WorldWideScience

Sample records for domain eastern region

  1. Regional Development of Eastern Slovakia

    Directory of Open Access Journals (Sweden)

    Monika Hergezelová

    2017-08-01

    Full Text Available Purpose and Originality: The aim of the work is to provide an overview of regional development in Eastern Slovakia, where are Košice and Prešov Region. The originality of the work lies in the work of enriching the SWOT analysis from the author Eve Rajčáková, which is given in the book deals with the issue of Regional development and regional policy of the European Union and Slovakia. Research question: The conditions of life of people in eastern Slovakia. Method: For writing this contribution will be used method of analysis and statistics. Knowledge on this subject have been looking on the internet and in books and sources of information publicly available. Using the data collected, we dealt with the issue of regional development in the Košice and Prešov regions. Results: The topic was the beginning focused on the overall characteristics of eastern Slovakia. Furthermore, we are at work we dealt with social and economic phenomena in both regions of eastern Slovakia. We focused on GDP, unemployment and tourism, which is in the region is widespread. Society: It is well known that there are obviously different living conditions in eastern Slovakia as in other parts of Slovakia. People are forced to, mainly because of employment, leave their region to move or commute to work to the west. The paper point out the right of this negative phenomenon that is quite visible - high unemployment. Limitations: The limits of work are limited by problems of regional development in eastern Slovakia, mainly focusing on economic and social phenomena in the society.

  2. Eastern Baltic Sea Region

    DEFF Research Database (Denmark)

    Jakobsen, Johnny Grandjean Gøgsig

    2016-01-01

    Kort over den østlige Østersøregion i middelalderen med angivelse af lokaliteter omtalt i antologien, placeret på s.8 i bogen "Church and Belief in the Middle Ages", red. Kirsi Salonen & Sari Katajala-Peltomaa (Amsterdam, 2016).......Kort over den østlige Østersøregion i middelalderen med angivelse af lokaliteter omtalt i antologien, placeret på s.8 i bogen "Church and Belief in the Middle Ages", red. Kirsi Salonen & Sari Katajala-Peltomaa (Amsterdam, 2016)....

  3. Astroparticle physics at the Eastern Colombia region

    Science.gov (United States)

    Asorey, Hernán; Núñez, Luis A.

    2015-12-01

    We present the emerging panorama of Astroparticle Physics at the Eastern Colombia region, and describe several ongoing projects, most of them related to the Latin American Giant Observatory (LAGO) Project. This research work is carried out at the Grupo de Investigaciones en Relatividad y Gravitacin of Universidad Industrial de Santander.

  4. Regional climate model sensitivity to domain size

    Science.gov (United States)

    Leduc, Martin; Laprise, René

    2009-05-01

    Regional climate models are increasingly used to add small-scale features that are not present in their lateral boundary conditions (LBC). It is well known that the limited area over which a model is integrated must be large enough to allow the full development of small-scale features. On the other hand, integrations on very large domains have shown important departures from the driving data, unless large scale nudging is applied. The issue of domain size is studied here by using the “perfect model” approach. This method consists first of generating a high-resolution climatic simulation, nicknamed big brother (BB), over a large domain of integration. The next step is to degrade this dataset with a low-pass filter emulating the usual coarse-resolution LBC. The filtered nesting data (FBB) are hence used to drive a set of four simulations (LBs for Little Brothers), with the same model, but on progressively smaller domain sizes. The LB statistics for a climate sample of four winter months are compared with BB over a common region. The time average (stationary) and transient-eddy standard deviation patterns of the LB atmospheric fields generally improve in terms of spatial correlation with the reference (BB) when domain gets smaller. The extraction of the small-scale features by using a spectral filter allows detecting important underestimations of the transient-eddy variability in the vicinity of the inflow boundary, which can penalize the use of small domains (less than 100 × 100 grid points). The permanent “spatial spin-up” corresponds to the characteristic distance that the large-scale flow needs to travel before developing small-scale features. The spin-up distance tends to grow in size at higher levels in the atmosphere.

  5. Regional climate model sensitivity to domain size

    Energy Technology Data Exchange (ETDEWEB)

    Leduc, Martin [Universite du Quebec a Montreal, Canadian Regional Climate Modelling and Diagnostics (CRCMD) Network, ESCER Centre, Montreal (Canada); UQAM/Ouranos, Montreal, QC (Canada); Laprise, Rene [Universite du Quebec a Montreal, Canadian Regional Climate Modelling and Diagnostics (CRCMD) Network, ESCER Centre, Montreal (Canada)

    2009-05-15

    Regional climate models are increasingly used to add small-scale features that are not present in their lateral boundary conditions (LBC). It is well known that the limited area over which a model is integrated must be large enough to allow the full development of small-scale features. On the other hand, integrations on very large domains have shown important departures from the driving data, unless large scale nudging is applied. The issue of domain size is studied here by using the ''perfect model'' approach. This method consists first of generating a high-resolution climatic simulation, nicknamed big brother (BB), over a large domain of integration. The next step is to degrade this dataset with a low-pass filter emulating the usual coarse-resolution LBC. The filtered nesting data (FBB) are hence used to drive a set of four simulations (LBs for Little Brothers), with the same model, but on progressively smaller domain sizes. The LB statistics for a climate sample of four winter months are compared with BB over a common region. The time average (stationary) and transient-eddy standard deviation patterns of the LB atmospheric fields generally improve in terms of spatial correlation with the reference (BB) when domain gets smaller. The extraction of the small-scale features by using a spectral filter allows detecting important underestimations of the transient-eddy variability in the vicinity of the inflow boundary, which can penalize the use of small domains (less than 100 x 100 grid points). The permanent ''spatial spin-up'' corresponds to the characteristic distance that the large-scale flow needs to travel before developing small-scale features. The spin-up distance tends to grow in size at higher levels in the atmosphere. (orig.)

  6. Regional Wave Climates along Eastern Boundary Currents

    Science.gov (United States)

    Semedo, Alvaro; Soares, Pedro

    2016-04-01

    Two types of wind-generated gravity waves coexist at the ocean surface: wind sea and swell. Wind sea waves are waves under growing process. These young growing waves receive energy from the overlaying wind and are strongly coupled to the local wind field. Waves that propagate away from their generation area and no longer receive energy input from the local wind are called swell. Swell waves can travel long distances across entire ocean basins. A qualitative study of the ocean waves from a locally vs. remotely generation perspective is important, since the air sea interaction processes is strongly modulated by waves and vary accordingly to the prevalence of wind sea or swell waves in the area. A detailed climatology of wind sea and swell waves along eastern boundary currents (EBC; California Current, Canary Current, in the Northern Hemisphere, and Humboldt Current, Benguela Current, and Western Australia Current, in the Southern Hemisphere), based on the ECMWF (European Centre for Medium-Range Weather Forecasts) ERA-Interim reanalysis will be presented. The wind regime along EBC varies significantly from winter to summer. The high summer wind speeds along EBC generate higher locally generated wind sea waves, whereas lower winter wind speeds in these areas, along with stronger winter extratropical storms far away, lead to a predominance of swell waves there. In summer, the coast parallel winds also interact with coastal headlands, increasing the wind speed through a process called "expansion fan", which leads to an increase in the height of locally generated waves downwind of capes and points. Hence the spatial patterns of the wind sea or swell regional wave fields are shown to be different from the open ocean along EBC, due to coastal geometry and fetch dimensions. Swell waves will be shown to be considerably more prevalent and to carry more energy in winter along EBC, while in summer locally generated wind sea waves are either more comparable to swell waves or

  7. Secondary School Admissions Policies in Eastern Africa: Some Regional Issues

    Science.gov (United States)

    Gould, W. T. S.

    1974-01-01

    This discussion considers some regional issues implicit in current procedures regulating admission to secondary education in four countries of Eastern Africa and places these procedures in their general political context. (Author)

  8. Prospects of Collective Security in the Eastern Africa Region

    Science.gov (United States)

    2013-06-14

    Union EAC East African Community EAR Eastern Africa Region EASBRIG East African Standby Brigade EASF Eastern Africa Standby Force ECOMOG ECOWAS...address inherent social, economic and political problems while at the same time facing the world economy as one block (AU 2000). The Union is a...the East African Community ( EAC ) will go on smoothly and its success will continue to attract other regional states to join thereby expanding the

  9. Fuel shortage hits eastern Siberia region

    International Nuclear Information System (INIS)

    Land, R.

    1992-01-01

    Moscow's loss of absolute authority over the Russian economy has contributed to growing chaos in the supply of oil and gas to the former U.S.S.R.'s far eastern territories. This paper reports that Sakhalin Island, which has provided a substantial portion of the area's hydrocarbon fuels, has shown increasing reluctance to sell oil and gas for nearly worthless rubles to its eastern Siberian neighbors. Instead, it is bartering as much as possible of its surplus petroleum for foreign food and consumer goods. Moscow's Izvestia newspaper strongly criticized Sakhalin authorities for placing the island's interests ahead of the welfare of the Russian republic as a whole. It the Sakhalin's selfish attitude resulted in near disaster last winter for the economy and populace of neighboring Khabarovsk territory on the Siberian mainland. Only milder than normal winter weather prevented a catastrophe, Izvestia reported. Even so, some old people died from the cold in Khabarovsk, a city of 600,000 population

  10. REGIONALIZATION IN EASTERN AND CENTRAL EUROPE: OBSTACLES AND PERSPECTIVES

    Directory of Open Access Journals (Sweden)

    Gyula Horváth

    2012-01-01

    Full Text Available Regional policy depends on efficient administrative systems for designing and implementing strategies, and places considerable demands on Member States’ public administrations in terms of e.g. financial management and monitoring; project selection procedures; ex ante environmental impact assessments and cost-benefit analyses; and the monitoring and evaluation of outputs, results and impacts. EU member states have taken a range of different approaches to the administration of regional policy.The construction of regions in the countries of Eastern and Central Europe became one of the important debate topics for preparation for EU membership. Despite the numerous similarities in the changes that have taken place in the territorial structures of the Eastern and Central European countries, the differences in the responses individual countries gave to the challenges of regional development and the varied results of their development efforts demonstrate that the “Eastern European Bloc” is at least as heterogeneous as the former member states of the European Union. EU accession opened up a Pandora’s Box in the countries of Eastern and Central Europe. The fundamental issue of how unitarily structured states can be set on a decentralised path became the centre of debate. The paper introduces the Central and Eastern European achievements of region building processes and searches for an explanation of the reasons for the difficulties of Eastern and Central Europe in regional construction; it summarises the administrative and political development pre-requisites of the transition to a regional outline of the possible advantages of a regional institutional system in the creation of the Cohesion Policy ensuring a decrease in regional differences.

  11. ( Mangifera indica L.) in Harari Regional State, Eastern Ethiopia

    African Journals Online (AJOL)

    Mango production covers 35% of the total acreage allotted for fruit production in Harari Regional State, eastern Ethiopia. However, there is a declining trend in yield and quality of fruits from the trees. Therefore, this study was conducted to assess the status, practices and challenges of mango production in the study area.

  12. Redefining Maritime Security Threats in the Eastern Indian Ocean Region.

    Energy Technology Data Exchange (ETDEWEB)

    Banerjee, Arjun [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-08-01

    This occasional paper analyzes the general security issues and trends relating to maritime trafficking of radiological and nuclear material using small vessels, minor ports, and unchecked areas of coastline existing in the Eastern Indian Ocean Region today. By the Eastern Indian Ocean Region is meant the area starting from the tip of the Indian peninsula in the west to the Straits of Malacca in the east. It lays focus on the potential sources of nuclear or radiological material that may be trafficked here. It further undertakes a study of the terrorist groups active in the region as well as the multinational or national interdiction organizations that have been created to counter maritime threats. It also seeks to discern the various technologies for detecting materials of concern available in the area. Finally, it ascertains possible methods and technologies to improve the maritime security system in the region.

  13. Regionalization of Crustal and Upper Mantle Q Structure in Eastern Eurasia Using Multiple Regional Waves

    National Research Council Canada - National Science Library

    Gaherty, James; Lerner-Lam, Arthur

    2007-01-01

    We have mapped lateral variations in seismic Q in eastern Eurasia, including continental China, central Asia, Mongolia and Siberia, using high-frequency regional phases Lg and Pn, as well as long-period Rayleigh waves...

  14. Media literacy and remote community development in Eastern Indonesia Region

    Science.gov (United States)

    Aras, M.

    2018-03-01

    This study focused on media literacy phenomenon and educational development of remote communities in the eastern Indonesia region. Therefore, this study used the qualitative approach. The research was done by using direct observation and depth-interview. The research results showed that (1) the media literacy phenomenon of remote community in eastern Indonesia region was apprehensive. This was due to lack of access to information or media exposure through print media, electronic media, and social media. Therefore, the implication was the education awareness of the local community. The media literacy community has a strong relation with public awareness in improving education, and (2) the role of media in the development as facilitators or means of socialization to convey messages related to sustainable development programs in Indonesia. The current media phenomenon had become a necessity, without the exception of the remote communities. The development of an area was also characterized by the increasing education of its citizen and media became one of supporting factors that can motivate the citizen in gaining knowledge. It meant that media literacy community has strong relationships with people awareness in increasing their education. The more media literate, the more people have an awareness of self-development and their region development. Therefore, in the future, there will be no more remote areas because the media network has reached all areas.

  15. An empirical application of regional security complex theory on eastern partnership region

    Directory of Open Access Journals (Sweden)

    Ludmila STUPARU

    2015-12-01

    Full Text Available Eastern Partnership (EaP is a very dynamic region. If a year ago the EaP was seen as an authentic and vibrant „laboratory” of democracy building, overcoming the remains of the totalitarian state and putting the basis of a free and pluralist society, nowadays the Eastern Partnership is seen as an „out-dated” approach of the EU. However, Eastern Partnership is visible on European political arena and the big powers (USA, Russia and the EU pay attention more and more to the evolution of EaP countries. Moreover, it seems to be a confrontation between Russia and Western powers regarding the political and geopolitical orientation of EaP countries. Kremlin tries actively to stop the efforts of the EaP to close to the EU and on the other side, the EU as well as the USA encourage EaP countries to implement reforms in order to build their democracy. This paper aims to analyse the Eastern Partnership in terms of security complex, trying to argue that Eastern Partnership countries at this phase don’t form a Regional Security Complex and the EU and USA should rethink its approach towards this region.

  16. Physical activity and associated socio-demographic factors in adolescents from the eastern region of Poland

    Science.gov (United States)

    Wasilewska, Małgorzata; Bergier, Józef

    The introduction and maintenance of healthy habits in the field of physical activity at the early stage of life is particularly important for public health. With increasing of public awareness in physical activity, researchers are increasingly questioning its determinants in different age groups. In this paper we focus on variables such as age, sex and place of residence. To determine what selected socio-demographic factors influence the level of physical activity of school youth from the eastern region of Poland in different domains of daily life. A random sample of 916 Polish school youth from Secondary Schools from Eastern Region of Poland aged 16-18 was interviewed in spring 2016 by diagnostic survey method with the use of the official Polish long version of the International Physical Activity Questionnaire (IPAQ). Analysing the relationship between gender and the level of physical activity statistically significant differences were found in all domains in favour of boys. The level of total physical activity in girls was 5345.5 MET-min./week, whereas in boys – 6556.6 MET-min./week. In the area of total physical activity, the highest values were observed in pupils from small towns and villages, with lower values in the youth living in large and medium-sized cities. When the relationship of age with the level of physical activity in particular domains was examined, only the activity in the work/ school domain (p = 0.0129) spoke in favour of the youngest pupils (2578.7 MET-min./week) when compared to the oldest ones (2226.4 MET-min./week). The level of physical activity in young people from the Eastern region of Poland is decreasing with age, both in girls and boys. It is therefore important, especially for the group emerging adulthood, to offer a wide variety of updated, involving, age and gender-oriented school physical activity classes that could be easily practised outside the school environment to improve the level of physical activity in leisure domain

  17. Analysis of Regional GPS Networks in Eastern Ontario

    Science.gov (United States)

    Samadi Alinia, H.; Tiampo, K. F.

    2014-12-01

    Although stable, intraplate region of eastern Canada is considered low rate deformation area in the North American plate, the retreat of large ice sheets during deglaciation in the last 20 ka has resulted in horizontal and vertical deformation of the Earth's in eastern Ontario. Present-day glacial isostatic adjustment (GIA) uplift rates approach 10 mm/yr or more at Hudson Bay and decrease with distance southeastward. Current GIA models forecast that the hinge line between uplift to the northwest and subsidence to the southeast lies somewhere near the Saint Lawrence valley in eastern Canada [Tushingham and Peltier, 1991; Peltier, 2002]. Employing continuous Global Positioning System (cGPS) observations and high precision tools for processing and then analyzing each component of derived time series are important tools to monitor the associated regional crustal deformation with good accuracies. Here we describe the analysis of coordinate time series of cGPS stations scattered sparsely throughout southeastern Ontario and between Ottawa and the east coast of Hudson Bay. Here, the two most reliable local networks, each including 4 to 6 reference stations, were selected for analysis. Data for period of approximately five years, 2008-2012.9, was processed with Bernese 5.0 over several campaigns. Individual cGPS coordinate time series were generated for each station and basic parameters, such as mean, variance and repeatability, were estimated. The time series are corrected with respect to the rigid plate motion and seasonal variations and advanced time series analysis techniques, including spectral analysis and principal component analysis were implemented. Post-processing of the time series reproduces the general GIA spatial pattern. Results also show that the vertical velocities of all stations in the solution are consistent with the GIA model uplift rate and are consistent with other cGPS sites in eastern Canada and increases from north of lake of Ontario (approximately

  18. Characteristics of regional aerosols: Southern Arizona and eastern Pacific Ocean

    Science.gov (United States)

    Prabhakar, Gouri

    Atmospheric aerosols impact the quality of our life in many direct and indirect ways. Inhalation of aerosols can have harmful effects on human health. Aerosols also have climatic impacts by absorbing or scattering solar radiation, or more indirectly through their interactions with clouds. Despite a better understanding of several relevant aerosol properties and processes in the past years, they remain the largest uncertainty in the estimate of global radiative forcing. The uncertainties arise because although aerosols are ubiquitous in the Earth's atmosphere they are highly variable in space, time and their physicochemical properties. This makes in-situ measurements of aerosols vital in our effort towards reducing uncertainties in the estimate of global radiative forcing due to aerosols. This study is an effort to characterize atmospheric aerosols at a regional scale, in southern Arizona and eastern Pacific Ocean, based on ground and airborne observations of aerosols. Metals and metalloids in particles with aerodynamic diameter (Dp) smaller than 2.5 μm are found to be ubiquitous in southern Arizona. The major sources of the elements considered in the study are identified to be crustal dust, smelting/mining activities and fuel combustion. The spatial and temporal variability in the mass concentrations of these elements depend both on the source strength and meteorological conditions. Aircraft measurements of aerosol and cloud properties collected during various field campaigns over the eastern Pacific Ocean are used to study the sources of nitrate in stratocumulus cloud water and the relevant processes. The major sources of nitrate in cloud water in the region are emissions from ships and wildfires. Different pathways for nitrate to enter cloud water and the role of meteorology in these processes are examined. Observations of microphysical properties of ambient aerosols in ship plumes are examined. The study shows that there is an enhancement in the number

  19. CORAL: aligning conserved core regions across domain families.

    Science.gov (United States)

    Fong, Jessica H; Marchler-Bauer, Aron

    2009-08-01

    Homologous protein families share highly conserved sequence and structure regions that are frequent targets for comparative analysis of related proteins and families. Many protein families, such as the curated domain families in the Conserved Domain Database (CDD), exhibit similar structural cores. To improve accuracy in aligning such protein families, we propose a profile-profile method CORAL that aligns individual core regions as gap-free units. CORAL computes optimal local alignment of two profiles with heuristics to preserve continuity within core regions. We benchmarked its performance on curated domains in CDD, which have pre-defined core regions, against COMPASS, HHalign and PSI-BLAST, using structure superpositions and comprehensive curator-optimized alignments as standards of truth. CORAL improves alignment accuracy on core regions over general profile methods, returning a balanced score of 0.57 for over 80% of all domain families in CDD, compared with the highest balanced score of 0.45 from other methods. Further, CORAL provides E-values to aid in detecting homologous protein families and, by respecting block boundaries, produces alignments with improved 'readability' that facilitate manual refinement. CORAL will be included in future versions of the NCBI Cn3D/CDTree software, which can be downloaded at http://www.ncbi.nlm.nih.gov/Structure/cdtree/cdtree.shtml. Supplementary data are available at Bioinformatics online.

  20. Radioecological analysis of the north-eastern region of Poland

    International Nuclear Information System (INIS)

    Zalewski, M.; Mnich, Z.; Kapala, J.; Karpinska, M.

    1997-01-01

    This paper presents the results of measurements of natural radioactivity of K-40, Ra-226 and Th-232 in building material as well as radon concentrations and dose rates in houses and outdoors. The mean absorbed rate in air outdoors from natural gamma radiation was found to be 40.2 nGyh -1 . Doses inside houses made from particular materials were (nGyh -1 ): brick - 102, prefabricate - 89, wood - 88. The mean equivalent per one statistical inhabitant of ''Poland Green Lungs'' is 1.61 mSv/year. The doses absorbed by the population in the north-eastern region of Poland from natural sources of ionizing radiation are lower than the population-weighted world averages. (author)

  1. Seismic hazard assessment of the Hanford region, Eastern Washington State

    International Nuclear Information System (INIS)

    Youngs, R.R.; Coppersmith, K.J.; Power, M.S.; Swan, F.H. III

    1985-01-01

    A probabilistic seismic hazard assessment was made for a site within the Hanford region of eastern Washington state, which is characterized as an intraplate region having a relatively low rate of seismic activity. Probabilistic procedures, such as logic trees, were utilized to account for the uncertainties in identifying and characterizing the potential seismic sources in the region. Logic trees provide a convenient, flexible means of assessing the values and relative likelihoods of input parameters to the hazard model that may be dependent upon each other. Uncertainties accounted for in this way include the tectonic model, segmentation, capability, fault geometry, maximum earthquake magnitude, and earthquake recurrence rate. The computed hazard results are expressed as a distribution from which confidence levels are assessed. Analysis of the results show the contributions to the total hazard from various seismic sources and due to various earthquake magnitudes. In addition, the contributions of uncertainties in the various source parameters to the uncertainty in the computed hazard are assessed. For this study, the major contribution to uncertainty in the computed hazard are due to uncertainties in the applicable tectonic model and the earthquake recurrence rate. This analysis serves to illustrate some of the probabilistic tools that are available for conducting seismic hazard assessments and for analyzing the results of these studies. 5 references, 7 figures

  2. Determination of regional Euler pole parameters for Eastern Austria

    Science.gov (United States)

    Umnig, Elke; Weber, Robert; Schartner, Matthias; Brueckl, Ewald

    2017-04-01

    The horizontal motion of lithospheric plates can be described as rotations around a rotation axes through the Earth's center. The two possible points where this axes intersects the surface of the Earth are called Euler poles. The rotation is expressed by the Euler parameters in terms of angular velocities together with the latitude and longitude of the Euler pole. Euler parameters were calculated from GPS data for a study area in Eastern Austria. The observation network is located along the Mur-Mürz Valley and the Vienna Basin. This zone is part of the Vienna Transfer Fault, which is the major fault system between the Eastern Alps and the Carpathians. The project ALPAACT (seismological and geodetic monitoring of ALpine-PAnnonian ACtive Tectonics) investigated intra plate tectonic movements within the Austrian part in order to estimate the seismic hazard. Precise site coordinate time series established from processing 5 years of GPS observations are available for the regional network spanning the years from 2010.0 to 2015.0. Station velocities with respect to the global reference frame ITRF2008 have been computed for 23 sites. The common Euler vector was estimated on base of a subset of reliable site velocities, for stations directly located within the area of interest. In a further step a geokinematic interpretation shall be carried out. Therefore site motions with respect to the Eurasian Plate are requested. To obtain this motion field different variants are conceivable. In a simple approach the mean ITRF2008 velocity of IGS site GRAZ can be adopted as Eurasian rotational velocity. An improved alternative is to calculate site-specific velocity differences between the Euler rotation and the individual site velocities. In this poster presentation the Euler parameters, the residual motion field as well as first geokinematic interpretation results are presented.

  3. VOLCANIC TSUNAMI GENERATING SOURCE MECHANISMS IN THE EASTERN CARIBBEAN REGION

    Directory of Open Access Journals (Sweden)

    George Pararas-Carayannis

    2004-01-01

    Full Text Available Earthquakes, volcanic eruptions, volcanic island flank failures and underwater slides have generated numerous destructive tsunamis in the Caribbean region. Convergent, compressional and collisional tectonic activity caused primarily from the eastward movement of the Caribbean Plate in relation to the North American, Atlantic and South American Plates, is responsible for zones of subduction in the region, the formation of island arcs and the evolution of particular volcanic centers on the overlying plate. The inter-plate tectonic interaction and deformation along these marginal boundaries result in moderate seismic and volcanic events that can generate tsunamis by a number of different mechanisms. The active geo-dynamic processes have created the Lesser Antilles, an arc of small islands with volcanoes characterized by both effusive and explosive activity. Eruption mechanisms of these Caribbean volcanoes are complex and often anomalous. Collapses of lava domes often precede major eruptions, which may vary in intensity from Strombolian to Plinian. Locally catastrophic, short-period tsunami-like waves can be generated directly by lateral, direct or channelized volcanic blast episodes, or in combination with collateral air pressure perturbations, nuéss ardentes, pyroclastic flows, lahars, or cascading debris avalanches. Submarine volcanic caldera collapses can also generate locally destructive tsunami waves. Volcanoes in the Eastern Caribbean Region have unstable flanks. Destructive local tsunamis may be generated from aerial and submarine volcanic edifice mass edifice flank failures, which may be triggered by volcanic episodes, lava dome collapses, or simply by gravitational instabilities. The present report evaluates volcanic mechanisms, resulting flank failure processes and their potential for tsunami generation. More specifically, the report evaluates recent volcanic eruption mechanisms of the Soufriere Hills volcano on Montserrat, of Mt. Pel

  4. Famine foods in eastern regions of the Sudan

    Energy Technology Data Exchange (ETDEWEB)

    Ahmed, Badawi Ibrahim [Department of Biochemistry and Soil Sciences, Faculty of Agriculture, University of Khartoum, Khartoum (Sudan)

    1995-01-01

    A questionnaire was prepared for the collection of data concerning famine in eastern regions. Some of the data collected were concerning the availability and distribution of famine foods and their roles in times of famine. Mal-nutrition problems that a rise from the consequences of drought and famine were discussed in this study. In achieving this piece of current study on famine foods, a thorough computer literature search for each individual famine food was made for the last 15 years. During the field investigation 12 pieces of famine foods were found to grow in eastern regions. The chemical compositions for these famine foods were determined. Uncultivated cereals grains, difra and adar, were compared as regards their usage and chemical composition with some of local cultivated cereals dura and dukhn. The protein percentage of adar is 15.6%. This value is higher than that of dura variety safra. The crude fibre values of all studied plants were higher compared to cereal foods, ranging between 3.1-22.5%. Kawal in this study showed the highest value of protein but its unpleasant smell limits its consumption. The crude proteins of nabag, laloub pulp and doum exceeds the protein content of dates variety bentamoda as determined by Mustafa (1986). Arak, tondub, kawal, laloub leaves and nabag are high levels of sodium were found in doum, tondub and kawal. Fruit pulps of laloub, nabag, doum and arak are characterized by having a high proportion of sugars which are mostly non-reducing sugars. A high concentrations of arabinose were found in doum and difra. Other sugars detected were glucose, galactose and rhamnose. High levels of alcohol insoluble solids were found in molokhiat elkhalla, moliata, tamaleika and laloub leaves. Doum, laloub leaves, tamaleika were found to have high proportions of k {sup +} content, while high levels of Mg {sup +2} were found in kawal, difra, doum, tamaleika and laloub leaves. Total and reducing sugars were determined by titration and neutral

  5. Famine foods in eastern regions of the Sudan

    International Nuclear Information System (INIS)

    Ahmed, Badawi Ibrahim

    1995-01-01

    A questionnaire was prepared for the collection of data concerning famine in eastern regions. Some of the data collected were concerning the availability and distribution of famine foods and their roles in times of famine. Mal-nutrition problems that a rise from the consequences of drought and famine were discussed in this study. In achieving this piece of current study on famine foods, a thorough computer literature search for each individual famine food was made for the last 15 years. During the field investigation 12 pieces of famine foods were found to grow in eastern regions. The chemical compositions for these famine foods were determined. Uncultivated cereals grains, difra and adar, were compared as regards their usage and chemical composition with some of local cultivated cereals dura and dukhn. The protein percentage of adar is 15.6%. This value is higher than that of dura variety safra. The crude fibre values of all studied plants were higher compared to cereal foods, ranging between 3.1-22.5%. Kawal in this study showed the highest value of protein but its unpleasant smell limits its consumption. The crude proteins of nabag, laloub pulp and doum exceeds the protein content of dates variety bentamoda as determined by Mustafa (1986). Arak, tondub, kawal, laloub leaves and nabag are high levels of sodium were found in doum, tondub and kawal. Fruit pulps of laloub, nabag, doum and arak are characterized by having a high proportion of sugars which are mostly non-reducing sugars. A high concentrations of arabinose were found in doum and difra. Other sugars detected were glucose, galactose and rhamnose. High levels of alcohol insoluble solids were found in molokhiat elkhalla, moliata, tamaleika and laloub leaves. Doum, laloub leaves, tamaleika were found to have high proportions of k + content, while high levels of Mg +2 were found in kawal, difra, doum, tamaleika and laloub leaves. Total and reducing sugars were determined by titration and neutral sugars were

  6. Earthquake Swarm in Armutlu Peninsula, Eastern Marmara Region, Turkey

    Science.gov (United States)

    Yavuz, Evrim; Çaka, Deniz; Tunç, Berna; Serkan Irmak, T.; Woith, Heiko; Cesca, Simone; Lühr, Birger-Gottfried; Barış, Şerif

    2015-04-01

    The most active fault system of Turkey is North Anatolian Fault Zone and caused two large earthquakes in 1999. These two earthquakes affected the eastern Marmara region destructively. Unbroken part of the North Anatolian Fault Zone crosses north of Armutlu Peninsula on east-west direction. This branch has been also located quite close to Istanbul known as a megacity with its high population, economic and social aspects. A new cluster of microseismic activity occurred in the direct vicinity southeastern of the Yalova Termal area. Activity started on August 2, 2014 with a series of micro events, and then on August 3, 2014 a local magnitude is 4.1 event occurred, more than 1000 in the followed until August 31, 2014. Thus we call this tentatively a swarm-like activity. Therefore, investigation of the micro-earthquake activity of the Armutlu Peninsula has become important to understand the relationship between the occurrence of micro-earthquakes and the tectonic structure of the region. For these reasons, Armutlu Network (ARNET), installed end of 2005 and equipped with currently 27 active seismic stations operating by Kocaeli University Earth and Space Sciences Research Center (ESSRC) and Helmholtz-Zentrum Potsdam Deutsches GeoForschungsZentrum (GFZ), is a very dense network tool able to record even micro-earthquakes in this region. In the 30 days period of August 02 to 31, 2014 Kandilli Observatory and Earthquake Research Institute (KOERI) announced 120 local earthquakes ranging magnitudes between 0.7 and 4.1, but ARNET provided more than 1000 earthquakes for analyzes at the same time period. In this study, earthquakes of the swarm area and vicinity regions determined by ARNET were investigated. The focal mechanism of the August 03, 2014 22:22:42 (GMT) earthquake with local magnitude (Ml) 4.0 is obtained by the moment tensor solution. According to the solution, it discriminates a normal faulting with dextral component. The obtained focal mechanism solution is

  7. Epidemiology of hepetitis C infection, ERHA/HSE Eastern region.

    LENUS (Irish Health Repository)

    Meara, M O

    2007-02-01

    Hepatitis C became statutorily notifiable in Ireland on 1 January 2004. Prior to 2004, only hepatitis A and hepatitis B were notifiable as distinct types of hepatitis. A third category notifiable under the Infectious Diseases Regulations 1981 was "viral hepatitis unspecified". The majority of cases notified under this heading were thought to be due to infection with hepatitis C Virus (HCV). Between January 1 2004 and December 31 2005, the Department of Public Health HSE Eastern Region, received notification of 2,014 cases of HCV infection (2004, 941 cases, 2005 1,073 cases). This report outlines basic demographic details on cases notified and comments on missing data. Peak age band at notification for males and females is in the 25-29 year old age group where 538 (26.7%) were notified. Thirty cases notified (1.5%) were under 15 years of age. Drug misuse has been confirmed as a risk factor for 1247 (61.9%) of cases notified, and may be a risk factor in a large percentage of the reminder where risk factor data are unknown. Problems with completeness of notification have been identified. Enhanced surveillance of all hepatitis C infections is a prerequisite for future service planning.

  8. LOCAL DEVELOPMENT IN NORTHEST REGION THROUGH ACTIVITIES IN ITC DOMAIN

    Directory of Open Access Journals (Sweden)

    Daniela\tENACHESCU

    2015-06-01

    Full Text Available Economic areas with high technology are key drivers in sustainable regional development, including unemployment and consequently decreasing population migration in the region. Northeast Region is the largest development region of Romania in terms of number of inhabitants and the owned area. On 01/01/2014, according to balance employment, labor resources of the region were numbered 2,428,700, which represent 49.6% of employed population. The registered unemployment rate at 31 August 2014 was 6.5%, with 82 thousand unemployed registered. In terms of participation in the main economic activities, civilian employment in agriculture, forestry and fishing is predominant (40.1% while in service, civilian employment is 37.1%, while industry and construction is 22.8%. The paper aims to analyze the situation that the potential employment and development opportunities for the Northeast region through activities in the field of ITC domain. Unfortunately, this area was the worst in most indicators, the use of computers and the internet to the turnover of companies and investments in the IT & C and unfortunately in terms of employment population that is under 50%

  9. Biotechnological studies in the Far-Eastern Region of Russia.

    Science.gov (United States)

    Stonik, Valentin A; Mikhailov, Valery V; Bulgakov, Victor P; Zhuravlev, Yuri N

    2007-07-01

    Achievements and problems in both the studies on natural bioactive compounds from the Far-Eastern higher plants and marine invertebrates and development of the corresponding biotechnologies concerning new drugs and food supplements, as well as pharmaceutical leads are discussed. Special emphasis is made on recent results from the Far-eastern Institutions belonging to the Russian Academy of Sciences, and their application in both medicine and the food industry, as well as on peculiarities of biological and chemical diversity in the North-Western part of Asia and adjoining seas.

  10. Entrepreneurial orientation of eastern white pine primary producers and secondary manufacturers: A regional phenomenon?

    Science.gov (United States)

    Delton Alderman

    2011-01-01

    Eastern white pine (EWP) and red pine make up nearly 8.5 percent of the total sawtimber volume in the New England, Mid-Atlantic, and Lake States regions. The majority of white pine growing stock is found in the Mid-Atlantic and Lake State regions; however, the center of eastern white pine production and markets is in New England. EWP is produced in both hardwood...

  11. Coal resources of the eastern regions of Russia for power plants of the Asian super ring

    Science.gov (United States)

    Sokolov, Aleksander; Takaishvili, Liudmila

    2018-01-01

    The eastern regions of Russia have a substantial potential for expansion of steaming coal production. The majority of coal deposits in the eastern regions are located close enough to the objects of the Asian super ring. The large coal reserves make it possible to consider it as a reliable fuel source for power plants for a long-term horizon. The coal reserves suitable for using at power plants of the Asian super ring are estimated in the paper by subject of the federation of the eastern regions for operating and new coal producers. The coal deposits of the eastern regions that are promising for the construction of power plants of the Asian super ring are presented. The paper describes both the coal deposits of the eastern regions that are considered in the projects for power plant construction and included in the program documents and the coal deposits that are not included in the program documents. The coal reserves of these deposits and the possible volumes of its production are estimated. The key qualitative coal characteristics of the deposits: heating value, and ash, sulfur, moisture content are presented. The mining-geological and hydrological conditions for deposit development are briefly characterized. The coals of the eastern regions are showed to contain valuable accompanying elements. It is noted that the creation of industrial clusters on the basis of the coal deposits is the most effective from the standpoints of the economy and ecology. The favorable and restraining factors in development of the described coal deposits are estimated.

  12. Eastern Health Board Regional Orthodontic Service: an initial audit.

    LENUS (Irish Health Repository)

    Dowling, P A

    1997-01-01

    This initial audit of 600 recently assessed Eastern Health Board orthodontic patients suggests that a large number of them (47 per cent) requires referral for routine restorative and preventive dental care. Closer links are needed with general dental practitioners and community dental surgeons to resolve these needs. The trend for a high referral of females and Class 11 Division 1 malocclusion type correlated well with studies in other countries.

  13. The Middle Eastern Regional Irrigation Management Information Systems project-update

    Science.gov (United States)

    The Middle Eastern Regional Irrigation Management Information Systems Project (MERIMIS) was formulated at a meeting of experts from the region in Jordan in 2003. Funded by the U.S. Department of State, it is a cooperative regional project bringing together participants from Israel, Jordan, Palestini...

  14. Causality between regional stock markets: A frequency domain approach

    Directory of Open Access Journals (Sweden)

    Gradojević Nikola

    2013-01-01

    Full Text Available Using a data set from five regional stock exchanges (Serbia, Croatia, Slovenia, Hungary and Germany, this paper presents a frequency domain analysis of a causal relationship between the returns on the CROBEX, SBITOP, CETOP and DAX indices, and the return on the major Serbian stock exchange index, BELEX 15. We find evidence of a somewhat dominant effect of the CROBEX and CETOP stock indices on the BELEX 15 stock index across a range of frequencies. The results also indicate that the BELEX 15 index and the SBITOP index interact in a bi-directional causal fashion. Finally, the DAX index movements consistently drive the BELEX 15 index returns for cycle lengths between 3 and 11 days without any feedback effect.

  15. CLIMATE CHANGE AND ORIENTAL SPRUCE (PICEA ORIENTALIS ECOSYSTEMS IN EASTERN BLACKSEA REGION OF TURKEY

    Directory of Open Access Journals (Sweden)

    Aydın Tüfekçioğlu

    2008-04-01

    Full Text Available Climate change has been getting more attention from scientific community recently. Eastern Black Sea Region of Turkey will get significant influences from the climate change according to regional climate model (RegCM3. Oriental spruce (Picea orientalis L. is an important tree species of Turkey and it only grows in the Eastern Black Sea Region of Turkey. With the increase in global warming, spruce forests started to have serious bark beetle problems. More than 200 000 trees died in the region recently due to bark beetle attack. We used existing literature related to oriental spruce and future climate of the region and field observations done in the different times to assess current status of the spruce stands. Future climate of the region has been predicted using RegCM3 regional climate model. Climate change could significantly influence distribution, diversity, structure and stability of the oriental spruce ecosystems. According to RegCM3 regional climate model, the temperatures will increase 2-4 °C in the region in the next century. Future climate scenarios predict 200-300 mm increases in precipitation in the eastern part of the region while the western part won't have any increase in precipitation in the next century. Temperature increases in the western part of the region can cause more stress on spruce trees and would probably increase bark beetle attacks. Also, fire could become an important threat in the western part of the region. It is possible to observe 400-800 m upward shift in the spruce belt in the western part. Treeline of spruce stands would probably move upward both in western and eastern part of the North-eastern Blacksea Region.

  16. Microbiological properties of dystric cambisols in region of eastern Serbia depending on exploitation way

    OpenAIRE

    Rasulić, Nataša; Delić, Dušica; Stajković-Srbinović, Olivera; Jošić, Dragana; Dolovac, Nenad; Kuzmanović, Đorđe

    2013-01-01

    One of the most represented types of soil in the hilly-mountainous region of Eastern Serbia is the dystric cambisol. Aiming to establish biogenity of such type of soil in Eastern Serbia, representation of the total microflora, fungi, actinomycetes, ammonifiers, azotobacters and oligonitrofills has been examined as well as dehydrogenase activity of the stated type of soil. The samples were taken from soils used in three different ways: plough-fields, orchards and forests. The standard microbio...

  17. Evaluation of hospital-learning environment for pediatric residency in eastern region of Saudi Arabia

    Directory of Open Access Journals (Sweden)

    Waleed H. BuAli

    2015-04-01

    Full Text Available Purpose: No study had been conducted to assess the hospitals’ environment for learning purposes in multicenter sites in Saudi Arabia. It aims to evaluate the environment of hospitals for learning purposes of pediatric residents. Methods: We applied Postgraduate Hospital Educational Environment Measure (PHEEM to measure the learning environment at six teaching hospitals in the Eastern Region of Saudi Arabia from September to December 2013. Results: The number of respondents was 104 (86.7% out of 120 residents and 37 females and 67 male residents have responded. The residents’ response scored 100 out of 160 maximum score in rating of PHEEM that showed overall learning environment is favorable for training. There were some items in the social support domain suggesting improvements. There was no significant difference between male and female residents. There was a difference among the participant teaching hospitals (p<0.05. Conclusion: The result pointed an overall positive rating. Individual item scores suggested that their social life during residency could be uninspiring. They have the low satisfactory level and they feel racism, and sexual discrimination. Therefore, there is still a room for improvement.

  18. Integrated Scenarios of Regional Development in Two Semi-Arid States of North-Eastern Brazil

    NARCIS (Netherlands)

    Döll, Petra; Krol, Martinus S.

    2002-01-01

    Scenario analysis of the future is an important tool for supporting sustainability-oriented regional planning. To assist regional planning in two federal states in semi-arid North-eastern Brazil, Ceará and Piauí, we developed integrated qualitative¿quantitative scenarios that show potential

  19. Regional European Specialization and Concentration in Central and Eastern Europe

    Directory of Open Access Journals (Sweden)

    Valentin Neculita

    2015-09-01

    Full Text Available Enlargement has become a fundamental priority of the European Union after the 90’s. Up to now seven rounds have been held for enlarging the Community which initially was made up of six Member States (Belgium, Germany, France, Italy, Luxembourg, Netherlands. Among all EU enlargements, the eastward enlargement from 2004 was the biggest challenge, both due to the number of new Member States which joined - the number of EU inhabitants increasing to approximately from 380 to 485 million, but also due to the difference of Gross Domestic Product between the old and new EU members. This paper aims to provide insights in European integration and absorption of European funds into the newest that joined the European Union. The paper proposes an analysis of integration and specialization in Eastern Europe by means of data and statistics provided by European and national statistics institutions.

  20. Sarcoidosis in the eastern region of Saudi Arabia

    Directory of Open Access Journals (Sweden)

    Al-Khouzaie Thamer

    2011-01-01

    Full Text Available Aim: To review a general hospital′s experience with sarcoidosis and the clinical pattern of the disease among Saudis. Methods: A retrospective file review was carried out on all patients with a proven diagnosis of sarcoidosis in a general hospital in Eastern Saudi Arabia over a period of 11 years (1998-2008. Results: Sixty-nine patients, of whom 33 cases were included in the analyses, were diagnosed to have sarcoidosis during the study period. There were 18 females and 15 males. The mean age was 44.5 years (SD 17. The most common presentations were cough (48%, dyspnea (21%, joint pain (18%, splenomegaly (12%, hepatomegaly (9%, and lymphadenopathy (5%. The biochemical analysis showed elevated calcium levels in 6% and elevated angiotensin converting enzyme (ACE in 14 (46.7%. The tuberculin skin test was negative in all tested patients (n = 29 except one patient. The patients were classified using the modified Scadding classification system. None of the patients was in stage 0, 39.4% were in stage 1, 45% were in stage 2 and 15% were in stage 3.. The diagnosis in all patients was proven histologically. The outcome was favorable in most patients (85%, and in 6% of the patients, the course was chronic and progressive, although 66% received active treatment. Conclusion: Sarcoidosis does occur in native Saudis. The clinical presentation of these patients was similar to the western pattern of disease with some differences such as relative lack of cardiac, eye, parotid, and central nervous system involvement. The rarity of cardiac and central nervous system involvement was comparable with other Middle Eastern studies. Sarcoidosis, though rare in our community, should still be considered in the differential diagnosis of patients with the typical presentation after excluding tuberculosis.

  1. EASTERN EUROPE, A REGION OF INSECURITY IN THE EUROPEAN UNION'S VICINITY

    Directory of Open Access Journals (Sweden)

    Bogdan – Lucian Cumpanasu

    2014-08-01

    Full Text Available During Cold War, the region of Eastern Europe was formed by European states that were behind the Iron Curtain.Once the communism has fallen and former Warsaw's Pact members have joined EU in 2004 and 2007 along with the Baltic republics, a New Eastern Europe comprising Ukraine, Republic of Moldova and the Caucasian Republics emerged at the border of EU. The north, west and south maritime frontiers of European Union are opposite with Eastern territorial one that are more difficult to control and defend against asymmetrical threats as: organized crime, drugs traffic, arms proliferation and illegal immigration. this paper aims to demonstrate that EU's policies initiated in the framework of Eastern Partnership (EaP that wanted to bring peace in the Eastern neighborhood did not succeed to fulfill the desired goals. One explanation is that EU did not take in consideration the Russian dream of redesigning its sphere of influence in Eastern Europe. Another one is that the cultural, political and social differences between EU and its EaP partners led to the failure of the project. Thus, European Union's actions toward Eastern vicinity led to a clash between two civilizations: East and West as well as to a geopolitical competition between Russian Federation and EU over their shared neighborhood.

  2. Geothermal systems of the Mono Basin-Long Valley region, eastern California and western Nevada

    Energy Technology Data Exchange (ETDEWEB)

    Higgins, C.T.; Flynn, T.; Chapman, R.H.; Trexler, D.T.; Chase, G.R.; Bacon, C.F.; Ghusn, G. Jr.

    1985-01-01

    The region that includes Mono Basin, Long Valley, the Bridgeport-Bodie Hills area, and Aurora, in eastern California and western Nevada was studied to determine the possible causes and interactions of the geothermal anomalies in the Mono Basin-Long Valley region as a whole. A special goal of the study was to locate possible shallow bodies of magma and to determine their influence on the hydrothermal systems in the region. (ACR)

  3. Eastern Canadian crude oil supply and its implications for regional energy security

    International Nuclear Information System (INIS)

    Hughes, Larry

    2010-01-01

    Canada has been blessed with immense energy resources; however, their distribution is not uniform. One such example is crude oil, which is found primarily in western Canada. Eastern Canada, consisting of the six eastern-most provinces (Newfoundland and Labrador, New Brunswick, Nova Scotia, Ontario, Prince Edward Island, and Quebec), produce limited quantities of crude oil, most of which is exported to the United States. Ideally, western Canadian crude oil would meet the demands of eastern Canada; however, the North American Free Trade Agreement (NAFTA) and the absence of oil pipelines means that eastern Canada increasingly relies on supplies of crude oil from a small number of oil exporting countries, many with declining production. This paper examines crude oil production, supply, and its refining in eastern Canada. It shows that crude production in the region has reached its peak and that increasing global competition for crude oil will affect energy security in eastern Canada, either through price increases or supply shortages, or both. (author)

  4. Regionalization of Crustal and Upper Mantle Q Structure in Eastern Eurasia Using Multiple Regional Waves

    National Research Council Canada - National Science Library

    Gaherty, James; Lerner-Lam, Arthur

    2007-01-01

    .... The Q Omicron model contains values that vary between 100 and 900. Q Omicron are the lowest in the Tibetan plateau, increase to moderate levels towards the east and north, and reach maxima in the Siberian and eastern Europe Cratons...

  5. Prevalence of child injuries in Mbale region, Eastern Uganda ...

    African Journals Online (AJOL)

    Background: The rate of unintentional child injuries in sub-Saharan Africa is at 53.1 per 100,000, The highest for low income regions, data on these injuries and associated factors among children in Uganda is very scanty. Most child injuries are related to the way of life in rural communities typically burns from charcoal ...

  6. Source region and sector contributions of atmospheric soot particle in a coalfield region of Dhanbad, eastern part of India

    Science.gov (United States)

    Singh, S.; Tiwari, S.; Dumka, U. C.; Kumar, R.; Singh, P. K.

    2017-11-01

    Black carbon (BC) aerosols affect the Earth's climate directly by interacting with the solar radiation and indirectly by modifying the lifetime and optical properties of clouds. However, our understanding of BC aerosols and their impacts on the climate are limited by lack of in situ measurements of BC, especially in the developing world. This study reports measurements of BC from Dhanbad, a coalfields area of eastern India, we analyze BC data at 370 and 880 nm during 2013 to gain insight into the emission sources affecting the study area. Our analysis indicates significantly higher absorption at the lower wavelength (ultraviolet). We estimate that 33% of BC at Dhanbad comes from biomass/biofuel combustion and the remaining 67% from the fossil fuel combustion. Higher concentrations of BC370 nm (> 12 μg m- 3) were observed when the air masses affecting Dhanbad originated far away in countries like Iran, Afghanistan, Pakistan, Oman, United Arab Emirates and passed over the Indo-Gangetic Plains (IGP) prior to arriving at the observation site. The source regions affecting BC880 nm were localized over the IGP but BC880 nm concentrations are 33% lower ( 8 μg m- 3) than BC370 nm. The cluster analysis showed that the largest fraction (35 and 29%) of the air masses arriving at Dhanbad passed through the boundary layer of the central IGP and north-west IGP region during the post-monsoon season. Average values of BC370 nm (16.0 and 20.0 μg m- 3) and BC880 nm (9.5 and 10.0 μg m- 3) in the IGP influenced air masses were significantly higher than those arriving from other source regions. The Weather Research and Forecasting model coupled with Chemistry (WRF-Chem) model were applied to understand the relative importance of different sources affecting Dhanbad. The variability of observed BC mass concentrations was captured fairly well by WRF-Chem with minor deviations from the measured values. Model results indicate that anthropogenic emissions account for more than 75% of the

  7. Participatory Governance in Secondary Schools: The Students' Viewpoint in Eastern Region of Kenya

    Science.gov (United States)

    Mulwa, David M.; Kimosop, Maurice K.; Kasivu, Gedion M.

    2015-01-01

    The purpose of the study was to determine the students' view on participatory school governance in secondary schools of the Eastern region, Kenya. Participatory school governance implies the involvement of stakeholders in the decision making process in schools. The objectives of the study were to identify the key decision makers in selected…

  8. Transactions of the 1982 Eastern Regional American Nuclear Society student conference

    International Nuclear Information System (INIS)

    1982-01-01

    The 1982 Eastern Region ANS Student Conference of the ANS Student Branch and the School of Nuclear Engineering and Health Physics was held at Georgia Tech., April 16-17, 1982. Almost all the papers have been entered individually into EDB and ERA

  9. Effect of solar flare on the equatorial electrojet in eastern Brazil region

    Indian Academy of Sciences (India)

    The effect of solar flare, sudden commencement of magnetic storm and of the disturbances ring current on the equatorial electrojet in the Eastern Brazil region, where the ground magnetic declination is as large as 20∘W is studied based on geomagnetic data with one minute resolution from Bacabal during ...

  10. Restoring oak ecosystems on national forest system lands in the eastern region: an adaptive management approach

    Science.gov (United States)

    Gregory Nowacki; Michael Ablutz; Dan Yaussy; Thomas Schuler; Dan Dey

    2009-01-01

    The U.S. Forest Service has recently completed an ecosystem restoration framework and enacted accompanying policy to help guide its nationwide efforts. The Eastern Region is in the midst of translating the general guidance set forth in these documents to actual on-the-ground restoration. We envision a set of coordinated field demonstrations that will initially focus on...

  11. Comparison of COSMIC measurements with the IRI-2007 model over the eastern Mediterranean region

    Directory of Open Access Journals (Sweden)

    P. Vryonides

    2013-05-01

    Full Text Available This paper presents a comparison of the International Reference Ionosphere (IRI-2007 model over the eastern Mediterranean region with peak ionospheric characteristics (foF2–hmF2 and electron density profiles measured by FORMOSAT-3/COSMIC satellites in terms of GPS radio occultation technique and the Cyprus digisonde. In the absence of systematic ionosonde measurements over this area, COSMIC measurements provide an opportunity to perform such a study by considering observations for year 2010 to investigate the behaviour of the IRI-2007 model over the eastern Mediterranean area.

  12. A research on consumer satisfaction and shopping patterns of households in the North Eastern Savo region

    OpenAIRE

    Taavitsainen, Ossi

    2015-01-01

    This Bachelor’s thesis deals with shopping patterns of consumers and their satisfaction with local supply of goods in the North Eastern Savo region in Finland. The thesis was conducted as a follow-up research to the original research made by a student of the University of Eastern Finland in 2009-2010. The theoretical part of the thesis consists of two main topics: purchase behavior of consumers and development of online shopping. The empirical part is based on a survey, conducted among consum...

  13. Program of Regional Collaboration between Eastern Part of Russia and Northeast China: Present and Future

    OpenAIRE

    Dmitriy Aleksandrovich Izotov

    2014-01-01

    The author uses Russian and Chinese sources of information to analyze the current status and evaluate realization prospects of investment projects within the Cooperation Program between eastern regions of Russia and northeast China. State budget financed construction of transport and border infrastructure is being implemented as planned both in Russia and China. Sectoral distribution of key Program projects is found to be unbalanced: Russian regions specialize in mining and primary processing...

  14. Behavioral Determinants of Russian Nuclear State-Owned Enterprises in Central and Eastern European Region

    OpenAIRE

    Vlcek, Tomas; Jirusek, Martin

    2015-01-01

    Rosatom State Nuclear Corporation play a substantial role in the energy sector of the Central and Eastern European region and the behavioral characteristics of the company forms the basis of this article. Rosatom is positioned as the dominant provider of nuclear technology and fuel supplies to the region, in large part stemming from the Soviet legacy in CEE countries. Compounding this challenge, nuclear energy is one of the major sources of power generation in CEE. Given the long-time, near m...

  15. Pattern of Occurrence of Leukemia at a Teaching Hospital in Eastern Region of Nepal - A Six Year Study

    Directory of Open Access Journals (Sweden)

    Ritu Kulshrestha

    2009-01-01

    The data published in this study reflects the leukemia pattern in the eastern region of Nepal. The pattern and distribution of AML, CML, ALL was similar to that in the developed western countries while the lesser frequency of CLL was similar to that in Southeast Asian region Key Words:leukemia, pattern, eastern Nepal, seasonality.

  16. Domestic violence against women in Kersa, Oromia region, eastern Ethiopia

    DEFF Research Database (Denmark)

    Shanko, W.; Wolday, M.; Assefa, N.

    2013-01-01

    Intimate partner violence is common in rural areas of Ethiopia. The aim of this study was to assess the knowledge and prevalence of domestic violence among women in Kersa district of Oromia region and identify the types, perpetuators and triggers for violence. A community-based cross...... husbands. Ever experience of domestic violence among women was significantly related to Amhara ethnicity and age group 30-49 years. Only 33 (19.9%) women who ever experienced violence had reported it to the legal authorities. Women's reasons for failing to report to the legal system were not wanting......-sectional interview-based survey was conducted in 2008 on 858 women of reproductive age. Only 39.7% of women reported that they recognized that violence against women was a problem in their area. Ever experience of violence by an intimate partner was reported by 166 women (19.6%) and 70.3% of the perpetuators were...

  17. [Tobacco smoking prevalence among students from Euro region Eastern Carpathians].

    Science.gov (United States)

    Zadarko, Emilian; Penar-Zadarko, Beata; Barabasz, Zbigniew

    2010-01-01

    Publisher in February 2008 WHO M-POWER report indicates that every year on the world tobacco epidemics kills 5.4 million of people and the analysis of tobacco smoking prevalence change shows great differences between European countries. It is estimated that in Poland 29% of adult people smokes, and 24% in Slovakia. However tobacco smoking among academic youth is still a big problem. The aim of the study was an attempt to estimate tobacco smoking prevalence among students from Poland and Slovakia. The study was conducted with the framework of science project: "Physical activity for the whole life". The aim of the project are multidirectional activities addressed to Polish-Slovakian students to create a system of taking care about health based on health education among students, selected modifying cardiovascular risk factors monitoring, as well as creating Internet portal to serve those goals. Project was co-fund by European Union from European Regional Development Fund - ERDF, as well as from the government budget by Euro Region Carpathians with the framework of Cross-border Co-operation Programme Republic of Poland - Slovakia Republic 2007-2013. Analysis considered 4584 group of students from University of Rzeszow and University of Presov, Technical University in Rzeszow and State Higher Vocational School in Krosno. The study was conducted from November 2009 to June 2010. The participation in the study was voluntary. The study was conducted using a diagnostics survey method with questionnaire. Chi-square test was used for statistical analysis. Based on results it was claimed that the majority of the studied group of students have never smoked and do not smoke cigarettes. Place of residence was a factor influencing the fact of tobacco smoking. Slovakian students were characterized by more frequent tobacco smoking. Far more often smoke man, both in Polish and Slovakian group. Among Polish students there was a relation between subjective health state assessment and

  18. GROWING REGIONAL SCIENTIFIC MIGRATION AND MOBILITY: THE EUROPEAN UNION AND THE EASTERN PARTNERSHIP

    Directory of Open Access Journals (Sweden)

    Ganna KHARLAMOVA

    2016-11-01

    Full Text Available The article contributes to the growing strand of the literature on the scientific mobility and migration in the European Union (EU and the Eastern Partnership. The paper provides the quantitative assessment of the costs and benefits of ‘smart’ labour migration in the Eastern Partnership (EaP countries (particularly, Ukraine, explores the potential of future new rules for the mobility within the EU-EaP, and proposes some policy recommendations to enhance the benefits stemming from such flows. One of the rigorous idea – to provide an explanation whether the scientific migration and mobility, and remittances impact on economic development in the donor and recipient states, and, in particular, how important it is as a resource for the EaP enhancing. The convergence effect of scientific migration in the EU and the Eastern Partnership region is considered by means of calculative assessment.

  19. Nanosecond Characterization of Regional Domain Imprint from Fast Domain Switching Currents in Pb(Zr,Ti)O_3 Thin Films

    International Nuclear Information System (INIS)

    Jun Jiang; An-Quan Jiang

    2016-01-01

    The traditional imprint characterization of ferroelectric thin films estimates imprint time dependence of the mean coercive voltage of all domains from a polarization-voltage hysteresis loop, which shows a semilogarithmic time dependence above an initial imprint time of τ_0 > 1 μs at room temperature. Below τ_0, the imprint effect is believed to be weak. In consideration of region-by-region domain reversal under a rising pulsed voltage with ordered coercive voltages increasing from zero up to the maximum applied voltage during capacitor charging time, we can estimate the imprinted coercive voltage of each domain from domain switching current transient separately with imprint time as short as 20 ns. In disagreement with the previous observations, all imprinted coercive voltages for the domains in Pt/Pb(Zr_0_._4Ti_0_._6)O_3/Pt thin-film capacitors show step-like increases at two characteristic times of 300 ns and 0.27s. The imprint effect is surprisingly strong enough even at shortened time down to 20 ns without any evidence of weakening. (paper)

  20. Specificity of Atmosphere Correction of Satellite Ocean Color Data in Far-Eastern Region

    Science.gov (United States)

    Trusenkova, O.; Kachur, V.; Aleksanin, A. I.

    2016-02-01

    It was carried out an error analysis of satellite reflectance coefficients (Rrs) of MODIS/AQUA colour data for two atmospheric correction algorithms (NIR, MUMM) in the Far-Eastern region. Some sets of unique data of in situ and satellite measurements have been analysed. A set has some measurements with ASD spectroradiometer for each satellite pass. The measurement allocations were selected so the Chlorophyll-a concentration has high variability. Analysis of arbitrary set demonstrated that the main error component is systematic error, and it has simple relations on Rrs values. The reasons of such error behavior are considered. The most probable explanation of the large errors of oceanic color parameters in the Far-Eastern region is the ability of high concentrations of continental aerosol. A comparison of satellite and in situ measurements at AERONET stations of USA and South Korea regions has been made. It was shown that for NIR-correction of the atmosphere influence the error values in these two regions have differences up to 10 times for almost the same water turbidity and relatively good accuracy of computation of aerosol optical thickness. The study was supported by grant Russian Scientific Foundation No. 14-50-00034, by grant of Russian Foundation of Basic Research No.15-35-21032-mol-a-ved, and by Program of Basic Research "Far East" of Far Eastern Branch of Russian Academy of Sciences.

  1. A Comparison of Moment Rates for the Eastern Mediterranean Region from Competitive Kinematic Models

    Science.gov (United States)

    Klein, E. C.; Ozeren, M. S.; Shen-Tu, B.; Galgana, G. A.

    2017-12-01

    Relatively continuous, complex, and long-lived episodes of tectonic deformation gradually shaped the lithosphere of the eastern Mediterranean region into its present state. This large geodynamically interconnected and seismically active region absorbs, accumulates and transmits strains arising from stresses associated with: (1) steady northward convergence of the Arabian and African plates; (2) differences in lithospheric gravitational potential energy; and (3) basal tractions exerted by subduction along the Hellenic and Cyprus Arcs. Over the last twenty years, numerous kinematic models have been built using a variety of assumptions to take advantage of the extensive and dense GPS observations made across the entire region resulting in a far better characterization of the neotectonic deformation field than ever previously achieved. In this study, three separate horizontal strain rate field solutions obtained from three, region-wide, GPS only based kinematic models (i.e., a regional block model, a regional continuum model, and global continuum model) are utilized to estimate the distribution and uncertainty of geodetic moment rates within the eastern Mediterranean region. The geodetic moment rates from each model are also compared with seismic moment release rates gleaned from historic earthquake data. Moreover, kinematic styles of deformation derived from each of the modeled horizontal strain rate fields are examined for their degree of correlation with earthquake rupture styles defined by proximal centroid moment tensor solutions. This study suggests that significant differences in geodetically obtained moment rates from competitive kinematic models may introduce unforeseen bias into regularly updated, geodetically constrained, regional seismic hazard assessments.

  2. The place and role of Ukraine in modern geopolitical processes in the Eastern European region

    Directory of Open Access Journals (Sweden)

    Bostan Sergii Ivanovich

    2014-07-01

    Full Text Available The Eastern European region has always attracted attention of the international community and was a stumbling block between the western and eastern leaders. Ukraine is the largest country in the region with a great development potential, it plays a key role in division of powers and spheres of influence across the continent. Preferences in Ukraine's foreign policy have been influencing both on the internal politics of the state and the balance between the major "players" on the political map of the world: EU, USA and Russia. These preferences also largely depend on the policy of these countries regarding Ukraine itself. Ukraine's participation in the contemporary geopolitical processes, its positioning and foreign policy priorities will play an important role in redistribution of influence in Europe and in the world, and particularly affect the development of relations between the world powers.

  3. USING RENEWABLE ENERGY SOURCES IN DEVELOPMENT OF THE FAR EASTERN REGION OF THE RUSSIAN FEDERATION

    OpenAIRE

    Monahov Boris Evgen'evich; Shilova Ljubov' Andreevna

    2012-01-01

    Today, Russian Far East represents a transit hub connecting Europe and Russia with Southeast Asia, Japan and America. The optimal pattern of its development involves its economic growth in combination with the implementation of major investment projects to be funded by the state and private investors. Despite substantial local problems, development of eastern regions is the top-priority task for Russian and international businesses. The paper proposes several alternative solutions to the p...

  4. A review of HIV testing and counseling policies and practices in the Eastern Mediterranean Region.

    Science.gov (United States)

    Hermez, Joumana; Petrak, Jenny; Karkouri, Mehdi; Riedner, Gabriele

    2010-07-01

    To review HIV testing and counseling policies and practices in the World Health Organization's (WHO) Eastern Mediterranean Region. We reviewed gray and published literature on HIV testing policies and practices in the 22 countries of the Eastern Mediterranean Region, including surveillance, monitoring and evaluation reports. Missing or unclear information was clarified by telephone interviews of key informants. Field observations were conducted in four countries. Of reported diagnostic HIV tests conducted in the Eastern Mediterranean Region from 1995 to 2008, 59.3% were carried out on migrant workers. Only 4.0% were carried out on key populations at higher risk for HIV and 8.1% were conducted in sexually transmitted infection, tuberculosis and antenatal care services. The largest proportions of HIV-positive cases identified were among key populations at higher risk (23.4%) and in sexually transmitted infection, tuberculosis and antenatal care services (17.5%). Mandatory testing was the most common approach to identifying HIV-positive cases, yet most policy documents reviewed identified voluntary counseling and testing as a key intervention for prevention, care and treatment. Provider initiated testing and counseling was rarely considered. HIV testing strategies are cumbersome, as they require central laboratory-based Enzyme Linked Immuno-Sorbant Assay (ELISA) and/or Western Blot confirmation in most countries presenting barriers to receiving results. Although policies in the Eastern Mediterranean Region include a mix of mandatory and voluntary HIV testing, mandatory testing predominates, especially for migrant and foreign workers and key populations at higher risk of HIV. There is a paucity of programs providing voluntary testing. Strategies to enhance access to true voluntary HIV testing and counseling services are urgently needed, particularly targeting key populations at higher risk.

  5. Periodontal disease awareness among pregnant women in the central and eastern regions of Saudi Arabia.

    Science.gov (United States)

    Asa'ad, Farah A; Rahman, Ghousia; Al Mahmoud, Noura; Al Shamasi, Ebtehaj; Al Khuwaileidi, Abrar

    2015-02-01

    The purpose of this study was to assess the knowledge and awareness regarding periodontal disease and its effects on pregnancy among pregnant women in the central and eastern regions of Saudi Arabia. In this cross-sectional survey, self-administered, structured questionnaires were distributed to 300 pregnant women who were chosen randomly from attendees of maternity health care centers in the central and eastern regions of Saudi Arabia. The questions were developed from literature reviews of articles. The questionnaire addressed personal and sociodemographic variables, periodontal health awareness, and knowledge of pregnant women. The questionnaire was translated into Arabic and was pretested during the pilot study on a random sample of 50 pregnant women. Data were analyzed by χ(2) -tests, with the level of significance set at P disease could be prevented through toothbrushing and flossing. Approximately 97% of the respondents knew the negative effect of smoking, while only 12% knew there was a possible relationship between periodontal disease and adverse pregnancy outcomes. The results of this cross-sectional study found that there is limited knowledge and awareness about periodontal disease and its possible effects on pregnancy among pregnant women attending maternal health care centers in the central and eastern regions of Saudi Arabia. © 2013 Wiley Publishing Asia Pty Ltd.

  6. Regional approach to building operational level capacity for disaster planning: the case of the Eastern Africa region.

    Science.gov (United States)

    Bazeyo, W; Mayega, R W; Orach, G C; Kiguli, J; Mamuya, S; Tabu, J S; Sena, L; Rugigana, E; Mapatano, M; Lewy, D; Mock, N; Burnham, G; Keim, M; Killewo, J

    2013-06-01

    The Eastern Africa region is regularly affected by a variety of disasters ranging from drought, to human conflict and population displacement. The magnitude of emergencies and response capacities is similar across the region. In order to strengthen public health disaster management capacities at the operational level in six countries of the Eastern Africa region, the USAID-funded leadership project worked through the HEALTH Alliance, a network of seven schools of public health from six countries in the region to train district-level teams. To develop a sustainable regional approach to building operational level capacity for disaster planning. This project was implemented through a higher education leadership initiative. Project activities were spear-headed by a network of Deans and Directors of public health schools within local universities in the Eastern Africa region. The leadership team envisioned a district-oriented systems change strategy. Pre-service and in-service curricula were developed regionally and district teams were formed to attend short training courses. Project activities began with a situational analysis of the disaster management capacity at national and operational levels. The next steps were chronologically the formation of country training teams and training of trainers, the development of a regional disaster management training curriculum and training materials, the cascading of training activities in the region, and the incorporation of emerging issues into the training curriculum. An evaluation model included the analysis of preparedness impact of the training program. The output from the district teams was the creation of individual district-level disaster plans and their implementation. This 4-year project focused on building operational level public health emergency response capacity, which had not previously been part of any national program. Use of the all-hazard approach rather than a scenario-based contingency planning led to the

  7. Fine-tuning of protein domain boundary by minimizing potential coiled coil regions

    International Nuclear Information System (INIS)

    Iwaya, Naoko; Goda, Natsuko; Unzai, Satoru; Fujiwara, Kenichiro; Tanaka, Toshiki; Tomii, Kentaro; Tochio, Hidehito; Shirakawa, Masahiro; Hiroaki, Hidekazu

    2007-01-01

    Structural determination of individual protein domains isolated from multidomain proteins is a common approach in the post-genomic era. Novel and thus uncharacterized domains liberated from intact proteins often self-associate due to incorrectly defined domain boundaries. Self-association results in missing signals, poor signal dispersion and a low signal-to-noise ratio in 1 H- 15 N HSQC spectra. We have found that a putative, non-canonical coiled coil region close to a domain boundary can cause transient hydrophobic self-association and monomer-dimer equilibrium in solution. Here we propose a rational method to predict putative coiled coil regions adjacent to the globular core domain using the program COILS. Except for the amino acid sequence, no preexisting knowledge concerning the domain is required. A small number of mutant proteins with a minimized coiled coil region have been rationally designed and tested. The engineered domains exhibit decreased self-association as assessed by 1 H- 15 N HSQC spectra with improved peak dispersion and sharper cross peaks. Two successful examples of isolating novel N-terminal domains from AAA-ATPases are demonstrated. Our method is useful for the experimental determination of domain boundaries suited for structural genomics studies

  8. Fine-tuning of protein domain boundary by minimizing potential coiled coil regions.

    Science.gov (United States)

    Iwaya, Naoko; Goda, Natsuko; Unzai, Satoru; Fujiwara, Kenichiro; Tanaka, Toshiki; Tomii, Kentaro; Tochio, Hidehito; Shirakawa, Masahiro; Hiroaki, Hidekazu

    2007-01-01

    Structural determination of individual protein domains isolated from multidomain proteins is a common approach in the post-genomic era. Novel and thus uncharacterized domains liberated from intact proteins often self-associate due to incorrectly defined domain boundaries. Self-association results in missing signals, poor signal dispersion and a low signal-to-noise ratio in (1)H-(15)N HSQC spectra. We have found that a putative, non-canonical coiled coil region close to a domain boundary can cause transient hydrophobic self-association and monomer-dimer equilibrium in solution. Here we propose a rational method to predict putative coiled coil regions adjacent to the globular core domain using the program COILS. Except for the amino acid sequence, no preexisting knowledge concerning the domain is required. A small number of mutant proteins with a minimized coiled coil region have been rationally designed and tested. The engineered domains exhibit decreased self-association as assessed by (1)H-(15)N HSQC spectra with improved peak dispersion and sharper cross peaks. Two successful examples of isolating novel N-terminal domains from AAA-ATPases are demonstrated. Our method is useful for the experimental determination of domain boundaries suited for structural genomics studies.

  9. Communicable diseases in the Eastern Mediterranean Region: prevention and control 2010-2011.

    Science.gov (United States)

    Haq, Z; Mahjour, J; Khan, W

    2013-10-01

    One-third of all morbidities and mortalities in the Eastern Mediterranean Region are attributed to communicable diseases. A continued situation of war and conflict, and growing political unrest in the Region, coupled with factors such as travel and migration, and insufficient infrastructure and inadequate technical and managerial capacity ofthe programmes are the major challenges. Despite these challenges, the Region continued making progress towards the elimination of specific diseases such as lymphatic filariasis, measles, malaria, schistosomiasis and dracunculiasis during 2010-11. Coverage for vaccine-preventable diseases was enhanced. Preparedness and response to emerging (e.g. dengue fever in Pakistan and Yemen) and re-emerging (e.g. cholera in Sudan) infections was improved. The Region has continued its efforts for controlling tuberculosis and curbing HIV/AIDS. Looking ahead, the Region aims to improve surveillance and response capacities, legislation issues, coordination, bio-risk and bio-security and quality management in the coming years.

  10. Structuring and evolution of Neogene transcurrent basins in the Tellian foreland domain, north-eastern Tunisia

    Science.gov (United States)

    Melki, Fetheddine; Zouaghi, Taher; Harrab, Salah; Sainz, Antonio Casas; Bédir, Mourad; Zargouni, Fouad

    2011-07-01

    The Neogene sedimentary basins (Serravallian to Quaternary) of the Tellian tectonic foreland in north-eastern Tunisia formed within the overall NE-SW sinistral strike-slip tectonic framework of the Ras El Korane-Thibar and El Alia-Teboursouk fault systems. From stratigraphic logs, structural cross sections and interpretation of 2D seismic lines and boreholes, the pre-Neogene basement can be interpreted to be structured according to Eocene (NW-SE) compressional and Oligocene extensional phases. This basement comprises structural highs (anticlines and horsts) and subsiding areas (synclines, half-grabens and grabens) formed during the Neogene. The subsiding areas are delineated by faults striking N030E, N-S and N140E, defining (i) narrow, strongly subsiding synclines, (ii) lozenge-shaped basins and (iii) trapezoidal basins. The architecture of their fill results from the sedimentary balance between tectonics and eustatism. Halokinesis and clay diapirism (driven by Triassic and Neogene evaporites and clays) also played an important role in basin evolution, contributing to the formation of domes and diapirs along active faults.

  11. Siliguri: A Geopolitical Manoeuvre Corridor in the Eastern Himalayan Region for China and India

    Directory of Open Access Journals (Sweden)

    Hasan Yaser Malik

    2015-12-01

    Full Text Available Siliguri Corridor being part of Indian West Bengal is a diplomatic manoeuvre place located between Nepal, Bhutan, Bangladesh, India’s Seven Sister States and Chumbi Hills in the Eastern Himalayan Region. Being located at the crossroads and centrally situated between all the neighbouring countries the landlocked Siliguri has an especially economic and political value for the regional countries. The corridor being in close proximity to China and India’s Seven Sister States has added to the diplomatic mosaic of the Eastern Himalayan Region. The region consists of beautiful landscape, mountains and rivers which not only add to topographical diversity but also demographic mixture. Despite its geopolitical significance the area could not advance for not only being a northeastern border region but also for being a gateway to the Seven Sister States. Peripheral development of Siliguri Corridor is one of the reasons for illegal practices like smuggling and terrorism. In year 2002 Nepal, Bhutan and Bangladesh discussed a proposal to form a free trade corridor to simplify the goods transportation through Siliguri Corridor but no such pact could be concluded that would have avoided the activities like smuggling and terrorism mainly through economic and diplomatic ventures.

  12. Deep-tow magnetic survey above large exhumed mantle domains of the eastern Southwest Indian ridge

    Science.gov (United States)

    Bronner, A.; Munschy, M.; Carlut, J. H.; Searle, R. C.; Sauter, D.; Cannat, M.

    2011-12-01

    The recent discovery of a new type of seafloor, the "smooth seafloor", formed with no or very little volcanic activity along the ultra-slow spreading Southwest Indian ridge (SWIR) shows an unexpected complexity in processes of generation of the oceanic lithosphere. There, detachment faulting is thought to be a mechanism for efficient exhumation of deep-seated mantle rocks. We present here a deep-tow geological-geophysical survey over smooth seafloor at the eastern SWIR (62-64°N) combining magnetic data, geology mapping from side-scan sonar images and results from dredge sampling. We introduce a new type of calibration approach for deep-tow fluxgate magnetometer. We show that magnetic data can be corrected from the magnetic effect of the vehicle with no recourse to its attitude (pitch, roll and heading) but only using the 3 components recorded by the magnetometer and an approximation of the scalar intensity of the Earth magnetic field. The collected dredge samples as well as the side-scan images confirm the presence of large areas of exhumed mantle-derived peridodites surrounded by a few volcanic constructions. This allows us to hypothesis that magnetic anomalies are caused by serpentinized peridotites or magmatic intrusions. We show that the magnetic signature of the smooth seafloor is clearly weaker than the surrounding volcanic areas. Moreover, the calculated magnetization of a source layer as well as the comparison between deep-tow and sea-surface magnetic data argue for strong East-West variability in the distribution of the magnetized sources. This variability may results from fluid-rocks interaction along the detachment faults as well as from the repartition of the volcanic material and thus questions the seafloor spreading origin of the corresponding magnetic anomalies. Finally, we provide magnetic arguments, as calculation of block rotation or spreading asymmetry in order to better constrain tectonic mechanisms that occur during the formation of this

  13. Urban agglomerations in the function of regional integration of Serbia in South-Eastern Europe

    Directory of Open Access Journals (Sweden)

    Tošić Dragutin

    2005-01-01

    Full Text Available In this article is analyzed the importance of urban agglomerations in the regional organization of Serbian space at one side, and on the other side they are taken as carriers of the future integration of the Serbian urban system into the urban of the South-Eastern Europe (SEE. In the regional configuration of Serbia, more different forms of territorial impacts of urbanization, urban areas and urban regions. High level of urban centralization is formed under the influence of the population density and functions of the metropolitan area of Belgrade. The problems of unbalanced disposition of population growth and qualitative transformation of urban centers are stressed and analyzed. Based on the role in integration process in the SEE, the metropolitan region of Belgrade is pointed out as its principal carrier and the metropolitan region of Niš as its secondary carrier, as well as the urban centers of importance for the cross-border regional cooperation. As the most suitable instrument of internal regional integration the model of Functional Urban Regions (FURs or Functional Urban Areas (FUAs is proposed, and for external regional integration is proposed the model of Metropolitan European Growth Areas (MEGAs. The coherent short-term and long-term development strategies for Serbian towns and their regions seem absent.

  14. The great triangular seismic region in eastern Asia: Thoughts on its dynamic context

    Directory of Open Access Journals (Sweden)

    Xianglin Gao

    2011-01-01

    Full Text Available A huge triangle-shaped tectonic region in eastern Asia plays host to numerous major earthquakes. The three boundaries of this region, which contains plateaus, mountains, and intermountain basins, are roughly the Himalayan arc, the Tianshan-Baikal, and longitude line ∼105°E. Within this triangular region, tectonism is intense and major deformation occurs both between crustal blocks and within most of them. Outside of this region, rigid blocks move as a whole with relatively few major earthquakes and relatively weak Cenozoic deformation. On a large tectonic scale, the presence of this broad region of intraplate deformation results from dynamic interactions between the Indian, Philippine Sea-West Pacific, and Eurasian plates, as well as the influence of deep-level mantle flow. The Indian subcontinent, which continues to move northwards at ∼40 mm/a since its collision with Eurasia, has plunged beneath Tibet, resulting in various movements and deformations along the Himalayan arc that diffuse over a long distance into the hinterland of Asia. The northward crustal escape of Asia from the Himalayan collisional zone turns eastwards and southeastwards along 95°–100°E longitude and defines the eastern Himalayan syntaxis. At the western Himalayan syntaxis, the Pamirs continue to move into central Asia, leading to crustal deformation and earthquakes that are largely accommodated by old EW or NW trending faults in the bordering areas between China, Mongolia, and Russia, and are restricted by the stable landmass northwest of the Tianshan-Altai-Baikal region. The subduction of the Philippine and Pacific plates under the Eurasian continent has generated a very long and narrow seismic zone along trenches and island arcs in the marginal seas while imposing only slight horizontal compression on the Asian continent that does not impede the eastward motion of eastern Asia. In the third dimension, there may be southeastward deep mantle flow beneath most of

  15. Changing the cubic ferrimagnetic domain structure in temperature region of spin flip transition

    International Nuclear Information System (INIS)

    Djuraev, D.R.; Niyazov, L.N.; Saidov, K.S.; Sokolov, B.Yu.

    2011-01-01

    The transformation of cubic ferrimagnetic Tb 0.2 Y 2.8 Fe 5 O 12 domain structure has been studied by magneto optic method in the temperature region of spontaneous spin flip phase transition (SPT). It has been found that SPT occurs in a finite temperature interval where the coexistence of low- and high- temperature magnetic phase domains has observed. A character of domain structure evolution in temperature region of spin flip essentially depends on the presence of mechanical stresses in crystal. Interpretation of experimental results has been carried out within the framework of SPT theory for a cubic crystal. (authors)

  16. Implementation of the International Code of Marketing of Breastmilk Substitutes in the Eastern Mediterranean Region.

    Science.gov (United States)

    Al Jawaldeh, Ayoub; Sayed, Ghada

    2018-04-05

    Optimal breastfeeding practices and appropriate complementary feeding improve child health, survival and development. The countries of the Eastern Mediterranean Region have made significant strides in formulation and implementation of legislation to protect and promote breastfeeding based on The International Code of Marketing of Breast-milk Substitutes (the Code) and subsequent relevant World Health Assembly resolutions. To assess the implementation of the Code in the Region. Assessment was conducted by the World Health Organization (WHO) Regional Office for the Eastern Mediterranean using a WHO standard questionnaire. Seventeen countries in the Region have enacted legislation to protect breastfeeding. Only 6 countries have comprehensive legislation or other legal measures reflecting all or most provisions of the Code; 4 countries have legal measures incorporating many provisions of the Code; 7 countries have legal measures that contain a few provisions of the Code; 4 countries are currently studying the issue; and only 1 country has no measures in place. Further analysis of the legislation found that the text of articles in the laws fully reflected the Code articles in only 6 countries. Most countries need to revisit and amend existing national legislation to implement fully the Code and relevant World Health Assembly resolutions, supported by systematic monitoring and reporting. Copyright © World Health Organization (WHO) 2018. Some rights reserved. This work is available under the CC BY-NC-SA 3.0 IGO license (https://creativecommons.org/licenses/by-nc-sa/3.0/igo).

  17. Hospital management training for the Eastern Mediterranean Region: time for a change?

    Science.gov (United States)

    Rabbani, Fauziah; Hashmani, Farah Naz; Mukhi, Aftab A Ali; Gul, Xaher; Pradhan, Nousheen; Hatcher, Peter; Farag, Mounir; Abbas, Farhat

    2015-01-01

    The WHO Eastern Mediterranean Regional Office has emphasized health system strengthening among the top five strategic priorities. One of the integral elements of health systems are the hospitals. The purpose of this paper is to review the need for formalized training in hospital management to improve the quality of care. Literature review and hands on experience of conducting a regional training in hospital management for Eastern Mediterranean Region (EMR) countries. Majority of patients in EMR bypass Primary Health Care facilities due to inadequate quality of services and prefer seeking specialized care at a tertiary level. There is mounting evidence of mediocre to poor patient satisfaction due to inefficient health care practices in hospitals of EMR. Strengthening the management capacity of the hospitals through a formal training programme is therefore necessary for improving the performance of health care delivery and the overall health system. Hospital management encompasses hospital planning and operational activities including development and implementation of organizational strategies to ensure adequate numbers and quality of trained human resources and effective financial management, disaster management, health management information system utilization, support services, biomedical engineering, transport and waste management. Such training will prepare health care professionals with leadership skills to deliver quality hospital services. This is one of the first papers emphasizing the need for a formal structured regional training in hospital management for the countries of EMR. A modular incremental training approach developing an EMR Credit Transfer and Accumulation system is proposed.

  18. Deep-tow geophysical survey above large exhumed mantle domains of the eastern Southwest Indian ridge

    Science.gov (United States)

    Bronner, A.; Munschy, M.; Sauter, D.; Carlut, J.; Searle, R.; Cannat, M.

    2012-04-01

    The recent discovery of a new type of seafloor, the "smooth seafloor", formed with no or very little volcanic activity along the easternmost part of the ultra-slow spreading Southwest Indian ridge (SWIR) shows an unexpected complexity in processes of generation of the oceanic lithosphere. There, detachment faulting is thought to be a mechanism for efficient exhumation of deep-seated mantle rocks. We present here a deep-tow geological-geophysical survey over smooth seafloor at the eastern SWIR (62-64°N) combining multibeam bathymetric data, magnetic data, geology mapping from sidescan sonar (TOBI) images and results from dredge sampling. We introduce a new type of calibration approach for deep-tow fluxgate magnetometer. We show that magnetic data can be corrected from the magnetic effect of the vehicle with no recourse to its attitude (pitch, roll and heading) but only using the 3 components recorded by the magnetometer and an approximation of the scalar intensity of the Earth magnetic field. The collected dredge samples as well as the sidescan sonar images confirm the presence of large areas of exhumed mantle-derived peridodites surrounded by a few volcanic constructions. We investigate the possibility that magnetic anomalies are either caused by serpentinized peridotites and/or magmatic intrusions. We show that the magnetic signature of the smooth seafloor is clearly weaker than the surrounding volcanic areas. Moreover, the calculated magnetization of a source layer as well as the comparison between deep-tow and sea-surface magnetic data argue for strong East-West variability in the distribution of the magnetized sources. This variability may result from fluid-rock interactions along the detachment faults as well as from the occurrence of small sized and thin volcanic patches and thus questions the seafloor spreading origin of the corresponding magnetic anomalies. Finally, we provide magnetic arguments, as calculation of block rotation or spreading asymmetry in

  19. The Formation of the Eastern Africa Rabies Network: A Sub-Regional Approach to Rabies Elimination.

    Science.gov (United States)

    Pieracci, Emily G; Scott, Terence P; Coetzer, Andre; Athman, Mwatondo; Mutembei, Arithi; Kidane, Abraham Haile; Bekele, Meseret; Ayalew, Girma; Ntegeyibizaza, Samson; Assenga, Justine; Markalio, Godson; Munyua, Peninah; Nel, Louis H; Blanton, Jesse

    2017-01-01

    International rabies networks have been formed in many of the canine-rabies endemic regions around the world to create unified and directed regional approaches towards elimination. The aim of the first sub-regional Eastern Africa rabies network meeting, which included Kenya, Ethiopia, Tanzania, Rwanda, and Uganda, was to discuss how individual country strategies could be coordinated to address the unique challenges that are faced within the network. The Stepwise Approach towards Rabies Elimination and the Global Dog Rabies Elimination Pathway tool were used to stimulate discussion and planning to achieve the elimination of canine-mediated human rabies by 2030. Our analysis estimated a total dog population of 18.3 million dogs in the Eastern Africa region. The current dog vaccination coverage was estimated to be approximately 5% (915,000 dogs), with an estimated 4910 vaccinators available. Assuming that every vaccinator performs rabies vaccination, this equated to each vaccinator currently vaccinating 186 dogs per year, whilst the target would be to vaccinate 2609 dogs every year for the community to reach 70% coverage. In order to achieve the World Health Organization-recommended 70% vaccination coverage, an additional 11 million dogs need to be vaccinated each year, pointing to an average annual shortfall of $ 23 million USD in current spending to achieve elimination by 2030 across the region. Improved vaccination efficiency within the region could be achieved by improving logistics and/or incorporating multiple vaccination methods to increase vaccinator efficiency, and could serve to reduce the financial burden associated with rabies elimination. Regional approaches to rabies control are of value, as neighboring countries can share their unique challenges while, at the same time, common approaches can be developed and resource-saving strategies can be implemented.

  20. The prevalence and distribution of Argas walkerae (Acari: Argasidae in the eastern region of the Eastern Cape Province, South Africa : research communications

    Directory of Open Access Journals (Sweden)

    N. Nyangiwe

    2008-09-01

    Full Text Available The prevalence and geographic distribution of the fowl tampan, Argas walkerae Kaiser & Hoogstraal, 1969 was determined in the eastern region of the Eastern Cape Province, South Africa by inspecting two fowl houses in the vicinity of each of 72 randomly selected communal cattle dip-tanks. Tampans were collected from 102 (70.8 % of the 144 fowl houses in the neighbourhood of 57 (79.2 % of the 72 selected dip-tanks, and the localities of the collections were mapped. Argas walkerae was present in fowl houses from the warm coastal regions of the Indian Ocean in the south to the cold and mountainous Drakensberg in the north-east of the Province. Taking into account the probable sensitivity of the sampling method, it is estimated that A. walkerae is likely to be present in fowl houses belonging to between 74 and 84 % of communities making use of cattle dip-tanks in the eastern region of the Eastern Cape Province, and that when it is present, between 64 and 75 % of fowl houses will be infested. The geographic distribution of A. walkerae seemed to be more strongly associated with the presence of fowls and fowl houses containing raw or processed wood in their structure than with climate.

  1. A numerical modelling study on regional mercury budget for eastern North America

    Directory of Open Access Journals (Sweden)

    X. Lin

    2003-01-01

    Full Text Available In this study, we have integrated an up-to-date physio-chemical transformation mechanism of Hg into the framework of US EPA's CMAQ model system. In addition, the model adapted detailed calculations of the air-surface exchange for Hg to properly describe Hg re-emissions and dry deposition from and to natural surfaces. The mechanism covers Hg in three categories, elemental Hg (Hg0, reactive gaseous Hg (RGM and particulate Hg (HgP. With interfacing to MM5 (meteorology processor and SMOKE (emission processor, we applied the model to a 4-week period in June/July 1995 on a domain covering most of eastern North America. Results indicate that the model simulates reasonably well the levels of total gaseous Hg (TGM and the specific Hg wet deposition measurements made by the Hg deposition network (MDN. Moreover, results from various scenario runs reveal that the Hg system behaves in a closely linear way in terms of contributions from different source categories, i.e. anthropogenic emissions, natural re-emissions and background. Analyses of the scenario results suggest that 37% of anthropogenically emitted Hg was deposited back in the model domain with 5155 kg of anthropogenic Hg moving out of the domain during the simulation period. Overall, the domain served as a net source, which supplied ~a half ton of Hg to the global background pool over the period. Our model validation and a sensitivity test further rationalized the rate constant for gaseous oxidation of Hg0 by hydroxyl radical OH used in the global scale modelling study by Bergan and Rodhe (2001. A further laboratory determination of the reaction rate constant, including its temperature dependence, stands as one of the important issues critical to improving our knowledge on the budget and cycling of Hg.

  2. Solute geochemistry of the Snake River Plain regional aquifer system, Idaho and eastern Oregon

    International Nuclear Information System (INIS)

    Wood, W.W.; Low, W.H.

    1987-01-01

    Three geochemical methods were used to determine chemical reactions that control solute concentrations in the Snake River Plain regional aquifer system: (1) calculation of a regional solute balance within the aquifer and of mineralogy in the aquifer framework to identify solute reactions, (2) comparison of thermodynamic mineral saturation indices with plausible solute reactions, and (3) comparison of stable isotope ratios of the groundwater with those in the aquifer framework. The geothermal groundwater system underlying the main aquifer system was examined by calculating thermodynamic mineral saturation indices, stable isotope ratios of geothermal water, geothermometry, and radiocarbon dating. Water budgets, hydrologic arguments, and isotopic analyses for the eastern Snake River Plain aquifer system demonstrate that most, if not all, water is of local meteoric and not juvenile or formation origin. Solute balance, isotopic, mineralogic, and thermodynamic arguments suggest that about 20% of the solutes are derived from reactions with rocks forming the aquifer framework. Reactions controlling solutes in the western Snake river basin are believed to be similar to those in the eastern basin but the regional geothermal system that underlies the Snake river Plain contains total dissolved solids similar to those in the overlying Snake River Plain aquifer system but contains higher concentrations of sodium, bicarbonate, silica, fluoride, sulfate, chloride, arsenic, boron, and lithium, and lower concentrations of calcium, magnesium, and hydrogen. 132 refs., 30 figs., 27 tabs

  3. Technical Efficiency Analysis of Container Terminals in the Middle Eastern Region

    Directory of Open Access Journals (Sweden)

    Ebrahim Sharaf Almawsheki

    2015-12-01

    Full Text Available Despite an increasing number of studies on the efficiency of container terminals, their focus has mostly been on advanced and emerging markets. There are limited studies on container terminals in developing countries such as those of the Middle Eastern region, which are located in a critical geographic position in the international maritime route between the East and the West. Information on their potential for development relative to other terminals worldwide is thus not readily available. This study aims to evaluate the technical efficiency of 19 container terminals in the Middle Eastern region. The DEA approach is used to measure technical efficiency, and slack variable analysis identifies potential areas of improvement for inefficient terminals. The results show that the Jebel Ali, Salalah and Beirut container terminals are the most efficient terminals in the region, and that the least efficient is the terminal in Aden. The results provide valuable information for terminal managers, helping to develop resource utilisation for steady development in operational efficiency.

  4. Moment Magnitude Calibration for the Eastern Mediterranean Region from Broadband Regional Coda Envelopes

    Energy Technology Data Exchange (ETDEWEB)

    Mayeda, K; Eken, T; Hofstetter, A; Turkelli, N; O' Boyle, J; Orgulu, G; Gok, R

    2003-07-17

    The following is an overview of results from ROA01-32 that focuses on an empirical method of calibrating stable seismic source moment-rate spectra derived from regional coda envelopes using broadband stations. The main goal was to develop a regional magnitude methodology that had the following properties: (1) it is tied to an absolute scale and is thus unbiased and transportable; (2) it can be tied seamlessly to the well-established teleseismic and regional catalogs; (3) it is applicable to small events using a sparse network of regional stations; (4) it is flexible enough to utilize S{sub n}-coda, L{sub g}-coda, or P-coda, whichever phase has the best signal-to-noise ratio. The results of this calibration yield source spectra and derived magnitudes that were more stable than any other direct-phase measure to date. Our empirical procedure accounted for all propagation, site, and S-to-coda transfer function effects. The resultant coda-derived moment-rate spectra were used to provide traditional band-limited magnitude (e.g., M{sub L}, m{sub b} etc.) as well as an unbiased, unsaturated magnitude (moment magnitude, M{sub w}) that is tied to a physical measure of earthquake size (i.e., seismic moment). We validated our results by comparing our coda-derived moment estimates with those obtained from long-period waveform modeling. We first tested and validated the method using events distributed along the Dead Sea Rift (e.g., Mayeda et al., 2003). Next, we tested the transportability of the method to earthquakes distributed across the entire country of Turkey and validated our results using seismic moments of over 50 events that had been previously waveform modeled using the method of Dreger and Helmberger, (1993). In both regions we demonstrated that the interstation magnitude scatter was significantly reduced when using the coda-based magnitudes (i.e., M{sub w}(coda) and m{sub b}(coda)). Once calibrated, the coda-derived source spectra provided stable, unbiased magnitude

  5. Chapter 4: Regional magnetic domains of the Circum-Arctic: A framework for geodynamic interpretation

    Science.gov (United States)

    Saltus, R.W.; Miller, E.L.; Gaina, C.; Brown, P.J.

    2011-01-01

    We identify and discuss 57 magnetic anomaly pattern domains spanning the Circum-Arctic. The domains are based on analysis of a new Circum-Arctic data compilation. The magnetic anomaly patterns can be broadly related to general geodynamic classification of the crust into stable, deformed (magnetic and nonmagnetic), deep magnetic high, oceanic and large igneous province domains. We compare the magnetic domains with topography/bathymetry, regional geology, regional free air gravity anomalies and estimates of the relative magnetic 'thickness' of the crust. Most of the domains and their geodynamic classification assignments are consistent with their topographic/bathymetric and geological expression. A few of the domains are potentially controversial. For example, the extent of the Iceland Faroe large igneous province as identified by magnetic anomalies may disagree with other definitions for this feature. Also the lack of definitive magnetic expression of oceanic crust in Baffin Bay, the Norwegian-Greenland Sea and the Amerasian Basin is at odds with some previous interpretations. The magnetic domains and their boundaries provide clues for tectonic models and boundaries within this poorly understood portion of the globe. ?? 2011 The Geological Society of London.

  6. Irradiation of ready-to-eat foods at USDA'S Eastern Regional Reasearch Center - 2003 update

    International Nuclear Information System (INIS)

    Sommers, Christopher; Fan Xuetong; Niemira, Brendan; Rajkowski, Kathleen

    2004-01-01

    Ionizing radiation is a safe and effective method for eliminating bacterial pathogens from food products and disinfestation of fruits and vegetables. Since 1980 research has been conducted at USDA's Eastern Regional Research Center pertaining to the elimination of food-borne pathogens from meat, poultry, fruit and vegetable products. Recent work has focused on elimination of pathogens such as Escherichia coli O157:H7, Salmonella spp., and Listeria monocytogenes from ready-to-eat (RTE) food products including hot dogs, bologna, lettuce, cilantro, sprouts and seeds, and frozen vegetables. The ionizing radiation dose required to eliminate those pathogens from RTE foods has been found to be commodity, formulation and temperature dependent. The need to eliminate bacterial pathogens from RTE food products must always be balanced with the maintenance of product quality. In addition to determining the effective ionizing radiation doses required for pathogen elimination the effects of irradiation on product chemistry, nutritional value and organoleptic quality have also been determined. A review of the studies conducted at USDA's Eastern Regional Research Center in 2002 and 2003 is presented in this article

  7. Lithospheric flexural strength and effective elastic thicknesses of the Eastern Anatolia (Turkey) and surrounding region

    Science.gov (United States)

    Oruç, Bülent; Gomez-Ortiz, David; Petit, Carole

    2017-12-01

    The Lithospheric structure of Eastern Anatolia and the surrounding region, including the northern part of the Arabian platform is investigated via the analysis and modeling of Bouguer anomalies from the Earth Gravitational Model EGM08. The effective elastic thickness of the lithosphere (EET) that corresponds to the mechanical cores of the crust and lithospheric mantle is determined from the spectral coherence between Bouguer anomalies and surface elevation data. Its average value is 18.7 km. From the logarithmic amplitude spectra of Bouguer anomalies, average depths of the lithosphere-asthenosphere boundary (LAB), Moho, Conrad and basement in the study area are constrained at 84 km, 39 km, 16 km and 7 km, respectively. The geometries of the LAB and Moho are then estimated using the Parker-Oldenburg inversion algorithm. We also present a lithospheric strength map obtained from the spatial variations of EET determined by Yield Stress Envelopes (YSE). The EET varies in the range of 12-23 km, which is in good agreement with the average value obtained from spectral analysis. Low EET values are interpreted as resulting from thermal and flexural lithospheric weakening. According to the lithospheric strength of the Eastern Anatolian region, the rheology model consists of a strong but brittle upper crust, a weak and ductile lower crust, and a weak lower part of the lithosphere. On the other hand, lithosphere strength corresponds to weak and ductile lower crust, a strong upper crust and a strong uppermost lithospheric mantle for the northern part of the Arabian platform.

  8. Irradiation of ready-to-eat foods at USDA'S Eastern Regional Reasearch Center-2003 update

    Science.gov (United States)

    Sommers, Christopher; Fan, Xuetong; Niemira, Brendan; Rajkowski, Kathleen

    2004-09-01

    Ionizing radiation is a safe and effective method for eliminating bacterial pathogens from food products and disinfestation of fruits and vegetables. Since 1980 research has been conducted at USDA's Eastern Regional Research Center pertaining to the elimination of food-borne pathogens from meat, poultry, fruit and vegetable products. Recent work has focused on elimination of pathogens such as Escherichia coli O157:H7, Salmonella spp., and Listeria monocytogenes from ready-to-eat (RTE) food products including hot dogs, bologna, lettuce, cilantro, sprouts and seeds, and frozen vegetables. The ionizing radiation dose required to eliminate those pathogens from RTE foods has been found to be commodity, formulation and temperature dependent. The need to eliminate bacterial pathogens from RTE food products must always be balanced with the maintenance of product quality. In addition to determining the effective ionizing radiation doses required for pathogen elimination the effects of irradiation on product chemistry, nutritional value and organoleptic quality have also been determined. A review of the studies conducted at USDA's Eastern Regional Research Center in 2002 and 2003 is presented in this article.

  9. Thinning trials in lowland plantations in the Veneto Region (North-eastern Italy

    Directory of Open Access Journals (Sweden)

    Mario Pividori

    2014-06-01

    Full Text Available Thinning trials in lowland plantations in the Veneto Region (North-eastern Italy. More than 234 hectares of new plantations of lowland mixed forest have been realized in the last 20 years in the Veneto Region (North-eastern Italy. In many of these is now needed to start thinning operations, but there is a lack of experience about this topic. Aim of this work was to undertake an experimentation on different types of thinnings. The thinning trial has been performed at Bosco San Marco forest, municipality of Cessalto (Venice, in a very dense hornbeam-oak plantation aged 16. In 2010, three different thinning types were implemented on 9 hectares according to the following layout: geometrical (34% of woody mass removed, selective (15%, mixed geometrical-selective (30%, control plot. Three years later no significant differences between thinning trials in term of diametric growth, geometrical thinning excepted, were observed. These results provide a suite of solutions to the forest manager for choosing the early thinning type in high tree density condition.

  10. Strong states in a troubled region: anatomies of a Middle Eastern regional conflict formation

    NARCIS (Netherlands)

    Leenders, R.; Harpviken, K.B.

    2010-01-01

    This article calls for closer attention to the Middle East in the wider debate on the purported rise of new modes of armed conflict following the end of the Cold War, particularly in relation to the notion of ‘regional conflict formations’ (RCFs). In so doing, it presents and analyses three main

  11. Multidimensional Mantle Convection Models in Eastern Anatolia, the North Arabian Platform, and Caucasus Region

    Science.gov (United States)

    Sengul Uluocak, E.; Shahnas, H.; Pysklywec, R.; Gogus, O.; Eken, T.

    2017-12-01

    Eastern Anatolia, the North Arabian Platform, and Caucasus regions show many features of collisional tectonics with different convergence rates and shortening from south to north. The volcanism, sediment provenience, and thermochronological data suggest that the shortening and exhumation in the Greater Caucasus started during the Eocene-Oligocene synchronously with the collision between Arabia-Bitlis-Pötürge Massif in the south. Previous works indicate that the uplift (up to 2 km) in Eastern Anatolia related to upwelling mantle following the deformation of the Arabian oceanic lithosphere ( 11 Ma) during the ongoing Greater Caucasus closure is the dominant tectonic processes in the center of the region. However, there is no integrated geodynamic model that explains the deformation mechanisms of the region -and their possible interactions with each other -under the dynamic forces. In this study, we use multidimensional mantle-lithosphere convection/deformation models to quantify the geodynamic processes as constrained by the geological/geophysical observations in the region. For the models, seismic studies provide the high-resolution images of the upwelling mantle beneath Eastern Anatolia and the presence -and the locations- of the seismically fast structures associated with the relic/subducted slabs at varying depths such as the Bitlis slab in the south, and the Pontide and Kura slabs in the north. Fast polarization directions observed from splitting analyses exhibit an overall NE-SW oriented mantle anisotropy and a comparison between Pn and SKS derived fast wave azimuths indicates a crust-mantle coupling most likely implying vertically coherent deformation to the north of the study area. For the geodynamic models, we modify the mantle and lithosphere rheology as well as the thermal state. We interpret the estimated uplift and subsidence anomalies related to lithospheric variations (ranging from 54 km to 211 km) and subducting slab behavior with observed

  12. Public perception on forestry issues in the Region of Valencia (Eastern Spain): diverging from policy makers

    Energy Technology Data Exchange (ETDEWEB)

    Fabra-Crespo, M.; Mola-Yudego, B.; Gritten, D.; Rojas-Briales, E.

    2012-11-01

    Are the policies designed by decision-makers differing from society's wishes and preferences. The present paper analyzes the divergences between forest policy and public opinion in the Region of Valencia (Comunidad Valenciana) in Eastern Spain. The data is based on an extensive telephone survey of the general public on their perception of forestry issues. The issues studied include attitudes regarding forest fires, silvicultural treatments, the externalise produced by forest owners, and the state forest services role related to these issues. In total, the answers of 823 respondents were analyzed using classification trees. The results of the analysis showed a large divergence between the desires, preferences and priorities of society, on the one hand, and the policies implemented by the regional government, on the other. The study concludes that communication strategies concerning sustainable forest management need to be further developed by the responsible authorities, with the input of the research community. (Author) 53 refs.

  13. Preliminary Regional Analysis of the Kaguya Lunar Radar Sounder (LRS) Data through Eastern Mare Imbrium

    Science.gov (United States)

    Cooper, B.L.; Antonenko, I.; Yamaguchi, Y.; Osinski, G.; Ono, T.; Ku-mamoto, A.

    2009-01-01

    The Lunar Radar Sounder (LRS) experiment on board the Kaguya spacecraft is observing the subsurface structure of the Moon, using ground-penetrating radar operating in the frequency range of 5 MHz [1]. Because LRS data provides in-formation about lunar features below the surface, it allows us to improve our understanding of the processes that formed the Moon, and the post-formation changes that have occurred (such as basin formation and volcanism). We look at a swath of preliminary LRS data, that spans from 7 to 72 N, and from 2 to 10 W, passing through the eastern portion of Mare Imbrium (Figure 1). Using software, designed for the mineral exploration industry, we produce a preliminary, coarse 3D model, showing the regional structure beneath the study area. Future research will involve smaller subsets of the data in regions of interest, where finer structures, such as those identified in [2], can be studied.

  14. Regional polyphase deformation of the Eastern Sierras Pampeanas (Argentina Andean foreland): strengths and weaknesses of paleostress inversion

    Science.gov (United States)

    Traforti, Anna; Zampieri, Dario; Massironi, Matteo; Viola, Giulio; Alvarado, Patricia; Di Toro, Giulio

    2016-04-01

    oriented WSW-ENE). Although remarkable differences in reactivation mechanisms have been observed for the various studied lithological domains (schist, gneiss and granitic rocks), the brittle regional polyphase deformation of the Eastern Sierras Pampeanas appears to be dominated by two extensional episodes (σ3 oriented NE/ENE and WNW, respectively), which can be associated with Middle-Late Permian to Early Cretaceous tectonism, followed by a compressional paleostress (σ1 oriented ENE), which is compatible with the present day Andean convergence. Paleostress inversion techniques, despite all uncertainties involved, represent a robust approach to disentangle complex polyphase deformation histories both in term of reactivation mechanisms and strain partitioning. References: Bense, F. A., Wemmer, K., Löbens, S., & Siegesmund, S. (2013). Fault gouge analyses: K-Ar illite dating, clay mineralogy and tectonic significance-a study from the Sierras Pampeanas, Argentina. International Journal of Earth Sciences, 103, 189-218. Martino, R. D. (2003). Las fajas de deformación dúctil de las Sierras Pampeanas de Córdoba : Una reseña general. Revista de La Asociación Geológica Argentina, 58(4), 549-571. Ramos, V. A., Cristallini, E. O., & Perez, D. J. (2002). The Pampean flat-slab of the Central Andes. Journal of South American Earth Sciences, 15, 59-78.

  15. Bathymetric and regional changes in benthic macrofaunal assemblages on the deep Eastern Brazilian margin, SW Atlantic

    Science.gov (United States)

    Bernardino, Angelo Fraga; Berenguer, Vanessa; Ribeiro-Ferreira, Venina P.

    2016-05-01

    Deep-sea continental slopes have valuable mineral and biological resources in close proximity to diverse, undersampled and fragile marine benthic ecosystems. The eastern Brazilian Continental Margin (19.01°S to 21.06°S, 37.88°W to 40.22°W) is an important economic region for both fishing and oil industries, but is poorly understood with respect to the structure of the soft-sediment benthic fauna, their regional distribution and their bathymetric patterns. To identify spatial and temporal patterns of benthic macrofaunal assemblages on the slope (400 to 3000 m), the Espirito Santo Basin Assessment Project (AMBES, coordinated by Cenpes-Petrobras) sampled 42 stations across the Brazilian Eastern Slope during both Summer 2012 and Winter 2013. We found a significant decrease in macrofaunal abundance at the 400 m isobath along the slope near the northern region of the Espirito Santo Basin, suggesting benthic responses to upwelling events towards the south in Campos Basin and southern Espirito Santo Basin. The taxonomic diversity and assemblage composition also changed significantly across depth zones with mid-slope peaks of diversity at 1000-1300 m. In general, macrofaunal assemblages were strongly related to slope depth, suggesting a strong influence of productivity gradients and water mass distribution on this oligotrophic margin. Sediment grain size was marginally important to macrofaunal composition on the upper slope. In general, macrofaunal assemblages on the slope of Espirito Santo Basin are similar to other areas of the SE Brazilian margin, but regional changes in response to productivity and depth need to be considered for management strategies in the face of increasing economic activities off-shore.

  16. Regional aspects of long-term public sector psychiatric care in the Eastern Cape

    Directory of Open Access Journals (Sweden)

    Kiran Sukeri

    2017-05-01

    Full Text Available Objectives: The objective of this research was to determine regional aspects (such as clinical, geographic and socio-demographic influencing the use of public sector long-term psychiatric services in the Eastern Cape. This is important in improving service delivery, to assist policy developers with evidence-based research and in providing equitable and efficient resource utilisation. Methodology: A situational analysis of Tower Psychiatric Hospital and Psychosocial Rehabilitation Centre (TPHPRC in the Eastern Cape was conducted. Patient administrative data were utilised to determine geographic origin, date and age at admission, gender and diagnosis as of December 2015. The number of admissions from each region for the years 2010–2015 was also extracted from these data. Results: As of December 2015, there were a total of 390 patients at TPHPRC. Of these, 87% were male patients. The average age at admission for male and female patients was 36 years and 44 years, respectively. Of the patients, 53% originated from the western regions and 57% of female patients presented with a dual diagnosis. The highest number of admissions was in 2015, with the majority originating from Port Elizabeth. Conclusion: Despite higher access to public psychiatric care in the western region, the majority of patients originated from there. Contributing factors to this include diagnoses, insufficient bed numbers and the absence of admission criteria and referral pathways. It is recommended that the provincial Department of Health set up a task team to determine a standardised working framework for all public sector psychiatric institutions. This should be informed by national policies, legislation and provincial norms and indicators.

  17. Typomorphic Characteristics of Molybdenite from the Bystrinsky Cu-Au Porphyry-Skarn Deposit, Eastern Transbaikal Region, Russia

    Science.gov (United States)

    Kovalenker, V. A.; Trubkin, N. V.; Abramova, V. D.; Plotinskaya, O. Yu.; Kiseleva, G. D.; Borisovskii, S. E.; Yazykova, Yu. I.

    2018-01-01

    The paper presents pioneering data on the composition, texture, and crystal structure of molybdenite from various types of molybdenum mineralization at the Bystrinsky Cu-Au-Fe porphyry-skarn deposit in the eastern Transbaikal region, Russia. The data were obtained using electron microprobe analysis (EMPA), laser ablation-inductively coupled plasma mass spectrometry (LA-ICP-MS), and high-resolution transmission electron microscopy (HRTEM). Molybdenite found at the deposit in skarn, sulfide-poor quartz veins, and quartz-feldspar alteration markedly differs in the concentrations of trace elements determined by their species in the mineral, as well as in its structural features. Molybdenite-2H from skarn associated with phyllosilicates occurs as ultrafine crystals with uniform shape and texture; no dislocations or inclusions were found but amorphous silica was. The molybdenite composition is highly contrasting in the content and distribution of both structure-related (Re, W, and Se) and other (Mn, Co, Ni, Cu, Zn, As, Ag, Cd, Sb, Te, Ag, Pd, Au, Hg, Pb, and Bi) metals. In the sulfide-poor quartz veins, highly structurally heterogeneous (2H + 3R) molybdenite microcrystals with abundant defects (dislocations and volumetrically distributed inclusions) are associated with illite, goethite, and barite. Some single crystals are unique three-phase (2H + 3R polytypes + amorphous MoS2). The mineral has a low concentration of all trace elements, which are uniformly distributed. However, individual domains with uniquely high Pd, Te, Ni, Hg, and W concentrations caused by mineral inclusions are found in some grains. Molybdenite from quartz-feldspar alteration is characterized by low concentrations of all trace elements except for Re and Se, which enrich some domains of the grains. Our data indicate that the compositional and structural heterogeneity of molybdenite from the Bystrinsky deposit are its crucial features, which obviously correlate with the types of Mo mineralization.

  18. Gender Role Attitudes among Higher Education Students in a Borderland Central-Eastern European Region Called "Partium"

    Science.gov (United States)

    Fényes, Hajnalka

    2014-01-01

    In this paper, we examine the attitudes towards gender roles among higher education students in a borderland Central-Eastern European region. We used the database of "The Impact of Tertiary Education on Regional Development" project (N = 602, 2010). We intend to determine what kind of attitudes towards gender roles the students identify…

  19. Modeling regional initiation of rainfall-induced shallow landslides in the eastern Umbria Region of central Italy

    Science.gov (United States)

    Salciarini, D.; Godt, J.W.; Savage, W.Z.; Conversini, P.; Baum, R.L.; Michael, J.A.

    2006-01-01

    We model the rainfall-induced initiation of shallow landslides over a broad region using a deterministic approach, the Transient Rainfall Infiltration and Grid-based Slope-stability (TRIGRS) model that couples an infinite-slope stability analysis with a one-dimensional analytical solution for transient pore pressure response to rainfall infiltration. This model permits the evaluation of regional shallow landslide susceptibility in a Geographic Information System framework, and we use it to analyze susceptibility to shallow landslides in an area in the eastern Umbria Region of central Italy. As shown on a landslide inventory map produced by the Italian National Research Council, the area has been affected in the past by shallow landslides, many of which have transformed into debris flows. Input data for the TRIGRS model include time-varying rainfall, topographic slope, colluvial thickness, initial water table depth, and material strength and hydraulic properties. Because of a paucity of input data, we focus on parametric analyses to calibrate and test the model and show the effect of variation in material properties and initial water table conditions on the distribution of simulated instability in the study area in response to realistic rainfall. Comparing the results with the shallow landslide inventory map, we find more than 80% agreement between predicted shallow landslide susceptibility and the inventory, despite the paucity of input data.

  20. Spatial distribution and occurrence probability of regional new particle formation events in eastern China

    Directory of Open Access Journals (Sweden)

    X. Shen

    2018-01-01

    Full Text Available In this work, the spatial extent of new particle formation (NPF events and the relative probability of observing particles originating from different spatial origins around three rural sites in eastern China were investigated using the NanoMap method, using particle number size distribution (PNSD data and air mass back trajectories. The length of the datasets used were 7, 1.5, and 3 years at rural sites Shangdianzi (SDZ in the North China Plain (NCP, Mt. Tai (TS in central eastern China, and Lin'an (LAN in the Yangtze River Delta region in eastern China, respectively. Regional NPF events were observed to occur with the horizontal extent larger than 500 km at SDZ and TS, favoured by the fast transport of northwesterly air masses. At LAN, however, the spatial footprint of NPF events was mostly observed around the site within 100–200 km. Difference in the horizontal spatial distribution of new particle source areas at different sites was connected to typical meteorological conditions at the sites. Consecutive large-scale regional NPF events were observed at SDZ and TS simultaneously and were associated with a high surface pressure system dominating over this area. Simultaneous NPF events at SDZ and LAN were seldom observed. At SDZ the polluted air masses arriving over the NCP were associated with higher particle growth rate (GR and new particle formation rate (J than air masses from Inner Mongolia (IM. At TS the same phenomenon was observed for J, but GR was somewhat lower in air masses arriving over the NCP compared to those arriving from IM. The capability of NanoMap to capture the NPF occurrence probability depends on the length of the dataset of PNSD measurement but also on topography around the measurement site and typical air mass advection speed during NPF events. Thus the long-term measurements of PNSD in the planetary boundary layer are necessary in the further study of spatial extent and the probability of NPF events. The spatial

  1. Shear wave anisotropy in the Eastern Himalaya, Burmese arc and adjoining regions

    Science.gov (United States)

    Mangalampally, R. K.; Saikia, D.; Singh, A.; Roy, S.; Panuganti, S. R.; Lyngdoh, A. C.

    2017-12-01

    This study presents new results of 231 shear wave splitting and 395 "Null" measurements at 58 broadband seismic stations installed in the hitherto less investigated eastern Himalaya, Burmese arc and adjoining regions. The analysis reveals complex patterns of anisotropy, with significant variations in delay times. The fast polarisation directions (FPD) at stations within the Himalaya, Burmese Arc and the foredeep are coherent, parallel to the strike of the orogens. Measurements within the eastern and central Arunachal Himalaya are predominantly "Null''. However, in the western and central parts, these are relatively small, centered at 0.7s. The FPDs follow the trends of major tectonic features like the Main Boundary Thrust and the Main Central Thrust in the central segment of Arunachal Himalaya. In the Burmese arc region, the delay times show a large variability (0.4-2.1s). The Assam foredeep exhibits splitting delays in the range 0.5 to 1.2 s, with the FPDs trending nearly EW to NE. The FPDs parallel to the strike of the mountain belts can be best explained in terms of a coherently deformed lithospheric mantle under the compressional effects ensuing from the collision between India and Asia. Null measurements in regions like the Siang window may be due to a complex anisotropic pattern due to Indian plate interaction with Eurasia and Burma plates, causing different layers of anisotropic fabric with completely different orientations. Another possibility is the coincidence of source polarisation direction with the fast axis, since most of the waveforms analysed are from a narrow back azimuthal range of 100-125°. E-W oriented FPDs may coincide with the backazimuth of the source, resulting in smaller delays. Null measurements in eastern Himalaya may reflect cancellation of anisotropy caused by APM related flow (NE) and compressional effects of the Himalaya (EW). In the Bengal Basin, the Nulls could be due to two different mechanisms, namely, frozen anisotropic fabric

  2. [Study on the factors impacting on early cochlear implantation between the eastern and western region of China].

    Science.gov (United States)

    Xiao, Hanqiong; Li, Wei; Ma, Ruixia; Gong, Zhengpeng; Shi, Haibo; Li, Huawei; Chen, Bing; Jiang, Ye; Dai, Chunfu

    2015-06-01

    To describe tne regional different factors which impact on early cochlear implantation in prelingual deaf children between eastern and western regions of China. The charts of 113 children who received the cochlear implantation after 24 months old were reviewed and analyzed. Forty-five of them came from the eastern region (Jiangsu, Zhejiang or Shanghai) while 68 of them came from the western region (Ningxia or Guizhou). Parental interviews were conducted to collect information regarding the factors that impact on early cochlear implantation. Result:Based on the univariate logistic regression analysis, the odds ratio (OR) value of universal newborn hearing screening (UNHS) was 5. 481, which indicated the correlation of UNHS with early cochlear implantation is significant. There was statistical difference between the 2 groups (P0. 05). The multivariate analysis indicated that the UNHS and financial burden are statistically different between the eastern and western regions (P=0. 00 and 0. 040 respectively). The UNHS and financial burden are statistically different between the eastern reinforced in the western region. In addition, the government and society should provide powerful policy and more financial support in the western region of China. The innovation of management system is also helpful to the early cochlear implantation.

  3. Vertical distribution and inventories of 137Cs in the Syrian soils of the eastern Mediterranean region

    International Nuclear Information System (INIS)

    Al-Masri, M.S.

    2006-01-01

    Vertical distribution and inventories of 137 Cs have been determined using radiocesium distributions in presumably undistributed soil profiles, collected from 36 sites distributed all over Syria (eastern Mediterranean region). Vertical distributions of 137 Cs in the collected profiles were found to be strongly correlated with soil type and five groups were identified. Based on these profiles, total 137 Cs inventory (bomb test and Chernobyl) varied between 320 Bq m -2 and 9647 Bq m -2 . Geographical mapping of 137 Cs inventories showed that the highest values were found in the coastal, middle and north-east regions of Syria indicating that Chernobyl atmospheric contribution to the total 137 Cs deposition in the region is predominant. In contrast, the lowest values were found in the south-east region (Syrian Badia), where a relatively uniform distribution was observed, which may only be attributed to the past global nuclear bomb test. The measured inventories were also compared with a mathematical model for estimating bomb derived 137 Cs reference inventories

  4. A regional response to global climate change: New England and eastern Canada

    International Nuclear Information System (INIS)

    Houtman, N.

    1994-01-01

    Resource managers, scientists, and policy makers from New England and eastern Canada assembled at a 1993 symposium to consider the regional implications of global climate change and to develop state and provincial adaptation strategies. A summary is presented of issues discussed at this meeting, information gaps identified, and recommendations for an appropriate regional response. The symposium began with a regional overview and a review of the climate system and possible environmental impacts of global warming. Policy implications were also discussed. Working groups considered issues related to energy use, ecosystems, fisheries, forestry and agriculture, recreation and tourism, and sea level rise. Given the remaining uncertainties about the timing and extent of global warming, especially on a regional scale, the symposium recommended adoption of a series of measures which are beneficial in their own right and in the face of present variations of climate and its extremes. The recommendations were characterized by three broad themes: diversification of the natural resources based economy; risks to human health, ecological communities, and economic infrastructure; and information development and sharing. Proposed strategies were grouped in four major categories: adaptation to future changes; trend assessment; education; and limitation of greenhouse gas emissions

  5. Interests and needs for participation in tourism among disabled from eastern regions of Poland.

    Science.gov (United States)

    Bergier, Barbara; Kubińska, Zofia; Bergier, Józef

    2013-01-01

    The scope of problems concerning the disabled still remains a constantly up-to-date social issue, which requires current scientific analysis. In concern for the disabled, the problem of physical activity through their participation in tourism occupies an important position. The studies concern the disabled from three regions: Lublin, Białystok and Rzeszów, where there occurs the highest intensity of the phenomenon of disability. The recognition of interests and needs manifested by the disabled from the eastern regions of Poland concerning the use of forms of tourism during leisure time. The method of a diagnostic survey and questionnaire technique were applied. A total number of 750 disabled were examined. The study showed that the majority of the disabled spend their free time devoted to tourist activity according to their needs. The main forms of participation in tourism are sightseeing tours and package holidays, and the respondents would like most to participate in rehabilitation camps and sightseeing tours. A considerable variation was observed in the participation in forms of tourism among the disabled from individual regions. The disabled who do not wish to participate in sports-recreation and tourist activities, and for whom their state of health is the main barrier, require special interest. A relatively large variation of tourism forms used by the disabled in individual regions indicate the need for an exchange of experiences between specialist facilities taking care of the disabled.

  6. Socio-economic vulnerability to climate change in the central mountainous region of eastern Mexico.

    Science.gov (United States)

    Esperón-Rodríguez, Manuel; Bonifacio-Bautista, Martín; Barradas, Víctor L

    2016-03-01

    Climate change effects are expected to be more severe for some segments of society than others. In Mexico, climate variability associated with climate change has important socio-economic and environmental impacts. From the central mountainous region of eastern Veracruz, Mexico, we analyzed data of total annual precipitation and mean annual temperature from 26 meteorological stations (1922-2008) and from General Circulation Models. We developed climate change scenarios based on the observed trends with projections to 2025, 2050, 2075, and 2100, finding considerable local climate changes with reductions in precipitation of over 700 mm and increases in temperature of ~9°C for the year 2100. Deforested areas located at windward were considered more vulnerable, representing potential risk for natural environments, local communities, and the main crops cultivated (sugarcane, coffee, and corn). Socio-economic vulnerability is exacerbated in areas where temperature increases and precipitation decreases.

  7. Heritage sites in the Eastern region of Cuba, new approaches for preservation

    Directory of Open Access Journals (Sweden)

    Luis Enrique Bello-Caballero

    2017-01-01

    Full Text Available The Eastern Region of Cuba holds five properties inscribed in the UNESCO World Heritage List, which evidence the cultural heritage richness. Therefore, several studies in the national context contribute to analyze the different process related to heritage sites management. However, the studies that embrace current deficiencies on heritage analysis and monitoring are yet insufficient. New studies should contribute to the control and the adoption of conservation actions, by means of the study, visualization and updating of information related to negative factors that influences the loss of cultural values, considering the preventive conservation approach. This paper aims at presenting the joint ongoing research between the Universidad de Oriente and the KU Leuven, within the frame of the VLIR IUC Project, which final goal is to design a method for the spatial analysis and monitoring of heritage sites through a GIS based tool implementation, with a preventive conservation approach.

  8. ANALYSIS OF LAND RESOURCES SUITABILITY BY FUNCTIONAL MODEL IN EASTERN CROATIA REGION

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    Vladimir Vukadinović

    2011-06-01

    Full Text Available A total of 17405 soil samples (2003rd-2009th years were analyzed in the eastern part of Croatia. The aim of this paper is to assess land suitability for crops i.e. to describe quantitatively land quality and indicate disadvantages of land using system in investigated area. The described mathematical model uses score functions for estimating indicators of soil suitability. Soil suitability assessment computer model for crops, supported by GIS, proved to be fast, efficient and enough reliable. Using GIS tool it is possible to visualize land suitability and present it in different cartographic bases such as maps whereas using geostatistical method – kriging enables to possible to provide regionalization of production area based on quantitative assessment of land suitability for crops.

  9. Migration in relation to possible tectonic and regional controls in eastern Australian volcanism

    International Nuclear Information System (INIS)

    Sutherland, F.L.

    1981-01-01

    The Wellman-McDougall model for southward migration of central volcano activity in eastern Australia is extended to the basaltic lava provinces. Latitude-age plots of volcanic episodes are related to trails initiated from regions of active volcanism at the commencement of northward drift of Australia (53 m.y. B.P.), from Southern Ocean spreading. These trails intersect at least 75%, and possibly up to 95%, of basaltic episodes and suggest a migratory control. The migration of central volcano felsic activity, however, consistently exceeds sea-floor spreading rates with a relative southward motion of 4-10 mm/yr. The trails give a mean migration direction of 24 PM 9 0 W of S before 29-30 m.y., but 8-12 0 W of S after 29 m.y. (orig./ME)

  10. Depression and Associated Factors among Adult Inpatients at Public Hospitals of Harari Regional State, Eastern Ethiopia

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    Haile Tilahun

    2018-01-01

    Full Text Available Introduction. Globally, depression is one of the three leading causes of disease and it will be the second leading cause of world disability by 2030. The prevalence of depression in Sub-Saharan Africa ranges from 15 to 30%. In Ethiopia, depression was found to be the seventh leading cause of disease burden and its prevalence has been increased in hospital compared to community setting because hospital environment itself is stressful. Yet, no study was done in Eastern Ethiopia, where substance use like Khat is very rampant. Objective. To assess depression and associated factors among adult inpatients at public hospitals of Harari Regional State, Eastern Ethiopia, from February 01 to 28, 2017. Methodology. Hospital based cross-sectional study design was employed on 492 admitted adult patients in Harari region hospitals. Consecutive sampling method was used to include study population. The data were collected by interviewee and analyzed by SPSS version 20.0. Bivariate and multivariate logistic regression analyses were employed. p value of 0.05 or less was considered to be statistically significant. Result. A total of 489 patients were interviewed with response rate of 99.4%. Having duration of 1-2 weeks in the hospital [AOR = 2.02, 95% CI: (1.28, 3.19], being diagnosed with chronic morbidity [AOR = 4.06, 95% CI: (2.23, 7.40], being users of psychoactive drugs [AOR = 2.24, 95% CI: (1.18, 4.24], and having been admitted to surgical ward [AOR = 0.50, 95% CI: (0.31, 0.81] were significantly associated with depression. Conclusion and Recommendation. Prevalence of depression among admitted inpatients was high. Therefore, increasing the awareness of benefits of early diagnosis of patients to prevent major form of depression and strengthening the clinical set-up and establishing good referral linkage with mental health institutions was considered to be cost-effective method to reduce its prevalence.

  11. Prevailing practices in the use of antibiotics by dairy farmers in Eastern Haryana region of India

    Science.gov (United States)

    Kumar, Vikash; Gupta, Jancy

    2018-01-01

    Aim: The aim of the study was to assess the antibiotic use in dairy animals and to trace its usage pattern among the small, medium, and large dairy farmers in Eastern Haryana region of India. Materials and Methods: Karnal and Kurukshetra districts from Eastern region of Haryana state were purposively selected, and four villages from each district were selected randomly. From each village, 21 farmers were selected using stratified random sampling by categorizing into small, medium, and large farmers constituting a total of 168 farmers as respondents. An antibiotic usage index (AUI) was developed to assess usage of antibiotics by dairy farmers. Results: Frequency of veterinary consultancy was high among large dairy farmers, and they mostly preferred veterinarians over para-veterinarians for treatment of dairy animals. Small farmers demanded low-cost antibiotics from veterinarians whereas large farmers rarely went for it. Antibiotics were used maximum for therapeutic purposes by all categories of farmers. Completion of treatment schedules and follow-up were strictly practiced by the majority of large farmers. AUI revealed that large farmers were more consistent on decision-making about prudent use of antibiotics. Routine use of antibiotics after parturition to prevent disease and sale of milk without adhering to withdrawal period was responsible for aggravating the antibiotic resistance. The extent of antibiotic use by small farmers depended on the severity of disease. The large farmers opted for the prophylactic use of antibiotics at the herd level. Conclusion: Antibiotic usage practices were judicious among large dairy farmers, moderately prudent by medium dairy farmers and faulty by small farmers. The frequency of veterinary consultancy promoted better veterinary-client relationship among large farmers. PMID:29657416

  12. Prevalence and risk factors associated with nutrition-related noncommunicable diseases in the Eastern Mediterranean region

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    Musaiger AO

    2012-02-01

    Full Text Available Abdulrahman O Musaiger1, Hazzaa M Al-Hazzaa21Nutrition and Health Studies Unit, Deanship of Scientific Research, University of Bahrain, Bahrain, and Arab Center for Nutrition, Bahrain; 2Exercise Physiology Laboratory, Department of Physical Education and Movement Science, College of Education, and Scientific Board, Obesity Research Chair, King Saud University, Riyadh, Saudi ArabiaAbstract: This paper reviews the current situation concerning nutrition-related noncommunicable diseases (N-NCDs and the risk factors associated with these diseases in the Eastern Mediterranean region (EMR. A systematic literature review of studies and reports published between January 1, 1990 and September 15, 2011 was conducted using the PubMed and Google Scholar databases. Cardiovascular disease, type 2 diabetes, metabolic syndrome, obesity, cancer, and osteoporosis have become the main causes of morbidity and mortality, especially with progressive aging of the population. The estimated mortality rate due to cardiovascular disease and diabetes ranged from 179.8 to 765.2 per 100,000 population, with the highest rates in poor countries. The prevalence of metabolic syndrome was very high, ranging from 19% to 45%. The prevalence of overweight and obesity (body mass index ≥25 kg/m2 has reached an alarming level in most countries of the region, ranging from 25% to 82%, with a higher prevalence among women. The estimated mortality rate for cancer ranged from 61.9 to 151 per 100,000 population. Osteoporosis has become a critical problem, particularly among women. Several risk factors may be contributing to the high prevalence of N-NCDs in EMR, including nutrition transition, low intake of fruit and vegetables, demographic transition, urbanization, physical inactivity, hypertension, tobacco smoking, stunting of growth of preschool children, and lack of nutrition and health awareness. Intervention programs to prevent and control N-NCDs are urgently needed, with special focus

  13. Geological and geomechanical properties of the carbonate rocks at the eastern Black Sea Region (NE Turkey)

    Science.gov (United States)

    Ersoy, Hakan; Yalçinalp, Bülent; Arslan, Mehmet; Babacan, Ali Erden; Çetiner, Gözde

    2016-11-01

    Turkey located in the Alpine-Himalayan Mountain Belt has 35% of the natural stone reserves of the world and has good quality marble, limestone, travertine and onyx reserves especially in the western regions of the country. The eastern Black Sea Region with a 1.4 million meters cubes reserve has a little role on the natural stone production in the country. For this reason, this paper deals with investigation on the potential of carbonate stone in the region and determination of the geological and geo-mechanical properties of these rocks in order to provide economic contribution to the national economy. While the study sites are selected among the all carbonate rock sites, the importance as well as the representative of the sites were carefully considered for the region. After representative samples were analyzed for major oxide and trace element compositions to find out petrochemical variations, the experimental program conducted on rock samples for determination of both physical and strength properties of the carbonate rocks. The results of the tests showed that there are significant variations in the geo-mechanical properties of the studied rock groups. The density values vary from 2.48 to 2.70 gr/cm3, water absorption by weight values range from 0.07 to 1.15% and the apparent porosity of the carbonate rocks are between 0.19 and 3.29%. However, the values of the UCS shows variation from 36 to 80 MPa. Tensile and bending strength values range from 3.2 to 7.5 MPa and 6.0-9.2 MPa respectively. Although the onyx samples have the lowest values of apparent porosity and water absorption by weight, these samples do not have the highest values of UCS values owing to occurrence of the micro-cracks. The UCS values of the rock samples were also found after cycling tests However, the limestone samples have less than 5% deterioration after freezing-thawing and wetting-drying tests, but travertine and onyx samples have more than 15% deterioration. Exception of the apparent

  14. A photoaffinity scan maps regions of the p85 SH2 domain involved in phosphoprotein binding.

    Science.gov (United States)

    Williams, K P; Shoelson, S E

    1993-03-15

    Src homology 2 (SH2) domains are modular phosphotyrosine binding pockets found within a wide variety of cytoplasmic signaling molecules. Here we develop a new approach to analyzing protein-protein interfaces termed photoaffinity scanning, and apply the method to map regions of the phosphatidylinositol 3-kinase p85 SH2 domain that participate in phospho-protein binding. Each residue except phosphotyrosine (pY) within a tightly binding, IRS-1-derived phosphopeptide (GNGDpYMPMSPKS) was substituted with the photoactive amino acid, benzoylphenylalanine (Bpa). Whereas most substitutions had little effect on binding affinity, Bpa substitution of either Met (+1 and +3 with respect to pY) reduced affinity 50-100-fold to confirm their importance in the pYMXM recognition motif. In three cases photolysis of SH2 domain/Bpa phosphopeptide complexes led to cross-linking of > 50% of the SH2 domain; cross-link positions were identified by microsequence, amino acid composition, and electrospray mass spectrometric analyses. Bpa-1 cross-links within alpha-helix I, whereas Bpa+1 and Bpa+4 cross-link the SH2 domain within the flexible loop C-terminal to alpha-helix II. Moreover, cross-linking at any position prevents SH2 domain cleavage at a trypsin-sensitive site within the flexible loop between beta-strands 1 and 2. Therefore, at least three distinct SH2 regions in addition to the beta-sheet participate in phosphoprotein binding; the loop cross-linked by phosphopeptide residues C-terminal to pY appears to confer specificity to the phosphoprotein/SH2 domain interaction.

  15. Distribution of inhalant allergies in pediatric patients presenting with allergic complaints in the Eastern Anatolia Region.

    Science.gov (United States)

    Kilic, Mehmet; Taskin, Erdal

    2016-08-01

    The objective of this study was to define the distribution of inhalant allergens in pediatric patients in whom sensitization was diagnosed with a skin prick test (SPT) who had presented with allergic complaints. In addition, the correlation between the inhalant allergens detected on the SPT and the patients' demographic features, diagnosis, and laboratory findings was defined. A total of 1415 children among the 4056 patients who presented at a clinic in the Eastern Anatolia region with allergic complaints and who had undergone an SPT were included in this study. On the SPT, sensitization to grass pollens was found in 60.1%, cereals pollens in 57.2%, and Dermatophagoides farinae in 21.8% of the patients. Furthermore, on the SPT, incidence of asthma development was 3.96 times higher (odds ratio 3.96, 95% CI: 1.77-6.83; P=0.001) in patients who were allergic to Dermatophagoides farinae. In our study, differences were found in the study region compared to data from around the world and other regions in Turkey in terms of the distribution of allergies and variations in allergens in patients diagnosed due to variations in climate and plants.

  16. Overweight and Obesity in Eastern Mediterranean Region: Prevalence and Possible Causes

    Directory of Open Access Journals (Sweden)

    Abdulrahman O. Musaiger

    2011-01-01

    Full Text Available The objective of this paper was to explore the prevalence of overweight and obesity among various age groups as well as discuss the possible factors that associated with obesity in the Eastern Mediterranean Region (EMR. A systematic review of published papers between 1990 and 2011 was carried out. Obesity reached an alarming level in all age groups of the EMR countries. The prevalence of overweight among preschool children(<5 years ranged from 1.9% to 21.9%, while the prevalence of overweight and obesity among school children ranged from 7% to 45%. Among adults the prevalence of overweight and obesity ranged from 25% to 81.9%. Possible factors determining obesity in this region include: nutrition transition, inactivity, urbanization, marital status, a shorter duration of breastfeeding, frequent snacking, skipping breakfast, a high intake of sugary beverages, an increase in the incidence of eating outside the home, long periods of time spent viewing television, massive marketing promotion of high fat foods, stunting, perceived body image, cultural elements and food subsidize policy. A national plan of action to overcome obesity is urgently needed to reduce the economic and health burden of obesity in this region.

  17. Relationship of spontaneous pneumothorax cases seen in Eastern Black Sea region with meteorological changes

    Science.gov (United States)

    Yamac, Mustafa Esat; Karapolat, Sami; Turkyilmaz, Atila; Seyis, Kubra Nur; Tekinbas, Celal

    2017-08-01

    The relationship of climate changes or weather conditions with the incidence of pneumothorax has been explored for many years. We aimed at revealing the effects of meteorological changes on the incidence of pneumothorax in the Eastern Black Sea region where spontaneous pneumothorax cases are seen relatively more frequently. The records of 195 subjects (179 males and 16 females) who had been monitored and treated due to spontaneous pneumothorax between January 2006 and December 2012 at our clinic were reviewed retrospectively, and their relationship was investigated with the meteorological data obtained by going through the database archive records of the 11th Regional Meteorology Directorate for the years between 2006 and 2012. Wind velocity was observed to be less in the days of having spontaneous pneumothorax than in the days of having no spontaneous pneumothorax, and the difference was found statistically significant ( P = 0.026). The people of our region whose active lifestyle is reflected in their working life, social life, and even in their folk dances usually take a rest in the days of slower wind speed. We think that this state of resting leads to an increase in the frequency of spontaneous pneumothorax.

  18. MAXENT MODELLING OF THE POTENTIAL DISTRIBUTION OF GANODERMA LUCIDUM IN NORTH-EASTERN REGION OF ROMANIA

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    Ovidiu COPOȚ

    2017-12-01

    Full Text Available Ganoderma lucidum is one of the most valued mushrooms in the World, because of its medicinal properties. In the context of North-Eastern Region’s development, any forest product could have a valuable contribution. Therefore, it is important to understand the mushroom’s ecology and generate a map of its optimal distribution. For this, we used one of the most performant species distribution models available – Maxent, field occurrences and climatic-topographic-biotic variables. After multi-collinearity testing and step-wise Maxent modelling, we came to an end with a 0.8 final model based on two predictors. Thus, in the region, the optimal habitat distribution is found in oak, beech, riparian or mixed forests bellow approximately 800 m altitude. The species can be found in almost all forests across lowland, colline and submontane regions according to tree host presence. The approach could be promising for other fungal species for the sustainable development of the region.

  19. Spectral nudging to eliminate the effects of domain position and geometry in regional climate model simulations

    Science.gov (United States)

    Miguez-Macho, Gonzalo; Stenchikov, Georgiy L.; Robock, Alan

    2004-07-01

    It is well known that regional climate simulations are sensitive to the size and position of the domain chosen for calculations. Here we study the physical mechanisms of this sensitivity. We conducted simulations with the Regional Atmospheric Modeling System (RAMS) for June 2000 over North America at 50 km horizontal resolution using a 7500 km × 5400 km grid and NCEP/NCAR reanalysis as boundary conditions. The position of the domain was displaced in several directions, always maintaining the U.S. in the interior, out of the buffer zone along the lateral boundaries. Circulation biases developed a large scale structure, organized by the Rocky Mountains, resulting from a systematic shifting of the synoptic wave trains that crossed the domain. The distortion of the large-scale circulation was produced by interaction of the modeled flow with the lateral boundaries of the nested domain and varied when the position of the grid was altered. This changed the large-scale environment among the different simulations and translated into diverse conditions for the development of the mesoscale processes that produce most of precipitation for the Great Plains in the summer season. As a consequence, precipitation results varied, sometimes greatly, among the experiments with the different grid positions. To eliminate the dependence of results on the position of the domain, we used spectral nudging of waves longer than 2500 km above the boundary layer. Moisture was not nudged at any level. This constrained the synoptic scales to follow reanalysis while allowing the model to develop the small-scale dynamics responsible for the rainfall. Nudging of the large scales successfully eliminated the variation of precipitation results when the grid was moved. We suggest that this technique is necessary for all downscaling studies with regional models with domain sizes of a few thousand kilometers and larger embedded in global models.

  20. Regional climate projections for the MENA-CORDEX domain: analysis of projected temperature and precipitation changes

    Science.gov (United States)

    Hänsler, Andreas; Weber, Torsten; Eggert, Bastian; Saeed, Fahad; Jacob, Daniela

    2014-05-01

    Within the CORDEX initiative a multi-model suite of regionalized climate change information will be made available for several regions of the world. The German Climate Service Center (CSC) is taking part in this initiative by applying the regional climate model REMO to downscale global climate projections of different coupled general circulation models (GCMs) for several CORDEX domains. Also for the MENA-CORDEX domain, a set of regional climate change projections has been established at the CSC by downscaling CMIP5 projections of the Max-Planck-Institute Earth System Model (MPI-ESM) for the scenarios RCP4.5 and RCP8.5 with the regional model REMO for the time period from 1950 to 2100 to a horizontal resolution of 0.44 degree. In this study we investigate projected changes in future climate conditions over the domain towards the end of the 21st century. Focus in the analysis is given to projected changes in the temperature and rainfall characteristics and their differences for the two scenarios will be highlighted.

  1. Summary of the Snake River plain Regional Aquifer-System Analysis in Idaho and eastern Oregon

    Science.gov (United States)

    Lindholm, G.F.

    1996-01-01

    Regional aquifers underlying the 15,600-square-mile Snake River Plain in southern Idaho and eastern Oregon was studied as part of the U.S. Geological Survey's Regional Aquifer-System Analysis program. The largest and most productive aquifers in the Snake River Plain are composed of Quaternary basalt of the Snake River Group, which underlies most of the 10,8000-square-mile eastern plain. Aquifer tests and simulation indicate that transmissivity of the upper 200 feet of the basalt aquifer in the eastern plain commonly ranges from about 100,000 to 1,000,000 feet squared per day. However, transmissivity of the total aquifer thickness may be as much as 10 million feet squared per day. Specific yield of the upper 200 feet of the aquifer ranges from about 0.01 to 0.20. Average horizontal hydraulic conductivity of the upper 200 feet of the basalt aquifer ranges from less than 100 to 9,000 feet per day. Values may be one to several orders of magnitude higher in parts in individual flows, such as flow tops. Vertical hydraulic conductivity is probably several orders of magnitude lower than horizontal hydraulic conductivity and is generally related to the number of joints. Pillow lava in ancestral Snake River channels has the highest hydraulic conductivity of all rock types. Hydraulic conductivity of the basalt decreases with depth because of secondary filling of voids with calcite and silica. An estimated 80 to 120 million acre-feet of water is believed to be stored in the upper 200 feet of the basalt aquifer in the eastern plain. The most productive aquifers in the 4,800-square-mile western plain are alluvial sand and gravel in the Boise River valley. Although aquifer tests indicate that transmissivity of alluvium in the Boise River valley ranges from 5,000 to 160,000 feet squared per day, simulation suggests that average transmissivity of the upper 500 feet is generally less than 20,000 feet squared per day. Vertically averaged horizontal hydraulic conductivity of the upper

  2. A closure study of aerosol optical properties at a regional background mountainous site in Eastern China

    Energy Technology Data Exchange (ETDEWEB)

    Yuan, Liang [Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters, Nanjing University of Information Science & Technology, Nanjing 210044 (China); Key Laboratory for Aerosol–Cloud–Precipitation of China Meteorological Administration, School of Atmospheric Physics, Nanjing University of Information Science and Technology, Nanjing 210044 (China); Yin, Yan, E-mail: yinyan@nuist.edu.cn [Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters, Nanjing University of Information Science & Technology, Nanjing 210044 (China); Key Laboratory for Aerosol–Cloud–Precipitation of China Meteorological Administration, School of Atmospheric Physics, Nanjing University of Information Science and Technology, Nanjing 210044 (China); Xiao, Hui [Key Laboratory for Aerosol–Cloud–Precipitation of China Meteorological Administration, School of Atmospheric Physics, Nanjing University of Information Science and Technology, Nanjing 210044 (China); Yu, Xingna [Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters, Nanjing University of Information Science & Technology, Nanjing 210044 (China); Key Laboratory for Aerosol–Cloud–Precipitation of China Meteorological Administration, School of Atmospheric Physics, Nanjing University of Information Science and Technology, Nanjing 210044 (China); Hao, Jian; Chen, Kui [Key Laboratory for Aerosol–Cloud–Precipitation of China Meteorological Administration, School of Atmospheric Physics, Nanjing University of Information Science and Technology, Nanjing 210044 (China); and others

    2016-04-15

    There is a large uncertainty in evaluating the radiative forcing from aerosol–radiation and aerosol–cloud interactions due to the limited knowledge on aerosol properties. In-situ measurements of aerosol physical and chemical properties were carried out in 2012 at Mt. Huang (the Yellow Mountain), a continental background mountainous site in eastern China. An aerosol optical closure study was performed to verify the model outputs by using the measured aerosol optical properties, in which a spherical Mie model with assumptions of external and core–shell mixtures on the basis of a two-component optical aerosol model and high size-segregated element carbon (EC) ratio was applied. Although the spherical Mie model would underestimate the real scattering with increasing particle diameters, excellent agreement between the calculated and measured values was achieved with correlation coefficients above 0.98. Sensitivity experiments showed that the EC ratio had a negligible effect on the calculated scattering coefficient, but largely influenced the calculated absorption coefficient. The high size-segregated EC ratio averaged over the study period in the closure was enough to reconstruct the aerosol absorption coefficient in the Mie model, indicating EC size resolution was more important than time resolution in retrieving the absorption coefficient in the model. The uncertainties of calculated scattering and absorption coefficients due to the uncertainties of measurements and model assumptions yielded by a Monte Carlo simulation were ± 6% and ± 14% for external mixture and ± 9% and ± 31% for core–shell mixture, respectively. This study provided an insight into the inherent relationship between aerosol optical properties and physicochemical characteristics in eastern China, which could supplement the database of aerosol optical properties for background sites in eastern China and provide a method for regions with similar climate. - Highlights: • A spherical Mie

  3. Farmer–African wild dog (Lycaon pictus relations in the eastern Kalahari region of Botswana

    Directory of Open Access Journals (Sweden)

    Valli-Laurente Fraser-Celin

    2017-05-01

    Full Text Available African wild dogs (Lycaon pictus are the most endangered large carnivores in southern Africa. Direct and indirect persecution by farmers causes significant conservation challenges. Farmer– wild dog conflict in Botswana commonly occurs as a result of cattle and stocked game depredation by wild dogs, affecting farmer livelihood and causing economic and emotional distress. Although wild dogs predate livestock at lower levels than other carnivores, they continue to be killed both indiscriminately and in retaliation for incidents of depredation. Investigating farmer–wild dog conflict is a necessary step towards establishing appropriate conflict mitigation strategies. Eighty livestock and game farmers were interviewed in order to examine farmers’ value of, perceptions of and experiences with wild dogs as well as their insights on wild dog impacts and conservation in the eastern Kalahari region of Botswana. Interviews were semi-structured and used open-ended questions to capture complexities surrounding farmer–wild dog relations. This research contributes baseline data on wild dogs in understudied tribal land and commercial livestock and game farms in eastern Kalahari. It confirms the presence of wild dogs, livestock and stocked game depredation by wild dogs and negative perspectives amongst farmers towards wild dogs and their conservation. Mean losses were 0.85 livestock per subsistence farmer, 1.25 livestock per commercial livestock farmer, while game farmers lost 95.88 game animals per farmer during January 2012 through June 2013. Proportionally, more subsistence farmers than commercial livestock farmers and game farmers held negative perspectives of wild dogs (χ ² = 9.63, df = 2, p < 0.05. Farmer type, education level, socioeconomic status and land tenure, as well as positive wild dog characteristics should be considered when planning and operationalising conflict mitigation strategies. As such, conservation approaches should focus on

  4. A closure study of aerosol optical properties at a regional background mountainous site in Eastern China

    International Nuclear Information System (INIS)

    Yuan, Liang; Yin, Yan; Xiao, Hui; Yu, Xingna; Hao, Jian; Chen, Kui

    2016-01-01

    There is a large uncertainty in evaluating the radiative forcing from aerosol–radiation and aerosol–cloud interactions due to the limited knowledge on aerosol properties. In-situ measurements of aerosol physical and chemical properties were carried out in 2012 at Mt. Huang (the Yellow Mountain), a continental background mountainous site in eastern China. An aerosol optical closure study was performed to verify the model outputs by using the measured aerosol optical properties, in which a spherical Mie model with assumptions of external and core–shell mixtures on the basis of a two-component optical aerosol model and high size-segregated element carbon (EC) ratio was applied. Although the spherical Mie model would underestimate the real scattering with increasing particle diameters, excellent agreement between the calculated and measured values was achieved with correlation coefficients above 0.98. Sensitivity experiments showed that the EC ratio had a negligible effect on the calculated scattering coefficient, but largely influenced the calculated absorption coefficient. The high size-segregated EC ratio averaged over the study period in the closure was enough to reconstruct the aerosol absorption coefficient in the Mie model, indicating EC size resolution was more important than time resolution in retrieving the absorption coefficient in the model. The uncertainties of calculated scattering and absorption coefficients due to the uncertainties of measurements and model assumptions yielded by a Monte Carlo simulation were ± 6% and ± 14% for external mixture and ± 9% and ± 31% for core–shell mixture, respectively. This study provided an insight into the inherent relationship between aerosol optical properties and physicochemical characteristics in eastern China, which could supplement the database of aerosol optical properties for background sites in eastern China and provide a method for regions with similar climate. - Highlights: • A spherical Mie

  5. Regional hydrology of the Dolores River Basin, eastern Paradox Basin, Colorado and Utah

    International Nuclear Information System (INIS)

    Weir, J.E. Jr.; Maxfield, E.B.; Zimmerman, E.A.

    1983-01-01

    The Dolores River Basin, is in the eastern part of the Paradox Basin and includes the eastern slope of the La Sal Mountains, the western slopes of the Rico and La Plata Mountains, and the southwest flank of the Uncompahgre Plateau. The climate of this area is more humid than most of the surrounding Colorado Plateau region. Precipitation ranges from slightly 200 mm/yr to 1000 mm/yr; the estimated volume of water falling on the area is 4000 x 10 6 cm 3 /yr. Of this total, about 600 x 10 6 cm 3 /yr is runoff; 190 x 10 6 cm 3 /yr recharges the upper ground-water system; and an estimated 55 x 10 6 cm 3 returns to the atmosphere via evapotranspiration from stream valleys. The remainder evaporates. Principal hydrogeologic units are permeable sandstone and limestone and nearly impermeable salt (halitic) deposits. Structurally, the area is dominated by northwest-trending salt anticlines and contiguous faults paralleled by synclinal structures. The Uncompahgre Plateau lies along the north and northeast sides of the area. The instrusive masses that form the La Sal Mountains are laccoliths with bysmaliths and other complex intrusive forms comprising, in gross form, moderately faulted omal structures. Intrusive rocks underlie the La Plata and Rico Mountains along the southeastern edge of the area. These geologic structures significantly modify ground-water flow patterns in the upper ground-water system, but have no conspicuous effect on the flow regime in the lower ground-water system. The water in the upper ground-water system generally is fresh except where it is affected by evaporite dissolution from salt anticlines. The water of the lower ground-water system is slightly saline to briny. Water quality of the Dolores River is slightly saline to fresh, based on dissolved chemical constituents; some of the smaller tributaries of the river have saline water

  6. Screening procedure to evaluate effects of air pollution on Eastern Region wildernesses cited as Class I air quality areas.

    Science.gov (United States)

    Mary Beth Adams; Dale S. Nichols; Anthony C. Federer; Keith F. Jensen; Harry Parrott

    1991-01-01

    The USDA Forest Service's Eastern Region manages eight wilderness areas that have been designated as Class I air quality areas by the Federal Clean Air Act. As part of this legislation, Federal land managers are required to consult with air pollution regulators on the potential impacts of proposed air pollution emissions--including phytotoxic gases and acidic...

  7. From chemicals to cold plasma: Non-thermal food processing technologies research at the USDA's Eastern Regional Research Center

    Science.gov (United States)

    Foodborne pathogens cause millions of illnesses every year. At the US Department of Agriculture’s Eastern Regional Research Center, scientists and engineers have focused on developing new ways to improve food safety and shelf life while retaining quality and nutritional value. A variety of technolog...

  8. Agreement for the Establishment in Cairo of a Middle Eastern Regional Radioisotope Centre for the Arab Countries

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1962-10-18

    On 14 September 1962 the Board of Governors approved an Agreement for the establishment in Cairo of a Middle Eastern regional radioisotope centre for the Arab countries. The text of this Agreement is reproduced in this document for the information of all Members.

  9. Agreement for the Establishment in Cairo of a Middle Eastern Regional Radioisotope Centre for the Arab Countries

    International Nuclear Information System (INIS)

    1962-01-01

    On 14 September 1962 the Board of Governors approved an Agreement for the establishment in Cairo of a Middle Eastern regional radioisotope centre for the Arab countries. The text of this Agreement is reproduced in this document for the information of all Members

  10. Surface Wave Analysis of Regional Earthquakes in the Eastern Rift System (Africa)

    Science.gov (United States)

    Oliva, S. J. C.; Guidarelli, M.; Ebinger, C. J.; Roecker, S. W.; Tiberi, C.

    2015-12-01

    The Northern Tanzania Divergence (NTD), the youngest part of the East African Rift System, presents the opportunity to obtain insights about the birth and early stages of rifting before it progresses to mature rifting and seafloor spreading. This region is particularly interesting because the Eastern rift splits into three arms in this area and develops in a region of thick and cold lithosphere, amid the Archaean Tanzanian craton and the Proterozoic orogenic belt (the Masai block). We analyzed about two thousand seismic events recorded by the 39 broadband stations of the CRAFTI network during its two-year deployment in the NTD area in 2013 to 2014. We present the results of surface wave tomographic inversion obtained from fundamental-mode Rayleigh waves for short periods (between 4 to 14 seconds). Group velocity dispersion curves obtained via multiple filter analysis are path-averaged and inverted to produce 0.1º x 0.1º nodal grid tomographic maps for discrete periods using a 2D generalization of the Backus and Gilbert method. To quantify our results in terms of S-wave velocity structure the average group velocity dispersion curves are then inverted, using a linearized least-squares inversion scheme, in order to obtain the shear wave velocity structure for the upper 20 km of the crust. Low velocity anomalies are observed in the region 50 km south of Lake Natron, as well as in the area of the Ngorongoro crater. The implications of our results for the local tectonics and the development of the rifting system will be discussed in light of the growing geophysical database from this region.

  11. Program of Regional Collaboration between Eastern Part of Russia and Northeast China: Present and Future

    Directory of Open Access Journals (Sweden)

    Dmitriy Aleksandrovich Izotov

    2014-06-01

    Full Text Available The author uses Russian and Chinese sources of information to analyze the current status and evaluate realization prospects of investment projects within the Cooperation Program between eastern regions of Russia and northeast China. State budget financed construction of transport and border infrastructure is being implemented as planned both in Russia and China. Sectoral distribution of key Program projects is found to be unbalanced: Russian regions specialize in mining and primary processing of natural resources while Chinese ones - in products with high share of added value. The study reveals that among 104 scheduled key Russian projects (at the cost of 47,9 billion USD only 24 projects are under implementation (11,77 billion USD, 8 of which are carried out with the help of Chinese investments (1,77 billion USD. Joint ventures are connected with mining operations, primary processing of wood, construction of houses, manufacturing of building materials, assembly production and trade. Among 111 scheduled Program Chinese projects (at the cost of 9,87 billion USD only 42 projects are under implementation (6,1 billion USD; they are associated with engineering products. There is only one Russian-Chinese joint venture on the territory of China (at the cost of 0,63 billion USD. The author suggests that in the near future 20 additional Program projects can be implemented in Russia (at the cost of more than 20 billion USD and 6 projects (about 0,5 billion USD - in China

  12. Complex emergencies in the Eastern Mediterranean Region: Impact on tuberculosis control.

    Science.gov (United States)

    Seita, Akihiro

    2016-12-01

    The Eastern Mediterranean Region (EMR) has witnessed the largest refugee crisis in history. Overall, 70% of the global refugee populations are from Palestine, Syria, Afghanistan, or Somalia. We reviewed the possible impact of such crisis on the tuberculosis situation in EMR. We used the available data and information from the World Health Organization and other international and national institutions. Overall, 15 out of 22 countries in the EMR are either engulfed in complex emergencies (10 countries) or suffering from their neighbors' complex emergencies (7 countries), whereas two countries suffer from both. Eighty-five percent of the total population (636 million) in the region lives in these 15 countries. For tuberculosis, these 15 countries account for a significant burden in EMR: 94% of the estimated total incidence of 740,000 cases a year and 95% of the estimated total mortality of 91,000 a year. These countries have yet to show the significant negative impact on tuberculosis epidemiology as such changes take considerable time to manifest. Still, there are reports on health systems impact: access to health facilities, destruction of health facilities, health staff casualties, and shortage of medicines. Complex emergencies pose a significant negative impact on tuberculosis in the EMR. This issue should be raised in the global health and political arena. This is a time bomb for tuberculosis. Copyright © 2016.

  13. The rheological structure of the lithosphere in the Eastern Marmara region, Turkey

    Science.gov (United States)

    Oruç, Bülent; Sönmez, Tuba

    2017-05-01

    The aim of this work is to propose the geometries of the crustal-lithospheric mantle boundary (Moho) and lithosphere-asthenosphere boundary (LAB) and the 1D thermal structure of the lithosphere, in order to establish a rheological model of the Eastern Marmara region. The average depths of Moho and LAB are respectively 35 km and 51 km from radially averaged amplitude spectra of EGM08 Bouguer anomalies. The geometries of Moho and LAB interfaces are estimated from the Parker-Oldenburg gravity inversion algorithm. Our results show the Moho depth varies from 31 km at the northern part of North Anatolian Fault Zone (NAFZ) to 39 km below the mountain belt in the southern part of the NAFZ. The depth to the LAB beneath the same parts of the region ranges from 45 km to 55 km. Having lithospheric strength and thermal boundary layer structure, we analyzed the conditions of development of lithosphere thinning. A two-dimensional strength profile has been estimated for rheology model of the study area. Thus we suggest that the rheological structure consists of a strong upper crust, a weak lower crust, and a partly molten upper lithospheric mantle.

  14. Changing trend in congenital abdominal wall defects in Eastern region of Ireland.

    LENUS (Irish Health Repository)

    McDonnell, R

    2002-09-01

    In the past six years, there have been reports from abroad of an unexplained rise in the birth prevalence rate of the congenital abdominal wall defect gastroschisis, while rates for the macroscopically similar anomaly omphalocoele have remained stable. The Dublin EUROCAT Registry of congenital anomalies monitors trends in the birth prevalence of birth defects in the eastern region of Ireland. We analysed births of children with omphalocoele and gastroschisis born in the period 1981-2000, with comparisons of a number of demographic and obstetric variables. During the 20 year period the birth prevalence rate for omphalocoele remained stable at 2.5\\/10,000 births, whereas the rate for gastroschisis increased significantly during the 1990s from 1.0\\/10,000 in 1991 to 4.9\\/10,000 in 2000. Most of the increase occurred among mothers under 25 years of age. Omphalocoele was associated with a relatively high proportion of other major congenital anomalies. This study showed that there has been an unexpected rise in the birth prevalence of gastroschisis in the region, similar to that experienced in other countries in the same time period and likely to have common aetiological features.

  15. Sensitivity of simulated regional Arctic climate to the choice of coupled model domain

    Directory of Open Access Journals (Sweden)

    Dmitry V. Sein

    2014-07-01

    Full Text Available The climate over the Arctic has undergone changes in recent decades. In order to evaluate the coupled response of the Arctic system to external and internal forcing, our study focuses on the estimation of regional climate variability and its dependence on large-scale atmospheric and regional ocean circulations. A global ocean–sea ice model with regionally high horizontal resolution is coupled to an atmospheric regional model and global terrestrial hydrology model. This way of coupling divides the global ocean model setup into two different domains: one coupled, where the ocean and the atmosphere are interacting, and one uncoupled, where the ocean model is driven by prescribed atmospheric forcing and runs in a so-called stand-alone mode. Therefore, selecting a specific area for the regional atmosphere implies that the ocean–atmosphere system can develop ‘freely’ in that area, whereas for the rest of the global ocean, the circulation is driven by prescribed atmospheric forcing without any feedbacks. Five different coupled setups are chosen for ensemble simulations. The choice of the coupled domains was done to estimate the influences of the Subtropical Atlantic, Eurasian and North Pacific regions on northern North Atlantic and Arctic climate. Our simulations show that the regional coupled ocean–atmosphere model is sensitive to the choice of the modelled area. The different model configurations reproduce differently both the mean climate and its variability. Only two out of five model setups were able to reproduce the Arctic climate as observed under recent climate conditions (ERA-40 Reanalysis. Evidence is found that the main source of uncertainty for Arctic climate variability and its predictability is the North Pacific. The prescription of North Pacific conditions in the regional model leads to significant correlation with observations, even if the whole North Atlantic is within the coupled model domain. However, the inclusion of the

  16. Predicting binding within disordered protein regions to structurally characterised peptide-binding domains.

    Directory of Open Access Journals (Sweden)

    Waqasuddin Khan

    Full Text Available Disordered regions of proteins often bind to structured domains, mediating interactions within and between proteins. However, it is difficult to identify a priori the short disordered regions involved in binding. We set out to determine if docking such peptide regions to peptide binding domains would assist in these predictions.We assembled a redundancy reduced dataset of SLiM (Short Linear Motif containing proteins from the ELM database. We selected 84 sequences which had an associated PDB structures showing the SLiM bound to a protein receptor, where the SLiM was found within a 50 residue region of the protein sequence which was predicted to be disordered. First, we investigated the Vina docking scores of overlapping tripeptides from the 50 residue SLiM containing disordered regions of the protein sequence to the corresponding PDB domain. We found only weak discrimination of docking scores between peptides involved in binding and adjacent non-binding peptides in this context (AUC 0.58.Next, we trained a bidirectional recurrent neural network (BRNN using as input the protein sequence, predicted secondary structure, Vina docking score and predicted disorder score. The results were very promising (AUC 0.72 showing that multiple sources of information can be combined to produce results which are clearly superior to any single source.We conclude that the Vina docking score alone has only modest power to define the location of a peptide within a larger protein region known to contain it. However, combining this information with other knowledge (using machine learning methods clearly improves the identification of peptide binding regions within a protein sequence. This approach combining docking with machine learning is primarily a predictor of binding to peptide-binding sites, and is not intended as a predictor of specificity of binding to particular receptors.

  17. The PLAC1-homology region of the ZP domain is sufficient for protein polymerisation

    Directory of Open Access Journals (Sweden)

    Litscher Eveline S

    2006-04-01

    Full Text Available Abstract Background Hundreds of extracellular proteins polymerise into filaments and matrices by using zona pellucida (ZP domains. ZP domain proteins perform highly diverse functions, ranging from structural to receptorial, and mutations in their genes are responsible for a number of severe human diseases. Recently, PLAC1, Oosp1-3, Papillote and CG16798 proteins were identified that share sequence homology with the N-terminal half of the ZP domain (ZP-N, but not with its C-terminal half (ZP-C. The functional significance of this partial conservation is unknown. Results By exploiting a highly engineered bacterial strain, we expressed in soluble form the PLAC1-homology region of mammalian sperm receptor ZP3 as a fusion to maltose binding protein. Mass spectrometry showed that the 4 conserved Cys residues within the ZP-N moiety of the fusion protein adopt the same disulfide bond connectivity as in full-length native ZP3, indicating that it is correctly folded, and electron microscopy and biochemical analyses revealed that it assembles into filaments. Conclusion These findings provide a function for PLAC1-like proteins and, by showing that ZP-N is a biologically active folding unit, prompt a re-evaluation of the architecture of the ZP domain and its polymers. Furthermore, they suggest that ZP-C might play a regulatory role in the assembly of ZP domain protein complexes.

  18. Discovery of Miocene adakitic dacite from the Eastern Pontides Belt (NE Turkey) and a revised geodynamic model for the late Cenozoic evolution of the Eastern Mediterranean region

    Science.gov (United States)

    Eyuboglu, Yener; Santosh, M.; Yi, Keewook; Bektaş, Osman; Kwon, Sanghoon

    2012-08-01

    The Cenozoic magmatic record within the ca. 500 km long eastern Pontides orogen, located within the Alpine metallogenic belt, is critical to evaluate the tectonic history and geodynamic evolution of the eastern Mediterranean region. In this paper we report for the first time late Miocene adakitic rocks from the southeastern part of the eastern Pontides belt and present results from geochemical and Sr-Nd isotopic studies as well as zircon U-Pb geochronology. The Tavdagi dacite that we investigate in this study is exposed as round or ellipsoidal shaped bodies, sills, and dikes in the southeastern part of the belt. Zircons in the dacite show euhedral crystal morphology with oscillatory zoning and high Th/U values (up to 1.69) typical of magmatic origin. Zircon LA-ICPMS analysis yielded a weighted mean 206Pb/238U age of 7.86 ± 0.15 Ma. SHRIMP analyses of zircons with typical magmatic zoning from another sample yielded a weighted mean 206Pb/238U age of 8.79 ± 0.19 Ma. Both ages are identical and constrain the timing of dacitic magmatism as late Miocene. The Miocene Tavdagi dacite shows adakitic affinity with high SiO2 (68.95-71.41 wt.%), Al2O3 (14.88-16.02 wt.%), Na2O (3.27-4.12 wt.%), Sr (331.4-462.1 ppm), Sr/Y (85-103.7), LaN/YbN (34.3-50.9) and low Y (3.2-5 ppm) values. Their initial 143Nd/144Nd (0.512723-0.512736) and 87Sr/86Sr (0.70484-0.70494) ratios are, respectively, lower and higher than those of normal oceanic crust. The geological, geochemical and isotopic data suggest that the adakitic magmatism was generated by partial melting of the mafic lower crust in the southeastern part of the eastern Pontide belt during the late Miocene. Based on the results presented in this study and a synthesis of the geological and tectonic information on the region, we propose that the entire northern edge of the eastern Pontides-Lesser Caucasus-Elbruz magmatic arc was an active continental margin during the Cenozoic. We identify a migration of the Cenozoic magmatism towards

  19. Sequential assignment of proline-rich regions in proteins: Application to modular binding domain complexes

    International Nuclear Information System (INIS)

    Kanelis, Voula; Donaldson, Logan; Muhandiram, D.R.; Rotin, Daniela; Forman-Kay, Julie D.; Kay, Lewis E.

    2000-01-01

    Many protein-protein interactions involve amino acid sequences containing proline-rich motifs and even poly-proline stretches. The lack of amide protons in such regions complicates assignment, since 1 HN-based triple-resonance assignment strategies cannot be employed. Two such systems that we are currently studying include an SH2 domain from the protein Crk with a region containing 9 prolines in a 14 amino acid sequence, as well as a WW domain that interacts with a proline-rich target. A modified version of the HACAN pulse scheme, originally described by Bax and co-workers [Wang et al. (1995) J. Biomol. NMR, 5, 376-382], and an experiment which correlates the intra-residue 1 H α , 13 C α / 13 C β chemical shifts with the 15 N shift of the subsequent residue are presented and applied to the two systems listed above, allowing sequential assignment of the molecules

  20. Sarcocystis neurona: molecular characterization of enolase domain I region and a comparison to other protozoa.

    Science.gov (United States)

    Bolten, K E; Marsh, A E; Reed, S M; Dubey, J P; Toribio, R E; Saville, W J A

    2008-09-01

    Sarcocystis neurona causes protozoal myeloencephalitis and has the ability to infect a wide host range in contrast to other Sarcocystis species. In the current study, five S. neurona isolates from a variety of sources, three Sarcocystis falcatula, one Sarcocystis dasypi/S. neurona-like isolate, and one Besnoitia darlingi isolate were used to compare the enolase 2 gene segment containing the domain I region to previously sequenced enolase genes from Neospora caninum, Neospora hughesi, Toxoplasma gondii, Plasmodium falciparum, and Trypanosoma cruzi; enolase 2 segment containing domain I region is highly conserved amongst these parasites of veterinary and medical importance. Immunohistochemistry results indicates reactivity of T. gondii enolase 1 and 2 antibodies to S. neurona merozoites and metrocytes, but no reactivity of anti-enolase 1 to the S. neurona bradyzoite stage despite reactivity to T. gondii bradyzoites, suggesting expression differences between organisms.

  1. Influence of Indian summer monsoon variability on the surface waves in the coastal regions of eastern Arabian Sea

    Digital Repository Service at National Institute of Oceanography (India)

    SanilKumar, V.; Jesbin, G.

    –885, 2016 www.ann-geophys.net/34/871/2016/ doi:10.5194/angeo-34-871-2016 © Author(s) 2016. CC Attribution 3.0 License. Influence of Indian summer monsoon variability on the surface waves in the coastal regions of eastern Arabian Sea V. Sanil Kumar and Jesbin... of the period. The annual average value is ∼ 1.5 m (Anoop et al., 2015). During the non-monsoon period, the land and sea breeze has a signif- icant influence on the wave climate of eastern AS (Glejin Ann. Geophys., 34, 871–885, 2016 www.ann-geophys.net/34...

  2. Aspects of sismo-tectonic stability in the South-Eastern region of Brazil of interest to geology of engineering

    International Nuclear Information System (INIS)

    Mioto, J.A.; Hasui, Y.

    1982-01-01

    The occurence of earthquakes in Brazil, mainly in the South-eastern region, and its relationship with the geologic features has been discussed by many Authors since the beginning of this Century. It is difficult to define intraplate seismicity and to understand the actual epirogenic displacent, but the definition of the regional stability is important for enginnering purposes and have been considered through seismologic, morphotectonic and geologic criteria. (Author) [pt

  3. Post-Ocular Trauma Corneal Staphyloma in a Child Living in an Underdeveloped Region of Eastern Indonesia

    OpenAIRE

    Ratna Sitompul; Gladys Kusumowidagdo; Eiko B. Matiur; Julie D. Barliana; Rita S. Sitorus; Saleha Sungkar

    2018-01-01

    Ocular trauma occurring in children often leads to visual impairment or blindness when it is not properly managed. This often occurs in underdeveloped regions with difficult access to professional care at local health facilities. We report a case of post-trauma corneal staphyloma in an underdeveloped region of eastern Indonesia to illustrate the importance of proper management of ocular trauma in areas lacking such expertise and where patients have difficulty accessing even basic health care....

  4. Land use impact on soil quality in eastern Himalayan region of India.

    Science.gov (United States)

    Singh, A K; Bordoloi, L J; Kumar, Manoj; Hazarika, S; Parmar, Brajendra

    2014-04-01

    Quantitative assessment of soil quality is required to determine the sustainability of land uses in terms of environmental quality and plant productivity. Our objective was to identify the most appropriate soil quality indicators and to evaluate the impact of six most prevalent land use types (natural forestland, cultivated lowland, cultivated upland terrace, shifting cultivation, plantation land, and grassland) on soil quality in eastern Himalayan region of India. We collected 120 soil samples (20 cm depth) and analyzed them for 29 physical, chemical, and biological soil attributes. For selection of soil quality indicators, principal component analysis (PCA) was performed on the measured attributes, which provided four principal components (PC) with eigenvalues >1 and explaining at least 5% of the variance in dataset. The four PCs together explained 92.6% of the total variance. Based on rotated factor loadings of soil attributes, selected indicators were: soil organic carbon (SOC) from PC-1, exchangeable Al from PC-2, silt content from PC-3, and available P and Mn from PC-4. Indicators were transformed into scores (linear scoring method) and soil quality index (SQI) was determined, on a scale of 0-1, using the weighting factors obtained from PCA. SQI rating was the highest for the least-disturbed sites, i.e., natural forestland (0.93) and grassland (0.87), and the lowest for the most intensively cultivated site, i.e., cultivated upland terrace (0.44). Ratings for the other land uses were shifting cultivation (0.60) > cultivated low land (0.57) > plantation land (0.54). Overall contribution (in percent) of the indicators in determination of SQI was in the order: SOC (58%) > exch. Al (17.1%) > available P (8.9%) > available Mn (8.2%) > silt content (7.8%). Results of this study suggest SOC and exch. Al as the two most powerful indicators of soil quality in study area. Thus, organic C and soil acidity management holds the key to improve soil

  5. The status of childhood blindness and functional low vision in the Eastern Mediterranean region in 2012.

    Science.gov (United States)

    Khandekar, Rajiv; Kishore, H; Mansu, Rabiu M; Awan, Haroon

    2014-01-01

    Childhood blindness and visual impairment (CBVI) are major disabilities that compromise the normal development of children. Health resources and practices to prevent CBVI are suboptimal in most countries in the Eastern Mediterranean Region (EMR). We reviewed the magnitude and the etiologies of childhood visual disabilities based on the estimates using socioeconomic proxy indicators such as gross domestic product (GDP) per capita and blindness (defined as  Best corrected visual acuity(BCVA)) less than 3/60 in the better eye or a visual field of 10° surrounding central fixation) and functional low vision (FLV) (visual impairment for which no treatment or refractive correction can improve the vision up to >6/18 in a better eye) in children blindness and FLV rates to high, middle- and low-income countries from the global literature to the population of children blindness (rate 1.2/1,000) in the region. In addition, there could be approximately 417,725 children with FLV (rate of 2.1/1,000) in the region. The causes of visual disability in the three groups are also discussed based on the available data. As our estimates are based on hospital and blind school studies in the past, they could have serious limitations for projecting the present magnitude and causes of visual disabilities in children of EMR. An effective approach to eye health care and screening for children within primary health care and with the available resources are discussed. The objectives, strategies, and operating procedures for child eye-care are presented. Variables impacting proper screening are discussed. To reach the targets, we recommend urgent implementation of new approaches to low vision and rehabilitation of children.

  6. The Moroccan eastern region, a green energy complex for sustainable development and advanced decentralization

    Science.gov (United States)

    Belhaj, Siham; Bahi, Lahcen; Akhssas, Ahmed; Jalal El hamidi, Mohamed

    2017-04-01

    The Moroccan eastern region is characterized by: A total population 2,314,346 inhabitants (in 2014) (6.84% of the population of Morocco) by a density 24 inhabitants per km2. The population structure is as follows: 30% under 15 years of age, 50% of the population is under 25 years of age, 61% of working age (15-60 years), 9% in the third age group (over than 60 years). An urbanization rate of 58.5% with an economic profile GDP: 44.2 MMDH / year. GDP growth rate: 10.8% .The Oriental contribution to the formation of the national GDP is 4.9%, in the region we have the predominance of two activities: Tertiary (51.4%) and Secondary activities (22.3%). Concerning the clean resources of energy we can mention: - Abundant solar resources because the average radiation on a surface inclined at 30 ° is 2,082 kWh / (m2 / year); An important potential of the wind distributed in: offshore at sea along the Mediterranean facade (197 km of coast) and the onshore wind along the ridges of the mountains; Large biomass potential for biogas production; A precise zoning of the territories destined to shelter installations of production of the electricity of solar. We will in this work express the importance of this diversity of the clean energy resources -projects- cited in the region of the east to develop: Production of solar photovoltaic energy; Production of solar and thermal energy; Hydropower production; the valorization of biomass (biogas, biofuel, etc.); Production of geothermal energy; Keywords: Oujda, Sustainable Development, Energy

  7. Mississippian subadults from the Middle Cumberland and Eastern regions of Tennessee: Biological indicators of population interaction.

    Science.gov (United States)

    Scopa Kelso, Rebecca

    2018-02-23

    Human subadult skeletal remains can provide a unique perspective into biosocial aspects of Mississippian period population interactions within and between the Middle Cumberland (MCR) and Eastern Tennessee Regions (ETR). The majority of previous studies have concentrated on adult skeletal remains, leaving out a large and extremely important population segment. Skeletal indicators of disease, growth, body proportions, and metabolic stress were collected from subadult remains from five archaeological sites over several temporal periods. Crucial to overcoming limitations associated with the osteological paradox, the biological results were placed into an archaeological context based on prior studies as well as paleoclimatological data. Results reveal homogeneity both within and between regions for most skeletal indicators. However, MCR individuals exhibit a higher frequency of pathology than those from ETC, while stature is significantly lower in younger subadults from the MCR. Within the ETR, there is no evidence for biological differences between Early Dallas and subsequent Late Dallas and Mouse Creek cultural phases. Despite presumed signs of increased conflict at the Dallas site, frequencies and types of skeletal pathology and growth disruptions are comparable to other regional sites. These findings suggest that despite cultural differences between the ETR and MCR, there was no large-scale intrusion from an outside population into the ETR during the Late Mississippian Period, or if one occurred, it is biologically invisible. Combined with climatic and archaeobotanical data, results suggest the MCR subadults were under increased stress in their earlier years. This may have been associated with increased interpersonal violence and dependence on few food sources occurring with greater scarcity. © 2018 Wiley Periodicals, Inc.

  8. Assessment of salt concentration in bread commonly consumed in the Eastern Mediterranean Region.

    Science.gov (United States)

    Al Jawaldeh, Ayoub; Al-Khamaiseh, Manal

    2018-04-05

    Hypertension is the most important cardiovascular risk factor in the World Health Organization (WHO) Eastern Mediterranean Region. Excessive salt and sodium intake is directly related to hypertension, and its reduction is a priority of WHO. Bread is the leading staple food in the Region; therefore, reducing the amount of salt added to bread could be an effective measure for reducing salt intake. The study sought to determine the levels of sodium and salt in locally produced staple bread from 8 countries in the Region. Bread samples were collected randomly from bakeries located in the capital cities of the selected countries. The samples were analysed for sodium content using atomic absorption spectroscopy. The mean salt content of breads varied from 4.28 g/kg in Jordan to 12.41 g/kg in Tunisia. The mean salt and sodium content in bread for all countries was 7.63 (SD 3.12) and 3.0 (SD 1.23) g/kg, respectively. The contribution of bread to daily salt intake varied considerably between countries, ranging from 1.3 g (12.5%) in Jordan to 3.7 g (33.5%) in Tunisia. Interventions to reduce population salt intake should target reduction of salt in bread in all countries. The amount of salt added to bread should be standardized and relevant legislation developed to guide bakers. Setting an upper limit for salt content in flat bread (pita or Arabic bread) at 0.5% is strongly recommended. However, salt levels at ≤ 1% would be appropriate for other kind of breads. Copyright © World Health Organization (WHO) 2018. Some rights reserved. This work is available under the CC BY-NC-SA 3.0 IGO license (https://creativecommons.org/licenses/by-nc-sa/3.0/igo).

  9. IMPACT OF THE FINANCIAL CRISIS UPON EASTERN EUROPE COUNTRIES: STILL A PROBLEM FOR THE ECONOMY OF THE REGION?

    Directory of Open Access Journals (Sweden)

    MIHAELA-ANDREEA STROE

    2011-04-01

    Full Text Available The paper looks at the impact of the global economic and financial crisis on a number of central, eastern and south-eastern European countries. The global crisis can be viewed as three interdependent and mutually reinforcing crises: a financial crisis, a liquidity crisis, and a crisis in the real economy. The financial crises that have emerged and developed in the recent decades have been characterized, mostly of an international dimension, with shocks quickly propagating through capital markets, through the international banking activities and, through the money markets.East Europe was hit first by the global liquidity crisis, then by declines in capital inflows and plunging demand for their exports.Before the crisis, the Eastern region was experiencing an economic boom with rapid GDP and credit growth, but in the future East European countries will have to rely relatively more on internally-generated sources of productivity growth.

  10. The Arctic Marine Pulses Model: Linking Contiguous Domains in the Pacific Arctic Region

    Science.gov (United States)

    Moore, S. E.; Stabeno, P. J.

    2016-02-01

    The Pacific Arctic marine ecosystem extends from the northern Bering Sea, across the Chukchi and into the East Siberian and Beaufort seas. Food webs in this domain are short, a simplicity that belies the biophysical complexity underlying trophic linkages from primary production to humans. Existing biophysical models, such as pelagic-benthic coupling and advective processes, provide frameworks for connecting certain aspects of the marine food web, but do not offer a full accounting of events that occur seasonally across the Pacific Arctic. In the course of the Synthesis of Arctic Research (SOAR) project, a holistic Arctic Marine Pulses (AMP) model was developed that depicts seasonal biophysical `pulses' across a latitudinal gradient, and linking four previously-described contiguous domains, including the: (i) Pacific-Arctic domain = the focal region; (ii) seasonal ice zone domain; (iii) Pacific marginal domain; and (iv) riverine coastal domain. The AMP model provides a spatial-temporal framework to guide research on dynamic ecosystem processes during this period of rapid biophysical changes in the Pacific Arctic. Some of the processes included in the model, such as pelagic-benthic coupling in the Northern Bering and Chukchi seas, and advection and upwelling along the Beaufort shelf, are already the focus of sampling via the Distributed Biological Observatory (DBO) and other research programs. Other aspects such as biological processes associated with the seasonal ice zone and trophic responses to riverine outflow have received less attention. The AMP model could be enhanced by the application of visualization tools to provide a means to watch a season unfold in space and time. The capability to track sea ice dynamics and water masses and to move nutrients, prey and upper-trophic predators in space and time would provide a strong foundation for the development of predictive human-inclusive ecosystem models for the Pacific Arctic.

  11. Sonic hedgehog lineage in the mouse hypothalamus: from progenitor domains to hypothalamic regions

    Directory of Open Access Journals (Sweden)

    Alvarez-Bolado Gonzalo

    2012-01-01

    Full Text Available Abstract Background The hypothalamus is a brain region with essential functions for homeostasis and energy metabolism, and alterations of its development can contribute to pathological conditions in the adult, like hypertension, diabetes or obesity. However, due to the anatomical complexity of the hypothalamus, its development is not well understood. Sonic hedgehog (Shh is a key developmental regulator gene expressed in a dynamic pattern in hypothalamic progenitor cells. To obtain insight into hypothalamic organization, we used genetic inducible fate mapping (GIFM to map the lineages derived from Shh-expressing progenitor domains onto the four rostrocaudally arranged hypothalamic regions: preoptic, anterior, tuberal and mammillary. Results Shh-expressing progenitors labeled at an early stage (before embryonic day (E9.5 contribute neurons and astrocytes to a large caudal area including the mammillary and posterior tuberal regions as well as tanycytes (specialized median eminence glia. Progenitors labeled at later stages (after E9.5 give rise to neurons and astrocytes of the entire tuberal region and in particular the ventromedial nucleus, but not to cells in the mammillary region and median eminence. At this stage, an additional Shh-expressing domain appears in the preoptic area and contributes mostly astrocytes to the hypothalamus. Shh-expressing progenitors do not contribute to the anterior region at any stage. Finally, we show a gradual shift from neurogenesis to gliogenesis, so that progenitors expressing Shh after E12.5 generate almost exclusively hypothalamic astrocytes. Conclusions We define a fate map of the hypothalamus, based on the dynamic expression of Shh in the hypothalamic progenitor zones. We provide evidence that the large neurogenic Shh-expressing progenitor domains of the ventral diencephalon are continuous with those of the midbrain. We demonstrate that the four classical transverse zones of the hypothalamus have clearly

  12. Water chemistry in the rives of the permafrost regions on the eastern Qinghai-Tibetan Plateau

    Science.gov (United States)

    Wu, X.; Ma, X.; Ye, L.; Liu, G.

    2017-12-01

    Qinghai-Tibetan is the largest middle-low latitude permafrost areas on the world. There are several large rivers in the plateau, and the changes of the water resources of these rivers are associated with the water resource security of more than 1.35 billion people. Due to the high gradients, these rivers have a tremendous amount of potential energy for electricity output. To promote economic and social development and provide clean energy, hydropower development has taken place on several rivers which originate on the Qinghai-Tibetan Plateau. Since dam construction affect the flow velocity, water temperature, sediments delivery as well as organic matter and nitrogen, it is important to investigate the river chemistry in the head rivers of the reservoirs. We examined the water physio-chemical characteristics in the rivers under the typical vegetation types in the eastern Qinghai-Tibetan Plateau, and further analyzed their relationship to vegetation. The results showed that the total suspended sediment in the rivers were higher within the catchment of alpine steppe, with the lowest dissolved organic carbon content. In contrast, the rivers within the meadow had the highest dissolved organic carbon and lowest total suspension sediment. The dissolved organic carbon significantly positively correlated with the proportions of the meadow and wet meadow in the catchment. The pH, turbidity, and SUVA254 and dissolved organic carbon also correlated with each other. The results suggest that the vegetation type strongly affect the water chemistry in the permafrost regions on the Qinghai-Tibetan Plateau.

  13. Biological nitrogen fixation in the oxygen-minimum region of the eastern tropical North Pacific ocean.

    Science.gov (United States)

    Jayakumar, Amal; Chang, Bonnie X; Widner, Brittany; Bernhardt, Peter; Mulholland, Margaret R; Ward, Bess B

    2017-10-01

    Biological nitrogen fixation (BNF) was investigated above and within the oxygen-depleted waters of the oxygen-minimum zone of the Eastern Tropical North Pacific Ocean. BNF rates were estimated using an isotope tracer method that overcame the uncertainty of the conventional bubble method by directly measuring the tracer enrichment during the incubations. Highest rates of BNF (~4 nM day -1 ) occurred in coastal surface waters and lowest detectable rates (~0.2 nM day -1 ) were found in the anoxic region of offshore stations. BNF was not detectable in most samples from oxygen-depleted waters. The composition of the N 2 -fixing assemblage was investigated by sequencing of nifH genes. The diazotrophic assemblage in surface waters contained mainly Proteobacterial sequences (Cluster I nifH), while both Proteobacterial sequences and sequences with high identities to those of anaerobic microbes characterized as Clusters III and IV type nifH sequences were found in the anoxic waters. Our results indicate modest input of N through BNF in oxygen-depleted zones mainly due to the activity of proteobacterial diazotrophs.

  14. Ticks and Fleas Infestation on East Hedgehogs (Erinaceus concolor in Van Province, Eastern Region of Turkey

    Directory of Open Access Journals (Sweden)

    Yaşar Goz

    2015-10-01

    Full Text Available Background: Ixodid ticks (Acari: İxodidae and fleas (Siphonaptera are the major vectors of pathogens threatening animals and human healths. The aim of our study was to detect the infestation rates of East Hedgehogs (Erinaceus concolor with ticks and fleas in Van Province, eastern region of Turkey.Methods: We examined fleas and ticks infestation patterns in 21 hedgehogs, collected from three suburbs with the greater of number gardens. In order to estimate flea and tick infestation of hedgehogs, we immobilized the ectoparasites by treatment the body with a insecticide trichlorphon (Neguvon®-Bayer.Results: On the hedgehogs, 60 ixodid ticks and 125 fleas were detected. All of the ixodid ticks were Rhipicephalus turanicus and all of the fleas were Archaeopsylla erinacei. Infestation rate for ticks and fleas was detected 66.66 % and 100 %, respectively.Conclusion: We detected ticks (R. turanicus and fleas (A. erinacei in hedgehogs at fairly high rates. Since many ticks and fleas species may harbor on hedgehogs and transmit some tick-borne and flea-borne patogens, this results are the important in terms of veterinary and public health. 

  15. Natural and artificial radioactivity measurements in Eastern Black Sea region of Turkey

    International Nuclear Information System (INIS)

    Celik, N.; Cevik, U.; Celik, A.; Koz, B.

    2009-01-01

    In the present work, naturally occurring radionuclides of 226 Ra, 232 Th and 40 K were measured in soil samples collected from the Eastern Black Sea region of Turkey. It was found that the activity concentrations ranged from 12 to 120 Bq kg -1 for 226 Ra, from 13 to 121 Bq kg -1 for 232 Th and from 204 to 1295 Bq kg -1 for 40 K. Besides naturally occurring radionuclides, 137 Cs activity concentration was measured in soil, lichen and moss samples and it was found that 137 Cs activity concentration ranged from 27 to 775 Bq kg -1 with for soil, from 29 to 879 Bq kg -1 for lichen and from 67 to 1396 Bq kg -1 for moss samples. Annual effective doses due to the naturally occurring radionuclides and 137 Cs were estimated. Ecological half-lives of 137 Cs in lichen and moss species were estimated. The decrease of the activity concentrations in the present measurements (2007) relative to those in 1993 indicated ecological half-lives between 1.36 and 2.96 years for lichen and between 1.35 and 2.85 years for moss species

  16. A MORPHOLOGICAL STUDY OF HUMAN THYROID GLAND IN THE POPULATION OF NORTH - EASTERN REGION OF INDIA

    Directory of Open Access Journals (Sweden)

    Debabani

    2015-06-01

    Full Text Available BACKGROUND : Due to the high incidence of thyroid disorders in the North - Eastern population of India a study was undertaken in Guwahati Medical College to see the age related changes in the morphology of the gland in the ca davers of this region. AIM : The study was done to compare the dimensions of the thyroid gland in this population with different studies around the world to see if it can throw any light why thyroid disorders are more common in this population and help clin icians to deal better. MATERIALS AND METHOD : The specimens were divided into three groups according to their ages. Twenty (21 specimens (both male and female were taken from each age group. Statistical analysis was done by paired t - test and t was taken a s significant if the value of t was greater than 2.18. SUMMARY : A study of all together of 63 specimen were taken up to see if any morphological differences in dimension exists in various age groups viz. pediatrics , adults and elderly and co relate with fi ndings of previous workers and was statistically analyzed. CONCLUSION : The study showed that there was no morphological difference of this population with that of previous studies done in other parts of the world. Perhaps a histological study in molecular level will throw more light why this stratum of population is so vulnerable to thyroid disorders.

  17. Perception of Corporate Social Responsibility in companies of Eastern Slovakia region in 2009 and 2010

    Directory of Open Access Journals (Sweden)

    Iveta Ubrežiová

    2013-01-01

    Full Text Available The article deals with the perception of Corporate Social Responsibility in companies of Eastern Slovakia region in 2009 and 2010. It aims to evaluate the survey performed in selected companies with the aim to find answers to the research questions (concerning the rate of perception of Corporate Social Responsibility, the evaluation of using a concept in the company, the importance of engagement in this area and so on and with the assistance of selected methods for the examination. Different companies have framed different definition. Our own definition is that Corporate Social Responsibility is about how companies manage the business processes, to produce an overall positive impact on society. Holme said that Corporate Social Responsibility is the continuing commitment by business to behave ethically and contribute to economic development while improving the quality of life of the workforce and their families as well as of the local community and society. Stakeholders are persons, groups or organizations that has direct or indirect stake in companies actions, objectives and policies (include creditor’s customers, directors, employees, government, owners, suppliers, unions and the community. Based on findings and a comparison of the results is made focusing on stakeholder’s area, and suggestions are offered for the improvement in areas examined.

  18. The impact of work-related stress on medication errors in Eastern Region Saudi Arabia.

    Science.gov (United States)

    Salam, Abdul; Segal, David M; Abu-Helalah, Munir Ahmad; Gutierrez, Mary Lou; Joosub, Imran; Ahmed, Wasim; Bibi, Rubina; Clarke, Elizabeth; Qarni, Ali Ahmed Al

    2018-05-07

    To examine the relationship between overall level and source-specific work-related stressors on medication errors rate. A cross-sectional study examined the relationship between overall levels of stress, 25 source-specific work-related stressors and medication error rate based on documented incident reports in Saudi Arabia (SA) hospital, using secondary databases. King Abdulaziz Hospital in Al-Ahsa, Eastern Region, SA. Two hundred and sixty-nine healthcare professionals (HCPs). The odds ratio (OR) and corresponding 95% confidence interval (CI) for HCPs documented incident report medication errors and self-reported sources of Job Stress Survey. Multiple logistic regression analysis identified source-specific work-related stress as significantly associated with HCPs who made at least one medication error per month (P stress were two times more likely to make at least one medication error per month than non-stressed HCPs (OR: 1.95, P = 0.081). This is the first study to use documented incident reports for medication errors rather than self-report to evaluate the level of stress-related medication errors in SA HCPs. Job demands, such as social stressors (home life disruption, difficulties with colleagues), time pressures, structural determinants (compulsory night/weekend call duties) and higher income, were significantly associated with medication errors whereas overall stress revealed a 2-fold higher trend.

  19. Postglacial uplift of the eastern Gulf of Finland-Lake Ladoga region: models and observations

    Science.gov (United States)

    Amantov, Aleksey; Fjeldskaar, Willy; Amantova, Marina

    2015-04-01

    The eastern Gulf of Finland - Lake Ladoga region - is at the peripheral part of the Fennoscandian post-glacial uplift. We compared different modeling results for this region with observations, including our revision of geomorphological traces of paleo shorelevel. As in many parts of the general Baltic-White Sea bedrock lowland at the margin of the Fennoscandian Shield, the bedrock landscape was modified by glaciers, but it was also the major controlling factor for the history of glacial grows and decays. First-order landforms of this segment are: Lake Ladoga-Lake Ilmen lowland, Lembolovo High of the Karelic Isthmus and Neva-Gulf of Finland lowland. The range of the bedrock topography is close to 350 m. The landforms reflect different glacial behavior during stadials, with fast movement and strong erosion in northern Ladoga, but passive motion and accumulation around Lembolovo High. The differences influenced the ice sheet and deglaciation history. The shore level displacements in this area are slightly different than westwards in the Baltic area; the shoreline tilts are usually lower in southern-central part of the eastern Gulf of Finland-lake Ladoga region. For example, the shoreline tilts at 11 600 BP in the Baltic Ice Lake in the south-east range from 0.55 to 0.31 m/km. The slope of the Ancylus shoreline varies from 0.12 to 0.18 m/km, increasing to almost the double in the north-western area. Similarly, the Littorina shore level is tilted only 0.08 m/km, rising to 0.14 m/km in the north-west. We have used this data in our high resolution modeling involving glacial isostasy, hydro isostasy, sediment isostasy, and gravity field changes. The mopdeling is based on Earth rheology model with a low-viscosity asthenosphere of thickness less than 150 km and viscosity less than 7.0x10**19 Pa s above a mantle of viscosity 10**21 Pa s, and an effective elastic lithosphere thickness of 30-40 km (flexural rigidity 10**24 Nm). The specific uplift features in the area are

  20. Mesozooplankton respiration and community structure in a seamount region of the eastern South Pacific

    Science.gov (United States)

    Frederick, Leissing; Escribano, Ruben; Morales, Carmen E.; Hormazabal, Samuel; Medellín-Mora, Johanna

    2018-05-01

    Seamounts in the Juan Fernandez Ridge, as well as in other seamount regions in the eastern South Pacific and in the world oceans, remain poorly studied ecosystems in terms of structure and functioning. Here, community respiration by epipelagic mesozooplankton in three seamounts of the Juan Fernandez Ridge, including the O`Higgins Seamount close to the coastal upwelling zone and two oceanic seamounts near the Juan Fernandez Archipelago ( 33°S-78°W), was assessed. Oxygen consumption by mixed assemblages was estimated using continuous measurements of dissolved oxygen concentration under controlled temperature during onboard, short-term incubations (2-4 h). Mesozooplankton composition was analyzed with a ZooScan device and expressed in terms of community normalized size spectra, and taxa and size diversity (Shannon-Wiener index). Carbon-specific community respiration rates in the upper 100 m layer were in the range of 0.3-1.9 mg O2 m-2 d-1, indicating that up to 3.1% of the mesozooplankton biomass can be respired on a daily basis. The mesozooplankton community was dominated by small-size copepods but the proportions of small copepods, large copepods, and gelatinous zooplankton (mostly salps) changed between the seamounts, in association with modifications in taxa composition, size diversity, and the slope of the size spectrum. Community respiration was significantly correlated to these community descriptors, suggesting the composition of the pelagic community has a direct impact on the total amount of respired-C. Connectivity between the coastal upwelling zone and the Juan Fernandez Ridge region mediated by mesoscale activity, interacting with the seamounts, is suggested as a most important process in controlling zooplankton community structure and in turn community metabolism.

  1. Prevalence and risk factors associated with nutrition-related noncommunicable diseases in the Eastern Mediterranean region

    Science.gov (United States)

    Musaiger, Abdulrahman O; Al-Hazzaa, Hazzaa M

    2012-01-01

    This paper reviews the current situation concerning nutrition-related noncommunicable diseases (N-NCDs) and the risk factors associated with these diseases in the Eastern Mediterranean region (EMR). A systematic literature review of studies and reports published between January 1, 1990 and September 15, 2011 was conducted using the PubMed and Google Scholar databases. Cardiovascular disease, type 2 diabetes, metabolic syndrome, obesity, cancer, and osteoporosis have become the main causes of morbidity and mortality, especially with progressive aging of the population. The estimated mortality rate due to cardiovascular disease and diabetes ranged from 179.8 to 765.2 per 100,000 population, with the highest rates in poor countries. The prevalence of metabolic syndrome was very high, ranging from 19% to 45%. The prevalence of overweight and obesity (body mass index ≥25 kg/m2) has reached an alarming level in most countries of the region, ranging from 25% to 82%, with a higher prevalence among women. The estimated mortality rate for cancer ranged from 61.9 to 151 per 100,000 population. Osteoporosis has become a critical problem, particularly among women. Several risk factors may be contributing to the high prevalence of N-NCDs in EMR, including nutrition transition, low intake of fruit and vegetables, demographic transition, urbanization, physical inactivity, hypertension, tobacco smoking, stunting of growth of preschool children, and lack of nutrition and health awareness. Intervention programs to prevent and control N-NCDs are urgently needed, with special focus on promotion of healthy eating and physical activity. PMID:22399864

  2. Assessment of the Baby Friendly Hospital Initiative Implementation in the Eastern Mediterranean Region.

    Science.gov (United States)

    Al-Jawaldeh, Ayoub; Abul-Fadl, Azza

    2018-03-11

    The Baby-Friendly Hospital Initiative (BFHI) is a global program for promoting support and protection for breastfeeding. However, its impact on malnutrition, especially in countries of the Eastern Mediterranean region (EMR) that are facing the turmoil of conflict and emergencies, deserves further investigation. Having said that, this paper aims to discuss the status and challenges to BFHI implementation in the EMR countries. Data on BFHI implementation, breastfeeding practices, and nutritional status were collected from countries through structured questionnaires, personal interviews, and databases. The 22 countries of the EMR were categorized as follows: 8 countries in advanced nutrition transition stage (group I), 5 countries in early nutrition transition stage (group II), 4 countries with significant undernutrition (group III), and 5 countries in complex emergency (group IV). The challenges to BFHI implementation were discussed in relation to malnutrition. BFHI was not implemented in 22.7% of EMR countries. Designated Baby-Friendly hospitals totaled 829 (group I: 78.4%, group II: 9.05%; group III: 7.36%; group: IV5.19%). Countries with advanced nutrition transition had the highest implementation of BFHI but the lowest breastfeeding continuity rates. On the other hand, poor nutritional status and emergency states were linked with low BFHI implementation and low exclusive breastfeeding rates but high continuity rates. Early initiation and longer duration of breastfeeding correlated negatively with overweight and obesity ( p < 0.001). In countries with emergency states, breastfeeding continues to be the main source of nourishment. However, suboptimal breastfeeding practices prevail because of poor BFHI implementation which consequently leads to malnutrition. Political willpower and community-based initiatives are needed to promote breastfeeding and strengthen BFHI in the region.

  3. Assessment of the Baby Friendly Hospital Initiative Implementation in the Eastern Mediterranean Region

    Directory of Open Access Journals (Sweden)

    Ayoub Al-Jawaldeh

    2018-03-01

    Full Text Available The Baby-Friendly Hospital Initiative (BFHI is a global program for promoting support and protection for breastfeeding. However, its impact on malnutrition, especially in countries of the Eastern Mediterranean region (EMR that are facing the turmoil of conflict and emergencies, deserves further investigation. Having said that, this paper aims to discuss the status and challenges to BFHI implementation in the EMR countries. Data on BFHI implementation, breastfeeding practices, and nutritional status were collected from countries through structured questionnaires, personal interviews, and databases. The 22 countries of the EMR were categorized as follows: 8 countries in advanced nutrition transition stage (group I, 5 countries in early nutrition transition stage (group II, 4 countries with significant undernutrition (group III, and 5 countries in complex emergency (group IV. The challenges to BFHI implementation were discussed in relation to malnutrition. BFHI was not implemented in 22.7% of EMR countries. Designated Baby-Friendly hospitals totaled 829 (group I: 78.4%, group II: 9.05%; group III: 7.36%; group: IV5.19%. Countries with advanced nutrition transition had the highest implementation of BFHI but the lowest breastfeeding continuity rates. On the other hand, poor nutritional status and emergency states were linked with low BFHI implementation and low exclusive breastfeeding rates but high continuity rates. Early initiation and longer duration of breastfeeding correlated negatively with overweight and obesity (p < 0.001. In countries with emergency states, breastfeeding continues to be the main source of nourishment. However, suboptimal breastfeeding practices prevail because of poor BFHI implementation which consequently leads to malnutrition. Political willpower and community-based initiatives are needed to promote breastfeeding and strengthen BFHI in the region.

  4. Assessment of the Baby Friendly Hospital Initiative Implementation in the Eastern Mediterranean Region

    Science.gov (United States)

    Al-Jawaldeh, Ayoub; Abul-Fadl, Azza

    2018-01-01

    The Baby-Friendly Hospital Initiative (BFHI) is a global program for promoting support and protection for breastfeeding. However, its impact on malnutrition, especially in countries of the Eastern Mediterranean region (EMR) that are facing the turmoil of conflict and emergencies, deserves further investigation. Having said that, this paper aims to discuss the status and challenges to BFHI implementation in the EMR countries. Data on BFHI implementation, breastfeeding practices, and nutritional status were collected from countries through structured questionnaires, personal interviews, and databases. The 22 countries of the EMR were categorized as follows: 8 countries in advanced nutrition transition stage (group I), 5 countries in early nutrition transition stage (group II), 4 countries with significant undernutrition (group III), and 5 countries in complex emergency (group IV). The challenges to BFHI implementation were discussed in relation to malnutrition. BFHI was not implemented in 22.7% of EMR countries. Designated Baby-Friendly hospitals totaled 829 (group I: 78.4%, group II: 9.05%; group III: 7.36%; group: IV5.19%). Countries with advanced nutrition transition had the highest implementation of BFHI but the lowest breastfeeding continuity rates. On the other hand, poor nutritional status and emergency states were linked with low BFHI implementation and low exclusive breastfeeding rates but high continuity rates. Early initiation and longer duration of breastfeeding correlated negatively with overweight and obesity (p < 0.001). In countries with emergency states, breastfeeding continues to be the main source of nourishment. However, suboptimal breastfeeding practices prevail because of poor BFHI implementation which consequently leads to malnutrition. Political willpower and community-based initiatives are needed to promote breastfeeding and strengthen BFHI in the region. PMID:29534482

  5. Aeolian processes during the Holocene in Gannan Region, Eastern Tibetan Plateau

    Science.gov (United States)

    Yang, S.; Cheng, T.; Li, S.; Liang, M.

    2016-12-01

    Aeolian desertification occurring in the Tibetan Plateau has received attention recently for it has become a severe environmental problem by accelerating the grassland degradation and eco-environment damage. The Gannan Region is located in the northeastern Tibetan Plateau with a mean altitude of 3500m. It is highly sensitive to global environmental change and human disturbance. Serious soil erosion and desertification and extensive land degradation have caused heavy eco-environmental impacts. To investigate the evolution of the desertification in Holocene in the Plateau is of great importance for understanding the desertification trend under the global changes in the Tibetan Plateau. Loess and aeolian sands is a key geological archive related to desertification processes and the past environment changes. In this study a typical 8.5m-thick loess-sands profile named MQQ, was selected at the Maqu city. It is situated on the first terrace (T1) of the Yellow River. Detailed accelerator mass spectrometry (AMS) 14C dating of bulk organic matter content has shown the Aeolian sediments of the MQQ section occurring since the early Holocene. the mass-specific frequency-dependent magnetic susceptibility (χfd) and grainsize records show a clear upward increase in the contents of superparamagnetic grains and fine fractions in grain size, which indicates a gradual wetting trend during the Holocene.The sediment rates change from very high in the early Holocene to low values after 8.2 ka. The wetting process can be divided into three steps: 10.0-8.2 ka, 8.2-3.0 ka and 3.0-present. It indicates that the climate in the eastern Tibetan Plateau was dry during the early Holocene. After that the climate was getting wet gradually. The variations of the westerlies and the Asian monsoon may cause the environmental change in this region.

  6. Family planning use and associated factors among pastoralist community of afar region, eastern Ethiopia.

    Science.gov (United States)

    Alemayehu, Mussie; Lemma, Hailemariam; Abrha, Kidan; Adama, Yohannes; Fisseha, Girmatsion; Yebyo, Henock; Gebeye, Ejigu; Negash, Kassahun; Yousuf, Jemal; Fantu, Tigist; Gebregzabher, Tesfay; Medhanyie, Araya Abrha

    2016-07-18

    Ethiopia is the second most populous country in Africa with a total fertility rate (TFR) of 4.8 children per a woman and contraceptive prevalence rate (CPR) of 29 %. The overall prevalence of modern family planning in a pastoralist community, like Afar region, is low (9.1 %). This study aimed to assess family planning utilization and associated factors among married women of Afar region, Eastern Ethiopia. A community-based cross-sectional study was conducted from January 10-28, 2013 among 602 women. Multistage sampling technique was used to select the study participants. Descriptive and multiple variable logistic regression analyses were done to isolate independent predictors on utilization of family planning using SPSS 20. The overall prevalence of family planning utilization in Afar region was 8.5 % (6.2-10.7). Majority of the women (92.2 %) had used injectable. The most common reasons mentioned in the non-use of family planning methods were religion-related (85.3 %), desire to have more children (75.3 %), and husband's objection (70.1 %). Women who had a positive attitude towards family planning utilization (AOR = 4.7, 95 % CI: 2.1, 10.3), owning radio (AOR = 1.8, 95 % CI: 1.02, 4.18), and literate (AOR = 4.4, 95 % CI: 1.80, 11.08) were more likely to use family planning methods as compared to their counterparts. The increase of monthly income was also associated with the likelihood of family planning methods utilization. The odds of using family planning methods were higher among those with monthly income of $27-$55.5 (AOR = 2. 0, 95 % CI: 1.9, 4.7) and > $55 (AOR = 4. 6, 95 % CI: 1.23-17.19) as compared to women with the lowest category of monthly income ($27 and less). The low coverage of family planning in the region could be due to the influence of husband, religious and clan leader. Attitude of women towards family planning methods, possession of radio, monthly income, and educational status could influence family

  7. Sediment grain-size characteristics and relevant correlations to the aeolian environment in China's eastern desert region.

    Science.gov (United States)

    Zhang, Chunlai; Shen, Yaping; Li, Qing; Jia, Wenru; Li, Jiao; Wang, Xuesong

    2018-06-15

    To identify characteristics of aeolian activity and the aeolian environment in China's eastern desert region, this study collected surface sediment samples from the main desert and sandy lands in this region: the Hobq Desert and the Mu Us, Otindag, Horqin, and Hulunbuir sandy lands. We analyzed the grain-size characteristics and their relationships to three key environmental indicators: drift potential, the dune mobility index, and vegetation cover. The main sediment components are fine to medium sands, with poor (Hulunbuir) to moderate (all other areas) sorting, of unimodal to bimodal distribution. This suggests that improved sorting is accomplished by the loss of both relatively coarser and finer grains. Since 2000, China's eastern desert region has generally experienced low wind energy environmental conditions, resulting in decreased dune activity. In the Hobq Desert, however, the dry climate and sparse vegetation, in conjunction with the most widely distributed mobile dune area in the eastern desert region, have led to frequent and intense aeolian activity, including wind erosion, sand transport, and deposition, resulting in conditions for good sediment sorting. In the Mu Us, Otindag, and Horqin sandy lands, mosaic distribution has resulted from wind erosion-dominated and deposition-dominated aeolian environments. In the Hulunbuir Sandy Land, high precipitation, low temperatures, and steppe vegetation have resulted in well-developed soils; however, strong winds and flat terrain have created an aeolian environment dominated by wind erosion. Copyright © 2018. Published by Elsevier B.V.

  8. Domain-General Brain Regions Do Not Track Linguistic Input as Closely as Language-Selective Regions.

    Science.gov (United States)

    Blank, Idan A; Fedorenko, Evelina

    2017-10-11

    Language comprehension engages a cortical network of left frontal and temporal regions. Activity in this network is language-selective, showing virtually no modulation by nonlinguistic tasks. In addition, language comprehension engages a second network consisting of bilateral frontal, parietal, cingulate, and insular regions. Activity in this "multiple demand" (MD) network scales with comprehension difficulty, but also with cognitive effort across a wide range of nonlinguistic tasks in a domain-general fashion. Given the functional dissociation between the language and MD networks, their respective contributions to comprehension are likely distinct, yet such differences remain elusive. Prior neuroimaging studies have suggested that activity in each network covaries with some linguistic features that, behaviorally, influence on-line processing and comprehension. This sensitivity of the language and MD networks to local input characteristics has often been interpreted, implicitly or explicitly, as evidence that both networks track linguistic input closely, and in a manner consistent across individuals. Here, we used fMRI to directly test this assumption by comparing the BOLD signal time courses in each network across different people ( n = 45, men and women) listening to the same story. Language network activity showed fewer individual differences, indicative of closer input tracking, whereas MD network activity was more idiosyncratic and, moreover, showed lower reliability within an individual across repetitions of a story. These findings constrain cognitive models of language comprehension by suggesting a novel distinction between the processes implemented in the language and MD networks. SIGNIFICANCE STATEMENT Language comprehension recruits both language-specific mechanisms and domain-general mechanisms that are engaged in many cognitive processes. In the human cortex, language-selective mechanisms are implemented in the left-lateralized "core language network

  9. Desmodium: A low-cost pasture for the eastern Cape coastal region ...

    African Journals Online (AJOL)

    Keywords: Animal production; Beef production; botany; Desmodium intortum; dryland; east london; Eastern Cape; economic evaluation; fertilizer; grasses; gross margin; Growth requirements; livestock; Management; maximum production; pasture; Pastures; Production costs; south africa; star grass; stocking rate; stocking ...

  10. Characteristics of long-period swells measured in the near shore regions of eastern Arabian Sea

    Digital Repository Service at National Institute of Oceanography (India)

    Johnson, G.; SanilKumar, V.; Amrutha, M.M.; Singh, J.

    Measured wave data covering two years simultaneously at 3 locations along the eastern Arabian Sea reveals the presence of long-period (peak wave period > 18 s) low-amplitude waves (significant wave height < 1 m) and the characteristics...

  11. The Burden of Mental Disorders in the Eastern Mediterranean Region, 1990-2013

    Science.gov (United States)

    Charara, Raghid; Forouzanfar, Mohammad; Naghavi, Mohsen; Moradi-Lakeh, Maziar; Afshin, Ashkan; Vos, Theo; Daoud, Farah; Wang, Haidong; El Bcheraoui, Charbel; Khalil, Ibrahim; Hamadeh, Randah R.; Khosravi, Ardeshir; Rahimi-Movaghar, Vafa; Khader, Yousef; Al-Hamad, Nawal; Makhlouf Obermeyer, Carla; Rafay, Anwar; Asghar, Rana; Rana, Saleem M.; Shaheen, Amira; Abu-Rmeileh, Niveen M. E.; Husseini, Abdullatif; Abu-Raddad, Laith J.; Khoja, Tawfik; Al Rayess, Zulfa A.; AlBuhairan, Fadia S.; Hsairi, Mohamed; Alomari, Mahmoud A.; Ali, Raghib; Roshandel, Gholamreza; Terkawi, Abdullah Sulieman; Hamidi, Samer; Refaat, Amany H.; Westerman, Ronny; Kiadaliri, Aliasghar Ahmad; Akanda, Ali S.; Ali, Syed Danish; Bacha, Umar; Badawi, Alaa; Bazargan-Hejazi, Shahrzad; Faghmous, Imad A. D.; Fereshtehnejad, Seyed-Mohammad; Fischer, Florian; Jonas, Jost B.; Kuate Defo, Barthelemy; Mehari, Alem; Omer, Saad B.; Pourmalek, Farshad; Uthman, Olalekan A.; Mokdad, Ali A.; Maalouf, Fadi T.; Abd-Allah, Foad; Akseer, Nadia; Arya, Dinesh; Borschmann, Rohan; Brazinova, Alexandra; Brugha, Traolach S.; Catalá-López, Ferrán; Degenhardt, Louisa; Ferrari, Alize; Haro, Josep Maria; Horino, Masako; Hornberger, John C.; Huang, Hsiang; Kieling, Christian; Kim, Daniel; Kim, Yunjin; Knudsen, Ann Kristin; Mitchell, Philip B.; Patton, George; Sagar, Rajesh; Satpathy, Maheswar; Savuon, Kim; Seedat, Soraya; Shiue, Ivy; Skogen, Jens Christoffer; Stein, Dan J.; Tabb, Karen M.; Whiteford, Harvey A.; Yip, Paul; Yonemoto, Naohiro; Murray, Christopher J. L.; Mokdad, Ali H.

    2017-01-01

    The Eastern Mediterranean Region (EMR) is witnessing an increase in chronic disorders, including mental illness. With ongoing unrest, this is expected to rise. This is the first study to quantify the burden of mental disorders in the EMR. We used data from the Global Burden of Disease study (GBD) 2013. DALYs (disability-adjusted life years) allow assessment of both premature mortality (years of life lost–YLLs) and nonfatal outcomes (years lived with disability–YLDs). DALYs are computed by adding YLLs and YLDs for each age-sex-country group. In 2013, mental disorders contributed to 5.6% of the total disease burden in the EMR (1894 DALYS/100,000 population): 2519 DALYS/100,000 (2590/100,000 males, 2426/100,000 females) in high-income countries, 1884 DALYS/100,000 (1618/100,000 males, 2157/100,000 females) in middle-income countries, 1607 DALYS/100,000 (1500/100,000 males, 1717/100,000 females) in low-income countries. Females had a greater proportion of burden due to mental disorders than did males of equivalent ages, except for those under 15 years of age. The highest proportion of DALYs occurred in the 25–49 age group, with a peak in the 35–39 years age group (5344 DALYs/100,000). The burden of mental disorders in EMR increased from 1726 DALYs/100,000 in 1990 to 1912 DALYs/100,000 in 2013 (10.8% increase). Within the mental disorders group in EMR, depressive disorders accounted for most DALYs, followed by anxiety disorders. Among EMR countries, Palestine had the largest burden of mental disorders. Nearly all EMR countries had a higher mental disorder burden compared to the global level. Our findings call for EMR ministries of health to increase provision of mental health services and to address the stigma of mental illness. Moreover, our results showing the accelerating burden of mental health are alarming as the region is seeing an increased level of instability. Indeed, mental health problems, if not properly addressed, will lead to an increased burden of

  12. Regional trend analysis of surface ozone observations from monitoring networks in eastern North America, Europe and East Asia

    Science.gov (United States)

    Chang, K. L.; Petropavlovskikh, I. V.; Cooper, O. R.; Schultz, M.; Wang, T.

    2017-12-01

    Surface ozone is a greenhouse gas and pollutant detrimental to human health and crop and ecosystem productivity. The Tropospheric Ozone Assessment Report (TOAR) is designed to provide the research community with an up-to-date observation-based overview of tropospheric ozone's global distribution and trends. The TOAR Surface Ozone Database contains ozone metrics at thousands of monitoring sites around the world, densely clustered across mid-latitude North America, western Europe and East Asia. Calculating regional ozone trends across these locations is challenging due to the uneven spacing of the monitoring sites across urban and rural areas. To meet this challenge we conducted a spatial and temporal trend analysis of several TOAR ozone metrics across these three regions for summertime (April-September) 2000-2014, using the generalized additive mixed model (GAMM). Our analysis indicates that East Asia has the greatest human and plant exposure to ozone pollution among investigating regions, with increasing ozone levels through 2014. The results also show that ozone mixing ratios continue to decline significantly over eastern North America and Europe, however, there is less evidence for decreases of daytime average ozone at urban sites. The present-day spatial coverage of ozone monitors in East Asia (South Korea and Japan) and eastern North America is adequate for estimating regional trends by simply taking the average of the individual trends at each site. However the European network is more sparsely populated across its northern and eastern regions and therefore a simple average of the individual trends at each site does not yield an accurate regional trend. This analysis demonstrates that the GAMM technique can be used to assess the regional representativeness of existing monitoring networks, indicating those networks for which a regional trend can be obtained by simply averaging the trends of all individual sites and those networks that require a more

  13. A regional multi-scale 3-D geological model of the Eastern Sub-Athabasca Basement, Canada: Implications for vectoring towards unconformity-type uranium deposits

    International Nuclear Information System (INIS)

    Annesley, I.; Reilkoff, B.; Takacs, E.; Hajnal, Z.; Pandit, B.

    2014-01-01

    The Proterozoic Athabasca Basin of northern Saskatchewan is one of the most important mining districts in Canada; hosting the world’s highest grade uranium deposits and prospects. In the basin, many of the near-surface deposits have been discovered; hence new ore deposits at greater depths need to be discovered. To help make new discoveries, 3D geological modelling is being carried out. Here, we present our multidisciplinary approach, whereby a 3D geological model of the eastern sub- Athabasca basement of northern Saskatchewan (i.e. the eastern and western Wollaston domains, the Wollaston-Mudjatik Transition Zone (WMTZ), and the Mudjatik Domain) was developed in the common earth environment. The project was directed towards building a robust 3D model(s) of the upper 3-5 km of the Earth’s crust in three different scales: deposit-, district-, and regional-scale, using the GOCAD software platform (Paradigm). Our eastern sub-Athabasca basement model is constrained by both geological studies and geophysical techniques, such as topographic, outcrop, drill hole, petrophysical, and petrological data, along with geophysical potential field, electrical, and highresolution regional seismic data, in order to better understand the regional- to district-scale tectonics and controls on the uranium mineral system(s) operating pre-, syn-, and post-Athabasca deposition. The resulting data were interpreted and visualized as 3D-surfaces and bodies in GOCAD. This model reveals a framework of key lithological contacts, major high-strain zones, and the setting of unconformity-type uranium deposits. As a result, this new knowledge is being used to identify key exploration vectoring criteria for unconformity-type, magmatic, and metamorphic/ metasomatic uranium deposits and to delineate new exploration targets in the basin. Hence, this regional-scale 3D GOCAD model can be utilized as a guide for exploration activities within the region (e.g. picking new drill targets). As well, this 3D

  14. Breakfast habits among school children in selected communities in the eastern region of Ghana.

    Science.gov (United States)

    Intiful, F D; Lartey, A

    2014-06-01

    Breakfast is considered the most important meal of the day, yet many people skip breakfast. Studies indicate that school age children who regularly skip breakfast are not likely to concentrate in class, thus affecting school performance. This study determined the breakfast habits and nutrient contributions of the breakfast meal to the days' nutrient intake. A cross sectional study was conducted among school children (n=359) between the ages of 6-19 years in Manya Krobo in the Eastern Region of Ghana. Questionnaires were used to collect information on background characteristics and breakfast consumption habits. The 24-hour dietary recall method was used to obtain information on the children's food intake. T-test was used to compare differences between means of variables of breakfast consumers and skippers. About 85.5% of the children had breakfast on the day of interview. More boys (87.8%) consumed breakfast compared to the girls (83.1%). For those who skipped breakfast, lack of food at home or lack of no money (36.5%) was the main reason. Breakfast consumers had significantly higher energy and nutrient intakes than those who skipped breakfast (energy 2259 verses 1360 kcal, p-0.039; vitamin A 1534 verses 662 ug/RE, p=0.001; iron 22.9 verses 13.9 mg, p=0.017, zinc 9.9 verses 5.6 mg, p=0.034). The breakfast meal contributed between 32-41% of the day's energy intake, and between 30-47% of micronutrient intake. Encouraging breakfast consumption among school children is a way to ensure that they meet their daily nutrient and energy intakes.

  15. Applications of aeromagnetic data to detect the Basement Tectonics of Eastern Yemen region

    Directory of Open Access Journals (Sweden)

    Ahmed S. Abu El-Ata

    2013-12-01

    Full Text Available The present study aims to throw light on the tectonic implications concerned with the distribution of the sedimentary sequence belts and the related basement complex zones, as well as to differentiate between the causative sources (contacts, dykes and faults of Eastern Yemen region. The total intensity aeromagnetic map of the study area was first corrected by the application of the Reduction To the magnetic pole (for low latitude areas. The visual inspection of the RTP magnetic map defines a rapid change in the subsurface geologic conditions in the form of lithologic characters and tectonic inferences. On the other hand, this map showed different anomalies of varying frequencies and amplitudes that revealed various causative sources, as well as varying compositions and depths. At the interpretation stage, various techniques and software tools are available for extracting the geologic information from the data concerned. The magnetic fields of shallow sources can be separated from those of deeper causatives, using two processes known as power spectrum transformation and matched band pass filtering. Three methods for locating magnetic sources (Magnitude of Horizontal Gradients (HGM, the analytical signals (AS and the local wavenumbers (LW in three dimensions and identifying the properties of their sources indicated that, the area was affected by some intrusions at various depths in sill or dyke forms, almost oriented in the NW–SE, NE–SW, E–W and N–S trends. Tectonically, the area is highly affected by the tectonics related to the Arabian Sea, Gulf of Aden and Red Sea. It is affecting both the basement and sedimentary rocks, dividing the study area into several faulted blocks.

  16. Spatial Profile of Poverty.Case Study:The North-Eastern Development Region in Romania

    Directory of Open Access Journals (Sweden)

    Andrei SCHVAB

    2015-06-01

    Full Text Available In the present study the authors try to em-phasize the interdependent relations that are established between space and poverty, as well as the modalities through which poverty policies can be optimized and implemented at the territo-rial systems level in accordance to the polycen-tric development model.The f rst goal of the study is to understand the way in which the complexity of the territory, in its structure and relations, inf uences in un-equal ways the territorial pattern of poverty and development. The concept of territorial poverty that we use in the present study transcends the usual connotation of poverty as a simple lack of different kind of resources towards the incapacity of the system to offer a wide range of impulses and solutions to the encountered problems and thus induce a state of underdevelopment.The second goal is to understand in which ways the polycentric development theory can play a role in reducing poverty. In this sense the authors created a poverty index, and based on this index a polycentric development model was created for the North-Eastern region. This poly-centric development model has direct implica-tions for policy makers, as it highlights the areas that require the most attention and the develop-ment pole that should inf uence its development. By taking into consideration the results of this study, the next logical step for policy makers is to implement the necessary measures by consider-ing the relations between the development pole and the underdeveloped area that is under its in-f uence area. In this respect tailor-f t policies and measures can be applied in the effort to reduce poverty levels.

  17. Records of the Genus Paramerina (Diptera: Chironomidae: Tanypodinae) from Eastern Himalaya and Satpura Hill Regions of India.

    Science.gov (United States)

    Paul, N; Hazra, N; Mazumdar, A

    2013-10-01

    The pupa and the male imago of Paramerina valida n. sp. and the larva of Paramerina inficia Chaudhuri & Debnath are described and illustrated along with a brief re-description of the adult of P. inficia from the Eastern Himalaya and Satpura hill regions of India. A key to the adult males of the Indian species of the genus Paramerina Fittkau is provided. The notes on ecology of the two species are also provided.

  18. From field to region yield predictions in response to pedo-climatic variations in Eastern Canada

    Science.gov (United States)

    JÉGO, G.; Pattey, E.; Liu, J.

    2013-12-01

    to improve regional crop modelling. Although several aspects of the coupling between crop models and RS data have been investigated (e.g., inversion of radiative transfer models and neural networks), extensive verification using multiple years and sites is required prior to implementation of the RS assimilation at the regional scale, in order to evaluate the model robustness and consistency in response to climatic variations. STICS performance was evaluated over several years for spring wheat, soybean and corn yield predictions over two small rainfed agricultural region of Eastern Canada exhibiting a high degree of pedodiversity when LAI derived from EO data was assimilated. Averaged yield predictions of the three crops compared well with measurements (10%

  19. A ˜50 ka record of monsoonal variability in the Darjeeling foothill region, eastern Himalayas

    Science.gov (United States)

    Ghosh, Ruby; Bera, Subir; Sarkar, Anindya; Paruya, Dipak Kumar; Yao, Yi-Feng; Li, Cheng-Sen

    2015-04-01

    Pollen, phytoliths and δ 13C signatures of soil organic matter from two fluvial sedimentary sequences of the Darjeeling foothill region, eastern Himalayas are used to portray palaeoclimatic oscillations and their impact on regional plant communities over the last ˜50 ka. Quantitative palaeoclimate estimation using coexistence approach on pollen data and other proxies indicate significant oscillations in precipitation during the late part of MIS 3 (46.4-25.9 ka), early and middle part of MIS 2 (25.9-15.6 ka), and 5.4 to 3.5 ka. Middle to late MIS 3 (ca 46.4-31 ka.) was characterized by a comparatively low monsoonal activity and slightly higher temperature than that during ca 31 ka onwards. Simultaneous expansion of deciduous trees and chloridoid grasses also imply a drier and warmer phase. Between 31 and 22.3 ka (late MIS 3 to mid-MIS 2), higher precipitation and a slightly cooler temperature led to an increase in evergreen elements over deciduous taxa and wet-loving panicoid grasses over dry-loving chloridoid grasses than earlier. After ca 22.3 ka, shrinking of forest cover, expansion of C4 chloridoid grasses, Asteraceae and Cheno-ams in the vegetation with lowering of temperature and precipitation characterized the onset of the LGM which continued till 18.3 ka. End of the LGM is manifested by a restoration in the forest cover and in the temperature and precipitation regime. Later, during 5.4 to 4.3 ka, a strong monsoonal activity supported a dense moist evergreen forest cover that subsequently declined during 4.3 to 3.5 ka. A further increase in deciduous elements and non-arboreals might be a consequence of reduced precipitation and higher temperature during this phase. A comparison between monsoonal rainfall, MAT and palaeoatmospheric CO2 with floral dynamics since last ˜50 ka indicates that these fluctuations in plant succession were mainly driven by monsoonal variations.

  20. The generation and selection of single-domain, v region libraries from nurse sharks.

    Science.gov (United States)

    Flajnik, Martin F; Dooley, Helen

    2009-01-01

    The cartilaginous fish (sharks, skates, and rays) are the oldest phylogenetic group in which a human-type adaptive immune system and immunoglobulins (Igs) have been found. In addition to their conventional (heavy-light chain heterodimeric) isotypes, IgM and IgW, sharks produce the novel isotype, IgNAR, a heavy chain homodimer that does not associate with light chains. Instead, its variable (V) regions act as independent, soluble units in order to bind antigen. In this chapter, we detail our immunization protocol in order to raise a humoral IgNAR response in the nurse shark (Ginglymostoma cirratum) and the subsequent cloning of the single-domain V regions from this isotype in order to select antigen-specific binders by phage display.

  1. Sustainability Organic Agriculture and Livestock Production with Respect to European Union in Eastern Anatolia and East Black Sea Regions

    Directory of Open Access Journals (Sweden)

    Vecihi Aksakal

    2016-11-01

    Full Text Available The majority of farm households in Turkey and especially the Eastern Anatolia are still based on low-input semi subsistence agriculture and livestock production. Despite a slow decline in recent years, agriculture and livestock production remains a major employer in Turkey and it is a significant contributor to the country’s gross domestic product, GDP. Whist Turkey is one of the EU candidate countries, is self sufficient in food production and Turkish agriculture is poorly structured inefficient, with farming in the Eastern Anatolia being mainly subsistence farming. Yet, these traditional rural structures combined with poor access to low level of education and low level of off-farm unemployment problem makes the situation more complicated and unsustainable. The best way to promote sustainability, better and higher production of Eastern Anatolian and rural Turkey is to invest in the local people, villages through improved, continuing and effective agricultural and livestock programs in particular. Investment in human capital especially in the rural areas leads to more employment opportunities through entrepreneurship and innovation in organic agriculture and livestock production. A holistic approach to developing and improving supply chains could unlock the potential for sophisticated, state-of-the-art organic agriculture and livestock producers and businesses in the region to become EU and global players. Eastern Anatolian livestock producers and the farmers have the ambitions to take part in future progress because the region is naturally organic not by design but default. It is for sure that present potential of the region has not been fully determined and utilized. EU has greatly benefited from previous enlargements economically, politically and socially. When European Union (EU and Turkish Government relations considered and accession of Turkey to EU would be the logical consequence of the previous accessions. The screening on chapter 11

  2. Strengthening the Regional Integration in Central and Eastern Europe through Cohesion Policy Instruments and Cooperation among Stock Exchanges

    Directory of Open Access Journals (Sweden)

    JULIA STEFANOVA

    2014-05-01

    Full Text Available The research paper is focused on the analysis of two ways of strengthening the regional integration in the Central and Eastern Europe – through the Cohesion policy instruments and cooperation among stock exchanges. Substantial benefits from the regional integration through cohesion policy include economic and social prosperity, political understanding. It should be further intensified, as it contributes to reduce regional disparities, exchange knowledge and best practices, ensure economic development. On the other hand, the deepening intra-regional cooperation among CEE stock exchanges leads to quantitative and qualitative changes in the course of their consolidation. Some assumptions are reached regarding expected changes on the Bulgarian capital market in the course of intensifying its intra-regional integrational links to CEE capital markets in conformity with set strategic priorities.

  3. Overview of Iodine Deficiency Prevention Strategies in the South-Eastern Europe and Central Asia Region: 2009–2016

    Directory of Open Access Journals (Sweden)

    Gregory A. Gerasimov

    2018-02-01

    Full Text Available Universal salt iodization (USI strategies gained strong momentum in countries of the Southern Europe and Central Asia (SECA region during the 2000–2009 decade. By the end of the first decade, several countries in the region had already reached the goal of optimum iodine nutrition; other countries were quickly approaching this goal, and in only a few countries the progress toward USI had remained slow. This paper reports an overview of the two Sub-Regional workshops (for countries of Eastern Europe and Central Asia and South-Eastern Europe conducted in 2015 and 2016. Both workshops demonstrate that the SECA region remains on track in the pursuit of USI for sustainable IDD elimination. Notwithstanding the noted imperfections, none of the data or information from countries of the region suggested that the conquest of iodine deficiency is seriously threatened. However, more efforts should be made to develop and streamline USI strategies in Russia and Ukraine, two major countries that are lagging behind.

  4. First definitive record of a stygobiotic fish (Percopsiformes, Amblyopsidae, Typhlichthys from the Appalachians karst region in the eastern United States

    Directory of Open Access Journals (Sweden)

    Matthew L. Niemiller

    2016-11-01

    Full Text Available In the central and eastern United States, cavefishes have been known historically only from the Interior Low Plateau and Ozarks karst regions. Previously, cavefishes were unknown from the Appalachians karst region, which extends from southeastern New York southwestward into eastern Tennessee, northwestern Georgia, and northeastern Alabama. Here we report the discovery of a new population of the amblyopsid cavefish Typhlichthys subterraneus Girard, 1859 from a cave in Catoosa County, Georgia, that significantly extends the known distribution of the species. The cave is located in the Appalachian Valley and Ridge physiographic province and Appalachians karst region, and represents the first definitive report of a stygobiotic fish from the Appalachians karst region. Genetic analyses of one mitochondrial and one nuclear locus from the cavefish indicate this population is closely allied with populations that occur along the western margins of Lookout and Fox mountains in Dade County, Georgia, and populations to the northwest in southern Marion County, Tennessee. It is likely that these populations are also related to those from Wills Valley, DeKalb County, Alabama. The distribution of this new population of T. subterraneus and its close allies pre-dates the emergence of a Tennessee-Coosa River drainage divide in the Pliocene. The potential exists to discover additional populations in caves within the Appalachians karst region in Catoosa County and northward into Hamilton County, Tennessee.

  5. Danger ahead: the burden of diseases, injuries, and risk factors in the Eastern Mediterranean Region, 1990-2015.

    Science.gov (United States)

    2018-05-01

    The Eastern Mediterranean Region faces several health challenges at a difficult time with wars, unrest, and economic change. We used the Global Burden of Disease 2015 study to present the burden of diseases, injuries, and risk factors in the Eastern Mediterranean Region from 1990 to 2015. Ischemic heart disease was the leading cause of death in the region in 2015, followed by cerebrovascular disease. Changes in total deaths ranged from a reduction of 25% for diarrheal diseases to an increase of about 42% for diabetes and tracheal, bronchus, and lung cancer. Collective violence and legal intervention increased by 850% during the time period. Diet was the leading risk factor for disability-adjusted life years (DALYs) for men compared to maternal malnutrition for females. Childhood undernutrition was the leading risk factor for DALYs in 1990 and 2005, but the second in 2015 after high blood pressure. Our study shows that the region is facing several health challenges and calls for global efforts to stabilise the region and to address the current and future burden of disease.

  6. Depression among inmates in a regional prison of eastern Nepal: a cross-sectional study.

    Science.gov (United States)

    Shrestha, Gambhir; Yadav, Deepak Kumar; Sapkota, Nidesh; Baral, Dharanidhar; Yadav, Birendra Kumar; Chakravartty, Avaniendra; Pokharel, Paras Kumar

    2017-10-23

    Depression is the most common form of mental disorder among inmates, with a prevalence much higher than in the general population. This study aims to estimate the prevalence of depression among inmates and identify factors associated with it. This cross-sectional study was conducted in Jhumka Regional Prison, the largest prison in eastern Nepal, from September 2014 to August 2015. A total of 434 randomly selected inmates were interviewed using a semi-structured questionnaire examining socio-demographic characteristics, detention status, self-reported health problems, substance use status, and suicidal ideation. Depression was screened using the Center for Epidemiologic Studies Depression scale. Chi-square tests and multiple logistic regression analysis were applied to determine the association between depression and related variables. The mean age of the participants was 35.7 years (SD 13.3). The prevalence of depression among the inmates was 35.3%. Approximately 2.3% reported suicidal ideation during imprisonment and 0.9% had attempted suicide inside the prison. In bivariate analysis, depression was significantly associated with previous incarceration (OR = 1.91, 95% CI = 1.05-3.47, p = 0.033), poor self-rated health (OR = 1.75, 95% CI = 1.16-2.64, p = 0.007), frequent appointments when encountering health problems (OR = 1.66, 95% CI = 1.06-2.61, p = 0.028), suicidal ideation (OR = 4.44, 95%CI = 1.13-17.44, p = 0.038) and loss of weight (OR = 1.49, 95% CI = 1.00-2.23, p = 0.049). However, only previous incarceration (AOR = 1.97, 95% CI = 1.04-3.74, p = 0.037) and frequent appointments when encountering health problems (AOR = 1.61, 95% CI = 1.01-2.57, p = 0.046) remained significant in a multivariate model. This study showed a high rate of depression among inmates in Nepal. The results suggest a need for psychiatric and rehabilitative care in correctional settings to improve the health status of the inmates.

  7. Baseflow characterization of the inter-mountainous regions of northern Idaho and eastern Washington, USA

    Science.gov (United States)

    Sanchez-Murillo, R.; Brooks, E. S.; Boll, J.; Elliot, W.

    2012-12-01

    Baseflow is one of the most important components of the streamflow regime of any river or creek since it provides continuous habitat to aquatic biota; regulates water temperature and dissolved oxygen during summer; and functions as an essential supply for drinking water and irrigation in most temperate regions. Understanding which factors control how water is released to streams during baseflow periods has become critical for watershed management worldwide, especially, in arid and semiarid areas. This study analyzed storage-discharge relationships of 26 watersheds of northern Idaho and eastern Washington using Brutsaert and Nieber (1977) baseflow recession analysis. Daily streamflow and precipitation records ranged from 7 to 70 years. Mean annual precipitation fluctuated from 536 to 1,312 mm. Drainage basin areas varied from 6.35 to 12,357 km2, with streamgage elevation ranging from 536 to 2,172 m. Mean watershed slope varied from 9.24 to 46.53%. Because of the non-uniqueness watershed shapes, illustrated by the natural spectrum of data points, organic correlation analysis was used to determine the recession coefficients (kb). Numerous climatic attributes and geomorphology characteristics were evaluated as potential predictors of kb rates using a Pearson's correlation matrix. Baseflow coefficients ranged from 0.015 to 0.08 day-1. The mean characteristic timescale for baseflow drainage was found to be 33±15 days with extremes of 12.5 and 66.7 days. Watersheds dominated by basalt features showed the lowest drainage times (12.5-20.0 days). The drainage time increased as the metamorphic and sedimentary rock composition increased (33.3-66.7 days). Watersheds mainly composed by granitic features ranged from 29.1 to 50.0 days. The ratio of mean annual precipitation (MAP) to annual potential evapotranspiration (PET), also known as Aridity Index (AI), was found to explain 67% of kb variability. Mean watershed slope exhibited a moderate negative correlation of -0.57. Other

  8. Project of international science-education center and integration problems of nano science education in far eastern region of Asia

    International Nuclear Information System (INIS)

    Plusnin, N I; Lazarev, G I

    2008-01-01

    Some conception of international science-education center on nano science in Vladivostok is presented. The conception is based on internal and external prerequisites. Internal one is high intellectual potential of institutes of Russian Academy of Sciences and universities of Vladivostok and external one is need of countries of Far Eastern region of Asia in high level manpower. The conception takes into account a specific distribution of science and education potential between Russian Academy of Sciences and Russian universities and a specific their dislocation in Vladivostok. First specific dictates some similarity of organization structure and function of international science-education center to typical science-education center in Russia. But as for dislocation of the international science-education center in Vladivostok, it should be near dislocation of institutes of Far Eastern Brunch of Russian Academy of Sciences in Vladivostok, which are dislocated very compactly in suburb zone of Vladivostok

  9. Ecological study of road traffic injuries in the eastern Mediterranean region: country economic level, road user category and gender perspectives.

    Science.gov (United States)

    Sengoelge, Mathilde; Laflamme, Lucie; El-Khatib, Ziad

    2018-02-13

    The Eastern Mediterranean region has the second highest number of road traffic injury mortality rates after the African region based on 2013 data, with road traffic injuries accounting for 27% of the total injury mortality in the region. Globally the number of road traffic deaths has plateaued despite an increase in motorization, but it is uncertain whether this applies to the Region. This study investigated the regional trends in both road traffic injury mortality and morbidity and examined country-based differences considering on income level, categories of road users, and gender distribution. Register-based ecological study linking data from Global Burden of Disease Study with the United Nations Statistics Division for population and World Bank definition for country income level. Road traffic injury mortality rates and disability-adjusted life years were compiled for all ages at country level in 1995, 2005, 2015 and combined for a regional average (n = 22) and a global average (n = 122). The data were stratified by country economic level, road user category and gender. Road traffic injury mortality rates in the Region were higher than the global average for all three reference years but suggest a downward trend. In 2015 mortality rates were more than twice as high in low and high income countries compared to global income averages and motor vehicle occupants had a 3-fold greater mortality than the global average. Severe injuries decreased by more than half for high/middle income countries but remained high for low income countries; three times higher for males than females. Despite a potential downward trend, inequalities in road traffic injury mortality and morbidity burden remain high in the Eastern Mediterranean region. Action needs to be intensified and targeted to implement and enforce safety measures that prevent and mitigate severe motor vehicle crashes in high income countries especially and invest in efforts to promote public, active transport

  10. Revision of Hydroides Gunnerus, 1768 (Polychaeta: Serpulidae) from the Eastern Pacific region and Hawaii

    NARCIS (Netherlands)

    Bastida-Zavala, J. Rolando; Hove, ten Harry A.

    2003-01-01

    A taxonomic revision of the Hydroides species (Polychaeta: Serpulidae) from the Eastern Pacific Ocean is presented. Twentyone taxa are described, of which two are widespread (H. diramphus Mörch, 1863 and H. elegans (Haswell, 1883)) and four are Amphiamerican (H. alatalateralis (Jones, 1962), H.

  11. Regional climate simulations with COSMO-CLM over MENA-CORDEX domain

    Science.gov (United States)

    Galluccio, Salvatore; Bucchignani, Edoardo; Mercogliano, Paola; Montesarchio, Myriam

    2014-05-01

    In the frame of WCRP Coordinated Regional Downscaling Experiment (CORDEX), a set of common Regional Climate Downscaling (RCD) domains has been defined, as a prerequisite for the development of model evaluation and climate projection frameworks. CORDEX domains encompass the majority of land areas of the world. In this work, climate simulations have been performed over MENA-CORDEX domain, which includes North-Africa, southern Europe and the whole Arabian peninsula. The non-hydrostatic regional climate model COSMO-CLM has been used. At CMCC, regional climate modelling is a part of an integrated simulation system and it has been used in different European and African projects to provide qualitative and quantitative evaluation of the hydrogeological and public health risks. A series of simulations has been conducted over the MENA-CORDEX area at spatial resolution of 0.44°. A sensitivity analysis was conducted to adjust the model configuration to better reproduce the observed climate data. The numerical simulations were driven by ERA-Interim reanalysis (horizontal resolution of 0.703°) for the period 1979-1984; the first year, was considered as a spin up period. The validation was performed by using several data sets: CRU data set was used to validate temperature, precipitation and cloud cover; MERRA data set was used to validate temperature and precipitation and GPCP for precipitation. The model sensitivity to the external parameters was tested considering two different configurations for the surface albedo. In the first one, albedo is only function of soil-type whereas in the second configuration it is prescribed by two external fields for dry and saturated soil based on MODIS data. Moreover, we tested two aerosol distributions as well, namely the default Tanre aerosol distribution and aerosol maps according to Tegen (NASA/GISS). We found, as expected, a significant sensitivity, in particular on the African region. We also varied tuning and physical parameters, such

  12. cDNA cloning of a snake venom metalloproteinase from the eastern diamondback rattlesnake (Crotalus adamanteus), and the expression of its disintegrin domain with anti-platelet effects

    Science.gov (United States)

    Suntravat, Montamas; Jia, Ying; Lucena, Sara E.; Sánchez, Elda E.; Pérez, John C.

    2013-01-01

    A 5′ truncated snake venom metalloproteinase was identified from a cDNA library constructed from venom glands of an eastern diamondback rattlesnake (Crotalus adamanteus). The 5′-rapid amplification of cDNA ends (RACE) was used to obtain the 1865 bp full-length cDNA sequence of a snake venom metalloproteinase (CamVMPII). CamVMPII encodes an open reading frame of 488 amino acids, which includes a signal peptide, a pro-domain, a metalloproteinase domain, a spacer, and an RGD-disintegrin domain. The predicted amino acid sequence of CamVMPII showed a 91%, 90%, 83%, and 82% sequence homology to the P-II class enzymes of C. adamanteus metalloproteinase 2, C. atrox CaVMP-II, Gloydius halys agkistin, and Protobothrops jerdonii jerdonitin, respectively. Disintegrins are potent inhibitors of both platelet aggregation and integrin-dependent cell adhesion. Therefore, the disintegrin domain (Cam-dis) of CamVMPII was amplified by PCR, cloned into a pET-43.1a vector, and expressed in Escherichia coli BL21. Affinity purified recombinantly modified Cam-dis (r-Cam-dis) with a yield of 8.5 mg/L culture medium was cleaved from the fusion tags by enterokinase cleavage. r-Cam-dis was further purified by two-step chromatography consisting of HiTrap™ Benzamidine FF column, followed by Talon Metal affinity column with a final yield of 1 mg/L culture. r-Cam-dis was able to inhibit all three processes of platelet thrombus formation including platelet adhesion with an estimated IC50 of 1 nM, collagen- and ADP-induced platelet aggregation with the estimated IC50s of 18 and 6 nM, respectively, and platelet function on clot retraction. It is a potent anti-platelet inhibitor, which should be further investigated for drug discovery to treat stroke patients or patients with thrombotic disorders. PMID:23313448

  13. A novel heavy domain antibody library with functionally optimized complementarity determining regions.

    Directory of Open Access Journals (Sweden)

    Ole Aalund Mandrup

    Full Text Available Today a number of synthetic antibody libraries of different formats have been created and used for the selection of a large number of recombinant antibodies. One of the determining factors for successful isolation of recombinant antibodies from libraries lies in the quality of the libraries i.e. the number of correctly folded, functional antibodies contained in the library. Here, we describe the construction of a novel, high quality, synthetic single domain antibody library dubbed Predator. The library is based on the HEL4 domain antibody with the addition of recently reported mutations concerning the amino acid composition at positions critical for the folding characteristics and aggregation propensities of domain antibodies. As a unique feature, the CDR3 of the library was designed to mimic the natural human immune response by designating amino acids known to be prevalent in functional antibodies to the diversity in CDR3. CDR randomizations were performed using trinucleotide synthesis to avoid the presence of stop codons. Furthermore a novel cycle free elongation method was used for the conversion of the synthesized single stranded DNA containing the randomized CDRs into double stranded DNA of the library. In addition a modular approach has been adopted for the scaffold in which each CDR region is flanked by unique restrictions sites, allowing easy affinity maturation of selected clones by CDR shuffling. To validate the quality of the library, one round phage display selections were performed on purified antigens and highly complex antigen mixtures such as cultured eukaryotic cells resulting in several specific binders. The further characterization of some of the selected clones, however, indicates a reduction in thermodynamic stability caused by the inclusion the additional mutations to the HEL4 scaffold.

  14. Rock-block characterization on regional to local scales for two SKB sites in Forsmark - Uppland and Laxemar - eastern Smaaland, south-eastern Sweden

    International Nuclear Information System (INIS)

    Beckholmen, Monica; Tiren, Sven A.

    2010-11-01

    Digital elevation data in 500m, 50m and 10m grids were used for rock-block interpretations at regional, semi-regional and local scales of areas around the two SKB sites, Forsmark and Laxemar, objects for the site-investigation programme. Both areas are interpreted to be close to the surface of the sub- Cambrian peneplain and varying altitude and attitude may testify to blockfaulting in the distorted peneplain. Topographic breaks and changes in the gradient also reveal possible zones of weakness that may conduct water. Rock blocks were constructed for Uppland at 1:750 000, northern Uppland at 1:450 000 and the local Forsmark area at 1:150 000, three sets were constructed for eastern Smaaland at 1:500 000, and one for the semi-regional area at 1:250 000 and one for the local Laxemar area at 1:75 000. The orientation of rock-block boundaries and the size of the rock blocks were treated statistically. The rock blocks/polygons were analysed for their mean, minimum and maximum elevation and the range. The values were displayed by maps. The topography in especially eastern Smaaland is dominated by a clear gradient, the land rising from the sea in the east. Efforts were therefore made to remove an estimated gradient to assess the residual features and the same analyses were then made for mean, maximum, minimum and range values. In many cases the results were enhanced and the two types of presentations are complementary to each other. The rock-block interpretations were compared to bedrock and general correlation between major structures where identified. However, the distribution of rocks on a regional map often demonstrates the plastic deformation in a wider zone. Earthquake epicentres were combined with the rock-block maps and assuming that interpreted rock-block boundaries are fairly steep, there is good agreement between the location of epicentres and rock-block boundaries. In some cases it can be seen how seismic disturbance migrated along a structure. Many

  15. Rock-block characterization on regional to local scales for two SKB sites in Forsmark - Uppland and Laxemar - eastern Smaaland, south-eastern Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Beckholmen, Monica; Tiren, Sven A. (GEOSIGMA AB (Sweden))

    2010-11-15

    Digital elevation data in 500m, 50m and 10m grids were used for rock-block interpretations at regional, semi-regional and local scales of areas around the two SKB sites, Forsmark and Laxemar, objects for the site-investigation programme. Both areas are interpreted to be close to the surface of the sub- Cambrian peneplain and varying altitude and attitude may testify to blockfaulting in the distorted peneplain. Topographic breaks and changes in the gradient also reveal possible zones of weakness that may conduct water. Rock blocks were constructed for Uppland at 1:750 000, northern Uppland at 1:450 000 and the local Forsmark area at 1:150 000, three sets were constructed for eastern Smaaland at 1:500 000, and one for the semi-regional area at 1:250 000 and one for the local Laxemar area at 1:75 000. The orientation of rock-block boundaries and the size of the rock blocks were treated statistically. The rock blocks/polygons were analysed for their mean, minimum and maximum elevation and the range. The values were displayed by maps. The topography in especially eastern Smaaland is dominated by a clear gradient, the land rising from the sea in the east. Efforts were therefore made to remove an estimated gradient to assess the residual features and the same analyses were then made for mean, maximum, minimum and range values. In many cases the results were enhanced and the two types of presentations are complementary to each other. The rock-block interpretations were compared to bedrock and general correlation between major structures where identified. However, the distribution of rocks on a regional map often demonstrates the plastic deformation in a wider zone. Earthquake epicentres were combined with the rock-block maps and assuming that interpreted rock-block boundaries are fairly steep, there is good agreement between the location of epicentres and rock-block boundaries. In some cases it can be seen how seismic disturbance migrated along a structure. Many

  16. Pesticides analysed in rainwater in Alsace region (Eastern France): Comparison between urban and rural sites

    Science.gov (United States)

    Scheyer, Anne; Morville, Stéphane; Mirabel, Philippe; Millet, Maurice

    Current-used pesticides commonly applied in Alsace region (Eastern France) on diverse crops (maize, vineyard, vegetables, etc.) were analysed, together with Lindane, in rainwater between January 2002 and June 2003 simultaneously on two sites situated in a typical rural (Erstein, France) and urban area (Strasbourg, France). Rainwater samples were collected on a weekly basis by using two automatic wet only collectors associated with an open collector for the measurement of rainwater height. Pesticides were analysed by GC-MSMS and extracted from rainwater by SPME. Two runs were performed. The first one was performed by using a PDMS (100 μm) fibre for pesticides where direct injection into GC is possible (alachlor, atrazine, azinphos-ethyl, azinphos-methyl, captan, chlorfenvinphos, dichlorvos, diflufenican, α- and β-endosulfan, iprodione, lindane, metolachlor, mevinphos, parathion-methyl, phosalone, phosmet, tebuconazole, triadimefon and trifluralin). The second run was performed by using PDMS/DVB fibre and this run concerns pesticides where a preliminary derivatisation step with pentafluorobenzylbromide (PFBBr) is required for very low volatiles (bromoxynil,2,4-MCPA, MCPP and 2,4-D) or thermo labiles (chlorotoluron, diuron and isoproturon) pesticides. Results showed that the more concentrated pesticides detected were those used as herbicides in large quantities in Alsace region for maize crops (alachlor, metolachlor and atrazine). Maximum concentrations for these herbicides have been measured during intensive applications periods on maize crops following by rapid decrease immediately after use. For Alachlor, most important peaks have been observed between 21 and 28 April 2003 (3327 ng L -1 at Erstein and 5590 ng L -1 at Strasbourg). This is also the case for Metolachlor where most important peak was observed during the same week. Concentrations of pesticides measured out of application periods were very low for many pesticides and some others where never detected

  17. Geothermal development promotion survey report. No. 28. Eastern part of Obanazawa region; 1988-1990 chinetsu kaihatsu sokushin chosa hokokusho. No. 28 Obanazawa tobu chiiki

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1991-03-01

    The results of surveys conducted in the eastern part of Obanazawa region, Yamagata Prefecture, in fiscal 1988-1989 are compiled in this report. Conducted were a geological/alteration zone survey, geochemical survey, electromagnetic surveillance (TDEM - time domain electromagnetic method), gravity prospecting (review of gravity data), electric prospecting (Schlumberger method), heat flow rate survey, test boring, environmental impact survey, and so forth. Conclusions are mentioned below. It is inferred that the water of the Ginzan hot spring of the neutral Cl-SO{sub 4} type originates in meteoric water in mountains high above the mean sea level in the western side and that the hot spring water is produced when water heated to approximately 170 degrees C at a depth (1,500-2,000 meters below mean sea level) in the Ginzan hot spring district, where the ground temperature is the highest in this region, is diluted by groundwater near the surface at its ultimate stage of ascent. The survey results disclose that possibilities are quite low that a high-temperature sector of 200 degrees C or higher is found at a level not deeper than 2,000 meters from the ground surface. Accordingly, no geothermal development by flash steam power generation is feasible at the present stage at any economically acceptable depth. (NEDO)

  18. HIV Viral Load Trends in Six Eastern Caribbean Countries Utilizing a Regional Laboratory Referral Service: Implications for Treatment as Prevention.

    Science.gov (United States)

    Landis, R Clive; Carmichael-Simmons, Kelly; Hambleton, Ian R; Best, Anton

    2015-01-01

    Since 2009, seven countries in the Organization of Eastern Caribbean States (OECS), Antigua & Barbuda, Dominica, Grenada, Montserrat, St. Kitts & Nevis, Saint Lucia, and St. Vincent & the Grenadines, have been utilizing a laboratory referral service for HIV-1 viral load (VL) offered by The Ladymeade Reference Unit (LRU) Laboratory, Barbados. The objective of this study was to evaluate 5 year VL trends in the six larger OECS countries participating in this regional referral service. Blood samples were collected in source countries and transported to Barbados as frozen plasma according to a standardized protocol. Plasma specimens were amplified by RT PCR on a Roche TaqMan 48 analyser (Roche Diagnostics, Panama City, Panama). VL was considered optimally suppressed below a threshold level of < 200 HIV-1 copies/mL of blood. The same threshold was used as a binary indicator in an analysis of the secular change in VL suppression. Montserrat was excluded due to insufficient number of samples. A steady rise in VL referrals from OECS countries was recorded, rising from 312 samples in 2009 to 1,060 samples in 2013. A total of 3,543 samples were tested, with a sample rejection rate (9.2%) mostly due to breaks in the cold chain. Aggregate VL data showed the odds of VL suppression in the Eastern Caribbean improved by 66% for each additional year after 2009 (Odds Ratio 1.66 [95% CI 1.46 to 1.88]; p<0.001). We demonstrate the feasibility of establishing a regional laboratory referral service for HIV VL monitoring in the Eastern Caribbean. Aggregate VL trends showed a significant year-on-year improvement in VL suppression, implying public health benefits through treatment as prevention in the OECS. VL provides a powerful monitoring & evaluation tool for strengthening HIV programs at country level among the small island states participating in this regional referral network.

  19. HIV Viral Load Trends in Six Eastern Caribbean Countries Utilizing a Regional Laboratory Referral Service: Implications for Treatment as Prevention.

    Directory of Open Access Journals (Sweden)

    R Clive Landis

    Full Text Available Since 2009, seven countries in the Organization of Eastern Caribbean States (OECS, Antigua & Barbuda, Dominica, Grenada, Montserrat, St. Kitts & Nevis, Saint Lucia, and St. Vincent & the Grenadines, have been utilizing a laboratory referral service for HIV-1 viral load (VL offered by The Ladymeade Reference Unit (LRU Laboratory, Barbados. The objective of this study was to evaluate 5 year VL trends in the six larger OECS countries participating in this regional referral service.Blood samples were collected in source countries and transported to Barbados as frozen plasma according to a standardized protocol. Plasma specimens were amplified by RT PCR on a Roche TaqMan 48 analyser (Roche Diagnostics, Panama City, Panama. VL was considered optimally suppressed below a threshold level of < 200 HIV-1 copies/mL of blood. The same threshold was used as a binary indicator in an analysis of the secular change in VL suppression. Montserrat was excluded due to insufficient number of samples.A steady rise in VL referrals from OECS countries was recorded, rising from 312 samples in 2009 to 1,060 samples in 2013. A total of 3,543 samples were tested, with a sample rejection rate (9.2% mostly due to breaks in the cold chain. Aggregate VL data showed the odds of VL suppression in the Eastern Caribbean improved by 66% for each additional year after 2009 (Odds Ratio 1.66 [95% CI 1.46 to 1.88]; p<0.001.We demonstrate the feasibility of establishing a regional laboratory referral service for HIV VL monitoring in the Eastern Caribbean. Aggregate VL trends showed a significant year-on-year improvement in VL suppression, implying public health benefits through treatment as prevention in the OECS. VL provides a powerful monitoring & evaluation tool for strengthening HIV programs at country level among the small island states participating in this regional referral network.

  20. Molecular dissection of the interaction between the SH3 domain and the SH2-Kinase Linker region in PTK6.

    Science.gov (United States)

    Kim, Han Ie; Jung, Jinwon; Lee, Eun-Saem; Kim, Yong-Chul; Lee, Weontae; Lee, Seung-Taek

    2007-11-03

    PTK6 (also known as Brk) is an intracellular tyrosine kinase that contains SH3, SH2, and tyrosine kinase catalytic (Kinase) domains. The SH3 domain of PTK6 interacts with the N-terminal half of the linker (Linker) region between the SH2 and Kinase domains. Site-directed mutagenesis and surface plasmon resonance studies showed that a tryptophan residue (Trp44) in the SH3 domain and proline residues in the Linker region, in the order of Pro177, Pro175, and Pro179, contribute to the interaction. The three-dimensional modeled structure of the SH3-Linker complex was in agreement with the biochemical data. Disruption of the intramolecular interaction between the SH3 domain and the Linker region by mutation of Trp44, Pro175, Pro177, and Pro179 markedly increased the catalytic activity of PTK6 in HEK 293 cells. These results demonstrate that Trp44 in the SH3 domain and Pro177, Pro175, and Pro179 in the N-terminal half of the Linker region play important roles in the SH3-Linker interaction to maintain the protein in an inactive conformation along with the phosphorylated Tyr447-SH2 interaction.

  1. Bio- and toxic elements in edible wild mushrooms from two regions of potentially different environmental conditions in eastern Poland.

    Science.gov (United States)

    Brzezicha-Cirocka, Justyna; Mędyk, Małgorzata; Falandysz, Jerzy; Szefer, Piotr

    2016-11-01

    In the present study, the composition of bio-elements (K, Na, Mg, Ca, Fe, Cu, Zn) and toxic elements (Ag, Cd) in seven edible mushrooms from the rural and woodland region of Morąg (north-eastern Poland) and the rural and industrial region of the Tarnobrzeska Upland (south-eastern Poland) were investigated using a validated method. The species examined were Boletus edulis, Cantharellus cibarius, Leccinum aurantiacum, Leccinum versipelle, Lycoperdon perlatum, Suillus luteus, and Xerocomus subtomentosus. Final determination was carried out by flame atomic absorption spectroscopy (FAAS) after microwave-assisted decomposition of sample matrices with solutions of concentrated nitric acid in the pressurized polytetrafluoroethylene vessels. The contents of the alkali elements and alkali earth elements were determined in the species surveyed. The alkali elements, earth alkali elements, and transition metals (Ag, Cu, Zn, Fe, and Mn) were at typical concentrations as was determined for the same or similar species elsewhere in Poland and Europe. The results may suggest a lack of local and regional emissions of those metallic elements from industrialization of some sites in the Tarnobrzeska Plain. Cadmium was at elevated concentrations in L. versipelle from the Tarnobrzeska Plain but the reason-pollution or geogenic source-was unknown, while it was at typical concentrations in other species.

  2. Establishment of the South-Eastern Norway Regional Health Authority Resource Center for Children with Prenatal Alcohol/Drug Exposure

    Directory of Open Access Journals (Sweden)

    Gro C. C. Løhaugen

    2015-01-01

    Full Text Available This paper presents a new initiative in the South-Eastern Health Region of Norway to establish a regional resource center focusing on services for children and adolescents aged 2–18 years with prenatal exposure to alcohol or other drugs. In Norway, the prevalence of fetal alcohol spectrum (FAS is not known but has been estimated to be between 1 and 2 children per 1000 births, while the prevalence of prenatal exposure to illicit drugs is unknown. The resource center is the first of its kind in Scandinavia and will have three main objectives: (1 provide hospital staff, community health and child welfare personnel, and special educators with information, educational courses, and seminars focused on the identification, diagnosis, and treatment of children with a history of prenatal alcohol/drug exposure; (2 provide specialized health services, such as diagnostic services and intervention planning, for children referred from hospitals in the South-Eastern Health Region of Norway; and (3 initiate multicenter studies focusing on the diagnostic process and evaluation of interventions.

  3. Natural radioactivity in some drinking water sources of coastal, northern, eastern and AlJazera regions in Syria

    International Nuclear Information System (INIS)

    Al-Masri, M. S.; Byrakdar, E.; Amin, Y.; Abu Baker, S.

    2003-01-01

    Naturally occurring radionuclides in drinking water sources of coastal, northern, eastern and AlJazera regions in Syria have been determined. Samples were collected during the year of 2000 at two periods from the main water sources, from which water being transported for drinking or from houses. Results have shown that most concentrations of the measured naturally occurring radionuclides ( 222 Rn, 222 Ra, 210 Po, 234 U, 238 U) were within the natural levels and below the higher permissible limits of International Organizations. In addition, variations in concentrations from region to another have been observed; these variations may be due to differences in geological formations and water sources (well, spring, surface water). Moreover, the obtained data in this study and other published data for other regions can be used for establishing the radiation map for natural radioactivity in drinking water in Syria. (author)

  4. Molecular Dynamics Simulations of the STAS Domains of Rat Prestin and Human Pendrin Reveal Conformational Motions in Conserved Flexible Regions

    Directory of Open Access Journals (Sweden)

    Alok K. Sharma

    2014-02-01

    Full Text Available Background: Molecular dynamics (MD simulations provide valuable information on the conformational changes that accompany time-dependent motions in proteins. The reported crystal structure of rat prestin (PDB 3LLO is remarkable for an α1-α2 inter-helical angle that differs substantially from those observed in bacterial STAS domains of SulP anion transporters and anti-sigma factor antagonists. However, NMR data on the rat prestin STAS domain in solution suggests dynamic features at or near the α1-α2 helical region (Pasqualetto et al JMB, 2010. We therefore performed a 100 ns 300K MD simulation study comparing the STAS domains of rat prestin and (modeled human pendrin, to explore possible conformational flexibility in the region of the α1 and α2 helices. Methods: The conformation of the loop missing in the crystal structure of rat prestin STAS (11 amino acids between helix α1 and strand β3 was built using Modeller. MD simulations were performed with GROMACSv4.6 using GROMOS96 53a6 all-atom force field. Results: A subset of secondary structured elements of the STAS domains exhibits significant conformational changes during the simulation time course. The conformationally perturbed segments include the majority of loop regions, as well as the α1 and α2 helices. A significant decrease in the α1-α2 inter-helical angle observed across the simulation trajectory leads to closer helical packing at their C-termini. The end-simulation conformations of the prestin and pendrin STAS domains, including their decreased α1-α2 inter-helical angles, resemble more closely the packing of corresponding helices in the STAS structures of bacterial SulP transporters Rv1739c and ychM, as well as those of the anti-sigma factor antagonists. Several structural segments of the modeled human pendrin STAS domain exhibit larger atomic motions and greater conformational deviations than the corresponding regions of rat prestin, predicting that the human pendrin STAS

  5. Effective crop evapotranspiration measurement using time-domain reflectometry technique in a sub-humid region

    Science.gov (United States)

    Srivastava, R. K.; Panda, R. K.; Halder, Debjani

    2017-08-01

    The primary objective of this study was to evaluate the performance of the time-domain reflectometry (TDR) technique for daily evapotranspiration estimation of peanut and maize crop in a sub-humid region. Four independent methods were used to estimate crop evapotranspiration (ETc), namely, soil water balance budgeting approach, energy balance approach—(Bowen ratio), empirical methods approach, and Pan evaporation method. The soil water balance budgeting approach utilized the soil moisture measurement by gravimetric and TDR method. The empirical evapotranspiration methods such as combination approach (FAO-56 Penman-Monteith and Penman), temperature-based approach (Hargreaves-Samani), and radiation-based approach (Priestley-Taylor, Turc, Abetw) were used to estimate the reference evapotranspiration (ET0). The daily ETc determined by the FAO-56 Penman-Monteith, Priestley-Taylor, Turc, Pan evaporation, and Bowen ratio were found to be at par with the ET values derived from the soil water balance budget; while the methods Abetw, Penman, and Hargreaves-Samani were not found to be ideal for the determination of ETc. The study illustrates the in situ applicability of the TDR method in order to make it possible for a user to choose the best way for the optimum water consumption for a given crop in a sub-humid region. The study suggests that the FAO-56 Penman-Monteith, Turc, and Priestley-Taylor can be used for the determination of crop ETc using TDR in comparison to soil water balance budget.

  6. Sensitivity analysis with the regional climate model COSMO-CLM over the CORDEX-MENA domain

    Science.gov (United States)

    Bucchignani, E.; Cattaneo, L.; Panitz, H.-J.; Mercogliano, P.

    2016-02-01

    The results of a sensitivity work based on ERA-Interim driven COSMO-CLM simulations over the Middle East-North Africa (CORDEX-MENA) domain are presented. All simulations were performed at 0.44° spatial resolution. The purpose of this study was to ascertain model performances with respect to changes in physical and tuning parameters which are mainly related to surface, convection, radiation and cloud parameterizations. Evaluation was performed for the whole CORDEX-MENA region and six sub-regions, comparing a set of 26 COSMO-CLM runs against a combination of available ground observations, satellite products and reanalysis data to assess temperature, precipitation, cloud cover and mean sea level pressure. The model proved to be very sensitive to changes in physical parameters. The optimized configuration allows COSMO-CLM to improve the simulated main climate features of this area. Its main characteristics consist in the new parameterization of albedo, based on Moderate Resolution Imaging Spectroradiometer data, and the new parameterization of aerosol, based on NASA-GISS AOD distributions. When applying this configuration, Mean Absolute Error values for the considered variables are as follows: about 1.2 °C for temperature, about 15 mm/month for precipitation, about 9 % for total cloud cover, and about 0.6 hPa for mean sea level pressure.

  7. Petrography, geochemistry and Sm-Nd isotopes of the granites from eastern of the Tapajós Domain, Pará state

    Directory of Open Access Journals (Sweden)

    Flávio Robson Dias Semblano

    Full Text Available ABSTRACT: The Tapajós Domain, located in the southern portion of the Amazonian Craton, is a tectonic domain of the Tapajós-Parima Province, a Paleoproterozoic orogenic belt adjacent to a reworked Archean crust, the Central Amazonian Province. This domain has been interpreted as the product of an assemblage of successive magmatic arcs followed by post-orogenic A-type magmatism formed ca. 1880 Ma-old granites of the Maloquinha Intrusive Suite. The study presented here was carried out in four granitic bodies of this suite (Igarapé Tabuleiro, Dalpaiz, Mamoal and Serra Alta from the eastern part of the Tapajós Domain, as well as an I-type granite (Igarapé Salustiano related to the Parauari Intrusive Suite. The A-type granites are syenogranites and monzogranites, and alkali feldspar granites and quartz syenites occur subordinately. These rocks are ferroan, alkalic-calcic to alkalic and dominantly peraluminous, with negative anomalies of Ba, Sr, P and Ti and high rare earth elements (REE contents with pronounced negative Eu anomaly. This set of features is typical of A-type granites. The Igarapé Salustiano granite encompasses monzogranites and quartz monzonites, which are magnesian, calcic to calc-alkalic, high-K and mainly metaluminous, with high Ba and Sr contents and depleted pattern in high field strength elements (HFSE and heavy rare earth elements (HREE, characteristic of I-type granites. The source of magma of these A-type granites is similar to post-collisional granites, while the I-type granite keeps syn-collisional signature. Most of the studied granites have εNd (-3.85 to -0.76 and Nd TDM model ages (2.22 to 2.46 Ga compatible with the Paleoproterozoic crust of the Tapajós Domain. We conclude that the Archean crust source (εNd of -5.01 and Nd TDM of 2.6 Ga was local for these A-type granites.

  8. Functional analysis of the NH{sub 2}-terminal hydrophobic region and BRICHOS domain of GKN1

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Jung Hwan; Choi, Yoo Jin; Choi, Won Suk; Nam, Suk Woo; Lee, Jung Young; Park, Won Sang, E-mail: wonsang@catholic.ac.kr

    2013-11-01

    Highlights: •NH{sub 2}-terminal and BRICHOS domain of GKN1 inhibited tumor cell growth. •NH{sub 2}-terminal and BRICHOS domain of GKN1 regulated cell cycle. •NH{sub 2}-terminal and BRICHOS domain of GKN1 inhibited epigenetic regulators. -- Abstract: Gastrokine 1 (GKN1) protects the gastric antral mucosa and promotes healing by facilitating restitution and proliferation after injury. GKN1 is down-regulated in Helicobacter pylori-infected gastric epithelial cells and loss of GKN1 expression is tightly associated with gastric carcinogenesis. However, the underlying mechanisms as a tumor suppressor are largely unknown. Presently, the hydrophobic region and BRICHOS domain of GKN1, pGKN1{sup D13N}, pGKN1{sup Δ68–199}, and pGKN1{sup Δ1–67,165–199} were shown to suppress gastric cancer cell growth and recapitulate GKN1 functions. As well, the hydrophobic region and BRICHOS domain of GKN1 had a synergistic anti-cancer effect with 5-FU on tumor cell growth, implying that the NH{sub 2}-terminal hydrophobic region and BRICHOS domain of GKN1 are sufficient for tumor suppression, thereby suggesting a therapeutic intervention for gastric cancer. Also, its domain inducing endogenous miR-185 directly targeted the epigenetic effectors DNMT1 and EZH2 in gastric cancer cells. Our results suggest that the NH{sub 2}-terminal hydrophobic region and BRICHOS domain of GKN1 are sufficient for its tumor suppressor activities.

  9. Distributed HUC-based modeling with SUMMA for ensemble streamflow forecasting over large regional domains.

    Science.gov (United States)

    Saharia, M.; Wood, A.; Clark, M. P.; Bennett, A.; Nijssen, B.; Clark, E.; Newman, A. J.

    2017-12-01

    Most operational streamflow forecasting systems rely on a forecaster-in-the-loop approach in which some parts of the forecast workflow require an experienced human forecaster. But this approach faces challenges surrounding process reproducibility, hindcasting capability, and extension to large domains. The operational hydrologic community is increasingly moving towards `over-the-loop' (completely automated) large-domain simulations yet recent developments indicate a widespread lack of community knowledge about the strengths and weaknesses of such systems for forecasting. A realistic representation of land surface hydrologic processes is a critical element for improving forecasts, but often comes at the substantial cost of forecast system agility and efficiency. While popular grid-based models support the distributed representation of land surface processes, intermediate-scale Hydrologic Unit Code (HUC)-based modeling could provide a more efficient and process-aligned spatial discretization, reducing the need for tradeoffs between model complexity and critical forecasting requirements such as ensemble methods and comprehensive model calibration. The National Center for Atmospheric Research is collaborating with the University of Washington, the Bureau of Reclamation and the USACE to implement, assess, and demonstrate real-time, over-the-loop distributed streamflow forecasting for several large western US river basins and regions. In this presentation, we present early results from short to medium range hydrologic and streamflow forecasts for the Pacific Northwest (PNW). We employ a real-time 1/16th degree daily ensemble model forcings as well as downscaled Global Ensemble Forecasting System (GEFS) meteorological forecasts. These datasets drive an intermediate-scale configuration of the Structure for Unifying Multiple Modeling Alternatives (SUMMA) model, which represents the PNW using over 11,700 HUCs. The system produces not only streamflow forecasts (using the Mizu

  10. Physical Environmental Correlates of Domain-Specific Sedentary Behaviours across Five European Regions (the SPOTLIGHT Project).

    Science.gov (United States)

    Compernolle, Sofie; De Cocker, Katrien; Roda, Célina; Oppert, Jean-Michel; Mackenbach, Joreintje D; Lakerveld, Jeroen; Glonti, Ketevan; Bardos, Helga; Rutter, Harry; Cardon, Greet; De Bourdeaudhuij, Ilse

    2016-01-01

    The relation between neighbourhood environmental factors and domain-specific sedentary behaviours among adults remains unclear. This study firstly aims to examine the association of perceived and objectively measured neighbourhood safety, aesthetics, destinations and functionality with transport-related, work-related and leisure-time sedentary behaviour. Secondly, the study aims to assess whether these associations are moderated by age, gender or educational level. In 60 randomly sampled neighbourhoods from 5 urban regions in Europe (Ghent and suburbs, Paris and inner suburbs, Budapest and suburbs, the Randstad, and Greater London), a virtual audit with Google Street View was performed to assess environmental characteristics. A total of 5,205 adult inhabitants of these neighbourhoods reported socio-demographic characteristics, sedentary behaviours, and neighbourhood perceptions in an online survey. Generalized linear mixed models were conducted to examine associations between physical environmental neighbourhood factors and sedentary behaviours. Interaction terms were added to test the moderating role of individual-level socio-demographic variables. Lower levels of leisure-time sedentary behaviour (i.e. all leisure activities except television viewing and computer use) were observed among adults who perceived greater numbers of destinations such as supermarkets, recreational facilities, or restaurants in their neighbourhood, and among adults who lived in a neighbourhood with more objectively measured aesthetic features, such as trees, water areas or public parks. Lower levels of work-related sedentary behaviour were observed among adults who perceived less aesthetic features in their neighbourhood, and among adults who lived in a neighbourhood with less objectively measured destinations. Both age, gender and educational level moderated the associations between neighbourhood environmental factors and sedentary behaviours. Preliminary evidence was found for

  11. Physical Environmental Correlates of Domain-Specific Sedentary Behaviours across Five European Regions (the SPOTLIGHT Project.

    Directory of Open Access Journals (Sweden)

    Sofie Compernolle

    Full Text Available The relation between neighbourhood environmental factors and domain-specific sedentary behaviours among adults remains unclear. This study firstly aims to examine the association of perceived and objectively measured neighbourhood safety, aesthetics, destinations and functionality with transport-related, work-related and leisure-time sedentary behaviour. Secondly, the study aims to assess whether these associations are moderated by age, gender or educational level.In 60 randomly sampled neighbourhoods from 5 urban regions in Europe (Ghent and suburbs, Paris and inner suburbs, Budapest and suburbs, the Randstad, and Greater London, a virtual audit with Google Street View was performed to assess environmental characteristics. A total of 5,205 adult inhabitants of these neighbourhoods reported socio-demographic characteristics, sedentary behaviours, and neighbourhood perceptions in an online survey. Generalized linear mixed models were conducted to examine associations between physical environmental neighbourhood factors and sedentary behaviours. Interaction terms were added to test the moderating role of individual-level socio-demographic variables.Lower levels of leisure-time sedentary behaviour (i.e. all leisure activities except television viewing and computer use were observed among adults who perceived greater numbers of destinations such as supermarkets, recreational facilities, or restaurants in their neighbourhood, and among adults who lived in a neighbourhood with more objectively measured aesthetic features, such as trees, water areas or public parks. Lower levels of work-related sedentary behaviour were observed among adults who perceived less aesthetic features in their neighbourhood, and among adults who lived in a neighbourhood with less objectively measured destinations. Both age, gender and educational level moderated the associations between neighbourhood environmental factors and sedentary behaviours.Preliminary evidence was

  12. Prostate segmentation by feature enhancement using domain knowledge and adaptive region based operations

    International Nuclear Information System (INIS)

    Nanayakkara, Nuwan D; Samarabandu, Jagath; Fenster, Aaron

    2006-01-01

    Estimation of prostate location and volume is essential in determining a dose plan for ultrasound-guided brachytherapy, a common prostate cancer treatment. However, manual segmentation is difficult, time consuming and prone to variability. In this paper, we present a semi-automatic discrete dynamic contour (DDC) model based image segmentation algorithm, which effectively combines a multi-resolution model refinement procedure together with the domain knowledge of the image class. The segmentation begins on a low-resolution image by defining a closed DDC model by the user. This contour model is then deformed progressively towards higher resolution images. We use a combination of a domain knowledge based fuzzy inference system (FIS) and a set of adaptive region based operators to enhance the edges of interest and to govern the model refinement using a DDC model. The automatic vertex relocation process, embedded into the algorithm, relocates deviated contour points back onto the actual prostate boundary, eliminating the need of user interaction after initialization. The accuracy of the prostate boundary produced by the proposed algorithm was evaluated by comparing it with a manually outlined contour by an expert observer. We used this algorithm to segment the prostate boundary in 114 2D transrectal ultrasound (TRUS) images of six patients scheduled for brachytherapy. The mean distance between the contours produced by the proposed algorithm and the manual outlines was 2.70 ± 0.51 pixels (0.54 ± 0.10 mm). We also showed that the algorithm is insensitive to variations of the initial model and parameter values, thus increasing the accuracy and reproducibility of the resulting boundaries in the presence of noise and artefacts

  13. Constraints on the Miocene landscape evolution of the Eastern Alps from the Kalkspitze region, Niedere Tauern (Austria)

    Science.gov (United States)

    Dertnig, Florian; Stüwe, Kurt; Woodhead, Jon; Stuart, Finlay M.; Spötl, Christoph

    2017-12-01

    In order to unravel aspects of the Miocene landscape evolution of the eastern European Alps, we present geomorphic and isotopic data from the western Niedere Tauern region (Austria). The region is critical for such interpretations, because it is one of the few regions along the topographic axis of the Eastern Alps where the highest peaks (up to 2500 m a.s.l.) are dominated by limestone. As such, the region contains a record of Miocene landscape-forming events that survived the Pleistocene glaciations, not preserved elsewhere in the central Eastern Alps. This record includes karst caves, karstified planation surfaces and crystalline fluvial pebbles (Augenstein Formation) preserved on planation surfaces and in karst caves. Caves in the region occur in three distinct levels that correlate with well-known cave levels in the Northern Calcareous Alps, although they are somewhat higher in the Niedere Tauern. In part, these cave elevations also correlate with three planation surfaces and knickpoints of major streams draining the region, testifying their pre-glacial origin. We report details of a karst cave (Durchgangshöhle) from the highest cave level located at 2340 m a.s.l. In this cave, allochthonous fluvial gravels are present, overgrown by speleothems. One speleothem yielded an early middle Pleistocene U-Pb age (682 ± 17 ka). We regard this as a minimum age for the erosion of the fluvial cave deposits during Marine Isotope Stages 17 or 16. Carbon and oxygen isotope data of these speleothems imply a climate that is consistent with this interpretation. Cosmogenic 21Ne data of fluvial quartz clasts collected from the surface on plateaus of the Northern Calcareous Alps suggest minimum exposure durations of 115 and 262 ka. They probably reflect successive exposure since removal of the sediment cover of the Oligocene Augenstein Formation during the Pleistocene. While our geochronological data fail to record aspects of the earlier Miocene uplift history, they are

  14. Irradiation of ready-to-eat foods at USDA'S Eastern Regional Reasearch Center - 2003 update

    Energy Technology Data Exchange (ETDEWEB)

    Sommers, Christopher; Fan Xuetong; Niemira, Brendan; Rajkowski, Kathleen

    2004-10-01

    Ionizing radiation is a safe and effective method for eliminating bacterial pathogens from food products and disinfestation of fruits and vegetables. Since 1980 research has been conducted at USDA's Eastern Regional Research Center pertaining to the elimination of food-borne pathogens from meat, poultry, fruit and vegetable products. Recent work has focused on elimination of pathogens such as Escherichia coli O157:H7, Salmonella spp., and Listeria monocytogenes from ready-to-eat (RTE) food products including hot dogs, bologna, lettuce, cilantro, sprouts and seeds, and frozen vegetables. The ionizing radiation dose required to eliminate those pathogens from RTE foods has been found to be commodity, formulation and temperature dependent. The need to eliminate bacterial pathogens from RTE food products must always be balanced with the maintenance of product quality. In addition to determining the effective ionizing radiation doses required for pathogen elimination the effects of irradiation on product chemistry, nutritional value and organoleptic quality have also been determined. A review of the studies conducted at USDA's Eastern Regional Research Center in 2002 and 2003 is presented in this article.

  15. Post-Ocular Trauma Corneal Staphyloma in a Child Living in an Underdeveloped Region of Eastern Indonesia

    Science.gov (United States)

    Sitompul, Ratna; Kusumowidagdo, Gladys; Matiur, Eiko B.; Barliana, Julie D.; Sitorus, Rita S.; Sungkar, Saleha

    2018-01-01

    Ocular trauma occurring in children often leads to visual impairment or blindness when it is not properly managed. This often occurs in underdeveloped regions with difficult access to professional care at local health facilities. We report a case of post-trauma corneal staphyloma in an underdeveloped region of eastern Indonesia to illustrate the importance of proper management of ocular trauma in areas lacking such expertise and where patients have difficulty accessing even basic health care. During a community health outreach in Southwest Sumba, eastern Indonesia in May 2017, a 7-year-old boy presented with white protrusion of the left eye of 3 years' duration following an event of sharp trauma. The patient lived in an inaccessible and impoverished area. Upon contemporary examination, visual acuity of the left eye was 1/300 while that of the right eye was 6/6. Anterior examination revealed corneal staphyloma of the left eye, and its posterior segment could not be evaluated. The patient was transported to an eye care center in Jakarta, receiving a stock prosthesis implant while awaiting a corneal evisceration procedure with dermofat graft. Ocular trauma is one of the most common causes of visual impairment in children. This case illustrates the consequences of inadequate post-trauma management and the importance of prevention of infection. PMID:29681830

  16. Examination of Relationships among Organizational Characteristics and Organizational Commitment of Nurses in Western and Eastern Region of Nepal.

    Science.gov (United States)

    Joshi, A S; Namba, M; Pokharela, T

    2015-01-01

    The objective of this study is to identify relationships between three components of organizational commitment and organizational characteristics of nurses in the western and the eastern region of Nepal. A self-administrated questionnaire was used to collect data from 310 nurses currently working at various hospitals in the eastern and the western region of the country. The questionnaire included three sections namely 1) personal characteristics 2) organizational characteristics and 3) organizational commitments scale. Descriptive analysis and multiple regression analysis were performed to identify significance in various relationships. Out of the 240 completed questionnaires, 226 were found valid for analysis. The mean age was 27.4 years. For each depended variable affective, continuance and normative commitment, multiple regression analysis was performed with personal Characteristics and organizational characteristics as independent variables. All independent variables were found significantly related to each of the two dependent variables; affective commitment and normative commitment (R2 adjusted=0.24, pcommitment. Both support from boss (β=0.138, pcommitment. On the other hand, satisfaction with training (β=0.191, pcommitment. Since both support from boss and training program were found to be positive and significant with affective commitment, hospitals must encourage supervisors to provide more assistance to the subordinate nurses. Moreover, hospitals should develop more training programs to keep nurses motivated.

  17. Post-Ocular Trauma Corneal Staphyloma in a Child Living in an Underdeveloped Region of Eastern Indonesia

    Directory of Open Access Journals (Sweden)

    Ratna Sitompul

    2018-02-01

    Full Text Available Ocular trauma occurring in children often leads to visual impairment or blindness when it is not properly managed. This often occurs in underdeveloped regions with difficult access to professional care at local health facilities. We report a case of post-trauma corneal staphyloma in an underdeveloped region of eastern Indonesia to illustrate the importance of proper management of ocular trauma in areas lacking such expertise and where patients have difficulty accessing even basic health care. During a community health outreach in Southwest Sumba, eastern Indonesia in May 2017, a 7-year-old boy presented with white protrusion of the left eye of 3 years’ duration following an event of sharp trauma. The patient lived in an inaccessible and impoverished area. Upon contemporary examination, visual acuity of the left eye was 1/300 while that of the right eye was 6/6. Anterior examination revealed corneal staphyloma of the left eye, and its posterior segment could not be evaluated. The patient was transported to an eye care center in Jakarta, receiving a stock prosthesis implant while awaiting a corneal evisceration procedure with dermofat graft. Ocular trauma is one of the most common causes of visual impairment in children. This case illustrates the consequences of inadequate post-trauma management and the importance of prevention of infection.

  18. Epidemiological aspects of prematurity in the Eastern region of Saudi Arabia

    Directory of Open Access Journals (Sweden)

    Faisal O. Al-Qurashi

    2016-04-01

    Full Text Available Objectives: To assess the epidemiological characteristics of prematurity and survival rate in preterm infants diagnosed at a university hospital in the Eastern province of Saudi Arabia. Methods: A retrospective study was carried out of 476 preterm infants who were admitted with the diagnosis of prematurity to King Fahd Hospital of the University, Al-Khobar, Saudi Arabia, between June 2008 and 2013. Demographics, birth weight, and neonatal survival rate were analyzed. Results: Four hundred and seventy-six preterm infants were admitted with a total prevalence of 7.5%. Descriptive analysis revealed 55% were males. Extremely preterm infants (<28 weeks’ gestation comprised 9% and very preterm infants (28 to <32 weeks’ gestation comprised 20%. Extremely low-birth-weight (ELBW infants (<1000 g comprised 11%. One hundred and fifty-seven (32% infants were small for gestational age. Out of the total number of ELBW infants, 58% of them were discharged. The overall mortality was 7.6%. The mortality rate of male infants was 53%. The survival to discharge according to gestational age ranged from 30-97.6%. Conclusion: The estimated prevalence of preterm births in a university hospital in eastern province of Saudi Arabia, is consistent with various studies from different parts of the world.

  19. Investigation of the climate-driven periodicity of shallow groundwater level fluctuations in a Central-Eastern European agricultural region

    Science.gov (United States)

    Garamhegyi, Tamás; Kovács, József; Pongrácz, Rita; Tanos, Péter; Hatvani, István Gábor

    2018-05-01

    The distribution and amount of groundwater, a crucial source of Earth's drinking and irrigation water, is changing due to climate-change effects. Therefore, it is important to understand groundwater behavior in extreme scenarios, e.g. drought. Shallow groundwater (SGW) level fluctuation under natural conditions displays periodic behavior, i.e. seasonal variation. Thus, the study aims to investigate (1) the periodic behavior of the SGW level time series of an agriculturally important and drought-sensitive region in Central-Eastern Europe - the Carpathian Basin, in the north-eastern part of the Great Hungarian Plain, and (2) its relationship to the European atmospheric pressure action centers. Data from 216 SGW wells were studied using wavelet spectrum analysis and wavelet coherence analyses for 1961-2010. Locally, a clear relationship exists between the absence of annual periodic behavior in the SGW level and the periodicity of droughts, as indicated by the self-calibrating Palmer Drought Severity Index and the Aridity Index. During the non-periodic intervals, significant drops in groundwater levels (average 0.5 m) were recorded in 89% of the wells. This result links the meteorological variables to the periodic behavior of SGW, and consequently, drought. On a regional scale, Mediterranean cyclones from the Gulf of Genoa (northwest Italy) were found to be a driving factor in the 8-yr periodic behavior of the SGW wells. The research documents an important link between SGW levels and local/regional climate variables or indices, thereby facilitating the necessary adaptation strategies on national and/or regional scales, as these must take into account the predictions of drought-related climatic conditions.

  20. The Receptor-Binding Domain in the VP1u Region of Parvovirus B19.

    Science.gov (United States)

    Leisi, Remo; Di Tommaso, Chiarina; Kempf, Christoph; Ros, Carlos

    2016-02-24

    Parvovirus B19 (B19V) is known as the human pathogen causing the mild childhood disease erythema infectiosum. B19V shows an extraordinary narrow tissue tropism for erythroid progenitor cells in the bone marrow, which is determined by a highly restricted uptake. We have previously shown that the specific internalization is mediated by the interaction of the viral protein 1 unique region (VP1u) with a yet unknown cellular receptor. To locate the receptor-binding domain (RBD) within the VP1u, we analyzed the effect of truncations and mutations on the internalization capacity of the recombinant protein into UT7/Epo cells. Here we report that the N-terminal amino acids 5-80 of the VP1u are necessary and sufficient for cellular binding and internalization; thus, this N-terminal region represents the RBD required for B19V uptake. Using site-directed mutagenesis, we further identified a cluster of important amino acids playing a critical role in VP1u internalization. In silico predictions and experimental results suggest that the RBD is structured as a rigid fold of three α-helices. Finally, we found that dimerization of the VP1u leads to a considerably enhanced cellular binding and internalization. Taken together, we identified the RBD that mediates B19V uptake and mapped functional and structural motifs within this sequence. The findings reveal insights into the uptake process of B19V, which contribute to understand the pathogenesis of the infection and the neutralization of the virus by the immune system.

  1. ANALYSIS OF DIRECT AND INDIRECT EFFECTS OF FISCAL DECENTRALIZATION ON REGIONAL DISPARITY (CASE STUDY OF PROVINCES IN EASTERN AND WESTERN OF INDONESIA, 2006-2015

    Directory of Open Access Journals (Sweden)

    Faishal Fadli

    2016-12-01

    Full Text Available This study aimed to examine the direct and indirect effects of fiscal decentralization on regional disparity through economic growth in eastern and western Indonesia. The method used in this study is Path Analysis. The variables used in this study include the General Allocation Fund (DAU/Dana Alokasi Umum, Special Allocation Fund (DAK/Dana Alokasi Khusus, Revenue Sharing Fund (DBH/Dana Bagi Hasil, local revenue (PAD/Pendapatan Asli Daerah, Economic Growth (G, and regional disparity (IW. Comparing the analysis between eastern and western of Indonesia, the results show that there is no direct effect of fiscal decentralization on regional disparity and economic growth through direct fiscal decentralization on regional disparity in both eastern and western of Indonesia. However, using some measures of fiscal decentralization, in the case of eastern of Indonesia, DAU variable has significant effect whereas in the case of western Indonesia, DBH is the only one variable that has significant effect. This is consistent with the fact that composition of the balance funds disbursed by the central government to local governments, where the greatest composition of funds in eastern Indonesia come from the General Allocation Fund which reflects the dependence of local governments to the central government and for the western region of Indonesia, DBH is the greatest reflecting the independence of the local governments. As a result, to create fiscal decentralization working it is required a greater allocation of the fund balance.

  2. Why do savings institutions differ within the same region? The role of environment and social capital in the creation of savings arrangements in eastern Burkina Faso.

    NARCIS (Netherlands)

    Mazzucato, V.; Niemeijer, D

    2003-01-01

    The paper describes two different savings arrangements around cattle that have been developed in two villages in the eastern region of Burkina Faso and raises the question of why two forms have evolved in the same region, populated by the same ethnic groups, and where crop and livestock production

  3. Evaluating Coupled Human-Hydrologic Systems in High Altitude Regions: A Case Study of the Arun Watershed, Eastern Nepal

    Science.gov (United States)

    Voss, K.; Bookhagen, B.; Tague, C.; Lopez-Carr, D.

    2014-12-01

    The Himalaya exhibit dynamic ecological, hydrological, and climatic extremes that magnify the variability and extent of natural hazards, resulting in destruction to both physical and human landscapes. Coupled with poverty, these factors intensify local communities' vulnerability to climate change. This study highlights the Arun watershed in eastern Nepal as a case study to evaluate how local communities in high altitude regions are managing their water for domestic and agricultural needs while coping with extreme events, such as floods and landslides. Remotely-sensed precipitation, snowpack and glacial extent data from the past decade are combined with preliminary results from extensive field-based community surveys in the Arun watershed. The analysis of remotely-sensed data will describe seasonal trends in water availability, glacial lake growth, and the spatial variation of these trends within the basin. These hydrologic changes will be linked to the human survey analysis, which will provide an understanding of locals' perceptions of water challenges and the current water management strategies within the basin. Particular attention will be given to a comparison between the eastern and western tributaries of the Arun River, where the catchments are mainly rain-fed (eastern) versus glacial-fed (western). This contrast will highlight how different hydrologic scenarios evidenced from remote-sensing data motivate diverse human water management responses as defined in field surveys. A particular focus will be given to management decisions related to agriculture expansion and hydropower development. This synthesis of remote-sensing and social research methodologies provides a valuable perspective on coupled human-hydrologic systems.

  4. Examining HIV/AIDS provider stigma: assessing regional concerns in the islands of the Eastern Caribbean.

    Science.gov (United States)

    Abell, N; Rutledge, S E; McCann, T J; Padmore, J

    2007-02-01

    HIV/AIDS provider stigma has been understudied in the context of prevention, testing, and treatment. Results of a survey of persons associated with HIV/AIDS education, health care, and social service delivery in the Eastern Caribbean are described. Reliable constructs were observed for warmth towards PLHA, comfort in association with them, tendencies to distance from or condemn them, beliefs in viral transmission myths, and perceived capacity to counsel effectively. Most discrimination was directed towards MSM and IDUs. Providers whose roles were likely to involve touch felt less comfortable around PLHA and more likely to distance from and condemn them than providers whose roles were not. Implications for improved measurement and incorporation of mindfulness techniques in stigma intervention are discussed.

  5. Sedimentology and geochemistry of mud volcanoes in the Anaximander Mountain Region from the Eastern Mediterranean Sea.

    Science.gov (United States)

    Talas, Ezgi; Duman, Muhammet; Küçüksezgin, Filiz; Brennan, Michael L; Raineault, Nicole A

    2015-06-15

    Investigations carried out on surface sediments collected from the Anaximander mud volcanoes in the Eastern Mediterranean Sea to determine sedimentary and geochemical properties. The sediment grain size distribution and geochemical contents were determined by grain size analysis, organic carbon, carbonate contents and element analysis. The results of element contents were compared to background levels of Earth's crust. The factors that affect element distribution in sediments were calculated by the nine push core samples taken from the surface of mud volcanoes by the E/V Nautilus. The grain size of the samples varies from sand to sandy silt. Enrichment and Contamination factor analysis showed that these analyses can also be used to evaluate of deep sea environmental and source parameters. It is concluded that the biological and cold seep effects are the main drivers of surface sediment characteristics from the Anaximander mud volcanoes. Copyright © 2015 Elsevier Ltd. All rights reserved.

  6. A retrospective audit of antibiotic prescriptions in primary health-care facilities in Eastern Region, Ghana

    DEFF Research Database (Denmark)

    Ahiabu, Mary-Anne; Tersbøl, Britt Pinkowski; Biritwum, Richard

    2016-01-01

    with the national average estimated in 2008. Interventions that reduce diagnostic uncertainty in illness management should be considered. The National Health Insurance Scheme, as the main purchaser of health services in Ghana, offers an opportunity that should be exploited to introduce policies in support......Resistance to antibiotics is increasing globally and is a threat to public health. Research has demonstrated a correlation between antibiotic use and resistance development. Developing countries are the most affected by resistance because of high infectious disease burden, limited access to quality...... assured antibiotics and more optimal drugs and poor antibiotic use practices. The appropriate use of antibiotics to slow the pace of resistance development is crucial. The study retrospectively assessed antibiotic prescription practices in four public and private primary health-care facilities in Eastern...

  7. Frequency domain design of gain scheduling control for large wind systems in full-load region

    International Nuclear Information System (INIS)

    Burlibaşa, A.; Ceangă, E.

    2014-01-01

    Highlights: • A large wind energy system, operating under full-load regime, is considered. • According to its particularities in frequency domain, control law design is provided. • These particularities are influenced by the interactions of wind–tower–blade ensemble. • Control low, within gain scheduling strategy, is achieved imposing stability reserve. • Supplementary a criterion, aimed at reducing mechanical loads, is imposed. - Abstract: The paper presents the issue of power control law synthesis, in the case of a large wind system that operates under full-load regime, based on dynamic properties details in frequency domain. Solving this problem involves two phases: the establishment of a linearized model as faithfully as possible in various operating points of the full-load region, and synthesis of the power controller, considered with classic structure, taking into account frequency particularities of the obtained linearized model. Obtained linear model of the controlled process is of order 16 and encloses subsystems for tower fore-aft oscillations damping, and for drive-train torsion oscillations damping. The designed controller contains a PI component and a lag compensator for dynamic correction at high frequencies. It is known that the main features of wind system dynamics generated by the interaction of wind–tower–blade ensemble cause a gap in the gain characteristic of the model and complex conjugate zeros, which can move between right and left half-planes, depending on the average wind speed value. Consequently, for control law synthesis an interactive frequency solution is adopted. This is “transparent” in relation to particularities induced by wind–tower–blade interaction. This solution allows evaluation of the extent to which control law is affected by the subsystem for tower oscillations damping. Given the strong dependence between the model and the mean wind speed value, a gain scheduling control law is designed. At

  8. Use of a time-domain electromagnetic method with geochemical tracers to explore the salinity anomalies in a small coastal aquifer in north-eastern Tunisia

    Science.gov (United States)

    Chekirbane, Anis; Tsujimura, Maki; Kawachi, Atsushi; Lachaal, Fethi; Isoda, Hiroko; Tarhouni, Jamila

    2014-12-01

    The study area is a small coastal plain in north-eastern Tunisia. It is drained by an ephemeral stream network and is subject to several pollutant discharges such as oilfield brine coming from a neighboring oil company and wastewater from Somâa city, located in the upstream of the plain. Furthermore, a hydraulic head near the coastal part of the aquifer is below sea level, suggesting that seawater intrusion may occur. A time-domain electromagnetic (TDEM) survey, based on 28 soundings, was conducted in Wadi Al Ayn and Daroufa plains to delineate the saline groundwater. Based on longitudinal and transversal resistivity two-dimensional pseudosections calibrated with boring data, the extent of saline water was identified. Geochemical tracers were combined with the resistivity dataset to differentiate the origin of groundwater salinization. In the upstream part of the plain, the infiltration of oilfield brine through the sandy bed of Wadi Al Ayn seems to have a considerable effect on groundwater salinization. However, in the coastal part of the aquifer, groundwater salinization is due to seawater intrusion and the saltwater is reaching an inland extent around 1.3 km from the shoreline. The contribution ratios of saline water bodies derived from the inverted chloride data vary for the oilfield brine from 1 to 13 % and for the seawater from 2 to 21 %.

  9. On the forcing mechanisms of mesocyclones in the eastern Weddell Sea region, Antarctica: Process studies using a mesoscale numerical model

    Directory of Open Access Journals (Sweden)

    Thomas Klein

    2001-04-01

    Full Text Available Development mechanisms of Antarctic mesocyclones in the eastern Weddell Sea area are examined by means of simulations with a mesoscale model using different idealized initial conditions. In one of the experiments, a mesocyclone develops over an area of open water close to the coast of the Antarctic continent. The forcing mechanisms of this mesocyclogenesis are investigated by means of sensitivity studies in which certain physical processes and the relevance of the surface conditions topography, sea surface temperature and sea ice coverage are examined. The sensitivity experiments show that the simulated mesocyclone is forced by an interaction of several forcing mechanisms at different stages of the development rather than by a single mechanism. The topography of the eastern Weddell Sea region and the summertime coastal polynia are shown to be of great importance for the mesocyclogenesis. A suitable synoptic-scale flow is necessary to support the katabatic flow over the sloped ice sheet, and to enhance the generation of cyclonic vorticity due to vertical stretching for the initial mesocyclogenesis. The diabatic process of the convergence of the sensible and latent heat fluxes in the boundary layer over the coastal polynia then becomes the dominant forcing mechanism for the further development of the mesocyclone.

  10. NW-SE Pliocene-Quaternary extension in the Apan-Acoculco region, eastern Trans-Mexican Volcanic Belt

    Science.gov (United States)

    García-Palomo, Armando; Macías, José Luis; Jiménez, Adrián; Tolson, Gustavo; Mena, Manuel; Sánchez-Núñez, Juan Manuel; Arce, José Luis; Layer, Paul W.; Santoyo, Miguel Ángel; Lermo-Samaniego, Javier

    2018-01-01

    The Apan-Acoculco area is located in the eastern portion of the Mexico basin and the Trans-Mexican Volcanic Belt. The area is transected by right-stepping variably dipping NE-SW normal faults. The Apan-Tlaloc Fault System is a major discontinuity that divides the region into two contrasting areas with different structural and volcanic styles. a) The western area is characterized by a horst-graben geometry with widespread Quaternary monogenetic volcanism and scattered outcrops of Miocene and Pliocene rocks. b) The eastern area is dominated by tilted horsts with a domino-like geometry with widespread Miocene and Pliocene rocks, scattered Quaternary monogenetic volcanoes and the Acoculco Caldera. Gravity data suggest that this structural geometry continues into the Mesozoic limestones. Normal faulting was active since the Pliocene with three stages of extension. One of them, an intense dilatational event began during late Pliocene and continues nowadays, contemporaneously with the emplacement of the Apan-Tezontepec Volcanic Field and the Acoculco caldera. Statistical analysis of cone elongation, cone instability, and the kinematic analysis of faults attest for a NW50°SE ± 7° extensional regime in the Apan-Acoculco area. The activity in some portions of the Apan-Tlaloc Fault System continues today as indicated by earthquake swarms recorded in 1992 and 1996, that disrupted late Holocene paleosols, and Holocene volcanism.

  11. Using the Landsat data archive to assess long-term regional forest dynamics assessment in Eastern Europe, 1985-2012

    Science.gov (United States)

    Turubanova, S.; Potapov, P.; Krylov, A.; Tyukavina, A.; McCarty, J. L.; Radeloff, V. C.; Hansen, M. C.

    2015-04-01

    Dramatic political and economic changes in Eastern European countries following the dissolution of the "Eastern Bloc" and the collapse of the Soviet Union greatly affected land-cover and land-use trends. In particular, changes in forest cover dynamics may be attributed to the collapse of the planned economy, agricultural land abandonment, economy liberalization, and market conditions. However, changes in forest cover are hard to quantify given inconsistent forest statistics collected by different countries over the last 30 years. The objective of our research was to consistently quantify forest cover change across Eastern Europe from 1985 until 2012 using the complete Landsat data archive. We developed an algorithm for processing imagery from different Landsat platforms and sensors (TM and ETM+), aggregating these images into a common set of multi-temporal metrics, and mapping annual gross forest cover loss and decadal gross forest cover gain. Our results show that forest cover area increased from 1985 to 2012 by 4.7% across the region. Average annual gross forest cover loss was 0.41% of total forest cover area, with a statistically significant increase from 1985 to 2012. Most forest disturbance recovered fast, with only 12% of the areas of forest loss prior to 1995 not being recovered by 2012. Timber harvesting was the main cause of forest loss. Logging area declined after the collapse of socialism in the late 1980s, increased in the early 2000s, and decreased in most countries after 2007 due to the global economic crisis. By 2012, Central and Baltic Eastern European countries showed higher logging rates compared to their Western neighbours. Comparing our results with official forest cover and change estimates showed agreement in total forest area for year 2010, but with substantial disagreement between Landsat-based and official net forest cover area change. Landsat-based logging areas exhibit strong relationship with reported roundwood production at national

  12. U-Pb age in zircon of intrusive granite at Acopiara complex, Crystal region, domain Central Ceara, Brazil

    International Nuclear Information System (INIS)

    Neri, T.F.O.; Hamelak, G.M.S.; Azevedo, L.R.; Mattos, I.C.; Verissimo, C.U.V.; Nogueira Neto, J.A.; Lima, M.N.

    2015-01-01

    Granitic body mineralogically composed by two micas, located at Crystal region, Ceara Central domain and intruded into lithotypes from Acopiara complex, provided an age of ∼526 Ma, indicating important period of magma generation of granitic composition associated with crustal anatexia, during Paleozoic

  13. Advancing Tobacco Dependence Treatment Services in the Eastern Mediterranean Region: International collaboration for training and capacity-building

    Directory of Open Access Journals (Sweden)

    Feras I. Hawari

    2014-10-01

    Full Text Available Tobacco use negatively affects health and is a major risk factor for non-communicable diseases (NCDs. Today, tobacco use ranks third among risk factors in North Africa and the Middle East in terms of disease burden. Despite the established need for these services, tobacco dependence treatment (TDT services are still inadequate in the Eastern Mediterranean region (EMR. Among the main challenges hindering their expansion is the current lack of training opportunities. The provision of training and capacity-building—a key enabler of TDT—offers an excellent catalyst to launch TDT services in the region. This review discusses the need for TDT training in the EMR and describes a model for providing regional evidence-based training in line with international standards. The King Hussein Cancer Center in Amman, Jordan, is the regional host for Global Bridges, a worldwide TDT initiative. Using this model, they have trained 1,500 professionals and advocates from the EMR over the past three years.

  14. Erosion Associated with Seismically-Induced Landslides in the Middle Longmen Shan Region, Eastern Tibetan Plateau, China

    Directory of Open Access Journals (Sweden)

    Zhikun Ren

    2017-08-01

    Full Text Available The 2008 Wenchuan earthquake and associated co-seismic landslide was the most recent expression of the rapid deformation and erosion occurring in the eastern Tibetan Plateau. The erosion associated with co-seismic landslides balances the long-term tectonic uplift in the topographic evolution of the region; however, the quantitative relationship between earthquakes, uplift, and erosion is still unknown. In order to quantitatively distinguish the seismically-induced erosion in the total erosion, here, we quantify the Wenchuan earthquake-induced erosion using the digital elevation model (DEM differential method and previously-reported landslide volumes. Our results show that the seismically-induced erosion is comparable with the pre-earthquake short-term erosion. The seismically-induced erosion rate contributes ~50% of the total erosion rate, which suggests that the local topographic evolution of the middle Longmen Shan region may be closely related to tectonic events, such as the 2008 Wenchuan earthquake. We propose that seismically-induced erosion is a very important component of the total erosion, particularly in active orogenic regions. Our results demonstrate that the remote sensing technique of differential DEM provides a powerful tool for evaluating the volume of co-seismic landslides produced in intermountain regions by strong earthquakes.

  15. The Socioeconomic and Demographic Features of Children with Cerebral Palsi Applied to our Centre from Southern Eastern Anatolian Region

    Directory of Open Access Journals (Sweden)

    Sedat Nacitarhan

    2005-01-01

    Full Text Available Cerebral palsy is a general term which is used to describe a group of disorders that define muscle control impairment due to lesion in the developing brain. The aim of the present study was to indicate the common features of the children with cerebral palsy and their families in South Eastern region of Turkey, the most underdeveloped community in our country. In addition, the rate of marriage between the relatives (consanguineous marriage is higher in this region than the other regions.A total of 258 children with a diagnosis of cerebral palsy were enrolled to our study. These children were born in South Eastern Anatolian region and live here throughout their childhood. Their families were also living in this region. The members of the families were interviewed with the questionnaire to obtain information. Statistical analysis of the results was performed with Graphpad Prism Ver 3.00.68.99 percent of the patients in our study were men, and 31.01 percent were women. They were between the ages of 10-375 months, average was 75.43±59.15 months. Rate of people, who was not under any social security guarantee, was 15.5%. 50.3% of mothers were not literate. Families’ income was 8.5% good, 42.6% poor. In families, there was 33.3% rate of relationship between partners (consanguineous marriage. In 15.5% of families, there was another retarded child. 55 percent of mothers were never been under health check in pregnancy period. Retarded child was usually from first delivery (26.3%. 3.1% of our patients had twin pregnancy. Only 59,6% of the whole births were given at the hospital or by the help of a midwife. Children were suckled along 6.4±6.4 months. Only 8,5% of the children were being educated.Finally, we concluded that reducing convertible risk factors caused by the low education level of our region, underdeveloped socioeconomic conditions and some traditions (e.g. consanguineous marriage and delivery in house instead of health organization has

  16. Etiology of Pancytopenia: An observation from a referral medical institution of Eastern Region of India

    Directory of Open Access Journals (Sweden)

    Senjuti Dasgupta

    2015-01-01

    Conclusion: Aplastic anemia was found to be the most common cause of pancytopenia in this study, which is in contrast to studies conducted from other regions of India. Delineation of etiologies of pancytopenia in various regions can help in defining diagnostic and therapeutic strategies, which is expected to contribute toward the better management of such patients.

  17. Emerging and Reemerging Diseases in the World Health Organization (WHO) Eastern Mediterranean Region-Progress, Challenges, and WHO Initiatives.

    Science.gov (United States)

    Buliva, Evans; Elhakim, Mohamed; Tran Minh, Nhu Nguyen; Elkholy, Amgad; Mala, Peter; Abubakar, Abdinasir; Malik, Sk Md Mamunur Rahman

    2017-01-01

    The Eastern Mediterranean Region (EMR) of the World Health Organization (WHO) continues to be a hotspot for emerging and reemerging infectious diseases and the need to prevent, detect, and respond to any infectious diseases that pose a threat to global health security remains a priority. Many risk factors contribute in the emergence and rapid spread of epidemic diseases in the Region including acute and protracted humanitarian emergencies, resulting in fragile health systems, increased population mobility, rapid urbanization, climate change, weak surveillance and limited laboratory diagnostic capacity, and increased human-animal interaction. In EMR, several infectious disease outbreaks were detected, investigated, and rapidly contained over the past 5 years including: yellow fever in Sudan, Middle East respiratory syndrome in Bahrain, Oman, Qatar, Saudi Arabia, United Arab Emirates, and Yemen, cholera in Iraq, avian influenza A (H5N1) infection in Egypt, and dengue fever in Yemen, Sudan, and Pakistan. Dengue fever remains an important public health concern, with at least eight countries in the region being endemic for the disease. The emergence of MERS-CoV in the region in 2012 and its continued transmission currently poses one of the greatest threats. In response to the growing frequency, duration, and scale of disease outbreaks, WHO has worked closely with member states in the areas of improving public health preparedness, surveillance systems, outbreak response, and addressing critical knowledge gaps. A Regional network for experts and technical institutions has been established to facilitate support for international outbreak response. Major challenges are faced as a result of protracted humanitarian crises in the region. Funding gaps, lack of integrated approaches, weak surveillance systems, and absence of comprehensive response plans are other areas of concern. Accelerated efforts are needed by Regional countries, with the continuous support of WHO, to

  18. The psychosocial environment at work: an assessment of the World Health Organization Regional Office for the Eastern Mediterranean.

    Science.gov (United States)

    Join, A; Saeed, K; Arnaout, S; Kortum, E

    2012-04-01

    Psychosocial risks are widely recognised as major challenges to occupational health and safety. The risk management approach, which starts with an assessment of the risk that they pose, is acknowledged as the most effective way of preventing and managing psychosocial risks at the workplace. This paper presents the findings and action taken following a risk assessment of psychosocial risks, at the World health Organization Regional Officeforthe Eastern Mediterranean (EMRO) and country offices, carried outon behalf of the Committee on Health and Safety in the Workplace in EMRO. The findings show that psychosocial risks pose a threat to the mental well-being of staff. Management and co-worker support, rewards, possibilities for development, and trust mitigate the negative impact of psychosocial risks. The results of this risk assessment are being used to develop interventions aimed at enhancing the sense of well-being of staff, initially through actions at the employee level.

  19. NAA of the 'Minoan pumice' at Thera and comparison to alluvial pumice deposits in the Eastern Mediterranean region

    International Nuclear Information System (INIS)

    Bichler, M.; Egger, H.; Preisinger, A.; Ritter, D.; Stastny, P.

    1997-01-01

    Neutron activation analysis was used to determine up to 30 elements in the pumice layers from the 'Minoan eruption' at Thera (Santorini, Greece). Mt Pilato (Lipari, Italy) and in alluvial pumice from coasts of the Eastern Mediterranean region. The morphologically well distinguishable layers of the 'Minoan pumice' were found to be of nearly similar composition in respect to the elements determined and their distribution patterns could therefore be used to identify a sample as Santorinian or not. Additionally, this method was applied to pumice lumps found during archaeological excavations in the Nile delta, Egypt. The results showed that two of the three Egyptian samples are products of the Minoan eruption at Thera and therefore chronologically useful. A second group of pumices collected at Antalya (Turkey), Crete (Greece) and also in Egypt was found to have a distinctly different composition and is therefore related to another volcanic event. (author)

  20. Distance Education Examination Management in a Lowly Resourced North-Eastern Region of Zambia: A Phenomenological Approach

    Directory of Open Access Journals (Sweden)

    Francis Simui

    2017-09-01

    Full Text Available This paper focuses on the management of distance education examination in a lowly resourced North-Eastern region of Zambia. The study applies Hermeneutic Phenomenology approach to generate and make sense of the data. It is the lived experiences of 2 invigilators and 66 students purposively selected that the study draws its insights from. Meaning within the generated data is elicited using the Chaos theory. Emerging from this study is a multiplicity of ingredients needed to effectively manage distance education examinations in a chaotic environment. The need for visionary leadership with a shared understanding of institutional purpose, the need for motivated staff with creativity and innovation and the need for effective communication are all vital ingredients needed to manage examinations. In conclusion, we now know that amidst chaos lay opportunities for innovation and creativity in terms of new strategies for managing distance education. To this extent, chaos should be treasured and not censured.

  1. Assessing the effectiveness of RegCM4 regional climate model in simulating the aerosol optical depth patterns over the region of Eastern Mediterranean

    Science.gov (United States)

    Georgoulias, Aristeidis K.; Tsikerdekis, Athanasios; Ntogras, Christos; Zanis, Prodromos

    2014-05-01

    In this work, the ability of the regional climate model RegCM4 to simulate the aerosol optical depth (AOD) patterns over the region of Eastern Mediterranean is assessed. Three separate runs were implemented within the framework of the QUADIEEMS project for the time period 2000-2010 at a horizontal resolution of 50km covering the region of Europe. ERA-interim data were used as lateral boundary conditions while the model was driven by emissions from CMIP5. In the first case, the total of the aerosol types that RegCM4 accounts for were included (sulfate, black carbon, sea salt, dust), while in the other two cases only anthropogenic and dust particles were taken into account, respectively. The total AOD patterns were compared against level-2 satellite observations from MODIS TERRA and AQUA and ground-based measurements from 12 AERONET sites located in the region. In addition, the RegCM4 anthropogenic and dust AOD patterns were compared against the anthropogenic and dust component of MODIS AOD which was calculated using a combination of various satellite, model and reanalysis products. Our results indicate a significant underestimation of the anthropogenic AOD, while, on the contrary, the dust AOD fields are simulated in a more efficient way. The QUADIEEMS project is co-financed by the European Social Fund (ESF) and national resources under the operational programme Education and Lifelong Learning (EdLL) within the framework of the Action "Supporting Postdoctoral Researchers".

  2. Mother-to-child transmission of hepatitis B: extent of knowledge of physicians and midwives in Eastern region of Ghana

    Directory of Open Access Journals (Sweden)

    Charles Ampong Adjei

    2016-07-01

    Full Text Available Abstract Background Mother -to -Child transmission of hepatitis B infection remains a major public health concern particularly in Africa. Adequate knowledge of physicians and midwives is crucial in averting most of the hepatitis B viral transmissions from mothers to their new-borns. However, there is a dearth of evidence on extent of knowledge of physicians and midwives in Ghana inspite of the increasing incidence of hepatitis B infection in the country. This study therefore assessed the knowledge level of physicians and midwives regarding Mother-to-Child transmission of hepatitis B in the Eastern region of Ghana. Methods A Cross sectional survey was conducted between August to November, 2015 using semi-structured self-administered questionnaire. Study participants were recruited from five health facilities and their level of awareness and knowledge about Mother-to-Child transmission of hepatitis B were assessed. The level of statistical significance was set at 0.05 alpha level. Results The findings showed that both physicians and midwives had good knowledge on Mother-to-Child transmission of hepatitis B infection. However, there were some knowledge gaps regarding effective hepatitis B prevention from mother to their newborns such as the use of hepatitis B vaccine and immunoglobulin. Additionally, 49.2 % (n = 62 of the participants had never attended any workshop on Mother-to-Child transmission of hepatitis B since completion of formal training. Conclusions Developing appropriate periodic training programmes on current issues of hepatitis B for physicians and midwives in Eastern region will further enhance their knowledge. It is recommended that, further study examine if the knowledge of the respondents is translated into practice.

  3. Tobacco advertising, promotion and sponsorship in entertainment media: a phenomenon requiring stronger controls in the Eastern Mediterranean Region.

    Science.gov (United States)

    El-Awa, Fatimah M S; El Naga, Randa Abou; Labib, Sahar; Latif, Nisreen Abdel

    2018-04-05

    Tobacco use and placement of tobacco products in television (TV) productions and movies is a way to promote tobacco use while avoiding tobacco advertising bans that exist in most countries. The fact that such productions are broadcast widely and viewed by millions, including children and young people, is of concern. This paper reviews the evidence on the use of tobacco advertising, promotion and sponsorship (TAPS) in TV and films in the Eastern Mediterranean Region and the ways to combat it. Evidence from Egypt shows considerable and increasing use of tobacco products by actors on screen, including female actors, in programmes aired during Ramadan in 2015-2017. A study of Iranian movies in 2015 showed that tobacco scenes in Iranian movies were increasing. In 2014, the WHO Regional Office for the Eastern Mediterranean held a consultative meeting on TAPS in drama. The consultation recommended regulating the tobacco presence in movies and TV through complete implementation of Article 13 of the WHO FCTC, and raising the issue to the WHO FCTC Conference of the Parties. In 2016, the Conference of the Parties called on parties to consider scaling up the implementation of WHO FCTC Article 13 and monitoring the use of TAPS in entertainment media in accordance with national legislation. A comprehensive approach is essential to end the tobacco industry's use of TV productions and movies to promote their products. Copyright © World Health Organization (WHO) 2018. Some rights reserved. This work is available under the CC BY-NC-SA 3.0 IGO license (https://creativecommons.org/licenses/by-nc-sa/3.0/igo).

  4. Diagnostic and management practices for phenylketonuria in 19 countries of the South and Eastern European Region: survey results.

    Science.gov (United States)

    Giżewska, Maria; MacDonald, Anita; Bélanger-Quintana, Amaya; Burlina, Alberto; Cleary, Maureen; Coşkun, Turgay; Feillet, François; Muntau, Ania C; Trefz, Friedrich K; van Spronsen, Francjan J; Blau, Nenad

    2016-02-01

    To avoid potentially severe outcomes, phenylketonuria (PKU) must be detected as soon as possible after birth and managed with life-long treatment. A questionnaire-based survey was performed to document diagnosis and management practices for PKU in a region of Southern and Eastern Europe. Prevalence and management data were obtained from 37/59 (63 %) centres within 19/22 (86%) contacted countries (N = 8600 patients). The main results' analysis was based on completed questionnaires obtained from 31 centres (53%) within 15 countries (68%). A median of 10 % of patients per centre had been diagnosed after the newborn period. Metabolic dieticians and specialised adult PKU clinics were lacking in 36 and 84% of centres, respectively. In 26% of centres, treatment initiation was delayed until >15 days of life. Blood phenylalanine (Phe) thresholds to start treatment and upper Phe targets were inconsistent across centres. Ten percent of centres reported monitoring Phe every 2 weeks for pregnant women with PKU, which is insufficient to minimise risk of neonatal sequalae. Sapropterin dihydrochloride treatment was available in 48% of centres, with 24-h responsiveness tests most common (36%). Only one centre among the five countries lacking newborn screening provided a completed questionnaire. Targeted efforts by health care professionals and governments are needed to optimise diagnostic and management approaches for PKU in Southern and Eastern Europe. PKU must be detected early and optimally managed throughout life to avoid poor outcomes, yet newborn screening is not universal and diagnostic and management practices for PKU are known to vary widely between different centres and countries. Targeted efforts by health care professionals and governments are needed to optimise diagnostic and management approaches. PKU management practices are documented in 19 South and Eastern European countries indicating a heterogeneous situation across the region. Key areas for improvement

  5. Regional Fears of Western Primacy and the Future of U.S. Middle Eastern Basing Policy

    National Research Council Canada - National Science Library

    Terrill, W. A

    2006-01-01

    .... Until at least the 1940s, imperial powers often maintained that these bases were designed to defend regional nations against foreign invaders, but they also were used to pressure and sometimes...

  6. Regional Markets for Non-timber Forest Products in Eastern Brazilian Amazon

    OpenAIRE

    Vuola, Matleena

    2013-01-01

    While export of non-timber forest products (NTFPs) has been promoted as a sustainable development strategy, the literature suggests that local and regional markets are also potentially important, not only for producers but also for traders and consumers (Shackleton et al. 2007). For producers, regional markets are thought to offer more accessible and more stable markets, while for traders, these markets offer employment, and for consumers, reasonably priced, diverse, fresh food. Consumptio...

  7. Peculiar long-range supercurrent in superconductor-ferromagnet-superconductor junction containing a noncollinear magnetic domain in the ferromagnetic region

    Energy Technology Data Exchange (ETDEWEB)

    Meng, Hao, E-mail: menghao1982@shu.edu.cn [School of Physics and Telecommunication Engineering, Shaanxi University of Technology, Hanzhong 723001 (China); National Laboratory of Solid State Microstructures and Department of Physics, Nanjing University, Nanjing 210093 (China); Wu, Xiuqiang [National Laboratory of Solid State Microstructures and Department of Physics, Nanjing University, Nanjing 210093 (China); Ren, Yajie [School of Physics and Telecommunication Engineering, Shaanxi University of Technology, Hanzhong 723001 (China)

    2015-01-14

    We study the supercurrent in clean superconductor-ferromagnet-superconductor heterostructure containing a noncollinear magnetic domain in the ferromagnetic region. It is demonstrated that the magnetic domain can lead to a spin-flip scattering process, which reverses the spin orientations of the singlet Cooper pair and simultaneously changes the sign of the corresponding electronic momentum. If the ferromagnetic layers on both sides of magnetic domain have the same features, the long-range proximity effect will take place. That is because the singlet Cooper pair will create an exact phase-cancellation effect and gets an additional π phase shift as it passes through the entire ferromagnetic region. Then, the equal spin triplet pair only exists in the magnetic domain region and can not diffuse into the other two ferromagnetic layers. So, the supercurrent mostly arises from the singlet Cooper pairs, and the equal spin triplet pairs are not involved. This result can provide a approach for generating the long-range supercurrent.

  8. Assessment of regional climatic changes in the Eastern Himalayan region: a study using multi-satellite remote sensing data sets.

    Science.gov (United States)

    Agrawal, Anubha; Sharma, Anu Rani; Tayal, Shresth

    2014-10-01

    In this study, an attempt has been made to capture the sensitivity of a mountainous region to elevation-dependent warming and the response of a glacier-laden surface to increasing greenhouse gases (GHGs) and aerosol concentration. Some of the changes Sikkim has undergone due to urban sprawl are as follows: an increase of ~0.7 ± 0.46 °C temperature in the past 40 years at an altitude of 5.5 km; a 2.21 km(2)/year rate of loss of glacierised area in the past 33 years; an increase in absorbed longwave radiation (6 ± 2.41 W/m(2)); an increase in heat fluxes (2 ± 0.97 W/m(2)); a decrease in albedo during the last 30 years; an increase in the concentrations of carbon dioxide (4.42%), methane (0.61%), ozone (0.67%) and black carbon column optical depth (7.19%); a decrease in carbon monoxide (2.61%) and an increase in aerosol optical depth (19.16%) during the last decade; a decrease in precipitation, water yield, discharge and groundwater; and an increase in evapotranspiration during 1971-2005. Detection of three climate signals (1976, 1997 and 2005) in the entire analysis is the quantification of the fact that the climate of Sikkim is moving away from its inter-annual variability. An increase in temperature (0.23 °C/decade) at higher altitude (~5.5 km), suppression of precipitation, decreasing water availability and rapid loss of glacierised area are the evidences of the fact that air pollution is playing a significant role in bringing about regional climatic changes in Sikkim. In this study, change detection method has been used for the first time for the estimation of change in a glacierised area of the region.

  9. Spatio-temporal patterns of distribution of West Nile virus vectors in eastern Piedmont Region, Italy

    Directory of Open Access Journals (Sweden)

    Bisanzio Donal

    2011-12-01

    Full Text Available Abstract Background West Nile Virus (WNV transmission in Italy was first reported in 1998 as an equine outbreak near the swamps of Padule di Fucecchio, Tuscany. No other cases were identified during the following decade until 2008, when horse and human outbreaks were reported in Emilia Romagna, North Italy. Since then, WNV outbreaks have occurred annually, spreading from their initial northern foci throughout the country. Following the outbreak in 1998 the Italian public health authority defined a surveillance plan to detect WNV circulation in birds, horses and mosquitoes. By applying spatial statistical analysis (spatial point pattern analysis and models (Bayesian GLMM models to a longitudinal dataset on the abundance of the three putative WNV vectors [Ochlerotatus caspius (Pallas 1771, Culex pipiens (Linnaeus 1758 and Culex modestus (Ficalbi 1890] in eastern Piedmont, we quantified their abundance and distribution in space and time and generated prediction maps outlining the areas with the highest vector productivity and potential for WNV introduction and amplification. Results The highest abundance and significant spatial clusters of Oc. caspius and Cx. modestus were in proximity to rice fields, and for Cx. pipiens, in proximity to highly populated urban areas. The GLMM model showed the importance of weather conditions and environmental factors in predicting mosquito abundance. Distance from the preferential breeding sites and elevation were negatively associated with the number of collected mosquitoes. The Normalized Difference Vegetation Index (NDVI was positively correlated with mosquito abundance in rice fields (Oc. caspius and Cx. modestus. Based on the best models, we developed prediction maps for the year 2010 outlining the areas where high abundance of vectors could favour the introduction and amplification of WNV. Conclusions Our findings provide useful information for surveillance activities aiming to identify locations where the

  10. HYDROGEOLOGICAL AND HYDROGEOCHEMICAL CHARACTERISTICS OF A WIDER AREA OF THE REGIONAL WELL FIELD EASTERN SLAVONIA – SIKIREVCI

    Directory of Open Access Journals (Sweden)

    Jasna Kopić

    2016-10-01

    Full Text Available This paper establishes hydrogeological and hydrogeochemical characteristics of a wider area of the regional well field Eastern Slavonia - Sikirevci. The research was conducted based on data gathered from the area of the Federation of Bosnia and Herzegovina and the Republic of Croatia. The aquifer Velika Kopanica is situated at the territory of the Republic of Croatia in the triangular region formed between Kopanica, Gundinci and Kruševica. The River Sava partially flows through it and the aquifer extends beneath the river to the territory of the Federation of Bosnia and Herzegovina from Donji Svilaj in the West to Domaljevac in the East where its yield is the highest. The thickness of the aquifer decreases towards the water body Odžak. It was determined that the groundwater which is extracted from wells of the wider area of the regional well field contains iron, manganese, natural ammonia and arsenic in values exceeding the maximum allowable concentration for drinking water. The increased values of these parameters are a result of mineral composition and reductive conditions in the aquifer environment. By means of a multivariate statistic cluster analysis, an overview of groups of elements is provided based on geochemical affinity and/or origin.

  11. Lithologic influences on groundwater recharge through incised glacial till from profile to regional scales: Evidence from glaciated Eastern Nebraska

    Science.gov (United States)

    Gates, John B.; Steele, Gregory V.; Nasta, Paolo; Szilagyi, Jozsef

    2014-01-01

    Variability in sediment hydraulic properties associated with landscape depositional and erosional features can influence groundwater recharge processes by affecting soil-water storage and transmission. This study considers recharge to aquifers underlying river-incised glaciated terrain where the distribution of clay-rich till is largely intact in upland locations but has been removed by alluvial erosion in stream valleys. In a stream-dissected glacial region in eastern Nebraska (Great Plains region of the United States), recharge estimates were developed for nested profile, aquifer, and regional scales using unsaturated zone profile measurements (matric potentials, Cl- and 3H), groundwater tracers (CFC-12 and SF6), and a remote sensing-assisted water balance model. Results show a consistent influence of till lithology on recharge rates across nested spatial scales despite substantial uncertainty in all recharge estimation methods, suggesting that minimal diffuse recharge occurs through upland glacial till lithology whereas diffuse recharge occurs in river valleys where till is locally absent. Diffuse recharge is estimated to account for a maximum of 61% of total recharge based on comparison of diffuse recharge estimated from the unsaturated zone (0-43 mm yr-1) and total recharge estimated from groundwater tracers (median 58 mm yr-1) and water balance modeling (median 56 mm yr-1). The results underscore the importance of lithologic controls on the distributions of both recharge rates and mechanisms.

  12. Population aging from 1950 to 2010 in seventeen transitional countries in the wider region of South Eastern Europe

    Directory of Open Access Journals (Sweden)

    Mihajlo Jakovljevic

    2015-12-01

    Full Text Available Aim: Population aging has profoundly reshaped demographic landscapes in all South Eastern European (SEE countries. The aim of this study was to provide a thorough comparative inter-country assessment on the speed of population aging in the entire SEE region for the period 1950-2010. Methods: Descriptive observational analysis of long-term trends on core primary and composite indicators of population aging across seventeen countries of the wider SEE region, with panel data sets at a national level. Results: During the past six decades, the entire SEE region has experienced a rapid increase in the median age (from 25.2 years in 1950 to 37.9 years in 2010, with a simultaneous fall of fertility rates for two children per woman (from 3.55 children per each childbearing woman in 1950 to 1.49 in 2010, coupled with significant rise in the population of elderly citizens. The speed of population aging has vastly accelerated (with a 2.5 fold increase over the past three decades. The percentage of individuals over 65 years has doubled from 7% in 1950 to 14% in 2010. Conclusion: Complex national strategies are needed to cope with the shrinking labour force coupled with the growing proportion of the older population. With all likelihood, population aging will further accelerate in the near future. This profound long-term demographic transition will threaten financial sustainability of current health systems in all SEE countries.

  13. Statistical Comparison of Cloud and Aerosol Vertical Properties between Two Eastern China Regions Based on CloudSat/CALIPSO Data

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    Yujun Qiu

    2017-01-01

    Full Text Available The relationship between cloud and aerosol properties was investigated over two 4° × 4° adjacent regions in the south (R1 and in the north (R2 in eastern China. The CloudSat/CALIPSO data were used to extract the cloud and aerosol profiles properties. The mean value of cloud occurrence probability (COP was the highest in the mixed cloud layer (−40°C~0°C and the lowest in the warm cloud layer (>0°C. The atmospheric humidity was more statistically relevant to COP in the warm cloud layer than aerosol condition. The differences in COP between the two regions in the mixed cloud layer and ice cloud layer (<−40°C had good correlations with those in the aerosol extinction coefficient. A radar reflectivity factor greater than −10 dBZ occurred mainly in warm cloud layers and mixed cloud layers. A high-COP zone appeared in the above-0°C layer with cloud thicknesses of 2-3 km in both regions and in all the four seasons, but the distribution of the zonal layer in R2 was more continuous than that in R1, which was consistent with the higher aerosol optical thickness in R2 than in R1 in the above-0°C layer, indicating a positive correlation between aerosol and cloud probability.

  14. Geological documentation of the Norrkoeping-Oskarshamn region in south-eastern Sweden

    International Nuclear Information System (INIS)

    Scherman, S.

    1994-04-01

    This study comprises a compilation of data from two tectonic regions in southeastern Sweden and a presentation of geological factors judged to be of importance for the regional-scale siting of a high level nuclear waste repository. The study areas were selected to complement earlier investigations in that part of Sweden and to allow for an analysis of the transition zone between the Svecofennian subprovince and the Transcandinavian Igneous Belt (TIB). It should be noted that the studied regions have been investigated only to a limited extent (general surveying). More detailed information is needed if these regions are to be included in a siting program. It is recommended as a working strategy that the following characteristics and properties of relevance for repository siting are considered in a regional siting program. *Bedrock; historical evolution, rock-type distribution, dikes and grade of metamorphism. *Deformation history; plastic and brittle structures. The bedrock and its structural characteristics are of importance for the stability of the rock, the groundwater flow and the long term safety of the underground facility. *Quaternary deposits; characteristics and thickness. The quaternary characteristics may have an obscuring impact on some of the geophysical methods and is therefore important when selecting investigation methods. *Natural resources such as ore and mineral deposits, industrial minerals and ornamental stones. Of importance in order to minimize land use conflicts and as far as possible avoid future human intrusions. *Experiences from underground constructions in the actual region. This will give three-dimensional information on the bedrock and structures as well as the technical outcome from underground construction work. *Regional groundwater properties. Important for the understanding of large-scale gradient (topography) and of the variations of the groundwater chemistry. 24 refs

  15. Parameter transferability within homogeneous regions and comparisons with predictions from a priori parameters in the eastern United States

    Science.gov (United States)

    Chouaib, Wafa; Alila, Younes; Caldwell, Peter V.

    2018-05-01

    The need for predictions of flow time-series persists at ungauged catchments, motivating the research goals of our study. By means of the Sacramento model, this paper explores the use of parameter transfer within homogeneous regions of similar climate and flow characteristics and makes comparisons with predictions from a priori parameters. We assessed the performance using the Nash-Sutcliffe (NS), bias, mean monthly hydrograph and flow duration curve (FDC). The study was conducted on a large dataset of 73 catchments within the eastern US. Two approaches to the parameter transferability were developed and evaluated; (i) the within homogeneous region parameter transfer using one donor catchment specific to each region, (ii) the parameter transfer disregarding the geographical limits of homogeneous regions, where one donor catchment was common to all regions. Comparisons between both parameter transfers enabled to assess the gain in performance from the parameter regionalization and its respective constraints and limitations. The parameter transfer within homogeneous regions outperformed the a priori parameters and led to a decrease in bias and increase in efficiency reaching a median NS of 0.77 and a NS of 0.85 at individual catchments. The use of FDC revealed the effect of bias on the inaccuracy of prediction from parameter transfer. In one specific region, of mountainous and forested catchments, the prediction accuracy of the parameter transfer was less satisfactory and equivalent to a priori parameters. In this region, the parameter transfer from the outsider catchment provided the best performance; less-biased with smaller uncertainty in medium flow percentiles (40%-60%). The large disparity of energy conditions explained the lack of performance from parameter transfer in this region. Besides, the subsurface stormflow is predominant and there is a likelihood of lateral preferential flow, which according to its specific properties further explained the reduced

  16. Investigation of Radon in drinking water from wells of the North-Eastern region of Bosnia and Herzegovina

    International Nuclear Information System (INIS)

    Adrovic, Feriz; Dedic, Amela

    2008-01-01

    Some areas of the Tuzla region (B and H) suffer heavily from the shortage of quality drinking water. The only real long-term water resource in this region is the Lake Modrac, the largest accumulation lake in Bosnia and Herzegovina. Due to the fact that radon is soluble in water it can be transported by water to long distances. In cases of intake of waters rich in radon the most affected are sensitive cells within the abdomen and other internal organs. In order to satisfy the needs for drinking water, people are forced to excavate and drill wells. In the area of Tuzla region and the entire B and H excavated wells are very frequent, and so are drilled wells lately, due to more developed and cheaper technology for soil drilling. Such activities in this area, and the whole of B and H, are carried out in an unorderly manner and without previously completed chemical and radiological analyses of soil and water samples. The University of Tuzla formed the Laboratory for detection of radon in all environments, and the survey displayed in this paper have been the first investigation of that kind in B and H. Here we presented the results of radon survey of drinking waters from excavated and drilled wells in the area of Tuzla region (North-Eastern region of B and H). The measurements were conducted over the period of one year (2006), so as to make possible monitoring of variations of radon concentrations in dependence of meteorological changes. These investigation works showed that radon concentration at most locations was significantly higher in drilled wells than in excavated wells. Mean values of radon concentration in the tested water samples ranged within the interval of 101-4200 Bq/m 3 . Radon activity concentration was measured with the Alpha GAURD radon system (Genitron instruments-Frankfurt). (author)

  17. Galileo multispectral imaging of the north polar and eastern limb regions of the moon

    Science.gov (United States)

    Belton, M.J.S.; Greeley, R.; Greenberg, R.; McEwen, A.; Klaasen, K.P.; Head, J. W.; Pieters, C.; Neukum, G.; Chapman, C.R.; Geissler, P.; Heffernan, C.; Breneman, H.; Anger, C.; Carr, M.H.; Davies, M.E.; Fanale, F.P.; Gierasch, P.J.; Ingersoll, A.P.; Johnson, T.V.; Pilcher, C.B.; Thompson, W.R.; Veverka, J.; Sagan, C.

    1994-01-01

    Multispectral images obtained during the Galileo probe's second encounter with the moon reveal the compositional nature of the north polar regions and the northeastern limb. Mare deposits in these regions are found to be primarily low to medium titanium lavas and, as on the western limb, show only slight spectral heterogeneity. The northern light plains are found to have the spectral characteristics of highlands materials, show little evidence for the presence of cryptomaria, and were most likely emplaced by impact processes regardless of their age.Multispectral images obtained during the Galileo probe's second encounter with the moon reveal the compositional nature of the north polar regions and the northeastern limb. Mare deposits in these regions are found to be primarily low to medium titanium lavas and, as on the western limb, show only slight spectral heterogeneity. The northern light plains are found to have the spectral characteristics of highlands materials, show little evidence for the presence of cryptomaria, and were most likely emplaced by impact processes regardless of their age.

  18. Production of pulse in mono-cropped rice system in the coastal region of Eastern India

    International Nuclear Information System (INIS)

    Khan, A.R.; Nanda, P.; Chandra, Dinesh; Ghorai, A.K.; Behera, M.S.

    2001-04-01

    This experiment was undertaken with an objective to increase the yield of black-gram leguminous pulse crop through optimal doses of phosphatic fertilizer with supplemental irrigation in mono-cropped rice-fallow regions of India. Irrigation and phosphorus fertilizer application were introduced for enhancing productivity of black-gram to provide better returns to available water resources

  19. Situational analysis of tuberculosis control programs in the Eastern Mediterranean Region: Gaps and solutions

    Directory of Open Access Journals (Sweden)

    Samiha Baghdadi

    2016-01-01

    Conclusion: The year 2015 marks a transition from the MDGs to the Sustainable Development Goals and from the Stop TB Strategy to the End TB Strategy. The region will move into three main directions: complete pending tasks, mitigate the impact of the complex emergencies on TB control, and move toward TB elimination.

  20. Results of the radiological environmental monitoring network in the Central Eastern region of Cuba

    International Nuclear Information System (INIS)

    Montalvan Estrada, O.; Brigido Flores, R.; Rosa Suarez, R.; Barreras Caballero, A.; Damera Martinez, A.

    1998-01-01

    The radiological environmental monitoring laboratory of Camaguey is a member of the Cuban radiological environmental network and it has been carried out a series of measures about radioactivity in the atmosphere: gamma-dose rate, gross-beta activities in fallout and in aerosols. The results show that this region has a low radiological background and it has been exposure contamination

  1. 70 Bush Meat Trading in the Oban Hills Region of South-Eastern ...

    African Journals Online (AJOL)

    Choice-Academy

    2008-03-01

    Mar 1, 2008 ... diversity of faunal species of the region can be found in ... B. The traditional inclination of rural people to bush ... (types and kinds) or species of animals involved in the .... Apes and/or. Prosimians, Reptiles; Rodents; birds, etc).

  2. Assessing drought vulnerability and adaptation among farmers in Gadaref region, Eastern Sudan

    NARCIS (Netherlands)

    Mohmmed, Alnail; Li, Jianhua; Elaru, Joshua; Elbashier, Mohammed M.A.; Keesstra, Saskia; Artemi, Cerdà; Martin, Kabenge; Reuben, Makomere; Teffera, Zeben

    2018-01-01

    Agricultural productivity in rural areas is severely affected by climate variability, and this elevates the vulnerability of rural households to food insecurity. This study examines the socio-economic vulnerability of farmers who are susceptible to droughts in the five agricultural-based regions of

  3. A LigA three-domain region protects hamsters from lethal infection by Leptospira interrogans.

    Directory of Open Access Journals (Sweden)

    Mariana L Coutinho

    2011-12-01

    Full Text Available The leptospiral LigA protein consists of 13 bacterial immunoglobulin-like (Big domains and is the only purified recombinant subunit vaccine that has been demonstrated to protect against lethal challenge by a clinical isolate of Leptospira interrogans in the hamster model of leptospirosis. We determined the minimum number and location of LigA domains required for immunoprotection. Immunization with domains 11 and 12 was found to be required but insufficient for protection. Inclusion of a third domain, either 10 or 13, was required for 100% survival after intraperitoneal challenge with Leptospira interrogans serovar Copenhageni strain Fiocruz L1-130. As in previous studies, survivors had renal colonization; here, we quantitated the leptospiral burden by qPCR to be 1.2×10(3 to 8×10(5 copies of leptospiral DNA per microgram of kidney DNA. Although renal histopathology in survivors revealed tubulointerstitial changes indicating an inflammatory response to the infection, blood chemistry analysis indicated that renal function was normal. These studies define the Big domains of LigA that account for its vaccine efficacy and highlight the need for additional strategies to achieve sterilizing immunity to protect the mammalian host from leptospiral infection and its consequences.

  4. Eastern Baltic region vs. Western Europe: modelling age related changes in the pubic symphysis and the auricular surface.

    Science.gov (United States)

    Jatautis, Šarūnas; Jankauskas, Rimantas

    2018-02-01

    showed that the differences in the estimates from the reference data result in noticeably different age-at-death distributions in the target population. Thus, a degree bias may be expected if estimates from the western European reference data are used to collect information on ages at death in the eastern Baltic region based on the changes in the auricular surface. d) Moreover, the bias is expected to be more pronounced if the fitted regression model improperly describes the reference data. Conclusions. Differences in the timing of age-related changes in skeletal traits are to be expected among European reference samples, and cannot be ignored when seeking to reliably estimate an age-at-death distribution in the target population. This form of bias should be taken into consideration in further studies of skeletal samples from the eastern Baltic region.

  5. Contributions of gravity and field data on the structural scheme updating of the Tellian domain and its foreland (Nefza-Bizerte region, northern Tunisia)

    Science.gov (United States)

    Essid, El Mabrouk; Kadri, Ali; Balti, Hadhemi; Gasmi, Mohamed; Zargouni, Fouad

    2018-03-01

    The Nefza-Bizerte region, eastern part of the Tunisian Alpine chain, covers the thrust sheets domain called the Tell and its Atlassic foreland. The deep structures under the Tellian thrust sheets are not enough explored. The structural interpretation of magmatic rocks, Triassic outcrops and the depressions are still a subject of discussion. In this work, we intend to investigate deep faults and their eventual role in magmatism and Triassic salt setting up and to explain the depression genesis. Analysis of the Bouguer anomaly map and its derivatives reveals the main gravity lineaments, organized in major NE- and NW-trending systems. The NE-trending system, dipping towards the NW, is the main component of the structural scheme and has controlled the tectonic evolution of this area. After the immobilization of the Tellian thrust sheets during the uppermost Langhian, the Tell and its Atlassic foreland were affected by the Tortonian compressive event with a NW-trending maximum horizontal stress. The reverse kinematics of the NE-trending deep-seated faults created at their front continental environments filled later by post-nappes Neogene deposits. After the early Pleistocene, a NNW-directed compressional stress regime deformed the post-nappes Neogene series and generated NW-trending grabens. This coexistence of compression-extension continues until present day.

  6. Gating transitions in the selectivity filter region of a sodium channel are coupled to the domain IV voltage sensor.

    Science.gov (United States)

    Capes, Deborah L; Arcisio-Miranda, Manoel; Jarecki, Brian W; French, Robert J; Chanda, Baron

    2012-02-14

    Voltage-dependent ion channels are crucial for generation and propagation of electrical activity in biological systems. The primary mechanism for voltage transduction in these proteins involves the movement of a voltage-sensing domain (D), which opens a gate located on the cytoplasmic side. A distinct conformational change in the selectivity filter near the extracellular side has been implicated in slow inactivation gating, which is important for spike frequency adaptation in neural circuits. However, it remains an open question whether gating transitions in the selectivity filter region are also actuated by voltage sensors. Here, we examine conformational coupling between each of the four voltage sensors and the outer pore of a eukaryotic voltage-dependent sodium channel. The voltage sensors of these sodium channels are not structurally symmetric and exhibit functional specialization. To track the conformational rearrangements of individual voltage-sensing domains, we recorded domain-specific gating pore currents. Our data show that, of the four voltage sensors, only the domain IV voltage sensor is coupled to the conformation of the selectivity filter region of the sodium channel. Trapping the outer pore in a particular conformation with a high-affinity toxin or disulphide crossbridge impedes the return of this voltage sensor to its resting conformation. Our findings directly establish that, in addition to the canonical electromechanical coupling between voltage sensor and inner pore gates of a sodium channel, gating transitions in the selectivity filter region are also coupled to the movement of a voltage sensor. Furthermore, our results also imply that the voltage sensor of domain IV is unique in this linkage and in the ability to initiate slow inactivation in sodium channels.

  7. Extreme dust storm over the eastern Mediterranean in September 2015: satellite, lidar, and surface observations in the Cyprus region

    Directory of Open Access Journals (Sweden)

    R.-E. Mamouri

    2016-11-01

    Full Text Available A record-breaking dust storm originating from desert regions in northern Syria and Iraq occurred over the eastern Mediterranean in September 2015. In this contribution of a series of two articles (part 1, observations; part 2, atmospheric modeling, we provide a comprehensive overview of the aerosol conditions during this extreme dust outbreak in the Cyprus region. These observations are based on satellite observations (MODIS, moderate resolution imaging spectroradiometer of aerosol optical thickness (AOT and Ångström exponent, surface particle mass (PM10 concentrations measured at four sites in Cyprus, visibility observations at three airports in southern Cyprus and corresponding conversion products (particle extinction coefficient, dust mass concentrations, EARLINET (European Aerosol Research Lidar Network lidar observations of dust vertical layering over Limassol, particle optical properties (backscatter, extinction, lidar ratio, linear depolarization ratio, and derived profiles of dust mass concentrations. Maximum 550 nm AOT exceeded values of 5.0, according to MODIS, and the mass loads were correspondingly >  10 g m−2 over Larnaca and Limassol during the passage of an extremely dense dust front on 8 September 2015. Hourly mean PM10 values were close to 8000 µg m−3 and the observed meteorological optical range (visibility was reduced to 300–750 m at Larnaca and Limassol. The visibility observations suggest peak values of the near-surface total suspended particle (TSP extinction coefficients of 6000 Mm−1 and thus TSP mass concentrations of 10 000 µg m−3. The Raman polarization lidar observations mainly indicated a double layer structure of the dust plumes (reaching to about 4 km height, pointing to at least two different dust source regions. Dust particle extinction coefficients (532 nm already exceeded 1000 Mm−1 and the mass concentrations reached 2000 µg m−3 in the elevated dust layers on

  8. Harnessing genomics to improve health in the Eastern Mediterranean Region – an executive course in genomics policy

    Directory of Open Access Journals (Sweden)

    Singer Peter A

    2005-01-01

    Full Text Available Abstract Background While innovations in medicine, science and technology have resulted in improved health and quality of life for many people, the benefits of modern medicine continue to elude millions of people in many parts of the world. To assess the potential of genomics to address health needs in EMR, the World Health Organization's Eastern Mediterranean Regional Office and the University of Toronto Joint Centre for Bioethics jointly organized a Genomics and Public Health Policy Executive Course, held September 20th–23rd, 2003, in Muscat, Oman. The 4-day course was sponsored by WHO-EMRO with additional support from the Canadian Program in Genomics and Global Health. The overall objective of the course was to collectively explore how to best harness genomics to improve health in the region. This article presents the course findings and recommendations for genomics policy in EMR. Methods The course brought together senior representatives from academia, biotechnology companies, regulatory bodies, media, voluntary, and legal organizations to engage in discussion. Topics covered included scientific advances in genomics, followed by innovations in business models, public sector perspectives, ethics, legal issues and national innovation systems. Results A set of recommendations, summarized below, was formulated for the Regional Office, the Member States and for individuals. • Advocacy for genomics and biotechnology for political leadership; • Networking between member states to share information, expertise, training, and regional cooperation in biotechnology; coordination of national surveys for assessment of health biotechnology innovation systems, science capacity, government policies, legislation and regulations, intellectual property policies, private sector activity; • Creation in each member country of an effective National Body on genomics, biotechnology and health to: - formulate national biotechnology strategies - raise

  9. Boundary-Layer Characteristics of Persistent Regional Haze Events and Heavy Haze Days in Eastern China

    Directory of Open Access Journals (Sweden)

    Peng Huaqing

    2016-01-01

    Full Text Available This paper analyzed the surface conditions and boundary-layer climate of regional haze events and heavy haze in southern Jiangsu Province in China. There are 5 types with the surface conditions which are equalized pressure (EQP, the advancing edge of a cold front (ACF, the base of high pressure (BOH, the backside of high pressure (BAH, the inverted trough of low pressure (INT, and saddle pressure (SAP with the haze days. At that time, 4 types are divided with the regional haze events and each of which has a different boundary-layer structure. During heavy haze, the surface mainly experiences EQP, ACF, BOH, BAH, and INT which also have different boundary-layer structures.

  10. A Study of Logistics Development In The Malaysia Eastern Region: A Descriptive Analysis

    Directory of Open Access Journals (Sweden)

    Abdul Aziz Zuraimi

    2013-07-01

    Full Text Available This study investigated the current logistics development in The East Coast Region of Pennisular Malaysia. Logistics development is paramount important to the country in supporting economic and growth and enhancing competitiveness. Malaysia as well as many developing countries are still at the moderate stage in developing logistics systems and often face considerable challenges and constraints to provide efficient and effective logistics service. The respondents were from the different logistics players and there were 41 usable questionnaires were analyzed. This study found that the existing logistics infrastructures at the average level in this region. Amongst the constraints and challenges were professionalism in supporting the development, skill of manpower and financial issues in organization. Albeit all the constraints, most respondents were satisfied with the services rendered by logistics service providers.

  11. The Need for a Regional Security System Multinational Coast Guard Unit in the Eastern Caribbean

    Science.gov (United States)

    2012-06-08

    the teaching staff of Staff Group 11 A (Mr Matt Bonnott, Dr Thomas Huber, LTC Andrew McIntyre) and Mr William Knight for officiating, my oral...assist me on this journey. Finally, to my wife Vonette, son Isaiah , daughter Makayla, my mother Muriel (this one is for you), and my friends (too...for the implementation of a new security risk management mechanism to enhance the security of the RSS sub-region. According to Thomas Norman in the

  12. Regional impacts of expanding gas-fired electric generation in the northeast US and eastern Canada

    International Nuclear Information System (INIS)

    Mitchell, G.

    2002-01-01

    New York, New England, Ontario, Quebec and Canada's Maritime provinces come under the jurisdiction of the Northeast Power Coordinating Committee (NPCC) of the North American Electric Reliability Council (NERC). The objective of this Council is to assist with the coordination of electric supply, as well as transmission planning and reliability for the utilities. The annual ten year forecast of electric supply, demand and fuel sources produced by the NERC formed the basis for the data presented. The deregulation of the electricity market in a few jurisdictions in the region resulted in the break-up of several electric utilities into their core components, namely, generation, distribution and transmission. The generation sector is where the fastest break-up activity is taking place, and merchant energy companies are emerging. Each of these merchant energy companies is competing against the other to effect sales into the wholesale power market through the building of at risk generation plants. The deregulation process is subjected to different processes and time tables depending on each state or province regulations. The construction of new power plants in the region is being driven by the merchant energy companies. They are building low capital cost and highly efficient natural gas combined-cycle base load plants as well as lower cost and moderately efficient natural gas/oil-fired simple-cycle peaking plants. This activity is mainly restricted to the United States, since hydroelectric power, coal and nuclear power are the main presence in Canada. New England experiences summer peaks while Canada has winter peak electric demand. To optimize intra-regional peak generation capacity sharing, there is an opportunity for the electric industry to move gas by wire, and a number of projects are being developed. It is expected that pipeline expansion will be lower in Quebec and Ontario and result in more capacity expansions from the Maritimes combined with intra-regional

  13. Regional variation of flow duration curves in the eastern United States: Process-based analyses of the interaction between climate and landscape properties

    Science.gov (United States)

    Wafa Chouaib; Peter V. Caldwell; Younes Alila

    2018-01-01

    This paper advances the physical understanding of the flow duration curve (FDC) regional variation. It provides a process-based analysis of the interaction between climate and landscape properties to explain disparities in FDC shapes. We used (i) long term measured flow and precipitation data over 73 catchments from the eastern US. (ii) We calibrated the...

  14. Appropriateness of Recommended Agricultural Water-Management Technologies as Perceived by the Personnel of Research and Extension System: A Study in the Eastern Region of India

    Science.gov (United States)

    Ghosh, Souvik; Verma, H. N.; Chandra, Dinesh; Nanda, P.

    2005-01-01

    The key to agricultural development in the eastern region of India, where problems of excess water and water scarcity coexist, is the scientific management of water resources with the adoption of recommended water-management technologies. A vast networking of infrastructure for the development and dissemination of water-management technologies…

  15. Moisture source in the Hyblean Mountains region (south-eastern Sicily, Italy): Evidence from stable isotopes signature

    Energy Technology Data Exchange (ETDEWEB)

    Grassa, Fausto [Istituto Nazionale di Geofisica e Vulcanologia, Sezione di Palermo, Via Ugo La Malfa, 153, 90146 Palermo (Italy)]. E-mail: f.grassa@pa.ingv.it; Favara, Rocco [Istituto Nazionale di Geofisica e Vulcanologia, Sezione di Palermo, Via Ugo La Malfa, 153, 90146 Palermo (Italy); Valenza, Mariano [Dipartimento CFTA, Universita di Palermo, Palermo, Via Archirafi, 36, 90123, Palermo (Italy)

    2006-12-15

    Here the authors present results of an isotope study on precipitation collected during a 2-a period from a rain-gauge network consisting of 6 stations located at different elevations in the Hyblean Mountains (HM) region, in south-eastern Sicily. The slope of the local meteoric water line ({delta}D = 6.50 {delta} {sup 18}O + 9.87) obtained for the region suggests that precipitation is affected by evaporation during rainfall events. The main variations in rainwater isotope composition are due to seasonal effects and elevation. An average {sup 2}H excess value of +21.2 per mille was found for precipitation events less affected by evaporation (i.e. when the rainfall was >65 mm/month). The spatial distribution of O isotope composition of precipitation shows a negative gradient from east and south to the inner areas. The depositional rate of Cl, used as a tracer of the origin of air masses, is highest at the coastal rain-gauges (SR and MRG stations) and lowest on the northern flank of the HM region (SC station). Based on these findings, a model is proposed for the origin of precipitation in the HM region, which assumes that a Mediterranean-derived component is the main source of moisture in the studied area. D/H and {sup 18}O/{sup 16}O ratios of inferred meteoric recharge waters were also compared with the isotope composition of waters collected from the main local springs and wells. The best linear fit of the {delta} {sup 18}O vs {delta}D relationship for Hyblean groundwater is {delta}D = 4.85 {delta} {sup 18}O-2.01. The enrichment of heavy isotopes in Hyblean groundwater is probably due to evaporation occurring after precipitation events or to a recharging contribution from surface waters (lakes or rivers) enriched in heavy isotopes.

  16. Moisture source in the Hyblean Mountains region (south-eastern Sicily, Italy): Evidence from stable isotopes signature

    International Nuclear Information System (INIS)

    Grassa, Fausto; Favara, Rocco; Valenza, Mariano

    2006-01-01

    Here the authors present results of an isotope study on precipitation collected during a 2-a period from a rain-gauge network consisting of 6 stations located at different elevations in the Hyblean Mountains (HM) region, in south-eastern Sicily. The slope of the local meteoric water line (δD = 6.50 δ 18 O + 9.87) obtained for the region suggests that precipitation is affected by evaporation during rainfall events. The main variations in rainwater isotope composition are due to seasonal effects and elevation. An average 2 H excess value of +21.2 per mille was found for precipitation events less affected by evaporation (i.e. when the rainfall was >65 mm/month). The spatial distribution of O isotope composition of precipitation shows a negative gradient from east and south to the inner areas. The depositional rate of Cl, used as a tracer of the origin of air masses, is highest at the coastal rain-gauges (SR and MRG stations) and lowest on the northern flank of the HM region (SC station). Based on these findings, a model is proposed for the origin of precipitation in the HM region, which assumes that a Mediterranean-derived component is the main source of moisture in the studied area. D/H and 18 O/ 16 O ratios of inferred meteoric recharge waters were also compared with the isotope composition of waters collected from the main local springs and wells. The best linear fit of the δ 18 O vs δD relationship for Hyblean groundwater is δD = 4.85 δ 18 O-2.01. The enrichment of heavy isotopes in Hyblean groundwater is probably due to evaporation occurring after precipitation events or to a recharging contribution from surface waters (lakes or rivers) enriched in heavy isotopes

  17. Distribution of arbuscular mycorrhizal fungi associated with different land use systems of Arunachal Pradesh of Eastern Himalayan region.

    Science.gov (United States)

    Bordoloi, A; Nath, P C; Shukla, A K

    2015-10-01

    Arbuscular mycorrhizal fungi are the main component of soil microbial population in most agroecosystems. They forms a close association with more than 80% of the plant species making immobilized mineral nutrients available to the plants in order to sustain normal growth and reproduction. In this study the diversity of mycorrhizal fungi has been examined in seven land use ecosystems of Arunachal Pradesh in Eastern Himalayan region. A total of 24 species of AM fungi belonging to 4 genera viz., Glomus, Scutellospora, Aculospora and Gigaspora were isolated from the soil samples collected from different land use systems. Glomus was the dominant genera and Glomus occulatum was the most abundant species in all the seven land use systems. Total spore number was highly variable among all the land use systems. Species richness was recorded highest in natural forest that maintains a faster nutrient cycle with the highest diversity index. The Jhum fallow land and tea garden has the least number of AM fungal species due to high disturbance of fire and application of fungicides and inorganic fertilizer. Further the plant species composition, particularly the ground vegetation coverage and disturbance level affects the distribution of the AM fungal species. In our study it has been shown that AMF diversity is significantly affected by the land use practices practiced by the people. Hence, the AM fungi isolated from different land use system may be useful in improving the agriculture practices particularly the plantation crops in the region.

  18. Risk Factors and Spatial Clusters of Cryptosporidium Infection among School-Age Children in a Rural Region of Eastern China.

    Science.gov (United States)

    Zheng, Hao; He, Jianfeng; Wang, Li; Zhang, Rong; Ding, Zhen; Hu, Wenbiao

    2018-05-06

    The epidemiological features of Cryptosporidium infection among school-age children in China still remain unclear. Hereby, a cross-sectional study of 1637 children aged 3⁻9 years was designed to investigate the risk factors and spatial clusters of Cryptosporidium infection in a rural region of Eastern China. Stool specimens collected from participants were examined using the auramine-phenol and modified acid-fast staining. Univariable and multivariable analyses were performed to identify the risk factors of Cryptospordium infection. The spatial clusters were analyzed by a discrete Poisson model using SaTScan software. Our results showed that the overall prevalence of Cryptosporidium infection was 11‰ in the research region. At the age of 3⁻6 years (odds ratios (OR) = 3.072, 95% confidence intervals (CI) : 1.001⁻9.427), not washing hands before eating and after defecation (OR = 3.003, 95% CI: 1.060⁻8.511) were recognized as risk factors. Furthermore, a high-risk spatial cluster (relative risk = 4.220, p = 0.025) was identified. These findings call for effective sustainable interventions including family and school-based hygienic education to reduce the prevalence of Cryptosporidium infection. Therefore, an early warning system based spatiotemporal models with risk factors is required to further improve the effectiveness and efficiency of cryptosporidiosis control in the future.

  19. Pattern of occurrence of leukemia at a teaching hospital in eastern region of Nepal - a six year study.

    Science.gov (United States)

    Kulshrestha, R; Sah, S P

    2009-01-01

    Pattern of leukemia is known to vary widely throughout the world. The characterization of distribution patterns of different subtypes of leukemia in Nepal needs further study. We wanted to study the leukemia pattern in our institute. A retrospective study of 196 cases of leukemia, diagnosed at BPKIHS, between January 1997 to December 2002 was done. We analyzed the pattern of leukemia at BPKIHS by morphological subtype, gender, age at diagnosis, time period of diagnosis (seasonality), and geographic distribution. Morphological sub typing showed that 121 cases were of acute leukemia and 75 of chronic leukemia. Chronic myeloid leukemia constituted the single largest group comprising 35.2 % of all cases, followed by acute myeloid leukemia (28.57 %) and acute lymphoid leukemia (19.9 %). Maximum numbers of cases were from the lowlands while least number of cases were from the mountain districts. Results were compared with literature from Nepal and other countries. This is the second series of leukemia from Nepal. The data published in this study reflects the leukemia pattern in the eastern region of Nepal. The pattern and distribution of AML, CML, ALL was similar to that in the developed western countries while the lesser frequency of CLL was similar to that in Southeast Asian region.

  20. Genetic relatedness among indigenous rice varieties in the Eastern Himalayan region based on nucleotide sequences of the Waxy gene.

    Science.gov (United States)

    Choudhury, Baharul I; Khan, Mohammed L; Dayanandan, Selvadurai

    2014-12-29

    Indigenous rice varieties in the Eastern Himalayan region of Northeast India are traditionally classified into sali, boro and jum ecotypes based on geographical locality and the season of cultivation. In this study, we used DNA sequence data from the Waxy (Wx) gene to infer the genetic relatedness among indigenous rice varieties in Northeast India and to assess the genetic distinctiveness of ecotypes. The results of all three analyses (Bayesian, Maximum Parsimony and Neighbor Joining) were congruent and revealed two genetically distinct clusters of rice varieties in the region. The large group comprised several varieties of sali and boro ecotypes, and all agronomically improved varieties. The small group consisted of only traditionally cultivated indigenous rice varieties, which included one boro, few sali and all jum varieties. The fixation index analysis revealed a very low level of differentiation between sali and boro (F(ST) = 0.005), moderate differentiation between sali and jum (F(ST) = 0.108) and high differentiation between jum and boro (F(ST) = 0.230) ecotypes. The genetic relatedness analyses revealed that sali, boro and jum ecotypes are genetically heterogeneous, and the current classification based on cultivation type is not congruent with the genetic background of rice varieties. Indigenous rice varieties chosen from genetically distinct clusters could be used in breeding programs to improve genetic gain through heterosis, while maintaining high genetic diversity.

  1. The finite element model for the propagation of light in scattering media: a direct method for domains with nonscattering regions.

    Science.gov (United States)

    Arridge, S R; Dehghani, H; Schweiger, M; Okada, E

    2000-01-01

    We present a method for handling nonscattering regions within diffusing domains. The method develops from an iterative radiosity-diffusion approach using Green's functions that was computationally slow. Here we present an improved implementation using a finite element method (FEM) that is direct. The fundamental idea is to introduce extra equations into the standard diffusion FEM to represent nondiffusive light propagation across a nonscattering region. By appropriate mesh node ordering the computational time is not much greater than for diffusion alone. We compare results from this method with those from a discrete ordinate transport code, and with Monte Carlo calculations. The agreement is very good, and, in addition, our scheme allows us to easily model time-dependent and frequency domain problems.

  2. Production systems and reproductive performances of Camelus dromedarius in Somali regional state, eastern Ethiopia

    Directory of Open Access Journals (Sweden)

    Simenew Keskes

    2013-12-01

    Full Text Available Across-sectional questionnaire survey and focused group discussions were conducted to characterize camel production systems and to evaluate reproductive performances of camels at their natural pastoralist management systems of Somali region. A total of 100 households were included in the study during the period of October 2012 to March 2013. About 98% of Somali pastoralists preferred camels as their first choice over other livestock species and mainly kept in the society for milk and meat production. The camel management dominating in the study areas of Somali region is traditional nomadic. Camel is one of the most important livestock for Somali pastoralists’ livelihood as a source of milk, meat and draught power. Mature female camels were dominant (54.87% in the camel herd. The ratio of male to female camel was 1:13. Mean age at first calving and calving interval were 62.16±10.44 and 23.28±3.36 months respectively. Age at first calving and calving interval can be minimized to 57±5.52 and 21.84±4.8 months by proper husbandry and health care. The mean lactation length was 11.51±1.91 months. Diseases and predators were reported as the main causes of calf mortality. In the herd dynamic simulation calf mortality rate can be reduced at least to 7% only by preventing predators attack. Diseases (66%, lack of pasture (59% and security (47% were the main constraints in camel production of the study areas. For the better productivity of camels, the major constraints such as disease problems, lack of pasture and tribal conflicts should be mitigated. Proper husbandry and health services can play significant roles in the long term improvement of camel production and productivity of the region.  

  3. Factors Related to the Sexual Behaviors among Youth in Universities Located in the Eastern Region of Thailand.

    Science.gov (United States)

    Thongnopakun, Saowanee; Maharachpong, Nipa; Abdullakasim, Pajaree

    2016-01-01

    Youth is a "crisis period", as it is a transitional period between childhood and adulthood. This period incites the youth to have curiosity, especially to sexual contents. As a result, they have higher risk behavior leading to the percentage of newly HIV infected persons among youth in the eastern region that is proportionally higher. This research aimed to study factors related to sexual health behaviors among youth in universities located in the eastern region of Thailand. This research was a cross-sectional survey research. The data collection process was conducted from June-September 2011. There were 405 informants, who participated in this study. They were students from both government and private universities in the eastern region. The age of the youth was 20-24 years old. The students' field of study varied. The tool of the study was self-answered questionnaires. The quantitative data were analyzed using descriptive statistics and presented as frequency, percentage, average score, deviation standard scale, and it was analyzed by Crude odds ratio. It was found that three-fifths of the youth already had sexual experiences, and more than half did not use condoms during their first-time sex. Regarding sexual behavior, it was found that almost one-fourth of the students did not use condoms at any time when they had sex, and did not negotiate for safer safe when they had sex. The statistical significance was (p = 0.012, Crude OR = 1.65). Youth who already had sex had more chances to have unprotected sex than those who never had sex (p = 0.014, Crude OR = 1.64). Youth who had casual sex partner(s) had more chances to have unprotected sex than youth who did not have casual sex partner(s) (p = 0.026, Crude OR = 1.78). Youth who had little knowledge on AIDS and sexually transmitted diseases would have more chances to have unprotected sex than youth who had high level of knowledge on these topics (p = 0.010, Crude OR = 2.83). Youth who had negative attitudes towards

  4. Population resources of an endangered species Salix lapponum L. in Polesie Lubelskie Region (eastern Poland

    Directory of Open Access Journals (Sweden)

    Magdalena Pogorzelec

    2014-12-01

    Full Text Available This research, carried out in the years 2011–2013, aimed to evaluate Salix lapponum stands in the peat bogs of Polesie Lubelskie Region as well as to determine the condition of the population and the changes that have taken place since the 1950’s. An inventory carried out in 25 stands of S. lapponum known from the literature shows that the number of its stands has decreased by 80% in Polesie Lubelskie Region. In all the confirmed locations, a decrease in population numbers was also found in relation to the data known from the literature since the 1950’s. In the majority of the population locations that were considered to be extinct, there were no significant changes in habitat conditions, and ecological succession and changes in hydrological conditions could have been the cause of habitat changes only at a few sites. In the light of the study, the preservation of the S. lapponum population in Polesie Lubelskie seems to be impossible if appropriate active conservation measures are not taken immediately. Because area-based conservation, which covers most of the habitats of the studied species, does not bring the expected results, the possibility of ex situ conservation and enlargement of the populations existing in the natural environment in peat bog ecosystems in Polesie should be explored.

  5. Determinants of life expectancy in eastern mediterranean region: a health production function.

    Science.gov (United States)

    Bayati, Mohsen; Akbarian, Reza; Kavosi, Zahra

    2013-06-01

    Determinants of health or health production function in health economics literature constitute noticeable issues in health promotion. This study aimed at estimating a health production function for East Mediterranean Region (EMR) based on the Grossman theoretical model. This ecological study was performed using the econometric methods. The panel data model was used in order to determine the relationship between life expectancy and socioeconomic factors. The data for 21 EMR countries between 1995 and 2007 were used. Fixed-effect-model was employed to estimate the parameters based on Hausman test. In estimating the health production function, factors such as income per capita (β=0.05, Pdeterminants of health status, proxied by life expectancy at birth. A notable result was the elasticity of life expectancy with respect to the employment rate and its significance level was different between males (β=0.13, P0.001). In order to improve the health status in EMR countries, health policymakers should focus on the factors which lie outside the healthcare system. These factors are mainly associated with economic growth and development level. Thus, the economic stabilisation policies with the aim of increasing the productivity, economic growth, and reducing unemployment play significant roles in the health status of the people of the region.

  6. Physical culture in life of Eastern-European region students: modern state and prospects of development

    Directory of Open Access Journals (Sweden)

    S.S. Iermakov

    2015-12-01

    Full Text Available Purpose: analysis of researches on physical culture problems among students in countries of Easter-European region (2013-2015. Material: As sources of information we chose data base of Russia, Poland and Ukraine. Besides, we used sites of the most known journals of Easter-European region. When choosing journals we based on rating of Russia (RISC, Poland (Index Copernicus and Ukraine (bibliometryka of Ukrainian science data bases. Results: thematic focus of researches on different physical education, sports and students health aspects was determined. The promising directions of researches are as follows: re-organization of system of students’ physical education; interconnection of life quality and organism’s resistance to environmental impacts; dependence of students’ motor functioning on bad habits’ presence; determination of factors, facilitating motivation for sport games in system of students’ health related trainings; perceiving of life quality by disabled students; competence and professional skillfulness of specialists in physical culture and sports. Conclusions: it is recommended to use new, attractive forms of students’ motor functioning. It is necessary to regulate students’ motor functioning, considering motivation for success and for avoiding failures as well as to increase students’ psycho-physiological stresses’ resistance and to form students’ culture of health.

  7. Transforming p21 ras protein: flexibility in the major variable region linking the catalytic and membrane-anchoring domains

    DEFF Research Database (Denmark)

    Willumsen, B M; Papageorge, A G; Hubbert, N

    1985-01-01

    or increasing it to 50 amino acids has relatively little effect on the capacity of the gene to induce morphological transformation of NIH 3T3 cells. Assays of GTP binding, GTPase and autophosphorylating activities of such mutant v-rasH-encoded proteins synthesized in bacteria indicated that the sequences...... that is required for post-translational processing, membrane localization and transforming activity of the proteins. We have now used the viral oncogene (v-rasH) of Harvey sarcoma virus to study the major variable region by deleting or duplicating parts of the gene. Reducing this region to five amino acids...... that encode these biochemical activities are located upstream from the major variable region. In the context of transformation, we propose that the region of sequence heterogeneity serves principally to connect the N-terminal catalytic domain with amino acids at the C terminus that are required to anchor...

  8. Episodic response project: Wet deposition at watersheds in three regions of the eastern United States

    International Nuclear Information System (INIS)

    Barchet, W.R.

    1991-11-01

    During the period from August 1988 to June 1990, wet-only sampling of precipitation was carried out at three Episodic Response Project sites and at one supplemental site. The three watershed sites are Moss Lake, Biscuit Brook, and Linn Run. The supplemental site was the MAP3S site at Pennsylvania State University that characterizes the central group of northern Appalachian streams. The site operators adhered by varying degrees to the sample collection protocol based on the daily sampling protocol of the MAP3S Precipitation Chemistry Network. Sulfate and nitrate ion together accounted for more than 80% of total anions (in μEq/L) in the precipitation at all sites. Wet deposition of sulfate at Moss Lake, Biscuit Brook, Penn State, and Linn Run averaged 223, 230, 253, and 402 mg/m 2 /month, respectively, whereas nitrate wet deposition averaged 197, 195, 160, and 233 mg/m 2 /month, respectively. Sulfate deposition was a factor of 2 to 4 higher in summer than in winter. The seasonal pattern for nitrate deposition was weak; the seasonal contrast was less than a factor of 2.5 at all sites. The association between the wet deposition and precipitation chemistry at the MAP3S monitoring site and the average for the study watersheds was dependent on the distance between the site and watershed and the intervening terrain. Precipitation chemistry at the monitoring site is representative of that at the ERP study watersheds in the Adirondack and Catskill regions and in the south-western group of watersheds in the Appalachian region. High spatial variability in precipitation amounts makes this assumption weaker for wet deposition. Chemical input to watersheds from dry deposition has not been determined at any site but could range from a factor of 0.3 to 1.0 of the wet deposition. 7 refs., 38 figs., 12 tabs

  9. Chat (Catha edulis): a socio economic crop in Harar Region, Eastern Ethiopia.

    Science.gov (United States)

    Kandari, Laxman S; Yadav, Hiranmai R; Thakur, Ashok K; Kandari, Tripti

    2014-01-01

    Chat (Catha edulis) is an important perennial crop and its leaves are chewed for a stimulating effect. It is widely cultivated in the Ethiopian highlands of Oromia region and is figured as Ethiopia's second largest foreign exchange earner. Its cultivation accounts for about 70% of farmer's income in the study area. The common effect of its consumption leads to insomnia, a condition that the users sometimes try to overcome with sedatives or alcohol. The present study is an attempt to survey and assess the impact of crop on the community. It has been observed to implicate health problems, reduces savings and nutritional standards of the family members. The chat yields in the area ranges from 1500-1800 kg/ha through monoculture. During the study, the average monthly income of the family practicing chat cultivation was from Birr 8, 533.00 to 13, 166.00 kg/ha per year in Baate and Genede cultivating areas. When the average cost per/ha was rupees 60/kg. The present study shows that during the recent past, leaf consumption has increased significantly. Chat growers are not only producers but also traders and consumers. Its consumption has become a widespread habit from secondary schools. Highest number of consumers was found to be among drivers followed by students and shopkeepers. The consumption of the plant is not considered a taboo but on contrary a status symbol in the region. It has no legal or moral implications and is considered as a part of custom and habit of local people. High value cash crop like vegetables and orchard fruits needs to be used as a replacement for chat which could be a regular source of income to farmers. Alternative sources of income for farmers needs to be scientifically worked out and proposed keeping in view the proportion of agricultural land reserved under chat cultivation and to increase the production of food grains being produced.

  10. Strategic positioning of the ERATOSTHENES Research Centre for atmospheric remote sensing research in the Eastern Mediterranean and Middle East region

    Science.gov (United States)

    Mamouri, Rodanthi-Elisavet; Ansmann, Albert; Hadjimitsis, Diofantos G.; Nisantzi, Argyro; Bühl, Johannes; Michaelides, Silas; Seifert, Patric; Engelmann, Ronny; Wandinger, Ulla; Kontoes, Charalampos; Schreier, Gunter; Komodromos, Georgios; Themistocleous, Kyriacos

    2017-10-01

    The aim of this article is to present the importance of a permanent state-of-the-art atmospheric remote sensing ground based station in the region of the Eastern Mediterranean and Middle East (EMME). The ERATOSTHENES Research Centre (ERC) with the vision to become a Centre of Excellence for Earth Surveillance and Space-Based Monitoring of the Environment (EXCELSIOR H2020: Teaming project) already operates (within Phase 1) a fully established EARLINETt-Cloudnet supersite at Limassol, Cyprus, for a period of 2 years, in close collaboration with the German Leibniz Institute for Tropospheric Research (TROPOS), The scientific aspects of this prototype-like field campaign CyCARE (Cyprus Cloud Aerosol and Rain Experiment) - a common initiative between the Cyprus University of Technology (CUT), Limassol and TROPOS- are presented in this paper. Cy-CARE has been designed by TROPOS and CUT to fill a gap in the understanding of aerosol-cloud interaction in one of the key regions of climate change and how precipitation formation is influenced by varying aerosol/pollution and meteorological conditions The guiding questions are: How may rain patterns change in future and what may be the consequences of climate change in arid regions such as EMME. EXCELSIOR is a team effort between CUT (acting as the coordinator), the German Aerospace Centre (DLR), the Institute for Astronomy and Astrophysics Space Applications and Remote Sensing of the National Observatory of Athens (NOA), TROPOS and the Cyprus Department of Electronic Communications of the Ministry of Transport, Communications and Works (DEC-MTCW) who will work together to improve the network structures significantly, resulting in Cyprus being regarded as a cornerstone of a European Network of active remote sensing of the atmosphere.

  11. Gender Role Attitudes among Higher Education Students in a Borderland Central-Eastern European Region called ‘Partium’

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    Hajnalka Fényes

    2014-06-01

    Full Text Available In this paper, we examine the attitudes towards gender roles among higher education students in a borderland Central-Eastern European region. We used the database of ‘The Impact of Tertiary Education on Regional Development’ project (N=602, 2010. We intend to determine what kind of attitudes towards gender roles the students identify themselves with, what affects these attitudes (gender, faculty type, social background of students, locality type, religiosity, and finally what kind of educational policy implications could be relevant concerning our findings. We have used cluster analysis and a logistic regression model, and formulated several hypotheses that were controlled by these methods. Our results show that there are a large number of students who belong to the more traditional attitude cluster in this region, but women more frequently identify themselves with modern gender roles than men do. The faculty-type effect has only been partly detected. We have found that with ‘male-dominated’ majors, both women and men identify themselves with more traditional attitudes and that with ‘female-dominated’ majors all students have more modern attitudes. The effect of social background is contradictory. Those whose parents had larger numbers of books had increased modern attitudes, but the factor ‘regular financial problems in the family’ also increased it. Our next result is that students who live in villages are not more traditional than others, because they live in cities during their studies. Our final result is that churchly religious students think more traditionally regarding gender roles than others do, but those who are religious in their own way do not.

  12. Precipitation isotopes link regional climate patterns to water supply in a tropical mountain forest, eastern Puerto Rico

    Science.gov (United States)

    Scholl, Martha A.; Murphy, Sheila F.

    2014-05-01

    Like many mountainous areas in the tropics, watersheds in the Luquillo Mountains of eastern Puerto Rico have abundant rainfall and stream discharge and provide much of the water supply for the densely populated metropolitan areas nearby. Projected changes in regional temperature and atmospheric dynamics as a result of global warming suggest that water availability will be affected by changes in rainfall patterns. It is essential to understand the relative importance of different weather systems to water supply to determine how changes in rainfall patterns, interacting with geology and vegetation, will affect the water balance. To help determine the links between climate and water availability, stable isotope signatures of precipitation from different weather systems were established to identify those that are most important in maintaining streamflow and groundwater recharge. Precipitation stable isotope values in the Luquillo Mountains had a large range, from fog/cloud water with δ2H, δ18O values as high as +12 ‰, -0.73 ‰ to tropical storm rain with values as low as -127 ‰, -16.8 ‰. Temporal isotope values exhibit a reverse seasonality from those observed in higher latitude continental watersheds, with higher isotopic values in the winter and lower values in the summer. Despite the higher volume of convective and low-pressure system rainfall, stable isotope analyses indicated that under the current rainfall regime, frequent trade -wind orographic showers contribute much of the groundwater recharge and stream base flow. Analysis of rain events using 20 years of 15 -minute resolution data at a mountain station (643 m) showed an increasing trend in rainfall amount, in agreement with increased precipitable water in the atmosphere, but differing from climate model projections of drying in the region. The mean intensity of rain events also showed an increasing trend. The determination of recharge sources from stable isotope tracers indicates that water supply

  13. Molecular epidemiological survey of hemoglobinopathies in the Wuxi region of Jiangsu Province, eastern China.

    Science.gov (United States)

    Lin, Min; Han, Zhi-Jun; Wang, Qian; Zheng, Lei; Wang, Yan; Yang, Hui; Huang, Yue; Lin, Fen; Zhan, Xiao-Fen; Lin, Chun-Ping; Wu, Jiao-Ren; Luo, Zhao-Yun; Liu, Jing-Bo; Yan, Zhi-He; Zheng, Shu-Yan; Zheng, Jia-Kun; Lu, Min; Zhu, Juan-Juan; Xie, Long-Xu; Yang, Li-Ye

    2013-01-01

    In order to determine the prevalence and molecular characterization of hemoglobinopathies in the Wuxi region of Jiangsu Province in the People's Republic of China (PRC), a total of 10,297 healthy people selected from a regional hospital were screened. Hemoglobin (Hb) electrophoresis, complete blood cell (CBC) count, polymerase chain reaction (PCR), DNA sequencing, reverse dot-blot and multiplex ligation-dependent probe amplification (MLPA) were used to detect Hb variants, thalassemias and hereditary persistence of fetal Hb (HPFH). Two thousand and twenty-one adult subjects were screened for thalassemia, five cases were identified as α-thalassemia (α-thal) carriers including three cases of the -α(3.7) (rightward) deletion, one case of the - -(SEA) deletion and one case of β-thal [IVS-II-654 (C>T), (HBB: c.316-197C>T)]. The incidence of Hb variants, thalassemia and HPFH/δβ-thal were 0.136% (14/10,297), 0.25% (5/2021) and 0.0001% (1/10,297), respectively. Eight genotypes of Hb variants were found, including Hb E [β26(B8)Glu→Lys, GAG>AAG; HBB: c.79G>A], Hb J-Bangkok [β56(D7)Gly→Asp (GGC>GAC); HBB; c.170G>A], Hb G-Coushatta [β22(4)Glu→Ala (GAA>GCA); HBB: c.68A>C], Hb Queens [α34(B15)Leu→Arg (CTG>CGG) (α2 or α1); HBA2: c.104T>G (or HBA1)], Hb I [α16(A14)Lys→Glu, AAG>GAG (α1); HBA1: c.49A>G], Hb Beijing [α16(A14)Lys→Asn (AAG>AAC or AAT) (α2 or α1); HBA2: c.51G>C (or HBA1) or 51G>T (or HBA1)], Hb Ube-2 [α68(E17)Asn→Asp (AAC>GAC) (α2 or α1); HBA2: c.205A>G (or HBA1)] and Hb G-Taipei [β22(B4)Glu→Gly (GAA>GGA); HBB: c.68A>G]. A Sicilian δβ(0)-thal, identified for the first time in Asia, was also found in this survey.

  14. Spatiotemporal Patterns of Urbanization in a Developed Region of Eastern Coastal China

    Directory of Open Access Journals (Sweden)

    Jiadan Li

    2014-06-01

    Full Text Available This study presents a practical methodology to monitor the spatiotemporal characteristics of urban expansion in response to rapid urbanization at the provincial scale by integrating remote sensing, urban built-up area boundaries, spatial metrics and spatial regression. Sixty-seven cities were investigated to examine the differences of urbanization intensity, urbanization patterns and urban land use efficiency in conjunction with the identification of socio-economic indicators and planning strategies. Planning proposals to allocate the urbanization intensity among different-sized cities by considering sustainable urban development were also explored. The results showed that the urban area of Zhejiang Province expanded from 31,380 ha in 1980 to 415,184 ha in 2010, indicating that the area of the urban region expanded to more than 13-times the initial urban area. The urban built-up area boundaries became more complex and irregular in shape as the urban area expanded throughout the entire study period. Rapid urban population growth and economic development were identified as significant in stimulating the urban expansion process. However, different-sized cities exhibited marked differences in urban development. Small cities experienced the rapidest urbanization before 2000. Large cities, which are estimated to have the highest urban land use efficiency, had the most dramatic sprawl in urban area at the beginning of the 21st century. Promoting the development of large cities to mega-cities is recommended in Zhejiang Province to ensure sustainable urban development with consideration of land resource preservation.

  15. Multiple Determinants of Anuran Richness and Occurrence in an Agricultural Region in South-Eastern Brazil

    Science.gov (United States)

    Prado, Vitor H. M.; Rossa-Feres, Denise de C.

    2014-04-01

    In agricultural landscapes, studies that identify factors driving species richness and occupancy are important because they can guide farmers to use conservation practices that minimize species loss. In this context, anurans are threatened by habitat loss because they depend on the characteristics of both local water bodies and adjacent landscapes. We used a model selection approach to evaluate the influence of local and landscape variables in determining anuran species richness and occurrence in 40 freshwater bodies in a heavily deforested region of semideciduous Atlantic Forest in southeastern Brazil. Our aim was to develop recommendations for conservation of anuran communities in rural areas. Pond hydroperiod and area were the most important variables for explaining anuran species richness and occupancy, with greatest species richness being found in water bodies with intermediate hydroperiod and area. Other important variables that reflected individual species occupancies were the number of vegetation types and pond isolation. In addition, recent studies evidenced that water bodies near forest fragments have higher anuran abundance or diversity. In conclusion, we suggest the maintenance of semi-permanent ponds, isolated from large rivers or reservoirs and near forest fragments, as an effective strategy to conserve anuran fauna in agricultural landscapes of southeastern Brazil. Brazilian government requires the maintenance of forests as legal reserve in each farm, and farmers need to maintain ponds as drinking water for cattle or crop irrigation. For this reason, the guidelines suggested in the present study can be easily adopted, without additional costs to rural productivity.

  16. Regional inventory of karst activity in the Valley and Ridge Province, eastern Tennessee: Phase 1

    International Nuclear Information System (INIS)

    Newton, J.G.; Tanner, J.M.

    1987-09-01

    A data collection form was developed for use in compiling information in the inventory. Information sources included files on subsidence, state and county highway departments, county agents and executives, soil conservation service representative, etc. Data obtained included location, date of occurrence, number of subsidence features at the reported site, size, topographic setting, geologic setting, and probable causative factors. The regional inventory obtained information on over 300 historic subsidence events at more than 200 sites in East Tennessee. Areas having the greatest areal density of active subsidence include Hamblen, Jefferson, and Loudon Counties. Reported subsidence events occurred between 1945 and 1986. The Knox Group dolomites account for about two-thirds of all reported sinkholes in the inventory. Most of the karst activity occurs in valleys or flat areas. In cases where causative factors could be established, the combination of surface water drainage alteration or impoundment combined with soil disturbance associated with construction activity were most often precursors to subsidence. 54 refs., 10 figs., 4 tabs

  17. Identification of regions involved in substrate binding and dimer stabilization within the central domains of yeast Hsp40 Sis1.

    Directory of Open Access Journals (Sweden)

    Júlio C Borges

    Full Text Available Protein folding, refolding and degradation are essential for cellular life and are regulated by protein homeostatic processes such those that involve the molecular chaperone DnaK/Hsp70 and its co-chaperone DnaJ. Hsp70 action is initiated when proteins from the DnaJ family bind an unfolded protein for delivery purposes. In eukaryotes, the DnaJ family can be divided into two main groups, Type I and Type II, represented by yeast cytosolic Ydj1 and Sis1, respectively. Although sharing some unique features both members of the DnaJ family, Ydj1 and Sis1 are structurally and functionally distinct as deemed by previous studies, including the observation that their central domains carry the structural and functional information even in switched chimeras. In this study, we combined several biophysical tools for evaluating the stability of Sis1 and mutants that had the central domains (named Gly/Met rich domain and C-terminal Domain I deleted or switched to those of Ydj1 to gain insight into the role of these regions in the structure and function of Sis1. The mutants retained some functions similar to full length wild-type Sis1, however they were defective in others. We found that: 1 Sis1 unfolds in at least two steps as follows: folded dimer to partially folded monomer and then to an unfolded monomer. 2 The Gly/Met rich domain had intrinsically disordered characteristics and its deletion had no effect on the conformational stability of the protein. 3 The deletion of the C-terminal Domain I perturbed the stability of the dimer. 4 Exchanging the central domains perturbed the conformational stability of the protein. Altogether, our results suggest the existence of two similar subdomains in the C-terminal domain of DnaJ that could be important for stabilizing each other in order to maintain a folded substrate-binding site as well as the dimeric state of the protein.

  18. Prevalence and determinants of common mental illness among adult residents of Harari Regional State, Eastern Ethiopia

    Science.gov (United States)

    Hunduma, Gari; Girma, Mulugeta; Digaffe, Tesfaye; Weldegebreal, Fitsum; Tola, Assefa

    2017-01-01

    Introduction Common mental disorders include depression, anxiety and somatoform disorders are a public health problem in developed as well as developing countries. It represents a psychiatric morbidity with significant prevalence, affecting all stages of life and cause suffering to the individuals, their family and communities. Despite this fact, little information about the prevalence of common mental illness is available from low and middle-income countries including Ethiopia. The aim of this study was to determine the magnitude of common mental disorders and its associated factors among adult residents of Harari Region. Methods Comparative cross-sectional, quantitative community-based survey was conducted From February 1, 2016 to March 30, 2016 in Harari Regional State using multi-stage sampling technique. A total of 968 residents was selected using two stage sampling technique. Of this 901 were participated in the study. Validated and Pretested Self reported questionnaire (SQR_20) was used to determine the maginitude of common mental disorders. Data was entered and analyzed using Epi-info version 3.5.1 and SPSS-17 for windows statistical packages. Univirate, Bi-variate and multivariate logistic regression analysis with 95% CI was employed in order to infer associations. Results The prevalence of common mental illnesses among adults in our study area was 14.9%. The most common neurotic symptoms in this study were often head ache (23.2%), sleep badly (16%) and poor appetite (13.8%). Substance use like Khat chewing (48.2%), tobacco use (38.2%) and alcohol use (10.5%) was highly prevalent health problem among study participant. In multivariate logistic regression analysis, respondents age between 25-34 years, 35-44 years, 45-54 years and above 55years were 6.4 times (AOR 6.377; 95% CI: 2.280-17.835), 5.9 times (AOR 5.900; 95% CI: 2.243-14.859), 5.6 times (AOR 5.648; 95% CI: 2.200-14.50) and 4.1 times (AOR 4.110; 95% CI: 1.363-12.393) more likely having common

  19. Process- and Domain-Specificity in Regions Engaged for Face Processing: An fMRI Study of Perceptual Differentiation

    Science.gov (United States)

    Collins, Heather R.; Zhu, Xun; Bhatt, Ramesh S.; Clark, Jonathan D.; Joseph, Jane E.

    2015-01-01

    The degree to which face-specific brain regions are specialized for different kinds of perceptual processing is debated. The present study parametrically varied demands on featural, first-order configural or second-order configural processing of faces and houses in a perceptual matching task to determine the extent to which the process of perceptual differentiation was selective for faces regardless of processing type (domain-specific account), specialized for specific types of perceptual processing regardless of category (process-specific account), engaged in category-optimized processing (i.e., configural face processing or featural house processing) or reflected generalized perceptual differentiation (i.e. differentiation that crosses category and processing type boundaries). Regions of interest were identified in a separate localizer run or with a similarity regressor in the face-matching runs. The predominant principle accounting for fMRI signal modulation in most regions was generalized perceptual differentiation. Nearly all regions showed perceptual differentiation for both faces and houses for more than one processing type, even if the region was identified as face-preferential in the localizer run. Consistent with process-specificity, some regions showed perceptual differentiation for first-order processing of faces and houses (right fusiform face area and occipito-temporal cortex, and right lateral occipital complex), but not for featural or second-order processing. Somewhat consistent with domain-specificity, the right inferior frontal gyrus showed perceptual differentiation only for faces in the featural matching task. The present findings demonstrate that the majority of regions involved in perceptual differentiation of faces are also involved in differentiation of other visually homogenous categories. PMID:22849402

  20. Contracting but not without caution: experience with outsourcing of health services in countries of the Eastern Mediterranean Region.

    Science.gov (United States)

    Siddiqi, Sameen; Masud, Tayyeb Imran; Sabri, Belgacem

    2006-11-01

    The public sector in developing countries is increasingly contracting with the non-state sector to improve access, efficiency and quality of health services. We conducted a multicountry study to assess the range of health services contracted out, the process of contracting and its influencing factors in ten countries of the Eastern Mediterranean Region: Afghanistan, Bahrain, Egypt, Islamic Republic of Iran, Jordan, Lebanon, Morocco, Pakistan, the Syrian Arab Republic and Tunisia. Our results showed that Afghanistan, Egypt, Islamic Republic of Iran and Pakistan had experience with outsourcing of primary care services; Jordan, Lebanon and Tunisia extensively contracted out hospital and ambulatory care services; while Bahrain, Morocco and the Syrian Arab Republic outsourced mainly non-clinical services. The interest of the non-state sector in contracting was to secure a regular source of revenue and gain enhanced recognition and credibility. While most countries promoted contracting with the private sector, the legal and bureaucratic support in countries varied with the duration of experience with contracting. The inherent risks evident in the contracting process were reliance on donor funds, limited number of providers in rural areas, parties with vested interests gaining control over the contracting process, as well as poor monitoring and evaluation mechanisms. Contracting provides the opportunity to have greater control over private providers in countries with poor regulatory capacity, and if used judiciously can improve health system performance.

  1. Ecological prevalence, genetic diversity and epidemiological aspects of Salmonella isolated from tomato agricultural regions of the Virginia Eastern Shore

    Directory of Open Access Journals (Sweden)

    Rebecca L. Bell

    2015-05-01

    Full Text Available Virginia is the third largest producer of fresh-market tomatoes in the United States. Tomatoes grown along the eastern shore of Virginia are implicated almost yearly in Salmonella illnesses. Traceback implicates contamination occurring in the pre-harvest environment. To get a better understanding of the ecological niches of Salmonella in the tomato agricultural environment, a two-year study was undertaken at a regional agricultural research farm in Virginia. Environmental samples, including tomato (fruit, blossoms and leaves, irrigation water, surface water and sediment, were collected over the growing season. These samples were analyzed for the presence of Salmonella using modified FDA-BAM methods. Molecular assays were used to screen the samples. Over 1500 samples were tested. Seventy-five samples tested positive for Salmonella yielding over 230 isolates. The most commonly isolated serovars were S. Newport and S. Javiana with pulsed-field gel electrophoresis yielding 39 different patterns. Genetic diversity was further underscored among many other serotypes, which showed multiple PFGE subtypes. Whole genome sequencing of several S. Newport isolates collected in 2010 compared to clinical isolates associated with tomato consumption showed very few single nucleotide differences between environmental isolates and clinical isolates suggesting a source link to Salmonella contaminated tomatoes. Nearly all isolates collected during two growing seasons of surveillance were obtained from surface water and sediment sources pointing to these sites as long-term reservoirs for persistent and endemic contamination of this environment.

  2. Hydration kinetics of some durum and bread wheat varieties grown in south-eastern region of turkey

    International Nuclear Information System (INIS)

    Yildirm, A.

    2017-01-01

    Hydration kinetics of wheat varieties grown in South-Eastern Region of Turkey, covering a temperature range from 25 to 50 degree C was examined. Peleg's model together with Arrhenius relationship were successfully used to evaluate water uptake of some Durum (Local names; Zenit and BurgosBurgos) and Bread (Local names; Dariyel and Karatopak) wheat varieties during soaking at a temperature range of 25-50 degree C. Model was found to be suitable for describing the soaking behaviour of wheat kernels with a coefficient of determination (R2) and Root mean square error (RMSE) greater than 0.9805, and less than 0.051, respectively. The Peleg rate and capacity constants, K1 and K2, were affected by temperature and wheat varieties. Activation energy values of Zenit, BurgosBurgos, Dariyel and Karatopak wheats were found as 39.94, 38.03, 36.25 and 29.54 kJ mol-1, respectively. Zenit wheat was the least hydrated while Karatopak was the most hydrated one due to kernel size and protein content. General equations to describe the water uptake of wheat varieties as a function of soaking time, temperature and initial moisture content were developed. These derived equations can be used for wheat operations such as tempering, mixing, knedding etc. (author)

  3. HYPODONTIA OF PERMANENT TEETH IN A GROUP OF YOUNG PATIENTS FROM THE NORTH‐EASTERN REGION OF ROMANIA

    Directory of Open Access Journals (Sweden)

    Georgeta ZEGAN

    2013-06-01

    Full Text Available The present study deals with the statistical evaluation of the number of congenitally missing teeth, of the affected dental groups, of the clinical forms and of hypodontia topography, performed on a group of patients from the North‐Eastern region of Romania, examined in the Ambu‐ latory of the “Sf. Spiridon” Universitary Emergency Hos‐ pital of Iaşi, between 1990‐2012. 111 patients (51 boys and 60 girls, with ages between 5 and 28 years, have been dia‐ gnosed with hypodontia of the permanent teeth (third molars excepted, by interview and by clinical and orto‐ pantomographic examinations. Statistical analysis made use of a SPSS 20.0 software. Four categories of hypodontia were discovered on the congenitally missing teeth, a high prevalence of the premolar (mandibular and maxillary and maxillary incisor groups, as well as the predominant presence of the mono‐ and unidental clinical forms of hypodontia. Hypodontia was localized both unilaterally and bilaterally, on the four dental quadrants. Statistically significant correlations have been established among the number of teeth, the dental groups with agenesis and the clinical forms of hypodontia (p=0.000.

  4. Contracting but not without caution: experience with outsourcing of health services in countries of the Eastern Mediterranean Region.

    Science.gov (United States)

    Siddiqi, Sameen; Masud, Tayyeb Imran; Sabri, Belgacem

    2006-01-01

    The public sector in developing countries is increasingly contracting with the non-state sector to improve access, efficiency and quality of health services. We conducted a multicountry study to assess the range of health services contracted out, the process of contracting and its influencing factors in ten countries of the Eastern Mediterranean Region: Afghanistan, Bahrain, Egypt, Islamic Republic of Iran, Jordan, Lebanon, Morocco, Pakistan, the Syrian Arab Republic and Tunisia. Our results showed that Afghanistan, Egypt, Islamic Republic of Iran and Pakistan had experience with outsourcing of primary care services; Jordan, Lebanon and Tunisia extensively contracted out hospital and ambulatory care services; while Bahrain, Morocco and the Syrian Arab Republic outsourced mainly non-clinical services. The interest of the non-state sector in contracting was to secure a regular source of revenue and gain enhanced recognition and credibility. While most countries promoted contracting with the private sector, the legal and bureaucratic support in countries varied with the duration of experience with contracting. The inherent risks evident in the contracting process were reliance on donor funds, limited number of providers in rural areas, parties with vested interests gaining control over the contracting process, as well as poor monitoring and evaluation mechanisms. Contracting provides the opportunity to have greater control over private providers in countries with poor regulatory capacity, and if used judiciously can improve health system performance. PMID:17143460

  5. Factors Affecting Farmers’ Decision to Enter Agricultural Cooperatives Using Random Utility Model in the South Eastern Anatolian Region of Turkey

    Directory of Open Access Journals (Sweden)

    Bahri Karlı

    2006-10-01

    Full Text Available Farmers’ decision and perceptions to be a member of agricultural cooperatives in the South Eastern Anatolian Region were investigated. Factors affecting the probability of joining the agricultural cooperatives were determined using binary logit model. The model released that most of variables such as education, high communication, log of gross income, farm size, medium and high technology variables play important roles in determining the probability of entrance. Small farmers are likely expected to join the agricultural cooperatives than the wealthier farmers are. Small farmers may wish to benefit cash at hand, input subsidies, and services provided by the agricultural cooperatives since the risks associated with intensive high-returning crops are high. Some important factors playing pole role in abstention of farmers towards agricultural cooperatives are gross income and some social status variables. In addition, conservative or orthodox farmers are less likely to join agricultural cooperatives than moderate farmers are. We also found that the direct government farm credit programs mainly should be objected to providing farmers to better access to capital markets and creating the opportunity to use with allocation of capital inputs via using modern technology.

  6. The in-situ testing of high efficiency particulate filters in the CEGB south eastern region nuclear power stations

    International Nuclear Information System (INIS)

    Powell, A.W.; Wilkinson, B.A.

    1977-01-01

    High efficiency air filters are installed in the CEGB's Nuclear Power Stations to prevent discharge of radioactive material to the environment should the ventilation air become contaminated. The Board has determined that these filter units should be tested in-situ to ensure that the stringent design specifications are met. This paper describes the rig work comparing the British Standard method using sodium chloride aerosol with other test methods, such as Dioctyl Phthalate, naturally occurring dust aerosols and artificially produced condensation nuclei. This work led to the development of an in-situ test method using condensation nuclei and a Pollak-Nolan nucleus counter. The advantages and disadvantages of this method over other methods for in-situ testing is discussed. The test method has been used in the South Eastern Region for several years and considerable experience has been gained in its use on a wide variety of filter systems. The method adopted for each system is detailed including the injection, sampling and interpretation of the results obtained. Numerous faults and difficulties have been highlighted from the design, installation and filter changing aspects

  7. Serum Concentrations of Selected Heavy Metals in Patients with Alcoholic Liver Cirrhosis from the Lublin Region in Eastern Poland

    Directory of Open Access Journals (Sweden)

    Andrzej Prystupa

    2016-06-01

    Full Text Available According to the WHO report, alcohol is the third most significant health risk factor for the global population. There are contrary reports about heavy metals concentrations in patients with alcoholic liver cirrhosis. The aim of this study was to investigate serum concentrations of selected heavy metals in patients with alcoholic liver cirrhosis living in the eastern part of Poland according to cirrhosis stage. The participants came from various hospitals of the Lublin region were enrolled. The study group included 46 male and 16 female patients. The control group consisted of 18 healthy individuals without liver disease. High Performance Ion Chromatography was used to determine the concentrations of metal ions (Cd, Zn, Cu, Ni, Co, Mn, and Pb in serum samples. The concentrations of copper, zinc, nickel, and cobalt were found to be significantly lower in patients with alcoholic liver cirrhosis compared to the control group. The serum concentration of cadmium was significantly higher in patients with advanced alcoholic liver cirrhosis compared to the control group. We hypothesize that disorders of metabolism of heavy metals seem to be the outcome of impaired digestion and absorption, which are common in cirrhosis, improper diet, environmental and occupational exposure.

  8. Characterization of breeding habitats for black and surf scoters in the eastern boreal forest and subarctic regions of Canada

    Science.gov (United States)

    Perry, M.C.; Kidwell, D.M.; Wells, A.M.; Lohnes, E.J.R.; Osenton, P.C.; Altmann, S.H.; Hanson, Alan; Kerekes, Joseph; Paquet, Julie

    2006-01-01

    We analyzed characteristics of wetland habitats used by breeding black scoters (Melanitta nigra) and surf scoters (M. perspicillata) in the eastern boreal forest and subarctic regions of Canada based on satellite telemetry data collected in the spring and summer. During 2002 and 2004, nine black scoters (four males, five females) were tracked to breeding areas in Quebec, Manitoba, and Northwest Territories. In addition, in 2001?04, seven surf scoters (three males, four females) were tracked to breeding areas in Labrador, Quebec, Northwest Territories, and Nunavut. Based on satellite telemetry data, locations of black and surf scoters in breeding areas were not significantly different in regard to latitude and longitude. Presumed breeding areas were manually plotted on topographic maps and percent cover type and water were estimated. Breeding habitat of black scoters was significantly different than that for surf scoters, with black scoters mainly using open (tundra) areas (44%) and surf scoters using mainly forest areas (66%). Surf scoters presumed breeding areas were at significantly higher elevations than areas used by black scoters. Some breeding areas were associated with islands, but the role of islands for breeding areas is equivocal. These results aid in the identification of potentially critical breeding areas and provide a baseline classification of breeding habitats used by these two species.

  9. The declining rates of hepatitis B carriage among adolescents and young people in the Eastern region of Saudi Arabia

    Science.gov (United States)

    Al-Jubran, Khalid. M.; Al-Dossary, Mohamed. A.; Elsafi, Salah H.

    2016-01-01

    Objectives: To study age specific rates of hepatitis B virus (HBV) carriage in the eastern region of Saudi Arabia following a 24 year immunization program. Methods: Hepatitis B surveillance data between January 2004 and December 2013 were analyzed in a retrospective study, which included 24,504,914 patients. Seropositive cases of hepatitis B were reported by laboratory personnel as part of various investigations. Hepatitis B cases including acute and chronic carriers were identified upon serological positivity of hepatitis B surface antigen (HBsAg). Results: The study shows that the overall prevalence rate decreased from 18.8 to 9.9/100,000 population between 2004 and 2013 (p=0.01). It was also found that the prevalence rate increased with age. For instance, the highest prevalence of hepatitis B was seen among patients >15 years of age and the lowest was seen among children 0.05). Another significant reduction in the prevalence rate occurred among age groups 5-14 years old (p=0.00). An insignificant decrease in the rate by 43% was also seen among older patients of 15-44 years old and 35% in >45 years old. The overall prevalence of hepatitis B is significantly higher in men than in women (p=0.00). Conclusion: There is a particular decreased trend in the prevalence of HBV infection in different age groups over a decade of surveillance following more than 20 years of the universal HBV vaccination program. PMID:27464863

  10. Multi-ensemble regional simulation of Indian monsoon during contrasting rainfall years: role of convective schemes and nested domain

    Science.gov (United States)

    Devanand, Anjana; Ghosh, Subimal; Paul, Supantha; Karmakar, Subhankar; Niyogi, Dev

    2018-06-01

    Regional simulations of the seasonal Indian summer monsoon rainfall (ISMR) require an understanding of the model sensitivities to physics and resolution, and its effect on the model uncertainties. It is also important to quantify the added value in the simulated sub-regional precipitation characteristics by a regional climate model (RCM), when compared to coarse resolution rainfall products. This study presents regional model simulations of ISMR at seasonal scale using the Weather Research and Forecasting (WRF) model with the synoptic scale forcing from ERA-interim reanalysis, for three contrasting monsoon seasons, 1994 (excess), 2002 (deficit) and 2010 (normal). Impact of four cumulus schemes, viz., Kain-Fritsch (KF), Betts-Janjić-Miller, Grell 3D and modified Kain-Fritsch (KFm), and two micro physical parameterization schemes, viz., WRF Single Moment Class 5 scheme and Lin et al. scheme (LIN), with eight different possible combinations are analyzed. The impact of spectral nudging on model sensitivity is also studied. In WRF simulations using spectral nudging, improvement in model rainfall appears to be consistent in regions with topographic variability such as Central Northeast and Konkan Western Ghat sub-regions. However the results are also dependent on choice of cumulus scheme used, with KF and KFm providing relatively good performance and the eight member ensemble mean showing better results for these sub-regions. There is no consistent improvement noted in Northeast and Peninsular Indian monsoon regions. Results indicate that the regional simulations using nested domains can provide some improvements on ISMR simulations. Spectral nudging is found to improve upon the model simulations in terms of reducing the intra ensemble spread and hence the uncertainty in the model simulated precipitation. The results provide important insights regarding the need for further improvements in the regional climate simulations of ISMR for various sub-regions and contribute

  11. Multi-ensemble regional simulation of Indian monsoon during contrasting rainfall years: role of convective schemes and nested domain

    Science.gov (United States)

    Devanand, Anjana; Ghosh, Subimal; Paul, Supantha; Karmakar, Subhankar; Niyogi, Dev

    2017-08-01

    Regional simulations of the seasonal Indian summer monsoon rainfall (ISMR) require an understanding of the model sensitivities to physics and resolution, and its effect on the model uncertainties. It is also important to quantify the added value in the simulated sub-regional precipitation characteristics by a regional climate model (RCM), when compared to coarse resolution rainfall products. This study presents regional model simulations of ISMR at seasonal scale using the Weather Research and Forecasting (WRF) model with the synoptic scale forcing from ERA-interim reanalysis, for three contrasting monsoon seasons, 1994 (excess), 2002 (deficit) and 2010 (normal). Impact of four cumulus schemes, viz., Kain-Fritsch (KF), Betts-Janjić-Miller, Grell 3D and modified Kain-Fritsch (KFm), and two micro physical parameterization schemes, viz., WRF Single Moment Class 5 scheme and Lin et al. scheme (LIN), with eight different possible combinations are analyzed. The impact of spectral nudging on model sensitivity is also studied. In WRF simulations using spectral nudging, improvement in model rainfall appears to be consistent in regions with topographic variability such as Central Northeast and Konkan Western Ghat sub-regions. However the results are also dependent on choice of cumulus scheme used, with KF and KFm providing relatively good performance and the eight member ensemble mean showing better results for these sub-regions. There is no consistent improvement noted in Northeast and Peninsular Indian monsoon regions. Results indicate that the regional simulations using nested domains can provide some improvements on ISMR simulations. Spectral nudging is found to improve upon the model simulations in terms of reducing the intra ensemble spread and hence the uncertainty in the model simulated precipitation. The results provide important insights regarding the need for further improvements in the regional climate simulations of ISMR for various sub-regions and contribute

  12. Meteorological conditions during a severe, prolonged regional heavy air pollution episode in eastern China from December 2016 to January 2017

    Science.gov (United States)

    Deng, Xueliang; Cao, Weihua; Huo, Yanfeng; Yang, Guanying; Yu, Caixia; He, Dongyan; Deng, Weitao; Fu, Wei; Ding, Heming; Zhai, Jing; Cheng, Long; Zhao, Xuhui

    2018-03-01

    A severe, prolonged and harmful regional heavy air pollution episode occurred in eastern China from December 2016 to January 2017. In this paper, the pollutant characteristics and the meteorological formation mechanism of this pollution event, including climate anomalies, surface weather conditions, planetary boundary layer structure and large-scale circulation features, were analysed based on observational pollution data, surface meteorological data, sounding data and ERA-Interim reanalysis data. The results are as follows. (1) Five pollution stages were identified in eastern China. The two most severe episodes occurred from December 27, 2016 to January 4, 2017 and from January 8 to 12 2017. During these two pollution episodes, fine mode particles were major contributors, and hourly PM2.5 concentrations often exceeded 150 μg/m3, reaching a maximum of 333 μg/m3 at Fuyang station. Gaseous pollutants were transformed into secondary aerosols through heterogeneous reactions on the surface of PM2.5. (2) Compared with the same period over the years 2000-2016, 2017 presented meteorological field climate anomalies in conjunction with unfavourable surface conditions (weak winds, high relative humidity, fewer hours of sunshine, high cloud cover) and adverse atmospheric circulation (weak East Asian winter monsoon and an abnormal geopotential height of 500 hPa), which caused poorer visibility in 2017 than in the other analysed years. (3) During the development of heavy pollution event, unfavourable surface weather conditions, including poorer visibility, weaker pressure, higher relative humidity, lower wind speed with unfavourable wind direction and less precipitation suppressed the horizontal diffusion ability of air pollutants. Furthermore, the unfavourable structure of the atmospheric boundary layer was the key cause of the rapid PM2.5 increase. The deep, strong temperature inversion layer and weak vertical wind velocity could have suppressed vertical motion and enhanced

  13. Insights on organic aerosol aging and the influence of coal combustion at a regional receptor site of central eastern China

    Directory of Open Access Journals (Sweden)

    W. W. Hu

    2013-10-01

    Full Text Available In order to understand the aging and processing of organic aerosols (OA, an intensive field campaign (Campaign of Air Pollution at Typical Coastal Areas IN Eastern China, CAPTAIN was conducted March–April at a receptor site (a Changdao island in central eastern China. Multiple fast aerosol and gas measurement instruments were used during the campaign, including a high resolution time-of-flight aerosol mass spectrometer (HR-ToF-AMS that was applied to measure mass concentrations and non-refractory chemical components of submicron particles (PM1nr. The average mass concentration of PM1(PM1nr+black carbon was 47 ± 36 μg m−3 during the campaign and showed distinct variation, depending on back trajectories and their overlap with source regions. Organic aerosol (OA is the largest component of PM1 (30%, followed by nitrate (28%, sulfate (19%, ammonium (15%, black carbon (6%, and chloride (3%. Four OA components were resolved by positive matrix factorization (PMF of the high-resolution spectra, including low-volatility oxygenated organic aerosol (LV-OOA, semi-volatile oxygenated OA (SV-OOA, hydrocarbon-like OA (HOA and a coal combustion OA (CCOA. The mass spectrum of CCOA had high abundance of fragments from polycyclic aromatic hydrocarbons (PAHs (m/z 128, 152, 178, etc.. The average atomic ratio of oxygen to carbon in OA (O / C at Changdao was 0.59, which is comparable to other field studies reported at locations downwind of large pollution sources, indicating the oxidized nature of most OA during the campaign. The evolution of OA elemental composition in the van Krevelen diagram (H / C vs. O / C showed a slope of −0.63; however, the OA influenced by coal combustion exhibits a completely different evolution that appears dominated by physical mixing. The aging of organic aerosols vs. photochemical age was investigated. It was shown that OA / ΔCO, as well as LV-OOA / ΔCO and SV-OOA / ΔCO, positively correlated with photochemical age. LV

  14. Regional difference of the start time of the recent warming in Eastern China: prompted by a 165-year temperature record deduced from tree rings in the Dabie Mountains

    Science.gov (United States)

    Cai, Qiufang; Liu, Yu; Duan, Bingchuang; Sun, Changfeng

    2018-03-01

    Tree-ring studies from tropical to subtropical regions are rarer than that from extratropical regions, which greatly limit our understanding of some critical climate change issues. Based on the tree-ring-width chronology of samples collected from the Dabie Mountains, we reconstructed the April-June mean temperature for this region with an explained variance of 46.8%. Five cold (1861-1869, 1889-1899, 1913-1920, 1936-1942 and 1952-1990) and three warm (1870-1888, 1922-1934 and 2000-2005) periods were identified in the reconstruction. The reconstruction not only agreed well with the instrumental records in and around the study area, but also showed good resemblance to previous temperature reconstructions from nearby regions, indicating its spatial and temporal representativeness of the temperature variation in the central part of eastern China. Although no secular warming trend was found, the warming trend since 1970 was unambiguous in the Dabie Mountains (0.064 °C/year). Further temperature comparison indicated that the start time of the recent warming in eastern China was regional different. It delayed gradually from north to south, starting at least around 1940 AD in the north part, around 1970 AD in the central part and around 1980s in the south part. This work enriches the high-resolution temperature reconstructions in eastern China. We expect that climate warming in the future would promote the radial growth of alpine Pinus taiwanensis in the subtropical areas of China, therefore promote the carbon capture and carbon storage in the Pinus taiwanensis forest. It also helps to clarify the regional characteristic of recent warming in eastern China.

  15. Constraints to applying systems thinking concepts in health systems: A regional perspective from surveying stakeholders in Eastern Mediterranean countries.

    Science.gov (United States)

    El-Jardali, Fadi; Adam, Taghreed; Ataya, Nour; Jamal, Diana; Jaafar, Maha

    2014-12-01

    Systems Thinking (ST) has recently been promoted as an important approach to health systems strengthening. However, ST is not common practice, particularly in Low- and Middle-Income Countries (LMICs). This paper seeks to explore the barriers that may hinder its application in the Eastern Mediterranean Region (EMR) and possible strategies to mitigate them. A survey consisting of open-ended questions was conducted with a purposive sample of health policy-makers such as senior officials from the Ministry of Health (MoH), researchers, and other stakeholders such as civil society groups and professional associations from ten countries in the region. A total of 62 respondents participated in the study. Thematic analysis was conducted. There was strong recognition of the relevance and usefulness of ST to health systems policy-making and research, although misconceptions about what ST means were also identified. Experience with applying ST was very limited. Approaches to designing health policies in the EMR were perceived as reactive and fragmented (66%). Commonly perceived constraints to application of ST were: a perceived notion of its costliness combined with lack of the necessary funding to operationalize it (53%), competing political interests and lack of government accountability (50%), lack of awareness about relevance and value (47%), limited capacity to apply it (45%), and difficulty in coordinating and managing stakeholders (39%). While several strategies have been proposed to mitigate most of these constraints, they emphasized the importance of political endorsement and adoption of ST at the leadership level, together with building the necessary capacity to apply it and apply the learning in research and practice.

  16. Development of a hydrogeological conceptual wetland model in the data-scarce north-eastern region of Kilombero Valley, Tanzania

    Science.gov (United States)

    Burghof, Sonja; Gabiri, Geofrey; Stumpp, Christine; Chesnaux, Romain; Reichert, Barbara

    2018-02-01

    Understanding groundwater/surface-water interactions in wetlands is crucial because wetlands provide not only a high potential for agricultural production, but also sensitive and valuable ecosystems. This is especially true for the Kilombero floodplain wetland in Tanzania, which represents a data-scarce region in terms of hydrological and hydrogeological data. A comprehensive approach combining hydrogeological with tracer-based assessments was conducted, in order to develop a conceptual hydrogeological wetland model of the area around the city of Ifakara in the north-eastern region of Kilombero catchment. Within the study site, a heterogeneous porous aquifer, with a range of hydraulic conductivities, is underlain by a fractured-rock aquifer. Groundwater chemistry is mainly influenced by silicate weathering and depends on groundwater residence times related to the hydraulic conductivities of the porous aquifer. Groundwater flows from the hillside to the river during most of the year. While floodwater close to the river is mainly derived from overbank flow of the river, floodwater at a greater distance from the river mainly originates from precipitation and groundwater discharge. Evaporation effects in floodwater increase with increasing distance from the river. In general, the contribution of flood and stream water to groundwater recharge is negligible. In terms of an intensification of agricultural activities in the wetland, several conclusions can be drawn from the conceptual model. Results of this study are valuable as a base for further research related to groundwater/surface-water interactions and the conceptual model can be used in the future to set up numerical flow and transport models.

  17. Single particle analysis of eastern Mediterranean aerosol particles: Influence of the source region on the chemical composition

    Science.gov (United States)

    Clemen, Hans-Christian; Schneider, Johannes; Köllner, Franziska; Klimach, Thomas; Pikridas, Michael; Stavroulas, Iasonas; Sciare, Jean; Borrmann, Stephan

    2017-04-01

    The Mediterranean region is one of the most climatically sensitive areas and is influenced by air masses of different origin. Aerosol particles are one important factor contributing to the Earth's radiative forcing, but knowledge about their composition and sources is still limited. Here, we report on results from the INUIT-BACCHUS-ACTRIS campaign, which was conducted at the Cyprus Atmospheric Observatory (CAO, Agia Marina Xyliatou) in Cyprus in April 2016. Our results show that the chemical composition of the aerosol particles in the eastern Mediterranean is strongly dependent on their source region. The composition of particles in a size range between 150 nm and 3 μm was measured using the Aircraft-based Laser ABlation Aerosol MAss spectrometer (ALABAMA), which is a single particle laser ablation instrument using a bipolar time-of-flight mass spectrometer. The mass spectral information on cations and anions allow for the analysis of different molecular fragments. The information about the source regions results from backward trajectories using HYSPLIT Trajectory Model (Trajectory Ensemble) on hourly basis. To assess the influence of certain source regions on the air masses arriving at CAO, we consider the number of trajectories that crossed the respective source region within defined time steps. For a more detailed picture also the height and the velocity of the air masses during their overpass above the source regions will be considered. During the campaign at CAO in April 2016 three main air mass source regions were observed: 1) Northern Central Europe, likely with an enhanced anthropogenic influence (e.g. sulfate and black carbon from combustion processes, fly ash particles from power plants, characterized by Sr and Ba), 2) Southwest Europe, with a higher influence of the Mediterranean Sea including sea salt particles (characterized by, e.g., NaxCly, NaClxNOy), 3) Northern Africa/Sahara, with air masses that are expected to have a higher load of mineral dust

  18. Status of blood transfusion in World Health Organization-Eastern Mediterranean Region (WHO-EMR): Successes and challenges.

    Science.gov (United States)

    Darbandi, Arezoo; Mashati, Pargol; Yami, Amir; Gharehbaghian, Arshia; Namini, Mehdi Tabrizi; Gharehbaghian, Ahmad

    2017-06-01

    Blood products are used for patient treatment and survival in the cases of major surgery, hematological disorders or cancer therapy. Presently the main blood components are not yet replaceable by artificial products and all activities related to blood transfusion is highly dependent on the healthcare development of each country. The World Health Organization Eastern Mediterranean Region (WHO-EMR) comprises of 21 member states with variable socio-economic status effective on blood transfusion activities. The fundamental motivation behind this research was to accumulate some data of blood practices in this region and to have an appropriate image of the WHO-EMR region. The data were collected through the published papers or data, blood transfusion services websites, and the other health official websites like WHO. Among WHO-EMR countries there are some with a nationally organized blood transfusion establishment such as Egypt, Iran, Iraq, Kuwait, Morocco, Oman, Pakistan, and Syria. In a few, blood transfusion administrations are hospital-based like Saudi Arabia. The others are run by Red Crescent such as Bahrain, Tunisia and UEA or by Red Cross like Lebanon. Only Iran and UAE succeed to have 100% voluntary non-remunerated blood donors; however, most of them are still under the weight of family/replacement blood donation such as Afghanistan, Egypt, Iraq, Lebanon, Morocco, Saudi Arabia and Sudan or even paid donors like Pakistan and Yemen. The haemovigilance and training programs have been implemented in some countries including Bahrain, Iran, Jordan, Kuwait, Oman, Qatar, Saudi Arabia, Tunisia and UAE. Unfortunately, there are rare and inaccessible information about some EMR states like Djibouti, Palestine and Somalia so that little data can be independently discovered. In these countries different measures ought to be additionally designated to ensure blood products adequacy and safety such as the development of well-coordinated national blood transfusion centers with

  19. Genetic structure and diversity of indigenous rice (Oryza sativa) varieties in the Eastern Himalayan region of Northeast India.

    Science.gov (United States)

    Choudhury, Baharul; Khan, Mohamed Latif; Dayanandan, Selvadurai

    2013-12-01

    The Eastern Himalayan region of Northeast (NE) India is home to a large number of indigenous rice varieties, which may serve as a valuable genetic resource for future crop improvement to meet the ever-increasing demand for food production. However, these varieties are rapidly being lost due to changes in land-use and agricultural practices, which favor agronomically improved varieties. A detailed understanding of the genetic structure and diversity of indigenous rice varieties is crucial for efficient utilization of rice genetic resources and for developing suitable conservation strategies. To explore the genetic structure and diversity of rice varieties in NE India, we genotyped 300 individuals of 24 indigenous rice varieties representing sali, boro, jum and glutinous types, 5 agronomically improved varieties, and one wild rice species (O. rufipogon) using seven SSR markers. A total of 85 alleles and a very high level of gene diversity (0.776) were detected among the indigenous rice varieties of the region. Considerable level of genetic variation was found within indigenous varieties whereas improved varieties were monoporphic across all loci. The comparison of genetic diversity among different types of rice revealed that sali type possessed the highest gene diversity (0.747) followed by jum (0.627), glutinous (0.602) and boro (0.596) types of indigenous rice varieties, while the lowest diversity was detected in agronomically improved varieties (0.459). The AMOVA results showed that 66% of the variation was distributed among varieties indicating a very high level of genetic differentiation in rice varieties in the region. Two major genetically defined clusters corresponding to indica and japonica groups were detected in rice varieties of the region. Overall, traditionally cultivated indigenous rice varieties in NE India showed high levels of genetic diversity comparable to levels of genetic diversity reported from wild rice populations in various parts of the

  20. Process and domain specificity in regions engaged for face processing: an fMRI study of perceptual differentiation.

    Science.gov (United States)

    Collins, Heather R; Zhu, Xun; Bhatt, Ramesh S; Clark, Jonathan D; Joseph, Jane E

    2012-12-01

    The degree to which face-specific brain regions are specialized for different kinds of perceptual processing is debated. This study parametrically varied demands on featural, first-order configural, or second-order configural processing of faces and houses in a perceptual matching task to determine the extent to which the process of perceptual differentiation was selective for faces regardless of processing type (domain-specific account), specialized for specific types of perceptual processing regardless of category (process-specific account), engaged in category-optimized processing (i.e., configural face processing or featural house processing), or reflected generalized perceptual differentiation (i.e., differentiation that crosses category and processing type boundaries). ROIs were identified in a separate localizer run or with a similarity regressor in the face-matching runs. The predominant principle accounting for fMRI signal modulation in most regions was generalized perceptual differentiation. Nearly all regions showed perceptual differentiation for both faces and houses for more than one processing type, even if the region was identified as face-preferential in the localizer run. Consistent with process specificity, some regions showed perceptual differentiation for first-order processing of faces and houses (right fusiform face area and occipito-temporal cortex and right lateral occipital complex), but not for featural or second-order processing. Somewhat consistent with domain specificity, the right inferior frontal gyrus showed perceptual differentiation only for faces in the featural matching task. The present findings demonstrate that the majority of regions involved in perceptual differentiation of faces are also involved in differentiation of other visually homogenous categories.

  1. Model study of the impact of biogenic emission on regional ozone and the effectiveness of emission reduction scenarios over eastern China

    International Nuclear Information System (INIS)

    Han, Zhiwei; Matsuda, Kazuhide; Ueda, Hiromasa

    2005-01-01

    The impact of biogenic emission on regional ozone and emission control scenarios has been numerically studied through a series of sensitivity model simulations. A typical episode with elevated ozone over eastern China from 12 to 16 August 2001 was investigated by using a tropospheric chemistry and transport model (TCTM), driven by a non-hydrostatic mesoscale model MM5. The meteorological conditions during this period were characterized by high-pressure systems associated with low wind speeds, high temperatures and clear skies. Afternoon ozone concentrations exceeding 80 parts per billion (ppb) occurred over broad areas of eastern China. There is a generally good agreement between simulation and observation, indicating that the TCTM is able to represent major physical and chemical processes of tropospheric ozone and well reproduce the diurnal and day-to-day variability associated with synoptic conditions. The sensitivity analysis reveals a significant influence of biogenic hydrocarbons on regional ozone. Ozone levels are apparently enhanced by biogenic emission over large areas of eastern China. The largest increase up to 30 ppb in daytime average concentration is found in portions of the middle reaches of the Yangtze River, Yangtze Delta and northeast China. However, the response of ozone to biogenic emission varies spatially, showing more sensitivity in polluted areas than that in clean rural areas. The regimes limited by nitrogen oxides (NO x ) and volatile organic carbon (VOC) in eastern China are further investigated with respect to biogenic emission. Ozone shows a clear tendency to shift from VOC limitation to NO x limitation as it moves from urban and industrial areas to rural areas. Most of the rural areas in southern China tend to be NO x limited, whereas most of the northern parts of China appear to be VOC limited. By considering biogenic emission, ozone tends to become more NO x limited and less VOC limited, both in extent and intensity, over eastern

  2. Domain wall oscillation in magnetic nanowire with a geometrically confined region

    Science.gov (United States)

    Sbiaa, R.; Bahri, M. Al; Piramanayagam, S. N.

    2018-06-01

    In conventional magnetic devices such as magnetic tunnel junctions, a steady oscillation of a soft layer magnetization could find its application in various electronic systems. However, these devices suffer from their low output signal and large spectral linewidth. A more elegant scheme based on domain wall oscillation could be a solution to these issues if DW dynamics could be controlled precisely in space and time. In fact, in DW devices, the magnetic configuration of domain wall and its position are strongly dependent on the device geometry and material properties. Here we show that in a constricted device with judiciously adjusted dimensions, a DW can be trapped within the central part and keep oscillating with a single frequency f. For 200 nm by 40 nm nanowire, f was found to vary from 2 GHz to 3 GHz for a current density between 4.8 × 1012 A/m2 and 5.6 × 1012 A/m2. More interestingly, the device fabrication is simply based on two long nanowires connected by adjusting the offset in both x and y directions. This new type of devices enables the conversion of dc-current to an ac-voltage in a controllable manner opening thus the possibility of a new nano-oscillators with better performance.

  3. Importance of Hypervariable Region 2 for Stability and Affinity of a Shark Single-Domain Antibody Specific for Ebola Virus Nucleoprotein.

    Directory of Open Access Journals (Sweden)

    George P Anderson

    Full Text Available Single-domain antibodies derived from the unique New Antigen Receptor found in sharks have numerous potential applications, ranging from diagnostic reagents to therapeutics. Shark-derived single-domain antibodies possess the same characteristic ability to refold after heat denaturation found in single-domain antibodies derived from camelid heavy-chain-only antibodies. Recently, two shark derived single-domain antibodies specific for the nucleoprotein of Ebola virus were described. Our evaluation confirmed their high affinity for the nucleoprotein, but found their melting temperatures to be low relative to most single-domain antibodies. Our first approach towards improving their stability was grafting antigen-binding regions (complementarity determining regions of one of these single-domain antibodies onto a high melting temperature shark single-domain antibody. This resulted in two variants: one that displayed excellent affinity with a low melting temperature, while the other had poor affinity but a higher melting temperature. These new proteins, however, differed in only 3 amino acids within the complementarity determining region 2 sequence. In shark single-domain antibodies, the complementarity determining region 2 is often referred to as hypervariable region 2, as this segment of the antibody domain is truncated compared to the sequence in camelid single-domain antibodies and conventional heavy chain variable domains. To elucidate which of the three amino acids or combinations thereof were responsible for the affinity and stability we made the 6 double and single point mutants that covered the intermediates between these two clones. We found a single amino acid change that achieved a 10°C higher melting temperature while maintaining sub nM affinity. This research gives insights into the impact of the shark sdAb hypervariable 2 region on both stability and affinity.

  4. Development of a regional groundwater flow model for the area of the Idaho National Engineering Laboratory, Eastern Snake River Plain Aquifer

    International Nuclear Information System (INIS)

    McCarthy, J.M.; Arnett, R.C.; Neupauer, R.M.

    1995-03-01

    This report documents a study conducted to develop a regional groundwater flow model for the Eastern Snake River Plain Aquifer in the area of the Idaho National Engineering Laboratory. The model was developed to support Waste Area Group 10, Operable Unit 10-04 groundwater flow and transport studies. The products of this study are this report and a set of computational tools designed to numerically model the regional groundwater flow in the Eastern Snake River Plain aquifer. The objective of developing the current model was to create a tool for defining the regional groundwater flow at the INEL. The model was developed to (a) support future transport modeling for WAG 10-04 by providing the regional groundwater flow information needed for the WAG 10-04 risk assessment, (b) define the regional groundwater flow setting for modeling groundwater contaminant transport at the scale of the individual WAGs, (c) provide a tool for improving the understanding of the groundwater flow system below the INEL, and (d) consolidate the existing regional groundwater modeling information into one usable model. The current model is appropriate for defining the regional flow setting for flow submodels as well as hypothesis testing to better understand the regional groundwater flow in the area of the INEL. The scale of the submodels must be chosen based on accuracy required for the study

  5. A new high background radiation area in the Geothermal region of Eastern Ghats Mobile Belt (EGMB) of Orissa, India

    International Nuclear Information System (INIS)

    Baranwal, V.C.; Sharma, S.P.; Sengupta, D.; Sandilya, M.K.; Bhaumik, B.K.; Guin, R.; Saha, S.K.

    2006-01-01

    A high natural radiation zone is investigated for the first time in a geothermal region of Eastern Ghats Mobile Belt (EGMB) of Orissa state in India. The surrounding area comprises a geothermal region which has surveyed using a portable pulsed Geiger-Muller counter. On the basis of findings of GM counter, an area was marked as a high radiation zone. Soil and rock samples collected from the high radiation zone were analyzed by γ-ray spectrometry (GRS) using NaI(Tl) detector. The radioactivity is found to be contributed mainly by thorium. Concentration of thorium is reported to be very high compared to their normal abundance in crustal rocks. Further, concentrations of 238 U and 40 K are also high compared to normal abundance in crustal rocks but their magnitude is comparatively less than that of thorium. The average concentrations of 238 U (i.e. U(β-γ)), 232 Th and 40 K are found to be 33, 459ppm and 3%, respectively, in soils and 312, 1723ppm and 5%, respectively, in the granitic rocks. Maximum concentrations of 238 U, 232 Th and 40 K are found to be 95, 1194ppm and 4%, respectively, in soils and 1434, 10,590ppm and 8%, respectively, in the granitic rocks. Radioactive element emits various energies in its decay chain. High energies are utilized to estimate the concentration of actual 238 U, 232 Th and 40 K using a NaI(Tl) detector, however, low energies are used for the same in an HPGe detector. Some of the rock samples (eight in number) were also analyzed using HPGe detector for studying the behavior of low energies emitted in the decay series of uranium and thorium. The absorbed gamma dose rate in air and external annual dose rate of the high radiation zone are calculated to be 2431nGy/h and 3.0mSv/y, respectively. It is approximately 10 times greater than the dose rates obtained outside the high radiation zone. The high concentration of uranium and thorium may be one of the possible heat sources together with the normal geothermal gradient for hot springs

  6. Eastern Regional Research Center

    Data.gov (United States)

    Federal Laboratory Consortium — More than 20,000 sq. ft. of space with utilities and equipment for researchat pilot and near commercial scales.Food and bio-based processing pilot plant (10,000 sq....

  7. A retrospective study on the outcomes of cataract surgery in an Eastern Regional Health Authority hospital of Trinidad and Tobago

    Directory of Open Access Journals (Sweden)

    Ebiakpo-aboere Sonron

    2015-09-01

    Full Text Available Background. Worldwide, cataract is a major cause of blindness. The paper aims to evaluate factors associated with borderline and poor outcomes of cataract surgery at an Eastern Regional Health Authority (ERHA hospital in Trinidad and Tobago.Materials and Methods. A hospital-based, retrospective study was done on 401 patients who had undergone cataract surgery (unilateral and bilateral at an ERHA Hospital between March 2009 and September 2014. Data was collected on variables concerning demographic, medical history, surgical history, ocular findings and visual acuity (VA. The outcome variable of interest was Snellen’s post-operative (presenting VA which was transformed into a dichotomous variable with borderline and poor outcomes as one and good outcomes as the other. Data were analysed using univariate and multivariate logistic regression analyses.Results. Good outcome (presenting VA 6/18 or better was seen in 350 (67% eyes. The fitted model consisted of ocular co-morbidity (OR =2.133; 95% CI [1.346–3.380], hypertension (OR = 0.520; 95% CI [0.381–0.928], surgical procedure (OR = 1.56; 95% CI [1.004–2.425], good preoperative VA (OR = 0.388, 95% CI [0.211–0.714], borderline preoperative VA (OR = 0.485; 95% CI = [0.278–0.843] and year of first visit to clinic (OR = 2.243; 95% CI [1.215–4.141].Conclusion. There is a need for community-based outreach to increase awareness of eye health and diseases. It is recommended that the general population is encouraged to take responsibility for personal management. The facilities at the Hospital should also be enhanced.

  8. Defining seascapes for marine unconsolidated shelf sediments in an eastern boundary upwelling region: The southern Benguela as a case study

    Science.gov (United States)

    Karenyi, Natasha; Sink, Kerry; Nel, Ronel

    2016-02-01

    Marine unconsolidated sediment habitats, the largest benthic ecosystem, are considered physically controlled ecosystems driven by a number of local physical processes. Depth and sediment type are recognised key drivers of these ecosystems. Seascape (i.e., marine landscape) habitat classifications are based solely on consistent geophysical features and provide an opportunity to define unconsolidated sediment habitats based on processes which may vary in distribution through space and time. This paper aimed to classify unconsolidated sediment seascapes and explore their diversity in an eastern boundary upwelling region at the macro-scale, using the South African west coast as a case study. Physical variables such as sediment grain size, depth and upwelling-related variables (i.e., maximum chlorophyll concentration, austral summer bottom oxygen concentration and sediment organic carbon content) were included in the analyses. These variables were directly measured through sampling, or collated from existing databases and the literature. These data were analysed using multivariate Cluster, Principal Components Ordination and SIMPER analyses (in PRIMER 6 + with PERMANOVA add-in package). There were four main findings; (i) eight seascapes were identified for the South African west coast based on depth, slope, sediment grain size and upwelling-related variables, (ii) three depth zones were distinguished (inner, middle and outer shelf), (iii) seascape diversity in the inner and middle shelves was greater than the outer shelf, and (iv) upwelling-related variables were responsible for the habitat diversity in both inner and middle shelves. This research demonstrates that the inclusion of productivity and its related variables, such as hypoxia and sedimentary organic carbon, in seascape classifications will enhance the ability to distinguish seascapes on continental shelves, where productivity is most variable.

  9. Regional geologic characteristics of uranium ores and assessment of metallogenetic potentials in the central part of Eastern Liaoning Province

    International Nuclear Information System (INIS)

    Wang Wenguang; Tao Quan; Zhang Shouben

    1997-10-01

    Regional geologic characteristics, metallogenetic conditions and prospects of uranium ores in the central part of the Eastern Liaoning Province of North China is studied systematically. It demonstrates that the Archaean basement of the study area consists of a special type of granite-greenstone belts in China. It is called the granite-greenstone belts of the Liaoning-model, in which the granitic rocks are mainly migmatitic granite and granite-gneiss of migmatitic genesis. The greenstone belts in this area have undergone strong metamorphism. Large amounts of Precambrian geochronological studies have been made with U-Pb isotopic method on zircon; and a new Precambrian geologic time scale has been established. It is also proved that multistage activation of the Early Precambrian basement and the proto-platform took place in Early Proterozoic. Emphases are laid on uranium and thorium abundances and their variations as well as primary uranium contents of rocks in the granite-greenstone terrain and those of the Lower Proterozoic. At the same time, uraninite as accessory mineral in granitic rocks is found to exist more or less. Early Precambrian strata and many kinds of mineral deposits occurring in the strata are in origin chiefly of syngenetic hot brine sedimentation and of submarine extrusive gas-hydrothermal sedimentation superimposed by metamorphism. Metallogenetic features and models of various types of uranium deposits are studied emphatically and compared with similar large deposits abroad. In addition, overall synthetical appraisals are made for this area; and on this basis, prospecting directions and favourable sections of uranium metallization are suggested. (4 refs., 4 tabs.)

  10. Combined multibeam and LIDAR bathymetry data from eastern Long Island Sound and westernmost Block Island Sound-A regional perspective

    Science.gov (United States)

    Poppe, L.J.; Danforth, W.W.; McMullen, K.Y.; Parker, Castle E.; Doran, E.F.

    2011-01-01

    Detailed bathymetric maps of the sea floor in Long Island Sound are of great interest to the Connecticut and New York research and management communities because of this estuary's ecological, recreational, and commercial importance. The completed, geologically interpreted digital terrain models (DTMs), ranging in area from 12 to 293 square kilometers, provide important benthic environmental information, yet many applications require a geographically broader perspective. For example, individual surveys are of limited use for the planning and construction of cross-sound infrastructure, such as cables and pipelines, or for the testing of regional circulation models. To address this need, we integrated 12 multibeam and 2 LIDAR (Light Detection and Ranging) contiguous bathymetric DTMs, produced by the National Oceanic and Atmospheric Administration during charting operations, into one dataset that covers much of eastern Long Island Sound and extends into westernmost Block Island Sound. The new dataset is adjusted to mean lower low water, is gridded to 4-meter resolution, and is provided in UTM Zone 18 NAD83 and geographic WGS84 projections. This resolution is adequate for sea floor-feature and process interpretation but is small enough to be queried and manipulated with standard Geographic Information System programs and to allow for future growth. Natural features visible in the grid include exposed bedrock outcrops, boulder lag deposits of submerged moraines, sand-wave fields, and scour depressions that reflect the strength of the oscillating and asymmetric tidal currents. Bedform asymmetry allows interpretations of net sediment transport. Anthropogenic artifacts visible in the bathymetric data include a dredged channel, shipwrecks, dredge spoils, mooring anchors, prop-scour depressions, buried cables, and bridge footings. Together the merged data reveal a larger, more continuous perspective of bathymetric topography than previously available, providing a fundamental

  11. Severity of work in opinions of rural women living in the Bieszczady region of south-eastern Poland.

    Science.gov (United States)

    Pawlak, Halina; Petkowicz, Beata; Maniak, Barbara; Kuna-Broniowska, Izabela; Petkowicz, Jacek; Buczaj, Agnieszka; Maksym, Piotr; Nowakowicz-Dębek, Bożena; Gawda, Piotr

    2018-03-14

    The objective of the study was recognition of the opinions of rural women living in the Bieszczady region of south-eastern Poland, concerning their perception of the degree of severity of work. The study was conducted among the inhabitants of the Cisna commune. The basic research instrument was a questionnaire form containing 15 items. The study covered 101 women living in the Cisna commune in the Bieszczady. The self-reported degree of work load on a farm was analyzed among women who were occupationally active, and those who were not occupationally active. The effect of assistance from family members on the severity of work perceived by women was considered. The women in the study focused on agro-tourism, a few of them were engaged in agricultural work and the majority worked in household gardens. The study showed that occupationally active women work considerably longer, on average, and are the most loaded, compared to those not engaged in occupational activity. The mean daily time devoted to duties on a farm did not significantly differ between occupationally active and non-active women, and amounted to 380 and 320 minutes, respectively. The majority of women who were non-active occupationally evaluated their household chores as the highest work load. In turn, the women who undertook occupational activity assessed them as most burdensome, despite great help from their family. The body positions assumed while performing field work were: standing, standing-bent-over, and walking. The mean evaluations of work load while standing and standing-bent-over did not significantly differ, but affected the work load among women who, however, could not assess the severity of their work resulting from the body position assumed.

  12. Global change and viticulture in the Mediterranean region: a case of study in north-eastern Spain

    Directory of Open Access Journals (Sweden)

    Joan-Albert Lopez-Bustins

    2014-02-01

    Full Text Available Viticulture in the Mediterranean region has been improved by agronomic methods based on ecophysiological and genetic knowledge of the species and varieties cultivated. Plant growth, yield and quality are highly dependent on climate. Grape sugar content and wine alcohol content are considered as important quality parameters. The objective of our study is to analyse the effects of the current global change on the percentage of alcohol by volume (ABV in red wines from vineyards located in the Montsant Designation of Origin (DO (Priorat County, north-eastern Spain. We present an annual series of percentage of ABV in red wines over the 1984-2008 period (25 years, which is one of the longest series of this viticultural variable in Spain. We do not detect any significant trend of alcohol levels in red wines from the Montsant DO along the 1984-2004 subperiod, but a sharp increase about 1% (by volume is observed after 2004; we statistically checked that the last four years constitute an outlier period in the series. We consider climate evolution over the 1984-2004 period in the study area in order to find some relation with alcohol levels in red wines. Agronomic practices and land cover changes are also taken into account. Results show that the interannual variability of the alcohol levels in red wines are partially explained by temperature and precipitation conditions few days before the vintage. The high percentages of ABV since 2005 may be associated with new trends in viticulture techniques rather than with climate change.

  13. Remediation of surface water polluted by effluent discharges from mining activities in the Eastern Region of Ghana

    International Nuclear Information System (INIS)

    Kusi, Samuel

    2017-07-01

    Heavy metals are very toxic to the environment and humans at large. Exposures to heavy metals have significant health disorders. In this research, the mandate to find novel adsorbent to reduce lead and mercury concentrations from water samples from Birim River in the Eastern Region of Ghana was studied. The turbidity of the water samples from Kibi, Anyinam and Kade indicated that, the river is very turbid (an average of 355 NTU) and therefore not recommended for domestic use without treatment. The modification of rice husk and orange peels with tartaric acid showed that modified rice husk had better binding efficiency for Pb and Hg. A series of batch experiments using tartaric acid modified rice husk (RH-TAM), tartaric acid orange peel modified (OP-TAM), unmodified rice husk (UM-RH) and unmodified orange peel (UM-OP) for the removal of Pb and Hg showed that the sorption processes depended on pH, contact time and adsorbent dosage. A pH of 5 with 0.5 g/20 ml of adsorbent solution maintained at a temperature of 35 o C ± 2 for a period of four (4) hours yielded the highest adsorption efficiency for both modified and unmodified adsorbents. The adsorption efficiencies recorded for RH –TAM and UM-RH were 75. 56 % and 69.93 % respectively for Pb. Similarly, Hg adsorption efficiencies for both RH-TAM and UM-RH were 53. 26 % and 45.11 % respectively. The adsorption efficiencies of OP –TAM was 62.03 % for Pb and 44.57% for Hg. The unmodified orange peel (UM-OP) had the least adsorption efficiencies of 51.88 % for Pb and 42.39% for Hg. The Langmuir isotherm fitted the experimental data for Pb and Hg better than the Freundlich isotherm. (author)

  14. Factors associated with excessively lengthy treatment of tuberculosis in the eastern Paris region of France in 2004

    Directory of Open Access Journals (Sweden)

    Valin Nadia

    2010-08-01

    Full Text Available Abstract Background Few data are available on prescriber adherence to tuberculosis (TB treatment guidelines. In particular, excessively long treatment carries a risk of avoidable adverse effects and represents a waste of healthcare resources. We examined factors potentially associated with excessively long treatment. Methods We reviewed the medical records of patients diagnosed with TB in 2004 in the eastern Paris region. Sociodemographic and clinical factors associated with excessively long treatment were identified by logistic regression analyses. Based on contemporary guidelines, excessively long treatment was defined as more than 6 months of a four-drug regimen for thoracic TB with full sensitive strains, and more than 12 months for patients with extrathoracic TB. Results Analyses concerned 478 patients with a median age of 36.0 ± 13.5 years, of whom 48% were living in precarious conditions (i.e. poor living conditions and/or no health insurance, 80% were born abroad, and 17% were HIV-seropositive. TB was restricted to the chest in 279 patients (isolated pulmonary, pleuropulmonary, and isolated pleural TB in 245, 13, and 21 patients, respectively, exclusively extrathoracic in 115 patients, and mixed in the remaining 84 patients. Treatment was prescribed by a chest specialist in 211 cases (44.1% and 295 patients (61.7% were managed in a single institution. The treatment duration complied with contemporary guidelines in 316 cases (66.1% and was excessively long in 162 cases (33.9%. The median duration of excessively long treatment was 313 days (IQR: 272-412. In multivariate analysis, isolated thoracic TB, previous TB, HIV infection, a prescriber other than a chest specialist, and management in more than one healthcare center during treatment were independently associated with excessively lengthy treatment. Conclusion One-third of TB patients received excessively long treatment, reflecting inadequate awareness of management guidelines or

  15. [Aboveground biomass and nutrient distribution patterns of larch plantation in a montane region of eastern Liaoning Province, China].

    Science.gov (United States)

    Yan, Tao; Zhu, Jiao-Jun; Yang, Kai; Yu, Li-Zhong

    2014-10-01

    Larch is the main timber species of forest plantations in North China. Imbalance in nutrient cycling in soil emerged due to single species composition and mono system structure of plantation. Thus it is necessary to grasp its biomass and nutrients allocation for scientific management and nutrient cycling studies of larch plantation. We measured aboveground biomass (stem, branch, bark and leaf) and nutrient concentrations (C, N, P, K, Ca, Mg, Fe, Mn, Cu and Zn), and analyzed the patterns of accumulation and distribution of 19-year-old larch plantation with diameter at breast height of 12. 8 cm, tree height of 15. 3 m, and density of 2308 trees · hm(-2), in a montane region of eastern Liaoning Province, China. The results showed that aboveground biomass values were 70.26 kg and 162.16 t · hm(-2) for the individual tree of larch and the stand, respectively. There was a significant difference between biomass of the organs, and decreased in the order of stem > branch > bark > leaf. Nutrient accumulation was 749.94 g and 1730.86 kg · hm(-2) for the individual tree of larch and the stand, respectively. Nutrient accumulation of stem was significantly higher than that of branch, bark and leaf, whether it was macro-nutrient or micro-nutrient. Averagely, 749.94 g nutrient elements would be removed from the system when a 19-year-old larch tree was harvested. If only the stem part was removed from the system, the removal of nutrient elements could be reduced by 40.7%.

  16. Burden of Diarrhea in the Eastern Mediterranean Region, 1990–2013: Findings from the Global Burden of Disease Study 2013

    Science.gov (United States)

    Khalil, Ibrahim; Colombara, Danny V.; Forouzanfar, Mohammad Hossein; Troeger, Christopher; Daoud, Farah; Moradi-Lakeh, Maziar; El Bcheraoui, Charbel; Rao, Puja C.; Afshin, Ashkan; Charara, Raghid; Abate, Kalkidan Hassen; El Razek, Mohammed Magdy Abd; Abd-Allah, Foad; Abu-Elyazeed, Remon; Kiadaliri, Aliasghar Ahmad; Akanda, Ali Shafqat; Akseer, Nadia; Alam, Khurshid; Alasfoor, Deena; Ali, Raghib; AlMazroa, Mohammad A.; Alomari, Mahmoud A.; Al-Raddadi, Rajaa Mohammad Salem; Alsharif, Ubai; Alsowaidi, Shirina; Altirkawi, Khalid A.; Alvis-Guzman, Nelson; Ammar, Walid; Antonio, Carl Abelardo T.; Asayesh, Hamid; Asghar, Rana Jawad; Atique, Suleman; Awasthi, Ashish; Bacha, Umar; Badawi, Alaa; Barac, Aleksandra; Bedi, Neeraj; Bekele, Tolesa; Bensenor, Isabela M.; Betsu, Balem Demtsu; Bhutta, Zulfiqar; Bin Abdulhak, Aref A.; Butt, Zahid A.; Danawi, Hadi; Dubey, Manisha; Endries, Aman Yesuf; Faghmous, Imad D. A.; Farid, Talha; Farvid, Maryam S.; Farzadfar, Farshad; Fereshtehnejad, Seyed-Mohammad; Fischer, Florian; Fitchett, Joseph Robert Anderson; Gibney, Katherine B.; Ginawi, Ibrahim Abdelmageem Mohamed; Gishu, Melkamu Dedefo; Gugnani, Harish Chander; Gupta, Rahul; Hailu, Gessessew Bugssa; Hamadeh, Randah Ribhi; Hamidi, Samer; Harb, Hilda L.; Hedayati, Mohammad T.; Hsairi, Mohamed; Husseini, Abdullatif; Jahanmehr, Nader; Javanbakht, Mehdi; Jibat, Tariku; Jonas, Jost B.; Kasaeian, Amir; Khader, Yousef Saleh; Khan, Abdur Rahman; Khan, Ejaz Ahmad; Khan, Gulfaraz; Khoja, Tawfik Ahmed Muthafer; Kinfu, Yohannes; Kissoon, Niranjan; Koyanagi, Ai; Lal, Aparna; Latif, Asma Abdul Abdul; Lunevicius, Raimundas; El Razek, Hassan Magdy Abd; Majeed, Azeem; Malekzadeh, Reza; Mehari, Alem; Mekonnen, Alemayehu B.; Melaku, Yohannes Adama; Memish, Ziad A.; Mendoza, Walter; Misganaw, Awoke; Mohamed, Layla Abdalla Ibrahim; Nachega, Jean B.; Le Nguyen, Quyen; Nisar, Muhammad Imran; Peprah, Emmanuel Kwame; Platts-Mills, James A.; Pourmalek, Farshad; Qorbani, Mostafa; Rafay, Anwar; Rahimi-Movaghar, Vafa; Ur Rahman, Sajjad; Rai, Rajesh Kumar; Rana, Saleem M.; Ranabhat, Chhabi L.; Rao, Sowmya R.; Refaat, Amany H.; Riddle, Mark; Roshandel, Gholamreza; Ruhago, George Mugambage; Saleh, Muhammad Muhammad; Sanabria, Juan R.; Sawhney, Monika; Sepanlou, Sadaf G.; Setegn, Tesfaye; Sliwa, Karen; Sreeramareddy, Chandrashekhar T.; Sykes, Bryan L.; Tavakkoli, Mohammad; Tedla, Bemnet Amare; Terkawi, Abdullah S.; Ukwaja, Kingsley; Uthman, Olalekan A.; Westerman, Ronny; Wubshet, Mamo; Yenesew, Muluken A.; Yonemoto, Naohiro; Younis, Mustafa Z.; Zaidi, Zoubida; Zaki, Maysaa El Sayed; Al Rabeeah, Abdullah A.; Wang, Haidong; Naghavi, Mohsen; Vos, Theo; Lopez, Alan D.; Murray, Christopher J. L.; Mokdad, Ali H.

    2016-01-01

    Diarrheal diseases (DD) are leading causes of disease burden, death, and disability, especially in children in low-income settings. DD can also impact a child's potential livelihood through stunted physical growth, cognitive impairment, and other sequelae. As part of the Global Burden of Disease Study, we estimated DD burden, and the burden attributable to specific risk factors and particular etiologies, in the Eastern Mediterranean Region (EMR) between 1990 and 2013. For both sexes and all ages, we calculated disability-adjusted life years (DALYs), which are the sum of years of life lost and years lived with disability. We estimate that over 125,000 deaths (3.6% of total deaths) were due to DD in the EMR in 2013, with a greater burden of DD in low- and middle-income countries. Diarrhea deaths per 100,000 children under 5 years of age ranged from one (95% uncertainty interval [UI] = 0–1) in Bahrain and Oman to 471 (95% UI = 245–763) in Somalia. The pattern for diarrhea DALYs among those under 5 years of age closely followed that for diarrheal deaths. DALYs per 100,000 ranged from 739 (95% UI = 520–989) in Syria to 40,869 (95% UI = 21,540–65,823) in Somalia. Our results highlighted a highly inequitable burden of DD in EMR, mainly driven by the lack of access to proper resources such as water and sanitation. Our findings will guide preventive and treatment interventions which are based on evidence and which follow the ultimate goal of reducing the DD burden. PMID:27928080

  17. Global change and viticulture in the Mediterranean region: a case of study in north-eastern Spain

    Energy Technology Data Exchange (ETDEWEB)

    Lopez-Bustins, J. A.; Pla, E.; Nadal, M.; Herralde, F. de; Save, R.

    2014-06-01

    Viticulture in the Mediterranean region has been improved by agronomic methods based on eco physiological and genetic knowledge of the species and varieties cultivated. Plant growth, yield and quality are highly dependent on climate. Grape sugar content and wine alcohol content are considered as important quality parameters. The objective of our study is to analyse the effects of the current global change on the percentage of alcohol by volume (ABV) in red wines from vineyards located in the Montsant Designation of Origin (DO) (Priorat County, north-eastern Spain). We present an annual series of percentage of ABV in red wines over the 1984-2008 period (25 years), which is one of the longest series of this viticultural variable in Spain. We do not detect any significant trend of alcohol levels in red wines from the Montsant DO along the 1984-2004 subperiod, but a sharp increase about 1% (by volume) is observed after 2004; we statistically checked that the last four years constitute an outlier period in the series. We consider climate evolution over the 1984-2004 period in the study area in order to find some relation with alcohol levels in red wines. Agronomic practices and land cover changes are also taken into account. Results show that the interannual variability of the alcohol levels in red wines are partially explained by temperature and precipitation conditions few days before the vintage. The high percentages of ABV since 2005 may be associated with new trends in viticulture techniques rather than with climate change. (Author)

  18. Irregular and incomplete primary schooling in rural Ghana. A case-study of late enrolment and early drop-out in the eastern region

    OpenAIRE

    Oduro, Beth Cathrine Fagerlid

    2014-01-01

    This study takes a closer look at the issue of late enrolment and early drop out in a rural area in Eastern Region in Ghana. Children enrolling in school later than the recommended age of six, is a persistent problem in Ghana in spite of a fee free public school. Using qualitative methodology through household interviews in two villages, interviews with teachers and staff at Ghana Educational Service, a registration scheme and diaries the study seeks to unravel some of the stor...

  19. Human resources for health planning and management in the Eastern Mediterranean region: facts, gaps and forward thinking for research and policy

    OpenAIRE

    El-Jardali, Fadi; Jamal, Diana; Abdallah, Ahmad; Kassak, Kassem

    2007-01-01

    Abstract Background The early decades of the 21st century are considered to be the era of human resources for health (HRH). The World Health Report (WHR) 2006 launched the Health Workforce Decade (2006–2015), with high priority given for countries to develop effective workforce policies and strategies. In many countries in the Eastern Mediterranean Region (EMR), particularly those classified as Low and Low-Middle Income Countries (LMICs), the limited knowledge about the nature, scope, composi...

  20. The E-domain region of mechano-growth factor inhibits cellular apoptosis and preserves cardiac function during myocardial infarction.

    Science.gov (United States)

    Mavrommatis, Evangelos; Shioura, Krystyna M; Los, Tamara; Goldspink, Paul H

    2013-09-01

    Insulin-like growth factor-1 (IGF-1) isoforms are expressed via alternative splicing. Expression of the minor isoform IGF-1Eb [also known as mechano-growth factor (MGF)] is responsive to cell stress. Since IGF-1 isoforms differ in their E-domain regions, we are interested in determining the biological function of the MGF E-domain. To do so, a synthetic peptide analog was used to gain mechanistic insight into the actions of the E-domain. Treatment of H9c2 cells indicated a rapid cellular uptake mechanism that did not involve IGF-1 receptor activation but resulted in a nuclear localization. Peptide treatment inhibited the intrinsic apoptotic pathway in H9c2 cells subjected to cell stress with sorbitol by preventing the collapse of the mitochondrial membrane potential and inhibition of caspase-3 activation. Therefore, we administered the peptide at the time of myocardial infarction (MI) in mice. At 2 weeks post-MI cardiac function, gene expression and cell death were assayed. A significant decline in both systolic and diastolic function was evident in untreated mice based on PV loop analysis. Delivery of the E-peptide ameliorated the decline in function and resulted in significant preservation of cardiac contractility. Associated with these changes were an inhibition of pathologic hypertrophy and significantly fewer apoptotic nuclei in the viable myocardium of E-peptide-treated mice post-MI. We conclude that administration of the MGF E-domain peptide may provide a means of modulating local tissue IGF-1 autocrine/paracrine actions to preserve cardiac function, prevent cell death, and pathologic remodeling in the heart.

  1. General Characteristics of Flora and Vegetation Formations of Eastern Anatolia Region and Its Environs (Türkiye

    Directory of Open Access Journals (Sweden)

    Münir ÖZTÜRK

    2015-07-01

    Full Text Available ABSTRACT: Eastern Anatolia and its environs are included in the Irano-Turanian phytogeographical region of Türkiye. The region abounds in highest mountain ranges (average 1900 m of the country some of which are of quarternary age and volcanic character. Many rivers of historical and international importance like Euphrates, Dicle, Murat, Karasu and Aras. Tigris, Aras and Çoruh flow through the region. It experiencens a typical continental climate. Soils are generally of alluvial, colluvial, chestnut-brown, regosal and basaltic types. The area embodies over 8 million ha of meadows and grasslands which is 41% of Türkiye's total pasturelands as such cattle raising is very high in this area. Forest vegetation is represented mainly by Pinus sylvestris, Quercus libani, Q. longipes, Q. brantii, Q. macranthera, Juniperus excelsa and Betula pendula. Most of these are highly degraded. Plant cover is rich in Irano - Turanian elements but we find Mediterranean and Euro-Siberian elements too to some extent, richest families being Asteraceae, Fabaceae and Poaceae, Lamiaceae, Caryophyllaceae and Apiaceae richest genera being Astragalus, Verbascum, Centaurea, Ranunculus, Alyssum, Vicia, Silene, Dianthus, Veronica and Trifolium. The number of endemics is very high, being around 950. And also the region has gene centers of genera Astragalus, Gypsophila, Cousinia, Acanthophyllum etc. The some typical associations one comes across in this area are; Triseto-Pinetum sylvestris, Trifolio-Pinetum sylvestris, Ballato-Rhamnetum pallasii, Caragano-Minuartietum lineatea, Hippophaetum rhamnoidis, Typho-Juncetum inflecii, Hordeetum violaceumii, Deschampsio-Ranunculetum brachylobus, Hordeeto-Ranunculetum comosae and Polygon-Primuletum auriculatae. Dominantly vegetation of the region is steppe. The are a lot of natural plant taxa using local people. Key Words: Eastern Anatolia, Flora, Vegetation, Biodiversity, Geobotany, Endemism, Türkiye. Doğu Anadolu Bölgesi ve

  2. Current status of Crimean-Congo haemorrhagic fever in the World Health Organization Eastern Mediterranean Region: issues, challenges, and future directions.

    Science.gov (United States)

    Al-Abri, Seif S; Abaidani, Idris Al; Fazlalipour, Mehdi; Mostafavi, Ehsan; Leblebicioglu, Hakan; Pshenichnaya, Natalia; Memish, Ziad A; Hewson, Roger; Petersen, Eskild; Mala, Peter; Nhu Nguyen, Tran Minh; Rahman Malik, Mamunur; Formenty, Pierre; Jeffries, Rosanna

    2017-05-01

    Crimean-Congo haemorrhagic fever (CCHF) is the most widespread, tick-borne viral disease affecting humans. The disease is endemic in many regions, such as Africa, Asia, Eastern and Southern Europe, and Central Asia. Recently, the incidence of CCHF has increased rapidly in the countries of the World Health Organization Eastern Mediterranean Region (WHO EMR), with sporadic human cases and outbreaks of CCHF being reported from a number of countries in the region. Despite the rapidly growing incidence of the disease, there are currently no accurate data on the burden of the disease in the region due to the different surveillance systems used for CCHF in these countries. In an effort to increase our understanding of the epidemiology and risk factors for the transmission of the CCHF virus (CCHFV; a Nairovirus of the family Bunyaviridae) in the WHO EMR, and to identify the current knowledge gaps that are hindering effective control interventions, a sub-regional meeting was organized in Muscat, Oman, from December 7 to 9, 2015. This article summarizes the current knowledge of the disease in the region, identifies the knowledge gaps that present challenges for the prevention and control of CCHFV, and details a strategic framework for research and development activities that would be necessary to curb the ongoing and new threats posed by CCHFV. Copyright © 2017 The Author(s). Published by Elsevier Ltd.. All rights reserved.

  3. Current status of Crimean-Congo haemorrhagic fever in the World Health Organization Eastern Mediterranean Region: issues, challenges, and future directions

    Directory of Open Access Journals (Sweden)

    Seif S. Al-Abri

    2017-05-01

    Full Text Available Crimean-Congo haemorrhagic fever (CCHF is the most widespread, tick-borne viral disease affecting humans. The disease is endemic in many regions, such as Africa, Asia, Eastern and Southern Europe, and Central Asia. Recently, the incidence of CCHF has increased rapidly in the countries of the World Health Organization Eastern Mediterranean Region (WHO EMR, with sporadic human cases and outbreaks of CCHF being reported from a number of countries in the region. Despite the rapidly growing incidence of the disease, there are currently no accurate data on the burden of the disease in the region due to the different surveillance systems used for CCHF in these countries. In an effort to increase our understanding of the epidemiology and risk factors for the transmission of the CCHF virus (CCHFV; a Nairovirus of the family Bunyaviridae in the WHO EMR, and to identify the current knowledge gaps that are hindering effective control interventions, a sub-regional meeting was organized in Muscat, Oman, from December 7 to 9, 2015. This article summarizes the current knowledge of the disease in the region, identifies the knowledge gaps that present challenges for the prevention and control of CCHFV, and details a strategic framework for research and development activities that would be necessary to curb the ongoing and new threats posed by CCHFV.

  4. Amino Terminal Region of Dengue Virus NS4A Cytosolic Domain Binds to Highly Curved Liposomes

    Directory of Open Access Journals (Sweden)

    Yu-Fu Hung

    2015-07-01

    Full Text Available Dengue virus (DENV is an important human pathogen causing millions of disease cases and thousands of deaths worldwide. Non-structural protein 4A (NS4A is a vital component of the viral replication complex (RC and plays a major role in the formation of host cell membrane-derived structures that provide a scaffold for replication. The N-terminal cytoplasmic region of NS4A(1–48 is known to preferentially interact with highly curved membranes. Here, we provide experimental evidence for the stable binding of NS4A(1–48 to small liposomes using a liposome floatation assay and identify the lipid binding sequence by NMR spectroscopy. Mutations L6E;M10E were previously shown to inhibit DENV replication and to interfere with the binding of NS4A(1–48 to small liposomes. Our results provide new details on the interaction of the N-terminal region of NS4A with membranes and will prompt studies of the functional relevance of the curvature sensitive membrane anchor at the N-terminus of NS4A.

  5. Euchromatin islands in large heterochromatin domains are enriched for CTCF binding and differentially DNA-methylated regions

    Directory of Open Access Journals (Sweden)

    Wen Bo

    2012-10-01

    Full Text Available Abstract Background The organization of higher order chromatin is an emerging epigenetic mechanism for understanding development and disease. We and others have previously observed dynamic changes during differentiation and oncogenesis in large heterochromatin domains such as Large Organized Chromatin K (lysine modifications (LOCKs, of histone H3 lysine-9 dimethylation (H3K9me2 or other repressive histone posttranslational modifications. The microstructure of these regions has not previously been explored. Results We analyzed the genome-wide distribution of H3K9me2 in two human pluripotent stem cell lines and three differentiated cells lines. We identified > 2,500 small regions with very low H3K9me2 signals in the body of LOCKs, which were termed as euchromatin islands (EIs. EIs are 6.5-fold enriched for DNase I Hypersensitive Sites and 8-fold enriched for the binding of CTCF, the major organizer of higher-order chromatin. Furthermore, EIs are 2–6 fold enriched for differentially DNA-methylated regions associated with tissue types (T-DMRs, reprogramming (R-DMRs and cancer (C-DMRs. Gene ontology (GO analysis suggests that EI-associated genes are functionally related to organ system development, cell adhesion and cell differentiation. Conclusions We identify the existence of EIs as a finer layer of epigenomic architecture within large heterochromatin domains. Their enrichment for CTCF sites and DNAse hypersensitive sites, as well as association with DMRs, suggest that EIs play an important role in normal epigenomic architecture and its disruption in disease.

  6. Inter-annual variability of air mass and acidified pollutants transboundary exchange in the north-eastern part of the EANET region

    Science.gov (United States)

    Gromov, Sergey A.; Trifonova-Yakovleva, Alisa; Gromov, Sergey S.

    2016-04-01

    Anthropogenic emissions, be it exhaust gases or aerosols, stem from multitude of sources and may survive long-range transport within the air masses they were emitted into. So they follow regional and global transport pathways varying under different climatological regimes. Transboundary transfer of pollutants occurs this way and has a significant impact on the ecological situation of the territories neighbouring those of emission sources, as found in a few earlier studies examining the environmental monitoring data [1]. In this study, we employ a relatively facile though robust technique for estimating the transboundary air and concomitant pollutant fluxes using actual or climatological meteorological and air pollution monitoring data. Practically, we assume pollutant transfer being proportional to the horizontal transport of air enclosed in the lower troposphere and to the concentration of the pollutant of interest. The horizontal transport, in turn, is estimated using the mean layer wind direction and strength, or their descriptive statistics at the individual transects of the boundary of interest. The domain of our interest is the segment of Russian continental border in East Asia spanning from 88° E (southern Middle Siberia) to 135° E (Far East at Pacific shore). The data on atmospheric pollutants concentration are available from the Russian monitoring sites of the region-wide Acid Deposition Monitoring Network in East Asia (EANET, http://www.eanet.asia/) Mondy (Baikal area) and Primorskaya (near Vladivostok). The data comprises multi-year continuous measurement of gas-phase and particulate species abundances in air with at least biweekly sampling rate starting from 2000. In the first phase of our study, we used climatological dataset on winds derived from the aerological soundings at Russian stations along the continental border for the 10-year period (1961-1970) by the Research Institute of Hydrometeorological Information - World Data Centre (RIHMI-WDC) [3

  7. Water use and the thermoregulatory behaviour of kangaroos in arid regions: insights into the colonisation of arid rangelands in Australia by the Eastern Grey Kangaroo (Macropus giganteus).

    Science.gov (United States)

    Dawson, Terence J; McTavish, Kirsten J; Munn, Adam J; Holloway, Joanne

    2006-01-01

    The Eastern Grey Kangaroo (Macropus giganteus) occurs mostly in the wetter regions of eastern Australia. However, in the past 30-40 years it has moved into more arid regions (rainfall Kangaroo (Macropus rufus). An increased access to water (supplied for domestic stock) may explain this range extension, but changes in the availability of preferred feed could also be involved. The water use, drinking patterns and thermoregulatory behaviour of these two species of kangaroo have been examined in a semi-free range study, during summer at an arid rangeland site. Foraging was largely nocturnal in both species and during the day they behaved to reduce heat loads. This was especially so for M. giganteus, which showed greater shade seeking. However, it still used more water (72 +/- 2.6 mL kg(-1) day(-1), mean +/- SE) than M. rufus (56 +/- 7.6 mL kg(-1) day(-1)) and drank twice as frequently. Although M. giganteus produced a less concentrated urine (1422 +/- 36 mosmol kg(-1)) than M. rufus (1843 +/- 28 mosmol kg(-1)), kidney physiology did not explain all of the differences in water metabolism between the species. Water from the feed and faecal water retention also appear to be involved. Broadly, a better access to reliable water and the utilisation of mesic microhabitats has enabled M. giganteus to make inroads into the changing rangelands of eastern Australia. However, changes in the vegetation, due to stock grazing, have also favoured M. giganteus, which is a grass eating specialist.

  8. Gas in Eastern Europe

    International Nuclear Information System (INIS)

    Anon.

    1994-01-01

    West European gas companies have long recognised the potential for lucrative business within eastern Europe. But they recognise that the region's integration into the west European system will be far from straightforward, with deals between east European gas companies and their western counterparts invariably containing financial mechanisms, such as barter trade, that are designed to cope with the easterners' shortage of hard currency. (author)

  9. Predominance of genotype 1.1 and emergence of genotype 2.2 classical swine fever viruses in north-eastern region of India.

    Science.gov (United States)

    Roychoudhury, P; Sarma, D K; Rajkhowa, S; Munir, M; Kuchipudi, S V

    2014-08-01

    Classical swine fever (CSF) is a highly contagious and the most important disease of pigs worldwide.CSF is enzootic in pig herds in India and continues to cause huge economic losses to pig farmers. Nearly 40% of the total pig population of India is present in the north-eastern (NE) states where pig husbandry plays an important role in the socio-economic development. Pigs reared in the backyards are the only source of livelihood for a majority of poor tribal population in the region. Hardly any CSF vaccination is currently being undertaken in the unorganized pig farming in the NE region due to economic reasons and vaccine unavailability. A thorough understanding of the current epidemiological status of CSF is essential for the effective control of the disease in the NE region. Hence, we carried out molecular characterization of CSFV isolates from field outbreaks during 2011-2012 in the entire north-eastern region of India to establish the genetic groups of prevalent CSF viruses in the region. A total of 17 CSFV isolates obtained from different parts of the NE region were characterized by comparing the sequences of three partial genomic regions of the virus, that is 150 nt of 5' UTR, 190 nt of E2 and 409 nt of NS5B. Of the 17 CSFV isolates, 15 isolates belonged to 1.1 (88.2%) and two isolates (11.8%) belonged to 2.2 subgenogroup. The genogroup 2.2 CSFV were associated with outbreaks in Arunachal Pradesh that shares international borders with Bhutan, Myanmar and China. Genogroup 2.2 CSFV isolated in the present study shared high level of sequence similarity with 2.2 viruses form China, raising the possibility of virus incursion from this region. In summary, we found a continued predominance of 1.1 subgroup and an emergence of 2.2 subgroup CSFV in NE region of India. © 2014 Blackwell Verlag GmbH.

  10. [Jörg Hackmann (Hrsg.). Vereinskultur und Zivilgesellschaft in Nordosteuropa : regionale Spezifik und europäische Zusammenhänge = Associational culture and civil society in North Eastern Europe : regional features and the European context] / Rüdi

    Index Scriptorium Estoniae

    Ritter, Rüdiger

    2014-01-01

    Arvustus: Vereinskultur und Zivilgesellschaft in Nordosteuropa : regionale Spezifik und europäische Zusammenhänge = Associational culture and civil society in North Eastern Europe : regional features and the European context. Wien: Böhlau Verlag 2012

  11. Challenges for regional innovation policies in Central and Eastern Europe: spatial concentration and foreign control of US patenting

    NARCIS (Netherlands)

    Lengyel, B.; Sebestyén, T.; Leydesdorff, L.

    2015-01-01

    On the basis of patent information available online at the U.S. Patent and Trademark Office (USPTO) we point at two major and interconnected challenges that policy-makers face in Central and Eastern Europe (CEE) when combating the lagging innovation performance. First, we address the spatial

  12. The Effector Domain Region of the Vibrio vulnificus MARTX Toxin Confers Biphasic Epithelial Barrier Disruption and Is Essential for Systemic Spread from the Intestine.

    Directory of Open Access Journals (Sweden)

    Hannah E Gavin

    2017-01-01

    Full Text Available Vibrio vulnificus causes highly lethal bacterial infections in which the Multifunctional Autoprocessing Repeats-in-Toxins (MARTX toxin product of the rtxA1 gene is a key virulence factor. MARTX toxins are secreted proteins up to 5208 amino acids in size. Conserved MARTX N- and C-terminal repeat regions work in concert to form pores in eukaryotic cell membranes, through which the toxin's central region of modular effector domains is translocated. Upon inositol hexakisphosphate-induced activation of the of the MARTX cysteine protease domain (CPD in the eukaryotic cytosol, effector domains are released from the holotoxin by autoproteolytic activity. We previously reported that the native MARTX toxin effector domain repertoire is dispensable for epithelial cellular necrosis in vitro, but essential for cell rounding and apoptosis prior to necrotic cell death. Here we use an intragastric mouse model to demonstrate that the effector domain region is required for bacterial virulence during intragastric infection. The MARTX effector domain region is essential for bacterial dissemination from the intestine, but dissemination occurs in the absence of overt intestinal tissue pathology. We employ an in vitro model of V. vulnificus interaction with polarized colonic epithelial cells to show that the MARTX effector domain region induces rapid intestinal barrier dysfunction and increased paracellular permeability prior to onset of cell lysis. Together, these results negate the inherent assumption that observations of necrosis in vitro directly predict bacterial virulence, and indicate a paradigm shift in our conceptual understanding of MARTX toxin function during intestinal infection. Results implicate the MARTX effector domain region in mediating early bacterial dissemination from the intestine to distal organs-a key step in V. vulnificus foodborne pathogenesis-even before onset of overt intestinal pathology.

  13. C, Sr and Pb isotopic chemostratigraphy in precambrian carbonate sequences in the eastern transversal domain of the Borborema Province, northastern Brazil

    International Nuclear Information System (INIS)

    Santos, V. H.; Ferreira, V.P.; Sial, A.N; Babinski, M; Pimentel, M.M

    2001-01-01

    The Transversal Domain, in the Borborema Structural Province, northeastern Brazil, is characterized by a system of NE-trending, left-lateral, transcurrent mega-structure and dextral E-W trending fault zones (Jardim de Sa, 1994). This domain is formed by supracrustal metasedimentary and metavolcansedimentary sequences overlying a gneissic-migmatitic basement. Geological sequences of this domain exhibit distinct lithotectono-stratigraphy that characterize different terranes, separated by shear zones developed during the Cariris Velhos cycle (1.1-0.95 Ga), and that have been reworked during the Brasiliano orogen at the end of the Neoproterozoic (Brito Neves et al., 1995). The objective of this work is to show the results of C, Sr and Pb isotope studies performed in marble lens located near (and in both sides) the proposed boundary between two tectono-stratigraphic terranes (Alto Moxoto and Rio Capibaribe) in the Transversal Domain (au)

  14. Terahertz time-domain spectroscopy response of amines and amino acids intercalated smectites in far-infrared region

    Energy Technology Data Exchange (ETDEWEB)

    Janek, M., E-mail: marian.janek@fns.uniba.sk [Comenius University, Faculty of Natural Sciences, Department of Physical and Theoretical Chemistry, Mlynská dolina CH1, SK-84215 Bratislava (Slovakia); Zich, D. [Comenius University, Faculty of Natural Sciences, Department of Physical and Theoretical Chemistry, Mlynská dolina CH1, SK-84215 Bratislava (Slovakia); Naftaly, M., E-mail: mira.naftaly@npl.co.uk [National Physical Laboratory, Hampton Rd, Teddington, Middlesex TW11 0LW (United Kingdom)

    2014-06-01

    Layered clay minerals from the smectite group with different chemical composition and resulting layer charge (e.g. pyrophyllite, illite, hectorite and montmorillonite) were characterised for their dielectric properties in the far-infrared region using terahertz-time domain spectroscopy (THz-TDS). Samples with distinct cation exchange capacity such as hectorite and montmorillonite were modified using cation exchange reaction with alkylamines or amino acids. The presence of these species in 2D gallery was proved by X-ray diffraction and Fourier transform infrared spectroscopy. The frequency-dependent refractive index of these minerals was determined in the experimentally accessible range of 0.1–3.0 THz (3–100 cm{sup −1}) using THz-TDS. Pristine samples revealed their refractive indices to be 1.82–2.15 at about 1 THz while the modified montmorillonite samples had their refractive indices changed by organic molecules used for their modification to 1.70–2.35 for amines and 1.97–2.36 for amino acids. The presence of organic substances in 2D gallery of clays was detectable despite the relatively high absorption of smectites with magnitude of 100 cm{sup −1}. - Graphical abstract: Display Omitted - Highlights: • “Guest” molecules in “host” layered material were investigated. • Amines and amino-acids were selected as guest molecules. • Natural and synthetic host with smectite phyllosilicate structure were used. • Dielectric properties were investigated by terahertz time domain spectroscopy. • Resonance absorption peaks of guest were detected in far infrared region.

  15. Short forms of the Utrecht-Management of Identity Commitments Scale (U-MICS) with the domains of job, romantic relationship, and region.

    Science.gov (United States)

    Schubach, Elisabeth; Zimmermann, Julia; Noack, Peter; Neyer, Franz J

    2017-01-01

    The U-MICS is a self-report questionnaire designed to assess the identity dimensions from a domain-specific perspective. The present study reports on the development of a short-form version for the domains of job and romantic relationship in young adults from Germany and extends this scale to include the domain of region (n Sample1  = 95, 84% female, mean age 22.45 years; n Sample2  = 1,795, 71% female, mean age 24.53 years). We found the short form to possess adequate psychometric properties and to demonstrate a factor structure congruent to the long-form version. Regarding validity, the small correlations across domains within dimensions support a domain-specific approach to identity. The associations between the different identity domains with personality traits are similar, indicating a consistent pattern of convergent validity for all domains. We conclude that "region" provides a valuable complement to the established domains that can all be reliably assessed with the U-MICS-Short Form. Copyright © 2016 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  16. Fighting rabies in Eastern Europe, the Middle East and Central Asia--experts call for a regional initiative for rabies elimination.

    Science.gov (United States)

    Aikimbayev, A; Briggs, D; Coltan, G; Dodet, B; Farahtaj, F; Imnadze, P; Korejwo, J; Moiseieva, A; Tordo, N; Usluer, G; Vodopija, R; Vranješ, N

    2014-05-01

    MEEREB is an informal network of rabies experts from the Middle East, Eastern Europe and Central Asia, seeking to eliminate rabies from the region. They met for the second time to review the current rabies situation, both globally and in their respective countries, highlighting current rabies control problems and potential solutions. Success stories in Latin America, in Western Europe, in some Asian countries, as well as in Croatia and Serbia prove that elimination of human rabies is achievable in the MEEREB region. It requires political willingness and cooperation of all stakeholders, including Ministries of Health and of Agriculture; adequate management of animal bites through post-exposure prophylaxis; pre-exposure prophylaxis for populations at high risk of rabies exposure, animal vaccination and humane control of stray dog populations. MEEREB members called for a regional initiative for rabies elimination in Eastern Europe and the Middle East. They are confident that the elimination of human rabies of canine origin can be achieved in the region through adopting a One Health approach, and that campaigns for rabies elimination will have significant benefit for public health, including strengthening the structure for control of other zoonoses. © 2013 Blackwell Verlag GmbH.

  17. Long-lasting Cadomian magmatic activity along an active northern Gondwana margin: U-Pb zircon and Sr-Nd isotopic evidence from the Brunovistulian Domain, eastern Bohemian Massif

    Science.gov (United States)

    Soejono, Igor; Janoušek, Vojtěch; Žáčková, Eliška; Sláma, Jiří; Konopásek, Jiří; Machek, Matěj; Hanžl, Pavel

    2017-09-01

    Cadomian magmatic complexes of the Brunovistulian Domain crop out at the eastern termination of the Bohemian Massif. However, the age, nature and geotectonic affinity of some of pre-Variscan (meta-)igneous rock complexes from this domain are still unknown. Geochronological and geochemical study of the granitic rocks across the Brunovistulian Domain reveals new information about the timing and nature of this magmatic activity originally situated along the northern margin of Gondwana. Zircon U-Pb data (601 ± 3 Ma, Brno Massif; 634 ± 6 Ma, paraautochtonous core of the Svratka Dome; 568 ± 3 Ma, Bíteš orthogneiss) from the allochtonous Moravicum indicate the prolonged magmatic activity within the Brunovistulian Domain during the Ediacaran. The major- and trace-element and Sr-Nd isotopic signatures show heterogeneous geochemical characteristics of the granitic rocks and suggest a magmatic-arc geotectonic setting. The two-stage Depleted Mantle Nd model ages ( c. 1.3-2.0 Ga) indicate derivation of the granitic rocks from a relatively primitive crustal source, as well as from an ancient and evolved continental crust of the Brunovistulian Domain. These results constrain the magmatic-arc activity to c. 635-570 Ma and provide a further evidence for a long-lived (at least c. 65 Myr) and likely episodic subduction-related magmatism at the northern margin of Gondwana. The presence of granitic intrusions derived from variously mature crustal sources at different times suggests heterogeneous crustal segments to having been involved in the magmatic-arc system during its multistage evolution.

  18. Molecular characterization of the haptoglobin.hemoglobin receptor CD163. Ligand binding properties of the scavenger receptor cysteine-rich domain region

    DEFF Research Database (Denmark)

    Madsen, Mette; Møller, Holger J; Nielsen, Marianne Jensby

    2004-01-01

    CD163 is the macrophage receptor for endocytosis of haptoglobin.hemoglobin complexes. The extracellular region consisting of nine scavenger receptor cysteine rich (SRCR) domains also circulates in plasma as a soluble protein. By ligand binding analysis of a broad spectrum of soluble CD163...... truncation variants, the amino-terminal third of the SRCR region was shown to be crucial for the binding of haptoglobin.hemoglobin complexes. By Western blotting of the CD163 variants, a panel of ten monoclonal antibodies was mapped to SRCR domains 1, 3, 4, 6, 7, and 9, respectively. Only the two antibodies...... to CD163 demonstrated that optimal ligand binding requires physiological plasma calcium concentrations, and an immediate ligand release occurs at the low calcium concentrations measured in acidifying endosomes. In conclusion, SRCR domain 3 of CD163 is an exposed domain and a critical determinant...

  19. Development of a spatial forest data base for the eastern boreal forest region of Ontario. Forest fragmentation and biodiversity project technical report No. 14

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-12-31

    In 1991, a spatial forest database over large regions of Ontario was initiated as the basis for research into forest fragmentation and biodiversity using data generated from the digital analysis of LANDSAT thematic mapper satellite data integrated into a geographic information system (GIS). The project was later extended into the eastern segment of the Boreal forest system. This report describes preparation of the spatial forest data base over the eastern Boreal Forest Region that extends from the northern boundary of the Great Lakes-St. Lawrence Forest Region and the southern margin of the James Bay Lowland, between the Ontario-Quebec border and a point west of Michipicoten on Lake Superior. The report describes the methodology used to produce the data base and results, including mapping of water, dense and sparse conifer forest, mixed forest, dense and sparse deciduous forest, poorly vegetated areas, recent cutovers of less than 10 years, old cutovers and burns, recent burns of less than 10 years, wetlands, bedrock outcrops, agriculture, built-up areas, and mine tailings.

  20. Regional brain amyloid-β accumulation associates with domain-specific cognitive performance in Parkinson disease without dementia.

    Science.gov (United States)

    Akhtar, Rizwan S; Xie, Sharon X; Chen, Yin J; Rick, Jacqueline; Gross, Rachel G; Nasrallah, Ilya M; Van Deerlin, Vivianna M; Trojanowski, John Q; Chen-Plotkin, Alice S; Hurtig, Howard I; Siderowf, Andrew D; Dubroff, Jacob G; Weintraub, Daniel

    2017-01-01

    Parkinson disease patients develop clinically significant cognitive impairment at variable times over their disease course, which is often preceded by milder deficits in memory, visuo-spatial, and executive domains. The significance of amyloid-β accumulation to these problems is unclear. We hypothesized that amyloid-β PET imaging by 18F-florbetapir, a radiotracer that detects fibrillar amyloid-β plaque deposits, would identify subjects with global cognitive impairment or poor performance in individual cognitive domains in non-demented Parkinson disease patients. We assessed 61 non-demented Parkinson disease patients with detailed cognitive assessments and 18F-florbetapir PET brain imaging. Scans were interpreted qualitatively (positive or negative) by two independent nuclear medicine physicians blinded to clinical data, and quantitatively by a novel volume-weighted method. The presence of mild cognitive impairment was determined through an expert consensus process using Level 1 criteria from the Movement Disorder Society. Nineteen participants (31.2%) were diagnosed with mild cognitive impairment and the remainder had normal cognition. Qualitative 18F-florbetapir PET imaging was positive in 15 participants (24.6%). Increasing age and presence of an APOE ε4 allele were associated with higher composite 18F-florbetapir binding. In multivariable models, an abnormal 18F-florbetapir scan by expert rating was not associated with a diagnosis of mild cognitive impairment. However, 18F-florbetapir retention values in the posterior cingulate gyrus inversely correlated with verbal memory performance. Retention values in the frontal cortex, precuneus, and anterior cingulate gyrus retention values inversely correlated with naming performance. Regional cortical amyloid-β amyloid, as measured by 18F-florbetapir PET, may be a biomarker of specific cognitive deficits in non-demented Parkinson disease patients.

  1. Regional brain amyloid-β accumulation associates with domain-specific cognitive performance in Parkinson disease without dementia.

    Directory of Open Access Journals (Sweden)

    Rizwan S Akhtar

    Full Text Available Parkinson disease patients develop clinically significant cognitive impairment at variable times over their disease course, which is often preceded by milder deficits in memory, visuo-spatial, and executive domains. The significance of amyloid-β accumulation to these problems is unclear. We hypothesized that amyloid-β PET imaging by 18F-florbetapir, a radiotracer that detects fibrillar amyloid-β plaque deposits, would identify subjects with global cognitive impairment or poor performance in individual cognitive domains in non-demented Parkinson disease patients. We assessed 61 non-demented Parkinson disease patients with detailed cognitive assessments and 18F-florbetapir PET brain imaging. Scans were interpreted qualitatively (positive or negative by two independent nuclear medicine physicians blinded to clinical data, and quantitatively by a novel volume-weighted method. The presence of mild cognitive impairment was determined through an expert consensus process using Level 1 criteria from the Movement Disorder Society. Nineteen participants (31.2% were diagnosed with mild cognitive impairment and the remainder had normal cognition. Qualitative 18F-florbetapir PET imaging was positive in 15 participants (24.6%. Increasing age and presence of an APOE ε4 allele were associated with higher composite 18F-florbetapir binding. In multivariable models, an abnormal 18F-florbetapir scan by expert rating was not associated with a diagnosis of mild cognitive impairment. However, 18F-florbetapir retention values in the posterior cingulate gyrus inversely correlated with verbal memory performance. Retention values in the frontal cortex, precuneus, and anterior cingulate gyrus retention values inversely correlated with naming performance. Regional cortical amyloid-β amyloid, as measured by 18F-florbetapir PET, may be a biomarker of specific cognitive deficits in non-demented Parkinson disease patients.

  2. Hypodense regions (holes) in the retinal nerve fiber layer in frequency-domain OCT scans of glaucoma patients and suspects.

    Science.gov (United States)

    Xin, Daiyan; Talamini, Christine L; Raza, Ali S; de Moraes, Carlos Gustavo V; Greenstein, Vivienne C; Liebmann, Jeffrey M; Ritch, Robert; Hood, Donald C

    2011-09-09

    To better understand hypodense regions (holes) that appear in the retinal nerve fiber layer (RNFL) of frequency-domain optical coherence tomography (fdOCT) scans of patients with glaucoma and glaucoma suspects. Peripapillary circle (1.7-mm radius) and cube optic disc fdOCT scans were obtained on 208 eyes from 110 patients (57.4 ± 13.2 years) with glaucomatous optic neuropathy (GON) and 45 eyes of 45 controls (48.0 ± 12.6 years) with normal results of fundus examination. Holes in the RNFL were identified independently by two observers on the circle scans. Holes were found in 33 (16%) eyes of 28 (25%) patients; they were not found in any of the control eyes. Twenty-four eyes had more than one hole. Although some holes were relatively large, others were small. In general, the holes were located adjacent to blood vessels; only three eyes had isolated holes that were not adjacent to a vessel. The holes tended to be in the regions that are thickest in healthy controls and were associated with arcuate defects in patients. Holes were not seen in the center of the temporal disc region. They were more common in the superior (25 eyes) than in the inferior (15 eyes) disc. Of the 30 eyes with holes with reliable visual fields, seven were glaucoma suspect eyes with normal visual fields. The holes in the RNFL seen in patients with GON were probably due to a local loss of RNFL fibers and can occur in the eyes of glaucoma suspects with normal visual fields.

  3. Insights into amyloid-like aggregation of H2 region of the C-terminal domain of nucleophosmin.

    Science.gov (United States)

    Russo, Anna; Diaferia, Carlo; La Manna, Sara; Giannini, Cinzia; Sibillano, Teresa; Accardo, Antonella; Morelli, Giancarlo; Novellino, Ettore; Marasco, Daniela

    2017-02-01

    Nucleophosmin (NPM1) is a multifunctional protein involved in a variety of biological processes including the pathogenesis of several human malignancies and is the most frequently mutated gene in Acute Myeloid Leukemia (AML). To deepen the role of protein regions in its biological activities, lately we reported on the structural behavior of dissected C-terminal domain (CTD) helical fragments. Unexpectedly the H2 (residues 264-277) and H3 AML-mutated regions showed a remarkable tendency to form amyloid-like assemblies with fibrillar morphology and β-sheet structure that resulted as toxic when exposed to human neuroblastoma cells. More recently NPM1 was found to be highly expressed and toxic in neurons of mouse models of Huntington's disease (HD). Here we investigate the role of each residue in the β-strand aggregation process of H2 region of NPM1 by performing a systematic alanine scan of its sequence and structural and kinetic analyses of aggregation of derived peptides by means of Circular Dichorism (CD) and Thioflavin T (Th-T) assay. These solution state investigations pointed out the crucial role exerted by the basic amyloidogenic stretch of H2 (264-271) and to shed light on the initial and main interactions involved in fibril formation we performed studies on fibrils deriving from the related Ala peptides through the analysis of fibrils with birefringence of polarized optical microscopy and wide-angle X-ray scattering (WAXS). This analysis suggested that the presence of branched Ile 269 conferred preferential packing patterns that, instead, appeared geometrically hampered by the aromatic side-chain of Phe 268 . Present investigations could be useful to deepen the knowledge of AML molecular mechanisms and the role of cytoplasmatic aggregates of NPM1c+. Copyright © 2016 Elsevier B.V. All rights reserved.

  4. Health disparities among the western, central and eastern rural regions of China after a decade of health promotion and disease prevention programming.

    Science.gov (United States)

    Zhang, Xi-Fan; Tian, Xiang-Yang; Cheng, Yu-Lan; Feng, Zhan-Chun; Wang, Liang; Southerland, Jodi

    2015-08-01

    Health disparities between the western, central and eastern regions of rural China, and the impact of national health improvement policies and programming were assessed. A total of 400 counties were randomly sampled. ANOVA and Logistic regression modeling were employed to estimate differences in health outcomes and determinants. Significant differences were found between the western, central and eastern rural regions in community infrastructure and health outcomes. From 2000 to 2010, health indicators in rural China were improved significantly, and the infant mortality rate (IMR), maternal mortality rate (MMR) and under 5 mortality rate (U5MR) had fallen by 62.79%, 71.74% and 61.92%, respectively. Central rural China had the greatest decrease in IMR (65.05%); whereas, western rural China had the greatest reduction in MMR (72.99%) but smallest reduction in U5MR (57.36%). Despite these improvements, Logistic regression analysis showed regional differences in key health outcome indicators (odds ratios): IMR (central: 2.13; western: 5.31), U5MR (central: 2.25; western: 5.69), MMR (central: 1.94; western: 3.31), and prevalence of infectious diseases (central: 1.62; western: 3.58). The community infrastructure and health outcomes of the western and central rural regions of China have been improved markedly during the first decade of the 21st century. However, health disparities still exist across the three regions. National efforts to increase per capita income, community empowerment and mobilization, community infrastructure, capacity of rural health facilities, and health literacy would be effective policy options to attain health equity.

  5. Concentrations of some macro and micro plant nutrient of cultivated soils in Central and Eastern Blacksea Region and their mapping by inverse distance weighted (IDW method

    Directory of Open Access Journals (Sweden)

    Mehmet Arif Özyazıcı

    2015-11-01

    Full Text Available The aim of this study was to determine plant nutrients content and to in terms of soil variables their soil database and generate maps of their distribution on agricultural land in Central and Eastern Black Sea Region using geographical information system (GIS. In this research, total 3400 soil samples (0-20 cm depth were taken at 2.5 x 2.5 km grid points representing agricultural soils. Total nitrogen, extractable calcium, magnesium, sodium, boron, iron, copper, zinc and manganese contents were analysed in collected soil samples. Analysis results of these samples were classified and evaluated for deficiency, sufficiency or excess with respect to plant nutrients. Afterwards, in terms of GIS, a soil database and maps for current status of the study area were created by using inverse distance weighted (IDW interpolation method. According to this research results, it was determined sufficient plant nutrient elements in terms of total nitrogen, extractable iron, copper and manganese in arable soils of Central and Eastern Blacksea Region while, extractable calcium, magnesium, sodium were found good and moderate level in 66.88%, 81.44% and 64.56% of total soil samples, respectively. In addition, insufficient boron and zinc concentration were found in 34.35% and 51.36% of soil samples, respectively.

  6. Policy-Relevant Context of Waterpipe Tobacco Smoking among University Students in Six Countries Across the Eastern Mediterranean Region: A Qualitative Study

    Science.gov (United States)

    Salloum, Ramzi G; Abu-Rmeileh, Niveen; Hamadeh, Randah; Thomas, Justin; Mostafa, Aya; Yusufali, Afzalhussein; Kheirallah, Khalid A; Macauda, Mark M; Theis, Ryan P; Kadi, Lama El; Johnson, Evan J; Darawad, Muhammad W; Nakkash, Rima

    2017-01-01

    Background: Waterpipe tobacco smoking rates in the Eastern Mediterranean region are some of the highest worldwide, especially among young people. This study aimed to improve our knowledge of the policy-relevant context of waterpipe smoking among six countries in the Eastern Mediterranean region. Methods: In-depth interviews were conducted in Bahrain, Egypt, Jordan, Lebanon, Palestine, and the United Arab Emirates. Participants were young adult university students (18-29 years) from both genders who had ever smoked the waterpipe, recruited from universities participating in this study. Directed content analysis was used to analyze the transcripts. Results: A total of 53 in-depth interviews were conducted in Arabic in 2016. Findings were organized around 5 themes: waterpipe product characteristics; patterns of waterpipe smoking; the waterpipe café setting; perceived health consequences; and health warning labels. Waterpipe smoking was commonly perceived as a safe alternative to cigarettes. Waterpipe tobacco was reported to be widely accessible and affordable to young participants. There is a lack of knowledge among waterpipe smokers about the associated health effects. Warning labels are effective at communicating health risks associated with waterpipe smoking. Conclusions: Regulatory frameworks for waterpipe tobacco smoking should be developed and enforced, including waterpipe-specific health warning labels that elucidate the harmful effects of waterpipe smoking. PMID:28952296

  7. Prevalence of penicillin and erythromycin resistance among invasive Streptococcus pneumoniae isolates reported by laboratories in the southern and eastern Mediterranean region.

    Science.gov (United States)

    Borg, M A; Tiemersma, E; Scicluna, E; van de Sande-Bruinsma, N; de Kraker, M; Monen, J; Grundmann, H

    2009-03-01

    Information about the epidemiology of resistance in Streptococcus pneumoniae within southern and eastern countries of the Mediterranean region is incomplete, as reports have been sporadic and difficult to compare. Over a 36-month period, from 2003 to 2005, the ARMed project collected 1298 susceptibility test results of invasive isolates of S. pneumoniae from blood and spinal fluid cultures routinely processed within 59 participating laboratories situated in Algeria, Cyprus, Egypt, Jordan, Lebanon, Malta, Morocco, Tunisia and Turkey. Overall, 26% (335) of isolates were reported as non-susceptible to penicillin, with the highest proportions being reported from Algeria (44%) and Lebanon (40%). During the same time period, the highest proportions of pneumococci that were not susceptible to erythromycin were reported from Malta (46%) and Tunisia (39%). Proportions of dual non-susceptibility in excess of 5% were found in laboratories in Algeria, Tunisia, Lebanon, Jordan and Turkey. ARMed data on the antimicrobial resistance epidemiology of S. pneumoniae in the southern and eastern Mediterranean region provided evidence of high rates of resistance, especially to penicillin. This evidence calls for a greater focus on the identification of relevant drivers of resistance and on the implemention of effective practices in order to address the problem of resistence.

  8. Ribosomal L1 domain and lysine-rich region are essential for CSIG/ RSL1D1 to regulate proliferation and senescence

    International Nuclear Information System (INIS)

    Ma, Liwei; Zhao, Wenting; Zheng, Quanhui; Chen, Tianda; Qi, Ji; Li, Guodong; Tong, Tanjun

    2016-01-01

    The expression change of cellular senescence-associated genes is underlying the genetic foundation of cellular senescence. Using a suppressive subtractive hybridization system, we identified CSIG (cellular senescence-inhibited gene protein; RSL1D1) as a novel senescence-associated gene. CSIG is implicated in various process including cell cycle regulation, apoptosis, and tumor metastasis. We previously showed that CSIG plays an important role in regulating cell proliferation and cellular senescence progression through inhibiting PTEN, however, which domain or region of CSIG contributes to this function? To clarify this question, we investigated the functional importance of ribosomal L1 domain and lysine (Lys) -rich region of CSIG. The data showed that expression of CSIG potently reduced PTEN expression, increased cell proliferation rates, and reduced the senescent phenotype (lower SA-β-gal activity). By contrast, neither the expression of CSIG N- terminal (NT) fragment containing the ribosomal L1 domain nor C-terminal (CT) fragment containing Lys-rich region could significantly altered the levels of PTEN; instead of promoting cell proliferation and delaying cellular senescence, expression of CSIG-NT or CSIG-CT inhibited cell proliferation and accelerated cell senescence (increased SA-β-gal activity) compared to either CSIG over-expressing or control (empty vector transfected) cells. The further immunofluorescence analysis showed that CSIG-CT and CSIG-NT truncated proteins exhibited different subcellular distribution with that of wild-type CSIG. Conclusively, both ribosomal L1 domain and Lys-rich region of CSIG are critical for CSIG to act as a regulator of cell proliferation and cellular senescence. - Highlights: • The ribosomal L1 domain and lysine-rich region of CSIG were expressed. • They are critical for CSIG to regulate proliferation and senescence. • CSIG and its domains exhibit different subcellular distribution.

  9. Ribosomal L1 domain and lysine-rich region are essential for CSIG/ RSL1D1 to regulate proliferation and senescence

    Energy Technology Data Exchange (ETDEWEB)

    Ma, Liwei; Zhao, Wenting; Zheng, Quanhui; Chen, Tianda; Qi, Ji; Li, Guodong; Tong, Tanjun, E-mail: tztong@bjmu.edu.cn

    2016-01-15

    The expression change of cellular senescence-associated genes is underlying the genetic foundation of cellular senescence. Using a suppressive subtractive hybridization system, we identified CSIG (cellular senescence-inhibited gene protein; RSL1D1) as a novel senescence-associated gene. CSIG is implicated in various process including cell cycle regulation, apoptosis, and tumor metastasis. We previously showed that CSIG plays an important role in regulating cell proliferation and cellular senescence progression through inhibiting PTEN, however, which domain or region of CSIG contributes to this function? To clarify this question, we investigated the functional importance of ribosomal L1 domain and lysine (Lys) -rich region of CSIG. The data showed that expression of CSIG potently reduced PTEN expression, increased cell proliferation rates, and reduced the senescent phenotype (lower SA-β-gal activity). By contrast, neither the expression of CSIG N- terminal (NT) fragment containing the ribosomal L1 domain nor C-terminal (CT) fragment containing Lys-rich region could significantly altered the levels of PTEN; instead of promoting cell proliferation and delaying cellular senescence, expression of CSIG-NT or CSIG-CT inhibited cell proliferation and accelerated cell senescence (increased SA-β-gal activity) compared to either CSIG over-expressing or control (empty vector transfected) cells. The further immunofluorescence analysis showed that CSIG-CT and CSIG-NT truncated proteins exhibited different subcellular distribution with that of wild-type CSIG. Conclusively, both ribosomal L1 domain and Lys-rich region of CSIG are critical for CSIG to act as a regulator of cell proliferation and cellular senescence. - Highlights: • The ribosomal L1 domain and lysine-rich region of CSIG were expressed. • They are critical for CSIG to regulate proliferation and senescence. • CSIG and its domains exhibit different subcellular distribution.

  10. Hard-magnetic surface layer effect on the erbium orthoferrite plate domain structure in the region of gradual spin reorientation

    International Nuclear Information System (INIS)

    Belyaeva, A.I.; Vojtsenya, S.V.; Yur'ev, V.P.

    1988-01-01

    Rearrangement of domain structures in the erbium orthoferrite plates with hard-magnetic surface layer is investigated during gradual spin reorientation. This phenomenon is explained by means of the proposed physical models. It is shown that in these plates an approach to the temperature interval of spin reorientation causes a decrease in the density of energy of domain walls separating the internal and surface domains. This decrease results in transition to the domain structure which are close to equilibrium ones inside the crystal. 30 refs.; 4 figs

  11. C-terminal region of MAP7 domain containing protein 3 (MAP7D3 promotes microtubule polymerization by binding at the C-terminal tail of tubulin.

    Directory of Open Access Journals (Sweden)

    Saroj Yadav

    Full Text Available MAP7 domain containing protein 3 (MAP7D3, a newly identified microtubule associated protein, has been shown to promote microtubule assembly and stability. Its microtubule binding region has been reported to consist of two coiled coil motifs located at the N-terminus. It possesses a MAP7 domain near the C-terminus and belongs to the microtubule associated protein 7 (MAP7 family. The MAP7 domain of MAP7 protein has been shown to bind to kinesin-1; however, the role of MAP7 domain in MAP7D3 remains unknown. Based on the bioinformatics analysis of MAP7D3, we hypothesized that the MAP7 domain of MAP7D3 may have microtubule binding activity. Indeed, we found that MAP7 domain of MAP7D3 bound to microtubules as well as enhanced the assembly of microtubules in vitro. Interestingly, a longer fragment MDCT that contained the MAP7 domain (MD with the C-terminal tail (CT of the protein promoted microtubule polymerization to a greater extent than MD and CT individually. MDCT stabilized microtubules against dilution induced disassembly. MDCT bound to reconstituted microtubules with an apparent dissociation constant of 3.0 ± 0.5 µM. An immunostaining experiment showed that MDCT localized along the length of the preassembled microtubules. Competition experiments with tau indicated that MDCT shares its binding site on microtubules with tau. Further, we present evidence indicating that MDCT binds to the C-terminal tail of tubulin. In addition, MDCT could bind to tubulin in HeLa cell extract. Here, we report a microtubule binding region in the C-terminal region of MAP7D3 that may have a role in regulating microtubule assembly dynamics.

  12. Thermal conditions of the grape growing season within the North-Eastern steppe land of Ukraine (on the example of Kharkiv region

    Directory of Open Access Journals (Sweden)

    Борис Шуліка

    2016-10-01

    Full Text Available The article analyzes the results of the thermal conditions observations within the North-Eastern steppe land of Ukraine as one of the most important factors for successful cultivation of grapes, thus providing crop productivity. Considering the effect of thermal factors, it can be noted that the intensity and speed of life processes of plants are well- defined under temperature conditions only in the circumstances where other environmental factors are not limited. The thermal regime was initially taken into account in practice in XVII century. In XIX century the agro-climatic areas to grow grapes were determined in North-Eastern steppe land of Ukraine. Detailed studies of agro-climatic conditions of specific areas can more thoroughly to make conclusions and recommendations for the cultivation of grapes as a whole in the territory, and specifically in those areas were given. In studying the thermal balance of the territory the average and extreme temperature should be paid attention to. Characteristic features of the thermal regime are given in this paper based on the study of atmospheric phenomena, geomorphology and territories with radiation influence and water flow regime. Thermal treatment is subjected to anthropogenic influence, and in cultivating tenants can use appropriate agricultural practices (conceal bushes, warm soil and air, and even crops in protective ground, in greenhouses. Characteristically, technology of greenhouses growers is even used in Kherson region. These data can be used in neighborhood and the adjacent areas, especially they are useful for the practice of growing grapes. The possibility of successful cultivation of dozens of grape varieties in the North-Eastern steppe land of Ukraine has been well-grounded.

  13. Long range transport of acidic and polluted events from eastern Europe to the remote regions of Scotland

    International Nuclear Information System (INIS)

    Landsberger, S.; Davies, T.D.; Jickells, T.D.; Tranter, M.

    1991-01-01

    More than 60 daily snowfall samples were collected throughout a snow season at an altitude of 1,100 meters in Cairngorm Mountains in Scotland. Concentrations of major ions, trace metals, rare-earths, carbon and pH were measured in the aqueous and particulate phase. The techniques of neutron activation analysis, inductively coupled plasma mass spectrometry and ion chromatography were employed. Factor analysis indicated a marine and a combined anthropogenic and crustal source. Classification of back-trajectories showed that the events are heavily sector dependent: Eastern Europe and the Baltic dominating the transport of the polluted events. A very strong correlation was observed between low pH and high carbon concentrations in the particulate matter

  14. Determinant of Adult Education Program: A Critical Analysis of Adult Education in Some Selected Training Centers of Eastern Regions

    Directory of Open Access Journals (Sweden)

    Yilfashewa Seyoum

    2016-10-01

    Full Text Available The purpose of this study was to analyze the factors affecting adult education in the eastern part of Ethiopia. The study employed a survey design that involved qualitative and quantitative approaches. A stratified random sampling technique was used to select 515 male and 285 female respondents. A questionnaire and an interview for collecting information from the primary sources were designed and implemented. Data were analyzed with linear correlation and Ordinary Least Square (OLS regression. The findings indicated that the relationship of overall adult learning achievement to assessment of learning (r = 0,29, P < 0,01, and the methods used by facilitators (r = 0,23, P < 0,01 is positive and significant. The regression model demonstrated that overall adult learning condition is significantly affected by variables such as relevance of the content, methods of teaching, assessment of learning outcome, and locality of the adult education learners. 

  15. Middle East, Russia and Caspian region - new geopolitics for oil and gas flows in the Eastern hemisphere

    International Nuclear Information System (INIS)

    Konoplyanik, A.

    1998-01-01

    The Caspian Oil Basin and its would-be impact on the world energy sales has been a big talking issue of late. The Caspian Rim states will join the international oil/gas market simultaneously with new Oil Industry projects coming on-stream in Russia. Both Russia and Caspian states will influence the existing oil/gas flows and balance of forces on the oil/gas markets of the Eastern Hemisphere. What will be the resultant of these two vectors? Will a stronger stand of Russia as one of the existing world market participants and a new big rival - the Caspian states, exert a profound influence on the competitive rating of the Middle East countries as oil/gas exporting majors? Let us try to answer the questions within this contribution. (orig./RHM)

  16. Deforestation as a result of wildfire incidence in the Worobong Forest Reserve in the Eastern Region of Ghana

    Science.gov (United States)

    Danquah, S.

    2009-04-01

    This submission captures report on the perennial occurrence of wildfires and their accompanying effects on the inhabitants and the fringe forest communities in the Worobong Forest Reserve within the Eastern part of Ghana. Wildfire continues to be the single serious threat to the sustainable development and management of forest and wildlife resources in Ghana, thus depriving indigenous fringe forest communities of enormous socio-economic benefit of the forest. Locally, fire is used in the preparation of farm lands, tapping of palm-wine, charcoal production, honey harvesting, etc. This paper identifies some of the effects of wildfires on the indigenous communities and various interventions made to address the wildfire menace in the area of study over the years. Keywords: Wildfire, Fringe Forest Communities, Sustainable Development Resources, Socio-Economic Benefits

  17. Understanding and simulating the link between African easterly waves and Atlantic tropical cyclones using a regional climate model: the role of domain size and lateral boundary conditions

    Energy Technology Data Exchange (ETDEWEB)

    Caron, Louis-Philippe [MISU, Stockholm University, Stockholm (Sweden); Universite du Quebec a Montreal, CRCMD Network, Montreal, QC (Canada); Jones, Colin G. [Swedish Meterological and Hydrological Institute, Rossby Center, Norrkoeping (Sweden)

    2012-07-15

    Using a suite of lateral boundary conditions, we investigate the impact of domain size and boundary conditions on the Atlantic tropical cyclone and african easterly Wave activity simulated by a regional climate model. Irrespective of boundary conditions, simulations closest to observed climatology are obtained using a domain covering both the entire tropical Atlantic and northern African region. There is a clear degradation when the high-resolution model domain is diminished to cover only part of the African continent or only the tropical Atlantic. This is found to be the result of biases in the boundary data, which for the smaller domains, have a large impact on TC activity. In this series of simulations, the large-scale Atlantic atmospheric environment appears to be the primary control on simulated TC activity. Weaker wave activity is usually accompanied by a shift in cyclogenesis location, from the MDR to the subtropics. All ERA40-driven integrations manage to capture the observed interannual variability and to reproduce most of the upward trend in tropical cyclone activity observed during that period. When driven by low-resolution global climate model (GCM) integrations, the regional climate model captures interannual variability (albeit with lower correlation coefficients) only if tropical cyclones form in sufficient numbers in the main development region. However, all GCM-driven integrations fail to capture the upward trend in Atlantic tropical cyclone activity. In most integrations, variations in Atlantic tropical cyclone activity appear uncorrelated with variations in African easterly wave activity. (orig.)

  18. Prevalence of immunoglobulin E-mediated food allergy in 6-9-year-old urban schoolchildren in the eastern Black Sea region of Turkey.

    Science.gov (United States)

    Orhan, F; Karakas, T; Cakir, M; Aksoy, A; Baki, A; Gedik, Y

    2009-07-01

    The prevalence of adverse reactions to food in childhood in Turkey is not known. We aimed to investigate the prevalence and characteristics of IgE-mediated food allergies (FAs) in 6-9-year-old urban schoolchildren. This cross-sectional study recruited 3500 of the randomly selected 6-9-year-old urban schoolchildren from the eastern Black Sea region of Turkey during 2006. Following a self-administered questionnaire completed by the parents and the child, consenting children were invited for skin prick tests (SPTs) and oral food challenges. Children with suspected IgE-mediated FA were skin prick tested with a predefined panel of food allergens (milk, hen's egg, soy, wheat, peanut, fish, and hazelnut), aeroallergens (Dermatophagoides pteronyssinus, Dermatophagoides farinae, cat, dog, Alternaria, grass pollen mix, weed pollen mix, and tree pollen mix), and food allergens reported in the questionnaire. All children with a positive SPT to any food were invited for a double-blind, placebo-controlled food challenge (DBPCFC). The prevalence of IgE-mediated FA was established using DBPCFCs. The response rate to the questionnaire was 78.2% (2739/3500). The estimated prevalence of parental-reported IgE-mediated FA was 5.7% (156/2739) [95% confidence interval (CI), 4.83-6.57%]. The rate of sensitization to the food allergens was 33.1% (48/145) in the parental-reported group. The confirmed prevalence of IgE-mediated FA by means of DBPCFC in 6-9-year-old urban schoolchildren living in the eastern Black Sea region of Turkey was 0.80% (22/2739) (95% CI, 0.47-1.13%). The most common allergenic foods were beef (31.8%), cow's milk (18.1%), cocoa (18.1%), hen's egg (13.6%), and kiwi (13.6%). The rate of reported IgE-mediated FA was significantly higher than clinically confirmed FA by means of DBPCFC (odds ratio, 7.46; 95% CI, 4.67-12.01; Pfoods was different and somewhat unique to the eastern Black Sea region of Turkey when compared with western countries.

  19. Aerosol modelling for regional climate studies: application to anthropogenic particles and evaluation over a European/African domain

    International Nuclear Information System (INIS)

    Solmon, F.; Giorgi, F.; Liousse, C.

    2006-01-01

    A simplified anthropogenic aerosol model for use in climate studies is developed and implemented within the regional climate model RegCM. The model includes sulphur dioxide, sulphate, hydrophobic and hydrophilic black carbon (BC) and organic carbon (OC) and is run for the winter and summer seasons of 2000 over a large domain extending from northern Europe to south tropical Africa. An evaluation of the model performance is carried out in terms of surface concentrations and aerosol optical depths (AODs). For sulphur dioxide and sulphate concentration, comparison of simulated fields and experimental data collected over the EMEP European network shows that the model generally reproduces the observed spatial patterns of near-surface sulphate. Sulphate concentrations are within a factor of 2 of observations in 34% (JJA) to 57% (DJF) of cases. For OC and BC, simulated concentrations are compared to different datasets. The simulated and observed values agree within a factor of 2 in 56% (DJF) to 62% (JJA) of cases for BC and 33% (JJA) to 64% (DJF) for OC. Simulated AODs are compared with ground-based (AERONET) and satellite (MODIS, MISR, TOMS) AOD datasets. Simulated AODs are in the range of AERONET and MISR data over northern Europe, and AOD spatial patterns show consistency with MODIS and TOMS retrievals both over Europe and Africa. The main model deficiencies we find are: (i) an underestimation of surface concentrations of sulphate and OC during the summer and especially over the Mediterranean region and (ii) a general underestimation of AOD, most pronounced over the Mediterranean basin. The primary factors we identify as contributing to these biases are the lack of natural aerosols (in particular, desert dust, secondary biogenic aerosols and nitrates), uncertainties in the emission inventories and aerosol cycling by moist convection. Also, in view of the availability of better observing datasets (e.g. as part of the AMMA project), we are currently working on improving

  20. Summed Probability Distribution of 14C Dates Suggests Regional Divergences in the Population Dynamics of the Jomon Period in Eastern Japan.

    Directory of Open Access Journals (Sweden)

    Enrico R Crema

    Full Text Available Recent advances in the use of summed probability distribution (SPD of calibrated 14C dates have opened new possibilities for studying prehistoric demography. The degree of correlation between climate change and population dynamics can now be accurately quantified, and divergences in the demographic history of distinct geographic areas can be statistically assessed. Here we contribute to this research agenda by reconstructing the prehistoric population change of Jomon hunter-gatherers between 7,000 and 3,000 cal BP. We collected 1,433 14C dates from three different regions in Eastern Japan (Kanto, Aomori and Hokkaido and established that the observed fluctuations in the SPDs were statistically significant. We also introduced a new non-parametric permutation test for comparing multiple sets of SPDs that highlights point of divergences in the population history of different geographic regions. Our analyses indicate a general rise-and-fall pattern shared by the three regions but also some key regional differences during the 6th millennium cal BP. The results confirm some of the patterns suggested by previous archaeological studies based on house and site counts but offer statistical significance and an absolute chronological framework that will enable future studies aiming to establish potential correlation with climatic changes.

  1. Removing Regional Trends in Microgravity in Complex Environments: Testing on 3D Model and Field Investigations in the Eastern Dead Sea Coast (Jordan

    Directory of Open Access Journals (Sweden)

    A. Al-Zoubi

    2013-01-01

    Full Text Available Microgravity investigations are now recognized as a powerful tool for subsurface imaging and especially for the localization of underground karsts. However numerous natural (geological, technical, and environmental factors interfere with microgravity survey processing and interpretation. One of natural factors that causes the most disturbance in complex geological environments is the influence of regional trends. In the Dead Sea coastal areas the influence of regional trends can exceed residual gravity effects by some tenfold. Many widely applied methods are unable to remove regional trends with sufficient accuracy. We tested number of transformation methods (including computing gravity field derivatives, self-adjusting and adaptive filtering, Fourier series, wavelet, and other procedures on a 3D model (complicated by randomly distributed noise, and field investigations were carried out in Ghor Al-Haditha (the eastern side of the Dead Sea in Jordan. We show that the most effective methods for regional trend removal (at least for the theoretical and field cases here are the bilinear saddle and local polynomial regressions. Application of these methods made it possible to detect the anomalous gravity effect from buried targets in the theoretical model and to extract the local gravity anomaly at the Ghor Al-Haditha site. The local anomaly was utilized for 3D gravity modeling to construct a physical-geological model (PGM.

  2. Exon organization of the mouse entactin gene corresponds to the structural domains of the polypeptide and has regional homology to the low-density lipoprotein receptor gene

    DEFF Research Database (Denmark)

    Durkin, M E; Wewer, U M; Chung, A E

    1995-01-01

    of the mouse entactin gene closely corresponds to the organization of the polypeptide into distinct structural and functional domains. The two amino-terminal globular domains are encoded by three exons each. Single exons encode the two protease-sensitive, O-glycosylated linking regions. The six EGF......Entactin is a widespread basement membrane protein of 150 kDa that binds to type IV collagen and laminin. The complete exon-intron structure of the mouse entactin gene has been determined from lambda genomic DNA clones. The gene spans at least 65 kb and contains 20 exons. The exon organization...

  3. Feeding ecology and nutrition of an eastern gorilla group in the Mt. Kahuzi Region (République du Zaïre).

    Science.gov (United States)

    Casimir, M J

    1975-01-01

    An eastern gorilla group of the Mt. Kahuzi region (République du Zaïre) was studied over 15 months. Its migration route was determined, and the various biotopes it visited are described. A record was made of its main food plants, and of the plant parts eaten. For nine important food plants the protein content, the concentration of the individual amino acids and the water content were measured for the plant parts eaten and for those not eaten. For some of these plant parts the Na, K, Ca and Mg content were also determined. No general correlation between food selection and one or several of these factors could be found. The development and value of a traditionally determined mixed diet is discussed.

  4. Application Self-organizing Map Type in a Study of the Profile of Gasoline C Commercialized in the Eastern and Northern Parana Regions

    Directory of Open Access Journals (Sweden)

    Lívia Ramazzoti Silva

    2015-06-01

    Full Text Available Artificial neural networks self-organizing map type (SOM was used to classify samples of automotive gasoline C marketed in the eastern and northern regions of the state of Paraná, Brazil. The input order of parameters in the network were the values of temperature of the first drop, the 10, 50 and 90% distilled bulk, the final boiling point, density, residue content and alcohol content. A network with a topology of 25x25 and 5000 training epochs was used. The weight maps of input parameters for the trained network identified that the most important parameters for classifying samples were the temperature of the first drop and the temperature of the 10% and 50% of the distilled fuel. DOI: http://dx.doi.org/10.17807/orbital.v7i2.732 

  5. Inter-annual rainfall variability in the eastern Antilles and coupling with the regional and intra-seasonal circulation

    Science.gov (United States)

    Jury, Mark R.

    2016-11-01

    Climate variability in the eastern Antilles island chain is analyzed via principal component analysis of high-resolution monthly rainfall in the period 1981-2013. The second mode reflecting higher rainfall in July-October season between Martinique and Grenada is the focus of this study. Higher rainfall corresponds with a weakened trade wind and boundary current along the southern edge of the Caribbean. This quells the coastal upwelling off Venezuela and builds the freshwater plume east of Trinidad. There is corresponding upper easterly wind flow that intensifies passing tropical waves. During a storm event over the Antilles on 4-5 October 2010, there was inflow from east of Guyana where low salinity and high sea temperatures enable surplus latent heat fluxes. A N-S convective rain band forms ˜500 km east of the cyclonic vortex. Many features at the weather timescale reflect the seasonal correlation and composite difference maps and El Nino Southern Oscillation (ENSO) modulation of oceanic inter-basin transfers.

  6. Dynamic simulation for wastewater treatment plants management: Case of Souk-Ahras region, north-eastern Algeria

    Directory of Open Access Journals (Sweden)

    Sabri Dairi

    2017-09-01

    Full Text Available Treatment performances of two wastewater treatment plants (WWTPs, located in North-Eastern Algeria (Souk-Ahras and Sedrata were tested using ASM1 model. The model, to be considered as a decision tool for the appropriate management of activated sludge systems, served for the prediction of both WWTP behaviours under different operating conditions. In Sedrata WWTP the first management scenarios is based on an increase of inflow rate, taking into account a new transfer volume from a nearby zone. In a second scenerio, the ultimate flow of 40 000 m3·d-1 is estimated. Regarding Souk-Ahras WWTP, three scenarios were tested. The first tested the impact of an increase of the extraction flow rate and yielded a reduction by 37% of sludge production. The second dealt with the management of the mass budget of substrata and biomass. Finally, the third application was devoted to the estimation of the plant ultimate capacity, estimated to be 60 000 m3·d-1.

  7. Mycoplasma bovis infections and co-infections with other Mycoplasma spp. with different clinical manifestations in affected cattle herds in eastern region of Poland

    Directory of Open Access Journals (Sweden)

    Szacawa Ewelina

    2015-09-01

    Full Text Available The aim of the study was to evaluate the presence of Mycoplasma bovis infection and co-infections with other Mycoplasma spp. infections in cattle. The tested population was one in the eastern region of Poland containing 66 dairy cows and 23 calves showing different clinical signs and suffering from pneumonia, mastitis, and arthritis. The incidence of M. bovis in co-infections with other Mycoplasma spp. was examined using serological traditional mycoplasma culture methods, and the molecular methods - PCR and polymerase chain reaction/denaturing gradient gel electrophoresis (PCR/DGGE. The PCR/DGGE method for detecting Mycoplasma spp. in cattle was used for the first time in Poland. The seroprevalence of M. bovis in the affected cattle herds in the eastern region of Poland was 47.8% in calves and 19.7% in dairy cows. The direct detection and identification of M. bovis from nasopharyngeal swabs by PCR revealed that 56.5% of calves were positive, but all of the dairy cows were negative. The PCR/DGGE identified eight (34.8% instances of M. arginini and eight (26.1% instances of M. bovirhinis co-infecting with M. bovis in ten calves. The seroprevalence of M. bovis in the tested population was 33.7%. Any future attempts to control mycoplasma infections require an insight into the current epidemiological situation of M. bovis infection and its relationship to other mycoplasmas in causing clinical disease in cattle. Using these diagnostic methods we have demonstrated that mycoplasmal infections are often caused by multiple species of Mycoplasma and not just the primary M. bovis pathogen.

  8. OPERATIONAL REMOTE SENSING SERVICES IN NORTH EASTERN REGION OF INDIA FOR NATURAL RESOURCES MANAGEMENT, EARLY WARNING FOR DISASTER RISK REDUCTION AND DISSEMINATION OF INFORMATION AND SERVICES

    Directory of Open Access Journals (Sweden)

    P. L. N. Raju

    2016-06-01

    Full Text Available North Eastern Region (NER of India comprising of eight states considered to be most unique and one of the most challenging regions to govern due to its unique physiographic condition, rich biodiversity, disaster prone and diverse socio-economic characteristics. Operational Remote Sensing services increased manifolds in the region with the establishment of North Eastern Space Applications Centre (NESAC in the year 2000. Since inception, NESAC has been providing remote sensing services in generating inventory, planning and developmental activities, and management of natural resources, disasters and dissemination of information and services through geo-web services for NER. The operational remote sensing services provided by NESAC can be broadly divided into three categories viz. natural resource planning and developmental services, disaster risk reduction and early warning services and information dissemination through geo-portal services. As a apart of natural resources planning and developmental services NESAC supports the state forest departments in preparing the forest working plans by providing geospatial inputs covering entire NER, identifying the suitable culturable wastelands for cultivation of silkworm food plants, mapping of natural resources such as land use/land cover, wastelands, land degradation etc. on temporal basis. In the area of disaster risk reduction, NESAC has initiated operational services for early warning and post disaster assessment inputs for flood early warning system (FLEWS using satellite remote sensing, numerical weather prediction, hydrological modeling etc.; forest fire alert system with actionable attribute information; Japanese Encephalitis Early Warning System (JEWS based on mosquito vector abundance, pig population and historical disease intensity and agriculture drought monitoring for the region. The large volumes of geo-spatial databases generated as part of operational services are made available to the

  9. Operational Remote Sensing Services in North Eastern Region of India for Natural Resources Management, Early Warning for Disaster Risk Reduction and Dissemination of Information and Services

    Science.gov (United States)

    Raju, P. L. N.; Sarma, K. K.; Barman, D.; Handique, B. K.; Chutia, D.; Kundu, S. S.; Das, R. Kr.; Chakraborty, K.; Das, R.; Goswami, J.; Das, P.; Devi, H. S.; Nongkynrih, J. M.; Bhusan, K.; Singh, M. S.; Singh, P. S.; Saikhom, V.; Goswami, C.; Pebam, R.; Borgohain, A.; Gogoi, R. B.; Singh, N. R.; Bharali, A.; Sarma, D.; Lyngdoh, R. B.; Mandal, P. P.; Chabukdhara, M.

    2016-06-01

    North Eastern Region (NER) of India comprising of eight states considered to be most unique and one of the most challenging regions to govern due to its unique physiographic condition, rich biodiversity, disaster prone and diverse socio-economic characteristics. Operational Remote Sensing services increased manifolds in the region with the establishment of North Eastern Space Applications Centre (NESAC) in the year 2000. Since inception, NESAC has been providing remote sensing services in generating inventory, planning and developmental activities, and management of natural resources, disasters and dissemination of information and services through geo-web services for NER. The operational remote sensing services provided by NESAC can be broadly divided into three categories viz. natural resource planning and developmental services, disaster risk reduction and early warning services and information dissemination through geo-portal services. As a apart of natural resources planning and developmental services NESAC supports the state forest departments in preparing the forest working plans by providing geospatial inputs covering entire NER, identifying the suitable culturable wastelands for cultivation of silkworm food plants, mapping of natural resources such as land use/land cover, wastelands, land degradation etc. on temporal basis. In the area of disaster risk reduction, NESAC has initiated operational services for early warning and post disaster assessment inputs for flood early warning system (FLEWS) using satellite remote sensing, numerical weather prediction, hydrological modeling etc.; forest fire alert system with actionable attribute information; Japanese Encephalitis Early Warning System (JEWS) based on mosquito vector abundance, pig population and historical disease intensity and agriculture drought monitoring for the region. The large volumes of geo-spatial databases generated as part of operational services are made available to the administrators and

  10. Regional intensity-duration-frequency analysis in the Eastern Black Sea Basin, Turkey, by using L-moments and regression analysis

    Science.gov (United States)

    Ghiaei, Farhad; Kankal, Murat; Anilan, Tugce; Yuksek, Omer

    2018-01-01

    The analysis of rainfall frequency is an important step in hydrology and water resources engineering. However, a lack of measuring stations, short duration of statistical periods, and unreliable outliers are among the most important problems when designing hydrology projects. In this study, regional rainfall analysis based on L-moments was used to overcome these problems in the Eastern Black Sea Basin (EBSB) of Turkey. The L-moments technique was applied at all stages of the regional analysis, including determining homogeneous regions, in addition to fitting and estimating parameters from appropriate distribution functions in each homogeneous region. We studied annual maximum rainfall height values of various durations (5 min to 24 h) from seven rain gauge stations located in the EBSB in Turkey, which have gauging periods of 39 to 70 years. Homogeneity of the region was evaluated by using L-moments. The goodness-of-fit criterion for each distribution was defined as the ZDIST statistics, depending on various distributions, including generalized logistic (GLO), generalized extreme value (GEV), generalized normal (GNO), Pearson type 3 (PE3), and generalized Pareto (GPA). GLO and GEV determined the best distributions for short (5 to 30 min) and long (1 to 24 h) period data, respectively. Based on the distribution functions, the governing equations were extracted for calculation of intensities of 2, 5, 25, 50, 100, 250, and 500 years return periods (T). Subsequently, the T values for different rainfall intensities were estimated using data quantifying maximum amount of rainfall at different times. Using these T values, duration, altitude, latitude, and longitude values were used as independent variables in a regression model of the data. The determination coefficient ( R 2) value indicated that the model yields suitable results for the regional relationship of intensity-duration-frequency (IDF), which is necessary for the design of hydraulic structures in small and

  11. SagE induces highly effective protective immunity against Streptococcus iniae mainly through an immunogenic domain in the extracellular region.

    Science.gov (United States)

    Sun, Yun; Sun, Li; Xing, Ming-qing; Liu, Chun-sheng; Hu, Yong-hua

    2013-11-12

    Streptococcus iniae is a Gram-positive bacterium and a severe pathogen of a wide range of farmed fish. S. iniae possesses a virulence-associated streptolysin S cluster composed of several components, one of which is SagE. SagE a transmembrane protein with one major extracellular region named ECR. This study aimed to develop a SagE-based DNA candidate vaccine against streptococcosis and examine the immunoprotective mechanism of the vaccine. We constructed a DNA vaccine, pSagE, based on the sagE gene and examined its immunological property in a Japanese flounder (Paralichthys olivaceus) model. The results showed that at 7 days post-vaccination, expression of SagE at transcription and translation levels was detected in the tissues of the vaccinated fish. After challenge with S. iniae at one and two months post-vaccination, pSagE-vaccinated fish exhibited relative percent survival (RPS) of 95% and 88% respectively. Immunological analysis showed that (i) pSagE significantly upregulated the expression of a wide range of immune genes, (ii) pSagE induced the production of specific serum antibodies that bound whole-cell S. iniae, and (iii) treatment of S. iniae with pSagE-induced antibodies blocked bacterial invasion of host cells. To localize the immunoprotective domain of SagE, the ECR-expressing DNA vaccine pSagEECR was constructed. Immunization analysis showed that flounder vaccinated with pSagEECR exhibited a RPS of 68%, and that pSagEECR induced serum antibody production and immune gene expression in a manner similar to, though to lower magnitudes than, those induced by pSagE. We in this study developed a DNA vaccine, pSagE, which induces highly protective immunity against S. iniae. The protective effect of pSagE is probably due to its ability to elicit systemic immune response, in particular that of the humoral branch, which leads to production of specific serum antibodies that impair bacterial infection. These results add insights to the immunoprotective mechanism

  12. Low temperature thermochronology and topographic evolution of the South Atlantic passive continental margin in the region in eastern Argentina

    Science.gov (United States)

    Pfister, Sabrina; Kollenz, Sebastian; Glasmacher, Ulrich A.

    2014-05-01

    To understand the evolution of the passive continental margin in Argentina low temperature thermochronology is an appropriate method, which will lead to new conclusions in this area. The Tandilia System, also called Sierras Septentrionales, is located south of the Río de la Plato Craton in eastern Argentina in the state of Buenos Aires. North of the hills Salado basin is located whereas the Claromecó basin is situated south of the mountain range. In contrary to most basins along the southamerican passive continental margin the Tandilia-System and the neighbouring basins trend perpendicular to the coast line. The topography is fairly flat with altitudes of. The igneous-metamorphic basement is pre-proterozoic in age and build up of mainly granitic-tonalitic gneisses, migmatites, amphibolites, some ultramafic rocks and granitoid plutons it is overlain by a series of Neoproterozoic to early Paleozoic sediments (Cingolani, 2010), like siliciclastics, dolostones, shales and limestones (Demoulin et al., 2005). The aim of the study is to quantify the long-term landscape evolution of the passive continental margin in eastern Argentina in terms of thermal history, exhumation and tectonic activities. For that purpose, samples were taken from the Sierra Septentrionales and analyzed with the apatite fission-track method. Further 2-D thermokinematic modeling was conducted with the computer code HeFTy (Ketcham, 2005; Ketcham 2007; Ketcham et al., 2009). The results indicate apatite fission track ages between 101.6 (9.4) to 228.9 (22.3) Ma, what means all measured ages are younger as their formation age. That shows all samples have been reset. Six samples accomplished enough confined tracks and were used to test geological t-T models against the AFT data set. These models give a more detailed insight on the cooling history and tectonic activities in the research area. References: Cingolani C. A. (2010): The Tandilia System of Argentina as a southern extension of the Río de la

  13. Water quality impact assessment of agricultural Beneficial Management Practices (BMPs) simulated for a regional catchment in Quebec, Eastern Canada

    Science.gov (United States)

    Rousseau, Alain N.; Hallema, Dennis W.; Gumiere, Silvio J.; Savary, Stéphane; Hould Gosselin, Gabriel

    2014-05-01

    Water quality has become a matter of increasing concern over the past four decades as a result of the intensification of agriculture, and more particularly so in Canada where agriculture has evolved into the largest non-point source of surface water pollution. The Canadian WEBs project (Watershed Evaluation of Beneficial Management Practices, BMPs) was initiated in order to determine the efficiency of BMPs in improving the surface water quality of rural catchments, and the economic aspects related to their implementation on the same scale. In this contribution we use the integrated watershed modelling platform GIBSI (Gestion Intégrée des Bassins versants à l'aide d'un Système Informatisé) to evaluate the effects of various BMPs on sediment and nutrient yields and, in close relation to this, the surface water quality for the Beaurivage River catchment (718 km2) in Quebec, eastern Canada. A base scenario of the catchment is developed by calibrating the different models of the GIBSI platform, namely HYDROTEL for hydrology, the Revised Universal Soil Loss Equation (RUSLE) for soil erosion, the Erosion-Productivity Impact Calculator (EPIC) of the Soil and Water Assessment Tool (SWAT) for contaminant transport and fate, and QUAL2E for stream water quality. Four BMPs were analysed: (1) vegetated riparian buffer strips, (2) precision slurry application, (3) transition of all cereal and corn fields to grassland (grassland conversion), and (4) no-tillage on corn fields. Simulations suggest that riparian buffer strips and grassland conversion are more effective in terms of phosphorus, nitrogen and sediment load reduction than precision slurry application and no-tillage on corn fields. The results furthermore indicate the need for a more profound understanding of sediment dynamics in streams and on riparian buffer strips.

  14. Western blot banding pattern in early Lyme borreliosis among patients from an endemic region of north-eastern Poland.

    Science.gov (United States)

    Flisiak, R; Wierzbicka, I; Prokopowicz, D

    1998-01-01

    Aim of this study was evaluation of Western blot banding patterns in different clinical forms of early Lyme borreliosis diagnosed in patients from north-eastern Poland, recognized as endemic for tick-borne diseases. Study was performed on serum samples of 48 patients with Lyme borreliosis and 26 healthy volunteers, as controls. Samples tested routinely for total antibody with enzyme immunoassay were subsequently analysed for specific antibodies with Western blot based on antigen extract of European strain of Borrelia burgdorferi. In patients, IgM antibodies were the most frequently directed against 41 kDa and 58 kDa antigens, whereas in control group only antibodies against 45 kDa and 58 kDa were present. Similar response was observed in respect to IgG antibodies. Evaluation of banding pattern in respect to clinical form of the disease revealed the highest prevalence of IgM and IgG anti-41 kDa antibodies in patients with erythema migrans and Lyme arthritis, and anti-58 kDa in neuroborreliosis patients, who had no anti-21 kDa antibodies. Relatively high frequency of IgG antibodies against 21, 30 and 93 kDa antigens was typical for neuroborreliosis. Bands count was significantly higher in different clinical forms of the disease than in controls, and it was the highest in neuroborreliosis. Combined analysis of Western blot results (IgM/IgG) enabled to achieve higher sensitivity (84%) and specificity (100%) than available with the most recommended EIA kits.

  15. Detection of blaOXA-23-like and blaNDM-1 in Acinetobacter baumannii from the Eastern Region, Saudi Arabia.

    Science.gov (United States)

    El-Mahdy, Taghrid S; Al-Agamy, Mohamed H; Al-Qahtani, Ahmed A; Shibl, Atef M

    2017-01-01

    Acinetobacter baumannii is currently considered as one of the most common successful pathogens in the healthcare system due to its ability to quickly develop resistance. Ten carbapenem-resistant A. calcoaceticus-baumannii complex were isolated from the eastern region, Saudi Arabia in 2014. All isolates were resistant to ciprofloxacin, however, 8 of 10 isolates were tigecycline resistant. Susceptibility test was also carried out for three aminoglycosides, resistance to gentamicin was 80%, amikacin was 90%, and tobramycin was 50%. Colistin susceptibility was seen in all isolates. The 10 isolates harbored bla OXA-23-like and ISAba1 and 9 of them also carried bla ADC . Three isolates of 10 harbored bla NDM-1 coding for NDM metallo-β-lactamase (MBL) with coexistence of bla ADC together with either bla GES or bla TEM or both. Those three isolates exhibited negative Etest MBL screening test. Pulsed-field gel electrophoresis revealed the high clonal variability of the isolates, although two isolates were indistinguishable. The risk of dissemination of carbapenem resistance through presence of ISAba1 upstream of OXA-23-like in all isolates raises the concern about emergence of higher carbapenem prevalence rates in the future in our region. This study also demonstrated the importance of molecular surveillance to provide accurate and reliable data about the resistance rates of A. baumannii. Finally, the high incidence of NDM-1 among our isolates requires a routine surveillance to monitor the future prevalence of this enzyme in the region.

  16. Increasing salinity drastically reduces hatching success of crustaceans from depression wetlands of the semi-arid Eastern Cape Karoo region, South Africa.

    Science.gov (United States)

    Mabidi, Annah; Bird, Matthew S; Perissinotto, Renzo

    2018-04-13

    Salinity is an important factor affecting freshwater aquatic species distribution and diversity. The semi-arid Eastern Cape Karoo region of South Africa has been earmarked for shale gas development through hydraulic fracturing. The process uses large amounts of water and produces briny wastewater. When not managed properly, these wastewaters may lead to salinisation of surface freshwater bodies in the region. Therefore, the effect of salinity on the hatching success of crustacean resting eggs was examined using sediments from four depression wetlands found in the region. The sediments were exposed for 28 days to salinity levels of 0.5 g L -1 , 2.5 g L -1 , 5 g L -1 and 10 g L -1 . Control aquaria in which no salt was added were also set up. There was a significant decrease in the emerged taxa richness and abundances at salinities of 2.5 g L -1 and above. Anostraca, Notostraca and Spinicaudata hatchlings were abundant at salinities of 0.5 g L -1 and below, while Copepoda, Daphniidae (Cladocera) and Ostracoda were observed in the highest salinity, but their densities were still lower with increased salinities. Given the importance of large branchiopods in the trophic balance of depression wetlands, their loss may alter the ecological balance and function of these ecosystems.

  17. Isoenzymatic characterization of Phlebotomus ariasi and P. perniciosus of canine leishmaniasis foci from Eastern Pyrenean regions and comparison with other populations from Europe

    Directory of Open Access Journals (Sweden)

    Ballart Cristina

    2018-01-01

    Full Text Available An entomological survey was carried out in 2007 in two Pyrenean counties of Lleida province (north-eastern Spain, where cases of autochthonous canine leishmaniasis have been recently reported. Phlebotomus ariasi and P. perniciosus, vectors of Leishmania infantum in the Mediterranean area, were captured. The aim of the present study was to compare these phlebotomine populations with others captured in known leishmaniasis foci in Europe. Populations of these species were studied by analysing the polymorphism of seven enzymatic systems (HK, PGI, PGM, MDH, 6PGD, FUM and ACO and compared with other specimens from endemic regions of France, Italy, Malta, Portugal and Spain captured in other campaigns, and also with previously published results. Phlebotomus ariasi was more polymorphic than P. perniciosus. Only the ACO locus had diagnostic alleles, but some other alleles show high characteristic frequencies for each species. The neighbour-joining trees separated two population groups in both species. On the basis of the isoenzyme study results, sand fly populations of the Pyrenean region in Lleida province are closely related to those of other nearby leishmaniasis endemic regions in France and Spain.

  18. Regional and temporal variability of melts during a Cordilleran magma pulse: Age and chemical evolution of the jurassic arc, eastern mojave desert, California

    Science.gov (United States)

    Barth, A.P.; Wooden, J.L.; Miller, David; Howard, Keith A.; Fox, Lydia; Schermer, Elizabeth R.; Jacobson, C.E.

    2017-01-01

    Intrusive rock sequences in the central and eastern Mojave Desert segment of the Jurassic Cordilleran arc of the western United States record regional and temporal variations in magmas generated during the second prominent pulse of Mesozoic continental arc magmatism. U/Pb zircon ages provide temporal control for describing variations in rock and zircon geochemistry that reflect differences in magma source components. These source signatures are discernible through mixing and fractionation processes associated with magma ascent and emplacement. The oldest well-dated Jurassic rocks defining initiation of the Jurassic pulse are a 183 Ma monzodiorite and a 181 Ma ignimbrite. Early to Middle Jurassic intrusive rocks comprising the main stage of magmatism include two high-K calc-alkalic groups: to the north, the deformed 183–172 Ma Fort Irwin sequence and contemporaneous rocks in the Granite and Clipper Mountains, and to the south, the 167–164 Ma Bullion sequence. A Late Jurassic suite of shoshonitic, alkali-calcic intrusive rocks, the Bristol Mountains sequence, ranges in age from 164 to 161 Ma and was emplaced as the pulse began to wane. Whole-rock and zircon trace-element geochemistry defines a compositionally coherent Jurassic arc with regional and secular variations in melt compositions. The arc evolved through the magma pulse by progressively greater input of old cratonic crust and lithospheric mantle into the arc magma system, synchronous with progressive regional crustal thickening.

  19. ProteinSplit: splitting of multi-domain proteins using prediction of ordered and disordered regions in protein sequences for virtual structural genomics

    International Nuclear Information System (INIS)

    Wyrwicz, Lucjan S; Koczyk, Grzegorz; Rychlewski, Leszek; Plewczynski, Dariusz

    2007-01-01

    The annotation of protein folds within newly sequenced genomes is the main target for semi-automated protein structure prediction (virtual structural genomics). A large number of automated methods have been developed recently with very good results in the case of single-domain proteins. Unfortunately, most of these automated methods often fail to properly predict the distant homology between a given multi-domain protein query and structural templates. Therefore a multi-domain protein should be split into domains in order to overcome this limitation. ProteinSplit is designed to identify protein domain boundaries using a novel algorithm that predicts disordered regions in protein sequences. The software utilizes various sequence characteristics to assess the local propensity of a protein to be disordered or ordered in terms of local structure stability. These disordered parts of a protein are likely to create interdomain spacers. Because of its speed and portability, the method was successfully applied to several genome-wide fold annotation experiments. The user can run an automated analysis of sets of proteins or perform semi-automated multiple user projects (saving the results on the server). Additionally the sequences of predicted domains can be sent to the Bioinfo.PL Protein Structure Prediction Meta-Server for further protein three-dimensional structure and function prediction. The program is freely accessible as a web service at http://lucjan.bioinfo.pl/proteinsplit together with detailed benchmark results on the critical assessment of a fully automated structure prediction (CAFASP) set of sequences. The source code of the local version of protein domain boundary prediction is available upon request from the authors

  20. Wedding songs’ melodic models of eastern Šumadija and Pomoravlje regions: A contribution to Serbian vocal dialects and identity studies

    Directory of Open Access Journals (Sweden)

    Jovanović Jelena

    2013-01-01

    Full Text Available Extremely complex picture of Šumadija region musical tradition(s could be explained not only as the result of long-lasting encounters and overlapping of different inhabitants’ groups, but also by the fact that in this region even three dialects of Serbian language meet. Moreover, there is a basis for an assumption it is about cultural dialects in wider sense, comprising musical culture as well. Structural-typological analyses of wedding melodic models (glasovi and identifying of their morphological dominants (term coined by V. Maciewskii provided the basis for comparative insight in the elements of vocal tradition in the area in focus – on the first place within wedding genre, but within other genres as well. The cartography technique, applied in melogeographic researches (Goshovskii, provides insight in certain musical phenomena in their territorial dissemination, so that the regularities that could be in direct connection to dialectal features of traditional culture could be seen. The paper is about geographical and cultural space intersected by folklore dialectal borders, and thus it is also the region where the transitory areas between the consistent cultural spaces are placed. This situation has been explained and illustrated through the application of “fuzzy” concept. Musical material from this region and its elements geographic distribution shows it could be about the “fuzzy” border between two cultural and vocal dialects. This paper could be the basis for future research and analyses, including more data from this and surrounding regions, primarily in the East, South and Southeast, which would lead to the differentiating of the musical idiom that characterizes great part of central, Eastern, Southern and Southeastern Serbia. [Projekat Ministarstva nauke Republike Srbije, br. 177004: Identiteti srpske muzike od lokalnih do globalnih okvira: tradicije, promene, izazovi

  1. Regional Contamination of Moravia (South-Eastern Czech Republic): Temporal Shift of Pb and Zn Loading in Fluvial Sediments

    Czech Academy of Sciences Publication Activity Database

    Matys Grygar, Tomáš; Sedláček, J.; Bábek, O.; Nováková, Tereza; Strnad, L.; Mihaljevič, M.

    2012-01-01

    Roč. 223, č. 2 (2012), s. 739-753 ISSN 0049-6979 R&D Projects: GA AV ČR IAAX00130801 Institutional research plan: CEZ:AV0Z40320502 Keywords : fluvial sediments * Pb * Zn * regional contamination Subject RIV: DD - Geochemistry Impact factor: 1.748, year: 2012

  2. Absolute sea levels and isostatic changes of the eastern North Sea to central Baltic region during the last 900 years

    DEFF Research Database (Denmark)

    Hansen, Jens Morten; Aagaard, Troels; Binderup, Merete

    2012-01-01

    that ice-cap growth can be faster than ice-cap melting. By comparison with 29 long-term tide gauge measurements of the region we show that the isostatic implications of the sea-level curve are in nearly perfect agreement with Peltier's global isostatic VM2 model (applied by IPCC and PSMSL) and yield a 3...

  3. Improved analysis of long-term monitoring data demonstrates marked regional declines of bat populations in the eastern United States

    Science.gov (United States)

    Thomas E. Ingersoll; Brent J. Sewall; Sybill K. Amelon

    2013-01-01

    Bats are diverse and ecologically important, but are also subject to a suite of severe threats. Evidence for localized bat mortality from these threats is well-documented in some cases, but long-term changes in regional populations of bats remain poorly understood. Bat hibernation surveys provide an opportunity to improve understanding, but analysis is complicated by...

  4. Differential erosion and the formation of layered yardangs in the Loulan region (Lop Nur), eastern Tarim Basin

    Science.gov (United States)

    Lin, Yongchong; Xu, Lishuai; Mu, Guijin

    2018-02-01

    Yardangs are a type of wind-sculpted landform which generally form in hyper-arid regions. Several factors affect the development of yardangs, and the relative importance of these factors likely varies with differences in regional environmental factors. In the Loulan region of Lop Nur, wind dynamics are the principal factor affecting the development of yardangs. However, layered yardangs, which have undergone a unique form of differential erosion, are common in the region. These erosional landforms differ from typical yardangs which are eroded solely by abrasion and deflation. We conducted field and laboratory investigations of layered yardangs to determine their origin. The results indicate that there are two types of strata comprising the yardangs: uncompacted sand-silt layers, with a lower carbonate content; and compacted clay-silt layers, with a higher carbonate content. Both types of strata are horizontal and occur in alternating layers. This type of structure enables the wind to more easily erode the less resistant sand-silt layers at different heights, leaving the more resistant compacted clay-silt layers relatively intact. Eventually the undercut remnant clay-silt layers collapse once the weight of the suspended strata exceeds their elastic resistance (more than 90% of the fallen blocks have length/thickness ratios between 1.2 and 2.5). Therefore, in addition to wind dynamics, the lithology and structure of the strata are important factors affecting the development of the layered yardangs. This type of differential erosion accelerates the development of the yardangs in the Loulan region.

  5. Regional hardening of Upper Cretaceous Chalk in eastern England, UK: trace element and stable isotope patterns in the Upper Cenomanian and Turonian Chalk and their significance

    Science.gov (United States)

    Jeans, Christopher V.; Long, Dee; Hu, Xiu-Fang; Mortimore, Rory N.

    2014-12-01

    The regional hardening of the Late Cenomanian to Early Turonian Chalk of the Northern Province of eastern England has been investigated by examining the pattern of trace elements and stable carbon and oxygen isotopes in the bulk calcite of two extensive and stratigraphically adjacent units each 4 to 5 m thick of hard chalk in Lincolnshire and Yorkshire. These units are separated by a sequence, 0.3-1.3 m thick, of variegated marls and clayey marls. Modelling of the geochemistry of the hard chalk by comparison with the Standard Louth Chalk, combined with associated petrographic and geological evidence, indicates that (1) the hardening is due to the precipitation of a calcite cement, and (2) the regional and stratigraphical patterns of geochemical variation in the cement are largely independent of each other and have been maintained by the impermeable nature of the thin sequence of the clay-rich marls that separate them. Two phases of calcite cementation are recognised. The first phase was microbially influenced and did not lithify the chalk. It took place predominantly in oxic and suboxic conditions under considerable overpressure in which the Chalk pore fluids circulated within the units, driven by variations in compaction, temperature, pore fluid pressure and local tectonics. There is evidence in central and southern Lincolnshire of the loss of Sr and Mgenriched pore fluids to the south during an early part of this phase. The second phase of calcite precipitation was associated with the loss of overpressure in probably Late Cretaceous and in Cenozoic times as the result of fault movement in the basement penetrating the overlying Chalk and damaging the seal between the two chalk units. This greatly enhanced grain pressures, resulting in grain welding and pressure dissolution, causing lithification with the development of stylolites, marl seams, and brittle fractures. Associated with this loss of overpressure was the penetration of the chalk units by allochthonous

  6. Job satisfaction and associated factors among health care providers at public health institutions in Harari region, eastern Ethiopia: a cross-sectional study.

    Science.gov (United States)

    Geleto, Ayele; Baraki, Negga; Atomsa, Gudina Egata; Dessie, Yadeta

    2015-09-01

    Human factor is the primary resource of health care system. For optimal performance of health care system, the workforce needs to be satisfied with the job he/she is doing. This research was aimed to assess the level of job satisfaction and associated factors among health care providers at public health institutions in Harari region, Eastern Ethiopia. Health facility based cross-sectional study was conducted among 405 randomly selected health care providers in Harari regional state, Eastern Ethiopia. Data were collected by self-administered structured questionnaires. Epidata Version 3.1 was used for data entry and analysis was made with SPSS version 17. Level of job satisfaction was measured with a multi item scales derived from Wellness Council of America and Best Companies Group. The average/mean value was used as the cutoff point to determine whether the respondents were satisfied with their job or not. Multivariable logistic regression was used to analyze data and odds ratio with 95% CI at P ≤ 0.05 was used to identify associated factors with level of job satisfaction. Less than half 179 (44.2%) of the respondents were satisfied with their job. Being midwifery in profession [AOR = 1.20; 95% CI (1.11-2.23)], age less than 35 years [AOR = 2.0; 95% CI (1.67-2.88)], having good attitude to stay in the same ward for longer period [AOR = 3.21; 95 % CI (1.33, 5.41)], and safe working environment [AOR = 4.61; 95% CI (3.33, 6.92)] were found were found to be associated with job satisfaction. Less than half (44.2%) of the respondents were satisfied with their current job. Organizational management system, salary and payment and working environment were among factors that affects level of job satisfaction. Thus, regional health bureau and health facility administrators need to pay special attention to improve management system through the application of a health sector reform strategy.

  7. Tectonic geomorphology and volcano-tectonic interaction in the eastern boundary of the Southern Cascades (Hat Creek Graben region, California, USA

    Directory of Open Access Journals (Sweden)

    Engielle Mae Raot-raot Paguican

    2016-07-01

    Full Text Available The eastern boundary of the Southern Cascades (Hat Creek Graben region, California, USA, is an extensively faulted volcanic corridor between the Cascade Range and Modoc Plateau. The east-west extending region is in the transition zone between the convergence and subduction of the Gorda Plate underneath the North American Plate; north-south shortening within the Klamath Mountain region; and transcurrent movement in the Walker Lane. We describe the geomorphological and tectonic features, their alignment and distribution, in order to understand the tectonic geomorphology and volcano-tectonic relationships. One outcome of the work is a more refined morpho-structural description that will affect future hazard assessment in the area.A database of volcanic centers and structures was created from interpretations of topographic models generated from satellite images. Volcanic centers in the region were classified by morphological type into cones, sub-cones, shields and massifs. A second classification by height separated the bigger and smaller edifices and revealed an evolutionary trend. Poisson Nearest Neighbor analysis shows that bigger volcanoes are spatially dispersed while smaller ones are clustered. Using volcano centroid locations, about 90 lineaments consisting of at least three centers within 6km of one another were found, revealing that preferential north-northwest directed pathways control the transport of magma from the source to the surface, consistent with the strikes of the major fault systems. Most of the volcano crater openings are perpendicular to the maximum horizontal stress, expected for extensional environments with dominant normal regional faults. These results imply that the extension of the Hat Creek Graben region and impingement of the Walker Lane is accommodated mostly by extensional faults and partly by the intrusions that formed the volcanoes. Early in the history of a volcano or volcano cluster, melt produced at depth in the

  8. Sedimentation rates in eastern North America reveal strong links between regional climate, depositional environments, and sediment accumulation

    Science.gov (United States)

    Goring, S. J.; McLachlan, J. S.; Jackson, S. T.; Blaauw, M.; Christen, J.; Marlon, J.; Blois, J.; Williams, J. W.

    2011-12-01

    PalEON is a multidisciplinary project that combines paleo and modern ecological data with state-of-the-art statistical and modelling tools to examine the interactions between climate, fire and vegetation during the past two millennia in the northeastern United States. A fundamental challenge for PalEON (and paleo research more broadly) is to improve age modelling to yield more accurate sediment-core chronologies. To address this challenge, we assessed sedimentation rates and their controls for 218 lakes and mires in the northeastern U.S. Sedimentation rates (yr/cm) were calculated from age-depth models, which were obtained from the Neotoma database (www.neotomadb.org) and other contributed pollen records. The age models were recalibrated to IntCal09 and augmented in some cases using biostratigraphic markers (Picea decline, 16 kcal BP - 10.5 kcal BP; Quercus rise, 12 - 9.1 kcal BP; and Alnus decline, 11.5 - 10.6 kcal BP) as described in Blois et al. (2011). Relationships between sedimentation rates and sediment age, site longitude, and depositional environment (lacustrine or mire) are significant but weak. There are clear and significant links between variations in the NGRIP record of δ18O and sedimentation in mires across the PalEON region, but no links to lacustrine sedimentation rates. This result indicates that super-regional climatic control of primary productivity, and thus autochthonic sediment deposition, dominates in mires while deposition in lacustrine basins may be driven primarily by local and regional factors including watershed size, surficial materials,and regional vegetation. The shape of the gamma probability functions that best describe sedimentation rate distributions are calculated and presented here for use as priors in Bayesian age modelling applications such as BACON (Blaauw and Christen, in press). Future applications of this research are also discussed.

  9. IAEA laboratory activities. The IAEA laboratories at Vienna and Seibersdorf, the International Laboratory of Marine Radioactivity at Monaco, the International Centre for Theoretical Physics at Trieste, the Middle Eastern Regional Radioisotope Centre for the Arab Countries, Cairo. 3rd report

    International Nuclear Information System (INIS)

    1966-01-01

    This third 'IAEA Laboratory Activities' report describes development and work during the year 1965. It includes activities of the IAEA Laboratories at Vienna and Seibersdorf, the International Laboratory of Marine Radioactivity at Monaco, the International Centre for Theoretical Physics at Trieste, and the Middle Eastern Regional Radioisotope Centre for the Arab Countries at Cairo

  10. Agreement for the Establishment in Cairo of a Middle Eastern Regional Radioisotope Centre for the Arab Countries. Acceptances of the Agreement and Pledges of Additional Contributions to the Centre. Information Received up to 31 December 1963

    International Nuclear Information System (INIS)

    1964-01-01

    The Government of the United Arab Republic, the Host State of the Middle Eastern Regional Radioisotope Centre for the Arab Countries, has notified the Agency that on the dates shown the following Arab States deposited with the Government instruments of acceptance of the Agreement establishing the Centre

  11. IAEA Laboratory activities. The IAEA Laboratories at Vienna and Seibersdorf, the International Laboratory of Marine Radioactivity at Monaco, the International Centre for Theoretical Physics at Trieste, the Middle Eastern Regional Radioisotope Centre for the Arab Countries, Cairo. Sixth report

    International Nuclear Information System (INIS)

    1969-01-01

    This sixth 'IAEA Laboratory Activities' report describes development and work during the year 1968. It includes activities of the IAEA Laboratories at Vienna and Seibersdorf, the International Laboratory of Marine Radioactivity at Monaco, the International Centre for Theoretical Physics at Trieste, and the Middle Eastern Regional Radioisotope Centre for the Arab Countries at Cairo. (author)

  12. IAEA Laboratory activities. The IAEA Laboratories at Vienna and Seibersdorf, the International Laboratory of Marine Radioactivity at Monaco, the International Centre for Theoretical Physics at Trieste, the Middle Eastern Regional Radioisotope Centre for the Arab Countries, Cairo. Fourth report

    International Nuclear Information System (INIS)

    1967-01-01

    This fourth 'IAEA Laboratory Activities' report describes development and work during the year 1966. It includes activities of the IAEA Laboratories at Vienna and Seibersdorf, the International Laboratory of Marine Radioactivity at Monaco, the International Centre for Theoretical Physics at Trieste, and the Middle Eastern Regional Radioisotope Centre for the Arab Countries at Cairo. (author)

  13. Domains and domain loss

    DEFF Research Database (Denmark)

    Haberland, Hartmut

    2005-01-01

    politicians and in the media, especially in the discussion whether some languages undergo ‘domain loss’ vis-à-vis powerful international languages like English. An objection that has been raised here is that domains, as originally conceived, are parameters of language choice and not properties of languages...

  14. THE ANALYSIS OF DIFFERENCES IN DOCTORS PREFERENCES IN THE PRESCRIPTIONS OF ANTIHYPERTENSIVE DRUGS IN FOUR REGIONS OF THE FAR EASTERN FEDERAL DISTRICT

    Directory of Open Access Journals (Sweden)

    M. S. Soboleva

    2018-01-01

    Full Text Available Aim. To study regional features and preferences of specialists in the choice of drug therapy of arterial hypertension in four subjects of the Far Eastern Federal District.Material and methods. Statistical data, demographic indicators, state and municipal drug procurements in Chukotka Autonomous Okrug, the Sakha Republic (Yakutia, the Magadan Region, and Kamchatka Krai were analyzed. The studied period was 2012-2016. Dynamics of the use (procurements of five main therapeutic classes of antihypertensive drugs was studied.Results. Among β-blockers the leaders were metoprolol (from 2% to 30.8% and bisoprolol (from 2.4% to 20.3%, in group of angiotensin converting enzyme inhibitors – enalapril (from 3.6% to 27%, lisinopril (from 4.4% to 23.9% and perindopril (from 0.9% to 7.8%, among calcium channel blockers – amlodipine (from 5.6% to 11.3%, in group of diuretics – indapamide (from 2.5% to 13% and spironolactone (from 3% to 12.5%, and in group of angiotensin II antagonists – losartan (from 0.4% to 15.6%. Angiotensin converting enzyme inhibitors were the most used therapeutic class of antihypertensive drugs in Chukotka Autonomous Okrug, the Magadan region and Kamchatka Krai. At the same time, β-blockers accounted for more than a half of state and municipal procurements in the Sakha Republic (Yakutia.Conclusion. It is necessary to study regional aspects and approaches to therapy to assess the extent and specificity of the implementation of research results, standards and recommendations in real clinical practice.

  15. [INCIDENCE, PREDISPOSING RISK FACTORS FOR THE DEVELOPMENT AND SPREADING OF ACUTE INTESTINAL INFECTIONS IN THE NORTH-EASTERN REGION OF UKRAINE].

    Science.gov (United States)

    Malysh, N G; Chemych, N D; Zaritsky, A M

    2016-01-01

    Using data of the branch statistical reporting of the State Sanitary and Epidemiological Service in Sumy region and Sumy Regional State Laboratory of Veterinary Medicine, the incidence rate, modern risk factors for the development and spreading of acute infectious diarrheas were determined in the North-Eastern region of Ukraine. Under the current conditions incidence rate indices of acute intestinal infections and food toxicoinfections are within the range of 159.8-193.6 per 100 thousands. pop. Seasonal and epidemical rises are associated with a species of the agent. In the etiological structure of acute diarrheal infections there are dominated viruses, of food toxicoinfections--Klebsiellae pneumoniae, Staphylococcus aureus and Enterobacter cloacae (p < 0.05). Predictors of the complication of epidemiological situation of Shigella infections are the gain in the detection of bacterially contaminated samples of milk and dairy products (r = 0.75), for food toxicoinfections caused by Klebsiellae pneumoniae and Enterobacter cloacae--pastry with cream and cooking meat products (r = 0.64; r = 0.75). Epizootic situation in the region affects on the salmonellosis incidence rate of the population (r = 0.89). There were revealed correlations between the selection of E. coli bacteria from swabs taken from the enterprises of catering, in child care centers and the levels of incidence rates of salmonellosis, acute intestinal infections of unknown etiology (r = 0.59; r = 0.60). Timely detection and sanitation of Shigella carriers are a powerful instrument to reduce the incidence rate of shigellosis (r = 0.83).

  16. Universal salt iodization in the Central and Eastern Europe, Commonwealth of Independent States (CEE/CIS) Region during the decade 2000-09: experiences, achievements, and lessons learned.

    Science.gov (United States)

    van der Haar, Frits; Gerasimov, Gregory; Tyler, Vilma Qahoush; Timmer, Arnold

    2011-12-01

    By 2000, the global track record on universal salt iodization (USI) indicated 26% access to adequately iodized salt in the Central and Eastern Europe, Commonwealth of Independent States (CEE/ CIS) Region. Aimed at extracting lessons learned, this study examined experiences, achievements, and outcomes of USI strategies in CEE/CIS countries during the subsequent decade. Information from the design, timing, execution, outputs, multi-sector management and results of actions by national stakeholders yielded 20 country summaries. Analysis across countries used a LogFrame Analysis typical for public nutrition development. By 2009, USI strategies had reached the target and population iodine nutrition shown adequate levels in 9 countries, while in 6 others, USI was close and/or population iodine status showed only minor imperfection. True USI, i.e., iodization of salt destined both for the food industry and the household, had been made mandatory in 13 of these 15 countries. In the Balkan area, USI and iodine nutrition advanced more than in CIS. Of the 20 sample countries, 17 (85%) had exceeded the mark of 50% adequate access, while the overall regional score reached 55% by 2010. Experience from this region suggests that strong partnership collaboration, a new concept in post-Soviet societies, was a major success factor. Voluntary iodization or focusing on household salt alone was less likely conducive for success. Achieving optimum iodine nutrition required the setting of proper iodine standard Weak political leadership insistence in the Russian Federation and Ukraine to embrace USI is the main factor why the region remains behind in the global progress.

  17. Morphological correlates of prey consumed by Podarcis melisellensis (Braun, 1877 and P. siculus (Rafinesque, 1810 (Sauria, Lacertidae from two mainland regions in the eastern Adriatic area

    Directory of Open Access Journals (Sweden)

    Stamenković S.Ž.

    2013-01-01

    Full Text Available The correlation between trophic utilization and morphology was studied for two lizard species (Podarcis melisellensis and P. siculus from two mainland localities in the eastern Adriatic area; this is the first report of trophic and morphometric data for P. melisellensis from mainland populations. Variance partitioning showed that most of the variation in morphological traits for the analyzed lizards was the result of differences between species, and to a lesser extent between sexes. Locality did not have a strong effect on the variation of morphological traits. Prey weight is the only characteristic of prey that generally exhibits correlations with morphological characteristics rather than prey size. The pattern of correlations is generally weaker for P. melisellensis than for P. siculus. Optimal foraging theory predictions were generally confirmed: P. siculus is more constrained by trophic resource availability, with a premium on larger and heavier prey consumed in the less productive locality (SM, which can be relaxed in more productive regions (KL. P. melisellensis shows such constraints only for males in the less productive region (SM. Females of both species consume heavier prey. [Projekat Ministarstva nauke Republike Srbije, br. III43001 i br. 173011

  18. Insights into the abundance and diversity of abyssal megafauna in a polymetallic-nodule region in the eastern Clarion-Clipperton Zone.

    Science.gov (United States)

    Amon, Diva J; Ziegler, Amanda F; Dahlgren, Thomas G; Glover, Adrian G; Goineau, Aurélie; Gooday, Andrew J; Wiklund, Helena; Smith, Craig R

    2016-07-29

    There is growing interest in mining polymetallic nodules in the abyssal Clarion-Clipperton Zone (CCZ) in the Pacific. Nonetheless, benthic communities in this region remain poorly known. The ABYSSLINE Project is conducting benthic biological baseline surveys for the UK Seabed Resources Ltd. exploration contract area (UK-1) in the CCZ. Using a Remotely Operated Vehicle, we surveyed megafauna at four sites within a 900 km(2) stratum in the UK-1 contract area, and at a site ~250 km east of the UK-1 area, allowing us to make the first estimates of abundance and diversity. We distinguished 170 morphotypes within the UK-1 contract area but species-richness estimators suggest this could be as high as 229. Megafaunal abundance averaged 1.48 ind. m(-2). Seven of 12 collected metazoan species were new to science, and four belonged to new genera. Approximately half of the morphotypes occurred only on polymetallic nodules. There were weak, but statistically significant, positive correlations between megafaunal and nodule abundance. Eastern-CCZ megafaunal diversity is high relative to two abyssal datasets from other regions, however comparisons with CCZ and DISCOL datasets are problematic given the lack of standardised methods and taxonomy. We postulate that CCZ megafaunal diversity is driven in part by habitat heterogeneity.

  19. Re-examining the Role of Transport Infrastructure in Trade, Regional Growth and Governance: Comparing the Greater Mekong Subregion (GMS and Central Eastern Europe (CEE

    Directory of Open Access Journals (Sweden)

    François Bafoil

    2010-01-01

    Full Text Available The main objective of this article is to question the hypothesis of the role of transport infrastructures in regional economic growth by comparing Central Eastern Europe (supported by the EU structural and cohesion funds and the Greater Mekong Subregion (mainly supported by the “economic corridors” of the ADB. Three main components of trade efficiency are scrutinized and compared: (1 the historical development of trade agreements, (2 the supra-national (regional capacity of trade regulation, and (3 the micro level of governance between the different actors involved in trade. The comparison between CEE and the GMS is all the more warranted because of two paradoxes that need to be explained: The first one results from the existing link between transport and growth in the case of the GMS, and the lack of a link in the case of CEE. The second paradox insists on the fact that despite their very different institutional frameworks, both subregions continue to face similar challenges concerning the implementation of trade agreements and the exchange of facilities at the local level – pointing towards the issue of governance.

  20. Regional impacts of expanding gas-fired electric generation in the Northeast U.S. and Eastern Canada

    International Nuclear Information System (INIS)

    Mitchell, G.K.

    2001-01-01

    For the purpose of this presentation, the author placed emphasis on the northeast United States, including New York, New England, plus Ontario, Quebec and the Maritime provinces in Canada. The entire region comes under the Northeast Power Coordinating Committee (NPCC) of the North American Electric Reliability Council (NERC). The objective of this Council is to assist with the coordination of electric supply as well as transmission planning and reliability of the utilities. The annual ten year forecast of electric supply, demand and fuel sources produced by the NERC formed the basis for the data presented. The deregulation of the electricity market in a few jurisdictions in the region resulted in the break-up of several electric utilities into their core components: generation, distribution and transmission. The generation sector is where the fastest break-up activity is taking place and merchant energy companies are emerging. Each of these merchant energy companies is competing against the other to effect sales into the wholesale power market through the building of at risk generation plants. The deregulation process is subjected to different processes and time tables depending on each state or provincial regulations. The construction of new power plants in the region is being driven by the merchant energy companies. They are building low capital cost and highly efficient natural gas combined-cycle base load plants as well as lower cost and moderately efficient natural gas/oil-fired simple-cycle peaking plants. This activity is mainly restricted to the United States, since hydroelectric power, coal and nuclear power are the main presence in Canada. New England experiences summer peaks while Canada has winter peak electric demand. To optimize intra-regional peak generation capacity sharing, there is an opportunity for the electric industry to move gas by wire, and a number of projects are being developed. It is expected that pipeline expansion will be lower in

  1. Using online database for landslide susceptibility assessment with an example from the Veneto Region (north-eastern Italy).

    Science.gov (United States)

    Floris, Mario; Squarzoni, Cristina; Zorzi, Luca; D'Alpaos, Andrea; Iafelice, Maria

    2010-05-01

    Landslide susceptibility maps describe landslide-prone areas by the spatial correlation between landslides and related factors, derived from different kinds of datasets: geological, geotechnical and geomechanical maps, hydrogeological maps, landslides maps, vector and raster terrain data, real-time inclinometer and pore pressure data. In the last decade, thanks to the increasing use of web-based tools for management, sharing and communication of territorial information, many Web-based Geographical Information Systems (WebGIS) were created by local governments or nations, University and Research Centres. Nowadays there is a strong proliferation of geological WebGIS or GeoBrowser, allowing free download of spatial information. There are global Cartographical Portals that provide a free download of DTM and other vector data related to the whole planet (http://www.webgis.com). At major scale, there are WebGIS regarding entire nation (http://www.agiweb.org), or specific region of a country (http://www.mrt.tas.gov.au), or single municipality (http://sitn.ne.ch/). Moreover, portals managed by local government and academic government (http://turtle.ags.gov.ab.ca/Peace_River/Site/) or by a private agency (http://www.bbt-se.com) are noteworthy. In Italy, the first national projects for the creation of WebGIS and web-based databases begun during the 1980s, and evolved, through years, to the present number of different WebGIS, which have different territorial extensions: national (Italian National Cartographical Portal, http://www.pcn.minambiente.it; E-GEO Project, http://www.egeo.unisi.it), interregional (River Tiber Basin Authority, www.abtevere.it ), and regional (Veneto Region, www.regione.veneto.it). In this way we investigated most of the Italian WebGIS in order to verify their geographic range and the availability and quality of data useful for landslide hazard analyses. We noticed a large variability of the accessing information among the different browsers. In

  2. Relationship between geohydrology and Upper Pleistocene-Holocene evolution of the eastern region of the Province of Buenos Aires, Argentina

    Science.gov (United States)

    Capítulo, Leandro Rodrigues; Kruse, Eduardo E.

    2017-07-01

    The Upper Pleistocene-Holocene geological evolution, which is characterized by its landscape-forming energy and is related to geological and geomorphological complexity, has an impact on the groundwater dynamics of coastal aquifers. The geological configuration of a sector of the east coast of the Province of Buenos Aires was analyzed, as well as its connection with the geological and geomorphological history of the region during the Late Pleistocene and Holocene, and its influence on the regional and local geohydrological behaviour. This analysis was based on the application of the concept of hydrofacies. Boreholes were drilled and sampled (with depths of up to 40 m), and vertical electrical sounding, electrical tomography and pumping tests were undertaken. The description of the cutting samples by means of a stereo microscope, the interpretation of satellite images, and the construction of lithological and hydrogeological profiles and flow charts were carried out in the laboratory, and then integrated in a GIS. The identification of the lithological units and their distribution in the area allowed the construction of an evolutionary geological model for the Late Pleistocene and Holocene. Three aquifer units can be recognized: one of Late Pleistocene age (hydrofacies E) and the other two of Holocene age (hydrofacies A and C); their hydraulic connection depends on the occurrence and thickness variation of the aquitard units (hydrofacies B and D). The approach adopted allows the examination of the possibilities for groundwater exploitation and constitutes an applied conceptual framework to be taken into consideration when developing conceptual and numerical models at the local and regional scales.

  3. The use of a flood index to characterise flooding in the north-eastern region of Bangladesh

    Directory of Open Access Journals (Sweden)

    Bhattacharya B.

    2016-01-01

    Full Text Available Flooding in the Haor region in the north-east of Bangladesh is presented in this paper. A haor is a saucershaped depression, which is used during the dry period (Dec to mid-May for agriculture and as a fishery during the wet period (Jun-Nov. Pre-monsoon flooding till mid-May causes agricultural loss. The area is bordering India, and is fed by some flashy Indian catchments. The area is drained mainly by the Surma-Kushiyara river system. The terrain generally is flat and the flashy characteristics die out within a short distance from the border. Limited studies on the region, particularly with the help of numerical models, have been carried out in the past. Therefore, an objective of the current research was to set up numerical models capable of reasonably emulating the physical system. Such models could, for example, associate different gauges to the spatio-temporal variation of hydrodynamic variables and help in carrying out a systemic study on the flood propagation. A 1D2D model, with one-dimensional model for the rivers (based on MIKE 11 from DHI and a two-dimensional model for the haors (based on MIKE 21 from DHI were developed. In order to characterize flooding in the large area a flood index is proposed, which is computed based on the hydrograph characteristics such as the rising curve gradient, flood magnitude ratio and time to peak. The index was used in characterising flooding in the Haor region. In general, two groups of rivers were identified. The study enabled identifying the hot-spots in the study area with risks from flooding.

  4. Estimate of the size and demographic structure of the owned dog and cat population living in Veneto region (north-eastern Italy).

    Science.gov (United States)

    Capello, Katia; Bortolotti, Laura; Lanari, Manuela; Baioni, Elisa; Mutinelli, Franco; Vascellari, Marta

    2015-01-01

    The knowledge of the size and demographic structure of animal populations is a necessary prerequisite for any population-based epidemiological study, especially to ascertain and interpret prevalence data, to implement surveillance plans in controlling zoonotic diseases and, moreover, to provide accurate estimates of tumours incidence data obtained by population-based registries. The main purpose of this study was to provide an accurate estimate of the size and structure of the canine population in Veneto region (north-eastern Italy), using the Lincoln-Petersen version of the capture-recapture methodology. The Regional Canine Demographic Registry (BAC) and a sample survey of households of Veneto Region were the capture and recapture sources, respectively. The secondary purpose was to estimate the size and structure of the feline population in the same region, using the same survey applied for dog population. A sample of 2465 randomly selected households was drawn and submitted to a questionnaire using the CATI technique, in order to obtain information about the ownership of dogs and cats. If the dog was declared to be identified, owner's information was used to recapture the dog in the BAC. The study was conducted in Veneto Region during 2011, when the dog population recorded in the BAC was 605,537. Overall, 616 households declared to possess at least one dog (25%), with a total of 805 dogs and an average per household of 1.3. The capture-recapture analysis showed that 574 dogs (71.3%, 95% CI: 68.04-74.40%) had been recaptured in both sources, providing a dog population estimate of 849,229 (95% CI: 814,747-889,394), 40% higher than that registered in the BAC. Concerning cats, 455 of 2465 (18%, 95% CI: 17-20%) households declared to possess at least one cat at the time of the telephone interview, with a total of 816 cats. The mean number of cats per household was equal to 1.8, providing an estimate of the cat population in Veneto region equal to 663,433 (95% CI: 626

  5. Nemaha Uplift seismotectonic study: regional tectonics and seismicity of eastern Kansas. Technical progress report, October 1, 1978-September 30, 1979

    International Nuclear Information System (INIS)

    Wilson, F.W.

    1979-11-01

    Progress and results of all work on this project to the end of its second year, or September 30, 1978, were reported in NUREG/CR-0666, published March 1979. Project third-year activites and results include the following: continued operation of a regional microearthquake monitoring network which detected and located 26 regional events between October 1, 1978, and August 2, 1979; designing and building a triggering system to allow digitized recording of microearthquakes by a modified exploration seismography; continued surface and subsurface studies of selected areas along the Nemaha Uplift-Keweenanan Mafic belt trend; continued study of Precambrian rock types from recently drilled wells; beginning compilation of a fault catalog; terrain analysis and lineament studies which indicate that the alignment of stream drainages and divides are strongly controlled by basement and subsurface structure; continued reduction of gravity data for northeastern Kansas (a Bouguer gravity map probably will be available late Fall 1979); modification of the exploration seismograph system to a more efficient 12-channel Mini-Sosie system and completion of several line-miles of reflection profiling; and beginning integration of data from Oklahoma, Nebraska, and Iowa co-investigators. All major goals for FY 1979 were accomplished. 2 figures

  6. Oral disease-modifying therapies for multiple sclerosis in the Middle Eastern and North African (MENA) region: an overview.

    Science.gov (United States)

    Deleu, Dirk; Mesraoua, Boulenouar; Canibaño, Beatriz; Melikyan, Gayane; Al Hail, Hassan; El-Sheikh, Lubna; Ali, Musab; Al Hussein, Hassan; Ibrahim, Faiza; Hanssens, Yolande

    2018-06-18

    The introduction of new disease-modifying therapies (DMTs) for remitting-relapsing multiple sclerosis (RRMS) has considerably transformed the landscape of therapeutic opportunities for this chronic disabling disease. Unlike injectable drugs, oral DMTs promote patient satisfaction and increase therapeutic adherence. This article reviews the salient features about the mode of action, efficacy, safety, and tolerability profile of approved oral DMTs in RRMS, and reviews their place in clinical algorithms in the Middle East and North Africa (MENA) region. A systematic review was conducted using a comprehensive search of MEDLINE, PubMed, Cochrane Database of Systematic Reviews (period January 1, 1995-January 31, 2018). Additional searches of the American Academy of Neurology and European Committee for Treatment and Research in Multiple Sclerosis abstracts from 2012-2017 were performed, in addition to searches of the Food and Drug Administration and European Medicines Agency websites, to obtain relevant safety information on these DMTs. Four oral DMTs: fingolimod, teriflunomide, dimethyl fumarate, and cladribine have been approved by the regulatory agencies. Based on the number needed to treat (NNT), the potential role of these DMTs in the management of active and highly active or rapidly evolving RRMS is assessed. Finally, the place of the oral DMTs in clinical algorithms in the MENA region is reviewed.

  7. Landslide and flood hazard assessment in urban areas of Levoča region (Eastern Slovakia)

    Science.gov (United States)

    Magulova, Barbora; Caporali, Enrica; Bednarik, Martin

    2010-05-01

    The case study presents the use of statistical methods and analysis tools, for hazard assessment of "urbanization units", implemented in a Geographic Information Systems (GIS) environment. As a case study, the Levoča region (Slovakia) is selected. The region, with a total area of about 351 km2, is widely affected by landslides and floods. The problem, for small urbanization areas, is nowadays particularly significant from the socio-economic point of view. It is considered, presently, also an increasing problem, mainly because of climate change and more frequent extreme rainfall events. The geo-hazards are evaluated using a multivariate analysis. The landslide hazard assessment is based on the comparison and subsequent statistical elaboration of territorial dependence among different input factors influencing the instability of the slopes. Particularly, five factors influencing slope stability are evaluated, i.e. lithology, slope aspect, slope angle, hypsographic level and present land use. As a result a new landslide susceptibility map is compiled and different zones of stable, dormant and non-stable areas are defined. For flood hazard map a detailed digital elevation model is created. A compose index of flood hazard is derived from topography, land cover and pedology related data. To estimate flood discharge, time series of stream flow and precipitation measurements are used. The assessment results are prognostic maps of landslide hazard and flood hazard, which presents the optimal base for urbanization planning.

  8. Oxidative Unfolding of the Rubredoxin Domain and the Natively Disordered N-terminal Region Regulate the Catalytic Activity of Mycobacterium tuberculosis Protein Kinase G.

    Science.gov (United States)

    Wittwer, Matthias; Luo, Qi; Kaila, Ville R I; Dames, Sonja A

    2016-12-30

    Mycobacterium tuberculosis escapes killing in human macrophages by secreting protein kinase G (PknG). PknG intercepts host signaling to prevent fusion of the phagosome engulfing the mycobacteria with the lysosome and, thus, their degradation. The N-terminal NORS (no regulatory secondary structure) region of PknG (approximately residues 1-75) has been shown to play a role in PknG regulation by (auto)phosphorylation, whereas the following rubredoxin-like metal-binding motif (RD, residues ∼74-147) has been shown to interact tightly with the subsequent catalytic domain (approximately residues 148-420) to mediate its redox regulation. Deletions or mutations in NORS or the redox-sensitive RD significantly decrease PknG survival function. Based on combined NMR spectroscopy, in vitro kinase assay, and molecular dynamics simulation data, we provide novel insights into the regulatory roles of the N-terminal regions. The NORS region is indeed natively disordered and rather dynamic. Consistent with most earlier data, autophosphorylation occurs in our assays only when the NORS region is present and, thus, in the NORS region. Phosphorylation of it results only in local conformational changes and does not induce interactions with the subsequent RD. Although the reduced, metal-bound RD makes tight interactions with the following catalytic domain in the published crystal structures, it can also fold in its absence. Our data further suggest that oxidation-induced unfolding of the RD regulates substrate access to the catalytic domain and, thereby, PknG function under different redox conditions, e.g. when exposed to increased levels of reactive oxidative species in host macrophages. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

  9. Viral etiology, seasonality and severity of hospitalized patients with severe acute respiratory infections in the Eastern Mediterranean Region, 2007-2014.

    Science.gov (United States)

    Horton, Katherine C; Dueger, Erica L; Kandeel, Amr; Abdallat, Mohamed; El-Kholy, Amani; Al-Awaidy, Salah; Kohlani, Abdul Hakim; Amer, Hanaa; El-Khal, Abel Latif; Said, Mayar; House, Brent; Pimentel, Guillermo; Talaat, Maha

    2017-01-01

    Little is known about the role of viral respiratory pathogens in the etiology, seasonality or severity of severe acute respiratory infections (SARI) in the Eastern Mediterranean Region. Sentinel surveillance for SARI was conducted from December 2007 through February 2014 at 20 hospitals in Egypt, Jordan, Oman, Qatar and Yemen. Nasopharyngeal and oropharyngeal swabs were collected from hospitalized patients meeting SARI case definitions and were analyzed for infection with influenza, respiratory syncytial virus (RSV), adenovirus (AdV), human metapneumovirus (hMPV) and human parainfluenza virus types 1-3 (hPIV1-3). We analyzed surveillance data to calculate positivity rates for viral respiratory pathogens, describe the seasonality of those pathogens and determine which pathogens were responsible for more severe outcomes requiring ventilation and/or intensive care and/or resulting in death. At least one viral respiratory pathogen was detected in 8,753/28,508 (30.7%) samples tested for at least one pathogen and 3,497/9,315 (37.5%) of samples tested for all pathogens-influenza in 3,345/28,438 (11.8%), RSV in 3,942/24,503 (16.1%), AdV in 923/9,402 (9.8%), hMPV in 617/9,384 (6.6%), hPIV1 in 159/9,402 (1.7%), hPIV2 in 85/9,402 (0.9%) and hPIV3 in 365/9,402 (3.9%). Multiple pathogens were identified in 501/9,316 (5.4%) participants tested for all pathogens. Monthly variation, indicating seasonal differences in levels of infection, was observed for all pathogens. Participants with hMPV infections and participants less than five years of age were significantly less likely than participants not infected with hMPV and those older than five years of age, respectively, to experience a severe outcome, while participants with a pre-existing chronic disease were at increased risk of a severe outcome, compared to those with no reported pre-existing chronic disease. Viral respiratory pathogens are common among SARI patients in the Eastern Mediterranean Region. Ongoing surveillance is

  10. Preliminary Interpretations of Multi-Channel Seismic Reflection and Magnetic Data on North Anatolian Fault (NAF) in the Eastern Marmara Region, Turkey

    Science.gov (United States)

    Gözde Okut Toksoy, Nigar; Kurt, Hülya; İşseven, Turgay

    2017-04-01

    The North Anatolian Fault (NAF) is 1600 km long, right lateral strike-slip fault nearly E-W elongated between Karlıova in the east and Saros Gulf in the west. NAF splays into two major strands near the west of Bolu city as Northern and Southern strands. Northern strand passes Sapanca Lake and extends towards west and reaches Marmara Sea through the Gulf of Izmit. The area has high seismicity; 1999 Kocaeli (Mw=7.4) and 1999 Düzce (Mw=7.2) earthquakes caused approximately 150 km long surface rupture between the Gulf of Izmit and Bolu. The rupture has four distinct fault segments as Gölcük, Sapanca, Sakarya, and Karadere from west to east. In this study multi-channel seismic and magnetic data are collected for the first time on the Sapanca Segment to investigate the surficial and deeper geometry of the NAF. Previously, the NAF in the eastern Marmara region is investigated using by paleo-seismological data from trenches on the surface rupture of fault or the geomorphological data (Lettis et al., 2000; Dikbaş and Akyüz, 2010) which have shallower depth targets. Crustal structure and seismic velocities for Central Anatolia and eastern Marmara regions are obtained from deeper targeted refraction data (Gürbüz et al., 1992). However, their velocity models do not have the spatial resolution to determine details of the fault zone structure. Multi-channel seismic and magnetic data in this study were acquired on two N-S directed profiles crossing NAF perpendicularly near Kartepe on the western part of the Sapanca Lake in October 2016. The receiver interval is 5 m, shot interval is 5-10 m, and the total length of the profiles are approximately 1400 m. Buffalo Gun is used as a seismic source for deeper penetration. Conventional seismic reflection processing steps are applied to the data. These are geometry definition, editing, filtering, static correction, velocity analysis and deconvolution, stacking and migration. Echos seismic software package in Geophysical Department

  11. Radiographic evaluation of third-molar development in relation to the chronological age of Turkish children in the southwest Eastern Anatolia region.

    Science.gov (United States)

    Karataş, Orhan H; Öztürk, Fırat; Dedeoğlu, Numan; Çolak, Cemil; Altun, Oğuzhan

    2013-10-10

    To study the chronological age of third-molar mineralisation of Turkish children from the southwest Eastern Anatolia region, the Demirjian staging method was used to determine the stage of the mineralisation of four third molars (18, 28, 38 and 48) and to compare third-molar development by sex and age with the results of previous studies. The study comprised 832 Turkish children from the southwest Eastern Anatolia region aged 6-16 years based on radiological evidence from digital orthopantomograms. The mean age of the 832 patients was 11.03±1.98 years, with 424 males (mean age, 10.97±1.97) and 408 females (mean age, 11.09±2.00). The orthopantomograms were scored by two observers. The Wilcoxon matched-pairs signed-rank test used to assess intra- and inter-observer assessment revealed strong agreement between both observers' measurements. Statistical analysis of the association between sex and age was performed with the Mann-Whitney U-test and the Wilcoxon test. Regression analysis was performed to obtain regression formulae for calculating the dental and the chronological age. The statistical analysis showed a strong correlation between age and third-molar development in males (R(2)=0.61) and females (R(2)=0.63). New equations (age=7.49+0.69, development stage (DS) 38+0.70, DS18) were derived for estimation of the chronological age. The results showed that there was no significant difference in mineralisation between 18 and 28 and 38 and 48 in males or females. For both sexes, the dental age was lower than the chronological age. Males reached the developmental stages earlier than females. In the whole population, the boys' and the girls' dental ages were 0.84 years and 0.16 years earlier, respectively, than their chronological ages. The use of third-molar teeth as a developmental marker is suitable, particularly when comparing the obtained standard deviation with other skeletal-age calculation techniques. Copyright © 2013 Elsevier Ireland Ltd. All rights

  12. Biostratigraphic correlation of the western and eastern margins of the Labrador-Baffin Seaway and implications for the regional geology

    Directory of Open Access Journals (Sweden)

    Henrik Nøhr-Hansen

    2016-12-01

    Full Text Available New analyses of the palynological assemblages in 13 offshore wells on the Canadian margin and six on the West Greenland Margin, in conjunction with onshore data, have led to a new biostratigraphic framework for the Cretaceous–Cenozoic strata of the Labrador Sea – Davis Strait – Baffin Bay (Labrador–Baffin Seaway region and the first broad biostratigraphic correlation of the Canadian and Greenland margins. This framework is based on 167 last occurrences and 18 local/regional peak/common-occurrence events for dinocysts, miospores, fungal spores and Azolla. Detailed biostratigraphic evidence has confirmed the following hiatuses: pre-Aptian in the Hopedale Basin; pre-Albian in the Saglek Basin; Albian–Turonian in some wells of the Hopedale Basin; Turonian–Santonian/Campanian in some areas; pre-Campanian and late Campanian – Thanetian on the Greenland Margin; late Maastrichtian and Danian in some wells of the Hopedale Basin and in the Saglek Basin; Selandian in part of the Hopedale Basin, in all the Saglek Basin wells and in two wells on the West Greenland Margin; late Ypresian and/or Lutetian on both sides; Oligocene to middle Miocene of considerable variability on both margins, with all of the Oligocene and the lower Miocene missing in all the West Greenland Margin wells; and middle to late Miocene on the western side. On the Canadian margin, the hiatuses can be partially matched with the five previously recognised regional unconformities; on the Greenland margin, however, the relationship to the five unconformities is more tenuous. Palynomorph assemblages show that most Aptian to Albian sediments were deposited in generally non-marine to marginal marine settings, interrupted by a short-lived shallow marine episode in the Aptian. A marine transgression started in the Cenomanian–Turonian and led to the most open-marine, oceanic conditions in the Campanian–Lutetian; shallowing probably started in the late Lutetian and continued into

  13. Geophysical Data (Gravity and Magnetic) from the Area Between Adana, Kahramanmaras and Hatay in the Eastern Mediterranean Region: Tectonic Implications

    Science.gov (United States)

    Over, Semir; Akin, Ugur; Sen, Rahime

    2018-01-01

    The gravity and magnetic maps of the area between Adana-Kahramanmaras-Hatay provinces were produced from a compilation of data gathered during the period between 1973 and 1989. Reduced to the pole (RTP) and pseudo-gravity transformation (PGT) methods were applied to the magnetic data, while derivative ratio (DR) processing was applied to both gravity and magnetic data, respectively. Bouguer, RTP and PGT maps show the image of a buried structure corresponding to ophiolites under undifferentiated Quaternary deposits in the Adana depression and Iskenderun Gulf. DR maps show two important faults which reflect the tectonic framework in the study area: (1) the Karatas-Osmaniye Fault extending from Osmaniye to Karatas in the south between Adana and Iskenderun depressions and (2) Amanos Fault (southern part of East Anatolian Fault) in the Hatay region running southward from Turkoglu to Amik Basin along Amanos Mountain forming the actual plate boundary between the Anatolian block (part of Eurasian plate) and Arabian plate.

  14. Hydrogeological modelling of the eastern region of Areco river locally detailed on Atucha I and II nuclear power plants area

    International Nuclear Information System (INIS)

    Grattone, Natalia I.; Fuentes, Nestor O.

    2009-01-01

    Water flow behaviour of Pampeano aquifer was modeled using Visual Mod-flow software Package 2.8.1 with the assumption of a free aquifer, within the region of the Areco river and extending to the rivers of 'Canada Honda' and 'de la Cruz'. Steady state regime was simulated and grid refinement allows obtaining locally detailed calculation in the area of Atucha I and II Nuclear power plants, in order to compute unsteady situations as the consequence of water flow variations from and to the aquifer, enabling the model to study the movement of possible contaminant particles in the hydrogeologic system. In this work the effects of rivers action, the recharge conditions and the flow lines are analyzed, taking always into account the range of reliability of obtained results, considering the incidence of uncertainties introduced by data input system, the estimates and interpolation of parameters used. (author)

  15. Selected ground-water data for Yucca Mountain Region, southern Nevada and eastern California, through December 22

    International Nuclear Information System (INIS)

    La Camera, R.J.; Westenburg, C.L.

    1994-01-01

    The U.S. Geological Survey, in support of the U.S. Department of Energy, Yucca Mountain Site-Characterization Project, collects, compiles, and summarizes hydrologic data in the Yucca Mountain region. The data are collected to allow assessments of ground-water resources during studies to determine the potential suitability of Yucca Mountain for storing high-level nuclear waste. Data on ground-water levels at 36 sites, ground-water discharge at 6 sites, ground-water quality at 19 sites, and ground-water withdrawals within Crater Flat, Jackass Flats, Mercury Valley, and the Amargosa Desert are presented. Data on ground-water levels, discharges, and withdrawals collected by other agencies (or as part of other programs) are included to further indicate variations through time at selected monitoring locations. Data are included in this report from 1910 through 1992

  16. Eastern Europe

    International Nuclear Information System (INIS)

    Baret, J.P.; Corcuff, A.; Jousten, M.; Cherie, J.B.; Gorge, X.; Augustin, X.; Belime, F.

    1999-01-01

    By its economical and political impact, nuclear energy has an important contribution the countries of Eastern Europe that goes beyond simple energy source. The most important challenge is to gain a safety culture. Improvements have been noted but the reactors safety must stay a priority of the international cooperation in Eastern Europe. The plan for the completion and improvement of Mochovce nuclear plant is described, the situation of Chernobyl and how to make the sarcophagus in safe is discussed, the experience of a french P.M.E. ( small and medium size firm) called Corys Tess that has chosen to position itself on the Eastern Europe nuclear market is related. (N.C.)

  17. Mapping of immunogenic and protein-interacting regions at the surface of the seven-bladed β-propeller domain of the HIV-1 cellular interactor EED

    Directory of Open Access Journals (Sweden)

    Gouet Patrice

    2008-02-01

    Full Text Available Abstract Background The human EED protein, a member of the superfamily of Polycomb group proteins, is involved in multiple cellular protein complexes. Its C-terminal domain, which is common to the four EED isoforms, contains seven repeats of a canonical WD-40 motif. EED is an interactor of three HIV-1 proteins, matrix (MA, integrase (IN and Nef. An antiviral activity has been found to be associated with isoforms EED3 and EED4 at the late stage of HIV-1 replication, due to a negative effect on virus assembly and genomic RNA packaging. The aim of the present study was to determine the regions of the EED C-terminal core domain which were accessible and available to protein interactions, using three-dimensional (3D protein homology modelling with a WD-40 protein of known structure, and epitope mapping of anti-EED antibodies. Results Our data suggested that the C-terminal domain of EED was folded as a seven-bladed β-propeller protein. During the completion of our work, crystallographic data of EED became available from co-crystals of the EED C-terminal core with the N-terminal domain of its cellular partner EZH2. Our 3D-model was in good congruence with the refined structural model determined from crystallographic data, except for a unique α-helix in the fourth β-blade. More importantly, the position of flexible loops and accessible β-strands on the β-propeller was consistent with our mapping of immunogenic epitopes and sites of interaction with HIV-1 MA and IN. Certain immunoreactive regions were found to overlap with the EZH2, MA and IN binding sites, confirming their accessibility and reactivity at the surface of EED. Crystal structure of EED showed that the two discrete regions of interaction with MA and IN did not overlap with each other, nor with the EZH2 binding pocket, but were contiguous, and formed a continuous binding groove running along the lateral face of the β-propeller. Conclusion Identification of antibody-, MA-, IN- and EZH2

  18. Estimation of monthly global solar radiation in the eastern Mediterranean region in Turkey by using artificial neural networks

    International Nuclear Information System (INIS)

    Sahan, Muhittin; Yakut, Emre

    2016-01-01

    In this study, an artificial neural network (ANN) model was used to estimate monthly average global solar radiation on a horizontal surface for selected 5 locations in Mediterranean region for period of 18 years (1993-2010). Meteorological and geographical data were taken from Turkish State Meteorological Service. The ANN architecture designed is a feed-forward back-propagation model with one-hidden layer containing 21 neurons with hyperbolic tangent sigmoid as the transfer function and one output layer utilized a linear transfer function (purelin). The training algorithm used in ANN model was the Levenberg Marquand back propagation algorith (trainlm). Results obtained from ANN model were compared with measured meteorological values by using statistical methods. A correlation coefficient of 97.97 (~98%) was obtained with root mean square error (RMSE) of 0.852 MJ/m 2 , mean square error (MSE) of 0.725 MJ/m 2 , mean absolute bias error (MABE) 10.659MJ/m 2 , and mean absolute percentage error (MAPE) of 4.8%. Results show good agreement between the estimated and measured values of global solar radiation. We suggest that the developed ANN model can be used to predict solar radiation another location and conditions

  19. Studies on the distribution, sale, handling and usage of agrochemicals in Ashanti, Brong Ahafo and Eastern regions of Ghana

    International Nuclear Information System (INIS)

    Osafo-Acquaah, S.; Frimpong, E.

    1997-01-01

    Studies were carried on the distribution, sale, handling and usage and agrochemicals in 19 major towns located in three regions noted for their intensive agricultural activities and covering 500,000 hectares of land area in Ghana. The most prevalent of the agrochemicals were insecticides (52%) followed by herbicides (28%) and fungicides (16%). Of these the organophosphates constituted 24% and the organochlorines 6% in terms of the total numbers of pesticides sold, though lindane and endosulfan were among the insecticides most frequently used by farmers. The fungicide, copper oxychloride as ''Kocide'', and the insecticide, λ cyhalothrin as ''Karate'', with 39% and 22% respectively of the sales by volume, were found to be the most widely used agrochemicals. Most of the merchants of agrochemicals and the farmers had only primary school education and had very little knowledge on the handling and safety aspects of the use of agrochemicals. The Extension Service to the farmers was inadequate and the farmers depended largely on the agrochemicals merchants for information on pesticide usage. (author). 9 tabs

  20. The heparin-binding site in tetranectin is located in the N-terminal region and binding does not involve the carbohydrate recognition domain.

    Science.gov (United States)

    Lorentsen, R H; Graversen, J H; Caterer, N R; Thogersen, H C; Etzerodt, M

    2000-04-01

    Tetranectin is a homotrimeric plasma and extracellular-matrix protein that binds plasminogen and complex sulphated polysaccharides including heparin. In terms of primary and tertiary structure, tetranectin is related to the collectin family of Ca(2+)-binding C-type lectins. Tetranectin is encoded in three exons. Exon 3 encodes the carbohydrate recognition domain, which binds to kringle 4 in plasminogen at low levels of Ca(2+). Exon 2 encodes an alpha-helix, which is necessary and sufficient to govern the trimerization of tetranectin by assembling into a triple-helical coiled-coil structural element. Here we show that the heparin-binding site in tetranectin resides not in the carbohydrate recognition domain but within the N-terminal region, comprising the 16 amino acid residues encoded by exon 1. In particular, the lysine residues in the decapeptide segment KPKKIVNAKK (tetranectin residues 6-15) are shown to be of primary importance in heparin binding.

  1. Accuracy of serum markers, progesterone and vitamins measurements for early screening of abortions in the eastern region of Algeria (Batna

    Directory of Open Access Journals (Sweden)

    Sara Mouffouk

    2018-02-01

    Full Text Available Spontaneous abortion is an involuntary interruption of pregnancy before 22 weeks of gestation. According to the Algerian National Institute of Public Health the percentage of women suffering from permanent complications during pregnancy is approximately 15%. The aim of this study is the determination of some biochemical analytes, including folic acid, vitamin B12, alphafoetoproteine, beta human chorionic gonadotropin (β-hCG, progesterone and oestradiol (uE3, which are involved in the detection of pregnancy failures. This case-control study was carried out on women in the process of abortion and a control group with viable pregnancies in the East region of Algeria (Batna during the year 2015. In the present investigation, 69 pregnant women during the first and second trimester were recruited during the first and second trimesters as cases (with miscarriages and the control group (n=69 was constituted of women who had normal ultrasound. The average concentration of alpha-fetoprotein is significantly low during the first trimester, but it is very high during the second trimester between cases and controls. The median values of β- hCG, uE3 and progesterone decrease very significantly. The mean concentration of serum folate and vitamin B12 did not change significantly between cases and controls in the first and second trimesters. The results of this study revealed that, spontaneous abortions are associated with changes in serum markers and progesterone, which could form an important part in the early diagnosis of non-viable pregnancies. However, vitamins levels have no significant effects on these pregnancies.

  2. Regional Land Subsidence Analysis in Eastern Beijing Plain by InSAR Time Series and Wavelet Transforms

    Directory of Open Access Journals (Sweden)

    Mingliang Gao

    2018-02-01

    Full Text Available Land subsidence is the disaster phenomenon of environmental geology with regionally surface altitude lowering caused by the natural or man-made factors. Beijing, the capital city of China, has suffered from land subsidence since the 1950s, and extreme groundwater extraction has led to subsidence rates of more than 100 mm/year. In this study, we employ two SAR datasets acquired by Envisat and TerraSAR-X satellites to investigate the surface deformation in Beijing Plain from 2003 to 2013 based on the multi-temporal InSAR technique. Furthermore, we also use observation wells to provide in situ hydraulic head levels to perform the evolution of land subsidence and spatial-temporal changes of groundwater level. Then, we analyze the accumulated displacement and hydraulic head level time series using continuous wavelet transform to separate periodic signal components. Finally, cross wavelet transform (XWT and wavelet transform coherence (WTC are implemented to analyze the relationship between the accumulated displacement and hydraulic head level time series. The results show that the subsidence centers in the northern Beijing Plain is spatially consistent with the groundwater drop funnels. According to the analysis of well based results located in different areas, the long-term groundwater exploitation in the northern subsidence area has led to the continuous decline of the water level, resulting in the inelastic and permanent compaction, while for the monitoring wells located outside the subsidence area, the subsidence time series show obvious elastic deformation characteristics (seasonal characteristics as the groundwater level changes. Moreover, according to the wavelet transformation, the land subsidence time series at monitoring well site lags several months behind the groundwater level change.

  3. The 89 Ma Tortugal komatiitic suite, Costa Rica: Implications for a common geological origin of the Caribbean and Eastern Pacific region from a mantle plume

    Science.gov (United States)

    Alvarado, Guillermo E.; Denyer, Percy; Sinton, Christopher W.

    1997-05-01

    Komatiites are reported for the first time in the northern part of the Gulf of Nicoya, Costa Rica. These rocks, dated at 89.7 ± 1.4 Ma (Turonian) by 40Ar/39Ar methods, occur as a large, elongated (14 km long, 1.5 km wide) N60°W striking body in the ophiolitic Nicoya Complex. These lavas have high MgO (26% 29%), Ni, and Cr, have high CaO/Al2O3 (0.98 1.08) and moderate Al2O3/TiO2 (5.55 8.44) ratios, and are depleted in Al2O3 (4% 5.5%), K2O (0.02% 0.37%), and TiO2 (0.59% 0.9%). Although these lavas are cumulates, their geochemical composition indicates an origin from a primary komatiitic magma, with a melting temperature of 1700 °C at a depth of 150 km. Similarities in the petrology and age (88 90 Ma) of Gorgona, Curaìao, and Nicoya-Tortugal mafic and ultramafic volcanic rocks suggest that these rocks had a common origin. These occurrences suggest a single hotspot center over a large area of the Caribbean and Eastern Pacific Mesozoic region due to a major thermal anomaly in the mantle, such as a hot, rising, convective plume.

  4. Identification, Quantification, and Toxicity of PCDDs and PCDFs in Soils from Industrial Areas in the Central and Eastern Regions of Saudi Arabia.

    Science.gov (United States)

    Al-Wabel, Mohammad I; El-Saeid, Mohamed H; Usman, Adel R A; Al-Turki, Ali M; Ahmad, Mahtab; Hassanin, Ashraf S; El-Naggar, Ahmed H; Alenazi, Khaled K H

    2016-05-01

    This study was conducted to identify and quantify polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) in soil samples collected from selected industrial areas in the central and eastern regions of Saudi Arabia. All the investigated compounds of PCDDs/PCDFs were identified in the studied locations. The average concentrations of PCDDs (sum of seven congeners measured) ranged from 11.5 to 59.6 pg g(-1), with a maximum concentration of 125.7 pg g(-1) at an oil refinery station followed by 100.9 pg g(-1) at a cement factory. The average concentrations of PCDFs (sum of 10 congeners measured) accounted for 11.68-19.35 pg g(-1), with a maximum concentration of 38.67 pg g(-1) at the cement factory. It was generally observed that the soil samples collected from industrial areas have substantially high toxicity equivalence (TEQ) values of PCDDs/PCDFs compared to soils of remote areas. Principal component analysis revealed that the cement factories and oil refineries were the primary sources of PCDDs and PCDFs.

  5. Cost/benefit analysis of biomass energy supply options for rural smallholders in the semi-arid eastern part of Shinyanga Region in Tanzania

    Energy Technology Data Exchange (ETDEWEB)

    Wiskerke, W.T.; Dornburg, V.; Faaij, A.P.C. [Department of Science, Technology and Society, Utrecht University, Heidelberglaan 2, 3584 CS, Utrecht (Netherlands); Rubanza, C.D.K. [Tanzania Forestry Research Institute (TAFORI)/National Forest Resource Management and Agroforestry Centre (NACRAF), P.O. Box 1257, Shinyanga (Tanzania); Malimbwi, R.E. [Faculty of Forestry and Natural Resources, Sokoine University, P.O. Box 3010, Morogoro (Tanzania)

    2010-01-15

    This study analyzes the economic feasibility of sustainable smallholder bio-energy production under semi-arid conditions. The eastern part of Shinyanga region in Tanzania was chosen as a case study area. Three different sustainable biomass energy supply systems were compared by means of cost/benefit analysis: a small-scale forestation project for carbon sequestration, a short rotation woodlot and a Jatropha plantation, thereby using the produced Jatropha oil as a substitute for fuelwood or diesel. Rotational woodlots are most profitable with a Net Present Value of up to US${sub 2007} 1165/ha, a return on labour of up to US${sub 2007} 6.69/man-day and a fuelwood production cost of US${sub 2007} 0.53/GJ, compared to a local market price of US${sub 2007} 1.95/GJ. With a production cost of US${sub 2007} 19.60/GJ, Jatropha oil is too expensive to be used as an alternative for fuelwood. Instead it can be utilized economically as a diesel substitute, at an observed diesel cost of US${sub 2007} 1.49/l. The mean annual biomass increment (MAI) in semi-arid East Shinyanga is too low to collect sufficient benefits from trading forestation carbon credits under the Clean Development Mechanism (CDM) to cover the costs of forestation and forest management. (author)

  6. Tiny Turtles Purchased at Pet Stores are a Potential High Risk for Salmonella Human Infection in the Valencian Region, Eastern Spain.

    Science.gov (United States)

    Marin, Clara; Vega, Santiago; Marco-Jiménez, Francisco

    2016-07-01

    Turtles may be considered unsafe pets, particularly in households with children. This study aimed to assess Salmonella carriage by turtles in pet stores and in private ownership to inform the public of the potential health risk, enabling informed choices around pet selection. During the period between September and October 2013, 24 pet stores and 96 private owners were sampled in the Valencian Region (Eastern Spain). Salmonella identification procedure was based on ISO 6579: 2002 recommendations (Annex D). Salmonella strains were serotyped in accordance with Kauffman-White-Le-Minor technique. The rate of isolation of Salmonella was very high from pet store samples (75.0% ± 8.8%) and moderate for private owners (29.0% ± 4.6%). Serotyping revealed 18 different serotypes among two Salmonella enterica subspecies: S. enterica subsp. enterica and S. enterica subsp. diarizonae. Most frequently isolated serotypes were Salmonella Typhimurium (39.5%, 17/43) and Salmonella Pomona (9.3%, 4/43). Serotypes identified have previously been reported in turtles, and child Salmonella infections associate with pet turtle exposure. The present study clearly demonstrates that turtles in pet stores, as well as in private owners, could be a direct or indirect source of a high risk of human Salmonella infections. In addition, pet stores should advise their customers of the potential risks associated with reptile ownership.

  7. Results of the Global Youth Tobacco Survey and implementation of the WHO Framework Convention on Tobacco Control in the WHO Eastern Mediterranean Region (EMR) countries.

    Science.gov (United States)

    Usmanova, Gulnoza; Mokdad, Ali H

    2013-12-01

    We used Global Youth Tobacco Survey (GYTS) data collected over time to monitor articles of the World Health Organization Framework Convention on Tobacco Control (WHO FCTC) in WHO Eastern Mediterranean Region (EMR). The GYTS is a school-based survey, conducted in 23 countries in WHO EMR countries from 1999-2008. The prevalence of current smokeless tobacco use was high compared to cigarette use in all countries. In general, the following changes were observed between baseline and repeated surveys: in five countries fewer youth supported a ban on smoking in public places. In four countries more youth saw actors smoking on TV and were exposed to second-hand smoke (SHS) outside of home. Fewer youth were offered free cigarettes in ten countries; in eight countries youth saw less advertisement on TV; in seven countries youth had fewer items with a tobacco logo, discussed more reasons for smoking and dangers of smoking, and were less exposed to SHS at home; in six countries youth saw less advertisement at sports events. The GYTS data can be used for monitoring, evaluation of national tobacco control plans and defining future directions for tobacco control. Copyright © 2013 Ministry of Health, Saudi Arabia. Published by Elsevier Ltd. All rights reserved.

  8. The burden of mental disorders in the Eastern Mediterranean region, 1990-2015: findings from the global burden of disease 2015 study.

    Science.gov (United States)

    2017-08-03

    Mental disorders are among the leading causes of nonfatal burden of disease globally. We used the global burden of diseases, injuries, and risk factors study 2015 to examine the burden of mental disorders in the Eastern Mediterranean region (EMR). We defined mental disorders according to criteria proposed in the diagnostic and statistical manual of mental disorders IV and the 10th International Classification of Diseases. Mental disorders contributed to 4.7% (95% uncertainty interval (UI) 3.7-5.6%) of total disability-adjusted life-years (DALYs), ranking as the ninth leading cause of disease burden. Depressive disorders and anxiety disorders were the third and ninth leading causes of nonfatal burden, respectively. Almost all countries in the EMR had higher age-standardized mental disorder DALYs rates compared to the global level, and in half of the EMR countries, observed mental disorder rates exceeded the expected values. The burden of mental disorders in the EMR is higher than global levels, particularly for women. To properly address this burden, EMR governments should implement nationwide quality epidemiological surveillance of mental disorders and provide adequate prevention and treatment services.

  9. Calcium-Dependent Energetics of Calmodulin Domain Interactions with Regulatory Regions of the Ryanodine Receptor Type 1 (RyR1)

    Science.gov (United States)

    Newman, Rhonda A.; Sorensen, Brenda R.; Kilpatrick, Adina M.; Shea, Madeline A.

    2014-01-01

    Calmodulin (CaM) plays a vital role in calcium homeostasis by allosterically modulating intracellular calcium channels including the homo-tetrameric human Ryanodine Receptor Type 1 (hRyR1). Apo (calcium-free) CaM activates hRyR1 while calcium-saturated CaM inhibits it. Two CaM-binding regions (residues 1975–1999 and 3614–3643) identified in each RyR1 monomer were proposed to allow CaM to bridge adjacent RyR1 subunits. We explored the distinct roles of CaM domains by using fluorescence anisotropy to determine the affinity of CaM1–148 (full-length), CaM1–80 (N-domain) and CaM76–148 (C-domain) for peptides encompassing hRyR1 residues 1975–1999 or 3614–3643. Both CaM1–148 and CaM76–148 associated in a calcium-independent manner with similar affinities for hRyR1(3614–3643)p while CaM1–80 required calcium and bound ~250-fold more weakly. Association of CaM1–148, CaM1–80 and CaM76–148 with hRyR1(1975–1999)p was much less favorable than with hRyR1(3614–3643)p; differences between the two CaM domains were smaller. Equilibrium calcium titrations monitored by steady-state fluorescence demonstrated that both hRyR1 peptides increased the calcium-binding affinity of both CaM domains. These thermodynamic properties support a prior model in which the CaM C-domain associates with RyR1(3614–3643) at low levels of calcium, positioning CaM to rapidly respond to calcium efflux. However, the affinity of the N-domain of CaM for hRyR1(1975–1999)p is insufficient to explain a model in which CaM bridges adjacent RyR1 subunits within the tetramer. This indicates that other protein factors or properties of the tertiary or quaternary structure of hRyR1 contribute to the energetics of CaM-mediated regulation. PMID:25145833