Influence of organic nitro-compounds and of surface active compounds on the inverse voltametric determination of cadmium, lead and copper

Energy Technology Data Exchange (ETDEWEB)

Wahdat, F; Neeb, R

1983-12-01

The influence of surface active agents and of organic nitro-compounds alone and in combination on the potentiometric stripping analysis and anodic-stripping differential-pulse-polarography of Cd, Pb and Cu is investigated. In some cases PSA offers advantages for the determination of these elements in the presence of organic nitro-compounds in comparison with differential pulse-polarography.

Determination of complex formation constants by phase sensitive alternating current polarography: Cadmium-polymethacrylic acid and cadmium-polygalacturonic acid.

Science.gov (United States)

Garrigosa, Anna Maria; Gusmão, Rui; Ariño, Cristina; Díaz-Cruz, José Manuel; Esteban, Miquel

2007-10-15

The use of phase sensitive alternating current polarography (ACP) for the evaluation of complex formation constants of systems where electrodic adsorption is present has been proposed. The applicability of the technique implies the previous selection of the phase angle where contribution of capacitive current is minimized. This is made using Multivariate Curve Resolution by Alternating Least Squares (MCR-ALS) in the analysis of ACP measurements at different phase angles. The method is checked by the study of the complexation of Cd by polymethacrylic (PMA) and polygalacturonic (PGA) acids, and the optimal phase angles have been ca. -10 degrees for Cd-PMA and ca. -15 degrees for Cd-PGA systems. The goodness of phase sensitive ACP has been demonstrated comparing the determined complex formation constants with those obtained by reverse pulse polarography, a technique that minimizes the electrode adsorption effects on the measured currents.

Voltammetric Behaviour and Analysis of Fluchloralin

OpenAIRE

K. Balaji; C. Sridevi; N. Ananda Kumar Reddy; K. Mohana Muni Sidda Reddy; C. Suresh Reddy

2010-01-01

The electrochemical reduction behavior of fluchloralin has been studied by D.C.polarography, differential pulse polarography, millicoulometry and controlled potential electrolysis in the universal buffers ranging from 2.0 to 12.0. Kinetic parameters were evaluated and a reduction mechanism was proposed. A simple and rapid differential pulse polarographic method has been developed for the determination of fluchloralin in formulations, grains, soils and spiked water samples. The lower detection...

Conformational changes in DNA caused by DNA-ase I, gamma and ultraviolet radiation as revealed by differential pulse polarography

International Nuclear Information System (INIS)

Vorlickova, M.

1979-01-01

The height, potential and half width of differential pulse-polarographic peaks of DNA were investigated in dependence on degradation by DNA-ase I and gamma and UV radiation. It was found that in all cases studied growth of peak II (reflecting conformational changes in the DNA double helix) was limited, and only after it reached a certain height further degradation induced the appearance of peak III of single-stranded DNA. This course is explained as reflecting the limited extent of conformational changes in the framework of the double helix, which probably follows from a limited number of sites that can undergo certain types of conformational changes. The character of the conformational changes is dependent on the chemical nature of the damage. (author)

Uranium determination in phosphatized materials by drop electrode polarography

International Nuclear Information System (INIS)

Sequeira, F.M.C. de; Abrao, A.

1987-01-01

An uranium determination procedure in phosphate rocks and crude phosphoric acid is outlined polarography is used. Uranium is previously separedted by extraction with tri-n-byte phosphate 10%-petroleum ether using aluminium nitrate as salting out agent. (M.L.J.) [pt

Modern applications of polarography and voltammetry to inorganic analysis

International Nuclear Information System (INIS)

Lee, A.F.

1983-01-01

This report summarized developments in polarography and voltametry up to 1982. Modern electronic equipment and scanning waveforms are explained briefly. Extensive tables of recent inorganic applications, mainly in the geochemical and metallurgical fields, are included, and show results based on the new approaches

Voltammetric Behaviour and Analysis of Fluchloralin

Directory of Open Access Journals (Sweden)

K. Balaji

2010-01-01

Full Text Available The electrochemical reduction behavior of fluchloralin has been studied by D.C.polarography, differential pulse polarography, millicoulometry and controlled potential electrolysis in the universal buffers ranging from 2.0 to 12.0. Kinetic parameters were evaluated and a reduction mechanism was proposed. A simple and rapid differential pulse polarographic method has been developed for the determination of fluchloralin in formulations, grains, soils and spiked water samples. The lower detection limit was found to be 1.5×10-8 M. Both the standard addition and calibration methods were used for the analytical measurements.

Electrochemical behaviour of some neuroleptics: Haloperidol and its derivatives.

Science.gov (United States)

Vire, J C; Fischer, M; Patriarche, G J; Christian, G D

1981-05-01

The electrochemical characteristics of Haloperidol and related compounds, representative neuroleptics of the butyrophenone family, have been investigated as a function of pH and concentration by direct-current, alternating-current and differential-pulse polarography and cyclic voltammetry at a hanging mercury drop electrode. A single cathodic wave representing an irreversible two-electron reduction is obtained, and its half-wave potential differs from that characteristic of aromatic ketone reduction. Adsorption processes disturb the wave behaviour and an adsorption prewave is observed at high concentrations. Quantitative measurements were successful in the concentration range 1 x 10(-4)-1 x 10(-6)M (0.4 mg/l.), the lower concentration representing the detection limit by differential-pulse polarography.

Differential pulse polarographic determination of trace antimony in standard biological samples after preconcentration using 2-nitroso-1-naphthol-4-sulfonic acid

International Nuclear Information System (INIS)

Taher, M. A.

2003-01-01

A highly selective, rapid and economical differential polarographic method has been developed for the determination of trace amounts of antimony in various standard alloys and biological samples after of its 2-naphthol-4 sulfonic acid tetradecyl dimethylbenzylammonium chloride on microcrystalline naphthalene in the ph range of 7.5-11.0. After filtration, the solid mass is shaken with 8-10 ml of 1 M hydrochloric acid (with preconcentration factor of 10) and antimony is determined by differential pulse polarography. Antimony can alternatively be quantitatively absorbed on 2-nitroso-1-naphthol-4-sulfonic acid tetradecyl dimethylbenzylammonium-naphthalene absorbed packed in a column (with preconcentration factor of 30) and determined similarly. In this case, 1.5 μg of antimony can be concentrated in a column from 300 ml of aqueous sample, where its concentration is as low as 5 ng/ml. Characterization of the electro active process included an examination of the degree of reversibility. The results show that the irreversibility of antimony. Various parameters such as the effect of ph, volume of aqueous phase, HCl concentration, reagent concentration, naphthalene concentration, shaking time and interference of a number of metal ions on the determination of antimony have been studied in detail to optimize the conditions for determination in standard alloys and standard biological samples

Pulsed feedback defers cellular differentiation.

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Joe H Levine

2012-01-01

Full Text Available Environmental signals induce diverse cellular differentiation programs. In certain systems, cells defer differentiation for extended time periods after the signal appears, proliferating through multiple rounds of cell division before committing to a new fate. How can cells set a deferral time much longer than the cell cycle? Here we study Bacillus subtilis cells that respond to sudden nutrient limitation with multiple rounds of growth and division before differentiating into spores. A well-characterized genetic circuit controls the concentration and phosphorylation of the master regulator Spo0A, which rises to a critical concentration to initiate sporulation. However, it remains unclear how this circuit enables cells to defer sporulation for multiple cell cycles. Using quantitative time-lapse fluorescence microscopy of Spo0A dynamics in individual cells, we observed pulses of Spo0A phosphorylation at a characteristic cell cycle phase. Pulse amplitudes grew systematically and cell-autonomously over multiple cell cycles leading up to sporulation. This pulse growth required a key positive feedback loop involving the sporulation kinases, without which the deferral of sporulation became ultrasensitive to kinase expression. Thus, deferral is controlled by a pulsed positive feedback loop in which kinase expression is activated by pulses of Spo0A phosphorylation. This pulsed positive feedback architecture provides a more robust mechanism for setting deferral times than constitutive kinase expression. Finally, using mathematical modeling, we show how pulsing and time delays together enable "polyphasic" positive feedback, in which different parts of a feedback loop are active at different times. Polyphasic feedback can enable more accurate tuning of long deferral times. Together, these results suggest that Bacillus subtilis uses a pulsed positive feedback loop to implement a "timer" that operates over timescales much longer than a cell cycle.

Fast differential pulse discriminator-counter

International Nuclear Information System (INIS)

Shelevoj, K.D.

1985-01-01

The flowsheet of a differential pulse discriminator counter is described; the result of discrimination here is independent from the shape of the input pulse. Rate of the analysis of input pulses with minimum amplitude up to 0.3 mV coming out from the photomultiplier makes up 220 MHz. The flowsheet of the discriminator used in the system of photon counting for atmosphere probing is presented

Preconcentration of trace uranium from seawater with solid phase extraction followed by differential pulse polarographic determination in chloroform eluate

International Nuclear Information System (INIS)

Dojozan, Dj.; Pournaghi-Azar, M.H.; Toutounchi-Asr, J.

1998-01-01

In the present study, an effective method is presented for the separation and preconcentration of uranium (VI) by solid phase extraction (SPE). For this purpose, U(VI) oxinate is formed by the reaction of U(VI) with 8-hydroxyquinoline and adsorbed onto the octylsilane (C-8) SPE cartridge. The analyte is completely eluted with chloroform and determined by differential pulse polarography. The SPE conditions were optimized by evaluating the effective factors such as pH, oxine concentration, type and concentration of buffer and masking agent. By the proposed method a preconcentration factor of more than 100 was achieved. The average recovery of uranium (VI) oxinate (0.1 mg l -1 ) was 99.8%. The relative standard deviation was 1.6% for seven replicate determinations of uranyl ion in the solution with a concentration 20 μg l -1 . Some concomitant ions such as Ca +2 , Mg +2 and Fe +3 which interfere in extraction or determination process of uranium were masked with EDTA in aqueous phase during the extraction process. The proposed method was successfully used for the determination of uranium in Caspian Sea and Persian Gulf water samples

Abstracts of the 3. Brazilian Meeting on Analytical Chemistry

International Nuclear Information System (INIS)

1985-01-01

Abstracts from experimental research works on analytical chemistry are presented. The following techniques were mainly used: differential pulse polarography, atomic absorption spectrophotometry, ion exchange chromatography and gamma spectroscopy. (C.L.B.) [pt

Analysis of molybdenum, chromium, vanadium and iron by polarographic techniques

International Nuclear Information System (INIS)

Al-Zand, T.K.

1986-01-01

The application of direct current Tast polarograph, differential pulse polarography and phase-selective alternative current Tast polarography to the problem of determining molybdenum, chromium, vanadium and iron in various supporting electrolytes is reported. The effect of the supporting electrolyte on the wave/peak potential and sensitivity of the metal ion have been examined. The polarographic methods were applied for simultaneous determination of chromium (3)/chromium (6), vanadium (4), vanadium (5) and iron (2)/iron (3) in different supporting electrolytes

CAMAC differential pulse discriminator-counter

International Nuclear Information System (INIS)

Tselikov, N.V.

1987-01-01

Differential pulse discriminator-counter for Moessbauer spectrometer is described. Input pulse setting into the channel is performed according to the following algorithm: the pulse is transmitted to the channel depending on the fact whether the preceding pulse has got to the discrimination window or not. The circuit does not contain delay lines, taking into account the delay of a signal from the upper level discriminator in relation to the lower level discriminator signal, which is connected with input pulse rise finite time, which in turn allows one to reduce the discriminator dead time up to the operation time of threshold circuits. The pulse counting rate is 150 MHz, input signal amplitude is ±3 V, dead time is 6 ns, delay time from input to output is 14 ns. The unit is made in CAMAC system

75 years of J. Heyrovsky's Oscillographic Polarography and Present Constant Current Chronopotentiometry

Czech Academy of Sciences Publication Activity Database

Paleček, Emil; Heyrovský, Michael

2017-01-01

Roč. 111, č. 1 (2017), s. 73-77 ISSN 0009-2770 Institutional support: RVO:68081707 ; RVO:61388955 Keywords : oscillographic polarography with controlled current * constant current chronopotentiometry * electrochemistry of nucleic acids Subject RIV: CG - Electrochemistry; CG - Electrochemistry (UFCH-W) OBOR OECD: Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis); Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis) (UFCH-W) Impact factor: 0.387, year: 2016

CAMAC-compatible differential pulse discriminator-counter

International Nuclear Information System (INIS)

Tselikov, I.V.

1988-01-01

A differential pulse discriminator-counter for a Moessbauer spectrometer is described. Input pulses are collected according to the following algorithm; a pulse is admitted into the channel depending on whether or not the preceding pulse fell into the discrimination window. The circuit does not contain delay lines to allow for the delay lines to allow for the delay of the signal from the upper-level discriminator with respect to the signal from the lower-level discriminator due to the finite rise time of the input pulses, which makes it possible to reduce the dead time of the discriminator to the actuation time of the threshold circuits. The pulse count rate is 150 MHz, the input amplitude is +/-3 V, the dead time is 6 nsec, and the delay from input to output is 14 nsec. The unit is CAMAC-compatible

Pulsed DC Electric Field-Induced Differentiation of Cortical Neural Precursor Cells.

Directory of Open Access Journals (Sweden)

Hui-Fang Chang

Full Text Available We report the differentiation of neural stem and progenitor cells solely induced by direct current (DC pulses stimulation. Neural stem and progenitor cells in the adult mammalian brain are promising candidates for the development of therapeutic neuroregeneration strategies. The differentiation of neural stem and progenitor cells depends on various in vivo environmental factors, such as nerve growth factor and endogenous EF. In this study, we demonstrated that the morphologic and phenotypic changes of mouse neural stem and progenitor cells (mNPCs could be induced solely by exposure to square-wave DC pulses (magnitude 300 mV/mm at frequency of 100-Hz. The DC pulse stimulation was conducted for 48 h, and the morphologic changes of mNPCs were monitored continuously. The length of primary processes and the amount of branching significantly increased after stimulation by DC pulses for 48 h. After DC pulse treatment, the mNPCs differentiated into neurons, astrocytes, and oligodendrocytes simultaneously in stem cell maintenance medium. Our results suggest that simple DC pulse treatment could control the fate of NPCs. With further studies, DC pulses may be applied to manipulate NPC differentiation and may be used for the development of therapeutic strategies that employ NPCs to treat nervous system disorders.

Pulsed DC Electric Field-Induced Differentiation of Cortical Neural Precursor Cells.

Science.gov (United States)

Chang, Hui-Fang; Lee, Ying-Shan; Tang, Tang K; Cheng, Ji-Yen

2016-01-01

We report the differentiation of neural stem and progenitor cells solely induced by direct current (DC) pulses stimulation. Neural stem and progenitor cells in the adult mammalian brain are promising candidates for the development of therapeutic neuroregeneration strategies. The differentiation of neural stem and progenitor cells depends on various in vivo environmental factors, such as nerve growth factor and endogenous EF. In this study, we demonstrated that the morphologic and phenotypic changes of mouse neural stem and progenitor cells (mNPCs) could be induced solely by exposure to square-wave DC pulses (magnitude 300 mV/mm at frequency of 100-Hz). The DC pulse stimulation was conducted for 48 h, and the morphologic changes of mNPCs were monitored continuously. The length of primary processes and the amount of branching significantly increased after stimulation by DC pulses for 48 h. After DC pulse treatment, the mNPCs differentiated into neurons, astrocytes, and oligodendrocytes simultaneously in stem cell maintenance medium. Our results suggest that simple DC pulse treatment could control the fate of NPCs. With further studies, DC pulses may be applied to manipulate NPC differentiation and may be used for the development of therapeutic strategies that employ NPCs to treat nervous system disorders.

Electrochemical methods for monitoring of environmental carcinogens.

Science.gov (United States)

Barek, J; Cvacka, J; Muck, A; Quaiserová, V; Zima, J

2001-04-01

The use of modern electroanalytical techniques, namely differential pulse polarography, differential pulse voltammetry on hanging mercury drop electrode or carbon paste electrode, adsorptive stripping voltammetry and high performance liquid chromatography with electrochemical detection for the determination of trace amounts of carcinogenic N-nitroso compounds, azo compounds, heterocyclic compounds, nitrated polycyclic aromatic hydrocarbons and aromatic and heterocyclic amines is discussed. Scope and limitations of these methods are described and some practical applications based on their combination with liquid-liquid or solid phase extraction are given.

Studies on the electrochemical behavior of heavy lanthanide ions and the synthesis, characterization of heavy metal chelate complexes

International Nuclear Information System (INIS)

Kang, Sam Woo; Chang, Choo Hwan; Son, Byung Chan; Suh, Moo Yul; Kim, Chae Kyun

1991-01-01

Electrochemical behavior of some heavy lanthanide ions(Gd 3+ , Tb 3+ , Dy 3+ , Ho 3+ , Er 3+ , Tm 3+ , Yb 3+ and Lu 3+ ) in various supporting electrolytes has been investigated by dc polarography, differential pulse polarography and cyclic voltammetry. The peak potentials and the peak currents, their dependency on the concentration and pH effects, the reversibility of the electrode reactions are described. The reduction of Gd 3+ , Tb 3+ , Dy 3+ , Ho 3+ , Er 3+ , Tm 3+ and Lu 3+ ions in 0.1M lithium chloride solution proceeds by a three-electron change directly to the metallic state, whereas the reduction of Yb 3+ proceeds by a one-electron change followed by a two-electron change. It was found that, in differential pulse polarography and cyclic voltammetry, the peak potential, peak current and current function showed constant value in the pH range of 4.0-6.0 by varying pH and scan rates. And also the current function is found to decrease as the sweep rate is increased when the pH reaches 4.0. This fact may indicate a chemical reaction coupled with the electrochemical reaction at lower pH values(pH 3+ ion is possible to determine voltammetrically within the error of ±3.5% in the presence of other competitive lanthanide ions. (Author)

Electrochemical Studies of the Inhibition and Activation Effects of Al (III on the Activity of Bovine Liver Glutamate Dehydrogenase

Directory of Open Access Journals (Sweden)

Shuping Bi

2005-04-01

Full Text Available Since the study of Al3+ ion on the enzyme activity by using of electrochemical techniques was rarely found in available literatures, the differential-pulse polarography (DPP technique was applied to study the effects of Al3+ ion on the glutamate dehydrogenase (GDH activity in the catalytical reaction of α-KG +NADH+NH4 + ⇔ L-Glu+NAD++H2O by monitoring the DPP reduction current of NAD+. At the plant and animal physiologically relevant pH values (pH=6.5 and 7.5, the GDH enzyme activities were strongly depended on the concentrations of the metal ion in the assay mixture solutions. In the lower Al (III concentration solutions (80μM, the inhibition effects of Al (III were shown again. The cyclic voltammetry of NAD+ and NAD+-GDH in the presence of Al (III can help to explain some biological phenomena. According to the differential-pulse polarography and cyclic voltammetry experiments, the present research confirmed that the electrochemical technique is a convenient and reliable sensor for accurate determination of enzyme activity in biological and environmental samples.

Comparison Study of Voltammetric Behavior of Muscle Relaxant Dantrolene Sodium on Silver Solid Amalgam and Bismuth Film Electrodes

Czech Academy of Sciences Publication Activity Database

Šelešovská, R.; Martinková, P.; Štěpánková, M.; Navrátil, Tomáš; Chýlková, J.

2017-01-01

Roč. 2017, č. 2017 (2017), č. článku 3627428. ISSN 2090-8865 R&D Projects: GA ČR GA17-03868S Institutional support: RVO:61388955 Keywords : performance liquid-chromatography * differential-pulse polarography * anodic-stripping voltammetry * screen-printed electrodes * organic-compounds Subject RIV: CG - Electrochemistry OBOR OECD: Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis) Impact factor: 1.801, year: 2016

Comparison Study of Voltammetric Behavior of Muscle Relaxant Dantrolene Sodium on Silver Solid Amalgam and Bismuth Film Electrodes

Czech Academy of Sciences Publication Activity Database

Šelešovská, R.; Martinková, P.; Štěpánková, M.; Navrátil, Tomáš; Chýlková, J.

2017-01-01

Roč. 2017, č. 2017 (2017), č. článku 3627428. ISSN 2090-8865 R&D Projects: GA ČR GA17-03868S Institutional support: RVO:61388955 Keywords : performance liquid - chromatography * differential-pulse polarography * anodic-stripping voltammetry * screen-printed electrodes * organic-compounds Subject RIV: CG - Electrochemistry OBOR OECD: Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis) Impact factor: 1.801, year: 2016

Pulse retrieval algorithm for interferometric frequency-resolved optical gating based on differential evolution.

Science.gov (United States)

Hyyti, Janne; Escoto, Esmerando; Steinmeyer, Günter

2017-10-01

A novel algorithm for the ultrashort laser pulse characterization method of interferometric frequency-resolved optical gating (iFROG) is presented. Based on a genetic method, namely, differential evolution, the algorithm can exploit all available information of an iFROG measurement to retrieve the complex electric field of a pulse. The retrieval is subjected to a series of numerical tests to prove the robustness of the algorithm against experimental artifacts and noise. These tests show that the integrated error-correction mechanisms of the iFROG method can be successfully used to remove the effect from timing errors and spectrally varying efficiency in the detection. Moreover, the accuracy and noise resilience of the new algorithm are shown to outperform retrieval based on the generalized projections algorithm, which is widely used as the standard method in FROG retrieval. The differential evolution algorithm is further validated with experimental data, measured with unamplified three-cycle pulses from a mode-locked Ti:sapphire laser. Additionally introducing group delay dispersion in the beam path, the retrieval results show excellent agreement with independent measurements with a commercial pulse measurement device based on spectral phase interferometry for direct electric-field retrieval. Further experimental tests with strongly attenuated pulses indicate resilience of differential-evolution-based retrieval against massive measurement noise.

A study of the photocatalytic effects of aqueous suspensions of platinized semiconductor materials on the reaction rates of candidate redox reactions

Science.gov (United States)

Miles, A. M.

1982-01-01

The effectiveness of powdered semiconductor materials in photocatalyzing candidate redox reactions was investigated. The rate of the photocatalyzed oxidation of cyanide at platinized TiO2 was studied. The extent of the cyanide reaction was followed directly using an electroanalytical method (i.e. differential pulse polarography). Experiments were performed in natural or artificial light. A comparison was made of kinetic data obtained for photocatalysis at platinized powders with rate data for nonplatinized powders.

Voltammetric Behaviour of Metronidazole at Mercury Electrodes

Directory of Open Access Journals (Sweden)

La-Scalea Mauro A.

1999-01-01

Full Text Available Metronidazole is the most important drug of the group of 5-nitroimidazoles and possesses toxicity to anaerobic micro-organisms DNA being the main target for their biological action. The mechanism of biological action of metronidazole is dependent upon the nitro group reduction process. The reduction of metronidazole is pH dependent in acid medium and four electrons are involved in the complete reduction to the hydroxylamine derivative. In aprotic medium the reduction of the metronidazole occurs in two steps, the first involving one electron to form the nitro radical and the second step involving three more electrons until the formation of the hydroxylamine derivative. In this paper the mechanism of reduction of metronidazole was studied by using the voltammetric techniques: d.c. polarography, differential pulse polarography and cyclic voltammetry using the mercury drop as the working electrode.

Polarographic behaviour and determination of uranium(VI) in alcoholic solutions from organic extraction phases

International Nuclear Information System (INIS)

Degueldre, C.; Taibi, K.

1996-01-01

The determination of U(VI) in organic extraction phases: hydrocarbon-diethyl-2-hexyl phosphoric acid-trioctylphosphine oxide and hydrocarbon-tri-n-octylamine, diluted by an alcohol has been studied by direct current polarography, as well as by differential pulse polarography (DPP). In order to optimise the analytical procedure, miscibility and conductivity studies of the mixtures hydrocarbon-alcohol (ethanol, n- and isopropanol and n- and isobutanol) were made after addition of sulphuric acid as a supporting electrolyte. In the solutions of sulphuric acid in the alcohol-extractant-hydrocarbon phases, U(VI) gives rise to well defined polarograms. Its electroreduction involves a single electron step in all cases. The DPP peak height is proportional to the U(VI) concentration between 2x10 -6 and 2x10 -3 M, and the 3σ detection limit is ca. 10 -6 M

Differential Pulse Anodic Stripping Voltammetry for Mercury Determination

OpenAIRE

Vereștiuc Paul C.; Tucaliuc Oana-Maria; Breabăn Iuliana G.; Crețescu Igor; Nemțoi Gheorghe

2015-01-01

In the present work voltammetric investigations have been performed on HgCl2 aqueous solutions prepared from a Cz 9024 reagent. Carbon paste electrode (CPE), eriochrome black T modified carbon paste electrode (MCPE/EBT) and KCl 1M as background electrolyte, were involved within the experimental procedures. Cyclic voltammetry (CV) has been performed in order to compare the behaviour of the two electrodes in both K3[Fe(CN)6] and mercury calibration aqueous solution. Differential pulse anodic st...

Electrochemical Studies on Minoxidil and Its Determination in Tablets by Differential-Pulse Polarography.

Science.gov (United States)

1984-01-16

full scale and the solution was electrolysed until the digital readout indicated a constant but small count. One hour was required to complete the...buffers were prepared with distilled, deionized water at intervals of 0.5 pH unit over the pH range of 2.6-7.0

Surface Crack Detection for Carbon Fiber Reinforced Plastic Materials Using Pulsed Eddy Current Based on Rectangular Differential Probe

Directory of Open Access Journals (Sweden)

Jialong Wu

2014-01-01

Full Text Available Aiming at the surface defect inspection of carbon fiber reinforced composite, the differential and the direct measurement finite element simulation models of pulsed eddy current flaw detection were built. The principle of differential pulsed eddy current detection was analyzed and the sensitivity of defect detection was compared through two kinds of measurements. The validity of simulation results was demonstrated by experiments. The simulation and experimental results show that the pulsed eddy current detection method based on rectangular differential probe can effectively improve the sensitivity of surface defect detection of carbon fiber reinforced composite material.

Polarographic determination of Sn (II) and total Sn in PYRO and MDP radiopharmaceutical kits

International Nuclear Information System (INIS)

Sebastian, Maria V.A.; Lugon, Marcelo Di M.V.; Silva, Jose L. da; Fukumori, Neuza T.O.; Pereira, Nilda P.S. de; Silva, Constancia P.G. da; Matsuda, Margareth M.N.

2007-01-01

A sensitive, alternative method to atom absorption spectrometry, fluorimetry or potentiometry for the evaluation of tin(II) ions (0.1- 10 mg) and total tin in radiopharmaceutical kits was investigated. Differential pulse polarography was chosen. The supporting electrolyte was H 2 SO 4 3 mol L -1 and HCl 3 mol L -1 solution. The potential was swept from -250 to -800 mV vs Ag/AgCl/saturated KCl, using a dropping mercury electrode with 1 s drop time, 50 mV s -1 scan rate, -50 mV pulse amplitude, 40 ms pulse time and 10 mV step amplitude. Pure nitrogen was used to deaerate the polarographic cell solution for 5 min, before and after each sample introduction. Oxidation of Sn(II) was made in the same sample vial by adding H 2 O 2 (hydrogen peroxide) 10 mol L -1 , at 37 deg C, in order to quantify the total Sn. The calibration curve for Sn(II) and Sn(IV) was obtained in the concentration range of 0-10 ppm from a 1000 ppm standard solution. The detection limit of Sn(II) is 0.5 ppm and for Sn(IV) is 0.6 ppm. Differential pulse polarography was performed in the pyrophosphate (PYRO) and methylenediphosphonic acid (MDP) radiopharmaceutical kits, containing 2 mg and 1 mg of SnCl 2 .2H 2 O per vial, respectively. The described method for determination of stannous ion (Sn(II)), is selective, reproducible and adequate to be used in the quality control of lyophilized reagents and it shall be performed for other cold kits produced at IPEN. (author)

Effects of Pulsed Electromagnetic Field on Differentiation of HUES-17 Human Embryonic Stem Cell Line

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Yi-Lin Wu

2014-08-01

Full Text Available Electromagnetic fields are considered to potentially affect embryonic development, but the mechanism is still unknown. In this study, human embryonic stem cell (hESC line HUES-17 was applied to explore the mechanism of exposure on embryonic development to pulsed electromagnetic field (PEMF for 400 pulses at different electric field intensities and the differentiation of HUES-17 cells was observed after PEMF exposure. The expression of alkaline phosphatase (AP, stage-specific embryonic antigen-3 (SSEA-3, SSEA-4 and the mRNA level and protein level of Oct4, Sox2 and Nanog in HUES-17 cells remained unchanged after PEMF exposure at the electric field intensities of 50, 100, 200 or 400 kV/m. Four hundred pulses PEMF exposure at the electric field intensities of 50, 100, 200 or 400 kV/m did not affect the differentiation of HUES-17 cells. The reason why electromagnetic fields affect embryonic development may be due to other mechanisms rather than affecting the differentiation of embryonic stem cells.

Pulse Retrieval Algorithm for Interferometric Frequency-Resolved Optical Gating Based on Differential Evolution

OpenAIRE

Hyyti, Janne; Escoto, Esmerando; Steinmeyer, Günter

2017-01-01

A novel algorithm for the ultrashort laser pulse characterization method of interferometric frequency-resolved optical gating (iFROG) is presented. Based on a genetic method, namely differential evolution, the algorithm can exploit all available information of an iFROG measurement to retrieve the complex electric field of a pulse. The retrieval is subjected to a series of numerical tests to prove robustness of the algorithm against experimental artifacts and noise. These tests show that the i...

Transient Features in Nanosecond Pulsed Electric Fields Differentially Modulate Mitochondria and Viability

Science.gov (United States)

Beebe, Stephen J.; Chen, Yeong-Jer; Sain, Nova M.; Schoenbach, Karl H.; Xiao, Shu

2012-01-01

It is hypothesized that high frequency components of nanosecond pulsed electric fields (nsPEFs), determined by transient pulse features, are important for maximizing electric field interactions with intracellular structures. For monopolar square wave pulses, these transient features are determined by the rapid rise and fall of the pulsed electric fields. To determine effects on mitochondria membranes and plasma membranes, N1-S1 hepatocellular carcinoma cells were exposed to single 600 ns pulses with varying electric fields (0–80 kV/cm) and short (15 ns) or long (150 ns) rise and fall times. Plasma membrane effects were evaluated using Fluo-4 to determine calcium influx, the only measurable source of increases in intracellular calcium. Mitochondria membrane effects were evaluated using tetramethylrhodamine ethyl ester (TMRE) to determine mitochondria membrane potentials (ΔΨm). Single pulses with short rise and fall times caused electric field-dependent increases in calcium influx, dissipation of ΔΨm and cell death. Pulses with long rise and fall times exhibited electric field-dependent increases in calcium influx, but diminished effects on dissipation of ΔΨm and viability. Results indicate that high frequency components have significant differential impact on mitochondria membranes, which determines cell death, but lesser variances on plasma membranes, which allows calcium influxes, a primary determinant for dissipation of ΔΨm and cell death. PMID:23284682

New hybrid reverse differential pulse position width modulation scheme for wireless optical communication

Science.gov (United States)

Liao, Renbo; Liu, Hongzhan; Qiao, Yaojun

2014-05-01

In order to improve the power efficiency and reduce the packet error rate of reverse differential pulse position modulation (RDPPM) for wireless optical communication (WOC), a hybrid reverse differential pulse position width modulation (RDPPWM) scheme is proposed, based on RDPPM and reverse pulse width modulation. Subsequently, the symbol structure of RDPPWM is briefly analyzed, and its performance is compared with that of other modulation schemes in terms of average transmitted power, bandwidth requirement, and packet error rate over ideal additive white Gaussian noise (AWGN) channels. Based on the given model, the simulation results show that the proposed modulation scheme has the advantages of improving the power efficiency and reducing the bandwidth requirement. Moreover, in terms of error probability performance, RDPPWM can achieve a much lower packet error rate than that of RDPPM. For example, at the same received signal power of -28 dBm, the packet error rate of RDPPWM can decrease to 2.6×10-12, while that of RDPPM is 2.2×10. Furthermore, RDPPWM does not need symbol synchronization at the receiving end. These considerations make RDPPWM a favorable candidate to select as the modulation scheme in the WOC systems.

Pulsed eddy current differential probe to detect the defects in a stainless steel pipe

Science.gov (United States)

Angani, C. S.; Park, D. G.; Kim, C. G.; Leela, P.; Kishore, M.; Cheong, Y. M.

2011-04-01

Pulsed eddy current (PEC) is an electromagnetic nondestructive technique widely used to detect and quantify the flaws in conducting materials. In the present study a differential Hall-sensor probe which is used in the PEC system has been fabricated for the detection of defects in stainless steel pipelines. The differential probe has an exciting coil with two Hall-sensors. A stainless steel test sample with electrical discharge machining (EDM) notches under different depths of 1-5 mm was made and the sample was laminated by plastic insulation having uniform thickness to simulate the pipelines in nuclear power plants (NPPs). The driving coil in the probe is excited by a rectangular current pulse and the resultant response, which is the difference of the two Hall-sensors, has been detected as the PEC probe signal. The discriminating time domain features of the detected pulse such as peak value and time to zero are used to interpret the experimental results with the defects in the test sample. A feature extraction technique such as spectral power density has been devised to infer the PEC response.

Ultra low-noise differential ac-coupled photodetector for sensitive pulse detection applications

International Nuclear Information System (INIS)

Windpassinger, Patrick J; Boisen, Axel; Kjærgaard, Niels; Polzik, Eugene S; Müller, Jörg Helge; Kubasik, Marcin; Koschorreck, Marco

2009-01-01

We report on the performance of ultra low-noise differential photodetectors especially designed for probing of atomic ensembles with weak light pulses. The working principle of the detectors is described together with the analysis procedures employed to extract the photon shot noise of light pulses with ∼1 μs duration. As opposed to frequency response peaked detectors, our approach allows for broadband quantum noise measurements. The equivalent noise charge (ENC) for two different hardware approaches is evaluated to 280 and 340 electrons per pulse, respectively, which corresponds to a dark noise equivalent photon number of n 3dB = 0.8 × 10 5 and n 3dB = 1.2 × 10 5 in the two approaches. Finally, we discuss the possibility of removing classical correlations in the output signal caused by detector imperfection by using double-correlated sampling methods

A differential optical interferometer for measuring short pulses of surface acoustic waves.

Science.gov (United States)

Shaw, Anurupa; Teyssieux, Damien; Laude, Vincent

2017-09-01

The measurement of the displacements caused by the propagation of a short pulse of surface acoustic waves on a solid substrate is investigated. A stabilized time-domain differential interferometer is proposed, with the surface acoustic wave (SAW) sample placed outside the interferometer. Experiments are conducted with surface acoustic waves excited by a chirped interdigital transducer on a piezoelectric lithium niobate substrate having an operational bandwidth covering the 200-400MHz frequency range and producing 10-ns pulses with 36nm maximum out-of-plane displacement. The interferometric response is compared with a direct electrical measurement obtained with a receiving wide bandwidth interdigital transducer and good correspondence is observed. The effects of varying the path difference of the interferometer and the measurement position on the surface are discussed. Pulse compression along the chirped interdigital transducer is observed experimentally. Copyright © 2017 Elsevier B.V. All rights reserved.

Determination of Zalcitabine in Medicaments by Differential Pulse Voltammetry

Directory of Open Access Journals (Sweden)

Katia Christina Leandro

2013-01-01

Full Text Available The zalcitabine (ddC has been extensively used in the treatment of HIV patients due to its antiretroviral activity. The quality control of this active principle in medications is of outstanding importance to public health. The principal objective of the current study was the development of an alternative analytical methodology for the zalcitabine determination using a voltammetric process. The zalcitabine gives a reduction peak (at -1.22 V versus Ag/AgCl at the hanging mercury drop electrode (HMDE. The differential pulse voltammetric response is evaluated with respect to the scan rate (20 mV/s, pulse amplitude (50 mV, support electrolyte (Clark-Lubs buffer, pH (2.0, and other variables. The response is linear over the 10.0 to 28.0 mg/L (47 to 133 μM concentration range, and the detection limit is 2.08 mg/L. The validation of this method was realized using a governmental Brazilian document (Inmetro, 2007 and the results are reported for medication drugs.

Quantitative differentiation of dyes with overlapping one-photon spectra by femtosecond pulse-shaping

International Nuclear Information System (INIS)

Tkaczyk, Eric R.; Tkaczyk, Alan H.; Mauring, Koit; Ye, Jing Yong; Baker, James R.; Norris, Theodore B.

2010-01-01

We demonstrate that DiI and rhodamine B, which are not easily distinguishable to one-photon measurements, can be differentiated and in fact quantified in mixture via tailored two-photon excitation pulses found by a genetic algorithm (GA). A nearly three-fold difference in the ratio of two-photon fluorescence of the two dyes is achieved, without a drop in signal of the favored fluorophore. Implementing an acousto-optic interferometer, we were able to prove that the mechanism of discrimination is second-harmonic tuning by the phase-shaped pulses to the relative maxima and minima of these cross-sections.

[Low-frequency pulsed electromagnetic fields promotes rat osteoblast differentiation in vitro through cAMP/PKA signal pathway].

Science.gov (United States)

Fang, Qing-Qing; Li, Zhi-Zhong; Zhou, Jian; Shi, Wen-Gui; Yan, Juan-Li; Xie, Yan-Fang; Chen, Ke-Ming

2016-11-20

To study whether low-frequency pulsed electromagnetic fields promotes the differentiation of cultured rat osteoblasts through the cAMP/PKA signal pathway. Rat calvarial osteoblasts isolated by enzyme digestion were exposed to 50 Hz 0.6 mT low-frequency pulsed electromagnetic field for varying lengths of time, and the concentration of cAMP and levels of phosphorylated PKA in the cells were assayed. In cells treated with DDA to inhibit the activity of adenylate cyclase, the changes of ALP activity and transcription of osteogenic gene were detected after exposure to low-frequency pulsed electromagnetic field. The changes of osteogenic gene transcription and protein expression were tested in the osteoblasts pretreated with KT5720 in response to low-frequency pulsed electromagnetic field exposure. The intracellular cAMP concentration in the cells increased significantly at 20 min during exposure to low-frequency pulsed electromagnetic field, began to decrease at 40 min during the exposure, and increased again after a 2-h exposure; the same pattern of variation was also observed in p-PKA level. Application of DDA and KT5720 pretreatment both suppressed the increase in ALP activity and osteogenic gene transcription induced by electromagnetic field exposure. Low- frequency pulsed electromagnetic field exposure improves the differentiation of cultured rat osteoblasts by activating cAMP/PKA signal pathway.

Determination of copper in whole blood by differential pulse adsorptive stripping voltammetry

Directory of Open Access Journals (Sweden)

Tarik Attar

2014-02-01

Full Text Available A selective and sensitive method for determination of copper in blood by adsorptive differential pulse cathodic stripping voltammetry is presented. The method is based on adsorptive accumulation of the complexes of Cu (II ions with benzenesulfonyl hydrazide onto hanging mercury drop electrode (HMDE, followed by the reduction of the adsorbed species by differential pulse cathodic stripping voltammetry. The effect of various parameters such as supporting electrolyte, concentration of benzenesulfonyl hydrazide, accumulation potential, accumulation time and stirring rate on the selectivity and sensitivity were studied. The optimum conditions for determination of copper include perchloric acid 0.03 M, concentration of benzenesulfonyl hydrazide 7.5×10-5 M, the accumulation potential of -350 mV (vs. Ag/AgCl, the accumulation time of 50 s, and the scan rate of 50 mV s-1. Under optimized conditions, linear calibration curves were established for the concentration of Cu (II in the range of 0.62-275 ng mL-1, with detection limit of 0.186 ng mL-1 for Cu (II. The procedure was successfully applied to the determination of copper ion in whole blood samples.

Anodic dissolution polarography used for the direct determination of metals in uranium

International Nuclear Information System (INIS)

Bueno, L.A.O.; Abrao, A.

1976-01-01

An electrochemical method of analysis, consisting of pre-concentration and determination of the elements Cd, Pb, Tl, Bi and Cu, present as impurities in uranium salts has been developed. The anodic stripping polarography has been employed using a dropping mercury electrode. The interference of uranium itself in the determination of these elements was eliminated by changing its reduction potential to - 1,0V (with respect to the Ag/AgCl electrode), thus making possible the analysis of the elements that are reduced at more positive potentials. This was achieved by the addition of sufficient amount of K 2 CO 3 to the uranyl chloride solution (in the 4:1 carbonate to uranyl ratio) so as to form the uranyl tricarbonate ([UO 2 (CO 3 ) 3 ] 4- ) complex anion. The supporting electrolyte was the uranyl complex in K 2 CO 3 0,1M. The final concentration of uranium ranged from 2 to 5 g/l. The detection limits for the studied elements varied from 0,08 to 1,27 ppm (μg of the element/gU). This technique has proved to be very convenient since provides sensitivity and precision. The method makes possible the determination of mentioned elements directly in uranium solutions, avoiding any previous chemical separations [pt

DIFFERENTIAL PULSE ANODIC STRIPPING VOLTAMMETRY FOR DETERMINATION OF SOME HEAVY METALS IN URANIUM

Directory of Open Access Journals (Sweden)

Saryati Saryati

2010-06-01

Full Text Available The direct determination of some metals impurity in uranium by using differential pulse anodic stripping voltammetry (DPASV method at a hanging mercury drop electrode and in a carbonate buffer media was developed. It was found that the carbonate buffer show the strongest affinity for uranium and gives the best separation between the DPASV peaks of heavy metals impurities. The carbonate concentration markedly affects the oxidation and reduction the major and the minor constituents of the uranium samples. In 0.1 M carbonate buffer solution pH 10, copper, bismuth, thalium, lead, cadmium, zinc, could be determined without the removal of the uranium matrix. Recovery and relative standard deviation (RSD of this method was in the range of 174% - 85.2% for recovery and 36.8% - 1.2% for RSD. The larger error of analytical result was obtained for Zn at low concentration. In general, the analytic results error and RSD decreased with increasing metals concentration.   Keywords: heavy metal determination, differential pulse anodic stripping voltammetry, uranium

Research on channel characteristics of differential multi pulse position modulation without background noise

Science.gov (United States)

Gao, Zhuo; Zhan, Weida; Sun, Quan; Hao, Ziqiang

2018-04-01

Differential multi-pulse position modulation (DMPPM) is a new type of modulation technology. There is a fast transmission rate, high bandwidth utilization, high modulation rate characteristics. The study of DMPPM modulation has important scientific value and practical significance. Channel capacity is one of the important indexes to measure the communication capability of communication system, and studying the channel capacity of DMPPM without background noise is the key to analyze the characteristics of DMPPM. The DMPPM theoretical model is established. The symbol structure of DMPPM with guard time slot is analyzed, and the channel capacity expression of DMPPM is deduced. Simulation analysis by MATLAB. The curves of unit channel capacity and capacity efficiency at different pulse and photon counting rates are analyzed. The results show that DMPPM is more advantageous than multi-pulse position modulation (MPPM), and is more suitable for future wireless optical communication system.

Practical measurement of silicon in low alloy steels by differential pulse stripping voltammetry

International Nuclear Information System (INIS)

Rahier, A.; Lunardi, S.; Triki, C.

2005-01-01

A sensitive differential pulse anodic stripping voltammetry has been adapted to allow the determination of Si in low-alloy steels using a hanging mercury drop electrode. The method has been qualified using certified ASTM standards and is now running in routine. The present report describes the experimental details, thereby allowing the reader to carry out the measurements precisely. (author)

Amplified fragment length polymorphism and pulsed field gel electrophoresis for subspecies differentiation of Serpulina pilosicoli

DEFF Research Database (Denmark)

Møller, Kristian; Jensen, Tim Kåre; Boye, Mette

1999-01-01

Pulsed field gel electrophoresis (PFGE) and amplified fragment length polymorphism (AFLP) were compared for their ability to differentiate between 50 porcine Serpulina pilosicoli isolates. Both techniques were highly sensitive, dividing the isolates into 36 and 38 groups, respectively. Due...

Time differentiated nuclear resonance spectroscopy coupled with pulsed laser heating in diamond anvil cells

Energy Technology Data Exchange (ETDEWEB)

Kupenko, I., E-mail: kupenko@esrf.fr; Strohm, C. [Bayerisches Geoinstitut, Universität Bayreuth, D-95440 Bayreuth (Germany); ESRF-The European Synchrotron, CS 40220, 38043 Grenoble Cedex 9 (France); McCammon, C.; Cerantola, V.; Petitgirard, S.; Dubrovinsky, L. [Bayerisches Geoinstitut, Universität Bayreuth, D-95440 Bayreuth (Germany); Glazyrin, K. [Photon Science, DESY, D-22607 Hamburg (Germany); Vasiukov, D.; Aprilis, G. [Laboratory of Crystallography, Material Physics and Technology at Extreme Conditions, Universität Bayreuth, D-95440 Bayreuth (Germany); Chumakov, A. I.; Rüffer, R. [ESRF-The European Synchrotron, CS 40220, 38043 Grenoble Cedex 9 (France)

2015-11-15

Developments in pulsed laser heating applied to nuclear resonance techniques are presented together with their applications to studies of geophysically relevant materials. Continuous laser heating in diamond anvil cells is a widely used method to generate extreme temperatures at static high pressure conditions in order to study the structure and properties of materials found in deep planetary interiors. The pulsed laser heating technique has advantages over continuous heating, including prevention of the spreading of heated sample and/or the pressure medium and, thus, a better stability of the heating process. Time differentiated data acquisition coupled with pulsed laser heating in diamond anvil cells was successfully tested at the Nuclear Resonance beamline (ID18) of the European Synchrotron Radiation Facility. We show examples applying the method to investigation of an assemblage containing ε-Fe, FeO, and Fe{sub 3}C using synchrotron Mössbauer source spectroscopy, FeCO{sub 3} using nuclear inelastic scattering, and Fe{sub 2}O{sub 3} using nuclear forward scattering. These examples demonstrate the applicability of pulsed laser heating in diamond anvil cells to spectroscopic techniques with long data acquisition times, because it enables stable pulsed heating with data collection at specific time intervals that are synchronized with laser pulses.

Temporal Profiling and Pulsed SILAC Labeling Identify Novel Secreted Proteins during ex vivo Osteoblast Differentiation of Human Stromal Stem Cells

DEFF Research Database (Denmark)

Kristensen, Lars P; Chen, Li; Nielsen, Maria Overbeck

2012-01-01

, is not fully established. To address these questions, we quantified the temporal dynamics of the human stromal (mesenchymal, skeletal) stem cell (hMSC) secretome during ex vivo OB differentiation using stable isotope labeling by amino acids in cell culture (SILAC). In addition, we employed pulsed SILAC...... the identification of novel factors produced by hMSC with potential role in OB differentiation. Our study demonstrates that the secretome of osteoblastic cells is more complex than previously reported and supports the emerging evidence that osteoblastic cells secrete proteins with endocrine functions and regulate...... regulators of OB differentiation. Furthermore, we studied the biological effects of one of these proteins, the hormone stanniocalcin 2 (STC2) and demonstrated its autocrine effects in enhancing osteoblastic differentiation of hMSC. In conclusion, combining complete and pulsed SILAC labeling facilitated...

Temporal Profiling and Pulsed SILAC Labeling Identify Novel Secreted Proteins During Ex Vivo Osteoblast Differentiation of Human Stromal Stem Cells*

Science.gov (United States)

Kristensen, Lars P.; Chen, Li; Nielsen, Maria Overbeck; Qanie, Diyako W.; Kratchmarova, Irina; Kassem, Moustapha; Andersen, Jens S.

2012-01-01

It is well established that bone forming cells (osteoblasts) secrete proteins with autocrine, paracrine, and endocrine function. However, the identity and functional role for the majority of these secreted and differentially expressed proteins during the osteoblast (OB) differentiation process, is not fully established. To address these questions, we quantified the temporal dynamics of the human stromal (mesenchymal, skeletal) stem cell (hMSC) secretome during ex vivo OB differentiation using stable isotope labeling by amino acids in cell culture (SILAC). In addition, we employed pulsed SILAC labeling to distinguish genuine secreted proteins from intracellular contaminants. We identified 466 potentially secreted proteins that were quantified at 5 time-points during 14-days ex vivo OB differentiation including 41 proteins known to be involved in OB functions. Among these, 315 proteins exhibited more than 2-fold up or down-regulation. The pulsed SILAC method revealed a strong correlation between the fraction of isotope labeling and the subset of proteins known to be secreted and involved in OB differentiation. We verified SILAC data using qRT-PCR analysis of 9 identified potential novel regulators of OB differentiation. Furthermore, we studied the biological effects of one of these proteins, the hormone stanniocalcin 2 (STC2) and demonstrated its autocrine effects in enhancing osteoblastic differentiation of hMSC. In conclusion, combining complete and pulsed SILAC labeling facilitated the identification of novel factors produced by hMSC with potential role in OB differentiation. Our study demonstrates that the secretome of osteoblastic cells is more complex than previously reported and supports the emerging evidence that osteoblastic cells secrete proteins with endocrine functions and regulate cellular processes beyond bone formation. PMID:22801418

Triple-Pulse Integrated Path Differential Absorption Lidar for Carbon Dioxide Measurement - Novel Lidar Technologies and Techniques with Path to Space

Science.gov (United States)

Singh, Upendra N.; Refaat, Tamer F.; Petros, Mulugeta

2017-01-01

The societal benefits of understanding climate change through identification of global carbon dioxide sources and sinks led to the desired NASA's active sensing of carbon dioxide emissions over nights, days, and seasons (ASCENDS) space-based missions of global carbon dioxide measurements. For more than 15 years, NASA Langley Research Center (LaRC) have developed several carbon dioxide active remote sensors using the differential absorption lidar (DIAL) technique operating at the two-micron wavelength. Currently, an airborne two-micron triple-pulse integrated path differential absorption (IPDA) lidar is under development. This IPDA lidar measures carbon dioxide as well as water vapor, the dominant interfering molecule on carbon dioxide remote sensing. Advancement of this triple-pulse IPDA lidar development is presented.

Trace analysis of Cd, Cu, Pb and Zn in various materials using differential pulse anodic stripping voltammetry

International Nuclear Information System (INIS)

Ahmed, R.; Viqar-un-Nisa; Tanwir, R.

1988-09-01

Sampling and sample preparation methods have been described. Digestion methods for different types of materials and acid purification systems have been developed. For trace analysis purposes cleaning methods for glassware etc. have been described. Differential pulse anodic stripping voltametric (DPASV) method has been worked out for the trace analysis of zn, cd, pb and Cu in different types of materials. Linearity of the method has been checked by drawing concentration versus currents (peak height) curves. Precision of the method has been checked by analysing a number of actual samples. of the method has been verified by analysing standards of U.S.A. Comparative studies have been done between Differential pulse anodic stripping voltammetric method and Atomic Absorption spectroscopic method. Problems of contamination and systematic errors during trace and ultra-trace analysis have been discussed. A variety of samples including soil, spinach, wheat flour, rice flour, dry milk, coriander, kidney stones, bladder stones etc. have been analysed and preliminary results have been reported. (author)

Polarographic determination of Iodide and Iodate, in Solutions Coming from Aerosols in Fission Products Containment Studies in Nuclear Power Stations; Determinacion Polarografica de Especies de Iodo (Ioduro y Iodato) en Soluciones Procedentes de Aerosoles, para Estudios de Contencion de Productos de Fision en Centrales Nucleares

Energy Technology Data Exchange (ETDEWEB)

Sanchez, M.; Ballesteros, O.; Fernandez, M.; Clavero, M.; Gonzalez, A. M. [Ciemat, Madrid (Spain)

2000-07-01

A polarographic method is described for the iodine species determination, iodide and iodate in water solutions. the iodate can be determined by differential pulse polarography. Calibration curves and the detection and determination limits have been obtained. Iodides is oxidized to iodate with sodium hypochlorite and the excess of oxidizing agent is destroyed with sodium sulphide. The concentration of iodide is calculated as the difference between the concentration of iodate in the sample before and after the oxidation. As an application, species of iodine in samples coming from the experimental plants GIRS (Gaseous Iodine Removal by Sprays) of Nuclear Fission Department of the CIEMAT, dedicated to fission products containment studies in nuclear power station, were determined. (Author) 10 refs.

Investigations on the application of the ion-exchanger SRAFION NMRR for the enrichment and separation of uranium and other trace elements from sea water

International Nuclear Information System (INIS)

Ochsenkuehn-Petropulu, M.; Parissakis, G.

1985-01-01

It can be demonstrated, in batch and continuous flow experiments that the ion-exchanger SRAFION NMRR is suitable for the preconcentration and separation of uranium and other trace elements (such as Mo, V, Ag, Cr, Cu, Fe, Mn, Ni, Pb and Zn) from sea water. Among the different eluates, 0.5 N HNO 3 was selected. Uranium was extracted from the eluate with 0.1 M TOPO/cyclohexane and analysed in the organic extract by differential-pulse polarography, while the other elements were directly determined in the eluate by AAS. It was possible to determine the above mentioned trace elements by this absorption-elution process in the sea water of the Isthmus of Corinth area, Greece. (orig.) [de

Polarographic studies on the nature of cadmium in scallop, oyster, and lobster

Energy Technology Data Exchange (ETDEWEB)

Chou, C L; Uthe, J F; Zook, E G

1978-04-01

Free and bound forms of cadmium were determined in raw shellfish by use of differential pulse polarography and atomic absorption spectrophotometry. Free cadmium is defined by its polarographic peak potential of -0.62 +- 0.02 V (saturated calomel electrode) in solvent washed ammonium sulfate extracts. Bound cadmium was determined by subtracting the free cadmium from the total cadmium present in the meat. Both scallop (various species) and American lobster (Homarus americanus) muscle tissues contain no free cadmium. Oyster (various species), on the other hand, had a considerable percentage (approximately 50%) of its total cadmium present as free cadmium, a phenomena as yet unexplained. The detection limit for free cadmium is approximately 0.05 ..mu..g/g raw tissue.

Polarographic determination of Iodide and Iodate, in Solutions Coming from Aerosols in Fission Products Containment Studies in Nuclear Power Stations

International Nuclear Information System (INIS)

Sanchez, M.; Ballesteros, O.; Fernandez, M.; Clavero, M.A.; Gonzalez, A.M.

2000-01-01

A polarographic method is described for the iodine species determination, iodide and iodate in water solutions. the iodate can be determined by differential pulse polarography. Calibration curves and the detection and determination limits have been obtained. Iodides is oxidized to iodate with sodium hypochlorite and the excess of oxidizing agent is destroyed with sodium sulphide. The concentration of iodide is calculated as the difference between the concentration of iodate in the sample before and after the oxidation. As an application, species of iodine in samples coming from the experimental plants GIRS (Gaseous Iodine Removal by Sprays) of Nuclear Fission Department of the CIEMAT, dedicated to fission products containment studies in nuclear power station, were determined. (Author) 10 refs

Assessment of cadmium, copper and lead in marine species of the atlantic and pacific oceans of Guatemala by voltametry techniques

International Nuclear Information System (INIS)

Chun, Evelyn

2000-01-01

In this thesis results of measurements of cooper, lead, and cadmium were made using voltametry. Three points in the pacific ocean and one in the atlantic were selected to obtain samples of fish and shrimp as species that are contaminated with toxic metals. The samples were treated by physical and chemical methods to turn soluble the metals and the chemical determination could be done using voltametry or differential polarography of pulse. The results shown that copper, lead and cadmium are present in the samples in traces level. The precision of measurements was verified measuring certified by the National Institute of Standard and Technology NIST of the Commerce Departmento of the United States

Embedded 32-bit Differential Pulse Voltammetry (DPV) Technique for 3-electrode Cell Sensing

Science.gov (United States)

N, Aqmar N. Z.; Abdullah, W. F. H.; Zain, Z. M.; Rani, S.

2018-03-01

This paper addresses the development of differential pulse voltammetry (DPV) embedded algorithm using an ARM cortex processor with new developed potentiostat circuit design for in-situ 3-electrode cell sensing. This project is mainly to design a low cost potentiostat for the researchers in laboratories. It is required to develop an embedded algorithm for analytical technique to be used with the designed potentiostat. DPV is one of the most familiar pulse technique method used with 3-electrode cell sensing in chemical studies. Experiment was conducted on 10mM solution of Ferricyanide using the designed potentiostat and the developed DPV algorithm. As a result, the device can generate an excitation signal of DPV from 0.4V to 1.2V and produced a peaked voltammogram with relatively small error compared to the commercial potentiostat; which is only 6.25% difference in peak potential reading. The design of potentiostat device and its DPV algorithm is verified.

Electrochemical analysis

International Nuclear Information System (INIS)

Hwang, Hun

2007-02-01

This book explains potentiometry, voltametry, amperometry and basic conception of conductometry with eleven chapters. It gives the specific descriptions on electrochemical cell and its mode, basic conception of electrochemical analysis on oxidation-reduction reaction, standard electrode potential, formal potential, faradaic current and faradaic process, mass transfer and overvoltage, potentiometry and indirect potentiometry, polarography with TAST, normal pulse and deferential pulse, voltammetry, conductometry and conductometric titration.

Differential pulse anodic stripping voltametry for ultratrace determination of cadmium and lead in Antarctic snow

International Nuclear Information System (INIS)

Scarponi, G.; Barbante, C.; Cescon, P.

1994-01-01

Differential pulse anodic stripping voltametry has sufficient sensitivity to be used for direct determination of heavy metals in Antarctic snow, thus avoiding long and contamination-prone enrichment procedures. A result of particular concern to global change studies can be drawn from these preliminary data: lead concentration in Antarctic snow decreased rapidly during the 1980s from about 10-15 pg/g to 2-4 pg/g in 1991. (authors). 16 refs., 3 figs., 1 tab

Airborne 2-Micron Double-Pulsed Integrated Path Differential Absorption Lidar for Column CO2 Measurement

Science.gov (United States)

Singh, Upendra N.; Yu, Jirong; Petros, Mulugeta; Refaat, Tamer F.; Remus, Ruben G.; Fay, James J.; Reithmaier, Karl

2014-01-01

Double-pulse 2-micron lasers have been demonstrated with energy as high as 600 millijouls and up to 10 Hz repetition rate. The two laser pulses are separated by 200 microseconds and can be tuned and locked separately. Applying double-pulse laser in DIAL system enhances the CO2 measurement capability by increasing the overlap of the sampled volume between the on-line and off-line. To avoid detection complicity, integrated path differential absorption (IPDA) lidar provides higher signal-to-noise ratio measurement compared to conventional range-resolved DIAL. Rather than weak atmospheric scattering returns, IPDA rely on the much stronger hard target returns that is best suited for airborne platforms. In addition, the IPDA technique measures the total integrated column content from the instrument to the hard target but with weighting that can be tuned by the transmitter. Therefore, the transmitter could be tuned to weight the column measurement to the surface for optimum CO2 interaction studies or up to the free troposphere for optimum transport studies. Currently, NASA LaRC is developing and integrating a double-Pulsed 2-micron direct detection IPDA lidar for CO2 column measurement from an airborne platform. The presentation will describe the development of the 2-micron IPDA lidar system and present the airborne measurement of column CO2 and will compare to in-situ measurement for various ground target of different reflectivity.

Parameters affecting the determination of paraquat at silver rotating electrodes using differential pulse voltammetry

Directory of Open Access Journals (Sweden)

A. Farahi

2014-08-01

Full Text Available The electrochemical determination of aqueous paraquat PQ(II by differential pulse voltammetry at a solid rotating silver electrode (RSE is described. The aim of this work is to optimize all factors that can influence this determination. Potential wave forms, potential scan parameters and deposition time were examined for their effect on the paraquat peak shape and intensity. The best responses were obtained with differential pulse voltammetry in 0.1 mol L−1 Na2SO4 as supporting electrolyte using amplitude 50 mV, scan increment 5 mV, deposition time 120 s, frequency 50 s−1 and step amplitude 0.05 V. Electrochemical and mechanical surface cleaning, aimed at removing the amount of paraquat deposited onto the silver surface, were necessary for obtaining a good performance of the electrode. Response linearity, repeatability, accuracy and detection limit were also evaluated. The obtained detection limits were 7.1 × 10−9 mol L−1 and 2.8 × 10−9 mol L−1 for peak 1 and peak 2 respectively. The relative standard deviation (RSD was found to be 1.19% in 1.0 × 10−4 mol L−1 paraquat. The applicability of the RSE for PQ(II determination in milk samples, without any sample pretreatment, was successfully demonstrated.

Low-intensity pulsed ultrasound regulates proliferation and differentiation of osteoblasts through osteocytes

International Nuclear Information System (INIS)

Li, Lei; Yang, Zheng; Zhang, Hai; Chen, Wenchuan; Chen, Mengshi; Zhu, Zhimin

2012-01-01

Highlights: ► CM from LIPUS-stimulated osteocytes inhibits proliferation of osteoblasts. ► CM from LIPUS-stimulated osteocytes enhances differentiation of osteoblasts. ► LIPUS stimulates MLO-Y4 cells to secrete PGE 2 and NO. -- Abstract: Low-intensity pulsed ultrasound (LIPUS) has been used as a safe and effective modality to enhance fracture healing. As the most abundant cells in bone, osteocytes orchestrate biological activities of effector cells via direct cell-to-cell contacts and by soluble factors. In this study, we have used the osteocytic MLO-Y4 cells to study the effects of conditioned medium from LIPUS-stimulated MLO-Y4 cells on proliferation and differentiation of osteoblastic MC3T3-E1 cells. Conditioned media from LIPUS-stimulated MLO-Y4 cells (LIPUS-Osteocyte-CM) were collected and added on MC3T3-E1 cell cultures. MC3T3-E1 cells cultured in LIPUS-Osteocyte-CM demonstrated a significant inhibition of proliferation and an increased alkaline phosphatase activity. The results of PGE 2 and NO assay showed that LIPUS could enhance PGE 2 and NO secretion from MLO-Y4 cells at all time points within 24 h after LIPUS stimulation. We conclude that LIPUS regulates proliferation and differentiation of osteoblasts through osteocytes in vitro. Increased secretion of PGE 2 from osteocytes may play a role in this effect.

Nanosecond electric pulses differentially affect inward and outward currents in patch clamped adrenal chromaffin cells.

Directory of Open Access Journals (Sweden)

Lisha Yang

Full Text Available This study examined the effect of 5 ns electric pulses on macroscopic ionic currents in whole-cell voltage-clamped adrenal chromaffin cells. Current-voltage (I-V relationships first established that the early peak inward current was primarily composed of a fast voltage-dependent Na+ current (INa, whereas the late outward current was composed of at least three ionic currents: a voltage-gated Ca2+ current (ICa, a Ca2+-activated K+ current (IK(Ca, and a sustained voltage-dependent delayed rectifier K+ current (IKV. A constant-voltage step protocol was next used to monitor peak inward and late outward currents before and after cell exposure to a 5 ns pulse. A single pulse applied at an electric (E-field amplitude of 5 MV/m resulted in an instantaneous decrease of ~4% in peak INa that then declined exponentially to a level that was ~85% of the initial level after 10 min. Increasing the E-field amplitude to 8 or 10 MV/m caused a twofold greater inhibitory effect on peak INa. The decrease in INa was not due to a change in either the steady-state inactivation or activation of the Na+ channel but instead was associated with a decrease in maximal Na+ conductance. Late outward current was not affected by a pulse applied at 5 MV/m. However, for a pulse applied at the higher E-field amplitudes of 8 and 10 MV/m, late outward current in some cells underwent a progressive ~22% decline over the course of the first 20 s following pulse exposure, with no further decline. The effect was most likely concentrated on ICa and IK(Ca as IKV was not affected. The results of this study indicate that in whole-cell patch clamped adrenal chromaffin cells, a 5 ns pulse differentially inhibits specific voltage-gated ionic currents in a manner that can be manipulated by tuning E-field amplitude.

Pulsed electromagnetic fields promote the proliferation and differentiation of osteoblasts by reinforcing intracellular calcium transients.

Science.gov (United States)

Tong, Jie; Sun, Lijun; Zhu, Bin; Fan, Yun; Ma, Xingfeng; Yu, Liyin; Zhang, Jianbao

2017-10-01

Pulsed electromagnetic fields (PEMF) can be used to treat bone-related diseases, but the underlying mechanism remains unclear, especially the process by which PEMFs initiate biological effects. In this study, we demonstrated the effects of PEMF on proliferation and differentiation of osteoblasts using the model of calcium transients induced by high extracellular calcium. Our results showed that PEMF can increase both the percentage of responding cells and amplitude of intracellular calcium transients induced by high extracellular calcium stimulation. Compared with corresponding extracellular calcium levels, PEMF stimulation increased proliferation and differentiation of osteoblasts and related gene expressions, such as insulin-like growth factor 1 (IGF-1), alkaline phosphatase (ALP), runt-related transcription factor 2 (Runx2), and osteocalcin (OCN), which can be completely abolished by BAPTA-AM. Moreover, PEMF did not affect proliferation and differentiation of osteoblasts if no intracellular calcium transient was present in osteoblasts during PEMF exposure. Our results revealed that PEMF affects osteoblast proliferation and differentiation through enhanced intracellular calcium transients, which provided a cue to treat bone-related diseases with PEMF. Bioelectromagnetics. 38:541-549, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

Ruthenium-modified cytochrome c: temperature dependence of the rate of intramolecular electron transfer

International Nuclear Information System (INIS)

Isied, S.S.; Kuehn, C.; Worosila, G.

1984-01-01

The ruthenium-modified horse heart cytochrome c, Ru(III)-cyt c(III), where the ruthenium is bound to the histidines-33 residue has been synthesized and characterized by ruthenium analysis, UV-vis and CD spectra, and differential pulse polarography and cyclic voltammetry. The intermediate Ru(III)-cyt c(III) has been generated by pulse-radioanalysis with use of four different radicals, CO 2 -., (CH 3 )COH., (CH 2 OH) 3 CCHOH, and -OCCH(OH)C(OH)CO 2 -. The rate of intramolecular electron transfer within the Ru(III)-cyt c(III) complex and its temperature dependence were determined over a 40 0 C temperature range with the CO 2 -. radical. At 25 0 C, these values are k/sub u/=53 +/- s/sup -1/ (pH 7.01 M phosphate buffer, 0.1 M NaHCO 2 ), ΔH/sup +/=3.5 +/- 0.2 kcal mol/sup -1/, and ΔS/sup +/=-39 +/- 1 eu

Validation of double-pulse 1572 nm integrated path differential absorption lidar measurement of carbon dioxide

Science.gov (United States)

Du, Juan; Liu, Jiqiao; Bi, Decang; Ma, Xiuhua; Hou, Xia; Zhu, Xiaolei; Chen, Weibiao

2018-04-01

A ground-based double-pulse 1572 nm integrated path differential absorption (IPDA) lidar was developed for carbon dioxide (CO2) column concentrations measurement. The lidar measured the CO2 concentrations continuously by receiving the scattered echo signal from a building about 1300 m away. The other two instruments of TDLAS and in-situ CO2 analyzer measured the CO2 concentrations on the same time. A CO2 concentration measurement of 430 ppm with 1.637 ppm standard error was achieved.

Differential Pulse Anodic Stripping Voltammetry for Mercury Determination

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Vereștiuc Paul C.

2015-07-01

Full Text Available In the present work voltammetric investigations have been performed on HgCl2 aqueous solutions prepared from a Cz 9024 reagent. Carbon paste electrode (CPE, eriochrome black T modified carbon paste electrode (MCPE/EBT and KCl 1M as background electrolyte, were involved within the experimental procedures. Cyclic voltammetry (CV has been performed in order to compare the behaviour of the two electrodes in both K3[Fe(CN6] and mercury calibration aqueous solution. Differential pulse anodic stripping voltammetry (DPASV was used to determine the most suitable parameters for mercury determination. All experiments were performed at 25 ± 1 ℃, using an electrochemical cell with three-electrodes connected to an Autolab PG STAT 302N (Metrohm-Autolab potentiostat that is equipped with Nova 1.11 software. The measured potential values were generated by using the silver chloride electrode (AgClE as reference and a platinum wire electrode as auxiliary. A series of time depending equations for the pre-concentration and concentration steps were established, with the observation that a higher sensitivity can be obtained while increasing the pre-concentration time. DPASV were drawn using the CPE in 11.16 % coriander, as mercury complex, the voltamograms signals indicating mercury oxidation, with signal intensity increasing in time.

Determination of Selenium in infant formula by differential pulse cathodic stripping voltammetry

Directory of Open Access Journals (Sweden)

"Oveisi MR

2002-07-01

Full Text Available Selenium as a nonmetallic chemical element has received high attention of biologists because of its dual role as an essential trace nutrient and a toxic element. This interest has created a need for reliable analytical methods for determination of selenium. In this investigation determination of selenium by differential pulse cathodic stripping voltammetry and the influence of various parameters such as deposition potentials, deposition time. Cu concentration pH, etc. on selenium peak in voltammogram are described. Determination of selenium was accomplished in mixture of acetic acid, hydrochloric acid and sodium chloride buffer (pH=1 with a scan rate of 60 mv/s and a pulse height of 100 my by hanging mercury drop electrode (HMDE as working electrode. The solution was stirred during pre-electrolysis at - 350 mv (vs SCE for 30 s and the potential was scanned between - 350 mv and - 800 mv. The determination limit of the method was 0.005 mg/kg for the sample. The calibration curves were linear in the range of 0-30 μg/L (R2=0.996, p<0.001. Repeatability of the method at concentrations of 30 and 0.5 μg/L were 2.5 and 10.5% respectively.

Low-intensity pulsed ultrasound regulates proliferation and differentiation of osteoblasts through osteocytes

Energy Technology Data Exchange (ETDEWEB)

Li, Lei, E-mail: geraldleelei@163.com [State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu (China); Yang, Zheng [State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu (China); Zhang, Hai [Department of Restorative Dentistry, School of Dentistry, University of Washington, Seattle, WA (United States); Chen, Wenchuan [State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu (China); Chen, Mengshi [Department of Biomechanics, Sichuan University, Chengdu (China); Zhu, Zhimin, E-mail: hxzhimin@163.com [State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu (China)

2012-02-10

Highlights: Black-Right-Pointing-Pointer CM from LIPUS-stimulated osteocytes inhibits proliferation of osteoblasts. Black-Right-Pointing-Pointer CM from LIPUS-stimulated osteocytes enhances differentiation of osteoblasts. Black-Right-Pointing-Pointer LIPUS stimulates MLO-Y4 cells to secrete PGE{sub 2} and NO. -- Abstract: Low-intensity pulsed ultrasound (LIPUS) has been used as a safe and effective modality to enhance fracture healing. As the most abundant cells in bone, osteocytes orchestrate biological activities of effector cells via direct cell-to-cell contacts and by soluble factors. In this study, we have used the osteocytic MLO-Y4 cells to study the effects of conditioned medium from LIPUS-stimulated MLO-Y4 cells on proliferation and differentiation of osteoblastic MC3T3-E1 cells. Conditioned media from LIPUS-stimulated MLO-Y4 cells (LIPUS-Osteocyte-CM) were collected and added on MC3T3-E1 cell cultures. MC3T3-E1 cells cultured in LIPUS-Osteocyte-CM demonstrated a significant inhibition of proliferation and an increased alkaline phosphatase activity. The results of PGE{sub 2} and NO assay showed that LIPUS could enhance PGE{sub 2} and NO secretion from MLO-Y4 cells at all time points within 24 h after LIPUS stimulation. We conclude that LIPUS regulates proliferation and differentiation of osteoblasts through osteocytes in vitro. Increased secretion of PGE{sub 2} from osteocytes may play a role in this effect.

Detection of Individual Molecules and Ions by Carbon Nanotube-Based Differential Resistive Pulse Sensor.

Science.gov (United States)

Peng, Ran; Tang, Xiaowu Shirley; Li, Dongqing

2018-04-01

This paper presents a new method of sensing single molecules and cations by a carbon nanotube (CNT)-based differential resistive pulse sensing (RPS) technique on a nanofluidic chip. A mathematical model for multichannel RPS systems is developed to evaluate the CNT-based RPS signals. Individual cations, rhodamine B dye molecules, and ssDNAs are detected successfully with high resolution and high signal-to-noise ratio. Differentiating ssDNAs with 15 and 30 nucleotides are achieved. The experimental results also show that translocation of negatively charged ssDNAs through a CNT decreases the electrical resistance of the CNT channel, while translocation of positively charged cations and rhodamine B molecules increases the electrical resistance of the CNT. The CNT-based nanofluidic device developed in this work provides a new avenue for single-molecule/ion detection and offers a potential strategy for DNA sequencing. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Simultaneous determination of three herbicides by differential pulse voltammetry and chemometrics.

Science.gov (United States)

Ni, Yongnian; Wang, Lin; Kokot, Serge

2011-01-01

A novel differential pulse voltammetry method (DPV) was researched and developed for the simultaneous determination of Pendimethalin, Dinoseb and sodium 5-nitroguaiacolate (5NG) with the aid of chemometrics. The voltammograms of these three compounds overlapped significantly, and to facilitate the simultaneous determination of the three analytes, chemometrics methods were applied. These included classical least squares (CLS), principal component regression (PCR), partial least squares (PLS) and radial basis function-artificial neural networks (RBF-ANN). A separately prepared verification data set was used to confirm the calibrations, which were built from the original and first derivative data matrices of the voltammograms. On the basis relative prediction errors and recoveries of the analytes, the RBF-ANN and the DPLS (D - first derivative spectra) models performed best and are particularly recommended for application. The DPLS calibration model was applied satisfactorily for the prediction of the three analytes from market vegetables and lake water samples.

Differential discriminator

International Nuclear Information System (INIS)

Dukhanov, V.I.; Mazurov, I.B.

1981-01-01

A principal flowsheet of a differential discriminator intended for operation in a spectrometric circuit with statistical time distribution of pulses is described. The differential discriminator includes four integrated discriminators and a channel of piled-up signal rejection. The presence of the rejection channel enables the discriminator to operate effectively at loads of 14x10 3 pulse/s. The temperature instability of the discrimination thresholds equals 250 μV/ 0 C. The discrimination level changes within 0.1-5 V, the level shift constitutes 0.5% for the filling ratio of 1:10. The rejection coefficient is not less than 90%. Alpha spectrum of the 228 Th source is presented to evaluate the discriminator operation with the rejector. The rejector provides 50 ns time resolution

Selenium and Trace Element Distribution in Astragalus Plants: Developing a Differential Pulse Polarographic Method for Their Determination

OpenAIRE

SOMER, Güler; ÇALIŞKAN, A. Cengiz

2007-01-01

Astragalus plants have a wide range of applications in pharmaceuticals (gum tragacanth), as thickening agents in foods, and may have applications in controlling cancer cells. They are used as feed for animals and they are indicator plants for selenium. Because of their use in health-related areas it is very important to determine their selenium and trace element content with high accuracy. A new differential pulse polarographic method was established for trace element determination (...

Differential Amplitude Pulse-Position Modulation for Indoor Wireless Optical Communications

Directory of Open Access Journals (Sweden)

Sethakaset Ubolthip

2005-01-01

Full Text Available We propose a novel differential amplitude pulse-position modulation (DAPPM for indoor optical wireless communications. DAPPM yields advantages over PPM, DPPM, and DH-PIM in terms of bandwidth requirements, capacity, and peak-to-average power ratio (PAPR. The performance of a DAPPM system with an unequalized receiver is examined over nondispersive and dispersive channels. DAPPM can provide better bandwidth and/or power efficiency than PAM, PPM, DPPM, and DH-PIM depending on the number of amplitude levels and the maximum length of a symbol. We also show that, given the same maximum length, DAPPM has better bandwidth efficiency but requires about and more power than PPM and DPPM, respectively, at high bit rates over a dispersive channel. Conversely, DAPPM requires less power than DH-PIM . When the number of bits per symbol is the same, PAM requires more power, and DH-PIM less power, than DAPPM. Finally, it is shown that the performance of DAPPM can be improved with MLSD, chip-rate DFE, and multichip-rate DFE.

Electrochemical Performances of Diamond Like Carbon Films for Pb(II) Detection in Tap Water Using Differential Pulse Anodic Stripping Voltammetry Technique

Czech Academy of Sciences Publication Activity Database

Sbartai, A.; Namour, F.; Barbier, F.; Krejčí, J.; Kučerová, R.; Krejčí, T.; Neděla, Vilém; Sobota, Jaroslav; Jaffrezic-Renault, N.

2013-01-01

Roč. 11, č. 8 (2013), s. 1524-1529 ISSN 1546-198X Institutional support: RVO:68081731 Keywords : Diamond Like Carbon DLC * Lead Detection * Differential Pulse Anodic Stripping * Voltammetry * Tap Water Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering Impact factor: 0.558, year: 2013

Pulsed magnetic therapy increases osteogenic differentiation of mesenchymal stem cells only if they are pre-committed.

Science.gov (United States)

Ferroni, Letizia; Tocco, Ilaria; De Pieri, Andrea; Menarin, Martina; Fermi, Enrico; Piattelli, Adriano; Gardin, Chiara; Zavan, Barbara

2016-05-01

Pulsed electromagnetic field (PEMF) therapy has been documented to be an effective, non-invasive, safe treatment method for a variety of clinical conditions, especially in settings of recalcitrant healing. The underlying mechanisms on the different biological components of tissue regeneration are still to be elucidated. The aim of the present study was to characterize the effects of extremely low frequency (ELF)-PEMFs on commitment of mesenchymal stem cell (MSCs) culture system, through the determination of gene expression pattern and cellular morphology. Human MSCs derived from adipose tissue (ADSCs) were cultured in presence of adipogenic, osteogenic, neural, or glial differentiative medium and basal medium, then exposed to ELF-PEMFs daily stimulation for 21days. Control cultures were performed without ELF-PEMFs stimulation for all cell populations. Effects on commitment were evaluated after 21days of cultures. The results suggested ELF-PEMFs does not influence ADSCs commitment and does not promote adipogenic, osteogenic, neural or glial differentiation. However, ELF-PEMFs treatment on ADSCs cultured in osteogenic differentiative medium markedly increased osteogenesis. We concluded that PEMFs affect the osteogenic differentiation of ADSCs only if they are pre-commitment and that this therapy can be an appropriate candidate for treatment of conditions requiring an acceleration of repairing process. Copyright © 2016 Elsevier Inc. All rights reserved.

Polytetrafluorethylene film-based liquid-three phase micro extraction coupled with differential pulse voltammetry for the determination of atorvastatin calcium.

Science.gov (United States)

Ensafi, Ali A; Khoddami, Elaheh; Rezaei, Behzad

2013-01-01

In this paper, we describe a new combination method based on polytetrafluorethylene (PTFE) film-based liquid three-phase micro extraction coupled with differential pulse voltammetry (DPV) for the micro extraction and quantification of atorvastatin calcium (ATC) at the ultra-trace level. Different factors affecting the liquid-three phases micro extraction of atorvastatin calcium, including organic solvent, pH of the donor and acceptor phases, concentration of salt, extraction time, stirring rate and electrochemical factors, were investigated, and the optimal extraction conditions were established. The final stable signal was achieved after a 50 min extraction time, which was used for analytical applications. An enrichment factor of 21 was achieved, and the relative standard deviation (RSD) of the method was 4.5% (n = 4). Differential pulse voltammetry exhibited two wide linear dynamic ranges of 20.0-1000.0 pmol L(-1) and 0.001-11.0 µmol L(-1) of ATC. The detection limit was found to be 8.1 pmol L(-1) ATC. Finally, the proposed method was used as a new combination method for the determination of atorvastatin calcium in real samples, such as human urine and plasma.

The Graphene/l-Cysteine/Gold-Modified Electrode for the Differential Pulse Stripping Voltammetry Detection of Trace Levels of Cadmium

OpenAIRE

Yu Song; Chao Bian; Jianhua Tong; Yang Li; Shanghong Xia

2016-01-01

Cadmium(II) is a common water pollutant with high toxicity. It is of significant importance for detecting aqueous contaminants accurately, as these contaminants are harmful to human health and environment. This paper describes the fabrication, characterization, and application of an environment-friendly graphene (Gr)/l-cysteine/gold electrode to detect trace levels of cadmium (Cd) by differential pulse stripping voltammetry (DPSV). The influence of hydrogen overflow was decreased and the curr...

A two-level voltage source inverter with differentially sinusoidal pulse width modulation used in the interconnection system of a wind turbine generator

Directory of Open Access Journals (Sweden)

Alexandros C. Charalampidis

2014-10-01

Full Text Available This study analyses an interconnection system based on differentially sinusoidal pulse width modulation, used for the interconnection to the grid of a variable speed wind turbine. The modulation technique used provides specific advantages in comparison with the commonly used sinusoidal pulse width modulation (SPWM technique, such as lower DC bus voltage requirements, smaller switching losses for the same switching frequency as well as less higher harmonic content in the voltage waveforms produced. The respective control system is also described in detail. Thus this study provides a guide enabling the design of any interconnection system based on this modulation technique.

Determination of the wavelength dependence of the differential pathlength factor from near-infrared pulse signals

Science.gov (United States)

Kohl, Matthias; Nolte, Christian; Heekeren, Hauke R.; Horst, Susanne; Scholz, Udo; Obrig, Hellmuth; Villringer, Arno

1998-06-01

For the calculation of changes in oxyhaemoglobin, deoxyhaemoglobin and the redox state of cytochrome-c-oxidase from attenuation data via a modified Beer-Lambert equation the wavelength dependence of the differential pathlength factor (DPF) has to be taken into account. The DPF, i.e. the ratio of the mean optical pathlength and the physical light source-detector separation at each wavelength, determines the crosstalk between the different concentrations and is therefore essential for a sensitive detection of chromophore changes. Here a simple method is suggested to estimate the wavelength dependence of the DPF from pulse-induced attenuation changes measured on the head of adult humans. The essence is that the DPF is the ratio of the attenuation changes over absorption coefficient changes, and that the spectral form of the pulse correlated absorption coefficient change can be assumed to be proportional to the extinction coefficient of blood. Indicators for the validity of the DPF derived for wavelengths between 700 and 970 nm are the stability of the calculated haemoglobin and cytochrome signals with variations of the wavelength range included for their calculation and its overall agreement with the data available from the literature.

Imprinted polymer-modified hanging mercury drop electrode for differential pulse cathodic stripping voltammetric analysis of creatine.

Science.gov (United States)

Lakshmi, Dhana; Sharma, Piyush S; Prasad, Bhim B

2007-06-15

The molecularly imprinted polymer [poly(p-aminobenzoicacid-co-1,2-dichloroethane)] film casting was made on the surface of a hanging mercury drop electrode by drop-coating method for the selective and sensitive evaluation of creatine in water, blood serum and pharmaceutical samples. The molecular recognition of creatine by the imprinted polymer was found to be specific via non-covalent (electrostatic) imprinting. The creatine binding could easily be detected by differential pulse, cathodic stripping voltammetric signal at optimised operational conditions: accumulation potential -0.01 V (versus Ag/AgCl), polymer deposition time 15s, template accumulation time 60s, pH 7.1 (supporting electrolyte< or =5 x 10(-4)M NaOH), scan rate 10 mV s(-1), pulse amplitude 25 mV. The modified sensor in the present study was found to be highly reproducible and selective with detection limit 0.11 ng mL(-1) of creatine. Cross-reactivity studies revealed no response to the addition of urea, creatinine and phenylalanine; however, some insignificant magnitude of current was observed for tryptophan and histidine in the test samples.

Concave pulse shaping of a circularly polarized laser pulse from non-uniform overdense plasmas

Energy Technology Data Exchange (ETDEWEB)

Hur, Min Sup [School of Natural Science, UNIST, BanYeon-Ri 100, Ulju-gun, Ulsan, 689-798 (Korea, Republic of); Kulagin, Victor V. [Sternberg Astronomical Institute, Moscow State University, Universitetsky prosp. 13, Moscow, 119992 (Russian Federation); Suk, Hyyong, E-mail: hysuk@gist.ac.kr [Department of Physics and Photon Science, GIST, 123 Cheomdan-gwangiro, Buk-gu, Gwangju, 500-712 (Korea, Republic of)

2015-03-20

Pulse shaping of circularly polarized laser pulses in nonuniform overdense plasmas are investigated numerically. Specifically we show by two-dimensional particle-in-cell simulations the generation of a concave pulse front of a circularly polarized, a few tens of petawatt laser pulse from a density-tapered, overdense plasma slab. The concept used for the transverse-directional shaping is the differential transmittance depending on the plasma density, and the laser intensity. For suitable selection of the slab parameters for the concave pulse shaping, we studied numerically the pulse transmittance, which can be used for further parameter design of the pulse shaping. The concavely shaped circularly polarized pulse is expected to add more freedom in controlling the ion-beam characteristics in the RPDA regime. - Highlights: • Laser pulse shaping for a concave front by non-uniform overdense plasma was studied. • Particle-in-cell (PIC) simulations were used for the investigation. • A laser pulse can be shaped by a density-tapered overdense plasma. • The concave and sharp pulse front are useful in many laser–plasma applications. • They are important for ion acceleration, especially in the radiation pressure dominant regime.

Determination of lead and cadmium in biological materials

International Nuclear Information System (INIS)

Stoeppler, M.; Backhaus, F.; Dahl, R.; Hagedorn-Goetz, H.; Hilpert, K.; Klahre, P.; Rutzel, H.; Valenta, P.; Nuernberg, H.W.; Dumont, M.

1975-01-01

Sampling techniques and experience, and decomposition methods are presented. The processes used in flameless atomic absorption spectrometry (including the method using automatic insertion of samples), pulse polarography and isotope dilution mass spectrometry are described. Finally, the results of lead and cadmium measurements in bovine liver, blood, urine and hair samples are reported and discussed with a comparison of methods in some cases

Stability of Benzotriazole Derivatives with Free Cu, Zn, Co and Metal-Containing Enzymes: Binding and Interaction of Methylbenzotriazoles with Superoxide Dismutase and Vitamin B12

Science.gov (United States)

Abudalo, R. A.; AbuDalo, M. A.; Hernandez, M. T.

2018-02-01

Benzotriazole derivatives form very strong bonds with transition metals, and are the most widely used type of industrial corrosion inhibitor. Some benzotriazole derivatives have been implicated as hormone regulators which also carry the ability to induce uncoupling responses or otherwise inhibit respiration processes in some microorganisms. However, the mechanisms associated with benzotriazole toxicity and inhibition are unknown. Using Differential Pulse Polarography, the stability constants of commercially significant corrosion inhibitors, 4-and 5-methylbenzotriazole, coordinated with free Cu (II) and Co (III), were determined to be 1015 and 108, respectively. Polarographic analyses were extended to confirm that methylbenzotriazole also binds the copper center(s) in the ubiquitous enzyme superoxide dismutase, and the Corrin site in the coenzyme cobalamin (vitamin B12). These results suggest that the metal-chelating ability of this unique class of compounds may confer inhibition to certain enzyme systems.

Direct and indirect methods for the determination of vitamin K3 using differential pulse polarography and application to pharmaceuticals.

Science.gov (United States)

Somer, Güler; Doğan, Mehmet

2008-11-01

Two methods for the determination of vitamin K(3) have been developed. Vitamin K(3) in its oxidized form is determined by direct and indirect methods. Its standard solution was prepared by the indirect method using Ti(III) as reducing agent. For this purpose vitamin K(3) (menadion) in a clinical injection solution, which is in its hydroquinone form in the presence of sulfite, is oxidized with oxygen. In 0.2 M HAc and 0.02 M HCl electrolyte vitamin K(3) and Ti(IV) have reduction peaks at -0.58 V at -0.82 V respectively. The reaction between Ti(III) and vitamin takes place quantitatively in a medium of 0.2 M HAc and 0.002 M HCl. After the reduction, the reaction product Ti(IV) is followed from its polarographic peak at about -0.82 V. The most important result in this work is that, with this method vitamin K(3) can be standardized and after standardization this solution can be used for the direct determination in routine analysis with a very simple and fast method, using only the peak at -0.71 V in 0.2 M HAc medium. Both direct and indirect methods have been used for the determination of Vitamin K(3) in a clinical injection solution. The limit of quantification (LOQ) was 1.5x10(-6) M and in both methods the detection limit found was 7x10(-7) M.

Characterization of an electrochemical mercury sensor using alternating current, cyclic, square wave and differential pulse voltammetry

International Nuclear Information System (INIS)

Guerreiro, Gabriela V.; Zaitouna, Anita J.; Lai, Rebecca Y.

2014-01-01

Graphical abstract: -- Highlights: •An electrochemical Hg(II) sensor based on T–Hg(II)–T sensing motif was fabricated. •A methylene blue-modified DNA probe was used to fabricate the sensor. •Sensor performance was evaluated using ACV, CV, SWV, and DPV. •The sensor behaves as a “signal-off” sensor in ACV and CV. •The sensor behaves as either a “signal-on” or “signal-off” sensor in SWV and DPV. -- Abstract: Here we report the characterization of an electrochemical mercury (Hg 2+ ) sensor constructed with a methylene blue (MB)-modified and thymine-containing linear DNA probe. Similar to the linear probe electrochemical DNA sensor, the resultant sensor behaved as a “signal-off” sensor in alternating current voltammetry and cyclic voltammetry. However, depending on the applied frequency or pulse width, the sensor can behave as either a “signal-off” or “signal-on” sensor in square wave voltammetry (SWV) and differential pulse voltammetry (DPV). In SWV, the sensor showed “signal-on” behavior at low frequencies and “signal-off” behavior at high frequencies. In DPV, the sensor showed “signal-off” behavior at short pulse widths and “signal-on” behavior at long pulse widths. Independent of the sensor interrogation technique, the limit of detection was found to be 10 nM, with a linear dynamic range between 10 nM and 500 nM. In addition, the sensor responded to Hg 2+ rather rapidly; majority of the signal change occurred in 2+ , which has not been previously reported. More importantly, the observed “switching” behavior in SWV and DPV is potentially generalizable and should be applicable to most sensors in this class of dynamics-based electrochemical biosensors

2-Micron Triple-Pulse Integrated Path Differential Absorption Lidar Development for Simultaneous Airborne Column Measurements of Carbon Dioxide and Water Vapor in the Atmosphere

Science.gov (United States)

Singh, Upendra N.; Petros, Mulugeta; Refaat, Tamer F.; Yu, Jirong

2016-01-01

For more than 15 years, NASA Langley Research Center (LaRC) has contributed in developing several 2-micron carbon dioxide active remote sensors using the DIAL technique. Currently, an airborne 2-micron triple-pulse integrated path differential absorption (IPDA) lidar is under development at NASA LaRC. This paper focuses on the advancement of the 2-micron triple-pulse IPDA lidar development. Updates on the state-of-the-art triple-pulse laser transmitter will be presented including the status of wavelength control, packaging and lidar integration. In addition, receiver development updates will also be presented, including telescope integration, detection systems and data acquisition electronics. Future plan for IPDA lidar system for ground integration, testing and flight validation will be presented.

Low-intensity pulsed ultrasound stimulation facilitates osteogenic differentiation of human periodontal ligament cells.

Directory of Open Access Journals (Sweden)

Bo Hu

Full Text Available Human periodontal ligament cells (hPDLCs possess stem cell properties, which play a key role in periodontal regeneration. Physical stimulation at appropriate intensities such as low-intensity pulsed ultrasound (LIPUS enhances cell proliferation and osteogenic differentiation of mesechymal stem cells. However, the impacts of LIPUS on osteogenic differentiation of hPDLCs in vitro and its molecular mechanism are unknown. This study was undertaken to investigate the effects of LIPUS on osteogenic differentiation of hPDLCs. HPDLCs were isolated from premolars of adolescents for orthodontic reasons, and exposed to LIPUS at different intensities to determine an optimal LIPUS treatment dosage. Dynamic changes of alkaline phosphatase (ALP activities in the cultured cells and supernatants, and osteocalcin production in the supernatants after treatment were analyzed. Runx2 and integrin β1 mRNA levels were assessed by reverse transcription polymerase chain reaction analysis after LIPUS stimulation. Blocking antibody against integrinβ1 was used to assess the effects of integrinβ1 inhibitor on LIPUS-induced ALP activity, osteocalcin production as well as calcium deposition. Our data showed that LIPUS at the intensity of 90 mW/cm2 with 20 min/day was more effective. The ALP activities in lysates and supernatants of LIPUS-treated cells started to increase at days 3 and 7, respectively, and peaked at day 11. LIPUS treatment significantly augmented the production of osteocalcin after day 5. LIPUS caused a significant increase in the mRNA expression of Runx2 and integrin β1, while a significant decline when the integrinβ1 inhibitor was used. Moreover, ALP activity, osteocalcin production as well as calcium nodules of cells treated with both daily LIPUS stimulation and integrinβ1 antibody were less than those in the LIPUS-treated group. In conclusion, LIPUS promotes osteogenic differentiation of hPDLCs, which is associated with upregulation of Runx2 and

Complexes of technetium with pyrophosphate, etidronate, and medronate

International Nuclear Information System (INIS)

Russell, C.D.; Cash, A.G.

1979-01-01

The reduction of [ 99 Tc]pertechnetate was studied as a function of pH in complexing media of pyrophosphate, methylene diphosphonate (MDP), and ethane-1, hydroxy-1, and 1-diphosphonate (HEDP). Test (sampled d-c) and normal-pulse polarography were used to study the reduction of pertechnetate, and normal-pulse polarography (sweeping in the anodic direction) to study the reoxidation of the products. Below pH 6 TcO 4 - was reduced to Tc(III), which could be reoxidized to Tc(IV). Above pH 10, TcO 4 - was reduced in two steps to Tc(V) and Tc(IV), each of which could be reoxidized to TcO 4 - . Between pH 6 and 10 the results differed according to the ligand present. In pyrophosphate and MDP, TcO 4 - was reduced in two steps to Tc(IV) and Tc(III); Tc(III) could be reoxidized in two steps to Tc(IV) and TcO 4 - . In HEDP, on the other hand, TcO 4 - was reduced in two steps to Tc(V) and Tc(III), and could be reoxidized to Tc(IV) and TcO 4 - . Additional waves were observed; they apparently led to unstable products

Determination of Silver(I by Differential Pulse Voltammetry Using a Glassy Carbon Electrode Modified with Synthesized N-(2-Aminoethyl-4,4'-Bipyridine

Directory of Open Access Journals (Sweden)

Gabriel Lucian Radu

2010-12-01

Full Text Available A new modified glassy carbon electrode (GCE based on a synthesized N-(2-aminoethyl-4,4'-bipyridine (ABP was developed for the determination of Ag(I by differential pulse voltammetry (DPV. ABP was covalently immobilized on GC electrodes surface using 4-nitrobenzendiazonium (4-NBD and glutaraldehyde (GA. The Ag(I ions were preconcentrated by chemical interaction with bipyridine under a negative potential (−0.6 V; then the reduced ions were oxidized by differential pulse voltammetry and a peak was observed at 0.34 V. The calibration curve was linear in the concentration range from 0.05 μM to 1 μM Ag(I with a detection limit of 0.025 μM and RSD = 3.6%, for 0.4 μM Ag(I. The presence of several common ions in more than 125-fold excess had no effect on the determination of Ag(I. The developed sensor was applied to the determination of Ag(I in water samples using a standard addition method.

Differential Hall-sensor Pulsed Eddy Current Probe for the Detection of Wall thinning in an Insulated Stainless Steel Pipe

International Nuclear Information System (INIS)

Park, D. G.; Angani, Chandra S.; Cheong, Y. M.; Kim, C. G.

2010-01-01

The local wall thinning is one of the most important factors to limit the life-extension of large structures, such as the pipe lines in the NPPs. The pipelines are covered with a thermal insulator for low thermal loss. The PEC testing is the promising technological approach to the NDT, and it has been principally developed for the measurement of surface flaws, subsurface flaws and corrosion. In the pulsed eddy current (PEC) technique, the excitation coil is driven by repeated pulses. According to the skin - depth relationship multiple frequency components penetrate to different depths, hence the PEC technique has the potential for bringing up deeper information about the tested sample. Because of the potential advantages of the PEC, prevalent investigations on this technique have been done. In the present study a differential probe which is used in the Pulsed Eddy Current (PEC) system has been fabricated for the detection of wall thinning of insulated pipelines in a nuclear power plant (NPP). This technique can be used as a potential tool to detect the corrosion or the wall thinning of the pipelines without removing the insulation

Research on Zheng Classification Fusing Pulse Parameters in Coronary Heart Disease

Science.gov (United States)

Guo, Rui; Wang, Yi-Qin; Xu, Jin; Yan, Hai-Xia; Yan, Jian-Jun; Li, Fu-Feng; Xu, Zhao-Xia; Xu, Wen-Jie

2013-01-01

This study was conducted to illustrate that nonlinear dynamic variables of Traditional Chinese Medicine (TCM) pulse can improve the performances of TCM Zheng classification models. Pulse recordings of 334 coronary heart disease (CHD) patients and 117 normal subjects were collected in this study. Recurrence quantification analysis (RQA) was employed to acquire nonlinear dynamic variables of pulse. TCM Zheng models in CHD were constructed, and predictions using a novel multilabel learning algorithm based on different datasets were carried out. Datasets were designed as follows: dataset1, TCM inquiry information including inspection information; dataset2, time-domain variables of pulse and dataset1; dataset3, RQA variables of pulse and dataset1; and dataset4, major principal components of RQA variables and dataset1. The performances of the different models for Zheng differentiation were compared. The model for Zheng differentiation based on RQA variables integrated with inquiry information had the best performance, whereas that based only on inquiry had the worst performance. Meanwhile, the model based on time-domain variables of pulse integrated with inquiry fell between the above two. This result showed that RQA variables of pulse can be used to construct models of TCM Zheng and improve the performance of Zheng differentiation models. PMID:23737839

Research on Zheng Classification Fusing Pulse Parameters in Coronary Heart Disease

Directory of Open Access Journals (Sweden)

Rui Guo

2013-01-01

Full Text Available This study was conducted to illustrate that nonlinear dynamic variables of Traditional Chinese Medicine (TCM pulse can improve the performances of TCM Zheng classification models. Pulse recordings of 334 coronary heart disease (CHD patients and 117 normal subjects were collected in this study. Recurrence quantification analysis (RQA was employed to acquire nonlinear dynamic variables of pulse. TCM Zheng models in CHD were constructed, and predictions using a novel multilabel learning algorithm based on different datasets were carried out. Datasets were designed as follows: dataset1, TCM inquiry information including inspection information; dataset2, time-domain variables of pulse and dataset1; dataset3, RQA variables of pulse and dataset1; and dataset4, major principal components of RQA variables and dataset1. The performances of the different models for Zheng differentiation were compared. The model for Zheng differentiation based on RQA variables integrated with inquiry information had the best performance, whereas that based only on inquiry had the worst performance. Meanwhile, the model based on time-domain variables of pulse integrated with inquiry fell between the above two. This result showed that RQA variables of pulse can be used to construct models of TCM Zheng and improve the performance of Zheng differentiation models.

Polarographic behaviour of uranium (VI) in tributyl phosphate organic solutions

International Nuclear Information System (INIS)

Degueldre, C.A.; Meklati, M.

1984-01-01

U(VI) determination by D.C. and differential pulse polarography was studied in the organic solutions derived from tributyl phosphate - diluent extracts (after separation from nitric acid media) along with a selected aprotic solvent (i.e.: propylene carbonate and N,N-dimethylacetamide). Miscibility of the TBP-diluent (e.g. cyclohexane, n-hexane, kerosene, n-dodecane) phase with nitric acid as supporting electrolyte, either by addition or already present in the extract was larger in DMA than in PC. In the DMA organic mixture, U(VI) exhibited a DPP peak due to a one electron step, with Esub(p)=-0.4 V (position connected with H 2 O and HNO 3 concentrations). This peak which was proportionnel to the U(VI) concentration from 5x10 -6 to 10 -3 M can be used to determinate directly hexavalent uranium in the industrial organic extraction phases TBP-diluent. (orig.)

Characterization of an electrochemical mercury sensor using alternating current, cyclic, square wave and differential pulse voltammetry

Energy Technology Data Exchange (ETDEWEB)

Guerreiro, Gabriela V.; Zaitouna, Anita J.; Lai, Rebecca Y., E-mail: rlai2@unl.edu

2014-01-31

Graphical abstract: -- Highlights: •An electrochemical Hg(II) sensor based on T–Hg(II)–T sensing motif was fabricated. •A methylene blue-modified DNA probe was used to fabricate the sensor. •Sensor performance was evaluated using ACV, CV, SWV, and DPV. •The sensor behaves as a “signal-off” sensor in ACV and CV. •The sensor behaves as either a “signal-on” or “signal-off” sensor in SWV and DPV. -- Abstract: Here we report the characterization of an electrochemical mercury (Hg{sup 2+}) sensor constructed with a methylene blue (MB)-modified and thymine-containing linear DNA probe. Similar to the linear probe electrochemical DNA sensor, the resultant sensor behaved as a “signal-off” sensor in alternating current voltammetry and cyclic voltammetry. However, depending on the applied frequency or pulse width, the sensor can behave as either a “signal-off” or “signal-on” sensor in square wave voltammetry (SWV) and differential pulse voltammetry (DPV). In SWV, the sensor showed “signal-on” behavior at low frequencies and “signal-off” behavior at high frequencies. In DPV, the sensor showed “signal-off” behavior at short pulse widths and “signal-on” behavior at long pulse widths. Independent of the sensor interrogation technique, the limit of detection was found to be 10 nM, with a linear dynamic range between 10 nM and 500 nM. In addition, the sensor responded to Hg{sup 2+} rather rapidly; majority of the signal change occurred in <20 min. Overall, the sensor retains all the characteristics of this class of sensors; it is reagentless, reusable, sensitive, specific and selective. This study also highlights the feasibility of using a MB-modified probe for real-time sensing of Hg{sup 2+}, which has not been previously reported. More importantly, the observed “switching” behavior in SWV and DPV is potentially generalizable and should be applicable to most sensors in this class of dynamics-based electrochemical biosensors.

Electronic system for recording proportional counter rare pulses with the pulse shape analysis

International Nuclear Information System (INIS)

Barabanov, I.R.; Gavrin, V.N.; Zakharov, Yu.I.; Tikhonov, A.A.

1984-01-01

The anutomated system for recording proportional counter rare pulses is described. The proportional counters are aimed at identification of 37 Ar and H7 1 Gr decays in chemical radiation detectors of solar neutrino. Pulse shape recording by means of a storage oscilloscope and a TV display is performed in the system considered besides two-parametric selection of events (measurement of pulse amplitude in a slow channel and the amplitude of pulse differentiated with time constant of about 10 ns in a parallel fast channel). Pulse discrimination by a front rise rate provides background decrease in the 55 Fe range (5.9 keV) by 6 times; the visual analysis of pulse shapes recorded allows to decrease the background additionally by 25-30%. The background counting rate in the 55 Fe range being equal to 1 pulse per 1.5 days, is obtained when using the installation described above, as well as the passive Pb shield 5 cm thick, and the active shield based on the anticoincidence NaI(Tl) detector with the cathode 5.6 mm in-diameter made of Fe fabircated by zone melting. The installation described allows to reach the background level of 0.6 pulse/day (the total coefficient of background attenuation is 400). Further background decrease is supposed to be provided by installation allocation in the low-noise underground laboratory of the Baksan Neutrino Observatory

Determination of antioxidant activity of spices and their active principles by differential pulse voltammetry.

Science.gov (United States)

Palma, Alberto; Ruiz Montoya, Mercedes; Arteaga, Jesús F; Rodríguez Mellado, Jose M

2014-01-22

The anodic oxidation of mercury in the presence of hydrogen peroxide in differential pulse voltammetry (DPV) was used to determine the antioxidant (AO) character of radical scavengers. Hydroperoxide radical is formed at the potentials of the oxidation peak on mercury electrodes, such radical reacting with the antioxidants in different extension. The parameter C10 (antioxidant concentration at which the peak area decreases by 10%) is used to measure the scavenging activity of the individual antioxidants. To establish the scavenging activity of antioxidant mixtures as a whole, the parameter, μ10 as the reverse of V10, V10 being the volume necessary to decrease the peak area in DPV by 10%, was selected. Higher μ10 values correspond to higher scavenging activity. The studies have been extended to aqueous extracts of some species. The results may be useful in explaining the effect of spices in vitro and in vivo studies.

Age-related change in renal corticomedullary differentiation: evaluation with noncontrast-enhanced steady-state free precession (SSFP) MRI with spatially selective inversion pulse using variable inversion time.

Science.gov (United States)

Noda, Yasufumi; Kanki, Akihiko; Yamamoto, Akira; Higashi, Hiroki; Tanimoto, Daigo; Sato, Tomohiro; Higaki, Atsushi; Tamada, Tsutomu; Ito, Katsuyoshi

2014-07-01

To evaluate age-related change in renal corticomedullary differentiation and renal cortical thickness by means of noncontrast-enhanced steady-state free precession (SSFP) magnetic resonance imaging (MRI) with spatially selective inversion recovery (IR) pulse. The Institutional Review Board of our hospital approved this retrospective study and patient informed consent was waived. This study included 48 patients without renal diseases who underwent noncontrast-enhanced SSFP MRI with spatially selective IR pulse using variable inversion times (TIs) (700-1500 msec). The signal intensity of renal cortex and medulla were measured to calculate renal corticomedullary contrast ratio. Additionally, renal cortical thickness was measured. The renal corticomedullary junction was clearly depicted in all patients. The mean cortical thickness was 3.9 ± 0.83 mm. The mean corticomedullary contrast ratio was 4.7 ± 1.4. There was a negative correlation between optimal TI for the best visualization of renal corticomedullary differentiation and age (r = -0.378; P = 0.001). However, there was no significant correlation between renal corticomedullary contrast ratio and age (r = 0.187; P = 0.20). Similarly, no significant correlation was observed between renal cortical thickness and age (r = 0.054; P = 0.712). In the normal kidney, noncontrast-enhanced SSFP MRI with spatially selective IR pulse can be used to assess renal corticomedullary differentiation and cortical thickness without the influence of aging, although optimal TI values for the best visualization of renal corticomedullary junction were shortened with aging. © 2013 Wiley Periodicals, Inc.

Quenching H2 autoionization interferences with ultrashort xuv laser pulses

International Nuclear Information System (INIS)

González-Castrillo, Alberto; Palacios, Alicia; Martín, Fernando; Bachau, Henri

2012-01-01

In contrast with atomic photoionization or molecular direct photoionization, in the autoionization region, electron and proton kinetic-energy differential probabilities resulting from a short pulse cannot be reconstructed by the incoherent superposition of those resulting from long pulses.

Synergistic effect of defined artificial extracellular matrices and pulsed electric fields on osteogenic differentiation of human MSCs.

Science.gov (United States)

Hess, Ricarda; Jaeschke, Anna; Neubert, Holger; Hintze, Vera; Moeller, Stephanie; Schnabelrauch, Matthias; Wiesmann, Hans-Peter; Hart, David A; Scharnweber, Dieter

2012-12-01

In vivo, bone formation is a complex, tightly regulated process, influenced by multiple biochemical and physical factors. To develop a vital bone tissue engineering construct, all of these individual components have to be considered and integrated to gain an in vivo-like stimulation of target cells. The purpose of the present studies was to investigate the synergistic role of defined biochemical and physical microenvironments with respect to osteogenic differentiation of human mesenchymal stem cells (MSCs). Biochemical microenvironments have been designed using artificial extracellular matrices (aECMs), containing collagen I (coll) and glycosaminoglycans (GAGs) like chondroitin sulfate (CS), or a high-sulfated hyaluronan derivative (sHya), formulated as coatings on three-dimensional poly(caprolactone-co-lactide) (PCL) scaffolds. As part of the physical microenvironment, cells were exposed to pulsed electric fields via transformer-like coupling (TC). Results showed that aECM containing sHya enhanced osteogenic differentiation represented by increases in ALP activity and gene-expression (RT-qPCR) of several bone-related proteins (RUNX-2, ALP, OPN). Electric field stimulation alone did not influence cell proliferation, but osteogenic differentiation was enhanced if osteogenic supplements were provided, showing synergistic effects by the combination of sHya and electric fields. These results will improve the understanding of bone regeneration processes and support the development of effective tissue engineered bone constructs. Copyright © 2012 Elsevier Ltd. All rights reserved.

A single chip pulse processor for nuclear spectroscopy

International Nuclear Information System (INIS)

Hilsenrath, F.; Bakke, J.C.; Voss, H.D.

1985-01-01

A high performance digital pulse processor, integrated into a single gate array microcircuit, has been developed for spaceflight applications. The new approach takes advantage of the latest CMOS high speed A/D flash converters and low-power gated logic arrays. The pulse processor measures pulse height, pulse area and the required timing information (e.g. multi detector coincidence and pulse pile-up detection). The pulse processor features high throughput rate (e.g. 0.5 Mhz for 2 usec gausssian pulses) and improved differential linearity (e.g. + or - 0.2 LSB for a + or - 1 LSB A/D). Because of the parallel digital architecture of the device, the interface is microprocessor bus compatible. A satellite flight application of this module is presented for use in the X-ray imager and high energy particle spectrometers of the PEM experiment on the Upper Atmospheric Research Satellite

Basic chemistry for radioactive waste management

International Nuclear Information System (INIS)

Park, Kyong Kyun; Kim, Won Ho; Jee, Kwang Yong; Kim, Jong Goo; Park, Yeong Jae; Yu, Mahn Su; Jee, Choun Suk; Song, Byoung Chul; Choi, Ke Chon; Eom, Tae Yoon

1991-03-01

The complex formation between uranium(VI) ion and chloride ion in aqueous solution can be confirmed by UV-Vis absorption spectroscopy and differential pulse polarography. Absorption spectra and differential pulse polarograms of uranyl ion in hypochlorite/chloride media shows for its interaction with hypochlorite ion. Although the spectral changes for its interaction are ambiguous, new half-wave potential due to the interaction of uranium(VI)-hypochlorite ion appears in the differential pulse polarogram. Kinetic studies on the electron transfer reaction between U(IV) ion and Fe(III)(phen)3 complex in the solution containing dipicolinic acid or phosphoric acid show that the reaction rate slows down in low ligands concentration and speeds up in high ligands concentration. This result indicates that free functional group of multidentate ligands coordinated to U(IV) ion interacts at the 2 or 9 position carbon atom of phenanthroline ring in iron(III) complex. The presence of 5-sulfosalicylic acid slows down the electron transfer reaction between U(IV) ion and Fe(III) ion through the complex formation with two reactants. More information about the complex formation between U(IV) ion and 5-sulfosalicylic acid is needed for accurate explanation of the reaction mechanism. Both plutonium and uranium are extracted by TBP/dodecane from the aqueous solution, in which the post-irradiated nuclear fuel pellet is dissolved. They are back-extracted into 2M HCl solution after reducing plutonium(IV) ion to plutonium(III) ion by added U(IV) ion. Removing uranium on the DOWEX A-l anion exchange column, plutonium is eluted later for its purification. Gamma and alpha spectroscopic measurements shows the high decontamination factor and 95% recovery for the initial amounts of plutonium. (Author)

Zinc (Zn Analysis in Milk by Microwave Oven Digestion and Differential Pulse Anodic Stripping Voltametry (DPASV Technique

Directory of Open Access Journals (Sweden)

Mohineesh

2013-04-01

Full Text Available Milk is very important component of human diet. The presence of over limit of heavy metal in milk may create significant health problems. In the present study, the direct determination of Zinc (Zn heavy metal in milk samples of different brands was carried out by differential pulse anodic stripping Voltammetric technique at Hanging Mercury Drop Electrode (HMDE. Milk samples were processed by microwave oven digestion using HP/VHP Vessels and TFM Liners and nitric acid (HNO3.Determination of Zn was made in acetate buffer (pH 4.6 with a sweep rate (scan rate of 59.5 mV/s and pulse amplitude 50mV by HMDE by standard addition method. The solution was stirred during pre-electrolysis at -1150mV (vs. Ag/AgCl for 90 seconds and the potential was scanned from -1150V to +100V (vs. Ag/AgCl. The zinc ions were deposited by reduction at -1150 mV on HMDE. The stripping current arising from the oxidation of metal was correlated with the concentration the metal in the sample. .As a result the minimum level of Zn observed in the milk sample of different brands was determined as 2.28 mgL−1.

Differential pulse amplitude modulation for multiple-input single-output OWVLC

Science.gov (United States)

Yang, S. H.; Kwon, D. H.; Kim, S. J.; Son, Y. H.; Han, S. K.

2015-01-01

White light-emitting diodes (LEDs) are widely used for lighting due to their energy efficiency, eco-friendly, and small size than previously light sources such as incandescent, fluorescent bulbs and so on. Optical wireless visible light communication (OWVLC) based on LED merges lighting and communications in applications such as indoor lighting, traffic signals, vehicles, and underwater communications because LED can be easily modulated. However, physical bandwidth of LED is limited about several MHz by slow time constant of the phosphor and characteristics of device. Therefore, using the simplest modulation format which is non-return-zero on-off-keying (NRZ-OOK), the data rate reaches only to dozens Mbit/s. Thus, to improve the transmission capacity, optical filtering and pre-, post-equalizer are adapted. Also, high-speed wireless connectivity is implemented using spectrally efficient modulation methods: orthogonal frequency division multiplexing (OFDM) or discrete multi-tone (DMT). However, these modulation methods need additional digital signal processing such as FFT and IFFT, thus complexity of transmitter and receiver is increasing. To reduce the complexity of transmitter and receiver, we proposed a novel modulation scheme which is named differential pulse amplitude modulation. The proposed modulation scheme transmits different NRZ-OOK signals with same amplitude and unit time delay using each LED chip, respectively. The `N' parallel signals from LEDs are overlapped and directly detected at optical receiver. Received signal is demodulated by power difference between unit time slots. The proposed scheme can overcome the bandwidth limitation of LEDs and data rate can be improved according to number of LEDs without complex digital signal processing.

Seasonal and spatial distributions of tributyltin in surface sediment of the Tolka Estuary, Dublin, Ireland

Energy Technology Data Exchange (ETDEWEB)

Buggy, Conor J. [Department of Biotechnology, Dublin City University, Glasnevin, Dublin (Ireland); Tobin, John M. [Department of Biotechnology, Dublin City University, Glasnevin, Dublin (Ireland)]. E-mail: john.tobin@dcu.ie

2006-09-15

Aquatic pollution by tributyltin (TBT) is of concern because of its high toxicity to marine life. TBT loadings of estuarine sediments may remain elevated because of long flushing times in estuaries due to their enclosed physicality. The Tolka Estuary, Co. Dublin, Ireland, is a typical Irish urban estuary. It has a significant pollution loading. The results of 12 months' analysis of TBT spatial and temporal distributions in this estuary are presented in this paper. Data from a total of 10 sample points are presented. The concentrations of TBT in the sediment were analysed using differential pulse polarography. Significant seasonal and spatial trends in TBT distribution were observed over the 12-month period. TBT concentrations ranged from 0.1 ppb in winter to 8.6 ppb in summer with a 1.5 ppb average. Organic matter (OM) concentrations of sediment exhibited similar seasonal trends and a positive correlation between OM and TBT distributions was observed. - TBT concentrations varied with seasons and correlated well with organic matter.

Seasonal and spatial distribution of metals in surface sediment of an urban estuary

International Nuclear Information System (INIS)

Buggy, Conor J.; Tobin, John M.

2008-01-01

Aquatic pollution by metals is of concern because of various toxic effects to marine life. The Tolka Estuary, Co. Dublin, Ireland, is a typical Irish urban estuary. It has a significant metal loading originating from the urban environment. Results of a 25 month analysis of cadmium, copper, lead and zinc spatial and temporal distribution over 10 sample locations in this estuary are presented in this paper. Metal concentrations were analysed using differential pulse polarography. Significant seasonal and spatial trends in metal distribution were observed over the 25 months. Sediment metal concentrations gradually increased (30-120%) in spring to a maximum at the end of summer which was followed by a decrease in winter months (30-60%). Sediment organic matter (OM) concentrations exhibited similar seasonal trends and a positive correlation between OM and metal distributions was observed, implying OM had an influence on metal distributions over time. - Assessment and correlation of the seasonal and spatial distribution of metals and organic matter in surface sediment of an urban estuary

Seasonal and spatial distributions of tributyltin in surface sediment of the Tolka Estuary, Dublin, Ireland

International Nuclear Information System (INIS)

Buggy, Conor J.; Tobin, John M.

2006-01-01

Aquatic pollution by tributyltin (TBT) is of concern because of its high toxicity to marine life. TBT loadings of estuarine sediments may remain elevated because of long flushing times in estuaries due to their enclosed physicality. The Tolka Estuary, Co. Dublin, Ireland, is a typical Irish urban estuary. It has a significant pollution loading. The results of 12 months' analysis of TBT spatial and temporal distributions in this estuary are presented in this paper. Data from a total of 10 sample points are presented. The concentrations of TBT in the sediment were analysed using differential pulse polarography. Significant seasonal and spatial trends in TBT distribution were observed over the 12-month period. TBT concentrations ranged from 0.1 ppb in winter to 8.6 ppb in summer with a 1.5 ppb average. Organic matter (OM) concentrations of sediment exhibited similar seasonal trends and a positive correlation between OM and TBT distributions was observed. - TBT concentrations varied with seasons and correlated well with organic matter

Application of Box-Behnken designs in parameters optimization of differential pulse anodic stripping voltammetry for lead(II) determination in two electrolytes.

Science.gov (United States)

Yu, Xiao-Lan; He, Yong

2017-06-05

Box-Behnken design was advantageous to parameters optimization of differential pulse anodic stripping voltammetry (DPASV) for the analysis of lead(II) with its high efficiency and accuracy. Five Box-Behnken designs were designed and conducted in the electrolyte of 0.1 mol/L acetate buffer and 0.1 mol/L HCl without the removal of oxygen. Significant parameters and interactions in each electrolyte were found (P-value Box-Behnken designs in parameters optimization of DPASV for lead(II) determination regardless of the electrolyte kinds.

Self-compression of intense short laser pulses in relativistic magnetized plasma

Energy Technology Data Exchange (ETDEWEB)

Olumi, M.; Maraghechi, B., E-mail: behrouz@aut.ac.ir [Department of Physics, Amirkabir University of Technology, Post code 15916-34311 Tehran (Iran, Islamic Republic of)

2014-11-15

The compression of a relativistic Gaussian laser pulse in a magnetized plasma is investigated. By considering relativistic nonlinearity and using non-linear Schrödinger equation with paraxial approximation, a second-order differential equation is obtained for the pulse width parameter (in time) to demonstrate the longitudinal pulse compression. The compression of laser pulse in a magnetized plasma can be observed by the numerical solution of the equation for the pulse width parameter. The effects of magnetic field and chirping are investigated. It is shown that in the presence of magnetic field and negative initial chirp, compression of pulse is significantly enhanced.

Differential-phase-shift quantum key distribution using coherent light

International Nuclear Information System (INIS)

Inoue, K.; Waks, E.; Yamamoto, Y.

2003-01-01

Differential-phase-shift quantum key distribution based on two nonorthogonal states is described. A weak coherent pulse train is sent from Alice to Bob, in which the phase of each pulse is randomly modulated by {0,π}. Bob measures the differential phase by a one-bit delay circuit. The system has a simple configuration without the need for an interferometer and a bright reference pulse in Alice's site, unlike the conventional QKD system based on two nonorthogonal states, and has an advantage of improved communication efficiency. The principle of the operation is successfully demonstrated in experiments

Trace analysis of lead and cadmium in seafoods by differential pulse anodic stripping voltametry

International Nuclear Information System (INIS)

Sumera, F.C.; Verceluz, F.P.; Kapauan, P.A.

1979-01-01

A method for the simultaneous determination of cadmium and lead in seafoods is described. The sample is dry ashed in a muffle furnace elevating the temperature gradually up to 500 0 C. The ashed sample is treated with concentrated nitric acid, dried on a heating plate and returned to the muffle furnace for further heating. The treated ash is then dissolved in 1 N HCL acetate buffer and citric acid are added and the pH adjusted to 3.6-4. The resulting solution is analyzed for lead and cadmium by differential pulse anodic stripping voltametry (DPASV) using a wax-impregnated graphite thin film electrode. The average recoveries of 0.4 of cadmium and lead added to 5 fish samples were 97% and 99% respectively. The standard deviations, on a homogenized shark sample for lead and cadmium analysis were 6.7 ppb and 12.3 ppb, respectively, and the relative standard deviations were 21.0% and 15.5% respectively. Studies on instrumental parameters involved in the DPASV step of analysis and methods of measuring peak current signals were also made. (author)

Development of an Airborne Triple-Pulse 2-Micron Integrated Path Differential Absorption Lidar (IPDA) for Simultaneous Airborne Column Measurements of Carbon Dioxide and Water Vapor in the Atmosphere

Science.gov (United States)

Singh, Upendra N.; Petros, Mulugeta; Refaat, Tamer F.; Yu, Jirong; Antill, Charles W.; Remus, Ruben

2016-01-01

This presentation will provide status and details of an airborne 2-micron triple-pulse integrated path differential absorption (IPDA) lidar being developed at NASA Langley Research Center with support from NASA ESTO Instrument Incubator Program. The development of this active optical remote sensing IPDA instrument is targeted for measuring both atmospheric carbon dioxide and water vapor in the atmosphere from an airborne platform. This presentation will focus on the advancement of the 2-micron triple-pulse IPDA lidar development. Updates on the state-of-the-art triple-pulse laser transmitter will be presented including the status of seed laser locking, wavelength control, receiver and detector upgrades, laser packaging and lidar integration. Future plan for IPDA lidar system for ground integration, testing and flight validation will also be presented.

The contents of sesamol and related lignans in sesame, tahina and halva as determined by a newly developed polarographic and stripping voltammetric analysis

Energy Technology Data Exchange (ETDEWEB)

Tokusoglu, O.; Kocak, S.; Aycan, S.

2009-07-01

The contents of antioxidant lignans (Sesamol) in sesame, commercial formulations of tahina and halva, which are processed tahina foods, were determined by Differential Pulse Polarography (DPP) with a capillary hanging mercury drop electrode (HMDE). A platinum wire was used as the counter electrode and Ag/AgCl was the reference electrode. Samples have been analyzed by standard addition procedures and found to be quantitative (p<0.01). Due to the fact that sesamol is an oil-soluble phenolic compound , it was found in the oil levels of sesame, tahina and halvas. Sesame samples contained 51.05-56.46 % in oil whereas tahina samples contained 52.12-53.79 % in oil. The oil percentage of plain halva was found to be 28.79 - 30.13 % (p<0.01). Phenolic lignans sesamol in sesame was 0.26-0.32 mg/100g oil, whereas the sesamol in tahina was 10.98-12.33 mg/100g oil. The sesamol in commercial plain halva samples and the open marketed plain halva samples contained 8.24-9.12 mg/100g oil and 4.97 mg sesamol /100g oil, respectively (R{sup 2}=0.9999) (p<0.01). The proposed Differential Pulse Polarographic (DPP) method is a rapid, reproducible procedure for the simultaneous determination of phenolic lignans in sesame and food products with sesame. It provides an adequate, sensitive, quantitative detection of these nutraceuticals in the commercial food industry. (Author) 26 refs.

Polarographic study of acrolein and its determination by flow injection with amperometric detection at a mercury electrode.

Science.gov (United States)

Naranjo Rodríguez, I; Muñoz Leyva, J A; Hidalgo Hidalgo de Cisneros, J L

1996-07-01

A study of the electrochemical behavior of acrolein at a dropping mercury electrode using different polarographic techniques is described. Theoretical studies of the reversibility of the wave of acrolein were carried out using two different polarographic techniques: direct current tast and differential pulse. Differential pulse polarography may be used to determine acrolein concentration in a Britton-Robinson buffer solution of pH 10 in the ranges 2 x 10(-7)10(-8) and 5 x 10(-8)-10(-4) mol dm(-3) and a coefficient of variation of 1.7% for a concentration of 10(-5)mol dm(-3). A flow injection method with amperometric detection at a potential of -1.4V using a mercury electrode is also described. Before each injection, any drop hanging from the tip of the capillary needs to be dislodged and a new electrode drop dispensed; three different drop sizes were tested. A linear relationship between peak intensity and acrolein concentration was obtained in the range 10(-5)-10(-7) mol dm(-3), with a detection limit of 9.8 x 10(-8) mol dm(-) 3 and a coefficient of variation of 2.9% for a 2 x 10(-7) mol dm(-3) concentration. Several organic and inorganic species were tested in order to ascertain whether they interfered with the signal for acrolein. The proposed methods were applied to the determination of acrolein in seawater samples.

Contribution to time resolved X-ray fluence and differential spectra measurement method improvement in 5-200 KeV range. Application to pulsed emission sources

International Nuclear Information System (INIS)

Vie, M.

1983-09-01

Two types of sensors have been developed to measure locally the time-resolved fluence and differential energetic spectrum of pulsed X-ray in the energy range 5 to 200 keV. Rise time of these sensors is very short (10 ns) in order to permit time-resolved measurements. Fluence sensors have been developed by putting filters in front of detector in order to make sensor response independent of X-ray energy and proportional to X-ray fluence. The energetic differential spectrum was calculated by way of a method similar to the ROSS method but using filters separated within a pair defining adjacent spectral width. A detailed analysis of uncertainties affecting calculated fluence and spectrum has been done [fr

A study of new pulse auscultation system.

Science.gov (United States)

Chen, Ying-Yun; Chang, Rong-Seng

2015-04-14

This study presents a new type of pulse auscultation system, which uses a condenser microphone to measure pulse sound waves on the wrist, captures the microphone signal for filtering, amplifies the useful signal and outputs it to an oscilloscope in analog form for waveform display and storage and delivers it to a computer to perform a Fast Fourier Transform (FFT) and convert the pulse sound waveform into a heartbeat frequency. Furthermore, it also uses an audio signal amplifier to deliver the pulse sound by speaker. The study observed the principles of Traditional Chinese Medicine's pulsing techniques, where pulse signals at places called "cun", "guan" and "chi" of the left hand were measured during lifting (100 g), searching (125 g) and pressing (150 g) actions. Because the system collects the vibration sound caused by the pulse, the sensor itself is not affected by the applied pressure, unlike current pulse piezoelectric sensing instruments, therefore, under any kind of pulsing pressure, it displays pulse changes and waveforms with the same accuracy. We provide an acquired pulse and waveform signal suitable for Chinese Medicine practitioners' objective pulse diagnosis, thus providing a scientific basis for this Traditional Chinese Medicine practice. This study also presents a novel circuit design using an active filtering method. An operational amplifier with its differential features eliminates the interference from external signals, including the instant high-frequency noise. In addition, the system has the advantages of simple circuitry, cheap cost and high precision.

Pulse height model for deuterated scintillation detectors

International Nuclear Information System (INIS)

Wang, Haitang; Enqvist, Andreas

2015-01-01

An analytical model of light pulse height distribution for finite deuterated scintillation detectors is created using the impulse approximation. Particularly, the energy distribution of a scattered neutron is calculated based on an existing collision probability scheme for general cylindrical shaped detectors considering double differential cross-sections. The light pulse height distribution is analytically and numerically calculated by convoluting collision sequences with the light output function for an EJ-315 detector from our measurements completed at Ohio University. The model provides a good description of collision histories capturing transferred neutron energy in deuterium-based scintillation materials. The resulting light pulse height distribution details pulse compositions and their corresponding contributions. It shows that probabilities of neutron collision with carbon and deuterium nuclei are comparable, however the light pulse amplitude due to collisions with carbon nuclei is small and mainly located at the lower region of the light pulse distribution axis. The model can explore those neutron interaction events that generate pulses near or below a threshold that would be imposed in measurements. A comparison is made between the light pulse height distributions given by the analytical model and measurements. It reveals a significant probability of a neutron generating a small light pulse due to collisions with carbon nuclei when compared to larger light pulse generated by collisions involving deuterium nuclei. This model is beneficial to understand responses of scintillation materials and pulse compositions, as well as nuclei information extraction from recorded pulses.

Computer-Aided Video Differential Planimetry

Science.gov (United States)

Tobin, Michael; Djoleto, Ben D.

1984-08-01

THE VIDEO DIFFERENTIAL PLANIMETER (VDP)1 is a re-mote sensing instrument that can measure minute changes in the area of any object seen by an optical scanning system. The composite video waveforms obtained by scanning the object against a contrasting back-ground are amplified and shaped to yield a sequence of constant amplitude pulses whose polarity distinguishes the studied area from its background and whose varying widths reflect the dynamics of the viewed object. These pulses are passed through a relatively long time-constant capacitor-resistor circuit and are then fed into an integrator. The net integration voltage resulting from the most recent sequence of object-background time pulses is recorded and the integrator is returned to zero at the end of each video frame. If the object's area remains constant throughout the following frame, the integrator's summation will also remain constant. However, if the object's area varies, the positive and negative time pulses entering the integrator will change, and the integrator's summation will vary proportionately. The addition of a computer interface and a video recorder enhances the versatility and the resolving power of the VDP by permitting the repeated study and analysis of selected portions of the recorded data, thereby uncovering the major sources of the object's dynamics. Among the medical and biological procedures for which COMPUTER-AIDED VIDEO DIFFERENTIAL PLANIMETRY is suitable are Ophthalmoscopy, Endoscopy, Microscopy, Plethysmography, etc. A recent research study in Ophthalmoscopy2 will be cited to suggest a useful application of Video Differential Planimetry.

Hydroxyapatite thin films grown by pulsed laser deposition and matrix assisted pulsed laser evaporation: Comparative study

Science.gov (United States)

Popescu-Pelin, G.; Sima, F.; Sima, L. E.; Mihailescu, C. N.; Luculescu, C.; Iordache, I.; Socol, M.; Socol, G.; Mihailescu, I. N.

2017-10-01

Pulsed Laser Deposition (PLD) and Matrix Assisted Pulsed Laser Evaporation (MAPLE) techniques were applied for growing hydroxyapatite (HA) thin films on titanium substrates. All experiments were conducted in a reaction chamber using a KrF* excimer laser source (λ = 248 nm, τFWHM ≈ 25 ns). Half of the samples were post-deposition thermally treated at 500 °C in a flux of water vapours in order to restore crystallinity and improve adherence. Coating surface morphologies and topographies specific to the deposition method were evidenced by scanning electron, atomic force microscopy investigations and profilometry. They were shown to depend on deposition technique and also on the post-deposition treatment. Crystalline structure of the coatings evaluated by X-ray diffraction was improved after thermal treatment. Biocompatibility of coatings, cellular adhesion, proliferation and differentiation tests were conducted using human mesenchymal stem cells (MSCs). Results showed that annealed MAPLE deposited HA coatings were supporting MSCs proliferation, while annealed PLD obtained films were stimulating osteogenic differentiation.

Study of antioxidant properties of a water-soluble Vitamin E derivative-tocopherol monoglucoside (TMG) by differential pulse voltammetry.

Science.gov (United States)

Korotkova, E I; Avramchik, O A; Kagiya, T V; Karbainov, Y A; Tcherdyntseva, N V

2004-06-17

Study of antioxidant properties of tocopherol monoglucoside (TMG), a water-soluble Vitamin E derivative, by differential pulse voltammetry has been carried out in this work. The pH influence on the antioxidant properties of TMG has been also investigated. It was observed that the antioxidant activity of TMG is greater at 6.90TMG and reactive oxygen species have been considered. Antioxidant activity of some standard antioxidants including Vitamin E was given for comparison. The results indicate that the TMG is an effective antioxidant in neutral solutions. The oxidation potential for TMG at pH 7.31 has been found (E=0.55+/-0.03V versus Ag|AgCl|KCl(sat) electrode). Finally the use of TMG for protection against oxidative stress has been recommended.

Differential pulse voltammetric determination of salbutamol sulfate in syrup pharmaceutical formulation using poly(4-amino-3-hydroxynaphthalene sulfonic acid modified glassy carbon electrode

Directory of Open Access Journals (Sweden)

Meareg Amare

2017-10-01

Full Text Available A new method for determination of salbutamol sulfate has been developed using poly(4-amino-3-hydroxynaphthalene sulfonic acid/GCE. Cyclic voltammetric investigation of the electrochemical behavior of salbutamol sulfate at the polymer modified glassy carbon unveiled electrocatalytic activity of the modifier towards irreversible oxidation of salbutamol sulfate. Dependence of peak current predominantly on scan rate than on square root of scan rate, and peak potential shift with pH demonstrated that oxidation of salbutamol sulfate at the polymer modified electrode follows adsorption reaction kinetics with proton participation.Under optimized solution and differential pulse voltammetric parameters, the oxidative peak current showed linear dependence on salbutamol sulfate concentration in the range 0.2 to 8 μM with method detection limit (3s/m and determination coefficient (R2 of 6.8 × 10−8 M and 0.99786, respectively. Low method detection limit, relatively wide linear range, and recovery results of spiked standard salbutamol sulfate in syrup samples in the range 96.7–98.9% validated the method for determination of salbutamol sulfate in pharmaceutical formulations.Differential pulse voltammetric analysis of salbutamol sulfate syrup formulation for its salbutamol sulfate content revealed 98.8 to 99.3% of the labeled value confirming the applicability of the developed method for determination of salbutamol sulfate in real samples. Keywords: Electrochemistry, Analytical chemistry

Essential and trace elements in differential pulses, spices and vegetables

International Nuclear Information System (INIS)

Chowdhury, M.Z.A.

2004-01-01

The amounts of bio-chemically important elements for human bodies such as Na, K, Ca, P, Mg, Fe and Cu in some widely used pulses and spices in Chittagong were determined by using flame photometry and UV-Visible spectrophotometry. Similarly, the amounts of Mg, Fe and Cu in some leafy and non-leafy vegetable in Chittagong were determined by the UV-Visible spectrophotometric method. The essential elements such as Na, K, Ca and P were found in mg/kg levels. The amounts of trace metal such as Mg, Fe and Cu in pulses and species were just within the range of human necessity. However, the amounts of Mg, Fe and Cu in leafy and non-leafy vegetables were so negligible that they can not be considered as adequate for health, except their food-values constituted by the higher contents of starch. (author)

Supervised learning methods for pathological arterial pulse wave differentiation: A SVM and neural networks approach.

Science.gov (United States)

Paiva, Joana S; Cardoso, João; Pereira, Tânia

2018-01-01

The main goal of this study was to develop an automatic method based on supervised learning methods, able to distinguish healthy from pathologic arterial pulse wave (APW), and those two from noisy waveforms (non-relevant segments of the signal), from the data acquired during a clinical examination with a novel optical system. The APW dataset analysed was composed by signals acquired in a clinical environment from a total of 213 subjects, including healthy volunteers and non-healthy patients. The signals were parameterised by means of 39pulse features: morphologic, time domain statistics, cross-correlation features, wavelet features. Multiclass Support Vector Machine Recursive Feature Elimination (SVM RFE) method was used to select the most relevant features. A comparative study was performed in order to evaluate the performance of the two classifiers: Support Vector Machine (SVM) and Artificial Neural Network (ANN). SVM achieved a statistically significant better performance for this problem with an average accuracy of 0.9917±0.0024 and a F-Measure of 0.9925±0.0019, in comparison with ANN, which reached the values of 0.9847±0.0032 and 0.9852±0.0031 for Accuracy and F-Measure, respectively. A significant difference was observed between the performances obtained with SVM classifier using a different number of features from the original set available. The comparison between SVM and NN allowed reassert the higher performance of SVM. The results obtained in this study showed the potential of the proposed method to differentiate those three important signal outcomes (healthy, pathologic and noise) and to reduce bias associated with clinical diagnosis of cardiovascular disease using APW. Copyright © 2017 Elsevier B.V. All rights reserved.

Electroperturbation of human stratum corneum fine structure by high voltage pulses: a freeze-fracture electron microscopy and differential thermal analysis study.

Science.gov (United States)

Jadoul, A; Tanojo, H; Préat, V; Bouwstra, J A; Spies, F; Boddé, H E

1998-08-01

Application of high voltage pulses (HVP) to the skin has been shown to promote the transdermal drug delivery by a mechanism involving skin electroporation. The aim of this study was to detect potential changes in lipid phase and ultrastructure induced in human stratum corneum by various HVP protocols, using differential thermal analysis and freeze-fracture electron microscopy. Due to the time involved between the moment the electric field is switched off and the analysis, only "secondary" phenomena rather than primary events could be observed. A decrease in enthalpies for the phase transitions observed at 70 degrees C and 85 degrees C was detected by differential thermal analysis after HVP treatment. No changes in transition temperature could be seen. The freeze-fracture electron microscopy study revealed a dramatic perturbation of the lamellar ordering of the intercellular lipid after application of HVP. Most of the planes displayed rough surfaces. The lipid lamellae exhibited rounded off steps or a vanished stepwise order. There was no evidence for perturbation of the corneocytes content. In conclusion, the freeze-fracture electron microscopy and differential thermal analysis studies suggest that HVP application induces a general perturbation of the stratum corneum lipid ultrastructure.

Determination of transport and reaction swarm coefficients from the analysis of complex transient pulses from the pulsed Townsend experiment

International Nuclear Information System (INIS)

Bekstein, A; De Urquijo, J; Rodríguez-Luna, J C; Juárez, A M; Ducasse, O

2012-01-01

We present in this paper the interpretation and analysis of transient pulses from a pulsed Townsend experiment by solving the continuity equations of the charged carriers (electrons and ions) involved in the avalanche. The set of second order partial differential equations is solved by SIMAV, a simulator designed specifically for the pulsed Townsend avalanche. Complex situations involving processes such as electron detachment, ion-molecule reactions, Penning ionization and secondary electron emission from ion impact at the cathode, virtually impossible to solve analytically, are discussed here to illustrate the capability of the simulator to help explain the various reaction processes involved in the avalanche, and also to derive some of the transport and reaction coefficients.

A Study of New Pulse Auscultation System

Directory of Open Access Journals (Sweden)

Ying-Yun Chen

2015-04-01

Full Text Available This study presents a new type of pulse auscultation system, which uses a condenser microphone to measure pulse sound waves on the wrist, captures the microphone signal for filtering, amplifies the useful signal and outputs it to an oscilloscope in analog form for waveform display and storage and delivers it to a computer to perform a Fast Fourier Transform (FFT and convert the pulse sound waveform into a heartbeat frequency. Furthermore, it also uses an audio signal amplifier to deliver the pulse sound by speaker. The study observed the principles of Traditional Chinese Medicine’s pulsing techniques, where pulse signals at places called “cun”, “guan” and “chi” of the left hand were measured during lifting (100 g, searching (125 g and pressing (150 g actions. Because the system collects the vibration sound caused by the pulse, the sensor itself is not affected by the applied pressure, unlike current pulse piezoelectric sensing instruments, therefore, under any kind of pulsing pressure, it displays pulse changes and waveforms with the same accuracy. We provide an acquired pulse and waveform signal suitable for Chinese Medicine practitioners’ objective pulse diagnosis, thus providing a scientific basis for this Traditional Chinese Medicine practice. This study also presents a novel circuit design using an active filtering method. An operational amplifier with its differential features eliminates the interference from external signals, including the instant high-frequency noise. In addition, the system has the advantages of simple circuitry, cheap cost and high precision.

Spatiotemporal optical pulse transformation by a resonant diffraction grating

Energy Technology Data Exchange (ETDEWEB)

Golovastikov, N. V.; Bykov, D. A., E-mail: bykovd@gmail.com; Doskolovich, L. L., E-mail: leonid@smr.ru; Soifer, V. A. [Russian Academy of Sciences, Image Processing Systems Institute (Russian Federation)

2015-11-15

The diffraction of a spatiotemporal optical pulse by a resonant diffraction grating is considered. The pulse diffraction is described in terms of the signal (the spatiotemporal incident pulse envelope) passage through a linear system. An analytic approximation in the form of a rational function of two variables corresponding to the angular and spatial frequencies has been obtained for the transfer function of the system. A hyperbolic partial differential equation describing the general form of the incident pulse envelope transformation upon diffraction by a resonant diffraction grating has been derived from the transfer function. A solution of this equation has been obtained for the case of normal incidence of a pulse with a central frequency lying near the guided-mode resonance of a diffraction structure. The presented results of numerical simulations of pulse diffraction by a resonant grating show profound changes in the pulse envelope shape that closely correspond to the proposed theoretical description. The results of the paper can be applied in creating new devices for optical pulse shape transformation, in optical information processing problems, and analog optical computations.

Electrical control of calcium oscillations in mesenchymal stem cells using microsecond pulsed electric fields.

Science.gov (United States)

Hanna, Hanna; Andre, Franck M; Mir, Lluis M

2017-04-20

Human mesenchymal stem cells are promising tools for regenerative medicine due to their ability to differentiate into many cellular types such as osteocytes, chondrocytes and adipocytes amongst many other cell types. These cells present spontaneous calcium oscillations implicating calcium channels and pumps of the plasma membrane and the endoplasmic reticulum. These oscillations regulate many basic functions in the cell such as proliferation and differentiation. Therefore, the possibility to mimic or regulate these oscillations might be useful to regulate mesenchymal stem cells biological functions. One or several electric pulses of 100 μs were used to induce Ca 2+ spikes caused by the penetration of Ca 2+ from the extracellular medium, through the transiently electropermeabilized plasma membrane, in human adipose mesenchymal stem cells from several donors. Attached cells were preloaded with Fluo-4 AM and exposed to the electric pulse(s) under the fluorescence microscope. Viability was also checked. According to the pulse(s) electric field amplitude, it is possible to generate a supplementary calcium spike with properties close to those of calcium spontaneous oscillations, or, on the contrary, to inhibit the spontaneous calcium oscillations for a very long time compared to the pulse duration. Through that inhibition of the oscillations, Ca 2+ oscillations of desired amplitude and frequency could then be imposed on the cells using subsequent electric pulses. None of the pulses used here, even those with the highest amplitude, caused a loss of cell viability. An easy way to control Ca 2+ oscillations in mesenchymal stem cells, through their cancellation or the addition of supplementary Ca 2+ spikes, is reported here. Indeed, the direct link between the microsecond electric pulse(s) delivery and the occurrence/cancellation of cytosolic Ca 2+ spikes allowed us to mimic and regulate the Ca 2+ oscillations in these cells. Since microsecond electric pulse delivery

Determination of propylthiouracil in pharmaceuticals by differential pulse voltammetry using a cathodically pretreated boron-doped diamond electrode

Energy Technology Data Exchange (ETDEWEB)

Sartori, Elen Romao [Universidade Estadual de Londrina, PR (Brazil). Dept. de Quimica; Trench, Aline Barrios; Rocha-Filho, Romeu C.; Fatibello-Filho, Orlando, E-mail: bello@ufscar.br [Universidade Federal de Sao Carlos (UFSCAR), SP (Brazil). Dept. de Quimica

2013-09-15

A simple procedure is described for the determination of propylthiouracil (PTU) by differential pulse voltammetry (DPV) using a cathodically pretreated boron-doped diamond (BDD) electrode. Cyclic voltammetry studies indicate that the oxidation of PTU is irreversible at a peak potential of 1.42 V (vs. Ag/AgCl (3.0 mol L{sup -1} KCl)) in a Britton-Robinson (BR) buffer solution (pH 2.0). Under optimized conditions, the obtained analytical curve was linear (r = 0.9985) for the PTU concentration range of 1.0 to 29.1 {mu}mol L{sup -1} in a BR buffer solution (pH 2.0), with a detection limit of 0.90 {mu}mol L{sup -1}. The proposed method was successfully applied in the determination of PTU in pharmaceutical samples, with results in agreement at a 95% confidence level with those obtained using an official titration method. (author)

Estudo polarográfico sobre a determinação de Fe(III utilizando-se a técnica da polarografia de pulso diferencial Polarographic study about the determination of Fe(III using the technique of differencial pulse polarography

Directory of Open Access Journals (Sweden)

Luiz Manoel Aleixo

2001-12-01

Full Text Available A differential pulse polarographic study with the objective to determine iron (III in presense of copper (II in a supporting electrolyte based on citrate - EDTA was made. The best experimental conditions found were a supporting electrolyte of citrate 0.25 mol L-1, EDTA 0.050 mol L-1 and KNO3 0.50 mol L-1, pH 5.00. In this media iron (III showed a polarographic peak in -0.08 V and the copper (II in -0.34 V, both vs. Ag/AgCl (saturated KCl. Thus, a analytical method was developed and applied to determine iron (III in brass alloy, a matrix were copper is in large excess over iron. The results obtained showed no interference of copper in the iron determination. The value of 0.21% of iron in the sample alloy composition was obtained and the method was validated by atomic absortion and recovery test, and the results exhibited a good agreement with the proposed method.

Increasing the bit rate in OCDMA systems using pulse position modulation techniques.

Science.gov (United States)

Arbab, Vahid R; Saghari, Poorya; Haghi, Mahta; Ebrahimi, Paniz; Willner, Alan E

2007-09-17

We have experimentally demonstrated two novel pulse position modulation techniques, namely Double Pulse Position Modulation (2-PPM) and Differential Pulse Position Modulation (DPPM) in Time-Wavelength OCDMA systems that will operate at a higher bit rate compared to traditional OOK-OCDMA systems with the same bandwidth. With 2-PPM technique, the number of active users will be more than DPPM while their bit rate is almost the same. Both techniques provide variable quality of service in OCDMA networks.

A photodiode amplifier system for pulse-by-pulse intensity measurement of an x-ray free electron laser.

Science.gov (United States)

Kudo, Togo; Tono, Kensuke; Yabashi, Makina; Togashi, Tadashi; Sato, Takahiro; Inubushi, Yuichi; Omodani, Motohiko; Kirihara, Yoichi; Matsushita, Tomohiro; Kobayashi, Kazuo; Yamaga, Mitsuhiro; Uchiyama, Sadayuki; Hatsui, Takaki

2012-04-01

We have developed a single-shot intensity-measurement system using a silicon positive-intrinsic-negative (PIN) photodiode for x-ray pulses from an x-ray free electron laser. A wide dynamic range (10(3)-10(11) photons/pulse) and long distance signal transmission (>100 m) were required for this measurement system. For this purpose, we developed charge-sensitive and shaping amplifiers, which can process charge pulses with a wide dynamic range and variable durations (ns-μs) and charge levels (pC-μC). Output signals from the amplifiers were transmitted to a data acquisition system through a long cable in the form of a differential signal. The x-ray pulse intensities were calculated from the peak values of the signals by a waveform fitting procedure. This system can measure 10(3)-10(9) photons/pulse of ~10 keV x-rays by direct irradiation of a silicon PIN photodiode, and from 10(7)-10(11) photons/pulse by detecting the x-rays scattered by a diamond film using the silicon PIN photodiode. This system gives a relative accuracy of ~10(-3) with a proper gain setting of the amplifiers for each measurement. Using this system, we succeeded in detecting weak light at the developmental phase of the light source, as well as intense light during lasing of the x-ray free electron laser. © 2012 American Institute of Physics

Generation of short electrical pulses based on bipolar transistorsny

Directory of Open Access Journals (Sweden)

M. Gerding

2004-01-01

Full Text Available A system for the generation of short electrical pulses based on the minority carrier charge storage and the step recovery effect of bipolar transistors is presented. Electrical pulses of about 90 ps up to 800 ps duration are generated with a maximum amplitude of approximately 7V at 50Ω. The bipolar transistor is driven into saturation and the base-collector and base-emitter junctions become forward biased. The resulting fast switch-off edge of the transistor’s output signal is the basis for the pulse generation. The fast switching of the transistor occurs as a result of the minority carriers that have been injected and stored across the base-collector junction under forward bias conditions. If the saturated transistor is suddenly reverse biased the pn-junction will appear as a low impedance until the stored charge is depleted. Then the impedance will suddenly increase to its normal high value and the flow of current through the junction will turn to zero, abruptly. A differentiation of the output signal of the transistor results in two short pulses with opposite polarities. The differentiating circuit is implemented by a transmission line network, which mainly acts as a high pass filter. Both the transistor technology (pnp or npn and the phase of the transfer function of the differentating circuit influence the polarity of the output pulses. The pulse duration depends on the transistor parameters as well as on the transfer function of the pulse shaping network. This way of generating short electrical pulses is a new alternative for conventional comb generators based on steprecovery diodes (SRD. Due to the three-terminal structure of the transistor the isolation problem between the input and the output signal of the transistor network is drastically simplified. Furthermore the transistor is an active element in contrast to a SRD, so that its current gain can be used to minimize the power of the driving signal.

Analytic model of electron pulse propagation in ultrafast electron diffraction experiments

International Nuclear Information System (INIS)

Michalik, A.M.; Sipe, J.E.

2006-01-01

We present a mean-field analytic model to study the propagation of electron pulses used in ultrafast electron diffraction experiments (UED). We assume a Gaussian form to characterize the electron pulse, and derive a system of ordinary differential equations that are solved quickly and easily to give the pulse dynamics. We compare our model to an N-body numerical simulation and are able to show excellent agreement between the two result sets. This model is a convenient alternative to time consuming and computationally intense N-body simulations in exploring the dynamics of UED electron pulses, and as a tool for refining UED experimental designs

Robust photonic differentiator employing slow light effect in photonic crystal waveguide

DEFF Research Database (Denmark)

Yan, Siqi; Cheng, Ziwei; Frandsen, Lars Hagedorn

2017-01-01

A robust photonic DIFF exploiting the slow light effect in a photonic crystal waveguide is proposed and experimentally demonstrated. Input Gaussian pulses with full-width halfmaximums ranging from 2.7 ps to 81.4 ps can be accurately differentiated.......A robust photonic DIFF exploiting the slow light effect in a photonic crystal waveguide is proposed and experimentally demonstrated. Input Gaussian pulses with full-width halfmaximums ranging from 2.7 ps to 81.4 ps can be accurately differentiated....

Thermodynamic analysis of a pulse tube engine

International Nuclear Information System (INIS)

Moldenhauer, Stefan; Thess, André; Holtmann, Christoph; Fernández-Aballí, Carlos

2013-01-01

Highlights: ► Numerical model of the pulse tube engine process. ► Proof that the heat transfer in the pulse tube is out of phase with the gas velocity. ► Proof that a free piston operation is possible. ► Clarifying the thermodynamic working principle of the pulse tube engine. ► Studying the influence of design parameters on the engine performance. - Abstract: The pulse tube engine is an innovative simple heat engine based on the pulse tube process used in cryogenic cooling applications. The working principle involves the conversion of applied heat energy into mechanical power, thereby enabling it to be used for electrical power generation. Furthermore, this device offers an opportunity for its wide use in energy harvesting and waste heat recovery. A numerical model has been developed to study the thermodynamic cycle and thereby help to design an experimental engine. Using the object-oriented modeling language Modelica, the engine was divided into components on which the conservation equations for mass, momentum and energy were applied. These components were linked via exchanged mass and enthalpy. The resulting differential equations for the thermodynamic properties were integrated numerically. The model was validated using the measured performance of a pulse tube engine. The transient behavior of the pulse tube engine’s underlying thermodynamic properties could be evaluated and studied under different operating conditions. The model was used to explore the pulse tube engine process and investigate the influence of design parameters.

Pulse Propagation on close conductors

CERN Document Server

Dieckmann, A

2001-01-01

The propagation and reflection of arbitrarily shaped pulses on non-dispersive parallel conductors of finite length with user defined cross section is simulated employing the discretized telegraph equation. The geometry of the system of conductors and the presence of dielectric material determine the capacities and inductances that enter the calculation. The values of these parameters are found using an iterative Laplace equation solving procedure and confirmed for certain calculable geometries including the line charge inside a box. The evolving pulses and the resulting crosstalk can be plotted at any instant and - in the Mathematica notebook version of this report - be looked at in an animation. As an example a differential pair of microstrips as used in the ATLAS vertex detector is analysed.

Electrochemical Behavior of Quinoxalin-2-one Derivatives at Mercury Electrodes and Its Analytical Use

Directory of Open Access Journals (Sweden)

Milan Zimpl

2012-01-01

Full Text Available Derivatives of quinoxalin-2-one are interesting compounds with potential pharmacological activity. From this point of view, understanding of their electrochemical behavior is of great importance. In the present paper, a mechanism of electrochemical reduction of quinoxalin-2-one derivatives at mercury dropping electrode was proposed. Pyrazine ring was found to be the main electroactive center undergoing a pH-dependent two-electron reduction process. The molecule protonization of nitrogen in the position 4 precedes the electron acceptance forming a semiquinone radical intermediate which is relatively stable in acidic solutions. Its further reduction is manifested by separated current signal. A positive mesomeric effect of the nonprotonized amino group in the position 7 of the derivative III accelerates the semiquinone reduction yielding a single current wave. The suggested reaction mechanism was verified by means of direct current polarography, differential pulse, cyclic and elimination voltammetry, and coulometry with subsequent GC/MS analysis. The understanding of the mechanism was applied in developing of analytical method for the determination of the studied compounds.

Electrochemical behavior of quinoxalin-2-one derivatives at mercury electrodes and its analytical use.

Science.gov (United States)

Zimpl, Milan; Skopalova, Jana; Jirovsky, David; Bartak, Petr; Navratil, Tomas; Sedonikova, Jana; Kotoucek, Milan

2012-01-01

Derivatives of quinoxalin-2-one are interesting compounds with potential pharmacological activity. From this point of view, understanding of their electrochemical behavior is of great importance. In the present paper, a mechanism of electrochemical reduction of quinoxalin-2-one derivatives at mercury dropping electrode was proposed. Pyrazine ring was found to be the main electroactive center undergoing a pH-dependent two-electron reduction process. The molecule protonization of nitrogen in the position 4 precedes the electron acceptance forming a semiquinone radical intermediate which is relatively stable in acidic solutions. Its further reduction is manifested by separated current signal. A positive mesomeric effect of the nonprotonized amino group in the position 7 of the derivative III accelerates the semiquinone reduction yielding a single current wave. The suggested reaction mechanism was verified by means of direct current polarography, differential pulse, cyclic and elimination voltammetry, and coulometry with subsequent GC/MS analysis. The understanding of the mechanism was applied in developing of analytical method for the determination of the studied compounds.

Solubilization of insoluble zinc compounds by Gluconacetobacter diazotrophicus and the detrimental action of zinc ion (Zn2+) and zinc chelates on root knot nematode Meloidogyne incognita.

Science.gov (United States)

Saravanan, V S; Kalaiarasan, P; Madhaiyan, M; Thangaraju, M

2007-03-01

To examine the zinc (Zn) solubilization potential and nematicidal properties of Gluconacetobacter diazotrophicus. Atomic Absorption Spectrophotometer, Differential Pulse Polarography and Gas Chromatography Coupled Mass Spectrometry were used to estimate the total Zn and Zn(2+) ions and identify the organic acids present in the culture supernatants. The effect of culture filtrate of Zn-amended G. diazotrophicus PAl5 on Meloidogyne incognita in tomato was examined under gnotobiotic conditions. Gluconacetobacter diazotrophicus PAl5 effectively solubilized the Zn compounds tested and 5-ketogluconic acid was identified as the major organic acid aiding the solubilization of zinc oxide. The presence of Zn compounds in the culture filtrates of G. diazotrophicus enhanced the mortality and reduced the root penetration of M. incognita under in vitro conditions. 5-ketogluconic acid produced by G. diazotrophicus mediated the solubilization process and the available Zn(2+) ions enhanced the nematicidal activity of G. diazotrophicus against M. incognita. Zn solubilization and enhanced nematicidal activity of Zn-amended G. diazotrophicus provides the possibility of exploiting it as a plant growth promoting bacteria.

Development of a pulse shape discrimination circuit

International Nuclear Information System (INIS)

Ye Bangjiao; Fan Wei; Fan Yangmei; Yu Xiaoqi; Mei Wen; Wang Zhongmin; Han Rongdian; Xiao Zhenxi

1994-01-01

A pulse shape discrimination circuit was designed and used in an experiment measuring double-differential cross sections of (n, charged particle) reaction; to identify p, α and γ. The performance of the circuit was tested. With this circuit, excellent identification of p, α and γ was obtained. ((orig.))

Detecting cm-scale hot spot over 24-km-long single-mode fiber by using differential pulse pair BOTDA based on double-peak spectrum.

Science.gov (United States)

Diakaridia, Sanogo; Pan, Yue; Xu, Pengbai; Zhou, Dengwang; Wang, Benzhang; Teng, Lei; Lu, Zhiwei; Ba, Dexin; Dong, Yongkang

2017-07-24

In distributed Brillouin optical fiber sensor when the length of the perturbation to be detected is much smaller than the spatial resolution that is defined by the pulse width, the measured Brillouin gain spectrum (BGS) experiences two or multiple peaks. In this work, we propose and demonstrate a technique using differential pulse pair Brillouin optical time-domain analysis (DPP-BOTDA) based on double-peak BGS to enhance small-scale events detection capability, where two types of single mode fiber (main fiber and secondary fiber) with 116 MHz Brillouin frequency shift (BFS) difference have been used. We have realized detection of a 5-cm hot spot at the far end of 24-km single mode fiber by employing a 50-cm spatial resolution DPP-BOTDA with only 1GS/s sampling rate (corresponding to 10 cm/point). The BFS at the far end of 24-km sensing fiber has been measured with 0.54 MHz standard deviation which corresponds to a 0.5°C temperature accuracy. This technique is simple and cost effective because it is implemented using the similar experimental setup of the standard BOTDA, however, it should be noted that the consecutive small-scale events have to be separated by a minimum length corresponding to the spatial resolution defined by the pulse width difference.

Column carbon dioxide and water vapor measurements by an airborne triple-pulse integrated path differential absorption lidar: novel lidar technologies and techniques with path to space

Science.gov (United States)

Singh, U. N.; Petros, M.; Refaat, T. F.; Yu, J.; Ismail, S.

2017-09-01

The 2-micron wavelength region is suitable for atmospheric carbon dioxide (CO2) measurements due to the existence of distinct absorption features for the gas at this wavelength region [1]. For more than 20 years, researchers at NASA Langley Research Center (LaRC) have developed several high-energy and high repetition rate 2-micron pulsed lasers [2]. Currently, LaRC team is engaged in designing, developing and demonstrating a triple-pulsed 2-micron direct detection Integrated Path Differential Absorption (IPDA) lidar to measure the weighted-average column dry-air mixing ratios of carbon dioxide (XCO2) and water vapor (XH2O) from an airborne platform [1, 3-5]. This novel technique allows measurement of the two most dominant greenhouse gases, simultaneously and independently, using a single instrument. This paper will provide status and details of the development of this airborne 2-micron triple-pulse IPDA lidar. The presented work will focus on the advancement of critical IPDA lidar components. Updates on the state-of-the-art triple-pulse laser transmitter will be presented including the status of seed laser locking, wavelength control, receiver and detector upgrades, laser packaging and lidar integration. Future plans for IPDA lidar ground integration, testing and flight validation will also be discussed. This work enables new Earth observation measurements, while reducing risk, cost, size, volume, mass and development time of required instruments.

Improved pulse-height store for A/D conversion

Energy Technology Data Exchange (ETDEWEB)

Casoli, P [Montedel S.p.a., Laben Division, Via Bassini 15, Milano, Italy; Maranesi, P [Politecnico di Milano (Italy). Centro Studi Nucleari E. Fermi

1979-11-15

A new pulse-height store is described. Suitable contrivances improve integral linearity and reduce the differential errors that generally occur at signal amplitudes near the lower threshold. No degradations appear at high rates of input events. The electrical specifications of the pulse-height store are determined through a series of measurements described in the final part of the paper. In order to test the circuit in the most significant way, it has been connected to a fast successive-approximation conversion module which uses the sliding-scale technique for channel width equalisation, thus implementing a complete analog-to-digital converter (ADC) for nuclear spectrometry. The performances of the pulse-height store have been deduced from the behavior of the whole system.

Schwann cells promote neuronal differentiation of bone marrow ...

African Journals Online (AJOL)

It has been suggested that the BMSCs have the capacity to differentiate into neurons under specific experimental conditions, using chemical factors. In this study, we showed that BMSCs can be induced to differentiate into neuron-like cells when they are co-cultured with Schwann cells by Brdu pulse label technology.

Kinematical vortices in double photoionization of helium by attosecond pulses

Science.gov (United States)

Djiokap, J. M. Ngoko; Meremianin, A. V.; Manakov, N. L.; Hu, S. X.; Madsen, L. B.; Starace, Anthony F.

2017-07-01

Two-armed helical vortex structures are predicted in the two-electron momentum distributions produced in double photoionization (DPI) of the He atom by a pair of time-delayed elliptically polarized attosecond pulses with opposite helicities. These predictions are based upon both a first-order perturbation theory analysis and numerical solutions of the two-electron, time-dependent Schrödinger equation in six spatial dimensions. The helical vortex structures originate from Ramsey interference of a pair of ionized two-electron wave packets, each having a total angular momentum of unity, and appear in the sixfold differential DPI probability distribution for any energy partitioning between the two electrons. The vortex structures are exquisitely sensitive to the time delay between the two pulses, their relative phase, their ellipticity, and their handedness; moreover, they occur in a variety of electron detection geometries. However, the vortex structures only occur when the angular separation β =cos-1(p̂1.p̂2) between the electron momenta p1 and p2 is held fixed. The vortex structures can also be observed in the fourfold differential DPI probability distribution obtained by averaging the sixfold differential probability over the emission angles of one electron. Such kinematical vortices are a general phenomenon that may occur in any ionization process, initiated by two time-delayed short pulses with opposite ellipticities, for particular detection geometries.

Base adsorption calorimetry for characterising surface acidity: a comparison between pulse flow and conventional ''static'' techniques

International Nuclear Information System (INIS)

Felix, S.P.; Savill-Jowitt, C.; Brown, D.R.

2005-01-01

A pulsed flow adsorption microcalorimeter (pulse-FMC) has been developed by modifying a Setaram 111. It is tested in comparison with a conventional pulsed static adsorption microcalorimeter (pulse-SMC) for characterising surface acidity of solid acid catalysts. Small pulses of 1% ammonia in helium are delivered to an activated catalyst sample and its surface acidity is differentially profiled in terms of the molar enthalpy of ammonia adsorption (ΔH ads o ) using a combination of differential scanning calorimeter (DSC) and a downstream thermal conductivity detector (TCD). The pulsing action and its sequences are controlled by in-house developed software and the TCD output also is logged into a PC. Thus, the pulse-FMC is fully automated. Two sulfonated polystyrene resin-type catalysts, Amberlyst 15 and Amberlyst 35, a zeolite of the type H + -ZSM-5 (CT 410) and an acid activated clay (Fulcat 220) are characterised at appropriate temperatures using both the new technique and the conventional static base adsorption method. ΔH ads o versus surface coverage profiles of all the four catalysts obtained from both pulse-FMC and the conventional method are found to be comparable. Results are interpreted in terms of the extent to which NH 3 adsorption on the catalysts surface is under thermodynamic control in the two methods

Pulse thermal energy transport/storage system

Science.gov (United States)

Weislogel, Mark M.

1992-07-07

A pulse-thermal pump having a novel fluid flow wherein heat admitted to a closed system raises the pressure in a closed evaporator chamber while another interconnected evaporator chamber remains open. This creates a large pressure differential, and at a predetermined pressure the closed evaporator is opened and the opened evaporator is closed. This difference in pressure initiates fluid flow in the system.

The application of pulse shape discrimination in NE 213 to neutron spectrometry

International Nuclear Information System (INIS)

Perkins, L.J.; Scott, M.C.

1979-01-01

The use of a zero-crossing pulse shape discrimination technique to distinguish protons from alpha particles in NE 213 is described, and a theoretical analysis is performed to predict the zero crossing characteristics. It is shown that, irrespective of the particular method of pulse shape discrimination employed, the pulse shape at low energies no longer uniquely determines the particle type for electrons, protons, alpha particles or 12 C nuclei, and the general limitations of pulse shape discrimination in NE 213 are deduced. The use of an alpha discrimination technique is then discribed, enabling neutron spectra to be unfolded from the measured detector response using a differential code. (orig.)

Differential B-dot and D-dot monitors for current and voltage measurements on a 20-MA 3-MV pulsed-power accelerator

International Nuclear Information System (INIS)

Shoup, Roy Willlam; Gilliland, Terrance Leo; Lee, James R.; Speas, Christopher Shane; Kim, Alexandre A.; Struve, Kenneth William; York, Mathew William; Leifeste, Gordon T.; Rochau, Gregory Alan; Sharpe, Arthur William; Stygar, William A.; Porter, John Larry Jr.; Wagoner, Tim C.; Reynolds, Paul Gerard; Slopek, Jeffrey Scott; Moore, William B.S.; Dinwoodie, Thomas Albert; Woodring, R.M.; Broyles, Robin Scott; Mills, Jerry Alan; Melville, J.A.; Dudley, M.E.; Androlewicz, K.E.; Mourning, R.W.; Moore, J.K.; Serrano, Jason Dimitri; Ives, H.C.; Johnson, M.F.; Peyton, B.P.; Leeper, Ramon Joe; Savage, Mark Edward; Donovan, Guy Louis; Spielman, R.B.; Seamen, Johann F.

2007-01-01

We have developed a system of differential-output monitors that diagnose current and voltage in the vacuum section of a 20-MA 3-MV pulsed-power accelerator. The system includes 62 gauges: 3 current and 6 voltage monitors that are fielded on each of the accelerator's 4 vacuum-insulator stacks, 6 current monitors on each of the accelerator's 4 outer magnetically insulated transmission lines (MITLs), and 2 current monitors on the accelerator's inner MITL. The inner-MITL monitors are located 6 cm from the axis of the load. Each of the stack and outer-MITL current monitors comprises two separate B-dot sensors, each of which consists of four 3-mm-diameter wire loops wound in series. The two sensors are separately located within adjacent cavities machined out of a single piece of copper. The high electrical conductivity of copper minimizes penetration of magnetic flux into the cavity walls, which minimizes changes in the sensitivity of the sensors on the 100-ns time scale of the accelerator's power pulse. A model of flux penetration has been developed and is used to correct (to first order) the B-dot signals for the penetration that does occur. The two sensors are designed to produce signals with opposite polarities; hence, each current monitor may be regarded as a single detector with differential outputs. Common-mode-noise rejection is achieved by combining these signals in a 50-(Omega) balun. The signal cables that connect the B-dot monitors to the balun are chosen to provide reasonable bandwidth and acceptable levels of Compton drive in the bremsstrahlung field of the accelerator. A single 50-ω cable transmits the output signal of each balun to a double-wall screen room, where the signals are attenuated, digitized (0.5-ns/sample), numerically compensated for cable losses, and numerically integrated. By contrast, each inner-MITL current monitor contains only a single B-dot sensor. These monitors are fielded in opposite-polarity pairs. The two signals from a pair are

AIREK-PUL, Periodic Kinetics Problems of Pulsed Reactors

International Nuclear Information System (INIS)

Inzaghi, A.; Misenta, R.

1984-01-01

1 - Nature of physical problem solved: Solves periodic problems about the kinetics of pulsed reactors or problems where the reactivity has rapid variations. The program uses two constant steps for the integration of the system of differential equations, the first step during the first half-period and the second step during the second half-period. Available for either single or double precision. 2 - Method of solution: The differential equations are integrated using the fourth-order Runge-Kutta method as modified by E.R. Cohen (Geneva Conference, 1958). 3 - Restrictions on the complexity of the problem: The maximum number of differential equations that can be solved simultaneously is 50

Precise ion optical description of strip-line pulsed magnetic lenses

International Nuclear Information System (INIS)

Varentsov, D.; Spiller, P.; Eickhoff, H.; Hoffmann, D.H.H.

2002-01-01

A specific computer code has been developed to investigate ion optical properties of a new generation of pulsed strip-line high current magnets. The code is based on a modern 'Differential Algebra' computational technique and it is able to calculate transfer matrices of pulsed strip-line magnets up to arbitrary order. The realistic three-dimensional distribution of the magnetic field in pulsed lenses as well as all the fringing field effects are taken into account in the simulations. We have demonstrated, that for precise description of such magnets one cannot use the existing ion optical codes where ideal multipole field distributions and fringing fields, typical for conventional iron-dominated magnets are assumed. The transfer matrix elements of pulsed strip-line lenses differ significantly from those of conventional magnets, especially in higher orders

Co-Culture with Human Osteoblasts and Exposure to Extremely Low Frequency Pulsed Electromagnetic Fields Improve Osteogenic Differentiation of Human Adipose-Derived Mesenchymal Stem Cells

Directory of Open Access Journals (Sweden)

Sabrina Ehnert

2018-03-01

Full Text Available Human adipose-derived mesenchymal stem cells (Ad-MSCs have been proposed as suitable option for cell-based therapies to support bone regeneration. In the bone environment, Ad-MSCs will receive stimuli from resident cells that may favor their osteogenic differentiation. There is recent evidence that this process can be further improved by extremely low frequency pulsed electromagnetic fields (ELF-PEMFs. Thus, the project aimed at (i investigating whether co-culture conditions of human osteoblasts (OBs and Ad-MSCs have an impact on their proliferation and osteogenic differentiation; (ii whether this effect can be further improved by repetitive exposure to two specific ELF-PEMFs (16 and 26 Hz; (iii and the effect of these ELF-PEMFs on human osteoclasts (OCs. Osteogenic differentiation was improved by co-culturing OBs and Ad-MSCs when compared to the individual mono-cultures. An OB to Ad-MSC ratio of 3:1 had best effects on total protein content, alkaline phosphatase (AP activity, and matrix mineralization. Osteogenic differentiation was further improved by both ELF-PEMFs investigated. Interestingly, only repetitive exposure to 26 Hz ELF-PEMF increased Trap5B activity in OCs. Considering this result, a treatment with gradually increasing frequency might be of interest, as the lower frequency (16 Hz could enhance bone formation, while the higher frequency (26 Hz could enhance bone remodeling.

Pulsed Electromagnetic Field Regulates MicroRNA 21 Expression to Activate TGF-β Signaling in Human Bone Marrow Stromal Cells to Enhance Osteoblast Differentiation

Directory of Open Access Journals (Sweden)

Nagarajan Selvamurugan

2017-01-01

Full Text Available Pulsed electromagnetic fields (PEMFs have been documented to promote bone fracture healing in nonunions and increase lumbar spinal fusion rates. However, the molecular mechanisms by which PEMF stimulates differentiation of human bone marrow stromal cells (hBMSCs into osteoblasts are not well understood. In this study the PEMF effects on hBMSCs were studied by microarray analysis. PEMF stimulation of hBMSCs’ cell numbers mainly affected genes of cell cycle regulation, cell structure, and growth receptors or kinase pathways. In the differentiation and mineralization stages, PEMF regulated preosteoblast gene expression and notably, the transforming growth factor-beta (TGF-β signaling pathway and microRNA 21 (miR21 were most highly regulated. PEMF stimulated activation of Smad2 and miR21-5p expression in differentiated osteoblasts, and TGF-β signaling was essential for PEMF stimulation of alkaline phosphatase mRNA expression. Smad7, an antagonist of the TGF-β signaling pathway, was found to be miR21-5p’s putative target gene and PEMF caused a decrease in Smad7 expression. Expression of Runx2 was increased by PEMF treatment and the miR21-5p inhibitor prevented the PEMF stimulation of Runx2 expression in differentiating cells. Thus, PEMF could mediate its effects on bone metabolism by activation of the TGF-β signaling pathway and stimulation of expression of miR21-5p in hBMSCs.

Nanostructured platform for the detection of Neisseria gonorrhoeae using electrochemical impedance spectroscopy and differential pulse voltammetry

International Nuclear Information System (INIS)

Singh, R.; Matharu, Z.; Srivastava, A.K.; Sood, S.; Gupta, R.K.; Malhotra, B.D.

2012-01-01

We report on a nanocomposite based genosensor for the detection of Neisseria gonorrhoeae, a bacterium causing the sexually transmitted disease gonorrhoea. Amino-labeled probe DNA was covalently immobilized on electrochemically prepared polyaniline and iron oxide (PANI-Fe 3 O 4 ) nanocomposite film on an indium tin oxide (ITO) electrode. Scanning electron microscopy, transmission electron microscopy, electrochemical impedance spectroscopy (EIS) and differential pulse voltammetry (DPV) techniques have been employed to characterize surface of the modified electrode. The genosensor has detection limits of 1 x 10 -15 M and 1 x 10 -17 M, respectively, using the EIS and DPV techniques. This biosensor can discriminate a complementary sequence from a single-base mismatch and from non-complementary DNA, and has been utilized for detection of DNA extracted from N. gonorrhoeae culture, and from patient samples with N. gonorrhoeae. It is found to exhibit good specificity for N. gonorrhoeae species and shows no response towards non-gonorrhoeae type of Neisseria species (NgNs) and other gram-negative bacterias (GNBs). The affinity constant for hybridization calculated using the Langmuir adsorption isotherm model is found to be 3. 39 x 10 8 M -1 . (author)

Differential-output B-dot and D-dot monitors for current and voltage measurements on a 20-MA, 3-MV pulsed-power accelerator

Directory of Open Access Journals (Sweden)

T. C. Wagoner

2008-10-01

Full Text Available We have developed a system of differential-output monitors that diagnose current and voltage in the vacuum section of a 20-MA 3-MV pulsed-power accelerator. The system includes 62 gauges: 3 current and 6 voltage monitors that are fielded on each of the accelerator’s 4 vacuum-insulator stacks, 6 current monitors on each of the accelerator’s 4 outer magnetically insulated transmission lines (MITLs, and 2 current monitors on the accelerator’s inner MITL. The inner-MITL monitors are located 6 cm from the axis of the load. Each of the stack and outer-MITL current monitors comprises two separate B-dot sensors, each of which consists of four 3-mm-diameter wire loops wound in series. The two sensors are separately located within adjacent cavities machined out of a single piece of copper. The high electrical conductivity of copper minimizes penetration of magnetic flux into the cavity walls, which minimizes changes in the sensitivity of the sensors on the 100-ns time scale of the accelerator’s power pulse. A model of flux penetration has been developed and is used to correct (to first order the B-dot signals for the penetration that does occur. The two sensors are designed to produce signals with opposite polarities; hence, each current monitor may be regarded as a single detector with differential outputs. Common-mode-noise rejection is achieved by combining these signals in a 50-Ω balun. The signal cables that connect the B-dot monitors to the balun are chosen to provide reasonable bandwidth and acceptable levels of Compton drive in the bremsstrahlung field of the accelerator. A single 50-Ω cable transmits the output signal of each balun to a double-wall screen room, where the signals are attenuated, digitized (0.5-ns/sample, numerically compensated for cable losses, and numerically integrated. By contrast, each inner-MITL current monitor contains only a single B-dot sensor. These monitors are fielded in opposite-polarity pairs. The two

Delay differential equations for mode-locked semiconductor lasers.

Science.gov (United States)

Vladimirov, Andrei G; Turaev, Dmitry; Kozyreff, Gregory

2004-06-01

We propose a new model for passive mode locking that is a set of ordinary delay differential equations. We assume a ring-cavity geometry and Lorentzian spectral filtering of the pulses but do not use small gain and loss and weak saturation approximations. By means of a continuation method, we study mode-locking solutions and their stability. We find that stable mode locking can exist even when the nonlasing state between pulses becomes unstable.

Identification of fractional-order systems with time delays using block pulse functions

Science.gov (United States)

Tang, Yinggan; Li, Ning; Liu, Minmin; Lu, Yao; Wang, Weiwei

2017-07-01

In this paper, a novel method based on block pulse functions is proposed to identify continuous-time fractional-order systems with time delays. First, the operational matrices of block pulse functions for fractional integral operator and time delay operator are derived. Then, these operational matrices are applied to convert the continuous-time fractional-order systems with time delays to an algebraic equation. Finally, the system's parameters along with the differentiation orders and the time delays are all simultaneously estimated through minimizing a quadric error function. The proposed method reduces the computation complexity of the identification process, and also it does not require the system's differentiation orders to be commensurate. The effectiveness of the proposed method are demonstrated by several numerical examples.

Differential die-away analysis system response modeling and detector design

International Nuclear Information System (INIS)

Jordan, K.A.; Gozani, T.; Vujic, J.

2008-01-01

Differential die-away-analysis (DDAA) is a sensitive technique to detect presence of fissile materials such as 235 U and 239 Pu. DDAA uses a high-energy (14 MeV) pulsed neutron generator to interrogate a shipping container. The signature is a fast neutron signal hundreds of microseconds after the cessation of the neutron pulse. This fast neutron signal has decay time identical to the thermal neutron diffusion decay time of the inspected cargo. The theoretical aspects of a cargo inspection system based on the differential die-away technique are explored. A detailed mathematical model of the system is developed, and experimental results validating this model are presented

Pulsed electric field sensor based on original waveform measurement

International Nuclear Information System (INIS)

Ma Liang; Wu Wei; Cheng Yinhui; Zhou Hui; Li Baozhong; Li Jinxi; Zhu Meng

2010-01-01

The paper introduces the differential and original waveform measurement principles for pulsed E-field, and develops an pulsed E-field sensor based on original waveform measurement along with its theoretical correction model. The sensor consists of antenna, integrator, amplifier and driver, optic-electric/electric-optic conversion module and transmission module. The time-domain calibration in TEM cell indicates that, its risetime response is shorter than 1.0 ns, and the output pulse width at 90% of the maximum amplitude is wider than 10.0 μs. The output amplitude of the sensor is linear to the electric field intensity in a dynamic range of 20 dB. The measurement capability can be extended to 10 V/m or 50 kV/m by changing the system's antenna and other relative modules. (authors)

Electrochemistry of uranium in sodium chloroaluminate melts

International Nuclear Information System (INIS)

D'olieslager, W.; Meuris, F.; Heerman, L.

1990-01-01

The electrochemical behaviour of uranium was studied in basic, NaCl-saturated NaAlCl 4 melts at 175 deg C. Solutions of UO 3 exhibit two oxidation/reduction waves (cyclic voltammetry). Analysis of the peak currents (cyclic voltammetry), the limiting currents (pulse polarography) and the non-linear log i-t curves (anodic controlled potential coulometry) leads to the conclusion that uranium(IV) in the basic chloroaluminate melt exists as two different species in slow equilibrium with one another, of which only one species can be oxidized to U(VI). (author) 16 refs.; 7 figs.; 3 tabs

Design of Electric Field Sensors for Measurement of Electromagnetic Pulse

Directory of Open Access Journals (Sweden)

Hui ZHANG

2014-01-01

Full Text Available In this paper, a D-dot electric field sensor and a fiber-optic transmission electric field sensor are developed for measurement of electromagnetic pulse. The D-dot sensor is a differential model sensor without source and has a simple structure. The fiber-optic transmission sensor is in the type of small dipole antenna, which uses its outside shielding layer as a pair of antennas. Design of the sensor circuit and the test system are introduced in this paper. A calibration system for these pulsed field sensors is established and the test results verified the ability of the developed sensors for measurement of the standard electromagnetic pulse field (the half peak width is 25 ns and the rising time is 2.5 ns.

Simultaneous determination of paracetamol and ibuprofen in pharmaceutical samples by differential pulse voltammetry using a boron-doped diamond electrode

Energy Technology Data Exchange (ETDEWEB)

Lima, Amanda B.; Guimaraes, Carlos F.R.C.; Verly, Rodrigo M.; Silva, Leonardo M. da [Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, MG (Brazil). Departamento de Quimica; Torres, Livia M.F.C.; Carvalho, Junior, Alvaro D.; Santos, Wallans T. P. dos, E-mail: wallanst@ufvjm.edu.br [Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, MG (Brazil). Departamento de Farmacia

2014-03-15

This work presents a simple, fast and low-cost methodology for the simultaneous determination of paracetamol (PC) and ibuprofen (IB) in pharmaceutical formulations by differential pulse voltammetry using a boron-doped diamond (BDD) electrode. A well-defined oxidation peak was observed using the BDD electrode for each analyte (0.85 V for PC and 1.72 V for IB (vs. Ag/AgCl)) in 0.1 mol L{sup -1} H{sub 2}SO{sub 4} solution containing 10% (v/v) of ethanol. Calibration curves for the simultaneous determination of PC and IB showed a linear response for both drugs in a concentration range of 20 to 400 μmol L{sup -1} (r{sup 2} = 0.999), with a detection limit of 7.1 μmol L{sup -1} for PC and 3.8 μmol L{sup -1} for IB. The addition-recovery studies in samples were about 100% and the results were validated by chromatographic methods. (author)

Simultaneous determination of paracetamol and ibuprofen in pharmaceutical samples by differential pulse voltammetry using a boron-doped diamond electrode

International Nuclear Information System (INIS)

Lima, Amanda B.; Guimaraes, Carlos F.R.C.; Verly, Rodrigo M.; Silva, Leonardo M. da; Torres, Livia M.F.C.; Carvalho Junior, Alvaro D.; Santos, Wallans T. P. dos

2014-01-01

This work presents a simple, fast and low-cost methodology for the simultaneous determination of paracetamol (PC) and ibuprofen (IB) in pharmaceutical formulations by differential pulse voltammetry using a boron-doped diamond (BDD) electrode. A well-defined oxidation peak was observed using the BDD electrode for each analyte (0.85 V for PC and 1.72 V for IB (vs. Ag/AgCl)) in 0.1 mol L -1 H 2 SO 4 solution containing 10% (v/v) of ethanol. Calibration curves for the simultaneous determination of PC and IB showed a linear response for both drugs in a concentration range of 20 to 400 μmol L -1 (r 2 = 0.999), with a detection limit of 7.1 μmol L -1 for PC and 3.8 μmol L -1 for IB. The addition-recovery studies in samples were about 100% and the results were validated by chromatographic methods. (author)

Pulse pile-up. I: Short pulses

International Nuclear Information System (INIS)

Wilkinson, D.H.

1990-07-01

The search for rare large pulses against an intense background of smaller ones involves consideration of pulse pile-up. Approximate methods are presented, based on ruin theory, by which the probability of such pile-up may be estimated for pulses of arbitrary form and of arbitrary pulse-height distribution. These methods are checked against cases for which exact solutions are available. The present paper is concerned chiefly with short pulses of finite total duration. (Author) (5 refs., 24 figs.)

Fissile mass estimation by pulsed neutron source interrogation

Energy Technology Data Exchange (ETDEWEB)

Israelashvili, I., E-mail: israelashvili@gmail.com [Nuclear Research Center of the Negev, P.O.B 9001, Beer Sheva 84190 (Israel); Dubi, C.; Ettedgui, H.; Ocherashvili, A. [Nuclear Research Center of the Negev, P.O.B 9001, Beer Sheva 84190 (Israel); Pedersen, B. [Nuclear Security Unit, Institute for Transuranium Elements, Joint Research Centre, Via E. Fermi, 2749, 21027 Ispra (Italy); Beck, A. [Nuclear Research Center of the Negev, P.O.B 9001, Beer Sheva 84190 (Israel); Roesgen, E.; Crochmore, J.M. [Nuclear Security Unit, Institute for Transuranium Elements, Joint Research Centre, Via E. Fermi, 2749, 21027 Ispra (Italy); Ridnik, T.; Yaar, I. [Nuclear Research Center of the Negev, P.O.B 9001, Beer Sheva 84190 (Israel)

2015-06-11

Passive methods for detecting correlated neutrons from spontaneous fissions (e.g. multiplicity and SVM) are widely used for fissile mass estimations. These methods can be used for fissile materials that emit a significant amount of fission neutrons (like plutonium). Active interrogation, in which fissions are induced in the tested material by an external continuous source or by a pulsed neutron source, has the potential advantages of fast measurement, alongside independence of the spontaneous fissions of the tested fissile material, thus enabling uranium measurement. Until recently, using the multiplicity method, for uranium mass estimation, was possible only for active interrogation made with continues neutron source. Pulsed active neutron interrogation measurements were analyzed with techniques, e.g. differential die away analysis (DDA), which ignore or implicitly include the multiplicity effect (self-induced fission chains). Recently, both, the multiplicity and the SVM techniques, were theoretically extended for analyzing active fissile mass measurements, made by a pulsed neutron source. In this study the SVM technique for pulsed neutron source is experimentally examined, for the first time. The measurements were conducted at the PUNITA facility of the Joint Research Centre in Ispra, Italy. First promising results, of mass estimation by the SVM technique using a pulsed neutron source, are presented.

Study of 18-Pulse Rectifier Utilizing Hexagon Connected 3-Phase to 9-Phase Transformer

Directory of Open Access Journals (Sweden)

Ahmad Saudi Samosir

2008-04-01

Full Text Available The 18-pulse converter, using Y or -connected differential autotransformer, is very interesting since it allows natural high power factor correction. The lowest input current harmonic components are the 17th and 19th. The Transformer is designed to feed three six-pulse bridge rectifiers displaced in phase by 200. This paper present a high power factor three-phase rectifier bases on 3-phase to 9-phase transformer and 18-pulse rectifier. The 9-phase polygon-connected transformer followed by 18-pulse diode rectifiers ensures the fundamental concept of natural power factor correction. Simulation results to verify the proposed concept are shown in this paper.

A sandwich-like differential B-dot based on EACVD polycrystalline diamond slice

Science.gov (United States)

Xu, P.; Yu, Y.; Xu, L.; Zhou, H. Y.; Qiu, C. J.

2018-06-01

In this article, we present a method of mass production of a standardized high-performance differential B-dot magnetic probe together with the magnetic field measurement in a pulsed current device with the current up to hundreds of kilo-Amperes. A polycrystalline diamond slice produced in an Electron Assisted Chemical Vapor Deposition device is used as the base and insulating material to imprint two symmetric differential loops for the magnetic field measurement. The SP3 carbon bond in the cubic lattice structure of diamond is confirmed by Raman spectra. The thickness of this slice is 20 μm. A gold loop is imprinted onto each surface of the slice by using the photolithography technique. The inner diameter, width, and thickness of each loop are 0.8 mm, 50 μm, and 1 μm, respectively. It provides a way of measuring the pulsed magnetic field with a high spatial and temporal resolution, especially in limited space. This differential magnetic probe has demonstrated a very good common-mode rejection rate through the pulsed magnetic field measurement.

Proposal of Application of Pulsed Vision Chip for Retinal Prosthesis

Science.gov (United States)

Ohta, Jun; Yoshida, Norikatsu; Kagawa, Keiichiro; Nunoshita, Masahiro

2002-04-01

A vision chip based on pulse frequency modulation (PFM) is proposed as a retinal prosthesis device for use in subretinal implantation. A pixel circuit of PFM has been fabricated using standard CMOS technology. A dynamic range of 40 dB is demonstrated at a low power supply voltage of 1 V. It is found that the competition between the charge current to the photodiode and the photocurrent affects the output pulse characteristics under the conditionds of low power supply voltage and strong light illumination. For in vitro and in vivo experiments, two methods of improving the PFM circuits are considered. One is controlling the pulse frequency. By adding one transistor to the PFM circuit, the output pulse frequency can be experimentally controlled by a factor of two. The other is using a biphasic output, which is required to keep a charge balance in a living body. By introducing differential circuits, the biphasic output has been confirmed by simulation.

Chemical behaviour of plutonium in natural, aquatic systems: Hydrolysis, carbonate complexation and redox reactions

International Nuclear Information System (INIS)

Lierse, C.

1985-01-01

In order to clear up the geochemical behaviour of plutonium and its migration mechanisms in groundwater, hydrolysis, redox behaviour, compound formation in carbonate solutions and colloid formation were examined in groundwater conditions, i.e. at pH values between 5 and 8 and at redox potentials of between -300 and +700 mV. Solubility measurements, spectroscopic processes (UV, VIS, IR spectroscopy and laser induced photoacoustic spectroscopy) and electrochemical processes (cyclic voltammetry, differential pulse polarography) are used as methods of investigation. The hydrolysis constants of Pu IV and Pu VI and the solubility product of Pu (OH) 4 were determined and hydrolysis products of divalent and trivalent type are described. From solubility experiments, the stability constants for Pu (IV) carbonate compounds and the solubility product for the carbonate system of stable bodies of Pu (OH) 2 CO 3 were calculated. Using absorption spectroscopy, the disproportionate kinetics of Pu (V) in carbonate was determined at various pH values. A slow, but continuous, reduction in Pu (VI) was found in carbonate solution, which was derived from radiolytic effects. The speed of this auto-reduction was determined, depending on various experimental parameters. (orig./RB) [de

Assay of Aliphatic Phthalates in Polymer Products by Sensitive Polarographic Method: Health and Environmental Issue

Directory of Open Access Journals (Sweden)

Munawar Saeed

2010-06-01

Full Text Available A faster, simpler and sensitive method was developed for determination of aliphatic phthalates using differential pulse polarography (DPP as standard technique. The choice and concentration of base electrolyte, solvent, initial potential, effect of water addition and interference by other phthalates were the main parameters to optimize for enhancement of peak current and to obtain well-defined polarogram with lower background current using 1.3 x 10-4 M di-butyl phthalate (DBP solution. Best results were obtained in the presence of tetra methyl ammonium bromide (TMAB as electrolyte in methanol solvent with initial potential, -1.4 V. A linear calibration plot was observed in the range of 3 x 10-7 – 1.6 x 10-4 M DBP solution as aliphatic phthalates with lower detection limit of 5.9 x 10-8 M and linear regression coefficient of 0.9987. The developed polarographic method was successfully applied for analysis of aliphtaic phthalates in various samples of locally available polymer products such as baby toys, nipples, teethers, infusion blood bags and shopping bags. The results of the current method were compared with those obtained by a reported method and good agreement was found between them.

Response of an oscillatory differential delay equation to a single stimulus.

Science.gov (United States)

Mackey, Michael C; Tyran-Kamińska, Marta; Walther, Hans-Otto

2017-04-01

Here we analytically examine the response of a limit cycle solution to a simple differential delay equation to a single pulse perturbation of the piecewise linear nonlinearity. We construct the unperturbed limit cycle analytically, and are able to completely characterize the perturbed response to a pulse of positive amplitude and duration with onset at different points in the limit cycle. We determine the perturbed minima and maxima and period of the limit cycle and show how the pulse modifies these from the unperturbed case.

Realtime aspects of pulse-to-pulse modulation

International Nuclear Information System (INIS)

Steiner, R.; Riedel, C.; Roesch, W.

1992-01-01

The pulse-to-pulse modulation of the SIS-ESR control system is described. Fast response to operator interaction and to changes in process conditions is emphasized as well as the essential part played by the timing system in pulse-to-pulse modulation. (author)

Modification of Pulsed Electric Field Conditions Results in Distinct Activation Profiles of Platelet-Rich Plasma.

Science.gov (United States)

Frelinger, Andrew L; Gerrits, Anja J; Garner, Allen L; Torres, Andrew S; Caiafa, Antonio; Morton, Christine A; Berny-Lang, Michelle A; Carmichael, Sabrina L; Neculaes, V Bogdan; Michelson, Alan D

2016-01-01

Activated autologous platelet-rich plasma (PRP) used in therapeutic wound healing applications is poorly characterized and standardized. Using pulsed electric fields (PEF) to activate platelets may reduce variability and eliminate complications associated with the use of bovine thrombin. We previously reported that exposing PRP to sub-microsecond duration, high electric field (SMHEF) pulses generates a greater number of platelet-derived microparticles, increased expression of prothrombotic platelet surfaces, and differential release of growth factors compared to thrombin. Moreover, the platelet releasate produced by SMHEF pulses induced greater cell proliferation than plasma. To determine whether sub-microsecond duration, low electric field (SMLEF) bipolar pulses results in differential activation of PRP compared to SMHEF, with respect to profiles of activation markers, growth factor release, and cell proliferation capacity. PRP activation by SMLEF bipolar pulses was compared to SMHEF pulses and bovine thrombin. PRP was prepared using the Harvest SmartPreP2 System from acid citrate dextrose anticoagulated healthy donor blood. PEF activation by either SMHEF or SMLEF pulses was performed using a standard electroporation cuvette preloaded with CaCl2 and a prototype instrument designed to take into account the electrical properties of PRP. Flow cytometry was used to assess platelet surface P-selectin expression, and annexin V binding. Platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF), endothelial growth factor (EGF) and platelet factor 4 (PF4), and were measured by ELISA. The ability of supernatants to stimulate proliferation of human epithelial cells in culture was also evaluated. Controls included vehicle-treated, unactivated PRP and PRP with 10 mM CaCl2 activated with 1 U/mL bovine thrombin. PRP activated with SMLEF bipolar pulses or thrombin had similar light scatter profiles, consistent with the presence of platelet

Modification of Pulsed Electric Field Conditions Results in Distinct Activation Profiles of Platelet-Rich Plasma.

Directory of Open Access Journals (Sweden)

Andrew L Frelinger

Full Text Available Activated autologous platelet-rich plasma (PRP used in therapeutic wound healing applications is poorly characterized and standardized. Using pulsed electric fields (PEF to activate platelets may reduce variability and eliminate complications associated with the use of bovine thrombin. We previously reported that exposing PRP to sub-microsecond duration, high electric field (SMHEF pulses generates a greater number of platelet-derived microparticles, increased expression of prothrombotic platelet surfaces, and differential release of growth factors compared to thrombin. Moreover, the platelet releasate produced by SMHEF pulses induced greater cell proliferation than plasma.To determine whether sub-microsecond duration, low electric field (SMLEF bipolar pulses results in differential activation of PRP compared to SMHEF, with respect to profiles of activation markers, growth factor release, and cell proliferation capacity.PRP activation by SMLEF bipolar pulses was compared to SMHEF pulses and bovine thrombin. PRP was prepared using the Harvest SmartPreP2 System from acid citrate dextrose anticoagulated healthy donor blood. PEF activation by either SMHEF or SMLEF pulses was performed using a standard electroporation cuvette preloaded with CaCl2 and a prototype instrument designed to take into account the electrical properties of PRP. Flow cytometry was used to assess platelet surface P-selectin expression, and annexin V binding. Platelet-derived growth factor (PDGF, vascular endothelial growth factor (VEGF, endothelial growth factor (EGF and platelet factor 4 (PF4, and were measured by ELISA. The ability of supernatants to stimulate proliferation of human epithelial cells in culture was also evaluated. Controls included vehicle-treated, unactivated PRP and PRP with 10 mM CaCl2 activated with 1 U/mL bovine thrombin.PRP activated with SMLEF bipolar pulses or thrombin had similar light scatter profiles, consistent with the presence of platelet

Effect of electrical pulse on the precipitates and material strength of 2024 aluminum alloy

Energy Technology Data Exchange (ETDEWEB)

Wu, Weichao, E-mail: weichao127@gmail.com; Wang, Yongjun, E-mail: t.s.wu@163.com; Wang, Junbiao, E-mail: wangjunb@nwpu.edu.cn; Wei, Shengmin, E-mail: weism@nwpu.edu.cn

2014-07-01

The effect of electrical pulse on the metastable precipitates and material strength of Al–Cu–Mg based 2024 aluminum alloy was investigated by means of tensile tests, hardness measurement, transmission electron microscopy and differential scanning calorimetry. The experimental results show that the electrical pulse passing through the naturally aged 2024 alloy can cause an electrical pulse retrogression effect which is characterized by the decrease of material strength and the appearance of Portevin–Le Chatelier (PLC) effect. More electrical pulses under higher current densities are more efficient in causing the electrical pulse retrogression effect. TEM and DSC experimental results reveal that, the electrical pulse retrogression effect is owing to the dissolution of the metastable precipitates in naturally aged 2024 alloy. Compared with the traditional retrogression heat treatment that heats the aluminum alloys through bulk heating in furnace for short time to reduce their material strength, the electrical pulse retrogression effect occurs at a much lower temperature and the pulse treated alloy can nearly restore to its original strength at a faster speed at room temperature.

applications of artificial neural networks to resolution of differential ...

African Journals Online (AJOL)

spisska

Disturbed Differential Pulse Polarographic Peaks in the Region of Hydrogen ... represent the experimental behaviour of the system when the exact description is ... equations and the values of physico-chemical constants.8 The characteristics ...

Pulsed rf excited spectrometer having improved pulse width control

International Nuclear Information System (INIS)

1977-01-01

RF excitation for a spectrometer is obtained by pulse width modulating an RF carrier to produce the desired broadband RF exciting spectrum. The RF excitation includes a train of composite RF pulses, each composite pulse having a primary pulse portion of a first RF phase and a second pulse portion of a second RF phase opposite that of the first. In this manner, the finite rise and fall times of the primary pulse portion are compensated for by the corresponding rise and fall times of the secondary pulse portion. The primary pulse portion is lengthened by an amount equal to the secondary pulse portion so that the secondary pulse portion cancels the added primary pulse portion. In a spectrometer, the compensating second pulse component removes certain undesired side bands of the RF excitation caused by the finite rise and fall times of the applied RF pulses. The compensating second pulse component removes certain undesired side bands associated with each of the resonant lines of the excited resonance spectrum of the sample under analysis, particularly for wide band RF excitation

Resonance – Journal of Science Education | Indian Academy of ...

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 9; Issue 9. Polarography. V Lakshminarayanan. General Article Volume 9 Issue 9 September 2004 pp 51-61. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/009/09/0051-0061. Keywords. Polarography ...

Bipolar pulse generator for intense pulsed ion beam accelerator

International Nuclear Information System (INIS)

Ito, H.; Igawa, K.; Kitamura, I.; Masugata, K.

2007-01-01

A new type of pulsed ion beam accelerator named ''bipolar pulse accelerator'' (BPA) has been proposed in order to improve the purity of intense pulsed ion beams. To confirm the principle of the BPA, we developed a bipolar pulse generator for the bipolar pulse experiment, which consists of a Marx generator and a pulse forming line (PFL) with a rail gap switch on its end. In this article, we report the first experimental result of the bipolar pulse and evaluate the electrical characteristics of the bipolar pulse generator. When the bipolar pulse generator was operated at 70% of the full charge condition of the PFL, the bipolar pulse with the first (-138 kV, 72 ns) and the second pulse (+130 kV, 70 ns) was successfully obtained. The evaluation of the electrical characteristics indicates that the developed generator can produce the bipolar pulse with fast rise time and sharp reversing time

ATLAS FCal Diagnostics using the Calibration Pulse

CERN Document Server

Rutherfoord, J

2004-01-01

The calibration pulser in the ATLAS Forward Calorimeter electronics is used to 1) directly calibrate the warm, active electronics and 2) diagnose the cold, passive electronics chain all the way to the liquid argon electrodes. The study presented here shows that reflections of the calibration pulse coming from discontinuities located at or between the warm preamplifier and the electrode can differentiate and identify all known defects so far observed in this chain.

Propagation of a probe pulse inside a Bose–Einstein condensate under conditions of electromagnetically induced transparency

International Nuclear Information System (INIS)

Barberis-Blostein, Pablo; Aguilar-Loreto, Omar

2015-01-01

We obtain a partial differential equation for a pulse travelling inside a Bose–Einstein condensate under conditions of electromagnetically induced transparency. The equation is valid for a weak probe pulse. We solve the equation for the case of a three-level BEC in Λ configuration with one of its ground state spatial profiles initially constant. The solution characterizes, in detail, the effect that the evolution of the condensate wave function has on pulse propagation, including the process of stopping and releasing it. (invited comment)

Dendritic cells pulsed with Pythium insidiosum (1,3)(1,6)-β-glucan, Heat-inactivated zoospores and immunotherapy prime naïve T cells to Th1 differentiation in vitro.

Science.gov (United States)

Ledur, Pauline C; Tondolo, Juliana S M; Jesus, Francielli P K; Verdi, Camila M; Loreto, Érico S; Alves, Sydney H; Santurio, Janio M

2018-03-01

Pythiosis is a life-threatening disease caused by the fungus-like microorganism Pythium insidiosum that can lead to death if not treated. Since P. insidiosum has particular cell wall characteristics, pythiosis is difficult to treat, as it does not respond well to traditional antifungal drugs. In our study, we investigated a new immunotherapeutic approach with potential use in treatment and in the acquisition of immunity against pythiosis. Dendritic cells from both human and mouse, pulsed with P. insidiosum heat-inactivated zoospore, (1,3)(1,6)-β-glucan and the immunotherapeutic PitiumVac ® efficiently induced naïve T cell differentiation in a Th1 phenotype by the activation of specific Th1 cytokine production in vitro. Heat-inactivated zoospores showed the greatest Th1 response among the tested groups, with a significant increase in IL-6 and IFN-γ production in human cells. In mice cells, we also observed a Th17 pathway induction, with an increase on the IL-17A levels in lymphocytes cultured with β-glucan pulsed DCs. These results suggest a potential use of DCs pulsed with P. insidiosum antigens as a new therapeutic strategy in the treatment and acquisition of immunity against pythiosis. Copyright © 2017 Elsevier GmbH. All rights reserved.

Airborne Measurements of CO2 Column Absorption and Range Using a Pulsed Direct-Detection Integrated Path Differential Absorption Lidar

Science.gov (United States)

Abshire, James B.; Riris, Haris; Weaver, Clark J.; Mao, Jianping; Allan, Graham R.; Hasselbrack, William E.; Browell, Edward V.

2013-01-01

We report on airborne CO2 column absorption measurements made in 2009 with a pulsed direct-detection lidar operating at 1572.33 nm and utilizing the integrated path differential absorption technique. We demonstrated these at different altitudes from an aircraft in July and August in flights over four locations in the central and eastern United States. The results show clear CO2 line shape and absorption signals, which follow the expected changes with aircraft altitude from 3 to 13 km. The lidar measurement statistics were also calculated for each flight as a function of altitude. The optical depth varied nearly linearly with altitude, consistent with calculations based on atmospheric models. The scatter in the optical depth measurements varied with aircraft altitude as expected, and the median measurement precisions for the column varied from 0.9 to 1.2 ppm. The altitude range with the lowest scatter was 810 km, and the majority of measurements for the column within it had precisions between 0.2 and 0.9 ppm.

Electrochemical behaviour of β-diketones and their complexes with metals

International Nuclear Information System (INIS)

Kamenev, A.I.; Dzherippa, L.G.; Efimov, I.P.

1985-01-01

Literature on the problems of polarography of β-dicetones and β-dicetonates of metals including rare earths covering the period from sixties up today is reviewed. Conditions, mechanism and practical possibilities of the process are considered. A possibility of using polarography for studying fantomerism in the series of cyclic β-dicetones is noted

All-optical temporal fractional order differentiator using an in-fiber ellipsoidal air-microcavity

Science.gov (United States)

Zhang, Lihong; Sun, Shuqian; Li, Ming; Zhu, Ninghua

2017-12-01

An all-optical temporal fractional order differentiator with ultrabroad bandwidth (~1.6 THz) and extremely simple fabrication is proposed and experimentally demonstrated based on an in-fiber ellipsoidal air-microcavity. The ellipsoidal air-microcavity is fabricated by splicing a single mode fiber (SMF) and a photonic crystal fiber (PCF) together using a simple arc-discharging technology. By changing the arc-discharging times, the propagation loss can be adjusted and then the differentiation order is tuned. A nearly Gaussian-like optical pulse with 3 dB bandwidth of 8 nm is launched into the differentiator and a 0.65 order differentiation of the input pulse is achieved with a processing error of 2.55%. Project supported by the the National Natural Science Foundation of China (Nos. 61522509, 61377002, 61535012), the National High-Tech Research & Development Program of China (No. SS2015AA011002), and the Beijing Natural Science Foundation (No. 4152052). Ming Li was supported in part by the Thousand Young Talent Program.

Pulse on pulse: modulation and signification in Rafael Lozano-Hemmer's Pulse Room

Directory of Open Access Journals (Sweden)

Merete Carlson

2012-06-01

Full Text Available This article investigates the relation between signifying processes and non-signifying material dynamism in the installation Pulse Room (2006 by Mexican Canadian artist Rafael Lozano-Hemmer. In Pulse Room the sense of pulse is ambiguous. Biorhythms are transmitted from the pulsing energy of the visitor's beating heart to the flashing of a fragile light bulb, thereby transforming each light bulb into a register of individual life. But at the same time the flashing light bulbs together produce a chaotically flickering light environment composed by various layers of repetitive rhythms, a vibrant and pulsating “room”. Hence, the visitor in Pulse Room is invited into a complex scenario that continuously oscillates between various aspects of signification (the light bulbs representing individual lives; the pulse itself as the symbolic “rhythm of life” and instants of pure material processuality (flickering light bulbs; polyrhythmic layers. Taking our point of departure in a discussion of Gilles Deleuze's concepts of modulation and signaletic material in relation to electronic media, we examine how the complex orchestration of pulsation between signification and material modulation produces a multilayered sense of time and space that is central to the sensory experience of Pulse Room as a whole. Pulse Room is, at the very same time, a relational subject–object intimacy and an all-encompassing immersive environment modulating continuously in real space-time.

Multiloop soliton and multibreather solutions of the short pulse model equation

International Nuclear Information System (INIS)

Matsuno, Yoshimasa

2007-01-01

We develop a systematic procedure for constructing the multisoliton solutions of the short pulse (SP) model equation which describes the propagation of ultra-short pulses in nonlinear medica. We first introduce a novel hodograph transformation to convert the SP equation into the sine-Gordon (sG) equation. With the soliton solutions of the sG equation, the system of linear partial differential equations governing the inverse mapping can be integrated analytically to obtain the soliton solutions of the SP equation in the form of the parametric representation. By specifying the soliton parameters, we obtain the multiloop and multibreather solutions. We investigate the asymptotic behavior of both solutions and confirm their solitonic feature. The nonsingular breather solutions may play an important role in studying the propagation of ultra-short pulses in an optical fibre. (author)

New laser system for highly sensitive clinical pulse oximetry

Science.gov (United States)

Hamza, Mostafa; Hamza, Mohammad

1996-04-01

This paper describes the theory and design of a new pulse oximeter in which laser diodes and other compact laser sources are used for the measurement of oxygen saturation in patients who are at risk of developing hypoxemia. The technique depends upon illuminating special sites of the skin of the patient with radiation from modulated laser sources at selected wavelengths. The specific laser wavelengths are chosen based on the absorption characteristics of oxyhemoglobin, reduced hemoglobin and other interfering sources for obtaining more accurate measurements. The laser radiation transmitted through the tissue is detected and signal processing based on differential absorption laser spectroscopy is done in such a way to overcome the primary performance limitations of the conventionally used pulse oximetry. The new laser pulse oximeter can detect weak signals and is not affected by other light sources such as surgical lamps, phototherapy units, etc. The detailed description and operating characteristics of this system are presented.

Time pulse profiles on a new data acquisition system for neutron time of flight diffractometer

International Nuclear Information System (INIS)

Venegas, R.; Baeza, L.; Navarro, G.

1999-01-01

A new differential acquisition system was built for a neutron diffuse scattering instrument. We analyze the time, space and velocity behavior of neutron pulse profiles, which can be obtained in a neutron diffuse scattering system of this nature, consisting of a black disc slit chopper and a circular detector bank, in order to design accurate scattering data analyzing methods. Computed direct pulse time spectra and measured spectra show satisfactory agreement. (author)

Gamma compensated pulsed ionization chamber wide range neutron/reactor power measurement system

International Nuclear Information System (INIS)

Ellis, W.H.

1975-01-01

An improved method and system of pulsed mode operation of ionization chambers is described in which a single sensor system with gamma compensation is provided by sampling, squaring, automatic gate selector, and differential amplifier circuit means, employed in relation to chambers sensitized to neutron plus gamma and gamma only to subtract out the gamma component, wherein squaring functions circuits, a supplemental high performance pulse rate system, and operational and display mode selection and sampling gate circuits are utilized to provide automatic wide range linear measurement capability for neutron flux and reactor power. Neon is employed as an additive in the ionization chambers to provide independence of ionized gas kinetics temperature effects, and the pulsed mode of operation provide independence of high temperature insulator leakage effects. (auth)

Validation of a Novel Traditional Chinese Medicine Pulse Diagnostic Model Using an Artificial Neural Network

Directory of Open Access Journals (Sweden)

Anson Chui Yan Tang

2012-01-01

Full Text Available In view of lacking a quantifiable traditional Chinese medicine (TCM pulse diagnostic model, a novel TCM pulse diagnostic model was introduced to quantify the pulse diagnosis. Content validation was performed with a panel of TCM doctors. Criterion validation was tested with essential hypertension. The gold standard was brachial blood pressure measured by a sphygmomanometer. Two hundred and sixty subjects were recruited (139 in the normotensive group and 121 in the hypertensive group. A TCM doctor palpated pulses at left and right cun, guan, and chi points, and quantified pulse qualities according to eight elements (depth, rate, regularity, width, length, smoothness, stiffness, and strength on a visual analog scale. An artificial neural network was used to develop a pulse diagnostic model differentiating essential hypertension from normotension. Accuracy, specificity, and sensitivity were compared among various diagnostic models. About 80% accuracy was attained among all models. Their specificity and sensitivity varied, ranging from 70% to nearly 90%. It suggested that the novel TCM pulse diagnostic model was valid in terms of its content and diagnostic ability.

Development of an advanced Two-Micron triple-pulse IPDA lidar for carbon dioxide and water vapor measurements

Science.gov (United States)

Petros, Mulugeta; Refaat, Tamer F.; Singh, Upendra N.; Yu, Jirong; Antill, Charles; Remus, Ruben; Taylor, Bryant D.; Wong, Teh-Hwa; Reithmaier, Karl; Lee, Jane; Ismail, Syed; Davis, Kenneth J.

2018-04-01

An advanced airborne triple-pulse 2-μm integrated path differential absorption (IPDA) lidar is under development at NASA Langley Research Center that targets both carbon dioxide (CO2) and water vapor (H2O) measurements simultaneously and independently. This lidar is an upgrade to the successfully demonstrated CO2 2-μm double-pulse IPDA. Upgrades include high-energy, highrepetition rate 2-μm triple-pulse laser transmitter, innovative wavelength control and advanced HgCdTe (MCT) electron-initiated avalanche photodiode detection system. Ground testing and airborne validation plans are presented.

Short-pulse optical parametric chirped-pulse amplification for the generation of high-power few-cycle pulses

International Nuclear Information System (INIS)

Major, Zs.; Osterhoff, J.; Hoerlein, R.; Karsch, S.; Fuoloep, J.A.; Krausz, F.; Ludwig-Maximilians Universitaet, Muenchen

2006-01-01

Complete test of publication follows. In the quest for a way to generate ultrashort, high-power, few-cycle laser pulses the discovery of optical parametric amplification (OPA) has opened up to the path towards a completely new regime, well beyond that of conventional laser amplification technology. The main advantage of this parametric amplification process is that it allows for an extremely broad amplification bandwidth compared to any known laser amplifier medium. When combined with the chirped-pulse amplification (CPA) principle (i.e. OPCPA), on one hand pulses of just 10 fs duration and 8 mJ pulse energy have been demonstrated. On the other hand, pulse energies of up to 30 J were also achieved on a different OPCPA system; the pulse duration in this case, however, was 100 fs. In order to combine ultrashort pulse durations (i.e. pulses in the few-cycle regime) with high pulse energies (i.e. in the Joule range) we propose tu pump on OPCPA chain with TW-scale short pulses (100 fs - 1 ps instead of > 100 ps of previous OPCPA systems) delivered by a conventional CPA system. This approach inherently improves the conditions for generating high-power ultrashort pulses using OPCPA in the following ways. Firstly, the short pump pulse duration reduces the necessary stretching factor for the seed pulse, thereby increasing stretching and compression fidelity. Secondly, also due to the shortened pump pulse duration, a much higher contrast is achieved. Finally, the significantly increased pump power makes the use of thinner OPCPA crystals possible, which implies an even broader amplification bandwidth, thereby allowing for even shorter pulses. We carried out theoretical investigations to show the feasibility of such a set-up. Alongside these studies we will also present preliminary experimental results of an OPCPA system pumped by the output of our Ti:Sapphire ATLAS laser, currently delivering 350 mJ in 43 fs. An insight into the planned scaling of this technique to petawatt

Cellular automata for spatiotemporal pattern formation from reaction–diffusion partial differential equations

International Nuclear Information System (INIS)

Ohmori, Shousuke; Yamazaki, Yoshihiro

2016-01-01

Ultradiscrete equations are derived from a set of reaction–diffusion partial differential equations, and cellular automaton rules are obtained on the basis of the ultradiscrete equations. Some rules reproduce the dynamical properties of the original reaction–diffusion equations, namely, bistability and pulse annihilation. Furthermore, other rules bring about soliton-like preservation and periodic pulse generation with a pacemaker, which are not obtained from the original reaction–diffusion equations. (author)

Pulsed electron beam generation with fast repetitive double pulse system

Energy Technology Data Exchange (ETDEWEB)

Sharma, Surender Kumar; Deb, Pankaj; Shyam, Anurag, E-mail: surender80@gmail.com [Energetics and Electromagnetics Division, Bhabha Atomic Research Centre, Visakhapatnam (India); Sharma, Archana [Accelerator and Pulse Power Division, Bhabha Atomic Research Centre, Mumbai (India)

2014-07-01

Longer duration high voltage pulse (∼ 100 kV, 260 ns) is generated and reported using helical pulse forming line in compact geometry. The transmission line characteristics of the helical pulse forming line are also used to develop fast repetition double pulse system with very short inter pulse interval. It overcomes the limitations caused due to circuit parameters, power supplies and load characteristics for fast repetitive high voltage pulse generation. The high voltage double pulse of 100 kV, 100 ns with an inter pulse repetition interval of 30 ns is applied across the vacuum field emission diode for pulsed electron beam generation. The electron beam is generated from cathode material by application of negative high voltage (> 100 kV) across the diode by explosive electron emission process. The vacuum field emission diode is made of 40 mm diameter graphite cathode and SS mesh anode. The anode cathode gap was 6 mm and the drift tube diameter was 10 cm. The initial experimental results of pulsed electron beam generation with fast repetitive double pulse system are reported and discussed. (author)

High intensity heat pulse problem

International Nuclear Information System (INIS)

Yalamanchili, R.

1977-01-01

The use of finite-difference methods for the solution of partial differential equations is common in both design and research and development because of the advance of computers. The numerical methods for the unsteady heat diffusion equation received most attention not only because of heat transfer problems but also happened to be the basis for any study of parabolic partial differential equations. It is common to test the heat equation first even the methods developed for complex nonlinear parabolic partial differential equations arising in fluid mechanics or convective heat transfer. It is concluded that the finite-element method is conservative in both stability and monoscillation characteristics than the finite-difference method but not as conservative as the method of weighted-residuals. Since the finite-element is unique because of Gurtin's variational principle and numerous finite-differences can be constructed, it is found that some finite-difference schemes are better than the finite-element scheme in accuracy also. Therefore, further attention is focused here on finite-difference schemes only. Various physical problems are considered in the field of heat transfer. These include: numerous problems in steady and unsteady heat conduction; heat pulse problems, such as, plasma torch; problems arising from machining operations, such as, abrasive cut-off and surface grinding. (Auth.)

Pulse Distortion in Saturated Fiber Optical Parametric Chirped Pulse Amplification

DEFF Research Database (Denmark)

Lali-Dastjerdi, Zohreh; Da Ros, Francesco; Rottwitt, Karsten

2012-01-01

Fiber optical parametric chirped pulse amplification is experimentally compared for different chirped pulses in the picosecond regime. The amplified chirped pulses show distortion appearing as pedestals after recompression when the amplifier is operated in saturation.......Fiber optical parametric chirped pulse amplification is experimentally compared for different chirped pulses in the picosecond regime. The amplified chirped pulses show distortion appearing as pedestals after recompression when the amplifier is operated in saturation....

Preparation and electrochemical application of rutin biosensor for differential pulse voltammetric determination of NADH in the presence of acetaminophen

Directory of Open Access Journals (Sweden)

HAMID R. ZARE

2010-10-01

Full Text Available The electrocatalytic behavior of reduced nicotinamide adenine di-nucleotide (NADH was studied at the surface of a rutin biosensor, using various electrochemical methods. According to the results, the rutin biosensor had a strongly electrocatalytic effect on the oxidation of NADH with the overpotential being decreased by about 450 mV as compared to the process at a bare glassy carbon electrode, GCE. This value is significantly greater than the value of 220 mV that was reported for rutin embedded in a lipid-cast film. The kinetic parameters of the electron transfer coefficient, a, and the heterogeneous charge transfer rate constant, kh, for the electrocatalytic oxidation of NADH at the rutin biosensor were estimated. Furthermore, the linear dynamic range; sensitivity and limit of detection for NADH were evaluated using the differential pulse voltammetry method. The advantages of this biosensor for the determination of NADH are excellent catalytic activity and reproducibility, good detection limit and high exchange current density. The rutin biosensor could separate the oxidation peak potentials of NADH and acetaminophen present in the same solution while at a bare GCE, the peak potentials were indistinguishable.

The Graphene/l-Cysteine/Gold-Modified Electrode for the Differential Pulse Stripping Voltammetry Detection of Trace Levels of Cadmium

Directory of Open Access Journals (Sweden)

Yu Song

2016-06-01

Full Text Available Cadmium(II is a common water pollutant with high toxicity. It is of significant importance for detecting aqueous contaminants accurately, as these contaminants are harmful to human health and environment. This paper describes the fabrication, characterization, and application of an environment-friendly graphene (Gr/l-cysteine/gold electrode to detect trace levels of cadmium (Cd by differential pulse stripping voltammetry (DPSV. The influence of hydrogen overflow was decreased and the current response was enhanced because the modified graphene extended the potential range of the electrode. The Gr/l-cysteine/gold electrode showed high electrochemical conductivity, producing a marked increase in anodic peak currents (vs. the glass carbon electrode (GCE and boron-doped diamond (BDD electrode. The calculated detection limits are 1.15, 0.30, and 1.42 µg/L, and the sensitivities go up to 0.18, 21.69, and 152.0 nA·mm−2·µg−1·L for, respectively, the BDD electrode, the GCE, and the Gr/l-cysteine/gold electrode. It was shown that the Gr/l-cysteine/gold-modified electrode is an effective means for obtaining highly selective and sensitive electrodes to detect trace levels of cadmium.

Updating the induction module from single-pulse to double-pulses

International Nuclear Information System (INIS)

Huang Ziping; Wang Huacen; Deng Jianjun

2002-01-01

A double-pulse Linear Induced Accelerator (LIA) module is reconstructed based on a usual simple-pulse LIA module. By changing the length of one of the cables between the inductive cell and the Blumlein pulse forming line, two induction pulses with 90 ns FWHM and 150 kV pulse voltage are generated by the ferrite cores inductive cell. The interval time of the pulses is adjustable by changing the lengths of the cable

Evaluation of bipolar pulse generator for high-purity pulsed ion beam

International Nuclear Information System (INIS)

Ito, H.; Kitamura, I.; Masugata, K.

2008-01-01

A new type of pulsed ion beam accelerator named 'bipolar pulse accelerator (BPA)' has been proposed in order to improve the purity of intense pulsed ion beams. To confirm the principle of the BPA, we developed a bipolar pulse generator, which consists of a Marx generator and a pulse forming line (PFL) with a rail gap switch on its end. In this article, we report the experimental results of the bipolar pulse and evaluate the electrical characteristics of the bipolar pulse generator. When the bipolar pulse generator was operated at 70% of the full charge condition of the PEL, the bipolar pulse with the first (-138 kV, 72 ns) and the second pulse (+130 kV, 70 ns) was successfully obtained. The evaluation of the electrical characteristics indicates that the developed generator can produce the bipolar pulse with fast rise time and sharp reversing time. At present the bipolar pulse generator is installed in the B y type magnetically insulated ion diode and we carry out the experiment on the production of an intense pulsed ion beam by the bipolar pulse accelerator. (author)

Study of time-domain digital pulse shaping algorithms for nuclear signals

International Nuclear Information System (INIS)

Zhou Jianbin; Tuo Xianguo; Zhu Xing; Liu Yi; Zhou Wei; Lei Jiarong

2012-01-01

With the development on high-speed integrated circuit, fast high resolution sampling ADC and digital signal processors are replacing analog shaping amplifier circuit. This paper firstly presents the numerical analysis and simulation on R-C shaping circuit model and C-R shaping circuit model. Mathematic models are established based on 1 st order digital differential method and Kirchhoff Current Law in time domain, and a simulation and error evaluation experiment on an ideal digital signal are carried out with Excel VBA. A digital shaping test for a semiconductor X-ray detector in real time is also presented. Then a numerical analysis for Sallen-Key(S-K) low-pass filter circuit model is implemented based on the analysis of digital R-C and digital C-R shaping methods. By applying the 2 nd order non-homogeneous differential equation,the authors implement a digital Gaussian filter model for a standard exponential-decaying signal and a nuclear pulse signal. Finally, computer simulations and experimental tests are carried out and the results show the possibility of the digital pulse processing algorithms. (authors)

Near threshold pulse shape discrimination techniques in scintillating CsI(Tl) crystals

International Nuclear Information System (INIS)

Wu, S.C.; Yue, Q.; Lai, W.P.; Li, H.B.; Li, J.; Lin, S.T.; Liu, Y.; Singh, V.; Wang, M.Z.; Wong, H.T.; Xin, B.; Zhou, Z.Y.

2004-01-01

There are recent interests with CsI(Tl) scintillating crystals for Dark Matter experiments. The key merit is the capability to differentiate nuclear recoil (nr) signatures from the background β/γ-events due to ambient radioactivity on the basis of their different pulse shapes. One of the major experimental challenges is to perform such pulse shape analysis in the statistics-limited domain where the light output is close to the detection threshold. Using data derived from measurements with low-energy γ's and nuclear recoils due to neutron elastic scatterings, it was verified that the pulse shapes between β/γ-events are different. Several methods of pulse shape discrimination (PSD) are studied, and their relative merits are compared. Full digitization of the pulse shapes is crucial to achieve good discrimination. Advanced software techniques with mean time, neural network and likelihood ratios give rise to satisfactory performance, and are superior to the conventional Double Charge method commonly applied at higher energies. PSD becomes effective starting at a light yield of about 20 photo-electrons. This corresponds to a detection threshold of about 5 keV electron-equivalence energy, or 40-50 keV recoil kinetic energy, in realistic experiments

Effect of pulse electron beam characteristics on internal friction and structural alterations in epoxy

International Nuclear Information System (INIS)

Zaikin, Yu.A.; Ismailova, G.A.; Al-Sheikhly, M.

2007-01-01

Temperature dependence of internal friction is experimentally studied in epoxy irradiated by 2.5 MeV pulse electron beam to different doses. Time dependence of internal friction characteristics associated with radiation-induced processes of polymer scission and cross-linking is analyzed and discussed. Experimental data on kinetics of structural transformations in epoxy are interpreted on the base of analytical solutions of differential equations for free radical accumulation during and after irradiation subject to the pulse irradiation mode and an arbitrary effective order of radical recombination

Pulse oximeter improvement with an ADC-DAC feedback loop and a radial reflectance sensor.

Science.gov (United States)

Thompson, David; Wareing, Austin; Day, Dwight; Warren, Steve

2006-01-01

Pulse oximeter circuitry must meet several design constraints, including the ability to separate a small pulsatile signal component from a large signal baseline. This paper describes pulse oximeter design changes that produced order-of-magnitude improvements in signal quality. The primary changes were (a) the replacement of an analog sample-and-hold-based differentiator circuit with an ADC-DAC feedback loop and (b) the replacement of a side-by-side reflectance sensor design with a radial sensor arrangement that maximizes the pulsatile-to-baseline signal ratio.

Pulse-shaping strategies in short-pulse fiber amplifiers

Energy Technology Data Exchange (ETDEWEB)

Schimpf, Damian Nikolaus

2010-02-09

Ultrashort pulse lasers are an important tool in scientific and industrial applications. However, many applications are demanding higher average powers from these ultrashort pulse sources. This can be achieved by combining direct diode pumping with novel gain media designs. In particular, ultrashort pulse fiber lasers are now delivering average powers in the kW range. However, the design of fiber lasers, producing pulses with high peak-powers, is challenging due to the impact of nonlinear effects. To significantly reduce these detrimental effects in ultrashort pulse fiber amplifers, the combination of chirped pulse amplification (CPA) and large mode area fibers is employed. Using these methods, the pulse energy of fiber lasers has been steadily increasing for the past few years. Recently, a fiber-based CPA-system has been demonstrated which produces pulse energies of around 1 mJ. However, both the stretching and the enlargement of the mode area are limited, and therefore, the impact of nonlinearity is still noticed in systems employing such devices. The aim of this thesis is the analysis of CPA-systems operated beyond the conventional nonlinear limit, which corresponds to accumulated nonlinear phase-shifts around 1 rad. This includes a detailed discussion of the influence of the nonlinear effect self-phase modulation on the output pulse of CPA-systems. An analytical model is presented. Emphasis is placed on the design of novel concepts to control the impact of self-phase modulation. Pulse-shaping is regarded as a powerful tool to accomplish this goal. Novel methods to control the impact of SPM are experimentally demonstrated. The design of these concepts is based on the theoretical findings. Both amplitude- and phase-shaping are studied. Model-based phase-shaping is implemented in a state-of-the-art fiber CPA-system. The influence of the polarization state is also highlighted. Additionally, existing techniques and recent advances are put into context. (orig.)

Pulse-shaping strategies in short-pulse fiber amplifiers

International Nuclear Information System (INIS)

Schimpf, Damian Nikolaus

2010-01-01

Ultrashort pulse lasers are an important tool in scientific and industrial applications. However, many applications are demanding higher average powers from these ultrashort pulse sources. This can be achieved by combining direct diode pumping with novel gain media designs. In particular, ultrashort pulse fiber lasers are now delivering average powers in the kW range. However, the design of fiber lasers, producing pulses with high peak-powers, is challenging due to the impact of nonlinear effects. To significantly reduce these detrimental effects in ultrashort pulse fiber amplifers, the combination of chirped pulse amplification (CPA) and large mode area fibers is employed. Using these methods, the pulse energy of fiber lasers has been steadily increasing for the past few years. Recently, a fiber-based CPA-system has been demonstrated which produces pulse energies of around 1 mJ. However, both the stretching and the enlargement of the mode area are limited, and therefore, the impact of nonlinearity is still noticed in systems employing such devices. The aim of this thesis is the analysis of CPA-systems operated beyond the conventional nonlinear limit, which corresponds to accumulated nonlinear phase-shifts around 1 rad. This includes a detailed discussion of the influence of the nonlinear effect self-phase modulation on the output pulse of CPA-systems. An analytical model is presented. Emphasis is placed on the design of novel concepts to control the impact of self-phase modulation. Pulse-shaping is regarded as a powerful tool to accomplish this goal. Novel methods to control the impact of SPM are experimentally demonstrated. The design of these concepts is based on the theoretical findings. Both amplitude- and phase-shaping are studied. Model-based phase-shaping is implemented in a state-of-the-art fiber CPA-system. The influence of the polarization state is also highlighted. Additionally, existing techniques and recent advances are put into context. (orig.)

Pulse Generator

Science.gov (United States)

Greer, Lawrence (Inventor)

2017-01-01

An apparatus and a computer-implemented method for generating pulses synchronized to a rising edge of a tachometer signal from rotating machinery are disclosed. For example, in one embodiment, a pulse state machine may be configured to generate a plurality of pulses, and a period state machine may be configured to determine a period for each of the plurality of pulses.

Zinc, copper and lead contents of wines. Comparison between the total concentrations by atomic absorption spectrometry and the concentrations of the free ions by polarography

Directory of Open Access Journals (Sweden)

J.-B. Fournier

1998-03-01

Full Text Available In the introduction of this article, some examples of the use of trace element data in the characterisation of viticultural produce are reminded. This paper described the determination of zinc, copper and lead by two techniques based on radically different principles. The atomic absorption spectrometry, applied after the mineralisation of the samples by wet process, allows the determination of the total element contents in wine. The polarography allows the analysis of the concentrations of these elements that are under labile chemical forms, and which are dissolved under the ionic forms Zn++, Cu++ and Pb++. The wines analysed in this study were produced from three different parcels chosen in relation to their geological qualities. The vines implanted on these parcels are strictly identical, and three fermentation techniques were applied to each lots of grapes. The results obtained shows that the copper is only under ionic form and that the temperature of the fermentation influences the total copper level in the final wine. At the opposite, there is no ion Pb++ in the samples, but a long duration of maceration increases the lead content. Concerning zinc, only the ions Zn++ are present in the wine in case of a short duration of the maceration. When this duration increases, some other chemical forms of zinc are dissolved in addition to the ions Zn++ which are instantaneously dissociated in aqueous solutions. The problem of the contamination of grapes by the materials used, the phytosanitary treatments and the atmospheric pollution is discussed. The knowledge of the proportion of a trace element that is under ionic forms is indispensable to evaluate the bio-availability of the considered element and the toxicologic risks. The advent and the expansion of the electrochemical methods is expected as an important advance in this field of research.

Two profitless delays for an SEIRS epidemic disease model with vertical transmission and pulse vaccination

International Nuclear Information System (INIS)

Meng Xinzhu; Jiao Jianjun; Chen Lansun

2009-01-01

Since the investigation of impulsive delay differential equations is beginning, the literature on delay epidemic models with pulse vaccination is not extensive. In this paper, we propose a new SEIRS epidemic disease model with two profitless delays and vertical transmission, and analyze the dynamics behaviors of the model under pulse vaccination. Using the discrete dynamical system determined by the stroboscopic map, we obtain a 'infection-free' periodic solution, further, show that the 'infection-free' periodic solution is globally attractive when some parameters of the model are under appropriate conditions. Using a new modeling method, we obtain sufficient condition for the permanence of the epidemic model with pulse vaccination. We show that time delays, pulse vaccination and vertical transmission can bring different effects on the dynamics behaviors of the model by numerical analysis. Our results also show the delays are 'profitless'. In this paper, the main feature is to introduce two discrete time delays, vertical transmission and impulse into SEIRS epidemic model and to give pulse vaccination strategies.

Pulsed water jet generated by pulse multiplication

Czech Academy of Sciences Publication Activity Database

Dvorský, R.; Sitek, Libor; Sochor, T.

2016-01-01

Roč. 23, č. 4 (2016), s. 959-967 ISSN 1330-3651 R&D Projects: GA MŠk(CZ) LO1406; GA MŠk ED2.1.00/03.0082 Institutional support: RVO:68145535 Keywords : high- pressure pulses * pulse intensifier * pulsed water jet * water hammer effect Subject RIV: JQ - Machines ; Tools Impact factor: 0.723, year: 2016 http://hrcak.srce.hr/163752?lang=en

Determination of halogens, silicon, phosphorus, carbon, sulfur, tributyl phosphate and of free acid in uranyl nitrate solutions

International Nuclear Information System (INIS)

Chu Van Vinh

2003-01-01

High-purity uranium compounds are widely used in nuclear field in the form of uranyl nitrate or uranium oxides. In production of uranium material the estimation and the control of products quality is necessary and very important. Halogens was separated from uranium compounds by steam distillation and they were later determined by high performance liquid chromatography (HPLC) for Cl - , Br - , I - ions. Br - was also determined by spectrophotometric and iodide by the individual pulse polarography. Silicon and phosphorus in uranyl nitrate solutions were determined by the photometric method. Sulfur was determined as sulfate form by the measurement of turbidity by the titrimetry. TBP in kerosene and free acid in aqueous solution were determined by the titration. (author)

Pulsed TRIGA reactor as substitute for long pulse spallation neutron source

International Nuclear Information System (INIS)

Whittemore, W.L.

1999-01-01

TRIGA reactor cores have been used to demonstrate various pulsing applications. The TRIGA reactor fuel (U-ZrH x ) is very robust especially in pulsing applications. The features required to produce 50 pulses per second have been successfully demonstrated individually, including pulse tests with small diameter fuel rods. A partially optimized core has been evaluated for pulses at 50 Hz with peak pulsed power up to 100 MW and an average power up to 10 MW. Depending on the design, the full width at half power of the individual pulses can range between 2000 μsec to 3000 μsec. Until recently, the relatively long pulses (2000 μsec to 3000 μsec) from a pulsed thermal reactor or a long pulse spallation source (LPSS) have been considered unsuitable for time-of-flight measurements of neutron scattering. More recently considerable attention has been devoted to evaluating the performance of long pulse (1000 to 4000 μs) spallation sources for the same type of neutron measurements originally performed only with short pulses from spallation sources (SPSS). Adequate information is available to permit meaningful comparisons between CW, SPSS, and LPSS neutron sources. Except where extremely high resolution is required (fraction of a percent), which does require short pulses, it is demonstrated that the LPSS source with a 1000 msec or longer pulse length and a repetition rate of 50 to 60 Hz gives results comparable to those from the 60 MW ILL (CW) source. For many of these applications the shorter pulse is not necessarily a disadvantage, but it is not an advantage over the long pulse system. In one study, the conclusion is that a 5 MW 2000 μsec LPSS source improves the capability for structural biology studies of macromolecules by at least a factor of 5 over that achievable with a high flux reactor. Recent studies have identified the advantages and usefulness of long pulse neutron sources. It is evident that the multiple pulse TRIGA reactor can produce pulses comparable to

Noise tolerance in wavelength-selective switching of optical differential quadrature-phase-shift-keying pulse train by collinear acousto-optic devices.

Science.gov (United States)

Goto, Nobuo; Miyazaki, Yasumitsu

2014-06-01

Optical switching of high-bit-rate quadrature-phase-shift-keying (QPSK) pulse trains using collinear acousto-optic (AO) devices is theoretically discussed. Since the collinear AO devices have wavelength selectivity, the switched optical pulse trains suffer from distortion when the bandwidth of the pulse train is comparable to the pass bandwidth of the AO device. As the AO device, a sidelobe-suppressed device with a tapered surface-acoustic-wave (SAW) waveguide and a Butterworth-type filter device with a lossy SAW directional coupler are considered. Phase distortion of optical pulse trains at 40 to 100  Gsymbols/s in QPSK format is numerically analyzed. Bit-error-rate performance with additive Gaussian noise is also evaluated by the Monte Carlo method.

Method for pulse to pulse dose reproducibility applied to electron linear accelerators

International Nuclear Information System (INIS)

Ighigeanu, D.; Martin, D.; Oproiu, C.; Cirstea, E.; Craciun, G.

2002-01-01

An original method for obtaining programmed beam single shots and pulse trains with programmed pulse number, pulse repetition frequency, pulse duration and pulse dose is presented. It is particularly useful for automatic control of absorbed dose rate level, irradiation process control as well as in pulse radiolysis studies, single pulse dose measurement or for research experiments where pulse-to-pulse dose reproducibility is required. This method is applied to the electron linear accelerators, ALIN-10 of 6.23 MeV and 82 W and ALID-7, of 5.5 MeV and 670 W, built in NILPRP. In order to implement this method, the accelerator triggering system (ATS) consists of two branches: the gun branch and the magnetron branch. ATS, which synchronizes all the system units, delivers trigger pulses at a programmed repetition rate (up to 250 pulses/s) to the gun (80 kV, 10 A and 4 ms) and magnetron (45 kV, 100 A, and 4 ms).The accelerated electron beam existence is determined by the electron gun and magnetron pulses overlapping. The method consists in controlling the overlapping of pulses in order to deliver the beam in the desired sequence. This control is implemented by a discrete pulse position modulation of gun and/or magnetron pulses. The instabilities of the gun and magnetron transient regimes are avoided by operating the accelerator with no accelerated beam for a certain time. At the operator 'beam start' command, the ATS controls electron gun and magnetron pulses overlapping and the linac beam is generated. The pulse-to-pulse absorbed dose variation is thus considerably reduced. Programmed absorbed dose, irradiation time, beam pulse number or other external events may interrupt the coincidence between the gun and magnetron pulses. Slow absorbed dose variation is compensated by the control of the pulse duration and repetition frequency. Two methods are reported in the electron linear accelerators' development for obtaining the pulse to pulse dose reproducibility: the method

Temporal correlation measurements of pulsed dual CO2 lidar returns. [for atmospheric pollution detection

Science.gov (United States)

Menyuk, N.; Killinger, D. K.

1981-01-01

A pulsed dual-laser direct-detection differential-absorption lidar DIAL system, operating near 10.6 microns, is used to measure the temporal correlation and statistical properties of backscattered returns from specular and diffuse topographic targets. Results show that atmospheric-turbulence fluctuations can effectively be frozen for pulse separation times on the order of 1-3 msec or less. The diffuse target returns, however, yielded a much lower correlation than that obtained with the specular targets; this being due to uncorrelated system noise effects and different statistics for the two types of target returns.

Combination of Echocardiography and Pulse Wave Velocity Provides Clues for the Differentiation between White Coat Hypertension and Hypertension in Postmenopausal Women.

Science.gov (United States)

Suzuki, Hiromichi; Kobayashi, Kazuhiro; Okada, Hirokazu

2014-05-01

To determine whether or not noninvasive assessment of the cardiovascular system can discriminate white coat hypertension and hypertension in postmenopausal women. The major reason is the high prevalence of white coat hypertension in these subjects and the uncertain associations of white coat hypertension with cardiovascular risk. Selected women were required to be naturally or surgically menopausal for at least 1 year but not more than 5 years past their menstrual period. White coat hypertension patients were defined as subjects who had office blood pressures >150/90 mm Hg but who had both systolic and diastolic ambulatory pressures coat hypertension based on the criteria in the trial. Pulse wave patterns were different between subjects with white coat hypertension and those with hypertension. PWV of subjects with white coat hypertension was 1.32 ± 0.33 m/s and that of patients with hypertension was 1.46 ± 0.37 m/s (p coat hypertension could be easily differentiated from hypertension. The combination of blood pressure self-monitoring, echocardiographic data, and PWV can be a powerful indicator for the treatment of hypertension in postmenopausal women.

Application of different methodologies in the preparation of organic matrices for determination of trace elements by differential pulse anodic stripping voltammetry

International Nuclear Information System (INIS)

Sisti, Cristina

2001-01-01

The determination of trace elements in food samples is of great importance for the human health, considering the factors of essentiality and toxicity. On the other hand, the chemical analysis is largely affected for the steps of sample preparation; laboratory contamination of the sample and the reagents or still volatilization and losses of the elements. If these parameters are not controlled the achieved precision and accuracy could be low. In this work, the content of zinc, cadmium, lead and copper was determined in adults diet samples collected by duplicate portion technique and bovine liver, applying the differential pulse anodic stripping voltametry - (DP-ASV) technique. In the digestion of the matrices in acid medium, conventional methodologies were used, conductive heating in open recipients and equipment with microwaves source in open and closed vessels. The best procedure was the sample digestion by microwaves, in closed vessels and the other treatments made in controlled atmosphere with hood laminar-airflow class 100. The established methodology was validated with the use of a certified sample as reference (NIST - bovine liver 1577b). (author)

Investigation on stresses of superconductors under pulsed magnetic fields based on multiphysics model

International Nuclear Information System (INIS)

Yang, Xiaobin; Li, Xiuhong; He, Yafeng; Wang, Xiaojun; Xu, Bo

2017-01-01

Highlights: • The differential equation including temperature and magnetic field was derived for a long cylindrical superconductor. • Thermal stress and electromagnetic stress were studied at the same time under pulse field magnetizing. • The distributions of the magnetic field, the temperature and stresses are studied and compared for two pulse fields of the different duration. • The Role thermal stress and electromagnetic stress play in the process of pulse field magnetizing is discussed. - Abstract: A multiphysics model for the numerical computation of stresses, trapped field and temperature distribution of a infinite long superconducting cylinder is proposed, based on which the stresses, including the thermal stresses and mechanical stresses due to Lorentz force, and trapped fields in the superconductor subjected to pulsed magnetic fields are analyzed. By comparing the results under pulsed magnetic fields with different pulse durations, it is found that the both the mechanical stress due to the electromagnetic force and the thermal stress due to temperature gradient contribute to the total stress level in the superconductor. For pulsed magnetic field with short durations, the thermal stress is the dominant contribution to the total stress, because the heat generated by AC-loss builds up significant temperature gradient in such short durations. However, for a pulsed field with a long duration the gradient of temperature and flux, as well as the maximal tensile stress, are much smaller. And the results of this paper is meaningful for the design and manufacture of superconducting permanent magnets.

Investigation on stresses of superconductors under pulsed magnetic fields based on multiphysics model

Energy Technology Data Exchange (ETDEWEB)

Yang, Xiaobin, E-mail: yangxb@lzu.edu.cn; Li, Xiuhong; He, Yafeng; Wang, Xiaojun; Xu, Bo

2017-04-15

Highlights: • The differential equation including temperature and magnetic field was derived for a long cylindrical superconductor. • Thermal stress and electromagnetic stress were studied at the same time under pulse field magnetizing. • The distributions of the magnetic field, the temperature and stresses are studied and compared for two pulse fields of the different duration. • The Role thermal stress and electromagnetic stress play in the process of pulse field magnetizing is discussed. - Abstract: A multiphysics model for the numerical computation of stresses, trapped field and temperature distribution of a infinite long superconducting cylinder is proposed, based on which the stresses, including the thermal stresses and mechanical stresses due to Lorentz force, and trapped fields in the superconductor subjected to pulsed magnetic fields are analyzed. By comparing the results under pulsed magnetic fields with different pulse durations, it is found that the both the mechanical stress due to the electromagnetic force and the thermal stress due to temperature gradient contribute to the total stress level in the superconductor. For pulsed magnetic field with short durations, the thermal stress is the dominant contribution to the total stress, because the heat generated by AC-loss builds up significant temperature gradient in such short durations. However, for a pulsed field with a long duration the gradient of temperature and flux, as well as the maximal tensile stress, are much smaller. And the results of this paper is meaningful for the design and manufacture of superconducting permanent magnets.

Narrowband pulse-enhanced upconversion of chirped broadband pulses

International Nuclear Information System (INIS)

Zhao, Kun; Yuan, Peng; Zhong, Haizhe; Zhang, Dongfang; Zhu, Heyuan; Qian, Liejia; Chen, Liezun; Wen, Shuangchun

2010-01-01

We propose and demonstrate an efficient sum-frequency mixing scheme based on narrowband and chirped broadband pulses. It combines the advantages of wider spectral acceptance bandwidth and of alleviating the temporal walk-off, which are both beneficial to higher conversion efficiency. Chirped sum-frequency pulses at 455 nm with energy up to 360 µJ, corresponding to a conversion efficiency of ∼ 40%, are obtained and the pulses can be compressed to ∼ 110 fs. The sum-frequency mixing scheme may provide a promising route to the efficient generation of deep-ultraviolet femtosecond pulses

International Year of Pulses 2016 | 2016 International Year of Pulses

Science.gov (United States)

the Year in collaboration with Governments, relevant organizations, non-governmental organizations and the composition of pulses Image 4 Wrapping up the International Year of Pulses The 5 key messages to food security Infographic Pulses and climate change International Year of Pulses 2016 The 68th UN

Electron localization in fragmentation of H2 with CEP stabilized laser pulses

International Nuclear Information System (INIS)

Kremer, Manuel; Fischer, Bettina; Schroeter, Claus Dieter; Feuerstein, Bernold; Moshammer, Robert; Ullrich, Joachim; Rudenko, Artem; Jesus, Vitor L B de

2009-01-01

Fully differential data on ionization and dissociation of H 2 in ultra-short (∼ 6 fs), linearly polarized, intense (∼ 4 . 10 14 W/cm 2 ) laser pulses with stabilized carrier-envelope-phase (CEP) have been measured using a reaction microscope. Depending on the CEP of the laser pulses we see a clear asymmetry in the emission direction of the created protons. Contrary to earlier measurements by Kling et al. we observe the highest asymmetry for kinetic energy releases (proton energy) between 0-2 eV. This excludes the electron re-collision mechanism suggested in [1] as dominant excitation channel and requires another explanation.

Arbitrary waveform generator and differentiator employing an integrated optical pulse shaper

DEFF Research Database (Denmark)

Liao, Shasha; Ding, Yunhong; Dong, Jianji

2015-01-01

We propose and demonstrate an optical arbitrary waveformgenerator and high-order photonic differentiator based on a four-tap finiteimpulse response (FIR) silicon-on-insulator (SOI) on-chip circuit. Based onamplitude and phase modulation of each tap controlled by thermal heaters,we obtain several...

Programmable pulse generator

International Nuclear Information System (INIS)

Xue Zhihua; Lou Binqiao; Duan Xiaohui

2002-01-01

The author introduces the design of programmable pulse generator that is based on a micro-controller and controlled by RS232 interface of personal computer. The whole system has good stability. The pulse generator can produce TTL pulse and analog pulse. The pulse frequency can be selected by EPLD. The voltage amplitude and pulse width of analog pulse can be adjusted by analog switches and digitally-controlled potentiometers. The software development tools of computer is National Instruments LabView5.1. The front panel of this virtual instrumentation is intuitive and easy-to-use. Parameters can be selected and changed conveniently by knob and slide

Application of the ultrashort pulses in bovine dental enamel

International Nuclear Information System (INIS)

Todescan, Carla de Rago

2003-01-01

The interaction of lasers with the hard structures of the teeth, has found the excess of heat as a problem for its utilization. This study analyzes, in vitro, the interaction of the ultrashort pulse laser of Ti:safire (830 nm) with the bovine dental enamel. The system consisted in one main oscillator integrated with an amplifier (CPA). The pulses extracted before the temporal compression inside the amplifier had 30 ps, 1000 Hz and ∼1 mJ. The pulses extracted after the compression had 60 fs, 1000 Hz and ∼0,7 mJ. The M 2 was 1,3, the focal lens 2,5 cm, the focal distance 29,7 and a computerized translation stage x,y,z. We evaluated the amount of tissue removed per pulse,the resulting cavities and the surrounding tissues not irradiated, under OM and SEM. The fluency was the major factor for differentiating the two regimens studied, therefore, the intensity was not so important as we expected in this process. We found: one ablation region in 'cat tongue', one ablation length, one fluency ∼0,7 J/cm 2 for 30 ps and ∼0,5 J/cm 2 for 60 fs (50% of high speed burr), smooth edge for 30 ps and high precision of the sharp edge cut of submicrometric order for 60 fs. (author)

Integrated differential high-voltage transmitting circuit for CMUTs

DEFF Research Database (Denmark)

Llimos Muntal, Pere; Larsen, Dennis Øland; Farch, Kjartan

2015-01-01

In this paper an integrated differential high-voltage transmitting circuit for capacitive micromachined ultrasonic transducers (CMUTs) used in portable ultrasound scanners is designed and implemented in a 0.35 μm high-voltage process. Measurements are performed on the integrated circuit in order...... to assess its performance. The circuit generates pulses at differential voltage levels of 60V, 80V and 100 V, a frequency up to 5MHz and a measured driving strength of 1.75 V/ns with the CMUT connected. The total on-chip area occupied by the transmitting circuit is 0.18 mm2 and the power consumption...

Platinum(II Complexes with Tetradentate Schiff Bases as Ligands: Synthesis, Characterization and Detection of DNA Interaction by Differential Pulse Voltammetry

Directory of Open Access Journals (Sweden)

Lijun Li

2012-01-01

Full Text Available Five sterically hindered platinum(II complexes with tetradentate schiff bases as ligands, [Pt(L] (L= N,N′-bisalicylidene-1,2-ethylenediamine (L1, N,N′-bisalicylidene-1,2-cyclohexanediamine (L2, N,N′-bis(5-hydroxyl-salicylidene-1,2-cyclohexanediamine (L3, N,N′-bisalicylidene-1,2-diphenyl-ethylenediamine (L4 and N,N′-bis(3-tert-butyl-5-methyl-salicylidene-1,2-diphenylethylenediamine (L5 have been synthesized and characterized by IR spectroscopy and elemental analysis. The sterical hindrance of antitumor drug candidates potentially makes them less susceptible to deactivation by sulphur containing proteins and helping to overcome resistance mechanisms. The interaction of these metal complexes with fish sperm single-stranded DNA (ssDNA was studied electrochemically based on the oxidation signals of guanine and adenine. Differential pulse voltammetry was employed to monitor the DNA interaction in solution by using renewable pencil graphite electrode. The results indicate that ligands with different groups can strongly affect the interaction between [Pt(L] complexes and ssDNA due to sterical hindrances and complex [Pt(L1] has the best interaction with DNA among the five complexes.

Mathematical model and simulation of the hydrodynamic of air-pulsed sieve plate columns

International Nuclear Information System (INIS)

Hannappel, J.; Pfeifer, W.; Rathjen, E.

1979-02-01

In this work the dynamic flow events in an air pulsed sieve plate column are described by a simulation model. The model consists of a system of differential equations. The pressure built up by the pulsed air is brought to equilibrium with the pressure losses of the oscillating liquid column in the pulsation tube and in the column. In case of definition of the a) column geometry, b) integral holdup of the column, c) density of the participating phases, d) control times of the pulsed air valves, e) pulse repetition frequency and pulsed air reservoir pressure the height of oscillation and hence the intensity of pulsation are calculated. It is shown by a concrete example that 1) the oscillation of the liquid column in the pulsation tube and in the column is sinusoidal in all cases; 2) generation of a defined pulsation is restricted to the range between 0.3 and 3 Hz; 3) the amount of air needed for pulsation depends on the geometry of the column and in the intensity of pulsation. It can be optimized by appropriate selection of the diameter of the pulsation tube. (orig.) [de

Effects of pulse-to-pulse residual species on discharges in repetitively pulsed discharges through packed bed reactors

Science.gov (United States)

Kruszelnicki, Juliusz; Engeling, Kenneth W.; Foster, John E.; Kushner, Mark J.

2016-09-01

Atmospheric pressure dielectric barrier discharges (DBDs) sustained in packed bed reactors (PBRs) are being investigated for conversion of toxic and waste gases, and CO2 removal. These discharges are repetitively pulsed having varying flow rates and internal geometries, which results in species from the prior pulse still being in the discharge zone at the time the following discharge pulse occurs. A non-negligible residual plasma density remains, which effectively acts as preionization. This residual charge changes the discharge properties of subsequent pulses, and may impact important PBR properties such as chemical selectivity. Similarly, the residual neutral reactive species produced during earlier pulses will impact the reaction rates on subsequent pulses. We report on results of a computational investigation of a 2D PBR using the plasma hydrodynamics simulator nonPDPSIM. Results will be discussed for air flowing though an array of dielectric rods at atmospheric pressure. The effects of inter-pulse residual species on PBR discharges will be quantified. Means of controlling the presence of residual species in the reactor through gas flow rate, pulse repetition, pulse width and geometry will be described. Comparisons will be made to experiments. Work supported by US DOE Office of Fusion Energy Science and the National Science Foundation.

Effects of ultrasound on the proliferation and differentiation of cementoblast lineage cells

NARCIS (Netherlands)

Inubushi, T.; Tanaka, E.; Rego, E.B.; Kitagawa, M.; Kawazoe, A.; Ohta, A.; Okada, H.; Koolstra, J.H.; Miyauchi, M.; Takata, T.; Tanne, K.

2008-01-01

Background: The purpose of this study was to investigate the effects of low-intensity pulsed ultrasound (LIPUS) stimulation on the proliferation and differentiation of cementoblast lineage cells. Methods: An immortalized human periodontal ligament cell line (HPL) showing immature cementoblastic

Thermal Dynamics of Xanthene Dye in Polymer Matrix Excited by Double Pulse Laser Radiation

Science.gov (United States)

Samusev, Ilia; Borkunov, Rodion; Tsarkov, Maksim; Konstantinova, Elizaveta; Antipov, Yury; Demin, Maksim; Bryukhanov, Valery

2018-01-01

Double-pulse laser excitation of the eosin and silver nanoparticles embedded into polymer media is known to be a method of electronic-vibrational energy deactivation kinetic process information obtaining and polymer thermal dynamics investigation. We have studied the vibrational relaxation processes in dye molecules (eosin) and nanoparticles in polyvinyl alcohol after two time-shifted laser pulses with fast and delayed fluorescence kinetics study. In order to simulate thermal and photophysical processes caused by double photon excitation, we solved heat transfer and energy deactivation differential equations numerically. The simulation allowed us to obtain the value of heat conductivity coefficient of polymer matrix.

Characteristics of bipolar-pulse generator for intense pulsed heavy ion beam acceleration

International Nuclear Information System (INIS)

Igawa, K.; Tomita, T.; Kitamura, I.; Ito, H.; Masugata, K.

2006-01-01

Intense pulsed heavy ion beams are expected to be applied to the implantation technology for semiconductor materials. In the application it is very important to purify the ion beam. In order to improve the purity of an intense pulsed ion beams we have proposed a new type of pulsed ion beam accelerator named 'bipolar pulse accelerator (BPA)'. A prototype of the experimental system has been developed to perform proof of principle experiments of the accelerator. A bipolar pulse generator has been designed for the generation of the pulsed ion beam with the high purity via the bipolar pulse acceleration and the electrical characteristics of the generator were evaluated. The production of the bipolar pulse has been confirmed experimentally. (author)

Development of the pulse transformer for NLC klystron pulse modulator

International Nuclear Information System (INIS)

Akemoto, M.; Gold, S.; Koontz, R.; Krasnykh, A.

1997-05-01

We have studied a conventional pulse transformer for the NLC klystron pulse modulator. The transformer has been analyzed using a simplified lumped circuit model. It is found that a fast rise time requires low leakage inductance and low distributed capacitance and can be realized by reducing the number of secondary turns, but it produces larger pulse droop and core size. After making a tradeoff among these parameters carefully, a conventional pulse transformer with a rise time of 250ns and pulse droop of 3.6% has been designed and built. The transmission characteristics and pulse time-response were measured. The data were compared with the model. The agreement with the model was good when the measured values were used in the model simulation. The results of the high voltage tests are also presented

Optimal timing of pulse onset for language mapping with navigated repetitive transcranial magnetic stimulation.

Science.gov (United States)

Krieg, Sandro M; Tarapore, Phiroz E; Picht, Thomas; Tanigawa, Noriko; Houde, John; Sollmann, Nico; Meyer, Bernhard; Vajkoczy, Peter; Berger, Mitchel S; Ringel, Florian; Nagarajan, Srikantan

2014-10-15

Within the primary motor cortex, navigated transcranial magnetic stimulation (nTMS) has been shown to yield maps strongly correlated with those generated by direct cortical stimulation (DCS). However, the stimulation parameters for repetitive nTMS (rTMS)-based language mapping are still being refined. For this purpose, the present study compares two rTMS protocols, which differ in the timing of pulse train onset relative to picture presentation onset during object naming. Results were the correlated with DCS language mapping during awake surgery. Thirty-two patients with left-sided perisylvian tumors were examined by rTMS prior to awake surgery. Twenty patients underwent rTMS pulse trains starting at 300 ms after picture presentation onset (delayed TMS), whereas another 12 patients received rTMS pulse trains starting at the picture presentation onset (ONSET TMS). These rTMS results were then evaluated for correlation with intraoperative DCS results as gold standard in terms of differential consistencies in receiver operating characteristics (ROC) statistics. Logistic regression analysis by protocols and brain regions were conducted. Within and around Broca's area, there was no difference in sensitivity (onset TMS: 100%, delayed TMS: 100%), negative predictive value (NPV) (onset TMS: 100%, delayed TMS: 100%), and positive predictive value (PPV) (onset TMS: 55%, delayed TMS: 54%) between the two protocols compared to DCS. However, specificity differed significantly (onset TMS: 67%, delayed TMS: 28%). In contrast, for posterior language regions, such as supramarginal gyrus, angular gyrus, and posterior superior temporal gyrus, early pulse train onset stimulation showed greater specificity (onset TMS: 92%, delayed TMS: 20%), NPV (onset TMS: 92%, delayed TMS: 57%) and PPV (onset TMS: 75%, delayed TMS: 30%) with comparable sensitivity (onset TMS: 75%, delayed TMS: 70%). Logistic regression analysis also confirmed the greater fit of the predictions by rTMS that had the

Dynamic Characterization of Fiber Optical Chirped Pulse Amplification for Sub-ps Pulses

DEFF Research Database (Denmark)

Cristofori, Valentina; Lali-Dastjerdi, Zohreh; Rishøj, Lars Søgaard

2013-01-01

We investigate experimentally the propagation of sub-picosecond pulses in fiber optical parametric chirped pulse amplifiers, showing a significant broadening of the pulses from 450 fs up to 720 fs due to dispersion and self-phase modulation.......We investigate experimentally the propagation of sub-picosecond pulses in fiber optical parametric chirped pulse amplifiers, showing a significant broadening of the pulses from 450 fs up to 720 fs due to dispersion and self-phase modulation....

Petawatt pulsed-power accelerator

Science.gov (United States)

Stygar, William A.; Cuneo, Michael E.; Headley, Daniel I.; Ives, Harry C.; Ives, legal representative; Berry Cottrell; Leeper, Ramon J.; Mazarakis, Michael G.; Olson, Craig L.; Porter, John L.; Wagoner; Tim C.

2010-03-16

A petawatt pulsed-power accelerator can be driven by various types of electrical-pulse generators, including conventional Marx generators and linear-transformer drivers. The pulsed-power accelerator can be configured to drive an electrical load from one- or two-sides. Various types of loads can be driven; for example, the accelerator can be used to drive a high-current z-pinch load. When driven by slow-pulse generators (e.g., conventional Marx generators), the accelerator comprises an oil section comprising at least one pulse-generator level having a plurality of pulse generators; a water section comprising a pulse-forming circuit for each pulse generator and a level of monolithic triplate radial-transmission-line impedance transformers, that have variable impedance profiles, for each pulse-generator level; and a vacuum section comprising triplate magnetically insulated transmission lines that feed an electrical load. When driven by LTD generators or other fast-pulse generators, the need for the pulse-forming circuits in the water section can be eliminated.

Interaction of nucleic acids with electrically charged surfaces. VII. The effect of ionic strength of neutral medium on the conformation of dna adsorbed on the mercury electrode.

Science.gov (United States)

Brabec, V

1980-02-01

Triangular-wave direct current (d.c.) voltammetry at a hanging mercury drop electrode and phase-selective alternating current (a.c.) polarography at a dropping mercury electrode were used for the investigation of adsorption of double-helical (ds) DNA at mercury electrode surfaces from neutral solutions of 0.05-0.4 M HCOONH4. It was found for the potential region T (from -0.1 V up to ca. -1.0 V) that the height of voltammetric peaks of ds DNA is markedly influenced by the initial potential only at relatively low ionic strength (mu) (from 0.05 up to ca. 0.3). Also a decrease of differential capacity (measured by means of a.c. polarography) in the region T depended markedly on the electrode potential only at relatively low ionic strength. The following conclusions were made concerning the interaction of ds DNA with a mercury electrode charged to potentials of the region T in neutral medium of relatively low ionic strength mu potentials in the Vicinity of the zero charge potential a higher number of ds DNA segments can be opened, probably as a consequence of the strain which could act on the ds DNA molecule in the course of the segmental adsorption/desorption process.

Pulse transformer R and D for NLC klystron pulse modulator

International Nuclear Information System (INIS)

Akemoto, M.; Gold, S.; Krasnykh, A.; Koontz, R.

1997-07-01

The authors have studied a conventional pulse transformer for the NLC klystron pulse modulator. The transformer has been analyzed using a simplified lumped circuit model. It is found that a fast rise time requires low leakage inductance and low distributed capacitance and can be realized by reducing the number of secondary turns, but it produces larger pulse droop and requires a larger core size. After making a tradeoff among these parameters carefully, a conventional pulse transformer with a rise time of 250ns and a pulse droop of 3.6% has been designed and built. The transmission characteristics and pulse time-response were measured. The data were compared with the model. The agreement with the model was good when the measured values were used in the model simulation. The results of the high voltage tests using a klystron load are also presented

Random pulse generator

International Nuclear Information System (INIS)

Guo Ya'nan; Jin Dapeng; Zhao Dixin; Liu Zhen'an; Qiao Qiao; Chinese Academy of Sciences, Beijing

2007-01-01

Due to the randomness of radioactive decay and nuclear reaction, the signals from detectors are random in time. But normal pulse generator generates periodical pulses. To measure the performances of nuclear electronic devices under random inputs, a random generator is necessary. Types of random pulse generator are reviewed, 2 digital random pulse generators are introduced. (authors)

Fiber Optical Parametric Chirped Pulse Amplification of Sub-Picosecond Pulses

DEFF Research Database (Denmark)

Cristofori, Valentina; Lali-Dastjerdi, Zohreh; Da Ros, Francesco

2013-01-01

We demonstrate experimentally, for the first time to our knowledge, fiber optical parametric chirped pulse amplification of 400-fs pulses. The 400-fs signal is stretched, amplified by 26 dB and compressed back to 500 fs.......We demonstrate experimentally, for the first time to our knowledge, fiber optical parametric chirped pulse amplification of 400-fs pulses. The 400-fs signal is stretched, amplified by 26 dB and compressed back to 500 fs....

Pulse-to-pulse variations in accreting X-ray pulsars

Directory of Open Access Journals (Sweden)

Kretschmar Peter

2014-01-01

Full Text Available In most accreting X-ray pulsars, the periodic signal is very clear and easily shows up as soon as data covering sufficient pulse periods (a few ten are available. The mean pulse profile is often quite typical for a given source and with minor variations repeated and recognisable across observations done years or even decades apart. At the time scale of individual pulses, significant pulse-to-pulse variations are commonly observed. While at low energies some of these variations might be explained by absorption, in the hard X-rays they will reflect changes in the accretion and subsequent emission. The amount of these variations appears to be quite different between sources and contains information about the surrounding material as well ass possibly interactions at the magnetosphere. We investigate such variations for a sample of well-known sources.

Pulse to pulse klystron diagnosis system

International Nuclear Information System (INIS)

Nowak, J.; Davidson, V.; Genova, L.; Johnson, R.; Reagan, D.

1981-03-01

This report describes a system used to study the behavior of SLAC high powered klystrons operating with a twice normal pulse width of 5 μs. At present, up to eight of the klystrons installed along the accelerator can be operated with long pulses and monitored by this system. The report will also discuss some of the recent findings and investigations

Study of hydrodynamic and mass transfer parameters in pulsed sieve-plate columns

International Nuclear Information System (INIS)

Safdari, J.

2001-01-01

One of the most important liquid-liquid extractor in industry is pulsed column. The pulsed columns are generally classified into the following categories: 1-Pulsed perforated-plate column. 2- Pulsed packed column. The pulsed plate column is differential contactor with the application of mechanical energy and is used for a diverse range of processes. Probably its best known application has been in the nuclear fuel industry. The pulsed plate column consists of a cylindrical shell with settling zones at the top and the bottom of the column. The liquids are fed continuously to the column (flowing counter-currently) and are removed continuously from opposite ends of the column. In this work using a pilot pulsed plate column and two different chemical systems (toluene/acetone/water and n-butyl acetate/acetone/water) various experiments are carried out. In each experiment direction of mass transfer is from organic phase (dispersed phase) into aqueous phase (continuous phase) and the continuous phase is water. The main objects of this thesis are as follow: a- Investigation of effect of operating parameters on dispersed phase hold up, volumetric overall mass transfer coefficients based on dispersed and continuous phase, extraction efficiency, pressure drop of column and flooding velocities (maximum column capacities). Obtained results in this part show that if the calorimetric flow rate of aqueous phase or pulsation intensity increase, hold up, volumetric overall mass transfer coefficients based on both two phases and extraction efficiency will increase and flooding velocities will decrease. Also results show that if volumetric flow rate of organic phase increase, hold up, volumetric mass transfer coefficients based on both two phases and pressure drop will increase and extraction efficiency and flooding velocities will decrease. b- Investigation of effect of internal circulation inside drops in designing pulsed perforated-plate column

Efficient chirped-pulse amplification of sub-20 fs laser pulses

Energy Technology Data Exchange (ETDEWEB)

Matsuoka, Shinichi; Yamakawa, Koichi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

1998-03-01

We have developed a model for ultrabroadband and ultrashort pulse amplification including the effects of a pulse shaper for regenerative pulse shaping, gain narrowing and gain saturation in the amplifiers. Thin solid etalons are used to control both gain narrowing and gain saturation during amplification. This model has been used to design an optimized Ti:sapphire amplifier system for producing efficiently pulses of < 20-fs duration with approaching peak and average powers of 100 TW and 20 W. (author)

Patterns of digital volume pulse waveform and pulse transit time in ...

African Journals Online (AJOL)

In this study the digital volume pulse wave and the pulse transit time of the thumb and big toe were analyzed in young and older subjects some of whom were hypertensive. We aimed to study the components and patterns of the pulse waveform and the pulse transit time and how they might change. Material and Methods: ...

A 350 KV nanosecond pulse voltage generator with adjustable pulsed-width

International Nuclear Information System (INIS)

Wang, X.; Wang, M.; Chen, Y.Q.; Zeng, L.G.; Han, M.

2002-01-01

This paper presents a 350 kV nanosecond pulse voltage generator (NPVG). The voltage pulsed-width can be adjusted from 30 to 160 ns. The generator consists of: Marx generator, pulsed forming line (PFL), main switch and matched impedance. The output voltage of Marx generator is over than nU c (n- the stage number of Marx generator, U c -the charging voltage of capacitor). When the pulse forming line is terminated with an impedance that is over than the characteristic impedance of PFL, the higher voltage pulse was provided for the load

Pulse Shape Analysis and Discrimination for Silicon-Photomultipliers in Helium-4 Gas Scintillation Neutron Detector

Science.gov (United States)

Barker, Cathleen; Zhu, Ting; Rolison, Lucas; Kiff, Scott; Jordan, Kelly; Enqvist, Andreas

2018-01-01

Using natural helium (helium-4), the Arktis 180-bar pressurized gas scintillator is capable of detecting and distinguishing fast neutrons and gammas. The detector has a unique design of three optically separated segments in which 12 silicon-photomultiplier (SiPM) pairs are positioned equilaterally across the detector to allow for them to be fully immersed in the helium-4 gas volume; consequently, no additional optical interfaces are necessary. The SiPM signals were amplified, shaped, and readout by an analog board; a 250 MHz, 14-bit digitizer was used to examine the output pulses from each SiPMpair channel. The SiPM over-voltage had to be adjusted in order to reduce pulse clipping and negative overshoot, which was observed for events with high scintillation production. Pulse shaped discrimination (PSD) was conducted by evaluating three different parameters: time over threshold (TOT), pulse amplitude, and pulse integral. In order to differentiate high and low energy events, a 30ns gate window was implemented to group pulses from two SiPM channels or more for the calculation of TOT. It was demonstrated that pulses from a single SiPM channel within the 30ns window corresponded to low-energy gamma events while groups of pulses from two-channels or more were most likely neutron events. Due to gamma pulses having lower pulse amplitude, the percentage of measured gamma also depends on the threshold value in TOT calculations. Similarly, the threshold values were varied for the optimal PSD methods of using pulse amplitude and pulse area parameters. Helium-4 detectors equipped with SiPMs are excellent for in-the-field radiation measurement of nuclear spent fuel casks. With optimized PSD methods, the goal of developing a fuel cask content monitoring and inspection system based on these helium-4 detectors will be achieved.

Differential pulse voltammetric determination of nanomolar concentrations of antiviral drug acyclovir at polymer film modified glassy carbon electrode

Energy Technology Data Exchange (ETDEWEB)

Dorraji, Parisa S.; Jalali, Fahimeh, E-mail: fjalali@razi.ac.ir

2016-04-01

An electrochemical sensor for the sensitive detection of acyclovir was developed by the electropolymerization of Eriochrome black T at a pretreated glassy carbon electrode. The surface morphology of the modified electrode was characterized by field emission scanning electron microscopy. Under the optimized conditions, a significant electrochemical improvement was observed toward the electrooxidation of acyclovir on the modified electrode surface relative to the unmodified electrode. The detection limit of 12 nM and two linear calibration ranges of 0.03–0.3 μM and 0.3–1.5 μM were obtained for acyclovir determination using a differential pulse voltammetric method in acetate buffer (0.1 M, pH 4.0). Real sample studies were carried out in human blood serum and pharmaceutical formulations, which offered good recovery (98–102%). The electrode showed excellent reproducibility, selectivity and antifouling effects. - Graphical abstract: Eriochrome black T (EBT) was electropolymerized at the surface of a pretreated glassy carbon electrode. The modified electrode enhanced the oxidation current of acyclovir, significantly. The sensor was used in the determination of acyclovir in human blood serum samples and pharmaceutical dosages. - Highlights: • Construction of a voltammetric sensor for acyclovir is described. • Eriochrome black T was electropolymerized at the electrode surface. • The sensor improved the sensitivity of the electrode for monitoring acyclovir. • The recoveries and standard deviations were acceptable in spiked human blood serum. • The proposed sensor had good lifetime to be used in biological matrices.

Adsorptive stripping differential pulse voltammetric determination of venlafaxine and desvenlafaxine employing Nafion-carbon nanotube composite glassy carbon electrode

Energy Technology Data Exchange (ETDEWEB)

Sanghavi, Bankim J. [Department of Chemistry, University of Mumbai, Vidyanagari, Santacruz (East), Mumbai 400 098, Maharashtra (India); Srivastava, Ashwini K., E-mail: aksrivastava@chem.mu.ac.i [Department of Chemistry, University of Mumbai, Vidyanagari, Santacruz (East), Mumbai 400 098, Maharashtra (India)

2011-04-15

A Nafion-carbon nanotube-modified glassy carbon electrode (NAF-CNT-GCE) was developed for the determination of venlafaxine (VF) and desvenlafaxine (DVF). The electrochemical behavior of both these molecules was investigated employing cyclic voltammetry (CV), chronocoulometry (CC), electrochemical impedance spectroscopy (EIS) and adsorptive stripping differential pulse voltammetry (AdSDPV). The surface morphology of the electrodes has been studied by means of scanning electron microscopy (SEM). These studies revealed that the oxidation of VF and DVF is facilitated at NAF-CNT-GCE. After optimization of analytical conditions employing this electrode at pH 7.0 in Britton-Robinson buffer (0.05 M) for VF and pH 5.0 in acetate buffer (0.1 M) for DVF, the peak currents for both the molecules were found to vary linearly with their concentrations in the range of 3.81 x 10{sup -8}-6.22 x 10{sup -5} M for VF and 5.33 x 10{sup -8}-3.58 x 10{sup -5} M for DVF. The detection limits (S/N = 3) of 1.24 x 10{sup -8} and 2.11 x 10{sup -8} M were obtained for VF and DVF, respectively, using AdSDPV. The prepared modified electrode showed several advantages, such as simple preparation method, high sensitivity, very low detection limits and excellent reproducibility. The proposed method was employed for the determination of VF and DVF in pharmaceutical formulations, urine and blood serum samples.

Differential pulse voltammetric determination of nanomolar concentrations of antiviral drug acyclovir at polymer film modified glassy carbon electrode

International Nuclear Information System (INIS)

Dorraji, Parisa S.; Jalali, Fahimeh

2016-01-01

An electrochemical sensor for the sensitive detection of acyclovir was developed by the electropolymerization of Eriochrome black T at a pretreated glassy carbon electrode. The surface morphology of the modified electrode was characterized by field emission scanning electron microscopy. Under the optimized conditions, a significant electrochemical improvement was observed toward the electrooxidation of acyclovir on the modified electrode surface relative to the unmodified electrode. The detection limit of 12 nM and two linear calibration ranges of 0.03–0.3 μM and 0.3–1.5 μM were obtained for acyclovir determination using a differential pulse voltammetric method in acetate buffer (0.1 M, pH 4.0). Real sample studies were carried out in human blood serum and pharmaceutical formulations, which offered good recovery (98–102%). The electrode showed excellent reproducibility, selectivity and antifouling effects. - Graphical abstract: Eriochrome black T (EBT) was electropolymerized at the surface of a pretreated glassy carbon electrode. The modified electrode enhanced the oxidation current of acyclovir, significantly. The sensor was used in the determination of acyclovir in human blood serum samples and pharmaceutical dosages. - Highlights: • Construction of a voltammetric sensor for acyclovir is described. • Eriochrome black T was electropolymerized at the electrode surface. • The sensor improved the sensitivity of the electrode for monitoring acyclovir. • The recoveries and standard deviations were acceptable in spiked human blood serum. • The proposed sensor had good lifetime to be used in biological matrices.

Optical pulse compression

International Nuclear Information System (INIS)

Glass, A.J.

1975-01-01

The interest in using large lasers to achieve a very short and intense pulse for generating fusion plasma has provided a strong impetus to reexamine the possibilities of optical pulse compression at high energy. Pulse compression allows one to generate pulses of long duration (minimizing damage problems) and subsequently compress optical pulses to achieve the short pulse duration required for specific applications. The ideal device for carrying out this program has not been developed. Of the two approaches considered, the Gires--Tournois approach is limited by the fact that the bandwidth and compression are intimately related, so that the group delay dispersion times the square of the bandwidth is about unity for all simple Gires--Tournois interferometers. The Treacy grating pair does not suffer from this limitation, but is inefficient because diffraction generally occurs in several orders and is limited by the problem of optical damage to the grating surfaces themselves. Nonlinear and parametric processes were explored. Some pulse compression was achieved by these techniques; however, they are generally difficult to control and are not very efficient. (U.S.)

Crystallization kinetics of GeTe phase-change thin films grown by pulsed laser deposition

Science.gov (United States)

Sun, Xinxing; Thelander, Erik; Gerlach, Jürgen W.; Decker, Ulrich; Rauschenbach, Bernd

2015-07-01

Pulsed laser deposition was employed to the growth of GeTe thin films on Silicon substrates. X-ray diffraction measurements reveal that the critical crystallization temperature lies between 220 and 240 °C. Differential scanning calorimetry was used to investigate the crystallization kinetics of the as-deposited films, determining the activation energy to be 3.14 eV. Optical reflectivity and in situ resistance measurements exhibited a high reflectivity contrast of ~21% and 3-4 orders of magnitude drop in resistivity of the films upon crystallization. The results show that pulsed laser deposited GeTe films can be a promising candidate for phase-change applications.

Crystallization kinetics of GeTe phase-change thin films grown by pulsed laser deposition

International Nuclear Information System (INIS)

Sun, Xinxing; Thelander, Erik; Gerlach, Jürgen W; Decker, Ulrich; Rauschenbach, Bernd

2015-01-01

Pulsed laser deposition was employed to the growth of GeTe thin films on Silicon substrates. X-ray diffraction measurements reveal that the critical crystallization temperature lies between 220 and 240 °C. Differential scanning calorimetry was used to investigate the crystallization kinetics of the as-deposited films, determining the activation energy to be 3.14 eV. Optical reflectivity and in situ resistance measurements exhibited a high reflectivity contrast of ∼21% and 3–4 orders of magnitude drop in resistivity of the films upon crystallization. The results show that pulsed laser deposited GeTe films can be a promising candidate for phase-change applications. (paper)

Pulse induction heating

Energy Technology Data Exchange (ETDEWEB)

Vasiliev, A S; Kachanov, B Y; Kogan, B V

1993-12-31

Induction heating and three types of pulse processes were studied. It was found that in pulse processes the frequency and pulse duration of heat treatments do not remain constant. High frequency pulse heat treatments can be used on sprayed coatings; such treatments will result in stronger surfaces with no cracks. For induction hardening, the rate of specific power was 1 to 1.5 kW/sq.cm, for forging it was 0.2 to 0.3 kW/sq.cm and for melting it was 0.05 to 0.1 kW/sq.cm. The application of pulse heating will result in higher rates of specific power.

Pulse-shaping mechanism in colliding-pulse mode-locked laser diodes

DEFF Research Database (Denmark)

Bischoff, Svend; Sørensen, Mads Peter; Mørk, J.

1995-01-01

The large signal dynamics of passively colliding pulse mode-locked laser diodes is studied. We derive a model which explains modelocking via the interplay of gain and loss dynamics; no bandwidth limiting element is necessary for pulse formation. It is found necessary to have both fast and slow...... absorber dynamics to achieve mode-locking. Significant chirp is predicted for pulses emitted from long lasers, in agreement with experiment. The pulse width shows a strong dependence on both cavity and saturable absorber length. (C) 1995 American Institute of Physics....

S100 lathe bed pulse generator applied to pulsed nuclear magnetic resonance

International Nuclear Information System (INIS)

Cernicchiaro, G.R.C.; Rudge, M.G.; Albuquerque, M.P.

1989-01-01

The project and construction of four channel pulse generator in the S100 standard plate and its control software for microcomputer are described. The microcomputer has total control on the pulse generator, which has seven programable parameters, defining the position of four pulses and the width for the three first ones. This pulse generator is controlled by a software developed in c language, and is used in pulsed nuclear magnetic resonance experiences. (M.C.K.) [pt

Differential Polarization Nonlinear Optical Microscopy with Adaptive Optics Controlled Multiplexed Beams

Directory of Open Access Journals (Sweden)

Virginijus Barzda

2013-09-01

Full Text Available Differential polarization nonlinear optical microscopy has the potential to become an indispensable tool for structural investigations of ordered biological assemblies and microcrystalline aggregates. Their microscopic organization can be probed through fast and sensitive measurements of nonlinear optical signal anisotropy, which can be achieved with microscopic spatial resolution by using time-multiplexed pulsed laser beams with perpendicular polarization orientations and photon-counting detection electronics for signal demultiplexing. In addition, deformable membrane mirrors can be used to correct for optical aberrations in the microscope and simultaneously optimize beam overlap using a genetic algorithm. The beam overlap can be achieved with better accuracy than diffraction limited point-spread function, which allows to perform polarization-resolved measurements on the pixel-by-pixel basis. We describe a newly developed differential polarization microscope and present applications of the differential microscopy technique for structural studies of collagen and cellulose. Both, second harmonic generation, and fluorescence-detected nonlinear absorption anisotropy are used in these investigations. It is shown that the orientation and structural properties of the fibers in biological tissue can be deduced and that the orientation of fluorescent molecules (Congo Red, which label the fibers, can be determined. Differential polarization microscopy sidesteps common issues such as photobleaching and sample movement. Due to tens of megahertz alternating polarization of excitation pulses fast data acquisition can be conveniently applied to measure changes in the nonlinear signal anisotropy in dynamically changing in vivo structures.

Terahertz pulse imaging in reflection geometry of human skin cancer and skin tissue

International Nuclear Information System (INIS)

Woodward, Ruth M; Cole, Bryan E; Wallace, Vincent P; Pye, Richard J; Arnone, Donald D; Linfield, Edmund H; Pepper, Michael

2002-01-01

We demonstrate the application of terahertz pulse imaging (TPI) in reflection geometry for the study of skin tissue and related cancers both in vitro and in vivo. The sensitivity of terahertz radiation to polar molecules, such as water, makes TPI suitable for studying the hydration levels in the skin and the determination of the lateral spread of skin cancer pre-operatively. By studying the terahertz pulse shape in the time domain we have been able to differentiate between diseased and normal tissue for the study of basal cell carcinoma (BCC). Basal cell carcinoma has shown a positive terahertz contrast, and inflammation and scar tissue a negative terahertz contrast compared to normal tissue. In vivo measurements on the stratum corneum have enabled visualization of the stratum corneum-epidermis interface and the study of skin hydration levels. These results demonstrate the potential of terahertz pulse imaging for the study of skin tissue and its related disorders, both in vitro and in vivo

High-Wattage Pulsed Irradiation of Linearly Polarized Near-Infrared Light to Stellate Ganglion Area for Burning Mouth Syndrome

Directory of Open Access Journals (Sweden)

Yukihiro Momota

2014-01-01

Full Text Available The purpose of this study was to apply high-wattage pulsed irradiation of linearly polarized near-infrared light to the stellate ganglion area for burning mouth syndrome (BMS and to assess the efficacy of the stellate ganglion area irradiation (SGR on BMS using differential time-/frequency-domain parameters (D parameters. Three patients with BMS received high-wattage pulsed SGR; the response to SGR was evaluated by visual analogue scale (VAS representing the intensity of glossalgia and D parameters used in heart rate variability analysis. High-wattage pulsed SGR significantly decreased the mean value of VAS in all cases without any adverse event such as thermal injury. D parameters mostly correlated with clinical condition of BMS. High-wattage pulsed SGR was safe and effective for the treatment of BMS; D parameters are useful for assessing efficacy of SGR on BMS.

Laser pulse stacking method

Science.gov (United States)

Moses, E.I.

1992-12-01

A laser pulse stacking method is disclosed. A problem with the prior art has been the generation of a series of laser beam pulses where the outer and inner regions of the beams are generated so as to form radially non-synchronous pulses. Such pulses thus have a non-uniform cross-sectional area with respect to the outer and inner edges of the pulses. The present invention provides a solution by combining the temporally non-uniform pulses in a stacking effect to thus provide a more uniform temporal synchronism over the beam diameter. 2 figs.

Controllable pulse parameter transcranial magnetic stimulator with enhanced circuit topology and pulse shaping

Science.gov (United States)

Peterchev, Angel V.; DʼOstilio, Kevin; Rothwell, John C.; Murphy, David L.

2014-10-01

Objective. This work aims at flexible and practical pulse parameter control in transcranial magnetic stimulation (TMS), which is currently very limited in commercial devices. Approach. We present a third generation controllable pulse parameter device (cTMS3) that uses a novel circuit topology with two energy-storage capacitors. It incorporates several implementation and functionality advantages over conventional TMS devices and other devices with advanced pulse shape control. cTMS3 generates lower internal voltage differences and is implemented with transistors with a lower voltage rating than prior cTMS devices. Main results. cTMS3 provides more flexible pulse shaping since the circuit topology allows four coil-voltage levels during a pulse, including approximately zero voltage. The near-zero coil voltage enables snubbing of the ringing at the end of the pulse without the need for a separate active snubber circuit. cTMS3 can generate powerful rapid pulse sequences (\\lt 10 ms inter pulse interval) by increasing the width of each subsequent pulse and utilizing the large capacitor energy storage, allowing the implementation of paradigms such as paired-pulse and quadripulse TMS with a single pulse generation circuit. cTMS3 can also generate theta (50 Hz) burst stimulation with predominantly unidirectional electric field pulses. The cTMS3 device functionality and output strength are illustrated with electrical output measurements as well as a study of the effect of pulse width and polarity on the active motor threshold in ten healthy volunteers. Significance. The cTMS3 features could extend the utility of TMS as a research, diagnostic, and therapeutic tool.

Non-destructive characterization using pulsed fast-thermal neutrons

International Nuclear Information System (INIS)

Womble, P.C.

1995-01-01

Explosives, illicit drugs, and other contraband materials contain various chemical elements in quantities and ratios that differentiate them from each other and from innocuous substances. Furthermore, the major chemical elements in coal can provide information about various parameters of importance to the coal industry. In both examples, the non-destructive identification of chemical elements can be performed using pulsed fast-thermal neutrons that, through nuclear reactions, excite the nuclei of the various elements. This technique is being currently developed for the dismantling of nuclear weapons classified as trainers, and for the on-line coal bulk analysis. (orig.)

Composition and performance of thin film CdSe electrodeposited from selenosulfite solution

International Nuclear Information System (INIS)

Szabo, J.P.; Simms, D.; Cocivera, M.

1985-01-01

Cathodic electrodeposition of thin film CdSe from aqueous selenosulfite solution has been studied as function of solution composition and electrode potential. The Cd/Se ratio has been analyzed using polarography and Rutherford backscattering spectroscopy. Polarography gives a compostion averaged over the whole film (2cm 2 ) while RBS gives local surface composition (1 mm 2 ). The average Cd/Se ratio is 1.1, but some variation was found to occur across the surface of film (0.82 to 1.2)

Pulsed electron-beam annealing of selenium-implanted gallium arsenide

International Nuclear Information System (INIS)

Inada, T.; Tokunaga, K.; Taka, S.

1979-01-01

Electrical properties of selenium-implanted gallium arsenide annealed by a single shot of high-power pulsed electron beams have been investigated by differential Hall-effect and sheet-resistivity measurements. It has been shown that higher electrical activation of implanted selenium can be obtained after electron-beam annealing at an incident energy density of 1.2 J/cm 2 , independent of heating of GaAs substrate during implantation. Measured carrier concentrations exhibit uniformly distributed profiles having carrier concentrations of 2--3 x 10 19 /cm 3 , which is difficult to realize by conventional thermal annealing

Differential pulse cathodic stripping voltammetric determination of uranium with arsenazo-III at the hanging mercury dropping electrode

Energy Technology Data Exchange (ETDEWEB)

Kadi, M.W.; El-Shahawi, M.S. [Chemistry Dept., King Abdulaziz Univ., Jeddah (Saudi Arabia)

2009-07-01

An accurate, inexpensive and less laborious controlled adsorptive accumulation of uranium(VI)-arsenazo-III on a hanging mercury drop electrode (HMDE) has been developed for uranium(VI) determination. The method is based upon the collection of uranium(VI)-arsenazo-III complex at pH 5-6 at the HMDE and subsequent direct stripping measurement of the element in the nanomolar concentration level. The cathodic peak current (i{sub p,c}) of the adsorbed complex ions of uranium(VI) was measured at -0.35 V vs. Ag/AgCl reference electrode by differential pulse cathodic stripping voltammetry (DP-CSV), proceeded by an accumulation period of 150s2.5 in Britton-Robinson buffer of pH 5. The plot of the resulting i{sub p,c} vs. uranium(VI) concentration was linear in the range 2.1 x 10{sup -9} to 9.60 x 10{sup -7} mol L{sup -1} uranium(VI) and tended to level off at above 9.6 x 10{sup -7} mol L{sup -1}. The limits of detection and quantification of uranium(VI) were found to be 4.7 x 10{sup -10} and 1.5 x 10{sup -9} mol L{sup -1}, respectively. A relative standard deviation of {+-}2.39% (n = 5) at 8.5 x 10{sup -7} mol L{sup -1} uranium(VI) was obtained. The method was validated by comparing the results with that obtained by ICP-MS method with RSD less than {+-}3.3%. The method was applied successfully for the analysis of uranium in certified reference material (IAEA soil-7), and in phosphate fertilizers. (orig.)

Modelling multi-pulse population dynamics from ultrafast spectroscopy.

Directory of Open Access Journals (Sweden)

Luuk J G W van Wilderen

2011-03-01

Full Text Available Current advanced laser, optics and electronics technology allows sensitive recording of molecular dynamics, from single resonance to multi-colour and multi-pulse experiments. Extracting the occurring (bio- physical relevant pathways via global analysis of experimental data requires a systematic investigation of connectivity schemes. Here we present a Matlab-based toolbox for this purpose. The toolbox has a graphical user interface which facilitates the application of different reaction models to the data to generate the coupled differential equations. Any time-dependent dataset can be analysed to extract time-independent correlations of the observables by using gradient or direct search methods. Specific capabilities (i.e. chirp and instrument response function for the analysis of ultrafast pump-probe spectroscopic data are included. The inclusion of an extra pulse that interacts with a transient phase can help to disentangle complex interdependent pathways. The modelling of pathways is therefore extended by new theory (which is included in the toolbox that describes the finite bleach (orientation effect of single and multiple intense polarised femtosecond pulses on an ensemble of randomly oriented particles in the presence of population decay. For instance, the generally assumed flat-top multimode beam profile is adapted to a more realistic Gaussian shape, exposing the need for several corrections for accurate anisotropy measurements. In addition, the (selective excitation (photoselection and anisotropy of populations that interact with single or multiple intense polarised laser pulses is demonstrated as function of power density and beam profile. Using example values of real world experiments it is calculated to what extent this effectively orients the ensemble of particles. Finally, the implementation includes the interaction with multiple pulses in addition to depth averaging in optically dense samples. In summary, we show that mathematical

Modelling multi-pulse population dynamics from ultrafast spectroscopy.

Science.gov (United States)

van Wilderen, Luuk J G W; Lincoln, Craig N; van Thor, Jasper J

2011-03-21

Current advanced laser, optics and electronics technology allows sensitive recording of molecular dynamics, from single resonance to multi-colour and multi-pulse experiments. Extracting the occurring (bio-) physical relevant pathways via global analysis of experimental data requires a systematic investigation of connectivity schemes. Here we present a Matlab-based toolbox for this purpose. The toolbox has a graphical user interface which facilitates the application of different reaction models to the data to generate the coupled differential equations. Any time-dependent dataset can be analysed to extract time-independent correlations of the observables by using gradient or direct search methods. Specific capabilities (i.e. chirp and instrument response function) for the analysis of ultrafast pump-probe spectroscopic data are included. The inclusion of an extra pulse that interacts with a transient phase can help to disentangle complex interdependent pathways. The modelling of pathways is therefore extended by new theory (which is included in the toolbox) that describes the finite bleach (orientation) effect of single and multiple intense polarised femtosecond pulses on an ensemble of randomly oriented particles in the presence of population decay. For instance, the generally assumed flat-top multimode beam profile is adapted to a more realistic Gaussian shape, exposing the need for several corrections for accurate anisotropy measurements. In addition, the (selective) excitation (photoselection) and anisotropy of populations that interact with single or multiple intense polarised laser pulses is demonstrated as function of power density and beam profile. Using example values of real world experiments it is calculated to what extent this effectively orients the ensemble of particles. Finally, the implementation includes the interaction with multiple pulses in addition to depth averaging in optically dense samples. In summary, we show that mathematical modelling is

RF Pulsed Heating

Energy Technology Data Exchange (ETDEWEB)

Pritzkau, David P.

2002-01-03

RF pulsed heating is a process by which a metal is heated from magnetic fields on its surface due to high-power pulsed RF. When the thermal stresses induced are larger than the elastic limit, microcracks and surface roughening will occur due to cyclic fatigue. Pulsed heating limits the maximum magnetic field on the surface and through it the maximum achievable accelerating gradient in a normal conducting accelerator structure. An experiment using circularly cylindrical cavities operating in the TE{sub 011} mode at a resonant frequency of 11.424 GHz is designed to study pulsed heating on OFE copper, a material commonly used in normal conducting accelerator structures. The high-power pulsed RF is supplied by an X-band klystron capable of outputting 50 MW, 1.5 {micro}s pulses. The test pieces of the cavity are designed to be removable to allow testing of different materials with different surface preparations. A diagnostic tool is developed to measure the temperature rise in the cavity utilizing the dynamic Q change of the resonant mode due to heating. The diagnostic consists of simultaneously exciting a TE{sub 012} mode to steady-state in the cavity at 18 GHz and measuring the change in reflected power as the cavity is heated from high-power pulsed RF. Two experimental runs were completed. One run was executed at a calculated temperature rise of 120 K for 56 x 10{sup 6} pulses. The second run was executed at a calculated temperature rise of 82 K for 86 x 10{sup 6} pulses. Scanning electron microscope pictures show extensive damage occurring in the region of maximum temperature rise on the surface of the test pieces.

Pulsed eddy current inspection system for nondestructive examination of irradiated fuel rods

International Nuclear Information System (INIS)

Yancey, M.E.

1979-01-01

An inspection system has been developed for nondestructive examination of irradiated fuel rods utilizing pulsed eddy current techniques. The system employs an encircling type pulsed eddy current transducer capable of sensing small defects located on both the inner and outer diameter fuel rod surfaces during a single scan. Pulsed eddy current point probes are used to provide fuel rod wall thikness data and an indication of radial defect location. Two linear variable differential transformers are used to provide information on fuel rod diameter variation. A microprocessor based control system is used to automatically scan fuel rods up to 4.06 meters in length at predetermined radial locations. Defects as small as 0.005 cm deep by 0.254 cm long by 0.005 cm wide have been detected on outside diameter surfaces of a 1.43 cm outside diameter fuel rod cladding with a 0.094 cm wall thickness and 0.010 cm deep by 0.254 cm long by 0.005 cm wide on the inside diameter surface

Optimal pulse fishing policy in stage-structured models with birth pulses

International Nuclear Information System (INIS)

Gao Shujing; Chen Lansun; Sun Lihua

2005-01-01

In this paper, we propose exploited models with stage structure for the dynamics in a fish population for which periodic birth pulse and pulse fishing occur at different fixed time. Using the stroboscopic map, we obtain an exact cycle of system, and obtain the threshold conditions for its stability. Bifurcation diagrams are constructed with the birth rate (or pulse fishing time or harvesting effort) as the bifurcation parameter, and these are observed to display complex dynamic behaviors, including chaotic bands with period windows, period-doubling, multi-period-halving and incomplete period-doubling bifurcation, pitch-fork and tangent bifurcation, non-unique dynamics (meaning that several attractors or attractor and chaos coexist) and attractor crisis. This suggests that birth pulse and pulse fishing provide a natural period or cyclicity that make the dynamical behaviors more complex. Moreover, we show that the pulse fishing has a strong impact on the persistence of the fish population, on the volume of mature fish stock and on the maximum annual-sustainable yield. An interesting result is obtained that, after the birth pulse, the population can sustain much higher harvesting effort if the mature fish is removed as early as possible

Versatile pulse programmer for pulsed nuclear magnetic resonance spectroscopy

International Nuclear Information System (INIS)

Adduci, D.J.

1979-05-01

A description of the sequence of events and the decisions leading to the design of a versatile pulse programmer for pulsed NMR are presented. Background and application information is discussed in order that the reader might better understand the role of the pulse programmer in a NMR spectrometer. Various other design approaches are presented as a basis for comparison. Specifications for this design are proposed, the hardware implementation of the specifications is discussed, and the software operating system is presented

Versatile pulse programmer for pulsed nuclear magnetic resonance spectroscopy

Energy Technology Data Exchange (ETDEWEB)

Adduci, D.J.

1979-05-01

A description of the sequence of events and the decisions leading to the design of a versatile pulse programmer for pulsed NMR are presented. Background and application information is discussed in order that the reader might better understand the role of the pulse programmer in a NMR spectrometer. Various other design approaches are presented as a basis for comparison. Specifications for this design are proposed, the hardware implementation of the specifications is discussed, and the software operating system is presented.

A compact bipolar pulse-forming network-Marx generator based on pulse transformers.

Science.gov (United States)

Zhang, Huibo; Yang, Jianhua; Lin, Jiajin; Yang, Xiao

2013-11-01

A compact bipolar pulse-forming network (PFN)-Marx generator based on pulse transformers is presented in this paper. The high-voltage generator consisted of two sets of pulse transformers, 6 stages of PFNs with ceramic capacitors, a switch unit, and a matched load. The design is characterized by the bipolar pulse charging scheme and the compact structure of the PFN-Marx. The scheme of bipolar charging by pulse transformers increased the withstand voltage of the ceramic capacitors in the PFNs and decreased the number of the gas gap switches. The compact structure of the PFN-Marx was aimed at reducing the parasitic inductance in the generator. When the charging voltage on the PFNs was 35 kV, the matched resistive load of 48 Ω could deliver a high-voltage pulse with an amplitude of 100 kV. The full width at half maximum of the load pulse was 173 ns, and its rise time was less than 15 ns.

Development of bipolar pulse accelerator for intense pulsed ion beam acceleration

International Nuclear Information System (INIS)

Fujioka, Y.; Mitsui, C.; Kitamura, I.; Takahashi, T.; Masugata, K.; Tanoue, H.; Arai, K.

2003-01-01

To improve the purity of an intense pulsed ion beams a new type of pulsed ion beam accelerator named 'bipolar pulse accelerator (BPA)' was proposed. In the accelerator purity of the beam is expected. To confirm the principle of the accelerator experimental system was developed. The system utilizes B y type magnetically insulated acceleration gap and operated with single polar negative pulse. A coaxial gas puff plasma gun placed in the grounded anode was used as an ion source, and source plasma (nitrogen) of current density approx. = 25 A/cm 2 , duration approx. = 1.5 μs was injected into the acceleration gap. The ions are successfully accelerated from the grounded anode to the drift tube by applying negative pulse of voltage 180 kV, duration 60 ns to the drift tube. Pulsed ion beam of current density approx. = 40 A/cm 2 , duration approx. 60 ns was obtained at 42 mm downstream from the anode surface. (author)

Producing High Intense Attosecond Pulse Train by Interaction of Three-Color Pulse and Overdense Plasma

Science.gov (United States)

Salehi, M.; Mirzanejad, S.

2017-05-01

Amplifying the attosecond pulse by the chirp pulse amplification method is impossible. Furthermore, the intensity of attosecond pulse is low in the interaction of laser pulse and underdense plasma. This motivates us to propose using a multi-color pulse to produce the high intense attosecond pulse. In the present study, the relativistic interaction of a three-color linearly-polarized laser-pulse with highly overdense plasma is studied. We show that the combination of {{ω }}1, {{ω }}2 and {{ω }}3 frequencies decreases the instance full width at half maximum reflected attosecond pulse train from the overdense plasma surface. Moreover, we show that the three-color pulse increases the intensity of generated harmonics, which is explained by the relativistic oscillating mirror model. The obtained results demonstrate that if the three-color laser pulse interacts with overdense plasma, it will enhance two orders of magnitude of intensity of ultra short attosecond pulses in comparison with monochromatic pulse.

Hydraulic pressure pulses with elastic and plastic structural flexibility: test and analysis (LWBR Development Program)

International Nuclear Information System (INIS)

Schwirian, R.E.

1978-03-01

Pressure pulse tests were conducted with a flexible test section in a test vessel filled with room temperature water. The pressure pulses were generated with a drop hammer and piston pulse generator and were of a sufficient magnitude to cause plastic deformation of the test section. Because of the strong pressure relief effect of the deforming test section, pressure pulse magnitudes were below 265 psig in magnitude and had durations of 50 to 55 msecs. Calculations performed with the FLASH-35 bi-linear hysteresis model of structural deformation show good agreement with experiment. In particular, FLASH 35 adequately predicts the decrease in peak pressure and the increase in pulse duration due to elastic and plastic deformation of the test section. Predictions of flexible member motion are good, but are less satisfactory than the pressure pulse results due to uncertainties in the values of yield point and beyond yield stiffness used to model the various flexible members. Coupled with this is a strong sensitivity of the FLASH 35 predictions to the values of yield point and beyond yield stiffness chosen for the various flexible members. The test data versus calculation comparisons presented here provide preliminary qualification for FLASH 35 calculations of transient hydraulic pressures and pressure differentials in the presence of flexible structural members which deform both elastically and plastically

Long-pulse applications of pulse-forming lines for high-power linac application

International Nuclear Information System (INIS)

Hoeberling, R.F.; Tallerico, P.J.

1981-01-01

The ever present demands for high efficiency in the RF power stations for particle accelerators have caused increased interest in longer RF pulses (ten's of microseconds) for linacs such as the Pion Generator for Medical Irradiation (PIGMI) and Free Electron Laser (FEL). For either RF power station, a fundamental decision is whether to use a modulating anode/hard-tube driver or pulsed cathode/line-type pulser configuration. The choices in the extremes of low power for very long pulses or for very-high-power, short pulses are, respectively, a modulated anode/hard tube modulator and pulsed cathode/pulse forming line. However, the demarcation between these two extremes is not clearcut. The criteria (cost, flexibility performance, reliability, efficiency) that resulted in the RF station definition of these two specific systems will be described

The contents of sesamol and related lignans in sesame, tahina and halva as determined by a newly developed polarographic and stripping voltammetric analysis

Directory of Open Access Journals (Sweden)

2009-06-01

Full Text Available The contents of antioxidant lignans (Sesamol in sesame, commercial formulations of tahina and halva, which are processed tahina foods, were determined by Differential Pulse Polarography (DPP with a capillary hanging mercury drop electrode (HMDE. A platinum wire was used as the counter electrode and Ag/AgCl was the reference electrode. Samples have been analyzed by standard addition procedures and found to be quantitative (p2=0.9999 (pSe determinó el contenido del lignano antioxidante (Sesamol en sésamo, formulaciones comerciales de tahina y halva, que es el producto procesado de tahina, por polarografía de pulsos diferencial (DPP con un capilar conteniendo un electrodo de gota de mercurio (HMDE. Un hilo de platino fué usado como el electrodo contador y Ag/AgCl como electrodo de referencia. Las muestras fueron analizadas por procedimientos de adición de patrones y se encontró que wl procedimiento era cuantitativo (p2= 0.9999 (p< 0.01. El método polarográfico propuesto (DPP es un método rápido y reproducible para la determinación simultánea de lignanos fenólicos en sésamo y otros productos alimentarios que contienen sésamo. Éste proporciona una detección cuantitativa adecuada y sensible de este compuesto nutraceútico en alimentos comerciales.

Electroanalytical procedure for the determination of methylparathion in soil suspensions and its application for sorption studies with Brazilian soils

Directory of Open Access Journals (Sweden)

Castanho Giuliane M.

2003-01-01

Full Text Available The differential pulse polarography technique was used to establish an electroanalytical procedure for the determination of the organophosphorous insecticide methyl parathion (O,O-dimethyl O-(4-nitrophenyl phosphorothioate in soil samples. Three reduction peaks were observed in mercury electrodes as a function of the solution pH. The more cathodic peak (Ep= -0.55V, only observed for pH values higher than 5.0, was chosen for the analytical determinations. The limit of detection was 1.93x10-8 mol L-1 for pure water and about 8x10-8 mol L-1 for soil suspensions with a scan rate of 2 mV s-1 and a pH of 6.75. The electroanalytical procedure developed was applied for the determination of sorption isotherms of methylparathion on 3 soils from São Paulo State, Brazil, at different pH and diverse amounts of clay and organic matter. The experimental data were fitted using the Freundlich isotherm model and the Freundlich coefficients (K F obtained for each soil varied from 7 to 29 L kg-1, representing a low to medium sorption capacity, according to the IBAMA (Brazilian Environmental Protection Agency standards. The amounts of organic matter and clay were the most important soil parameters controling the sorption of methylparathion by these soils.

Set-up of polarographic analytical methods in the framework of nuclear reactor dismantling en of the decontamination of metallic pieces

International Nuclear Information System (INIS)

Poirier, S.; Rahier, A.

1996-06-01

Differential pulse polarography has been used to measure several chemical species, relevant to the dismantling and the decontamination of a nuclear power reactor. First, a method which allows the determination of low concentrations of Co in stainless steels has been studied. Co 3+ is reduced in the presence of ethylenediamine at pH 7.5 at -0.47 V vs Ag/AgCl sat. A preliminary extraction of iron (and partially chromium) in diethylether is required. Interferences with iron and nickel have been completely eliminated without using any precipitation technique. Some complications may result from the precipitation of residual Cr 3+ in the presence of EDA, even when fluorides are added. Next, the measurements of the main components of steels have been carried out successfully. The reduction of CrO 4 2- is observed at -0.46 V vs Ag/AgCl sat. in a medium containing 0.1 M KOH, 0.5 M citric acid and 1 M NH 3 . Adding dimethylglyoxime in the same medium allows to identify the reduction to Fe 2+ and Ni 2+ respectively at -1.65 and -1.13 V vs Ag/AgCl sat. Finally, the reduction to Cr 3+ is observed at -1.2 V vs Ag/AgCl sat. in an acetic buffer containing 0.1 M EDTA

Investigation of signal processing algorithms for an embedded microcontroller-based wearable pulse oximeter.

Science.gov (United States)

Johnston, W S; Mendelson, Y

2006-01-01

Despite steady progress in the miniaturization of pulse oximeters over the years, significant challenges remain since advanced signal processing must be implemented efficiently in real-time by a relatively small size wearable device. The goal of this study was to investigate several potential digital signal processing algorithms for computing arterial oxygen saturation (SpO(2)) and heart rate (HR) in a battery-operated wearable reflectance pulse oximeter that is being developed in our laboratory for use by medics and first responders in the field. We found that a differential measurement approach, combined with a low-pass filter (LPF), yielded the most suitable signal processing technique for estimating SpO(2), while a signal derivative approach produced the most accurate HR measurements.

Difference-frequency generation in the field of a few-cycle laser pulse propagating in a GaAs crystal with a domain structure

International Nuclear Information System (INIS)

Oganesyan, David L; Vardanyan, Aleksandr O; Oganesyan, G D

2013-01-01

Difference-frequency generation in a GaAs crystal with a periodic domain structure in the field of a few-cycle laser pulse is considered for the case of weakly pronounced material dispersion. The straight-line method is used to solve numerically the system of coupled nonlinear partial differential equations describing the evolution of the electric field of this laser pulse in GaAs crystals with periodic and chirped domain structures. It is shown that application of a GaAs crystal with a chirped domain structure makes it possible to control the frequency-modulation law for a broadband differencefrequency pulse. (nonlinear optical phenomena)

Development of bipolar-pulse accelerator for intense pulsed ion beam acceleration

Energy Technology Data Exchange (ETDEWEB)

Masugata, Katsumi [Department of Electrical and Electronic System Engineering, Toyama University, 3190 Gofuku, Toyama 930-8555 (Japan)]. E-mail: masugata@eng.toyama-u.ac.jp; Shimizu, Yuichro [Department of Electrical and Electronic System Engineering, Toyama University, 3190 Gofuku, Toyama 930-8555 (Japan); Fujioka, Yuhki [Department of Electrical and Electronic System Engineering, Toyama University, 3190 Gofuku, Toyama 930-8555 (Japan); Kitamura, Iwao [Department of Electrical and Electronic System Engineering, Toyama University, 3190 Gofuku, Toyama 930-8555 (Japan); Tanoue, Hisao [National Institute of Advanced Industry Science and Technology, 1-1-1, Umezono, Tsukuba-shi, Ibaraki 305-8568 (Japan); Arai, Kazuo [National Institute of Advanced Industry Science and Technology, 1-1-1, Umezono, Tsukuba-shi, Ibaraki 305-8568 (Japan)

2004-12-21

To improve the purity of intense pulsed ion beams, a new type of pulsed ion beam accelerator named 'bipolar pulse accelerator' was proposed. To confirm the principle of the accelerator a prototype of the experimental system was developed. The system utilizes By type magnetically insulated acceleration gap and operated with single polar negative pulse. A coaxial gas puff plasma gun was used as an ion source, which was placed inside the grounded anode. Source plasma (nitrogen) of current density {approx}25A/cm2, duration {approx}1.5{mu}s was injected into the acceleration gap by the plasma gun. The ions were successfully accelerated from the grounded anode to the drift tube by applying negative pulse of voltage 240kV, duration 100ns to the drift tube. Pulsed ion beam of current density {approx}40A/cm2, duration {approx}50ns was obtained at 41mm downstream from the anode surface. To evaluate the irradiation effect of the ion beam to solid material, an amorphous silicon thin film of thickness {approx}500nm was used as the target, which was deposited on the glass substrate. The film was found to be poly-crystallized after 4-shots of the pulsed nitrogen ion beam irradiation.

Characterization of Temperature Induced Phase Transitions in the Five Polymorphic Forms of Sulfathia-zole by Terahertz Pulsed Spectroscopy and Differential Scanning Calorimetry

DEFF Research Database (Denmark)

Zeitler, J. Axel; Newnham, David A.; Taday, Philip F.

2006-01-01

The far-infrared properties of all five described polymorphic forms of the drug sulfathiazole have been studied by terahertz pulsed spectroscopy and low frequency Raman spectroscopy. The spectra of the different polymorphs are distinctly different. Terahertz pulsed spectroscopy proves to be a rap...

Peculiarity of counterion - polyion interactions in aqueous solutions of copolymers of acrylamide with cadmium acrylate

Energy Technology Data Exchange (ETDEWEB)

Myagchenkov, V A; Kurenkov, V F; Akhmed' yanova, R A [Kazanskij Khimiko-Tekhnologicheskij Inst. (USSR)

1984-02-01

Binding of Cd/sup 2 +/ ions in aqueous solutions of statistical copolymers of acrylamide with cadmium acrylate with different content of ionogenic groups in copolymers was investigated by polarography, conductometry, viscometry and dialysis. It is shown that the degree of binding of Cd/sup 2 +/ ions increases with increasing of the content of ionogenic groups in the copolymer and with decreasing of ionic strength of the solution. The values of the degree of binding of Cd/sup 2 +/ ions obtained by polarography and dialysis show satisfactory agreement.

Erbium:ytterbium fiber-laser system delivering watt-level femtosecond pulses using divided pulse amplification

Science.gov (United States)

Herda, Robert; Zach, Armin

2015-03-01

We present an Erbium:Ytterbium codoped fiber-amplifer system based on Divided-Pulses-Amplification (DPA) for ultrashort pulses. The output from a saturable-absorber mode-locked polarization-maintaining (PM) fiber oscillator is amplified in a PM normal-dispersion Erbium-doped fiber. After this stage the pulses are positively chirped and have a duration of 2.0 ps at an average power of 93 mW. A stack of 5 birefringent Yttrium-Vanadate crystals divides these pulses 32 times. We amplify these pulses using a double-clad Erbium:Ytterbium codoped fiber pumped through a multimode fiber combiner. The pulses double pass the amplifier and recombine in the crystals using non-reciprocal polarization 90° rotation by a Faraday rotating mirror. Pulses with a duration of 144 fs are obtained after separation from the input beam using a polarizing beam splitter cube. These pulses have an average power of 1.85 W at a repetition rate of 80 MHz. The generation of femtosecond pulses directly from the amplifier was enabled by a positively chirped seed pulse, normally dispersive Yttrium-Vanadate crystals, and anomalously dispersive amplifier fibers. Efficient frequency doubling to 780 nm with an average power of 725 mW and a pulse duration of 156 fs is demonstrated. In summary we show a DPA setup that enables the generation of femtosecond pulses at watt-level at 1560 nm without the need for further external dechirping and demonstrate a good pulse quality by efficient frequency doubling. Due to the use of PM fiber components and a Faraday rotator the setup is environmentally stable.

DogPulse

DEFF Research Database (Denmark)

Skovgaard, Christoffer; Thomsen, Josephine Raun; Verdezoto, Nervo

2015-01-01

This paper presents DogPulse, an ambient awareness system to support the coordination of dog walking among family members at home. DogPulse augments a dog collar and leash set to activate an ambient shape-changing lamp and visualize the last time the dog was taken for a walk. The lamp gradually...... changes its form and pulsates its lights in order to keep the family members aware of the dog walking activity. We report the iterative prototyping of DogPulse, its implementation and its preliminary evaluation. Based on our initial findings, we present the limitations and lessons learned as well...

Optimization methods of pulse-to-pulse alignment using femtosecond pulse laser based on temporal coherence function for practical distance measurement

Science.gov (United States)

Liu, Yang; Yang, Linghui; Guo, Yin; Lin, Jiarui; Cui, Pengfei; Zhu, Jigui

2018-02-01

An interferometer technique based on temporal coherence function of femtosecond pulses is demonstrated for practical distance measurement. Here, the pulse-to-pulse alignment is analyzed for large delay distance measurement. Firstly, a temporal coherence function model between two femtosecond pulses is developed in the time domain for the dispersive unbalanced Michelson interferometer. Then, according to this model, the fringes analysis and the envelope extraction process are discussed. Meanwhile, optimization methods of pulse-to-pulse alignment for practical long distance measurement are presented. The order of the curve fitting and the selection of points for envelope extraction are analyzed. Furthermore, an averaging method based on the symmetry of the coherence function is demonstrated. Finally, the performance of the proposed methods is evaluated in the absolute distance measurement of 20 μ m with path length difference of 9 m. The improvement of standard deviation in experimental results shows that these approaches have the potential for practical distance measurement.

Pulse frequency in pulsed brachytherapy based on tissue repair kinetics

International Nuclear Information System (INIS)

Sminia, Peter; Schneider, Christoph J.; Koedooder, Kees; Tienhoven, Geertjan van; Blank, Leo E.C.M.; Gonzalez Gonzalez, Dionisio

1998-01-01

Purpose: Investigation of normal tissue sparing in pulsed brachytherapy (PB) relative to continuous low-dose rate irradiation (CLDR) by adjusting pulse frequency based on tissue repair characteristics. Method: Using the linear quadratic model, the relative effectiveness (RE) of a 20 Gy boost was calculated for tissue with an α/β ratio ranging from 2 to 10 Gy and a half-time of sublethal damage repair between 0.1 and 3 h. The boost dose was considered to be delivered either in a number of pulses varying from 2 to 25, or continuously at a dose rate of 0.50, 0.80, or 1.20 Gy/h. Results: The RE of 20 Gy was found to be identical for PB in 25 pulses of 0.80 Gy each h and CLDR delivered at 0.80 Gy/h for any α/β value and for a repair half-time > 0.75 h. When normal tissue repair half-times are assumed to be longer than tumor repair half-times, normal tissue sparing can be obtained, within the restriction of a fixed overall treatment time, with higher dose per pulse and longer period time (time elapsed between start of pulse n and start of pulse n + 1). An optimum relative normal tissue sparing larger than 10% was found with 4 pulses of 5 Gy every 8 h. Hence, a therapeutic gain might be obtained when changing from CLDR to PB by adjusting the physical dose in such a way that the biological dose on the tumor is maintained. The normal tissue-sparing phenomenon can be explained by an increase in RE with longer period time for tissue with high α/β ratio and fast or intermediate repair half-time, and the RE for tissue with low α/β ratio and long repair half-time remains almost constant. Conclusion: Within the benchmark of the LQ model, advantage in normal tissue-sparing is expected when matching the pulse frequency to the repair kinetics of the normal tissue exposed. A period time longer than 1 h may lead to a reduction of late normal tissue complications. This theoretical advantage emphasizes the need for better knowledge of human tissue-repair kinetics

Controlling output pulse and prepulse in a resonant microwave pulse compressor

International Nuclear Information System (INIS)

Shlapakovski, A.; Artemenko, S.; Chumerin, P.; Yushkov, Yu.

2013-01-01

A resonant microwave pulse compressor with a waveguide H-plane-tee-based energy extraction unit was studied in terms of its capability to produce output pulses that comprise a low-power long-duration (prepulse) and a high-power short-duration part. The application of such combined pulses with widely variable prepulse and high-power pulse power and energy ratios is of interest in the research area of electronic hardware vulnerability. The characteristics of output radiation pulses are controlled by the variation of the H-plane tee transition attenuation at the stage of microwave energy storage in the compressor cavity. Results of theoretical estimations of the parameters tuning range and experimental investigations of the prototype S-band compressor (1.5 MW, 12 ns output pulse; ∼13.2 dB gain) are presented. The achievable maximum in the prepulse power is found to be about half the power of the primary microwave source. It has been shown that the energy of the prepulse becomes comparable with that of the short-duration (nanosecond) pulse, while the power of the latter decreases insignificantly. The possible range of variation of the prepulse power and energy can be as wide as 40 dB. In the experiments, the prepulse level control within the range of ∼10 dB was demonstrated.

Dynamics of traveling reaction pulses

International Nuclear Information System (INIS)

Dovzhenko, A. Yu.; Rumanov, E. N.

2007-01-01

The growth of activator losses is accompanied by the decay of a traveling reaction pulse. In a ring reactor, this propagation threshold is present simultaneously with a threshold related to the ring diameter. The results of numerical experiments with pulses of an exothermal reaction reveal the transition from pulse propagation to a homogeneous hot regime, established regimes with periodic variations of the pulse velocity, and oscillatory decay of the pulse. When the medium becomes 'bistable' as a result of the variation in parameters, this factor does not prevent the propagation of pulses, but leads to changes in the pulse structure

River water remediation using pulsed corona, pulsed spark or ozonation

Energy Technology Data Exchange (ETDEWEB)

Izdebski, T.; Dors, M. [Polish Academy of Sciences, Szewalski Inst. of Fluid Flow Machiney, Fiszera (Poland). Centre for Plasma and Laser Engineering; Mizeraczyk, J. [Polish Academy of Sciences, Szewalski Inst. of Fluid Flow Machiney, Fiszera (Poland). Centre for Plasma and Laser Engineering; Gdynia Maritime Univ., Morska (Poland). Dept. of Marine Electronics

2010-07-01

The most common reason for epidemic formation is the pollution of surface and drinking water by wastewater bacteria. Pathogenic microorganisms that form the largest part of this are fecal bacteria, such as escherichia coli (E. coli). Wastewater treatment plants reduce the amount of the fecal bacteria by 1-3 orders of magnitude, depending on the initial number of bacteria. There is a lack of data on waste and drinking water purification by the electrohydraulic discharges method, which causes the destruction and inactivation of viruses, yeast, and bacteria. This paper investigated river water cleaning from microorganisms using pulsed corona, spark discharge and ozonization. The paper discussed the experimental setup and results. It was concluded that ozonization is the most efficient method of water disinfection as compared with pulsed spark and pulsed corona discharges. The pulsed spark discharge in water was capable of killing all microorganism similarly to ozonization, but with much lower energy efficiency. The pulsed corona discharge was found to be the less effective method of water disinfection. 21 refs., 4 figs.

Physical model of reactor pulse

International Nuclear Information System (INIS)

Petrovic, A.; Ravnik, M.

2004-01-01

Pulse experiments have been performed at J. Stefan Institute TRIGA reactor since 1991. In total, more than 130 pulses have been performed. Extensive experimental information on the pulse physical characteristics has been accumulated. Fuchs-Hansen adiabatic model has been used for predicting and analysing the pulse parameters. The model is based on point kinetics equation, neglecting the delayed neutrons and assuming constant inserted reactivity in form of step function. Deficiencies of the Fuchs-Hansen model and systematic experimental errors have been observed and analysed. Recently, the pulse model was improved by including the delayed neutrons and time dependence of inserted reactivity. The results explain the observed non-linearity of the pulse energy for high pulses due to finite time of pulse rod withdrawal and the contribution of the delayed neutrons after the prompt part of the pulse. The results of the improved model are in good agreement with experimental results. (author)

Dual-Pulse Pulse Position Modulation (DPPM) for Deep-Space Optical Communications: Performance and Practicality Analysis

Science.gov (United States)

Li, Jing; Hylton, Alan; Budinger, James; Nappier, Jennifer; Downey, Joseph; Raible, Daniel

2012-01-01

Due to its simplicity and robustness against wavefront distortion, pulse position modulation (PPM) with photon counting detector has been seriously considered for long-haul optical wireless systems. This paper evaluates the dual-pulse case and compares it with the conventional single-pulse case. Analytical expressions for symbol error rate and bit error rate are first derived and numerically evaluated, for the strong, negative-exponential turbulent atmosphere; and bandwidth efficiency and throughput are subsequently assessed. It is shown that, under a set of practical constraints including pulse width and pulse repetition frequency (PRF), dual-pulse PPM enables a better channel utilization and hence a higher throughput than it single-pulse counterpart. This result is new and different from the previous idealistic studies that showed multi-pulse PPM provided no essential information-theoretic gains than single-pulse PPM.

Fast neutron detection using a new pulse shape discrimination technique: Charge sensitive integration

International Nuclear Information System (INIS)

Zucker, M.; Tsoupas, N.; Karwowski, H.; Castaneda, C.; Nimnual, S.; Porter, R.; Ward, T.

1988-01-01

A new electronic technique that depends on charge sensitive integration (CSI) has been developed and tested using a CAMAC based pulse shape discrimination system. Neutrons are well separated from γ-ray signals in the 0.1-100 MeV energy range. The new method was compared with the old zero-crossing time-to-amplitude differentiating technique and was found to be comparable in count rate and superior in noise suppression

Controlled generation of a single Trichel pulse and a series of single Trichel pulses in air

Science.gov (United States)

Mizeraczyk, Jerzy; Berendt, Artur; Akishev, Yuri

2018-04-01

In this paper, a simple method for the controlled generation of a single Trichel pulse or a series of single Trichel pulses of a regulated repetition frequency in air is proposed. The concept of triggering a single Trichel pulse or a series of such pulses is based on the precise controlling the voltage inception of the negative corona, which can be accomplished through the use of a ramp voltage pulse or a series of such pulses with properly chosen ramp voltage pulse parameters (rise and fall times, and ramp voltage pulse repetition frequency). The proposal has been tested in experiments using a needle-to-plate electrode arrangement in air, and reproducible Trichel pulses (single or in a series) were obtained by triggering them with an appropriately designed voltage waveform. The proposed method and results obtained have been qualitatively analysed. The analysis provides guidance for designing the voltage ramp pulse in respect of the generation of a single Trichel pulse or a series of single Trichel pulses. The controlled generation of a single Trichel pulse or a series of such pulses would be a helpful research tool for the refined studies of the fundamental processes in a negative corona discharge in a single- (air is an example) and multi-phase gaseous fluids. The controlled generation of a single Trichel pulse or a series of Trichel pulses can also be attractive for those corona treatments which need manipulation of the electric charge and heat portions delivered by the Trichel pulses to the object.

A high pulsed power supply system designed for pulsed high magnetic field

International Nuclear Information System (INIS)

Liu Kefu; Wang Shaorong; Zhong Heqing; Xu Yan; Pan Yuan

2008-01-01

This paper introduces the design of high pulsed power supply system for producing pulsed high magnetic field up to 70 T. This system consists of 58 sets of 55 μF of capacitor bank which provides 1.0 MJ energy storage. A set of vacuum closing switch is chosen as main switch for energy discharge into magnetic coil. A crowbar circuit with high power diodes in series with resistor is used to absorb the redundant energy and adjust pulse width. The resistance of magnetic coil changing with current is deduced by energy balance equations. A capacitor-charging power supply using a series-resonant, constant on-time variable frequency control, and zero-current switching charges the capacitor bank in one minute time with high efficiency. The pulsed power supply provides adjustable current and pulse width with 30 kA peak and 30 ms maximum. The primary experiments demonstrate the system reliability. This work provides an engineering guidance for future development of pulsed high magnetic field. (authors)

A Simple, Cost-Effective Sensor for Detecting Lead Ions in Water Using Under-Potential Deposited Bismuth Sub-Layer with Differential Pulse Voltammetry (DPV)

Science.gov (United States)

Dai, Yifan; Liu, Chung Chiun

2017-01-01

This research has developed a simple to use, cost effective sensor system for the detection of lead ions in tap water. An under-potential deposited bismuth sub-layer on a thin gold film based electrochemical sensor was designed, manufactured, and evaluated. Differential pulse voltammetry (DPV) measurement technique was employed in this detection. Tap water from the Cleveland, OH, USA regional water district was the test medium. Concentrations of lead ion in the range of 8 × 10−7 M to 5 × 10−4 M were evaluated, showing a good sensitivity over this concentration range. The calibration curve for the DPV measurements of lead ions in tap water showed excellent reproducibility with R2 value of 0.970. This DPV detection system required 3–6 min to complete the detection measurement. A longer measurement time of 6 min was used for the lower lead ion concentration. The selectivity of this lead ion sensor was very good, and Fe III, Cu II, Ni II, and Mg II at a concentration level of 5 × 10−4 M did not interfere with the lead ion measurement. PMID:28441356

Factors affecting the simultaneous determination of copper, lead, cadmium, and zinc concentrations in human head hair using differential pulse anodic stripping voltammetry method

International Nuclear Information System (INIS)

Wandiga, S.O.; Jumba, I.O.

1982-01-01

Conditions of analysis of copper, lead, cadmium and zinc content in human hair using differential pulse anodic stripping voltammetry (DPASV) and hanging mercury drop electrode (HMDE) have been established. Sample digestion using using the mixture HCI; H 2 O 2 ;HNO 3 in the ratio 2:1:40 by volume gave the best wet-ashing procedure. The peak currents and peak potentials of zinc, cadmium and lead, copper were maximum at pH 6-7 and 1-3 respectively, when excess H 2 O 2 was eliminated with subsequent addition of hydroxyamine hydrochloride. Matrix concentration effects were minimized by digesting weights not exceeding 50 mg per sample. The effect of selenium (IV) was negligible and was ignored. The detection limit of 0.0036 ng/cm 3 for Cd + 2 was obtained while the values for zinc, lead and copper were 0.0230, 0.0287 and 0.0269 ng/cm 3 respectively at the 95% confidence limit. The observed DPASV condition of analysis of these metals are useful for routine determination of the metals in human hair and should complement the conventional flame absorption spectrophotometry method. (author)

CW seeded optical parametric amplifier providing wavelength and pulse duration tunable nearly transform limited pulses.

Science.gov (United States)

Hädrich, S; Gottschall, T; Rothhardt, J; Limpert, J; Tünnermann, A

2010-02-01

An optical parametric amplifier that delivers nearly transform limited pulses is presented. The center wavelength of these pulses can be tuned between 993 nm and 1070 nm and, at the same time, the pulse duration is varied between 206 fs and 650 fs. At the shortest pulse duration the pulse energy was increased up to 7.2 microJ at 50 kHz repetition rate. Variation of the wavelength is achieved by applying a tunable cw seed while the pulse duration can be varied via altering the pump pulse duration. This scheme offers superior flexibility and scaling possibilities.

Nonlinear Pulse Shaping in Fibres for Pulse Generation and Optical Processing

Directory of Open Access Journals (Sweden)

Sonia Boscolo

2012-01-01

Full Text Available The development of new all-optical technologies for data processing and signal manipulation is a field of growing importance with a strong potential for numerous applications in diverse areas of modern science. Nonlinear phenomena occurring in optical fibres have many attractive features and great, but not yet fully explored, potential in signal processing. Here, we review recent progress on the use of fibre nonlinearities for the generation and shaping of optical pulses and on the applications of advanced pulse shapes in all-optical signal processing. Amongst other topics, we will discuss ultrahigh repetition rate pulse sources, the generation of parabolic shaped pulses in active and passive fibres, the generation of pulses with triangular temporal profiles, and coherent supercontinuum sources. The signal processing applications will span optical regeneration, linear distortion compensation, optical decision at the receiver in optical communication systems, spectral and temporal signal doubling, and frequency conversion.

Pulsed neutron generator for use with pulsed neutron activation techniques

International Nuclear Information System (INIS)

Rochau, G.E.

1980-01-01

A high-output, transportable, pulsed neutron generator has been developed by Sandia National Laboratories for use with Pulsed Neutron Activation (PNA) techniques. The PNA neutron generator generates > 10 10 14 MeV D-T neutrons in a 1.2 millisecond pulse. Each operation of the unit will produce a nominal total neutron output of 1.2 x 10 10 neutrons. The generator has been designed to be easily repaired and modified. The unit requires no additional equipment for operation or measurement of output

Effect of laser pulse energies in laser induced breakdown spectroscopy in double-pulse configuration

International Nuclear Information System (INIS)

Benedetti, P.A.; Cristoforetti, G.; Legnaioli, S.; Palleschi, V.; Pardini, L.; Salvetti, A.; Tognoni, E.

2005-01-01

In this paper, the effect of laser pulse energy on double-pulse laser induced breakdown spectroscopy signal is studied. In particular, the energy of the first pulse has been changed, while the second pulse energy is held fixed. A systematic study of the laser induced breakdown spectroscopy signal dependence on the interpulse delay is performed, and the results are compared with the ones obtained with a single laser pulse of energy corresponding to the sum of the two pulses. At the same time, the crater formed at the target surface is studied by video-confocal microscopy, and the variation in crater dimensions is correlated to the enhancement of the laser induced breakdown spectroscopy signal. The results obtained are consistent with the interpretation of the double-pulse laser induced breakdown spectroscopy signal enhancement in terms of the changes in ambient gas pressure produced by the shock wave induced by the first laser pulse

Dose reduction in pulsed fluoroscopy by modifying the high-voltage pulse shape

International Nuclear Information System (INIS)

Sabau, M.N.; Phelps, G.

1988-01-01

This paper presents the dose reduction results in pulsed fluoroscopy by modifying the high-voltage pulse shape (HVPS). Since the HVPS in regular pulsed fluoroscopy has a long tail, the radiation pulse shape (RPS) is similar. Using specially designed circuitry in the high-voltage generator to produce a rectangular HVPS, and consequently a rectangular RPS, it was possible to obtain a reduction of up to 25% of patient exposure. This dose reduction obtained by cutting the long tail of RPS does not damage the image quality

Apparatus for generating nonlinear pulse patterns

Science.gov (United States)

Nakamura, N.M.I.

Apparatus for generating a plurality of nonlinear pulse patterns from a single linear pulse pattern. A first counter counts the pulses of the linear pulse pattern and a second counter counts the pulses of the nonlinear pulse pattern. A comparator compares the counts of both counters, and in response to an equal count, a gate is enabled to gate a pulse of the linear pattern as a pulse of the nonlinear pattern, the latter also resetting the first counter. Presettable dividers divide the pulses of each pattern before they are counted by the respective counters. Apparatus for generating a logarithmic pulse pattern from a linear pulse pattern to any log base is described. In one embodiment, a shift register is used in place of the second counter to be clocked by each pulse of the logarithmic pattern to generate the pattern. In another embodiment, a memory stores the logarithmic pattern and is addressed by the second counter which is clocked by the pulses of the logarithmic pulse pattern.

Pulsed neutron generator for mass flow measurement using the pulsed neutron activation technique

International Nuclear Information System (INIS)

Rochau, G.E.; Hornsby, D.R.; Mareda, J.F.; Riggan, W.C.

1980-01-01

A high-output, transportable neutron generator has been developed to measure mass flow velocities in reactor safety tests using the Pulsed Neutron Activation (PNA) Technique. The PNA generator produces >10 10 14 MeV D-T neutrons in a 1.2 millisecond pulse. The Millisecond Pulse (MSP) Neutron Tube, developed for this application, has an expected operational life of 1000 pulses, and it limits the generator pulse repetition rate to 12 pulses/minute. A semiconductor neutron detector is included in the generator package to monitor the neutron output. The control unit, which can be operated manually or remotely, also contains a digital display with a BCD output for the neutron monitor information. The digital logic of the unit controls the safety interlocks and rejects transient signals which could accidently fire the generator

High current transistor pulse generator

International Nuclear Information System (INIS)

Nesterov, V.; Cassel, R.

1991-05-01

A solid state pulse generator capable of delivering high current trapezoidally shaped pulses into an inductive load has been developed at SLAC. Energy stored in the capacitor bank of the pulse generator is switched to the load through a pair of Darlington transistors. A combination of diodes and Darlington transistors is used to obtain trapezoidal or triangular shaped current pulses into an inductive load and to recover the remaining energy in the same capacitor bank without reversing capacitor voltage. The transistors work in the switch mode, and the power losses are low. The rack mounted pulse generators presently used at SLAC contain a 660 microfarad storage capacitor bank and can deliver 400 amps at 800 volts into inductive loads up to 3 mH. The pulse generators are used in several different power systems, including pulse to pulse bipolar power supplies and in application with current pulses distributed into different inductive loads. The current amplitude and discharge time are controlled by the central computer system through a specially developed multichannel controller. Several years of operation with the pulse generators have proven their consistent performance and reliability. 8 figs

Differential pulse voltammetric determination of methyl parathion based on multiwalled carbon nanotubes–poly(acrylamide) nanocomposite film modified electrode

International Nuclear Information System (INIS)

Zeng, Yanbo; Yu, Dajun; Yu, Yanyan; Zhou, Tianshu; Shi, Guoyue

2012-01-01

Highlights: ► A sensitive electrochemical sensor for detecting methyl parathion in environmental samples. ► The preparation, characterization and application of this novel MWCNTs–PAAM nanocomposite. ► The MWCNTs–PAAM/GCE exhibited a high adsorption and strong affinity toward methyl parathion. ► Wide linear range and low detection limit of the proposed method for detecting methyl parathion. - Abstract: A sensitive electrochemical differential pulse voltammetry method was developed for detecting methyl parathion based on multiwalled carbon nanotubes–poly(acrylamide) (MWCNTs–PAAM) nanocomposite film modified glassy carbon electrode. The novel MWCNTs–PAAM nanocomposite, containing high content of amide groups, was synthesized by PAAM polymerizing at the vinyl group functionalized MWCNTs surface using free radical polymerization. The MWCNTs–PAAM nanocomposite was characterized by Fourier transform infrared spectroscopy, thermal gravimetric analysis and scanning electron microscopy. Electrochemical behavior and interference studies of MWCNTs–PAAM/GCE for methyl parathion were investigated. The experimental results demonstrated that the MWCNTs–PAAM/GCE exhibited a high adsorption and strong affinity toward methyl parathion compared with some metal ions and nitroaromatic compounds, which exist in environmental samples. The adsorbed amount of methyl parathion on the MWCNTs–PAAM/GCE approached the equilibrium value upon 5 min adsorption time. A linear calibration curve for methyl parathion was obtained in the concentration range from 5.0 × 10 −9 to 1.0 × 10 −5 mol L −1 , with a detection limit of 2.0 × 10 −9 mol L −1 . The MWCNTs–PAAM/GCE was proved to be a suitable sensing tool for the fast, sensitive and selective determination of methyl parathion in environmental water samples.

Experimental photonic generation of chirped pulses using nonlinear dispersion-based incoherent processing.

Science.gov (United States)

Rius, Manuel; Bolea, Mario; Mora, José; Ortega, Beatriz; Capmany, José

2015-05-18

We experimentally demonstrate, for the first time, a chirped microwave pulses generator based on the processing of an incoherent optical signal by means of a nonlinear dispersive element. Different capabilities have been demonstrated such as the control of the time-bandwidth product and the frequency tuning increasing the flexibility of the generated waveform compared to coherent techniques. Moreover, the use of differential detection improves considerably the limitation over the signal-to-noise ratio related to incoherent processing.

Pulse power modulators - an overview

International Nuclear Information System (INIS)

Venkatramani, N.

2006-01-01

Pulse power modulators are electronic devices to provide, high voltage, high current, power bursts. Ideally, a modulator, with the means to shape and control the pulses, acts as a switch between a high voltage power supply and its load. This article gives an overview of the pulse power modulators: starting with the basics of pulse and modulation, it covers modulation topologies, different types of modulators, major subsystems and pulse measurement techniques. The various applications of pulse power modulators and the recent trends have been included at the end. (author)

Pulse frequency dependency of photobiomodulation on the bioenergetic functions of human dental pulp stem cells.

Science.gov (United States)

Kim, Hong Bae; Baik, Ku Youn; Choung, Pill-Hoon; Chung, Jong Hoon

2017-11-21

Photobiomodulation (PBM) therapy contributes to pain relief, wound healing, and tissue regeneration. The pulsed wave (PW) mode has been reported to be more effective than the continuous wave (CW) mode when applying PBM to many biological systems. However, the reason for the higher effectiveness of PW-PBM is poorly understood. Herein, we suggest using delayed luminescence (DL) as a reporter of mitochondrial activity after PBM treatment. DL originates mainly from mitochondrial electron transport chain systems, which produce reactive oxygen species (ROS) and adenosine triphosphate (ATP). The decay time of DL depends on the pulse frequencies of applied light, which correlate with the biological responses of human dental pulp stem cells (hDPSCs). Using a low-power light whose wavelength is 810 nm and energy density is 38 mJ/cm 2 , we find that a 300-Hz pulse frequency prolonged the DL pattern and enhanced alkaline phosphatase activity. In addition, we analyze mitochondrial morphological changes and their volume density and find evidence supporting mitochondrial physiological changes from PBM treatment. Our data suggest a new methodology for determining the effectiveness of PBM and the specific pulse frequency dependency of PBM in the differentiation of hDPSCs.

Simulations of NMR pulse sequences during equilibrium and non-equilibrium chemical exchange

International Nuclear Information System (INIS)

Helgstrand, Magnus; Haerd, Torleif; Allard, Peter

2000-01-01

The McConnell equations combine the differential equations for a simple two-state chemical exchange process with the Bloch differential equations for a classical description of the behavior of nuclear spins in a magnetic field. This equation system provides a useful starting point for the analysis of slow, intermediate and fast chemical exchange studied using a variety of NMR experiments. The McConnell equations are in the mathematical form of an inhomogeneous system of first-order differential equations. Here we rewrite the McConnell equations in a homogeneous form in order to facilitate fast and simple numerical calculation of the solution to the equation system. The McConnell equations can only treat equilibrium chemical exchange. We therefore also present a homogeneous equation system that can handle both equilibrium and non-equilibrium chemical processes correctly, as long as the kinetics is of first-order. Finally, the same method of rewriting the inhomogeneous form of the McConnell equations into a homogeneous form is applied to a quantum mechanical treatment of a spin system in chemical exchange. In order to illustrate the homogeneous McConnell equations, we have simulated pulse sequences useful for measuring exchange rates in slow, intermediate and fast chemical exchange processes. A stopped-flow NMR experiment was simulated using the equations for non-equilibrium chemical exchange. The quantum mechanical treatment was tested by the simulation of a sensitivity enhanced 15 N-HSQC with pulsed field gradients during slow chemical exchange and by the simulation of the transfer efficiency of a two-dimensional heteronuclear cross-polarization based experiment as a function of both chemical shift difference and exchange rate constants

Ultrashort laser pulses and electromagnetic pulse generation in air and on dielectric surfaces

International Nuclear Information System (INIS)

Sprangle, P.; Penano, J.R.; Hafizi, B.; Kapetanakos, C.A.

2004-01-01

Intense, ultrashort laser pulses propagating in the atmosphere have been observed to emit sub-THz electromagnetic pulses (EMPS). The purpose of this paper is to analyze EMP generation from the interaction of ultrashort laser pulses with air and with dielectric surfaces and to determine the efficiency of conversion of laser energy to EMP energy. In our self-consistent model the laser pulse partially ionizes the medium, forms a plasma filament, and through the ponderomotive forces associated with the laser pulse, drives plasma currents which are the source of the EMP. The propagating laser pulse evolves under the influence of diffraction, Kerr focusing, plasma defocusing, and energy depletion due to electron collisions and ionization. Collective effects and recombination processes are also included in the model. The duration of the EMP in air, at a fixed point, is found to be a few hundred femtoseconds, i.e., on the order of the laser pulse duration plus the electron collision time. For steady state laser pulse propagation the flux of EMP energy is nonradiative and axially directed. Radiative EMP energy is present only for nonsteady state or transient laser pulse propagation. The analysis also considers the generation of EMP on the surface of a dielectric on which an ultrashort laser pulse is incident. For typical laser parameters, the power and energy conversion efficiency from laser radiation to EMP radiation in both air and from dielectric surfaces is found to be extremely small, -8 . Results of full-scale, self-consistent, numerical simulations of atmospheric and dielectric surface EMP generation are presented. A recent experiment on atmospheric EMP generation is also simulated

A method to reduce the suppression of relevant pulses in pulse weight discriminators

International Nuclear Information System (INIS)

Schwartz, P.

1975-01-01

The pulse height analyzer is used, for instance, with proportional counters. Pulses are broken down into amplitude ranges in accordance with their maximum amplitudes. In pulse height analyzers with real time analog-digital conversion only one deadtime is needed for the respective range selected. For this purpose, all discriminator thresholds of the amplitude stores connected parallel are actuated as an input pulse arrives. The leading edges of the discriminator signals set the amplitude range flip-flop. Only the flip-flop circuit of the maximum amplitude range reached remains set whilst all the others are erased. The trailing edge of the discriminator signals actuates the evaluation of the information stored by the flip-flop circuit selected. It triggers a pulse extender and resets the flip-flop selected. Therefore, only the amplitude range selected needs a deadtime. The pulse extender in addition reduces the processing time of the analyzer by the output pulse length. The characteristic used for the trailing edge is the backward count of the real time analog-digital converter. (DG/RF) [de

Pulsed corona generation using a diode-based pulsed power generator

Science.gov (United States)

Pemen, A. J. M.; Grekhov, I. V.; van Heesch, E. J. M.; Yan, K.; Nair, S. A.; Korotkov, S. V.

2003-10-01

Pulsed plasma techniques serve a wide range of unconventional processes, such as gas and water processing, hydrogen production, and nanotechnology. Extending research on promising applications, such as pulsed corona processing, depends to a great extent on the availability of reliable, efficient and repetitive high-voltage pulsed power technology. Heavy-duty opening switches are the most critical components in high-voltage pulsed power systems with inductive energy storage. At the Ioffe Institute, an unconventional switching mechanism has been found, based on the fast recovery process in a diode. This article discusses the application of such a "drift-step-recovery-diode" for pulsed corona plasma generation. The principle of the diode-based nanosecond high-voltage generator will be discussed. The generator will be coupled to a corona reactor via a transmission-line transformer. The advantages of this concept, such as easy voltage transformation, load matching, switch protection and easy coupling with a dc bias voltage, will be discussed. The developed circuit is tested at both a resistive load and various corona reactors. Methods to optimize the energy transfer to a corona reactor have been evaluated. The impedance matching between the pulse generator and corona reactor can be significantly improved by using a dc bias voltage. At good matching, the corona energy increases and less energy reflects back to the generator. Matching can also be slightly improved by increasing the temperature in the corona reactor. More effective is to reduce the reactor pressure.

Laser ablation comparison by picosecond pulses train and nanosecond pulse

Science.gov (United States)

Lednev, V. N.; Filippov, M. N.; Bunkin, A. F.; Pershin, S. M.

2015-12-01

A comparison of laser ablation by a train of picosecond pulses and nanosecond pulses revealed a difference in laser craters, ablation thresholds, plasma sizes and spectral line intensities. Laser ablation with a train of picosecond pulses resulted in improved crater quality while ablated mass decreased up to 30%. A reduction in laser plasma dimensions for picosecond train ablation was observed while the intensity of atomic/ionic lines in the plasma spectra was greater by a factor of 2-4 indicating an improved excitation and atomization in the plasma.

Particle acceleration by electromagnetic pulses

International Nuclear Information System (INIS)

Lai, H.M.

1982-01-01

Particle interaction with plane electromagnetic pulses is studied. It is shown that particle acceleration by a wavy pulse, depending on the shape of the pulse, may not be small. Further, a diffusive-type particle acceleration by multiple weak pulses is described and discussed. (author)

Hybrid Pulsed Nd:YAG Laser

Science.gov (United States)

Miller, Sawyer; Trujillo, Skyler; Fort Lewis College Laser Group Team

This work concerns the novel design of an inexpensive pulsed Nd:YAG laser, consisting of a hybrid Kerr Mode Lock (KLM) and Q-switch pulse. The two pulse generation systems work independently, non simultaneously of each other, thus generating the ability for the user to easily switch between ultra-short pulse widths or large energy density pulses. Traditionally, SF57 glass has been used as the Kerr medium. In this work, novel Kerr mode-locking mediums are being investigated including: tellurite compound glass (TeO2), carbon disulfide (CS2), and chalcogenide glass. These materials have a nonlinear index of refraction orders of magnitude,(n2), larger than SF57 glass. The Q-switched pulse will utilize a Pockels cell. As the two pulse generation systems cannot be operated simultaneously, the Pockels cell and Kerr medium are attached to kinematic mounts, allowing for quick interchange between systems. Pulse widths and repetition rates will vary between the two systems. A goal of 100 picosecond pulse widths are desired for the mode-locked system. A goal of 10 nanosecond pulse widths are desired for the Q-switch system, with a desired repetition rate of 50 Hz. As designed, the laser will be useful in imaging applications.

Active heat pulse sensing of 3-D-flow fields in streambeds

Science.gov (United States)

Banks, Eddie W.; Shanafield, Margaret A.; Noorduijn, Saskia; McCallum, James; Lewandowski, Jörg; Batelaan, Okke

2018-03-01

Profiles of temperature time series are commonly used to determine hyporheic flow patterns and hydraulic dynamics in the streambed sediments. Although hyporheic flows are 3-D, past research has focused on determining the magnitude of the vertical flow component and how this varies spatially. This study used a portable 56-sensor, 3-D temperature array with three heat pulse sources to measure the flow direction and magnitude up to 200 mm below the water-sediment interface. Short, 1 min heat pulses were injected at one of the three heat sources and the temperature response was monitored over a period of 30 min. Breakthrough curves from each of the sensors were analysed using a heat transport equation. Parameter estimation and uncertainty analysis was undertaken using the differential evolution adaptive metropolis (DREAM) algorithm, an adaption of the Markov chain Monte Carlo method, to estimate the flux and its orientation. Measurements were conducted in the field and in a sand tank under an extensive range of controlled hydraulic conditions to validate the method. The use of short-duration heat pulses provided a rapid, accurate assessment technique for determining dynamic and multi-directional flow patterns in the hyporheic zone and is a basis for improved understanding of biogeochemical processes at the water-streambed interface.

Modeling study on the effects of pulse rise rate in atmospheric pulsed discharges

Science.gov (United States)

Zhang, Yuan-Tao; Wang, Yan-Hui

2018-02-01

In this paper, we present a modeling study on the discharge characteristics driven by short pulsed voltages, focusing on the effects of pulse rise rate based on the fluid description of atmospheric plasmas. The numerical results show that the breakdown voltage of short pulsed discharge is almost linearly dependent on the pulse rise rate, which is also confirmed by the derived equations from the fluid model. In other words, if the pulse rise rate is fixed as a constant, the simulation results clearly suggest that the breakdown voltage is almost unchanged, although the amplitude of pulsed voltage increases significantly. The spatial distribution of the electric field and electron density are given to reveal the underpinning physics. Additionally, the computational data and the analytical expression also indicate that an increased repetition frequency can effectively decrease the breakdown voltage and current density, which is consistent with the experimental observation.

Electrical addressing and temporal tweezing of localized pulses in passively mode-locked semiconductor lasers

Science.gov (United States)

Javaloyes, J.; Camelin, P.; Marconi, M.; Giudici, M.

2017-08-01

This work presents an overview of a combined experimental and theoretical analysis on the manipulation of temporal localized structures (LSs) found in passively Vertical-Cavity Surface-Emitting Lasers coupled to resonant saturable absorber mirrors. We show that the pumping current is a convenient parameter for manipulating the temporal Localized Structures, also called localized pulses. While short electrical pulses can be used for writing and erasing individual LSs, we demonstrate that a current modulation introduces a temporally evolving parameter landscape allowing to control the position and the dynamics of LSs. We show that the localized pulses drifting speed in this landscape depends almost exclusively on the local parameter value instead of depending on the landscape gradient, as shown in quasi-instantaneous media. This experimental observation is theoretically explained by the causal response time of the semiconductor carriers that occurs on an finite timescale and breaks the parity invariance along the cavity, thus leading to a new paradigm for temporal tweezing of localized pulses. Different modulation waveforms are applied for describing exhaustively this paradigm. Starting from a generic model of passive mode-locking based upon delay differential equations, we deduce the effective equations of motion for these LSs in a time-dependent current landscape.

Intense isolated attosecond pulse generation from relativistic laser plasmas using few-cycle laser pulses

International Nuclear Information System (INIS)

Ma, Guangjin; Dallari, William; Borot, Antonin; Tsakiris, George D.; Veisz, Laszlo; Krausz, Ferenc; Yu, Wei

2015-01-01

We have performed a systematic study through particle-in-cell simulations to investigate the generation of attosecond pulse from relativistic laser plasmas when laser pulse duration approaches the few-cycle regime. A significant enhancement of attosecond pulse energy has been found to depend on laser pulse duration, carrier envelope phase, and plasma scale length. Based on the results obtained in this work, the potential of attaining isolated attosecond pulses with ∼100 μJ energy for photons >16 eV using state-of-the-art laser technology appears to be within reach

Pulsed corona generation using a diode-based pulsed power generator

NARCIS (Netherlands)

Pemen, A.J.M.; Grekhov, I.V.; Heesch, van E.J.M.; Yan, K.; Nair, S.A.; Korotkov, S.V.

2003-01-01

Pulsed plasma techniques serve a wide range of unconventional processes, such as gas and water processing, hydrogen production, and nanotechnology. Extending research on promising applications, such as pulsed corona processing, depends to a great extent on the availability of reliable, efficient and

Ultrashort Laser Pulse Phenomena

CERN Document Server

Diels, Jean-Claude

2006-01-01

Ultrashort Laser Pulse Phenomena, 2e serves as an introduction to the phenomena of ultra short laser pulses and describes how this technology can be used to examine problems in areas such as electromagnetism, optics, and quantum mechanics. Ultrashort Laser Pulse Phenomena combines theoretical backgrounds and experimental techniques and will serve as a manual on designing and constructing femtosecond (""faster than electronics"") systems or experiments from scratch. Beyond the simple optical system, the various sources of ultrashort pulses are presented, again with emphasis on the basic

Multimode pulse counter

International Nuclear Information System (INIS)

Natanzon, D.D.

1982-01-01

A pulse counter with code conversion is described. The counter is based on the integrated circuits of direct-counting devices of medium integration. The counter ensures various modes of pulse counting depending on the logical control signals: reversible, two-channel summing, one-channel summing binary, summing with ''storage'' signal code fixation without interrupting pulse counting. Arrangement of the suggested structure as a microcircuit of medium integration might contribute to reduction in the counter type nomenclature in digital families of widely used integrated circuits

Powerful nanosecond pulse train generator

International Nuclear Information System (INIS)

Isakov, I.F.; Logachev, E.I.; Opekunov, M.S.; Pechenkin, S.A.; Remnev, G.E.; Usov, Yu.P.

1987-01-01

A generator permitting to shape on the load pulsed with the repetition frequency of 10 3 -10 6 Hz and more is described. The amplitude of shaped voltage pulses is up to 150 kV at pulse duration equal to 50 ns. The generator comprises connected in-series with the load two shaping and two transmission lines realized on the base of the KVI-300 low-ohmic cable. The shaping lines are supplied from two independently connected pulse voltage generators for obtaining time interval between pulses > 10 -6 s; they may be also supplied from one generator for obtaining time interval -6 s. At the expense of reducing losses in the discharge circuit the amplitude of the second pulse grows with increase of time interval between pulses up to 300 ns, further on the curve flat-topping exists. The described generator is used in high-current accelerators, in which the primary negative pulse results in generation of explosive-emission plasma, and the second positive pulse provides ion beam shaping including ions of heavy metal used for production of a potential electrode. The generator multipulse mode is used for successive ion acceleration in the transport system

High-voltage integrated transmitting circuit with differential driving for CMUTs

DEFF Research Database (Denmark)

Llimos Muntal, Pere; Larsen, Dennis Øland; Færch, Kjartan Ullitz

2016-01-01

In this paper, a high-voltage integrated differential transmitting circuit for capacitive micromachined ultrasonic transducers (CMUTs) used in portable ultrasound scanners is presented. Due to its application, area and power consumption are critical and need to be minimized. The circuitry...... is designed and implemented in AMS 0.35 μ m high-voltage process. Measurements are performed on the fabricated integrated circuit in order to assess its performance. The transmitting circuit consists of a low-voltage control logic, pulse-triggered level shifters and a differential output stage that generates...... conditions is 0.936 mW including the load. The integrated circuits measured prove to be consistent and robust to local process variations by measurements....

RIIM two-pulse injector experiments

International Nuclear Information System (INIS)

Mazarakis, M.G.; Smith, D.L.; Jones, E.E.; Hasti, D.E.; Jojola, J.M.; Lehmann, M.

1987-01-01

The RADLAC-II foilless diode injector was operated under double pulse conditions utilizing the RIIM accelerator as the test bed. The original RIIM accelerator pulse-power network was modified to provide for the generation, transmission, and delivery to the foilless diode of two distinct voltage pulses with variable interpulse separation from 0 to 2 ms. Two pulse-power assemblies were investigated and will be presented in connection with the diode performance. In both cases, the generated plasma and an excessive neutral gas release, following the first pulse, prevented the diode from producing a second beam pulse for interpulse separations larger than ∼1 μs. 4 refs

Femtosecond laser assisted photo-transfection and differentiation of mouse embryonic stem cells

Science.gov (United States)

Thobakgale, Lebogang; Manoto, Sello; Ombinda Lemboumba, Satuurnin; Maaza, Malik; Mthunzi-Kufa, Patience

2018-02-01

In tissue engineering research, stem cells have been used as starting material in the synthesis of mammalian cells for the treatment of various cell based diseases. This is done by manipulating the DNA content of the cells to induce a specific effect such as increased proliferation or developing a new cell type through the process of differentiation. Such controlled gene expression of stem cells is achieved by the method of transfection, where exogenous plasmid deoxyribonucleic acid (pDNA) is inserted into a stem cell using chemical, viral or physical methods. In this research, we used femtosecond (fs) laser pulses from a home-build microscope system to perforate the cellular membrane and allow entry of selected pDNA to alter the behaviour of mouse embryonic stem cells (mESCs). In one set of experiments, we induce fluorescence on mESCs using green fluorescence protein plasmid (pGFP) while in other tests; differentiation of mESCs into endoderm cells is performed using Sox-17 plasmid DNA (pSox-17). Primitive endoderm formation was thereafter confirmed using polymerase chain reactions (PCR) and the Sox-17 primer. Cell viability studies using adenosine triphosphate were also conducted. From the data, it was concluded that the photo-transfection method is biocompatible since it was able to induce fluorescence in mESCs. Secondly, it was confirmed that Sox-17 was photo-transfected successfully using 6 μW laser power, 128 fs pulses and 1kHz pulse repetition rate.

Coiled transmission line pulse generators

Science.gov (United States)

McDonald, Kenneth Fox

2010-11-09

Methods and apparatus are provided for fabricating and constructing solid dielectric "Coiled Transmission Line" pulse generators in radial or axial coiled geometries. The pour and cure fabrication process enables a wide variety of geometries and form factors. The volume between the conductors is filled with liquid blends of monomers, polymers, oligomers, and/or cross-linkers and dielectric powders; and then cured to form high field strength and high dielectric constant solid dielectric transmission lines that intrinsically produce ideal rectangular high voltage pulses when charged and switched into matched impedance loads. Voltage levels may be increased by Marx and/or Blumlein principles incorporating spark gap or, preferentially, solid state switches (such as optically triggered thyristors) which produce reliable, high repetition rate operation. Moreover, these Marxed pulse generators can be DC charged and do not require additional pulse forming circuitry, pulse forming lines, transformers, or an a high voltage spark gap output switch. The apparatus accommodates a wide range of voltages, impedances, pulse durations, pulse repetition rates, and duty cycles. The resulting mobile or flight platform friendly cylindrical geometric configuration is much more compact, light-weight, and robust than conventional linear geometries, or pulse generators constructed from conventional components. Installing additional circuitry may accommodate optional pulse shape improvements. The Coiled Transmission Lines can also be connected in parallel to decrease the impedance, or in series to increase the pulse length.

A 70 kV solid-state high voltage pulse generator based on saturable pulse transformer.

Science.gov (United States)

Fan, Xuliang; Liu, Jinliang

2014-02-01

High voltage pulse generators are widely applied in many fields. In recent years, solid-state and operating at repetitive mode are the most important developing trends of high voltage pulse generators. A solid-state high voltage pulse generator based on saturable pulse transformer is proposed in this paper. The proposed generator is consisted of three parts. They are charging system, triggering system, and the major loop. Saturable pulse transformer is the key component of the whole generator, which acts as a step-up transformer and main switch during working process of this generator. The circuit and working principles of the proposed pulse generator are introduced first in this paper, and the saturable pulse transformer used in this generator is introduced in detail. Circuit of the major loop is simulated to verify the design of the system. Demonstration experiments are carried out, and the results show that when the primary energy storage capacitor is charged to a high voltage, such as 2.5 kV, a voltage with amplitude of 86 kV can be achieved on the secondary winding. The magnetic core of saturable pulse transformer is saturated deeply and the saturable inductance of the secondary windings is very small. The switch function of the saturable pulse transformer can be realized ideally. Therefore, a 71 kV output voltage pulse is formed on the load. Moreover, the magnetic core of the saturable pulse transformer can be reset automatically.

High efficiency, monolithic fiber chirped pulse amplification system for high energy femtosecond pulse generation.

Science.gov (United States)

Peng, Xiang; Kim, Kyungbum; Mielke, Michael; Jennings, Stephen; Masor, Gordon; Stohl, Dave; Chavez-Pirson, Arturo; Nguyen, Dan T; Rhonehouse, Dan; Zong, Jie; Churin, Dmitriy; Peyghambarian, N

2013-10-21

A novel monolithic fiber-optic chirped pulse amplification (CPA) system for high energy, femtosecond pulse generation is proposed and experimentally demonstrated. By employing a high gain amplifier comprising merely 20 cm of high efficiency media (HEM) gain fiber, an optimal balance of output pulse energy, optical efficiency, and B-integral is achieved. The HEM amplifier is fabricated from erbium-doped phosphate glass fiber and yields gain of 1.443 dB/cm with slope efficiency >45%. We experimentally demonstrate near diffraction-limited beam quality and near transform-limited femtosecond pulse quality at 1.55 µm wavelength. With pulse energy >100 µJ and pulse duration of 636 fs (FWHM), the peak power is estimated to be ~160 MW. NAVAIR Public Release Distribution Statement A-"Approved for Public release; distribution is unlimited".

Magnetic Alignment of Pulsed Solenoids Using the Pulsed Wire Method

International Nuclear Information System (INIS)

Arbelaez, D.; Madur, A.; Lipton, T.M.; Waldron, W.L.; Kwan, J.W.

2011-01-01

A unique application of the pulsed-wire measurement method has been implemented for alignment of 2.5 T pulsed solenoid magnets. The magnetic axis measurement has been shown to have a resolution of better than 25 (micro)m. The accuracy of the technique allows for the identification of inherent field errors due to, for example, the winding layer transitions and the current leads. The alignment system is developed for the induction accelerator NDCX-II under construction at LBNL, an upgraded Neutralized Drift Compression experiment for research on warm dense matter and heavy ion fusion. Precise alignment is essential for NDCX-II, since the ion beam has a large energy spread associated with the rapid pulse compression such that misalignments lead to corkscrew deformation of the beam and reduced intensity at focus. The ability to align the magnetic axis of the pulsed solenoids to within 100 pm of the induction cell axis has been demonstrated.

Time Delayed Stage-Structured Predator-Prey Model with Birth Pulse and Pest Control Tactics

Directory of Open Access Journals (Sweden)

Mei Yan

2014-01-01

Full Text Available Normally, chemical pesticides kill not only pests but also their natural enemies. In order to better control the pests, two-time delayed stage-structured predator-prey models with birth pulse and pest control tactics are proposed and analyzed by using impulsive differential equations in present work. The stability threshold conditions for the mature prey-eradication periodic solutions of two models are derived, respectively. The effects of key parameters including killing efficiency rate, pulse period, the maximum birth effort per unit of time of natural enemy, and maturation time of prey on the threshold values are discussed in more detail. By comparing the two threshold values of mature prey-extinction, we provide the fact that the second control tactic is more effective than the first control method.

Few-cycle isolated attosecond pulses

International Nuclear Information System (INIS)

Sansone, G.; Benedetti, E.; Calegari, F.; Stagira, S.; Vozzi, C.; Silvestri De, S.; Nisoli, M.

2006-01-01

Complete test of publication follows. In the last few years the field of attosecond science has shown impressive and rapid progress, mainly due to the introduction of novel experimental methods for the characterization of extreme ultraviolet (XUV) pulses and attosecond electron wave packets. This development has been also triggered by significant improvements in the control of the electric field of the driving infrared pulses. Particularly interesting for the applications is the generation of isolated attosecond XUV pulses using few-cycle driving pulses. In this case significant progresses have been achieved thanks to the stabilization of the carrier-envelope phase (CEP) of amplified light pulses. In this work we demonstrate that the polarization gating (PG) method with few-cycle phase-stabilized driving pulses allows one to generate few-cycle isolated attosecond pulses tunable on a very broad spectral region. The PG method is based on temporal modulation of the ellipticity of a light pulse, which confines the XUV emission in the temporal gate where the polarization is close to linear. The time-dependent polarization of phase-stabilized sub-6-fs pulses, generated by the hollow fiber technique, has been obtained using two birefringent plates. It is possible to create a linear polarization gate, whose position is imposed by the intensity profile of the pulse whilst the emission time is linked to the CEP of the electric field. The pulses have been analyzed by using a flat-field spectrometer. Continuous XUV spectra, corresponding to the production of isolated attosecond pulses, have been generated for particular CEP values. Upon changing the rotation of the first plate it was possible to tune the XUV emission in a broad spectra range. We have then achieved a complete temporal characterization of the generated isolated attosecond pulses using frequency-resolved optical gating for complete reconstruction of attosecond bursts (FROG CRAB). The measured parabolic phase

Foundations of pulsed power technology

CERN Document Server

Lehr, Janet

2018-01-01

Pulsed power technologies could be an answer to many cutting-edge applications. The challenge is in how to develop this high-power/high-energy technology to fit current market demands of low-energy consuming applications. This book provides a comprehensive look at pulsed power technology and shows how it can be improved upon for the world of today and tomorrow. Foundations of Pulsed Power Technology focuses on the design and construction of the building blocks as well as their optimum assembly for synergetic high performance of the overall pulsed power system. Filled with numerous design examples throughout, the book offers chapter coverage on various subjects such as: Marx generators and Marx-like circuits; pulse transformers; pulse-forming lines; closing switches; opening switches; multi-gigawatt to multi-terawatt systems; energy storage in capacitor banks; electrical breakdown in gases; electrical breakdown in solids, liquids and vacuum; pulsed voltage and current measurements; electromagnetic interferen...

An 8-GW long-pulse generator based on Tesla transformer and pulse forming network.

Science.gov (United States)

Su, Jiancang; Zhang, Xibo; Li, Rui; Zhao, Liang; Sun, Xu; Wang, Limin; Zeng, Bo; Cheng, Jie; Wang, Ying; Peng, Jianchang; Song, Xiaoxin

2014-06-01

A long-pulse generator TPG700L based on a Tesla transformer and a series pulse forming network (PFN) is constructed to generate intense electron beams for the purpose of high power microwave (HPM) generation. The TPG700L mainly consists of a 12-stage PFN, a built-in Tesla transformer in a pulse forming line, a three-electrode gas switch, a transmission line with a trigger, and a load. The Tesla transformer and the compact PFN are the key technologies for the development of the TPG700L. This generator can output electrical pulses with a width as long as 200 ns at a level of 8 GW and a repetition rate of 50 Hz. When used to drive a relative backward wave oscillator for HPM generation, the electrical pulse width is about 100 ns on a voltage level of 520 kV. Factors affecting the pulse waveform of the TPG700L are also discussed. At present, the TPG700L performs well for long-pulse HPM generation in our laboratory.

An 8-GW long-pulse generator based on Tesla transformer and pulse forming network

Energy Technology Data Exchange (ETDEWEB)

Su, Jiancang; Zhang, Xibo; Li, Rui; Zhao, Liang, E-mail: zhaoliang0526@163.com; Sun, Xu; Wang, Limin; Zeng, Bo; Cheng, Jie; Wang, Ying; Peng, Jianchang; Song, Xiaoxin [Science and Technology on High Power Microwave Laboratory, Northwest Institute of Nuclear Technology, Xi' an, Shaanxi 710024 (China)

2014-06-15

A long-pulse generator TPG700L based on a Tesla transformer and a series pulse forming network (PFN) is constructed to generate intense electron beams for the purpose of high power microwave (HPM) generation. The TPG700L mainly consists of a 12-stage PFN, a built-in Tesla transformer in a pulse forming line, a three-electrode gas switch, a transmission line with a trigger, and a load. The Tesla transformer and the compact PFN are the key technologies for the development of the TPG700L. This generator can output electrical pulses with a width as long as 200 ns at a level of 8 GW and a repetition rate of 50 Hz. When used to drive a relative backward wave oscillator for HPM generation, the electrical pulse width is about 100 ns on a voltage level of 520 kV. Factors affecting the pulse waveform of the TPG700L are also discussed. At present, the TPG700L performs well for long-pulse HPM generation in our laboratory.

Pulse pile-up IV

International Nuclear Information System (INIS)

Wilkinson, D.H.

1991-05-01

The study of pulse pile-up is extended from the case of unipolar pulses, for which ruin theory is an excellent approximation, to the case of bipolar pulses for which ruin theory is not applicable to the effect of the back-kicks in reducing the pile-up: an appropriate solution is presented. (Author) 3 refs., 11 figs

Application of nonlinear pulse shaping of femtosecond pulse generation in a fiber amplifier at 500 MHz repetition rate

Science.gov (United States)

Liu, Yang; Luo, Daping; Wang, Chao; Zhu, Zhiwei; Li, Wenxue

2018-03-01

We numerically and experimentally demonstrate that a nonlinear pulse shaping technique based on pre-chirping management in a short gain fiber can be exploited to improve the quality of a compressed pulse. With prior tuning of the pulse chirp, the amplified pulse express different nonlinear propagating processes. A spectrum with s flat top and more smooth wings, showing a similariton feature, generates with the optimal initial pulse chirp, and the shortest pulses with minimal pulse pedestals are obtained. Experimental results show the ability of nonlinear pulse shaping to enhance the quality of compressed pulses, as theoretically expected.

Differential pulse voltammetric determination of methyl parathion based on multiwalled carbon nanotubes-poly(acrylamide) nanocomposite film modified electrode

Energy Technology Data Exchange (ETDEWEB)

Zeng, Yanbo [Department of Chemistry and Shanghai Key Laboratory of Green Chemistry and Chemical Process, East China Normal University, 3663 Zhongshan Road(N), Shanghai, 200062 (China); College of Biological, Chemical Sciences and Engineering, Jiaxing University, Jiaxing 314001 (China); Yu, Dajun; Yu, Yanyan [Department of Chemistry and Shanghai Key Laboratory of Green Chemistry and Chemical Process, East China Normal University, 3663 Zhongshan Road(N), Shanghai, 200062 (China); Zhou, Tianshu [Department of Environmental Science, East China Normal University, 3663 Zhongshan Road(N), Shanghai, 200062 (China); Shi, Guoyue, E-mail: gyshi@chem.ecnu.edu.cn [Department of Chemistry and Shanghai Key Laboratory of Green Chemistry and Chemical Process, East China Normal University, 3663 Zhongshan Road(N), Shanghai, 200062 (China)

2012-05-30

Highlights: Black-Right-Pointing-Pointer A sensitive electrochemical sensor for detecting methyl parathion in environmental samples. Black-Right-Pointing-Pointer The preparation, characterization and application of this novel MWCNTs-PAAM nanocomposite. Black-Right-Pointing-Pointer The MWCNTs-PAAM/GCE exhibited a high adsorption and strong affinity toward methyl parathion. Black-Right-Pointing-Pointer Wide linear range and low detection limit of the proposed method for detecting methyl parathion. - Abstract: A sensitive electrochemical differential pulse voltammetry method was developed for detecting methyl parathion based on multiwalled carbon nanotubes-poly(acrylamide) (MWCNTs-PAAM) nanocomposite film modified glassy carbon electrode. The novel MWCNTs-PAAM nanocomposite, containing high content of amide groups, was synthesized by PAAM polymerizing at the vinyl group functionalized MWCNTs surface using free radical polymerization. The MWCNTs-PAAM nanocomposite was characterized by Fourier transform infrared spectroscopy, thermal gravimetric analysis and scanning electron microscopy. Electrochemical behavior and interference studies of MWCNTs-PAAM/GCE for methyl parathion were investigated. The experimental results demonstrated that the MWCNTs-PAAM/GCE exhibited a high adsorption and strong affinity toward methyl parathion compared with some metal ions and nitroaromatic compounds, which exist in environmental samples. The adsorbed amount of methyl parathion on the MWCNTs-PAAM/GCE approached the equilibrium value upon 5 min adsorption time. A linear calibration curve for methyl parathion was obtained in the concentration range from 5.0 Multiplication-Sign 10{sup -9} to 1.0 Multiplication-Sign 10{sup -5} mol L{sup -1}, with a detection limit of 2.0 Multiplication-Sign 10{sup -9} mol L{sup -1}. The MWCNTs-PAAM/GCE was proved to be a suitable sensing tool for the fast, sensitive and selective determination of methyl parathion in environmental water samples.

Nanosecond bipolar pulse generators for bioelectrics.

Science.gov (United States)

Xiao, Shu; Zhou, Chunrong; Yang, Enbo; Rajulapati, Sambasiva R

2018-04-26

Biological effects caused by a nanosecond pulse, such as cell membrane permeabilization, peripheral nerve excitation and cell blebbing, can be reduced or cancelled by applying another pulse of reversed polarity. Depending on the degree of cancellation, the pulse interval of these two pulses can be as long as dozens of microseconds. The cancellation effect diminishes as the pulse duration increases. To study the cancellation effect and potentially utilize it in electrotherapy, nanosecond bipolar pulse generators must be made available. An overview of the generators is given in this paper. A pulse forming line (PFL) that is matched at one end and shorted at the other end allows a bipolar pulse to be produced, but no delay can be inserted between the phases. Another generator employs a combination of a resistor, an inductor and a capacitor to form an RLC resonant circuit so that a bipolar pulse with a decaying magnitude can be generated. A third generator is a converter, which converts an existing unipolar pulse to a bipolar pulse. This is done by inserting an inductor in a transmission line. The first phase of the bipolar pulse is provided by the unipolar pulse's rising phase. The second phase is formed during the fall time of the unipolar pulse, when the inductor, which was previously charged during the flat part of the unipolar pulse, discharges its current to the load. The fourth type of generator uses multiple MOSFET switches stacked to turn on a pre-charged, bipolar RC network. This approach is the most flexible in that it can generate multiphasic pulses that have different amplitudes, delays, and durations. However, it may not be suitable for producing short nanosecond pulses (<100 ns), whereas the PFL approach and the RLC approach with gas switches are used for this range. Thus, each generator has its own advantages and applicable range. Copyright © 2018 Elsevier B.V. All rights reserved.

Fissile and fertile nuclear material measurements using a new differential die-away self-interrogation technique

International Nuclear Information System (INIS)

Menlove, H.O.; Menlove, S.H.; Tobin, S.J.

2009-01-01

This paper presents a new technique for the measurement of fissile and fertile nuclear materials in spent fuel and plutonium-laden materials such as mixed oxide (MOX) fuel. The technique, called differential die-away self-interrogation, is similar to traditional differential die-away analysis, but it does not require a pulsed neutron generator or pulsed beam accelerator, and it can measure the fertile mass in addition to the fissile mass. The new method uses the spontaneous fission neutrons from 244 Cm in spent fuel and 240 Pu effective neutrons in MOX as the 'pulsed' neutron source, with an average of ∼2.7 neutrons per pulse. The time-correlated neutrons from the spontaneous fission and the subsequent induced fissions are analyzed as a function of time to determine the spontaneous fission rate, the induced fast-neutron fissions, and the induced thermal-neutron fissions. The fissile mass is determined from the induced thermal-neutron fissions that are produced by reflected thermal neutrons that originated from the spontaneous fission reaction. The sensitivity of the fissile mass measurement is enhanced by the use of two measurements, with and without a cadmium liner between the sample and a hydrogenous moderator that surrounds the sample. The fertile mass is determined from the multiplicity analysis of the neutrons detected soon after the initial triggering neutron is detected. The method obtains good sensitivity by the optimal design of two different neutron die-away regions: a short die-away for the neutron detector region and a longer die-away for the sample interrogation region.

Analysis and Recognition of Traditional Chinese Medicine Pulse Based on the Hilbert-Huang Transform and Random Forest in Patients with Coronary Heart Disease

Directory of Open Access Journals (Sweden)

Rui Guo

2015-01-01

Full Text Available Objective. This research provides objective and quantitative parameters of the traditional Chinese medicine (TCM pulse conditions for distinguishing between patients with the coronary heart disease (CHD and normal people by using the proposed classification approach based on Hilbert-Huang transform (HHT and random forest. Methods. The energy and the sample entropy features were extracted by applying the HHT to TCM pulse by treating these pulse signals as time series. By using the random forest classifier, the extracted two types of features and their combination were, respectively, used as input data to establish classification model. Results. Statistical results showed that there were significant differences in the pulse energy and sample entropy between the CHD group and the normal group. Moreover, the energy features, sample entropy features, and their combination were inputted as pulse feature vectors; the corresponding average recognition rates were 84%, 76.35%, and 90.21%, respectively. Conclusion. The proposed approach could be appropriately used to analyze pulses of patients with CHD, which can lay a foundation for research on objective and quantitative criteria on disease diagnosis or Zheng differentiation.

Analysis and Recognition of Traditional Chinese Medicine Pulse Based on the Hilbert-Huang Transform and Random Forest in Patients with Coronary Heart Disease

Science.gov (United States)

Wang, Yiqin; Yan, Hanxia; Yan, Jianjun; Yuan, Fengyin; Xu, Zhaoxia; Liu, Guoping; Xu, Wenjie

2015-01-01

Objective. This research provides objective and quantitative parameters of the traditional Chinese medicine (TCM) pulse conditions for distinguishing between patients with the coronary heart disease (CHD) and normal people by using the proposed classification approach based on Hilbert-Huang transform (HHT) and random forest. Methods. The energy and the sample entropy features were extracted by applying the HHT to TCM pulse by treating these pulse signals as time series. By using the random forest classifier, the extracted two types of features and their combination were, respectively, used as input data to establish classification model. Results. Statistical results showed that there were significant differences in the pulse energy and sample entropy between the CHD group and the normal group. Moreover, the energy features, sample entropy features, and their combination were inputted as pulse feature vectors; the corresponding average recognition rates were 84%, 76.35%, and 90.21%, respectively. Conclusion. The proposed approach could be appropriately used to analyze pulses of patients with CHD, which can lay a foundation for research on objective and quantitative criteria on disease diagnosis or Zheng differentiation. PMID:26180536

Industrial Applications of Pulsed Power Technology

Science.gov (United States)

Takaki, Koichi; Katsuki, Sunao

Recent progress of the industrial applications of pulsed power is reviewed in this paper. Repetitively operated pulsed power generators with a moderate peak power have been developed for industrial applications. These generators are reliable and low maintenance. Development of the pulsed power generators helps promote industrial applications of pulsed power for such things as food processing, medical treatment, water treatment, exhaust gas treatment, ozone generation, engine ignition, ion implantation and others. Here, industrial applications of pulsed power are classified by application for biological effects, for pulsed streamer discharges in gases, for pulsed discharges in liquid or liquid-mixture, and for bright radiation sources.

Linear induction accelerators made from pulse-line cavities with external pulse injection

International Nuclear Information System (INIS)

Smith, I.

1979-01-01

Two types of linear induction accelerator have been reported previously. In one, unidirectional voltage pulses are generated outside the accelerator and injected into the accelerator cavity modules, which contain ferromagnetic material to reduce energy losses in the form of currents induced, in parallel with the beam, in the cavity structure. In the other type, the accelerator cavity modules are themselves pulse-forming lines with energy storage and switches; parallel current losses are made zero by the use of circuits that generate bidirectional acceleration waveforms with a zero voltage-time integral. In a third type of design described here, the cavities are externally driven, and 100% efficient coupling of energy to the beam is obtained by designing the external pulse generators to produce bidirectional voltage waveforms with zero voltage-time integral. A design for such a pulse generator is described that is itself one hundred percent efficient and which is well suited to existing pulse power techniques. Two accelerator cavity designs are described that can couple the pulse from such a generator to the beam; one of these designs provides voltage doubling. Comparison is made between the accelerating gradients that can be obtained with this and the preceding types of induction accelerator

Frequency selectivity in pulse responses of Pt/poly(3-hexylthiophene-2,5-diyl/polyethylene oxide +Li+/Pt hetero-junction.

Directory of Open Access Journals (Sweden)

Fei Zeng

Full Text Available Pt/poly(3-hexylthiophene-2,5-diyl/polyethylene oxide + Li+/Pt hetero junctions were fabricated, and their pulse responses were studied. The direct current characteristics were not symmetric in the sweeping range of ±2 V. Negative differential resistance appeared in the input range of 0 to 2 V because of de-doping (or reduction in the side with the semiconductor layer. The device responded stably to a train of pulses with a fixed frequency. The inverse current after a pulse was related to the back-migrated ions. Importantly, the weight calculated based on the inverse current strength, was depressed during low-frequency stimulations but was potentiated during high-frequency stimulations when pulses were positive. Therefore, frequency selectivity was first observed in a semiconducting polymer/electrolyte hetero junction. Detailed analysis of the pulse response showed that the input frequency could modulate the timing of ion doping, de-doping, and re-doping at the semiconducting polymer/electrolyte interface, which then resulted in the frequency selectivity. Our study suggests that the simple redox process in semiconducting polymers can be modulated and used in signal handling or the simulation of bio-learning.

Saturation Detection-Based Blocking Scheme for Transformer Differential Protection

Directory of Open Access Journals (Sweden)

Byung Eun Lee

2014-07-01

Full Text Available This paper describes a current differential relay for transformer protection that operates in conjunction with a core saturation detection-based blocking algorithm. The differential current for the magnetic inrush or over-excitation has a point of inflection at the start and end of each saturation period of the transformer core. At these instants, discontinuities arise in the first-difference function of the differential current. The second- and third-difference functions convert the points of inflection into pulses, the magnitudes of which are large enough to detect core saturation. The blocking signal is activated if the third-difference of the differential current is larger than the threshold and is maintained for one cycle. In addition, a method to discriminate between transformer saturation and current transformer (CT saturation is included. The performance of the proposed blocking scheme was compared with that of a conventional harmonic blocking method. The test results indicate that the proposed scheme successfully discriminates internal faults even with CT saturation from the magnetic inrush, over-excitation, and external faults with CT saturation, and can significantly reduce the operating time delay of the relay.

Optimal filter bandwidth for pulse oximetry

Science.gov (United States)

Stuban, Norbert; Niwayama, Masatsugu

2012-10-01

Pulse oximeters contain one or more signal filtering stages between the photodiode and microcontroller. These filters are responsible for removing the noise while retaining the useful frequency components of the signal, thus improving the signal-to-noise ratio. The corner frequencies of these filters affect not only the noise level, but also the shape of the pulse signal. Narrow filter bandwidth effectively suppresses the noise; however, at the same time, it distorts the useful signal components by decreasing the harmonic content. In this paper, we investigated the influence of the filter bandwidth on the accuracy of pulse oximeters. We used a pulse oximeter tester device to produce stable, repetitive pulse waves with digitally adjustable R ratio and heart rate. We built a pulse oximeter and attached it to the tester device. The pulse oximeter digitized the current of its photodiode directly, without any analog signal conditioning. We varied the corner frequency of the low-pass filter in the pulse oximeter in the range of 0.66-15 Hz by software. For the tester device, the R ratio was set to R = 1.00, and the R ratio deviation measured by the pulse oximeter was monitored as a function of the corner frequency of the low-pass filter. The results revealed that lowering the corner frequency of the low-pass filter did not decrease the accuracy of the oxygen level measurements. The lowest possible value of the corner frequency of the low-pass filter is the fundamental frequency of the pulse signal. We concluded that the harmonics of the pulse signal do not contribute to the accuracy of pulse oximetry. The results achieved by the pulse oximeter tester were verified by human experiments, performed on five healthy subjects. The results of the human measurements confirmed that filtering out the harmonics of the pulse signal does not degrade the accuracy of pulse oximetry.

SLAC pulsed X-ray facility

Science.gov (United States)

Ipe, N. E.; McCall, R. C.; Baker, E. D.

1986-05-01

The Stanford Linear Accelerator Center (SLAC) operates a high energy (up to 33 GeV) linear accelerator delivering pulses up to a few microseconds wide. The pulsed nature of the electron beam creates problems in the detection and measurement of radiation both from the accelerator beam and the klystrons that provide the RF power for the accelerator. Hence, a pulsed X-ray facility has been built at SLAC mainly for the purpose of testing the response of different radiation detection instruments to pulsed radiation fields. The X-ray tube consists of an electron gun with a control grid. This provides a stream of pulsed electrons that can be accelerated towards a confined target-window. The window is made up of aluminum 0.051 cm (20 mils) thick, plated on the vacuum side with a layer of gold 0.0006 cm (1/4 mil) thick. The frequency of electron pulses can be varied by an internal pulser from 60 to 360 pulses per second with pulse widths of 360 ns to 5 ms. The pulse amplitude can be varied over a wide range of currents. An external pulser can be used to obtain other frequencies or special pulse shapes. The voltage across the gun can be varied from 0 to 100 kV. The major part of the X-ray tube is enclosed in a large walk-in-cabinet made of 1.9 cm (3/4 in) plywood and lined with 0.32 cm (1/8 in) lead to make a very versatile facility.

SLAC pulsed x-ray facility

International Nuclear Information System (INIS)

Ipe, N.E.; McCall, R.C.; Baker, E.D.

1986-05-01

The Stanford Linear Accelerator Center (SLAC) operates a high energy (up to 33 GeV) linear accelerator delivering pulses up to a few microseconds wide. The pulsed nature of the electron beam creates problems in the detection and measurement of radiation both from the accelerator beam and the klystrons that provide the rf power for the accelerator. Hence, a pulsed x-ray facility has been built at SLAC mainly for the purpose of testing the response of different radiation detection instruments to pulsed radiation fields. The x-ray tube consists of an electron gun with a control grid. This provides a stream of pulsed electrons that can be accelerated towards a confined target-window. The window is made up of aluminium 0.051 cm (20 mils) thick, plated on the vacuum side with a layer of gold 0.0006 cm (1/4 mil) thick. The frequency of electron pulses can be varied by an internal pulser from 60 to 360 pulses per second with pulse widths of 360 ns to 5 μs. The pulse amplitude can be varied over a wide range of currents. An external pulser can be used to obtain other frequencies or special pulse shapes. The voltage across the gun can be varied from 0 to 100 kV. The major part of the x-ray tube is enclosed in a large walk-in-cabinet made of 1.9 cm (3/4 in) plywood and lined with 0.32 cm (1/8 in) lead to make a very versatile facility. 3 refs., 5 figs

Effects of laser wavelengths and pulse energy ratio on the emission enhancement in dual pulse LIBS

International Nuclear Information System (INIS)

Ahmed, Rizwan; Iqbal, Javed; Baig, M Aslam

2015-01-01

We present new studies on the effects of laser wavelengths, pulse energy ratio and interpulse delay between two laser pulses in the collinear dual pulse configuration of laser-induced breakdown spectroscopy (LIBS) on an iron sample in air using the fundamental (1064 nm) and the second harmonics (532 nm) of Nd:YAG lasers. In the dual pulse LIBS, an optimum value of interpulse delay with an appropriate combination of laser wavelengths, and laser pulse energy ratio, yields a 30 times signal intensity enhancement in the neutral iron lines as compared with single pulse LIBS. A comparison in the spatial variations of electron temperature along the axis of the plume expansion in single and double pulse LIBS has also been studied. (letter)

Angle-resolving time-of-flight electron spectrometer for near-threshold precision measurements of differential cross sections of electron-impact excitation of atoms and molecules

International Nuclear Information System (INIS)

Lange, M.; Matsumoto, J.; Setiawan, A.; Panajotovic, R.; Harrison, J.; Lower, J. C. A.; Newman, D. S.; Mondal, S.; Buckman, S. J.

2008-01-01

This article presents a new type of low-energy crossed-beam electron spectrometer for measuring angular differential cross sections of electron-impact excitation of atomic and molecular targets. Designed for investigations at energies close to excitation thresholds, the spectrometer combines a pulsed electron beam with the time-of-flight technique to distinguish between scattering channels. A large-area, position-sensitive detector is used to offset the low average scattering rate resulting from the pulsing duty cycle, without sacrificing angular resolution. A total energy resolution better than 150 meV (full width at half maximum) at scattered energies of 0.5-3 eV is achieved by monochromating the electron beam prior to pulsing it. The results of a precision measurement of the differential cross section for electron-impact excitation of helium, at an energy of 22 eV, are used to assess the sensitivity and resolution of the spectrometer

Ultrashort X-ray pulse science

Energy Technology Data Exchange (ETDEWEB)

Chin, Alan Hap [Univ. of California, Berkeley, CA (US). Dept. of Physics; Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

1998-05-01

A variety of phenomena involves atomic motion on the femtosecond time-scale. These phenomena have been studied using ultrashort optical pulses, which indirectly probe atomic positions through changes in optical properties. Because x-rays can more directly probe atomic positions, ultrashort x-ray pulses are better suited for the study of ultrafast structural dynamics. One approach towards generating ultrashort x-ray pulses is by 90° Thomson scattering between terawatt laser pulses and relativistic electrons. Using this technique, the author generated ~ 300 fs, 30 keV (0.4 Å) x-ray pulses. These x-ray pulses are absolutely synchronized with ultrashort laser pulses, allowing femtosecond optical pump/x-ray probe experiments to be performed. Using the right-angle Thomson scattering x-ray source, the author performed time-resolved x-ray diffraction studies of laser-perturbated InSb. These experiments revealed a delayed onset of lattice expansion. This delay is due to the energy relaxation from a dense electron-hole plasma to the lattice. The dense electron-hole plasma first undergoes Auger recombination, which reduces the carrier concentration while maintaining energy content. Longitudinal-optic (LO) phonon emission then couples energy to the lattice. LO phonon decay into acoustic phonons, and acoustic phonon propagation then causes the growth of a thermally expanded layer. Source characterization is instrumental in utilizing ultrashort x-ray pulses in time-resolved x-ray spectroscopies. By measurement of the electron beam diameter at the generation point, the pulse duration of the Thomson scattered x-rays is determined. Analysis of the Thomson scattered x-ray beam properties also provides a novel means of electron bunch characterization. Although the pulse duration is inferred for the Thomson scattering x-ray source, direct measurement is required for other x-ray pulse sources. A method based on the laser-assisted photoelectric effect (LAPE) has been demonstrated as a

Ultrashort X-ray pulse science

International Nuclear Information System (INIS)

Chin, A.H.; Lawrence Berkeley National Lab., CA

1998-01-01

A variety of phenomena involves atomic motion on the femtosecond time-scale. These phenomena have been studied using ultrashort optical pulses, which indirectly probe atomic positions through changes in optical properties. Because x-rays can more directly probe atomic positions, ultrashort x-ray pulses are better suited for the study of ultrafast structural dynamics. One approach towards generating ultrashort x-ray pulses is by 90 o Thomson scattering between terawatt laser pulses and relativistic electrons. Using this technique, the author generated ∼ 300 fs, 30 keV (0.4 (angstrom)) x-ray pulses. These x-ray pulses are absolutely synchronized with ultrashort laser pulses, allowing femtosecond optical pump/x-ray probe experiments to be performed. Using the right-angle Thomson scattering x-ray source, the author performed time-resolved x-ray diffraction studies of laser-perturbated InSb. These experiments revealed a delayed onset of lattice expansion. This delay is due to the energy relaxation from a dense electron-hole plasma to the lattice. The dense electron-hole plasma first undergoes Auger recombination, which reduces the carrier concentration while maintaining energy content. Longitudinal-optic (LO) phonon emission then couples energy to the lattice. LO phonon decay into acoustic phonons, and acoustic phonon propagation then causes the growth of a thermally expanded layer. Source characterization is instrumental in utilizing ultrashort x-ray pulses in time-resolved x-ray spectroscopies. By measurement of the electron beam diameter at the generation point, the pulse duration of the Thomson scattered x-rays is determined. Analysis of the Thomson scattered x-ray beam properties also provides a novel means of electron bunch characterization. Although the pulse duration is inferred for the Thomson scattering x-ray source, direct measurement is required for other x-ray pulse sources. A method based on the laser-assisted photoelectric effect (LAPE) has been

Chronic fatigue syndrome and impaired peripheral pulse characteristics on orthostasis–a new potential diagnostic biomarker

International Nuclear Information System (INIS)

Allen, John; Murray, Alan; Di Maria, Costanzo; Newton, Julia L

2012-01-01

Autonomic nervous system dysfunction is frequently reported in chronic fatigue syndrome (CFS) with orthostatic intolerance, a common symptom that can be objectively assessed. The frequent finding of autonomic dysfunction and symptoms on standing has the potential to provide a diagnostic biomarker in chronic fatigue. In this study we explored the clinical value of non-invasive optical multi-site photoplethysmography (PPG) technology to assess cardiovascular responses to standing. Multi-site PPG pulses were collected from tissue pads of the ears, fingers and toes of 14 patients with CFS and 14 age-matched sedentary subjects using a measurement protocol of a 10 min baseline (subject supine) followed by 3 min of tilting on a tilt table (head-up to 70°). Percentage change in pulse timing (pulse transit time, PTTf) and pulse amplitude (AMP) at each site were calculated using beat-to-beat pulse wave analysis. A significant reduction in the overall pulse timing response to controlled standing was found for the CFS group (using summed absolute percentage change in PTTf for ear, finger and toe sites, median change of 26% for CFS and 37% for control with p = 0.002). There were no significant differences between subject groups for the AMP measure at any site. Changes in AMP with tilt were, however, weakly significantly and negatively correlated with fatigue severity (p < 0.05). Receiver operating characteristic (ROC) analysis of timing measures produced an area under the curve of 0.81. Experimental linear discriminant classification analysis comparing both timing and amplitude measures produced an overall diagnostic accuracy of 82%. Pulse wave abnormalities have been observed in CFS and represent a potential objective measure to help differentiate between CFS patients and healthy controls. (paper)

Pulse-width discriminators

International Nuclear Information System (INIS)

Budyashov, Yu.G.; Grebenyuk, V.M.; Zinov, V.G.

1978-01-01

A pulse duration discriminator is described which is intended for processing signals from multilayer scintillators. The basic elements of the scintillator are: an input gate, a current generator, an integrating capacitor, a Schmidt trigger and an anticoincidence circuit. The basic circuit of the discriminator and its time diagrams explaining its operating are given. The discriminator is based on microcircuits. Pulse duration discrimination threshold changes continuously from 20 to 100 ns, while its amplitude threshold changes within 20 to 100 mV. The temperature instability of discrimination thresholds (both in pulse width and in amplitude) is better than 0.1 per cent/deg C

A compact high-voltage pulse generator based on pulse transformer with closed magnetic core.

Science.gov (United States)

Zhang, Yu; Liu, Jinliang; Cheng, Xinbing; Bai, Guoqiang; Zhang, Hongbo; Feng, Jiahuai; Liang, Bo

2010-03-01

A compact high-voltage nanosecond pulse generator, based on a pulse transformer with a closed magnetic core, is presented in this paper. The pulse generator consists of a miniaturized pulse transformer, a curled parallel strip pulse forming line (PFL), a spark gap, and a matched load. The innovative design is characterized by the compact structure of the transformer and the curled strip PFL. A new structure of transformer windings was designed to keep good insulation and decrease distributed capacitance between turns of windings. A three-copper-strip structure was adopted to avoid asymmetric coupling of the curled strip PFL. When the 31 microF primary capacitor is charged to 2 kV, the pulse transformer can charge the PFL to 165 kV, and the 3.5 ohm matched load can deliver a high-voltage pulse with a duration of 9 ns, amplitude of 84 kV, and rise time of 5.1 ns. When the load is changed to 50 ohms, the output peak voltage of the generator can be 165 kV, the full width at half maximum is 68 ns, and the rise time is 6.5 ns.

Enhancement of beam pulse controllability for a single-pulse formation system of a cyclotron

International Nuclear Information System (INIS)

Kurashima, Satoshi; Miyawaki, Nobumasa; Kashiwagi, Hirotsugu; Okumura, Susumu; Taguchi, Mitsumasa; Fukuda, Mitsuhiro

2015-01-01

The single-pulse formation technique using a beam chopping system consisting of two types of high-voltage beam kickers was improved to enhance the quality and intensity of the single-pulse beam with a pulse interval over 1 μs at the Japan Atomic Energy Agency cyclotron facility. A contamination rate of neighboring beam bunches in the single-pulse beam was reduced to less than 0.1%. Long-term purification of the single pulse beam was guaranteed by the well-controlled magnetic field stabilization system for the cyclotron magnet. Reduction of the multi-turn extraction number for suppressing the neighboring beam bunch contamination was achieved by restriction of a beam phase width and precise optimization of a particle acceleration phase. In addition, the single-pulse beam intensity was increased by a factor of two or more by a combination of two types of beam bunchers using sinusoidal and saw-tooth voltage waveforms. Provision of the high quality intense single-pulse beam contributed to improve the accuracy of experiments for investigation of scintillation light time-profile and for neutron energy measurement by a time-of-flight method

Characterization of Mycoplasma hyosynoviae strains by amplified fragment length polymorphism analysis, pulsed-field gel electrophoresis and 16S ribosomal DNA sequencing

DEFF Research Database (Denmark)

Kokotovic, Branko; Friis, N.F.; Ahrens, Peter

2002-01-01

, were investigated by analysis of amplified fragment length polymorphisms of the Bgl II and Mfe I restriction sites and by pulsed-field gel electrophoresis of a Bss HII digest of chromosomal DNA. Both methods allowed unambiguous differentiation of the analysed strains and showed similar discriminatory...

Airborne differential absorption lidar system for water vapor investigations

Science.gov (United States)

Browell, E. V.; Carter, A. F.; Wilkerson, T. D.

1981-01-01

Range-resolved water vapor measurements using the differential-absorption lidar (DIAL) technique is described in detail. The system uses two independently tunable optically pumped lasers operating in the near infrared with laser pulses of less than 100 microseconds separation, to minimize concentration errors caused by atmospheric scattering. Water vapor concentration profiles are calculated for each measurement by a minicomputer, in real time. The work is needed in the study of atmospheric motion and thermodynamics as well as in forestry and agriculture problems.

Hyper dispersion pulse compressor for chirped pulse amplification systems

Science.gov (United States)

Barty, Christopher P. J.

2011-11-29

A grating pulse compressor configuration is introduced for increasing the optical dispersion for a given footprint and to make practical the application for chirped pulse amplification (CPA) to quasi-narrow bandwidth materials, such as Nd:YAG. The grating configurations often use cascaded pairs of gratings to increase angular dispersion an order of magnitude or more. Increased angular dispersion allows for decreased grating separation and a smaller compressor footprint.

Pulse duration discriminator

International Nuclear Information System (INIS)

Kosakovskij, L.F.

1980-01-01

Basic circuits of a discriminator for discrimination of pulses with the duration greater than the preset one, and of a multifunctional discriminator allowing to discriminate pulses with the duration greater (tsub(p)>tsub(s)) and lesser (tsub(p) tsub(s) and with the duration tsub(p) [ru

ELABORATION OF HIGH-VOLTAGE PULSE INSTALLATIONS AND PROVIDING THEIR OPERATION PROTECTIVE MEASURES

Directory of Open Access Journals (Sweden)

А. М. Hashimov

2016-01-01

Full Text Available The article presents design engineering methods for the high-voltage pulse installations of technological purpose for disinfection of drinking water, sewage, and edible liquids by high field micro- and nanosecond pulsing exposure. Designing potentialities are considered of the principal elements of the high-voltage part and the discharge circuit of the installations towards assuring the best efficient on-load utilization of the source energy and safe operation of the high-voltage equipment. The study shows that for disinfection of drinking water and sewage it is expedient to apply microsecond pulse actions causing the electrohydraulic effect in aqueous media with associated complex of physical processes (ultraviolet emission, generation of ozone and atomic oxygen, mechanical compression waves, etc. having detrimental effect on life activity of the microorganisms. In case of disinfecting edible liquids it is recommended to use the nanosecond pulses capable of straight permeating the biological cell nucleus, inactivating it. Meanwhile, the nutritive and biological values of the foodstuffs are saved and their organoleptic properties are improved. It is noted that in elaboration process of high-frequency pulse installations special consideration should be given to issues of the operating personnel safety discipline and securing conditions for the entire installation uninterrupted performance. With this objective in view the necessary requirements should be fulfilled on shielding the high- and low-voltage installation parts against high-frequency electromagnetic emissions registered by special differential sensors. Simultaneously, the abatement measures should be applied on the high-voltage equipment operational noise level. The authors offer a technique for noise abatement to admissible levels (lower than 80 dB A by means of coating the inside surface with shielded enclosure of densely-packed abutting sheets of porous electro-acoustic insulating

Effect of rising time of rectangular pulse on inactivation of staphylococcus aureus by pulsed electric field

Science.gov (United States)

Zhang, Ruobing; Liang, Dapeng; Zheng, Nanchen; Xiao, Jianfu; Mo, Mengbin; Li, Jing

2013-03-01

Pulsed electric field (PEF) is a novel non-thermal food processing technology that involves the electric discharge of high voltage short pulses through the food product. In PEF study, rectangular pulses are most commonly used for inactivating microorganisms. However, little information is available on the inactivation effect of rising time of rectangular pulse. In this paper, inactivation effects, electric field strength, treatment time and conductivity on staphylococcus aureus inactivation were investigated when the pulse rising time is reduced from 2.5 μs to 200 ns. Experimental results showed that inactivation effect of PEF increased with electric field strength, solution conductivity and treatment time. Rising time of the rectangular pulse had a significant effect on the inactivation of staphylococcus aureus. Rectangular pulses with a rising time of 200 ns had a better inactivation effect than that with 2 μs. In addition, temperature increase of the solution treated by pulses with 200 ns rising time was lower than that with 2 μs. In order to obtain a given inactivation effect, treatment time required for the rectangular pulse with 200 ns rise time was shorter than that with 2 μs.

Effect of rising time of rectangular pulse on inactivation of staphylococcus aureus by pulsed electric field

International Nuclear Information System (INIS)

Zhang, Ruobing; Liang, Dapeng; Xiao, Jianfu; Mo, Mengbin; Li, Jing; Zheng, Nanchen

2013-01-01

Pulsed electric field (PEF) is a novel non-thermal food processing technology that involves the electric discharge of high voltage short pulses through the food product. In PEF study, rectangular pulses are most commonly used for inactivating microorganisms. However, little information is available on the inactivation effect of rising time of rectangular pulse. In this paper, inactivation effects, electric field strength, treatment time and conductivity on staphylococcus aureus inactivation were investigated when the pulse rising time is reduced from 2.5 μs to 200 ns. Experimental results showed that inactivation effect of PEF increased with electric field strength, solution conductivity and treatment time. Rising time of the rectangular pulse had a significant effect on the inactivation of staphylococcus aureus. Rectangular pulses with a rising time of 200 ns had a better inactivation effect than that with 2 μs. In addition, temperature increase of the solution treated by pulses with 200 ns rising time was lower than that with 2 μs. In order to obtain a given inactivation effect, treatment time required for the rectangular pulse with 200 ns rise time was shorter than that with 2 μs.

Selective susceptibility to nanosecond pulsed electric field (nsPEF) across different human cell types.

Science.gov (United States)

Gianulis, Elena C; Labib, Chantelle; Saulis, Gintautas; Novickij, Vitalij; Pakhomova, Olga N; Pakhomov, Andrei G

2017-05-01

Tumor ablation by nanosecond pulsed electric fields (nsPEF) is an emerging therapeutic modality. We compared nsPEF cytotoxicity for human cell lines of cancerous (IMR-32, Hep G2, HT-1080, and HPAF-II) and non-cancerous origin (BJ and MRC-5) under strictly controlled and identical conditions. Adherent cells were uniformly treated by 300-ns PEF (0-2000 pulses, 1.8 kV/cm, 50 Hz) on indium tin oxide-covered glass coverslips, using the same media and serum. Cell survival plotted against the number of pulses displayed three distinct regions (initial resistivity, logarithmic survival decline, and residual resistivity) for all tested cell types, but with differences in LD 50 spanning as much as nearly 80-fold. The non-cancerous cells were less sensitive than IMR-32 neuroblastoma cells but more vulnerable than the other cancers tested. The cytotoxic efficiency showed no apparent correlation with cell or nuclear size, cell morphology, metabolism level, or the extent of membrane disruption by nsPEF. Increasing pulse duration to 9 µs (0.75 kV/cm, 5 Hz) produced a different selectivity pattern, suggesting that manipulation of PEF parameters can, at least for certain cancers, overcome their resistance to nsPEF ablation. Identifying mechanisms and cell markers of differential nsPEF susceptibility will critically contribute to the proper choice and outcome of nsPEF ablation therapies.

Free radical reactions of hematoporphyrin: a pulse radiolysis study

International Nuclear Information System (INIS)

Ahmed, Mohammed; Guleria, Apurav; Singh, Ajay K.; Sarkar, S.K.

2011-01-01

Radiation chemistry of porphyrin derivatives has been given much attention in recent years. Although till date photo dynamic therapy (PDT) with Hematoporphyrin (HP) has already proved its effectiveness in the treatment of cancer, the molecular mechanisms by which this therapy-destroys tumour cells as well as its optimal physical parameters are still not fully understood. Thus it becomes necessary to understand the interaction of different free radicals with HP. Pulse radiolysis studies have been performed to understand the interaction of different free radicals with HP. The product formation along with bleaching and presence of a number of transients makes it difficult to pin point the mode and site of free radical attack. The radiation-induced formation of various transients (HP-OH, HO - , HP + ) in aqueous solution was investigated at various pHs by pulse radiolysis technique by means of N 3 , O - and CCl 3 O 2 radicals with and without triethyl-amine, under different dose conditions. The observed intermediates are characterized by their kinetic and spectroscopic data. The absorption spectrum of each transient could be differentiated from each other by their absorption maxima, extinction coefficients and kinetics. A clear indication of product formation has also been observed by employing continuous electron pulse and the solution shows a green coloration. It is conceivable that under certain conditions, similar transients may be produced when HP is used as a sensitizer in radiation chemotherapy of cancer patients. Our study may throw some light into the breakdown mechanism of haemoglobin to BV in addition to the understanding of free radical interaction of HP. (author)

Pile-up and defective pulse rejection by pulse shape discrimination in surface barrier detectors

International Nuclear Information System (INIS)

Sjoeland, K.A.; Kristiansson, P.

1994-01-01

A technique to reject pile-up pulses and defective tail pulses from surface barrier detectors by the use of pulse shape discrimination is demonstrated. The electronic implementation of the pulse shape discrimination is based upon the zero crossing technique and for data reduction multiparameter techniques are used. The characteristic τ value for pile-up rejection is shown to be less than 56 ns. Its effect on detection limits from tail reduction in Particle Elastic Scattering Analysis (PESA) and pile-up peak suppression is discussed. ((orig.))

Interaction of ultrashort laser pulses and silicon solar cells under short circuit conditions

Energy Technology Data Exchange (ETDEWEB)

Mundus, M., E-mail: markus.mundus@ise.fraunhofer.de; Giesecke, J. A.; Fischer, P.; Hohl-Ebinger, J.; Warta, W. [Fraunhofer Institute for Solar Energy Systems (ISE), Heidenhofstraße 2, 79110 Freiburg (Germany)

2015-02-28

Ultrashort pulse lasers are promising tools for numerous measurement purposes. Among other benefits their high peak powers allow for efficient generation of wavelengths in broad spectral ranges and at spectral powers that are orders of magnitude higher than in conventional light sources. Very recently this has been exploited for the establishment of sophisticated measurement facilities for electrical characterization of photovoltaic (PV) devices. As the high peak powers of ultrashort pulses promote nonlinear optical effects they might also give rise to nonlinear interactions with the devices under test that possibly manipulate the measurement outcome. In this paper, we present a comprehensive theoretical and experimental study of the nonlinearities affecting short circuit current (I{sub SC}) measurements of silicon (Si) solar cells. We derive a set of coupled differential equations describing the radiation-device interaction and discuss the nonlinearities incorporated in those. By a semi-analytical approach introducing a quasi-steady-state approximation and integrating a Green's function we solve the system of equations and obtain simulated I{sub SC} values. We validate the theoretical model by I{sub SC} ratios obtained from a double ring resonator setup capable for reproducible generation of various ultrashort pulse trains. Finally, we apply the model to conduct the most prominent comparison of I{sub SC} generated by ultrashort pulses versus continuous illumination. We conclude by the important finding that the nonlinearities induced by ultrashort pulses are negligible for the most common I{sub SC} measurements. However, we also find that more specialized measurements (e.g., of concentrating PV or Si-multijunction devices as well as highly localized electrical characterizations) will be biased by two-photon-absorption distorting the I{sub SC} measurement.

The interaction of intense subpicosecond laser pulses with underdense plasmas

Energy Technology Data Exchange (ETDEWEB)

Coverdale, Christine Ann [Univ. of California, Davis, CA (United States)

1995-05-11

Laser-plasma interactions have been of interest for many years not only from a basic physics standpoint, but also for their relevance to numerous applications. Advances in laser technology in recent years have resulted in compact laser systems capable of generating (psec), 10¹⁶ W/cm² laser pulses. These lasers have provided a new regime in which to study laser-plasma interactions, a regime characterized by L_plasma ≥ 2L_Rayleigh > cτ. The goal of this dissertation is to experimentally characterize the interaction of a short pulse, high intensity laser with an underdense plasma (n_o ≤ 0.05n_cr). Specifically, the parametric instability known as stimulated Raman scatter (SRS) is investigated to determine its behavior when driven by a short, intense laser pulse. Both the forward Raman scatter instability and backscattered Raman instability are studied. The coupled partial differential equations which describe the growth of SRS are reviewed and solved for typical experimental laser and plasma parameters. This solution shows the growth of the waves (electron plasma and scattered light) generated via stimulated Raman scatter. The dispersion relation is also derived and solved for experimentally accessible parameters. The solution of the dispersion relation is used to predict where (in k-space) and at what frequency (in ω-space) the instability will grow. Both the nonrelativistic and relativistic regimes of the instability are considered.

Sequentially pulsed traveling wave accelerator

Science.gov (United States)

Caporaso, George J [Livermore, CA; Nelson, Scott D [Patterson, CA; Poole, Brian R [Tracy, CA

2009-08-18

A sequentially pulsed traveling wave compact accelerator having two or more pulse forming lines each with a switch for producing a short acceleration pulse along a short length of a beam tube, and a trigger mechanism for sequentially triggering the switches so that a traveling axial electric field is produced along the beam tube in synchronism with an axially traversing pulsed beam of charged particles to serially impart energy to the particle beam.

Assessment and mitigation of electromagnetic pulse (EMP) impacts at short-pulse laser facilities

International Nuclear Information System (INIS)

Brown, C G Jr; Bond, E; Clancy, T; Dangi, S; Eder, D C; Ferguson, W; Kimbrough, J; Throop, A

2010-01-01

The National Ignition Facility (NIF) will be impacted by electromagnetic pulse (EMP) during normal long-pulse operation, but the largest impacts are expected during short-pulse operation utilizing the Advanced Radiographic Capability (ARC). Without mitigation these impacts could range from data corruption to hardware damage. We describe our EMP measurement systems on Titan and NIF and present some preliminary results and thoughts on mitigation.

Dose rate effect on micronuclei induction in human blood lymphocytes exposed to single pulse and multiple pulses of electrons.

Science.gov (United States)

Acharya, Santhosh; Bhat, N N; Joseph, Praveen; Sanjeev, Ganesh; Sreedevi, B; Narayana, Y

2011-05-01

The effects of single pulses and multiple pulses of 7 MV electrons on micronuclei (MN) induction in cytokinesis-blocked human peripheral blood lymphocytes (PBLs) were investigated over a wide range of dose rates per pulse (instantaneous dose rate). PBLs were exposed to graded doses of 2, 3, 4, 6, and 8 Gy of single electron pulses of varying pulse widths at different dose rates per pulse, ranging from 1 × 10(6) Gy s(-1) to 3.2 × 10(8) Gy s(-1). Different dose rates per pulse were achieved by changing the dose per electron pulse by adjusting the beam current and pulse width. MN yields per unit absorbed dose after irradiation with single electron pulses were compared with those of multiple pulses of electrons. A significant decrease in the MN yield with increasing dose rates per pulse was observed, when dose was delivered by a single electron pulse. However, no reduction in the MN yield was observed when dose was delivered by multiple pulses of electrons. The decrease in the yield at high dose rates per pulse suggests possible radical recombination, which leads to decreased biological damage. Cellular response to the presence of very large numbers of chromosomal breaks may also alter the damage.

Rapid thermal pulse annealing

International Nuclear Information System (INIS)

Miller, M.G.; Koehn, B.W.; Chaplin, R.L.

1976-01-01

Characteristics of recovery processes have been investigated for cases of heating a sample to successively higher temperatures by means of isochronal annealing or by using a rapid pulse annealing. A recovery spectra shows the same features independent of which annealing procedure is used. In order to determine which technique provides the best resolution, a study was made of how two independent first-order processes are separated for different heating rates and time increments of the annealing pulses. It is shown that the pulse anneal method offers definite advantages over isochronal annealing when annealing for short time increments. Experimental data by means of the pulse anneal techniques are given for the various substages of stage I of aluminium. (author)

Linear transformer driver for pulse generation

Science.gov (United States)

Kim, Alexander A; Mazarakis, Michael G; Sinebryukhov, Vadim A; Volkov, Sergey N; Kondratiev, Sergey S; Alexeenko, Vitaly M; Bayol, Frederic; Demol, Gauthier; Stygar, William A

2015-04-07

A linear transformer driver includes at least one ferrite ring positioned to accept a load. The linear transformer driver also includes a first power delivery module that includes a first charge storage devices and a first switch. The first power delivery module sends a first energy in the form of a first pulse to the load. The linear transformer driver also includes a second power delivery module including a second charge storage device and a second switch. The second power delivery module sends a second energy in the form of a second pulse to the load. The second pulse has a frequency that is approximately three times the frequency of the first pulse. The at least one ferrite ring is positioned to force the first pulse and the second pulse to the load by temporarily isolating the first pulse and the second pulse from an electrical ground.

Harmonic generation with a dual frequency pulse.

Science.gov (United States)

Keravnou, Christina P; Averkiou, Michalakis A

2014-05-01

Nonlinear imaging was implemented in commercial ultrasound systems over the last 15 years offering major advantages in many clinical applications. In this work, pulsing schemes coupled with a dual frequency pulse are presented. The pulsing schemes considered were pulse inversion, power modulation, and power modulated pulse inversion. The pulse contains a fundamental frequency f and a specified amount of its second harmonic 2f. The advantages and limitations of this method were evaluated with both acoustic measurements of harmonic generation and theoretical simulations based on the KZK equation. The use of two frequencies in a pulse results in the generation of the sum and difference frequency components in addition to the other harmonic components. While with single frequency pulses, only power modulation and power modulated pulse inversion contained odd harmonic components, with the dual frequency pulse, pulse inversion now also contains odd harmonic components.

New neutron imaging using pulsed sources. Characteristics of a pulsed neutron source and principle of pulsed neutron imaging

International Nuclear Information System (INIS)

Kiyanagi, Yoshiaki

2012-01-01

Neutron beam is one of important tools to obtain the transmission image of an object. Until now, steady state neutron sources such as reactors are mainly used for this imaging purpose. Recently, it has been demonstrated that pulsed neutron imaging based on accelerator neutron sources can provide a real-space distribution of physical information of materials such as crystallographic structure, element, temperature, hydrogen bound state, magnetic field and so on, by analyzing wavelength dependent transmission spectrum, which information cannot be observed or difficult to obtain with a traditional imaging method using steady state neutrons. Here, characteristics of the pulsed neutron source and principle of the pulsed neutron imaging are explained as a basic concept of the new method. (author)

Development of ultra-short high voltage pulse technology using magnetic pulse compression

Energy Technology Data Exchange (ETDEWEB)

Cha, Byung Heon; Kim, S. G.; Nam, S. M.; Lee, B. C.; Lee, S. M.; Jeong, Y. U.; Cho, S. O.; Jin, J. T.; Choi, H. L

1998-01-01

The control circuit for high voltage switches, the saturable inductor for magnetic assist, and the magnetic pulse compression circuit were designed, constructed, and tested. The core materials of saturable inductors in magnetic pulse compression circuit were amorphous metal and ferrite and total compression stages were 3. By the test, in high repetition rate, high pulse compression were certified. As a result of this test, it became possible to increase life-time of thyratrons and to replace thyratrons by solid-state semiconductor switches. (author). 16 refs., 16 tabs.

Development of ultra-short high voltage pulse technology using magnetic pulse compression

International Nuclear Information System (INIS)

Cha, Byung Heon; Kim, S. G.; Nam, S. M.; Lee, B. C.; Lee, S. M.; Jeong, Y. U.; Cho, S. O.; Jin, J. T.; Choi, H. L.

1998-01-01

The control circuit for high voltage switches, the saturable inductor for magnetic assist, and the magnetic pulse compression circuit were designed, constructed, and tested. The core materials of saturable inductors in magnetic pulse compression circuit were amorphous metal and ferrite and total compression stages were 3. By the test, in high repetition rate, high pulse compression were certified. As a result of this test, it became possible to increase life-time of thyratrons and to replace thyratrons by solid-state semiconductor switches. (author). 16 refs., 16 tabs

<3> OMEGA pulse-forming network

CERN Multimedia

1974-01-01

Adjustement of the 3 W pulse-forming network of the SPS beam dumping system. When charged at 60 kV, this PFN gives 10 kA, 25 ms current pulses, with oscillations, superimposed on the pulse flat top, of an amplitude of +/- 1 Ka.

Software emulator of nuclear pulse generation with different pulse shapes and pile-up

Energy Technology Data Exchange (ETDEWEB)

Pechousek, Jiri, E-mail: jiri.pechousek@upol.cz [Department of Experimental Physics, Faculty of Science, Palacky University, 17. listopadu 1192/12, 771 46 Olomouc (Czech Republic); Konecny, Daniel [Department of Optics, Faculty of Science, Palacky University, 17. listopadu 1192/12, 77 146 Olomouc (Czech Republic); Novak, Petr; Kouril, Lukas; Kohout, Pavel [Department of Experimental Physics, Faculty of Science, Palacky University, 17. listopadu 1192/12, 771 46 Olomouc (Czech Republic); Celiktas, Cuneyt [Department of Physics, Faculty of Science, Ege University, Bornova, Izmir (Turkey); Vujtek, Milan [Department of Experimental Physics, Faculty of Science, Palacky University, 17. listopadu 1192/12, 771 46 Olomouc (Czech Republic)

2016-08-21

The optimal detection of output signals from nuclear counting devices represents one of the key physical factors that govern accuracy and experimental reproducibility. In this context, the fine calibration of the detector under diverse experimental scenarios, although time costly, is necessary. However this process can be rendered easier with the use of systems that work in lieu of emulators. In this report we describe an innovative programmable pulse generator device capable to emulate the scintillation detector signals, in a way to mimic the detector performances under a variety of experimental conditions. The emulator generates a defined number of pulses, with a given shape and amplitude in the form of a sampled detector signal. The emulator output is then used off-line by a spectrometric system in order to set up its optimal performance. Three types of pulse shapes are produced by our device, with the possibility to add noise and pulse pile-up effects into the signal. The efficiency of the pulse detection, pile-up rejection and/or correction, together with the dead-time of the system, are therein analyzed through the use of some specific algorithms for pulse processing, and the results obtained validate the beneficial use of emulators for the accurate calibration process of spectrometric systems.

LIF inhibits osteoblast differentiation at least in part by regulation of HAS2 and its product hyaluronan.

Science.gov (United States)

Falconi, Dominic; Aubin, Jane E

2007-08-01

LIF arrests osteogenesis in fetal rat calvaria cells in a differentiation stage-specific manner. Differential display identified HAS2 as a LIF-induced gene and its product, HA, modulated osteoblast differentiation similarly to LIF. Our data suggest that LIF arrests osteoblast differentiation by altering HA content of the extracellular matrix. Leukemia inhibitory factor (LIF) elicits both anabolic and catabolic effects on bone. We previously showed in the fetal rat calvaria (RC) cell system that LIF inhibits osteoblast differentiation at the late osteoprogenitor/early osteoblast stage. To uncover potential molecular mediators of this inhibitory activity, we used a positive-negative genome-wide differential display screen to identify LIF-induced changes in the developing osteoblast transcriptome. Although LIF signaling is active throughout the RC cell proliferation-differentiation sequence, only a relatively small number of genes, in several different functional clusters, are modulated by LIF specifically during the LIF-sensitive inhibitory time window. Based on their known and predicted functions, most of the LIF-regulated genes identified are plausible candidates to be involved in the LIF-induced arrest of osteoprogenitor differentiation. To test this hypothesis, we further analyzed the function of one of the genes identified, hyaluronan synthase 2 (HAS2), in the LIF-induced inhibition. Synthesis of hyaluronan (HA), the product of HAS enzymatic activity, was stimulated by LIF and mimicked the HAS2 expression profile, with highest expression in early/proliferative and late/maturing cultures and lowest levels in intermediate/late osteoprogenitor-early osteoblast cultures. Exogenously added high molecular weight HA, the product of HAS2, dose-dependently inhibited osteoblast differentiation, with pulse-treatment effective in the same differentiation stage-specific inhibitory window as seen with LIF. In addition, however, pulse treatment with HA in early cultures

Supercoherent phenomena in pulsed power

International Nuclear Information System (INIS)

O'Rourke, R.C.

1983-01-01

This chapter proposes the formulation of programs of basic physics research to transform Pulsed Power Technology (PPT) to Pulsed Power Science and Technology (PPS and T) by formulating the laws of the quantized microscopic electromagnetic field; applying the microscopic electromagnetic field theory to the generation, propagation and deposition of pulses in nonlinear networks; learning more about the basic super coherent ''micro-structure'' in space and time of the many-photon states of pulsed laser beams; learning more about the basic super coherent ''micro-structure'' in space and time of the many-electronstates of pulsed electron and ion laser beams; and learning everything about the ''micro-picture'' of so-called ''dielectric breakdown'' and the associated absolute time delays. Promotes the idea that laser, electron and ion beams are similar kinds of pulses in the microscopic electromagnetic field. Presents expression for the microscopic electromagnetic field in order to show the role of supercoherence in PPS and T

Pulse plating

CERN Document Server

Hansal, Wolfgang E G; Green, Todd; Leisner, Peter; Reichenbach, Andreas

2012-01-01

The electrodeposition of metals using pulsed current has achieved practical importance in recent years. Although it has long been known that changes in potential, with or without polarity reversal, can significantly affect the deposition process, the practical application of this has been slow to be adopted. This can largely be explained in terms of the complex relationship between the current regime and its effect on the electrodeposition process. In order to harness these effects, an understanding of the anodic and cathodic electrochemical processes is necessary, together with the effects of polarity reversal and the rate of such reversals. In this new monograph, the basics of metal electrodeposition from solution are laid out in great detail in seven distinct chapters. With this knowledge, the reader is able to predict how a given pulse train profile can be adopted to achieve a desired outcome. Equally important is the choice of a suitable rectifier and the ancillary control circuits to enable pulse platin...

Laser-pulsed relativistic electron gun

International Nuclear Information System (INIS)

Sherman, N.K.

1986-01-01

A relativistic (β ≅ 0.8) electron gun with good emittance and subnanosecond pulse duration which can be synchronized to picosecond laser pulses is being developed at NRC for use in studies of particle acceleration by lasers. Bursts of electron pulses exceeding 280 keV in energy have been extracted into air form a laser-driven vacuum photodiode. Trains of 5 ps pulses of ultraviolet UV light illuminate a magnesium cathode. Photoelectrons emitted from the cathode are accelerated in a graded electrostatic potential set up by a 360 kV Marx-generator. The UV pulses are obtained by doubling the frequency of a 606 nm dye laser modelocked at 160 MHz. Electron energies were measured by residual range in an echelon of Al foils. Total charge per burst was measured by picoammeter. Time structure of the bursts has been examined with plastic scintillator and a fast photomultiplier. Tests on a low voltage photodiode achieved a current density of 180 A/cm/sup 2/ from an Mg cathode, with quantum efficiency of 2.4 x 10/sup -6/ electron per UV photon. The brevity and intensity of the laser pulses cause the electric charge collected per pulse to increase linearly with bias voltage rather than according to the Langmuir-Child law. Gun emittance is about 150 mm-msr and beam brightness is about 1A/cm/sup 2/-sr. Estimated duration of individual electron pulses of a burst is about 400 ps with instantaneous current of about 0.1 mA. Energy spread within one pulse is expected to be about 15%. This gun has the potential to be a useful source of relativistic electrons for laser acceleration studies

System for increasing laser pulse rate

International Nuclear Information System (INIS)

1980-01-01

A technique of static elements is disclosed for combining a plurality of laser beams having time sequenced, pulsed radiation to achieve an augmented pulse rate. The technique may also be applied in a system for combining both time sequenced pulses and frequency distinct pulses for use in a system for isotope enrichment. (author)

Pulsed irradiation of enriched UO{sub 2} in the Annular Core Pulse Reactor (ACPR)

Energy Technology Data Exchange (ETDEWEB)

Schmidt, T R; Lucoff, D M; Reil, K O; Croucher, D W [Sandia Laboratories (United States)

1974-07-01

A series of experiments have been conducted in the Annular Core Pulse Reactor (ACPR) to determine the energy deposition and behavior of enriched UO{sub 2} under pulse conditions. In the experiment single unirradiated pellets with enrichments up to 25 percent were pulse heated to melt temperatures. Temperature and fission product inventory measurements were made and compared with neutron transport calculations. (author)

Pulsed neutron generator

International Nuclear Information System (INIS)

Bespalov, D.F.; Bykovskii, Yu.A.; Vergun, I.I.; Kozlovskii, K.I.; Kozyrev, Yu.P.; Leonov, R.K.; Simagin, B.I.; Tsybin, A.S.; Shikanov, A.Ie.

1986-03-01

The paper describes a new device for generating pulsed neutron fields, utilized in nuclear geophysics for carrying out pulsed neutron logging and activation analysis under field conditions. The invention employs a sealed-off neutron tube with a laser ion source which increases neutron yield to the level of 10 neutrons per second or higher. 2 refs., 1 fig

Coaxial pulse matching transformer

International Nuclear Information System (INIS)

Ledenev, V.V.; Khimenko, L.T.

1986-01-01

This paper describes a coaxial pulse matching transformer with comparatively simple design, increased mechanical strength, and low stray inductance. The transformer design makes it easy to change the turns ratio. The circuit of the device and an expression for the current multiplication factor are presented; experiments confirm the efficiency of the transformer. Apparatus with a coaxial transformer for producing high-power pulsed magnetic fields is designed (current pulses of 1-10 MA into a load and a natural frequency of 100 kHz)

Polarography-past, present, and future

Czech Academy of Sciences Publication Activity Database

Heyrovský, Michael

2011-01-01

Roč. 15, 7-8 (2011), s. 1799-1803 ISSN 1432-8488 Institutional research plan: CEZ:AV0Z40400503 Keywords : Chronopotentiometry * Current-controlled electrolysis * Drop ping mercury electrode Subject RIV: CG - Electrochemistry Impact factor: 2.131, year: 2011

Low power arcjet thruster pulse ignition

Science.gov (United States)

Sarmiento, Charles J.; Gruber, Robert P.

1987-01-01

An investigation of the pulse ignition characteristics of a 1 kW class arcjet using an inductive energy storage pulse generator with a pulse width modulated power converter identified several thruster and pulse generator parameters that influence breakdown voltage including pulse generator rate of voltage rise. This work was conducted with an arcjet tested on hydrogen-nitrogen gas mixtures to simulate fully decomposed hydrazine. Over all ranges of thruster and pulser parameters investigated, the mean breakdown voltages varied from 1.4 to 2.7 kV. Ignition tests at elevated thruster temperatures under certain conditions revealed occasional breakdowns to thruster voltages higher than the power converter output voltage. These post breakdown discharges sometimes failed to transition to the lower voltage arc discharge mode and the thruster would not ignite. Under the same conditions, a transition to the arc mode would occur for a subsequent pulse and the thruster would ignite. An automated 11 600 cycle starting and transition to steady state test demonstrated ignition on the first pulse and required application of a second pulse only two times to initiate breakdown.

Device for flattening statistically distributed pulses

International Nuclear Information System (INIS)

Il'kanaev, G.I.; Iskenderov, V.G.; Rudnev, O.V.; Teller, V.S.

1976-01-01

The description is given of a device that converts the series of statistically distributed pulses into a pseudo-uniform one. The inlet pulses switch over the first counter, and the second one is switched over by the clock pulses each time the uniformity of the counters' states is violated. This violation is recorded by the logic circuit which passes to the output the clock pulses in the amount equal to that of the pulses that reached the device inlet. Losses at the correlation between the light velocity and the sampling rate up to 0.3 do not exceed 0.7 per cent for the memory of pulse counters 3, and 0.035 per cent for memory 7

Simulation of neutrons and gamma pulse signal and research on the pulse shape discrimination technology

International Nuclear Information System (INIS)

Zuo Guangxia; He Bin; Xu Peng; Qiu Xiaolin; Ma Wenyan; Li Sufen

2012-01-01

In neutrons detection, it is important to discriminate the neutron signals from the gamma-ray background. In this article, simulation of neutrons and gamma pulse signals is developed based on the LabVIEW platform. Two digital algorithms of the charge comparison method and the pulse duration time method are realized using 10000 simulation signals. Experimental results show that neutron and gamma pulse signals can be discriminated by the two methods, and the pulse duration time method is better than the charge comparison method. (authors)

IAE pulsed electrostatic accelerator

International Nuclear Information System (INIS)

Afanas'ev, V.P.; Ganzhelyuk, M.L.; Kozlov, L.D.; Koltypin, E.A.; Molchanov, Yu.D.; Otroshchenko, G.A.; Yan'kov, G.B.

1976-01-01

The modernized pulse electrostatic accelerator using the klystron ion grouping and the beam interruption system prior to acceleration is described. The accelerator is modernized in order to improve parameters of a current pulse and to decrease the background in the measurement room. The ion beam of needed dimensions is obtained with the help of a high-frequency source and a beam grouping and deflection system. The general view of the beam grouping and deflection system is shown. The ion beam forming process is considered in detail. The modernized electrostatic accelerator permits to obtain a pulse current with a pulse length of 1.5 ns and an amplitude of 1.5 - 2 μA. With the repetition frequency of 2 MHz, the average target current is about 6 μA

Square pulse linear transformer driver

Directory of Open Access Journals (Sweden)

A. A. Kim

2012-04-01

Full Text Available The linear transformer driver (LTD technological approach can result in relatively compact devices that can deliver fast, high current, and high-voltage pulses straight out of the LTD cavity without any complicated pulse forming and pulse compression network. Through multistage inductively insulated voltage adders, the output pulse, increased in voltage amplitude, can be applied directly to the load. The usual LTD architecture [A. A. Kim, M. G. Mazarakis, V. A. Sinebryukhov, B. M. Kovalchuk, V. A. Vizir, S. N Volkov, F. Bayol, A. N. Bastrikov, V. G. Durakov, S. V. Frolov, V. M. Alexeenko, D. H. McDaniel, W. E. Fowler, K. LeCheen, C. Olson, W. A. Stygar, K. W. Struve, J. Porter, and R. M. Gilgenbach, Phys. Rev. ST Accel. Beams 12, 050402 (2009PRABFM1098-440210.1103/PhysRevSTAB.12.050402; M. G. Mazarakis, W. E. Fowler, A. A. Kim, V. A. Sinebryukhov, S. T. Rogowski, R. A. Sharpe, D. H. McDaniel, C. L. Olson, J. L. Porter, K. W. Struve, W. A. Stygar, and J. R. Woodworth, Phys. Rev. ST Accel. Beams 12, 050401 (2009PRABFM1098-440210.1103/PhysRevSTAB.12.050401] provides sine shaped output pulses that may not be well suited for some applications like z-pinch drivers, flash radiography, high power microwaves, etc. A more suitable power pulse would have a flat or trapezoidal (rising or falling top. In this paper, we present the design and first test results of an LTD cavity that generates such a type of output pulse by including within its circular array a number of third harmonic bricks in addition to the main bricks. A voltage adder made out of a square pulse cavity linear array will produce the same shape output pulses provided that the timing of each cavity is synchronized with the propagation of the electromagnetic pulse.

Proteome Analysis of Human Arterial Tissue Discloses Associations Between the Vascular Content of Small Leucine-Rich Repeat Proteoglycans and Pulse Wave Velocity

DEFF Research Database (Denmark)

Lyck Hansen, Maria; Beck, Hans Christian; Irmukhamedov, Akhmadjon

2015-01-01

OBJECTIVES: We hypothesized that arterial stiffness is associated with changes in the arterial protein profile, particularly of extracellular matrix components. We aimed at determining differentially expressed proteins by quantitative proteome analysis in arterial tissue from patients with differ......OBJECTIVES: We hypothesized that arterial stiffness is associated with changes in the arterial protein profile, particularly of extracellular matrix components. We aimed at determining differentially expressed proteins by quantitative proteome analysis in arterial tissue from patients...... with different degrees of arterial stiffness. APPROACH AND RESULTS: Arterial stiffness, assessed by carotid-femoral pulse wave velocity (PWV), central blood pressure and augmentation index by pulse wave analysis were measured the day before surgery in a group of patients undergoing coronary artery bypass...... grafting. Protein extracts of well-defined, homogenous, nonatherosclerotic individual samples of the left mammary artery from 10 of these patients with high PWV and 9 with low PWV were compared by quantitative proteome analysis, using tandem mass tag labeling and nano-liquid chromatography mass...

Electromagnetic pulses, localized and causal

Science.gov (United States)

Lekner, John

2018-01-01

We show that pulse solutions of the wave equation can be expressed as time Fourier superpositions of scalar monochromatic beam wave functions (solutions of the Helmholtz equation). This formulation is shown to be equivalent to Bateman's integral expression for solutions of the wave equation, for axially symmetric solutions. A closed-form one-parameter solution of the wave equation, containing no backward-propagating parts, is constructed from a beam which is the tight-focus limit of two families of beams. Application is made to transverse electric and transverse magnetic pulses, with evaluation of the energy, momentum and angular momentum for a pulse based on the general localized and causal form. Such pulses can be represented as superpositions of photons. Explicit total energy and total momentum values are given for the one-parameter closed-form pulse.

Twenty-channel high-voltage pulse generators

International Nuclear Information System (INIS)

Anan'in, P.S.; Kashirin, A.P.

1980-01-01

A 20-channel high-voltage pulse generator operating with a mismatched load is described. The generator contains shaping lines 20 m long made of coaxial cable, a trigatron-type discharged, and isolating plates. The channel characteristic impedance is 50 Ohm. The maximum pulse amplitude is up to 15 kV on a high-resistance load and 7.5 kV on a matched one. The pulse duration is 100 ns at a pulse rise time of 12 ns, the delay introduced by the generator is 200 +-2.5 ns. Provision is made in the control circuit for compensation of the shaped pulse and separation of a pulse reflected from the load. The reflected pulse shape and amplitude characterize load parameters. Generator tests proved its high operational reliability (after 10 5 operations no significant changes in generator performances have been observed). The generator is intended for filmless data output from spark chambers

The Pulse Line Ion Accelerator Concept

Energy Technology Data Exchange (ETDEWEB)

Briggs, Richard J.

2006-02-15

The Pulse Line Ion Accelerator concept was motivated by the desire for an inexpensive way to accelerate intense short pulse heavy ion beams to regimes of interest for studies of High Energy Density Physics and Warm Dense Matter. A pulse power driver applied at one end of a helical pulse line creates a traveling wave pulse that accelerates and axially confines the heavy ion beam pulse. Acceleration scenarios with constant parameter helical lines are described which result in output energies of a single stage much larger than the several hundred kilovolt peak voltages on the line, with a goal of 3-5 MeV/meter acceleration gradients. The concept might be described crudely as an ''air core'' induction linac where the PFN is integrated into the beam line so the accelerating voltage pulse can move along with the ions to get voltage multiplication.

Enhanced electrochemical response in oxidative differential pulse voltammetry of dopamine in the presence of ascorbic acid at carboxyl-terminated boron-doped diamond electrodes

Energy Technology Data Exchange (ETDEWEB)

Kondo, Takeshi [Department of Industrial Chemistry, Faculty of Engineering, Tokyo University of Science, 1-3 Kagurazaka, Shinjuku-ku, Tokyo 162-8601 (Japan)], E-mail: t.kondo@ci.kagu.tus.ac.jp; Niwano, Yu; Tamura, Akira; Imai, Junichi [Department of Industrial Chemistry, Faculty of Engineering, Tokyo University of Science, 1-3 Kagurazaka, Shinjuku-ku, Tokyo 162-8601 (Japan); Honda, Kensuke [Department of Chemistry and Earth Sciences, Faculty of Science, Yamaguchi University, 1677-1 Yoshida, Yamaguchi-shi, Yamaguchi 753-8521 (Japan); Einaga, Yasuaki [Department of Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Yokohama 223-0012 (Japan); Tryk, Donald A. [Fuel Cell Nanomaterials Center, University of Yamanashi, Takeda 4-3-11, Kofu, Yamanashi 400-8511 (Japan); Fujishima, Akira [Kanagawa Academy of Science and Technology (KAST), 3-2-1 Sakado, Takatsu-ku, Kawasaki, Kanagawa 213-0012 (Japan); Kawai, Takeshi [Department of Industrial Chemistry, Faculty of Engineering, Tokyo University of Science, 1-3 Kagurazaka, Shinjuku-ku, Tokyo 162-8601 (Japan)

2009-03-01

The differential pulse voltammetric (DPV) peak for dopamine (DA) oxidation was found to be highly amplified by the addition of ascorbic acid (AA) when carboxyl-terminated boron-doped diamond (BDD) electrodes were used as the working electrode. The DP voltammogram for a solution containing DA and AA obtained using a 4-pentenoic acid-modified BDD (4PA-BDD) electrode showed well-separated oxidation peaks for DA and AA at 0.4 and 0.6 V vs. Ag/AgCl, respectively. In addition, as the DA concentration increased at constant AA concentration, a simultaneous increase in the DA peak current density and decrease in the AA peak current density were observed. The slope of the calibration curve for the [DA] range of 1-10 {mu}M in the presence of AA (500 {mu}M) was seven times larger than that obtained in the absence of AA. Such an enhancement was found to be more efficient at 4PA-BDD than at oxidized-BDD, partly due to simple electrostatic effects and partly due to suppression of the polymerization of DA oxidation products by the terminal carboxyl groups. The enhanced detection method using a carboxyl-terminated BDD electrode should be an effective analytical tool, especially for determining low concentrations of DA in the presence of high concentrations of AA.

Enhanced electrochemical response in oxidative differential pulse voltammetry of dopamine in the presence of ascorbic acid at carboxyl-terminated boron-doped diamond electrodes

International Nuclear Information System (INIS)

Kondo, Takeshi; Niwano, Yu; Tamura, Akira; Imai, Junichi; Honda, Kensuke; Einaga, Yasuaki; Tryk, Donald A.; Fujishima, Akira; Kawai, Takeshi

2009-01-01

The differential pulse voltammetric (DPV) peak for dopamine (DA) oxidation was found to be highly amplified by the addition of ascorbic acid (AA) when carboxyl-terminated boron-doped diamond (BDD) electrodes were used as the working electrode. The DP voltammogram for a solution containing DA and AA obtained using a 4-pentenoic acid-modified BDD (4PA-BDD) electrode showed well-separated oxidation peaks for DA and AA at 0.4 and 0.6 V vs. Ag/AgCl, respectively. In addition, as the DA concentration increased at constant AA concentration, a simultaneous increase in the DA peak current density and decrease in the AA peak current density were observed. The slope of the calibration curve for the [DA] range of 1-10 μM in the presence of AA (500 μM) was seven times larger than that obtained in the absence of AA. Such an enhancement was found to be more efficient at 4PA-BDD than at oxidized-BDD, partly due to simple electrostatic effects and partly due to suppression of the polymerization of DA oxidation products by the terminal carboxyl groups. The enhanced detection method using a carboxyl-terminated BDD electrode should be an effective analytical tool, especially for determining low concentrations of DA in the presence of high concentrations of AA

Computation of the current density in nonlinear materials subjected to large current pulses

International Nuclear Information System (INIS)

Hodgdon, M.L.; Hixson, R.S.; Parsons, W.M.

1991-01-01

This paper reports that the finite element method and the finite difference method are used to calculate the current distribution in two nonlinear conductors. The first conductor is a small ferromagnetic wire subjected to a current pulse that rises to 10,000 Amperes in 10 microseconds. Results from the transient thermal and transient magnetic solvers of the finite element code FLUX2D are used to compute the current density in the wire. The second conductor is a metal oxide varistor. Maxwell's equations, Ohm's law and the varistor relation for the resistivity and the current density of p = αj -β are used to derive a nonlinear differential equation. The solutions of the differential equation are obtained by a finite difference approximation and a shooting method. The behavior predicted by these calculations is in agreement with experiments

Application of accelerator sources for pulsed neutron logging of oil and gas wells

International Nuclear Information System (INIS)

Randall, R.R.

1985-01-01

Dresser Atlas introduced the first commercial pulsed neutron oil well log in the early 1960s. This log had the capability of differentiating oil from salt water in a completed well. In the late 1970s the first continuous carbon/oxygen (C/O) log capable of differentiating oil from fresh water was introduced. The sources used in these commercial logs are radial geometry deuterium-tritium reaction devices with Cockcroft-Walton voltage multipliers providing the accelerator voltage. The commercial logging tools using these accelerators are comprised of scintillators detectors, power supplies, line drivers and receivers, and various timing and communication electronics. They are used to measure either the time decay or energy spectra of neutron-induced gamma events. The time decay information is useful in determining the neutron capture cross section, and the energy spectra is used to characterize inelastic neutron events. (orig.)

Application of accelerator sources for pulsed neutron logging of oil and gas wells

Science.gov (United States)

Randall, R. R.

1985-05-01

Dresser Atlas introduced the first commercial pulsed neutron oil well log in the early 1960s. This log had the capability of differentiating oil from salt water in a completed well. In the late 1970s the first continuous carbon/oxygen (C/O) log capable of differentiating oil from fresh water was introduced. The sources used in these commercial logs are radial geometry deuterium-tritium reaction devices with Cockcroft-Walton voltage multipliers providing the accelerator voltage. The commercial logging tools using these accelerators are comprised of scintillators detectors, power supplies, line drivers and receivers, and various timing and communications electronics. They are used to measure either the time decay or energy spectra of neutron-induced gamma events. The time decay information is useful in determining the neutron capture cross section, and the energy spectra is used to characterize inelastic neutron events.

High powered pulsed plasma enhanced deposition of thin film semiconductor and optical materials

International Nuclear Information System (INIS)

Llewellyn, I.P.; Sheach, K.J.A.; Heinecke, R.A.

1993-01-01

A glow discharge deposition technique is described which allows the deposition of a large range of high quality materials without the requirement for substrate heating. The method is differentiated from conventional plasma deposition techniques in that a much higher degree of dissociation is achieved in the gases prior to deposition, such that thermally activated surface reactions are no longer required in order to produce a dense film. The necessary discharge intensity (>300Wcm -3 ) is achieved using a high power radio frequency generator which is pulsed at a low duty cycle (1%) to keep the average energy of the discharge low (100W), in order to avoid the discharge heating the substrate. In addition, by varying the gas composition between discharge pulses, layered structures of materials can be produced, with a disordered interface about 8 A thick. Various uses of the technique in semiconductor and optical filter production are described, and the properties of films deposited using these technique are presented. (orig.)

ENDOR with band-selective shaped inversion pulses

Science.gov (United States)

Tait, Claudia E.; Stoll, Stefan

2017-04-01

Electron Nuclear DOuble Resonance (ENDOR) is based on the measurement of nuclear transition frequencies through detection of changes in the polarization of electron transitions. In Davies ENDOR, the initial polarization is generated by a selective microwave inversion pulse. The rectangular inversion pulses typically used are characterized by a relatively low selectivity, with full inversion achieved only for a limited number of spin packets with small resonance offsets. With the introduction of pulse shaping to EPR, the rectangular inversion pulses can be replaced with shaped pulses with increased selectivity. Band-selective inversion pulses are characterized by almost rectangular inversion profiles, leading to full inversion for spin packets with resonance offsets within the pulse excitation bandwidth and leaving spin packets outside the excitation bandwidth largely unaffected. Here, we explore the consequences of using different band-selective amplitude-modulated pulses designed for NMR as the inversion pulse in ENDOR. We find an increased sensitivity for small hyperfine couplings compared to rectangular pulses of the same bandwidth. In echo-detected Davies-type ENDOR, finite Fourier series inversion pulses combine the advantages of increased absolute ENDOR sensitivity of short rectangular inversion pulses and increased sensitivity for small hyperfine couplings of long rectangular inversion pulses. The use of pulses with an almost rectangular frequency-domain profile also allows for increased control of the hyperfine contrast selectivity. At X-band, acquisition of echo transients as a function of radiofrequency and appropriate selection of integration windows during data processing allows efficient separation of contributions from weakly and strongly coupled nuclei in overlapping ENDOR spectra within a single experiment.

The Toulouse pulsed magnet facility

International Nuclear Information System (INIS)

2006-01-01

The 'Laboratoire National des Champs Magnetiques Pulses' (LNCMP) is an international user facility providing access to pulsed magnetic fields up to and beyond 60 T. The laboratory disposes of 10 magnet stations equipped with long-pulse magnets operating in the 35-60 T range and a short-pulse system reaching magnetic fields in excess of 70 T. The experimental infrastructure includes various high and low-temperature systems ranging from ordinary flow-type cryostats to dilution refrigerators reaching 50 mK, as well as different types of high-pressure cells. Experimental techniques include magnetization, transport, luminescence, IR-spectroscopy and polarimetry. The LNCMP pursues an extensive in-house research program focussing on all technological and scientific aspects of pulsed magnetic fields. Recent technical developments include the implementation of 60 T rapid-cooling coils, an 80 T prototype, a pulsed dipole magnet for optical investigations of dilute matter and a transportable horizontal access magnet for small angle x-ray scattering experiments. Scientific activities cover a variety of domains, including correlated electron systems, magnetism, semiconductors and nanoscience

A 16.3 pJ/pulse low-complexity and energy-efficient transmitter with adjustable pulse parameters

International Nuclear Information System (INIS)

Jiang Jun; Zhao Yi; Shao Ke; Chen Hu; Xia Lingli; Hong Zhiliang

2011-01-01

This paper presents a novel, fully integrated transmitter for 3-5 GHz pulsed UWB. The BPSK modulation transmitter has been implemented in SMIC CMOS 0.13 μm technology with a 1.2-V supply voltage and a die size of 0.8 x 0.95 mm 2 . This transmitter is based on the impulse response filter method, which uses a tunable R paralleled with a LC frequency selection network to realize continuously adjustable pulse parameters, including bandwidth, width and amplitude. Due to the extremely low duty of the pulsed UWB, a proposed output buffer is employed to save power consumption significantly. Finally, measurement results show that the transmitter consumes only 16.3 pJ/pulse to achieve a pulse repetition rate of 100 Mb/s. Generated pulses strictly comply with the FCC spectral mask. The continuously variable pulse width is from 900 to 1.5 ns and the amplitude with the minimum 178 mVpp and the maximum 432 mVpp can be achieved. (semiconductor integrated circuits)

Herophilus on pulse

Directory of Open Access Journals (Sweden)

Afonasin, Eugene

2015-01-01

Full Text Available The first detailed study of the pulse (sphygmology is associated in antiquity with Herophilus (the end of the 4th century BCE, an Alexandrian physician, renowned for his anatomical discoveries. The scholars also attribute to him a discovery of a portable and adjustable water-clock, used for measuring ‘natural’ and ‘unnatural’ pulse and, accordingly, temperature of the patient. In the article we translate the principal ancient evidences and comment upon them. We study both the practical aspects of ancient sphygmology and the theoretical speculations associated with it. Ancient theory of proportion and musical harmony allowed to build a classification of the pulses, but the medical experience did not fit well in the Procrustean bed of this rather simple theory.

Investigation of the pulse shape analysis for the position sensitive γ-ray spectrometer AGATA

Energy Technology Data Exchange (ETDEWEB)

Lewandowski, Lars; Birkenbach, Benedikt; Reiter, Peter [Institut fuer Kernphysik Koeln (Germany); Collaboration: AGATA-Collaboration

2015-07-01

The next generation of γ-ray spectrometers like AGATA will provide high quality γ-ray spectra by the new Gamma-Ray Tracking technique (GRT). Position sensitive HPGe detectors will allow for precise Doppler correction and small broadening of lines for spectroscopy at relativistic energies. GRT is based on the interaction position of the γ-rays within the volume of the highly segmented germanium detectors provided by Pulse Shape Analysis (PSA) methods. The proof of principle of GRT was already demonstrated with great success however systematic deviations from expected results occur. The parameterization of the following detector properties and their impact on PSA were thoroughly investigated and optimized: electron and hole mobility, crystal axis orientation, space charge distributions, crystal impurities, response functions of preamplifiers and digitizers, linear and differential crosstalk, time alignment of pulses and the distance metric. Results of an improved PSA performance are presented.

Radiobiological response to ultra-short pulsed megavoltage electron beams of ultra-high pulse dose rate.

Science.gov (United States)

Beyreuther, Elke; Karsch, Leonhard; Laschinsky, Lydia; Leßmann, Elisabeth; Naumburger, Doreen; Oppelt, Melanie; Richter, Christian; Schürer, Michael; Woithe, Julia; Pawelke, Jörg

2015-08-01

In line with the long-term aim of establishing the laser-based particle acceleration for future medical application, the radiobiological consequences of the typical ultra-short pulses and ultra-high pulse dose rate can be investigated with electron delivery. The radiation source ELBE (Electron Linac for beams with high Brilliance and low Emittance) was used to mimic the quasi-continuous electron beam of a clinical linear accelerator (LINAC) for comparison with electron pulses at the ultra-high pulse dose rate of 10(10) Gy min(-1) either at the low frequency of a laser accelerator or at 13 MHz avoiding effects of prolonged dose delivery. The impact of pulse structure was analyzed by clonogenic survival assay and by the number of residual DNA double-strand breaks remaining 24 h after irradiation of two human squamous cell carcinoma lines of differing radiosensitivity. The radiation response of both cell lines was found to be independent from electron pulse structure for the two endpoints under investigation. The results reveal, that ultra-high pulse dose rates of 10(10) Gy min(-1) and the low repetition rate of laser accelerated electrons have no statistically significant influence (within the 95% confidence intervals) on the radiobiological effectiveness of megavoltage electrons.

Designs of pulsed power cryogenic transformers

International Nuclear Information System (INIS)

Singh, S.K.; Heyne, C.J.; Hackowrth, D.T.; Shestak, E.J.; Eckels, P.W.; Rogers, J.D.

1988-01-01

The Westinghouse Electric Corporation has completed designs of three pulsed power cryogenic transformers of three pulsed power cryogenic transformers for the Los Alamos National Laboratory. These transformers will be configured to transfer their stored energy sequentially to an electro-magnetic launcher and form a three-stage power supply. The pulse transformers will act as two winding energy storage solenoids which provide a high current and energy pulse compression by transforming a 50 kA power supply into a megamp level power supply more appropriate for the electromagnetic launcher duty. This system differs from more traditional transformer applications in that significant current levels do not exists simultaneously in the two windings of the pulse transformer. This paper describes the designs of the pulsed power cryogenic transformers

Single-Use Disposable Electrochemical Label-Free Immunosensor for Detection of Glycated Hemoglobin (HbA1c Using Differential Pulse Voltammetry (DPV

Directory of Open Access Journals (Sweden)

Alireza Molazemhosseini

2016-07-01

Full Text Available A single-use disposable in vitro electrochemical immunosensor for the detection of HbA1c in undiluted human serum using differential pulse voltammetry (DPV was developed. A three-electrode configuration electrochemical biosensor consisted of 10-nm-thin gold film working and counter electrodes and a thick-film printed Ag/AgCl reference electrode was fabricated on a polyethylene terephthalate (PET substrate. Micro-fabrication techniques including sputtering vapor deposition and thick-film printing were used to fabricate the biosensor. This was a roll-to-roll cost-effective manufacturing process making the single-use disposable in vitro HbA1c biosensor a reality. Self-assembled monolayers of 3-Mercaptopropionic acid (MPA were employed to covalently immobilize anti-HbA1c on the surface of gold electrodes. Electrochemical impedance spectroscopy (EIS and X-ray photoelectron spectroscopy (XPS confirmed the excellent coverage of MPA-SAM and the upward orientation of carboxylic groups. The hindering effect of HbA1c on the ferricyanide/ferrocyanide electron transfer reaction was exploited as the HbA1c detection mechanism. The biosensor showed a linear range of 7.5–20 µg/mL of HbA1c in 0.1 M PBS. Using undiluted human serum as the test medium, the biosensor presented an excellent linear behavior (R2 = 0.999 in the range of 0.1–0.25 mg/mL of HbA1c. The potential application of this biosensor for in vitro measurement of HbA1c for diabetic management was demonstrated.

Single-Use Disposable Electrochemical Label-Free Immunosensor for Detection of Glycated Hemoglobin (HbA1c) Using Differential Pulse Voltammetry (DPV).

Science.gov (United States)

Molazemhosseini, Alireza; Magagnin, Luca; Vena, Pasquale; Liu, Chung-Chiun

2016-07-01

A single-use disposable in vitro electrochemical immunosensor for the detection of HbA1c in undiluted human serum using differential pulse voltammetry (DPV) was developed. A three-electrode configuration electrochemical biosensor consisted of 10-nm-thin gold film working and counter electrodes and a thick-film printed Ag/AgCl reference electrode was fabricated on a polyethylene terephthalate (PET) substrate. Micro-fabrication techniques including sputtering vapor deposition and thick-film printing were used to fabricate the biosensor. This was a roll-to-roll cost-effective manufacturing process making the single-use disposable in vitro HbA1c biosensor a reality. Self-assembled monolayers of 3-Mercaptopropionic acid (MPA) were employed to covalently immobilize anti-HbA1c on the surface of gold electrodes. Electrochemical impedance spectroscopy (EIS) and X-ray photoelectron spectroscopy (XPS) confirmed the excellent coverage of MPA-SAM and the upward orientation of carboxylic groups. The hindering effect of HbA1c on the ferricyanide/ferrocyanide electron transfer reaction was exploited as the HbA1c detection mechanism. The biosensor showed a linear range of 7.5-20 µg/mL of HbA1c in 0.1 M PBS. Using undiluted human serum as the test medium, the biosensor presented an excellent linear behavior (R² = 0.999) in the range of 0.1-0.25 mg/mL of HbA1c. The potential application of this biosensor for in vitro measurement of HbA1c for diabetic management was demonstrated.

Sandia Pulsed Reactor Facility (SPRF) calculator-assisted pulse analysis and display system

International Nuclear Information System (INIS)

Estes, B.F.; Berry, D.T.

1980-02-01

Two solid-metal fast burst type reactors (SPR II and SPR III) are operated at the Sandia Pulsed Reactor Facility. Since startup of the reactors, oscilloscope traces have been used to record (by camera) the pulse (power) shape while log N systems have measured initial reactor period. Virtually no other pulse information is available. A decision was made to build a system that could collect the basic input data available from the reactor - fission chambers, photodiodes, and thermocouples - condition the signals and output the various parameters such as power, energy, temperature, period and lifetime on hard copy that would provide a record for operations personnel as well as the experimenter. Because the reactors operate in short time frames - pulse operation - it is convenient to utilize the classical Nordheim-Fuchs approximation of the diffusion equation to describe reactor behavior. This report describes the work performed to date in developing the calculator system and analytical models for computing the desired parameters

Pulsed high-power beams

International Nuclear Information System (INIS)

Reginato, L.L.; Birx, D.L.

1988-01-01

The marriage of induction linac technology with nonlinear magnetic modulators has produced some unique capabilities. It is now possible to produce short-pulse electron beams with average currents measured in amperes, at gradients approaching 1-MeV/m, and with power efficiencies exceeding 50%. This paper reports on a 70-MeV, 3-kA induction accelerator (ETA II) constructed at the Lawrence Livermore National Laboratory that incorporates the pulse technology concepts that have evolved over the past several years. The ETA II is a linear induction accelerator and provides a test facility for demonstration of the high-average-power components and high-brightness sources used in such accelerators. The pulse drive of the accelerator is based on state-of-the-art magnetic pulse compressors with very high peak-power capability, repetition rates exceeding 1 kHz, and excellent reliability

Pulse Compression of Phase-matched High Harmonic Pulses from a Time-Delay Compensated Monochromator

Directory of Open Access Journals (Sweden)

Ito Motohiko

2013-03-01

Full Text Available Pulse compression of single 32.6-eV high harmonic pulses from a time-delay compensated monochromator was demonstrated down to 11±3 fs by compensating the pulse front tilt. The photon flux was intensified up to 5.7×109 photons/s on target by implementing high harmonic generation under a phase matching condition in a hollow fiber used for increasing the interaction length.

A digital long pulse integrator

International Nuclear Information System (INIS)

Broesch, J.D.; Strait, E.J.; Snider, R.T.

1996-10-01

A prototype digital integrator with very long integration capabilities has been developed and field tested on an inductive magnetic sensor on the DIII-D Tokamak. The integrator is being developed for use on ITER with a pulse length of 1000 s, and has direct applications for other long pulse Tokamaks. Inductive magnetic sensors are routinely used on existing Tokamaks, are well understood, and are extremely robust, however, they require integration of the signal to determine the magnetic field strength. The next generation of Tokamaks, will have pulse lengths of 1000 s or longer, require integrators with drift and noise characteristics compatible with the very long pulse lengths. This paper will discuss the architecture, algorithms, and programming of the Long Pulse Integrator (LPI). Of particular interest are the noise control and the built-in offset correction techniques used in this application

Dynamic pulse difference circuit

International Nuclear Information System (INIS)

Erickson, G.L.

1978-01-01

A digital electronic circuit of especial use for subtracting background activity pulses in gamma spectrometry is disclosed which comprises an up-down counter connected to count up with signal-channel pulses and to count down with background-channel pulses. A detector responsive to the count position of the up-down counter provides a signal when the up-down counter has completed one scaling sequence cycle of counts in the up direction. In an alternate embodiment, a detector responsive to the count position of the up-down counter provides a signal upon overflow of the counter

Security of differential-phase-shift quantum key distribution against individual attacks

International Nuclear Information System (INIS)

Waks, Edo; Takesue, Hiroki; Yamamoto, Yoshihisa

2006-01-01

We derive a proof of security for the differential-phase-shift quantum key distribution protocol under the assumption that Eve is restricted to individual attacks. The security proof is derived by bounding the average collision probability, which leads directly to a bound on Eve's mutual information on the final key. The security proof applies to realistic sources based on pulsed coherent light. We then compare individual attacks to sequential attacks and show that individual attacks are more powerful

Attosecond pulse generation in noble gases in the presence of extreme high intensity THz pulses

International Nuclear Information System (INIS)

Balogh, E.; Varju, K.

2010-01-01

Complete text of publication follows. The shortest - attosecond - light pulses available today are produced by high harmonic generation (HHG) of near-infrared (NIR) laser pulses in noble gas jets, providing a broad spectral plateau of XUV radiation ending in a cutoff. The minimum pulse duration is determined by the achievable bandwidth (i.e. the position of the cutoff), and the chirp of the produced pulses. The extension of the cutoff by increasing the laser intensity is limited by the depletion and phase matching problems of the medium. An alternative method demonstrated to produce higher harmonic orders is by using longer pump pulse wavelength, with the disadvantage of decreased efficiency. Recently it was shown that application of a quasi-DC high strength electric field results in an increase of more than a factor of two in the order of efficiently generated high harmonics. However, the possibility to implement the method proposed in [3] of using a CO 2 laser to create a quasi-DC field for assisting HHG of the NIR laser is questionable, because it's technically very challenging to synchronize pulses from different laser sources. Alternatively, synchronous production of THz pulses with the NIR laser pulse offers a more promising route. The first numerical test of this idea has been reported in [4]. In this contribution we further investigate the method for realistic THz field strengths and short driving pulses, exploring the effect of longer pump laser wavelength on the process. We assume the presence of high intensity THz pulses for supplying the high-strength quasi-DC electric field. The spectrum as well as the chirp of the produced radiation is calculated. We use the non-adiabatic saddle point method to determine the generated radiation described in [6]. We simulate harmonic generation in noble gas atoms, with few cycle NIR pulses of peak intensity at and above 2 x 10 14 W/cm 2 (388 MV/cm) and wavelengths 800 nm and 1560 nm. The THz field strength is varied

Acousto-optic replication of ultrashort laser pulses

Science.gov (United States)

Yushkov, Konstantin B.; Molchanov, Vladimir Ya.; Ovchinnikov, Andrey V.; Chefonov, Oleg V.

2017-10-01

Precisely controlled sequences of ultrashort laser pulses are required in various scientific and engineering applications. We developed a phase-only acousto-optic pulse shaping method for replication of ultrashort laser pulses in a TW laser system. A sequence of several Fourier-transform-limited pulses is generated from a single femtosecond laser pulse by means of applying a piecewise linear phase modulation over the whole emission spectrum. Analysis demonstrates that the main factor which limits maximum delay between the pulse replicas is spectral resolution of the acousto-optic dispersive delay line used for pulse shaping. In experiments with a Cr:forsterite laser system, we obtained delays from 0.3 to 3.5 ps between two replicas of 190 fs transform-limited pulses at the central wavelength of laser emission, 1230 nm.

Coherent combining pulse bursts in time domain

Science.gov (United States)

Galvanauskas, Almantas

2018-01-09

A beam combining and pulse stacking technique is provided that enhances laser pulse energy by coherent stacking pulse bursts (i.e. non-periodic pulsed signals) in time domain. This energy enhancement is achieved by using various configurations of Fabry-Perot, Gires-Tournois and other types of resonant cavities, so that a multiple-pulse burst incident at either a single input or multiple inputs of the system produces an output with a solitary pulse, which contains the summed energy of the incident multiple pulses from all beams. This disclosure provides a substantial improvement over conventional coherent-combining methods in that it achieves very high pulse energies using a relatively small number of combined laser systems, thus providing with orders of magnitude reduction in system size, complexity, and cost compared to current combining approaches.

Determination of pseudo multi-pulse production rate in GM counters by correlation analysis between signal pulses

International Nuclear Information System (INIS)

Hashimoto, Kengo; Ueda, Taizou

1996-01-01

A technique, based on the correlation analysis of signal pulses in time sequence, is proposed to determine the production rate of the pseudo multi-pulse in Geiger-Mueller (GM) counter. With a multi-channel scaler initiated by a signal pulse, subsequent pulses are recorded in sequence. The production of the multi-pulse increases the counting probability immediately after the initiation. By examining the deviation of the measured probability from the ideal counting probability, the production rate and the average lag time to produce the multi-pulse can be determined. By the use of the present technique, the production rate and the average lag time were obtained for the various GM tubes. These results indicate that the consumption of the quench gas results in a significant increase in the production rate but little variation in the lag time, and that the lag time strongly depends on the tube diameter. (author)

Breaking time-resolution limits in pulse radiolysis

International Nuclear Information System (INIS)

Yang Jinfeng; Kondoh, Takafumi; Norizawa, Kimihiro; Yoshida, Yoichi; Tagawa, Seiichi

2009-01-01

Pulse radiolysis, which is a time-resolved stroboscopic method based on ultrashort electron pulse and ultrashort analyzing light, is widely used for the study of the chemical kinetics and radiation primary processes or reactions. Although it has become possible to use femtosecond-pulse electron beam and femtosecond laser light in pulse radiolysis, the resolution is limited by the difference in group velocities of the electrons and the light in sample. In this contribution, we introduce a concept of equivalent velocity spectroscopy (EVS) into pulse radiolysis and demonstrate the methodology experimentally. In EVS, both the electron and the analyzing light pulses precisely overlap at every point in the sample and throughout the propagation time by rotating the electron pulse. The advance allows us to overcome the resolution degradation due to the different group velocity. We also present a method for measuring the rotated angle of the electron pulse and a technique for rotating the electron pulse with a deflecting cavity.

Custom pulse generator for RPC testing

International Nuclear Information System (INIS)

Gil, A.; Castro, E.; Diaz, J.; Fonte, P.; Garzon, J.A.; Montes, N.; Zapata, M.

2009-01-01

We present a pulse generator able to generate pulses statistically similar to the ones produced by RPC cells. The device generates up to four arrays of fast and narrow random-like pulses. Polarity, maximum amplitudes, widths and pulse rate in each channel may be modified independently in order to simulate different RPC setups and environments. This portable and cost-effective pulse generator is a versatile instrument for testing FE-Electronics and different real detector features related with the signal propagation inside the detector. It has been developed in the framework of the ESTRELA project of the HADES experiment at GSI.

Temporal Airy pulses control cell poration

Directory of Open Access Journals (Sweden)

S. Courvoisier

2016-07-01

Full Text Available We show that spectral phase shaping of fs-laser pulses can be used to optimize laser-cell membrane interactions in water environment. The energy and peak intensity thresholds required for cell poration with single pulse in the nJ range can be significantly reduced (25% reduction in energy and 88% reduction in peak intensity by using temporal Airy pulses, controlled by positive third order dispersion, as compared to bandwidth limited pulses. Temporal Airy pulses are also effective to control the morphology of the induced pores, with prospective applications from cellular to tissue opto-surgery and transfection.

Infrared study of the Crab pulsar: The ''shoulder'' pulse and the 3.45 micron pulse profile

International Nuclear Information System (INIS)

Middleditch, J.; Pennypacker, C.; Burns, M.S.

1983-01-01

Infrared measurements of the Crab pulsar with the NASA IRTF 3.0 m telescope show that the spectrum of the main pulse turns downward for wavelengths longer than 3 μm. The ''shoulder'' pulse discovered by Pennypacker is measured in the 0.9--2.4 μm region, but disappears at 3.5 μm. This pulse rises from 0 to 20% of the height of the main pulse within 1 to 2 ms after the main pulse peak and decays with a 4 to 5 ms time constant. Excess infrared flux also appears after the interpulse. The main peak itself may be narrower at 3.45 μm than in the optical to 2.2 μm band

Control of giant pulse duration in neodymium mini lasers with controllable cavity length and pulsed pumping

International Nuclear Information System (INIS)

Berenberg, Vladimir A.; Cervantes, Miguel A.; Terpugov, Vladimir S.

2006-01-01

In a solid-state laser incident on aLiNdP4O12 crystal, pumped by a short light pulse, giant pulse oscillation without the use of resonator Q switching is realized. Tuning of the oscillation pulse duration from 2 up to 20 ns is achieved by changing the cavity length from 24 to 3 mm, respectively. Our analysis of this mode of laser radiation is made on the basis of the rate equations. The factors influencing oscillation pulse duration a reinvestigated. It is shown that in a limiting case the minimal value of the pulse duration is limited by only the rate of excitation transfer from the pumping band to the metastable level

Laser system using ultra-short laser pulses

Science.gov (United States)

Dantus, Marcos [Okemos, MI; Lozovoy, Vadim V [Okemos, MI; Comstock, Matthew [Milford, MI

2009-10-27

A laser system using ultrashort laser pulses is provided. In another aspect of the present invention, the system includes a laser, pulse shaper and detection device. A further aspect of the present invention employs a femtosecond laser and binary pulse shaping (BPS). Still another aspect of the present invention uses a laser beam pulse, a pulse shaper and a SHG crystal.

Column CO2 Measurement From an Airborne Solid-State Double-Pulsed 2-Micron Integrated Path Differential Absorption Lidar

Science.gov (United States)

Singh, U. N.; Yu, J.; Petros, M.; Refaat, T. F.; Remus, R.; Fay, J.; Reithmaier, K.

2014-01-01

NASA LaRC is developing and integrating a double-Pulsed 2-micron direct detection IPDA lidar for CO2 column measurement from an airborne platform. The presentation will describe the development of the 2-micrometers IPDA lidar system and present the airborne measurement of column CO2 and will compare to in-situ measurement for various ground target of different reflectivity.

Picoseconds pulse generation and pulse width determination processes of a distributed feedback dye laser

International Nuclear Information System (INIS)

Abdul Ghani, B.; Hammadi, M.

2004-08-01

A mathematical model has been developed to describe the dynamic emission of Nd-glass, distributed feedback dye laser (DFDL), and periodical grating temperature. The suggested model allows the investigation of the time behavior of Nd-glass laser and DFDL pulsed. Moreover, it allows studying the effect of the laser input parameters of Nd-glass laser on the spectral characteristics of the output DFDL pulses such as pulse width, delay time, and time separation

A Novel Transcranial Magnetic Stimulator Inducing Near Rectangular Pulses with Controllable Pulse Width (cTMS)

Science.gov (United States)

Jalinous, Reza; Lisanby, Sarah H.

2013-01-01

A novel transcranial magnetic stimulation (TMS) device with controllable pulse width (PW) and near rectangular pulse shape (cTMS) is described. The cTMS device uses an insulated gate bipolar transistor (IGBT) with appropriate snubbers to switch coil currents up to 7 kA, enabling PW control from 5 μs to over 100 μs. The near-rectangular induced electric field pulses use 22–34% less energy and generate 67–72% less coil heating compared to matched conventional cosine pulses. CTMS is used to stimulate rhesus monkey motor cortex in vivo with PWs of 20 to 100 μs, demonstrating the expected decrease of threshold pulse amplitude with increasing PW. The technological solutions used in the cTMS prototype can expand functionality, and reduce power consumption and coil heating in TMS, enhancing its research and therapeutic applications. PMID:18232369