WorldWideScience

Sample records for early type non-liner

  1. Chandra Early Type Galaxy Atals

    Science.gov (United States)

    Kim, Dong-Woo; Anderson, Craig; Burke, Douglas J.; Fabbiano, Giuseppina; Fruscione, Antonella; Lauer, Jennifer; McCollough, Michael; Morgan, Douglas; Mossman, Amy; O'Sullivan, Ewan; Paggi, Alessandro; Vrtilek, Saeqa Dil; Trinchieri, Ginevra

    2017-08-01

    The hot gas in early type galaxies (ETGs) plays a crucial role in understanding their formation and evolution. As the hot gas is often extended to the outskirts beyond the optical size, the large scale structural features identified by Chandra (including jets, cavities, cold fronts, filaments and tails) point to key evolutionary mechanisms, e.g., AGN feedback, merging history, accretion, stripping and star formation and its quenching. We have systematically analyzed the archival Chandra data of ~100 ETGs to study the hot ISM. We produce the uniformly derived data products with spatially resolved spectral information and will make them accessible via a public web site. With 2D spectral infomation, we further discuss gas morphology, scaling relations, X-ray based mass profiles and their implications related to various physical mechanisms (e.g., stellar and AGN feedback).

  2. Virgo Early-Type Dwarfs in ALFALFA

    CERN Document Server

    Koopmann, Rebecca A

    2007-01-01

    Early-type dwarf galaxies dominate cluster populations, but their formation and evolutionary histories are poorly understood. The ALFALFA (Arecibo Legacy Fast ALFA) survey has completed observations of the Virgo Cluster in the declination range of 6 - 16 degrees. Less than 2% of the early-type dwarf population is detected, a significantly lower fraction than reported in previous papers based on more limited samples. In contrast ~30 of the irregular/BCD dwarf population is detected. The detected early-type galaxies tend to be located in the outer regions of the cluster, with a concentration in the direction of the M Cloud. Many show evidence for ongoing/recent star formation. Galaxies such as these may be undergoing morphological transition due to cluster environmental effects.

  3. Magnetic fields in early-type stars

    CERN Document Server

    Grunhut, Jason H

    2015-01-01

    For several decades we have been cognizant of the presence of magnetic fields in early-type stars, but our understanding of their magnetic properties has recently (over the last decade) expanded due to the new generation of high-resolution spectropolarimeters (ESPaDOnS at CFHT, Narval at TBL, HARPSpol at ESO). The most detailed surface magnetic field maps of intermediate-mass stars have been obtained through Doppler imaging techniques, allowing us to probe the small-scale structure of these stars. Thanks to the effort of large programmes (e.g. the MiMeS project), we have, for the first time, addressed key issues regarding our understanding of the magnetic properties of massive (M > 8 M_sun) stars, whose magnetic fields were only first detected about fifteen years ago. In this proceedings article we review the spectropolarimetric observations and statistics derived in recent years that have formed our general understanding of stellar magnetism in early-type stars. We also discuss how these observations have fu...

  4. Type II supernovae Early Light Curves

    CERN Document Server

    Shussman, Tomer; Nakar, Ehud

    2016-01-01

    Observations of type II supernova early light, from breakout until recombination, can be used to constrain the explosion energy and progenitor properties. Currently available for this purpose are purely analytic models, which are accurate only to within an order of magnitude, and detailed numerical simulations, which are more accurate but are applied to any event separately. In this paper we derive an analytic model that is calibrated by numerical simulations. This model is much more accurate than previous analytic models, yet it is as simple to use. To derive the model we analyze simulated light curves from numerical explosion of $124$ red supergiant progenitors, calculated using the stellar evolution code MESA. We find that although the structure of the progenitors we consider varies, the resulting light curves can be described rather well based only on the explosion energy, ejecta mass and progenitor radius. Our calibrated analytic model, which is based on these three parameters, reproduces the bolometric ...

  5. Hidden AGNs in Early-Type Galaxies

    CERN Document Server

    Paggi, A; Civano, F; Pellegrini, S; Elvis, M; Kim, D -W

    2015-01-01

    We present a stacking analysis of the complete sample of Early Type Galaxies (ETGs) in the \\textit{Chandra} COSMOS (C-COSMOS) survey, to explore the nature of the X-ray luminosityin the redshift and stellar luminosity ranges \\(0

  6. Early emission from type Ia supernovae

    CERN Document Server

    Rabinak, Itay; Waxman, Eli

    2011-01-01

    A unique feature of deflagration-to-detonation (DDT) white dwarf explosion models of SNe of type Ia is the presence of a strong shock wave propagating through the outer envelope. We consider the early emission expected in such models, which is produced by the expanding shock-heated outer part of the ejecta and precedes the emission driven by radioactive decay. We expand on earlier analyses by considering the modification of the pre-detonation density profile by the weak-shocks generated during the deflagration phase, the time evolution of the opacity, and the deviation of the post-shock equation of state from that obtained for radiation pressure domination. A simple analytic model is presented and shown to provide an acceptable approximation to the results of 1D numerical DDT simulations. Our analysis predicts a thousand second long UV/optical flash with a luminosity of ~1 to 3*1e39 erg/s. Lower luminosity corresponds to faster (turbulent) deflagration velocity. The predicted luminosity of the UV flash is an ...

  7. Characterization of Kepler early-type targets

    CERN Document Server

    Catanzaro, G; Molenda-Zakowicz, J; Marilli, E; 10.1051/0004-6361/201014189

    2010-01-01

    Stellar pulsation offers a unique opportunity to constrain the intrinsic parameters of stars and unveil their inner structure. The Kepler satellite is collecting an enormous amount of data of unprecedent photometric precision, which will allow us to test theory and obtain a very precise tomography of stellar interiors. We attempt to determine the stars' fundamental parameters Teff, log g, v sin i, and luminosity needed for computing asteroseismic models and interpreting Kepler data. We report spectroscopic observations of 23 early-type Kepler asteroseismic targets, 13 other stars in the Kepler field, that had not been selected to be observed. We measured the radial velocity by performing a cross-correlation with template spectra to help us identify non-single stars. Spectral synthesis was performed to derive the stellar parameters of our target stars, and the state-of-the-art LTE atmospheric models were computed. For all the stars of our sample, we derived the radial velocity, Teff, log g, v sin i, and lumino...

  8. EARLY EMISSION FROM TYPE Ia SUPERNOVAE

    Energy Technology Data Exchange (ETDEWEB)

    Rabinak, Itay; Waxman, Eli [Department of Particle Physics and Astrophysics, Weizmann Institute of Science, Rehovot 76100 (Israel); Livne, Eli, E-mail: itay.rabinak@weizmann.ac.il [Racah Institute of Physics, Hebrew University, Jerusalem (Israel)

    2012-09-20

    A unique feature of deflagration-to-detonation (DDT) white dwarf explosion models of supernovae of type Ia is the presence of a strong shock wave propagating through the outer envelope. We consider the early emission expected in such models, which is produced by the expanding shock-heated outer part of the ejecta and precedes the emission driven by radioactive decay. We expand on earlier analyses by considering the modification of the pre-detonation density profile by the weak shocks generated during the deflagration phase, the time evolution of the opacity, and the deviation of the post-shock equation of state from that obtained for radiation pressure domination. A simple analytic model is presented and shown to provide an acceptable approximation to the results of one-dimensional numerical DDT simulations. Our analysis predicts a {approx}10{sup 3} s long UV/optical flash with a luminosity of {approx}1 to {approx}3 Multiplication-Sign 10{sup 39} erg s{sup -1}. Lower luminosity corresponds to faster (turbulent) deflagration velocity. The luminosity of the UV flash is predicted to be strongly suppressed at t > t{sub drop} {approx} 1 hr due to the deviation from pure radiation domination.

  9. Directly detecting the evolution of early-type galaxies

    NARCIS (Netherlands)

    Trager, Scott; Faber, SM; Dressler, A; Renzini, A; Bender, R

    2005-01-01

    We describe observations focused on understanding the epochs and timescales of the formation and evolution of early-type galaxies, particularly those in clusters. We show that while early-type cluster galaxies are on average older and closer to coeval than their counterparts in the field, significan

  10. Early Menopause May Be Tied to Type 2 Diabetes

    Science.gov (United States)

    ... https://medlineplus.gov/news/fullstory_167305.html Early Menopause May Be Tied to Type 2 Diabetes When ... risk is 4 times greater compared to late menopause, study suggests To use the sharing features on ...

  11. Selective Attention in Early Dementia of Alzheimer Type

    Science.gov (United States)

    Fernandez-Duque, Diego; Black, Sandra E.

    2008-01-01

    This study explored possible deficits in selective attention brought about by Dementia of Alzheimer Type (DAT). In three experiments, we tested patients with early DAT, healthy elderly, and young adults under low memory demands to assess perceptual filtering, conflict resolution, and set switching abilities. We found no evidence of impaired…

  12. The Initial Mass Function of Early-Type Galaxies

    NARCIS (Netherlands)

    Treu, Tommaso; Auger, Matthew W.; Koopmans, Léon V. E.; Gavazzi, Raphaël; Marshall, Philip J.; Bolton, Adam S.

    2010-01-01

    We determine an absolute calibration of the initial mass function (IMF) of early-type galaxies, by studying a sample of 56 gravitational lenses identified by the Sloan Lenses ACS Survey. Under the assumption of standard Navarro, Frenk, and White dark matter halos, a combination of lensing, dynamical

  13. Do AGN suppress star formation in early-type galaxies?

    OpenAIRE

    Schawinski, Kevin

    2010-01-01

    The observation that AGN host galaxies preferentially inhabit the "green valley" between the blue cloud and the red sequence has significant consequences for our understanding of the co-evolution of galaxies and black holes via accretion events. I discuss the interpretation of green valley AGN host galaxy colours with particular focus on early-type galaxies.

  14. Observational evidence for AGN feedback in early-type galaxies

    CERN Document Server

    Schawinski, Kevin; Sarzi, Marc; Maraston, Claudia; Kaviraj, Sugata; Joo, Seok-Joo; Yi, Sukyoung K; Silk, Joseph

    2007-01-01

    A major amendment in recent models of hierarchical galaxy formation is the inclusion of so-called AGN feedback. The energy input from an active central massive black hole is invoked to suppress star formation in early-type galaxies at later epochs. A major problem is that this process is poorly understood, and compelling observational evidence for its mere existence is still missing. In search for signatures of AGN feedback, we have compiled a sample of 16,000 early-type galaxies in the redshift range 0.05early-types inhabit the blue cloud, while early-types with AGN are located considerably closer to and almost on the red sequence. S...

  15. Early risk stratification in pediatric type 1 diabetes

    DEFF Research Database (Denmark)

    Broe, Rebecca

    2015-01-01

    In the late 1980s all Danish children with type 1 diabetes were invited for a nationwide evaluation of glycemic control. Approximately 75% (n = 720) participated and have later been referred to as The Danish Cohort of Pediatric Diabetes 1987 (DCPD1987). The results were surprisingly poor glycemic...... with PDR over the study period, which in accordance with DCCT should have prevented the development of PDR to some extent. A surprisingly high incidence of proliferative retinopathy amongst young patients with type 1 diabetes in Denmark was found despite improvements in HbA1c over time. The improvement...... in HbA1c was either too small or happened too late. This study highlights that sight-threatening diabetic retinopathy remain a major concern in type 1 diabetes and the importance of early glycemic control. Identifying high-risk patients at a very early stage is not only desired for prevention...

  16. Strontium and Barium In Early-Type Galaxies

    CERN Document Server

    Conroy, Charlie; Graves, Genevieve J

    2013-01-01

    The detailed abundance patterns of the stars within galaxies provide a unique window into the history of star formation (SF) at early times. Two widely used `chronometers' include the alpha and iron-peak elements, which are created on short and long timescales, respectively. These two clocks have been widely used to estimate SF timescales from moderate-resolution spectra of early-type galaxies. Elements formed via s-process neutron captures (e.g., Sr and Ba) comprise a third type of chronometer, as the site of the main s-process is believed to be intermediate and low-mass asymptotic giant branch stars. The [alpha/Ba] ratio in particular should provide a powerful new constraint on the SF histories of galaxies, in part because it is insensitive to the uncertain distribution of type Ia SNe detonation times and the overall Ia rate. Here we present new measurements of the abundance of Sr and Ba in nearby early-type galaxies by applying stellar population synthesis tools to high S/N optical spectra. We find a stron...

  17. The Origin of Dwarf Early-Type Galaxies

    CERN Document Server

    Toloba, Elisa

    2012-01-01

    Abridge. We have conducted a spectrophotometric study of dwarf early-type galaxies (dEs) in the Virgo cluster and in regions of lower density. We have found that these galaxies show many properties in common with late-type galaxies but not with more massive early-types (E/S0). The properties of the dEs in Virgo show gradients within the cluster. dEs in the outer parts of the Virgo cluster are kinematically supported by rotation, while those in the center are supported by the random motions of their stars (i.e. pressure supported). The rotationally supported dEs have disky isophotes and faint underlying spiral/irregular substructures, they also show younger ages than those pressure supported, which have boxy isophotes and are smooth and regular, without any substructure. We compare the position of these dEs with massive early-type galaxies in the Faber-Jackson and Fundamental Plane relations, and we find that, although there is no difference between the position of rotationally and pressure supported dEs, both...

  18. Structures in the fundamental plane of early-type galaxies

    CERN Document Server

    Fraix-Burnet, Didier; Chattopadhyay, Tanuka; Chattopadhyay, Asis Kumar; Davoust, Emmanuel

    2010-01-01

    The fundamental plane of early-type galaxies is a rather tight three-parameter correlation discovered more than twenty years ago. It has resisted a both global and precise physical interpretation despite a consequent number of works, observational, theoretical or using numerical simulations. It appears that its precise properties depend on the population of galaxies in study. Instead of selecting a priori these populations, we propose to objectively construct homologous populations from multivariate analyses. We have undertaken multivariate cluster and cladistic analyses of a sample of 56 low-redshift galaxy clusters containing 699 early-type galaxies, using four parameters: effective radius, velocity dispersion, surface brightness averaged over effective radius, and Mg2 index. All our analyses are consistent with seven groups that define separate regions on the global fundamental plane, not across its thickness. In fact, each group shows its own fundamental plane, which is more loosely defined for less diver...

  19. GALEX UV Color Relations for Nearby Early-Type Galaxies

    CERN Document Server

    Donas, J; Rich, R M; Yi, S K; Lee, Y W; Boselli, A; De Paz, A G; Boissier, S; Charlot, S; Salim, S; Bianchi, L; Barlow, T A; Forster, K; Friedman, P G; Heckman, T M; Madore, B F; Martin, D C; Milliard, B; Morrissey, P; Neff, S G; Schiminovich, D; Seibert, M; Small, T; Szalay, A S; Welsh, B Y; Wyder, T K; Donas, Jose; Deharveng, Jean-Michel; Yi, Sukyoung K.; Lee, Young-Wook; Boselli, Alessandro; Paz, Armando Gil de; Boissier, Samuel; Charlot, Stephane; Salim, Samir; Bianchi, Luciana; Barlow, Tom A.; Forster, Karl; Friedman, Peter G.; Heckman, Timothy M.; Madore, Barry F.; Milliard, Bruno; Morrissey, Patrick; Neff, Susan G.; Schiminovich, David; Seibert, Mark; Small, Todd; Szalay, Alex S.; Welsh, Barry Y.; Wyder, Ted K.

    2006-01-01

    We use GALEX/optical photometry to construct color-color relationships for early-type galaxies sorted by morphological type. We have matched objects in the GALEX GR1 public release and the first IR1.1 internal release, with the RC3 early-type galaxies having a morphological type -5.5

  20. Early feeding and risk of type 1 diabetes

    DEFF Research Database (Denmark)

    Knip, Mikael; Virtanen, Suvi M; Becker, Dorothy

    2011-01-01

    Short-term breastfeeding and early exposure to complex dietary proteins, such as cow milk proteins and cereals, or to fruit, berries, and roots have been implicated as risk factors for ß cell autoimmunity, clinical type 1 diabetes, or both. The Trial to Reduce Insulin-dependent diabetes mellitus...... in the Genetically at Risk (TRIGR) is an international, randomized, double-blind, controlled intervention trial designed to answer the question of whether weaning to an extensively hydrolyzed formula in infancy will decrease the risk of type 1 diabetes later in childhood. In our pilot study, weaning to a highly...... recruited 5606 newborn infants with a family member affected by type 1 diabetes and enrolled 2159 eligible subjects who carried a risk-conferring HLA genotype. All recruited mothers were encouraged to breastfeed. The intervention lasted for 6-8 mo with a minimum study formula exposure time of 2 mo...

  1. STRONTIUM AND BARIUM IN EARLY-TYPE GALAXIES

    Energy Technology Data Exchange (ETDEWEB)

    Conroy, Charlie [Department of Astronomy and Astrophysics, University of California, Santa Cruz, CA (United States); Van Dokkum, Pieter G. [Department of Astrophysical Sciences, Yale University, New Haven, CT (United States); Graves, Genevieve J. [Department of Astronomy, University of California, Berkeley, CA (United States)

    2013-02-01

    The detailed abundance patterns of the stars within galaxies provide a unique window into the history of star formation (SF) at early times. Two widely used 'chronometers' include the {alpha} and iron-peak elements, which are created on short and long timescales, respectively. These two clocks have been widely used to estimate SF timescales from moderate-resolution spectra of early-type galaxies. Elements formed via s-process neutron captures (e.g., Sr and Ba) comprise a third type of chronometer, as the site of the main s-process is believed to be intermediate and low-mass asymptotic giant branch stars. The [{alpha}/Ba] ratio in particular should provide a powerful new constraint on the SF histories of galaxies, in part because it is insensitive to the uncertain distribution of Type Ia supernovae detonation times and the overall Ia rate. Here we present new measurements of the abundance of Sr and Ba in nearby early-type galaxies by applying stellar population synthesis tools to high signal-to-noise optical spectra. We find a strong anti-correlation between [Mg/Fe] and [Ba/Fe], and a strong positive correlation between [Mg/Ba] and galaxy velocity dispersion. These trends are consistent with the idea that more massive galaxies formed their stars on shorter timescales compared to less massive galaxies, and rule out several other proposed explanations for the observed super-solar [Mg/Fe] values in massive galaxies. In contrast, [Sr/Fe] {approx}0, with no strong variation across the sample. It is difficult to interpret the Sr trends without detailed chemical evolution models owing to the multiplicity of proposed nucleosynthetic sites for Sr.

  2. Extended, regular HI structures around early-type galaxies

    CERN Document Server

    Oosterloo, T; Sadler, E M; Van der Hulst, J M; Serra, P

    2007-01-01

    We discuss the morphology and kinematics of the HI of a sample of 30 southern gas-rich early-type galaxies selected from the HI Parkes All-Sky Survey (HIPASS). This is the largest collection of high-resolution HI data of a homogeneously selected sample. Given the sensitivity of HIPASS, these galaxies represent the most HI-rich early-type galaxies. In two-thirds of the galaxies, we find the HI to be in a large, regular disk- or ring-like structure that in some cases is strongly warped. In the remaining cases we find the HI distributed in irregular tails or clouds offset from the galaxy. The giant, regular HI structures can be up to ~200 kpc in diameter and contain up to 10^10 M_sun of HI. The incidence of irregular HI structures appears to be somewhat higher in elliptical galaxies, but the large, regular structures are observed in both elliptical and S0 galaxies and are not strictly connected to the presence of a stellar disk. If these two types of galaxies are the result of different formation paths, this is ...

  3. Non-thermal emission from early-type stars

    CERN Document Server

    Benaglia, P

    2006-01-01

    Massive, early-type stars deposit energy and momentum in the interstellar medium through dense, supersonic winds. These objects are one of the most important sources of ionising radiation and chemical enrichment in the Galaxy. The physical conditions in the winds give rise to thermal and non-thermal emission, detectable from radio to gamma rays. In this report the relevant radiation processes will be described and studies on particular systems will be presented, discussing the information provided by multifrequency observations. Future steps aiming at understanding the stellar wind phenomenon as a whole will be outlined.

  4. Time for testing incretin therapies in early type 1 diabetes?

    Science.gov (United States)

    Bosi, Emanuele

    2010-06-01

    Incretin-based compounds, including glucagon-like peptide-1 receptor agonists and dipeptidyl-peptidase-4 inhibitors, have emerged as a new class of agents for the treatment of type 2 diabetes. In this article, the potential and supporting evidence for extending their use to early type 1 diabetes are reviewed. The rationale relies on the assumption that these drugs, in addition to their action on insulin secretion and glucose regulation, may be effective in preserving and even expanding the beta-cell mass. This assumption is based on data from in vitro and animal studies, with no clear demonstrations in humans. This class of drugs may represent an entirely new approach to the treatment of type 1 diabetes, focused on protection and preservation of beta-cells, an ideal complement to immune interventions inhibiting or modulating the pathogenetic autoimmune process. The ideal candidates for this treatment are patients at the time of clinical onset of type 1 diabetes or individuals with preclinical type 1 diabetes who still have a significant viable beta-cell mass.

  5. Early-type objects in NGC6611 and Eagle Nebula

    CERN Document Server

    Martayan, Christophe; Hubert, Anne-Marie; Neiner, Coralie; Fremat, Yves; Baade, Dietrich; Fabregat, Juan

    2008-01-01

    An important question about Be stars is whether Be stars are born as Be stars or not. It is necessary to observe young clusters to answer this question. Observations of stars in NGC6611 and the star-formation region of Eagle Nebula have been carried out with the ESO-WFI in slitless spectroscopic mode and at the VLT-GIRAFFE. The targets for the GIRAFFE observations were pre-selected from the literature and our catalogue of emission-line stars (ELS) based on the WFI study. GIRAFFE observations allowed us to study accurately the population of the early-type stars with and without emission lines. For this study, we determined the fundamental parameters of OBA stars. We also studied the status of the objects (main sequence or pre-main sequence stars) by using IR data, membership probabilities, and location in HR diagrams. The nature of the early-type ELS in M16 is derived. The slitless observations with the WFI clearly indicate a small number of ELS in M16. We observed with GIRAFFE 101 OBA stars, among them 9 are ...

  6. Peculiar early-type galaxies with central star formation

    Institute of Scientific and Technical Information of China (English)

    Chong Ge; Qiu-Sheng Gu

    2012-01-01

    Early-type galaxies (ETGs) are very important for understanding the formation and evolution of galaxies.Recent observations suggest that ETGs are not simply old stellar spheroids as we previously thought.Widespread recent star formation,cool gas and dust have been detected in a substantial fraction of ETGs.We make use of the radial profiles of g - r color and the concentration index from the Sloan Digital Sky Survey database to pick out 31 peculiar ETGs with central blue cores.By analyzing the photometric and spectroscopic data,we suggest that the blue cores are caused by star formation activities rather than the central weak active galactic nucleus.From the results of stellar population synthesis,we find that the stellar population of the blue cores is relatively young,spreading from several Myr to less than one Gyr.In 14 galaxies with H I observations,we find that the average gas fraction of these galaxies is about 0.55.The bluer galaxies show a higher gas fraction,and the total star formation rate (SFR) correlates very well with the H l gas mass.The star formation history of these ETGs is affected by the environment,e.g.in the denser environment the H 1 gas is less and the total SFR is lower.We also discuss the origin of the central star formation of these early-type galaxies.

  7. Observations of hydroxyl in early-type galaxies

    CERN Document Server

    McBride, James; Nyland, Kristina

    2014-01-01

    We used Arecibo Observatory and the Green Bank Telescope to observe OH in twelve early-type galaxies with known reservoirs of dense gas. We present three new detections of OH in absorption in the 1667 MHz line. One objective of our survey was to find evidence of molecular outflows, but our sensitivity, and the strength of the OH absorption, were insufficient to detect outflows. The detected sources have infrared luminosities and dust temperatures among the lowest of any galaxy detected in OH absorption. The ratio $L_{\\rm HCN} / L_{\\rm CO}$, a measure of the dense gas fraction in galaxies, is a powerful selector of OH megamasers for galaxies with high infrared luminosity. In early-type galaxies, which have much lower infrared luminosities, $L_{\\rm HCN} / L_{\\rm CO}$ is also a promising tool for discovering OH, but in absorption rather than in maser emission. In addition to dense molecular gas, a radio continuum source and a favorable line-of-sight to the observer are likely key factors in detecting OH absorber...

  8. HI Gas in Early Type Galaxies as Measured by ALFALFA

    Science.gov (United States)

    Collins, Wendy; Morrison, Ryan; Green, Jarred; Raskin, Mark; Crawford, Connor; Bomer-Lawson, August; Hannan, Joshua; Crone-Odekon, Mary; ALFALFA Team

    2016-01-01

    We present the HI content of 1580 early type galaxies (ETGs) in a total sample of 7747 galaxies that have HI measurements or upper limits from the ALFALFA survey. We find a significant correlation between HI content and local density, with HI detections almost exclusively in low-density environments. Using optical line ratios, we split the population into galaxies with spectral lines dominated by active galactic nuclei (AGN) and dominated by star forming regions. Compared with HI-rich star forming ETGs, HI-rich ETGs with AGN tend to be brighter and redder and to exhibit a stronger correlation between stellar mass and HI mass. This work is supported by NSF grant AST-1211005.

  9. Central dark matter trends in early-type galaxies .

    Science.gov (United States)

    Tortora, C.; Napolitano, N. R.; Romanowsky, A. J.; Jetzer, Ph.

    We analyze the correlations between the central dark matter content of early-type galaxies and their sizes and ages, using a sample of intermediate-redshift (z˜ 0.2) gravitational lenses from the SLACS survey, and by comparing them to a larger sample of z˜0 galaxies. For a given stellar mass, we find that for galaxies with larger sizes, the DM fraction increases and the mean DM density decreases, consistently with the cuspy halos expected in cosmological formation scenarios. The DM fraction also decreases with stellar age, which can be partially explained by the inverse correlation between size and age. The residual trend may point to systematic dependencies on formation epoch of halo contraction or stellar initial mass functions.

  10. Kinematics of early-type galaxies from the Nuker sample

    Science.gov (United States)

    Pinkney, J.; Gebhardt, K.; Bender, R.; Richstone, D.; Nuker Team

    2000-05-01

    The Nuker team has STIS Ca triplet spectroscopy of the centers of 10 early-type galaxies. We have measured the first four moments of the losvd's from these data using three techniques: FQ, FCQ and Penalized Maximum Likelihood. To complement the modelling of the stellar orbital structure (Gebhardt, this session), we will compare these moments to other properties of the galaxies. These properties include the ground-based kinematics (e.g., global dispersion) and photometric properties (e.g., bulge luminosity). The sample shows a tendancy toward negative H4 values (i.e., boxy losvd's) near the center. The galaxies that are significantly negative are N3608 and N4473, both of which show signs of merger. We acknowledge support from HST grant GO-07388.01 and LTSA grant NAG5-8238 to D. Richstone.

  11. Probing early-type galaxy evolution with the Kormendy relation

    CERN Document Server

    Ziegler, B L; Bender, R; Belloni, P; Greggio, L; Seitz, S

    1999-01-01

    We investigate the evolution of early-type galaxies in four clusters at z=0.4 (Abell370, Cl0303+17, Cl0939+47 and Cl1447+26) and in one at z=0.55 (Cl0016+16). The galaxies are selected according to their spectrophotometrically determined spectral types and comprise the morphological classes E, S0 and Sa galaxies. Structural parameters are determined by a two-component fitting of the surface brightness profiles derived from HST images. Exploring a realistic range of K-corrections using Bruzual and Charlot models, we construct the rest-frame B-band Kormendy relations (mu_e-log(R_e)) for the different clusters. We do not detect a systematic change of the slope of the relation as a function of redshift. We discuss in detail how the luminosity evolution, derived by comparing the Kormendy relations of the distant clusters with the local one for Coma, depends on various assumptions and give a full description of random and systematic errors by exploring the influences of selection bias, different star formation hist...

  12. Extended nebular emission in CALIFA early-type galaxies

    CERN Document Server

    Gomes, J M; Kehrig, C; Vílchez, J M; Lehnert, M D

    2015-01-01

    The morphological, spectroscopic and kinematical properties of the warm interstellar medium (wim) in early-type galaxies (ETGs) hold key observational constraints to nuclear activity and the buildup history of these massive quiescent systems. High-quality integral field spectroscopy (IFS) data with a wide spectral and spatial coverage, such as those from the CALIFA survey, offer a precious opportunity for advancing our understanding in this respect. We use deep IFS data from CALIFA (califa.caha.es) to study the wim over the entire extent and optical spectral range of 32 nearby ETGs. We find that all ETGs in our sample show faint (H\\alpha\\ equivalent width EW~0.5...2 {\\AA}) extranuclear nebular emission extending out to >= 2 Petrosian_50 radii. Confirming and strengthening our conclusions in Papaderos et al. (2013) we argue that ETGs span a broad continuous sequence with regard to the properties of their wim, and they can be roughly subdivided into two characteristic classes. The first one (type i) comprises E...

  13. Parameters testing and non-liner hyper-elastic strain modeling for soft tissue%软组织非线性物理建模及其参数测定

    Institute of Scientific and Technical Information of China (English)

    王洪瑞; 董斌

    2012-01-01

    The human soft tissue modeling is still a bottleneck for realistic soft tissue simulation. A novel soft tissue modeling method is proposed to improve the reality in this paper. Firstly, the volume-spring mass model is employed, and the biomechanics method is used to build the force model of the soft tissue. Then the springs is modeled with the non-liner hyper-elastic strain energy function for bio-tissues, the parameters of the model is calculated with the values tested by the ex vivo experiment on pig liver tissue, and the soft tissue model based on the physical character is obtained. The utility of improving the reality of virtual surgery system is verified by the experiment.%对现有虚拟手术中人体软组织建模方法进行了分析,针对目前软组织建模真实性还有待提高的问题,提出了一种新的软组织建模方法.首先,在引入体弹簧质点模型的基础上,利用生物力学方法建立了适合软组织力学仿真的模型.然后通过非线性超弹性应变能方程对弹簧力建模,并根据真实肝脏软组织物理特性的测量结果求解模型参数,得到基于物理特性的软组织模型.通过实验验证,该方法在提升虚拟手术触觉沉浸感方面具有可行性和有效性.

  14. Implications for the origin of early-type dwarf galaxies - the discovery of rotation in isolated, low-mass early-type galaxies

    Science.gov (United States)

    Janz, Joachim; Penny, Samantha J.; Graham, Alister W.; Forbes, Duncan A.; Davies, Roger L.

    2017-07-01

    We present the discovery of rotation in quenched, low-mass early-type galaxies that are isolated. This finding challenges the claim that (all) rotating dwarf early-type galaxies in clusters were once spiral galaxies that have since been harassed and transformed into early-type galaxies. Our search of the Sloan Digital Sky Survey data within the Local Volume (z half-light radius Re in the best cases, and beyond Re/2 for all. They reveal a variety of behaviours similar to those of a comparison sample of early-type dwarf galaxies in the Virgo cluster observed by Toloba et al. Both samples have similar frequencies of slow and fast rotators, as well as kinematically decoupled cores. This, and especially the finding of rotating quenched low-mass galaxies in isolation, reveals that the early-type dwarfs in galaxy clusters need not be harassed or tidally stirred spiral galaxies.

  15. The redshift evolution of early-type galaxies in COSMOS: Do massive early-type galaxies form by dry mergers?

    CERN Document Server

    Scarlata, C; Lilly, S J; Feldmann, R; Kampczyk, P; Renzini, A; Cimatti, A; Halliday, C; Daddi, E; Sargent, M T; Koekemoer, A; Scoville, N; Kneib, J P; Leauthaud, A; Massey, R; Rhodes, J; Tasca, L; McCracken, H J; Mobasher, B; Taniguchi, Y; Thompson, D; Ajiki, M; Aussel, H; Murayama, T; Sanders, D B; Sasaki, S; Shioya, Y; Takahashi, M

    2007-01-01

    ABRIDGED: We study the evolution since z~1 of the rest-frame B luminosity function of the early-type galaxies (ETGs) in ~0.7 deg^2 in the COSMOS field. In order to identify ALL progenitors of local ETGs we construct the sample of high-z galaxies using two complementary criteria: (i) A morphological selection based on the Zurich Estimator of Structural Types, and (ii) A photometric selection based on the galaxy properties in the (U-V)-M_V color-magnitude diagram. We furthermore constrain both samples so as to ensure that the selected progenitors of ETGs are compatible with evolving into systems which obey the mu_B-r_{hl} Kormendy relation. Assuming the luminosity evolution derived from studies of the fundamental plane for high-z ETGs, our analysis shows no evidence for a decrease in the number density of the most massive ETGs out to z~ 0.7: Both the morphologically- and the photometrically-selected sub-samples show no evolution in the number density of bright (~L>2.5L*) ETGs. Allowing for different star format...

  16. EARLY-TYPE HOST GALAXIES OF TYPE Ia SUPERNOVAE. I. EVIDENCE FOR DOWNSIZING

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Yijung; Kim, Young-Lo; Lim, Dongwook; Chung, Chul; Lee, Young-Wook, E-mail: ywlee2@yonsei.ac.kr [Center for Galaxy Evolution Research and Department of Astronomy, Yonsei University, Seoul 03722 (Korea, Republic of)

    2016-03-15

    Type Ia supernova (SN Ia) cosmology provides the most direct evidence for the presence of dark energy. This result is based on the assumption that the lookback time evolution of SN Ia luminosity, after light curve corrections, would be negligible. Recent studies show, however, that the Hubble residual (HR) of SN Ia is correlated with the mass and morphology of host galaxies, implying the possible dependence of SN Ia luminosity on host galaxy properties. In order to investigate this more directly, we have initiated a spectroscopic survey for early-type host galaxies, for which population age and metallicity can be more reliably determined from the absorption lines. In this first paper of the series, we present here the results from high signal-to-noise ratio (≳100 per pixel) spectra for 27 nearby host galaxies in the southern hemisphere. For the first time in host galaxy studies, we find a significant (∼3.9σ) correlation between host galaxy mass (velocity dispersion) and population age, which is consistent with the “downsizing” trend among non-host early-type galaxies. This result is rather insensitive to the choice of population synthesis models. Since we find no correlation with metallicity, our result suggests that stellar population age is mainly responsible for the relation between host mass and HR. If confirmed, this would imply that the luminosity evolution plays a major role in the systematic uncertainties of SN Ia cosmology.

  17. Improving Type Ia Supernova Standard Candle Cosmology Measurements Using Observations of Early-Type Host Galaxies

    Science.gov (United States)

    Meyers, Joshua Evan

    Type Ia supernovae (SNe Ia) are the current standard-bearers for dark energy but face several hurdles for their continued success in future large surveys. For example, spectroscopic classification of the myriad SNe soon to be discovered will not be possible, and systematics from uncertainties in dust corrections and the evolution of SN demographics and/or empirical calibrations used to standardize SNe Ia must be studied. Through the identification of low-dust host galaxies and through increased understanding of both the SN - progenitor connections and empirical calibrations, host galaxy information may offer opportunities to improve the cosmological utility of SNe Ia. The first half of this thesis analyzes the sample of SNe Ia discovered by the Hubble Space Telescope (HST) Cluster Supernova Survey augmented with HST-observed SNe Ia in the Great Observatories Origins Deep Survey (GOODS) fields. Correlations between properties of SNe and their host galaxies are examined at high redshift. Using galaxy color and quantitative morphology to determine the red sequence in 25 clusters, a model is developed to distinguish passively evolving early-type galaxies from star-forming galaxies in both clusters and the field. With this approach, 6 early-type cluster member hosts and 11 SN Ia early-type field hosts are identified. For the first time at z > 0.9, the correlation between host galaxy type and the rise and fall time of SN Ia light curves is confirmed. The relatively simple spectral energy distributions of early-type galaxies also enables stellar mass measurements for these hosts. In combination with literature host mass measurements, these measurements are used to show, at z > 0.9, a hint of the correlation between host mass and Hubble residuals reported at lower redshift. By simultaneously fitting cluster galaxy formation histories and dust content to the scatter of the cluster red sequences, it is shown that dust reddening of early-type cluster SN hosts is likely less

  18. The distribution of ionized gas in early-type galaxies

    Science.gov (United States)

    Buson, L. M.; Sadler, E. M.; Zeilinger, W. W.; Bertin, G.; Bertola, F.; Danzinger, J.; Dejonghe, H.; Saglia, R. P.; de Zeeuw, P. T.

    1993-12-01

    We present and discuss H-alpha+(N II) imaging observations of fifteen nearby elliptical and SO galaxies with extended optical emission lines. The morphology of the emitting regions suggests that the ionized gas usually lies in a disk which is often geometrically decoupled from the stellar body, as expected in a triaxial galaxy. The presence of a gaseous disk makes these galaxies suitable for testing their gravitational field in a straightforward way. The presence of dust in many of the disks, together with the observed morphological properties, suggests that the ionized gas in most of these galaxies is more closely associated with the cold Interstellar Medium (ISM) than with the hot X-ray component. The mass of ionized gas in the galaxies studied here is typically 10-100 times that in a 'normal' early-type galaxy of similar optical luminosity. These appear to be galaxies where an unusually high fraction of the cold gas has been ionized, rather than unusually gas-rich systems in an overall sense. The extra ionizing source may be related to an active nucleus, since the continuum radio emission from these galaxies is typically 10-15 times more powerful than in 'normal' ellipticals of the smae optical luminosity.

  19. Stellar haloes in massive early-type galaxies

    Science.gov (United States)

    Buitrago, F.

    2017-03-01

    The Hubble Ultra Deep Field (HUDF) opens up an unique window to witness galaxy assembly at all cosmic distances. Thanks to its extraordinary depth, it is a privileged tool to beat the cosmological dimming, which affects any extragalactic observations and has a very strong dependence with redshift (1 +z)^4. In particular, massive (M_{stellar}>5 × 10^{10} M_⊙) Early Type Galaxies (ETGs) are the most interesting candidates for these studies, as they must grow in an inside-out fashion developing an extended stellar envelope/halo that accounts for their remarkable size evolution (˜5 times larger in the nearby Universe than at z=2-3). To this end we have analysed the 6 most massive ETGs at z careful data reduction and the exhaustive treatment of the Point Spread Function (PSF), we are able to trace the galaxy surface brightness profiles up to the same levels as in the local Universe but this time at = 0.65 (31 mag arcsec^{-2} in all 8 HST bands, ˜ 29 mag arcsec^{-2} restframe or beyond 25 effective radii). This fact enables us to investigate the galactic outskirts or stellar haloes at a previously unexplored era, characterising their light and mass profiles, colors and for the first time the amount of mass in ongoing mergers.

  20. Early identification of Type I supernova light curves

    CERN Document Server

    Arnett, W David; Matheson, Thomas

    2016-01-01

    We compare analytic light curves for SNIabc supernovae with recent high quality data from (1)) SN2011fe \\citep{sn2011fe}, (2) KSN2011b \\citep{keplersn}, (3) the Palomar Transient Factory (PTF) and the La Silla-QUEST variability survey (LSQ) \\citep{firth}, and (4) a type Ib, SN2008D \\citep{modjaz,soderberg}. We establish a reasonable bolometric conversion between Kepler supernovae and SN2011fe, a crude but instructive one for SN2008D, and discuss the implications of the smoothness of the light-curve for KSN2011b, as well as the meaning of the deviation of early luminosity from $t^2$ behavior. The good agreement of the analytic light curves (which necessarily assume mixing and which can reproduce the Phillips relation) and the observations of highest cadence and stability, are consistent with the occurrence of significant large-scale mixing during the explosion, possibly due to 3D effects (e.g., Rayleigh-Taylor and Richtmeyer-Meshkov instabilities) and consistent with spectrapolarimetry \\citep{amber}. We illust...

  1. Origin of the Lyman excess in early-type stars

    CERN Document Server

    Cesaroni, R; Beltrán, M T; Molinari, S; Olmi, L; Treviño-Morales, S P

    2016-01-01

    Ionized regions around early-type stars are believed to be well-known objects, but until recently, our knowledge of the relation between the free-free radio emission and the IR emission has been observationally hindered by the limited angular resolution in the far-IR. The advent of Herschel has now made it possible to obtain a more precise comparison between the two regimes, and it has been found that about a third of the young HII regions emit more Lyman continuum photons than expected, thus presenting a Lyman excess. With the present study we wish to distinguish between two scenarios that have been proposed to explain the existence of the Lyman excess: (i) underestimation of the bolometric luminosity, or (ii) additional emission of Lyman-continuum photons from an accretion shock. We observed an outflow (SiO) and an infall (HCO+) tracer toward a complete sample of 200 HII regions, 67 of which present the Lyman excess. Our goal was to search for any systematic difference between sources with Lyman excess and ...

  2. Kinematic and chemical evolution of early-type galaxies

    CERN Document Server

    Ziegler, B L; Böhm, A; Bender, R; Fritz, A; Maraston, C

    2004-01-01

    We investigate in detail 13 early-type field galaxies with 0.2

  3. Stellar population gradients in early-type cluster galaxies

    CERN Document Server

    Rawle, T D; Lucey, J R

    2009-01-01

    We present a study of internal stellar population gradients in early-type cluster galaxies. Using the VLT VIMOS integral field unit, we observed 19 galaxies in the core of the Shapley Supercluster (z = 0.048). The radial trends in nine absorption lines (HdF to Fe5406) were measured to the effective radius for 14 galaxies, from which we derived the gradients in age, total metallicity and alpha-element over-abundance. We combine these with results from 11 galaxies studied in our previous VIMOS work (Rawle et al 2008). We observe a mean metallicity gradient of -0.13 +/- 0.04 per dex and, in common with the findings of previous studies, galaxies with log(sigma) > 2.1 have a sizeable intrinsic scatter in metallicity gradient. The mean log(age/Gyr) gradient is -0.02 +/- 0.06 per dex, although several galaxies have significant positive or negative age gradients. The mean gradient in alpha-element enhancement is -0.10 +/- 0.04 per dex. We find that stellar population gradients are primarily related to the central met...

  4. Dual Halos and Formation of Early-Type Galaxies

    CERN Document Server

    Park, Hong Soo

    2013-01-01

    We present a determination of the two-dimensional shape parameters of the blue and red globular cluster systems (GCSs) in a large number of elliptical galaxies and lenticular galaxies (early-type galaxies, called ETGs). We use a homogeneous data set of the globular clusters in 23 ETGs obtained from the HST/ACS Virgo Cluster Survey. The position angles of both blue and red GCSs show a correlation with those of the stellar light distribution, showing that the major axes of the GCSs are well aligned with those of their host galaxies. However, the shapes of the red GCSs show a tight correlation with the stellar light distribution as well as with the rotation property of their host galaxies, while the shapes of the blue GCSs do much less. These provide clear geometric evidence that the origins of the blue and red globular clusters are distinct and that ETGs may have dual halos: a blue (metal-poor) halo and a red (metal-rich) halo. These two halos show significant differences in metallicity, structure, and kinemati...

  5. Hot Gas Halos in Early-Type Field Galaxies

    CERN Document Server

    Mulchaey, John S

    2010-01-01

    We use Chandra and XMM-Newton to study the hot gas content in a sample of field early-type galaxies. We find that the L_X-L_K relationship is steeper for field galaxies than for comparable galaxies in groups and clusters. The low hot gas content of field galaxies with L_K < L_star suggests that internal processes such as supernovae driven winds or AGN feedback expel hot gas from low mass galaxies. Such mechanisms may be less effective in groups and clusters where the presence of an intragroup or intracluster medium can confine outflowing material. In addition, galaxies in groups and clusters may be able to accrete gas from the ambient medium. While there is a population of L_K < L_star galaxies in groups and clusters that retain hot gas halos, some galaxies in these rich environments, including brighter galaxies, are largely devoid of hot gas. In these cases, the hot gas halos have likely been removed via ram pressure stripping. This suggests a very complex interplay between the intragroup/intracluster ...

  6. Early Life Factors and Type 2 Diabetes Mellitus

    Directory of Open Access Journals (Sweden)

    Xinli Jiang

    2013-01-01

    Full Text Available Type 2 diabetes mellitus (T2DM is a multifactorial disease, and its aetiology involves a complex interplay between genetic, epigenetic, and environmental factors. In recent years, evidences from both human and animal experiments have correlated early life factors with programming diabetes risk in adult life. Fetal and neonatal period is crucial for organ development. Many maternal factors during pregnancy may increase the risk of diabetes of offsprings in later life, which include malnutrition, healthy (hyperglycemia and obesity, behavior (smoking, drinking, and junk food diet, hormone administration, and even stress. In neonates, catch-up growth, lactation, glucocorticoids administration, and stress have all been found to increase the risk of insulin resistance or T2DM. Unfavorable environments (socioeconomic situation and famine or obesity also has long-term negative effects on children by causing increased susceptibility to T2DM in adults. We also address the potential mechanisms that may underlie the developmental programming of T2DM. Therefore, it might be possible to prevent or delay the risk for T2DM by improving pre- and/or postnatal factors.

  7. Early Life Factors and Type 2 Diabetes Mellitus

    Science.gov (United States)

    Jiang, Xinli; Ma, Huijie; Wang, Yan; Liu, Yan

    2013-01-01

    Type 2 diabetes mellitus (T2DM) is a multifactorial disease, and its aetiology involves a complex interplay between genetic, epigenetic, and environmental factors. In recent years, evidences from both human and animal experiments have correlated early life factors with programming diabetes risk in adult life. Fetal and neonatal period is crucial for organ development. Many maternal factors during pregnancy may increase the risk of diabetes of offsprings in later life, which include malnutrition, healthy (hyperglycemia and obesity), behavior (smoking, drinking, and junk food diet), hormone administration, and even stress. In neonates, catch-up growth, lactation, glucocorticoids administration, and stress have all been found to increase the risk of insulin resistance or T2DM. Unfavorable environments (socioeconomic situation and famine) or obesity also has long-term negative effects on children by causing increased susceptibility to T2DM in adults. We also address the potential mechanisms that may underlie the developmental programming of T2DM. Therefore, it might be possible to prevent or delay the risk for T2DM by improving pre- and/or postnatal factors. PMID:24455747

  8. Globular Clusters: DNA of Early-Type galaxies?

    CERN Document Server

    Forte, J C; Faifer, F R; Castelli, A V Smith; Escudero, Carlos; González, N M; Sesto, L A

    2014-01-01

    This paper explores if the mean properties of Early-Type Galaxies (ETG) can be reconstructed from "genetic" information stored in their GCs (i.e., in their chemical abundances, spatial distributions and ages). This approach implies that the formation of each globular occurs in very massive stellar environments, as suggested by some models that aim at explaining the presence of multi-populations in these systems. The assumption that the relative number of globular clusters to diffuse stellar mass depends exponentially on chemical abundance, [Z/H], and the presence of two dominant GC sub-populations blue and red, allows the mapping of low metallicity halos and of higher metallicity (and more heterogeneous) bulges. In particular, the masses of the low-metallicity halos seem to scale up with dark matter mass through a constant. We also find a dependence of the globular cluster formation efficiency with the mean projected stellar mass density of the galaxies within their effective radii. The analysis is based on a...

  9. Fundamental properties of nearby single early B-type stars

    Science.gov (United States)

    Nieva, María-Fernanda; Przybilla, Norbert

    2014-06-01

    Aims: Fundamental parameters of a sample of 26 apparently slowly-rotating single early B-type stars in OB associations and in the field within a distance of ≲400 pc from the Sun are presented and compared to high-precision data from detached eclipsing binaries (DEBs). Together with surface abundances for light elements the data are used to discuss the evolutionary status of the stars in context of the most recent Geneva grid of models for core hydrogen-burning stars in the mass-range ~6 to 18 M⊙ at metallicity Z = 0.014. Methods: The fundamental parameters are derived on the basis of accurate and precise atmospheric parameters determined earlier by us from non-LTE analyses of high-quality spectra of the sample stars, utilising the new Geneva stellar evolution models. Results: Evolutionary masses plus radii and luminosities are determined to better than typically 5%, 10%, and 20% uncertainty, respectively, facilitating the mass-radius and mass-luminosity relationships to be recovered for single core hydrogen-burning objects with a similar precision as derived from DEBs. Good agreement between evolutionary and spectroscopic masses is found. Absolute visual and bolometric magnitudes are derived to typically ~0.15-0.20 mag uncertainty. Metallicities are constrained to better than 15-20% uncertainty and tight constraints on evolutionary ages of the stars are provided. Overall, the spectroscopic distances and ages of individual sample stars agree with independently derived values for the host OB associations. Signatures of mixing with CN-cycled material are found in 1/3 of the sample stars. Typically, these are consistent with the amount predicted by the new Geneva models with rotation. The presence of magnetic fields appears to augment the mixing efficiency. In addition, a few objects are possibly the product of binary evolution. In particular, the unusual characteristics of τ Sco point to a blue straggler nature, due to a binary merger. Conclusions: The accuracy

  10. Early Puberty Linked to Higher Type 2 Diabetes Risk

    Science.gov (United States)

    ... associated with early menarche was still apparent after accounting for adiposity. Around half of the increased risk ... Diabetes Pro: Professional Resources Shop Diabetes » Close nonprofit software

  11. Herschel-ATLAS: Dusty early-type galaxies

    Science.gov (United States)

    Rowlands, K.; Dunne, L.; Maddox, S.

    2015-03-01

    Early-type galaxies (ETGs) are thought to be devoid of dust and star-formation, having formed most of their stars at early epochs. We present the detection of the dustiest ETGs in a large-area blind submillimetre survey with Herschel (H-ATLAS, Eales et al. 2010), where the lack of pre-selection in other bands makes it the first unbiased survey for cold dust in ETGs. The parent sample of 1087 H-ATLAS galaxies in this study have a >= 5σ detection at 250μm, a reliable optical counterpart to the submillimetre source (Smith et al. 2011) and a spectroscopic redshift from the GAMA survey (Driver et al. 2011). Additionally, we construct a control sample of 1052 optically selected galaxies undetected at 250μm and matched in stellar mass to the H-ATLAS parent sample to eliminate selection effects. ETGs were selected from both samples via visual classifications using SDSS images. Further details can be found in Rowlands et al. (2012). Physical parameters are derived for each galaxy using the multiwavelength spectral energy distribution (SED) fitting code of da Cunha, Charlot and Elbaz (2008), Smith et al. 2012, using an energy balance argument. We investigate the differences between the dusty ETGs and the general ETG population, and find that the H-ATLAS ETGs are more than an order of magnitude dustier than the control ETGs. The mean dust mass of the 42 H-ATLAS ETGs is 5.5 × 107M⊙ (comparable to the dust mass of spirals in our sample), whereas the dust mass of the 233 control ETGs inferred from stacking at optical positions on the 250μm map is (0.8 - 4.0) × 106M⊙ for 25-15 K dust. The average star-formation rate of the H-ATLAS ETGs is 1.0 dex higher than that of control ETGs, and the mean r-band light-weighted age of the H-ATLAS ETGs is 1.8 Gyr younger than the control ETGs. The rest-frame NUV - r colours of the H-ATLAS ETGs are 1.0 magnitudes bluer than the control ETGs, and some ETGs may be transitioning from the blue cloud to the red sequence. Some H-ATLAS ETGs

  12. The Early-type Galaxy Population in Abell 2390

    Science.gov (United States)

    Fritz, A.; Ziegler, B. L.

    We present high-quality spectroscopic data of 51 elliptical and lenticular galaxies in the rich cluster A2390 at z=0.23 obtained with MOSCA from the 3.5 m telescope at the Calar Alto Observatory in 7 nights during 2 runs. Our investigation is spanning a wider range in luminosity (M*B+1) than previous spectroscopic studies, which were limited to a small number of the more luminous galaxies. This is only the second cluster at intermediate redshift where such a large sample has been investigated (the other is A2218 at z=0.18, see Ziegler et al. MNRAS 2001, in press, astro-ph/0103475). Analysis of absorption line strengths lets us explore the evolution of galaxies in age and metallicity. Velocity dispersions (σ) are determined to study the slope, scatter and zeropoint offset of the Faber-Jackson and Mg-σ relations. In combination with morphological and structural parameters of a subsample of galaxies observed with HST, we also investigate the evolution of the Fundamental Plane. The overall sample is large enough to explore statistically significant sub-populations like S0 or Balmer-line enhanced galaxies and look for variations in early-type galaxy evolution as a function of distance from the cluster center. In addition to studying the evolution with respect to local clusters, we also investigate the variations in slope, scatter and zeropoint of the above relations between the equally rich clusters A2218 and A2390 at z=0.2.

  13. Early-type Host Galaxies of Type Ia Supernovae. I. Evidence for Downsizing

    CERN Document Server

    Kang, Yijung; Lim, Dongwook; Chung, Chul; Lee, Young-Wook

    2016-01-01

    Type Ia supernova (SN Ia) cosmology provides the most direct evidence for the presence of dark energy. This result is based on the assumption that the look-back time evolution of SN Ia luminosity, after light-curve corrections, would be negligible. Recent studies show, however, that the Hubble residual (HR) of SN Ia is correlated with the mass and morphology of host galaxies, implying the possible dependence of SN Ia luminosity on host galaxy properties. In order to investigate this more directly, we have initiated spectroscopic survey for the early-type host galaxies, for which population age and metallicity can be more reliably determined from the absorption lines. As the first paper of the series, here we present the results from high signal-to-noise ratio (>100 per pixel) spectra for 27 nearby host galaxies in the southern hemisphere. For the first time in host galaxy studies, we find a significant (~3.9sigma) correlation between host galaxy mass (velocity dispersion) and population age, which is consiste...

  14. The early noncoding region of human papillomavirus type 16 is regulated by cytoplasmic polyadenylation factors

    DEFF Research Database (Denmark)

    Glahder, Jacob-Andreas Harald; Kristiansen, Karen; Durand, Marjorie

    2010-01-01

    All human papillomavirus type 16 (HPV-16) early mRNAs are polyadenylated at the poly(A) signal within the early 3' untranslated region (3'UTR). The 3'end of the early E5 open reading frame and the 3'UTR of HPV-16 is very AU-rich, with five regions similar to cytoplasmic polyadenylation elements (...

  15. X-ray Binaries in Early Type Galaxies and the Globular Cluster Connection

    NARCIS (Netherlands)

    Maccarone, T.J.; Kundu, A.; Zepf, S.E.; Puzia, T.H.; Tovmassian, G.; Sion, E.

    2004-01-01

    We summarize the key observations made in recent observations of X-ray sources in early-type galaxies. Typically about half of the X-ray binaries in early-type galaxies are in globular clusters, they are preferentially found in metal rich globular clusters, and there is no indication that cluster

  16. The dustier early-type galaxies deviate from late-type galaxies' scaling relations

    CERN Document Server

    Lianou, Sophia; Madden, Suzanne; Barmby, Pauline

    2016-01-01

    Several dedicated surveys focusing on early-type galaxies (ETGs) reveal that significant fractions of them are detectable in all interstellar medium phases studied to date. We select ETGs from the Herschel Reference Survey that have both far-infrared Herschel and either HI or CO detection (or both). We derive their star formation rates (SFR), stellar masses and dust masses via modelling their spectral energy distributions. We combine these with literature information on their atomic and molecular gas properties, in order to relate their star formation, total gas mass and dust mass on global scales. The ETGs deviate from the dust mass-SFR relation and the Schmidt-Kennicutt relation that SDSS star forming galaxies define: compared to SDSS galaxies, ETGs have more dust at the same SFR, or less SFR at the same dust mass. When placing them in the M*-SFR plane, ETGs show a much lower specific SFR as compared to normal star-forming galaxies. ETGs show a large scatter compared to the Schmidt-Kennicutt relation found ...

  17. Early insulin therapy in patients with type 2 diabetes mellitus

    African Journals Online (AJOL)

    Type 2 diabetes mellitus (T2DM) is a progressive disease characterised by beta cell ... The traditional approach to the management of T2DM is lifestyle change, diet, ... Physiologically, fasting glucose is controlled by endogenous basal.

  18. [Type 1 diabetes mellitus. Early detection and prevention].

    Science.gov (United States)

    Hummel, M; Achenbach, P

    2015-05-01

    Type 1 diabetes is the most common autoimmune disease in children and adolescents, with a rising incidence worldwide. Despite improvements in insulin therapy, in many cases complications cannot be avoided and mortality is increased. Therefore, the development of effective prevention strategies is an important medical but also economic goal. Exact prediction of the disease is necessary for prevention studies, and type 1 diabetes can be predicted very accurately with genetic and humoral markers. Primary prevention in genetically predisposed individuals is initiated before diabetes-associated autoantibodies occur. Secondary prevention aims to arrest the progression to type 1 diabetes in autoantibody-positive subjects. Some prevention studies show encouraging results.

  19. Academic Performance and Type of Early Childhood Care

    DEFF Research Database (Denmark)

    Datta Gupta, Nabanita; Simonsen, Marianne

    2015-01-01

    This is one of the few studies that estimates the effects of type of childhood care on academic achievement at higher grade levels by linking day care registers and educational registers. We use entire birth cohorts of ethnic Danish children, enrolled in either center based day care or family day...... care at age 2. Exploiting variation across municipalities in guaranteed access to center based care as an instrument for type of care our results show that center based day care improves grades in Danish language in the final year of compulsory school with around 0.2 standard deviations....

  20. Academic Performance and Type of Early Childhood Care

    DEFF Research Database (Denmark)

    Datta Gupta, Nabanita; Simonsen, Marianne

    2015-01-01

    This is one of the few studies that estimates the effects of type of childhood care on academic achievement at higher grade levels by linking day care registers and educational registers. We use entire birth cohorts of ethnic Danish children, enrolled in either center based day care or family day...

  1. ALFALFA HI Content and Star Formation in Virgo Cluster Early-Type Dwarfs

    CERN Document Server

    Koopmann, R A; Haynes, M P; Brosch, N

    2009-01-01

    The ALFALFA (Arecibo Legacy Fast ALFA) blind survey is providing a census of HI in galaxies of all types in a range of environments. Here we report on ALFALFA results for Virgo Cluster early-type dwarfs between declinations of 4 and 16 degrees. Less than 2% of the Virgo early-type dwarf population is detected, compared to 70-80% of the Im/BCD dwarf population. Most of the dwarfs detected in HI show evidence for ongoing or recent star formation. Early-type galaxies with HI tend to be located in the outer regions of the cluster and to be brighter. Early-type dwarfs with HI may be undergoing morphological transition due to cluster environmental effects.

  2. Variable Low-Mass X-ray Binaries in Early-Type Galaxies

    CERN Document Server

    Sivakoff, Gregory R; Juett, Adrienne M; Sarazin, Craig L; Irwin, Jimmy A

    2007-01-01

    As the Chandra X-ray Observatory mission matures, increasing numbers of nearby galaxies are being observed multiple times, sampling the variability of extragalactic X-ray binaries on timescales extending from seconds to years. We present results on luminous low-mass X-ray binaries from several early-type galaxies. We show that instantaneous LMXB luminosity functions of early-type galaxies do not significantly change between observations; a relatively low fraction of sources are strongly variable on <~ 5 yr timescales. We discuss the implications that a relatively small number of transient LMXBs are being discovered in early-type galaxies.

  3. Early Recognition of H-Type Tracheoesophageal Fistula

    Directory of Open Access Journals (Sweden)

    Muhammad Riazulhaq

    2012-02-01

    Full Text Available Tracheoesophageal fistula (TEF without associated esophageal atresia (EA is a rare congenital anomaly. Diagnosis in neonatal period is usually not made and most of the patients are treated as cases of pneumonia. A case of H-type of tracheoesophageal fistula, diagnosed within 24 hours of delivery based upon choking and cyanosis on first trial of feed, is being reported. Diagnosis was confirmed with contrast esophagram. Through cervical approach fistula was repaired and baby had uneventful post operative outcome.

  4. Categorically distinct types of receptive fields in early visual cortex.

    Science.gov (United States)

    Talebi, Vargha; Baker, Curtis L

    2016-05-01

    In the visual cortex, distinct types of neurons have been identified based on cellular morphology, response to injected current, or expression of specific markers, but neurophysiological studies have revealed visual receptive field (RF) properties that appear to be on a continuum, with only two generally recognized classes: simple and complex. Most previous studies have characterized visual responses of neurons using stereotyped stimuli such as bars, gratings, or white noise and simple system identification approaches (e.g., reverse correlation). Here we estimate visual RF models of cortical neurons using visually rich natural image stimuli and regularized regression system identification methods and characterize their spatial tuning, temporal dynamics, spatiotemporal behavior, and spiking properties. We quantitatively demonstrate the existence of three functionally distinct categories of simple cells, distinguished by their degree of orientation selectivity (isotropic or oriented) and the nature of their output nonlinearity (expansive or compressive). In addition, these three types have differing average values of several other properties. Cells with nonoriented RFs tend to have smaller RFs, shorter response durations, no direction selectivity, and high reliability. Orientation-selective neurons with an expansive output nonlinearity have Gabor-like RFs, lower spontaneous activity and responsivity, and spiking responses with higher sparseness. Oriented RFs with a compressive nonlinearity are spatially nondescript and tend to show longer response latency. Our findings indicate multiple physiologically defined types of RFs beyond the simple/complex dichotomy, suggesting that cortical neurons may have more specialized functional roles rather than lying on a multidimensional continuum.

  5. Homogeneity of early-type galaxies across clusters

    CERN Document Server

    Andreon, S

    2003-01-01

    We studied the homogeneity, across clusters, of the color of the red sequence (the intercept of the color--magnitude relation) of 158 clusters and groups detected in the Early Data Release of the Sloan Digital Sky Survey (EDR-SDSS) in the redshift range 0.062) or else their star formation is universally delayed with preservation of a small spread in age formation. The latter possibility is ruled out by the mere existence of galaxies at high redshift. While the old age of ellipticals was already been claimed for a small heterogeneous collection of clusters, most of which are rich ones, we found that it holds for ten to one hundred large sample, representative of all clusters and groups detected on the EDR-SDSS. Hence we suggest the possible universality of the color of the galaxies on the red sequence. The observed red sequence color does not depend on cluster/group richness at a level of 0.02 mag, while a ~0.23 mag effect is expected according to the hierarchical prediction. Therefore, the stellar population ...

  6. Weak magnetic fields in early-type stars: failed fossils

    CERN Document Server

    Braithwaite, Jonathan

    2012-01-01

    Weak magnetic fields have recently been detected in Vega and Sirius. Here, we explore the possibility that these fields are the remnants of some field inherited or created during or shortly after star formation and, unlike true fossil fields, are still evolving as we observe them. The timescale of this evolution is given in terms of the Alfven timescale and the rotation frequency by tau_evol ~ tau_A^2 Omega, which would be comparable to the age of the star. It is shown that it is likely that all intermediate- and high-mass stars contain fields of at least the order of the strength found so far in Vega and Sirius. Faster rotators are expected to have stronger magnetic fields. Stars may experience an increase in field strength during their early main-sequence, but for most of their lives field strength will decrease slowly. The length scale of the magnetic structure on the surface may be small in very young stars but should quickly increase to at least very approximately a fifth of the stellar radius.

  7. Digging for Formational Clues in the Halos of Early-type Galaxies

    CERN Document Server

    Romanowsky, Aaron J

    2010-01-01

    Many of the fundamental properties of early-type galaxies (ellipticals and lenticulars) can only be accessed by venturing beyond their oft-studied centers into their large-radius halo regions. Advances in observations of kinematical tracers allow early-type halos to be increasingly well probed. This review focuses on recent findings on angular momentum and dark matter content, and discusses some possible implications for galaxy structure and formation.

  8. Early-type Eclipsing Binaries at Intermediate Orbital Periods

    CERN Document Server

    Moe, Maxwell

    2015-01-01

    We analyze 221 eclipsing binaries (EBs) in the Large Magellanic Cloud with B-type main-sequence (MS) primaries ($M_1$ $\\approx$ 4 - 14 M$_{\\odot}$) and orbital periods $P$ = 20 - 50 days that were photometrically monitored by the Optical Gravitational Lensing Experiment. We utilize our three-stage automated pipeline to (1) classify all 221 EBs, (2) fit physical models to the light curves of 130 detached well-defined EBs from which unique parameters can be determined, and (3) recover the intrinsic binary statistics by correcting for selection effects. We uncover two statistically significant trends with age. First, younger EBs tend to reside in dustier environments with larger photometric extinctions, an empirical relation that can be implemented when modeling stellar populations. Second, younger EBs generally have large eccentricities. This demonstrates that massive binaries at moderate orbital periods are born with a Maxwellian "thermal" orbital velocity distribution, which indicates they formed via dynamica...

  9. Syndecan-1 and E-cadherin expression in differentiated type of early gastric cancer

    Institute of Scientific and Technical Information of China (English)

    Mei-Fang Huang; You-Qing Zhu; Zhi-Fen Chen; Jun Xiao; Xin Huang; Yong-Yan Xiong; Gui-Fang Yang

    2005-01-01

    AIM: To elucidate the role and alterations of syndecan-1 and E-cadherin expression in different cellular phenotypes of differentiated-type gastric cancers (DGCs), METHODS: A total of 120 DGCs at an early stage, andtheir adjacent mucosa, were studied both by immunohistochemistry. Syndecan-1 and E-cadherin were assessed by immunohistochemical staining with anti-syndecan-1 and anti-E-cadherin antibodies, respectively. Based on immunohistochemistry, DGCs and their surrounding mucosa were divided into four types: gastric type (G-type),ordinary type (O-type), complete-intestinal type (CI-type),and null type (N-type).RESULTS: Syndecan-1 expression was significantly lower in G-type cancers (29.4%) than in O-type (79.6%) and CI-type cancers (90%) (P<0.05, respectively), but E-cadherin did not show this result. In addition, syndecan-1 expression was significantly reduced in DGCs comprised partly of poorly differentiated adenocarcinoma or signet-ring cell carcinoma, compared to DGCs demonstrating papillary and/or tubular adenocarcinoma (P<0.05). G-type intestinal metaplasia (IM) surrounding the tumors was observed in 23.8% of G-type, 4.9% of O-type, and 6.7% of CI-type cancers (P<0.05; G-type vs O-type). Reduction of syndecan-1 expression was significant in G-type IM (25%) compared to non-G-type IM (75%; P<0.05).CONCLUSION: Loss of syndecan-1 plays a role in the growth of G-type cancers of DGCs at an early stage, and the reduction of syndecan-1 expression in IM surrounding the tumors may influence the growth of G-type cancer.

  10. Forming an Early O-type Star Through Gas Accretion?

    CERN Document Server

    Zapata, Luis A; HO, Paul; Schilke, Peter; Garrod, Robin T; Rodriguez, Luis F; Menten, Karl

    2007-01-01

    We present high angular resolution ($\\sim$ 3$''$) and sensitive 1.3 mm continuum, cyanogen (CN) and vinyl cyanide (C$_2$H$_3$CN) line observations made with the Submillimeter Array (SMA) toward one of most highly obscured objects of the W51 IRS2 region, W51 North. We find that the CN line exhibits a pronounced inverse P-Cygni profile indicating that the molecular gas is infalling inwards this object with a mass accretion rate between 4 and 7 $\\times$ 10$^{-2}$ M$_\\odot$ yr$^{-1}$. The C$_2$H$_3$CN traces an east-west rotating molecular envelope that surrounds either a single obscured (proto)star with a kinematic mass of 40 M$_{\\odot}$ or a small central cluster of B-type stars and that is associated with a compact high velocity bipolar outflow traced by H$_2$O masers and SiO molecular emission. We thus confirm that the W51 North region is part of the growing list of young massive star forming regions that have been associated with infalling motions and with large mass accretion rates ($\\sim$ 10$^{-2}$ -- 10$^...

  11. The outer disks of early-type galaxies. I. Surface-brightness profiles of barred galaxies

    NARCIS (Netherlands)

    Erwin, Peter; Pohlen, Michael; Beckman, John E.

    2008-01-01

    We present a study of 66 barred, early-type (S0-Sb) disk galaxies, focused on the disk surface brightness profile outside the bar region, with the aim of throwing light on the nature of Freeman type I and II profiles, their origins, and their possible relation to disk truncations. This paper discuss

  12. The outer disks of early-type galaxies. I. Surface-brightness profiles of barred galaxies

    NARCIS (Netherlands)

    Erwin, Peter; Pohlen, Michael; Beckman, John E.

    We present a study of 66 barred, early-type (S0-Sb) disk galaxies, focused on the disk surface brightness profile outside the bar region, with the aim of throwing light on the nature of Freeman type I and II profiles, their origins, and their possible relation to disk truncations. This paper

  13. Shape Evolution of Massive Early-Type Galaxies: Confirmation of Increased Disk Prevalence at z>1

    CERN Document Server

    Chang, Yu-Yen; Rix, Hans-Walter; Wuyts, Stijn; Zibetti, Stefano; Ramkumar, Balasubramanian; Holden, Bradford P

    2012-01-01

    We use high-resolution K-band VLT/HAWK-I imaging over 0.25 square degrees to study the structural evolution of massive early-type galaxies since z~1. Mass-selected samples, complete down to log(M/M_sun)~10.7 such that `typical' L* galaxies are included at all redshifts, are drawn from pre-existing photometric redshift surveys. We then separated the samples into different redshift slices and classify them as late- or early-type galaxies on the basis of their specific star-formation rate. Axis-ratio measurements for the ~400 early-type galaxies in the redshift range 0.61 are, on average, flatter than at z11.3) are the roundest, with a pronounced lack among them of galaxies that are flat in projection. Merging is a plausible mechanism that can explain both results: at all epochs merging is required for early-type galaxies to grow beyond log(M/M_sun)~11.3, and all early types over time gradually and partially loose their disk-like characteristics.

  14. The effect of color type on early wound healing in farmed mink (Neovison vison)

    DEFF Research Database (Denmark)

    Jespersen, A.; Jensen, H. E.; Agger, J. F.

    2017-01-01

    Background: Individual differences of mink, including color type, are speculated to affect the course of wound healing, thereby impacting wound assessment and management on the farms, as well as the assessment of wounds in forensic cases. In this study, we examined the effect of color type on early...... wound healing in farmed mink. Full thickness excisional wounds (2 x 2 cm) were made on the back in 18 mink of the color types Brown, Silverblue and Blue Iris. Gross and microscopic pathology of the wounds was evaluated 2 days post-wounding together with degree of wound size reduction, presence...... amyloid A from day 0 to day 2 in all color types. Conclusions: We have described differences in early wound healing between mink of the color types Brown, Silverblue and Blue Iris by use of an experimental wound model in farmed mink. The most pronounced difference pertained to the degree of wound size...

  15. Probing Spin-Orbit Misalignment Processes Around Early-Type Stars

    Science.gov (United States)

    Ahlers, Johnathon; Barnes, Jason W.

    2016-10-01

    Planets in early-type systems seem to frequently misalign from their host star's spin axis. These spin-orbit misaligned systems challenge conventional planet-formation theories because planets probably do not form with initially misaligned orbits -- their angular momenta must be conserved with the stellar nursery in which they formed. In such a case, planets must migrate to their misaligned positions. However, very few transiting exoplanets have had their spin-orbit alignment angles measured. Our model constrains spin-orbit alignment angles via photometry and asteroseismology while accounting for the brightness effects of stellar variability and rapid rotation that commonly occur in early-type stars, making the analysis of hundreds of Kepler transit light curves possible for the first time. We will employ these techniques to probe spin-orbit misalignment theories by empirically testing the spin-orbit state of exoplanets orbiting early-type stars.

  16. Forming Early-type Galaxies in Groups Prior to Cluster Assembly

    CERN Document Server

    Kautsch, Stefan J; Soto, Christian A; Tran, Kim-Vy H; Zaritsky, Dennis; Moustakas, John

    2008-01-01

    We study a unique proto-cluster of galaxies, the supergroup SG1120-1202. We quantify the degree to which morphological transformation of cluster galaxies occurs prior to cluster assembly in order to explain the observed early-type fractions in galaxy clusters at z=0. SG1120-1202 at z~0.37 is comprised of four gravitationally bound groups that are expected to coalesce into a single cluster by z=0. Using HST ACS observations, we compare the morphological fractions of the supergroup galaxies to those found in a range of environments. We find that the morphological fractions of early-type galaxies (~60 %) and the ratio of S0 to elliptical galaxies (0.5) in SG1120-1202 are very similar to clusters at comparable redshift, consistent with pre-processing in the group environment playing the dominant role in establishing the observed early-type fraction in galaxy clusters.

  17. Prediction of preeclampsia in type 1 diabetes in early pregnancy by clinical predictors

    DEFF Research Database (Denmark)

    Vestgaard, Marianne; Sommer, Miriam Colstrup; Ringholm, Lene

    2017-01-01

    PURPOSE: The purpose of this study is to evaluate the prevalence and possible clinical predictors of preeclampsia present in early pregnancy among women with type 1 diabetes. METHODS: A systematic search of PubMed was conducted in April 2017. Inclusion criteria were largely unselected cohort......, including at least 100 women with type 1 diabetes, dealing with either the prevalence of preeclampsia or possible clinical predictors of preeclampsia identified in early pregnancy. RESULTS: Based on 11,518 pregnancies in 11 articles, the prevalence of preeclampsia in women with type 1 diabetes was 17%, five...... to six times more than in the background population. In early pregnancy, the following clinical predictors were associated with increased prevalence of preeclampsia: diabetic nephropathy (OR 3.7-23.5), microalbuminuria (OR 3.8-11.7), diabetic retinopathy (OR 1.9-2.9) and pre-existing hypertension (OR 3...

  18. Revealing the nature of star forming blue early-type galaxies at low redshift

    CERN Document Server

    George, Koshy

    2015-01-01

    Context: Star forming early-type galaxies with blue optical colours at low redshift can be used to test our current understanding of galaxy formation and evolution. Aims: We want to reveal the fuel and triggering mechanism for star formation in these otherwise passively evolving red and dead stellar systems. Methods: We undertook an optical and ultraviolet study of 55 star forming blue early-type galaxies, searching for signatures of recent interactions that could be driving the molecular gas into the galaxy and potentially triggering the star formation. Results: We report here our results on star forming blue early-type galaxies with tidal trails and in close proximity to neighbouring galaxies that are evidence of ongoing or recent interactions between galaxies. There are 12 galaxies with close companions with similar redshifts, among which two galaxies are having ongoing interactions that potentially trigger the star formation. Two galaxies show a jet feature that could be due to the complete tidal disrupti...

  19. Finslerian MOND versus the Strong Gravitational Lensing of the Early-type Galaxies

    CERN Document Server

    Chang, Zhe; Li, Xin; Lin, Hai-Nan; Wang, Sai

    2013-01-01

    The gravitational lensing of Bullet Clusters and early-type galaxies pose serious challenges on the validity of MOND. Recently, Finslerian MOND, a generalization of MOND in the framework of Finsler gravity, has been proposed to explain the mass discrepancy problem of Bullet Cluster 1E 0657\\ 558. In this paper, we check the validity of the Finslerian MOND in describing the strong gravitational lensing of early-type galaxies. The investigation on ten strong lenses of the CASTLES samples shows that there is no strong evidence for the existence of dark matter.

  20. Global X-ray emission and central properties of early type galaxies

    CERN Document Server

    Pellegrini, S

    1999-01-01

    Hubble Space Telescope observations revealed that the central surface brightness profiles of early type galaxies can be divided into two types: "core" profiles and featureless power law profiles. On the basis of this and previous results, early type galaxies have been grouped into two families: coreless galaxies, which are also rapidly rotating, nearly isotropic spheroids, and with disky isophotes, and core galaxies, which are slowly rotating and boxy-distorted. Here I investigate the relationship between global X-ray emission and shape of the inner surface brightness profile, for a sample of 59 early type galaxies. I find a clear dicothomy also in the X-ray properties, in the sense that core galaxies span the whole observed range of Lx values, while power law galaxies are confined below log Lx (erg/s)=41. Moreover, the relation between Lx and the shape of the central profile is the strongest among the relations of Lx with the basic properties characterizing the two families of early type galaxies. So, a glob...

  1. Dark-Matter Content of Early-Type Galaxies with Planetary Nebulae

    NARCIS (Netherlands)

    Napolitano, N.R.; Romanowsky, A.J.; Coccato, L; Capaccioli, M.; Douglas, N.G.; Noordermeer, E.; Merrifield, M.R.; Kuijken, K.; Arnaboldi, M.; Gerhard, O.; Freeman, K.C.; De Lorenzi, F.; Das, P.

    2007-01-01

    Abstract. We examine the dark matter properties of nearby early-type galaxies using plane- tary nebulae (PNe) as mass probes. We have designed a specialised instrument, the Planetary Nebula Spectrograph (PN.S) operating at the William Herschel telescope, with the purpose of measuring PN velocities

  2. Early Detection and Treatment of Type 2 Diabetes Reduce Cardiovascular Morbidity and Mortality

    DEFF Research Database (Denmark)

    Herman, William H; Ye, Wen; Griffin, Simon J

    2015-01-01

    OBJECTIVE To estimate the benefits of screening and early treatment of type 2 diabetes compared with no screening and late treatment using a simulation model with data from the ADDITION-Europe study. RESEARCH DESIGN AND METHODS We used the Michigan Model, a validated computer simulation model, an...

  3. Genetic correlates of early accelerated infant growth associated with juvenile-onset type 1 diabetes

    NARCIS (Netherlands)

    Kharagjitsingh, A.V.; de Ridder, M.A.J.; Alizadeh, B.Z.; Veeze, H.J.; Bruining, G.J.; Roep, B.O.; Koeleman, Bobby P.C.

    2012-01-01

    Objective: We previously showed that accelerated growth predisposing to development of childhood-onset type 1 diabetes (T1D) is restricted to the first year after birth. We assessed whether this phenomenon of increased early growth is associated with variants of two genes, insulin-like growth factor

  4. Structural Evolution of Early-type Galaxies to z=2.5 in CANDELS

    CERN Document Server

    Chang, Yu-Yen; Rix, Hans-Walter; Holden, Bradford; Bell, Eric F; McGrath, Elizabeth J; Wuyts, Stijn; Häußler, Boris; Barden, Marco; Faber, S M; Mozena, Mark; Ferguson, Henry C; Guo, Yicheng; Galametz, Audrey; Grogin, Norman A; Kocevski, Dale D; Koekemoer, Anton M; Dekel, Avishai; Huang, Kuang-Han; Hathi, Nimish P; Donley, Jennifer

    2013-01-01

    Projected axis ratio measurements of 880 early-type galaxies at redshifts 11 early-type galaxies show a variety of intrinsic shapes; even at a fixed mass, the projected axis ratio distributions cannot be explained by random projection of a set of galaxies with very similar intrinsic shapes. However, a two-population model for the intrinsic shapes, consisting of a triaxial, fairly round population, combined with a flat (c/a~0.3) oblate population, adequately describes the projected axis ratio distributions of both present-day and z>1 early-type galaxies. We find that the proportion of oblate vs. triaxial galaxies depends both on the galaxies stellar mass, and - at a given mass - on redshift. For present-day and z1 this trend is much weaker over the mass range explored here (10^101, compared to 0.20+-0.02 at z~0.1. In contrast, the oblate fraction among low-mass early-type galaxies (log(M*/M_sun)1 to 0.72+-0.06 at z=0. [Abridged

  5. THE SLACS SURVEY. VIII. THE RELATION BETWEEN ENVIRONMENT AND INTERNAL STRUCTURE OF EARLY-TYPE GALAXIES

    NARCIS (Netherlands)

    Treu, Tommaso; Gavazzi, Raphael; Gorecki, Alexia; Marshall, Philip J.; Koopmans, Leon V. E.; Bolton, Adam S.; Moustakas, Leonidas A.; Burles, Scott

    2009-01-01

    We study the relation between the internal structure of early-type galaxies and their environment using 70 strong gravitational lenses from the SLACS Survey. The Sloan Digital Sky Survey (SDSS) database is used to determine two measures of overdensity of galaxies around each lens-the projected

  6. Children's Communication and Socialization Skills by Types of Early Education Experiences

    Science.gov (United States)

    Lee, Joohi; Fox, Jill

    2009-01-01

    This study is an investigation of children's communication skills and socialization by the types of their early education experiences (e.g., child care centers, private schools, public schools, home, or other). A total of 244 children (average age: 61 months) and their parents participated in this study. According to the results of this study,…

  7. Discovery of a magnetic field in the early B-type star σ Lupi

    NARCIS (Netherlands)

    Henrichs, H.F.; Kolenberg, K.; Plaggenborg, B.; Marsden, S.C.; Waite, I.A.; Landstreet, J.D.; Wade, G.A.; Grunhut, J.H.; Oksala, M.E.

    2012-01-01

    Context. Magnetic early B-type stars are rare. Indirect indicators are needed to identify them before investing in time-intensive spectropolarimetric observations. Aims. We use the strongest indirect indicator of a magnetic field in B stars, which is periodic variability of ultraviolet (UV) stellar

  8. Kinematic properties of early-type galaxy haloes using planetary nebulae

    NARCIS (Netherlands)

    Coccato, L.; Gerhard, O.; Arnaboldi, M.; Das, P.; Douglas, N. G.; Kuijken, K.; Merrifield, M. R.; Napolitano, N. R.; Noordermeer, E.; Romanowsky, A. J.; Capaccioli, M.; Cortesi, A.; De Lorenzi, F.; Freeman, K. C.

    2009-01-01

    We present new planetary nebulae (PNe) positions, radial velocities and magnitudes for six early-type galaxies obtained with the Planetary Nebulae Spectrograph (PNS), along with derived two-dimensional velocity and velocity dispersion fields, and the alpha parameters (i.e. the number of PNe per unit

  9. Rigidity in Gender-Typed Behaviors in Early Childhood: A Longitudinal Study of Ethnic Minority Children

    Science.gov (United States)

    Halim, May Ling; Ruble, Diane; Tamis-LeMonda, Catherine; Shrout, Patrick E.

    2013-01-01

    A key prediction of cognitive theories of gender development concerns developmental trajectories in the relative strength or rigidity of gender typing. To examine these trajectories in early childhood, 229 children (African American, Mexican American, and Dominican American) were followed annually from age 3 to 5 years, and gender-stereotypical…

  10. Genetic correlates of early accelerated infant growth associated with juvenile-onset type 1 diabetes

    NARCIS (Netherlands)

    Kharagjitsingh, Av; de Ridder, Maj; Alizadeh, Bz; Veeze, Hj; Bruining, Gj; Roep, Bo; Koeleman, Bobby Pc

    2012-01-01

    OBJECTIVE: We previously showed that accelerated growth predisposing to development of childhood-onset type 1 diabetes (T1D) is restricted to the first year after birth. We assessed whether this phenomenon of increased early growth is associated with variants of two genes, insulin-like growth factor

  11. An extensive catalogue of early-type galaxies in the nearby universe

    CERN Document Server

    Dabringhausen, J

    2016-01-01

    We present a catalogue of 1715 early-type galaxies from the literature, spanning the luminosity range from faint dwarf spheroidal galaxies to giant elliptical galaxies. The aim of this catalogue is to be one of the most comprehensive and publicly available collections of data on early-type galaxies. The emphasis in this catalogue lies on dwarf elliptical galaxies, for which some samples with detailed data have been published recently. For almost all of the early-type galaxies included in it, this catalogue contains data on their locations, distances, redshifts, half-light radii, the masses of their stellar populations and apparent magnitudes in various passbands. Data on metallicity and various colours are available for a majority of the galaxies presented here, including many of the rather faint early-type galaxies in the Local group. The data on magnitudes, colours, metallicities and masses of the stellar populations is supplemented with entries that are based on fits to data from simple stellar population ...

  12. The kinematic properties of dwarf early-type galaxies in the Virgo cluster

    NARCIS (Netherlands)

    Toloba, E.; Boselli, A.; Peletier, R. F.; Gorgas, J.; Zapatero Osorio, M.R.; Gorgas, J.; Maíz Apellániz, J.; Pardo, J.R.; Gil de Paz, A.

    2011-01-01

    We present new medium resolution kinematic data for a sample of 21 dwarf early-type galaxies (dEs) mainly in the Virgo cluster. These data are used to study the origin of dEs inhabiting clusters. Within them we detect two populations: half of the sample (52%) are rotationally supported and the other

  13. THE SLACS SURVEY. VIII. THE RELATION BETWEEN ENVIRONMENT AND INTERNAL STRUCTURE OF EARLY-TYPE GALAXIES

    NARCIS (Netherlands)

    Treu, Tommaso; Gavazzi, Raphael; Gorecki, Alexia; Marshall, Philip J.; Koopmans, Leon V. E.; Bolton, Adam S.; Moustakas, Leonidas A.; Burles, Scott

    2009-01-01

    We study the relation between the internal structure of early-type galaxies and their environment using 70 strong gravitational lenses from the SLACS Survey. The Sloan Digital Sky Survey (SDSS) database is used to determine two measures of overdensity of galaxies around each lens-the projected numbe

  14. Isophotal shapes of early-type galaxies to very faint levels

    Energy Technology Data Exchange (ETDEWEB)

    Chaware, Laxmikant; Pandey, S. K. [School of Studies in Physics, Pt. Ravishankar Shukla University, Raipur 492010 (India); Cannon, Russell [Australian Astronomical Observatory, P.O. Box 915, North Ryde, NSW 1670 (Australia); Kembhavi, Ajit K. [Inter University Center for Astronomy and Astrophysics, Pune (India); Mahabal, Ashish [California Institute of Technology, Pasadena, CA 91125 (United States)

    2014-06-01

    We report on a study of the isophotal shapes of early-type galaxies to very faint levels, reaching ∼0.1% of the sky brightness. The galaxies are from the Large Format Camera (LFC) fields obtained using the Palomar 5 m Hale Telescope, with integrated exposures ranging from 1 to 4 hr in the Sloan Digital Sky Survey r, i, and z bands. The shapes of isophotes of early-type galaxies are important, as they are correlated with the physical properties of the galaxies and are influenced by galaxy formation processes. In this paper, we report on a sample of 132 E and SO galaxies in one LFC field. We have redshifts for 53 of these, obtained using AAOmega on the Anglo-Australian Telescope. The shapes of early-type galaxies often vary with radius. We derive average values of isophotal shape parameters in four different radial bins along the semi-major axis in each galaxy. We obtain empirical fitting formulae for the probability distribution of the isophotal parameters in each bin and investigate for possible correlations with other global properties of the galaxies. Our main finding is that the isophotal shapes of the inner regions are statistically different from those in the outer regions. This suggests that the outer and inner parts of early-type galaxies have evolved somewhat independently.

  15. Early Family System Types Predict Children's Emotional Attention Biases at School Age

    Science.gov (United States)

    Lindblom, Jallu; Peltola, Mikko J.; Vänskä, Mervi; Hietanen, Jari K.; Laakso, Anu; Tiitinen, Aila; Tulppala, Maija; Punamäki, Raija-Leena

    2017-01-01

    The family environment shapes children's social information processing and emotion regulation. Yet, the long-term effects of early family systems have rarely been studied. This study investigated how family system types predict children's attentional biases toward facial expressions at the age of 10 years. The participants were 79 children from…

  16. Scaling relations in early-type galaxies from integral-field stellar kinematics

    NARCIS (Netherlands)

    Cappellari, M.; Scott, N.; Alatalo, K.; Blitz, L.; Bois, M.; Bournaud, F.; Bureau, M.; Davies, R. L.; Davis, T. A.; de Zeeuw, P. T.; Emsellem, E.; Falcon-Barroso, J.; Khochfar, S.; Krajnovic, D.; Kuntschner, H.; Lablanche, P. -Y; McDermid, R. M.; Morganti, R.; Naab, T.; Sarzi, M.; Serra, P.; van den Bosch, R.C.E.; van de Ven, G.; Weijmans, A.; Young, L. M.

    2010-01-01

    Early-type galaxies (ETGs) satisfy a now classic scaling relation Re ∝ σ1.2eI‑0.8e, the Fundamental Plane (FP; Djorgovski & Davis 1987; Dressler et al. 1987), between their size, stellar velocity dispersion and mean surface brightness. A significant effort has been devoted in the past twenty years t

  17. THE SLACS SURVEY. VIII. THE RELATION BETWEEN ENVIRONMENT AND INTERNAL STRUCTURE OF EARLY-TYPE GALAXIES

    NARCIS (Netherlands)

    Treu, Tommaso; Gavazzi, Raphael; Gorecki, Alexia; Marshall, Philip J.; Koopmans, Leon V. E.; Bolton, Adam S.; Moustakas, Leonidas A.; Burles, Scott

    2009-01-01

    We study the relation between the internal structure of early-type galaxies and their environment using 70 strong gravitational lenses from the SLACS Survey. The Sloan Digital Sky Survey (SDSS) database is used to determine two measures of overdensity of galaxies around each lens-the projected numbe

  18. Formation and evolution of dwarf early-type galaxies in the Virgo cluster I. Internal kinematics

    NARCIS (Netherlands)

    Toloba, E.; Boselli, A.; Cenarro, A. J.; Peletier, R. F.; Gorgas, J.; Gil de Paz, A.; Munoz-Mateos, J. C.

    We present new medium resolution kinematic data for a sample of 21 dwarf early-type galaxies (dEs) mainly in the Virgo cluster, obtained with the WHT and INT telescopes at the Roque de los Muchachos Observatory (La Palma, Spain). These data are used to study the origin of the dwarf elliptical galaxy

  19. Formation and evolution of dwarf early-type galaxies in the Virgo cluster I. Internal kinematics

    NARCIS (Netherlands)

    Toloba, E.; Boselli, A.; Cenarro, A. J.; Peletier, R. F.; Gorgas, J.; Gil de Paz, A.; Munoz-Mateos, J. C.

    2011-01-01

    We present new medium resolution kinematic data for a sample of 21 dwarf early-type galaxies (dEs) mainly in the Virgo cluster, obtained with the WHT and INT telescopes at the Roque de los Muchachos Observatory (La Palma, Spain). These data are used to study the origin of the dwarf elliptical galaxy

  20. The Origin of Dwarf Early-Type Galaxies in the Virgo Cluster

    NARCIS (Netherlands)

    Toloba, E.; Boselli, A.; Peletier, R. F.; Gorgas, J.

    2011-01-01

    We present new medium resolution kinematic data for a sample of 21 dwarf early-type galaxies (dEs) mainly in the Virgo cluster. These data are used to study the origin of the dE population inhabiting rich clusters. Within them we detect two different subpopulations: half of the sample (52%) are rota

  1. Early Family System Types Predict Children's Emotional Attention Biases at School Age

    Science.gov (United States)

    Lindblom, Jallu; Peltola, Mikko J.; Vänskä, Mervi; Hietanen, Jari K.; Laakso, Anu; Tiitinen, Aila; Tulppala, Maija; Punamäki, Raija-Leena

    2017-01-01

    The family environment shapes children's social information processing and emotion regulation. Yet, the long-term effects of early family systems have rarely been studied. This study investigated how family system types predict children's attentional biases toward facial expressions at the age of 10 years. The participants were 79 children from…

  2. Star formation in nearby early-type galaxies: the radio continuum perspective

    NARCIS (Netherlands)

    Nyland, Kristina; Young, Lisa M.; Wrobel, Joan M.; Davis, Timothy A.; Bureau, Martin; Alatalo, Katherine; Morganti, Raffaella; Duc, Pierre-Alain; de Zeeuw, P. T.; McDermid, Richard M.; Crocker, Alison F.; Oosterloo, Tom

    2017-01-01

    We present a 1.4 GHz Karl G. Jansky Very Large Array (VLA) study of a sample of early-type galaxies (ETGs) from the ATLAS3D survey. The radio morphologies of these ETGs at a resolution of θFWHM ≈ 5 arcsec include sources that are compact on sub-kpc scales, resolved structures similar to those seen i

  3. The effect of color type on early wound healing in farmed mink (Neovison vison)

    DEFF Research Database (Denmark)

    Jespersen, A.; Jensen, H. E.; Agger, J. F.

    2017-01-01

    Background: Individual differences of mink, including color type, are speculated to affect the course of wound healing, thereby impacting wound assessment and management on the farms, as well as the assessment of wounds in forensic cases. In this study, we examined the effect of color type on early...... wound healing in farmed mink. Full thickness excisional wounds (2 x 2 cm) were made on the back in 18 mink of the color types Brown, Silverblue and Blue Iris. Gross and microscopic pathology of the wounds was evaluated 2 days post-wounding together with degree of wound size reduction, presence...

  4. Glucosylsphingosine accumulation in mice and patients with type 2 Gaucher disease begins early in gestation.

    Science.gov (United States)

    Orvisky, E; Sidransky, E; McKinney, C E; Lamarca, M E; Samimi, R; Krasnewich, D; Martin, B M; Ginns, E I

    2000-08-01

    Gaucher disease, the most common of the sphingolipidoses, results from the inherited deficiency of the enzyme glucocerebrosidase (EC 3.2.1.45). Although type 2 (acute neuronopathic) Gaucher disease is associated with rapidly progressive and fatal neurologic deterioration, the pathophysiologic mechanisms leading to the neurologic symptoms and early demise remain uncharacterized. While the pathology encountered in Gaucher disease has been attributed to glucocerebroside storage, glucosylsphingosine (Glc-sph), a cytotoxic compound, also accumulates in the tissues. Elevations of brain Glc-sph have been reported in patients with types 2 and 3 Gaucher disease. In this study, Glc-sph levels were measured using HPLC in tissues from mice with type 2 Gaucher disease created with a null glucocerebrosidase allele. Compared with unaffected littermates, homozygous mice with type 2 Gaucher disease had approximately a 100-fold elevation of Glc-sph in brain, as well as elevated levels in other tissues. This accumulation was detected in utero by E 13 and increased progressively throughout gestation. Similarly, elevated Glc-sph levels were seen in human fetuses with type 2 Gaucher disease, indicating that therapy initiated after birth may be too late to prevent the sequelae of progressive neurologic damage that begins early in gestation. These findings suggest that the accumulation of Glc-sph may be responsible for the rapid demise of mice with type 2 Gaucher disease and the devastating clinical course seen in patients with type 2 Gaucher disease.

  5. Influence of muscle fiber type composition on early fat accumulation under high-fat diet challenge.

    Science.gov (United States)

    Hua, Ning; Takahashi, Hirokazu; Yee, Grace M; Kitajima, Yoichiro; Katagiri, Sayaka; Kojima, Motoyasu; Anzai, Keizo; Eguchi, Yuichiro; Hamilton, James A

    2017-01-01

    To investigate whether differences in muscle fiber types affect early-stage fat accumulation, under high fat diet challenge in mice. Twelve healthy male C57BL/6 mice experienced with short-term (6 weeks) diet treatment for the evaluation of early pattern changes in muscular fat. The mice were randomly divided into two groups: high fat diet (n = 8) and normal control diet (n = 4). Extra- and intra-myocellular lipid (EMCL and IMCL) in lumbar muscles (type I fiber predominant) and tibialis anterior (TA) muscle (type II fiber predominant) were determined using magnetic resonance spectroscopy (MRS). Correlation of EMCL, IMCL and their ratio between TA and lumbar muscles was evaluated. EMCL increased greatly in both muscle types after high fat diet. IMCL in TA and lumbar muscles increased to a much lower extent, with a slightly greater increase in TA muscles. EMCLs in the 2 muscles were positively correlated (r = 0.84, p = 0.01), but IMCLs showed a negative relationship (r = -0.84, p = 0.01). In lumbar muscles, high fat diet significantly decreased type I fiber while it increased type II fiber (all p≤0.001). In TA muscle, there was no significant fiber type shifting (p>0.05). Under short-time high fat diet challenge, lipid tends to initially accumulate extra-cellularly. In addition, compared to type II dominant muscle, Type I dominant muscle was less susceptible to IMCL accumulation but more to fiber type shifting. These phenomena might reflect compensative responses of skeletal muscle to dietary lipid overload in order to regulate metabolic homeostasis.

  6. Gas-Bearing Early-Type Dwarf Galaxies in Virgo: Evidence for Recent Accretion

    CERN Document Server

    Hallenbeck, Gregory; Huang, Shan; Haynes, Martha P; Giovanelli, Riccardo; Boselli, Alessandro; Boissier, Samuel; Heinis, Sebastien; Cortese, Luca; Fabello, Silvia

    2012-01-01

    We investigate the dwarf (M_B> -16) galaxies in the Virgo cluster in the radio, optical, and ultraviolet regimes. Of the 365 galaxies in this sample, 80 have been detected in HI by the Arecibo Legacy Fast ALFA survey. These detections include 12 early-type dwarfs which have HI and stellar masses similar to the cluster dwarf irregulars and BCDs. In this sample of 12, half have star-formation properties similar to late type dwarfs, while the other half are quiescent like typical early-type dwarfs. We also discuss three possible mechanisms for their evolution: that they are infalling field galaxies that have been or are currently being evolved by the cluster, that they are stripped objects whose gas is recycled, and that the observed HI has been recently reaccreted. Evolution by the cluster adequately explains the star-forming half of the sample, but the quiescent class of early-type dwarfs is most consistent with having recently reaccreted their gas.

  7. The TESIS Project: Revealing Massive Early-Type Galaxies at z > 1

    Science.gov (United States)

    Saracco, P.; Longhetti, M.; Severgnini, P.; Della Ceca, R.; Braito, V.; Bender, R.; Drory, N.; Feulner, G.; Hopp, U.; Mannucci, F.; Maraston, C.

    How and when present-day massive early-type galaxies built up and what type of evolution has characterized their growth (star formation and/or merging) still remain open issues. The different competing scenarios of galaxy formation predict much different properties of early-type galaxies at z > 1. The "monolithic" collapse predicts that massive spheroids formed at high redshift (z > 2.5-3) and that their comoving density is constant at z 1, their comoving density decreases from z = 0 to z ~ 1.5 and they should experience their last burst of star formation at z 1 can be probed observationally once a well defined sample of massive early-types at z > 1 is available. We are constructing such a sample through a dedicated near-IR very low resolution (λ/Δλ≃50) spectroscopic survey (TNG EROs Spectroscopic Identification Survey, TESIS, [6]) of a complete sample of 30 bright (K < 18.5) Extremely Red Objects (EROs).

  8. The chemical abundance analysis of normal early A- and late B-type stars

    CERN Document Server

    Fossati, L; Bagnulo, S; Alecian, E; Grunhut, J; Kochukhov, O; Wade, G

    2009-01-01

    Modern spectroscopy of early-type stars often aims at studying complex physical phenomena. Comparatively less attention is paid to identifying and studying the "normal" A- and B-type stars and testing how the basic atomic parameters and standard spectral analysis allow one to fit the observations. We wish to stablish whether the chemical composition of the solar photosphere can be regarded as a reference for early A- and late B-type stars. We have obtained optical high-resolution, high signal-to-noise ratio spectra of three slowly rotating early-type stars (HD 145788, 21 Peg and pi Cet) that show no obvious sign of chemical peculiarity, and performed a very accurate LTE abundance analysis of up to 38 ions of 26 elements (for 21 Peg), using a vast amount of spectral lines visible in the spectral region covered by our spectra. We provide an exhaustive description of the abundance characteristics of the three analysed stars with a critical review of the line parameters used to derive the abundances. We compiled ...

  9. Globular Cluster Populations: First Results from S$^4$G Early-Type Galaxies

    CERN Document Server

    Zaritsky, Dennis; Athanassoula, E; Bosma, Albert; Comerón, Sébastien; Elmegreen, Bruce G; Erroz-Ferrer, Santiago; Gadotti, Dimitri A; Hinz, Joannah L; Ho, Luis C; Holwerda, Benne; Knapen, Johan H; Laine, Jarkko; Laurikainen, Eija; Muñoz-Mateos, Juan Carlos; Salo, Heikki; Sheth, Kartik

    2014-01-01

    Using 3.6$\\mu$m images of 97 early-type galaxies, we develop and verify methodology to measure globular cluster populations from the S$^4$G survey images. We find that 1) the ratio, T$_{\\rm N}$, of the number of clusters, N$_{\\rm CL}$, to parent galaxy stellar mass, M$_*$, rises weakly with M$_*$ for early-type galaxies with M$_* > 10^{10}$ M$_\\odot$ when we calculate galaxy masses using a universal stellar initial mass function (IMF), but that the dependence of T$_{\\rm N}$ on M$_*$ is removed entirely once we correct for the recently uncovered systematic variation of IMF with M$_*$, and 2) for M$_* 10^{10}$ M$_\\odot$ and can be as large as $\\sim 0.02$ for less massive galaxies. These are the first results from the S$^4$G sample of galaxies, and will be enhanced by the sample of early-type galaxies now being added to S$^4$G and complemented by the study of later type galaxies within S$^4$G.

  10. Galaxy populations in the Antlia cluster - III. Properties of faint early-type galaxies

    CERN Document Server

    Castelli, Analia V Smith; Faifer, Favio R; Bassino, Lilia P; Richtler, Tom; Romero, Gisela A; Calderon, Juan Pablo; Caso, Juan Pablo

    2011-01-01

    (Abridge) We present a new analysis of the early-type galaxy population in the central region of the Antlia cluster, focusing on the faint systems like dwarf ellipticals (dE) and dwarf spheroidals (dSph). We confirm 22 early-type galaxies as Antlia members, using GEMINI-GMOS and MAGELLAN-MIKE spectra. Among them, 2 belong to the rare type of compact ellipticals (cE), and 5 are new faint dwarfs that had never been catalogued before. In addition, we present 16 newly identified low surface brightness galaxy candidates, almost half of them displaying morphologies consistent with being Antlia's counterparts of Local Group dSphs, that extend the faint luminosity limit of our study down to MB = -10.1 (BT = 22.6) mag. We built an improved CMR in the Washington photometric system, i.e. integrated T1 magnitudes versus (C - T1) colours, which extends \\sim 4 mag faintwards the limit of spectroscopically confirmed Antlia members. When only confirmed early-type members are considered, this relation extends over 10 mag in l...

  11. The inner structure of early-type galaxies in the Illustris simulation

    CERN Document Server

    Xu, Dandan; Sluse, Dominique; Schneider, Peter; Sonnenfeld, Alessandro; Nelson, Dylan; Vogelsberger, Mark; Hernquist, Lars

    2016-01-01

    Early-type galaxies provide unique tests for the predictions of the cold dark matter cosmology and the baryonic physics assumptions entering models for galaxy formation. In this work, we use the Illustris simulation to study correlations of three main properties of early-type galaxies, namely, the stellar orbital anisotropies, the central dark matter fractions and the central radial density slopes, as well as their redshift evolution since $z=1.0$. We find that lower-mass galaxies or galaxies at higher redshift tend to be bluer in rest-frame colour, have higher central gas fractions, and feature more tangentially anisotropic orbits and steeper central density slopes than their higher-mass or lower-redshift counterparts, respectively. The projected central dark matter fraction within the effective radius shows no significant mass dependence but positively correlates with galaxy effective radii due to the aperture effect. The central density slopes obtained in the simulation by combining strong lensing measurem...

  12. The Evolution of Field Early-Type Galaxies in the FDF and WHDF

    CERN Document Server

    Fritz, Alexander; Ziegler, Bodo L

    2009-01-01

    We explore the properties of 24 field early-type galaxies at 0.20=-0.74\\pm0.08. The M/L evolution of these field galaxies suggests a continuous mass assembly of field early-type galaxies during the last 5 Gyr, that gets support by recent studies of field galaxies up to z~1. Independent evidence for recent SF activity is provided by spectroscopic (OII em., Hdelta) and photometric (rest-frame colors) diagnostics. Based on the Hdelta absorption feature we detect a weak residual SF for galaxies that acco unts for 5%-10% in the total stellar mass of these galaxies. The co-evolution in the luminosity and mass of our galaxies favours a downsizing formation process. We find some evidence that our galaxies experienced a period of SF quenching, possible triggered by AGN activity that is in good agreement with recent results on both observational and theoretical side. (abridged)

  13. Dark-Matter Content of Early-Type Galaxies with Planetary Nebulae

    CERN Document Server

    Napolitano, N R; Coccato, L; Capaccioli, M; Douglas, N G; Noordermeer, E; Merrifield, M R; Kuijken, K; Arnaboldi, M; Gerhard, O; Freeman, K C; De Lorenzi, F; Das, P

    2007-01-01

    We examine the dark matter properties of nearby early-type galaxies using planetary nebulae (PNe) as mass probes. We have designed a specialised instrument, the Planetary Nebula Spectrograph (PN.S) operating at the William Herschel telescope, with the purpose of measuring PN velocities with best efficiency. The primary scientific objective of this custom-built instrument is the study of the PN kinematics in 12 ordinary round galaxies. Preliminary results showing a dearth of dark matter in ordinary galaxies (Romanowsky et al. 2003) are now confirmed by the first complete PN.S datasets. On the other hand early-type galaxies with a "regular" dark matter content are starting to be observed among the brighter PN.S target sample, thus confirming a correlation between the global dark-to-luminous mass virial ratio (f_DM=M_DM/M_star) and the galaxy luminosity and mass.

  14. Dynamics of early embryo development in reference to endosperm and embryo types in angiosperms

    Directory of Open Access Journals (Sweden)

    Olga Erdelska

    2014-01-01

    Full Text Available The mitotic cycle of the endosperm cells is relatively short in the firsit phases of the postfertilization development. The endosperm type does not significantly influence the duration of the mitotic cycle; it might, however, influence the dynamics of zygote and embryo development. The quick development and early end of cellular endosperm proliferation is connected with the fact that it is, in most cases, bound to small, "spare" or "saving" tenuinucellate and unitegmic ovules. Structural differences in the behaviour of the endosperm of different types, in the phase of globular and early heart embryo, might point to differences in the time or way of transition of the embryo from suspensorial to surface nutrition.

  15. Tidally Compressed Gas in Centers of Early Type and Ultraluminous Galaxies

    CERN Document Server

    Das, M; Das, Mousumi; Jog, Chanda J.

    1999-01-01

    In this paper we propose that the compressive tidal field in the centers of flat-core early type galaxies and ultraluminous galaxies compresses molecular clouds producing dense gas obseved in the centers of these galaxies. The effect of galactic tidal fields is usually considered disruptive in the literature. However, for some galaxies, the mass profile flattens towards the center and the resulting galactic tidal field is not disruptive but instead it is compressive within the flat-core region. We have used the virial theorem to determine the minimum density of a molecular cloud to be stable and gravitationally bound within the tidally compressive region of a galaxy. We have applied the mechanism to determine the mean molecular cloud densities in the centers of a sample of flat-core, early-type galaxies and ultraluminous galaxies.

  16. Early-type galaxies with neutral hydrogen in the Virgo cluster from the ALFALFA survey

    CERN Document Server

    Alighieri, S di Serego; Giovanardi, C; Pellegrini, S; Trinchieri, G

    2008-01-01

    We extend our published work on the neutral hydrogen content of early-type galaxies in the Virgo cluster using the catalogue of detected sources from the ALFALFA survey, by showing the 21cm spectra of all the detected galaxies and discussing a deeper analysis of the ALFALFA datacubes, searching for lower S/N sources. A view of the multiphase interstellar medium of M86 is also presented, by comparing images of the cold, warm and hot phases.

  17. Circumstellar dust, PAHs and stellar populations in early-type galaxies: insights from GALEX and WISE

    Science.gov (United States)

    Simonian, Gregory V.; Martini, Paul

    2017-02-01

    A majority of early-type galaxies contain interstellar dust, yet the origin of this dust, and why the dust sometimes exhibits unusual polycyclic aromatic hydrocarbon (PAH) ratios, remains a mystery. If the dust is internally produced, it likely originates from the large number of asymptotic giant branch stars associated with the old stellar population. We present GALEX and WISE elliptical aperture photometry of ˜310 early-type galaxies with Spitzer mid-infrared spectroscopy and/or ancillary data from ATLAS3D, to characterize their circumstellar dust and the shape of the radiation field that illuminates the interstellar PAHs. We find that circumstellar dust is ubiquitous in early-type galaxies, which indicates some tension between stellar population age estimates and models for circumstellar dust production in very old stellar populations. We also use dynamical masses from ATLAS3D to show that WISE W1 (3.4 μm) mass-to-light ratios are consistent with the initial mass function variation found by previous work. While the stellar population differences in early-type galaxies correspond to a range of radiation field shapes incident upon the diffuse dust, the ratio of the ionization-sensitive 7.7 μm/11.3 μm PAH feature does not correlate with the shape of the radiation field, nor to variations with the size-sensitive 11.3 μm/17 μm ratio. The 7.7 μm/11.3 μm PAH ratio does tend to be smaller in galaxies with proportionally greater H2 emission, which is evidence that processing of primarily smaller grains by shocks is responsible for the unusual ratios, rather than substantial differences in the overall PAH size or ionization distribution.

  18. Large-Scale Outer Rings of Early-type Disk Galaxies

    CERN Document Server

    Kostiuk, Irina P

    2015-01-01

    We have searched for presence of current star formation in outer stellar rings of early-type disk (S0-Sb) galaxies by inspecting a representative sample of nearby galaxies with rings from the recent Spitzer catalog ARRAKIS (Comeron et al. 2014). We have found that regular rings (of R-type) reveal young stellar population with the age of less than 200~Myr in about half of all the cases, while in the pseudorings (open rings, R'), which inhabit only spiral galaxies, current star formation proceeds almost always.

  19. Mass-to-light ratios in early-type galaxies and the dark matter content

    CERN Document Server

    Capaccioli, M; Arnaboldi, M

    2002-01-01

    The distribution of the radial trends of the mass-to-light ratios (M/L) within an assorted sample of early-type galaxies is discussed. Three classes of galaxies are identified according to their M/L gradients. Two such classes are characterized by the presence or by the absence of a radial gradient of the dark-matter (DM) distribution. A third class contains objects which are likely undergoing interaction; they exhibit steep M/L gradients which are possibly the result of a wrong assumption on their equilibrium conditions. Finally, a possible correlation between DM content and morphological types is briefly discussed.

  20. Star formation in early-type galaxies: the role of stellar winds and kinematics

    CERN Document Server

    Pellegrini, S; Ciotti, L

    2015-01-01

    Early-type galaxies (ETGs) host a hot ISM produced mainly by stellar winds, and heated by Type Ia supernovae and the thermalization of stellar motions. High resolution 2D hydrodynamical simulations showed that ordered rotation in the stellar component results in the formation of a centrifugally supported cold equatorial disc. In a recent numerical investigation we found that subsequent generations of stars are formed in this cold disc; this process consumes most of the cold gas, leaving at the present epoch cold masses comparable to those observed. Most of the new stellar mass formed a few Gyrs ago, and resides in a disc.

  1. Intrinsic Axis Ratio Distribution of Early-type Galaxies From Sloan Digital Sky Survey

    CERN Document Server

    Kimm, Taysun

    2007-01-01

    Using Sloan Digital Sky Survey Data Release 5, we have investigated the intrinsic axis ratio distribution (ARD) for early-type galaxies. We have constructed a volume-limited sample of 3,922 visually-inspected early-type galaxies at $0.05 \\leq z \\leq 0.06$ carefully considering sampling biases caused by the galaxy isophotal size and luminosity. We attempt to de-project the observed ARD into three-dimensional types (oblate, prolate, and triaxial), which are classified in terms of triaxiality. We confirm that no linear combination of $randomly$-distributed axis ratios of the three types can reproduce the observed ARD. However, using Gaussian intrinsic distributions, we have found reasonable fits to the data with preferred mean axis ratios for oblate, prolate, and triaxial (triaxials in two axis ratios), $\\mu_o=0.44, \\mu_p=0.72, \\mu_{t,\\beta}=0.92, \\mu_{t,\\gamma}=0.78$ where the fractions of oblate, prolate and triaxial types are \\textrm{O:P:T}=0.29^{\\pm0.09}:0.26^{\\pm0.11}:0.45^{\\pm0.13}$. We have also found tha...

  2. [Early rehabilitation program in uncomplicated Stanford type B acute aortic dissection].

    Science.gov (United States)

    Inoue, Takehiko; Ichihara, Tetsuya; Sakaguchi, Hidehito; Kanamori, Taro

    2014-08-01

    Between December 2009 and August 2011, 120 patients with uncomplicated Stanford type B acute aortic dissection( UBAD) received medical treatment. In October 2010, we initiated an early rehabilitation program for UBAD patients in an acute phase. This early rehabilitation program, which was aimed at enabling the patient to walk around the ward within 2 days, was conducted for 87 consecutive patients;the remaining 33 were subjected to the conventional rehabilitation program. Mortality was not significantly different between the 2 groups. The incidence of atelectasis, need for mechanical ventilation, and intensive care unit syndrome during medical treatment occurred in 48% (16/33), 15% ( 5/33), and 30% ( 10/33), respectively, of the conventional group and in 3.4% ( 3/87), 1.1% (1/87), and 3.4% ( 3/87), respectively, of the early rehabilitation group. The outer diameter of the aorta was dilated after 4 weeks' rehabilitation in smaller percentage of patients in the early rehabilitation group than the conventional one. Thus, the early rehabilitation program was more effective for patients with UBAD than the conventional one.

  3. The Optical and Near-Infrared Morphologies of Isolated Early Type Galaxies

    CERN Document Server

    Colbert, J W; Zabludoff, A I; Colbert, James W.; Mulchaey, John S.; Zabludoff, Ann I.

    2001-01-01

    In order to study early type galaxies in their simplest environments, we have constructed a well-defined sample of 30 isolated galaxies. The sample contains all RC3 early-type galaxies with no other cataloged galaxy with known redshift lying within a projected radius of 1 (h_100)^{-1} Mpc and =/- 1000 km/s (where we use the recessional velocities in the RC3). We have obtained optical and near-infrared images of 23 of the galaxies and of a comparison sample of 13 early-type galaxies in X-ray detected poor groups of galaxies. We have applied the techniques of unsharp masking, galaxy model division, and color maps to search for morphological features that might provide clues to the evolution of these galaxies. Evidence for dust features is found in approximately 75% of both the isolated and group galaxies (17 of 22 and 9 of 12, respectively). However, shells or tidal features are much more prevalent in our isolated sample than in our group sample (9 of 22 or 41% versus 1 of 12 or 8%, respectively). The isolation...

  4. Circumstellar Dust, PAHs, and Stellar Populations in Early-Type Galaxies: Insights from GALEX and WISE

    CERN Document Server

    Simonian, Gregory V

    2016-01-01

    A majority of early-type galaxies contain interstellar dust, yet the origin of this dust, and why the dust sometimes exhibits unusual PAH ratios, remains a mystery. If the dust is internally produced, the most likely origin is the large number of AGB stars associated with the old stellar population. We present GALEX and WISE elliptical aperture photometry of $\\sim350$ early-type galaxies with Spitzer mid-infrared spectroscopy and/or ancillary data from ATLAS3D, to characterize their circumstellar dust and the shape of the radiation field that illuminates the interstellar PAHs. We find that circumstellar dust is ubiquitous in early-type galaxies, which indicates some tension between stellar population age estimates and models for circumstellar dust production in very old stellar populations. We also use dynamical masses from ATLAS3D to show that WISE W1 (3.4 $\\mu$m) mass-to-light ratios are inconsistent with model predictions for a single IMF, as found by previous work. While the stellar population differences...

  5. Recent Structural Evolution of Early-Type Galaxies: Size Growth from z=1 to z=0

    CERN Document Server

    van der Wel, Arjen; Zirm, Andrew W; Franx, Marijn; Rettura, Alessandro; Illingworth, Garth D; Ford, Holland C

    2008-01-01

    Strong size and internal density evolution of early-type galaxies between z~2 and the present has been reported by several authors. Here we analyze samples of nearby and distant (z~1) galaxies with dynamically measured masses in order to confirm the previous, model-dependent results and constrain the uncertainties that may play a role. Velocity dispersion measurements are taken from the literature for 50 morphologically selected 0.8early-type galaxies with typical masses 2e11 Msol. Sizes are determined with ACS imaging. We compare the distant sample with a large sample of nearby (0.04early-type galaxies extracted from the SDSSfor which we determine sizes, masses, and densities in a consistent manner, using simulations to quantify systematic differences between the size measurements of nearby and distant galaxies. We find a highly significant structural difference between the nearby and distant samples, regardless of sample selection effects. The implied evolution ...

  6. Molecular Gas and Star Formation in Local Early-Type Galaxies

    CERN Document Server

    Bureau, M; Alatalo, K; Crocker, A F; Blitz, L; Young, L M; Combes, F; Bois, M; Bournaud, F; Cappellari, M; Davies, R L; de Zeeuw, P T; Duc, P -A; Emsellem, E; Khochfar, S; Krajnovic, D; Kuntschner, H; Lablanche, P -Y; McDermid, R M; Morganti, R; Naab, T; Oosterloo, T; Sarzi, M; Scott, N; Serra, P; Weijmans, A

    2011-01-01

    The molecular gas content of local early-type galaxies is constrained and discussed in relation to their evolution. First, as part of the Atlas3D survey, we present the first complete, large (260 objects), volume-limited single-dish survey of CO in normal local early-type galaxies. We find a surprisingly high detection rate of 22%, independent of luminosity and at best weakly dependent on environment. Second, the extent of the molecular gas is constrained with CO synthesis imaging, and a variety of morphologies is revealed. The kinematics of the molecular gas and stars are often misaligned, implying an external gas origin in over a third of the systems, although this behaviour is drastically diffferent between field and cluster environments. Third, many objects appear to be in the process of forming regular kpc-size decoupled disks, and a star formation sequence can be sketched by piecing together multi-wavelength information on the molecular gas, current star formation, and young stars. Last, early-type gala...

  7. The inner structure of early-type galaxies in the Illustris simulation

    Science.gov (United States)

    Xu, Dandan; Springel, Volker; Sluse, Dominique; Schneider, Peter; Sonnenfeld, Alessandro; Nelson, Dylan; Vogelsberger, Mark; Hernquist, Lars

    2017-08-01

    Early-type galaxies provide unique tests for the predictions of the cold dark matter cosmology and the baryonic physics assumptions entering models for galaxy formation. In this work, we use the Illustris simulation to study correlations of three main properties of early-type galaxies, namely the stellar orbital anisotropies, the central dark matter fractions and the central radial density slopes, as well as their redshift evolution since z = 1.0. We find that lower mass galaxies or galaxies at higher redshift tend to be bluer in rest-frame colour, have higher central gas fractions, and feature more tangentially anisotropic orbits and steeper central density slopes than their higher mass or lower redshift counterparts, respectively. The projected central dark matter fraction within the effective radius shows a very mild mass dependence but positively correlates with galaxy effective radii due to the aperture effect. The central density slopes obtained by combining strong lensing measurements with single-aperture kinematics are found to differ from the true density slopes. We identify systematic biases in this measurement to be due to two common modelling assumptions, isotropic stellar orbital distributions and power-law density profiles. We also compare the properties of early-type galaxies in Illustris to those from existing galaxy and strong lensing surveys; we find in general broad agreement but also some tension, which poses a potential challenge to the stellar formation and feedback models adopted by the simulation.

  8. AMUSE-Field II. Nucleation of early-type galaxies in the field vs. cluster environment

    CERN Document Server

    Baldassare, Vivienne F; Miller, Brendan P; Plotkin, Richard M; Treu, Tommaso; Valluri, Monica; Woo, Jong-Hak

    2014-01-01

    The optical light profiles of nearby early type galaxies are known to exhibit a smooth transition from nuclear light deficits to nuclear light excesses with decreasing galaxy mass, with as much as 80 per cent of the galaxies with stellar masses below 10^10 Msun hosting a massive nuclear star cluster. At the same time, while all massive galaxies are thought to harbor nuclear super-massive black holes (SMBHs), observational evidence for SMBHs is slim at the low end of the mass function. Here, we explore the environmental dependence of the nucleation fraction by comparing two homogeneous samples of nearby field vs. cluster early type galaxies with uniform Hubble Space Telescope (HST) coverage. Existing Chandra X-ray Telescope data for both samples yield complementary information on low-level accretion onto nuclear SMBHs. Specifically, we report on dual-band (F475W & F850LP) Advanced Camera for Surveys (ACS) imaging data for 28 out of the 103 field early type galaxies that compose the AMUSE-Field Chandra surv...

  9. Not Dead Yet: Cool Circumgalactic Gas in the Halos of Early Type Galaxies

    CERN Document Server

    Thom, Christopher; Werk, Jessica K; Prochaska, J Xavier; Oppenheimer, Benjamin D; Peeples, Molly S; Tripp, Todd M; Katz, Neal S; O'Meara, John M; Ford, Amanda Brady; Dave, Romeel; Sembach, Kenneth R; Weinberg, David H

    2012-01-01

    We report new observations of circumgalactic gas in the halos of early type galaxies obtained by the COS-Halos Survey with the Cosmic Origins Spectrograph onboard the Hubble Space Telescope. We find that detections of HI surrounding early type galaxies are typically as common and strong as around star-forming galaxies, implying that the total mass of circumgalactic material is comparable in the two populations. For early type galaxies, the covering fraction for HI absorption above 10^16 cm^2 is ~40-50% within ~150 kpc. Line widths and kinematics of the detected material show it to be cold (T ~< 10^5 K) in comparison to the virial temperature of the host halos. The implied masses of cool, photoionized CGM baryons may be up to 10^9 --- 10^11 Msun. Contrary to some theoretical expectations, strong halo HI absorbers do not disappear as part of the quenching of star-formation. Even passive galaxies retain significant reservoirs of halo baryons which could replenish the interstellar gas reservoir and eventually ...

  10. VizieR Online Data Catalog: Nearby early-type galaxies catalog (Dabringhausen+, 2016)

    Science.gov (United States)

    Dabringhausen, J.; Fellhauer, M.

    2016-06-01

    We present a catalogue of 1715 early-type galaxies from the literature, spanning the luminosity range from faint dwarf spheroidal galaxies to giant elliptical galaxies. The aim of this catalogue is to be one of the most comprehensive and publicly available collections of data on early-type galaxies. The emphasis in this catalogue lies on dwarf elliptical galaxies, for which some samples with detailed data have been published recently. For almost all of the early-type galaxies included in it, this catalogue contains data on their locations, distances, redshifts, half-light radii, the masses of their stellar populations and apparent magnitudes in various passbands. Data on metallicity and various colours are available for a majority of the galaxies presented here. The data on magnitudes, colours, metallicities and masses of the stellar populations is supplemented with entries that are based on fits to data from simple stellar population models and existing data from observations. Also, some simple transformations have been applied to the data on magnitudes, colours and metallicities in this catalog, in order to increase the homogeneity of this data. Estimates on the Sersic profiles, internal velocity dispersions, maximum rotational velocities, dynamical masses and ages are listed for several hundreds of the galaxies in this catalogue. Finally, each quantity listed in this catalogue is accompanied with information on its source, so that users of this catalogue can easily exclude data that they do not consider as reliable enough for their purposes. (10 data files).

  11. The Sensitivity of Harassment to Orbit: Mass Loss from Early-Type Dwarfs in Galaxy Clusters

    CERN Document Server

    Smith, Rory; Beasley, Michael A; Candlish, Graeme N; Gibson, Brad K; Puzia, Thomas H; Janz, Joachim; Knebe, Alexander; Aguerri, J Alfonso L; Lisker, Thorsten; Hensler, Gerhard; Fellhauer, Michael; Ferrarese, Laura; Yi, Sukyoung K

    2015-01-01

    We conduct a comprehensive numerical study of the orbital dependence of harassment on early-type dwarfs consisting of 168 different orbits within a realistic, Virgo-like cluster, varying in eccentricity and pericentre distance. We find harassment is only effective at stripping stars or truncating their stellar disks for orbits that enter deep into the cluster core. Comparing to the orbital distribution in cosmological simulations, we find that the majority of the orbits (more than three quarters) result in no stellar mass loss. We also study the effects on the radial profiles of the globular cluster systems of early-type dwarfs. We find these are significantly altered only if harassment is very strong. This suggests that perhaps most early-type dwarfs in clusters such as Virgo have not suffered any tidal stripping of stars or globular clusters due to harassment, as these components are safely embedded deep within their dark matter halo. We demonstrate that this result is actually consistent with an earlier st...

  12. The stellar populations in the low luminosity, early-type galaxy NGC59

    CERN Document Server

    Sansom, A E; Deakin, M A; Väisänen, P; Kniazev, A Y; van Loon, J Th

    2015-01-01

    Low luminosity galaxies may be the building blocks of more luminous systems. Southern African Large Telescope (SALT) observations of the low luminosity, early-type galaxy NGC59 are obtained and analysed. These data are used to measure the stellar population parameters in the centre and off-centre regions of this galaxy, in order to uncover its likely star formation history. We find evidence of older stars, in addition to young stars in the emission line regions. The metallicity of the stellar population is constrained to be [Z/H] ~ -1.1 to -1.6, which is extremely low, even for this low luminosity galaxy, since it is not classed as a dwarf spheroidal galaxy. The measured [alpha/Fe] ratio is sub-solar, which indicates an extended star formation history in NGC59. If such objects formed the building blocks of more massive, early-type galaxies, then they must have been gaseous mergers, rather than dry mergers, in order to increase the metals to observed levels in luminous, early-type galaxies.

  13. The ATLAS3D project - XXVII. Cold gas and the colours and ages of early-type galaxies

    NARCIS (Netherlands)

    Young, Lisa M.; Scott, Nicholas; Serra, Paolo; Alatalo, Katherine; Bayet, Estelle; Blitz, Leo; Bois, Maxime; Bournaud, Frédéric; Bureau, Martin; Crocker, Alison F.; Cappellari, Michele; Davies, Roger L.; Davis, Timothy A.; de Zeeuw, P. T.; Duc, Pierre-Alain; Emsellem, Eric; Khochfar, Sadegh; Krajnović, Davor; Kuntschner, Harald; McDermid, Richard M.; Morganti, Raffaella; Naab, Thorsten; Oosterloo, Tom; Sarzi, Marc; Weijmans, Anne-Marie

    2014-01-01

    We present a study of the cold gas contents of the ATLAS3D early-type galaxies, in the context of their optical colours, near-ultraviolet colours and Hβ absorption line strengths. Early-type (elliptical and lenticular) galaxies are not as gas poor as previously thought, and at least 40 per cent of

  14. Studies of Virgo cluster early-type dwarf galaxies with the SDSS: I. On the possible disk nature of bright early-type dwarfs

    CERN Document Server

    Lisker, T; Grebel, E K; Binggeli, Bruno; Grebel, Eva K.; Lisker, Thorsten

    2006-01-01

    We present a systematic search for disks in 476 Virgo cluster early-type dwarf (dE) galaxies. Disk features (spiral arms, edge-on disks, or bars) were identified by applying unsharp masks to a combined image from three bands (g, r, i), as well as by subtracting the axisymmetric light distribution of each galaxy from that image. 14 objects are unambiguous identifications of disks, 10 objects show 'probable disk' features, and 17 objects show 'possible disk' features. The number fraction of these galaxies, for which we introduce the term dEdi, reaches more than 50% at the bright end of the dE population, and decreases to less than 5% for magnitudes B>16. The luminosity function of our full dE sample can be explained by a superposition of dEdis and ordinary dEs, strongly suggesting that dEdis are a distinct type of galaxy. This is supported by the projected spatial distribution: dEdis show basically no clustering and roughly follow the spatial distribution of spirals and irregulars, whereas ordinary dEs are dist...

  15. Early Vocabulary in Relation to Gender, Bilingualism, Type, and Duration of Childcare

    Science.gov (United States)

    Stolarova, M.; Brielmann, A. A.; Wolf, C.; Rinker, T.; Burke, T; Baayen, H.

    2016-01-01

    This study investigates the predictive value of child-related and environmental characteristics for early lexical development. The German productive vocabulary of 51 2-year-olds (27 girls), assessed via parental report, was analyzed taking children’s gender, the type of early care they experienced, and their mono- versus bilingual language composition into consideration. The children were from an educationally homogeneous group of families and state-regulated daycare facilities with high structural quality. All investigated subgroups exhibited German vocabulary size within the expected normative range. Gender differences in vocabulary composition, but not in size, were observed. There were no general differences in vocabulary size or composition between the 2 care groups. An interaction between the predictors gender and care arrangement showed that girls without regular daycare experience before the age of 2 years had a somewhat larger vocabulary than all other investigated subgroups of children. The vocabulary size of the 2-year-old children in daycare correlated positively with the duration of their daycare experience prior to testing. The small subgroup of bilingual children investigated exhibited slightly lower but still normative German expressive vocabulary size and a different vocabulary composition compared to the monolingual children. This study expands current knowledge about relevant predictors of early vocabulary. It shows that in the absence of educational disadvantages the duration of early daycare experience of high structural quality is positively associated with vocabulary size but also points to the fact that environmental characteristics, such as type of care, might affect boys’ and girls’ early vocabulary in different ways. PMID:28127412

  16. Abundance analysis of 5 early-type stars in the young open cluster IC2391

    CERN Document Server

    Stuetz, C; Jehin, E; Ledoux, C; Cabanac, R A; Melo, C; Smoker, J V; Stuetz, Ch.

    2006-01-01

    It is unclear whether chemically peculiar stars of the upper main sequence represent a class completely distinct from normal A-type stars, or whether there exists a continuous transition from the normal to the most peculiar late F- to early B-type stars. A systematic abundance analysis of open cluster early-type stars would help to relate the observed differences of the chemical abundances of the photospheres to other stellar characteristics, without being concerned by possible different original chemical composition. Furthermore, if a continuous transition region from the very peculiar to the so called normal A-F stars exists, it should be possible to detect objects with mild peculiarities. As a first step of a larger project, an abundance analysis of 5 F-A type stars in the young cluster IC2391 was performed using high resolution spectra obtained with the UVES instrument of the ESO VLT. Our targets seem to follow a general abundance pattern: close to solar abundance of the light elements and iron peak eleme...

  17. Morphological classification and structural parameters for early-type galaxies in the Coma cluster

    CERN Document Server

    Andreon, S; Michard, R; Nieto, J L; Poulain, P

    1995-01-01

    We present the results of an isophotal shape analysis of three samples of galaxies in the Coma cluster. Quantitative morphology, together with structural and photometric parameters, is given for each galaxy. Special emphasis has been placed on the detailed classification of early-type galaxies. The three samples are: i) a sample of 97 early-type galaxies brighter than m_B = 17.00 falling within one degree from the center of the Coma cluster; these galaxies were observed with CCD cameras, mostly in good to excellent resolution conditions; ii) a magnitude complete sample of 107 galaxies of all morphological types down to m_B = 17.00 falling in a circular region of 50 arcmin diameter, slightly offcentered to the North-West of the cluster center; the images for this and the next sample come from digitized photographic plates; iii) a complete comparison sample of 26 galaxies of all morphological types down to m_R = 16.05 (or m_B \\simeq 17.5), also in a region of 50 arcmin diameter, but centered 2.6 degrees West of...

  18. Proton and Fe Ion-Induced Early and Late Chromosome Aberrations in Different Cell Types

    Science.gov (United States)

    Wu, Honglu; Lu, Tao; Yeshitla, Samrawit; Zhang, Ye; Kadhim, Munira

    2016-01-01

    An early stage of cancer development is believed to be genomic instability (GI) which accelerates the mutation rate in the descendants of the cells surviving radiation exposure. To investigate GI induced by charged particles, we exposed human lymphocytes, human fibroblast cells, and human mammary epithelial cells to high energy protons and Fe ions. In addition, we also investigated GI in bone marrow cells isolated from CBA/CaH (CBA) and C57BL/6 (C57) mice, by analyzing cell survival and chromosome aberrations in the cells after multiple cell divisions. Results analyzed so far from the experiments indicated different sensitivities to charged particles between CBA/CaH (CBA) and C57BL/6 (C57) mouse strains, suggesting that there are two main types of response to irradiation: 1) responses associated with survival of damaged cells and 2) responses associated with the induction of non-clonal chromosomal instability in the surviving progeny of stem cells. Previously, we reported that the RBE for initial chromosome damages was high in human lymphocytes exposed to Fe ions. Our results with different cell types demonstrated different RBE values between different cell types and between early and late chromosomal damages. This study also attempts to offer an explanation for the varying RBE values for different cancer types.

  19. Altered Kv3.3 channel gating in early-onset spinocerebellar ataxia type 13.

    Science.gov (United States)

    Minassian, Natali A; Lin, Meng-Chin A; Papazian, Diane M

    2012-04-01

    Mutations in Kv3.3 cause spinocerebellar ataxia type 13 (SCA13). Depending on the causative mutation, SCA13 is either a neurodevelopmental disorder that is evident in infancy or a progressive neurodegenerative disease that emerges during adulthood. Previous studies did not clarify the relationship between these distinct clinical phenotypes and the effects of SCA13 mutations on Kv3.3 function. The F448L mutation alters channel gating and causes early-onset SCA13. R420H and R423H suppress Kv3 current amplitude by a dominant negative mechanism. However, R420H results in the adult form of the disease whereas R423H produces the early-onset, neurodevelopmental form with significant clinical overlap with F448L. Since individuals with SCA13 have one wild type and one mutant allele of the Kv3.3 gene, we analysed the properties of tetrameric channels formed by mixtures of wild type and mutant subunits. We report that one R420H subunit and at least one R423H subunit can co-assemble with the wild type protein to form active channels. The functional properties of channels containing R420H and wild type subunits strongly resemble those of wild type alone. In contrast, channels containing R423H and wild type subunits show significantly altered gating, including a hyperpolarized shift in the voltage dependence of activation, slower activation, and modestly slower deactivation. Notably, these effects resemble the modified gating seen in channels containing a mixture of F448L and wild type subunits, although the F448L subunit slows deactivation more dramatically than the R423H subunit. Our results suggest that the clinical severity of R423H reflects its dual dominant negative and dominant gain of function effects. However, as shown by R420H, reducing current amplitude without altering gating does not result in infant onset disease. Therefore, our data strongly suggest that changes in Kv3.3 gating contribute significantly to an early age of onset in SCA13.

  20. GLOBULAR CLUSTER POPULATIONS: FIRST RESULTS FROM S{sup 4}G EARLY-TYPE GALAXIES

    Energy Technology Data Exchange (ETDEWEB)

    Zaritsky, Dennis [Steward Observatory, University of Arizona, 933 North Cherry Avenue, Tucson, AZ 85721 (United States); Aravena, Manuel [Núcleo de Astronomía, Facultad de Ingeniería, Universidad Diego Portales, Avenida Ejército 441, Santiago (Chile); Athanassoula, E.; Bosma, Albert [Aix Marseille Université, CNRS, LAM (Laboratoire d' Astrophysique de Marseille) UMR 7326, F-13388 Marseille (France); Comerón, Sébastien; Laine, Jarkko; Laurikainen, Eija; Salo, Heikki [Astronomy Division, Department of Physics, P.O. Box 3000, FI-90014 University of Oulu (Finland); Elmegreen, Bruce G. [IBM T. J. Watson Research Center, 1101 Kitchawan Road, Yorktown Heights, NY 10598 (United States); Erroz-Ferrer, Santiago; Knapen, Johan H. [Instituto de Astrofísica de Canarias, Vía Lácteas, E-38205 La Laguna (Spain); Gadotti, Dimitri A.; Muñoz-Mateos, Juan Carlos [European Southern Observatory, Casilla 19001, Santiago 19 (Chile); Hinz, Joannah L. [MMT Observatory, P.O. Box 210065, Tucson, AZ 85721 (United States); Ho, Luis C. [Kavli Institute for Astronomy and Astrophysics, Peking University, Beijing 100871 (China); Holwerda, Benne [Leiden Observatory, University of Leiden, Niels Bohrweg 4, NL-2333 Leiden (Netherlands); Sheth, Kartik, E-mail: dennis.zaritsky@gmail.com [National Radio Astronomy Observatory/NAASC, 520 Edgemont Road, Charlottesville, VA 22903 (United States)

    2015-02-01

    Using 3.6 μm images of 97 early-type galaxies, we develop and verify methodology to measure globular cluster populations from the S{sup 4}G survey images. We find that (1) the ratio, T {sub N}, of the number of clusters, N {sub CL}, to parent galaxy stellar mass, M {sub *}, rises weakly with M {sub *} for early-type galaxies with M {sub *} > 10{sup 10} M {sub ☉} when we calculate galaxy masses using a universal stellar initial mass function (IMF) but that the dependence of T {sub N} on M {sub *} is removed entirely once we correct for the recently uncovered systematic variation of IMF with M {sub *}; and (2) for M {sub *} < 10{sup 10} M {sub ☉}, there is no trend between N {sub CL} and M {sub *}, the scatter in T {sub N} is significantly larger (approaching two orders of magnitude), and there is evidence to support a previous, independent suggestion of two families of galaxies. The behavior of N {sub CL} in the lower-mass systems is more difficult to measure because these systems are inherently cluster-poor, but our results may add to previous evidence that large variations in cluster formation and destruction efficiencies are to be found among low-mass galaxies. The average fraction of stellar mass in clusters is ∼0.0014 for M {sub *} > 10{sup 10} M {sub ☉} and can be as large as ∼0.02 for less massive galaxies. These are the first results from the S{sup 4}G sample of galaxies and will be enhanced by the sample of early-type galaxies now being added to S{sup 4}G and complemented by the study of later-type galaxies within S{sup 4}G.

  1. Constraints on Feedback Processes during the Formation of Early-type Galaxies

    Science.gov (United States)

    Trevisan, M.; Ferreras, I.; de La Rosa, I. G.; La Barbera, F.; de Carvalho, R. R.

    2012-06-01

    Galaxies are found to obey scaling relations between a number of observables. These relations follow different trends at the low- and high-mass ends. The processes driving the curvature of scaling relations remain uncertain. In this Letter, we focus on the specific family of early-type galaxies, deriving the star formation histories of a complete sample of visually classified galaxies from Sloan Digital Sky Survey DR7 over the redshift range 0.01 < z < 0.025, covering a stellar mass interval from 109 to 3 × 1011 M ⊙. Our sample features the characteristic "knee" in the surface brightness versus mass distribution at M sstarf ~ 3 × 1010 M ⊙ . We find a clear difference between the age and metallicity distributions of the stellar populations above and beyond this knee, which suggests a sudden transition from a constant, highly efficient mode of star formation in high-mass galaxies, gradually decreasing toward the low-mass end of the sample. At fixed mass, our early-type sample is more efficient in building up the stellar content at early times in comparison to the general population of galaxies, with half of the stars already in place by redshift z ~ 2 for all masses. The metallicity-age trend in low-mass galaxies is not compatible with infall of metal-poor gas, suggesting instead an outflow-driven relation.

  2. CONSTRAINTS ON FEEDBACK PROCESSES DURING THE FORMATION OF EARLY-TYPE GALAXIES

    Energy Technology Data Exchange (ETDEWEB)

    Trevisan, M. [Departamento de Astronomia, Geofisica e Ciencias Atmosfericas, Universidade de Sao Paulo/IAG, Sao Paulo (Brazil); Ferreras, I. [MSSL, University College London, Holmbury St Mary, Dorking, Surrey RH5 6NT (United Kingdom); De La Rosa, I. G. [Instituto de Astrofisica de Canarias (IAC), E-38200 La Laguna, Tenerife (Spain); La Barbera, F. [INAF-Osservatorio Astronomico di Capodimonte, Napoli (Italy); De Carvalho, R. R., E-mail: trevisan@astro.iag.usp.br [Instituto Nacional de Pesquisas Espaciais/MCT, S. J. dos Campos (Brazil)

    2012-06-20

    Galaxies are found to obey scaling relations between a number of observables. These relations follow different trends at the low- and high-mass ends. The processes driving the curvature of scaling relations remain uncertain. In this Letter, we focus on the specific family of early-type galaxies, deriving the star formation histories of a complete sample of visually classified galaxies from Sloan Digital Sky Survey DR7 over the redshift range 0.01 < z < 0.025, covering a stellar mass interval from 10{sup 9} to 3 Multiplication-Sign 10{sup 11} M{sub Sun }. Our sample features the characteristic 'knee' in the surface brightness versus mass distribution at M{sub *} {approx} 3 Multiplication-Sign 10{sup 10} M{sub Sun} . We find a clear difference between the age and metallicity distributions of the stellar populations above and beyond this knee, which suggests a sudden transition from a constant, highly efficient mode of star formation in high-mass galaxies, gradually decreasing toward the low-mass end of the sample. At fixed mass, our early-type sample is more efficient in building up the stellar content at early times in comparison to the general population of galaxies, with half of the stars already in place by redshift z {approx} 2 for all masses. The metallicity-age trend in low-mass galaxies is not compatible with infall of metal-poor gas, suggesting instead an outflow-driven relation.

  3. Effect of Type D personality on medication adherence in early adolescents with asthma.

    Science.gov (United States)

    van de Ven, Monique O M; Witteman, Cilia L M; Tiggelman, Dana

    2013-12-01

    Medication adherence for daily preventive asthma medication is especially low during adolescence. In the present study, we aimed to test whether Type D personality (both as a category and with its constituent components (negative affectivity: NA and social inhibition: SI) separately and in interaction) predicts medication adherence of early adolescents with asthma. In a prospective study, 188 early adolescents with asthma who were prescribed daily preventive asthma medication completed questionnaires on Type D personality, medication adherence, socio-demographic and clinical information, and depressive symptoms in the Spring/Summer of 2011 (T1) and again 12months later (T2). Multiple regression analyses, controlling for demographic and clinical information and for depressive symptoms, were conducted to test whether Type D personality (either as a categorical or dimensional construct) predicted changes in medication adherence over time. Adherence was significantly lower at T2 than at T1 and this decrease was predicted by the categorical construct of Type D personality. Analyses of the two separate dimensions NA and SI and their interaction showed that higher scores on NA at T1 predicted more decrease in adherence over time. Neither SI nor the interaction between NA and SI predicted changes in adherence. This is the first study to test the relationship between Type D personality and medication adherence in adolescents. Although categorical Type D personality predicts mediation adherence of adolescent with asthma over time, dimensional analyses suggest that this is due to negative affectivity only, and not to the combination of negative affectivity and social inhibition. © 2013.

  4. Early-onset type 2 diabetes in a Mexican survey. Results from the National Health and Nutrition Survey 2006

    OpenAIRE

    Aída Jiménez-Corona; Rosalba Rojas; Francisco J Gómez-Pérez; Aguilar-Salinas, Carlos A

    2010-01-01

    OBJECTIVE: To describe the characteristics of patients with type 2 diabetes diagnosed before age 40 (early-onset type 2 diabetes) identified in a nation-wide, population-based study. MATERIALS AND METHODS: The survey was done in Mexico during 2006. Medical history, anthropometric and biochemical measurements were obtained in every subject. RESULTS: Cases diagnosed before (n=181) and after age 40 (n=659) were included. Early-onset type 2 diabetes was present in 13.1% of the previously diagnose...

  5. What types of early gastric cancer are indicated for endoscopic ultrasonography staging of invasion depth?

    Science.gov (United States)

    Watari, Jiro; Ueyama, Shigemitsu; Tomita, Toshihiko; Ikehara, Hisatomo; Hori, Kazutoshi; Hara, Ken; Yamasaki, Takahisa; Okugawa, Takuya; Kondo, Takashi; Kono, Tomoaki; Tozawa, Katsuyuki; Oshima, Tadayuki; Fukui, Hirokazu; Miwa, Hiroto

    2016-08-25

    To clarify the diagnostic efficacy and limitations of endoscopic ultrasonography (EUS) and the characteristics of early gastric cancers (EGCs) that are indications for EUS-based assessment of cancer invasion depth. We retrospectively investigated the cases of 153 EGC patients who underwent conventional endoscopy (CE) and EUS (20 MHz) before treatment. We found that 13.7% were "inconclusive" cases with low-quality EUS images, including all nine of the cases with protruded (0-I)-type EGCs. There was no significant difference in the diagnostic accuracy between CE and EUS. Two significant independent risk factors for misdiagnosis by EUS were identified-ulcer scarring [UL(+); odds ratio (OR) = 4.49, P = 0.003] and non-indication criteria for endoscopic resection (ER) (OR = 3.02, P = 0.03). In the subgroup analysis, 23.1% of the differentiated-type cancers exhibiting SM massive invasion (SM2) invasion (submucosal invasion ≥ 500 μm) by CE were correctly diagnosed by EUS, and 23.1% of the undifferentiated-type EGCs meeting the expanded-indication criteria for ER were correctly diagnosed by EUS. There is no need to perform EUS for UL(+) EGCs or 0-I-type EGCs, but EUS may enhance the pretreatment staging of differentiated-type EGCs with SM2 invasion without UL or undifferentiated-type EGCs revealed by CE as meeting the expanded-indication criteria for ER.

  6. Early atherosclerosis and vascular inflammation in mice with diet-induced type 2 diabetes

    DEFF Research Database (Denmark)

    Bartels, E D; Bang, C A; Nielsen, L B

    2009-01-01

    BACKGROUND: Obesity and type 2 diabetes increase the risk of atherosclerosis. It is unknown to what extent this reflects direct effects on the arterial wall or secondary effects of hyperlipidaemia. MATERIALS AND METHODS: The effect of obesity and type 2 diabetes on the development...... and soluble vascular cell adhesion molecule-1 (sVCAM-1) in both wild-type and apoB transgenic mice. In wild-type mice, plasma very low-density lipoprotein cholesterol (VLDL-C) and low-density lipoprotein cholesterol (LDL-C) were unaffected by fat-feeding. ApoB transgenic mice had mildly elevated plasma LDL...... and the median lesion area was 8.0 times higher than in fat-fed wild-type mice (P = 0.001). Intracellular adhesion molecule-1 staining of the aortic endothelium was most pronounced in the fat-fed apoB transgenic mice. CONCLUSIONS: Our findings suggest that diet-induced type 2 diabetes causes early...

  7. Fluoride alters type I collagen expression in the early stages of odontogenesis.

    Science.gov (United States)

    Maciejewska, I; Spodnik, J H; Domaradzka-Pytel, B; Sidor-Kaczmarek, J; Bereznowski, Z

    2006-11-01

    Fluoride alters the expression and post-translational modifications of extracellular matrix proteins in dentin. The aim of our study was to determine the effects of fluoride on type I collagen expression during the early stages of tooth germ development in rats. Pregnant dams were divided into three groups and fed a standard diet. From the fifth day of pregnancy the three groups received tap water with, respectively, trace amounts of fluoride (C), a low fluoride concentration (FL) or and a high fluoride concentration (FH). Changes in type I collagen expression and distribution were evaluated. The expression of type I collagen was restricted to the extracellular spaces of cells of mesenchymal origin. In the youngest animals the most intense immunoreactivity for type I collagen was detected in predentin of the FL group. Although the intensity of immunostaining increased in proportion to the age of the animals, the largest increase in the groups investigated was detected in the FL group. We concluded that a low concentration of fluoride can act as a stimulator of type I collagen deposition in the extracellular matrix of dentin, while high concentrations of fluoride have an opposite effect, acting as an inhibitor of type I collagen formation in dentin.

  8. Early

    Directory of Open Access Journals (Sweden)

    Kamel Abd Elaziz Mohamed

    2014-04-01

    Conclusion: Early PDT is recommended for patients who require prolonged tracheal intubation in the ICU as outcomes like the duration of mechanical ventilation length of ICU stay and hospital stay were significantly shorter in early tracheostomy.

  9. Bent bone dysplasia (BBD)-FGFR2 type: the radiologic manifestations in early gestation

    Energy Technology Data Exchange (ETDEWEB)

    Handa, Atsuhiko; Okajima, Yuka; Kurihara, Yasuyuki [St. Luke' s International Hospital, Department of Radiology, Tokyo (Japan); Izumi, Noriko; Yamanaka, Michiko [St. Luke' s International Hospital, Department of Integrated Women' s Health, Tokyo (Japan)

    2016-02-15

    Bent bone dysplasia-fibroblast growth factor receptor 2 type (BBD-FGFR2) is a recently identified skeletal dysplasia caused by specific FGFR2 mutations, characterized by craniosynostosis and prenatal bowing of the long bones. Only a few cases have been published. We report an affected fetus terminated at 21 weeks of gestation. The clinical and radiologic manifestations mostly recapitulate previous descriptions; however we suggest additional hallmarks of this disorder in early gestation. These hallmarks include distinctive short, thick clavicles and wavy ribs, as well as vertebral bodies that showed striking anteroposterior shortening. Femoral fractures were also present in our case. Although craniosynostosis is a hallmark of the disease, clinicians should be aware that craniosynostosis might not be readily apparent on plain films early in gestation. (orig.)

  10. The Lack of Very Ultraluminous X-ray Sources in Early-type Galaxies

    CERN Document Server

    Irwin, J A; Athey, A E; Irwin, Jimmy A.; Bregman, Joel N.; Athey, Alex E.

    2004-01-01

    We have searched for ultraluminous X-ray sources (ULXs) in a sample of 28 elliptical and S0 galaxies observed with Chandra. We find that the number of X-ray sources detected at a flux level that would correspond to a 0.3-10 keV X-ray luminosity of ~2 x 10^39 ergs/s or greater (for which we have used the designation very ultraluminous X-ray sources; VULXs) at the distance of each galaxy is equal to the number of expected foreground/background objects. In addition, the VULXs are uniformly distributed over the Chandra field of view rather than distributed like the optical light of the galaxies, strengthening the argument that the high flux sources are unassociated with the galaxies. We have also taken the VULX candidate list of Colbert and Ptak and determined the spatial distribution of VULXs in early-type galaxies and late-type galaxies separately. While the spiral galaxy VULXs are clearly concentrated toward the centers of the galaxies, the early-type galaxy VULXs are distributed randomly over the ROSAT HRI fi...

  11. The cosmic assembly of stellar haloes in massive Early-Type Galaxies

    Science.gov (United States)

    Buitrago, Fernando; Trujillo, Ignacio; Curtis-Lake, Emma; Montes, Mireia; Cooper, Andrew P.; Bruce, Victoria A.; Pérez-González, Pablo G.; Cirasuolo, Michele

    2017-01-01

    Using the exquisite depth of the Hubble Ultra Deep Field (HUDF12 programme) dataset, we explore the ongoing assembly of the outermost regions of the most massive galaxies (M_stellar≥5× 1010 M⊙) at z ≤ 1. The outskirts of massive objects, particularly Early-Types Galaxies (ETGs), are expected to suffer a dramatic transformation across cosmic time due to continuous accretion of small galaxies. HUDF imaging allows us to study this process at intermediate redshifts in 6 massive galaxies, exploring the individual surface brightness profiles out to ˜25 effective radii. We find that 5-20% of the total stellar mass for the galaxies in our sample is contained within 10 values are in close agreement with numerical simulations, and higher than those reported for local late-type galaxies (≲5%). The fraction of stellar mass stored in the outer envelopes/haloes of Massive Early-Type Galaxies increases with decreasing redshift, being 28.7% at = 0.1, 15.1% at = 0.65 and 3.5% at = 2. The fraction of mass in diffuse features linked with ongoing minor merger events is > 1-2%, very similar to predictions based on observed close pair counts. Therefore, the results for our small albeit meaningful sample suggest that the size and mass growth of the most massive galaxies have been solely driven by minor and major merging from z = 1 to today.

  12. The Atlas3D project -- XXVII. Cold Gas and the Colours and Ages of Early-type Galaxies

    CERN Document Server

    Young, L M; Serra, P; Alatalo, K; Bayet, E; Blitz, L; Bois, M; Bournaud, F; Bureau, M; Crocker, A F; Cappellari, M; Davies, R L; Davis, T A; de Zeeuw, P T; Duc, P -A; Emsellem, E; Khochfar, S; Krajnovic, D; Kuntschner, H; McDermid, R M; Morganti, R; Naab, T; Oosterloo, T; Sarzi, M; Weijmans, A -M

    2013-01-01

    We present a study of the cold gas contents of the Atlas3D early-type galaxies, in the context of their optical colours, near-UV colours, and H\\beta\\ absorption line strengths. Early-type (elliptical and lenticular) galaxies are not as gas-poor as previously thought, and at least 40% of local early-type galaxies are now known to contain molecular and/or atomic gas. This cold gas offers the opportunity to study recent galaxy evolution through the processes of cold gas acquisition, consumption (star formation), and removal. Molecular and atomic gas detection rates range from 10% to 34% in red sequence early-type galaxies, depending on how the red sequence is defined, and from 50% to 70% in blue early-type galaxies. Notably, massive red sequence early-type galaxies (stellar masses > 5e10 Msun, derived from dynamical models) are found to have HI masses up to M(HI)/Mstar ~ 0.06 and H_2 masses up to M(H$_2$)/Mstar ~ 0.01. Some 20% of all massive early-type galaxies may have retained atomic and/or molecular gas thro...

  13. Prevalence of Brugada-type ECG pattern and early ventricular repolarization pattern in Tunisian athletes

    Directory of Open Access Journals (Sweden)

    Ouali S

    2011-04-01

    Full Text Available Sana Ouali1, Helmi Ben Salem1, Sami Hammas1, Elyes Neffeti1, Fahmi Remedi1, Abdallah Mahdhaoui2, Essia Boughzela1, Rafik Mankai31Department of Cardiology, Sahloul Hospital, Sousse, Tunisia; 2Department of Cardiology, Farhat Hached, Sousse, Tunisia; 3Central Sports Medicine Centre of El Menzah, TunisiaIntroduction: No data regarding the prevalence of the Brugada-type electrocardiogram (ECG pattern and the early ventricular repolarization pattern (ERP in the North African population were available. The aims of this study were to determine the frequency of Brugada-type ECG pattern and ERP in Tunisia and to evaluate ECG descriptors of ventricular repolarization in a population of athletes.Methods: Over a 2-year period, resting 12-lead ECG recordings were analyzed from athletes (n = 540; 348 males; age 18.3 ± 2.4 years. Brugada-type ECG pattern was defined as Type 1, 2, or 3, and ERP was characterized by an elevation of the J point in the inferior and/or lateral leads. The population was divided into three groups of athletes: ERP group; Brugada-type ECG pattern group; and control group, with neither ERP nor Brugada ECG pattern. Clinical and electrocardiographic parameters were compared among the study groups.Results: Nine subjects (1.66% had a Brugada-type ECG pattern. None of them had the coved-type, 3 (0.6% had the Type 2, and 6 (1.1% had the Type 3. All subjects were asymptomatic. A Brugada-type ECG pattern was observed in seven males. No female had the Type 2 Brugada ECG pattern. ECG parameters were similar among Brugada-type ECG pattern and control athletes. ERP (119 subjects, 22% was obtained in 98 males. Heart rate was lower, the QRS duration shorter and QT and Tpeak–Tend intervals were longer in ERP than control groups.Conclusion: The results indicate that the frequency of the Brugada-type ECG pattern and ERP were respectively 1.66% and 22.00% in athletes, being more prevalent in males. The ERP group experienced shorter QRS duration and

  14. Gamma-ray emission from early-type stars interacting with AGN jets

    Directory of Open Access Journals (Sweden)

    Araudo Anabella T.

    2013-12-01

    Full Text Available We study the interaction of early-type stars with the jets of active galactic nuclei. A bow-shock will form as a consequence of the interaction of the jet with the winds of stars and particles can be accelerated up to relativistic energies in these shocks. We compute the non-thermal radiation produced by relativistic electrons from radio to gamma-rays. This radiation may be significant, and its detection might yield information on the properties of the stellar population in the galaxy nucleus, as well as on the relativistic jet. This emission is expected to be relevant for nearby non-blazar sources.

  15. Early onset hereditary sensory autonomic neuropathy type I and not leprosy

    Directory of Open Access Journals (Sweden)

    Pande Sushil

    2009-01-01

    Full Text Available Hereditary sensory autonomic neuropathies (HSAN are rare forms of chronic neuropathies in children, which lead to severe complications like foot ulcers, mutilations, fractures and deformities. We report an eight years old female who presented with nonhealing perforating ulcer over anterior sole, resorption of terminal portion of right middle finger and hyperhidrosis over back since two years of age. Deep tendon reflexes were absent in lower legs but were preserved in upper limbs. Nerve conduction studies and nerve biopsy confirmed the diagnosis of HSAN, Type I. Early diagnosis of hereditary sensory neuropathy led to significant reduction in morbidity and hence improvement in the quality of life in our patient.

  16. Spectroscopic aperture biases in inside-out evolving early-type galaxies from CALIFA

    Science.gov (United States)

    Gomes, J. M.; Papaderos, P.; Vílchez, J. M.; Kehrig, C.; Iglesias-Páramo, J.; Breda, I.; Lehnert, M. D.; Sánchez, S. F.; Ziegler, B.; Dos Reis, S. N.; Bland-Hawthorn, J.; Galbany, L.; Bomans, D. J.; Rosales-Ortega, F. F.; Walcher, C. J.; García-Benito, R.; Márquez, I.; Del Olmo, A.; Mollá, M.; Marino, R. A.; Catalán-Torrecilla, C.; González Delgado, R. M.; López-Sánchez, Á. R.; Califa Collaboration

    2016-02-01

    Integral field spectroscopy (IFS) studies based on CALIFA survey data have recently revealed ongoing low-level star formation (SF) in the periphery of a small fraction (~10%) of local early-type galaxies (ETGs), witnessing a still ongoing inside-out galaxy growth process. A distinctive property of the nebular component in these ETGs, classified i+, is a structure with two radial zones, the inner of which displays LINER emission with a Hα equivalent width EW(Hα) ≃ 1 Å, the outer (3 Å CSIC).

  17. Excursions into the Evolution of Early-Type Galaxies in Clusters

    CERN Document Server

    López-Cruz, O; Barrientos, L F; Gladders, M D; Yee, H K C; Kodama, T; Lopez-Cruz, Omar; Schade, David; Gladders, Michael D.

    2002-01-01

    Recent observations have revealed that early-type galaxies (ETG) in clusters comprise an old galaxy population that is evolving passively. We review some recent observations from the ground and from HST that show that ETG have undergone a significant amount of luminosity evolution. This evolution is traced by two projections of the fundamental plane (FP): the size-magnitude relation (SMR) and the color-magnitude relation (CMR). We will briefly discuss the relevance of all these results in the context of the universality of the IMF.

  18. 12CO (1-0 AND (2-1 OBSERVATIONS OF ISOLATED EARLY-TYPE GALAXIES

    Directory of Open Access Journals (Sweden)

    M. Chavez

    2009-01-01

    Full Text Available We present 12CO(J=1-0 and 2-1 observations of a small sample of isolated early-type galaxies (ETGs. The data has been collected with the Arizona Radio Observatories (ARO 12 m telescope at Kitt Peak. One object (KIG137 was unambiguously detected in both bands. For this detected galaxy we estimate of the molecular hydrogen mass. These observations are part of a larger project aimed at complementing existing data bases for the study of environmental e ects on the interstellar medium in ETGs.

  19. On early starters and late bloomers: the development of sexual behavior in adolescence across personality types.

    Science.gov (United States)

    Baams, Laura; Overbeek, Geertjan; Dubas, Judith Semon; van Aken, Marcel A G

    2014-01-01

    Little is known about the relationship between personality and sexual development among mid-adolescents. In the current study, we used a person-centered approach to investigate the relation between personality types and the development of sexual behavior. We hypothesized that undercontrolling adolescents would engage in more advanced, casual, and risky sexual behavior compared to their resilient and overcontrolling peers. Data were used from 407 mid-adolescents (Mage = 14.5) followed across four measurement waves spanning 18 months. Results from latent class analyses (LCA) identified the three classical personality types: resilients, undercontrollers, and overcontrollers. Controlling for perceived pubertal timing and biological sex, latent growth curve analyses in Mplus showed that, at baseline, undercontrollers were more sexually experienced and engaged in more casual and risky sexual behavior than resilients and overcontrollers. Although initial levels of sexual behavior differed by personality types, over time increases in sexual behavior occurred at a similar rate across the types. Overall, the current study showed that undercontrolling adolescents are early sexual developers who engage in more advanced, casual, and risky sexual behavior than other adolescents. The implications of these findings for longer-term differences in sexual behavior between personality types in later adolescence are discussed.

  20. The progenitor and early evolution of the Type IIb SN 2016gkg

    CERN Document Server

    Tartaglia, L; Sand, D J; Valenti, S; Smartt, S J; McCully, C; Anderson, J P; Arcavi, I; Elias-Rosa, N; Galbany, L; Gal-Yam, A; Haislip, J B; Hosseinzadeh, G; Howell, D A; Inserra, C; Jha, S W; Kankare, E; Lundqvist, P; Maguire, K; Mattila, S; Reichart, D; Smith, K W; Smith, M; Stritzinger, M; Sullivan, M; Taddia, F; Tomasella, L

    2016-01-01

    We report initial observations and analysis on the Type IIb SN 2016gkg in the nearby galaxy NGC 613. SN 2016gkg exhibited a clear double-peaked light curve during its early evolution, as evidenced by our intensive spectroscopic and photometric follow-up campaign. SN 2016gkg shows strong similarities with other Type IIb SNe, in particular with respect to the \\he emission features observed $\\sim\\,9\\,\\rm{days}$ after explosion in both the optical and near infrared. SN 2016gkg evolved faster than the prototypical Type IIb SN 1993J, with a decline similar to that of SN 2011dh after the first peak. Archival {\\it Hubble Space Telescope} images indicate a pre-explosion source at SN 2016gkg's position, suggesting a progenitor star with a $\\sim$mid F spectral type and initial mass $15-20$\\msun, depending on the distance modulus adopted for NGC 613. Modeling the temperature evolution within $5\\,\\rm{days}$ of explosion, we obtain a progenitor radius of $\\sim\\,60-120$\\rsun, consistent with the spectral type obtained from ...

  1. Cardiovascular morbidity and early mortality cluster in parents of type 1 diabetic patients with diabetic nephropathy

    DEFF Research Database (Denmark)

    Tarnow, L; Rossing, P; Nielsen, F S

    2000-01-01

    (121 of 244 [ approximately 50%] ) as compared with parents of normoalbuminuric type 1 diabetic patients (119 of 269 [approximately 44%]) (P = 0.008 [log-rank test]) partially due to an increase in cardiovascular deaths (48 of 244 [approximately 20%] vs. 42 of 269 [approximately 16%], P....05). In addition, more patients with nephropathy, as compared with the normoalbuminuric group, had at least one parent with fatal/nonfatal cardiovascular disease (46% [95% CI 38-54] vs. 36% [28-44], P = 0.05). Fathers of patients homozygous for the I-allele of the ACE/ID polymorphism had significantly less...... myocardial infarction as compared with other genotypes (P = 0.03), regardless of the nephropathic state of the offspring. CONCLUSIONS: Cardiovascular morbidity and early mortality clusters in parents of type 1 diabetic patients with diabetic nephropathy The ACE/ID polymorphism helps explain the increased...

  2. PROJECTED ROTATIONAL VELOCITIES OF 136 EARLY B-TYPE STARS IN THE OUTER GALACTIC DISK

    Energy Technology Data Exchange (ETDEWEB)

    Garmany, C. D.; Glaspey, J. W. [National Optical Astronomy Observatory, 950 N. Cherry Ave., Tucson, AZ 85719 (United States); Bragança, G. A.; Daflon, S.; Fernandes, M. Borges; Cunha, K. [Observatório Nacional-MCTI, Rua José Cristino, 77. CEP: 20921-400, Rio de Janeiro, RJ (Brazil); Oey, M. S. [University of Michigan, Department of Astronomy, 311 West Hall, 1085 S. University Ave., Ann Arbor, MI: 48109-1107 (United States); Bensby, T., E-mail: garmany@noao.edu [Lund Observatory, Department of Astronomy and Theoretical Physics, Box 43, SE-22100, Lund (Sweden)

    2015-08-15

    We have determined projected rotational velocities, v sin i, from Magellan/MIKE echelle spectra for a sample of 136 early B-type stars having large Galactocentric distances. The target selection was done independently of their possible membership in clusters, associations or field stars. We subsequently examined the literature and assigned each star as Field, Association, or Cluster. Our v sin i results are consistent with a difference in aggregate v sin i with stellar density. We fit bimodal Maxwellian distributions to the Field, Association, and Cluster subsamples representing sharp-lined and broad-lined components. The first two distributions, in particular, for the Field and Association are consistent with strong bimodality in v sin i. Radial velocities are also presented, which are useful for further studies of binarity in B-type stars, and we also identify a sample of possible new double-lined spectroscopic binaries. In addition, we find 18 candidate Be stars showing emission at Hα.

  3. WASP-26b: A 1-Jupiter-mass planet around an early-G-type star

    CERN Document Server

    Smalley, B; Cameron, A Collier; Gillon, M; Hellier, C; Lister, T A; Maxted, P F L; Queloz, D; Triaud, A H M J; West, R G; Bentley, S J; Enoch, B; Pepe, F; Pollacco, D L; Segransan, D; Smith, A M S; Southworth, J; Udry, S; Wheatley, P J; Wood, P L; Bento, J

    2010-01-01

    We report the discovery of WASP-26b, a moderately over-sized Jupiter-mass exoplanet transiting its 11.3-magnitude early-G-type host star (1SWASP J001824.70-151602.3; TYC 5839-876-1) every 2.7566 days. A simultaneous fit to transit photometry and radial-velocity measurements yields a planetary mass of 1.02 +/- 0.03 M_Jup and radius of 1.32 +/- 0.08 R_Jup. The host star, WASP-26, has a mass of 1.12 +/- 0.03 M_sun and a radius of 1.34 +/- 0.06 R_sun and is in a visual double with a fainter K-type star. The two stars are at least a common-proper motion pair with a common distance of around 250 +/- 15 pc and an age of 6 +/- 2 Gy.

  4. Cardiovascular morbidity and early mortality cluster in parents of type 1 diabetic patients with diabetic nephropathy

    DEFF Research Database (Denmark)

    2000-01-01

    myocardial infarction as compared with other genotypes (P = 0.03), regardless of the nephropathic state of the offspring. CONCLUSIONS: Cardiovascular morbidity and early mortality clusters in parents of type 1 diabetic patients with diabetic nephropathy The ACE/ID polymorphism helps explain the increased......OBJECTIVE: A familial predisposition was proposed to be a determinant of the increased morbidity and mortality from cardiovascular disease in type 1 diabetic patients with diabetic nephropathy. The insertion allele of an insertion/deletion polymorphism in the ACE (ACE/ID) gene seems to protect.......05). In addition, more patients with nephropathy, as compared with the normoalbuminuric group, had at least one parent with fatal/nonfatal cardiovascular disease (46% [95% CI 38-54] vs. 36% [28-44], P = 0.05). Fathers of patients homozygous for the I-allele of the ACE/ID polymorphism had significantly less...

  5. Early-type massive stars in Carina Nebula within the Gaia-ESO Survey.

    Science.gov (United States)

    Berlanas, S. R.; Herrero, A.; Martins, F.; Simón-Díaz, S.; Mahy, L.; Blomme, R.; GES WG-13

    2017-03-01

    The Gaia-ESO Survey (GES) is obtaining high quality spectra of ˜ 10^5 stars in our Galaxy, providing an homogeneous and unique overview of all the main components of the Milky Way, its formation history and the evolution of young, mature and ancient Galactic populations. Our group is in charge of the early-type massive stars that define the youngest population in the survey. In this contribution, we present the results of the quantitative spectroscopic analysis of O-type stars in the Carina Nebula within the Gaia-ESO Survey. For this aim, we have used FASTWIND and CMFGEN stellar atmosphere codes, providing stellar parameters for the current sample (GES data release iDR4).

  6. Type II cytokeratin gene expression is indicative of early cell differentiation in the chick embryo

    Energy Technology Data Exchange (ETDEWEB)

    Charlebois, T.S.

    1988-01-01

    Embryonic development in vertebrates appears to involve a series of inductive tissue interactions that lead to regional specializations, which eventually become elaborated in the basic body plan of the embryo. The inductive interactions leading to early regionalization of the embryo are often particularly difficult to evaluate because of the absence of available morphological or biochemical evidence that such events have occurred. In the 36 hour chick embryo, the regional subdivision of the early ectoderm is evidence by a marked lens-forming bias in the head ectoderm, which is absent in the presumptive dorsal epidermis of the trunk region. As a strategy for isolating genes whose differential expression might reflect this regional subdivision, a cDNA library from 36 hour embryos was prepared and screened for differential hybridization to ({sup 32}P)cDNA probes synthesized using template RNA isolated from 36 hour head ectoderm and trunk ectoderm. A cDNA clone (T4) was isolated which hybridizes to transcripts present at much higher levels in trunk ectoderm than in head ectoderm. Partial nucleotide and deduced amino acid sequences of this clone indicate that it represents a gene encoding a type II cytokeratin. The distribution of transcripts complementary to the T4 probe was evaluated in early embryos using RNA gel blot analysis and in situ hybridization to tissue sections.

  7. The Resettlement of the British Landscape: Towards a chronology of Early Mesolithic lithic assemblage types

    Directory of Open Access Journals (Sweden)

    Chantal Conneller

    2016-12-01

    Full Text Available During the Upper Palaeolithic Britain was visited intermittently, perhaps only on a seasonal basis, by groups often operating at the margins of their range. The Early Mesolithic, by contrast, witnessed the start of the permanent occupation of the British landscape, with certain key sites showing evidence for long-lasting occupation from the very start of the period. However, currently our understanding of the timing and tempo of the Mesolithic colonisation and infilling of the landscape is limited because of the paucity of precise radiocarbon measurements. In this contribution we assess and model existing radiocarbon measurements to refine current typochronological models for the first two millennia of the Holocene. This is a necessary first step towards understanding the Mesolithic resettlement of the British Isles. Our results throw new light on the relationship between the last Upper Palaeolithic 'Long Blade' industries and early Mesolithic assemblages, as well as refining our understanding of the chronology of early Mesolithic assemblage types. Our data also suggest regional patterning to the timing of Mesolithic settlement and throws new light on issues of population movement and adoption of new technologies.

  8. The SLUGGS Survey: The Assembly Histories of Individual Early-type Galaxies

    CERN Document Server

    Forbes, Duncan A; Pastorello, Nicola; Foster, Caroline; Brodie, Jean P; Strader, Jay; Usher, Christopher; Pota, Vincenzo

    2016-01-01

    Early-type (E and S0) galaxies may have assembled via a variety of different evolutionary pathways. Here we investigate these pathways by comparing the stellar kinematic properties of 24 early-type galaxies from the SLUGGS survey with the hydrodynamical simulations of Naab et al. (2014). In particular, we use the kinematics of starlight up to 4 effective radii (R$_e$) as diagnostics of galaxy inner and outer regions, and assign each galaxy to one of six Naab et al. assembly classes. The majority of our galaxies (14/24) have kinematic characteristics that indicate an assembly history dominated by gradual gas dissipation and accretion of many gas-rich minor mergers. Three galaxies, all S0s, indicate that they have experienced gas-rich major mergers in their more recent past. One additional elliptical galaxy is tentatively associated with a gas-rich merger which results in a remnant galaxy with low angular momentum. Pathways dominated by gas-poor (major or minor) mergers dominate the mass growth of six galaxies....

  9. Central stellar populations of early-type galaxies in low-density environments

    CERN Document Server

    Collobert, M; Davies, R L; Kuntschner, H; Colless, M; Colless, Matthew

    2006-01-01

    We have investigated the properties of a volume and magnitude limited sample of nearby early type galaxies that were carefully selected from the AAO two degree field galaxy redshift survey. We used images from the DSS to confirm the E/S0 morphologies, and augmented this sample with field galaxies from Colbert et al. 2001. We present spectroscopic observations of 22 galaxies from the combined sample, from which central velocity dispersions and the Lick stellar population indices were measured. After carefully correcting the spectra for nebular emission we derived luminosity-weighted ages, metallicities, and alpha-element abundance ratios. We compare these isolated galaxies with samples of early-type galaxies in the Virgo and Coma clusters, and also with the sample of galaxies in low-density regions of Kuntschner et al. (2002). We find that galaxies in low-density environments are younger and have a greater spread of ages compared to cluster galaxies. They also show a wider range of metallicities at a given vel...

  10. Enviromental Effects on Internal Color Gradients of Early-Type Galaxies

    Science.gov (United States)

    La Barbera, F.; de Carvalho, R. R.; Gal, R. R.; Busarello, G.; Haines, C. P.; Mercurio, A.; Merluzzi, P.; Capaccioli, M.; Djorgovski, S. G.

    2007-05-01

    One of the most debated issues of observational and theoretical cosmology is that of how the environment affects the formation and evolution of galaxies. To gain new insight into this subject, we have derived surface photometry for a sample of 3,000 early-type galaxies belonging to 163 clusters with different richness, spanning a redshift range of 0.05 to 0.25. This large data-set is used to analyze how the color distribution inside galaxies depends on several parameters, such as cluster richness, local galaxy density, galaxy luminosity and redshift. We find that the internal color profile of galaxies strongly depends on the environment where galaxies reside. Galaxies in poor and rich clusters are found to follow two distinct trends in the color gradient vs. redshift diagram, with color gradients beeing less steep in rich rather than in poor clusters. No dependence of color gradients on galaxy luminosity is detected both for poor and rich clusters. We find that color gradients strongly depend on local galaxy density, with more shallow gradients in high density regions. Interestingly, this result holds only for low richness clusters, with color gradients of galaxies in rich clusters showing no dependence on local galaxy density. Our results support a reasonable picture whereby young early-type galaxies form in a dissipative collapse process, and then undergo increased (either major or minor) merging activity in richer rather than in poor clusters.

  11. Strong Gravitational Lensing and the Stellar IMF of Early-type Galaxies

    CERN Document Server

    Leier, Dominik; Saha, Prasenjit; Charlot, Stéphane; Bruzual, Gustavo; La Barbera, Francesco

    2015-01-01

    The stellar initial mass function is an important ingredient in galaxy formation, mainly linking the luminosity of a galaxy to its stellar mass, and driving chemical enrichment. In recent years there has been an ongoing discussion about systematic variations of the IMF in early-type galaxies and its connection with possible drivers such as velocity dispersion or metallicity. Strong gravitational lensing over galaxy scales in combination with photometric and spectroscopic data provides a powerful method to constrain the stellar mass-to-light ratio and hence the functional form of the IMF. We combine photometric and spectroscopic constraints from the latest set of population synthesis models of Charlot & Bruzual, including a varying IMF, with a non-parametric analysis of the lensing mass in a sample of 18 early-type lens galaxies from the SLACS survey, with velocity dispersions in the range 200-300 km/s. We find that very bottom-heavy IMFs are excluded. However, the upper limit to the IMF slope ($\\mu \\lesss...

  12. Evidence for dark matter contraction and a Salpeter IMF in a massive early-type galaxy

    CERN Document Server

    Sonnenfeld, Alessandro; Gavazzi, Raphael; Marshall, Philip J; Auger, Mattew W; Suyu, Sherry H; Koopmans, Leon V E; Bolton, Adam S

    2011-01-01

    Stars and dark matter account for most of the mass of early-type galaxies, but uncertainties in the stellar population and the dark matter profile make it challenging to distinguish between the two components. Nevertheless, precise observations of stellar and dark matter are extremely valuable for testing the many models of structure formation and evolution. We present a measurement of the stellar mass and inner slope of the dark matter halo of a massive early-type galaxy at $z=0.222$. The galaxy is the foreground deflector of the double Einstein ring gravitational lens system SDSSJ0946+1006, also known as the "Jackpot". By combining the tools of lensing and dynamics, we first constrain the mean slope of the total mass density profile ($\\rho_{\\rm{tot}}\\propto r^{-\\gamma'}$) within the radius of the outer ring to be $\\gamma' = 1.98\\pm0.02\\pm0.01$. Then we obtain a bulge-halo decomposition, assuming a power-law form for the dark matter halo. Our analysis yields $\\gamma_{\\rm{DM}} = 1.7\\pm0.2$ for the inner slope...

  13. Early Cardiac Dysfunction in the Type 1 Diabetic Heart Using Speckle-Tracking Based Strain Imaging

    Science.gov (United States)

    Shepherd, Danielle L.; Nichols, Cody E.; Croston, Tara L.; McLaughlin, Sarah L.; Petrone, Ashley B.; Lewis, Sara E.; Thapa, Dharendra; Long, Dustin M.; Dick, Gregory M.; Hollander, John M.

    2016-01-01

    Enhanced sensitivity in echocardiographic analyses may allow for early detection of changes in cardiac function beyond the detection limits of conventional echocardiographic analyses, particularly in a small animal model. The goal of this study was to compare conventional echocardiographic measurements and speckle-tracking based strain imaging analyses in a small animal model of type 1 diabetes mellitus. Conventional analyses revealed differences in ejection fraction, fractional shortening, cardiac output, and stroke volume in diabetic animals relative to controls at 6-weeks post-diabetic onset. In contrast, when assessing short- and long-axis speckle-tracking based strain analyses, diabetic mice showed changes in average systolic radial strain, radial strain rate, radial displacement, and radial velocity, as well as decreased circumferential and longitudinal strain rate, as early as 1-week post-diabetic onset and persisting throughout the diabetic study. Further, we performed regional analyses for the LV and found that the free wall region was affected in both the short- and long-axis when assessing radial dimension parameters. These changes began 1-week post-diabetic onset and remained throughout the progression of the disease. These findings demonstrate the use of speckle-tracking based strain as an approach to elucidate cardiac dysfunction from a global perspective, identifying left ventricular cardiac regions affected during the progression of type 1 diabetes mellitus earlier than contractile changes detected by conventional echocardiographic measurements. PMID:26654913

  14. Constraints on feedback processes during the formation of early-type galaxies

    CERN Document Server

    Trevisan, Marina; de la Rosa, Ignacio; La Barbera, Francesco; de Carvalho, Reinaldo

    2012-01-01

    Galaxies are found to obey scaling relations between a number of observables. These relations follow different trends at the low- and the high-mass ends. The processes driving the curvature of scaling relations remain uncertain. In this letter, we focus on the specific family of early-type galaxies, deriving the star formation histories of a complete sample of visually classified galaxies from SDSS-DR7 over the redshift range 0.01early-type sample is more efficient in building up the stellar content...

  15. Structural Properties of Early-Type Galaxies from the SDSS DR2

    Institute of Scientific and Technical Information of China (English)

    Feng-Shan Liu; Zu-Gan Deng; Hong Wu; Xiao-Yang Xia

    2008-01-01

    Two-dimensional bulge/disk light decomposition with GIM2D in both the r-and g-bands has been applied to a sample of 129 early-type galaxies brighter than 13.5 magnitude in the r-band,selected from the Sloan Digital Sky Survey Data Release 2.Intensity-weighted Fourier coefficient (a4/a) was also derived for each sample galaxy.Our analysis shows that and between bulge and disk scale sizes.Isophotal shape parameter (a4/a) is not correlated with BIT and nB.Both bulge and disk components satisfy a color-magnitude relation.The k space Fundamental Plane analysis shows that galaxies with larger B/T tend to lie tighter and closer to the line of k1+k2=8 (the so-called "zone of avoidance") than the galaxies with smaller B/T.It indicates that existence of the disk component may lead to scatter of the distribution on the Fundamental Plane.Our analysis also shows that k1+k2 correlates with (y-r) color and B/T,but does not correlate with (a4/a) for early-type galaxies.The fitted parameters and other retrieved parameters used in this paper for all sample galaxies are available online.

  16. The effect of hot gas in early-type galaxies on the cosmic microwave background

    Science.gov (United States)

    Trester, Jeffrey J.; Canizares, Claude R.

    1989-01-01

    The effects on the cosmic microwave background which are due to Compton scattering by the hot gas contained in early-type galaxies (the Sunyaev-Zeldovich effect) are computed. Using the known properties of the gas deduced from X-ray observations, it is found that the fractional attenuation DeltaT/T at the center of a gas-rich galaxy is likely to be less than 10 to the -5th, which is just below current limits of detectability. A distribution function is derived for the attenuation which is due to a population of early-type galaxies out to some redshift and the expected rms fluctuations in the background on subarcmin scales are computed. These fluctuations are comparable to those intrinsic to the microwave background in the 'cold dark matter' scenario on these angular scales, but they fall orders of magnitude below the detection limits and below the level of fluctuations expected from nonlinear density perturbations at the epoch of galaxy formation.

  17. Globular clusters kinematics and dynamical models of the massive early-type galaxy NGC 1399

    Science.gov (United States)

    Samurović, S.

    2016-06-01

    We analyze the dynamical models of the massive early-type galaxy NGC 1399, the central galaxy of the Fornax cluster. We use the sample of 790 globular clusters as tracers of gravitational potential and we first extract the kinematics, which is then dynamically modeled. We find that the velocity dispersion remains high and approximately constant throughout the whole galaxy and that the departures from the Gaussian distribution of the orbits are not large. We use the spherical Jeans equation in both Newtonian and MOND approaches, assuming three cases of orbital anisotropies: we study isotropic, tangentially and radially anisotropic models in order to establish the best-fitting values of the mass-to-light ratios. We found that in the Newtonian approximation a significant amount of dark matter is needed and that Navarro-Frenk-White (NFW) model with a dark halo provides a satisfactory description of the kinematics of NGC 1399. We tested three MOND models (standard, simple and toy) and found that none of them can provide a fit of the velocity dispersion profile without the inclusion of dark matter. Finally, using our findings, we placed the galaxy NGC 1399 within the context of other observed early-type galaxies and discuss its location among them.

  18. Dozens of compact and high dispersion early-type galaxies in Sloan Digital Sky Survey

    CERN Document Server

    Saulder, Christoph; Mieske, Steffen

    2015-01-01

    Aims. We aim at finding candidates of potential survivors of high-redshift compact galaxies in SDSS, as targets for more detailed follow-up observations. Methods. From the virial theorem it is expected that for a given mass, compact galaxies have stellar velocity dispersion higher than the mean due to their smaller sizes. Therefore velocity dispersion coupled with size (or mass) is an appropriate method to select relics, independent of the stellar population properties. Based on these consideration we design a set of criteria using distribution of early-type galaxies from SDSS on the log$_{10}$(R$_{0}$)-log$_{10}$($\\sigma_{0}$) plane to find the most extreme objects on it. Results. We find 76 galaxies at 0.05 < z < 0.2, which have properties similar to the typical quiescent galaxies at high redshift. We study how well these galaxies fit on well-known local universe relations of early-type galaxies such as the fundamental plane, the red sequence or mass-size relations. As expected from the selection crit...

  19. Evolution of the Early-Type Galaxy Fraction in Clusters since z = 0.8

    CERN Document Server

    Simard, Luc; Desai, Vandana; Dalcanton, Julianne J; von der Linden, Anja; Poggianti, Bianca M; White, Simon D M; Aragon-Salamanca, Alfonso; De Lucia, Gabriella; Halliday, Claire; Jablonka, Pascale; Milvang-Jensen, Bo; Saglia, Roberto P; Pello, Roser; Rudnick, Gregory H; Zaritsky, Dennis

    2009-01-01

    We study the morphological content of a large sample of high-redshift clusters to determine its dependence on cluster mass and redshift. Quantitative morphologies are based on bulge+disk decompositions of cluster and field galaxies on deep VLT/FORS2 images of 18 optically-selected clusters at 0.45 < z < 0.80 from the ESO Distant Cluster Survey (EDisCS). Morphological content is given by the early-type galaxy fraction f_et, and early-type galaxies are selected based on their bulge fraction and image smoothness. A set of 158 SDSS clusters is analyzed exactly as the EDisCS sample to provide a robust local comparison. Our main results are: (1) f_et values for the SDSS and EDisCS clusters exhibit no clear trend as a function of sigma. (2) Mid-z EDisCS clusters around sigma = 500 km/s have f_et ~= 0.5 whereas high-z EDisCS clusters have f_et ~= 0.4 (~25% increase over 2 Gyrs). (3) There is a marked difference in the morphological content of EDisCS and SDSS clusters. None of the EDisCS clusters have f_et great...

  20. Early diagnostics and incidence of diabetic nephropathy depending on type 1 diabetes mellitus duration

    Directory of Open Access Journals (Sweden)

    V.A. Maslianko

    2017-05-01

    Full Text Available The objective — to establish the incidence of diabetic nephropathy (DN depending on duration of type 1 diabetes mellitus (DM, and also the content of cystatin С as a marker of early kidney damage. Materials and methods. Twenty eight patients with type 1 DM were enrolled in prospective study (11 men and 17 women aged 34.8 ± 7.2 years. Clinical and functional examination included the standard evaluation of renal function, and also the study of serum level of cystatin С. Results. In 17 out of 28 patients, the indexes of glomerular filtration rate calculated using the formulas of CKD-ЕРIcreat and CKD-ЕРIcys, indicated the different stages of chronic kidneys disease. Conclusions. Determination of cystatin C level and calculation of glomerular filtration rate using this index allows diagnosing the preclinical stages of kidney dysfunction in patients with type 1 DM in the normal creatinine level in the blood and without decline in glomerular filtration rate calculated using creatinine value. According to a retrospective study, the incidence and severity of DN in patients with type 1 DM increases with disease duration of more than 10 years.

  1. Nebular emission and the Lyman continuum photon escape fraction in CALIFA early-type galaxies

    CERN Document Server

    Papaderos, P; Vilchez, J M; Kehrig, C; Lehnert, M D; Ziegler, B; Sanchez, S F; Husemann, B; Monreal-Ibero, A; Garcia-Benito, R; Bland-Hawthorn, J; Coritjo, C; de Lorenzo-Caceres, A; del Olmo, A; Falcon-Barroso, J; Galbany, L; Iglesias-Paramo, J; Lopez-Sanchez, A R; Marquez, I; Molla, M; Mast, D; van de Ven, G; Wisotzki, L

    2013-01-01

    We use deep integral field spectroscopy data from the CALIFA survey to study the warm interstellar medium (WIM) of 32 nearby early-type galaxies (ETGs). We propose a tentative subdivision of our sample ETGs into two groups, according to their Ha equivalent width (EW) and Lyman continuum (LyC) photon escape fraction (PLF). Type i ETGs show nearly constant EWs and a PLF~0, suggesting that photoionization by post-AGB stars is the main driver of their faint extranuclear nebular emission. Type ii ETGs are characterized by very low, outwardly increasing EWs, and a PLF as large as ~0.9 in their centers. Such properties point to a low, and inwardly decreasing WIM density and/or volume filling factor. We argue that, because of extensive LyC photon leakage, emission-line luminosities and EWs are reduced in type ii ETG nuclei by at least one order of magnitude. Consequently, the line weakness of these ETGs is by itself no compelling evidence for their containing merely "weak" (sub-Eddington accreting) active galactic nu...

  2. GROWTH AND MOTOR DEVELOPMENT IN FETUSES OF WOMEN WITH TYPE-1 DIABETES .1. EARLY GROWTH-PATTERNS

    NARCIS (Netherlands)

    MULDER, EJH; VISSER, GHA

    1991-01-01

    Early embryonic and fetal growth were followed longitudinally in 23 women with type-1 diabetes to investigate whether there was any evidence of early growth delay and, if so, when it originated and when catch-up growth occurred. Weekly crown-rump length (CRL) measurements were taken between 7 and 14

  3. Atrial Natriuretic Peptide (ANP) in early pregnancy is associated with development of preeclampsia in type 1 diabetes

    DEFF Research Database (Denmark)

    Nielsen, Lene Ringholm; Pedersen-Bjergaard, Ulrik; Thorsteinsson, Birger;

    2011-01-01

    The vasoactive markers of cardiac overload Atrial Natriuretic Peptide (ANP) and Brain Natriuretic Peptide (BNP) are elevated in preeclampsia. This study documents higher ANP concentrations as early as at 9 weeks in type 1 diabetic women subsequently developing preeclampsia suggesting...... that preeclampsia is associated with cardiovascular changes in early pregnancy....

  4. GROWTH AND MOTOR DEVELOPMENT IN FETUSES OF WOMEN WITH TYPE-1 DIABETES .1. EARLY GROWTH-PATTERNS

    NARCIS (Netherlands)

    MULDER, EJH; VISSER, GHA

    1991-01-01

    Early embryonic and fetal growth were followed longitudinally in 23 women with type-1 diabetes to investigate whether there was any evidence of early growth delay and, if so, when it originated and when catch-up growth occurred. Weekly crown-rump length (CRL) measurements were taken between 7 and 14

  5. Type I TARPs promote dendritic growth of early postnatal neocortical pyramidal cells in organotypic cultures.

    Science.gov (United States)

    Hamad, Mohammad I K; Jack, Alexander; Klatt, Oliver; Lorkowski, Markus; Strasdeit, Tobias; Kott, Sabine; Sager, Charlotte; Hollmann, Michael; Wahle, Petra

    2014-04-01

    The ionotropic α-amino-3-hydroxy-5-methyl-4-isoxazole propionate glutamate receptors (AMPARs) have been implicated in the establishment of dendritic architecture. The transmembrane AMPA receptor regulatory proteins (TARPs) regulate AMPAR function and trafficking into synaptic membranes. In the current study, we employ type I and type II TARPs to modulate expression levels and function of endogenous AMPARs and investigate in organotypic cultures (OTCs) of rat occipital cortex whether this influences neuronal differentiation. Our results show that in early development [5-10 days in vitro (DIV)] only the type I TARP γ-8 promotes pyramidal cell dendritic growth by increasing spontaneous calcium amplitude and GluA2/3 expression in soma and dendrites. Later in development (10-15 DIV), the type I TARPs γ-2, γ-3 and γ-8 promote dendritic growth, whereas γ-4 reduced dendritic growth. The type II TARPs failed to alter dendritic morphology. The TARP-induced dendritic growth was restricted to the apical dendrites of pyramidal cells and it did not affect interneurons. Moreover, we studied the effects of short hairpin RNA-induced knockdown of endogenous γ-8 and showed a reduction of dendritic complexity and amplitudes of spontaneous calcium transients. In addition, the cytoplasmic tail (CT) of γ-8 was required for dendritic growth. Single-cell calcium imaging showed that the γ-8 CT domain increases amplitude but not frequency of calcium transients, suggesting a regulatory mechanism involving the γ-8 CT domain in the postsynaptic compartment. Indeed, the effect of γ-8 overexpression was reversed by APV, indicating a contribution of NMDA receptors. Our results suggest that selected type I TARPs influence activity-dependent dendritogenesis of immature pyramidal neurons.

  6. Atrial Natriuretic Peptide (ANP) in early pregnancy is associated with development of preeclampsia in type 1 diabetes

    DEFF Research Database (Denmark)

    Nielsen, Lene Ringholm; Pedersen-Bjergaard, Ulrik; Thorsteinsson, Birger

    2011-01-01

    The vasoactive markers of cardiac overload Atrial Natriuretic Peptide (ANP) and Brain Natriuretic Peptide (BNP) are elevated in preeclampsia. This study documents higher ANP concentrations as early as at 9 weeks in type 1 diabetic women subsequently developing preeclampsia suggesting that preecla......The vasoactive markers of cardiac overload Atrial Natriuretic Peptide (ANP) and Brain Natriuretic Peptide (BNP) are elevated in preeclampsia. This study documents higher ANP concentrations as early as at 9 weeks in type 1 diabetic women subsequently developing preeclampsia suggesting...

  7. The Evolution of Early-type Field Galaxies Selected from a NICMOS Map of the Hubble Deep Field North

    Energy Technology Data Exchange (ETDEWEB)

    Somerville, R; Stanford, S A; Budavari, T; Conselice, C J

    2004-03-03

    The redshift distribution of well-defined samples of distant early-type galaxies offers a means to test the predictions of monolithic and hierarchical galaxy formation scenarios. NICMOS maps of the entire Hubble Deep Field North in the F110W and F160W filters, when combined with the available WFPC2 data, allow us to calculate photometric redshifts and determine the morphological appearance of galaxies at rest-frame optical wavelengths out to z {approx} 2.5. Here we report results for two subsamples of early-type galaxies, defined primarily by their morphologies in the F160W band, which were selected from the NICMOS data down to H{sub 160AB} < 24.0. A primary subsample is defined as the 34 galaxies with early-type galaxy morphologies and early-type galaxy spectral energy distributions. The secondary subsample is defined as those 42 objects which have early-type galaxy morphologies with non-early type galaxy spectral energy distributions. The observed redshift distributions of our two early-type samples do not match that predicted by a monolithic collapse model, which shows an overabundance at z > 1.5. A (V/V{sub max}) test confirms this result. When the effects of passive luminosity evolution are included in the calculation, the mean value of Vmax for the primary sample is 0.22 {+-} 0.05, and 0.31 {+-} 0.04 for all the early-types. A hierarchical formation model better matches the redshift distribution of the HDF-N early-types at z > 1.5, but still does not adequately describe the observed early-types. The hierarchical model predicts significantly bluer colors on average than the observed early-type colors, and underpredicts the observed number of early-types at z {approx} 2. Though the observed redshift distribution of the early-type galaxies in our HDF-NICMOS sample is better matched by a hierarchical galaxy formation model, the reliability of this conclusion is tempered by the restricted sampling area and relatively small number of early-type galaxies selected by

  8. Initiating Characteristics of Early-onset Type 2 Diabetes Mellitus in Chinese Patients

    Institute of Scientific and Technical Information of China (English)

    Hui Yu; Li-Fang Xie; Kang Chen; Gang-Yi Yang; Xiao-Yan Xing; Jia-Jun Zhao; Tian-Pei Hong

    2016-01-01

    Background:Type 2 diabetes mellitus (T2DM) has traditionally been considered to affect mainly the elderly;however,the age at diagnosis has gradually reduced in recent years.Although the incidence of young-onset T2DM is increasing,it is still not fully clear the onset characteristics and risk factors of early-onset T2DM.The aim of this study was to describe the initiating characteristics of early-onset T2DM in Chinese patients and evaluate the risk factors for diabetes mellitus.Methods:This cross-sectional controlled study was performed using a questionnaire survey method in outpatients of multiple centers in China.A total of 1545 patients with T2DM with an age at onset of<40 years were included,and the control group consisted of subjects aged <40 years with normal blood glucose level.Results:In patients with young-onset T2DM,the mean age and initial hemoglobin 1Ac at diagnosis were 32.96 ± 5.40 years and 9.59 ± 2.71%,respectively.Most of the patients were obese,followed irregular diet pattern and sedentary lifestyle,had life or work pressure,and had a family history of diabetes mellitus.Compared with subjects with normal blood glucose level,logistic regression analysis showed that waist-to-hip ratio (odds ratio [OR] 446.99,95% confidence interval [CI] 42.37-4714.87),family history of diabetes mellitus (OR 23.46,CI14.47-38.03),dyslipidemia (OR 2.65,CI 1.54-4.56),diastolic blood pressure (OR 1.02,CI 1.00-1.04),and body mass index (OR 0.95,CI 0.92-0.99) are independent factors for early-onset T2DM.Conclusions:We observed that abdominal obesity,family history of diabetes mellitus,and medical history of hypertension and dyslipidemia are independent risk factors for early-onset T2DM.It is,therefore,necessary to apply early lifestyle intervention in young people with risk of diabetes mellitus.

  9. Dark matter and IMF normalization in Virgo dwarf early-type galaxies

    Science.gov (United States)

    Tortora, C.; La Barbera, F.; Napolitano, N. R.

    2016-01-01

    In this work, we analyse the dark matter (DM) fraction, fDM, and mass-to-light ratio mismatch parameter, δIMF (computed with respect to a Milky Way-like initial mass function), for a sample of 39 dwarf early-type galaxies in the Virgo cluster. Both fDM and δIMF are estimated within the central (one effective radius) galaxy regions, with a Jeans dynamical analysis that relies on galaxy velocity dispersions, structural parameters, and stellar mass-to-light ratios from the SMAKCED survey. In this first attempt to constrain, simultaneously, the initial mass function (IMF) normalization and the DM content, we explore the impact of different assumptions on the DM model profile. On average, for an Navarro, Frenk & White (NFW) profile, the δIMF is consistent with a Chabrier-like normalization ({δ _IMF}˜ 1), with {f_DM}˜ 0.35. One of the main results of this work is that for at least a few systems the δIMF are heavier than the Milky Way-like value (i.e. either top- or bottom-heavy). When introducing tangential anisotropy, larger δIMF and smaller fDM are derived. Adopting a steeper concentration-mass relation than that from simulations, we find lower δIMF ( ≲ 1) and larger fDM. A constant M/L profile with null fDM gives the heaviest δIMF (˜2). In the MONDian framework, we find consistent results to those for our reference NFW model. If confirmed, the large scatter of δIMF for dEs would provide (further) evidence for a non-universal IMF in early-type systems. On average, our reference fDM estimates are consistent with those found for low-σe (˜ 100 km s^{-1}) early-type galaxies (ETGs). Furthermore, we find fDM consistent with values from the SMAKCED survey, and find a double-value behaviour of fDM with stellar mass, which mirrors the trend of dynamical M/L and global star formation efficiency (from abundance matching estimates) with mass.

  10. Localized type Volkmann's contracture treated with tendon transfer and tension-reduced early mobilization

    Science.gov (United States)

    Kaji, Yoshio; Nakamura, Osamu; Yamaguchi, Konosuke; Tobiume, Sachiko; Yamamoto, Tetsuji

    2017-01-01

    Abstract Rationale: For localized type Volkmann's contracture, in which degeneration of the flexor digitorum profundus (FDP) muscle to one or two fingers and restriction of finger extension occur, dissection or excision of the affected muscle is usually recommended. However, these surgical procedures need relatively wide exposure of the muscle, because the FDP muscle is in the deep portion of the forearm. Patient concerns: In this report, the case of a 35-year-old woman with localized type Volkmann's contracture is presented. Her left forearm had been compressed with an industrial roller 4 months earlier, and severe flexion contracture of the long finger and mild flexion contracture of the ring finger developed gradually. Diagnoses: localized type Volkmann's contracture. Intervention: Five months after the injury, transection of the FDP tendon to the long finger and transfer of the transected tendon to the FDP tendon to the index finger was performed after adjusting the tonus of these two tendons using a small skin incision. This procedure was followed by a tension-reduced early mobilization technique in which a tension-reduced position of the tendon suture site was maintained by taping the long finger to the volar side of the index finger, and then immediate active range of motion (ROM) exercise was started. Outcomes: Within 9 weeks after surgery, full ROM had been regained. Lessons: Using the treatment procedure presented in this case report, a good clinical result was obtained in a minimally invasive manner. PMID:28072735

  11. Copernicus observations of the N v resonance doublet in 53 early-type stars

    Science.gov (United States)

    Abbott, D. C.; Bohlin, R. C.; Savage, B. D.

    1982-01-01

    UV spectra in the wavelength interval 1170-1270 A are presented for 53 early-type stars ranging in spectral type from O6.5 V to B2.5 IV. The sample includes four Wolf-Rayet stars, seven known Oe-Be stars, and six galactic halo OB stars. A qualitative analysis of the stellar N v doublet reveals that: (1) N v is present in all stars hotter and more luminous than type B0 for the main sequence, B1 for giants, and B2 for supergiants; (2) shell components of N v and an unidentified absorption feature at 1230 A are present in about half of the stars; (3) the column density of N v is well correlated with bolometric luminosity over the spectral range O6 to B2; and (4) the ratio of emission to absorption equivalent width is a factor of 2 smaller in the main sequence stars than in supergiants, which suggests that the wind structure changes as a star evolves. For several stars, this ratio is too small to be explained by traditional wind models.

  12. Improving the surface-brightness color relation for early-type stars using optical interferometry

    CERN Document Server

    Challouf, M; Mourard, D; Graczyk, D; Aroui, H; Chesneau, O; Delaa, O; Pietrzyński, G; Gieren, W; Ligi, R; Meilland, A; Perraut, K; Tallon-Bosc, I; McAlister, H; Brummelaar, T ten; Sturmann, J; Sturmann, L; Turner, N; Farrington, C; Vargas, N; Scott, N

    2014-01-01

    The aim of this work is to improve the SBC relation for early-type stars in the $-1 \\leq V-K \\leq 0$ color domain, using optical interferometry. Observations of eight B- and A-type stars were secured with the VEGA/CHARA instrument in the visible. The derived uniform disc angular diameters were converted into limb darkened angular diameters and included in a larger sample of twenty four stars, already observed by interferometry, in order to derive a revised empirical relation for O, B, A spectral type stars with a V-K color index ranging from -1 to 0. We also take the opportunity to check the consistency of the SBC relation up to $V-K \\simeq 4$ using 100 additional measurements. We determined the uniform disc angular diameter for the eight following stars: $\\gamma$ Ori, $\\zeta$ Per, $8$ Cyg, $\\iota$ Her, $\\lambda$ Aql, $\\zeta$ Peg, $\\gamma$ Lyr and $\\delta$ Cyg with V-K color ranging from -0.70 to 0.02 and typical precision of about $1.5\\%$. Using our total sample of 132 stars with $V-K$ colors index ranging f...

  13. En face OCT angiography demonstrates flow in early type 3 neovascularization (retinal angiomatous proliferation)

    Science.gov (United States)

    Dansingani, K K; Naysan, J; Freund, K B

    2015-01-01

    Introduction The characteristics of type 3 neovascularization (NV), also known as retinal angiomatous proliferation, have been well described clinically, as well as with fluorescein angiography (FA), indocyanine green angiography, and optical coherence tomography (OCT). OCT angiography (OCT-A) is a novel and non-invasive technique for imaging retinal microvasculature by detecting changes, with respect to time, in reflectivity related to blood flow. Method In this case series, we describe two patients who presented with type 3 NV and underwent clinical examination and multimodal imaging, including OCT-A. Results In the first patient, OCT-A demonstrated flow within two separate lesions in the same eye, one of which was only weakly detected by FA. In the second patient, sequential OCT-A demonstrated a reduction in intralesional flow following intravitreal therapy. Conclusions OCT-A may have a role in the early diagnosis of type 3 NV and in assessing the response to treatment. Further studies are needed to determine sensitivity and specificity. PMID:25744441

  14. Gene expression profiling of reproductive meristem types in early rice inflorescences by laser microdissection.

    Science.gov (United States)

    Harrop, Thomas W R; Ud Din, Israr; Gregis, Veronica; Osnato, Michela; Jouannic, Stefan; Adam, Hélène; Kater, Martin M

    2016-04-01

    In rice, inflorescence architecture is established at early stages of reproductive development and contributes directly to grain yield potential. After induction of flowering, the complexity of branching, and therefore the number of seeds on the panicle, is determined by the activity of different meristem types and the timing of transitions between them. Although some of the genes involved in these transitions have been identified, an understanding of the network of transcriptional regulators controlling this process is lacking. To address this we used a precise laser microdissection and RNA-sequencing approach in Oryza sativa ssp. japonica cv. Nipponbare to produce quantitative data that describe the landscape of gene expression in four different meristem types: the rachis meristem, the primary branch meristem, the elongating primary branch meristem (including axillary meristems), and the spikelet meristem. A switch in expression profile between apical and axillary meristem types followed by more gradual changes during transitions in axillary meristem identity was observed, and several genes potentially involved in branching were identified. This resource will be vital for a mechanistic understanding of the link between inflorescence development and grain yield. © 2016 The Authors The Plant Journal © 2016 John Wiley & Sons Ltd.

  15. Kinematic Properties and Dark Matter Fraction of Virgo Dwarf Early-Type Galaxies

    CERN Document Server

    Toloba, E; Peletier, R; Gorgas, J

    2012-01-01

    What happens to dwarf galaxies as they enter the cluster potential well is one of the main unknowns in studies of galaxy evolution. Several evidence suggests that late-type galaxies enter the cluster and are transformed to dwarf early-type galaxies (dEs). We study the Virgo cluster to understand which mechanisms are involved in this transformation. We find that the dEs in the outer parts of Virgo have rotation curves with shapes and amplitudes similar to late-type galaxies of the same luminosity. These dEs are rotationally supported, have disky isophotes, and younger ages than those dEs in the center of Virgo, which are pressure supported, often have boxy isophotes and are older. Ram pressure stripping, thus, explains the properties of the dEs located in the outskirts of Virgo. However, the dEs in the central cluster regions, which have lost their angular momentum, must have suffered a more violent transformation. A combination of ram pressure stripping and harassment is not enough to remove the rotation and ...

  16. How similar is the stellar structure of low-mass late-type galaxies to that of early-type dwarfs?

    CERN Document Server

    Janz, Joachim; Laine, Jarkko; Salo, Heikki; Lisker, Thorsten

    2016-01-01

    We analyse structural decompositions of 500 late-type galaxies (Hubble $T$-type $\\ge 6$) from the Spitzer Survey of Stellar Structure in Galaxies (S$^4$G), spanning a stellar mass range of about $10^7$ to a few times $10^{10}$ M$_\\odot$. Their decomposition parameters are compared with those of the early-type dwarfs in the Virgo cluster from Janz et al. They have morphological similarities, including the fact that the fraction of simple one-component galaxies in both samples increases towards lower galaxy masses. We find that in the late-type two-component galaxies both the inner and outer structures are by a factor of two larger than those in the early-type dwarfs, for the same stellar mass of the component. While dividing the late-type galaxies to low and high density environmental bins, it is noticeable that both the inner and outer components of late types in the high local galaxy density bin are smaller, and lie closer in size to those of the early-type dwarfs. This suggests that, although structural dif...

  17. Exercise as a provocative test in early renal disease in type 1 (insulin-dependent) diabetes

    DEFF Research Database (Denmark)

    Feldt-Rasmussen, B; Baker, L; Deckert, T

    1985-01-01

    The value of exercise as a provocative test for early renal disease in Type 1 (insulin-dependent) diabetes was re-evaluated. Three carefully characterized groups of males were studied: 10 non-diabetic controls, 16 diabetic patients (group 1) with normal urinary albumin excretion (less than 15.......05). During exercise the urinary albumin excretion rate increased significantly in all three groups (normal subjects: 6 +/- 0.7 to 8 +/- 1.3 (microgram/min); group 1: 6 +/- 0.6 to 9 +/- 1 microgram/min and group 2: 48 +/- 10 to 113 +/- 23 micrograms/min), the relative increase being higher in group 2 (p less...... micrograms/min) and 14 Albustix-negative diabetics (group 2) with increased urinary albumin excretion (15-122 micrograms/min). Assignment to a study group was made on the basis of three 24-h urine collections, and the groups were well matched for age, weight, height, and serum creatinine concentration...

  18. The fundamental plane of early-type galaxies in different environments

    Directory of Open Access Journals (Sweden)

    R.M. Samir

    2016-12-01

    Full Text Available The study of Early-Type Galaxies (ETGs in different environments is a strong tool to understand their star formation history and their evolution. The Fundamental Plane (FP of ETGs has been studied in different environments in the nearby universe such as in groups, clusters and the field. We found that our sample of ETGs in different environments shows a good agreement with the FP of Coma cluster, except for a scatter of some galaxies. A major part of the scatter in the FP is due to variations in mass to light ratio as a result of metallicity or age trends in the stellar populations and structural or dynamical properties of galaxies. We noticed that the most deviant galaxies from the FP show many fine structures as tidal tails, shells, dust and a kinematically distinct core which indicates a past merger involving at least one gas-rich progenitor.

  19. Central dark matter trends in early-type galaxies from strong lensing, dynamics and stellar populations

    CERN Document Server

    Tortora, C; Romanowsky, A J; Jetzer, Ph

    2010-01-01

    We analyze the correlations between central dark matter (DM) content of early-type galaxies and their sizes and ages, using a sample of intermediate-redshift (z ~ 0.2) gravitational lenses from the SLACS survey, and by comparing them to a larger sample of z ~ 0 galaxies. We decompose the deprojected galaxy masses into DM and stellar components using combinations of strong lensing, stellar dynamics, and stellar populations modeling. For a given stellar mass, we find that for galaxies with larger sizes, the DM fraction increases and the mean DM density decreases, consistently with the cuspy halos expected in cosmological formation scenarios. The DM fraction also decreases with stellar age, which can be partially explained by the inverse correlation between size and age. The residual trend may point to systematic dependencies on formation epoch of halo contraction or stellar initial mass functions. These results are in agreement with recent findings based on local galaxies by Napolitano, Romanowsky & Tortora...

  20. The early-type strong emission-line supergiants of the Magellanic Clouds - A spectroscopic zoology

    Science.gov (United States)

    Shore, S. N.; Sanduleak, N.

    1984-01-01

    The results of a spectroscopic survey of 21 early-type extreme emission line supergiants of the Large and Small Magellanic Clouds using IUE and optical spectra are presented. The combined observations are discussed and the literature on each star in the sample is summarized. The classification procedures and the methods by which effective temperatures, bolometric magnitudes, and reddenings were assigned are discussed. The derived reddening values are given along with some results concerning anomalous reddening among the sample stars. The derived mass, luminosity, and radius for each star are presented, and the ultraviolet emission lines are described. Mass-loss rates are derived and discussed, and the implications of these observations for the evolution of the most massive stars in the Local Group are addressed.

  1. Supermassive blackhole growth and the supernovae history in high-z early-type galaxies

    Science.gov (United States)

    Rocca-Volmerange, Brigitte

    2015-08-01

    A large variety of feedback models, supported by many galaxy surveys, tentatively relate AGN to star formation by stimulation or quenching. However any accretion process from variable AGNs has never been observed to be turned on or off by star formation. We propose to follow the supernovae explosions through the star formation laws of early-type galaxies with the help of the galaxy evolution model Pégase.3. Applied to the continuous Spectral Energy Distribution, including Herschel data of two z=3.8 radio galaxies (4C41.17 and TN J2007-1316), the comparison with Supermassive BlackHole masses from SDSS opens a new interpretation of the AGN-starburst relation without any need of feedback (Rocca-Volmerange et al, 2015, 2013)

  2. New type IV pili-related genes involved in early stages of Ralstonia solanacearum potato infection.

    Science.gov (United States)

    Siri, María Inés; Sanabria, Analía; Boucher, Christian; Pianzzola, María Julia

    2014-07-01

    This study provides insights into the pathogenesis of Ralstonia solanacearum, in particular with regards to strains belonging to phylotype IIB, sequevar 1 (IIB-1) and their interaction with potato, its natural host. We performed a comparative genomic analysis among IIB-1 R. solanacearum strains with different levels of virulence in order to identify candidate virulence genes. With this approach, we identified a 33.7-kb deletion in a strain showing reduced virulence on potato. This region contains a cluster of six genes putatively involved in type IV pili (Tfp) biogenesis. Functional analysis suggests that these proteins contribute to several Tfp-related functions such as twitching motility and biofilm formation. In addition, this genetic cluster was found to contribute to early bacterial wilt pathogenesis and colonization fitness of potato roots.

  3. The Fundamental Plane of Early-Type Galaxies as a Confounding Correlation

    CERN Document Server

    Fraix-Burnet, Didier

    2011-01-01

    Early-type galaxies are characterized by many scaling relations. One of them, the so-called fundamental plane is a relatively tight correlation between three variables, and has resisted a clear physical understanding despite many years of intensive research. Here, we show that the correlation between the three variables of the fundamental plane can be the artifact of the effect of another parameter influencing all, so that the fundamental plane may be understood as a confounding correlation. Indeed, the complexity of the physics of galaxies and of their evolution suggests that the main confounding parameter must be related to the level of diversification reached by the galaxies. Consequently, many scaling relations for galaxies are probably evolutionary correlations.

  4. Modelling multi-wavelength observational characteristics of bow shocks from runaway early type stars

    CERN Document Server

    Acreman, David M; Harries, Tim J

    2015-01-01

    We assess the multi-wavelength observable properties of the bow shock around a runaway early type star using a combination of hydrodynamical modelling, radiative transfer calculations and synthetic imaging. Instabilities associated with the forward shock produce dense knots of material which are warm, ionised and contain dust. These knots of material are responsible for the majority of emission at far infra-red, H alpha and radio wavelengths. The large scale bow shock morphology is very similar and differences are primarily due to variations in the assumed spatial resolution. However infra-red intensity slices (at 22 microns and 12 microns) show that the effects of a temperature gradient can be resolved at a realistic spatial resolution for an object at a distance of 1 kpc.

  5. New radio detections of early-type pre-main-sequence stars

    Science.gov (United States)

    Skinner, Stephen L.; Brown, Alexander; Linsky, Jeffrey L.

    1990-01-01

    Results of VLA radio continuum observations of 13 early-type pre-main-sequence stars selected from the 1984 catalog of Finkenzeller and Mundt are presented. The stars HD 259431 and MWC 1080 were detected at 3.6 cm, while HD 200775 and TY CrA were detected at both 3.6 and 6 cm. The flux density of HD 200775 has a frequency dependence consistent with the behavior expected for free-free emission originating in a fully ionized wind. However, an observation in A configuration suggests that the source geometry may not be spherically symmetric. In contrast, the spectral index of TY CrA is negative with a flux behavior implying nonthermal emission. The physical mechanism responsible for the nonthermal emission has not yet been identified, although gyrosynchrotron and synchrotron processes cannot be ruled out.

  6. Size Evolution of Early-Type Galaxies and Massive Compact Objects as the Dark Matter

    CERN Document Server

    Totani, Tomonori

    2009-01-01

    The dramatic size evolution of early-type galaxies from z ~ 2 to 0 poses a new challenge in the theory of galaxy formation, which may not be explained by the standard picture. It is shown here that the size evolution can be explained if the non-baryonic cold dark matter is composed of compact objects having a mass scale of ~10^5 M_sun. This form of dark matter is consistent with or only weakly constrained by the currently available observations. The kinetic energy of the dark compact objects is transferred to stars by dynamical friction, and stars around the effective radius are pushed out to larger radii, resulting in a pure size evolution. This scenario has several good properties to explain the observations, including the ubiquitous nature of size evolution and faster disappearance of higher density galaxies.

  7. Modeling the Ages and Metallicities of Early-Type Galaxies in Fundamental Plane Space

    CERN Document Server

    Porter, L A; Primack, J R; Croton, D J; Covington, M D; Graves, G J; Faber, S M

    2014-01-01

    Recent observations have probed the formation histories of nearby elliptical galaxies by tracking correlations between the stellar population parameters, age and metallicity, and the structural parameters that enter the Fundamental Plane, radius and velocity dispersion sigma. These studies have found intriguing correlations between these four parameters. In this work, we make use of a semi-analytic model, based on halo merger trees extracted from the Bolshoi cosmological simulation, that predicts the structural properties of spheroid-dominated galaxies based on an analytic model that has been tested and calibrated against an extensive suite of hydrodynamic+N-body binary merger simulations. We predict the radius, sigma, luminosity, age, and metallicity of spheroid-dominated galaxies, enabling us to compare directly to observations. Our model predicts a strong correlation between age and sigma for early-type galaxies, and no significant correlation between age and radius, in agreement with observations. In addi...

  8. The Total Mass of the Early-Type Galaxy NGC 4649 (M60

    Directory of Open Access Journals (Sweden)

    Ćirković, M. M.

    2008-12-01

    Full Text Available In this paper the problem of the total mass and the total mass-to-light ratio of the early-type galaxy NGC~4649 (M60 is analyzed. Use is made of two independent techniques: the X-ray methodology which is based on the temperature of the X-ray halo of NGC~4649 and the tracer mass estimator (TME which uses globular clusters (GCs observed in this galaxy. The mass is calculated in Newtonian and MOdified Newtonian Dynamics (MOND approaches and it is found that inside 3 effective radii ($R_e$ there is no need for large amounts of dark matter. Beyond $3R_e$ the dark matter starts to play important dynamical role. The possible reasons for the discrepancy between the estimates of the total mass based on X-rays and TME in the outer regions of NGC~4649 are also discussed.

  9. Suppression of star formation in early-type galaxies by feedback from supermassive black holes.

    Science.gov (United States)

    Schawinski, Kevin; Khochfar, Sadegh; Kaviraj, Sugata; Yi, Sukyoung K; Boselli, Alessandro; Barlow, Tom; Conrow, Tim; Forster, Karl; Friedman, Peter G; Martin, D Chris; Morrissey, Patrick; Neff, Susan; Schiminovich, David; Seibert, Mark; Small, Todd; Wyder, Ted K; Bianchi, Luciana; Donas, Jose; Heckman, Tim; Lee, Young-Wook; Madore, Barry; Milliard, Bruno; Rich, R Michael; Szalay, Alex

    2006-08-24

    Detailed high-resolution observations of the innermost regions of nearby galaxies have revealed the presence of supermassive black holes. These black holes may interact with their host galaxies by means of 'feedback' in the form of energy and material jets; this feedback affects the evolution of the host and gives rise to observed relations between the black hole and the host. Here we report observations of the ultraviolet emissions of massive early-type galaxies. We derive an empirical relation for a critical black-hole mass (as a function of velocity dispersion) above which the outflows from these black holes suppress star formation in their hosts by heating and expelling all available cold gas. Supermassive black holes are negligible in mass compared to their hosts but nevertheless seem to play a critical role in the star formation history of galaxies.

  10. Low dark matter content of the nearby early-type galaxy NGC 821

    Directory of Open Access Journals (Sweden)

    Samurović S.

    2014-01-01

    Full Text Available In this paper we analyze the kinematics and dynamics of the nearby early-type galaxy NGC 821 based on its globular clusters (GCs and planetary nebulae (PNe. We use PNe and GCs to extract the kinematics of NGC 821 which is then used for the dynamical modelling based on the Jeans equation. We apply the Jeans equation using the Newtonian mass-follows-light approach assuming constant mass-to-light ratio and find that using such an approach we can successfully fit the kinematic data. The inferred constant mass-to-light ratio, 4:2 < M=LB < 12:4 present throughout the whole galaxy, implies the lack of significant amount of dark matter. We also used three different MOND approaches and found that we can fit the kinematic data without the need for additional, dark, component. [Projekat Ministarstva nauke Republike Srbije, br. 176021: Visible and invisible matter in nearby galaxies: theory and observations

  11. The impact of mechanical AGN feedback on the formation of massive early-type galaxies

    CERN Document Server

    Choi, Ena; Naab, Thorsten; Oser, Ludwig; Moster, Benjamin P

    2014-01-01

    We employ cosmological hydrodynamical simulations to investigate the effects of AGN feedback on the formation of massive galaxies with present-day stellar masses of $M_{stel} > 8.9 \\times 10^{10} M_{sun}$. Using smoothed particle hydrodynamics simulations with a pressure-entropy formulation that allows an improved treatment of contact discontinuities and fluid mixing, we run three sets of simulations of 20 halos with different AGN feedback models: (1) no feedback, (2) thermal feedback, and (3) mechanical and radiation feedback. We assume that seed black holes are present at early cosmic epochs at the centre of emerging dark matter halos and trace their mass growth via gas accretion and mergers with other black holes. Both feedback models successfully recover the observed M_BH - sigma relation and black hole-to-stellar mass ratio for simulated central early-type galaxies. The baryonic conversion efficiencies are reduced by a factor of two compared to models without any AGN feedback at all halo masses. However,...

  12. Graph-based pancreatic islet segmentation for early type 2 diabetes mellitus on histopathological tissue.

    Science.gov (United States)

    Floros, Xenofon; Fuchs, Thomas J; Rechsteiner, Markus P; Spinas, Giatgen; Moch, Holger; Buhmann, Joachim M

    2009-01-01

    It is estimated that in 2010 more than 220 million people will be affected by type 2 diabetes mellitus (T2DM). Early evidence indicates that specific markers for alpha and beta cells in pancreatic islets of Langerhans can be used for early T2DM diagnosis. Currently, the analysis of such histological tissues is manually performed by trained pathologists using a light microscope. To objectify classification results and to reduce the processing time of histological tissues, an automated computational pathology framework for segmentation of pancreatic islets from histopathological fluorescence images is proposed. Due to high variability in the staining intensities for alpha and beta cells, classical medical imaging approaches fail in this scenario. The main contribution of this paper consists of a novel graph-based segmentation approach based on cell nuclei detection with randomized tree ensembles. The algorithm is trained via a cross validation scheme on a ground truth set of islet images manually segmented by 4 expert pathologists. Test errors obtained from the cross validation procedure demonstrate that the graph-based computational pathology analysis proposed is performing competitively to the expert pathologists while outperforming a baseline morphological approach.

  13. The early phases of the type Iax supernova SN 2011ay

    CERN Document Server

    Szalai, Tamás; Sárneczky, Krisztián; Takáts, Katalin; Benkő, József M; Kelemen, János; Kuli, Zoltán; Silverman, Jeffrey M; Marion, G Howie; Wheeler, J Craig

    2015-01-01

    We present a detailed study of the early phases of the peculiar supernova 2011ay based on BVRI photometry obtained at Konkoly Observatory, Hungary, and optical spectra taken with the Hobby-Eberly Telescope at McDonald Observatory, Texas. The spectral analysis carried out with SYN++ and SYNAPPS confirms that SN 2011ay belongs to the recently defined class of SNe Iax, which is also supported by the properties of its light and color curves. The estimated photospheric temperature around maximum light, T_{phot} ~8,000 K, is lower than in most Type Ia SNe, which results in the appearance of strong Fe II features in the spectra of SN 2011ay, even during the early phases. We also show that strong blending with metal features (those of Ti II, Fe II, Co II) makes the direct analysis of the broad spectral features very difficult, and this may be true for all SNe Iax. We find two alternative spectrum models that both describe the observed spectra adequately, but their photospheric velocities differ by at least 3,000 km/s...

  14. Early intracardiac thrombosis in preterm infants and thrombolysis with recombinant tissue type plasminogen activator

    Science.gov (United States)

    Ferrari, F; Vagnarelli, F; Gargano, G; Roversi, M; Biagioni, O; Ranzi, A; Cavazzuti, G

    2001-01-01

    OBJECTIVES—To determine the incidence of catheter related thrombosis and to test the efficacy of recombinant tissue type plasminogen activator (rt-PA) in preterm infants.
STUDY DESIGN—From January 1995 to December 1998, echocardiography was performed in the first few days of life in 76 very low birthweight (⩽ 1500 g) infants out of a total of 147 having an umbilical catheter placed. When intracardiac thrombosis was diagnosed, rt-PA infusion was performed.
RESULTS—Four infants (5%) developed an intracardiac thrombosis during the first few days of life. In three of them, rt-PA at a dose of 0.4-0.5 mg/kg in a 20-30 minute bolus led to dissolution of the clot. One patient received a three hour infusion after the bolus, at a dose of 0.1 mg/kg/h, with resolution of the thrombus. No systemic effects were observed after rt-PA infusion.
CONCLUSIONS—Early thrombosis may occur as a complication of umbilical catheterisation in preterm infants; early echocardiographic detection of this disorder allows complete, safe, and rapid lysis with rt-PA.

 PMID:11420328

  15. Early-onset Alzheimer’s Disease: Nonamnestic Subtypes and Type 2 AD

    Science.gov (United States)

    Mendez, Mario F.

    2012-01-01

    Patients with Alzheimer’s disease (AD), the most prevalent neurodegenerative dementia, are usually elderly; however, ~4–5% develop early-onset AD (EOAD) with onset before age 65. Most EOAD is sporadic, but about 5% of patients with EOAD have an autosomal dominant mutation such as Presenilin 1, Presenilin 2, or alterations in the Amyloid Precursor Protein gene. Although most Alzheimer’s research has concentrated on older, late-onset AD (LOAD), there is much recent interest and research in EOAD. These recent studies indicate that EOAD is a heterogeneous disorder with significant differences from LOAD. From 22–64% of EOAD patients have a predominant nonamnestic syndrome presenting with deficits in language, visuospatial abilities, praxis, or other non-memory cognition. These nonamnestic patients may differ in several ways from the usual memory or amnestic patients. Patients with nonamnestic EOAD compared to typical amnestic AD have a more aggressive course, lack the apolipoprotein E ε4 (APOE ε4) susceptibility gene for AD, and have a focus and early involvement of non-hippocampal areas of brain, particularly parietal neocortex. These differences in the EOAD subtypes indicate differences in the underlying amyloid cascade, the prevailing pathophysiological theory for the development of AD. Together the results of recent studies suggest that nonamnestic subtypes of EOAD constitute a Type 2 AD distinct from the usual, typical disorder. In sum, the study of EOAD can reveal much about the clinical heterogeneity, predisposing factors, and neurobiology of this disease. PMID:23178565

  16. Renal sonographic findings of type I glycogen storage disease in infancy and early childhood

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Chun-Chen; Lin, Shuan-Pei [Mackay Memorial Hospital, Department of Pediatrics, Taipei (Taiwan); Tsai, Jeng-Daw; Lee, Hung-Chang [Mackay Memorial Hospital, Department of Pediatrics, Taipei (Taiwan); Taipei Medical University, Department of Pediatrics, Taipei (Taiwan)

    2005-08-01

    Type I glycogen storage disease (GSD-I) is an inherited disorder affecting glycogenolysis and gluconeogenesis. The characteristic manifestations are hepatomegaly, hypoglycemia, hyperlacticacidemia, hyperuricemia, and hyperlipidemia. Renal disease is regarded as a long-term complication and is reported mainly in older patients. We report the renal manifestations and renal ultrasonographic findings of GSD-I in infancy and early childhood in order to assess the role of renal sonography in the diagnosis of GSD-I. We retrospectively reviewed our hospital's database for patients with GSD-I from January 1993 to September 2004. The records of five patients were reviewed for this study. These five patients were diagnosed when they were younger than 3 years old. Data extracted from the charts included the initial extrarenal and renal manifestations, laboratory data, and imaging studies. We analyzed the indications for, and results of, renal sonography. In addition to the clinical presentations and laboratory abnormalities, all five children had nephromegaly and increased echogenicity on ultrasonography on their first visit, although only a minor degree of tubular dysfunction was noted clinically. Three of these five patients had nephrocalcinosis or renal stones or both. Hyperechoic large kidneys, nephrocalcinosis, and renal stones are common in GSD-I. They can be present in early infancy. Abnormalities on renal sonography might suggest GSD-I in a patient with suspected inborn errors of metabolism. (orig.)

  17. The SLUGGS survey: the assembly histories of individual early-type galaxies

    Science.gov (United States)

    Forbes, Duncan A.; Romanowsky, Aaron J.; Pastorello, Nicola; Foster, Caroline; Brodie, Jean P.; Strader, Jay; Usher, Christopher; Pota, Vincenzo

    2016-04-01

    Early-type (E and S0) galaxies may have assembled via a variety of different evolutionary pathways. Here, we investigate these pathways by comparing the stellar kinematic properties of 24 early-type galaxies from the SAGES Legacy Unifying Globulars and GalaxieS (SLUGGS) survey with the hydrodynamical simulations of Naab et al. In particular, we use the kinematics of starlight up to 4 effective radii (Re) as diagnostics of galaxy inner and outer regions, and assign each galaxy to one of six Naab et al. assembly classes. The majority of our galaxies (14/24) have kinematic characteristics that indicate an assembly history dominated by gradual gas dissipation and accretion of many gas-rich minor mergers. Three galaxies, all S0s, indicate that they have experienced gas-rich major mergers in their more recent past. One additional elliptical galaxy is tentatively associated with a gas-rich merger which results in a remnant galaxy with low angular momentum. Pathways dominated by gas-poor (major or minor) mergers dominate the mass growth of six galaxies. Most SLUGGS galaxies appear to have grown in mass (and size) via the accretion of stars and gas from minor mergers, with late major mergers playing a much smaller role. We find that the fraction of accreted stars correlates with the stellar mean age and metallicity gradient, but not with the slope of the total mass density profile. We briefly mention future observational and modelling approaches that will enhance our ability to accurately reconstruct the assembly histories of individual present-day galaxies.

  18. Early-type Galaxies in the Cluster Abell 2390 at z=0.23

    Science.gov (United States)

    Fritz, A.; Ziegler, B. L.

    2003-07-01

    A key question of early-type galaxy evolution is when and within what timescales their stellar populations have been formed. In monolithic collapse models a burst of star formation at high redshift (zform>=2) is followed by a passive evolution of the stellar populations, whereas in the hierachical galaxy formation scenario the assembly timescales for more massive galaxies are longer, resulting in somewhat younger mean ages. To investigate the environmental dependence of this question we obtained high-quality spectra of 51 elliptical and lenticular galaxies in the rich cluster A2390 at z=0.23 with MOSCA at the 3.5-m telescope on Calar Alto Observatory. Our investigation spans a wider range in luminosity (M*B+1) than previous spectroscopic studies at intermediate redshift, which were limited to a small number of the more luminous galaxies (apart from the study of Ziegler et al. 2001 MNRAS, 325, 1571 of the cluster A2218 at z=0.18). The evolution of galaxies in age, metallicity and abundance ratios is explored by analysing absorption line strengths, such as H&beta, Mgb, Fe5270 and Fe5335, in comparison with stellar population models. Velocity dispersions (&sigma) are determined to study the slope, scatter and zeropoint of the Faber-Jackson and Mg-&sigma relations. For a subsample of 14 galaxies where morphological and structural parameters are available from HST observations, we also investigate the evolution of the Fundamental Plane. With our large sample it is possible to look for variations in early-type galaxy evolution as a function of distance from the cluster center as well as for different sub-populations like S0 or Balmer-line enhanced galaxies in a statistically significant way.

  19. Early limited nitrosamine exposures exacerbate high fat diet-mediated type 2 diabetes and neurodegeneration

    Directory of Open Access Journals (Sweden)

    Longato Lisa

    2010-03-01

    Full Text Available Abstract Background Type 2 diabetes mellitus (T2DM and several types of neurodegeneration, including Alzheimer's, are linked to insulin-resistance, and chronic high dietary fat intake causes T2DM with mild neurodegeneration. Intra-cerebral Streptozotocin, a nitrosamine-related compound, causes neurodegeneration, whereas peripheral treatment causes DM. Hypothesis Limited early exposures to nitrosamines that are widely present in the environment, enhance the deleterious effects of high fat intake in promoting T2DM and neurodegeneration. Methods Long Evans rat pups were treated with N-nitrosodiethylamine (NDEA by i.p. injection, and upon weaning, they were fed with high fat (60%; HFD or low fat (5%; LFD chow for 8 weeks. Cerebella were harvested to assess gene expression, and insulin and insulin-like growth factor (IGF deficiency and resistance in the context of neurodegeneration. Results HFD ± NDEA caused T2DM, neurodegeneration with impairments in brain insulin, insulin receptor, IGF-2 receptor, or insulin receptor substrate gene expression, and reduced expression of tau and choline acetyltransferase (ChAT, which are regulated by insulin and IGF-1. In addition, increased levels of 4-hydroxynonenal and nitrotyrosine were measured in cerebella of HFD ± NDEA treated rats, and overall, NDEA+HFD treatment reduced brain levels of Tau, phospho-GSK-3β (reflecting increased GSK-3β activity, glial fibrillary acidic protein, and ChAT to greater degrees than either treatment alone. Finally, pro-ceramide genes, examined because ceramides cause insulin resistance, oxidative stress, and neurodegeneration, were significantly up-regulated by HFD and/or NDEA exposure, but the highest levels were generally present in brains of HFD+NDEA treated rats. Conclusions Early limited exposure to nitrosamines exacerbates the adverse effects of later chronic high dietary fat intake in promoting T2DM and neurodegeneration. The mechanism involves increased generation of

  20. Early progression of the autonomic dysfunction observed in pediatric type 1 diabetes mellitus.

    Science.gov (United States)

    Lucini, Daniela; Zuccotti, Gianvincenzo; Malacarne, Mara; Scaramuzza, Andrea; Riboni, Sara; Palombo, Carlo; Pagani, Massimo

    2009-11-01

    To focus on early cardiac and vascular autonomic dysfunction that might complicate type 1 diabetes mellitus in children, we planned an observational, cross-sectional study in a population of 93 young patients, under insulin treatment, subdivided in 2 age subgroups (children: 11.5+/-0.4 years; adolescents: 19.3+/-0.2 years). Time and frequency domain analysis of RR interval and systolic arterial pressure variability provided quantitative indices of the sympatho-vagal balance regulating the heart period, of the gain of cardiac baroreflex, and of the sympathetic vasomotor control. Sixty-eight children of comparable age served as a reference group. At rest, systolic arterial pressure and the power of its low-frequency component were greater in patients than in controls, particularly in children (14.0+/-2.3 versus 3.1+/-0.3 mm Hg2). Moreover, baroreflex gain was significantly reduced in both subgroups of patients. Standing induced similar changes in the autonomic profiles of controls and patients. A repeat study after 1 year showed a progression in low-frequency oscillations of arterial pressure and a shift toward low frequency in RR variability. Data in young patients with type 1 diabetes mellitus show a significant increase in arterial pressure, a reduced gain of the baroreflex regulation of the heart period, and an increase of the low-frequency component of systolic arterial pressure variability, suggestive of simultaneous impairment of vagal cardiac control and increases of sympathetic vasomotor regulation. A repeat study after 1 year shows a further increase of sympathetic cardiac and vascular modulation, suggesting early progression of the autonomic dysfunction.

  1. Factors Associated With Disability and Sick Leave in Early Complex Regional Pain Syndrome Type-1.

    Science.gov (United States)

    Bean, Debbie J; Johnson, Malcolm H; Heiss-Dunlop, Wolfgang; Kydd, Robert R

    2016-02-01

    Factors influencing disability and work absence in complex regional pain syndrome type-1 (CRPS)-1 have not been thoroughly described in the literature. We sought to determine whether demographic variables, work-related factors, CRPS clinical severity ratings, pain scores, or psychological variables were associated with disability and sick leave in early CRPS-1. A total of 66 CRPS-1 patients were recruited within 12 weeks of CRPS onset. Patients completed measures of pain, depression, anxiety, stress, pain catastrophizing, and pain-related fear. A physical examination was conducted to assess signs and symptoms of CRPS and to calculate a CRPS severity score. Demographic details, clinical details, treatments, work type, and work status were recorded. In multivariate analyses, the following factors were associated with greater disability: higher pain scores, more restricted ankle or wrist extension, and higher levels of depression. Among the 49 who were either working or studying before developing CRPS, 28 had stopped work or study at the time of assessment. Multivariate analyses showed that sick leave was more likely among those whose CRPS was triggered by more severe injuries, whose work was more physically demanding, among those with higher disability scores, and there was also a significant effect of depression on sick leave, which was mediated by disability. Although the study was cross-sectional and so cannot differentiate cause from effect, results suggest that even in the early stages of CRPS, a cycle of pain, disability, depression, and work absence can emerge. Treatments aimed to prevent this cycle may help prevent adverse long-term outcomes.

  2. Reduced β-cell function in early preclinical type 1 diabetes

    Science.gov (United States)

    Koskinen, Maarit K; Helminen, Olli; Matomäki, Jaakko; Aspholm, Susanna; Mykkänen, Juha; Mäkinen, Marjaana; Simell, Ville; Vähä-Mäkilä, Mari; Simell, Tuula; Ilonen, Jorma; Knip, Mikael; Veijola, Riitta; Toppari, Jorma; Simell, Olli

    2016-01-01

    Objective We aimed to characterize insulin responses to i.v. glucose during the preclinical period of type 1 diabetes starting from the emergence of islet autoimmunity. Design and methods A large population-based cohort of children with HLA-conferred susceptibility to type 1 diabetes was observed from birth. During regular follow-up visits islet autoantibodies were analysed. We compared markers of glucose metabolism in sequential intravenous glucose tolerance tests between 210 children who were positive for multiple (≥2) islet autoantibodies and progressed to type 1 diabetes (progressors) and 192 children testing positive for classical islet-cell antibodies only and remained healthy (non-progressors). Results In the progressors, the first phase insulin response (FPIR) was decreased as early as 4–6 years before the diagnosis when compared to the non-progressors (P=0.001). The difference in FPIR between the progressors and non-progressors was significant (P<0.001) in all age groups, increasing with age (at 2 years: difference 50% (95% CI 28–75%) and at 10 years: difference 172% (95% CI 128–224%)). The area under the 10-min insulin curve showed a similar difference between the groups (P<0.001; at 2 years: difference 36% (95% CI 17–58%) and at 10 years: difference 186% (95% CI 143–237%)). Insulin sensitivity did not differ between the groups. Conclusions FPIR is decreased several years before the diagnosis of type 1 diabetes, implying an intrinsic defect in β-cell mass and/or function. PMID:26620391

  3. CpG Type A Induction of an Early Protective Environment in Experimental Multiple Sclerosis

    Directory of Open Access Journals (Sweden)

    James Crooks

    2017-01-01

    Full Text Available Experimental autoimmune encephalomyelitis (EAE is an inflammatory, demyelinating disease of the CNS that mimics human multiple sclerosis (MS, and it is thought to be driven by Th1 and Th17 myelin-reactive cells. Although adaptive immunity is clearly pivotal in the pathogenesis of EAE, with an essential role of CD4+ T cells, little is known of early, innate responses in this experimental setting. CpG-rich oligodeoxynucleotides (ODNs, typically found in microbial genomes, are potent activators of TLR9 in plasmacytoid dendritic cells (pDCs. In this study, we compared the effects of two types of CpG, namely, type A and type B, on EAE. We found that treatment with CpG type A ODN (CpG-A, known to induce high amounts of IFN-α in pDCs, significantly reduced disease severity in EAE, relative to controls (12.63±1.86 versus 23.49±1.46, resp.; p=0.001. Treatment also delayed onset of neurological deficits and reduced spinal cord demyelination, while increasing the percentage of splenic regulatory (Foxp3+ CD4+ T cells. CpG-A likewise reduced the levels of IL-17 and IFN-γ in the CNS. Mechanistic insight into those events showed that CpG-A promoted a regulatory phenotype in pDCs. Moreover, adoptive transfer of pDCs isolated from CpG-A-treated mice inhibited CNS inflammation and induced disease remission in acute-phase EAE. Our data thus identify a link between TLR9 activation by specific ligands and the induction of tolerance via innate immunity mechanisms.

  4. Hepatocyte nuclear factor 1-alpha mutation in normal glucose-tolerant subjects and early-onset type 2 diabetic patients.

    Science.gov (United States)

    Lim, Dong Mee; Huh, Nam; Park, Keun Yong

    2008-12-01

    The prevalence of diabetes in Korea is reported to be approximately 10%, but cases of maturity-onset diabetes of the young (MODY) are rare in Korea. A diagnostic technique for autosomal dominant MODY is being actively sought. In this regard, we used a DNA chip to investigate the frequency of mutations of the MODY3 gene (hepatocyte nuclear factor-1alpha) in Korean patients with early-onset type 2 diabetes. The genomic DNA of 30 normal individuals [age, 24.9+/-8.6 years] and 25 patients with early-onset type 2 diabetes (age, 27+/-5.9 years) was extracted, and the MODY3 gene was amplified. The amplified DNA was hybridized onto a MODY3 chip, which has oligonucleotides of 15-25 bases, representing wild-type and mutant MODY3 sequences in both forward and reverse orientations, immobilized on its surface. Among the normal subjects, there was no mutation of MODY3. Among those with early-onset type 2 diabetes, there was one case of MODY3 mutation. Our results indicate that MODY3 mutations are not rare in Korean early-onset type 2 diabetes patients in Korea and suggest that MODY3 mutations in patients with early-onset type 2 diabetes need to be further evaluated.

  5. Trends in the Globular Cluster Luminosity Function of Early-Type Galaxies

    CERN Document Server

    Jordan, A; Côté, P; Ferrarese, L; Peng, E W; Blakeslee, J P; Mei, S; Villegas, D; Merritt, D; Tonry, J L; West, M J; Jordan, Andres; Laughlin, Dean E. Mc; Cote, Patrick; Ferrarese, Laura; Peng, Eric W.; Blakeslee, John P.; Mei, Simona; Villegas, Daniela; Merritt, David; Tonry, John L.; West, Michael J.

    2006-01-01

    We present results from a study of the globular cluster luminosity function (GCLF) in a sample of 89 early-type galaxies observed as part of the ACS Virgo Cluster Survey. Using a Gaussian parametrization of the GCLF, we find a highly significant correlation between the GCLF dispersion, sigma, and the galaxy luminosity, M_B, in the sense that the GC systems in fainter galaxies have narrower luminosity functions. The GCLF dispersions in the Milky Way and M31 are fully consistent with this trend, implying that the correlation between sigma and galaxy luminosity is more fundamental than older suggestions that GCLF shape is a function of galaxy Hubble type. We show that the sigma - M_B relation results from a bonafide narrowing of the distribution of (logarithmic) cluster masses in fainter galaxies. We further show that this behavior is mirrored by a steepening of the GC mass function for relatively high masses, M >~ 3 x 10^5 M_sun, a mass regime in which the shape of the GCLF is not strongly affected by dynamical...

  6. The ATLAS3D project - XVIII. CARMA CO imaging survey of early-type galaxies

    CERN Document Server

    Alatalo, Katherine; Bureau, Martin; Young, Lisa M; Blitz, Leo; Crocker, Alison F; Bayet, Estelle; Bois, Maxime; Bournaud, Frédéric; Cappellari, Michele; Davies, Roger L; de Zeeuw, P T; Duc, Pierre-Alain; Emsellem, Eric; Khochfar, Sadegh; Krajnovic, Davor; Kuntschner, Harald; Lablanche, Pierre-Yves; Morganti, Raffaella; McDermid, Richard M; Naab, Thorsten; Oosterloo, Tom; Sarzi, Marc; Scott, Nicholas; Serra, Paolo; Weijmans, Anne-Marie

    2012-01-01

    We present the Combined Array for Research in Millimeter Astronomy (CARMA) ATLAS3D molecular gas imaging survey, a systematic study of the distribution and kinematics of molecular gas in CO-rich early-type galaxies. Our full sample of 40 galaxies (30 newly mapped and 10 taken from the literature) is complete to a 12CO(1-0) integrated flux of 18.5 Jy km/s, and it represents the largest, best-studied sample of its type to date. A comparison of the CO distribution of each galaxy to the g-r color image (representing dust) shows that the molecular gas and dust distributions are in good agreement and trace the same underlying interstellar medium. The galaxies exhibit a variety of CO morphologies, including discs (50%), rings (15%), bars+rings (10%), spiral arms (5%), and mildly (12.5%) and strongly (7.5%) disrupted morphologies. There appear to be weak trends between galaxy mass and CO morphology, whereby the most massive galaxies in the sample tend to have molecular gas in a disc morphology. We derive a lower limi...

  7. Myocardial involvement during the early course of type 2 diabetes mellitus: usefulness of Myocardial Performance Index

    Directory of Open Access Journals (Sweden)

    Goldoni Matteo

    2008-06-01

    Full Text Available Abstract To evaluate whether myocardial performance index detects a subclinical impairment of left ventricular systolic and diastolic function in patients with early stage of type 2 diabetes, without coronary artery disease, with or without hypertension. Furthermore, to evaluate whether some echocardiographic parameters relate to the metabolic control. Fourty-five consecutive male patients (mean age 52.5 years with type 2 diabetes mellitus of recent onset (23 hypertensives and 22 normotensives and 22 age matched healthy controls males were analysed. All participants had normal exercise ECG. All subjects underwent standard and Doppler echocardiography for the assessment of the isovolumic Doppler time interval and Doppler-derived myocardial performance index. In all diabetic patients a glycated haemoglobin test was also performed. No differences were observed in blood pressure, heart rate, and conventional echocardiographic parameters comparing the 2 subgroups of diabetic patients and the controls. Myocardial performance index was significantly higher in diabetic patients independently of the hypertension occurrence, compared to the controls (0.49 and 0.49 diabetic normotensives and hypertensives respectively vs. 0.39, p

  8. Spiral-like star-forming patterns in CALIFA early-type galaxies

    CERN Document Server

    Gomes, J M; Vílchez, J M; Kehrig, C; Iglesias-Páramo, J; Breda, I; Lehnert, M D; Sánchez, S F; Ziegler, B; Reis, S N dos; Bland-Hawthorn, J; Galbany, L; Bomans, D J; Rosales-Ortega, F F; Walcher, C J; García-Benito, R; Márquez, I; del Olmo, A; Mollá, M; Marino, R A; Catalán-Torrecilla, C; Delgado, R M González; López-Sánchez, Á R

    2015-01-01

    Based on a combined analysis of SDSS imaging and CALIFA integral field spectroscopy data, we report on the detection of faint (24 < {\\mu}$_r$ mag/arcsec$^2$ < 26) star-forming spiral-arm-like features in the periphery of three nearby early-type galaxies (ETGs). These features are of considerable interest because they document the still ongoing inside-out growth of some local ETGs and may add valuable observational insight into the origin and evolution of spiral structure in triaxial stellar systems. A characteristic property of the nebular component in the studied ETGs, classified i+, is a two-radial-zone structure, with the inner zone that displays faint (EW(H\\alpha)$\\simeq$1{\\AA}) low-ionization nuclear emission-line region (LINER) properties, and the outer one (3{\\AA}type i+ ETGs with single-fiber s...

  9. Spectroscopic aperture biases in inside-out evolving early-type galaxies from CALIFA

    CERN Document Server

    Gomes, J M; Vílchez, J M; Kehrig, C; Iglesias-Páramo, J; Breda, I; Lehnert, M D; Sánchez, S F; Ziegler, B; Reis, S N dos; Bland-Hawthorn, J; Galbany, L; Bomans, D J; Rosales-Ortega, F F; Walcher, C J; García-Benito, R; Márquez, I; del Olmo, A; Mollá, M; Marino, R A; Catalán-Torrecilla, C; Delgado, R M González; López-Sánchez, Á R

    2015-01-01

    Integral field spectroscopy studies based on CALIFA data have recently revealed the presence of ongoing low-level star formation (SF) in the periphery of ~10% of local early-type galaxies (ETGs), witnessing a still ongoing inside-out galaxy growth process. A distinctive property of the nebular component in these ETGs, classified i+, is a two-radial-zone structure, with the inner zone displaying LINER emission with a H\\alpha equivalent width EW~1{\\AA}, and the outer one (3{\\AA}type i+ ETGs: At low redshift (<~0.45), SDSS spectroscopy is restricted to the inner (SF-devoid LINER) zone, thereby leading to their erroneous classification as "retired" galaxies (systems lacking SF and whose faint emission is powered by pAGB stars). Only at higher z's the SDSS ...

  10. Star Formation in Nearby Early-Type Galaxies: The Radio Continuum Perspective

    CERN Document Server

    Nyland, Kristina; Wrobel, Joan M; Davis, Timothy A; Bureau, Martin; Alatalo, Katherine; Morganti, Raffaella; Duc, Pierre-Alain; de Zeeuw, P T; McDermid, Richard M; Crocker, Alison F; Oosterloo, Tom

    2016-01-01

    We present a 1.4 GHz Karl G. Jansky Very Large Array (VLA) study of a sample of early-type galaxies (ETGs) from the volume- and magnitude-limited ATLAS-3D survey. The radio morphologies of these ETGs at a resolution of 5" are diverse and include sources that are compact on sub-kpc scales, resolved structures similar to those seen in star-forming spiral galaxies, and kpc-scale radio jets/lobes associated with active nuclei. We compare the 1.4 GHz, molecular gas, and infrared (IR) properties of these ETGs. The most CO-rich ATLAS-3D ETGs have radio luminosities consistent with extrapolations from H_2-mass-derived star formation rates from studies of late-type galaxies. These ETGs also follow the radio-IR correlation. However, ETGs with lower molecular gas masses tend to have less radio emission relative to their CO and IR emission compared to spirals. The fraction of galaxies in our sample with high IR-radio ratios is much higher than in previous studies, and cannot be explained by a systematic underestimation o...

  11. Soft band X/K luminosity ratios for gas-poor early-type galaxies

    CERN Document Server

    Bogdan, Akos

    2010-01-01

    We aim to place upper limits on the combined X-ray emission from the population of steady nuclear-burning white dwarfs in galaxies. In the framework of the single-degenerate scenario these systems are believed to be likely progenitors of Type Ia supernovae. From the Chandra archive, we selected normal early-type galaxies with the point source detection sensitivity better than 10^37 erg/s to minimize the contribution of unresolved low-mass X-ray binaries. The galaxies, contaminated by emission from ionized ISM, were identified based on the analysis of radial surface brightness profiles and energy spectra. The sample was complemented by the bulge of M31 and the data for the solar neighborhood. To cover a broad range of ages, we also included NGC3377 and NGC3585. Our final sample includes eight gas-poor galaxies for which we determine L_X/L_K ratios in the 0.3-0.7 keV energy band. In computing the L_X we included both unresolved emission and soft resolved sources with the color temperature of kT_bb <= 200 eV....

  12. WASP-26b: a 1-Jupiter-mass planet around an early-G-type star

    Science.gov (United States)

    Smalley, B.; Anderson, D. R.; Collier Cameron, A.; Gillon, M.; Hellier, C.; Lister, T. A.; Maxted, P. F. L.; Queloz, D.; Triaud, A. H. M. J.; West, R. G.; Bentley, S. J.; Enoch, B.; Pepe, F.; Pollacco, D. L.; Segransan, D.; Smith, A. M. S.; Southworth, J.; Udry, S.; Wheatley, P. J.; Wood, P. L.; Bento, J.

    2010-09-01

    We report the discovery of WASP-26b, a moderately over-sized Jupiter-mass exoplanet transiting its 11.3-mag early-G-type host star (1SWASP J001824.70-151602.3; TYC 5839-876-1) every 2.7566 days. A simultaneous fit to transit photometry and radial-velocity measurements yields a planetary mass of 1.02 ± 0.03 MJup and radius of 1.32 ± 0.08 RJup. The host star, WASP-26, has a mass of 1.12 ± 0.03 M⊙ and a radius of 1.34 ± 0.06 R⊙ and is in a visual double with a fainter K-type star. The two stars are at least a common-proper motion pair with a common distance of around 250 ± 15 pc and an age of 6 ± 2 Gy. RV and photometric data are only available in electronic form at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/520/A56

  13. Giant Molecular Clouds in the Early-Type Galaxy NGC4526

    CERN Document Server

    Utomo, Dyas; Davis, Timothy; Rosolowsky, Erik; Bureau, Martin; Cappellari, Michele; Sarzi, Marc

    2015-01-01

    We present a high spatial resolution ($\\approx 20$ pc) of $^{12}$CO($2-1$) observations of the lenticular galaxy NGC4526. We identify 103 resolved Giant Molecular Clouds (GMCs) and measure their properties: size $R$, velocity dispersion $\\sigma_v$, and luminosity $L$. This is the first GMC catalog of an early-type galaxy. We find that the GMC population in NGC4526 is gravitationally bound, with a virial parameter $\\alpha \\sim 1$. The mass distribution, $dN/dM \\propto M^{-2.39 \\pm 0.03}$, is steeper than that for GMCs in the inner Milky Way, but comparable to that found in some late-type galaxies. We find no size-linewidth correlation for the NGC4526 clouds, in contradiction to the expectation from Larson's relation. In general, the GMCs in NGC4526 are more luminous, denser, and have a higher velocity dispersion than equal size GMCs in the Milky Way and other galaxies in the Local Group. These may be due to higher interstellar radiation field than in the Milky Way disk and weaker external pressure than in the ...

  14. Chicken Embryos as a Potential New Model for Early Onset Type I Diabetes

    Directory of Open Access Journals (Sweden)

    Liheng Shi

    2014-01-01

    Full Text Available Diabetic retinopathy (DR is the leading cause of blindness among the American working population. The purpose of this study is to establish a new diabetic animal model using a cone-dominant avian species to address the distorted color vision and altered cone pathway responses in prediabetic and early diabetic patients. Chicken embryos were injected with either streptozotocin (STZ, high concentration of glucose (high-glucose, or vehicle at embryonic day 11. Cataracts occurred in varying degrees in both STZ- and high glucose-induced diabetic chick embryos at E18. Streptozotocin-diabetic chicken embryos had decreased levels of blood insulin, glucose transporter 4 (Glut4, and phosphorylated protein kinase B (pAKT. In STZ-injected E20 embryos, the ERG amplitudes of both a- and b-waves were significantly decreased, the implicit time of the a-wave was delayed, while that of the b-wave was significantly increased. Photoreceptors cultured from STZ-injected E18 embryos had a significant decrease in L-type voltage-gated calcium channel (L-VGCC currents, which was reflected in the decreased level of L-VGCCα1D subunit in the STZ-diabetic retinas. Through these independent lines of evidence, STZ-injection was able to induce pathological conditions in the chicken embryonic retina, and it is promising to use chickens as a potential new animal model for type I diabetes.

  15. The ALHAMBRA survey: reliable morphological catalogue of 22,051 early- and late-type galaxies

    CERN Document Server

    Pović, M; Aguerri, J A L; Márquez, I; Masegosa, J; Husillos, C; Molino, A; Cristóbal-Hornillos, D; Perea, J; Benítez, N; del Olmo, A; Jiménez-Teja, Y; Moles, M; Alfaro, E; Aparicio-Villegas, T; Ascaso, B; Broadhurst, T; Cabrera-Caño, J; Castander, F J; Cepa, J; Cerviño, M; Lorenzo, M Fernández; Fernández-Soto, A; Delgado, R M González; Infante, L; López-Sanjuan, C; Martínez, V J; Matute, I; Oteo, I; Pérez-García, A M; Prada, F; Quintana, J M

    2013-01-01

    ALHAMBRA is a photometric survey designed to trace the cosmic evolution and cosmic variance. It covers a large area of ~ 4 sq. deg in 8 fields, where 7 fields overlap with other surveys, allowing to have complementary data in other wavelengths. All observations were carried out in 20 continuous, medium band (30 nm width) optical and 3 near-infrared (JHK) bands, providing the precise measurements of photometric redshifts. In addition, morphological classification of galaxies is crucial for any kind of galaxy formation and cosmic evolution studies, providing the information about star formation histories, their environment and interactions, internal perturbations, etc. We present a morphological classification of > 40,000 galaxies in the ALHAMBRA survey. We associate to every galaxy a probability to be early-type using the automated Bayesian code galSVM. Despite of the spatial resolution of the ALHAMBRA images (~ 1 arcsec), for 22,051 galaxies we obtained the contamination by other type of less than 10%. Of tho...

  16. Breast cancer - Early detection with mammography. Crushed stone-like calcifications - The most frequent malignant type

    Energy Technology Data Exchange (ETDEWEB)

    Tabar, Laszlo [Univ. of Uppsala (Sweden). School of Medicine]|[Central Hospital, Falun (Sweden). Dept. of Mammography; Tot, Tibor [Univ. of Uppsala (Sweden). School of Medicine]|[Central Hospital, Falun (Sweden). Dept. of Pathology and Clinical Cytology; Dean, Peter B. [Turku Univ. (Finland). Dept. of Diagnostic Radiology

    2008-07-01

    A comprehensive guide for analyzing the most common malignant type calcifications on the mammogram Internationally renowned breast cancer imagers Laszlo Tabar and Peter B. Dean and the eminent breast pathologist Tibor Tot distill decades of clinical expertise in this new volume covering the most frequently occurring malignant type calcifications: the pleomorphic, crushed stone-like calcifications. The book presents a systematic approach to using mammographic features to distinguish different subtypes of breast diseases originating within the terminal ductal lobular unit (TDLU). More than 800 images demonstrate abnormal findings with superb clarity, providing a state-of-the-art visual reference for interpreting mammograms in the clinical setting. Features: - Concise descriptions of mammographic and MRI findings correlated with high-quality histopathologic images to provide a reliable guide for accurate diagnosis and differential diagnosis, as well as prognostic classification - Extensive coverage of all aspects of the benign differential diagnostic counterparts of pleomorphic calcifications, including fibrocystic change, fibroadenoma, and papilloma - Straightforward discussion of terminology based on a thorough analysis of subgross anatomy, 3D histologic features, and long-term disease outcomes - 3D viewing glasses enclosed in the book for perceiving specially marked images in their true 3D form This book is ideal for all breast imagers and breast pathologists, as well as for surgeons and oncologists specializing in breast diseases. For the radiologist, this book is an indispensable reference for harnessing the power of mammography to detect breast cancer at the earliest stages possible. About the Breast Cancer: Early Detection with Mammography series: This series grew out of the bestselling book Breast Cancer: The Art and Science of Early Detection with Mammography. Written by the same authors, this series is based on 30 years of experience with more than one

  17. Quantifying Star Formation in Early-Type Galaxies using Spatially-Resolved UV-Optical Photometry

    Science.gov (United States)

    Kaviraj, Sugata

    2013-01-01

    Our understanding of star formation in nearby early-type galaxies (ETGs) has evolved rapidly in recent years, due to new UV data from GALEX and HST. Contrary to the classical notion of them being old, passively-evolving systems, recent work has demonstrated widespread late-epoch star formation in ETGs, which builds ~20% of their stellar mass after 1, via minor mergers between ETGs and gas-rich dwarfs. While survey data from GALEX has indicated the average properties of star formation in the ETG population as a whole, I demonstrate how spatially-resolved UV studies can offer detailed insights into the star formation histories of individual galaxies, using an HST-WFC3 case study of NGC 4150. Using a pixel-by-pixel analysis in 5 WFC3 filters, spanning UV to i-band, reveals a central 0.9 Gyr old young stellar population, with a median metallicity of 0.5 solar, that contributes around 3% of the stellar mass and coincides spatially with a small, kinematically-decoupled core (indicating a recent minor merger). Assuming that the metallicity of the young stars traces the gas-phase metallicity of the satellite that fuels the star formation, we use the mass-metallicity relation to estimate the mass ratio of the merger to be ~1:20. An WFC3 study of globular clusters reveals a substantial population of young star clusters coincident with the central region of star formation and indicates that the bulk of the stellar mass in this galaxy probably formed 6-8 Gyrs in the past. This study demonstrates the utility of high-resolution imaging from future instruments such as the extremely large telescopes. (Based on Early Release Science observations by the WFC3 Scientific Oversight Committee. We are grateful to the Director of the Space Telescope Science Institute for awarding Director's Discretionary time for this program.)

  18. The Origin of Isolated Early-Type Galaxies: A Multiwavelength Study of Three Systems

    Science.gov (United States)

    Fanelli, Michael N.; Marcum, Pamela M.; Ashley, Trisha L.; Fuse, Christopher R.; O'Toole Appleby, Heather

    2017-01-01

    One major approach to understanding the zero-redshift galaxy population is to distinguish the processes driving passive (internal) evolution of stellar systems from interaction-induced changes. The study of the structure and star formation history of highly isolated systems defines the baseline for quiescent evolution. Isolated early-type galaxies (ETGs) are an especially interesting population, since most ETGs are found in cluster environments. Possible evolutionary paths for isolated ETGs are merged (formerly) compact groups or direct collapse early in cosmic time.As part of our long-term program to identify and explore highly isolated ETGs, we present panchromatic observations of the stars, neutral gas and dust in three highly isolated systems: Mrk 150, KIG 824 and SDSS J235021+141343, a subset of our initial isolated ETG sample. Our goal is to understand the evolutionary paths for these systems, in terms of their merger history, gas fueling and star formation rates. Each system presents diverse properties: Mrk 150 is optically blue and currently forming stars, while KIG 824 is red with no evidence for ongoing star formation; all possess neutral gas. Mrk 150 fits the class of luminous blue compact galaxies [M(V) = -19.2, B-V = 0.47] and possibly represents a link in the evolutionary chain leading to isolated, red and dead systems.We combine GALEX UV photometry, optical images and spectra from the Sloan Survey, IR photometry from 2MASS, WISE and IRAS along with neutral hydrogen observations from the GBT. These data permit us to describe their morphology, quantify the current high-mass star formation rate, and determine the gas and dust content. Derived properties help constrain the evolution of these particular systems in the larger context of ETGs evolving in void-like regions.

  19. SHOCK BREAKOUT AND EARLY LIGHT CURVES OF TYPE II-P SUPERNOVAE OBSERVED WITH KEPLER

    Energy Technology Data Exchange (ETDEWEB)

    Garnavich, P. M. [Department of Physics, University of Notre Dame, 225 Nieuwland Science Hall, Notre Dame, IN, 46556-5670 (United States); Tucker, B. E. [The Research School of Astronomy and Astrophysics, Australian National University, Mount Stromlo Observatory, via Cotter Road, Weston Creek, ACT 2611 (Australia); Rest, A. [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Shaya, E. J.; Olling, R. P. [Astronomy Department, University of Maryland, College Park, MD 20742-2421 (United States); Kasen, D [Department of Physics and Astronomy, University of California, Berkeley, CA 94720-3411 (United States); Villar, A. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States)

    2016-03-20

    We discovered two transient events in the Kepler field with light curves that strongly suggest they are type II-P supernovae (SNe II-P). Using the fast cadence of the Kepler observations we precisely estimate the rise time to maximum for KSN2011a and KSN2011d as 10.5 ± 0.4 and 13.3 ± 0.4 rest-frame days, respectively. Based on fits to idealized analytic models, we find the progenitor radius of KSN2011a (280 ± 20 R{sub ⊙}) to be significantly smaller than that for KSN2011d (490 ± 20 R{sub ⊙}), but both have similar explosion energies of 2.0 ± 0.3 × 10{sup 51} erg. The rising light curve of KSN2011d is an excellent match to that predicted by simple models of exploding red supergiants (RSG). However, the early rise of KSN2011a is faster than the models predict, possibly due to the supernova shock wave moving into pre-existing wind or mass-loss from the RSG. A mass-loss rate of 10{sup −4}M{sub ⊙} yr{sup −1} from the RSG can explain the fast rise without impacting the optical flux at maximum light or the shape of the post-maximum light curve. No shock breakout emission is seen in KSN2011a, but this is likely due to the circumstellar interaction suspected in the fast rising light curve. The early light curve of KSN2011d does show excess emission consistent with model predictions of a shock breakout. This is the first optical detection of a shock breakout from a SNe II-P.

  20. The SLUGGS Survey: Wide-field Stellar Kinematics of Early-type Galaxies

    Science.gov (United States)

    Arnold, Jacob A.; Romanowsky, Aaron J.; Brodie, Jean P.; Forbes, Duncan A.; Strader, Jay; Spitler, Lee R.; Foster, Caroline; Blom, Christina; Kartha, Sreeja S.; Pastorello, Nicola; Pota, Vincenzo; Usher, Christopher; Woodley, Kristin A.

    2014-08-01

    We present stellar kinematics of 22 nearby early-type galaxies (ETGs), based on two-dimensional (2D) absorption line stellar spectroscopy out to ~2-4 R e (effective radii), as part of the ongoing SLUGGS Survey. The galaxies span a factor of 20 in intrinsic luminosity, as well as a full range of environment and ETG morphology. Our data consist of good velocity resolution (σinst ~ 25 km s-1) integrated stellar-light spectra extracted from the individual slitlets of custom made Keck/DEIMOS slitmasks. We extract stellar kinematics measurements (V, σ, h 3, and h 4) for each galaxy. Combining with literature values from smaller radii, we present 2D spatially resolved maps of the large-scale kinematic structure in each galaxy. We find that the kinematic homogeneity found inside 1 R e often breaks down at larger radii, where a variety of kinematic behaviors are observed. While central slow rotators remain slowly rotating in their halos, central fast rotators show more diversity, ranging from rapidly increasing to rapidly declining specific angular momentum profiles in the outer regions. There are indications that the outer trends depend on morphological type, raising questions about the proposed unification of the elliptical and lenticular (S0) galaxy families in the ATLAS3D survey. Several galaxies in our sample show multiple lines of evidence for distinct disk components embedded in more slowly rotating spheroids, and we suggest a joint photometric-kinematic approach for robust bulge-disk decomposition. Our observational results appear generally consistent with a picture of two-phase (in-situ plus accretion) galaxy formation.

  1. The SLUGGS survey: wide-field stellar kinematics of early-type galaxies

    Energy Technology Data Exchange (ETDEWEB)

    Arnold, Jacob A. [Department of Astronomy and Astrophysics, University of California, Santa Cruz, CA 95064 (United States); Romanowsky, Aaron J.; Brodie, Jean P.; Woodley, Kristin A. [University of California Observatories, 1156 High Street, Santa Cruz, CA 95064 (United States); Forbes, Duncan A.; Blom, Christina; Kartha, Sreeja S.; Pastorello, Nicola; Pota, Vincenzo; Usher, Christopher [Centre for Astrophysics and Supercomputing, Swinburne University, Hawthorn, VIC 3122 (Australia); Strader, Jay [Department of Physics and Astronomy, Michigan State University, East Lansing, MI 48824 (United States); Spitler, Lee R. [Department of Physics and Astronomy, Faculty of Sciences, Macquarie University, Sydney, NSW 2109 (Australia); Foster, Caroline, E-mail: romanow@ucolick.org [Australian Astronomical Observatory, P.O. Box 915, North Ryde, NSW (Australia)

    2014-08-20

    We present stellar kinematics of 22 nearby early-type galaxies (ETGs), based on two-dimensional (2D) absorption line stellar spectroscopy out to ∼2-4 R {sub e} (effective radii), as part of the ongoing SLUGGS Survey. The galaxies span a factor of 20 in intrinsic luminosity, as well as a full range of environment and ETG morphology. Our data consist of good velocity resolution (σ{sub inst} ∼ 25 km s{sup –1}) integrated stellar-light spectra extracted from the individual slitlets of custom made Keck/DEIMOS slitmasks. We extract stellar kinematics measurements (V, σ, h {sub 3}, and h {sub 4}) for each galaxy. Combining with literature values from smaller radii, we present 2D spatially resolved maps of the large-scale kinematic structure in each galaxy. We find that the kinematic homogeneity found inside 1 R {sub e} often breaks down at larger radii, where a variety of kinematic behaviors are observed. While central slow rotators remain slowly rotating in their halos, central fast rotators show more diversity, ranging from rapidly increasing to rapidly declining specific angular momentum profiles in the outer regions. There are indications that the outer trends depend on morphological type, raising questions about the proposed unification of the elliptical and lenticular (S0) galaxy families in the ATLAS{sup 3D} survey. Several galaxies in our sample show multiple lines of evidence for distinct disk components embedded in more slowly rotating spheroids, and we suggest a joint photometric-kinematic approach for robust bulge-disk decomposition. Our observational results appear generally consistent with a picture of two-phase (in-situ plus accretion) galaxy formation.

  2. Stratifying the risk of lymph node metastasis in undifferentiated-type early gastric cancer

    Science.gov (United States)

    Asakawa, Yukiko; Ohtaka, Masahiko; Maekawa, Shinya; Fukasawa, Mitsuharu; Nakayama, Yasuhiro; Yamaguchi, Tatsuya; Inoue, Taisuke; Uetake, Tomoyoshi; Sakamoto, Minoru; Sato, Tadashi; Kawaguchi, Yoshihiko; Fujii, Hideki; Mochizuki, Kunio; Hada, Masao; Oyama, Toshio; Yasumura, Tomotaka; Omata, Kosaku; Nishiyama, Atsushi; Naito, Keiichi; Hata, Hideo; Haba, Yoshiaki; Miyata, Kazuyuki; Saitoh, Haruhisa; Yamadera, Yoichi; Miura, Kazuo; Kawaoi, Akira; Abe, Tohru; Tsunoda, Hajime; Honda, Yuji; Kurosaki, Masayuki; Enomoto, Nobuyuki

    2015-01-01

    AIM: To study how lymph node metastasis (LNM) risk is stratified in undifferentiated-type early gastric cancer (undiff-EGC) dependent on combinations of risk factors. METHODS: Five hundred and sixty-seven cases with undiff-EGC undergoing gastrectomy with lymphadenectomy were examined retrospectively. Using clinicopathological factors of patient age, location, size, an endoscopic macroscopic tumor form, ulceration, depth, histology, lymphatic involvement (LI) and venous involvement (VI), LNM risk was examined and stratified by conventional statistical analysis and data-mining analysis. RESULTS: LNM was positive in 44 of 567 cases (7.8%). Univariate analysis revealed > 2 cm, protrusion, submucosal (sm), mixed type, LI and VI as significant prognostic factors and > 2 cm and LI-positive were independent factors by multivariate analysis. In preoperatively evaluable factors excluding LVI, sm and > 2 cm were independent factors. According to the depth and size, cases were categorized into the low-risk group [m and ≤ 2 cm, 0% (LNM incidence)], the moderate-risk group (m and > 2 cm, 5.6%; and sm and ≤ 2 cm, 6.0%), and the high-risk group (sm and > 2 cm, 19.3%). On the other hand, LNM occurred in 1.4% in all LI-negative cases, greatly lower than 28.2% in all LI-positive cases, and LNM incidence was low in LI-negative cases even in the moderate- and high-risk groups. CONCLUSION: LNM-related factors in undiff-EGC were depth and size preoperatively while those were LI and size postoperatively. Among these factors, LI was the most significantly correlated factor. PMID:25759537

  3. Radio continuum detection in blue early-type weak emission line galaxies

    CERN Document Server

    Paswan, A

    2016-01-01

    The star formation rates (SFRs) in weak emission line (WEL) galaxies in a volume-limited ($0.02 < z < 0.05$) sample of blue early-type galaxies (ETGs) identified from SDSS, are constrained here using 1.4 GHz radio continuum emission. The direct detection of 1.4 GHz radio continuum emission is made in 8 WEL galaxies and a median stacking is performed on 57 WEL galaxies using VLA FIRST images. The median stacked 1.4 GHz flux density and luminosity are estimated as 79 $\\pm$ 19 $\\mu$Jy and 0.20 $\\pm$ 0.05 $\\times$ 10$^{21}$ W Hz$^{-1}$ respectively. The radio far-infrared correlation in 4 WEL galaxies suggests that the radio continuum emission from WEL galaxies is most likely due to star formation activities. The median SFR for WEL galaxies is estimated as 0.23 $\\pm$ 0.06 M$_{\\odot}$yr$^{-1}$, which is much less compared to SFRs ($0.5 - 50$ M$_{\\odot}$yr$^{-1}$) in purely star forming blue ETGs. The SFRs in blue ETGs are found to be correlated with their stellar velocity dispersions ($\\sigma$) and decreasin...

  4. The ACS Virgo Cluster Survey. XII. The Luminosity Function of Globular Clusters in Early Type Galaxies

    CERN Document Server

    Jordan, A; Côté, P; Ferrarese, L; Peng, E W; Mei, S; Villegas, D; Merritt, D; Tonry, J L; West, M J; Jordan, Andres; Laughlin, Dean E. Mc; Cote, Patrick; Ferrarese, Laura; Peng, Eric W.; Mei, Simona; Villegas, Daniela; Merritt, David; Tonry, John L.; West, Michael J.

    2007-01-01

    We analyze the luminosity function of the globular clusters (GCs) belonging to the early-type galaxies observed in the ACS Virgo Cluster Survey. We have obtained estimates for a Gaussian representation of the GC luminosity function (GCLF) for 89 galaxies. We have also fit the GCLFs with an "evolved Schechter function", which is meant to reflect the preferential depletion of low-mass GCs, primarily by evaporation due to two-body relaxation, from an initial Schechter mass function similar to that of young massive clusters. We find a significant trend of the GCLF dispersion with galaxy luminosity, in the sense that smaller galaxies have narrower GCLFs. We show that this narrowing of the GCLF in a Gaussian description is driven by a steepening of the GC mass function above the turnover mass, as one moves to smaller host galaxies. We argue that this behavior at the high-mass end of the GC mass function is most likely a consequence of systematic variations of the initial cluster mass function. The GCLF turnover mas...

  5. Prevention or early cure of type 1 diabetes by intranasal administration of gliadin in NOD mice.

    Directory of Open Access Journals (Sweden)

    David P Funda

    Full Text Available Induction of long-term tolerance to β-cell autoantigens has been investigated both in animal models and in human type 1 diabetes (T1D in order to prevent the disease. As regards external compounds, the dietary plant protein fraction has been associated with high penetrance of the disease, whereas gluten-free diets prevent T1D in animal models. Herewith we investigated whether intranasal (i.n. administration of gliadin or gluten may arrest the diabetogenic process. I.n. administration of gliadin to 4-week-old NOD mice significantly reduced the diabetes incidence. Similarly, the insulitis was lowered. Intranasal gliadin also rescued a fraction of prediabetic 13-week-old NOD mice from progressing to clinical onset of diabetes compared to OVA-treated controls. Vaccination with i.n. gliadin led to an induction of CD4(+Foxp3(+ T cells and even more significant induction of γδ T cells in mucosal, but not in non-mucosal lymphoid compartments. This prevention strategy was characterized by an increased proportion of IL-10 and a decreased proportion of IL-2, IL-4 and IFN-γ-positive CD4(+Foxp3(+ T cells, and IFN-γ-positive γδ T cells, preferentially in mucosal lymphoid organs. In conclusion, i.n. vaccination with gliadin, an environmental antigen with possible etiological influence in T1D, may represent a novel, safer strategy for prevention or even early cure of T1D.

  6. A systematic variation of the stellar initial mass function in early-type galaxies

    CERN Document Server

    Cappellari, Michele; Alatalo, Katherine; Blitz, Leo; Bois, Maxime; Bournaud, Frederic; Bureau, M; Crocker, Alison F; Davies, Roger L; Davis, Timothy A; de Zeeuw, P T; Duc, Pierre-Alain; Emsellem, Eric; Khochfar, Sadegh; Krajnovic, Davor; Kuntschner, Harald; Lablanche, Pierre-Yves; Morganti, Raffaella; Naab, Thorsten; Oosterloo, Tom; Sarzi, Marc; Scott, Nicholas; Serra, Paolo; Weijmans, Anne-Marie; Young, Lisa M

    2012-01-01

    Much of our knowledge of galaxies comes from analysing the radiation emitted by their stars. It depends on the stellar initial mass function (IMF) describing the distribution of stellar masses when the population formed. Consequently knowledge of the IMF is critical to virtually every aspect of galaxy evolution. More than half a century after the first IMF determination, no consensus has emerged on whether it is universal in different galaxies. Previous studies indicated that the IMF and the dark matter fraction in galaxy centres cannot be both universal, but they could not break the degeneracy between the two effects. Only recently indications were found that massive elliptical galaxies may not have the same IMF as our Milky Way. Here we report unambiguous evidence for a strong systematic variation of the IMF in early-type galaxies as a function of their stellar mass-to-light ratio, producing differences up to a factor of three in mass. This was inferred from detailed dynamical models of the two-dimensional ...

  7. Early experience of robotic surgery for type I congenital dilatation of the bile duct.

    Science.gov (United States)

    Naitoh, Takeshi; Morikawa, Takanori; Tanaka, Naoki; Aoki, Takeshi; Ohtsuka, Hideo; Okada, Takaho; Sakata, Naoaki; Ohnuma, Shinobu; Nakagawa, Kei; Hayashi, Hiroki; Musha, Hiroaki; Yoshida, Hiroshi; Motoi, Fuyuhiko; Katayose, Yu; Unno, Michiaki

    2015-06-01

    Laparoscopic surgery for this disease is not widely spread due to difficulties in its procedure. We started a laparoscopic procedure for this disease since 2011, and the robotic surgery since 2012. The aim of this study is to assess early results of these procedures. We have operated seven cases from September 2011 through December 2013. First two cases were performed by laparoscopic procedure, and following cases were done by robotically assisted surgery. Of these cases, the perioperative outcome and short-term postoperative morbidity were evaluated. Their average age was 43.6 years old (20-64 years old), and male-female ratio was 2:5. Todani classification was type 1 in all cases. The operation time was 321 min in laparoscopic cases, while 489 min in robotic surgery cases. One case of robotic surgery developed postoperative intestinal obstruction of the biliary limb, requiring laparoscopic adhesiolysis. Pancreatic fistula and anastomotic leakage have not been observed. The robotic surgery for the congenital dilatation of the bile duct is feasible and is a theoretically useful option, especially for hepatico-jejunostomy. On the other hand, the limitation of energy devices, high running cost, and time consumption remain questionable.

  8. Structure and Kinematics of Early-Type Galaxies from Integral-Field Spectroscopy

    CERN Document Server

    Cappellari, Michele

    2016-01-01

    Observations of galaxy isophotes, longs-slit kinematics and high-resolution photometry suggested a possible dichotomy between two distinct classes of E galaxies. But these methods are expensive for large galaxy samples. Instead, integral-field spectroscopic can efficiently recognize the shape, dynamics and stellar population of complete samples of early-type galaxies (ETGs). These studies showed that the two main classes, the fast and slow rotators, can be separated using stellar kinematics. We showed there is a dichotomy in the dynamics of the two classes. The slow rotators are weakly triaxial and dominate above $M_{\\rm crit}\\approx2\\times10^{11} M_\\odot$. Below $M_{\\rm crit}$, the structure of fast rotators parallels that of spiral galaxies. There is a smooth sequence along which, the metals content, the enhancement in $\\alpha$-elements, and the "weight" of the stellar initial mass function, all increase with the CENTRAL mass density slope, or bulge mass fraction, while the molecular gas fraction correspond...

  9. Early-type galaxies at z~1.3. IV. Scaling relations in different environments

    CERN Document Server

    Raichoor, A; Stanford, S A; Holden, B P; Nakata, F; Rosati, P; Shankar, F; Ford, H; Huertas-Company, M; Illingworth, G; Kodama, T; Postman, M; Rettura, A; Blakeslee, J P; Demarco, R; Jee, M J; Tanaka, M; White, R L

    2011-01-01

    We present the Kormendy and mass-size relations for early-type galaxies (ETGs) as a function of environment at z ~ 1.3. Our sample includes 76 ETGs in the Lynx supercluster and in the GOODS/CDF-S field, 31 ETGs in clusters, 18 in groups and 27 in the field, all with multi-wavelength photometry and HST/ACS observations and masses in the range 10^10 < M/Msun < 10^11.5. The Kormendy relation, in place at z ~ 1.3, does not depend on the environment. The mass-size relation reveals that ETGs overall appear to be more compact in denser environments: cluster ETGs have sizes on average twice as smaller than in the local universe, whereas field ETGs show a mass-size relation with a similar distribution than the local one. Our results imply that (1) the mass-size relation in the field did not evolve overall from z ~ 1.3 to present; (2) in denser environments, either ETGs sizes have evolved on average to twice their size, or more ETGs have been formed within the dense environment from not ETG progenitors or larger ...

  10. Star formation histories of early-type galaxies. I Higher order Balmer lines as age indicators

    CERN Document Server

    Caldwell, N; Concannon, K D; Caldwell, Nelson; Rose, James A.; Concannon, Kristi Dendy

    2003-01-01

    (shortened) We have obtained blue integrated spectra of 175 nearby early-type galaxies, covering a wide range in galaxy velocity dispersion, and emphasizing those with sigma < 100 km/s. Galaxies have been observed both in the Virgo cluster and in lower-density environments. The main goals are the evaluation of higher order Balmer lines as age indicators, and differences in stellar populations as a function of mass, environment and morphology. In this first paper our emphasis is on presenting the evolutionary population synthesis models. Lower-sigma galaxies exhibit a substantially greater intrinsic scatter, in a variety of line strength indicators, than do higher-sigma galaxies, with the large intrinsic scatter setting in below a sigma of 100 km/s. Modeling of the observed spectral indices indicates that the strong Balmer lines found primarily among the low-sigma galaxies are caused by young age, rather than by low metallicity. Thus we find a trend between the population age and the velocity dispersion, su...

  11. Herschel and JCMT observations of the early-type dwarf galaxy NGC 205

    CERN Document Server

    De Looze, I; Parkin, T J; Wilson, C D; Bendo, G J; Boquien, M; Boselli, A; Cooray, A; Cormier, D; Fritz, J; Galliano, F; Gear, W; Gentile, G; Lebouteillier, V; Madden, S C; Roussel, H; Sauvage, M; Smith, M W L; Spinoglio, L; Verstappen, J; Young, L

    2012-01-01

    We present Herschel dust continuum, James Clerk Maxwell Telescope CO(3-2) observations and a search for [CII] 158 micron and [OI] 63 micron spectral line emission for the brightest early-type dwarf satellite of Andromeda, NGC 205. While direct gas measurements (Mgas ~ 1.5e+6 Msun, HI + CO(1-0)) have proven to be inconsistent with theoretical predictions of the current gas reservoir in NGC 205 (> 1e+7 Msun), we revise the missing interstellar medium mass problem based on new gas mass estimates (CO(3-2), [CII], [OI]) and indirect measurements of the interstellar medium content through dust continuum emission. Based on Herschel observations, covering a wide wavelength range from 70 to 500 micron, we are able to probe the entire dust content in NGC 205 (Mdust ~ 1.1-1.8e+4 Msun at Tdust ~ 18-22 K) and rule out the presence of a massive cold dust component (Mdust ~ 5e+5 Msun, Tdust ~ 12 K), which was suggested based on millimeter observations from the inner 18.4 arcsec. Assuming a reasonable gas-to-dust ratio of ~ ...

  12. Re-examining the effects of verbal instructional type on early stage motor learning.

    Science.gov (United States)

    Bobrownicki, Ray; MacPherson, Alan C; Coleman, Simon G S; Collins, Dave; Sproule, John

    2015-12-01

    The present study investigated the differential effects of analogy and explicit instructions on early stage motor learning and movement in a modified high jump task. Participants were randomly assigned to one of three experimental conditions: analogy, explicit light (reduced informational load), or traditional explicit (large informational load). During the two-day learning phase, participants learned a novel high jump technique based on the 'scissors' style using the instructions for their respective conditions. For the single-day testing phase, participants completed both a retention test and task-relevant pressure test, the latter of which featured a rising high-jump-bar pressure manipulation. Although analogy learners demonstrated slightly more efficient technique and reported fewer technical rules on average, the differences between the conditions were not statistically significant. There were, however, significant differences in joint variability with respect to instructional type, as variability was lowest for the analogy condition during both the learning and testing phases, and as a function of block, as joint variability decreased for all conditions during the learning phase. Findings suggest that reducing the informational volume of explicit instructions may mitigate the deleterious effects on performance previously associated with explicit learning in the literature.

  13. Tidal Interaction as the origin of early-type dwarf galaxies in group environment

    CERN Document Server

    Paudel, Sanjaya

    2014-01-01

    We present a sample of dwarf galaxies that suffer ongoing disruption by the tidal force of nearby massive galaxies. Analysing structural and stellar population properties using the archival imaging and spectroscopic data from the Sloan Digital Sky Survey (SDSS), we find that they are likely a `smoking gun' example of the formation of early-type dwarf galaxies (dEs) in the galaxy group environment through the tidal stirring. Inner cores of these galaxies are fairly intact and the observed light profiles are well fitted with the Sersic functions, while the tidally stretched stellar halos are prominent in the outer parts. They are all located within the 50 kpc sky-projected distance from the center of host galaxies and no dwarf galaxies have relative line-of-sight velocity larger than 205 km/s to their hosts. We derive the Composite Stellar Population (CSP) properties these galaxies by fitting the SDSS optical spectra to a multiple-burst composite stellar population model. We find that these galaxies accumulate ...

  14. The luminosity and stellar mass Fundamental Plane of early-type galaxies

    CERN Document Server

    Hyde, J B

    2008-01-01

    From a sample of ~50000 early-type galaxies from the SDSS, we measured the traditional Fundamental Plane in four bands. We then replaced luminosity with stellar mass, and measured the "stellar mass" FP. The FP steepens slightly as one moves from shorter to longer wavelengths: the orthogonal fit has slope 1.40 in g and 1.47 in z. The FP is thinner at longer wavelengths: scatter is 0.062 dex in g, 0.054 dex in z. The scatter is larger at small galaxy sizes/masses; at large masses measurement errors account for essentially all of the observed scatter. The FP steepens further when luminosity is replaced with stellar mass, to slope ~ 1.6. The intrinsic scatter also reduces further, to 0.048 dex. Since color and stellar mass-to-light ratio are closely related, this explains why color can be thought of as the fourth FP parameter. However, the slope of the stellar mass FP remains shallower than the value of 2 associated with the virial theorem. This is because the ratio of dynamical to stellar mass increases at large...

  15. The SLUGGS Survey: Wide-Field Stellar Kinematics of Early-Type Galaxies

    CERN Document Server

    Arnold, Jacob A; Brodie, Jean P; Forbes, Duncan A; Strader, Jay; Spitler, Lee R; Foster, Caroline; Kartha, Sreeja S; Pastorello, Nicola; Pota, Vincenzo; Usher, Christopher; Woodley, Kristin A

    2013-01-01

    We present stellar kinematics of 22 nearby early-type galaxies (ETGs), based on two-dimensional (2D) absorption line stellar spectroscopy out to ~2-4 R_e (effective radii), as part of the ongoing SLUGGS survey. The galaxies span a factor of 20 in intrinsic luminosity, as well as a full range of environment and ETG morphology. Our data consist of good velocity resolution sigma_inst ~ 25 km/s integrated stellar-light spectra extracted from the individual slitlets of custom made Keck/DEIMOS slitmasks. We extract stellar kinematics measurements (V, sigma, h_3, and h_4) for each galaxy. Combining with literature values from smaller radii we present 2D spatially resolved maps of the large-scale kinematic structure in each galaxy. We find that the kinematic homogeneity found inside 1 R_e often breaks down at larger radii, where a variety of kinematic behaviors are observed. While central slow rotators remain slowly rotating in their halos, central fast rotators show more diversity, ranging from rapidly increasing to...

  16. The early-type dwarf galaxy population of the Centaurus cluster

    CERN Document Server

    Misgeld, I; Mieske, S

    2009-01-01

    We present a photometric study of the early-type dwarf galaxy population of the Centaurus cluster, aiming at investigating the galaxy luminosity function (LF) and galaxy scaling relations down to the regime of galaxies with M_V~-10 mag. On deep VLT/FORS1 V- and I-band images of the central part of the cluster, we identify cluster dwarf-galaxy candidates using both morphological and surface brightness selection criteria. Photometric and structural parameters of the candidates are derived from analysis of their surface brightness profiles. Fundamental scaling relations, such as the colour-magnitude and the magnitude-surface brightness relation, are used to distinguish the cluster from the background. We find a flat LF with a slope of \\alpha = -1.14 \\pm 0.12 for M_V>-14 mag, when fitting a power law to the completeness-corrected galaxy number counts. When plotting the central surface brightness of a Sersic model vs. the galaxy magnitude, we find a continuous relation for magnitudes -20

  17. Colour gradients of high-redshift Early-Type Galaxies from hydrodynamical monolithic models

    CERN Document Server

    Tortora, C; D'Ercole, A; Napolitano, N R; Matteucci, F

    2013-01-01

    We analyze the evolution of colour gradients predicted by the hydrodynamical models of early type galaxies (ETGs) in Pipino et al. (2008), which reproduce fairly well the chemical abundance pattern and the metallicity gradients of local ETGs. We convert the star formation (SF) and metal content into colours by means of stellar population synthetic model and investigate the role of different physical ingredients, as the initial gas distribution and content, and eps_SF, i.e. the normalization of SF rate. From the comparison with high redshift data, a full agreement with optical rest-frame observations at z < 1 is found, for models with low eps_SF, whereas some discrepancies emerge at 1 < z < 2, despite our models reproduce quite well the data scatter at these redshifts. To reconcile the prediction of these high eps_SF systems with the shallower colour gradients observed at lower z we suggest intervention of 1-2 dry mergers. We suggest that future studies should explore the impact of wet galaxy mergings...

  18. Systematic variations of central mass density slopes in early-type galaxies

    CERN Document Server

    Tortora, C; Napolitano, N R; Romanowsky, A J; Ferreras, I; de Carvalho, R R

    2014-01-01

    We study the total density distribution in the central regions (~ 1 effective radius, $R_e$) of early-type galaxies (ETGs), using data from SPIDER and $\\rm ATLAS^{3D}$. Our analysis extends the range of galaxy stellar mass ($M_{\\star}$) probed by gravitational lensing, down to ~ $10^{10}\\, \\rm M_{\\odot}$. We model each galaxy with two components (dark matter halo + stars), exploring different assumptions for the dark matter (DM) halo profile (i.e. NFW, NFW-contracted, and Burkert profiles), and leaving stellar mass-to-light ($M_{\\star}/L$) ratios as free fitting parameters to the data. For all plausible halo models, the best-fitting $M_{\\star}/L$, normalized to that for a Chabrier IMF, increases systematically with galaxy size and mass. For an NFW profile, the slope of the total mass profile is non-universal, independently of several ingredients in the modeling (e.g., halo contraction, anisotropy, and rotation velocity in ETGs). For the most massive ($M_{\\star}$ ~ $10^{11.5} \\, M_{\\odot}$) or largest ($R_{\\rm...

  19. Dark Matter and IMF normalization in Virgo dwarf early-type galaxies

    CERN Document Server

    Tortora, C; Napolitano, N R

    2015-01-01

    In this work we analyze the dark matter (DM) fraction, \\fdm, and mass-to-light ratio mismatch parameter, \\dimf\\ (computed with respect to a Milky-Way-like IMF), for a sample of 39 dwarf early-type galaxies (dEs) in the Virgo cluster. Both \\fdm\\ and \\dimf\\ are estimated within the central (one effective radius) galaxy regions, with a Jeans dynamical analysis that relies on galaxy velocity dispersions, structural parameters, and stellar mass-to-light ratios from the SMAKCED survey. In this first attempt to constrain, simultaneously, the IMF normalization and the dark matter content, we explore the impact of different assumptions on the DM model profile. On average, for a NFW profile, the \\dimf\\ is consistent with a Chabrier-like normalization ($\\dimf \\sim 1$), with $\\fdm \\sim 0.35$. One of the main results of the present work is that for at least a few systems the \\dimf\\ is heavier than the Milky-Way-like value (i.e. either top- or bottom-heavy). When introducing tangential anisotropy, larger \\dimf\\ and smaller...

  20. MOND and IMF variations in early-type galaxies from $\\rm ATLAS^{3D}$

    CERN Document Server

    Tortora, C; Cardone, V F; Napolitano, N R; Jetzer, Ph

    2013-01-01

    MOdified Newtonian dynamics (MOND) represents a phenomenological alternative to dark matter (DM) for the missing mass problem in galaxies and clusters of galaxies. We analyze the central regions of a local sample of $\\sim 220$ early-type galaxies from the $\\rm ATLAS^{3D}$ survey, to see if the data can be reproduced without recourse to DM. We estimate dynamical masses in the MOND context through Jeans analysis, and compare to $\\rm ATLAS^{3D}$ stellar masses from stellar population synthesis. We find that the observed stellar mass--velocity dispersion relation is steeper than expected assuming MOND with a fixed stellar initial mass function (IMF) and a standard value for the acceleration parameter $a_{\\rm 0}$. Turning from the space of observables to model space, a) fixing the IMF, a universal value for $a_{\\rm 0}$ cannot be fitted, while, b) fixing $a_{\\rm 0}$ and leaving the IMF free to vary, we find that it is "lighter" (Chabrier-like) for low-dispersion galaxies, and "heavier" (Salpeter-like) for high disp...

  1. Systematic variation of central mass density slope in early-type galaxies

    CERN Document Server

    Tortora, C; Napolitano, N R; Romanowsky, A J; Ferreras, I; de Carvalho, R R

    2015-01-01

    We study the total density distribution in the central regions ($<\\, 1$ effective radius, $R_{\\rm e}$) of early-type galaxies (ETGs), using data from the SPIDER survey. We model each galaxy with two components (dark matter halo + stars), exploring different assumptions for the dark matter (DM) halo profile, and leaving stellar mass-to-light ($M_{\\rm \\star}/L$) ratios as free fitting parameters to the data. For a Navarro et al. (1996) profile, the slope of the total mass profile is non-universal. For the most massive and largest ETGs, the profile is isothermal in the central regions ($\\sim R_{\\rm e}/2$), while for the low-mass and smallest systems, the profile is steeper than isothermal, with slopes similar to those for a constant-M/L profile. For a concentration-mass relation steeper than that expected from simulations, the correlation of density slope with mass tends to flatten. Our results clearly point to a "non-homology" in the total mass distribution of ETGs, which simulations of galaxy formation sugg...

  2. Evolution of central dark matter of early-type galaxies up to z ~ 0.8

    CERN Document Server

    Tortora, C; Saglia, R P; Romanowsky, A J; Covone, G; Capaccioli, M

    2014-01-01

    We investigate the evolution of dark and luminous matter in the central regions of early-type galaxies (ETGs) up to z ~ 0.8. We use a spectroscopically selected sample of 154 cluster and field galaxies from the EDisCS survey, covering a wide range in redshifts (z ~ 0.4-0.8), stellar masses ($\\log M_{\\star}/ M_{\\odot}$ ~ 10.5-11.5 dex) and velocity dispersions ($\\sigma_{\\star}$ ~ 100-300 \\, km/s). We obtain central dark matter (DM) fractions by determining the dynamical masses from Jeans modelling of galaxy aperture velocity dispersions and the $M_{\\star}$ from galaxy colours, and compare the results with local samples. We discuss how the correlations of central DM with galaxy size (i.e. the effective radius, $R_{\\rm e}$), $M_{\\star}$ and $\\sigma_{\\star}$ evolve as a function of redshift, finding clear indications that local galaxies are, on average, more DM dominated than their counterparts at larger redshift. This DM fraction evolution with $z$ can be only partially interpreted as a consequence of the size-r...

  3. Dark matter inside early-type galaxies as function of mass and redshift

    Science.gov (United States)

    Nigoche-Netro, A.; Ramos-Larios, G.; Lagos, P.; Ruelas-Mayorga, A.; de la Fuente, E.; Kemp, S. N.; Navarro, S. G.; Corral, L. J.; Hidalgo-Gámez, A. M.

    2016-10-01

    We study the behaviour of the dynamical and stellar mass inside the effective radius (re) of early-type galaxies (ETGs). We use several samples of ETGs - ranging from 19 000 to 98 000 objects - from the ninth data release of the Sloan Digital Sky Survey. We consider Newtonian dynamics, different light profiles and different initial mass functions (IMF) to calculate the dynamical and stellar mass. We assume that any difference between these two masses is due to dark matter and/or a non-universal IMF. The main results for galaxies in the redshift range 0.0024 dark matter or a non-universal IMF or a combination of both; (v) the amount of dark matter inside ETGs would be equal to or less than the difference between dynamical and stellar mass depending on the impact of the IMF on the stellar mass estimation; (vi) the previous results go in the same direction of some results of the Fundamental Plane (FP) found in the literature in the sense that they could be interpreted as an increase of dark matter along the FP and a dependence of the FP on redshift.

  4. Identification of old tidal dwarfs near early-type galaxies from deep imaging and HI observations

    CERN Document Server

    Duc, Pierre-Alain; McDermid, Richard M; Cuillandre, Jean-Charles; Serra, Paolo; Bournaud, Frédéric; Cappellari, Michele; Emsellem, Eric

    2014-01-01

    It has recently been proposed that the dwarf spheroidal galaxies located in the Local Group disks of satellites (DoSs) may be tidal dwarf galaxies (TDGs) born in a major merger at least 5 Gyr ago. Whether TDGs can live that long is still poorly constrained by observations. As part of deep optical and HI surveys with the CFHT MegaCam camera and Westerbork Synthesis Radio Telescope made within the ATLAS3D project, and follow-up spectroscopic observations with the Gemini-North telescope, we have discovered old TDG candidates around several early-type galaxies. At least one of them has an oxygen abundance close to solar, as expected for a tidal origin. This confirmed pre-enriched object is located within the gigantic, but very low surface brightness, tidal tail that emanates from the elliptical galaxy, NGC 5557. An age of 4 Gyr estimated from its SED fitting makes it the oldest securely identified TDG ever found so far. We investigated the structural and gaseous properties of the TDG and of a companion located in...

  5. Nearby early-type galaxies with ionized gas VI. The Spitzer-IRS view

    CERN Document Server

    Panuzzo, P; Bressan, A; Vega, O; Annibali, F; Buson, L M; Clemens, M S; Zeilinger, W W

    2010-01-01

    We present low resolution Spitzer-IRS spectra of 40 ETGs, selected from a sample of 65 ETGs showing emission lines in their optical spectra. We homogeneously extract the mid-infrared (MIR) spectra, and after the proper subtraction of a "passive" ETG template, we derive the intensity of the ionic and molecular lines and of the polycyclic aromatic hydrocarbon emission features. We use MIR diagnostic diagrams to investigate the powering mechanisms of the ionized gas. The mid-infrared spectra of early-type galaxies show a variety of spectral characteristics. We empirically sub-divide the sample into five classes of spectra with common characteristics. Class-0, accounting for 20% of the sample, are purely passive ETGs with neither emission lines nor PAH features. Class-1 show emission lines but no PAH features, and account for 17.5% of the sample. Class-2, in which 50% of the ETGs are found, as well as having emission lines, show PAH features with unusual ratios, e.g. 7.7 {\\mu}m/11.3 {\\mu}m \\leq 2.3. Class-3 objec...

  6. The ACS Fornax Cluster Survey. XII. Diffuse Star Clusters in Early-type Galaxies

    CERN Document Server

    Liu, Yiqing; Lim, Sungsoon; Jordán, Andrés; Blakeslee, John; Côté, Patrick; Ferrarese, Laura; Pattarakijwanich, Petchara

    2016-01-01

    Diffuse star clusters (DSCs) are old and dynamically hot stellar systems that have lower surface brightness and more extended morphology than globular clusters (GCs). Using the images from HST/ACS Fornax Cluster Survey, we find that 12 out of 43 early-type galaxies (ETGs) in the Fornax cluster host significant numbers of DSCs. Together with literature data from the HST/ACS Virgo Cluster Survey, where 18 out of 100 ETGs were found to host DSCs, we systematically study the relationship of DSCs with GCs, and their host galaxy environment. Two DSC hosts are post-merger galaxies, with most of the other hosts either having low mass or showing clear disk components. We find that while the number ratio of DSCs to GCs is nearly constant in massive galaxies, the DSC-to-GC ratio becomes systematically higher in lower mass hosts. This suggests that DSCs may be more efficient at forming (or surviving) in low density environments. DSC hosts are not special either in their position in the cluster, or in the galactic color-m...

  7. The ACS Fornax Cluster Survey. XII. Diffuse Star Clusters in Early-type Galaxies

    Science.gov (United States)

    Liu, Yiqing; Peng, Eric W.; Lim, Sungsoon; Jordán, Andrés; Blakeslee, John; Côté, Patrick; Ferrarese, Laura; Pattarakijwanich, Petchara

    2016-10-01

    Diffuse star clusters (DSCs) are old and dynamically hot stellar systems that have lower surface brightness and more extended morphology than globular clusters (GCs). Using the images from Hubble Space Telescope (HST)/ACS Fornax Cluster Survey, we find that 12 out of 43 early-type galaxies (ETGs) in the Fornax Cluster host significant numbers of DSCs. Together with literature data from the HST/ACS Virgo Cluster Survey, where 18 out of 100 ETGs were found to host DSCs, we systematically study the relationship of DSCs with GCs and their host galaxy environment. Two DSC hosts are post-merger galaxies, with most of the other hosts either having low mass or showing clear disk components. We find that while the number ratio of DSCs to GCs is nearly constant in massive galaxies, the DSC-to-GC ratio becomes systematically higher in lower-mass hosts. This suggests that DSCs may be more efficient at forming (or surviving) in low-density environments. DSC hosts are not special either in their position in the cluster or in the galactic color-magnitude diagram. Why some disk and low-mass galaxies host DSCs while others do not is still a puzzle, however. The mean ages of DSC hosts and nonhosts are similar at similar masses, implying that formation efficiency rather than survival is the reason behind different DSC number fractions in ETGs.

  8. Evolutionary Status of Early-Type Galaxies in Distant Poor Clusters

    CERN Document Server

    Fritz, A

    2004-01-01

    We introduce our project that investigates the kinematic properties of early-type galaxies in 6 distant poor clusters at z~0.25. This study represents a continuation of our efforts to understand galaxy evolution in low-density environments. Higher-resolution MOSCA spectra have been obtained at the Calar Alto 3.5-m telescope with which we can measure absorption line strengths and velocity dispersions. In conjunction with our HST/F702W images of all the clusters, we are able to construct the Fundamental Plane of ellipticals and S0 galaxies in poor clusters at a look-back time of ~3 Gyrs. For galaxies outside the HST field, we concentrate our analysis on the Mg-sigma and Faber-Jackson relations. With the line strength diagrams age/metallicity distributions can be derived in densities between the field and rich cluster environments. Comparing with our rich clusters at the same cosmic epochs, the dependence of galaxy formation models on the local environment can be tested more quantitatively.

  9. The Atlas3D project - XXIV. The intrinsic shape distribution of early-type galaxies

    CERN Document Server

    Weijmans, Anne-Marie; Emsellem, Eric; Krajnovic, Davor; Lablanche, Pierre-Yves; Alatalo, Katherine; Blitz, Leo; Bois, Maxime; Bournaud, Frederic; Bureau, Martin; Cappellari, Michele; Crocker, Alison; Davies, Roger; Davis, Timothy; Duc, Pierre-Alain; Khochfar, Sadegh; Kuntschner, Harald; McDermid, Richard; Morganti, Raffaella; Naab, Thorsten; Oosterloo, Tom; Sarzi, Marc; Scott, Nicholas; Serra, Paolo; Kleijn, Gijs Verdoes; Young, Lisa

    2014-01-01

    We use the Atlas3D sample to perform a study of the intrinsic shapes of early-type galaxies, taking advantage of the available combined photometric and kinematic data. Based on our ellipticity measurements from the Sloan Digital Sky Survey Data Release 7, and additional imaging from the Isaac Newton Telescope, we first invert the shape distribution of fast and slow rotators under the assumption of axisymmetry. The so-obtained intrinsic shape distribution for the fast rotators can be described with a Gaussian with a mean flattening of q=0.25 and standard deviation sigma_q = 0.14, and an additional tail towards rounder shapes. The slow rotators are much rounder, and are well described with a Gaussian with mean q = 0.63 and sigma_q =0.09. We then checked that our results were consistent when applying a different and independent method to obtain intrinsic shape distributions, by fitting the observed ellipticity distributions directly using Gaussian parametrisations for the intrinsic axis ratios. Although both fas...

  10. Stellar age versus mass of early-type galaxies in the Virgo Cluster

    CERN Document Server

    Lisker, Thorsten

    2008-01-01

    The flux excess of elliptical galaxies in the far-ultraviolet can be reproduced by population synthesis models when accounting for the population of old hot helium-burning subdwarf stars. This has been achieved by Han and coworkers through a quantitative model of binary stellar evolution. Here, we compare the resulting evolutionary population synthesis model to the GALEX far-near ultraviolet colors (FUV-NUV) of Virgo cluster early-type galaxies that were published by Boselli and coworkers. FUV-NUV is reddest at about the dividing luminosity of dwarf and giant galaxies, and becomes increasingly blue for both brighter and fainter luminosities. This behavior can be easily explained by the binary model with a continuous sequence of longer duration and later truncation of star formation at lower galaxy masses. Thus, in contrast to previous conclusions, the GALEX data do not require a dichotomy between the stellar population properties of dwarfs and giants. Their apparently opposite behavior in FUV-NUV occurs natur...

  11. The density of dark matter haloes of early-type galaxies in low density environments

    CERN Document Server

    Corsini, E M; Thomas, J; Saglia, R P; Bender, R

    2016-01-01

    New photometric and long-slit spectroscopic observations are presented for NGC 7113, PGC 1852, and PGC 67207, which are three bright galaxies residing in low density environments. The surface-brightness distribution is analysed from K_S-band images taken with adaptive optics at the Gemini North Telescope and ugriz-band images from the Sloan Digital Sky Survey while the line-of-sight stellar velocity distribution and line-strength Lick indices inside the effective radius are measured along several position angles. The age, metallicity, and alpha-element abundance of the galaxies are estimated from single stellar-population models. In spite of the available morphological classification, images show that PGC 1852 is a barred spiral which we do not further consider for mass modelling. The structural parameters of the two early-type galaxies NGC 7113 and PGC 67207 are obtained from a two-dimensional photometric decomposition and the mass-to-light ratio of all the (luminous and dark) mass that follows the light is ...

  12. Discovery of a magnetic field in the early B-type star sigma Lupi

    CERN Document Server

    Henrichs, H F; Plaggenborg, B; Marsden, S C; Waite, I A; Landstreet, J D; Wade, G A; Grunhut, J H; Oksala, M E

    2012-01-01

    Magnetic early B-type stars are rare. To identify them, we use the strongest indirect indicator of a magnetic field in B stars, which is periodic variability of UV stellar wind lines occurring symmetric about the approximate rest wavelength. Probable magnetic candidates are targets for follow-up spectropolarimetry to search for a magnetic field. From the UV wind line variability the B1/B2V star sigma Lupi emerged as a new magnetic candidate star. AAT spectropolarimetric measurements with SEMPOL were obtained. The longitudinal component of the magnetic field integrated over the visible surface of the star was determined with the Least-Squares Deconvolution method. The UV line variations of sigma Lupi are similar to what is known in magnetic B stars, but no periodicity could be determined. We detected a varying longitudinal magnetic field with amplitude of about 100 G with error bars of typically 20 G, which supports an oblique magnetic-rotator configuration. The EW variations of the UV lines, the magnetic and ...

  13. The nuclear X-ray emission of nearby early-type galaxies

    CERN Document Server

    Pellegrini, S

    2010-01-01

    Nuclear hard X-ray luminosities (Lx,nuc) for a sample of 112 early type galaxies within a distance of 67 Mpc are used to investigate their relationship with the central galactic black hole mass Mbh, the inner galactic structure (using the parameters describing its cuspiness), the age of the stellar population in the central galactic region, the hot gas content and the core radio luminosity. Lx,nuc ranges from 10^{38} to 10^{42} erg/s, and the Eddington ratio Lx,nuc/Ledd from 10^{-9} to 10^{-4}. Lx,nuc increases on average with the galactic luminosity Lb and Mbh, with a wide variation by up to 4 orders of magnitude at any fixed Lb>6x10^9 Lb,sun or Mbh>10^7 Msun. This large range should reflect a large variation of the mass accretion rate \\dotMbh. On the circumnuclear scale, \\dotMbh at fixed Lb (or Mbh) could vary due to differences in the fuel production rate from the stellar mass return linked to the inner galactic structure; however, \\dotMbh should vary with cuspiness by a factor exceeding a few only in hot ...

  14. Star formation associated with neutral hydrogen in the outskirts of early-type galaxies

    CERN Document Server

    Yıldız, Mustafa K; Peletier, Reynier F; Oosterloo, Tom A; Duc, Pierre-Alain

    2016-01-01

    About 20 percent of all nearby early-type galaxies ($M_{\\star} \\gtrsim 6 \\times 10^{9}$ M$_{\\odot}$) outside the Virgo cluster are surrounded by a disc or ring of low-column-density neutral hydrogen (HI) gas with typical radii of tens of kpc, much larger than the stellar body. In order to understand the impact of these gas reservoirs on the host galaxies, we analyse the distribution of star formation out to large radii as a function of HI properties using GALEX UV and SDSS optical images. Our sample consists of 18 HI-rich galaxies as well as 55 control galaxies where no HI has been detected. In half of the HI-rich galaxies the radial UV profile changes slope at the position of the HI radial profile peak. To study the stellar populations, we calculate the FUV-NUV and UV-optical colours in two apertures, 1-3 and 3-10 R$_{eff}$ . We find that HI -rich galaxies are on average 0.5 and 0.8 mag bluer than the HI-poor ones, respectively. This indicates that a significant fraction of the UV emission traces recent star...

  15. Colour gradients in normal and compact early-type galaxies at 1

    CERN Document Server

    Gargiulo, A; Longhetti, M

    2010-01-01

    We have derived colour gradients for a sample of 20 early-type galaxies (ETGs) at 1 < z_spec < 2 selected from the GOODS-South field. The sample includes both normal ETGs (13) having effective radii comparable to the mean radius of local ones and compact ETGs (7) having effective radii from two to six times smaller. Colour gradients have been derived in the F606W-F850LP bands (UV-U rest-frame) taking advantage of the ultradeep HST-ACS observations covering this field and providing a spatial resolution of about 0.8 kpc at the redshift of the galaxies. Despite of the narrow wavelength baseline covered (1000 Angstrom), sampling approximatively the emission dominated by the same stellar population, we detect significant radial colour variations in 50 per cent of our sample. In particular, we find five ETGs with positive colour gradients (cores bluer than the external regions), and five galaxies with negative colour gradients (cores redder than the external regions), as commonly observed in the local Univers...

  16. Mitochondrial quality control systems sustain brain mitochondrial bioenergetics in early stages of type 2 diabetes.

    Science.gov (United States)

    Santos, R X; Correia, S C; Alves, M G; Oliveira, P F; Cardoso, S; Carvalho, C; Seiça, R; Santos, M S; Moreira, P I

    2014-09-01

    Mitochondria have a crucial role in the supply of energy to the brain. Mitochondrial alterations can lead to detrimental consequences on the function of brain cells and are thought to have a pivotal role in the pathogenesis of several neurologic disorders. This study was aimed to evaluate mitochondrial function, fusion-fission and biogenesis and autophagy in brain cortex of 6-month-old Goto-Kakizaki (GK) rats, an animal model of nonobese type 2 diabetes (T2D). No statistically significant alterations were observed in mitochondrial respiratory chain and oxidative phosphorylation system. A significant decrease in the protein levels of OPA1, a protein that facilitates mitochondrial fusion, was observed in brain cortex of GK rats. Furthermore, a significant decrease in the protein levels of LC3-II and a significant increase in protein levels of mTOR phosphorylated at serine residue 2448 were observed in GK rats suggesting a suppression of autophagy in diabetic brain cortex. No significant alterations were observed in the parameters related to mitochondrial biogenesis. Altogether, these results demonstrate that during the early stages of T2D, brain mitochondrial function is maintained in part due to a delicate balance between mitochondrial fusion-fission and biogenesis and autophagy. However, future studies are warranted to evaluate the role of mitochondrial quality control pathways in late stages of T2D.

  17. Evidence for the rapid formation of low mass early-type galaxies in dense environments

    CERN Document Server

    Liu, Yiqing; Blakeslee, John; Côté, Patrick; Ferrarese, Laura; Jordán, Andrés; Puzia, Thomas H; Toloba, Elisa; Zhang, Hong-Xin

    2015-01-01

    We explore the environmental dependence of star formation timescales in low mass galaxies using the [$\\alpha$/Fe] abundance ratio as an evolutionary clock. We present integrated [$\\alpha$/Fe] measurements for 11 low mass ($M_\\star \\sim 10^9~M_\\odot$) early-type galaxies (ETGs) with a large range of cluster-centric distance in the Virgo Cluster. We find a gradient in [$\\alpha$/Fe], where the galaxies closest to the cluster center (the cD galaxy, M87) have the highest values. This trend is driven by galaxies within a projected radius of 0.4~Mpc (0.26 times the virial radius of Virgo~A), all of which have super-solar [$\\alpha$/Fe]. Galaxies in this mass range exhibit a large scatter in the [$\\alpha$/Fe]--$\\sigma$ diagram, and do not obviously lie on an extension of the relation defined by massive ETGs. In addition, we find a correlation between [$\\alpha$/Fe] and globular cluster specific frequency ($S_N$), suggesting that low-mass ETGs that formed their stars over a short period of time, were also efficient at f...

  18. IFU spectroscopy of 10 early-type galactic nuclei - IV. Properties of the circumnuclear stellar kinematics

    CERN Document Server

    Ricci, T V; Menezes, R B

    2016-01-01

    The study of stellar kinematic properties may provide hints on the formation and evolution of elliptical and lenticular galaxies. Although most previous studies have focused on the large scale of these galaxies, their central regions (scales of $\\sim$ 100 pc) may contain important clues about their structure, such as kinematically decoupled cores. This is the fourth paper on a sample of 10 massive ($\\sigma$ $>$ 200 km s$^{-1}$) and nearby ($d$ $<$ 31 Mpc) early-type galaxies, observed with the integral field unit of the Gemini South Multi Object Spectrograph. Here, we analyse the properties of the stellar kinematics in the circumnuclear region. We fitted the line-of-sight velocity distribution with a Gauss-Hermite function. In seven galaxies of the sample, we detected a rotation pattern in their radial velocity maps that are anti-correlated with $h_3$. We interpret this as stellar structures in rotation embedded in the bulges of the objects. Comparing the stellar kinematic results with the PCA Tomography r...

  19. The Virial Relation and Intrinsic Shape of Early-Type Galaxies

    CERN Document Server

    Trippe, Sascha

    2016-01-01

    Early-type galaxies (ETGs) are supposed to follow the virial relation $M = k_e \\sigma_*^2 R_e / G$, with $M$ being the mass, $\\sigma_*$ being the stellar velocity dispersion, $R_e$ being the effective radius, $G$ being Newton's constant, and $k_e$ being the virial factor, a geometry factor of order unity. Applying this relation to (a) the \\atlas\\ sample of \\citet{cappellari2013a} and (b) the sample of \\cite{saglia2016} gives ensemble-averaged factors $\\langle k_e\\rangle =5.15\\pm0.09$ and $\\langle k_e\\rangle =4.01\\pm0.18$, respectively, with the difference arising from different definitions of effective velocity dispersions. The two datasets reveal a statistically significant tilt of the empirical relation relative to the theoretical virial relation such that $M\\propto(\\sigma_*^2R_e)^{0.92}$. This tilt disappears when replacing $R_e$ with the semi-major axis of the projected half-light ellipse, $a$. All best-fit scaling relations show zero intrinsic scatter, implying that the mass plane of ETGs is fully determ...

  20. The SLUGGS Survey: Kinematics for over 2500 Globular Clusters in Twelve Early-type Galaxies

    CERN Document Server

    Pota, Vincenzo; Romanowsky, Aaron J; Brodie, Jean P; Spitler, Lee R; Strader, Jay; Foster, Caroline; Arnold, Jacob A; Benson, Andrew; Blom, Christina; Hargis, Jonathan R; Rhode, Katherine L; Usher, Christopher

    2012-01-01

    We present a spectro-photometric survey of 2522 extragalactic globular clusters (GCs) around twelve early-type galaxies, nine of which have not been published previously. Combining space-based and multi-colour wide field ground-based imaging, with spectra from the Keck DEIMOS instrument, we obtain an average of 160 GC radial velocities per galaxy, with a high velocity precision of 15 km/s per GC. After studying the photometric properties of the GC systems, such as their spatial and colour distributions, we focus on the kinematics of metal-poor (blue) and metal-rich (red) GC subpopulations to an average distance of ~8 effective radii from the galaxy centre. Our results show that for some systems the bimodality in GC colour is also present in GC kinematics. The kinematics of the red GC subpopulations are strongly coupled with the host galaxy stellar kinematics. The blue GC subpopulations are more dominated by random motions, especially in the outer regions, and decoupled from the red GCs. Peculiar GC kinematic ...

  1. The SLUGGS Survey: globular clusters and the dark matter content of early-type galaxies

    CERN Document Server

    Forbes, Duncan A; Romanowsky, Aaron J; Brodie, Jean P; Strader, Jay; Usher, Christopher; Pota, Vincenzo

    2016-01-01

    A strong correlation exists between the total mass of a globular cluster (GC) system and the virial halo mass of the host galaxy. However, the total halo mass in this correlation is a statistical measure conducted on spatial scales that are some ten times that of a typical GC system. Here we investigate the connection between GC systems and galaxy's dark matter on comparable spatial scales, using dynamical masses measured on a galaxy-by-galaxy basis. Our sample consists of 17 well-studied massive (stellar mass $\\sim$10$^{11}$ M$_{\\odot}$) early-type galaxies from the SLUGGS survey. We find the strongest correlation to be that of the blue (metal-poor) GC subpopulation and the dark matter content. This correlation implies that the dark matter mass of a galaxy can be estimated to within a factor of two from careful imaging of its GC system. The ratio of the GC system mass to that of the enclosed dark matter is nearly constant. We also find a strong correlation between the fraction of blue GCs and the fraction of...

  2. Shock Breakout and Early Light Curves of Type II-P Supernovae Observed with Kepler

    CERN Document Server

    Garnavich, P M; Rest, A; Shaya, E J; Olling, R P; Kasen, D; Villar, A

    2016-01-01

    We discovered two transient events in the Kepler field with light curves that strongly suggest they are type II-P supernovae. Using the fast cadence of the Kepler observations we precisely estimate the rise time to maximum for KSN2011a and KSN2011d as 10.5$\\pm 0.4$ and 13.3$\\pm 0.4$ rest-frame days respectively. Based on fits to idealized analytic models, we find the progenitor radius of KSN2011a (280$\\pm 20$ R$_\\odot$) to be significantly smaller than that for KSN2011d (490$\\pm 20$ R$_\\odot$) but both have similar explosion energies of 2.0$\\pm 0.3\\times 10^{51}$ erg. The rising light curve of KSN2011d is an excellent match to that predicted by simple models of exploding red supergiants (RSG). However, the early rise of KSN2011a is faster than the models predict possibly due to the supernova shockwave moving into pre-existing wind or mass-loss from the RSG. A mass loss rate of $10^{-4}$ M$_\\odot$ yr$^{-1}$ from the RSG can explain the fast rise without impacting the optical flux at maximum light or the shape ...

  3. NOT DEAD YET: COOL CIRCUMGALACTIC GAS IN THE HALOS OF EARLY-TYPE GALAXIES

    Energy Technology Data Exchange (ETDEWEB)

    Thom, Christopher; Tumlinson, Jason; Sembach, Kenneth R. [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Werk, Jessica K.; Xavier Prochaska, J. [UCO/Lick Observatory, University of California, Santa Cruz, CA 95064 (United States); Oppenheimer, Benjamin D. [Leiden Observatory, Leiden University, P.O. Box 9513, NL-2300 RA Leiden (Netherlands); Peeples, Molly S. [Department of Physics and Astronomy, University of California Los Angeles, Los Angeles, CA 90095 (United States); Tripp, Todd M.; Katz, Neal S. [Department of Astronomy, University of Massachusetts, Amherst, MA 01003-9305 (United States); O' Meara, John M. [Department of Chemistry and Physics, Saint Michael' s College, Colchester, VT 05439 (United States); Ford, Amanda Brady; Dave, Romeel [Steward Observatory, University of Arizona, 933 N. Cherry Avenue, Tucson, AZ 85721 (United States); Weinberg, David H. [Department of Astronomy, Ohio State University, 140 W. 18th Avenue, Columbus, OH 43210 (United States)

    2012-10-20

    We report new observations of circumgalactic gas in the halos of early-type galaxies (ETGs) obtained by the COS-Halos Survey with the Cosmic Origins Spectrograph on board the Hubble Space Telescope. We find that detections of H I surrounding ETGs are typically as common and strong as around star-forming galaxies, implying that the total mass of circumgalactic material is comparable in the two populations. For ETGs, the covering fraction for H I absorption above 10{sup 16} cm{sup -2} is {approx}40%-50% within {approx}150 kpc. Line widths and kinematics of the detected material show it to be cold (T {approx}< 10{sup 5} K) in comparison to the virial temperature of the host halos. The implied masses of cool, photoionized circumgalactic medium baryons may be up to 10{sup 9}-10{sup 11} M{sub Sun }. Contrary to some theoretical expectations, strong halo H I absorbers do not disappear as part of the quenching of star formation. Even passive galaxies retain significant reservoirs of halo baryons that could replenish the interstellar gas reservoir and eventually form stars. This halo gas may feed the diffuse and molecular gas that is frequently observed inside ETGs.

  4. Improving stellar parameter and abundance determinations of early B-type stars

    CERN Document Server

    Nieva, Maria-Fernanda

    2009-01-01

    In the past years we have made great efforts to reduce the statistical and systematic uncertainties in stellar parameter and chemical abundance determinations of early B-type stars. Both the construction of robust model atoms for non-LTE line-formation calculations and a novel self-consistent spectral analysis methodology were decisive to achieve results of unprecedented precision. They were extensively tested and applied to high-quality spectra of stars from OB associations and the field in the solar neighbourhood, covering a broad parameter range. Initially, most lines of hydrogen, helium and carbon in the optical/near-IR spectral range were reproduced simultaneously in a consistent way for the first time, improving drastically on the accuracy of results in published work.By taking additional ionization equilibria of oxygen, neon, silicon and iron into account, uncertainties as low as ~1% in effective temperature, ~10% in surface gravity and ~20% in elemental abundances are achieved - compared to ~5-10%, ~2...

  5. The history of star formation and mass assembly in early-type galaxies

    CERN Document Server

    Clemens, M S; Nikolic, B; Rampazzo, R

    2008-01-01

    We define a volume limited sample of over 14,000 early-type galaxies (ETGs) selected from data release six of the Sloan Digital Sky Survey. The density of environment of each galaxy is robustly measured. By comparing narrow band spectral line indices with recent models of simple stellar populations (SSPs) we investigate trends in the star formation history as a function of galaxy mass (velocity dispersion), density of environment and galactic radius. We find that age, metallicity and alpha-enhancement all increase with galaxy mass and that field ETGs are younger than their cluster counterparts by ~2 Gyr. We find negative radial metallicity gradients for all masses and environments, and positive radial age gradients for ETGs with velocity dispersion over 180 km/s. Our results are qualitatively consistent with a relatively simple picture for ETG evolution in which the low-mass halos accreted by a proto-ETG contained not only gas but also a stellar population. This fossil population is preferentially found at la...

  6. Testing the Presence of Multiple Photometric Components in Nearby Early-type Galaxies using SDSS

    Science.gov (United States)

    Oh, Semyeong; Greene, Jenny E.; Lackner, Claire N.

    2017-02-01

    We investigate two-dimensional image decomposition of nearby, morphologically selected early-type galaxies (ETGs). We are motivated by recent observational evidence of significant size growth of quiescent galaxies and theoretical development advocating a two-phase formation scenario for ETGs. We find that a significant fraction of nearby ETGs show changes in isophotal shape that require multi-component models. The characteristic sizes of the inner and outer component are ∼3 and ∼15 kpc. The inner component lies on the mass–size relation of ETGs at z ∼ 0.25–0.75, while the outer component tends to be more elliptical and hints at a stochastic buildup process. We find real physical differences between single- and double-component ETGs, with double-component galaxies being younger and more metal-rich. The fraction of double-component ETGs increases with increasing σ and decreases in denser environments. We hypothesize that double-component systems were able to accrete gas and small galaxies until later times, boosting their central densities, building up their outer parts, and lowering their typical central ages. In contrast, the oldest galaxies, perhaps due to residing in richer environments, have no remaining hints of their last accretion episode.

  7. Colour gradients of high-redshift early-type galaxies from hydrodynamical monolithic models

    Science.gov (United States)

    Tortora, C.; Pipino, A.; D'Ercole, A.; Napolitano, N. R.; Matteucci, F.

    2013-10-01

    We analyse the evolution of colour gradients predicted by the hydrodynamical models of early-type galaxies (ETGs) in Pipino et al., which reproduce fairly well the chemical abundance pattern and the metallicity gradients of local ETGs. We convert the star formation (SF) and metal content into colours by means of stellar population synthetic model and investigate the role of different physical ingredients, as the initial gas distribution and content, and ɛSF, i.e. the normalization of SF rate. From the comparison with high-redshift data, a full agreement with optical rest-frame observations at z ≲ 1 is found, for models with low ɛSF, whereas some discrepancies emerge at 1 < z < 2, despite our models reproduce quite well the data scatter at these redshifts. To reconcile the prediction of these high ɛSF systems with the shallower colour gradients observed at lower z we suggest intervention of one to two dry mergers. We suggest that future studies should explore the impact of wet galaxy merging, interactions with environment, dust content and a variation of the initial mass function from the galactic centres to the peripheries.

  8. Systematic Variation of Central Mass Density Slope in Early-Type Galaxies

    Science.gov (United States)

    Tortora, C.; La Barbera, F.; Napolitano, N. R.; Romanowsky, A. J.; Ferreras, I.; de Carvalho, R. R.

    We study the total density distribution in the central regions (≲ 1 effective radius, R e) of early-type galaxies (ETGs), using data from the SPIDER survey (La Barbera et al., MNRAS 408:1313, 2010). We model each galaxy with two components (dark matter halo + stars), exploring different assumptions for the dark matter (DM) halo profile, and leaving stellar mass-to-light (M ⋆/L) ratios as free fitting parameters to the data. For a Navarro et al. (ApJ 462:563, 1996) profile, the slope of the total mass profile is non-universal. For the most massive and largest ETGs, the profile is isothermal in the central regions (˜ Re/2), while for the low-mass and smallest systems, the profile is steeper than isothermal, with slopes similar to those for a constant-M/L profile. For a concentration-mass relation steeper than that expected from simulations, the correlation of density slope with mass tends to flatten. Our results clearly point to a "non-homology" in the total mass distribution of ETGs, which simulations of galaxy formation suggest may be related to a varying role of dissipation with galaxy mass.

  9. MOND and IMF variations in early-type galaxies from ATLAS3D

    Science.gov (United States)

    Tortora, C.; Romanowsky, A. J.; Cardone, V. F.; Napolitano, N. R.; Jetzer, Ph.

    2014-02-01

    Modified Newtonian Dynamics (MOND) represents a phenomenological alternative to dark matter (DM) for the missing mass problem in galaxies and clusters of galaxies. We analyse the central regions of a local sample of ˜220 early-type galaxies from the ATLAS3D survey, to see if the data can be reproduced without recourse to DM. We estimate dynamical masses in the MOND context through Jeans analysis and compare to ATLAS3D stellar masses from stellar population synthesis. We find that the observed stellar mass-velocity dispersion relation is steeper than expected assuming MOND with a fixed stellar initial mass function (IMF) and a standard value for the acceleration parameter a0. Turning from the space of observables to model space (a) fixing the IMF, a universal value for a0 cannot be fitted, while, (b) fixing a0 and leaving the IMF free to vary, we find that it is `lighter' (Chabrier like) for low-dispersion galaxies and `heavier' (Salpeter like) for high dispersions. This MOND-based trend matches inferences from Newtonian dynamics with DM and from the detailed analysis of spectral absorption lines, adding to the converging lines of evidence for a systematically varying IMF.

  10. THE NEAR-ULTRAVIOLET LUMINOSITY FUNCTION OF YOUNG, EARLY M-TYPE DWARF STARS

    Energy Technology Data Exchange (ETDEWEB)

    Ansdell, Megan; Baranec, Christoph [Institute for Astronomy, University of Hawaii, Honolulu, HI 96822 (United States); Gaidos, Eric [Department of Geology and Geophysics, University of Hawaii, Honolulu, HI 96822 (United States); Mann, Andrew W. [Department of Astronomy, University of Texas at Austin, Austin, TX 78712 (United States); Lépine, Sebastien [Department of Physics and Astronomy, Georgia State University, Atlanta, GA 30302 (United States); James, David [Cerro Tololo Inter-American Observatory, Casilla 603 La Serena (Chile); Buccino, Andrea; Mauas, Pablo; Petrucci, Romina [Instituto de Astronomía y Física del Espacio, C1428EHA Buenos Aires (Argentina); Law, Nicholas M. [Department of Physics and Astronomy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 (United States); Riddle, Reed [Division of Physics, Mathematics, and Astronomy, California Institute of Technology, Pasadena, CA 91125 (United States)

    2015-01-01

    Planets orbiting within the close-in habitable zones of M dwarf stars will be exposed to elevated high-energy radiation driven by strong magnetohydrodynamic dynamos during stellar youth. Near-ultraviolet (NUV) irradiation can erode and alter the chemistry of planetary atmospheres, and a quantitative description of the evolution of NUV emission from M dwarfs is needed when modeling these effects. We investigated the NUV luminosity evolution of early M-type dwarfs by cross-correlating the Lépine and Gaidos catalog of bright M dwarfs with the Galaxy Evolution Explorer (GALEX) catalog of NUV (1771-2831 Å) sources. Of the 4805 sources with GALEX counterparts, 797 have NUV emission significantly (>2.5σ) in excess of an empirical basal level. We inspected these candidate active stars using visible-wavelength spectra, high-resolution adaptive optics imaging, time-series photometry, and literature searches to identify cases where the elevated NUV emission is due to unresolved background sources or stellar companions; we estimated the overall occurrence of these ''false positives'' (FPs) as ∼16%. We constructed an NUV luminosity function that accounted for FPs, detection biases of the source catalogs, and GALEX upper limits. We found the NUV luminosity function to be inconsistent with predictions from a constant star-formation rate and simplified age-activity relation defined by a two-parameter power law.

  11. Early observations of the nearby type Ia supernova SN 2015F

    CERN Document Server

    Cartier, R; Firth, R; Pignata, G; Mazzali, P; Maguire, K; Childress, M J; Arcavi, I; Ashall, C; Frohmaier, C; Galbany, L; Gal-Yam, A; Hosseinzadeh, G; Howell, D A; Johansson, J; McCully, C; Prajs, S; Prentice, S; Schulze, S; Smartt, S J; Smith, K W; Smith, M; Valenti, S; Young, D R

    2016-01-01

    We present photometry and time-series spectroscopy of the nearby type Ia supernova (SN Ia) SN 2015F over $-16$ days to $+80$ days relative to maximum light, obtained as part of the Public ESO Spectroscopic Survey of Transient Objects (PESSTO). SN 2015F is a slightly sub-luminous SN Ia with a decline rate of $\\Delta m15(B)=1.35 \\pm 0.03$ mag, placing it in the region between normal and SN 1991bg-like events. Our densely-sampled photometric data place tight constraints on the epoch of first light and form of the early-time light curve. The spectra exhibit photospheric C II $\\lambda 6580$ absorption until $-4$ days, and high-velocity Ca II is particularly strong at $14000$ km s$^{-1}$, suggesting mixing in the outermost layers of the SN ejecta. Although unusual in SN Ia spectra, including V II in the modelling significantly improves the spectral fits. Intriguingly, we detect an absorption feature at $\\sim$6800 \\AA\\ that persists until maximum light. Our favoured explanation for this line is photospheric Al II, w...

  12. Inventorying the stellar initial mass function of early-type galaxies

    CERN Document Server

    Tortora, Crescenzo; Napolitano, Nicola R

    2012-01-01

    Given a flurry of recent claims for systematic variations in the stellar initial mass function (IMF), we carry out a novel inventory of the observational evidence using different approaches. This includes literature results, as well as our own new findings from combined stellar-populations synthesis (SPS) and Jeans dynamical analyses of data on ~4500 early-type galaxies from the SPIDER project. We focus on the mass-to-light ratio mismatch relative to the Milky Way IMF, delta_IMF, correlated against the central stellar velocity dispersion, sigma_*. For the SPIDER sample, we find a strong correlation between delta_IMF and sigma_*, independently of assumptions on the dark matter (DM) profile. The overall normalization of delta_IMF, and the detailed DM profile, are less certain, but the data are consistent with standard cold-DM halos, and a central DM fraction that is roughly constant with sigma_*. For a variety of related studies in the literature, using SPS, dynamics, and gravitational lensing, similar results ...

  13. Self-Similar Models for the Mass Profiles of Early-type Lens Galaxies

    CERN Document Server

    Rusin, D; Keeton, C R

    2003-01-01

    We introduce a self-similar mass model for early-type galaxies, and constrain it using the aperture mass-radius relations determined from the geometries of 22 gravitational lenses. The model consists of two components: a concentrated component which traces the light distribution, and a more extended power-law component (rho propto r^-n) which represents the dark matter. We find that lens galaxies have total mass profiles which are nearly isothermal, or slightly steeper, on the several-kiloparsec radial scale spanned by the lensed images. In the limit of a single-component, power-law radial profile, the model implies n=2.07+/-0.13, consistent with isothermal (n=2). Models in which mass traces light are excluded at >99 percent confidence. An n=1 cusp (such as the Navarro-Frenk-White profile) requires a projected dark matter mass fraction of f_cdm = 0.22+/-0.10 inside 2 effective radii. These are the best statistical constraints yet obtained on the mass profiles of lenses, and provide clear evidence for a small ...

  14. IFU spectroscopy of 10 early-type galactic nuclei - III. Properties of the circumnuclear gas emission

    CERN Document Server

    Ricci, T V; Menezes, R B

    2015-01-01

    Many Early-type galaxies (ETG) have ionized gas emission in their centres that extends to scales of ~ 1kpc. The majority of such objects are classified as LINERs, but the nature of their ionizing source is still not clear. The kinematics associated with these gaseous structures usually shows deviations from a pure rotational motion due to non-gravitational effects or to non-axisymmetric potentials. This is the third of a series of papers that describes a sample of 10 nearby and massive ETG observed with the Gemini Multi-Object Spectrograph in Integral Field mode installed on the Gemini-South telescope. In paper II, we performed spectral synthesis to subtract the stellar components from the data cubes of the sample galaxies in order to study their nuclear spectra. Here, we analyse the circumnuclear gas emission (scales of ~ 100 pc) of the sample galaxies. Circumnuclear gas emission was detected in seven galaxies, all of them classified as LINERs. Pure gaseous discs are found in three galaxies. In two objects, ...

  15. The Atlas3D project -- XXXI. Nuclear radio emission in nearby early-type galaxies

    CERN Document Server

    Nyland, Kristina; Wrobel, Joan M; Sarzi, Marc; Morganti, Raffaella; Alatalo, Katherine; Blitz, Leo; Bournaud, Frederic; Bureau, Martin; Cappellari, Michele; Crocker, Alison F; Davies, Roger L; Davis, Timothy A; de Zeeuw, P T; Duc, Pierre-Alain; Emsellem, Eric; Khochfar, Sadegh; Krajnovic, Davor; Kuntschner, Harald; McDermid, Richard M; Naab, Thorsten; Oosterloo, Tom; Scott, Nicholas; Serra, Paolo; Weijmans, Anne-Marie

    2016-01-01

    We present the results of a high-resolution, 5 GHz, Karl G. Jansky Very Large Array study of the nuclear radio emission in a representative subset of the Atlas3D survey of early-type galaxies (ETGs). We find that 51 +/- 4% of the ETGs in our sample contain nuclear radio emission with luminosities as low as 10^18 W/Hz. Most of the nuclear radio sources have compact (< 25-110 pc) morphologies, although < 10% display multi-component core+jet or extended jet/lobe structures. Based on the radio continuum properties, as well as optical emission line diagnostics and the nuclear X-ray properties, we conclude that the majority of the central 5 GHz sources detected in the Atlas3D galaxies are associated with the presence of an active galactic nucleus (AGN). However, even at sub-arcsecond spatial resolution, the nuclear radio emission in some cases appears to arise from low-level nuclear star formation rather than an AGN, particularly when molecular gas and a young central stellar population is present. This is in...

  16. Evidence of boosted 13CO/12CO ratio in early-type galaxies in dense environments

    CERN Document Server

    Alatalo, Katherine; Aalto, Susanne; Davis, Timothy A; Nyland, Kristina; Bureau, Martin; Duc, Pierre-Alain; Krajnovic, Davor; Young, Lisa M

    2015-01-01

    We present observations of $^{13}$CO(1-0) in 17 Combined Array for Research in Millimeter Astronomy (CARMA) Atlas3D early-type galaxies (ETGs), obtained simultaneously with $^{12}$CO(1-0) observations. The $^{13}$CO in six ETGs is sufficiently bright to create images. In these 6 sources, we do not detect any significant radial gradient in the $^{13}$CO/$^{12}$CO ratio between the nucleus and the outlying molecular gas. Using the $^{12}$CO channel maps as 3D masks to stack the $^{13}$CO emission, we are able to detect 15/17 galaxies to $>3\\sigma$ (and 12/17 to at least 5$\\sigma$) significance in a spatially integrated manner. Overall, ETGs show a wide distribution of $^{13}$CO/$^{12}$CO ratios, but Virgo cluster and group galaxies preferentially show a $^{13}$CO/$^{12}$CO ratio about 2 times larger than field galaxies, although this could also be due to a mass dependence, or the CO spatial extent ($R_{\\rm CO}/R_{\\rm e}$). ETGs whose gas has a morphologically-settled appearance also show boosted $^{13}$CO/$^{12...

  17. Early renal failure after domino liver transplantation using organs from donors with primary hyperoxaluria type 1.

    Science.gov (United States)

    Saner, Fuat H; Treckmann, Juergen; Pratschke, Johann; Arbogast, Helmut; Rahmel, Axel; Vester, Udo; Paul, Andreas

    2010-10-15

    Organ shortage is responsible for high mortality rates of patients awaiting liver transplantation (LT). Domino transplantation has had reported success in patients with metabolic disorders. Primary hyperoxaluria type 1 (PH1) is a rare metabolic disorder. There are a few case reports that suggest that PH1 livers originating from donors that have undergone combined liver-kidney transplantation can be successfully used for domino transplantation. In the last decade, five patients received a domino liver transplant from patients with PH1 in the EUROTRANSPLANT region. In this study, we report the clinical course and outcome of these five patients who were received a domino graft transplant. All patients, with the exception of one, suffered from multifocal hepatocellular carcinoma and underwent domino LT from patients undergoing combined liver-kidney transplantation for PH1. Within the first 4 weeks, all the domino recipients developed dialysis-dependent kidney failure despite good liver function. Four of the five patients died. The only survivor underwent retransplantation due to hepatic artery thrombosis. Twenty months after transplantation, this patient is doing well and has had no recurrence of hepatocellular carcinoma. Domino LT using donors with PH1 results in early renal failure and cannot be recommended for transplantation unless preventive strategies have been identified.

  18. Where do "red and dead" early-type void galaxies come from?

    CERN Document Server

    Croton, Darren J

    2008-01-01

    Void regions of the Universe offer a special environment for studying cosmology and galaxy formation, which may expose weaknesses in our understanding of these phenomena. Although galaxies in voids are observed to be predominately gas rich, star forming and blue, a sub-population of bright red void galaxies can also be found, whose star formation was shut down long ago. Are the same processes that quench star formation in denser regions of the Universe also at work in voids? We compare the luminosity function of void galaxies in the 2dFGRS, to those from a galaxy formation model built on the Millennium Simulation. We show that a global star formation suppression mechanism in the form of low luminosity "radio mode" AGN heating is sufficient to reproduce the observed population of void early-types. Radio mode heating is environment independent other than its dependence on dark matter halo mass, where, above a critical mass threshold of approximately Mvir~10^12.5Msun, gas cooling onto the galaxy is suppressed an...

  19. AGN-driven quenching of star formation: morphological and dynamical implications for early-type galaxies

    CERN Document Server

    Dubois, Yohan; Peirani, Sébastien; Silk, Joseph

    2013-01-01

    In order to understand the physical mechanisms at work during the formation of massive early-type galaxies, we performed six zoomed hydrodynamical cosmological simulations of halos in the mass range 4.3 10^12 < M_vir < 8.0 10^13 M_sun at z=0, using the Adaptive Mesh Refinement code RAMSES. These simulations explore the role of Active Galactic Nuclei (AGN), through jets powered by the accretion onto supermassive black holes on the formation of massive elliptical galaxies. In the absence of AGN feedback, large amounts of stars accumulate in the central galaxies to form overly massive, blue, compact and rotation-dominated galaxies. Powerful AGN jets transform the central galaxies into red extended and dispersion-dominated galaxies. This morphological transformation of disc galaxies into elliptical galaxies is driven by the efficient quenching of the in situ star formation due to AGN feedback, which transform these galaxies into systems built up by accretion. For galaxies mainly formed by accretion, the pro...

  20. Investigating the merger origin of Early-Type Galaxies using ultra-deep optical images

    CERN Document Server

    Duc, P -A; Alatalo, K; Blitz, L; Bois, M; Bournaud, F; Bureau, M; Cappellari, M; Cote, P; Davies, R L; Davis, T A; de Zeeuw, P T; Emsellem, E; Ferrarese, L; Ferriere, E; Gwyn, S; Khochfar, S; Krajnovic, D; Kuntschner, H; Lablanche, P -Y; MacArthur, L; McDermid, R M; Michel-Dansac, L; Morganti, R; Naab, T; Oosterloo, T; Sarzi, M; Scott, N; Serra, P; Weijmans, A; Young, L M

    2011-01-01

    The mass assembly of galaxies leaves various imprints on their surroundings, such as shells, streams and tidal tails. The frequency and properties of these fine structures depend on the mechanism driving the mass assembly: e.g. a monolithic collapse, rapid cold-gas accretion followed by violent disk instabilities, minor mergers or major dry / wet mergers. Therefore, by studying the outskirts of galaxies, one can learn about their main formation mechanism. I present here our on-going work to characterize the outskirts of Early-Type Galaxies (ETGs), which are powerful probes at low redshift of the hierarchical mass assembly of galaxies. This work relies on ultra-deep optical images obtained at CFHT with the wide-field of view MegaCam camera of field and cluster ETGs obtained as part of the Atlas-3D and NGVS projects. State of the art numerical simulations are used to interpret the data. The images reveal a wealth of unknown faint structures at levels as faint as 29 mag arcsec-2 in the g-band. Initial results fo...

  1. The Herschel Virgo Cluster Survey - XIII. Dust in Early-Type Galaxies

    CERN Document Server

    Alighieri, Sperello di Serego; Pappalardo, Cirino; Zibetti, Stefano; Auld, Robbie; Baes, Maarten; Bendo, George; Corbelli, Edvige; Davies, Jonathan; Davis, Timothy; De Looze, Ilse; Fritz, Jacopo; Gavazzi, Giuseppe; Giovanardi, Carlo; Grossi, Marco; Hunt, Leslie; Magrini, Laura; Pierini, Daniele; Xilouris, Manolis

    2013-01-01

    Aims. We study the dust content of a large optical input sample of 910 early-type galaxies (ETG) in the Virgo cluster, extending also to the dwarf ETG, and examine the results in relation with those on the other cold ISM components. Methods. We have searched for far-infrared emission in all galaxies of the input sample using the 250 micron image of the Herschel Virgo Cluster Survey, covering a large fraction of the cluster. For the detected ETG we have measured fluxes in 5 bands from 100 to 500 micron, and have estimated the dust mass and temperature with modified black-body fits. Results. Dust is detected above the completeness limit of 25.4 mJy at 250 micron in 46 ETG, 43 of which are in the optically complete part of the input sample. In addition dust is present at fainter levels in another 6 ETG. We detect dust in the 4 ETG with synchrotron emission, including M 87. Dust appears to be much more concentrated than stars and more luminous ETG have higher dust temperatures. Dust detection rates down to the 25...

  2. Depleted cores, multi-component fits, and structural parameter relations for luminous early-type galaxies

    CERN Document Server

    Dullo, Bililign T

    2013-01-01

    New surface brightness profiles from 26 early-type galaxies with partially depleted cores have been extracted from the full radial extent of Hubble Space Telescope images, giving us a total sample of 31 such core-Sersic galaxies. We have carefully quantified the radial stellar distributions of the elliptical galaxies using the core-Sersic model whereas for the lenticular galaxies a core-Sersic bulge plus an exponential disc model gives the best representation. We additionally caution about the excessive use of multiple Sersic functions for decomposing galaxies. The structural parameters obtained from our fitted models are used to update several `central' as well as `global' galaxy scaling relations. We find near-linear relations between the break radius R_b and the spheroid luminosity L such that R_b ~ L^(1.13 +/- 0.13), and with the supermassive black hole mass M_BH such that R_b ~ M_BH^(0.83+/- 0.21). This is internally consistent with the notion that major, dry mergers add the stellar and black hole mass i...

  3. IFU spectroscopy of 10 early type galactic nuclei: II - Nuclear emission line properties

    CERN Document Server

    Ricci, T V; Menezes, R B

    2014-01-01

    Although it is well known that massive galaxies have central black holes, most of them accreting at low Eddington ratios, many important questions still remain open. Among them, are the nature of the ionizing source, the characteristics and frequencies of the broad line region and of the dusty torus. We report observations of 10 early-type galactic nuclei, observed with the IFU/GMOS spectrograph on the Gemini South telescope, analysed with standard techniques for spectral treatment and compared with results obtained with principal component analysis Tomography (Paper I). We performed spectral synthesis of each spaxel of the data cubes and subtracted the stellar component from the original cube, leaving a data cube with emission lines only. The emission lines were decomposed in multi-Gaussian components. We show here that, for eight galaxies previously known to have emission lines, the narrow line region can be decomposed in two components with distinct line widths. In addition to this, broad H$\\alpha$ emissio...

  4. Formation and evolution of dwarf early-type galaxies in the Virgo cluster I. Internal kinematics

    CERN Document Server

    Toloba, E; Cenarro, A J; Peletier, R F; Gorgas, J; de Paz, A Gil; Munoz-Mateos, J C

    2010-01-01

    We present new medium resolution kinematic data for a sample of 21 dwarf early-type galaxies (dEs) mainly in the Virgo cluster, obtained with the WHT and INT telescopes at the Roque de los Muchachos Observatory (La Palma, Spain). These data are used to study the origin of the dwarf elliptical galaxy population inhabiting clusters. We confirm that dEs are not dark matter dominated galaxies, at least up to the half-light radius. We also find that the observed galaxies in the outer parts of the cluster are mostly rotationally supported systems with disky morphological shapes. Rotationally supported dEs have rotation curves similar to those of star forming galaxies of similar luminosity and follow the Tully-Fisher relation. This is expected if dE galaxies are the descendant of low luminosity star forming systems which recently entered the cluster environment and lost their gas due to a ram pressure stripping event, quenching their star formation activity and transforming into quiescent systems, but conserving the...

  5. Mid- to Far-IR Emission and Star Formation in Early-Type Galaxies

    CERN Document Server

    Young, L M; Lucero, Danielle

    2008-01-01

    Many early-type galaxies have been detected at wavelengths of 24 to 160 micron, but the emission is usually dominated by heating from an AGN or from the evolved stellar population. Here we present Spitzer MIPS observations of a sample of elliptical and lenticular galaxies that are rich in cold molecular gas, and we investigate whether the MIR to FIR emission could be associated with star formation activity. The 24 micron images show a rich variety of structures, including nuclear point sources, rings, disks, and smooth extended emission. Comparisons to matched-resolution CO and radio continuum images suggest that the bulk of the 24 micron emission can be traced to star formation with some notable exceptions. The 24 micron luminosities of the CO-rich galaxies are typically a factor of 15 larger than what would be expected from the dust associated with their evolved stars. In addition, FIR/radio flux density ratios are consistent with star formation. We conclude that the star formation rates in z=0 elliptical a...

  6. The Near-Ultraviolet Luminosity Function of Young, Early M-Type Dwarf Stars

    CERN Document Server

    Ansdell, Megan; Mann, Andrew W; Lepine, Sebastien; James, David; Buccino, Andrea; Baranec, Christoph; Law, Nicholas M; Riddle, Reed; Mauas, Pablo; Petrucci, Romina

    2014-01-01

    Planets orbiting within the close-in habitable zones of M dwarf stars will be exposed to elevated high-energy radiation driven by strong magneto-hydrodynamic dynamos during stellar youth. Near-ultraviolet (NUV) irradiation can erode and alter the chemistry of planetary atmospheres, and a quantitative description of the evolution of NUV emission from M dwarfs is needed when modeling these effects. We investigated the NUV luminosity evolution of early M-type dwarfs by cross-correlating the Lepine & Gaidos (2011) catalog of bright M dwarfs with the GALEX catalog of NUV (1771-2831A) sources. Of the 4805 sources with GALEX counterparts, 797 have NUV emission significantly (> 2.5 sigma) in excess of an empirical basal level. We inspected these candidate active stars using visible-wavelength spectra, high-resolution adaptive optics imaging, time-series photometry, and literature searches to identify cases where the elevated NUV emission is due to unresolved background sources or stellar companions; we estimated ...

  7. Kinematics of gas and stars in circumnuclear star-forming regions of early type spirals

    CERN Document Server

    Hagele, Guillermo F; Cardaci, Monica V; Terlevich, Elena; Terlevich, Roberto

    2008-01-01

    (Abbr.) We present high resolution (R~20000) spectra in the blue and the far red of cicumnuclear star-forming regions (CNSFRs) in three early type spirals (NGC3351, NGC2903 and NGC3310) which have allowed the study of the kinematics of stars and ionized gas in these structures and, for the first time, the derivation of their dynamical masses for the first two. In some cases these regions, about 100 to 150 pc in size, are seen to be composed of several individual star clusters with sizes between 1.5 and 4.9 pc estimated from Hubble Space Telescope (HST) images. The stellar dispersions have been obtained from the Calcium triplet (CaT) lines at $\\lambda\\lambda$ 8494,8542,8662 \\AA, while the gas velocity dispersions have been measured by Gaussian fits to the H$\\beta$ and [OIII] $\\lambda\\lambda$ 5007 \\AA lines on the high dispersion spectra. Values of the stellar velocity dispersions are between 30 and 68 km/s. We apply the virial theorem to estimate dynamical masses of the clusters, assuming that systems are grav...

  8. Group, field and isolated early-type galaxies II. Global trends from nuclear data

    CERN Document Server

    Denicolo, G; Terlevich, E; Forbes, D A; Terlevich, A I; Denicolo, Glenda; Terlevich, Roberto; Terlevich, Elena; Forbes, Duncan A.; Terlevich, Alejandro

    2004-01-01

    We have derived ages, metallicities and enhanced-element ratios [alpha/Fe] for a sample of 83 early-type galaxies essentially in groups, the field or isolated objects. The stellar population properties derived for each galaxy corresponds to the nuclear r_e/8 aperture extraction. The median age found for Es is 5.8 +- 0.6 Gyr and the average metallicity is +0.37 +- 0.03 dex. For S0s, the median age is 3.0 +- 0.6 Gyr and [Z/H] = 0.53 +- 0.04 dex. We compare the distribution of our galaxies in the Hbeta-[MgFe] diagram with Fornax galaxies. Our elliptical galaxies are 3-4 Gyr younger than Es in the Fornax cluster. We find that the galaxies lie in a plane defined by [Z/H] = 0.99 log sigma_0 - 0.46 log Age - 1.60. More massive (larger sigma_0) and older galaxies present, on average, large [alpha/Fe] values, and therefore, must have undergone shorter star-formation timescales. Comparing group against field/isolated galaxies, it is not clear that environment plays an important role in determining their stellar populat...

  9. Properties of the ionized gas of circumnuclear star-forming regions in early type spirals

    CERN Document Server

    Diaz, Angeles I; Terlevich, Elena; Terlevich, Roberto

    2008-01-01

    (Abbr.) A study of cicumnuclear star-forming regions (CNSFRs) in several early type spirals has been made in order to investigate their main properties: stellar and gas kinematics, dynamical masses, ionising stellar masses, chemical abundances and other properties of the ionised gas. Both high resolution (R$ \\sim $20000) and moderate resolution (R ~ 5000) have been used. In some cases these regions, about 100 to 150 pc in size, are seen to be composed of several individual star clusters with sizes between 1.5 and 4.9 pc estimated from Hubble Space Telescope (HST) images. Stellar and gas velocity dispersions are found to differ by about 20 to 30 km/s with the H$\\beta$ emission lines being narrower than both the stellar lines and the [OIII] $\\lambda$ 5007 \\AA lines. The twice ionized oxygen, on the other hand, shows velocity dispersions comparable to those shown by stars. We have applied the virial theorem to estimate dynamical masses of the clusters, assuming that systems are gravitationally bounded and spheri...

  10. Galaxy Zoo: Dust and molecular gas in early-type galaxies with prominent dust lanes

    CERN Document Server

    Kaviraj, Sugata; Bureau, Martin; Shabala, Stanislav S; Crockett, R Mark; Silk, Joseph; Lintott, Chris; Smith, Arfon; Keel, William C; Masters, Karen L; Schawinski, Kevin; Bamford, Steven P

    2011-01-01

    We study dust and associated molecular gas in 352 nearby early-type galaxies (ETGs) with prominent dust lanes. 65% of these 'dusty ETGs' (D-ETGs) are morphologically disturbed, suggesting a merger origin. This is consistent with the D-ETGs residing in lower-density environments compared to a control sample drawn from the general ETG population. 80% of D-ETGs inhabit the field (compared to 60% of the controls) and <2% inhabit clusters (compared to 10% of the controls). Compared to the control sample, D-ETGs exhibit bluer UV-optical colours (indicating enhanced star formation) and an AGN fraction that is more than an order of magnitude greater. The clumpy dust mass residing in large-scale features is estimated, using the SDSS r-band images, to be between 10^{4.5} and 10^{6.5} MSun. Comparison to the total (clumpy + diffuse) dust masses - calculated using far-infrared fluxes of the 15% of the D-ETGs that are detected by IRAS - indicates that only ~20% of the dust resides in these large-scale features. The dus...

  11. Globular Cluster Systems of Early-type Galaxies in Low-density Environments

    CERN Document Server

    Cho, J; Blakeslee, J P; Zepf, S E; Kundu, A; Kim, H -S; Yoon, S -J

    2012-01-01

    Deep images of 10 early-type galaxies in low-density environments have been obtained with the Advanced Camera for Surveys (ACS) on the Hubble Space Telescope. The global properties of the globular cluster (GC) systems of the galaxies have been derived in order to investigate the role of the environment in galaxy formation and evolution. Using the ACS Virgo Cluster Survey (ACSVCS) as a high-density counterpart, the similarities and differences between the GC properties in high- and low-density environments are presented. We find a strong correlation of the GC mean colours and the degree of colour bimodality with the host galaxy luminosity in low-density environments, in good agreement with high-density environments. In contrast, the GC mean colours at a given host luminosity are somewhat bluer (\\Delta(g-z) ~ 0.05) than those for cluster galaxies, indicating more metal-poor (\\Delta[Fe/H] ~ 0.10-0.15) and/or younger (\\Delta age > 2 Gyr) GC systems than those in dense environments. Furthermore, with decreasing ho...

  12. Cosmic Evolution of Size and Velocity Dispersion for Early Type Galaxies

    CERN Document Server

    Fan, L; Bressan, A; Bernardi, M; De Zotti, G; Danese, L

    2010-01-01

    [abridged] Massive, passively evolving galaxies at redshifts z>1 exhibit on the average physical sizes smaller by factors ~3 than local early type galaxies (ETGs) endowed with the same stellar mass. Small sizes are in fact expected on theoretical grounds, if dissipative collapse occurs. Recent results show that the size evolution at z1, where both compact and already extended galaxies are observed and the scatter in size is remarkably larger than locally. The presence at high z of a significant number of ETGs with the same size as their local counterparts as well as of ETGs with quite small size, points to a timescale to reach the new, expanded equilibrium configuration of less than the Hubble time. We demonstrate that the projected mass of compact, high-z galaxies and that of local ETGs within the *same physical radius*, the nominal half-luminosity radius of high-z ETGs, differ substantially, in that the high-z ETGs are on the average significantly denser. We propose that quasar activity, which peaks at z~2,...

  13. Puffing up early-type galaxies by baryonic mass loss: numerical experiments

    CERN Document Server

    Ragone-Figueroa, Cinthia

    2011-01-01

    We present numerical simulations of the effect of baryonic mass loss on the structure of a spheroidal stellar system, embedded in a dark matter halo. This process could be caused either by QSO/starburst driven galactic winds, promptly ejecting from Early Type Galaxies (ETGs) the residual gas (galactic winds), or by stellar mass returned to the ISM in the final stages of stellar evolution. We find that a conceivable loss of about 50% of the baryonic mass can produce a significant size increase, which could contribute to the claimed size evolution of ETGs since z about 2. However, most (all in the case of QSO driven winds) of the puffing up occurs when the stellar population are much younger than the estimated ages of compact high-z ETGs. We conclude that the putative expansion caused by galactic winds is still not observed, while that due to stellar evolution could contribute to, but not dominate, the evolution of the mass-size relationship of ETGs observed so far.

  14. The early life origin theory in the development of cardiovascular disease and type 2 diabetes.

    Science.gov (United States)

    Lindblom, Runa; Ververis, Katherine; Tortorella, Stephanie M; Karagiannis, Tom C

    2015-04-01

    Life expectancy has been examined from a variety of perspectives in recent history. Epidemiology is one perspective which examines causes of morbidity and mortality at the population level. Over the past few 100 years there have been dramatic shifts in the major causes of death and expected life length. This change has suffered from inconsistency across time and space with vast inequalities observed between population groups. In current focus is the challenge of rising non-communicable diseases (NCD), such as cardiovascular disease and type 2 diabetes mellitus. In the search to discover methods to combat the rising incidence of these diseases, a number of new theories on the development of morbidity have arisen. A pertinent example is the hypothesis published by David Barker in 1995 which postulates the prenatal and early developmental origin of adult onset disease, and highlights the importance of the maternal environment. This theory has been subject to criticism however it has gradually gained acceptance. In addition, the relatively new field of epigenetics is contributing evidence in support of the theory. This review aims to explore the implication and limitations of the developmental origin hypothesis, via an historical perspective, in order to enhance understanding of the increasing incidence of NCDs, and facilitate an improvement in planning public health policy.

  15. Molecular gas and nuclear activity in early-type galaxies: any link with radio-loudness?

    CERN Document Server

    Baldi, Ranieri D; Capetti, Alessandro; Giovannini, Gabriele; Casasola, Viviana; Perez-Torres, Miguel A; Kuno, Nario

    2014-01-01

    Aims. We want to study the amount of molecular gas in a sample of nearby early-type galaxies (ETGs) which host low-luminosity Active Galactic Nuclei (AGN). We look for possible differences between the radio-loud (RL) and radio-quiet (RQ) AGN. Methods. We observed the CO(1-0) and CO(2-1) spectral lines with the IRAM 30m and NRO 45m telescopes for eight galaxies. They belong to a large sample of 37 local ETGs which host both RQ and RL AGN. We gather data from the literature for the entire sample. Results. We report the new detection of CO(1-0) emission in four galaxies (UGC0968, UGC5617, UGC6946, and UGC8355) and CO(2-1) emission in two of them (UGC0968 and UGC5617). The CO(2-1)/CO(1-0) ratio in these sources is $\\sim0.7\\pm0.2$. Considering both the new observations and the literature, the detection rate of CO in our sample is 55 $\\pm$ 9%, with no statistically significant difference between the hosts of RL and RQ AGNs. For all the detected galaxies we converted the CO luminosities into the molecular masses, $M...

  16. Aneuploidy involving chromosome 1 may be an early predictive marker of intestinal type gastric cancer

    Energy Technology Data Exchange (ETDEWEB)

    Williams, L. [Royal Glamorgan Hospital, Ynysmaerdy, Llantrisant CF72 8XR (United Kingdom); Somasekar, A. [Institute of Life Science, Swansea School of Medicine, Swansea University, Swansea SA28PP (United Kingdom); Neath Port Talbot Hospital, Abertawe Bro Morgannwg University NHS Trust, Baglan Way, Port Talbot SA12 7BX (United Kingdom); Davies, D.J.; Cronin, J.; Doak, S.H. [Institute of Life Science, Swansea School of Medicine, Swansea University, Swansea SA28PP (United Kingdom); Alcolado, R. [Royal Glamorgan Hospital, Ynysmaerdy, Llantrisant CF72 8XR (United Kingdom); Williams, J.G. [Neath Port Talbot Hospital, Abertawe Bro Morgannwg University NHS Trust, Baglan Way, Port Talbot SA12 7BX (United Kingdom); Griffiths, A.P. [Department of Histopathology, Morriston Hospital, Abertawe Bro Morgannwg University NHS Trust, Morriston, SA66NL (United Kingdom); Baxter, J.N. [Department of Surgery, Morriston Hospital, Abertawe Bro Morgannwg University NHS Trust, Morriston, SA66NL (United Kingdom); Jenkins, G.J.S., E-mail: g.j.jenkins@swansea.ac.uk [Institute of Life Science, Swansea School of Medicine, Swansea University, Swansea SA28PP (United Kingdom)

    2009-10-02

    Intestinal type gastric cancer is a significant cause of mortality, therefore a better understanding of its molecular basis is required. We assessed if either aneuploidy or activity of the oncogenic transcription factor nuclear factor kappa B (NF-{kappa}B), increased incrementally during pre-malignant gastric histological progression and also if they correlated with each other in patient samples, as they are both induced by oxygen free radicals. In a prospective study of 54 (aneuploidy) and 59 (NF-{kappa}B) consecutive patients, aneuploidy was assessed by interphase fluorescent in situ hybridisation (FISH) for chromosome 1. NF-{kappa}B was assessed by expression of interleukin-8 (IL-8), and in a subset, by immunohistochemistry (IHC) for active p65. Aneuploidy levels increased incrementally across the histological series. 2.76% of cells with normal histology (95% CI, 2.14-3.38%) showed background levels of aneuploidy, this increased to averages of 3.78% (95% CI, 3.21-4.35%), 5.89% (95% CI, 3.72-8.06%) and 7.29% (95% CI, 4.73-9.85%) of cells from patients with gastritis, Helicobacter pylori positive gastritis and atrophy/intestinal metaplasia (IM) respectively. IL-8 expression was only increased in patients with current H. pylori infection. NF-{kappa}B analysis showed some increased p65 activity in inflamed tissues. IL-8 expression and aneuploidy level were not linked in individual patients. Aneuploidy levels increased incrementally during histological progression; were significantly elevated at very early stages of neoplastic progression and could well be linked to cancer development and used to assess cancer risk. Reactive oxygen species (ROS) induced in early gastric cancer are presumably responsible for the stepwise accumulation of this particular mutation, i.e. aneuploidy. Hence, aneuploidy measured by fluorescent in situ hybridisation (FISH) coupled to brush cytology, would be worthy of consideration as a predictive marker in gastric cancer and could be

  17. Preliminary analysis of immune activation in early onset type 2 diabetes

    Directory of Open Access Journals (Sweden)

    Julia D. Rempel

    2013-08-01

    Full Text Available Introduction. First Nations and other Aboriginal children are disproportionately affected by cardiometabolic diseases, including type 2 diabetes (T2D. In T2D, the disruption of insulin signalling can be driven by pro-inflammatory immunity. Pro-inflammatory responses can be fueled by toll-like receptors (TLR on immune cells such as peripheral blood mononuclear cells (PBMC, a white blood cell population. TLR4 can bind to lipids from bacteria and food sources activating PBMC to produce cytokines tumour necrosis factor (TNF-α and interleukin (IL-1β. These cytokines can interfere with insulin signalling. Here, we seek to understand how TLR4 activation may be involved in early onset T2D. We hypothesized that immune cells from youth with T2D (n=8 would be more reactive upon TLR4 stimulation relative to cells from age and body mass index (BMI-matched controls without T2D (n=8. Methods. Serum samples were assayed for adipokines (adiponectin and leptin, as well as cytokines. Freshly isolated PBMC were examined for immune reactivity upon culture with TLR4 ligands bacterial lipopolysaccharide (LPS, 2 and 0.2 ng/ml and the fatty acid palmitate (200 µM. Culture supernatants were evaluated for the amount of TNF-α and IL-1β produced by PBMC. Results. Youth with T2D displayed lower median serum adiponectin levels compared to controls (395 vs. 904 ng/ml, p<0.05. PBMC isolated from youth with and without T2D produced similar levels of TNF-α and IL-1β after exposure to the higher LPS concentration. However, at the low LPS dose the T2D cohort exhibited enhanced IL-1β synthesis relative to the control cohort. Additionally, exposure to palmitate resulted in greater IL-1β synthesis in PBMCs isolated from youth with T2D versus controls (p<0.05. These differences in cytokine production corresponded to greater monocyte activation in the T2D cohort. Conclusion. These preliminary results suggest that cellular immune responses are exaggerated in T2D, particularly

  18. Effects of Type I Collagen Degradation on the Durability of Three Adhesive Systems in the Early Phase of Dentin Bonding

    OpenAIRE

    Lin Hu; Yu-hong Xiao; Ming Fang; Yu Gao; Li Huang; An-qi Jia; Ji-hua Chen

    2015-01-01

    Objective This study was designed to evaluate the effects of type I collagen degradation on the durability of three adhesive systems in the early phase of dentin bonding. Methods Bonded dentin specimens were prepared using three different types of adhesive systems. Micro-tensile bond strength and degradation of collagen were tested before, and after 1 month or 4 months of aging in artificial saliva. The relationship between micro-tensile bond strength and collagen degradation was analyzed by ...

  19. The ATLAS3D project - XIX. The hot gas content of early-type galaxies: fast versus slow rotators

    NARCIS (Netherlands)

    Sarzi, Marc; Alatalo, Katherine; Blitz, Leo; Bois, Maxime; Bournaud, Frédéric; Bureau, Martin; Cappellari, Michele; Crocker, Alison; Davies, Roger L.; Davis, Timothy A.; de Zeeuw, P. T.; Duc, Pierre-Alain; Emsellem, Eric; Khochfar, Sadegh; Krajnović, Davor; Kuntschner, Harald; Lablanche, Pierre-Yves; McDermid, Richard M.; Morganti, Raffaella; Naab, Thorsten; Oosterloo, Tom; Scott, Nicholas; Serra, Paolo; Young, Lisa M.; Weijmans, Anne-Marie

    2013-01-01

    For early-type galaxies, the ability to sustain a corona of hot, X-ray-emitting gas could have played a key role in quenching their star formation history. A halo of hot gas may act as an effective shield against the acquisition of cold gas and can quickly absorb stellar mass loss material. Yet, sin

  20. The ATLAS(3D) project : XIX. The hot gas content of early-type galaxies: fast versus slow rotators

    NARCIS (Netherlands)

    Sarzi, Marc; Alatalo, Katherine; Blitz, Leo; Bois, Maxime; Bournaud, Frederic; Bureau, Martin; Cappellari, Michele; Crocker, Alison; Davies, Roger L.; Davis, Timothy A.; de Zeeuw, P. T.; Duc, Pierre-Alain; Emsellem, Eric; Khochfar, Sadegh; Krajnovic, Davor; Kuntschner, Harald; Lablanche, Pierre-Yves; McDermid, Richard M.; Morganti, Raffaella; Naab, Thorsten; Oosterloo, Tom; Scott, Nicholas; Serra, Paolo; Young, Lisa M.; Weijmans, Anne-Marie

    2013-01-01

    For early-type galaxies, the ability to sustain a corona of hot, X-ray-emitting gas could have played a key role in quenching their star formation history. A halo of hot gas may act as an effective shield against the acquisition of cold gas and can quickly absorb stellar mass loss material. Yet, sin

  1. The ATLAS3D project - XXII. Low-efficiency star formation in early-type galaxies: hydrodynamic models and observations

    CERN Document Server

    Martig, Marie; Bournaud, Frederic; Emsellem, Eric; Gabor, Jared M; Alatalo, Katherine; Blitz, Leo; Bois, Maxime; Bureau, Martin; Cappellari, Michele; Davies, Roger L; Davis, Timothy A; Dekel, Avishai; de Zeeuw, P T; Duc, Pierre-Alain; Falcon-Barroso, Jesus; Khochfar, Sadegh; Krajnovic, Davor; Kuntschner, Harald; Morganti, Raffaella; McDermid, Richard M; Naab, Thorsten; Oosterloo, Tom; Sarzi, Marc; Scott, Nicholas; Serra, Paolo; Griffin, Kristen Shapiro; Teyssier, Romain; Weijmans, Anne-Marie; Young, Lisa M

    2012-01-01

    We study the global efficiency of star formation in high resolution hydrodynamical simulations of gas discs embedded in isolated early-type and spiral galaxies. Despite using a universal local law to form stars in the simulations, we find that the early-type galaxies are offset from the spirals on the large-scale Kennicutt relation, and form stars 2 to 5 times less efficiently. This offset is in agreement with previous results on morphological quenching: gas discs are more stable against star formation when embedded in early-type galaxies due to the lower disc self-gravity and increased shear. As a result, these gas discs do not fragment into dense clumps and do not reach as high densities as in the spiral galaxies. Even if some molecular gas is present, the fraction of very dense gas (above 10^4 cm-3) is significantly reduced, which explains the overall lower star formation efficiency. We also analyse a sample of local early-type and spiral galaxies, measuring their CO and HI surface densities and their star...

  2. The dominant role of mergers in the size evolution of massive early-type galaxies since z similar to 1

    NARCIS (Netherlands)

    López-Sanjuan, C.; Le Fèvre, O.; Ilbert, O.; Tasca, L. A. M.; Bridge, C.; Cucciati, O.; Kampczyk, P.; Pozzetti, L.; Xu, C.K.; Carollo, C. M.; Contini, T.; Kneib, J. -P; Lilly, S. J.; Mainieri, V.; Renzini, A.; Sanders, D.; Scodeggio, M.; Scoville, N. Z.; Taniguchi, Y.; Zamorani, G.; Aussel, H.; Bardelli, S.; Bolzonella, M.; Bongiorno, A.; Capak, P.; Caputi, K.; de la Torre, S.; de Ravel, L.; Franzetti, P.; Garilli, B.; Iovino, A.; Knobel, C.; Kovač, K.; Lamareille, F.; Le Borgne, J. -F; Le Brun, V.; Le Floc'h, E.; Maier, C.; McCracken, H. J.; Mignoli, M.; Pelló, R.; Peng, Y.; Pérez-Montero, E.; Presotto, V.; Ricciardelli, E.; Salvato, M.; Silverman, J. D.; Tanaka, M.; Tresse, L.; Vergani, D.; Zucca, E.; Barnes, L.; Bordoloi, R.; Cappi, A.; Cimatti, A.; Coppa, G.; Koekemoer, A.; Liu, C.T.; Moresco, M.; Nair, P.; Oesch, P.; Schawinski, K.; Welikala, N.

    2012-01-01

    Aims. The role of galaxy mergers in massive galaxy evolution, and in particular to mass assembly and size growth, remains an open question. In this paper we measure the merger fraction and rate, both minor and major, of massive early-type galaxies (M-star >= 10(11) M-circle dot) in the COSMOS field,

  3. The ATLAS3D Project - XXX. Star formation histories and stellar population scaling relations of early-type galaxies

    NARCIS (Netherlands)

    McDermid, Richard M.; Alatalo, Katherine; Blitz, Leo; Bournaud, Frédéric; Bureau, Martin; Cappellari, Michele; Crocker, Alison F.; Davies, Roger L.; Davis, Timothy A.; de Zeeuw, P. T.; Duc, Pierre-Alain; Emsellem, Eric; Khochfar, Sadegh; Krajnović, Davor; Kuntschner, Harald; Morganti, Raffaella; Naab, Thorsten; Oosterloo, Tom; Sarzi, Marc; Scott, Nicholas; Serra, Paolo; Weijmans, Anne-Marie; Young, Lisa M.

    2015-01-01

    We present the stellar population content of early-type galaxies from the ATLAS3D survey. Using spectra integrated within apertures covering up to one effective radius, we apply two methods: one based on measuring line-strength indices and applying single stellar population (SSP) models to derive SS

  4. Evidence for Dark Matter Contraction and a Salpeter Initial Mass Function in a Massive Early-type Galaxy

    NARCIS (Netherlands)

    Sonnenfeld, A.; Treu, T.; Gavazzi, R.; Marshall, P. J.; Auger, M. W.; Suyu, S. H.; Koopmans, L. V. E.; Bolton, A. S.

    2012-01-01

    Stars and dark matter account for most of the mass of early-type galaxies, but uncertainties in the stellar population and the dark matter profile make it challenging to distinguish between the two components. Nevertheless, precise observations of stellar and dark matter are extremely valuable for t

  5. SPIDER - IV. Optical and NIR color gradients in Early-type galaxies: New Insights into Correlations with Galaxy Properties

    CERN Document Server

    La Barbera, F; de la Rosa, I G; Gal, R R; Swindle, R; Lopes, P A A

    2010-01-01

    We present an analysis of stellar population gradients in 4,546 Early-Type Galaxies with photometry in $grizYHJK$ along with optical spectroscopy. A new approach is described which utilizes color information to constrain age and metallicity gradients. Defining an effective color gradient, $\

  6. The sloan lens acs survey. II. Stellar populations and internal structure of early-type lens galaxies

    NARCIS (Netherlands)

    Treu, Tommaso; Koopmans, Léon V.; Bolton, Adam S.; Burles, Scott; Moustakas, Leonidas A.

    2006-01-01

    We use HST images to derive effective radii and effective surface brightnesses of 15 early-type (E+S0) lens galaxies identified by the SLACS Survey. Our measurements are combined with stellar velocity dispersions from the SDSS database to investigate for the first time the distribution of lens galax

  7. The SAURON project - XII. Kinematic substructures in early-type galaxies : evidence for discs in fast rotators

    NARCIS (Netherlands)

    Krajnovic, Davor; Bacon, R.; Cappellari, Michele; Davies, Roger L.; de Zeeuw, P. T.; Emsellem, Eric; Falcon-Barroso, Jesus; Kuntschner, Harald; McDermid, Richard M.; Peletier, Reynier F.; Sarzi, Marc; van den Bosch, Remco C. E.; van de Ven, Glenn

    2008-01-01

    We analysed two-dimensional maps of 48 early-type galaxies obtained with the SAURON and OASIS integral-field spectrographs using kinemetry, a generalization of surface photometry to the higher order moments of the line-of-sight velocity distribution (LOSVD). The maps analysed include: reconstructed

  8. Stellar Populations And Star-formation Histories Of Early-type Galaxies From The Atlas3d Survey

    NARCIS (Netherlands)

    McDermid, Richard; Alatalo, K.; Blitz, L.; Bois, M.; Bournaud, F.; Bureau, M.; Cappellari, M.; Davies, R. L.; Davis, T.; de Zeeuw, T.; Emsellem, E.; Khochfar, S.; Krajnovic, D.; Kuntschner, H.; Lablanche, P.; Morganti, R.; Naab, T.; Oosterloo, T.; Sarzi, M.; Scott, N.; Serra, P.; Weijmans, A.; Young, L.

    2011-01-01

    Atlas3D is a new survey based on integral-field spectroscopy for a complete, volume-limited sample of 260 early-type galaxies observed within the local 40 Mpc volume - the largest survey of its kind. This K-band selected sample spans a range in mass from 10e10 to 10e12 solar masses, and probes two o

  9. Lipidomic and metabolomic characterization of a genetically modified mouse model of the early stages of human type 1 diabetes pathogenesis

    DEFF Research Database (Denmark)

    Overgaard, Anne Julie; Weir, Jacquelyn M; De Souza, David Peter;

    2016-01-01

    The early mechanisms regulating progression towards beta cell failure in type 1 diabetes (T1D) are poorly understood, but it is generally acknowledged that genetic and environmental components are involved. The metabolomic phenotype is sensitive to minor variations in both, and accordingly reflec...

  10. The SAURON project - XV. Modes of star formation in early-type galaxies and the evolution of the red sequence

    NARCIS (Netherlands)

    Shapiro, Kristen L.; Falcón-Barroso, Jesús; van de Ven, Glenn; de Zeeuw, P. Tim; Sarzi, Marc; Bacon, Roland; Bolatto, Alberto; Cappellari, Michele; Croton, Darren; Davies, Roger L.; Emsellem, Eric; Fakhouri, Onsi; Krajnović, Davor; Kuntschner, Harald; McDermid, Richard M.; Peletier, Reynier F.; van den Bosch, Remco C. E.; van der Wolk, Guido

    2010-01-01

    We combine SAURON integral field data of a representative sample of local early-type, red sequence galaxies with Spitzer/Infrared Array Camera imaging in order to investigate the presence of trace star formation in these systems. With the Spitzer data, we identify galaxies hosting low-level star for

  11. The SAURON project : XV. Modes of star formation in early-type galaxies and the evolution of the red sequence

    NARCIS (Netherlands)

    Shapiro, Kristen L.; Falcon-Barroso, Jesus; van de Ven, Glenn; de Zeeuw, P. Tim; Sarzi, Marc; Bacon, Roland; Bolatto, Alberto; Cappellari, Michele; Croton, Darren; Davies, Roger L.; Emsellem, Eric; Fakhouri, Onsi; Krajnovic, Davor; Kuntschner, Harald; McDermid, Richard M.; Peletier, Reynier F.; van den Bosch, Remco C. E.; van der Wolk, Guido

    2010-01-01

    We combine SAURON integral field data of a representative sample of local early-type, red sequence galaxies with Spitzer/Infrared Array Camera imaging in order to investigate the presence of trace star formation in these systems. With the Spitzer data, we identify galaxies hosting low-level star for

  12. The Lenses Structure and Dynamics Survey: luminous and dark matter in high redshift early-type galaxies

    NARCIS (Netherlands)

    Treu, T.; Koopmans, L.

    2003-01-01

    I will present the latest results from the Lenses Structure and Dynamics (LSD) Survey. Using ESI on the Keck Telescope, we have measured spatially resolved stellar kinematics for a sample of 11 early-type galaxies (E/S0s) in the range z=0.1-1, selected as gravitational lenses. By combining lensing a

  13. The ATLAS3D Project - XXX. Star formation histories and stellar population scaling relations of early-type galaxies

    NARCIS (Netherlands)

    McDermid, Richard M.; Alatalo, Katherine; Blitz, Leo; Bournaud, Frédéric; Bureau, Martin; Cappellari, Michele; Crocker, Alison F.; Davies, Roger L.; Davis, Timothy A.; de Zeeuw, P. T.; Duc, Pierre-Alain; Emsellem, Eric; Khochfar, Sadegh; Krajnović, Davor; Kuntschner, Harald; Morganti, Raffaella; Naab, Thorsten; Oosterloo, Tom; Sarzi, Marc; Scott, Nicholas; Serra, Paolo; Weijmans, Anne-Marie; Young, Lisa M.

    We present the stellar population content of early-type galaxies from the ATLAS3D survey. Using spectra integrated within apertures covering up to one effective radius, we apply two methods: one based on measuring line-strength indices and applying single stellar population (SSP) models to derive

  14. The XLENS Project : Do More Massive Early-Type Galaxies Have More Dark Matter or Different Stellar IMFs?

    NARCIS (Netherlands)

    Spiniello, Chiara; Thomas, Daniel; Pasquali, Anna; Ferreras, Ignacio

    The X-shooter Lens Survey (XLENS) aims to study the interplay of dark matter (DM) and stellar content in the inner regions of massive early-type galaxies (ETGs) by combining strong gravitational lensing, dynamical models, and spectroscopic stellar population analysis. XLENS targets a sample of ETGs

  15. The SLUGGS survey: globular clusters and the dark matter content of early-type galaxies

    Science.gov (United States)

    Forbes, Duncan A.; Alabi, Adebusola; Romanowsky, Aaron J.; Brodie, Jean P.; Strader, Jay; Usher, Christopher; Pota, Vincenzo

    2016-05-01

    A strong correlation exists between the total mass of a globular cluster (GC) system and the virial halo mass of the host galaxy. However, the total halo mass in this correlation is a statistical measure conducted on spatial scales that are some 10 times that of a typical GC system. Here we investigate the connection between GC systems and galaxy's dark matter on comparable spatial scales, using dynamical masses measured on a galaxy-by-galaxy basis. Our sample consists of 17 well-studied massive (˜1011 M⊙) early-type galaxies from the SLUGGS survey. We find the strongest correlation to be that of the blue (metal-poor) GC subpopulation and the dark matter content. This correlation implies that the dark matter mass of a galaxy can be estimated to within a factor of 2 from careful imaging of its GC system. The ratio of the GC system mass to that of the enclosed dark matter is nearly constant. We also find a strong correlation between the fraction of blue GCs and the fraction of enclosed dark matter, so that a typical galaxy with a blue GC fraction of 60 per cent has a dark matter fraction of 86 per cent over similar spatial scales. Both halo growth and removal (via tidal stripping) may play some role in shaping this trend. In the context of the two-phase model for galaxy formation, we find galaxies with the highest fractions of accreted stars to have higher dark matter fractions for a given fraction of blue GCs.

  16. Star formation associated with neutral hydrogen in the outskirts of early-type galaxies

    Science.gov (United States)

    Yldz, Mustafa K.; Serra, Paolo; Peletier, Reynier F.; Oosterloo, Tom A.; Duc, Pierre-Alain

    2016-09-01

    About 20 percent of all nearby early-type galaxies (M⋆ ≳ ~6~ × 109~M⊙) outside the Virgo cluster are surrounded by a disc or ring of low-column-density neutral hydrogen (H I) gas with typical radii of tens of kpc, much larger than the stellar body. In order to understand the impact of these gas reservoirs on the host galaxies, we analyse the distribution of star formation out to large radii as a function of H I properties using GALEX UV and SDSS optical images. Our sample consists of 18 H I-rich galaxies as well as 55 control galaxies where no H I has been detected. In half of the H I-rich galaxies the radial UV profile changes slope at the position of the H I radial profile peak. To study the stellar populations, we calculate the FUV-NUV and UV-optical colours in two apertures, 1-3 and 3-10 Reff. We find that H I-rich galaxies are on average 0.5 and 0.8 mag bluer than the H I-poor ones, respectively. This indicates that a significant fraction of the UV emission traces recent star formation and is associated with the H I gas. Using FUV emission as a proxy for star formation, we estimate the integrated star formation rate in the outer regions (R > 1Reff) to be on average ˜ 6× 10-3 M⊙~yr-1 for the H I-rich galaxies. This rate is too low to build a substantial stellar disc and, therefore, change the morphology of the host. We find that the star formation efficiency and the gas depletion time are similar to those at the outskirts of spirals.

  17. AN INVENTORY OF THE STELLAR INITIAL MASS FUNCTION IN EARLY-TYPE GALAXIES

    Energy Technology Data Exchange (ETDEWEB)

    Tortora, C. [Institut fuer Theoretische Physik, Universitaet Zuerich, Winterthurerstrasse 190, CH-8057 Zuerich (Switzerland); Romanowsky, A. J. [University of California Observatories, 1156 High Street, Santa Cruz, CA 95064 (United States); Napolitano, N. R., E-mail: ctortora@physik.uzh.ch [INAF-Osservatorio Astronomico di Capodimonte, Salita Moiariello 16, I-80131 Napoli (Italy)

    2013-03-01

    Given a flurry of recent claims for systematic variations in the stellar initial mass function (IMF), we carry out the first inventory of the observational evidence using different approaches. This includes literature results, as well as our own new findings from combined stellar population synthesis (SPS) and Jeans dynamical analyses of data on {approx}4500 early-type galaxies (ETGs) from the SPIDER project. We focus on the mass-to-light ratio mismatch relative to the Milky Way IMF, {delta}{sub IMF}, correlated against the central stellar velocity dispersion, {sigma}{sub *}. We find a strong correlation between {delta}{sub IMF} and {sigma}{sub *}, for a wide set of dark matter (DM) model profiles. These results are robust if a uniform halo response to baryons is adopted across the sample. The overall normalization of {delta}{sub IMF} and the detailed DM profile are less certain, but the data are consistent with standard cold DM halos and a central DM fraction that is roughly constant with {sigma}{sub *}. For a variety of related studies in the literature, using SPS, dynamics, and gravitational lensing, similar results are found. Studies based solely on spectroscopic line diagnostics agree on a Salpeter-like IMF at high {sigma}{sub *} but differ at low {sigma}{sub *}. Overall, we find that multiple independent lines of evidence appear to be converging on a systematic variation in the IMF, such that high-{sigma}{sub *} ETGs have an excess of low-mass stars relative to spirals and low-{sigma}{sub *} ETGs. Robust verification of super-Salpeter IMFs in the highest-{sigma}{sub *} galaxies will require additional scrutiny of scatter and systematic uncertainties. The implications for the distribution of DM are still inconclusive.

  18. Star formation and nuclear activity in the blue early-type galaxy NGC 5373

    Science.gov (United States)

    Zaidi, Tayeb; Miller, Brendan P.; Gallo, Elena; Alfvin, Erik; Martinkus, Charlotte; Molter, Edward

    2015-01-01

    We present new optical and X-ray observations of NGC 5373, an isolated star-forming elliptical that has a stellar mass of 7e10 solar and lies at a distance of 175 Mpc. Our B and R band Magellan IMACS imaging substantially improves on SDSS resolution and sensitivity, enabling accurate modeling of the galaxy surface brightness profile. As expected from its mass, NGC 5373 is a core galaxy with a best-fit Sersic profile of n~3.8; no prominent tidal tails or shells are found, although there are slight residual asymmetries. The H-alpha emission in the SDSS spectrum is narrow, and the line ratios confirm a star-forming classification in the BPT diagram, near the transition/composite line. The star formation rate is about 6 solar masses per year, making NGC 5373 an extreme outlier relative to typical local early-type galaxies of similar mass. Our 50 ks Chandra ACIS-S exposure provides a clear detection of a central X-ray source, with a hardness ratio consistent with a power-law photon index of 2.0+/-0.5. The unabsorbed luminosity is Lx = 2e40 erg/s over 0.3-8 keV. Comparison with a MARX simulated point spread function suggests the central source may be extended, for example due to contributions from one or more unresolved high-mass X-ray binaries, as might be present given the high star formation rate. For a black hole of 1.6e8 solar masses as predicted from scaling relations, Lx/Ledd is then around 1e-6 (or potentially lower).

  19. The early gaseous and stellar mass assembly of Milky Way-type galaxy haloes

    Science.gov (United States)

    Hensler, Gerhard

    2015-08-01

    In cosmological simulations of Cold Dark Matter (CDM) structure formation a vast number of subhalos is expected around massive galaxies like the Milky Way (MW). These DM subhalos are filled with baryons, gas that forms stars very early as observed from the stellar populations in the MW satellite galaxies. Satellite galaxies evolve in the tidal field of their mature galaxy and suffer accretion to the major galaxy and their partly disruption. By this, their mass loss is expected to feed the galaxy halo with stars and gas.From the Via Lactea II simulations we select a massive DM halo with its satellite system which evolves in the simulations to a present-day MW-type galaxy. We follow its evolution from redshift 4.5 to 2.5, i.e. over almost 2 billion years of the most interesting epoch of mass assembly. A high mass resolution allows for even low-mass satellites down to 10^5 Msun, but limits their distance range to the innermost 240 satellites of the system only. The applied chemo-dynamical method includes star formation, stellar energetic and chemical feedback, and gas physical processes.After the onset of the simulation our models demonstrate the action of tidal effects and satellite merging on the star-formation rate of the satellites, their gas loss by means of hot-gas expansion, of ram-pressure and tidal stripping, and the tidal extraction of stars, leading to the formation of the stellar and gaseous galactic halo. We also analyze the evolution of the satellites’ mass function, their baryonic and DM mass distributions, chemical abundances, their compactness, their present-day appearance, etc. with respect to observations and present-day correlations.

  20. Systematic trends in total-mass profiles from dynamical models of early-type galaxies

    Science.gov (United States)

    Poci, Adriano; Cappellari, Michele; McDermid, Richard M.

    2017-01-01

    We study trends in the slope of the total mass profiles and dark matter fractions within the central half-light radius of 258 early-type galaxies, using data from the volume-limited ATLAS3D survey. We use three distinct sets of dynamical models, which vary in their assumptions and also allow for spatial variations in the stellar mass-to-light ratio, to test the robustness of our results. We confirm that the slopes of the total mass profiles are approximately isothermal, and investigate how the total-mass slope depends on various galactic properties. The most statistically-significant correlations we find are a function of either surface density, Σe, or velocity dispersion, σe. However there is evidence for a break in the latter relation, with a nearly universal logarithmic slope above log10[σe/(km s-1)] ˜ 2.1 and a steeper trend below this value. For the 142 galaxies above that critical σe value, the total mass-density logarithmic slopes have a mean value = -2.193 ± 0.016 (1σ error) with an observed rms scatter of only σ _{γ ^' }= 0.168 ± 0.015. Considering the observational errors, we estimate an intrinsic scatter of σ _{γ ^' }^intr ≈ 0.15. These values are broadly consistent with those found by strong lensing studies at similar radii and agree, within the tight errors, with values recently found at much larger radii via stellar dynamics or HI rotation curves (using significantly smaller samples than this work).

  1. Well-Being and Diabetes Management in Early Pregnant Women with Type 1 Diabetes Mellitus

    Directory of Open Access Journals (Sweden)

    Karolina Linden

    2016-08-01

    Full Text Available This paper explores well-being and diabetes management in women with type 1 diabetes mellitus (DM in early pregnancy and investigates associations among perceived well-being, diabetes management, and maternal characteristics. Questionnaires were answered by 168 Swedish women. Correlation analyses were conducted with Spearman’s correlation coefficient (rs. The women reported relatively high scores of self-efficacy in diabetes management (SWE-DES-10: 3.91 (0.51 and self-perceived health (excellent (6.5%, very good (42.3%, good (38.7%, fair (11.3% and poor (1.2%. Moderate scores were reported for general well-being (WBQ-12: 22.6 (5.7 and sense of coherence (SOC-13: 68.9 (9.7, moderate/low scores for hypoglycemia fear (SWE-HFS 26.6 (11.8 and low scores of diabetes-distress (SWE-PAID-20 27.1 (15.9. A higher capability of self-efficacy in diabetes management showed positive correlations with self-perceived health (rs = −0.41, p < 0.0001 and well-being (rs = 0.34, p < 0.0001 as well as negative correlations with diabetes distress (rs = −0.51, p < 0.0001 and hypoglycemia worries (rs = −0.27, p = 0.0009. Women with HbA1c levels of ≤48 mmL/mol scored higher in the subscales “goal achievement” in SWE-DES (p = 0.0028 and “comprehensibility” in SOC (p = 0.016. Well-being and diabetes management could be supported by strengthening the women’s capability to achieve glycemic goals and their comprehensibility in relation to the treatment. Further studies are needed to test this.

  2. Crustal types, distribution of salt and the early evolution of the Gulf of Mexico basin

    Energy Technology Data Exchange (ETDEWEB)

    Buffler, R.T. (Univ. of Texas, Austin (USA))

    1990-05-01

    A new contour map on the top of basement shows the overall configuration of the entire Gulf of Mexico basin. Basement, as used here, is all rocks lying below (older than) the extensive Middle Jurassic (Callovian ) premarine evaporites (Louann Salt, etc.) plus the Late Jurassic oceanic crust in the deep part of the basin. The contour map combined with all other available geophysical data has been used to subdivide the gulf basin into four crustal types: continental, thick transitional, thin transitional, and oceanic crust. The broad region of transitional crust and the basic architecture of the basin shown by the map is believed to have formed mainly during a separate Middle Jurassic period of widespread attenuation of the entire gulf region. The area of thick transitional crust around the periphery of the northern gulf is characterized by broad basement highs and lows with wave lengths of 200-300 km. These features controlled the general distribution and thickness of salt and the overlying Jurassic through Lower Cretaceous rocks. In the area of thin transitional crust Mesozoic basins tend to be assymetrical and generally trend more parallel to the overall basin. The boundary between thin transitional crust and oceanic crust is characterized by various salt-related features. For example, the northwest and north-central boundaries are defined by two northeast trending salt-cored foldbelts, the Perdido and Mississippi fan foldbelts, respectively. The offset between the two foldbelts may represent a major transform boundary related to the northwest opening of the gulf basin. All these data put important constraints on models for early gulf evolution.

  3. Organ specific autoantibodies in preclinical and early clinical type 1 diabetes in Turkey.

    Science.gov (United States)

    Erten, G; Gurol, A O; Deniz, G; Satman, I; Yilmaz, M T

    2007-01-01

    Type 1 diabetes mellitus (T1D) patients (G1; n=73) and first degree relatives with islet cell antibody (ICA) values of >or=10 JDF u twice or >or=20 JDF u one and loss of FPIR (G2; n=18) were screened for two other autoantibodies, anti-glutamic acid decarboxylase (GADA) and insulin autoantibodies (IAA), and for other organ-specific autoantibodies, anti-gastric parietal cell (anti-PCA) and anti-thyroid peroxidase (anti-TPO) as well. The two control groups consisted of healthy subjects (G3; n:55 and G4; n:13). In G1, positivity of ICA, GADA, IAA, anti-TPO and anti-PCA were 63%, 75.1%, 27.4%, 17.8% and 8.2%, respectively. In G2, positivity for GADA, IAA, anti-TPO and anti-PCA were 55.6%, 11.1%, 16.7% and 11.1%, respectively. None of the anti-TPO or anti-PCA positive cases had clinical or laboratory thyroid disease or pernicious anemia. Other organ specific antibodies, in case they accompany GADAand/or IAA in high risk individuals, result in higher risk for T1D. Moreover, this condition may indicate future potential for developing thyrogastric autoimmune diseases. In conclusion; autoantibodies are markers for autoimmune destruction in T1D, and for identification of subjects at risk for disease. Even at the time of diagnosis of T1D, screening for thyrogastric autoimmunity might be recommended for early detection of the relevant diseases.

  4. Low cardiorespiratory fitness in people at risk for type 2 diabetes: early marker for insulin resistance

    Directory of Open Access Journals (Sweden)

    Leite Silmara AO

    2009-09-01

    Full Text Available Abstract Purpose There is a significant association between insulin resistance and low cardiorespiratory fitness in nondiabetic subjects. In a population with risk factors for type 2 diabetes (T2DM, before they are insulin resistant, we investigated low exercise capacity (VO2max as an early marker of impaired insulin sensitivity in order to determine earlier interventions to prevent development of insulin resistance syndrome (IRS and T2DM. Methods Cross-sectional analyses of data on 369 (78 men and 291 women people at risk for IRS and T2DM, aged 45.6 +/- 10 years (20-65 years old from the Community Diabetes Prevention Project in Minnesota were carried out. The cardiorespiratory fitness (VO2max by respiratory gas exchange and bicycle ergometer were measured in our at risk non insulin resistant population and compared with a control group living in the same geographic area. Both groups were equally sedentary, matched for age, gender and BMI. Results The most prevalent abnormality in the study population was markedly low VO2max when compared with general work site screening control group, (n = 177; 137F; 40 M, mean age 40 ± 11 years; BMI = 27.8 ± 6.1 kg/m2. Individuals at risk for IRS and T2DM had a VO2max (22 ± 6 ml/kg/min 15% lower than the control group VO2max (26 ± 9 ml/kg/min (p 2max was inversely correlated with HOMA-IR (r = -0.30, p Conclusions Decreased VO2max is correlated with impaired insulin sensitivity and was the most prevalent abnormality in a population at risk for IRS and T2DM but without overt disease. This raises the possibility that decreased VO2 max is among the earliest indicators of IRS and T2DM therefore, an important risk factor for disease progression.

  5. Star formation associated with neutral hydrogen in the outskirts of early-type galaxies

    Science.gov (United States)

    Yıldız, Mustafa K.; Serra, Paolo; Peletier, Reynier F.; Oosterloo, Tom A.; Duc, Pierre-Alain

    2017-01-01

    About 20 per cent of all nearby early-type galaxies (M⋆ ≳ 6 × 109 M⊙) outside the Virgo cluster are surrounded by a disc or ring of low-column-density neutral hydrogen (H I) gas with typical radii of tens of kpc, much larger than the stellar body. In order to understand the impact of these gas reservoirs on the host galaxies, we analyse the distribution of star formation out to large radii as a function of H I properties using GALEX UV and SDSS optical images. Our sample consists of 18 H I-rich galaxies as well as 55 control galaxies where no H I has been detected. In half of the H I-rich galaxies, the radial UV profile changes slope at the position of the H I radial profile peak. To study the stellar populations, we calculate the FUV-NUV and UV-optical colours in two apertures, 1-3 and 3-10 Reff. We find that H I-rich galaxies are on average 0.5 and 0.8 mag bluer than the H I-poor ones, respectively. This indicates that a significant fraction of the UV emission traces recent star formation and is associated with the H I gas. Using FUV emission as a proxy for star formation, we estimate the integrated star formation rate in the outer regions (R > 1Reff) to be on average ˜6 × 10-3 M⊙ yr-1 for the H I-rich galaxies. This rate is too low to build a substantial stellar disc and, therefore, change the morphology of the host. We find that the star formation efficiency and the gas depletion time are similar to those at the outskirts of spirals.

  6. An Inventory of the Stellar Initial Mass Function in Early-type Galaxies

    Science.gov (United States)

    Tortora, C.; Romanowsky, A. J.; Napolitano, N. R.

    2013-03-01

    Given a flurry of recent claims for systematic variations in the stellar initial mass function (IMF), we carry out the first inventory of the observational evidence using different approaches. This includes literature results, as well as our own new findings from combined stellar population synthesis (SPS) and Jeans dynamical analyses of data on ~4500 early-type galaxies (ETGs) from the SPIDER project. We focus on the mass-to-light ratio mismatch relative to the Milky Way IMF, δIMF, correlated against the central stellar velocity dispersion, σsstarf. We find a strong correlation between δIMF and σsstarf, for a wide set of dark matter (DM) model profiles. These results are robust if a uniform halo response to baryons is adopted across the sample. The overall normalization of δIMF and the detailed DM profile are less certain, but the data are consistent with standard cold DM halos and a central DM fraction that is roughly constant with σsstarf. For a variety of related studies in the literature, using SPS, dynamics, and gravitational lensing, similar results are found. Studies based solely on spectroscopic line diagnostics agree on a Salpeter-like IMF at high σsstarf but differ at low σsstarf. Overall, we find that multiple independent lines of evidence appear to be converging on a systematic variation in the IMF, such that high-σsstarf ETGs have an excess of low-mass stars relative to spirals and low-σsstarf ETGs. Robust verification of super-Salpeter IMFs in the highest-σsstarf galaxies will require additional scrutiny of scatter and systematic uncertainties. The implications for the distribution of DM are still inconclusive.

  7. Systematic variations of central mass density slopes in early-type galaxies

    Science.gov (United States)

    Tortora, C.; La Barbera, F.; Napolitano, N. R.; Romanowsky, A. J.; Ferreras, I.; de Carvalho, R. R.

    2014-11-01

    We study the total density distribution in the central regions (≲1 effective radius, Re) of early-type galaxies (ETGs), using data from SPIDER and ATLAS3D. Our analysis extends the range of galaxy stellar mass (M⋆) probed by gravitational lensing, down to ˜ 1010 M⊙. We model each galaxy with two components (dark matter halo + stars), exploring different assumptions for the dark matter halo profile (i.e. NFW, NFW-contracted, and Burkert profiles), and leaving stellar mass-to-light (M⋆/L) ratios as free fitting parameters to the data. For all plausible halo models, the best-fitting M⋆/L, normalized to that for a Chabrier initial mass function, increases systematically with galaxy size and mass. For an NFW profile, the slope of the total mass profile is non-universal, independently of several ingredients in the modelling (e.g. halo contraction, anisotropy, and rotation velocity in ETGs). For the most massive (M⋆ ˜ 1011.5 M⊙) or largest (Re˜ 15 kpc) ETGs, the profile is isothermal in the central regions (˜ Re/2), while for the low-mass (M⋆ ˜ 1010.2 M⊙) or smallest (Re˜ 0.5 kpc) systems, the profile is steeper than isothermal, with slopes similar to those for a constant-M/L profile. For a steeper concentration-mass relation than that expected from simulations, the correlation of density slope with galaxy mass tends to flatten, while correlations with Re and velocity dispersions are more robust. Our results clearly point to a `non-homology' in the total mass distribution of ETGs, which simulations of galaxy formation suggest may be related to a varying role of dissipation with galaxy mass.

  8. Early observations of the nearby Type Ia supernova SN 2015F

    Science.gov (United States)

    Cartier, R.; Sullivan, M.; Firth, R. E.; Pignata, G.; Mazzali, P.; Maguire, K.; Childress, M. J.; Arcavi, I.; Ashall, C.; Bassett, B.; Crawford, S. M.; Frohmaier, C.; Galbany, L.; Gal-Yam, A.; Hosseinzadeh, G.; Howell, D. A.; Inserra, C.; Johansson, J.; Kasai, E. K.; McCully, C.; Prajs, S.; Prentice, S.; Schulze, S.; Smartt, S. J.; Smith, K. W.; Smith, M.; Valenti, S.; Young, D. R.

    2017-02-01

    We present photometry and time series spectroscopy of the nearby Type Ia supernova (SN Ia) SN 2015F over -16 d to +80 d relative to maximum light, obtained as part of the Public ESO Spectroscopic Survey of Transient Objects. SN 2015F is a slightly sub-luminous SN Ia with a decline rate of Δm15(B) = 1.35 ± 0.03 mag, placing it in the region between normal and SN 1991bg-like events. Our densely sampled photometric data place tight constraints on the epoch of first light and form of the early-time light curve. The spectra exhibit photospheric C II λ6580 absorption until -4 days, and high-velocity Ca II is particularly strong at 14 000 km s-1, suggesting mixing in the outermost layers of the SN ejecta. Although unusual in SN Ia spectra, including V II in the modelling significantly improves the spectral fits. Intriguingly, we detect an absorption feature at ˜6800 Å that persists until maximum light. Our favoured explanation for this line is photospheric Al II, which has never been claimed before in SNe Ia, although detached high-velocity C II material could also be responsible. In both cases, the absorbing material seems to be confined to a relatively narrow region in velocity space. The nucleosynthesis of detectable amounts of Al II would argue against a low-metallicity white dwarf progenitor. We also show that this 6800 Å feature is weakly present in other normal SN Ia events and common in the SN 1991bg-like sub-class.

  9. Multiwavelength Study of Radio Loud Early-Type Galaxies from the B2 Sample

    Science.gov (United States)

    Sahu, Sheetal Kumar; Chaware, Laxmikant; Pandey, S. K.; Kulkarni, Samridhi; Pandge, M. B.; Chakradhari, N. K.

    2014-07-01

    We present multiwavelength study of a sample of radio loud early-type galaxies chosen from the B2 sample. We performed surface photometry in BVR broad band filters and Hα narrow band filter on CCD images of sample galaxies using IGO 2m telescope, Pune (INDIA), to get radial profiles of various photometric and geometrical parameters that describe elliptical isophotes fitted to the 2D light distribution of the galaxies. The analysis of radial profiles of quantities such as the (local) surface brightness, the ellipticity, and the deviations from elliptical isophotes parametrized by the Fourier coefficients are main focus of our study. We generated color maps, residual maps, and dust extinction maps, Hα emission maps of the galaxies to study the morphology of the dust and ionized gas content present in the galaxies. We carried out detailed analysis of the properties of the dust present in our sample galaxies. Additionaly, we investigated properties of the dust in the central ~10 arcsec region of our sample galaxies using optical images available from the HST (WFPC2) data archive. We estimated mass and temperature of the dust, molecular gas mass, in the sample galaxies using FIR fluxes of the galaxies obtained from IRAS. We used spectroscopic data available from the SDSS (DR7) to get an estimate of the mass of the central super massive black-hole for B2 1257+28 (NGC 4874). We plotted rotation curve for coma cluster (Abell 1656), which indicates the presence of dark matter halo around the galaxy B2 1257+28.

  10. EARLY-TYPE GALAXIES AT z {approx} 1.3. IV. SCALING RELATIONS IN DIFFERENT ENVIRONMENTS

    Energy Technology Data Exchange (ETDEWEB)

    Raichoor, A.; Mei, S.; Huertas-Company, M. [GEPI, Observatoire de Paris, Section de Meudon, 92190 Meudon Cedex (France); Stanford, S. A.; Rettura, A.; Jee, M. J. [Department of Physics, University of California, Davis, CA 95616 (United States); Holden, B. P.; Illingworth, G. [UCO/Lick Observatories, University of California, Santa Cruz, CA 95065 (United States); Nakata, F.; Kodama, T. [Subaru Telescope, National Astronomical Observatory of Japan, Hilo, HI 96720 (United States); Rosati, P. [European South Observatory, D-85748 Garching (Germany); Shankar, F. [Max-Planck-Instituet fuer Astrophysik, D-85748 Garching (Germany); Tanaka, M. [Institute for the Physics and Mathematics of the Universe, The University of Tokyo, Chiba 277-8583 (Japan); Ford, H. [Department of Physics and Astronomy, Johns Hopkins University, Baltimore, MD 21218 (United States); Postman, M.; White, R. L. [Space Telescope Science Institute, Baltimore, MD 21218 (United States); Blakeslee, J. P. [Herzberg Institute of Astrophysics, National Research Council of Canada, Victoria, BC V9E 2E7 (Canada); Demarco, R., E-mail: anand.raichoor@brera.inaf.it [Department of Astronomy, Universidad de Concepcion, Casilla 160-C, Concepcion (Chile)

    2012-02-01

    We present the Kormendy and mass-size relations (MSR) for early-type galaxies (ETGs) as a function of environment at z {approx} 1.3. Our sample includes 76 visually classified ETGs with masses 10{sup 10} < M/M{sub Sun} < 10{sup 11.5}, selected in the Lynx supercluster and in the Great Observatories Origins Deep Survey/Chandra Deep Field South field; 31 ETGs in clusters, 18 in groups, and 27 in the field, all with multi-wavelength photometry and Hubble Space Telescope/Advanced Camera for Surveys observations. The Kormendy relation, in place at z {approx} 1.3, does not depend on the environment. The MSR reveals that ETGs overall appear to be more compact in denser environments: cluster ETGs have sizes on average around 30%-50% smaller than those of the local universe and a distribution with a smaller scatter, whereas field ETGs show an MSR with a similar distribution to the local one. Our results imply that (1) the MSR in the field did not evolve overall from z {approx} 1.3 to present; this is interesting and in contrast to the trend found at higher masses from previous works; (2) in denser environments, either ETGs have increased in size by 30%-50% on average and spread their distributions, or more ETGs have been formed within the dense environment from non-ETG progenitors, or larger galaxies have been accreted to a pristine compact population to reproduce the MSR observed in the local universe. Our results are driven by galaxies with masses M {approx}< 2 Multiplication-Sign 10{sup 11} M{sub Sun} and those with masses M {approx} 10{sup 11} M{sub Sun} follow the same trends as that of the entire sample. Following the Valentinuzzi et al. definition of superdense ETGs, {approx}35%-45% of our cluster sample is made up of superdense ETGs.

  11. Pentacyclic triterpenes in birch bark extract inhibit early step of herpes simplex virus type 1 replication.

    Science.gov (United States)

    Heidary Navid, M; Laszczyk-Lauer, M N; Reichling, J; Schnitzler, P

    2014-09-25

    Antiviral agents frequently applied for treatment of herpesvirus infections include acyclovir and its derivatives. The antiviral effect of a triterpene extract of birch bark and its major pentacyclic triterpenes, i.e. betulin, lupeol and betulinic acid against acyclovir-sensitive and acyclovir-resistant HSV type 1 strains was examined. The cytotoxic effect of a phytochemically defined birch bark triterpene extract (TE) as well as different pentacyclic triterpenes was analyzed in cell culture, and revealed a moderate cytotoxicity on RC-37 cells. TE, betulin, lupeol and betulinic acid exhibited high levels of antiviral activity against HSV-1 in viral suspension tests with IC50 values ranging between 0.2 and 0.5 μg/ml. Infectivity of acyclovir-sensitive and clinical isolates of acyclovir-resistant HSV-1 strains was significantly reduced by all tested compounds and a direct concentration- and time-dependent antiherpetic activity could be demonstrated. In order to determine the mode of antiviral action, TE and the compounds were added at different times during the viral infection cycle. Addition of these drugs to uninfected cells prior to infection or to herpesvirus-infected cells during intracellular replication had low effect on virus multiplication. Minor virucidal activity of triterpenes was observed, however both TE and tested compounds exhibited high anti-herpetic activity when viruses were pretreated with these drugs prior to infection. Pentacyclic triterpenes inhibit acyclovir-sensitive and acyclovir-resistant clinical isolates of HSV-1 in the early phase of infection. Copyright © 2014 Elsevier GmbH. All rights reserved.

  12. The Herschel Virgo Cluster Survey. XIII. Dust in early-type galaxies

    Science.gov (United States)

    di Serego Alighieri, S.; Bianchi, S.; Pappalardo, C.; Zibetti, S.; Auld, R.; Baes, M.; Bendo, G.; Corbelli, E.; Davies, J. I.; Davis, T.; De Looze, I.; Fritz, J.; Gavazzi, G.; Giovanardi, C.; Grossi, M.; Hunt, L. K.; Magrini, L.; Pierini, D.; Xilouris, E. M.

    2013-04-01

    Aims: We study the dust content of a large optical input sample of 910 early-type galaxies (ETG) in the Virgo cluster, also extending to the dwarf ETG, and examine the results in relation to those on the other cold ISM components. Methods: We have searched for far-infrared emission in all galaxies in the input sample using the 250 μm image of the Herschel Virgo Cluster Survey (HeViCS). This image covers a large fraction of the cluster with an area of ~55 square degrees. For the detected ETG we measured fluxes in five bands from 100 to 500 μm, and estimated the dust mass and temperature with modified black-body fits. Results: Dust is detected above the completeness limit of 25.4 mJy at 250 μm in 46 ETG, 43 of which are in the optically complete part of the input sample. In addition, dust is present at fainter levels in another six ETG. We detect dust in the four ETG with synchrotron emission, including M 87. Dust appears to be much more concentrated than stars and more luminous ETG have higher dust temperatures. Considering only the optically complete input sample and correcting for the contamination by background galaxies, dust detection rates down to the 25.4 mJy limit are 17% for ellipticals, about 40% for lenticulars (S0 + S0a), and around 3% for dwarf ETG. Dust mass does not correlate clearly with stellar mass and is often much greater than expected for a passive galaxy in a closed-box model. The dust-to-stars mass ratio anticorrelates with galaxy luminosity, and for some dwarf ETG reaches values as high as for dusty late-type galaxies. In the Virgo cluster slow rotators appear more likely to contain dust than fast ones. Comparing the dust results with those on Hi there are only eight ETG detected both in dust and in Hi in the HeViCS area; 39 have dust but only an upper limit on Hi, and eight have Hi but only an upper limit on dust. The locations of these galaxies in the cluster are different, with the dusty ETG concentrated in the densest regions, while the

  13. Verbal and Academic Skills in Children with Early-Onset Type 1 Diabetes

    Science.gov (United States)

    Hannonen, Riitta; Komulainen, Jorma; Eklund, Kenneth; Tolvanen, Asko; Riikonen, Raili; Ahonen, Timo

    2010-01-01

    Aim: Basic verbal and academic skills can be adversely affected by early-onset diabetes, although these skills have been studied less than other cognitive functions. This study aimed to explore the mechanism of learning deficits in children with diabetes by assessing basic verbal and academic skills in children with early-onset diabetes and in…

  14. Verbal and Academic Skills in Children with Early-Onset Type 1 Diabetes

    Science.gov (United States)

    Hannonen, Riitta; Komulainen, Jorma; Eklund, Kenneth; Tolvanen, Asko; Riikonen, Raili; Ahonen, Timo

    2010-01-01

    Aim: Basic verbal and academic skills can be adversely affected by early-onset diabetes, although these skills have been studied less than other cognitive functions. This study aimed to explore the mechanism of learning deficits in children with diabetes by assessing basic verbal and academic skills in children with early-onset diabetes and in…

  15. Visual association test to detect early dementia of the Alzheimer type

    Science.gov (United States)

    Lindeboom, J; Schmand, B; Tulner, L; Walstra, G; Jonker, C

    2002-01-01

    Background: The visual association test (VAT) is a brief learning task based on imagery mnemonics. The test materials consist of six line drawings of pairs of interacting objects or animals—for example, an ape holding an umbrella. The person is asked to name each object and, later, is presented with one object from the pair and asked to name the other. Objective: To verify that the task induces robust incidental or effortless learning (study 1), and to study the efficiency of the test as a discriminator between early dementia of the Alzheimer type (DAT) and non-demented people (study 2) and non-DAT types of dementia (study 3). Methods: Study 1: two groups of elderly volunteers were administered the VAT. The stimuli were presented in the interactive fashion to group A—for example, a monkey carrying an umbrella (n=83)—and side by side to group B—for example, separate pictures of a monkey alone and an umbrella alone (n=79). Group B received learning instructions, but group A did not. Study 2: three groups of subjects were selected from a population based follow up study: incident DAT cases (n=24), cognitively declining subjects not diagnosed with dementia (n=21), and stable non-demented subjects (n=204). Test performance of the non-demented group at baseline was compared with that of patients with DAT at the time of their diagnosis, of patients with DAT a year before their diagnosis, and of non-demented declining subjects at baseline. Study 3: subjects were patients referred for neuropsychological assessment because of suspected dementia. They were diagnosed by consensus criteria of various dementia syndromes. Results: Study 1: recall was more than twice as high in group A as in group B. Thus interactive presentation, even in the absence of learning instructions, enhances learning. Study 2: at a level of 97.5% specificity, the VAT had a sensitivity of 87.5% for DAT cases at the time of diagnosis and 66.7% one year before diagnosis. The cognitively declining

  16. Functional limitations of plasmacytoid dendritic cells limit type I interferon, T cell responses and virus control in early life.

    Directory of Open Access Journals (Sweden)

    Elodie Belnoue

    Full Text Available Infant mortality from viral infection remains a major global health concern: viruses causing acute infections in immunologically mature hosts often follow a more severe course in early life, with prolonged or persistent viral replication. Similarly, the WE strain of lymphocytic choriomeningitis virus (LCMV-WE causes acute self-limiting infection in adult mice but follows a protracted course in infant animals, in which LCMV-specific CD8⁺ T cells fail to expand and control infection. By disrupting type I IFNs signaling in adult mice or providing IFN-α supplementation to infant mice, we show here that the impaired early life T cell responses and viral control result from limited early type I IFN responses. We postulated that plasmacytoid dendritic cells (pDC, which have been identified as one major source of immediate-early IFN-I, may not exert adult-like function in vivo in the early life microenvironment. We tested this hypothesis by studying pDC functions in vivo during LCMV infection and identified a coordinated downregulation of infant pDC maturation, activation and function: despite an adult-like in vitro activation capacity of infant pDCs, the expression of the E2-2 pDC master regulator (and of critical downstream antiviral genes such as MyD88, TLR7/TLR9, NF-κB, IRF7 and IRF8 is downregulated in vivo at baseline and during LCMV infection. A similar pattern was observed in response to ssRNA polyU, a model ligand of the TLR7 viral sensor. This suggests that the limited T cell-mediated defense against early life viral infections is largely attributable to / regulated by infant pDC responses and provides incentives for novel strategies to supplement or stimulate immediate-early IFN-α responses.

  17. Neddylation is required for herpes simplex virus type I (HSV-1)-induced early phase interferon-beta production.

    Science.gov (United States)

    Zhang, Xueying; Ye, Zhenjie; Pei, Yujun; Qiu, Guihua; Wang, Qingyang; Xu, Yunlu; Shen, Beifen; Zhang, Jiyan

    2016-09-01

    Type I interferons such as interferon-beta (IFN-β) play essential roles in the host innate immune response to herpes simplex virus type I (HSV-1) infection. The transcription of type I interferon genes is controlled by nuclear factor-κB (NF-κB) and interferon regulatory factor (IRF) family members including IRF3. NF-κB activation depends on the phosphorylation of inhibitor of κB (IκB), which triggers its ubiqitination and degradation. It has been reported that neddylation inhibition by a pharmacological agent MLN4924 potently suppresses lipopolysaccharide (LPS)-induced proinflammatory cytokine production with the accumulation of phosphorylated IκBα. However, the role of neddylation in type I interferon expression remains unknown. Here, we report that neddylation inhibition with MLN4924 or upon UBA3 deficiency led to accumulation of phosphorylated IκBα, impaired IκBα degradation, and impaired NF-κB nuclear translocation in the early phase of HSV-1 infection even though phosphorylation and nuclear translocation of IRF3 were not affected. The blockade of NF-κB nuclear translocation by neddylation inhibition becomes less efficient at the later time points of HSV-1 infection. Consequently, HSV-1-induced early phase IFN-β production significantly decreased upon MLN4924 treatment and UBA3 deficiency. NF-κB inhibitor JSH-23 mimicked the effects of neddylation inhibition in the early phase of HSV-1 infection. Moreover, the effects of neddylation inhibition on HSV-1-induced early phase IFN-β production diminished in the presence of NF-κB inhibitor JSH-23. Thus, neddylation contributes to HSV-1-induced early phase IFN-β production through, at least partially, promoting NF-κB activation.

  18. Formaldehyde in Absorption: Tracing Molecular Gas in Early-Type Galaxies

    Science.gov (United States)

    Dollhopf, Niklaus M.; Donovan Meyer, Jennifer

    2016-01-01

    Early-Type Galaxies (ETGs) have been long-classified as the red, ellipsoidal branch of the classic Hubble tuning fork diagram of galactic structure. In part with this classification, ETGs are thought to be molecular and atomic gas-poor with little to no recent star formation. However, recent efforts have questioned this ingrained classification. Most notably, the ATLAS3D survey of 260 ETGs within ~40 Mpc found 22% contain CO, a common tracer for molecular gas. The presence of cold molecular gas also implies the possibility for current star formation within these galaxies. Simulations do not accurately predict the recent observations and further studies are necessary to understand the mechanisms of ETGs.CO traces molecular gas starting at densities of ~102 cm-3, which makes it a good tracer of bulk molecular gas, but does little to constrain the possible locations of star formation within the cores of dense molecular gas clouds. Formaldehyde (H2CO) traces molecular gas on the order of ~104 cm-3, providing a further constraint on the location of star-forming gas, while being simple enough to possibly be abundant in gas-poor ETGs. In cold molecular clouds at or above ~104 cm-3 densities, the structure of formaldehyde enables a phenomenon in which rotational transitions have excitation temperatures driven below the temperature of the cosmic microwave background (CMB), ~2.7 K. Because the CMB radiates isotropically, formaldehyde can be observed in absorption, independent of distance, as a tracer of moderately-dense molecular clouds and star formation.This novel observation technique of formaldehyde was incorporated for observations of twelve CO-detected ETGs from the ATLAS3D sample, including NGC 4710 and PGC 8815, to investigate the presence of cold molecular gas, and possible star formation, in ETGs. We present images from the Very Large Array, used in its C-array configuration, of the J = 11,0 - 11,1 transition of formaldehyde towards these sources. We report our

  19. Identifying Niemann-Pick type C in early-onset ataxia: two quick clinical screening tools.

    Science.gov (United States)

    Synofzik, Matthis; Fleszar, Zofia; Schöls, Ludger; Just, Jennifer; Bauer, Peter; Torres Martin, Juan V; Kolb, Stefan

    2016-10-01

    Niemann-Pick disease type C (NP-C) is a rare multisystemic lysosomal disorder which, albeit treatable, is still starkly underdiagnosed. As NP-C features early onset ataxia (EOA) in 85-90 % of cases, EOA presents a promising target group for undiagnosed NP-C patients. Here, we assessed the ability of the previously established NP-C suspicion index (SI) and a novel abbreviated '2/3 SI' tool for rapid appraisal of suspected NP-C in unexplained EOA. This was a retrospective observational study comparing 'NP-C EOA' cases (EOA patients with confirmed NP-C) with non-NP-C EOA controls (EOA patients negative for NP-C gene mutations). NP-C risk prediction scores (RPS) from both the original and 2/3 SIs were calculated and their discriminatory performance evaluated. Among 133 patients (47 NP-C EOA cases; 86 non-NP-C EOA controls), moderate (40-69 points) and high (≥70 points) RPS were common based on original SI assessments in non-NP-C EOA controls [16 (19 %) and 8 (9 %), respectively], but scores ≥70 points were far more frequent [46 (98 %)] among NP-C EOA cases. RPS cut-off values provided 98 % sensitivity and 91 % specificity for NP-C at 70-point cut-off, and ROC analysis revealed an AUC of 0.982. Using the 2/3 SI, 90 % of NP-C EOA cases had scores of 2 or 3, and RPS analysis showed an AUC of 0.961. In conclusion, the NP-C SI and the new, quick-to-apply 2/3 SI distinguished well between NP-C and non-NP-C patients, even in EOA populations with high background levels of broadly NPC-compatible multisystemic disease features. While the original SI showed the greatest sensitivity, both tools reliably aided identification of patients with unexplained EOA who warranted further investigation for NP-C.

  20. Early Results of Chimney Technique for Type B Aortic Dissections Extending to the Aortic Arch

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Chen [Affiliated Hospital of Nantong University, Department of General Surgery (China); Tang, Hanfei; Qiao, Tong; Liu, Changjian; Zhou, Min, E-mail: 813477618@qq.com [The Affiliated Hospital of Nanjing University Medical School, Department of Vascular Surgery, Nanjing Drum Tower Hospital (China)

    2016-01-15

    ObjectiveTo summarize our early experience gained from the chimney technique for type B aortic dissection (TBAD) extending to the aortic arch and to evaluate the aortic remodeling in the follow-up period.MethodsFrom September 2011 to July 2014, 27 consecutive TBAD patients without adequate proximal landing zones were retrograde analyzed. Chimney stent-grafts were deployed parallel to the main endografts to reserve flow to branch vessels while extending the landing zones. In the follow-up period, aortic remodeling was observed with computed tomography angiography.ResultsThe technical success rate was 100 %, and endografts were deployed in zone 0 (n = 3, 11.1 %), zone 1 (n = 18, 66.7 %), and zone 2 (n = 6, 22.2 %). Immediately, proximal endoleaks were detected in 5 patients (18.5 %). During a mean follow-up period of 17.6 months, computed tomography angiography showed all the aortic stent-grafts and chimney grafts to be patent. Favorable remodeling was observed at the level of maximum descending aorta and left subclavian artery with expansion of true lumen (from 18.4 ± 4.8 to 25 ± 0.86 mm, p < 0.001 and 27.1 ± 0.62 to 28.5 ± 0.37 mm, p < 0.001) and depressurization of false lumen (from 23.7 ± 2.7 to 8.7 ± 3.8 mm, p < 0.001, from 5.3 ± 1.2 to 2.1 ± 2.1 mm, p < 0.001). While at the level of maximum abdominal aorta, suboptimal remodeling of the total aorta (from 24.1 ± 0.4 to 23.6 ± 1.5 mm, p = 0.06) and true lumen (from 13.8 ± 0.6 to 14.5 ± 0.4 mm, p = 0.08) was observed.ConclusionBased on our limited experience, the chimney technique with thoracic endovascular repair is demonstrated to be promising for TBAD extending to the arch with favorable aortic remodeling.

  1. Repetitive transcranial magnetic stimulation regulates L-type Ca(2+) channel activity inhibited by early sevoflurane exposure.

    Science.gov (United States)

    Liu, Yang; Yang, Huiyun; Tang, Xiaohong; Bai, Wenwen; Wang, Guolin; Tian, Xin

    2016-09-01

    Sevoflurane might be harmful to the developing brain. Therefore, it is essential to reverse sevoflurane-induced brain injury. This study aimed to determine whether low-frequency repetitive transcranial magnetic stimulation (rTMS) can regulate L-type Ca(2+) channel activity, which is inhibited by early sevoflurane exposure. Rats were randomly divided into three groups: control, sevoflurane, and rTMS groups. A Whole-cell patch clamp technique was applied to record L-type Ca(2+) channel currents. The I-V curve, steady-state activation and inactivation curves were studied in rats of each group at different ages (1 week, 2 weeks, 3 weeks, 4 weeks and 5 weeks old). In the control group, L-type Ca(2+) channel current density significantly increased from week 2 to week 3. Compared with the control group, L-type Ca(2+) channel currents of rats in the sevoflurane group were significantly inhibited from week 1 to week 3. Activation curves of L-type Ca(2+) channel shifted significantly towards depolarization at week 1 and week 2. Moreover, steady-state inactivation curves shifted towards hyperpolarization from week 1 to week 3. Compared with the sevoflurane group, rTMS significantly increased L-type Ca(2+) channel currents at week 2 and week 3. Activation curves of L-type Ca(2+) channel significantly shifted towards hyperpolarization at week 2. Meanwhile, steady-state inactivation curves significantly shifted towards depolarization at week 2. The period between week 2 and week 3 is critical for the development of L-type Ca(2+) channels. Early sevoflurane exposure inhibits L-type Ca(2+) channel activity and rTMS can regulate L-type Ca(2+) channel activity inhibited by sevoflurane. Copyright © 2016 Elsevier B.V. All rights reserved.

  2. Reduced prevalence of early preterm delivery in women with Type 1 diabetes and microalbuminuria--possible effect of early antihypertensive treatment during pregnancy

    DEFF Research Database (Denmark)

    Nielsen, L R; Kragh-Müller, Claus; Damm, P

    2006-01-01

    In normotensive women with Type 1 diabetes and microalbuminuria we previously found preterm delivery (Antihypertensive treatment was initiated in late pregnancy when preeclampsia was diagnosed and diastolic blood pressure > 90 mmHg. From April 2000 our routine...... was changed and early antihypertensive treatment with methyldopa was initiated if antihypertensive treatment was given prior to pregnancy, if urinary albumin excretion (UAE) was > 2 g/24 h, or blood pressure > 140/90 mmHg. The present study describes the impact of this more aggressive antiypertensive...... treatment in the prevalence of preterm delivery....

  3. Invasion by Ligustrum lucidum (Oleaceae in NW Argentina: early stage characteristics in different habitat types

    Directory of Open Access Journals (Sweden)

    Roxana Aragón

    2003-03-01

    Full Text Available Currently biological invasions are considered one of the world’s most serious conservation problems. Ligustrum lucidum is the most abundant exotic tree in secondary forest patches of montane forests of NW Argentina. We studied the determinants of success of the early stages of its life cycle in distinct habitat types, with the hope of identifying vulnerabilities that could be exploited to control the invasion. Seed arrival, germination, seedling recruitment and survival, and sapling growth were studied in edges, gaps and forest interior. Seed arrival was also assessed under perches and in open fields. Germination was studied in forest and grass-land patches. L. lucidum seedling survival and sapling growth were compared with the most abundant native species survival and growth. Seed arrival was strongly seasonal with a peak in mid-August. Seed rain did not differ significantly among habitat types, however there was a tendency for edges to receive more seeds when only dispersed seeds were considered. Perches strongly enhanced seed arrival; more than 40 times the number of seeds were dispersed beneath citrus plants (i.e. perches than found in paired open areas. In the forest, seeds in gaps and edges had higher germination rates, but there was no difference in seedling survival. Fruits under closed canopy exhibited the lowest germination. Germination and survival were low in open areas. Neither seedling recruitment nor sapling growth differed between gaps and forest interior. L. lucidum saplings grew significantly more than saplings of the most common native species, and also showed higher seedling survival. L. lucidum is a prolific fruit producer, is capable of germinating and surviving in a broad range of forest environments, it is relatively shade tolerant and has higher survival and faster growth rate in comprison to the most common native species. All these characteristics highlight its potency as a successful invader, and point to few

  4. Early Eocene rodents (Mammalia) from the Subathu Formation of type area (Himachal Pradesh), NW sub-Himalaya, India: Palaeobiogeographic implications

    Indian Academy of Sciences (India)

    Smita Gupta; Kishor Kumar

    2015-08-01

    Based on isolated upper cheek teeth, two new early Eocene rodents (Subathumys solanorius gen. et sp. nov. and Subathumys globulus gen. et sp. nov.) and three others (Birbalomys cf. sondaari, Birbalomys sp., cf. Chapattimys sp.) are recorded from the lower–middle part of the Subathu Formation of the type area in Himachal Pradesh, northwestern sub-Himalaya (India). The new rodents exhibit morphological features most similar to the unified ctenodactyloid family Chapattimyidae (including Yuomyidae), which is also represented in the assemblage from the upper part (middle Eocene) of the Subathu Formation. The associated lower cheek teeth are provisionally described as three indeterminate chapattimyid taxa. The new Subathu rodents are somewhat younger than the previously documented early Eocene assemblages from the Indian subcontinent, and are chronologically intermediate between the early Eocene ailuravines from Gujarat in the western peninsular India and the middle Eocene chapattimyids from northwestern India and Pakistan. They suggest that chapattimyids originated in the sub-Himalayan region during the Ypresian, which is earlier than previously believed. The absence of ailuravines in this as well as younger rodent assemblages from the subcontinent seems to suggest that ailuravines (Ischyromyidae), within a relatively short time after their appearance in the peninsular India in the early Eocene, may have been replaced by the indigenous chapattimyids. The co-occurrence in the early Eocene Subathu assemblage of three or more chapattimyids indicates their early radiation and dominance during the early and middle Eocene. This record of rodents opens the possibility of recovery of other small mammal remains in older levels of the Subathu Formation, which will be important for understanding linkage with early Eocene faunas from peninsular India, Europe and North America.

  5. Early type stars at high galactic latitudes II. Four evolved B-type stars of unusual chemical composition

    CERN Document Server

    Ramspeck, M; Edelmann, H

    2001-01-01

    We present the result of differential spectral analyses of a further four apparently normal B-type stars. Abundance anomalies (e.g. He, C, N enrichment), slow rotation and/or high gravities suggest that the programme stars are evolved low-mass B-type stars. In order to trace their evolutionary status several scenarios are discussed. Post-AGB evolution can be ruled out. PG 0229+064 and PG 1400+389 could be horizontal branch (HB) stars, while HD 76431 and SB 939 have already evolved away from the extreme HB (EHB). The low helium abundance of HD 76431 is consistent with post-EHB evolution. The enrichment in helium, carbon and nitrogen of the remaining stars can be explained either by deep mixing of nuclearly processed material to the surface or by diffusion processes modified by magnetic fields and/or stellar winds. A kinematic study of their galactic orbits indicates that the stars belong to an old disk population.

  6. Mutations in MODY Genes Are not Common Cause of Early-Onset Type 2 Diabetes in Mexican Families

    Directory of Open Access Journals (Sweden)

    Bravo-Ríos LE

    2005-05-01

    Full Text Available CONTEXT: Maturity-onset diabetes of the young (MODY is a monogenic form of diabetes mellitus characterized by autosomal dominant inheritance, early age of onset and a primary insulin secretion defect. Certain MODY gene sequence variants may be involved in polygenic forms of type 2 diabetes. OBJECTIVE: We assessed the contribution of MODY genes to the etiology of type 2 early-onset diabetes in 23 Mexican families, including five with apparently autosomal dominant inheritance. PATIENTS: Twenty-three unrelated Mexican families with early-onset type 2 diabetes previously screened for the presence of glucokinase mutations, were studied. DESIGN: We screened MODY genes for sequence variants by PCR-SSCP analysis and automated sequencing. We performed a functional analysis of the HNF-1alpha P379H recombinant protein in vitro in both HeLa and RINm5f beta-cell lines. MAIN OUTCOME MEASURES: MODY gene mutation screening and P379H mutant protein transactivation assay. RESULTS: No mutations were detected in the HNF-4alpha, IPF-1, NEUROD1 or HNF-1beta genes in any of the families studied. A new mutation (P379H of the HNF-1alpha gene was identified in one MODY family. RINm5f and HeLa cell transfection assays revealed decreased transactivation activity of the mutant protein on the human insulin promoter. CONCLUSIONS: All known MODY genes were screened for abnormalities in this cohort of early-onset diabetes families which included 5 MODY pedigrees. We identified a new HNF-1alpha MODY mutation (P379H and demonstrated that it reduces the transactivation potential of the mutant protein on the human insulin promoter. No other mutation was identified in this cohort indicating that abnormalities in MODY genes are generally not a common cause of early-onset diabetes and this includes MODY families in Mexico.

  7. The SLUGGS survey: revisiting the correlation between X-ray luminosity and total mass of massive early-type galaxies

    Science.gov (United States)

    Forbes, Duncan A.; Alabi, Adebusola; Romanowsky, Aaron J.; Kim, Dong-Woo; Brodie, Jean P.; Fabbiano, Giuseppina

    2017-01-01

    Here we utilize recent measures of galaxy total dynamical mass and X-ray gas luminosities (LX,Gas) for a sample of 29 massive early-type galaxies from the SLUGGS survey to probe LX, Gas-mass scaling relations. In particular, we investigate scalings with stellar mass, dynamical mass within 5 effective radii (Re) and total virial mass. We also compare these relations with predictions from Λ cold dark matter simulations. We find a strong linear relationship between LX, Gas and galaxy dynamical mass within 5Re, which is consistent with the recent cosmological simulations of Choi et al. that incorporate mechanical heating from AGN. We conclude that the gas surrounding massive early-type galaxies was shock-heated as it fell into collapsing dark matter haloes so that LX, Gas is primarily driven by the depth of a galaxy's potential well. Heating by an AGN plays an important secondary role in determining LX, Gas.

  8. Dark matter density profiles of the halos embedding early-type galaxies: characterizing halo contraction and dark matter annihilation strength

    CERN Document Server

    Chae, Kyu-Hyun; Frieman, Joshua A; Bernardi, Mariangela

    2012-01-01

    Identifying dark matter and characterizing its distribution in the inner region of halos embedding galaxies are inter-related problems of broad importance. We devise a new procedure of determining dark matter distribution in halos. We first make a self-consistent bivariate statistical match of stellar mass and velocity dispersion with halo mass as demonstrated here for the first time. Then, selecting early-type galaxy-halo systems we perform Jeans dynamical modeling with the aid of observed statistical properties of stellar mass profiles and velocity dispersion profiles. Dark matter density profiles derived specifically using Sloan Digital Sky Survey galaxies and halos from up-to-date cosmological dissipationless simulations deviate significantly from the dissipationless profle of Navarro-Frenk-White or Einasto in terms of inner density slope and/or concentration. From these dark matter profiles we find that dark matter density is enhanced in the inner region of most early-type galactic halos providing an ind...

  9. Academic Skills in Children with Early-Onset Type 1 Diabetes: The Effects of Diabetes-Related Risk Factors

    Science.gov (United States)

    Hannonen, Riitta; Komulainen, Jorma; Riikonen, Raili; Ahonen, Timo; Eklund, Kenneth; Tolvanen, Asko; Keskinen, Paivi; Nuuja, Anja

    2012-01-01

    Aim: The study aimed to assess the effects of diabetes-related risk factors, especially severe hypoglycaemia, on the academic skills of children with early-onset type 1 diabetes mellitus (T1DM). Method: The study comprised 63 children with T1DM (31 females, 32 males; mean age 9y 11mo, SD 4mo) and 92 comparison children without diabetes (40…

  10. The hELENa project - I. Stellar populations of early-type galaxies linked with local environment and galaxy mass

    Science.gov (United States)

    Sybilska, A.; Lisker, T.; Kuntschner, H.; Vazdekis, A.; van de Ven, G.; Peletier, R.; Falcón-Barroso, J.; Vijayaraghavan, R.; Janz, J.

    2017-09-01

    We present the first in a series of papers in The role of Environment in shaping Low-mass Early-type Nearby galaxies (hELENa) project. In this paper, we combine our sample of 20 low-mass early types (dEs) with 258 massive early types (ETGs) from the ATLAS3D survey - all observed with the SAURON integral field unit - to investigate early-type galaxies' stellar population scaling relations and the dependence of the population properties on local environment, extended to the low-σ regime of dEs. The ages in our sample show more scatter at lower σ values, indicative of less massive galaxies being affected by the environment to a higher degree. The shape of the age-σ relations for cluster versus non-cluster galaxies suggests that cluster environment speeds up the placing of galaxies on the red sequence. While the scaling relations are tighter for cluster than for the field/group objects, we find no evidence for a difference in average population characteristics of the two samples. We investigate the properties of our sample in the Virgo cluster as a function of number density (rather than simple clustrocentric distance) and find that dE ages correlate with the local density such that galaxies in regions of lower density are younger, likely because they are later arrivals to the cluster or have experienced less pre-processing in groups, and consequently used up their gas reservoir more recently. Overall, dE properties correlate more strongly with density than those of massive ETGs, which was expected as less massive galaxies are more susceptible to external influences.

  11. A near-infrared census of the multicomponent stellar structure of early-type dwarf galaxies in the Virgo cluster

    Energy Technology Data Exchange (ETDEWEB)

    Janz, J.; Laurikainen, E.; Salo, H. [Division of Astronomy, Department of Physics, P.O. Box 3000, FI-90014 University of Oulu (Finland); Lisker, T.; Hansson, K. S. A.; Meyer, H. T.; Paudel, S. [Astronomisches Rechen-Institut, Zentrum für Astronomie der Universität Heidelberg, Mönchhofstraße 12-14, D-69120 Heidelberg (Germany); Peletier, R. F.; Den Brok, M. [Kapteyn Astronomical Institute, University of Groningen, P.O. Box 800, 9700 AV Groningen (Netherlands); Niemi, S.-M. [Mullard Space Science Laboratory, University College London, Holmbury St. Mary, Dorking, Surrey RH5 6NT (United Kingdom); Toloba, E. [UCO/Lick Observatory, University of California, Santa Cruz, 1156 High Street, Santa Cruz, CA 95064 (United States); Hensler, G. [University of Vienna, Department of Astrophysics, Türkenschanzstraße 17, 1180 Vienna (Austria); Falcón-Barroso, J.; Ryś, A. [Instituto de Astrofísica de Canarias, Vía Láctea s/n, La Laguna, Tenerife (Spain); Boselli, A., E-mail: jjanz@ari.uni-heidelberg.de [CNRS, LAM (Laboratoire d' Astrophysique de Marseille) UMR 7326, Aix Marseille Université, F-13388 Marseille (France)

    2014-05-10

    The fraction of star-forming to quiescent dwarf galaxies varies from almost infinity in the field to zero in the centers of rich galaxy clusters. What is causing this pronounced morphology-density relation? What do quiescent dwarf galaxies look like when studied in detail, and what conclusions can be drawn about their formation mechanism? Here we study a nearly magnitude-complete sample (–19 < M{sub r} < –16 mag) of 121 Virgo cluster early types with deep near-infrared images from the SMAKCED project. We fit two-dimensional models with optional inner and outer components, as well as bar and lens components (in ∼15% of the galaxies), to the galaxy images. While a single Sérsic function may approximate the overall galaxy structure, it does not entirely capture the light distribution of two-thirds of our galaxies, for which multicomponent models provide a better fit. This fraction of complex galaxies shows a strong dependence on luminosity, being larger for brighter objects. We analyze the global and component-specific photometric scaling relations of early-type dwarf galaxies and discuss similarities with bright early and late types. The dwarfs' global galaxy parameters show scaling relations that are similar to those of bright disk galaxies. The inner components are mostly fitted with Sérsic n values close to 1. At a given magnitude, they are systematically larger than the bulges of spirals, suggesting that they are not ordinary bulges. We argue that the multicomponent structures in early-type dwarfs are mostly a phenomenon inherent to the disks and may indeed stem from environmental processing.

  12. Early Intervention of Didang Decoction on MLCK Signaling Pathways in Vascular Endothelial Cells of Type 2 Diabetic Rats

    Directory of Open Access Journals (Sweden)

    Shoujiao Ye

    2016-01-01

    Full Text Available In the study, type 2 diabetic rat model was established using streptozotocin (STZ combined with a high-fat diet, and the rats were divided into control and diabetic groups. Diabetic groups were further divided into nonintervening, simvastatin, Didang Decoction (DDD early-phase intervening, DDD mid-phase intervening, and DDD late-phase intervening groups. The expression level of MLCK was detected using Western Blot analysis, and the levels of cyclic adenosine monophosphate (cAMP, protein kinase C (PKC, and protein kinase A (PKA were examined using Real Time PCR. Under the electron microscope, the cells in the early-DDD-intervention group and the simvastatin group were significantly more continuous and compact than those in the diabetic group. Compared with the control group, the expression of cAMP-1 and PKA was decreased in all diabetic groups, whereas the expression of MLCK and PKC was increased in early- and mid-phase DDD-intervening groups (P<0.05; compared with the late-phase DDD-intervening group, the expression of cAMP-1 and PKA was higher, but the level of MLCK and PKC was lower in early-phase DDD-intervening group (P<0.05. In conclusion, the early use of DDD improves the permeability of vascular endothelial cells by regulating the MLCK signaling pathway.

  13. Expanding the Hygiene Hypothesis: Early Exposure to Infectious Agents Predicts Delayed-Type Hypersensitivity to Candida among Children in Kilimanjaro

    Science.gov (United States)

    Wander, Katherine; O'Connor, Kathleen; Shell-Duncan, Bettina

    2012-01-01

    Background Multiple lines of evidence suggest that infections in early life prevent the development of pathological immune responses to allergens and autoantigens (the hygiene hypothesis). Early infections may also affect later immune responses to pathogen antigen. Methods To evaluate an association between early infections and immune responses to pathogen antigen, delayed-type hypersensitivity (DTH) to Candida albicans was evaluated among 283 2- to 7-year-old children in Kilimanjaro, Tanzania. A questionnaire and physical examination were used to characterize variables reflecting early exposure to infectious agents (family size, house construction materials, BCG vaccination, hospitalization history). Logistic regression was used to evaluate the association between early exposure to infectious agents and DTH to C. albicans. Results Triceps skinfold thickness (OR: 1.11; 95% CI: 1.01, 1.22) and age (OR: 1.27; 95% CI: 1.04, 1.55) were positively associated with DTH to C. albicans. Adjusted for age and sex, large family size (OR: 2.81; 95% CI: 1.04, 7.61), BCG vaccination scar (OR: 3.10; 95% CI: 1.10, 8.71), and hospitalization during infancy with an infectious disease (OR: 4.67; 95% CI: 1.00, 21.74) were positively associated with DTH to C. albicans. Conclusions Early life infections were positively associated with later DTH to C. albicans. This result supports an expansion of the hygiene hypothesis to explain not only pathological immune responses to allergens, but also appropriate immune responses to pathogens. Immune system development may be responsive to early infections as an adaptive means to tailor reactivity to the local infectious disease ecology. PMID:22616000

  14. Discovery of a magnetic field in the early B-type star σ Lupi

    Science.gov (United States)

    Henrichs, H. F.; Kolenberg, K.; Plaggenborg, B.; Marsden, S. C.; Waite, I. A.; Landstreet, J. D.; Wade, G. A.; Grunhut, J. H.; Oksala, M. E.

    2012-09-01

    Context. Magnetic early B-type stars are rare. Indirect indicators are needed to identify them before investing in time-intensive spectropolarimetric observations. Aims: We use the strongest indirect indicator of a magnetic field in B stars, which is periodic variability of ultraviolet (UV) stellar wind lines occurring symmetric about the approximate rest wavelength. Our aim is to identify probable magnetic candidates which would become targets for follow-up spectropolarimetry to search for a magnetic field. Methods: From the UV wind line variability the B1/B2V star σ Lupi emerged as a new magnetic candidate star. AAT spectropolarimetric measurements with SEMPOL were obtained. The longitudinal component of the magnetic field integrated over the visible surface of the star was determined with the least-squares deconvolution method. Results: The UV line variations of σ Lupi are similar to what is known in magnetic B stars, but no periodicity could be determined. We detected a varying longitudinal magnetic field with amplitude of about 100 G with error bars of typically 20 G, which supports an oblique magnetic-rotator configuration. The equivalent width variations of the UV lines, the magnetic and the optical-line variations are consistent with the photometric period of 3.02 d, which we identify with the rotation period of the star. Additional observations with ESPaDOnS attached to the CFHT confirmed this discovery, and allowed the determination of a precise magnetic period. Analysis revealed that σ Lupi is a helium-strong star, with an enhanced nitrogen abundance and an underabundance of carbon, and has a chemically spotted surface. Conclusions.σ Lupi is a magnetic oblique rotator, and is a He-strong star. Like in other magnetic B stars the UV wind emission appears to originate close to the magnetic equatorial plane, with maximum emission occurring when a magnetic pole points towards the Earth. The 3.01972 ± 0.00043 d magnetic rotation period is consistent with

  15. ABOUT THE LINEARITY OF THE COLOR-MAGNITUDE RELATION OF EARLY-TYPE GALAXIES IN THE VIRGO CLUSTER

    Energy Technology Data Exchange (ETDEWEB)

    Smith Castelli, Analia V.; Faifer, Favio R. [Instituto de Astrofisica de La Plata (CCT-La Plata, CONICET-UNLP), Paseo del Bosque s/n, B1900FWA, La Plata (Argentina); Gonzalez, Nelida M. [Facultad de Ciencias Astronomicas y Geofisicas, Universidad Nacional de La Plata, Paseo del Bosque s/n, La Plata, B1900FWA (Argentina); Forte, Juan Carlos, E-mail: asmith@fcaglp.unlp.edu.ar, E-mail: ngonzalez@fcaglp.unlp.edu.ar, E-mail: favio@fcaglp.unlp.edu.ar, E-mail: forte@fcaglp.unlp.edu.ar [CONICET-Planetario de la Ciudad de Buenos Aires ' ' Galileo Galilei' ' , Av. Sarmiento y B. Roldan, Ciudad Autonoma de Buenos Aires (Argentina)

    2013-07-20

    We revisit the color-magnitude relation of Virgo Cluster early-type galaxies in order to explore its alleged nonlinearity. To this aim, we reanalyze the relation already published from data obtained within the ACS Virgo Cluster Survey of the Hubble Space Telescope and perform our own photometry and analysis of the images of 100 early-type galaxies observed as part of this survey. In addition, we compare our results with those reported in the literature from data of the Sloan Digital Sky Survey. We have found that when the brightest galaxies and untypical systems are excluded from the sample, a linear relation arises in agreement with what is observed in other groups and clusters. The central regions of the brightest galaxies also follow this relation. In addition, we notice that Virgo contains at least four compact elliptical galaxies besides the well-known object VCC 1297 (NGC 4486B). Their locations in the ({mu}{sub eff})-luminosity diagram define a trend different from that followed by normal early-type dwarf galaxies, setting an upper limit in effective surface brightness and a lower limit in the effective radius for their luminosities. Based on the distribution of different galaxy sub-samples in the color-magnitude and ({mu}{sub eff})-luminosity diagrams, we draw some conclusions on their formation and the history of their evolution.

  16. The Atlas3D project - XIX. The hot-gas content of early-type galaxies: fast versus slow rotators

    CERN Document Server

    Sarzi, Marc; Blitz, Leo; Bois, Maxime; Bournaud, Frederic; Bureau, M; Cappellari, Michele; Crocker, Alison F; Davies, Roger L; Davis, Timothy A; de Zeeuw, P T; Duc, Pierre-Alain; Khochfar, Sadegh; Krajnovic, Davor; Kuntschner, Harald; McDermid, Richard M; Morganti, Raffaella; Naab, Thorsten; Oosterloo, Tom; Scott, Nicholas; Serra, Paolo; Weijmans, Anne-Marie; Young, Lisa M

    2013-01-01

    For early-type galaxies, the ability to sustain a corona of hot, X-ray emitting gas could have played a key role in quenching their star-formation history. Yet, it is still unclear what drives the precise amount of hot gas around these galaxies. By combining photometric and spectroscopic measurements for the early-type galaxies observed during the Atlas3D integral-field survey with measurements of their X-ray luminosity based on X-ray data of both low and high spatial resolution we conclude that the hot-gas content of early-type galaxies can depend on their dynamical structure. Specifically, whereas slow rotators generally have X-ray halos with luminosity L_X,gas and temperature T values that are in line with what is expected if the hot-gas emission is sustained by the thermalisaton of the kinetic energy carried by the stellar-mass loss material, fast rotators tend to display L_X,gas values that fall consistently below the prediction of this model, with similar T values that do not scale with the stellar kine...

  17. The ATLAS3D project - XVII. Linking photometric and kinematic signatures of stellar discs in early-type galaxies

    CERN Document Server

    Krajnovic, Davor; Blitz, Leo; Bois, Maxime; Bournaud, Frederic; Bureau, Martin; Cappellari, Michele; Davies, Roger L; Davis, Timothy A; de Zeeuw, P T; Emsellem, Eric; Khochfar, Sadegh; Kuntschner, Harald; McDermid, Richard M; Morganti, Raffaella; Naab, Thorsten; Oosterloo, Tom; Sarzi, Marc; Scott, Nicholas; Serra, Paolo; Weijmans, Anne-Marie; Young, Lisa M

    2012-01-01

    [Abridged] We analyse the morphological structures in galaxies of the ATLAS3D sample by fitting a single Sersic profile and decomposing all non-barred objects (180 of 260 objects) in two components parameterised by an exponential and a general Sersic function. The aim of this analysis is to look for signatures of discs in light distributions of nearby early-type galaxies and compare them to kinematic properties. Using Sersic index from single component fits for a distinction between slow and fast rotators, or even late- and early-type galaxies, is not recommended. Assuming that objects with n>3 are slow rotators (or ellipticals), there is only a 22 per cent probability to correctly classify objects as slow rotators (or 37 per cent of previously classified as ellipticals). We show that exponential sub-components, as well as light profiles fitted with only a single component of a low Sersic index, can be linked with the kinematic evidence for discs in early-type galaxies. The median disk-to-total light ratio fo...

  18. Early-type dwarf galaxies with multicomponent stellar structure: Are they remnants of disc galaxies strongly transformed by their environment?

    CERN Document Server

    Aguerri, J Alfonso L

    2016-01-01

    The surface brightness distribution of $\\sim$30-40$\\%$ of the early-type dwarf galaxies with $-18 \\leq M_{B} \\leq -15$ in the Virgo and the Coma clusters is fitted by models that include two structural components (S\\`ersic + exponential) as for bright disc galaxies.The goal of the present study is to determine whether early-type dwarf galaxies with a two-component stellar structure in the Virgo and the Coma clusters are low-luminosity copies of bright disc galaxies or are the remnants of bright galaxies strongly transformed by cluster environmental effects.I analysed the location of bright disc galaxies and early-type dwarfs in the $r_{b,e}/h$- $n$ plane. The location in this plane of the two-component dwarf galaxies was compared with the remnants of tidally disrupted disc galaxies reported by numerical simulations. Bright unbarred disc galaxies show a strong correlation in the $r_{b,e}/h$-$n$ plane. Galaxies with larger S\\`ersic shape parameters show a higher $r_{b,e}/h$ ratio. In contrast, two-component ear...

  19. The Sloan Lens ACS Survey. VIII. The relation between environment and internal structure of early-type galaxies

    CERN Document Server

    Treu, T; Gorecki, A; Marshall, P J; Koopmans, L V E; Bolton, A S; Moustakas, L A; Burles, S

    2008-01-01

    We study the relation between the internal structure of early-type galaxies and their environment using 70 strong gravitational lenses from the Sloan ACS Lens Survey (SLACS). The Sloan Digital Sky Survey (SDSS) database is used to determine two measures of overdensity of galaxies around each lens: the projected number density of galaxies inside the tenth nearest neighbor (\\Sigma_{10}) and within a cone of radius one h^{-1} Mpc (D_1). Our main results are: 1) Lenses prefer overdense environments as expected for massive early-type galaxies (12/70 are in groups or clusters). 2) The distribution of overdensities is indistinguishable from that of ``twin'' non-lens galaxies selected from SDSS to have the same redshift and stellar velocity dispersion \\sigma_*. Thus, within our errors, lens galaxies are an unbiased population, and the SLACS results can be generalized to the overall population of early-type galaxies. 3) Typical contributions from external mass distribution are no more than a few per cent in local mass...

  20. The mass-discrepancy acceleration relation in early-type galaxies: extended mass profiles and the phantom menace to MOND

    CERN Document Server

    Janz, Joachim; Romanowsky, Aaron J; Ciotti, Luca; Alabi, Adebusola; Forbes, Duncan A

    2016-01-01

    The dark matter (DM) haloes around spiral galaxies appear to conspire with their baryonic content: empirically, significant amounts of DM are inferred only below a universal characteristic acceleration scale. Moreover, the discrepancy between the baryonic and dynamical mass, which is usually interpreted as the presence of DM, follows a very tight mass discrepancy acceleration (MDA) relation. Its universality, and its tightness in spiral galaxies, poses a challenge for the DM interpretation and was used to argue in favour of MOdified Newtonian Dynamics (MOND). Here, we test whether or not this applies to early-type galaxies. We use the dynamical models of fast-rotator early-type galaxies by Cappellari et al. based on ATLAS$^{3D}$ and SLUGGS data, which was the first homogenous study of this kind, reaching ~4 $R_e$, where DM begins to dominate the total mass budget. We find the early-type galaxies to follow a MDA relation similar to spiral galaxies, but systematically offset. Also, while the slopes of the mass ...

  1. The Evolution and Structure of Early-type Field Galaxies: A Combined Statistical Analysis of Gravitational Lenses

    CERN Document Server

    Rusin, D

    2004-01-01

    We introduce a framework for simultaneously investigating the structure and luminosity evolution of early-type gravitational lens galaxies. The method is based on the fundamental plane, which we interpret using the aperture mass-radius relations derived from lensed image geometries. We apply this method to our previous sample of 22 lens galaxies with measured redshifts and excellent photometry. Modeling the population with a single mass profile and evolutionary history, we find that early-type galaxies are nearly isothermal (logarithmic density slope n = 2.06 +/- 0.17, 68% C.L.), and that their stars evolve at a rate of dlog(M/L)_B/dz = -0.50 +/- 0.19 (68% C.L.) in the rest frame B band. For a Salpeter IMF and a concordance cosmology, this implies a mean star formation redshift of > 1.5 at 95% confidence. While this model can neatly describe the mean properties of early-type galaxies, it is clear that the scatter of the lens sample is too large to be explained by observational uncertainties alone. We therefo...

  2. THE MYSTERY OF THE σ-BUMP—A NEW SIGNATURE FOR MAJOR MERGERS IN EARLY-TYPE GALAXIES?

    Energy Technology Data Exchange (ETDEWEB)

    Schauer, Anna Therese Phoebe; Remus, Rhea-Silvia; Burkert, Andreas [Universitäts-Sternwarte München, Scheinerstrasse 1, D-81679 München (Germany); Johansson, Peter H., E-mail: aschauer@usm.uni-muenchen.de [Department of Physics, University of Helsinki, Gustaf Hällströmin katu 2a, FI-00014 Helsinki (Finland)

    2014-03-10

    The stellar velocity dispersion as a function of the galactocentric radius of an early-type galaxy can generally be well approximated by a power law σ∝r {sup β}. However, some observed dispersion profiles show a deviation from this fit at intermediate radii, usually between one and three R {sub eff}, where the velocity dispersion remains constant with radius, showing a bump-like behavior, which we term the {sup σ-}bump. To understand the origin of this σ-bump, we study a set of simulated early-type galaxies formed in major mergers. We find the σ-bump in all of our simulated early-type galaxies, with the size and position of the bump slightly varying from galaxy to galaxy, suggesting that the bump is a characteristic of the major merger formation scenario. The feature can be seen both in the intrinsic and projected stellar velocity dispersions. In contrast to shells that form during the merger event but evolve with time and finally disappear, the σ-bump stays nearly constant with radius and is a permanent feature that is preserved until the end of the simulation. The σ-bump is not seen in the dark matter and gas components and we therefore conclude that it is a purely stellar feature of merger remnants.

  3. Formation and evolution of dwarf early-type galaxies in the Virgo cluster II. Kinematic Scaling Relations

    CERN Document Server

    Toloba, E; Peletier, R; Falcon-Barroso, J; van de Ven, G; Gorgas, J

    2012-01-01

    We place our sample of 18 Virgo dwarf early-type galaxies (dEs) on the V-K - velocity dispersion, Faber-Jackson, and Fundamental Plane (FP) scaling relations for massive early-type galaxies (Es). We use a generalized velocity dispersion, which includes rotation, to be able to compare the location of both rotationally and pressure supported dEs with those of early and late-type galaxies. We find that dEs seem to bend the Faber-Jackson relation of Es to lower velocity dispersions, being the link between Es and dwarf spheroidal galaxies (dSphs). Regarding the FP relation, we find that dEs are significantly offset with respect to massive hot stellar systems, and re-casting the FP into the so-called kappa-space suggests that this offset is related to dEs having a total mass-to-light ratio higher than Es but still significantly lower than dSph galaxies. Given a stellar mass-to-light ratio based on the measured line indices of dEs, the FP offset allows us to infer that the dark matter fraction within the half light ...

  4. Explaining the reportedly over-massive black holes in early-type galaxies with intermediate-scale discs

    CERN Document Server

    Savorgnan, Giulia A D

    2015-01-01

    The classification "early-type" galaxy includes both elliptically- and lenticular-shaped galaxies. Theoretically, the spheroid-to-disc flux ratio of an early-type galaxy can assume any positive value, but in practice studies often consider only spheroid/disc decompositions in which the disc neatly dominates over the spheroid at large galaxy radii, creating an inner "bulge" as observed in most spiral galaxies. Here we show that decompositions in which the disc remains embedded within the spheroid, labelled by some as "unphysical", correctly reproduce both the photometric and kinematic properties of early-type galaxies with intermediate-scale discs. Intermediate-scale discs have often been confused with large-scale discs and incorrectly modelled as such; when this happens, the spheroid luminosity is considerably underestimated. This has recently led to some surprising conclusions, such as the claim that a number of galaxies with intermediate-scale discs (Mrk 1216, NGC 1277, NGC 1271, and NGC 1332) host a centra...

  5. The ATLAS(3D) project : II. Morphologies, kinemetric features and alignment between photometric and kinematic axes of early-type galaxies

    NARCIS (Netherlands)

    Krajnovic, Davor; Emsellem, Eric; Cappellari, Michele; Alatalo, Katherine; Blitz, Leo; Bois, Maxime; Bournaud, Frederic; Bureau, Martin; Davies, Roger L.; Davis, Timothy A.; de Zeeuw, P. T.; Khochfar, Sadegh; Kuntschner, Harald; Lablanche, Pierre-Yves; McDermid, Richard M.; Morganti, Raffaella; Naab, Thorsten; Oosterloo, Tom; Sarzi, Marc; Scott, Nicholas; Serra, Paolo; Weijmans, Anne-Marie; Young, Lisa M.

    2011-01-01

    We use the ATLAS(3D) sample of 260 early-type galaxies to study the apparent kinematic misalignment angle, Psi, defined as the angle between the photometric and kinematic major axes. We find that 71 per cent of nearby early-type galaxies are strictly aligned systems (Psi

  6. The 3' region of Human Papillomavirus type 16 early mRNAs decrease expression

    DEFF Research Database (Denmark)

    Vinther, J.; Rosenstierne, M.W.; Kristiansen, Karen

    2005-01-01

    of the reporter mRNAs. The integrity of the reporter mRNAs were tested by northern blotting. Results: We show that the 3' region of the HPV-16 early mRNAs ( HPV-16 nucleotide (nt.) 2582 4214) act in cis to decrease both mRNA and protein levels. This region seems to affect transcription from the exogenous minimal...

  7. Identification and predicting short-term prognosis of early cardiorenal syndrome type 1: KDIGO is superior to RIFLE or AKIN.

    Directory of Open Access Journals (Sweden)

    Zhilian Li

    Full Text Available OBJECTIVE: Acute kidney injury (AKI in patients hospitalized for acute heart failure (AHF is usually type 1 of the cardiorenal syndrome (CRS and has been associated with increased morbidity and mortality. Early recognition of AKI is critical. This study was to determine if the new KDIGO criteria (Kidney Disease: Improving Global Outcomes for identification and short-term prognosis of early CRS type 1 was superior to the previous RIFLE and AKIN criteria. METHODS: The association between AKI diagnosed by KDIGO but not by RIFLE or AKIN and in-hospital mortality was retrospectively evaluated in 1005 Chinese adult patients with AHF between July 2008 and May 2012. AKI was defined as RIFLE, AKIN and KDIGO criteria, respectively. Cox regression was used for multivariate analysis of in-hospital mortality. RESULTS: Within 7 days on admission, the incidence of CRS type 1 was 38.9% by KDIGO criteria, 34.7% by AKIN, and 32.1% by RIFLE. A total of 110 (10.9% cases were additional diagnosed by KDIGO criteria but not by RIFLE or AKIN. 89.1% of them were in Stage 1 (AKIN or Stage Risk (RIFLE. They accounted for 18.4% (25 cases of the overall death. After adjustment, this proportion remained an independent risk factor for in-hospital mortality [odds ratios (OR3.24, 95% confidence interval(95%CI 1.97-5.35]. Kaplan-Meier curve showed AKI patients by RIFLE, AKIN, KDIGO and [K(+R(-+K(+A(-] had lower hospital survival than non-AKI patients (Log Rank P<0.001. CONCLUSION: KDIGO criteria identified significantly more CRS type 1 episodes than RIFLE or AKIN. AKI missed diagnosed by RIFLE or AKIN criteria was an independent risk factor for in-hospital mortality, indicating the new KDIGO criteria was superior to RIFLE and AKIN in predicting short-term outcomes in early CRS type 1.

  8. Virion component of herpes simplex virus type 1 KOS interferes with early shutoff of host protein synthesis induced by herpes simplex virus type 2 186.

    OpenAIRE

    Hill, T M; Sadler, J R; Betz, J L

    1985-01-01

    Herpes simplex virus (HSV) strains HSV type 1 (HSV-1) KOS and HSV-2 186 are representative of delayed and early shutoff strains, respectively, with regard to their ability to inhibit protein synthesis in Friend erythroleukemia cells. When these cells were simultaneously infected with HSV-1 KOS and HSV-2 186, HSV-1 KOS interfered with the rapid suppression of globin synthesis induced by HSV-2 186. The observed interference was competitive and not due to exclusion of HSV-2 by HSV-1 at the level...

  9. THE ORIGIN OF DUST IN EARLY-TYPE GALAXIES AND IMPLICATIONS FOR ACCRETION ONTO SUPERMASSIVE BLACK HOLES

    Energy Technology Data Exchange (ETDEWEB)

    Martini, Paul [Department of Astronomy and Center for Cosmology and Astroparticle Physics, The Ohio State University, Columbus, OH 43210 (United States); Dicken, Daniel [Institut de Astrophysique Spatiale, Paris (France); Storchi-Bergmann, Thaisa [Instituto de Fisica, Universidade Federal do Rio Grande do Sul, Av. Bento Goncalves 9500, Caixa Postal 15051, 91501-970 Porto Alegre, RS (Brazil)

    2013-04-01

    We have conducted an archival Spitzer study of 38 early-type galaxies in order to determine the origin of the dust in approximately half of this population. Our sample galaxies generally have good wavelength coverage from 3.6 {mu}m to 160 {mu}m, as well as visible-wavelength Hubble Space Telescope (HST) images. We use the Spitzer data to estimate dust masses, or establish upper limits, and find that all of the early-type galaxies with dust lanes in the HST data are detected in all of the Spitzer bands and have dust masses of {approx}10{sup 5}-10{sup 6.5} M{sub Sun }, while galaxies without dust lanes are not detected at 70 {mu}m and 160 {mu}m and typically have <10{sup 5} M{sub Sun} of dust. The apparently dust-free galaxies do have 24 {mu}m emission that scales with the shorter-wavelength flux, yet substantially exceeds the expectations of photospheric emission by approximately a factor of three. We conclude this emission is dominated by hot, circumstellar dust around evolved stars that does not survive to form a substantial interstellar component. The order-of-magnitude variations in dust masses between galaxies with similar stellar populations rule out a substantial contribution from continual, internal production in spite of the clear evidence for circumstellar dust. We demonstrate that the interstellar dust is not due to purely external accretion, unless the product of the merger rate of dusty satellites and the dust lifetime is at least an order of magnitude higher than expected. We propose that dust in early-type galaxies is seeded by external accretion, yet the accreted dust is maintained by continued growth in externally accreted cold gas beyond the nominal lifetime of individual grains. The several Gyr depletion time of the cold gas is long enough to reconcile the fraction of dusty early-type galaxies with the merger rate of gas-rich satellites. As the majority of dusty early-type galaxies are also low-luminosity active galactic nuclei and likely fueled

  10. Early Correlates of Preschool Aggressive Behavior According to Type of Aggression and Measurement

    Science.gov (United States)

    Juliano, Mariel; Stetson Werner, Rebecca; Wright Cassidy, Kimberly

    2006-01-01

    This study investigated both relational and physical aggression in preschool children, explored potential differences in informant reporting and child sex on these subtypes, and examined relationships between types of aggressive behaviors and other types of negative and positive social behaviors. Naturalistic observations of social behavior,…

  11. Serum levels of advanced glycation endproducts and other markers of protein damage in early diabetic nephropathy in type 1 diabetes.

    Directory of Open Access Journals (Sweden)

    Bruce A Perkins

    Full Text Available OBJECTIVE: To determine the role of markers of plasma protein damage by glycation, oxidation and nitration in microalbuminuria onset or subsequent decline of glomerular filtration rate (termed "early GFR decline" in patients with type 1 diabetes. METHODS: From the 1(st Joslin Kidney Study, we selected 30 patients with longstanding normoalbuminuria and 55 patients with new onset microalbuminuria. Patients with microalbuminuria had 8-12 years follow-up during which 33 had stable GFR and 22 early GFR decline. Mean baseline GFR(CYSTATIN C was similar between the three groups. Glycation, oxidation and nitration markers were measured in protein and ultrafiltrate at baseline by liquid chromatography-tandem mass spectrometry using the most reliable methods currently available. RESULTS: Though none were significantly different between patients with microalbuminuria with stable or early GFR decline, levels of 6 protein damage adduct residues of plasma protein and 4 related free adducts of plasma ultrafiltrate were significantly different in patients with microalbuminuria compared to normoalbuminuria controls. Three protein damage adduct residues were decreased and 3 increased in microalbuminuria while 3 free adducts were decreased and one increased in microalbuminuria. The most profound differences were of N-formylkynurenine (NFK protein adduct residue and N(ω-carboxymethylarginine (CMA free adduct in which levels were markedly lower in microalbuminuria (P<0.001 for both. CONCLUSIONS: Complex processes influence levels of plasma protein damage and related proteolysis product free adducts in type 1 diabetes and microalbuminuria. The effects observed point to the possibility that patients who have efficient mechanisms of disposal of damaged proteins might be at an increased risk of developing microalbuminuria but not early renal function decline. The findings support the concept that the mechanisms responsible for microalbuminuria may differ from the

  12. Trace elements in early phase type 2 diabetes mellitus-A population-based study. The HUNT study in Norway.

    Science.gov (United States)

    Hansen, Ailin Falkmo; Simić, Anica; Åsvold, Bjørn Olav; Romundstad, Pål Richard; Midthjell, Kristian; Syversen, Tore; Flaten, Trond Peder

    2017-03-01

    Differences in trace elements levels between individuals with type 2 diabetes and controls have been reported in several studies in various body fluids and tissues, but results have been inconsistent. In order to examine trace element levels in the early phase of type 2 diabetes, we investigated the association between whole blood levels of 26 trace elements and the prevalence of previously undiagnosed, screening-detected type 2 diabetes. The study was conducted as a case-control study nested within the third survey of the population-based Nord-Trøndelag Health Study (HUNT3 Survey). Among participants without previously known diabetes, 128 cases of type 2 diabetes were diagnosed in people with a high diabetes risk score (FINDRISC≥15), and frequency-matched for age and sex with 755 controls. Blood samples were analyzed by high resolution inductively coupled plasma mass spectrometry. Associations between trace element levels and the prevalence of previously undiagnosed type 2 diabetes were evaluated with multivariable conditional logistic regression controlling for age, sex, body mass index, waist-to-hip ratio, education, income, smoking and family history of diabetes. The prevalence of previously undiagnosed type 2 diabetes increased across tertiles/quartiles for cadmium, chromium, iron, nickel, silver and zinc, and decreased with increasing quartiles of bromine (Ptrendzinc in the development of type 2 diabetes.

  13. Dynamic cerebral autoregulatory capacity is affected early in Type 2 diabetes

    DEFF Research Database (Denmark)

    Kim, Y.S.; Immink, R.V.; Stok, W.J.

    2008-01-01

    Type 2 diabetes is associated with an increased risk of endothelial dysfunction and microvascular complications with impaired autoregulation of tissue perfusion. Both microvascular disease and cardiovascular autonomic neuropathy may affect cerebral autoregulation. In the present study, we tested...... the hypothesis that, in the absence of cardiovascular autonomic neuropathy, cerebral autoregulation is impaired in subjects with DM+ (Type 2 diabetes with microvascular complications) but intact in subjects with DM- (Type 2 diabetes without microvascular complications). Dynamic cerebral autoregulation......, -15+/-6% in subjects with DM- and -15+/-7% in subjects with DM+). HbA(1c) (glycated haemoglobin) and the duration of diabetes, but not blood pressure, were determinants of transfer function phase. In conclusion, dysfunction of dynamic cerebral autoregulation in subjects with Type 2 diabetes appears...

  14. The VIRTUE Registry of type B thoracic dissections--study design and early results

    DEFF Research Database (Denmark)

    2011-01-01

    Endovascular procedures for repair of Type B aortic dissection have become increasingly common and are often considered to be first line therapy for acute complicated dissections. The long term durability of these repairs is largely undefined....

  15. Identification and predicting short-term prognosis of early cardiorenal syndrome type 1: KDIGO is superior to RIFLE or AKIN.

    Science.gov (United States)

    Li, Zhilian; Cai, Lu; Liang, Xinling; Du, Zhiming; Chen, Yuanhan; An, Shengli; Tan, Ning; Xu, Lixia; Li, Ruizhao; Li, Liwen; Shi, Wei

    2014-01-01

    Acute kidney injury (AKI) in patients hospitalized for acute heart failure (AHF) is usually type 1 of the cardiorenal syndrome (CRS) and has been associated with increased morbidity and mortality. Early recognition of AKI is critical. This study was to determine if the new KDIGO criteria (Kidney Disease: Improving Global Outcomes) for identification and short-term prognosis of early CRS type 1 was superior to the previous RIFLE and AKIN criteria. The association between AKI diagnosed by KDIGO but not by RIFLE or AKIN and in-hospital mortality was retrospectively evaluated in 1005 Chinese adult patients with AHF between July 2008 and May 2012. AKI was defined as RIFLE, AKIN and KDIGO criteria, respectively. Cox regression was used for multivariate analysis of in-hospital mortality. Within 7 days on admission, the incidence of CRS type 1 was 38.9% by KDIGO criteria, 34.7% by AKIN, and 32.1% by RIFLE. A total of 110 (10.9%) cases were additional diagnosed by KDIGO criteria but not by RIFLE or AKIN. 89.1% of them were in Stage 1 (AKIN) or Stage Risk (RIFLE). They accounted for 18.4% (25 cases) of the overall death. After adjustment, this proportion remained an independent risk factor for in-hospital mortality [odds ratios (OR)3.24, 95% confidence interval(95%CI) 1.97-5.35]. Kaplan-Meier curve showed AKI patients by RIFLE, AKIN, KDIGO and [K(+)R(-)+K(+)A(-)] had lower hospital survival than non-AKI patients (Log Rank PRIFLE or AKIN. AKI missed diagnosed by RIFLE or AKIN criteria was an independent risk factor for in-hospital mortality, indicating the new KDIGO criteria was superior to RIFLE and AKIN in predicting short-term outcomes in early CRS type 1.

  16. A Panchromatic Catalog of Early-type Galaxies at Intermediate Redshift in the Hubble Space Telescope Wide Field Camera 3 Early Release Science Field

    Science.gov (United States)

    Rutkowski, M. J.; Cohen, S. H.; Kaviraj, S.; O'Connell, R. W.; Hathi, N. P.; Windhorst, R. A.; Ryan, R. E., Jr.; Crockett, R. M.; Yan, H.; Kimble, R. A.; Silk, J.; McCarthy, P. J.; Koekemoer, A.; Balick, B.; Bond, H. E.; Calzetti, D.; Disney, M. J.; Dopita, M. A.; Frogel, J. A.; Hall, D. N. B.; Holtzman, J. A.; Paresce, F.; Saha, A.; Trauger, J. T.; Walker, A. R.; Whitmore, B. C.; Young, E. T.

    2012-03-01

    In the first of a series of forthcoming publications, we present a panchromatic catalog of 102 visually selected early-type galaxies (ETGs) from observations in the Early Release Science (ERS) program with the Wide Field Camera 3 (WFC3) on the Hubble Space Telescope (HST) of the Great Observatories Origins Deep Survey-South (GOODS-S) field. Our ETGs span a large redshift range, 0.35 lsim z lsim 1.5, with each redshift spectroscopically confirmed by previous published surveys of the ERS field. We combine our measured WFC3 ERS and Advanced Camera for Surveys (ACS) GOODS-S photometry to gain continuous sensitivity from the rest-frame far-UV to near-IR emission for each ETG. The superior spatial resolution of the HST over this panchromatic baseline allows us to classify the ETGs by their small-scale internal structures, as well as their local environment. By fitting stellar population spectral templates to the broadband photometry of the ETGs, we determine that the average masses of the ETGs are comparable to the characteristic stellar mass of massive galaxies, 1011 publications which address the diversity of stellar populations likely to be present in these ETGs, and the potential mechanisms by which recent star formation episodes are activated, are discussed.

  17. A Panchromatic Catalog of Early-Type Galaxies at Intermediate Redshift in the Hubble Space Telescope Wide Field Camera 3 Early Release Science Field

    CERN Document Server

    Rutkowski, M J; Kaviraj, S; O'Connell, R W; Hathi, N P; Windhorst, R A; Ryan, R E; Crockett, R M; Yan, H; Kimble, R A; Silk, J; McCarthy, P J; Koekemoer, A; Balick, B; Bond, H E; Calzetti, D; Disney, M J; Dopita, M A; Frogel, J A; Hall, D N B; Holtzman, J A; Paresce, F; Saha, A; Trauger, J T; Walker, A R; Whitmore, B C; Young, E T

    2012-01-01

    In the first of a series of forthcoming publications, we present a panchromatic catalog of 102 visually-selected early-type galaxies (ETGs) from observations in the Early Release Science (ERS) program with the Wide Field Camera 3 (WFC3) on the Hubble Space Telescope (HST) of the Great Observatories Origins Deep Survey-South (GOODS-S) field. Our ETGs span a large redshift range, 0.35 < z < 1.5, with each redshift spectroscopically-confirmed by previous published surveys of the ERS field. We combine our measured WFC3 ERS and ACS GOODS-S photometry to gain continuous sensitivity from the rest-frame far-UV to near-IR emission for each ETG. The superior spatial resolution of the HST over this panchromatic baseline allows us to classify the ETGs by their small-scale internal structures, as well as their local environment. By fitting stellar population spectral templates to the broad-band photometry of the ETGs, we determine that the average masses of the ETGs are comparable to the characteristic stellar mass ...

  18. The type I interferon signature in leukocyte subsets from peripheral blood of patients with early arthritis: a major contribution by granulocytes

    OpenAIRE

    2016-01-01

    Background The type I interferon (IFN) signature in rheumatoid arthritis (RA) has shown clinical relevance in relation to disease onset and therapeutic response. Identification of the cell type(s) contributing to this IFN signature could provide insight into the signature’s functional consequences. The aim of this study was to investigate the contribution of peripheral leukocyte subsets to the IFN signature in early arthritis. Methods Blood was collected from 26 patients with early arthritis ...

  19. EARLY ULTRAVIOLET/OPTICAL EMISSION OF THE TYPE Ib SN 2008D

    Energy Technology Data Exchange (ETDEWEB)

    Bersten, Melina C.; Nomoto, Ken' ichi [Kavli Institute for the Physics and Mathematics of the Universe, Todai Institutes for Advanced Study, University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8583 (Japan); Tanaka, Masaomi [National Astronomical Observatory of Japan, 2-21-1 Osawa, Mitaka, Tokyo 181-8588 (Japan); Tominaga, Nozomu [Department of Physics, Faculty of Science and Engineering, Konan University, 8-9-1 Okamoto, Kobe, Hyogo 658-8501 (Japan); Benvenuto, Omar G., E-mail: melina.bersten@ipmu.jp [Facultad de Ciencias Astronomicas y Geofisicas, Universidad Nacional de La Plata, Paseo del Bosque S/N, B1900FWA La Plata (Argentina)

    2013-04-20

    We propose an alternative explanation for the post-breakout emission of SN 2008D associated with the X-ray transient 080109. Observations of this object show a very small contrast of 0.35 dex between the light-curve minimum occurring soon after the breakout, and the main luminosity peak which is due to radioactive heating of the ejecta. Hydrodynamical models show that the cooling of a shocked Wolf-Rayet star leads to a much greater difference ({approx}> 0.9 dex). Our proposed scenario is that of a jet produced during the explosion which deposits {sup 56}Ni-rich material in the outer layers of the ejecta. The presence of high-velocity radioactive material allows us to reproduce the complete luminosity evolution of the object. Without outer {sup 56}Ni it could be possible to reproduce the early emission purely from cooling of the shocked envelope by assuming a larger progenitor than a Wolf-Rayet star, but that would require an initial density structure significantly different from what is predicted by stellar evolution models. Analytic models of the cooling phase have been proposed reproduce the early emission of SN 2008D with an extended progenitor. However, we found that the models are valid only until 1.5 days after the explosion where only two data of SN 2008D are available. We also discuss the possibility of the interaction of the ejecta with a binary companion, based on published analytic expressions. However, the binary separation required to fit the early emission should be {approx}< 3 R{sub Sun }, which is too small for a system containing two massive stars.

  20. Phenotype variability and early onset ataxia symptoms in spinocerebellar ataxia type 7: comparison and correlation with other spinocerebellar ataxias

    Directory of Open Access Journals (Sweden)

    Marcus Vinicius Cristino de Albuquerque

    2015-01-01

    Full Text Available The spinocerebellar ataxias (SCA are a group of neurodegenerative disorders characterized by heterogeneous clinical presentation. Spinocerebellar ataxia type 7 (SCA7 is caused by an abnormal CAG repeat expansion and includes cerebellar signs associated with visual loss and ophthalmoplegia. Marked anticipation and dynamic mutation is observed in SCA7. Moreover, phenotype variability and very early onset of symptoms may occur. In this article, a large series of Brazilian patients with different SCA subtypes was evaluated, and we compared the age of onset of SCA7 with other SCA. From the 26 patients with SCA7, 4 manifested their symptoms before 10-year-old. Also, occasionally the parents may have the onset of symptoms after their children. In conclusion, our study highlights the genetic anticipation phenomenon that occurs in SCA7 families. Patients with very early onset ataxia in the context of a remarkable family history, must be considered and tested for SCA7.

  1. Phenotype variability and early onset ataxia symptoms in spinocerebellar ataxia type 7: comparison and correlation with other spinocerebellar ataxias.

    Science.gov (United States)

    Albuquerque, Marcus Vinicius Cristino de; Pedroso, José Luiz; Braga Neto, Pedro; Barsottini, Orlando Graziani Povoas

    2015-01-01

    The spinocerebellar ataxias (SCA) are a group of neurodegenerative disorders characterized by heterogeneous clinical presentation. Spinocerebellar ataxia type 7 (SCA7) is caused by an abnormal CAG repeat expansion and includes cerebellar signs associated with visual loss and ophthalmoplegia. Marked anticipation and dynamic mutation is observed in SCA7. Moreover, phenotype variability and very early onset of symptoms may occur. In this article, a large series of Brazilian patients with different SCA subtypes was evaluated, and we compared the age of onset of SCA7 with other SCA. From the 26 patients with SCA7, 4 manifested their symptoms before 10-year-old. Also, occasionally the parents may have the onset of symptoms after their children. In conclusion, our study highlights the genetic anticipation phenomenon that occurs in SCA7 families. Patients with very early onset ataxia in the context of a remarkable family history, must be considered and tested for SCA7.

  2. Effect of Somatic Cell Types and Culture Medium on in vitro Maturation, Fertilization and Early Development Capability of Buffalo Oocytes

    Directory of Open Access Journals (Sweden)

    H. Jamil*, H. A. Samad, N. Rehman, Z. I. Qureshi and L. A. Lodhi

    2011-04-01

    Full Text Available This study was designed to evaluate the efficacy of different somatic cell types and media in supporting in vitro maturation (IVM, in vitro fertilization (IVF and early embryonic development competence of buffalo follicular oocytes. Cumulus oocyte complexes were collected for maturation from follicles (>6mm of buffalo ovaries collected at the local abattoir. Oocytes were co-cultured in tissue culture medium (TCM-199 with either granulosa cells, cumulus cells, or buffalo oviductal epithelial cells (BOEC @ 3x106 cells/ml or in TCM-199 without helper cells (control at 39°C and 5%CO2 in humidified air. Fresh semen was prepared in modified Ca++ free Tyrode medium. Fertilization was carried out in four types of media: i Tyrode lactate albumin pyruvate (TALP, ii TALP+BOEC, iii modified Ca++ free Tyrode and iv modified Ca++ free Tyrode+BOEC. Fertilized oocytes were cultured for early embryonic development in TCM-199 with and without BOEC. Higher maturation rates were observed in the granulosa (84.24% and cumulus cells (83.44% than BOEC co culture system (73.37%. Highest fertilization rate was obtained in modified Ca++ free Tyrode with BOEC co culture (70.42%, followed by modified Ca++ free Tyrode alone (63.77%, TALP with BOEC (36.92% and TALP alone (10.94%. Development of early embryos (8-cell stage improved in TCM-199 with BOEC co culture than TCM-199 alone. From the results of this study, it can be concluded that addition of somatic cells (granulosa cells, cumulus cells results in higher maturation rates of buffalo follicular oocytes than BOEC co culture system, while fertilization rate improved in modified Ca++ free Tyrode with and without BOEC. Addition of BOEC to TCM-199 improved the developmental capacity of early embryo.

  3. Intraoperative and early postoperative flap-related complications of laser in situ keratomileusis using two types of Moria microkeratomes.

    Science.gov (United States)

    Karabela, Yunus; Muftuoglu, Orkun; Gulkilik, Ibrahim Gokhan; Kocabora, Mehmet Selim; Ozsutcu, Mustafa

    2014-10-01

    The purpose of this study is to describe the incidence, management, and visual outcomes of intraoperative and early postoperative flap-related complications of laser in situ keratomileusis (LASIK) surgery using two types of Moria M2 microkeratomes. This retrospective analysis was performed on 806 primary LASIK cases. The intraoperative and early postoperative flap-related complications were identified and categorized according to type of Moria microkeratome. There were 52 intraoperative and early postoperative complications--one case of partial flap (0.124 %), one case of free flap (0.124 %), one case of small flap (0.124 %), 13 cases of epithelial defect (1.61 %), 12 cases of flap striae (1.49 %), 10 cases of diffuse lamellar keratitis (1.24 %), 10 cases of interface debris (1.24 %), three cases of epithelial ingrowth (0.37 %), and one case of microbial infection (0.124 %). The overall incidence of flap complications was 6.45 %. There were 27 right eye (6.73 %) and 25 left eye (6.17 %) complications. The incidence of complications with the Moria automated metallic head 130 microkeratome was 4.22 % and with the Moria single-use head 90 microkeratome was 2.23 %. We observed one culture-negative interface abscess which was cured with surgical cleaning and intensive medical treatment. The most common complication encountered was epithelial defects, followed by flap striae. Our study showed that LASIK with a microkeratome has a relatively low incidence of intraoperative and early postoperative flap complications. The authors have no financial interest in any of the issues contained in this article and have no proprietary interest in the development of marketing of or materials used in this study.

  4. [Hereditary sensory and autonomic neuropathy type II A: early neurological and skeletal findings].

    Science.gov (United States)

    Esmer, C; Díaz Zambrano, S; Santos Díaz, M A; González Huerta, L M; Cuevas Covarrubias, S A; Bravo Oro, A

    2014-04-01

    The hereditary sensory and autonomic neuropathies are genetic disorders characterized by the loss of sensation including pain, tactile and temperature. Its clinical and molecular features vary widely; the symptoms may begin from birth or be noticed in the first or second decade, with different types of complications of trauma to the extremities such as ulcers, mutilations and acral amputations. They are classified into six groups from I to VI, determined by the abnormality in eleven genes leading to phenotypic variations in the age of onset and the presence or absence of dysautonomia signs. With the exception of type I, all are autosomal recessive. The type II of these neuropathies is characterized by insensitivity to pain, heat and proprioception. We describe three members of a Mexican family with WNK1 gene mutation that caused hereditary neuropathy IIA.

  5. Early metabolic markers that anticipate loss of insulin independence in type 1 diabetic islet allograft recipients.

    Science.gov (United States)

    Hirsch, D; Odorico, J; Danobeitia, J S; Alejandro, R; Rickels, M R; Hanson, M; Radke, N; Baidal, D; Hullett, D; Naji, A; Ricordi, C; Kaufman, D; Fernandez, L

    2012-05-01

    The objective of this study was to identify predictors of insulin independence and to establish the best clinical tools to follow patients after pancreatic islet transplantation (PIT). Sequential metabolic responses to intravenous (I.V.) glucose (I.V. glucose tolerance test [IVGTT]), arginine and glucose-potentiated arginine (glucose-potentiated arginine-induced insulin secretion [GPAIS]) were obtained from 30 patients. We determined the correlation between transplanted islet mass and islet engraftment and tested the ability of each assay to predict return to exogenous insulin therapy. We found transplanted islet mass within an average of 16 709 islet equivalents per kg body weight (IEQ/kg BW; range between 6602 and 29 614 IEQ/kg BW) to be a poor predictor of insulin independence at 1 year, having a poor correlation between transplanted islet mass and islet engraftment. Acute insulin response to IVGTT (AIR(GLU) ) and GPAIS (AIR(max) ) were the most accurate methods to determine suboptimal islet mass engraftment. AIR(GLU) performed 3 months after transplant also proved to be a robust early metabolic marker to predict return to insulin therapy and its value was positively correlated with duration of insulin independence. In conclusion, AIR(GLU) is an early metabolic assay capable of anticipating loss of insulin independence at 1 year in T1D patients undergoing PIT and constitutes a valuable, simple and reliable method to follow patients after transplant.

  6. Spatiotemporal features of early neuronogenesis differ in wild-type and albino mouse retina

    Science.gov (United States)

    Rachel, Rivka A.; Dolen, Gul; Hayes, Nancy L.; Lu, Alice; Erskine, Lynda; Nowakowski, Richard S.; Mason, Carol A.

    2002-01-01

    In albino mammals, lack of pigment in the retinal pigment epithelium is associated with retinal defects, including poor visual acuity from a photoreceptor deficit in the central retina and poor depth perception from a decrease in ipsilaterally projecting retinal fibers. Possible contributors to these abnormalities are reported delays in neuronogenesis (Ilia and Jeffery, 1996) and retinal maturation (Webster and Rowe, 1991). To further determine possible perturbations in neuronogenesis and/or differentiation, we used cell-specific markers and refined birth dating methods to examine these events during retinal ganglion cell (RGC) genesis in albino and pigmented mice from embryonic day 11 (E11) to E18. Our data indicate that relative to pigmented mice, more ganglion cells are born in the early stages of neuronogenesis in the albino retina, although the initiation of RGC genesis in the albino is unchanged. The cellular organization of the albino retina is perturbed as early as E12. In addition, cell cycle kinetics and output along the nasotemporal axis differ in retinas of albino and pigmented mice, both absolutely, with the temporal aspect of the retina expanded in albino, and relative to the position of the optic nerve head. Finally, blocking melanin synthesis in pigmented eyecups in culture leads to an increase in RGC differentiation, consistent with a role for melanin formation in regulating RGC neuronogenesis. These results point to spatiotemporal defects in neuronal production in the albino retina, which could perturb expression of genes that specify cell fate, number, and/or projection phenotype.

  7. Serum uric acid and its association with hypertension, early nephropathy and chronic kidney disease in type 2 diabetic patients

    Directory of Open Access Journals (Sweden)

    Mohamed Fouad

    Full Text Available Abstract Introduction: Early detection diabetic nephropathy (DN is important. Whether serum uric acid (SUA has a role in the development of DN is not known. Objective: To study the relationship between SUA and hypertension, early nephropathy and progression of chronic kidney disease (CKD in type 2 diabetes mellitus (T2DM. Methods: The total number of the study was 986 participants, according to presence and duration of diabetes were classified into three groups. Group I; including 250 healthy participants. Group II; including 352 with onset of diabetes 5 years. All participants were submitted to complete clinical examination, anthropometric measurements, laboratory investigations, including glycosylated hemoglobin (HbA1C, as well triglycerides to high-density lipoprotein ratios (TG/HDL-C, SUA, urinary albumin/creatinine ratio (ACR and estimated glomerular filtration rate (eGFR. Results: SUA, BP, HbA1c, TG/HDL-C ratio, and ACR levels were significantly higher in group III than group I, II and in II than I. eGFR significantly lower in group III than group I, II and in II than I (p 6.1 mg/dl, > 6.2 mg/dl and > 6.5 mg/dl had a greater sensitivity and specificity for identifying hypertension, early nephropathy and decline eGFR respectively. Conclusion: Even high normal SUA level, was associated with the risk of hypertension, early nephropathy and decline of eGFR. Moreover SUA level may identify the onset of hypertension, early nephropathy and progression of CKD in T2DM.

  8. The Hi content of early-type galaxies from the ALFALFA survey. II. The case of low density environments

    Science.gov (United States)

    Grossi, M.; di Serego Alighieri, S.; Giovanardi, C.; Gavazzi, G.; Giovanelli, R.; Haynes, M. P.; Kent, B. R.; Pellegrini, S.; Stierwalt, S.; Trinchieri, G.

    2009-05-01

    Aims: We present the analysis of the Hi content of a sample of early-type galaxies (ETGs) in low-density environments (LDEs) using the data set provided by the Arecibo Legacy Fast ALFA (ALFALFA) survey. We compare their properties to the sample in the Virgo cluster that we studied in a previous paper (di Serego Alighieri et al. 2007, A&A, 474, 851, Paper I). Our aim is both to investigate how the cool interstellar medium (ISM) of these systems depends on the galaxy mass and the environment and to relate the properties of the neutral hydrogen to the warm phases of the ISM. Methods: We have selected a sample of 62 nearby ETGs (V21-cm measurements reported in the literature. One by one comparison with the available material confirms, as expected, that ALFALFA data are, with rare exceptions, of equal or better quality than the best spectra previously obtained for these objects. All together, our analysis doubles the number of known gas-rich ETGs in this area. The Hi detection rate is 44% in luminous ETGs (MB -17). In both cases it is 10 times higher than that of the Virgo cluster. The presence of gas can be related to a recent star formation activity: 60% of all ETGs with Hi have optical emission line ratios typical of star-forming galaxies and blue colours suggesting the presence of young stellar populations, especially in the dwarf subsample. Conclusions: We show that the Hi detection rate of ETGs depends both on the environment and mass. The fraction of early-type systems with neutral hydrogen is higher in more massive objects when compared to early-type dwarfs. The ETGs in LDEs seem to have more heterogeneous properties than their Virgo cluster counterparts, since they are able to retain a cold interstellar gas component and to support star formation activity even at recent epochs.

  9. AMUSE-VIRGO. III. MID-INFRARED PHOTOMETRY OF EARLY-TYPE GALAXIES AND LIMITS ON OBSCURED NUCLEAR EMISSION

    Energy Technology Data Exchange (ETDEWEB)

    Leipski, Christian [Max-Planck Institut fuer Astronomie (MPIA), Koenigstuhl 17, D-69117 Heidelberg (Germany); Gallo, Elena; Miller, Brendan P. [Department of Astronomy, University of Michigan, 500 Church St., Ann Arbor, MI 48109 (United States); Treu, Tommaso; Antonucci, Robert [Department of Physics, University of California, Santa Barbara, CA 93106 (United States); Woo, Jong-Hak, E-mail: leipski@mpia-hd.mpg.de [Department of Physics and Astronomy, Seoul National University, Seoul, 151-742 (Korea, Republic of)

    2012-01-10

    We complete our census of low-level nuclear activity in Virgo Cluster early-type galaxies by searching for obscured emission using Spitzer Space Telescope mid-infrared (MIR) imaging at 24 {mu}m. Of a total sample of 95 early-type galaxies, 53 objects are detected, including 16 showing kiloparsec-scale dust in optical images. One-dimensional and two-dimensional surface photometry of the 37 detections without extended dust features reveals that the MIR light is more centrally concentrated than the optical light as traced by Hubble Space Telescope F850LP-band images. No such modeling was performed for the sources with dust detected in the optical images. We explore several possible sources of the MIR excess emission, including obscured nuclear emission. We find that radial metallicity gradients in the stellar population appear to be a natural and most likely explanation for the observed behavior in a majority of the sources. Alternatively, if the concentrated MIR emission were due to nuclear activity, it would imply a MIR-to-X luminosity ratio {approx}5-10 for the low-luminosity active galactic nucleus (AGN) detected in X-rays by our survey. This ratio is an order of magnitude larger than that of typical low-luminosity AGNs and would imply an unusual spectral energy distribution. We conclude that the black holes found by our survey in quiescent early-type galaxies in Virgo have low bolometric Eddington ratios arising from low accretion rates and/or highly radiatively inefficient accretion.

  10. The Sloan Lens ACS Survey. I. A Large Spectroscopically Selected Sample of Massive Early-Type Lens Galaxies

    Science.gov (United States)

    Bolton, Adam S.; Burles, Scott; Koopmans, Leon V. E.; Treu, Tommaso; Moustakas, Leonidas A.

    2006-01-01

    The Sloan Lens ACS (SLACS) Survey is an efficient Hubble Space Telescope (HST) Snapshot imaging survey for new galaxy-scale strong gravitational lenses. The targeted lens candidates are selected spectroscopically from the Sloan Digital Sky Survey (SDSS) database of galaxy spectra for having multiple nebular emission lines at a redshift significantly higher than that of the SDSS target galaxy. The SLACS survey is optimized to detect bright early-type lens galaxies with faint lensed sources in order to increase the sample of known gravitational lenses suitable for detailed lensing, photometric, and dynamical modeling. In this paper, the first in a series on the current results of our HST Cycle 13 imaging survey, we present a catalog of 19 newly discovered gravitational lenses, along with nine other observed candidate systems that are either possible lenses, nonlenses, or nondetections. The survey efficiency is thus >=68%. We also present Gemini 8 m and Magellan 6.5 m integral-field spectroscopic data for nine of the SLACS targets, which further support the lensing interpretation. A new method for the effective subtraction of foreground galaxy images to reveal faint background features is presented. We show that the SLACS lens galaxies have colors and ellipticities typical of the spectroscopic parent sample from which they are drawn (SDSS luminous red galaxies and quiescent MAIN sample galaxies), but are somewhat brighter and more centrally concentrated. Several explanations for the latter bias are suggested. The SLACS survey provides the first statistically significant and homogeneously selected sample of bright early-type lens galaxies, furnishing a powerful probe of the structure of early-type galaxies within the half-light radius. The high confirmation rate of lenses in the SLACS survey suggests consideration of spectroscopic lens discovery as an explicit science goal of future spectroscopic galaxy surveys.

  11. Early-Life Events, Including Mode of Delivery and Type of Feeding, Siblings and Gender, Shape the Developing Gut Microbiota.

    Directory of Open Access Journals (Sweden)

    Rocio Martin

    Full Text Available Colonization of the infant gut is believed to be critically important for a healthy growth as it influences gut maturation, metabolic, immune and brain development in early life. Understanding factors that influence this process is important, since an altered colonization has been associated with a higher risk of diseases later in life. Fecal samples were collected from 108 healthy neonates in the first half year of life. The composition and functionality of the microbiota was characterized by measuring 33 different bacterial taxa by qPCR/RT qPCR, and 8 bacterial metabolites. Information regarding gender, place and mode of birth, presence of siblings or pets; feeding pattern and antibiotic use was collected by using questionnaires. Regression analysis techniques were used to study associations between microbiota parameters and confounding factors over time. Bacterial DNA was detected in most meconium samples, suggesting bacterial exposure occurs in utero. After birth, colonization by species of Bifidobacterium, Lactobacillus and Bacteroides was influenced by mode of delivery, type of feeding and presence of siblings, with differences found at species level and over time. Interestingly, infant-type bifidobacterial species such as B. breve or B. longum subsp infantis were confirmed as early colonizers apparently independent of the factors studied here, while B. animalis subsp. lactis presence was found to be dependent solely on the type of feeding, indicating that it might not be a common infant gut inhabitant. One interesting and rather unexpected confounding factor was gender. This study contributes to our understanding of the composition of the microbiota in early life and the succession process and the evolution of the microbial community as a function of time and events occurring during the first 6 months of life. Our results provide new insights that could be taken into consideration when selecting nutritional supplementation strategies to

  12. 基于非线性回归模型公立医院产权制度演化对医疗服务产出影响研究%Analysis on the Effects of Public Hospital Poverty System Evolution on the Medical Service Output Based on Non-liner Regression Model

    Institute of Scientific and Technical Information of China (English)

    李习平

    2014-01-01

    Objective: To discuss the effects of public hospitals’ marketization poverty reform and nationalization poverty reform on medical service output in public hospitals, trying to provide experimental references for public hospital reform in China. Methods:Based on the non-liner regression expand model, calculation analysis method and Eviews 7.0 Software were used to introduce nationalization degree and marketization degree into proving the effects of public hospital equity system evolution on the medical service output. Results:Based on the analysis of single factor, it is known that:the government’s input limit on public hospitals increased by 1%, while the medical service output in public hospitals increased by 2.97%. The rate of individual payment in total medical cost increased by 1%, while the medical service output in public hospitals decreased by 2.08%, the rate of individual expenditure in total medical cost increased by 1% while the output of public hospitals decreased by 2.21%. Conclusion: There is a positive correlation between nationalization and output in public hospitals, while the marketization rate has negative correlation with the output. The current public hospital poverty system has limited the contribution of health technical staffs on the medical output in public hospitals, which leads to the multiple practices of medical technical staffs. Because of the undefined poverty demarcation, the hospital managers could not put the centralized limited government resources into the medical service field with pure public product value. The over operation in medical service field with competitive private product value leads to the private product value showed in the proportion in medical service, which results in “expensive and difficult to visit the doctor”.%目的:探讨公立医院市场化产权改革与国有化产权改革对公立医院医疗服务产出的影响,试图为我国公立医院改革提供经验佐证;方法:基于非线

  13. Mucopolysaccharidosis type I (MPS I): Assessment of disease severity, therapeutic options and early diagnosis

    NARCIS (Netherlands)

    de Ru, M.H.

    2013-01-01

    Bepaalde stoffen in bloed en urine, zogeheten biomarkers, kunnen gebruikt worden voor het stellen van de diagnose van de stofwisselingsziekte Mucopolysaccharidose type I (MPS I) op basis van bloed afgenomen bij de hielprikscreening. Dit blijkt uit het onderzoek van Minke de Ru dat zich richtte op he

  14. Preventing Early Leaving in VET: Distributed Pedagogical Leadership in Characterising Five Types of Successful Organisations

    Science.gov (United States)

    Jappinen, Aini-Kristiina

    2010-01-01

    This paper presents 14 organisers of upper secondary education in Finland with exceptionally low dropout rates. As a case study in which common strengths were defined, five types of organisations with typical characteristics were found: "Working life-oriented," "Networked and team-based," "Cosy and traditional," "Guidance-oriented," and…

  15. A rare early-type star revealed in the Wing of the Small Magellanic Cloud

    CERN Document Server

    Evans, C J; Oskinova, L M; Gallagher, J S; Chu, Y -H; Gruendl, R A; Hamann, W -R; Hénault-Brunet, V; Todt, H

    2012-01-01

    Sk 183 is the visually-brightest star in the N90 nebula, a young star-forming region in the Wing of the Small Magellanic Cloud (SMC). We present new optical spectroscopy from the Very Large Telescope which reveals Sk 183 to be one of the most massive O-type stars in the SMC. Classified as an O3-type dwarf on the basis of its nitrogen spectrum, the star also displays broadened He I absorption which suggests a later type. We propose that Sk 183 has a composite spectrum and that it is similar to another star in the SMC, MPG 324. This brings the number of rare O2- and O3-type stars known in the whole of the SMC to a mere three. We estimate physical parameters for Sk 183 from analysis of its spectrum. For a single-star model, we estimate an effective temperature of 46+/-2 kK, a low mass-loss rate of ~10^-7 Msun yr^-1, and a spectroscopic mass of 46^+9_-8 Msun (for an adopted distance modulus of 18.7 mag to the young population in the SMC Wing). An illustrative binary model requires a slightly hotter temperature (~...

  16. Exposure to sunshine early in life prevented development of type 1 diabetes in Danish boys

    DEFF Research Database (Denmark)

    Jacobsen, Ramune; Frederiksen, Peder; Heitmann, Berit L

    2015-01-01

    BACKGROUND: We aimed to assess the association between exposure to sunshine during gestation and the risk of type 1 diabetes (T1D) in Danish children. METHODS: The study population included 331,623 individuals born in Denmark from 1983 to 1988; 886 (0.26%) developed T1D by the age of 15 years. Th...

  17. On early starters and late bloomers: the development of sexual behavior in adolescence across personality types

    NARCIS (Netherlands)

    Baams, L.; Overbeek, G.; Dubas, J.S.; van Aken, M.A.G.

    2014-01-01

    Little is known about the relationship between personality and sexual development among mid-adolescents. In the current study, we used a person-centered approach to investigate the relation between personality types and the development of sexual behavior. We hypothesized that undercontrolling adoles

  18. On early starters and late bloomers : The development of sexual behavior in adolescence across personality types

    NARCIS (Netherlands)

    Baams, Laura; Overbeek, Geertjan; Dubas, Judith Semon; Van Aken, Marcel A G

    2014-01-01

    Little is known about the relationship between personality and sexual development among mid-adolescents. In the current study, we used a person-centered approach to investigate the relation between personality types and the development of sexual behavior. We hypothesized that undercontrolling adoles

  19. Early life origins of insulin resistance and type 2 diabetes in India and other Asian countries.

    Science.gov (United States)

    Yajnik, C S

    2004-01-01

    There is a rapidly increasing epidemic of type 2 diabetes in India and other Asian countries. The thrifty genotype and the thrifty phenotype are two nonexclusive explanations. People in the Indian subcontinent have faced undernutrition for many generations, and Indian babies are among the smallest in the world. However, the diabetes epidemic is of recent origin, and diabetes is more common among urban than rural Indians despite the higher birth weight of urban babies. This suggests that postnatal factors must also contribute. Thus, a life-course model of evolution of insulin resistance and type 2 diabetes, incorporating fetal, postnatal and adult components, seems most appropriate. For a given BMI, Indians have a higher percentage of body fat and more visceral fat than members of other populations. This thin-fat phenotype is present at birth. Neonatal size and body composition are influenced by parental size, maternal food intake, physical activity and circulating concentrations of nutrients and metabolites (folate, glucose, triglycerides, cholesterol etc.). Maternal insulin resistance promotes transfer of nutrients to the fetus. Accelerated childhood growth is another risk factor for adiposity and insulin resistance, especially in children born small. Childhood growth seems to be more influenced by paternal genetic factors, whereas intrauterine growth is more influenced by maternal factors (intrauterine environment). Urban lifestyles, including poor diet and sedentary habits, promote further obesity, insulin resistance and type 2 diabetes. These factors may be amenable to correction. Prevention of type 2 diabetes must begin in utero and continue throughout the life course.

  20. Retinal Vascular Fractals Correlate With Early Neurodegeneration in Patients With Type 2 Diabetes Mellitus

    DEFF Research Database (Denmark)

    Frydkjaer-Olsen, Ulrik; Soegaard Hansen, Rasmus; Pedersen, Knud

    2015-01-01

    Purpose: To investigate the correlation between the retinal vascular fractal dimension (Fd) and neurodegenerative changes in patients with no or mild diabetic retinopathy (DR). Methods: In this cross-sectional study we examined 103 patients with type 2 diabetes mellitus (T2DM) with no or mild DR....

  1. Early infant feeding and risk of developing islet autoimmunity and type 1 diabetes.

    Science.gov (United States)

    Chmiel, Ruth; Beyerlein, Andreas; Knopff, Annette; Hummel, Sandra; Ziegler, Anette-G; Winkler, Christiane

    2015-06-01

    We investigated whether food supplementation within the first year life or age at introduction of gluten-containing foods influenced the risk of developing islet autoimmunity and type 1 diabetes. A total of 2,291 children with a family history of type 1 diabetes were prospectively followed from birth for 28,983 patient years (median 13.1 years). Dietary exposure data were collected by questionnaires, food records and by family interview. Exposure to gluten-containing foods before age 3 months, which occurred in 19 children, increased the risk of developing islet autoantibodies (n = 4), multiple islet autoantibodies (n = 4), and type 1 diabetes (n = 3) compared to exclusive breastfeeding within the first 3 months [adjusted hazard ratio (HR) 3.97 (95 % confidence interval 1.41-11.17), 5.39 (1.89-15.35), and 3.45 (1.04-11.48), respectively] and also compared to first exposure to gluten between 3.1 and 6.0 months of age [adjusted HR 3.40 (1.19-9.70), 4.25 (1.47-12.26), and 3.43 (1.01-11.66), respectively]. Children who received infant formula or other solid food within the first 3 months and children who received gluten-containing foods after age 6 months did not have an increased risk of islet autoantibodies, multiple islet autoantibodies or type 1 diabetes. Our present data affirm that compliance to infant feeding guidelines is a possible way to reduce type 1 diabetes risk in genetically susceptible children.

  2. Size growth of red-sequence early-type galaxies in clusters in the last 10 Gyr

    Science.gov (United States)

    Andreon, S.; Dong, Hui; Raichoor, A.

    2016-08-01

    We carried out a photometric and structural analysis in the rest-frame V band of a mass-selected (log M/M⊙> 10.7) sample of red-sequence galaxies in 14 galaxy clusters, 6 of which are at z> 1.45, namely JKCS041, IDCS J1426.5+3508, SpARCS104922.6+564032.5, SpARCSJ021524-034331, XDCPJ0044.0-2033, and SPT-CLJ2040-4451. To this end, we reduced/analyzed about 300 orbits of multicolor images taken with the Advanced Camera for Survey and the Wide Field Camera 3 on the Hubble Space Telescope. We uniformly morphologically classified galaxies from z = 0.023 to z = 1.803, and we homogeneously derived sizes (effective radii) for the entire sample. Furthermore, our size derivation allows, and therefore is not biased by, the presence of the usual variety of morphological structures seen in early-type galaxies, such as bulges, bars, disks, isophote twists, and ellipiticy gradients. By using such a mass-selected sample, composed of 244 red-sequence early-type galaxies, we find that the log of the galaxy size at a fixed stellar mass, log M/M⊙ = 11, has increased with time at a rate of 0.023 ± 0.002 dex per Gyr over the last 10 Gyr, in marked contrast with the threefold increase found in the literature for galaxies in the general field over the same period. This suggests, at face value, that secular processes should be excluded as the primary drivers of size evolution because we observed an environmental dependent size growth. Using spectroscopic ages of Coma early-type galaxies we also find that recently quenched early-type galaxies are a numerically minor population not different enough in size to alter the mean size at a given mass, which implies that the progenitor bias is minor, i.e., that the size evolution measured by selecting galaxies at the redshift of observation is indistinguishable from the one that compares ancestors and descendents. Full Table 3 is only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc

  3. Tracing the evolution of nearby early-type galaxies in low density environments. The Ultraviolet view from GALEX

    CERN Document Server

    Rampazzo, R; Marino, A; Bianchi, L; Bressan, A; Buson, L M; Clemens, M; Panuzzo, P; Zeilinger, W W; 10.1007/s10509-010-0586-5

    2011-01-01

    We detected recent star formation in nearby early-type galaxies located in low density environments, with GALEX Ultraviolet (UV) imaging. Signatures of star formation may be present in the nucleus and in outer rings/arm like structures. Our study suggests that such star formation may be induced by different triggering mechanisms, such as the inner secular evolution driven by bars, and minor accretion phenomena. We investigate the nature of the (FUV-NUV) color vs. Mg2 correlation, and suggest that it relates to "downsizing" in galaxy formation.

  4. New insights into the structure of early-type galaxies: the Photometric Plane at z~0.3

    OpenAIRE

    La Barbera, F; Covone, G.; Busarello, G.; Capaccioli, M; Haines, C. P.; Mercurio, A.; Merluzzi, P.

    2005-01-01

    We study the Photometric Plane (PHP), namely the relation between the effective radius re, the mean surface brightness within that radius e, and the Sersic index n, in optical (R and I) and near-infrared (K) bands for a large sample of early-type galaxies (ETGs) in the rich cluster MS1008-1224 at z=0.306. The PHP relation has an intrinsic dispersion of ~32% in re, and turns out to be independent of waveband. This result is consistent with the fact that internal colour gradients of ETGs can ha...

  5. Postoperative early hemolytic anemia due to inverted teflon felt strip after emergency repair for type A dissection.

    Science.gov (United States)

    Hata, M; Yoshitake, I; Wakui, S; Unosawa, S; Hata, H; Shiono, M

    2012-10-01

    A 39-year-old man underwent emergency surgery for type A acute aortic dissection complicated by paraplegia. However, hemolytic anemia increased significantly due to severe stenosis of the proximal anastomosis one month after surgery. He finally underwent a redo procedure 4 months after the initial operation whereupon it was verified that half of the inner felt strip used for proximal stump fixation had turned up and was protruding into the inner lumen. We report here on a rare case of survival of postoperative early hemolytic anemia due to severe graft stenosis caused by an inverted inner Teflon felt strip without any extra vascular compression.

  6. Kinematics and stellar populations of low-luminosity early-type galaxies in the Abell 496 cluster

    Science.gov (United States)

    Chilingarian, I. V.; Cayatte, V.; Durret, F.; Adami, C.; Balkowski, C.; Chemin, L.; Laganá, T. F.; Prugniel, P.

    2008-07-01

    Context: The morphology and stellar populations of low-luminosity early-type galaxies in clusters have until now been limited to a few relatively nearby clusters such as Virgo or Fornax. Scenarii for the formation and evolution of dwarf galaxies in clusters are therefore not well constrained. Aims: We investigate here the morphology and stellar populations of low-luminosity galaxies in the relaxed richness class 1 cluster Abell 496 (z = 0.0330). Methods: Deep multiband imaging obtained with the CFHT Megacam allowed us to select a sample of faint galaxies, defined here as objects with magnitudes 18 power R = 6300. We present structural analysis and colour maps for the 48 galaxies belonging to the cluster. We fit the spectra of 46 objects with PEGASE.HR synthetic spectra to estimate the ages, metallicities, and velocity dispersions. We estimated possible biases by similarly analysing spectra of ~1200 early-type galaxies from the Sloan Digital Sky Survey Data Release 6 (SDSS DR6). We computed values of α/Fe abundance ratios from the measurements of Lick indices. We briefly discuss effects of the fixed aperture size on the measurements. Results: For the first time, high-precision estimates of stellar population properties have been obtained for a large sample of faint galaxies in a cluster, allowing for the extension of relations between stellar populations and internal kinematics to the low-velocity dispersion regime. We have revealed a peculiar population of elliptical galaxies in the core of the cluster, resembling massive early-type galaxies by their stellar population properties and velocity dispersions, but having luminosities of about 2 mag fainter. Conclusions: External mechanisms of gas removal (ram pressure stripping and gravitational harassment) are more likely to have occurred than internal mechanisms such as supernova-driven winds. The violent tidal stripping of intermediate-luminosity, early-type galaxies in the cluster core can explain the properties of

  7. Early definition of type, degree and audiogram shape in childhood hearing impairment.

    Science.gov (United States)

    Conti, G; Gallus, R; Fetoni, A R; Martina, B M; Muzzi, E; Orzan, E; Bastanza, G

    2016-02-01

    In the context of permanent childhood hearing loss, early audiological diagnosis is a prerequisite for activation of an adequate rehabilitation program to prevent or limit the known effects that auditory deprivation determines on language development and cognitive skills in neonates. Audiological diagnosis consists schematically of three phases: identification of subjects at risk, definition of hearing loss and/or children features, verification of appropriateness of diagnosis itself and a rehabilitation programme. Strategies and methods of audiological diagnosis are well defined and include an integration of data coming from objective methods with clinical and behavioural data. Although the substantial effectiveness of procedures and a general consensus on their use and interpretation have been defined, there are several critical issues concerning the achievement of this objective, which will be discussed in this paper. © Copyright by Società Italiana di Otorinolaringologia e Chirurgia Cervico-Facciale.

  8. Patterns and predictors of paternal involvement in early adolescents' type 1 diabetes management over 3 years.

    Science.gov (United States)

    Hilliard, Marisa E; Rohan, Jennifer M; Rausch, Joseph R; Delamater, Alan; Pendley, Jennifer Shroff; Drotar, Dennis

    2014-01-01

    To document trajectories of paternal involvement in diabetes management and examine bidirectional associations with diabetes outcomes across early adolescence. 3-year prospective assessment of paternal involvement, diabetes self-management, and glycemic control among 136 youth (age 9-12 at baseline) and their mothers and fathers. Unconditional growth curves demonstrated decreasing amount (maternal report: F(1,128) = 14.79; paternal report: F(1,111) = 12.95, ps Controlling for covariates, lower youth self-management predicted an increasing slope in fathers' self-reported amount of involvement (b = -0.15 to -0.22, p management (b = -0.01, p management. Communication about ways to enhance fathers' involvement before this transition may help prevent or reduce declining diabetes management and control common in adolescence.

  9. Early Rehabilitation of Incisors with Dentinogenesis Imperfecta Type II - Case Report.

    Science.gov (United States)

    Beltrame, Ana Paula Ca; Rosa, Maíra Mery; Noschang, Ricardo At; Almeida, Izabel Cs

    Dentinogenesis imperfecta is an phenotypic alteration in the formation of the organic matrix. It causes the rapid and progressive wear of tooth structure, which may compromise tooth function and aesthetics. This is a case of a 1y, 8m-old child with dentinogenesis imperfecta. All teeth presented with an opalescent appearance and grayish color hue. Compromised structural integrity was noted as excessive wear and fracturing of the enamel from the dentin layer. With low doses of midazolam (oral) and chloral hydrate (rectal) administration, in a hospital environment, sedation was used to aid full mouth rehabilitation. Direct bonded restorations were performed on primary maxillary incisors and indirect restorations, pre-made on a plaster model using composite resin, were performed on primary mandibular incisors. After 32 months, we observed that diagnosis and early treatment allowed preventive maintenance of the patient's primary dentition, maintaining tooth function and esthetics.

  10. The effects of mulch types on earliness, fruit set ratios, and yield for apricot

    Directory of Open Access Journals (Sweden)

    Burcu YAMAN

    2013-12-01

    Full Text Available The objective of this study is to enhance earliness and fruit set, which is a crucial factor in apricot production. The study was conducted on an apricot orchard located in Serinyol town of Antakya between 2010 and 2011. In the experiment, ‘Ninfa’, ‘Bebeco’, ‘Aurora’ and ‘Roksana’ cultivars were used. The experimental cultivars were planted on 3 x 6 m in 2006 as one-year-old plants budded on seedling rootstocks. The plants have been irrigated by drip irrigation since their transplantation. In the experiment, there were four treatments as follows: control, transparent polyethylene mulch, organic mulch, and transparent polyethylene mulch + organic mulch. As plastic mulch, a 0.02 mm (UV+AB transparent plastic 1.60 cm in width; and, wheat straw as organic mulch was used. The experiment was designed as split-plot experimental design with 5 replications having 1 tree in each replication. The mulch was applied based on the physiological stages of the trees; prior to break of dormancy and opening of the buds. In the study, phenological observations (first flowering, full flowering and the end of the flowering as well as fruit set ratios, the status of vegetative development and yield were determined. As a result, in the both years, the flowering and fruit set ratios of control trees were found lower than the organic mulch or plastic mulch treated trees. Mulching treatments were enhanced 2-4 days earliness compared to control treatment for fruit maturity; and transparent polyethylene mulch + organic mulch was found partially better than the others two mulching treatments.

  11. Proton and Fe Ion-Induced Early and Late Chromosome Aberrations in Different Cell Types

    Science.gov (United States)

    Lu, Tao; Zhang, Ye; Yeshitla, Samrawit; Bowler, Deborah; Kadhim, Munira; Wilson, Bobby; Wu, Honglu

    2016-01-01

    Genomic instability, induced by various metabolic, genetic, and environmental factors, is the driving force of tumorigenesis. Radiation exposure from different types of radiation sources induces different types of DNA damages, increases mutation and chromosome aberration rates, and increases cellular transformation in vitro and in vivo experiments. The cell survival rates and frequency of chromosome aberrations depend on the genetic background and radiation sources. To further understand genomic instability induced by charged particles, we exposed human lymphocytes ex vivo, human fibroblast cells, human mammary epithelial cells, and bone marrow cells isolated from CBA/CaH and C57BL/6 mice to high energy protons and Fe ions, and collected chromosomes at different generations after exposure. Chromosome aberrations were analyzed with fluorescent in situ hybridization with whole chromosome specific probes.

  12. Early spontaneous regression of a hypothalamic/chiasmatic mass in neurofibromatosis type 1: MR findings

    Energy Technology Data Exchange (ETDEWEB)

    Zuccoli, G.; Ferrozzi, F.; Bassi, P. [Department of Radiology, University of Parma, V. Gramsci, 14, I-43100 Parma (Italy); Sigorini, M.; Virdis, R. [Department of Paediatrics, University of Parma, V. Gramsci, 14, I-43100 Parma (Italy); Bellomi, M. [Division of Radiology, European Institute of Oncology, Milan (Italy)

    2000-07-01

    A patient with neurofibromatosis type 1 was found to have an enhancing mass in the hypothalamus and in the anterior optic pathway. A 3-month MR study showed a reduction in the size and enhancement of the mass. At a 9-month MR follow-up the mass disappeared and ceased to enhance. This report shows the unusual behaviour of a hypothalamic/chiasmatic mass confirming that in such asymptomatic cases the conservative management can be considered the treatment of choice. (orig.)

  13. Genetic analysis of Tunisian families with Usher syndrome type 1: toward improving early molecular diagnosis

    OpenAIRE

    2016-01-01

    Purpose Usher syndrome accounts for about 50% of all hereditary deaf-blindness cases. The most severe form of this syndrome, Usher syndrome type I (USH1), is characterized by profound congenital sensorineural deafness, vestibular dysfunction, and retinitis pigmentosa. Six USH1 genes have been identified, MYO7A, CDH23, PCDH15, USH1C, SANS, and CIB2, encoding myosin VIIA, cadherin-23, protocadherin-15, harmonin, scaffold protein containing ankyrin repeats and a sterile alpha motif (SAM) domain,...

  14. Zebrafish Plzf transcription factors enhance early type I IFN response induced by two non-enveloped RNA viruses.

    Science.gov (United States)

    Aleksejeva, E; Houel, A; Briolat, V; Levraud, J-P; Langevin, C; Boudinot, P

    2016-04-01

    The BTB-POZ transcription factor Promyelocytic Leukemia Zinc Finger (PLZF, or ZBTB16) has been recently identified as a major factor regulating the induction of a subset of Interferon stimulated genes in human and mouse. We show that the two co-orthologues of PLZF found in zebrafish show distinct expression patterns, especially in larvae. Although zbtb16a/plzfa and zbtb16b/plzfb are not modulated by IFN produced during viral infection, their over-expression increases the level of the early type I IFN response, at a critical phase in the race between the virus and the host response. The effect of Plzfb on IFN induction was also detectable after cell infection by different non-enveloped RNA viruses, but not after infection by the rhabdovirus SVCV. Our findings indicate that plzf implication in the regulation of type I IFN responses is conserved across vertebrates, but at multiple levels of the pathway and through different mechanisms.

  15. A new brittle star from the early Carboniferous of Poland and its implications on Paleozoic modern-type ophiuroid systematics

    Directory of Open Access Journals (Sweden)

    Ben Thuy

    2015-12-01

    Full Text Available The fossil record of Paleozoic ophiuroids includes a number of forms which share striking similarities with modern relatives in terms of skeletal morphology. These so called modern-type Paleozoic ophiuroids yield an enormous potential for a better understanding of ophiuroid evolution, yet the scarcity of accurate and sufficiently detailed morphological descriptions available to date precludes any further-reaching assessments. Here, we describe an articulated ophiuroid specimen from the Late Tournaisian (early Carboniferous of Czatkowice quarry, southern Poland, as a new species Aganaster jagiellonicus sp. nov. The good preservation of the specimen allowed for a morphological analysis at a level comparable to recent ophiuroid descriptions. It shows remarkable morphological similarities with extant former ophiolepidids Ophiomusium and Ophiosphalma. The new find thus contributes to a solid basis for future investigations on the position of the modern-type Paleozoic ophiuroid in the phylogeny of the class.

  16. Dependence of Early and Late Chromosomal Aberrations on Radiation Quality and Cell Types

    Science.gov (United States)

    Lu, Tao; Zhang, Ye; Krieger, Stephanie; Yeshitla, Samrawit; Goss, Rosalin; Bowler, Deborah; Kadhim, Munira; Wilson, Bobby; Rohde, Larry; Wu, Honglu

    2017-01-01

    Exposure to radiation induces different types of DNA damage, increases mutation and chromosome aberration rates, and increases cellular transformation in vitro and in vivo. The susceptibility of cells to radiation depends on genetic background and growth condition of cells, as well as types of radiation. Mammalian cells of different tissue types and with different genetic background are known to have different survival rate and different mutation rate after cytogenetic insults. Genomic instability, induced by various genetic, metabolic, and environmental factors including radiation, is the driving force of tumorigenesis. Accurate measurements of the relative biological effectiveness (RBE) is important for estimating radiation-related risks. To further understand genomic instability induced by charged particles and their RBE, we exposed human lymphocytes ex vivo, human fibroblast AG1522, human mammary epithelial cells (CH184B5F5/M10), and bone marrow cells isolated from CBA/CaH(CBA) and C57BL/6 (C57) mice to high energy protons and Fe ions. Normal human fibroblasts AG1522 have apparently normal DNA damage response and repair mechanisms, while mammary epithelial cells (M10) are deficient in the repair of DNA DSBs. Mouse strain CBA is radio-sensitive while C57 is radio-resistant. Metaphase chromosomes at different cell divisions after radiation exposure were collected and chromosome aberrations were analyzed as RBE for different cell lines exposed to different radiations at various time points up to one month post irradiation.

  17. Early nutrition and risk of Type 1 diabetes mellitus--a nationwide case-control study in preschool children.

    Science.gov (United States)

    Rosenbauer, J; Herzig, P; Kaiser, P; Giani, G

    2007-09-01

    The evidence on the role of environmental factors in the development of type 1 diabetes is conflicting. Reducing potential bias and the variety of exposures we investigated the association between type 1 diabetes risk and nutritional and other environmental exposures in preschool children. This nationwide case-control study included 760 cases newly diagnosed with type 1 diabetes under five years of age during 1992-1995. 630 controls of the same age were selected from the case families' acquaintance. Information on infant diet, foetal, perinatal and socio-economic factors, and family history of diabetes was obtained by a parent-administered questionnaire. Data were analysed by multiple unconditional logistic regression. Duration of breastfeeding and age at introduction of bottle-feeding were inversely associated with type 1 diabetes risk according to a dose-response relationship (trend test pbreastfeeding period and an early introduction of formula feeding (vs. > or =5 months) were 1.31 (1.01-1.69) and 1.34 (1.03-1.74), respectively. Familial type 1 diabetes was found more frequently among diabetic than among control children. Higher social status, late introduction of solid food (> or =5 month), and higher current cow's milk consumption (> or =200 ml/d) were associated with a reduced diabetes risk. A considerable proportion of the diabetic risk among preschool children was explained by modifiable exposures. Our findings indicate that infant feeding is causally associated with type 1 diabetes risk and that a considerable part of new type 1 diabetic cases is potentially preventable.

  18. The mating-type chromosome in the filamentous ascomycete Neurospora tetrasperma represents a model for early evolution of sex chromosomes.

    Directory of Open Access Journals (Sweden)

    Audrius Menkis

    2008-03-01

    Full Text Available We combined gene divergence data, classical genetics, and phylogenetics to study the evolution of the mating-type chromosome in the filamentous ascomycete Neurospora tetrasperma. In this species, a large non-recombining region of the mating-type chromosome is associated with a unique fungal life cycle where self-fertility is enforced by maintenance of a constant state of heterokaryosis. Sequence divergence between alleles of 35 genes from the two single mating-type component strains (i.e. the homokaryotic mat A or mat a-strains, derived from one N. tetrasperma heterokaryon (mat A+mat a, was analyzed. By this approach we were able to identify the boundaries and size of the non-recombining region, and reveal insight into the history of recombination cessation. The non-recombining region covers almost 7 Mbp, over 75% of the chromosome, and we hypothesize that the evolution of the mating-type chromosome in this lineage involved two successive events. The first event was contemporaneous with the split of N. tetrasperma from a common ancestor with its outcrossing relative N. crassa and suppressed recombination over at least 6.6 Mbp, and the second was confined to a smaller region in which recombination ceased more recently. In spite of the early origin of the first "evolutionary stratum", genealogies of five genes from strains belonging to an additional N. tetrasperma lineage indicate independent initiations of suppressed recombination in different phylogenetic lineages. This study highlights the shared features between the sex chromosomes found in the animal and plant kingdoms and the fungal mating-type chromosome, despite fungi having no separate sexes. As is often found in sex chromosomes of plants and animals, recombination suppression of the mating-type chromosome of N. tetrasperma involved more than one evolutionary event, covers the majority of the mating-type chromosome and is flanked by distal regions with obligate crossovers.

  19. Characteristic patterns of dendritic remodeling in early-stage glaucoma: evidence from genetically identified retinal ganglion cell types.

    Science.gov (United States)

    El-Danaf, Rana N; Huberman, Andrew D

    2015-02-11

    Retinal ganglion cell (RGC) loss is a hallmark of glaucoma and the second leading cause of blindness worldwide. The type and timing of cellular changes leading to RGC loss in glaucoma remain incompletely understood, including whether specific RGC subtypes are preferentially impacted at early stages of this disease. Here we applied the microbead occlusion model of glaucoma to different transgenic mouse lines, each expressing green fluorescent protein in 1-2 specific RGC subtypes. Targeted filling, reconstruction, and subsequent comparison of the genetically identified RGCs in control and bead-injected eyes revealed that some subtypes undergo significant dendritic rearrangements as early as 7 d following induction of elevated intraocular pressure (IOP). By comparing specific On-type, On-Off-type and Off-type RGCs, we found that RGCs that target the majority of their dendritic arbors to the scleral half or "Off" sublamina of the inner plexiform layer (IPL) undergo the greatest changes, whereas RGCs with the majority of their dendrites in the On sublamina did not alter their structure at this time point. Moreover, M1 intrinsically photosensitive RGCs, which functionally are On RGCs but structurally stratify their dendrites in the Off sublamina of the IPL, also underwent significant changes in dendritic structure 1 week after elevated IOP. Thus, our findings reveal that certain RGC subtypes manifest significant changes in dendritic structure after very brief exposure to elevated IOP. The observation that RGCs stratifying most of their dendrites in the Off sublamina are first to alter their structure may inform the development of new strategies to detect, monitor, and treat glaucoma in humans.

  20. Effects of Shiga Toxin Type 2 on Maternal and Fetal Status in Rats in the Early Stage of Pregnancy

    Science.gov (United States)

    Sacerdoti, Flavia; Amaral, María M.; Zotta, Elsa; Franchi, Ana M.; Ibarra, Cristina

    2014-01-01

    Shiga toxin type 2 (Stx2), a toxin secreted by Shiga toxin-producing Escherichia coli (STEC), could be one of the causes of maternal and fetal morbimortality not yet investigated. In this study, we examined the effects of Stx2 in rats in the early stage of pregnancy. Sprague-Dawley pregnant rats were intraperitoneally (i.p.) injected with sublethal doses of Stx2, 0.25 and 0.5 ng Stx2/g of body weight (bwt), at day 8 of gestation (early postimplantation period of gestation). Maternal weight loss and food and water intake were analyzed after Stx2 injection. Another group of rats were euthanized and uteri were collected at different times to evaluate fetal status. Immunolocalization of Stx2 in uterus and maternal kidneys was analyzed by immunohistochemistry. The presence of Stx2 receptor (globotriaosylceramide, Gb3) in the uteroplacental unit was observed by thin layer chromatography (TLC). Sublethal doses of Stx2 in rats caused maternal weight loss and pregnancy loss. Stx2 and Gb3 receptor were localized in decidual tissues. Stx2 was also immunolocalized in renal tissues. Our results demonstrate that Stx2 leads to pregnancy loss and maternal morbidity in rats in the early stage of pregnancy. This study highlights the possibility of human pregnancy loss and maternal morbidity mediated by Stx2. PMID:25157355

  1. Effects of Shiga Toxin Type 2 on Maternal and Fetal Status in Rats in the Early Stage of Pregnancy

    Directory of Open Access Journals (Sweden)

    Flavia Sacerdoti

    2014-01-01

    Full Text Available Shiga toxin type 2 (Stx2, a toxin secreted by Shiga toxin-producing Escherichia coli (STEC, could be one of the causes of maternal and fetal morbimortality not yet investigated. In this study, we examined the effects of Stx2 in rats in the early stage of pregnancy. Sprague-Dawley pregnant rats were intraperitoneally (i.p. injected with sublethal doses of Stx2, 0.25 and 0.5 ng Stx2/g of body weight (bwt, at day 8 of gestation (early postimplantation period of gestation. Maternal weight loss and food and water intake were analyzed after Stx2 injection. Another group of rats were euthanized and uteri were collected at different times to evaluate fetal status. Immunolocalization of Stx2 in uterus and maternal kidneys was analyzed by immunohistochemistry. The presence of Stx2 receptor (globotriaosylceramide, Gb3 in the uteroplacental unit was observed by thin layer chromatography (TLC. Sublethal doses of Stx2 in rats caused maternal weight loss and pregnancy loss. Stx2 and Gb3 receptor were localized in decidual tissues. Stx2 was also immunolocalized in renal tissues. Our results demonstrate that Stx2 leads to pregnancy loss and maternal morbidity in rats in the early stage of pregnancy. This study highlights the possibility of human pregnancy loss and maternal morbidity mediated by Stx2.

  2. [Guillain-Barré syndrome in a course of early cutaneous type of Lyme borreliosis: diagnostic and therapeutic difficulties].

    Science.gov (United States)

    Wiszniewska, Małgorzata; Szmaglińska, Hanna; Kozubski, Wojciech

    2005-01-01

    A case is reported of a 33-year-old man in whom Guillain-Barré syndrome (GBs) developed three weeks after a tick's sting. At the sting site typical for an early cutaneous type of Lyme borreliosis -- erythema migrans -- appeared. The demyelinating polyradiculoneuropathy of GBs occurred after disappearance of erythema migrans, and was manifested by progressive neuropathic symmetrical limb weakness with distal numbness and pain, and bilateral facial paralysis. The GBs was confirmed by electrophysiological examination and elevated protein concentration with a normal range of cells in the cerebrospinal fluid. Antibodies IgM and IgG against Borrelia burgdorferi in the blood serum and cerebrospinal fluid assessed using immunoenzymatic assay, MEIA, were negative on account of their early search. The above findings suggested that the GBs appearance after the probable Borrelia burgdorferi infection was in fact due to that infection. The patient recovered after treatment with plasma-phoresis and corticosteroid therapy followed by intravenous immunoglobulin, and physiotherapy. This is the first case in the Polish neurological literature of GBs with an early skin form of borreliosis which developed after the tick's sting.

  3. The Sinorhizobium (Ensifer) fredii HH103 Type 3 Secretion System Suppresses Early Defense Responses to Effectively Nodulate Soybean.

    Science.gov (United States)

    Jiménez-Guerrero, Irene; Pérez-Montaño, Francisco; Monreal, José Antonio; Preston, Gail M; Fones, Helen; Vioque, Blanca; Ollero, Francisco Javier; López-Baena, Francisco Javier

    2015-07-01

    Plants that interact with pathogenic bacteria in their natural environments have developed barriers to block or contain the infection. Phytopathogenic bacteria have evolved mechanisms to subvert these defenses and promote infection. Thus, the type 3 secretion system (T3SS) delivers bacterial effectors directly into the plant cells to alter host signaling and suppress defenses, providing an appropriate environment for bacterial multiplication. Some rhizobial strains possess a symbiotic T3SS that seems to be involved in the suppression of host defenses to promote nodulation and determine the host range. In this work, we show that the inactivation of the Sinorhizobium (Ensifer) fredii HH103 T3SS negatively affects soybean nodulation in the early stages of the symbiotic process, which is associated with a reduction of the expression of early nodulation genes. This symbiotic phenotype could be the consequence of the bacterial triggering of soybean defense responses associated with the production of salicylic acid (SA) and the impairment of the T3SS mutant to suppress these responses. Interestingly, the early induction of the transcription of GmMPK4, which negatively regulates SA accumulation and defense responses in soybean via WRKY33, could be associated with the differential defense responses induced by the parental and the T3SS mutant strain.

  4. Size growth of red-sequence early-type galaxies in clusters in the last 10 Gyr

    CERN Document Server

    Andreon, S; Raichoor, A

    2016-01-01

    We carried out a photometric and structural analysis in the rest-frame $V$ band of a mass-selected ($\\log M/M_\\odot >10.7$) sample of red-sequence galaxies in 14 galaxy clusters, 6 of which are at $z>1.45$. To this end, we reduced/analyzed about 300 orbits of multicolor images taken with the Advanced Camera for Survey and the Wide Field Camera 3 on the Hubble Space Telescope. We uniformly morphologically classified galaxies from $z=0.023$ to $z=1.803$, and we homogeneously derived sizes (effective radii) for the entire sample. Furthermore, our size derivation allows, and therefore is not biased by, the presence of the usual variety of morphological structures seen in early-type galaxies, such as bulges, bars, disks, isophote twists, and ellipiticy gradients. By using such a mass-selected sample, composed of 244 red-sequence early-type galaxies, we find that the $\\log$ of the galaxy size at a fixed stellar mass, $\\log M/M_\\odot= 11$ has increased with time at a rate of $0.023\\pm0.002$ dex per Gyr over the last...

  5. The Co-Evolution of Total Density Profiles and Central Dark Matter Fractions in Simulated Early-Type Galaxies

    CERN Document Server

    Remus, Rhea-Silvia; Naab, Thorsten; Burkert, Andreas; Hirschmann, Michaela; Hoffmann, Tadziu L; Johansson, Peter H

    2016-01-01

    We present evidence from cosmological hydrodynamical simulations for a co-evolution of the slope of the total (dark and stellar) mass density profiles, gamma_tot, and the dark matter fractions within the half-mass radius, f_DM, in early-type galaxies. The relation can be described as gamma_tot = A f_DM + B and holds for all systems at all redshifts. We test different feedback models and find that the general trend is independent of the assumed feedback processes and is set by the decreasing importance of dissipative processes towards lower redshifts and for more massive systems. Early-type galaxies are smaller, more concentrated, have lower dark matter fractions and steeper total density slopes at high redshifts and at lower masses for a given redshift. The values for A and B change distinctively with the assumed feedback model, and thus this relation can be used as a test for feedback models. A similar correlation exists between gamma_tot and the stellar mass surface density Sigma_*. The model with weak stel...

  6. The Atlas3D Project -- XI. Dense molecular gas properties of CO-luminous early-type galaxies

    CERN Document Server

    Crocker, Alison; Bureau, Martin; Young, Lisa M; Davis, Timothy A; Bayet, Estelle; Alatalo, Katherine; Blitz, Leo; Bois, Maxime; Bournaud, Frédéric; Cappellari, Michele; Davies, Roger L; de Zeeuw, P T; Duc, Pierre-Alain; Emsellem, Eric; Khochfar, Sadegh; Krajnovic, Davor; Kuntschner, Harald; Lablanche, Pierre-Yves; McDermid, Rchard M; Morganti, Raffaella; Naab, Thorsten; Oosterloo, Tom; Sarzi, Marc; Scott, Nicholas; Serra, Paolo; Weijmans, Anne-Marie

    2011-01-01

    Surveying eighteen 12CO-bright galaxies from the ATLAS3D early-type galaxy sample with the Institut de Radio Astronomie Millim\\'etrique (IRAM) 30m telescope, we detect 13CO(1-0) and 13CO(2-1) in all eighteen galaxies, HCN(1-0) in 12/18 and HCO+(1-0) in 10/18. We find that the line ratios 12CO(1-0)/13CO(1-0) and 12CO(1-0)/HCN(1-0) are clearly correlated with several galaxy properties: total stellar mass, luminosity-weighted mean stellar age, molecular to atomic gas ratio, dust temperature and dust morphology. We suggest that these correlations are primarily governed by the optical depth in the 12CO lines; interacting, accreting and/or starbursting early-type galaxies have more optically thin molecular gas while those with settled dust and gas discs host optically thick molecular gas. The ranges of the integrated line intensity ratios generally overlap with those of spirals, although we note some outliers in the 12CO(1- 0)/13CO(1-0), 12CO(2-1)/13CO(2-1) and HCN/HCO+(1-0) ratios. In particular, three galaxies ar...

  7. Early detection of cardiac dysfunction in the type 1 diabetic heart using speckle-tracking based strain imaging.

    Science.gov (United States)

    Shepherd, Danielle L; Nichols, Cody E; Croston, Tara L; McLaughlin, Sarah L; Petrone, Ashley B; Lewis, Sara E; Thapa, Dharendra; Long, Dustin M; Dick, Gregory M; Hollander, John M

    2016-01-01

    Enhanced sensitivity in echocardiographic analyses may allow for early detection of changes in cardiac function beyond the detection limits of conventional echocardiographic analyses, particularly in a small animal model. The goal of this study was to compare conventional echocardiographic measurements and speckle-tracking based strain imaging analyses in a small animal model of type 1 diabetes mellitus. Conventional analyses revealed differences in ejection fraction, fractional shortening, cardiac output, and stroke volume in diabetic animals relative to controls at 6-weeks post-diabetic onset. In contrast, when assessing short- and long-axis speckle-tracking based strain analyses, diabetic mice showed changes in average systolic radial strain, radial strain rate, radial displacement, and radial velocity, as well as decreased circumferential and longitudinal strain rate, as early as 1-week post-diabetic onset and persisting throughout the diabetic study. Further, we performed regional analyses for the LV and found that the free wall region was affected in both the short- and long-axis when assessing radial dimension parameters. These changes began 1-week post-diabetic onset and remained throughout the progression of the disease. These findings demonstrate the use of speckle-tracking based strain as an approach to elucidate cardiac dysfunction from a global perspective, identifying left ventricular cardiac regions affected during the progression of type 1 diabetes mellitus earlier than contractile changes detected by conventional echocardiographic measurements.

  8. The Atlas3D Project - XXX. Star formation histories and stellar population scaling relations of early-type galaxies

    CERN Document Server

    McDermid, Richard M; Blitz, Leo; Bournaud, Frederic; Bureau, Martin; Cappellari, Michele; Crocker, Alison F; Davies, Roger L; Davis, Timothy A; de Zeeuw, P T; Duc, Pierre-Alain; Emsellem, Eric; Khochfar, Sadegh; Krajnovic, Davor; Kuntschner, Harald; Morganti, Raffaella; Naab, Thorsten; Oosterloo, Tom; Sarzi, Marc; Scott, Nicholas; Serra, Paolo; Weijmans, Anne-Marie; Young, Lisa M

    2015-01-01

    We present the stellar population content of early-type galaxies from the Atlas3D survey. Using spectra integrated within apertures covering up to one effective radius, we apply two methods: one based on measuring line-strength indices and applying single stellar population (SSP) models to derive SSP-equivalent values of stellar age, metallicity, and alpha enhancement; and one based on spectral fitting to derive non-parametric star-formation histories, mass-weighted average values of age, metallicity, and half-mass formation timescales. Using homogeneously derived effective radii and dynamically-determined galaxy masses, we present the distribution of stellar population parameters on the Mass Plane (M_JAM, Sigma_e, R_maj), showing that at fixed mass, compact early-type galaxies are on average older, more metal-rich, and more alpha-enhanced than their larger counterparts. From non-parametric star-formation histories, we find that the duration of star formation is systematically more extended in lower mass obje...

  9. Near-Infrared Imaging of Early-Type Galaxies; 4, The Physical Origins of the Fundamental Plane Scaling Relations

    CERN Document Server

    Pahre, M A; Djorgovski, S G

    1998-01-01

    The physical origins of the Fundamental Plane (FP) scaling relations are investigated for early-type galaxies observed at optical and near-infrared wavelengths. The slope for the FP is shown to increase systematically with wavelength from the U-band through the K-band. A distance-independent construction of the observables is described which provides an accurate measurement of the change in the FP slope between any pair of bandpasses. The variation of the FP slope with wavelength is strong evidence of systematic variations in stellar content along the elliptical galaxy sequence. The intercept of the diagnostic relationship between log(D_K/D_V) and log(sigma_0) shows no significant dependence on environment within the uncertainties of the Galactic extinction corrections, demonstrating the universality of the stellar populations contributions at the level of Delta(V-K)=0.03 mag to the zero-point of the global scaling relations. Several other constraints on the properties of early-type galaxies --- the slope of ...

  10. LBT-LUCIFER spectroscopy: kinematics of a compact early type galaxy at z\\simeq1.4

    CERN Document Server

    Longhetti, Marcella; Gargiulo, Adriana; Tamburri, Sonia; Lonoce, Ilaria

    2014-01-01

    We present a high signal to noise (S/N$>$10) medium resolution (R=2000) LBT-LUCIFER spectrum of the early-type galaxy (ETG) S2F1-142 at $z\\simeq1.4$. By means of the CaT line at $8662$ \\AA, we measured its redshift $z=1.386\\pm 0.001$ and we estimated its velocity dispersion $\\sigma_{v}=340 ^{-60}_{+120}$ km/s. Its corresponding virial mass is 3.9$\\times10^{11}$ M$_\\odot$, compatible with the stellar mass estimates obtained assuming Initial Mass Functions (IMFs) less dwarf rich than the Salpeter one. S2F1-142 is a compact galaxy with $R_{e}$=3.1$\\pm$0.2 kpc, i.e., an effective radius more than three times smaller than the average $R_{e}$ of early-type galaxies with the same mass in the local universe. At the same time, we found local and high redshift galaxies with a similar mass content and similar effective radius confirming that it is fully consistent with the already available measures of $R_{e}$ and $\\sigma_{v}$ both in the local and in the distant universe. Considering the distribution of $R_{e}$ and $\\s...

  11. The SLUGGS Survey: revisiting the correlation between X-ray luminosity and total mass of massive early-type galaxies

    CERN Document Server

    Forbes, Duncan A; Romanowsky, Aaron J; Kim, Dong-Woo; Brodie, Jean P; Fabbiano, Giuseppina

    2016-01-01

    Here we utilise recent measures of galaxy total dynamical mass and X-ray gas luminosities (L$_{X,Gas}$) for a sample of 29 massive early-type galaxies from the SLUGGS survey to probe L$_{X,Gas}$--mass scaling relations. In particular, we investigate scalings with stellar mass, dynamical mass within 5 effective radii (R$_e$) and total virial mass. We also compare these relations with predictions from $\\Lambda$CDM simulations. We find a strong linear relationship between L$_{X,Gas}$ and galaxy dynamical mass within 5 R$_e$, which is consistent with the recent cosmological simulations of Choi et al. that incorporate mechanical heating from AGN. We conclude that the gas surrounding massive early-type galaxies was shock heated as it fell into collapsing dark matter halos so that L$_{X,Gas}$ is primarily driven by the depth of a galaxy's potential well. Heating by an AGN plays an important secondary role in determining L$_{X,Gas}$.

  12. The Structure & Dynamics of Massive Early-type Galaxies: On Homology, Isothermality and Isotropy inside one Effective Radius

    CERN Document Server

    Koopmans, L V E; Treu, T; Czoske, O; Auger, M; Barnabe, M; Vegetti, S; Gavazzi, R; Moustakas, L; Burles, S

    2009-01-01

    Based on 58 SLACS strong-lens early-type galaxies to with direct total-mass and stellar-velocity dispersion measurements, we find that inside one effective radius massive elliptical galaxies with M_eff>=3x10^10 M_sun are kinematically almost indistinguishable from an isothermal ellipsoid with an average logaritmic density slope of _LD=dlog(\\rho_tot)/dlog(r)=2.085^{+0.025}_{-0.018} (rand.) (68 percent CL; isotropic orbits with \\beta_r=0), +-0.1 (syst.) and \\sigma_{\\gamma'}_SR=1.959+-0.077. Agreement between the two values is reached for =0.45+-0.25, consistent with mild radial anisotropy. This agreement supports the robustness of our results, despite the increase in mass-to-light ratio with total galaxy mass: M_eff ~ L_{V,eff}^(1.363+-0.056). We conclude that massive early-type galaxies are structurally close-to homologous with close-to isothermal total density profiles (<=10 percent scatter) and have at most some mild radial anisotropy. Our results provide tight observational limits on galaxy formation and...

  13. H-ATLAS/GAMA and HeViCS - Dusty Early-Type Galaxies in Different Environments

    CERN Document Server

    Agius, N K; Viaene, S; Baes, M; Sansom, A E; Bourne, N; Bland-Hawthorn, J; Brough, S; Davis, T A; De Looze, I; Driver, S P; Dunne, L; Dye, S; Eales, S A; Hughes, T M; Ivison, R J; Kelvin, L S; Maddox, S; Mahajan, S; Pappalardo, C; Robotham, A S G; Rowlands, K; Valiante, P Temi E

    2015-01-01

    The Herschel Space Observatory has had a tremendous impact on the study of extragalactic dust. Specifically, early-type galaxies (ETG) have been the focus of several studies. In this paper we combine results from two Herschel studies - a Virgo cluster study HeViCS and a broader, low-redshift H-ATLAS/GAMA study - and contrast the dust and associated properties for similar mass galaxies. This comparison is motivated by differences in results exhibited between multiple Herschel studies of early-type galaxies. A comparison between consistent modified blackbody derived dust mass is carried out, revealing strong differences between the two samples in both dust mass and dust-to-stellar mass ratio. In particular, the HeViCS sample lacks massive ETG with as high a specific dust content as found in H-ATLAS. This is most likely connected with the difference in environment for the two samples. We calculate nearest neighbour environment densities in a consistent way, showing that H-ATLAS ETG occupy sparser regions of the ...

  14. Improved Early Crop Type Identification By Joint Use of High Temporal Resolution SAR And Optical Image Time Series

    Directory of Open Access Journals (Sweden)

    Jordi Inglada

    2016-04-01

    Full Text Available High temporal and spatial resolution optical image time series have been proven efficient for crop type mapping at the end of the agricultural season. However, due to cloud cover and image availability, crop identification earlier in the season is difficult. The recent availability of high temporal and spatial resolution SAR image time series, opens the possibility of improving early crop type mapping. This paper studies the impact of such SAR image time series when used in complement of optical imagery. The pertinent SAR image features, the optimal working resolution, the effect of speckle filtering and the use of temporal gap-filling of the optical image time series are assessed. SAR image time series as those provided by the Sentinel-1 satellites allow significant improvements in terms of land cover classification, both in terms of accuracy at the end of the season and for early crop identification. Haralik textures (Entropy, Inertia, the polarization ratio and the local mean together with the VV imagery were found to be the most pertinent features. Working at at 10 m resolution and using speckle filtering yield better results than other configurations. Finally it was shown that the use of SAR imagery allows to use optical data without gap-filling yielding results which are equivalent to the use of gap-filling in the case of perfect cloud screening, and better results in the case of cloud screening errors.

  15. Early-phase photometry and spectroscopy of transitional Type Ia SN 2012ht: Direct constraint on the rise time

    CERN Document Server

    Yamanaka, Masayuki; Kawabata, Miho; Tanaka, Masaomi; Takaki, Katsutoshi; Ueno, Issei; Masumoto, Kazunari; Kawabata, Koji S; Itoh, Ryosuke; Moritani, Yuki; Akitaya, Hiroshi; Arai, Akira; Honda, Satoshi; Nishiyama, Koichi; Kabashima, Fumio; Matsumoto, Katsura; Nogami, Daisaku; Yoshida, Michitoshi

    2014-01-01

    We report photometric and spectroscopic observations of the nearby Type Ia Supernova (SN Ia) 2012ht from $-15.8$ days to $+49.1$ days after $B$-band maximum. The decline rate of the light curve is $\\Delta m_{15}$($B$)$=1.39~\\pm~0.05$ mag, which is intermediate between normal and subluminous SNe Ia, and similar to that of the `transitional' Type Ia SN 2004eo. The spectral line profiles also closely resemble those of SN 2004eo. We were able to observe SN 2012ht at very early phase, when it was still rising and was about three magnitudes fainter than at the peak. The rise time to the $B$-band maximum is estimated to be $17.6 \\pm 0.5$ days and the time of the explosion is MJD $56277.98 \\pm 0.13$. SN 2012ht is the first transitional SN Ia whose rise time is directly measured without using light curve templates, and the fifth SN Ia overall. This rise time is consistent with those of the other four SNe within the measurement error, even including the extremely early detection of SN 2013dy. The rising part of the lig...

  16. The Afterglow and Early-Type Host Galaxy of the Short GRB 150101B at z=0.1343

    CERN Document Server

    Fong, Wen-fai; Chornock, Ryan; Berger, Edo; Shappee, Benjamin J; Levan, Andrew J; Tanvir, Nial R; Smith, Nathan; Milne, Peter A; Laskar, Tanmoy; Fox, Derek B; Lunnan, Ragnhild; Blanchard, Peter K; Hjorth, Jens; Wiersema, Klaas; van der Horst, Alexander J; Zaritsky, Dennis

    2016-01-01

    We present the discovery of the X-ray and optical afterglows of the short-duration GRB 150101B, pinpointing the event to an early-type host galaxy at z=0.1343 +/- 0.0030. This makes GRB 150101B the most nearby short GRB with an early-type host galaxy discovered to date. Fitting the spectral energy distribution of the host galaxy results in an inferred stellar mass of ~7x10^10 M_sol, stellar population age of ~2-2.5 Gyr, and star formation rate of 9 deg. Using observations extending to ~30 days, we place upper limits of <(2-4)x10^41 erg s^-1 on associated kilonova emission. We compare searches following previous short GRBs to existing kilonova models, and demonstrate the difficulty of performing effective kilonova searches from cosmological short GRBs using current ground-based facilities. We show that at the Advanced LIGO/VIRGO horizon distance of 200 Mpc, searches reaching depths of ~23-24 AB mag are necessary to probe a meaningful range of kilonova models.

  17. Radial Trends in IMF-Sensitive Absorption Features in Two Early-Type Galaxies: Evidence for Abundance-Driven Gradients

    CERN Document Server

    McConnell, Nicholas J; Mann, Andrew W

    2015-01-01

    We have observed two massive early-type galaxies with Keck/LRIS and measured radial gradients in the strengths of stellar absorption features from 4000-5500 \\AA$\\,$ and 8000-10,000 \\AA. We present spatially resolved measurements of the dwarf-sensitive spectral indices NaI (8190 \\AA) and Wing-Ford FeH (9915 \\AA), as well as indices for species of H, C$_2$, CN, Mg, Ca, TiO, and Fe. Our measurements show a metallicity gradient in both objects, and Mg/Fe consistent with uniform $\\alpha$-enhancement, matching widely observed trends for massive early-type galaxies. The NaI index and the CN$_1$ index at 4160 \\AA$\\,$ exhibit significantly steeper gradients, with a break at $r \\sim 0.1 r_{\\rm eff}$ ($r \\sim 300$ pc). Inside this radius NaI and CN$_1$ increase sharply toward the galaxy center, relative to other indices. We interpret this trend as a rapid central rise in [Na/Fe] and [N/Fe]. In contrast, the FeH index exhibits a marginal decrease toward the galaxy center, relative to Fe. Our investigation is among the fi...

  18. IMF and [Na/Fe] abundance ratios from optical and NIR Spectral Features in Early-type Galaxies

    CERN Document Server

    La Barbera, F; Ferreras, I; Pasquali, A; Prieto, C Allende; Rock, B; Aguado, D S; Peletier, R F

    2016-01-01

    We present a joint analysis of the four most prominent sodium-sensitive features (NaD, NaI8190, NaI1.14, and NaI2.21), in the optical and Near-Infrared spectral range, of two nearby, massive (sigma~300km/s), early-type galaxies (named XSG1 and XSG2). Our analysis relies on deep VLT/X-Shooter long-slit spectra, along with newly developed stellar population models, allowing for [Na/Fe] variations, up to 1.2dex, over a wide range of age, total metallicity, and IMF slope. The new models show that the response of the Na-dependent spectral indices to [Na/Fe] is stronger when the IMF is bottom heavier. For the first time, we are able to match all four Na features in the central regions of massive early-type galaxies, finding an overabundance of [Na/Fe], in the range 0.5-0.7dex, and a bottom-heavy IMF. Therefore, individual abundance variations cannot be fully responsible for the trends of gravity-sensitive indices, strengthening the case towards a non-universal IMF. Given current limitations of theoretical atmospher...

  19. The SAURON project - XV. Modes of star formation in early-type galaxies and the evolution of the red sequence

    CERN Document Server

    Shapiro, K L; van de Ven, G; de Zeeuw, P T; Sarzi, M; Bacon, R; Bolatto, A; Cappellari, M; Croton, D; Davies, R L; Emsellem, E; Fakhouri, O; Krajnovic, D; Kuntschner, H; McDermid, R M; Peletier, R F; Bosch, R C E van den; van der Wolk, G

    2009-01-01

    We combine SAURON integral field data of a representative sample of local early-type, red sequence galaxies with Spitzer/IRAC imaging in order to investigate the presence of trace star formation in these systems. With the Spitzer data, we identify galaxies hosting low-level star formation, as traced by PAH emission, with measured star formation rates that compare well to those estimated from other tracers. This star formation proceeds according to established scaling relations with molecular gas content, in surface density regimes characteristic of disk galaxies and circumnuclear starbursts. We find that star formation in early-type galaxies happens exclusively in fast-rotating systems and occurs in two distinct modes. In the first, star formation is a diffuse process, corresponding to widespread young stellar populations and high molecular gas content. The equal presence of co- and counter-rotating components in these systems strongly implies an external origin for the star-forming gas, and we argue that the...

  20. VEGAS: A VST Early-type GAlaxy Survey. I. Presentation, wide-field surface photometry, and substructures in NGC 4472

    CERN Document Server

    Capaccioli, Massimo; Grado, Aniello; Iodice, Enrichetta; Limatola, Luca; Napolitano, Nicola R; Cantiello, Michele; Paolillo, Maurizio; Romanowsky, Aaron J; Forbes, Duncan A; Puzia, Thomas H; Raimondo, Gabriella; Schipani, Pietro

    2015-01-01

    We present the VST Early-type GAlaxy Survey (VEGAS), which is designed to obtain deep multiband photometry in g, r, i, of about one hundred nearby galaxies down to 27.3, 26.8, and 26 mag/arcsec^2 respectively, using the ESO facility VST/OmegaCAM.} The goals of the survey are 1) to map the light distribution up to ten effective radii, r_e, 2) to trace color gradients and surface brightness fluctuation gradients out to a few r_e for stellar population characterization, and 3) to obtain a full census of the satellite systems (globular clusters and dwarf galaxies) out to 20% of the galaxy virial radius. The external regions of galaxies retain signatures of the formation and evolution mechanisms that shaped them, and the study of nearby objects enables a detailed analysis of their morphology and interaction features. To clarify the complex variety of formation mechanisms of early-type galaxies (ETGs), wide and deep photometry is the primary observational step, which at the moment has been pursued with only a few d...

  1. Merger-driven evolution of the effective stellar initial mass function of massive early-type galaxies

    Science.gov (United States)

    Sonnenfeld, Alessandro; Nipoti, Carlo; Treu, Tommaso

    2017-02-01

    The stellar initial mass function (IMF) of early-type galaxies is the combination of the IMF of the stellar population formed in situ and that of accreted stellar populations. Using as an observable the effective IMF αIMF, defined as the ratio between the true stellar mass of a galaxy and the stellar mass inferred assuming a Salpeter IMF, we present a theoretical model for its evolution as a result of dry mergers. We use a simple dry-merger evolution model, based on cosmological N-body simulations, together with empirically motivated prescriptions for the IMF to make predictions on how the effective IMF of massive early-type galaxies changes from z = 2 to z = 0. We find that the IMF normalization of individual galaxies becomes lighter with time. At fixed velocity dispersion, αIMF is predicted to be constant with redshift. Current dynamical constraints on the evolution of the IMF are in slight tension with this prediction, even though systematic uncertainties, including the effect of radial gradients in the IMF, prevent a conclusive statement. The correlation of αIMF with stellar mass becomes shallower with time, while the correlation between αIMF and velocity dispersion is mostly preserved by dry mergers. We also find that dry mergers can mix the dependence of the IMF on stellar mass and velocity dispersion, making it challenging to infer, from z = 0 observations of global galactic properties, what is the quantity that is originally coupled with the IMF.

  2. Merger-driven evolution of the effective stellar initial mass function of massive early-type galaxies

    CERN Document Server

    Sonnenfeld, Alessandro; Treu, Tommaso

    2016-01-01

    The stellar initial mass function (IMF) of early-type galaxies is the combination of the IMF of the stellar population formed in-situ and that of accreted stellar populations. Using as an observable the effective IMF $\\alpha_{IMF}$, defined as the ratio between the true stellar mass of a galaxy and the stellar mass inferred assuming a Salpeter IMF, we present a theoretical model for its evolution as a result of dry mergers. We use a simple dry merger evolution model, based on cosmological $N$-body simulations, together with empirically motivated prescriptions for the IMF to make predictions for how the effective IMF of massive early-type galaxies changes from $z=2$ to $z=0$. We find that the IMF normalization of individual galaxies becomes lighter with time. At fixed velocity dispersion, $\\alpha_{IMF}$ is predicted to be constant with redshift. Current constraints on the evolution of the IMF are in slight tension with this prediction, even though systematic uncertainties prevent a conclusive statement. The co...

  3. Unusual Red Sea-Type GDGT Distributions during the Early Paleogene: A Proxy for Enhanced Salinity?

    Science.gov (United States)

    Pancost, R. D.; Inglis, G.; Farnsworth, A.; Lunt, D. J.; Foster, G. L.; Hollis, C. J.; Jardine, P. E.

    2014-12-01

    TEX86, an organic palaeothermometer based upon the distribution of isoprenoidal glycerol dialkyl glycerol tetraethers (GDGTs) in marine Thaumarchaeota, is regularly used to reconstruct spatial and temporal sea surface temperature patterns, especially in older (Mesozoic and Palaeogene) settings. The TEX86 proxy assumes that Thaumarchaeota in modern oceans are representative of those living in ancient settings, but even in today's oceans Thaumarchaeotal phylogeny is diverse. In the Red Sea, phylogenetically distinct archaeal communities occur both above and below the thermocline and correspond to core-top sediments in which TEX86 values consistently overestimate satellite-derived sea surface temperature (SST) by 6-8°C [1]. These elevated SSTs are associated with an unusual GDGT distribution characterised by low GDGT-0 (10%). Here we propose the %GDGTRS index (= ([GDGT-4']/[GDGT-4']+[GDGT-0])*100) as a way to identify Red Sea-type GDGT distributions in ancient sediments. In a Paleogene (65-34Ma) compilation, Red Sea-type GDGT distributions are common and geographically widespread, and could lead to SST overestimates. The underlying ecological controls that govern the occurrence of these distributions remain unclear, but they are especially common during times of elevated warmth (i.e. EECO, PETM). During the EECO and the PETM, the occurrence of Red Sea-type GDGT distributions coincides with the presence of hypersaline and/or lagoonal dinocysts in at least four global localities. We suggest that the high %GDGTRS values during these very hot intervals reflect the presence of unique Thaumarchaeotal or Euryarchaeotal clusters responding to the development of more saline conditions, similar to or perhaps exceeding those observed in the Red Sea today. 1. Trommer, G. et al., 2009. Distribution of Crenarchaeota tetraether membrane lipids in surface sediments from the Red Sea. Organic Geochemistry, v. 40, p. 724-731

  4. An exploration of links between early parenting experiences and personality disorder type and disordered personality functioning.

    Science.gov (United States)

    Parker, G; Roy, K; Wilhelm, K; Mitchell, P; Austin, M P; Hadzi-Pavlovic, D

    1999-01-01

    Reports of early parenting were assessed using two measures, the Parental Bonding Index (PBI) and the Measure of Parenting Style (MOPS), in a sample of 265 patients with DSM-defined major depressive disorder. Psychiatrists then rated the extent to which sample members evidenced the personality "styles" underpinning 15 separate personality disorders, returning personality vignette scores. The extent of disordered functioning was also assessed across "parameters" and "domains" by psychiatrists, referrers, and family members, using a range of measures. Those with higher scores on vignettes measuring borderline, anxious, depressive, and self-defeating personality style rated parents as uncaring, overcontrolling, and abusive. When vignettes were consolidated into scores akin to the DSM clusters, the most consistent links between perceived dysfunctional parenting were with the Cluster C (anxious), and Cluster B (dramatic) styles and were nonsignificant for Cluster A (eccentric) style. Meeting criteria for an increasing number of personality disorder clusters was associated with increasing levels of adverse parenting. Multiple regression analyses indicated that disordered functioning (as assessed by the three independent rater groups) was most distinctly associated with paternal indifference and maternal overcontrol.

  5. Early UV/Optical Emission of The Type Ib SN 2008D

    CERN Document Server

    Bersten, Melina C; Tominaga, Nozomu; Benvenuto, Omar G; Nomoto, Ken'ichi

    2013-01-01

    We propose an alternative explanation for the post-breakout emission of SN 2008D associated with the X-ray transient 080109. Observations of this object show a very small contrast of 0.35 dex between the light-curve minimum occurring soon after the breakout, and the main luminosity peak that is due to radioactive heating of the ejecta. Hydrodynamical models show that the cooling of a shocked Wolf-Rayet star leads to a much greater difference (> 0.9 dex). Our proposed scenario is that of a jet produced during the explosion which deposits 56Ni-rich material in the outer layers of the ejecta. The presence of high-velocity radioactive material allows us to reproduce the complete luminosity evolution of the object. Without outer 56Ni it could be possible to reproduce the early emission purely from cooling of the shocked envelope by assuming a larger progenitor than a Wolf-Rayet star, but that would require an initial density structure significantly different from what is predicted by stellar evolution models. Anal...

  6. Evaluation of Early Markers of Nephropathy in Patients with Type 2 Diabetes Mellitus

    Directory of Open Access Journals (Sweden)

    Pierina De Muro

    2016-01-01

    Full Text Available Aims. T2DM often remains undiagnosed for many years because hyperglycemia develops gradually and may not produce any symptoms. As patients with T2DM are at increased risk of microvascular and macrovascular complications, the preclinical diagnosis of the state is the key point of the disease management. Methods. We evaluated parameters such as GAGs/PGs, NAG, and NGAL in urine samples from 43 normoalbuminuric T2DM patients and 31 apparently healthy control subjects. Results. The total urinary GAG excretion showed no significant differences between patients and controls. The electrophoretic analysis evidenced the presence of UTI and its degradation products (LSC and SM-LSC, CS, and HS. We observed modifications of HS and total UTI (including UTI and its degradation products relative contents in T2DM patients compared with controls whereas no differences in CS percentage were found. NGAL levels were significantly increased in T2DM patients and were positively correlated with both NAG (r=0.606, p<0.0001 and the presence of hypertension (r=0.352, p<0.05. Conclusions. These data suggest that the assessed molecules could represent useful markers to detect early renal impairment in patients with T2DM.

  7. Insulin Therapy with Personal Insulin Pumps and Early Angiopathy in Children with Type 1 Diabetes Mellitus

    Directory of Open Access Journals (Sweden)

    Joanna Tołwińska

    2013-01-01

    Full Text Available Objective. Assessment of the effect of a treatment method change from multiple daily insulin injection (MDI to continuous subcutaneous insulin infusion (CSII on the development of early angiopathy in children with T1DM with or without retinopathy. Methods. The study pump group involved 32 diabetic children aged 14.8, with the initial HbA1c level of 8.3%, previously treated by MDI. The patients were examined before pump insertion and after 3 and 6 months of CSII. We assessed HbA1c level, carotid artery intima-media thickness (c-IMT, and flow-mediated dilatation (FMD of the brachial artery. The pump group was compared to a group of eight teenagers with diagnosed nonproliferative retinopathy, treated with MDI. Results. HbA1c in the entire group was found to improve in the second and in the third examination. During 6 months of CSII, FMD increased and IMT decreased. Retinopathic adolescents had significantly thicker IMT and lower FMD compared to baseline results of the pump group. Treatment intensification in the retinopathy-free children enhanced these differences. Conclusions. CSII is associated with lower IMT and higher FMD. Whether on the long-run CSII is superior to MDI to delay the occurrence of diabetes late complications remains to be explained.

  8. Plasma free amino acid profiling of five types of cancer patients and its application for early detection.

    Directory of Open Access Journals (Sweden)

    Yohei Miyagi

    Full Text Available BACKGROUND: Recently, rapid advances have been made in metabolomics-based, easy-to-use early cancer detection methods using blood samples. Among metabolites, profiling of plasma free amino acids (PFAAs is a promising approach because PFAAs link all organ systems and have important roles in metabolism. Furthermore, PFAA profiles are known to be influenced by specific diseases, including cancers. Therefore, the purpose of the present study was to determine the characteristics of the PFAA profiles in cancer patients and the possibility of using this information for early detection. METHODS AND FINDINGS: Plasma samples were collected from approximately 200 patients from multiple institutes, each diagnosed with one of the following five types of cancer: lung, gastric, colorectal, breast, or prostate cancer. Patients were compared to gender- and age- matched controls also used in this study. The PFAA levels were measured using high-performance liquid chromatography (HPLC-electrospray ionization (ESI-mass spectrometry (MS. Univariate analysis revealed significant differences in the PFAA profiles between the controls and the patients with any of the five types of cancer listed above, even those with asymptomatic early-stage disease. Furthermore, multivariate analysis clearly discriminated the cancer patients from the controls in terms of the area under the receiver-operator characteristics curve (AUC of ROC >0.75 for each cancer, regardless of cancer stage. Because this study was designed as case-control study, further investigations, including model construction and validation using cohorts with larger sample sizes, are necessary to determine the usefulness of PFAA profiling. CONCLUSIONS: These findings suggest that PFAA profiling has great potential for improving cancer screening and diagnosis and understanding disease pathogenesis. PFAA profiles can also be used to determine various disease diagnoses from a single blood sample, which involves a

  9. Type 2 diabetes mellitus and prognosis in early stage breast cancer women.

    Science.gov (United States)

    Kaplan, Muhammet Ali; Pekkolay, Zafer; Kucukoner, Mehmet; Inal, Ali; Urakci, Zuhat; Ertugrul, Hamza; Akdogan, Recai; Firat, Ugur; Yildiz, Ismail; Isikdogan, Abdurrahman

    2012-09-01

    It has been suggested that type 2 diabetes mellitus may affect breast cancer prognosis, possibly due to increased diabetes-related comorbidity, or direct effects of insulin resistance and/or hyperinsulinemia. The aim of this study was to determine the impact of diabetes on disease-free survival (DFS) following mastectomy for breast cancer patients. The cases included in this retrospective study were selected from breast cancer women who had undergone mastectomy and completed adjuvant chemotherapy from 1998 to 2010. Patients were classified into two groups: diabetic and non-diabetic. Patients' age, sex, menopausal status, body mass index (BMI), histopathological features, tumor size, lymph node involvement, hormone receptor and HER2-neu status, and treatment types were recorded. There were 483 breast cancer patients included in the study. Postmenopausal patients' rate (53.7% vs. 36.8%, P = 0.016) and mean BMI levels were statistically higher (32.2 vs. 27.9, P = 0.007) in diabetic patients. There was no statistical difference for histological subgroup, grade, ER and PR positivity, HER2-neu overexpression rate, and tumor size between the diabetic and non-diabetic group. Lymph node involvements were statistically higher in diabetic patients compared with non-diabetic patients (P = 0.013). Median disease-free survival is 81 months (95% CI, 61.6-100.4) in non-diabetic patients and 36 months (95% CI, 13.6-58.4) in diabetic patients (P breast cancer.

  10. Early human herpes virus type 6 reactivation in umbilical cord blood allogeneic stem cell transplantation.

    Science.gov (United States)

    Cirrone, Frank; Ippoliti, Cindy; Wang, Hanhan; Zhou, Xi Kathy; Gergis, Usama; Mayer, Sebastian; Shore, Tsiporah; van Besien, Koen

    2016-11-01

    Human herpes virus type 6 can reactivate in patients after allogeneic stem cell transplantation and has been associated with serious sequelae such as delayed engraftment and an increased risk of developing acute graft-versus-host disease (GVHD). This study investigated human herpes virus type 6 (HHV-6) reactivation within 60 days of transplantation in stem cell transplants utilizing single umbilical cord blood, double umbilical cord blood, or umbilical cord blood plus haploidentical stem cells. Of 92 patients, 60 (65%) had HHV-6 reactivation. Reactivation was not significantly influenced by any patient characteristics, disease characteristics, or by stem cell source (umbilical cord blood only versus haploidentical plus umbilical cord blood). We did not observe any impact of HHV-6 reactivation on neutrophil or platelet count recovery or on relapse-free survival. HHV-6 reactivation was associated with subsequent development of prerelapse acute GVHD (HR = 3.00; 95% CI, 1.4 to 6.4; p = 0.004).

  11. Early-life origins of type 2 diabetes: fetal programming of the beta-cell mass.

    Science.gov (United States)

    Portha, Bernard; Chavey, Audrey; Movassat, Jamileh

    2011-01-01

    A substantial body of evidence suggests that an abnormal intrauterine milieu elicited by maternal metabolic disturbances as diverse as undernutrition, placental insufficiency, diabetes or obesity, may program susceptibility in the fetus to later develop chronic degenerative diseases, such as obesity, hypertension, cardiovascular diseases and diabetes. This paper examines the developmental programming of glucose intolerance/diabetes by disturbed intrauterine metabolic condition experimentally obtained in various rodent models of maternal protein restriction, caloric restriction, overnutrition or diabetes, with a focus on the alteration of the developing beta-cell mass. In most of the cases, whatever the type of initial maternal metabolic stress, the beta-cell adaptive growth which normally occurs during gestation, does not take place in the pregnant offspring and this results in the development of gestational diabetes. Therefore gestational diabetes turns to be the ultimate insult targeting the offspring beta-cell mass and propagates diabetes risk to the next generation again. The aetiology and the transmission of spontaneous diabetes as encountered in the GK/Par rat model of type 2 diabetes, are discussed in such a perspective. This review also discusses the non-genomic mechanisms involved in the installation of the programmed effect as well as in its intergenerational transmission.

  12. Early-Life Origins of Type 2 Diabetes: Fetal Programming of the Beta-Cell Mass

    Directory of Open Access Journals (Sweden)

    Bernard Portha

    2011-01-01

    Full Text Available A substantial body of evidence suggests that an abnormal intrauterine milieu elicited by maternal metabolic disturbances as diverse as undernutrition, placental insufficiency, diabetes or obesity, may program susceptibility in the fetus to later develop chronic degenerative diseases, such as obesity, hypertension, cardiovascular diseases and diabetes. This paper examines the developmental programming of glucose intolerance/diabetes by disturbed intrauterine metabolic condition experimentally obtained in various rodent models of maternal protein restriction, caloric restriction, overnutrition or diabetes, with a focus on the alteration of the developing beta-cell mass. In most of the cases, whatever the type of initial maternal metabolic stress, the beta-cell adaptive growth which normally occurs during gestation, does not take place in the pregnant offspring and this results in the development of gestational diabetes. Therefore gestational diabetes turns to be the ultimate insult targeting the offspring beta-cell mass and propagates diabetes risk to the next generation again. The aetiology and the transmission of spontaneous diabetes as encountered in the GK/Par rat model of type 2 diabetes, are discussed in such a perspective. This review also discusses the non-genomic mechanisms involved in the installation of the programmed effect as well as in its intergenerational transmission.

  13. Effect of early intensive multifactorial therapy on 5-year cardiovascular outcomes in individuals with type 2 diabetes detected by screening (ADDITION-Europe)

    DEFF Research Database (Denmark)

    Griffin, Simon J; Borch-Johnsen, Knut; Davies, Melanie J

    2011-01-01

    Intensive treatment of multiple cardiovascular risk factors can halve mortality among people with established type 2 diabetes. We investigated the effect of early multifactorial treatment after diagnosis by screening....

  14. Biomarkers for early diagnosis of type 2 diabetic nephropathy: a study based on an integrated biomarker system.

    Science.gov (United States)

    Huang, Min; Liang, Qionglin; Li, Ping; Xia, Jianfei; Wang, Yong; Hu, Ping; Jiang, Zhiting; He, Yongxin; Pang, Liqiong; Han, Lida; Wang, Yiming; Luo, Guoan

    2013-08-01

    Diabetic nephropathy is a devastating disease that affects a growing number of diabetic patients. A complete cure is very hard to achieve once the disease has been diagnosed, therefore the diagnosis of early stages in diabetic nephropathy has become a hot area. Numbers of molecules have been proposed to be potential biomarkers for this purpose. However, some problems still remain, such as discovering effective biomarkers to diagnose the disease before obvious clinical evidence appears. Thus, the main purpose of this study was to find plasma biomarkers for early diagnosis of type 2 diabetic nephropathy stage 1 and stage 2, as well as separating them from diabetes. 182 subjects (Chinese) were recruited for this study, including 50 healthy controls, 33 type 2 diabetic patients and 99 type 2 diabetic nephropathy patients (33 of these were stage 3). Important clinical indicators including proteinuria, serum creatinine, and urea nitrogen were measured and the glomerular filtration rate was estimated to assess kidney function; fasting blood glucose, postprandial blood glucose and glycated hemoglobin were measured to assess the blood glucose control. Key metabolites and genes in plasma samples were identified and determined using -omic and quantitative techniques. The potential biomarkers were then combined and carefully screened to determine the most informative ones for early diagnosis of type 2 diabetic nephropathy. An integrated biomarker system (IBS) incorporating 6 clinical indicators, 40 metabolites and 5 genes was established. Correlation analysis results revealed that most of the potential biomarkers significantly correlated with the 6 clinical indicators. Discriminant analysis results showed that the developed IBS gave the highest total predictive accuracy (98.9%). Significant test and receiver operating characteristic analysis results indicated that inosine had the highest sensitivity (0.889), specificity (1.000), positive predictive rate (1.000) and negative

  15. Prevention or early cure of type 1 diabetes by intranasal administration of gliadin in NOD mice

    DEFF Research Database (Denmark)

    Funda, David; Fundova, Petra; Hansen, Axel Kornerup;

    2014-01-01

    gluten-free diets prevent T1D in animal models. Herewith we investigated whether intranasal (i.n.) administration of gliadin or gluten may arrest the diabetogenic process. I.n. administration of gliadin to 4-week-old NOD mice significantly reduced the diabetes incidence. Similarly, the insulitis......Induction of long-term tolerance to β-cell autoantigens has been investigated both in animal models and in human type 1 diabetes (T1D) in order to prevent the disease. As regards external compounds, the dietary plant protein fraction has been associated with high penetrance of the disease, whereas...... was lowered. Intranasal gliadin also rescued a fraction of prediabetic 13-week-old NOD mice from progressing to clinical onset of diabetes compared to OVA-treated controls. Vaccination with i.n. gliadin led to an induction of CD4+Foxp3+ T cells and even more significant induction of γδ T cells in mucosal...

  16. The early gaseous and stellar mass assembly of Milky Way-type galaxy halos

    Science.gov (United States)

    Hensler, Gerhard; Petrov, Mykola

    2016-08-01

    How the Milky Way has accumulated its mass over the Hubble time, whether significant amounts of gas and stars were accreted from satellite galaxies, or whether the Milky Way has experienced an initial gas assembly and then evolved more-or-less in isolation is one of the burning questions in modern astronomy, because it has consequences for our understanding of galaxy formation in the cosmological context. Here we present the evolutionary model of a Milky Way-type satellite system zoomed into a cosmological large-scale simulation. Embedded into Dark Matter halos and allowing for baryonic processes these chemo-dynamical simulations aim at studying the gas and stellar loss from the satellites to feed the Milky Way halo and the stellar chemical abundances in the halo and the satellite galaxies.

  17. The early gaseous and stellar mass assembly of Milky Way-type galaxy halos

    CERN Document Server

    Hensler, Gerhard

    2016-01-01

    How the Milky Way has accumulated its mass over the Hubble time, whether significant amounts of gas and stars were accreted from satellite galaxies, or whether the Milky Way has experienced an initial gas assembly and then evolved more-or-less in isolation is one of the burning questions in modern astronomy, because it has consequences for our understanding of galaxy formation in the cosmological context. Here we present the evolutionary model of a Milky Way-type satellite system zoomed into a cosmological large-scale simulation. Embedded into Dark Matter halos and allowing for baryonic processes these chemo-dynamical simulations aim at studying the gas and stellar loss from the satellites to feed the Milky Way halo and the stellar chemical abundances in the halo and the satellite galaxies.

  18. Early renal abnormalities as an indicator of cardiovascular risk in type 2 diabetes.

    Science.gov (United States)

    Viazzi, Francesca; Bonino, Barbara; Ratto, Elena; De Cosmo, Salvatore; Pontremoli, Roberto

    2014-12-01

    Accurate assessment of cardiovascular (CV) risk is a prerequisite for devising effective therapeutic strategies in patients with type 2 diabetes (T2DM) as it allows to refine prognosis and treatment targets as well as the cost-benefit ratio for specific pharmacological interventions. The presence of subclinical vascular organ damage plays a well known role in determining overall risk and a wider use of low cost, easy to perform diagnostic tools to stratify CV risk is very much needed. Besides their well known prognostic value for progression to end stage renal disease (ESRD), subclinical renal abnormalities such as microalbuminuria and/or a slight reduction in estimation of glomerular filtration rate (eGFR), have been shown to be powerful, independent predictors of CV diseases in patients with T2DM. Through the combined evaluation of these two biomarkers of chronic kidney disease (CKD), clinicians can usefully and reliably get a perspective on global and CV outcome of their diabetic patients.

  19. Combination of adjuvant chemotherapy and radiotherapy is associated with improved survival at early stage type II endometrial cancer and carcinosarcoma.

    Science.gov (United States)

    Sozen, Hamdullah; Çiftçi, Rumeysa; Vatansever, Dogan; Topuz, Samet; Iyibozkurt, Ahmet Cem; Bozbey, Hamza Ugur; Yaşa, Cenk; Çali, Halime; Yavuz, Ekrem; Kucucuk, Seden; Aydiner, Adnan; Salihoglu, Yavuz

    2016-04-01

    The aim of this study was to describe the impact of postoperative adjuvant treatment modalities and identify risk factors associated with recurrence and survival rates in women diagnosed with early stage type II endometrial cancer and carcinosarcoma. In this retrospective study, patients diagnosed with early stage (stages I-II) carcinosarcoma and type II endometrial cancer were reviewed. All women underwent comprehensive surgical staging. Postoperative treatment options of chemotherapy (CT), radiotherapy (RT), observation (OBS) and chemotherapy-radiotherapy (CT-RT) combination were compared in terms of recurrence and survival outcome. In CT-RT treatment arm, recurrence rate was found as 12.5% and this result is significantly lower than the other treatment approaches (P = 0.01 CT alone: 33.3%, RT alone: 26.7%, OBS: 62.5%). Three-year disease free survival(DFS) rate and overall survival (OS) rate were statistically higher for the group of women treated with combination of CT-RT (92-95%) compared to the women treated with RT alone (65-72%), treated with CT alone (67-74%) and women who received no adjuvant therapy (38-45%). The multivariate analysis revealed that carcinosarcoma histology was associated with shortened DFS and OS (P = 0.001, P = 0.002). On the other hand, being at stage Ia (P = 0.01, P = 0.04) and receiving adjuvant treatment of CT-RT combination (P = 0.005, P = 0.002) appeared to lead to increased DFS and OS rates. We identified that a combination treatment of chemotherapy and radiotherapy is superior compared to other postoperative adjuvant treatment approaches concerning PFS, OS and recurrence rates in stages I-II of type II endometrial cancers and uterine carcinosarcoma. © 2016 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists.

  20. SPOC1-Mediated Antiviral Host Cell Response Is Antagonized Early in Human Adenovirus Type 5 Infection

    Science.gov (United States)

    Schreiner, Sabrina; Kinkley, Sarah; Bürck, Carolin; Mund, Andreas; Wimmer, Peter; Schubert, Tobias; Groitl, Peter; Will, Hans; Dobner, Thomas

    2013-01-01

    Little is known about immediate phases after viral infection and how an incoming viral genome complex counteracts host cell defenses, before the start of viral gene expression. Adenovirus (Ad) serves as an ideal model, since entry and onset of gene expression are rapid and highly efficient, and mechanisms used 24–48 hours post infection to counteract host antiviral and DNA repair factors (e.g. p53, Mre11, Daxx) are well studied. Here, we identify an even earlier host cell target for Ad, the chromatin-associated factor and epigenetic reader, SPOC1, recently found recruited to double strand breaks, and playing a role in DNA damage response. SPOC1 co-localized with viral replication centers in the host cell nucleus, interacted with Ad DNA, and repressed viral gene expression at the transcriptional level. We discovered that this SPOC1-mediated restriction imposed upon Ad growth is relieved by its functional association with the Ad major core protein pVII that enters with the viral genome, followed by E1B-55K/E4orf6-dependent proteasomal degradation of SPOC1. Mimicking removal of SPOC1 in the cell, knock down of this cellular restriction factor using RNAi techniques resulted in significantly increased Ad replication, including enhanced viral gene expression. However, depletion of SPOC1 also reduced the efficiency of E1B-55K transcriptional repression of cellular promoters, with possible implications for viral transformation. Intriguingly, not exclusive to Ad infection, other human pathogenic viruses (HSV-1, HSV-2, HIV-1, and HCV) also depleted SPOC1 in infected cells. Our findings provide a general model for how pathogenic human viruses antagonize intrinsic SPOC1-mediated antiviral responses in their host cells. A better understanding of viral entry and early restrictive functions in host cells should provide new perspectives for developing antiviral agents and therapies. Conversely, for Ad vectors used in gene therapy, counteracting mechanisms eradicating incoming

  1. WW Geminorum: An early B-type eclipsing binary evolving into the contact phase

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Y.-G.; Dai, H.-F.; Yin, X.-G. [School of Physics and Electronic Information, Huaibei Normal University, 235000 Huaibei, Anhui Province (China); Yang, Y., E-mail: yygcn@163.com, E-mail: yangyg@chnu.edu.cn, E-mail: yangy818@yeah.net [Department of Electronic Engineering, School of Information Science Technology, East China Normal University, 200241 Shanghai (China)

    2014-11-01

    WW Gem is a B-type eclipsing binary with a period of 1.2378 days. The CCD photometry of this binary was performed in 2013 December using the 85 cm telescope at the Xinglong Stations of the National Astronomical Observatories of China. Using the updated W-D program, the photometric model was deduced from the VRI light curves. The results imply that WW Gem is a near-contact eclipsing binary whose primary component almost fills its Roche lobe. The photometric mass ratio is q {sub ph} = 0.48(± 0.05). All collected times of minimum light, including two new ones, were used for the period studies. The orbital period changes of WW Gem could be described by an upward parabola, possibly overlaid by a light-time orbit with a period of P {sub mod} = 7.41(± 0.04) yr and a semi-amplitude of A = 0.0079 days(± 0.0005 days), respectively. This kind of cyclic oscillation may be attributed to the light-travel time effect via the third body. The long-term period increases at a rate of dP/dt = +3.47(±0.04) × 10{sup –8} day yr{sup –1}, which may be explained by the conserved mass transfer from the less massive component to the more massive one. With mass transfer, the massive binary WW Gem may be evolving into a contact binary.

  2. Gender-typed behaviors, achievement, and adjustment among racially and ethnically diverse boys during early adolescence.

    Science.gov (United States)

    Santos, Carlos E; Galligan, Kathrine; Pahlke, Erin; Fabes, Richard A

    2013-01-01

    This research examined the relations between adherence to gender-typed behaviors in boys' friendships, achievement, and self-esteem. Participants were racially and ethnically diverse adolescent boys in grade 8 (Mage  = 13.05; range = 12-14). The study was completed at a public junior high school that offered both single- and mixed-gender classes. Data were collected in 2 waves, the first wave in fall of 2010 and the second in spring of 2011. At each wave, participants completed assessments of gender concepts and self-esteem. Standardized tests scores from the end of the previous academic year and the end of the year of the study were utilized. Results revealed that the boys' adherence to physical toughness behaviors in their friendships was negatively associated with math standardized test scores and self-esteem from Time I to Time II. Indirect effects analyses revealed a relation between boys' adherence to emotional stoicism behaviors in friendships and math achievement and self-esteem via boys' adherence to physical toughness behaviors. Implications of these findings and the links between masculinity, boys' friendships, performance in school, and psychological adjustment are discussed.

  3. An improved early detection method of type-2 diabetes mellitus using multiple classifier system

    KAUST Repository

    Zhu, Jia

    2015-01-01

    The specific causes of complex diseases such as Type-2 Diabetes Mellitus (T2DM) have not yet been identified. Nevertheless, many medical science researchers believe that complex diseases are caused by a combination of genetic, environmental, and lifestyle factors. Detection of such diseases becomes an issue because it is not free from false presumptions and is accompanied by unpredictable effects. Given the greatly increased amount of data gathered in medical databases, data mining has been used widely in recent years to detect and improve the diagnosis of complex diseases. However, past research showed that no single classifier can be considered optimal for all problems. Therefore, in this paper, we focus on employing multiple classifier systems to improve the accuracy of detection for complex diseases, such as T2DM. We proposed a dynamic weighted voting scheme called multiple factors weighted combination for classifiers\\' decision combination. This method considers not only the local and global accuracy but also the diversity among classifiers and localized generalization error of each classifier. We evaluated our method on two real T2DM data sets and other medical data sets. The favorable results indicated that our proposed method significantly outperforms individual classifiers and other fusion methods.

  4. Enhanced dust heating in the bulges of early-type spiral galaxies

    CERN Document Server

    Engelbracht, C W; Skibba, R A; Hinz, J L; Calzetti, D; Gordon, K D; Roussel, H; Crocker, A F; Misselt, K A; Bolatto, A D; Kennicutt, R C; Appleton, P N; Armus, L; Beirão, P; Brandl, B R; Croxall, K V; Dale, D A; Draine, B T; Dumas, G; de Paz, A Gil; Groves, B; Hao, C -N; Johnson, B D; Koda, J; Krause, O; Leroy, A K; Meidt, S E; Murphy, E J; Rahman, N; Rix, H -W; Sandstrom, K M; Sauvage, M; Schinnerer, E; Smith, J -D T; Srinivasan, S; Vigroux, L; Walter, F; Warren, B E; Wilson, C D; Wolfire, M G; Zibetti, S

    2010-01-01

    Stellar density and bar strength should affect the temperatures of the cool (T ~ 20-30 K) dust component in the inner regions of galaxies, which implies that the ratio of temperatures in the circumnuclear regions to the disk should depend on Hubble type. We investigate the differences between cool dust temperatures in the central 3 kpc and disk of 13 nearby galaxies by fitting models to measurements between 70 and 500 microns. We attempt to quantify temperature trends in nearby disk galaxies, with archival data from Spitzer/MIPS and new observations with Herschel/SPIRE, which were acquired during the first phases of the Herschel observations for the KINGFISH (key insights in nearby galaxies: a far-infrared survey with Herschel) sample. We fit single-temperature modified blackbodies to far-infrared and submillimeter measurements of the central and disk regions of galaxies to determine the temperature of the component(s) emitting at those wavelengths. We present the ratio of central-region-to-disk-temperatures ...

  5. Early X-ray emission from Type Ia supernovae originating from symbiotic progenitors or recurrent novae

    CERN Document Server

    Dimitriadis, Georgios; Vink, Jacco

    2014-01-01

    One of the key observables for determining the progenitor nature of Type Ia supernovae is provided by their immediate circumstellar medium, which according to several models should be shaped by the progenitor binary system. So far, X-ray and radio observations indicate that the surroundings are very tenuous, producing severe upper-limits on the mass loss from winds of the progenitors. In this study, we perform numerical hydro-dynamical simulations of the interaction of the SN ejecta with circumstellar structures formed by possible mass outflows from the progenitor systems and we estimate numerically the expected numerical X-ray luminosity. We consider two kinds of circumstellar structures: a) A circumstellar medium formed by the donor star's stellar wind, in case of a symbiotic binary progenitor system; b) A circumstellar medium shaped by the interaction of the slow wind of the donor star with consecutive nova outbursts for the case of a symbiotic recurrent nova progenitor system. For the hydro-simulations we...

  6. Optical Interferometry of early-type stars with PAVO@CHARA. I. Fundamental stellar properties

    CERN Document Server

    Maestro, V; Huber, D; Ireland, M J; Monnier, J D; White, T R; Kok, Y; Robertson, J G; Schaefer, G H; Brummelaar, T A Ten; Tuthill, P G

    2013-01-01

    We present interferometric observations of 7 main-sequence and 3 giant stars with spectral types from B2 to F6 using the PAVO beam combiner at the CHARA array. We have directly determined the angular diameters for these objects with an average precision of 2.3%. We have also computed bolometric fluxes using available photometry in the visible and infrared wavelengths, as well as space-based ultraviolet spectroscopy. Combined with precise \\textit{Hipparcos} parallaxes, we have derived a set of fundamental stellar properties including linear radius, luminosity and effective temperature. Fitting the latter to computed isochrone models, we have inferred masses and ages of the stars. The effective temperatures obtained are in good agreement (at a 3% level) with nearly-independent temperature estimations from spectroscopy. They validate recent sixth-order polynomial (B-V)-$T_\\mathrm{eff}$ empirical relations \\citep{Boyajian2012a}, but suggest that a more conservative third-order solution \\citep{vanBelle2009} could ...

  7. Dwarfism and early death in mice lacking C-type natriuretic peptide

    Science.gov (United States)

    Chusho, Hideki; Tamura, Naohisa; Ogawa, Yoshihiro; Yasoda, Akihiro; Suda, Michio; Miyazawa, Takashi; Nakamura, Kenji; Nakao, Kazuki; Kurihara, Tatsuya; Komatsu, Yasato; Itoh, Hiroshi; Tanaka, Kiyoshi; Saito, Yoshihiko; Katsuki, Motoya; Nakao, Kazuwa

    2001-01-01

    Longitudinal bone growth is determined by endochondral ossification that occurs as chondrocytes in the cartilaginous growth plate undergo proliferation, hypertrophy, cell death, and osteoblastic replacement. The natriuretic peptide family consists of three structurally related endogenous ligands, atrial, brain, and C-type natriuretic peptides (ANP, BNP, and CNP), and is thought to be involved in a variety of homeostatic processes. To investigate the physiological significance of CNP in vivo, we generated mice with targeted disruption of CNP (Nppc−/− mice). The Nppc−/− mice show severe dwarfism as a result of impaired endochondral ossification. They are all viable perinatally, but less than half can survive during postnatal development. The skeletal phenotypes are histologically similar to those seen in patients with achondroplasia, the most common genetic form of human dwarfism. Targeted expression of CNP in the growth plate chondrocytes can rescue the skeletal defect of Nppc−/− mice and allow their prolonged survival. This study demonstrates that CNP acts locally as a positive regulator of endochondral ossification in vivo and suggests its pathophysiological and therapeutic implication in some forms of skeletal dysplasia. PMID:11259675

  8. Early Observations and Analysis of the Type Ia SN 2014J in M82

    CERN Document Server

    Marion, G H; Hsiao, E Y; Banerjee, D P K; Valenti, S; Stritzinger, M D; Vinkó, J; Joshi, V; Venkataraman, V; Ashok, N M; Amanullah, R; Binzel, R P; Bochanski, J J; Bryngelson, G L; Burns, C R; Drozdov, D; Fieber-Beyer, S K; Graham, M L; Howell, D A; Johansson, J; Kirshner, R P; Milne, P A; Parrent, J; Silverman, J M; Vervack, R J; Wheeler, J C

    2014-01-01

    We present optical and near infrared (NIR) observations of the nearby Type Ia SN 2014J. Seventeen optical and twenty-three NIR spectra were obtained from 10 days before ($-$10d) to 10 days after (+10d) the time of maximum $B$-band brightness. The relative strengths of absorption features and their patterns of development can be compared at one day intervals throughout most of this period. Carbon is not detected in the optical spectra, but we identify CI $\\lambda$ 1.0693 in the NIR spectra. We find that MgII lines with high oscillator strengths have higher initial velocities than other MgII lines. We show that the velocity differences can be explained by differences in optical depths due to oscillator strengths. The spectra of SN 2014J show it is a normal SN Ia, but many parameters are near the boundaries between normal and high-velocity subclasses. The velocities for OI, MgII, SiII, SII, CaII and FeII suggest that SN 2014J has a layered structure with little or no mixing. That result is consistent with the de...

  9. RBE of Energetic Iron Ions for the Induction of Early and Late Chromosome Aberrations in Different Cell Types

    Science.gov (United States)

    Zhang, Ye; Yeshitla, Samrawit; Hada, Megumi; Kadhim, Munira; Wilson, Bobby; Wu, Honglu

    2014-01-01

    Numerous published studies have reported the RBE values for chromosome chromosomes induced by charged particles of different LET. The RBE for chromosome aberrations in human lymphocytes exposed ex vivo showed a similar relationship as the quality factor for cancer induction. Consequently, increased chromosome aberrations in the astronauts' white blood cells post long-duration missions are used to determine the biological doses from exposures to space radiation. The RBE value is known to be very different for different types of cancer. Previously, we reported that the RBE for initial chromosome damages was high in human lymphocytes exposed to Fe ions. After multiple cell divisions post irradiation, the RBE was significantly smaller. To test the hypothesis that the RBE values for chromosome aberrations are different between early and late damages and also different between different cell types, we exposed human lymphocytes ex vivo, and human fibroblast cells and human mammary epithelial cells in vitro to 600 MeV/u Fe ions. Post irradiation, the cells were collected at first mitosis, or cultured for multiple generations for collections of remaining or late arising chromosome aberrations. The chromosome aberrations were quantified using fluorescent in situ hybridization (FISH) with whole chromosome specific probes. This study attempts to offer an explanation for the varying RBE values for different cancer types.

  10. Early-time light curves of Type Ib/c supernovae from the SDSS-II Supernova Survey

    CERN Document Server

    Taddia, F; Leloudas, G; Stritzinger, M D; Valenti, S; Galbany, L; Kessler, R; Schneider, D P; Wheeler, J C

    2014-01-01

    We analyse the early-time optical light curves (LCs) of 20 Type Ib/c supernovae (SNe Ib/c) from the Sloan Digital Sky Survey (SDSS) SN survey II, aiming to study their properties as well as to derive their progenitor parameters. High-cadence, multi-band LCs are fitted with a functional model and the best-fit parameters are compared among the SN types. Bolometric LCs (BLCs) are constructed for the entire sample. We computed the black-body (BB) temperature (T_BB) and photospheric radius (R_ph) evolution for each SN via BB fits on the spectral energy distributions. In addition, the BLC properties are compared to model expectations. Complementing our sample with literature data, we find that SNe Ic and Ic-BL (broad-line) have shorter rise times than those of SNe Ib and IIb. \\Delta m_15 is similar among the different sub-types. SNe Ic appear brighter and bluer than SNe Ib, but this difference vanishes if we consider host galaxy extinction corrections based on colors. Our SNe have typical T_BB ~ 10000 K at peak, an...

  11. A PANCHROMATIC CATALOG OF EARLY-TYPE GALAXIES AT INTERMEDIATE REDSHIFT IN THE HUBBLE SPACE TELESCOPE WIDE FIELD CAMERA 3 EARLY RELEASE SCIENCE FIELD

    Energy Technology Data Exchange (ETDEWEB)

    Rutkowski, M. J.; Cohen, S. H.; Windhorst, R. A. [School of Earth and Space Exploration, Arizona State University, Tempe, AZ 85287-1404 (United States); Kaviraj, S.; Crockett, R. M.; Silk, J. [Department of Physics, University of Oxford, Denys Wilkinson Building, Keble Road, Oxford OX1 3RH (United Kingdom); O' Connell, R. W. [Department of Astronomy, University of Virginia, P.O. Box 3818, Charlottesville, VA 22903 (United States); Hathi, N. P.; McCarthy, P. J. [Observatories of the Carnegie Institute of Washington, Pasadena, CA 91101 (United States); Ryan, R. E. Jr.; Koekemoer, A.; Bond, H. E. [Space Telescope Science Institute, Baltimore, MD 21218 (United States); Yan, H. [Center for Cosmology and Astroparticle Physics, Ohio State University, Columbus, OH 43210 (United States); Kimble, R. A. [NASA-Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Balick, B. [Department of Astronomy, University of Washington, Seattle, WA 98195-1580 (United States); Calzetti, D. [Department of Astronomy, University of Massachusetts, Amherst, MA 01003 (United States); Disney, M. J. [School of Physics and Astronomy, Cardiff University, Cardiff CF24 3AA (United Kingdom); Dopita, M. A. [Research School of Physics and Astronomy, The Australian National University, ACT 2611 (Australia); Frogel, J. A. [Astronomy Department, King Abdulaziz University, P.O. Box 80203, Jeddah (Saudi Arabia); Hall, D. N. B. [Institute for Astronomy, University of Hawaii, Honolulu, HI 96822 (United States); and others

    2012-03-01

    In the first of a series of forthcoming publications, we present a panchromatic catalog of 102 visually selected early-type galaxies (ETGs) from observations in the Early Release Science (ERS) program with the Wide Field Camera 3 (WFC3) on the Hubble Space Telescope (HST) of the Great Observatories Origins Deep Survey-South (GOODS-S) field. Our ETGs span a large redshift range, 0.35 {approx}< z {approx}< 1.5, with each redshift spectroscopically confirmed by previous published surveys of the ERS field. We combine our measured WFC3 ERS and Advanced Camera for Surveys (ACS) GOODS-S photometry to gain continuous sensitivity from the rest-frame far-UV to near-IR emission for each ETG. The superior spatial resolution of the HST over this panchromatic baseline allows us to classify the ETGs by their small-scale internal structures, as well as their local environment. By fitting stellar population spectral templates to the broadband photometry of the ETGs, we determine that the average masses of the ETGs are comparable to the characteristic stellar mass of massive galaxies, 10{sup 11} < M{sub *}[M{sub Sun }]<10{sup 12}. By transforming the observed photometry into the Galaxy Evolution Explorer FUV and NUV, Johnson V, and Sloan Digital Sky Survey g' and r' bandpasses we identify a noteworthy diversity in the rest-frame UV-optical colors and find the mean rest-frame (FUV-V) = 3.5 and (NUV-V) = 3.3, with 1{sigma} standard deviations {approx_equal}1.0. The blue rest-frame UV-optical colors observed for most of the ETGs are evidence for star formation during the preceding gigayear, but no systems exhibit UV-optical photometry consistent with major recent ({approx}<50 Myr) starbursts. Future publications which address the diversity of stellar populations likely to be present in these ETGs, and the potential mechanisms by which recent star formation episodes are activated, are discussed.

  12. Glycemic control in youth with type 2 diabetes declines as early as two years after diagnosis.

    Science.gov (United States)

    Levitt Katz, Lorraine E; Magge, Sheela Natesh; Hernandez, Marcia L; Murphy, Kathryn M; McKnight, Heather M; Lipman, Terri

    2011-01-01

    To determine the course of glycemic decline in a pediatric cohort with type 2 diabetes mellitus (T2DM) by defining longitudinal changes in hemoglobin A1c (HbA1c) and insulin requirement. We also followed markers of insulin reserve (fasting C-peptide and IGFBP-1) over time. Participants included two groups: (1) T2DM Nonacidotic (NA) (n = 46); and (2) T2DM diabetic ketoacidosis (n = 13). HbA1c, insulin dose, and fasting C-peptide and IGFBP-1 were obtained at baseline and every 6 months for 4 years. At baseline, Mann Whitney tests demonstrated that the diabetic ketoacidosis group had higher HbA1c (P = .002), required more insulin (P = .036), and had lower C-peptide (P = .003) than the NA group. Baseline insulin dose (Spearman r = -0.424, P = .009) and baseline IGFBP-1 (Spearman r = -0.349, P = .046) correlated negatively with C-peptide. Over time, HbA1c, insulin dose, and C-peptide changed significantly in a complex manner, with group differences. HbA1c reached a nadir at 6 to 12 months and began to rise after 1.5 years. Insulin requirements reached a nadir at 1 year and began to rise after 2 years. Unlike adults, children with T2DM require increasing insulin doses over a 4-year period, and diabetic ketoacidosis at diagnosis predicts greater β-cell decline over time. Copyright © 2011 Mosby, Inc. All rights reserved.

  13. Tracking the cognitive, social and neuroanatomical profile in early neurodegeneration: Type III Cockayne syndrome

    Directory of Open Access Journals (Sweden)

    Sandra eBaez

    2013-11-01

    Full Text Available Cockayne syndrome (CS is an autosomal recessive disease associated with premature aging, progressive multiorgan degeneration and nervous system abnormalities including cerebral and cerebellar atrophy, brain calcifications and white matter abnormalities. Although several clinical descriptions of CS patients have reported developmental delay and cognitive impairment with relative preservation of social skills, no previous studies have carried out a comprehensive neuropsychological and social cognition assessment. Furthermore, no previous research in individuals with CS has examined the relationship between brain atrophy and performance on neuropsychological and social cognition tests. This study describes the case of an atypical late-onset type III CS patient who exceeds the mean life expectancy of individuals with this pathology. The patient and a group of healthy controls underwent a comprehensive assessment that included multiple neuropsychological and social cognition (emotion recognition, theory of mind and empathy tasks. In addition, we compared the pattern of atrophy in the patient to controls and to its concordance with ERCC8 gene expression in a healthy brain. The results showed memory, language and executive deficits that contrast with the relative preservation of social cognition skills. The cognitive profile of the patient was consistent with his pattern of global cerebral and cerebellar loss of gray matter volume (frontal structures, bilateral cerebellum, basal ganglia, temporal lobe, and occipito-temporal/occipito-parietal regions, which in turn was anatomically consistent with the ERCC8 gene expression level in a healthy donor’s brain. The study of exceptional cases, such as the one described here, is fundamental to elucidating the processes that affect the brain in premature aging diseases, and such studies provide an important source of information for understanding the problems associated with normal and pathological aging.

  14. Tracking the Cognitive, Social, and Neuroanatomical Profile in Early Neurodegeneration: Type III Cockayne Syndrome.

    Science.gov (United States)

    Baez, Sandra; Couto, Blas; Herrera, Eduar; Bocanegra, Yamile; Trujillo-Orrego, Natalia; Madrigal-Zapata, Lucia; Cardona, Juan Felipe; Manes, Facundo; Ibanez, Agustin; Villegas, Andres

    2013-01-01

    Cockayne syndrome (CS) is an autosomal recessive disease associated with premature aging, progressive multiorgan degeneration, and nervous system abnormalities including cerebral and cerebellar atrophy, brain calcifications, and white matter abnormalities. Although several clinical descriptions of CS patients have reported developmental delay and cognitive impairment with relative preservation of social skills, no previous studies have carried out a comprehensive neuropsychological and social cognition assessment. Furthermore, no previous research in individuals with CS has examined the relationship between brain atrophy and performance on neuropsychological and social cognition tests. This study describes the case of an atypical late-onset type III CS patient who exceeds the mean life expectancy of individuals with this pathology. The patient and a group of healthy controls underwent a comprehensive assessment that included multiple neuropsychological and social cognition (emotion recognition, theory of mind, and empathy) tasks. In addition, we compared the pattern of atrophy in the patient to controls and to its concordance with ERCC8 gene expression in a healthy brain. The results showed memory, language, and executive deficits that contrast with the relative preservation of social cognition skills. The cognitive profile of the patient was consistent with his pattern of global cerebral and cerebellar loss of gray matter volume (frontal structures, bilateral cerebellum, basal ganglia, temporal lobe, and occipito-temporal/occipito-parietal regions), which in turn was anatomically consistent with the ERCC8 gene expression level in a healthy donor's brain. The study of exceptional cases, such as the one described here, is fundamental to elucidating the processes that affect the brain in premature aging diseases, and such studies provide an important source of information for understanding the problems associated with normal and pathological aging.

  15. Monitoring early fusion dynamics of human immunodeficiency virus type 1 at single-molecule resolution.

    Science.gov (United States)

    Dobrowsky, Terrence M; Zhou, Yan; Sun, Sean X; Siliciano, Robert F; Wirtz, Denis

    2008-07-01

    The fusion of human immunodeficiency virus type 1 (HIV-1) to host cells is a dynamic process governed by the interaction between glycoproteins on the viral envelope and the major receptor, CD4, and coreceptor on the surface of the cell. How these receptors organize at the virion-cell interface to promote a fusion-competent site is not well understood. Using single-molecule force spectroscopy, we map the tensile strengths, lifetimes, and energy barriers of individual intermolecular bonds between CCR5-tropic HIV-1 gp120 and its receptors CD4 and CCR5 or CXCR4 as a function of the interaction time with the cell. According to the Bell model, at short times of contact between cell and virion, the gp120-CD4 bond is able to withstand forces up to 35 pN and has an initial lifetime of 0.27 s and an intermolecular length of interaction of 0.34 nm. The initial bond also has an energy barrier of 6.7 k(B)T (where k(B) is Boltzmann's constant and T is absolute temperature). However, within 0.3 s, individual gp120-CD4 bonds undergo rapid destabilization accompanied by a shortened lifetime and a lowered tensile strength. This destabilization is significantly enhanced by the coreceptor CCR5, not by CXCR4 or fusion inhibitors, which suggests that it is directly related to a conformational change in the gp120-CD4 bond. These measurements highlight the instability and low tensile strength of gp120-receptor bonds, uncover a synergistic role for CCR5 in the progression of the gp120-CD4 bond, and suggest that the cell-virus adhesion complex is functionally arranged about a long-lived gp120-coreceptor bond.

  16. EARLY OBSERVATIONS AND ANALYSIS OF THE TYPE Ia SN 2014J IN M82

    Energy Technology Data Exchange (ETDEWEB)

    Marion, G. H.; Vinkó, J. [University of Texas at Austin, 1 University Station C1400, Austin, TX 78712-0259 (United States); Sand, D. J. [Physics Department, Texas Tech University, Lubbock, TX 79409 (United States); Hsiao, E. Y. [Carnegie Observatories, Las Campanas Observatory, Colina El Pino, Casilla 601 (Chile); Banerjee, D. P. K.; Joshi, V.; Venkataraman, V.; Ashok, N. M. [Astronomy and Astrophysics Division, Physical Research Laboratory, Navrangapura, Ahmedabad - 380009, Gujarat (India); Valenti, S.; Howell, D. A. [Las Cumbres Observatory Global Telescope Network, 6740 Cortona Drive, Suite 102, Santa Barbara, CA 93117 (United States); Stritzinger, M. D. [Department of Physics and Astronomy, Aarhus University, Ny Munkegade 120, DK-8000 Aarhus C (Denmark); Amanullah, R.; Johansson, J. [The Oskar Klein Centre, Physics Department, Stockholm University, Albanova University Center, SE 106 91 Stockholm (Sweden); Binzel, R. P. [Department of Earth, Atmospheric, and Planetary Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139 (United States); Bochanski, J. J. [Haverford College, 370 Lancaster Avenue, Haverford, PA 19041 (United States); Bryngelson, G. L. [Department of Physics and Astronomy, Francis Marion University, 4822 East Palmetto Street, Florence, SC 29506 (United States); Burns, C. R. [Observatories of the Carnegie Institution for Science, 813 Santa Barbara Street, Pasadena, CA 91101 (United States); Drozdov, D. [Department of Physics and Astronomy, Clemson University, 8304 University Station, Clemson, SC 29634 (United States); Fieber-Beyer, S. K. [Department of Space Studies, University of North Dakota, University Stop 9008, ND 58202 (United States); Graham, M. L., E-mail: hman@astro.as.utexas.edu [Astronomy Department, University of California at Berkeley, Berkeley, CA 94720 (United States); and others

    2015-01-01

    We present optical and near infrared (NIR) observations of the nearby Type Ia SN 2014J. Seventeen optical and 23 NIR spectra were obtained from 10 days before (–10d) to 10 days after (+10d) the time of maximum B-band brightness. The relative strengths of absorption features and their patterns of development can be compared at one day intervals throughout most of this period. Carbon is not detected in the optical spectra, but we identify C I λ1.0693 in the NIR spectra. Mg II lines with high oscillator strengths have higher initial velocities than other Mg II lines. We show that the velocity differences can be explained by differences in optical depths due to oscillator strengths. The spectra of SN 2014J show that it is a normal SN Ia, but many parameters are near the boundaries between normal and high-velocity subclasses. The velocities for O I, Mg II, Si II, S II, Ca II, and Fe II suggest that SN 2014J has a layered structure with little or no mixing. That result is consistent with the delayed detonation explosion models. We also report photometric observations, obtained from –10d to +29d, in the UBVRIJH and K{sub s} bands. The template fitting package SNooPy is used to interpret the light curves and to derive photometric parameters. Using R{sub V} = 1.46, which is consistent with previous studies, SNooPy finds that A{sub V} = 1.80 for E(B – V){sub host} = 1.23 ± 0.06 mag. The maximum B-band brightness of –19.19 ± 0.10 mag was reached on February 1.74 UT ± 0.13 days and the supernova has a decline parameter, Δm {sub 15}, of 1.12 ± 0.02 mag.

  17. Human heart-type fatty acid-binding protein as an early diagnostic marker of doxorubicin cardiac toxicity

    Directory of Open Access Journals (Sweden)

    Ashraf H. ElGhandour

    2009-04-01

    Full Text Available Progressive cardiotoxicity following treatment with doxorubicin-based chemotherapy in patients with non-Hodgkin’s lymphoma (NHL may lead to late onset cardiomyopathy. So, early prediction of toxicity can lead to prevention of heart failure in these patients. The aim of this work was to investigate the role of H-FABP as an early diagnostic marker of anthracycline-induced cardiac toxicity together with brain natriuretic peptide (BNP as an indication of ventricular dysfunction in such patients. Our study was conducted on 40 NHL patients who received 6 cycles of a doxorubicin containing chemotherapy protocol (CHOP, not exceeding the total allowed dose of doxorubicin (500 mg/m2. Ten healthy controls were included in our study. Human heart-type fatty acid binding protein (H-FABP was assessed 24 hours after the first cycle of CHOP. Plasma levels of BNP were estimated both before starting chemotherapy and after the last cycle of CHOP. Resting echocardiography was also performed before and at the end of chemotherapy cycles. The ejection fraction (EF of 8 of our patients decreased below 50% at the end of the sixth cycle. Elevated levels of both H-FABP and BNP were found in all patients wth EF below 50% and both markers showed a positive correlation with each other. We concluded that H-FABP may serve as a reliable early marker for prediction of cardiomyopathy induced by doxorubicin. Thus, in patients with elevated H-FABP, alternative treatment modalities with no cardiac toxicity may be considered in order to prevent subsequent heart failure in these patients.

  18. Dysmorphic choroid plexuses and hydrocephalus associated with increased nuchal translucency: early ultrasound markers of de novo thanatophoric dysplasia type II with cloverleaf skull (Kleeblattschaedel).

    Science.gov (United States)

    Tonni, Gabriele; Palmisano, Marcella; Ginocchi, Vladimiro; Ventura, Alessandro; Baldi, Maurizia; Baffico, Ave Maria

    2014-11-01

    Prenatal diagnosis of thanatophoric dysplasia (TD) type II presenting in the first trimester with increased nuchal translucency (NT) and cloverleaf skull (Kleeblattschaedel) have been scantly reported in the medical record. Abnormal choroid plexus has been seen in association with fetal anomalies. Here we described a case of increased NT associated with indented choroid plexuses, early onset hydrocephalus and cloverleaf skull in a fetus subsequently diagnosed at early second trimester to carry a de novo mutation encoding for TD type II. The findings of dysmorphic choroid plexus, early onset hydrocephalus and cloverleaf skull at first trimester scan may be early, useful ultrasound markers of TD type II. Molecular analysis to control for possible overlapping syndromes were performed and resulted negative. Postmortem X-ray and 3D-CT scan confirmed the cloverleaf skull, narrow thorax, straight femur with rhizomelic shortening of the limbs and the presence of a communicating hydrocephalus.

  19. AN EMPIRICAL CONNECTION BETWEEN THE ULTRAVIOLET COLOR OF EARLY-TYPE GALAXIES AND THE STELLAR INITIAL MASS FUNCTION

    Energy Technology Data Exchange (ETDEWEB)

    Zaritsky, Dennis [Steward Observatory, University of Arizona, 933 North Cherry Avenue, Tucson, AZ 85721 (United States); Gil de Paz, Armando; Bouquin, Alexandre Y. K., E-mail: dennis.zaritsky@gmail.com [Departamento de Astrofísica y CC. de la Atmósfera, Facultad de CC. Físicas, Universidad Complutense de Madrid, Avda. de la Complutense s/n, Madrid E-28040 (Spain)

    2014-01-01

    Using new UV magnitudes for a sample of early-type galaxies (ETGs) with published stellar mass-to-light ratios, Y{sub *}, we find a correlation between UV color and Y{sub *} that is tighter than those previously identified between Y{sub *} and either the central stellar velocity dispersion, metallicity, or alpha enhancement. The sense of the correlation is that galaxies with larger Y{sub *} are bluer in the UV. We conjecture that differences in the lower mass end of the stellar initial mass function (IMF) are related to the nature of the extreme horizontal branch populations that are generally responsible for the UV flux in ETGs. If so, then UV color can be used to identify ETGs with particular IMF properties and to estimate Y{sub *}.

  20. VizieR Online Data Catalog: UV to IR fluxes of 221 early-type galaxies (Amblard+, 2014)

    Science.gov (United States)

    Amblard, A.; Riguccini, L.; Temi, P.; Im, S.; Fanelli, M.; Serra, P.

    2016-06-01

    We base our work on a sample of 225 early-type galaxies from Temi et al. 2009 (cat. J/ApJ/707/890). We present a large fraction of their SED from the ultraviolet to the far-infrared (Tables 1-4). We concentrate primarily on six instruments which span these wavelengths and have extensive sky coverage: Galaxy Evolution Explorer (GALEX; see Bianchi et al. 2001, cat. II/312) for the UV part, SDSS (see SDSS-DR9 in cat. V/139) for the optical, Two Micron All Sky Survey (2MASS; Cutri et al. 2003, cat. II/246) and IRAC-Spitzer for the NIR and MIR, and MIPS-Spitzer and IRAS for the mid and FIR. We also use public data from Herschel-SPIRE when available (see Table4). (5 data files).