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Sample records for dorsal del pie

  1. Tratamiento del pie equino

    OpenAIRE

    Robles, Fernanda

    2012-01-01

    El pie equino varo es una patología frecuente en los pacientes con Encefalopatía crónica no evolutiva (ECNE).Se observó que existe una mayor frecuencia en el sexo masculino. Se realizó un estudio descriptivo, comparativo y secundario, durante el periodo de septiembre del 2006 a septiembre del 2011, con un total de 125 pacientes con Ecne, de los cuales se encontraron 101 con pie equino varo congénito. Objetivo: observar los resultados obtenidos en la rehabilitación del pie equino, en niños de ...

  2. El pie del adulto mayor

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    Parodi García, José Francisco

    2005-01-01

    Acta Médica Peruana es una publicación del Colegio Médico del Perú El estudio del pie y sus patologías es un capítulo muy importante de la Geriatría. Las patologías del pie no escapan las características comunes de muchos síndromes geriátricos como son el ser asumidos como "normales para la edad", ser poco valorados, menospreciados, no tratados, con gran impacto sobre la salud en general y la calidad de vida.

  3. Tratamiento Actual del Pie Zambo

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    Salom Taverner, M.; Mínguez Rey, María Fe

    2015-01-01

    El pie zambo es una deformidad congénita en la que el pie presenta una deformidad en equino, varo de retropié, aductus del antepié y cavo. Su tratamiento ha variado con el tiempo. Clásicamente se trataba mediante distintas técnicas quirúrgicas que permitían corregir todas las deformidades pero que se acompañaban de frecuentes complicaciones a corto y largo plazo. Actualmente el tratamiento más extendido de esta deformidad es el tratamiento conservador mediante la técnica de Ponset...

  4. Nuestro concepto actual del pie valgo

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    Dorca Coll, Adelina; Cespedes Cespedes, Tomás; Concustell Gonfaus, Josep; Sacristán Valero, Sergi; Dorca Coll, Ma. Rosa

    1996-01-01

    Los autores hacen una revisión de los conceptos y etiologías que se han descrito del pie valgo. Incluyen una definición personal sobre el concepto funcional del pie valgo, definen por primera vez la marcha que cursa con estrés en valgo y presentan una descripción del comportamiento biomecánico de los diferentes pies valgos. Esta diferenciación será de gran utilidad para la posterior aplicación del tratamiento ortopodológico adecuado. Es de resaltar las imágenes que se presentan obtenidas de c...

  5. El pie del diabético

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    Parra Myriam

    1990-12-01

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    Existen complicaciones neurovasculares periféricas en el paciente diabético que de no prevenirse o tratarse precozmente pueden conducir a la formación de lesiones graves e irreversibles en el pie. Los grados de lesión pueden evolucionar desde la presencia de factores de riesgo hasta la formación de gangrena local o generalizada conllevando a la amputación del pie. La participación del paciente y la familia con relación a los cuidados podológicos, cumplimiento en el  tratamiento dietético, farmacológico, de ejercicio e identificación de riesgos son definitivos; estos aspectos requieren de la orientación e intervención del profesional de enfermería en el manejo de cada grado de lesión basándose en la identificación de diagnósticos reales y/o potenciales prioritarios.

  6. Enfoque integral del paciente con pie diabético

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    Galia Fonseca Portilla

    1996-04-01

    Full Text Available Debe tenerse en cuenta que el diagnóstico de Diabetes Mellitus supone un cambio radical en las costumbres del paciente y que alcanzarlo puede requerir largo tiempo, por esto es necesario que los pacientes asistan a control cada dos o tres meses ye n cada visita insistirle en la importancia de curaciones. Si se continúa apoyando sobre la úlcera, se siguen exprimiendo, como esponja, las bacterias. Para el manejo del pie diabético se distinguen: prevención primaria (detección precoz del pie en riesgo, prevención secundaria (cuidado adecuado de las úlceras grado 1, 2 por el equipo interdisciplinario y prevención terciaria (a nivel hospitalario, para evitar la amputación de los pies con úlceras grado 3-5.

  7. Clínica del pie valgo

    OpenAIRE

    Marcelino Reyes, Jesús

    1998-01-01

    Genericamente reconocemos al pie valgo, por las características siguientes: - desviación de la linea de Helbing ( retropié) - aplanamiento de la bóveda longitudinal interna - pronación de antepié. - aspecto de pié plano. Pero no podemos contentarnos con estas cuatro reglas,y por lo tanto hemos de pormenorizar y clasificar en función de los diferentes elementos que intervienen en la morfogenética de pié. Con lo cual también tendremos una visión mas amplia a la hora de poder aplicar un tratamie...

  8. Consideraciones anatómicas y funcionales en la patología del quinto radio del pie

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    Gallart Ortega, José; Lahoz Gimeno, Manuel

    2013-01-01

    OBJETIVO: Se analiza si las diferentes alteraciones morfológicas y funcionales del pie se asocian estadísticamente a las diferentes desviaciones del quinto radio en el plano transverso y/o sagital como posible causa o agravantes de ésta. A su vez se describen las diferentes patologías quirúrgicas en quinto radio del pie y se evalúa el resultado goniométrico postquirúrgico de las diferentes técnicas quirúrgicas empleadas. MATERIAL MÉTODOS: En una muestra consecutiva de 121 pies intervenidos qu...

  9. Valoración de los resultados del tratamiento quirúrgico del pie plano estático

    OpenAIRE

    Paz Jiménez, José; Amigo Fernandez, A.; Romo Contreras, I.

    1989-01-01

    La deformidad fundamental del pie plano es el valgo de talón. Existe siempre un movimiento helicoidal en pronación del retropic y supinación del antepic. En este trabajo se hace una revisión de los pacientes tratados en nuestro Servicio a lo largo de diez años, que han sido sometidos a intervención quirúrgica, mayoritariamente artrodesis. - El fotopodograma constituye un excelente método para controlar la evolución de un pie plano. El pie plano por astrágalo vertical es irreductible des...

  10. Tratamiento del pie diabético en pacientes ancianos con Heberprot-P

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    José Luís Solís Licea

    2015-12-01

    Full Text Available El pie diabético constituye la complicación crónica de mayor morbimortalidad de la diabetes mellitus, significando un problema de salud internacional, del cual no escapa nuestro país y nuestro sistema de salud. Se realizó un estudio de tipo clínico observacional y descriptivo, con el objetivo de evaluar el resultado del tratamiento con Heberprot-P en pacientes con úlceras del pie diabético, en ancianos ingresados en el servicio de Angiología del Hospital General Docente “Dr. Ernesto Guevara de la Serna”, del municipio de Las Tunas, provincia de Las Tunas, en el período comprendido entre el 1ro de enero de 2010 al 31 de diciembre de 2011. Se estudiaron los pacientes según las variables de edad, localización de la lesión, resultado del tratamiento según la clasificación de Wagner y reacciones adversas presentadas. Con este estudio se pretende poner en manos del personal de la salud un material de consulta, que permita evaluar el tratamiento con Heberprot-P del pie diabético en el anciano.

  11. Alteraciones biomecánicas del antepie en el pie zambo y su tratamiento

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    Oller Asensio, Antonio; Prats Climent, Baldiri

    1991-01-01

    Definición y recuerdo anátomo-fisio-patológico del pie zambo y de las alteraciones funcionales más frecuentes que se encuentran asociadas a esta patología. Se define la metodología básica de exploración física del paciente y estudio radiológico con la determinación de las tangentes tibio-calcáneas. Desarrollo de los tratamientos generales, ortopodológicos, fisioterapéuticos y quirúrgicos. Presentación de tres casos clínicos afectos de alteraciones biomecánicas por pie zambo con su tratamiento...

  12. Factores asociados al pie diabético en pacientes ambulatorios. Centro de Diabetes Cardiovascular del Caribe. Barranquilla (Colombia

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    Mildred Rosales Amarís

    2012-01-01

    respectivamente, la neuropatía (OR = 10.14; p = 0.00 y la deformidad de los pies (OR = 10.02; p = 0.00 se asociaron significativamente al pie diabético. Se encontró como factor protector el autocuidado (OR = 0.21; p = 0.00000 y la educación relacionada con el control de factores de riesgo para la diabetes (OR = 0.32; p = 0.00007. Conclusión: La macroangiopatía, la microangiopatía, la neuropatía y la deformidad en los pies se comportaron como factores asociados a la presencia del pie diabético. El autocuidado contribuyó a la prevención del mismo.

  13. Enfermedad de mano, pie y boca en un hospital del Callao, 2016

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    Milton José Max Rodríguez-Zúñiga

    Full Text Available La enfermedad de mano, pie y boca (EMPB es una enfermedad exantemática viral, causada principalmente por Coxsackie A16, con una sintomatología típica consistente en fiebre; exantema pápulo-vesicular en manos, pies y genitales; y un enantema ulceroso en boca. En el verano del 2016 se presentó una diversidad de casos en un hospital del Callao en niños y adultos, con una sintomatología compatible con EMPB; el diagnóstico fue clínico, se aplicó terapia de soporte con resolución final de síntomas. En la última década se han presentado reportes en algunos países con una afectación atípica causada por el Coxsackie A6, produciendo lesiones más extensas y en adultos. Sin embargo, el diagnóstico sigue siendo clínico, solo necesitando confirmación virológica en casos atípicos o cuando el diagnóstico no es claro. La importancia de este reporte radica en describir los casos del Callao ocurridos en el verano del 2016, para servir de apoyo a los profesionales de la salud en el diagnóstico y manejo de pacientes con similar sintomatología.

  14. Valoración del pie plano en personas adultas con síndrome de Down y de su afectación en la vida diaria

    OpenAIRE

    Stafford, Frances

    2017-01-01

    Se realizó un estudio en 50 adultos con síndrome de Down, entre 18 y 40 años para analizar la incidencia e influencia del pie plano sobre el funcionamiento de la vida diaria. La incidencia fue del 70%, con grados diversos de pie plano. Hubo dolor en 4 personas, si bien era debido a otros problemas y no achacable al pie plano. En ningún caso la presencia de pie plano afectó al funcionamiento de la vida ordinaria.

  15. Pie en espejo

    OpenAIRE

    Delgado Quiñones, Alberto; Pancorbo Sandoval, Enrique; Diaz Prieto, Giraldo; Martín Tirado, Juan Carlos; Hernández Varela, Duniesky; Cruz Alard, Ronald

    2014-01-01

    Paciente masculino de 79 años de edad, el cual presenta en el miembro inferior izquierdo a nivel del pie una malformación congénita que corresponde a un pie en espejo, representado por 9 artejos, articulados en 8 metatarsianos, pie zambo, seudoartrosis alta de la tibia y luxación congénita alta del peroné. Es inusual encontrar esta deformidad en el momento actual. Here is a 79 years-old patient who had in his left foot a congenital malformation called mirror foot, which is represented by 9...

  16. Acciones educativas de prevención del pie diabético Educational actions to prevent diabetic foot complications

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    Pedro Vejerano García

    2009-08-01

    Full Text Available La Diabetes Mellitus y sus complicaciones son causas de hospitalización, invalidez y afectación económica. Este trabajo hace referencia a la experiencia camagüeyana en prevención, seguimiento y control del pie diabético. Dicha experiencia demostró que la pobre educación para prevenir las complicaciones del pie diabético, se convierte en un factor de riesgo sociocultural modificable. Una consulta de mayor alcance como la Clínica del Pie Diabético, pone al territorio en condiciones ventajosas para atender la transición epidemiológica de la diabetes y sus complicaciones.Diabetes Mellitus and its complications are causes of hospitalization, disability, and financial problems. This paper deals with the experience in prevention, monitoring, and control of diabetic foot in the province of Camagüey. This experience proved that a poor education in the prevention of diabetic foot complications is a modifiable sociocultural risk factor. As an example of more comprehensive consultation, the Diabetic Foot Clinic has benefitted the territory in the assistance of Diabetes Mellitus and its complications.

  17. Prevención de úlceras en el pie del paciente diabético

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    Análida Pinilla Roa

    2000-01-01

    Full Text Available La Diabetes Mellitus tipo dos (1 es una de las enfermedades metabólicas más comunes dentro de la población adulta (mayor de 30 años, da lugar a múltiples complicaciones como insuficiencia renal, enfermedades cardiovasculares, ceguera, neuropatía periférica y amputaciones de los miembros inferiores. Vale la pena destacar el profundo impacto de la diabetes en los pies debido a la gran morbilidad y mortalidad que puede causar. Se sabe que los problemas en los pies de los diabéticos son el resultado de varios factores como son la neuropatía periférica, la vasculopatía, los trastornos de la inmunidad  y los traumatismos entre otros. Cada uno de estos factores contribuye a la formación de úlceras que no sanan fácilmente y en general se infectan causando un proceso séptico que requiere el tratamiento radical de la amputación. El objetivo de este artículo es concientizar al personal de salud sobre  la necesidad de la prevención de las úlceras en los pies de los pacientes diabéticos, mediante la educación para permitir una detección temprana y un tratamiento oportuno, disminuir la tasa de úlceras y por ende de amputaciones de los miembros inferiores. La educación al paciente y al personal de salud debe incluir: el reconocimiento de signos tempranos de ulceración en las áreas de mayor presión de los pies mediante un adecuado autoexamen diario, la asesoría para el uso de calzado protector, adecuados hábitos de aseo y corte de uñas, así como medidas preventivas para evitar el trauma.

  18. Uso del método de Ilizarov en pie bot pediátrico. [Use of the Ilizarov method in pediatric clubfoot

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    Silvana Fiscina

    2013-05-01

    Full Text Available Introducción El objetivo de tratamiento del pie Bot está enfocado en lograr un pie plantígrado, indoloro y  que permita el uso del calzado habitual. El objetivo del trabajo fue medir la incidencia de recidiva luego de obtenida la corrección de la deformidad en pacientes con pie bot tratados con tutor de Ilizarov, y  analizar los factores pronósticos asociados. Material y Método Cohorte retrospectiva de factores pronóstico. Se trató con este método a 48 pacientes (70 pies desde 1988. Se excluyeron los pacientes con falta de corrección de la deformidad en el momento de retirar el tutor (deformidad residual o corrección incompleta. La variable de estudio fue la recidiva. Resultados El 77% de los 70 pies eran idiopáticos. Solo 18 pies no habían sido tratados. Todos eran pacien- tes pediátricos. El promedio de edad en el momento de la cirugía era de 7,9 años. Se incluyeron tres grupos de pacientes: tratados con Ilizarov solo (40,2%, en combi- nación con cirugía de partes blandas (38,5% y asociado con osteotomías (21,3%. El seguimiento promedio posoperatorio fue de 10,6 años (de 5,5 a 22. En el 71% de los pies, los resultados fueron pobres, la deformidad recidivó en un promedio de 38 meses, y fueron necesarias cirugías complementarias para lograr un pie plantígrado. Conclusión Presentamos una importante casuística con seguimiento alejado de pie bot recidivado o inveterado, con una alta recidiva de la deformidad (71%. No encontramos diferencias estadísticamente significativas entre los subgrupos estudiados (edad, diagnóstico, trata- mientos previos y procedimientos asociados. Actualmente no consideramos a esta técnica de primera elección, pues nuestros resultados fueron poco alentadores.

  19. Pie de madura

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    Julio E. Torres Reyes

    2014-08-01

    Full Text Available En el Hospital provincial “Antonio Agosthino Neto” de la ciudad de NDalatando, Kwanza Norte, Republica de Angola, se recibe una paciente femenina de la raza negra de 20 años de edad, con antecedentes de trabajar en el campo, laborando habitualmente descalza. Desde hace dos años, después de haberse hecho una herida con una espina de acacia, presentaba lesiones en la región del tarso y metatarso del pie derecho. Las lesiones nodulares que abarcaban la planta y dorso del pie presentaban color rojo amarillento y supuraban constantemente, con aumento de partes blandas. Se le indicaron análisis complementarios y estudios imagenológicos. Después de obtener los resultados micológicos, bacteriológicos e imagenológicos y debido a las lesiones óseas y en partes blandas que presentaba la paciente, se decide la amputación quirúrgica del pie

  20. Cuidados de enfermería en las úlceras del pie diabético. Reunión y puesta al día

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    Rincón Martín, Marina

    2016-01-01

    Entre las numerosas repercusiones de la diabetes mellitus a nivel sistémico, se pueden señalar la neuropatía, la angiopatía periférica y el aumento de la susceptibilidad para sufrir infecciones como las principales causas de la aparición de úlceras del denominado “pie diabético”, cuya incidencia en estos pacientes se estima alrededor del 15%. Debido a la magnitud de este problema, a su relación con un mayor riesgo para sufrir amputaciones, y a que en los últimos años ha aumentado el número...

  1. Enfermería: Prevención y Cuidados del Pie Diabético Revisión Bibliográfica

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    Sevillano Gamarra, Laura

    2017-01-01

    La diabetes mellitus es una de las enfermedades crónicas más prevalentes e incidentes en el mundo. Una de sus complicaciones más vigentes y que más costos socio-sanitarios acarrea, es el pie diabético que afecta al 15-25% de los pacientes diabéticos; siendo la primera causa de hospitalización, la amputación no traumática del miembro inferior. El objetivo de este trabajo es identificar los factores de riesgo relacionados con las complicaciones de la diabetes mellitus y conocer la función ed...

  2. Pie plano-valgo adquirido

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    Albiol Ferrer, Josep Maria; Giralt de Veciana, Enrique; Marugán de los Bueis, Montse; Novel Martí, Virginia; Ogalla, José Manuel; Zalacain, Antonio

    1990-01-01

    Es la patología del pie que tiene mayor incidencia durante la infancia. Su recuperación eficaz, además de precisar un largo período de tratamiento, requiere un diagnóstico precoz. Durante la lactancia, a partir de los tres meses, y después, durante la infancia, hasta los tres años aproximadamente, una gruesa y blanda capa de panlculo adiposo determina una configuración que rellena la bóveda y ofrece una falsa imagen de pie plano.

  3. El pie diabético

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    Cespedes Cespedes, Tomás; Cuevas Gómez, Rafael; Dorca Coll, Adelina; Sacristán Valero, Sergi

    1991-01-01

    El pie diabético está considerado como un pie de alto riesgo, está demostrado que si aplicáramos una adecuada y correcta educación sanitaria a todos los profesionales de la salud y al propio paciente, se podrían evitar en la mayoría de los casos las tan temidas amputaciones. En el presente trabajo hacemos referencia de las características más importantes de la diabetes, pie diabético y a la actuación profesional del podólogo frente a estos pacientes.

  4. Culturas marítimas y relaciones de poder. La trayectoria del marisqueo a pie en las Rías Bajas gallegas

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    Broullón Acuña, Esmeralda

    2010-12-01

    Full Text Available The following article addresses a female labour developed in a frontier territory such as the maritime banks of the northwest coast of Spain which is the so-called “subsector” the gatherers walk from the Galician (Spain. Of a field in such work we have half analyzed occupational segregation because of gender in the thread of the conditions that traditionally developed these jobs, while the same protagonists hearings trajectory traveled by the collective female for the “professional” consolidation.

    El siguiente artículo muestra la trayectoria del trabajo femenino desarrollado en un territorio de frontera como son las riberas marítimas del litoral noroeste de la Península Ibérica. Es el denominado “subsector” de las mariscadoras a pie de las rías bajas gallegas. A partir de un trabajo de campo en dicho entorno hemos analizado la segregación ocupacional en razón al género, al hilo de las condiciones en que tradicionalmente se desarrollaban dichas faenas. Mientras tanto las protagonistas narraron el itinerario recorrido por el colectivo femenino para la consolidación “profesional” del oficio de mariscadora.

  5. Una aproximación a la obra El cielo bajo los pies de Elsa Plaza y a la construcción del arquetipo de “la vampira del carrer Ponent”

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    Laia Manonelles Moner

    2015-10-01

    Full Text Available A partir de la novela El cielo bajo los pies (2009 de la historiadora y novelista Elsa Plaza, se revisará la construcción del mito de un personaje que deviene un chivo expiatorio de la tensión social que se vivía en Barcelona a principios del siglo XX. Se analizará cómo la obra de Elsa Plaza se aproxima al caso de Enriqueta Martí Ripoll, conocida por la prensa sensacionalista como la "vampira del Raval", con el objetivo de perfilar el contexto social, económico, político y cultural de una época ávida de crear figuras arquetípicas que canalizaran el creciente malestar.

  6. "Yo, Bernal Díaz del Castillo": ¿Soldado de a pie o idiota sin letras?

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    Verónica Cortínez

    2016-04-01

    Full Text Available Este artículo expone que la originalidad de la Historia verdadera de la conquista de la Nueva España radica en la escisión del "Yo" narrativo. La distancia temporal que separa al héroe del narrador crea una tensión entre propósitos irreconciliables. En este sentido, es ésta la historia de la desaveniencia entre ambos Bernales. This article shows that the originality of the Historia verdadera de la conquista de la Nueva España lies in the schism of the narrative "I". The temporal distance wich separates the hero from the narrator creates a tension between irreconcilable purposes. In this sense, this is the story of the discord between the two Bernales.

  7. Aplicabilidad de la termometría digital por infrarrojos en la valoración vascular del pie

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    Rayo Rosado, Rafael

    2009-01-01

    La temperatura corporal es un parámetro muy utilizado a la hora de establecer un juicio clínico en diversos procesos patológicos. La medición de la temperatura con fines diagnósticos o termometría clínica, es sin duda una de las pruebas complementarias más frecuente que se realiza en los procesos de salud. Al hablar de termometría, se nos viene a la cabeza el uso de termómetros con la finalidad de conocer la temperatura corporal del sujeto y determinar si existen procesos febriles. Sin embarg...

  8. Obesidad infantil: factor de riesgo para desarrollar pie plano

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    Saldívar-Cerón, Héctor Iván; Garmendia Ramírez, Alberto; Rocha Acevedo, Marco Antonio; Pérez-Rodríguez, Pedro

    2015-01-01

    Introducción: En México, la prevalencia de sobrepeso y obesidad en escolares es del 34.4% (ENSANUT 2012). Esta puede inducir un círculo vicioso “pie plano-plantalgia-sedentarismo-obesidad”. Sin embargo, la presencia y grado de pie plano en escolares con obesidad no se ha descrito en la población mexicana. El objetivo del estudio fue determinar la prevalencia de pie plano y su asociación con obesidad en escolares de Tamaulipas, México. Métodos: Se realizó un estudio analítico, transversal c...

  9. Valoración del riesgo de pie diabético en el paciente anciano en una consulta de enfermería Assessing the risk of "diabetic foot" in the elderly patient in a nursery office

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    Antonio Martínez Sabater

    2009-06-01

    Full Text Available Dentro del trabajo diario del profesional de enfermería con los mayores, la atención al paciente con diabetes mellitus (DM supone una parte importante del quehacer diario. El pie diabético supone una de las complicaciones más frecuentes que van a suponer un mayor coste, no sólo a nivel físico, sino social y económico, tanto para el paciente como para la sociedad. Nos planteamos realizar un estudio descriptivo observacional sobre los hábitos higiénicos respecto al cuidado de los pies de los pacientes mayores de 60 años afectos de diabetes mellitus remitidos a la consulta de enfermería, encontrándose un déficit importante de cuidados podológicos en los pacientes estudiados. El profesional de enfermería, por el alto contacto que tiene con el paciente afecto de diabetes mellitus, es un factor importante en la prevención y detección precoz del pie diabético y de la promoción de hábitos saludables.Taking care of diabetes mellitus (DM patients is one of the main chores in geriatric nursery. "Diabetic foot" is the most common problem and it actually entails a great deal of expenses, physically, socially and economically speaking, as well for the patient as for the community. What we did was an observational and descriptive research about foot cleansing habits in diabetes mellitus patients over 60 years old and we found out a severe lack of chiropody care. Due to the fact their work involves having a close contact with diabetes mellitus patients, nursing professionals become an outstanding agent on an early detection and prevention of the "diabetic foot" in addition of improving healthy cleaning habits.

  10. Nordic walking as alternative physical activity for population with neuropathy on foot Marcha nórdica: actividad física alternativa en el cuidado del pie

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    P. Pérez

    2010-09-01

    Full Text Available

    During last decade, Nordic Walking (NW is more and more being practiced by the population. The benefits associated to NW are several, nevertheless, does not know their effect on plantar pressure. The objective on this study it emphasizes the analysis on the plantar pressure depend on speed and experience on NW vs gait. By means of a Pedobarography system, plantar pressures in 9 zones on foot were registered on 2 speeds (slow/fast and two conditions (NW versus gait. The results show as the NW experience owns a smaller pressure at the central-metatarsal zone (~ 50%, and increase at heel zone (~ 23% and first toe (~ 13% with respect to the gait. Also, these experts showed lees pressure at metatarsal zone (~ 40% during gait, and lees plantar pressure in practically all zones, even at increase the speed.
    Key Words:  gait, plantar pressure, nordic walking, speed.

    Durante la última década, la marcha con bastones denominada “Nordic Walking”, está siendo cada vez más practicada por la población. Son varios los beneficios asociados a este estilo de marcha, sin embargo, se desconoce su efecto en la presión plantar. Como objetivo en este estudio destaca el análisis de la velocidad y experiencia en la Marcha nórdica vs Marcha sobre la presión plantar. Mediante un sistema de Pedobarografía, se registraron las presiones plantares en 9 zonas del pie, empleando 2 velocidades (lenta/rápida, y en 2 condiciones: Marcha nórdica vs Marcha. Los resultados muestran que los sujetos con mayor  experiencia en la marcha nórdica poseen una menor presión en la zona de los metatarsianos centrales (~ 50%, y un incremento en la zona del talón (~ 23% y primer dedo (~ 13 % respecto a la marcha. Además, estos expertos mostraron menores presiones en la zona metatarsal (~ 40% durante la marcha, y una menor presión plantar en prácticamente todas

  11. Guía práctica para el diagnóstico y el tratamiento del síndrome del pie diabético Practical guide for the diagnosis and treatment of the diabetic foot syndrome

    Directory of Open Access Journals (Sweden)

    Jorge Luis Sell Lluveras

    2001-12-01

    Full Text Available Se sabe que el síndrome del pie diabético constituye una de las principales causas de morbilidad y discapacidad en los pacientes con diabetes mellitus y que un rápido reconocimiento y adecuado manejo de sus factores de riesgo pueden prevenir o retardar la aparición de úlceras, amputaciones y otras complicaciones. Sus causas se dividen en: neuropáticas, angiopáticas, infecciosas y traumáticas. Se afirma que un detallado interrogatorio y exhaustivo examen físico ofrecen hasta el 90 % del diagnóstico etiológico, lo cual se corroborará con los exámenes complementarios que incluyen tanto los indispensables como los más específicos estudios imagenológicos. Durante las dos últimas décadas, se han alcanzado avances importantes en la comprensión de su fisiopatología y nuevas estrategias terapéuticas se han puesto en marcha. El enfoque actual para su tratamiento implica una atención individualizada y multidisciplinaria para cada paciente; la profilaxis, desempeña un papel fundamental y unida a los adelantos terapéuticos especializados garantizará un mejoramiento en la calidad de vida de estos enfermos. Este trabajo aporta una guía práctica para identificar, diagnosticar y tratar a los pacientes con síndrome del pie diabético, según los conocimientos actuales.It is known that the diabetic foot is one of the main causes of morbidity and disability in patients with diabetes mellitus and that a rapid examination and a right management of their risk factors can prevent or delay the appearance of ulcers, amputations and other complications. Its causes may be neuropathic, angiopathic infectious and traumatic. It is affirmed that a detailed questionnaire and an exhaustive medical examination offer up to 90 % of the etiological diagnosis, which is confirmed with the complementary tests that include both, the indispensable and the most specific imaging studies. During the last two decades, there have been significant advances in the

  12. Pied de Pulse

    NARCIS (Netherlands)

    2016-01-01

    This project has two aims. The first is to study and implement a fractal-like structure of circles inspired by Apollonian circles, combined with a pied de poule (houndstooth). The second aim is to push the integration of electric actuators in garments, using the power of algorithmic design and

  13. Amputación del miembro inferior por pie diabético en hospitales de la costa norte peruana 1990 - 2000: características clínico-epidemiológicas

    Directory of Open Access Journals (Sweden)

    David Escalante Gutiérrez

    2003-07-01

    Full Text Available Objetivo: Identificar las características clínico-epidemiológicas de la amputación del miembro inferior por pie diabético en pacientes de la costa norte peruana durante los años 1990-2000. Materiales y métodos: Estudio descriptivo, retrospectivo, basado en recolección de información de pacientes atendidos en cinco hospitales de cuatro capitales de departamento de la costa norte peruana. Se recolectaron datos demográficos y de la enfermedad (diagnóstico y manejo. Resultados: Se incluyeron 250 pacientes procedentes de: Hospital JAMO de Tumbes 8,4%, Hospital Cayetano Heredia de Piura 40,0%, Hospital Regional Docente Las Mercedes de Lambayeque 18,0%, Hospital Belén 24,4% y Hospital Regional Docente de La Libertad 9,2%. El 61,2% fueron varones y la edad promedio fue 63,5±10 años. El 98,4% presentaron diabetes mellitus tipo 2, 56,5% sufrieron amputaciones mayores (p<0,05 y 10,4% amputaciones mayores secuenciales. El tiempo de reamputación fue ≤ 24 meses en 71,3% (p<0,05. Se identificó estadiaje de pie diabético según Wagner en 44 (11,8%, con un cuarto grado en 45,0%. El tiempo con enfermedad de los pacientes hasta la primera amputación fue entre 11 y 20 años (31,2%, destacando 13,6% casos con pie diabético como primera forma de presentación de DM y 2,5% con sintomatología de larga data pero que carecían de diagnóstico de diabetes mellitus. De las amputaciones, sólo el 8,3% fueron sometidas a debridaciones y el 4,4% a revascularización. Conclusiones: Se encontró una frecuencia importante de pie diabético. Los problemas detectados fueron: carencia de ayuda diagnóstica complementaria, falta de aplicación de procedimientos de salvataje previos a la amputación y no fueron evaluados integralmente los pacientes. Estos problemas deben ser resueltos para mejorar la calidad de vida y reducir las amputaciones innecesarias.

  14. El pie en la danza clásica_

    Directory of Open Access Journals (Sweden)

    Nuria Massó Ortigosa.

    2010-05-01

    Full Text Available La danza es una forma de lenguaje que utiliza como instrumento al propio cuerpo, y su práctica continuada genera cambios y adaptaciones debidas a las altas exigencias de esta actividad. En este artículo se analizan las demandas, patologías y exigencias osteo-musculares del pie en la danza clásica. Para ello se ha partido del análisis de las estructuras del pie en distintas posiciones técnicas como la punta, media punta, o el “en dehors”. Como consecuencia de estas demandas de esfuerzo, se observa que una alta proporción de bailarines/as presenta alteraciones en el pie como hallux valgus y dedos en garra. También se ha estudiado la implicación en las técnicas básicas del pie de danza clásica de los músculos tríceps sural, peroneo lateral largo, tibial posterior, flexor largo y flexor corto del dedo gordo, tibial anterior, extensor propio del dedo gordo, abductor del dedo gordo, así como la musculatura interósea y plantar.

  15. Post irradiation effects (PIE) in integrated circuits

    International Nuclear Information System (INIS)

    Barnes, C.E.; Shaw, D.C.; Fleetwood, D.M.; Winokur, P.S.

    1992-01-01

    Post Irradiation Effects (PIE) ranging from normal recovery catastrophic failure have been observed in integrated circuits during the PIE period. These variations indicate that a rebound or PIE recipe used for radiation hardness assurance must be chosen with care. In this paper, the authors provide examples of PIE in a variety of integrated circuits of importance to spacecraft electronics

  16. MORFOESTRUCTURAS DEL FONDO OCEÁNICO MEXICANO

    Directory of Open Access Journals (Sweden)

    José Lugo Hubp

    2017-05-01

    están presentes las morfoestructuras principales reconocidas para el océano mundial: plataforma y talud continentales, pie del continente, trincheras, cuencas de mar marginal, montañas aisladas, crestas montañosas diversas (de arco insular, de planicie abisal, borderland, dorsal y fosa rift. Las anteriores se representan en una carta de morfoestructuras que complementa a las existentes fisiográficas y geológicas de la tierra firme. En el fondo oceánico mexicano se llevan a cabo intensos movimientos que han influido e influyen en la formación del relieve submarino y continental.

  17. La ortopodología en el pie de riesgo (2ª Parte)

    OpenAIRE

    Céspedes Céspedes, Tomás; Dorca Coll, Adelina; Concustell Gonfaus, Josep; Cuevas Gómez, Rafael; Sacristán Valero, Sergi

    1994-01-01

    Los autores presentan y describen varios casos clínicos podológicos, en los que aprecia: Una alteración y limitació progresiva de las funciones del pie y como resultado un transtomo general del equilibrio estático y dinámico: características que corresponden al ya descrito «Pie de riesgo'

  18. Stovetop Earth Pecan Pie

    Science.gov (United States)

    Robin, C. M.

    2005-12-01

    Many fluid mechanical experiments with direct applications to Earth Science are performed with sugary syrups using conceptually straightforward procedures. Corn syrup has indeed proven to be a godsend for those studying convection and related non-linear phenomena. In addition, however, it gives experimentalists a deep physical intuition for the interior workings of hot planets. The basic concepts behind plate tectonics and mantle convection are not difficult; indeed, although they may not be aware of it, most students probably have a basic intuitive understanding of fluid mechanics gained in their daily life. However, the large size and long time scale of geophysical processes may be quite intimidating to young students. Even a simple geophysical experiment requires a complicated array of coolers, heaters and measuring and recording equipment. It is of interest to introduce students to the geodynamical concepts that can be visualized in a high-tech lab using familiar processes and equipment. Using a homemade apparatus and grocery store supplies, I propose using a 'Stove-top Earth pecan pie' to introduce simple geodynamic concepts to middle- and high-school students. The initially cold syrup heats up and the pecans begin to float (continent formation), the syrup begins to convect (mantle convection), and convection slows down after the heat is removed (secular cooling). Even Wilson cycles can be simulated by moving the pan to one side or the other of the stovetop or heating element. The activity formally introduces students to convection and its application to the earth, and makes them think about plate motion, heat transfer, scaling, and experimental procedures. As an added bonus, they can eat their experiments after recess!

  19. El dolor patelofemoral en el baile flamenco y su relación con el pie

    Directory of Open Access Journals (Sweden)

    José M. Castillo-López

    2017-05-01

    Full Text Available El dolor patelofemoral es uno de los desórdenes más comunes que afectan a la rodilla. De las lesiones descritas en el baile flamenco profesional, destacan las relacionadas con el pie y la rodilla, en relación al microtraumatismo repetido del gesto técnico del zapateado y a la flexión de rodilla mantenida que requiere. El objetivo de este estudio es determinar la presencia de dolor patelo femoral en profesionales del baile de flamenco y comprobar si existe relación alguna con el pie pronador y genus valgo. En el estudio han participado 46 profesionales del baile flamenco, 38 bailaoras y 8 bailaores, con una carga media de 25.4 ± 8.25 horas de baile semanales. El 34.78% de los participantes presentaban dolor patelofemoral. El 24% presentaba también genus valgo. Se encontró un 34.78% de pies pronadores. La asociación de pies pronadores y genus valgo fue del 31.25%, mientras que la asociación de pies pronadores y dolor patelofemoral fue de 43.75 % de los casos. Factores predisponentes de esta patología se dan en la práctica del baile flamenco: el impacto repetitivo, una posición mantenida y forzada de la rodilla en un rango concreto, desplazamientos y los giros bruscos. Como conclusión, se demuestra relación directa entre la presencia de pies pronadores y dolor patelofemoral en el baile flamenco. Así como entre pies pronadores y genus valgo. Estudios científicos actuales demuestran la utilidad de soportes plantares en este síndrome. La incidencia de pies pronadores y dolor patelofemoral hace recomendable estudios biomecánicos y podológicos y el uso de soportes plantares personalizados en cada caso.

  20. PIE analysis for minor actinide

    International Nuclear Information System (INIS)

    Suyama, Kenya

    2005-01-01

    Minor actinide (MA) is generated in nuclear fuel during the operation of power reactor. For fuel design, reactivity decrease due to it should be considered. Out of reactors, MA plays key role to define the property of spent fuel (SF) such as α-radioactivity, neutron emission rate, and criticality of SF. In order to evaluate the calculation codes and libraries for predicting the amount of MA, comparison between calculation results and experimentally obtained data has been conducted. In this report, we will present the status of PIE data of MA taken by post irradiation examinations (PIE) and several calculation results. (author)

  1. Una nueva especie de rana de cristal del género Hyalinobatrachium (Anura: Centrolenidae del Delta del Río Orinoco, Venezuela

    Directory of Open Access Journals (Sweden)

    J. Celsa Señaris

    2001-12-01

    Full Text Available Se describe una nueva especie de Hyalinobatrachium del grupo fleischmanni, H. mondolfii, de las planicies inundables del delta del río Orinoco, Venezuela. Hyalinobatrachium mondolfii se distingue del resto de las especies del grupo por la siguiente combinación de caracteres: peritoneo parietal translúcido, pericardio y peritoneos visceral y hepático blancos, coloración dorsal en vida verde claro con diminutos puntos amarillos y en preservativo crema uniforme con diminutos melanóforos oscuros (visibles solo bajo magnificación, huesos blancos en vida, palmeadura de manos y pies extensa, cabeza redondeada en vista dorsal e inclinada en vista lateral, piel dorsal granular y un canto con frecuencia fundamental superior a los 5 000 HzA new species of Hyalinobatrachium of the fleischmanni group, H. mondolfii, is described from the Orinoco delta floodplains in Venezuela. This new species can be distinguished from other congeners by the following combination of characters: parietal peritoneum clear, pericardium white, visceral and hepatic peritoneum white, color in life pale green with diminute yellow spots and, in preservative, cream with small dark melanophores (visible only under magnification, bones white in life, extense webbing, snout round in dorsal view and inclinate in lateral view, dorsal skin granulate and a advertisement call with a fundamental frequency greater than 5000 Hz

  2. "En la boca de las nubes" (A la boca dels núvols y con los pies en el suelo. Ramon Vinyes: contra la literatura, la vida

    Directory of Open Access Journals (Sweden)

    Jordi Marrugat i Doménech

    2005-01-01

    Full Text Available Este artículo propone una lectura unitaria del volumen de narraciones de Ramon Vinyes En la boca de las nubes (1946. Además, va a las fuentes de las cuales surge la estética del libro —la narrativa catalana y europea de los años 20-30 y el pensamiento teórico de Vinyes— para explicar como el autor decadentista de La ardiente cabalgata (1909 acaba por escribir un libro tan alejado de los posicionamientos que había mantenido durante el Modernismo. Y es que si en 1909 Vinyes decantaba la balanza de la dicotomía artevida hacia el primero de estos términos, en 1946, después de haber vivido una guerra civil y dos guerras mundiales, la decanta radicamente hacia el segundo. Así, el lector podrá encontrar sugestivas comparaciones entre Vinyes y escritores como T. Gautier, Villiers de l’Isle-Adam, Gabriele d’Annunzio o Gabriel Alomar por lo que se refiere a su época modernista; entre Vinyes y Malraux, Saint-Exupéry, V. Woolf, Joan Oliver o Salvador Espriu, por lo que se refiere a los años 30; y entre Vinyes i Pere Calders o Lluís Ferran de Pol, por lo que se refiere al exilio

  3. Localización y evolución del comercio y servicios a pie de calle en los entornos urbanos. Factores locales frente a la multi-accesibilidad. El caso de la ciudad de Madrid.

    Directory of Open Access Journals (Sweden)

    José Carpio-Pinedo

    2014-06-01

    Full Text Available ResumenEl comercio y los servicios a pie de calle, articuladores de la vida urbana, viven un periodo de transformación, compañado de un cambio en el modelo de ciudad existente. Estudios cualitativos apuntan a una ‘ciudad dual’: concentraciones de pequeños locales en entornos densos y accesibles a pie y en transporte público, frente a grandes superficies como enclaves periféricos accesibles sólo en vehículo privado. Se polariza la discusión sin matizar la distinción entre aspectos locales del entorno (como la densidad con otros que dependen de la posición metropolitana (como la accesibilidad.El objetivo de este trabajo es distinguir y cuantificar los factores urbanos asociados más intensamente con la concentración de establecimientos y con su evolución más reciente. Para ello, se analizan 84 entornos de Madrid, mediante Sistemas de Información Geográfica, modelos de transporte y métodos estadísticos. Se valoran datos de 2010 y evolución desde 2004, en relación con las características que atañen a aspectos morfológicos, usos planificados, la población y el empleo. Así mismo, se valora la relación con la accesibilidad en modos sostenibles (peatonal y transporte público, planteando el concepto de “multi- accesibilidad” y demostrando su mayor pertinencia y poder explicativo.Palabras claveComercio urbano, accesibilidad, nodo-lugar, Madrid.AbstractRetail and services in urban areas are in a state of evolution. Due to their implications for urban life, this fact implies a necessary change to the model of the city. Descriptive works refer to a ‘dual city’: concentrations of small shops that are easily accessible (either on foot or way of public transportation at quite population dense contexts and to the contrary larger shopping malls which are found in suburban areas where people often move by private vehicle.  Discussion in the field is polarized and yet there is no clear distinction between urban environmental

  4. The MEGAPIE PIE sample preparation

    International Nuclear Information System (INIS)

    Wohlmuther, M.; Boutellier, V.; Dai, Y.; Gavillet, D.; Geissmann, K.; Hahl, S.; Hammer, B.; Lagotzki, A.; Leu, H.; Linder, H.P.; Kalt, A.; Kuster, D.; Neuhausen, J.; Schumann, D.; Schwarz, R.; Schweikert, H.; Spahr, A.; Suter, P.; Teichmann, S.; Thomsen, K.; Wiese, H.; Wagner, W.; Zimmermann, U.; Zumbach, C.

    2015-01-01

    On the way towards Accelerator-driven Systems (ADS), the MEGAPIE (Mega-Watt Pilot Experiment) project is one of the key milestones. The MEGAPIE project aimed to prove that a liquid Lead-Bismuth-Eutectic (LBE) spallation target can be licensed, planned, built, operated, dismantled, examined and disposed. The project has finished the phase of producing the samples for Post-irradiation Examination (PIE). Samples to study structural material property changes due to the harsh environment of high temperatures, contact with flowing liquid metal (LBE), proton and neutron irradiation will be investigated by all partner laboratories (CEA, CNRS, ENEA, KIT, PSI and SCK-CEN). (authors)

  5. Ontogenetic variation in the plumage colour of female European Pied Flycatchers Ficedula hypoleuca

    OpenAIRE

    Potti, Jaime; Canal, David; Camacho, Carlos

    2014-01-01

    Although variation in the dorsal plumage colour of male European Pied Flycatchers Ficedula hypoleuca has received a great deal of attention, females of the species have been usually considered to be nearly uniformly monochromatic brown. Using reflectance spectrophotometry, we explore the age-dependent variation of plumage colour in females. We disentangle the within- and between-individual effects of this pattern and show a within-individual darkening of the mantle colour with age, whereas di...

  6. 9 CFR 319.500 - Meat pies.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Meat pies. 319.500 Section 319.500... ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION DEFINITIONS AND STANDARDS OF IDENTITY OR COMPOSITION Meat Food Entree Products, Pies, and...

  7. Geocronología e historia volcánica del complejo volcánico del Teide y las dorsales de Tenerife

    OpenAIRE

    Carracedo, Juan Carlos; Rodríguez Badiola, Eduardo; Guillou, Hervé; Scaillet, Stéphane; Paterne, Martine; Pérez Torrado, Francisco José; Paris, Raphael; Fra-Paleo, U.; Hansen Machín, Álex

    2006-01-01

    Estos trabajos geológicos no habrían podido realizarse sin la oportuna y generosa financiación de Obra Social y Cultural de la Caja General de Ahorros de Canarias y el Laboratoire des Sciences du Climat et de l’Environnement (CEA-CNRS), Francia. Posteriormente, por la financiación dentro del marco del Plan Nacional de I+D, del proyecto de investigación CGL2005-00239.

  8. Gestión del urbanismo y administración urbana: los pies de barro en el despliegue territorial del neoliberalismo en Chile. / Management planning and urban management: feet of clay in the territorial deployment of neoliberalism in Chile.

    Directory of Open Access Journals (Sweden)

    Gaete Feres, Héctor

    2003-01-01

    Full Text Available En Chile, el abordaje eficiente de los problemas urbanos requiere enfrentar un asunto central pero rezagado de los procesos de modernización impulsados en el marco del modelo económico neoliberal vigente: la ineficiencia en la administración y gestión del desarrollo territorial. Ambas constituyen lastres que afectan el desempeño del sistema económico y el logro de los objetivos del país en calidad de vida para las personas. El artículo busca relevar, revisar el estado del arte y proponer líneas de trabajo hacia soluciones./Management of urbanism and urban administration. The Mud Feet in the Territorial Deployment of the Neoliberalism in Chile.In Chile, the efficient boarding of the urban problems requires to face a central but left behind subject of the impelled processes of modernization in the frame of the effective neoliberal economic model: inefficiency in the administration and management of the territorial development. Both constitute ballasts that affect the performance of the economic system and the profit of the objectives of the country in quality of life for the people. I articulate looks for to release, to review the state-of-the-art and to propose lines of work towards solutions.

  9. Representações sociais do pé diabético para pessoas com diabetes mellitus tipo 2 Representaciones sociales del pie diabético para personas con diabetes mellitus tipo 2 Social representations of diabetic foot for people with type 2 diabetes Mellitus

    Directory of Open Access Journals (Sweden)

    Maria Seloi Coelho

    2009-03-01

    Full Text Available Trata-se de uma pesquisa qualitativa que objetivou compreender as representações sociais do pé diabético para pessoas com diabetes mellitus tipo 2. Foram realizadas entrevistas semi-estruturadas, com dez pessoas com diabetes mellitus que participavam de um grupo de convivência. Da análise de conteúdo emergiram duas categorias: a doença do pé com alterações percebidas e ameaças presentes e; o cuidado com os pés, com o cuidado como preocupação com o futuro e não cuidado como sentimento de culpa. Os resultados mostraram que movidos pelas representações de alterações e ameaças os sujeitos buscam no cuidado uma esperança de não desenvolver a doença do pé ou controlar a situação. Quando o não-cuidado ocorre, surge o sentimento de culpa por terem conhecimentos e não se cuidarem. As representações sociais contribuíram na busca da compreensão do modo como os sujeitos com diabetes mellitus constroem saberes que expressam sua identidade e guiam seus comportamentos, especialmente vinculado ao pé diabético.Se trata de una investigación cualitativa que tuvo como objetivo comprender las representaciones sociales de pies diabético para personas con diabetes mellitus tipo 2. Fueron realizadas entrevistas semi-estructuradas, con diez personas con diabetes mellitus que participaban de un grupo de convivencia. Del análisis de contenido emergieron dos categorías: la enfermedad del pie con alteraciones percibidas y amenazas presentes y; el cuidado con los pies, con el cuidado como preocupación con el futuro y no cuidado como sentimiento de culpa. Los resultados mostraron que movidos por las representaciones de alteraciones y amenazas los sujetos buscan en el cuidado una esperanza de no desarrollar la enfermedad del pie o de controlar la situación. Cuando ocurre el no cuidado surge el sentimiento de culpa por tener los conocimientos y no utilizarlos. Las representaciones sociales contribuyeron en la búsqueda de la comprensi

  10. Correlación entre los interhusos del ritmo alfa, el EMG de los gemelos y la oscilación de vaivén del individuo de pie

    Directory of Open Access Journals (Sweden)

    Jose H. Peñaloza Rojas

    1994-10-01

    Full Text Available En sujetos adultos normales se registraron simultáneamente: el electroencefalograma (EEG occipital, el electromiograma (EMG de los músculos gemelos y el movimiento oscilatorio de vaivén del individuo (EOsG en bipedestación, con ojos cerrados y abiertos. Mientras permanecen los sujetos experimentales con los ojos cerrados, el EEG muestra los husos de ritmo alfa bien integrados, unidos o separados por los interhusos los cuales son de duración y frecuencia variables. EI EMG es intermitente y las descargas de los potenciales musculares son de duración breve. EI EOsG esta formado por ondas de amplitud y duración variables. De la observación cuidadosa de estos registros simultáneos se puede inferir la existencia de una correlación temporal entre los tres eventos: primero los interhusos se registran previamente a la aparición del EMG, segundo el EMG precede al EOsG y tercero el EOsG aparece finalmente, como manifestación del vaivén del sujeto experimental. Es decir, la activación cerebral (interhusos influye sobre los músculos gastrocnemios (EM G para que estos se contraigan, enderezcan el cuerpo y corrijan la posición corporal. Como consecuencia de esto, se obtiene el EOsG. Por 10tanto.estos resultados sugieren que los interhusos son un fenómeno electrofisiológico normal resultante de la activación momentánea cerebral y que se registran después de que el individuo ha aprendido a mantenerse en bipedestación.

  11. PIE DIABÉTICO: ¿PODEMOS PREVENIRLO?

    Directory of Open Access Journals (Sweden)

    Dra. Oriana Paiva M.

    2016-03-01

    Full Text Available La diabetes es una enfermedad epidémica, con más de 400 millones de personas diagnosticadas en la actualidad. Las úlceras del pie son una de las complicaciones crónicas más frecuentes de esta población, con un riesgo acumulado de desarrollarla a lo largo de la vida de 15%. La neuropatía y la enfermedad vascular son las principales causas de su aparición. Las amputaciones no traumáticas en diabéticos son 15 veces más frecuentes que en la población general, superando en 2 a 3 veces la tasa en hombres que en mujeres. El 80% se puede prevenir. La clave para ello incluye un examen periódico del pie a todo diabético al menos 1 vez al año, educación del paciente en autocuidado, para que logre identificar precozmente la aparición de lesiones evitando mayores complicaciones, un zapato adecuado y un buen control metabólico.

  12. Defective Reduction in Frozen Pie Manufacturing Process

    Science.gov (United States)

    Nooted, Oranuch; Tangjitsitcharoen, Somkiat

    2017-06-01

    The frozen pie production has a lot of defects resulting in high production cost. Failure mode and effect analysis (FMEA) technique has been applied to improve the frozen pie process. Pareto chart is also used to determine the major defects of frozen pie. There are 3 main processes that cause the defects which are the 1st freezing to glazing process, the forming process, and the folding process. The Risk Priority Number (RPN) obtained from FMEA is analyzed to reduce the defects. If RPN of each cause exceeds 45, the process will be considered to be improved and selected for the corrective and preventive actions. The results showed that RPN values decreased after the correction. Therefore, the implementation of FMEA technique can help to improve the performance of frozen pie process and reduce the defects approximately 51.9%.

  13. Transferencia del dorsal ancho para lesiones irreparables del manguito rotador. Técnica quirúrgica y evaluación de una serie de 20 pacientes

    Directory of Open Access Journals (Sweden)

    Rafael Rodríguez

    2016-04-01

    promedio de 1 y por la mejoría de la elevación y rotación externa antes mencionada. La evaluación radiológica post operatoria, siguiendo los criterios de Hamada no evidenció una progresión significativa hacia la artropatía por rotura del manguito.

  14. Pie plano astrágalo vertical asociado a sinovitis. Fases de tratamiento

    OpenAIRE

    Planell i Mas, Elena de; Bonilla Toyos, Elvira

    2008-01-01

    El pie plano astrágalo vertical congénito es una deformidad poco frecuente que se puede encontrar de forma aislada, dentro de un cuadro polimalformativo o en relación con afectaciones neurológicas. Se caracteriza por una luxación del escafoides por encima del astrágalo,lo que provoca un pie rígido o de dificil manipulación. En este artículo los autores describen un caso clínico de un paciente que acude a consulta por presentar una inflamación dolorosa en la zona de la cabeza del astrágalo del...

  15. Efectividad de un programa educativo en pacientes con pie diabético de riesgo

    Directory of Open Access Journals (Sweden)

    Olga Lidia Pereira Despaigne

    2015-01-01

    Full Text Available Se realizó un estudio de intervención terapéutica educativa en pacientes con pie diabético de riesgo, atendidos en la Consulta de Angiopatía Diabética del Hospital Provincial Docente Clinicoquirúrgico "Saturnino Lora Torres" de Santiago de Cuba, desde enero del 2011 hasta igual mes del 2013, a fin de determinar la efectividad de un programa educativo (momento de la intervención al respecto. Fueron indicativos de pie diabético de riesgo (momento del diagnóstico, la úlcera previa o amputación, la neuropatía periférica con pérdida de sensación protectora, la enfermedad arterial periférica, la hiperqueratosis y la afección grave de las uñas, la deformidad en el pie, la movilidad articular reducida, el calzado inadecuado, el tabaquismo, la edad avanzada, la larga evolución de la diabetes mellitus y la falta de educación diabetológica en pie diabético. La información fue analizada y procesada mediante las pruebas de hipótesis de Mann-Whitney y de comparación de medias, con un error de 5 %, y se obtuvo que con este programa (momento evaluativo se disminuyera la afectación que el pie diabético ocasiona a la actividad social, laboral y familiar de estas personas, así como el elevado costo económico, tanto para ellos como para el sistema de salud

  16. La dorsal NE de Tenerife: hacia un modelo del origen y evolución de los rifts de islas oceánicas

    Directory of Open Access Journals (Sweden)

    Delcamp, A.

    2009-06-01

    primordial, plume-related fractures acting throughout the entire growth of the islands. Basaltic volcanism forms the bulk of the islands and rift zones. However, collapses of the flanks of the rifts disrupt their established fissural feeding system, frequently favouring magma accumulation and residence at shallow emplacements, leading to differentiation of magmas, and intermediate to felsic nested eruptions. Rifts and their collapse may therefore act as an important factor in providing petrological variability to oceanic volcanoes. Conversely, the possibility exists that the presence of important felsic volcanism may indicate lateral collapses in oceanic shields and ridge-like volcanoes, even if they are concealed by post-collapse volcanism or partially mass-wasted by erosion.El Rift NE de Tenerife, conocido localmente como la Dorsal de La Esperanza, es un excelente ejem plo de un rift persistente y recurrente. Su estudio ha aportado evidencias significativas del origen y diná mica de este tipo de estructuras volcánicas. Los rifts son posiblemente las estructuras más relevantes en la geología de las islas volcánicas oceánicas: 1. Controlan, tal vez desde su inicio, la construcción de los edificios insulares; 2. Son elementos sustanciales en la configuración (forma y topografía de estas islas; 3. Dan origen a sus principales formas del relieve y el paisaje; 4. Al concentrar la actividad eruptiva, son asimismo estructuras cruciales en la distribución del riesgo volcánico; 5. Condicionan la distribución de recursos naturales básicos, como el agua subterránea. En las Canarias están muy bien representados tanto los rifts típicos de los estadios juveniles de desarrollo en escudo, como los más tardíos, correspondientes a las fases de rejuvenecimiento post-ero sivo. El Rift NE es un buen ejemplo de este último tipo de rifts. El Rift NE se ha desarrollado en tres etapas diferentes separadas por periodos más largos de quiescencia o actividad reducida. La primera

  17. Pied de pulse: packing embroidered circles and coil actuators in pied de poule (houndstooth)

    NARCIS (Netherlands)

    Feijs, L.M.G.; Toeters, M.J.; Torrence, E.; Torrence, B.; Sequin, C.; McKenna, D.; Fenyvesi, K.; Sarhangi, R.

    2016-01-01

    We report on the integration of fractal-like structures inspired by Appolonian circles with pied de poule (houndstooth) fabric patterns, and on the use of electric actuators in garments made with digital embroidery techniques.

  18. Atividade eletromiográfica durante o agachamento unipodal associado a diferentes posições do pé Actividad electromiográfica durante el agache unipodal asociado a diferentes posiciones del pie Electromyographic activity during one-legged squatting under different foot positions

    Directory of Open Access Journals (Sweden)

    Gabriel Ribeiro

    2007-02-01

    Full Text Available O objetivo principal deste estudo foi quantificar a atividade muscular durante a realização de agachamento unipodal com variações na técnica. Oito voluntários saudáveis realizaram agachamentos associados a cinco tipos de posição do pé: posição neutra, sobre cunha com 10º de declive, sobre cunha com 10º de aclive, sobre cunha com 10º de inclinação medial e sobre cunha com 10º de inclinação lateral. Foram avaliados os dados eletromiográficos dos músculos vasto medial oblíquo, vasto lateral, reto femoral, bíceps femoral, gastrocnêmio lateral e tibial anterior, utilizando a ANOVA fator único. O valor eletromiográfico integrado de todos os músculos não foi estatisticamente diferente nos cinco tipos de posição do pé. Os resultados deste estudo sugerem que diferentes tipos de posicionamento do pé durante o agachamento unipodal não provocam alterações no padrão de recrutamento muscular.El objetivo principal de este estudio ha sido cuantificar la actividad muscular durante la realización de agachamiento unipodal con variaciones en la técnica. Ocho voluntarios saludables realizaron agachamientos asociados a cinco tipos de posición del pie: posición neutra, sobre cuña con 10º de declive, sobre cuña con 10º de elevación, sobre cuña con 10º de inclinación media y sobre cuña con 10º de inclinación lateral. Fueron evaluados los datos electromiográficos de los músculos vasto medial oblicuo, vasto lateral, recto femoral, bíceps femoral, gastrocnemio lateral y tibial anterior, utilizando ANOVA factor único. El valor electromiográfico integrado de todos los músculos no fue estadísticamente diferente en los cinco tipos de posición del pie. Los resultados de este estudio sugieren que diferentes tipos de posicionamiento del pie durante el proceso de agachamiento unipodal no provocan alteraciones en el padrón de reclutamiento muscular.The specific aim of this study was to quantify muscle activity while

  19. Ejercicios técnico-tácticos para la ejecución de los pases con el empeine exterior del pie en futbolistas de la categoría 12-13 años / Technical-tactical exercises for the execution of the passes with the outer instep of the foot in soccer players of the category 12-13 years

    Directory of Open Access Journals (Sweden)

    Dayron Alberto Rice-Nelson

    2016-08-01

    Full Text Available Resumen El proceso de preparación técnico-táctica ofensiva en el fútbol constituye un pilar fundamental para lograr un buen desarrollo del juego y también alcanzar resultados favorables cuando se compite. Se pudo comprobar mediante un diagnóstico que los futbolistas de la categoría 12-13 años del Combinado Deportivo Previsora, municipio Camagüey, presentan insuficiencias en la ejecución de los pases con el empeine exterior del pie mientras compiten o entrenan, lo que afecta sus resultados; por tanto, esta investigación tiene como objetivo diseñar juegos y ejercicios que favorezcan la ejecución técnico-táctica de los pases con el empeine exterior del pie. Para ello se emplearon diversos métodos y técnicas como la entrevista, la revisión documental, la observación a sesiones de entrenamientos y la observación a competencias. Estos arrojaron como resultados que la ofensiva era poco variable, poco sorpresiva, con una constante pérdida de balones en su desarrollo. La elaboración del conjunto de juegos y ejercicios favorece la correcta ejecución técnico-táctica de los pases con el empeine exterior del pie y eleva el nivel de preparación deportiva. Abstract The process of technical-tactical preparation offensive in football is a fundamental pillar to achieve a good development of the game and also achieve a favorable outcome when competing. It was possible to verify by means of a diagnosis that the soccer players of the category 12-13 years of Combined Sport Previsora, municipality Camagüey, present insufficiencies in the execution of the passes with the outside instep of the foot while competing or training, which affects the results of its Football activity. Therefore, the present research aimed to design a set of games and exercises that favor the technical-tactical execution of the passes with the outer instep of the foot. For this, various methods and techniques were used, such as interviewing, document review, observing

  20. Diseño y manufactura de pie Protésico

    OpenAIRE

    Hernández Martin, John Alexander; Parra Piñeros, Luis Alberto; Pinzón Pinzón, Cesar Agusto; Bejarano Peña, Oscar Heli; Romero Gutiérrez, Jairo Alberto; García Benavides, Pedro Eladio

    2017-01-01

    El término prótesis hace referencia al dispositivo que sustituye o compensa la pérdida de un miembro perdido, para el caso objeto de estudio, se da en una prótesis de miembro inferior, en el caso de una amputación de miembros inferiores a nivel transtibial, el pie es el elemento ausente más significativo ya que asume la estabilidad mínima del cuerpo del paciente, además de interferir en el balance intrínseco del cuerpo humano. Por lo anteriormente descrito uno de los pilares más importantes d...

  1. Impacto de las unidades a pie de carretera en las interferencias en redes vehiculares

    OpenAIRE

    Hernández Gañán, Carlos; Reñé Vicente, Sergi; Mata Diaz, Jorge; Alins Delgado, Juan José

    2013-01-01

    Las redes ad hoc vehiculares (VANETs) han emergido como una tecnolog´ıa clave que posibilita el despliegue diversas aplicaciones. Proporcionar seguridad a los servicios de informaci´on y entretenimiento en estos entornos requiere del uso de unidades a pie de la carretera (RSU) como puertas de acceso a los recursos solicitados. Idealmente, las RSUs deben desplegarse para proporcionar conectividad continua. Si bien esto aumenta la capacidad y cobertura, tambi´en acarrea un ...

  2. Recent and future PIE activities in KAERI

    International Nuclear Information System (INIS)

    Ahn, Sangbok; Ryu, Woo-seok; Hong, Kwonpyo; Jeon, Yongbum; Kim, Dosik; Choo, Yongsun

    2012-01-01

    KAERI has two PIE hot cell facilities. One is Irradiated Material Examination Facility (IMEF) to examine irradiated nuclear fuels and core structural materials at HANARO, and the other is a Post Irradiation Examination Facility (PIEF) to do the operated PWR nuclear fuels and skeleton. Their activities are categorized by hot cell examinations, new technique developments, maintenance of facility utilities and a public acceptance work. In the past three years hot cell tests were executed over 2,000 times related to R and D projects of the future and next generation reactors such as SMART, U-Mo fuels, I-NERI etc., including 30 rods to be operated in domestic PWR's. To supply PIE data on time to the user schedules new equipment and techniques are being developed for 10 items which include an annealing fission gas release rate, thermal diffusivity measurement, a laser puncturing fission gas collection system and mechanical property measurements on PWR FA skeleton etc. For maintenance of facilities the aged utility equipment are refurbished and exchanged for new ones. The partly cracked and leaking building walls are completely repaired, and the aged electric UPS's, HVAC system parts, heating and cooling system are exchanged for new ones. Additionally efforts to upgrade the public acceptance for facility visiting events, open training courses to the university and graduated students have been made. Regarding the future of domestic R and D and a power reactor operating plan the demand for hot cell examinations will be steadily increased. Along with them new PIE techniques on TRISO fuels, minor actinide SFR fuels and CANDU fuels etc are required to be developed. New space to install small scale hot cells, and develop for the extreme conditioned test to meet future demands will be taken. (author)

  3. Lumbar dorsal ramus syndrome.

    Science.gov (United States)

    Bogduk, N

    1980-11-15

    Low back pain, referred pain in the lower limbs, and spasm of the back, gluteal, and hamstring muscles are clinical features which can be induced in normal volunteers by stimulating structures which are innervated by the lumbar dorsal rami. Conversely, they can be relieved in certain patients by selective interruption of conduction along dorsal rami. These facts permit the definition of a lumbar dorsal ramus syndrome, which can be distinguished from the intervertebral disc syndrome and other forms of low back pain. The distinguishing feature is that, in lumbar dorsal ramus syndrome, all the clinical features are exclusively mediated by dorsal rami and do not arise from nerve-root compression. The pathophysiology, pathology, and treatment of this syndrome are described. Recognition of this syndrome, and its treatment with relatively minor procedures, can obviate the need for major surgery which might otherwise be undertaken.

  4. Constructing and applying the fractal pied de poule (houndstooth)

    NARCIS (Netherlands)

    Feijs, L.M.G.; Toeters, M.J.; Hart, G.; Sarhangi, R.

    2013-01-01

    Time is ready for a fractal version of pied de poule; it is almost "in the air". Taking inspiration from the Cantor set, and using the analysis of the classical pattern, we obtain a family of elegant new fractal Pied de Poules. We calculate the fractal dimension and develop an attractive fashion

  5. AVANCES EN LA EVALUACIÓN DEL ESTADO DE CONCIENCIA: PAPEL DE LA EVALUACIÓN A PIE DE CAMA Y LAS TÉCNICAS DE NEUROIMAGEN EN EL PROCESO DIAGNÓSTICO

    Directory of Open Access Journals (Sweden)

    Davinia Fernández-Espejo

    2016-01-01

    Full Text Available El estado vegetativo se define clínicamente por la falta de conciencia de uno mismo y el entorno, junto con el mantenimiento de funciones básicas como la respiratoria, cardiaca, o los ciclos de sueño y vigilia. Se trata de pacientes incapaces de reaccionar de un modo intencional a la estimulación externa y que no manifiestan ninguna capacidad comunicativa. Estudios recientes han demostrado que en torno al 40% de estos pacientes han sido incorrectamente diagnosticados y se encuentran, en realidad, conscientes. Sin embargo, en los últimos años se ha producido una revolución en las herramientas disponibles para evaluar a estos pacientes. El presente artículo tiene como objetivo discutir el papel de las escalas de evaluación clínica estandarizadas, así como técnicas avanzadas de neuroimagen, en la reducción del alarmante error diagnóstico. Se revisarán el alcance y las limitaciones de cada aproximación para identificar signos de conciencia externos o encubiertos, y se presentará evidencia a favor de una evaluación multimodal, combinando la información clínica, estructural y funcional para garantizar el diagnóstico correcto en cada caso individual.

  6. Caracterización clínico epidemiológica de pacientes afectados por pie diabético

    Directory of Open Access Journals (Sweden)

    Dania Núñez Álvarez

    2018-01-01

    Full Text Available Introducción: el pie diabético constituye un problema de salud en los pacientes portadores de diabetes mellitus y se registra como la primera causa de amputación no traumática de los miembros. El conocimiento de sus particularidades clínico-epidemiológicas resulta de sumo interés. Objetivo: caracterizar clínica y epidemiológicamente a los pacientes con pie diabético neuroinfeccioso en el Hospital "Dr. Joaquín Castillo Duany" de Santiago de Cuba. Método: se realizó un estudio descriptivo retrospectivo. El universo estuvo constituido por 96 pacientes diagnosticados con pie diabético durante el periodo comprendido entre el 2011 y el 2015. Se emplearon variables demográficas y relacionadas con factores de riesgo generales y específicos del pie diabético. Resultados: el pie diabético predominó entre la cuarta y sexta décadas de vida (24,7 % y en pacientes del sexo femenino (59,7 %. La diabetes mellitus tipo 2 estuvo representada en el 52,5 %. Mientras el factor de riesgo general de pie diabético más frecuente fue la obesidad (56,7 %, la neuropatía diabética, como factor de riesgo específico se presentó en el 98,9 % de los enfermos estudiados. Conclusiones: el pie diabético predominó en la cuarta y sexta décadas de la vida y en el sexo femenino. El mayor porcentaje de los pacientes era portador de diabetes mellitus tipo 2. La obesidad, la neuropatía diabética periférica, el sobrepeso, y la hiperglucemia constituyeron los factores de riesgo prevalecientes.

  7. ''Cutie Pie,'' A portable radiation instrument

    International Nuclear Information System (INIS)

    Ballou, C.O.

    1947-01-01

    A portable beta and gamma radiation meter of exceedingly small dimensions and weight has been developed. User acceptance has been more enthusiastic than any previous instrument of its type. The circuit, using one Victoreen V-32 tube, is the simplest electronic circuit possible for radiation work and gives high sensitivity. Stability exceeds anything of comparable sensitivity which has come to our attention. The short term stability is due to a circuit which prevents emission before the cathode reaches operating temperature. Long term stability has been improved by evacuating the tube enclosure and switch. The complete, one unit instrument, weighs four pounds two ounces, and is carried with a pistol grip. Exclusive of chamber and handle, its dimensions are 3'' wide, 6 1/2'' long, and 5'' high. The case is formed of aluminum and is designed to give excellent visibility of the meter. Three ranges of approximately 50, 500 and 5000 mr/hr have been incorporated in the instruments. The instrument has been named ''Cutie Pie'' due to its diminutive size

  8. Estudio preliminar. Patologías digitales más frecuentes en el pie de la bailaora de flamencoe

    OpenAIRE

    José Manuel Castillo López; Joaquín Pérez Rendón; Cristina Algaba Guisado

    2010-01-01

    Este estudio tiene como objetivos, en primer lugar, dar a conocer las principales deformidades digitales de los pies, asociadas -por su alta incidencia- a la práctica profesional del baile flamenco femenino. Así como, poner de manifiesto la necesidad de llevar a cabo estudios de mayor magnitud para determinar si existe una relación estadísticamente significativa entre la práctica del baile flamenco con las deformidades y patologías podológicas descritas, y la importancia de la investigación e...

  9. Parámetros y valores genéticos para características de composición corporal, área de ojo del lomo y grasa dorsal medidos mediante ultrasonido en la raza Brahman

    Directory of Open Access Journals (Sweden)

    A. Jiménez

    2010-12-01

    Full Text Available El ganado Brahman en Colombia es el de mayor participación como raza pura paraproducción de carne, y tiene gran influencia en el ganado comercial. Hasta el momento,Asocebu ha realizado evaluaciones genéticas para características de crecimiento,pero aún no se han realizado para características de la canal. El objetivo de este trabajofue determinar parámetros genéticos (heredabilidades y correlaciones, y valores genéticos(DEP para área de ojo del lomo (AOL, grasa dorsal (GD, profundidad delmúsculo glúteo medio (PMGM y grasa del anca (GA. Fueron medidos por medio deultrasonido un total de 934 animales puros, hijos de 164 toros que se encontraban enun rango de edad de 15 a 18 meses. Para los análisis se crearon grupos contemporáneosteniendo en cuenta la época, el sexo y el manejo alimenticio. Se realizó un análisis univariadousando un modelo reproductor, teniendo en cuenta el grupo contemporáneo(animales del mismo sexo, de la misma época y en el mismo manejo alimenticio, laedad fue tomada como covariable y la finca fue incluida en el modelo. Las heredabilidadesfueron 0,37 ± 0,11; 0,29 ± 0,10; 0,26 ± 0,10 y 0,11 ± 0,09 para AOL, GD,PMGM y GA respectivamente. Las DEP para AOL variaron de -2,84 a 3,43; para GDde -0,372 a 0,235; para PMGM de -0,187 a 0,235, y para GD de -0,176 a 0,298. Lascorrelaciones genéticas fueron positivas y altas indicando que la selección por musculaturano afecta el grado de acabado. Este trabajo mostró que en ganado Brahman puroexiste variación genética para las características medidas por ultrasonido relacionadascon la canal, lo cual permitirá tenerlas en cuenta en el programa de mejoramientogenético de la raza Brahman en Colombia.

  10. Test requirement for PIE of HANARO irradiated fuel rod

    International Nuclear Information System (INIS)

    Lim, I. C.; Cho, Y. G.

    2000-06-01

    Since the first criticality of HANARO reached in Feb. of 1995, the rod type U 3 Si-A1 fuel imported from AECL has been used. From the under-water fuel inspection which has been conducted since 1997, a ballooning-rupture type abnormality was observed in several fuel rods. In order to find the root cause of this abnormality and to find the resolution, the post irradiation examination(PIE) was proposed as the best way. In this document, the information from the under-water inspection as well as the PIE requirements are described. Based on the information in this document, a detail test plan will be developed by the project team who shall conduct the PIE

  11. Code Analyses Supporting PIE of Weapons-Grade MOX Fuel

    International Nuclear Information System (INIS)

    Ott, Larry J.; Bevard, Bruce Balkcom; Spellman, Donald J.; McCoy, Kevin

    2010-01-01

    The U.S. Department of energy has decided to dispose of a portion of the nation's surplus weapons-grade plutonium by reconstituting it into mixed oxide (MOX) fuel and irradiating the fuel in commercial power reactors. Four lead test assemblies (LTAs) were manufactured with weapons-grade mixed oxide (WG-MOX) fuel and irradiated in the Catawba Nuclear Station Unit 1, to a maximum fuel rod burnup of ∼47.3 GWd/MTHM. As part of the fuel qualification process, five rods with varying burnups and initial plutonium contents were selected from one assembly and shipped to the Oak Ridge National Laboratory (ORNL) for hot cell examination. ORNL has provided analytical support for the post-irradiation examination (PIE) of these rods via extensive fuel performance modeling which has aided in instrument settings and PIE data interpretation. The results of these fuel performance simulations are compared in this paper with available PIE data.

  12. Solución Oportuna de Pie Plano

    OpenAIRE

    Espol; Tabares Cedeno, Maria Veronica; Ribadeneira Coloma, Betsy Evelyn; Zurita Aviles, Salomon Efrain

    2015-01-01

    Proponer una nueva técnica, donde se obtenga como beneficio la reparación definitiva de una lesion muy común como es el pie plano flexible y al mismo tiempo consolidar una empresa rentable y que genere valor ala sociedad el indice de prevalencia con diagnóstico de pie plano en el Ecuador es la especialidad de traumatología presentan este tipo de lesión. Guayaquil Magíster en Gerencia Hospitalaria

  13. Avaliação dos fatores interferentes na adesão ao tratamento do cliente portador de pé diabético Evaluación de los factores intervinientes en la adhesión al tratamiento del paciente con pie diabético Evaluation of interfering factors in treatment adherence of patients with diabetic foot conditions

    Directory of Open Access Journals (Sweden)

    Elizabeth Mesquita Melo

    2011-12-01

    Full Text Available A diabetes é uma doença crónica que exige adaptações na vida do cliente. O estudo objetivou avaliar a adesão do cliente portador de pé diabético ao tratamento. Estudo descritivo, quantitativo, realizado numa instituição especializada em diabetes, em Fortaleza-CE, com 45 clientes portadores de pé diabético. Os dados foram colhidos nos meses de fevereiro e março de 2009, expostos em gráficos e tabelas. O projeto foi aprovado pelo Comitê de ética em Pesquisa da Universidade de Fortaleza. Os clientes foram esclarecidos sobre o estudo, com participação voluntária. A maioria era do sexo masculino, na faixa etária de 50 a 79 anos e casados. Os principais fatores que interferem na adesão ao tratamento incluem: a baixa escolaridade, o nível socioeconómico, o déficit de conhecimento acerca da doença e a dificuldade de acesso ao serviço de saúde. A maioria dos clientes utilizava produtos caseiros para a cura da lesão, demonstrando crença em experiências anteriores. É fundamental que o cliente seja encorajado a assumir a responsabilidade de seu cuidado, enfatizando a necessidade das mudanças no estilo de vida.La diabetes es una enfermedad crónica que exige adaptaciones en la vida del paciente. El estudio tuvo como objetivo evaluar la adhesión del paciente con pie diabético al tratamiento. Se trató de un estudio descriptivo, cuantitativo, realizado en una institución especializada en diabetes, en Fortaleza-CE, con 45 pacientes con esta dolencia. Los datos fueron recolectados durante los meses de febrero a marzo de 2009 y fueron posteriormente expuestos en gráficos y tablas. El proyecto fue aprobado por el Comité de ética en Pesquisa de la Universidad de Fortaleza. A los pacientes, se les informó sobre el estudio, en el cual participaron de forma voluntaria. La mayoría era del sexo masculino, dentro de la franja etária de los 50 a los 79 años y estaban casados. Los principales factores que interfieren en la adhesi

  14. 49 CFR 40.385 - Who bears the burden of proof in a PIE proceeding?

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Who bears the burden of proof in a PIE proceeding... TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Public Interest Exclusions § 40.385 Who bears the burden of proof in a PIE proceeding? (a) As the proponent of issuing a PIE, the initiating official bears...

  15. Personalized Information Environments: Do Public Libraries Want a Slice of the PIE?

    Science.gov (United States)

    Worcester, Lea

    2003-01-01

    Discussion of personalized information environments (PIEs) focuses on library personalized interfaces. Describes academic library PIEs and commercial sites, such as Amazon.com that use personalization; explores the Public Library of Charlotte and Mecklenburg's personalized interface; and discusses opportunities and challenges PIEs offer public…

  16. La ortopodología en el pie de riesgo (1ª Parte)

    OpenAIRE

    Dorca Coll, Adelina; Céspedes Céspedes, Tomás; Concustell Gonfaus, Josep; Cuevas Gómez, Rafael; Sacristán Valero, Sergi

    1994-01-01

    Los autores definen por primera vez el concepto de 'pie de riesgo' y ofrecen diferentes alternativas podológicas para prevenir lesiones en el pie y en el supuesto de que estas lesiones estén establecidas, presentan tratamientos ortésicos que equilibren el pie y eviten mayores cambios degenerativos.

  17. 21 CFR 152.126 - Frozen cherry pie.

    Science.gov (United States)

    2010-04-01

    ... incorporating in a filling contained in a pastry shell mature, pitted, stemmed cherries that are fresh, frozen, and/or canned. The top of the pie may be open or it may be wholly or partly covered with pastry or other suitable topping. Filling, pastry, and topping components of the food consist of optional...

  18. Geometry and computation of Houndstooth (Pied-de-poule)

    NARCIS (Netherlands)

    Feijs, L.M.G.; Bosch, Robert; McKenna, Douglas; Sarhangi, Reza

    2012-01-01

    We apply a variety of geometric and computational tools to improve our understanding of the Houndstooth (Pied de poule) pattern. Although the pattern must have been known for centuries, it was made famous mostly by Christian Dior and is still frequently used in many variations. It is a

  19. Fitness costs of polygyny in female Pied Flycatchers Ficedula hypoleuca

    NARCIS (Netherlands)

    Both, C.

    2002-01-01

    Variance in mating systems can only be understood if the fitness consequences of the available options are known for both sexes. In Pied Flycatchers Ficedula hypoleuca it has for long been suggested that females pairing with already mated males pay a fitness cost, and it is still debated why females

  20. 9 CFR 381.158 - Poultry dinners (frozen) and pies.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Poultry dinners (frozen) and pies. 381... AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION POULTRY PRODUCTS INSPECTION REGULATIONS Definitions and Standards of Identity or...

  1. Shelf life of pie caps with biodegradable films as spacers

    Directory of Open Access Journals (Sweden)

    Daniela Verónica Escobar Gianni

    2013-01-01

    Full Text Available Commonly pie caps at market use polyethylene films as spacers between them. This paper studies the conventional spacers replacement with edible and biodegradable films made with whey protein isolate (WPI and potassium sorbate as a preservative. Besides facilitating the separation of pie caps, with this application is intended to increase their shelf life. The films made by the compression molding method were used as spacers in pie caps without preservative in their formula (A and with preservative (B and they were compared with conventional polyethylene spacers (C. During four months, monthly sensory, microbiological and physicochemical (humidity evaluations were done on the pie caps, together with humidity and solubility evaluations of the films. None of the samples showed microbiological or sensory deterioration. The sensory attributes showed no or slight difference in study time. Between samples the differences were minor: the best scores were for sample A in color, sample C in flavor, and samples B and C in texture and overall liking. The edible films have an interesting potential for this application, although studies in disguise the flavor of serum should be done.

  2. Nesting ecology of Pied Avocet Recurvirostra avosetta in Sfax salina ...

    African Journals Online (AJOL)

    In this paper we use the results of a one-year monitoring of nests in Sfax salina to provide information on its nesting parameters, in particular nesting phenology, colony size and hatching success. Our results show that Pied Avocets formed dense colonies at the beginning of the nesting season, but colony size decreased as ...

  3. Prevalencia y grado de pie plano según estado nutricional en niños escolares de las instituciones educativas Santa Isabel de Hungría y Santa Teresita de Jesús. Casma. 2010

    OpenAIRE

    Sánchez Reyna, Luis Fernando

    2016-01-01

    El objetivo del estudio fue establecer la prevalencia y grado de pie plano en relación al estado nutricional en niños escolares matriculados en las Instituciones Educativas Santa Isabel de Hungría y Santa Teresita de Jesús de la ciudad de Casma. Este estudio cuantitativo, descriptivo y transversal evaluó a 321 niños escolares durante el año 2010. Se clasificó en niños eutróficos, con sobrepeso y obesidad según las tablas del IMC para la edad de la OMS, y en niños con pie normal o pie plano de...

  4. Análisis de los factores influyentes en la prevalencia de las úlceras de pie en pacientes en hemodiálisis

    Directory of Open Access Journals (Sweden)

    María Jesús Lechuga Domínguez

    Full Text Available Resumen Introducción Los pacientes en tratamiento renal sustitutivo con terapia de hemodiálisis, tienen elevado riesgo de sufrir úlceras en los pies, debido a la presencia de numerosos factores de riesgo asociados. Objetivos El presente estudio, se plantea como objetivo principal establecer la prevalencia de úlceras en los pies, en los pacientes que realizan tratamiento con hemodiálisis en el Hospital San Rafael de A Coruña. Como objetivo secundario, valorar los factores de riesgo de ulceración del pie. Material y Método Se realiza un estudio descriptivo transversal, en el que incluyen a los 131 pacientes con insuficiencia renal crónica (IRC en tratamiento con hemodiálisis, que cumplen los criterios de inclusión. Se ha marcado como variable principal del estudio la presencia o ausencia de úlcera en el pie. Se valora el estado vascular, con la palpación de pulsos y con registro de sonido doppler de las arterias pedia y tibial posterior, además se realiza el cálculo del índice tobillo brazo (ITB. Se valora el estado neurológico, tras la exploración de la sensibilidad protectora con monofilamento y de la sensibilidad profunda con diapasón graduado. Resultados El 10,7% de los pacientes del estudio tienen úlcera activa en el pie. No se logra palpar pulso en la arteria pedia en un 43,5% de los pacientes y en la arteria tibial posterior en un 60% de la muestra estudiada. El 25% de los pacientes presenta un valor de ITB, por debajo de 0,90 y un 13,5% presenta arterias no compresibles. Presentan alteración de sensibilidad profunda un 48,9% de los pacientes y alteración de la sensibilidad protectora un 44,3%. Conclusión La prevención primaria a través de protocolos estandarizados de exploración del pie en las unidades de hemodiálisis, podrá minimizar la posibilidad de ulceraciones que comprometan la calidad de vida de los pacientes. Sistemáticamente habrá que realizar una valoración vascular, neurológica y de alteraciones

  5. Fernando González: caminando por su novela Viaje a pie

    Directory of Open Access Journals (Sweden)

    FRANCISCO LUIS GIRALDO GUTIÉRREZ

    2017-01-01

    Full Text Available Fernando González, ícono de la tradición literaria antioqueña, ha hecho que hoy en día las profundas y polémicas ideas sobre la realidad de su época lo presenten como un escritor con alta sensibilidad social, política y un constante renegar religioso. “Caminar” por la obra Viaje a pie , es precisamente eso: recorrer los senderos que él transitó en un tiempo. En el presente artículo se busca conocer la concepción que el autor tiene sobre la geografía, el amor, el desamor, la familia, la política y la religión, procurando así una caracterización del pensador envigadeño, la contextualización de los hechos y escenarios presentes en la obra referenciada.

  6. Proposed method for the hydraulic design of ski-jump energy dissipators in dam spillways considering the occurrence of scour holes downstream of the structure; Metodo propuesto para el diseno hidraulico de trampolines empleados como disipadores de energia en aliviaderos para presas, considerando la ocurrencia del cono de socavacion al pie del mismo

    Energy Technology Data Exchange (ETDEWEB)

    Pardo-Gomez, Rafael [Centro de Investigaciones Hidraulicas (Cuba)

    2008-04-15

    Ski-jump energy dissipators are widely used in hydraulic engineering because of their well-known effectiveness. Nevertheless, some uncertainty exits associated with the dimensions of the scour hole appearing downstream of the structure. This paper presents a new method for solving this problem. This method includes spillway stability checking as part of the design process and also stability checking of any other construction near the energy dissipation zone. [Spanish] Los disipadores de energia tipo trampolin tienen amplia utilizacion en la practica de la ingenieria hidraulica por su probada eficacia; sin embargo, su diseno esta sujeto a cierto grado de incertidumbre en cuanto a la prediccion de las dimensiones del cono de socavacion que habra de producirse aguas abajo de la estructura. En el presente trabajo se muestra un metodo novedoso, mediante el cual el autor soluciona el aspecto antes referido, toda vez que se incluye como parte del proceso de diseno la comprobacion de la estabilidad del propio aliviadero o de cualquier otra obra cercana a la zona de disipacion de energia.

  7. PIE of test assembly of Qinshan nuclear power plant

    International Nuclear Information System (INIS)

    Ran, M.; Yan, J.; Wang, S.

    2000-01-01

    The small dimensional test fuel assembly (3x3-2) for the Qinshan Nuclear Power Plant was irradiated up to 25.7 Gwd/tU in the in-pile loop (15.5 Mpa,320 C) in Heavy Water Research Reactor (HWRR), CIAE, at simulative condition to Qinshan PWR normal and short time overpower operation for verifying the design, technology, and material properties of the fuel assembly. Comprehensive post-irradiation examination (PIE) including dimension measurement, gamma scanning, eddy current test, X ray, radiography, measurement of fission gas release, and quantitative metallography etc. were performed. PIE results show that the diameter of the fuel rods changed, ridges appeared on the cladding, pellets swelled, and the rate of fission gas release was higher than what we expected. The results would be an important basis for further improvement of design, technology and material properties for Qinshan PWR assembly. (author)

  8. Development of PIE techniques for irradiated LWR pressure vessel steels

    International Nuclear Information System (INIS)

    Nishi, Masahiro; Kizaki, Minoru; Sukegawa, Tomohide

    1999-01-01

    For the evaluation of safety and integrity of light water reactors (LWRs), various post irradiation examinations (PIEs) of reactor pressure vessel (RPV) steels and fuel claddings have been carried out in the Research Hot Laboratory (RHL). In recent years, the instrumented Charpy impact testing machine was remodeled aiming at the improvement of accuracy and reliability. By this remodeling, absorbed energy and other useful information on impact properties can be delivered from the force-displacement curve for the evaluation of neutron irradiation embrittlement behavior of LWR-RPV steels at one-time striking. In addition, two advanced PIE technologies are now under development. One is the remote machining of mechanical test pieces from actual irradiated pressure vessel steels. The other is development of low-cycle and high-cycle fatigue test technology in order to clarify the post-irradiation fatigue characteristics of structural and fuel cladding materials. (author)

  9. Development, irradiation testing and PIE of UMo fuel at AECL

    International Nuclear Information System (INIS)

    Sears, D.F.

    2005-01-01

    This paper reviews recent U-Mo dispersion fuel development, irradiation testing and postirradiation examination (PIE) activities at AECL. Low-enriched uranium fuel alloys and powders have been fabricated at Chalk River Labs, with compositions ranging from U-7Mo to U-10Mo. The bulk alloys and powders were characterized using optical and scanning electron microscopy, chemical analysis, X-ray diffraction and neutron diffraction analysis. The analyses confirmed that the powders were of high quality, and in the desired gamma phase. Subsequently, kilogram quantities of DU-Mo and LEU-Mo powder have been manufactured for commercial customers. Mini-elements have been fabricated with LEU-7Mo and LEU-10Mo dispersed in aluminum, with a nominal loading of 4.5 gU/cm 3 . These have been irradiated in the NRU reactor at linear powers up to 100 kW/m. The mini-elements achieved 60 atom% 235 U burnup in 2004 March, and the irradiation is continuing to a planned discharge burnup of 80 atom% 235 U. Interim PIE has been conducted on mini-elements that were removed after 20 atom% 235 U burnup. The PIE results are presented in this paper. (author)

  10. Estudio piloto del modelo técnico de ejecución del pitch a captura de pies en gimnasia acrobática. (A pilot study of technical model during a simulated toe pitch to catch in gymnastics acrobatics.

    Directory of Open Access Journals (Sweden)

    Juan Antonio León-Prados

    2010-04-01

    Full Text Available En Gimnasia Acrobática (GA el Toe Pitch to Catch (TPC es una acción técnica muy usual, lo que motiva la necesidad de proporcionar un modelo técnico del movimiento que permita facilitar la compresión de los factores relacionados con su ejecución. Se analizaron 12 ejecuciones sin penalizaciones técnicas realizadas por una pareja mixta de GA utilizando técnicas de fotogrametría y dinamometría. Para el análisis se dividió el movimiento en tres fases: Impulsión, Vuelo y Recepción. Los resultados indicaron que el valor máximo de fuerza en la Fase de Impulsión fue de 2,67 ± 0,06 BW (PC: Peso Corporal, BW: Body Weigth mientras que en la de Recepción fue de 2,78 ± 0,30 PC: Peso Corporal. En el modelo técnico individual analizado se destaca cómo en la Fase de Impulsión es más importante optimizar el impulso aplicado que la fuerza máxima. Durante la Fase de Vuelo, sobresale la alta reproducibilidad en los intentos satisfactorios de la altura alcanzada por el Top para facilitar su posterior recepción. Finalmente durante la Fase de Recepción, se destaca la acción de frenado del Base con el fin de minimizar las fuerzas de reacción verticales del suelo en los movimientos de recepción del Top.AbstractIn acrobatic gymnastics Toe Pitch to Catch (TPC is one of the most traditional skill. The aim of the study was to provide a technical model of the skill to facilitate the understanding of the principal factors associated with the execution. In order to elaborate the model, 12 tryouts without technical deductions performed by a mixed pair of gymnasts were analyzed using techniques of photogrammetric and dynamometry. The movement was divided into three different phases for analysing purposes: Propulsion, Flight and Reception. Results indicated that maximum value of the force during the Propulsion Phase was 2,67 ± 0,06 BW, whereas during the Reception Phase the value obtained was 2,78 ± 0,30 BW. In the technical model analyzed highlights

  11. Pie technique of LWR fuel cladding fracture toughness test

    International Nuclear Information System (INIS)

    Endo, Shinya; Usami, Koji; Nakata, Masahito; Fukuda, Takuji; Numata, Masami; Kizaki, Minoru; Nishino, Yasuharu

    2006-01-01

    Remote-handling techniques were developed by cooperative research between the Department of Hot Laboratories in the Japan Atomic Energy Research Institute (JAERI) and the Nuclear Fuel Industries Ltd. (NFI) for evaluating the fracture toughness on irradiated LWR fuel cladding. The developed techniques, sample machining by using the electrical discharge machine (EDM), pre-cracking by fatigue tester, sample assembling to the compact tension (CT) shaped test fixture gave a satisfied result for a fracture toughness test developed by NFL. And post-irradiation examination (PIE) using the remote-handling techniques were carried out to evaluate the fracture toughness on BWR spent fuel cladding in the Waste Safety Testing Facility (WASTEF). (author)

  12. PIE Report on the KOMO-3 Irradiation Test Fuels

    International Nuclear Information System (INIS)

    Park, Jong Man; Ryu, H. J.; Yang, J. H.

    2009-04-01

    In the KOMO-3, in-reactor irradiation test had been performed for 12 kinds of dispersed U-Mo fuel rods, a multi wire fuel rod and a tube fuel rod. In this report we described the PIE results on the KOMO-3 irradiation test fuels. The interaction layer thickness between fuel particle and matrix could be reduced by using a large size U-Mo fuel particle or introducing Al-Si matrix or adding the third element in the U-Mo particle. Monolithic fuel rod of multi-wire or tube fuel was also effective in reducing the interaction layer thickness

  13. The pied piper of Hamelin: Exploring the story

    Directory of Open Access Journals (Sweden)

    Leila Mury Bergmann

    2008-12-01

    Full Text Available This article’s goal is to explore the story of The Pied Piper of Hamelin. In order to do so, social aspects of childhood in the (probable time when the story was created are presented, as well as some curiosities about the text. Furthermore, this paper brings a personal statement (by the authors of a storytelling activity in a public school nursery in Porto Alegre, based upon the version of the book The Pied Piper of Hamelin, by Tatiana Belinky. After some questions and informal conversation about the tale, the children’s verbal expositions were analyzed. The research brings, as a theoretical background, contributions of studies from authors connected, mainly, to the field of Children’s Literature and Education. It brought the conclusion that the piper’s story motivated representative interventions, since during the storytelling activity children used typical aspects of their culture and also showed their dominium of temporal arrangement of the text’s events, as well as their peculiar creativity – according to their age – of recreating in the situation of the so-called make-believe.

  14. Magnetic Resonance Imaging: A Tool for Pork Pie Development

    Science.gov (United States)

    Gaunt, Adam P.; Morris, Robert H.; Newton, Michael I.

    2013-01-01

    The traditional British pork pie consists of roughly chopped pork cooked in a hot water pastry crust. Due to shrinkage of the meat during cooking, the gap formed around the meat is usually sealed using a gelatin based jelly to exclude air and thus help to preserve the pie. The properties of the jelly are such that it will ingress into the pastry crust causing undesirable softening. The jelly is traditionally produced by simmering pig trotters with seasoning for several hours. In this work we demonstrate the potential of magnetic resonance imaging (MRI) as a tool for investigating the conditions required for producing jellies with different properties and present two examples of this use. Firstly we demonstrate that MRI can determine the ability of water to diffuse through the jelly which is critical in minimizing the amount of moisture moving from the jelly to the crust. Secondly, the impact of jelly temperature on the penetration length into the crust is investigated. These examples highlight the power of MRI as a tool for food assessment. PMID:28239124

  15. Introducing a Framework for Physics Innovation and Entrepreneurship (PIE) Education

    Science.gov (United States)

    Roughani, Bahram

    A desired outcome for Physics Innovation and Entrepreneurship (PIE) education is preparing physics majors with an innovative and entrepreneurial mindset who are capable of opportunity recognition and adept in leveraging physics knowledge to address specific needs. Physics as a discipline is well-recognized to prepare students who become problem solvers and critical thinkers, gifted in dealing with abstract ideas and ambiguities in the context of complex and real-world problems. These characteristics when enhanced through appropriate combinations of curricular, co-curricular, and extra-curricular programs can prepare physics majors for careers and future challenges that may involve translating physics knowledge into useful products and services either as part of a technical team within an organization or through startups. A viable PIE education model prepares graduates for various career paths in addition to the traditional options such as pursuing graduate studies or becoming a science teacher. Having a well-defined ``third option'' for physics will benefit the robustness of the physics discipline through recruitment and retention of prospective students who in principle are interested in physics as a subject, but in practice they may overlook physics as their preferred major primarily because they are uncertain about a viable career path based on an undergraduate physics education. The ''Pathways to Innovation'' at Loyola is established based on the program developed by VentureWell and Epicenter (NSF Supported).

  16. Proceedings of 2005 JAEA-KAERI joint seminar on advanced irradiation and PIE technologies

    International Nuclear Information System (INIS)

    2006-05-01

    In this seminar, total participants of over 100 were jointed from JAEA, KAERI, Hanyang University, Chungnam National University, Kyung Hee University, Oarai Branch of Institute for Materials Research (IMR) of Tohoku University, Nippon Nuclear Fuel Development Co., Ltd., Nuclear Development Corporation and others. The technical development and experimental data on the irradiation test and PIE were aggressively discussed in this seminar. Contributed presentations were 35 in three sessions; Current status and future program on irradiation test and PIE (10 presentations), Development of irradiation and PIE technologies (15 presentations) and Evaluation of irradiation and PIE data (10 presentations). Development of instrumented capsule technologies for HANARO irradiation, current PIE activities in each hot laboratory of both countries, development of irradiation capsules in JMTR for the Irradiation Assisted Stress Corrosion Cracking (IASCC) study, development of irradiation and PIE techniques for the safety research on the high burnup fuel, utilization plan of JOYO and development of MOX fuel containing americium have been widely noticed as topic items on irradiation and PIE technologies. This proceedings is containing papers presented in the 2005 JAEA-KAERI Joint Seminar. It also indicates the current status of the aggressive information exchange activity on two fields of irradiation test and PIE technologies between JAEA and KAERI under the Arrangement for the Implementation of Cooperative Research Program mentioned above. The 35 of the presented papers are indexed individually. (J.P.N.)

  17. Atritis gotosa como causa de pie de riesgo

    OpenAIRE

    Ortega-Avila, Ana Belén; Fernández Torres, Raúl; Agüera Jiménez, David

    2016-01-01

    INTRODUCCIÓN: La gota es una manifestación común de la artritis, cuya inflamación se debe al depóstido de cristales de uratao monosódico en articulaciones y tejidos blandos por un aumento de ácido úrico en sangre y su padecimiento muestra una relación creciente con la edad. OBJETIVOS: Analizar las características fisiopatológicas de la artritis gotosa en el pie así como justificar la repercusión negativa que tiene su padecimiento en la calidad de vida de la población basándose en la simple af...

  18. Enlarging the Societal Pie Through Wise Legislation: A Psychological Perspective.

    Science.gov (United States)

    Baron, Jonathan; Bazerman, Max H; Shonk, Katherine

    2006-06-01

    We offer a psychological perspective to explain the failure of governments to create near-Pareto improvements. Our tools for analyzing these failures reflect the difficulties people have trading small losses for large gains: the fixed-pie approach to negotiations, the omission bias and status quo bias, parochialism and dysfunctional competition, and the neglect of secondary effects. We examine the role of human judgment in the failure to find wise trade-offs by discussing diverse applications of citizen and government decision making, including AIDS treatment, organ-donation systems, endangered-species protection, subsidies, and free trade. Our overall goal is to offer a psychological approach for understanding suboptimality in government decision making. © 2006 Association for Psychological Science.

  19. Structural Conservation and Functional Diversity of the Poxvirus Immune Evasion (PIE) Domain Superfamily.

    Science.gov (United States)

    Nelson, Christopher A; Epperson, Megan L; Singh, Sukrit; Elliott, Jabari I; Fremont, Daved H

    2015-08-28

    Poxviruses encode a broad array of proteins that serve to undermine host immune defenses. Structural analysis of four of these seemingly unrelated proteins revealed the recurrent use of a conserved beta-sandwich fold that has not been observed in any eukaryotic or prokaryotic protein. Herein we propose to call this unique structural scaffolding the PIE (Poxvirus Immune Evasion) domain. PIE domain containing proteins are abundant in chordopoxvirinae, with our analysis identifying 20 likely PIE subfamilies among 33 representative genomes spanning 7 genera. For example, cowpox strain Brighton Red appears to encode 10 different PIEs: vCCI, A41, C8, M2, T4 (CPVX203), and the SECRET proteins CrmB, CrmD, SCP-1, SCP-2, and SCP-3. Characterized PIE proteins all appear to be nonessential for virus replication, and all contain signal peptides for targeting to the secretory pathway. The PIE subfamilies differ primarily in the number, size, and location of structural embellishments to the beta-sandwich core that confer unique functional specificities. Reported ligands include chemokines, GM-CSF, IL-2, MHC class I, and glycosaminoglycans. We expect that the list of ligands and receptors engaged by the PIE domain will grow as we come to better understand how this versatile structural architecture can be tailored to manipulate host responses to infection.

  20. Agenesis of the dorsal pancreas

    Science.gov (United States)

    Schnedl, Wolfgang J; Piswanger-Soelkner, Claudia; Wallner, Sandra J; Krause, Robert; Lipp, Rainer W

    2009-01-01

    During the last 100 years in medical literature, there are only 54 reports, including the report of Pasaoglu et al (World J Gastroenterol 2008; 14: 2915-2916), with clinical descriptions of agenesis of the dorsal pancreas in humans. Agenesis of the dorsal pancreas, a rare congenital pancreatic malformation, is associated with some other medical conditions such as hyperglycemia, abdominal pain, pancreatitis and a few other diseases. In approximately 50% of reported patients with this congenital malformation, hyperglycemia was demonstrated. Evaluation of hyperglycemia and diabetes mellitus in all patients with agenesis of the dorsal pancreas including description of fasting blood glucose, oral glucose tolerance test, glycated hemoglobin and medical treatment would be a future goal. Since autosomal dominant transmission has been suggested in single families, more family studies including imaging technologies with demonstration of the pancreatic duct system are needed for evaluation of this disease. With this letter to the editor, we aim to increase available information for the better understanding of this rare disease. PMID:19140241

  1. Estratificación de riesgo en pie diabético Risk stratification in diabetic foot

    Directory of Open Access Journals (Sweden)

    Héctor González de la Torre

    2010-12-01

    Full Text Available El pie diabético es una complicación crónica de la diabetes mellitus y constituye una problemática sanitaria al conllevar un enorme gasto económico a los servicios sanitarios y provocar a las personas que lo padecen y a su entorno familiar enormes repercusiones emocionales. La educación sanitaria en el cuidado de los pies de los diabéticos, así como la cuantificación del riesgo son aspectos que el enfermero debe incorporar en los planes de cuidados de los pacientes diabéticos. La detección de los posibles factores de riesgo es un paso previo imprescindible para estos cometidos. Este estudio tiene como finalidad analizar la presencia de determinados factores de riesgo en pie diabético en la población diabética del Centro de Salud de Triana, con el objetivo de poder realizar, así, una estratificación del riesgo. Para ello, se optó por la realización de un estudio observacional descriptivo. La muestra analizada estaba constituida por 96 sujetos diabéticos pertenecientes a dicho centro de salud. Para la recogida de datos se utilizó un sistema de tres niveles consistente en entrevista, exploración física y consulta de registros disponibles (a través de las historias clínicas de los sujetos. Los datos se registraron en un formulario de recogida de datos para pie diabético. Se determinó la existencia de factores de riesgo, analizando las relaciones entre éstos y permitiendo la estratificación del riesgo en la población estudiada.The diabetic foot is a chronic complication of diabetes mellitus and constitutes a sanitary problem which causes not only enormous expenses for the sanitary system but also provokes emotional repercussions for the person who suffers the illness and for the family. The sanitary education in taking care of the feet of diabetics and the identification of the health risk are both aspects that the nurse must include in the healthcare planning of diabetic patients. The detection of the possible risk

  2. The causal pie model: an epidemiological method applied to evolutionary biology and ecology.

    Science.gov (United States)

    Wensink, Maarten; Westendorp, Rudi G J; Baudisch, Annette

    2014-05-01

    A general concept for thinking about causality facilitates swift comprehension of results, and the vocabulary that belongs to the concept is instrumental in cross-disciplinary communication. The causal pie model has fulfilled this role in epidemiology and could be of similar value in evolutionary biology and ecology. In the causal pie model, outcomes result from sufficient causes. Each sufficient cause is made up of a "causal pie" of "component causes". Several different causal pies may exist for the same outcome. If and only if all component causes of a sufficient cause are present, that is, a causal pie is complete, does the outcome occur. The effect of a component cause hence depends on the presence of the other component causes that constitute some causal pie. Because all component causes are equally and fully causative for the outcome, the sum of causes for some outcome exceeds 100%. The causal pie model provides a way of thinking that maps into a number of recurrent themes in evolutionary biology and ecology: It charts when component causes have an effect and are subject to natural selection, and how component causes affect selection on other component causes; which partitions of outcomes with respect to causes are feasible and useful; and how to view the composition of a(n apparently homogeneous) population. The diversity of specific results that is directly understood from the causal pie model is a test for both the validity and the applicability of the model. The causal pie model provides a common language in which results across disciplines can be communicated and serves as a template along which future causal analyses can be made.

  3. Current activities in development of PIE techniques in JMTR hot laboratory

    International Nuclear Information System (INIS)

    Ishii, Toshimitsu; Ohmi, Masao; Shimizu, Michio; Kaji, Yoshiyuki; Ueno, Fumiyoshi

    2006-01-01

    A wide variety of post-irradiation examinations (PIEs) for research and development of nuclear fuels and materials to be utilized in nuclear field has been carried out since 1971 in three kinds of β-γ hot cells; concrete, lead and steel cells in the JMTR Hot Laboratory (JMTR HL) associated with the Japan Materials Testing Reactor (JMTR). In addition to PIEs, the re-capsuling work including re-instrumentation was also conducted for the power ramping tests of the irradiated LWR fuels using Boiling Water Capsule (BOCA). Recently, new PIE techniques are required for the advanced irradiation studies. In this paper, the irradiation assisted stress corrosion cracking (IASCC) growth test technique of irradiated in-core structural materials and the remote operation technique of the atomic force microscope (AFM) are described as JMTR HL's current activities in the development of new PIE techniques. (author)

  4. La enfermedad de manos, pies y boca (Hand, Foot, and Mouth Disease)

    Centers for Disease Control (CDC) Podcasts

    La enfermedad de manos, pies y boca es una enfermedad contagiosa que afecta principalmente a niños menores de cinco años. En este podcast, la doctora Eileen Schneider habla de los síntomas de la enfermedad de manos, pies y boca, cómo se propaga y cómo protegerse y proteger a sus hijos para que no se infecten con el virus.

  5. Geophysical evidence for an extensive Pie de Palo Complex mafic-ultramafic belt, San Juan, Argentina

    Science.gov (United States)

    Chernicoff, Carlos J.; Vujovich, Graciela I.; van Staal, Cees R.

    2009-12-01

    The recent completion of a high-resolution aeromagnetic survey over the Pie de Palo uplift of the western Sierras Pampeanas has revealed an area of large magnetic anomalies associated with the Pie de Palo Complex. The Las Pirquitas thrust, which has transported and uplifted the Pie de Palo Complex, is recognized for at least 30 km in a roughly NE direction along the western boundary of the Pie de Palo Complex, beyond its limited outcrop. The type of sediments of the Caucete Group in the footwall of the Las Pirquitas thrust, which are regarded as the leading edge of the Precordillera terrane, are associated with much less pronounced magnetic anomalies. In addition, a conspicuous, NNE trending, broad magnetic high stands out in the survey, several kilometers to the east of the main outcrops of the Pie de Palo Complex; this broad magnetic anomaly bisects the Pie de Palo basement block, and continues further south at least as far as 32°S, the southern boundary of the latest aeromagnetic survey. This magnetic anomaly is interpreted to represent a structure corresponding to the Grenvillian Precordillera-Pie de Palo tectonic boundary zone, and would comprise the buried largest part of the mafic-ultramafic belt. The geophysical model of the magnetic data indicates that the boundary zone dips to the east, possibly suggesting the existence of a set of synthetic east dipping, west-verging thrusts, of which only one major structure (Las Pirquitas thrust) is exposed; the possibility of other slivers of upthrust boundary zone material cannot be excluded. It is considered that the Pie de Palo Complex represents a small sliver upthrust from the unexposed boundary zone material (containing highly magnetic mafic-ultramafic rocks). The east-dipping, west verging structures associated with the Pie de Palo Complex are suggested to represent an Ordovician reactivation of a Grenvillian suture zone developed when the Precordillera basement and Pie de Palo terrane docked; this

  6. Cuento: El naufragio del circo

    Directory of Open Access Journals (Sweden)

    Guillermo Hoyos Trujillo

    1967-12-01

    Full Text Available El barco se agitaba al vaivén de las olas, como si estuviera bailando una danza macabra; sus cuadernas crujían y el piloto conservaba difícilmente el rumbo. El capitán y el ingeniero, sosteniéndose de pies con precario equilibrio sobre la bodega de proa, trataban de aquietar inútilmente al arisco pasaje integrado por los artistas, técnicos y trabajadores del Circo Recore.

  7. DORSAL ROOT REGENERATION INTO TRANSPLANTS OF DORSAL OR VENTRAL HALF OF EMBRYONIC SPINAL CORD

    OpenAIRE

    Ohta, Tohru; Itoh, Yasunobu; Tessler, Alan; Mizoi, Kazuo

    2009-01-01

    Adult cut dorsal root axons regenerate into the transplants of embryonic spinal cord (ESC) and form functional synapses within the transplants. It is unknown whether the growth is specific to transplants of dorsal half of ESC, a normal target of most dorsal root axons, or whether it is due to properties shared by transplants of ventral half of ESC. We used calcitonin gene-related peptide (CGRP) immunohistochemistry to label to the subpopulations of regenerated adult dorsal root axons, quantit...

  8. Liposarcome dorsal: aspect clinique rare

    Science.gov (United States)

    Agbessi, Odry; Arrob, Adil; Fiqhi, Kamal; Khalfi, Lahcen; Nassih, Mohammed; El Khatib, Karim

    2015-01-01

    Décrit la première fois par Virchow en 1860, le liposarcome est une tumeur mésenchymateuse rare. Cette rareté est relative car les liposarcomes représentent quand même 14 à 18% de l'ensemble des tumeurs malignes des parties molles et ils constituent le plus fréquent des sarcomes des parties molles. Pour la majorité des auteurs, il ne se développerait jamais sur un lipome ou une lipomatose préexistant. Nous rapportons un cas de volumineux liposarcome de la face dorsale du tronc. L'histoire de la maladie, l'aspect clinique inhabituel « de tumeur dans tumeur », l'aspect de la pièce opératoire nous fait évoquer la possibilité de la transformation maligne d'un lipome bénin préexistant. PMID:26113914

  9. Dorsal skinfold chamber models in mice

    Directory of Open Access Journals (Sweden)

    Schreiter, Jeannine

    2017-07-01

    Full Text Available Background/purpose: The use of dorsal skinfold chamber models has substantially improved the understanding of micro-vascularisation in pathophysiology over the last eight decades. It allows pathophysiological studies of vascularisation over a continuous period of time. The dorsal skinfold chamber is an attractive technique for monitoring the vascularisation of autologous or allogenic transplants, wound healing, tumorigenesis and compatibility of biomaterial implants. To further reduce the animals’ discomfort while carrying the dorsal skinfold chamber, we developed a smaller chamber (the Leipzig Dorsal Skinfold Chamber and summarized the commercial available chamber models. In addition we compared our model to the common chamber. Methods: The Leipzig Dorsal Skinfold Chamber was applied to female mice with a mean weight of 22 g. Angiogenesis within the dorsal skinfold chamber was evaluated after injection of fluorescein isothiocyanate dextran with an Axio Scope microscope. The mean vessel density within the dorsal skinfold chamber was assessed over a period of 21 days at five different time points. The gained data were compared to previous results using a bigger and heavier dorsal skinfold model in mice. A PubMed and a patent search were performed and all papers related to “dorsal skinfold chamber” from 1 of January 2006 to 31 of December 2015 were evaluated regarding the dorsal skinfold chamber models and their technical improvements. The main models are described and compared to our titanium Leipzig Dorsal Skinfold Chamber model.Results: The Leipzig Dorsal Skinfold Chamber fulfils all requirements of continuous models known from previous chamber models while reducing irritation to the mice. Five different chamber models have been identified showing substantial regional diversity. The newly elaborated titanium dorsal skinfold chamber may replace the pre-existing titanium chamber model used in Germany so far, as it is smaller and lighter

  10. Great tit and pied flycatcher populations on the territory of radioactive trail in the eastern Urals

    International Nuclear Information System (INIS)

    Lebedeva, N.V.

    1994-01-01

    The purpose of this preliminary study was to evaluate the prospects for using populations of the great tit (Parus major) and the pied flycatcher (Ficedula hypoleuca) in ecological monitoring of territories contaminated with radionuclides. Studies were performed in the summer of 1992 in birch forests of the Southern Urals. Artificial nesting sites (log houses) located 1.5 m above the ground were distributed over territories of two test plots: 30 log houses on the contaminated plot and 60 on the control plot (contamination with Sr-90 1.5 and 2 · 10 -3 mCi/m 2 , respectively). The nesting success in the great tit was similar on both plots, whereas that in the pied flycatcher was significantly greater on the control plot (in a open-quotes cleanclose quotes forest). Pied flycatchers build their nests out of highly radioactive materials, whereas great tits use nonradioactive or weakly emitting materials. Hence, pied flycatcher's nestlings receive a significant radiation dose from components of the nest: From the moment of egg laying, this dose amounts to 0.5 rem. The pied flycatcher can be used as an indicator of radioactive contamination. This species is more sensitive than the great tit, which has been successfully used as an indicator for monitoring the industrial air pollution

  11. Estudio preliminar. Patologías digitales más frecuentes en el pie de la bailaora de flamencoe

    Directory of Open Access Journals (Sweden)

    José Manuel Castillo López

    2010-05-01

    Full Text Available Este estudio tiene como objetivos, en primer lugar, dar a conocer las principales deformidades digitales de los pies, asociadas -por su alta incidencia- a la práctica profesional del baile flamenco femenino. Así como, poner de manifiesto la necesidad de llevar a cabo estudios de mayor magnitud para determinar si existe una relación estadísticamente significativa entre la práctica del baile flamenco con las deformidades y patologías podológicas descritas, y la importancia de la investigación en el campo de la medicina del deporte, y de la ortopodología y biomecánica en pos de hallar tratamientos preventivos y/o paliativos en su caso.En este estudio epidemiológico preliminar, llevado a cabo con la colaboración de la Universidad de Sevilla-Área Clínica de Podología y Departamento de Podología- Agencia Andaluza para el Desarrollo del Flamenco, Fundación Cristina Heeren de Arte Flamenco, Centro de Baile Flamenco Ana Moya, y el Centro de Investigación de Flamenco Telethusa, se han evaluado a 28 bailaoras profesionales activas en la provincia de Sevilla, con una actividad mínima de 20h semanales. En dicha muestra se han determinado las patologías podológicas presentes, sintomatología, hábitos de uso de calzado específico, y hábitos podológicos. Los resultados muestran una alta incidencia de patologías digitales como el H.A.V. (juanetes, dedos en garra, y onicopatías.

  12. Description of the PIE facility for research reactors irradiated fuels in CNEA

    International Nuclear Information System (INIS)

    Bisca, A.; Coronel, R.; Homberger, V.; Quinteros, A.; Ratner, M.

    2002-01-01

    The PIE Facility (LAPEP), located at the Ezeiza Atomic Center (CAE), was designed to carry out destructive and non-destructive post-irradiation examinations (PIE) on research and power reactor spent fuels, reactor internals and other irradiated materials, and to perform studies related with: Station lifetime extension; Fuel performance; Development of new fuels; and Failures and determination of their causes. LAPEP is a relevant facility where research and development can be carried out. It is worth mentioning that in this facility the PIE corresponding to the Surveillance Program for the Atucha I Nuclear Power Plant (CNA-1) were successfully performed. Materials testing during the CNA-1 repair and the study of failures in fuel element plugs of the Embalse Nuclear Power Plant (CNE) were also performed. (author)

  13. Lo que está bajo nuestros pies

    Directory of Open Access Journals (Sweden)

    Paula C. de A. Maria Castelhano

    2011-01-01

    Full Text Available En este trabajo se pretende demostrar cómo el estudio del comportamiento de las ondas sísmicas llevó a la construcción del modelo físico de la estructura interna de la Tierra en diferentes capas concéntricas. Los modelos analógicos en educación de la ciencias son instrumentos esenciales que hacen los conocimientos científicos más comprensible, facilitando la comprensión de conceptos abstractos y favoreciendo así el interés de los estudiantes.

  14. Evaluación integral de la sensibilidad en los pies de las personas con diabetes mellitus tipo 2

    Directory of Open Access Journals (Sweden)

    Valentina Rivas Acuña

    2017-01-01

    Full Text Available Introducción: Actualmente la diabetes mellitus tipo 2 es considerada una epidemia en el mundo, es uno de los problemas de mayor trascendencia, por su alta prevalencia como por su enorme repercusión social y económica, por tal motivo el propósito del estudio fue evaluar de manera integral la sensibilidad en los pies de las personas con diabetes mellitus tipo 2, de Villahermosa, Tabasco, México. Materiales y Métodos: El diseño fue descriptivo correlacional, la muestra fue de 198 personas. Se utilizó el Test del Michigan Neuropathy Screening con monofilamento de Semme Weinstein, Diapasón, temperatura frío/calor y reflejo Aquileo. Resultados y Discusión: El sexo femenino predominó con un 70.2% y el 29.8% hombres, el promedio de edad fue 56.44 años y 12.34 años promedio con la enfermedad. El 46% registró síntomas neuropáticos moderados, 26.3% graves; el 65.7% riesgo de neuropatía positiva (40.9% mujeres y 24.8% hombres, 41.1% con pérdida de sensibilidad moderada y 29.3% sensibilidad normal; el 74.7% tiene un control glucémico deficiente. Los factores de riesgo detectados con mayor prevalencia fueron helomas, hiperqueratosis y deformidades. Conclusiones: Existe una correlación significativa entre la pérdida de la sensibilidad con los años con la enfermedad, con la hiperglucemia y síntomas de neuropatía, la pérdida de sensibilidad en mujeres es de moderada a grave y en los hombres la pérdida de la sensibilidad es moderada. Cómo citar este artículo: Rivas V, Mateo Y, García H, Martínez A, Magaña M, Carrillo R.  Evaluación integral de la sensibilidad en los pies de las personas con diabetes mellitus tipo 2. Rev Cuid. 2017; 8(1:1423-32. http://dx.doi.org/10.15649/cuidarte.v8i1.348

  15. Fracturas Fisarias Salter-Harris VI de Tobillo y Pie. [Salter-Harris VI fractures of the foot and ankle.

    Directory of Open Access Journals (Sweden)

    Julio Javier Masquijo

    2015-06-01

    Full Text Available Introducción Las fracturas Salter-Harris VI (SHVI son lesiones que se caracterizan por presentar ablación del anillo pericondral. Son infrecuentes en niños pero potencialmente devastadoras. El objetivo de este estudio fue evaluar el mecanismo de producción, el tratamiento y los resultados funcionales de estas lesiones localizadas en el pie y el tobillo. Material y métodos Se analizaron retrospectivamente todos los pacientes con lesiones SHVI de tobillo y pie tratadas entre Enero de 2010 y Enero de 2013. Se documentaron datos demográficos, clasificación, mecanismo de lesión, tipo de lesiones asociadas y número de cirugías que requirieron. Los pacientes fueron evaluados funcionalmente con el score de AOFAS y radiográficamente para determinar la viabilidad de la fisis, acortamiento del miembro o deformidad angular. Resultados Se analizaron 5 fracturas en 4 pacientes (3 masculinos y 1 femenino. La edad promedio al momento de la lesión fue de 7.5 años (rango, 6  a 10 años. El seguimiento promedio fue de 26.2 meses (rango, 12 - 37 meses. De acuerdo a la subclasificación de Peterson 3 pertenecían al grupo A, 1 al B y 1 al C. 3 lesiones se produjeron como consecuencia de accidentes de moto y 2 por auto versus peatón. Todos los casos se acompañaron de pérdida de sustancia, el 75% presentaba lesiones en más de un hueso y el 50% lesiones tendinosas asociadas. Cada paciente requirió un promedio de 3.2 cirugías (rango, 2 a 5. El score AOFAS promedio fue de 79.8 puntos (rango, 62 – 100 puntos. Radiográficamente, solo el 40% de las fisis afectadas permanecían viables al último control. Conclusión Las fracturas SHVI se acompañan de una gran variedad de lesiones asociadas, requieren múltiples cirugías y suelen producir un cierre precoz de la fisis y algún grado de discapacidad.  Se requieren medidas de prevención para evitar la exposición de los niños a este tipo de lesiones. El tratamiento temprano es fundamental para

  16. 49 CFR 40.403 - Must a service agent notify its clients when the Department issues a PIE?

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Must a service agent notify its clients when the... Must a service agent notify its clients when the Department issues a PIE? (a) As a service agent, if... clients, in writing, about the issuance, scope, duration, and effect of the PIE. You may meet this...

  17. Conocimientos y conductas de los pacientes con diabetes mellitus sobre el pie diabético Knowledge and behaviors of the patients with diabetes mellitus in relation to the diabetic foot

    Directory of Open Access Journals (Sweden)

    Ulises de Jesús Gallardo Pérez

    2008-03-01

    Full Text Available Se identificaron los conocimientos y conductas de los pacientes con diabetes mellitus sobre el pie diabético. Se realizó un estudio cualitativo en 2 consultorios del Policlínico "Hermanos Ruíz Aboy", del municipio San Miguel del Padrón. Se ejecutaron 4 grupos focales, con un total de 28 participantes de ambos sexos, entre 50 y 80 años de edad. La mayoría de los pacientes mostró falta de conocimientos sobre la definición de pie diabético y sus factores de riesgo. Los pacientes realizan un autocuidado insuficiente de sus pies y asumen conductas de riesgo por la falta de educación. Consideramos importante reforzar el componente educativo en la atención integral de los pacientes con diabetes mellitus para elevar su nivel de conocimientos, crear hábitos saludables y evitar la aparición del pie diabético. La técnica del grupo focal constituyó un instrumento rápido y efectivo para la obtención de información.The knowledge and behavior of the patients with diabetes mellitus in connection with the diabetic foot were identified. A qualitative study was conducted in 2 family physician's offices of "Hermanos Ruíz Aboy" Polyclinic of San Miguel del Padrón municipality. 4 focal groups were selected with a total of 28 participants aged 50-80 of both sexes. Most of the patients lacked knowledge to define the diabetic foot and its risk factors. The patients' self-care of their feet is insufficient and they assume risk conducts due to their deficient education. It is important to reinforce the educative component in the comprehensive attention of the patients with diabetes mellitus to raise their knowledge level, to create healthy habits and to prevent the appearance of diabetic foot. The focal group technique is a rapid and effective tool to obtain information.

  18. Personal authentication through dorsal hand vein patterns

    Science.gov (United States)

    Hsu, Chih-Bin; Hao, Shu-Sheng; Lee, Jen-Chun

    2011-08-01

    Biometric identification is an emerging technology that can solve security problems in our networked society. A reliable and robust personal verification approach using dorsal hand vein patterns is proposed in this paper. The characteristic of the approach needs less computational and memory requirements and has a higher recognition accuracy. In our work, the near-infrared charge-coupled device (CCD) camera is adopted as an input device for capturing dorsal hand vein images, it has the advantages of the low-cost and noncontact imaging. In the proposed approach, two finger-peaks are automatically selected as the datum points to define the region of interest (ROI) in the dorsal hand vein images. The modified two-directional two-dimensional principal component analysis, which performs an alternate two-dimensional PCA (2DPCA) in the column direction of images in the 2DPCA subspace, is proposed to exploit the correlation of vein features inside the ROI between images. The major advantage of the proposed method is that it requires fewer coefficients for efficient dorsal hand vein image representation and recognition. The experimental results on our large dorsal hand vein database show that the presented schema achieves promising performance (false reject rate: 0.97% and false acceptance rate: 0.05%) and is feasible for dorsal hand vein recognition.

  19. 49 CFR 40.361 - What is the purpose of a public interest exclusion (PIE)?

    Science.gov (United States)

    2010-10-01

    ... transportation employers and employees from serious noncompliance with DOT drug and alcohol testing rules, the Department's policy is to ensure that employers conduct business only with responsible service agents. (b... alcohol testing regulations, has shown that it is not currently acting in a responsible manner. (c) A PIE...

  20. Giant Paperclip Necklaces, Soup-Can Rings and Cherry-Pie Hats

    Science.gov (United States)

    Winters, Laurel A.

    2011-01-01

    In this article, the author describes an art project inspired by the wearable sculpture art created by artist Marjorie Schick. Students used wallpaper paste and newspapers to create papier-mache for a mountain hat, a cherry-pie mask/hat, a "dress" shoe and a Cubistic mask. Cardboard was used in many of these things, in addition to being used as…

  1. Moult, pied plumage and relationships within the genus of the Black ...

    African Journals Online (AJOL)

    The pied plumage of the adult Black Sparrowhawk is rather exceptional in the genus Accipiter and it could be explained by functionality or by phylogenetic relationships. The moult pattern of museum specimens is presented, supplementing information from captive birds. The post-juvenile moulting sequence is similar to that ...

  2. Lifting the Curse of the Roman: Quintus Horatius Flaccus Meets the Pied Piper of Hamelin.

    Science.gov (United States)

    Blackburn, William

    There are many similarities between Robert Browning's "The Pied Piper of Hamelin" and Lewis Carroll's "Alice in Wonderland" that are seldom noted by literary critics. Both works were begun for the amusement of specific children, both employ a strange subterranean journey as a central device, and both are works of nonsense…

  3. Fractal Pied de Poule (houndstooth) Collection SS'15 : Parka and Jacket

    NARCIS (Netherlands)

    2015-01-01

    Fractal Pied de Poule (houndstooth) Spring/Summer '15 is a collection consisting of a body, a jacket and a parka. The last two will be shown here. Algorithms, new materials, digital prototyping, drapability, tessellations and fractals are recurring themes in our projects. The body, the jacket and

  4. Proceedings of 2012 JAEA/KAERI joint seminar on advanced irradiation and PIE technologies

    International Nuclear Information System (INIS)

    Ishihara, Masahiro; Ishitsuka, Etsuo; Suzuki, Masahide

    2012-12-01

    Under the 'Arrangement for Corporation in the field of peaceful uses of Nuclear Energy between the Japan Atomic Energy Agency (JAEA) and the Korean Atomic Energy Research Institute (KAERI)', the 2012 JAEA/KAERI Joint Seminar on Advanced Irradiation and PIE (post-irradiation examination) Technologies has been held at Mito, Japan from March 28 to 30, 2012. This triennial seminar is the seventh in series of bilateral exchange of irradiation and PIE technologies and research reactor management. Since the first joint seminar on the PIE Technology between JAERI (Japan Atomic Energy Research Institute, former agency of JAEA) and KAERI was held at JAERI Oarai Research Institute, Japan in 1992, the international cooperation program between JAEA and KAERI has been actively carried out in the field of neutron irradiation. At the fifth seminar in 2005 and sixth in 2008, the irradiation technology and the research reactor management fields were included, respectively, to the joint seminar, and it covers whole areas of irradiation using research reactors. In this seminar total 37 presentations were made in three technical sessions, which are 'research reactor management', 'advanced irradiation technology' and 'post-irradiation examination technology', and active information exchange was done among participants. Papers or manuscripts presented in the 2012 JAEA/KAERI Joint Seminar on Advanced Irradiation and PIE Technologies are contained in the proceedings. (author)

  5. Oxidative stress in pied flycatcher (Ficedula hypoleuca) nestlings from metal contaminated environments in northern Sweden

    International Nuclear Information System (INIS)

    Berglund, A.M.M.; Sturve, J.; Foerlin, L.; Nyholm, N.E.I.

    2007-01-01

    Metals have been shown to induce oxidative stress in animals. One of the most metal polluted terrestrial environments in Sweden is the surroundings of a sulfide ore smelter plant located in the northern part of the country. Pied flycatcher nestlings (Ficedula hypoleuca) that grew up close to the industry had accumulated amounts of arsenic, cadmium, mercury, lead, iron and zinc in their liver tissue. The aim of this study was to investigate if pied flycatcher nestlings in the pollution gradient of the industry were affected by oxidative stress using antioxidant molecules and enzyme activities. The antioxidant assays were also evaluated in search for useful biomarkers in pied flycatchers. This study indicated that nestlings in metal contaminated areas showed signs of oxidative stress evidenced by up regulated hepatic antioxidant defense given as increased glutathione reductase (GR) and catalase (CAT) activities and slightly but not significantly elevated lipid peroxidation and glutathione-S-transferase (GST) activities. Stepwise linear regression indicated that lipid peroxidation and CAT activities were influenced mostly by iron, but iron and lead influenced the CAT activity to a higher degree. Positive relationships were found between GST and lead as well as GR activities and cadmium. We conclude that GR, CAT, GST activities and lipid peroxidation levels may function as useful biomarkers for oxidative stress in free-living pied flycatcher nestlings exposed to metal contaminated environments

  6. Las notas al pie en la traducción de Fifty Shades (Footnotes in the Translation of Fifty Shades

    Directory of Open Access Journals (Sweden)

    Xinia Valverde Jara

    2017-11-01

    Full Text Available Se analiza el recurso de las notas a pie de página insertas en la traducción independiente de literatura comercial en versión digital, de la trilogía Fifty Shades of Grey, Fifty Shades Darker y Fifty Shades Freed, de E. L. James. Se examina el grado de influencia de esos elementos extratextuales, y se concluye que todos ellos, organizados en un complejo proceso de traducción, en especial los del contexto de llegada, condicionan la estrategia traductológica. Abstract This study examines the use of footnotes as a translation strategy in the independent translation of commercial literature in digital format, based on the trilogy written by E. L. James, Fifty Shades of Grey, Fifty Shades Darker and Fifty Shades Freed. The analysis measures the influence of these extratextual elements within the complex translation process, specifically those of the target language context, and it is concluded that they condition the translation strategies used.

  7. International Workshop on Characterization and PIE Needs for Fundamental Understanding of Fuels Performance and Safety

    Energy Technology Data Exchange (ETDEWEB)

    Not Listed

    2011-12-01

    The International Workshop on Characterization and PIE Needs to Support Science-Based Development of Innovative Fuels was held June 16-17, 2011, in Paris, France. The Organization for Economic Co-operation and Development (OECD), Nuclear Energy Agency (NEA) Working Party on the Fuel Cycle (WPFC) sponsored the workshop to identify gaps in global capabilities that need to be filled to meet projected needs in the 21st century. First and foremost, the workshop brought nine countries and associated international organizations, together in support of common needs for nuclear fuels and materials testing, characterization, PIE, and modeling capabilities. Finland, France, Germany, Republic of Korea, Russian Federation, Sweden, Switzerland, United Kingdom, United States of America, IAEA, and ITU (on behalf of European Union Joint Research Centers) discussed issues and opportunities for future technical advancements and collaborations. Second, the presentations provided a base level of understanding of current international capabilities. Three main categories were covered: (1) status of facilities and near term plans, (2) PIE needs from fuels engineering and material science perspectives, and (3) novel PIE techniques being developed to meet the needs. The International presentations provided valuable data consistent with the outcome of the National Workshop held in March 2011. Finally, the panel discussion on 21st century PIE capabilities, created a unified approach for future collaborations. In conclusion, (1) existing capabilities are not sufficient to meet the needs of a science-based approach, (2) safety issues and fuels behavior during abnormal conditions will receive more focus post-Fukushima; therefore we need to adopt our techniques to those issues, and (3) International collaboration is needed in the areas of codes and standards development for the new techniques.

  8. prepare_taxa_charts.py: A Python program to automate generation of publication ready taxonomic pie chart images from QIIME.

    Science.gov (United States)

    Lakhujani, Vijay; Badapanda, Chandan

    2017-06-01

    QIIME (Quantitative Insights Into Microbial Ecology) is one of the most popular open-source bioinformatics suite for performing metagenome, 16S rRNA amplicon and Internal Transcribed Spacer (ITS) data analysis. Although, it is very comprehensive and powerful tool, it lacks a method to provide publication ready taxonomic pie charts. The script plot_taxa_summary . py bundled with QIIME generate a html file and a folder containing taxonomic pie chart and legend as separate images. The images have randomly generated alphanumeric names. Therefore, it is difficult to associate the pie chart with the legend and the corresponding sample identifier. Even if the option to have the legend within the html file is selected while executing plot_taxa_summary . py , it is very tedious to crop a complete image (having both the pie chart and the legend) due to unequal image sizes. It requires a lot of time to manually prepare the pie charts for multiple samples for publication purpose. Moreover, there are chances of error while identifying the pie chart and legend pair due to random alphanumeric names of the images. To bypass all these bottlenecks and make this process efficient, we have developed a python based program, prepare_taxa_charts . py , to automate the renaming, cropping and merging of taxonomic pie chart and corresponding legend image into a single, good quality publication ready image. This program not only augments the functionality of plot_taxa_summary . py but is also very fast in terms of CPU time and user friendly.

  9. Templos con pies de barro. Iglesias y parroquias en la arquitectura rural del Maule

    Directory of Open Access Journals (Sweden)

    Claudia Torres Gilles

    2012-07-01

    Estos conjuntos religiosos permanecen, a pesar de los cambios sociales y los numerosos sismos, gracias a la sabiduría oculta de los sistemas constructivos empleados. En algunos pueblos la comunidad religiosa disminuye y la permanencia de los templos como lugar sacro no es una constante, peligrando así la preservación de este patrimonio rural.

  10. A Comparative Study of Dorsal Buccal Mucosa Graft Substitution Urethroplasty by Dorsal Urethrotomy Approach versus Ventral Sagittal Urethrotomy Approach

    OpenAIRE

    Pahwa, Mrinal; Gupta, Sanjeev; Pahwa, Mayank; Jain, Brig D. K.; Gupta, Manu

    2013-01-01

    Objectives. To compare the outcome of dorsal buccal mucosal graft (BMG) substitution urethroplasty by dorsal urethrotomy approach with ventral urethrotomy approach in management of stricture urethra. Methods and Materials. A total of 40 patients who underwent dorsal BMG substitution urethroplasty were randomized into two groups. 20 patients underwent dorsal onlay BMG urethroplasty as described by Barbagli, and the other 20 patients underwent dorsal BMG urethroplasty by ventral urethrotomy as ...

  11. The impact of conflict issues on fixed-pie perceptions, problem solving, and integrative outcomes in negotiation

    NARCIS (Netherlands)

    Harinck, F.; de Dreu, C.K.W.; van Vianen, A.E.M.

    2000-01-01

    It is argued that a negotiators fixed-pie perception, cooperative motivation, problem-solving behavior, and integrative outcomes are influenced by the content of the negotiationthe conflict issue. Negotiation involves conflicting interests, conflicting ideas about intellective problems, or

  12. Bases fisiológicas del entrenamiento físico en ciclismo

    Directory of Open Access Journals (Sweden)

    M. Rieu

    1993-07-01

    Full Text Available En los deportes en los cuales el desempeño se basa en el desplazamiento horizontal del centro de gravedad del cuerpo, como en el caso de la marcha, la carrera a pie, el ciclismo..., el  objetivo del entrenamiento físico es aumentar la velocidad máxima con la cual se puede efectuar cierto desplazamiento.

  13. Biomecánica del pié diabético: estudio experimental de pacientes con Diabetes Mellitus Tipo I con y sin neuropatía periférica

    OpenAIRE

    Pérez Verdún, Miguel Ángel

    2014-01-01

    La prevalencia de pacientes con diabetes mellitus tipo I en España supone del 10 al 15% del total de los pacientes con diabetes. Algunos estudios apoyan la correlación entre alteraciones biomecánicas del pie y el desarrollo neuropático en diabetes. Objetivo Principal: Relacionar las alteraciones biomecánicas del pie con la presencia de neuropatía periférica de miembros inferiores en pacientes con diabetes mellitus tipo 1. Objetivos secundarios: Conocer los patrones de presión plantar, sup...

  14. Neuroradiological evaluation of dorsal cyst malformations

    International Nuclear Information System (INIS)

    Utsunomiya, Hidetsuna; Hayashi, Takashi; Hashimoto, Takeo; Matsuishi, Toyojiro; Okudera, Toshio.

    1988-01-01

    We discussed six cases with dorsal cyst malformations listing their neuroradiological observations and proposed to differentiate between the holosphere and hemisphere as defined by Yokota (1984). The cases were divided into holospheric and hemispheric groups depending on the continuity of their frontal lobe midlines. Cases 1, 2 and 3 were placed in the holospheric group because of their unseparated frontal lobe sbeneath the partially formed anterior interhemispheric fissures. Cases 4, 5 and 6 were grouped in the hemisphere due to the completion of the interhemispheric fissures. There has been a tendency in recent years for most cases of cerebral malformations having an endogenous dorsal cyst with monoventricular configuration to be diagnosed as holoprosencephaly. However, we believe that only patients who have a dorsal cyst in the holospheric brain should be included, and the others in the hemispheric brain, which is capable of completing hemispheric cleavage, should not. Therefore, we emphasize the importance of correctly identifying the holospheric state in the dorsal cyst malformations for diagnosing holoprosencephaly. (author)

  15. A case of dorsal oblique fingertip amputation.

    Science.gov (United States)

    Takeda, Shinsuke; Tatebe, Masahiro; Morita, Akimasa; Yoneda, Hidemasa; Iwatsuki, Katsuyuki; Hirata, Hitoshi

    2017-01-01

    This study reports successful finger replantation in a patient with a dorsal oblique fingertip amputation. When repairing this unique type of injury, an evaluation of the remaining vessels is more useful for successful replantation than the anatomical zone classification. We propose that Kasai's classification is appropriate for guiding treatment.

  16. A case of dorsal oblique fingertip amputation

    OpenAIRE

    Takeda, Shinsuke; Tatebe, Masahiro; Morita, Akimasa; Yoneda, Hidemasa; Iwatsuki, Katsuyuki; Hirata, Hitoshi

    2017-01-01

    Abstract This study reports successful finger replantation in a patient with a dorsal oblique fingertip amputation. When repairing this unique type of injury, an evaluation of the remaining vessels is more useful for successful replantation than the anatomical zone classification. We propose that Kasai?s classification is appropriate for guiding treatment.

  17. [Characterization and nutritional value of a food artisan: the meat pie of Murcia].

    Science.gov (United States)

    Ruiz-Cano, Domingo; Pérez-Llamas, Francisca; López-Jiménez, José Ángel; González-Silvera, Daniel; Frutos, Maria José; Zamora, Salvador

    2013-01-01

    The main aims of this study are to describe the characteristics of the meat pie, a typical product of the regional gastronomy of Murcia and to determine its nutritional and energy values, fatty acid profile and fat quality. There were studied 24 samples of Murcia's meat pie from the six best-selling retail establishments in this Region (four units per establishment).The moisture, protein, fat, carbohydrates, fibre and minerals, contents and the energy value, fatty acid profile and fat quality were analyzed using the Official Analysis Methods of Foods. All analyses were performed by triplicate. The average weight of this product was 192.3 ± 11.8 g, with three differentiated parts (base, filling and pastry lid). All ingredients were natural raw materials: wheat flour, lard, ground beef, sliced boiled egg and chorizo, water and spices (salt, pepper, garlic, paprika and nutmeg). Most of its organoleptic attributes are due to the type and amount of fat or lard. The combination of the other ingredients and the particular formulation of the spices are also responsible of other attributes. Due to its protein content (11.0%), this meat pie can replace other meat dishes, and be incorporated into a balanced diet. However, it is necessary to take into account its fat and energy contents (17.3 g and 317 kcal/100 g, respectively). Unlike many common pastry products, it contains no trans fatty acids. The results of the research show that the studied product remains, at present, an artisan food, and offer reliable information that it is representative of the energy and nutritional values of the Murcia's meat pie, a typical product of the gastronomy of the Region of Murcia. Copyright © AULA MEDICA EDICIONES 2013. Published by AULA MEDICA. All rights reserved.

  18. A meta-analysis on PewDiePie, his swearing and its development

    OpenAIRE

    Mononen, O. (Ossi)

    2018-01-01

    Abstract This thesis discusses the swearing present in the videos of the YouTube content creator PewDiePie through meta-analysis of a research article on the subject. The thesis will approach the primary article from the points of view of the fields of language play, language policy, ecological language learning and linguistic superdiversities. The primary article is analysed from the point of view of each field in order t...

  19. Trade-offs between sexual advertisement and immune function in the pied flycatcher (Ficedula hypoleuca).

    OpenAIRE

    Kilpimaa, Janne; Alatalo, Rauno V.; Siitari, Heli

    2004-01-01

    Good genes models of sexual selection assume that sexual advertisement is costly and thus the level of advertisement honestly reveals heritable viability. Recently it has been suggested that an important cost of sexual advertisement might be impairment of the functioning of the immune system. In this field experiment we investigated the possible trade-offs between immune function and sexual advertisement by manipulating both mating effort and activity of immune defence in male pied flycatcher...

  20. Current status of PIE activities in O-arai Engineering Center of JNC on FBR MOX fuel

    International Nuclear Information System (INIS)

    Koyama, Shin-ichi; Osaka, Masahiko; Namekawa, Takashi; Itoh, Masahiko

    2003-01-01

    Japan Nuclear Cycle Development Institute (JNC) is now totally promoting the development of commercialized fast reactors to realize stable supply of energy in future. One of the important items is to develop high-performance fuel. For this purpose, it is essential to carry out post-irradiation examinations (PIE) for evaluation of irradiated fuel performance and also to establish the PIE technology. This paper describes the current status of PIE results including its technology in O-arai Engineering Center of JNC. The facilities have been operating safely and successfully since the 1960's. Obtained PIE data were reflected to the design and operation of the experimental fast reactor JOYO, the prototype fast reactor MONJU and future fast reactors. The core modification from the breeding core (MK-I) to the irradiation core (MK-II) of JOYO was performed in 1982. Irradiation tests of fuels and materials in MK-II core started in 1982. At PIE facilities in OEC, 65 of driver fuels, fuel irradiation test rigs, material irradiation test rigs and several other components were examined related to JOYO MK-II core operation, and thus a lot of aspects were accumulated for irradiated fuel behaviors. As topical activities of these PIE techniques, burnup measurement and analytical technique for Minor Actinides (MA), such as neptunium and americium were described here. (author)

  1. PIE on Safety-Tested AGR-1 Compact 5-1-1

    Energy Technology Data Exchange (ETDEWEB)

    Hunn, John D. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Morris, Robert Noel [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Baldwin, Charles A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Montgomery, Fred C. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Gerczak, Tyler J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2015-08-01

    Post-irradiation examination (PIE) is being performed in support of tristructural isotropic (TRISO) coated particle fuel development and qualification for High-Temperature Gas-cooled Reactors (HTGRs). AGR-1 was the first in a series of TRISO fuel irradiation experiments initiated in 2006 under the Advanced Gas Reactor (AGR) Fuel Development and Qualification Program; this work continues to be funded by the Department of Energy's Office of Nuclear Energy as part of the Advanced Reactor Technologies (ART) initiative. AGR-1 fuel compacts were fabricated at Oak Ridge National Laboratory (ORNL) in 2006 and irradiated for three years in the Idaho National Laboratory (INL) Advanced Test Reactor (ATR) to demonstrate and evaluate fuel performance under HTGR irradiation conditions. PIE is being performed at INL and ORNL to study how the fuel behaved during irradiation, and to examine fuel performance during exposure to elevated temperatures at or above temperatures that could occur during a depressurized conduction cooldown event. This report summarizes safety testing of irradiated AGR-1 Compact 5-1-1 in the ORNL Core Conduction Cooldown Test Facility (CCCTF) and post-safety testing PIE.

  2. PIE the search: searching PubMed literature for protein interaction information.

    Science.gov (United States)

    Kim, Sun; Kwon, Dongseop; Shin, Soo-Yong; Wilbur, W John

    2012-02-15

    Finding protein-protein interaction (PPI) information from literature is challenging but an important issue. However, keyword search in PubMed(®) is often time consuming because it requires a series of actions that refine keywords and browse search results until it reaches a goal. Due to the rapid growth of biomedical literature, it has become more difficult for biologists and curators to locate PPI information quickly. Therefore, a tool for prioritizing PPI informative articles can be a useful assistant for finding this PPI-relevant information. PIE (Protein Interaction information Extraction) the search is a web service implementing a competition-winning approach utilizing word and syntactic analyses by machine learning techniques. For easy user access, PIE the search provides a PubMed-like search environment, but the output is the list of articles prioritized by PPI confidence scores. By obtaining PPI-related articles at high rank, researchers can more easily find the up-to-date PPI information, which cannot be found in manually curated PPI databases. http://www.ncbi.nlm.nih.gov/IRET/PIE/.

  3. PIE and separate effect test of high burnup UO2 fuel

    International Nuclear Information System (INIS)

    Yang, Yong Sik; Kim, S.K.; Kim, D.H.

    2005-01-01

    To investigate the performance of a high burnup UO 2 fuel, the highest burnup fuel assembly in KOREA was transported to the PIE facility in KAERI. It was a 17·17 fuel assembly irradiated at the Ulchin Unit 2 PWR. The peak fuel rod average burnup was about 57MWd/kgU and locally 65MWd/kgU. The general PIE was performed to investigate the fuel rod irradiation performance. Fission gas release, burnup, oxide thickness, hydrogen pickup, CRUD, and density change were measured by destructive of non-destructive test. Microstructure change, bubble and pore size distributions were observed by optical microscopy, SEM and EPMA. All generated and available PIE results were used to verify high burnup fuel performance code INFRA. Several rods were cut for additional separate effect test. For the high burnup fission gas release behaviour analysis, annealing apparatus were developed and installed in hot cell and preliminary test was performed. In addition to current apparatus new induction furnace will be installed in hot cell to investigate the high temperature and transient fission gas release behaviour. Ring tensile test was performed to analyze the material property degradation which caused by the oxidation and hydride, and additional mechanical tests will be performed. (Author)

  4. Microbiological evaluation of sweet pies marketed fairs in special city Goiânia-GO

    Directory of Open Access Journals (Sweden)

    Edmar Soares Nicolau

    2014-02-01

    Full Text Available The sweet pies are widely consumed in special fairs in Goiânia-GO city. In general they are marketed in inadequate way, without refrigeration and most of times without any protection against various types of contaminants, including microbial contamination that can cause food toxi-infections to consumers. This study aimed to evaluate the microbiological quality of pies sold in 105 stalls in 23 special fair city of Goiânia, and also the impact of training on the Good Manufacturing Practices (GMP in the quality of these products. The micro-organisms investigated were those required the by standard microbiological: Salmonella, fecal coliforms, Bacillus cereus and Staphylococcus coagulase positive. We also observed the temperature exposure of these foods on newsstands. We analyzed 259 samples in total, with 209 in the first stage, before the training of the fairground, and 50 in the second, after qualifying for the fair dealers in GMP. Pies sweets collected before training of fair dealers were considered unfit for consumption because it contains health indicators above the recommended limit (65.6% with fecal coliforms, 20.6% Staphylococcus coagulase positive and 16.8% with Bacillus cereus. In samples collected after training there was an improvement in the indices (28,0% contained coliforms, 14,0% Staphylococcus coagulase positive and 28,0% of Bacillus cereus, all above the limit set. None samples had Salmonella in both steps. It can be concluded that with the training of fair dealers there was an improvement in the microbiological quality of these products. These results reinforce the need for training of the fairground and the impact it can have on the quality of the products. The storage temperatures pies ranged from –5.3ºC to 28.7ºC in first step and –3.6ºC to 24.0ºC in the second. The presence of the refrigerated was not sufficient to maintain the optimal temperature (to 10 ° C for storage of pies.

  5. Active basement uplift as seen with cosmogenic lenses: the Sierra Pie de Palo case (Western Argentina)

    Science.gov (United States)

    Siame, L. L.; Sébrier, M.; Costa, C. H.; Ahumada, E. A.; Bellier, O.

    2013-12-01

    The Andean foreland of western Argentina (28°S-33°S) corresponds to retroarc deformations associated with the ongoing flat subduction of the Nazca plate beneath the South American lithosphere, and associated with high levels of seismic activity and crustal active faulting. To improve earthquake source identification and characterization in the San Juan region, data from seismology, structural geology and quantitative geomorphology can be integrated and combined to provide a seismotectonic model. In this model, the Andean back-arc of western Argentina has to be regarded as an obliquely converging foreland where Plio-Quaternary deformations are partitioned between strike-slip and thrust motions that are localized on the E-verging, thin-skinned Argentine Precordillera, and the W-verging thick-skinned Sierras Pampeanas, respectively. In this domain, the Sierra Pie de Palo is a key structure playing a major role in the partitioning of the Plio-Quaternary deformations. Located in the westernmost Sierras Pampeanas, the Sierra Pie de Palo forms a NNE striking, 80 km-long and 35-40 km-wide, ellipsoid range that reaches elevation as high as 3162 m. This mountain range is an actively growing basement fold associated with a high level of seismic activity (e.g., the November 23, 1977, Caucete, Mw 7.4 earthquake). To evaluate the degree of tectonic activity around the Sierra Pie de Palo, we combined a detailed morphometric analysis of the topography together with in situ-produced cosmogenic 10Be concentrations measured in (1) bedrock outcrops corresponding to the exhumed erosional regional surface, (2) surface boulders abandoned on alluvial fans deformed by active faults, and (3) in fluvial sediments sampled at the outlets of selected watersheds that drains out from the Sierra Pie de Palo. All together, our results allows: (1) assessing quantitative constraints on the rate of tectonic and denudation processes that are responsible for the active growth and erosion of the Sierra

  6. Arquitectura vernácula de la zona baja de la cuenca hidrográfica del guayas: viviendas urbanas y rurales

    Directory of Open Access Journals (Sweden)

    Claudia María Peralta González

    2014-12-01

    Algunas edificaciones aún siguen en pie, tanto en el área urbana como rural, pese a la indiferencia que ha habido hacia este tipo de arquitectura, cuyo aporte sigue sin reconocerse totalmente cuando se habla del patrimonio construido del Ecuador.

  7. The dorsal shell wall structure of Mesozoic ammonoids

    Directory of Open Access Journals (Sweden)

    Gregor Radtke

    2017-03-01

    Full Text Available The study of pristine preserved shells of Mesozoic Ammonoidea shows different types of construction and formation of the dorsal shell wall. We observe three major types: (i The vast majority of Ammonoidea, usually planispirally coiled, has a prismatic reduced dorsal shell wall which consists of an outer organic component (e.g., wrinkle layer, which is the first layer to be formed, and the subsequently formed dorsal inner prismatic layer. The dorsal mantle tissue suppresses the formation of the outer prismatic layer and nacreous layer. With the exception of the outer organic component, secretion of a shell wall is omitted at the aperture. A prismatic reduced dorsal shell wall is always secreted immediately after the hatching during early teleoconch formation. Due to its broad distribution in (planispiral Ammonoidea, the prismatic reduced dorsal shell wall is probably the general state. (ii Some planispirally coiled Ammonoidea have a nacreous reduced dorsal shell wall which consists of three mineralized layers: two prismatic layers (primary and secondary dorsal inner prismatic layer and an enclosed nacreous layer (secondary dorsal nacreous layer. The dorsal shell wall is omitted at the aperture and was secreted in the rear living chamber. Its layers are a continuation of an umbilical shell doubling (reinforcement by additional shell layers that extends towards the ventral crest of the preceding whorl. The nacreous reduced dorsal shell wall is formed in the process of ontogeny following a prismatic reduced dorsal shell wall. (iii Heteromorph and some planispirally coiled taxa secrete a complete dorsal shell wall which forms a continuation of the ventral and lateral shell layers. It is formed during ontogeny following a prismatic reduced dorsal shell wall or a priori. The construction is identical with the ventral and lateral shell wall, including a dorsal nacreous layer. The wide distribution of the ability to form dorsal nacre indicates that it is

  8. Avancée dans la prévention des « chutes de plain-pied » au travail Progress in the prevention of occupational “falls on the same level”. Proposed operational definition of a new category: “Motion perturbation accidents (MPAs” Avances en la prevención de « caídas al mismo nivel » en el trabajo. Propuesta de la definición operacional de una nueva categoría : « los Accidentes con Perturbación del Movimiento (APM »

    Directory of Open Access Journals (Sweden)

    Sylvie Leclercq

    2010-11-01

    Full Text Available La chute de plain-pied reste un accident du travail fréquent et grave. La terminologie qualifiant ces accidents est variée, relativement imprécise et n’intègre pas la diversité des accidents rencontrés sous les différentes appellations. L’intérêt de considérer une catégorie d’accidents du travail avec perturbation du mouvement (APM est tout d’abord mis en évidence à partir de divers extraits de récits d’accidents. Un modèle est ensuite proposé pour les APM montrant que, dans ces cas particuliers d’accident la blessure est souvent la conséquence de l’association fortuite entre l’énergie du mouvement perturbé de la victime et un élément matériel rendu blessant de par ses propriétés et appelé a posteriori un « danger circonstanciel ». Enfin, le raisonnement qui sous-tend la classification de ces accidents est explicité. Il apparaît notamment que la prévention ciblant les causes immédiates de la blessure est difficile voire impossible dans les cas d’APM en raison principalement des exigences inhérentes au travail et de contraintes que ferait peser sur l’entreprise l’application de cette prévention. La prévention à la source du risque tend alors à devenir la seule possible. Ainsi, de banal, l’APM devient un révélateur de dysfonctionnements au sein du système de production.Falls on the same level remain frequent and serious occupational accidents. The terminology used to describe these accidents is varied and somewhat imprecise. Moreover it does not integrate the variety of accidents with different names. The advantage of considering an occupational accident category with motion perturbation (MPA is demonstrated, based on extracts from various occupational accident accounts. A model is then proposed for MPAs that shows that in these specific cases of accidents, the injury often results from a fortuitous association between the victim’ perturbed motion energy and a physical element that

  9. Poesía del padre Briceño Jáuregui

    Directory of Open Access Journals (Sweden)

    Antonio J. Pérez H.

    1963-03-01

    Full Text Available En la Revista Javeriana (abril de 1962 apareció un haz de sonetos cincelados al pie mismo de los mármoles vetustos de Atica. Un poeta autóctono, virtuoso del clasicismo heleno, casi anónimo en meido de esta desazón literaria en que vivimos.

  10. Spatial distribution of breeding Pied Flycatchers Ficedula hypoleuca in respect to their natal sites

    Directory of Open Access Journals (Sweden)

    Sokolov, L.

    2004-06-01

    Full Text Available Study of philopatry and dispersal of pied flycatchers Ficedula hypoleuca was launched on the Courish Spit (SE Baltic in 1981. Since then, ca. 9,000 nestlings were ringed at different sites in the Russian part of the Courish Spit. A total of 557 individuals ringed as pulli were recaptured in subsequent seasons in the study area. Both males and females are more often recaptured in the plots where they were ringed than in other plots. These results were interpreted in the framework of the hypothesis forwarded by Löhrl (1959 and supported by Berndt & Winkel (1979. These authors suggested that cavity nesters (pied flycatchers and collared flycatchers F. albicollis imprint their future local breeding area during the period of postfledging exploration. Birds that survive until the next spring, return to these imprinted areas to breed. A similar study done by Sokolov et al. (1984 on the Courish Spit in an open nesting species, the chaffinch Fringilla coelebs, confirmed this finding. We assumed that juvenile pied flycatchers disperse for varying distances during their postfledging movements and imprint a local area, some 1–5 kilometres in diameter. This area is the goal of their migration next spring. It is suggested that in spring, yearlings are non–randomly distributed in respect to the area they have imprinted as juveniles. Recently, Vysotsky (2000, 2001 re–analysed the same data on philopatry of pied flycatchers on the Courish Spit and forwarded an alternative hypothesis. He suggests that juveniles, both males and females, do not imprint any local area during the postfledging period, but are distributed randomly across the area of several dozens of kilometres in spring. Vysotsky was able to show that distribution of distances of natal dispersal did not differ from the random pattern the study plot which was an 8.5 km long line of nest boxes along the Courish Spit. The aim of this study was to test these two alternative hypotheses. To do so, we

  11. Endogenous neurotrophin-3 promotes neuronal sprouting from dorsal root ganglia.

    Science.gov (United States)

    Wang, Xu-Yang; Gu, Pei-Yuan; Chen, Shi-Wen; Gao, Wen-Wei; Tian, Heng-Li; Lu, Xiang-He; Zheng, Wei-Ming; Zhuge, Qi-Chuan; Hu, Wei-Xing

    2015-11-01

    In the present study, we investigated the role of endogenous neurotrophin-3 in nerve terminal sprouting 2 months after spinal cord dorsal root rhizotomy. The left L1-5 and L7-S2 dorsal root ganglia in adult cats were exposed and removed, preserving the L6 dorsal root ganglia. Neurotrophin-3 was mainly expressed in large neurons in the dorsal root ganglia and in some neurons in spinal lamina II. Two months after rhizotomy, the number of neurotrophin-3-positive neurons in the spared dorsal root ganglia and the density of neurite sprouts emerging from these ganglia were increased. Intraperitoneal injection of an antibody against neurotrophin-3 decreased the density of neurite sprouts. These findings suggest that endogenous neurotrophin-3 is involved in spinal cord plasticity and regeneration, and that it promotes axonal sprouting from the dorsal root ganglia after spinal cord dorsal root rhizotomy.

  12. Detection of rhodopsin dimerization in situ by PIE-FCCS, a time-resolved fluorescence spectroscopy.

    Science.gov (United States)

    Smith, Adam W

    2015-01-01

    Rhodopsin self-associates in the plasma membrane. At low concentrations, the interactions are consistent with a monomer-dimer equilibrium (Comar et al., J Am Chem Soc 136(23):8342-8349, 2014). At high concentrations in native tissue, higher-order clusters have been observed (Fotiadis et al., Nature 421:127-128, 2003). The physiological role of rhodopsin dimerization is still being investigated, but it is clear that a quantitative assessment is essential to determining the function of rhodopsin clusters in vision. To quantify rhodopsin interactions, I will outline the theory and methodology of a specialized time-resolved fluorescence spectroscopy for measuring membrane protein-protein interactions called pulsed-interleaved excitation fluorescence cross-correlation spectroscopy (PIE-FCCS). The strength of this technique is its ability to quantify rhodopsin interactions in situ (i.e., a live cell plasma membrane). There are two reasons for restricting the scope to live cell membranes. First, the compositional heterogeneity of the plasma membrane creates a complex milieu with thousands of lipid, protein, and carbohydrate species. This makes it difficult to infer quaternary interactions from detergent solubilized samples or construct a model phospholipid bilayer that recapitulates all of the interactions present in native membranes. Second, organizational structure and dynamics is a key feature of the plasma membrane, and fixation techniques like formaldehyde cross-linking and vitrification will modulate the interactions. PIE-FCCS is based on two-color fluorescence imaging with time-correlated single-photon counting (TCSPC) (Becker et al., Rev Sci Instrum 70:1835-1841, 1999). By time-tagging every detected photon, the data can be analyzed as a fluorescence intensity distribution, fluorescence lifetime histogram, or fluorescence (cross-)correlation spectra (FCS/FCCS) (Becker, Advanced time-correlated single-photon counting techniques, Springer, Berlin, 2005). These

  13. Calling Where It Counts: Subordinate Pied Babblers Target the Audience of Their Vocal Advertisements.

    Science.gov (United States)

    Humphries, David J; Finch, Fiona M; Bell, Matthew B V; Ridley, Amanda R

    2015-01-01

    For territorial group-living species, opportunities to reproduce on the natal territory can be limited by a number of factors including the availability of resources within a territory, access to unrelated individuals, and monopolies on reproduction by dominant group members. Individuals looking to reproduce are therefore faced with the options of either waiting for a breeding opportunity to arise in the natal territory, or searching for reproductive opportunities in non-natal groups. In the cooperatively breeding Southern pied babbler, Turdoides bicolor, most individuals who achieve reproductive success do so through taking up dominant breeding positions within non-natal groups. For subordinate pied babblers therefore, searching for breeding opportunities in non-natal groups is of primary importance as this represents the major route to reproductive success. However, prospecting (where individuals leave the group to search for reproductive opportunities within other groups) is costly and individuals rapidly lose weight when not part of a group. Here we demonstrate that subordinate pied babblers adopt an alternative strategy for mate attraction by vocal advertisement from within their natal territories. We show that subordinates focus their calling efforts on the edges of their territory, and specifically near boundaries with neighbouring groups that have potential breeding partners (unrelated individuals of the opposite sex). In contrast to prospecting, calling individuals showed no body mass loss associated with this behaviour, suggesting that calling from within the group may provide a 'cheap' advertisement strategy. Additionally, we show that subordinates use information regarding the composition of neighbouring groups to target the greatest number of potential mating partners.

  14. Recent improvements in PIE-techniques at the IFE hot-laboratory

    International Nuclear Information System (INIS)

    Jenssen, Haakon Kristian

    1999-01-01

    The PIE-techniques at the IFE nuclear fuel section are continuously improved through upgrading of equipment and methods, e.g. image handling techniques and components utilised in data acquisition and editing techniques. To improve the quality or spatial resolution of neutron radiographs the normal technique was complemented with another method. The dysprosium foil/X-ray film technique is now supplemented with a track-etch recorder consisting of a cellulose nitrate film. For further examination the cellulose nitrate film can be digitised to allow electronic image treatment. Promising results were obtained with this technique on neutron radiographs, namely higher spatial resolution compared to the normal technique, high contrast and sharp neutron radiography images. The traditional one-axial profilometry of fuel rods were modified so that diameter/bow measurements are possible at several angular orientations during one acquisition sequence. This extension is very useful in several ways, for instance the built-in data symmetry of the method is used to check the correctness of the measurement results. Diameter and bow measurements give in addition detailed and complete information of canning irregularities and fuel rod profiles. PIE data are collected and compiled in an image file. Inspection and examination of the file information is possible through an ideal user-interface, i.e. Adobe photoshop software with navigator possibilities. An example incorporating PIE data acquired from a fuel rod exposed in a loss of coolant experiment is utilised for illustration of the user-interface and some of its possibilities (author) (ml)

  15. Proceedings of 2008 KAERI/JAEA joint seminar on advanced irradiation and PIE technologies

    International Nuclear Information System (INIS)

    Ryu, Woo-Seog; Ishihara, Masahiro

    2008-12-01

    Under the Arrangement for Cooperation in the field of peaceful uses of Nuclear Energy between the Korea Atomic Energy Research Institute (KAERI) and the Japan Atomic Energy Agency (JAEA), the 2008 KAERI-JAEA Joint Seminar on Advanced Irradiation and PIE (post-irradiation examination) Technologies has been held at KAERI in Daejeon, Korea, from November 5 to 7, 2008. This seminar was organized by the PIE and Radwaste Division, Research Reactor Engineering Division, and HANARO Management Division in KAERI. It was also the first time to hold the seminar under the agreement signed September 4, 2008. This triennial seminar is the sixth in series of bilateral exchange of irradiation technologies. Since the first joint seminar on Post Irradiation Examination Technology between JAERI and KAERI held at JAERI Oarai center, Japan in 1992, it has been a good model of international cooperation program between KAERI and JAEA in the field of neutron irradiation uses. At the fifth seminar in 2005, irradiation technology field was included to the joint seminar, moreover in this time it is expanded to the research reactor management field for covering whole areas of irradiation using in research reactors. The seminar was divided into three technical sessions; the sessions addressed the general topics of 'research reactor management', 'advanced irradiation technology' and 'post-irradiation examination technology'. Total 46 presentations were made, and active information exchange was done among participants. This proceeding is containing the papers or manuscripts presented in the 2008 KAERI-JAEA Joint Seminar on Advanced Irradiation and PIE Technologies. The 46 of the presented papers indexed individually. (J.P.N.)

  16. Radiographic Outcomes of Dorsal Distraction Distal Radius Plating for Fractures With Dorsal Marginal Impaction.

    Science.gov (United States)

    Huish, Eric G; Coury, John G; Ibrahim, Mohamed A; Trzeciak, Marc A

    2017-04-01

    The purpose of this study is to compare radiographic outcomes of patients treated with dorsal spanning plates with previously reported normal values of radiographic distal radius anatomy and compare the results with prior publications for both external fixation and internal fixation with volar locked plates. Patients with complex distal radius fractures including dorsal marginal impaction pattern necessitating dorsal distraction plating at the discretion of the senior authors (M.A.T. and M.A.I.) from May 30, 2013, to December 29, 2015, were identified and included in the study. Retrospective chart and radiograph review was performed on 19 patients, 11 male and 8 female, with mean age of 47.83 years (22-82). No patients were excluded from the study. All fractures united prior to plate removal. The average time the plate was in place was 80.5 days (49-129). Follow-up radiographs showed average radial inclination of 20.5° (13.2°-25.5°), radial height of 10.7 mm (7.5-14 mm), ulnar variance of -0.3 mm (-2.1 to 3.1 mm), and volar tilt of 7.9° (-3° to 15°). One patient had intra-articular step-off greater than 2 mm. Dorsal distraction plating of complex distal radius fractures yields good radiographic results with minimal complications. In cases of complex distal radius fractures including dorsal marginal impaction where volar plating is not considered adequate, a dorsal distraction plate should be considered as an alternative to external fixation due to reduced risk for infection and better control of volar tilt.

  17. Energy use in the bread, cake, pastry, and pie baking industries

    Energy Technology Data Exchange (ETDEWEB)

    Cleland, A.C.; Earle, M.D.; Serrallach, G.F.

    1980-05-01

    A survey was carried out to determine energy consumption in the bread, cake, pastry, and pie baking industry. Information was obtained from 11 bread bakeries. Energy use in the bread bakeries over the period 1977/78 was found to average 2.45 MJ/kg of which 0.46 MJ/kg was electricity and the rest oven and boiler fuels. Process flow charts are shown. The purposes for which electricity are used are described. An energy consumption analysis is presented and energy conservation measures are described. (MCW)

  18. Preposition stranding versus pied-piping: Negative Shift of prepositional complements in dialects of Faroese

    Directory of Open Access Journals (Sweden)

    Eva Engels

    2009-01-01

             These asymmetries will be accounted for within Fox and Pesetsky's (2003, 2005 cyclic linearization model, which requires non-string-vacuous movement to proceed through the left edge of Spell-out domains, deriving cross-linguistic variation as to Negative Shift from differences in the availability of these left-edge positions. Thereby, pied-piping is considered a last resort strategy, possible only if the prepositional complement cannot undergo Negative Shift on its own due to the unavailability of the relevant left-edge position.

  19. Dorsal and ventral streams across sensory modalities

    Institute of Scientific and Technical Information of China (English)

    Anna Sedda; Federica Scarpina

    2012-01-01

    In this review,we describe the current models of dorsal and ventral streams in vision,audition and touch.Available theories take their first steps from the model of Milner and Goodale,which was developed to explain how human actions can be efficiently carried out using visual information.Since then,similar concepts have also been applied to other sensory modalities.We propose that advances in the knowledge of brain functioning can be achieved through models explaining action and perception patterns independently from sensory modalities.

  20. MOVIMIENTOS DE LADERA Y PLANEAMIENTO URBANÍSTICO: EL CONFLICTO DEL CERRO DEL OPE, ARCHENA (MURCIA

    Directory of Open Access Journals (Sweden)

    María Dolores Gómez Moreno

    2009-01-01

    Full Text Available Los desprendimientos son un proceso natural que afecta, de forma generalizada en el Valle de Ricote, a las laderas del tipo cantil-talud. Su peligrosidad radica en que los bloques desprendidos del escarpe ruedan con facilidad, talud abajo, cuando son descalzados por efecto de la escorrentía superfi cial o desestabilizados por movimientos sísmicos. El planeamiento urbanístico se convierte en factor inductor del riesgo al clasifi car como urbanizables y urbanos suelos que, por su ubicación en pie de ladera, deberían excluirse de cualquier proceso urbanizador. Este es el caso de Archena en el entorno inmediato del cerro del Ope.

  1. The relationship of family characteristics and bipolar disorder using causal-pie models.

    Science.gov (United States)

    Chen, Y-C; Kao, C-F; Lu, M-K; Yang, Y-K; Liao, S-C; Jang, F-L; Chen, W J; Lu, R-B; Kuo, P-H

    2014-01-01

    Many family characteristics were reported to increase the risk of bipolar disorder (BPD). The development of BPD may be mediated through different pathways, involving diverse risk factor profiles. We evaluated the associations of family characteristics to build influential causal-pie models to estimate their contributions on the risk of developing BPD at the population level. We recruited 329 clinically diagnosed BPD patients and 202 healthy controls to collect information in parental psychopathology, parent-child relationship, and conflict within family. Other than logistic regression models, we applied causal-pie models to identify pathways involved with different family factors for BPD. The risk of BPD was significantly increased with parental depression, neurosis, anxiety, paternal substance use problems, and poor relationship with parents. Having a depressed mother further predicted early onset of BPD. Additionally, a greater risk for BPD was observed with higher numbers of paternal/maternal psychopathologies. Three significant risk profiles were identified for BPD, including paternal substance use problems (73.0%), maternal depression (17.6%), and through poor relationship with parents and conflict within the family (6.3%). Our findings demonstrate that different aspects of family characteristics elicit negative impacts on bipolar illness, which can be utilized to target specific factors to design and employ efficient intervention programs. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

  2. Pie waste - A component of food waste and a renewable substrate for producing ethanol.

    Science.gov (United States)

    Magyar, Margaret; da Costa Sousa, Leonardo; Jayanthi, Singaram; Balan, Venkatesh

    2017-04-01

    Sugar-rich food waste is a sustainable feedstock that can be converted into ethanol without an expensive thermochemical pretreatment that is commonly used in first and second generation processes. In this manuscript we have outlined the pie waste conversion to ethanol through a two-step process, namely, enzyme hydrolysis using commercial enzyme products mixtures and microbial fermentation using yeast. Optimized enzyme cocktail was found to be 45% alpha amylase, 45% gamma amylase, and 10% pectinase at 2.5mg enzyme protein/g glucan produced a hydrolysate with high glucose concentration. All three solid loadings (20%, 30%, and 40%) produced sugar-rich hydrolysates and ethanol with little to no enzyme or yeast inhibition. Enzymatic hydrolysis and fermentation process mass balance was carried out using pie waste on a 1000g dry weight basis that produced 329g ethanol at 20% solids loading. This process clearly demonstrate how food waste could be efficiently converted to ethanol that could be used for making biodiesel by reacting with waste cooking oil. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. Stuffed Turkey and Pumpkin Pie: In, Through and Out of American Contexts

    Directory of Open Access Journals (Sweden)

    Tamara Kohn

    2013-02-01

    Full Text Available This article explores the meanings embedded in the production, consumption, and symbolic positioning of turkey and pumpkin pie, foods closely associated with the American ritual feast of Thanksgiving. An analysis of turkey and pumpkin pie recipes used and adapted by first- and second-generation immigrants in north America, and by north Americans living abroad, throws into relief complex relations between food production, food consumption and the complexities of lived and often multiple sociocultural identifications. Through sharing the experiences, memories and associations evoked by individuals in the production of holiday recipes, I argue that ideas about ‘tradition’ and a desire to celebrate family and community through the ritual of baking, serving and consuming a ‘standard’ Thanksgiving holiday meal allow one to feel part of an imagined global American community. At the same time these details demonstrate celebration of individual and familial distinctiveness that is traced to (sometimes contested memories of childhood and/or ethnic background, as well as to exploration, innovation and experience in the world at large through travel, migration and imagination.

  4. Local survival of pied flycatcher males and females in a pollution gradient of a Cu smelter

    International Nuclear Information System (INIS)

    Eeva, T.; Hakkarainen, H.; Belskii, E.

    2009-01-01

    Survival is one of the most central population measures when the effects of the pollution are studied in natural bird populations. However, only few studies have actually measured rigorous survival estimates on adult birds. In recent years there has been a methodological advance in survival analyses by mark-recapture models. We modelled local survival (including mortality and emigration) with the program MARK in a population of a small insectivorous passerine bird, the pied flycatcher (Ficedula hypoleuca), around a point source of heavy metals. The local survival of females in the polluted area was about 50% lower than in the other areas. Males, however, survived relatively well in the heavily polluted area, but showed somewhat lower survival in the moderately polluted area. Different pollution effects between two sexes might be due to pollution-related differences in reproductive effort in females and males, and/or more intensive uptake of heavy metals by laying females. - Female pied flycatchers (Ficedula hypoleuca) show decreased local survival around a copper smelter.

  5. The PIES2012 Code for Calculating 3D Equilibria with Islands and Stochastic Regions

    Science.gov (United States)

    Monticello, Donald; Reiman, Allan; Raburn, Daniel

    2013-10-01

    We have made major modifications to the PIES 3D equilibrium code to produce a new version, PIES2012. The new version uses an adaptive radial grid for calculating equilibrium currents. A subset of the flux surfaces conform closely to island separatrices, providing an accurate treatment of the effects driving the neoclassical tearing mode. There is now a set of grid surfaces that conform to the flux surfaces in the interiors of the islands, allowing the proper treatment of the current profiles in the islands, which play an important role in tearing phenomena. We have verified that we can introduce appropriate current profiles in the islands to suppress their growth, allowing us to simulate situations where islands are allowed to grow at some rational surfaces but not others. Placement of grid surfaces between islands is guided by the locations of high order fixed points, allowing us to avoid spectral polution and providing a more robust, and smoother convergence of the code. The code now has an option for turning on a vertical magnetic field to fix the position of the magnetic axis, which models the horizontal feedback positioning of a tokamak plasma. The code has a new option for using a Jacobian-Free Newton Krylov scheme for convergence. The code now also contains a model that properly handles stochastic regions with nonzero pressure gradients. Work supported by DOE contract DE-AC02-09CH11466.

  6. PIE on Safety-Tested Loose Particles from Irradiated Compact 4-4-2

    Energy Technology Data Exchange (ETDEWEB)

    Hunn, John D. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Gerczak, Tyler J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Morris, Robert Noel [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Baldwin, Charles A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Montgomery, Fred C. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-04-01

    Post-irradiation examination (PIE) is being performed in support of tristructural isotropic (TRISO) coated particle fuel development and qualification for High Temperature Gas-cooled Reactors (HTGRs). This work is sponsored by the Department of Energy Office of Nuclear Energy (DOE-NE) through the Advanced Reactor Technologies (ART) Office under the Advanced Gas Reactor Fuel Development and Qualification (AGR) Program. The AGR-1 experiment was the first in a series of TRISO fuel irradiation tests initiated in 2006. The AGR-1 TRISO particles and fuel compacts were fabricated at Oak Ridge National Laboratory (ORNL) in 2006 using laboratory-scale equipment and irradiated for 3 years in the Advanced Test Reactor (ATR) at Idaho National Laboratory (INL) to demonstrate and evaluate fuel performance under HTGR irradiation conditions. Post-irradiation examination was performed at INL and ORNL to study how the fuel behaved during irradiation, and to test fuel performance during exposure to elevated temperatures at or above temperatures that could occur during a depressurized conduction cooldown event. This report summarizes safety testing and post-safety testing PIE conducted at ORNL on loose particles extracted from irradiated AGR-1 Compact 4-4-2.

  7. PROJECTIONS OF DORSAL AND MEDIAN RAPHE NUCLEI TO DORSAL AND VENTRAL STRIATUM

    Directory of Open Access Journals (Sweden)

    G. R. Hassanzadeh G. Behzadi

    2007-08-01

    Full Text Available The ascending serotonergic projections are derived mainly from mesencephalic raphe nuclei. Topographical projections from mesencephalic raphe nuclei to the striatum were examined in the rat by the retrograde transport technique of HRP (horseradish peroxidase. In 29 rats stereotaxically injection of HRP enzyme were performed in dorsal and ventral parts of striatum separately. The extent of the injection sites and distribution of retrogradely labeled neuronal cell bodies were drawed on representative sections using a projection microscope. Following ipsilateral injection of HRP into the dorsal striatum, numerous labeled neurons were seen in rostral portion of dorsal raphe (DR nucleus. In the same level the cluster of labeled neurons were hevier through caudal parts of DR. A few neurons were also located in lateral wing of DR. More caudally some labeled neurons were found in lateral, medial line of DR. In median raphe nucleus (MnR the labeled neurons were scattered only in median portion of this nucleus. The ipsilateral injection of HRP into the ventral region of striatum resulted on labeling of numerous neurons in rostral, caudal and lateral portions of DR. Through the caudal extension of DR on 4th ventricle level, a large number of labeled neurons were distributed along the ventrocaudal parts of DR. In MnR, labeled neurons were observed only in median part of this nucleus. These findings suggest the mesencephalic raphe nuclei projections to caudo-putamen are topographically organized. In addition dorsal and median raphe nuclei have a stronger projection to the ventral striatum.

  8. Técnica de Imhäuser en el pie zambo : resultados a medio y largo plazo

    OpenAIRE

    Fernández Gutiérrez, C.; Núñez Batalla, Daniel; Pena Vázquez, J.; Antuña Antuña, S.; González Méndez, J.; López Fernández, P; Paz Jiménez, José

    1996-01-01

    Se revisan un total de 60 pies con equinovaro congénito pertenecientes a 48 pacientes, todos con un seguimiento superior a 5 años. En todos los casos se realizó un tratamiento combinado: ortopédico (manipulaciones y enyesados desde el nacimiento) y quirúrgico (correcciones según el método de Imhäuser modificado). Se valoró morfológica, funcional y radiográficamente cada caso. En la valoración global sólo 1 caso fue considerado malo, 13 regulares (21,6%), 6 por pies planos valgo...

  9. A proposal for laminated pie mechanical construction of a toroidal magnet for the far detector for the MINOS experiment

    International Nuclear Information System (INIS)

    Fields, T.; Guarino, V.; Petereit, E.; Schoessow, P.; Thompson, K.

    1996-01-01

    This proposal describes an alternative to the reference design for the construction of the toroidal magnet for the detector for the MINOS experiment. This design proposes to construct the steel planes from several steel sheets and laminate them into the required thickness of four centimeters. The 8 meter planes are constructed by cutting all of the steel plates to the same size, which is pie a pie shaped segment of either 30 or 22.5 degrees each. All of the plates in the construction are identical, which is conducive to rapid production and lower cost. The advantages of the proposed laminated construction over the reference design are listed in this paper

  10. Versatility of the ventral approach in bulbar urethroplasty using dorsal, ventral or dorsal plus ventral oral grafts

    OpenAIRE

    Palminteri, Enzo; Berdondini, Elisa; Fusco, Ferdinando; Nunzio, Cosimo De; Giannitsas, Kostas; Shokeir, Ahmed A.

    2012-01-01

    Objectives To investigate the versatility of the ventral urethrotomy approach in bulbar reconstruction with buccal mucosa (BM) grafts placed on the dorsal, ventral or dorsal plus ventral urethral surface. Patients and methods Between 1999 and 2008, 216 patients with bulbar strictures underwent BM graft urethroplasty using the ventral-sagittal urethrotomy approach. Of these patients, 32 (14.8%; mean stricture 3.2?cm, range 1.5?5) had a dorsal graft urethroplasty (DGU), 121 (56%; mean stricture...

  11. "A New Kind of Rule": The Subversive Narrator in "Alice's Adventures in Wonderland" and "The Pied Piper of Hamelin."

    Science.gov (United States)

    Blackburn, William

    1986-01-01

    Compares "Alice's Adventures in Wonderland" to "The Pied Piper of Hamelin," noting that both: (1) were begun for the amusement of specific children; (2) use a subterranean journey as a device; (3) are critical of social authority; and (4) have problematic endings. (SRT)

  12. Slow improvements of metal exposure, health- and breeding conditions of pied flycatchers (Ficedula hypoleuca) after decreased industrial heavy metal emissions

    International Nuclear Information System (INIS)

    Berglund, A.M.M.; Nyholm, N.E.I.

    2011-01-01

    The environment around metal industries, such as smelters, is often highly contaminated due to continuous deposition of metals. We studied nest box breeding populations of pied flycatchers (Ficedula hypoleuca) in a well-studied pollution gradient from a sulfide ore smelter in Northern Sweden, after reduced aerial metal emissions (by 93-99%) from the smelter. The deposition of arsenic, cadmium, copper and zinc (based on moss samples) reflected the reduced emissions fairly well. However, nestling pied flycatchers had similar concentrations of these elements and mercury in tissues (bone, liver and blood) and feces in the 2000s, as in the 1980s, when the emissions were substantially higher. The exposure to high metal concentrations in the close vicinity of the smelter resulted in inhibited ALAD activities, depressed hemoglobin and hematocrit levels and increased mortality of nestlings. Our results indicate that in the highly contaminated environment around the smelter, nestlings reflected the slowly cycling soil pool, rather than the atmospheric deposition, and the concentration in soils plays an important role for the response of pied flycatchers to reduced atmospheric deposition. - Highlights: → Pied flycatchers were studied in a pollution gradient from a sulfide smelter. → Metal emissions from the smelter have decreased substantially. → Nestling birds still had high metal concentrations in tissues. → Health and survival rates of nestlings were negatively affected. → Recovery of birds is not expected in the near future.

  13. Slow improvements of metal exposure, health- and breeding conditions of pied flycatchers (Ficedula hypoleuca) after decreased industrial heavy metal emissions

    Energy Technology Data Exchange (ETDEWEB)

    Berglund, A.M.M., E-mail: asa.berglund@emg.umu.se; Nyholm, N.E.I.

    2011-09-15

    The environment around metal industries, such as smelters, is often highly contaminated due to continuous deposition of metals. We studied nest box breeding populations of pied flycatchers (Ficedula hypoleuca) in a well-studied pollution gradient from a sulfide ore smelter in Northern Sweden, after reduced aerial metal emissions (by 93-99%) from the smelter. The deposition of arsenic, cadmium, copper and zinc (based on moss samples) reflected the reduced emissions fairly well. However, nestling pied flycatchers had similar concentrations of these elements and mercury in tissues (bone, liver and blood) and feces in the 2000s, as in the 1980s, when the emissions were substantially higher. The exposure to high metal concentrations in the close vicinity of the smelter resulted in inhibited ALAD activities, depressed hemoglobin and hematocrit levels and increased mortality of nestlings. Our results indicate that in the highly contaminated environment around the smelter, nestlings reflected the slowly cycling soil pool, rather than the atmospheric deposition, and the concentration in soils plays an important role for the response of pied flycatchers to reduced atmospheric deposition. - Highlights: {yields} Pied flycatchers were studied in a pollution gradient from a sulfide smelter. {yields} Metal emissions from the smelter have decreased substantially. {yields} Nestling birds still had high metal concentrations in tissues. {yields} Health and survival rates of nestlings were negatively affected. {yields} Recovery of birds is not expected in the near future.

  14. Status of irradiation testing and PIE of MOX (Pu-containing) fuel

    International Nuclear Information System (INIS)

    Dimayuga, F.C.; Zhou, Y.N.; Ryz, M.A.

    1995-01-01

    This paper describes AECL's mixed oxide (MOX) fuel-irradiation and post-irradiation examination (PIE) program. Post-irradiation examination results of two major irradiation experiments involving several (U, Pu)O 2 fuel bundles are highlighted. One experiment involved bundles irradiated to burnups ranging fro 400 to 1200 MWh/kgHe in the Nuclear Power Demonstration (NPD) reactor. The other experiment consisted of several (U, Pu)O 2 bundles irradiated to burnups of up to 500 Mwh/kgHe in the National Research Universal (NRU) reactor. Results of these experiments demonstrate the excellent performance of CANDU MOX fuel. This paper also outlines the status of current MOX fuel irradiation tests, including the irradiation of various (U, Pu)O 2 bundles. The strategic importance of MOX fuel to CANDU fuel-cycle flexibility is discussed. (author)

  15. The issue of ventral versus dorsal approach in bulbar urethral ...

    African Journals Online (AJOL)

    E. Palminteri

    From surgical point of view, the Barbagli Dorsal Grafting by Dor- sal approach [8] gives a good support for the graft; Barbagli stated that his technique offers a wider augmentation than ventral or dorsal grafting using the ventral approach. The good spongiosum covering seems reduce the risk of fistula; in reality there is a ...

  16. Dorsal finger texture recognition: Investigating fixed-length SURF

    DEFF Research Database (Denmark)

    Hartung, Daniel; Kückelhahn, Jesper

    2012-01-01

    We seek to create fixed-length features from dorsal finger skin images extracted by the SURF interest point detector to combine it in the privacy enhancing helper data scheme. The source of the biometric samples is the GUC45 database which features finger vein, fingerprint and dorsal finger skin...

  17. Sunscreen Use on the Dorsal Hands at the Beach

    International Nuclear Information System (INIS)

    Warren, D. B.; Hobbs, J. B.; Jr, R. F. W.; Riahi, R. R.

    2013-01-01

    Since skin of the dorsal hands is a known site for the development of cutaneous squamous cell carcinoma, an epidemiologic investigation was needed to determine if beachgoers apply sunscreen to the dorsal aspect of their hands as frequently as they apply it to other skin sites. Aim. The aim of the current study was to compare the use of sunscreen on the dorsal hands to other areas of the body during subtropical late spring and summer sunlight exposure at the beach. Materials and Methods. A cross-sectional survey from a convenience sample of beachgoers was designed to evaluate responded understanding and protective measures concerning skin cancer on the dorsal hands in an environment with high natural UVR exposure. Results. A total of 214 surveys were completed and analyzed. Less than half of subjects (105, 49%) applied sunscreen to their dorsal hands. Women applied sunscreen to the dorsal hands more than men (55% women versus 40% men, ρ=0.04 ). Higher Fitzpatrick Skin Type respondents were less likely to protect their dorsal hands from ultraviolet radiation (ρ=0.001 ). Conclusions. More public education focused on dorsal hand protection from ultraviolet radiation damage is necessary to reduce the risk for squamous cell carcinomas of the hands.

  18. Effect of Farm on Productive and Reproductive Performance in Sows of Prestice Black-pied Pig

    Directory of Open Access Journals (Sweden)

    Pavel Nevrkla

    2016-01-01

    Full Text Available The aim of the study was to evaluate productive and reproductive performance of Prestice Black‑Pied sows including losses of piglets from birth to weaning in conditions of two farms. The experiment involved one hundred sows of Prestice Black‑Pied pig from the 1st to the 7th parity (50 from farm A and 50 from farm B. The evaluation of productive parameters revealed a highly statistically significant difference (P ≤ 0.001 between gilts of the observed farms in percentage of lean meat. Backfat thickness was 0.19 cm lower in gilts from the farm A, which is a very highly statistically significant difference (P ≤ 0.001. The evaluation of reproductive performance showed, that age at the time of the first insemination and farrowing was significantly higher (P ≤ 0.05 in gilts from the farm A compared to gilts from the farm B by 38 days on average. The analysis also indicates that there was no significant difference in length of gestation, total number of piglets and numbers of live-born and reared piglets between the sows of the evaluated farms. A highly statistically significant difference (P ≤ 0.01 was found in number of stillborn piglets. Interval length was significantly longer (P ≤ 0.05 in sows from the farm A, by 14.29 days. The evaluation of losses of piglets revealed a significant difference (P ≤ 0.05 between the farms in favor of piglets from the farm A.

  19. Degradation of song in a species using nesting holes: the Pied Flycatcher Ficedula hypoleuca

    Directory of Open Access Journals (Sweden)

    Helene M. Lampe

    2004-06-01

    Full Text Available The habitat, but also the nest hole of a hole-nesting species, will degrade the song during transmission. We investigated how the sounds degrade in a sound transmission experiment with the song of the Pied Flycatcher Ficedula hypoleuca (Muscicapidae. Ten different song elements were transmitted to microphones placed inside and outside a nest box. On average, song degradation was much greater inside than outside the nest boxes, especially with respect to excess attenuation and blurring of the song elements. Being inside a nest box therefore strongly reduces a Pied Flycatcher's possibility of detecting and recognizing songs or eavesdropping on singing interactions.O habitat, mas também a cavidade do ninho de uma espécie nidificando em ocos, provoca uma degradação do som durante sua transmissão. Pesquisamos como os sons são degradados num experimento de transmissão sonora usando o canto do pássaro Ficedula hypoleuca (Muscicapidae. Dez elementos diferentes do canto foram enviados para microfones colocados dentro e fora de uma caixa de nidificação. Em média, a degradação do canto foi muito maior dentro do que fora do ninho, particularmente no que diz respeito ao excesso de atenuação e à borrada dos elementos do canto. Estar dentro de uma cavidade de nidificação, portanto, reduz fortemente a capacidade da espécie de detectar e reconhecer cantos ou de interceptar interações vocais.

  20. POPULATION ANALYSIS OF THE LOCAL ENDANGERED PŘEŠTICE BLACK-PIED PIG BREED

    Directory of Open Access Journals (Sweden)

    Emil Krupa

    2015-09-01

    Full Text Available The pedigree analysis of the local endangered Přeštice Black-Pied pig breed (n=19 289 was performed. Animals born within the period 2012-2014 were assumed as the reference population (n=1 374. The pedigree completeness index reached 100% for four generations back. The 100 % of the genetic pool was explained by 66 ancestors. Although all animals of the reference population were inbred, 57% of them had inbreeding less than five percent. Average inbreeding, co-ancestry coefficient and rate of inbreeding reached 4.93%, 13.48% and 1.29% in reference population, respectively. The effective population size calculated by four different methods varied from 32 to 91 animals in 2014. Average generation interval, average family size for sire and dam parents was 2.5, 17.46 and 6.5 animals, respectively. Total number of founders, effective number of founders, effective number of founders’ genomes and effective number of non-founders genomes reached values 299, 98.05, 21.92 and 28.23 founders, respectively. The average genetic diversity (GD loss was 13.71% in reference population. The GD loss has increased within the last three year period mainly due to the random genetic drift (77.6% and by unequal contribution of founders (22.4%. The Preštice Black-Pied breed is highly endangered with GD loss. Mating of closely related animals has to be prevented in breeding and mating program of this breed.

  1. Social suppliers: Exploring the cultural contours of the performance and image enhancing drug (PIED) market among bodybuilders in the Netherlands and Belgium.

    Science.gov (United States)

    van de Ven, Katinka; Mulrooney, Kyle J D

    2017-02-01

    This paper explores the understudied phenomenon of performance and image enhancing drug (PIED) markets by examining the structure and formation of the market for PIEDs among bodybuilders in the Netherlands and Belgium. This article specifically seeks to account for individual reasons and motivations for dealing PIEDs within these bodybuilding subcultures. Understanding illicit PIED markets is important for policy decisions as knowledge on the production and distribution of these substances may assist in designing law enforcement efforts, harm reduction initiatives and treatment options. This article draws on two years of fieldwork in various bodybuilding settings, 47 semi-structured interviews with individuals who are directly or indirectly involved in the PIED market and 64 PIED dealing cases initiated by criminal justice agencies in the Netherlands and Belgium. The data indicates that PIED dealing groups and individuals are often driven by motivations stemming from their social and cultural embeddedness in the bodybuilding subculture. Specifically, these PIED dealers are 'over-socialized' into the structure and culture of bodybuilding and follow the cultural scripts that come with their group affiliation and organization. As a result of the cultural context in which these transactions occur, PIED dealing networks among bodybuilders in the Netherlands and Belgium are more likely to consist of friends or 'friends of friends' tied together by threads of collective meaning found within the bodybuilding subculture. We argue that efforts seeking to explain the structure, formation and motivations of illicit PIED dealing must learn to appreciate how culture mediates structural forces and thereby influences individual and collective action. Policy makers, health care professionals and other relevant parties should consider a plurality of factors (social, economic and cultural) when designing and evaluating PIED-related interventions such as law enforcement efforts, harm

  2. Versatility of the ventral approach in bulbar urethroplasty using dorsal, ventral or dorsal plus ventral oral grafts.

    Science.gov (United States)

    Palminteri, Enzo; Berdondini, Elisa; Fusco, Ferdinando; De Nunzio, Cosimo; Giannitsas, Kostas; Shokeir, Ahmed A

    2012-06-01

    To investigate the versatility of the ventral urethrotomy approach in bulbar reconstruction with buccal mucosa (BM) grafts placed on the dorsal, ventral or dorsal plus ventral urethral surface. Between 1999 and 2008, 216 patients with bulbar strictures underwent BM graft urethroplasty using the ventral-sagittal urethrotomy approach. Of these patients, 32 (14.8%; mean stricture 3.2 cm, range 1.5-5) had a dorsal graft urethroplasty (DGU), 121 (56%; mean stricture 3.7, range 1.5-8) a ventral graft urethroplasty (VGU), and 63 (29.2%; mean stricture 3.4, range 1.5-10) a dorsal plus ventral graft urethroplasty (DVGU). The strictured urethra was opened by a ventral-sagittal urethrotomy and BM graft was inserted dorsally or ventrally or dorsal plus ventral to augment the urethral plate. The median follow-up was 37 months. The overall 5-year actuarial success rate was 91.4%. The 5-year actuarial success rates were 87.8%, 95.5% and 86.3% for the DGU, VGU and DVGU, respectively. There were no statistically significant differences among the three groups. Success rates decreased significantly only with a stricture length of >4 cm. In BM graft bulbar urethroplasties the ventral urethrotomy access is simple and versatile, allowing an intraoperative choice of dorsal, ventral or combined dorsal and ventral grafting, with comparable success rates.

  3. Efecto del hialuronato de zinc sobre las úlceras en pacientes con diabetes

    Directory of Open Access Journals (Sweden)

    Fernando Ramos Cuevas

    Full Text Available Contexto: La úlcera en el pie diabético es una de las principales complicaciones de la diabetes en extremidades bajas. Del 50 al 70% de las amputaciones en extremidades bajas se realizan a pacientes con diabetes. El hialuronato de zinc ha sido probado en el tratamiento de las úlceras diabéticas del pie con resultados prometedores. Objetivo general: Determinar el grado de eficacia del hialuronato de zinc en la curación de úlceras del pie diabético. Diseño: Ensayo terapéutico abierto al azar. Se les dio seguimiento a los pacientes durante un período de doce semanas de junio a diciembre de 2004. Ubicación: Centro de cuidado terciario. Clínica del Pie Diabético. Pacientes: Fueron seleccionados por muestreo consecutivo cincuenta pacientes con diabetes tipo 2 con úlcera en pie, de ambos sexos y con edades entre los 40 y los 80 años y sin una isquemia más baja de la extremidad. Veinticinco de ellos fueron asignados aleatoriamente al grupo del hialuronato de zinc y el resto al grupo de control (tratamiento convencional. La distribución por sexo de género fue similar en ambos grupos, once del femenino (44% y 14 del masculino (56%. La edad promedio en el grupo de la combinación del ácido hialurónico y zinc fue 56,76 ± 8,78 y en el convencional 60,12 ± 8,42, NS. ningún paciente del grupo de hialuronato de zinc abandonó o fue retirado durante el período del estudio. Un paciente del grupo de control falleció. Intervención: El hialuronato de zinc fue aplicado una vez al día en la superficie de la úlcera después de limpiarla con la solución fisiológica salina. Medida principal del resultado: La eficacia del hialuronato de zinc fue determinada por las semanas que se requirieron para conseguir el cierre completo de la úlcera con el tejido fino epitelial (tiempo curativo medio. Material y métodos: Ensayo clínico controlado. Pacientes con úlceras propias del pie diabético. 1 de julio al 30 de septiembre de 2004, 25 pacientes

  4. A satisfação do cliente : estudo do caso do franchising de fast-food King Pie na Cidade de Maputo em Moçambique

    OpenAIRE

    Ramos, Vânia Raquel Raimundo

    2014-01-01

    Dissertação de Mestrado em Gestão/MBA apresentada à Universidade Aberta O presente trabalho tem por objectivo central, estudar a satisfação dos clientes da empresa King Pie na Cidade de Maputo. O King Pie é uma cadeia sul-africana de fast-food, que em Moçambique opera em regime de franchising, estando presente no mercado local desde o ano de 2004. Neste momento, o King Pie dispõe quatro (4) estabelecimentos localizados na Cidade de Maputo com dois (2) investidores no país que detêm o direi...

  5. Factores de riesgo en diabetes mellitus y pie diabético: un enfoque hacia la prevención primaria

    Directory of Open Access Journals (Sweden)

    Análida E Pinilla

    2013-08-01

    Full Text Available Objetivo: revisar la literatura sobre factores de riesgo asociados a diabetes mellitus y sus complicaciones, las estrategias de prevención y la importancia de programas interdisciplinarios para mejorar la calidad de vida. Fuente de datos: búsqueda de la literatura científica publicada en español e inglés, en bases de datos como Medline, SciELO y otras de la Universidad Nacional de Colombia mediante palabras clave; además, revisión de libros y consensos afines con el tema. Selección de estudios: se revisaron los títulos y resúmenes de documentos para seleccionar las publicaciones originales, así como las más representativas con relación a prevención primaria y educación. Extracción de datos: la literatura se clasificó y organizó de acuerdo con el tema principal y la estructura del artículo. Síntesis de datos: se inició un análisis crítico para ordenar y sintetizar los avances relacionados con los siguientes ítems: factores de riesgo para diabetes mellitus, epidemiología, pie diabético, educación, prevención primaria y estilos de vida relacionados con ejercicio y alimentación. Conclusión: el impacto de la diabetes mellitus y sus complicaciones en la salud de los individuos hace necesario establecer políticas de salud pública de prevención primaria, para minimizar el progreso de esta epidemia. Es esencial instaurar y fortalecer programas educativos orientados por profesionales de la salud, además de implementar la formación en diabetes mellitus en los currículos de pregrado y posgrado del área de la salud.

  6. Efectividad a corto plazo del vendaje neuromuscular y vendaje funcional en la corrección del retropié pronado y supinado

    OpenAIRE

    Luque-Suárez, Alejandro

    2011-01-01

    La utilización de métodos de corrección articular de las dealineaciones del pie en el plano frontal dentro del campo de la medicina, fisioterapia o la podología se encuentra ampliamente documentado y ha sido comúnmente empleado. Dentro de estos dispositivos se encuentran el vendaje funcional y el vendaje neuromuscular (también denominado kinesiotaping, medical taping, neurotaping o balance taping). Objetivos: 1.Comparar la efectividad del vendaje funcional y el vendaje neuromuscular en la...

  7. Estimación del diámetro, altura y volumen a partir del tocón para especies forestales de Durango

    OpenAIRE

    Quiñónez Barraza, Gerónimo; Cruz Cobos, Francisco; Vargas Larreta, Benedicto; Hernández, Francisco Javier

    2012-01-01

    Cuando una masa forestal ha sido aprovechada mediante un programa de manejo y solo se tiene como evidencia las dimensiones de los tocones, es posible estimar a través de relaciones alométricas el diámetro y la altura, así como el volumen de los árboles en pie. En el presente trabajo se describe un experimento en el que se ajustaron 12 modelos matemáticos para predecir el diámetro normal, la altura total y el volumen del fuste, a partir del diámetro del tocón para Pinus arizonica , P. ayacahui...

  8. A Comparative Study of Dorsal Buccal Mucosa Graft Substitution Urethroplasty by Dorsal Urethrotomy Approach versus Ventral Sagittal Urethrotomy Approach

    Directory of Open Access Journals (Sweden)

    Mrinal Pahwa

    2013-01-01

    Full Text Available Objectives. To compare the outcome of dorsal buccal mucosal graft (BMG substitution urethroplasty by dorsal urethrotomy approach with ventral urethrotomy approach in management of stricture urethra. Methods and Materials. A total of 40 patients who underwent dorsal BMG substitution urethroplasty were randomized into two groups. 20 patients underwent dorsal onlay BMG urethroplasty as described by Barbagli, and the other 20 patients underwent dorsal BMG urethroplasty by ventral urethrotomy as described by Asopa. Operative time, success rate, satisfaction rate, and complications were compared between the two groups. Mean follow-up was 12 months (6–24 months. Results. Ventral urethrotomy group had considerably lesser operative time although the difference was not statistically significant. Patients in dorsal group had mean maximum flow rate of 19.6 mL/min and mean residual urine of 27 mL, whereas ventral group had a mean maximum flow rate of 18.8 and residual urine of 32 mL. Eighteen out of twenty patients voided well in each group, and postoperative imaging study in these patients showed a good lumen with no evidence of leak or extravasation. Conclusion. Though ventral sagittal urethrotomy preserves the blood supply of urethra and intraoperative time was less than dorsal urethrotomy technique, there was no statistically significant difference in final outcome using either technique.

  9. A Comparative Study of Dorsal Buccal Mucosa Graft Substitution Urethroplasty by Dorsal Urethrotomy Approach versus Ventral Sagittal Urethrotomy Approach.

    Science.gov (United States)

    Pahwa, Mrinal; Gupta, Sanjeev; Pahwa, Mayank; Jain, Brig D K; Gupta, Manu

    2013-01-01

    Objectives. To compare the outcome of dorsal buccal mucosal graft (BMG) substitution urethroplasty by dorsal urethrotomy approach with ventral urethrotomy approach in management of stricture urethra. Methods and Materials. A total of 40 patients who underwent dorsal BMG substitution urethroplasty were randomized into two groups. 20 patients underwent dorsal onlay BMG urethroplasty as described by Barbagli, and the other 20 patients underwent dorsal BMG urethroplasty by ventral urethrotomy as described by Asopa. Operative time, success rate, satisfaction rate, and complications were compared between the two groups. Mean follow-up was 12 months (6-24 months). Results. Ventral urethrotomy group had considerably lesser operative time although the difference was not statistically significant. Patients in dorsal group had mean maximum flow rate of 19.6 mL/min and mean residual urine of 27 mL, whereas ventral group had a mean maximum flow rate of 18.8 and residual urine of 32 mL. Eighteen out of twenty patients voided well in each group, and postoperative imaging study in these patients showed a good lumen with no evidence of leak or extravasation. Conclusion. Though ventral sagittal urethrotomy preserves the blood supply of urethra and intraoperative time was less than dorsal urethrotomy technique, there was no statistically significant difference in final outcome using either technique.

  10. SPINAL DEFORMITIES AFTER SELECTIVE DORSAL RHIZOTOMY

    Directory of Open Access Journals (Sweden)

    PATRICIO PABLO MANZONE

    Full Text Available ABSTRACT Objective: Selective dorsal rhizotomy (SDR used for spasticity treatment could worsen or develop spinal deformities. Our goal is to describe spinal deformities seen in patients with cerebral palsy (CP after being treated by SDR. Methods: Retrospective study of patients operated on (SDR between January/1999 and June/2012. Inclusion criteria: spinal Rx before SDR surgery, spinography, and assessment at follow-up. We evaluated several factors emphasizing level and type of SDR approach, spinal deformity and its treatment, final Risser, and follow-up duration. Results: We found 7 patients (6 males: mean age at SDR 7.56 years (4.08-11.16. Mean follow-up: 6.64 years (2.16-13, final age: 14.32 years (7.5-19. No patient had previous deformity. GMFCS: 2 patients level IV, 2 level III, 3 level II. Initial walking status: 2 community walkers, 2 household walkers, 2 functional walkers, 1 not ambulant, at the follow-up, 3 patients improved, and 4 kept their status. We found 4 TL/L laminotomies, 2 L/LS laminectomies, and 1 thoracic laminectomy. Six spinal deformities were observed: 2 sagittal, 3 mixed, and 1 scoliosis. There was no association among the type of deformity, final gait status, topographic type, GMFCS, age, or SDR approach. Three patients had surgery indication for spinal deformity at skeletal maturity, while those patients with smaller deformities were still immature (Risser 0 to 2/3 although with progressive curves. Conclusions: After SDR, patients should be periodically evaluated until they reach Risser 5. The development of a deformity does not compromise functional results but adds morbidity because it may require surgical treatment.

  11. Effect of shed rooftype and babassu pie on the productive characteristics of meat quails

    Directory of Open Access Journals (Sweden)

    Jordane de Oliveira Borges

    2017-08-01

    Full Text Available We aimed to evaluate the effects of shed roof(SR typeand the inclusion of babassu pie (BP in rations on the productive characteristics ofmeat quailsfrom days 14 to 28 and days14 to 40. We studied 896 meatquails. The experimental design was completely randomized with a 4x4 factorial arrangement, using four types of shedroofs (fiber cement, ceramic, straw, and painted fiber cement and four rations (with 0, 5, 10, and 15% inclusion of babassu pie. The performance variables evaluated from 14 to 28 and 14 to 40 days included food intake (FI, g/bird, mean weight gain (WG, g/bird, food conversion (FC, g/g, mean live weight on day 28 (MW28, g/bird, mean live weight on day 40 (MW40, g/bird, and energy efficiency (EF; g Mcal. After slautherthe birds on day 40, we measured the carcass weight (CW and the carcass yield (CY, %, obtained for the breast (BY, legs (LGY, and wings (WINGY. We also obtained the relative weight of the heart (HRW, liver (LRW, gizzard (GRW, and intestine (IRW. To compare the economic efficiency between the experimental rations, we analyzed the cost of ration per kg of carcass (CC and determined the gross margin (GM. Between day 14 and day 28, we found that the use of SR influenced the FI28, WG28, and the MW28 of the quails (p 0.05, but it linearly improved WG28, FC28, MW28, and EF28. Between days 14 and 40, we found that SR influenced the WG40, FC40, MW40, and EF40 of the quails (p < 0.05 and that a BP increased the FI40, WG40, and MW40 in a quadratic manner. SR and BP did not affect the CW, BY, WINGY, LGY, HRW, LRW,or IRW. However, BP influenced MGRW, which increased linearly with the inclusion of BP. We concluded that a ceramic roof provides better environmental conditions than do other shed roofs. The inclusion of BP improved the performance characteristics, and it was technically feasible to include up to 15% BP in the rations of meat quails. Based on the current cost analysis, however, the inclusion of BP is economically

  12. Dorsal onlay graft bulbar urethroplasty using buccal mucosa

    African Journals Online (AJOL)

    G. Barbagli

    2015-12-02

    Dec 2, 2015 ... promote the transformation of the urethral mucosa plate into a tube, according to ... Allen stirrups and sequential inflatable compression sleeves. Figure 2 .... the ventral, dorsal or lateral surface of the urethra, we investigated if.

  13. Effect of the enriched filter pie with natural phosphate and microorganisms on soil and plant in a Vermelho-Distrófico Latossolo

    Directory of Open Access Journals (Sweden)

    Leónides Castellanos González

    2016-03-01

    Full Text Available The objective of the research was to evaluate the use of filter pie and phosphate rock enriched with biofertilizer microorganisms on the population of microorganisms and phosphorus tenor in the soil and on plants. The experiment was conducted in a vegetation house with corn plants with Latossolo Red-Distrófico, containing seven treatments disposed in an entirely randomized design, where the treatments were: soil samples and filter pie with additions of phosphate of Araxá rock enriched with microorganisms coming from Biopack (1, Embrafos (2 and Azotofos (3, and without enrichment with microorganisms (4, and three controls, soil just with filter pie (5, soil just with phosphate rock (6 and only soil (7, with three repetitions. Height, stem diameter and number of leaves for plants were evaluated at 14, 28 and 42 days. At the 45 days the dry matters of leafs and roots were evaluated, as the same as populations of the microorganisms and phosphorus tenor in the soil and in the aerial part of the plant. The tenor of soluble phosphorus in the soil and accumulated phosphorous in the aerial part of corn plan were increased by the treatments with filter pie but not higher with filter pie enriched with biofertilizers, so its use isn’t justified. The pie treatments increase the fungus, total and solubilizers bacterial populations in the soil, provoking an increase of the height, diameter, number of leaves and dry matter of corn plants in a Red-Distrófico Latossolo.

  14. Biomecánica del vendaje funcional preventivo de tobillo en deportes de colaboración-oposición

    OpenAIRE

    Meana Riera, Marta

    2004-01-01

    La aplicación del vendaje funcional de tobillo como método preventivo de los esguinces, durante los entrenamientos y las competiciones, está muy extendida en la práctica diaria, sobre todo en fútbol, baloncesto, balonmano y voleibol. En el estudio, que abre nuevas líneas de investigación en las patologías del pie del deportista, se realiza un profundo análisis de la eficacia de estos vendajes sanos y de sus efectos sobre el rendimiento deportivo y la biomecánica del tobillo. Actividad Físi...

  15. Relating the effects of protein type and content in increased-protein cheese pies to consumers' perception of satiating capacity.

    Science.gov (United States)

    Marcano, J; Varela, P; Fiszman, S

    2015-02-01

    Since proteins have been shown to have the highest satiation-inducing effects of all the macronutrients, increasing the protein level is one of the main strategies for designing foods with enhanced satiating capacity. However, few studies analyze the effect that protein addition has on the texture and flavor characteristics of the target food item to relate it to the expected satiating capacity it elicits. The present work studied cheese pies with three levels of soy and whey proteins. Since the protein level altered the rheological behavior of the batters before baking and the texture of the baked pies, the feasibility of adding several protein levels for obtaining a range of final products was investigated. A check-all-that-apply questionnaire containing 32 sensory and non-sensory characteristics of the samples was given to consumers (n = 131) who also scored the perceived samples' satiating capacity. The results showed that the type and content of protein contributed distinctive sensory characteristics to the samples that could be related to their satiating capacity perception. Harder and drier samples (high protein levels) were perceived as more satiating with less perceptible sweet and milky cheese pie characteristic flavors. Soy contributed an off-flavour. These results will contribute to a better understanding of the interrelation of all these factors, aiding the development of highly palatable solid foods with enhanced satiating capacities.

  16. The Perceived Invalidation of Emotion Scale (PIES): Development and psychometric properties of a novel measure of current emotion invalidation.

    Science.gov (United States)

    Zielinski, Melissa J; Veilleux, Jennifer C

    2018-05-24

    Emotion invalidation is theoretically and empirically associated with mental and physical health problems. However, existing measures of invalidation focus on past (e.g., childhood) invalidation and/or do not specifically emphasize invalidation of emotion. In this article, the authors articulate a clarified operational definition of emotion invalidation and use that definition as the foundation for development of a new measure of current perceived emotion invalidation across a series of five studies. Study 1 was a qualitative investigation of people's experiences with emotional invalidation from which we generated items. An initial item pool was vetted by expert reviewers in Study 2 and examined via exploratory factor analysis in Study 3 within both college student and online samples. The scale was reduced to 10 items via confirmatory factor analysis in Study 4, resulting in a brief but psychometrically promising measure, the Perceived Invalidation of Emotion Scale (PIES). A short-term longitudinal investigation (Study 5) revealed that PIES scores had strong test-retest reliability, and that greater perceived emotion invalidation was associated with greater emotion dysregulation, borderline features and symptoms of emotional distress. In addition, the PIES predicted changes in relational health and psychological health over a 1-month period. The current set of studies thus presents a psychometrically promising and practical measure of perceived emotion invalidation that can provide a foundation for future research in this burgeoning area. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  17. Prevalencia del juanete de sastre y quinto dedo adducto varo en el baile flamenco profesional. Prevalence of tailor's bunion and fifth toe adductus varus in professional flamenco dancing.

    OpenAIRE

    Nadia Salti; Gabriel Domínguez; Pedro V. Munuera; José Manuel Castillo; Cristina Algaba

    2013-01-01

    El Juanete de Sastre es una deformidad adquirida que afecta al quinto metatarsiano y quinto dedo del pie. Se caracteriza por una prominencia lateral en la cabeza del quinto metatarsiano, con una marcada desviación medial del quinto dedo y una desviación lateral del V metatarsiano. De origen multifactorial, hablamos de una etiología micro traumática influida por posturas viciosas en dinámica, estática o sedente, por la influencia del calzado y la presencia de alteraciones biomecánicas de la ex...

  18. Functional connectivity of the dorsal striatum in female musicians

    Directory of Open Access Journals (Sweden)

    Shoji eTanaka

    2016-04-01

    Full Text Available The dorsal striatum (caudate/putamen is a node of the cortico-striato-pallido-thalamo-cortical (CSPTC motor circuit, which plays a central role in skilled motor learning, a critical feature of musical performance. The dorsal striatum receives input from a large part of the cerebral cortex, forming a hub in the cortical-subcortical network. This study sought to examine how the functional network of the dorsal striatum differs between musicians and nonmusicians.Resting state functional magnetic resonance imaging (fMRI data were acquired from female university students majoring in music and nonmusic disciplines. The data were subjected to graph theoretical analysis and functional connectivity analysis. The graph theoretical analysis of the entire brain revealed that the degree, which represents the number of connections, of the bilateral putamen was significantly lower in musicians than in nonmusicians. The functional connectivity analysis indicated that compared with nonmusicians, musicians had significantly decreased connectivity between the left putamen and bilateral frontal operculum and between the left caudate nucleus and cerebellum. In conclusion, compared with nonmusicians, female musicians have a smaller functional network of the dorsal striatum, with decreased connectivity. These data are consistent with previous anatomical studies reporting a reduced volume of the dorsal striatum in musicians and ballet dancers. To the best of our knowledge, this is the first study suggesting that long-term musical training results in a less extensive or selective functional network of the dorsal striatum.

  19. Tres caixes plenes d'art: Tàpies, Miró i Picasso

    Directory of Open Access Journals (Sweden)

    Lourdes Martín-Herrero

    2009-10-01

    Full Text Available Tres caixes plenes d’art és el resultat d’un projecte dut a terme durant cinc mesos del curs escolar 2008/2009, gràcies a l’adjudicació d’una llicència d’estudis retribuïda pel Departament d’Educació de la Generalitat de Catalunya. El punt de partida en les tres caixes és l’art a l’escola, en concret en el parvulari. L’art com a epicentre del qual es teixeix una xarxa amb tots els aspectes del currículum, que conformen la globalitat dels nens i nenes com a persones. Així, a grans trets, podríem dir que, amb el conjunt del treball dels tres artistes esmentats i el dels tres eixos temàtics triats (les textures i els materials de l’entorn, els símbols i els colors, els sentiments i les emocions, al llarg del cicle d’educació infantil, aprofundim en la descoberta de l’entorn, en la comunicació i llenguatges i en la descoberta d’un mateix i dels altres.

  20. Placental immune editing switch (PIES): learning about immunomodulatory pathways from a unique case report

    Science.gov (United States)

    Bronchud, Miguel H.; Tresserra, Francesc; Xu, Wenjie; Warren, Sarah; Cusido, Maite; Zantop, Bernat; Zenclussen, Ana Claudia; Cesano, Alessandra

    2016-01-01

    The hypothesis of this work is that, in order to escape the natural immune surveillance mechanisms, cancer cells and the surrounding microenvironment might express ectopically genes that are physiologically present in the placenta to mediate fetal immune-tolerance. These natural “placental immune-editing switch” mechanisms (PIES) may represent the result of millions of years of mammalian evolution developed to allow materno-fetal tolerance. Here, we introduce genes of the immune regulatory pathways that are either similarly over- or under-expressed in tumor vs normal tissue. Our analysis was carried out in primary breast cancer with metastatic homolateral axillary lymph nodes as well as placenta tissue (both uterine decidual tissue and term placenta tissue) from a pregnant woman. Gene expression profiling of paired non-self and self tissues (i.e. placenta/uterus; breast cancer/normal breast tissue; metastatic lymphnode/normal lymphnode tissue) was performed using the PanCancer Immune gene panel, a 770 Nanostring gene expression panel. Our findings reveal overlapping in specific immune gene expression in placenta and cancer tissue, suggesting that these genes might play an important role in maintaining immune tolerance both physiologically (in the placenta) and pathologically (in the cancer setting). PMID:27852037

  1. Inferred residual gaps for IFA-527 rods, compared to PIE measurements

    International Nuclear Information System (INIS)

    Lanning, D.D.

    1983-05-01

    The NRC-sponsored assembly IFA-527 contained six xenon-filled rods, each instrumented with fuel thermocouples at each end. Five of the six rods contained stable UO 2 fuel pellets with a fabricated diametral gap size of 230 microns. The rods were unique among instrumented test rods in that their lifetime peak powers were quite low (less than 20 kW/m). The assembly was removed at low exposure (about 2 MWd/kgM) due to pressure seal failures. The prefailure measured fuel temperatures in the five identical rods were quite similar, and indicated an effective fuel relocation of about 30 to 35 percent of the as-fabricated gap. Examination of rod cross sections in PIE, however, reveals virtually no reduction in the as-fabricated gap. In an attempt to reconcile these two observations, it is demonstrated that pellet eccentricity could account for the inferred effective relocation for these xenon-filled rods. That analysis is extended to an estimate of the proper effective relocation value for low-powered He-filled rods

  2. Sex-Specific Associations between Telomere Dynamics and Oxidative Status in Adult and Nestling Pied Flycatchers.

    Science.gov (United States)

    López-Arrabé, Jimena; Monaghan, Pat; Cantarero, Alejandro; Boner, Winnie; Pérez-Rodríguez, Lorenzo; Moreno, Juan

    Oxidative stress can contribute to an acceleration of telomere erosion, leading to cellular senescence and aging. Increased investment in reproduction is known to accelerate senescence, generally resulting in reduced future reproductive potential and survival. To better understand the role played by oxidative status and telomere dynamics in the conflict between maintenance and reproduction, it is important to determine how these factors are related in parents and their offspring. We investigated the relationship between oxidative status and telomere measurements in pied flycatchers (Ficedula hypoleuca). Total antioxidant status (TAS) in plasma, total levels of glutathione in red blood cells (RBCs), and oxidative damage in plasma lipids (malondialdehyde [MDA]) were assessed in both parents and nestlings. Telomeres were measured in RBCs in adults. Our results showed sex differences in oxidative variables in adults that are likely to be mediated by sex steroids, with testosterone and estrogens increasing and reducing, respectively, the production of reactive oxygen and nitrogen species. We found a negative association between telomere length (TL) and MDA in adults in the previous season. Moreover, TL was positively associated with TAS in females, while telomere shortening (ΔTL) correlated positively with MDA in males in the current year. These associations could be reflecting differences between sexes in reproductive physiology. We found a positive correlation between parental ΔTL and nestling MDA, an example of how parental physiological aging could affect offspring quality in terms of oxidative stress that highlights the constraints imposed by higher rates of ΔTL during reproduction and rearing.

  3. Does the Circular Economy Grow the Pie? The Case of Rebound Effects From Smartphone Reuse

    Directory of Open Access Journals (Sweden)

    Tamar Makov

    2018-05-01

    Full Text Available The environmental benefits of the circular economy (CE are often taken for granted. There are, however, reasons to believe that rebound effects may counteract such benefits by increasing overall consumption or “growing the pie.” In this study, we focus on two main rebound mechanisms: (1 imperfect substitution between “re-circulated” (recycled, reused, etc. and new products and (2 re-spending due to economic savings. We use the case study of smartphone reuse in the US to quantify, for the first time, rebound effects from reuse. Using a combination of life cycle assessment, sales statistics, consumer surveying, consumer demand modeling, and environmentally-extended input-output analysis, we quantify the magnitude of this rebound effect for life-cycle greenhouse gas emissions. We find a rebound effect of 29% on average, with a range of 27–46% for specific smartphone models. Moreover, when exploring how rebound might play out in other regions and under different consumer behavior patterns, we find that rebound effects could be higher than 100% (backfire effect. In other words, we estimate that about one third, and potentially the entirety, of emission savings resulting from smartphone reuse could be lost due to the rebound effect. Our results thus suggest that there are grounds to challenge the premise that CE strategies, and reuse in particular, always reduce environmental burdens.

  4. El sistema de cierre asistido al vacío en el tratamiento del pie diabético avanzado

    OpenAIRE

    Dzieciuchowicz, L. (Lukasz); Espinosa, G. (Gaudencio); Grochowicz, L. (Lukasz)

    2009-01-01

    Deep diabetic foot lesions pose an enormous therapeutic problem. The purpose of this study was to present the experience of the use of vacuum assisted closure (VAC) in the treatment of advanced and complicated diabetic foot lesions. MATERIAL AND METHODS: Five cases of advanced diabetic foot that were treated with VAC were prospectively studied. Three patients were diagnosed with renal failure, including one with renal transplant, who were receiving...

  5. Conocimientos, destrezas y conductas ante el cuidado de los pies en un grupo de amputados diabéticos Knowledge, abilities and behaviours in foot care in a group of diabetic amputees

    Directory of Open Access Journals (Sweden)

    Rolando Suárez Pérez

    2001-08-01

    Full Text Available Se conoce que el cuidado de los pies, uno de los mayores retos en la atención a personas diabéticas, no se enfoca adecuadamente en las consultas de rutina por lo cual se pierde la función preventiva de las complicaciones en miembros inferiores y su máxima manifestación: la amputación. Para lograr un acercamiento a este problema el trabajo tuvo como objetivo determinar la información y las orientaciones prácticas que tenía un grupo de pacientes diabéticos que sufrían una amputación en el momento del estudio. Se entrevistaron 105 diabéticos hospitalizados en las salas de Angiología de 2 hospitales generales. La entrevista se dirigió a recoger información que permitiera caracterizar el actual proceso de amputación y determinar la información y las orientaciones prácticas que sobre el cuidado de los pies en general y su proceso particular de amputación, habían recibido estas personas. Se encontró que el 62,5 % del grupo no revisaba periódicamente sus pies y el 42,4 % no identificó como peligrosas algunas prácticas caseras ante callosidades, cortado de uñas, etc. Solamente el 29,5 % pudo identificar 1 ó 2 cuidados prácticos de los pies. Se comprobó que no habían recibido información práctica al respecto y que en el 52,4 %, el inicio de la presente complicación fue por descuido, errores de conducta o ignorancia de cómo proceder. Se concluyó que una intervención educativa podría haber contribuido sustancialmente a reducir las amputacionesIt is known that foot care, one of the biggest challenges for diabetic persons care, is not adequately approached in regular appointments and that is why the function of preventing the occurrence of complications in lower limbs and its top manifestation, that is, amputation, is lost. To address this problem, the present paper was aimed at determining the information and practical orientations received by a group of diabetic patients suffering from amputation at the time of the study

  6. IMPLICACIONES TERRITORIALES DE UNA GRAN OBRA HIDRÁULICA: EL EMBALSE DEL TRANCO (CABECERA DEL GUADALQUIVIR

    Directory of Open Access Journals (Sweden)

    Eduardo Araque Jiménez

    2012-01-01

    Full Text Available Situado en la cabecera del Guadalquivir, el embalse del Tranco fue durante muchos años el de mayor capacidad de almacenamiento de agua de toda Andalucía. Sus aportaciones resultaron fundamentales para el sostenimiento del regadío en el gran valle bético, al tiempo que con sus aguas pudo generarse una parte de la energía eléctrica que se precisaba para la modernización del aparato productivo andaluz y la mejora de las condiciones de vida en multitud de hogares en el valle del Guadalquivir. Frente a estas perspectivas tan halagüeñas, las aguas embalsadas en el Tranco apenas tuvieron repercusiones socioeconómicas positivas para la Sierra de Segura. Las expropiaciones masivas a las que dio origen tanto la construcción del embalse como la repoblación forestal que lo acompañó, propiciaron la emigración masiva de centenares de vecinos, muchas veces en condiciones de extrema precariedad. Por otro lado, las aguas del Tranco nunca se utilizaron para la expansión del regadío por algunos de los fértiles valles próximos al embalse, ni la electricidad generada a pie de presa llegó a los hogares serranos, que siguieron careciendo de este servicio durante muchos años.

  7. Perfil antropométrico en función del estado nutricional de niños con discapacidad intelectual

    OpenAIRE

    Cossio, Marco; Vidal, Rubén; Lagos, Juan; Gómez, Rossana

    2015-01-01

    Para este estudio se estudiaron 49 niños y adolescentes con discapacidad intelectual (30 hombres y 19 mujeres) de una escuela de educación especial. Se evaluaron el peso, la estatura, la altura troncocefálica, y la longitud del antebrazo y el pie. El cálculo del estado nutricional permitió establecer categorías nutricionales: bajo peso, peso normal y exceso de peso.

  8. Crecimiento longitudinal posnatal del primer metatarsiano. [Longitudinal postnatal growth of the first metatarsal bone

    Directory of Open Access Journals (Sweden)

    Julio J. Masquijo

    2014-10-01

    Full Text Available Introducción: si bien el crecimiento prenatal y posnatal del pie ha sido documentado hace varios años, el crecimiento longitudinal del primer metatarsiano en particular no ha sido estudiado previamente. El objetivo del estudio es determinar el patrón de crecimiento longitudinal posnatal de este hueso y compararlo con el del pie y los huesos largos del miembro inferior. Materiales y Métodos: mediante una búsqueda informatizada, se identificaron pacientes <18 años de edad con radiografías informadas como “normal” por el radiólogo. Se analizó una muestra de 886 pacientes divididos en 18 grupos según la edad (0-11 meses, 1 año, 2 años, etc. y el sexo. El análisis de las imágenes se realizó con un software de imágenes Kodak Carestream PACS. Resultados: el largo promedio en el primer grupo fue de 19,91 mm (3,20; 15,22-25,62. El largo promedio en el último grupo fue de 66,13 mm (5,33; 52,50-77,18. La tasa de crecimiento anual fue de 2,71 mm. La edad promedio al momento del cierre de la fisis fue de 14.85 años (± 1.64 para los varones y 14.77 años (± 3.63 para las niñas. Conclusión: el crecimiento del primer metatarsiano acompaña el crecimiento longitudinal del pie, pero no el de los huesos largos del miembro inferior. Las curvas de crecimiento del primer metatarsiano descritas en este artículo pueden ser aplicadas en patologías que afectan el desarrollo del pie o que requieren cirugía de corrección sobre el primer metatarsiano, o se las puede emplear como estándar de referencia en futuros estudios.

  9. Transferencia microquirúrgica hemipulpar del hallux en la reconstrucción del pulgar

    Directory of Open Access Journals (Sweden)

    José-Manuel Rodríguez-Vegas

    Full Text Available Introducción y Objetivo. La transferencia hemipulpar del hallux permite excelentes reconstrucciones de pulgar porque ofrece tejidos blandos de alta calidad, contorno pulpar casi normal y recuperación sensitiva satisfactoria sin necesidad de reorientación cortical. Además, a diferencia de colgajos locales y regionales, evita la agresión adicional a una mano ya lesionada, optimizando así el período de rehabilitación y el resultado final. El artículo revisa la experiencia del autor en la técnica y compara el procedimiento con otras opciones reconstructivas. Material y Método. Realizamos una revisión retrospectiva de 16 pacientes sometidos a transferencia hemipulpar del hallux en el período 2007-2013. Todos los pacientes fueron varones, con una edad media de 34 años y una alta demanda funcional (trabajadores manuales con traumatismo laboral. La técnica fue indicada en defectos mayores del 50% de la superficie pulpar del pulgar en pacientes sin factores de riesgo asociados relevantes. En 3 de los casos el defecto pulpar asoció un defecto óseo de falange distal de tamaño suficiente para aconsejar la transferencia combinada osteo-pulpar. Resultados. Quince de los 16 colgajos sobrevivieron sin incidencias postoperatorias. Un colgajo sufrió trombosis arterial con retirada del colgajo y cirugía adicional de cobertura. En 2 pacientes se realizó revisión estética del colgajo de manera diferida. Excepto en el caso fallido, todos los pacientes volvieron a su actividad laboral previa con excelente recuperación funcional de la mano. El cierre de la zona donante se realizó mediante cierre directo (12 pacientes o injerto cutáneo (4 pacientes. Ninguno de los pacientes, independientemente del tipo de cierre del defecto en el pie, refirió problemas en la deambulación o apariencia estética del pie. Conclusiones. La reconstrucción de defectos pulpares del pulgar mediante transferencia hemipulpar del hallux permite un excelente resultado

  10. Emergent properties during dorsal closure in Drosophila morphogenesis

    International Nuclear Information System (INIS)

    Peralta, X G; Toyama, Y; Edwards, G S; Kiehart, D P

    2008-01-01

    Dorsal closure is an essential stage of Drosophila development that is a model system for research in morphogenesis and biological physics. Dorsal closure involves an orchestrated interplay between gene expression and cell activities that produce shape changes, exert forces and mediate tissue dynamics. We investigate the dynamics of dorsal closure based on confocal microscopic measurements of cell shortening in living embryos. During the mid-stages of dorsal closure we find that there are fluctuations in the width of the leading edge cells but the time-averaged analysis of measurements indicate that there is essentially no net shortening of cells in the bulk of the leading edge, that contraction predominantly occurs at the canthi as part of the process for zipping together the two leading edges of epidermis and that the rate constant for zipping correlates with the rate of movement of the leading edges. We characterize emergent properties that regulate dorsal closure, i.e., a velocity governor and the coordination and synchronization of tissue dynamics

  11. Meaningful call combinations and compositional processing in the southern pied babbler

    Science.gov (United States)

    Engesser, Sabrina; Ridley, Amanda R.; Townsend, Simon W.

    2016-01-01

    Language’s expressive power is largely attributable to its compositionality: meaningful words are combined into larger/higher-order structures with derived meaning. Despite its importance, little is known regarding the evolutionary origins and emergence of this syntactic ability. Although previous research has shown a rudimentary capability to combine meaningful calls in primates, because of a scarcity of comparative data, it is unclear to what extent analog forms might also exist outside of primates. Here, we address this ambiguity and provide evidence for rudimentary compositionality in the discrete vocal system of a social passerine, the pied babbler (Turdoides bicolor). Natural observations and predator presentations revealed that babblers produce acoustically distinct alert calls in response to close, low-urgency threats and recruitment calls when recruiting group members during locomotion. On encountering terrestrial predators, both vocalizations are combined into a “mobbing sequence,” potentially to recruit group members in a dangerous situation. To investigate whether babblers process the sequence in a compositional way, we conducted systematic experiments, playing back the individual calls in isolation as well as naturally occurring and artificial sequences. Babblers reacted most strongly to mobbing sequence playbacks, showing a greater attentiveness and a quicker approach to the loudspeaker, compared with individual calls or control sequences. We conclude that the sequence constitutes a compositional structure, communicating information on both the context and the requested action. Our work supports previous research suggesting combinatoriality as a viable mechanism to increase communicative output and indicates that the ability to combine and process meaningful vocal structures, a basic syntax, may be more widespread than previously thought. PMID:27155011

  12. Possible roles for corticosterone and critical size in the fledging of nestling pied flycatchers.

    Science.gov (United States)

    Kern, M; Bacon, W; Long, D; Cowie, R J

    2001-01-01

    Our study was designed to see whether corticosterone (B) rises abruptly in the blood of nestling pied flycatchers (Ficedula hypoleuca) at the time they fledge, as reported recently for kestrels, and if so, why. We measured the growth and blood levels of B and selected nutrients of nestlings in broods of five, seven, and nine chicks during 1998 and 1999. In half of the broods, we clipped selected wing and tail feathers of both parents with the intention of making it more difficult for them to provide their chicks with food. We collected blood samples when the chicks were six to 10 d old (period of rapid growth) and 15 d of age or older (0-5 d before fledging). B increased substantially several days before the chicks left the nest and then declined somewhat. We found no differences in rates of growth or blood levels of B, nutrients, and hematocrit as a function of either brood size or parental handicapping. Nestlings within a day of fledging appear to have been food deprived in 1998; their glucose was significantly reduced, and B, free fatty acids, and glycerol were significantly elevated compared to levels in chicks 1-4 d younger. Such changes did not occur in 1999. Blood levels of B were significantly correlated with brood size near the day of fledging, but not earlier, in both years of the study. It was possible to predict the day on which chicks would leave the nest, using their wing length when 12 d old. These results suggest that high blood levels of B associated with food restriction and sibling competition induce chicks to fledge, provided they have reached a critical size, and that the importance of fasting, sibling competition, and B may vary from year to year.

  13. Improvements in PIE-techniques at the IFE hot-laboratory. 'Neutron radiography, three dimensional profilometry and image compilation of PIE data for visualization in an image based user-interface'

    International Nuclear Information System (INIS)

    Jenssen, H.K.; Oberlaender, B.C.

    2002-01-01

    The PIE-techniques used at IFE are continuously improved through upgrading of equipment and methods, e.g. image handling techniques and components utilized in data acquisition and editing techniques. To improve the quality or spatial resolution of neutron radiographs the normal technique was complemented with another method, i.e. the dysprosium foil/X ray film technique is supplemented with a track-etch recorder consisting of a cellulose nitrate film. For further examination of the neutron radiographs the cellulose nitrate film can be digitized to allow electronic image treatment. Promising results were obtained with this technique on neutron radiographs, namely higher spatial resolution compared to the normal technique, high contrast and sharp neutron radiography images. The traditional uniaxial profilometry of fuel rods was modified so that diameter/bow measurements are possible at several angular orientations during one acquisition sequence. This extension is very useful in several ways, for instance the built-in data symmetry of the method is used to check the correctness of the measurement results. Diameter and bow measurements give information of cladding irregularities and fuel rod profiles. Implementation of electronic image handling techniques is particularly useful in PIE when data are collected and compiled in an image file. Inspection and examination of the file contents (examination results) are possible through an ideal user-interface, i.e. Adobe Photoshop software with navigator possibilities. Examples incorporating PIE data acquired from neutron radiography, visual inspection and ceramography are utilized for illustration of the user-interface and some of its possibilities. (author)

  14. Agenesis of the dorsal mesentery presenting in an adolescent

    Directory of Open Access Journals (Sweden)

    Anith Chacko

    2013-03-01

    Full Text Available Agenesis of the dorsal mesentery is a rare occurrence that usually presents in children. It is associated with proximal small bowel malrotation as well as high jejunal atresia with discontinuity of the small bowel. We present a case report of an adolescent presenting with clinical features of proximal small bowel obstruction (confirmed on imaging as well as acute pancreatitis. At laparotomy, he was found to have no dorsal mesentery, without small bowel atresia, and the duodenum was fixed to the posterior abdominal wall. The patient recovered well and remained symptom-free.

  15. Complete dorsal pancreatic agenesis and unilateral renal agenesis.

    Science.gov (United States)

    Moreira, Adriana; Carvalho, André; Portugal, Inês; Jesus, José Miguel

    2018-02-01

    Dorsal pancreatic agenesis is a very rare congenital anomaly. Unilateral renal agenesis, on the other hand, is a relatively common congenital anomaly, although its etiology is not fully understood. Renal and pancreatic embryologic development appears to be nonrelated. We report a case of a 34-year-old man who was referred to our hospital for evaluation of cholestasis and microalbuminuria. Ultrasound and magnetic resonance imaging examinations showed empty right renal fossa and absence of the pancreatic neck, body, and tail. Our case report is the second case of a dorsal pancreatic agenesis and unilateral renal agenesis in a young male patient.

  16. Captive breeding and reintroduction of the oriental pied hornbill (Anthracoceros albirostris) in Khao Kheow Open Zoo, Thailand.

    Science.gov (United States)

    Chaiyarat, Rattanawat; Kongprom, Urarikha; Manathamkamon, Darika; Wanpradab, Sunan; Sangarang, Satean

    2012-01-01

    This article discusses two related issues of the captive breeding and reintroduction of the Oriental pied hornbill (Anthracoceros albirostris) in order to increase its population in the natural habitats. Oriental pied hornbills were bred in Khao Kheow Open Zoo. Three pairs were separated and kept in breeding cages. Females occupied artificial nests between February and April 2005-2007. Eggs were laid and incubated between February and March each year from 2005 to 2007. Nestlings hatched in late March and left the nest in late April 2005-2007. Each breeding pair was fed with approximately 400 g of food each day. All three pairs reproduced resulting in mature offspring of seven in 2005, six in 2006, and five in 2007. Four of sixteen 3-year-old birds were randomly selected and equipped with a GPS receiver on their backs. Activities of the birds attached and unattached with GPS were not significantly different. The first two birds (one female, one male with GPS) were reintroduced on August 5, 2006, and another nine birds (four birds with GPS) were reintroduced on December 26, 2006. The average home range of these reintroduced birds was 0.13 km(2) . Their foods consisted of wild plants and animals in the home range. The first reintroduced pair was able to breed naturally by laying and hatching eggs in an artificial nest. Two juveniles left the nest in April 2008. These results indicate that both captive breeding and reintroduction are potentially important ways to increase the population of the Oriental pied hornbill in natural habitats. © 2011 Wiley Periodicals, Inc.

  17. Aportaciones a la transición del hiero I al hierro II en el centro de la cuenca del udero

    Directory of Open Access Journals (Sweden)

    Manuel GARCÍA ALONSO

    2009-10-01

    Full Text Available En la diversidad de publicaciones que se ponen al alcance del investigador, y que son referidas a la Edad del Hierro, entendida de una manera amplia, se viene observando, en el manejo terminológico más bien, una serie de cuestiones que quedan latentes entre las diferentes tomas de postura; pero que, salvo excepciones, no dan pie a una discusión o puesta en común de las mismas, y que entendemos son de capital importancia para la zona objeto de la presente comunicación.

  18. Comparison of ATF and TJ-II stellarator equilibria as computed by the 3-D VMEC and PIES codes

    International Nuclear Information System (INIS)

    Johnson, J.L.; Monticello, D.A.; Reiman, A.H.; Hirshman, S.P.

    1992-01-01

    A comparison is made of results from the PIES code, which determines the equilibrium properties of three-dimensional toroidal configurations by direct integration along the magnetic field lines, with those from the VMEC code, which uses an energy minimization in a flux representation to determine the equilibrium configuration, for two devices: the ATF stellarator at Oak Ridge and the TJ-11 heliac which is being built in Madrid. The results obtained from the two codes are in good agreement, providing additional validation for the codes

  19. Uso terapêutico da radiofrequência pulsátil no gânglio dorsal da raiz de L2 na lombalgia discogênica Uso terapéutico de la radiofrecuencia pulsátil en el ganglio dorsal de la raíz de L2 en la lumbalgia discogénica Pulsed radiofrequency on L2 dorsal root ganglion as a therapeutic method for lumbar discogenic pain

    Directory of Open Access Journals (Sweden)

    Fabrício Dias Assis

    2009-06-01

    Full Text Available OBJETIVO: Avaliar a eficácia da radiofrequência pulsátil sobre o gânglio da raiz dorsal de L2 no tratamento dos pacientes com lombalgia discogênica. MÉTODOS: Realizou-se análise retrospectiva de 50 pacientes portadores de lombalgia crônica discogênica atendidos no período de janeiro de 2004 a julho de 2007. O processo diagnóstico foi constituído por exame físico, ressonância magnética e bloqueio diagnóstico do gânglio da raiz dorsal de L2. Todos os pacientes foram submetidos à radiofrequência pulsátil no gânglio da raiz dorsal de L2 e acompanhados por, no mínimo, 12 meses. A intensidade de dor foi medida pela escala visual analógica (EVA de dor. RESULTADOS: A análise estatística mostrou melhora significativa da intensidade de dor (pOBJETIVO: evaluar la eficacia de la radiofrecuencia pulsátil sobre el ganglio de la raíz dorsal de L2 en el tratamiento de los pacientes con lumbalgia discogénica. MÉTODOS: fue realizado un análisis retrospectivo de 50 pacientes portadores de lumbalgia crónica discogénica, atendidos en el periodo de Enero de 2004 a Julio de 2007. El proceso diagnóstico constó de un examen físico, resonancia magnética y bloqueo diagnóstico del ganglio de la raíz dorsal de L2. Todos los pacientes fueron sometidos a la radiofrecuencia pulsátil en el ganglio de la raíz dorsal de L2 y seguidos por 12 meses, como mínimo. La intensidad del dolor fue medida por la escala visual analógica del dolor. RESULTADOS: el análisis estadístico mostró mejoría significativa de la intensidad del dolor (pOBJECTIVE: to evaluate the effectiveness of pulsate radio-frequency on L2 dorsal root ganglion for chronic discogenic low back pain. Of L2 in the treatment of the patient with discogenic low back pain. METHODS: Between January 2004 and July 2007, 50 patients with diagnosis of low back discogenic pain were retrospectively assessed based on physical examination, magnetic resonance imaging findings and selective L

  20. Carcass Traits and Meat Quality of Prestice Black-Pied Pig Breed

    Directory of Open Access Journals (Sweden)

    Václav Matoušek

    2016-08-01

    Full Text Available The objective of the study was to evaluate fattening performance, carcass value and meat quality in pigs of Prestice Black-Pied breed in relation to slaughter weight (SW and gender (barrows and gilts, resp.. Pigs were divided into weight categories: SW1 (75 to 99.9 kg, SW2 (100 to 109.9 kg and SW3 (110 to 130 kg and all individual traits were analyzed by the general linear model procedure (SAS 9.3. Average SW of each weight group was as follows: SW1 94.2 kg, SW2 105.8 kg, and SW3 115.2 kg. Differences among average backfat thickness of 36.07 mm in SW1, 40.16 mm in SW2, and 43.21 mm in SW3 were significant (p<0.01. Lean meat content was 48.94% (SW1, 48.78% (SW2, and 48.76% (SW3. Pigs were slaughtered at average weight of 105.7 kg for barrows and 104.4 kg for gilts. Average backfat thickness for barrows was 40.90 mm and 38.72 mm for gilts (significant difference p<0.05. Lean meat content was 48.75% in barrows and 48.91% in gilts. The values of pH45, characterizing the meat of very good quality. The loin in SW3 was darker than the muscles of SW1 and SW2. Drip loss was the lowest in SW1 (1.96%, compared to the highest drip loss in SW3 (2.59%. Content of intramuscular fat was 2.68% in SW3, 2.79% in SW2, and SW1 had the lowest content 2.47%. The values of pH45, colour lightness and drip loss were similar in both genders. However barrows had higher intramuscular fat content by 0.31% than gilts (p<0.05.

  1. THE ACQUISITION OF PREPOSITION STRANDING AND PIED-PIPING BY INDONESIAN STUDENTS LEARNING ENGLISH

    Directory of Open Access Journals (Sweden)

    Drs. Suprapto, M.Hum. Drs. Suprapto, M.Hum.

    2017-04-01

    Full Text Available This article mainly deals with the acquisition of preposition stranding (PS and preposition pied-piping (PPP of English by the students of the English Department of Semarang State University. The main purpose of the study is to reveal their way of mastering this language area which is notably absent in their L1 system (PS. Based on the experience of the writer as a teacher, the different systems of preposition usage between L1 (Indonesian and L2(English constitutes a lot of learning problems. The PS and PPP learning problems encountered by the students are pedagogically appealing in that even the students of higher semester can often plunge into this particular problem (Mi Di 2006. English, and also other Germanic languages, permits both PS and PPP in their sentence constructions while in Indonesian and many other languages in the world the PS constructions do not appear to have a strong grammatical basis (Cable and Harris 2011; Sugisaki 2011. Researchers tried to understand the problem by viewing it through the notion of markedness theory in which language areas which are unmarked are relatively easier to learn than the ones marked. In the issue raised in this paper, the PPP is considered to be unmarked and the PS is more marked (van Buren and Smith 1985; Klein 1993. This study involves 62 students divided into two groups: 30 students of second semester and 32 students of fourth semester. They were given a task to construct sentences with wh-relative clauses using either PPP or PS forms employing different relative pronouns. The result shows that the second semester group tended to use more PPP than PS forms. They also used less PS than the intermediate group did. On the other hand, the fourth semester group tended to use more PS than the elementary did. These findings suggest a significant support towards the effectiveness of markedness theory. The results may also indicate that the theory works most effectively on lower level of learning and

  2. Vortex wake, downwash distribution, aerodynamic performance and wingbeat kinematics in slow-flying pied flycatchers.

    Science.gov (United States)

    Muijres, Florian T; Bowlin, Melissa S; Johansson, L Christoffer; Hedenström, Anders

    2012-02-07

    Many small passerines regularly fly slowly when catching prey, flying in cluttered environments or landing on a perch or nest. While flying slowly, passerines generate most of the flight forces during the downstroke, and have a 'feathered upstroke' during which they make their wing inactive by retracting it close to the body and by spreading the primary wing feathers. How this flight mode relates aerodynamically to the cruising flight and so-called 'normal hovering' as used in hummingbirds is not yet known. Here, we present time-resolved fluid dynamics data in combination with wingbeat kinematics data for three pied flycatchers flying across a range of speeds from near hovering to their calculated minimum power speed. Flycatchers are adapted to low speed flight, which they habitually use when catching insects on the wing. From the wake dynamics data, we constructed average wingbeat wakes and determined the time-resolved flight forces, the time-resolved downwash distributions and the resulting lift-to-drag ratios, span efficiencies and flap efficiencies. During the downstroke, slow-flying flycatchers generate a single-vortex loop wake, which is much more similar to that generated by birds at cruising flight speeds than it is to the double loop vortex wake in hovering hummingbirds. This wake structure results in a relatively high downwash behind the body, which can be explained by the relatively active tail in flycatchers. As a result of this, slow-flying flycatchers have a span efficiency which is similar to that of the birds in cruising flight and which can be assumed to be higher than in hovering hummingbirds. During the upstroke, the wings of slowly flying flycatchers generated no significant forces, but the body-tail configuration added 23 per cent to weight support. This is strikingly similar to the 25 per cent weight support generated by the wing upstroke in hovering hummingbirds. Thus, for slow-flying passerines, the upstroke cannot be regarded as inactive

  3. La estrategia low cost de la marca del distribuidor

    OpenAIRE

    Reynaldo Carrión, Javier

    2013-01-01

    La marca del distribuidor ha experimentado un crecimiento constante desde su creación y en la actualidad ya se ha convertido en un producto habitual en nuestra cesta de la compra. El motivo no es otro que su relación calidad-precio y la diversidad que ofrece actualmente a los consumidores. Esta marca es más conocida a pie de supermercado como marca blanca, aunque cada vez tiene menos de “blanca” y más de “marca”. El cambio de mentalidad de los consumidores y la diversidad de productos que ...

  4. A radiologic study on the urinary bladder following dorsal and ...

    African Journals Online (AJOL)

    Pneumocystography and positive contrast cystography using solutrast® were carried out immediately after surgery and on the second operative day following dorsal and ventral cystotomy in 22 adult mongrel dogs. In all the radiographs, there was no contrast observed in the abdominal cavity and the apex of the bladder had ...

  5. Attention modulates the dorsal striatum response to love stimuli.

    Science.gov (United States)

    Langeslag, Sandra J E; van der Veen, Frederik M; Röder, Christian H

    2014-02-01

    In previous functional magnetic resonance imaging (fMRI) studies concerning romantic love, several brain regions including the caudate and putamen have consistently been found to be more responsive to beloved-related than control stimuli. In those studies, infatuated individuals were typically instructed to passively view the stimuli or to think of the viewed person. In the current study, we examined how the instruction to attend to, or ignore the beloved modulates the response of these brain areas. Infatuated individuals performed an oddball task in which pictures of their beloved and friend served as targets and distractors. The dorsal striatum showed greater activation for the beloved than friend, but only when they were targets. The dorsal striatum actually tended to show less activation for the beloved than the friend when they were distractors. The longer the love and relationship duration, the smaller the response of the dorsal striatum to beloved-distractor stimuli was. We interpret our findings in terms of reinforcement learning. By virtue of using a cognitive task with a full factorial design, we show that the dorsal striatum is not activated by beloved-related information per se, but only by beloved-related information that is attended. Copyright © 2012 Wiley Periodicals, Inc.

  6. Dorsal hand coverage with free serratus fascia flap

    DEFF Research Database (Denmark)

    Fotopoulos, Peter; Holmer, Per; Leicht, Pernille

    2003-01-01

    in the flap, leaving the long thoracic nerve intact on the serratus muscle. Coverage of the flap with split-thickness skin graft is done immediately. The free serratus fascia flap is an ideal flap for dorsal hand coverage when the extensor tendons are exposed, especially because of low donor-site morbidity....

  7. Expression of interleukin-1 beta in rat dorsal root ganglia

    NARCIS (Netherlands)

    Copray, JCVM; Mantingh, [No Value; Brouwer, N; Biber, K; Kust, BM; Liem, RSB; Huitinga, [No Value; Tilders, FJH; Van Dam, AM; Boddeke, HWGM

    2001-01-01

    The expression of interleukin-lp was examined in dorsal root ganglion (DRG) neurons from adult rats using non-radioactive in Situ hybridization and immunocytochemistry. At all spinal levels, approximately 70% of the DRG neurons appeared to express IL-1 beta mRNA: about 80% of these DRG neurons

  8. Slack KNa Channels Influence Dorsal Horn Synapses and Nociceptive Behavior.

    Science.gov (United States)

    Evely, Katherine M; Pryce, Kerri D; Bausch, Anne E; Lukowski, Robert; Ruth, Peter; Haj-Dahmane, Samir; Bhattacharjee, Arin

    2017-01-01

    The sodium-activated potassium channel Slack (Kcnt1, Slo2.2) is highly expressed in dorsal root ganglion neurons where it regulates neuronal firing. Several studies have implicated the Slack channel in pain processing, but the precise mechanism or the levels within the sensory pathway where channels are involved remain unclear. Here, we furthered the behavioral characterization of Slack channel knockout mice and for the first time examined the role of Slack channels in the superficial, pain-processing lamina of the dorsal horn. We performed whole-cell recordings from spinal cord slices to examine the intrinsic and synaptic properties of putative inhibitory and excitatory lamina II interneurons. Slack channel deletion altered intrinsic properties and synaptic drive to favor an overall enhanced excitatory tone. We measured the amplitudes and paired pulse ratio of paired excitatory post-synaptic currents at primary afferent synapses evoked by electrical stimulation of the dorsal root entry zone. We found a substantial decrease in the paired pulse ratio at synapses in Slack deleted neurons compared to wildtype, indicating increased presynaptic release from primary afferents. Corroborating these data, plantar test showed Slack knockout mice have an enhanced nociceptive responsiveness to localized thermal stimuli compared to wildtype mice. Our findings suggest that Slack channels regulate synaptic transmission within the spinal cord dorsal horn and by doing so establishes the threshold for thermal nociception.

  9. Treatment of acute and subacute dorsal perilunate fracture dislocations

    Directory of Open Access Journals (Sweden)

    Levent Kucuk

    2014-04-01

    Outcomes: Results of the perilunate fracture dislocations treated in acute or subacute phase by open reduction and internal fixation via dorsal approach are satisfactory. There is a strong demand for prospective, randomized studies to compare the results of different treatment modalities. [Hand Microsurg 2014; 3(1.000: 1-7

  10. A study of dorsal vein pattern for biometric security

    African Journals Online (AJOL)

    Nafiisah

    ensure more reliable security, many biometric verification techniques have been developed .... 3.0 HA D DORSAL VEI PATTER AS A BIOMETRIC ... image for the back of the hand, and converted by a computer into a digital image that can be.

  11. Dorsal Phalloplasty to Preserve Penis Length after Penile Prosthesis Implantation

    Directory of Open Access Journals (Sweden)

    Osama Shaeer

    2017-03-01

    Full Text Available Objectives: Following penile prosthesis implantation (PPI, patients may complain of a decrease in visible penis length. A dorsal phalloplasty defines the penopubic junction by tacking pubic skin to the pubis, revealing the base of the penis. This study aimed to evaluate the efficacy of a dorsal phalloplasty in increasing the visible penis length following PPI. Methods: An inflatable penile prosthesis was implanted in 13 patients with severe erectile dysfunction (ED at the Kamal Shaeer Hospital, Cairo, Egypt, from January 2013 to May 2014. During the surgery, nonabsorbable tacking sutures were used to pin the pubic skin to the pubis through the same penoscrotal incision. Intraoperative penis length was measured before and after the dorsal phalloplasty. Overall patient satisfaction was measured on a 5-point rating scale and patients were requested to subjectively compare their postoperative penis length with memories of their penis length before the onset of ED. Results: Intraoperatively, the dorsal phalloplasty increased the visible length of the erect penis by an average of 25.6%. The average length before and after tacking was 10.2 ± 2.9 cm and 13.7 ± 2.8 cm, respectively (P <0.002. Postoperatively, seven patients (53.8% reported a longer penis, five patients (38.5% reported no change in length and one patient (7.7% reported a slightly shorter penis. The mean overall patient satisfaction score was 4.9 ± 0.3. None of the patients developed postoperative complications. Conclusion: A dorsal phalloplasty during PPI is an effective method of increasing visible penis length, therefore minimising the impression of a shorter penis after implantation.

  12. Phosphorus sources (P plus filter pie with or without azotofos on the available P in the soil

    Directory of Open Access Journals (Sweden)

    Maikel Abreu Jiménez

    2014-04-01

    Full Text Available The objective of the investigation was to evaluate the effect of four phosphorus sources plus filter pie with or without the biofertilizer Azotofos on the available phosphorus in the soil at different moments after the treatment. An experiment in factorial design 4(2+1 was established, being the four phosphorus sources: rock phosphate, natural phosphate, triple phosphate and Cuban phosphoric rock; two sources of the organic compound to base filter cake enriched with Azotofos microorganisms, only filter cake (without enrichment and a control treatment (without filter pie, neither Azotofos, with three repetitions. The evaluations of the tenor of available P (Bray-2 were carried out at the 30, 60, 90, 120 and 150 days after the installation of the experiment. The tenor of P (Bray-2 was influenced by the sources of P and the enrichment with biofertilizantes (factorial increasing the tenor of available P in front of the control. The triple superphosphate promoted the higher tenors in P in the soil at 60 and 90 days after its application, independently of the presence or not of the organic compound enriched with P solubilizing microorganisms, although this effect didn’t stay stable at the time.

  13. PIE technology on mechanical tests for HTTR core component and structural materials developed at Research Hot Laboratory

    International Nuclear Information System (INIS)

    Kizaki, Minoru; Honda, Junichi; Usami, Kouji; Ouchi, Asao; Oeda, Etsuro; Matsumoto, Seiichiro

    2001-02-01

    The high temperature engineering test reactor (HTTR) with the target operation temperature of 950degC established the first criticality on November, 1998 based on a large amount of R and D results on fuel and materials. In such R and D works, the development of reactor materials are one of the key issues from the view point of reactor environments such as extremely high temperature, neutron irradiation and so on for the HTTR. The Research Hot Laboratory (RHL) had carried out much kind of post irradiation examinations (PIEs) on core component and pressure vessel materials for during more than a quarter century. And obtained data played an important role in development, characterization and licensing of those materials for the HTTR. This paper describes the PIE technology developed at RHL and typical results on mechanical tests such as elevated temperature tensile and creep rupture tests for Hasteloy-X, Incolloy 800H and so on, and Charpy impact, J IC fracture toughness, K Id fracture toughness and small punch tests for normalized and tempered 2 1/4Cr-1Mo steel from historical view. In addition, an electrochemical test technique established for investigating the irradiation embrittlement mechanism on 2 1/4Cr-1Mo steel is also mentioned. (author)

  14. Ulcera cutanea provocada por hongos del genero Fusarium

    Directory of Open Access Journals (Sweden)

    Negroni Ricardo

    1997-01-01

    Full Text Available Se presenta el caso de un paciente oriundo y procedente del Paraguay, de 40 años de edad, portador de una ulceración crónica en cara externa del pie izquierdo, de 2 meses de evolución, debida a una hialohifomicosis por Fusarium oxysporum. Se destacan las características clínicas, métodos de diagnóstico y terapeútica de esta micosis, además de las diferentes etiologías a considerar en el diagnóstico diferencial de una úlcera en personas procedentes del área tropical o subtropical.

  15. Predicting Early Reading Skills from Pre-Reading Measures of Dorsal Stream Functioning

    Science.gov (United States)

    Kevan, Alison; Pammer, Kristen

    2009-01-01

    It is well documented that good reading skills may be dependent upon adequate dorsal stream processing. However, the degree to which dorsal stream deficits play a causal role in reading failure has not been established. This study used coherent motion and visual frequency doubling to examine whether dorsal stream sensitivity measured before the…

  16. Dorsal onlay (Barbagli technique) versus dorsal inlay (Asopa technique) buccal mucosal graft urethroplasty for anterior urethral stricture: a prospective randomized study.

    Science.gov (United States)

    Aldaqadossi, Hussein; El Gamal, Samir; El-Nadey, Mohamed; El Gamal, Osama; Radwan, Mohamed; Gaber, Mohamed

    2014-02-01

    To compare both the dorsal onlay technique of Barbagli and the dorsal inlay technique of Asopa for the management of long anterior urethral stricture. From January 2010 to May 2012, a total of 47 patients with long anterior urethral strictures were randomized into two groups. The first group included 25 patients who were managed by dorsal onlay buccal mucosal graft urethroplasty. The second group included 22 patients who were managed by dorsal inlay buccal mucosal graft urethroplasty. Different clinical parameters, postoperative complications and success rates were compared between both groups. The overall success rate in the dorsal onlay group was 88%, whereas in the dorsal inlay group the success rate was 86.4% during the follow-up period. The mean operative time was significantly longer in the dorsal onlay urethroplasty group (205 ± 19.63 min) than in the dorsal inlay urethroplasty group (128 ± 4.9 min, P-value <0.0001). The average blood loss was significantly higher in the dorsal onlay urethroplasty group (228 ± 5.32 mL) than in the dorsal inlay urethroplasty group (105 ± 12.05 mL, P-value <0.0001). The dorsal onlay technique of Barbagli and the dorsal inlay technique of Asopa buccal mucosal graft urethroplasty provide similar success rates. The Asopa technique is easy to carry out, provides shorter operative time and less blood loss, and it is associated with fewer complications for anterior urethral stricture repair. © 2013 The Japanese Urological Association.

  17. Dorsal approaches to intradural extramedullary tumors of the craniovertebral junction

    Directory of Open Access Journals (Sweden)

    D Refai

    2010-01-01

    Full Text Available Tumors of the craniovertebral junction (CVJ pose significant challenges to cranial and spine surgeons. Familiarity with the complex anatomy and avoidance of injury to neurologic and vascular structures are essential to success. Multiple surgical approaches to address lesions at the CVJ have been promoted, including ventral and dorsal-based trajectories. However, optimal selection of the surgical vector to manage the pathology requires a firm understanding of the limitations and advantages of each approach. The selection of the best surgical trajectory must include several factors, such as obtaining the optimal exposure of the region of interest, avoiding injury to critical neurologic or vascular structures, identification of normal anatomical landmarks, the familiarity and comfort level of the surgeon to the approach, and the need for fixation. This review article focuses on dorsal approaches to the CVJ and the advantages and limitations in managing intradural extramedullary tumors.

  18. Relatos sobre discapacidad y economías de a pie

    OpenAIRE

    Ortells Roca, Miguel Juan; Ortí Porcar, María José; Gimeno Nebot, Cèsar; Grupo de trabajo sobre Discapacidad

    2013-01-01

    ÍNDICE .PRÓLOGO, Miquel Ortells . EL NEGOCIO DEL MATERIAL ORTOPÉDICO, Cèsar Gimeno . HABLAR ELECTRÓNICAMENTE, Sergio Sanahuja . MI CORAZÓN NO RECHAZA EL TRABAJO, Antoni Romero . LAS ADAPTACIONES INFORMÁTICAS PARECEN . PARA ASTRONAUTAS: ¡ESTÁN POR LA ÓRBITA!, Sergio Sanahuja . ALGUIEN ESTÁ HACIENDO NEGOCIOS CON MI DISCAPACIDAD, Santos Cuadros . A CUESTAS CON EL LUJO DE MI DISCAPACIDAD , María Victoria. BENEFICIOS Y GASTOS EXTRA AL COMPRAR...

  19. Rapportering om going concern i den nye revisionspåtegning – særlige forhold for PIE-virksomheder

    DEFF Research Database (Denmark)

    Seehausen, Jesper

    2017-01-01

    Artiklen omhandler særlige forhold for PIE-virksomheder, dvs. virksomheder af interesse for offentligheden, vedrørende going concern. Artikel skal læses i sammenhæng med min generelle artikel vedr. rapportering om going concern i den nye revisionspåtegning, idet denne artikel også er relevant...

  20. Song degradation in the hole-nesting pied flycatcher Ficedula hypoleuca: Implications for polyterritorial behaviour in contrasting habitat-types

    DEFF Research Database (Denmark)

    Lampe, Helene M.; Larsen, Ole Næsbye; Pedersen, Simon Boel

    2007-01-01

    In the hole-nesting pied flycatcher, Ficedula hypoleuca, a male may become polyterritorial after attracting a primary female. However, the female may recognize her mate's song and attack other females that associate with him. Differences in sound degradation amongst different habitats and within ...

  1. Dorsal and ventral changes of the occipital vertebrae

    International Nuclear Information System (INIS)

    Banki, Z.

    1981-01-01

    Based on his own observation and on the literature, the author discusses various types of calcification in the occipital-cervical region, beginning with those situated dorsally and followed by ventral forms. An attempt is made to classify these changes, depending on their morphology and situation, from an embryological point of view. The pro-atlantal and ante pro-atlanto origin of the occipital vertebrae is discussed. Differentiation depends on appearances. (orig.) [de

  2. Bulbar urethroplasty using the dorsal approach: current techniques

    Directory of Open Access Journals (Sweden)

    Barbagli Guido

    2003-01-01

    Full Text Available INTRODUCTION: The use of flaps or grafts is mandatory in patients with longer and complex strictures. In 1995-96 we described a new dorsal onlay graft urethroplasty. Over time, our original technique was better defined and changed. Now this procedure (also named Barbagli technique has been greeted with a fair amount of enthusiasm in Europe and in the United States. SURGICAL TECHNIQUE: The patient is placed in normal lithotomy position, and a midline perineo-scrotal incision is made. The bulbar urethra is then free from the bulbo-cavernous muscles, and is dissected from the corpora cavernosa. The urethra is completely mobilized from the corpora cavernosa, it is rotated 180 degrees, and is incised along its dorsal surface. The graft (preputial skin or buccal mucosa or the flap is fixed and quilted to the tunica albuginea of the corporal bodies. The right mucosal margin of the opened urethra is sutured to the right side of the patch-graft. The urethra is rotated back into its original position. The left urethral margin is sutured to the left side of the patch graft and to the corporal bodies, and the grafted area is entirely covered by the urethral plate. The bulbo-cavernous muscles are approximated over the grafted area. A 16F silicone Foley catheter is left in place. COMMENTS: Dorsal onlay graft urethroplasty is a versatile procedure that may be combined with various substitute materials like preputial skin, buccal mucosa grafts or pedicled flaps.

  3. Diagnosis of dorsal inter osseous pseudotumours by magnetic resonance imaging

    International Nuclear Information System (INIS)

    Peh, W.C.G.; Wong, L.L.S.; Ip, W.Y.

    1999-01-01

    Two middle-aged-patients each presenting with a progressively enlarging mass in the first dorsal web space of their hands are reported. Magnetic resonance imaging (MRI) demonstrated the cause to be a hypertrophic first dorsal inter osseous muscle, with normal T1, T2 and post-gadopentetate dimeglumine signal characteristics. The ability of MRI to diagnose anatomical variants of hand muscles is important in the clinical management of patients with these pseudotumours. The usefulness of magnetic resonance imaging (MRI) in evaluation of soft tissue tumours of the musculoskeletal system is now widely accepted. Its ability to maximize contrast between tumour and adjacent normal tissue in a multiplanar manner makes it the imaging modality of choice in pre-operative staging of soft tissue masses. In the hand and wrist, where benign tumours predominate, MRI may provide a specific diagnosis. We describe two cases in which MRI demonstrated the cause of a hand pseudotumour to be due to hypertrophy of the first dorsal inter osseous muscle. Copyright (1999) Blackwell Science Pty Ltd

  4. Diagnosis of dorsal inter osseous pseudotumours by magnetic resonance imaging

    Energy Technology Data Exchange (ETDEWEB)

    Peh, W.C.G.; Wong, L.L.S. [The University of Hong Kong, Queen Mary Hospital, (Hong Kong). Hand Surgery Division, Department of Diagnotic Radiology; Ip, W.Y. [The University of Hong Kong, Queen Mary Hospital, (Hong Kong). Hand Surgery Division, Department of Orthopaedic Surgery

    1999-08-01

    Two middle-aged-patients each presenting with a progressively enlarging mass in the first dorsal web space of their hands are reported. Magnetic resonance imaging (MRI) demonstrated the cause to be a hypertrophic first dorsal inter osseous muscle, with normal T1, T2 and post-gadopentetate dimeglumine signal characteristics. The ability of MRI to diagnose anatomical variants of hand muscles is important in the clinical management of patients with these pseudotumours. The usefulness of magnetic resonance imaging (MRI) in evaluation of soft tissue tumours of the musculoskeletal system is now widely accepted. Its ability to maximize contrast between tumour and adjacent normal tissue in a multiplanar manner makes it the imaging modality of choice in pre-operative staging of soft tissue masses. In the hand and wrist, where benign tumours predominate, MRI may provide a specific diagnosis. We describe two cases in which MRI demonstrated the cause of a hand pseudotumour to be due to hypertrophy of the first dorsal inter osseous muscle. Copyright (1999) Blackwell Science Pty Ltd 20 refs., 3 figs.

  5. Compound dorsal dislocation of lunate with trapezoid fracture

    Directory of Open Access Journals (Sweden)

    Bong-Sung Kim

    2016-12-01

    Full Text Available We report about a dorsal dislocation of the lunate accompanied by a trapezoid fracture in a 41-year old male patient after a motorcycle accident. The lunate dislocation with no dorsal or volar intercalated segment instability (DISI, VISI was diagnosed by x-ray whereas the trapezoid fracture was only diagnosable by computed tomography. A closed reduction and internal fixation of the lunate by two Kirschner wires was performed, the trapezoid fracture was conservatively treated. Surgery was followed by immobilization, intense physiotherapy and close follow-up. Even though complaints such as swelling and pain subsided during the course of rehabilitation, partial loss of strength and range of motion remained even after 16 months. In conclusion, a conservative treatment of trapezoid fractures seems to be sufficient in most cases. Closed reduction with Kwire fixation led to an overall satisfactory result in our case. For dorsal lunate dislocations in general, open reduction should be performed when close reduction is unsuccessful or DISI/VISI are observed in radiographs after attempted close reduction.

  6. Alzheimer disease: functional abnormalities in the dorsal visual pathway.

    LENUS (Irish Health Repository)

    Bokde, Arun L W

    2012-02-01

    PURPOSE: To evaluate whether patients with Alzheimer disease (AD) have altered activation compared with age-matched healthy control (HC) subjects during a task that typically recruits the dorsal visual pathway. MATERIALS AND METHODS: The study was performed in accordance with the Declaration of Helsinki, with institutional ethics committee approval, and all subjects provided written informed consent. Two tasks were performed to investigate neural function: face matching and location matching. Twelve patients with mild AD and 14 age-matched HC subjects were included. Brain activation was measured by using functional magnetic resonance imaging. Group statistical analyses were based on a mixed-effects model corrected for multiple comparisons. RESULTS: Task performance was not statistically different between the two groups, and within groups there were no differences in task performance. In the HC group, the visual perception tasks selectively activated the visual pathways. Conversely in the AD group, there was no selective activation during performance of these same tasks. Along the dorsal visual pathway, the AD group recruited additional regions, primarily in the parietal and frontal lobes, for the location-matching task. There were no differences in activation between groups during the face-matching task. CONCLUSION: The increased activation in the AD group may represent a compensatory mechanism for decreased processing effectiveness in early visual areas of patients with AD. The findings support the idea that the dorsal visual pathway is more susceptible to putative AD-related neuropathologic changes than is the ventral visual pathway.

  7. Dorsal onlay vaginal graft urethroplasty for female urethral stricture

    Directory of Open Access Journals (Sweden)

    Manmeet Singh

    2013-01-01

    Full Text Available Introduction: Female urethral stricture is an underdiagnosed and overlooked cause of female bladder outlet obstruction. The possible etiologies may be infection, prior dilation, difficult catheterization with subsequent fibrosis, urethral surgery, trauma, or idiopathic. We present our technique and results of dorsal onlay full thickness vaginal graft urethroplasty for female urethral stricture. Materials and Methods: A retrospective review was performed on 16 female patients with mid-urethral stricture who underwent dorsal onlay vaginal graft urethroplasty from January 2007 to June 2011.Of these, 13 patients had previously undergone multiple Hegar dilatations, three had previous internal urethrotomies. The preoperative work up included detailed voiding history, local examination, uroflowmetry, calibration, and micturating cystourethrogram. Results: All patients had mid-urethral stricture. Mean age was 47.5 years. Mean Q max improved from 6.2 to 27.6 ml/s. Mean residual volume decreased from 160 to 20 ml. Mean duration of follow-up was 24.5 months (6 months to 3 years. Only one patient required self-calibration for 6 months after which her stricture stabilized. None of the patient was incontinent. Conclusion: Dorsal vaginal onlay graft urethroplasty could be considered as an effective way to treat female urethral stricture.

  8. Harmane inhibits serotonergic dorsal raphe neurons in the rat.

    Science.gov (United States)

    Touiki, Khalid; Rat, Pascal; Molimard, Robert; Chait, Abderrahman; de Beaurepaire, Renaud

    2005-11-01

    Harmane and norharmane (two beta-carbolines) are tobacco components or products. The effects of harmane and norharmane on serotonergic raphe neurons remain unknown. Harmane and norharmane are inhibitors of the monoamine oxidases A (MAO-A) and B (MAO-B), respectively. To study the effects of harmane, norharmane, befloxatone (MAOI-A), and selegiline (MAOI-B) on the firing of serotonergic neurons. To compare the effects of these compounds to those of nicotine (whose inhibitory action on serotonergic neurons has been previously described). The effects of cotinine, a metabolite of nicotine known to interact with serotonergic systems, are also tested. In vivo electrophysiological recordings of serotonergic dorsal raphe neurons in the anaesthetized rat. Nicotine, harmane, and befloxatone inhibited serotonergic dorsal raphe neurons. The other compounds had no effects. The inhibitory effect of harmane (rapid and long-lasting inhibition) differed from that of nicotine (short and rapidly reversed inhibition) and from that of befloxatone (slow, progressive, and long-lasting inhibition). The inhibitory effects of harmane and befloxatone were reversed by the 5-HT1A antagonist WAY 100 635. Pretreatment of animals with p-chlorophenylalanine abolished the inhibitory effect of befloxatone, but not that of harmane. Nicotine, harmane, and befloxatone inhibit the activity of raphe serotonergic neurons. Therefore, at least two tobacco compounds, nicotine and harmane, inhibit the activity of serotonergic neurons. The mechanism by which harmane inhibits serotonergic dorsal raphe neurons is likely unrelated to a MAO-A inhibitory effect.

  9. Subpoblaciones neuronales presentes en el ganglio de la raíz dorsal

    Directory of Open Access Journals (Sweden)

    Marlén Martínez

    2000-09-01

    Full Text Available La función principal de las neuronas del ganglio de la raiz dorsal (GRD es transmitir la información sensorial desde la periferia hasta el sistema nervioso central. Dos clases de células están presentes en el ganglio: las células no neuronales y las neuronales. La heterogeneidad morfológica, fisiológica y bioquimica de la población neuronal permite diferenciarla en subpoblaciones. Morfológicarnente, se distinguen tres tipos neuronales (A, B y C segun el tamaño y las caracteristicas ultraestructurales. Fisiológicamente, hay una relación directa entre el tamaño, el diámetro de las fibras nerviosas y la velocidad con que conducen el impulso nervioso. Finalmente, el uso de marcadores (neuropéptidos, enzimas, receptores, etc. permite realizar una clasificación bioquímica, que es la más utilizada para estudiar la función neuronal. Este articulo revisa la evidencia experimental sobre el tema de la heterogeneidad neuronal del GRD v wresenta una correlación desde el punto de vista bioauimico v fisioló-o ico en los casos en dondé'hay información disponible. El esiudio de subpoblaciones en este ganglio resulta de bastante interés para investigaciones en neurociencias, principalmente en infecciones por virus neurotrópicos, traurnatismos del nervio periférico y el estudio de factores neurotróficos, entre otros.

  10. Does a rival’s song elicit territorial defense in a tropical songbird, the Pied Bush Chat (Saxicola caprata?

    Directory of Open Access Journals (Sweden)

    Navjeevan Dadwal

    2017-05-01

    Full Text Available The purpose of bird song and the way in which it is delivered has been argued to be adapted mainly for territorial defense. We performed a field experiment with the combination of playbacks and a model to test how much song actually relates to increased territorial defense in the territorial tropical songbird, the Pied Bush Chat, during breeding season (Feb–May, 2015 at Haridwar, Himalayan Foothills, India. As expected, the results of the experiment indicated that song was the major cue used by territory holders to cope with rival intrusions. The song rate was particularly escalated during simulated territorial interactions when the model was presented with a playback song of conspecifics. Behaviors such as restlessness (perch change, the height of perch, and distance from the model appeared to be of relatively lesser importance. To our knowledge, no avian species from the Indian subcontinent has been studied to provide evidence that song can escalate aggressive response by a territory owner.

  11. Emission computer tomography on a Dodewaard mixed oxide fuel pin. Comparative PIE work with non-destructive and destructive techniques

    Energy Technology Data Exchange (ETDEWEB)

    Buurveld, H.A.; Dassel, G.

    1993-12-01

    A nondestructive technique as well as a destructive PIE technique have been used to verify the results obtained with a newly 8-e computer tomography (GECT) system. Multi isotope Scanning (MIS), electron probe micro analysis (EPMA) and GECT were used on a mixed oxide (MOX) fuel rod from the Dodewaard reactor with an average burnup of 24 MWd/kg fuel. GECT shows migration of Cs to the periphery of fuel pellets and to radial cracks and pores in the fuel, whereas MIS shows Cs migration to pellet interfaces. The EPMA technique appeared not to be useful to show migration of Cs but, it shows the distribution of fission products from Pu. EPMA clearly shows the distribution of fission products from Pu, but did not reveal the Cs-migration. (orig./HP)

  12. Peces del Noroeste del Ecuador

    OpenAIRE

    Barriga, Ramiro

    1994-01-01

    La ictiofauna del occidente del Ecuador es poco conocida. Los peces del noroccidente son diferentes a los del suroccidente del Ecuador. 34 familias y 82 especies fueron colectadas que equivale al 11 % de las especies de peces continentales registradas en el Ecuador. Icteogeográficamente se sabe que la costa ecuatoriana posee dos provincias: la del Pacifico Norte y la del Guayas, se determinó que el límite de las dos provincias es el río Santiago ya que las especies del mencionado río so...

  13. Análisis de la estabilidad del cerro Shishio mediante el empleo de técnicas numéricas

    OpenAIRE

    Vintimilla Avila, Maribel Cristina

    2011-01-01

    La presente investigación analiza la estabilidad existente en el Cerro Shishio ubicado en el sector de La Josefina por medio de técnicas numéricas. El deslizamiento del cerro Shishio provocado por el desfogue de las aguas represadas por el deslizamiento del cerro Tamuga, se originó en el material de la Formación Tarqui, el mismo que se deslizó sobre un roca intrusiva muy alterada. En la actualidad se puede observar el material deslizado acumulado al pie del talud, que ahora sirve de soporte ...

  14. Lepra histioide con lesiones gigantes de los dedos de manos y pies

    Directory of Open Access Journals (Sweden)

    Gerzaín Rodríguez

    2015-06-01

    La paciente recibió quimioterapia antileprosa (Organización Mundial de la Salud con resultados excelentes. Se concluyó que un infiltrado dérmico difuso con histiocitos fusiformes y algunos vacuolados, que sugiere un tumor fusocelular, cuya inmunohistoquímica sea particularmente rica en células positivas para CD68, debe teñirse con Ziehl-Neelsen, lo que revelará abundantes bacilos si la lesión es de lepra. La adecuada correlación clínico-patológica es necesaria para establecer el diagnóstico y el manejo preciso del paciente.

  15. Pie varus equino congénito (Factores etiológicos

    Directory of Open Access Journals (Sweden)

    Valentín Malagón-Castro

    1955-04-01

    Full Text Available La causa eficiente del pié varus equino congénito, es en la actualidad desconocida. Existen, sin embargo, múltiples teorías orientadas a la explicación de este problema : Teorías atávica y arquiterígea, de Bardeleben, 1878 y Gegenbauer, 1864. Teoría de la Falla circulatoria de Keith, 1940, y de la Displasia fetal de Streeter, 1930; Teoría de la "Flictena" de Bagg, 1920 y Bonnevie, 1934. La Miodistrofia de Middleton, 1934; La presión mecánica intrauterina de Hipócrates, Dermis Browne, etc. La acción de las bridas amniótica y de la Enfermedad ulcerosa del amnios. Ombredanne. La detención en el desarrollo embrionario. Bohm. Los factores genéticos y las causas adyuvantes que pueden obrar sobre éstos: Deficiencia de la dieta materna durante el embarazo; irradiaciones, traumas, enfermedades y drogas recibidas durante la gestación, etc.

  16. Rare patterns of dorsal puncture in Pterostichus oblongopunctatus (Coleoptera: Carabidae

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    Axel Schwerk

    2018-04-01

    Full Text Available Background The carabid beetle species Pterostichus oblongopunctatus is common in different types of forests in Poland and Europe. With respect to this species, some unclarities exist concerning the morphological feature of punctures on the elytra. P. oblongopunctatus has dorsal pits in the third interval of the elytra, the available identification keys, however, provide inconsistent information concerning the puncture in other intervals. During long-term studies at different study sites in Poland, the first author rarely but regularly discovered individuals with unusual dorsal puncture patterns, i.e., pits in the fifth and even in the seventh interval of the elytra. Since such rare patterns might be connected with special habitat characteristics, and thus have a potential as an indicator, the aim of the study was to test if they are connected with specific subpopulations (interaction groups, if they are related to the sex or size of the beetles, and if they are related to specific habitat conditions. Material and Methods We counted the pits on the elytra, determined the sex, and measured the length of the right elytron of individuals of P. oblongopunctatus collected at numerous study sites located within the borders of the Regional Directory of National Forests in Piła (Western Poland over the period 2014–2016. Results Altogether, 1,058 individuals of P. oblongopunctatus were subjected to statistical analysis. Almost 19% of the individuals had a dorsal puncture in the fifth interval of the elytra and about 0.7% had a dorsal puncture in the seventh interval of the elytra. In 2014 and 2015, significantly more females exhibited such unusual patterns of dorsal puncture than males. Even if not statistically significant, in 2016 also relatively more females showed such a pattern. Neither males nor females of the analysed individuals with usual puncture patterns showed a significant difference in the length of the right elytron from those with

  17. Automatic phoneme category selectivity in the dorsal auditory stream.

    Science.gov (United States)

    Chevillet, Mark A; Jiang, Xiong; Rauschecker, Josef P; Riesenhuber, Maximilian

    2013-03-20

    Debates about motor theories of speech perception have recently been reignited by a burst of reports implicating premotor cortex (PMC) in speech perception. Often, however, these debates conflate perceptual and decision processes. Evidence that PMC activity correlates with task difficulty and subject performance suggests that PMC might be recruited, in certain cases, to facilitate category judgments about speech sounds (rather than speech perception, which involves decoding of sounds). However, it remains unclear whether PMC does, indeed, exhibit neural selectivity that is relevant for speech decisions. Further, it is unknown whether PMC activity in such cases reflects input via the dorsal or ventral auditory pathway, and whether PMC processing of speech is automatic or task-dependent. In a novel modified categorization paradigm, we presented human subjects with paired speech sounds from a phonetic continuum but diverted their attention from phoneme category using a challenging dichotic listening task. Using fMRI rapid adaptation to probe neural selectivity, we observed acoustic-phonetic selectivity in left anterior and left posterior auditory cortical regions. Conversely, we observed phoneme-category selectivity in left PMC that correlated with explicit phoneme-categorization performance measured after scanning, suggesting that PMC recruitment can account for performance on phoneme-categorization tasks. Structural equation modeling revealed connectivity from posterior, but not anterior, auditory cortex to PMC, suggesting a dorsal route for auditory input to PMC. Our results provide evidence for an account of speech processing in which the dorsal stream mediates automatic sensorimotor integration of speech and may be recruited to support speech decision tasks.

  18. Shape representations in the primate dorsal visual stream

    Directory of Open Access Journals (Sweden)

    Tom eTheys

    2015-04-01

    Full Text Available The primate visual system extracts object shape information for object recognition in the ventral visual stream. Recent research has demonstrated that object shape is also processed in the dorsal visual stream, which is specialized for spatial vision and the planning of actions. A number of studies have investigated the coding of 2D shape in the anterior intraparietal area (AIP, one of the end-stage areas of the dorsal stream which has been implicated in the extraction of affordances for the purpose of grasping. These findings challenge the current understanding of area AIP as a critical stage in the dorsal stream for the extraction of object affordances. The representation of three-dimensional (3D shape has been studied in two interconnected areas known to be critical for object grasping: area AIP and area F5a in the ventral premotor cortex (PMv, to which AIP projects. In both areas neurons respond selectively to 3D shape defined by binocular disparity, but the latency of the neural selectivity is approximately 10 ms longer in F5a compared to AIP, consistent with its higher position in the hierarchy of cortical areas. Furthermore F5a neurons were more sensitive to small amplitudes of 3D curvature and could detect subtle differences in 3D structure more reliably than AIP neurons. In both areas, 3D-shape selective neurons were co-localized with neurons showing motor-related activity during object grasping in the dark, indicating a close convergence of visual and motor information on the same clusters of neurons.

  19. Fat opacities dorsal to the equine antebrachiocarpal joint

    International Nuclear Information System (INIS)

    Dietze, A.E.; Rendano, V.T.

    1984-01-01

    Radiolucencies due to fat in the soft tissues dorsal to the equine antebrachiocarpal joint were studied in 12 necropsy specimens. In lateral-to-medial xeroradiographs of these 12 specimens, focal radiolucencies were present in ten, one focal radiolucency was present in one, and no focal radiolucencies were present in ten, one focal radiolucency was present in one, and no focal radiolucencies were in another. These radiolucencies were identified as fat in the antebrachiocarpal joint capsule. The fat was in two locations within this joint capsule. It was associated with the synovial membrane of the extensor carpi radialis tendon sheath and the synovial membrane of the antebrachiocarpal joint

  20. Covering the Dorsal Finger Defect with Reverse Cross Finger Flap

    Directory of Open Access Journals (Sweden)

    Kaan Gurbuz

    2014-12-01

    Full Text Available Reconstruction of finger extensor zone defects with or without tendon gaps still remains a challenge for surgeons. Although surgical treatments may differ, and range from the use of local, regional, to free flaps, the outcomes for all cases are not satisfactory. In this case report, we present a case of a 3rd finger extensor side crush injury including a defect of Dd (Digit Dorsal 1, Dd2 and Dd3 defects of extensor zones with tendon gap. Tendon gap was reconstructed using m. palmaris longus tendon graft and the defect was covered with reversed cross-finger flap (random pattern with good cosmetic and excellent functional results.

  1. Posture And Dorsal Shape At A Sitted Workstation

    Science.gov (United States)

    Lepoutre, F. X.; Cloup, P.; Guerra, T. M.

    1986-07-01

    The ergonomic analysis of a control or a supervision workstation for a vehicle or a process, necessitates to take into account the biomecanical visuo-postural system. The measurements, which are necessary to do, must give informations about the spatial direction of the limbs, the dorsal shape, eventually the eyes direction, and the postural evolution during the working time. More, the smallness of the work station, the backrest and sometime a vibratory environment made use specific, strong and small devices wich do not disturb the operator. The measurement system which we propose is made of an optical device. This system is studied in relation with the french "Institute de Recherche pour les Transports" for an ergonomic analysis of a truck cabin. The optical device consists on placing on the body of the driver on particular places materializing specially members and trunck joint points, some drops which reflect the infra-red raies coming from a specific light. Several cameras whose relative positions depend on the experiment site, transmit video signals to the associated treatment systems which extract the coordinates (Xi, Yi) of each drop in the observation scope of any camera. By regrouping the informations obtained from every view, it is possible to obtain the spatial drop position and then to restore the individual's posture in three dimensions. Therefore, this device doesn't enable us, in consideration of the backrest, to analyse the dorsal posture, which is important with regard to dorsal pains frequency. For that reason, we complete the measurements by using a "curvometer". This device consists of a flexible stick fixed upon the individual back with elastic belts, whose distorsions (curvature in m-1) are measured, in the individual's sagittal plane, with 4 strain gauges pairs; located approximately at the level of vertebra D1, D6, D10 and L3. A fifth measurement, concerning the inclination (in degree) of the lower part of the stick, makes it is possible to

  2. Corrections to the 148Nd method of evaluation of burnup for the PIE samples from Mihama-3 and Genkai-1 reactors

    International Nuclear Information System (INIS)

    Suyama, Kenya; Mochizuki, Hiroki

    2006-01-01

    The value of the burnup is one of the most important parameters of samples taken by post-irradiation examination (PIE). Generally, it is evaluated by the Neodymium-148 method. Precise evaluation of the burnup value requires: (1) an effective fission yield of 148 Nd; (2) neutron capture reactions of 147 Nd and 148 Nd; (3) a conversion factor from fissions per initial heavy metal to the burnup unit GWd/t. In this study, the burnup values of the PIE data from Mihama-3 and Genkai-1 PWRs, which were taken by the Japan Atomic Energy Research Institute, were re-evaluated using more accurate corrections for each of these three items. The PIE data were then re-analyzed using SWAT and SWAT2 code systems with JENDL-3.3 library. The re-evaluation of the effective fission yield of 148 Nd has an effect of 1.5-2.0% on burnup values. Considering the neutron capture reactions of 147 Nd and 148 Nd removes dependence of C/E values of 148 Nd on the burnup value. The conversion factor from FIMA(%) to GWd/t changes according to the burnup value. Its effect on the burnup evaluation is small for samples having burnup of larger than 30 GWd/t. The analyses using the corrected burnup values showed that the calculated 148 Nd concentrations and the PIE data is approximately 1%, whereas this was 3-5% in prior analyses. This analysis indicates that the burnup values of samples from Mihama-3 and Genkai-1 PWRs should be corrected by 2-3%. The effect of re-evaluation of the burnup value on the neutron multiplication factor is an approximately 0.6% change in PIE samples having the burnup of larger than 30 GWd/t. Finally, comparison between calculation results using a single pin-cell model and an assembly model is carried out. Because the results agreed with each other within a few percent, we concluded that the single pin-cell model is suitable for the analysis of PIE samples and that the underestimation of plutonium isotopes, which occurred in the previous analyses, does not result from a geometry

  3. Corrections to the {sup 148}Nd method of evaluation of burnup for the PIE samples from Mihama-3 and Genkai-1 reactors

    Energy Technology Data Exchange (ETDEWEB)

    Suyama, Kenya [Fuel Cycle Facility Safety Research Group, Nuclear Safety Research Center, Japan Atomic Energy Agency, Tokai-mura, Naka-gun, Ibaraki 319-1195 (Japan)]. E-mail: suyama.kenya@jaea.go.jp; Mochizuki, Hiroki [Japan Research Institute, Limited, 16 Ichiban-cho, Chiyoda-ku, Tokyo 102-0082 (Japan)

    2006-03-15

    The value of the burnup is one of the most important parameters of samples taken by post-irradiation examination (PIE). Generally, it is evaluated by the Neodymium-148 method. Precise evaluation of the burnup value requires: (1) an effective fission yield of {sup 148}Nd; (2) neutron capture reactions of {sup 147}Nd and {sup 148}Nd; (3) a conversion factor from fissions per initial heavy metal to the burnup unit GWd/t. In this study, the burnup values of the PIE data from Mihama-3 and Genkai-1 PWRs, which were taken by the Japan Atomic Energy Research Institute, were re-evaluated using more accurate corrections for each of these three items. The PIE data were then re-analyzed using SWAT and SWAT2 code systems with JENDL-3.3 library. The re-evaluation of the effective fission yield of {sup 148}Nd has an effect of 1.5-2.0% on burnup values. Considering the neutron capture reactions of {sup 147}Nd and {sup 148}Nd removes dependence of C/E values of {sup 148}Nd on the burnup value. The conversion factor from FIMA(%) to GWd/t changes according to the burnup value. Its effect on the burnup evaluation is small for samples having burnup of larger than 30 GWd/t. The analyses using the corrected burnup values showed that the calculated {sup 148}Nd concentrations and the PIE data is approximately 1%, whereas this was 3-5% in prior analyses. This analysis indicates that the burnup values of samples from Mihama-3 and Genkai-1 PWRs should be corrected by 2-3%. The effect of re-evaluation of the burnup value on the neutron multiplication factor is an approximately 0.6% change in PIE samples having the burnup of larger than 30 GWd/t. Finally, comparison between calculation results using a single pin-cell model and an assembly model is carried out. Because the results agreed with each other within a few percent, we concluded that the single pin-cell model is suitable for the analysis of PIE samples and that the underestimation of plutonium isotopes, which occurred in the previous

  4. Arco del milenio

    Directory of Open Access Journals (Sweden)

    Adell, Josep Mª

    2005-02-01

    the most significant stages in the erection of the Millennium Arch outside the Palacio de Congresos, venue for the 12th IBMAC.
    These pictures are divided into six chapters: Background, Components, Springline, Piers, Arch, Centring Erection and Removal, and Trimming.

    A lo largo de la historia, el Arco de fábrica ha sido el componente constructivo más característico de la Arquitectura y la Ingeniería desde que después de sus inicios etruscos en la época romana fuera desarrollado adelantándose con ello a la cultura helénica.
    El Arco, desde entonces, viene empleándose como una solución constructiva eficiente para cubrir espacios con materiales que no soportan tracciones. La originalidad técnica del Arco lo ha llevado a imponerse como símbolo de las hazañas bélicas como era el Arco de Triunfo.
    En el cambio de siglo y milenio en el que nos encontramos, un salto técnico fundamental se desvela en este Congreso, el Sistema de Albañilería Integral, que abre la posibilidad de ampliar el campo de aplicación de la albañilería con la incorporación del acero, a través de las perforaciones de las piezas, lográndose por fin armar en las tres direcciones del espacio cualquier muro de fábrica que se desee.
    El Arco del Milenio conmemoró el 12th IBMAC de Madrid, mostrando en él los avances técnicos que el Sistema de Albañilería Integral permite, al tratarse de un arco inclinado en el espacio y, por tanto, el primer arco de fábrica construido fuera de la vertical, mediante fábrica de Ladriflor aparejada a tizón, reforzada con barras y cercos.
    El Arco del Milenio, diseñado por J.M. Adell (Presidente del 12th IBMAC, parte de un cilindro de 14 m de diámetro, inclinado 30º sobre el terreno, y construido con fábrica de ladrillo de un pie de grueso, alternando una hilada de color amarillo de cada seis en rojo. El hueco deja un paso libre de 10 m de lado y 5,5 m de altura. La fábrica está armada regularmente por tendeles con cerchas cada

  5. Hydrodynamic function of dorsal fins in spiny dogfish and bamboo sharks during steady swimming.

    Science.gov (United States)

    Maia, Anabela; Lauder, George V; Wilga, Cheryl D

    2017-11-01

    A key feature of fish functional design is the presence of multiple fins that allow thrust vectoring and redirection of fluid momentum to contribute to both steady swimming and maneuvering. A number of previous studies have analyzed the function of dorsal fins in teleost fishes in this context, but the hydrodynamic function of dorsal fins in freely swimming sharks has not been analyzed, despite the potential for differential functional roles between the anterior and posterior dorsal fins. Previous anatomical research has suggested a primarily stabilizing role for shark dorsal fins. We evaluated the generality of this hypothesis by using time-resolved particle image velocimetry to record water flow patterns in the wake of both the anterior and posterior dorsal fins in two species of freely swimming sharks: bamboo sharks ( Chiloscyllium plagiosum ) and spiny dogfish ( Squalus acanthias ). Cross-correlation analysis of consecutive images was used to calculate stroke-averaged mean longitudinal and lateral velocity components, and vorticity. In spiny dogfish, we observed a velocity deficit in the wake of the first dorsal fin and flow acceleration behind the second dorsal fin, indicating that the first dorsal fin experiences net drag while the second dorsal fin can aid in propulsion. In contrast, the wake of both dorsal fins in bamboo sharks displayed increased net flow velocity in the majority of trials, reflecting a thrust contribution to steady swimming. In bamboo sharks, fluid flow in the wake of the second dorsal fin had higher absolute average velocity than that for first dorsal fin, and this may result from a positive vortex interaction between the first and second dorsal fins. These data suggest that the first dorsal fin in spiny dogfish has primarily a stabilizing function, while the second dorsal fin has a propulsive function. In bamboo sharks, both dorsal fins can contribute thrust and should be considered as propulsive adjuncts to the body during steady

  6. Barrera del desempeño laboral

    Directory of Open Access Journals (Sweden)

    María Del Rosario Alvarez-Ramirez

    2007-12-01

    Full Text Available El estres es un hecho complejo en la vida de toda persona con efectos distintos en cada quien, que no puede ser evitada ya que en todos lo momentos de la vida se esta en riesgo de presentarlo ante cualquier situacion, o una actividad laboral o familiar, que puede llegar a generar cualquier cambio que represente estres. Los sucesos negativos, dario, enfermedad o muerte de un ser querido, son hechos estresantes, asi como los sucesos positivos; ascender en el trabajo trae consigo el estres del nuevo status, de nuevas responsabilidades. Dentro de los trastornos clinicos vinculados al estres hay alteraciones como: trastornos del sumo, ulceras, dolores de cabeza, aceleracion del ritmo cardiaco y otros trastornos como los cardiovasculares: palpitaciones, hipertension arterial, trastornos digestivos, dolores, ardores, vomitos, nauseas, diarrea o estreriimiento y trastornos cutaneos: donde se presenta transpiracion de manos y pies y problemas alergicos. En el estres se pueden llegar a presentar dos tipos de estres: el positivo y el negativo. Los cuales presentan unas caracteristicas muy particulares, como en el estres negativo: una persona se encuentra ante un nitmero creciente de demandas que le plantean dificultad o constituyen una amenaza, se debe mirar el modo de afrontarlas. En el Estres positivo se presenta cuando la percepcion de capacidad de demanda es mucho mas amplia que las verdaderas demandas. Un aspecto fundamental ante la presencia de estres es la practica necesaria de un deporte o la realizacion de actividades recreativas.

  7. Synaptically evoked glutamate transporter currents in Spinal Dorsal Horn Astrocytes

    Directory of Open Access Journals (Sweden)

    Dougherty Patrick M

    2009-07-01

    Full Text Available Abstract Background Removing and sequestering synaptically released glutamate from the extracellular space is carried out by specific plasma membrane transporters that are primarily located in astrocytes. Glial glutamate transporter function can be monitored by recording the currents that are produced by co-transportation of Na+ ions with the uptake of glutamate. The goal of this study was to characterize glutamate transporter function in astrocytes of the spinal cord dorsal horn in real time by recording synaptically evoked glutamate transporter currents. Results Whole-cell patch clamp recordings were obtained from astrocytes in the spinal substantia gelatinosa (SG area in spinal slices of young adult rats. Glutamate transporter currents were evoked in these cells by electrical stimulation at the spinal dorsal root entry zone in the presence of bicuculline, strychnine, DNQX and D-AP5. Transporter currents were abolished when synaptic transmission was blocked by TTX or Cd2+. Pharmacological studies identified two subtypes of glutamate transporters in spinal astrocytes, GLAST and GLT-1. Glutamate transporter currents were graded with stimulus intensity, reaching peak responses at 4 to 5 times activation threshold, but were reduced following low-frequency (0.1 – 1 Hz repetitive stimulation. Conclusion These results suggest that glutamate transporters of spinal astrocytes could be activated by synaptic activation, and recording glutamate transporter currents may provide a means of examining the real time physiological responses of glial cells in spinal sensory processing, sensitization, hyperalgesia and chronic pain.

  8. High plasticity in epithelial morphogenesis during insect dorsal closure

    Directory of Open Access Journals (Sweden)

    Kristen A. Panfilio

    2013-09-01

    Insect embryos complete the outer form of the body via dorsal closure (DC of the epidermal flanks, replacing the transient extraembryonic (EE tissue. Cell shape changes and morphogenetic behavior are well characterized for DC in Drosophila, but these data represent a single species with a secondarily reduced EE component (the amnioserosa that is not representative across the insects. Here, we examine DC in the red flour beetle, Tribolium castaneum, providing the first detailed, functional analysis of DC in an insect with complete EE tissues (distinct amnion and serosa. Surprisingly, we find that differences between Drosophila and Tribolium DC are not restricted to the EE tissue, but also encompass the dorsal epidermis, which differs in cellular architecture and method of final closure (zippering. We then experimentally manipulated EE tissue complement via RNAi for Tc-zen1, allowing us to eliminate the serosa and still examine viable DC in a system with a single EE tissue (the amnion. We find that the EE domain is particularly plastic in morphogenetic behavior and tissue structure. In contrast, embryonic features and overall kinetics are robust to Tc-zen1RNAi manipulation in Tribolium and conserved with a more distantly related insect, but remain substantially different from Drosophila. Although correct DC is essential, plasticity and regulative, compensatory capacity have permitted DC to evolve within the insects. Thus, DC does not represent a strong developmental constraint on the nature of EE development, a property that may have contributed to the reduction of the EE component in the fly lineage.

  9. Kinesthetic working memory and action control within the dorsal stream.

    Science.gov (United States)

    Fiehler, Katja; Burke, Michael; Engel, Annerose; Bien, Siegfried; Rösler, Frank

    2008-02-01

    There is wide agreement that the "dorsal (action) stream" processes visual information for movement control. However, movements depend not only on vision but also on tactile and kinesthetic information (=haptics). Using functional magnetic resonance imaging, the present study investigates to what extent networks within the dorsal stream are also utilized for kinesthetic action control and whether they are also involved in kinesthetic working memory. Fourteen blindfolded participants performed a delayed-recognition task in which right-handed movements had to be encoded, maintained, and later recognized without any visual feedback. Encoding of hand movements activated somatosensory areas, superior parietal lobe (dorsodorsal stream), anterior intraparietal sulcus (aIPS) and adjoining areas (ventrodorsal stream), premotor cortex, and occipitotemporal cortex (ventral stream). Short-term maintenance of kinesthetic information elicited load-dependent activity in the aIPS and adjacent anterior portion of the superior parietal lobe (ventrodorsal stream) of the left hemisphere. We propose that the action representation system of the dorsodorsal and ventrodorsal stream is utilized not only for visual but also for kinesthetic action control. Moreover, the present findings demonstrate that networks within the ventrodorsal stream, in particular the left aIPS and closely adjacent areas, are also engaged in working memory maintenance of kinesthetic information.

  10. Patella dislocation with vertical axis rotation: the "dorsal fin" patella.

    Science.gov (United States)

    Gamble, David; Otto, Quentin; Carrothers, Andrew D; Khanduja, Vikas

    2015-01-01

    A 44-year-old woman presented following minor trauma to her right knee. While dancing she externally rotated around a planted foot and felt sudden pain in her right knee. She presented with her knee locked in extension with a "dorsal fin" appearance of the soft tissues tented over the patella. This was diagnosed as a rare case of an intraarticular patella dislocation, which was rotated 90 degrees about the vertical axis. Closed reduction in the emergency room was unsuccessful but was achieved in theatre under general anaesthetic with muscle relaxation. Postreduction arthroscopy demonstrated that no osteochondral or soft tissue damage to the knee had been sustained. In patients presenting with a knee locked in extension with tenting of skin over the patella (the "dorsal fin" appearance), intra-articular patella dislocation should be suspected. Attempts to reduce vertical patella dislocations under sedation with excessive force or repeatedly without success should be avoided to prevent unnecessary damage to the patellofemoral joint. In this clinical situation we recommend closed reduction under general anaesthetic followed by immediate knee arthroscopy under the same anaesthetic to ensure that there is no chondral damage to the patella or femoral trochlea and to rule out an osteochondral fracture.

  11. Morphology of the dorsal and lateral calcaneocuboid ligaments.

    Science.gov (United States)

    Dorn-Lange, Nadja V; Nauck, Tanja; Lohrer, Heinz; Arentz, Sabine; Konerding, Moritz A

    2008-09-01

    The dorsolateral calcaneocuboid ligaments have different configurations. In the literature they are only described as either the dorsal or lateral calcaneocuboid ligament. However, recent reconstructive surgical techniques may benefit from a better understanding of the anatomy. The aims of this study were to classify the morphology and attachments of the dorso-lateral calcaneocuboid ligaments and to determine their dimensions. The dorso-lateral aspects of the calcaneocuboid joint of 30 cadaver feet were dissected to expose the associated ligaments. Further, we evaluated possible bony landmarks of the calcaneus that could imply which shape or course the ligament would have in a specific individual. Our findings showed a wide variety of configurations in shape, number, and attachment sites. A constant dorsal ligament and an additional narrower lateral ligament was detectable in half of the cases. The majority of the dorso-lateral calcaneocuboid ligament-complex had an upward course and fanning out from proximal to distal. No bony predictor for the ligaments' shape or course was found. The dorso-lateral ligament-complex of the calcaneocuboid joint revealed a wide variety of configurations. Better understanding of the anatomy of these ligaments may aid in the anatomic reconstruction of these ligaments.

  12. Retinal glia promote dorsal root ganglion axon regeneration.

    Directory of Open Access Journals (Sweden)

    Barbara Lorber

    Full Text Available Axon regeneration in the adult central nervous system (CNS is limited by several factors including a lack of neurotrophic support. Recent studies have shown that glia from the adult rat CNS, specifically retinal astrocytes and Müller glia, can promote regeneration of retinal ganglion cell axons. In the present study we investigated whether retinal glia also exert a growth promoting effect outside the visual system. We found that retinal glial conditioned medium significantly enhanced neurite growth and branching of adult rat dorsal root ganglion neurons (DRG in culture. Furthermore, transplantation of retinal glia significantly enhanced regeneration of DRG axons past the dorsal root entry zone after root crush in adult rats. To identify the factors that mediate the growth promoting effects of retinal glia, mass spectrometric analysis of retinal glial conditioned medium was performed. Apolipoprotein E and secreted protein acidic and rich in cysteine (SPARC were found to be present in high abundance, a finding further confirmed by western blotting. Inhibition of Apolipoprotein E and SPARC significantly reduced the neuritogenic effects of retinal glial conditioned medium on DRG in culture, suggesting that Apolipoprotein E and SPARC are the major mediators of this regenerative response.

  13. Environmental enrichment increases transcriptional and epigenetic differentiation between mouse dorsal and ventral dentate gyrus.

    Science.gov (United States)

    Zhang, Tie-Yuan; Keown, Christopher L; Wen, Xianglan; Li, Junhao; Vousden, Dulcie A; Anacker, Christoph; Bhattacharyya, Urvashi; Ryan, Richard; Diorio, Josie; O'Toole, Nicholas; Lerch, Jason P; Mukamel, Eran A; Meaney, Michael J

    2018-01-19

    Early life experience influences stress reactivity and mental health through effects on cognitive-emotional functions that are, in part, linked to gene expression in the dorsal and ventral hippocampus. The hippocampal dentate gyrus (DG) is a major site for experience-dependent plasticity associated with sustained transcriptional alterations, potentially mediated by epigenetic modifications. Here, we report comprehensive DNA methylome, hydroxymethylome and transcriptome data sets from mouse dorsal and ventral DG. We find genome-wide transcriptional and methylation differences between dorsal and ventral DG, including at key developmental transcriptional factors. Peripubertal environmental enrichment increases hippocampal volume and enhances dorsal DG-specific differences in gene expression. Enrichment also enhances dorsal-ventral differences in DNA methylation, including at binding sites of the transcription factor NeuroD1, a regulator of adult neurogenesis. These results indicate a dorsal-ventral asymmetry in transcription and methylation that parallels well-known functional and anatomical differences, and that may be enhanced by environmental enrichment.

  14. Comparação da ativação mioelétrica do glúteo máximo e bíceps femoral entre os agachamentos paralelo e com passada à frente Comparación de la activación mioeléctrica de los glúteos y bíceps femoral entre las sentadillas con los pies paralelos y los pies uno frente al otro Comparison of myoelectric activity of gluteus maximus and biceps femoris between parallel and lunge squat

    Directory of Open Access Journals (Sweden)

    Gustavo Leporace

    2012-09-01

    Full Text Available O objetivo desse estudo foi comparar a atividade mioelétrica (EMG do glúteo máximo e bíceps femoral entre o agachamento com passada à frente e com pés paralelos. Sete indivíduos realizaram oito repetições do agachamento paralelo (AP e com passada à frente (AF deslocando sobrecarga relativa a 50% da massa corporal. O EMG do glúteo máximo e bíceps femoral foi capturado, filtrado por um filtro passa-banda Butterworth de 4ª ordem (20-400 Hz e obtido valores RMS. Utilizou-se o teste de Wilcoxon para comparar o EMG normalizado entre os dois exercícios. Tanto o bíceps femoral (p = 0,041 quanto o glúteo máximo (p = 0,0059 apresentaram maior ativação no AF (30,9% para glúteo; 42,6% para bíceps em comparação ao AP (21,2% para glúteo; 24,7% para bíceps. Apesar da ativação moderada durante a execução dos exercícios, girando em torno de 25% a 45%, a resposta foi maior, para os participantes do estudo, no AF.El objetivo de este estudio fue comparar la actividad mioeléctrica (EMG del músculo glúteo mayor y el bíceps femoral entre la sentadilla con los pies uno frente al otro y los pies paralelos. Siete sujetos realizaron ocho repeticiones de la sentadilla paralela (AP y con los pies uno frente al otro (FA desplazando una masa igual a 50% del peso corporal. El EMG del músculo glúteo mayor y el bíceps femoral fueron capturados, filtrada por un filtro de banda de 4 º orden Butterworth (20-400 Hz y los valores RMS obtenidos. Se utilizó el test de Wilcoxon para comparar la EMG normalizada entre los dos ejercicios. Tanto el bíceps femoral (p = 0,041 y el glúteo mayor (p = 0,0059 mostraron una mayor activación en la FA (30,9% para lo glúteo y 52% para lo bíceps en comparación con el AP (21,2% para lo glúteo y 24,7% para lo bíceps. Aunque la activación moderada durante la ejecución de los ejercicios fue moderado, situándose en torno a un 25% a 45%, la respuesta fue mayor en el FA para los participantes del estudio

  15. Imperative, irony and smuggling of the pie in the sky. Somenotes on the poem Do Jeruszalaim by Jerzy Ficowski

    Directory of Open Access Journals (Sweden)

    Paulina Czwordon

    2009-01-01

    Full Text Available The poem Do Jeruszalaim combines different original poetical solutionsapplied in the collection of poems Odczytanie popiołów and rememberingthe experience of Shoah. The language of the poem becomes a toolemployed in a “smuggling” of unsaved Jews, being done “belatedly”,into the world of the living. Complicated, unspectacular by design,constructional operations are finely tuned with the semantics of the escape(flight and are to lay a false trail, to rescue a human being in theintricacies of the poem, somewhere between the sheer physics of theescape and the possibilities offered by words. A particularly interestingplace is given to the phraseological units used in the poems such as“a handful of pies in the sky” that simultaneously recall futility of theaction but somehow suggest a “smuggling” the act of life-giving activity.The activities carried out in the language of the poem functionin a ceaseless (and self-augmenting strain between the two contradictions.They are: the imperative of memory, impractical (and unfeasibleact of saving human “after-being” and the protest against the abyssmalnothingness of Shoah on the one hand, and irony of the futility of these“vindications from non-existence” as being only verbal, on the other.

  16. Foveolar Müller Cells of the Pied Flycatcher: Morphology and Distribution of Intermediate Filaments Regarding Cell Transparency.

    Science.gov (United States)

    Zueva, Lidia; Golubeva, Tatiana; Korneeva, Elena; Makarov, Vladimir; Khmelinskii, Igor; Inyushin, Mikhail

    2016-04-01

    Specialized intermediate filaments (IFs) have critical importance for the clearness and uncommon transparency of vertebrate lens fiber cells, although the physical mechanisms involved are poorly understood. Recently, an unusual low-scattering light transport was also described in retinal Müller cells. Exploring the function of IFs in Müller cells, we have studied the morphology and distribution pattern of IFs and other cytoskeletal filaments inside the Müller cell main processes in the foveolar part of the avian (pied flycatcher) retina. We found that some IFs surrounded by globular nanoparticles (that we suggest are crystallines) are present in almost every part of the Müller cells that span the retina, including the microvilli. Unlike IFs implicated in the mechanical architecture of the cell, these IFs are not connected to any specific cellular membranes. Instead, they are organized into bundles, passing inside the cell from the endfeet to the photoreceptor, following the geometry of the processes, and repeatedly circumventing numerous obstacles. We believe that the presently reported data effectively confirm that the model of nanooptical channels built of the IFs may provide a viable explanation of Müller cell transparency.

  17. Effects of pollution on land snail abundance, size and diversity as resources for pied flycatcher, Ficedula hypoleuca.

    Science.gov (United States)

    Eeva, Tapio; Rainio, Kalle; Suominen, Otso

    2010-09-01

    Passerine birds need extra calcium during their breeding for developing egg shells and proper growth of nestling skeleton. Land snails are an important calcium source for many passerines and human-induced changes in snail populations may pose a severe problem for breeding birds. We studied from the bird's viewpoint how air pollution affects the shell mass, abundance and diversity of land snail communities along a pollution gradient of a copper smelter. We sampled remnant snail shells from the nests of an insectivorous passerine, the pied flycatcher, Ficedula hypoleuca, to find out how the availability of land snails varies along the pollution gradient. The total snail shell mass increased towards the pollution source but declined abruptly in the vicinity of the smelter. This spatial variation in shell mass was evident also within a single snail species and could not be wholly explained by spatially varying snail numbers or species composition. Instead, the total shell mass was related to their shell size, individuals being largest at the moderately polluted areas. Smaller shell size suggests inferior growth of snails in the most heavily polluted area. Our study shows that pollution affects the diversity, abundance (available shell mass) and individual quality of land snails, posing reproductive problems for birds that rely on snails as calcium sources during breeding. There are probably both direct pollution-related (heavy metal and calcium levels) and indirect (habitat change) effects behind the observed changes in snail populations. Copyright 2010 Elsevier B.V. All rights reserved.

  18. [The crooked nose: correction of dorsal and caudal septal deviations].

    Science.gov (United States)

    Foda, H M T

    2010-09-01

    The deviated nose represents a complex cosmetic and functional problem. Septal surgery plays a central role in the successful management of the externally deviated nose. This study included 800 patients seeking rhinoplasty to correct external nasal deviations; 71% of these suffered from variable degrees of nasal obstruction. Septal surgery was necessary in 736 (92%) patients, not only to improve breathing, but also to achieve a straight, symmetric external nose. A graduated surgical approach was adopted to allow correction of the dorsal and caudal deviations of the nasal septum without weakening its structural support to the nasal dorsum or nasal tip. The approach depended on full mobilization of deviated cartilage, followed by straightening of the cartilage and its fixation in the corrected position by using bony splinting grafts through an external rhinoplasty approach.

  19. Direct dorsal hippocampal-prelimbic cortex connections strengthen fear memories.

    Science.gov (United States)

    Ye, Xiaojing; Kapeller-Libermann, Dana; Travaglia, Alessio; Inda, M Carmen; Alberini, Cristina M

    2017-01-01

    The ability to regulate the consolidation and strengthening of memories for threatening experiences is critical for mental health, and its dysregulation may lead to psychopathologies. Re-exposure to the context in which the threat was experienced can either increase or decrease fear response through distinct processes known, respectively, as reconsolidation or extinction. Using a context retrieval-dependent memory-enhancement model in rats, we report that memory strengthens through activation of direct projections from dorsal hippocampus to prelimbic (PL) cortex and activation of critical PL molecular mechanisms that are not required for extinction. Furthermore, while sustained PL brain-derived neurotrophic factor (BDNF) expression is required for memory consolidation, retrieval engages PL BDNF to regulate excitatory and inhibitory synaptic proteins neuroligin 1 and neuroligin 2, which promote memory strengthening while inhibiting extinction. Thus, context retrieval-mediated fear-memory enhancement results from a concerted action of mechanisms that strengthen memory through reconsolidation while suppressing extinction.

  20. Dorsal Raphe Dopamine Neurons Represent the Experience of Social Isolation

    Science.gov (United States)

    Matthews, Gillian A.; Nieh, Edward H.; Vander Weele, Caitlin M.; Halbert, Sarah A.; Pradhan, Roma V.; Yosafat, Ariella S.; Glober, Gordon F.; Izadmehr, Ehsan M.; Thomas, Rain E.; Lacy, Gabrielle D.; Wildes, Craig P.; Ungless, Mark A.; Tye, Kay M.

    2016-01-01

    Summary The motivation to seek social contact may arise from either positive or negative emotional states, as social interaction can be rewarding and social isolation can be aversive. While ventral tegmental area (VTA) dopamine (DA) neurons may mediate social reward, a cellular substrate for the negative affective state of loneliness has remained elusive. Here, we identify a functional role for DA neurons in the dorsal raphe nucleus (DRN), in which we observe synaptic changes following acute social isolation. DRN DA neurons show increased activity upon social contact following isolation, revealed by in vivo calcium imaging. Optogenetic activation of DRN DA neurons increases social preference but causes place avoidance. Furthermore, these neurons are necessary for promoting rebound sociability following an acute period of isolation. Finally, the degree to which these neurons modulate behavior is predicted by social rank, together supporting a role for DRN dopamine neurons in mediating a loneliness-like state. PaperClip PMID:26871628

  1. Spinal dorsal horn astrocytes: New players in chronic itch

    Directory of Open Access Journals (Sweden)

    Makoto Tsuda

    2017-01-01

    Full Text Available Chronic itch is a debilitating symptom of inflammatory skin conditions, such as atopic dermatitis, and systemic diseases, for which existing treatment is largely ineffective. Recent studies have revealed the selective neuronal pathways that are involved in itch sensations; however, the mechanisms by which itch turns into a pathological chronic state are poorly understood. Recent advances in our understanding of the mechanisms producing chronic itch have been made by defining causal roles for astrocytes in the spinal dorsal horn in mouse models of chronic itch including atopic dermatitis. Understanding the key roles of astrocytes may provide us with exciting insights into the mechanisms for itch chronicity and lead to a previously unrecognized target for treating chronic itch.

  2. The presence of nuclear cactus in the early Drosophila embryo may extend the dynamic range of the dorsal gradient.

    Directory of Open Access Journals (Sweden)

    Michael D O'Connell

    2015-04-01

    Full Text Available In a developing embryo, the spatial distribution of a signaling molecule, or a morphogen gradient, has been hypothesized to carry positional information to pattern tissues. Recent measurements of morphogen distribution have allowed us to subject this hypothesis to rigorous physical testing. In the early Drosophila embryo, measurements of the morphogen Dorsal, which is a transcription factor responsible for initiating the earliest zygotic patterns along the dorsal-ventral axis, have revealed a gradient that is too narrow to pattern the entire axis. In this study, we use a mathematical model of Dorsal dynamics, fit to experimental data, to determine the ability of the Dorsal gradient to regulate gene expression across the entire dorsal-ventral axis. We found that two assumptions are required for the model to match experimental data in both Dorsal distribution and gene expression patterns. First, we assume that Cactus, an inhibitor that binds to Dorsal and prevents it from entering the nuclei, must itself be present in the nuclei. And second, we assume that fluorescence measurements of Dorsal reflect both free Dorsal and Cactus-bound Dorsal. Our model explains the dynamic behavior of the Dorsal gradient at lateral and dorsal positions of the embryo, the ability of Dorsal to regulate gene expression across the entire dorsal-ventral axis, and the robustness of gene expression to stochastic effects. Our results have a general implication for interpreting fluorescence-based measurements of signaling molecules.

  3. Selective resection of dorsal nerves of penis for premature ejaculation.

    Science.gov (United States)

    Zhang, G-X; Yu, L-P; Bai, W-J; Wang, X-F

    2012-12-01

    Premature ejaculation (PE) is one of the most prevalent male sexual dysfunctions. Selective resection of the dorsal nerve (SRDN) of penis has recently been used for the treatment of PE and has shown some efficacy. To further clarify the efficacy and safety of SRDN on PE, we performed a preliminary, randomized, placebo-controlled clinical observational study. Persons with the complaints of rapid ejaculation, asking for circumcision because of redundant foreskin, intravaginal ejaculation latency time (IELT) within 2 min, not responding to antidepressant medication or disliking oral medication were randomly enrolled in two groups. From April 2007 to August 2010, a total of 101 eligible persons were enrolled, 40 of them received SRDN which dorsal nerves of the penis were selectively resected, and those (n = 61) enrolled in the control group were circumcised only. IELT and the Brief Male Sexual Function Inventory (BMSFI) questionnaire were implemented pre- and post-operatively for the evaluation of the effect and safety of the surgery. There are no statistically significant differences in the baseline data including mean ages, mean IELTs, perceived control abilities and the BMSFI mean scores between the two groups. With regard to the post-operative data of the surgery, both IELTs and perceived control abilities were significantly increased after SRDN (1.1 ± 0.9 min vs. 3.8 ± 3.1 min for pre- and post-operative IELT, respectively, p 0.05). Also, there were no statistically significant differences both in BMSFI composite and subscale scores between the two groups after surgery. Hence, we conclude that SRDN is effective in delaying ejaculation and improving ejaculatory control, whereas erectile function is not affected. The results imply that SRDN may be an alternative method for the treatment of PE for some patients. © 2012 The Authors. International Journal of Andrology © 2012 European Academy of Andrology.

  4. Investigación del conglomerado colapsable de la Cano-Vitor Arequipa

    OpenAIRE

    Fernández Sixto, Erasmo Alejandro; Fernández Sixto, Erasmo Alejandro

    1998-01-01

    El conocimiento de la existencia de suelos compuestos por un conglomerado de partículas gruesas (gravas, guijarros y botones) embebidos dentro de una matriz de partículas menores (arenas, limos y arcillas), que posee un comportamiento colapsable; no tiene precedentes en el Perú a excepción de la advertencia señalada por el profesor Alberto Martínez Vargas (1980). Justamente el mencionado investigador atribuyó al suelo de la formación Sotillo localizado en la escarpa del Pie de la Cuesta en el...

  5. Desempenho de cordeiros alimentados com inclusão de torta de macaúba na dieta Performance of lambs fed with macauba pie inclusion in the diet

    Directory of Open Access Journals (Sweden)

    Rafael Alves de Azevedo

    2012-11-01

    Full Text Available O objetivo deste trabalho foi avaliar o consumo de nutrientes e o desempenho produtivo e econômico de ovinos confinados da raça Santa Inês, alimentados com dietas com diferentes taxas de inclusão de torta de macaúba. Os animais (24 foram distribuídos em delineamento de blocos ao acaso, nos tratamentos com 0, 100, 200 e 300 g kg-1 de torta de macaúba na matéria seca da dieta, em seis repetições, durante 60 dias de confinamento. A adição de torta de macaúba a taxas crescentes à dieta aumentou linearmente o consumo de proteína bruta, extrato etéreo, fibra em detergente neutro e a conversão alimentar. Não houve diferença no consumo de matéria seca, ganho médio diário e ganho de peso vivo total com a adição da torta. O tratamento com inclusão de 100 g kg-1 apresentou a melhor relação custo:benefício na avaliação das receitas bruta e líquida obtidas com a venda dos animais vivos e abatidos. A adição da torta de macaúba em até 300 g kg-1 da dieta não altera o desempenho produtivo dos animais, entretanto, a inclusão de 100 g kg-1 proporciona melhor retorno econômico.The objective of this work was to evaluate the nutrient uptake and the productive and economic performance of confined Santa Inês lambs fed diets with different levels of macauba pie inclusion . The animals (24 were distributed in a randomized block design, in treatments with 0, 100, 200 and 300 g kg-1 macauba pie in the diet dry matter, with six replicates during 60 days of confinement. The addition of macauba pie at increasing rates to the diet linearly increased the intake of crude protein, ether extract, neutral detergent fiber and feed conversion. There was no difference in dry matter intake, average daily gain and total live weight gain with the macauba pie addition. Diet with 100 g kg-1 macauba pie inclusion showed the best cost:benefit ratio in the evaluation of gross and net revenues from the sale of live and slaughtered animals. The addition

  6. Motor deficits following dorsal corticospinal tract transection in rats: voluntary versus skilled locomotion readouts

    Directory of Open Access Journals (Sweden)

    Lara Bieler

    2018-02-01

    The functional relevance of the dorsal CST in locomotion of rats is not as prominent as compared to in humans and thus challenging the motor execution is mandatory to reliably investigate CST function. A detailed analysis of voluntary walking using the CatWalk XT is not adequate to detect deficits following dorsal CST lesion in rats.

  7. The function of the long dorsal sacroiliac ligament : its implications for understanding low back pain

    NARCIS (Netherlands)

    Pool-Goudzwaard, A.L.; Vleeming, A; Hammudoghlu, D; Stoeckart, R.; Snijders, C.; Mens, Jan M A

    1996-01-01

    STUDY DESIGN: In embalmed human bodies the tension of the long dorsal sacroiliac ligament was measured during incremental loading of anatomical structures that are biomechanically relevant. OBJECTIVES: To assess the function of the long dorsal sacroiliac ligament. SUMMARY OF BACKGROUND DATA: In many

  8. Role of the right dorsal anterior insula in the urge to tic in Tourette syndrome.

    Science.gov (United States)

    Tinaz, Sule; Malone, Patrick; Hallett, Mark; Horovitz, Silvina G

    2015-08-01

    The mid-posterior part of the insula is involved in processing bodily sensations and urges and is activated during tic generation in Tourette syndrome. The dorsal anterior part of the insula, however, integrates sensory and emotional information with cognitive valuation and is implicated in interoception. The right dorsal anterior insula also participates in urge suppression in healthy subjects. This study examined the role of the right dorsal anterior insula in the urge to tic in Tourette syndrome. Resting-state functional magnetic resonance imaging was performed in 13 adult Tourette patients and 13 matched controls. The role of the right dorsal anterior insula within the urge-tic network was investigated using graph theory-based neural network analysis. The functional connectivity of the right dorsal anterior insula was also correlated with urge and tic severity. Even though the patients did not exhibit any overt tics, the right dorsal anterior insula demonstrated higher connectivity, especially with the frontostriatal nodes of the urge-tic network in patients compared with controls. The functional connectivity between the right dorsal anterior insula and bilateral supplementary motor area also correlated positively with urge severity in patients. These results suggest that the right dorsal anterior insula is part of the urge-tic network and could influence the urge- and tic-related cortico-striato-thalamic regions even during rest in Tourette syndrome. It might be responsible for heightened awareness of bodily sensations generating premonitory urges in Tourette syndrome. © 2015 International Parkinson and Movement Disorder Society.

  9. The ventral stream offers more affordance and the dorsal stream more memory than believed

    NARCIS (Netherlands)

    Postma, Albert; van der Lubbe, Robert Henricus Johannes; Zuidhoek, Sander

    2002-01-01

    Opposed to Norman's proposal, processing of affordance is likely to occur not solely in the dorsal stream but also in the ventral stream. Moreover, the dorsal stream might do more than just serve an important role in motor actions. It supports egocentric location coding as well. As such, it would

  10. Monosynaptic connections between primary afferents and giant neurons in the turtle spinal dorsal horn

    DEFF Research Database (Denmark)

    Fernández, A; Radmilovich, M; Russo, R E

    1996-01-01

    This paper reports the occurrence of monosynaptic connections between dorsal root afferents and a distinct cell type-the giant neuron-deep in the dorsal horn of the turtle spinal cord. Light microscope studies combining Nissl stain and transganglionic HRP-labeling of the primary afferents have...

  11. Actrices del cine mudo que no superaron la barrera del sonoro

    Directory of Open Access Journals (Sweden)

    Rosa María Ballesteros García

    2016-10-01

    Full Text Available El presente artículo tiene como objetivo recuperar una serie de actrices, ídolos de la etapa del cine mudo, que no lograron mantenerse al iniciarse el proceso al hablado. Ponemos el objetivo en algunas de las actrices más representativas a quienes el progreso técnico iba a condenar al ostracismo al no adecuarse su voz (aún sin la muleta del doblaje a los inevitables cambios estructurales y auditivos. En los años en que se produce esta transición (último tercio de 1920 y primeros años de 1930 se produjo un general “pánico” entre el colectivo, justificado por cierto, pues a partir de entonces fueron de estricta obligación las “pruebas de voz”, por lo que buena parte de estas glorias mudas vieron frustradas sus carreras. Ídolos con pies de barro, juguetes a merced del marketing y de la voracidad de los productores, sus nombres fueron difuminándose, tan rápido como habían sido encumbrados, en una involuntaria huida plagada de fracasos, de adiciones y de varios casos de suicidios.

  12. [Disseminated metastatic tumor at dorsal surface of medulla oblongata presenting intractable hiccups. A case report].

    Science.gov (United States)

    Arishima, Hidetaka; Kikuta, Ken-ichirou

    2011-04-01

    We report the case of disseminated metastatic tumor at dorsal surface of medulla oblongata presenting intractable hiccups. A 73-year-old man has a history of for metastatic lung tumor of the left tempral lobe. Although 3 surgeries and 4 radiotherapies were performed in the last 8 years, residual tumor grew slowly. He presented with intractable hiccups. His hiccups continued for 30 minutes, sometimes for 3 hours with obstruction of eating. Contrast-enhanced Magnetic resonance (MR) imaging demonstrated the dissemination of metastatic lung tumor at dorsal surface of medulla oblongata and ventral surface of midbrain. Some literatures reported the patients with intractable hiccups caused by dorsal medullary lesions. Therefore, we thought that the small disseminated tumor at dorsal surface of medulla oblongata caused the hiccups. Evaluation of dorsal medullay area by MR imaging is important to reveal the cause of intractable hiccups.

  13. Amnioserosa cell constriction but not epidermal actin cable tension autonomously drives dorsal closure.

    Science.gov (United States)

    Pasakarnis, Laurynas; Frei, Erich; Caussinus, Emmanuel; Affolter, Markus; Brunner, Damian

    2016-11-01

    Tissue morphogenesis requires coordination of multiple force-producing components. During dorsal closure in fly embryogenesis, an epidermis opening closes. A tensioned epidermal actin/MyosinII cable, which surrounds the opening, produces a force that is thought to combine with another MyosinII force mediating apical constriction of the amnioserosa cells that fill the opening. A model proposing that each force could autonomously drive dorsal closure was recently challenged by a model in which the two forces combine in a ratchet mechanism. Acute force elimination via selective MyosinII depletion in one or the other tissue shows that the amnioserosa tissue autonomously drives dorsal closure while the actin/MyosinII cable cannot. These findings exclude both previous models, although a contribution of the ratchet mechanism at dorsal closure onset remains likely. This shifts the current view of dorsal closure being a combinatorial force-component system to a single tissue-driven closure event.

  14. Control del deterioro de la madera mediante la acción de nano-impregnantes y recubrimientos sol-gel a base de silanos

    OpenAIRE

    Alfieri, Paula Vanesa

    2018-01-01

    El aumento constante del consumo de madera como material ha llevado a la necesidad de introducir en el mercado especies de crecimiento rápido las cuales poseen propiedades inferiores desde el punto de vista de la resistencia a la degradación. La extracción de madera en el pasado fue indiscriminada, sin medir las consecuencias del deterioro de los bosques naturales; se extraían grandes volúmenes de madera de crecimiento lento, que demoraban siglos en madurar, dejando en pie aquellos árboles de...

  15. Evaluación del impacto de las actividades intergeneracionales programadas en el Programa Interuniversitario de la Experiencia de la Universidad de Burgos

    OpenAIRE

    Jiménez Eguizábal, Alfredo; Luis Rico, María Isabel; Palmero Cámara, Carmen

    2011-01-01

    En una sociedad cada vez más envejecida toman importancia los factores determinantes del envejecimiento activo, tales como el aprendizaje a lo largo de la vida y las actividades intergeneracionales. Desde la Universidad de Burgos y dentro del Programa Interuniversitario de la Experiencia (PIE) se ha diseñado y aplicado un Programa Intergeneracional (PI) entre los alumnos mayores universitarios y los jóvenes estudiantes de la Universidad, centrado en el valor mutuo de la comunicación intergene...

  16. A randomized controlled trial of a manual-based psychosocial group intervention for young people with epilepsy [PIE].

    Science.gov (United States)

    Dorris, Liam; Broome, Helen; Wilson, Margaret; Grant, Cathy; Young, David; Baker, Gus; Balloo, Selina; Bruce, Susan; Campbell, Jo; Concannon, Bernie; Conway, Nadia; Cook, Lisa; Davis, Cheryl; Downey, Bruce; Evans, Jon; Flower, Diane; Garlovsky, Jack; Kearney, Shauna; Lewis, Susan; Stephens, Victoria; Turton, Stuart; Wright, Ingram

    2017-07-01

    We conducted an exploratory RCT to examine feasibility and preliminary efficacy for a manual-based psychosocial group intervention aimed at improving epilepsy knowledge, self-management skills, and quality of life in young people with epilepsy. Eighty-three participants (33:50m/f; age range 12-17years) were randomized to either the treatment or control group in seven tertiary paediatric neuroscience centres in the UK, using a wait-list control design. Participants were excluded if they reported suicidal ideation and/or scored above the cut off on mental health screening measures, or if they had a learning disability or other neurological disorder. The intervention consisted of six weekly 2-hour sessions using guided discussion, group exercises and role-plays facilitated by an epilepsy nurse and a clinical psychologist. At three month follow up the treatment group (n=40) was compared with a wait-list control group (n=43) on a range of standardized measures. There was a significant increase in epilepsy knowledge in the treatment group (p=0.02). Participants receiving the intervention were also significantly more confident in speaking to others about their epilepsy (p=0.04). Quality of life measures did not show significant change. Participants reported the greatest value of attending the group was: Learning about their epilepsy (46%); Learning to cope with difficult feelings (29%); and Meeting others with epilepsy (22%). Caregiver and facilitator feedback was positive, and 92% of participants would recommend the group to others. This brief psychosocial group intervention was effective in increasing participants' knowledge of epilepsy and improved confidence in discussing their epilepsy with others. We discuss the qualitative feedback, feasibility, strengths and limitations of the PIE trial. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. Oxidative Stress in Early Life: Associations with Sex, Rearing Conditions, and Parental Physiological Traits in Nestling Pied Flycatchers.

    Science.gov (United States)

    López-Arrabé, Jimena; Cantarero, Alejandro; Pérez-Rodríguez, Lorenzo; Palma, Antonio; Moreno, Juan

    2016-01-01

    Conditions experienced during juvenile development can affect the fitness of an organism. During early life, oxidative stress levels can be particularly high as a result of the increased metabolism and the relatively immature antioxidant system of the individual, and this may have medium- and long-term fitness consequences. Here we explore variation in levels of oxidative stress measured during early life in relation to sex, rearing conditions (hatching date and brood size), and parental condition and levels of oxidative markers in a wild population of the pied flycatcher (Ficedula hypoleuca) followed for 2 yr. A marker of total antioxidant status (TAS) in plasma and total levels of glutathione (GSH) in red blood cells, as well as a marker of oxidative damage in plasma lipids (malondialdehyde [MDA]), were assessed simultaneously. Our results show that nestling total GSH levels were associated with parental oxidative status, correlating negatively with maternal MDA and positively with total GSH levels of both parents, with a high estimated heritability. This suggests that parental physiology and genes could be determinants for endogenous components of the antioxidant system of the offspring. Moreover, we found that total GSH levels were higher in female than in male nestlings and that hatching date was positively associated with antioxidant defenses (higher TAS and total GSH levels). These results suggest that different components of oxidative balance are related to a variety of environmental and intrinsic--including parental--influencing factors. Future experimental studies must disentangle the relative contribution of each of these on nestling oxidative status and how the resulting oxidative stress at early phases shape adult phenotype and fitness.

  18. Dorsal clitoral nerve injury following transobturator midurethral sling

    Directory of Open Access Journals (Sweden)

    Moss CF

    2016-09-01

    Full Text Available Chailee F Moss,1 Lynn A Damitz,2 Richard H Gracely,3 Alice C Mintz,3 Denniz A Zolnoun,2–4 A Lee Dellon5 1Department of Obstetrics and Gynecology, Ohio State University School of Medicine, Columbus, OH, USA; 2Department of Surgery, University of North Carolina at Chapel Hill, NC, USA; 3Department of Endodontics, University of North Carolina at Chapel Hill, NC, USA; 4Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA; 5Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA Introduction: Transobturator slings can be successfully used to treat stress urinary incontinence and improve quality of life through a minimally invasive vaginal approach. Persistent postoperative pain can occur and pose diagnostic and therapeutic dilemmas. Following a sling procedure, a patient complained of pinching clitoral and perineal pain. Her symptoms of localized clitoral pinching and pain became generalized over the ensuing years, eventually encompassing the entire left vulvovaginal region.Aim: The aim of this study was to highlight the clinical utility of conventional pain management techniques used for the evaluation and management of patients with postoperative pain following pelvic surgery. Methods: We described a prototypical patient with persistent pain in and around the clitoral region complicating the clinical course of an otherwise successful sling procedure. We specifically discussed the utility of bedside sensory assessment techniques and selective nerve blocks in the evaluation and management of this prototypical patient. Results: Neurosensory assessments and a selective nerve block enabled us to trace the source of the patient’s pain to nerve entrapment along the dorsal nerve of the clitoris. We then utilized a nerve stimulator-guided hydrodissection technique to release the scar contracture Conclusion: This case

  19. The Canonical Immediate Early 3 Gene Product pIE611 of Mouse Cytomegalovirus Is Dispensable for Viral Replication but Mediates Transcriptional and Posttranscriptional Regulation of Viral Gene Products.

    Science.gov (United States)

    Rattay, Stephanie; Trilling, Mirko; Megger, Dominik A; Sitek, Barbara; Meyer, Helmut E; Hengel, Hartmut; Le-Trilling, Vu Thuy Khanh

    2015-08-01

    Transcription of mouse cytomegalovirus (MCMV) immediate early ie1 and ie3 is controlled by the major immediate early promoter/enhancer (MIEP) and requires differential splicing. Based on complete loss of genome replication of an MCMV mutant carrying a deletion of the ie3-specific exon 5, the multifunctional IE3 protein (611 amino acids; pIE611) is considered essential for viral replication. Our analysis of ie3 transcription resulted in the identification of novel ie3 isoforms derived from alternatively spliced ie3 transcripts. Construction of an IE3-hemagglutinin (IE3-HA) virus by insertion of an in-frame HA epitope sequence allowed detection of the IE3 isoforms in infected cells, verifying that the newly identified transcripts code for proteins. This prompted the construction of an MCMV mutant lacking ie611 but retaining the coding capacity for the newly identified isoforms ie453 and ie310. Using Δie611 MCMV, we demonstrated the dispensability of the canonical ie3 gene product pIE611 for viral replication. To determine the role of pIE611 for viral gene expression during MCMV infection in an unbiased global approach, we used label-free quantitative mass spectrometry to delineate pIE611-dependent changes of the MCMV proteome. Interestingly, further analysis revealed transcriptional as well as posttranscriptional regulation of MCMV gene products by pIE611. Cytomegaloviruses are pathogenic betaherpesviruses persisting in a lifelong latency from which reactivation can occur under conditions of immunosuppression, immunoimmaturity, or inflammation. The switch from latency to reactivation requires expression of immediate early genes. Therefore, understanding of immediate early gene regulation might add insights into viral pathogenesis. The mouse cytomegalovirus (MCMV) immediate early 3 protein (611 amino acids; pIE611) is considered essential for viral replication. The identification of novel protein isoforms derived from alternatively spliced ie3 transcripts prompted

  20. Do dorsal raphe 5-HT neurons encode "beneficialness"?

    Science.gov (United States)

    Luo, Minmin; Li, Yi; Zhong, Weixin

    2016-11-01

    The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) affects numerous behavioral and physiological processes. Drugs that alter 5-HT signaling treat several major psychiatric disorders and may lead to widespread abuse. The dorsal raphe nucleus (DRN) in the midbrain provides a majority of 5-HT for the forebrain. The importance of 5-HT signaling propels the search for a general theoretical framework under which the diverse functions of the DRN 5-HT neurons can be interpreted and additional therapeutic solutions may be developed. However, experimental data so far support several seeming irreconcilable theories, suggesting that 5-HT neurons mediate behavioral inhibition, aversive processing, or reward signaling. Here, we review recent progresses and propose that DRN 5-HT neurons encode "beneficialness" - how beneficial the current environmental context represents for an individual. Specifically, we speculate that the activity of these neurons reflects the possible net benefit of the current context as determined by p·R-C, in which p indicates reward probability, R the reward value, and C the cost. Through the widespread projections of these neurons to the forebrain, the beneficialness signal may reconfigure neural circuits to bias perception, boost positive emotions, and switch behavioral choices. The "beneficialness" hypothesis can explain many conflicting observations, and at the same time raises new questions. We suggest additional experiments that will help elucidate the exact computational functions of the DRN 5-HT neurons. Copyright © 2016 Elsevier Inc. All rights reserved.

  1. Dorsal bridge plating or transarticular screws for Lisfranc fracture dislocations.

    Science.gov (United States)

    Kirzner, N; Zotov, P; Goldbloom, D; Curry, H; Bedi, H

    2018-04-01

    Aims The aim of this retrospective study was to compare the functional and radiological outcomes of bridge plating, screw fixation, and a combination of both methods for the treatment of Lisfranc fracture dislocations. Patients and Methods A total of 108 patients were treated for a Lisfranc fracture dislocation over a period of nine years. Of these, 38 underwent transarticular screw fixation, 45 dorsal bridge plating, and 25 a combination technique. Injuries were assessed preoperatively according to the Myerson classification system. The outcome measures included the American Orthopaedic Foot and Ankle Society (AOFAS) score, the validated Manchester Oxford Foot Questionnaire (MOXFQ) functional tool, and the radiological Wilppula classification of anatomical reduction. Results Significantly better functional outcomes were seen in the bridge plate group. These patients had a mean AOFAS score of 82.5 points, compared with 71.0 for the screw group and 63.3 for the combination group (p bridge plate group, 38.1 in the screw group, and 45.5 in the combination group (p bridge plating have better functional and radiological outcomes than those treated with transarticular screws or a combination technique. Cite this article: Bone Joint J 2018;100-B:468-74.

  2. Dorsal raphe nucleus projecting retinal ganglion cells: Why Y cells?

    Science.gov (United States)

    Pickard, Gary E.; So, Kwok-Fai; Pu, Mingliang

    2015-01-01

    Retinal ganglion Y (alpha) cells are found in retinas ranging from frogs to mice to primates. The highly conserved nature of the large, fast conducting retinal Y cell is a testament to its fundamental task, although precisely what this task is remained ill-defined. The recent discovery that Y-alpha retinal ganglion cells send axon collaterals to the serotonergic dorsal raphe nucleus (DRN) in addition to the lateral geniculate nucleus (LGN), medial interlaminar nucleus (MIN), pretectum and the superior colliculus (SC) has offered new insights into the important survival tasks performed by these cells with highly branched axons. We propose that in addition to its role in visual perception, the Y-alpha retinal ganglion cell provides concurrent signals via axon collaterals to the DRN, the major source of serotonergic afferents to the forebrain, to dramatically inhibit 5-HT activity during orientation or alerting/escape responses, which dis-facilitates ongoing tonic motor activity while dis-inhibiting sensory information processing throughout the visual system. The new data provide a fresh view of these evolutionarily old retinal ganglion cells. PMID:26363667

  3. The Molecular Fingerprint of Dorsal Root and Trigeminal Ganglion Neurons

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    Douglas M. Lopes

    2017-09-01

    Full Text Available The dorsal root ganglia (DRG and trigeminal ganglia (TG are clusters of cell bodies of highly specialized sensory neurons which are responsible for relaying information about our environment to the central nervous system. Despite previous efforts to characterize sensory neurons at the molecular level, it is still unknown whether those present in DRG and TG have distinct expression profiles and therefore a unique molecular fingerprint. To address this question, we isolated lumbar DRG and TG neurons using fluorescence-activated cell sorting from Advillin-GFP transgenic mice and performed RNA sequencing. Our transcriptome analyses showed that, despite being overwhelmingly similar, a number of genes are differentially expressed in DRG and TG neurons. Importantly, we identified 24 genes which were uniquely expressed in either ganglia, including an arginine vasopressin receptor and several homeobox genes, giving each population a distinct molecular fingerprint. We compared our findings with published studies to reveal that many genes previously reported to be present in neurons are in fact likely to originate from other cell types in the ganglia. Additionally, our neuron-specific results aligned well with a dataset examining whole human TG and DRG. We propose that the data can both improve our understanding of primary afferent biology and help contribute to the development of drug treatments and gene therapies which seek targets with unique or restricted expression patterns.

  4. DESCRIPCIÓN DE UN SISTEMA PARA LA MEDICIÓN DE LAS PRESIONES PLANTARES POR MEDIO DEL PROCESAMIENTO DE IMÁGENES: FASE I

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    Christian Andrés Díaz

    Full Text Available La medida de la presión plantar es fundamental para conocer la distribución de las fuerzas en la planta del pie. Estos valores son importantes para el diagnóstico y tratamiento de diferentes patologías como úlceras diabéticas en la planta del pie y presencia de deformidades en extremidades inferiores, entre otras. En el presente artículo se describe el desarrollo de un podobarógrafo para el análisis de la huella plantar, cuyo desarrollo incluyó la fabricación de un podoscopio, la selección de un material transductor adecuado y el desarrollo del software para el procesamiento de las imágenes capturadas por una cámara de video. El dispositivo propuesto PodoMED permite realizar un análisis dinámico y estático de la huella, pues aparte de mostrar cómo es la distribución de presiones en la planta del pie durante la marcha, por medio de imágenes en seudocolor, tiene la opción de emitir una valoración de la huella, donde se muestran medidas como el índice de valgo, el ángulo de Clarke, el índice de Hernández Corvo, entre otros. Para el desarrollo de este proyecto se realizaron ensayos experimentales para minimizar el ruido de la imagen, lo cual se logró con la utilización de un filtro físico y otro para la imagen por medio de software. Para una etapa futura, se planea la calibración y validación del sistema, con lo cual se pretende brindar mayor confiabilidad y repetibilidad.

  5. A biomechanical comparison of four fixed-angle dorsal plates in a finite element model of dorsally-unstable radius fracture.

    Science.gov (United States)

    Knežević, Josip; Kodvanj, Janoš; Čukelj, Fabijan; Pamuković, Frane; Pavić, Arsen

    2017-11-01

    To compare the finite element models of two different composite radius fracture patterns, reduced and stabilised with four different fixed-angle dorsal plates during axial, dorsal and volar loading conditions. Eight different plastic models representing four AO/ASIF type 23-A3 distal radius fractures and four AO/ASIF 23-C2 distal radius fractures were obtained and fixed each with 1 of 4 methods: a standard dorsal non-anatomical fixed angle T-plate (3.5mm Dorsal T-plate, Synthes), anatomical fixed-angle double plates (2.4mm LCP Dorsal Distal Radius, Synthes), anatomical fixed angle T-plate (2.4mm Acu-Loc Dorsal Plate, Acumed) or anatomical variable-angle dorsal T-plate (3.5mm, Dorsal Plate, Zrinski). Composite radius with plate and screws were scanned with a 3D optical scanner and later processed in Abaqus Software to generate the finite element model. All models were axially loaded at 3 points (centrally, volarly and dorsally) with 50 N forces to avoid the appearance of plastic deformations of the models. Total displacements at the end of the bone and the stresses in the bones and plates were determined and compared. Maximal von Mises stress in bone for 3-part fracture models was very similar to that in 2-part fracture models. The biggest difference between models and the largest displacements were seen during volar loading. The stresses in all models were the highest above the fracture gap. The best performance in all parameters tested was with the Zrinski plate and the most modest results were with the Synthes T-plate. There was no significant difference between 2-part (AO/ASIF type 23-A3) and 3-part (AO/ASIF 23-C2) fracture models. Maximal stresses in the plates appeared above the fracture gap; therefore, it is worth considering the development of plates without screw holes above the gap. © 2017 Elsevier Ltd. All rights reserved.

  6. Basal Cell Carcinoma of the Dorsal Hand: An Update and Comprehensive Review of the Literature.

    Science.gov (United States)

    Loh, Tiffany Y; Rubin, Ashley G; Brian Jiang, Shang I

    2016-04-01

    Excessive ultraviolet radiation (UVR) exposure is the primary predisposing factor for basal cell carcinoma (BCC). However, surprisingly, BCCs occur very rarely on the dorsal hand, which is subject to intense sun exposure, and their infrequent presentation in this location suggests that other factors besides UVR may play a role in BCC pathogenesis. Because dorsal hand BCCs are uncommon, knowledge of their characteristics is limited, and more data are needed to describe their clinical presentation and treatment. To perform an updated review of the literature on the management of dorsal hand BCCs. The authors conducted a comprehensive literature review by searching the PubMed database with the key phrases "basal cell carcinoma dorsal hand," "basal cell carcinoma hand," and "basal cell carcinoma finger," and "basal cell carcinoma thumb." The authors identified 176 cases of dorsal hand BCCs in the literature, 120 of which had sufficient data for analysis. Only 4 cases were treated with Mohs micrographic surgery (MMS). The authors present 14 additional cases of dorsal hand BCCs treated with MMS. Basal cell carcinomas on the dorsal hand occur infrequently, and potential risk factors include being a male of white descent and personal history of skin cancer. Mohs micrographic surgery seems to be an effective treatment method.

  7. Basal Cell Carcinoma of the Dorsal Foot: An Update and Comprehensive Review of the Literature.

    Science.gov (United States)

    Loh, Tiffany Y; Rubin, Ashley G; Jiang, Shang I Brian

    2017-01-01

    Ultraviolet radiation is a well-known risk factor for basal cell carcinoma (BCC). Therefore, the high incidence of BCCs in sun-exposed areas such as the head and neck is unsurprising. However, unexpectedly, BCCs on the sun-protected dorsal foot have also been reported, and tumor occurrence here suggests that other factors besides ultraviolet radiation may play a role in BCC pathogenesis. Because only few dorsal foot BCCs have been reported, data on their clinical features and management are limited. To perform an updated review of the literature on clinical characteristics and treatment of dorsal foot BCCs. We conducted a comprehensive literature review by searching the PubMed database with the key phrases "basal cell carcinoma dorsal foot," "basal cell carcinoma foot," and "basal cell carcinoma toe." We identified 20 cases of dorsal foot BCCs in the literature, 17 of which had sufficient data for analysis. Only 1 case was treated with Mohs micrographic surgery. We present 8 additional cases of dorsal foot BCCs treated with Mohs micrographic surgery. Basal cell carcinomas on the dorsal foot are rare, and potential risk factors include Caucasian descent and personal history of skin cancer. Mohs micrographic surgery seems to be an effective treatment option.

  8. Responses of spinal dorsal horn neurons to foot movements in rats with a sprained ankle

    Science.gov (United States)

    Kim, Jae Hyo; Kim, Hee Young; Chung, Kyungsoon

    2011-01-01

    Acute ankle injuries are common problems and often lead to persistent pain. To investigate the underlying mechanism of ankle sprain pain, the response properties of spinal dorsal horn neurons were examined after ankle sprain. Acute ankle sprain was induced manually by overextending the ankle of a rat hindlimb in a direction of plantarflexion and inversion. The weight-bearing ratio (WBR) of the affected foot was used as an indicator of pain. Single unit activities of dorsal horn neurons in response to plantarflexion and inversion of the foot or ankle compression were recorded from the medial part of the deep dorsal horn, laminae IV-VI, in normal and ankle-sprained rats. One day after ankle sprain, rats showed significantly reduced WBRs on the affected foot, and this reduction was partially restored by systemic morphine. The majority of deep dorsal horn neurons responded to a single ankle stimulus modality. After ankle sprain, the mean evoked response rates were significantly increased, and afterdischarges were developed in recorded dorsal horn neurons. The ankle sprain-induced enhanced evoked responses were significantly reduced by morphine, which was reversed by naltrexone. The data indicate that movement-specific dorsal horn neuron responses were enhanced after ankle sprain in a morphine-dependent manner, thus suggesting that hyperactivity of dorsal horn neurons is an underlying mechanism of pain after ankle sprain. PMID:21389306

  9. Prevalencia del juanete de sastre y quinto dedo adducto varo en el baile flamenco profesional. Prevalence of tailor's bunion and fifth toe adductus varus in professional flamenco dancing.

    Directory of Open Access Journals (Sweden)

    Nadia Salti

    2013-05-01

    Full Text Available El Juanete de Sastre es una deformidad adquirida que afecta al quinto metatarsiano y quinto dedo del pie. Se caracteriza por una prominencia lateral en la cabeza del quinto metatarsiano, con una marcada desviación medial del quinto dedo y una desviación lateral del V metatarsiano. De origen multifactorial, hablamos de una etiología micro traumática influida por posturas viciosas en dinámica, estática o sedente, por la influencia del calzado y la presencia de alteraciones biomecánicas de la extremidad inferior y pies; aunque coexisten otros factores predisponentes. Mediante un estudio observacional transversal, realizado en diferentes academias de flamenco de Andalucía, el Área Clínica de Podología de la Universidad de Sevilla y centros privados de Investigación y Podología, sobre 27 participantes (40 pies de bailaoras y 14 pies de bailaores profesionales de flamenco, se determinó que existe una prevalencia del 14.8% de Juanetes de Sastre y del 35% de quintos dedos adducto varo. En ambos casos, la prevalencia es mayor entre la población femenina. Los años de actividad (años practicando baile flamenco influyen significativamente en la aparición de estas deformidades.The tailor’s bunion is an acquired deformity that concerns the fifth metatarsal and the fifth toe. It is defined by a lateral protuberance in the fifth metatarsal head with the fifth toe medial curvature and fifth metatarsal lateral curvature. Its origin can be derived from multiple factors as micro traumatic etiology influenced by repetitive positions in dynamics, static and sitting, shoewear´s influence and biomechanics alterations in the lower extremity and feet, although other influence factors are also found. By means of a cross-sectional and observational study carried out in different Andalusia flamenco dance academies, Podiatry Clinic of the University of Seville and podiatry’s private research centers, in 27 participants (40 women flamenco dancers´ feet

  10. Primary afferent terminal sprouting after a cervical dorsal rootlet section in the macaque monkey.

    Science.gov (United States)

    Darian-Smith, Corinna

    2004-03-01

    We examined the role of primary afferent neurons in the somatosensory cortical "reactivation" that occurs after a localized cervical dorsal root lesion (Darian-Smith and Brown [2000] Nat. Neurosci. 3:476-481). After section of the dorsal rootlets that enervate the macaque's thumb and index finger (segments C6-C8), the cortical representation of these digits was initially silenced but then re-emerged for these same digits over 2-4 postlesion months. Cortical reactivation was accompanied by the emergence of physiologically detectable input from these same digits within dorsal rootlets bordering the lesion site. We investigated whether central axonal sprouting of primary afferents spared by the rhizotomy could mediate this cortical reactivation. The cortical representation of the hand was mapped electrophysiologically 15-25 weeks after the dorsal rootlet section to define this reactivation. Cholera toxin subunit B conjugated to horseradish peroxidase was then injected into the thumb and index finger pads bilaterally to label the central terminals of any neurons that innervated these digits. Primary afferent terminal proliferation was assessed in the spinal dorsal horn and cuneate nucleus at 7 days and 15-25 postlesion weeks. Labeled terminal bouton distributions were reconstructed and the "lesion" and control sides compared within each monkey. Distributions were significantly larger on the side of the lesion in the dorsal horn and cuneate nucleus at 15-25 weeks after the dorsal rootlet section, than those mapped only 7 days postlesion. Our results provide direct evidence for localized sprouting of spared (uninjured) primary afferent terminals in the dorsal horn and cuneate nucleus after a restricted dorsal root injury. Copyright 2004 Wiley-Liss, Inc.

  11. R and D status and requirements for PIE in the fields of the HTGR fuel and the innovative basic research on High-Temperature Engineering

    Energy Technology Data Exchange (ETDEWEB)

    Sawa, Kazuhiro; Tobita, Tsutomu; Sumita, Junya [Japan Atomic Energy Research Inst., Oarai, Ibaraki (Japan). Oarai Research Establishment; Ishihara, Masahiro; Hayashi, Kimio; Hoshiya, Taiji; Sekino, Hajime; Ooeda, Etsurou

    1999-09-01

    The High Temperature Engineering Test Reactor (HTTR), which is the first high temperature gas-cooled reactor (HTGR) in Japan, achieved its first criticality in November 1998 at the Oarai Research Establishment of the Japan Atomic Energy Research Institute (JAERI). In the field of HTGR fuel development, JAERI will proceed research and development (R and D) works by the following steps: (STEP-1) confirmation of irradiation performance of the first-loading fuel of the HTTR, (STEP-2) study on irradiation performance of high burnup SiC-coated fuel particle and (STEP-3) development of ZrC-coated fuel particle. Requirements for post-irradiation examination (PIE) are different for each R and D step. In STEP-1, firstly, hot cells will be prepared in the HTTR reactor building to handle spent fuels. In parallel, general equipments such as those for deconsolidation of fuel compacts and for handling coated fuel particles will be installed in the Hot Laboratory at Oarai. In STEP-2, precise PIE techniques, for example, Raman spectroscopy for measurement of stress on irradiated SiC layer, will be investigated. In STEP-3, new PIE techniques should be developed to investigate irradiation behavior of ZrC-coated particle. In the field of the innovative basic research on high-temperature engineering, some preliminary tests have been made on the research areas of (1) new materials development, (2) fusion technology, (3) radiation chemistry and (4) high-temperature in-core instrumentation. Requirements for PIE are under investigation, in particular in the field of the new materials development. Besides more general apparatuses including transmission electron microscopy (TEM), some special apparatuses such as an electron spin resonance (ESR) spectrometer, a specific resistance/Hall coefficient measuring system and a differential scanning calorimeter (DSC) are planned to install in the Hot Laboratory at Oarai. Acquisition of advanced knowledge on the irradiation behavior is expected in

  12. Persistent dorsal ophthalmic artery arising from the internal carotid artery: Report of three cases

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Jae Hwan; Lee, Ghi Jai; Shim, Jae Chan; Lee, Kyoung Eun; Kim, Ho Kyun; Suh, Jung Ho [Dept. of Radiology, Seoul Paik Hospital, Inje University College of Medicine, Seoul (Korea, Republic of)

    2016-12-15

    Normally, the ophthalmic artery (OA) arises from the supraclinoid segment of the internal carotid artery (ICA) and enters the orbit via the optic canal. A persistent dorsal OA is a rare variation that originates from the cavernous segment of the ICA and enters the orbit via the superior orbital fissure. To the best of our knowledge, persistent dorsal OA has not been described in the Korean literature. In this paper, we report three cases of persistent dorsal OA with review of the literature on embryogenesis and other origins of the OA.

  13. Effect of dorsal hippocampal lesion compared to dorsal hippocampal blockade by atropine on reference memory in vision deprived rats.

    Science.gov (United States)

    Dhume, R A; Noronha, A; Nagwekar, M D; Mascarenhas, J F

    1989-10-01

    In order to study the primacy of the hippocampus in place learning function 24 male adult albino rats were hippocampally-lesioned in dorsal hippocampus involving fornical damage (group I); sham operated for comparison with group I (group II); cannulated for instillation of atropine sulphate in the same loci as group I (group III); and cannulated for instillation of saline which served as control for group III (group IV). All the animals were enucleated and their reference memory (long-term memory) was tested, using open 4-arm radial maze. There was loss of reference memory in groups I and III. However, hippocampally-lesioned animals, showed recovery of reference memory deficit within a short period of 10 days or so. Whereas atropinized animals showed persistent reference memory deficit as long as the instillation effect continued. The mechanism involved in the recovery of reference memory in hippocampally-lesioned animals and persistent deficit of reference memory in atropinized animals has been postulated to explain the primacy of hippocampus in the place learning function under normal conditions.

  14. Profil bactériologique du pied diabétique et son impact sur le choix des antibiotiques

    Science.gov (United States)

    Zemmouri, Adil; Tarchouli, Mohamed; Benbouha, Abdellatif; Lamkinsi, Tarik; Bensghir, Mustapha; Elouennass, Mostafa; Haimeur, Cherqui

    2015-01-01

    Introduction Analyse du profil bactériologique des pieds diabétiques pris en charge à l'hôpital militaire de Rabat et son influence sur l'antibiothérapie de première intention. Méthodes Etude prospective non randomisée étalée sur 18 mois, ayant concerné 105 patients. Après recueil des données et en attente des résultats bactériologiques nos patients ont été divisés en deux groupes: un groupe a été mis sous Amoxicilline + Acide clavulanique + Gentamycine (59 patients) et un groupe sous Ertapénème±Gentamycine (46 patients). Résultats L’étude a regroupé 85 hommes et 20 femmes (sexe ratio = 4.26). L’âge moyen est de 64.4 ans. La gangrène a été observée chez 79% des malades; elle était humide-donc surinfectée en principe- dans 43% des cas. Par ailleurs, 67% des malades ont un chiffre de globules blancs 12000 définissant une infection sévère. L'ostéolyse a été mise en évidence chez 27% de nos patients. Parmi les différentes techniques de prélèvements: 81% ont été profonds dont 21% de biopsie osseuse per opératoire et 14% de prélèvements combinés. 42% de ces prélèvements sont poly microbiens et 21% sont stériles. Les résultats bactériologiques viennent confirmer la prédominance des bactéries aérobies à Gram positif. Le taux de remplacement de l'Ertapénème est de 22% contre un taux de 50% pour l'Amoxiclav. Conclusion L'antibiothérapie ne doit être instaurée qu'en cas d'infection du pied diabétique diagnostiquée sur les critères cliniques établis par les consensus internationaux récents. Le respect des mesures de lutte contre la diffusion de la résistance bactérienne s'avère primordiale. PMID:27386024

  15. Long-term outcomes five years after selective dorsal rhizotomy

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    Lagergren Jan

    2008-12-01

    Full Text Available Abstract Background Selective dorsal rhizotomy (SDR is a well accepted neurosurgical procedure performed for the relief of spasticity interfering with motor function in children with spastic cerebral palsy (CP. The goal is to improve function, but long-term outcome studies are rare. The aims of this study were to evaluate long-term functional outcomes, safety and side effects during five postoperative years in all children with diplegia undergoing SDR combined with physiotherapy. Methods This study group consisted of 35 children, consecutively operated, with spastic diplegia, of which 26 were Gross Motor Function Classification System (GMFCS levels III–V. Mean age was 4.5 years (range 2.5–6.6. They were all assessed by the same multidisciplinary team at pre- and at 6, 12, 18 months, 3 and 5 years postoperatively. Clinical and demographic data, complications and number of rootlets cut were prospectively registered. Deep tendon reflexes and muscle tone were examined, the latter graded with the modified Ashworth scale. Passive range of motion (PROM was measured with a goniometer. Motor function was classified according to the GMFCS and measured with the Gross Motor Function Measure (GMFM-88 and derived into GMFM-66. Parent's opinions about the children's performance of skills and activities and the amount of caregiver assistance were measured with Pediatric Evaluation Disability Inventory (PEDI. Results The mean proportion of rootlets cut in S2-L2 was 40%. Muscle tone was immediately reduced in adductors, hamstrings and dorsiflexors (p Conclusion SDR is a safe and effective method for reducing spasticity permanently without major negative side effects. In combination with physiotherapy, in a group of carefully selected and systematically followed young children with spastic diplegia, it provides lasting functional benefits over a period of at least five years postoperatively.

  16. Neurochemical characterization of the tree shrew dorsal striatum

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    MATTHEW W RICE

    2011-08-01

    Full Text Available The striatum is a major component of the basal ganglia and is associated with motor and cognitive functions. Striatal pathologies have been linked to several disorders, including Huntington's, Tourette's syndrome, obsessive-compulsive disorders and schizophrenia. For the study of these striatal pathologies different animal models have been used, including rodents and non-human primates. Rodents lack on morphological complexity (for example, the lack of well defined caudate and putamen nuclei, which makes it difficult to translate data to the human paradigm. Primates, and especially higher primates, are the closest model to humans, but there are ever-increasing restrictions to the use of these animals for research. In our search for a non-primate animal model with a striatum that anatomically (and perhaps functionally can resemble that of humans, we turned our attention to the tree shrew. Evolutionary genetic studies have provided strong data supporting that the tree shrews (Scadentia are one of the closest groups to primates, although their brain anatomy has only been studied in detail for specific brain areas. Morphologically, the tree shrew striatum resembles the primate striatum with the presence of an internal capsule separating the caudate and putamen, but little is known about its neurochemical composition. Here we analyzed the expression of calcium-binding proteins, the presence and distribution of the striosome and matrix compartments (by the use of calbindin, tyrosine hydroxylase and acetylcholinesterase immunohistochemistry, and the GABAergic system by immunohistochemistry against glutamic acid decarboxylase and Golgi impregnation. In summary, our results show that when compared to primates, the tree shrew dorsal striatum presents striking similarities in the distribution of most of the markers studied, while presenting some marked divergences when compared to the rodent striatum.

  17. Dorsal hippocampus is necessary for visual categorization in rats.

    Science.gov (United States)

    Kim, Jangjin; Castro, Leyre; Wasserman, Edward A; Freeman, John H

    2018-02-23

    The hippocampus may play a role in categorization because of the need to differentiate stimulus categories (pattern separation) and to recognize category membership of stimuli from partial information (pattern completion). We hypothesized that the hippocampus would be more crucial for categorization of low-density (few relevant features) stimuli-due to the higher demand on pattern separation and pattern completion-than for categorization of high-density (many relevant features) stimuli. Using a touchscreen apparatus, rats were trained to categorize multiple abstract stimuli into two different categories. Each stimulus was a pentagonal configuration of five visual features; some of the visual features were relevant for defining the category whereas others were irrelevant. Two groups of rats were trained with either a high (dense, n = 8) or low (sparse, n = 8) number of category-relevant features. Upon reaching criterion discrimination (≥75% correct, on 2 consecutive days), bilateral cannulas were implanted in the dorsal hippocampus. The rats were then given either vehicle or muscimol infusions into the hippocampus just prior to various testing sessions. They were tested with: the previously trained stimuli (trained), novel stimuli involving new irrelevant features (novel), stimuli involving relocated features (relocation), and a single relevant feature (singleton). In training, the dense group reached criterion faster than the sparse group, indicating that the sparse task was more difficult than the dense task. In testing, accuracy of both groups was equally high for trained and novel stimuli. However, both groups showed impaired accuracy in the relocation and singleton conditions, with a greater deficit in the sparse group. The testing data indicate that rats encode both the relevant features and the spatial locations of the features. Hippocampal inactivation impaired visual categorization regardless of the density of the category-relevant features for

  18. Potencial del Agua del suelo

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    Bustamante Heliodoro

    1986-12-01

    Full Text Available La energía potencial del agua presenta diferencias de un punto del suelo a otro; esas diferencias son las que originan el movimiento del agua de acuerdo a la tendencia universal de la materia en el sentido de moverse de donde la energía potencial es mayor a donde dicha energía es menor. En el suelo el agua en consecuencia se mueve hacia donde su energía decrece hasta lograr su estado de equilibrio. Se desprende entonces que la cantidad de energía potencial absoluta contenida en el agua, no es importante por sí misma, sino por su relación con la energía en diferentes lugares dentro del suelo. El concepto Potencial de agua del suelo es un criterio para esta energía.

  19. El "Gallinazo" En La Escuela. Violencia Domestica Y Construcción Social De La Masculinidad Al Pie Del Páramo De Sumapaz, Colombia.

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    Santiago Álvarez.

    2010-06-01

    Full Text Available This text analyses the relations between domestic violence and ideas and practices that produce the social construction of what a peasant man has to be in a town at the foot of the Paramo of Sumapaz in the Colombian Andes. Observing the male behaviour, the author describes how violence, aggression, the hard work of the land, alcohol, the control of home and extramarital adventures expressed force and power that is transforms in respect. In this fashion, the rich and mature peasant is considered a powerful man and respected as such. In contrast, the young poor peasant, you have to be excessively aggressive because he is obliged to show his might in order to be considered and respected socially. In a community where the power relations are unstable and fluid, violence is used to construct a self. Aggression and competition are central elements in the social construction of masculinity. In spite of this, the aggressive actions against women and children are not perceived as violence but as Internal problems of any couple or family. In fact, when women protest for the beatings they do it internally and do not put these matters in the legal system. In this way, the author show as to difficulty: the perception of to behaviour is seen in a different way by the observed and by the researcher. These behaviours are not stigmatised by actors, find that the other strategies to deal with violent actions.

  20. TIEMPOS Y RENDIMIENTOS DEL ASERRÍO EN LA REGIÓN DE EL SALTO, DURANGO, MÉXICO

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    Juan Abel Nájera-Luna

    2011-01-01

    rendimiento en madera aserrada del 57.5 % sin corteza y 52.17 % con corteza. El tiempo promedio para aserrar 1,000 pies tablares se estimó en 25.09 minutos. La productividad fue de 7.57 m3.h-1 y la velocidad de alimentación de 46.47 m.min-1. Se encontró que el rendimiento en madera aserrada es afectado por el diámetro, largo y conicidad de las trozas.

  1. Libertad de expresión y beligerancia mediática: tres diarios venezolanos en pie de guerra

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    Lic. Sebastián de la Nuez A.

    2002-01-01

    Full Text Available En Venezuela, dentro del marco de conflictividad que ha signado la relación medios-gobierno en los últimos tres años, se ha venido discutiendo lo que podría denominarse La agenda sobre libertad de expresión. Dentro de esta agenda hay varios bloques noticiosos. Su seguimiento a través de tres diarios de circulación nacional constituye la esencia de este trabajo de análisis. Se derivan interesantes conclusiones acerca del tratamiento mediático de esta Agenda y, por ende, del comportamiento de estos periódicos en situación de conflicto abierto con el gobierno de Hugo Chávez.

  2. Agenesis of dorsal pancreas with eventration of diaphragm and intrapancreatic pseudocyst: a rare entity

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    Poras Chaudhary

    2013-02-01

    Full Text Available A case of acute pancreatitis in a 43-year-old male patient, which was eventually diagnosed as agenesis of dorsal pancreas with eventration of left hemidiaphragm and intrapancreatic pseudocyst is being reported.

  3. Transcallosal connection patterns of opposite dorsal premotor regions support a lateralized specialization for action and perception

    NARCIS (Netherlands)

    van der Hoorn, Anouk; Potgieser, Adriaan R. E.; de Jong, Bauke M.

    Lateralization of higher brain functions requires that a dominant hemisphere collects relevant information from both sides. The right dorsal premotor cortex (PMd), particularly implicated in visuomotor transformations, was hypothesized to be optimally located to converge visuospatial information

  4. Calcium activity of upper thoracic dorsal root ganglion neurons in zucker diabetic Fatty rats

    DEFF Research Database (Denmark)

    Ghorbani, Marie Louise; Nyborg, Niels C B; Fjalland, Bjarne

    2013-01-01

    The aim of the present study was to examine the calcium activity of C8-T5 dorsal root ganglion (DRG) neurons from Zucker diabetic fatty rats. In total, 8 diabetic ZDF fatty animals and 8 age-matched control ZDF lean rats were employed in the study. C8-T5 dorsal root ganglia were isolated bilatera......The aim of the present study was to examine the calcium activity of C8-T5 dorsal root ganglion (DRG) neurons from Zucker diabetic fatty rats. In total, 8 diabetic ZDF fatty animals and 8 age-matched control ZDF lean rats were employed in the study. C8-T5 dorsal root ganglia were isolated...... in calcium activity of the DRG neurons were found, potentially indicating altered neuronal responses during myocardial ischemia....

  5. Human dorsal striatum encodes prediction errors during observational learning of instrumental actions.

    Science.gov (United States)

    Cooper, Jeffrey C; Dunne, Simon; Furey, Teresa; O'Doherty, John P

    2012-01-01

    The dorsal striatum plays a key role in the learning and expression of instrumental reward associations that are acquired through direct experience. However, not all learning about instrumental actions require direct experience. Instead, humans and other animals are also capable of acquiring instrumental actions by observing the experiences of others. In this study, we investigated the extent to which human dorsal striatum is involved in observational as well as experiential instrumental reward learning. Human participants were scanned with fMRI while they observed a confederate over a live video performing an instrumental conditioning task to obtain liquid juice rewards. Participants also performed a similar instrumental task for their own rewards. Using a computational model-based analysis, we found reward prediction errors in the dorsal striatum not only during the experiential learning condition but also during observational learning. These results suggest a key role for the dorsal striatum in learning instrumental associations, even when those associations are acquired purely by observing others.

  6. The dorsal thoracic fascia: anatomic significance with clinical applications in reconstructive microsurgery.

    Science.gov (United States)

    Kim, P S; Gottlieb, J R; Harris, G D; Nagle, D J; Lewis, V L

    1987-01-01

    The anatomic distribution and potential arterial flow patterns of the circumflex scapular artery were investigated by Microfil injection. These studies demonstrated that the circumflex scapular artery lies within the dorsal thoracic fascia, which plays a significant role in the circulation of the overlying skin and subcutaneous tissue. We conclude that scapular/parascapular flaps are fasciocutaneous flaps, the dorsal thoracic fascia can be transferred as a free flap without its overlying skin and subcutaneous tissue, and intercommunication exists between the myocutaneous perforators of the latissimus dorsi myocutaneous flap and the vascular plexus of the dorsal thoracic fascia. We present microvascular cases in which the vascular properties of the dorsal thoracic fascia facilitated wound closure with free fascia flaps or expanded cutaneous or myocutaneous flaps.

  7. EFECTO DE LA COMPOSICIÓN DEL GAS DE REFINERÍA SOBRE LAS CARACTERÍSTICAS DEL PROCESO DE COMBUSTIÓN

    Directory of Open Access Journals (Sweden)

    O. M. Cala

    2013-12-01

    Full Text Available En este artículo de investigación científica se analiza el efecto del cambio de la composición del gas combustible (Gas de Refinería (GR por Gas Natural (GN sobre las características del proceso combustión en hornos de la industria de refinación del petróleo; se evaluó el poder calorífico, el índice de Wobbe (IW y exceso de oxígeno, para mezclas combustibles de composición variable. Mediante simulación computacional del proceso de combustión se calculó la temperatura adiabática de llama, eficiencia y la composición de los productos de combustión. Se evaluaron mezclas de gases combustibles con poderes caloríficos entre 800-2500 Btu/pie3 y se compararon con la combustión de gas natural. Se registró variabilidad en la temperatura adiabática y la eficiencia en función de la composición del gas y el exceso de oxígeno, lo que genera inestabilidad en el horno y mayor impacto ambiental.

  8. Responses of spinal dorsal horn neurons to foot movements in rats with a sprained ankle

    OpenAIRE

    Kim, Jae Hyo; Kim, Hee Young; Chung, Kyungsoon; Chung, Jin Mo

    2011-01-01

    Acute ankle injuries are common problems and often lead to persistent pain. To investigate the underlying mechanism of ankle sprain pain, the response properties of spinal dorsal horn neurons were examined after ankle sprain. Acute ankle sprain was induced manually by overextending the ankle of a rat hindlimb in a direction of plantarflexion and inversion. The weight-bearing ratio (WBR) of the affected foot was used as an indicator of pain. Single unit activities of dorsal horn neurons in res...

  9. Dorsal buccal mucosal graft urethroplasty for anterior urethral stricture by Asopa technique.

    Science.gov (United States)

    Pisapati, V L N Murthy; Paturi, Srimannarayana; Bethu, Suresh; Jada, Srikanth; Chilumu, Ramreddy; Devraj, Rahul; Reddy, Bhargava; Sriramoju, Vidyasagar

    2009-07-01

    Buccal mucosal graft (BMG) substitution urethroplasty has become popular in the management of intractable anterior urethral strictures with good results. Excellent long-term results have been reported by both dorsal and ventral onlay techniques. Asopa reported a successful technique for dorsal placement of BMG in long anterior urethral strictures through a ventral sagittal approach. To evaluate prospectively the results and advantages of dorsal BMG urethroplasty for recurrent anterior urethral strictures by a ventral sagittal urethrotomy approach (Asopa technique). From December 2002 to December 2007, a total of 58 men underwent dorsal BMG urethroplasty by a ventral sagittal urethrotomy approach for recurrent urethral strictures. Forty-five of these patients with a follow-up period of 12-60 mo were prospectively evaluated, and the results were analysed. The urethra was split twice at the site of the stricture both ventrally and dorsally without mobilising it from its bed, and the buccal mucosal graft was secured in the dorsal urethral defect. The urethra was then retubularised in one stage. The overall results were good (87%), with a mean follow-up period of 42 mo. Seven patients developed minor wound infection, and five patients developed fistulae. There were six recurrences (6:45, 13%) during the follow-up period of 12-60 mo. Two patients with a panurethral stricture and four with bulbar or penobulbar strictures developed recurrences and were managed by optical urethrotomy and self-dilatation. The medium-term results were as good as those reported with the dorsal urethrotomy approach. Long-term results from this and other series are awaited. More randomised trials and meta-analyses are needed to establish this technique as a procedure of choice in future. The ventral sagittal urethrotomy approach is easier to perform than the dorsal urethrotomy approach, has good results, and is especially useful in long anterior urethral strictures.

  10. Thermal effects of dorsal head immersion in cold water on nonshivering humans.

    Science.gov (United States)

    Giesbrecht, Gordon G; Lockhart, Tamara L; Bristow, Gerald K; Steinman, Allan M

    2005-11-01

    Personal floatation devices maintain either a semirecumbent flotation posture with the head and upper chest out of the water or a horizontal flotation posture with the dorsal head and whole body immersed. The contribution of dorsal head and upper chest immersion to core cooling in cold water was isolated when the confounding effect of shivering heat production was inhibited with meperidine (Demerol, 2.5 mg/kg). Six male volunteers were immersed four times for up to 60 min, or until esophageal temperature = 34 degrees C. An insulated hoodless dry suit or two different personal floatation devices were used to create four conditions: 1) body insulated, head out; 2) body insulated, dorsal head immersed; 3) body exposed, head (and upper chest) out; and 4) body exposed, dorsal head (and upper chest) immersed. When the body was insulated, dorsal head immersion did not affect core cooling rate (1.1 degrees C/h) compared with head-out conditions (0.7 degrees C/h). When the body was exposed, however, the rate of core cooling increased by 40% from 3.6 degrees C/h with the head out to 5.0 degrees C/h with the dorsal head and upper chest immersed (P immersed (approximately 10%). The exaggerated core cooling during dorsal head immersion (40% increase) may result from the extra heat loss affecting a smaller thermal core due to intense thermal stimulation of the body and head and resultant peripheral vasoconstriction. Dorsal head and upper chest immersion in cold water increases the rate of core cooling and decreases potential survival time.

  11. SCANNING ELECTRON MICROSCOPY STUDY OF THE DORSAL SURFACE OF THE TONGUE IN Chaetophractus vellerosus (MAMMALIA, DASYPODIDAE)

    OpenAIRE

    Estecondo, Silvia; Codón, Stella Maris; Casanave, Emma Beatriz

    2001-01-01

    The characteristics of the dorsal surface of Chaetophractus vellerosus tongue were studied by scanning electron microscopy. Simple or branched filiform, fungiform and vallate papillae are described. Simple conical filiform papillae appear in the apex, lateral edges and posterior third, caudally to the circumvallated ones. The branched papillae are densely distributed all over the dorsal surface of the lingual body. Fungiform ones are scattered among the branched filiform papillae. In the post...

  12. Propagation of a dorsal cortical fracture of the third metacarpal bone in two horses

    International Nuclear Information System (INIS)

    Spurlock, G.H.

    1988-01-01

    Seemingly, propagation of a dorsal cortical fracture in the third metacarpal bone developed after continued race performance in 2 horses. Historically, both horses had intermittent lameness that had responded to nonsteroidal anti-inflammatory drugs and brief rest periods. However, lameness in both horses had increased in severity. Radiography revealed a dorsal cortical fracture of the third metacarpal bone, with propagation of the fracture plane proximally. Fractures were incomplete and healed with stall rest in both horses

  13. Heterotaxy syndrome with associated agenesis of dorsal pancreas and polysplenia: A case report

    Directory of Open Access Journals (Sweden)

    Syed Althaf Ali1

    2015-01-01

    Full Text Available Heterotaxy syndrome is a rare embryological disorder comprising of polysplenia, partial agenesis of dorsal pancreas, malrotation of gut, cardiac and vascular anomalies resulting from failure of development of the usual left–right asymmetry of organs. We report a rare case of heterotaxy syndrome with polysplenia, partial agenesis of dorsal pancreas and malrotation of gut in a 28 year female presenting with subacute intestinal obstruction along with imaging illustrations, brief discussion and thorough review of literature.

  14. [Application of pie-crusting the medial collateral ligament release in arthroscopic surgery for posterior horn of 
medial meniscus in knee joint].

    Science.gov (United States)

    Zhu, Weihong; Tang, Qi; Liao, Lele; Li, Ding; Yang, Yang; Chen, You

    2017-09-28

    To explore the effectiveness and safety of pie-crusting the medial collateral ligament release (MCL) in treating posterior horn of medial meniscus (PHMM) tear in tight medial tibiofemoral compartment of knee joint.
 Methods: Thirty-two consecutive patients with PHMM tear in tight medial tibiofemoral compartment of knee joint were admitted to our department from January, 2013 to December, 2014. All patients were performed pie-crusting the MCL release at its tibial insertion with 18-gauge intravenous needle. All patients were evaluated by valgus stress test and bilateral valgus stress radiograph at postoperative 1st day, 4th week and 12th week. Visual Analogue Scales (VAS), Lysholm scores, Tegner scores and International Knee Documentation Committee (IKDC) scores were recorded at the 1st, 3th, 6th month follow-up, then follow-up every 6 months.
 Results: The mean follow-up was 28 (24-36) months. All cases were negative in valgus stress test. MCL rupture, femoral fracture, articular cartilage lesion and neurovascular injury were not found at the last follow-up. The median medial joint space width of affected side and unaffected side for valgus stress radiographs were 6.8 mm and 4.3 mm (P0.05) at the 12th week, respectively. VAS scores was changed from 4.5±1.5 preoperatively to 1.7±1.0 at the final follow-up (t=16.561, Pjoint.

  15. Lead exposure and biological effects in pied flycatchers (Ficedula hypoleuca) before and after the closure of a lead mine in northern Sweden

    International Nuclear Information System (INIS)

    Berglund, A.M.M.; Ingvarsson, P.K.; Danielsson, H.; Nyholm, N.E.I.

    2010-01-01

    Mining activities affect the surrounding environment by increasing exposure to metals. In this study, metal accumulation and its effects on reproduction and health of pied flycatcher (Ficedula hypoleuca) nestlings were monitored before and up to five years after a lead mine and enrichment plant closed down. The lead concentration in moss, nestling blood, liver and feces all indicated decreased lead exposure by at least 31% after closure, although only blood lead decreased significantly. Although the birds responded fairly well to the changed atmospheric deposition (based on moss samples), concentrations were still higher compared with birds in a reference area, and breeding was affected at the mine (smaller clutches and higher mortality). Surviving nestlings suffered from lower hemoglobin levels, mean cell hemoglobin concentrations and inhibited δ-aminolevulinic acid dehydratase activity. Lead poisoning contributed to poor health and adverse reproductive effects, but other factors (e.g. increased parasitic load) probably also affected the birds. - Increased mortality and lower blood values in pied flycatcher (Ficedula hypoleuca) nestlings near a closed lead mine.

  16. LOCA testing of high burnup PWR fuel in the HBWR. Additional PIE on the cladding of the segment 650-5

    Energy Technology Data Exchange (ETDEWEB)

    Oberlaender, B.C.; Espeland, M.; Jenssen, H.K.

    2008-07-01

    IFA-650.5, a test with pre-irradiated fuel in the Halden Project LOCA test series, was conducted on October 23rd, 2006. The fuel rod had been used in a commercial PWR and had a high burnup, 83 MWd/kgU. Experimental arrangements of the fifth test were similar to the preceding LOCA tests. The peak cladding temperature (PCT) level was higher than in the third and fourth tests, 1050 C. A peak temperature close to the target was achieved and cladding burst occurred at approx. 750 C. Within the joint programme framework of the Halden Project PIE was done, consisting of gamma scanning, visual inspection, neutron-radiography, hydrogen analysis and metallography / ceramography. An additional extensive PIE including metallography, hydrogen analysis, and hardness measurements of cross-sections at seven axial elevations was done. It was completed to study the high burnup and LOCA induced effects on the Zr-4 cladding, namely the migration of oxygen into the cladding from the inside surface, the cladding distension, and the burst (author)(tk)

  17. Associations of leisure-time physical activity with balance and lower extremity strength: a validation of the neuromuscular part of the Physical Activity Pie.

    Science.gov (United States)

    Lindström, Paula J; Suni, Jaana H; Nygård, Clas-Håkan

    2009-07-01

    The importance of neuromuscular-type exercise (NME) has been recognized in recent recommendations for public health. However, the knowledge on associations and dose response of different types of leisure-time physical activity (LTPA) with musculoskeletal fitness and health is incomplete. This study evaluated the validity of the NME recommendation for public health introduced by the Physical Activity Pie. Engagement in LTPA and health-related fitness were assessed in 2 consecutive studies with the same adult population age 30 to 69 years (n = 575). Cross-sectional associations between different LTPA types and motor and musculoskeletal fitness were examined by logistic-regression models. Engagement in NME was associated with good static and dynamic balance and lower extremity strength. The highest odds ratios (OR) were found between brisk NME and static balance (most vs least fit OR = 2.39, moderate vs least fit OR = 1.94) and brisk NME and leg strength (more vs least fit OR = 2.10). Some associations were also found between brisk aerobic exercise and good balance. This cross-sectional study suggests that the recommendation for NME in the Physical Activity Pie is valid in terms of balance and leg strength, the 2 major fitness factors related to mobility functioning, especially among aging adults.

  18. Ana?lisis cinemático de la marcha en pacientes con pie zambo tratados mediante el me?todo de Ponseti frente a la te?cnica quiru?rgica de liberacio?n posterior

    OpenAIRE

    Ferrando, A.; Salom Taverner, M.; Page, A.

    2018-01-01

    El objetivo principal de este proyecto consiste en valorar la evolución de la marcha en niños en edad preadolescente tratados mediante el método de Ponseti frente a los tratados mediante liberación posterior a partir de técnicas de valoración de la marcha mediante análisis biomecánico. Material y Métodos Estudio retrospectivo de casos y controles aprobado por el comité de ética. Grupo 1: 28 niños (39 pies) tratados mediante liberación posterior. Grupo 2: 18 pacientes (31 pies) tratados median...

  19. The YouTube Project: “The PewDiePie versus The Wall Street Journal Scandal – an in-depth analysis of PewDiePie’s online audience”

    OpenAIRE

    Jensen, Natalie Madeleine; Rasmussen, Anna Melanie Bæckmann; Cillo, Dominic

    2017-01-01

    In this dissertation, the aim is to investigate the multi-faceted events and belonging themes within The PewDiePie versus The Wall Street Journal Scandal – henceforth described as The PewDiePie Scandal. Here, the main goal within this dissertation is to answer questions in regards to PewDiePie’s online audience, how they perceive him and the relationship between the YouTuber and the viewership. Furthermore, the investigation will delve into matters of the major support provided by his audienc...

  20. Periostite metacarpiana dorsal: incidência e fatores pré-disponentes

    Directory of Open Access Journals (Sweden)

    Flávio Gomes de Oliveira

    2006-04-01

    Full Text Available Forty two 2-year-old thoroughbreds were examined clinically at intervals of 15 days during their training for the first race to determine the incidence and the predisposing factors of dorsal metacarpal disease. During the first year 25 horses were followed during 2 months and in the second year the follow up was done for 4 months in 17 . Horses' data like gender, average speed, speed exercise work and trainer were also collected. Dorsal metacarpal disease was diagnosed in 28% and 70,6% of the 2 year-old thoroughbreds in the first and second year of the study, respectively. Total incidence was 45%. The incidence and average speed was not affected by gender. The average speed achieved by affected and none affected horses remained between 16 and 18m/s. On 500 and 700m speed exercise, the average speed of affected horses was higher than of none affected ones (p<0,05. Ten out of 19 horses showed dorsal metacarpal disease signs at the distance of 700m. There was significant difference between trainers regarding the incidence of dorsal metacarpal disease and average speed of their horses. 2-year-olds under care of trainers whose horses had the highest incidence o dorsal metacarpal disease also were the fastest one's. Therefore, fast speed associated with longer distances (700m and trainer are factors that predispose young horses to dorsal metacarpal disease.

  1. The human dorsal action control system develops in the absence of vision.

    Science.gov (United States)

    Fiehler, Katja; Burke, Michael; Bien, Siegfried; Röder, Brigitte; Rösler, Frank

    2009-01-01

    The primate dorsal pathway has been proposed to compute vision for action. Although recent findings suggest that dorsal pathway structures contribute to somatosensory action control as well, it is yet not clear whether or not the development of dorsal pathway functions depends on early visual experience. Using functional magnetic resonance imaging, we investigated the pattern of cortical activation in congenitally blind and matched blindfolded sighted adults while performing kinesthetically guided hand movements. Congenitally blind adults activated similar dorsal pathway structures as sighted controls. Group-specific activations were found in the extrastriate cortex and the auditory cortex for congenitally blind humans and in the precuneus and the presupplementary motor area for sighted humans. Dorsal pathway activity was in addition observed for working memory maintenance of kinesthetic movement information in both groups. Thus, the results suggest that dorsal pathway functions develop in the absence of vision. This favors the idea of a general mechanism of movement control that operates regardless of the sensory input modality. Group differences in cortical activation patterns imply different movement control strategies as a function of visual experience.

  2. Dorsal stream involvement in recognition of objects with transient onset but not with ramped onset

    Directory of Open Access Journals (Sweden)

    Lourenco Tomas

    2011-08-01

    Full Text Available Abstract Background Although the ventral visual stream is understood to be responsible for object recognition, it has been proposed that the dorsal stream may contribute to object recognition by rapidly activating parietal attention mechanisms, prior to ventral stream object processing. Methods To investigate the relative contribution of the dorsal visual stream to object recognition a group of tertiary students were divided into good and poor motion coherence groups and assessed on tasks classically assumed to rely on ventral stream processing. Participants were required to identify simple line drawings in two tasks, one where objects were presented abruptly for 50 ms followed by a white-noise mask, the other where contrast was linearly ramped on and off over 325 ms and replaced with a mask. Results Although both groups only differed in motion coherence performance (a dorsal stream measure, the good motion coherence group showed superior contrast sensitivity for object recognition on the abrupt, but not the ramped presentation tasks. Conclusions We propose that abrupt presentation of objects activated attention mechanisms fed by the dorsal stream, whereas the ramped presentation had reduced transience and thus did not activate dorsal attention mechanisms as well. The results suggest that rapid dorsal stream activation may be required to assist with ventral stream object processing.

  3. Transformaciones del modelo Neogranadino de parroquialización. El caso de la Parroquia San Francisco Xavier de Piedecuesta

    Directory of Open Access Journals (Sweden)

    Luis Rubén Pérez Pinzón

    2013-01-01

    Full Text Available El artículo analiza los fundamentos canónigos, las razones virreinales y los rituales eclesiásticos que justificaron las fundaciones parroquiales del siglo XVIII. Para ello se enfatiza en el modelo de urbanismo de las autoridades borbónicas que sustituyó la práctica de fundaciones de ciudades y villas de los siglos XVI y XVII a partir de capitulaciones. Modelo de necesidades demostradas, visitas a las instituciones virreinales y verificación de méritos que se puede comprobar desde el caso de la parroquia moderna de San Francisco Xavier del Pie de la Cuesta (Santander, Colombia, la cual pasó de ser un sitio irregular a la próspera Villa de San Carlos del siglo XIX.

  4. Le Pérou se remet sur pied grâce à un brain-trust | CRDI - Centre de ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    25 oct. 2010 ... ... travail et des lois régissant les exportations, l'amélioration de la protection du ... L'expérience de trois consortiums de recherche financés par le CRDI ... Le conseil consultatif du secteur public (Consejo Consultivo del Sector ...

  5. Efecto del hialuronato de zinc sobre las úlceras en pacientes con diabetes Zinc hyaluronate effects on ulcers in diabetic patients

    Directory of Open Access Journals (Sweden)

    Fernando Ramos Cuevas

    2007-06-01

    Full Text Available Contexto: La úlcera en el pie diabético es una de las principales complicaciones de la diabetes en extremidades bajas. Del 50 al 70% de las amputaciones en extremidades bajas se realizan a pacientes con diabetes. El hialuronato de zinc ha sido probado en el tratamiento de las úlceras diabéticas del pie con resultados prometedores. Objetivo general: Determinar el grado de eficacia del hialuronato de zinc en la curación de úlceras del pie diabético. Diseño: Ensayo terapéutico abierto al azar. Se les dio seguimiento a los pacientes durante un período de doce semanas de junio a diciembre de 2004. Ubicación: Centro de cuidado terciario. Clínica del Pie Diabético. Pacientes: Fueron seleccionados por muestreo consecutivo cincuenta pacientes con diabetes tipo 2 con úlcera en pie, de ambos sexos y con edades entre los 40 y los 80 años y sin una isquemia más baja de la extremidad. Veinticinco de ellos fueron asignados aleatoriamente al grupo del hialuronato de zinc y el resto al grupo de control (tratamiento convencional. La distribución por sexo de género fue similar en ambos grupos, once del femenino (44% y 14 del masculino (56%. La edad promedio en el grupo de la combinación del ácido hialurónico y zinc fue 56,76 ± 8,78 y en el convencional 60,12 ± 8,42, NS. ningún paciente del grupo de hialuronato de zinc abandonó o fue retirado durante el período del estudio. Un paciente del grupo de control falleció. Intervención: El hialuronato de zinc fue aplicado una vez al día en la superficie de la úlcera después de limpiarla con la solución fisiológica salina. Medida principal del resultado: La eficacia del hialuronato de zinc fue determinada por las semanas que se requirieron para conseguir el cierre completo de la úlcera con el tejido fino epitelial (tiempo curativo medio. Material y métodos: Ensayo clínico controlado. Pacientes con úlceras propias del pie diabético. 1 de julio al 30 de septiembre de 2004, 25 pacientes

  6. Dorsal premotor cortex is involved in switching motor plans

    Science.gov (United States)

    Pastor-Bernier, Alexandre; Tremblay, Elsa; Cisek, Paul

    2012-01-01

    Previous studies have shown that neural activity in primate dorsal premotor cortex (PMd) can simultaneously represent multiple potential movement plans, and that activity related to these movement options is modulated by their relative subjective desirability. These findings support the hypothesis that decisions about actions are made through a competition within the same circuits that guide the actions themselves. This hypothesis further predicts that the very same cells that guide initial decisions will continue to update their activities if an animal changes its mind. For example, if a previously selected movement option suddenly becomes unavailable, the correction will be performed by the same cells that selected the initial movement, as opposed to some different group of cells responsible for online guidance. We tested this prediction by recording neural activity in the PMd of a monkey performing an instructed-delay reach selection task. In the task, two targets were simultaneously presented and their border styles indicated whether each would be worth 1, 2, or 3 juice drops. In a random subset of trials (FREE), the monkey was allowed a choice while in the remaining trials (FORCED) one of the targets disappeared at the time of the GO signal. In FORCED-LOW trials the monkey was forced to move to the less valuable target and started moving either toward the new target (Direct) or toward the target that vanished and then curved to reach the remaining one (Curved). Prior to the GO signal, PMd activity clearly reflected the monkey's subjective preference, predicting his choices in FREE trials even with equally valued options. In FORCED-LOW trials, PMd activity reflected the switch of the monkey's plan as early as 100 ms after the GO signal, well before movement onset (MO). This confirms that the activity is not related to feedback from the movement itself, and suggests that PMd continues to participate in action selection even when the animal changes its mind on

  7. Dissociated repetition deficits in aphasia can reflect flexible interactions between left dorsal and ventral streams and gender-dimorphic architecture of the right dorsal stream.

    Science.gov (United States)

    Berthier, Marcelo L; Froudist Walsh, Seán; Dávila, Guadalupe; Nabrozidis, Alejandro; Juárez Y Ruiz de Mier, Rocío; Gutiérrez, Antonio; De-Torres, Irene; Ruiz-Cruces, Rafael; Alfaro, Francisco; García-Casares, Natalia

    2013-01-01

    Assessment of brain-damaged subjects presenting with dissociated repetition deficits after selective injury to either the left dorsal or ventral auditory pathways can provide further insight on their respective roles in verbal repetition. We evaluated repetition performance and its neural correlates using multimodal imaging (anatomical MRI, DTI, fMRI, and(18)FDG-PET) in a female patient with transcortical motor aphasia (TCMA) and in a male patient with conduction aphasia (CA) who had small contiguous but non-overlapping left perisylvian infarctions. Repetition in the TCMA patient was fully preserved except for a mild impairment in nonwords and digits, whereas the CA patient had impaired repetition of nonwords, digits and word triplet lists. Sentence repetition was impaired, but he repeated novel sentences significantly better than clichés. The TCMA patient had tissue damage and reduced metabolism in the left sensorimotor cortex and insula. DTI showed damage to the left temporo-frontal and parieto-frontal segments of the arcuate fasciculus (AF) and part of the left ventral stream together with well-developed right dorsal and ventral streams, as has been reported in more than one-third of females. The CA patient had tissue damage and reduced metabolic activity in the left temporoparietal cortex with additional metabolic decrements in the left frontal lobe. DTI showed damage to the left temporo-parietal and temporo-frontal segments of the AF, but the ventral stream was spared. The direct segment of the AF in the right hemisphere was also absent with only vestigial remains of the other dorsal subcomponents present, as is often found in males. fMRI during word and nonword repetition revealed bilateral perisylvian activation in the TCMA patient suggesting recruitment of spared segments of the left dorsal stream and right dorsal stream with propagation of signals to temporal lobe structures suggesting a compensatory reallocation of resources via the ventral streams. The

  8. Orígenes del Krausofröbelismo y Masonería

    Directory of Open Access Journals (Sweden)

    Enrique M. UREÑA

    2010-03-01

    Full Text Available RESUMEN: En sendos artículos publicados en esta misma revista hice una primera introducción a los aspectos masónicos y a los educativos de la vida y obra de Krause. El segundo artículo concluía con una referencia al krausofröbelismo y con el anuncio de que pensaba tratar ampliamente este último tema dentro de un estudio monográfico sobre el krausismo alemán del siglo XIX. Este proyecto sigue en pie. Ahora voy a adelantar solamente algunos de los resultados de ese estudio, bajo la perspectiva marcada por el título del presente artículo.

  9. Un oficio del siglo XX: Guillermo Cabrera Infante en su laberinto fílmico

    Directory of Open Access Journals (Sweden)

    Javier Fernández Díaz

    2016-12-01

    Full Text Available El presente trabajo explora las relaciones entre literatura y cine en la obra de Guillermo Cabrera Infante. Para ello presenta dos bloques temáticos interrelacionados. En el primero se sugiere la lectura de Un oficio del siglo XX, un libro generalmente entendido como un conjunto de críticas cinematográficas, como un género híbrido, cercano al ensayo y a la autobiografía. El paratexto y las notas a pie de página del autor resultan clave. La segunda parte es una revisión de los tres guiones que Cabrera Infante escribió para cine a partir de la noción de texto fílmico.

  10. del alcoholismo

    Directory of Open Access Journals (Sweden)

    Rodrigo Arias Duque

    2005-01-01

    Full Text Available Desde el punto de vista farmacológico, es importante comprender qué es el alcohol y cómo actúa en el organismo. No existe una causa simple, sino una interacción complicada de factores neuroquímicos, fisiológicos, psicológicos y sociales que originan y desarrollan esta grave enfermedad fármaco-dependiente. La acción psicofisiológica y farmacodinámica del alcohol es fundamentalmente depresiva, por la reducción de la transmisión sináptica en el sistema nervioso humano. Es un hecho conocido que el consumo excesivo de alcohol causa una disfunción aguda y crónica del cerebro, produciendo trastornos en el sistema nervioso central, presentando alteraciones en la memoria y en las funciones intelectuales como cálculo, comprensión y aprendizaje. A nivel hepático tiene lugar, en su mayoría, el metabolismo del alcohol, produciéndose un hígado graso alcohólico, aumentando el tamaño, terminando en necrosis e inflamación grave del hígado; esto se llama hepatitis alcohólica, y si se sigue consumiendo alcohol se desarrollará la cirrosis. El alcohol también ha estado relacionado con alteraciones del miocardio; se ha constatado en animales de experimentación sanos que tanto la velocidad de contracción del músculo cardiaco y su máxima tensión disminuyen en presencia del alcohol, como consecuencia, la fuerza de cada contracción y el aumento de presión en el ventrículo izquierdo son menores, perdiendo eficacia el corazón como bomba.

  11. Modificación del coeficiente peso/área del pié en relación con la agregación en Tarebia granifera

    Directory of Open Access Journals (Sweden)

    Rodríguez de la Vega Ricardo Alejandro

    2003-01-01

    Full Text Available OBJETIVO: Analizar la dispersión de los ejemplares de una población de Tarebia granifera y su relación con la modificación de los parámetros morfométricos. METODOS: Se colectó por parcelas incluyendo dos tipos de substratos en condiciones opuestas de agregación y se comparó la abundancia relativa tanto entre muestreos, como entre sustratos. Se delimitaron 7 clases de alto a las cuales se les determinó el coeficiente peso/área del pié, el cual se correlacionó con la talla por clase. Se evaluó experimentalmente si los individuos con menor carga del pié tienen mayor persistencia en substratos emergidos, así como la interacción entre dos grupos de clases de alto. RESULTADOS: La diferencia de la abundancia entre los muestreos fue de t=5.874 (p<0.001 y de t=10.15 (p<0.001 entre el substrato rocoso emergido y el arenoso, sólo en condiciones de alta agregación, en las que la carga del pié de los individuos más grandes se reduce con la talla (r=-0.98, p<0.05. Experimentalmente, la abundancia de los ejemplares de tallas opuestas está mutuamente limitada (r=-0.87, p<0.01, la altura del oleaje limita la abundancia de los ejemplares menores (r=-0.94, p<0.001 siendo tolerada por los mayores (r=0.72, p<0.05. La carga promedio del pie disminuye con la altura del oleaje (r=-0.93, p<0.001. CONCLUSIONES: Con elevada agregación los ejemplares mayores emigran hacia substratos de difícil conquista por los menores, que están limitados por la acción mecánica del medio. La disminución de la carga del pie facilita la dispersión de los individuos.

  12. Modificación del coeficiente peso/área del pié en relación con la agregación en Tarebia granifera

    Directory of Open Access Journals (Sweden)

    Ricardo Alejandro Rodríguez de la Vega

    2003-06-01

    Full Text Available OBJETIVO: Analizar la dispersión de los ejemplares de una población de Tarebia granifera y su relación con la modificación de los parámetros morfométricos. METODOS: Se colectó por parcelas incluyendo dos tipos de substratos en condiciones opuestas de agregación y se comparó la abundancia relativa tanto entre muestreos, como entre sustratos. Se delimitaron 7 clases de alto a las cuales se les determinó el coeficiente peso/área del pié, el cual se correlacionó con la talla por clase. Se evaluó experimentalmente si los individuos con menor carga del pié tienen mayor persistencia en substratos emergidos, así como la interacción entre dos grupos de clases de alto. RESULTADOS: La diferencia de la abundancia entre los muestreos fue de t=5.874 (p<0.001 y de t=10.15 (p<0.001 entre el substrato rocoso emergido y el arenoso, sólo en condiciones de alta agregación, en las que la carga del pié de los individuos más grandes se reduce con la talla (r=-0.98, p<0.05. Experimentalmente, la abundancia de los ejemplares de tallas opuestas está mutuamente limitada (r=-0.87, p<0.01, la altura del oleaje limita la abundancia de los ejemplares menores (r=-0.94, p<0.001 siendo tolerada por los mayores (r=0.72, p<0.05. La carga promedio del pie disminuye con la altura del oleaje (r=-0.93, p<0.001. CONCLUSIONES: Con elevada agregación los ejemplares mayores emigran hacia substratos de difícil conquista por los menores, que están limitados por la acción mecánica del medio. La disminución de la carga del pie facilita la dispersión de los individuos.

  13. Dorsal column sensory axons degenerate due to impaired microvascular perfusion after spinal cord injury in rats

    Science.gov (United States)

    Muradov, Johongir M.; Ewan, Eric E.; Hagg, Theo

    2013-01-01

    The mechanisms contributing to axon loss after spinal cord injury (SCI) are largely unknown but may involve microvascular loss as we have previously suggested. Here, we used a mild contusive injury (120 kdyn IH impactor) at T9 in rats focusing on ascending primary sensory dorsal column axons, anterogradely traced from the sciatic nerves. The injury caused a rapid and progressive loss of dorsal column microvasculature and oligodendrocytes at the injury site and penumbra and a ~70% loss of the sensory axons, by 24 hours. To model the microvascular loss, focal ischemia of the T9 dorsal columns was achieved via phototoxic activation of intravenously injected rose bengal. This caused an ~53% loss of sensory axons and an ~80% loss of dorsal column oligodendrocytes by 24 hours. Axon loss correlated with the extent and axial length of microvessel and oligodendrocyte loss along the dorsal column. To determine if oligodendrocyte loss contributes to axon loss, the glial toxin ethidium bromide (EB; 0.3 µg/µl) was microinjected into the T9 dorsal columns, and resulted in an ~88% loss of dorsal column oligodendrocytes and an ~56% loss of sensory axons after 72 hours. EB also caused an ~72% loss of microvessels. Lower concentrations of EB resulted in less axon, oligodendrocyte and microvessel loss, which were highly correlated (R2 = 0.81). These data suggest that focal spinal cord ischemia causes both oligodendrocyte and axon degeneration, which are perhaps linked. Importantly, they highlight the need of limiting the penumbral spread of ischemia and oligodendrocyte loss after SCI in order to protect axons. PMID:23978615

  14. Aplicaciones clínicas del colgajo en cono

    Directory of Open Access Journals (Sweden)

    W. Calderón

    2014-09-01

    Full Text Available Presentamos nuestra experiencia con el uso de un colgajo previamente descrito, el colgajo denominado en cono por la forma final que obtiene, como la de un barquillo de helado con su bocado. Consta de 2 colgajos acoplados: uno de rotación local y otro un avance en V-Y, ambos fasciocutáneos. Realizamos un análisis retrospectivo de 108 pacientes intervenidos entre 2000 y 2013 por lesiones en diferentes partes del organismo, con edades comprendidas entre los 20 y los 52 años, de los cuales 99 fueron varones, y en los que empleamos este tipo de colgajo. Los defectos cubiertos afectaban a las piernas en el 27% de los casos, tobillos en el 10%, planta del pie en el 9%, al talón en el 8% y a otras localizaciones en el resto de los pacientes. Del total, 80 colgajos tuvieron buena evolución (74%, 11 sufrieron dehiscencia mayor (10,2 %, 13 dehiscencia menor (12% y 4 necrosis (3,7 %. Los resultados confirman que el colgajo en cono es versátil, reproducible, sencillo y seguro de realizar, y permite al cirujano plástico resolver problemas quirúrgicos complejos de forma muy segura y a bajo costo.

  15. Quality of pies obtained of the extraction of sunflower and crambe oil for biodiesel under different temperatures; Qualidade das tortas obtidas na extracao do oleo de girassol e crambe para biodiesel sob diferentes temperaturas

    Energy Technology Data Exchange (ETDEWEB)

    Bischoff, Tabata Zingano; Prado, Naimara Vieira do; Coelho, Silvia Renata Machado; Bischoff, Teodato Zingano [Universidade Estadual do Oeste do Parana (UNIOESTE), PR (Brazil)], emails: tabatazbi@yahoo.com.br, nai_mara@hotmail.com, srmcoelho@unioeste.br, teodato_zb@hotmail.com; Figueiredo, Paulo Roberto Abreu de [Instituto Agronomico do Parana (IAPAR), Londrina, PR (Brazil)

    2011-07-01

    Sunflower and crambe are viable alternatives to ethanol. Used in food production, the sunflower crop has economic, rustic and does not require specialized machinery. The crambe oil is concentrated enough, it is feasible to farm and is not edible. The extraction efficiencies of these oils gives to the heating and moisture content of grain. The aim of this study was to evaluate temperatures of oil extraction in sunflower and crambe as pies obtained. For oil extraction and acquisition of pies, we used a high pressure extruder press. The sunflower seed and crambe were extruded without heating and at temperatures of 50 and 70 deg C with three replicates for each treatment, estimated to be the pie, the amount of fat, protein and moisture. Increasing the temperature, we observed a reduction of moisture in sunflower cake, but this did not occur in seeds of crambe. For sunflower, the higher levels of lipids occurred for pie without heating, and for crambe, the higher levels of lipids occurred at 50 deg C. As for the protein, was found in both cultures, the highest level at 70 deg C. It is concluded that the extraction temperature alters the composition of oilseed cakes. (author)

  16. Electroacupuncture reduces the evoked responses of the spinal dorsal horn neurons in ankle-sprained rats

    Science.gov (United States)

    Kim, Jae Hyo; Kim, Hee Young; Chung, Kyungsoon

    2011-01-01

    Acupuncture is shown to be effective in producing analgesia in ankle sprain pain in humans and animals. To examine the underlying mechanisms of the acupuncture-induced analgesia, the effects of electroacupuncture (EA) on weight-bearing forces (WBR) of the affected foot and dorsal horn neuron activities were examined in a rat model of ankle sprain. Ankle sprain was induced manually by overextending ligaments of the left ankle in the rat. Dorsal horn neuron responses to ankle movements or compression were recorded from the lumbar spinal cord using an in vivo extracellular single unit recording setup 1 day after ankle sprain. EA was applied to the SI-6 acupoint on the right forelimb (contralateral to the sprained ankle) by trains of electrical pulses (10 Hz, 1-ms pulse width, 2-mA intensity) for 30 min. After EA, WBR of the sprained foot significantly recovered and dorsal horn neuron activities were significantly suppressed in ankle-sprained rats. However, EA produced no effect in normal rats. The inhibitory effect of EA on hyperactivities of dorsal horn neurons of ankle-sprained rats was blocked by the α-adrenoceptor antagonist phentolamine (5 mg/kg ip) but not by the opioid receptor antagonist naltrexone (10 mg/kg ip). These data suggest that EA-induced analgesia in ankle sprain pain is mediated mainly by suppressing dorsal horn neuron activities through α-adrenergic descending inhibitory systems at the spinal level. PMID:21389301

  17. Opposing dorsal/ventral stream dynamics during figure-ground segregation.

    Science.gov (United States)

    Wokke, Martijn E; Scholte, H Steven; Lamme, Victor A F

    2014-02-01

    The visual system has been commonly subdivided into two segregated visual processing streams: The dorsal pathway processes mainly spatial information, and the ventral pathway specializes in object perception. Recent findings, however, indicate that different forms of interaction (cross-talk) exist between the dorsal and the ventral stream. Here, we used TMS and concurrent EEG recordings to explore these interactions between the dorsal and ventral stream during figure-ground segregation. In two separate experiments, we used repetitive TMS and single-pulse TMS to disrupt processing in the dorsal (V5/HMT⁺) and the ventral (lateral occipital area) stream during a motion-defined figure discrimination task. We presented stimuli that made it possible to differentiate between relatively low-level (figure boundary detection) from higher-level (surface segregation) processing steps during figure-ground segregation. Results show that disruption of V5/HMT⁺ impaired performance related to surface segregation; this effect was mainly found when V5/HMT⁺ was perturbed in an early time window (100 msec) after stimulus presentation. Surprisingly, disruption of the lateral occipital area resulted in increased performance scores and enhanced neural correlates of surface segregation. This facilitatory effect was also mainly found in an early time window (100 msec) after stimulus presentation. These results suggest a "push-pull" interaction in which dorsal and ventral extrastriate areas are being recruited or inhibited depending on stimulus category and task demands.

  18. Detection of genes regulated by Lmx1b during limb dorsalization.

    Science.gov (United States)

    Feenstra, Jennifer M; Kanaya, Kohei; Pira, Charmaine U; Hoffman, Sarah E; Eppey, Richard J; Oberg, Kerby C

    2012-05-01

    Lmx1b is a homeodomain transcription factor that regulates dorsal identity during limb development. Lmx1b knockout (KO) mice develop distal ventral-ventral limbs. Although induction of Lmx1b is linked to Wnt7a expression in the dorsal limb ectoderm, the downstream targets of Lmx1b that accomplish limb dorsalization are unknown. To identify genes targeted by Lmx1b, we compared gene arrays from Lmx1b KO and wild type mouse limbs during limb dorsalization, i.e., 11.5, 12.5, and 13.5 days post coitum. We identified 54 target genes that were differentially expressed in all three stages. Several skeletal targets, including Emx2, Matrilin1 and Matrilin4, demonstrated a loss of scapular expression in the Lmx1b KO mice, supporting a role for Lmx1b in scapula development. Furthermore, the relative abundance of extracellular matrix-related soft tissue targets regulated by Lmx1b, such as collagens and proteoglycans, suggests a mechanism that includes changes in the extracellular matrix composition to accomplish limb dorsalization. Our study provides the most comprehensive characterization of genes regulated by Lmx1b during limb development to-date and provides targets for further investigation. © 2012 The Authors. Development, Growth & Differentiation © 2012 Japanese Society of Developmental Biologists.

  19. Spiny Prey, Fortunate Prey. Dorsal Spines Are an Asset in Intraguild Interactions among Lady Beetles

    Directory of Open Access Journals (Sweden)

    Louis Hautier

    2017-11-01

    Full Text Available The Multicolored Asian Ladybird, Harmonia axyridis, is an extremely successful invasive species. Here we suggest that, in addition to many other traits, the dorsal spines of its larvae contribute to their success, as suggested by behavioral observations of agonistic interactions between H. axyridis and European coccinellids. In coccinellids, the role of dorsal spines in these interactions has been poorly studied and they could be a physical protection against intraguild predators. Dorsal spines of second instar H. axyridis larvae were removed with micro-scissors, which resulted in spineless larvae after molting (spineless group. These larvae were then exposed to starved Coccinella septempunctata larvae. Two control categories were also submitted to interactions: H. axyridis larvae with all their spines (control group and with their spines, but injured by pin stings (injured group. Spine removal at the second instar did not hamper H. axyridis development. The bite rate by C. septempunctata was significantly higher on the spineless H. axyridis and more dorsally located compared to the control and injured groups, while no bite rate difference was observed between the injured and the control group. Our results suggest that in addition to behavioral and chemical defenses, the dorsal spines play a significant protective role against bites. Therefore, spines in ladybirds could be considered as a morphological defense against intraguild predation. In H. axyridis, these defenses might contribute to its success in food resources already exploited by other guild members and thus further facilitate the invasion of new areas.

  20. Culturas del Mundo

    DEFF Research Database (Denmark)

    Benwell, Ann Fenger; Costa, Alberto; Waehle, Espen

    2006-01-01

    ’Culturas del mundo. Colecciones del Museo Nacional de Dinamarca’ with Ann Fenger Benwell in Culturas del Mundo. Colecciones del Museo Nacional de Dinamarca, ed. Silvia Sauquet, Fundación "la Caixa", Barcelona 2006, pp. 31-39......’Culturas del mundo. Colecciones del Museo Nacional de Dinamarca’ with Ann Fenger Benwell in Culturas del Mundo. Colecciones del Museo Nacional de Dinamarca, ed. Silvia Sauquet, Fundación "la Caixa", Barcelona 2006, pp. 31-39...

  1. Study of neoclassical transport and bootstrap current for W7-X in the 1/upsilon regime, using results from the PIES code

    International Nuclear Information System (INIS)

    Nemov, V V; Kalyuzhnyj, V N; Kasilov, S V; Drevlak, M; Nuehrenberg, J; Kernbichler, W; Reiman, A; Monticello, D

    2004-01-01

    For the magnetic field of the Wendelstein 7-X (W7-X) standard high-mirror configuration, computed by the PIES code, taking into account real coil geometry, neoclassical transport and bootstrap current are analysed in the 1/upsilon regime using methods based on the integration along magnetic field lines in a given magnetic field. The zero beta and (beta) = 1% cases are studied. The results are compared to the corresponding results for the vacuum magnetic field directly produced by modular coils. A significant advantage of W7-X over a conventional stellarator resulting from reduced neoclassical transport and from reduced bootstrap current follows from the computations although the neoclassical transport is somewhat larger than that previously obtained for the ideal W7-X model configuration

  2. Diversidad y universalidad como respuesta a pie diabético en paciente paquistaní con diabetes mellitus tipo 2 desde Atención Primaria

    Directory of Open Access Journals (Sweden)

    Montserrat Brugada Faura

    Full Text Available Siguiendo las enseñanzas de Madeleine Leininger sobre los conceptos de su modelo transcultural, buscamos una respuesta en el entorno de la Atención Primaria al caso que nos ocupa de una lesión ulcerosa en pie izquierdo, de etiología desconocida, en paciente paquistaní con diabetes mellitus tipo 2. Hallando la respuesta mediante la adaptación de similitudes de riesgo en el entorno de esta enfermedad, comunes en todas las culturas, y cuyas diferencias estriban en la localización de la úlcera y su factor desencadenante. Anómalas en nuestra cultura al estar relacionada con sus prácticas culturales.

  3. 1. The application of PIE techniques to the study of the corrosion of spent oxide fuel in deep-rock groundwaters. 2. Spent fuel degradation

    International Nuclear Information System (INIS)

    Forsyth, R.S.

    1991-01-01

    During the autumn of 1990, papers summarizing work performed at Studsvik as part of the SKB research programme designed to study the corrosion behaviour of spent nuclear fuel in deep-rock groundwater were presented at two scientific meetings: The first paper presents results and observations of the study of the corrosion of spent oxide fuel in deep-rock ground-waters. The PIE techniques were applied to the detailed study of spent fuel both before and after water contact. The second paper represents an up-dated reporting of results obtained in the Swedish programme relevant to preferential dissolution effects, including interim results from recently stored experiments specifically designed to study possible correlations between corrosion behaviour and fuel properties conditioned by burnup and/or local power variations. Recent observations during the search for corrosion sites in fuel exposed to corrosion for about 4 years are also presented. (KAE)

  4. A century later: Tricolored Pied Flat Coladenia indrani uposathra Fruhstorfer, 1911 (Hesperiidae: Pyrginae and Crenulate Oakblue Apporasa atkinsoni Hewitson, 1869 (Lycaenidae: Theclinae reported from Manipur, India

    Directory of Open Access Journals (Sweden)

    Baleshwor Singh Soibam

    2016-07-01

    Full Text Available The present paper reports the rediscovery of the Tricolored Pied Flat Coladenia indrani uposathra Fruhstorfer, 1911 and Crenulated Oakblue Apporasa atkinsoni Hewitson, 1869 after about 99 years after they were sighted by Tytler (1915 in Irang river and Sebong of Manipur, North East India. C. i. uposathra was sighted a Keibul Lamjao National Park (KLNP and Heibok hills of Imphal valley on 4th and 16th May 2014 and A. atkinsoni was sighted Munnom village at Yaingangpokpi Lokchao Wildlife Sanctuary (YLWS on 8th December 2015.  A. atkinsoni is protected under schedule II of Indian (Wildlife Protection Act 1972. The rediscovery of such very rare species in Manipur shows that more survey is needed in hills and valley regions of Manipur to know the butterfly fauna of the region.

  5. Clasificaciones de lesiones en pie diabético: Un problema no resuelto Classifications of injuries on diabetic foot: A non-solved problem

    Directory of Open Access Journals (Sweden)

    Héctor González de la Torre

    2012-06-01

    Full Text Available La necesidad de unificar criterios empleando un mismo lenguaje que favorezca la comunicación y el intercambio de conocimientos unido al desconocimiento existente en cuanto a las distintas formas de clasificación de las heridas crónicas, ha motivado a los autores para llevar a cabo esta revisión bibliográfica en la que se analizan quince sistemas de clasificación de lesiones de pie diabético y se abordan entre otros, aspectos como la metodología, facilidad de utilización, grado de conocimiento, utilidad de la información aportada y limitaciones de cada uno de ellos. Con ello, los autores no pretenden sino facilitar que los profesionales implicados en el cuidado de las úlceras diabéticas conozcan las distintas formas de estadiaje existentes en el pie diabético y en general en las heridas crónicas.The need of unify criterions using a same idiom contributing communication and interchanging knowledge together with ignorance existing in relation to the different ways of classificating chronic wounds is the reason for the authors to carry out this review analyzing fifteen classification systems in diabetic foot wounds dealing with subjects such as methodology, simplicity of use, grade of knowledge, usefulness of the information provided and limitations of each one. And so the authors pretend helping that those professionals taking care of diabetic foot ulcers can get to know different ways of staging diabetic foot wounds and chronic wounds in general.

  6. The evolution of the dorsal thalamus of jawed vertebrates, including mammals: cladistic analysis and a new hypothesis.

    Science.gov (United States)

    Butler, A B

    1994-01-01

    The evolution of the dorsal thalamus in various vertebrate lineages of jawed vertebrates has been an enigma, partly due to two prevalent misconceptions: the belief that the multitude of nuclei in the dorsal thalamus of mammals could be meaningfully compared neither with the relatively few nuclei in the dorsal thalamus of anamniotes nor with the intermediate number of dorsal thalamic nuclei of other amniotes and a definition of the dorsal thalamus that too narrowly focused on the features of the dorsal thalamus of mammals. The cladistic analysis carried out here allows us to recognize which features are plesiomorphic and which apomorphic for the dorsal thalamus of jawed vertebrates and to then reconstruct the major changes that have occurred in the dorsal thalamus over evolution. Embryological data examined in the context of Von Baerian theory (embryos of later-descendant species resemble the embryos of earlier-descendant species to the point of their divergence) supports a new 'Dual Elaboration Hypothesis' of dorsal thalamic evolution generated from this cladistic analysis. From the morphotype for an early stage in the embryological development of the dorsal thalamus of jawed vertebrates, the divergent, sequential stages of the development of the dorsal thalamus are derived for each major radiation and compared. The new hypothesis holds that the dorsal thalamus comprises two basic divisions--the collothalamus and the lemnothalamus--that receive their predominant input from the midbrain roof and (plesiomorphically) from lemniscal pathways, including the optic tract, respectively. Where present, the collothalamic, midbrain-sensory relay nuclei are homologous to each other in all vertebrate radiations as discrete nuclei. Within the lemnothalamus, the dorsal lateral geniculate nucleus of mammals and the dorsal lateral optic nucleus of non-synapsid amniotes (diapsid reptiles, birds and turtles) are homologous as discrete nuclei; most or all of the ventral nuclear group

  7. Short-term plasticity in turtle dorsal horn neurons mediated by L-type Ca2+ channels

    DEFF Research Database (Denmark)

    Russo, R E; Hounsgaard, J

    1994-01-01

    Windup--the gradual increase of the response--of dorsal horn neurons to repeated activation of primary afferents is an elementary form of short-term plasticity that may mediate central sensitization to pain. In deep dorsal horn neurons of the turtle spinal cord in vitro we report windup of the re......Windup--the gradual increase of the response--of dorsal horn neurons to repeated activation of primary afferents is an elementary form of short-term plasticity that may mediate central sensitization to pain. In deep dorsal horn neurons of the turtle spinal cord in vitro we report windup...

  8. Modality-Based Organization of Ascending Somatosensory Axons in the Direct Dorsal Column Pathway

    Science.gov (United States)

    Niu, Jingwen; Ding, Long; Li, Jian J.; Kim, Hyukmin; Liu, Jiakun; Li, Haipeng; Moberly, Andrew; Badea, Tudor C.; Duncan, Ian D.; Son, Young-Jin; Scherer, Steven S.

    2013-01-01

    The long-standing doctrine regarding the functional organization of the direct dorsal column (DDC) pathway is the “somatotopic map” model, which suggests that somatosensory afferents are primarily organized by receptive field instead of modality. Using modality-specific genetic tracing, here we show that ascending mechanosensory and proprioceptive axons, two main types of the DDC afferents, are largely segregated into a medial–lateral pattern in the mouse dorsal column and medulla. In addition, we found that this modality-based organization is likely to be conserved in other mammalian species, including human. Furthermore, we identified key morphological differences between these two types of afferents, which explains how modality segregation is formed and why a rough “somatotopic map” was previously detected. Collectively, our results establish a new functional organization model for the mammalian direct dorsal column pathway and provide insight into how somatotopic and modality-based organization coexist in the central somatosensory pathway. PMID:24198362

  9. Dorsal free graft urethroplasty for urethral stricture by ventral sagittal urethrotomy approach.

    Science.gov (United States)

    Asopa, H S; Garg, M; Singhal, G G; Singh, L; Asopa, J; Nischal, A

    2001-11-01

    To explore the feasibility of applying a dorsal free graft to treat urethral stricture by the ventral sagittal urethrotomy approach without mobilizing the urethra. Twelve patients with long or multiple strictures of the anterior urethra were treated by a dorsal free full-thickness preputial or buccal mucosa graft. The urethra was not separated from the corporal bodies and was opened in the midline over the stricture. The floor of the urethra was incised, and an elliptical raw area was created over the tunica on which a free full-thickness graft of preputial or buccal mucosa was secured. The urethra was retubularized in one stage. After a follow-up of 8 to 40 months, one recurrence developed and required dilation. The ventral sagittal urethrotomy approach for dorsal free graft urethroplasty is not only feasible and successful, but is easy to perform.

  10. Accelerated forgetting of contextual details due to focal medio-dorsal thalamic lesion

    Directory of Open Access Journals (Sweden)

    Sicong eTu

    2014-09-01

    Full Text Available Effects of thalamic nuclei damage and related white matter tracts on memory performance are still debated. This is particularly evident for the medio-dorsal thalamus which has been less clear in predicting amnesia than anterior thalamus changes. The current study addresses this issue by assessing 7 thalamic stroke patients with consistent unilateral lesions focal to the left medio-dorsal nuclei for immediate and delayed memory performance on standard visual and verbal tests of anterograde memory, and over the long-term (> 24 hrs on an object-location associative memory task. Thalamic patients showed selective impairment to delayed recall, but intact recognition memory. Patients also showed accelerated forgetting of contextual information after a 24 hour delay, compared to controls. Importantly, the mammillothalamic tract was intact in all patients, which suggests a role for the medio-dorsal nuclei in recall and early consolidation memory processes.

  11. Drosophila heart cell movement to the midline occurs through both cell autonomous migration and dorsal closure.

    Science.gov (United States)

    Haack, Timm; Schneider, Matthias; Schwendele, Bernd; Renault, Andrew D

    2014-12-15

    The Drosophila heart is a linear organ formed by the movement of bilaterally specified progenitor cells to the midline and adherence of contralateral heart cells. This movement occurs through the attachment of heart cells to the overlying ectoderm which is undergoing dorsal closure. Therefore heart cells are thought to move to the midline passively. Through live imaging experiments and analysis of mutants that affect the speed of dorsal closure we show that heart cells in Drosophila are autonomously migratory and part of their movement to the midline is independent of the ectoderm. This means that heart formation in flies is more similar to that in vertebrates than previously thought. We also show that defects in dorsal closure can result in failure of the amnioserosa to properly degenerate, which can physically hinder joining of contralateral heart cells leading to a broken heart phenotype. Copyright © 2014 Elsevier Inc. All rights reserved.

  12. [Trombosis of the dorsal penis vein (of Mondor's phlebitis). Presentation of a new case].

    Science.gov (United States)

    Rodríguez Faba, O; Parra Muntaner, L; Gómez Cisneros, S C; Martín Benito, J L; Escaf Barmadah, S

    2006-01-01

    We present a new case of trombosis of the superficial dorsal penis vein called Penile Mondor's disease. The characteristics of the disease are reviewed and the most usual diagnostic and therapeutic methods. The case of a 41 year old man is reviewed who consulted for pain and induration on the proximal part of the penis. After phisical examination and Eco-doppler was made the diagnosis of Mondor's disease. He receibed treatment with non steroidal antiinflamatories and antibiotics. The dorsal vein thrombosis is a rare disease with pain an induration of the dorsal part of the penis. The ethiology can be traumatic, neoplasic, excesive sexual activity or abstinence. Is necesary the diferencial diagnosis with esclerosant linphangitis and the most important imaging is the Eco-doppler. The treatment is based in non steroidal antiinflamatories and antibiotics wit infection. The local aplication of heparine can be useful and the surgery with thrombectomy and resection is for persistent cases.

  13. Gelman: El salario del impío

    Directory of Open Access Journals (Sweden)

    Jorge José Monteleone

    2000-11-01

    Full Text Available En su "Discurso sobre lírica y sociedad", Theodor W Adorno señala que el poema lírico debe presentar un alto "grado de interiorización y una radical individuación". Es decir, que el contenido del poema será tanto más objetivo y motivado socialmente cuanto menos se "tematice" en el la relación entre el yo y la sociedad y que el sujeto estará menos ausente de la forma poética que lo presenta, cuanto mas se sumerja y olvide en la objetividad social del lenguaje. A k luz de esas nociones pueden leerse dos libros de Juan Gelman, que se refieren explícitamente al exilio: Bajo la lluvia ajena (notas al pie de una derrota (1984 y Salarios del impío (1993. Entre uno y otro se percibe una progresiva individuación que permite alcanzar formalmente en el lenguaje poético una eficaz representación imaginaria del hecho histórico opresivo, que elude la reducción temática. Asimismo, la noción de posterioridad, con k cual se reinscribe y reorganiza la significación de un hecho traumático del pasado en un trabajo de la memoria, permitiría revisar aquella célebre advertencia de Adorno según la cual seria imposible escribir poesía después de un genocidio.

  14. Gelman: El salario del impío

    Directory of Open Access Journals (Sweden)

    Jorge José Monteleone

    2001-11-01

    Full Text Available En su "Discurso sobre lírica y sociedad", Theodor W Adorno señala que el poema lírico debe presentar un alto "grado de interiorización y una radical individuación". Es decir, que el contenido del poema será tanto más objetivo y motivado socialmente cuanto menos se "tematice" en el la relación entre el yo y la sociedad y que el sujeto estará menos ausente de la forma poética que lo presenta, cuanto mas se sumerja y olvide en la objetividad social del lenguaje. A k luz de esas nociones pueden leerse dos libros de Juan Gelman, que se refieren explícitamente al exilio: Bajo la lluvia ajena (notas al pie de una derrota (1984 y Salarios del impío (1993. Entre uno y otro se percibe una progresiva individuación que permite alcanzar formalmente en el lenguaje poético una eficaz representación imaginaria del hecho histórico opresivo, que elude la reducción temática. Asimismo, la noción de posterioridad, con k cual se reinscribe y reorganiza la significación de un hecho traumático del pasado en un trabajo de la memoria, permitiría revisar aquella célebre advertencia de Adorno según la cual seria imposible escribir poesía después de un genocidio.

  15. Tactile spatial working memory activates the dorsal extrastriate cortical pathway in congenitally blind individuals.

    Science.gov (United States)

    Bonino, D; Ricciardi, E; Sani, L; Gentili, C; Vanello, N; Guazzelli, M; Vecchi, T; Pietrini, P

    2008-09-01

    In sighted individuals, both the visual and tactile version of the same spatial working memory task elicited neural responses in the dorsal "where" cortical pathway (Ricciardi et al., 2006). Whether the neural response during the tactile working memory task is due to visually-based spatial imagery or rather reflects a more abstract, supramodal organization of the dorsal cortical pathway remains to be determined. To understand the role of visual experience on the functional organization of the dorsal cortical stream, using functional magnetic resonance imaging (fMRI) here we examined brain response in four individuals with congenital or early blindness and no visual recollection, while they performed the same tactile spatial working memory task, a one-back recognition of 2D and 3D matrices. The blind subjects showed a significant activation in bilateral posterior parietal cortex, dorsolateral and inferior prefrontal areas, precuneus, lateral occipital cortex, and cerebellum. Thus, dorsal occipito-parietal areas are involved in mental imagery dealing with spatial components in subjects without prior visual experience and in response to a non-visual task. These data indicate that recruitment of the dorsal cortical pathway in response to the tactile spatial working memory task is not mediated by visually-based imagery and that visual experience is not a prerequisite for the development of a more abstract functional organization of the dorsal stream. These findings, along with previous data indicating a similar supramodal functional organization within the ventral cortical pathway and the motion processing brain regions, may contribute to explain how individuals who are born deprived of sight are able to interact effectively with the surrounding world.

  16. ANALSIS DEL PATRÓN Y LAS PRESIONES PLANTARES DURANTE LA RECEPCIÓN EN UNA COLCHONETA

    Directory of Open Access Journals (Sweden)

    F. Huertas

    2010-10-01

    Full Text Available
    Dentro de las rutinas de la gimnasia deportiva, un elemento común son las
    recepciones sobre la colchoneta. En este sentido, diversos han sido los estudios cinéticos y cinemáticos realizados sobre la recepción y cuyos resultados pueden han sido útiles para la mejora en la compresión de la recepción y diseño de colchonetas. No obstante, el estudio de las presiones plantares durante la recepción no ha sido desarrollado por ninguna
    investigación a pesar de que el pie transmite al cuerpo las cargas de reacción generadas en el contacto con la colchoneta y dependiendo de su magnitud, frecuencia y punto de aplicación se pueden producir diferentes lesiones. El conocimiento de dichas cargas es importante no solo para la prevención de lesiones o criterios en el diseño de colchonetas, sino también para la mejora del rendimiento deportivo, mejorando la estabilidad durante la recepción. El presente trabajo muestra cuales son las zonas del pie a analizar, el patrón y las magnitudes de las presiones plantares durante una recepción tras un salto.

  17. Arte y poder político femenino a través del retrato decimonónico: Manuelita Rosas y Dolores Tosta de Santa Anna

    OpenAIRE

    Leonardini Herane, Nanda

    2017-01-01

    En América Latina, el retrato burgués surge a partir de la Independencia, cuando esta clase, en el poder, comienza a desempeñar un papel decisivo. Es importante precisar que solo a partir de la República las mujeres de los mandatarios empiezan a ser retratadas para establecer su estatus socioeconómico y a veces político. Estudiar detalladamente este tipo de retrato da pie para ver la historia del arte desde un ángulo no tocado: arte, poder y género. El presente artículo aborda dos retratos fe...

  18. Fútbol y política Reflexiones de una relación compleja a través del festival de cine Thinking Football

    OpenAIRE

    Pulleiro Méndez, Carlos

    2015-01-01

    En el presente artículo se van a analizar las complejas y discutidas relaciones entre el fútbol y la política a través de lo que sugieren algunas de las películas que se han mostrado en el festival de cine Thinking Football de 2015. En ellas se refleja a la perfección la multiplicidad de actores políticos del fútbol, lo cual dará pie a considerar si este deporte y su máxima autoridad, la FIFA, tienen un compromiso político propio. Artículo revisado por pares

  19. UNA ESPECIE NUEVA DE RANA DEL GÉNERO CHIASMOCLEIS (MICROHYLIDAE: GASTROPHRYNINAE DE LA CORDILLERA DEL CÓNDOR, ECUADOR

    Directory of Open Access Journals (Sweden)

    ANA ALMENDÁRIZ C.

    Full Text Available RESUMEN Se describe una especie nueva de rana del género Chiasmocleis de los bosques montanos del suroriente del Ecuador, en las laderas occidentales de la Cordillera del Cóndor, entre 1.025-1.630 m de altitud. En base a nuevas secuencias de ADN mitocondrial y nuclear presentamos las relaciones filogenéticas de la nueva especie y sus congéneres. La filogenia muestra una relación cercana a C. antenori, C. carvalhoi, C. magnova, y C. tridactyla. La nueva especie forma parte de un clado integrado por especies que previamente habían sido asignadas al género Syncope. Este clado es hermano de otro conformado por el resto de especies de Chiasmocleis. La nueva especie difiere de sus congéneres por su dorso café ladrillo a café obscuro (sepia cubierto por puntos diminutos blanco-amarillentos. Chiasmocleis parkeri sp. nov. se parece a Chiasmocleis antenori por la ausencia del dedo I, tanto en las manos como en los pies, pero difiere en la coloración, la disposición y tamaño de las manchas claras y la ausencia de una línea clara en la región cantal. La especie nueva presenta algunos rasgos que le distinguen de especies similares. Describimos el canto, caracterizado por tener notas sin pulsos y aportamos datos ecológicos de la localidad típica y áreas adyacentes.

  20. Hábeas Corpus: contribuciones a la causa del estado de derecho

    Directory of Open Access Journals (Sweden)

    Norma Bouyssou

    2016-09-01

    Full Text Available La garantía del hábeas corpus despliega, con total humildad, razones para la permanente expansión de la libertad o bien para su contínuo resguardo. Su bajo perfil, sin embargo, es confundido con indiferencia en orden a su compromiso con la causa de la ciencia del derecho; ello se explica, por un lado, debido a la generalizada creencia que su reconocimiento expreso como derecho positivo -en los más altos niveles normativos-, es anticuerpo suficiente para puestas en peligro o atentados directos contra la autonomía personal a manos del Estado y, por el otro, lógicamente anclado en el predio precedente, en una suerte de desubicación contemporánea frente a un punto de partida de contención teorético (y en desuso del abuso del poder político, al que no obstante se le exigen soluciones con mayor intervención fáctica (y menos frenos en las relaciones sociales, aunque necesariamente adecuadas al orden anterior. Corresponde exponer la disconformidad con los pies en claves propias a la ciencia jurídica, sin hacer a un lado lo pragmático, método dual que se aplicará sobre la excursión que sigue, a la que se invita.

  1. Efecto de la inyección de CaCl2 sobre la suavidad del corte de solomo (Outside

    Directory of Open Access Journals (Sweden)

    Alejandro Chac\\u00F3n-Villalobos

    2007-01-01

    Full Text Available Efecto de la inyección de CaCl2 sobre la suavidad del corte de solomo (Outside. Con el objetivo de determinar el efecto del CaCl2 sobre la suavidad del corte de solomo se utilizaron 100 so lomos (outside con pe so me dio de 2,9 kg, en Alajuela y San José en el año 2000. Ochen ta fue ron inyectados mecánicamente con CaCl2 (3% en una can ti dad equi va len te al 5% del pe so de ca da pieza, empacados al vacío, madurados a 7 ºC durante siete días, y divididos aleatoria mente en cuatro subgrupos de 20 unidades. Un subgrupo se con ge ló a –25 ºC du ran te un mes. El se gun do y ter cero se cocinaron por inmersión en agua ca liente hasta alcanzar una temperatura interna estimada de 70 ºC. Al terminar la cocción el tercer subgrupo se congeló como se describió antes. El cuar to sub gru po so lo se ma du ró y vein te pie zas fres cas constituyeron el grupo control. Se determinó la fuerza de cor te pa ra las 100 pie zas em plean do el mé to do de la Ame rican Meat Scien ce As so cia tion. El pH de las pie zas fres cas y de aquellas sometidas a los procesos de maduración fue determinado. Se estimó la calidad microbiológica y las pérdi das de peso de cada tratamiento. El solomo fresco presentó un pH ba jo (5,4 que no es significativamente incrementado por la maduración con CaCl2 (p > 0,05. Los tra tamientos de cocción presentaron mayores pérdidas de peso y menores mejorías en la sua vidad. To dos los tratamientos aumentaron la sua vi dad ini cial del so lo mo (7,45 kg/cm2 y pre sen ta ron recuentos microbianos aceptables. La inyección seguida de empacado al va cío y maduración generó mejores resultados en la sua vi dad fi nal (3,81 kg/cm2.

  2. Teorías de la justicia distributiva: una fundamentación moral del derecho a la protección de la salud

    Directory of Open Access Journals (Sweden)

    Alejandra Zúñiga-Fajuri

    2011-01-01

    Full Text Available En este artículo se analizan las propuestas desarrolladas por dos de las principales teorías de la justicia distributiva vigentes en la actualidad -el libertarismo y el liberalismo igualitario-, con el fin de revisar los posibles fundamentos morales del derecho al cuidado sanitario. Mientras la teoría de la justicia del libertarismo -que da pie al llamado "mercantilismo sanitario"- avala la idea de que el Estado deje la distribución del cuidado sanitario al libre mercado, el liberalismo igualitario pretende cimentar una obligación directa para el Estado de garantizar un derecho a "cuidado sanitario mínimo" para todos, con base en el principio de igualdad de oportunidades desarrollado por Rawls.

  3. Asociación del dolor podal con variables podométricas, de la práctica deportiva e índice de masa corporal en niños de 12 a 14 años de escuelas de formación deportiva de fútbol de la ciudad de Neiva, 2014

    OpenAIRE

    Ramirez Galvis, Anderson; Utria Tirado, Lorena

    2016-01-01

    El pie es la base de sustentación del ser humano, extremidad utilizada para diferentes actividades de locomoción, capaz de soportar todo el peso corporal incluso en acciones deportivas que implican mantenerla en buenas condiciones. La investigación en el área deportiva continuamente está tomando fuerza con miras en el mejoramiento del rendimiento y la obtención de la forma deportiva incluyendo el buen estado de todos los segmentos corporales implicados, de esta manera se realiza esta investig...

  4. bullwinkle and shark regulate dorsal-appendage morphogenesis in Drosophila oogenesis.

    Science.gov (United States)

    Tran, David H; Berg, Celeste A

    2003-12-01

    bullwinkle (bwk) regulates embryonic anteroposterior patterning and, through a novel germline-to-soma signal, morphogenesis of the eggshell dorsal appendages. We screened for dominant modifiers of the bullwinkle mooseantler eggshell phenotype and identified shark, which encodes an SH2-domain, ankyrin-repeat tyrosine kinase. At the onset of dorsal-appendage formation, shark is expressed in a punctate pattern in the squamous stretch cells overlying the nurse cells. Confocal microscopy with cell-type-specific markers demonstrates that the stretch cells act as a substrate for the migrating dorsal-appendage-forming cells and extend cellular projections towards them. Mosaic analyses reveal that shark is required in follicle cells for cell migration and chorion deposition. Proper shark RNA expression in the stretch cells requires bwk activity, while restoration of shark expression in the stretch cells suppresses the bwk dorsal-appendage phenotype. These results suggest that shark plays an important downstream role in the bwk-signaling pathway. Candidate testing implicates Src42A in a similar role, suggesting conservation with a vertebrate signaling pathway involving non-receptor tyrosine kinases.

  5. Two different streams form the dorsal visual system: anatomy and functions.

    Science.gov (United States)

    Rizzolatti, Giacomo; Matelli, Massimo

    2003-11-01

    There are two radically different views on the functional role of the dorsal visual stream. One considers it as a system involved in space perception. The other is of a system that codes visual information for action organization. On the basis of new anatomical data and a reconsideration of previous functional and clinical data, we propose that the dorsal stream and its recipient parietal areas form two distinct functional systems: the dorso-dorsal stream (d-d stream) and the ventro-dorsal stream (v-d stream). The d-d stream is formed by area V6 (main d-d extrastriate visual node) and areas V6A and MIP of the superior parietal lobule. Its major functional role is the control of actions "on line". Its damage leads to optic ataxia. The v-d stream is formed by area MT (main v-d extrastriate visual node) and by the visual areas of the inferior parietal lobule. As the d-d stream, v-d stream is responsible for action organization. It, however, also plays a crucial role in space perception and action understanding. The putative mechanisms linking action and perception in the v-d stream is discussed.

  6. Postsynaptic dorsal column neurons express NK1 receptors following colon inflammation

    Czech Academy of Sciences Publication Activity Database

    Paleček, Jiří; Palečková, V.; Willis, W. D.

    2003-01-01

    Roč. 116, č. 2 (2003), s. 565-572 ISSN 0306-4522 Grant - others:NIH(US) NS09743; NIH(US) NS11255 Institutional research plan: CEZ:AV0Z5011922 Keywords : visceral pain * substance P * postsynaptic dorsal column Subject RIV: FH - Neurology Impact factor: 3.601, year: 2003

  7. LOCUS-COERULEUS PROJECTIONS TO THE DORSAL MOTOR VAGUS NUCLEUS IN THE RAT

    NARCIS (Netherlands)

    TERHORST, GJ; TOES, GJ; VANWILLIGEN, JD

    1991-01-01

    The origin of the noradrenergic innervation of the preganglionic autonomic nuclei in the medulla oblongata and spinal cord is still controversial. In this investigation descending connections of the locus coeruleus to the dorsal motor vagus nucleus in the rat are studied with Phaseolus vulgaris

  8. Reward Processing by the Dorsal Raphe Nucleus: 5-HT and Beyond

    Science.gov (United States)

    Luo, Minmin; Zhou, Jingfeng; Liu, Zhixiang

    2015-01-01

    The dorsal raphe nucleus (DRN) represents one of the most sensitive reward sites in the brain. However, the exact relationship between DRN neuronal activity and reward signaling has been elusive. In this review, we will summarize anatomical, pharmacological, optogenetics, and electrophysiological studies on the functions and circuit mechanisms of…

  9. The distribution of excitatory amino acid receptors on acutely dissociated dorsal horn neurons from postnatal rats.

    Science.gov (United States)

    Arancio, O; Yoshimura, M; Murase, K; MacDermott, A B

    1993-01-01

    Excitatory amino acid receptor distribution was mapped on acutely dissociated neurons from postnatal rat spinal cord dorsal horn. N-methyl D-aspartate, quisqualate and kainate were applied to multiple locations along the somal and dendritic surfaces of voltage-clamped neurons by means of a pressure application system. To partially compensate for the decrement of response amplitude due to current loss between the site of activation on the dendrite and the recording electrode at the soma, a solution containing 0.15 M KCl was applied on the cell bodies and dendrites of some cells to estimate an empirical length constant. In the majority of the cells tested, the dendritic membrane had regions of higher sensitivity to excitatory amino acid agonists than the somatic membrane, with dendritic response amplitudes reaching more than seven times those at the cell body. A comparison of the relative changes in sensitivity between each combination of two of the three excitatory amino acid agonists along the same dendrite showed different patterns of agonist sensitivity along the dendrite in the majority of the cells. These data were obtained from dorsal horn neurons that had developed and formed synaptic connections in vivo. They demonstrate that in contrast to observations made on ventral horn neurons, receptor density for all the excitatory amino acid receptors on dorsal horn neurons, including the N-methyl-D-aspartate receptor, are generally higher on the dendrites than on the soma. Further, these results are similar to those obtained from dorsal horn neurons grown in culture.

  10. Electrolytic Lesions of the Dorsal Hippocampus Disrupt Renewal of Conditional Fear after Extinction

    Science.gov (United States)

    Ji, Jinzhao; Maren, Stephen

    2005-01-01

    There is a growing body of evidence that the hippocampus is critical for context-dependent memory retrieval. In the present study, we used Pavlovian fear conditioning in rats to examine the role of the dorsal hippocampus (DH) in the context-specific expression of fear memory after extinction (i.e., renewal). Pre-training electrolytic lesions of…

  11. Dorsal inlay buccal mucosal graft (Asopa) urethroplasty for anterior urethral stricture.

    Science.gov (United States)

    Marshall, Stephen D; Raup, Valary T; Brandes, Steven B

    2015-02-01

    Asopa described the inlay of a graft into Snodgrass's longitudinal urethral plate incision using a ventral sagittal urethrotomy approach in 2001. He claimed that this technique was easier to perform and led to less tissue ischemia due to no need for mobilization of the urethra. This approach has subsequently been popularized among reconstructive urologists as the dorsal inlay urethroplasty or Asopa technique. Depending on the location of the stricture, either a subcoronal circumferential incision is made for penile strictures, or a midline perineal incision is made for bulbar strictures. Other approaches for penile urethral strictures include the non-circumferential penile incisional approach and a penoscrotal approach. We generally prefer the circumferential degloving approach for penile urethral strictures. The penis is de-gloved and the urethra is split ventrally to exposure the stricture. It is then deepened to include the full thickness of the dorsal urethra. The dorsal surface is made raw and grafts are fixed on the urethral surface. Quilting sutures are placed to further anchor the graft. A Foley catheter is placed and the urethra is retubularized in two layers with special attention to the staggering of suture lines. The skin incision is then closed in layers. We have found that it is best to perform an Asopa urethroplasty when the urethral plate is ≥1 cm in width. The key to when to use the dorsal inlay technique all depends on the width of the urethral plate once the urethrotomy is performed, stricture etiology, and stricture location (penile vs. bulb).

  12. Dorsal onlay lingual mucosal graft urethroplasty for urethral strictures in women.

    Science.gov (United States)

    Sharma, Girish K; Pandey, Ashwani; Bansal, Harbans; Swain, Sameer; Das, Suren K; Trivedi, Sameer; Dwivedi, Udai S; Singh, Pratap B

    2010-05-01

    To describe the technique and results of dorsal onlay lingual mucosal graft (LMG) urethroplasty for the definitive management of urethral strictures in women. In all, 15 women (mean age 42 years) with a history suggestive of urethral stricture who had undergone multiple urethral dilatations and/or urethrotomy were selected for dorsal onlay LMG urethroplasty after thorough evaluation, from October 2006 to March 2008. After a suprameatal inverted-U incision, the dorsal aspect of the urethra was dissected and urethrotomy was done at the 12 o'clock position across the strictured segment. Tailored LMG harvested from the ventrolateral aspect of the tongue was then sutured to the urethrotomy wound over an 18 F silicone catheter. The preoperative mean maximum urinary flow rate of 7.2 mL/s increased to 29.87 mL/s, 26.95 mL/s and 26.86 mL/s with a 'normal' flow rate curve at 3, 6 and 12 months follow-up, respectively. One patient at the 3-month follow-up had submeatal stenosis and required urethral dilatation thrice at monthly intervals. At the 1-year follow-up, none of the present patients had any neurosensory complications, urinary incontinence, or long-term functional/aesthetic complication at the donor site. LMG urethroplasty using the dorsal onlay technique should be offered for correction of persistent female urethral stricture as it provides a simple, safe and effective approach with durable results.

  13. Nucleocytoplasmic shuttling mediates the dynamic maintenance of nuclear Dorsal levels during Drosophila embryogenesis

    DEFF Research Database (Denmark)

    DeLotto, Robert; DeLotto, Yvonne; Steward, Ruth

    2007-01-01

    , including nuclei on the dorsal side. Nuclear export is blocked by leptomycin B, a potent inhibitor of Exportin 1 (CRM1)-mediated nuclear export. We have developed a novel in vivo assay revealing the presence of a functional leucine-rich nuclear export signal within the carboxyterminal 44 amino acids...

  14. The analgesic effect of clonidine as an adjuvant in dorsal penile ...

    African Journals Online (AJOL)

    Introduction: Dorsal penile nerve block (DPNB) is a commonly performed regional anesthetic technique for male circumcision. The aim of this study was to assess the analgesic effect of the adjunction of clonidine to bupivacaine 0.5% in this block. Methods: It was a prospective randomized double-blind clinical trial including ...

  15. Spatially dynamic recurrent information flow across long-range dorsal motor network encodes selective motor goals.

    Science.gov (United States)

    Yoo, Peter E; Hagan, Maureen A; John, Sam E; Opie, Nicholas L; Ordidge, Roger J; O'Brien, Terence J; Oxley, Thomas J; Moffat, Bradford A; Wong, Yan T

    2018-03-08

    Performing voluntary movements involves many regions of the brain, but it is unknown how they work together to plan and execute specific movements. We recorded high-resolution ultra-high-field blood-oxygen-level-dependent signal during a cued ankle-dorsiflexion task. The spatiotemporal dynamics and the patterns of task-relevant information flow across the dorsal motor network were investigated. We show that task-relevant information appears and decays earlier in the higher order areas of the dorsal motor network then in the primary motor cortex. Furthermore, the results show that task-relevant information is encoded in general initially, and then selective goals are subsequently encoded in specifics subregions across the network. Importantly, the patterns of recurrent information flow across the network vary across different subregions depending on the goal. Recurrent information flow was observed across all higher order areas of the dorsal motor network in the subregions encoding for the current goal. In contrast, only the top-down information flow from the supplementary motor cortex to the frontoparietal regions, with weakened recurrent information flow between the frontoparietal regions and bottom-up information flow from the frontoparietal regions to the supplementary cortex were observed in the subregions encoding for the opposing goal. We conclude that selective motor goal encoding and execution rely on goal-dependent differences in subregional recurrent information flow patterns across the long-range dorsal motor network areas that exhibit graded functional specialization. © 2018 Wiley Periodicals, Inc.

  16. Opposing dorsal/ventral stream dynamics during figure-ground segregation

    NARCIS (Netherlands)

    Wokke, M.E.; Scholte, H.S.; Lamme, V.A.F.

    2014-01-01

    The visual system has been commonly subdivided into two segregated visual processing streams: The dorsal pathway processes mainly spatial information, and the ventral pathway specializes in object perception. Recent findings, however, indicate that different forms of interaction (cross-talk) exist

  17. Excessive D1 Dopamine Receptor Activation in the Dorsal Striatum Promotes Autistic-Like Behaviors.

    Science.gov (United States)

    Lee, Yunjin; Kim, Hannah; Kim, Ji-Eun; Park, Jin-Young; Choi, Juli; Lee, Jung-Eun; Lee, Eun-Hwa; Han, Pyung-Lim

    2018-07-01

    The dopamine system has been characterized in motor function, goal-directed behaviors, and rewards. Recent studies recognize various dopamine system genes as being associated with autism spectrum disorder (ASD). However, how dopamine system dysfunction induces ASD pathophysiology remains unknown. In the present study, we demonstrated that mice with increased dopamine functions in the dorsal striatum via the suppression of dopamine transporter expression in substantia nigra neurons or the optogenetic stimulation of the nigro-striatal circuitry exhibited sociability deficits and repetitive behaviors relevant to ASD pathology in animal models, while these behavioral changes were blocked by a D1 receptor antagonist. Pharmacological activation of D1 dopamine receptors in normal mice or the genetic knockout (KO) of D2 dopamine receptors also produced typical autistic-like behaviors. Moreover, the siRNA-mediated inhibition of D2 dopamine receptors in the dorsal striatum was sufficient to replicate autistic-like phenotypes in D2 KO mice. Intervention of D1 dopamine receptor functions or the signaling pathways-related D1 receptors in D2 KO mice produced anti-autistic effects. Together, our results indicate that increased dopamine function in the dorsal striatum promotes autistic-like behaviors and that the dorsal striatum is the neural correlate of ASD core symptoms.

  18. Dioptrics of the facet lenses in the dorsal rim area of the cricket Gryllus bimaculatus

    NARCIS (Netherlands)

    Ukhanov, KY; Leertouwer, HL; Gribakin, FG; Stavenga, DG

    1996-01-01

    1. The optics of the corneal facet lenses from the dorsal rim area (DRA) and from the dorso-lateral areas (DA) of the compound eye of the cricket Gryllus bimaculatus were studied. 2. The DRA of the cricket eye contains quite normally shaped facet lenses. The diameter of the facet lens in the DA is

  19. Homeobox gene expression in adult dorsal root ganglia: Is regeneration a recapitulation of development?

    NARCIS (Netherlands)

    Vogelaar, C.F.

    2003-01-01

    Neurons of the peripheral nervous system are able to regenerate their peripheral axons after injury, leading to complete recovery of sensory and motor function. The sciatic nerve crush model is frequently used to study peripheral nerve regeneration. Sensory neurons in the dorsal root ganglia (DRGs)

  20. Phenotypic variation in dorsal fin morphology of coastal bottlenose dolphins (Tursiops truncatus off Mexico

    Directory of Open Access Journals (Sweden)

    Eduardo Morteo

    2017-06-01

    Full Text Available Geographic variation in external morphology is thought to reflect an interplay between genotype and the environment. Morphological variation has been well-described for a number of cetacean species, including the bottlenose dolphin (Tursiops truncatus. In this study we analyzed dorsal fin morphometric variation in coastal bottlenose dolphins to search for geographic patterns at different spatial scales. A total of 533 dorsal fin images from 19 available photo-identification catalogs across the three Mexican oceanic regions (Pacific Ocean n = 6, Gulf of California n = 6 and, Gulf of Mexico n = 7 were used in the analysis. Eleven fin shape measurements were analyzed to evaluate fin polymorphism through multivariate tests. Principal Component Analysis on log-transformed standardized ratios explained 94% of the variance. Canonical Discriminant Function Analysis on factor scores showed separation among most study areas (p < 0.05 with exception of the Gulf of Mexico where a strong morphometric cline was found. Possible explanations for the observed differences are related to environmental, biological and evolutionary processes. Shape distinction between dorsal fins from the Pacific and those from the Gulf of California were consistent with previously reported differences in skull morphometrics and genetics. Although the functional advantages of dorsal fin shape remains to be assessed, it is not unlikely that over a wide range of environments, fin shape may represent a trade-off among thermoregulatory capacity, hydrodynamic performance and the swimming/hunting behavior of the species.

  1. Dorsal Branches of Abdominal Aorta in the Rabbit and the European Hare

    Directory of Open Access Journals (Sweden)

    Flešárová S.

    2016-06-01

    Full Text Available The aim of this study was to describe the anatomical arrangement of the branches arising from the dorsal surface of the aorta abdominalis in the rabbit and the hare. The study was carried out on ten adult rabbits and ten adult European hares using the corrosion technique. After the euthanasia, the vascular network was perfused with saline. After polymerization of the casting medium, the maceration was carried out in a KOH solution. We found different variations in; the number of arteries, level of their origin and arrangement. The aa. lumbales of the same level arose by means of a common trunk or their origin was independent. The aa. lumbales VI or aa. lumbales VI et VII originated also from the a. sacralis mediana. By aa. lumbales we found an important interspecies difference in; number, diameter, ramification and density of dorsal branches, which are designated for the dorsal muscles of the body stem. All listed parameters of branches were higher in the hare. This anatomical arrangement of dorsal branches is adapted to the higher movement activity of the hare. According to our results, it can be concluded that the anatomical arrangement of the branches of the aorta abdominalis shows a higher number of variations in the domesticated rabbit in comparison with the hare.

  2. Characterisation of rebound depolarisation in mice deep dorsal horn neurons in vitro.

    Science.gov (United States)

    Rivera-Arconada, Ivan; Lopez-Garcia, Jose A

    2015-09-01

    Spinal dorsal horn neurons constitute the first relay for pain processing and participate in the processing of other sensory, motor and autonomic information. At the cellular level, intrinsic excitability is a factor contributing to network function. In turn, excitability is set by the array of ionic conductance expressed by neurons. Here, we set out to characterise rebound depolarisation following hyperpolarisation, a feature frequently described in dorsal horn neurons but never addressed in depth. To this end, an in vitro preparation of the spinal cord from mice pups was used combined with whole-cell recordings in current and voltage clamp modes. Results show the expression of H- and/or T-type currents in a significant proportion of dorsal horn neurons. The expression of these currents determines the presence of rebound behaviour at the end of hyperpolarising pulses. T-type calcium currents were associated to high-amplitude rebounds usually involving high-frequency action potential firing. H-currents were associated to low-amplitude rebounds less prone to elicit firing or firing at lower frequencies. For a large proportion of neurons expressing both currents, the H-current constitutes a mechanism to ensure a faster response after hyperpolarisations, adjusting the latency of the rebound firing. We conclude that rebound depolarisation and firing are intrinsic factors to many dorsal horn neurons that may constitute a mechanism to integrate somatosensory information in the spinal cord, allowing for a rapid switch from inhibited-to-excited states.

  3. MRI of enlarged dorsal ganglia, lumbar nerve roots, and cranial nerves in polyradiculoneuropathies

    International Nuclear Information System (INIS)

    Castillo, M.; Mukherji, S.K.

    1996-01-01

    This paper describes the MRI findings in four patients with a clinical diagnosis of hypertrophic polyradiculoneuropathies. In two examination of the lumbar spine showed enlarged nerve roots and dorsal ganglia, and similar findings were present in the cervical spine in a third. The cisternal portions of the cranial nerves were enlarged in another patient. MRI allows identification of enlarged nerves in hypertrophic polyradiculopathies. (orig.)

  4. Neuroimaging investigations of dorsal stream processing and effects of stimulus synchrony in schizophrenia.

    Science.gov (United States)

    Sanfratello, Lori; Aine, Cheryl; Stephen, Julia

    2018-05-25

    Impairments in auditory and visual processing are common in schizophrenia (SP). In the unisensory realm visual deficits are primarily noted for the dorsal visual stream. In addition, insensitivity to timing offsets between stimuli are widely reported for SP. The aim of the present study was to test at the physiological level differences in dorsal/ventral stream visual processing and timing sensitivity between SP and healthy controls (HC) using MEG and a simple auditory/visual task utilizing a variety of multisensory conditions. The paradigm included all combinations of synchronous/asynchronous and central/peripheral stimuli, yielding 4 task conditions. Both HC and SP groups showed activation in parietal areas (dorsal visual stream) during all multisensory conditions, with parietal areas showing decreased activation for SP relative to HC, and a significantly delayed peak of activation for SP in intraparietal sulcus (IPS). We also observed a differential effect of stimulus synchrony on HC and SP parietal response. Furthermore, a (negative) correlation was found between SP positive symptoms and activity in IPS. Taken together, our results provide evidence of impairment of the dorsal visual stream in SP during a multisensory task, along with an altered response to timing offsets between presented multisensory stimuli. Copyright © 2018 Elsevier B.V. All rights reserved.

  5. fMRI Evidence for Dorsal Stream Processing Abnormality in Adults Born Preterm

    Science.gov (United States)

    Chaminade, Thierry; Leutcher, Russia Ha-Vinh; Millet, Veronique; Deruelle, Christine

    2013-01-01

    We investigated the consequences of premature birth on the functional neuroanatomy of the dorsal stream of visual processing. fMRI was recorded while sixteen healthy participants, 8 (two men) adults (19 years 6 months old, SD 10 months) born premature (mean gestational age 30 weeks), referred to as Premas, and 8 (two men) matched controls (20…

  6. The functional anatomy of speech perception: Dorsal and ventral processing pathways

    Science.gov (United States)

    Hickok, Gregory

    2003-04-01

    Drawing on recent developments in the cortical organization of vision, and on data from a variety of sources, Hickok and Poeppel (2000) have proposed a new model of the functional anatomy of speech perception. The model posits that early cortical stages of speech perception involve auditory fields in the superior temporal gyrus bilaterally (although asymmetrically). This cortical processing system then diverges into two broad processing streams, a ventral stream, involved in mapping sound onto meaning, and a dorsal stream, involved in mapping sound onto articulatory-based representations. The ventral stream projects ventrolaterally toward inferior posterior temporal cortex which serves as an interface between sound and meaning. The dorsal stream projects dorsoposteriorly toward the parietal lobe and ultimately to frontal regions. This network provides a mechanism for the development and maintenance of ``parity'' between auditory and motor representations of speech. Although the dorsal stream represents a tight connection between speech perception and speech production, it is not a critical component of the speech perception process under ecologically natural listening conditions. Some degree of bi-directionality in both the dorsal and ventral pathways is also proposed. A variety of recent empirical tests of this model have provided further support for the proposal.

  7. GABAergic Neurons of the Rat Dorsal Hippocampus Express Muscarinic Acetylcholine Receptors

    NARCIS (Netherlands)

    van der Zee, E.A.; Luiten, P.G.M.

    1993-01-01

    The expression of muscarinic acetylcholine receptors (mAChRs) in glutamic acid decarboxylase (GAD)-positive cells in the different strata of CA1, CA3, and the dentate gyrus (DG) of the dorsal hippocampus is examined by way of quantitative immunofluorescent double labeling employing M35, the

  8. Burst-generating neurones in the dorsal horn in an in vitro preparation of the turtle spinal cord

    DEFF Research Database (Denmark)

    Russo, R E; Hounsgaard, J

    1996-01-01

    1. In transverse slices of the spinal cord of the turtle, intracellular recordings were used to characterize and analyse the responses to injected current and activation of primary afferents in dorsal horn neurones. 2. A subpopulation of neurones, with cell bodies located centrally in the dorsal...

  9. Demonstration of the dorsal pancreatic artery by CTA to facilitate superselective arterial infusion of stem cells into the pancreas

    International Nuclear Information System (INIS)

    Lin Yuning; Yang Xizhang; Chen Ziqian; Tan Jianming; Zhong Qun; Yang Li; Wu Zhixian

    2012-01-01

    Purpose: To investigate the diagnostic performance of 64-section CTA in the detection of dorsal pancreatic artery before interventional therapy for patients with diabetes. Materials and methods: The study was approved by the institutional ethics committee; written informed consent was obtained. Forty-two consecutive patients with diabetes received an experimental treatment of autologous bone marrow-derived stem cell transplantation by means of infusion into the dorsal pancreatic artery. All cases underwent abdominal CTA before angiography of pancreatic arteries in order to locate the origin and course of dorsal pancreatic artery. Angiography of coeliac artery, splenic artery, common hepatic artery and superior mesenteric artery were performed both in CTA and DSA. Superselective catheterization of dorsal pancreatic artery was carried out for the infusion of stem cell. Sensitivity, specificity and accuracy for the detection of dorsal pancreatic artery with CTA were calculated using DSA images as the reference standard. Results: Thirty-five and thirty-six dorsal pancreatic arteries were detected by CTA and DSA respectively. Dorsal pancreatic artery was not visualized in either CTA or DSA in 5 patients. The sensitivity, specificity and accuracy for CTA were 94.4%, 83.3% and 92.9%. Conclusion: 64-section CTA is accurate for the detection of dorsal pancreatic artery. It may be useful for the facilitation of superselective arterial infusion of stem cells to pancreas.

  10. THE USE OF SPONGOSTAN-WRAPPED DICED CARTILAGE GRAFT FOR OBTANINING A REGULAR DORSAL CONTOUR IN RHINOPLASTY: A PRELIMINARY REPORT

    Directory of Open Access Journals (Sweden)

    Umut Tuncel

    2013-03-01

    Conclusion: As a result, we can say that spongostan wrapped diced cartilages graft seems to be a cheap, safe and effective method for obtaining a nice nasal dorsal contouring as well as for correcting and preventing of dorsal irregularities in rhinoplasty. [J Contemp Med 2013; 3(1.000: 12-16

  11. Poetes a peu de carrer: espais per a la transferència en la nit dels investigadors

    Directory of Open Access Journals (Sweden)

    Mª del Carmen Quiles Cabrera

    2017-12-01

    Full Text Available Bajo el título de este artículo planteamos una reflexión en torno a la transferencia del conocimiento en el ámbito de la educación literaria. Partimos del nuevo concepto de lectura y de lector –espacios en red, programas informáticos-, cuya evolución ha venido marcada por los cambios sociales y tecnológicos, para plantear la necesidad de acercar el hecho literario a los integrantes de cada comunidad y aproximarlos al lenguaje poético desde el juego y la experimentación. Así, describimos la iniciativa que supuso Poetas a pie de calle en la Noche Europea de los Investigadores, en tanto que modelo de transferencia desde las Humanidades y las Ciencias de la Educación.

  12. Irrigación arterial del músculo interóseo y del ligamento accesorio del músculo flexor digital profundo en la mano del caballo Arterial blood supply to the interosseus muscle and accessory ligament of the deep digital flexor tendon in the horse hand

    OpenAIRE

    J. NATALI; R.M. MOINE; M.S. GIGENA; A.M. GALÁN; E. MARTÍN

    1999-01-01

    El objetivo de este trabajo es el estudio del origen y distribución de las ramas arteriales al músculo interóseo y al ligamento accesorio del músculo flexor digital profundo de la mano del caballo. Se disecaron 20 manos a las que les fue inyectada la arteria mediana con látex coloreado. Las ramas arteriales entran al músculo interóseo por la cara dorsal y palmar del cuerpo y por sus bordes medial y lateral. Cada tendón de inserción del músculo interóseo recibió importantes ramas arteriales po...

  13. RESULTS OF DIAGNOSTICAL BLOCK OF LONG DORSAL SACROILIAC LIGAMENT UNDER SONOGRAPHIC CONTROL IN PATIENTS WITH LOW BACK PAIN

    Directory of Open Access Journals (Sweden)

    Yurkovskiy A. M.

    2018-02-01

    Full Text Available Purpose: to improve effectiveness of diagnostic block of long dorsal sacroiliac ligament performed under sonographic control in patients with low back pain caused by pathology of this ligament. Material and methods: the research included 35 patients (average age 46,2±12,5 years with symptoms of low back pain caused by pathology of long dorsal sacroiliac ligament. Diagnostical block of the given ligament was made under ultrasound control. Results: significant pain syndrome reduction was observed in all patients with ligamentopathy of long dorsal sacroiliac ligament. Conclusion: compared to "blind" technique, long dorsal sacroiliac ligament block performed under sonographic control is a more efficient method of verification and treatment for low back pain syndrome in case of long dorsal sacroiliac ligament injury.

  14. Asociación de desórdenes músculo esqueléticos en región cervical, dorsal y lumbar y factores de riesgo psicosocial en conductores de vehículos de carga en una empresa de transporte terrestre en Bogotá, Colombia.

    OpenAIRE

    Bolívar Cuellar, Johana

    2014-01-01

    Este estudio buscó evaluar la asociación de desórdenes músculo esqueléticos en región cervical, dorsal y lumbar identificados mediante el Cuestionario Nórdico en su versión validada al español y los factores de riesgo psicosocial con el Cuestionario del contenido del trabajo (JCQ), en conductores de vehículos de carga de una empresa de transporte terrestre en Bogotá, Colombia; fue un estudio de corte transversal con la participación voluntaria de 125 conductores. Los resultados demostraron m...

  15. Assessing dorsal scute microchemistry for reconstruction of shortnose sturgeon life histories

    Science.gov (United States)

    Altenritter, Matthew E.; Kinnison, Michael T.; Zydlewski, Gayle B.; Secor, David H.; Zydlewski, Joseph D.

    2015-01-01

    The imperiled status of sturgeons worldwide places priority on the identification and protection of critical habitats. We assessed the micro-structural and micro-chemical scope for a novel calcified structure, dorsal scutes, to be used for reconstruction of past habitat use and group separation in shortnose sturgeon (Acipenser brevirostrum). Dorsal scutes contained a dual-layered structure composed of a thin multi-layered translucent zone lying dorsally above a thicker multi-layered zone. Banding in the thick multi-layered zone correlated strongly with pectoral fin spine annuli supporting the presence of chronological structuring that could contain a chemical record of past environmental exposure. Trace element profiles (Sr:Ca), collected using both wavelength dispersive electron microprobe analysis and laser ablation inductively coupled mass spectrometry, suggest scutes record elemental information useful for tracing transitions between freshwater and marine environments. Moreover, mirror-image like Sr:Ca profiles were observed across the dual-zone structuring of the scute that may indicate duplication of the microchemical profile in a single structure. Additional element:calcium ratios measured in natal regions of dorsal scutes (Ba:Ca, Mg:Ca) suggest the potential for further refinement of techniques for identification of river systems of natal origin. In combination, our results provide proof of concept that dorsal scutes possess the necessary properties to be used as structures for reconstructions of past habitat use in sturgeons. Importantly, scutes may be collected non-lethally and with less injury than current structures, like otoliths and fin spines, affording an opportunity for broader application of microchemical techniques.

  16. Ventral and Dorsal Striatum Networks in Obesity: Link to Food Craving and Weight Gain.

    Science.gov (United States)

    Contreras-Rodríguez, Oren; Martín-Pérez, Cristina; Vilar-López, Raquel; Verdejo-Garcia, Antonio

    2017-05-01

    The food addiction model proposes that obesity overlaps with addiction in terms of neurobiological alterations in the striatum and related clinical manifestations (i.e., craving and persistence of unhealthy habits). Therefore, we aimed to examine the functional connectivity of the striatum in excess-weight versus normal-weight subjects and to determine the extent of the association between striatum connectivity and individual differences in food craving and changes in body mass index (BMI). Forty-two excess-weight participants (BMI > 25) and 39 normal-weight participants enrolled in the study. Functional connectivity in the ventral and dorsal striatum was indicated by seed-based analyses on resting-state data. Food craving was indicated with subjective ratings of visual cues of high-calorie food. Changes in BMI between baseline and 12 weeks follow-up were assessed in 28 excess-weight participants. Measures of connectivity in the ventral striatum and dorsal striatum were compared between groups and correlated with craving and BMI change. Participants with excess weight displayed increased functional connectivity between the ventral striatum and the medial prefrontal and parietal cortices and between the dorsal striatum and the somatosensory cortex. Dorsal striatum connectivity correlated with food craving and predicted BMI gains. Obesity is linked to alterations in the functional connectivity of dorsal striatal networks relevant to food craving and weight gain. These neural alterations are associated with habit learning and thus compatible with the food addiction model of obesity. Copyright © 2016 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

  17. Right dorsal colon ultrasonography in normal adult ponies and miniature horses

    Science.gov (United States)

    Zak, Agnieszka; Baron, Monika; Cylna, Marta; Borowicz, Hieronim

    2017-01-01

    The aim of this study was to determine the normal location, wall thickness and motility of the right dorsal colon in adult ponies and miniature horses. The abdominal ultrasonography examination was performed in a study group consisting of 23 ponies and miniature horses and in a control group comprising ten Thoroughbred horses. The procedure was performed in unsedated standing animals. The location and the thickness of the right dorsal colonic wall was examined on the right side of the abdomen between the 10th and the 14th intercostal space. The contractility was recorded in the 12th intercostal space. A comparative analysis between the study group and control group was carried out using the Student’s t-test. Pearson’s linear correlation coefficient was used to calculate the correlation between the thickness of the colonic wall as well as the number of peristaltic movements and age, wither height and body mass of the animals. The right dorsal colon was identified in all the horses in the 12th intercostal space. In all the intercostal spaces the mean ± standard deviation (SD) wall thickness of the right dorsal colon was 0.27 ± 0.03 cm in the horses from the study group and 0.37 ± 0.03 cm in the control horses. The mean number of peristaltic contractions was 4.05 ± 1.07 per minute in the animals from the study group and 1.7 ± 0.46 contractions per minute in the control group. The values of the ultrasonographic wall thickness and peristaltic motility in small breed horses in the present study were different from the values obtained for large breed horses. The study also found that the right dorsal colon in small breed horses is physiologically located in the 12th intercostal space. This suggests that different reference values should be used in small horse breeds when performing an ultrasound examination. PMID:29065146

  18. Identificación de Yarrowia lipolytica (Ascomycota: Hemiascomycetes como contaminante en la obtención de amplificados del gen 28S rRNA de moluscos

    Directory of Open Access Journals (Sweden)

    Jenny Chirinos

    2011-05-01

    Full Text Available En el presente trabajo se identifica una secuencia de DNA no esperada proveniente de los amplificados del gen 28S rRNA de moluscos terrestres. Las extracciones de DNA se realizaron del tejido del pie de caracoles terrestres por el método del CTAB modificado. Las PCRs fueron llevadas a cabo con primers universales para el gen COI e iniciadores diseñados para moluscos, para el marcador 16S rRNA, 28S rRNA y la región ITS-2. Los tamaños aproximados de las bandas de los amplificados de moluscos fueron de 706 pb para el COI, 330 pb para el 16S rRNA, 900 pb para el ITS-2 y 583 pb para el 28S rRNA; un amplificado del último marcador fue de una longitud inesperada, ~340 pb. Las secuencias de DNA fueron comparadas con la base de datos del GenBank mediante el programa BLASTn y la muestra con la banda de tamaño inesperado resultó en un 100% de identidad y cobertura del 99% con el gen 26S rRNA de la levadura Yarrowia lipolytica. El análisis filogenético con Neighbour-Joining y los valores de divergencia confirmaron la identificación, proporcionando resultados que apoyan la ubicación taxonómica de la especie dentro del clado de los Hemiascomycetes.

  19. The relationship between freezing point of milk and milk components and its changes during lactation in Czech Pied and Holstein cows

    Directory of Open Access Journals (Sweden)

    Gustav Chládek

    2005-01-01

    Full Text Available The freezing point of milk (FPM is an instant indicator of violated technological quality of raw milk, especially of dilution. FPM can also vary due to numerous effects associated with changes in milk composition and milk characteristics. Beside the effect of season, phase of lactation, breed, milk yield, sub-clinical mastitis etc. the impacts of nutrition and dietary or metabolic disorders are the most significant and the most frequent (GAJDŮŠEK, 2003. FPM is a relatively stable physical characteristic and due to osmotically active elements it ranges from – 0.510 to – 0.535 °C (HANUŠ et al., 2003b. Recently ŠUSTOVÁ (2001 studied the freezing point of milk in pool samples; she observed seasonal changes in FPM of mixed milk and the effect of different diets on FPM values. KOLOŠTA (2003 looked into the effect of grazing season on FPM. HANUŠ et al. (2003a analysed possible effects of handling of milk components on FPM.The aim of this work was to describe the relationship between FPM and milk components and the impact of breed, number and phase of lactation on FPM. We analysed 328 milk samples in total, out of which 137 samples were of Czech Pied cows and 191 samples of Holstein cows. The effect of number and phase of lactation was evaluated for both breeds together. The greatest coefficients of correlation in total were found between FPM and lactose content (r = 0.600 and solids non fat (r = 0.523. Lower coefficients of correlation were found between FPM and milk fat content (r = 0.235, milk protein content (r = 0.260 and urea concentration (r = 0.256. These coefficients were considerably lower in Holstein cows than in Czech Pied cows. The coefficients of correlation between FPM and number and phase of lactation and somatic cells count were insignificant. The total mean value of FPM was – 0.534 °C. Breed statistically significantly (P<0.01 affected FPM (+0.006 °C in C breed and milk fat content (+0.19 % in H

  20. Osteology of the dorsal vertebrae of the giant titanosaurian sauropod dinosaur Dreadnoughtus schrani from the Late Cretaceous of Argentina

    Directory of Open Access Journals (Sweden)

    Kristyn K. Voegele

    2017-11-01

    Full Text Available Many titanosaurian dinosaurs are known only from fragmentary remains, making comparisons between taxa difficult because they often lack overlapping skeletal elements. This problem is particularly pronounced for the exceptionally large-bodied members of this sauropod clade. Dreadnoughtus schrani is a well-preserved giant titanosaurian from the Upper Cretaceous (Campanian–Maastrichtian Cerro Fortaleza Formation of southern Patagonia, Argentina. Numerous skeletal elements are known for Dreadnoughtus, including seven nearly complete dorsal vertebrae and a partial dorsal neural arch that collectively represent most of the dorsal sequence. Here we build on our previous preliminary description of these skeletal elements by providing a detailed assessment of their serial positional assignments, as well as comparisons of the dorsal vertebrae of Dreadnoughtus with those of other exceptionally large-bodied titanosaurians. Although the dorsal elements of Dreadnoughtus probably belong to two individuals, they exhibit substantial morphological variation that suggests that there is minimal, if any, positional overlap among them. Dreadnoughtus therefore preserves the second-most complete dorsal vertebral series known for a giant titanosaurian that has been described in detail, behind only that of Futalognkosaurus. The dorsal sequence of Dreadnoughtus provides valuable insight into serial variation along the vertebral column of these enormous sauropods. Such variation includes the variable presence of divided spinodiapophyseal laminae and associated spinodiapophyseal fossae. Given that dorsal vertebrae are the only elements that overlap between known remains of most giant titanosaurian taxa, the dorsal series of Dreadnoughtus provides a means to directly compare the morphologies of these sauropods. The dorsal vertebrae of Dreadnoughtus and Futalognkosaurus have dorsoventrally narrow transverse processes, unlike the condition in Puertasaurus. Further

  1. REDESCRIPCIÓN DE POTAMOLITHUS SUPERSULCATUS PILSBRY, 1896 (GASTROPODA, TATEIDAE DEL SUR DE LA CUENCA DEL PLATA

    Directory of Open Access Journals (Sweden)

    MICAELA DE LUCÍA

    Full Text Available RESUMEN El género Potamolithus Pilsbry, 1896 (Gastropoda; Tateidae, posee 31 especies, 22 de las cuales se hayan en la Argentina distribuidas principalmente en la cuenca Del Plata, definiendo al río Uruguay y al Río de la Plata como una zona caliente de diversidad en gasterópodos dulceacuícolas. Sin embargo, la mayoría de sus especies han sido descriptas solo por caracteres conquilógicos y, unas pocas tienen datos anatómicos, conllevando a la descripción de subespecies o morfos que se superponen unos a otros. A Potamolithus lapidum algunos autores le atribuyen cuatro subespecies (con datos conquiológicos, y una con datos parciales de anatomía blanda, sin embargo otros incluyen ocho “morfos”. Aquí nosotros damos un comienzo en el estudio de Potamolithus lapidum elevando a Potamolithus lapidum supersulcatus Pilsbry, 1896 a la categoría de especie, de la cual solo se conocen caracteres conquiológicos y radulares parcialmente. Aportamos datos de: concha, órganos paleales, cabeza, pie, pene, rádula, sistemas reproductor femenino y masculino, sistema nervioso y, secuencia parcial del gen mitocondrial citocromo c oxidasa subunidad I. Es necesario realizar una buena descripción de las especies del género Potamolithus debido a que algunas de las especies ya han sido citadas como especies vulnerables y que habitan ríos que están siendo modificados por la actividad humana y por la presencia del bivalvo invasor Limnoperna fortunei.

  2. Metrología y arquitectura modular en el puerto de La Picola (Santa Pola, Alicante al final del siglo V a.C.

    Directory of Open Access Journals (Sweden)

    Moret, Pierre

    1998-12-01

    Full Text Available La Picola (Santa Pola, Alicante is a fortified port to the south-east of Elche. Built c. 430 BC, it was abandoned within a hundred years. The surviving structures indicate that the same unit of measure was employed at every stage in the building of the port. This foot —equivalent to between 29,7 and 30 cm— is the basis of everything from mud bricks to the settlement's ground-plan. The network of streets and buildings is organised symmetrically, using a five-fathom or 30-foot division; houses are two fathoms or 12 feet wide. This type of modular organisation is probably Greek in origin.El puerto fortificado de La Picola (Santa Pola, situado en la costa alicantina al Sureste de Elche, fue construido hacia 430 a.C. y abandonado al cabo de un siglo. El estudio de las estructuras conservadas demuestra que se utilizó la misma unidad de medida —un pie de 29,7 a 30 cm— en todas las etapas del programa de construcción, desde la fabricación de los adobes hasta las grandes divisiones del plano regulador. La trama de las calles y de las manzanas, organizada en torno a un eje de simetría, se basa en un módulo de 5 brazas (5 x 6 pies, mientras que la anchura de las casas sigue un módulo de 2 brazas (2 x 6 pies. El origen de este esquema modular es probablemente griego.

  3. Il dono del racconto

    DEFF Research Database (Denmark)

    Polito, Paola

    1998-01-01

    L'articolo indaga a vari livelli strutturali del romanzo "Il coraggio del pettirosso" (rete metaforica, dialogismo diegetico, dialogismo come fenomeno di voce, strategie discorsive messe in atto dalla voce narrante, stile colloquiale) la complessa realizzazione testuale del genere narrativo...

  4. Effets de certaines pratiques oenologiques telles que : pied de cuve, sulfitage et régulation du pH sur la flore de fermentation dans les moûts de Xérès

    Directory of Open Access Journals (Sweden)

    Manuel José Valcárcel Muñoz

    1990-06-01

    Les résultats mettent en évidence l'efficacité de l'usage correct du pied de cuve contenant des levures sélectionnées, l'influence relativement faible de la régulation du pH sur la flore blastomicète, et enfin la sélection correcte de la flore par un sulfitage adéquat.

  5. Antropometría del trabajador minero de la altura

    Directory of Open Access Journals (Sweden)

    Augusto V Ramírez

    2006-10-01

    Full Text Available Introducción: La antropometría trata de las medidas del cuerpo humano y es base fundamental para la ergonomía. La minería peruana se localiza casi siempre en la gran altura, hábitat del hombre andino, que tiene características antropométricas diversas al hombre del llano. Objetivo: Caracterizar antropométricamente a una población andina de trabajadores mineros en la sierra central del Perú. Diseño: El estudio fue descriptivo, tipo prospectivo y observacional. Lugar: Servicio de Salud Ocupacional, Centromin-Perú, en La Oroya, y 4 de sus hospitales mineros satélites. Participantes: Tres mil trabajadores mineros, sanos, de sexo masculino, de 21 a 60 años, nativos-residentes alturas superiores a 3 500 msnm. Intervenciones: La muestra la generamos con un modelo aleatorio polietápico de conglomerados. El estudio se realizó entre 1984-1994; obtuvimos media, rango desviación estándar de la media. Para la certeza estadística de la hipótesis de normalidad, aplicamos la prueba de significancia de Shapiro - Wilk, para dos colas. Principales medidas de los resultados: Medidas morfológicas, macroscópicas, fenotípicas y de superficie, realizadas con un protocolo medición y según técnica reconocida en el ámbito científico. Resultados: De los parámetros estudiados destacaron: de pie, estatura 151,2 a 154,6, altura piso-ojos, 1,481 m; sentado, asiento-codo 0,243 m, a vértex y altura ojos, 1,155 y 1,095 m; mano, ancho y largo, 0,104 a 0,171 m; pie, ancho y largo, 0,92 y 0,239 m; perímetro tórax, reposo 98,16, inspiración forzada, 105,3, espiración forzada 94,3 cm. Los resultados fueron validados con la prueba de Shapiro Wilk que, para aceptación, valora entre 0,01 y 0,099. Del total (47, tres parámetros fueron rechazados totalmente: alcance vertical máximo de brazo, ancho de caderas y perímetro de cráneo, cuyo valor de x en los tres casos 0,50. Conclusiones: La caracterización antropométrica del trabajador minero andino

  6. Zīmola nozīme patērētāju lēmuma pieņemšanā mēbeļu mazumtirdzniecībā.

    OpenAIRE

    Pētersons, Miks

    2013-01-01

    Maģistra darba temats ir „Zīmola nozīme patērētāju lēmuma pieņemšanā mēbeļu mazumtirdzniecībā”. Darba mērķis ir teorētiski analizēt un praktiski noskaidrot zīmola nozīmi patērētāja lēmuma pieņemšanā par mēbeļu iegādi. Temats ir aktuāls un darbā apkopotie rezultāti var būt saistoši Latvijas mēbeļu nozares dalībniekiem. 1. nodaļā autors izvērtē patērētāju uzvedību noteicošos faktorus, kā arī zīmola nozīme lēmuma pieņemšanā. 2. nodaļā analizēta mēbeļu ražošanas nozare Latvijā, veikta uzņēm...

  7. Differences between Dorsal and Ventral Striatum in the Sensitivity of Tonically Active Neurons to Rewarding Events

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    Kevin Marche

    2017-07-01

    Full Text Available Within the striatum, cholinergic interneurons, electrophysiologically identified as tonically active neurons (TANs, represent a relatively homogeneous group in terms of their functional properties. They display typical pause in tonic firing in response to rewarding events which are of crucial importance for reinforcement learning. These responses are uniformly distributed throughout the dorsal striatum (i.e., motor and associative striatum, but it is unknown, at least in monkeys, whether differences in the modulation of TAN activity exist in the ventral striatum (i.e., limbic striatum, a region specialized for processing of motivational information. To address this issue, we examined the activity of dorsal and ventral TANs in two monkeys trained on a Pavlovian conditioning task in which a visual stimulus preceded the delivery of liquid reward by a fixed time interval. We found that the proportion of TANs responding to the stimulus predictive of reward did not vary significantly across regions (58%–80%, whereas the fraction of TANs responding to reward was higher in the limbic striatum (100% compared to the motor (65% and associative striatum (52%. By examining TAN modulation at the level of both the population and the individual neurons, we showed that the duration of pause responses to the stimulus and reward was longer in the ventral than in the dorsal striatal regions. Also, the magnitude of the pause was greater in ventral than dorsal striatum for the stimulus predictive of reward but not for the reward itself. We found similar region-specific differences in pause response duration to the stimulus when the timing of reward was less predictable (fixed replaced by variable time interval. Regional variations in the duration and magnitude of the pause response were transferred from the stimulus to reward when reward was delivered in the absence of any predictive stimulus. It therefore appears that ventral TANs exhibit stronger responses to

  8. Nota editorial: Organización de las labores del Instituto de Higiene Social de Cundinamarca

    Directory of Open Access Journals (Sweden)

    Jorge E. Cavelier

    1933-10-01

    Full Text Available Con la fundación del Instituo de Higiene Social de Cundinamarca, la lucha contra las enfermedades  intersexuales ha entrado en un terreno que gracias al apoyo entusiasta de las altas autoridades, promete dar frutos de alta trascendencia para los intereses de la sociedad. El concepto estrecho y perjudicial de considerar las enfermedades venéreas como actos que envuelven culpabilidad, esperamos verlo reemplazado por un concepto más. acorde con las ideas de la higiene moderna, la cual las considera en un pie absoluto de igualdad con entidades como la fiebre tifoidea, y por consiguiente los preceptos generales para combatir las enfermedades contagiosas deben aplicárseles, poniendo de lado prejuicio inaceptables en estos tiempos.

  9. Investigating category- and shape-selective neural processing in ventral and dorsal visual stream under interocular suppression.

    Science.gov (United States)

    Ludwig, Karin; Kathmann, Norbert; Sterzer, Philipp; Hesselmann, Guido

    2015-01-01

    Recent behavioral and neuroimaging studies using continuous flash suppression (CFS) have suggested that action-related processing in the dorsal visual stream might be independent of perceptual awareness, in line with the "vision-for-perception" versus "vision-for-action" distinction of the influential dual-stream theory. It remains controversial if evidence suggesting exclusive dorsal stream processing of tool stimuli under CFS can be explained by their elongated shape alone or by action-relevant category representations in dorsal visual cortex. To approach this question, we investigated category- and shape-selective functional magnetic resonance imaging-blood-oxygen level-dependent responses in both visual streams using images of faces and tools. Multivariate pattern analysis showed enhanced decoding of elongated relative to non-elongated tools, both in the ventral and dorsal visual stream. The second aim of our study was to investigate whether the depth of interocular suppression might differentially affect processing in dorsal and ventral areas. However, parametric modulation of suppression depth by varying the CFS mask contrast did not yield any evidence for differential modulation of category-selective activity. Together, our data provide evidence for shape-selective processing under CFS in both dorsal and ventral stream areas and, therefore, do not support the notion that dorsal "vision-for-action" processing is exclusively preserved under interocular suppression. © 2014 Wiley Periodicals, Inc.

  10. Investigation on cause of outage of Wide Range Monitor (WRM) in High Temperature engineering Test Reactor (HTTR). Post Irradiation Examination (PIE) toward investigation of the cause

    International Nuclear Information System (INIS)

    Shinohara, Masanori; Saito, Kenji; Takada, Shoji; Ishimi, Akihiro; Katsuyama, Kozo; Motegi, Toshihiro

    2012-08-01

    An event, in which one of WRMs were disabled to detect the neutron flux in the reactor core, occurred during the period of reactor shut down of HTTR in March, 2010. The actual life time of WRM was unexpectedly shorter than the past developed life time. Investigation of the cause of the outage of WRM toward the recovery of the life time up to the past developed life is one of the issues to develop the technology basis of High Temperature Gas cooled Reactor (HTGR). Then, two experimental investigations were carried out to reveal the cause of the outage by specifying the damaged part causing the event in the WRM. The one is a post irradiation examination using the X-ray computed tomography scanner in Fuels Monitoring Facility (FMF) to specify the damaged part in the WRM. The other is an experiment using a mock-up simulating the WRM fabricated by the fabricator. The characteristic impedance of the damaged WRM was measured by Time Domain Reflectometry, which was compared with that of the mock-up, which could narrow down the damaged part in the WRM. This report summarized the results of the PIE and the experimental investigation using the mock-up to reveal the cause of outage of WRM. (author)

  11. Favouring more rigour when investigating human eating behaviour is like supporting motherhood and apple pie: A response to Robinson, Bevelander, Field, and Jones (2018).

    Science.gov (United States)

    Hetherington, Marion M; Rolls, Barbara J

    2018-05-11

    In a 1987 paper, addressing questions about factors that influence the initiation, maintenance, and termination of food intake, we wrote, "development of systematic procedures to measure eating behaviour is essential if descriptive and inferential statistics are to be applied to answering such questions, giving them power and replicability" (Hetherington & Rolls, 1987 page 77). Therefore, as longstanding advocates of rigorous procedures in laboratory-based investigations of food intake, we welcome Robinson et al.'s (2018) clear recommendations for laboratory studies. However, this is akin to voting for "motherhood and apple pie", and few would argue against deployment of improved procedures for these studies. What then can we contribute to the debate in order to refine the recommendations made or add to them? Our most important message for researchers is that the central hypothesis or main research question will determine the most appropriate methods for any study. If a laboratory-based study is planned, then there are basic methodological questions that must be answered before proceeding to a final protocol. While such guidelines are needed to ensure basic methodological rigour, these should not be so prescriptive as to inhibit creativity. Here we provide several thoughts on how to advance studies of ingestive behaviour, including the need to apply appropriate controls, encouragement to move beyond convenience samples, and to remember the value of exploratory, observational, and naturalistic studies to complement laboratory-based studies. Copyright © 2018. Published by Elsevier Ltd.

  12. Anatomy and muscle activity of the dorsal fins in bamboo sharks and spiny dogfish during turning maneuvers.

    Science.gov (United States)

    Maia, Anabela; Wilga, Cheryl D

    2013-11-01

    Stability and procured instability characterize two opposing types of swimming, steady and maneuvering, respectively. Fins can be used to manipulate flow to adjust stability during swimming maneuvers either actively using muscle control or passively by structural control. The function of the dorsal fins during turning maneuvering in two shark species with different swimming modes is investigated here using musculoskeletal anatomy and muscle function. White-spotted bamboo sharks are a benthic species that inhabits complex reef habitats and thus have high requirements for maneuverability. Spiny dogfish occupy a variety of coastal and continental shelf habitats and spend relatively more time cruising in open water. These species differ in dorsal fin morphology and fin position along the body. Bamboo sharks have a larger second dorsal fin area and proportionally more muscle insertion into both dorsal fins. The basal and radial pterygiophores are plate-like structures in spiny dogfish and are nearly indistinguishable from one another. In contrast, bamboo sharks lack basal pterygiophores, while the radial pterygiophores form two rows of elongated rectangular elements that articulate with one another. The dorsal fin muscles are composed of a large muscle mass that extends over the ceratotrichia overlying the radials in spiny dogfish. However, in bamboo sharks, the muscle mass is divided into multiple distinct muscles that insert onto the ceratotrichia. During turning maneuvers, the dorsal fin muscles are active in both species with no differences in onset between fin sides. Spiny dogfish have longer burst durations on the outer fin side, which is consistent with opposing resistance to the medium. In bamboo sharks, bilateral activation of the dorsal in muscles could also be stiffening the fin throughout the turn. Thus, dogfish sharks passively stiffen the dorsal fin structurally and functionally, while bamboo sharks have more flexible dorsal fins, which result from a

  13. del cambio

    Directory of Open Access Journals (Sweden)

    Alejandro Canales

    2006-01-01

    Full Text Available El artículo analiza las propuestas y los compromisos en materia de cobertura y de financiamiento en el periodo 2000-2006. En particular, revisa las modificaciones y los ajustes de los tres principales documentos en los que se expresaron las iniciativas: el de la Asociación Nacional de Universidades e Instituciones de Educación Superior, el del equipo de la transición y el programa sectorial. Los resultados muestran que las cifras de atención a la demanda educativa e inversión quedaron lejos de las metas autoimpuestas por el gobierno federal y que será necesario realizar mayores esfuerzos para atender tales desafíos.

  14. The Development of Dorsal Nasal Cyst Formation after Rhinoplasty and Its Reconstruction with Conchal Cartilage

    Directory of Open Access Journals (Sweden)

    Tolgar Lütfi Kumral

    2014-01-01

    Full Text Available The dorsal nasal cyst formation is a rare and late complication of rhinoplasty. It has been rarely reported in the literature and it is usually mucous cysts. Migration and planting to the subcutaneous space during the surgical procedure has been recognized as the formation mechanism. This case report has presented 42-year-old male patient with a destructing dorsal nasal mucous cyst that developed 10 years after the rhinoplasty operation. There was no complication in the primary rhinoplasty and the patient was satisfied with his appearance. There was a swelling of the nasal dorsum over the past year and surgical excision of the cyst was performed. During the surgery, the defect was reconstructed with conchal cartilage. There was no recurrence during follow-up.

  15. Concurrent TMS-fMRI Reveals Interactions between Dorsal and Ventral Attentional Systems

    DEFF Research Database (Denmark)

    Leitao, Joana; Thielscher, Axel; Tuennerhoff, Johannes

    2015-01-01

    interactively in this process. This fMRI study used concurrent transcranial magnetic stimulation (TMS) as a causal perturbation approach to investigate the interactions between dorsal and ventral attentional systems and sensory processing areas. In a sustained spatial attention paradigm, human participants......Adaptive behavior relies on combining bottom-up sensory inputs with top-down control signals to guide responses in line with current goals and task demands. Over the past decade, accumulating evidence has suggested that the dorsal and ventral frontoparietal attentional systems are recruited......-TMS relative to Sham-TMS increased activation in the parietal cortex regardless of sensory stimulation, confirming the neural effectiveness of TMS stimulation. Visual targets increased activations in the anterior insula, a component of the ventral attentional system responsible for salience detection...

  16. Crucial roles of NGF in dorsal horn plasticity in partially deafferentated cats.

    Science.gov (United States)

    Liu, Jia; Chen, Shan-Shan; Dan, Qi-Qin; Rong, Rong; Zhou, Xue; Zhang, Lian-Feng; Wang, Ting-Hua

    2011-04-01

    Though exogenous nerve growth factor (NGF) has been implicated in spinal cord plasticity, whether endogenous NGF plays a crucial role has not been established in vivo. This study investigated first the role of endogenous NGF in spinal dorsal horn (DH) plasticity following removal of L1-L5 and L7-S2 dorsal root ganglions (DRGs) in cats. Co-culture of chick embryo DRG with DH condition media, protein band fishing by cells as well as western blot showed that NGF could promote neurite growth in vitro. Immunohistochemistry and in situ hybridization technique revealed an increase in the NGF and NGF mRNA immunoreactive cells in the DH after partial deafferentation. Lastly, after blocking with NGF antibody, choleragen subunit B horseradish peroxidase (CB-HRP) tracing showed a reduction in the neuronal sprouting observed in the DH. Our results demonstrated that in the cat, endogenous NGF plays a crucial role in DH plasticity after partial deafferentation.

  17. Dorsal medial prefrontal cortex contributes to conditioned taste aversion memory consolidation and retrieval.

    Science.gov (United States)

    Gonzalez, Maria Carolina; Villar, Maria Eugenia; Igaz, Lionel M; Viola, Haydée; Medina, Jorge H

    2015-12-01

    The medial prefrontal cortex (mPFC) is known for its role in decision making and memory processing, including the participation in the formation of extinction memories. However, little is known regarding its contribution to aversive memory consolidation. Here we demonstrate that neural activity and protein synthesis are required in the dorsal mPFC for memory formation of a conditioned taste aversion (CTA) task and that this region is involved in the retrieval of recent and remote long-term CTA memory. In addition, both NMDA receptor and CaMKII activity in dorsal mPFC are needed for CTA memory consolidation, highlighting the complexity of mPFC functions. Copyright © 2015 Elsevier Inc. All rights reserved.

  18. Scanning electron microscopy of the dorsal vessel of Panstrongylus megistus (Burmeister, 1835 (Hemiptera: Reduviidae

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    Nadir Francisca Sant'Anna Nogueira

    1991-03-01

    Full Text Available In this study we analyzed the microanatomy of the dorsal vessel of the triatomine Panstrongylus megistus. The organ is a tuble anatomically divided into an anterior aorta anad a posterior heart, connected to the body wall through 8 pairs of alary muscles. The heart is divided in 3 chambers by means of 2 pairs of cardiac valves. a pair of ostia can be observed in the lateral wall of each chamber. A bundle of nerve fibers was found outside the organ, running dorsally along its major axis. A group of longitudinal muscular fibers was found in the ventral portion of the vessel. The vessel was found to be lined both internally and externally by pericardial cells covered by a thin laminar membrane. Inseide the vessel the pericardial cells were disposed in layers and on the outside they formed clusters or rows.

  19. An amphioxus Msx gene expressed predominantly in the dorsal neural tube.

    Science.gov (United States)

    Sharman, A C; Shimeld, S M; Holland, P W

    1999-04-01

    Genomic and cDNA clones of an Msx class homeobox gene were isolated from amphioxus (Branchiostoma floridae). The gene, AmphiMsx, is expressed in the neural plate from late gastrulation; in later embryos it is expressed in dorsal cells of the neural tube, excluding anterior and posterior regions, in an irregular reiterated pattern. There is transient expression in dorsal cells within somites, reminiscent of migrating neural crest cells of vertebrates. In larvae, mRNA is detected in two patches of anterior ectoderm proposed to be placodes. Evolutionary analyses show there is little phylogenetic information in Msx protein sequences; however, it is likely that duplication of Msx genes occurred in the vertebrate lineage.

  20. [Case of surgical treatment for giant hemangioblastoma in the dorsal medulla oblongata].

    Science.gov (United States)

    Kamoshima, Yuuta; Terasaka, Shunsuke; Shimoda, Yusuke; Kobayashi, Hiroyuki; Kuroda, Satoshi; Asano, Takeshi; Yamaguchi, Shigeru; Murata, Junichi; Houkin, Kiyohiro

    2012-03-01

    Hemangioblastoma in the medulla oblongata is a relatively rare tumor. We present the case of a giant hemangioblastoma occurring in the dorsal medulla oblongata. A 33-year-old man with no neurological symptoms was diagnosed with a hemangioblastoma in the dorsal medulla oblongata, and opted for observation in the outpatient department. After 22 months of observation time, MRI scans showed rapid local tumor progression and obstructive hydrocephalus. At this point, he presented with mild dysphagia as a preoperative neurological deficit. Total surgical removal of the tumor was performed after temporary ventricle drainage and preoperative embolization of the feeding artery. Postoperatively, he became fully conscious but developed bulbar palsy followed by tracheostomy. During the 12 months of postoperative follow-up, severe dysphagia was still present.

  1. Blindness alters the microstructure of the ventral but not the dorsal visual stream

    DEFF Research Database (Denmark)

    Reislev, Nina L; Kupers, Ron; Siebner, Hartwig R

    2016-01-01

    Visual deprivation from birth leads to reorganisation of the brain through cross-modal plasticity. Although there is a general agreement that the primary afferent visual pathways are altered in congenitally blind individuals, our knowledge about microstructural changes within the higher...... pathways in 12 congenitally blind, 15 late blind and 15 normal sighted controls. We also studied six prematurely born individuals with normal vision to control for the effects of prematurity on brain connectivity. Our data revealed a reduction in fractional anisotropy in the ventral but not the dorsal......-order visual streams, and how this is affected by onset of blindness, remains scant. We used diffusion tensor imaging and tractography to investigate microstructural features in the dorsal (superior longitudinal fasciculus) and ventral (inferior longitudinal and inferior fronto-occipital fasciculi) visual...

  2. Social conflict resolution regulated by two dorsal habenular subregions in zebrafish.

    Science.gov (United States)

    Chou, Ming-Yi; Amo, Ryunosuke; Kinoshita, Masae; Cherng, Bor-Wei; Shimazaki, Hideaki; Agetsuma, Masakazu; Shiraki, Toshiyuki; Aoki, Tazu; Takahoko, Mikako; Yamazaki, Masako; Higashijima, Shin-ichi; Okamoto, Hitoshi

    2016-04-01

    When animals encounter conflict they initiate and escalate aggression to establish and maintain a social hierarchy. The neural mechanisms by which animals resolve fighting behaviors to determine such social hierarchies remain unknown. We identified two subregions of the dorsal habenula (dHb) in zebrafish that antagonistically regulate the outcome of conflict. The losing experience reduced neural transmission in the lateral subregion of dHb (dHbL)-dorsal/intermediate interpeduncular nucleus (d/iIPN) circuit. Silencing of the dHbL or medial subregion of dHb (dHbM) caused a stronger predisposition to lose or win a fight, respectively. These results demonstrate that the dHbL and dHbM comprise a dual control system for conflict resolution of social aggression. Copyright © 2016, American Association for the Advancement of Science.

  3. Selective dorsal rhizotomy opportunities with foot deformitiesin children with cerebral palsy

    Directory of Open Access Journals (Sweden)

    Vladimir Markovich Kenis

    2015-03-01

    Full Text Available Foot deformities are the most common orthopedic condition in children with cerebral palsy. The aim of the study was to evaluate the influence of selective dorsal rhizotomy (SDR on foot deformities in children with cerebral palsy. The results were assessed clinically by measurement of changes in muscle spaticity and foot posture. Percentage of resection of dorsal rootlets was from 40 to 90 % of total thickness. The degree of tone reduction had a tendency to be more pronounced in the more proximal muscles and was minimal in calf muscles. Nevertheless, foot posture improved more significantly. That can be explained by generalimprovement of pathological posture at the level of more proximal joints. Thus, SDR has insignificant direct effect on spastic foot deformity and can not be recommended as a basic method of treatment even in pure spasticity. However, SDR should be considered as a part of multidisciplinary management protocol if foot deformity reflects more complex postural disturbance due to generalized spasticity.

  4. Contribution of the dorsal noradrenergic bundle to the effect of amphetamine on acetylcholine turnover

    International Nuclear Information System (INIS)

    Robinson, S.E.

    1986-01-01

    In order to determine the contribution of the noradrenergic projections of the locus coeruleus to the action of amphetamine on cholinergic neurons in several areas of the brain, the dorsal noradrenergic bundle was selectively lesioned by injection of the neurotoxin 6-hydroxydopamine. The bundles of Equithesin-anesthetized male rats were lesioned bilaterally by stereotaxically-placed injections of 6-OHDA. The animals were killed in the microwave and constant rate infusion with phosphoryl ( 2 H 9 )-choline was begun. Levels of ACh and choline and TR /SUB ACh/ were determined by a mass fragmentographic technique. Rats not exhibiting the proper decrease in NE were excluded from all data calculations. It is shown that noradrenergic neurons travelling in the dorsal noradrenergic bundle do not exert a tonic action on cholinergic neurons in the cortex, hippocampus or hypothalamus

  5. Spatially Compact Neural Clusters in the Dorsal Striatum Encode Locomotion Relevant Information.

    Science.gov (United States)

    Barbera, Giovanni; Liang, Bo; Zhang, Lifeng; Gerfen, Charles R; Culurciello, Eugenio; Chen, Rong; Li, Yun; Lin, Da-Ting

    2016-10-05

    An influential striatal model postulates that neural activities in the striatal direct and indirect pathways promote and inhibit movement, respectively. Normal behavior requires coordinated activity in the direct pathway to facilitate intended locomotion and indirect pathway to inhibit unwanted locomotion. In this striatal model, neuronal population activity is assumed to encode locomotion relevant information. Here, we propose a novel encoding mechanism for the dorsal striatum. We identified spatially compact neural clusters in both the direct and indirect pathways. Detailed characterization revealed similar cluster organization between the direct and indirect pathways, and cluster activities from both pathways were correlated with mouse locomotion velocities. Using machine-learning algorithms, cluster activities could be used to decode locomotion relevant behavioral states and locomotion velocity. We propose that neural clusters in the dorsal striatum encode locomotion relevant information and that coordinated activities of direct and indirect pathway neural clusters are required for normal striatal controlled behavior. VIDEO ABSTRACT. Published by Elsevier Inc.

  6. Dietary fat level affecting histochemical radiosensitivity in dorsal aorta in rats

    International Nuclear Information System (INIS)

    Yousri, R.M.; Roushdy, H.M.; EL-Malkh, N.M.; Ashry, M.A.; Soliman, S.M.

    1988-01-01

    The present work has been conducted to investigate the effect of dietary fat status and/or cumulative whole body gamma radiation exposures up to 15 Gy the histochemical pattern of the dorsal aortas of male albino rats. Experimental animals were fed on either fat-rich or fat-free diet and the observations compared with those fed normal fat diet. The histochemical investigations has been confined to the concentration levels of mucopolysaccharide substance and total lipids. The dorsal aorta normal fat group showed higher content of PAS-positive material in the first two layers of the aorta wall in comparison with decreased amount of collagen fibers was shown in fat-rich group

  7. A deepwater fish with 'lightsabers'--dorsal spine-associated luminescence in a counterilluminating lanternshark.

    Science.gov (United States)

    Claes, Julien M; Dean, Mason N; Nilsson, Dan-Eric; Hart, Nathan S; Mallefet, Jérôme

    2013-01-01

    We report the discovery of light organs (photophores) adjacent to the dorsal defensive spines of a small deep-sea lanternshark (Etmopterus spinax). Using a visual modeling based on in vivo luminescence recordings we show that this unusual light display would be detectable by the shark's potential predators from several meters away. We also demonstrate that the luminescence from the spine-associated photophores (SAPs) can be seen through the mineralized spines, which are partially translucent. These results suggest that the SAPs function, either by mimicking the spines' shape or by shining through them, as a unique visual deterrent for predators. This conspicuous dorsal warning display is a surprising complement to the ventral luminous camouflage (counterillumination) of the shark.

  8. A role for Runx transcription factor signaling in dorsal root ganglion sensory neuron diversification.

    Science.gov (United States)

    Kramer, Ina; Sigrist, Markus; de Nooij, Joriene C; Taniuchi, Ichiro; Jessell, Thomas M; Arber, Silvia

    2006-02-02

    Subpopulations of sensory neurons in the dorsal root ganglion (DRG) can be characterized on the basis of sensory modalities that convey distinct peripheral stimuli, but the molecular mechanisms that underlie sensory neuronal diversification remain unclear. Here, we have used genetic manipulations in the mouse embryo to examine how Runx transcription factor signaling controls the acquisition of distinct DRG neuronal subtype identities. Runx3 acts to diversify an Ngn1-independent neuronal cohort by promoting the differentiation of proprioceptive sensory neurons through erosion of TrkB expression in prospective TrkC+ sensory neurons. In contrast, Runx1 controls neuronal diversification within Ngn1-dependent TrkA+ neurons by repression of neuropeptide CGRP expression and controlling the fine pattern of laminar termination in the dorsal spinal cord. Together, our findings suggest that Runx transcription factor signaling plays a key role in sensory neuron diversification.

  9. Anatomical variations in dorsal metatarsal arteries with surgical significance: A cadaveric study

    Directory of Open Access Journals (Sweden)

    Preeti Shivshankar Awari

    2017-01-01

    Full Text Available Introduction: Based on angiosome concept to revascularize a particular artery, the microvascular and reconstructive surgeons must know the anatomy and variations in the arteries in that specific region of the body to achieve better results. Nowadays, dorsal metatarsal artery (DMTA perforator flaps and toe grafts are becoming popular which also demand adequate information about normal anatomy and variants in these arteries for fruitful results. Materials and Methods: The authors studied normal anatomy and variations in the origin of DMTAs in 50 lower extremities of 25 embalmed cadavers. Results: The authors found many variations as the absence of DMTAs, origin of the DMTA from the deep plantar arch. The places wherever the arcuate artery was absent the lateral tarsal artery gave rise to dorsal metatarsal arteries. Conclusion: Being familiar with the incidence of anatomical variations in the origin of the DMTAs can increase vigilance in vascular and reconstructive surgeries leading to better prognosis. surgeries leading to better prognosis.

  10. Agenesis of the dorsal pancreas: systematic review of a clinical challenge

    Directory of Open Access Journals (Sweden)

    Javier A. Cienfuegos

    Full Text Available Background: Agenesis of the dorsal pancreas is a rare malformation. Since 1911 and until 2008, 53 cases have been reported. Several authors have recently described the association of this anomaly with neoplasia of the ventral pancreas, thus we performed a systematic review of the literature from 2008 to 2015. Methods: A systematic review of the Medline and ISI Web of Science Databases from 2008 until 2015 was carried out, and 30 articles which met the inclusion criteria were identified that included a total of 53 patients: 7 children and 46 adults. Conclusions: Although dorsal pancreatic agenesis is a rare malformation, given its association with non-alcoholic pancreatitis and neoplasia of the residual pancreas, physicians should maintain an expectant attitude.

  11. Posicionamiento SEO del Centro de Investigación Flamenco Telethusa: Palabras claves

    Directory of Open Access Journals (Sweden)

    Pedro Corchero Murga

    2016-05-01

    Full Text Available El estudio, clasificación y organización de los metadatos extraídos de los sitios web es una herramienta de gran utilidad para optimizar su posicionamiento. El objetivo de este trabajo es posicionar el web site del Centro de Investigación Flamenco Telethusa. Para ello se han analizado los términos utilizados en los buscadores para encontrar el sitio web de la entidad. Los 10 términos más usados para la búsqueda según el sistema de estadísticas AWStats son los siguientes: flamenco, baile, danza, ballet, estructura, lesiones, telethusa, alegrías, bailar, pie. El uso de estos términos de búsqueda ha sido analizado y compilado por meses y años, desde diciembre de 2008 hasta diciembre de 2014. Los resultados de búsqueda para cada uno de estos términos han sido: flamenco, 9600; baile, 4196; danza, 3147; ballet, 1819; estructura, 1651; lesiones, 989; telethusa, 888; alegrías, 887; bailar, 803; y pie, 851. El número de búsquedas del sitio ha ido aumentando de forma progresiva desde 2009 hasta año 2012 donde alcanzó su máximo. Se produce una disminución durante los años 2013 y 2014. El mes de noviembre, para todos los años, es en el que se produce un mayor número de búsquedas, y el término flamenco el más buscado. Como conclusión proponemos que sea en este mes de noviembre cuando se publiquen contenidos nuevos para satisfacer la demanda de los usuarios.

  12. LA ESTRUCTURA DEL RODAL Y LA FUNCIÓN ECOLÓGICA DEL ARBOLADO EN EL PARQUE CIRCUNDANTE DE HEFEI, PROVINCIA DE ANHUI, CHINA

    Directory of Open Access Journals (Sweden)

    Wang Jianan

    2014-01-01

    Full Text Available El Parque Circundante de la ciudad de Hefei tiene características típicas de bosque urbano. En este investigación se utilizan métodos de ecología de la vegetación para analizar la estructura de la comunidad del parque. La composición de especies, la distribución de alturas de los árboles y el DAP (diámetro a la altura del pecho fueron descritos. Existen 27,662 árboles en el área de estudio, la cual tiene un área de bosque urbano de 42.5 hm2. El DAP promedio fue de 19.2 cm, la densidad en pie fue de 651 árboles·hm2 y el área basal promedio fue de 20.8 m2·hm-2. Con base en la evaluación, los árboles en el parque cuentan con buena salud, pues representaron 53.4 % del total del bosque urbano. Las estructuras de la comunidad fueron analizadas a través del cálculo del índice de crecimiento de los árboles y la correlación de asociación de las especies componentes en el parque. Los resultados muestran que las estructuras de la comunidad en el parque son complejas; existen 22 pares de especies con asociación positiva y, en las siguientes comunidades, los individuos tienen buen crecimiento y son más estables, incluyendo principalmente Platycladus orientalis-Prunus cerasifera f. atropurpurea-Osmanthus fragrans, Robinia pseudoacacia-Ligustrum lucidum, R. pseudoacacia Ginkgo biloba-Photinia serrulata, Populus canadensis-L. lucidum-O. fragrans, Sophora japonica-L. lucidum-Buxus sinica, Cyclobalanopsis glauca-Distylium racemosum.

  13. BMPs regulate msx gene expression in the dorsal neuroectoderm of Drosophila and vertebrates by distinct mechanisms.

    Science.gov (United States)

    Esteves, Francisco F; Springhorn, Alexander; Kague, Erika; Taylor, Erika; Pyrowolakis, George; Fisher, Shannon; Bier, Ethan

    2014-09-01

    In a broad variety of bilaterian species the trunk central nervous system (CNS) derives from three primary rows of neuroblasts. The fates of these neural progenitor cells are determined in part by three conserved transcription factors: vnd/nkx2.2, ind/gsh and msh/msx in Drosophila melanogaster/vertebrates, which are expressed in corresponding non-overlapping patterns along the dorsal-ventral axis. While this conserved suite of "neural identity" gene expression strongly suggests a common ancestral origin for the patterning systems, it is unclear whether the original regulatory mechanisms establishing these patterns have been similarly conserved during evolution. In Drosophila, genetic evidence suggests that Bone Morphogenetic Proteins (BMPs) act in a dosage-dependent fashion to repress expression of neural identity genes. BMPs also play a dose-dependent role in patterning the dorsal and lateral regions of the vertebrate CNS, however, the mechanism by which they achieve such patterning has not yet been clearly established. In this report, we examine the mechanisms by which BMPs act on cis-regulatory modules (CRMs) that control localized expression of the Drosophila msh and zebrafish (Danio rerio) msxB in the dorsal central nervous system (CNS). Our analysis suggests that BMPs act differently in these organisms to regulate similar patterns of gene expression in the neuroectoderm: repressing msh expression in Drosophila, while activating msxB expression in the zebrafish. These findings suggest that the mechanisms by which the BMP gradient patterns the dorsal neuroectoderm have reversed since the divergence of these two ancient lineages.

  14. BMPs regulate msx gene expression in the dorsal neuroectoderm of Drosophila and vertebrates by distinct mechanisms.

    Directory of Open Access Journals (Sweden)

    Francisco F Esteves

    2014-09-01

    Full Text Available In a broad variety of bilaterian species the trunk central nervous system (CNS derives from three primary rows of neuroblasts. The fates of these neural progenitor cells are determined in part by three conserved transcription factors: vnd/nkx2.2, ind/gsh and msh/msx in Drosophila melanogaster/vertebrates, which are expressed in corresponding non-overlapping patterns along the dorsal-ventral axis. While this conserved suite of "neural identity" gene expression strongly suggests a common ancestral origin for the patterning systems, it is unclear whether the original regulatory mechanisms establishing these patterns have been similarly conserved during evolution. In Drosophila, genetic evidence suggests that Bone Morphogenetic Proteins (BMPs act in a dosage-dependent fashion to repress expression of neural identity genes. BMPs also play a dose-dependent role in patterning the dorsal and lateral regions of the vertebrate CNS, however, the mechanism by which they achieve such patterning has not yet been clearly established. In this report, we examine the mechanisms by which BMPs act on cis-regulatory modules (CRMs that control localized expression of the Drosophila msh and zebrafish (Danio rerio msxB in the dorsal central nervous system (CNS. Our analysis suggests that BMPs act differently in these organisms to regulate similar patterns of gene expression in the neuroectoderm: repressing msh expression in Drosophila, while activating msxB expression in the zebrafish. These findings suggest that the mechanisms by which the BMP gradient patterns the dorsal neuroectoderm have reversed since the divergence of these two ancient lineages.

  15. Regular dorsal dimples and damaged mites of Varroa destructor in some Iranian honey bees (Apis mellifera)

    OpenAIRE

    Ardestani, Masoud M.; Ebadi, Rahim; Tahmasbi, Gholamhossein

    2011-01-01

    The frequency of damaged Varroa destructor Anderson and Trueman (Mesostigmata: Varroidae) found on the bottom board of hives of the honey bee, Apis mellifera L. (Hymenoptera: Apidae) has been used as an indicator of the degree of tolerance or resistance of honey bee colonies against mites. However, it is not clear that this measure is adequate. These injuries should be separated from regular dorsal dimples that have a developmental origin. To investigate damage to Varroa mites and regular dor...

  16. Optic ataxia and the function of the dorsal stream: contributions to perception and action.

    Science.gov (United States)

    Pisella, Laure; Sergio, Lauren; Blangero, Annabelle; Torchin, Héloïse; Vighetto, Alain; Rossetti, Yves

    2009-12-01

    Optic ataxia (OA) is one of the symptoms pertaining to Bálint's Syndrome. It has been described clinically for nearly 80 years before it became a cornerstone of the most popular dual stream theory of the visual brain. Over the last 10 years a regain of interest for this neurological condition lead to a number of precise analyses of the deficits found in optic ataxia, giving rise to a renewed outline of its very definition and hence of the function(s) of the occipito-parietal (dorsal) stream. In absence of concomitant clinical symptoms, we review evidence that misreaching errors in central vision result from the "hand effect": an erroneous dynamic spatial processing of proprioceptive information from the hand. When visual feedback of the hand is provided (closed-loop condition), pure optic ataxia is restricted to peripheral vision. This central versus peripheral vision distinction is repeatedly used to argue that action and perception are not unique and dissociated systems. New assessments of optic ataxia patients are provided, confirming on one hand that their visuomotor deficit is specific to peripheral vision (i.e. when the gaze and the hand goals are dissociated), on the other hand that they disclose perceptual deficits in peripheral vision. These results are coherent with the recent demonstration that optic ataxia patients exhibit a general contralesional deficit for dynamic visuo-spatial processing, affecting both hand and eye movements [Gaveau, V., Pélisson, D., Blangero, A., Urquizar, C., Prablanc, C.,Vighetto, A., et al. (2008). A common parietal module for saccade and reach: Eye-hand coordination and saccadic control in optic ataxia. Neuropsychologia, 46, 475-486]. Such module(s) within the dorsal stream could be used for both action and perception in the periphery. It is concluded that optic ataxia cannot be considered as a unitary and specific visuo-manual deficit, and that the modular organisation of the dorsal stream allows for numerous dorsal

  17. The endocannabinoid system within the dorsal lateral geniculate nucleus of the vervet monkey

    DEFF Research Database (Denmark)

    Javadi, P.; Bouskila, J.; Bouchard, J. -F.

    2015-01-01

    The endocannabinoid system mainly consists of cannabinoid receptors type 1 (CB1R) and type 2 (CB2R), their endogenous ligands termed endocannabinoids (eCBs), and the enzymes responsible for the synthesis and degradation of eCBs. These cannabinoid receptors have been well characterized in rodent a...... layers may explain some of the behavioral effects of cannabinoids associated with the integrity of the dorsal visual pathway that plays a role in visual-spatial localization and motion perception....

  18. Dorsal bundle lesions do not affect latent inhibition of conditioned suppression.

    Science.gov (United States)

    Tsaltas, E; Preston, G C; Rawlins, J N; Winocur, G; Gray, J A

    1984-01-01

    Three experiments are reported which examine the effects of lesions of the dorsal ascending noradrenergic bundle (DB) on latent inhibition using a conditioned suppression procedure in rats. In none of the experiments did the DB lesion have any effect, despite changes in the extent of latent inhibition and in the control procedures used to assess it. The results are discussed in relation to the attentional theory of DB function.

  19. Extrasynaptic glycine receptors of rodent dorsal raphe serotonergic neurons:a sensitive target for ethanol

    OpenAIRE

    Maguire, Edward P.; Mitchell, Elizabeth A.; Greig, Scott J.; Corteen, Nicole; Balfour, David J. K.; Swinny, Jerome; Lambert, Jeremy J.; Belelli, Delia

    2014-01-01

    Alcohol abuse is a significant medical and social problem. Several neurotransmitter systems are implicated in ethanol's actions, with certain receptors and ion channels emerging as putative targets. The dorsal raphe (DR) nucleus is associated with the behavioral actions of alcohol, but ethanol actions on these neurons are not well understood. Here, using immunohistochemistry and electrophysiology we characterize DR inhibitory transmission and its sensitivity to ethanol. DR neurons exhibit inh...

  20. Luxations carpo-métacarpiennes dorsales du quatrième et ...

    African Journals Online (AJOL)

    Nous rapportons le cas d'une luxation carpo-métacarpienne dorsale quatrième et cinquième métacarpiens chez un jeune homme de 46 ans, droitier, agent de sécurité, qui à la suite d'un coup d'énervement donne un coup poing contre le mur (mécanisme indirect) entrainant une douleur et impotence fonctionnelle totale de ...

  1. Functional differences between neurochemically defined populations of inhibitory interneurons in the rat spinal dorsal horn ?

    OpenAIRE

    Polg?r, Erika; Sardella, Thomas C.P.; Tiong, Sheena Y.X.; Locke, Samantha; Watanabe, Masahiko; Todd, Andrew J.

    2013-01-01

    In order to understand how nociceptive information is processed in the spinal dorsal horn we need to unravel the complex synaptic circuits involving interneurons, which constitute the vast majority of the neurons in laminae I?III. The main limitation has been the difficulty in defining functional populations among these cells. We have recently identified 4 non-overlapping classes of inhibitory interneuron, defined by expression of galanin, neuropeptide Y (NPY), neuronal nitric oxide synthase ...

  2. Suramin affects capsaicin responses and capsaicin-noxious heat interactions in rat dorsal root ganglia neurones

    Czech Academy of Sciences Publication Activity Database

    Vlachová, Viktorie; Lyfenko, Alla; Vyklický st., Ladislav; Orkand, R. K.

    2002-01-01

    Roč. 51, č. 2 (2002), s. 193-198 ISSN 0862-8408 R&D Projects: GA ČR GA305/00/1639; GA MŠk LN00B122 Institutional research plan: CEZ:AV0Z5011922 Keywords : dorsal root ganglia neurones * vanilloid receptor * capsaicin-noxious heat Subject RIV: ED - Physiology Impact factor: 0.984, year: 2002

  3. Frontal Parietal Control Network Regulates the Anti-Correlated Default and Dorsal Attention Networks

    OpenAIRE

    Gao, Wei; Lin, Weili

    2011-01-01

    Recent reports demonstrate the anti-correlated behaviors between the default and the dorsal attention (DA) networks. We aimed to investigate the roles of the frontal parietal control (FPC) network in regulating the two anti-correlated networks through three experimental conditions, including resting, continuous self-paced/attended sequential finger tapping (FT), and natural movie watching (MW), respectively. The two goal-directed tasks were chosen to engage either one of the two competing net...

  4. Dorsal-ventral patterning in amphioxus: current understanding, unresolved issues, and future directions

    Czech Academy of Sciences Publication Activity Database

    Kozmiková, Iryna; Yu, J.K.

    2017-01-01

    Roč. 61, č. 10-12 (2017), s. 601-610 ISSN 0214-6282 R&D Projects: GA ČR GC15-21285J Institutional support: RVO:68378050 Keywords : dorsal-ventral patterning * organizer * signaling pathway * chordate * evolution Subject RIV: EB - Genetics ; Molecular Biology OBOR OECD: Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology Impact factor: 1.981, year: 2016

  5. Selective Entrainment of Theta Oscillations in the Dorsal Stream Causally Enhances Auditory Working Memory Performance.

    Science.gov (United States)

    Albouy, Philippe; Weiss, Aurélien; Baillet, Sylvain; Zatorre, Robert J

    2017-04-05

    The implication of the dorsal stream in manipulating auditory information in working memory has been recently established. However, the oscillatory dynamics within this network and its causal relationship with behavior remain undefined. Using simultaneous MEG/EEG, we show that theta oscillations in the dorsal stream predict participants' manipulation abilities during memory retention in a task requiring the comparison of two patterns differing in temporal order. We investigated the causal relationship between brain oscillations and behavior by applying theta-rhythmic TMS combined with EEG over the MEG-identified target (left intraparietal sulcus) during the silent interval between the two stimuli. Rhythmic TMS entrained theta oscillation and boosted participants' accuracy. TMS-induced oscillatory entrainment scaled with behavioral enhancement, and both gains varied with participants' baseline abilities. These effects were not seen for a melody-comparison control task and were not observed for arrhythmic TMS. These data establish theta activity in the dorsal stream as causally related to memory manipulation. VIDEO ABSTRACT. Copyright © 2017 Elsevier Inc. All rights reserved.

  6. Adult neurogenesis is reduced in the dorsal hippocampus of rats displaying learned helplessness behavior.

    Science.gov (United States)

    Ho, Y C; Wang, S

    2010-11-24

    Clinical and preclinical studies suggest that the hippocampus has a role in the pathophysiology of major depression. In the learned helplessness (LH) animal model of depression after inescapable shocks (ISs) animals that display LH behavior have reduced cell proliferation in the hippocampus; this effect can be reversed by antidepressant treatment. Using this model, we compared rats that displayed LH behavior and rats that did not show LH behavior (NoLH) after ISs to determine whether reduced hippocampal cell proliferation is associated with the manifestation of LH behavior or is a general response to stress. Specifically, we examined cell proliferation, neurogenesis, and synaptic function in dorsal and ventral hippocampus of LH and NoLH animals and control rats that were not shocked. The LH rats had showed reduced cell proliferation, neurogenesis, and synaptic transmission in the dorsal hippocampus, whereas no changes were seen in the ventral hippocampus. These changes were not observed in the NoLH animals. In a group of NoLH rats that received the same amount of electrical shock as the LH rats to control for the unequal shocks received in these two groups, we observed changes in Ki-67(+) cells associated with acute stress. We conclude that reduced hippocampal cell proliferation and neurogenesis are associated with the manifestation of LH behavior and that the dorsal hippocampus is the most affected area. Copyright © 2010 IBRO. Published by Elsevier Ltd. All rights reserved.

  7. The dorsal skinfold chamber: window into the dynamic interaction of biomaterials with their surrounding host tissue

    Directory of Open Access Journals (Sweden)

    MW Laschke

    2011-09-01

    Full Text Available The implantation of biomaterials into the human body has become an indispensable part of almost all fields of modern medicine. Accordingly, there is an increasing need for appropriate approaches, which can be used to evaluate the suitability of different biomaterials for distinct clinical indications. The dorsal skinfold chamber is a sophisticated experimental model, which has been proven to be extremely valuable for the systematic in vivo analysis of the dynamic interaction of small biomaterial implants with the surrounding host tissue in rats, hamsters and mice. By means of intravital fluorescence microscopy, this chronic model allows for repeated analyses of various cellular, molecular and microvascular mechanisms, which are involved in the early inflammatory and angiogenic host tissue response to biomaterials during the initial 2-3 weeks after implantation. Therefore, the dorsal skinfold chamber has been broadly used during the last two decades to assess the in vivo performance of prosthetic vascular grafts, metallic implants, surgical meshes, bone substitutes, scaffolds for tissue engineering, as well as for locally or systemically applied drug delivery systems. These studies have contributed to identify basic material properties determining the biocompatibility of the implants and vascular ingrowth into their surface or internal structures. Thus, the dorsal skinfold chamber model does not only provide deep insights into the complex interactions of biomaterials with the surrounding soft tissues of the host but also represents an important tool for the future development of novel biomaterials aiming at an optimisation of their biofunctionality in clinical practice.

  8. Supersensitive detection and discrimination of enantiomers by dorsal olfactory receptors: evidence for hierarchical odour coding.

    Science.gov (United States)

    Sato, Takaaki; Kobayakawa, Reiko; Kobayakawa, Ko; Emura, Makoto; Itohara, Shigeyoshi; Kizumi, Miwako; Hamana, Hiroshi; Tsuboi, Akio; Hirono, Junzo

    2015-09-11

    Enantiomeric pairs of mirror-image molecular structures are difficult to resolve by instrumental analyses. The human olfactory system, however, discriminates (-)-wine lactone from its (+)-form rapidly within seconds. To gain insight into receptor coding of enantiomers, we compared behavioural detection and discrimination thresholds of wild-type mice with those of ΔD mice in which all dorsal olfactory receptors are genetically ablated. Surprisingly, wild-type mice displayed an exquisite "supersensitivity" to enantiomeric pairs of wine lactones and carvones. They were capable of supersensitive discrimination of enantiomers, consistent with their high detection sensitivity. In contrast, ΔD mice showed selective major loss of sensitivity to the (+)-enantiomers. The resulting 10(8)-fold differential sensitivity of ΔD mice to (-)- vs. (+)-wine lactone matched that observed in humans. This suggests that humans lack highly sensitive orthologous dorsal receptors for the (+)-enantiomer, similarly to ΔD mice. Moreover, ΔD mice showed >10(10)-fold reductions in enantiomer discrimination sensitivity compared to wild-type mice. ΔD mice detected one or both of the (-)- and (+)-enantiomers over a wide concentration range, but were unable to discriminate them. This "enantiomer odour discrimination paradox" indicates that the most sensitive dorsal receptors play a critical role in hierarchical odour coding for enantiomer identification.

  9. Inflammatory mediators potentiate high affinity GABA(A) currents in rat dorsal root ganglion neurons.

    Science.gov (United States)

    Lee, Kwan Yeop; Gold, Michael S

    2012-06-19

    Following acute tissue injury action potentials may be initiated in afferent processes terminating in the dorsal horn of the spinal cord that are propagated back out to the periphery, a process referred to as a dorsal root reflex (DRR). The DRR is dependent on the activation of GABA(A) receptors. The prevailing hypothesis is that DRR is due to a depolarizing shift in the chloride equilibrium potential (E(Cl)) following an injury-induced activation of the Na(+)-K(+)-Cl(-)-cotransporter. Because inflammatory mediators (IM), such as prostaglandin E(2) are also released in the spinal cord following tissue injury, as well as evidence that E(Cl) is already depolarized in primary afferents, an alternative hypothesis is that an IM-induced increase in GABA(A) receptor mediated current (I(GABA)) could underlie the injury-induced increase in DRR. To test this hypothesis, we explored the impact of IM (prostaglandin E(2) (1 μM), bradykinin (10 μM), and histamine (1 μM)) on I(GABA) in dissociated rat dorsal root ganglion (DRG) neurons with standard whole cell patch clamp techniques. IM potentiated I(GABA) in a subpopulation of medium to large diameter capsaicin insensitive DRG neurons. This effect was dependent on the concentration of GABA, manifest only at low concentrations (emergence of injury-induced DRR. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  10. Re-thinking the role of the dorsal striatum in egocentric/response strategy.

    Science.gov (United States)

    Botreau, Fanny; Gisquet-Verrier, Pascale

    2010-01-01

    Rats trained in a dual-solution cross-maze task, which can be solved by place and response strategies, predominantly used a response strategy after extensive training. This paper examines the involvement of the medial and lateral dorsal striatum (mDS and lDS) in the choice of these strategies after partial and extensive training. Our results show that rats with lDS and mDS lesions used mainly a response strategy from the early phase of training. We replicated these unexpected data in rats with lDS lesions and confirmed their tendency to use the response strategy in a modified cross-maze task. When trained in a dual-solution water-maze task, however, control and lesioned rats consistently used a place strategy, demonstrating that lDS and mDS lesioned rats can use a place strategy and that the shift towards a response strategy did not systematically result from extensive training. The present data did not show any clear dissociation between the mDS and lDS in dual solution tasks. They further indicate that the dorsal striatum seems to determine the strategies adopted in a particular context but cannot be considered as a neural support for the response memory system. Accordingly, the role of the lateral and medial part of the dorsal striatum in egocentric/response memory should be reconsidered.

  11. Complex population response of dorsal putamen neurons predicts the ability to learn.

    Science.gov (United States)

    Laquitaine, Steeve; Piron, Camille; Abellanas, David; Loewenstein, Yonatan; Boraud, Thomas

    2013-01-01

    Day-to-day variability in performance is a common experience. We investigated its neural correlate by studying learning behavior of monkeys in a two-alternative forced choice task, the two-armed bandit task. We found substantial session-to-session variability in the monkeys' learning behavior. Recording the activity of single dorsal putamen neurons we uncovered a dual function of this structure. It has been previously shown that a population of neurons in the DLP exhibits firing activity sensitive to the reward value of chosen actions. Here, we identify putative medium spiny neurons in the dorsal putamen that are cue-selective and whose activity builds up with learning. Remarkably we show that session-to-session changes in the size of this population and in the intensity with which this population encodes cue-selectivity is correlated with session-to-session changes in the ability to learn the task. Moreover, at the population level, dorsal putamen activity in the very beginning of the session is correlated with the performance at the end of the session, thus predicting whether the monkey will have a "good" or "bad" learning day. These results provide important insights on the neural basis of inter-temporal performance variability.

  12. Lmx1b-targeted cis-regulatory modules involved in limb dorsalization.

    Science.gov (United States)

    Haro, Endika; Watson, Billy A; Feenstra, Jennifer M; Tegeler, Luke; Pira, Charmaine U; Mohan, Subburaman; Oberg, Kerby C

    2017-06-01

    Lmx1b is a homeodomain transcription factor responsible for limb dorsalization. Despite striking double-ventral (loss-of-function) and double-dorsal (gain-of-function) limb phenotypes, no direct gene targets in the limb have been confirmed. To determine direct targets, we performed a chromatin immunoprecipitation against Lmx1b in mouse limbs at embryonic day 12.5 followed by next-generation sequencing (ChIP-seq). Nearly 84% ( n =617) of the Lmx1b-bound genomic intervals (LBIs) identified overlap with chromatin regulatory marks indicative of potential cis -regulatory modules (PCRMs). In addition, 73 LBIs mapped to CRMs that are known to be active during limb development. We compared Lmx1b-bound PCRMs with genes regulated by Lmx1b and found 292 PCRMs within 1 Mb of 254 Lmx1b-regulated genes. Gene ontological analysis suggests that Lmx1b targets extracellular matrix production, bone/joint formation, axonal guidance, vascular development, cell proliferation and cell movement. We validated the functional activity of a PCRM associated with joint-related Gdf5 that provides a mechanism for Lmx1b-mediated joint modification and a PCRM associated with Lmx1b that suggests a role in autoregulation. This is the first report to describe genome-wide Lmx1b binding during limb development, directly linking Lmx1b to targets that accomplish limb dorsalization. © 2017. Published by The Company of Biologists Ltd.

  13. The brain's dorsal route for speech represents word meaning: evidence from gesture.

    Science.gov (United States)

    Josse, Goulven; Joseph, Sabine; Bertasi, Eric; Giraud, Anne-Lise

    2012-01-01

    The dual-route model of speech processing includes a dorsal stream that maps auditory to motor features at the sublexical level rather than at the lexico-semantic level. However, the literature on gesture is an invitation to revise this model because it suggests that the premotor cortex of the dorsal route is a major site of lexico-semantic interaction. Here we investigated lexico-semantic mapping using word-gesture pairs that were either congruent or incongruent. Using fMRI-adaptation in 28 subjects, we found that temporo-parietal and premotor activity during auditory processing of single action words was modulated by the prior audiovisual context in which the words had been repeated. The BOLD signal was suppressed following repetition of the auditory word alone, and further suppressed following repetition of the word accompanied by a congruent gesture (e.g. ["grasp" + grasping gesture]). Conversely, repetition suppression was not observed when the same action word was accompanied by an incongruent gesture (e.g. ["grasp" + sprinkle]). We propose a simple model to explain these results: auditory and visual information converge onto premotor cortex where it is represented in a comparable format to determine (in)congruence between speech and gesture. This ability of the dorsal route to detect audiovisual semantic (in)congruence suggests that its function is not restricted to the sublexical level.

  14. Lag screw fixation of dorsal cortical stress fractures of the third metacarpal bone in 116 racehorses.

    Science.gov (United States)

    Jalim, S L; McIlwraith, C W; Goodman, N L; Anderson, G A

    2010-10-01

    The effectiveness and best method to manage dorsal cortical stress fractures is not clear. This study was performed to evaluate the success of lag screw fixation of such fractures in a population of Thoroughbred racehorses. Lag screw fixation of dorsal cortical stress fractures is an effective surgical procedure allowing racehorses to return to their preoperative level of performance. The records of 116 racehorses (103 Thoroughbreds) admitted to Equine Medical Centre, California between 1986 and 2008 were assessed. Information obtained from medical records included subject details, limb(s) affected, fracture configuration, length of screw used in repair and presence of concurrent surgical procedures performed. Racing performance was evaluated relative to these factors using Fisher's exact test and nonparametric methods with a level of significance of Phorses, 83% raced preoperatively and 83% raced post operatively, with 63% having ≥5 starts. There was no statistically significant association between age, gender, limb affected, fracture configuration or presence of concurrent surgery and likelihood of racing post operatively or of having 5 or more starts. The mean earnings per start and the performance index for the 3 races following surgery were lower compared to the 3 races prior to surgery; however, 29 and 45% of horses either improved or did not change their earnings per start and performance index, respectively. Data show that lag screw fixation is successful at restoring ability to race in horses suffering from dorsal cortical stress fractures. © 2010 EVJ Ltd.

  15. Incomplete oblique sagittal fractures of the dorsal cortex of the third metacarpal bone in six horses

    International Nuclear Information System (INIS)

    Watt, B.C.; Foerner, J.J.; Haines, G.R.

    1998-01-01

    To describe incomplete oblique sagittal dorsal cortical fractures of the equine third metacarpal bone, their surgical repair, and subsequent performance of the horses. Retrospective examination of medical records and racing performance. Six Thoroughbred race horses, 2 to 4 years of age. Radiographic confirmation of all fractures preceded general anesthesia and surgical correction. Three fractures were treated by intracortical compression using screws placed in lag fashion, and five fractures were treated by osteostixis. Race records were reviewed for each horse to determine performance after surgery. Fractures were best observed on palmarodorsal radiographic projections. Three horses treated by intracortical compression returned to racing, but fracture recurred in one horse and was treated by osteostixis. This horse and the other three horses treated by osteostixis raced after surgery. Horses with incomplete oblique sagittal fractures of the dorsal cortex of the third metacarpal bone can race after surgical management of the fracture by screws placed in lag fashion or osteostixis. The authors' preferred surgical procedure for managing this fracture is osteostixis. Palmarodorsal radiographic projections of the third metacarpal bone are recommended in young Thoroughbred race horses suspected of having dorsal metacarpal stress fractures

  16. Transarticular facet screw stabilization and dorsal laminectomy in 26 dogs with degenerative lumbosacral stenosis with instability.

    Science.gov (United States)

    Hankin, Elyshia J; Jerram, Richard M; Walker, Alexander M; King, Michael D; Warman, Christopher G A

    2012-07-01

    To describe outcome after transarticular facet screw stabilization and dorsal laminectomy for treatment of dynamic degenerative lumbosacral stenosis (DLS) in 26 dogs. Retrospective case series. Dogs (n = 26) with dynamic DLS. Medical records (2004-2009) of dogs treated with transarticular facet screw stabilization and dorsal laminectomy were reviewed. Dogs (n = 26) were available for immediate postoperative follow-up, 21 dogs at 6 weeks, and 15 at greater than 6 months. Dogs were evaluated by radiographic assessment and owner questionnaire. Lumbosacral (LS) intervertebral disc (IVD) spaces were measured on pre and postoperative 6-week and 6-month radiographs. In 23 dogs, improvement in clinical signs occurred within 7 days of surgery. Overall postsurgical complication rate directly related to the surgical procedure was 15.4%. LS IVD space measurements taken immediately postoperatively, at 6 weeks, and ≥ 6 months were all significantly increased compared with preoperative measurements. All working dogs (4) returned to full work within 14 months. Most owners (85%) reported their dog was ambulating normally at 6 months with no perceptible lameness during normal activity. All owners perceived their dog's ability to walk, run, and jump after surgery to be improved. Transarticular facet screw stabilization and dorsal laminectomy maintains distraction of the LS IVD space for medium-to-large breed dogs with dynamic DLS with a high degree of owner satisfaction, and is comparable to other reported surgical techniques for DLS. © Copyright 2012 by The American College of Veterinary Surgeons.

  17. Attention supports verbal short-term memory via competition between dorsal and ventral attention networks.

    Science.gov (United States)

    Majerus, Steve; Attout, Lucie; D'Argembeau, Arnaud; Degueldre, Christian; Fias, Wim; Maquet, Pierre; Martinez Perez, Trecy; Stawarczyk, David; Salmon, Eric; Van der Linden, Martial; Phillips, Christophe; Balteau, Evelyne

    2012-05-01

    Interactions between the neural correlates of short-term memory (STM) and attention have been actively studied in the visual STM domain but much less in the verbal STM domain. Here we show that the same attention mechanisms that have been shown to shape the neural networks of visual STM also shape those of verbal STM. Based on previous research in visual STM, we contrasted the involvement of a dorsal attention network centered on the intraparietal sulcus supporting task-related attention and a ventral attention network centered on the temporoparietal junction supporting stimulus-related attention. We observed that, with increasing STM load, the dorsal attention network was activated while the ventral attention network was deactivated, especially during early maintenance. Importantly, activation in the ventral attention network increased in response to task-irrelevant stimuli briefly presented during the maintenance phase of the STM trials but only during low-load STM conditions, which were associated with the lowest levels of activity in the dorsal attention network during encoding and early maintenance. By demonstrating a trade-off between task-related and stimulus-related attention networks during verbal STM, this study highlights the dynamics of attentional processes involved in verbal STM.

  18. Outcomes of Open Dorsal Wrist Ganglion Excision in Active-Duty Military Personnel.

    Science.gov (United States)

    Balazs, George C; Donohue, Michael A; Drake, Matthew L; Ipsen, Derek; Nanos, George P; Tintle, Scott M

    2015-09-01

    To examine the most common presenting complaints of active-duty service members with isolated dorsal wrist ganglions and to determine the rate of return to unrestricted duty after open excision. Surgical records at 2 military facilities were screened to identify male and female active duty service members undergoing isolated open excision of dorsal wrist ganglions from January 1, 2006 to January 1, 2014. Electronic medical records and service disability databases were searched to identify the most common presenting symptoms and to determine whether patients returned to unrestricted active duty after surgery. Postoperative outcomes examined were pain persisting greater than 4 weeks after surgery, stiffness requiring formal occupational therapy treatment, surgical wound complications, and recurrence. A total of 125 active duty military personnel (Army, 54; Navy, 43; and Marine Corps, 28) met criteria for inclusion. Mean follow-up was 45 months. Fifteen percent (8 of 54) of the Army personnel were given permanent waivers from performing push-ups owing to persistent pain and stiffness. Pain persisting greater than 4 weeks after surgery was an independent predictor of eventual need for a permanent push-up waiver. The overall recurrence incidence was 9%. No demographic or perioperative factors were associated with recurrence. Patients whose occupation or activities require forceful wrist extension should be counseled on the considerable risk of residual pain and functional limitations that may occur after open dorsal wrist ganglion excision. Therapeutic IV. Published by Elsevier Inc.

  19. Percutaneous dorsal closing wedge osteotomy of the metatarsal neck in management of metatarsalgia.

    Science.gov (United States)

    Lui, Tun Hing

    2014-12-01

    Metatarsalgia can be caused by plantarflexion of a central metatarsal or discrepancies in the metatarsals' length. Nonsurgical management is usually sufficient to achieve satisfactory results. For those recalcitrant cases, metatarsal osteotomy is needed to relieve the pain. We describe a technique of percutaneous dorsal closing wedge osteotomy of the metatarsal to manage the recalcitrant metatarsalgia. A case series was reviewed retrospectively. From March 2010 to March 2013, percutaneous dorsal closing wedge osteotomy of the metatarsal neck has been performed in 33 patients. Thirty six feet with 63 metatarsals were operated on. Thirty two second metatarsals, 22 third metatarsals, 5 fourth metatarsals and 4 fifth metatarsals were operated on. All the osteotomy sites healed up without any transverse plane deformity. The painful callosities subsided except in one operated metatarsal. Recurrence of painful callosities occurred in 2 operated metatarsals. Transfer metatarsalgia occurred in 2 feet. Floating toe deformity occurred in 2 operated rays. There was no nerve injury noted. Two patients had delayed wound healing with serous discharge and the wounds were eventually healed up with wound dressing. Percutaneous dorsal closing wedge osteotomy of the metatarsal neck is an effective and safe surgical treatment of recalcitrant metatarsalgia. Copyright © 2014 Elsevier Ltd. All rights reserved.

  20. The Onecut Transcription Factors Regulate Differentiation and Distribution of Dorsal Interneurons during Spinal Cord Development

    Directory of Open Access Journals (Sweden)

    Karolina U. Kabayiza

    2017-05-01

    Full Text Available During embryonic development, the dorsal spinal cord generates numerous interneuron populations eventually involved in motor circuits or in sensory networks that integrate and transmit sensory inputs from the periphery. The molecular mechanisms that regulate the specification of these multiple dorsal neuronal populations have been extensively characterized. In contrast, the factors that contribute to their diversification into smaller specialized subsets and those that control the specific distribution of each population in the developing spinal cord remain unknown. Here, we demonstrate that the Onecut transcription factors, namely Hepatocyte Nuclear Factor-6 (HNF-6 (or OC-1, OC-2 and OC-3, regulate the diversification and the distribution of spinal dorsal interneuron (dINs. Onecut proteins are dynamically and differentially distributed in spinal dINs during differentiation and migration. Analyzes of mutant embryos devoid of Onecut factors in the developing spinal cord evidenced a requirement in Onecut proteins for proper production of a specific subset of dI5 interneurons. In addition, the distribution of dI3, dI5 and dI6 interneuron populations was altered. Hence, Onecut transcription factors control genetic programs that contribute to the regulation of spinal dIN diversification and distribution during embryonic development.

  1. Histopathological evaluation of urethroplasty with dorsal buccal mucosa: an experimental study in rabbits

    Directory of Open Access Journals (Sweden)

    Geovanne F. Souza

    2008-06-01

    Full Text Available PURPOSE: Buccal mucosa is a widely accepted tissue for urethroplasty. The exact healing and tissue integration process, mainly the histological characteristics of dorsal buccal mucosa graft urethroplasty when used dorsally to reconstruct the urethral plate has not previously been assessed, and thus we developed an experimental model to address this question. MATERIALS AND METHODS: In 12 New Zealand rabbits (weight 2.5 kg we surgically created a dorsal penile urethral defect. A buccal mucosa graft was sutured to the corpora and tunica albuginea, and the ventral urethra anastomosed to this new urethral plate. The animals were divided in three groups and sacrificed 1, 3 and 6 weeks after surgery (groups 1, 2 and 3. A retrograde urethrogram was obtained at autopsy in the last group and the penis analyzed histologically with hematoxylin-eosin and Masson's staining. RESULTS: The urethrograms showed no evidence of fistula or stricture. In group 1 the histopathological analysis showed submucosal lymph-mononuclear inflammatory edema, numerous eosinophils and squamous epithelium integrated into the adjacent urothelium. In group 2 there was no evidence of an inflammatory response but rather complete subepithelial hyaline healing, which was more marked in group 3. CONCLUSION: Healing of buccal mucosa grafts to reconstruct the urethral plate can be achieved by total integration of the squamous epithelium with the urothelium, maintaining the original histological properties of the graft with no fibrosis or retraction.

  2. La superaci??n del modelo del ??ngel del hogar:

    OpenAIRE

    Hurtado Mu??oz, M??nica

    2012-01-01

    La Tesis Doctoral titulada "La superaci??n del modelo del "??ngel del hogar". Recuperaci??n de la escritora Leonor Canalejas y Fustegueras (1869-1945)" aborda, en primer lugar, un an??lisis sociol??gico de las circunstancias que rodearon a la mujer espa??ola en el cambio de siglo en el ??mbito social y educativo, en un intento de esclarecer las caracter??sticas propias del contexto en el que la mujer accede a la intelectualidad en general y a la literatura en particular. Esta parte concluye q...

  3. Inflammatory reaction of the anterior dorsal tongue presumably to sodium lauryl sulfate within toothpastes: a triple case report.

    Science.gov (United States)

    Brown, Ronald S; Smith, Langston; Glascoe, Alison L

    2018-02-01

    Sodium lauryl sulfate (SLS), a popular surface active agent ingredient within toothpastes, is known for its foaming action. Surface active agents increase the effectiveness of toothpastes with respect to dental plaque removal. SLS is a known irritant and also has allergenic potential. The authors report 3 patients with oral pain secondary to inflammation of the dorsal anterior tongue. These patients were all using toothpastes with SLS as an ingredient. The dorsal tongue lesions and oral pain resolved upon switching to toothpastes without SLS as an ingredient. Clinicians should be aware of the potential of SLS within toothpastes to cause oral mucosal inflammatory reactions of the anterior dorsal tongue. To our knowledge, these are the first case reports of oral mucosal inflammatory reactions of the anterior dorsal tongue associated with SLS containing toothpastes. Copyright © 2017 Elsevier Inc. All rights reserved.

  4. The first metatarsal web space: its applied anatomy and usage in tracing the first dorsal metatarsal artery in thumb reconstruction.

    Science.gov (United States)

    Xu, Yong-Qing; Li, Jun; Zhong, Shi-Zhen; Xu, Da-Chuan; Xu, Xiao-Shan; Guo, Yuan-Fa; Wang, Xin-Min; Li, Zhu-Yi; Zhu, Yue-Liang

    2004-12-01

    To clarify the anatomical relationship of the structures in the first toe webbing space for better dissection of toes in thumb reconstruction. The first dorsal metatarsal artery, the first deep transverse metatarsal ligament and the extensor expansion were observed on 42 adult cadaveric lower extremities. Clinically the method of tracing the first dorsal metatarsal artery around the space of the extensor expansion was used in 36 cases of thumb reconstruction. The distal segments of the first dorsal metatarsal artery of Gilbert types I and II were located superficially to the extensor expansion. The harvesting time of a toe was shortened from 90 minutes to 50 minutes with 100% survival of reconstructed fingers. The distal segment of the first dorsal metatarsal artery lies constantly at the superficial layer of the extensor expansion. Most of the first metatarsal arteries of Gilbert types I and II can be easily located via the combined sequential and reverse dissection around the space of the extensor expansion.

  5. Dorsal root potential produced by a TTX-insensitive micro-circuitry in the turtle spinal cord

    DEFF Research Database (Denmark)

    Russo, R E; Delgado-Lezama, R; Hounsgaard, J

    2000-01-01

    1, The mechanisms underlying the dorsal root potential (DRP) were studied in transverse slices of turtle spinal cord. DRPs were evoked by stimulating one filament in a dorsal root and were recorded from another such filament. 2. The DRP evoked at supramaximal stimulus intensity was reduced....... 5. Our results show that part of the DRP is generated by a TTX-resistant, probably non-spiking micro-circuit with separate components mediated by GABA and glutamate....

  6. Immunostaining for Homer reveals the majority of excitatory synapses in laminae I?III of the mouse spinal dorsal horn

    OpenAIRE

    Gutierrez-Mecinas, Maria; Kuehn, Emily D.; Abraira, Victoria E.; Polg?r, Erika; Watanabe, Masahiko; Todd, Andrew J.

    2016-01-01

    The spinal dorsal horn processes somatosensory information before conveying it to the brain. The neuronal organization of the dorsal horn is still poorly understood, although recent studies have defined several distinct populations among the interneurons, which account for most of its constituent neurons. All primary afferents, and the great majority of neurons in laminae I–III are glutamatergic, and a major factor limiting our understanding of the synaptic circuitry has been the difficulty i...

  7. Comparison of dorsal and dorsomedial displacement in evaluation of first ray hypermobility in feet with and without hallux valgus.

    Science.gov (United States)

    Singh, Dishan; Biz, Carlo; Corradin, Marco; Favero, Laura

    2016-06-01

    Hypermobility of the first ray, a probable primary cause of hallux valgus, has traditionally been evaluated in the dorsal direction only although the first tarso-metatarsal joint allows movement in a dorso-medial direction. 600 feet, divided according to the presence or absence of hallux valgus, were evaluated for both dorsal and dorso-medial displacement using a Klaue device. In the control group, the mean first ray displacement was 7.2mm (4.2-11.3) in the dorsal direction (sagittal plane) and 8.3mm (4.0-12.6) in the 45° dorso-medial direction. In the hallux valgus group, the mean first ray mobility was 9.8mm (5.2-14.1) in the dorsal direction compared to a mean of 11.0mm (5.9-16.2) in the 45° dorso-medial direction. It is a paradox that hypermobility of the first ray is measured in only a dorsal (vertical) direction whereas a hallux valgus angle and an intermetatarsal angle are only measured in a transverse plane. Furthermore, the weightbearing foot pronates during gait and the first metatarsal is displaced in a dorsomedial direction rather than a pure dorsal direction. It is suggested that measurement hypermobility of the first ray at a 45° dorso-medial direction is more appropriate. Copyright © 2015 European Foot and Ankle Society. Published by Elsevier Ltd. All rights reserved.

  8. Proyectos, Innovación y Estrategia (PIE. Un paso firme hacia nuevos modelos en la gestión empresarial

    Directory of Open Access Journals (Sweden)

    William Gutiérrez Sandí

    2011-05-01

    Full Text Available Los nuevos modelos económicos exigen a las organizaciones a responder de manera rápida a los diferentes cambios que generan los actores en los mercados. Este desequilibrio natural de los sistemas obligan a las organizaciones a variar su modelo estático para poder responder, de manera eficiente, a los cambios que se presentan. Ante un estado de cambio constante, la innovación debe ser la herramienta que permita enlazar las actividades estratégicas con las acciones operativas que son llevadas al campo práctico a través de la herramienta de los proyectos. Ese triángulo: Proyectos, Innovación y Estrategia, proporciona el soporte sobre el cual da los pasos la organización. Para poder enlazar dichas aristas se debe recurrir al uso de modelos de gestión, tecnología, destrezas y habilidades de comunicación interpersonal y empresarial. Por tanto, el PIE puede considerarse como un estándar en donde la Estrategia es el punto de partida; seguido por la Innovación como característica importante de la Estrategia, ya que constituye el medio o proceso para canalizar y desarrollar los productos de la estrategia; luego, finalmente, los Proyectos como herramienta para lograr los objetivos estratégicos innovadores planteados. Indispensable debe ser, ante cualquier acción a seguir, que las iniciativasimplementadas, las cuales se suman a la estrategia como eslabones de una cadena, representen un real aporte de valor en los cambios previstos por la organización.

  9. Una novela-testimonio dominicana sobre la dictadura de Trujillo : El Masacre se pasa a pie de Freddy Prestol Castillo

    Directory of Open Access Journals (Sweden)

    Lauro Capdevila

    2003-09-01

    Full Text Available El Masacre se pasa a pie de Freddy Prestol Castillo remporte un succès de librairie extraordinaire dès sa parution en 1973 et est rapidement considéré comme un classique, aujourd’hui étudié dans les établissements scolaires de la République Dominicaine. Dans ce roman-témoignage – pour reprendre la terme proposé par Miguel Barnet, l’auteur rapporte à la première personne le massacre de 12 000 à 20 000 présumés Haïtiens par les hommes de main du Trujillo en 1937. L’événement est un des moments décisifs de la dictature : il en marque profondément le caractère raciste et sanctionne les relations de violence entre l’État et la population. Dénonciatrice, l’œuvre cherche à rétablir la vérité des faits contre les mensonges de la propagande officielle. Nourri par cette volonté d’authenticité, le roman présente de façon dynamique et synthétique les bouleversements que subit la société dominicaine soumise à l’État dictatorial. La littérature apparaît ici comme une urgente nécessité pour restituer sa mémoire à la nation dans la perspective de sa reconstruction.El Masacre se pasa a pie de Freddy Prestol Castillo es un extraordinario éxito de ventas al publicarse en 1973. Muy pronto pasa a ser una obra clásica, estudiada hoy en los centros de enseñanza de la República Dominicana. En esa novela-testimonio – para usar el término propuesto por el cubano Miguel Barnet, el autor relata en primera persona la matanza de 12.000 a 20.000 presuntos haitianos a manos de los esbirros de Trujillo en 1937. El trágico acontecimiento es uno de los momentos álgidos de la dictadura que manifiesta claramente su carácter racista y deja al desnudo las relaciones de violencia entre el Estado y la población. Denunciadora, la obra pretende restablecer los hechos verídicos contra las mentiras de la propaganda oficial. Apoyándose en esta voluntad de autenticidad, la novela presenta de modo dinámico y sint

  10. Actividades fisicas para el tratamiento de la obesidad en mujeres de 40 - 50 años de la comunidad 5 de septiembre del municipio de Pinar del Rio, en Cuba

    Directory of Open Access Journals (Sweden)

    Nancy Rodríguez Cabrera

    2009-06-01

    Full Text Available Nuestra investigación esta encaminada a la aplicación de un tratamiento físico del peso corporal en las mujeres obesas del consultorio 21 del Rpto. 5 de Septiembre del municipio Pinar del Río. Los ejercicios en las personas obesas son de gran importancia, puesto que conllevan a la disminución del peso corporal excesivo, sin dejar pasar por alto la dieta, que también contribuye al tratamiento de esta patología. Para ello aplicamos ejercicios con carácter aerobio de intensidad moderada tomando en cuenta la distribución topográfica en un período de un año. Se realizaron dos mediciones, un primero que nos permitió conocer el peso y estructura corporal de cada una de las muestras. Para ello tuvimos en cuenta el peso ideal, adecuado a la distribución topográfica a partir del índice cintura – cadera y se registró la talla o estatura de pie para el cálculo de IMC, estos datos permiten conocer el peso de la muestra, y su clasificación o grado de obesidad. Para la realización de nuestro trabajo utilizamos métodos teóricos y empíricos y como procedimiento estadístico empleamos el análisis porcentual, pudimos constatar  la  efectividad  de  la  aplicación  práctica  del  ejercicio  físico,  pues disminuyó el peso corporal de nuestros practicantes, acercándole cada vez más a su peso ideal.

  11. CONSEQÜÊNCIAS DA LAMINECTOMIA DORSAL DO TIPO FUNKQUIST A EM CÃES NORMAIS CONSEQUENCES OF THE FUNKQUIST A DORSAL LAMINECTOMY, IN NORMAL DOGS

    Directory of Open Access Journals (Sweden)

    Eduardo Alberto Tudury

    2001-02-01

    Full Text Available O objetivo desta pesquisa foi verificar os efeitos da laminectomia dorsal do tipo Funkquist A em cães normais. A técnica realizada consistiu em abordagem dorsal à coluna vertebral; remoção (com ou sem a ajuda da elevação dos corpos vertebrais das lâminas dorsais de T13 e L1; manutenção do ligamento supra-espinhal; colocação de gordura subcutânea como coxim supramedular; sutura da fáscia toracolombar, subcutâneo e pele; e bandagem compressiva por sete dias. Quarenta e oito horas após a cirurgia, todos os 10 cães submetidos a essa técnica exibiram perda das reações posturais e paresia de moderada a grave nos membros pélvicos. Hipoalgesia foi constatada em cinco deles. Tentando descobrir as causas, foram realizados estudos histológicos de medulas espinhais, coletadas 4 e 48 horas após a realização da laminectomia, porém com modificações como: não elevação dos corpos vertebrais durante a cirurgia e prevenção de qualquer tipo de compressão medular após a laminectomia. Analisando esses resultados, foi possível concluir que as disfunções neurológicas decorreram de lesões medulares ocasionadas possivelmente por: elevações dos corpos vertebrais durante a laminectomia, danificação de vasos espinhais, desestabilização da coluna vertebral e uma somatória de forças compressivas atuantes sobre a medula espinhal desprotegida. Na necropsia de cinco cães, acompanhados por quarenta e cinco dias, foi possível constatar: a permanência do ligamento supra-espinhal; que o enxerto de gordura não evita a penetração do tecido fibroso no canal vertebral nem sua aderência à dura- máter; notório (PThe purpose of this research was to check the effects of the Funkquist A dorsal laminectomy in normal dogs. The technique accomplished consisted in dorsal approach to the spine; removal of T13-L1 laminae with or without vertebral bodies elevation; mantainement of the supraspinous ligament; placement of subcutaneous fat as

  12. Emotional detachment in psychopathy: Involvement of dorsal default-mode connections.

    Science.gov (United States)

    Sethi, Arjun; Gregory, Sarah; Dell'Acqua, Flavio; Periche Thomas, Eva; Simmons, Andy; Murphy, Declan G M; Hodgins, Sheilagh; Blackwood, Nigel J; Craig, Michael C

    2015-01-01

    Criminal psychopathy is defined by emotional detachment [Psychopathy Checklist - Revised (PCL-R) factor 1], and antisocial behaviour (PCL-R factor 2). Previous work has associated antisocial behaviour in psychopathy with abnormalities in a ventral temporo-amygdala-orbitofrontal network. However, little is known of the neural correlates of emotional detachment. Imaging studies have indicated that the 'default-mode network' (DMN), and in particular its dorsomedial (medial prefrontal - posterior cingulate) component, contributes to affective and social processing in healthy individuals. Furthermore, recent work suggests that this network may be implicated in psychopathy. However, no research has examined the relationship between psychopathy, emotional detachment, and the white matter underpinning the DMN. We therefore used diffusion tensor imaging (DTI) tractography in 13 offenders with psychopathy and 13 non-offenders to investigate the relationship between emotional detachment and the microstructure of white matter connections within the DMN. These included the dorsal cingulum (containing the medial prefrontal - posterior cingulate connections of the DMN), and the ventral cingulum (containing the posterior cingulate - medial temporal connections of the DMN). We found that fractional anisotropy (FA) was reduced in the left dorsal cingulum in the psychopathy group (p = .024). Moreover, within this group, emotional detachment was negatively correlated with FA in this tract portion bilaterally (left: r = -.61, p = .026; right: r = -.62, p = .023). These results suggest the importance of the dorsal DMN in the emotional detachment observed in individuals with psychopathy. We propose a 'dual-network' model of white matter abnormalities in the disorder, which incorporates these with previous findings. Copyright © 2014 Elsevier Ltd. All rights reserved.

  13. Enhanced inhibitory synaptic transmission in the spinal dorsal horn mediates antinociceptive effects of TC-2559

    Science.gov (United States)

    2011-01-01

    Background TC-2559 is a selective α4β2 subtype of nicotinic acetylcholine receptor (nAChR) partial agonist and α4β2 nAChR activation has been related to antinociception. The aim of this study is to investigate the analgesic effect of TC-2559 and its underlying spinal mechanisms. Results 1) In vivo bioavailability study: TC-2559 (3 mg/kg) had high absorption rate in rats with maximal total brain concentration reached over 4.6 μM within first 15 min after administration and eliminated rapidly with brain half life of about 20 min after injection. 2) In vivo behavioral experiments: TC-2559 exerts dose dependent antinociceptive effects in both formalin test in mice and chronic constriction injury (CCI) model in rats by activation of α4β2 nAChRs; 3) Whole-cell patch-clamp studies in the superficial dorsal horn neurons of the spinal cord slices: perfusion of TC-2559 (2 μM) significantly increased the frequency, but not amplitude of spontaneous inhibitory postsynaptic currents (sIPSCs). The enhancement of sIPSCs was blocked by pre-application of DHβE (2 μM), a selective α4β2 nicotinic receptor antagonist. Neither the frequency nor the amplitude of spontaneous excitatory postsynaptic currents (sEPSCs) of spinal dorsal horn neurons were affected by TC-2559. Conclusions Enhancement of inhibitory synaptic transmission in the spinal dorsal horn via activation of α4β2 nAChRs may be one of the mechanisms of the antinociceptive effects of TC-2559 on pathological pain models. It provides further evidence to support the notion that selective α4β2 subtype nAChR agonist may be developed as new analgesic drug for the treatment of neuropathic pain. PMID:21816108

  14. Preferential loss of dorsal-hippocampus synapses underlies memory impairments provoked by short, multimodal stress.

    Science.gov (United States)

    Maras, P M; Molet, J; Chen, Y; Rice, C; Ji, S G; Solodkin, A; Baram, T Z

    2014-07-01

    The cognitive effects of stress are profound, yet it is unknown if the consequences of concurrent multiple stresses on learning and memory differ from those of a single stress of equal intensity and duration. We compared the effects on hippocampus-dependent memory of concurrent, hours-long light, loud noise, jostling and restraint (multimodal stress) with those of restraint or of loud noise alone. We then examined if differences in memory impairment following these two stress types might derive from their differential impact on hippocampal synapses, distinguishing dorsal and ventral hippocampus. Mice exposed to hours-long restraint or loud noise were modestly or minimally impaired in novel object recognition, whereas similar-duration multimodal stress provoked severe deficits. Differences in memory were not explained by differences in plasma corticosterone levels or numbers of Fos-labeled neurons in stress-sensitive hypothalamic neurons. However, although synapses in hippocampal CA3 were impacted by both restraint and multimodal stress, multimodal stress alone reduced synapse numbers severely in dorsal CA1, a region crucial for hippocampus-dependent memory. Ventral CA1 synapses were not significantly affected by either stress modality. Probing the basis of the preferential loss of dorsal synapses after multimodal stress, we found differential patterns of neuronal activation by the two stress types. Cross-correlation matrices, reflecting functional connectivity among activated regions, demonstrated that multimodal stress reduced hippocampal correlations with septum and thalamus and increased correlations with amygdala and BST. Thus, despite similar effects on plasma corticosterone and on hypothalamic stress-sensitive cells, multimodal and restraint stress differ in their activation of brain networks and in their impact on hippocampal synapses. Both of these processes might contribute to amplified memory impairments following short, multimodal stress.

  15. Intracellular responses to frequency modulated tones in the dorsal cortex of the mouse inferior colliculus

    Directory of Open Access Journals (Sweden)

    Ruediger eGeis

    2013-01-01

    Full Text Available Frequency modulations occur in many natural sounds, including vocalizations. The neuronal response to frequency modulated (FM stimuli has been studied extensively in different brain areas, with an emphasis on the auditory cortex and the central nucleus of the inferior colliculus. Here, we measured the responses to FM sweeps in whole-cell recordings from neurons in the dorsal cortex of the mouse inferior colliculus. Both up- and downward logarithmic FM sweeps were presented at two different speeds to both the ipsi- and the contralateral ear. Based on the number of action potentials that were fired, between 10-24% of cells were selective for rate or direction of the FM sweeps. A somewhat lower percentage of cells, 6-21%, showed selectivity based on EPSP size. To study the mechanisms underlying the generation of FM selectivity, we compared FM responses with responses to simple tones in the same cells. We found that if pairs of neurons responded in a similar way to simple tones, they generally also responded in a similar way to FM sweeps. Further evidence that FM selectivity can be generated within the dorsal cortex was obtained by reconstructing FM sweeps from the response to simple tones using three different models. In about half of the direction selective neurons the selectivity was generated by spectrally asymmetric synaptic inhibition. In addition, evidence for direction selectivity based on the timing of excitatory responses was also obtained in some cells. No clear evidence for the local generation of rate selectivity was obtained. We conclude that FM direction selectivity can be generated within the dorsal cortex of the mouse inferior colliculus by multiple mechanisms.

  16. Preputial skin free graft as dorsal onlay urethroplasty: Our experience of 73 patients

    Directory of Open Access Journals (Sweden)

    Shivadeo S Bapat

    2007-01-01

    Full Text Available Objective: To present the outcome of dorsal onlay urethroplasty in 73 patients for stricture urethra over a period of eight years. Materials and Methods: Seventy-three patients of stricture urethra have undergone dorsal onlay urethroplasty from July 1998 to February 2006. Age distribution: 14-58 years. Etiology: Trauma 20/73 (27.39%, Balanitis Xerotica Obliterans 2/73 (2.73%, Iatrogenic 26/73(35.61%, Infection 3/73 (4.10%, Idiopathic 22/73 (30.13%. Site: Penobulbar-25/73, bulbar-38/73, membranous-8/73 and long length-2/73. Suprapubic catheter was inserted preoperatively: 21/73 patients. Preputial / distal penile skin was used in all patients. Buccal mucosa was not used in any patient. Hospitalization was for four to five days. Catheter was removed after 21 days. All patients had their first endoscopic checkup after three months. Subsequently they were followed up by uroflometry. Routine imaging of urethra for follow-up was not carried out. Results: 63/73 (86.30% patients had satisfactory outcome not requiring any further treatment, 8/73 (10.95% developed anastomotic stricture (3/8-optical internal urethrotomy, 5/8 dilatation alone. 2/73 (2.75% developed external meatal stenosis. None had urinary fistula and required repeat urethroplasty. Follow-up ranged from three months to eight years. Conclusion: Dorsal onlay urethroplasty using preputial/distal penile skin is a satisfactory procedure. Preputial/distal penile skin is devoid of hair and fat and hence an ideal graft material. Even in circumscribed patients distal penile skin can be harvested. Long-term follow-up is required in judging results of patients with stricture urethra.

  17. Preputial skin free graft as dorsal onlay urethroplasty: Our experience of 73 patients.

    Science.gov (United States)

    Bapat, Shivadeo S; Padhye, Abhijit S; Yadav, Pushkaraj B; Bhave, Ashish A

    2007-10-01

    To present the outcome of dorsal onlay urethroplasty in 73 patients for stricture urethra over a period of eight years. Seventy-three patients of stricture urethra have undergone dorsal onlay urethroplasty from July 1998 to February 2006. Age distribution: 14-58 years. Trauma 20/73 (27.39%), Balanitis Xerotica Obliterans 2/73 (2.73%), Iatrogenic 26/73(35.61%), Infection 3/73 (4.10%), Idiopathic 22/73 (30.13%). Site: Penobulbar-25/73, bulbar-38/73, membranous-8/73 and long length-2/73. Suprapubic catheter was inserted preoperatively: 21/73 patients. Preputial / distal penile skin was used in all patients. Buccal mucosa was not used in any patient. Hospitalization was for four to five days. Catheter was removed after 21 days. All patients had their first endoscopic checkup after three months. Subsequently they were followed up by uroflometry. Routine imaging of urethra for follow-up was not carried out. 63/73 (86.30%) patients had satisfactory outcome not requiring any further treatment, 8/73 (10.95%) developed anastomotic stricture (3/8-optical internal urethrotomy, 5/8 dilatation alone). 2/73 (2.75%) developed external meatal stenosis. None had urinary fistula and required repeat urethroplasty. Follow-up ranged from three months to eight years. Dorsal onlay urethroplasty using preputial/distal penile skin is a satisfactory procedure. Preputial/distal penile skin is devoid of hair and fat and hence an ideal graft material. Even in circumscribed patients distal penile skin can be harvested. Long-term follow-up is required in judging results of patients with stricture urethra.

  18. The influence of cannabinoids on learning and memory processes of the dorsal striatum.

    Science.gov (United States)

    Goodman, Jarid; Packard, Mark G

    2015-11-01

    Extensive evidence indicates that the mammalian endocannabinoid system plays an integral role in learning and memory. Our understanding of how cannabinoids influence memory comes predominantly from studies examining cognitive and emotional memory systems mediated by the hippocampus and amygdala, respectively. However, recent evidence suggests that cannabinoids also affect habit or stimulus-response (S-R) memory mediated by the dorsal striatum. Studies implementing a variety of maze tasks in rats indicate that systemic or intra-dorsolateral striatum infusions of cannabinoid receptor agonists or antagonists impair habit memory. In mice, cannabinoid 1 (CB1) receptor knockdown can enhance or impair habit formation, whereas Δ(9)THC tolerance enhances habit formation. Studies in human cannabis users also suggest an enhancement of S-R/habit memory. A tentative conclusion based on the available data is that acute disruption of the endocannabinoid system with either agonists or antagonists impairs, whereas chronic cannabinoid exposure enhances, dorsal striatum-dependent S-R/habit memory. CB1 receptors are required for multiple forms of striatal synaptic plasticity implicated in memory, including short-term and long-term depression. Interactions with the hippocampus-dependent memory system may also have a role in some of the observed effects of cannabinoids on habit memory. The impairing effect often observed with acute cannabinoid administration argues for cannabinoid-based treatments for human psychopathologies associated with a dysfunctional habit memory system (e.g. post-traumatic stress disorder and drug addiction/relapse). In addition, the enhancing effect of repeated cannabinoid exposure on habit memory suggests a novel neurobehavioral mechanism for marijuana addiction involving the dorsal striatum-dependent memory system. Copyright © 2015 Elsevier Inc. All rights reserved.

  19. A Way to Avoid Muscular Fibrosis in the First Dorsal Interosseous Muscle after Acupuncture Injection Therapy

    Directory of Open Access Journals (Sweden)

    Yiu Ming Wong

    2017-09-01

    Full Text Available Fibrosis of skeletal muscle following acupuncture is an iatrogenic disorder. The present case illustrates a patient with a unilateral fibrotic formation on a thumb muscle after acupuncture injection therapy with red sage. The patient in the present case was a counter-terrorism police officer with right-handedness; he noted a palpable nodule three months after injection therapy at his left first dorsal interosseous in which the acupuncture point LI4 (He Gu is located. He also found a reduction in the strength of his left pinch grip that noticeably affected his left handgun marksmanship. However, being ambidextrous in single-hand pistol shooting is an essential requirement for counter-terrorism police officers. Based on the patient’s medical history and claims, no underlying disease or trauma was found to be associated with his current complaint. During physical examination, a fibrotic formation in his left first dorsal interosseous muscle was visualized by using diagnostic ultrasound; also, as confirmed with dynamometry, the strength of his left pinch grip was significantly lower than that of the right counterpart. Because acupuncture injection therapy has three components, antiseptic practices, the mechanical action of syringe insertion, and the pharmacological effect of the sterile herb extract, any one of the components may have contributed to the present adverse event. The first dorsal interosseous muscle is small in dimension and rather vascular; thus, it is not an ideal site for intramuscular injection. When a clinician needs to treat a patient by performing acupuncture at the LI4 acupoint and injecting a herbal extract simultaneously, the clinician should only mechanically stimulate the LI4 acupoint while injecting the herbal medicine into the LI14 (Bi Noe acupoint on the same meridian, the LI14 acupoint being located in the distal portion of the deltoid muscle and being fairly close to the universally agreed upon site on the upper arm

  20. Inhibitory coupling between inhibitory interneurons in the spinal cord dorsal horn

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    Ribeiro-da-Silva Alfredo

    2009-05-01

    Full Text Available Abstract Local inhibitory interneurons in the dorsal horn play an important role in the control of excitability at the segmental level and thus determine how nociceptive information is relayed to higher structures. Regulation of inhibitory interneuron activity may therefore have critical consequences on pain perception. Indeed, disinhibition of dorsal horn neuronal networks disrupts the balance between excitation and inhibition and is believed to be a key mechanism underlying different forms of pain hypersensitivity and chronic pain states. In this context, studying the source and the synaptic properties of the inhibitory inputs that the inhibitory interneurons receive is important in order to predict the impact of drug action at the network level. To address this, we studied inhibitory synaptic transmission in lamina II inhibitory interneurons identified under visual guidance in spinal slices taken from transgenic mice expressing enhanced green fluorescent protein (EGFP under the control of the GAD promoter. The majority of these cells fired tonically to a long depolarizing current pulse. Monosynaptically evoked inhibitory postsynaptic currents (eIPSCs in these cells were mediated by both GABAA and glycine receptors. Consistent with this, both GABAA and glycine receptor-mediated miniature IPSCs were recorded in all of the cells. These inhibitory inputs originated at least in part from local lamina II interneurons as verified by simultaneous recordings from pairs of EGFP+ cells. These synapses appeared to have low release probability and displayed potentiation and asynchronous release upon repeated activation. In summary, we report on a previously unexamined component of the dorsal horn circuitry that likely constitutes an essential element of the fine tuning of nociception.