Alteration of the rat cecal microbiome during colonization with the helminth Hymenolepis diminuta.

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McKenney, Erin A; Williamson, Lauren; Yoder, Anne D; Rawls, John F; Bilbo, Staci D; Parker, William

2015-01-01

The microbiome is now widely recognized as being important in health and disease, and makes up a substantial subset of the biome within the ecosystem of the vertebrate body. At the same time, multicellular, eukaryotic organisms such as helminths are being recognized as an important component of the biome that shaped the evolution of our genes. The absence of these macroscopic organisms during the early development and life of humans in Western culture probably leads to a wide range of human immunological diseases. However, the interaction between the microbiome and macroscopic components of the biome remains poorly characterized. In this study, the microbiome of the cecum in rats colonized for 2 generations with the small intestinal helminth Hymenolepis diminuta was evaluated. The introduction of this benign helminth, which is of considerable therapeutic interest, led to several changes in the cecal microbiome. Most of the changes were within the Firmicutes phylum, involved about 20% of the total bacteria, and generally entailed a shift from Bacilli to Clostridia species in the presence of the helminth. The results point toward ecological relationships between various components of the biome, with the observed shifts in the microbiome suggesting potential mechanisms by which this helminth might exert therapeutic effects.

Evaluación experimental de Ulomoides dermestoides (Tenebrionidae como hospedero intermediario de Hymenolepis diminuta

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Diana Villegas-Fudino

Full Text Available El objetivo del estudio fue determinar si Ulomoides dermestoides se comporta como hospedero intermediario de Hymenolepis diminuta, por lo que cien de ellos se infectaron experimentalmente con huevos del cestodo. Como resultado se obtuvo que en el 92% de los insectos se formaron cisticercoides que, inoculados en ratas de laboratorio, desarrollaron el estadio adulto con cuyos huevos se repitieron nuevas infecciones obteniendo los mismos resultados, por lo que se puede señalar que U. dermestoides experimentalmente se comporta como hospedero intermediario

Application of Glomus sp. and Pseudomonas diminuta Reduce the Use of Chemical Fertilizers in Production of Potato Grown on Different Soil Types

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Nurbaity, A.; Sofyan, E. T.; Hamdani, J. S.

2016-08-01

The use of high chemical fertilizer rates in potato production has been applied on the farm in Indonesia. Application of biofertilizer consists of arbuscular mycorrhizal fungi has been tested to reduce the use of NPK rates in production of potato and to determine whether different soil types will have different response to this biofertilizer. A greenhouse experiment was conducted using mixtures of spores of Glomus sp. and inoculant of mycorrhizal helper bacteria Pseudomonas diminuta, applied at different rates of NPK fertilizer (0, 25, 50, 75 and 100% of recommended rates) and different soil types (Andisols and Inceptisols). Results of experiment showed that application of Glomus sp. and P. diminuta reduced the use of NPK up to 50%, where the growth (plant height and tuber number), N,P,K uptake and tuber yields of potato had similar effect to the highest recommendation rate of NPK fertilizer. Inceptisols in general had better response to the biofertiliser compared to Andisols. Findings from this experiment confirmed the evidences that biofertilizer could reduce the use of chemical fertilizer, and the widely distributed soil in Indonesia such as Inceptisols, is potential to be used as a medium for potato production.

Meiotic transmission of Drosophila pseudoobscura chromosomal arrangements.

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Richard P Meisel

Full Text Available Drosophila pseudoobscura harbors a rich gene arrangement polymorphism on the third chromosome generated by a series of overlapping paracentric inversions. The arrangements suppress recombination in heterokaryotypic individuals, which allows for the selective maintenance of coadapted gene complexes. Previous mapping experiments used to determine the degree to which recombination is suppressed in gene arrangement heterozygotes produced non-recombinant progeny in non-Mendelian ratios. The deviations from Mendelian expectations could be the result of viability differences between wild and mutant chromosomes, meiotic drive because of achiasmate pairing of homologues in heterokaryotypic females during meiosis, or a combination of both mechanisms. The possibility that the frequencies of the chromosomal arrangements in natural populations are affected by mechanisms other than adaptive selection led us to consider these hypotheses. We performed reciprocal crosses involving both heterozygous males and females to determine if the frequency of the non-recombinant progeny deviates significantly from Mendelian expectations and if the frequencies deviate between reciprocal crosses. We failed to observe non-Mendelian ratios in multiple crosses, and the frequency of the non-recombinant classes differed in only one of five pairs of reciprocal crosses despite sufficient power to detect these differences in all crosses. Our results indicate that deviations from Mendelian expectations in recombination experiments involving the D. pseudoobscura inversion system are most likely due to fitness differences of gene arrangement karyotypes in different environments.

Impairment of the chemical defence of the beetle, Tenebrio molitor, by metacestodes (cysticeroids) of the tapeworm, Hymenolepis diminuta.

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Blankespoor, C L; Pappas, P W; Eisner, T

1997-07-01

The defensive glands of beetles, Tenebrio molitor, infected with metacestodes (cysticercoids) of Hymenolepis diminuta are everted less frequently upon stimulation, and contain less toluquinone (methylbenzoquinone) and m-cresol, than glands of uninfected controls. These differences, as shown in predation trials with wild rats, increase the likelihood that both cysticercoids and beetles will be ingested by the tapeworm's definitive host. This is the first documented case of a parasite inhibiting the chemical defence of an intermediate host, and one of only a few reports of parasite-induced manipulation of host biology supported by empirical evidence implicating facilitated parasite transmission between host species.

Genes involved in degradation of para-nitrophenol are differentially arranged in form of non-contiguous gene clusters in Burkholderia sp. strain SJ98.

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Surendra Vikram

Full Text Available Biodegradation of para-Nitrophenol (PNP proceeds via two distinct pathways, having 1,2,3-benzenetriol (BT and hydroquinone (HQ as their respective terminal aromatic intermediates. Genes involved in these pathways have already been studied in different PNP degrading bacteria. Burkholderia sp. strain SJ98 degrades PNP via both the pathways. Earlier, we have sequenced and analyzed a ~41 kb fragment from the genomic library of strain SJ98. This DNA fragment was found to harbor all the lower pathway genes; however, genes responsible for the initial transformation of PNP could not be identified within this fragment. Now, we have sequenced and annotated the whole genome of strain SJ98 and found two ORFs (viz., pnpA and pnpB showing maximum identity at amino acid level with p-nitrophenol 4-monooxygenase (PnpM and p-benzoquinone reductase (BqR. Unlike the other PNP gene clusters reported earlier in different bacteria, these two ORFs in SJ98 genome are physically separated from the other genes of PNP degradation pathway. In order to ascertain the identity of ORFs pnpA and pnpB, we have performed in-vitro assays using recombinant proteins heterologously expressed and purified to homogeneity. Purified PnpA was found to be a functional PnpM and transformed PNP into benzoquinone (BQ, while PnpB was found to be a functional BqR which catalyzed the transformation of BQ into hydroquinone (HQ. Noticeably, PnpM from strain SJ98 could also transform a number of PNP analogues. Based on the above observations, we propose that the genes for PNP degradation in strain SJ98 are arranged differentially in form of non-contiguous gene clusters. This is the first report for such arrangement for gene clusters involved in PNP degradation. Therefore, we propose that PNP degradation in strain SJ98 could be an important model system for further studies on differential evolution of PNP degradation functions.

Applications of Plackett–Burman and Central Composite Design for the Optimization of Novel Brevundimonas diminuta KT277492 Chitinase Production, Investigation of its Antifungal Activity

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E. Ashour Warda

Full Text Available ABSTRACT Biological control strategy which can damage chitin, a vital component of pathogenic fungi and arthropods promises a safe solution for many fungal problems. And it’s more favorable than chemicals which increase health risks and environmental problems. Thus, the chitinase producers appear potential candidates of biological control of pathogenic fungi. Brevundimonus diminuta KT277492 is a new isolate that has been isolated recently from Egyptian soil. Significant factors that affecting the chitinase enzyme production were studied and optimized using Plackett-Burman and Response Surface Methodology (RSM. As a result, maximum production of chitinase enzyme was 832.87 IUL-1, this result presented about 8.767-fold increase in the enzyme production. In the last phase of the study, partially purified chitinase enzyme obtained from B. diminuta KT277492 was tested against two pathogenic fungi and the results showed good inhibitory activity against A. alternata and F. solani with IZD of 31±0.25 and 25±0.91 mm respectively. Finally, obtained results indicated the value of optimization process and the optimized chitinase enzyme could be an excellent choice in application of food and biotechnology as a biofungicide. This reflects the necessity of studying the characteristics and kinetics of the enzyme in the forthcoming study.

A behavioral study of the beetle Tenebrio molitor infected with cysticercoids of the rat tapeworm Hymenolepis diminuta

Science.gov (United States)

Sheiman, I. M.; Shkutin, M. F.; Terenina, N. B.; Gustafsson, M. K. S.

2006-06-01

The host-parasite relationship, Tenebrio molitor- Hymenolepis diminuta, was analyzed. The learning behavior of infected and uninfected (control) beetles in a T-maze was compared. The infected beetles moved much slower in the T-maze than the controls. The infected beetles reached the same level of learning as the controls. However, they needed more trials than the controls. The effect of the infection was already distinct after the first week and even higher after the second week. This indicates that the initial phase of infection caused stress in the beetles. Longer infection did not worsen their ability to learn. Thus, the parasites clearly changed the behavior of their intermediate host and probably made them more susceptible to their final host, the rat.

Symbiotic Burkholderia Species Show Diverse Arrangements of nif/fix and nod Genes and Lack Typical High-Affinity Cytochrome cbb3 Oxidase Genes.

Science.gov (United States)

De Meyer, Sofie E; Briscoe, Leah; Martínez-Hidalgo, Pilar; Agapakis, Christina M; de-Los Santos, Paulina Estrada; Seshadri, Rekha; Reeve, Wayne; Weinstock, George; O'Hara, Graham; Howieson, John G; Hirsch, Ann M

2016-08-01

Genome analysis of fourteen mimosoid and four papilionoid beta-rhizobia together with fourteen reference alpha-rhizobia for both nodulation (nod) and nitrogen-fixing (nif/fix) genes has shown phylogenetic congruence between 16S rRNA/MLSA (combined 16S rRNA gene sequencing and multilocus sequence analysis) and nif/fix genes, indicating a free-living diazotrophic ancestry of the beta-rhizobia. However, deeper genomic analysis revealed a complex symbiosis acquisition history in the beta-rhizobia that clearly separates the mimosoid and papilionoid nodulating groups. Mimosoid-nodulating beta-rhizobia have nod genes tightly clustered in the nodBCIJHASU operon, whereas papilionoid-nodulating Burkholderia have nodUSDABC and nodIJ genes, although their arrangement is not canonical because the nod genes are subdivided by the insertion of nif and other genes. Furthermore, the papilionoid Burkholderia spp. contain duplications of several nod and nif genes. The Burkholderia nifHDKEN and fixABC genes are very closely related to those found in free-living diazotrophs. In contrast, nifA is highly divergent between both groups, but the papilionoid species nifA is more similar to alpha-rhizobia nifA than to other groups. Surprisingly, for all Burkholderia, the fixNOQP and fixGHIS genes required for cbb3 cytochrome oxidase production and assembly are missing. In contrast, symbiotic Cupriavidus strains have fixNOQPGHIS genes, revealing a divergence in the evolution of two distinct electron transport chains required for nitrogen fixation within the beta-rhizobia.

The complete mitochondrial genome of the sea spider Achelia bituberculata (Pycnogonida, Ammotheidae: arthropod ground pattern of gene arrangement

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Lee Yong-Seok

2007-10-01

Full Text Available Abstract Background The phylogenetic position of pycnogonids is a long-standing and controversial issue in arthropod phylogeny. This controversy has recently been rekindled by differences in the conclusions based on neuroanatomical data concerning the chelifore and the patterns of Hox expression. The mitochondrial genome of a sea spider, Nymphon gracile (Pycnogonida, Nymphonidae, was recently reported in an attempt to address this issue. However, N. gracile appears to be a long-branch taxon on the phylogenetic tree and exhibits a number of peculiar features, such as 10 tRNA translocations and even an inversion of several protein-coding genes. Sequences of other pycnogonid mitochondrial genomes are needed if the position of pycnogonids is to be elucidated on this basis. Results The complete mitochondrial genome (15,474 bp of a sea spider (Achelia bituberculata belonging to the family Ammotheidae, which combines a number of anatomical features considered plesiomorphic with respect to other pycnogonids, was sequenced and characterized. The genome organization shows the features typical of most metazoan animal genomes (37 tightly-packed genes. The overall gene arrangement is completely identical to the arthropod ground pattern, with one exception: the position of the trnQ gene between the rrnS gene and the control region. Maximum likelihood and Bayesian inference trees inferred from the amino acid sequences of mitochondrial protein-coding genes consistently indicate that the pycnogonids (A. bituberculata and N. gracile may be closely related to the clade of Acari and Araneae. Conclusion The complete mitochondrial genome sequence of A. bituberculata (Family Ammotheidae and the previously-reported partial sequence of Endeis spinosa show the gene arrangement patterns typical of arthropods (Limulus-like, but they differ markedly from that of N. gracile. Phylogenetic analyses based on mitochondrial protein-coding genes showed that Pycnogonida may be

Infection increases the value of nuptial gifts, and hence male reproductive success, in the Hymenolepis diminuta-Tenebrio molitor association.

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Hurd, Hilary; Ardin, Richard

2003-01-01

During copulation, male insects pass accessory gland components to the female with the spermatophore. These gifts can affect female reproductive behaviour, ovulation and oviposition. Here, we show that female mealworm beetles, Tenebrio molitor, mated with males infected with metacestodes of the rat tapeworm, Hymenolepis diminuta, produced significantly more offspring than those mated with uninfected males. There is a significant positive relationship between parasite intensity in the male and reproductive output in the female. Infection results in a significant increase in bean-shaped accessory gland (BAG) size. We suggest that infected males pass superior nuptial gifts to females and discuss the confounding effects of infection in male and female beetles upon overall fitness costs of infection for the host and the likelihood that the parasite is manipulating host investment in reproduction. PMID:14667373

Evaluación de una estrategia de conservación para Brevundimonas diminuta

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Nancy Burguet

2012-04-01

Full Text Available Brevundimonas diminuta se reconoce internacionalmente como el microorganismo estándar para las pruebas de reto bacteriano. El Laboratorio de Control de la Calidad de los Laboratorios Liorad dispone de una colección de cepas de referencia donde se encuentra depositada esta cepa, conservada por el método de congelación a -70oC, replicada en el medio de cultivo Caldo Lactosa Salina (CLS. Esta metodología no resultó la más conveniente, por lo que se evaluó otra estrategia de conservación para este microorganismo, donde se empleó el Caldo Triptona Soya como medio de crecimiento, la leche descremada al 20% como sustancia lioprotectora y la liofilización como método de conservación. Para verificar el sustento del cultivo se realizó un adecuado control de la calidad que incluyó la comprobación de pureza y la viabilidad y estabilidad de las propiedades de interés. Los resultados obtenidos durante los 24 meses en que se llevó a cabo el estudio de estabilidad en tiempo real confirmaron que el método elegido brindaría una alternativa y solución al problema relacionado con la conservación de esta cepa.

Structure-activity relationships in the hydrolysis of substrates by the phosphotriesterase from Pseudomonas diminuta

International Nuclear Information System (INIS)

Donarski, W.J.; Dumas, D.P.; Heitmeyer, D.P.; Lewis, V.E.; Raushel, F.M.

1989-01-01

The mechanism and substrate specificity of the phosphotriesterase from Pseudomonas diminuta have been examined. The enzyme hydrolyzes a large number of phosphotriester substrates in addition to paraoxon (diethyl p-nitrophenyl phosphate) and its thiophosphate analogue, parathion. The two ethyl groups in paraoxon can be changed to propyl and butyl groups, but the maximal velocity and Km values decrease substantially. The enzyme will not hydrolyze phosphomonoesters or -diesters. There is a linear correlation between enzymatic activity and the pKa of the phenolic leaving group for 16 paraoxon analogues. The beta value in the corresponding Bronsted plot is -0.8. No effect on either Vmax or Vmax/Km is observed when sucrose is used to increase the relative solvent viscosity by 3-fold. These results are consistent with rate-limiting phosphorus-oxygen bond cleavage. A plot of log V versus pH for the hydrolysis of paraoxon shows one enzymatic group that must be unprotonated for activity with a pKa of 6.1. The deuterium isotope effect by D2O on Vmax and Vmax/Km is 2.4 and 1.2, respectively, and the proton inventory is linear, which indicates that only one proton is in flight during the transition state. The inhibition patterns by the products are consistent with a random kinetic mechanism

Common themes and cell type specific variations of higher order chromatin arrangements in the mouse

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Cremer Thomas

2005-12-01

Full Text Available Abstract Background Similarities as well as differences in higher order chromatin arrangements of human cell types were previously reported. For an evolutionary comparison, we now studied the arrangements of chromosome territories and centromere regions in six mouse cell types (lymphocytes, embryonic stem cells, macrophages, fibroblasts, myoblasts and myotubes with fluorescence in situ hybridization and confocal laser scanning microscopy. Both species evolved pronounced differences in karyotypes after their last common ancestors lived about 87 million years ago and thus seem particularly suited to elucidate common and cell type specific themes of higher order chromatin arrangements in mammals. Results All mouse cell types showed non-random correlations of radial chromosome territory positions with gene density as well as with chromosome size. The distribution of chromosome territories and pericentromeric heterochromatin changed during differentiation, leading to distinct cell type specific distribution patterns. We exclude a strict dependence of these differences on nuclear shape. Positional differences in mouse cell nuclei were less pronounced compared to human cell nuclei in agreement with smaller differences in chromosome size and gene density. Notably, the position of chromosome territories relative to each other was very variable. Conclusion Chromosome territory arrangements according to chromosome size and gene density provide common, evolutionary conserved themes in both, human and mouse cell types. Our findings are incompatible with a previously reported model of parental genome separation.

Gene arrangement and sequence of mitochondrial genomes yield insights into the phylogeny and evolution of bees and sphecid wasps (Hymenoptera: Apoidea).

Science.gov (United States)

Zheng, Bo-Ying; Cao, Li-Jun; Tang, Pu; van Achterberg, Kees; Hoffmann, Ary A; Chen, Hua-Yan; Chen, Xue-Xin; Wei, Shu-Jun

2018-07-01

The Apoidea represent a large and common superfamily of the Hymenoptera including the bees and sphecid wasps. A robust phylogenetic tree is essential to understanding the diversity, taxonomy and evolution of the Apoidea. In this study, features of apoid mitochondrial genomes were used to reconstruct phylogenetic relationships. Twelve apoid mitochondrial genomes were newly sequenced, representing six families and nine subfamilies. Gene rearrangement events have occurred in all apoid mitochondrial genomes sequenced to date. Sphecid wasps have both tRNA and protein-coding gene rearrangements in 5 of 8 species. In bees, the only rearranged genes are tRNAs; long-tongued bees (Apidae + Megachilidae) are characterized by movement of trnA to the trnI-trnQ-trnM tRNA cluster. Phylogenetic analyses of mitochondrial gene sequences support the known paraphyly of sphecid wasps, with bees nested within this clade. The Ampulicidae is sister to the remaining Apoidea. Crabronidae is paraphyletic, split into Crabronidae s.s. and Philanthidae, with the latter group a sister clade to bees. The monophyletic bees are either classified into two clades, long-tongued bees (Apidae + Megachilidae) and short-tongued bees (Andrenidae + Halictidae + Colletidae + Melitidae), or three groups with the Melitidae sister to the other bees. Our study showed that both gene sequences and arrangements provide information on the phylogeny of apoid families. Copyright © 2018 Elsevier Inc. All rights reserved.

A balanced t(5;17 (p15;q22-23 in chondroblastoma: frequency of the re-arrangement and analysis of the candidate genes

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Wijers-Koster Pauline

2009-11-01

Full Text Available Abstract Background Chondroblastoma is a benign cartilaginous tumour of bone that predominantly affects the epiphysis of long bones in young males. No recurrent chromosomal re-arrangements have so far been observed. Methods: We identified an index case with a balanced translocation by Combined Binary Ratio-Fluorescent in situ Hybridisation (COBRA-FISH karyotyping followed by breakpoint FISH mapping and array-Comparative Genomic Hybridisation (aCGH. Candidate region re-arrangement and candidate gene expression were subsequently investigated by interphase FISH and immunohistochemistry in another 14 cases. Results A balanced t(5;17(p15;q22-23 was identified. In the index case, interphase FISH showed that the translocation was present only in mononucleated cells and was absent in the characteristic multinucleated giant cells. The t(5;17 translocation was not observed in the other cases studied. The breakpoint in 5p15 occurred close to the steroid reductase 5α1 (SRD5A1 gene. Expression of the protein was found in all cases tested. Similar expression was found for the sex steroid signalling-related molecules oestrogen receptor alpha and aromatase, while androgen receptors were only found in isolated cells in a few cases. The breakpoint in 17q22-23 was upstream of the carbonic anhydrase × (CA10 gene region and possibly involved gene-regulatory elements, which was indicated by the lack of CA10 protein expression in the index case. All other cases showed variable levels of CA10 expression, with low expression in three cases. Conclusion We report a novel t(5;17(p15;q22-23 translocation in chondroblastoma without involvement of any of the two chromosomal regions in other cases studied. Our results indicate that the characteristic multinucleated giant cells in chondroblastoma do not have the same clonal origin as the mononuclear population, as they do not harbour the same translocation. We therefore hypothesise that they might be either reactive or

A balanced t(5;17) (p15;q22-23) in chondroblastoma: frequency of the re-arrangement and analysis of the candidate genes

International Nuclear Information System (INIS)

Romeo, Salvatore; Szuhai, Karoly; Nishimori, Isao; Ijszenga, Marije; Wijers-Koster, Pauline; Taminiau, Antonie HM; Hogendoorn, Pancras CW

2009-01-01

Chondroblastoma is a benign cartilaginous tumour of bone that predominantly affects the epiphysis of long bones in young males. No recurrent chromosomal re-arrangements have so far been observed. Methods: We identified an index case with a balanced translocation by Combined Binary Ratio-Fluorescent in situ Hybridisation (COBRA-FISH) karyotyping followed by breakpoint FISH mapping and array-Comparative Genomic Hybridisation (aCGH). Candidate region re-arrangement and candidate gene expression were subsequently investigated by interphase FISH and immunohistochemistry in another 14 cases. A balanced t(5;17)(p15;q22-23) was identified. In the index case, interphase FISH showed that the translocation was present only in mononucleated cells and was absent in the characteristic multinucleated giant cells. The t(5;17) translocation was not observed in the other cases studied. The breakpoint in 5p15 occurred close to the steroid reductase 5α1 (SRD5A1) gene. Expression of the protein was found in all cases tested. Similar expression was found for the sex steroid signalling-related molecules oestrogen receptor alpha and aromatase, while androgen receptors were only found in isolated cells in a few cases. The breakpoint in 17q22-23 was upstream of the carbonic anhydrase × (CA10) gene region and possibly involved gene-regulatory elements, which was indicated by the lack of CA10 protein expression in the index case. All other cases showed variable levels of CA10 expression, with low expression in three cases. We report a novel t(5;17)(p15;q22-23) translocation in chondroblastoma without involvement of any of the two chromosomal regions in other cases studied. Our results indicate that the characteristic multinucleated giant cells in chondroblastoma do not have the same clonal origin as the mononuclear population, as they do not harbour the same translocation. We therefore hypothesise that they might be either reactive or originate from a distinct neoplastic clone, although the

The complete mitochondrial genome of Meloidogyne graminicola (Tylenchina: a unique gene arrangement and its phylogenetic implications.

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Longhua Sun

Full Text Available Meloidogyne graminicola is one of the most economically important plant parasitic-nematodes (PPNs. In the present study, we determined the complete mitochondrial (mt DNA genome sequence of this plant pathogen. Compared with other PPNs genera, this genome (19,589 bp is only slightly smaller than that of Pratylenchus vulnus (21,656 bp. The nucleotide composition of the whole mtDNA sequence of M. graminicola is significantly biased toward A and T, with T being the most favored nucleotide and C being the least favored. The A+T content of the entire genome is 83.51%. The mt genome of M. graminicola contains 36 genes (lacking atp8 that are transcribed in the same direction. The gene arrangement of the mt genome of M. graminicola is unique. A total of 21 out of 22 tRNAs possess a DHU loop only, while tRNASer(AGN lacks a DHU loop. The two large noncoding regions (2,031 bp and 5,063 bp are disrupted by tRNASer(UCN. Phylogenetic analysis based on concatenated amino acid sequences of 12 protein-coding genes support the monophylies of the three orders Rhabditida, Mermithida and Trichinellida, the suborder Rhabditina and the three infraorders Spiruromorpha, Oxyuridomorpha and Ascaridomorpha, but do not support the monophylies of the two suborders Spirurina and Tylenchina, and the three infraorders Rhabditomorpha, Panagrolaimomorpha and Tylenchomorpha. The four Tylenchomorpha species including M. graminicola, P. vulnus, H. glycines and R. similis from the superfamily Tylenchoidea are placed within a well-supported monophyletic clade, but far from the other two Tylenchomorpha species B. xylophilus and B. mucronatus of Aphelenchoidea. In the clade of Tylenchoidea, M. graminicola is sister to P. vulnus, and H. glycines is sister to R. similis, which suggests root-knot nematodes has a closer relationship to Pratylenchidae nematodes than to cyst nematodes.

Human genes for complement components C1r and C1s in a close tail-to-tail arrangement

International Nuclear Information System (INIS)

Kusumoto, H.; Hirosawa, S.; Salier, J.P.; Hagen, F.S.; Kurachi, K.

1988-01-01

Complementary DNA clones for human C1s were isolated from cDNA libraries that were prepared with poly(A) + RNAs of human liver and HepG2 cells. A clone with the largest cDNA insert of 2,664 base pairs (bp) was analyzed for its complete nucleotide sequence. It contained 202 bp of a 5' untranslated region, 45 bp of coding for a signal peptide (15 amino acid residues), 2,019 bp for complement component C1s zymogen (673 amino acid residues), 378 bp for a 3' untranslated region, a stop codon, and 17 bp of a poly(A) tail. The amino acid sequence of C1s was 40.5% identical to that of C1r, with excellent matches of tentative disulfide bond locations conserving the overall domain structure of C1r. DNA blotting and sequencing analyses of genomic DNA and of an isolated genomic DNA clone clearly showed that the human genes for C1r and C1s are closely located in a tail-to-tail arrangement at a distance of about 9.5 kilobases. Furthermore, RNA blot analyses showed that both C1r and C1s genes are primarily expressed in liver, whereas most other tissues expressed both C1r and C1s genes at much lower levels (less than 10% of that in liver). Multiple molecular sizes of specific mRNAs were observed in the RNA blot analyses for both C1r and C1s, indicating that alternative RNA processing(s), likely an alternative polyadenylylation, might take place for both genes

par genes in Mycobacterium bovis and Mycobacterium smegmatis are arranged in an operon transcribed from "SigGC" promoters

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Casart Yveth

2008-03-01

Full Text Available Abstract Background The ParA/Soj and ParB/Spo0J proteins, and the cis-acting parS site, participate actively in chromosome segregation and cell cycle progression. Genes homologous to parA and parB, and two putative parS copies, have been identified in the Mycobacterium bovis BCG and Mycobacterium smegmatis chromosomes. As in Mycobacterium tuberculosis, the parA and parB genes in these two non-pathogenic mycobacteria are located near the chromosomal origin of replication. The present work focused on the determination of the transcriptional organisation of the ~6 Kb orf60K-parB region of M. bovis BCG and M. smegmatis by primer extension, transcriptional fusions to the green fluorescence protein (GFP and quantitative RT-PCR. Results The parAB genes were arranged in an operon. However, we also found promoters upstream of each one of these genes. Seven putative promoter sequences were identified in the orf60K-parB region of M. bovis BCG, whilst four were identified in the homologous region of M. smegmatis, one upstream of each open reading frame (ORF. Real-time PCR assays showed that in M. smegmatis, mRNA-parA and mRNA-parB levels decreased between the exponential and stationary phases. In M. bovis BCG, mRNA-parA levels also decreased between the exponential and stationary phases. However, parB expression was higher than parA expression and remained almost unchanged along the growth curve. Conclusion The majority of the proposed promoter regions had features characteristic of Mycobacterium promoters previously denoted as Group D. The -10 hexamer of a strong E. coli σ70-like promoter, located upstream of gidB of M. bovis BCG, overlapped with a putative parS sequence, suggesting that the transcription from this promoter might be regulated by the binding of ParB to parS.

On arrangements of pseudohyperplanes

Indian Academy of Sciences (India)

To every realizable oriented matroid there corresponds an arrangement of ... An important object missing in the context of pseudo-arrangements is an analogue ...... to extend this correspondence we use the language of metrical-hemisphere ...

Voluntary Environmental Governance Arrangements

NARCIS (Netherlands)

van der Heijden, J.

2012-01-01

Voluntary environmental governance arrangements have focal attention in studies on environmental policy, regulation and governance. The four major debates in the contemporary literature on voluntary environmental governance arrangements are studied. The literature falls short of sufficiently

Optical Arrangement and Method

DEFF Research Database (Denmark)

2010-01-01

Processing of electromagnetic radiation is described, said incoming electromagnetic radiation comprising radiation in a first wavelength interval and a plurality of spatial frequencies. An arrangement comprises a focusing arrangement for focusing the incoming electromagnetic radiation, a first ca...

Topics in hyperplane arrangements

CERN Document Server

Aguiar, Marcelo

2017-01-01

This monograph studies the interplay between various algebraic, geometric and combinatorial aspects of real hyperplane arrangements. It provides a careful, organized and unified treatment of several recent developments in the field, and brings forth many new ideas and results. It has two parts, each divided into eight chapters, and five appendices with background material. Part I gives a detailed discussion on faces, flats, chambers, cones, gallery intervals, lunes and other geometric notions associated with arrangements. The Tits monoid plays a central role. Another important object is the category of lunes which generalizes the classical associative operad. Also discussed are the descent and lune identities, distance functions on chambers, and the combinatorics of the braid arrangement and related examples. Part II studies the structure and representation theory of the Tits algebra of an arrangement. It gives a detailed analysis of idempotents and Peirce decompositions, and connects them to the classical th...

Rotary kiln arrangements

International Nuclear Information System (INIS)

Hayes, M.R.

1983-01-01

In a rotary kiln arrangement in which a reaction is to occur between counterflowing reactants and material is discharged through a hopper, an injector for at least one reactant extends into a reaction zone of the kiln, means being provided for the reaction zone to be maintained within a desired temperature range. The said means includes heating elements for adjusting the temperature of the injected reactant to a temperature within the desired range while it is in the injector. The arrangement may be used in the production of uranium oxides from uranium hexafluoride. (author)

42 CFR 413.241 - Pharmacy arrangements.

Science.gov (United States)

2010-10-01

... 42 Public Health 2 2010-10-01 2010-10-01 false Pharmacy arrangements. 413.241 Section 413.241... Disease (ESRD) Services and Organ Procurement Costs § 413.241 Pharmacy arrangements. Effective January 1, 2011, an ESRD facility that enters into an arrangement with a pharmacy to furnish renal dialysis...

29 CFR 779.229 - Other arrangements.

Science.gov (United States)

2010-07-01

..., Franchise and Other Business Arrangements § 779.229 Other arrangements. With respect to those arrangements...” establishment will be considered a part of the same “enterprise.” For example, whether a franchise, lease, or... the enterprise which grants the franchise, right, or concession. (S. Rept. 145, 87th Cong., 1st Sess...

Correlation analysis of fracture arrangement in space

Science.gov (United States)

Marrett, Randall; Gale, Julia F. W.; Gómez, Leonel A.; Laubach, Stephen E.

2018-03-01

We present new techniques that overcome limitations of standard approaches to documenting spatial arrangement. The new techniques directly quantify spatial arrangement by normalizing to expected values for randomly arranged fractures. The techniques differ in terms of computational intensity, robustness of results, ability to detect anti-correlation, and use of fracture size data. Variation of spatial arrangement across a broad range of length scales facilitates distinguishing clustered and periodic arrangements-opposite forms of organization-from random arrangements. Moreover, self-organized arrangements can be distinguished from arrangements due to extrinsic organization. Traditional techniques for analysis of fracture spacing are hamstrung because they account neither for the sequence of fracture spacings nor for possible coordination between fracture size and position, attributes accounted for by our methods. All of the new techniques reveal fractal clustering in a test case of veins, or cement-filled opening-mode fractures, in Pennsylvanian Marble Falls Limestone. The observed arrangement is readily distinguishable from random and periodic arrangements. Comparison of results that account for fracture size with results that ignore fracture size demonstrates that spatial arrangement is dominated by the sequence of fracture spacings, rather than coordination of fracture size with position. Fracture size and position are not completely independent in this example, however, because large fractures are more clustered than small fractures. Both spatial and size organization of veins here probably emerged from fracture interaction during growth. The new approaches described here, along with freely available software to implement the techniques, can be applied with effect to a wide range of structures, or indeed many other phenomena such as drilling response, where spatial heterogeneity is an issue.

Living Arrangements of Young Adults in Europe

Directory of Open Access Journals (Sweden)

Katrin Schwanitz

2015-12-01

Full Text Available Comparative research suggests that there are great cross-national and cross-temporal differences in living arrangements of young adults aged 18-34 in Europe. In this paper, we examine young adults’ living arrangements (1 across several European countries and different national contexts, and (2 by taking into account cross-time variability. In doing so, we pay careful attention to a comprehensive conceptualisation of living arrangements (including extended and non-family living arrangements. The aim of this paper is to deepen our understanding of family structure and household arrangements in Europe by examining and mapping the cross-national and cross-temporal variety of young adults’ living arrangements. For our analysis we use data from the Integrated Public Use Microdata Series International (IPUMSi for the census rounds 1980, 1990, and 2000 for eight European countries (Austria, France, Greece, Hungary, Ireland, Portugal, Romania, and Switzerland. We employ log-linear models to ascertain the influence of individual and contextual factors on living arrangements. The analyses lend further support to a North/West – South/East divide in living arrangements and general gender differentials in extended family living. Other interesting results are the heterogeneity in the living arrangements of single mothers across geographic areas, and the upward trend of extended household living for young men and women between 1980 and 2000.

National arrangements for radiotherapy

International Nuclear Information System (INIS)

2007-01-01

After a presentation of several letters exchanged between the French health ministry and public agencies in charge of public health or nuclear safety after a radiotherapy accident in Epinal, this report comments the evolution of needs in cancerology care and the place given to radiotherapy. It outlines the technological and organisational evolution of radiotherapy and presents the distribution of radiotherapy equipment, of radio-therapists and other radiotherapy professionals in France. Within the context of radiotherapy accidents which occurred in 2007, it presents the regulatory arrangements which aimed at improving the safety, short term and middle term arrangements which are needed to support and structure radiotherapy practice quality. It stresses the fact that the system will deeply evolve by implementing a radiotherapy vigilance arrangement and a permanent follow-on and adaptation plan based on surveys and the creation of a national committee

46 CFR 180.150 - Survival craft embarkation arrangements.

Science.gov (United States)

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft embarkation arrangements. 180.150 Section... (UNDER 100 GROSS TONS) LIFESAVING EQUIPMENT AND ARRANGEMENTS Survival Craft Arrangements and Equipment § 180.150 Survival craft embarkation arrangements. (a) A launching appliance approved under approval...

Flexible Working Time Arrangements in Bulgaria

OpenAIRE

Beleva, Iskra

2009-01-01

The objective of this paper is to analyze the flexible working time arrangements in Bulgaria, using a life-course perspective. Two important features have to be outlined, namely: underdeveloped flexible forms of employment in the country, including working time arrangement, and lack of previous analysis on flexible working time arrangements from the angle of life-course perspective. The author describes the regulatory framework, collective agreements at national and company level as a frame w...

48 CFR 28.304 - Risk-pooling arrangements.

Science.gov (United States)

2010-10-01

... CONTRACTING REQUIREMENTS BONDS AND INSURANCE Insurance 28.304 Risk-pooling arrangements. Agencies may establish risk-pooling arrangements. These arrangements are designed to use the services of the insurance industry for safety engineering and the handling of claims at minimum cost to the Government. The agency...

Sealing arrangement for radioactive material

International Nuclear Information System (INIS)

Gray, I.L.S.; Sievwright, R.W.T.; Elliott, J.C.

1993-01-01

A sealing arrangement for hermetically sealing two mating surfaces comprises two seals arranged to lie between the surfaces. Each seal provides hermetic sealing over a respective different temperature range and lie serially along the surfaces between the regions to be isolated. A main seal integrity test arrangement is provided in the form of a port and passage. This allows for the introduction of a fluid into or the evacuation of a region between the two seals to detect a leak. The port is also provided with at least two test port seals which seal with a plug. The plug is also provided with a test port to allow the integrity of the test port seal to be tested. (UK)

Classic romance in electronic arrangement

Directory of Open Access Journals (Sweden)

Kizin M.M.

2017-03-01

Full Text Available this article analyses the transformation of the performing arts of classical romance in the terms of electronic sound and performance via electronic sounds arrangements. The author focuses on the problem of synthesis of electronic sound arrangements and classical romance, offering to acquire the skills of the creative process in constantly changing conditions of live performances.

Tandemly arranged chalcone synthase A genes contribute to the spatially regulated expression of siRNA and the natural bicolor floral phenotype in Petunia hybrida.

Science.gov (United States)

Morita, Yasumasa; Saito, Ryoko; Ban, Yusuke; Tanikawa, Natsu; Kuchitsu, Kazuyuki; Ando, Toshio; Yoshikawa, Manabu; Habu, Yoshiki; Ozeki, Yoshihiro; Nakayama, Masayoshi

2012-06-01

The natural bicolor floral traits of the horticultural petunia (Petunia hybrida) cultivars Picotee and Star are caused by the spatial repression of the chalcone synthase A (CHS-A) gene, which encodes an anthocyanin biosynthetic enzyme. Here we show that Picotee and Star petunias carry the same short interfering RNA (siRNA)-producing locus, consisting of two intact CHS-A copies, PhCHS-A1 and PhCHS-A2, in a tandem head-to-tail orientation. The precursor CHS mRNAs are transcribed from the two CHS-A copies throughout the bicolored petals, but the mature CHS mRNAs are not found in the white tissues. An analysis of small RNAs revealed the accumulation of siRNAs of 21 nucleotides that originated from the exon 2 region of both CHS-A copies. This accumulation is closely correlated with the disappearance of the CHS mRNAs, indicating that the bicolor floral phenotype is caused by the spatially regulated post-transcriptional silencing of both CHS-A genes. Linkage between the tandemly arranged CHS-A allele and the bicolor floral trait indicates that the CHS-A allele is a necessary factor to confer the trait. We suppose that the spatially regulated production of siRNAs in Picotee and Star flowers is triggered by another putative regulatory locus, and that the silencing mechanism in this case may be different from other known mechanisms of post-transcriptional gene silencing in plants. A sequence analysis of wild Petunia species indicated that these tandem CHS-A genes originated from Petunia integrifolia and/or Petunia inflata, the parental species of P. hybrida, as a result of a chromosomal rearrangement rather than a gene duplication event. © 2012 The Authors. The Plant Journal © 2012 Blackwell Publishing Ltd.

22 CFR 92.63 - Arrangement of papers.

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Arrangement of papers. 92.63 Section 92.63... and Letters Rogatory § 92.63 Arrangement of papers. Unless special instructions to the contrary are received, the various papers comprising the completed record of the depositions should usually be arranged...

Renewable energy and Scottish trading arrangements

International Nuclear Information System (INIS)

2001-01-01

This report summarises the findings of a project involving the participation of the Scottish Renewables Forum (SRF) in the ongoing Ofgem consultation process concerning the future electricity trading arrangements in Scotland. The present administrative arrangements, the activities of the SRF, the prospects for the British Electricity Trading and Transmission Arrangements (BETTA), generator connection policy, and transmission access are discussed, and an overview of consultations relating to Scotland-England interconnection access is presented. The appendices cover the SRF responses to the Ofgem consultation, a discussion paper in advance of the SRF meeting with Ofgem in April 2001, an SRF trading update, the SRF's responses to Ofgem's Environmental Action Plan, the Scottish Embedded Generators Working Group's terms of reference and draft paper on issues, and a briefing on prices in administered arrangements

Plutonium, power, and politics: international arrangements for the disposition of spent nuclear fuel

International Nuclear Information System (INIS)

Rochlin, G.I.

1979-01-01

In this study, Gene Rochlin, physicist and social scientist, explores the technical, political, and institutional aspects of international nuclear export and fuel-cycle policies. He categorizes existing proposals and suggests ways to develop new ones that better promote both national and international goals. Dr. Rochlin argues neither for nor against the future use of nuclear power or plutonium fuels. Rather, he addresses the question of how international arrangements could be reached that might jointly satisfy the objectives of the several key nations, yet not be too difficult to negotiate. He concludes that a major fault has been the tendency to improvise arrangements for specific technical or industrial operations. As a result, overall social and political goals have become the bargaining points for compromise. Yet, attempts to simultaneously resolve all problems are unlikely to prove fruitful. Dr. Rochlin suggests instead the formation of institutions organized around more-limited social, political, and technical objectives - even at the expense of excluding some nations, or omitting some aspects of the nuclear fuel cycle. Only by so doing, he argues, can immediate agreements be reached that preserve the potential for more-comprehensive future arrangements without sacrificing industrial, environmental, or nonproliferation goals

Peak load arrangements : Assessment of Nordel guidelines

Energy Technology Data Exchange (ETDEWEB)

2009-07-01

Two Nordic countries, Sweden and Finland, have legislation that empowers the TSO to acquire designated peak load resources to mitigate the risk for shortage situations during the winter. In Denmark, the system operator procures resources to maintain a satisfactory level of security of supply. In Norway the TSO has set up a Regulation Power Option Market (RKOM) to secure a satisfactory level of operational reserves at all times, also in winter with high load demand. Only the arrangements in Finland and Sweden fall under the heading of Peak Load Arrangements defined in Nordel Guidelines. NordREG has been invited by the Electricity Market Group (EMG) to evaluate Nordel's proposal for 'Guidelines for transitional Peak Load Arrangements'. The EMG has also financed a study made by EC Group to support NordREG in the evaluation of the proposal. The study has been taken into account in NordREG's evaluation. In parallel to the EMG task, the Swedish regulator, the Energy Markets Inspectorate, has been given the task by the Swedish government to investigate a long term solution of the peak load issue. The Swedish and Finnish TSOs have together with Nord Pool Spot worked on finding a harmonized solution for activation of the peak load reserves in the market. An agreement accepted by the relevant authorities was reached in early January 2009, and the arrangement has been implemented since 19th January 2009. NordREG views that the proposed Nordel guidelines have served as a starting point for the presently agreed procedure. However, NordREG does not see any need to further develop the Nordel guidelines for peak load arrangements. NordREG agrees with Nordel that the market should be designed to solve peak load problems through proper incentives to market players. NordREG presumes that the relevant authorities in each country will take decisions on the need for any peak load arrangement to ensure security of supply. NordREG proposes that such decisions should be

Modelling the development and arrangement of the primary vascular structure in plants.

Science.gov (United States)

Cartenì, Fabrizio; Giannino, Francesco; Schweingruber, Fritz Hans; Mazzoleni, Stefano

2014-09-01

The process of vascular development in plants results in the formation of a specific array of bundles that run throughout the plant in a characteristic spatial arrangement. Although much is known about the genes involved in the specification of procambium, phloem and xylem, the dynamic processes and interactions that define the development of the radial arrangement of such tissues remain elusive. This study presents a spatially explicit reaction-diffusion model defining a set of logical and functional rules to simulate the differentiation of procambium, phloem and xylem and their spatial patterns, starting from a homogeneous group of undifferentiated cells. Simulation results showed that the model is capable of reproducing most vascular patterns observed in plants, from primitive and simple structures made up of a single strand of vascular bundles (protostele), to more complex and evolved structures, with separated vascular bundles arranged in an ordered pattern within the plant section (e.g. eustele). The results presented demonstrate, as a proof of concept, that a common genetic-molecular machinery can be the basis of different spatial patterns of plant vascular development. Moreover, the model has the potential to become a useful tool to test different hypotheses of genetic and molecular interactions involved in the specification of vascular tissues.

Seal arrangement

International Nuclear Information System (INIS)

Dempsey, J.D.

1978-01-01

A hydraulically balanced face type shaft seal is provided in which the opening and closing seal face areas retain concentricity with each other in the event of lateral shaft displacement. The seal arrangement is for a vertical high pressure pump, indented for use in the cooling system of a nuclear reactor. (Auth.)

Nuclear reactor internals arrangement

International Nuclear Information System (INIS)

Frisch, E.; Andrews, H.N.

1976-01-01

A nuclear reactor internals arrangement is disclosed which facilitates reactor refueling. A reactor vessel and a nuclear core is utilized in conjunction with an upper core support arrangement having means for storing withdrawn control rods therein. The upper core support is mounted to the underside of the reactor vessel closure head so that upon withdrawal of the control rods into the upper core support, the closure head, the upper core support and the control rods are removed as a single unit thereby directly exposing the core for purposes of refueling

IAEA paper on institutional arrangements

International Nuclear Information System (INIS)

1979-01-01

At its fifth series of meetings, Working Group 3 received a background paper prepared by the IAEA which had a threefold purpose: firstly, to provide an overview on institutional arrangements under consideration by the INFCE Working Groups; secondly, to explore potential relationships between the various institutional arrangements under consideration; and thirdly, to identify areas where further analysis might be desirable

Living arrangements and mental health in Finland

Science.gov (United States)

Joutsenniemi, Kaisla; Martelin, Tuija; Martikainen, Pekka; Pirkola, Sami; Koskinen, Seppo

2006-01-01

Background Non‐married persons are known to have poor mental health compared with married persons. Health differences between marital status groups may largely arise from corresponding differences in interpersonal social bonds. However, official marital status mirrors the social reality of persons to a decreasing extent, and living arrangements may be a better measure of social bonds. Little is known about mental health in different living arrangement groups. This study aims to establish the extent and determinants of mental health differences by living arrangement in terms of psychological distress (GHQ) and DSM‐IV psychiatric disorders (CIDI). Methods Data were used from the nationally representative cross sectional health 2000 survey, conducted in 2000–1 in Finland. Altogether 4685 participants (80%) aged 30–64 years were included in these analyses; comprehensive information was available on measures of mental health and living arrangements. Living arrangements were measured as follows: married, cohabiting, living with other(s) than a partner, and living alone. Results Compared with the married, persons living alone and those living with other(s) than a partner were approximately twice as likely to have anxiety or depressive disorders. Cohabiters did not differ from the married. In men, psychological distress was similarly associated with living arrangements. Unemployment, lack of social support, and alcohol consumption attenuated the excess psychological distress and psychiatric morbidity of persons living alone and of those living with other(s) than a partner by about 10%–50% each. Conclusions Living arrangements are strongly associated with mental health, particularly among men. Information on living arrangements, social support, unemployment, and alcohol use may facilitate early stage recognition of poor mental health in primary health care. PMID:16698975

The Politics of Legal Arrangements

DEFF Research Database (Denmark)

Leander, Anna

2018-01-01

This article explores the place of formal legal arrangements in the politics surrounding the hybrid, enmeshed public-in-the-private forms of authority this special issue focuses on. It does so by analyzing the significance of one specific legal arrangement, the Duty of Care, for the politics...... and divisions currently organizing debates about the regulation of commercial security as well as about managerialism in international law more generally....

Contingent and Alternative Work Arrangements, Defined.

Science.gov (United States)

Polivka, Anne E.

1996-01-01

Discusses the definitions of contingent workers and alternative work arrangements used by the Bureau of Labor Statistics to analyze data, and presents aggregate estimates of the number of workers in each group. Discusses the overlap between contingent workers and workers in alternative arrangements. (Author/JOW)

46 CFR 195.06-1 - Lifesaving appliances and arrangements.

Science.gov (United States)

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Lifesaving appliances and arrangements. 195.06-1 Section... VESSELS VESSEL CONTROL AND MISCELLANEOUS SYSTEMS AND EQUIPMENT Lifesaving Appliances and Arrangements § 195.06-1 Lifesaving appliances and arrangements. All lifesaving appliances and arrangements shall be...

Flood risk governance arrangements in Europe

Science.gov (United States)

Matczak, P.; Lewandowski, J.; Choryński, A.; Szwed, M.; Kundzewicz, Z. W.

2015-06-01

The STAR-FLOOD (Strengthening and Redesigning European Flood Risk Practices Towards Appropriate and Resilient Flood Risk Governance Arrangements) project, funded by the European Commission, investigates strategies for dealing with flood risk in six European countries: Belgium, the UK, France, the Netherlands, Poland and Sweden and in 18 vulnerable urban regions in these countries. The project aims to describe, analyse, explain, and evaluate the main similarities and differences between the selected EU Member States in terms of development and performance of flood risk governance arrangements. It also discusses the scientific and societal importance of these similarities and differences. Attention is paid to identification and characterization of shifts in flood risk governance arrangements and in flood risk management strategies and to determination of triggering factors and restraining factors. An assessment of a change of resilience and appropriateness (legitimacy, effectiveness, efficiency) of flood risk governance arrangements in Poland is presented and comparison with other European countries is offered.

Flood risk governance arrangements in Europe

Directory of Open Access Journals (Sweden)

P. Matczak

2015-06-01

Full Text Available The STAR-FLOOD (Strengthening and Redesigning European Flood Risk Practices Towards Appropriate and Resilient Flood Risk Governance Arrangements project, funded by the European Commission, investigates strategies for dealing with flood risk in six European countries: Belgium, the UK, France, the Netherlands, Poland and Sweden and in 18 vulnerable urban regions in these countries. The project aims to describe, analyse, explain, and evaluate the main similarities and differences between the selected EU Member States in terms of development and performance of flood risk governance arrangements. It also discusses the scientific and societal importance of these similarities and differences. Attention is paid to identification and characterization of shifts in flood risk governance arrangements and in flood risk management strategies and to determination of triggering factors and restraining factors. An assessment of a change of resilience and appropriateness (legitimacy, effectiveness, efficiency of flood risk governance arrangements in Poland is presented and comparison with other European countries is offered.

Entry into and Consequences of Nonstandard Work Arrangements.

Science.gov (United States)

Rothstein, Donna S.

1996-01-01

Explores the impact on workers of being in a nonstandard employment arrangement. Examines the distribution of workers among various arrangements and looks at aspects of work behavior and life events that may have influenced their working in a nonstandard arrangement. (Author/JOW)

Determinants of flexible work arrangements

OpenAIRE

Sarbu, Miruna

2014-01-01

Flexible work arrangements such as allowing employees to work at home are used in firms, especially since information and communication technologies have become so widespread. Using individual-level data from 10,884 German employees, this paper analyses the determinants of working at home as a form of flexible work arrangements. The analysis is based on descriptive analyses and a discrete choice model using a probit estimation approach. The results reveal that men have a higher...

46 CFR 188.27-1 - Lifesaving appliances and arrangements.

Science.gov (United States)

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Lifesaving appliances and arrangements. 188.27-1 Section... VESSELS GENERAL PROVISIONS Lifesaving Appliances and Arrangements § 188.27-1 Lifesaving appliances and arrangements. All lifesaving appliances and arrangements shall be in accordance with the requirements for...

46 CFR 90.27-1 - Lifesaving appliances and arrangements.

Science.gov (United States)

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Lifesaving appliances and arrangements. 90.27-1 Section... VESSELS GENERAL PROVISIONS Lifesaving Appliances and Arrangements § 90.27-1 Lifesaving appliances and arrangements. All lifesaving appliances and arrangements must be in accordance with subchapter W (Lifesaving...

46 CFR 70.28-1 - Lifesaving appliances and arrangements.

Science.gov (United States)

2010-10-01

... 46 Shipping 3 2010-10-01 2010-10-01 false Lifesaving appliances and arrangements. 70.28-1 Section... PROVISIONS Lifesaving Appliances and Arrangements § 70.28-1 Lifesaving appliances and arrangements. All lifesaving appliances and arrangements on passenger vessels must be in accordance with subchapter W...

78 FR 40131 - Proposed Subsequent Arrangement

Science.gov (United States)

2013-07-03

... INFORMATION: This subsequent arrangement concerns the retransfer of 302,188 kg of U.S.-origin natural uranium..., Saskatchewan, Canada, to Springfields Fuels Ltd. in Lancashire, United Kingdom. The material, which is... arrangement concerning the retransfer of nuclear material of United States origin will not be inimical to the...

European top managers' support for work-life arrangements

NARCIS (Netherlands)

Been, W.M.|info:eu-repo/dai/nl/357424662

2015-01-01

In recent decades, work-life arrangements increasingly became an integral part of the organization of work. Arrangements such as telecommuting, flextime, part-time hours, and various types of leave arrangements are available to employees in many organizations. Top managers, such as CEOs, CFOs and

47 CFR 1.9020 - Spectrum manager leasing arrangements.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 1 2010-10-01 2010-10-01 false Spectrum manager leasing arrangements. 1.9020... Leasing General Policies and Procedures § 1.9020 Spectrum manager leasing arrangements. (a) Overview... may enter into a spectrum manager leasing arrangement, without the need for prior Commission approval...

Best connected rectangular arrangements

Directory of Open Access Journals (Sweden)

Krishnendra Shekhawat

2016-03-01

Full Text Available It can be found quite often in the literature that many well-known architects have employed either the golden rectangle or the Fibonacci rectangle in their works. On contrary, it is rare to find any specific reason for using them so often. Recently, Shekhawat (2015 proved that the golden rectangle and the Fibonacci rectangle are one of the best connected rectangular arrangements and this may be one of the reasons for their high presence in architectural designs. In this work we present an algorithm that generates n-4 best connected rectangular arrangements so that the proposed solutions can be further used by architects for their designs.

A benign helminth alters the host immune system and the gut microbiota in a rat model system.

Directory of Open Access Journals (Sweden)

Laura Wegener Parfrey

Full Text Available Helminths and bacteria are major players in the mammalian gut ecosystem and each influences the host immune system and health. Declines in helminth prevalence and bacterial diversity appear to play a role in the dramatic rise of immune mediated inflammatory diseases (IMIDs in western populations. Helminths are potent modulators of immune system and their reintroduction is a promising therapeutic avenue for IMIDs. However, the introduction of helminths represents a disturbance for the host and it is important to understand the impact of helminth reintroduction on the host, including the immune system and gut microbiome. We tested the impact of a benign tapeworm, Hymenolepis diminuta, in a rat model system. We find that H. diminuta infection results in increased interleukin 10 gene expression in the beginning of the prepatent period, consistent with induction of a type 2 immune response. We also find induction of humoral immunity during the patent period, shown here by increased IgA in feces. Further, we see an immuno-modulatory effect in the small intestine and spleen in patent period, as measured by reductions in tissue immune cells. We observed shifts in microbiota community composition during the patent period (beta-diversity in response to H. diminuta infection. However, these compositional changes appear to be minor; they occur within families and genera common to both treatment groups. There was no change in alpha diversity. Hymenolepis diminuta is a promising model for helminth therapy because it establishes long-term, stable colonization in rats and modulates the immune system without causing bacterial dysbiosis. These results suggest that the goal of engineering a therapeutic helminth that can safely manipulate the mammalian immune system without disrupting the rest of the gut ecosystem is in reach.

A benign helminth alters the host immune system and the gut microbiota in a rat model system.

Science.gov (United States)

Wegener Parfrey, Laura; Jirků, Milan; Šíma, Radek; Jalovecká, Marie; Sak, Bohumil; Grigore, Karina; Jirků Pomajbíková, Kateřina

2017-01-01

Helminths and bacteria are major players in the mammalian gut ecosystem and each influences the host immune system and health. Declines in helminth prevalence and bacterial diversity appear to play a role in the dramatic rise of immune mediated inflammatory diseases (IMIDs) in western populations. Helminths are potent modulators of immune system and their reintroduction is a promising therapeutic avenue for IMIDs. However, the introduction of helminths represents a disturbance for the host and it is important to understand the impact of helminth reintroduction on the host, including the immune system and gut microbiome. We tested the impact of a benign tapeworm, Hymenolepis diminuta, in a rat model system. We find that H. diminuta infection results in increased interleukin 10 gene expression in the beginning of the prepatent period, consistent with induction of a type 2 immune response. We also find induction of humoral immunity during the patent period, shown here by increased IgA in feces. Further, we see an immuno-modulatory effect in the small intestine and spleen in patent period, as measured by reductions in tissue immune cells. We observed shifts in microbiota community composition during the patent period (beta-diversity) in response to H. diminuta infection. However, these compositional changes appear to be minor; they occur within families and genera common to both treatment groups. There was no change in alpha diversity. Hymenolepis diminuta is a promising model for helminth therapy because it establishes long-term, stable colonization in rats and modulates the immune system without causing bacterial dysbiosis. These results suggest that the goal of engineering a therapeutic helminth that can safely manipulate the mammalian immune system without disrupting the rest of the gut ecosystem is in reach.

Arranged marriages annulled by law.

Science.gov (United States)

Zhu, H

1996-06-01

The arranged marriages of 210 young people in Yongle Town in Zunyi County of Guizhou Province were dissolved in 1995. The proportion of child betrothals, which generally happens among close relatives, is as high as 85% in the town. Some engagements, known as fetus betrothals or belt betrothals, are arranged before the children are born or while they are still infants strapped (belted) to their mothers. Dissemination of information from the Constitution, the Marriage Law, and the Regulations on the Registration of Marriage concerning marriage, healthier births, and good upbringing of children, and other information on reproductive health, has shown young people that they have the freedom to love and marry of their own free will, that their marriage is protected by law, and that consanguineous marriage is harmful to the health of future generations. Some convinced their parents that their arranged marriages should be annulled.

Storage arrangements for nuclear fuel

International Nuclear Information System (INIS)

Deacon, D.

1982-01-01

A storage arrangement for spent nuclear fuel either irradiated or pre-irradiated or for vitrified waste after spent fuel reprocessing, comprises a plenum chamber which has a base pierced by a plurality of openings each of which has sealed to it an open topped tube extending downwards and closed at its lower end. The plenum chamber, with the tubes, forms an air-filled enclosure associated with an exhaust system for exhausting air from the system through filters to maintain the interior of the enclosure at sub-atmospheric pressure. The tubes are arranged to accommodate the stored fuel and the arrangement includes a means for producing a flow of cooling air over the exterior of the tubes so that the latter effectively form a plurality of heat exchangers in close proximity to the fuel. The air may be caused to flow over the tube surfaces by a natural thermosyphon process. (author)

46 CFR 117.150 - Survival craft embarkation arrangements.

Science.gov (United States)

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Survival craft embarkation arrangements. 117.150 Section... EQUIPMENT AND ARRANGEMENTS Survival Craft Arrangements and Equipment § 117.150 Survival craft embarkation... apparatus when either— (1) The embarkation station for the survival craft is on a deck more than 4.5 meters...

Orientation, distance, regulation and function of neighbouring genes

Directory of Open Access Journals (Sweden)

Gherman Adrian

2009-01-01

Full Text Available Abstract The sequencing of the human genome has allowed us to observe globally and in detail the arrangement of genes along the chromosomes. There are multiple lines of evidence that this arrangement is not random, both in terms of intergenic distances and orientation of neighbouring genes. We have undertaken a systematic evaluation of the spatial distribution and orientation of known genes across the human genome. We used genome-level information, including phylogenetic conservation, single nucleotide polymorphism density and correlation of gene expression to assess the importance of this distribution. In addition to confirming and extending known properties of the genome, such as the significance of gene deserts and the importance of 'head to head' orientation of gene pairs in proximity, we provide significant new observations that include a smaller average size for intervals separating the 3' ends of neighbouring genes, a correlation of gene expression across tissues for genes as far as 100 kilobases apart and signatures of increasing positive selection with decreasing interval size surprisingly relaxing for intervals smaller than ~500 base pairs. Further, we provide extensive graphical representations of the genome-wide data to allow for observations and comparisons beyond what we address.

Percentage compensation arrangements: suspect, but not illegal.

Science.gov (United States)

Fedor, F P

2001-01-01

Percentage compensation arrangements, in which a service is outsourced to a contractor that is paid in accordance with the level of its performance, are widely used in many business sectors. The HHS Office of Inspector General (OIG) has shown concern that these arrangements in the healthcare industry may offer incentives for the performance of unnecessary services or cause false claims to be made to Federal healthcare programs in violation of the antikickback statute and the False Claims Act. Percentage compensation arrangements can work and need not run afoul of the law as long as the healthcare organization carefully oversees the arrangement and sets specific safeguards in place. These safeguards include screening contractors, carefully evaluating their compliance programs, and obligating them contractually to perform within the limits of the law.

Spatial arrangement of faults and opening-mode fractures

Science.gov (United States)

Laubach, S. E.; Lamarche, J.; Gauthier, B. D. M.; Dunne, W. M.; Sanderson, David J.

2018-03-01

Spatial arrangement is a fundamental characteristic of fracture arrays. The pattern of fault and opening-mode fracture positions in space defines structural heterogeneity and anisotropy in a rock volume, governs how faults and fractures affect fluid flow, and impacts our understanding of the initiation, propagation and interactions during the formation of fracture patterns. This special issue highlights recent progress with respect to characterizing and understanding the spatial arrangements of fault and fracture patterns, providing examples over a wide range of scales and structural settings. Five papers describe new methods and improvements of existing techniques to quantify spatial arrangement. One study unravels the time evolution of opening-mode fracture spatial arrangement, which are data needed to compare natural patterns with progressive fracture growth in kinematic and mechanical models. Three papers investigate the role of evolving diagenesis in localizing fractures by mechanical stratigraphy and nine discuss opening-mode fracture spatial arrangement. Two papers show the relevance of complex cluster patterns to unconventional reservoirs through examples of fractures in tight gas sandstone horizontal wells, and a study of fracture arrangement in shale. Four papers demonstrate the roles of folds in fracture localization and the development spatial patterns. One paper models along-fault friction and fluid pressure and their effects on fault-related fracture arrangement. Contributions address deformation band patterns in carbonate rocks and fault size and arrangement above a detachment fault. Three papers describe fault and fracture arrangements in basement terrains, and three document fracture patterns in shale. This collection of papers points toward improvement in field methods, continuing improvements in computer-based data analysis and creation of synthetic fracture patterns, and opportunities for further understanding fault and fracture attributes in

Electricity generation sectors under purchase obligation: support arrangement analysis

International Nuclear Information System (INIS)

2013-04-01

This report aims at assessing the operation of the support arrangement by which currently benefit some electricity production sectors in France (renewable energies, co-generation) with respect to the evolution of the energy mix within the frame of energy transition. Other support arrangements presently adopted in Europe are also addressed as lessons to be learned. Criteria are established for any support arrangement. The report presents the French and European context regarding such support arrangement with purchasing obligation, and addresses the future evolutions of the European Commission. It highlights challenges for the electric system and for the energy market (impact on investments, optimization of market operation), describes and assesses the French purchasing obligation arrangement, and describes and assesses other existing support arrangements

Study on Pole Arrangement of the CEDM Coils

International Nuclear Information System (INIS)

Park, Jin Seok; Lee, Myoung Goo; Kim, Hyun Min; Cho, Yeon Ho; Choi, Taek Sang

2013-01-01

The coil stack assembly is important for reliable operation of the CEDM, there have been efforts to improve the design by optimizing the design parameters such as dimensions and winding turns. However, magnetic forces of the CEDM can also change by different pole arrangement even if their design parameters are the same. Since the latch coil and lift coil are installed connected to each other, they produce magnetically coupled field when they are energized at the same time. This coupling field can affect the magnetic force of the CEDM significantly. In this paper, coil pole arrangement effects are studied. Electro-magnetic analysis is performed for the different pole arrangements of the CEDM coils to calculate the magnetic forces. Pole arrangement effects on magnetic forces were studied by static analysis of the CEDM magnetic field. Magnetic forces were calculated and compared for the two different pole arrangements of the coils. The results show that the magnetic poles of the lift coil and latch coil shall be arranged to have the same magnetic pole direction to achieve higher magnetic force

Biophysical Constraints Arising from Compositional Context in Synthetic Gene Networks.

Science.gov (United States)

Yeung, Enoch; Dy, Aaron J; Martin, Kyle B; Ng, Andrew H; Del Vecchio, Domitilla; Beck, James L; Collins, James J; Murray, Richard M

2017-07-26

Synthetic gene expression is highly sensitive to intragenic compositional context (promoter structure, spacing regions between promoter and coding sequences, and ribosome binding sites). However, much less is known about the effects of intergenic compositional context (spatial arrangement and orientation of entire genes on DNA) on expression levels in synthetic gene networks. We compare expression of induced genes arranged in convergent, divergent, or tandem orientations. Induction of convergent genes yielded up to 400% higher expression, greater ultrasensitivity, and dynamic range than divergent- or tandem-oriented genes. Orientation affects gene expression whether one or both genes are induced. We postulate that transcriptional interference in divergent and tandem genes, mediated by supercoiling, can explain differences in expression and validate this hypothesis through modeling and in vitro supercoiling relaxation experiments. Treatment with gyrase abrogated intergenic context effects, bringing expression levels within 30% of each other. We rebuilt the toggle switch with convergent genes, taking advantage of supercoiling effects to improve threshold detection and switch stability. Copyright © 2017 Elsevier Inc. All rights reserved.

Arrangement for formation perforating and fracturing

Energy Technology Data Exchange (ETDEWEB)

Belyaev, B M; Vitsenii, E M; Zheltov, Yu P; Nikolaev, S I

1962-03-06

An arrangement for perforating and hydraulic fracturing, to be lowered on a wire line, consists of a chamber with a shaped charge, a head and a nozzle. This arrangement enables carrying out, simultaneously, the operations of perforating and fracturing. The device may be equipped with separate sections with shaped charges and a powder chamber in which powder charges are placed, designed to be ignited in sequence by slow- acting electric igniters. For controlling the gas pressure and strengthening the arrangement in the zone of perforation, the device is equipped with rubber seals which release the ring elements under pressure of explosive gas. Between the walls of the casing and the rubber seals is an annular space through the gas escapes.

Positioning of chromosomes in human spermatozoa is determined by ordered centromere arrangement.

Directory of Open Access Journals (Sweden)

Olga S Mudrak

Full Text Available The intranuclear positioning of chromosomes (CHRs is a well-documented fact; however, mechanisms directing such ordering remain unclear. Unlike somatic cells, human spermatozoa contain distinct spatial markers and have asymmetric nuclei which make them a unique model for localizing CHR territories and matching peri-centromere domains. In this study, we established statistically preferential longitudinal and lateral positioning for eight CHRs. Both parameters demonstrated a correlation with the CHR gene densities but not with their sizes. Intranuclear non-random positioning of the CHRs was found to be driven by a specific linear order of centromeres physically interconnected in continuous arrays. In diploid spermatozoa, linear order of peri-centromeres was identical in two genome sets and essentially matched the arrangement established for haploid cells. We propose that the non-random longitudinal order of CHRs in human spermatozoa is generated during meiotic stages of spermatogenesis. The specific arrangement of sperm CHRs may serve as an epigenetic basis for differential transcription/replication and direct spatial CHR organization during early embryogenesis.

Effects of Magnetic Particles Entrance Arrange-ments on Mixing Efficiency of a Magnetic Bead Micromixer

Institute of Scientific and Technical Information of China (English)

Reza Kamali∗; Seyed Alireza Shekoohi; Alireza Binesh

2014-01-01

In this study, a computer code is developed to numerically investigate a magnetic bead micromixer under different conditions. The micromixer consists of a microchannel and numerous micro magnetic particles which enter the micromixer by fluid flows and are actuated by an alternating magnetic field normal to the main flow. An important feature of micromixer which is not considered before by researchers is the particle entrance arrangement into the micromixer. This parameter could effectively affect the micromixer efficiency. There are two general micro magnetic particle entrance arrangements in magnetic bead micromixers: determined position entrance and random position entrance. In the case of determined position entrances, micro magnetic particles enter the micromixer at specific positions of entrance cross section. However, in a random position entrance, particles enter the microchannel with no order. In this study mixing efficiencies of identical magnetic bead micromixers which only differ in particle entrance arrangement are numerically investigated and compared. The results reported in this paper illustrate that the prepared computer code can be one of the most powerful and beneficial tools for the magnetic bead micromixer performance analysis. In addition, the results show that some features of the magnetic bead micromixer are strongly affected by the entrance arrangement of the particles.

Concepts for institutional arrangements for the nuclear fuel cycle

International Nuclear Information System (INIS)

1979-01-01

The paper focuses on the role of institutional arrangements in developing a consensus in international nuclear cooperation. Institutional arrangements are defined as undertakings and activities by governments or private entities to facilitate the efficient and secure functioning of the nuclear fuel cycle. The first two sections of the paper explore the historical role of cooperative arrangements, suggest criteria for evaluating the usefulness of institutional arrangements, and review the status of the discussion of institutional arrangements in INFCE Working Groups as of December 1978. The final section of the paper, explores potential relationships between various institutional arrangements and suggests that certain areas such as, the standardization of nuclear practices, joint commercial and development undertakings, nuclear supply assurances, and the settlement of disputes may have broad application for several stages of the fuel cycle and merit further study

People management implications of virtual workplace arrangements

Directory of Open Access Journals (Sweden)

K. Ortlepp

2006-12-01

Full Text Available Purpose: The purpose of this paper is to investigate the factors that led to an organisation implementing a particular form of virtual workplace arrangement, namely, home-based work. The benefits and disadvantages associated with this form of work arrangement are explored from both the managers' and home-based employees' perspectives. Design/Methodology/Approach: Given the exploratory nature of the empirical study on which this paper is based, a qualitative research design was adopted so as to ensure that the data collection process was dynamic and probing in nature. Semi-structured in-depth interviews were therefore used as instruments for data collection. Findings: The research findings indicate that virtual work arrangements such as home-based work arrangements have advantages for both employers and employees. For instance, reduction of costs associated with office space and facilities, decrease in absenteeism rates, increased employee job satisfaction and improvements in employees' general quality of life. However, a number of negative experiences related to this form of virtual work arrangement are also evident, for example, feelings of isolation as well as stress related to the inability to have firm boundaries between work and family responsibilities. Implications: Based on the insights gained from the findings in the empirical study, a number of areas that need to be given specific attention when organisations are introducing virtual workplace arrangements of this nature are identified. Recommendations made in this article are important for human resource management specialists as well as core business policy makers considering different forms of organisational design. Originality/Value: Maximising the quality of production and service provided has become the prime objective in most organisations in the 21st century. Technology has made it possible for some jobs to be performed at any place at any time and has facilitated the

Living arrangements of young adults in Europe

NARCIS (Netherlands)

Schwanitz, Katrin; Mulder, Clara H.

2015-01-01

Comparative research suggests that there are great cross-national and cross-temporal differences in living arrangements of young adults aged 18-34 in Europe. In this paper, we examine young adults’ living arrangements (1) across several European countries and different national contexts, and (2) by

Exchange rate arrangements: From extreme to "normal"

Directory of Open Access Journals (Sweden)

Beker Emilija

2006-01-01

Full Text Available The paper studies theoretical and empirical location dispersion of exchange rate arrangements - rigid-intermediate-flexible regimes, in the context of extreme arrangements of a currency board, dollarization and monetary union moderate characteristics of intermediate arrangements (adjustable pegs crawling pegs and target zones and imperative-process "normalization" in the form of a managed or clean floating system. It is established that de iure and de facto classifications generate "fear of floating" and "fear of pegging". The "impossible trinity" under the conditions of capital liberalization and globalization creates a bipolar view or hypothesis of vanishing intermediate exchange rate regimes.

Patient positioning and supporting arrangement

International Nuclear Information System (INIS)

Heavens, M.; James, R.C.; Slinn, D.S.

1980-01-01

This patent specification describes an E.M.I. claim relating to a patient positioning and support arrangement for a computerised axial tomography system, the arrangement comprising a curved platter upon which the patient can be disposed, a table having a curved groove to accommodate the platter, and means for driving the platter slidably along the groove; the platter being formed of a substantially rigid platform shaped to conform to the groove, and a shroud, secured to the platter and disposed between the platter and the surface of the groove, so as to permit the platter to slide smoothly. (U.K.)

Support mechanism for a mirrored surface or other arrangement

Science.gov (United States)

Cutburth, Ronald W.

1987-01-01

An adjustment mechanism such as a three point spherical mount for adjustably supporting a planer mirror or other type of arrangement relative to a plane defined by a given pair of intersecting perpendicular axes is disclosed herein. This mechanism includes first means for fixedly supporting the mirror or other arrangement such that the latter is positionable within the plane defined by the given pair of intersecting perpendicular axes. This latter means and the mirror or other such arrangement are supported by second means for limited movement back and forth about either of the intersecting axes. Moreover, this second means supports the first means and the mirror or other arrangement such that the latter is not movable in any other way whereby the point on the mirror or other arrangement coinciding with the intersection of the given axes does not move or float, thereby making the ability to adjust the mirror or other such arrangement more precise and accurate.

Baffle-former arrangement for nuclear reactor vessel internals

International Nuclear Information System (INIS)

Machado, O.J.; Berringer, R.T.

1978-01-01

A baffle-former arrangement for the reactor vessel internals of a nuclear reactor is described. The arrangement includes positioning of formers at the same elevations as the fuel assembly grids, and positioning flow holes in the baffle plates directly beneath selected former grid elevations. The arrangement reduces detrimental cross flows, maintains proper core barrel and baffle temperatures, and alleviates the potential of overpressurization within the baffle-former assembly under assumed major accident conditions

46 CFR 108.525 - Survival craft number and arrangement.

Science.gov (United States)

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Survival craft number and arrangement. 108.525 Section... UNITS DESIGN AND EQUIPMENT Lifesaving Equipment § 108.525 Survival craft number and arrangement. (a... arrangement of survival craft: (1) Lifeboats with an aggregate capacity to accommodate the total number of...

Labour Arrangements in Cassava Production in Oyo State, Nigeria

Directory of Open Access Journals (Sweden)

Abila, N.

2012-01-01

Full Text Available The study examined the effects of labour arrangements on the profitability of cassava enterprises in Oyo North Area of Oyo State, Nigeria. A multi-stage sampling technique was adopted for data collection, while data were analysed using descriptive statistics and budgetary analysis. The results show that the prevalent labour arrangements for cassava enterprises are: a combination of Family, Hired and Contract labour (38.9%; Family-Hired labour (27.8%; Family-Contract labour (31.1%. The gross margin per hectares across labour arrangements are N279481.99 (all-labour, N286044.24 (family-hired, N216940.10 (familycontract, and N235000.00 (family only. The returns on a naira invested on variable costs across different labour arrangements for cassava enterprises are N2.04 (all-labour, N3.66 (family-hired, N2.37 (familycontract, and N2.61 (family only. This implies that a unit (N1 variable cost in the various labour arrangements of all-labour, family/hired, family/contract and family only in cassava production will yield a marginal return of N3.04, N3.66, N2.37 and N2.61 respectively. Family-hired labour arrangement yields higher marginal return per unit of manday and one naira spent than all other arrangements. The study recommends among others the application of laboursaving technologies and an optimum combination of various labour arrangements to reduce the cost of labour used in cassava production.

29 CFR 779.228 - Types of arrangements contemplated by exception.

Science.gov (United States)

2010-07-01

... Coverage Leased Departments, Franchise and Other Business Arrangements § 779.228 Types of arrangements... section 3(s) would not otherwise apply: (a) Any arrangement, whether by agreement, franchise or otherwise...

Nonbilayer Phospholipid Arrangements Are Toll-Like Receptor-2/6 and TLR-4 Agonists and Trigger Inflammation in a Mouse Model Resembling Human Lupus

Directory of Open Access Journals (Sweden)

Carlos Wong-Baeza

2015-01-01

Full Text Available Systemic lupus erythematosus is characterized by dysregulated activation of T and B cells and autoantibodies to nuclear antigens and, in some cases, lipid antigens. Liposomes with nonbilayer phospholipid arrangements induce a disease resembling human lupus in mice, including IgM and IgG antibodies against nonbilayer phospholipid arrangements. As the effect of these liposomes on the innate immune response is unknown and innate immune system activation is necessary for efficient antibody formation, we evaluated the effect of these liposomes on Toll-like receptor (TLR signaling, cytokine production, proinflammatory gene expression, and T, NKT, dendritic, and B cells. Liposomes induce TLR-4- and, to a lesser extent, TLR-2/TLR-6-dependent signaling in TLR-expressing human embryonic kidney (HEK cells and bone marrow-derived macrophages. Mice with the lupus-like disease had increased serum concentrations of proinflammatory cytokines, C3a and C5a; they also had more TLR-4-expressing splenocytes, a higher expression of genes associated with TRIF-dependent TLR-4-signaling and complement activation, and a lower expression of apoptosis-related genes, compared to healthy mice. The percentage of NKT and the percentage and activation of dendritic and B2 cells were also increased. Thus, TLR-4 and TLR-2/TLR-6 activation by nonbilayer phospholipid arrangements triggers an inflammatory response that could contribute to autoantibody production and the generation of a lupus-like disease in mice.

Exchange rate regimes and monetary arrangements

Directory of Open Access Journals (Sweden)

Ivan Ribnikar

2005-06-01

Full Text Available There is a close relationship between a country’s exchange rate regime and monetary arrangement and if we are to examine monetary arrangements then exchange rate regimes must first be analysed. Within the conventional and most widely used classification of exchange rate regimes into rigid and flexible or into polar regimes (hard peg and float on one side, and intermediate regimes on the other there, is a much greater variety among intermediate regimes. A more precise and, as will be seen, more useful classification of exchange rate regimes is the first topic of the paper. The second topic is how exchange rate regimes influence or determine monetary arrangements and monetary policy or monetary policy regimes: monetary autonomy versus monetary nonautonomy and discretion in monetary policy versus commitment in monetary policy. Both topics are important for countries on their path to the EU and the euro area

Port entry arrangements

International Nuclear Information System (INIS)

Chicken, J.C.; King, M.A.

1978-01-01

The objective of the paper is to describe the safety scheme port authorities should establish to deal with any contingency that may result from the visit of a nuclear powered ship. The safety scheme should be devised to cover both normal operation and any accident conditions that could arise while the ship is in port. The paper is divided into three parts. The three parts being: background information, general instructions, and emergency procedures. The background information will describe the nature of the hazards a port authority has to be prepared to deal with, and the philosophical basis for a berthing policy. In the part dealing with general instructions the objective of the safety scheme will be described. Also this part will describe the composition of the Port Safety Panel, allocation of responsibilities, passage and berthing arrangements, general safety precautions, records required, and rescue arrangements. In the part dealing with emergency procedures the role of: the Ship's Master, Harbour Authorities, Local Police, and local Health Services are discussed. As an Appendix to the paper a copy of the safety scheme that has been devised for visits of nuclear merchant ships to Southampton is given

Frequency Arrangement For 700 MHz Band

Directory of Open Access Journals (Sweden)

Ancans G.

2015-02-01

Full Text Available The 694-790 MHz (700 MHz band was allocated by the 2012 World Radiocommunication Conference (WRC-12 in ITU Region 1 (Europe included, to the mobile service on a co-primary basis with other services to which this band was allocated on the primary basis and identified for the International Mobile Telecommunications (IMT. At the same time, the countries of Region 1 will be able also to continue using these frequencies for their broadcasting services if necessary. This allocation will be effective immediately after 2015 World Radiocommunication Conference (WRC-15. In order to make the best possible use of this frequency band for mobile service, a worldwide harmonized frequency arrangement is to be prepared to allow for large economies of scale and international roaming as well as utilizing the available spectrum in the best possible way, minimizing possible interference between services, facilitating deployment and cross-border coordination. The authors analyze different possible frequency arrangements and conclude on the frequency arrangement most suitable for Europe.

Imaging arrangement and microscope

Science.gov (United States)

Pertsinidis, Alexandros; Chu, Steven

2015-12-15

An embodiment of the present invention is an imaging arrangement that includes imaging optics, a fiducial light source, and a control system. In operation, the imaging optics separate light into first and second tight by wavelength and project the first and second light onto first and second areas within first and second detector regions, respectively. The imaging optics separate fiducial light from the fiducial light source into first and second fiducial light and project the first and second fiducial light onto third and fourth areas within the first and second detector regions, respectively. The control system adjusts alignment of the imaging optics so that the first and second fiducial light projected onto the first and second detector regions maintain relatively constant positions within the first and second detector regions, respectively. Another embodiment of the present invention is a microscope that includes the imaging arrangement.

Spiral phyllotaxis underlies constrained variation in Anemone (Ranunculaceae) tepal arrangement.

Science.gov (United States)

Kitazawa, Miho S; Fujimoto, Koichi

2018-05-01

Stabilization and variation of floral structures are indispensable for plant reproduction and evolution; however, the developmental mechanism regulating their structural robustness is largely unknown. To investigate this mechanism, we examined positional arrangement (aestivation) of excessively produced perianth organs (tepals) of six- and seven-tepaled (lobed) flowers in six Anemone species (Ranunculaceae). We found that the tepal arrangement that occurred in nature varied intraspecifically between spiral and whorled arrangements. Moreover, among the studied species, variation was commonly limited to three types, including whorls, despite five geometrically possible arrangements in six-tepaled flowers and two types among six possibilities in seven-tepaled flowers. A spiral arrangement, on the other hand, was unique to five-tepaled flowers. A spiral phyllotaxis model with stochasticity on initiating excessive primordia accounted for these limited variations in arrangement in cases when the divergence angle between preexisting primordia was less than 144°. Moreover, interspecific differences in the frequency of the observed arrangements were explained by the change of model parameters that represent meristematic growth and differential organ growth. These findings suggest that the phyllotaxis parameters are responsible for not only intraspecific stability but interspecific difference of floral structure. Decreasing arrangements from six-tepaled to seven-tepaled Anemone flowers demonstrate that the stabilization occurs as development proceeds to increase the component (organ) number, in contrast from the intuition that the variation will be larger due to increasing number of possible states (arrangements).

Friendship Repertoires and Care Arrangement: A Praxeological Approach.

Science.gov (United States)

Hahmann, Julia

2017-01-01

Friends are important companions and serve as sources for diverse dimensions of social support, including elderly care. Rather than researching populations that have already established care arrangements including friends, the author seeks to understand relationship systems with a focus on the inner logic friendship to consequently describe and understand involved care arrangements, be it with family members or friends. To illustrate the diversity of friendship repertoires, qualitative interviews with older adult Germans are analyzed regarding cognitive concepts of friendships in contrast to familiar ties as well as social practices around relationship systems. While some repertoires successfully include chosen ties in their care arrangements, others not only focus on family, they do not wish to receive care from friends. The article's praxeological approach highlights the need to reflect habitual differences when thinking about elderly informal care arrangements. © The Author(s) 2016.

Cable support arrangements

International Nuclear Information System (INIS)

Pendleton, E.; Murray, A.

1983-01-01

A cable support arrangement extending from a refuelling level floor of a nuclear reactor to the inner shield of a double rotatable shield comprises a linearly extensible cable support and disciplining boom, reaching from the floor to the main shield, and a circumferentially extensible cable support and disciplining means running from the end of the boom to a fixed end on the inner shield. (author)

Ulysses arrangements in psychiatry: a matter of good care?

Science.gov (United States)

Gremmen, I; Widdershoven, G; Beekman, A; Zuijderhoudt, R; Sevenhuijsen, S

2008-02-01

This article concerns the issue of how an ethic of care perspective may contribute to both normative theory and mental health care policy discussions on so called Ulysses arrangements, a special type of advance directives in psychiatry. The debate on Ulysses arrangements has predominantly been waged in terms of autonomy conceived of as the right to non-intervention. On the basis of our empirical investigations into the experiences of persons directly involved with Ulysses arrangements, we argue that a care ethics perspective may broaden and deepen the debate on Ulysses arrangements, by introducing additional concepts, such as vulnerability, responsibility and mutuality, and by refining familiar concepts, such as autonomy.

Employment arrangement, job stress, and health-related quality of life.

Science.gov (United States)

Ray, Tapas K; Kenigsberg, Tat'Yana A; Pana-Cryan, Regina

2017-12-01

We aimed to understand the characteristics of U.S. workers in non-standard employment arrangements, and to assess associations between job stress and Health-related Quality of Life (HRQL) by employment arrangement. As employers struggle to stay in business under increasing economic pressures, they may rely more on non-standard employment arrangements, thereby increasing the pool of contingent workers. Worker exposure to job stress may vary by employment arrangement. Excessive exposure to stressors at work is considered to be a potential health hazard, and may adversely affect health and HRQL. We used the Quality of Worklife (QWL) module which supplemented the General Social Survey (GSS) in 2002, 2006, 2010, and 2014. GSS is a biannual, nationally representative cross-sectional survey of U.S. households that yields a representative sample of the civilian, non-institutionalized, English-speaking, U.S. adult population. The QWL module assesses an array of psychosocial working conditions and quality of work life topics among GSS respondents. We used pooled QWL responses from 2002 to 2014 by only those who reported being employed at the time of the survey. After adjusting for sampling probabilities, including subsampling for non-respondents and correcting for the number of adults in the household, 6005 respondents were included in our analyses. We grouped respondents according to their employment arrangement, including: (i) independent contractors (contractor), (ii) on call workers (on call), (iii) workers paid by a temporary agency (temporary), (iv) workers who work for a contractor (under contract), or (v) workers in standard employment arrangements (standard). Respondents were further grouped into those who were stressed and those who were not stressed at work. Descriptive population prevalence rates were calculated by employment arrangement for select demographic and organizational characteristics, psychosocial working conditions, work-family balance, and health and

Extensive gene rearrangements in the mitochondrial genomes of two egg parasitoids, Trichogramma japonicum and Trichogramma ostriniae (Hymenoptera: Chalcidoidea: Trichogrammatidae).

Science.gov (United States)

Chen, Long; Chen, Peng-Yan; Xue, Xiao-Feng; Hua, Hai-Qing; Li, Yuan-Xi; Zhang, Fan; Wei, Shu-Jun

2018-05-04

Animal mitochondrial genomes usually exhibit conserved gene arrangement across major lineages, while those in the Hymenoptera are known to possess frequent rearrangements, as are those of several other orders of insects. Here, we sequenced two complete mitochondrial genomes of Trichogramma japonicum and Trichogramma ostriniae (Hymenoptera: Chalcidoidea: Trichogrammatidae). In total, 37 mitochondrial genes were identified in both species. The same gene arrangement pattern was found in the two species, with extensive gene rearrangement compared with the ancestral insect mitochondrial genome. Most tRNA genes and all protein-coding genes were encoded on the minority strand. In total, 15 tRNA genes and seven protein-coding genes were rearranged. The rearrangements of cox1 and nad2 as well as most tRNA genes were novel. Phylogenetic analysis based on nucleotide sequences of protein-coding genes and on gene arrangement patterns produced identical topologies that support the relationship of (Agaonidae + Pteromalidae) + Trichogrammatidae in Chalcidoidea. CREx analysis revealed eight rearrangement operations occurred from presumed ancestral gene order of Chalcidoidea to form the derived gene order of Trichogramma. Our study shows that gene rearrangement information in Chalcidoidea can potentially contribute to the phylogeny of Chalcidoidea when more mitochondrial genome sequences are available.

Effects of array arrangements in nano-patterned thin film media

International Nuclear Information System (INIS)

El-Hilo, M.

2010-01-01

In this work, the effect of different arrays arrangements on the magnetic behaviour of patterned thin film media is simulated. The modeled films consist of 80x80 cobalt grains of uniform diameter (20 nm) distributed into two different array arrangement: hexagonal (triangular) or square arrays. In addition to that, for each array arrangement, two cases of anisotropy orientations, random and textured films are considered. For both array arrangements and media orientations, hysteresis loops at different array separation (d) were simulated. Predictions show that for closely packed films, the shearing effects on the magnetization loop are much larger for the square array arrangement than the hexagonal one. According to these predictions, the bit switching field distribution in interacting 2D systems is much narrower for the hexagonal array arrangement. This result could be very important for high-density magnetic recording where a narrow bit switching field distribution is required.

Optimal support arrangement of piping systems using genetic algorithm

International Nuclear Information System (INIS)

Chiba, T.; Okado, S.; Fujii, I.; Itami, K.

1996-01-01

The support arrangement is one of the important factors in the design of piping systems. Much time is required to decide the arrangement of the supports. The authors applied a genetic algorithm to find the optimum support arrangement for piping systems. Examples are provided to illustrate the effectiveness of the genetic algorithm. Good results are obtained when applying the genetic algorithm to the actual designing of the piping system

Relationship outcomes in Indian-American love-based and arranged marriages.

Science.gov (United States)

Regan, Pamela C; Lakhanpal, Saloni; Anguiano, Carlos

2012-06-01

The meaning and purpose of marriage, and the manner in which spouses are selected, varies across cultures. Although many cultures have a tradition of arranged marriage, researchers interested in marital dynamics generally have focused on love-based marriages. Consequently, there is little information on relational outcomes within arranged marriages. This study compared relationship outcomes in love-based and arranged marriages contracted in the U.S. A community sample of 58 Indian participants living in the U.S. (28 arranged marriages, 30 love-based marriages) completed measures of marital satisfaction, commitment, companionate love, and passionate love. Men reported greater amounts of commitment, passionate love, and companionate love than women. Unexpectedly, no differences were found between participants in arranged and love-based marriages; high ratings of love, satisfaction, and commitment were observed in both marriage types. The overall affective experiences of partners in arranged and love marriages appear to be similar, at least among Indian adults living in contemporary U.S. society.

European top managers’ support for work-life arrangements

NARCIS (Netherlands)

Been, Wike M.; van der Lippe, Tanja; den Dulk, Laura; Das Dores Horta Guerreiro, Maria; Kanjuo Mrčela, Aleksandra; Niemistö, Charlotta

2017-01-01

Top managers—defined as CEOs, CFOs and members of boards of directors—decide to what degree their organization offers employees work-life arrangements. This study focuses on the conditions under which they support such arrangements. A factorial survey of 202 top managers in five European countries

46 CFR 199.245 - Survival craft embarkation and launching arrangements.

Science.gov (United States)

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft embarkation and launching arrangements... Passenger Vessels § 199.245 Survival craft embarkation and launching arrangements. (a) Each davit-launched liferaft must be arranged to be rapidly boarded by its full complement of persons. (b) All survival craft...

Recurring part arrangements in shape collections

KAUST Repository

Zheng, Youyi; Cohen-Or, Daniel; Averkiou, Melinos; Mitra, Niloy J.

2014-01-01

Extracting semantically related parts across models remains challenging, especially without supervision. The common approach is to co-analyze a model collection, while assuming the existence of descriptive geometric features that can directly identify related parts. In the presence of large shape variations, common geometric features, however, are no longer sufficiently descriptive. In this paper, we explore an indirect top-down approach, where instead of part geometry, part arrangements extracted from each model are compared. The key observation is that while a direct comparison of part geometry can be ambiguous, part arrangements, being higher level structures, remain consistent, and hence can be used to discover latent commonalities among semantically related shapes. We show that our indirect analysis leads to the detection of recurring arrangements of parts, which are otherwise difficult to discover in a direct unsupervised setting. We evaluate our algorithm on ground truth datasets and report advantages over geometric similarity-based bottom-up co-segmentation algorithms. © 2014 The Author(s) Computer Graphics Forum © 2014 The Eurographics Association and John Wiley & Sons Ltd. Published by John Wiley & Sons Ltd.

Recurring part arrangements in shape collections

KAUST Repository

Zheng, Youyi

2014-05-01

Extracting semantically related parts across models remains challenging, especially without supervision. The common approach is to co-analyze a model collection, while assuming the existence of descriptive geometric features that can directly identify related parts. In the presence of large shape variations, common geometric features, however, are no longer sufficiently descriptive. In this paper, we explore an indirect top-down approach, where instead of part geometry, part arrangements extracted from each model are compared. The key observation is that while a direct comparison of part geometry can be ambiguous, part arrangements, being higher level structures, remain consistent, and hence can be used to discover latent commonalities among semantically related shapes. We show that our indirect analysis leads to the detection of recurring arrangements of parts, which are otherwise difficult to discover in a direct unsupervised setting. We evaluate our algorithm on ground truth datasets and report advantages over geometric similarity-based bottom-up co-segmentation algorithms. © 2014 The Author(s) Computer Graphics Forum © 2014 The Eurographics Association and John Wiley & Sons Ltd. Published by John Wiley & Sons Ltd.

29 CFR 794.117 - Effect of franchises and other arrangements.

Science.gov (United States)

2010-07-01

... 29 Labor 3 2010-07-01 2010-07-01 false Effect of franchises and other arrangements. 794.117... âindependently Owned and Controlled Local Enterpriseâ § 794.117 Effect of franchises and other arrangements. Whether a franchise or other contractual arrangement affects the status of the enterprise as “an...

Inspection of Emergency Arrangements

International Nuclear Information System (INIS)

2013-01-01

The Working Group on Inspection Practices (WGIP) was tasked by the NEA CNRA to examine and evaluate the extent to which emergency arrangements are inspected and to identify areas of importance for the development of good inspection practices. WGIP members shared their approaches to the inspection of emergency arrangements by the use of questionnaires, which were developed from the requirements set out in IAEA Safety Standards. Detailed responses to the questionnaires from WGIP member countries have been compiled and are presented in the appendix to this report. The following commendable practices have been drawn from the completed questionnaires and views provided by WGIP members: - RBs and their Inspectors have sufficient knowledge and information regarding operator's arrangements for the preparedness and response to nuclear emergencies, to enable authoritative advice to be given to the national coordinating authority, where necessary. - Inspectors check that the operator's response to a nuclear emergency is adequately integrated with relevant response organisations. - Inspectors pay attention to consider the integration of the operator's response to safety and security threats. - The efficiency of international relations is checked in depth during some exercises (e.g. early warning, assistance and technical information), especially for near-border facilities that could lead to an emergency response abroad. - RB inspection programmes consider the adequacy of arrangements for emergency preparedness and response to multi-unit accidents. - RBs assess the adequacy of arrangements to respond to accidents in other countries. - The RB's role is adequately documented and communicated to all agencies taking part in the response to a nuclear or radiological emergency. - Inspectors check that threat assessments for NPPs have been undertaken in accordance with national requirements and that up-to-date assessments have been used as the basis for developing emergency plans for

Arrangement of Renal Arteries in Guinea Pig.

Science.gov (United States)

Mazensky, David; Flesarova, Slavka

2017-03-01

The aim of this study was to describe origin, localization, and variations of renal arteries in guinea pig. The study was carried out on 26 adult guinea pigs. We prepared corrosion casts of the guinea pig arterial system. Batson's corrosion casting kit no. 17 was used as the casting medium. In 57.7% of specimens, a. renalis dextra was present as a single vessel with different level of its origin from aorta abdominalis. In 38.5% of specimens, two aa. renales dextrae were present with variable origin and arrangement. The presence of three aa. renales dextrae we found in one specimen. In 76.9% of specimens, a. renalis sinistra was present as a single vessel with different level of its origin from aorta abdominalis and variable arrangement. In 23.1% of specimens, we found two aa. renales sinistrae with variable origin and arrangement. The anatomical knowledge of the renal arteries, and its variations are of extreme importance for the surgeon that approaches the retroperitoneal region in several experiments, results of which are extrapolated in human. This is the first work dealing with the description of renal arteries arrangement in guinea pig. Anat Rec, 300:556-559, 2017. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

29 CFR 779.230 - Franchise and other arrangements.

Science.gov (United States)

2010-07-01

... 29 Labor 3 2010-07-01 2010-07-01 false Franchise and other arrangements. 779.230 Section 779.230... Coverage Leased Departments, Franchise and Other Business Arrangements § 779.230 Franchise and other.... The quotation in § 779.229 from the Senate Report shows that Congress recognized that some franchise...

People management implications of virtual workplace arrangements

OpenAIRE

K. Ortlepp; X. Hloma

2006-01-01

Purpose: The purpose of this paper is to investigate the factors that led to an organisation implementing a particular form of virtual workplace arrangement, namely, home-based work. The benefits and disadvantages associated with this form of work arrangement are explored from both the managers' and home-based employees' perspectives. Design/Methodology/Approach: Given the exploratory nature of the empirical study on which this paper is based, a qualitative research design was adopt...

Living Arrangements and Suicidal Ideation among the Korean Elderly

Science.gov (United States)

Kim, Jibum; Lee, Yun-Suk; Lee, Jinkook

2016-01-01

Objectives This study examines how living arrangements are associated with suicidal ideation for older adults in South Korea, which has the highest suicide rate among OECD countries, and a particularly high suicide rate for older persons. Methods Analyzing a sample of 5,795 women and 3,758 men aged 65 and older from a nationwide representative cross-sectional data set, we examined how many older adults think about suicide over a one-year period, why they think about suicide, and whether living arrangements are associated with suicidal ideation. Results About one out of twelve respondents in our sample reported suicidal ideation. While women and men did not differ in the prevalence of suicidal ideation, women attributed their suicidal feelings to health problems, while men attributed theirs to economic difficulties. Logistic regression results indicated that living arrangements are associated with suicidal ideation for men but not women. Older men living with a spouse were less likely to have suicidal ideation than older men with other living arrangements (i.e., living alone, living with children without spouse, living with spouse and others). Conclusions Our results highlight the importance of living arrangements to older men’s suicidal ideation. We discuss gender differences in the implications of living arrangements to suicidal ideation within the context of Confucian culture. PMID:26317145

BIRTHDAY CAKE ACTIVITY STRUCTURED ARRANGEMENT FOR HELPING CHILDREN DETERMINING QUANTITIES

Directory of Open Access Journals (Sweden)

Neni Mariana

2010-07-01

Full Text Available Few researches have been concerned about relation between children’s spatialthinking and number sense. Narrowing for this small research, we focused onone component of spatial thinking, that is structuring objects, and onecomponent of number senses, that is cardinality by determining quantities. Thisstudy focused on a design research that was conducted in Indonesia in which weinvestigated pre-school children’s (between 2 and 3.5 years old ability inmaking structured arrangement and their ability to determine the quantities bylooking at the arrangements. The result shows us that some of the children wereable to make such arrangement. However, the children found difficulties eitherto determine quantities from those arrangements or to compare some structuresto easily recognize number of objects.Keywords: structures, structured arrangement, cardinality DOI: http://dx.doi.org/10.22342/jme.1.1.790.53-70

Flexible time arrangements: relevance and impact of part-time work in Switzerland

OpenAIRE

Krone-Germann, Irenka

2010-01-01

In recent labour market history, one of the most striking features has been the increase of non-standard employment arrangements. These types of arrangements refer to atypical and alternative employment arrangements which are often called flexible staffing arrangements. The utilization of these flexible labour arrangements has been, however, the source of much controversy in the last twenty years but nowadays it is becoming more and more common in the OECD countries, more specifically in Swit...

Mitochondrial Genomes of Kinorhyncha: trnM Duplication and New Gene Orders within Animals.

Science.gov (United States)

Popova, Olga V; Mikhailov, Kirill V; Nikitin, Mikhail A; Logacheva, Maria D; Penin, Aleksey A; Muntyan, Maria S; Kedrova, Olga S; Petrov, Nikolai B; Panchin, Yuri V; Aleoshin, Vladimir V

2016-01-01

Many features of mitochondrial genomes of animals, such as patterns of gene arrangement, nucleotide content and substitution rate variation are extensively used in evolutionary and phylogenetic studies. Nearly 6,000 mitochondrial genomes of animals have already been sequenced, covering the majority of animal phyla. One of the groups that escaped mitogenome sequencing is phylum Kinorhyncha-an isolated taxon of microscopic worm-like ecdysozoans. The kinorhynchs are thought to be one of the early-branching lineages of Ecdysozoa, and their mitochondrial genomes may be important for resolving evolutionary relations between major animal taxa. Here we present the results of sequencing and analysis of mitochondrial genomes from two members of Kinorhyncha, Echinoderes svetlanae (Cyclorhagida) and Pycnophyes kielensis (Allomalorhagida). Their mitochondrial genomes are circular molecules approximately 15 Kbp in size. The kinorhynch mitochondrial gene sequences are highly divergent, which precludes accurate phylogenetic inference. The mitogenomes of both species encode a typical metazoan complement of 37 genes, which are all positioned on the major strand, but the gene order is distinct and unique among Ecdysozoa or animals as a whole. We predict four types of start codons for protein-coding genes in E. svetlanae and five in P. kielensis with a consensus DTD in single letter code. The mitochondrial genomes of E. svetlanae and P. kielensis encode duplicated methionine tRNA genes that display compensatory nucleotide substitutions. Two distant species of Kinorhyncha demonstrate similar patterns of gene arrangements in their mitogenomes. Both genomes have duplicated methionine tRNA genes; the duplication predates the divergence of two species. The kinorhynchs share a few features pertaining to gene order that align them with Priapulida. Gene order analysis reveals that gene arrangement specific of Priapulida may be ancestral for Scalidophora, Ecdysozoa, and even Protostomia.

Mitochondrial Genomes of Kinorhyncha: trnM Duplication and New Gene Orders within Animals.

Directory of Open Access Journals (Sweden)

Olga V Popova

Full Text Available Many features of mitochondrial genomes of animals, such as patterns of gene arrangement, nucleotide content and substitution rate variation are extensively used in evolutionary and phylogenetic studies. Nearly 6,000 mitochondrial genomes of animals have already been sequenced, covering the majority of animal phyla. One of the groups that escaped mitogenome sequencing is phylum Kinorhyncha-an isolated taxon of microscopic worm-like ecdysozoans. The kinorhynchs are thought to be one of the early-branching lineages of Ecdysozoa, and their mitochondrial genomes may be important for resolving evolutionary relations between major animal taxa. Here we present the results of sequencing and analysis of mitochondrial genomes from two members of Kinorhyncha, Echinoderes svetlanae (Cyclorhagida and Pycnophyes kielensis (Allomalorhagida. Their mitochondrial genomes are circular molecules approximately 15 Kbp in size. The kinorhynch mitochondrial gene sequences are highly divergent, which precludes accurate phylogenetic inference. The mitogenomes of both species encode a typical metazoan complement of 37 genes, which are all positioned on the major strand, but the gene order is distinct and unique among Ecdysozoa or animals as a whole. We predict four types of start codons for protein-coding genes in E. svetlanae and five in P. kielensis with a consensus DTD in single letter code. The mitochondrial genomes of E. svetlanae and P. kielensis encode duplicated methionine tRNA genes that display compensatory nucleotide substitutions. Two distant species of Kinorhyncha demonstrate similar patterns of gene arrangements in their mitogenomes. Both genomes have duplicated methionine tRNA genes; the duplication predates the divergence of two species. The kinorhynchs share a few features pertaining to gene order that align them with Priapulida. Gene order analysis reveals that gene arrangement specific of Priapulida may be ancestral for Scalidophora, Ecdysozoa, and even

Employment arrangement, job stress, and health-related quality of life ☆

Science.gov (United States)

Ray, Tapas K.; Kenigsberg, Tat’Yana A.; Pana-Cryan, Regina

2017-01-01

Objective We aimed to understand the characteristics of U.S. workers in non-standard employment arrangements, and to assess associations between job stress and Health-related Quality of Life (HRQL) by employment arrangement. Background As employers struggle to stay in business under increasing economic pressures, they may rely more on non-standard employment arrangements, thereby increasing the pool of contingent workers. Worker exposure to job stress may vary by employment arrangement. Excessive exposure to stressors at work is considered to be a potential health hazard, and may adversely affect health and HRQL. Methods We used the Quality of Worklife (QWL) module which supplemented the General Social Survey (GSS) in 2002, 2006, 2010, and 2014. GSS is a biannual, nationally representative cross-sectional survey of U.S. households that yields a representative sample of the civilian, non-institutionalized, English-speaking, U.S. adult population. The QWL module assesses an array of psychosocial working conditions and quality of work life topics among GSS respondents. We used pooled QWL responses from 2002 to 2014 by only those who reported being employed at the time of the survey. After adjusting for sampling probabilities, including subsampling for non-respondents and correcting for the number of adults in the household, 6005 respondents were included in our analyses. We grouped respondents according to their employment arrangement, including: (i) independent contractors (contractor), (ii) on call workers (on call), (iii) workers paid by a temporary agency (temporary), (iv) workers who work for a contractor (under contract), or (v) workers in standard employment arrangements (standard). Respondents were further grouped into those who were stressed and those who were not stressed at work. Descriptive population prevalence rates were calculated by employment arrangement for select demographic and organizational characteristics, psychosocial working conditions, work

The making of local hospital discharge arrangements

DEFF Research Database (Denmark)

Burau, Viola; Bro, Flemming

2015-01-01

Background Timely discharge is a key component of contemporary hospital governance and raises questions about how to move to more explicit discharge arrangements. Although associated organisational changes closely intersect with professional interests, there are relatively few studies in the lite......Background Timely discharge is a key component of contemporary hospital governance and raises questions about how to move to more explicit discharge arrangements. Although associated organisational changes closely intersect with professional interests, there are relatively few studies...... in the literature on hospital discharge that explicitly examine the role of professional groups. Recent contributions to the literature on organisational studies of the professions help to specify how professional groups in hospitals contribute to the introduction and routinisation of discharge arrangements...... for patients with prostate cancer in two hospitals in Denmark. This represents a typical case that involves changes in professional practice without being first and foremost a professional project. The multiple case design also makes the findings more robust. The analysis draws from 12 focus groups...

46 CFR 199.220 - Survival craft and rescue boat embarkation arrangements.

Science.gov (United States)

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft and rescue boat embarkation arrangements... APPLIANCES AND ARRANGEMENTS LIFESAVING SYSTEMS FOR CERTAIN INSPECTED VESSELS Additional Requirements for Passenger Vessels § 199.220 Survival craft and rescue boat embarkation arrangements. (a) Survival craft...

46 CFR 167.15-28 - Inspection of lifesaving appliances and arrangements.

Science.gov (United States)

2010-10-01

... SCHOOLS PUBLIC NAUTICAL SCHOOL SHIPS Inspections § 167.15-28 Inspection of lifesaving appliances and arrangements. The inspection of lifesaving appliances and arrangements must be in accordance with the... 46 Shipping 7 2010-10-01 2010-10-01 false Inspection of lifesaving appliances and arrangements...

Arrangement for guiding transport cables

International Nuclear Information System (INIS)

1981-01-01

This patent relates especially to x-ray equipment such as that used for computerized tomography, and in particular to an arrangement for guiding and supporting a plurality of power transmission cables and cooling hoses in a flexible manner. (U.K.)

Special Issue: Flexible Work Arrangements.

Science.gov (United States)

Olmstead, Barney, Ed.

1996-01-01

Section 1 contains five chapters on flexible work arrangements, self-employment, working from home, part-time professionals, job sharing, and temporary employment. Section 2 includes reviews of four books on working flexibly, concluding with a list of 23 additional readings. (SK)

On capital allocation for stochastic arrangement increasing actuarial risks

Directory of Open Access Journals (Sweden)

Pan Xiaoqing

2017-01-01

Full Text Available This paper studies the increasing convex ordering of the optimal discounted capital allocations for stochastic arrangement increasing risks with stochastic arrangement decreasing occurrence times. The application to optimal allocation of policy limits is presented as an illustration as well.

Transcription of the soybean leghemoglobin genes during nodule development

DEFF Research Database (Denmark)

Marcker, Anne; Ø Jensen, Erik; Marcker, Kjeld A

1984-01-01

During the early stages of soybean nodule development the leghemoglobin (Lb) genes are activated sequentially in the opposite order to which they are arranged in the soybean genome. At a specific stage after the initial activation of all the Lb genes, a large increment occurs in the transcription...... of the Lb(c1), Lb(c3) and Lb(a) genes while the transcription of the Lb(c2) gene is not amplified to a similar extent. All the Lb genes retain significant activity for a long period during the lifetime of a nodule. Consequently the soybean Lb genes are not regulated by a developmental gene switching...

41 CFR 301-50.2 - How must I arrange my travel?

Science.gov (United States)

2010-07-01

... travel? 301-50.2 Section 301-50.2 Public Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL ALLOWANCES ARRANGING FOR TRAVEL SERVICES, PAYING TRAVEL EXPENSES, AND CLAIMING REIMBURSEMENT 50-ARRANGING FOR TRAVEL SERVICES § 301-50.2 How must I arrange my travel? You must...

46 CFR 31.36-1 - Lifesaving appliances and arrangements-TB/ALL.

Science.gov (United States)

2010-10-01

... 46 Shipping 1 2010-10-01 2010-10-01 false Lifesaving appliances and arrangements-TB/ALL. 31.36-1... CERTIFICATION Lifesaving Appliances and Arrangements § 31.36-1 Lifesaving appliances and arrangements—TB/ALL. All lifesaving appliances and arrangements on tank vessels must be in accordance with subchapter W...

Living arrangements and suicidal ideation among the Korean older adults.

Science.gov (United States)

Kim, Jibum; Lee, Yun-Suk; Lee, Jinkook

2016-12-01

This study examines how living arrangements are associated with suicidal ideation for older adults in South Korea, which has the highest suicide rate among OECD countries, and a particularly high suicide rate for older persons. Analyzing a sample of 5795 women and 3758 men aged 65 and older from a nationwide representative cross-sectional data-set, we examined how many older adults think about suicide over a one-year period, why they think about suicide, and whether living arrangements are associated with suicidal ideation. About 1 out of 12 respondents in our sample reported suicidal ideation. While women and men did not differ in the prevalence of suicidal ideation, women attributed their suicidal feelings to health problems, while men attributed theirs to economic difficulties. Logistic regression results indicated that living arrangements are associated with suicidal ideation for men but not women. Older men living with a spouse were less likely to have suicidal ideation than older men with other living arrangements (i.e., living alone, living with children without spouse, living with spouse, and others). Our results highlight the importance of living arrangements to older men's suicidal ideation. We discuss gender differences in the implications of living arrangements to suicidal ideation within the context of Confucian culture.

Military Technology and Conventional Weapons Export Controls: The Wassenaar Arrangement

National Research Council Canada - National Science Library

Grimmett, Richard F

2006-01-01

This report provides background on the Wassenaar Arrangement, which was formally established in July 1996 as a multilateral arrangement aimed at controlling exports of conventional weapons and related...

26 CFR 1.1402(a)-18 - Split-dollar life insurance arrangements.

Science.gov (United States)

2010-04-01

... life insurance arrangements. See §§ 1.61-22 and 1.7872-15 for rules relating to the treatment of split-dollar life insurance arrangements. [T.D. 9092, 68 FR 54352, Sept. 17, 2003] ... 26 Internal Revenue 12 2010-04-01 2010-04-01 false Split-dollar life insurance arrangements. 1...

Core arrangement in BWR type reactors

International Nuclear Information System (INIS)

Asano, Masayuki.

1981-01-01

Purpose: To decrease the number of fuel assemblies whose locations are to be changed upon fuel exchange, as well as unify the power distribution in the core by arranging, in a chess board configuration, a plurality pattern of unit reactor lattices each containing fuel assemblies of different burnup degrees in orthogonal positions to each other. Constitution: A first pattern of unit reactor lattice is formed by disposing fuel assemblies of burnup degree 1 and fuel assemblies of burnup degree 3 at orthogonal positions to each other. A second pattern of unit reactor lattice is formed by disposing fuel assemblies of burnup degree 2 and fuel assemblies of burnup degree 1 at orthogonal positions to each other. The unit lattices each in such a dispositions are arranged in a chess board arrangement. Since, the fuel assemblies of the burnup degree 1 in the first pattern unit lattices proceed to the burnup degree 2 and the fuel assemblies of the burnup degree 2 in the second pattern unit lattices proceed to the burnup degree 3 up to the fuel exchange stage, fuel exchange and movement have only to be made, not for those fuel assemblies, but for another half of the fuel assemblies. (Kawakami, Y.)

METHOD FOR DETERMINING THE MAXIMUM ARRANGEMENT FACTOR OF FOOTWEAR PARTS

Directory of Open Access Journals (Sweden)

DRIŞCU Mariana

2014-05-01

Full Text Available By classic methodology, designing footwear is a very complex and laborious activity. That is because classic methodology requires many graphic executions using manual means, which consume a lot of the producer’s time. Moreover, the results of this classical methodology may contain many inaccuracies with the most unpleasant consequences for the footwear producer. Thus, the costumer that buys a footwear product by taking into consideration the characteristics written on the product (size, width can notice after a period that the product has flaws because of the inadequate design. In order to avoid this kind of situations, the strictest scientific criteria must be followed when one designs a footwear product. The decisive step in this way has been made some time ago, when, as a result of powerful technical development and massive implementation of electronical calculus systems and informatics, This paper presents a product software for determining all possible arrangements of a footwear product’s reference points, in order to automatically acquire the maximum arrangement factor. The user multiplies the pattern in order to find the economic arrangement for the reference points. In this purpose, the user must probe few arrangement variants, in the translation and rotate-translation system. The same process is used in establishing the arrangement factor for the two points of reference of the designed footwear product. After probing several variants of arrangement in the translation and rotation and translation systems, the maximum arrangement factors are chosen. This allows the user to estimate the material wastes.

Do Knowledge Arrangements Affect Student Reading Comprehension of Genetics?

Science.gov (United States)

Wu, Jen-Yi; Tung, Yu-Neng; Hwang, Bi-Chi; Lin, Chen-Yung; Che-Di, Lee; Chang, Yung-Ta

2014-01-01

Various sequences for teaching genetics have been proposed. Three seventh-grade biology textbooks in Taiwan share similar key knowledge assemblages but have different knowledge arrangements. To investigate the influence of knowledge arrangements on student understanding of genetics, we compared students' reading comprehension of the three texts…

29 CFR 780.126 - Contract arrangements for raising poultry.

Science.gov (United States)

2010-07-01

... 29 Labor 3 2010-07-01 2010-07-01 false Contract arrangements for raising poultry. 780.126 Section... General Scope of Agriculture Raising of Livestock, Bees, Fur-Bearing Animals, Or Poultry § 780.126 Contract arrangements for raising poultry. Feed dealers and processors sometimes enter into contractual...

Ulysses arrangements in psychiatry: a matter of good care?

NARCIS (Netherlands)

Gremmen, I.; Widdershoven, G.A.M.; Beekman, A.T.F.; Zuijderhoudt, R.H.; Sevenhuijsen, S.

2008-01-01

This article concerns the issue of how an ethic of care perspective may contribute to both normative theory and mental health care policy discussions on so called Ulysses arrangements, a special type of advance directives in psychiatry. The debate on Ulysses arrangements has predominantly been waged

Ulysses Arrangements in psychiatry: A matter of good care?

NARCIS (Netherlands)

Gremmen, C.C.M.; Widdershoven, G.G; Beekman, A; Zuijderhoudt, R.; Sevenhuijsen, S.

2008-01-01

This article concerns the issue of how an ethic of care perspective may contribute to both normative theory and mental health care policy discussions on so called Ulysses arrangements, a special type of advance directives in psychiatry. The debate on Ulysses arrangements has predominantly been waged

48 CFR 501.105-1 - Publication and code arrangement.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Publication and code arrangement. 501.105-1 Section 501.105-1 Federal Acquisition Regulations System GENERAL SERVICES... 501.105-1 Publication and code arrangement. The GSAR is published in the following sources: (a) Daily...

28 CFR 550.44 - Procedures for arranging drug counseling.

Science.gov (United States)

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Procedures for arranging drug counseling... MANAGEMENT DRUG PROGRAMS Drug Services (Urine Surveillance and Counseling for Sentenced Inmates in Contract CTCs) § 550.44 Procedures for arranging drug counseling. The contract center staff shall hold a program...

The new electricity trading arrangements: prospects for market development

International Nuclear Information System (INIS)

Anon

1999-09-01

This Briefing Paper from OXERA argues that the OFGEM proposals will not solve the fundamental market problems and might even make things worse. They focus too narrowly on the technical design of one small part of the market (the Balancing Mechanism and associated imbalance settlement process), without considering the market context and dynamics. OXERA argues that the central emphasis of the White Paper was misplaced: reform of the electricity trading arrangements, the basis of the government's strategy, will not solve the upstream and downstream market problems. The Briefing Paper includes analysis of: the structure and operation of the proposed new electricity trading arrangements; risk in the electricity wholesale market, and the responses of market participants; the interaction between the new trading arrangements and other energy market developments - in particular, vertical integration between generators and suppliers; energy supply competition, and wider government policy; the prospects for market development under the new electricity trading arrangements. (author)

Steam generator arrangement

International Nuclear Information System (INIS)

Ssinegurski, E.

1981-01-01

A steam flow path arrangement for covering the walls of the rear gas pass of a steam generator is disclosed. The entire flow passes down the sidewalls with a minor portion then passing up through the rear wall to a superheater inlet header at an intermediate elevation. The major portion of the flow passes up the front wall and through hanger tubes to a roof header. From there the major portion passes across the roof and down the rear wall to the superheater inlet header at the intermediate elevation

Financial Arrangements and Relationship Quality in Low-Income Couples

Science.gov (United States)

Addo, Fenaba R.; Sassler, Sharon

2010-01-01

This study explored the association between household financial arrangements and relationship quality using a representative sample of low-income couples with children. We detailed the banking arrangements couples utilize, assessed which factors relate to holding a joint account versus joint and separate, only separate, or no account, and analyzed…

48 CFR 3001.105-1 - Publication and code arrangement.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Publication and code arrangement. 3001.105-1 Section 3001.105-1 Federal Acquisition Regulations System DEPARTMENT OF HOMELAND... Purpose, Authority, Issuance 3001.105-1 Publication and code arrangement. (a) The HSAR is published in: (1...

One mum too few: maternal status in host surrogate motherhood arrangements.

Science.gov (United States)

Oultram, Stuart

2015-06-01

In a host surrogate motherhood arrangement, the surrogate agrees to be implanted with, and carry to term, an embryo created from the commissioning couple's gametes. When the surrogate child is born, it is the surrogate mother who, according to UK law, holds the legal status of mother. By contrast, the commissioning mother possesses no maternal status and she can only attain it once the surrogate agrees to the completion of the arrangement. One consequence of this is that, in the event that a host arrangement fails, the commissioning mother is left without maternal status. In this paper, I argue that this denial of maternal status misrepresents the commissioning mother's role in the host arrangement and her relationship with the surrogate child. Consequently, I suggest that commissioning mothers participating in host surrogacy arrangements ought to be granted the status of mother in the event that the arrangement fails. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Gender and Ethnic Variation in Arranged Marriages in a Chinese City

Science.gov (United States)

Zang, Xiaowei

2008-01-01

Using a data set (N = 1,600) collected in the city of Urumchi in 2005, this article examines ethnic differences in arranged marriages in urban China. Data analysis shows a rapid decline in parental arrangement for both Uyghur Muslims and Han Chinese in Urumchi. Han Chinese are less likely than Uyghur Muslims to report arranged marriages, with main…

Flexible Work Arrangements in ARL Libraries. SPEC Kit #180.

Science.gov (United States)

Zabel, Diane, Comp.; And Others

This report presents the results of a survey of Association of Research Libraries (ARL) members about the current climate and practices regarding flexible work arrangements. Data are reported on the availability of schedule flexibility, job exchange, part-time arrangements, and leaves, as well as information about faculty status, tenure,…

Condition monitoring of a rotor arrangement in particular a wind turbine

DEFF Research Database (Denmark)

2017-01-01

the rotor arrangement rotates, recording corresponding values of azimuth angle and edgewise and flap wise root bending moments for a plurality of rotations of rotor arrangement, transforming by use of e.g. a multi blade coordinate transformation, a Park's transformation or similar transformation......The present invention relates to a method of determining the condition of a device comprising a rotor arrangement. The rotor arrangement comprising a rotational shaft and a number rotor blades each connected at the root to the rotational shaft and extending radially from the rotational shaft....... Sensors are arranged to measure for each rotor blade corresponding values of one or more of the following parameters: azimuth angle (Φ) (or a parameter related to the azimuth angle), root bending moment(s) (q), such as the edgewise and/or flapwise root bending moments. The method comprises, while...

Birthday Cake Activity Structured Arrangement for Helping Children Determining Quantities

Directory of Open Access Journals (Sweden)

Neni Mariana

2010-07-01

Full Text Available Few researches have been concerned about relation between children’s spatial thinking and number sense. Narrowing for this small research, we focused on one component of spatial thinking, that is structuring objects, and one component of number senses, that is cardinality by determining quantities. This study focused on a design research that was conducted in Indonesia in which we investigated pre-school children’s (between 2 and 3.5 years old ability in making structured arrangement and their ability to determine the quantities by looking at the arrangements. The result shows us that some of the children were able to make such arrangement. However, the children found difficulties either to determine quantities from those arrangements or to compare some structures to easily recognize number of objects.

Institutional arrangements of Currency Boards - Comparative Macroeconomic Analysis

OpenAIRE

Lubomira Anastassova

1999-01-01

This paper is concentrated on the comparative macroeconomic analysis of the differences stemming from the extent to which the institutional framework of the currency board arrangement is implemented in the legal and regulatory systems in the different countries. The main objective of taking into consideration and examining the currency board institutional arrangements is to distinguish between the impact that currency board countries and countries with pegged exchange rate have on different m...

Teaching Determinants Using Rook Arrangements

Science.gov (United States)

Hendrickson, Anders O. F.

2018-01-01

Teaching determinants poses significant challenges to the instructor of a proof-based undergraduate linear algebra course. The standard definition by cofactor expansion is ugly, lacks symmetry, and is hard for students to use in proofs. We introduce a visual definition of the determinant that interprets permutations as arrangements of…

New arrangement for the air cleanup system to recover tritium

International Nuclear Information System (INIS)

Nishikawa, Masabumi; Takahashi, Kohsaku; Munakata, Kenzo; Fukada, Satoshi; Kotoh, Kenji; Takeishi, Toshiharu

1997-01-01

At present, the standard arrangement of the air cleanup system responsible for emergency tritium recovery from room air is a catalytic oxidation bed with a heater followed by an adsorption bed with a cooler. One disadvantage of this arrangement is that trouble with the heater or the cooler could result in a loss of capacity to recover tritium. Another disadvantage of the catalyst-adsorption-bed arrangement is that tritiated water must be recovered with a high decontamination factor after dilution with a large amount of water vapor in the working atmosphere. The performance of a new arrangement for the air cleanup system, which consists of a precious metal catalyst bed preceded by an adsorption bed without heating equipment, is discussed. According to calculations, most of the tritium released to the room air is recovered in the catalyst bed through oxidation, adsorption, and isotope exchange reaction when the new arrangement is applied. The adsorption bed placed before the catalyst bed dehumidifies the process gas to such a degree that the oxidation reaction of tritium in the catalyst bed is not hindered by water vapor. 15 refs., 6 figs., 6 tabs

Identification of a Transcriptionally Forward α Gene and Two υ Genes within the Pigeon (Columba livia) IgH Gene Locus.

Science.gov (United States)

Huang, Tian; Wang, Xifeng; Si, Run; Chi, Hao; Han, Binyue; Han, Haitang; Cao, Gengsheng; Zhao, Yaofeng

2018-06-01

Compared with mammals, the bird Ig genetic system relies on gene conversion to create an Ab repertoire, with inversion of the IgA-encoding gene and very few cases of Ig subclass diversification. Although gene conversion has been studied intensively, class-switch recombination, a mechanism by which the IgH C region is exchanged, has rarely been investigated in birds. In this study, based on the published genome of pigeon ( Columba livia ) and high-throughput transcriptome sequencing of immune-related tissues, we identified a transcriptionally forward α gene and found that the pigeon IgH gene locus is arranged as μ-α-υ1-υ2. In this article, we show that both DNA deletion and inversion may result from IgA and IgY class switching, and similar junction patterns were observed for both types of class-switch recombination. We also identified two subclasses of υ genes in pigeon, which share low sequence identity. Phylogenetic analysis suggests that divergence of the two pigeon υ genes occurred during the early stage of bird evolution. The data obtained in this study provide new insight into class-switch recombination and Ig gene evolution in birds. Copyright © 2018 by The American Association of Immunologists, Inc.

46 CFR 167.20-17 - Bilge pumps, bilge piping and sounding arrangements.

Science.gov (United States)

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Bilge pumps, bilge piping and sounding arrangements. 167... Ships § 167.20-17 Bilge pumps, bilge piping and sounding arrangements. The number, capacity, and arrangement of bilge pumps and bilge piping shall be in accordance with the requirements for cargo vessels...

X-ray tube arrangements

International Nuclear Information System (INIS)

Gillard, R.G.

1980-01-01

A technique for ensuring the rapid correction of both amplitude and offset errors in the deflectional movement of an electron beam along an X-ray emissive target is described. The movement is monitored at at least two positions during a sweep and differences, between the two movements and a desired movement, at these positions are combined in different proportions to produce a corrective servo signal. Such arrangements find application, for example, in computerised tomographic scanners. (author)

William Barlow and the Determination of Atomic Arrangement in Crystals.

Science.gov (United States)

Mauskopf, Seymour H

2015-04-01

William Barlow (1845-1934) was an important if unconventional scientist, known for having developed the 'closest-packing' atomic models of crystal structure. He resumed an early nineteenth-century tradition of utilizing crystallographical and chemical data to determine atomic arrangements in crystals. This essay recounts Barlow's career and scientific activity in three parts: (a) His place in the tradition of determining atomic arrangement in context of this earlier tradition and of contemporaneous developments of crystallography and chemistry, (b) his unconventional career, and (c) the 'success' of his program to determine atomic arrangements in crystals and its influence on the work of William Lawrence Bragg.

Flexible work arrangements and work-family conflict after childbirth.

Science.gov (United States)

Grice, Mira M; McGovern, Patricia M; Alexander, Bruce H

2008-10-01

Previous research has revealed that work-family conflict negatively influences women's health following childbirth. To examine if flexible work arrangements were associated with work-family conflict among women, 1 year after childbirth. Employed women, aged >or=18, were recruited while hospitalized for childbirth. Flexible work arrangements were measured at 6 months and work-family conflict was measured at 12 months. General linear models estimated the association between flexible work arrangements and work-family conflict. Of 1157 eligible participants, 522 were included in this analysis giving a 45% response rate. Compared to women who reported that taking time off was very hard, those who reported it was not too hard (beta = -0.80, SE = 0.36, P hours was associated with greater home spillover (beta = 0.46, SE = 0.18, P work home was associated with increased home spillover (beta = 0.35, SE = 0.14, P work hours and the ability to take work home were associated with increased home spillover to work. The ability to take time off was associated with decreased job spillover to home. Additional research is needed to examine the intentional and unintentional consequences of flexible work arrangements.

Functional Potential of Bacterial Communities using Gene Context Information

Directory of Open Access Journals (Sweden)

Anwesha Mohapatra

2017-12-01

Full Text Available Estimation of the functional potential of a bacterial genome can be determined by accurate annotation of its metabolic pathways. Existing homology based methods for pathway annotation fail to account for homologous genes that participate in multiple pathways, causing overestimation of gene copy number. Mere presence of constituent genes of a candidate pathway which are dispersed on a genome often results in incorrect annotation, thereby leading to erroneous gene abundance and pathway estimation. Clusters of evolutionarily conserved coregulated genes are characteristic features in bacterial genomes and their spatial arrangement in the genome is constrained by the pathway encoded by them. Thus, in order to improve the accuracy of pathway prediction, it is important to augment homology based annotation with gene organization information. In this communication, we present a methodology considering prioritization of gene context for improved pathway annotation. Extensive literature mining was performed to confirm conserved juxtaposed arrangement of gene components of various pathways. Our method was utilized to identify and analyse the functional potential of all available completely sequenced bacterial genomes. The accuracy of the predicted gene clusters and their importance in metabolic pathways will be demonstrated using a few case studies. One of such case study corresponds to butyrate production pathways in gut bacteria where it was observed that gut pathogens and commensals possess a distinct set of pathway components. In another example, we will demonstrate how our methodology improves the prediction accuracy of carbohydrate metabolic potential in human microbial communities. Applicability of our method for estimation of functional potential in bacterial communities present in diverse environments will also be illustrated.

Nuclear reactor core stabilizing arrangement

International Nuclear Information System (INIS)

Jabsen, F.S.

1976-01-01

A nuclear reactor core stabilizing arrangement is described wherein a plurality of actuators, disposed in a pattern laterally surrounding a group of elongated fuel assemblies, press against respective contiguous fuel assemblies on the periphery of the group to reduce the clearance between adjacent fuel assemblies thereby forming a more compacted, vibration resistant core structure. 7 claims, 4 drawing figures

Storage arrangements for nuclear fuel

International Nuclear Information System (INIS)

Ealing, C.J.

1985-01-01

A storage arrangement for nuclear fuel has a plurality of storage tubes connected by individual pipes to manifolds which are connected, in turn, to an exhaust system for maintaining the tubes at sub-atmospheric pressure, and means for producing a flow of a cooling fluid, such as air, over the exterior surfaces of the tubes. (author)

Flow control arrangements for centrifuges

International Nuclear Information System (INIS)

Alderton, G.W.; Davidge, P.C.

1983-01-01

In a centrifuge plant for the separation of uranium isotopes, when a centrifuge machine breaks down, light gas is produced. This gas can cause adjacent machines to break down, so propagating the fault. The present invention provides flow control arrangements in gas pipes to the centrifuge, whereby sudden egress of gas from a failed machine is inhibited. (author)

The relationship between work arrangements and work-family conflict.

Science.gov (United States)

Higgins, Christopher; Duxbury, Linda; Julien, Mark

2014-01-01

A review of the literature determined that our understanding of the efficacy of flexible work arrangements (FWA) in reducing work-family conflict remains inconclusive. To shed light on this issue by examining the relationship between work-to-family conflict, in which work interferes with family (WFC), family-to-work conflict, in which family interferes with work (FWC), and four work arrangements: the traditional 9-5 schedule, compressed work weeks (CWWs) flextime, and telework. Hypotheses were tested on a sample of 16,145 employees with dependent care responsibilities. MANCOVA analysis was used with work arrangement as the independent variable and work interferes with family (WFC) and family interferes with work (FWC) as dependent variables. Work demands, non-work demands, income, job type and gender were entered into the analysis as covariates. The more flexible work arrangements such as flextime and telework were associated with higher levels of WFC than were fixed 9-to 5 and CWW schedules. Employees who teleworked reported higher FWC than their counterparts working a traditional 9-to-5 schedule particularly when work demands were high. The removal of both temporal and physical boundaries separating work and family domains results in higher levels of work-family interference in both directions. The results from this study suggest that policy makers and practitioners who are interested in improving employee well-being can reduce work-family conflict, and by extension improve employee mental health, by focusing on the effective use of traditional and CWW schedules rather than by implementing flextime and telework arrangements.

The effects of different source arrangement on the irradiation efficacy

International Nuclear Information System (INIS)

Liu Hongyue; Shi Peixin; Lin Yin

1999-01-01

The effects of 8 different arrangements with 16 pencil sources on irradiation productivity were studied by using a self-designed computer program. The results showed that the fashion of decentralized arrangement had a higher irradiation productivity than that of centralized in a static and uniform field

46 CFR 199.110 - Survival craft muster and embarkation arrangements.

Science.gov (United States)

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft muster and embarkation arrangements. 199... § 199.110 Survival craft muster and embarkation arrangements. (a) Each muster station must have... emergency source of electrical power. (e) Each davit-launched and free-fall survival craft muster station...

46 CFR 199.280 - Survival craft embarkation and launching arrangements.

Science.gov (United States)

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft embarkation and launching arrangements... Cargo Vessels § 199.280 Survival craft embarkation and launching arrangements. (a) Each lifeboat must be.... (d) All survival craft required for abandonment by the total number of persons on board must be...

Six-strut arrangements for cartesian movements of mirrors

International Nuclear Information System (INIS)

Noll, T.; Zeschke, Th.; Reichardt, G.; Lammert, H.; Gudat, W.

2001-01-01

At BESSY a new six-strut arrangement for general small travel mirror adjustment mechanisms has been developed. This patented (Patent DE 10042802.5) arrangement allows very simple movements in all six linear and rotational degrees of freedom. The movements of the mirror are simply determined by moving either one drive, or up to three drives by the same amount. The first mirror adjustment systems of this design is successfully in operation since the start of BESSY II. Their performance and reliability is very satisfactory. This contribution will present the concepts

Alkane Biosynthesis Genes in Cyanobacteria and Their Transcriptional Organization

International Nuclear Information System (INIS)

Klähn, Stephan; Baumgartner, Desirée; Pfreundt, Ulrike; Voigt, Karsten; Schön, Verena; Steglich, Claudia; Hess, Wolfgang R.

2014-01-01

In cyanobacteria, alkanes are synthesized from a fatty acyl-ACP by two enzymes, acyl–acyl carrier protein reductase and aldehyde deformylating oxygenase. Despite the great interest in the exploitation for biofuel production, nothing is known about the transcriptional organization of their genes or the physiological function of alkane synthesis. The comparison of 115 microarray datasets indicates the relatively constitutive expression of aar and ado genes. The analysis of 181 available genomes showed that in 90% of the genomes both genes are present, likely indicating their physiological relevance. In 61% of them they cluster together with genes encoding acetyl-CoA carboxyl transferase and a short-chain dehydrogenase, strengthening the link to fatty acid metabolism and in 76% of the genomes they are located in tandem, suggesting constraints on the gene arrangement. However, contrary to the expectations for an operon, we found in Synechocystis sp. PCC 6803 specific promoters for the two genes, sll0208 (ado) and sll0209 (aar), which give rise to monocistronic transcripts. Moreover, the upstream located ado gene is driven by a proximal as well as a second, distal, promoter, from which a third transcript, the ~160 nt sRNA SyR9 is transcribed. Thus, the transcriptional organization of the alkane biosynthesis genes in Synechocystis sp. PCC 6803 is of substantial complexity. We verified all three promoters to function independently from each other and show a similar promoter arrangement also in the more distant Nodularia spumigena, Trichodesmium erythraeum, Anabaena sp. PCC 7120, Prochlorococcus MIT9313, and MED4. The presence of separate regulatory elements and the dominance of monocistronic mRNAs suggest the possible autonomous regulation of ado and aar. The complex transcriptional organization of the alkane synthesis gene cluster has possible metabolic implications and should be considered when manipulating the expression of these genes in cyanobacteria.

Alkane biosynthesis genes in cyanobacteria and their transcriptional organization

Directory of Open Access Journals (Sweden)

Stephan eKlähn

2014-07-01

Full Text Available In cyanobacteria, alkanes are synthesized from a fatty acyl-ACP by two enzymes, acyl-acyl carrier protein reductase (AAR and aldehyde deformylating oxygenase (ADO. Despite the great interest in the exploitation for biofuel production, nothing is known about the transcriptional organization of their genes or the physiological function of alkane synthesis. The comparison of 115 microarray datasets indicates the relatively constitutive expression of aar and ado genes. The analysis of 181 available genomes showed that in 90% of the genomes both genes are present, likely indicating their physiological relevance. In 61% of them they cluster together with genes encoding acetyl-CoA carboxyl transferase and a short chain dehydrogenase, strengthening the link to fatty acid metabolism and in 76% of the genomes they are located in tandem, suggesting constraints on the gene arrangement. However, contrary to the expectations for an operon, we found in Synechocystis sp. PCC 6803 specific promoters for the two genes, sll0208 (ado and sll0209 (aar, that give rise to monocistronic transcripts. Moreover, the upstream located ado gene is driven by a proximal as well as a second, distal, promoter, from which a third transcript, the ~160 nt sRNA SyR9 is transcribed. Thus, the transcriptional organization of the alkane biosynthesis genes in Synechocystis sp. PCC 6803 is of substantial complexity. We verified all three promoters to function independently from each other and show a similar promoter arrangement also in the more distant Nodularia spumigena, Trichodesmium erythraeum, Anabaena sp. PCC 7120, Prochlorococcus MIT9313 and MED4. The presence of separate regulatory elements and the dominance of monocistronic mRNAs suggest the possible autonomous regulation of ado and aar. The complex transcriptional organization of the alkane synthesis gene cluster has possible metabolic implications and should be considered when manipulating the expression of these genes in

Alkane Biosynthesis Genes in Cyanobacteria and Their Transcriptional Organization

Energy Technology Data Exchange (ETDEWEB)

Klähn, Stephan; Baumgartner, Desirée; Pfreundt, Ulrike; Voigt, Karsten; Schön, Verena; Steglich, Claudia; Hess, Wolfgang R., E-mail: wolfgang.hess@biologie.uni-freiburg.de [Genetics and Experimental Bioinformatics, Institute of Biology 3, Faculty of Biology, University of Freiburg, Freiburg (Germany)

2014-07-14

In cyanobacteria, alkanes are synthesized from a fatty acyl-ACP by two enzymes, acyl–acyl carrier protein reductase and aldehyde deformylating oxygenase. Despite the great interest in the exploitation for biofuel production, nothing is known about the transcriptional organization of their genes or the physiological function of alkane synthesis. The comparison of 115 microarray datasets indicates the relatively constitutive expression of aar and ado genes. The analysis of 181 available genomes showed that in 90% of the genomes both genes are present, likely indicating their physiological relevance. In 61% of them they cluster together with genes encoding acetyl-CoA carboxyl transferase and a short-chain dehydrogenase, strengthening the link to fatty acid metabolism and in 76% of the genomes they are located in tandem, suggesting constraints on the gene arrangement. However, contrary to the expectations for an operon, we found in Synechocystis sp. PCC 6803 specific promoters for the two genes, sll0208 (ado) and sll0209 (aar), which give rise to monocistronic transcripts. Moreover, the upstream located ado gene is driven by a proximal as well as a second, distal, promoter, from which a third transcript, the ~160 nt sRNA SyR9 is transcribed. Thus, the transcriptional organization of the alkane biosynthesis genes in Synechocystis sp. PCC 6803 is of substantial complexity. We verified all three promoters to function independently from each other and show a similar promoter arrangement also in the more distant Nodularia spumigena, Trichodesmium erythraeum, Anabaena sp. PCC 7120, Prochlorococcus MIT9313, and MED4. The presence of separate regulatory elements and the dominance of monocistronic mRNAs suggest the possible autonomous regulation of ado and aar. The complex transcriptional organization of the alkane synthesis gene cluster has possible metabolic implications and should be considered when manipulating the expression of these genes in cyanobacteria.

Living arrangements in Western Europe: does cultural origin matter?

OpenAIRE

Giuliano, Paola

2006-01-01

Why are there such large differences in living arrangements across Western European countries? Conventional economic analyses have not been successful in explaining differences in living arrangements and particularly the dramatic increase in the fraction of young adults living with their parents in Mediterranean Europe. This paper presents a cultural interpretation. I argue that the sexual revolution of the 1970s - by liberalizing parental attitudes - had a differential impact on living arran...

46 CFR 199.40 - Evaluation, testing and approval of lifesaving appliances and arrangements.

Science.gov (United States)

2010-10-01

... appliances and arrangements. 199.40 Section 199.40 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LIFESAVING APPLIANCES AND ARRANGEMENTS LIFESAVING SYSTEMS FOR CERTAIN INSPECTED VESSELS General § 199.40 Evaluation, testing and approval of lifesaving appliances and arrangements. (a) Each item of...

Do organizational and political-legal arrangements explain financial wrongdoing?

Science.gov (United States)

Prechel, Harland; Zheng, Lu

2016-12-01

The 2008 financial crisis was a systemic problem with deep-rooted structural causes that created opportunities to engage in financial malfeasance, a form of corporate wrongdoing. However, few quantitative studies exist on the effects of organizational and political-legal arrangements on financial malfeasance. In this paper, we examine the effects of organizational and political-legal arrangements that emerged in the 1990s in the FIRE sector (i.e., financial, insurance, and real estate) on financial malfeasance. Our historical contextualization demonstrates how changes in the political-legal arrangements facilitate the emergence of new corporate structures and opportunities for financial malfeasance. Our longitudinal quantitative analysis demonstrates that US FIRE sector corporations with a more complex organizational structure, larger size, lower dividend payment, and higher executive compensation are more prone to commit financial malfeasance. © London School of Economics and Political Science 2016.

29 CFR 779.232 - Franchise or other arrangements which create a larger enterprise.

Science.gov (United States)

2010-07-01

... 29 Labor 3 2010-07-01 2010-07-01 false Franchise or other arrangements which create a larger... Apply; Enterprise Coverage Leased Departments, Franchise and Other Business Arrangements § 779.232 Franchise or other arrangements which create a larger enterprise. (a) In other instances, franchise...

Power distribution arrangement

DEFF Research Database (Denmark)

2010-01-01

An arrangement and a method for distributing power supplied by a power source to two or more of loads (e.g., electrical vehicular systems) is disclosed, where a representation of the power taken by a particular one of the loads from the source is measured. The measured representation of the amount...... of power taken from the source by the particular one of the loads is compared to a threshold to provide an overload signal in the event the representation exceeds the threshold. Control signals dependant on the occurring of the overload signal are provided such that the control signal decreases the output...... power of the power circuit in case the overload signal occurs...

33 CFR 149.313 - How must survival craft be arranged?

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false How must survival craft be... Equipment Manned Deepwater Port Requirements § 149.313 How must survival craft be arranged? The operator must arrange survival craft so that they meet the requirements of 46 CFR 108.525 (a) and § 108.530 and...

Storage arrangement for nuclear reactor fuel assemblies

International Nuclear Information System (INIS)

Wade, E.E.

1977-01-01

Said invention is intended for providing an arrangement of spent fuel assembly storage inside which the space is efficiently used without accumulating a critical mass. The storage is provided for long fuel assemblies having along their longitudinal axis an active part containing the fuel and an inactive part empty of fuel. Said storage arrangement comprises a framework constituting some long-shaped cells designed so as each of them can receive a fuel assembly. Means of axial positioning of said assembly in a cell make it possible to support the fuel assemblies inside the framework according to a spacing ratio, along the cell axis, such as the active part of an assembly is adjacent to the inactive part of the adjacent assemblies [fr

Characterization of the neurohypophysial hormone gene loci in elephant shark and the Japanese lamprey: origin of the vertebrate neurohypophysial hormone genes

Directory of Open Access Journals (Sweden)

Brenner Sydney

2009-02-01

Full Text Available Abstract Background Vasopressin and oxytocin are mammalian neurohypophysial hormones with distinct functions. Vasopressin is involved mainly in osmoregulation and oxytocin is involved primarily in parturition and lactation. Jawed vertebrates contain at least one homolog each of vasopressin and oxytocin, whereas only a vasopressin-family hormone, vasotocin, has been identified in jawless vertebrates. The genes encoding vasopressin and oxytocin are closely linked tail-to-tail in eutherian mammals whereas their homologs in chicken, Xenopus and coelacanth (vasotocin and mesotocin are linked tail-to-head. In contrast, their pufferfish homologs, vasotocin and isotocin, are located on the same strand of DNA with isotocin located upstream of vasotocin and separated by five genes. These differences in the arrangement of the two genes in different bony vertebrate lineages raise questions about their origin and ancestral arrangement. To trace the origin of these genes, we have sequenced BAC clones from the neurohypophysial gene loci in a cartilaginous fish, the elephant shark (Callorhinchus milii, and in a jawless vertebrate, the Japanese lamprey (Lethenteron japonicum. We have also analyzed the neurohypophysial hormone gene locus in an invertebrate chordate, the amphioxus (Branchiostoma floridae. Results The elephant shark neurohypophysial hormone genes encode vasotocin and oxytocin, and are linked tail-to-head like their homologs in coelacanth and non-eutherian tetrapods. Besides the hypothalamus, the two genes are also expressed in the ovary. In addition, the vasotocin gene is expressed in the kidney, rectal gland and intestine. These expression profiles indicate a paracrine role for the two hormones. The lamprey locus contains a single neurohypophysial hormone gene, the vasotocin. The synteny of genes in the lamprey locus is conserved in elephant shark, coelacanth and tetrapods but disrupted in teleost fishes. The amphioxus locus encodes a single

The Implications of Flexible Staffing Arrangements for Job Stability

OpenAIRE

Houseman, Susan N.; Polivka, Anne E.

1999-01-01

In this paper, we examine the job stability of workers in a wide range of flexible staffing arrangements: agency temporary, direct-hire temporary, on-call, contract company, independent contractor, and regular part-time work. We draw upon two data sources in our analysis. The first is a nationwide survey of employers on their use of flexible staffing arrangements conducted by the Upjohn Institute for Employment Research. This survey provides evidence on why employers use various types of flex...

National arrangements for incidents involving radioactivity (NAIR) 1982/83

International Nuclear Information System (INIS)

Roberts, G.C.

1984-01-01

A summary is presented of the data on incidents notified under the National Arrangements for Incidents involving Radioactivity (NAIR), extending the data previously reported to include information for 1982/83. The categories of incidents discussed include transport, damaged sources or containers, undamaged sources, empty containers found and hoaxes or false alarms. It is concluded that the Arrangements continue to demonstrate their value in minimizing the alarm potentially inherent in even minor incidents involving radioactive materials. (U.K.)

Role of crystal arrangement on the mechanical performance of enamel.

Science.gov (United States)

An, Bingbing; Wang, Raorao; Zhang, Dongsheng

2012-10-01

The superior mechanical properties of enamel, such as excellent penetration and crack resistance, are believed to be related to the unique microscopic structure. In this study, the effects of hydroxyapatite (HAP) crystallite orientation on the mechanical behavior of enamel have been investigated through a series of multiscale numerical simulations. A micromechanical model, which considers the HAP crystal arrangement in enamel prisms, the hierarchical structure of HAP crystals and the inelastic mechanical behavior of protein, has been developed. Numerical simulations revealed that, under compressive loading, plastic deformation progression took place in enamel prisms, which is responsible for the experimentally observed post-yield strain hardening. By comparing the mechanical responses for the uniform and non-uniform arrangement of HAP crystals within enamel prisms, it was found that the stiffness for the two cases was identical, while much greater energy dissipation was observed in the enamel with the non-uniform arrangement. Based on these results, we propose an important mechanism whereby the non-uniform arrangement of crystals in enamel rods enhances energy dissipation while maintaining sufficient stiffness to promote fracture toughness, mitigation of fracture and resistance to penetration deformation. Further simulations indicated that the non-uniform arrangement of the HAP crystals is a key factor responsible for the unique mechanical behavior of enamel, while the change in the nanostructure of nanocomposites could dictate the Young's modulus and yield strength of the biocomposite. Copyright © 2012 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

Distribution and genetic variation of hymenolepidid cestodes in murid rodents on the Canary Islands (Spain).

Science.gov (United States)

Foronda, Pilar; López-González, Mercedes; Hernández, Mariano; Haukisalmi, Voitto; Feliu, Carlos

2011-09-26

In the Canary Islands there are no previous data about tapeworms (Cestoda) of rodents. In order to identify the hymenolepidid species present in these hosts, a survey of 1,017 murine (349 Rattus rattus, 13 Rattus norvegicus and 655 Mus musculus domesticus) was carried out in the whole Archipelago. Molecular studies based on nuclear ITS1 and mitochondrial COI loci were performed to confirm the identifications and to analyse the levels of genetic variation and differentiation. Three species of hymenolepidids were identified: Hymenolepis diminuta, Rodentolepis microstoma and Rodentolepis fraterna. Hymenolepis diminuta (in rats) and R. microstoma (in mice) showed a widespread distribution in the Archipelago, and R. fraterna was the least spread species, appearing only on five of the islands. The hymenolepidids found on Fuerteventura, Lanzarote and La Graciosa were restricted to one area. The COI network of H. diminuta showed that the haplotypes from Lanzarote and Fuerteventura are the most distant with respect to the other islands, but clearly related among them. Founder effects and biotic and abiotic factors could have played important role in the presence/absence of the hymenolepidid species in determined locations. The haplotypes from the eastern islands (Fuerteventura and Lanzarote) seem to have shared an ancestral haplotype very distant from the most frequent one that was found in the rest of the islands. Two colonization events or a single event with subsequent isolation and reduced gene flow between western-central and eastern islands, have taken place in the Archipelago. The three tapeworms detected are zoonotic species, and their presence among rodents from this Archipelago suggests a potential health risk to human via environmental contamination in high risk areas. However, the relatively low prevalence of infestations detected and the focal distribution of some of these species on certain islands reduce the general transmission risk to human.

Distribution and genetic variation of hymenolepidid cestodes in murid rodents on the Canary Islands (Spain

Directory of Open Access Journals (Sweden)

Feliu Carlos

2011-09-01

Full Text Available Abstract Background In the Canary Islands there are no previous data about tapeworms (Cestoda of rodents. In order to identify the hymenolepidid species present in these hosts, a survey of 1,017 murine (349 Rattus rattus, 13 Rattus norvegicus and 655 Mus musculus domesticus was carried out in the whole Archipelago. Molecular studies based on nuclear ITS1 and mitochondrial COI loci were performed to confirm the identifications and to analyse the levels of genetic variation and differentiation. Results Three species of hymenolepidids were identified: Hymenolepis diminuta, Rodentolepis microstoma and Rodentolepis fraterna. Hymenolepis diminuta (in rats and R. microstoma (in mice showed a widespread distribution in the Archipelago, and R. fraterna was the least spread species, appearing only on five of the islands. The hymenolepidids found on Fuerteventura, Lanzarote and La Graciosa were restricted to one area. The COI network of H. diminuta showed that the haplotypes from Lanzarote and Fuerteventura are the most distant with respect to the other islands, but clearly related among them. Conclusions Founder effects and biotic and abiotic factors could have played important role in the presence/absence of the hymenolepidid species in determined locations. The haplotypes from the eastern islands (Fuerteventura and Lanzarote seem to have shared an ancestral haplotype very distant from the most frequent one that was found in the rest of the islands. Two colonization events or a single event with subsequent isolation and reduced gene flow between western-central and eastern islands, have taken place in the Archipelago. The three tapeworms detected are zoonotic species, and their presence among rodents from this Archipelago suggests a potential health risk to human via environmental contamination in high risk areas. However, the relatively low prevalence of infestations detected and the focal distribution of some of these species on certain islands reduce

Kinematics modeling and experimentation of the multi-manipulator tooth-arrangement robot for full denture manufacturing.

Science.gov (United States)

Zhang, Yong-de; Jiang, Jin-gang; Liang, Ting; Hu, Wei-ping

2011-12-01

Artificial teeth are very complicated in shape, and not easy to be grasped and manipulated accurately by a single robot. The method of tooth-arrangement by multi-manipulator for complete denture manufacturing proposed in this paper. A novel complete denture manufacturing mechanism is designed based on multi-manipulator and dental arch generator. Kinematics model of the multi-manipulator tooth-arrangement robot is built by analytical method based on tooth-arrangement principle for full denture. Preliminary experiments on tooth-arrangement are performed using the multi-manipulator tooth-arrangement robot prototype system. The multi-manipulator tooth-arrangement robot prototype system can automatically design and manufacture a set of complete denture that is suitable for a patient according to the jaw arch parameters. The experimental results verified the validity of kinematics model of the multi-manipulator tooth-arrangement robot and the feasibility of the manufacture strategy of complete denture fulfilled by multi-manipulator tooth-arrangement robot.

Creating flexible work arrangements through idiosyncratic deals.

Science.gov (United States)

Hornung, Severin; Rousseau, Denise M; Glaser, Jürgen

2008-05-01

A survey of 887 employees in a German government agency assessed the antecedents and consequences of idiosyncratic arrangements individual workers negotiated with their supervisors. Work arrangements promoting the individualization of employment conditions, such as part-time work and telecommuting, were positively related to the negotiation of idiosyncratic deals ("i-deals"). Worker personal initiative also had a positive effect on i-deal negotiation. Two types of i-deals were studied: flexibility in hours of work and developmental opportunities. Flexibility i-deals were negatively related and developmental i-deals positively related to work-family conflict and working unpaid overtime. Developmental i-deals were also positively related to increased performance expectations and affective organizational commitment, while flexibility i-deals were unrelated to either. PsycINFO Database Record (c) 2008 APA, all rights reserved.

Concepts for institutional arrangements for the nuclear fuel cycle

International Nuclear Information System (INIS)

1979-02-01

These concepts deal with establishing a framework for the analysis of institutional arrangements, with institutional arrangements under consideration in the working groups on fuel and heavy water availability, enrichment availability, assurances of long-term supply, reprocessing-plutonium handling-recycling, fast breeder reactors, spent fuel management, waste management and disposal, and advanced reactor concepts. The standardization of nuclear practices, joint commercial and development undertakings, nuclear supply assurances, developing a consensus in international nuclear co-operation, and settlements of disputes are treated

46 CFR 199.160 - Rescue boat embarkation, launching and recovery arrangements.

Science.gov (United States)

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Rescue boat embarkation, launching and recovery...) LIFESAVING APPLIANCES AND ARRANGEMENTS LIFESAVING SYSTEMS FOR CERTAIN INSPECTED VESSELS Requirements for All Vessels § 199.160 Rescue boat embarkation, launching and recovery arrangements. (a) Each rescue boat must...

Access to flexible work arrangements, working-time fit and job satisfaction

NARCIS (Netherlands)

Possenriede, D.S.; Plantenga, J.

2011-01-01

This article analyses the effects of access to flexible work arrangements, namely flexi-time, telehomework and part-time work, on employees’ satisfaction with the fit between paid work and private life and their overall job satisfaction. Having access to flexible work arrangements gives employees

First year effects of induction arrangements on beginning teachers' psychological processes

NARCIS (Netherlands)

Helms-Lorenz, Michelle; Slof, Bert; van de Grift, Wim

2013-01-01

This study examined the (1) effects of a supportive program (i.e., induction arrangement) on beginning teachers' (BTs') psychological processes after a period of 1 year and (2) psychological paths of influence of the arrangement. Participants (56 Dutch secondary schools with 143 BTs) were randomly

45 CFR 63.4 - Cooperative arrangements.

Science.gov (United States)

2010-10-01

... another State, to apply for assistance. (b) A joint application made by two or more applicants for... activities performed by each of the joint applicants or may have a combined budget. If joint applications... authorizing separate amounts for each of the joint applicants. (c) In the case of each cooperative arrangement...

15 CFR 743.1 - Wassenaar Arrangement.

Science.gov (United States)

2010-01-01

... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Wassenaar Arrangement. 743.1 Section 743.1 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU... following: a. 30 elements or less; or b. Incorporating time delay-and-integration within the element and...

75 FR 346 - Proposed Subsequent Arrangement

Science.gov (United States)

2010-01-05

... Uses of Nuclear Energy. This subsequent arrangement concerns the retransfer of 28,409 kg of U.S.-origin... Fuels in Kanakawa-ken, Japan. The material, which is currently located at Cameco, Port Hope, Ontario, will be transferred to Global Nuclear Fuel, Kanakawa-ken, Japan to be fabricated into fuel pellets and...

Emergency response arrangements for the transport of radioactive materials

International Nuclear Information System (INIS)

Morgan-Warren, E.

2004-01-01

Response arrangements are required for the transport of radioactive materials, under both transport and health and safety legislation, to safeguard persons, property and the environment in the event of incidents and emergencies. Responsibilities fall on both government and industry: government is responsible for ensuring public safety and providing information and reassurance. This responsibility is discharged for each type of incident by a nominated ''lead department'', supported as appropriate by other government departments and agencies; for their part, operators are obliged to have arrangements in place for dealing with the practicalities of any reasonably foreseeable incident, including recovery and onward transport of a package, and any required clean-up or restoration of the environment. This paper outlines both the government and industry arrangements in Great Britain. The principles of response and intervention are discussed, together with the lead department concept, regulatory requirements, and the plans developed by the transport industry to ensure a nation-wide response capability

Emergency response arrangements for the transport of radioactive materials

Energy Technology Data Exchange (ETDEWEB)

Morgan-Warren, E. [Radioactive Materials Transport Div., Dept. for Transport, London (United Kingdom)

2004-07-01

Response arrangements are required for the transport of radioactive materials, under both transport and health and safety legislation, to safeguard persons, property and the environment in the event of incidents and emergencies. Responsibilities fall on both government and industry: government is responsible for ensuring public safety and providing information and reassurance. This responsibility is discharged for each type of incident by a nominated ''lead department'', supported as appropriate by other government departments and agencies; for their part, operators are obliged to have arrangements in place for dealing with the practicalities of any reasonably foreseeable incident, including recovery and onward transport of a package, and any required clean-up or restoration of the environment. This paper outlines both the government and industry arrangements in Great Britain. The principles of response and intervention are discussed, together with the lead department concept, regulatory requirements, and the plans developed by the transport industry to ensure a nation-wide response capability.

Improvements in or relating to radiation detection arrangements

International Nuclear Information System (INIS)

Davis, G.P.

1977-01-01

A radiation detection arrangement is described that that comprises a number of scintillator devices, and a single multi-channel photomultiplier tube. Light from the scintillator devices is incident on the photocathode through an entrance window in the tube and multiplier entrance separating means are provided whereby light from each of the devices is made to be incident upon the channel entrances of photomultiplier tube. Various geometrical forms for the scintillator devices are described. This arrangement avoids the use of large number of small photomultiplier tubes, which is expensive and gives rise to difficulties in stacking the tubes in closely spaced side-by-side relationship. (U.K.)

46 CFR 108.550 - Survival craft launching and recovery arrangements: General.

Science.gov (United States)

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Survival craft launching and recovery arrangements...-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Lifesaving Equipment § 108.550 Survival craft.... (c) Each survival craft must be arranged to clear each leg, column, footing, brace, mat, and each...

46 CFR 199.150 - Survival craft launching and recovery arrangements; general.

Science.gov (United States)

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft launching and recovery arrangements... Vessels § 199.150 Survival craft launching and recovery arrangements; general. (a)(1) Each launching...) Unless expressly provided otherwise in this part, each survival craft must be provided with a launching...

46 CFR 133.150 - Survival craft launching and recovery arrangements: General.

Science.gov (United States)

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Survival craft launching and recovery arrangements...) OFFSHORE SUPPLY VESSELS LIFESAVING SYSTEMS Requirements for All OSVs § 133.150 Survival craft launching and recovery arrangements: General. (a) All survival craft required for abandonment by the total number of...

A Set of Indicators to Compare Local Governance Arrangements on Homelessness

NARCIS (Netherlands)

Boesveldt, N.F.

2015-01-01

This article describes a method of comparing new governance arrangements on homelessness by studying three key features: policy, structure and management style. This is done by using a set of indicators that has been developed to measure variations in such arrangements. These indicators are based on

Evolution of homeobox genes.

Science.gov (United States)

Holland, Peter W H

2013-01-01

Many homeobox genes encode transcription factors with regulatory roles in animal and plant development. Homeobox genes are found in almost all eukaryotes, and have diversified into 11 gene classes and over 100 gene families in animal evolution, and 10 to 14 gene classes in plants. The largest group in animals is the ANTP class which includes the well-known Hox genes, plus other genes implicated in development including ParaHox (Cdx, Xlox, Gsx), Evx, Dlx, En, NK4, NK3, Msx, and Nanog. Genomic data suggest that the ANTP class diversified by extensive tandem duplication to generate a large array of genes, including an NK gene cluster and a hypothetical ProtoHox gene cluster that duplicated to generate Hox and ParaHox genes. Expression and functional data suggest that NK, Hox, and ParaHox gene clusters acquired distinct roles in patterning the mesoderm, nervous system, and gut. The PRD class is also diverse and includes Pax2/5/8, Pax3/7, Pax4/6, Gsc, Hesx, Otx, Otp, and Pitx genes. PRD genes are not generally arranged in ancient genomic clusters, although the Dux, Obox, and Rhox gene clusters arose in mammalian evolution as did several non-clustered PRD genes. Tandem duplication and genome duplication expanded the number of homeobox genes, possibly contributing to the evolution of developmental complexity, but homeobox gene loss must not be ignored. Evolutionary changes to homeobox gene expression have also been documented, including Hox gene expression patterns shifting in concert with segmental diversification in vertebrates and crustaceans, and deletion of a Pitx1 gene enhancer in pelvic-reduced sticklebacks. WIREs Dev Biol 2013, 2:31-45. doi: 10.1002/wdev.78 For further resources related to this article, please visit the WIREs website. The author declares that he has no conflicts of interest. Copyright © 2012 Wiley Periodicals, Inc.

Radiation detector arrangements and methods

International Nuclear Information System (INIS)

Jackson, J.

1989-01-01

The patent describes a radiation detector arrangement. It comprises at least one detector element in the form of a temperature-sensitive resistor whose electrical resistance changes in response to radiation incident on the detector element, the resistor having a high positive temperature coefficient of electrical resistance at a transition in its electrical conductance, circuit means for applying a voltage across the resistor during operation of the detector arrangement, and temperature-regulation means for regulating the temperature of the resistor so as to operate the resistor in the transition, characterised in that the temperature-regulation means comprises the resistor and the circuit means which passes sufficient current through the resistor by resistance heating to a position in the transition at which a further increase in its temperature in response to incident radiation reduces the resistance heating by reducing the current, thereby stabilizing the temperature of the resistor at the position. The positive temperature coefficient at the position being sufficiently high that the change in the resistance heating produced by a change in the temperature of the resistor at the position is larger than a change in power of the incident radiation required to produce that same change in temperature of the resistor in the absence of any change in resistance heating

77 FR 35366 - Proposed Subsequent Arrangement

Science.gov (United States)

2012-06-13

... arrangement concerns the retransfer of 6,672,212 g of U.S.-origin enriched uranium fuel fabrications scrap, containing 233,977 g of the isotope U-235 (less than five percent enrichment), from Nuclear Fuel Industries... material, which is currently located at Nuclear Fuels Industries, Ltd. in Japan, will be transferred to...

Innovative Nuclear Power Plant Building Arrangement in Consideration of Decommissioning

OpenAIRE

Won-Jun Choi; Myung-Sub Roh; Chang-Lak Kim

2017-01-01

A new concept termed the Innovative Nuclear Power Plant Building Arrangement (INBA) strategy is a new nuclear power plant building arrangement method which encompasses upfront consideration of more efficient decommissioning. Although existing decommissioning strategies such as immediate dismantling and differed dismantling has the advantage of either early site restoration or radioactive decommissioning waste reduction, the INBA strategy has the advantages of both strategies. In this research...

Consequences of Teen Parents' Child-Care Arrangements for Mothers and Children

Science.gov (United States)

Mollborn, Stefanie; Blalock, Casey

2012-01-01

Using the nationally representative Early Childhood Longitudinal Study, Birth Cohort (2001-2006; N [image omitted]7,900), the authors examined child-care arrangements among teen parents from birth through prekindergarten. Four latent classes of child care arrangements at 9, 24, and 52 months emerged: (a) "parental care," (b) "center…

78 FR 72072 - Proposed Subsequent Arrangement

Science.gov (United States)

2013-12-02

... g of U.S.-origin atomized low-enriched uranium-7wt. % molybdenum powder, containing 365.638 g in the..., which is located at and was prepared by KAERI, will be used for the irradiation test of full-size fuel... subsequent arrangement concerning the retransfer of nuclear material of United States origin will not be...

Institutional arrangements in the emerging biodiesel industry: Case studies from Minas Gerais—Brazil

International Nuclear Information System (INIS)

Watanabe, Kassia; Bijman, Jos; Slingerland, Maja

2012-01-01

Connecting (small) family farmers to the emerging biodiesel industry requires careful design of the institutional arrangements between the producers of oil crops and the processing companies. According to institutional economics theory, the design of effective and efficient arrangements depends on production and transaction characteristics, the institutional environment, and the organizational environment supporting the transaction between producers and the industry. This paper presents a comparative study on two cases in the feedstock-for-biodiesel industry in the state of Minas Gerais, Brazil. The two case studies represent the production and transaction system of soybeans (Glycine max L. Merrill) and castor beans (Ricinus communis L.). Important elements of effective and efficient institutional arrangements are farmer collective action, availability of technical and financial support, and farmer experience with particular crops. - Highlights: ► We study institutional arrangements for feedstock transactions between family farmers and the biodiesel industry. ► We focussed on soybean and castor bean production and transaction systems. ► Institutional arrangements are affected by product and production characteristics. ► They are also affected by collective actions organizations such as cooperatives. ► Soybean involves lower transaction costs and therefore more simple arrangement than castor bean.

The deep disposal repository - an alternative general arrangement

International Nuclear Information System (INIS)

Wolofsky, L.

1996-01-01

For the disposal of nuclear fuel waste in Canada the current proposal requires a repository at or below 500 m depth in Precambrian plutonic igneous rock in Ontario, consisting of numerous horizontal parallel tunnels arranged in one or more horizontal planes i.e. a room-and-pillar arrangement. The pillars are three times as wide as the tunnels, giving as extraction ratio of 25%. The tunnels are tentatively designed to be excavated by drill and blast, with a flat-arched roof, vertical side walls and a flat invert. The fuel containing canisters are to be surrounded by a low-permeability bentonite-based buffer in vertical holes drilled for the purpose in the invert

Self arrangements in occupational safety and health management

International Nuclear Information System (INIS)

Ismail Bahari

2002-01-01

The book is written with the awareness of safe work culture where success does not lie to compliance with the law only. Instead it is more of an excellent management based on the principle of self organization. Self arrangements in the management of occupational safety and health do not rest on the shoulders of the employer or the safety management and safety communities, but are committed together with the leadership of the employer. Self arrangements will be more meaningful and successful if those involved have knowledge about the philosophy and principles of why and how this management is done, and so the method can be practiced and eventually cultivated as a working system. (author)

Canister arrangement for storing radioactive waste

Science.gov (United States)

Lorenzo, D.K.; Van Cleve, J.E. Jr.

1980-04-23

The subject invention relates to a canister arrangement for jointly storing high level radioactive chemical waste and metallic waste resulting from the reprocessing of nuclear reactor fuel elements. A cylindrical steel canister is provided with an elongated centrally disposed billet of the metallic waste and the chemical waste in vitreous form is disposed in the annulus surrounding the billet.

75 FR 82005 - Proposed Subsequent Arrangement

Science.gov (United States)

2010-12-29

... arrangement concerns the retransfer of 29,887 kg of U.S.-origin natural uranium dioxide (88.00% U), 26,300 kg... Fuel Co. Ltd. in Yuson-Gu, Taejon, South Korea. The material, which is currently located at Cameco, will be transferred for fuel fabrication by Korea Nuclear Fuel Co. Ltd for final use in a civilian...

Hox gene cluster of the ascidian, Halocynthia roretzi, reveals multiple ancient steps of cluster disintegration during ascidian evolution.

Science.gov (United States)

Sekigami, Yuka; Kobayashi, Takuya; Omi, Ai; Nishitsuji, Koki; Ikuta, Tetsuro; Fujiyama, Asao; Satoh, Noriyuki; Saiga, Hidetoshi

2017-01-01

Hox gene clusters with at least 13 paralog group (PG) members are common in vertebrate genomes and in that of amphioxus. Ascidians, which belong to the subphylum Tunicata (Urochordata), are phylogenetically positioned between vertebrates and amphioxus, and traditionally divided into two groups: the Pleurogona and the Enterogona. An enterogonan ascidian, Ciona intestinalis ( Ci ), possesses nine Hox genes localized on two chromosomes; thus, the Hox gene cluster is disintegrated. We investigated the Hox gene cluster of a pleurogonan ascidian, Halocynthia roretzi ( Hr ) to investigate whether Hox gene cluster disintegration is common among ascidians, and if so, how such disintegration occurred during ascidian or tunicate evolution. Our phylogenetic analysis reveals that the Hr Hox gene complement comprises nine members, including one with a relatively divergent Hox homeodomain sequence. Eight of nine Hr Hox genes were orthologous to Ci-Hox1 , 2, 3, 4, 5, 10, 12 and 13. Following the phylogenetic classification into 13 PGs, we designated Hr Hox genes as Hox1, 2, 3, 4, 5, 10, 11/12/13.a , 11/12/13.b and HoxX . To address the chromosomal arrangement of the nine Hox genes, we performed two-color chromosomal fluorescent in situ hybridization, which revealed that the nine Hox genes are localized on a single chromosome in Hr , distinct from their arrangement in Ci . We further examined the order of the nine Hox genes on the chromosome by chromosome/scaffold walking. This analysis suggested a gene order of Hox1 , 11/12/13.b, 11/12/13.a, 10, 5, X, followed by either Hox4, 3, 2 or Hox2, 3, 4 on the chromosome. Based on the present results and those previously reported in Ci , we discuss the establishment of the Hox gene complement and disintegration of Hox gene clusters during the course of ascidian or tunicate evolution. The Hox gene cluster and the genome must have experienced extensive reorganization during the course of evolution from the ancestral tunicate to Hr and Ci

WESSELÉNYI DOMAIN OF JIBOU, A MODEL OF MULTISECULAR ARRANGEMENT

Directory of Open Access Journals (Sweden)

ROZALIA BENEDEK

2015-10-01

Full Text Available Wesselényi Domain of Jibou, a Model of Multisecular Arrangement. Nowadays the nobiliary domains arouse the interest of specialists from various field and tourists. The typical nobility constructions are attractive both by their residential function –including curias, castles and palaces in Transylvania – and by the economic function of annexes composed of: mills, barns, stables, riding houses etc. These domains functioned as command centres of territorial arrangements from Medieval Age, premodern and modern ages with implications on the economic and social progress of ages and administrative structures, but also subsequent development. Our study aims to make a presentation of the nobiliary domain Wesselényi in Jibou, aiming to the identification of functions and strategic arrangements for valorisation of the domain as irradiation models of welfare and multiple values, which became a multisecular standard by: emblematic characters, decisive actions carried out by these characters, in Transylvania, Hungary and the Habsburg Empire, to which the Principality of Transylvania belonged until the Great Union of 1918. The management of Jibou domain of Wesselényi family was carried out by various state institutions after the nationalization of 1945, stipulated by Law 187/1945, occasion of new arrangement and valorisation strategies which will also be presented.

Leaf arrangements are invalid in the taxonomy of orchid species

Directory of Open Access Journals (Sweden)

Anna Jakubska-Busse

2017-07-01

Full Text Available The selection and validation of proper distinguishing characters are of crucial importance in taxonomic revisions. The modern classifications of orchids utilize the molecular tools, but still the selection and identification of the material used in these studies is for the most part related to general species morphology. One of the vegetative characters quoted in orchid manuals is leaf arrangement. However, phyllotactic diversity and ontogenetic changeability have not been analysed in detail in reference to particular taxonomic groups. Therefore, we evaluated the usefulness of leaf arrangements in the taxonomy of the genus Epipactis Zinn, 1757. Typical leaf arrangements in shoots of this genus are described as distichous or spiral. However, in the course of field research and screening of herbarium materials, we indisputably disproved the presence of distichous phyllotaxis in the species Epipactis purpurata Sm. and confirmed the spiral Fibonacci pattern as the dominant leaf arrangement. In addition, detailed analyses revealed the presence of atypical decussate phyllotaxis in this species, as well as demonstrated the ontogenetic formation of pseudowhorls. These findings confirm ontogenetic variability and plasticity in E. purpurata. Our results are discussed in the context of their significance in delimitations of complex taxa within the genus Epipactis.

Dynamics of dielectric barrier discharges in different arrangements

International Nuclear Information System (INIS)

Gibalov, Valentin I; Pietsch, Gerhard J

2012-01-01

Based on experimental results, numerical investigations of dielectric barrier discharges (DBDs) have been performed in three basic configurations: in the volume, coplanar and surface discharge arrangements. It is shown that the DBD dynamics is the same in all arrangements and it is determined by the development of a few principal constituents, i.e. cathode- and anode-directed streamers, discharge channel, cathode layer and surface charges. It is found that the anode- and cathode-directed streamers appear with a highly conductive channel in between. The interaction of the streamers with conductive and dielectric surfaces determines the filamentary or homogeneous appearance of the discharge and its properties. The cathode-directed streamer is a self-sustaining phenomenon, which moves in a gas gap or along an electrode driven by a positive loop-back between photoemission and electron multiplication. The anode-directed streamer plays a subsidiary role. Depending on the kind of gas (electronegative or electropositive) and/or the degree of development of the cathode-directed streamer, the field strength in the conductive channels changes significantly. When the cathode-directed streamer touches the electrode surface, a cathode layer appears with parameters close to those of normal glow discharges. In volume discharge arrangements the movement of the streamers results in the appearance of Lichtenberg figures on dielectric surfaces. (paper)

Nonstandard Work, Substandard Jobs. Flexible Work Arrangements in the U.S.

Science.gov (United States)

Kalleberg, Arne L.; Rasell, Edith; Cassirer, Naomi; Reskin, Barbara F.; Hudson, Ken; Webster, David; Appelbaum, Eileen; Spalter-Roth, Roberta M.

Nonstandard work arrangements (independent contracting, working for a temporary help agency, contract or on-call work, day labor, self-employment, and regular part-time employment) are growing more common in the United States. In 1995, more than 29 percent of all jobs were in nonstandard work arrangements. A study of these jobs and the…

Seal and bearing arrangement for use in a nuclear reactor

International Nuclear Information System (INIS)

Kazan, J.M.; Ritz, W.C.; Sharbaugh, J.E.

1982-01-01

A combination seal and bearing arrangement for use in a nuclear reactor including a vessel and vessel cover is disclosed herein. The vessel cover itself includes at least one rotatable plug which serves to perform certain position related functions within the reactor vessel and the combination seal and bearing arrangement is provided for sealing the annular opening around the rotation plug while, at the same time, providing a bearing support for the latter

Unsteady Flow Interactions Between Pitching Wings In Schooling Arrangements

Science.gov (United States)

Kurt, Melike; Moored, Keith

2017-11-01

In nature, many fish aggregate into large groups or schools for protection against predators, for social interactions and to save energy during migrations. Regardless of their prime motivation, fish experience three-dimensional flow interactions amongst themselves that can improve or hamper swimming performance and give rise to fluid-mediated forces between individuals. To date, the unsteady, three-dimensional flow interactions among schooling fish remains relatively unexplored. In order to study these interactions, the caudal fins of two interacting fish are idealized as two finite span pitching wings arranged in mixtures of canonical in-line and side-by-side arrangements. The forces and moments acting on the wings in the streamwise and cross-stream directions are quantified as the arrangement and the phase delay between the wings is altered. Particle image velocimetry is employed to characterize the flow physics during high efficiency locomotion. Finally, the forces and flowfields of two-dimensional pitching wings are compared with three-dimensional wings to distinguish how three-dimensionality alters the flow interactions in schools of fish.

Package and Assisted Travel Arrangement

Directory of Open Access Journals (Sweden)

Ivan Tot

2015-01-01

Full Text Available In the ordinary legislative procedure before the European Parliament and the Council, there is a proposal of the European Commission for the adoption of a new directive that would bring the regulation of the contract on organized tours into line with current market development of organized trips. The proposal is intended to regulate the various combinations of travel services that are today offered to passengers, particularly online, which are identical or comparable to the travel services provided in a classic pre-arranged package. The subject of the paper are the provisions of the proposal of the directive which govern the field of application of the proposed directive, in particular the proposed changes regarding the concept of "package" contained in the European Commission proposal and amendments of the European Parliament, as well as the analysis of the proposed new concept of "assisted travel arrangements." The paper also critically refers to the method of targeted maximum harmonization as a proposed new intensity of the harmonization. The conclusion is that, despite the welcome updating of an outdated text of the directive on package travel which is line with the current market needs, the proposed text of the new directive is burdened with technical and complex definitions that could lead to significant difficulties in their transposition into the provisions of national law of the Member States.

Multiple independent insertions of 5S rRNA genes in the spliced-leader gene family of trypanosome species.

Science.gov (United States)

Beauparlant, Marc A; Drouin, Guy

2014-02-01

Analyses of the 5S rRNA genes found in the spliced-leader (SL) gene repeat units of numerous trypanosome species suggest that such linkages were not inherited from a common ancestor, but were the result of independent 5S rRNA gene insertions. In trypanosomes, 5S rRNA genes are found either in the tandemly repeated units coding for SL genes or in independent tandemly repeated units. Given that trypanosome species where 5S rRNA genes are within the tandemly repeated units coding for SL genes are phylogenetically related, one might hypothesize that this arrangement is the result of an ancestral insertion of 5S rRNA genes into the tandemly repeated SL gene family of trypanosomes. Here, we use the types of 5S rRNA genes found associated with SL genes, the flanking regions of the inserted 5S rRNA genes and the position of these insertions to show that most of the 5S rRNA genes found within SL gene repeat units of trypanosome species were not acquired from a common ancestor but are the results of independent insertions. These multiple 5S rRNA genes insertion events in trypanosomes are likely the result of frequent founder events in different hosts and/or geographical locations in species having short generation times.

'Women’s work penalty' in the access to flexible working arrangements across Europe

OpenAIRE

Chung, Heejung

2018-01-01

Do women and workers in female dominated workplaces have better access to flexible working arrangements? Given women’s roles in caregiving and due to the ‘flexibility stigma’ that may come with the use of flexible working arrangements, women and workers in female-dominated workplaces are expected to have greater access. However, flexible working arrangements are also used for performance enhancing purposes, hence, following the gendered rewards/organisation literature, men and workers in male...

27 CFR 8.23 - Third party arrangements.

Science.gov (United States)

2010-04-01

..., DEPARTMENT OF THE TREASURY LIQUORS EXCLUSIVE OUTLETS Prohibited Practices § 8.23 Third party arrangements. Industry member requirements, by agreement or otherwise, with non-retailers which result in a retailer being required to purchase the industry member's products are within the exclusive outlet provisions...

Editorial: Spatial arrangement of faults and opening-mode fractures

Science.gov (United States)

Laubach, Stephen E.; Lamarche, Juliette; Gauthier, Bertand D. M.; Dunne, William M.

2018-03-01

This issue of the Journal of Structural Geology titled Spatial arrangement of faults and opening-mode fractures explores a fundamental characteristic of fault and fracture arrays. The pattern of fault and opening-mode fracture positions in space defines structural heterogeneity and anisotropy in a rock volume, governs how faults and fractures affect fluid flow, and impacts our understanding of the initiation, propagation and interactions during the formation of fracture patterns. This special issue highlights recent progress with respect to characterizing and understanding the spatial arrangements of fault and fracture patterns, providing examples over a wide range of scales and structural settings.

Camshaft bearing arrangement

Energy Technology Data Exchange (ETDEWEB)

Aoi, K.; Ozawa, T.

1986-06-10

A bearing arrangement is described for the camshaft of an internal combustion engine or the like which camshaft is formed along its length in axial order with a first bearing surface, a first cam lobe, a second bearing surface, a second cam lobe, a third bearing surface, a third cam lobe and a fourth bearing surface, the improvement comprising first bearing means extending around substantially the full circumference of the first bearing surface and journaling the first bearing surface, second bearing means extending around substantially less than the circumference of the second bearing surface and journaling the second bearing surface, third bearing means extending around substantially less than the circumference of the third bearing surface and journaling the third bearing surface, and fourth bearing means extending around substantially the full circumference of the fourth bearing surface and journaling the first bearing surface.

Better to receive than to give? Interorganizational service arrangements and hospital performance.

Science.gov (United States)

Trinh, Hanh Q; Begun, James W; Luke, Roice D

2010-01-01

The literature points to possible efficiencies in local-hospital-system performance, but little is known about the internal dynamics that might contribute to this. Study of the service arrangements that nearby same-system hospitals have with one another should provide clues into how system efficiencies might be attained. The purpose of this research was to better understand the financial and operational effects of service sharing and receiving arrangements among nearby hospitals belonging to the same systems. Data are compiled for the 1,227 U.S. urban acute care hospitals that belong to multihospital systems. A longitudinal structural equation model is employed-environmental pressures and organizational characteristics in 1997 are associated with service sharing and receiving arrangements in 2000; service sharing and receiving arrangements are then associated with performance in 2003. Service sharing and receiving are measured by counts of services focal hospitals report that are not duplicated by other-system hospitals within the same county. Linear Structural Relations (LISREL) is used to estimate the model. In general, market competition from managed care and hospitals influences hospitals to exchange services. For individual hospitals, service sharing has no effects on operational efficiency and financial performance. Service receiving, however, is related to greater efficiencies and higher profits. The findings underscore the asymmetrical relationships that exist among local-system hospitals. Individual hospitals benefit from service receiving arrangements but not from sharing arrangements-it is better to receive than to give. To the extent that individual hospitals independently determine service capacities, systems may not be able to effectively rationalize service offerings.

Dancing together and separate again: gymnosperms exhibit frequent changes of fundamental 5S and 35S rRNA gene (rDNA) organisation.

Science.gov (United States)

Garcia, S; Kovařík, A

2013-07-01

In higher eukaryotes, the 5S rRNA genes occur in tandem units and are arranged either separately (S-type arrangement) or linked to other repeated genes, in most cases to rDNA locus encoding 18S-5.8S-26S genes (L-type arrangement). Here we used Southern blot hybridisation, PCR and sequencing approaches to analyse genomic organisation of rRNA genes in all large gymnosperm groups, including Coniferales, Ginkgoales, Gnetales and Cycadales. The data are provided for 27 species (21 genera). The 5S units linked to the 35S rDNA units occur in some but not all Gnetales, Coniferales and in Ginkgo (∼30% of the species analysed), while the remaining exhibit separate organisation. The linked 5S rRNA genes may occur as single-copy insertions or as short tandems embedded in the 26S-18S rDNA intergenic spacer (IGS). The 5S transcript may be encoded by the same (Ginkgo, Ephedra) or opposite (Podocarpus) DNA strand as the 18S-5.8S-26S genes. In addition, pseudogenised 5S copies were also found in some IGS types. Both L- and S-type units have been largely homogenised across the genomes. Phylogenetic relationships based on the comparison of 5S coding sequences suggest that the 5S genes independently inserted IGS at least three times in the course of gymnosperm evolution. Frequent transpositions and rearrangements of basic units indicate relatively relaxed selection pressures imposed on genomic organisation of 5S genes in plants.

A survey of UK fertility clinics' approach to surrogacy arrangements.

Science.gov (United States)

Norton, Wendy; Crawshaw, Marilyn; Hudson, Nicky; Culley, Lorraine; Law, Caroline

2015-09-01

This paper draws on the findings of the first survey of surrogacy arrangements in Human Fertilisation and Embryology Authority (HFEA) licensed fertility clinics since 1998. Given the complex social, ethical and legal issues involved, surrogacy continues to raise debate worldwide and fuel calls for increased domestic provision in developed countries. However, little is known about how recent changes have affected HFEA licensed clinics. A 24-item online survey was undertaken between August and October 2013, designed to improve understanding of recent trends and current practices associated with UK-based surrogacy, and consider the implications for future policy and practice in UK and cross-border surrogacy arrangements. The response rate was 51.4%, comprising 54 clinics. Quantitative data were analysed using descriptive statistics, and open-ended qualitative responses analysed for extending understanding. Of the participating clinics, 42.6% offered surrogacy (mostly gestational surrogacy). Heterosexual couples using gestational surrogacy were the largest group currently using services followed by male same-sex couples. Most clinics reported having encountered problems with surrogacy treatments, suggesting barriers still exist to expanding the UK provision of surrogacy arrangements. It is important that professionals are well informed about the legal implications of surrogacy and that clinics have consistent and appropriate operational protocols for surrogacy arrangements. Copyright © 2015 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

Metacognitive Scaffolding in an Innovative Learning Arrangement

Science.gov (United States)

Molenaar, Inge; van Boxtel, Carla A. M.; Sleegers, Peter J. C.

2011-01-01

This study examined the effects of metacognitive scaffolds on learning outcomes of collaborating students in an innovative learning arrangement. The triads were supported by computerized scaffolds, which were dynamically integrated into the learning process and took a structuring or problematizing form. In an experimental design the two…

Circuit arrangement for indicating radiation dose rates

International Nuclear Information System (INIS)

Virag, Ernoe; Nyari, Istvan; Simon, Jozsef; Styevko, Mihaly; Krampe, Geza.

1981-01-01

The invention presents a dosemeter electronic circuit arrangement indicating hazardous dose rate threshold. If the treshold is reached or exceeded, well distinguished sound and light alarm is turned on immidiately. Moreover, certain critical levels can also be indicated by making the intermittent singalling continuous. (A.L.)

41 CFR 105-1.109-51 - Arrangement.

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Arrangement. 105-1.109-51 Section 105-1.109-51 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION 1-INTRODUCTION 1.1-Regulations System § 105-1...

UK nuclear terrorism insurance arrangements: an overview

International Nuclear Information System (INIS)

Tetley, M. G.

2004-01-01

The risk of terrorism in the UK is not new, but since the New York World Trade Centre attacks in 2001, the potential scale of any terrorist attack has required a considerable reassessment. With UK foreign policy closely aligned to that of the USA, the UK security services now consider it is simply a matter of when and no longer if the UK is attacked. For insurers of any type this fact would cause concern; for insurers involved in high profile and potentially catastrophic loss targets such as nuclear power plants, any attack could have a severe impact on solvency and shareholder's funds. This paper's objective is to describe the terrorism insurance arrangements put in place in the U.K. both before and after the September 2001 attacks. These arrangements have been designed both to safeguard insurers' solvency and to ensure that the nuclear industry and general public can continue to be reassured by the availability of insurance should an attack ever occur.(author)

Lepromatous leprosy patients produce antibodies that recognise non-bilayer lipid arrangements containing mycolic acids

Directory of Open Access Journals (Sweden)

Isabel Baeza

2012-12-01

Full Text Available Non-bilayer phospholipid arrangements are three-dimensional structures that form when anionic phospholipids with an intermediate structure of the tubular hexagonal phase II are present in a bilayer of lipids. Antibodies that recognise these arrangements have been described in patients with antiphospholipid syndrome and/or systemic lupus erythematosus and in those with preeclampsia; these antibodies have also been documented in an experimental murine model of lupus, in which they are associated with immunopathology. Here, we demonstrate the presence of antibodies against non-bilayer phospholipid arrangements containing mycolic acids in the sera of lepromatous leprosy (LL patients, but not those of healthy volunteers. The presence of antibodies that recognise these non-bilayer lipid arrangements may contribute to the hypergammaglobulinaemia observed in LL patients. We also found IgM and IgG anti-cardiolipin antibodies in 77% of the patients. This positive correlation between the anti-mycolic-non-bilayer arrangements and anti-cardiolipin antibodies suggests that both types of antibodies are produced by a common mechanism, as was demonstrated in the experimental murine model of lupus, in which there was a correlation between the anti-non-bilayer phospholipid arrangements and anti-cardiolipin antibodies. Antibodies to non-bilayer lipid arrangements may represent a previously unrecognised pathogenic mechanism in LL and the detection of these antibodies may be a tool for the early diagnosis of LL patients.

New arrangements in climate policy

International Nuclear Information System (INIS)

Arts, B.J.M.

2000-01-01

Climate policy, its content and the way it is being organised, is changing, both nationally and internationally. The Kyoto Protocol and its effects form an important catalyst for this process. The focus in climate discourse is increasingly on 'differentiation' and 'flexibilisation', while the role of the industrial sectors involved has changed since 1997, among other things expressed in the increasing influence exerted by the business community and the declining power of the environmental movement. There is a transition underway, from pluralist to private policy arrangements

Patient sensing and indicating arrangement for a computed tomography system

International Nuclear Information System (INIS)

Barrett, D.M.

1979-01-01

An arrangement is provided for sensing and indicating if a cross section of a patient extends beyond an image reconstruction circle during examination. The arrangement is positioned within a generally vertical gantry having a generally cylindrical opening for receiving the patient. The arrangement includes a plurality of light emitting sources disposed within the gantry and which are closely adjacent the reconstruction circle. Each light emitting source projects a light beam along a line which is parallel with the plane of the reconstruction circle and tangent to a cylinder having a diameter and central axis in agreement with the reconstruction circle. The light beams extend substantially across the opening in the gantry and generally inscribe the reconstruction circle. A plurality of photodetectors are disposed within the gantry and aligned to receive each of the light beams. The photodetectors are interconnected to the system by means for indicating an interruption of any of the light beams between any of the sources and detectors

Agronomic performance of velvet bean at different spatial arrangement

International Nuclear Information System (INIS)

Silva, Aijanio Gomes de Brito; Goncalves Junior, Murilo; Guerra, Jose Guilherme Marinho; Costa, Janaina Ribeiro; Espindola, Jose Antonio Azevedo; Araujo, Ednaldo da Silva

2011-01-01

The objective of this work was to evaluate the effect of different plant spatial arrangements on agronomic performance of velvet-bean (Mucuna pruriens var. utilis). The experiment was performed with eight treatments, distributed in a randomized complete block design in a 2x4 factorial arrangement, with four replicates. The treatments were velvet bean sowing at two spacings between furrows (0.5 and 1.0 m) and four plant densities (2, 4, 8 and 16 plants m -1 ). Determinations were made for the soil covering and biological nitrogen fixation (BNF) rates, and for the dry matter yield and N accumulation in the plant shoots. Total soil cover was accomplished at 50 days after sowing at 16 plants m -1 density and 0.5 m spacing between furrows. The combination of 16 plants m -1 1density with the 1.0 m spacing between furrows provided the greatest dry matter yield and accumulated most N in the plant shoots. Irrespective of the plant spatial arrangement, the estimation of BNF in this species shows that about 70% N present in the shoot is derived from the atmosphere. (author)

Analysis of gene evolution and metabolic pathways using the Candida Gene Order Browser

LENUS (Irish Health Repository)

Fitzpatrick, David A

2010-05-10

Abstract Background Candida species are the most common cause of opportunistic fungal infection worldwide. Recent sequencing efforts have provided a wealth of Candida genomic data. We have developed the Candida Gene Order Browser (CGOB), an online tool that aids comparative syntenic analyses of Candida species. CGOB incorporates all available Candida clade genome sequences including two Candida albicans isolates (SC5314 and WO-1) and 8 closely related species (Candida dubliniensis, Candida tropicalis, Candida parapsilosis, Lodderomyces elongisporus, Debaryomyces hansenii, Pichia stipitis, Candida guilliermondii and Candida lusitaniae). Saccharomyces cerevisiae is also included as a reference genome. Results CGOB assignments of homology were manually curated based on sequence similarity and synteny. In total CGOB includes 65617 genes arranged into 13625 homology columns. We have also generated improved Candida gene sets by merging\\/removing partial genes in each genome. Interrogation of CGOB revealed that the majority of tandemly duplicated genes are under strong purifying selection in all Candida species. We identified clusters of adjacent genes involved in the same metabolic pathways (such as catabolism of biotin, galactose and N-acetyl glucosamine) and we showed that some clusters are species or lineage-specific. We also identified one example of intron gain in C. albicans. Conclusions Our analysis provides an important resource that is now available for the Candida community. CGOB is available at http:\\/\\/cgob.ucd.ie.

Chalcone Synthase (CHS) Gene Suppression in Flax Leads to Changes in Wall Synthesis and Sensing Genes, Cell Wall Chemistry and Stem Morphology Parameters

Science.gov (United States)

Zuk, Magdalena; Działo, Magdalena; Richter, Dorota; Dymińska, Lucyna; Matuła, Jan; Kotecki, Andrzej; Hanuza, Jerzy; Szopa, Jan

2016-01-01

The chalcone synthase (CHS) gene controls the first step in the flavonoid biosynthesis. In flax, CHS down-regulation resulted in tannin accumulation and reduction in lignin synthesis, but plant growth was not affected. This suggests that lignin content and thus cell wall characteristics might be modulated through CHS activity. This study investigated the possibility that CHS affects cell wall sensing as well as polymer content and arrangement. CHS-suppressed and thus lignin-reduced plants showed significant changes in expression of genes involved in both synthesis of components and cell wall sensing. This was accompanied by increased levels of cellulose and hemicellulose. CHS-reduced flax also showed significant changes in morphology and arrangement of the cell wall. The stem tissue layers were enlarged averagely twofold compared to the control, and the number of fiber cells more than doubled. The stem morphology changes were accompanied by reduction of the crystallinity index of the cell wall. CHS silencing induces a signal transduction cascade that leads to modification of plant metabolism in a wide range and thus cell wall structure. PMID:27446124

A preliminary study on the definitions and differences of main types of business arrangements

Directory of Open Access Journals (Sweden)

Anderson Tiago Peixoto Gonçalves

2012-08-01

Full Text Available With the growth of competitiveness and market requirements, several companies have been jointly organized with the aim of forming partnerships, forming the so-called Business Arrangements, to ensure that competitive advantages are achieved. This article came from the need to review the definitions and differences between the main types of existing Business Arrangements, as in the literature have been used different nomenclatures and classifications, either in terms of how the Arrangement is managed, how it is organized, the according to which members carry out their activities, how is the flow of resources and information, the degree of coordination and interaction, the form of production organization, and the strategies adopted. It is a basic research, descriptive and literature, which sought to collect the relevant sources, definitions about each Arrangement to meet the goal of the article is to study the definitions and differences between the main types of Business Arrangements. The article is justified by the scarcity of uniform definitions in the literature that make it possible to visualize the differences between each of the types of Arrangements, especially those in which the definitions are more similar.

Schemas of Marital Change: From Arranged Marriages to Eloping for Love.

Science.gov (United States)

Allendorf, Keera

2013-04-01

In recent decades, arranged marriages have become less common in many parts of Asia. This paper explores people's schemas surrounding just such a marital change in one Indian village using semi-structured interviews ( N =30) and ethnographic fieldwork. Respondents categorize marriages into two main types: arranged marriages and elopements, also called love marriages. Arranged marriages were common in the past, while elopements are now dominant. Both types of marriages have characteristics that are perceived positively and the ideal marriage is a hybrid of the two. Respondents ascribe the rise of love marriages to educational expansion, technological change, and foreign influence. Many also see it as an inevitable part of a larger process of socio-economic change. These schemas are strongly shaped by global influences, but also reflect multiple layers of local beliefs and cultures.

All-dielectric metamaterial frequency selective surface based on spatial arrangement ceramic resonators

Science.gov (United States)

Li, Liyang; Wang, Jun; Feng, Mingde; Ma, Hua; Wang, Jiafu; Du, Hongliang; Qu, Shaobo

In this paper, we demonstrate a method of designing all-dielectric metamaterial frequency selective surface (FSS) with ceramic resonators in spatial arrangement. Compared with the traditional way, spatial arrangement provides a flexible way to handle the permutation and combination of different ceramic resonators. With this method, the resonance response can be adjusted easily to achieve pass/stop band effects. As an example, a stop band spatial arrangement all-dielectric metamaterial FSS is designed. Its working band is in 11.65-12.23GHz. By adjusting permittivity and geometrical parameters of ceramic resonators, we can easily modulate the resonances, band pass or band stop characteristic, as well as the working band.

26 CFR 1.61-22 - Taxation of split-dollar life insurance arrangements.

Science.gov (United States)

2010-04-01

... 26 Internal Revenue 2 2010-04-01 2010-04-01 false Taxation of split-dollar life insurance..., and Taxable Income § 1.61-22 Taxation of split-dollar life insurance arrangements. (a) Scope—(1) In general. This section provides rules for the taxation of a split-dollar life insurance arrangement for...

The complete mitochondrial genome of Setaria digitata (Nematoda: Filarioidea): Mitochondrial gene content, arrangement and composition compared with other nematodes.

Science.gov (United States)

Yatawara, Lalani; Wickramasinghe, Susiji; Rajapakse, R P V J; Agatsuma, Takeshi

2010-09-01

In the present study, we determined the complete mitochondrial (mt) genome sequence (13,839bp) of parasitic nematode Setaria digitata and its structure and organization compared with Onchocerca volvulus, Dirofilaria immitis and Brugia malayi. The mt genome of S. digitata is slightly larger than the mt genomes of other filarial nematodes. S. digitata mt genome contains 36 genes (12 protein-coding genes, 22 transfer RNAs and 2 ribosomal RNAs) that are typically found in metazoans. This genome contains a high A+T (75.1%) content and low G+C content (24.9%). The mt gene order for S. digitata is the same as those for O. volvulus, D. immitis and B. malayi but it is distinctly different from other nematodes compared. The start codons inferred in the mt genome of S. digitata are TTT, ATT, TTG, ATG, GTT and ATA. Interestingly, the initiation codon TTT is unique to S. digitata mt genome and four protein-coding genes use this codon as a translation initiation codon. Five protein-coding genes use TAG as a stop codon whereas three genes use TAA and four genes use T as a termination codon. Out of 64 possible codons, only 57 are used for mitochondrial protein-coding genes of S. digitata. T-rich codons such as TTT (18.9%), GTT (7.9%), TTG (7.8%), TAT (7%), ATT (5.7%), TCT (4.8%) and TTA (4.1%) are used more frequently. This pattern of codon usage reflects the strong bias for T in the mt genome of S. digitata. In conclusion, the present investigation provides new molecular data for future studies of the comparative mitochondrial genomics and systematic of parasitic nematodes of socio-economic importance. 2010 Elsevier B.V. All rights reserved.

Mycobacteria contain two groEL genes: the second Mycobacterium leprae groEL gene is arranged in an operon with groES

NARCIS (Netherlands)

Rinke de Wit, T. F.; Bekelie, S.; Osland, A.; Miko, T. L.; Hermans, P. W.; van Soolingen, D.; Drijfhout, J. W.; Schöningh, R.; Janson, A. A.; Thole, J. E.

1992-01-01

In contrast to other bacterial species, mycobacteria were thus far considered to contain groEL and groES genes that are present on separate loci on their chromosomes, Here, by screening a Mycobacterium leprae lambda gt11 expression library with serum from an Ethiopian lepromatous leprosy patient,

Investigation of the optimal detector arrangement for the helmet-chin PET – A simulation study

Energy Technology Data Exchange (ETDEWEB)

Ahmed, Abdella M., E-mail: abdellanur@gmail.com; Tashima, Hideaki; Yoshida, Eiji; Yamaya, Taiga, E-mail: yamaya.taiga@qst.go.jp

2017-06-21

High sensitivity and high spatial resolution dedicated brain PET scanners are in high demand for early diagnosis of neurodegenerative diseases and studies of brain functions. To meet the demand, we have proposed the helmet-chin PET geometry which has a helmet detector and a chin detector. Our first prototype scanner used 54 4-layer depth-of-interaction (DOI) detectors. The helmet detector of the scanner had three detector rings with different radii arranged on a surface of a hemisphere (with a radius of 126.5 mm) and a top cover detector. Therefore, in this study, for our next development, we propose a spherical arrangement, in which the central axis of each detector points toward the center of the hemisphere, and we optimize the size of the detector crystal block to be arranged on the helmet detector. We simulate the spherical arrangement with the optimized crystal block size and compare its imaging performance with the multi-ring arrangement, which has a similar detector arrangement to that of our first prototype. We conduct Monte Carlo simulation to model the scanners having the 4-layer DOI detectors which consist of LYSO crystals. A dead space of 2 mm is assumed on each side of the crystal blocks such as for wrapping. The size of the crystal block is varied from 4×4 mm{sup 2} to 54×54 mm{sup 2} while fixing the thickness of the crystal block to 20 mm. We find that the crystal block sized at 42×42 mm{sup 2} has the highest sensitivity for a hemispherical phantom. The comparison of the two arrangements with the optimized crystal blocks show that, for the same number of crystal blocks, the spherical arrangement has 17% higher sensitivity for the hemispherical phantom than the multi-ring arrangement. We conclude that the helmet-chin PET with the spherical arrangement constructed from the crystal block sized at 42×42×20 mm{sup 3} has better imaging performance especially at the upper part of the brain compared to the multi-ring arrangement while keeping similar

Fuel arrangement for high temperature gas cooled reactor

International Nuclear Information System (INIS)

Tobin, J.M.

1978-01-01

Disclosed is a fuel arrangement for a high temperature gas cooled reactor including fuel assemblies with separate directly cooled fissile and fertile fuel elements removably inserted in an elongated moderator block also having a passageway for control elements

Institutional arrangements in the emerging biodiesel industry: Case studies from Minas Gerais—Brazil

NARCIS (Netherlands)

Watanabe, K.; Bijman, J.; Slingerland, M.A.

2012-01-01

Connecting (small) family farmers to the emerging biodiesel industry requires careful design of the institutional arrangements between the producers of oil crops and the processing companies. According to institutional economics theory, the design of effective and efficient arrangements depends on

Inductive circuit arrangements

International Nuclear Information System (INIS)

Mansfield, Peter; Coxon, R.J.

1987-01-01

A switched coil arrangement is connected in a bridge configuration of four switches S 1 , S 2 , S 3 and S 4 which are each shunted by diodes D 1 , D 2 , D 3 and D 4 so that current can flow in either direction through a coil L depending on the setting of the switches. A capacitor C is connected across the bridge through a switch S 5 to receive the inductive energy stored in coil L on breaking the current flow path through the coil. The electrostatic energy stored in capacitor C can then be used to supply current through the coil in the reverse direction either immediately or after a time delay. Coil L may be a superconductive coil. Losses in the circuit can be made up by a trickle charge of capacitor C from a separate supply V 2 . The device may be used in nuclear magnetic resonance imaging. (author)

3-D printed composites with ultrasonically arranged complex microstructure

Science.gov (United States)

Llewellyn-Jones, Thomas M.; Drinkwater, Bruce W.; Trask, Richard S.

2016-04-01

This paper demonstrates the efficacy of implementing ultrasonic manipulation within a modified form of stereolithographic 3D printing to form complex microstructures in printed components. Currently 3D printed components are limited both in terms of structural performance and specialised functionality. This study aims to demonstrate a novel method for 3D printing composite materials, by arranging microparticles suspended within a photocurable resin. The resin is selectively cured by a 3-axis gantry-mounted 405nm laser. Ultrasonic forces are used to arrange the microfibres into predetermined patterns within the resin, with unidirectional microfibre alignment and a hexagonal lattice structure demonstrated. An example of dynamic microstructure variation within a single print layer is also presented.

Magneto-optical imaging of vortex arrangements in Pb finite superconducting networks

International Nuclear Information System (INIS)

Tsuchiya, Y.; Nakajima, Y.; Tamegai, T.

2009-01-01

We have fabricated finite-sized Pb superconducting networks with 10 x 10 square (each 6 x 6 μm 2 ) holes by using the electron beam lithography and vortex arrangements are visualized by using magneto-optical imaging. We find that the vortex penetration at low temperature is controlled by defects in the network. We also find nearly regular arrangements of vortices with defects close to 1/2 and1/3 of the matching field.

Institutional Arrangement of Financial Markets Supervision: The Case of the Czech Republic

OpenAIRE

Musílek, Petr

2008-01-01

The paper deals with institutional arrangement of financial supervision in the Czech Republic. Financial markets are composed of partial financial segments specialized in individual types of financial instruments and individual customer groups. Financial institutions gradually transform into financial supermarkets. There are several models of institutional arrangement of financial supervision (integrated financial supervision model, sectional financial supervision model, financial supervision...

Review of arrangements for the recent transportation of radioactive waste

Energy Technology Data Exchange (ETDEWEB)

Codd, M H

1995-07-01

The terms of reference of this review were: to examine the adequacy of the arrangements made for the transport of contaminated material from Lucas Heights and St Marys to Woomera, in terms of compliance with the Australian Code for the Safe Transport of Radioactive Substances 1990; to report to the Minister for Industry, Science and Technology on the quality of the planning and preparation for the move; the safety and effectiveness of the move itself; the adequacy of response to any `incidents` involved in the move, and of contingency arrangements; whether planning and transport arrangements might be improved for the future. Thus, the Review was focussed on movements of material in two specific cases - material owned by the CSIRO and stored at Lucas Heights and material owned by the Department of Defence and stored at St Marys. The report concludes that the movements of wastes were carried out consistent with the Transport Code, without any risk to public safety. Additional relevant information in support of the review is contained in 8 appendixes.

Review of arrangements for the recent transportation of radioactive waste

International Nuclear Information System (INIS)

Codd, M.H.

1995-07-01

The terms of reference of this review were: to examine the adequacy of the arrangements made for the transport of contaminated material from Lucas Heights and St Marys to Woomera, in terms of compliance with the Australian Code for the Safe Transport of Radioactive Substances 1990; to report to the Minister for Industry, Science and Technology on the quality of the planning and preparation for the move; the safety and effectiveness of the move itself; the adequacy of response to any 'incidents' involved in the move, and of contingency arrangements; whether planning and transport arrangements might be improved for the future. Thus, the Review was focussed on movements of material in two specific cases - material owned by the CSIRO and stored at Lucas Heights and material owned by the Department of Defence and stored at St Marys. The report concludes that the movements of wastes were carried out consistent with the Transport Code, without any risk to public safety. Additional relevant information in support of the review is contained in 8 appendixes

Accountability after Structural Disaggregation: Comparing Agency Accountability Arrangements

NARCIS (Netherlands)

Overman, Sjors; Van Genugten, Marieke; Van Thiel, Sandra

2015-01-01

New accountability instruments – performance indicators, audits, and financial incentives – are expected to replace traditional accountability instruments in NPM reforms. We test this expectation by looking at the accountability arrangements of semi-autonomous agencies as a typical example of NPM

Genetic exchange versus genetic differentiation in a medium-sized inversion of Drosophila: the A2/Ast arrangements of Drosophila subobscura.

Science.gov (United States)

Nóbrega, Clévio; Khadem, Mahnaz; Aguadé, Montserrat; Segarra, Carmen

2008-08-01

Chromosomal inversion polymorphism affects nucleotide variation at loci associated with inversions. In Drosophila subobscura, a species with a rich chromosomal inversion polymorphism and the largest recombinational map so far reported in the Drosophila genus, extensive genetic structure of nucleotide variation was detected in the segment affected by the O(3) inversion, a moderately sized inversion at Muller's element E. Indeed, a strong genetic differentiation all over O(3) and no evidence of a higher genetic exchange in the center of the inversion than at breakpoints were detected. In order to ascertain, whether other polymorphic and differently sized inversions of D. subobscura also exhibited a strong genetic structure, nucleotide variation in 5 gene regions (P236, P275, P150, Sxl, and P125) located along the A(2) inversion was analyzed in A(st) and A(2) chromosomes of D. subobscura. A(2) is a medium-sized inversion at Muller's element A and forms a single inversion loop in heterokaryotypes. The lower level of variation in A(2) relative to A(st) and the significant excess of low-frequency variants at polymorphic sites indicate that nucleotide variation at A(2) is not at mutation-drift equilibrium. The closest region to an inversion breakpoint, P236, exhibits the highest level of genetic differentiation (F(ST)) and of linkage disequilibrium (LD) between arrangements and variants at nucleotide polymorphic sites. The remaining 4 regions show a higher level of genetic exchange between A(2) and A(st) chromosomes than P236, as revealed by F(ST) and LD estimates. However, significant genetic differentiation between the A(st) and A(2) arrangements was detected not only at P236 but also in the other 4 regions separated from the nearest breakpoint by 1.2-2.9 Mb. Therefore, the extent of genetic exchange between arrangements has not been high enough to homogenize nucleotide variation in the center of the A(2) inversion. A(2) can be considered a typical successful inversion

Changes in living arrangements and mortality among older people in China

Directory of Open Access Journals (Sweden)

Zhixin Feng

2017-12-01

Full Text Available Living arrangements in later life are dynamic, with changes associated with life events such as widowhood or moves into an institution. Previous research has found particular changes in living arrangements to be associated with an elevated risk of mortality. However, research in this area within the context of China is limited, despite China being home to the world's largest population of older people. This study investigates the impact of changes in living arrangements on older persons’ survival using the Chinese Longitudinal Healthy Longevity Survey from 2002 to 2011. The original sample was 16,064 in 2002, and this study includes 6191 individuals who survived in 2005 and had complete information of track record in later waves. Changes in living arrangements are examined between 2002 and 2005. Cox-proportional hazards models are then used to investigate the association between the dynamics of living arrangements and respondents’ survival status from 2005 to 2011 . Results show that men and women who lived in an institution in both 2002 and 2005, or who moved into an institution from living with family faced a greater risk of dying compared to those continuing to live with family. By contrast, continuing to live with family or alone, or moving between living with family and living alone, were not associated with an increased mortality risk, although there were some differences by gender. The institutional care sector in China is still in its infancy, with provision based on ability to pay market fees rather than need associated with age-related function impairment. The findings show that living in, or moving into, an institution is associated with a high mortality risk therefore requires further investigation in the context of a rapidly changing Chinese society.

Support system, excavation arrangement, and process of supporting an object

Science.gov (United States)

Arnold, Bill W.

2017-08-01

A support system, an excavation arrangement, and a process of supporting an object are disclosed. The support system includes a weight-bearing device and a camming mechanism positioned below the weight-bearing device. A downward force on the weight-bearing device at least partially secures the camming mechanism to opposing surfaces. The excavation arrangement includes a borehole, a support system positioned within and secured to the borehole, and an object positioned on and supported by the support system. The process includes positioning and securing the support system and positioning the object on the weight-bearing device.

Specific gene mutations induced by heavy ions

International Nuclear Information System (INIS)

Freeling, M.; Karoly, C.W.; Cheng, D.S.K.

1980-01-01

This report summarizes our heavy-ion research rationale, progress, and plans for the near future. The major project involves selecting a group of maize Adh1 mutants induced by heavy ions and correlating their altered behavior with altered DNA nucleotide sequences and sequence arrangements. This research requires merging the techniques of classical genetics and recombinant DNA technology. Our secondary projects involve (1) the use of the Adh gene in the fruit fly, Drosophila melanogaster, as a second system with which to quantify the sort of specific gene mutants induced by heavy ions as compared to x rays, and (2) the development of a maize Adh1 pollen in situ monitor for environmental mutagens

Atomic arrangement in immiscible Ag–Cu alloys synthesized far-from-equilibrium

International Nuclear Information System (INIS)

Elofsson, V.; Almyras, G.A.; Lü, B.; Boyd, R.D.; Sarakinos, K.

2016-01-01

Physical attributes of multicomponent materials of a given chemical composition are determined by atomic arrangement at property-relevant length scales. A potential route to access a vast array of atomic configurations for material property tuning is by synthesis of multicomponent thin films using vapor fluxes with their deposition pattern modulated in the sub-monolayer regime. However, the applicability of this route for creating new functional materials is impeded by the fact that a fundamental understanding of the combined effect of sub-monolayer flux modulation, kinetics and thermodynamics on atomic arrangement is not available in the literature. Here we present a research strategy and verify its viability for addressing the aforementioned gap in knowledge. This strategy encompasses thin film synthesis using a route that generates multi-atomic fluxes with sub-monolayer resolution and precision over a wide range of experimental conditions, deterministic growth simulations and nanoscale microstructural probes. Investigations are focused on structure formation within the archetype immiscible Ag-Cu binary system, revealing that atomic arrangement at different length scales is governed by the arrival pattern of the film forming species, in conjunction with diffusion of near-surface Ag atoms to encapsulate 3D Cu islands growing on 2D Ag layers. The knowledge generated and the methodology presented herein provides the scientific foundation for tailoring atomic arrangement and physical properties in a wide range of miscible and immiscible multinary systems.

The ORSEC arrangement and the 'nuclear' intervention specific plan

International Nuclear Information System (INIS)

Guenon, C.

2010-01-01

In order to take the specific character of a nuclear emergency situation into account, France has developed planning tools within the so-called Crisis National Organisation (ONC, organisation nationale de crise). This organisation involves public bodies, agencies and companies. Thus, intervention specific plans (PPI, plans particuliers d'intervention) are included in the ORSEC general arrangement. The assessment of geographical and chronological consequences of a nuclear accident has lead to the definition of two main categories of measures, depending on the fact they are immediately or progressively applied. They involve the intervention of specialised means. This report also indicates how new measures have been introduced in the ORSEC arrangement to manage the post-accident phase. The author also outlines that crisis communication must also be prepared and tested

Arrangements for dealing with emergencies at civil nuclear installations

International Nuclear Information System (INIS)

Turner, M.J.; Robinson, I.F.

1989-01-01

This paper covers arrangements for dealing with nuclear emergencies at sites licensed by the Health and Safety Executive/Nuclear Installations Inspectorate. Such arrangements are over and above the contingency plans required for radiation incidents as required by the Ionising Radiations Regulations. The statutory position of the NII is described and, although the NII is limited to regulating the activities of the operator, the functions of the other organisations that could be involved in dealing with an emergency are briefly covered in order to give as complete a picture as possible. The basis for emergency planning is given together with the consequences and countermeasures for mitigation of a nuclear emergency, including the use of ERLs. The requirements for emergency exercises are explained. (author)

Repeated reunions and splits feature the highly dynamic evolution of 5S and 35S ribosomal RNA genes (rDNA) in the Asteraceae family.

Science.gov (United States)

Garcia, Sònia; Panero, José L; Siroky, Jiri; Kovarik, Ales

2010-08-16

In flowering plants and animals the most common ribosomal RNA genes (rDNA) organisation is that in which 35S (encoding 18S-5.8S-26S rRNA) and 5S genes are physically separated occupying different chromosomal loci. However, recent observations established that both genes have been unified to a single 35S-5S unit in the genus Artemisia (Asteraceae), a genomic arrangement typical of primitive eukaryotes such as yeast, among others. Here we aim to reveal the origin, distribution and mechanisms leading to the linked organisation of rDNA in the Asteraceae by analysing unit structure (PCR, Southern blot, sequencing), gene copy number (quantitative PCR) and chromosomal position (FISH) of 5S and 35S rRNA genes in approximately 200 species representing the family diversity and other closely related groups. Dominant linked rDNA genotype was found within three large groups in subfamily Asteroideae: tribe Anthemideae (93% of the studied cases), tribe Gnaphalieae (100%) and in the "Heliantheae alliance" (23%). The remaining five tribes of the Asteroideae displayed canonical non linked arrangement of rDNA, as did the other groups in the Asteraceae. Nevertheless, low copy linked genes were identified among several species that amplified unlinked units. The conserved position of functional 5S insertions downstream from the 26S gene suggests a unique, perhaps retrotransposon-mediated integration event at the base of subfamily Asteroideae. Further evolution likely involved divergence of 26S-5S intergenic spacers, amplification and homogenisation of units across the chromosomes and concomitant elimination of unlinked arrays. However, the opposite trend, from linked towards unlinked arrangement was also surmised in few species indicating possible reversibility of these processes. Our results indicate that nearly 25% of Asteraceae species may have evolved unusual linked arrangement of rRNA genes. Thus, in plants, fundamental changes in intrinsic structure of rDNA units, their copy

An ergonomics based design research method for the arrangement of helicopter flight instrument panels.

Science.gov (United States)

Alppay, Cem; Bayazit, Nigan

2015-11-01

In this paper, we study the arrangement of displays in flight instrument panels of multi-purpose civil helicopters following a user-centered design method based on ergonomics principles. Our methodology can also be described as a user-interface arrangement methodology based on user opinions and preferences. This study can be outlined as gathering user-centered data using two different research methods and then analyzing and integrating the collected data to come up with an optimal instrument panel design. An interview with helicopter pilots formed the first step of our research. In that interview, pilots were asked to provide a quantitative evaluation of basic interface arrangement principles. In the second phase of the research, a paper prototyping study was conducted with same pilots. The final phase of the study entailed synthesizing the findings from interviews and observational studies to formulate an optimal flight instrument arrangement methodology. The primary results that we present in our paper are the methodology that we developed and three new interface arrangement concepts, namely relationship of inseparability, integrated value and locational value. An optimum instrument panel arrangement is also proposed by the researchers. Copyright © 2015 Elsevier Ltd and The Ergonomics Society. All rights reserved.

Numerical investigation of thermal performance of a water-cooled mini-channel heat sink for different chip arrangement

Energy Technology Data Exchange (ETDEWEB)

Tikadar, Amitav, E-mail: amitav453@gmail.com; Hossain, Md. Mahamudul; Morshed, A. K. M. M. [Department of Mechanical Engineering, Bangladesh University of Engineering and Technology, Dhaka, 1000 (Bangladesh)

2016-07-12

Heat transfer from electronic chip is always challenging and very crucial for electronic industry. Electronic chips are assembled in various manners according to the design conditions and limitationsand thus the influence of chip assembly on the overall thermal performance needs to be understand for the efficient design of electronic cooling system. Due to shrinkage of the dimension of channel and continuous increment of thermal load, conventional heat extraction techniques sometimes become inadequate. Due to high surface area to volume ratio, mini-channel have the natural advantage to enhance convective heat transfer and thus to play a vital role in the advanced heat transfer devices with limited surface area and high heat flux. In this paper, a water cooled mini-channel heat sink was considered for electronic chip cooling and five different chip arrangements were designed and studied, namely: the diagonal arrangement, parallel arrangement, stacked arrangement, longitudinal arrangement and sandwiched arrangement. Temperature distribution on the chip surfaces was presented and the thermal performance of the heat sink in terms of overall thermal resistance was also compared. It is found that the sandwiched arrangement of chip provides better thermal performance compared to conventional in line chip arrangement.

Determinants of Choice of Institutional Marketing Arrangements by ...

African Journals Online (AJOL)

Determinants of Choice of Institutional Marketing Arrangements by Small Poultry Businesses in Tanzania: Application of Transaction Cost Theory. ... It indicates in addition that, probability of PFBs to enter into contractual businesses falls with increase in Transaction Costs (TCs). Linear regression analysis shows, in addition ...

26 CFR 1.414(w)-1 - Permissible withdrawals from eligible automatic contribution arrangements.

Science.gov (United States)

2010-04-01

... contribution arrangements. 1.414(w)-1 Section 1.414(w)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT... Plans, Etc. § 1.414(w)-1 Permissible withdrawals from eligible automatic contribution arrangements. (a) Overview. Section 414(w) provides rules under which certain employees are permitted to elect to make a...

46 CFR 133.40 - Evaluation, testing and approval of lifesaving appliances and arrangements.

Science.gov (United States)

2010-10-01

... appliances and arrangements. 133.40 Section 133.40 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY... lifesaving appliances and arrangements. (a) Each item of lifesaving equipment required by this part to be... OCMI for use on the OSV. (c) The Commandant (CG-521) may accept a novel lifesaving appliance or...

Access to flexible work arrangements, working-time fit and job satisfaction

OpenAIRE

D.S. Possenriede; J. Plantenga

2011-01-01

This article analyses the effects of access to flexible work arrangements, namely flexi-time, telehomework and part-time work, on employees’ satisfaction with the fit between paid work and private life and their overall job satisfaction. Having access to flexible work arrangements gives employees more control over their working life and thereby improves on the match between paid work and private life. Based on unique cross-sectional survey data collected among more than 20.000 Dutch public ...

Identification of unique cis-element pattern on simulated microgravity treated Arabidopsis by in silico and gene expression

Science.gov (United States)

Soh, Hyuncheol; Choi, Yongsang; Lee, Taek-Kyun; Yeo, Up-Dong; Han, Kyeongsik; Auh, Chungkyun; Lee, Sukchan

2012-08-01

Arabidopsis gene expression microarray (44 K) was used to detect genes highly induced under simulated microgravity stress (SMS). Ten SMS-inducible genes were selected from the microarray data and these 10 genes were found to be abundantly expressed in 3-week-old plants. Nine out of the 10 SMS-inducible genes were also expressed in response to the three abiotic stresses of drought, touch, and wounding in 3-week-old Arabidopsis plants respectively. However, WRKY46 was elevated only in response to SMS. Six other WRKY genes did not respond to SMS. To clarify the characteristics of the genes expressed at high levels in response to SMS, 20 cis-elements in the promoters of the 40 selected genes including the 10 SMS-inducible genes, the 6 WRKY genes, and abiotic stress-inducible genes were analyzed and their spatial positions on each promoter were determined. Four cis-elements (M/T-G-T-P from MYB1AT or TATABOX5, GT1CONSENSUS, TATABOX5, and POLASIG1) showed a unique spatial arrangement in most SMS-inducible genes including WRKY46. Therefore the M/T-G-T-P cis-element patterns identified in the promoter of WRKY46 may play important roles in regulating gene expression in response to SMS. The presences of the cis-element patterns suggest that the order or spatial positioning of certain groups of cis-elements is more important than the existence or numbers of specific cis-elements. Taken together, our data indicate that WRKY46 is a novel SMS inducible transcription factor and the unique spatial arrangement of cis-elements shown in WRKY46 promoter may play an important role for its response to SMS.

The Life Course of Children Born to Unmarried Mothers: Childhood Living Arrangements and Young Adult Outcomes.

Science.gov (United States)

Aquilino, William S.

1996-01-01

Explored living arrangements among children born to unmarried mothers and the impact of childhood living arrangements on the young adult's life course. Analyses showed that living arrangement patterns after birth to a single mother influenced the likelihood of high school completion, post secondary education, and other conditions. (RJM)

Second Harmonic Generation Imaging Analysis of Collagen Arrangement in Human Cornea.

Science.gov (United States)

Park, Choul Yong; Lee, Jimmy K; Chuck, Roy S

2015-08-01

To describe the horizontal arrangement of human corneal collagen bundles by using second harmonic generation (SHG) imaging. Human corneas were imaged with an inverted two photon excitation fluorescence microscope. The excitation laser (Ti:Sapphire) was tuned to 850 nm. Backscatter signals of SHG were collected through a 425/30-nm bandpass emission filter. Multiple, consecutive, and overlapping image stacks (z-stacks) were acquired to generate three dimensional data sets. ImageJ software was used to analyze the arrangement pattern (irregularity) of collagen bundles at each image plane. Collagen bundles in the corneal lamellae demonstrated a complex layout merging and splitting within a single lamellar plane. The patterns were significantly different in the superficial and limbal cornea when compared with deep and central regions. Collagen bundles were smaller in the superficial layer and larger in deep lamellae. By using SHG imaging, the horizontal arrangement of corneal collagen bundles was elucidated at different depths and focal regions of the human cornea.

Performance model of metallic concentric tube recuperator with counter flow arrangement

Energy Technology Data Exchange (ETDEWEB)

Sharma, Harshdeep [HIET, Department of Mechanical Engineering, Ghaziabad, Uttar Pradesh (India); Kumar, Anoop; Goel, Varun [NIT, Department of Mechanical Engineering, Hamirpur, Himachal Pradesh (India)

2010-03-15

A performance model for counter flow arrangement in concentric tube recuperator that can be used to utilize the waste heat in the temperature range of 900-1,400 C is presented. The arrangement consists of metallic tubular inner and outer concentric shell with a small annular gap between two concentric shells. Flue gases pass through the inner shell while air passes through the annular gap in the reverse direction (counter flow arrangement). The height of the recuperator is divided into elements and an energy balance is performed on each elemental height. Results give necessary information about surface, gas and air temperature distribution, and the influence of operating conditions on recuperator performance. The recuperative effectiveness is found to be increased with increasing inlet gas temperature and decreased with increasing fuel flow rate. The present model accounts for all heat transfer processes pertinent to a counterflow radiation recuperator and provide a valuable tool for performance considerations. (orig.)

Why Employers Use Flexible Staffing Arrangements: Evidence from an Establishment Survey. Upjohn Institute Staff Working Paper.

Science.gov (United States)

Houseman, Susan N.

Use of flexible staffing arrangements--including temporary help agency, short-term, on-call, regular part-time, and contract workers--is widespread and two-thirds of employers believe this trend will increase in the near future. A study examined which employers use flexible staffing arrangements, why they use these arrangements, and their…

42 CFR 411.357 - Exceptions to the referral prohibition related to compensation arrangements.

Science.gov (United States)

2010-10-01

... payment of remuneration in the form of a productivity bonus based on services performed personally by the... promotion of a business arrangement or other activity that violates any Federal or State law. (vii) A... services to be performed under the arrangement do not involve the counseling or promotion of a business...

Elements for regulating surrogacy arrangements with cross-border effects

Directory of Open Access Journals (Sweden)

Bordaš Bernadet

2013-01-01

Full Text Available Numerous cases of international surrogacy arrangements and their legal effects in different national legal frameworks have caused a need to weigh the possibility and necessity of regulating the issue on international level. The Hague Conference on Private International Law has been since 2011 involved in preliminary research activities of the issue, on the basis of which it will submit a final report in 2014 on the state of play and on the need to start drafting an international instrument. During the past three years two preliminary reports and four questionnaires have been submitted. Questionnaire 1 have been sent to the member states of the Conference and to other interested countries to collect data on crucial issues of surrogacy and its legal regulation in national legislations. Serbian law de lege lata prohibits surrogacy arrangements, but the 2011 Draft Civil Code introduces it to the domestic legal system as a tool of biomedically assisted fertilization. The present paper suggests that the regulation of surrogacy must also include surrogacy arrangements with cross-border effects for the sake of comprehensiveness of the future legal act on the issue. For this purpose, the paper indicates - based on the preliminary research conducted by the Hague Conference on Private International Law - those elements that should be included in future legislation of Serbia.

26 CFR 1.881-3 - Conduit financing arrangements.

Science.gov (United States)

2010-04-01

... satisfaction of a repayment obligation is not an advance of money or other property. A financing arrangement... facts and circumstances, including, without limitation, the factors set forth in paragraph (b)(2) of... predominantly of transactions with customers who are not related persons. An intermediate entity's trade or...

Workers in Alternative Employment Arrangements: A Second Look.

Science.gov (United States)

Cohany, Sharon R.

1998-01-01

Both the proportion and characteristics of workers in four alternative employment arrangements in February 1997 were little different from two years earlier. The groups--temporary-help-agency workers, contract company workers, workers who are on call, and independent contractors--continue to be highly diverse. (Author/JOW)

How regional non-proliferation arrangements complement international verification

International Nuclear Information System (INIS)

Carlson, J.

1999-01-01

This presentation focuses on international verification in the form of IAEA Safeguards, and discusses the relationship between IAEA safeguards and the relevant regional arrangements, both the existing and the future. For most States the political commitment against acquisition of nuclear weapons has been carefully reached and strongly held. Their observance of treaty commitments does not depend on the deterrent effect of verification activities. Safeguards serve to assist States who recognise it is in their own interest to demonstrate their compliance to others. Thus safeguards are a vital confidence building measure in their own right, as well as being a major complement to the broader range of international confidence building measures. Safeguards can both complement other confidence building measures and in turn be complemented by them. Within consideration of how it could work it is useful to consider briefly current developments of IAEA safeguards, i.e. existing regional arrangements and nuclear weapon free zones

A study on arrangement characteristics of microparticles in sedimentation on flat and round substrates

Science.gov (United States)

Yeo, Eunju; Son, Minhee; Kim, Kwanoh; Kim, Jeong Hwan; Yoo, Yeong-Eun; Choi, Doo-Sun; Kim, Jungchul; Yoon, Seok Ho; Yoon, Jae Sung

2017-12-01

Recent advances of microfabrication techniques have enabled diverse structures and devices on the microscale. This fabrication method using microparticles is one of the most promising technologies because it can provide a cost effective process for large areas. So, many researchers are studying modulation and manipulation of the microparticles in solution to obtain a proper arrangement. However, the microparticles are in sedimentation status during the process in many cases, which makes it difficult to control their arrangement. In this study, droplets containing microparticles were placed on a substrate with minimal force and we investigated the arrangement of these microparticles after evaporation of the liquid. Experiments have been performed with upward and downward substrates to change the direction of gravity. The geometry of substrates was also changed, which were flat or round. The results show that the arrangement depends on the size of particles and gravity and geometry of the substrate. The arrangement also depends on the movement of the contact line of the droplets, which may recede or be pinned during evaporation. This study is expected to provide a method of the fabrication process for microparticles which may not be easily manipulated due to sedimentation.

Tax issues in structuring gas process arrangements

International Nuclear Information System (INIS)

Iverach, R.J.

1999-01-01

The current status of various tax issues regarding ownership, operation and financing of gas processing facilities in Canada was discussed. Frequently, energy companies are not taxed because of their large pools of un-depreciated capital cost and other resource related accounts. In addition, their time horizons for taxability are being extended in line with the expansion of their businesses. However, other investors are fully taxable, hence they wish to shelter their income through the use of tax efficient investment arrangements. This paper provides a detailed description of the tax treatment of gas processing facilities, tax implications of various structures between the producer and the investor such as lease, processing fee arrangements etc., and use of 'Canadian Renewable and Conservation Expense' (CRCE) for cogeneration projects within processing plants. All these need to be considered before completing a financing transaction involving a gas processing facility, since the manner in which the transaction is completed will determine the advantages and benefits from an income tax perspective. The accounting and legal aspects must be similarly scrutinized to ensure that the intended results for all parties are achieved. 8 figs

Moduli of weighted hyperplane arrangements

CERN Document Server

Lahoz, Martí; Macrí, Emanuele; Stellari, Paolo

2015-01-01

This book focuses on a large class of geometric objects in moduli theory and provides explicit computations to investigate their families. Concrete examples are developed that take advantage of the intricate interplay between Algebraic Geometry and Combinatorics. Compactifications of moduli spaces play a crucial role in Number Theory, String Theory, and Quantum Field Theory – to mention just a few. In particular, the notion of compactification of moduli spaces has been crucial for solving various open problems and long-standing conjectures. Further, the book reports on compactification techniques for moduli spaces in a large class where computations are possible, namely that of weighted stable hyperplane arrangements.

Arrangement for selectively irradiating webs

International Nuclear Information System (INIS)

Ihme, B.

1975-01-01

The arrangement for selectively irradiating a web includes a perforated band of a radiation impermeable substance which is guided in an endless path via a pair of guide rollers and has two juxtaposed runs in this path. A take-up roller conveys a web of material past one of the runs at a side thereof remote from the other run, the direction of movement of the web being other than parallel to that of the band and, preferably, normal thereto. An electron accelerator is provided at the far side of the run remote from the web and is effective for directing a radiation beam at the web through the perforations

ARRANGEMENT OF LAW BY STATE FINANCIAL AUTHORITY IN REALIZING NATIONAL BANKING INDUSTRY THAT’S HEALTHY AND DYNAMIC

Directory of Open Access Journals (Sweden)

Muammar Arafat Yusmad

2015-12-01

Full Text Available he development of national banking nowadays are growing fast, competitive and integrative. One problem of Indonesian banking system related with practicing law arrangement which is a harmonization process toward legislations. The focus problems are: law arrangement in banking governance, the procedure of the law arrangement in achieving national bank industry which are healthy and dynamic. As intermediary institutions, bank should be in a healthy condition in order to gain public confidence and deserve to increase national economic growth. Based on the conceptual discussion, obtained arguments are: (1 The law arrangement of national banking should be done coodinately between Otoritas Jasa Keuangan (OJK and Bank Indonesia (BI; (2 Procedure of law arrangement according to the function and authority of OJK and BI which the urgent subjects are to avoid conflict of norm, overlapping policies and limited validity of norm of the law case which happen and will be happen; (3 banking law arrangement include bank arrangement and supervision system, strengthening internal condition of the bank, empowering and protecting consumer with complaints mechanism and follow-up which are clear and measurable.

Flexible working, individual performance and employee attitudes: comparing formal and informal arrangements

OpenAIRE

De Menezes, Lilian M.; Kelliher, Clare

2016-01-01

In the context of a wider trend to individualize HRM, this paper examines the relationship between flexible working arrangements and individual performance. Drawing on a range of theories, it examines potential indirect effects on employee performance via job satisfaction and organizational commitment and analyses whether these relationships vary according to whether the arrangement was set up through a formal process, or negotiated informally between the employee and their line manager. Exta...

Comparative anatomy of the human APRT gene and enzyme: nucleotide sequence divergence and conservation of a nonrandom CpG dinucleotide arrangement

International Nuclear Information System (INIS)

Broderick, T.P.; Schaff, D.A.; Bertino, A.M.; Dush, M.K.; Tischfield, J.A.; Stambrook, P.J.

1987-01-01

The functional human adenine phosphoribosyltransferase (APRT) gene is <2.6 kilobases in length and contains five exons. The amino acid sequences of APRTs have been highly conserved throughout evolution. The human enzyme is 82%, 90%, and 40% identical to the mouse, hamster, and Escherichia coli enzymes, respectively. The promoter region of the human APRT gene, like that of several other housekeeping genes, lacks TATA and CCAAT boxes but contains five GC boxes that are potential binding sites for the Sp1 transcription factor. The distal three, however, are dispensable for gene expression. Comparison between human and mouse APRT gene nucleotide sequences reveals a high degree of homology within protein coding regions but an absence of significant homology in 5' flanking, 3' untranslated, and intron sequences, except for similarly positioned GC boxes in the promoter region and a 26-base-pair region in intron 3. This 26-base-pair sequence is 92% identical with a similarly positioned sequence in the mouse gene and is also found in intron 3 of the hamster gene, suggesting that its retention may be a consequence of stringent selection. The positions of all introns have been precisely retained in the human and both rodent genes. Retention of an elevated CpG dinucleotide content, despite loss of sequence homology, suggests that there may be selection for CpG dinucleotides in these regions and that their maintenance may be important for APRT gene function

Recombination-dependent replication and gene conversion homogenize repeat sequences and diversify plastid genome structure.

Science.gov (United States)

Ruhlman, Tracey A; Zhang, Jin; Blazier, John C; Sabir, Jamal S M; Jansen, Robert K

2017-04-01

There is a misinterpretation in the literature regarding the variable orientation of the small single copy region of plastid genomes (plastomes). The common phenomenon of small and large single copy inversion, hypothesized to occur through intramolecular recombination between inverted repeats (IR) in a circular, single unit-genome, in fact, more likely occurs through recombination-dependent replication (RDR) of linear plastome templates. If RDR can be primed through both intra- and intermolecular recombination, then this mechanism could not only create inversion isomers of so-called single copy regions, but also an array of alternative sequence arrangements. We used Illumina paired-end and PacBio single-molecule real-time (SMRT) sequences to characterize repeat structure in the plastome of Monsonia emarginata (Geraniaceae). We used OrgConv and inspected nucleotide alignments to infer ancestral nucleotides and identify gene conversion among repeats and mapped long (>1 kb) SMRT reads against the unit-genome assembly to identify alternative sequence arrangements. Although M. emarginata lacks the canonical IR, we found that large repeats (>1 kilobase; kb) represent ∼22% of the plastome nucleotide content. Among the largest repeats (>2 kb), we identified GC-biased gene conversion and mapping filtered, long SMRT reads to the M. emarginata unit-genome assembly revealed alternative, substoichiometric sequence arrangements. We offer a model based on RDR and gene conversion between long repeated sequences in the M. emarginata plastome and provide support that both intra-and intermolecular recombination between large repeats, particularly in repeat-rich plastomes, varies unit-genome structure while homogenizing the nucleotide sequence of repeats. © 2017 Botanical Society of America.

Morphophysiology and nutritive value of signalgrass in silvipastoral system with different tree arrangements

Directory of Open Access Journals (Sweden)

Joysiene Sanguinete Coelho

2014-06-01

Full Text Available The study was carried out with the aim to evaluate the effect of different special arrangements in forage yield, nutritive value and structure of the understory of signalgrass (Brachiaria decumbens in silvipastoral system with different regrowth times. The design was in complete randomized block with tree replicates in a factorial scheme with split-plots 2 × 2 × 5 consisting two spatial arrangements [Double lines 9 × (2 × 2m and simple lines (9 × 2m] in two sampling places (in the middle of the intercropping and under the three canopy in the plot and five regrowth times (35, 42, 49, 56 e 63 days in the split-plot. It was used a silvipastoral system established since June, 2008 in degraded pasture with signalgrass predominance. The pasture was homogenized by grazing at 15 cm from the soil level. Were evaluated the dry matter yield leaf:stem ratio, light interception and leaf area index. In addition were evaluated the nutritive value characteristics dry matter content, neutral and acid detergent fiber, crude protein and lignin. The photosynthetic active radiation was monitored. The use of simple or double lines did not influence the leaf area index, light interception and dry mass yield. The leaf:stem ratio was influenced by the sampling place only in the double line arrangement. The neutral detergent fiber was substantially high in the double line arrangement. Therefore, the use of double lines reduces the photosynthetic active radiation amount incident in the understory, but does not reduce the forage yield in relation to simple line arrangements. These results indicate the use of double lines arrangement may allow the harvest of more threes without reduce the pasture production.

Conflict Resolution: the Truncated Zoning Arrangement and the Buhari Political Tsunami in Nigeria

Directory of Open Access Journals (Sweden)

Isaac Terungwa Terwase

2015-08-01

Full Text Available The Nigerian Fourth Republic ushered in a demo-cratically elected government in 1999 that paved way for the civilians to take over government after a long period of military rule in Nigeria. This made the political parties to project their candidates for contest in occupying the political positions at the federal, states and local government levels. Thus, such projection through the ruling political party that won the election in 1999 known as the People’s Democratic Party (PDP, went into zoning arrange-ment that could give the country’s six geopolitical zones a place for participation in the administration of the country. This arrangement coordinated the highest positions such as the President, Vice-Presi-dent, President of the Senate, Speaker of the House of Representatives, Secretary to the Government of the Federation, and Chairman of the ruling party. However, such arrangements were only practiced from 1999 to 2011. The zoning arrangements were trun-cated in 2011, which led to conflict in the Northern part of the country. The objective of the study there-fore, is to examine the consequences of the trun-cated zoning arrangement and lessons from the Buhari Political tsunami in 2015 general elections in Nigeria, with interest on how to resolve such con-flicts that emanated. The study made use of qualita-tive research and the review of previous literature as sources of data collection. The findings revealed that, many people were killed during the years 2011-2015 under study; both private and public properties were also destroyed. This study recom-mends constitutional approach regarding the zoning formula to accom-modate all the six geopolitical zones in Nigeria in order to resolve the conflicts therein.

Thermally actuated linkage arrangement

International Nuclear Information System (INIS)

Anderson, P.M.

1981-01-01

A reusable thermally actuated linkage arrangement includes a first link member having a longitudinal bore therein adapted to receive at least a portion of a second link member therein, the first and second members being sized to effect an interference fit preventing relative movement there-between at a temperature below a predetermined temperature. The link members have different coefficients of thermal expansion so that when the linkage is selectively heated by heating element to a temperature above the predetermined temperature, relative longitudinal and/or rotational movement between the first and second link members is enabled. Two embodiments of a thermally activated linkage are disclosed which find particular application in actuators for a grapple head positioning arm in a nuclear reactor fuel handling mechanism to facilitate back-up safety retraction of the grapple head independently from the primary fuel handling mechanism drive system. (author)

Work-life balance and the legal right to request flexible working arrangements

Directory of Open Access Journals (Sweden)

L Dancaster

2014-07-01

Full Text Available In 2003, eligible employees in the United Kingdom acquired the legal right to request flexible working arrangements. The government believes that this new right will provide parents with greater choice and support in balancing work and childcare, whilst being compatible with business efficiency. This article critically appraises this new right and examines how it is applied in relation to other UK legislation on discrimination and unfair dismissal. An overview of international studies on corporate efforts to introduce family-friendly arrangements, and an overview of governmental efforts to address the reconciliation of work and family-life is provided in this article, with a view to arguing that there is a need, in South Africa, for state policy regarding work-life balance and for further research into corporate efforts to introduce family-friendly work arrangements.

Engine Power Turbine and Propulsion Pod Arrangement Study

Science.gov (United States)

Robuck, Mark; Zhang, Yiyi

2014-01-01

A study has been conducted for NASA Glenn Research Center under contract NNC10BA05B, Task NNC11TA80T to identify beneficial arrangements of the turboshaft engine, transmissions and related systems within the propulsion pod nacelle of NASA's Large Civil Tilt-Rotor 2nd iteration (LCTR2) vehicle. Propulsion pod layouts were used to investigate potential advantages, disadvantages, as well as constraints of various arrangements assuming front or aft shafted engines. Results from previous NASA LCTR2 propulsion system studies and tasks performed by Boeing under NASA contracts are used as the basis for this study. This configuration consists of two Fixed Geometry Variable Speed Power Turbine Engines and related drive and rotor systems (per nacelle) arranged in tilting nacelles near the wing tip. Entry-into-service (EIS) 2035 technology is assumed for both the engine and drive systems. The variable speed rotor system changes from 100 percent speed for hover to 54 percent speed for cruise by the means of a two speed gearbox concept developed under previous NASA contracts. Propulsion and drive system configurations that resulted in minimum vehicle gross weight were identified in previous work and used here. Results reported in this study illustrate that a forward shafted engine has a slight weight benefit over an aft shafted engine for the LCTR2 vehicle. Although the aft shafted engines provide a more controlled and centered CG (between hover and cruise), the length of the long rotor shaft and complicated engine exhaust arrangement outweighed the potential benefits. A Multi-Disciplinary Analysis and Optimization (MDAO) approach for transmission sizing was also explored for this study. This tool offers quick analysis of gear loads, bearing lives, efficiencies, etc., through use of commercially available RomaxDESIGNER software. The goal was to create quick methods to explore various concept models. The output results from RomaxDESIGNER have been successfully linked to Boeing

Phytoremediation of Pb and Hg by using Scirpus mucronatus with addition of bacterial inoculums

International Nuclear Information System (INIS)

Hamzah, A.; Yatim, N.I.; Sarmani, S.B.

2015-01-01

Two heavy metal-resistant rhizobacteria bacteria (Brevundimonas diminuta SF-S1-5 and Alcaligenes faecalis SF-S1-60) were bioaugmented in sand and also spiked with 100 ppm Pb and 1 ppm Hg and the removal of these metals was monitored using plant, Scirpus mucronatus. The highest accumulation of Pb and Hg were obtained in the root of S. mucronatus inoculated with A. faecalis at day 42 and 28, respectively. Plant inoculated with A. faecalis also showed the highest bioaccumulation coefficient and bioconcentration factor values > 1 compared to plant inoculated with B. diminuta and control. (author)

The effect of alternative work arrangements on women's well-being: a demand-control model.

Science.gov (United States)

Kelloway, E K; Gottlieb, B H

1998-01-01

The growth of women's participation in the labor force and evidence of the conflict they experience between job and family demands have spurred many employers to introduce alternative work arrangements such as flextime, job sharing, and telecommuting. Drawing on data gained from a sample of women (N = 998) in two large Canadian organizations, this study evaluates two mediational models of the impact of alternative work arrangements on women's stress and family role competence. Specifically, it tests and finds support for the hypotheses that (a) work arrangements involving scheduling flexibility (telecommuting and flextime) promote these aspects of women's well-being by increasing their perceived control over their time, and (b) arrangements involving reduced hours of employment (part-time employment and job sharing) promote well-being by reducing perceived job overload. Discussion of these findings centers on their implications for employed women, their employers, and future research.

The impact of a discrepancy between actual and preferred living arrangements on life satisfaction among the elderly in China.

Science.gov (United States)

Guan, Jinqun; Li, Hui; Sun, Hong; Wang, Ting; Wu, Weiping

2015-09-01

To explore the effects of a discrepancy between actual and preferred living arrangements on the relationship between living arrangements and life satisfaction among the elderly in China. Secondary analysis of the 2005 dataset of the Chinese Longitudinal Healthy Longevity Survey was performed. A binary logistic regression model was used to analyze the relationship between life satisfaction and living arrangements. Among those with concordant actual and preferred living arrangements, living in a nursing home increased the likelihood of life satisfaction, whereas living alone and living with a spouse decreased the likelihood of life satisfaction compared to living with the next generation and a spouse. Among those with discordant living arrangements, there were no differences in life satisfaction between the various living arrangements, except that living with a spouse increased life satisfaction compared to living with the next generation and a spouse. A discrepancy between actual and preferred living arrangements modifies the relationship between life satisfaction and actual living arrangement. Living in a nursing home is a good option for Chinese elder care only if the older individual emotionally accepts it. Living alone or with a spouse is not a good arrangement for elder care, even though it is often preferred by the elderly. Those with discordant living arrangements are more satisfied living with their spouses.

Clusters of ancestrally related genes that show paralogy in whole or in part are a major feature of the genomes of humans and other species.

Directory of Open Access Journals (Sweden)

Michael B Walker

Full Text Available Arrangements of genes along chromosomes are a product of evolutionary processes, and we can expect that preferable arrangements will prevail over the span of evolutionary time, often being reflected in the non-random clustering of structurally and/or functionally related genes. Such non-random arrangements can arise by two distinct evolutionary processes: duplications of DNA sequences that give rise to clusters of genes sharing both sequence similarity and common sequence features and the migration together of genes related by function, but not by common descent. To provide a background for distinguishing between the two, which is important for future efforts to unravel the evolutionary processes involved, we here provide a description of the extent to which ancestrally related genes are found in proximity.Towards this purpose, we combined information from five genomic datasets, InterPro, SCOP, PANTHER, Ensembl protein families, and Ensembl gene paralogs. The results are provided in publicly available datasets (http://cgd.jax.org/datasets/clustering/paraclustering.shtml describing the extent to which ancestrally related genes are in proximity beyond what is expected by chance (i.e. form paraclusters in the human and nine other vertebrate genomes, as well as the D. melanogaster, C. elegans, A. thaliana, and S. cerevisiae genomes. With the exception of Saccharomyces, paraclusters are a common feature of the genomes we examined. In the human genome they are estimated to include at least 22% of all protein coding genes. Paraclusters are far more prevalent among some gene families than others, are highly species or clade specific and can evolve rapidly, sometimes in response to environmental cues. Altogether, they account for a large portion of the functional clustering previously reported in several genomes.

Evolution of Land Rental Arrangements in Rural Ghana: Evidence ...

African Journals Online (AJOL)

zones of Ghana, their varied characters, trends of evolution, and the driving forces .... arrangements have not been given the needed attention in policy, perhaps due to ... markets follows a five-stage trajectory, which can broadly be divided into.

Problems of sanitary-hygienic arrangements in case of emergency situations

International Nuclear Information System (INIS)

Avetisov, G.M.; Borisov, B.K.; Volkov, N.N.; Grachev, M.I.; Korostin, A.S.; Prostakishin, G.P.

1995-01-01

The planning and carrying out sanitary-hygienic arrangements in emergency situation are based on scientific-research, organizing-methodical and practical trends of activities including: the necessity of taking into consideration the risk of sanitary-hygienic complications as a result of emergency situation; elaboration of criteria and classification of hazards potential danger of industrial plants and territories; the establishment of system of providing sanitary-hygienic measures in emergency situation; working out prophylactic measures for prevention, localization and liquidation of sanitary-hygienic after-effects of emergency situation; development of the system of control and express-analysis of hazardous factors; elaboration of rating-methodical base and arrangements aimed at protection of health and life of people. 5 refs

Importance of Grid Center Arrangement

Science.gov (United States)

Pasaogullari, O.; Usul, N.

2012-12-01

In Digital Elevation Modeling, grid size is accepted to be the most important parameter. Despite the point density and/or scale of the source data, it is freely decided by the user. Most of the time, arrangement of the grid centers are ignored, even most GIS packages omit the choice of grid center coordinate selection. In our study; importance of the arrangement of grid centers is investigated. Using the analogy between "Raster Grid DEM" and "Bitmap Image", importance of placement of grid centers in DEMs are measured. The study has been conducted on four different grid DEMs obtained from a half ellipsoid. These grid DEMs are obtained in such a way that they are half grid size apart from each other. Resulting grid DEMs are investigated through similarity measures. Image processing scientists use different measures to investigate the dis/similarity between the images and the amount of different information they carry. Grid DEMs are projected to a finer grid in order to co-center. Similarity measures are then applied to each grid DEM pairs. These similarity measures are adapted to DEM with band reduction and real number operation. One of the measures gives function graph and the others give measure matrices. Application of similarity measures to six grid DEM pairs shows interesting results. These four different grid DEMs are created with the same method for the same area, surprisingly; thirteen out of 14 measures state that, the half grid size apart grid DEMs are different from each other. The results indicated that although grid DEMs carry mutual information, they have also additional individual information. In other words, half grid size apart constructed grid DEMs have non-redundant information.; Joint Probability Distributions Function Graphs

The Staphylococcus aureus Two-Component System AgrAC Displays Four Distinct Genomic Arrangements That Delineate Genomic Virulence Factor Signatures

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Kumari S. Choudhary

2018-05-01

Full Text Available Two-component systems (TCSs consist of a histidine kinase and a response regulator. Here, we evaluated the conservation of the AgrAC TCS among 149 completely sequenced Staphylococcus aureus strains. It is composed of four genes: agrBDCA. We found that: (i AgrAC system (agr was found in all but one of the 149 strains, (ii the agr positive strains were further classified into four agr types based on AgrD protein sequences, (iii the four agr types not only specified the chromosomal arrangement of the agr genes but also the sequence divergence of AgrC histidine kinase protein, which confers signal specificity, (iv the sequence divergence was reflected in distinct structural properties especially in the transmembrane region and second extracellular binding domain, and (v there was a strong correlation between the agr type and the virulence genomic profile of the organism. Taken together, these results demonstrate that bioinformatic analysis of the agr locus leads to a classification system that correlates with the presence of virulence factors and protein structural properties.

The Staphylococcus aureus Two-Component System AgrAC Displays Four Distinct Genomic Arrangements That Delineate Genomic Virulence Factor Signatures

Science.gov (United States)

Choudhary, Kumari S.; Mih, Nathan; Monk, Jonathan; Kavvas, Erol; Yurkovich, James T.; Sakoulas, George; Palsson, Bernhard O.

2018-01-01

Two-component systems (TCSs) consist of a histidine kinase and a response regulator. Here, we evaluated the conservation of the AgrAC TCS among 149 completely sequenced Staphylococcus aureus strains. It is composed of four genes: agrBDCA. We found that: (i) AgrAC system (agr) was found in all but one of the 149 strains, (ii) the agr positive strains were further classified into four agr types based on AgrD protein sequences, (iii) the four agr types not only specified the chromosomal arrangement of the agr genes but also the sequence divergence of AgrC histidine kinase protein, which confers signal specificity, (iv) the sequence divergence was reflected in distinct structural properties especially in the transmembrane region and second extracellular binding domain, and (v) there was a strong correlation between the agr type and the virulence genomic profile of the organism. Taken together, these results demonstrate that bioinformatic analysis of the agr locus leads to a classification system that correlates with the presence of virulence factors and protein structural properties. PMID:29887846

CASTOR BEAN AND SUNFLOWER INTERCROPPING SYSTEMS IN ROW ARRANGEMENT: BIOLOGICAL EFFICIENCY

Directory of Open Access Journals (Sweden)

Ciro de Miranda Pinto

2012-07-01

Full Text Available An experiment field was carried in the agricultural seasons 2008, 2009 and 2010, with aim of studying the response of castorbean (Ricinus communis L. intercropping with sunflower (Helianthus annus L. in row arrangement in the dryland farming conditions. In addition, it was evaluated the biological efficiency of plants in intercropping systems.The design used in the experiment was randomized block with seven treatement and four replications. The treatments were represented by rows of castor oil (Ma and sunflower (Gi listed below: 1Ma:1Gi; 1Ma:2Gi; 1Ma:3Gi; 2Ma:2Gi; 2Ma:3Gi; castor and sunflower in the monoculture. The efficiency of intercropping was measured by LER, ATER, LEC, average between LER and ATER, SPI and CoR. The grain yield of castor bean and sunflower were reduced in intercropped row arrangements. The row arrangement 1Ma:2Gi showed the smallest reduction of average productivity of castor beans and sunflower in the evaluation period of the experiment. The castor bean was the dominant crop in relation to sunflower.

Consequences of Teen Parents’ Child Care Arrangements for Mothers and Children*

Science.gov (United States)

Mollborn, Stefanie; Blalock, Casey

2013-01-01

Using the nationally representative Early Childhood Longitudinal Study-Birth Cohort (2001 - 2006; N ≈ 7900), we examined child care arrangements among teen parents from birth through prekindergarten. Four latent classes of child care arrangements at 9, 24, and 52 months emerged: “parental care,” “center care,” “paid home-based care,” and “free kin-based care.” Disadvantaged teen-parent families were overrepresented in the “parental care” class, which was negatively associated with children’s preschool reading, math, and behavior scores and mothers’ socioeconomic and fertility outcomes compared to some nonparental care classes. Nonparental care did not predict any negative maternal or child outcomes, and different care arrangements had different benefits for mothers and children. Time spent in nonparental care and improved maternal outcomes contributed to children’s increased scores across domains. Child care classes predicted maternal outcomes similarly in teen-parent and nonteen-parent families, but the “parental care” class predicted some disproportionately negative child outcomes for teen-parent families. PMID:23729861

Parental survival, living arrangements and school enrolment of ...

African Journals Online (AJOL)

Parental survival, living arrangements and school enrolment of children in Malawi in the era of HIV/AIDS. ... findings are consistent with results from other countries that are hit hard by the AIDS epidemic and point to the critical role of the extended family system in taking care of the disadvantaged and vulnerable children.

Flexible Work Arrangements: Accessibility in a University Environment

Science.gov (United States)

Sharafizad, Fleur; Paull, Megan; Omari, Maryam

2011-01-01

Attraction and retention of highly qualified employees has become an area of concern for Australian universities. It has been suggested that flexible work arrangements can be utilised to achieve this goal once the factors affecting their uptake have been identified. This mixed-method study of 495 academic and general staff at an Australian…

Development of the APR+ Auxiliary Building General Arrangement (GA)

International Nuclear Information System (INIS)

Moon, Hyung Keun; Park, Young Sheop; Kang, Yong Chul

2011-01-01

The general arrangement (GA) drawing of a nuclear power plant is the most basic drawing which contains all of the plant equipment, systems, and rooms. Therefore, it should be issued at an early design stage to provide the contours of the overall plant structure. This type of drawing is typically used widely throughout the design stages. The development project of APR+ (Advanced Power Reactor+), as a succeeding model of the APR1400 (Advanced Power Reactor 1400) design, has its own GA that encompasses all of its power buildings. This was developed starting in October of 2009. Among several of the buildings in this design, the Auxiliary Building (AB) is one of the most important buildings to produce electricity, and to protect against undesirable radiation emissions. This paper focuses on the design characteristics of the general arrangement of the AB

Effect of beam arrangement on oral cavity dose in external beam radiotherapy of nasopharyngeal carcinoma

International Nuclear Information System (INIS)

Wu, Vincent W.C.; Yang Zhining; Zhang Wuzhe; Wu Lili; Lin Zhixiong

2012-01-01

This study compared the oral cavity dose between the routine 7-beam intensity-modulated radiotherapy (IMRT) beam arrangement and 2 other 7-beam IMRT with the conventional radiotherapy beam arrangements in the treatment of nasopharyngeal carcinoma (NPC). Ten NPC patients treated by the 7-beam routine IMRT technique (IMRT-7R) between April 2009 and June 2009 were recruited. Using the same computed tomography data, target information, and dose constraints for all the contoured structures, 2 IMRT plans with alternative beam arrangements (IMRT-7M and IMRT-7P) by avoiding the anterior facial beam and 1 conventional radiotherapy plan (CONRT) were computed using the Pinnacle treatment planning system. Dose-volume histograms were generated for the planning target volumes (PTVs) and oral cavity from which the dose parameters and the conformity index of the PTV were recorded for dosimetric comparisons among the plans with different beam arrangements. The dose distributions to the PTVs were similar among the 3 IMRT beam arrangements, whereas the differences were significant between IMRT-7R and CONRT plans. For the oral cavity dose, the 3 IMRT beam arrangements did not show significant difference. Compared with IMRT-7R, CONRT plan showed a significantly lower mean dose, V30 and V-40, whereas the V-60 was significantly higher. The 2 suggested alternative beam arrangements did not significantly reduce the oral cavity dose. The impact of varying the beam angles in IMRT of NPC did not give noticeable effect on the target and oral cavity. Compared with IMRT, the 2-D conventional radiotherapy irradiated a greater high-dose volume in the oral cavity.

Studies on optimal design and operation of integrated distillation arrangements

Energy Technology Data Exchange (ETDEWEB)

Christiansen, Atle Christer

1997-12-31

During the last decades, there has been growing concern in the chemical engineering environment over the task of developing more cost- and energy efficient process equipment. This thesis discusses measures for improving the end-use energy efficiency of separation systems. It emphasises a certain class of integrated distillation arrangements, in particular it considers means for direct coupling of distillation columns so as to use the underlying physics to facilitate more energy efficient separations. The numerical methods discussed are well suited to solve models of distillation columns. A tear and grid method is proposed that to some extent exploits the sparsity, since the number of tear variables required for solving a distillation model usually is rather small. The parameter continuation method described is well suited for ill-conditioned problems. The analysis of integrated columns is extended beyond the scope of numerical simulations by means of analytical results that applies in certain limiting cases. The consept of preferred separation, which is important for prefractionator arrangements, is considered. From this analysis is derived information that is important for the practical operation of such columns. Finally, the proposed numerical methods are used to optimize Petlyuk arrangements for separating ternary and quaternary mixtures. 166 refs., 130 figs., 20 tabs.

Children's postdivorce residence arrangements and parental experienced time pressure

NARCIS (Netherlands)

van der Heijden, Franciëlla; Poortman, Anne Rigt; van der Lippe, Tanja

2016-01-01

Although the rise in postdivorce joint physical custody has fueled scholarly interest in its impact on children, consequences for parents remain understudied. Because children's residence arrangements determine time and coordination demands associated with child care, this study investigated the

Triangularly arranged heat exchanger bundles to restrain wind effects on natural draft dry cooling system

International Nuclear Information System (INIS)

Liao, H.T.; Yang, L.J.; Du, X.Z.; Yang, Y.P.

2016-01-01

Highlights: • Triangularly arranged heat exchanger around the dry-cooling tower is proposed. • By coupling condenser with dry cooling system, TACHE performance is obtained. • At low wind speeds, cooling performance with TACHE is inferior to that with CACHE. • Better performance can be achieved for cooling system with TACHE at high wind speeds. • TACHE can be applied to the region with the strong prevailing wind all year around. - Abstract: It has been commonly recognized that the crosswind may deteriorate the cooling performance of the natural draft dry cooling system with vertically arranged heat exchanger bundles around the circumference of dry-cooling tower. With the purpose for restraining the adverse effects of ambient winds, a novel triangular configuration of heat exchanger bundles is proposed in this work. The air-side flow and heat transfer models coupled with the circulating water heat transfer process are developed for two kinds of natural draft dry cooling systems with the conventional circularly arranged and novel triangularly arranged heat exchanger bundles, by which the flow and temperature fields, mass flow rate of cooling air, outlet water temperature of heat exchanger and turbine back pressure are obtained. Three wind directions of 0°, 90°, and 180° are investigated at various wind speeds for the natural draft dry cooling system with triangularly arranged heat exchanger bundles, which are compared with the conventional system with circularly arranged heat exchanger bundles. The results show that the thermo-flow performances of the natural draft dry cooling system with triangularly arranged heat exchanger get improved significantly at high wind speeds and in the wind direction of 180°, thus a low turbine back pressure can be achieved, which is of benefit to the energy efficiency of the power generating unit. The natural draft dry cooling system with triangularly arranged heat exchanger is recommended to apply to the regions with

Genetic and epigenetic variation in 5S ribosomal RNA genes reveals genome dynamics in Arabidopsis thaliana.

Science.gov (United States)

Simon, Lauriane; Rabanal, Fernando A; Dubos, Tristan; Oliver, Cecilia; Lauber, Damien; Poulet, Axel; Vogt, Alexander; Mandlbauer, Ariane; Le Goff, Samuel; Sommer, Andreas; Duborjal, Hervé; Tatout, Christophe; Probst, Aline V

2018-04-06

Organized in tandem repeat arrays in most eukaryotes and transcribed by RNA polymerase III, expression of 5S rRNA genes is under epigenetic control. To unveil mechanisms of transcriptional regulation, we obtained here in depth sequence information on 5S rRNA genes from the Arabidopsis thaliana genome and identified differential enrichment in epigenetic marks between the three 5S rDNA loci situated on chromosomes 3, 4 and 5. We reveal the chromosome 5 locus as the major source of an atypical, long 5S rRNA transcript characteristic of an open chromatin structure. 5S rRNA genes from this locus translocated in the Landsberg erecta ecotype as shown by linkage mapping and chromosome-specific FISH analysis. These variations in 5S rDNA locus organization cause changes in the spatial arrangement of chromosomes in the nucleus. Furthermore, 5S rRNA gene arrangements are highly dynamic with alterations in chromosomal positions through translocations in certain mutants of the RNA-directed DNA methylation pathway and important copy number variations among ecotypes. Finally, variations in 5S rRNA gene sequence, chromatin organization and transcripts indicate differential usage of 5S rDNA loci in distinct ecotypes. We suggest that both the usage of existing and new 5S rDNA loci resulting from translocations may impact neighboring chromatin organization.

48 CFR 1.105-2 - Arrangement of regulations.

Science.gov (United States)

2010-10-01

... GENERAL FEDERAL ACQUISITION REGULATIONS SYSTEM Purpose, Authority, Issuance 1.105-2 Arrangement of..., represent, in order, the subpart (one or two digits), and the section (two digits). The number to the right...)” outside the FAR and “9.106-4(d)” within the FAR. (4) Citations of authority (e.g., statutes or executive...

Sleeping Out of Home in a Kibbutz Communal Arrangement: It Makes a Difference for Infant-Mother Attachment.

Science.gov (United States)

Sagi, Abraham; And Others

1994-01-01

Compared the attachment classification distributions of 23 infants in Israeli kibbutzim with communal sleeping arrangements with those of 25 infants in kibbutzim with home-based sleeping arrangements. Among the home-based infants, 80% were securely attached to their mothers versus only 48% of the infants in communal sleeping arrangements. (MDM)

Mitochondrial genomes of Meloidogyne chitwoodi and M. incognita (Nematoda: Tylenchina): comparative analysis, gene order and phylogenetic relationships with other nematodes.

Science.gov (United States)

Humphreys-Pereira, Danny A; Elling, Axel A

2014-01-01

Root-knot nematodes (Meloidogyne spp.) are among the most important plant pathogens. In this study, the mitochondrial (mt) genomes of the root-knot nematodes, M. chitwoodi and M. incognita were sequenced. PCR analyses suggest that both mt genomes are circular, with an estimated size of 19.7 and 18.6-19.1kb, respectively. The mt genomes each contain a large non-coding region with tandem repeats and the control region. The mt gene arrangement of M. chitwoodi and M. incognita is unlike that of other nematodes. Sequence alignments of the two Meloidogyne mt genomes showed three translocations; two in transfer RNAs and one in cox2. Compared with other nematode mt genomes, the gene arrangement of M. chitwoodi and M. incognita was most similar to Pratylenchus vulnus. Phylogenetic analyses (Maximum Likelihood and Bayesian inference) were conducted using 78 complete mt genomes of diverse nematode species. Analyses based on nucleotides and amino acids of the 12 protein-coding mt genes showed strong support for the monophyly of class Chromadorea, but only amino acid-based analyses supported the monophyly of class Enoplea. The suborder Spirurina was not monophyletic in any of the phylogenetic analyses, contradicting the Clade III model, which groups Ascaridomorpha, Spiruromorpha and Oxyuridomorpha based on the small subunit ribosomal RNA gene. Importantly, comparisons of mt gene arrangement and tree-based methods placed Meloidogyne as sister taxa of Pratylenchus, a migratory plant endoparasitic nematode, and not with the sedentary endoparasitic Heterodera. Thus, comparative analyses of mt genomes suggest that sedentary endoparasitism in Meloidogyne and Heterodera is based on convergent evolution. Copyright © 2014 Elsevier B.V. All rights reserved.

The impact of a discrepancy between actual and preferred living arrangements on life satisfaction among the elderly in China

Directory of Open Access Journals (Sweden)

Jinqun Guan

2015-09-01

Full Text Available OBJECTIVES: To explore the effects of a discrepancy between actual and preferred living arrangements on the relationship between living arrangements and life satisfaction among the elderly in China. METHODS: Secondary analysis of the 2005 dataset of the Chinese Longitudinal Healthy Longevity Survey was performed. A binary logistic regression model was used to analyze the relationship between life satisfaction and living arrangements. RESULTS: Among those with concordant actual and preferred living arrangements, living in a nursing home increased the likelihood of life satisfaction, whereas living alone and living with a spouse decreased the likelihood of life satisfaction compared to living with the next generation and a spouse. Among those with discordant living arrangements, there were no differences in life satisfaction between the various living arrangements, except that living with a spouse increased life satisfaction compared to living with the next generation and a spouse. CONCLUSIONS: A discrepancy between actual and preferred living arrangements modifies the relationship between life satisfaction and actual living arrangement. Living in a nursing home is a good option for Chinese elder care only if the older individual emotionally accepts it. Living alone or with a spouse is not a good arrangement for elder care, even though it is often preferred by the elderly. Those with discordant living arrangements are more satisfied living with their spouses.

Field arrangement and dosimetry verification for concave target

International Nuclear Information System (INIS)

Chen Liang; Wang Huankun; Li Yumin

2005-01-01

Objective: To provide a method of radiotherapy field arrangement for concave paraspinal target. Methods: Plan was designed for concave target in wax phantom and the selected patients by the guidance of beam eye view (BEV) provided by a 3D treatment planning system (CREAT EXPERT). In BEV, the inner border of all tangential fields was 2 mm out of the organ at risk (OAR) and the outer border was 5 mm beyond the target. Dosimetry films and ion chamber were used to verify the dose distribution and point dose in the wax phantom. Results: Dose distribution in phantom and patient was homogeneous. The mean dose of OAR in phantom did not exceed 16% of the prescribed dose. Isodose curves dropped more than 8% per mm between the target and OAR in the phantom. Film dosimetry coincided well with the calculated results. Position error in high dose region was with- in 4 mm and absolute dose errors were no more than 5%. Conclusion: Tangential field arrangement is valuable and practical in radiotherapy for concave paraspinal targets. (authors)

Liposomes for Use in Gene Delivery

Directory of Open Access Journals (Sweden)

Daniel A. Balazs

2011-01-01

Full Text Available Liposomes have a wide array of uses that have been continuously expanded and improved upon since first being observed to self-assemble into vesicular structures. These arrangements can be found in many shapes and sizes depending on lipid composition. Liposomes are often used to deliver a molecular cargo such as DNA for therapeutic benefit. The lipids used to form such lipoplexes can be cationic, anionic, neutral, or a mixture thereof. Herein physical packing parameters and specific lipids used for gene delivery will be discussed, with lipids classified according to overall charge.

Distribution of essential medicines to primary care institutions in Hubei of China: effects of centralized procurement arrangements.

Science.gov (United States)

Yang, Lianping; Huang, Cunrui; Liu, Chaojie

2017-11-14

Poor distribution of essential medicines to primary care institutions has attracted criticism since China adopted provincial centralized regional tendering and procurement systems. This study evaluated the impact of new procurement arrangements that limit the number of distributors at the county level in Hubei province, China. Procurement ordering and distribution data were collected from four counties that pioneered a new distribution arrangement (commencing September 2012) compared with six counties that continued the existing arrangement over the period from August 2011 to September 2013. The new arrangement allowed primary care institutions and/or suppliers to select a local distributor from a limited panel (from 3 to 5) of government nominated distributors. Difference-in-differences analyses were performed to assess the impact of the new arrangements on delivery and receipt of essential medicines. Overall, the new distribution arrangement has not improved distribution of essential medicines to primary care institutions. On the contrary, we found a 7.78-19.85 percentage point (p Procurement arrangements need to consider the special characteristics of rural facilities. In a county, there are more rural primary care institutions than urban ones. On average, rural primary care institutions demand more and are more geographically dispersed compared to their urban counterparts, which may impose increased distribution costs.

Minimum Energy Requirements in Complex Distillation Arrangements

Energy Technology Data Exchange (ETDEWEB)

Halvorsen, Ivar J

2001-07-01

Distillation is the most widely used industrial separation technology and distillation units are responsible for a significant part of the total heat consumption in the world's process industry. In this work we focus on directly (fully thermally) coupled column arrangements for separation of multicomponent mixtures. These systems are also denoted Petlyuk arrangements, where a particular implementation is the dividing wall column. Energy savings in the range of 20-40% have been reported with ternary feed mixtures. In addition to energy savings, such integrated units have also a potential for reduced capital cost, making them extra attractive. However, the industrial use has been limited, and difficulties in design and control have been reported as the main reasons. Minimum energy results have only been available for ternary feed mixtures and sharp product splits. This motivates further research in this area, and this thesis will hopefully give some contributions to better understanding of complex column systems. In the first part we derive the general analytic solution for minimum energy consumption in directly coupled columns for a multicomponent feed and any number of products. To our knowledge, this is a new contribution in the field. The basic assumptions are constant relative volatility, constant pressure and constant molar flows and the derivation is based on Underwood's classical methods. An important conclusion is that the minimum energy consumption in a complex directly integrated multi-product arrangement is the same as for the most difficult split between any pair of the specified products when we consider the performance of a conventional two-product column. We also present the Vmin-diagram, which is a simple graphical tool for visualisation of minimum energy related to feed distribution. The Vmin-diagram provides a simple mean to assess the detailed flow requirements for all parts of a complex directly coupled arrangement. The main purpose in the first

Minimum Energy Requirements in Complex Distillation Arrangements

Energy Technology Data Exchange (ETDEWEB)

Halvorsen, Ivar J.

2001-07-01

Distillation is the most widely used industrial separation technology and distillation units are responsible for a significant part of the total heat consumption in the world's process industry. In this work we focus on directly (fully thermally) coupled column arrangements for separation of multicomponent mixtures. These systems are also denoted Petlyuk arrangements, where a particular implementation is the dividing wall column. Energy savings in the range of 20-40% have been reported with ternary feed mixtures. In addition to energy savings, such integrated units have also a potential for reduced capital cost, making them extra attractive. However, the industrial use has been limited, and difficulties in design and control have been reported as the main reasons. Minimum energy results have only been available for ternary feed mixtures and sharp product splits. This motivates further research in this area, and this thesis will hopefully give some contributions to better understanding of complex column systems. In the first part we derive the general analytic solution for minimum energy consumption in directly coupled columns for a multicomponent feed and any number of products. To our knowledge, this is a new contribution in the field. The basic assumptions are constant relative volatility, constant pressure and constant molar flows and the derivation is based on Underwood's classical methods. An important conclusion is that the minimum energy consumption in a complex directly integrated multi-product arrangement is the same as for the most difficult split between any pair of the specified products when we consider the performance of a conventional two-product column. We also present the Vmin-diagram, which is a simple graphical tool for visualisation of minimum energy related to feed distribution. The Vmin-diagram provides a simple mean to assess the detailed flow requirements for all parts of a complex directly coupled arrangement. The main purpose in

Prediction of operon-like gene clusters in the Arabidopsis thaliana genome based on co-expression analysis of neighboring genes.

Science.gov (United States)

Wada, Masayoshi; Takahashi, Hiroki; Altaf-Ul-Amin, Md; Nakamura, Kensuke; Hirai, Masami Y; Ohta, Daisaku; Kanaya, Shigehiko

2012-07-15

Operon-like arrangements of genes occur in eukaryotes ranging from yeasts and filamentous fungi to nematodes, plants, and mammals. In plants, several examples of operon-like gene clusters involved in metabolic pathways have recently been characterized, e.g. the cyclic hydroxamic acid pathways in maize, the avenacin biosynthesis gene clusters in oat, the thalianol pathway in Arabidopsis thaliana, and the diterpenoid momilactone cluster in rice. Such operon-like gene clusters are defined by their co-regulation or neighboring positions within immediate vicinity of chromosomal regions. A comprehensive analysis of the expression of neighboring genes therefore accounts a crucial step to reveal the complete set of operon-like gene clusters within a genome. Genome-wide prediction of operon-like gene clusters should contribute to functional annotation efforts and provide novel insight into evolutionary aspects acquiring certain biological functions as well. We predicted co-expressed gene clusters by comparing the Pearson correlation coefficient of neighboring genes and randomly selected gene pairs, based on a statistical method that takes false discovery rate (FDR) into consideration for 1469 microarray gene expression datasets of A. thaliana. We estimated that A. thaliana contains 100 operon-like gene clusters in total. We predicted 34 statistically significant gene clusters consisting of 3 to 22 genes each, based on a stringent FDR threshold of 0.1. Functional relationships among genes in individual clusters were estimated by sequence similarity and functional annotation of genes. Duplicated gene pairs (determined based on BLAST with a cutoff of EOperon-like clusters tend to include genes encoding bio-machinery associated with ribosomes, the ubiquitin/proteasome system, secondary metabolic pathways, lipid and fatty-acid metabolism, and the lipid transfer system. Copyright © 2012 Elsevier B.V. All rights reserved.

The Dynamics of Decentralization Arrangements in Indonesia Constitutional System

Directory of Open Access Journals (Sweden)

Haposan Siallagan

2016-06-01

Full Text Available Local autonomy has long been implemented in Indonesia and has been experiencing a number of phases within governmental system. This writing is intended to fathom the dynamics of decentralization arrangement indeed. The discussion it-self shows that according to the substances in a number of decentralization policy which had/has been issued, the dynamics of local autonomy arrangements (as regulated in many decentralization policies are inclining to be captured in a broad meaning, which is frequently known as a broadest local autonomy. Through local autonomy mechanism, local governments are given a flexibility in order to manage and administer their own domestic household. In order to maximize the implementation of widest local autonomy, local government has to be pushed to be well prepared in handling many local governmental tasks. Such preparations are related to human resources capacity, the competences in running the tasks, and financial management capacity.

INNOVATION IN BRAZILIAN TERRITORIAL ASSOCIATION: THE EDUCATIONAL DEVELOPMENT ARRANGEMENTS

Directory of Open Access Journals (Sweden)

Eduardo José Grin

2017-09-01

Full Text Available The article analyzes the Development Educational Arrangements as ways of territorial association which, in Brasil, since the 2000s, have been one more alternative for municipal consortia. The object of analysis is formed by two cases: the Corredor da Vale (Maranhão and the Chapada Diamantina (Bahia. The research was implemented based on secondary data and a field investigation that interviewed educational municipal managers and representatives from state governments. The selected cases were based on the diverse case methodology that analyzes, controlling variables, different effects of independent variable over dependent variable. The central argument tested is that Educational Arrangements are the independent variables that produce effect on educational territorial governance like dependent variable. We concluded that the larger success in baiano case it was due to factor like regional leadership, social control, path and context of its construction, what didn't happen in the maranhense case.

Stereo photograph of atomic arrangement by circularly-polarized-light two-dimensional photoelectron spectroscopy

International Nuclear Information System (INIS)

Daimon, Hiroshi

2003-01-01

A stereo photograph of atomic arrangement was obtained for the first time. The stereo photograph was displayed directly on the screen of display-type spherical-mirror analyzer without any computer-aided conversion process. This stereo photography was realized taking advantage of the phenomenon of circular dichroism in photoelectron angular distribution due to the reversal of orbital angular momentum of photoelectrons. The azimuthal shifts of forward focusing peaks in a photoelectron angular distribution pattern taken with left and right helicity light in a special arrangement are the same as the parallaxes in a stereo view of atoms. Hence a stereoscopic recognition of three-dimensional atomic arrangement is possible, when the left eye and the right eye respectively view the two images obtained by left and right helicity light simultaneously. (author)

The enforcement order for the law for arrangement of surrounding areas of power generating facilities

International Nuclear Information System (INIS)

1984-01-01

The enforcement order provides for grants concerning the arrangement of various public facilities in the areas surrounding a power generating facility; the public facilities in the arrangement for which the grants are given include communication, recreation activities, environmental sanitation, culture, medicine, etc. The prefectural governor concerned submits his plan for the arrangement to the Government, which then decides on the grants. Then, the grants are given to local governments concerned. The sums of the grants are determined on the basis of the output, construction cost of the nuclear power facility. (Mori, K.)

Electricity transmission arrangements in Great Britain: Time for change?

International Nuclear Information System (INIS)

Strbac, Goran; Pollitt, Michael; Konstantinidis, Christos Vasilakos; Konstantelos, Ioannis; Moreno, Rodrigo; Newbery, David; Green, Richard

2014-01-01

In Great Britain (GB) and across Europe significant investment in electricity transmission is expected over the coming years as decarbonisation and market integration efforts are intensified. However, there is also significant uncertainty with the amount, location and timing of new generation connection, which in turn will drive the transmission investment needs. Given the absence of efficient market design, we identify three key areas of concern with the current transmission investment arrangements: (i) a mis-aligned incentives framework for transmission investment and operation; (ii) lack of coordination of investment and operation; and (iii) conflicts of interest. We then propose three options for future evolution of transmission regimes, which cover the full spectrum of institutional arrangements with respect to transmission planning and delivery, i.e. how and who plans, owns, builds and operates the transmission system. For each option we present: key characteristics; evolution of the current regimes; the ability of the option to address the concerns; and key strengths and weaknesses. Overall, we conclude in the case of GB (this conclusion could be extended to other European countries) that the most appropriate option would be that of an Independent System Operator (ISO) who would be responsible for planning and operating the transmission system. - Highlights: • We identify three key areas of concern with the current transmission arrangements. • We then propose three options for transmission network planning and delivery. • Key strengths and weaknesses of each above option are identified and studied. • We conclude that the most appropriate option for GB would be that of an ISO

Identifikasi dan Kuantifikasi Metabolit Bakteri Pelarut Fosfat dan Pengaruhnya terhadap Aktivitas Rhizoctonia solani pada Tanaman Kedelai

Directory of Open Access Journals (Sweden)

Tri Candra Setiawati

2008-09-01

Full Text Available Phosphate solubilizing bacteria (PSB metabolites are organic acids, phosphomonoesterase enzyme (alkaline phosphatase and antibiotic, which is able to dissolve insoluble phosphate. Phosphate solubilizing bacteria used in this study was expected to suppress Rhizoctonia solani attacks. This experiment was aimed at (1 identifiying and quantifying PSB metabolites, and (2 examining their capability as biocontrol agent for Rhizoctonia solani in vitro and hydroponics soybean. This study was conducted in three stages. The first stage of this study was culturing two PSB isolates (Pseudomonas putida 27.4B and Pseudomonas diminuta in the Pikovskaya medium to analyze their metabolites. The second and third stage of this study was testing the antagonist of two bacteria to suppressed R. solani activity, which was conducted in vitro, and in hydroponics medium soybean as indicator plant. The results showed that P. putida 27.4B and P. diminuta produced organic acids i.e.: citrate, formic, succinic, acetic, propionate, butyrate, and oxalate. The totals of organic acids from each bacterium were 70,3 mg.kg-1 and 61,9 mg.kg-1. Production of alkaline phosphatase enzyme in Pikovskaya medium of P. Putida 27.4B was 11,71 ìg pNP .mL-1.h-1 and P. diminuta was 24,04 ìg pNP.mL-1.h-1. Concentration of this enzyme in soil medium was higher than that in Pikovskaya medium with 26,27 ìg pNP.g-1.h-1 and 39,03 ìg pNP.g-1.h-1 respectively. This study also showed that total concentration of antibiotics (tetracycline, oxitetracycline and penicillin produced by the PSB, were 3,2 ìg.mL-1 (P. putida 27.4B and 10,96 ìg.m1-1 (P. diminuta, respectively. The results from second stage of this study showed that by using in vitro, the reduced growth of R. solani was observed 58,35% with P. putida 27.4B and 41,96% with P. diminuta. In addition, inoculations of PSB in hydroponics medium reduced the fungal pathogenesis from 10,71% to 21,42% of pre and post emergence damping-off. Visually

Contracting for engineering services: Experience with innovative fee arrangements

International Nuclear Information System (INIS)

Criner, D.E.; Schenk, J.L.

1995-01-01

The relationship between an engineering firm and a client can be favorably influenced by a clearly defined incentive plan. This paper addresses several approaches and the advantages and disadvantages of each. It also summarizes the lessons learned to date in using incentive fee arrangements

48 CFR 1.105-1 - Publication and code arrangement.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Publication and code arrangement. 1.105-1 Section 1.105-1 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL FEDERAL ACQUISITION REGULATIONS SYSTEM Purpose, Authority, Issuance 1.105-1 Publication and code...

48 CFR 401.105-1 - Publication and code arrangement.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Publication and code arrangement. 401.105-1 Section 401.105-1 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE GENERAL AGRICULTURE ACQUISITION REGULATION SYSTEM Purpose, Authority, Issuance 401.105-1 Publication and...

A conceptual schema for government purchasing arrangements for Australian alcohol and other drug treatment.

Science.gov (United States)

Ritter, Alison; Hull, Philip; Berends, Lynda; Chalmers, Jenny; Lancaster, Kari

2016-09-01

The aim of this study was to establish a conceptual schema for government purchasing of alcohol and other drug treatment in Australia which could encompass the diversity and variety in purchasing arrangements, and facilitate better decision-maker by purchasers. There is a limited evidence base on purchasing arrangements in alcohol and drug treatment despite the clear impact of purchasing arrangements on both treatment processes and treatment outcomes. The relevant health and social welfare literature on purchasing arrangements was reviewed; data were collected from Australian purchasers and providers of treatment giving detailed descriptions of the array of purchasing arrangements. Combined analysis of the literature and the Australian purchasing data resulted in a draft schema which was then reviewed by an expert committee and subsequently finalised. The conceptual schema presented here was purpose-built for alcohol and other drug treatment, with its overlap between health and social welfare services. It has three dimensions: 1. The ways in which providers are chosen; 2. The ways in which services are paid for; and 3. How price is managed. Distinguishing between the methods for choosing providers (such as competitive or individually negotiated processes) from the way in which organisations are paid for their provision of treatment (such as via a block grant or payment for activity) provides conceptual clarity and enables closer analysis of each mechanism. Governments can improve health and wellbeing by making informed decisions about the way they purchase and fund alcohol and other drug treatment. Research comparing different purchasing arrangements can provide a vital evidence-base to inform funders; however a first step is to accurately and consistently categorise current approaches against a typology or conceptual schema. Copyright © 2016 Elsevier Ltd. All rights reserved.

22 CFR 102.9 - Arranging for entry and travel of investigating and airline representatives.

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Arranging for entry and travel of investigating and airline representatives. 102.9 Section 102.9 Foreign Relations DEPARTMENT OF STATE ECONOMIC AND OTHER FUNCTIONS CIVIL AVIATION United States Aircraft Accidents Abroad § 102.9 Arranging for entry and travel of investigating and airline...

Jet spoiler arrangement for wind turbine

Science.gov (United States)

Cyrus, J. D.; Kablec, E. G.; Klimas, P. C.

1983-09-01

An air jet spoiler arrangement is provided for a Darrieus-type vertical axis wind-powered turbine. Air is drawn into hollow turbine blades through air inlets at the end thereof and is ejected in the form of air jets through small holes or openings provided along the lengths of the blades. The air jets create flow separation at the surfaces of the turbine blades, thereby including stal conditions and reducing the output power. A feedback control unit senses the power output of the turbine and controls the amount of air drawn into the air inlets accordingly.

Jet spoiler arrangement for wind turbine

Science.gov (United States)

Cyrus, Jack D.; Kadlec, Emil G.; Klimas, Paul C.

1985-01-01

An air jet spoiler arrangement is provided for a Darrieus-type vertical axis wind-powered turbine. Air is drawn into hollow turbine blades through air inlets at the ends thereof and is ejected in the form of air jets through small holes or openings provided along the lengths of the blades. The air jets create flow separation at the surfaces of the turbine blades, thereby inducing stall conditions and reducing the output power. A feedback control unit senses the power output of the turbine and controls the amount of air drawn into the air inlets accordingly.

Coccolith arrangement follows Eulerian mathematics in the coccolithophore Emiliania huxleyi.

Science.gov (United States)

Xu, Kai; Hutchins, David; Gao, Kunshan

2018-01-01

The globally abundant coccolithophore, Emiliania huxleyi , plays an important ecological role in oceanic carbon biogeochemistry by forming a cellular covering of plate-like CaCO 3 crystals (coccoliths) and fixing CO 2 . It is unknown how the cells arrange different-sized coccoliths to maintain full coverage, as the cell surface area of the cell changes during daily cycle. We used Euler's polyhedron formula and CaGe simulation software, validated with the geometries of coccoliths, to analyze and simulate the coccolith topology of the coccosphere and to explore the arrangement mechanisms. There were only small variations in the geometries of coccoliths, even when the cells were cultured under variable light conditions. Because of geometric limits, small coccoliths tended to interlock with fewer and larger coccoliths, and vice versa. Consequently, to sustain a full coverage on the surface of cell, each coccolith was arranged to interlock with four to six others, which in turn led to each coccosphere contains at least six coccoliths. The number of coccoliths per coccosphere must keep pace with changes on the cell surface area as a result of photosynthesis, respiration and cell division. This study is an example of natural selection following Euler's polyhedral formula, in response to the challenge of maintaining a CaCO 3 covering on coccolithophore cells as cell size changes.

Coccolith arrangement follows Eulerian mathematics in the coccolithophore Emiliania huxleyi

Directory of Open Access Journals (Sweden)

Kai Xu

2018-04-01

Full Text Available Background The globally abundant coccolithophore, Emiliania huxleyi, plays an important ecological role in oceanic carbon biogeochemistry by forming a cellular covering of plate-like CaCO3 crystals (coccoliths and fixing CO2. It is unknown how the cells arrange different-sized coccoliths to maintain full coverage, as the cell surface area of the cell changes during daily cycle. Methods We used Euler’s polyhedron formula and CaGe simulation software, validated with the geometries of coccoliths, to analyze and simulate the coccolith topology of the coccosphere and to explore the arrangement mechanisms. Results There were only small variations in the geometries of coccoliths, even when the cells were cultured under variable light conditions. Because of geometric limits, small coccoliths tended to interlock with fewer and larger coccoliths, and vice versa. Consequently, to sustain a full coverage on the surface of cell, each coccolith was arranged to interlock with four to six others, which in turn led to each coccosphere contains at least six coccoliths. Conclusion The number of coccoliths per coccosphere must keep pace with changes on the cell surface area as a result of photosynthesis, respiration and cell division. This study is an example of natural selection following Euler’s polyhedral formula, in response to the challenge of maintaining a CaCO3 covering on coccolithophore cells as cell size changes.

Arrangement for matching a wind rotor to an electrical generator

Energy Technology Data Exchange (ETDEWEB)

Beusse, H

1978-04-06

The invention concerns an arrangement for matching a wind power machine to an electrical generator, which feeds a consumer network. According to the invention first generator using the shaft horsepower of the wind power machine feeds an electric water, which is coupled to a second generator, whose power is taken to the consumer network. The output signal of a computer which has the annemometer feeding into it controls the excitation of the motor at sufficient wind speed, so that the speed of rotation of the second generator is practically constant, and a spted regulator takes excess energy via a controlled rectifier (thyristor) to a shunt circuit of the motor, if the wind power exceeds the load taken from the output of the second generator. As an extension of the arrangement according to the invention it is proposed to arrange a Diesel engine in the shaft of the second generator, which can be controlled at constant speed by the control device, so that it takes over the missing output if the wind power is less than the load at the generator output. Apart from this, it is proposed that the loading of the wind rotor should be controlled by the control device so that it only comes in if the wind rotor has reached a stable working point after accelerating on no load.

New host, geographical records, and factors affecting the prevalence of helminths infection from synanthropic rodents in Yucatán, Mexico

Directory of Open Access Journals (Sweden)

Panti-May J. A.

2017-09-01

Full Text Available The aim of this paper was to study the occurrence of helminths in Mus musculus and Rattus rattus from urban, suburban and rural settlements in Yucatán, Mexico; and to analyse the host factors (e.g. sex related to helminths’ distribution. Helminths in a total of 279 rodents were surveyed by visual examination of the liver for metacestodes and faecal examination for helminth eggs using the formalin-ethyl acetate sedimentation technique. The cestodes Hydatigera taeniaeformis (metacestodes detected in the liver and Hymenolepis diminuta, and the nematodes Aspiculuris sp., Nippostrongylus brasiliensis, Syphacia muris, Syphacia obvelata, and Trichuris muris were identified. In M. musculus, the prevalence of infection with T. muris and H. taeniaeformis was higher in the rural village compared to those in the suburban neighbourhood. For R. rattus, a higher prevalence of infection with H. diminuta was found in the urban site compared to that in the suburban site. This study reports the occurrence of H. diminuta among rodents living in close proximity to humans, representing a potential public health risk. In addition, this survey increases our understanding of dynamic transmission among intestinal helminths recorded in Yucatán, Mexico.

Development of a controlled-distance electrochemistry arrangement to be used in power plant environments

International Nuclear Information System (INIS)

Bojinov, M.; Laitinen, T.; Moilanen, P.; Maekelae, K.; Maekelae, M.; Saario, T.; Sirkiae, P.

2000-07-01

This publication presents the state-of-the-art of the controlled-distance electrochemistry (CDE) arrangement developed at VTT. Due to the possibility to control accurately the distance between two electrodes, the CDE arrangement makes possible electrochemical measurements in poorly-conductive media such as simulated coolants of light water reactor systems. This experimental arrangement has now been developed into a versatile electrochemical tool, which can be used for thin-layer electrochemistry (TLEC), wall-jet ring-disc and contact electric impedance (CEI) as well as contact electric resistance (CER) measurements. This report comprises results from the years 1997-1999 and summarises the different possible TLEC configurations and electrode locations as well as the development of a bellows-driven CDE system. (orig.)

Haiti; Request for Extension of the Arrangement Under the Poverty Reduction and Growth Facility: Staff Report

OpenAIRE

International Monetary Fund

2011-01-01

According to the fifth review of the Poverty Reduction and Growth Facility (PRGF) arrangement, the Haitian authorities remain committed to macroeconomic stability under the program. On completion of the fifth review of the PRGF, they requested a new three-year Extended Credit Facility (ECF) arrangement to help sustain economic growth and to preserve macroeconomic stability. The IMF Board approved a three-year arrangement for Haiti under the PRGF. This will help ensure that endorsement of poli...

Dual capacity compressor with reversible motor and controls arrangement therefor

Science.gov (United States)

Sisk, Francis J.

1980-12-02

A hermetic reciprocating compressor such as may be used in heat pump applications is provided for dual capacity operation by providing the crankpin of the crankshaft with an eccentric ring rotatably mounted thereon, and with the end of the connecting rod opposite the piston encompassing the outer circumference of the eccentric ring, with means limiting the rotation of the eccentric ring upon the crankpin between one end point and an opposite angularly displaced end point to provide different values of eccentricity depending upon which end point the eccentric ring is rotated to upon the crankpin, and a reversible motor in the hermetic shell of the compressor for rotating the crankshaft, the motor operating in one direction effecting the angular displacement of the eccentric ring relative to the crankpin to the one end point, and in the opposite direction effecting the angular displacement of the eccentric ring relative to the crankpin to the opposite end point, this arrangement automatically giving different stroke lengths depending upon the direction of motor rotation. The mechanical structure of the arrangement may take various forms including at least one in which any impact of reversal is reduced by utilizing lubricant passages and chambers at the interface area of the crankpin and eccentric ring to provide a dashpot effect. In the main intended application of the arrangement according to the invention, that is, in a refrigerating or air conditioning system, it is desirable to insure a delay during reversal of the direction of compressor operation. A control arrangement is provided in which the control system controls the direction of motor operation in accordance with temperature conditions, the system including control means for effecting operation in a low capacity direction or alternatively in a high capacity direction in response to one set, and another set, respectively, of temperature conditions and with timer means delaying a restart of the compressor

Norrie disease and MAO genes: nearest neighbors.

Science.gov (United States)

Chen, Z Y; Denney, R M; Breakefield, X O

1995-01-01

The Norrie disease and MAO genes are tandemly arranged in the p11.4-p11.3 region of the human X chromosome in the order tel-MAOA-MAOB-NDP-cent. This relationship is conserved in the mouse in the order tel-MAOB-MAOA-NDP-cent. The MAO genes appear to have arisen by tandem duplication of an ancestral MAO gene, but their positional relationship to NDP appears to be random. Distinctive X-linked syndromes have been described for mutations in the MAOA and NDP genes, and in addition, individuals have been identified with contiguous gene syndromes due to chromosomal deletions which encompass two or three of these genes. Loss of function of the NDP gene causes a syndrome of congenital blindness and progressive hearing loss, sometimes accompanied by signs of CNS dysfunction, including variable mental retardation and psychiatric symptoms. Other mutations in the NDP gene have been found to underlie another X-linked eye disease, exudative vitreo-retinopathy. An MAOA deficiency state has been described in one family to date, with features of altered amine and amine metabolite levels, low normal intelligence, apparent difficulty in impulse control and cardiovascular difficulty in affected males. A contiguous gene syndrome in which all three genes are lacking, as well as other as yet unidentified flanking genes, results in severe mental retardation, small stature, seizures and congenital blindness, as well as altered amine and amine metabolites. Issues that remain to be resolved are the function of the NDP gene product, the frequency and phenotype of the MAOA deficiency state, and the possible occurrence and phenotype of an MAOB deficiency state.

Parallel arrangements of positive feedback loops limit cell-to-cell variability in differentiation.

Science.gov (United States)

Dey, Anupam; Barik, Debashis

2017-01-01

Cellular differentiations are often regulated by bistable switches resulting from specific arrangements of multiple positive feedback loops (PFL) fused to one another. Although bistability generates digital responses at the cellular level, stochasticity in chemical reactions causes population heterogeneity in terms of its differentiated states. We hypothesized that the specific arrangements of PFLs may have evolved to minimize the cellular heterogeneity in differentiation. In order to test this we investigated variability in cellular differentiation controlled either by parallel or serial arrangements of multiple PFLs having similar average properties under extrinsic and intrinsic noises. We find that motifs with PFLs fused in parallel to one another around a central regulator are less susceptible to noise as compared to the motifs with PFLs arranged serially. Our calculations suggest that the increased resistance to noise in parallel motifs originate from the less sensitivity of bifurcation points to the extrinsic noise. Whereas estimation of mean residence times indicate that stable branches of bifurcations are robust to intrinsic noise in parallel motifs as compared to serial motifs. Model conclusions are consistent both in AND- and OR-gate input signal configurations and also with two different modeling strategies. Our investigations provide some insight into recent findings that differentiation of preadipocyte to mature adipocyte is controlled by network of parallel PFLs.

Physical vapor deposited films of a perylene derivative: supramolecular arrangement and thermal stability

Energy Technology Data Exchange (ETDEWEB)

Fernandes, Jose Diego; Alessio, Priscila; Silva, Matheus Rodrigues Medeiros; Aroca, Ricardo Flavio; Souza, Agda Eunice de; Constantino, Carlos Jose Leopoldo, E-mail: case@fct.unesp.br [Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Presidente Prudente, SP (Brazil). Dept. de Fisica

2017-07-15

The analysis of supramolecular arrangement is essential to understand the role of this key factor on the optical and electrical properties of organic thin films. In this work, thin solid films of bis(phenethylimido) perylene (PhPTCD) fabricated using physical vapor deposition (PVD) technique (thermal evaporation), deposited simultaneously onto different substrates (Ag mirror, Ge, and quartz plates) contingent on the characterization technique. The main objective is to study the PhPTCD supramolecular arrangement and the thermal stability of this arrangement in PVD films. The ultraviolet-visible absorption reveals a controlled growth of the PVD films, and the micro-Raman scattering data show that the PhPTCD molecule is not thermally degraded in the conditions of these experiments. The microscopy also shows a homogeneous morphological surface of the PVD film at macro and micro scales, with molecular aggregates at nanoscale. Besides, the PVD film roughness does not follow substrate roughness. The X-ray diffraction indicates a crystalline structure for PhPTCD powder and an amorphous form for PhPTCD PVD film. The infrared absorption spectroscopy points to a preferential flat-on organization of the molecules in the PVD films. In addition, the annealing process (200 deg C for 20 minutes) does not affect the supramolecular arrangement of the PhPTCD PVD films. (author)

Performance comparisons of dish type solar concentrator with mirror arrangements and receiver shapes

Energy Technology Data Exchange (ETDEWEB)

Seo, Joo Hyun; Kim, Yong; Ma, Dae Sung; Seo, Tae Beom [Graduate School, Dept. of Mechanical Engineering, Inha Univ., Inchon (Korea, Republic of); Kang, Yong Heack [Korea Inst. of Energy Research, Daejeon (Korea, Republic of)

2008-07-01

The performance comparisons of dish type solar concentrators are numerically investigated. The dish type solar concentrator considered in this paper consists of a receiver and multi-faceted mirrors. In order to investigate the performance comparisons of dish type solar concentrators, six different mirror arrangements and four different receivers are considered. A parabolic-shaped perfect mirror of which diameter is 1.40 m is considered as the reference for the mirror arrangements. The other mirror arrangements consist of twelve identical parabolic-shaped mirror facets of which diameter are 0.405 m. Their total collecting areas, which are 1.545 m{sup 2}, are the same. Four different solar receiver shapes are a conical, a dome, a cylindrical, and a unicorn type. In order to investigate the thermal performance of the dish type solar concentrator, the radiative heat loss in the receiver should be calculated. For calculation, the net radiation method and the Monte-Carlo method are used. Also, because the thermal performance of the dish type solar concentrator can vary as the receiver surface temperature, the various surface temperatures are considered. Based on the calculation, the unicorn type has the best performance in receiver shapes and the STAR has the best performance in mirror arrangements except the perfect mirror. (orig.)

Physical vapor deposited films of a perylene derivative: supramolecular arrangement and thermal stability

International Nuclear Information System (INIS)

Fernandes, Jose Diego; Alessio, Priscila; Silva, Matheus Rodrigues Medeiros; Aroca, Ricardo Flavio; Souza, Agda Eunice de; Constantino, Carlos Jose Leopoldo

2017-01-01

The analysis of supramolecular arrangement is essential to understand the role of this key factor on the optical and electrical properties of organic thin films. In this work, thin solid films of bis(phenethylimido) perylene (PhPTCD) fabricated using physical vapor deposition (PVD) technique (thermal evaporation), deposited simultaneously onto different substrates (Ag mirror, Ge, and quartz plates) contingent on the characterization technique. The main objective is to study the PhPTCD supramolecular arrangement and the thermal stability of this arrangement in PVD films. The ultraviolet-visible absorption reveals a controlled growth of the PVD films, and the micro-Raman scattering data show that the PhPTCD molecule is not thermally degraded in the conditions of these experiments. The microscopy also shows a homogeneous morphological surface of the PVD film at macro and micro scales, with molecular aggregates at nanoscale. Besides, the PVD film roughness does not follow substrate roughness. The X-ray diffraction indicates a crystalline structure for PhPTCD powder and an amorphous form for PhPTCD PVD film. The infrared absorption spectroscopy points to a preferential flat-on organization of the molecules in the PVD films. In addition, the annealing process (200 deg C for 20 minutes) does not affect the supramolecular arrangement of the PhPTCD PVD films. (author)

Establishing neural crest identity: a gene regulatory recipe

Science.gov (United States)

Simões-Costa, Marcos; Bronner, Marianne E.

2015-01-01

The neural crest is a stem/progenitor cell population that contributes to a wide variety of derivatives, including sensory and autonomic ganglia, cartilage and bone of the face and pigment cells of the skin. Unique to vertebrate embryos, it has served as an excellent model system for the study of cell behavior and identity owing to its multipotency, motility and ability to form a broad array of cell types. Neural crest development is thought to be controlled by a suite of transcriptional and epigenetic inputs arranged hierarchically in a gene regulatory network. Here, we examine neural crest development from a gene regulatory perspective and discuss how the underlying genetic circuitry results in the features that define this unique cell population. PMID:25564621

National arrangements for radiotherapy; Mesures nationales pour la radiotherapie. Travail collectif des missions

Energy Technology Data Exchange (ETDEWEB)

NONE

2007-07-01

After a presentation of several letters exchanged between the French health ministry and public agencies in charge of public health or nuclear safety after a radiotherapy accident in Epinal, this report comments the evolution of needs in cancerology care and the place given to radiotherapy. It outlines the technological and organisational evolution of radiotherapy and presents the distribution of radiotherapy equipment, of radio-therapists and other radiotherapy professionals in France. Within the context of radiotherapy accidents which occurred in 2007, it presents the regulatory arrangements which aimed at improving the safety, short term and middle term arrangements which are needed to support and structure radiotherapy practice quality. It stresses the fact that the system will deeply evolve by implementing a radiotherapy vigilance arrangement and a permanent follow-on and adaptation plan based on surveys and the creation of a national committee.

Experimental arrangement to measure dispersion in optical fiber devices

International Nuclear Information System (INIS)

Armas Rivera, Ivan; Beltran Perez, Georgina; Castillo Mixcoatl, Juan; Munoz Aguirre, Severino; Zaca Moran, Placido

2011-01-01

Dispersion is a quite important parameter in systems based on optical fiber, especially in pulsed emission lasers, where the temporal width is affected by such parameter. Therefore, it is necessary to consider the dispersion provoked by each component in the cavity. There are various experimental interferometric arrangements to evaluate this parameter. Generally, these systems modify the wavelength to obtain information about the n(λ) dependency, which is contained in the interferogram phase. However, this makes the system quite slow and it requires tunable and narrow bandwidth laser sources. In the present work, results obtained from an arrangement based on Mach-Zehnder interferometer where one of the arms is the optical fiber under study, while the reference one is air, are presented. In order to determine the n(λ) dependency, a wide spectrum light source was used in the wavelength range of interest. The phase information was evaluated from the interferometric signal measured by an optical spectrum analyzer.

Experimental arrangement to measure dispersion in optical fiber devices

Energy Technology Data Exchange (ETDEWEB)

Armas Rivera, Ivan [Benemerita Universidad Autonoma de Puebla, Facultad de Ciencias de la Electronica (Mexico); Beltran Perez, Georgina; Castillo Mixcoatl, Juan; Munoz Aguirre, Severino [Benemerita Universidad Autonoma de Puebla, Facultad de Ciencias Fisico Matematicas (Mexico); Zaca Moran, Placido, E-mail: ivan_rr1@hotmail.com [Benemerita Universidad Autonoma de Puebla, Fisicoquimica de Materiales ICUAP (Mexico)

2011-01-01

Dispersion is a quite important parameter in systems based on optical fiber, especially in pulsed emission lasers, where the temporal width is affected by such parameter. Therefore, it is necessary to consider the dispersion provoked by each component in the cavity. There are various experimental interferometric arrangements to evaluate this parameter. Generally, these systems modify the wavelength to obtain information about the n({lambda}) dependency, which is contained in the interferogram phase. However, this makes the system quite slow and it requires tunable and narrow bandwidth laser sources. In the present work, results obtained from an arrangement based on Mach-Zehnder interferometer where one of the arms is the optical fiber under study, while the reference one is air, are presented. In order to determine the n({lambda}) dependency, a wide spectrum light source was used in the wavelength range of interest. The phase information was evaluated from the interferometric signal measured by an optical spectrum analyzer.

Vortex structure behind highly heated two cylinders in parallel arrangements

International Nuclear Information System (INIS)

Kurita, Eiichirou; Yahagi, Yuji

2008-01-01

Vortex structures behind twin, highly heated cylinders in parallel arrangements have been investigated experimentally. The experiments were conducted under the following conditions: cylinder diameter, D=4 mm; mean flow velocity, U ∞ =1.0 m/s; Reynolds number, Re=250; cylinder clearance, S/D=0.5 - 1.4; and cylinder heat flux, q=0 - 72.6 kW/m 2 . For S/D > 1.2, the Karman vortex street is formed alternately behind each cylinder divided on the slit flow. The slit flow velocity increases with a decrease in S/D and decreases with increasing heat flux. For S/D 2 ). As a result, the increased local kinematic viscosity and S/D play a key role for the vortex structure and formation behind arrangements of two parallel cylinders. (author)

Livestock farmer perceptions of successful collaborative arrangements for manure exchange

DEFF Research Database (Denmark)

Asai, Masayasu; Langer, Vibeke; Frederiksen, Pia

2014-01-01

to underground water, self-governing manure exchanges have been widely organised among farms in local communities. This allows large livestock farms to achieve the required balance between manure production and the agricultural production area although the importer rarely pays the full nutrient value...... for the manure received. Despite the potential for improved efficiency of manure use, few studies have examined livestock farmers’ perceptions of coordinated arrangements with recipient farms and factors in successful arrangements. A total of 644 manure exporters were asked about factors they consider important...... in identifying and selecting a new partner for manure export, including factors regarding the potential partner and the function of the partnership. They evaluated a total of 18 statements relating to possible perceptions. The results revealed that exporters appreciated especially four qualities: (1) timely...

Effect of Soybean Population and Spatial Arrangement on Nutrient ...

African Journals Online (AJOL)

A field study was conducted in 2007 and 2008 cropping seasons at the research farm of the National Root Crops Research Institute, Umudike, Abia State, to determine the effect of soybean population and spatial arrangement on the productivity of ginger/soybean intercrop in South Eastern Nigeria. Treatments comprised ...

Method and arrangement of distillation of shales

Energy Technology Data Exchange (ETDEWEB)

Bergh, S V

1920-03-29

A method is given of distilling shale and other bituminous materials utilizing the heat from the combustion of the residue, possibly with additional heat from other fuels. It is characterized by the shale, which is arranged in layers, being first submitted to a process of distillation utilizing the heat mentioned, and at the same time recovering the products of distillation, and second the shale being burned without disturbing the layers to any appreciable extent. The patent has 16 more claims.

El Salvador; Request for a Stand-By Arrangement and Cancellation of Current Arrangement: Staff Report; Press Release on the Executive Board Discussion; and Statement by the Executive Director for El Salvador

OpenAIRE

International Monetary Fund

2010-01-01

This paper discusses El Salvador’s Request for a Stand-By Arrangement and cancellation of the current arrangement. The program seeks to preserve financial stability, safeguard the economic recovery, and strengthen the medium-term fiscal position. Fiscal policy will aim at offsetting the impact of the adverse external environment on domestic activity and the most vulnerable while ensuring debt sustainability over the medium term. IMF financial support would have a catalytic role for official c...

Arrangement to reduce the failure frequency of heat condensate pipes

International Nuclear Information System (INIS)

Liskow, E.; Apelt, W.; Krause, W.; Meisel, L.

1988-01-01

The arrangement of throttling devices in heat condensate pipes of NPP with WWER-440 type reactors aims at reducing their failure frequency, ensuring an energetically favourable operation, and enhancing the availability and safety of NPP units

Current status and trends in performance-based risk-sharing arrangements between healthcare payers and medical product manufacturers.

Science.gov (United States)

Carlson, Josh J; Gries, Katharine S; Yeung, Kai; Sullivan, Sean D; Garrison, Louis P

2014-06-01

Our objective was to identify and characterize publicly available cases and related trends for performance-based risk-sharing arrangements (PBRSAs). We performed a review of PBRSAs over the past 20 years (1993-2013) using available databases and reports from colleagues and healthcare experts. These were categorized according to a previously published taxonomy of scheme types and assessed in terms of the underlying product and market attributes for each scheme. Macro-level trends were identified related to the timing of scheme adoption, countries involved, types of arrangements, and product and market factors. Our search yielded 148 arrangements. From this set, 65 arrangements included a coverage with an evidence development component, 20 included a conditional treatment continuation component, 54 included a performance-linked reimbursement component, and 42 included a financial utilization component. Each type of scheme addresses fundamental uncertainties that exist when products enter the market. The pace of adoption appears to be slowing, but new countries continue to implement PBRSAs. Over this 20-year period, there has been a consistent movement toward arrangements that minimize administrative burden. In conclusion, the pace of PBRSA adoption appears to be slowing but still has traction in many health systems. These remain a viable coverage and reimbursement mechanism for a wide range of medical products. The long-term viability and growth of these arrangements will rest in the ability of the parties to develop mutually beneficial arrangements that entail minimal administrative burden in their development and implementation.

International arrangements against nuclear terrorism

International Nuclear Information System (INIS)

Bunn, G.

1987-01-01

International efforts to show the spread of nuclear weapons have created an international norm of nonproliferation, backed by a variety of enforcement mechanisms. Together they are often referred to as the nonproliferation regime. This regime is reviewed, starting with the 1963 Limited Test Ban Treaty. The centerpiece of the regime, the Non-Proliferation Treaty (NPT), signed in 1968, now has 135 parties, including most of the advanced industrial nuclear countries. Results of the 1985 NPT Review Conference are briefly discussed; the 86 NPT parties that attended reaffirmed the treaty's value, pledged continued support for the IAEA safeguards system, and called upon nonsigners to renounce nuclear weapons and accept IAEA safeguards. A section is devoted to the physical protection of nuclear materials, facilities, and weapons. Finally, recommendations are presented to improve international arrangements against nuclear terrorists

High mass isotope separation arrangement

International Nuclear Information System (INIS)

Eerkens, J.W.

1976-01-01

An isotope separation arrangement for separating a preselected isotope from a mixture of chemically-identical but isotopically-different molecules by either photon-induced pure revibrational or vibronic selective excitation of the molecules containing the atoms of the isotope to be separated from a lower to a higher energy state, and a chemical reaction of the higher energy state molecules with a chemically-reactive agent to form a chemical compound containing primarily the atoms of the isotope to be separated in a physicochemical state different from the physicochemical state of the mixture of chemically-identical but isotopically-different molecules. The chemical compound containing the atoms of the isotope to be separated may be subsequently processed to obtain the isotope. The laser configuration used to generate the photon beam is fully described

A preliminary assessment of the market coupling arrangement on the Kontek cable

International Nuclear Information System (INIS)

Kristiansen, Tarjei

2007-01-01

This paper presents a preliminary assessment of the market coupling arrangement on the Kontek (KT) cable between East Denmark and Germany and an assessment of the original auction mechanism. KT, the new spot price area, was introduced in Germany on October 5, 2005 to facilitate a market coupling arrangement on the KT cable between East Denmark and Germany. We would expect the KT price to correlate more with the European Energy Exchange (EEX) price because arbitrage normally levelizes the price. However, spot prices in late 2005 were both high and volatile because congestion management practices in Sweden transferred internal bottlenecks to the cable between Sweden and East Denmark. Since spot prices were equal in East Denmark and the KT area for a substantial time, it implies that some hours had no congestion on the KT cable. Market players valued the previous monthly auctions for transmission capacity more than the daily auctions. Compared to the daily auctions, market players received smaller payoffs on average for the market coupling arrangement, and the smallest payoffs for the monthly auctions

The complete mitochondrial genomes of three parasitic nematodes of birds: a unique gene order and insights into nematode phylogeny

Science.gov (United States)

2013-01-01

Background Analyses of mitochondrial (mt) genome sequences in recent years challenge the current working hypothesis of Nematoda phylogeny proposed from morphology, ecology and nuclear small subunit rRNA gene sequences, and raise the need to sequence additional mt genomes for a broad range of nematode lineages. Results We sequenced the complete mt genomes of three Ascaridia species (family Ascaridiidae) that infest chickens, pigeons and parrots, respectively. These three Ascaridia species have an identical arrangement of mt genes to each other but differ substantially from other nematodes. Phylogenetic analyses of the mt genome sequences of the Ascaridia species, together with 62 other nematode species, support the monophylies of seven high-level taxa of the phylum Nematoda: 1) the subclass Dorylaimia; 2) the orders Rhabditida, Trichinellida and Mermithida; 3) the suborder Rhabditina; and 4) the infraorders Spiruromorpha and Oxyuridomorpha. Analyses of mt genome sequences, however, reject the monophylies of the suborders Spirurina and Tylenchina, and the infraorders Rhabditomorpha, Panagrolaimomorpha and Tylenchomorpha. Monophyly of the infraorder Ascaridomorpha varies depending on the methods of phylogenetic analysis. The Ascaridomorpha was more closely related to the infraorders Rhabditomorpha and Diplogasteromorpha (suborder Rhabditina) than they were to the other two infraorders of the Spirurina: Oxyuridorpha and Spiruromorpha. The closer relationship among Ascaridomorpha, Rhabditomorpha and Diplogasteromorpha was also supported by a shared common pattern of mitochondrial gene arrangement. Conclusions Analyses of mitochondrial genome sequences and gene arrangement has provided novel insights into the phylogenetic relationships among several major lineages of nematodes. Many lineages of nematodes, however, are underrepresented or not represented in these analyses. Expanding taxon sampling is necessary for future phylogenetic studies of nematodes with mt genome

Productivity Commission Submission to the Review of Pricing Arrangements in Residential Aged Care

OpenAIRE

Productivity Commission

2003-01-01

The Commission’s submission to the Review of Pricing Arrangements for Residential Aged Care draws on earlier work, including its inquiry into Nursing Home Subsidies and a major conference on Policy Implications of the Ageing of Australia’s Population. The submission provides an assessment of the current funding and service delivery arrangements for aged care services; an analysis of the implications of ageing, trends in disability rates and other key influences on the future demand for and co...

Flexible working arrangements in healthcare: a comparison between managers of shift workers and 9-to-5 employees.

Science.gov (United States)

Mercer, Danielle; Russell, Elizabeth; Arnold, Kara A

2014-01-01

This study examined healthcare managers' perceptions of flexible working arrangements and implementation barriers. Work-life conflict can lead to negative health implications, but flexible working arrangements can help manage this conflict. Little research has examined its implementation in 24/7/365 healthcare organizations or within groups of employees working 9 AM to 5 PM (9-5) versus shift-work hours. Questionnaires regarding perceptions to, benefits of, and barriers against flexible working arrangements were administered to managers of 9-5 workers and shift workers in an Atlantic Canadian healthcare organization. Few differences in perceptions and benefits of flexible working arrangements were found between management groups. However, results indicate that the interaction with patients and/or the immediacy of tasks being performed are barriers for shift-work managers. The nature of healthcare presents barriers for managers implementing flexible working arrangements, which differ only based on whether the job is physical (shift work) versus desk related (9-5 work).

Feeding methods, sleep arrangement, and infant sleep patterns: a Chinese population-based study.

Science.gov (United States)

Huang, Xiao-Na; Wang, Hui-Shan; Chang, Jen-Jen; Wang, Lin-Hong; Liu, Xi-Cheng; Jiang, Jing-Xiong; An, Lin

2016-02-01

Findings from prior research into the effect of feeding methods on infant sleep are inconsistent. The objectives of this study were to examine infants' sleep patterns by feeding methods and sleep arrangement from birth to eight months old. This longitudinal cohort study enrolled 524 pregnant women at 34-41 weeks of gestation and their infants after delivery in 2006 and followed up until eight months postpartum. The study subjects were recruited from nine women and children hospitals in nine cities in China (Beijing, Chongqing, Wuhan, Changsha, Nanning, Xiamen, Xi'an, Jinan, and Hailin). Participating infants were followed up weekly during the first month and monthly from the second to the eighth month after birth. Twenty-four hour sleep diaries recording infants' sleeping and feeding methods were administered based on caregiver's self-report. Multivariable mixed growth curve models were fitted to estimate the effects of feeding methods and sleep arrangement on infants' sleep patterns over time, controlling for maternal and paternal age, maternal and paternal education level, household income, supplementation of complementary food, and infant birth weight and length. Exclusively formula fed infants had the greatest sleep percentage/24 h, followed by exclusively breast milk fed infants and partially breast milk fed infants (Psleep percentage and night waking frequency between exclusively formula and exclusively breast milk fed infants weakened over time as infants developed. In addition, compared to infants with bed-sharing sleep arrangement, those with room sharing sleep arrangement had greater daytime and 24-hour infant sleep percentage, whereas those with sleeping alone sleep arrangement had greater nighttime sleep percentage. Our data based on caregiver's self-report suggested that partial breastfeeding and bed-sharing may be associated with less sleep in infants. Health care professionals need to work with parents of newborns to develop coping strategies that

Identifying the genes of unconventional high temperature superconductors.

Science.gov (United States)

Hu, Jiangping

We elucidate a recently emergent framework in unifying the two families of high temperature (high [Formula: see text]) superconductors, cuprates and iron-based superconductors. The unification suggests that the latter is simply the counterpart of the former to realize robust extended s-wave pairing symmetries in a square lattice. The unification identifies that the key ingredients (gene) of high [Formula: see text] superconductors is a quasi two dimensional electronic environment in which the d -orbitals of cations that participate in strong in-plane couplings to the p -orbitals of anions are isolated near Fermi energy. With this gene, the superexchange magnetic interactions mediated by anions could maximize their contributions to superconductivity. Creating the gene requires special arrangements between local electronic structures and crystal lattice structures. The speciality explains why high [Formula: see text] superconductors are so rare. An explicit prediction is made to realize high [Formula: see text] superconductivity in Co/Ni-based materials with a quasi two dimensional hexagonal lattice structure formed by trigonal bipyramidal complexes.

The number of pickers and stock-keeping unit arrangement on a uni-directional picking line

Directory of Open Access Journals (Sweden)

Hagspihl, Robert

2014-10-01

Full Text Available The order picking process is often the single largest expense in a distribution centre (DC. The DC considered in this paper uses a picking line configuration to perform order picking. The number of pickers in a picking line, and the initial arrangement of stock-keeping units (SKUs, are two important factors that affect the total completion time of the picking lines. In this paper, the picking line configuration is simulated with an agent-based approach to describe the behaviour of an individual picker. The simulation is then used to analyse the effect of the number of pickers and the SKU arrangement. Verification and validation of this model shows that the model represents the real-world picking line to a satisfactory degree. Marginal analysis (MA was chosen to determine a ‘good’ number of pickers by means of the simulation model. A look-up table is presented to provide decision support for the choice of a ‘good’ number of pickers to improve completion times of the picking line, for the properties of a specific picking line. The initial SKU arrangement on a picking line is shown to be a factor that can affect the level of picker congestion and the total completion time. The greedy ranking and partitioning (GRP and organ pipe arrangement (OPA techniques from the literature, as well as the historical SKU arrangements used by the retailer under consideration, were compared with the proposed classroom discipline heuristic (CDH for SKU arrangement. It was found that the CDH provides an more even spread of SKUs that are picked most frequently, thus decreasing congestion and total completion time.

Birth and death of gene overlaps in vertebrates

Directory of Open Access Journals (Sweden)

Makałowska Izabela

2007-10-01

Full Text Available Abstract Background Between five and fourteen per cent of genes in the vertebrate genomes do overlap sharing some intronic and/or exonic sequence. It was observed that majority of these overlaps are not conserved among vertebrate lineages. Although several mechanisms have been proposed to explain gene overlap origination the evolutionary basis of these phenomenon are still not well understood. Here, we present results of the comparative analysis of several vertebrate genomes. The purpose of this study was to examine overlapping genes in the context of their evolution and mechanisms leading to their origin. Results Based on the presence and arrangement of human overlapping genes orthologs in rodent and fish genomes we developed 15 theoretical scenarios of overlapping genes evolution. Analysis of these theoretical scenarios and close examination of genomic sequences revealed new mechanisms leading to the overlaps evolution and confirmed that many of the vertebrate gene overlaps are not conserved. This study also demonstrates that repetitive elements contribute to the overlapping genes origination and, for the first time, that evolutionary events could lead to the loss of an ancient overlap. Conclusion Birth as well as most probably death of gene overlaps occurred over the entire time of vertebrate evolution and there wasn't any rapid origin or 'big bang' in the course of overlapping genes evolution. The major forces in the gene overlaps origination are transposition and exaptation. Our results also imply that origin of overlapping genes is not an issue of saving space and contracting genomes size.

Linking better shiftwork arrangements with safety and health management systems.

Science.gov (United States)

Kogi, Kazutaka

2004-12-01

Various support measures useful for promoting joint change approaches to the improvement of both shiftworking arrangements and safety and health management systems were reviewed. A particular focus was placed on enterprise-level risk reduction measures linking working hours and management systems. Voluntary industry-based guidelines on night and shift work for department stores and the chemical, automobile and electrical equipment industries were examined. Survey results that had led to the compilation of practicable measures to be included in these guidelines were also examined. The common support measures were then compared with ergonomic checkpoints for plant maintenance work involving irregular nightshifts. On the basis of this analysis, a new night and shift work checklist was designed. Both the guidelines and the plant maintenance work checkpoints were found to commonly cover multiple issues including work schedules and various job-related risks. This close link between shiftwork arrangements and risk management was important as shiftworkers in these industries considered teamwork and welfare services to be essential for managing risks associated with night and shift work. Four areas found suitable for participatory improvement by managers and workers were work schedules, ergonomic work tasks, work environment and training. The checklist designed to facilitate participatory change processes covered all these areas. The checklist developed to describe feasible workplace actions was suitable for integration with comprehensive safety and health management systems and offered valuable opportunities for improving working time arrangements and job content together.

Method of operating an electromagnet arrangement

International Nuclear Information System (INIS)

Goldie, F.T.D.

1988-01-01

A method is described for operating an electromagnet arrangement comprising a main electromagnet and a number of correction coils for applying correction fields to the field produced by the main electromagnet to produce a resultant desired homogeneous magnetic field in a given volume. The method comprises obtaining the least squares fit values for the correction coil currents. If the required current in any coil lies outside a range of permissible values for that coil current a special procedure is described to find the selection of coil currents providing the lowest squared deviation between the desired and actual fields consistent with the permissible currents in the coils. (author)

The effect of mixing-vane arrangements in a subchannel turbulent flow

International Nuclear Information System (INIS)

Ikeno, Tsutomu; Murata, Tamotsu; Kajishima, Takeo

2006-01-01

Large eddy simulation (LES) of developed turbulent flows in a rod bundle was carried out for four spacer designs. The mixing-vanes attached at the spacer were inclined at 30degC or 20deg; they were arranged to promote the swirling or convective flow. These arrangements are possible elements to compose an actual rod bundle. Our LES technique with a consistent higher-order immersed boundary method and a one-equation dynamic sub-grid scale model contributed to an efficient treatment of the complex wall configurations of rods and spacers. The computational results reasonably reproduced experimental results for the drag coefficient and the decay rate of swirling flow. The profiles of the axial velocities and the turbulence intensities indicated reasonable trend for the turbulent flow in the rod bundle. The effect of mixing-vane arrangement on the lateral flows was successfully clarified: the cross flow took the longer way on the rod surface than the swirling flow and then was more significantly influenced by momentum diffusion at the no-slip wall. Therefore, the largely inclined mixing-vanes promoted the cross flow only in the neighborhood of the spacer, the swirling flow inside a subchannel could reach farther downstream than the cross flow. (author)

Implementation of an Arranged Preventive Consultation in Danish General Practice

DEFF Research Database (Denmark)

Junge, Anne Gram; Kirkegaard, Pia; Thomsen, Janus Laust

Background: In 2006 an arranged preventive consultation (0106-service) was implemented in Danish general practice. The purpose of the consultation is an attempt to improve the systematic prevention of the main chronic lifestyle diseases. Aim: This study examines the GP's experiences...... with the arranged preventive consultation with focus on facilitators and barriers in the implementation of the consultation. Material & Method: Semi-structured interviews with 10 GPs and nurses in general practice. Results & Conclusions: Economically lucrative services are not an isolated motivation for the GPs....../nurses, but must be accompanied with a basic belief in the effect of preventive consultations in general practice. The better payment of the 0106-service is used to spend more time per consultation and it makes the GPs/nurses feel rewarded for the preventive work they perform. The consultation frames a social...

Interface stresses in fiber-reinforced materials with regular fiber arrangements

Science.gov (United States)

Mueller, W. H.; Schmauder, S.

The theory of linear elasticity is used here to analyze the stresses inside and at the surface of fiber-reinforced composites. Plane strain, plane stress, and generalized plane strain are analyzed using the shell model and the BHE model and are numerically studied using finite element analysis. Interface stresses are shown to depend weakly on Poisson's ratio. For equal values of the ratio, generalized plane strain and plane strain results are identical. For small volume fractions up to 40 vol pct of fibers, the shell and the BHE models predict the interface stresses very well over a wide range of elastic mismatches and for different fiber arrangements. At higher volume fractions the stresses are influenced by interactions with neighboring fibers. Introducing an external pressure into the shell model allows the prediction of interface stresses in real composite with isolated or regularly arranged fibers.

Parallel arrangements of positive feedback loops limit cell-to-cell variability in differentiation.

Directory of Open Access Journals (Sweden)

Anupam Dey

Full Text Available Cellular differentiations are often regulated by bistable switches resulting from specific arrangements of multiple positive feedback loops (PFL fused to one another. Although bistability generates digital responses at the cellular level, stochasticity in chemical reactions causes population heterogeneity in terms of its differentiated states. We hypothesized that the specific arrangements of PFLs may have evolved to minimize the cellular heterogeneity in differentiation. In order to test this we investigated variability in cellular differentiation controlled either by parallel or serial arrangements of multiple PFLs having similar average properties under extrinsic and intrinsic noises. We find that motifs with PFLs fused in parallel to one another around a central regulator are less susceptible to noise as compared to the motifs with PFLs arranged serially. Our calculations suggest that the increased resistance to noise in parallel motifs originate from the less sensitivity of bifurcation points to the extrinsic noise. Whereas estimation of mean residence times indicate that stable branches of bifurcations are robust to intrinsic noise in parallel motifs as compared to serial motifs. Model conclusions are consistent both in AND- and OR-gate input signal configurations and also with two different modeling strategies. Our investigations provide some insight into recent findings that differentiation of preadipocyte to mature adipocyte is controlled by network of parallel PFLs.

Monitoring arrangement for vented nuclear fuel elements

International Nuclear Information System (INIS)

Campana, R.J.

1981-01-01

In a nuclear fuel reactor core, fuel elements are arranged in a closely packed hexagonal configuration, each fuel element having diametrically opposed vents permitting 180 0 rotation of the fuel elements to counteract bowing. A grid plate engages the fuel elements and forms passages for communicating sets of three, four or six individual vents with respective monitor lines in order to communicate vented radioactive gases from the fuel elements to suitable monitor means in a manner readily permitting detection of leakage in individual fuel elements

Computer-aided beam arrangement based on similar cases in radiation treatment-planning databases for stereotactic lung radiation therapy

International Nuclear Information System (INIS)

Magome, Taiki; Shioyama, Yoshiyuki; Arimura, Hidetaka

2013-01-01

The purpose of this study was to develop a computer-aided method for determination of beam arrangements based on similar cases in a radiotherapy treatment-planning database for stereotactic lung radiation therapy. Similar-case-based beam arrangements were automatically determined based on the following two steps. First, the five most similar cases were searched, based on geometrical features related to the location, size and shape of the planning target volume, lung and spinal cord. Second, five beam arrangements of an objective case were automatically determined by registering five similar cases with the objective case, with respect to lung regions, by means of a linear registration technique. For evaluation of the beam arrangements five treatment plans were manually created by applying the beam arrangements determined in the second step to the objective case. The most usable beam arrangement was selected by sorting the five treatment plans based on eight plan evaluation indices, including the D95, mean lung dose and spinal cord maximum dose. We applied the proposed method to 10 test cases, by using an RTP database of 81 cases with lung cancer, and compared the eight plan evaluation indices between the original treatment plan and the corresponding most usable similar-case-based treatment plan. As a result, the proposed method may provide usable beam arrangements, which have no statistically significant differences from the original beam arrangements (P>0.05) in terms of the eight plan evaluation indices. Therefore, the proposed method could be employed as an educational tool for less experienced treatment planners. (author)

Combining informal care and paid work: The use of work arrangements by working adult-child caregivers in the Netherlands.

Science.gov (United States)

Oldenkamp, Marloes; Bültmann, Ute; Wittek, Rafael P M; Stolk, Ronald P; Hagedoorn, Mariët; Smidt, Nynke

2018-01-01

An increasing number of people combine paid work with the provision of informal care for a loved one. This combination of work and care may cause difficulties, necessitating adaptations at work, i.e. work arrangements. The present study explores what types of work arrangements are used by working caregivers, and which caregiver, care and work characteristics are associated with the use of these work arrangements. Within the Lifelines Informal Care Add-on Study (Lifelines ICAS), data on 965 Dutch informal caregivers in the North of the Netherlands were collected between May 2013 and July 2014 (response rate 48%), and data on 333 working adult-child caregivers (aged 26-68 years, 82% female) were used in this study. A small majority (56%) of the working caregivers used one or more work arrangement(s): taking time off (41%), individual agreements with supervisor (30%), formal care leave arrangement (13%), and reduction in paid work hours (6%). Logistic regression analyses showed that long working hours (OR 1.06, 95% CI 1.01-1.08), and the experience of more health problems (OR 2.54, 95% CI 1.56-4.05) or a disrupted schedule due to caregiving (OR 2.50, 95% CI 1.66-3.78) increased the chance to have used one or more work arrangements. Lower educated working caregivers were less likely to have used a formal care leave arrangement (tertiary vs. primary education OR 2.75, 95% CI 1.13-6.67; tertiary vs. secondary education OR 1.27, 95% CI 1.27-5.09). Policy makers should inform working caregivers about the availability of the different work arrangements, with specific attention for low educated working caregivers. Employers need to consider a more caregiver-friendly policy, as almost half of the working adult-child caregivers did not use any work arrangement. © 2017 John Wiley & Sons Ltd.

Valve arrangement for a nuclear plant residual heat removal system

International Nuclear Information System (INIS)

Fidler, G.L.; Hill, R.A.; Carrera, J.P.

1978-01-01

Disclosed is an improved valve arrangement for a two-train Residual Heat Removal System (RHRS) of a nuclear reactor plant which ensures operational integrity of the system under single failure circumstances including loss of one of two electrical power sources

Parents' experiences of flexible work arrangements in changing European workplaces

NARCIS (Netherlands)

S. Lewis (Suzan); L. den Dulk (Laura)

2009-01-01

textabstractVarious leaves and other forms of flexible working arrangements have been implemented in workplaces to support employees with family commitments. Some are a response to public policy, others developed voluntarily. However, research examining the effectiveness of these policies in a

17 CFR 270.7d-1 - Specification of conditions and arrangements for Canadian management investment companies...

Science.gov (United States)

2010-04-01

... and arrangements for Canadian management investment companies requesting order permitting registration... arrangements for Canadian management investment companies requesting order permitting registration. (a) A management investment company organized under the laws of Canada or any province thereof may obtain an order...

The long-term experiences of surrogates: relationships and contact with surrogacy families in genetic and gestational surrogacy arrangements.

Science.gov (United States)

Imrie, Susan; Jadva, Vasanti

2014-10-01

This study examined the contact arrangements and relationships between surrogates and surrogacy families and whether these outcomes differed according to the type of surrogacy undertaken. Surrogates' motivations for carrying out multiple surrogacy arrangements were also examined, and surrogates' psychological health was assessed. Semi-structured interviews were administered to 34 women who had given birth to a child conceived through surrogacy approximately 7 years prior to interview. Some surrogates had carried out multiple surrogacy arrangements, and data were collected on the frequency, type of contact, and surrogate's feelings about the level of contact in each surrogacy arrangement, the surrogate's relationship with each child and parent, and her experience of, and motivation for, each surrogacy. Questionnaire measures of psychological health were administered. Surrogates had completed a total of 102 surrogacy arrangements and remained in contact with the majority of families, and reported positive relationships in most cases. Surrogates were happy with their level of contact in the majority of arrangements and most were viewed as positive experiences. Few differences were found according to surrogacy type. The primary motivation given for multiple surrogacy arrangements was to help couples have a sibling for an existing child. Most surrogates showed no psychological health problems at the time of data collection. Copyright © 2014 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

High frequency ignition arrangement

Energy Technology Data Exchange (ETDEWEB)

Canup, R E

1977-03-03

The invention concerns an HF ignition arrangement for combustion engines with a transistor oscillator. As this oscillator requires a current of 10A, with peak currents up to about 50A, it is not sensible to take this current through the remote ignition switch for switching it on and off. According to the invention the HF high voltage transformer of the ignition is provided with a control winding, which only requires a few milliamps DC and which can therefore be switched via the ignition switch. If the ignition switch is in the 'running' position, then a premagnetising DC current flows through the control winding, which suppresses the oscillation of the oscillator which has current flowing through it, until this current is interrupted by the interruptor contacts controlled by the combustion engine, so that the oscillations of the oscillator start immediately; the oscillator only continues to oscillate during the period during which the interruptor contacts controlled by the machine are open and interrupt the premagnetisation current. The control winding is short circuited in the 'off' position of the ignition switch.

MUSICAL ARRANGEMENT OF MEDIA ADS

Directory of Open Access Journals (Sweden)

Chernyshov Alexander V.

2015-01-01

Full Text Available The music-compositional principles of commercial and political advertising and also the self-promotion of electronic media (radio, television, Internet are considered in this mediatext: from the elementary beeps, symbolic functions, emblems/logos and musical brands to the sound engineering technology to underscore the product's name and the complex synthesis between music and intra movements and color-light design of frames. Simultaneously examines, how the musical arrangement of ethereal advertising is involved in creation the emotional drama or bravado which reach the level of explicit or associative counterpoint 'music with the advertised object or subject' and which extend to expression of cultural image of all the broadcast channel. The article explores the works of the next genres like infomercial, teleshopping, film-ad, and autonomous commercials that have been produced in European countries or USA.

Contractual arrangements and food quality certifications in the Mexican avocado industry

Directory of Open Access Journals (Sweden)

J. J. Arana-Coronado

2013-03-01

Full Text Available The adoption of private quality certifications in agrifood supply chains often requires specific investments by producers which can be safeguarded by choosing specific contractual arrangements. Based on a survey data from avocado producers in Mexico, this paper aims to analyze the impact of transaction costs and relationship characteristics of the joint choice of contractual arrangements and quality certifications. Using a bivariate probit model, it shows that a producer’s decision to adopt private quality certifications is directly linked to high levels of asset specificity and price. In order to ensure the high level of specificity under the presence of low levels of price uncertainty, producers have relied on relational governance supported by the expectation of continuity in their bilateral relationships with buyers.

Living Arrangement and Life Satisfaction in Older Malaysians: The Mediating Role of Social Support Function

Science.gov (United States)

Kooshiar, Hadi; Yahaya, Nurizan; Hamid, Tengku Aizan; Abu Samah, Asnarulkhadi; Sedaghat Jou, Vajiheh

2012-01-01

Background This cross-sectional and correlational survey examines the association between different types of living arrangements and life satisfaction in older Malaysians, while taking into account the mediating effects of social support function. Methodology and Findings A total of 1880 of older adults were selected by multistage stratified sampling. Life satisfaction and social support were measured with the Philadelphia Geriatric Center Morale Scale and Medical Outcomes Study Social Support Survey. The result shows living with children as the commonest type of living arrangement for older adults in peninsular Malaysia. Compared to living alone, living only with a spouse especially and then co-residency with children were both associated with better life satisfaction (psocial support function (psocial support function enhanced the relation between living arrangements and life satisfaction. Conclusion This study revealed that types of living arrangement directly, and indirectly through social support function, play an important role in predicting life satisfaction for older adults in Malaysia. This study makes remarkable contributions to the Convoy model in older Malaysians. PMID:22912806

Improved microgrid arrangement for integrated imaging polarimeters.

Science.gov (United States)

LeMaster, Daniel A; Hirakawa, Keigo

2014-04-01

For almost 20 years, microgrid polarimetric imaging systems have been built using a 2×2 repeating pattern of polarization analyzers. In this Letter, we show that superior spatial resolution is achieved over this 2×2 case when the analyzers are arranged in a 2×4 repeating pattern. This unconventional result, in which a more distributed sampling pattern results in finer spatial resolution, is also achieved without affecting the conditioning of the polarimetric data-reduction matrix. Proof is provided theoretically and through Stokes image reconstruction of synthesized data.

The Mouse Solitary Odorant Receptor Gene Promoters as Models for the Study of Odorant Receptor Gene Choice.

Directory of Open Access Journals (Sweden)

Andrea Degl'Innocenti

Full Text Available In vertebrates, several anatomical regions located within the nasal cavity mediate olfaction. Among these, the main olfactory epithelium detects most conventional odorants. Olfactory sensory neurons, provided with cilia exposed to the air, detect volatile chemicals via an extremely large family of seven-transmembrane chemoreceptors named odorant receptors. Their genes are expressed in a monogenic and monoallelic fashion: a single allele of a single odorant receptor gene is transcribed in a given mature neuron, through a still uncharacterized molecular mechanism known as odorant receptor gene choice.Odorant receptor genes are typically arranged in genomic clusters, but a few are isolated (we call them solitary from the others within a region broader than 1 Mb upstream and downstream with respect to their transcript's coordinates. The study of clustered genes is problematic, because of redundancy and ambiguities in their regulatory elements: we propose to use the solitary genes as simplified models to understand odorant receptor gene choice.Here we define number and identity of the solitary genes in the mouse genome (C57BL/6J, and assess the conservation of the solitary status in some mammalian orthologs. Furthermore, we locate their putative promoters, predict their homeodomain binding sites (commonly present in the promoters of odorant receptor genes and compare candidate promoter sequences with those of wild-caught mice. We also provide expression data from histological sections.In the mouse genome there are eight intact solitary genes: Olfr19 (M12, Olfr49, Olfr266, Olfr267, Olfr370, Olfr371, Olfr466, Olfr1402; five are conserved as solitary in rat. These genes are all expressed in the main olfactory epithelium of three-day-old mice. The C57BL/6J candidate promoter of Olfr370 has considerably varied compared to its wild-type counterpart. Within the putative promoter for Olfr266 a homeodomain binding site is predicted. As a whole, our findings

The Transport of Radioactive Materials under special arrangement

International Nuclear Information System (INIS)

Biaggio, A.L.; Vietri, J.R.L.

1993-01-01

The Agency's Regulations for the Safe Transport of Radioactive Material rule the international transport of these materials and provide the basis of national and regional regulations. The Regulations establish the technical, operational and administrative requirements which shall be accomplished to carry out the transport of radioactive materials (RAM). They also allow the transport in different conditions of those currently applicable and, in such cases, establish that the transport shall be made under special arrangement. To approve a transport under special arrangement the involved Competent Authority shall be satisfied that the alternative provisions are adequate to ensure that the overall level of safety in transport and in-transit storage is at least equivalent to that which would be provided if all the applicable requirements had been met (para. 2ll of the International Atomic Energy Agency Safety Series No. 6). This paper explains some difficulties the Argentine Competent. Authority has experienced trying by comparing the equivalence between the level of safety resulting from the compliance with current requirements and the overall level of safety which is provided by the application of alternative provisions. As most of the experience gained come from the transport of RAM by road, only this mode of transport is considered. (J.P.N.)

High-Resolution Chromosome Ideogram Representation of Currently Recognized Genes for Autism Spectrum Disorders

Directory of Open Access Journals (Sweden)

Merlin G. Butler

2015-03-01

Full Text Available Recently, autism-related research has focused on the identification of various genes and disturbed pathways causing the genetically heterogeneous group of autism spectrum disorders (ASD. The list of autism-related genes has significantly increased due to better awareness with advances in genetic technology and expanding searchable genomic databases. We compiled a master list of known and clinically relevant autism spectrum disorder genes identified with supporting evidence from peer-reviewed medical literature sources by searching key words related to autism and genetics and from authoritative autism-related public access websites, such as the Simons Foundation Autism Research Institute autism genomic database dedicated to gene discovery and characterization. Our list consists of 792 genes arranged in alphabetical order in tabular form with gene symbols placed on high-resolution human chromosome ideograms, thereby enabling clinical and laboratory geneticists and genetic counsellors to access convenient visual images of the location and distribution of ASD genes. Meaningful correlations of the observed phenotype in patients with suspected/confirmed ASD gene(s at the chromosome region or breakpoint band site can be made to inform diagnosis and gene-based personalized care and provide genetic counselling for families.

Choice of the recording arrangement for bubble chamber holography

International Nuclear Information System (INIS)

Royer, H.

1982-01-01

The main characteristics of the different recording arrangements are compared. The in-line system is the most simple and the cheapest but it does not suit to all types of chambers. The side-band systems yield different sorts of images and require different coherence, stability and energy conditions according to the type of illumination of the bubbles. (orig.)

Effects of Magnetic Particles Entrance Arrangements on Mixing Efficiency of a Magnetic Bead Micromixer

Institute of Scientific and Technical Information of China (English)

Reza Kamali; Seyed Alireza Shekoohi; Alireza Binesh

2014-01-01

In this study, a computer code is developed to numerically investigate a magnetic bead micromixer under different conditions. The micromixer consists of a microchannel and numerous micro magnetic particles which enter the micromixer by fluid flows and are actuated by an alternating magnetic field normal to the main flow. An important feature of micromixer which is not considered before by researchers is the particle entrance arrangement into the micromixer. This parameter could effectively affect the micromixer efficiency. There are two general micro magnetic particle entrance arrangements in magnetic bead micromixers: determined position entrance and random position entrance. In the case of determined position entrances, micro magnetic particles enter the micromixer at specific positions of entrance cross section. However, in a random position entrance,particles enter the microchannel with no order. In this study mixing efficiencies of identical magnetic bead micromixers which only differ in particle entrance arrangement are numerically investigated and compared.The results reported in this paper illustrate that the prepared computer code can be one of the most powerful and beneficial tools for the magnetic bead micromixer performance analysis. In addition, the results show that some features of the magnetic bead micromixer are strongly affected by the entrance arrangement of the particles.

Small-Firm Networks: hybrid arrangement or organizational form?

OpenAIRE

Verschoore, Jorge Renato; Balestrin, Alsones; Perucia, Alexandre

2014-01-01

In the field of organizations, one relevant question is whether or not to consider networks as organizational forms. On the one hand, Williamson (1985) says that networks are hybrid arrangements. On the other, authors like Powell (1990) argue that networks constitute themselves as organizational forms. Given this dilemma, the present article proposes the analysis of organizational characteristics of small-firm networks (SFN). To reach such objective, twelve SFNs in distinct stages of developm...

Systematic analysis of the heat exchanger arrangement problem using multi-objective genetic optimization

International Nuclear Information System (INIS)

Daróczy, László; Janiga, Gábor; Thévenin, Dominique

2014-01-01

A two-dimensional cross-flow tube bank heat exchanger arrangement problem with internal laminar flow is considered in this work. The objective is to optimize the arrangement of tubes and find the most favorable geometries, in order to simultaneously maximize the rate of heat exchange while obtaining a minimum pressure loss. A systematic study was performed involving a large number of simulations. The global optimization method NSGA-II was retained. A fully automatized in-house optimization environment was used to solve the problem, including mesh generation and CFD (computational fluid dynamics) simulations. The optimization was performed in parallel on a Linux cluster with a very good speed-up. The main purpose of this article is to illustrate and analyze a heat exchanger arrangement problem in its most general form and to provide a fundamental understanding of the structure of the Pareto front and optimal geometries. The considered conditions are particularly suited for low-power applications, as found in a growing number of practical systems in an effort toward increasing energy efficiency. For such a detailed analysis with more than 140 000 CFD-based evaluations, a design-of-experiment study involving a response surface would not be sufficient. Instead, all evaluations rely on a direct solution using a CFD solver. - Highlights: • Cross-flow tube bank heat exchanger arrangement problem. • A fully automatized multi-objective optimization based on genetic algorithm. • A systematic study involving a large number of CFD (computational fluid dynamics) simulations

Markov State Models Reveal a Two-Step Mechanism of miRNA Loading into the Human Argonaute Protein: Selective Binding followed by Structural Re-arrangement

KAUST Repository

Jiang, Hanlun

2015-07-16

Argonaute (Ago) proteins and microRNAs (miRNAs) are central components in RNA interference, which is a key cellular mechanism for sequence-specific gene silencing. Despite intensive studies, molecular mechanisms of how Ago recognizes miRNA remain largely elusive. In this study, we propose a two-step mechanism for this molecular recognition: selective binding followed by structural re-arrangement. Our model is based on the results of a combination of Markov State Models (MSMs), large-scale protein-RNA docking, and molecular dynamics (MD) simulations. Using MSMs, we identify an open state of apo human Ago-2 in fast equilibrium with partially open and closed states. Conformations in this open state are distinguished by their largely exposed binding grooves that can geometrically accommodate miRNA as indicated in our protein-RNA docking studies. miRNA may then selectively bind to these open conformations. Upon the initial binding, the complex may perform further structural re-arrangement as shown in our MD simulations and eventually reach the stable binary complex structure. Our results provide novel insights in Ago-miRNA recognition mechanisms and our methodology holds great potential to be widely applied in the studies of other important molecular recognition systems.

Markov State Models Reveal a Two-Step Mechanism of miRNA Loading into the Human Argonaute Protein: Selective Binding followed by Structural Re-arrangement

KAUST Repository

Jiang, Hanlun; Sheong, Fu Kit; Zhu, Lizhe; Gao, Xin; Bernauer, Julie; Huang, Xuhui

2015-01-01

Argonaute (Ago) proteins and microRNAs (miRNAs) are central components in RNA interference, which is a key cellular mechanism for sequence-specific gene silencing. Despite intensive studies, molecular mechanisms of how Ago recognizes miRNA remain largely elusive. In this study, we propose a two-step mechanism for this molecular recognition: selective binding followed by structural re-arrangement. Our model is based on the results of a combination of Markov State Models (MSMs), large-scale protein-RNA docking, and molecular dynamics (MD) simulations. Using MSMs, we identify an open state of apo human Ago-2 in fast equilibrium with partially open and closed states. Conformations in this open state are distinguished by their largely exposed binding grooves that can geometrically accommodate miRNA as indicated in our protein-RNA docking studies. miRNA may then selectively bind to these open conformations. Upon the initial binding, the complex may perform further structural re-arrangement as shown in our MD simulations and eventually reach the stable binary complex structure. Our results provide novel insights in Ago-miRNA recognition mechanisms and our methodology holds great potential to be widely applied in the studies of other important molecular recognition systems.

Individual Differences: Factors Affecting Employee Utilization of Flexible Work Arrangements

Science.gov (United States)

Lambert, Alysa D.; Marler, Janet H.; Gueutal, Hal G.

2008-01-01

This study investigated individual and organizational factors that predict an individual's choice to use flexible work arrangements (FWAs). Survey data was collected from 144 employees in two different organizations. The results revealed several significant predictors of FWAs: tenure, hours worked per week, supervisory responsibilities,…

Radioactive probes for human gene localisation by in situ hybridisation

International Nuclear Information System (INIS)

Fennell, S.J.

1980-07-01

Radioactive probes of high specific activity have been used for human gene localisation on metaphase chromosome preparations. Human 5S ribosomal RNA was used as a model system, as a probe for the localisation of human 5S ribosomal genes. 125 I-labelled mouse 5S ribosomal RNA was used to study the 5S ribosomal gene content and arrangement in families with translocations on the long arm of chromosome 1 close to or containing the 5S ribosomal RNA locus, by in situ hybridisation to human metaphase chromosomes from peripheral blood cultures. This confirmed the chromosomal assignment of 5S ribosomal genes to 1q 42-43. In situ hybridisation probes were also prepared from recombinant plasmids containing Xenopus laevis oocyte 5S or 28S/18S gene sequences to give [ 3 H]-labelled cRNA and [ 3 H]-labelled nick-translated plasmid DNA. Studies on the kinetics of hybridisation of plasmid probes with and without ribosomal gene sequences questioned the role of plasmid DNA for amplification of signal during gene localisation. Gene localisation was obtained with nick-translated plasmid DNA containing the 28S/18S ribosomal DNA insert after short exposure times, but poor results were obtained using a [ 3 H]-labelled cRNA probe transcribed from the plasmid with the 5S gene insert. (author)

Albania; Request for a Three-Year Arrangement Under the Poverty Reduction and Growth Facility

OpenAIRE

International Monetary Fund

2002-01-01

This paper evaluates Albania’s Request for a Three-Year Arrangement Under the Poverty Reduction and Growth Facility (PRGF). Sound financial policies under the previous PRGF-supported program helped stabilize the economy and restore high growth, but poverty remains widespread. The authorities’ medium-term strategy aims to promote inclusive growth, as the country continues to be plagued by poverty. The proposed PRGF arrangement is justified by the authorities’ commendable performance under the ...

A High-gain and Low-scattering Waveguide Slot Antenna of Artificial Magnetic Conductor Octagonal Ring Arrangement

Directory of Open Access Journals (Sweden)

X. Liu

2016-04-01

Full Text Available A novel design of high-gain and low-scattering waveguide slot antenna is proposed in this paper. Firstly the scattering pattern of artificial magnetic conductor (AMC composite surface is estimated by array factor analysis method. The comparison between octagonal ring arrangement and chessboard arrangement proves that the former arrangement has the characteristic of diffuseness-like and expands the bandwidth of radar cross section (RCS reduction. Secondly, the metal surface of waveguide slot antenna (WSA is replaced by the octagonal ring arrangement composite surface (ORACS. The gain is improved because of spurious radiation units which are around the slot. At the same time using the phase cancellation principle, a backscatter null achieves RCS reduction in the vertical direction. Experimental results show that the novel antenna after loading with the ORACS, the gain is improved by 5dB; the bandwidth of RCS reduction (reduction greater than 10dB is 5.24-5.92 GHz.

The work of musicians in Brazil: identity tensions and domestic arrangements

Directory of Open Access Journals (Sweden)

Jordão Horta Nunes

2017-07-01

Full Text Available The musicians’ job market in Brazil is heterogeneous in various senses. It is characterized by informality and job insecurity, in addition to being segmented by gender, both with respect to musical forms and to social relations between the sexes and the construction of correlative social representations. The purpose of this article is to analyze the work of musicians in Brazil, highlighting the recent occupational displacement that affects professional identities and the conciliation practices and domestic arrangements in households where musicians live. The methodology used was a quali-quantitative approach and the triangulation of sources: government databases, and surveys using Internet profiles selected through web scraping and interviews. The exploratory factor analysis based on variables related to domestic work and musical work identified five factors: traditional delegation arrangement, competitive musical work, societal conciliation arrangement, internal conciliation, and community conciliation. Findings showed that traditional delegation in the case of domestic work is not only explained by the relation between reproductive and productive work, with the traditional devaluation or subalternization of the former, but also by a gender construction that ends up assigning women–who are a minority in terms of employment–to teaching activities in the field of higher education and to their placement in stable formations, generally with higher performance and less flexible forms of hiring. Conciliation strategies involving musical work reflect the distinction, in the context of specific cultural and social characteristics, among orienting oneself through the assistance available in the services market, the State, or family arrangements, seen as ideal types, since these practices overlap. However, on the basis of the abovementioned factors, the current outlook reveals an imbalance with respect to the experience and

Mounting arrangement for the drive system of an air-bearing spindle on a machine tool

Science.gov (United States)

Lunsford, J.S.; Crisp, D.W.; Petrowski, P.L.

1987-12-07

The present invention is directed to a mounting arrangement for the drive system of an air-bearing spindle utilized on a machine tool such as a lathe. The mounting arrangement of the present invention comprises a housing which is secured to the casing of the air bearing in such a manner that the housing position can be selectively adjusted to provide alignment of the air-bearing drive shaft supported by the housing and the air-bearing spindle. Once this alignment is achieved the air between spindle and the drive arrangement is maintained in permanent alignment so as to overcome misalignment problems encountered in the operation of the machine tool between the air-bearing spindle and the shaft utilized for driving the air-bearing spindle.

75 FR 34941 - Review of the Commission's Program Access Rules and Examination of Programming Tying Arrangements

Science.gov (United States)

2010-06-21

... Commission's Program Access Rules and Examination of Programming Tying Arrangements AGENCY: Federal... Program Access Rules and Examination of Programming Tying Arrangements, MB Docket No. 07-198, FCC 10-17... information collection is contained in Sections 4(i), 303(r), and 628 of the Communications Act of 1934, as...

Ionization chamber circuit arrangement for counterbalancing long-term aging processes

International Nuclear Information System (INIS)

Fischer, H.; Goeldner, R.; Grosse, H.J.; Reinhardt, K.

1985-01-01

The described circuit arrangement changes the amplification of the output signal during the lifetime of the ionization chamber in such a way that the sensitivity of the detector becomes independent of the decreasing activity of the radiation source. It is suitable for ionization flue gas detectors

Influence of spatial arrangements on performance of a yam-maize ...

African Journals Online (AJOL)

Influence of spatial arrangements on performance of a yam-maize-pepper intercrop. JA Manu-Aduening, K Boa-Amponsem. Abstract. No Abstract. Ghana Journal of Agricultural Science No. 1, 2005: 29-35. Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT.

46 CFR 133.110 - Survival craft muster and embarkation arrangements.

Science.gov (United States)

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Survival craft muster and embarkation arrangements. 133... VESSELS LIFESAVING SYSTEMS Requirements for All OSVs § 133.110 Survival craft muster and embarkation... lighting supplied from the emergency source of electrical power. (e) Each davit-launched survival craft...

Innovative Nuclear Power Plant Building Arrangement in Consideration of Decommissioning

Directory of Open Access Journals (Sweden)

Won-Jun Choi

2017-04-01

Full Text Available A new concept termed the Innovative Nuclear Power Plant Building Arrangement (INBA strategy is a new nuclear power plant building arrangement method which encompasses upfront consideration of more efficient decommissioning. Although existing decommissioning strategies such as immediate dismantling and differed dismantling has the advantage of either early site restoration or radioactive decommissioning waste reduction, the INBA strategy has the advantages of both strategies. In this research paper, the concept and the implementation method of the INBA strategy will be described. Two primary benefits will be further described: (1 early site restoration; and (2 radioactive waste reduction. Several other potential benefits will also be identified. For the estimation of economic benefit, the INBA strategy, with two primary benefits, will be compared with the immediate dismantling strategy. The effect of a short life cycle nuclear power plant in combination with the INBA strategy will be reviewed. Finally, some of the major impediments to the realization of this strategy will be discussed.

Contract Hog Production: A Case Study of Financial Arrangements

OpenAIRE

Ross, Brent; Barry, Peter

2005-01-01

A case study is presented about the financing arrangements, contract terms, and business relationships of a set of contract hog producers whose loans from community banks have been guaranteed by the Illinois Farm Development Authority. The results reflect the maturity and stability of contract hog production, although agribusiness and farmer integrators largely fill different market niches and contract with different types of producers.

Employee satisfaction and use of flexible working arrangements

OpenAIRE

Wheatley, D

2017-01-01

This paper considers the impact of flexible working arrangements (FWAs), using the British Household Panel Survey and Understanding Society, 2001-2010/11. Results of panel logit, ANCOVA and change-score analysis are indicative of positive impacts from use of a number of FWAs, including homeworking having positive effects for men and women on job and leisure satisfaction. However,\\ud findings reveal gaps in availability and use of FWAs, and highlight the gendered nature of flexible employment....

Investigation of airflow effects on the dielectric barrier discharge with single/double discharge channel arrangement

Science.gov (United States)

Fan, Zhihui; Yan, Huijie; Liu, Yidi; Guo, Hongfei; Wang, Yuying; Ren, Chunsheng

2018-05-01

Atmospheric-pressure dielectric barrier discharge (DBD) with airflow participation has been widely used in recent years. In this paper, effects of airflow on DBD characteristics are experimentally investigated by single/double pin-to-plate DBD arrangements with an AC exciting source. The discharge electrical characteristics and the movements of discharge channels in airflow are investigated with a single pin electrode arrangement. The current intensities increase in positive cycles and decrease in negative cycles with the increase in airflow velocity. The transition from a filamentary discharge to a diffuse discharge is observed under certain airflow conditions, and the discharge channels move with the airflow with a movement velocity less than the corresponding airflow velocity. In the cases of double pin electrode arrangements, the repulsion between double pin discharge channels is apparent at a 10 mm distance but is not obvious at a 20 mm distance. When the airflow is introduced into the discharge gap, not as in the case of single pin electrode arrangement, the movements of discharge channels in airflow are affected by adjacent discharge channels. The corresponding reasons are analyzed in the paper.

Direct dimethyl-ether (DME) synthesis by spatial patterned catalyst arrangement. A modeling and simulation study

Energy Technology Data Exchange (ETDEWEB)

McBride, K.; Turek, T.; Guettel, R. [Clausthal Univ. of Technology (Germany). Inst. of Chemical Process Engineering

2011-07-01

The effect of spatially patterned catalyst beds was investigated for direct DME synthesis from synthesis gas as an example. A layered arrangement of methanol synthesis and dehydration catalyst was chosen and studied by numerical simulation under typical operating conditions for single-step DME synthesis. It was revealed that catalyst layers significantly influence the DME productivity. With an increasing number of layers from 2 to 40, an increase in DME productivity was observed approaching the performance of a physical catalyst mixture for an infinite number of layers. The results prove that a physical mixture of methanol synthesis and dehydration catalyst achieves the highest DME productivity under operating conditions chosen in this study. This can be explained by the higher average methanol concentration for the layered catalyst arrangement and thus stronger equilibrium constraints for the methanol synthesis reaction. Essentially, the layered catalyst arrangement is comparable to a cascade model of the two-step process, which is less efficient in terms of DME yield than the single-step process. However, since a significant effect was found, the layered catalyst arrangement could be beneficial for other reaction systems. (orig.)

Inequality of pension arrangements among different segments of the labor force in China.

Science.gov (United States)

Wu, Ling

2013-01-01

Social security for older people in China today has been established institutionally. However, there are substantial problems such as coverage, affordability, fund management, and corruption. This paper aims to provide a general picture of China's social security system for older people and to argue that the inequality of pension arrangements among different segments of the labor force is one of the most conspicuous problems challenging the Chinese government. Four unequal aspects of the pension system concerning the financing resources and pension levels are examined in this paper: (1) unequal institutional arrangements among different sectors, (2) unbalanced governmental expenditure in pension provision, (3) an increasing gap in pension levels between urban and rural areas, and (4) uncovered groups such as the unemployed and self-employed. Historical, economic, and political reasons all contribute to this unequal institution under transition from socialism to a market-oriented economy. At present, it is urgent for the central government to take measures to integrate the various pension arrangements into the unified Old Age Insurance and to reduce the gaps among different regions.

Economic and Nonproliferation Analysis Framework for Assessing Reliable Nuclear Fuel Service Arrangements

International Nuclear Information System (INIS)

Phillips, Jon R.; Kreyling, Sean J.; Short, Steven M.; Weimar, Mark R.

2010-01-01

Nuclear power is now broadly recognized as an essential technology in national strategies to provide energy security while meeting carbon management goals. Yet a long standing conundrum remains: how to enable rapid growth in the global nuclear power infrastructure while controlling the spread of sensitive enrichment and reprocessing technologies that lie at the heart of nuclear fuel supply and nuclear weapons programs. Reducing the latent proliferation risk posed by a broader horizontal spread of enrichment and reprocessing technology has been a primary goal of national nuclear supplier policies since the beginning of the nuclear power age. Attempts to control the spread of sensitive nuclear technology have been the subject of numerous initiatives in the intervening decades sometimes taking the form of calls to develop fuel supply and service assurances to reduce market pull to increase the number of states with fuel cycle capabilities. A clear understanding of what characteristics of specific reliable nuclear fuel service (RNFS) and supply arrangements qualify them as 'attractive offers' is critical to the success of current and future efforts. At a minimum, RNFS arrangements should provide economic value to all participants and help reduce latent proliferation risks posed by the global expansion of nuclear power. In order to inform the technical debate and the development of policy, Pacific Northwest National Laboratory has been developing an analytical framework to evaluate the economics and nonproliferation merits of alternative approaches to RNFS arrangements. This paper provides a brief overview of the economic analysis framework developed and applied to a model problem of current interest: full-service nuclear fuel leasing arrangements. Furthermore, this paper presents an extended outline of a proposed analysis approach to evaluate the non-proliferation merits of various RNFS alternatives.

Importance of the Donor:Fullerene intermolecular arrangement for high-efficiency organic photovoltaics

KAUST Repository

Graham, Kenneth; Cabanetos, Clement; Jahnke, Justin P.; Idso, Matthew N.; El Labban, Abdulrahman; Ngongang Ndjawa, Guy Olivier; Heumueller, Thomas; Vandewal, Koen; Salleo, Alberto; Chmelka, Bradley F.; Amassian, Aram; Beaujuge, Pierre; McGehee, Michael D.

2014-01-01

The performance of organic photovoltaic (OPV) material systems are hypothesized to depend strongly on the intermolecular arrangements at the donor:fullerene interfaces. A review of some of the most efficient polymers utilized in polymer:fullerene PV devices, combined with an analysis of reported polymer donor materials wherein the same conjugated backbone was used with varying alkyl substituents, supports this hypothesis. Specifically, the literature shows that higher-performing donor-acceptor type polymers generally have acceptor moieties that are sterically accessible for interactions with the fullerene derivative, whereas the corresponding donor moieties tend to have branched alkyl substituents that sterically hinder interactions with the fullerene. To further explore the idea that the most beneficial polymer:fullerene arrangement involves the fullerene docking with the acceptor moiety, a family of benzo[1,2-b:4,5-b]dithiophene-thieno[3,4-c]pyrrole-4,6-dione polymers (PBDTTPD derivatives) was synthesized and tested in a variety of PV device types with vastly different aggregation states of the polymer. In agreement with our hypothesis, the PBDTTPD derivative with a more sterically accessible acceptor moiety and a more sterically hindered donor moiety shows the highest performance in bulk-heterojunction, bilayer, and low-polymer concentration PV devices where fullerene derivatives serve as the electron-accepting materials. Furthermore, external quantum efficiency measurements of the charge-transfer state and solid-state two-dimensional (2D) 13C{1H} heteronuclear correlation (HETCOR) NMR analyses support that a specific polymer:fullerene arrangement is present for the highest performing PBDTTPD derivative, in which the fullerene is in closer proximity to the acceptor moiety of the polymer. This work demonstrates that the polymer:fullerene arrangement and resulting intermolecular interactions may be key factors in determining the performance of OPV material systems

Importance of the Donor:Fullerene intermolecular arrangement for high-efficiency organic photovoltaics

KAUST Repository

Graham, Kenneth

2014-07-09

The performance of organic photovoltaic (OPV) material systems are hypothesized to depend strongly on the intermolecular arrangements at the donor:fullerene interfaces. A review of some of the most efficient polymers utilized in polymer:fullerene PV devices, combined with an analysis of reported polymer donor materials wherein the same conjugated backbone was used with varying alkyl substituents, supports this hypothesis. Specifically, the literature shows that higher-performing donor-acceptor type polymers generally have acceptor moieties that are sterically accessible for interactions with the fullerene derivative, whereas the corresponding donor moieties tend to have branched alkyl substituents that sterically hinder interactions with the fullerene. To further explore the idea that the most beneficial polymer:fullerene arrangement involves the fullerene docking with the acceptor moiety, a family of benzo[1,2-b:4,5-b]dithiophene-thieno[3,4-c]pyrrole-4,6-dione polymers (PBDTTPD derivatives) was synthesized and tested in a variety of PV device types with vastly different aggregation states of the polymer. In agreement with our hypothesis, the PBDTTPD derivative with a more sterically accessible acceptor moiety and a more sterically hindered donor moiety shows the highest performance in bulk-heterojunction, bilayer, and low-polymer concentration PV devices where fullerene derivatives serve as the electron-accepting materials. Furthermore, external quantum efficiency measurements of the charge-transfer state and solid-state two-dimensional (2D) 13C{1H} heteronuclear correlation (HETCOR) NMR analyses support that a specific polymer:fullerene arrangement is present for the highest performing PBDTTPD derivative, in which the fullerene is in closer proximity to the acceptor moiety of the polymer. This work demonstrates that the polymer:fullerene arrangement and resulting intermolecular interactions may be key factors in determining the performance of OPV material systems

12 CFR 714.2 - What are the permissible leasing arrangements?

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 6 2010-01-01 2010-01-01 false What are the permissible leasing arrangements? 714.2 Section 714.2 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING... leasing. In direct leasing, you purchase personal property from a vendor, becoming the owner of the...

46 CFR 108.540 - Survival craft muster and embarkation arrangements.

Science.gov (United States)

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Survival craft muster and embarkation arrangements. 108... OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Lifesaving Equipment § 108.540 Survival craft muster and... craft muster station and embarkation station for a survival craft which is boarded before it is launched...

Seed quality and optimal spatial arrangement of fodder radish

Directory of Open Access Journals (Sweden)

Andréa dos Santos Oliveira

2011-08-01

Full Text Available Besides the use of fodder radish (Raphanus sativus var. oleiferus Metzg. as green manure plant cover crops and animal feed, the seeds have high oil content and low viscosity, ideal characteristics for the production of biodiesel. Studies related to the technology of seed production for this species are insufficient to define the best spatial arrangement of plants in the field that provides higher yields associated with high-quality seeds. Thus, we investigated the space and density between plants that would be ideal for the production of high quality fodder radish seeds. We evaluated the agronomic characteristics and physical, physiological and seed health quality in recently harvested fodder radish in row spacings of 0.2, 0.4, 0.6, and 0.8 m and densities of 10, 30, 50 and 70 seeds m-2. The quality and productivity of the fodder radish's seeds were affected by the spatial arrangement of plants in the field. Seeds harvested under the spacing of 0.2 m and density of 30 seeds m-2 had better performance and physical, physiological and health quality. Alternaria sp. incidence increased with greater spacing, while Fusarium sp. incidence decreased.

Frontex Working Arrangements: Legitimacy and Human Rights Concerns Regarding ‘Technical Relationships’

Directory of Open Access Journals (Sweden)

Melanie Fink

2012-06-01

Full Text Available Practices of extraterritorialisation have become cornerstones of the European Union member states' border control. Most of them are highly dependent on the willingness of third countries to cooperate. An increasingly important phenomenon is that cooperation is secured through relationships established by administrative authorities. This article deals with the challenges arising from the active engagement of Frontex in setting up cooperation structures.It is argued that the so-called working arrangements concluded between Frontex and the respective authorities of third countries, in their current form, show considerable deficiencies from the perspectives of the rule of law, democracy and human rights protection. They are not open to judicial review, the Parliament is not involved in their conclusion and they are not disclosed to the public. Furthermore, the human rights record of cooperating authorities is not considered. Concerns in this respect are frequently attempted to be dispelled by recourse to the 'technical' as opposed to 'political' nature of working arrangements. Likewise, it is assumed that merely 'technical relationships' cannot affect individuals. These arguments are not convincing. Quite the contrary, the political implications of working arrangements and their operation in a highly human rights sensitive field demand conformity with the fundamental values the European Union is based on.

Gas turbine structural mounting arrangement between combustion gas duct annular chamber and turbine vane carrier

Science.gov (United States)

Wiebe, David J.; Charron, Richard C.; Morrison, Jay A.

2016-10-18

A gas turbine engine ducting arrangement (10), including: an annular chamber (14) configured to receive a plurality of discrete flows of combustion gases originating in respective can combustors and to deliver the discrete flows to a turbine inlet annulus, wherein the annular chamber includes an inner diameter (52) and an outer diameter (60); an outer diameter mounting arrangement (34) configured to permit relative radial movement and to prevent relative axial and circumferential movement between the outer diameter and a turbine vane carrier (20); and an inner diameter mounting arrangement (36) including a bracket (64) secured to the turbine vane carrier, wherein the bracket is configured to permit the inner diameter to move radially with the outer diameter and prevent axial deflection of the inner diameter with respect to the outer diameter.

Design of Knowledge Bases for Plant Gene Regulatory Networks.

Science.gov (United States)

Mukundi, Eric; Gomez-Cano, Fabio; Ouma, Wilberforce Zachary; Grotewold, Erich

2017-01-01

Developing a knowledge base that contains all the information necessary for the researcher studying gene regulation in a particular organism can be accomplished in four stages. This begins with defining the data scope. We describe here the necessary information and resources, and outline the methods for obtaining data. The second stage consists of designing the schema, which involves defining the entire arrangement of the database in a systematic plan. The third stage is the implementation, defined by actualization of the database by using software according to a predefined schema. The final stage is development, where the database is made available to users in a web-accessible system. The result is a knowledgebase that integrates all the information pertaining to gene regulation, and which is easily expandable and transferable.

Neuropsychological functioning of an Asperger child with exceptional skill in arranging picture stories.

Science.gov (United States)

Conson, Massimiliano; Salzano, Sara; Grossi, Dario

2011-08-01

A striking special ability in arranging picture stories was reported in an Asperger child (C.M.) showing an exceptional performance on Wechsler picture arrangement subtest. Neuropsychological examination did not disclose visuoperceptual and spatial defects, or working memory, attention and executive disorders, but revealed an attentional bias towards local details of complex structures. A specific assessment of C.M.'s understanding of picture stories demonstrated that, with respect to normal controls, he showed an enhanced ability to detect causal links among elements of a story. These findings provide support to the hypothesis that savantism can be related to strong systemizing in autism.

Governance challenges of cocoa partnership projects in Indonesia: seeking synergy in multi-stakeholder arrangements for sustainable agriculture

NARCIS (Netherlands)

Wijaya, A.; Glasbergen, P.; Leroy, P.; Darmastuti, A.

2018-01-01

This paper investigates multi-stakeholder arrangements initiated by businesses and NGOs from the North that aim to enhance a more sustainable agricultural production at specific localities in Southern countries. We aim to better understand the search for concerted action in multi-actor arrangements.

BEPS Action 2: Neutralizing the Effects on Hybrid Mismatch Arrangements

NARCIS (Netherlands)

de Boer, R.; Marres, O.

2015-01-01

Curbing tax arbitrage is one of the main priorities of the Organization for Economic Cooperation and Development (OECD) (endorsed by the G20 and the G8) ever since the public debate on base erosion fully erupted. Neutralizing the effect of hybrid mismatch arrangements has become Action No. 2 of the

Nuclear yield determinations using isotope-separator-on-line arrangements

International Nuclear Information System (INIS)

Rudstam, G.

1975-01-01

The delay between the formation of a nuclear reaction product and its collection in front of measuring equipment in ISOL arrangements using integrated target-ion source systems has been analyzed. It is shown that a typical delay function takes the form const x (1-esup(-γt))esup(-μt) with γ >> μ. The results can be used for decay corrections in nuclear yield determinations. (Auth.)

Radial arrangement of Janus-like setae permits friction control in spiders.

Science.gov (United States)

Wolff, Jonas O; Gorb, Stanislav N

2013-01-01

Dynamic attachment is the key to move on steep surfaces, with mechanisms being still not well understood. The hunting spider Cupiennius salei (Arachnida, Ctenidae) possesses hairy attachment pads (claw tufts) at its distal legs, consisting of directional branched setae. The morphological investigation revealed that adhesive setae are arranged in a radial manner within the distal tarsus. Friction of claw tufts on smooth glass was measured to reveal the functional effect of seta arrangement within the pad. Measurements revealed frictional anisotropy in both longitudinal and transversal directions. Contact behaviour of adhesive setae was investigated in a reflection interference contrast microscope (RICM). Observations on living spiders showed, that only a small part of the hairy pads is in contact at the same time. Thus the direction of frictional forces is depending on leg placement and rotation. This may aid controlling the attachment to the substrate.

Spatial expression of Hox cluster genes in the ontogeny of a sea urchin

Science.gov (United States)

Arenas-Mena, C.; Cameron, A. R.; Davidson, E. H.

2000-01-01

The Hox cluster of the sea urchin Strongylocentrous purpuratus contains ten genes in a 500 kb span of the genome. Only two of these genes are expressed during embryogenesis, while all of eight genes tested are expressed during development of the adult body plan in the larval stage. We report the spatial expression during larval development of the five 'posterior' genes of the cluster: SpHox7, SpHox8, SpHox9/10, SpHox11/13a and SpHox11/13b. The five genes exhibit a dynamic, largely mesodermal program of expression. Only SpHox7 displays extensive expression within the pentameral rudiment itself. A spatially sequential and colinear arrangement of expression domains is found in the somatocoels, the paired posterior mesodermal structures that will become the adult perivisceral coeloms. No such sequential expression pattern is observed in endodermal, epidermal or neural tissues of either the larva or the presumptive juvenile sea urchin. The spatial expression patterns of the Hox genes illuminate the evolutionary process by which the pentameral echinoderm body plan emerged from a bilateral ancestor.

Occurrence of integrons and antimicrobial resistance genes among Salmonella enterica from Brazil

DEFF Research Database (Denmark)

Peirano, G.; Agersø, Yvonne; Aarestrup, Frank Møller

2006-01-01

= 13) sources. The gene cassette arrangements could be determined in 51 of the positive isolates, which harboured one [dfrA22, aadA1 or orf3 (putative trimethoprim resistance)], two [aadA1-dfrA1, aac(6)-lb-orf1 (unknown function) or aacA4-aadA1], three [dfrA15b-cmlA4-aadA2, orf2 (unknown function......Objectives: To determine the occurrence of antimicrobial resistance genes and role of integrons among 135 anti microbial-resistant Salmonella enterica from Brazil. Methods: The presence of antimicrobial resistance genes, class 1 and 2 integrons and gene cassettes was analysed by PCR and sequencing....... The genetic location of class 1 integrons was determined in 25 isolates by hybridization and plasmid transfer experiments. Results: Fifty-five of the isolates were positive for class I integrons. Integron-positive isolates represented 17 different serovars and were mainly from human (n = 28) and animal (n...

Roles of bHLH genes in neural stem cell differentiation

International Nuclear Information System (INIS)

Kageyama, Ryoichiro; Ohtsuka, Toshiyuki; Hatakeyama, Jun; Ohsawa, Ryosuke

2005-01-01

Neural stem cells change their characteristics over time during development: they initially proliferate only and then give rise to neurons first and glial cells later. In the absence of the repressor-type basic helix-loop-helix (bHLH) genes Hes1, Hes3 and Hes5, neural stem cells do not proliferate sufficiently but prematurely differentiate into neurons and become depleted without making the later born cell types such as astrocytes and ependymal cells. Thus, Hes genes are essential for maintenance of neural stem cells to make cells not only in correct numbers but also in full diversity. Hes genes antagonize the activator-type bHLH genes, which include Mash1, Math and Neurogenin. The activator-type bHLH genes promote the neuronal fate determination and induce expression of Notch ligands such as Delta. These ligands activate Notch signaling and upregulate Hes1 and Hes5 expression in neighboring cells, thereby maintaining these cells undifferentiated. Thus, the activator-type and repressor-type bHLH genes regulate each other, allowing only subsets of cells to undergo differentiation while keeping others to stay neural stem cells. This regulation is essential for generation of complex brain structures of appropriate size, shape and cell arrangement

Assessing School Readiness for a Practice Arrangement Using Decision Tree Methodology.

Science.gov (United States)

Barger, Sara E.

1998-01-01

Questions in a decision-tree address mission, faculty interest, administrative support, and practice plan as a way of assessing arrangements for nursing faculty's clinical practice. Decisions should be based on congruence between the human resource allocation and the reward systems. (SK)

An Investigation of Selective College and University Libraries' Serial Arrangement.

Science.gov (United States)

Kesler, Elizabeth Gates; Teborek, Gay

Data from a survey on serials arrangement procedures and policies at academic libraries was used by the University of Rhode Island (URI) Library in changing current serials policies. Ten libraries, four of which have similar serial holdings and user populations to URI, responded to a questionnaire. Information was obtained on classification versus…

The arrangement of muscle fibers and tendons in two muscles used for growth studies.

OpenAIRE

Stickland, N C

1983-01-01

The arrangement of muscle fibres and tendons was examined in the soleus muscle of rats from 6 to 175 days post partum. The muscle was seen to change from a simple structure, with mean fibre length of approximately 90% of complete muscle length, to a unipennate structure, with mean fibre length of only about 60% of muscle length. The dog pectineus muscle was also investigated and found to have a bipennate structure throughout postnatal growth. The arrangement of muscle fibres in both these mus...

Similar-Case-Based Optimization of Beam Arrangements in Stereotactic Body Radiotherapy for Assisting Treatment Planners

Directory of Open Access Journals (Sweden)

Taiki Magome

2013-01-01

Full Text Available Objective. To develop a similar-case-based optimization method for beam arrangements in lung stereotactic body radiotherapy (SBRT to assist treatment planners. Methods. First, cases that are similar to an objective case were automatically selected based on geometrical features related to a planning target volume (PTV location, PTV shape, lung size, and spinal cord position. Second, initial beam arrangements were determined by registration of similar cases with the objective case using a linear registration technique. Finally, beam directions of the objective case were locally optimized based on the cost function, which takes into account the radiation absorption in normal tissues and organs at risk. The proposed method was evaluated with 10 test cases and a treatment planning database including 81 cases, by using 11 planning evaluation indices such as tumor control probability and normal tissue complication probability (NTCP. Results. The procedure for the local optimization of beam arrangements improved the quality of treatment plans with significant differences (P<0.05 in the homogeneity index and conformity index for the PTV, V10, V20, mean dose, and NTCP for the lung. Conclusion. The proposed method could be usable as a computer-aided treatment planning tool for the determination of beam arrangements in SBRT.

Genomic organization of the rat alpha 2u-globulin gene cluster.

Science.gov (United States)

McFadyen, D A; Addison, W; Locke, J

1999-05-01

The alpha 2u-globulin are a group of similar proteins, belonging to the lipocalin superfamily of proteins, that are synthesized in a subset of secretory tissues in rats. The many alpha 2u-globulin isoforms are encoded by a multigene family that exhibits extensive homology. Despite a high degree of sequence identity, individual family members show diverse expression patterns involving complex hormonal, tissue-specific, and developmental regulation. Analysis suggests that there are approximately 20 alpha 2u-globulin genes in the rat genome. We have used fluorescence in situ hybridization (FISH) to show that the alpha 2u-globulin genes are clustered at a single site on rat Chromosome (Chr) 5 (5q22-24). Southern blots of rat genomic DNA separated by pulsed field gel electrophoresis indicated that the alpha 2u-globulin genes are contained on two NruI fragments with a total size of 880 kbp. Analysis of three P1 clones containing alpha 2u-globulin genes indicated that the alpha 2u-globulin genes are tandemly arranged in a head-to-tail fashion. The organization of the alpha 2u-globulin genes in the rat as a tandem array of single genes differs from the homologous major urinary protein genes in the mouse, which are organized as tandem arrays of divergently oriented gene pairs. The structure of these gene clusters may have consequences for the proposed function, as a pheromone transporter, for the protein products encoded by these genes.

The map-1 gene family in root-knot nematodes, Meloidogyne spp.: a set of taxonomically restricted genes specific to clonal species.

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Iva Tomalova

Full Text Available Taxonomically restricted genes (TRGs, i.e., genes that are restricted to a limited subset of phylogenetically related organisms, may be important in adaptation. In parasitic organisms, TRG-encoded proteins are possible determinants of the specificity of host-parasite interactions. In the root-knot nematode (RKN Meloidogyne incognita, the map-1 gene family encodes expansin-like proteins that are secreted into plant tissues during parasitism, thought to act as effectors to promote successful root infection. MAP-1 proteins exhibit a modular architecture, with variable number and arrangement of 58 and 13-aa domains in their central part. Here, we address the evolutionary origins of this gene family using a combination of bioinformatics and molecular biology approaches. Map-1 genes were solely identified in one single member of the phylum Nematoda, i.e., the genus Meloidogyne, and not detected in any other nematode, thus indicating that the map-1 gene family is indeed a TRG family. A phylogenetic analysis of the distribution of map-1 genes in RKNs further showed that these genes are specifically present in species that reproduce by mitotic parthenogenesis, with the exception of M. floridensis, and could not be detected in RKNs reproducing by either meiotic parthenogenesis or amphimixis. These results highlight the divergence between mitotic and meiotic RKN species as a critical transition in the evolutionary history of these parasites. Analysis of the sequence conservation and organization of repeated domains in map-1 genes suggests that gene duplication(s together with domain loss/duplication have contributed to the evolution of the map-1 family, and that some strong selection mechanism may be acting upon these genes to maintain their functional role(s in the specificity of the plant-RKN interactions.

Experience in arranging shipments of spent fuel assemblies of commercial and research reactors

International Nuclear Information System (INIS)

Komarov, S.; Barinkov, O.; Eshcherkin, A.; Lozhnikov, V.; Smirnov, A.

2008-01-01

At present the key activities of Sosny Company are to inspect physical conditions, handle and arrange shipment of SFA including failed SFA. In 2003 after obtaining the license of Gosatomnadzor (Rostechnadzor now) entitled to handle nuclear materials in the process of their shipment, Sosny Company started preparing certification and arranging SFA shipment on its own. About 40 shipments of SFA were performed with participation of Sosny Company. Experience in handling failed SFA - an example of development of a new technology could be the transport and technological scheme of RBMK-1000 SFA shipment from Leningradskaya NPP that was designed by Sosny Company. TUK-11 cask was selected for this shipment. The example of change of transport and technological scheme is modification of the technology for handling and shipment of WWER-440 SFA from Kola NPP. Experience in arranging transportation - based on the results of development of logistics schemes for shipping SFA of reactor facilities Sosny Company justified and implemented composition of mixed trains containing rail cars of many types that enabled to perform shipment more efficiently in time and cost. Experience in arranging handling and shipment of research reactor SFA - over the past years the activity of Sosny Company was aimed at implementing international Russian Research Reactor Fuel Return (RRRFR) program. Since equipment of the majority of research centers doesn't allow for the large casks to be accepted and loaded, special casks of less mass and dimensions are used to ship SFA from research reactors. In RRRFR program it is assumed to use different casks for RR SFA such as Russian TUK- 19, TUK-128 and foreign SKODA VPVR/M and NAC-LWT. At present Sosny Company is involved in coordination of the efforts of the affected organizations in creating the type 'C' package for RR SFA in the RF. Conclusion: Under conditions of constant increase of the requirements to shipment safety and complication of regulations of all

Circular displays: control/display arrangements and stereotype strength with eight different display locations.

Science.gov (United States)

Chan, Alan H S; Hoffmann, Errol R

2015-01-01

Two experiments are reported that were designed to investigate control/display arrangements having high stereotype strengths when using circular displays. Eight display locations relative to the operator and control were tested with rotational and translational controls situated on different planes according to the Frame of Reference Transformation Tool (FORT) model of Wickens et al. (2010). (Left. No, Right! Development of the Frame of Reference Transformation Tool (FORT), Proceedings of the Human Factors and Ergonomics Society 54th Annual Meeting, 54: 1022-1026). In many cases, there was little effect of display locations, indicating the importance of the Worringham and Beringer (1998. Directional stimulus-response compatibility: a test of three alternative principles. Ergonomics, 41(6), 864-880) Visual Field principle and an extension of this principle for rotary controls (Hoffmann and Chan (2013). The Worringham and Beringer 'visual field' principle for rotary controls. Ergonomics, 56(10), 1620-1624). The initial indicator position (12, 3, 6 and 9 o'clock) had a major effect on control/display stereotype strength for many of the six controls tested. Best display/control arrangements are listed for each of the different control types (rotational and translational) and for the planes on which they are mounted. Data have application where a circular display is used due to limited display panel space and applies to space-craft, robotics operators, hospital equipment and home appliances. Practitioner Summary: Circular displays are often used when there is limited space available on a control panel. Display/control arrangements having high stereotype strength are listed for four initial indicator positions. These arrangements are best for design purposes.

A Circularly Arranged Sextuple Triptycene Gear Molecule.

Science.gov (United States)

Ube, Hitoshi; Yamada, Ryo; Ishida, Jun-Ichi; Sato, Hiroyasu; Shiro, Motoo; Shionoya, Mitsuhiko

2017-11-22

Herein we report the synthesis of a circularly arranged sextuple triptycene gear molecule, hexakis(10-dodecyloxy-9-triptycyl)ethynylbenzene, via the trimerization of the corresponding triyne with a cobalt catalyst. The six triptycene gears are closely engaged with each other as confirmed by single crystal X-ray structure analysis, and their motion in solution was established by NMR spectroscopy. Notably, when one bulky RuCp* complex was attached to one triptycene gear, the whole movement of the six gears was highly restricted via their mechanical engagement. Development of such a multigear molecule would provide a structural basis for molecular motion transmission systems with a switching function.

Mithra and the Arrangement of Geographical Lists in the Achaemenid and Sasanid Inscriptions

Directory of Open Access Journals (Sweden)

nazanin tamari

2016-12-01

Full Text Available The division of the world is one of the issues that began with the social life of human in all over the world and still continues. The oldest division has mythical and legendary aspects that shows the geographical knowledge or religious and ethnic beliefs of their predecessors. Various geographical divisions can be seen in the ancient Iranians tradition. Each of these divisions follow the specific arrangement of listing the geographical areas, which discussed in this paper. The arrangement of geographical areas in Achaemenid and Sasanin inscriptions and in the Mihr Ya&scaront, the oldest of Avesta, are the same. Because of this similarity can’t be accidental, in this paper the cause of the similarities has been investigated. The arrangement of geographical areas in two lists ( inscriptions and Mihr Ya&scaront shows clockwise (sunwise fashion, that investigated in religious view in this study. Due to the Mithra’s influence on cultural and religious context of the ancient Iranians, for the first time in present paper investigated the role of this god and his influence on the writing the geographical lists in the Achaemenid and Sasanin inscriptions.

Nuclear topography and expression of the BCR/ABL fusion gene and its protein level influenced by cell differentiation and RNA interference

Czech Academy of Sciences Publication Activity Database

Bártová, Eva; Harničarová, Andrea; Pacherník, Jiří; Kozubek, Stanislav

2005-01-01

Roč. 29, č. 8 (2005), s. 901-913 ISSN 0145-2126 R&D Projects: GA AV ČR(CZ) 1QS500040508; GA ČR(CZ) GA202/04/0907; GA MZd NC6987; GA AV ČR(CZ) IAA5004306; GA MŠk(CZ) LC535 Institutional research plan: CEZ:AV0Z50040507 Keywords : BCR /ABL fusion gene * chromatin arrangement * gene expression Subject RIV: BO - Biophysics Impact factor: 2.372, year: 2005

CODAC systems arrangement and connectivity

Energy Technology Data Exchange (ETDEWEB)

Gulati, Hitesh Kumar, E-mail: hkgulati@gmail.com; Beltran, David; Kuehn, Ingo; Kotamaki, Miikka; Makijarvi, Petri; Wallander, Anders

2013-10-15

termination point for CODAC Network infrastructure. The CODAC Network cables running from the nearest CODAC Network hutch will terminate in these panels. Network panels are installed at strategic locations close to plant system I and C cubicles. This paper will describe more details about the physical arrangement of CODAC systems in different buildings on ITER platform for different purpose and their planned connectivity. This paper will also provide more information about the volume allocations for CODAC components, planned cabling arrangement and other infrastructure requirements like electrical and cooling etc.

Contractual arrangements and food quality certifications in the Mexican avocado industry

NARCIS (Netherlands)

Arana-Coronado, J.J.; Bijman, J.; Omta, S.W.F.; Oude Lansink, A.G.J.M.

2013-01-01

The adoption of private quality certifications in agrifood supply chains often requires specific investments by producers which can be safeguarded by choosing specific contractual arrangements. Based on a survey data from avocado producers in Mexico, this paper aims to analyze the impact of

Weddings and war: marriage arrangements and celebrations in two Palestinian intifadas

NARCIS (Netherlands)

Johnson, P.; Abu Nahleh, L.; Moors, A.

2009-01-01

In our comparison of marriage arrangements and wedding celebrations during the first and the second intifada in Palestine, we focus on "political marriages" wherein the political activism and affiliation of the marital partners are of considerable importance. During the first intifada, political

Gene expression profile analysis of Ligon lintless-1 (Li1) mutant reveals important genes and pathways in cotton leaf and fiber development.

Science.gov (United States)

Ding, Mingquan; Jiang, Yurong; Cao, Yuefen; Lin, Lifeng; He, Shae; Zhou, Wei; Rong, Junkang

2014-02-10

Ligon lintless-1 (Li1) is a monogenic dominant mutant of Gossypium hirsutum (upland cotton) with a phenotype of impaired vegetative growth and short lint fibers. Despite years of research involving genetic mapping and gene expression profile analysis of Li1 mutant ovule tissues, the gene remains uncloned and the underlying pathway of cotton fiber elongation is still unclear. In this study, we report the whole genome-level deep-sequencing analysis of leaf tissues of the Li1 mutant. Differentially expressed genes in leaf tissues of mutant versus wild-type (WT) plants are identified, and the underlying pathways and potential genes that control leaf and fiber development are inferred. The results show that transcription factors AS2, YABBY5, and KANDI-like are significantly differentially expressed in mutant tissues compared with WT ones. Interestingly, several fiber development-related genes are found in the downregulated gene list of the mutant leaf transcriptome. These genes include heat shock protein family, cytoskeleton arrangement, cell wall synthesis, energy, H2O2 metabolism-related genes, and WRKY transcription factors. This finding suggests that the genes are involved in leaf morphology determination and fiber elongation. The expression data are also compared with the previously published microarray data of Li1 ovule tissues. Comparative analysis of the ovule transcriptomes of Li1 and WT reveals that a number of pathways important for fiber elongation are enriched in the downregulated gene list at different fiber development stages (0, 6, 9, 12, 15, 18dpa). Differentially expressed genes identified in both leaf and fiber samples are aligned with cotton whole genome sequences and combined with the genetic fine mapping results to identify a list of candidate genes for Li1. Copyright © 2013 Elsevier B.V. All rights reserved.

Governance arrangements for health systems in low-income countries: an overview of systematic reviews.

Science.gov (United States)

Herrera, Cristian A; Lewin, Simon; Paulsen, Elizabeth; Ciapponi, Agustín; Opiyo, Newton; Pantoja, Tomas; Rada, Gabriel; Wiysonge, Charles S; Bastías, Gabriel; Garcia Marti, Sebastian; Okwundu, Charles I; Peñaloza, Blanca; Oxman, Andrew D

2017-09-12

Governance arrangements include changes in rules or processes that determine authority and accountability for health policies, organisations, commercial products and health professionals, as well as the involvement of stakeholders in decision-making. Changes in governance arrangements can affect health and related goals in numerous ways, generally through changes in authority, accountability, openness, participation and coherence. A broad overview of the findings of systematic reviews can help policymakers, their technical support staff and other stakeholders to identify strategies for addressing problems and improving the governance of their health systems. To provide an overview of the available evidence from up-to-date systematic reviews about the effects of governance arrangements for health systems in low-income countries. Secondary objectives include identifying needs and priorities for future evaluations and systematic reviews on governance arrangements and informing refinements of the framework for governance arrangements outlined in the overview. We searched Health Systems Evidence in November 2010 and PDQ Evidence up to 17 December 2016 for systematic reviews. We did not apply any date, language or publication status limitations in the searches. We included well-conducted systematic reviews of studies that assessed the effects of governance arrangements on patient outcomes (health and health behaviours), the quality or utilisation of healthcare services, resource use (health expenditures, healthcare provider costs, out-of-pocket payments, cost-effectiveness), healthcare provider outcomes (such as sick leave), or social outcomes (such as poverty, employment) and that were published after April 2005. We excluded reviews with limitations that were important enough to compromise the reliability of the findings of the review. Two overview authors independently screened reviews, extracted data and assessed the certainty of evidence using GRADE. We prepared

African American college women: constructing a hierarchy of sexual arrangements.

Science.gov (United States)

Foreman, F E

2003-08-01

The purpose of this study was to understand and describe the safer sex decision-making processes of a group of African American college women. The study participants consisted of 15 women aged 19 to 33, who were full-time students attending a four-year university in Texas. The women self-identified as having been sexually active with at least one male partner within the past year. Semi-structured in-depth interviews lasting approximately 1.5 hours provided data. Theme and domain analysis of the interviews and field notes revealed that women employed both emotional and philosophical strategies to determine their safer sex behaviour. These strategies involved the use of a 'self-defined' sexual arrangements hierarchy. This hierarchy served to define the way women ordered and valued different types of sexual arrangement, from casual to committed. The resulting hierarchy also guided the safer sex behaviour of these women. The implications for intervention programmes that are targeted at increasing safer sex behaviour and HIV risk reduction are discussed in light of these findings.

An ancient history of gene duplications, fusions and losses in the evolution of APOBEC3 mutators in mammals

Science.gov (United States)

2012-01-01

Background The APOBEC3 (A3) genes play a key role in innate antiviral defense in mammals by introducing directed mutations in the DNA. The human genome encodes for seven A3 genes, with multiple splice alternatives. Different A3 proteins display different substrate specificity, but the very basic question on how discerning self from non-self still remains unresolved. Further, the expression of A3 activity/ies shapes the way both viral and host genomes evolve. Results We present here a detailed temporal analysis of the origin and expansion of the A3 repertoire in mammals. Our data support an evolutionary scenario where the genome of the mammalian ancestor encoded for at least one ancestral A3 gene, and where the genome of the ancestor of placental mammals (and possibly of the ancestor of all mammals) already encoded for an A3Z1-A3Z2-A3Z3 arrangement. Duplication events of the A3 genes have occurred independently in different lineages: humans, cats and horses. In all of them, gene duplication has resulted in changes in enzyme activity and/or substrate specificity, in a paradigmatic example of convergent adaptive evolution at the genomic level. Finally, our results show that evolutionary rates for the three A3Z1, A3Z2 and A3Z3 motifs have significantly decreased in the last 100 Mya. The analysis constitutes a textbook example of the evolution of a gene locus by duplication and sub/neofunctionalization in the context of virus-host arms race. Conclusions Our results provide a time framework for identifying ancestral and derived genomic arrangements in the APOBEC loci, and to date the expansion of this gene family for different lineages through time, as a response to changes in viral/retroviral/retrotransposon pressure. PMID:22640020

Strengthening ASEAN+3 Regional Financial Arrangements: A New Framework Beyond CMIM

Directory of Open Access Journals (Sweden)

Young-Joon Park

2017-03-01

Full Text Available This paper examines the operational limitations of the Chiang Mai Initiative Multilateralization (CMIM as a regional financial safety net in East Asia and presents a new regional financial arrangement. To overcome the drawbacks of the Chiang Mai Initiative Multilateralization which has never been activated so far, this study proposes that ASEAN+3 establish a new lending facility, so-called a Reserve Fund Facility, and create a regional common reserves asset. The proposed Reserve Fund Facility framework guarantees lending automaticity of the liquidity facility, based on upfront funding instead of pledge funding. Establishing the Reserve Fund Facility could find a way of making up for weakness of the Chiang Mai Initiative Multilateralization and responding to the regional needs for effective regional financial arrangement. The full-fledged Reserve Fund Facility will ultimately contribute to the future development of East Asia's monetary and financial cooperation beyond the Chiang Mai Initiative Multilateralization.

DNA context represents transcription regulation of the gene in mouse embryonic stem cells

Science.gov (United States)

Ha, Misook; Hong, Soondo

2016-04-01

Understanding gene regulatory information in DNA remains a significant challenge in biomedical research. This study presents a computational approach to infer gene regulatory programs from primary DNA sequences. Using DNA around transcription start sites as attributes, our model predicts gene regulation in the gene. We find that H3K27ac around TSS is an informative descriptor of the transcription program in mouse embryonic stem cells. We build a computational model inferring the cell-type-specific H3K27ac signatures in the DNA around TSS. A comparison of embryonic stem cell and liver cell-specific H3K27ac signatures in DNA shows that the H3K27ac signatures in DNA around TSS efficiently distinguish the cell-type specific H3K27ac peaks and the gene regulation. The arrangement of the H3K27ac signatures inferred from the DNA represents the transcription regulation of the gene in mESC. We show that the DNA around transcription start sites is associated with the gene regulatory program by specific interaction with H3K27ac.

Molecular patterns of X chromosome-linked color vision genes among 134 menof European ancestry

International Nuclear Information System (INIS)

Drummond-Borg, M.; Deeb, S.S.; Motulsky, A.G.

1989-01-01

The authors used Southern blot hybridization to study X chromosome-linked color vision genes encoding the apoproteins of red and green visual pigments in 134 unselected Caucasian men. One hundred and thirteen individuals (84.3%) had a normal arrangement of their color vision pigment genes. All had one red pigment gene; the number of green pigment genes ranged from one to five with a mode of two. The frequency of molecular genotypes indicative of normal color vision (84.3%) was significantly lower than had been observed in previous studies of color vision phenotypes. Color vision defects can be due to deletions of red or green pigment genes or due to formation of hybrid genes comprising portions of both red and green pigment genes. Characteristic anomalous patterns were seen in 15 (11.2%) individuals: 7 (5.2%) had patterns characteristic of deuteranomaly, 2 (1.5%) had patterns characteristic of deuteranopia, and 6 (4.5%) had protan patterns. Previously undescribed hybrid gene patterns consisting of both green and red pigment gene fragments in addition to normal red and green genes were observed in another 6 individuals (4.5%). Thus, DNA testing detected anomalous color vision pigment genes at a higher frequency than expected from phenotypic color vision tests

Optimal needle arrangement for intraoperative planning in permanent I-125 prostate implants

International Nuclear Information System (INIS)

Thompson, S.A.; Fung, A.Y.C.; Zaider, M.

2002-01-01

One limitation of intraoperative planning of permanent prostate implants is that needles must already be in the gland before planning images are acquired. Improperly placed needles often restrict the capability of generating optimal seed placement. We developed guiding principles for the proper layout of needles within the treatment volume. The Memorial Sloan-Kettering Cancer Center planning system employs a genetic algorithm to find the optimal seed implantation pattern consistent with pre-assigned constraints (needle geometry, uniformity, conformity and the avoidance of high doses to urethra and rectum). Ultrasound volumes for twelve patients with I-125 implants were used to generate six plans per patient (total 72 plans) with different needle arrangements. The plans were evaluated in terms of V100 (percentage prostate volume receiving at least the prescription dose), U135 (percentage urethra volume receiving at least 135% of prescription dose), and CI (conformity index, the ratio of treatment volume to prescription dose volume.) The method termed POSTCTR, in which needles were placed on the periphery of the largest ultrasound slice and posterior central needles were placed as needed, consistently gave superior results for all prostate sizes. Another arrangement, labelled POSTLAT, where the needles were placed peripherally with additional needles in the posterior lateral lobes, also gave satisfactory results. We advocate two needle arrangements, POSTCTR and POSTLAT, with the former giving better results. (author)

Optimal needle arrangement for intraoperative planning in permanent I-125 prostate implants

Energy Technology Data Exchange (ETDEWEB)

Thompson, S.A. [Department of Medical Physics, North Shore-Long Island Jewish Health System, Manhassett, NY (United States); Fung, A.Y.C.; Zaider, M. [Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, NY (United States)

2002-08-21

One limitation of intraoperative planning of permanent prostate implants is that needles must already be in the gland before planning images are acquired. Improperly placed needles often restrict the capability of generating optimal seed placement. We developed guiding principles for the proper layout of needles within the treatment volume. The Memorial Sloan-Kettering Cancer Center planning system employs a genetic algorithm to find the optimal seed implantation pattern consistent with pre-assigned constraints (needle geometry, uniformity, conformity and the avoidance of high doses to urethra and rectum). Ultrasound volumes for twelve patients with I-125 implants were used to generate six plans per patient (total 72 plans) with different needle arrangements. The plans were evaluated in terms of V100 (percentage prostate volume receiving at least the prescription dose), U135 (percentage urethra volume receiving at least 135% of prescription dose), and CI (conformity index, the ratio of treatment volume to prescription dose volume.) The method termed POSTCTR, in which needles were placed on the periphery of the largest ultrasound slice and posterior central needles were placed as needed, consistently gave superior results for all prostate sizes. Another arrangement, labelled POSTLAT, where the needles were placed peripherally with additional needles in the posterior lateral lobes, also gave satisfactory results. We advocate two needle arrangements, POSTCTR and POSTLAT, with the former giving better results. (author)

Tele-Coupling Energy Efficiency Polices in Europe: Showcasing the German Governance Arrangements

Directory of Open Access Journals (Sweden)

Marc Ringel

2018-05-01

Full Text Available Climate change entails many situations of tele-coupling. We analyze an example in the field of European climate and energy policy. The EU aims at an almost full decarbonisation of its economy by 2050. Achieving this objective asks for transforming the energy sectors of EU Member States. These are responsible for 80% of carbon emissions. Further to this policy coupling, the EU transformation objectives have to be implemented by the Member States, regions and local actors. This proves especially complex in the field of energy efficiency. Here, a variety of policy instruments and actors are in place. In our contribution, we investigate in the question how multi-level governance arrangements in the energy efficiency field are designed. We focus on Germany as example for a federal state setting. Our review method comprises literature content analysis, primary sources, expert interviews and an in-depth screening of the German Sustainable Energy Action Plans. We find that formal vertical coordination has been successfully backed up by horizontal and especially informal governance mechanisms, leading to a model of polycentric governance. This model might serve as blueprint for other multi-level governance arrangements. Yet, we find that the “last mile” of this coordination still needs strengthening: Local actors need more active engaging and empowering to reap the full potential of the governance arrangements.

Spatial arrangements affect suppression of invasive Alternanthera philoxeroides by native Hemarthria compressa

Science.gov (United States)

Liao, Jianxiong; Tao, Min; Jiang, Mingxi

2014-08-01

It has been hypothesized that differences in spatial arrangements change the relative frequency of intra- and interspecific encounters between plant species. Manipulating spatial arrangement may play a role in invasive plant suppression when native species are used as competitors against introduced species. In this study, a replacement series experiment was performed to investigate the effects of intraspecifically random and aggregated spatial arrangements on interactions between the native plant Hemarthria compressa and the invasive plant Alternanthera philoxeroides, to test the possibility and effectiveness of H. compressa in suppressing A. philoxeroides. When both species were planted in intraspecifically random spatial patterns, H. compressa had a competitive advantage over A. philoxeroides at relative densities of 2:2 and 3:1. However, aggregation increased the strength, and therefore the cost, of intraspecific competition in H. compressa, resulting in lower biomass production, which reduced its effectiveness as an interspecific competitor. As the relative density of H. compressa in mixtures decreased, plants allocated more biomass to belowground parts, but fewer interspecific encounters lowered its inhibitory effects on A. philoxeroides. The results not only confirm that the frequency of conspecific and heterospecific encounters can influence competitive outcomes, but also suggest that a reduction in the degree of spatial aggregation in H. compressa and an increase in its relative densities may be essential to increase the suppression of A. philoxeroides.

12 CFR 714.8 - Are the early payment provisions, or interest rate provisions, applicable in leasing arrangements?

Science.gov (United States)

2010-01-01

... provisions, or interest rate provisions, applicable in leasing arrangements? You are not subject to the early... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Are the early payment provisions, or interest rate provisions, applicable in leasing arrangements? 714.8 Section 714.8 Banks and Banking NATIONAL...

Effects of Symmetrically Arranged Heat Sources on the Heat Release Performance of Extruded-Type Heat Sinks

Energy Technology Data Exchange (ETDEWEB)

Ku, Min Ye [Chonbuk National Univ., Chonju (Korea, Republic of)

2016-02-15

In this study we investigated the effects of symmetrically arranged heat sources on the heat release performances of extruded-type heat sinks through experiments and thermal fluid simulations. Also, based on the results we suggested a high-efficiency and cost-effective heat sink for a solar inverter cooling system. In this parametric study, the temperatures between heaters on the base plate and the heat release rates were investigated with respect to the arrangements of heat sources and amounts of heat input. Based on the results we believe that the use of both sides of the heat sink is the preferred method for releasing the heat from the heat source to the ambient environment rather than the use of a single side of the heat sink. Also from the results, it is believed that the symmetric arrangement of the heat sources is recommended to achieve a higher rate of heat transfer. From the results of the thermal fluid simulation, it was possible to confirm the qualitative agreement with the experimental results. Finally, quantitative comparison with respect to mass flow rates, heat inputs, and arrangements of the heat source was also performed.

Geospatial Characterization of Fluvial Wood Arrangement in a Semi-confined Alluvial River

Science.gov (United States)

Martin, D. J.; Harden, C. P.; Pavlowsky, R. T.

2014-12-01

Large woody debris (LWD) has become universally recognized as an integral component of fluvial systems, and as a result, has become increasingly common as a river restoration tool. However, "natural" processes of wood recruitment and the subsequent arrangement of LWD within the river network are poorly understood. This research used a suite of spatial statistics to investigate longitudinal arrangement patterns of LWD in a low-gradient, Midwestern river. First, a large-scale GPS inventory of LWD, performed on the Big River in the eastern Missouri Ozarks, resulted in over 4,000 logged positions of LWD along seven river segments that covered nearly 100 km of the 237 km river system. A global Moran's I analysis indicates that LWD density is spatially autocorrelated and displays a clustering tendency within all seven river segments (P-value range = 0.000 to 0.054). A local Moran's I analysis identified specific locations along the segments where clustering occurs and revealed that, on average, clusters of LWD density (high or low) spanned 400 m. Spectral analyses revealed that, in some segments, LWD density is spatially periodic. Two segments displayed strong periodicity, while the remaining segments displayed varying degrees of noisiness. Periodicity showed a positive association with gravel bar spacing and meander wavelength, although there were insufficient data to statistically confirm the relationship. A wavelet analysis was then performed to investigate periodicity relative to location along the segment. The wavelet analysis identified significant (α = 0.05) periodicity at discrete locations along each of the segments. Those reaches yielding strong periodicity showed stronger relationships between LWD density and the geomorphic/riparian independent variables tested. Analyses consistently identified valley width and sinuosity as being associated with LWD density. The results of these analyses contribute a new perspective on the longitudinal distribution of LWD in

Improvements in or relating to information display arrangements

International Nuclear Information System (INIS)

Blay, A.G.

1975-01-01

An information display arrangement for use in biomedical radiography with either X- or γ-radiation or ultrasonic waves is described. This invention overcomes the drawbacks of conventional three-dimensional displays where certain features may be partially or completely obscured from view by matter which is not of interest. This improvement is achieved by interactive means using a light pen on a cathode ray tube display to effectively draw boundaries between relevant and irrelevant features. The computerised display is then up-dated from the information store containing the transmission data. (U.K.)

Alternate ohmic heating coil arrangements for compact tokamak

International Nuclear Information System (INIS)

Dawson, J.W.; Moretti, A.; Stevens, H.C.; Thompson, K.

1978-01-01

The results for a number of ohmic heating (OH) coil arrangements which will allow the reduction of the major radius of Experimental Power Reactor (EPR) tokamaks will be given. In each case the results are compared, at least indirectly, to the reference case, which has the OH solenoid inside the central core of the reactor. The goal for the alternate geometries studied was to stay within the requirements imposed by the EPR conditions on the plasma and to produce as much or more OH V-s as the reference case

Mexico; 2013 Review Under the Flexible Credit Line Arrangement

OpenAIRE

International Monetary Fund

2013-01-01

This paper discusses Mexico’ Review Under the Flexible Credit Line (FCL) Arrangement. Significant progress has been made in advancing far-reaching structural reforms, signaling Mexico’s commitment to address deep-rooted impediments to growth. The economy slowed down in early 2013, but is expected to recover starting in the second half of the year. Mexico’s financial markets have functioned reasonably well through the recent global volatility, although with some currency depreciation and a ris...

Correlation between spatial (3D) structure of pea and bean thylakoid membranes and arrangement of chlorophyll-protein complexes.

Science.gov (United States)

Rumak, Izabela; Mazur, Radosław; Gieczewska, Katarzyna; Kozioł-Lipińska, Joanna; Kierdaszuk, Borys; Michalski, Wojtek P; Shiell, Brian J; Venema, Jan Henk; Vredenberg, Wim J; Mostowska, Agnieszka; Garstka, Maciej

2012-05-25

The thylakoid system in plant chloroplasts is organized into two distinct domains: grana arranged in stacks of appressed membranes and non-appressed membranes consisting of stroma thylakoids and margins of granal stacks. It is argued that the reason for the development of appressed membranes in plants is that their photosynthetic apparatus need to cope with and survive ever-changing environmental conditions. It is not known however, why different plant species have different arrangements of grana within their chloroplasts. It is important to elucidate whether a different arrangement and distribution of appressed and non-appressed thylakoids in chloroplasts are linked with different qualitative and/or quantitative organization of chlorophyll-protein (CP) complexes in the thylakoid membranes and whether this arrangement influences the photosynthetic efficiency. Our results from TEM and in situ CLSM strongly indicate the existence of different arrangements of pea and bean thylakoid membranes. In pea, larger appressed thylakoids are regularly arranged within chloroplasts as uniformly distributed red fluorescent bodies, while irregular appressed thylakoid membranes within bean chloroplasts correspond to smaller and less distinguished fluorescent areas in CLSM images. 3D models of pea chloroplasts show a distinct spatial separation of stacked thylakoids from stromal spaces whereas spatial division of stroma and thylakoid areas in bean chloroplasts are more complex. Structural differences influenced the PSII photochemistry, however without significant changes in photosynthetic efficiency. Qualitative and quantitative analysis of chlorophyll-protein complexes as well as spectroscopic investigations indicated a similar proportion between PSI and PSII core complexes in pea and bean thylakoids, but higher abundance of LHCII antenna in pea ones. Furthermore, distinct differences in size and arrangements of LHCII-PSII and LHCI-PSI supercomplexes between species are suggested

Horizontal arrangement of anodes of microbial fuel cells enhances remediation of petroleum hydrocarbon-contaminated soil.

Science.gov (United States)

Zhang, Yueyong; Wang, Xin; Li, Xiaojing; Cheng, Lijuan; Wan, Lili; Zhou, Qixing

2015-02-01

With the aim of in situ bioremediation of soil contaminated by hydrocarbons, anodes arranged with two different ways (horizontal or vertical) were compared in microbial fuel cells (MFCs). Charge outputs as high as 833 and 762C were achieved in reactors with anodes horizontally arranged (HA) and vertically arranged (VA). Up to 12.5 % of the total petroleum hydrocarbon (TPH) was removed in HA after 135 days, which was 50.6 % higher than that in VA (8.3 %) and 95.3 % higher than that in the disconnected control (6.4 %). Hydrocarbon fingerprint analysis showed that the degradation rates of both alkanes and polycyclic aromatic hydrocarbons (PAHs) in HA were higher than those in VA. Lower mass transport resistance in the HA than that of the VA seems to result in more power and more TPH degradation. Soil pH was increased from 8.26 to 9.12 in HA and from 8.26 to 8.64 in VA, whereas the conductivity was decreased from 1.99 to 1.54 mS/cm in HA and from 1.99 to 1.46 mS/cm in VA accompanied with the removal of TPH. Considering both enhanced biodegradation of hydrocarbon and generation of charge in HA, the MFC with anodes horizontally arranged is a promising configuration for future applications.

Method for the removal of a gaseous fluid and arrangement therefore

NARCIS (Netherlands)

Ursem, W.N.J.; Marijnissen, J.C.M.

2011-01-01

The invention provides a method for the removal of a gaseous fluid comprising (a) applying an electric field between a first electrode arranged to generate a corona discharge and a second electrode, comprising a haze-permeable electrically conductive sieve of a plurality of conductive strands, (b)

Measuring Social Competence with the Wechsler Picture Arrangement and Comprehension Subtests.

Science.gov (United States)

Campbell, Jonathan M.; McCord, David M.

1999-01-01

Tested the traditional assumption that the Wechsler Adult Intelligence Scale-Revised and the Wechsler Intelligence Scale for Children-Revised Picture Arrangement and Comprehension subtests are measures of social competence using scores from 136 children and adolescents. Cautions against interpreting either subtest as an indicator of social…

Construction of a restriction map and gene map of the lettuce chloroplast small single-copy region using Southern cross-hybridization.

Science.gov (United States)

Mitchelson, K R

1996-01-01

The small single-copy region (SSCR) of the chloroplast genome of many higher plants typically contain ndh genes encoding proteins that share homology with subunits of the respiratory-chain reduced nicotinamide adenine dinucleotide (NADH) dehydrogenase complex of mitochondria. A map of the lettuce chloroplast SSCR has been determined by Southern cross-hybridization, taking advantage of the high degree of homology between a tobacco small single-copy fragment and a corresponding lettuce chloroplast fragment. The gene order of the SSCR of lettuce and tobacco chloroplasts is similar. The cross-hybridization method can rapidly create a primary gene map of unknown chloroplast fragments, thus providing detailed information of the localization and arrangement of genes and conserved open reading frame regions.

A versatile model for soft patchy particles with various patch arrangements.

Science.gov (United States)

Li, Zhan-Wei; Zhu, You-Liang; Lu, Zhong-Yuan; Sun, Zhao-Yan

2016-01-21

We propose a simple and general mesoscale soft patchy particle model, which can felicitously describe the deformable and surface-anisotropic characteristics of soft patchy particles. This model can be used in dynamics simulations to investigate the aggregation behavior and mechanism of various types of soft patchy particles with tunable number, size, direction, and geometrical arrangement of the patches. To improve the computational efficiency of this mesoscale model in dynamics simulations, we give the simulation algorithm that fits the compute unified device architecture (CUDA) framework of NVIDIA graphics processing units (GPUs). The validation of the model and the performance of the simulations using GPUs are demonstrated by simulating several benchmark systems of soft patchy particles with 1 to 4 patches in a regular geometrical arrangement. Because of its simplicity and computational efficiency, the soft patchy particle model will provide a powerful tool to investigate the aggregation behavior of soft patchy particles, such as patchy micelles, patchy microgels, and patchy dendrimers, over larger spatial and temporal scales.

Arranging and finding folders and files on your Windows 7 computer

CERN Document Server

Steps, Studio Visual

2014-01-01

If you have lots of documents on your desk, it may prove to be impossible to find the document you are looking for. In order to easily find certain documents, they are often stored in a filing cabinet and arranged in a logical order. The folders on your computer serve the same purpose. They do not just contain files; they can also contain other folders. You can create an unlimited number of folders, and each folder can contain any number of subfolders and files. You can use Windows Explorer, also called the folder window, to work with the files and folders on your computer. You can copy, delete, move, find, and sort files, among other things. Or you can transfer files and folders to a USB stick, an external hard drive, a CD, DVD or Blu-Ray disk. In this practical guide we will show you how to use the folder window, and help you arrange your own files.

The Possibility of Vice-Presidents’ Authority Arrangement in the 1945 Constitution through Constitutional Amendment

Directory of Open Access Journals (Sweden)

Fajar L. Suroso

2016-04-01

Full Text Available The debate over the vice-presidents’ authority reappeared in the administration of President Jokowi after the “authority expansion of the Chief of Presidency Staff” and the case of “Rizal Ramli vs Jusuf Kalla”. This article is intended to provide arguments for the idea of some parties to organize more explicit and detailed the authority of vice-president in the 1945 Constitution. The idea arises from the absence of further arrangement on the authority of vice-president in the 1945 Constitution. This article is systematized into 3 (three sub-theme; 1 the arrangement of the vice-presidents’ authority in the constitution for several countries; 2 The authority of the vice-president according to the 1945 Constitution, and 3 New resultant and the possibility of 1945 Constitution amendment. The result revealed a number of interesting things; 1 the constitutions of other countries do not specify the authority of the vice-president and put the vice-president as a “spare tire” when the president is absent; 2 no new resultant about the position and authority of the vice-president so that theoretically is not reason enough to regulate in detail the authority of the vice-president through the 1945 Constitution amendment; 3 arrangement in detail in the authority of vice-president in the 1945 Constitution holds the potential to confuse the presidential system design as the 1945 Constitution. Therefore, the possibility of vice-presidents’ authority arrangement in the 1945 Constitution through amendment is very small, both in terms of momentum and the substance of issues.

Unique morphology and gradient arrangement of nacre's platelets in green mussel shells

Energy Technology Data Exchange (ETDEWEB)

Xu, Jun; Zhang, Gangsheng, E-mail: zhanggs@gxu.edu.cn

2015-07-01

Nacre has long served as a classic model in biomineralization and the synthesis of biomimetic materials. However, the morphology and arrangement of its basic building blocks, the aragonite platelets, are still under hot debate. In this study, using a field emission scanning electron microscope (SEM), a high-resolution transmission electron microscope (HRTEM), and an X-ray diffractometer (XRD), we investigate the platelets at the edges and centers of green mussel shells. We find that 1) flat and curved platelets coexist in green mussel shells; 2) the immature platelets at the shell edge are aggregates of aragonite nanoparticles, whereas the immature ones at the shell center are single crystals; and 3) the morphology and thickness of the platelets exhibit a gradient arrangement. Based on these findings, we hypothesize that the gradient in the thickness and curvature of the platelets may probably result from the difference in growth rate between the edge and the center of the shell and from the gradient in compressive stress imposed by the closing of the shells by the adductor muscles or the withdrawal of the periostracum by the mantle. We expect that the presented results will shed new light on the formation mechanisms of natural composite materials. - Highlights: • Flat and curved platelets coexist in green mussel shells. • The immature platelets at the shell edge consist of aragonite nanoparticles. • The immature platelets at the shell center are single crystals. • The morphology and thickness of platelets exhibit a gradient arrangement. • The gradient arrangement of platelets may result from the stress gradient.

The Organization of the Quorum Sensing luxI/R Family Genes in Burkholderia

Directory of Open Access Journals (Sweden)

Sándor Pongor

2013-07-01

Full Text Available Members of the Burkholderia genus of Proteobacteria are capable of living freely in the environment and can also colonize human, animal and plant hosts. Certain members are considered to be clinically important from both medical and veterinary perspectives and furthermore may be important modulators of the rhizosphere. Quorum sensing via N-acyl homoserine lactone signals (AHL QS is present in almost all Burkholderia species and is thought to play important roles in lifestyle changes such as colonization and niche invasion. Here we present a census of AHL QS genes retrieved from public databases and indicate that the local arrangement (topology of QS genes, their location within chromosomes and their gene neighborhoods show characteristic patterns that differ between the known Burkholderia clades. In sequence phylogenies, AHL QS genes seem to cluster according to the local gene topology rather than according to the species, which suggests that the basic topology types were present prior to the appearance of current Burkholderia species. The data are available at http://net.icgeb.org/burkholderia/.

The Organization of the Quorum Sensing luxI/R Family Genes in Burkholderia

Science.gov (United States)

Choudhary, Kumari Sonal; Hudaiberdiev, Sanjarbek; Gelencsér, Zsolt; Coutinho, Bruna Gonçalves; Venturi, Vittorio; Pongor, Sándor

2013-01-01

Members of the Burkholderia genus of Proteobacteria are capable of living freely in the environment and can also colonize human, animal and plant hosts. Certain members are considered to be clinically important from both medical and veterinary perspectives and furthermore may be important modulators of the rhizosphere. Quorum sensing via N-acyl homoserine lactone signals (AHL QS) is present in almost all Burkholderia species and is thought to play important roles in lifestyle changes such as colonization and niche invasion. Here we present a census of AHL QS genes retrieved from public databases and indicate that the local arrangement (topology) of QS genes, their location within chromosomes and their gene neighborhoods show characteristic patterns that differ between the known Burkholderia clades. In sequence phylogenies, AHL QS genes seem to cluster according to the local gene topology rather than according to the species, which suggests that the basic topology types were present prior to the appearance of current Burkholderia species. The data are available at http://net.icgeb.org/burkholderia/. PMID:23820583

Influence of Teaching Strategies and its Order of Exposure on Pre-Clinical Teeth Arrangement - A Pilot Study.

Science.gov (United States)

Jeyapalan, Karthigeyan; Mani, Uma Maheswari; Christian, Jayanth; Seenivasan, Madhan Kumar; Natarajan, Parthasarathy; Vaidhyanathan, Anand Kumar

2016-10-01

Teeth arrangement is a vital skill for the undergraduate dental student. The attainment of skills depends largely on the methodology of teaching. In a dental curriculum, the students are exposed to a wide variety of inputs and teaching methodologies from different sources. The educational unit in dental school must identify the sequence of teaching methods that enhance the learning and practising ability of students. The aim of this study was to evaluate the effectiveness of three different teaching methodologies for teeth arrangement and compare the differences between the orders of exposure to each teaching methodology on the development of teeth arrangement skills. The first year B.D.S students were study participants and were divided into three groups A, B, C. They were exposed to three teaching patterns namely live demonstration with video assisted teaching, group discussion with hand-outs and lectures with power point presentation. After each teaching methodology, their skill was assessed. The groups were exposed to three methodologies in different order for three arrangements. The scores obtained were analysed using Kruskal Wallis rank sum test and Dunn test for statistical significance. Significantly higher scores in the teeth arrangement procedure were obtained by the Group A students who were exposed initially to live demonstration with video-assisted teaching. Difference in the scores was noted among and within the groups. The difference between Group A and Group C was statistically significant after both first and third teeth arrangement (p=0.0031, p=0.0057). The study suggests each pre-clinical practice should begin with a live demonstration to enhance immediate learning absorption followed by lectures with power point presentation and group discussion for retention of knowledge and memory retrieval.

Somatotopic Arrangement and Location of the Corticospinal Tract in the Brainstem of the Human Brain

OpenAIRE

Jang, Sung Ho

2011-01-01

The corticospinal tract (CST) is the most important motor pathway in the human brain. Detailed knowledge of CST somatotopy is important in terms of rehabilitative management and invasive procedures for patients with brain injuries. In this study, I conducted a review of nine previous studies of the somatotopical location and arrangement at the brainstem in the human brain. The results of this review indicated that the hand and leg somatotopies of the CST are arranged medio-laterally in the mi...

Moessbauer Investigation of Spin Arrangements in Er2-xCexFe14B

International Nuclear Information System (INIS)

Bogacz, B.F.; Pedziwiatr, A.T.

2008-01-01

It was theoretically postulated earlier that in compounds Er 2-x Ce x Fe 14 B it may be possible to observe not only axial and planar spin arrangements but also a conical one. In order to experimentally verify this hypothesis, 57 Fe Moessbauer spectroscopy analysis was used to study the polycrystalline compounds Er 2-x Ce x Fe 14 B in the postulated composition region (x = 1.0, 1.1, 1.2, 1.3) in the wide range of temperatures. The obtained experimental data do not clearly support the suggestion of conical arrangement occurrence in the postulated compositions. They indicate that such phenomenon may be shifted towards higher Ce content. (authors)

Transfer arrangement for sealable enclosure

International Nuclear Information System (INIS)

Broxup, K.H.

1991-01-01

An arrangement for transferring items to or from e.g. a glovebox, in a closed moveable container. The glovebox port has a door having a non-rotatable outer portion and a rotatable inner portion. The container has a lid having a non-rotatable outer portion and a rotatable inner portion, the outer portion having a thin lip. The port has a thin lip which can be aligned with the lip of the lid. The outer portion of the door retains a peripheral sealing ring and the rim of the container retains a similar ring which can sandwich and bridge the two lips. The container is attached to the port by a rotatable locking ring. Via an externally rotatable and slidable shaft, lined at its inner end to the inner portion of the door, the latter is rotatable to disengage the door from the port, couple this inner portion to that of the lid, disengage the lid from the container, and move the coupled door and lid back and laterally away from the port, and vice versa. (author)

Completing the surrogate motherhood process: parental order reporters' attitudes towards surrogacy arrangements, role ambiguity and role conflict.

Science.gov (United States)

Purewal, Satvinder; Crawshaw, Marilyn; van den Akker, Olga

2012-06-01

This study investigated the attitudes of parental order reporters (PORs) towards their work with surrogacy arrangements and their experiences of role conflict and role ambiguity. A questionnaire was used to assess PORs' perceptions of their role in parental order [PO] applications, attitudes towards surrogacy arrangements and the legal process and the influence of role ambiguity or conflict. Questionnaires were distributed to all PORs employed by the Children and Family Court Advisory and Support Service in England. Thirty-three PORs participated (response rate 46%) who, on average, had each completed five PO applications (range 1-40). Positive attitudes towards surrogacy and the child's needs for openness about origins were found. Concerns about the inadequacy of preparation and assessment arrangements, overseas arrangements and non-regulation of surrogacy agencies were evident. PORs with high-role ambiguity were more likely to report less positive attitudes towards the emotional consequence of surrogacy on offspring. High scores on role ambiguity and role conflict were reflected in less positive attitudes towards the parties' preparation towards parenthood. These results have implications for training, policy and practice in this area.

Considerations on impact factors and institutional arrangements

International Nuclear Information System (INIS)

1979-04-01

The Delegation makes three comments on the work of the Group. First, the Group should consider the development of international safety standards governing occupational and environmental protection. Non-proliferation measures should not override these standards. Second, safeguards for reprocessing and plutonium recycle must be improved. The Japanese INFCE/DEP./WG-4/122 and French INFCE/DEP./WG-4/58 proposals are valuable contributions to this objective but the Group as a whole should make a broad assessment of safeguards. Lastly, the Delegation supports the development of new institutional arrangements for the fuel cycle which balance the rights and obligations of both suppliers and customers. In particular, the establishment of International Plutonium Storage is supported

High mass isotope separation process and arrangement

International Nuclear Information System (INIS)

Eerkens, J.W.

1978-01-01

An isotope separation arrangement for separating a preselected isotope from a mixture of chemically identical but isotopically different molecules by either photon-induced pure rovibrational or vibronic selective excitation of the molecules containing the atoms of the isotope to be separated from a lower to a higher energy state, and a chemical reaction of the higher energy state molecules with a chemically reactive agent to form a chemical compound containing primarily the atoms of isotope to be separated in a physicochemical state different from the physicochemical state of the mixture of chemically identical but isotopically different molecules. The chemical compound containing the atoms of the isotope to be separated may be subsequently processed to obtain the isotope

Calibration of an arbitrarily arranged projection moiré system for 3D shape measurement

Science.gov (United States)

Tang, Ying; Yao, Jun; Zhou, Yihao; Sun, Chen; Yang, Peng; Miao, Hong; Chen, Jubing

2018-05-01

An arbitrarily arranged projection moiré system is presented for three-dimensional shape measurement. We develop a model for projection moiré system and derive a universal formula expressing the relation between height and phase variation before and after we put the object on the reference plane. With so many system parameters involved, a system calibration technique is needed. In this work, we provide a robust and accurate calibration method for an arbitrarily arranged projection moiré system. The system no longer puts restrictions on the configuration of the optical setup. Real experiments have been conducted to verify the validity of this method.

Complex organisation and structure of the ghrelin antisense strand gene GHRLOS, a candidate non-coding RNA gene

Directory of Open Access Journals (Sweden)

Herington Adrian C

2008-10-01

frames. The gene is also non-conserved, with differential and tissue-restricted expression. The overlapping genomic arrangement of GHRLOS with the ghrelin gene indicates that it is likely to have interesting regulatory and functional roles in the ghrelin axis.

Novel insights into a retinoic-acid-induced cleft palate based on Rac1 regulation of the fibronectin arrangement.

Science.gov (United States)

Tang, Qinghuang; Li, Liwen; Lee, Min-Jung; Ge, Qing; Lee, Jong-Min; Jung, Han-Sung

2016-03-01

Retinoic acid (RA)-induced cleft palate results from both extrinsic obstructions by the tongue and internal factors within the palatal shelves. Our previous study showed that the spatiotemporal expression of Rac1 regulates the fibronectin (FN) arrangement through cell density alterations that play an important role in palate development. In this study, we investigate the involvement of the Rac1 regulation of the FN arrangement in RA-induced cleft palate. Our results demonstrate that RA-induced intrinsic alterations in palatal shelves, including a delayed progress of cell condensation, delay palate development, even after the removal of the tongue. Further analysis shows that RA treatment diminishes the region-distinctive expression of Rac1 within the palatal shelves, which reversely alters the fibrillar arrangement of FN. Furthermore, RA treatment disrupts the formation of lamellipodia, which are indicative structures of cell migration that are regulated by Rac1. These results suggest that the Rac1 regulation of the FN arrangement is involved in RA-induced cleft palate through the regulation of cell migration, which delays the progress of cell condensation and subsequently influences the FN arrangement, inducing a delay in palate development. Our study provides new insights into the RA-induced impairment of palatal shelf elevation based on cell migration dynamics.

Revised Arrangements for the Management of Solid and Non-Aqueous Radioactive Waste - 12452

Energy Technology Data Exchange (ETDEWEB)

Fullbrook, Michael; Walker, Johann; Macnab, Alec [Atomic Weapons Establishment, Aldermaston (United Kingdom)

2012-07-01

In 2010, Atomic Weapons Establishment (AWE) identified a requirement to implement revised management arrangements for the generation, storage and disposal of radioactive waste. A thorough review of the current arrangements/processes was undertaken which included both legal compliance requirements and the identification of business improvement opportunities. On completion of this review a suitable project team was established and in 2011 an integrated Radioactive Waste Management process was implemented throughout the business. Initial results have shown measurable improvements within Radioactive Waste management compliance, operator understanding and increased business efficiency. Through the development and implementation of the revised working arrangements AWE has been able to continue to demonstrate both legal compliance to its regulators along with business efficiency and effectiveness improvements. Simple to follow process maps have improved employees understanding of Radioactive Waste management requirements, provided them with easily accessible information and ensured the business operates in a single coherent manner. The implementation of a modern electronic data management system has ensured all waste related information is easily retrievable and appropriately maintained. The additional functions that have been built into the system have reduced the potential for human error and increased the overall efficiency of the Waste Management department through the use of the automated report generation functionality. (authors)

The Development of Computer-Aided Design for Electrical Equipment Selection and Arrangement of 10 Kv Switchgear

Directory of Open Access Journals (Sweden)

Chernaya Anastassiya

2015-01-01

Full Text Available The paper intends to give an overview of a computer-aided design program application. The research includes two main parts: the development of a computer-aided design for an appropriate switchgear selection and its arrangement in an indoor switchgear layout. Matlab program was used to develop a computer-aided design system. The use of this program considerably simplifies the selection and arrangement of 10 kV switchgear.

Allocation of public and-or private responsibilities. Governance arrangements for green roofs

NARCIS (Netherlands)

Mees, H.L.P.

2012-01-01

This research was commissioned by Knowledge for Climate, Hotspot Rotterdam Region (http://knowledgeforclimate.climateresearchnetherlands.nl/hotspots/rotterdam-region), and included an international comparison of governance arrangements for the promotion of green roofs as an innovative no-regrets

What about the grandparents? Children's postdivorce residence arrangements and contact with grandparents

NARCIS (Netherlands)

Westphal, Sarah Katharina; Poortman, Anne Rigt; Van der Lippe, Tanja

2015-01-01

Despite the importance of grandparents in their grandchildren's lives, little is known about grandparent-grandchild contact after parental divorce. In this study, the authors investigated differences in grandparent-grandchild contact across 3 postdivorce residence arrangements (mother residence,

46 CFR 133.160 - Rescue boat embarkation, launching and recovery arrangements.

Science.gov (United States)

2010-10-01

...) OFFSHORE SUPPLY VESSELS LIFESAVING SYSTEMS Requirements for All OSVs § 133.160 Rescue boat embarkation, launching and recovery arrangements. (a) Each davit for a rescue boat must be approved under approval series... 46 Shipping 4 2010-10-01 2010-10-01 false Rescue boat embarkation, launching and recovery...

Plus C'est La Même Chose: Joinery Apprenticeship Arrangements in Scotland

Science.gov (United States)

Anderson, Pauline

2014-01-01

This paper examines recent changes in the Scottish apprenticeship system of skill formation for joiners through an occupational skill ecosystem lens. Building trade apprenticeships in Scotland are based around a social partnership model more akin to "dual systems" than typical arrangements elsewhere in the UK. Drawing on in-depth…

Mitochondrial Genomes of Kinorhyncha: trnM Duplication and New Gene Orders within Animals

OpenAIRE

Popova, Olga V.; Mikhailov, Kirill V.; Nikitin, Mikhail A.; Logacheva, Maria D.; Penin, Aleksey A.; Muntyan, Maria S.; Kedrova, Olga S.; Petrov, Nikolai B.; Panchin, Yuri V.; Aleoshin, Vladimir V.

2016-01-01

Many features of mitochondrial genomes of animals, such as patterns of gene arrangement, nucleotide content and substitution rate variation are extensively used in evolutionary and phylogenetic studies. Nearly 6,000 mitochondrial genomes of animals have already been sequenced, covering the majority of animal phyla. One of the groups that escaped mitogenome sequencing is phylum Kinorhyncha-an isolated taxon of microscopic worm-like ecdysozoans. The kinorhynchs are thought to be one of the earl...

The role of ABC genes in shaping perianth phenotype in the basal angiosperm Magnolia.

Science.gov (United States)

Wróblewska, M; Dołzbłasz, A; Zagórska-Marek, B

2016-03-01

It is generally accepted that the genus Magnolia is characterised by an undifferentiated perianth, typically organised into three whorls of nearly identical tepals. In some species, however, we encountered interesting and significant perianth modifications. In Magnolia acuminata, M. liliiflora and M. stellata the perianth elements of the first whorl are visually different from the others. In M. stellata the additional, spirally arranged perianth elements are present above the first three whorls, which suggests that they have been formed within the domain of stamen primordia. In these three species, we analysed expression patterns of the key flower genes (AP1, AGL6, AP3, PI, AG) responsible for the identity of flower elements and correlated them with results of morphological and anatomical investigations. In all studied species the elements of the first whorl lacked the identity of petals (lack of AP3 and PI expression) but also that of leaves (presence of AGL6 expression), and this seems to prove their sepal character. The analysis of additional perianth elements of M. stellata, spirally arranged on the elongated floral axis, revealed overlapping and reduced activity of genes involved in specification of the identity of the perianth (AGL6) but also of generative parts (AG), even though no clear gradient of morphological changes could be observed. In conclusion, Magnolia genus is capable of forming, in some species, a perianth differentiated into a calyx (sepals) and corolla (petals). Spirally arranged, additional perianth elements of M. stellata, despite activity of AG falling basipetally, resemble petals. © 2015 German Botanical Society and The Royal Botanical Society of the Netherlands.

Post-divorce custody arrangements and binuclear family structures of Flemish adolescents

Directory of Open Access Journals (Sweden)

An Katrien Sodermans

2013-03-01

Full Text Available BACKGROUND Because of the tendency towards equal parental rights in post-divorce custody decisions, the number of children living partially in two households after divorce has increased. Because of this evolution, traditional family typologies have been challenged. OBJECTIVE In this study, we want to describe the post-divorce custody arrangements and family configurations of Flemish adolescents (between 12 and 18 years old. METHODS We use four waves of the Leuven Adolescents and Families Study, a yearly survey in which adolescents are questioned at school about their family life, family relationships and various dimensions of their wellbeing. Our research sample consists of 1525 adolescents who experienced a parental break-up. First, we present information on the proportion of adolescents in different custody arrangements, according to divorce cohort, age and sex. Next, we describe post-divorce family configurations, according to the custody arrangement and different criteria of co-residence between children and step-parents. RESULTS We observe a higher proportion of adolescents spending at least 33Š of time in both parental households (shared residence for more recent divorce cohorts. A large proportion of adolescents is living with a new partner of the mother or father, but there are important differences, according to the criteria used to define stepfamily configurations. CONCLUSIONS The relatively high incidence figures of children in shared residence challenge the current dichotomous post-divorce family concept in terms of single parent families and stepfamilies. Family typologies applying a binuclear perspective are therefore increasingly meaningful and necessary. In addition, shared residence increases the chance of co-residence with at least one step-parent, and increases the proportion of children with a part-time residential stepmother.

Conditions for the Evolution of Gene Clusters in Bacterial Genomes

Science.gov (United States)

Ballouz, Sara; Francis, Andrew R.; Lan, Ruiting; Tanaka, Mark M.

2010-01-01

Genes encoding proteins in a common pathway are often found near each other along bacterial chromosomes. Several explanations have been proposed to account for the evolution of these structures. For instance, natural selection may directly favour gene clusters through a variety of mechanisms, such as increased efficiency of coregulation. An alternative and controversial hypothesis is the selfish operon model, which asserts that clustered arrangements of genes are more easily transferred to other species, thus improving the prospects for survival of the cluster. According to another hypothesis (the persistence model), genes that are in close proximity are less likely to be disrupted by deletions. Here we develop computational models to study the conditions under which gene clusters can evolve and persist. First, we examine the selfish operon model by re-implementing the simulation and running it under a wide range of conditions. Second, we introduce and study a Moran process in which there is natural selection for gene clustering and rearrangement occurs by genome inversion events. Finally, we develop and study a model that includes selection and inversion, which tracks the occurrence and fixation of rearrangements. Surprisingly, gene clusters fail to evolve under a wide range of conditions. Factors that promote the evolution of gene clusters include a low number of genes in the pathway, a high population size, and in the case of the selfish operon model, a high horizontal transfer rate. The computational analysis here has shown that the evolution of gene clusters can occur under both direct and indirect selection as long as certain conditions hold. Under these conditions the selfish operon model is still viable as an explanation for the evolution of gene clusters. PMID:20168992

IFMIF - Layout and arrangement of cells according to requirements of technical logistics, reliability and remote handling

Energy Technology Data Exchange (ETDEWEB)

Mittwollen, Martin, E-mail: martin.mittwollen@kit.edu [Karlsruhe Institute of Technology, Institute for Conveying Technology and Logistics, Karlsruhe (Germany); Eilert, Dirk; Kubaschewski, Martin; Madzharov, Vladimir [Karlsruhe Institute of Technology, Institute for Conveying Technology and Logistics, Karlsruhe (Germany); Tian Kuo [Karlsruhe Institute of Technology, Institute for Neutron Physics and Reactor Technology, Karlsruhe (Germany)

2012-08-15

Highlights: Black-Right-Pointing-Pointer In a first approach, layout and arrangement of the cells followed a predetermined plant layout. Black-Right-Pointing-Pointer Disadvantages in technical logistics, reliability and remote handling have been detected. Black-Right-Pointing-Pointer Deliberation with project teams opened space for improvements. Black-Right-Pointing-Pointer Layout and arrangement of cells have been improved by simplification of design. Black-Right-Pointing-Pointer Speed and reliability have been increased significantly. - Abstract: The International Fusion Material Irradiation Facility (IFMIF) is designed to study and qualify structural and functional materials which shall be used in future fusion nuclear power plants. During the current engineering validation and engineering design activities (EVEDA) phase the development of e.g. an optimized layout and arrangement of the cells (Access Cell, Test Cell, and Test Module Handling Cells) is of major interest. After defining different functions for the individual cells like e.g. large scale/fine scale disassembling of test modules a first layout has been developed. This design followed requirements like having a minimum of carrier changes to avoid sources of failures. On the other hand it has had to be a compact arrangement of cells due to restrictions from plant layout. A row of changes of transfer direction, and different crane systems were the consequence. Constructive discussion with project team results in the statement, that for reasons of being reliable and fast, layout and arrangement of cells goes first, plant layout then will follow. The chance for big improvements was taken and the result was a simplified design with strong reduced number of functional elements, and increased reliability and speed.

Obesity and lifestyle in U.S. college students related to living arrangements.

Science.gov (United States)

Brunt, Ardith R; Rhee, Yeong S

2008-11-01

The purpose of this paper is to determine if living arrangements influence dietary variety and other health behaviors among American college students. A generalized linear model was used to assess differences between students in various living arrangements. Results showed that off-campus students were more likely to be overweight/obese, consume more alcohol, and smoke than those who lived on-campus or with parents. Compared to students who lived off-campus, those who lived on-campus consumed a larger variety of fruits, vegetables, and dairy products. Those who lived off-campus consumed less variety of grains compared to those who lived with parents. There were no significant differences in variety of meat, meat alternatives, or snacks between the three groups. To prevent future chronic diseases, health educators should target off-campus students to improve dietary and lifestyle behaviors.

Flexible work arrangements, job satisfaction, and turnover intentions: the mediating role of work-to-family enrichment.

Science.gov (United States)

McNall, Laurel A; Masuda, Aline D; Nicklin, Jessica M

2010-01-01

The authors examined the relation between the availability of 2 popular types of flexible work arrangements (i.e., flextime and compressed workweek) and work-to-family enrichment and, in turn, the relation between work-to-family enrichment and (a) job satisfaction and (b) turnover intentions. In a sample of 220 employed working adults, hierarchical regression analyses showed that work-to-family enrichment mediated the relation between flexible work arrangements and both job satisfaction and turnover intentions, even after controlling for gender, age, marital status, education, number of children, and hours worked. Thus, the availability of flexible work arrangements such as flextime and compressed workweek seems to help employees experience greater enrichment from work to home, which, in turn, is associated with higher job satisfaction and lower turnover intentions. The authors discuss the implications for research and practice.