,2,* Yang Zhang,1,2 Yunjian Pan,1,2 Xinghua Cheng,3 Chao Cheng,1,2 Shanbo Zheng,1,2 Hang Li,1,2 Ranxia Gong,1,2 Yuan Li,2,4 Xuxia Shen,2,4 Yihua Sun,1,2 Haiquan Chen1–3,51Department of Thoracic Surgery, Fudan University Shanghai Cancer Center, 2Department of Oncology, Shanghai Medical College, Fudan University, 3Shanghai Chest Hospital, Shanghai Jiao Tong University, 4Department of Pathology, Fudan University Shanghai Cancer Center, 5Institutes of Biomedical Sciences, Fudan University, Shanghai, People’s Republic of China*These authors contributed equally to this workBackground: We performed this retrospective study to identify the prevalence of KRAS mutation in Chinese populations and make a comprehensive investigation of the clinicopathological features of KRAS mutation in these patients.Patients and methods: Patients from 2007 to 2013 diagnosed with primary lung adenocarcinoma who received a radical resection were examined for KRAS, EGFR, HER2, BRAF mutations, and ALK, RET, and ROS1 fusions. Clinicopathological features, including sex, age, tumor–lymph node–metastasis stage, tumor differentiation, smoking status, histological subtypes, and survival information were analyzed.Result: KRAS mutation was detected in 113 of 1,368 patients. Nine different subtypes of KRAS mutation were identified in codon 12, codon 13, and codon 61. KRAS mutation was more frequently found in male patients and former/current smoker patients. Tumors with KRAS mutation had poorer differentiation. Invasive mucinous adenocarcinoma predominant and solid predominant subtypes were more frequent in KRAS mutant patients. No statistical significance was found in relapse-free survival or overall survival between patients with KRAS mutation and patients with other mutations.Conclusion: In Chinese populations, we identified KRAS mutation in 8.3% (113/1,368 of the patients with lung adenocarcinoma. KRAS mutation defines a molecular subset of

Spatial variability of NDVI at different seasons in the Community of Madrid (Spain)

Science.gov (United States)

Sotoca, Juan J. Martin; Saa-Requejo, Antonio; Borondo, Javier; Tarquis, Ana M.

2015-04-01

Agricultural drought quantification is one of the most important tasks in the characterization process of this natural hazard and its implications in crop insurance. Recently, several vegetation indexes based on remote-sensing data (VI) has been applied to quantify it (Dalezios et al, 2012). VIs are obtained combining several frequency bands that represent the relationship between photosynthesis and absorbed/reflected radiation. The most widely used VI is the Normalized Difference Vegetation Index (NDVI). It is based on the principle that healthy vegetation mainly absorbs visible light and reflects the near-infrared frequency band. Drought can be highly localized, and several authors have recognized the critical role of soil moisture and its spatial variability in agricultural losses (Anderson et al., 2011). Therefore, it is important to delimit locations within a homogeneous area that will share main NDVI statistics and in which the same threshold value can be applied to define drought event. In order to do so, we have applied for the first time in this context the method of singularity maps (Cheng and Agterberg, 1996) commonly used in localization of mineral deposits. The NDVI singularity maps calculated in each season through 2011/2012 are showed and discussed (Martín-Sotoca, 2014). References Anderson, M:C:, C. R. Hain, B. Wardlow, J. R. Mecikalski and W. P. Kustas (2011) Evaluation of drought indices based on thermal remote sensing of evapotranspiration over the continental United States. J. Climate, 24, 2025-2044. Dalezios, N.R., A. Blanta, N.V. Spyropoulos and A.M. Tarquis (2012) Risk identification of agricultural drought for sustainable Agroecosystems. Nat. Hazards Earth Syst. Sci., 14, 2435-2448. Cheng, Q. and F.P. Agterberg (1996) Multifractal modeling and spatial statistics. Math. Geol., 28, 1-16. Martín-Sotoca, J.J. (2014) Estructura Espacial de la Sequía en Pastos y sus Aplicaciones en el Seguro Agrario. Master Thesis, UPM (In Spanish

Comment on ''Generation of Electromagnetic Pulses from Plasma Channels Induced by Femtosecond Light Strings''

International Nuclear Information System (INIS)

Shvets, Gennady; Kaganovich, Igor; Startsev, Edward

2002-01-01

In a recent Letter, Cheng et al. calculated/predicted several new effects: that (a) fraction of the short laser pulse momentum can be imparted to plasma electrons via collisional damping of the laser, thereby exciting a long-lived (longer than an oscillation period) plasma wave, which (b) gives rise to a spatially uniform dipole moment of a plasma, which (c) emits far-field narrow-band radiation at the plasma frequency omega subscript ''p'' over the recombination time of the plasma. We claim that the calculation of the effect (a) is in error and the predicted effects (b,c) do not occur as described. In fact, predicted narrow-band emission at omega subscript ''p'' would not occur even if the momentum transfer and the dipole excitation were calculated correctly

Nonlinear data assimilation

CERN Document Server

Van Leeuwen, Peter Jan; Reich, Sebastian

2015-01-01

This book contains two review articles on nonlinear data assimilation that deal with closely related topics but were written and can be read independently. Both contributions focus on so-called particle filters. The first contribution by Jan van Leeuwen focuses on the potential of proposal densities. It discusses the issues with present-day particle filters and explorers new ideas for proposal densities to solve them, converging to particle filters that work well in systems of any dimension, closing the contribution with a high-dimensional example. The second contribution by Cheng and Reich discusses a unified framework for ensemble-transform particle filters. This allows one to bridge successful ensemble Kalman filters with fully nonlinear particle filters, and allows a proper introduction of localization in particle filters, which has been lacking up to now.

Ion beam mixing in Ag-Pd alloys

International Nuclear Information System (INIS)

Klatt, J.L.; Averback, R.S.; Peak, D.

1989-01-01

Ion beam mixing during 750 keV Kr + irradiation at 80 K was measured on a series of Ag-Pd alloys using Au marker atoms. The mixing in pure Ag was the greatest and it decreased monotonically with increasing Pd content, being a factor of 10 higher in pure Ag than in pure Pd. This large difference in mixing cannot be explained by the difference in cohesion energy between Ag and Pd in the thermodynamic model of ion beam mixing proposed by Johnson et al. [W. L. Johnson, Y. T. Cheng, M. Van Rossum, and M-A. Nicolet, Nucl. Instrum. Methods B 7/8, 657 (1985)]. An alternative model based on local melting in the cascade is shown to account for the ion beam mixing results in Ag and Pd

International Conference on Advances in Information and Communication Technology

CERN Document Server

Nguyen, Thanh-Thuy; Vu, Duc-Thai; Phung, Trung-Nghia; Huynh, Van-Nam

2017-01-01

This book features papers presented at the International Conference on Advances in Information and Communication Technology (ICTA 2016), which was held in Thai Nguyen city, Vietnam, from December 1 to 13, 2016. The conference was jointly organized by Thai Nguyen University of Information and Communication Technology (ICTU), the Institute of Information Technology – Vietnam Academy of Science and Technology (IoIT), Feng Chia University, Taiwan (FCU), the Japan Advanced Institute of Science and Technology (JAIST) and the National Chung Cheng University, Taiwan (CCU) with the aim of bringing together researchers, academics, practitioners and students to not only share research results and practical applications but also to foster collaboration in information and communication technology research and education. The book includes the 66 best peer-reviewed papers, selected from the 150 submissions received.

Estimates of the pion-nucleon sigma term using dispersion relations and taking into account the relation between chiral and scale invariance breaking

International Nuclear Information System (INIS)

Efrosinin, V.P.; Zaikin, D.A.

1983-01-01

We study the possible reasons for the disagreement between the estimates of the pion-nucleon sigma term obtained by the method of dispersion relations with extrapolation to the Cheng-Dashen point and by other methods which do not involve this extrapolation. One reason for the disagreement may be the nonanalyticity of the πN amplitude in the variable t for ν = 0. We propose a method for estimating the sigma term using the threshold data for the πN amplitude, in which the effect of this nonanalyticity is minimized. We discuss the relation between scale invariance violation and chiral symmetry breaking and give the corresponding estimate of the sigma term. The two estimates are similar (42 and 34 MeV) and are in agreement when the uncertainties of the two methods are taken into consideration

National antimicrobial stewardship and fluoroquinolone-resistant Clostridium difficile in China

Directory of Open Access Journals (Sweden)

Xiao M

2017-10-01

Full Text Available Meng Xiao,1,* Jing-Wei Cheng,1,2,* Timothy Kudinha,3 Fanrong Kong,4 Ying-Chun Xu1,21Department of Clinical Laboratory, Peking Union Medical College Hospital, 2Faculty of Clinical Laboratory Diagnostics, Graduate School, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China; 3School of Biomedical Sciences, The Charles Sturt University, Leeds Parade, Orange, 4Centre for Infectious Diseases and Microbiology Laboratory Services, ICPMR–Pathology West, Westmead Hospital, University of Sydney, Westmead, NSW, Australia*These authors contributed equally to this workIn a recent report, Dingle et al showed that national intervention programs aimed at judicious antimicrobial usage, especially restrictions to fluoroquinolones, contributed to a significant decrease in Clostridium difficile infection (CDI in England.1 This is considered an outstanding achievement in combating antimicrobial resistance worldwide.

Phase contrast imaging measurements of reversed shear Alfvén eigenmodes during sawteeth in Alcator C-Moda)

Science.gov (United States)

Edlund, E. M.; Porkolab, M.; Kramer, G. J.; Lin, L.; Lin, Y.; Wukitch, S. J.

2009-05-01

Reversed shear Alfvén eigenmodes (RSAEs) have been observed with the phase contrast imaging diagnostic and Mirnov coils during the sawtooth cycle in Alcator C-mod [M. Greenwald et al., Nucl. Fusion 45, S109 (2005)] plasmas with minority ion-cyclotron resonance heating. Both down-chirping RSAEs and up-chirping RSAEs have been observed during the sawtooth cycle. Experimental measurements of the spatial structure of the RSAEs are compared to theoretical models based on the code NOVA [C. Z. Cheng and M. S. Chance, J. Comput. Phys. 71, 124 (1987)] and used to derive constraints on the q profile. It is shown that the observed RSAEs can be understood by assuming a reversed shear q profile (up chirping) or a q profile with a local maximum (down chirping) with q ≈1.

Intelligence quotient discrepancy indicates levels of motor competence in preschool children at risk for developmental delays

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Yu TY

2016-02-01

Full Text Available Tzu-Ying Yu,1 Kuan-Lin Chen,2,3 Willy Chou,4,5 Shu-Han Yang,4 Sheng-Chun Kung,4 Ya-Chen Lee,2 Li-Chen Tung4,6,7 1Department of Occupational Therapy, College of Medicine, I-Shou University, Kaohsiung, 2Department of Occupational Therapy, College of Medicine, National Cheng Kung University, Tainan, 3Department of Physical Medicine and Rehabilitation, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, 4Department of Physical Medicine and Rehabilitation, Chi-Mei Medical Center, Tainan, 5Department of Recreation and Health Care Management, Cha Nan University of Pharmacy and Science, Tainan, 6School of Medicine, Kaohsiung Medical University, Kaohsiung, 7School of Medicine, Chung Shan Medical University, Taichung, Taiwan Purpose: This study aimed to establish 1 whether a group difference exists in the motor competence of preschool children at risk for developmental delays with intelligence quotient discrepancy (IQD; refers to difference between verbal intelligence quotient [VIQ] and performance intelligence quotient [PIQ] and 2 whether an association exists between IQD and motor competence.Methods: Children’s motor competence and IQD were determined with the motor subtests of the Comprehensive Developmental Inventory for Infants and Toddlers and Wechsler Preschool and Primary Scale of Intelligence™ – Fourth Edition. A total of 291 children were included in three groups: NON-IQD (n=213; IQD within 1 standard deviation [SD], VIQ>PIQ (n=39; VIQ>PIQ greater than 1 SD, and PIQ>VIQ (n=39; PIQ>VIQ greater than 1 SD.Results: The results of one-way analysis of variance indicated significant differences among the subgroups for the “Gross and fine motor” subdomains of the Comprehensive Developmental Inventory for Infants and Toddlers, especially on the subtests of “body-movement coordination” (F=3.87, P<0.05 and “visual-motor coordination” (F=6.90, P<0.05. Motor competence was significantly

Advances in one-dimensional wave mechanics towards a unified classical view

CERN Document Server

Cao, Zhuangqi

2014-01-01

Advances in One-Dimensional Wave Mechanics provides a comprehensive description of the motion of microscopic particles in one-dimensional, arbitrary-shaped potentials based on the analogy between Quantum Mechanics and Electromagnetism. Utilizing a deeper understanding of the wave nature of matter, this book introduces the concept of the scattered sub-waves and a series of new analytical results using the Analytical Transfer Matrix (ATM) method. This work will be useful for graduate students majoring in physics, mainly in basic quantum theory, as well as for academic researchers exploring electromagnetism, particle physics, and wave mechanics and for experts in the field of optical waveguide and integrated optics. Prof. Zhuangqi Cao is a Professor of Physics at Shanghai Jiao Tong University, China. Dr. Cheng Yin is a teacher at Jiangsu Key Laboratory of Power Transmission and Distribution Equipment Technology, Hohai University, China.

Dietary supplementation of garlic and rosemary: effects on colour stability and lipid oxidation in lamb meat

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M. Scafizzari

2010-01-01

Full Text Available The colour of fresh meat is an important criterion consumers take into consideration when purchasing meat. Meat colour depends on the occurrence of chemical and microbial deterioration processes. The role of vitamin E and other antioxidants on ruminant meat colour stability and prevention of lipid oxidation has been widely investigated (Macit et al., 2003; Realini et al., 2004. Many natural herbs and plant extracts exert antioxidant effects such as garlic (Yin and Cheng, 2003 and rosemary (Sánchez-Escalante et al., 2001. Their use as additives for animal feeding may be a valid alternative to synthetic antioxidants since they show beneficial effects also on animal welfare and other physiological functions (Tedesco, 2001. The aim of this study was to evaluate whether garlic and rosemary dietary supplementation as compared with vitamin E affects lamb meat colour and lipid stability during storage.

Magnetic levitation/suspension system by high-temperature superconducting materials

International Nuclear Information System (INIS)

Chen, I.; Hsu, J.; Jamn, G.; Lin, C.E.; Wu, M.K.

1997-01-01

Recently, with the advance of materials processing techniques, such as top-seeding and melt-texturing (TSMT) method, very large single-grained Y-Ba-Cu-O (YBCO) samples up to several centimeters in diameter can be produced. Each sample is capable of levitating over kilograms of weight. A HTS magnetic levitation (MagLev) transportation prototype has been constructed at National Cheng-Kung University (NCKU) to validate the concept of HTS-MagLev system based on Meissner effect. This HTS-MagLev is an inherent stable levitation system, unlike traditional MagLev system that requires sensors and feedback circuits to dynamically adjust its unstable levitation position. In this report, the results of various magnetic levitation parameters, such as different permanent magnet configurations, relative levitation stability, levitation force, etc., as well as magnetic field intensity and distribution will be discussed. copyright 1997 American Institute of Physics

Sodium valproate-induced enuresis in a pediatric bipolar patient

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Cheng W

2013-10-01

Full Text Available Wentao Cheng,1,* Xiaoling Lin,2,* Dali Lu1 1Department of Pediatric and Geriatric Psychiatry, Fuzhou Neuropsychiatric Hospital, Fuzhou, Fujian, People's Republic of China; 2School of Nursing of Central South University, Changsha, Hunan, People's Republic of China *These authors contributed equally to this work Abstract: Sodium valproate (SV is effective and well tolerated for the treatment of epilepsy and mood disorders. There are several cases of SV-induced enuresis noted in epileptic patients. No alternative medication has been suggested to manage this problem. We present the first case of a pediatric bipolar patient who developed diurnal and nocturnal enuresis during SV therapy. Clinicians should be aware of this side effect, as it has not been reported in nonepileptic patients, and it may be detrimental to treatment adherence. Keywords: sodium valproate, enuresis, bipolar disorder

Chinese school teachers' organizational citizenship behavior (OCB): Predictors and outcomes.

Science.gov (United States)

Li, Xia

2013-08-01

Teacher's organizational citizenship behavior (OCB) is a multifaceted construct that is critical to school effectiveness and to the education enterprise. Four hundred ninety-three teachers in eight different cities on the Chinese mainland were surveyed using the OCB scale developed by Bo Shiuan Cheng, a Taiwanese scholar. The antecedent and outcome variables of OCB were examined in this study. The results showed that the teachers' attitudinal characteristics of career satisfaction and career commitment, and the dispositional characteristic of locus of control, influenced teachers' OCB. In addition, teachers' OCB influenced their work performance as well as their career and organizational turnover intention. The implications of this study suggest a base of knowledge from which school administrators could enhance their school's organizational function and retain teachers. © 2013 The Institute of Psychology, Chinese Academy of Sciences and Wiley Publishing Asia Pty Ltd.

Ssk or Esw? -- the Bloor-Lynch Debate Revisited

Science.gov (United States)

Cheng, Kai-Yuan

2014-03-01

Philosophical discussions of rule-following in the later Wittgenstein (1953, 1967) are an important source of inspiration for the development of views on the social nature of scientific knowledge. Two major opposing views in this inquiry -- Bloor's sociology of scientific knowledge (SSK) (1983, 1991, 1992, 1997) and Lynch's (1992, 1993) ethnomethodological studies of work (ESW) -- represent two positions derived from two different readings of Wittgenstein's later writings on rule-following. The aim of this paper is two-fold. One is to re-examine the noted Bloor-Lynch debate by considering Kusch's (2004) recent discussion of this debate. Another is to show that a new semantic framework of rule-following ascriptions based on a cognitive approach to the study of generics can be provided such that SSK and ESW are compatible in it (Leslie, 2009; Cheng, 2011).

Cyclooxygenase-2 inhibitor is a robust enhancer of anticancer agents against hepatocellular carcinoma multicellular spheroids

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Cui J

2014-02-01

Full Text Available Jie Cui,1,2 Ya-Huan Guo,3 Hong-Yi Zhang,4 Li-Li Jiang,1 Jie-Qun Ma,1 Wen-Juan Wang,1 Min-Cong Wang,1 Cheng-Cheng Yang,1 Ke-Jun Nan,1 Li-Ping Song5 1Department of Oncology, First Affiliated Hospital, College of Medicine of Xi'an Jiaotong University, Xi'an, 2Department of Oncology, Yan'an University Affiliated Hospital, Yan'an, 3Department of Oncology, Shaanxi Province Cancer Hospital, Xi'an, 4Department of Urology, Yan'an University Affiliated Hospital, Yan'an, 5Department of Radiotherapy, First Affiliated Hospital, College of Medicine of Xi'an Jiaotong University, Xi'an, People's Republic of China Purpose: Celecoxib, an inhibitor of cyclooxygenase-2 (COX2, was investigated for enhancement of chemotherapeutic efficacy in cancer clinical trials. This study aimed to determine whether celecoxib combined with 5-fluorouracil or sorafenib or gefitinib is beneficial in HepG2 multicellular spheroids (MCSs, as well as elucidate the underlying mechanisms. Methods: The human hepatocellular carcinoma cell line HepG2 MCSs were used as in vitro models to investigate the effects of celecoxib combined with 5-fluorouracil or sorafenib or gefitinib treatment on cell growth, apoptosis, and signaling pathway. Results: MCSs showed resistance to drugs compared with monolayer cells. Celecoxib combined with 5-fluorouracil or sorafenib exhibited a synergistic action. Exposure to celecoxib (21.8 µmol/L plus 5-fluorouracil (8.1 × 10-3 g/L or sorafenib (4.4 µmol/L increased apoptosis but exerted no effect on COX2, phosphorylated epidermal growth-factor receptor (p-EGFR and phosphorylated (p-AKT expression. Gefitinib (5 µmol/L, which exhibits no growth-inhibition activity as a single agent, increased the inhibitory effect of celecoxib. Gefitinib (5 µmol/L plus celecoxib (21.8 µmol/L increased apoptosis. COX2, p-EGFR, and p-AKT were inhibited. Conclusion: Celecoxib combined with 5-fluorouracil or sorafenib or gefitinib may be superior to single-agent therapy in HepG2

Preparation and functional studies of hydroxyethyl chitosan nanoparticles loaded with anti-human death receptor 5 single-chain antibody

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Yang J

2014-05-01

Full Text Available Jingjing Yang,1,3,* Xiaoping Huang,1,3,* Fanghong Luo,1 Xiaofeng Cheng,3 Lianna Cheng,3 Bin Liu,4 Lihong Chen,2 Ruyi Hu,1,3 Chunyan Shi,1,3 Guohong Zhuang,1,3 Ping Yin2 1Anti-Cancer Research Center, Medical College, Xiamen University, Fujian, People's Republic of China, 2The Department of Pathology, Zhongshan Hospital, Xiamen University, Xiamen, People's Republic of China, 3Organ transplantation institution, Xiamen University, Xiamen, People's Republic of China, 4Jilin Vocational College of Industry and Technology, Jilin, People's Republic of China  *These authors contributed equally to this work Objective: To prepare hydroxyethyl chitosan nanoparticles loaded with anti-human death receptor 5 single-chain antibody, and study their characteristics, functions, and mechanisms of action. Materials and methods: The anti-human death receptor 5 single-chain antibody was constructed and expressed. Protein-loaded hydroxyethyl chitosan nanoparticles were prepared, and their size, morphology, particle-size distribution and surface zeta potential were measured by scanning electron microscopy and laser particle-size analysis. Mouse H22 hepatocellular carcinoma cells were cultured, and growth inhibition was examined using the CellTiter-Blue cell-viability assay. Flow cytometry and Hoechst 33342 were employed to measure cell apoptosis. Kunming mice with H22 tumor models were treated with protein-loaded hydroxyethyl chitosan nanoparticles, and their body weight and tumor size were measured, while hematoxylin and eosin staining was used to detect antitumor effects in vivo and side effects from tumors. Results: The protein-loaded hydroxyethyl chitosan nanoparticles had good stability; the zeta potential was -24.2±0.205, and the dispersion index was 0.203. The inhibition of the protein-loaded hydroxyethyl chitosan nanoparticles on H22 growth was both time- and dose-dependent. Increased expressions of active caspase 8, active caspase 3, and BAX were detected

Cordycepin enhances cisplatin apoptotic effect through caspase/MAPK pathways in human head and neck tumor cells

Directory of Open Access Journals (Sweden)

Chen YH

2013-07-01

Full Text Available Ying-Hui Chen,1,2,* Jo-Yu Wang,3,* Bo-Syong Pan,3,4 Yi-Fen Mu,3 Meng-Shao Lai,3,4 Edmund Cheung So,5 Thian-Sze Wong,6 Bu-Miin Huang3,4 1Department of Anesthesia, Chi-Mei Medical Center, Liouying, 2Department of Nursing, Min-Hwei College of Health Care Management, 3Department of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, 4The Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, 5Department of Anesthesia, An Nan Hospital, China Medical University, Tainan, Taiwan; 6Department of Surgery, University of Hong Kong Medical Center, Faculty of Medicine, The University of Hong Kong, Hong Kong *Authors contributed equally to this work Purpose: The present study aims to investigate whether the combination treatment of cordycepin (an extracted pure compound from Cordyceps sinensis and cisplatin (a platinum-based chemotherapy drug has better apoptotic effect in head and neck squamous cell carcinoma (HNSCC. Methods: The apoptotic influences of cordycepin and/or cisplatin treatments to human OC3, OEC-M1, and FaDu HNSCC cells were investigated by morphological observations, viability assay, flow cytometry assay, and Western blotting methods. Results: Data showed that the cell death phenomenon increased as the dosage of cordycepin or cisplatin increased, and it appeared more in cordycepin plus cisplatin cotreatment among three cell lines. Cell survival rates significantly decreased as the dosage of cordycepin or cisplatin increased, and the better apoptotic effects were observed in cotreatment. Cell cycle analysis further demonstrated that percentages of subG1 cells in cordycepin or cisplatin treatments significantly increased, suggesting that cells underwent apoptosis, and cordycepin plus cisplatin induced many more subG1 cells. Furthermore, cordycepin or cisplatin induced caspase-8, caspase-9, caspase-3, and poly adenosine diphosphate-ribose polymerase protein cleavages, and stimulated c

Development of solid lipid nanoparticles containing total flavonoid extract from Dracocephalum moldavica L. and their therapeutic effect against myocardial ischemia–reperfusion injury in rats

Directory of Open Access Journals (Sweden)

Tan ME

2017-04-01

Full Text Available Mei-e Tan,1–3,* Cheng-hui He,3,* Wen Jiang,4 Cheng Zeng,2–4 Ning Yu,3 Wei Huang,2 Zhong-gao Gao,2 Jian-guo Xing3 1Key Laboratory of Xinjiang Endemic Phytomedicine Resources of Ministry of Education, School of Pharmacy, Shihezi University, Shihezi, 2State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Department of Pharmaceutics, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 3Xinjiang Key Laboratory of Uighur Medicines, Xinjiang Institute of Materia Medica, 4Xinjiang Medical University, Urumqi, People’s Republic of China *These authors contributed equally to this work Abstract: Total flavonoid extract from Dracocephalum moldavica L. (TFDM contains effective components of D. moldavica L. that have myocardial protective function. However, the cardioprotection function of TFDM is undesirable due to its poor solubility. In order to improve the solubility and efficacy of TFDM, we developed TFDM-loaded solid lipid nanoparticles (TFDM-SLNs and optimized the formulation of TFDM-SLNs using central composite design and response surface methodology. The physicochemical properties of TFDM-SLNs were characterized, and the pharmacodynamics was investigated using the myocardial ischemia–reperfusion injury model in rats. The nanoparticles of optimal formulation for TFDM-SLNs were spherical in shape with the average particle size of 104.83 nm and had a uniform size distribution with the polydispersity index value of 0.201. TFDM-SLNs also had a negative zeta potential of -28.7 mV to ensure the stability of the TFDM-SLNs emulsion system. The results of pharmacodynamics demonstrated that both TFDM and TFDM-SLN groups afforded myocardial protection, and the protective effect of TFDM-SLNs was significantly superior to that of TFDM alone, based on the infarct area, histopathological examination, cardiac enzyme levels and inflammatory factors in serum. Due to the optimal

Multifractal characteristics of NDVI maps in space and time in the Community of Madrid (Spain)

Science.gov (United States)

Sotoca, Juan J. Martin; Saa-Requejo, Antonio; Grau, Juan B.; Tarquis, Ana M.

2015-04-01

Satellite information has contributed to improve our understanding of the spatial variability of hydro-climatic and ecological processes. Vegetation activity is tightly coupled with climate, hydro-ecological fluxes, and terrain dynamics in river basins at a wide range of space-time scales (Scheuring and Riedi, 1994). Indices of vegetation activity are constructed using satellite information of reflectance of the relevant spectral bands which enhance the contribution of vegetation being Normalized Difference Vegetation Index (NDVI) widely used. How can we study such a complex system? Multifractals and fractals are related techniques mainly used in physics to characterize the scaling behaviour of a system; they differ in that fractals look at the geometry of presence/absence patterns, while multifractals look at the arrangement of quantities such as population or biomass densities (Saravia et al., 2012). Scaling laws are an emergent general feature of ecological systems; they reflect constraints in their organization that can provide tracks about the underlying mechanisms (Solé and Bascompte, 2006). In this work, we have applied these techniques to study the spatial pattern through one year of NDVI maps. A rectangular area that includes the Community of Madrid and part of the surroundings, consisting of 300 x 280 pixels with a resolution of 500 x 500 m2 has been selected and monthly NDVI maps analyzed using the multifractal spectrum and the map of singularities (Cheng and Agterberg, 1996). The results show a cyclical pattern in the multifractal behaviour and singularity points related to river basin networks (Martín-Sotoca, 2014). References Cheng, Q. and Agterberg, F.P. (1996). Multifractal modeling and spatial statistics. Math. Geol. Vol 28, 1-16. Martín-Sotoca, J.J. (2014) Estructura Espacial de la Sequía en Pastos y sus Aplicaciones en el Seguro Agrario. Master Thesis, UPM (In Spanish). Saravia LA, Giorgi A, Momo F.: Multifractal growth in periphyton

Use of Openly Available Satellite Images for Remote Sensing Education

Science.gov (United States)

Wang, C.-K.

2011-09-01

With the advent of Google Earth, Google Maps, and Microsoft Bing Maps, high resolution satellite imagery are becoming more easily accessible than ever. It have been the case that the college students may already have wealth experiences with the high resolution satellite imagery by using these software and web services prior to any formal remote sensing education. It is obvious that the remote sensing education should be adjusted to the fact that the audience are already the customers of remote sensing products (through the use of the above mentioned services). This paper reports the use of openly available satellite imagery in an introductory-level remote sensing course in the Department of Geomatics of National Cheng Kung University as a term project. From the experience learned from the fall of 2009 and 2010, it shows that this term project has effectively aroused the students' enthusiastic toward Remote Sensing.

A taxonomic synopsis of Altingiaceae with nine new combinations

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Stefanie Ickert-Bond

2013-12-01

Full Text Available A taxonomic synopsis of the Altingiaceae is presented, including the taxonomic enumeration and distribution of 15 recognized species based on studies of 1,500 specimens from 24 herbaria throughout the distributional range of the taxa. Previous phylogenetic analyses based on several molecular markers have shown that Altingia and Semiliquidambar are nested within Liquidambar. All Altingia and Semiliquidambar species are now formally transferred to Liquidambar, which has the nomenclatural priority. The following nine new combinations are herein made: Liquidambar cambodiana (Lecomte Ickert-Bond & J. Wen, L. caudata (H. T. Chang Ickert-Bond & J. Wen, L. chingii (Metcalf Ickert-Bond & J. Wen, L. gracilipes (Hemsl. Ickert-Bond & J. Wen, L. multinervis (Cheng Ickert-Bond & J. Wen, L. obovata (Merrill & Chun Ickert-Bond & J. Wen, L. poilanei (Tardieu Ickert-Bond & J. Wen, L. siamensis (Craib Ickert-Bond & J. Wen, and L. yunnanensis (Rehder & Wilson Ickert-Bond & J. Wen.

A second order discontinuous Galerkin fast sweeping method for Eikonal equations

Science.gov (United States)

Li, Fengyan; Shu, Chi-Wang; Zhang, Yong-Tao; Zhao, Hongkai

2008-09-01

In this paper, we construct a second order fast sweeping method with a discontinuous Galerkin (DG) local solver for computing viscosity solutions of a class of static Hamilton-Jacobi equations, namely the Eikonal equations. Our piecewise linear DG local solver is built on a DG method developed recently [Y. Cheng, C.-W. Shu, A discontinuous Galerkin finite element method for directly solving the Hamilton-Jacobi equations, Journal of Computational Physics 223 (2007) 398-415] for the time-dependent Hamilton-Jacobi equations. The causality property of Eikonal equations is incorporated into the design of this solver. The resulting local nonlinear system in the Gauss-Seidel iterations is a simple quadratic system and can be solved explicitly. The compactness of the DG method and the fast sweeping strategy lead to fast convergence of the new scheme for Eikonal equations. Extensive numerical examples verify efficiency, convergence and second order accuracy of the proposed method.

Validation of Numerical Two-Fluid and Kinetic Plasma Models

Energy Technology Data Exchange (ETDEWEB)

Daniel Barnes

2011-03-25

This was a four year grant commencing October 1, 2003 and finishing September 30, 2007. The funding was primarily used to support the work of the Principal Investigator, who collaborated with Profs. Scott Parker and John Cary at U. Colorado, and with two students, N. Xiang and J. Cheng also of U. Colorado. The technical accomplishments of this grant can be found in the publications listed in the final Section here. The main accomplishments of the grant work were: (1) Development and implementation of time-implicit two-fluid simulation methods in collaboration with the NIMROD team; and (2) Development and testing of a new time-implicit delta-f, energy-conserving method The basic two-fluid method, with many improvements is used in present NIMROD calculations. The energy-conserving delta-f method is under continuing development under contract between Coronado Consulting, a New Mexico sole proprietorship and the Oak Ridge National Laboratory.

Validation of Numerical Two-Fluid and Kinetic Plasma Models. Final Report

International Nuclear Information System (INIS)

Barnes, Daniel

2011-01-01

This was a four year grant commencing October 1, 2003 and finishing September 30, 2007. The funding was primarily used to support the work of the Principal Investigator, who collaborated with Profs. Scott Parker and John Cary at U. Colorado, and with two students, N. Xiang and J. Cheng also of U. Colorado. The technical accomplishments of this grant can be found in the publications listed in the final Section here. The main accomplishments of the grant work were: (1) Development and implementation of time-implicit two-fluid simulation methods in collaboration with the NIMROD team; and (2) Development and testing of a new time-implicit delta-f, energy-conserving method The basic two-fluid method, with many improvements is used in present NIMROD calculations. The energy-conserving delta-f method is under continuing development under contract between Coronado Consulting, a New Mexico sole proprietorship and the Oak Ridge National Laboratory.

Lanthanide metal-organic frameworks

International Nuclear Information System (INIS)

Cheng, Peng

2015-01-01

This book contains the following nine chapters: lanthanide metal-organic frameworks: syntheses, properties, and potential applications (Stephen Fordham, Xuan Wang, Mathieu Bosch, Hong-Cai Zhou); 2. chiral lanthanide metal-organic frameworks (Weisheng Liu, Xiaoliang Tang); 3. Porous lanthanide metal-organic frameworks for gas storage and separation (Bin Li, Banglin Chen); 4. Luminescent lanthanide metal-organic frameworks (Xue-Zhi Song, Shu-Yan Song, Hong-Jie Zhang); 5. Metal-organic frameworks based on lanthanide clusters (Lian Chen, Feilong Jiang, Kang Zhou, Mingyan Wu, Maochun Hong); 6. metal-organic frameworks with d-f cyanide bridges: structural diversity, bonding regime, and magnetism (Marilena Ferbinteanu, Fanica Cimpoesu, Stefania Tanase); 7. transition-lanthanide heterometal-organic frameworks: synthesis, structures, and properties (Wei Shi, Ke Liu, Peng Cheng); 8: MOFs of uranium and the actinides (Juan Su, Jiesheng Chen); 9. Nanostructured and/or nanoscale lanthanide metal-organic frameworks (Zhonghao Zhang, Zhiping Zheng).

International Workshop on "Intersubband Transitions in Quantum Wells : Physics and Applications"

CERN Document Server

Su, Yan-Kuin

1998-01-01

The International Workshop on "Intersubband Transitions in Quantum Wells:: Physics and Applications," was held at National Cheng Kung University, in Tainan, Taiwan, December 15-18, 1997. The objective of the Workshop is to facilitate the presentation and discussion of the recent results in theoretical, experimental, and applied aspects of intersubband transitions in quantum wells and dots. The program followed the tradition initiated at the 1991 conference in Cargese-France, the 1993 conference in Whistler, B. C. Canada, and the 1995 conference in Kibbutz Ginosar, Israel. Intersubband transitions in quantum wells and quantum dots have attracted considerable attention in recent years, mainly due to the promise of various applications in the mid- and far-infrared regions (2-30 J. lm). Over 40 invited and contributed papers were presented in this four-day workshop, with topics covered most aspects of the intersubband transition phenomena including: the basic intersubband transition processes, multiquantum well i...

A college course on relativity and cosmology

CERN Document Server

Cheng, Ta-Pei

2015-01-01

This advanced undergraduate text introduces Einstein's general theory of relativity. The topics covered include geometric formulation of special relativity, the principle of equivalence, Einstein's field equation and its spherical-symmetric solution, as well as cosmology. An emphasis is placed on physical examples and simple applications without the full tensor apparatus. It begins by examining the physics of the equivalence principle and looks at how it inspired Einstein's idea of curved spacetime as the gravitational field. At a more mathematically accessible level, it provides a metric description of a warped space, allowing the reader to study many interesting phenomena such as gravitational time dilation, GPS operation, light deflection, precession of Mercury's perihelion, and black holes. Numerous modern topics in cosmology are discussed from primordial inflation and cosmic microwave background to the dark energy that propels an accelerating universe. Building on Cheng's previous book, 'Relativity, Grav...

Applied methods and techniques for mechatronic systems modelling, identification and control

CERN Document Server

Zhu, Quanmin; Cheng, Lei; Wang, Yongji; Zhao, Dongya

2014-01-01

Applied Methods and Techniques for Mechatronic Systems brings together the relevant studies in mechatronic systems with the latest research from interdisciplinary theoretical studies, computational algorithm development and exemplary applications. Readers can easily tailor the techniques in this book to accommodate their ad hoc applications. The clear structure of each paper, background - motivation - quantitative development (equations) - case studies/illustration/tutorial (curve, table, etc.) is also helpful. It is mainly aimed at graduate students, professors and academic researchers in related fields, but it will also be helpful to engineers and scientists from industry. Lei Liu is a lecturer at Huazhong University of Science and Technology (HUST), China; Quanmin Zhu is a professor at University of the West of England, UK; Lei Cheng is an associate professor at Wuhan University of Science and Technology, China; Yongji Wang is a professor at HUST; Dongya Zhao is an associate professor at China University o...

Lanthanide metal-organic frameworks

Energy Technology Data Exchange (ETDEWEB)

Cheng, Peng (ed.) [Nankai Univ., Tianjin (China). Dept. of Chemistry

2015-03-01

This book contains the following nine chapters: lanthanide metal-organic frameworks: syntheses, properties, and potential applications (Stephen Fordham, Xuan Wang, Mathieu Bosch, Hong-Cai Zhou); 2. chiral lanthanide metal-organic frameworks (Weisheng Liu, Xiaoliang Tang); 3. Porous lanthanide metal-organic frameworks for gas storage and separation (Bin Li, Banglin Chen); 4. Luminescent lanthanide metal-organic frameworks (Xue-Zhi Song, Shu-Yan Song, Hong-Jie Zhang); 5. Metal-organic frameworks based on lanthanide clusters (Lian Chen, Feilong Jiang, Kang Zhou, Mingyan Wu, Maochun Hong); 6. metal-organic frameworks with d-f cyanide bridges: structural diversity, bonding regime, and magnetism (Marilena Ferbinteanu, Fanica Cimpoesu, Stefania Tanase); 7. transition-lanthanide heterometal-organic frameworks: synthesis, structures, and properties (Wei Shi, Ke Liu, Peng Cheng); 8: MOFs of uranium and the actinides (Juan Su, Jiesheng Chen); 9. Nanostructured and/or nanoscale lanthanide metal-organic frameworks (Zhonghao Zhang, Zhiping Zheng).

Possible manifestation of long range forces in high energy hadron collisions

International Nuclear Information System (INIS)

Kuraev, Eh.A.; Ferro, P.; Trentadue, L.

1997-01-01

Pion-pion and photon-photon scattering are discussed.. We obtain, starting from the impact representation introduced by Cheng and Wu a new contribution to the high energy hadron-hadron scattering amplitude for small transferred momentum q 2 of the form is (q 2 /m 4 )ln(-q 2 /m 2 ). This behaviour may be interpreted as a manifestation of long transverse-range forces between hadrons which, for ρ>> m -1 fall off as ρ -4 . We consider the examples of pion and photon scattering with photons converted in the intermediate state to two pairs of quarks interacting by exchanging two gluon colorless state. A phenomenological approach for proton impact factor is used to analyze proton-proton scattering. The analysis of the lowest order radiative corrections for the case of photon-photon scattering is done. We discuss the possibility of observing the effects of these long range forces

Erratum!- in paper volume 19, Supplement 1, Year 2015, pp. S109-S115, DOI:10.2298/TSCI15S1S09C

Directory of Open Access Journals (Sweden)

Editorial

2015-01-01

Full Text Available In the paper published in THERMAL SCIENCE Volume 19, Supplement 1, YEAR 2015, pp. S109-S115, DOI REFERENCE: 10.2298/TSCI15S1S09C Names and affiliations of the authors has been incorrectly written Istead of: THE DIFFUSION MODEL OF FRACTAL HEAT AND MASS TRANSFER IN FLUIDIZED BED A Local Fractional Arbitrary Euler-Lagrange Formula by Xu CHENG∗ and Xiao-Xun MA School of Chemical Engineering, Northwest University, Xi'an, Shaanxi, China Correctly has to be written: THE DIFFUSION MODEL OF FRACTAL HEAT AND MASS TRANSFER IN FLUIDIZED BED A Local Fractional Arbitrary Euler-Lagrange Formula by Xu CHENG1∗ and Lin Wang2 - 1School of Chemical Engineering, Northwest University, Xi'an, Shaanxi, China - 2Xi'an Modern Chemistry Research Institute, Xi'an, Shaanxi, China Link to the corrected article 10.2298/TSCI15S1S09C

Empirical atom model of Vegard's law

International Nuclear Information System (INIS)

Zhang, Lei; Li, Shichun

2014-01-01

Vegard's law seldom holds true for most binary continuous solid solutions. When two components form a solid solution, the atom radii of component elements will change to satisfy the continuity requirement of electron density at the interface between component atom A and atom B so that the atom with larger electron density will expand and the atom with the smaller one will contract. If the expansion and contraction of the atomic radii of A and B respectively are equal in magnitude, Vegard's law will hold true. However, the expansion and contraction of two component atoms are not equal in most situations. The magnitude of the variation will depend on the cohesive energy of corresponding element crystals. An empirical atom model of Vegard's law has been proposed to account for signs of deviations according to the electron density at Wigner–Seitz cell from Thomas–Fermi–Dirac–Cheng model

Strengthening the case that elevated levels of programmed death ligand 1 predict poor prognosis in hepatocellular carcinoma patients

Directory of Open Access Journals (Sweden)

Zhong J

2016-12-01

Full Text Available Jian-Hong Zhong,1,* Cheng-Piao Luo,2,* Chun-Yan Zhang,2 Le-Qun Li1 1Hepatobiliary Surgery Department, 2Experimental Department, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, People’s Republic of China *These authors contributed equally to this work Abstract: Immunotherapy targeting programmed death receptor 1 and programmed death ligand 1 (PD-L1 has shown impressive antitumor efficacy in several solid cancers, including advanced hepatocellular carcinoma (HCC. Since response rates of various cancers to such immunotherapy appear to correlate with PD-L1 expression levels, several studies have examined whether PD-L1 expression correlates with HCC pathology and patient prognosis. In this paper, we analyzed the strength and limitations of a recent meta-analysis of associations of PD-L1 with HCC characteristics and patient prognosis. Keywords: hepatocellular carcinoma, programmed death ligand 1, hepatic resection, prognoses

P value and the theory of hypothesis testing: an explanation for new researchers.

Science.gov (United States)

Biau, David Jean; Jolles, Brigitte M; Porcher, Raphaël

2010-03-01

In the 1920s, Ronald Fisher developed the theory behind the p value and Jerzy Neyman and Egon Pearson developed the theory of hypothesis testing. These distinct theories have provided researchers important quantitative tools to confirm or refute their hypotheses. The p value is the probability to obtain an effect equal to or more extreme than the one observed presuming the null hypothesis of no effect is true; it gives researchers a measure of the strength of evidence against the null hypothesis. As commonly used, investigators will select a threshold p value below which they will reject the null hypothesis. The theory of hypothesis testing allows researchers to reject a null hypothesis in favor of an alternative hypothesis of some effect. As commonly used, investigators choose Type I error (rejecting the null hypothesis when it is true) and Type II error (accepting the null hypothesis when it is false) levels and determine some critical region. If the test statistic falls into that critical region, the null hypothesis is rejected in favor of the alternative hypothesis. Despite similarities between the two, the p value and the theory of hypothesis testing are different theories that often are misunderstood and confused, leading researchers to improper conclusions. Perhaps the most common misconception is to consider the p value as the probability that the null hypothesis is true rather than the probability of obtaining the difference observed, or one that is more extreme, considering the null is true. Another concern is the risk that an important proportion of statistically significant results are falsely significant. Researchers should have a minimum understanding of these two theories so that they are better able to plan, conduct, interpret, and report scientific experiments.

Artificial Intelligence and the Future of Education: Big Promises-Bigger Challenges%Artificial Intelligence and the Future of Education:Big Promises-Bigger Challenges

Institute of Scientific and Technical Information of China (English)

Jonathan Michael Spector; Du Jing

2017-01-01

The history of educational technology in the last 50 years contains few instances of dramatic improvements in learning based on the adoption of a particular technology.An example involving artificial intelligence occurred in the 1990s with the development of intelligent tutoring systems (ITSs).What happened with ITSs was that their success was limited to well-defined and relatively simple declarative and procedural leaming tasks (e.g.,learning how to write a recursive function in LISP;doing multi-column addition),and improvements that were observed tended to be more limited than promised (e.g.,one standard deviation improvement at best rather than the promised standard deviation improvement).Still,there was some progress in terms of how to conceptualize learning.A seldom documented limitation was the notion of only viewing learning from only content and cognitive perspectives (i.e.,in terms of memory limitations,prior knowledge,bug libraries,learning hierarchies and sequences etc.).Little attention was paid to education conceived more broadly than developing specific cognitive skills with highly constrained problems.New technologies offer the potential to create dynamic and multi-dimensional models of a particular leamer,and to track large data sets of learning activities,resources,interventions,and outcomes over a great many leamers.Using those data to personalize learning for a particular leamer developing knowledge,competence and understanding in a specific domain of inquiry is finally a real possibility.While the potential to make significant progress is clearly possible,the reality is less not so promising.There are many as yet unmet challenging some of which will be mentioned in this paper.A persistent worry is that educational technologists and computer scientists will again promise too much,too soon at too little cost and with too little effort and attention to the realities in schools and universities.

The impact of xylem cavitation on water potential isotherms measured by the pressure chamber technique in Metasequoia glyptostroboides Hu & W.C. Cheng.

Science.gov (United States)

Yang, Dongmei; Pan, Shaoan; Tyree, Melvin T

2016-08-01

Pressure-volume (PV) curve analysis is the most common and accurate way of estimating all components of the water relationships in leaves (water potential isotherms) as summarized in the Höfler diagram. PV curve analysis yields values of osmotic pressure, turgor pressure, and elastic modulus of cell walls as a function of relative water content. It allows the computation of symplasmic/apoplastic water content partitioning. For about 20 years, cavitation in xylem has been postulated as a possible source of error when estimating the above parameters, but, to the best of the authors' knowledge, no one has ever previously quantified its influence. Results in this paper provide independent estimates of osmotic pressure by PV curve analysis and by thermocouple psychrometer measurement. An anatomical evaluation was also used for the first time to compare apoplastic water fraction estimates from PV analysis with anatomical values. Conclusions include: (i) PV curve values of osmotic pressure are underestimated prior to correcting osmotic pressure for water loss by cavitation in Metasequoia glyptostroboides; (ii) psychrometer estimates of osmotic pressure obtained in tissues killed by freezing or heating agreed with PV values before correction for apoplastic water dilution; (iii) after correction for dilution effects, a solute concentration enhancement (0.27MPa or 0.11 osmolal) was revealed. The possible sources of solute enhancement were starch hydrolysis and release of ions from the Donnan free space of needle cell walls. © The Author 2016. Published by Oxford University Press on behalf of the Society for Experimental Biology. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Self-potential chenges associated with volcanic activity: Short-term signals associated with March 9, 1998 eruption on La Fournaise volcano (Reunion Island

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P. Yvetot

2001-06-01

Full Text Available After six years of quietness La Fournaise volcano entered into activity on March 9, 1998. Fissures opened gradually downwards on the northern flank of the cone. Two cones, Kapor and Krafft built, from which lava poured until September 1998. Several other vents opened during this eruption. Mappings, surveys, and continuous recordings of the Self-Potential have been performed on the volcano for twenty years. SP mappings disclose the variability of large scale SP anomalies due to the modification of the hydrothermal system over some ten years. Most of the eruptions take place along a Main Fracture Zone (MFZ in which ground water flows prevail. SP measurements have also regularly been made on the northern flank of the cone, on a west-east profile crossing the MFZ. Between 1981 and 1992 an enlargement and a shift of the MFZ to the east are evidenced. In particular, the eastern fissural axis trending N35°E could be related to the possible collapse of the east flank of the volcano. After a decrease between 1992 and 1997, the SP anomaly was enhanced again by the 1998 eruption. Short scale, about 250 m wide, 750 mV amplitude anomalies were superimposed on a large scale one, 2500 m wide, and about 250 mV in amplitude. For several years, continuous stations have been measuring the electric field along two directions, with a 20 s sampling, in order to record the genesis of SP signals associated with the volcanic activity. Oscillations belonging to the ULF band were evidenced several days before the 1988 eruption, some of them at 9 km from the summit. Their amplitude reached several tens mV/km. These oscillations sometimes present a phase lag from one station to another; they progressively shift towards the location of the future effusive vents. The polarisation of the oscillations is similar to the polarisation of longer SP variations (1 h period or more and are correlated with the structural anisotropy. Finally, during the last hours preceding the effusive activity, huge SP signals, up to a few Volts/km, appeared at the stations located on the MFZ, and especially on the branch where the magma migrated. We interpret these SP signals as due to electrokinetic effects generated by fluid flow in cracks opened by the stress field changes.

Analysis of Movie I Am Not Stupid 2: Parenting Style 分析《小孩不笨2》电影的父母教育法

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Mariana Mariana

2015-04-01

Full Text Available This paper, through Singaporean movie I am not Stupid 2, analyzes the relation between parenting and children’s growth process and also the action of parents should do to offer children for having a good growth process. Research was done based on Baumrind theory about parenting analysis to what kind of parenting that the parents of the movie I am not Stupid 2 offer to their children. Research used literature study to summarize, arrange, and analyze of Diana Baumrind as basis of the research. The results show that Tom and Jerry’s parents or Cheng Cai’s father used authoritarian parenting style. Research suggests that the best parenting style is authoritative parenting because this type of parenting does not only concern about the prominence of rules or regulations in the family, but also the affection of parents towards the children. Therefore, the family will certainly become more harmonious. 

Recent development in clusters of rare earths and actinides. Chemistry and materials

Energy Technology Data Exchange (ETDEWEB)

Zheng, Zhiping (ed.) [Arizona Univ., Tucson, AZ (United States). Dept. of Chemistry and Biochemistry

2017-02-01

This book contains the following eight contributions: 1. Lanthanide Hydroxide Cluster Complexes via Ligand-Controlled Hydrolysis of the Lanthanide Ions (Zhonghao Zhang, Yanan Zhang, and Zhiping Zheng); 2. Synthesis and Structures of Lanthanide-Transition Metal Clusters (Xiu-Ying Zheng, Xiang-Jian Kong, and La-Sheng Long); 3. Hydrothermal Synthesis of Lanthanide and Lanthanide-Transition-Metal Cluster Organic Frameworks via Synergistic Coordination Strategy (Jian-Wen Cheng and Guo-Yu Yang); 4. Oxo Clusters of 5f Elements (Sarah Hickam and Peter C.); 5. Construction and Luminescence Properties of 4f and d-4f Clusters with Salen-Type Schiff Base Ligands (Xiaoping Yang, Shiqing Wang, Chengri Wang, Shaoming Huang, and Richard A.); 6. 4f-Clusters for Cryogenic Magnetic Cooling (Yan-Cong Chen, Jun-Liang Liu, and Ming-Liang Tong); 7. Lanthanide Clusters Toward Single-Molecule Magnets (Tian Han, You-Song Ding, and Yan-Zhen Zheng); 8. Molecular Rare Earth Hydride Clusters (Takanori Shima and Zhaomin Hou).

Investigation of the relaxor behavior of sol gel processed lanthanum lead titanium ceramics

International Nuclear Information System (INIS)

Limame, K.; Sayouri, S.; Yahyaoui, M.M.; Housni, A.; Jaber, B.

2016-01-01

A series of La doped lead titanate samples, with composition Pb_1_−_xLa_xTi_1_−_x_/_4O_3 (PLTx), where x=0.00; 0.02; 0.04; 0.06; 0.07; 0.08; 0.10; 0.12; 0.14; 0.16; 0.18; 0.21 and 0.22 was prepared using the sol–gel process. Addition of La gives rise to the two well-known phenomena: diffuseness and relaxation around the ferro-to-paraelectric transition; the two parameters related to these phenomena, and which give a satisfactory interpretation of them, have been estimated using the Uchino's quadratic law. This diffuse phase transition (DPT) has been investigated with the help of the Landau–Devonshire cluster theory and the model of Cheng et al., to show that polar regions may be generated around the DPT and far from the temperature, T_m, of the maximum of the dielectric permittivity, which have as a direct consequence a non vanishing polarization even if T>T_m.

Geometric Optimization of Thermo-electric Coolers Using Simulated Annealing

International Nuclear Information System (INIS)

Khanh, D V K; Vasant, P M; Elamvazuthi, I; Dieu, V N

2015-01-01

The field of thermo-electric coolers (TECs) has grown drastically in recent years. In an extreme environment as thermal energy and gas drilling operations, TEC is an effective cooling mechanism for instrument. However, limitations such as the relatively low energy conversion efficiency and ability to dissipate only a limited amount of heat flux may seriously damage the lifetime and performance of the instrument. Until now, many researches were conducted to expand the efficiency of TECs. The material parameters are the most significant, but they are restricted by currently available materials and module fabricating technologies. Therefore, the main objective of finding the optimal TECs design is to define a set of design parameters. In this paper, a new method of optimizing the dimension of TECs using simulated annealing (SA), to maximize the rate of refrigeration (ROR) was proposed. Equality constraint and inequality constraint were taken into consideration. This work reveals that SA shows better performance than Cheng's work. (paper)

Palaeo-adaptive properties of the xylem of Metasequoia: mechanical/hydraulic compromises.

Science.gov (United States)

Jagels, Richard; Visscher, George E; Lucas, John; Goodell, Barry

2003-07-01

The xylem of Metasequoia glyptostroboides Hu et Cheng is characterized by very low density (average specific gravity = 0.27) and tracheids with relatively large dimensions (length and diameter). The microfibril angle in the S2 layer of tracheid walls is large, even in outer rings, suggesting a cambial response to compressive rather than tensile stresses. In some cases, this compressive stress is converted to irreversible strain (plastic deformation), as evidenced by cell wall corrugations. The heartwood is moderately decay resistant, helping to prevent Brazier buckling. These xylem properties are referenced to the measured bending properties of modulus of rupture and modulus of elasticity, and compared with other low-to-moderate density conifers. The design strategy for Metasequoia is to produce a mechanically weak but hydraulically efficient xylem that permits rapid height growth and crown development to capture and dominate a wet site environment. The adaptability of these features to a high-latitude Eocene palaeoenvironment is discussed.

Palaeo‐adaptive Properties of the Xylem of Metasequoia: Mechanical/Hydraulic Compromises

Science.gov (United States)

JAGELS, RICHARD; VISSCHER, GEORGE E.; LUCAS, JOHN; GOODELL, BARRY

2003-01-01

The xylem of Metasequoia glyptostroboides Hu et Cheng is characterized by very low density (average specific gravity = 0·27) and tracheids with relatively large dimensions (length and diameter). The microfibril angle in the S2 layer of tracheid walls is large, even in outer rings, suggesting a cambial response to compressive rather than tensile stresses. In some cases, this compressive stress is converted to irreversible strain (plastic deformation), as evidenced by cell wall corrugations. The heartwood is moderately decay resistant, helping to prevent Brazier buckling. These xylem properties are referenced to the measured bending properties of modulus of rupture and modulus of elasticity, and compared with other low‐to‐moderate density conifers. The design strategy for Metasequoia is to produce a mechanically weak but hydraulically efficient xylem that permits rapid height growth and crown development to capture and dominate a wet site environment. The adaptability of these features to a high‐latitude Eocene palaeoenvironment is discussed. PMID:12763758

Thermal Conductivity of Polymer Composite poypropilene-Sand

International Nuclear Information System (INIS)

Betha; Mashuri; Sudirman; Karo Karo, Aloma

2001-01-01

Thermal conductivity composite materials polypropylene (PP)-sand have been investigated. PP composite with sand to increase thermal conductivity from the polymer. The composite in this observation is done by mixing matrix (PP melt flow 2/10)and filler sand)by means tool labo plastomil. The result of thermal conductivity is composite of PP-sand which is obtained increase and followed by the raising of filler particle volume fraction. The analysis of thermal conductivity based on the model Cheng and Vachon, model Lewis and Nielsen where this model has the function to support experiment finding. It is proved that Lewis' and Nielsen's model almost approach experiment result. And then thermal conductivity raising will be analyzed by the model of pararel-series conductive with the two (2)phases system. It is showed that sand in PP MF 2 composite have the big role to increase the thermal conductivity than sand in PP MF 10 composition, but it is not easy to shape conductive medium

[From manual workshop to international standard maker: exploration on production standard of acupuncture needle by Chengjiang acupuncture school].

Science.gov (United States)

Cheng, Jie; Cao, Yang; Xia, Youbing

2015-02-01

ABSTRACT The exploration course on production standard of acupuncture needle by Chengjiang acupuncture school is reviewed in this paper. After new China was established, acupuncture needle standard was unified by Mr. CHENG Dan-an, which guided Suzhou Hua Erfang (predecessor of Suzhou Medical Supplies Factory) to make the quality standards and testing methods of acupuncture needle and improved the production process to make the modern acupuncture needle. Based on this, Suzhou Medical Supplies Factory followed the time development pace, ac tively introduced new technology, carried out technological innovation, and constantly improved the level of production technology, as a result, it gradually developed into one of the world's largest acupuncture needle production suppliers. Meanwhile, after establishing China's first national standard on acupuncture needle (GB 2024-1980), the Suzhou Medical Supplies Factory took the lead to draft "ISO) 17218:2014 the disposable use asepsis acupuncture needle", which was officially published as an international standard. The Suzhou Medical Supplies Factory developed from a manual workshop to an international standard maker.

Recent development in clusters of rare earths and actinides. Chemistry and materials

International Nuclear Information System (INIS)

Zheng, Zhiping

2017-01-01

This book contains the following eight contributions: 1. Lanthanide Hydroxide Cluster Complexes via Ligand-Controlled Hydrolysis of the Lanthanide Ions (Zhonghao Zhang, Yanan Zhang, and Zhiping Zheng); 2. Synthesis and Structures of Lanthanide-Transition Metal Clusters (Xiu-Ying Zheng, Xiang-Jian Kong, and La-Sheng Long); 3. Hydrothermal Synthesis of Lanthanide and Lanthanide-Transition-Metal Cluster Organic Frameworks via Synergistic Coordination Strategy (Jian-Wen Cheng and Guo-Yu Yang); 4. Oxo Clusters of 5f Elements (Sarah Hickam and Peter C.); 5. Construction and Luminescence Properties of 4f and d-4f Clusters with Salen-Type Schiff Base Ligands (Xiaoping Yang, Shiqing Wang, Chengri Wang, Shaoming Huang, and Richard A.); 6. 4f-Clusters for Cryogenic Magnetic Cooling (Yan-Cong Chen, Jun-Liang Liu, and Ming-Liang Tong); 7. Lanthanide Clusters Toward Single-Molecule Magnets (Tian Han, You-Song Ding, and Yan-Zhen Zheng); 8. Molecular Rare Earth Hydride Clusters (Takanori Shima and Zhaomin Hou).

Depressive realism and the effect of intertrial interval on judgements of zero, positive, and negative contingencies.

Science.gov (United States)

Msetfi, Rachel M; Murphy, Robin A; Simpson, Jane

2007-03-01

In three experiments we tested how the spacing of trials during acquisition of zero, positive, and negative response-outcome contingencies differentially affected depressed and nondepressed students' judgements. Experiment 1 found that nondepressed participants' judgements of zero contingencies increased with longer intertrial intervals (ITIs) but not simply longer procedure durations. Depressed groups' judgements were not sensitive to either manipulation, producing an effect known as depressive realism only with long ITIs. Experiments 2 and 3 tested predictions of Cheng's (1997) Power PC theory and the Rescorla-Wagner (1972) model, that the increase in context exposure experienced during the ITI might influence judgements most with negative contingencies and least with positive contingencies. Results suggested that depressed people were less sensitive to differences in contingency and contextual exposure. We propose that a context-processing difference between depressed and nondepressed people removes any objective notion of "realism" that was originally employed to explain the depressive realism effect (Alloy & Abramson, 1979).

Empirical atom model of Vegard's law

Energy Technology Data Exchange (ETDEWEB)

Zhang, Lei, E-mail: zhleile2002@163.com [Materials Department, College of Electromechanical Engineering, China University of Petroleum, Qingdao 266555 (China); School of Electromechanical Automobile Engineering, Yantai University, Yantai 264005 (China); Li, Shichun [Materials Department, College of Electromechanical Engineering, China University of Petroleum, Qingdao 266555 (China)

2014-02-01

Vegard's law seldom holds true for most binary continuous solid solutions. When two components form a solid solution, the atom radii of component elements will change to satisfy the continuity requirement of electron density at the interface between component atom A and atom B so that the atom with larger electron density will expand and the atom with the smaller one will contract. If the expansion and contraction of the atomic radii of A and B respectively are equal in magnitude, Vegard's law will hold true. However, the expansion and contraction of two component atoms are not equal in most situations. The magnitude of the variation will depend on the cohesive energy of corresponding element crystals. An empirical atom model of Vegard's law has been proposed to account for signs of deviations according to the electron density at Wigner–Seitz cell from Thomas–Fermi–Dirac–Cheng model.

Investigation of Thermal Properties of High-Density Polyethylene/Aluminum Nanocomposites by Photothermal Infrared Radiometry

Science.gov (United States)

Koca, H. D.; Evgin, T.; Horny, N.; Chirtoc, M.; Turgut, A.; Tavman, I. H.

2017-12-01

In this study, thermal properties of high-density polyethylene (HDPE) filled with nanosized Al particles (80 nm) were investigated. Samples were prepared using melt mixing method up to filler volume fraction of 29 %, followed by compression molding. By using modulated photothermal radiometry (PTR) technique, thermal diffusivity and thermal effusivity were obtained. The effective thermal conductivity of nanocomposites was calculated directly from PTR measurements and from the measurements of density, specific heat capacity (by differential scanning calorimetry) and thermal diffusivity (obtained from PTR signal amplitude and phase). It is concluded that the thermal conductivity of HDPE composites increases with increasing Al fraction and the highest effective thermal conductivity enhancement of 205 % is achieved at a filler volume fraction of 29 %. The obtained results were compared with the theoretical models and experimental data given in the literature. The results demonstrate that Agari and Uno, and Cheng and Vachon models can predict well the thermal conductivity of HDPE/Al nanocomposites in the whole range of Al fractions.

Dextromethorphan attenuated inflammation and combined opioid use in humans undergoing methadone maintenance treatment.

Science.gov (United States)

Chen, Shiou-Lan; Lee, Sheng-Yu; Tao, Pao-Luh; Chang, Yun-Hsuan; Chen, Shih-Heng; Chu, Chun-Hsien; Chen, Po See; Lee, I Hui; Yeh, Tzung Lieh; Yang, Yen Kuang; Hong, Jau-Shyong; Lu, Ru-Band

2012-12-01

Recent studies show that proinflammatory cytokines might be related to the development of opioid dependence (physiological, psychological, or both). In a double-blind, randomly stratified clinical trial investigating whether add-on dextromethorphan (60-120 mg/day) attenuated inflammation and the combined use of opioids in heroin-dependent patients undergoing methadone maintenance treatment, we evaluated whether inflammation is related to the progression of opioid dependence. All participants (107 heroin-dependent patients and 84 nondependent healthy controls) were recruited from National Cheng Kung University Hospital. Their plasma cytokine levels were measured to evaluate the effect of add-on dextromethorphan. Plasma TNF-α and IL-8 levels were significantly higher in long-term heroin-dependent patients than in healthy controls (p dextromethorphan. Moreover, both tolerance to methadone and the combined use of opioids were significantly (p dextromethorphan. We conclude that dextromethorphan might be a feasible adjuvant therapeutic for attenuating inflammation and inhibiting methadone tolerance and combined opioid use in heroin-dependent patients.

Ion temperature effects on magnetotail Alfvén wave propagation and electron energization: ION TEMPERATURE EFFECTS ON ALFVÉN WAVES

Energy Technology Data Exchange (ETDEWEB)

Damiano, P. A. [Princeton Center for Heliophysics, Princeton Plasma Physics Laboratory, Princeton University, Princeton New Jersey USA; Johnson, J. R. [Princeton Center for Heliophysics, Princeton Plasma Physics Laboratory, Princeton University, Princeton New Jersey USA; Chaston, C. C. [Space Sciences Laboratory, University of California, Berkeley California USA; School of Physics, University of Sydney, Sydney New South Wales Australia

2015-07-01

A new 2-D self-consistent hybrid gyrofluid-kinetic electron model in dipolar coordinates is presented and used to simulate dispersive-scale Alfvén wave pulse propagation from the equator to the ionosphere along an L = 10 magnetic field line. The model is an extension of the hybrid MHD-kinetic electron model that incorporates ion Larmor radius corrections via the kinetic fluid model of Cheng and Johnson (1999). It is found that consideration of a realistic ion to electron temperature ratio decreases the propagation time of the wave from the plasma sheet to the ionosphere by several seconds relative to a ρi=0 case (which also implies shorter timing for a substorm onset signal) and leads to significant dispersion of wave energy perpendicular to the ambient magnetic field. Additionally, ion temperature effects reduce the parallel current and electron energization all along the field line for the same magnitude perpendicular electric field perturbation.

Study on the transformed strategy of “life field” for aged in coal mine community——A case sstudy of ccommunity rrenewal ddesign of Sihe coal mine in Jincheng, Shanxi

Science.gov (United States)

Xue, Minghui; Wang, Chenghao; Zhang, Shanshan

2017-06-01

Coal mine community is driven by the coal mine industry, and it mainly relies on coal mining enterprises to provide benefits for residents. Under the background of increasing serious global aging problem, the problems in the field of elderly people’s health, life, entertainment, communication, retirement and re-employment and other aspects become more acute and urgently to be solved. So it is necessary to make a more detailed study on how to transform the coal mine community according to the special needs of the elderly miners. This article takes renewal design of SiHe coal mine in JinCheng of ShanXi province as an example and takes the community’s “life field” as a clue, trying to put forward the transformed strategy of “life field” for aged in coal mine community and to come up with a method to update the community throughout the whole atmosphere to the personal space.

KALIMER-600-clad Core Fuel Assembly Calculation using MATRA-LMR (V2.0) Code

International Nuclear Information System (INIS)

Kim, Young Gyun; Kim, Young Il

2006-12-01

Since the sodium boiling point is very high, maximum cladding and pin temperatures are used for design limit condition in sodium cooled liquid metal reactor. It is necessary to predict accurately the temperature distribution in the core and in the subassemblies to increase the sodium coolant efficiency. Based on the MATRA code, which is developed for PWR analysis, MATRA-LMR has been developed for SFR. The major modifications are: the sodium properties table is implemented as subprogram in the code, Heat transfer coefficients are changed for SFR, te pressure drop correlations are changed for more accurate calculations, which are Novendstern, Chiu-Rohsenow-Todreas, and Cheng-Todreas correlations. This This report describes briefly code structure and equations of MATRA-LMR (Version 2.0), explains input data preparation and shows some calculation results for the KALIMER-600-clad core fuel assembly for which has been performed the conceptual design of the core in the year 2006

An online conserved SSR discovery through cross-species comparison

Directory of Open Access Journals (Sweden)

Tun-Wen Pai

2009-02-01

Full Text Available Tun-Wen Pai1, Chien-Ming Chen1, Meng-Chang Hsiao1, Ronshan Cheng2, Wen-Shyong Tzou3, Chin-Hua Hu31Department of Computer Science and Engineering; 2Department of Aquaculture, 3Institute of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung, Taiwan, Republic of ChinaAbstract: Simple sequence repeats (SSRs play important roles in gene regulation and genome evolution. Although there exist several online resources for SSR mining, most of them only extract general SSR patterns without providing functional information. Here, an online search tool, CG-SSR (Comparative Genomics SSR discovery, has been developed for discovering potential functional SSRs from vertebrate genomes through cross-species comparison. In addition to revealing SSR candidates in conserved regions among various species, it also combines accurate coordinate and functional genomics information. CG-SSR is the first comprehensive and efficient online tool for conserved SSR discovery.Keywords: microsatellites, genome, comparative genomics, functional SSR, gene ontology, conserved region

Clinical use of gadobutrol for contrast-enhanced magnetic resonance imaging of neurological diseases

Directory of Open Access Journals (Sweden)

Cheng KT

2012-02-01

Full Text Available Kenneth T Cheng1, Hannah Y Cheng2, Kam Leung31Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, USA; 2Freelance Technical Writer, New Orleans, LA, USA; 3National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USAAbstract: Contrast-enhanced magnetic resonance imaging (CE-MRI is an important clinical tool for diagnosing neurological diseases. The appropriate use of a suitable MRI contrast agent or contrast pharmaceutical is essential for CE-MRI to produce desirable diagnostic images. Currently, there are seven contrast agents (CAs or pharmaceuticals approved for clinical imaging of the central nervous system (CNS in the US, Europe, or Japan. All of the clinically approved CAs are water-soluble gadolinium-based contrast agents (GBCAs which do not penetrate the CNS blood–brain barrier (BBB. These agents are used for imaging CNS areas without a BBB, or various pathologies, such as tumors and infection that break down the BBB and allow CAs to enter into the surrounding parenchyma. Clinically, GBCAs are most useful for detecting primary and secondary cerebral neoplastic lesions. Among these CNS GBCAs, gadobutrol (Gd-BT-DO3A, Gadovist™ is a neutral, nonionic, macrocyclic compound that showed promising results from clinical trials of CNS imaging. In comparison with other GBCAs, Gd-BT-DO3A has relatively high in vitro kinetic stability and r1 relaxivity. Gd-BT-DO3A has been recently approved by the US Food and Drug Administration (FDA in 2011 for CNS imaging. A review of available literature shows that Gd-BT-DO3A exhibits similar safety and clinical efficacy profiles to other GBCAs. Gd-BT-DO3A has the distinguishing feature that it is the only clinical agent commercially available in a formulation of 1.0 M concentration with a relatively higher in vitro T1 shortening per unit volume than other clinical GBCAs which are only

Meta-analysis of the impact of de novo and acquired EGFR T790M mutations on the prognosis of patients with non-small cell lung cancer receiving EGFR-TKIs

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Liu Y

2017-04-01

Full Text Available Yang Liu, Li Sun, Zhi-Cheng Xiong, Xin Sun, Shu-Ling Zhang, Jie-Tao Ma, Cheng-Bo Han Department of Oncology, Shengjing Hospital of China Medical University, Shenyang, People’s Republic of China Purpose: The purpose of this meta-analysis was to explore the influences of pretreatment de novo and posttreatment-acquired epidermal growth factor receptor (EGFR T790M mutations in patients with advanced non-small cell lung cancer (NSCLC who had received tyrosine kinase inhibitors (TKIs.Methods: We searched PubMed, Embase, and the China National Knowledge Infrastructure database for eligible literature. Data were extracted to assess the hazard ratios (HRs for progression-free survival (PFS, overall survival (OS, and post-progression survival (PPS and the relative ratios (RRs for objective response rate (ORR.Results: This meta-analysis included 22 studies comprising 1,462 patients with NSCLC who harbored activating EGFR mutations and were treated with EGFR-TKIs. Compared to pretreatment T790M mutation-negative NSCLC, pretreatment T790M mutation-positive NSCLC was associated with decreased PFS (HR 2.23, P<0.001 and OS (HR 1.55, P=0.003. A trend toward significance of worsening ORR (RR 0.86, P=0.051 was evident. The acquired T790M mutation was correlated with improved PFS (HR 0.75, P=0.006 and PPS (HR 0.57, P<0.001, compared to patients without the T790M mutation who progressed after EGFR-TKI treatment. There were no significant differences in OS or ORR between patients with acquired T790M mutation-positive and T790M mutation-negative NSCLC. However, in the tumor tissue rebiopsy subgroup, patients with acquired T790M mutation had improved OS (HR 0.60, P<0.001 compared to T790M mutation-negative patients. In the plasma ctDNA subgroup, acquired T790M mutation decreased the OS (HR 1.87, P<0.001.Conclusion: Pretreatment T790M mutation was associated with worse PFS and OS in patients with advanced NSCLC treated with EGFR-TKIs, while acquired T790M mutation was

Further evidence that rats rely on local rather than global spatial information to locate a hidden goal: reply to Cheng and Gallistel (2005).

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McGregor, Anthony; Jones, Peter M; Good, Mark A; Pearce, John M

2006-07-01

Naive male Hooded Lister rats (Rattus norvegicus) were required to find a submerged platform in a right-angled corner between a long and a short wall of a pool in the shape of an irregular pentagon. Tests in a rectangular pool revealed a preference for the corners that corresponded with the correct corner in the pentagon. These findings indicate that rats identified the correct corner in the pentagon by local cues. They contradict the suggestion that rats navigate by moving in a particular direction relative to the principal axis of the shape of their environment.

the studyof the effect of varaiety seking and involvement in purchase intention on customers attitude ( customers satisfaction ,loyalty,intent toward,chenging the brand)

OpenAIRE

Azarnosh Ansari; Nasir Ketabi; Zeynab Saber; Hadi Teimoori

2015-01-01

This study aimed to investigate the relationship between customer’s satisfaction, loyalty and intention to switch family restaurant’s brand by considering the modifying impact of customer’s variety seeking and purchase decision involvement. With this regard, statistical population consisted of family restaurants customers in Isfahan, municipality 3, from which 380 people were considered using simple random sampling. This was an applicable research in terms of its purpose, and a descriptive-su...

Fractal analysis of the hydraulic conductivity on a sandy porous media reproduced in a laboratory facility.

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de Bartolo, S.; Fallico, C.; Straface, S.; Troisi, S.; Veltri, M.

2009-04-01

The complexity characterization of the porous media structure, in terms of the "pore" phase and the "solid" phase, can be carried out by means of the fractal geometry which is able to put in relationship the soil structural properties and the water content. It is particularly complicated to describe analytically the hydraulic conductivity for the irregularity of the porous media structure. However these can be described by many fractal models considering the soil structure as the distribution of particles dimensions, the distribution of the solid aggregates, the surface of the pore-solid interface and the fractal mass of the "pore" and "solid" phases. In this paper the fractal model of Yu and Cheng (2002) and Yu and Liu (2004), for a saturated bidispersed porous media, was considered. This model, using the Sierpinsky-type gasket scheme, doesn't contain empiric constants and furnishes a well accord with the experimental data. For this study an unconfined aquifer was reproduced by means of a tank with a volume of 10 Ã- 7 Ã- 3 m3, filled with a homogeneous sand (95% of SiO2), with a high percentage (86.4%) of grains between 0.063mm and 0.125mm and a medium-high permeability. From the hydraulic point of view, 17 boreholes, a pumping well and a drainage ring around its edge were placed. The permeability was measured utilizing three different methods, consisting respectively in pumping test, slug test and laboratory analysis of an undisturbed soil cores, each of that involving in the measurement a different support volume. The temporal series of the drawdown obtained by the pumping test were analyzed by the Neuman-type Curve method (1972), because the saturated part above the bottom of the facility represents an unconfined aquifer. The data analysis of the slug test were performed by the Bouwer & Rice (1976) method and the laboratory analysis were performed on undisturbed saturated soil samples utilizing a falling head permeameter. The obtained values either of the

Normative and descriptive accounts of the influence of power and contingency on causal judgement.

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Perales, José C; Shanks, David R

2003-08-01

The power PC theory (Cheng, 1997) is a normative account of causal inference, which predicts that causal judgements are based on the power p of a potential cause, where p is the cause-effect contingency normalized by the base rate of the effect. In three experiments we demonstrate that both cause-effect contingency and effect base-rate independently affect estimates in causal learning tasks. In Experiment 1, causal strength judgements were directly related to power p in a task in which the effect base-rate was manipulated across two positive and two negative contingency conditions. In Experiments 2 and 3 contingency manipulations affected causal estimates in several situations in which power p was held constant, contrary to the power PC theory's predictions. This latter effect cannot be explained by participants' conflation of reliability and causal strength, as Experiment 3 demonstrated independence of causal judgements and confidence. From a descriptive point of view, the data are compatible with Pearce's (1987) model, as well as with several other judgement rules, but not with the Rescorla-Wagner (Rescorla & Wagner, 1972) or power PC models.

Investigation of the relaxor behavior of sol gel processed lanthanum lead titanium ceramics

Energy Technology Data Exchange (ETDEWEB)

Limame, K. [Centre Régional des Metiers de l' Education et de la Formation (CRMEF) de Fès, Rue deKuwait, BP 49, Fès (Morocco); Laboratoire de Physique Théorique et Appliquée, (LPTA), FSDM, B.P. 1796, Fès-Atlas, Fès (Morocco); Sayouri, S., E-mail: ssayouri@gmail.com [Laboratoire de Physique Théorique et Appliquée, (LPTA), FSDM, B.P. 1796, Fès-Atlas, Fès (Morocco); Yahyaoui, M.M. [Laboratoire de Physique Théorique et Appliquée, (LPTA), FSDM, B.P. 1796, Fès-Atlas, Fès (Morocco); Housni, A. [Laboratoire de Physique Théorique et Appliquée, (LPTA), FSDM, B.P. 1796, Fès-Atlas, Fès (Morocco); Institut Supérieur des Professions Infirmières et Techniques de Santé (ISPITS), Fès (Morocco); Jaber, B. [Centre National pour la Recherche Scientifique et Technique (CNRST), Angle Avenue Allal El Fassi avenue des FAR, Quartie Hay Ryad, BP8027 Nation Unies, Rabat (Morocco)

2016-08-01

A series of La doped lead titanate samples, with composition Pb{sub 1−x}La{sub x}Ti{sub 1−x/4}O{sub 3} (PLTx), where x=0.00; 0.02; 0.04; 0.06; 0.07; 0.08; 0.10; 0.12; 0.14; 0.16; 0.18; 0.21 and 0.22 was prepared using the sol–gel process. Addition of La gives rise to the two well-known phenomena: diffuseness and relaxation around the ferro-to-paraelectric transition; the two parameters related to these phenomena, and which give a satisfactory interpretation of them, have been estimated using the Uchino's quadratic law. This diffuse phase transition (DPT) has been investigated with the help of the Landau–Devonshire cluster theory and the model of Cheng et al., to show that polar regions may be generated around the DPT and far from the temperature, T{sub m}, of the maximum of the dielectric permittivity, which have as a direct consequence a non vanishing polarization even if T>T{sub m}.

New possibility of traditional Chinese and Japanese medicine as treatment for behavioral and psychiatric symptoms in dementia

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Kung FC

2012-10-01

Full Text Available Fan-Chin Kung,1 Ryouhei Ishii,2 Hsing-Cheng Liu,3 Masatoshi Takeda21Yuli Hospital, DOH, Hualien, Taiwan; 2Department of Psychiatry, Osaka University Graduate School of Medicine, Osaka, Japan; 3Department of General Psychiatry, Taipei City Psychiatric Center, Taipei, TaiwanAbstract: Yokukansan, one of the Kampo prescriptions, is composed of seven herbaceous plants and was developed in China in the 16th century as a cure for restlessness and agitation in children. Yokukansan has also become a popular drug combination in Japan, especially for the behavioral and psychiatric symptoms of dementia (BPSD. Recent studies have shown that yokukansan might also be quite effective against BPSD occurring in association with other types of dementia, such as Alzheimer's disease, Lewy body disease, Parkinson's disease with dementia, frontotemporal dementia, and vascular dementia. Researchers have intensively investigated yokukansan, focusing on the pharmacological mechanisms against glutamate-mediated excitotoxicity. This traditional Chinese and Japanese medicine holds potential promise for improving BPSD in elderly patients suffering from dementia.Keywords: yokukansan, dementia, Alzheimer's disease, behavioral and psychological symptoms of dementia, Kampo, glutamate

Nanofluidic Transistor Circuits

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Chang, Hsueh-Chia; Cheng, Li-Jing; Yan, Yu; Slouka, Zdenek; Senapati, Satyajyoti

2012-02-01

Non-equilibrium ion/fluid transport physics across on-chip membranes/nanopores is used to construct rectifying, hysteretic, oscillatory, excitatory and inhibitory nanofluidic elements. Analogs to linear resistors, capacitors, inductors and constant-phase elements were reported earlier (Chang and Yossifon, BMF 2009). Nonlinear rectifier is designed by introducing intra-membrane conductivity gradient and by asymmetric external depletion with a reverse rectification (Yossifon and Chang, PRL, PRE, Europhys Lett 2009-2011). Gating phenomenon is introduced by functionalizing polyelectrolytes whose conformation is field/pH sensitive (Wang, Chang and Zhu, Macromolecules 2010). Surface ion depletion can drive Rubinstein's microvortex instability (Chang, Yossifon and Demekhin, Annual Rev of Fluid Mech, 2012) or Onsager-Wien's water dissociation phenomenon, leading to two distinct overlimiting I-V features. Bipolar membranes exhibit an S-hysteresis due to water dissociation (Cheng and Chang, BMF 2011). Coupling the hysteretic diode with some linear elements result in autonomous ion current oscillations, which undergo classical transitions to chaos. Our integrated nanofluidic circuits are used for molecular sensing, protein separation/concentration, electrospray etc.

Conductivity Profile Determination by Eddy Current for Shot Peened Superalloy Surfaces Toward Residual Stress Assessment

International Nuclear Information System (INIS)

Shen, Y.; Lo, C. C. H.; Frishman, A. M.; Lee, C.; Nakagawa, N.

2007-01-01

This paper describes an eddy current model-based method for inverting near-surface conductivity deviation profiles of surface treated materials from swept-high frequency eddy current (SHFEC) data. This work forms part of our current research directed towards the development of an electromagnetic nondestructive technique for assessing residual stress of shot-peened superalloy components. The inversion procedure is based on the use of a parameterized function to describe the near-surface conductivity as a function of depth for a shot-peened surface, and the laterally uniform multi-layer theory of Cheng, Dodd and Deeds to calculate the resulting coil impedance deviations. The convergence of the inversion procedure has been tested against synthesized eddy current data. As a demonstration, the conductivity deviation profiles of a series of Inconel 718 specimens, shot peened at various Almen intensities, have been obtained by inversion. Several consistency tests were conducted to examine the reliability of the inverted conductivity profiles. The results show that conductivity deviation profiles can be reliably determined from SHFEC data within the accuracy of the current measurement system

Research Advance on Metasequoia: Applications of New Technology

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Leng, Qin; Yang, Hong; Wang, Li

2010-10-01

The plant genus Metasequoia Miki, 1941 and its sole living relict species Metasequoia glyptostroboides Hu et Cheng, 1948 have been of special interest for both the public and scientists since 1941 when the genus was established. Due to its unique discovery history (fossils discovered earlier than the living species) and incomparable scientific value in the research of plant evolution and its relationship with environmental and climatic changes, Metasequoia becomes arguably the most comprehensively studied higher plant in both fossil and living forms. This paper summarized recent advance in Metasequoia research by reviewing the research history of Metasequoia and the scientific value of this genus, while paid special attention to the application of new methods and techniques in the research field of Metasequoia in the recent decades. The application of biogeochemical (organic geochemistry and stable isotope) analysis as well as the new and innovated methods of preparing large-sized cuticular membrane from leaves with originally thin and fragile cuticles further secure Metasequoia's super star status for the research of palaeoclimatic reconstruction.

Monitoring of Surface Subsidence of the Mining Area Based on Sbas

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Zhu, Y.; Zhou, S.; Zang, D.; Lu, T.

2018-05-01

This paper has collected 7 scenes of L band PALSAR sensor radar data of a mine in FengCheng city, jiangxi province, using the Small-baseline Subset (SBAS) method to invert the surface subsidence of the mine. Baselines of interference less than 800m has been chosen to constitute short baseline differential interference atlas, using pixels whose average coherent coefficient was larger than or equal to 0.3 as like high coherent point target, using singular value decomposition (SVD) method to calculate deformation phase sequence based on these high coherent points, and the accumulation of settlements of study area of different period had been obtained, so as to reflect the ground surface settlement evolution of the settlement of the area. The results of the study has showed that: SBAS technology has overcome coherent problem of the traditionality D-InSAR technique, continuous deformation field of surface mining in time dimension of time could been obtained, characteristics of ground surface settlement of mining subsidence in different period has been displayed, so to improve the accuracy and reliability of the monitoring results.

Aspartate Aminotransferase and Alanine Aminotransferase Detection on Paper-Based Analytical Devices with Inkjet Printer-Sprayed Reagents

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Hsiang-Li Wang

2016-01-01

Full Text Available General biochemistry detection on paper-based microanalytical devices (PADs uses pipette titration. However, such an approach is extremely time-consuming for large-scale detection processes. Furthermore, while automated methods are available for increasing the efficiency of large-scale PAD production, the related equipment is very expensive. Accordingly, this study proposes a low-cost method for PAD manufacture, in which the reagent is applied using a modified inkjet printer. The optimal reaction times for the detection of aspartate aminotransferase (AST and alanine aminotransferase (ALT are shown to be 6 and 7 min, respectively, given AST and ALT concentrations in the range of 5.4 to 91.2 U/L (R2 = 0.9932 and 5.38 to 86.1 U/L (R2 = 0.9944. The experimental results obtained using the proposed PADs for the concentration detection of AST and ALT in real human blood serum samples are found to be in good agreement with those obtained using a traditional spectrophotometric detection method by National Cheng Kung University hospital.

Efficient implementation of one- and two-component analytical energy gradients in exact two-component theory

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Franzke, Yannick J.; Middendorf, Nils; Weigend, Florian

2018-03-01

We present an efficient algorithm for one- and two-component analytical energy gradients with respect to nuclear displacements in the exact two-component decoupling approach to the one-electron Dirac equation (X2C). Our approach is a generalization of the spin-free ansatz by Cheng and Gauss [J. Chem. Phys. 135, 084114 (2011)], where the perturbed one-electron Hamiltonian is calculated by solving a first-order response equation. Computational costs are drastically reduced by applying the diagonal local approximation to the unitary decoupling transformation (DLU) [D. Peng and M. Reiher, J. Chem. Phys. 136, 244108 (2012)] to the X2C Hamiltonian. The introduced error is found to be almost negligible as the mean absolute error of the optimized structures amounts to only 0.01 pm. Our implementation in TURBOMOLE is also available within the finite nucleus model based on a Gaussian charge distribution. For a X2C/DLU gradient calculation, computational effort scales cubically with the molecular size, while storage increases quadratically. The efficiency is demonstrated in calculations of large silver clusters and organometallic iridium complexes.

Ocular leech infestation

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Lee YC

2015-02-01

Full Text Available Yueh-Chang Lee, Cheng-Jen Chiu Department of Ophthalmology, Buddhist Tzu-Chi General Hospital, Hualien, Taiwan, ROC Abstract: This case report describes a female toddler with manifestations of ocular leech infestation. A 2-year-old girl was brought to our outpatient clinic with a complaint of irritable crying after being taken to a stream in Hualien 1 day previous, where she played in the water. The parents noticed that she rubbed her right eye a lot. Upon examination, the girl had good fix and follow in either eye. Slit-lamp examination showed conjunctival injection with a moving dark black–brown foreign body partly attached in the lower conjunctiva. After applying topical anesthetics, the leech, measuring 1 cm in length, was extracted under a microscope. The patient began using topical antibiotic and corticosteroid agents. By 1 week after extraction, the patient had no obvious symptoms or signs, except for a limited subconjunctival hemorrhage, and no corneal/scleral involvement was observed. Keywords: leech, ocular foreign body, conjunctival reaction, pediatric ophthalmology

Study on monitoring of deep foundation pit with SMW engineering method plus anchor cable retaining structure

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Chen, Wenzhao; Cui, Wenping

2018-03-01

The SMW method has many advantages, such as little influence on the surrounding environment, good watertight performance, wide range of application, short construction period, low cost and so on. In this paper, we chose the SMW engineering method combined with anchor cable to support structure in the second phase deep foundation pit of Jinan LuJinDongCheng as the research object, monitored and analysed the horizontal displacement of the pile top, Peripheral surface subsidence and internal force of the anchor cable in the foundation pit. We also discussed the displacement, internal force of anchor cable and the settlement of surrounding environment in the excavation of foundation pit and in different stages of construction. Conclusion:(1)The maximum horizontal displacement of the retaining structure is closely related to the depth and time of excavation, the construction of anchor cable can well limit the deformation of pile body; (2)Groundwater seepage caused by foundation pit dewatering will change the effective stress of soil. The change of groundwater level has an important influence on the working behavior of smw anchor cable supporting structure.

Treatment of severe fluoroacetamide poisoning in patient with combined multiple organ dysfunction syndrome by evidence-based integrated Chinese and Western medicines: A case report.

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Wen, Wanxin; Gao, Hongxia; Kang, Nini; Lu, Aili; Qian, Caiwen; Zhao, Yuanqi

2017-07-01

Fluoroacetamide poisoning is the acute and severe disease of human, which leads to nervous, digestive, and cardiovascular system damage or even death in a short period of time. We report a case of a 65-year-old woman with loss of consciousness, nausea, and vomiting who was sent to the hospital by passers-by. She was diagnosed with severe fluoroacetamide poisoning with combined multiple organ dysfunction syndrome. When the diagnosis was unclear, we gave gastric lavage, support and symptomatic treatment, and closely with the vital sign. When the diagnosis was clear, based on the evidence of retrieved, muscle injection of acetamide, calcium gluconate, and vitamin C. Traditional Chinese medicine aspect, oral administration of mung bean soup of glycyrrhizae and Da-Cheng-Qi decoction enema. By setting reasonable treatment for patients, she had no special discomfort and complications after treatment. Besides, through 1-month follow-up, it was confirmed that the treatments were effective. Evidence-based integrated Chinese and Western medicines can effectively improve the therapeutic effects in severe fluoroacetamide-poisoned patients with combined MODS.

La Actio Popularis en el Derecho Internacional Contemporáneo

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Marcus Vinicius Xavier de Oliveira

2018-04-01

Full Text Available Este trabajo objetivó enfrentar el problema relacionado a la vigencia, validez y eficacia del instituto de la actio popularis en el derecho internacional contemporáneo, teniendo como punto de intersección, por un lado, las decisiones dictadas por la Corte Internacional de Justicia en los casos Etiopía y Liberia v. África del Sur en los años 1962 y 1966, así como las críticas en relación a la vuelta radical que la Corte promovió entre los juicios de las Cuestiones Preliminares y la segunda fase, teniendo como sustrato teórico la crítica hecha por Egon Schwelb. Para ello, después de establecer las bases de la discusión en el tema relativo a la transición del sistema westfaliano al de la Carta, se discutía sobre el origen del instituto en el derecho romano, teniendo como principal apoyo la obra de Theodor Mommsen. El acto seguido se pasó a la presentación y discusión de las decisiones de la Corte Internacional de Justicia en el caso indicado, para señalar, en líneas posteriores, las críticas que dicha decisión sufrió. En el último tópico se discutió la correlación entre el instituto de la actio popularis con la máxima aut dedere aut judicare, en especial en el régimen indirecto de implementación del Derecho Penal Internacional. Se concluye el trabajo con consideraciones a confirmar la vigencia, validez y condiciones de eficacia y legitimidad de la justicia cosmopolita, cuya fundamentación se encuentra en la actio popularis. El método de abordaje adoptado en el presente trabajo fue el crítico, y el de procedimiento la consulta bibliográfica.

Comparative effects of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers on the risk of pneumonia and severe exacerbations in patients with COPD

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Lai CC

2018-03-01

Full Text Available Chih-Cheng Lai,1 Ya-Hui Wang,2 Cheng-Yi Wang,3 Hao-Chien Wang,4 Chong-Jen Yu,4 Likwang Chen5 On behalf of the Taiwan Clinical Trial Consortium for Respiratory Diseases (TCORE 1Department of Intensive Care Medicine, Chi Mei Medical Center, Liouying, Taiwan; 2Medical Research Center, Cardinal Tien Hospital and School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan; 3Department of Internal Medicine, Cardinal Tien Hospital and School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan; 4Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan; 5Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan Objectives: This study aimed to compare the effects of angiotensin-converting-enzyme inhibitors (ACEis and angiotensin receptor blockers (ARBs on the risk of pneumonia and severe exacerbations in patients with COPD.Patients and methods: All patients with COPD who used ACEis and ARBs for >90 days between 2000 and 2005 were recruited. Pairwise matching (1:1 of the ACEi and ARB groups resulted in two similar subgroups, with 6,226 patients in each. The primary outcomes were pneumonia and COPD exacerbations, and the secondary outcome was death.Results: During the follow-up period, the incidence of pneumonia was 7.20 per 100 person-years in the ACEi group and 5.89 per 100 person-years in the ARB group. The ACEi group had a higher risk of pneumonia (adjusted hazard ratio [aHR], 1.22; 95% CI, 1.15–1.29 than the ARB group. The incidence of severe exacerbations was 0.65 per person-year for the patients receiving ACEis and 0.52 per person-year for those receiving ARBs. The patients receiving ACEis had a higher risk of severe exacerbations (aHR, 1.19; 95% CI, 1.16–1.21 than those receiving ARBs. Similar trends were noted in terms of severe exacerbations requiring

Artificial Intelligence Learning Semantics via External Resources for Classifying Diagnosis Codes in Discharge Notes.

Science.gov (United States)

Lin, Chin; Hsu, Chia-Jung; Lou, Yu-Sheng; Yeh, Shih-Jen; Lee, Chia-Cheng; Su, Sui-Lung; Chen, Hsiang-Cheng

2017-11-06

extracted enough concepts to predict the diagnosis codes. Word embedding combined with a CNN showed outstanding performance compared with traditional methods, needing very little data preprocessing. This shows that future studies will not be limited by incomplete dictionaries. A large amount of unstructured information from free-text medical writing will be extracted by automated approaches in the future, and we believe that the health care field is about to enter the age of big data. ©Chin Lin, Chia-Jung Hsu, Yu-Sheng Lou, Shih-Jen Yeh, Chia-Cheng Lee, Sui-Lung Su, Hsiang-Cheng Chen. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 06.11.2017.

Development of betulinic acid as an agonist of TGR5 receptor using a new in vitro assay

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Lo SH

2016-08-01

Full Text Available Shih-Hsiang Lo,1,2 Kai-Chung Cheng,3 Ying-Xiao Li,3,4 Chin-Hong Chang,4,5 Juei-Tang Cheng,4,6 Kung-Shing Lee7,8 1Division of Cardiology, Department of Internal Medicine, Zhongxing Branch of Taipei City Hospital, 2Department of History and Geography, University of Taipei, Taipei, Taiwan; 3Department of Psychosomatic Internal Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan; 4Department of Medical Research, 5Department of Neurosurgery, Chi-Mei Medical Center, Yong Kang, 6Institute of Medical Science, College of Health Science, Chang Jung Christian University, Tainan, 7Department of Surgery, Pingtung Hospital, 8Division of Neurosurgery, Department of Surgery, Kaohsiung Medical University Chung-Ho Memorial Hospital, School of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan Background: G-protein-coupled bile acid receptor 1, also known as TGR5 is known to be involved in glucose homeostasis. In animal models, treatment with a TGR5 agonist induces incretin secretion to reduce hyperglycemia. Betulinic acid, a triterpenoid present in the leaves of white birch, has been introduced as a selective TGR5 agonist. However, direct activation of TGR5 by betulinic acid has not yet been reported. Methods: Transfection of TGR5 into cultured Chinese hamster ovary (CHO-K1 cells was performed to establish the presence of TGR5. Additionally, TGR5-specific small interfering RNA was employed to silence TGR5 in cells (NCI-H716 cells that secreted incretins. Uptake of glucose by CHO-K1 cells was evaluated using a fluorescent indicator. Amounts of cyclic adenosine monophosphate and glucagon-like peptide were quantified using enzyme-linked immunosorbent assay kits. Results: Betulinic acid dose-dependently increases glucose uptake by CHO-K1 cells transfected with TGR5 only, which can be considered an alternative method instead of radioligand binding assay. Additionally, signals coupled to TGR5 activation are also

Association of low serum aluminum level with mortality in hemodialysis patients

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Hsu CW

2016-09-01

Full Text Available Ching-Wei Hsu,1–3 Cheng-Hao Weng,1–3 Cheng-Chia Lee,1–3 Dan-Tzu Lin-Tan,1–3 Kuan-Hsing Chen,1–3 Tzung-Hai Yen,1–3 Wen-Hung Huang1–3 1Department of Nephrology, Division of Clinical Toxicology, Chang Gung Memorial Hospital, Taipei, Taiwan, Republic of China; 2Department of Nephrology, Division of Clinical Toxicology, Linkou Medical Center, Taoyuan, Taiwan, Republic of China; 3Department of Medicine, Chang Gung University College of Medicine, Taoyuan, Taiwan, Republic of China Background: The National Kidney Foundation–Kidney Disease Outcomes Quality Initiative recommends that the serum aluminum level (SAL should be below 20 µg/L for patients with maintenance hemodialysis (MHD. However, serum aluminum may have toxic effects on MHD patients even when it is in the apparently acceptable range (below 20 µg/L.Methods: The Medical Ethics Committee approved this study. Initially, 954 MHD patients in dialysis centers were recruited. A total of 901 patients met the inclusion criteria and were followed-up for 1 year. Patients were stratified by SAL into four equal-sized groups: first quartile (<6 µg/L, second quartile (6–9 µg/L, third quartile (9–13 µg/L, and fourth quartile (>13 µg/L. Demographic, biochemical, and dialysis-related data were obtained for analyses. A linear regression model was applied to identify factors associated with SAL. Cox proportional hazard model was used to determine the significance of variables in prediction of mortality.Results: Only 9.3% of MHD patients had SALs of 20 µg/L or more. At the end of the follow-up, 54 patients (6% died, and the main cause of death was cardiovascular disease. Kaplan–Meier survival analysis showed that patients in the fourth SAL quartile had higher mortality than those in the first SAL quartile (log rank test, χ2=13.47, P=0.004. Using the first quartile as reference, Cox multivariate analysis indicated that patients in the third quartile (hazard ratio =1.31, 95% confidence

Assessment of pain score and specimen adequacy for ultrasound-guided fine-needle aspiration biopsy of thyroid nodules

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Liao LJ

2017-12-01

Full Text Available Li-Jen Liao,1 Wu-Chia Lo,1 Wan-Lun Hsu,2 Po-Wen Cheng,1 Cheng-Ping Wang3 1Department of Otolaryngology, Far Eastern Memorial Hospital, 2Genomics Research Center, Academia Sinica, 3Department of Otolaryngology, National Taiwan University Hospital, Taipei, Taiwan, Republic of China Objective: The aim of this study was to evaluate pain scores and specimen adequacy for ultrasound-guided fine-needle aspiration biopsy (US-FNAB of thyroid nodules without and with local anesthesia (LA. Materials and methods: The US-FNAB procedure was performed on 183 patients with and without LA. One puncture was made for solid nodules, and if patients could tolerate it, a two-puncture technique was used for nodules with a cystic change. Four-point verbal rating scores were assessed by a nursing assistant after completion of US-FNAB. To be an adequate specimen, at least six groups of follicular cells are required, and each group should contain at least 10 cells.Results: Immediately after US-FNAB, 92% of patients with LA and 80% without LA reported no or mild pain (p=0.01. Most patients tolerated the procedure well, with no pain (82.5% reported 5 minutes after the procedure. In univariate logistic regression, irregular boundary (odds ratio [OR]: 2.52, 95% confidence interval [CI]: 1.04–6.06, p=0.04, calcification (OR: 2.86, 95% CI: 1.06–7.76, p=0.04, and LA (OR: 0.35, 95% CI: 0.15–0.86, p=0.02 were significantly associated with immediate moderate or severe pain. Specimen adequacy was significantly associated with age (OR: 0.95, 95% CI: 0.92–0.97, p<0.01, heterogeneous echo-texture (OR: 1.76, 95% CI: 1.23–5.17, p=0.01, predominate solid architecture (OR: 2.78, 95% CI: 1.42–5.41, p<0.01, and the use of LA (OR: 3.34, 95% CI: 1.70–6.56, p<0.01. In multivariate logistic regression, patients receiving LA had lower risk of moderate or severe pain (OR: 0.25, 95% CI: 0.09–0.67, p=0.01 and higher chances of specimen adequacy (OR: 4.84, 95% CI: 2.17–10.7, p<0

Potential role of pre- and postnatal testosterone levels in attention-deficit/hyperactivity disorder: is there a sex difference?

Directory of Open Access Journals (Sweden)

Wang LJ

2017-05-01

Full Text Available Liang-Jen Wang,1,2 Miao-Chun Chou,1 Wen-Jiun Chou,1 Min-Jing Lee,1 Sheng-Yu Lee,3,4 Pao-Yen Lin,5 Yi-Hsuan Lee,1 Yi-Hsin Yang,6 Cheng-Fang Yen2,7 1Department of Child and Adolescent Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, 2Department of Psychiatry, School of Medicine, and Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, 3Department of Psychiatry, Kaohsiung Veterans General Hospital, Kaohsiung, 4Department of Psychiatry, College of Medicine and Hospital, National Cheng Kung University, Tainan, 5Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, 6School of Pharmacy, Kaohsiung Medical University Hospital, 7Department of Psychiatry, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan Objective: Both prenatal testosterone (T exposure and postnatal T levels have been associated with developing neural circuitry and behavioral systems. This study examined the potential correlation between pre- and postnatal T levels and behavioral and neurocognitive profiles of children with attention-deficit/hyperactivity disorder (ADHD.Methods: Two hundred ADHD patients with a mean age of 8.7±2.0 years (158 boys and 42 girls were recruited. The ratio of the length of the right index finger (2D to that of the right ring finger (4D (2D/4D ratio served as a surrogate of prenatal T exposure, and postnatal T was determined using salivary T concentration. Behavioral symptoms were evaluated using the Swanson, Nolan, and Pelham – Version IV Scale for ADHD (SNAP-IV. Neurocognitive function was assessed using the Wechsler Intelligence Scale for Children – Fourth Edition (WISC-IV and Conners’ Continuous Performance Test (CPT.Results: Lower 2D/4D ratios were associated with comorbid disruptive behavior disorders (t=2.15, P=0.033 in all participants. Among the boys with ADHD, neither 2D/4D ratios nor salivary T levels

Trend, characteristics, and pharmacotherapy of adults diagnosed with attention-deficit/hyperactivity disorder: a nationwide survey in Taiwan

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Cheng YS

2017-03-01

Full Text Available Yu-Shian Cheng,1,2 Yu-Chiau Shyu,3,4 Sheng-Yu Lee,5,6 Shin-Sheng Yuan,7 Chun-Ju Yang,8 Kang-Chung Yang,8,9 Tung-Liang Lee,10 Liang-Jen Wang1 1Department of Child and Adolescent Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, 2Department of Psychiatry, Tsyr-Huey Mental Hospital, Kaohsiung Jen-Ai’s Home, Kaohsiung, 3Community Medicine Research Center, Keelung Chang Gung Memorial Hospital, Keelung, 4Institute of Molecular Biology, Academia Sinica, Nankang, Taipei, 5Department of Psychiatry, Kaohsiung Veterans General Hospital, Kaohsiung, 6Department of Psychiatry, College of Medicine and Hospital, National Cheng Kung University, Tainan, 7Institute of Statistical Science, Academia Sinica, 8Institute of Biopharmaceutical Sciences, National Yang-Ming University, 9Genome and Systems Biology Degree Program, National Taiwan University, Taipei, Taiwan; 10Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA Objective: Attention-deficit/hyperactivity disorder (ADHD in adults may result in functional impairment warranting clinical interventions. However, few studies have investigated the diagnosis and treatment rates of adult ADHD in non-Caucasian ethnic groups. This study used nationwide population-based data to investigate the rate of diagnosis, associated characteristics, and pharmacological treatment for adult ADHD in Taiwan. Methods: Adults (age ≥18 years newly diagnosed with ADHD (n=5,397 between January 2000 and December 2011 were enrolled from the National Health Insurance database in Taiwan. All patients were monitored until December 31, 2011. Patients who received treatment with immediate-release methylphenidate (IR-MPH, osmotic release oral system-methylphenidate (OROS-MPH, and atomoxetine (ATX were analyzed. Results: The cumulative prevalence of adult ADHD was 0.028%, and the incidence increased 10.9-fold from 2000 to 2011. The male to female ratio

Growing with dinosaurs: natural products from the Cretaceous relict Metasequoia glyptostroboides Hu & Cheng?a molecular reservoir from the ancient world with potential in modern medicine

OpenAIRE

Juvik, Ole Johan; Nguyen, Xuan Hong Thy; Andersen, Heidi Lie; Fossen, Torgils

2015-01-01

After the sensational rediscovery of living exemplars of the Cretaceous relict Metasequoia glyptostroboides—a tree previously known exclusively from fossils from various locations in the northern hemisphere, there has been an increasing interest in discovery of novel natural products from this unique plant source. This article includes the first complete compilation of natural products reported from M. glyptostroboides during the entire period in which the tree has been investigated (1954–201...

Growing with dinosaurs: natural products from the Cretaceous relict Metasequoia glyptostroboides Hu & Cheng-a molecular reservoir from the ancient world with potential in modern medicine.

Science.gov (United States)

Juvik, Ole Johan; Nguyen, Xuan Hong Thy; Andersen, Heidi Lie; Fossen, Torgils

2016-01-01

After the sensational rediscovery of living exemplars of the Cretaceous relict Metasequoia glyptostroboides -a tree previously known exclusively from fossils from various locations in the northern hemisphere, there has been an increasing interest in discovery of novel natural products from this unique plant source. This article includes the first complete compilation of natural products reported from M. glyptostroboides during the entire period in which the tree has been investigated (1954-2014) with main focus on the compounds specific to this plant source. Studies on the biological activity of pure compounds and extracts derived from M. glyptostroboides are reviewed for the first time. The unique potential of M. glyptostroboides as a source of bioactive constituents is founded on the fact that the tree seems to have survived unchanged since the Cretaceous era. Since then, its molecular defense system has resisted the attacks of millions of generations of pathogens. In line with this, some recent landmarks in Metasequoia paleobotany are covered. Initial spectral analysis of recently discovered intact 53 million year old wood and amber of Metasequoia strongly indicate that the tree has remained unchanged for millions of years at the molecular level.

Study guide for Statistics for business and financial economics a supplement to the textbook by Cheng-Few Lee, John C. Lee and Alice C. Lee

CERN Document Server

Moy, Ronald L; Kao, Lie Jane

2015-01-01

This Study Guide accompanies Statistics for Business and Financial Economics, 3rd Ed. (Springer, 2013), which is a business statistics textbook that uses finance, economics, and accounting data throughout the book. This Study Guide contains unique chapter reviews for each chapter in the textbook, formulas, examples, and additional exercises to enhance topics and their application. Solutions are included so students can evaluate their own understanding of the material. With more real-life data sets than the other books on the market, this study guide and the textbook that it accompanies, give readers all the tools they need to learn material in class and on their own. The topics covered are immediately applicable to facing uncertainty and the science of good decision making in financial analysis, econometrics, auditing, production, operations, and marketing research. Students in business degree programs will find this material particularly useful in their other courses and future work.

Effects of habitat disturbance on the pollination system of Ammopiptanthus mongolicus (Maxim) Cheng f. at the landscape-level in an arid region of Northwest China.

Science.gov (United States)

Chen, Min; Zhao, Xue-Yong; Zuo, Xiao-An; Mao, Wei; Qu, Hao; Zhu, Yang-Chun

2016-05-01

Ammopiptanthus mongolicus is an ecologically important species in the arid region of Northwest China. Habitat disturbance can significantly affect plant mating success and ultimately species viability. Pollen limitation of plant reproduction occurs in many plant species, particularly those under habitat disturbance. However, previous investigations have demonstrated differences in pollen limitation between conserved and disturbed sites. We compared the phenology, pollen limitation, pollinators and breeding system of both sites to determine whether habitat disturbance has generated changes in these plant components. We found that the species differed in four aspects. First, blooming duration and flowering peak were longer in the disturbed site than in the conserved site. Second, A. mongolicus can be pollen-limited and pollen limitation was more intense in the conserved site than in the disturbed site. Third, Anthophora uljanini was found to be a frequent pollinator in the conserved site, while Apis mellifera was the most effective and frequent flower visitor. More pollinator visits were recorded in the disturbed site, which could explain the differences in reproductive success. Finally, seed set was higher in the disturbed site than in the conserved site. We found that outcrossing was dominant in both sites and that agamospermy and self-pollination played complementary roles to ensure reproduction. Differences in flower production influenced by artificial selection and pollinator type explain the different seed set in both sites, whereas habitat disturbance cause changes differences in the pollination process and limits pollen flow. The balance between artificial management and mating success is crucial to analysis of the pollination process and manipulation of A. mongolicus population size.

Oral traditional Chinese medication for adhesive small bowel obstruction.

Science.gov (United States)

Suo, Tao; Gu, Xixi; Andersson, Roland; Ma, Huaixing; Zhang, Wei; Deng, Wei; Zhang, Boheng; Cai, Dingfang; Qin, Xinyu

2012-05-16

); continuous outcomes are presented as mean differences (MD) and 95% CIs. The data analyses were carried out using Review Manager 5.1. For cases in which necessary information was not reported in the paper, we contacted the primary authors for additional information. Five randomised trials involving 664 participants were analysed. Five different herbal medicines were tested in these trials, including Huo-Xue-Tong-Fu decoction, Xiao-Cheng-Qi-Tang decoction, a combination of Xiao-Cheng-Qi-Tang and Si-Jun-Zi-Tang decoctions, Chang-Nian-Lian-Song-Jie-Tang decoction, and Fufang-Da-Cheng-Qi-Tang decoction. There were variations in the tested herbal compositions and methods of medicine administration. The main outcomes reported in the trials were effects on abdominal pain, abdominal distension, constipation defection, time of first defecation after treatment, and reoperation rate during the course of the disease. Secondary outcomes selected for this review were not available, including complications such as small bowel perfusion (bowel resection, system complications, and other possible complications), length of hospital stay, cost of hospitalisation, and time from admission to surgical intervention. The results of five trials showed that patients receiving TCM combined with conventional therapy seemed to have improved outcomes compared with patients receiving conventional treatment alone (OR 4.24, 95% CI 2.83 to 6.36).However, we cannot conclusively determine the efficacy of TCM in this review due to inadequate reporting, low methodological quality, and the prevalence of various biases in the reviewed studies. Furthermore, because none of the reviewed trials discussed adverse events, we could not evaluate the safety of TCM for adhesive SBO patients. All trials were conducted and published in China. Although many studies have assessed the use of TCM products for adhesive SBO, most were excluded from this review due to their methodological limitations. This systematic review did not

Great auricular neuropraxia with beach chair position

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Joshi M

2017-07-01

Full Text Available Minal Joshi,1 Ruth Cheng,2 Hattiyangadi Kamath,1 Joel Yarmush1 1Department of Anesthesiology, New York Methodist Hospital, New York, NY, USA; 2School of Medicine, St. George’s University, Grenada, West Indies Abstract: Shoulder arthroscopy has been shown to be the procedure of choice for many diagnostic and therapeutic interventions. Neuropraxia of the great auricular nerve (GAN is an uncommon complication of shoulder surgery, with the patient in the beach chair position. We report a case of great auricular neuropraxia associated with direct compression by a horseshoe headrest, used in routine positioning for uncomplicated shoulder surgery. In this case, an arthroscopic approach was taken, under regional anesthesia with sedation in the beach chair position. The GAN, a superficial branch of the cervical plexus, is vulnerable to neuropraxia due to its superficial anatomical location. We recommend that for the procedures of the beach chair position, the auricle be protected and covered with cotton and gauze to avoid direct compression and the position of the head and neck be checked and corrected frequently. Keywords: neuropraxia, anesthesia, arthroscopy, great auricular nerve

pH and Protein Sensing with Functionalized Semiconducting Oxide Nanobelt FETs

Science.gov (United States)

Cheng, Yi; Yun, C. S.; Strouse, G. F.; Xiong, P.; Yang, R. S.; Wang, Z. L.

2008-03-01

We report solution pH sensing and selective protein detection with high-performance channel-limited field-effect transistors (FETs) based on single semiconducting oxide (ZnO and SnO2) nanobelts^1. The devices were integrated with PDMS microfluidic channels for analyte delivery and the source/drain contacts were passivated for in-solution sensing. pH sensing experiments were performed on FETs with functionalized and unmodified nanobelts. Functionalization of the nanobelts by APTES was found to greatly improve the pH sensitivity. The change in nanobelt conductance as functions of pH values at different gate voltages and ionic strengths showed high sensitivity and consistency. For the protein detection, we achieved highly selective biotinylation of the nanobelt channel with through APTES linkage. The specific binding of fluorescently-tagged streptavidin to the biotinylated nanobelt was verified by fluorescence microscopy; non-specific binding to the substrate was largely eliminated using PEG-silane passivation. The electrical responses of the biotinylated FETs to the streptavidin binding in PBS buffers of different pH values were systematically measured. The results will be presented and discussed. ^1Y. Cheng et al., Appl. Phys. Lett. 89, 093114 (2006). *Supported by NSF NIRT Grant ECS-0210332.

Transport properties of electron swarms in gaseous neon at low values of E/N

International Nuclear Information System (INIS)

Boyle, G J; Casey, M J E; White, R D; Cheng, Y; Mitroy, J

2014-01-01

A detailed analysis of electron swarm transport through neon gas at applied reduced electric fields of E/N < 2 Td is presented. The root mean square difference of transport parameters calculated from a recent all-order many-body perturbation theory treatment (Cheng et al 2014 Phys. Rev. A 89 012701) with drift velocity measurements by the Australian National University group (Robertson 1972 J. Phys. B 5 648) is less than 1%. Differences of about 3% exist with characteristic energies, D T /μ, (Koizumi et al 1984 J. Phys. B 17 4387) indicating an incompatibility at the 3% level between drift velocity and transverse diffusion coefficient measurements. Multi-term solutions of the Boltzmann equation indicate that the two-term approximation gives transport parameters accurate to better than 0.01%. The diffusion constant at thermal energies is found to be sensitive to the numerical representation of the cross section. A recommended elastic momentum transfer cross section has been constructed that has a maximum difference of 0.5% with all ANU drift velocity data for E/N < 1.6 Td and a root mean square difference that is about a factor of 2 smaller. (paper)

Activities of some enzymes of lignin formation in reaction wood of Thuja orientalis, Metasequoia glyptostroboides and Robinia pseudoacacia.

Science.gov (United States)

Kutsuki, H; Higuchi, T

1981-07-01

The activities of the following five enzymes which are involved in the formation of lignin have been compared in reaction wood and in opposite wood: phenylalanine ammonia lyase (EC 4.3.1.5), caffeate 3-O-methyltransferase (EC 2.1.1.-), p-hydroxycinnamate: CoA ligase (EC 6.2.1.12), cinnamyl alcohol dehydrogenase (EC 1.1.1.-) and peroxidase (EC 1.11.1.7). The activities of the four first-named enzymes in the compression wood of Thuja orientalis L. and Metasequoia glyptostroboides Hu et Cheng were 2.8±1.4-fold and 2.6±1.5-fold higher than those in opposite wood, respectively, whereas peroxidase had the same level of activity in either type of wood. On the other hand, no differences were observed in the activities of the five enzymes between tension and opposite woods of Robinia pseudoacacia L. These findings are well in accord with the chemical structure of lignin in the compression and tension woods of the three species studied: high content of lignin rich in condensed units in compression wood, and little difference in lignin between tension and opposite woods.

SAPS simulation with GITM/UCLA-RCM coupled model

Science.gov (United States)

Lu, Y.; Deng, Y.; Guo, J.; Zhang, D.; Wang, C. P.; Sheng, C.

2017-12-01

Abstract: SAPS simulation with GITM/UCLA-RCM coupled model Author: Yang Lu, Yue Deng, Jiapeng Guo, Donghe Zhang, Chih-Ping Wang, Cheng Sheng Ion velocity in the Sub Aurora region observed by Satellites in storm time often shows a significant westward component. The high speed westward stream is distinguished with convection pattern. These kind of events are called Sub Aurora Polarization Stream (SAPS). In March 17th 2013 storm, DMSP F18 satellite observed several SAPS cases when crossing Sub Aurora region. In this study, Global Ionosphere Thermosphere Model (GITM) has been coupled to UCLA-RCM model to simulate the impact of SAPS during March 2013 event on the ionosphere/thermosphere. The particle precipitation and electric field from RCM has been used to drive GITM. The conductance calculated from GITM has feedback to RCM to make the coupling to be self-consistent. The comparison of GITM simulations with different SAPS specifications will be conducted. The neutral wind from simulation will be compared with GOCE satellite. The comparison between runs with SAPS and without SAPS will separate the effect of SAPS from others and illustrate the impact on the TIDS/TADS propagating to both poleward and equatorward directions.

Surface drag effects on simulated wind fields in high-resolution atmospheric forecast model

Energy Technology Data Exchange (ETDEWEB)

Lim, Kyo Sun; Lim, Jong Myoung; Ji, Young Yong [Environmental Radioactivity Assessment Team,Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Shin, Hye Yum [NOAA/Geophysical Fluid Dynamics Laboratory, Princeton (United States); Hong, Jin Kyu [Yonsei University, Seoul (Korea, Republic of)

2017-04-15

It has been reported that the Weather Research and Forecasting (WRF) model generally shows a substantial over prediction bias at low to moderate wind speeds and winds are too geostrophic (Cheng and Steenburgh 2005), which limits the application of WRF model in the area that requires the accurate surface wind estimation such as wind-energy application, air-quality studies, and radioactive-pollutants dispersion studies. The surface drag generated by the subgrid-scale orography is represented by introducing a sink term in the momentum equation in their studies. The purpose of our study is to evaluate the simulated meteorological fields in the high-resolution WRF framework, that includes the parameterization of subgrid-scale orography developed by Mass and Ovens (2010), and enhance the forecast skill of low-level wind fields, which plays an important role in transport and dispersion of air pollutants including radioactive pollutants. The positive bias in 10-m wind speed is significantly alleviated by implementing the subgrid-scale orography parameterization, while other meteorological fields including 10-m wind direction are not changed. Increased variance of subgrid- scale orography enhances the sink of momentum and further reduces the bias in 10-m wind speed.

Spin-one top partner: phenomenology

Science.gov (United States)

Collins, Jack H.; Jain, Bithika; Perelstein, Maxim; Lorier, Nicolas Rey-Le

2014-08-01

Cai, Cheng, and Terning (CCT) suggested a model in which the left-handed top quark is identified with a gaugino of an extended gauge group, and its superpartner is a spin-1 particle. We perform a phenomenological analysis of this model, with a focus on the spin-1 top partner, which we dub the "swan". We find that precision electroweak fits, together with direct searches for Z ' bosons at the LHC, place a lower bound of at least about 4.5 TeV on the swan mass. An even stronger bound, 10 TeV or above, applies in most of the parameter space, mainly due to the fact that the swan is typically predicted to be significantly heavier than the Z '. We find that the 125 GeV Higgs can be easily accommodated in this model with non-decoupling D-terms. In spite of the strong lower bound on the swan mass, we find that corrections to Higgs couplings to photons and gluons induced by swan loops are potentially observable at future Higgs factories. We also briefly discuss the prospects for discovering a swan at the proposed 100 TeV pp collider.

An examination of the wording effect in the Rosenberg Self-Esteem Scale among culturally Chinese people.

Science.gov (United States)

Wu, Chia-Huei

2008-10-01

Previous psychometric studies of the Rosenberg Self-Esteem Scale (RSES; 1965) have shown that items with positive and negative words tend to form 2 factors instead of a single factor for global self-esteem. Recent studies using confirmatory factor analysis have indicated that there is an additional method effect behind negatively worded items. However, researchers conducted these studies using Western participants. Because J. L. Farh and B. S. Cheng (1997) suggested that culturally Chinese people tend to exhibit a modesty bias in self-evaluation, especially on positively worded items, researchers may infer that a wording effect of positively worded items would be evident for culturally Chinese people. The author examined the wording effect in the RSES for culturally Chinese people by comparing different confirmatory factor models. The author analyzed data from 2 independent samples of students at the National Taiwan University (ns = 393, 441) and a national sample of juniors recruited from 140 universities and colleges in Taiwan in 2004 (n = 28,862). Results showed that in addition to a global factor for self-esteem, method effects of positively and negatively worded items should also be specified for a model fitting culturally Chinese people.

A hidden Markov model approach for determining expression from genomic tiling micro arrays

Directory of Open Access Journals (Sweden)

Krogh Anders

2006-05-01

Full Text Available Abstract Background Genomic tiling micro arrays have great potential for identifying previously undiscovered coding as well as non-coding transcription. To-date, however, analyses of these data have been performed in an ad hoc fashion. Results We present a probabilistic procedure, ExpressHMM, that adaptively models tiling data prior to predicting expression on genomic sequence. A hidden Markov model (HMM is used to model the distributions of tiling array probe scores in expressed and non-expressed regions. The HMM is trained on sets of probes mapped to regions of annotated expression and non-expression. Subsequently, prediction of transcribed fragments is made on tiled genomic sequence. The prediction is accompanied by an expression probability curve for visual inspection of the supporting evidence. We test ExpressHMM on data from the Cheng et al. (2005 tiling array experiments on ten Human chromosomes 1. Results can be downloaded and viewed from our web site 2. Conclusion The value of adaptive modelling of fluorescence scores prior to categorisation into expressed and non-expressed probes is demonstrated. Our results indicate that our adaptive approach is superior to the previous analysis in terms of nucleotide sensitivity and transfrag specificity.

Validation of a Residual Stress Measurement Method by Swept High-Frequency Eddy Currents

International Nuclear Information System (INIS)

Lee, C.; Shen, Y.; Lo, C. C. H.; Nakagawa, N.

2007-01-01

This paper reports on a swept high-frequency eddy current (SHFEC) measurement method developed for electromagnetic nondestructive characterization of residual stresses in shot peened aerospace materials. In this approach, we regard shot-peened surfaces as modified surface layers of varying conductivity, and determine the conductivity deviation profile by inversion of the SHFEC data. The SHFEC measurement system consists of a pair of closely matched printed-circuit-board coils driven by laboratory instrument under software control. This provides improved sensitivity and high frequency performance compared to conventional coils, so that swept frequency EC measurements up to 50 MHz can be made to achieve the smallest skin depth of 80 μm for nickel-based superalloys. We devised a conductivity profile inversion procedure based on the laterally uniform multi-layer theory of Cheng, Dodd and Deeds. The main contribution of this paper is the methodology validation. Namely, the forward and inverse models were validated against measurements on artificial layer specimens consisting of metal films with different conductivities placed on a metallic substrate. The inversion determined the film conductivities which were found to agree with those measured using the direct current potential drop (DCPD) method

Validation of a Residual Stress Measurement Method by Swept High-Frequency Eddy Currents

Science.gov (United States)

Lee, C.; Shen, Y.; Lo, C. C. H.; Nakagawa, N.

2007-03-01

This paper reports on a swept high-frequency eddy current (SHFEC) measurement method developed for electromagnetic nondestructive characterization of residual stresses in shot peened aerospace materials. In this approach, we regard shot-peened surfaces as modified surface layers of varying conductivity, and determine the conductivity deviation profile by inversion of the SHFEC data. The SHFEC measurement system consists of a pair of closely matched printed-circuit-board coils driven by laboratory instrument under software control. This provides improved sensitivity and high frequency performance compared to conventional coils, so that swept frequency EC measurements up to 50 MHz can be made to achieve the smallest skin depth of 80 μm for nickel-based superalloys. We devised a conductivity profile inversion procedure based on the laterally uniform multi-layer theory of Cheng, Dodd and Deeds. The main contribution of this paper is the methodology validation. Namely, the forward and inverse models were validated against measurements on artificial layer specimens consisting of metal films with different conductivities placed on a metallic substrate. The inversion determined the film conductivities which were found to agree with those measured using the direct current potential drop (DCPD) method.

Scaling similarities of multiple fracturing of solid materials

Directory of Open Access Journals (Sweden)

P. G. Kapiris

2004-01-01

Full Text Available It has recently reported that electromagnetic flashes of low-energy -rays emitted during multi-fracturing on a neutron star, and electromagnetic pulses emitted in the laboratory by a disordered material subjected to an increasing external load, share distinctive statistical properties with earthquakes, such as power-law energy distributions (Cheng et al., 1996; Kossobokov et al., 2000; Rabinovitch et al., 2001; Sornette and Helmstetter, 2002. The neutron starquakes may release strain energies up to erg, while, the fractures in laboratory samples release strain energies approximately a fraction of an erg. An earthquake fault region can build up strain energy up to approximately erg for the strongest earthquakes. Clear sequences of kilohertz-megahertz electromagnetic avalanches have been detected from a few days up to a few hours prior to recent destructive earthquakes in Greece. A question that arises effortlessly is if the pre-seismic electromagnetic fluctuations also share the same statistical properties. Our study justifies a positive answer. Our analysis also reveals 'symptoms' of a transition to the main rupture common with earthquake sequences and acoustic emission pulses observed during laboratory experiments (Maes et al., 1998.

Weighted multiscale Rényi permutation entropy of nonlinear time series

Science.gov (United States)

Chen, Shijian; Shang, Pengjian; Wu, Yue

2018-04-01

In this paper, based on Rényi permutation entropy (RPE), which has been recently suggested as a relative measure of complexity in nonlinear systems, we propose multiscale Rényi permutation entropy (MRPE) and weighted multiscale Rényi permutation entropy (WMRPE) to quantify the complexity of nonlinear time series over multiple time scales. First, we apply MPRE and WMPRE to the synthetic data and make a comparison of modified methods and RPE. Meanwhile, the influence of the change of parameters is discussed. Besides, we interpret the necessity of considering not only multiscale but also weight by taking the amplitude into account. Then MRPE and WMRPE methods are employed to the closing prices of financial stock markets from different areas. By observing the curves of WMRPE and analyzing the common statistics, stock markets are divided into 4 groups: (1) DJI, S&P500, and HSI, (2) NASDAQ and FTSE100, (3) DAX40 and CAC40, and (4) ShangZheng and ShenCheng. Results show that the standard deviations of weighted methods are smaller, showing WMRPE is able to ensure the results more robust. Besides, WMPRE can provide abundant dynamical properties of complex systems, and demonstrate the intrinsic mechanism.

Effects of melatonin in experimental stroke models in acute, sub-acute, and chronic stages

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Hsiao-Wen Lin

2009-03-01

Full Text Available Hsiao-Wen Lin, E-Jian LeeNeurophysiology Laboratory, Neurosurgical Service, Department of Surgery, National Cheng Kung University Medical Center and Medical School, Tainan, TaiwanAbstract: Melatonin (N-acetyl-5-methoxy-tryptamine, a naturally occurring indole produced mainly by the pineal gland, is a well known antioxidant. Stroke (cerebral ischemia is the second leading cause of death worldwide. To date, however, effective and safe treatment for stroke remains unavailable. Melatonin is both lipid- and water-soluble and readily crosses the blood–brain barrier (BBB. Increasing evidence has shown that, in animal stroke models, administering melatonin significantly reduces infarct volume, edema, and oxidative damage and improves electrophysiological and behavioral performance. Here, we reviewed studies that assess effects of melatonin on cerebral ischemia in acute, sub-acute, and chronic stages. In addition to its potent antioxidant properties, melatonin exerts antiapoptotic, antiexcitotoxic, anti-inflammatory effects and promotes mitochondrial functions in animals with cerebral ischemia. Given that melatonin shows almost no toxicity to humans and possesses multifaceted protective capacity against cerebral ischemia, it is valuable to consider using melatonin in clinical trials on patients suffering from stroke.Keywords: cerebral ischemia, melatonin, stroke, neuroprotection

Dynamics of a thermo-responsive microgel colloid near to the glass transition

Science.gov (United States)

Di, Xiaojun; Peng, Xiaoguang; McKenna, Gregory B.

2014-02-01

In a previous study, we used diffusing wave spectroscopy (DWS) to investigate the aging signatures of a thermo-sensitive colloidal glass and compared them with those of molecular glasses from the perspective of the Kovacs temperature-jump, volume recovery experiments [X. Di, K. Z. Win, G. B. McKenna, T. Narita, F. Lequeux, S. R. Pullela, and Z. Cheng, Phys. Rev. Lett. 106, 095701 (2011)]. In order to further look into the glassy behavior of colloidal systems, we have synthesized a new core/shell particle with lower temperature sensitivity and studied the aging signatures of concentrated systems, again following Kovacs' protocol. Similar signatures of aging to those observed previously were seen in this new system. Moreover, a systematic study of the temperature dependence of the dynamics of the new system for different weight concentrations was performed and the dynamic fragility index m was determined. We have also explored the use of the properties determined from the DWS measurements to obtain macroscopic rheological parameters - storage modulus G'(ω) and loss modulus G″(ω) - using a generalized Stokes-Einstein approach. The micro-rheological and macro-rheological values are in reasonable agreement.

BIMBINGAN KONSELING HOLISTIK UNTUK MEMBANTU PENYESUAIN DIRI MUALAF TIONGHOA MESJID MUHAMMAD CHENGHO PALEMBANG

Directory of Open Access Journals (Sweden)

Neni Noviza

2015-12-01

Full Text Available This study aims to determine how the adjustment itself on converts . Subjects were converts tionghoa mosque Muhammad Chengho Palembang. This study is a qualitative study with a phenomenological approach . Data were obtained and collected through semi-structured interviews and observations by using the interview guide and checklist list . Then , the data were analyzed using analysis of data reduction , display / presentation of data and making conclusions / verification of interactive models of Miles & Huberman ( 1992 . The results showed that the problems experienced by the Muslim convert Muhammad Cheng Ho Mosque is a matter of family , career and employment issues , and marginalized by other communities. The Individuals who have a religious conversion " more tasks " that adjust from changes in themselves and habits to obtain satisfactory relationships with other people and our environment . The problems associated with the present most fundamental change in the lives of converts after deciding to perform religious conversion requires the adjustment mainly in the habit of worship and in the family who did not convert to the faith of the subject . Holistic counseling through religious counseling and bibliotherapy approach is one way to help the adjustment to convert

Complexation of carboxylate on smectite surfaces.

Science.gov (United States)

Liu, Xiandong; Lu, Xiancai; Zhang, Yingchun; Zhang, Chi; Wang, Rucheng

2017-07-19

We report a first principles molecular dynamics (FPMD) study of carboxylate complexation on clay surfaces. By taking acetate as a model carboxylate, we investigate its inner-sphere complexes adsorbed on clay edges (including (010) and (110) surfaces) and in interlayer space. Simulations show that acetate forms stable monodentate complexes on edge surfaces and a bidentate complex with Ca 2+ in the interlayer region. The free energy calculations indicate that the complexation on edge surfaces is slightly more stable than in interlayer space. By integrating pK a s and desorption free energies of Al coordinated water calculated previously (X. Liu, X. Lu, E. J. Meijer, R. Wang and H. Zhou, Geochim. Cosmochim. Acta, 2012, 81, 56-68; X. Liu, J. Cheng, M. Sprik, X. Lu and R. Wang, Geochim. Cosmochim. Acta, 2014, 140, 410-417), the pH dependence of acetate complexation has been revealed. It shows that acetate forms inner-sphere complexes on (110) in a very limited mildly acidic pH range while it can complex on (010) in the whole common pH range. The results presented in this study form a physical basis for understanding the geochemical processes involving clay-organics interactions.

EFL Writing Apprehension: The Macro or the Micro?

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Mohammad Alnufaie

2013-06-01

Full Text Available This study was part of a doctoral project to explore the writing apprehension levels of 121 second-year undergraduate Saudi student writers who were studying English as a foreign language and for specific purposes in a Saudi industrial college.The study draws on Dörnyei’s (1994 framework of L2 motivation levels and their micro-motivational conditions in L2 learning situations, and addresses EFL writing apprehension in strategy-related conditions. For data collection, aWriting Strategy Apprehension Scale (WSAS was developed and adapted from a test designed by John Daly and Michael Miller (1975 and from the Second Language Writing Anxiety Inventory (SLWAI designed by Cheng (2004.The participants were classified into three levels of apprehension (apprehensive strategy users, average apprehensive strategy users, and low apprehensive strategy users. The results showwhile the majority of the participants (57.9% were average in their stress and apprehension levels towards writing strategies, almost a third of them (31.4% were highly apprehensive. In addition, the most stressful strategies were those that indicate the lack of generating ideas, the care about accuracy, and the follow of teacher’s expectations.

Menopause is associated with self-reported poor sleep quality in women without vasomotor symptoms.

Science.gov (United States)

Hung, Hao-Chang; Lu, Feng-Hwa; Ou, Horng-Yih; Wu, Jin-Shang; Yang, Yi-Ching; Chang, Chih-Jen

2014-08-01

The aim of this study was to investigate the relationship between menopause and self-reported sleep quality in Chinese women without vasomotor symptoms. Cross-sectional data were collected from a decoded database of the National Cheng Kung University Hospital. Menopause was defined as absence of menses for at least 12 months or a history of hysterectomy and oophorectomy. Self-reported sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI). A higher global PSQI score indicates poorer self-reported sleep quality, and a global PSQI score greater than 5 differentiates poor sleepers from good sleepers. Of the 1,088 women recruited, 353 (32.4%) were in postmenopause status. Postmenopausal women had higher mean (SD) global PSQI scores (8.0 [3.3] vs. 6.1 [2.2], P menopause (β = 1.532; 95% CI, 1.135 to 1.949; P menopause (odds ratio, 1.453; 95% CI, 1.030 to 2.051; P menopause and snoring are associated with an increased risk of poor self-reported sleep quality independently of cardiometabolic factors and lifestyle, whereas long sleep duration is associated with a decreased risk of poor self-reported sleep quality.

Beardsley on literature, fiction, and nonfiction

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Szu-Yen Lin

2016-03-01

Full Text Available This paper attempts to revive interest in the speech act theory of literature by looking into Monroe C. Beardsley's account in particular. Beardsley's view in this respect has received, surprisingly, less attention than deserved. I first offer a reconstruction of Beardsley's account and then use it to correct some notable misconceptions. Next, I show that the reformulation reveals a hitherto unnoticed discrepancy in Beardsley's position and that this can be explained away by a weak version of intentionalism that Beardsley himself actually tolerates. Finally, I assess the real difficulty of Beardsley's theory and its relevance today.Szu-Yen Lin is a doctoral candidate in philosophy at the University of Auckland. He received his MA in philosophy from National Chung Cheng University in Taiwan. His research areas include aesthetics and philosophy of the arts, in particular the philosophy of literature. He is currently working on the problem of literary interpretation. Apart from being a philosophy researcher, Szu-Yen is also a mystery writer, having published 8 novels and 28 short stories in Chinese, one of which also appeared in Ellery Queen's Mystery Magazine.

Sustaining the Higher Education Hub Model: The Challenge of Adequate Academic and Social Support Structures for International Students

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Cameron Richards

2011-11-01

Full Text Available In recent years, the Education Hub (EH concept has perhaps become the single most important focus of higher education policy in most Asian countries. A particular Asian Education Hub model (e.g. Cheng, 2010 is now globally influential with its emphasis on how governments can harness direct as well as indirect economic benefits of a higher education system. Such a model aims to prepare students for employment in an emerging global economy and also to attract fee-paying international students in terms of education as not just a public good but a key and increasingly important area of national investment and economic development. In a related paper which focused on a comparison between distinct Malaysian and Singaporean versions of Asian EH l models developed over the last two decades (Richards, 2011c, we investigated the dangers as well as opportunities at stake. In this paper, we investigate the linked idea that sufficient academic and social support structures for supporting international as well as local students provide the crucial key to the factors of sustainability needed to support the various versions of the general strategy of Higher Education internationalisation.

The role of simulation in teaching pediatric resuscitation: current perspectives

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Lin Y

2015-03-01

Full Text Available Yiqun Lin,1 Adam Cheng2 1KidSIM-ASPIRE Simulation Research Program, Alberta Children's Hospital, University of Calgary, Calgary, AB, Canada; 2KidSIM-ASPIRE Research Program, Department of Pediatrics, Division of Emergency Medicine, University of Calgary, Alberta Children's Hospital, Calgary, AB, Canada Abstract: The use of simulation for teaching the knowledge, skills, and behaviors necessary for effective pediatric resuscitation has seen widespread growth and adoption across pediatric institutions. In this paper, we describe the application of simulation in pediatric resuscitation training and review the evidence for the use of simulation in neonatal resuscitation, pediatric advanced life support, procedural skills training, and crisis resource management training. We also highlight studies supporting several key instructional design elements that enhance learning, including the use of high-fidelity simulation, distributed practice, deliberate practice, feedback, and debriefing. Simulation-based training is an effective modality for teaching pediatric resuscitation concepts. Current literature has revealed some research gaps in simulation-based education, which could indicate the direction for the future of pediatric resuscitation research. Keywords: simulation, pediatric resuscitation, medical education, instructional design, crisis resource management, health care

Estimating back to front ratio of wire screen for measurement of thoron decay products

International Nuclear Information System (INIS)

Koli, Amruta; Khandare, Pallavi; Joshi, Manish; Mariam; Khan, Arshad; Sapra, B.K.

2016-01-01

Wire screens are widely used for measuring the fine fraction of radon/thoron decay products. Their capture efficiencies are generally defined at low aerosol concentration conditions as well as at low sampling flow rates. Effect of changes in sampling flow rate and aerosol concentration on wire screen capture efficiencies and counting correction factor has been studied in this work. Controlled experiments have been conducted using two different mesh sizes at two different aerosol concentration conditions. Experimental results were compared with the existing theories for capture efficiencies of wire screens given by Cheng and Yeh (1980) and Alonso et al. (2001); and semi empirical relation for the front to total ratio given by Solomon and Ren (1992). Theoretical predictions have been found to be relatively close to the experimental findings for moderate aerosol conditions but disagreement was observed in case of high aerosol concentration. The possible reasons for these differences have been discussed in this work. - Highlights: • Effect of Fiber Reynolds number on capture efficiency and back to front ratio of wire screen. • Experiments with Thoron decay products at moderate and elevated aerosol concentrations. • Comparison with theoretical estimates. • Fair agreement observed for moderate aerosol concentration.

A comparative study of three tissue-cultured Dendrobium species and their wild correspondences by headspace gas chromatography-mass spectrometry combined with chemometric methods.

Science.gov (United States)

Chen, Nai-Dong; You, Tao; Li, Jun; Bai, Li-Tao; Hao, Jing-Wen; Xu, Xiao-Yuan

2016-10-01

Plant tissue culture technique is widely used in the conservation and utilization of rare and endangered medicinal plants and it is crucial for tissue culture stocks to obtain the ability to produce similar bioactive components as their wild correspondences. In this paper, a headspace gas chromatography-mass spectrometry method combined with chemometric methods was applied to analyze and evaluate the volatile compounds in tissue-cultured and wild Dendrobium huoshanense Cheng and Tang, Dendrobium officinale Kimura et Migo and Dendrobium moniliforme (Linn.) Sw. In total, 63 volatile compounds were separated, with 53 being identified from the three Dendrobium spp. Different provenances of Dendrobiums had characteristic chemicals and showed remarkable quantity discrepancy of common compositions. The similarity evaluation disclosed that the accumulation of volatile compounds in Dendrobium samples might be affected by their provenance. Principal component analysis showed that the first three components explained 85.9% of data variance, demonstrating a good discrimination between samples. Gas chromatography-mass spectrometry techniques, combined with chemometrics, might be an effective strategy for identifying the species and their provenance, especially in the assessment of tissue-cultured Dendrobium quality for use in raw herbal medicines. Copyright © 2016. Published by Elsevier B.V.

A comparative study of three ternary complexes prepared in different mixing orders of siRNA/redox-responsive hyperbranched poly (amido amine/hyaluronic acid

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Chen CJ

2012-07-01

Full Text Available Cheng-Jun Chen,1 Zhi-Xia Zhao,1 Jian-Cheng Wang,1 En-Yu Zhao,1 Ling-Yan Gao,1 Shu-Feng Zhou,2 Xiao-Yan Liu,1 Wan-Liang Lu,1 Qiang Zhang11State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmaceutics, School of Pharmaceutical Science, Peking University, Beijing, People’s Republic of China; 2Department of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, FL, USAAbstract: In this study, a novel redox-responsive hyperbranched poly(amido amine (named PCD was synthesized and used as a cationic polymer to form a ternary complex with small interfering RNA (siRNA and hyaluronic acid (HA for siRNA delivery. Here, it is hypothesized that different mixing orders result in different assembly structures, which may affect the siRNA delivery efficiency. To investigate the effects of mixing orders on siRNA delivery efficiency in two human breast cancer cell lines, three ternary complexes with different mixing orders of siRNA/PCD/HA were prepared and characterized: mixing order I (initially prepared siRNA/PCD binary complex further coated by negatively charged HA, mixing order II (initially prepared HA/PCD binary complex further incubated with siRNA, and mixing order III (initially prepared siRNA/HA mixture further electrostatically compacted by positively charged PCD. With an optimized siRNA/PCD/HA charge ratio of 1/20/16, the particle sizes and zeta potentials of these ternary complexes were 124.8 nm and 27.3 mV (mixing order I, 147.5 nm and 29.9 mV (mixing order II, and 128.8 nm and 19.4 mV (mixing order III. Also, the effects on stability, cellular uptake, and gene silencing efficiency of siRNA formulated in ternary complexes with different mixing orders were investigated. The results showed that mixing orders I and III displayed better siRNA transfection and protection than mixing order II in human breast cancer MCF-7 and MDA-MB-231 cells. More interesting, at the siRNA/PCD/HA charge ratio of 1/20/16, the

Rivastigmine: the advantages of dual inhibition of acetylcholinesterase and butyrylcholinesterase and its role in subcortical vascular dementia and Parkinson’s disease dementia

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Kandiah N

2017-04-01

Full Text Available Nagaendran Kandiah,1,2 Ming-Chyi Pai,3,4 Vorapun Senanarong,5 Irene Looi,6,7 Encarnita Ampil,8 Kyung Won Park,9 Ananda Krishna Karanam,10 Stephen Christopher11 1Department of Neurology, National Neuroscience Institute, Tan Tock Seng Hospital, 2Duke-NUS, Graduate Medical School, Singapore; 3Division of Behavioral Neurology, Department of Neurology, 4Alzheimer’s Disease Research Center, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan City, Taiwan; 5Division of Neurology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand; 6Clinical Research Centre, 7Department of Medicine, Hospital Seberang Jaya, Penang, Malaysia; 8Department of Neurology and Psychiatry, Faculty of Medicine and Surgery, University of Santo Tomas, Manila, Philippines; 9Department of Neurology and Cognitive Disorders and Dementia Center, Institute of Convergence Bio-Health, Dong-A University College of Medicine, Busan, Republic of Korea; 10Novartis Healthcare Private Limited, Hyderabad, India; 11Novartis (Singapore Pte. Ltd., Singapore Abstract: Several studies have demonstrated clinical benefits of sustained cholinesterase inhibition with rivastigmine in Alzheimer’s disease (AD and Parkinson’s disease dementia (PDD. Unlike donepezil and galantamine that selectively inhibit acetylcholinesterase (AChE; EC 3.1.1.7, rivastigmine is a unique cholinesterase inhibitor with both AChE and butyrylcholinesterase (BuChE; EC 3.1.1.8 inhibitory activity. Rivastigmine is also available as transdermal patch that has been approved by the US Food and Drug Administration for the treatment of mild, moderate, and severe AD as well as mild-to-moderate PDD. In this review, we explore the role of BuChE inhibition in addition to AChE inhibition with rivastigmine in the outcomes of cognition, global function, behavioral symptoms, and activities of daily living. Additionally, we review the evidence supporting the use of dual

IQ discrepancy differentiates levels of fine motor skills and their relationship in children with autism spectrum disorders

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Yu TY

2018-02-01

Full Text Available Tzu-Ying Yu,1 Willy Chou,2,3 Julie Chi Chow,4 Chien-Ho Lin,5 Li-Chen Tung,2,6 Kuan-Lin Chen7,8 1Department of Occupational Therapy, College of Medicine, I-Shou University, Kaohsiung, 2Department of Physical Medicine and Rehabilitation, Chi-Mei Medical Center, 3Department of Recreation and Health Care Management, Cha Nan University of Pharmacy and Science, 4Department of Pediatrics, 5Department of Psychiatry, Chi Mei Medical Center, Tainan, 6Department of Physical Medicine and Rehabilitation, Da Chien General Hospital, Miaoli, 7Department of Occupational Therapy, College of Medicine, National Cheng Kung University, 8Department of Physical Medicine and Rehabilitation, National Cheng Kung University Hospital, Tainan, Taiwan Purpose: We investigated 1 the impact of differences in intelligence quotient discrepancy (IQD on motor skills of preschool-aged children with autism spectrum disorders (ASD; 2 the relationships between IQD and motor skills in preschool-aged children with ASD. Methods: A total of 127 ASD preschool-aged children were divided into three groups according to the size of the IQD: IQD within 1 standard deviation (1SD; EVENIQ; n=81, discrepantly higher verbal intelligence quotient (VIQ; n=22; VIQ>performance intelligence quotient [PIQ] above 1SD [≥15 points], and discrepantly higher PIQ (n=24; PIQ>VIQ above 1SD [≥15 points]. Children’s IQD and motor skills were determined with the Wechsler Preschool and Primary Scale of Intelligence™ – Fourth Edition and the motor subtests of the Comprehensive Developmental Inventory for Infants and Toddlers (CDIIT, respectively. Results: One-way analysis of variance revealed significant group differences for the fine motor domain of the CDIIT and the visual–motor coordination subtest (F=3.37–4.38, p<0.05. Children with discrepantly higher PIQ were associated with better fine motor skills than were children with even IQD and those with discrepantly higher VIQ, and vice versa. IQD (PIQ �

Lasteaia ja lõbumaja vahel : eesti proosa 2008 / Vaapo Vaher

Index Scriptorium Estoniae

Vaher, Vaapo, 1945-

2009-01-01

Ülevaade 2008. aasta eesti proosast. Pikemalt käsitletakse järgmisi autoreid ja nende teoseid: Mihkel Raud "Musta pori näkku", Olev Remsu "Musketäride muundumised", Rein Põder "Juba olnud", Juhan Nurme "Ligimene", Jaan Tangsoo "Méduse'i parv", Esta Aksli "Tare poole tõttaja", Mari Saat "Lasnamäe lunastaja", Peeter Morgen "Sõnum", Mait Raun "Dr. Mööbi seiklused Inglismaal", Andrei Hvostov "Võõrad lood" ja "Projektijuht Posse", Chaneldior "Kontrolli alt väljas", Vahur Afanasjev "Kosmos", Egon Ilisson "Isased", Jaak Leer "Kaks kabanossi ja Maaja", Kärt Hellerma "Sinine missa", Elo Viiding "Püha Maama", Toomas Raudam "Miks ma ei taha olla kirjanik?", Mart Kivastik "Kurb raamat", Jüri Tuulik "Räim, pisike kena kala", Tarmo Teder "12 jõulujuttu", Dagmar Lamp (koostaja) "Tule, ma jutustan sulle loo", Eia Uus "Kahe näoga jumal", Barthol Lo Mejor "Popdada 2007-2008", Anti Saar "Nemad kaks", Ketlin Priilinn "Liiseli võti" ja "Vaim", Aita Kivi "Lähedal", Marje Ernits "Hoia mu kätt", Kati Murutar "Naisena sündinud : kakskümmend aastat hiljem", Tuule Lind "Pööratud tuul", Siiri Laidla "Lihtne lugu, ehk, Senta suvepuhkus", Kätlin Padesaar "Veel üks paradiis", Aimée Beekman "Proovielu", Lehte Hainslau "Kolmkõla, ehk, 3 kõla", Ira Lember "Ööviiulid", Tamur Kusnets "Hundipäikese aeg : metsiku jahi algus", Kaupo Pähkel "Ehatähe rüütel", Arvo Valton "Ülemiste vanake", Tiit Aleksejev "Palveränd", Ants Eret "Afgaanide vang", Mario Merirand "Afganistani päevik", Leo Kunnas "Gort Ashryn", Rein Raud "Vend", Peeter Sauter "Beibi bluu", Marion Andra "Pimend", Kristjan Sander "13 talvist hetke", Helga Nõu "Peaaegu geenius, ehk, Schrödingeri kassi otsimas", Tiit Sepa "Eefa hüüdnimega Siug", Kaarel ja Klaara Kivi "Varandus seinal", Merike Jürjo "Mälestusteta maja", Rein Vahisalu "Viies kabinet", Aarne Biin "Mees otsib naist", Erik Tohvri "Ümberasujad" ja "Sulasest sai peremees", Arnold Laugus "Elav maa", Jüri v. Grauberg "Selguse poole", J�

Lasteaia ja lõbumaja vahel : Eesti proosa 2008 / Vaapo Vaher

Index Scriptorium Estoniae

Vaher, Vaapo, 1945-

2012-01-01

Ülevaade 2008. aasta eesti proosast. Pikemalt käsitletakse järgmisi autoreid ja nende teoseid: Mihkel Raud "Musta pori näkku", Olev Remsu "Musketäride muundumised", Rein Põder "Juba olnud", Juhan Nurme "Ligimene", Jaan Tangsoo "Méduse'i parv", Esta Aksli "Tare poole tõttaja", Mari Saat "Lasnamäe lunastaja", Peeter Morgen "Sõnum", Mait Raun "Dr. Mööbi seiklused Inglismaal", Andrei Hvostov "Võõrad lood" ja "Projektijuht Posse", Chaneldior "Kontrolli alt väljas", Vahur Afanasjev "Kosmos", Egon Ilisson "Isased", Jaak Leer "Kaks kabanossi ja Maaja", Kärt Hellerma "Sinine missa", Elo Viiding "Püha Maama", Toomas Raudam "Miks ma ei taha olla kirjanik?", Mart Kivastik "Kurb raamat", Jüri Tuulik "Räim, pisike kena kala", Tarmo Teder "12 jõulujuttu", Dagmar Lamp (koostaja) "Tule, ma jutustan sulle loo", Eia Uus "Kahe näoga jumal", Barthol Lo Mejor "Popdada 2007-2008", Anti Saar "Nemad kaks", Ketlin Priilinn "Liiseli võti" ja "Vaim", Aita Kivi "Lähedal", Marje Ernits "Hoia mu kätt", Kati Murutar "Naisena sündinud : kakskümmend aastat hiljem", Tuule Lind "Pööratud tuul", Siiri Laidla "Lihtne lugu, ehk, Senta suvepuhkus", Kätlin Padesaar "Veel üks paradiis", Aimée Beekman "Proovielu", Lehte Hainslau "Kolmkõla, ehk, 3 kõla", Ira Lember "Ööviiulid", Tamur Kusnets "Hundipäikese aeg : metsiku jahi algus", Kaupo Pähkel "Ehatähe rüütel", Arvo Valton "Ülemiste vanake", Tiit Aleksejev "Palveränd", Ants Eret "Afgaanide vang", Mario Merirand "Afganistani päevik", Leo Kunnas "Gort Ashryn", Rein Raud "Vend", Peeter Sauter "Beibi bluu", Marion Andra "Pimend", Kristjan Sander "13 talvist hetke", Helga Nõu "Peaaegu geenius, ehk, Schrödingeri kassi otsimas", Tiit Sepa "Eefa hüüdnimega Siug", Kaarel ja Klaara Kivi "Varandus seinal", Merike Jürjo "Mälestusteta maja", Rein Vahisalu "Viies kabinet", Aarne Biin "Mees otsib naist", Erik Tohvri "Ümberasujad" ja "Sulasest sai peremees", Arnold Laugus "Elav maa", Jüri v. Grauberg "Selguse poole", J�

Design of books inventory with RFID antenna in library management system

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Cheng Ching-Chien

2017-01-01

Full Text Available A 915 MHz printed radio-frequency-identification (RFID antennas with the characteristics of good gain and omnidirectional beam wave is constructed and evaluated in this study. The objective is to find out their best reading rates for providing effective wireless communications among RFID antenna during the library book inventory process. And an optimal library inventory system which is based on electromagnetic identification (EMID technology is proposed, which is constructed to find the optimal tag location for a book, test the tag readability for bookshelves, and connect a couple of multi-layer bookshelves with multiplexers and updat the tag reading status in the database of the computer terminal. The fabricated antenna reader and the proposed system are embedded into different locations of bookshelves and tested at the library of Cheng Shiu University in Taiwan. According to the experimental results, the designed prototype of the antenna reader has the characteristics of the directional radiation pattern, good gain, simple shape, low cost and is easy to be integrated into the bookshelf. And the designed library inventory system can authenticate the location of a book automatically. They can benefit administrating librarians with the capabilities of decreasing the library inventory processing time and reducing the possibility of the books being misplaced.

The influence of asymmetry on mix in direct-drive inertial confinement fusion experiments

International Nuclear Information System (INIS)

Christensen, C.R.; Wilson, D.C.; Barnes, Cris W.; Grim, G.P.; Morgan, G.L.; Wilke, M.D.; Marshall, F.J.; Glebov, V.Yu.; Stoeckl, C.

2004-01-01

The mix of shell material into the fuel of inertial confinement fusion (ICF) implosions is thought to be a major cause of the failure of most ICF experiments to achieve the fusion yield predicted by computer codes. Implosion asymmetry is a simple measurable quantity that is expected to affect the mix. In order to measure the coupling of asymmetry to mix in ICF implosions, we have performed experiments on the OMEGA laser [T. R. Boehly et al., Rev. Sci. Instrum. 66, 508 (1995)] that vary the energy of each of the sixty beams individually to achieve a given fraction of L2, the second-order Legendre polynomial. Prolate, symmetric, and oblate implosions resulted. Three different fill pressures were used. Simultaneous x-ray and neutron images were obtained. The experiments were modeled with a radiation/hydrodynamics code using the multi-fluid interpenetration mix model of Scannapieco and Cheng. It fits the data well with a single value of its one adjustable parameter (0.07±0.01). This agreement is demonstrated by neutron yield, x-ray images, neutron images, and ion temperatures. The degree of decline of the neutron yield with asymmetry at different fill pressures provides a hard constraint on ICF mix modeling

Effect of the forcing term in the pseudopotential lattice Boltzmann modeling of thermal flows.

Science.gov (United States)

Li, Qing; Luo, K H

2014-05-01

The pseudopotential lattice Boltzmann (LB) model is a popular model in the LB community for simulating multiphase flows. Recently, several thermal LB models, which are based on the pseudopotential LB model and constructed within the framework of the double-distribution-function LB method, were proposed to simulate thermal multiphase flows [G. Házi and A. Márkus, Phys. Rev. E 77, 026305 (2008); L. Biferale, P. Perlekar, M. Sbragaglia, and F. Toschi, Phys. Rev. Lett. 108, 104502 (2012); S. Gong and P. Cheng, Int. J. Heat Mass Transfer 55, 4923 (2012); M. R. Kamali et al., Phys. Rev. E 88, 033302 (2013)]. The objective of the present paper is to show that the effect of the forcing term on the temperature equation must be eliminated in the pseudopotential LB modeling of thermal flows. First, the effect of the forcing term on the temperature equation is shown via the Chapman-Enskog analysis. For comparison, alternative treatments that are free from the forcing-term effect are provided. Subsequently, numerical investigations are performed for two benchmark tests. The numerical results clearly show that the existence of the forcing-term effect will lead to significant numerical errors in the pseudopotential LB modeling of thermal flows.

Help-Seeking Intentions among Asian American and White American Students in Psychological Distress: Application of the Health Belief Model

Science.gov (United States)

Kim, Jin E.; Zane, Nolan

2015-01-01

Objective Underutilization of needed mental health services continues to be the major mental health disparity affecting Asian Americans (Sue, Cheng, Saad, & Chu, 2012). The goal of the study was to apply a social psychological theoretical framework—the Health Belief Model (Rosenstock, 1966)—to understand potential reasons why Asian Americans underutilize mental health services relative to White Americans. Method Using a cross-sectional online questionnaire, this study examined how perceived severity of symptoms, perceived susceptibility to mental health problems, perceived benefits of treatment, and perceived barriers to treatment influenced intentions to seek help among a sample of 395 Asian American and 261 White American students experiencing elevated levels of psychological distress. Results Analyses using structural equation modeling indicated that Asian Americans in distress had relatively lower intentions to seek help compared to White Americans. Perceived benefits partially accounted for differences in help-seeking intentions. Although Asian Americans perceived greater barriers to help-seeking than White Americans, it did not significantly explain racial/ethnic differences in help-seeking intentions. Perceived severity and barriers were related to help-seeking intentions in both groups. Conclusions Outreach efforts that particularly emphasize the benefits of seeking mental health services may be a particularly promising approach to address underutilization. These findings have implications in help-seeking promotion and outreach. PMID:26098454

Modeling and analysis of large-eddy simulations of particle-laden turbulent boundary layer flows

KAUST Repository

Rahman, Mustafa M.

2017-01-05

We describe a framework for the large-eddy simulation of solid particles suspended and transported within an incompressible turbulent boundary layer (TBL). For the fluid phase, the large-eddy simulation (LES) of incompressible turbulent boundary layer employs stretched spiral vortex subgrid-scale model and a virtual wall model similar to the work of Cheng, Pullin & Samtaney (J. Fluid Mech., 2015). This LES model is virtually parameter free and involves no active filtering of the computed velocity field. Furthermore, a recycling method to generate turbulent inflow is implemented. For the particle phase, the direct quadrature method of moments (DQMOM) is chosen in which the weights and abscissas of the quadrature approximation are tracked directly rather than the moments themselves. The numerical method in this framework is based on a fractional-step method with an energy-conservative fourth-order finite difference scheme on a staggered mesh. This code is parallelized based on standard message passing interface (MPI) protocol and is designed for distributed-memory machines. It is proposed to utilize this framework to examine transport of particles in very large-scale simulations. The solver is validated using the well know result of Taylor-Green vortex case. A large-scale sandstorm case is simulated and the altitude variations of number density along with its fluctuations are quantified.

Study on Writing Anxiety among Iranian EFL Students

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Naghmeh Jebreil

2015-03-01

Full Text Available This article aimed at investigating the level of writing anxiety of the Iranian EFL students with different proficiency levels. To do so, 45 students (elementary, intermediate, and advanced learners studying in Azad University of Ilam, Iran were selected based on random sampling. Second, Language Writing Anxiety Inventory SLWAI (Cheng, 2004 was used to measure anxiety.  Both descriptive and inferential statistics including One-way ANOVA were run to analyze the data. Statistical analysis was conducted using Statistical Package for Social Science (SPSS. The results of the study indicated that the selected Iranian EFL students majoring in English language teaching experienced a high level of anxiety. In addition, students with elementary level were found to suffer higher level of English writing anxiety than the students with intermediate and advanced levels. Finally, based on the findings, cognitive anxiety was the most common type of anxiety, followed by somatic anxiety, and avoidance behavior. The results also highlighted the fact that foreign and second language teachers should be cautious of the dangers of  anxiety  and try  to  make  the  atmosphere  of  class  as  stress-free  as possible  in  order  to  improve  students’ performance.

Controlling material reactivity using architecture

Science.gov (United States)

Sullivan, Kyle

2017-06-01

The reactivity of thermites can be tailored through selection of several parameters, and can range from very slow burns to rapid deflagrations. 3D printing is a rapidly emerging field, and offers the potential to build architected parts. Here we sought to explore whether controlling such features could be a suitable path forward for gaining additional control of the reactivity. This talk discusses several new methods for preparing thermite samples with controlled architectures using 3D printing. Additionally, we demonstrate that the architecture can play a role in the reactivity of an object. Our results suggest that architecture can be used to tailor the convective and/or advective energy transport during a deflagration, thus enhancing or retarding the reaction. The results are promising in that they give researchers an additional way of controlling the energy release rate without defaulting to the conventional approach of changing the formulation. This work was performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under contract DE-AC52-07NA27344. LLNL-ABS-708525. In collaboration with: Cheng Zhu, Eric Duoss, Matt Durban, Alex Gash, Alexandra Golobic, Michael Grapes, David Kolesky, Joshua Kuntz, Jennifer Lewis, Christopher Spadaccini; LAWRENCE LIVERMORE NATIONAL LAB.

Transverse masses and kinematic constraints: from the boundary to the crease

International Nuclear Information System (INIS)

Barr, Alan J.; Gripaios, Ben; Lester, Christopher G.

2009-01-01

We re-examine the kinematic variable m T2 and its relatives in the light of recent work by Cheng and Han. Their proof that m T2 admits an equivalent, but implicit, definition as the 'boundary of the region of parent and daughter masses that is kinematically consistent with the event hypothesis' is far-reaching in its consequences. We generalize their result both to simpler cases (m T , the transverse mass) and to more complex cases (m TGen ). We further note that it is possible to re-cast many existing and unpleasant proofs (e.g. those relating to the existence or properties of 'kink' and 'crease' structures in m T2 ) into almost trivial forms by using the alternative definition. Not only does this allow us to gain better understanding of those existing results, but it also allows us to write down new (and more or less explicit) definitions of (a) the variable that naturally generalizes m T2 to the case in which the parent or daughter particles are not identical, and (b) the inverses of m T and m T2 - which may be useful if daughter masses are known and bounds on parent masses are required. We note the implications that these results may have for future matrix-element likelihood techniques.

On the species status of the root-knot nematode Meloidogyne ulmi Palmisano & Ambrogioni, 2000 (Nematoda, Meloidogynidae

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Mohammed Ahmed

2013-12-01

Full Text Available The root-knot nematode Meloidogyne ulmi is synonymised with Meloidogyne mali based on morphological and morphometric similarities, common hosts, as well as biochemical similarities at both protein and DNA levels. M. mali was first described in Japan on Malus prunifolia Borkh.; and M. ulmi in Italy on Ulmus chenmoui W.C. Cheng. Morphological and morphometric studies of their holo- and paratypes revealed important similarities in the major characters as well as some general variability in a few others. Host test also showed that besides the two species being able to parasitize the type hosts of the other, they share some other common hosts. Our study of the esterase and malate dehydrogenase isozyme phenotypes of some M. ulmi populations gave a perfectly comparable result to that already known for M. mali. Finally, phylogenetic studies of their SSU and LSU rDNA sequence data revealed that the two are not distinguishable at DNA level. All these put together, leave strong evidences to support the fact that M. ulmi is not a valid species, but a junior synonym of M. mali. Brief discussion on the biology and life cycle of M. mali is given. An overview of all known hosts and the possible distribution of M. mali in Europe are also presented.

How does cognitive dissonance influence the sunk cost effect?

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Chung SH

2018-03-01

Full Text Available Shao-Hsi Chung,1 Kuo-Chih Cheng2 1Department of Business Administration, Meiho University, Pingtung, Taiwan; 2Department of Accounting, National Changhua University of Education, Changhua City, Taiwan Background: The sunk cost effect is the scenario when individuals are willing to continue to invest capital in a failing project. The purpose of this study was to explain such irrational behavior by exploring how sunk costs affect individuals’ willingness to continue investing in an unfavorable project and to understand the role of cognitive dissonance on the sunk cost effect. Methods: This study used an experimental questionnaire survey on managers of firms listed on the Taiwan Stock Exchange and Over-The-Counter. Results: The empirical results show that cognitive dissonance does not mediate the relationship between sunk costs and willingness to continue an unfavorable investment project. However, cognitive dissonance has a moderating effect, and only when the level of cognitive dissonance is high does the sunk cost have significantly positive impacts on willingness to continue on with an unfavorable investment. Conclusion: This study offers psychological mechanisms to explain the sunk cost effect based on the theory of cognitive dissonance, and it also provides some recommendations for corporate management. Keywords: sunk costs, sunk cost effect, cognitive dissonance, behavior, unfavorable investment

The determinants of intra-regional trade in the Western Balkans

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Jelena Trivić

2015-06-01

Full Text Available The purpose of this paper is to identify factors that have an influence on bilateral trade among the Western Balkan countries for the period from 1995 to 2012. Unlike a majority of works that have dealt with the subject of trade in the Balkans or the SEEs, not only geographical, economic or political factors are taken into account, but also factors constituting cultural, communicational and historical types of the so-called “distance” between countries. In order to assess their influence on trade values, an augmented version of the gravity model is employed. It was estimated threefold: as pooled data by OLS, as a random effects model and as a fixed effects model with an additional estimation of time-invariant variables following the method of Cheng and Wall (2005. The results of the research are surprising, as the strongest influence on trade values were exhibited by variables representing ease of a direct communication and similarity of religious structures. In addition, war and one-year-post-war effect showed a strong and statistically important influence. Thus, the main conclusion is that non-economic factors in the region of the Western Balkans play the most important role in determining trade values between countries.

Report on UQ Assessmentsto support SESAME wire-wrappedbundle experiment

Energy Technology Data Exchange (ETDEWEB)

Popov, Emilian L. [ORNL; Pointer, William David [ORNL

2017-10-01

This work assesses the influence of assumptions made when generating a mesh of a wire-wrappedgeometry. The contact region between a wire and its adjacent pin is commonly modeled by eitherembedding the wire to the adjacent pin or trimming the wire so that a gap separates the wire from itsadjacent pin. These models are referred to as close-gap and open-gap approaches herein and are applied totwo geometries. The first geometry consists of a single pin wire-wrapped subchannel. A polyhedral meshand a hexahedral mesh are generated. The second and third geometry are a 7-pin and a 19-pinwire-wrapped bundles meshed with polyhedral elements only. Pressure drops are obtained with theSTAR-CCM+computational fluid dynamic package. Sensitivity analyses of the mesh density, the meshtype, and the turbulent models are performed. Numerical results show that the best match to theexperimental data and to the Cheng-Todreas correlation is obtained with the combination of a hexahedralmesh, the shear stress transport (SST) turbulent model, and the open-gap approach. In the case of the 7-pingeometry, the best results are obtained with the open-gap approach and the SST turbulent model. The19-pin geometry yields contradictory results to the 7-pin geometry results, and thus will require furtherinvestigations.

Exceptionally elevated triglyceride in severe lipemia retinalis

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Yin HY

2016-10-01

Full Text Available Han Y Yin,1–3 Roberto Warman,2,4 Edward H Suh,2 Anny MS Cheng2,3 1Wayne State University, School of Medicine, Detroit, MI, 2Department of Ophthalmology, Florida International University, Herbert Wertheim College of Medicine, 3Ocular Surface Center, Miami, 4Division of Pediatric Ophthalmology, Nicklaus Children’s Hospital, Miami, FL, USA Purpose: To report a case of successful treatment for severe lipemia retinalis with extreme severe hypertriglyceridemia (sHTG.Design: Observational case report.Observations: A 6-week-old infant with severe lipemia retinalis manifested diffuse creamy retinal vessels complicated with vulvar xanthomas. Extreme sHTG with 185-folds of the normal level was reported. Chromosome microarray and lipid gene sequencing confirmed a homozygous lipoprotein lipase gene coding mutation.Results: Under strict adherence to a high medium-chain triglycerides formula and discontinuation of breast milk, the lipemia retinalis and vulval lesions resolved along with a stable plasma lipid level throughout the follow-up period of 6 months.Conclusion: Strict adherence to a low-fat diet without breast milk appears to be effective in treating infants with severe lipemia retinalis associated with exceptionally high triglycerides. Keywords: hypertriglyceride, infant, lipemia retinalis, lipoprotein lipase gene

Automatic telangiectasia analysis in dermoscopy images using adaptive critic design.

Science.gov (United States)

Cheng, B; Stanley, R J; Stoecker, W V; Hinton, K

2012-11-01

Telangiectasia, tiny skin vessels, are important dermoscopy structures used to discriminate basal cell carcinoma (BCC) from benign skin lesions. This research builds off of previously developed image analysis techniques to identify vessels automatically to discriminate benign lesions from BCCs. A biologically inspired reinforcement learning approach is investigated in an adaptive critic design framework to apply action-dependent heuristic dynamic programming (ADHDP) for discrimination based on computed features using different skin lesion contrast variations to promote the discrimination process. Lesion discrimination results for ADHDP are compared with multilayer perception backpropagation artificial neural networks. This study uses a data set of 498 dermoscopy skin lesion images of 263 BCCs and 226 competitive benign images as the input sets. This data set is extended from previous research [Cheng et al., Skin Research and Technology, 2011, 17: 278]. Experimental results yielded a diagnostic accuracy as high as 84.6% using the ADHDP approach, providing an 8.03% improvement over a standard multilayer perception method. We have chosen BCC detection rather than vessel detection as the endpoint. Although vessel detection is inherently easier, BCC detection has potential direct clinical applications. Small BCCs are detectable early by dermoscopy and potentially detectable by the automated methods described in this research. © 2011 John Wiley & Sons A/S.

Aptamer-conjugated PEGylated quantum dots targeting epidermal growth factor receptor variant III for fluorescence imaging of glioma

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Tang J

2017-05-01

Full Text Available Jiaze Tang,1 Ning Huang,1 Xiang Zhang,1,2 Tao Zhou,3 Ying Tan,1,4 Jiangli Pi,5 Li Pi,1 Si Cheng,6 Huzhi Zheng,5 Yuan Cheng1 1Department of Neurosurgery, The Second Affiliated Hospital of Chongqing Medical University, 2Chongqing Key Laboratory of Ultrasound Molecular Imaging, Institute of Ultrasound Imaging, 3Chongqing Key Laboratory of Biochemistry and Molecular Pharmacology, 4Institute of Life Sciences, Chongqing Medical University, 5Key Laboratory on Luminescent and Real-Time Analytical Chemistry, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, 6Department of Orthopaedics, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China Abstract: The extent of resection is a significant prognostic factor in glioma patients. However, the maximum safe resection level is difficult to determine due to the inherent infiltrative character of tumors. Recently, fluorescence-guided surgery has emerged as a new technique that allows safe resection of glioma. In this study, we constructed a new kind of quantum dot (QD-labeled aptamer (QD-Apt nanoprobe by conjugating aptamer 32 (A32 to the QDs surface, which can specially bind to the tumors. A32 is a single-stranded DNA capable of binding to the epidermal growth factor receptor variant III (EGFRvIII specially distributed on the surface of glioma cells. To detect the expression of EGFRvIII in human brain tissues, 120 specimens, including 110 glioma tissues and 10 normal brain tissues, were examined by immunohistochemistry, and the results showed that the rate of positive expression of EGFRvIII in the glioma tissues was 41.82%, and 0.00% in normal brain tissues. Besides, the physiochemical properties of QD-Apt nanoparticles (NPs were thoroughly characterized. Biocompatibility of the NPs was evaluated, and the results suggested that the QD-Apt was nontoxic in vivo and vitro. Furthermore, the use of the QD-Apt in labeling

Dynamics of Soil CO2 Profiles of Pinus sylvestris var. sylvestriformis Seedlings Under CO2 Concentration Doubled%CO2倍增条件下长白赤松幼苗土壤CO2廓线的动态

Institute of Scientific and Technical Information of China (English)

韩士杰; 张军辉; 周玉梅; 邹春静

2002-01-01

The gas-well system permanently installed in the soil was adopted for studying the dynamic relationship between CO2 profiles and seedling root growth of Pinus sylvestris var. sylvestriformis (Takenouchi) Cheng et C. D. Chu. The study was conducted in the Open Research Station of Changbai Mountain Forest Ecological System, The Chinese Academy of Sciences from 1999 to 2001. Four treatments were arranged in the rectangular open-top chambers (OTCs): ambient CO2+no-seedling, 700 μmol/mol CO2+no-seedling, ambient CO2 +seedlings, 700 μmol/mol CO2+seedlings. By collecting and analyzing soil gas synchronously, it was found that the dynamics of CO2 profiles were related to the biological activity of seedlings. There were more roots distributed in the top soil and the boundary layer across soil and sand, which made more contributions to the CO2 profiles due to respiration root. Compared with the ambient CO2, elevated CO2 led to the peak of CO2 concentration distribution shifted from soil surface layer to the boundary layer as seasonally growing of seedling roots. It is suggested the gas-well system is an inexpensive, non-destructive and relatively sensitive method for study of soil CO2 concentration profiles.%采用固定在土壤中的气井系统,监测土壤剖面的CO2动态及其与长白赤松 (Pinus sylvestris var. sylvestriformis (Takenouchi) Cheng et C. D. Chu) 幼苗根系发展之间的关系.实验研究共设4种CO2处理,分别是环境CO2浓度,无苗;CO2为700 μmol/mol,无苗;环境CO2浓度,有苗;CO2为700 μmol/mol,有苗.通过对土壤剖面CO2气体的同步采集与分析表明:土壤CO2廓线与幼苗根系的生物活性密切相关.在土壤表面及壤土和沙土的边界层中,根系分布密集,根系的呼吸作用对那两个土层CO2贡献大;随着幼苗的季节生长,与环境CO2浓度比较,CO2倍增将导致土壤剖面上CO2�

Climate Simulations from Super-parameterized and Conventional General Circulation Models with a Third-order Turbulence Closure

Science.gov (United States)

Xu, Kuan-Man; Cheng, Anning

2014-05-01

A high-resolution cloud-resolving model (CRM) embedded in a general circulation model (GCM) is an attractive alternative for climate modeling because it replaces all traditional cloud parameterizations and explicitly simulates cloud physical processes in each grid column of the GCM. Such an approach is called "Multiscale Modeling Framework." MMF still needs to parameterize the subgrid-scale (SGS) processes associated with clouds and large turbulent eddies because circulations associated with planetary boundary layer (PBL) and in-cloud turbulence are unresolved by CRMs with horizontal grid sizes on the order of a few kilometers. A third-order turbulence closure (IPHOC) has been implemented in the CRM component of the super-parameterized Community Atmosphere Model (SPCAM). IPHOC is used to predict (or diagnose) fractional cloudiness and the variability of temperature and water vapor at scales that are not resolved on the CRM's grid. This model has produced promised results, especially for low-level cloud climatology, seasonal variations and diurnal variations (Cheng and Xu 2011, 2013a, b; Xu and Cheng 2013a, b). Because of the enormous computational cost of SPCAM-IPHOC, which is 400 times of a conventional CAM, we decided to bypass the CRM and implement the IPHOC directly to CAM version 5 (CAM5). IPHOC replaces the PBL/stratocumulus, shallow convection, and cloud macrophysics parameterizations in CAM5. Since there are large discrepancies in the spatial and temporal scales between CRM and CAM5, IPHOC used in CAM5 has to be modified from that used in SPCAM. In particular, we diagnose all second- and third-order moments except for the fluxes. These prognostic and diagnostic moments are used to select a double-Gaussian probability density function to describe the SGS variability. We also incorporate a diagnostic PBL height parameterization to represent the strong inversion above PBL. The goal of this study is to compare the simulation of the climatology from these three

Real-world evaluation of compliance and preference in Alzheimer’s disease treatment: an observational study in Taiwan 

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Lai TH

2016-03-01

Full Text Available Tzu-Hsien Lai,1,2,* Wen-Fu Wang,3,* Bak-Sau Yip,4 Yu-Wan Yang,5 Giia-Sheun Peng,6 Shih-Jei Tsai,7,8 Yi-Chu Liao,9 Ming-Chyi Pai10,111Section of Neurology, Department of Internal Medicine, Far Eastern Memorial Hospital, New Taipei, 2Department of Neurology, National Yang-Ming University School of Medicine, Taipei, 3Department of Neurology, Changhua Christian Hospital, Changhua, 4Department of Neurology, National Taiwan University Hospital Hsin-Chu Branch, Hsinchu, 5Department of Neurology, China Medical University Hospital, Taichung, 6Department of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei, 7Department of Neurology, Chung Shan Medical University Hospital, Taichung, 8School of Medicine, Chung Shan Medical University, Taichung, 9Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, 10Division of Behavioral Neurology, Department of Neurology, 11Alzheimer’s Disease Research Center, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan City, Taiwan *These authors contributed equally to this workPurpose: Among the medications approved for Alzheimer’s disease (AD, rivastigmine is the only one available as transdermal patch. The aim of this study was to evaluate compliance and caregivers’ preference with oral and transdermal (rivastigmine monotherapy in patients with mild-to-moderate AD from Taiwan.Methods: Real-world Evaluation of Compliance And Preference in Alzheimer’s disease treatment (RECAP in Taiwan was a prospective, noninterventional, observational study with a 24-week (±8 weeks observational period for each participant. Eligible patients were grouped into one of the two treatment cohorts based on the baseline AD therapy: oral (donepezil, galantamine, rivastigmine, or memantine or transdermal (rivastigmine patch. The primary end points were caregiver preference and caregiver assessment of patients’ compliance to

Discurso del Académico Efraím Otero Ruiz, Presidente de la Sociedad Colombiana de Historia de la Medicina En la Recepción como Miembro Honorario del Dr. Egón Lichtenberger.

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Efraim Otero Ruiz

1998-12-01

Full Text Available

Bogotá, Mayo 15 de 1997

Señores Académicos, señoras, señores :

Retornamos antes de ocho días a esta alta tribuna del pensamiento académico, esta vez para acoger y exaltar como Académico Honorario al Profesor Dr. Egon Lichtenberger. En él consagramos no solamente a la Anatomía Patológica como especialidad, ausente muchos lustros de este recinto bogotano, desde la época de su numerario y posterior Presidente Dr. Juan Pablo Llinás, sino especialmente a la persona que con su dedicación, su enseñanza y su ejemplo ha servido para darle la categoría que corresponde a esta rama del saber médico, formando generaciones de nuevos patólogos que han extendido su conocimiento por todo lo largo y ancho de nuestra accidentada geografía.

Para reconocer la dimensión exacta de sus contribuciones, habría que mirar en qué estado se encontraba la anatomía patológica en Colombia al finalizar la década de los años cuarentas cuando Egon se gradúa de la Universidad Nacional, en 1947, con una tesis calificada como meritoria. Hasta la época de la lla. Guerra Mundial toda nuestra enseñanza anatomopatológica tomaba sus raíces en Francia, directamente derivada de Bichat y de Cruveilhier y admirablemente suplementada por los textos de anatomía descriptiva de Testut – Latarjet, que todo estudiante debía memorizar en dos años de agobiador ejercicio mnemotécnico. Allí, desde los bancos de disección anatómica, se barruntaban las variaciones de lo normal a lo patológico, que simultámeamente y a partir del segundo año de carrera se entrelazaban con las preparaciones histopatológicas.

Sin embargo, a pesar de que la escuela fisiopatológica se había originado en la Francia de mediados del ochocientos con Claude Bernard y sus seguidores, la anatomopatológia seguía teniendo la misma rigidez descriptiva de los anatomistas clásicos, sin que tratara de orientarse al estudiante, las más de las veces, hacia las

Diameter effect on critical heat flux

International Nuclear Information System (INIS)

Tanase, A.; Cheng, S.C.; Groeneveld, D.C.; Shan, J.Q.

2009-01-01

The critical heat flux look-up table (CHF LUT) is widely used to predict CHF for various applications, including design and safety analysis of nuclear reactors. Using the CHF LUT for round tubes having inside diameters different from the reference 8 mm involves conversion of CHF to 8 mm. Different authors [Becker, K.M., 1965. An Analytical and Experimental Study of Burnout Conditions in Vertical Round Ducts, Aktiebolaget Atomenergie Report AE 177, Sweden; Boltenko, E.A., et al., 1989. Effect of tube diameter on CHF at various two phase flow regimes, Report IPE-1989; Biasi, L., Clerici, G.C., Garriba, S., Sala, R., Tozzi, A., 1967. Studies on Burnout, Part 3, Energia Nucleare, vol. 14, pp. 530-536; Groeneveld, D.C., Cheng, S.C., Doan, T., 1986. AECL-UO critical heat flux look-up table. Heat Transfer Eng., 7, 46-62; Groeneveld et al., 1996; Hall, D.D., Mudawar, I., 2000. Critical heat flux for water flow in tubes - II subcooled CHF correlations. Int. J. Heat Mass Transfer, 43, 2605-2640; Wong, W.C., 1996. Effect of tube diameter on critical heat flux, MaSC dissertation, Ottawa Carleton Institute for Mechanical and Aeronautical Engineering, University of Ottawa] have proposed several types of correlations or factors to describe the diameter effect on CHF. The present work describes the derivation of new diameter correction factor and compares it with several existing prediction methods

Temporary endoscopic metallic stent for idiopathic esophageal achalasia.

Science.gov (United States)

Coppola, Franco; Gaia, Silvia; Rolle, Emanuela; Recchia, Serafino

2014-02-01

Idiopathic achalasia is a motor disorder of the esophagus of unknown etiology caused by loss of motor neurons determining an altered motility. It may determine severe symptoms such as progressive dysphagia, regurgitations, and pulmonary aspirations. Many therapeutic options may be offered to patients with achalasia, from surgery to endoscopic treatments such as pneumatic dilation, botulinum injection, peroral endoscopic myotomy, or endoscopic stenting. Recently, temporary placement of a stent was proposed by Cheng as therapy for achalasia disorders, whereas no Western authors have dealt with it up to date. The present study reports our preliminary experience in 7 patients with achalasia treated with a temporary stent. Partially covered self-expanding metallic stents (Micro-Tech, Nanjin, China) 80 mm long and 30 mm wide were placed under fluoroscopic control and removed after 6 days. Clinical follow-up was scheduled to check endoscopic success, symptoms release, and complications. The placement and the removal of the stents were obtained in all patients without complications. Mean clinical follow-up was 19 months. Five out of 7 patients referred total symptoms release and 2 experienced significant improvement of dysphagia. The procedure was not time consuming and was safe; no mild or severe complications were registered. In conclusion, our results may suggest a possible safe and effective endoscopic alternative treatment in patients with achalasia; however, further larger studies are necessary to confirm these promising, but very preliminary, data.

Andrographolide inhibits hypoxia-inducible factor-1 through phosphatidylinositol 3-kinase/AKT pathway and suppresses breast cancer growth

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Li J

2015-02-01

Full Text Available Jie Li,1 Chao Zhang,1 Hongchuan Jiang,1 Jiao Cheng21Department of General Surgery, 2Department of Gynaecology and Obstetrics, Beijing Chao-Yang Hospital, Beijing, People’s Republic of ChinaAbstract: Hypoxia-inducible factor-1 (HIF-1 is a master regulator of the transcriptional response to hypoxia. HIF-1α is one of the most compelling anticancer targets. Andrographolide (Andro was newly identified to inhibit HIF-1 in T47D cells (a half maximal effective concentration [EC50] of 1.03×10-7 mol/L, by a dual-luciferase reporter assay. It suppressed HIF-1α protein and gene accumulation, which was dependent on the inhibition of upstream phosphatidylinositol 3-kinase (PI3K/AKT pathway. It also abrogated the expression of HIF-1 target vascular endothelial growth factor (VEGF gene and protein. Further, Andro inhibited T47D and MDA-MB-231 cell proliferation and colony formation. In addition, it exhibited significant in vivo efficacy and antitumor potential against the MDA-MB-231 xenograft in nude mice. In conclusion, these results highlighted the potential effects of Andro, which inhibits HIF-1, and hence may be developed as an antitumor agent for breast cancer therapy in future.Keywords: Andrographolide (Andro, HIF-1α, inhibit, breast cancer, hypoxia, PI3k/AKT/mTOR pathway

Hyaluronic acid-coated bovine serum albumin nanoparticles loaded with brucine as selective nanovectors for intra-articular injection

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Chen Z

2013-10-01

Full Text Available Zhipeng Chen,* Juan Chen,* Li Wu, Weidong Li, Jun Chen, Haibo Cheng, Jinhuo Pan, Baochang CaiDepartment of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, People's Republic of China*These authors contributed equally to this workObjective: To evaluate the potential of hyaluronic acid (HA-coated bovine serum albumin nanoparticles (BSANPs as a novel chondrocyte-targeting drug-delivery nanomedicine.Methods: The HA-BSANPs were characterized by dynamic light scattering, transmission electron microscopy, differential scanning calorimetry, and X-ray diffraction. Fluorescence imaging was used to visualize the distribution of nanoparticles after intra-articular injection. The chondrocyte-targeting efficiency and cellular uptake mechanism of HA-BSANPs were investigated using endocytic inhibitors.Results: HA-BSANPs were successfully prepared with HA coating the surface and amorphous drug in the core. Compared with BSANPs, HA-BSANPs exhibited improved uptake by chondrocytes through a receptor-mediated active uptake mechanism. The endocytosis process of BSANPs and HA-BSANPs involved clathrin-mediated endocytosis, caveolae-mediated endocytosis, and macropinocytosis. No apparent thickening or hyperplasia of the synovium was observed in either BSANPs or HA-BSANPs. The HA-BSANPs could reside in the articular cavity of rats for more than 14 days, which was significantly longer than BSANPs.Conclusion: HA-BSANPs are a promising carrier for articular-related diseases due to elongated articular residence and improved chondrocytic accumulation.Keywords: chondrocyte, intra-articular injection, hyaluronic acid, BSA, nanoparticles

Rescuing apoptotic neurons in Alzheimer’s disease using wheat germ agglutinin-conjugated and cardiolipin-conjugated liposomes with encapsulated nerve growth factor and curcumin

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Kuo YC

2015-04-01

Full Text Available Yung-Chih Kuo, Ching-Chun Lin Department of Chemical Engineering, National Chung Cheng University, Chia-Yi, Taiwan, Republic of China Abstract: Liposomes with cardiolipin (CL and wheat germ agglutinin (WGA were developed to permeate the blood–brain barrier and treat Alzheimer’s disease. WGA-conjugated and CL-incorporated liposomes (WGA-CL-liposomes were used to transport nerve growth factor (NGF and curcumin (CUR across a monolayer of human brain-microvascular endothelial cells regulated by human astrocytes and to protect SK-N-MC cells against apoptosis induced by ß-amyloid1–42 (Aß1–42 fibrils. An increase in the CL mole percentage in lipids increased the liposomal diameter, absolute zeta potential value, entrapment efficiency of NGF and CUR, release of NGF, biocompatibility, and viability of SK-N-MC cells with Aß1–42, but decreased the atomic ratio of nitrogen to phosphorus and release of CUR. In addition, an increase in the WGA concentration for grafting enhanced the liposomal diameter, atomic ratio of nitrogen to phosphorus, and permeability of NGF and CUR across the blood–brain barrier, but reduced the absolute zeta potential value and biocompatibility. WGA-CL-liposomes carrying NGF and CUR could be promising colloidal delivery carriers for future clinical application in targeting the blood–brain barrier and inhibiting neurotoxicity. Keywords: Alzheimer’s disease, nerve growth factor, curcumin, wheat germ agglutinin, cardiolipin, liposome

Major ocular trauma in Taiwan: 2002-2004 versus 2012-2014.

Science.gov (United States)

Chang, Yi-Sheng; Teng, Yu-Ti; Huang, Yi-Hsun; Liu, Mei-Ling; Hung, Jia-Horung; Hsu, Sheng-Min; Huang, Fu-Chin; Shih, Min-Hsiu; Chen, Wan-Ju; Lai, Chun-Chieh; Hsiao, Shu-Fang; Wang, Shih-Hao; Tseng, Sung-Huei

2018-05-04

We investigated the temporal changes in major eye injuries in Taiwan by reviewing the medical records of all patients with ocular trauma hospitalized at the National Cheng Kung University Hospital during 2002-2004 and 2012-2014. A total of 169 eyes (161 patients) during 2002-2004 and 121 eyes (120 patients) during 2012-2014 were enrolled (mean ± SD age: 41.9 ± 20.8 years in 2002-2004, and 51.8 ± 19.3 years in 2012-2014). Males accounted for ~75% of patients. The most frequent injury-causing object was metallic material (~24%), and blunt traumas were most frequently attributable to traffic accidents and falls. The most common locations of injuries for males and females were the workplace and home, respectively. Open-globe injuries occurred in ~70% of eyes, requiring primary repair, cataract extraction, and/or intraocular lens implantation. The frequencies of fall injury, lacrimal system laceration, lens injury, corneal/scleral foreign bodies, and use of intracameral antibiotics increased from 2002-2004 to 2012-2014, while those of closed-globe injury, vitreous haemorrhage, optic nerve injury, and medical treatment decreased. The final visual acuity remained poor (≤20/200) in >1/3 of injured eyes. Despite therapeutic advancements, major eye injuries still pose a high risk for poor visual outcome.

The fourth dimension: A motoric perspective on the anxiety-performance relationship.

Science.gov (United States)

Carson, Howie J; Collins, Dave

2016-01-01

This article focuses on raising concern that anxiety-performance relationship theory has insufficiently catered for motoric issues during, primarily, closed and self-paced skill execution (e.g., long jump and javelin throw). Following a review of current theory, we address the under-consideration of motoric issues by extending the three-dimensional model put forward by Cheng, Hardy, and Markland (2009) ('Toward a three-dimensional conceptualization of performance anxiety: Rationale and initial measurement development, Psychology of Sport and Exercise , 10 , 271-278). This fourth dimension, termed skill establishment , comprises the level and consistency of movement automaticity together with a performer's confidence in this specific process, as providing a degree of robustness against negative anxiety effects. To exemplify this motoric influence, we then offer insight regarding current theories' misrepresentation that a self-focus of attention toward an already well-learned skill always leads to a negative performance effect. In doing so, we draw upon applied literature to distinguish between positive and negative self-foci and suggest that on what and how a performer directs their attention is crucial to the interaction with skill establishment and, therefore, performance. Finally, implications for skill acquisition research are provided. Accordingly, we suggest a positive potential flow from applied/translational to fundamental/theory-generating research in sport which can serve to freshen and usefully redirect investigation into this long-considered but still insufficiently understood concept.

Optical supervised filtering technique based on Hopfield neural network

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Bal, Abdullah

2004-11-01

Hopfield neural network is commonly preferred for optimization problems. In image segmentation, conventional Hopfield neural networks (HNN) are formulated as a cost-function-minimization problem to perform gray level thresholding on the image histogram or the pixels' gray levels arranged in a one-dimensional array [R. Sammouda, N. Niki, H. Nishitani, Pattern Rec. 30 (1997) 921-927; K.S. Cheng, J.S. Lin, C.W. Mao, IEEE Trans. Med. Imag. 15 (1996) 560-567; C. Chang, P. Chung, Image and Vision comp. 19 (2001) 669-678]. In this paper, a new high speed supervised filtering technique is proposed for image feature extraction and enhancement problems by modifying the conventional HNN. The essential improvement in this technique is to use 2D convolution operation instead of weight-matrix multiplication. Thereby, neural network based a new filtering technique has been obtained that is required just 3 × 3 sized filter mask matrix instead of large size weight coefficient matrix. Optical implementation of the proposed filtering technique is executed easily using the joint transform correlator. The requirement of non-negative data for optical implementation is provided by bias technique to convert the bipolar data to non-negative data. Simulation results of the proposed optical supervised filtering technique are reported for various feature extraction problems such as edge detection, corner detection, horizontal and vertical line extraction, and fingerprint enhancement.

Development of MATRA-LMR code α-version for LMR subchannel analysis

International Nuclear Information System (INIS)

Kim, Won Seok; Kim, Young Gyun; Kim, Young Gin

1998-05-01

Since the sodium boiling point is very high, maximum cladding and pin temperature are used for design limit condition in sodium cooled liquid metal reactor. It is necessary to predict accurately the core temperature distribution to increase the sodium coolant efficiency. Based on the MATRA code, which is developed for PWR analysis, MATRA-LMR is being developed for LMR. The major modification are as follows : A) The sodium properties table is implemented as subprogram in the code. B) Heat transfer coefficients are changed for LMR C) The pressure drop correlations are changed for more accurate calculations, which are Novendstern, Chiu-Rohsenow-Todreas, and Cheng-Todreas correlations. To assess the development status of MATRA-LMR code, calculations have been performed for ORNL 19 pin and EBR-II 61 pin tests. MATRA-LMR calculation results are also compared with the results obtained by the ALTHEN code, which uses more simplied thermal hydraulic model. The MATRA-LMR predictions are found to agree well to the measured values. The differences in results between MATRA-LMR and SLTHEN have occurred because SLTHEN code uses the very simplied thermal-hydraulic model to reduce computing time. MATRA-LMR can be used only for single assembly analysis, but it is planned to extend for multi-assembly calculation. (author). 18 refs., 8 tabs., 14 figs

Gamma rays from pulsar outer gaps

International Nuclear Information System (INIS)

Chiang, J.; Romani, R.W.; Cheng Ho

1993-01-01

We describe a gamma ray pulsar code which computes the high energy photon emissivities from vacuum gaps in the outer magnetosphere, after the model outlined by Cheng, Ho and Ruderman (1986) and Ho (1989). Pair-production due to photon-photon interactions and radiation processes including curvature, synchrotron and inverse Compton processes are computed with an iterative scheme which converges to self-consistent photon and particle distributions for a sampling of locations in the outer magnetosphere. We follow the photons from these distributions as they propagate through the pulsar magnetosphere toward a distant observer. We include the effects of relativistic aberration, time-of-flight delays and reabsorption by photon-photon pair-production to determine an intensity map of the high energy pulsar emission on the sky. Using data from radio and optical observations to constrain the geometry of the magnetosphere as well as the possible observer viewing angles, we derive light curves and phase dependent spectra which can be directly compared to data from the Compton Observatory. Observations for Crab, Vela and the recently identified gamma ray pulsars Geminga, PSR1706-44 aNd PSR 1509-58 will provide important tests of our model calculations, help us to improve our picture of the relevant physics at work in pulsar magnetospheres and allow us to comment on the implications for future pulsar discoveries

RETRACTED: Growth behavior and microstructure evolution of ZnO nanorods grown on Si in aqueous solution

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Liou, Sz-Chian; Hsiao, Chi-Sheng; Chen, San-Yuan

2005-02-01

This article has been retracted: please see Elsevier Policy on Article Withdrawal. This article has been retracted at the request of the Editor-in-Chief. Two papers published in the Journal of Crystal Growth are being retracted due to a case of misrepresentation and reuse of data. A reader of the Journal has brought to our attention the reuse of data within two published papers: Growth behavior and microstructure evolution of ZnO nanorods grown on Si in aqueous solution, Sz-Chian Liou, Chi-Sheng Hsiao, San-Yuan Chen, Journal of Crystal Growth 274 (2005) 438-446. Nucleation and growth behavior of well-aligned ZnO nanorods on organic substrates in aqueous solutions, Chin-Ching Lin, San-Yuan Chen, and Syh-Yuh Cheng, Journal of Crystal Growth 283 (2005) 141-146. In these papers the same transmission electron micrograph was used to describe two different experimental situations and results bringing into question the content of these papers. The reuse of data without proper attribution is not acceptable within the scientific publishing community. In the present case, this is compounded by the attribution of the micrograph to a different experimental situation and drawing, as a result, new conclusions from data obtained from different samples. Such behavior undermines the integrity of the scientific publishing endeavor and is not acceptable. The authors are responsible for the content of their papers.

The Initial Results from the LITN of the FORMOSAT-3 TBB Program

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Tung Yuan Hsiao

2009-01-01

Full Text Available Beginning in 2006, four ground stations located at Chung-Li (25.136°N, 121.539°E, TasoTun (23.981°N, 120.697°E, CheCheng (22.725°N, 120.544°E, and tropical Itu Aba Island (10.06°N, 114.350°E were set up to receive beacon signals from six FORMOSAT-3/COSMIC (Bernhardt et al. 2000 and other NNSS-like satellites. By applying differential Doppler technique on three quadrature components of the three-band beacon signals, we were able to obtain total electric contents (TEC values and scintillation along the radio path through the ionosphere. Such measurements can be used to derive regional ionospheric irregularity and tomography. In this paper, we have confirmed the power patterns contributed from the transmitting antennas on board FS3/COSMIC and the ground-based receiving antennas. The multiplicative algebraic reconstruction technique (MART algorithm has also been implemented to reconstruct ionospheric tomography images. Observations of the diurnal variations and the dynamics of equatorial anomaly showed that the equatorial anomaly appeared at 0800 LT, and then subsequently moved toward the Earth's poles. The north crest was strongest at ~1300 LT and its core was located at about 10°N of the magnetic latitude (~20°N geographic latitude. Afterwards, the crest moved toward the equator after sunset and disappeared after midnight.

Consumption of fa cai Nostoc soup: a potential for BMAA exposure from Nostoc cyanobacteria in China?

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Roney, Britton R; Renhui, Li; Banack, Sandra Anne; Murch, Susan; Honegger, Rosmarie; Cox, Paul Alan

2009-01-01

Grown in arid regions of western China the cyanobacterium Nostoc flagelliforme--called fa cai in Mandarin and fat choy in Cantonese--is wild-harvested and used to make soup consumed during New Year's celebrations. High prices, up to $125 USD/kg, led to overharvesting in Inner Mongolia, Ningxia, Gansu, Qinghai, and Xinjiang. Degradation of arid ecosystems, desertification, and conflicts between Nostoc harvesters and Mongol herdsmen concerned the Chinese environmental authorities, leading to a government ban of Nostoc commerce. This ban stimulated increased marketing of a substitute made from starch. We analysed samples purchased throughout China as well as in Chinese markets in the United States and the United Kingdom. Some were counterfeits consisting of dyed starch noodles. A few samples from California contained Nostoc flagelliforme but were adulterated with starch noodles. Other samples, including those from the United Kingdom, consisted of pure Nostoc flagelliforme. A recent survey of markets in Cheng Du showed no real Nostoc flagelliforme to be marketed. Real and artificial fa cai differ in the presence of beta-N-methylamino-L-alanine (BMAA). Given its status as a high-priced luxury food, the government ban on collection and marketing, and the replacement of real fa cai with starch substitutes consumed only on special occasions, it is anticipated that dietary exposure to BMAA from fa cai will be reduced in the future in China.

MHD Ballooning Instability in the Plasma Sheet

International Nuclear Information System (INIS)

Cheng, C.Z.; Zaharia, S.

2003-01-01

Based on the ideal-MHD model the stability of ballooning modes is investigated by employing realistic 3D magnetospheric equilibria, in particular for the substorm growth phase. Previous MHD ballooning stability calculations making use of approximations on the plasma compressibility can give rise to erroneous conclusions. Our results show that without making approximations on the plasma compressibility the MHD ballooning modes are unstable for the entire plasma sheet where beta (sub)eq is greater than or equal to 1, and the most unstable modes are located in the strong cross-tail current sheet region in the near-Earth plasma sheet, which maps to the initial brightening location of the breakup arc in the ionosphere. However, the MHD beq threshold is too low in comparison with observations by AMPTE/CCE at X = -(8 - 9)R(sub)E, which show that a low-frequency instability is excited only when beq increases over 50. The difficulty is mitigated by considering the kinetic effects of ion gyrorad ii and trapped electron dynamics, which can greatly increase the stabilizing effects of field line tension and thus enhance the beta(sub)eq threshold [Cheng and Lui, 1998]. The consequence is to reduce the equatorial region of the unstable ballooning modes to the strong cross-tail current sheet region where the free energy associated with the plasma pressure gradient and magnetic field curvature is maximum

Rapid authentication of different ages of tissue-cultured and wild Dendrobium huoshanense as well as wild Dendrobium henanense using FTIR and 2D-COS IR

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Chen, Nai-Dong; Chen, Nai-Fu; Li, Jun; Cao, Cai-Yun; Wang, Jin-Mei

2015-12-01

The accumulating of pharmaceutical chemicals in medicinal plants would greatly be affected by their ages and establishing a fast quality-identification method to evaluate the similarity of medicinal herbs at different cultivated ages is a critical step for assurance of quality and safety in the TCM industry. In this work, tri-step IR macro-fingerprinting and 2D-COS IR spectrum techniques combined with statistical pattern recognition were applied for discrimination and similarity evaluation of different ages of tissue-cultured and wild Dendrobium huoshanense C. Z. Tang et S. J. Cheng as well as Dendrobium henanense J.L.Lu et L.X Gao. Both tissue-cultured and wild D. huoshanense were easily differentiated from D. henanense by FTIR and SD-IR spectra, while it's quite difficult to discriminate different cultivated years of the three investigated Dendrobiums. In 2D-COS IR spectra, 1-5 auto-peaks with different indensity and positions were located in the region 1160-1030 cm-1 of the twelve Dendrobium samples and thus could be used to identify Dendrobium samples at different ages. Principle component analysis (PCA) of synchronous 2D-COS data showed that the twelve samples were effectively identified and evaluated. The results indicated that the tri-step infrared macro-fingerprinting combined with PCA method was suitable to differentiate the cultivated ages of Dendrobiums with species and orgins rapidly and nondestructively.

Domain-specific reasoning: social contracts, cheating, and perspective change.

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Gigerenzer, G; Hug, K

1992-05-01

What counts as human rationality: reasoning processes that embody content-independent formal theories, such as propositional logic, or reasoning processes that are well designed for solving important adaptive problems? Most theories of human reasoning have been based on content-independent formal rationality, whereas adaptive reasoning, ecological or evolutionary, has been little explored. We elaborate and test an evolutionary approach. Cosmides' (1989) social contract theory, using the Wason selection task. In the first part, we disentangle the theoretical concept of a "social contract" from that of a "cheater-detection algorithm". We demonstrate that the fact that a rule is perceived as a social contract--or a conditional permission or obligation, as Cheng and Holyoak (1985) proposed--is not sufficient to elicit Cosmides' striking results, which we replicated. The crucial issue is not semantic (the meaning of the rule), but pragmatic: whether a person is cued into the perspective of a party who can be cheated. In the second part, we distinguish between social contracts with bilateral and unilateral cheating options. Perspective change in contracts with bilateral cheating options turns P & not-Q responses into not-P & Q responses. The results strongly support social contract theory, contradict availability theory, and cannot be accounted for by pragmatic reasoning schema theory, which lacks the pragmatic concepts of perspectives and cheating detection.

Rare clinical experiences for surgical treatment of melanoma with osseous metastases in Taiwan

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Yang Rong-Sen

2007-07-01

Full Text Available Abstract Background Malignant melanoma occurs infrequently in Taiwan. Once it has progressed into osseous metastases, the prognosis is poor. There are no reported clinical experiences of surgical management in this area. Methods To improve our understanding of the rare clinical experiences, we retrospectively investigated clinical characteristics, radiological findings, treatment modalities, survival outcomes and prognoses of 11 Taiwanese patients with osseous metastasis of melanoma treated surgically at two national medical centers, National Taiwan University Hospital and National Cheng Kung University Hospital from January 1983 to December 2006. Results Six patients suffered from acral-lentiginous melanoma. Nine patients sustained multiple osseous metastases and most lesions were osteolytic. Nine patients also had sustained metastases to other organs including liver, lungs, lymph nodes, brain and spleen. Second malignancies including lung cancer, thyroid papillary carcinoma, renal cell carcinoma and cervical cancer co-existed in four patients. The interval from the initial diagnosis of melanoma to the clinical detection of osseous metastases varied from 0–37.8 months (mean 9.75 months. Metastatic melanoma was invariably fatal; the mean survival time from bone metastases to death was 5.67 months. Conclusion Due to the high morbidity and poor survival of Taiwanese patients with osseous metastases of melanoma, surgical treatment should be directed towards pain relief and the prevention of skeletal debilitation in order to maintain their quality of life.

Call for Papers and Announcement Joint International Conference of Industrial Engineering and Engineering Management (IE&EM'2002)And International Conference on Electronic Commerce Engineering (ICECE'2002)%“2002年工业工程与工程管理国际会议（IE&EM’2002）”暨“2002年电子商务工程国际会议（IceCE’2002）”征文通知

Institute of Scientific and Technical Information of China (English)

无

2002-01-01

Metropolitan University, UK Members: (in alphabetic order) Fukuda Shuichi (Japan) Ning Ruxin (China) Qi Ershi (China) Mitchell M. Tseng (HK) G. Doumeingts (France) Richard Harrison (UK) Jim Browne (Ireland) F.-L Krause (Germany) Lei Yuanzhong (NSFC, China) Li Ming (NSFC, China) Li Peigeng (China) Liu Fei (China) Lin Zhongqin(863/automation, China) Roddy MacLeod (UK) Chris McMahon (UK) Martin Moltrecht(Germany) Sun Jiaguang (863/automation, China) Tang Xiaoqing (China) Wang Ruigang (CMES, China) Wang Yingluo(China) Wen Yuping (Tsinghua, Taiwan) Xia Guoping (China) Yan Junqi (China) Organizing Committee Chairman: Zheng Li, Tsinghua University (China) Co-Chairmen: Kai Cheng (UK) Jiang Pingyu (China) Guoquan Huang (Hong Kong) Li Congdong (China) Members: (in alphabetic order) Richard Bateman (UK) Liu Dacheng (China) Pan P.Y. (UK) Jeremy Toussaint (UK) Wu Shu(China) Yu Ming (China)Secretariat: General Secretary: Yu Ming (China) Members: Cai Linning (China) Jiang Zhibin (China) Yi Shuping (China) Zeng Haiming(China) Zhang Wei (China) Zhao Huanmai (China) Submissions Submitted papers should be in English and will be accepted in two types: regular papers limited to 8 pages, after that S|100 per additional page, but no more than 12 pages, and short papers limited to 4 pages. Papers submitted should be in MS Word or its compressed (zip) form. The format of submitted papers is: A4, 20mm margin at left side and 28mm at right side; double column, each 81mm wide with a 8mm space between columns; 18pt Times New Roman for the title; 10.5pt Times New Roman for text, author(s), affiliation(s), mailing address(es) and e-mail address(es); the space between lines is single space and the space between words is standard. On the first page, the top 50mm of both columns should be reserved for the title, author(s), affiliation(s), mailing address(es) and email address(es), which should be centered across both columns; on the second and subsequent pages, the text or illustrations should begin at the top

PREFACE: Preface

Science.gov (United States)

Ye, Chaohui; Wang, Zhong Lin; Zhou, Bingkun

2011-02-01

National Laboratory for Optoelectronics (China)Junqiang Sun, Wuhan National Laboratory for Optoelectronics (China) 4. OPTOELECTRONIC SENSING AND IMAGING (OSI)Editors:Kecheng Yang, Wuhan National Laboratory for Optoelectronics (China)Pengcheng Li, Wuhan National Laboratory for Optoelectronics (China) 5. SOLAR CELLS, SOLID-STATE LIGHTING AND INFORMATION DISPLAY TECHNOLOGIES (SSID)Editors:Hiroshi Amano, Meijo University (Japan)Yibing Cheng, Monash University (Australia)Jinzhong Yu, Institute of Semiconductor, CAS (China)Changqing Chen, Wuhan National Laboratory for Optoelectronics (China)Hongwei Han, Wuhan National Laboratory for Optoelectronics (China)Guoli Tu, Wuhan National Laboratory for Optoelectronics (China) 6. TERA-HERTZ SCIENCE AND TECHNOLOGY (THST)Editors:Jianquan Yao, Tianjin University (China)Shenggang Liu, University of Electronic Science and Technology of China (China)X C Zhang, Rensselaer Polytechnic Institute (USA)Jinsong Liu, Wuhan National Laboratory for Optoelectronics (China) International Advisory Committee:Yibing Cheng, Monash University (Australia)Stephen Z D Cheng, University of Akron (USA)Min Gu, Swinburne University of Technology (Australia)Andrew B Holmes, the University of Melbourne (Australia)Chinlon Lin, Bell Laboratory (retired, USA)Xun Li, McMaster University (Canada)Shenggang Liu, University of Electronic Science and Technology of China (China)Jesper Moerk, Technical University of Denmark (Denmark)Dennis L Matthews, University of California, Davis (USA)Jiacong Shen, Jilin University (China)Ping Shum, Nanyang Technological University (Singapore)Chester C T Shu, Chinese University of Hong Kong (China)Valery V Tuchin, Saratov State University (Russia)Bruce Tromberg, University of California/Irvine (USA)Peiheng Wu, University of Nanjing (China)Alan Willner, University of Southern California (USA)Lihong Wang, Washington University in St. Louis (USA)C P Wong, Georgia Institute of Technology (USA)Jianquan Yao, Tianjin University (China)Xi Zhang

El ejemplar del Geka seiso (1791 de la Colección Francisco Guerra por José Luis Gonzalo Sánchez-Molero

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Gonzalo Sánchez-Molero, José Luis

2010-01-01

Full Text Available Desde 2007 la Biblioteca Histórica Marqués de Valdecilla conserva un ejemplar del Geka seiso, un libro xilográfico japonés impreso en el siglo XVIII. Su título original chino es Waik'o Cheng Tsung, o Método ortodoxo de la cirugía, en español. Esta tratado médico fue escrito al inicio del siglo anterior por Chen Shih-kung, o Chen Shigong, (c. 1555-1636, y en 1791 fue editado de nuevo en Japón por el médico imperial Ogino Gengai (1737-1806. Este ejemplar complutense proviene de la colección de Francisco Guerra Pérez-Carral. En este artículo se estudian tres aspectos del Geka seiso, en un orden cronológico inverso. Primero, su adquisición por el doctor Guerra, quien lo compró en Miami (1990, procedente el volumen de la colección del doctor norteamericano Otto Orren Fisher. A continuación se analiza el contenido de esta obra, publicada por vez primera en 1611, en China. En ella su autor (Chen Shigong incluyó sus famosos preceptos profesionales y éticos: Los cinco mandamientos y las diez exigencias. Por último se estudian, por un lado, las circunstancias históricas de esta edición en 1791, relacionada probablemente con el proceso político de restauración de los estudios Chu Hsi, y por otro lado el proceso técnico de su impresión, realizado en Kyoto por Hayashi Gonbe, Hayashi Ihe y Takemura Kahe. Finalmente se describen y comentan algunas de las características materiales de este ejemplar del Geka seiso, para su mejor comprensión por un lector occidental.Since 2007, the Historical Library "Marqués de Valdecilla" preserves a copy of Geka seiso, a Japanese blockbook printed in the eighteenth century. Its original title Chinese is Waik'o Cheng Tsung, or Orthodox method of surgery, in English. This medical treatise was written at the beginning of the previous century by Chen Shih-kung, or Chen Shigong, (c. 1555-1636, and in 1791 was printed again in Japan by the imperial doctor Gengai Ogino (1737-1806. This complutense copy

Predictive factors warrant screening for obstructive sleep apnea in COPD: a Taiwan National Survey

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Hang LW

2016-03-01

Full Text Available Liang-Wen Hang,1,2 Jeng-Yuan Hsu,3 Chee-Jen Chang,4 Hao-Chien Wang,5,6 Shih-Lung Cheng,7,8 Ching-Hsiung Lin,9 Ming-Cheng Chan,3 Chin-Chou Wang,10 Diahn-Warng Perng,11 Chong-Jen Yu5,6 On behalf of the Taiwan COPD Consortium 1Department of Respiratory Therapy, College of Health Care, China Medical University, 2Sleep Medicine Center, Department of Pulmonary and Critical Care Medicine, China Medical University Hospital, 3Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, 4Biostatistical Center for Clinical Research, Chang Gung Memorial Hospital, Linkou Branch, Guishan Township, Taoyuan County, 5Department of Internal Medicine, National Taiwan University Hospital, 6Department of Internal Medicine, National Taiwan University, College of Medicine, Taipei, 7Department of Internal Medicine, Far Eastern Memorial Hospital, New Taipei City, 8Department of Chemical Engineering and Materials Science, Yuan Ze University, Chung-Li City, Taoyuan County, 9Division of Chest Medicine, Changhua Christian Hospital, Changhua City, Changhua County, 10Division of Pulmonary and Critical Care Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, 11Department of Chest Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, Republic of China Background and objectives: COPD and obstructive sleep apnea (OSA share similar pathological processes and cardiovascular sequelae. Coexisting OSA in COPD – “overlap syndrome” – has worse prognosis than either condition alone, and appropriate treatment improves survival. Our objectives were to ascertain the frequency at which COPD coexists with the risk of OSA in Taiwan and to compare the risk factors, COPD symptoms, and life quality metrics between COPD subgroups with versus without risk of OSA. Methods: We conducted a random cross-sectional national telephone survey of adults >40 years old in Taiwan. Participants fulfilling an epidemiological case definition of COPD completed a

Use of multiple attributes decision-making Technique for Order Preference by Similarity to Ideal Solution (TOPSIS for Ghare-Gheshlagh calcite in determination of optimum geochemical sampling sites

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Mansour Rezaei Azizi

2015-04-01

Full Text Available Introduction Several valuable calcite deposits are located in Ghare-Gheshlagh, south basin of Urmia Lake, NW Iran. Ghare-Gheshlagh area is situated in the northern part of tectono-sedimentary unit, forming NW part of Tertiary Sanandaj-Sirjan geological belt (Stocklin and Nabavi, 1972. The predominant rock types of the area include light color limestones (Qom Formation and Quaternary alluviums and underlined dolomite in depth (Eftekharnejhad, 1973. The thickness of these units varies between 10 cm and 6 meters and up to some hundred meters in length. In the present study, the effect of geochemical parameters responsible for precipitating calcite from the carbonate aqueous fluids is interpreted by the TOPSIS method to find the most preferable sampling sites and geochemical data. Materials and Methods A total of 20 samples were taken from a NE-SW trending profile including 15 calcites of fresh surface outcrops (5 samples per each colored calcite units in order to determine the nature of the rocks. The mineral assemblages were analyzed by optical methods in combination with XRD powder diffraction analysis. Major elements were determined by X-Ray Fluorescence Spectrometry (XRF, trace and rare earth elements were determined by Inductively Coupled Plasma Mass Spectrometry (ICP-MS in Geological Survey of Iran. Results The abundances of trace elements were normalized to the continental crust values (Taylor and McLennan, 1981. The green calcite revealed enrichment in Rb and Sr, while green and white calcite were enriched in U. The U enrichment in the green calcite indicates the reduction condition of deposition. Incompatible elements such as Ba, Th, Nb and P depleted in all calcites. Varying the Sr/Ba value between 3.18 and 5.21% indicates the continental deposition environment and non-magmatic waters as well (Cheng et al., 2013. The Sr2+ content of calcites varies from 123 to 427 ppm, indicates suitable condition for calcite precipitation. Eu anomalies

Measurements of phoretic velocities of aerosol particles in microgravity conditions

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Prodi, F.; Santachiara, G.; Travaini, S.; Vedernikov, A.; Dubois, F.; Minetti, C.; Legros, J. C.

2006-11-01

Measurements of thermo- and diffusio-phoretic velocities of aerosol particles (carnauba wax, paraffin and sodium chloride) were performed in microgravity conditions (Drop Tower facility, in Bremen, and Parabolic Flights, in Bordeaux). In the case of thermophoresis, a temperature gradient was obtained by heating the upper plate of the cell, while the lower one was maintained at environmental temperature. For diffusiophoresis, the water vapour gradient was obtained with sintered plates imbued with a water solution of MgCl 2 and distilled water, at the top and at the bottom of the cell, respectively. Aerosol particles were observed through a digital holographic velocimeter, a device allowing the determination of 3-D coordinates of particles from the observed volume. Particle trajectories and consequently particle velocities were reconstructed through the analysis of the sequence of particle positions. The experimental values of reduced thermophoretic velocities are between the theoretical values of Yamamoto and Ishihara [Yamamoto, K., Ishihara, Y., 1988. Thermophoresis of a spherical particle in a rarefied gas of a transition regime. Phys. Fluids. 31, 3618-3624] and Talbot et al. [Talbot, L., Cheng, R.K., Schefer, R.W., Willis, D.R., 1980. Thermophoresis of particles in a heated boundary layer. J. Fluid Mech. 101, 737-758], and do not show a clear dependence on the thermal conductivity of the aerosol. The existence of negative thermophoresis is not confirmed in our experiments. Concerning diffusiophoretic experiments, the results obtained show a small increase of reduced diffusiophoretic velocity with the Knudsen number.

Development of an Indoor Location Based Service Test Bed and Geographic Information System with a Wireless Sensor Network

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Jan, Shau-Shiun; Hsu, Li-Ta; Tsai, Wen-Ming

2010-01-01

In order to provide the seamless navigation and positioning services for indoor environments, an indoor location based service (LBS) test bed is developed to integrate the indoor positioning system and the indoor three-dimensional (3D) geographic information system (GIS). A wireless sensor network (WSN) is used in the developed indoor positioning system. Considering the power consumption, in this paper the ZigBee radio is used as the wireless protocol, and the received signal strength (RSS) fingerprinting positioning method is applied as the primary indoor positioning algorithm. The matching processes of the user location include the nearest neighbor (NN) algorithm, the K-weighted nearest neighbors (KWNN) algorithm, and the probabilistic approach. To enhance the positioning accuracy for the dynamic user, the particle filter is used to improve the positioning performance. As part of this research, a 3D indoor GIS is developed to be used with the indoor positioning system. This involved using the computer-aided design (CAD) software and the virtual reality markup language (VRML) to implement a prototype indoor LBS test bed. Thus, a rapid and practical procedure for constructing a 3D indoor GIS is proposed, and this GIS is easy to update and maintenance for users. The building of the Department of Aeronautics and Astronautics at National Cheng Kung University in Taiwan is used as an example to assess the performance of various algorithms for the indoor positioning system. PMID:22319282

Anti-EGFR-iRGD recombinant protein conjugated silk fibroin nanoparticles for enhanced tumor targeting and antitumor efficiency

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Bian X

2016-05-01

Full Text Available Xinyu Bian,* Puyuan Wu,* Huizi Sha, Hanqing Qian, Qing Wang, Lei Cheng, Yang Yang, Mi Yang, Baorui LiuComprehensive Cancer Center of Drum-Tower Hospital, Medical School of Nanjing University, Clinical Cancer Institute of Nanjing University, Nanjing, People’s Republic of China*These authors contributed equally to this workAbstract: In this study, we report a novel kind of targeting with paclitaxel (PTX-loaded silk fibroin nanoparticles conjugated with iRGD–EGFR nanobody recombinant protein (anti-EGFR-iRGD. The new nanoparticles (called A-PTX-SF-NPs were prepared using the carbodiimide-mediated coupling procedure and their characteristics were evaluated. The cellular cytotoxicity and cellular uptake of A-PTX-SF-NPs were also investigated. The results in vivo suggested that NPs conjugated with the recombinant protein exhibited more targeting and anti-neoplastic property in cells with high EGFR expression. In the in vivo antitumor efficacy assay, the A-PTX-SF-NPs group showed slower tumor growth and smaller tumor volumes than PTX-SF-NPs in a HeLa xenograft mouse model. A real-time near-infrared fluorescence imaging study showed that A-PTX-SF-NPs could target the tumor more effectively. These results suggest that the anticancer activity and tumor targeting of A-PTX-SF-NPs were superior to those of PTX-SF-NPs and may have the potential to be used for targeted delivery for tumor therapies. Keywords: EGFR, nanobody, iRGD, recombinant protein, targeting drug carriers, antitumor efficiency

Improved thermal lattice Boltzmann model for simulation of liquid-vapor phase change

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Li, Qing; Zhou, P.; Yan, H. J.

2017-12-01

In this paper, an improved thermal lattice Boltzmann (LB) model is proposed for simulating liquid-vapor phase change, which is aimed at improving an existing thermal LB model for liquid-vapor phase change [S. Gong and P. Cheng, Int. J. Heat Mass Transfer 55, 4923 (2012), 10.1016/j.ijheatmasstransfer.2012.04.037]. First, we emphasize that the replacement of ∇ .(λ ∇ T ) /∇.(λ ∇ T ) ρ cV ρ cV with ∇ .(χ ∇ T ) is an inappropriate treatment for diffuse interface modeling of liquid-vapor phase change. Furthermore, the error terms ∂t 0(T v ) +∇ .(T vv ) , which exist in the macroscopic temperature equation recovered from the previous model, are eliminated in the present model through a way that is consistent with the philosophy of the LB method. Moreover, the discrete effect of the source term is also eliminated in the present model. Numerical simulations are performed for droplet evaporation and bubble nucleation to validate the capability of the model for simulating liquid-vapor phase change. It is shown that the numerical results of the improved model agree well with those of a finite-difference scheme. Meanwhile, it is found that the replacement of ∇ .(λ ∇ T ) /∇ .(λ ∇ T ) ρ cV ρ cV with ∇ .(χ ∇ T ) leads to significant numerical errors and the error terms in the recovered macroscopic temperature equation also result in considerable errors.

Drug-like density: a method of quantifying the "bindability" of a protein target based on a very large set of pockets and drug-like ligands from the Protein Data Bank.

Science.gov (United States)

Sheridan, Robert P; Maiorov, Vladimir N; Holloway, M Katharine; Cornell, Wendy D; Gao, Ying-Duo

2010-11-22

One approach to estimating the "chemical tractability" of a candidate protein target where we know the atomic resolution structure is to examine the physical properties of potential binding sites. A number of other workers have addressed this issue. We characterize ~290,000 "pockets" from ~42,000 protein crystal structures in terms of a three parameter "pocket space": volume, buriedness, and hydrophobicity. A metric DLID (drug-like density) measures how likely a pocket is to bind a drug-like molecule. This is calculated from the count of other pockets in its local neighborhood in pocket space that contain drug-like cocrystallized ligands and the count of total pockets in the neighborhood. Surprisingly, despite being defined locally, a global trend in DLID can be predicted by a simple linear regression on log(volume), buriedness, and hydrophobicity. Two levels of simplification are necessary to relate the DLID of individual pockets to "targets": taking the best DLID per Protein Data Bank (PDB) entry (because any given crystal structure can have many pockets), and taking the median DLID over all PDB entries for the same target (because different crystal structures of the same protein can vary because of artifacts and real conformational changes). We can show that median DLIDs for targets that are detectably homologous in sequence are reasonably similar and that median DLIDs correlate with the "druggability" estimate of Cheng et al. (Nature Biotechnology 2007, 25, 71-75).

Phenotypic H-Antigen Typing by Mass Spectrometry Combined with Genetic Typing of H Antigens, O Antigens, and Toxins by Whole-Genome Sequencing Enhances Identification of Escherichia coli Isolates.

Science.gov (United States)

Cheng, Keding; Chui, Huixia; Domish, Larissa; Sloan, Angela; Hernandez, Drexler; McCorrister, Stuart; Robinson, Alyssia; Walker, Matthew; Peterson, Lorea A M; Majcher, Miles; Ratnam, Sam; Haldane, David J M; Bekal, Sadjia; Wylie, John; Chui, Linda; Tyler, Shaun; Xu, Bianli; Reimer, Aleisha; Nadon, Celine; Knox, J David; Wang, Gehua

2016-08-01

Mass spectrometry-based phenotypic H-antigen typing (MS-H) combined with whole-genome-sequencing-based genetic identification of H antigens, O antigens, and toxins (WGS-HOT) was used to type 60 clinical Escherichia coli isolates, 43 of which were previously identified as nonmotile, H type undetermined, or O rough by serotyping or having shown discordant MS-H and serotyping results. Whole-genome sequencing confirmed that MS-H was able to provide more accurate data regarding H antigen expression than serotyping. Further, enhanced and more confident O antigen identification resulted from gene cluster based typing in combination with conventional typing based on the gene pair comprising wzx and wzy and that comprising wzm and wzt The O antigen was identified in 94.6% of the isolates when the two genetic O typing approaches (gene pair and gene cluster) were used in conjunction, in comparison to 78.6% when the gene pair database was used alone. In addition, 98.2% of the isolates showed the existence of genes for various toxins and/or virulence factors, among which verotoxins (Shiga toxin 1 and/or Shiga toxin 2) were 100% concordant with conventional PCR based testing results. With more applications of mass spectrometry and whole-genome sequencing in clinical microbiology laboratories, this combined phenotypic and genetic typing platform (MS-H plus WGS-HOT) should be ideal for pathogenic E. coli typing. Copyright © 2016 Cheng et al.

The fourth dimension: A motoric perspective on the anxiety–performance relationship

Science.gov (United States)

Carson, Howie J.; Collins, Dave

2016-01-01

ABSTRACT This article focuses on raising concern that anxiety–performance relationship theory has insufficiently catered for motoric issues during, primarily, closed and self-paced skill execution (e.g., long jump and javelin throw). Following a review of current theory, we address the under-consideration of motoric issues by extending the three-dimensional model put forward by Cheng, Hardy, and Markland (2009) (‘Toward a three-dimensional conceptualization of performance anxiety: Rationale and initial measurement development, Psychology of Sport and Exercise, 10, 271–278). This fourth dimension, termed skill establishment, comprises the level and consistency of movement automaticity together with a performer's confidence in this specific process, as providing a degree of robustness against negative anxiety effects. To exemplify this motoric influence, we then offer insight regarding current theories’ misrepresentation that a self-focus of attention toward an already well-learned skill always leads to a negative performance effect. In doing so, we draw upon applied literature to distinguish between positive and negative self-foci and suggest that on what and how a performer directs their attention is crucial to the interaction with skill establishment and, therefore, performance. Finally, implications for skill acquisition research are provided. Accordingly, we suggest a positive potential flow from applied/translational to fundamental/theory-generating research in sport which can serve to freshen and usefully redirect investigation into this long-considered but still insufficiently understood concept. PMID:26692896

Enhancing the in vivo transdermal delivery of gold nanoparticles using poly(ethylene glycol and its oleylamine conjugate

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Hsiao PF

2016-05-01

Full Text Available Pa Fan Hsiao,1–3 Sydney Peng,4 Ting-Cheng Tang,4 Shuian-Yin Lin,5 Hsieh-Chih Tsai4 1Department of Dermatology, Mackay Memorial Hospital, 2Mackay Medicine, Nursing and Management College, 3Mackay Medical College, New Taipei City, 4Graduate Institute of Applied Science and Technology, National Taiwan University of Science and Technology, Taipei, 5National Applied Research Laboratories, Instrument Technology Research Center, Hsinchu, Taiwan Abstract: In this study, we investigated the effect of (ethylene glycol (PEG and PEG–oleylamine (OAm functionalization on the skin permeation property of gold nanoparticles (GNS in vivo. Chemisorption of polymers onto GNS was verified by a red shift in the ultraviolet–visible spectrum as well as by a change in the nanoparticle surface charge. The physicochemical properties of pristine and functionalized nanoparticles were analyzed by ultraviolet–visible spectroscopy, zeta potential analyzer, and transmission electron microscopy. Transmission electron microscopy revealed that the interparticle distance between nanoparticles increased after GNS functionalization. Comparing the skin permeation profile of pristine and functionalized GNS, the follicular deposition of GNS increased twofold after PEG–OAm functionalization. Moreover, PEG- and PEG–OAm-functionalized nanoparticles were able to overcome the skin barrier and deposit in the deeper subcutaneous adipose tissue. These findings demonstrate the potential of PEG- and PEG–OAm-functionalized GNS in serving a multitude of applications in transdermal pharmaceuticals. Keywords: skin penetration, amphiphilic copolymer, gold nanoparticle, oleylamine, poly(ethylene glycol

Development of an Indoor Location Based Service Test Bed and Geographic Information System with a Wireless Sensor Network

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Shau-Shiun Jan

2010-03-01

Full Text Available In order to provide the seamless navigation and positioning services for indoor environments, an indoor location based service (LBS test bed is developed to integrate the indoor positioning system and the indoor three-dimensional (3D geographic information system (GIS. A wireless sensor network (WSN is used in the developed indoor positioning system. Considering the power consumption, in this paper the ZigBee radio is used as the wireless protocol, and the received signal strength (RSS fingerprinting positioning method is applied as the primary indoor positioning algorithm. The matching processes of the user location include the nearest neighbor (NN algorithm, the K-weighted nearest neighbors (KWNN algorithm, and the probabilistic approach. To enhance the positioning accuracy for the dynamic user, the particle filter is used to improve the positioning performance. As part of this research, a 3D indoor GIS is developed to be used with the indoor positioning system. This involved using the computer-aided design (CAD software and the virtual reality markup language (VRML to implement a prototype indoor LBS test bed. Thus, a rapid and practical procedure for constructing a 3D indoor GIS is proposed, and this GIS is easy to update and maintenance for users. The building of the Department of Aeronautics and Astronautics at National Cheng Kung University in Taiwan is used as an example to assess the performance of various algorithms for the indoor positioning system.

An improved lattice Boltzmann scheme for multiphase fluid with multi-range interactions

Energy Technology Data Exchange (ETDEWEB)

Maquignon, Nicolas; Duchateau, Julien; Roussel, Gilles; Rousselle, François; Renaud, Christophe [Laboratoire Informatique Signal et Image de la Côte d' Opale, 50 rue Ferdinand Buisson, 62100 Calais (France); Université du Littoral Côte d' Opale, 1 place de l' Yser, 59140, Dunkerque (France); Association INNOCOLD, MREI 1, 145 (France)

2014-10-06

Modeling of fluids with liquid to gas phase transition has become important for understanding many environmental or industrial processes. Such simulations need new techniques, because traditional solvers are often limited. The Lattice Boltzmann Model (LBM) allows simulate complex fluids, because its mesoscopic nature gives possibility to incorporate additional physics in comparison to usual methods. In this work, an improved lattice Boltzmann model for phase transition flow will be introduced. First, the state of art for Shan and Chen (SC) type of LBM will be reminded. Then, link to real thermodynamics will be established with Maxwell equal areas construction. Convergence to isothermal liquid vapor equilibrium will be shown and discussed. Inclusion of an equation of state for real fluid and better incorporation of force term is presented. Multi-range interactions have been used for SC model, but it hasn't been yet applied to real fluid with non-ideal equation of state. In this work, we evaluate this model when it is applied to real liquid-vapor equilibrium. We show that important differences are found for evaluation of gas density. In order to recover thermodynamic consistency, we use a new scheme for calculation of force term, which is a combination of multi range model and numerical weighting used by Gong and Cheng. We show the superiority of our new model by studying convergence to equilibrium values over a large temperature range. We prove that spurious velocities remaining at equilibrium are decreased.

Betel nut chewing associated with increased risk of arterial stiffness.

Science.gov (United States)

Wei, Yu-Ting; Chou, Yu-Tsung; Yang, Yi-Ching; Chou, Chieh-Ying; Lu, Feng-Hwa; Chang, Chih-Jen; Wu, Jin-Shang

2017-11-01

Betel nut chewing is associated with certain cardiovascular outcomes. Subclinical atherosclerosis may be one link between betel nut chewing and cardiovascular risk. Few studies have examined the association between chewing betel nut and arterial stiffness. The aim of this study was thus to determine the relationship between betel nut chewing and arterial stiffness in a Taiwanese population. We enrolled 7540 eligible subjects in National Cheng Kung University Hospital from October 2006 to August 2009. The exclusion criteria included history of cerebrovascular events, coronary artery disease, and taking lipid-lowering drugs, antihypertensives, and hypoglycemic agents. Increased arterial stiffness was defined as brachial-ankle pulse wave velocity (baPWV) ≥1400cm/s. According to their habit of betel nut use, the subjects were categorized into non-, ex-, and current chewers. The prevalence of increased arterial stiffness was 32.7, 43.3, and 43.2% in non-, ex- and current chewers, respectively (p=0.011). Multiple logistic regression analysis revealed that ex-chewers (odds ratio [OR] 1.69, 95% confidence interval (CI)=1.08-2.65) and current chewers (OR 2.29, 95% CI=1.05-4.99) had elevated risks of increased arterial stiffness after adjustment for co-variables. Both ex- and current betel nut chewing were associated with a higher risk of increased arterial stiffness. Stopping betel nut chewing may thus potentially be beneficial to reduce cardiovascular risk, based on the principals of preventive medicine. Copyright © 2017 Elsevier B.V. All rights reserved.

Development of subchannel analysis code MATRA-LMR for KALIMER subassembly thermal-hydraulics

International Nuclear Information System (INIS)

Won-Seok Kim; Young-Gyun Kim

2000-01-01

In the sodium cooled liquid metal reactors, the design limit are imposed on the maximum temperatures of claddings and fuel pins. Thus an accurate prediction of core coolant/fuel temperature distribution is essential to the LMR core thermal-hydraulic design. The detailed subchannel thermal-hydraulic analysis code MATRA-LMR (Multichannel Analyzer for Steady States and Transients in Rod Arrays for Liquid Metal Reactors) is being developed for KALIMER core design and analysis, based on COBRA-IV-i and MATRA. The major modifications and improvements implemented into MATRA-LMR are as follows: a) nonuniform axial noding capability, b) sodium properties calculation subprogram, c) sodium coolant heat transfer correlations, and d) most recent pressure drop correlations, such as Novendstern, Chiu-Rohsenow-Todreas and Cheng-Todreas. To assess the development status of this code, the benchmark calculations were performed with the ORNL 19 pin tests and EBR-II seven-assembly SLTHEN calculation results. The calculation results of MATRA-LMR for ORNL 19-pin assembly tests and EBR-II 91-pin experiments were compared to the measurements, and to SABRE4 and SLTHEN code calculation results, respectively. In this comparison, the differences are found among the three codes because of the pressure drop and the thermal mixing modellings. Finally, the major technical results of the conceptual design for the KALIMER 98.03 core have been compared with the calculations of MATRA-LMR, SABRE4 and SLTHEN codes. (author)

Peroxidase-like activity of nanocrystalline cobalt selenide and its application for uric acid detection

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Zhuang QQ

2017-04-01

Full Text Available Quan-Quan Zhuang,1 Zhi-Hang Lin,1 Yan-Cheng Jiang,1 Hao-Hua Deng,2 Shao-Bin He,1,3 Li-Ting Su,4 Xiao-Qiong Shi,2 Wei Chen2 1Department of Pharmacy, Affiliated Quanzhou First Hospital of Fujian Medical University, Quanzhou, 2Department of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University, Fuzhou, 3Department of Pharmacy, Quanzhou Infectious Disease Hospital, 4Department of Pharmaceutical Analysis, Quanzhou Medical College, Quanzhou, People’s Republic of China Abstract: Dendrite-like cobalt selenide nanostructures were synthesized from cobalt and selenium powder precursors by a solvothermal method in anhydrous ethylenediamine. The as-prepared nanocrystalline cobalt selenide was found to possess peroxidase-like activity that could catalyze the reaction of peroxidase substrates in the presence of H2O2. A spectrophotometric method for uric acid (UA determination was developed based on the nanocrystalline cobalt selenide-catalyzed coupling reaction between N-ethyl-N-(3-sulfopropyl-3-methylaniline sodium salt and 4-aminoantipyrine (4-AAP in the presence of H2O2. Under optimum conditions, the absorbance was proportional to the concentration of UA over the range of 2.0–40 µM with a detection limit of 0.5 µM. The applicability of the proposed method has been validated by determination of UA in human serum samples with satisfactory results. Keywords: enzyme mimics, cobalt selenide, peroxidase-like activity, uric acid, human serum

On Nonlinear Combustion Instability in Liquid Propellant Rocket Motors

Science.gov (United States)

Sims, J. D. (Technical Monitor); Flandro, Gary A.; Majdalani, Joseph; Sims, Joseph D.

2004-01-01

All liquid propellant rocket instability calculations in current use have limited value in the predictive sense and serve mainly as a correlating framework for the available data sets. The well-known n-t model first introduced by Crocco and Cheng in 1956 is still used as the primary analytical tool of this type. A multitude of attempts to establish practical analytical methods have achieved only limited success. These methods usually produce only stability boundary maps that are of little use in making critical design decisions in new motor development programs. Recent progress in understanding the mechanisms of combustion instability in solid propellant rockets"' provides a firm foundation for a new approach to prediction, diagnosis, and correction of the closely related problems in liquid motor instability. For predictive tools to be useful in the motor design process, they must have the capability to accurately determine: 1) time evolution of the pressure oscillations and limit amplitude, 2) critical triggering pulse amplitude, and 3) unsteady heat transfer rates at injector surfaces and chamber walls. The method described in this paper relates these critical motor characteristics directly to system design parameters. Inclusion of mechanisms such as wave steepening, vorticity production and transport, and unsteady detonation wave phenomena greatly enhance the representation of key features of motor chamber oscillatory behavior. The basic theoretical model is described and preliminary computations are compared to experimental data. A plan to develop the new predictive method into a comprehensive analysis tool is also described.

Sensitive detection and separation of fluorescent derivatives using capillary electrophoresis with laser-induced fluorescence detection with 532nm Nd:YAG laser

International Nuclear Information System (INIS)

Vrabel, Patrik; Taborsky, Petr; Ryvolova, Marketa; Havel, Josef; Preisler, Jan

2006-01-01

Capillary electrophoresis with laser-induced fluorescence detection (CELIF) is a powerful tool for separation and sensitive determination of fluorescent species. Biologically active compounds, such as amino acids, peptides and proteins may exhibit native fluorescence, which is however often low and/or an expensive laser is required for excitation in UV. Therefore, labelling of the analytes with a fluorescent dye is usually necessary. In this work, a home-built CELIF instrument with diode pumped frequency-doubled continuous wave Nd:YAG excitation laser with feedback power regulation (532nm) was constructed. The suitability of this type of laser for LIF detection in a separation method was found excellent. A limit of detection (LOD) (S/N=3) of 2x10 -13 mol/l was achieved with rhodamine B, which is comparable to those obtained using similar instruments with Ar + laser [Y.F. Cheng, N.J. Dovichi, Science 242 (1988) 562, E.S. Yeung et al., J. Chromatogr. 608 (1992) 73]. LOD of a protein derivatized according to modified procedures [M.J. Little et al., Anal. Chim. Acta 339 (1997) 279, A. Chersi et al., Biochim. Biophys. Acta 1336 (1997) 83] was determined. Detection of the derivatives was found to be limited by insufficient reaction recovery at low analyte concentration, chemical noise, separation efficiency and quality of the derivatizing reagent rather than by the detector performance. As a consequence, a huge gap between the detection ability of CELIF instruments and LOD determined in real samples is revealed

Particle acceleration at the magnetic poles of a neutron star

International Nuclear Information System (INIS)

Jones, P.B.

1977-01-01

The magnetic conversion of a photon in a neutron star magnetosphere near one of the magnetic poles is followed by acceleration of the electron and positron to ultra-relativistic energies. The positron moves along open magnetic flux lines to the light cylinder. The electron incident on the stellar surface produces an electromagnetic shower. Following a comment by Cheng and Ruderman (Astrophys.J.;214:598 (1977)), an order of magnitude estimate has been made of the spectrum of backward moving photons created in the electron shower. The most important source of photons is shown to be the formation of the giant dipole state in Fe 56 . Under the assumption that the surface magnetic flux density exceeds 10 12 G, the photons have, with high probability, mean free paths for magnetic conversion in the magnetosphere of 1 4 cm. An equation for the maximum acceleratin potential has been obtained in a one-dimensional model of pair creation and electron multiplication based on this photon source. The model has been applied to the phenomenon of subpulse drift in pulsars. The plasma accelerated at the magnetic pole has three components; positrons, protons and light nuclei (Z < approximately 6) formed by spallation, and iron group nuclei. Equations determining their relative fluxes have been found. The light nuclei include those with Z = 3 to 5, usually considered to be present in galactic cosmic rays only as a result of the interaction of heavier nuclei with the interstellar medium. (author)

Response to Commentary on Cheng, Broome, Feng, and Hu (2017) Leadership behaviours play a significant role in implementing evidence-based practice. Journal of Clinical Nursing, 2018;27:e1684-e1685.

Science.gov (United States)

Cheng, Lei; Feng, Sheng; Hu, Yan; Broome, Marion E

2018-06-12

Thank you for the opportunity to respond to Hu and Gifford's comments(Hu & Gifford, 2018). We appreciated their acknowledgement of our findings about the factors influencing the successful implementation of evidence-based practice (EBP). The authors described leadership behaviors as having a significant role in implementing evidence-based practice. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

Kinetic Alfven Waves at the Magnetopause-Mode Conversion, Transport and Formation of LLBL; TOPICAL

International Nuclear Information System (INIS)

Jay R. Johnson; C.Z. Cheng

2002-01-01

At the magnetopause, large amplitude, low-frequency (ULF), transverse MHD waves are nearly always observed. These waves likely result from mode conversion of compressional MHD waves observed in the magnetosheath to kinetic Alfven waves at the magnetopause where there is a steep gradient in the Alfven velocity[Johnson and Cheng, Geophys. Res. Lett. 24 (1997) 1423]. The mode-conversion process can explain the following wave observations typically found during satellite crossings of the magnetopause: (1) a dramatic change in wave polarization from compressional in the magnetosheath to transverse at the magnetopause, (2) an amplification of wave amplitude at the magnetopause, (3) a change in Poynting flux from cross-field in the magnetosheath to field-aligned at the magnetopause, and (4) a steepening in the wave power spectrum at the magnetopause. We examine magnetic field data from a set of ISEE1, ISEE2, and WIND magnetopause crossings and compare with the predictions of theoretical wave solutions based on the kinetic-fluid model with particular attention to the role of magnetic field rotation across the magnetopause. The results of the study suggest a good qualitative agreement between the observations and the theory of mode conversion to kinetic Alfven waves. Because mode-converted kinetic Alfven waves readily decouple particles from the magnetic field lines, efficient quasilinear transport (D(approx) 109m2/s) can occur. Moreover, if the wave amplitude is sufficiently large (Bwave/B0 and gt; 0.2) stochastic particle transport also occurs. This wave-induced transport can lead to significant heating and particle entry into the low latitude boundary layer across closed field lines.At the magnetopause, large amplitude, low-frequency (ULF), transverse MHD waves are nearly always observed. These waves likely result from mode conversion of compressional MHD waves observed in the magnetosheath to kinetic Alfven waves at the magnetopause where there is a steep gradient in

PREFACE: Inverse Problems in Applied Sciences—towards breakthrough

Science.gov (United States)

Cheng, Jin; Iso, Yuusuke; Nakamura, Gen; Yamamoto, Masahiro

2007-06-01

flourishing time, it is necessary to carefully analyse the current status of inverse problems for further development. Thus we have opened with the panel discussion entitled `Future of Inverse Problems' with panelists: Professors J Cheng, H W Engl, V Isakov, R Kress, J-K Seo, G Uhlmann and the commentator: Elaine Longden-Chapman from IOP Publishing. The aims of the panel discussion were to examine the current research status from various viewpoints, to discuss how we can overcome any difficulties and how we can promote young researchers and open new possibilities for inverse problems such as industrial linkages. As one output, the panel discussion has triggered the organization of the Inverse Problems International Association (IPIA) which has led to its first international congress in the summer of 2007. Another remarkable outcome of the conference is, of course, the present volume: this is the very high quality online proceedings volume of Journal of Physics: Conference Series. Readers can see in these proceedings very well written tutorial lecture notes, and very high quality original research and review papers all of which show what was achieved by the time the conference was held. The electronic publication of the proceedings is a new way of publicizing the achievement of the conference. It has the advantage of wide circulation and cost reduction. We believe this is a most efficient method for our needs and purposes. We would like to take this opportunity to acknowledge all the people who helped to organize the conference. Guest Editors Jin Cheng, Fudan University, Shanghai, China Yuusuke Iso, Kyoto University, Kyoto, Japan Gen Nakamura, Hokkaido University, Sapporo, Japan Masahiro Yamamoto, University of Tokyo, Tokyo, Japan

COPD in Taiwan: a National Epidemiology Survey

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Cheng SL

2015-11-01

Full Text Available Shih-Lung Cheng,1,2 Ming-Cheng Chan,3 Chin-Chou Wang,4 Ching-Hsiung Lin,5 Hao-Chien Wang,6 Jeng-Yuan Hsu,3 Liang-Wen Hang,7,8 Chee-Jen Chang,9 Diahn-Warng Perng,10,* Chong-Jen Yu6,* On behalf of the Taiwan COPD Consortium 1Department of Internal Medicine, Far Eastern Memorial Hospital, New Taipei City, 2Department of Chemical Engineering and Materials Science, Yuan Ze University, Chung-Li City, Taoyuan County, 3Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, 4Division of Pulmonary and Critical Care Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, 5Division of Chest Medicine, Changhua Christian Hospital, Changhua City, Changhua County, 6Department of Internal Medicine, National Taiwan University Hospital, Taipei, 7Department of Pulmonary and Critical Care Medicine, Sleep Medicine Center, China Medical University Hospital, 8Department of Respiratory Therapy, College of Health Care, China Medical University, Taichung, 9Biostatistical Center for Clinical Research, Chang Gung Memorial Hospital, Linkou Branch, Guishan Township, Taoyuan County, 10Department of Chest Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, Republic of China *These authors contributed equally to this work Objectives: To determine the prevalence of COPD in Taiwan and to document the disease characteristics and associated risk factors.Methods: We conducted a random cross-sectional national survey of adults older than 40 years in Taiwan. Respiratory health screening questions identified subjects with diagnosed COPD or whose reported symptoms also fulfilled an epidemiological case definition; these were eligible to complete the survey, which also included indices of symptom severity and disability and questions on comorbidities, medical treatments, smoking habits, and occupations potentially harmful to respiratory health. Subjects with diagnosed COPD were subdivided by smoking status. Subjects who fulfilled the case definition

Book Reviews

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Redactie KITLV

1974-04-01

Full Text Available - Umar Junus, Claire Holt, Culture and politics in Indonesia, Cornell Univ. Press, Ithaca and London, 1972. xi, 348 pp., maps, indexes., Benedict R. O’G. Anderson, James Siegel (eds. - S. Avé, Robert Stiller, Antologia Literatury Malajskiej. Biblioteka Narodowa, Zaklad Narodowy im. Ossolinskich, Wroclaw etc. 1971. 528 p. - H.J. Heering, J. van Baal, De boodschap der drie illusies. Van Gorcum & Co. Assen 1972. 135 blz. - The Siauw Giap, Goh Cheng Teik, The Malay Thirteenth incident and democracy in Malaysia. Oxford in Asia Current Affairs. Oxford University Press, Kula Lumpur & Singapore, 1971. 76 p. - W.F. Wertheim, Harry J. Benda, Continuity and change in Southeast Asia: Collected journal articles, Southeast Asia studies, Yale University, New Haven 1972, 307 p. - J.J. Ras, James Danandjaja, An annotated bibliography of Javanese folklore, Occasional paper no.9, Center for South and Southeast Asia studies, University of California, Berkeley, 1972, 162 pp. - I. Schöffer, Rob Nieuwenhuys, Oost Indische spiegel. Wat Nederlandse schrijvers en dichters over Indonesië hebben geschreven, vanaf de eerste jaren der Compagnie tot heden. Em. Querido, Amsterdam 1972. 645 blz. (Inleiding 11-18, Aantekeningen 555-621, Verantwoording 622-25, Namen en adressen 626, Woordenlijst 627-30, Register 631-45. - E. Postel-Coster, James L. Peacock, Indonesia; an anthropological perspective. Goodyear regional anthropological series, Edword Norbeck (ed.. Goodyear publishing company, Inc., Pacific Palisades, California, 1973. 168 pp. - C. Baks, O.H.K. Spate, India, Pakistan and Ceylon, the regions. Methuen and Co. Ltd., University Paperback 420, London 1972. 407-862 p., A.T.A. Learmouth, B.H. Farmer (eds. - ,

Computationally efficient models of neuromuscular recruitment and mechanics

Science.gov (United States)

Song, D.; Raphael, G.; Lan, N.; Loeb, G. E.

2008-06-01

We have improved the stability and computational efficiency of a physiologically realistic, virtual muscle (VM 3.*) model (Cheng et al 2000 J. Neurosci. Methods 101 117-30) by a simpler structure of lumped fiber types and a novel recruitment algorithm. In the new version (VM 4.0), the mathematical equations are reformulated into state-space representation and structured into a CMEX S-function in SIMULINK. A continuous recruitment scheme approximates the discrete recruitment of slow and fast motor units under physiological conditions. This makes it possible to predict force output during smooth recruitment and derecruitment without having to simulate explicitly a large number of independently recruited units. We removed the intermediate state variable, effective length (Leff), which had been introduced to model the delayed length dependency of the activation-frequency relationship, but which had little effect and could introduce instability under physiological conditions of use. Both of these changes greatly reduce the number of state variables with little loss of accuracy compared to the original VM. The performance of VM 4.0 was validated by comparison with VM 3.1.5 for both single-muscle force production and a multi-joint task. The improved VM 4.0 model is more suitable for the analysis of neural control of movements and for design of prosthetic systems to restore lost or impaired motor functions. VM 4.0 is available via the internet and includes options to use the original VM model, which remains useful for detailed simulations of single motor unit behavior.

Morphometric variations of three species of harvested cephalopods found in northern sea of Aceh Province, Indonesia

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ZAINAL ABIDIN MUCHLISIN

2014-10-01

Full Text Available Muchlisin ZA, Zulkarnaini B, Purnawan S, Muhadjier A, Fadli N, Cheng SH. 2014. Morphometric variations of three species of harvested cephalopods found in northern sea of Aceh Province, Indonesia. Biodiversitas 15: 142-146. The purpose of the present study was to evaluate the morphometrics of three harvested cephalopods, Sepioteuthis lessoniana, Sepia officinalis and Uroteuthis sp. found in northern sea of Aceh Province, Indonesia. Sampling was conducted for six months from July to December 2012 in one week interval. A total of 318 cephalopods; 139 Sepioteuthis lessoniana, 139 Uroteuthis sp. and 40 Sepia officinalis were analyzed for morphometric study and 13 anatomical characters were measured to the nearest 0.01 mm using a digital calipers. Morphometric measurements were significantly different between the different species of cephalopods (ANOVA, p<0.05. S. officinalis differed in six morphological characters (head length, head width, tentacles length, gladius width, rancis width and length from the squid species. Fin width and length were significantly greater in S. lessoniana than in S. officinalis and Uroteuthis sp. On the other hand, Uroteuthis sp. had significantly greater mantle lengths, standard lengths and gladius lengths than the other two cephalopod species (Duncan Test, p<0.05. However, fin width was similar between S. lessoniana and Uroteuthis sp., while eye diameter was similar between S. officinalis and Uroteuthis sp. A Discriminant Function Analysis scatter plot successfully discriminated the three species indicating significant differences in morphological variation. This analysis also indicates that morphometrically, S. lessoniana and S. officinalis are more similar to each other despite being in different orders.

Efecto manada en sectores económicos de las bolsas latinoamericanas: una visión pre y poscrisis subprime

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Juan Benjamín Duarte Duarte

2016-01-01

Full Text Available En los últimos a ̃ nos, el comportamiento de los agentes y lo que los motiva a tomar sus decisiones de inversión ha sido foco de estudio de muchos investigadores en las ramas de economía, finanzas y afines. Teniendo en cuenta esto, en este artículo se busca comprobar empíricamente uno de estos comportamientos, el efecto manada, mediante los modelos propuestos por Christie y Huang (1995 y Chang, Cheng y Khorana (2000, en el índice más representativo y en los sectores que lo componen, de los principales mercados de América Latina (Brasil, México, Chile, Colombia, Perú y Argentina para el periodo 2002-2014, así como en los subperiodos pre y poscrisis originados por las hipotecas subprime. Los hallazgos de esta investigación muestran que el efecto manada está presente en el índice más representativo del mercado bursátil de Colombia, Chile y Perú y en algunos de los sectores que lo componen, ya sea en el periodo total y/o en los subperiodos de pre y poscrisis; en el mercado de Brasil, el efecto está presente en el sector bancario en el periodo total y en el subperiodo de precrisis; en el mercado de Argentina tal efecto se presentó en el sector bancario y en el sector de petróleo y gas, y en el mercado de México no existe ninguna evidencia de dicho efecto

Rescuing cholinergic neurons from apoptotic degeneration by targeting of serotonin modulator- and apolipoprotein E-conjugated liposomes to the hippocampus

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Kuo YC

2016-12-01

Full Text Available Yung-Chih Kuo, Yin-Jung Lee Department of Chemical Engineering, National Chung Cheng University, Chia-Yi, Taiwan, Republic of China Abstract: β-Amyloid (Aβ-targeting liposomes (LIP with surface serotonin modulator (SM and apolipoprotein E (ApoE were utilized to facilitate the delivery of nerve growth factor (NGF across the blood–brain barrier (BBB for neuroprotection in the hippocampus. The therapeutic efficacy of SM- and ApoE-grafted LIP carrying NGF (NGF-SM-ApoE-LIP was assessed by an in vitro Alzheimer’s disease (AD model of degenerated SK-N-MC cells and an in vivo AD model of Aβ-insulted Wistar rats. The experimental evidences revealed that the modified SM and ApoE on the surface of LIP increased the permeation of NGF across the BBB without serious damage to structural integrity of tight junction. When compared with free NGF, NGF-SM-ApoE-LIP upregulated the expression of phosphorylated neurotrophic tyrosine kinase receptor type 1 on cholinergic neurons and significantly improved their survival. In addition, NGF-SM-ApoE-LIP could reduce the secretion of acetylcholinesterase and malondialdehyde and rescue hippocampal neurons from apoptosis in rat brains. The synergistic effect of SM and ApoE is promising in the induction of NGF to inhibit the neurotoxicity of Aβ and NGF-SM-ApoE-LIP can be a potent antiapoptotic pharmacotherapy for clinical care of patients with AD. Keywords: Alzheimer’s disease, blood–brain barrier, serotonin modulator, apolipoprotein E, nerve growth factor, liposome

Computer-aided classification of lung nodules on computed tomography images via deep learning technique

Directory of Open Access Journals (Sweden)

Hua KL

2015-08-01

Full Text Available Kai-Lung Hua,1 Che-Hao Hsu,1 Shintami Chusnul Hidayati,1 Wen-Huang Cheng,2 Yu-Jen Chen3 1Department of Computer Science and Information Engineering, National Taiwan University of Science and Technology, 2Research Center for Information Technology Innovation, Academia Sinica, 3Department of Radiation Oncology, MacKay Memorial Hospital, Taipei, Taiwan Abstract: Lung cancer has a poor prognosis when not diagnosed early and unresectable lesions are present. The management of small lung nodules noted on computed tomography scan is controversial due to uncertain tumor characteristics. A conventional computer-aided diagnosis (CAD scheme requires several image processing and pattern recognition steps to accomplish a quantitative tumor differentiation result. In such an ad hoc image analysis pipeline, every step depends heavily on the performance of the previous step. Accordingly, tuning of classification performance in a conventional CAD scheme is very complicated and arduous. Deep learning techniques, on the other hand, have the intrinsic advantage of an automatic exploitation feature and tuning of performance in a seamless fashion. In this study, we attempted to simplify the image analysis pipeline of conventional CAD with deep learning techniques. Specifically, we introduced models of a deep belief network and a convolutional neural network in the context of nodule classification in computed tomography images. Two baseline methods with feature computing steps were implemented for comparison. The experimental results suggest that deep learning methods could achieve better discriminative results and hold promise in the CAD application domain. Keywords: nodule classification, deep learning, deep belief network, convolutional neural network

An EST dataset for Metasequoia glyptostroboides buds: the first EST resource for molecular genomics studies in Metasequoia.

Science.gov (United States)

Zhao, Ying; Thammannagowda, Shivegowda; Staton, Margaret; Tang, Sha; Xia, Xinli; Yin, Weilun; Liang, Haiying

2013-03-01

The "living fossil" Metasequoia glyptostroboides Hu et Cheng, commonly known as dawn redwood or Chinese redwood, is the only living species in the genus and is valued for its essential oil and crude extracts that have great potential for anti-fungal activity. Despite its paleontological significance and economical value as a rare relict species, genomic resources of Metasequoia are very limited. In order to gain insight into the molecular mechanisms behind the formation of reproductive buds and the transition from vegetative phase to reproductive phase in Metasequoia, we performed sequencing of expressed sequence tags from Metasequoia vegetative buds and female buds. By using the 454 pyrosequencing technology, a total of 1,571,764 high-quality reads were generated, among which 733,128 were from vegetative buds and 775,636 were from female buds. These EST reads were clustered and assembled into 114,124 putative unique transcripts (PUTs) with an average length of 536 bp. The 97,565 PUTs that were at least 100 bp in length were functionally annotated by a similarity search against public databases and assigned with Gene Ontology (GO) terms. A total of 59 known floral gene families and 190 isotigs involved in hormone regulation were captured in the dataset. Furthermore, a set of PUTs differentially expressed in vegetative and reproductive buds, as well as SSR motifs and high confidence SNPs, were identified. This is the first large-scale expressed sequence tags ever generated in Metasequoia and the first evidence for floral genes in this critically endangered deciduous conifer species.