WorldWideScience

Sample records for detection and identification devices

  1. 21 CFR 872.1740 - Caries detection device.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Caries detection device. 872.1740 Section 872.1740...) MEDICAL DEVICES DENTAL DEVICES Diagnostic Devices § 872.1740 Caries detection device. (a) Identification. The caries detection device is a device intended to show the existence of decay in a patient's tooth...

  2. 21 CFR 872.1745 - Laser fluorescence caries detection device.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Laser fluorescence caries detection device. 872... SERVICES (CONTINUED) MEDICAL DEVICES DENTAL DEVICES Diagnostic Devices § 872.1745 Laser fluorescence caries detection device. (a) Identification. A laser fluorescence caries detection device is a laser, a...

  3. Device-Free Passive Identity Identification via WiFi Signals.

    Science.gov (United States)

    Lv, Jiguang; Yang, Wu; Man, Dapeng

    2017-11-02

    Device-free passive identity identification attracts much attention in recent years, and it is a representative application in sensorless sensing. It can be used in many applications such as intrusion detection and smart building. Previous studies show the sensing potential of WiFi signals in a device-free passive manner. It is confirmed that human's gait is unique from each other similar to fingerprint and iris. However, the identification accuracy of existing approaches is not satisfactory in practice. In this paper, we present Wii, a device-free WiFi-based Identity Identification approach utilizing human's gait based on Channel State Information (CSI) of WiFi signals. Principle Component Analysis (PCA) and low pass filter are applied to remove the noises in the signals. We then extract several entities' gait features from both time and frequency domain, and select the most effective features according to information gain. Based on these features, Wii realizes stranger recognition through Gaussian Mixture Model (GMM) and identity identification through a Support Vector Machine (SVM) with Radial Basis Function (RBF) kernel. It is implemented using commercial WiFi devices and evaluated on a dataset with more than 1500 gait instances collected from eight subjects walking in a room. The results indicate that Wii can effectively recognize strangers and can achieves high identification accuracy with low computational cost. As a result, Wii has the potential to work in typical home security systems.

  4. Device-Free Passive Identity Identification via WiFi Signals

    Directory of Open Access Journals (Sweden)

    Jiguang Lv

    2017-11-01

    Full Text Available Device-free passive identity identification attracts much attention in recent years, and it is a representative application in sensorless sensing. It can be used in many applications such as intrusion detection and smart building. Previous studies show the sensing potential of WiFi signals in a device-free passive manner. It is confirmed that human’s gait is unique from each other similar to fingerprint and iris. However, the identification accuracy of existing approaches is not satisfactory in practice. In this paper, we present Wii, a device-free WiFi-based Identity Identification approach utilizing human’s gait based on Channel State Information (CSI of WiFi signals. Principle Component Analysis (PCA and low pass filter are applied to remove the noises in the signals. We then extract several entities’ gait features from both time and frequency domain, and select the most effective features according to information gain. Based on these features, Wii realizes stranger recognition through Gaussian Mixture Model (GMM and identity identification through a Support Vector Machine (SVM with Radial Basis Function (RBF kernel. It is implemented using commercial WiFi devices and evaluated on a dataset with more than 1500 gait instances collected from eight subjects walking in a room. The results indicate that Wii can effectively recognize strangers and can achieves high identification accuracy with low computational cost. As a result, Wii has the potential to work in typical home security systems.

  5. Fuel number identification method and device therefor

    International Nuclear Information System (INIS)

    Doi, Takami; Seno, Makoto; Tanaka, Keiji

    1998-01-01

    The present invention provides a method of and a device for automatically identifying the number on the upper surface of a fuel of a fuel assembly in a PWR type reactor. Namely, the number on the upper surface of the fuel assembly of the PWR is not arranged in a row, but indent letters are dispersed to predetermined positions of the surface to be indented. Accordingly, the identification of letters is difficult. In the present invention, the letters are identified by the following procedures. Procedure (1): the letters are detected while having a corner portion of the upper surface of a fuel assembly where the number is indented as characteristic points. A procedure (2): a letter region is determined to a relative position based on the characteristic points while determining indent letters having the same direction as one group. A procedure (3): a letter identification treatment is applied to the letter images in the above-mentioned letter region to identify them. A neural network is used for the letter identification treatment. (N.H.)

  6. MODAL TRACKING of A Structural Device: A Subspace Identification Approach

    Energy Technology Data Exchange (ETDEWEB)

    Candy, J. V. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Franco, S. N. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Ruggiero, E. L. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Emmons, M. C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Lopez, I. M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Stoops, L. M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2017-03-20

    Mechanical devices operating in an environment contaminated by noise, uncertainties, and extraneous disturbances lead to low signal-to-noise-ratios creating an extremely challenging processing problem. To detect/classify a device subsystem from noisy data, it is necessary to identify unique signatures or particular features. An obvious feature would be resonant (modal) frequencies emitted during its normal operation. In this report, we discuss a model-based approach to incorporate these physical features into a dynamic structure that can be used for such an identification. The approach we take after pre-processing the raw vibration data and removing any extraneous disturbances is to obtain a representation of the structurally unknown device along with its subsystems that capture these salient features. One approach is to recognize that unique modal frequencies (sinusoidal lines) appear in the estimated power spectrum that are solely characteristic of the device under investigation. Therefore, the objective of this effort is based on constructing a black box model of the device that captures these physical features that can be exploited to “diagnose” whether or not the particular device subsystem (track/detect/classify) is operating normally from noisy vibrational data. Here we discuss the application of a modern system identification approach based on stochastic subspace realization techniques capable of both (1) identifying the underlying black-box structure thereby enabling the extraction of structural modes that can be used for analysis and modal tracking as well as (2) indicators of condition and possible changes from normal operation.

  7. Leak detecting and identifying device in a reactor container

    International Nuclear Information System (INIS)

    Ito, Toshiichiro; Tomisawa, Teruaki; Yamada, Minoru.

    1987-01-01

    Purpose: To facilitate early detection and position identification for the leakages in a reactor container, shorten the start-up time for the nuclear power plant and reduce the equipment damages due to leakage. Constitution: Sensor signals from image sensors for obtaining infrared radiation image data are converted into image information and sent to a diagnosis device. While on the other hand, process variant signals from a process computer for obtaining plant status data are sent to a status judging device by which the plant status is judged based on the process variants such as water level, pressure and radioactivity in the reactor. The status judging device retrieves the status image aligned with the present plant status sent from the first memory device and transfers reference image information signals to the diagnosis device as the reference. The diagnosis device compares the present images with the reference images and displays the result of the judgement on CRT. (Yoshino, Y.)

  8. Load power device and system for real-time execution of hierarchical load identification algorithms

    Science.gov (United States)

    Yang, Yi; Madane, Mayura Arun; Zambare, Prachi Suresh

    2017-11-14

    A load power device includes a power input; at least one power output for at least one load; and a plurality of sensors structured to sense voltage and current at the at least one power output. A processor is structured to provide real-time execution of: (a) a plurality of load identification algorithms, and (b) event detection and operating mode detection for the at least one load.

  9. Coolant leakage detecting device

    International Nuclear Information System (INIS)

    Yamauchi, Kiyoshi; Kawai, Katsunori; Ishihara, Yoshinao.

    1995-01-01

    The device of the present invention judges an amount of leakage of primary coolants of a PWR power plant at high speed. Namely, a mass of coolants contained in a pressurizer, a volume controlling tank and loop regions is obtained based on a preset relational formula and signals of each of process amount, summed up to determine the total mass of coolants for every period of time. The amount of leakage for every period of time is calculated by a formula of Karman's filter based on the total mass of the primary coolants for every predetermined period of time, and displays it on CRT. The Karman's filter is formed on every formula for several kinds of states formed based on the preset amount of the leakage, to calculate forecasting values for every mass of coolants. An adaptable probability for every preset leakage amount is determined based on the difference between the forecast value and the observed value and the scattering thereof. The adaptable probability is compared with a predetermined threshold value, which is displayed on the CRT. This device enables earlier detection of leakage and identification of minute leakage amount as compared with the prior device. (I.S.)

  10. Flaw detection device

    International Nuclear Information System (INIS)

    Sasahara, Toshihiko

    1998-01-01

    The present invention provides a device for detecting welded portions of a reactor pressure vessel. Namely, the device of the present invention comprises (1) a casing to be disposed on the surface to be detected, (2) a probe driving means loaded to the casing, (3) a probe driven along the surface to be detected and (4) a pressure reduction means for keeping the hollow portion in the casing to an evacuated atmosphere. The casing comprises a flexible suction edge to be tightly in contact with the surface to be tested for maintaining the air tight state, (6) a guide wheel for moving the casing along the surface to be tested and (7) a handle for performing transferring operation. The flaw detection device thus constituted has following features. The working efficiency upon conducting detection is improved. The influence of the weight of the device on the detection is small. The device can be applied on the surface of a nonmagnetic material. The efficiency for the flaw detection can be improved. (I.S.)

  11. Fuel number identification method and device

    International Nuclear Information System (INIS)

    Doi, Takami; Seno, Makoto; Kikuchi, Takashi; Sakamoto, Hiromi; Takahashi, Masaki; Tanaka, Keiji.

    1997-01-01

    The present invention provides a method of and a device for automatically identifying fuel numbers impressed on fuel assemblies disposed in a fuel reprocessing facility, power plant and a reactor core at a high speed and at a high identification rate. Namely, three or more character images are photographed for one fuel assembly as an object of the identification under different illumination conditions. As a result, different character images by the number of the illumination directions can be obtained for identical impressed characters. Learning on a neural network system is applied to the images of all of the characters impressed on the fuel assembly obtained under illumination of predetermined directions. Then, result of the identification by the number of the illumination directions can be obtained for each of the characters as an object of the identification. As a result, since the result of the identification is determined based on a theory of decision of majority, highly automatic identification can be realized. (I.S.)

  12. Remote detection device and detection method therefor

    International Nuclear Information System (INIS)

    Kogure, Sumio; Yoshida, Yoji; Matsuo, Takashiro; Takehara, Hidetoshi; Kojima, Shinsaku.

    1997-01-01

    The present invention provides a non-destructive detection device for collectively, efficiently and effectively conducting maintenance and detection for confirming the integrity of a nuclear reactor by way of a shielding member for shielding radiation rays generated from an objective portion to be detected. Namely, devices for direct visual detection using an under water TV camera as a sensor, an eddy current detection using a coil as a sensor and each magnetic powder flow detection are integrated and applied collectively. Specifically, the visual detection by using the TV camera and the eddy current flaw detection are adopted together. The flaw detection with magnetic powder is applied as a means for confirming the results of the two kinds of detections by other method. With such procedures, detection techniques using respective specific theories are combined thereby enabling to enhance the accuracy for the evaluation of the detection. (I.S.)

  13. Identification performance of homeland security pocket and fixed devices for masking scenarios

    International Nuclear Information System (INIS)

    Schulcz, Francis; Gunnink, Ray; Giribaldi, Vincent; Ellenboegen, Michal

    2008-01-01

    Full text: The paper presents the principle and results of recent tests of the spectrometric pocket radiation detector PDS100GN/ID and of the spectrometric portal SPIR-Ident. We have first considered the masking scenarios listed in the relevant standards of illicit trafficking. Then we considered a larger choice of realistic masking scenarios in particular, popular medical isotopes mixed with special nuclear material. We estimated through direct measurements or by simulation based on recorded or synthesized spectra the limit of imbalance that can be detected. The consequences about the use and settings of the detection and identification devices are discussed. (author)

  14. Calibration experiments of neutron source identification and detection in soil

    International Nuclear Information System (INIS)

    Gorin, N. V.; Lipilina, E. N.; Rukavishnikov, G. V.; Shmakov, D. V.; Ulyanov, A. I.

    2007-01-01

    In the course of detection of fissile materials in soil, series of calibration experiments were carried out on in laboratory conditions on an experimental installation, presenting a mock-up of an endless soil with various heterogeneous bodies in it, fissile material, measuring boreholes. A design of detecting device, methods of neutrons detection are described. Conditions of neutron background measuring are given. Soil density, humidity, chemical composition of soil was measured. Sensitivity of methods of fissile materials detection and identification in soil was estimated in the calibration experiments. Minimal detectable activity and the distance at which it can be detected were defined. Characteristics of neutron radiation in a borehole mock-up were measured; dependences of method sensitivities from water content in soil, source-detector distance and presence of heterogeneous bodies were examined. Possibility of direction detection to a fissile material as neutron source from a borehole using a collimator is shown. Identification of fissile material was carried out by measuring the gamma-spectrum. Mathematical modeling was carried out using the PRIZMA code (Developed in RFNC-VNIITF) and MCNP code (Developed in LANL). Good correlation of calculational and experimental values was shown. The methodic were shown to be applicable in the field conditions

  15. Detection system for the identification of heavy ions

    International Nuclear Information System (INIS)

    Abriola, Daniel H.; Arazi, Andres; Achterberg, Erhard; Capurro, Oscar A.; Fernandez Niello, Jorge O.; Ferrero, Armando M. J.; Liberman, Rosa G.; Marti, Guillermo V.; Pacheco, Alberto J.; Ramirez, Marcelo C.; Testoni, Jorge E.

    1999-01-01

    The TANDAR laboratory has a magnetic spectrometer as one of its detection facilities. This device allows the separation of incident particles according to the relation between their lineal momentum and their charge state. To complete this identification there are two alternatives: 1) A system of three detectors consisting of a multiwire detector, an ionization chamber and scintillators; 2) A segmented anode ionization chamber. (author)

  16. Communications device identification methods, communications methods, wireless communications readers, wireless communications systems, and articles of manufacture

    Science.gov (United States)

    Steele, Kerry D [Kennewick, WA; Anderson, Gordon A [Benton City, WA; Gilbert, Ronald W [Morgan Hill, CA

    2011-02-01

    Communications device identification methods, communications methods, wireless communications readers, wireless communications systems, and articles of manufacture are described. In one aspect, a communications device identification method includes providing identification information regarding a group of wireless identification devices within a wireless communications range of a reader, using the provided identification information, selecting one of a plurality of different search procedures for identifying unidentified ones of the wireless identification devices within the wireless communications range, and identifying at least some of the unidentified ones of the wireless identification devices using the selected one of the search procedures.

  17. Edge detection of iris of the eye for human biometric identification system

    Directory of Open Access Journals (Sweden)

    Kateryna O. Tryfonova

    2015-03-01

    Full Text Available Method of human biometric identification by iris of the eye is considered as one of the most accurate and reliable methods of identification. Aim of the research is to solve the problem of edge detection of digital image of the human eye iris to be able to implement human biometric identification system by means of mobile device. To achieve this aim the algorithm of edge detection by Canny is considered in work. It consists of the following steps: smoothing, finding gradients, non-maximum suppression, double thresholding with hysteresis. The software implementation of the Canny algorithm is carried out for the Android mobile platform with the use of high level programming language Java.

  18. A new wireless detection device for the in-situ identification of Salmonella Typhimurium

    Science.gov (United States)

    Chai, Yating; Wikle, Howard C.; Park, Mi-kyung; Horikawa, Shin; Hong, Xie; Chin, Bryan A.

    2013-05-01

    This paper presents a new device and method for the in-situ detection of Salmonella Typhimurium on tomato surfaces. This real-time in-situ detection was accomplished with phage-based magnetoelastic (ME) biosensors on fresh food surfaces. The E2 phage from a landscape phage library serves as the bio-recognition element that has the capability of binding specifically with S. Typhimurium. This mass-sensitive ME biosensor is wirelessly actuated into mechanical resonance by an externally applied time-varying magnetic field. When the biosensor binds with S. Typhimurium, the mass of the sensor increases, resulting in a decrease in the sensor's resonant frequency. Until now, ME sensors had to be collected from the tomato surface where they are exposed to S. Typhimurium and inserted into a measurement coil for the detection of the bacterium. In contrast, the newly designed test device allows the whole detection process to take place directly on the tomato. Changes in resonant frequency over time due to the accumulation of S. Typhimurium on the sensor were measured and are presented. Real-time in-situ detection of 20 minutes was achieved. In addition, this new methodology effectively decreases the measurement error and enables the simultaneous detection of multiple pathogens.

  19. Anti-theft device staining on banknotes detected by mass spectrometry imaging.

    Science.gov (United States)

    Correa, Deleon Nascimento; Zacca, Jorge Jardim; Rocha, Werickson Fortunato de Carvalho; Borges, Rodrigo; de Souza, Wanderley; Augusti, Rodinei; Eberlin, Marcos Nogueira; Vendramini, Pedro Henrique

    2016-03-01

    We describe the identification and limits of detection of ink staining by mass spectrometry imaging (MSI), as used in anti-theft devices (ATDs). Such ink staining is applied to banknotes during automated teller machine (ATM) explosions. Desorption electrospray ionization (DESI) coupled with high-resolution and high-accuracy orbitrap mass spectrometry (MS) and a moving stage device were applied to obtain 2D molecular images of the major dyes used for staining, that is, 1-methylaminoanthraquinone (MAAQ), rhodamine B (RB) and rhodamine 6G (R6G). MAAQ could not be detected because of its inefficient desorption by DESI from the banknote cellulose surface. By contrast, ATD staining on banknotes is perceptible by the human naked eye only at concentrations higher than 0.2 μg cm(-2), whereas both RB and R6G at concentrations 200 times lower (as low as 0.001 μg cm(-2)) could be easily detected and imaged by DESI-MSI, with selective and specific identification of each analyte and their spatial distribution on samples from suspects. This technique is non-destructive, and no sample preparation is required, which ensures sample preservation for further forensic investigations. Copyright © 2016. Published by Elsevier Ireland Ltd.

  20. Facial expression identification using 3D geometric features from Microsoft Kinect device

    Science.gov (United States)

    Han, Dongxu; Al Jawad, Naseer; Du, Hongbo

    2016-05-01

    Facial expression identification is an important part of face recognition and closely related to emotion detection from face images. Various solutions have been proposed in the past using different types of cameras and features. Microsoft Kinect device has been widely used for multimedia interactions. More recently, the device has been increasingly deployed for supporting scientific investigations. This paper explores the effectiveness of using the device in identifying emotional facial expressions such as surprise, smile, sad, etc. and evaluates the usefulness of 3D data points on a face mesh structure obtained from the Kinect device. We present a distance-based geometric feature component that is derived from the distances between points on the face mesh and selected reference points in a single frame. The feature components extracted across a sequence of frames starting and ending by neutral emotion represent a whole expression. The feature vector eliminates the need for complex face orientation correction, simplifying the feature extraction process and making it more efficient. We applied the kNN classifier that exploits a feature component based similarity measure following the principle of dynamic time warping to determine the closest neighbors. Preliminary tests on a small scale database of different facial expressions show promises of the newly developed features and the usefulness of the Kinect device in facial expression identification.

  1. Identification of Bodies by Unique Serial Numbers on Implanted Medical Devices.

    Science.gov (United States)

    Blessing, Melissa M; Lin, Peter T

    2018-05-01

    Visual identification is the most common identification method used by medical examiners but is not always possible. Alternative methods include X-ray, fingerprint, or DNA comparison, but these methods require additional resources. Comparison of serial numbers on implanted medical devices is a rapid and definitive method of identification. To assess the practicality of using this method, we reviewed 608 consecutive forensic autopsies performed at a regional medical examiner office. Of these, 56 cases required an alternative method of identification due to decomposition (n = 35), gunshot wound (n = 9), blunt trauma (n = 6), or charring (n = 6). Of these 56 cases, eight (14.3%) were known to have an implanted medical device. Of these eight cases, five (63%) could be positively identified by comparing serial numbers. If an implanted medical device is known to be present, and medical records are available, identification by medical device serial number should be a first-line method. © 2017 American Academy of Forensic Sciences.

  2. Remote detection of electronic devices

    Science.gov (United States)

    Judd, Stephen L [Los Alamos, NM; Fortgang, Clifford M [Los Alamos, NM; Guenther, David C [Los Alamos, NM

    2012-09-25

    An apparatus and method for detecting solid-state electronic devices are described. Non-linear junction detection techniques are combined with spread-spectrum encoding and cross correlation to increase the range and sensitivity of the non-linear junction detection and to permit the determination of the distances of the detected electronics. Nonlinear elements are detected by transmitting a signal at a chosen frequency and detecting higher harmonic signals that are returned from responding devices.

  3. Failed fuel detection device

    International Nuclear Information System (INIS)

    Doi, Akira.

    1994-01-01

    The device of the present invention concerns a failed fuel detection device for a nuclear reactor, such as an FBR type reactor, using electroconductive coolants. A sampling port is disposed at the upper portion of the fuel assembly so as to cover the assembly, so that coolants in the fuel assembly are sampled to improve a device for detecting fuel failure. That is, when coolants in the fuel assembly are sampled from the sampling port, the flow of electroconductive coolants in an sampling tube is detected by a flowmeter, to control an electromagnetic pump. The flow of electroconductive coolants is stopped against the waterhead pressure and dynamic pressure of the conductive coolants, and a predetermined amount of the coolants is pumped up to the sampling tank. Gas is supplied to the pumped up coolants so that fissile products are transferred from the coolants to a gas phase. Radiation in the gas in a gas recycling system is measured to detect presence of fuel failure. (I.S.)

  4. Detection of chaotic dynamics in human gait signals from mobile devices

    Science.gov (United States)

    DelMarco, Stephen; Deng, Yunbin

    2017-05-01

    The ubiquity of mobile devices offers the opportunity to exploit device-generated signal data for biometric identification, health monitoring, and activity recognition. In particular, mobile devices contain an Inertial Measurement Unit (IMU) that produces acceleration and rotational rate information from the IMU accelerometers and gyros. These signals reflect motion properties of the human carrier. It is well-known that the complexity of bio-dynamical systems gives rise to chaotic dynamics. Knowledge of chaotic properties of these systems has shown utility, for example, in detecting abnormal medical conditions and neurological disorders. Chaotic dynamics has been found, in the lab, in bio-dynamical systems data such as electrocardiogram (heart), electroencephalogram (brain), and gait data. In this paper, we investigate the following question: can we detect chaotic dynamics in human gait as measured by IMU acceleration and gyro data from mobile phones? To detect chaotic dynamics, we perform recurrence analysis on real gyro and accelerometer signal data obtained from mobile devices. We apply the delay coordinate embedding approach from Takens' theorem to reconstruct the phase space trajectory of the multi-dimensional gait dynamical system. We use mutual information properties of the signal to estimate the appropriate delay value, and the false nearest neighbor approach to determine the phase space embedding dimension. We use a correlation dimension-based approach together with estimation of the largest Lyapunov exponent to make the chaotic dynamics detection decision. We investigate the ability to detect chaotic dynamics for the different one-dimensional IMU signals, across human subject and walking modes, and as a function of different phone locations on the human carrier.

  5. Biometric identification devices -- Laboratory testing vs. real life

    International Nuclear Information System (INIS)

    Ahrens, J.S.

    1997-01-01

    For over fifteen years Sandia National Laboratories has been involved in laboratory testing of biometric identification devices. The key concept of biometric identification devices is the ability for the system to identify some unique aspect of the individual rather than some object a person may be carrying or some password they are required to know. Tests were conducted to verify manufacturer's performance claims, to determine strengths/weaknesses of devices, and to determine devices that meet the US Department of energy's needs. However, during recent field installation, significantly different performance was observed than was predicted by laboratory tests. Although most people using the device believed it operated adequately, the performance observed was over an order of magnitude worse than predicted. The search for reasons behind this gap between the predicted and the actual performance has revealed many possible contributing factors. As engineers, the most valuable lesson to be learned from this experience is the value of scientists and engineers with (1) common sense, (2) knowledge of human behavior, (3) the ability to observe the real world, and (4) the capability to realize the significant differences between controlled experiments and actual installations

  6. Spatial-Temporal Synchrophasor Data Characterization and Analytics in Smart Grid Fault Detection, Identification, and Impact Causal Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Jiang, Huaiguang; Dai, Xiaoxiao; Gao, David Wenzhong; Zhang, Jun Jason; Zhang, Yingchen; Muljadi, Eduard

    2016-09-01

    An approach of big data characterization for smart grids (SGs) and its applications in fault detection, identification, and causal impact analysis is proposed in this paper, which aims to provide substantial data volume reduction while keeping comprehensive information from synchrophasor measurements in spatial and temporal domains. Especially, based on secondary voltage control (SVC) and local SG observation algorithm, a two-layer dynamic optimal synchrophasor measurement devices selection algorithm (OSMDSA) is proposed to determine SVC zones, their corresponding pilot buses, and the optimal synchrophasor measurement devices. Combining the two-layer dynamic OSMDSA and matching pursuit decomposition, the synchrophasor data is completely characterized in the spatial-temporal domain. To demonstrate the effectiveness of the proposed characterization approach, SG situational awareness is investigated based on hidden Markov model based fault detection and identification using the spatial-temporal characteristics generated from the reduced data. To identify the major impact buses, the weighted Granger causality for SGs is proposed to investigate the causal relationship of buses during system disturbance. The IEEE 39-bus system and IEEE 118-bus system are employed to validate and evaluate the proposed approach.

  7. Detection device

    Science.gov (United States)

    Smith, J.E.

    1981-02-27

    The present invention is directed to a detection device comprising: (1) an entrance chamber; (2) a central chamber; and (3) an exit chamber. The central chamber includes an ionizing gas, anode, and means for connecting the anode with an external power supply and pulse counter.

  8. An ontology-based annotation of cardiac implantable electronic devices to detect therapy changes in a national registry.

    Science.gov (United States)

    Rosier, Arnaud; Mabo, Philippe; Chauvin, Michel; Burgun, Anita

    2015-05-01

    The patient population benefitting from cardiac implantable electronic devices (CIEDs) is increasing. This study introduces a device annotation method that supports the consistent description of the functional attributes of cardiac devices and evaluates how this method can detect device changes from a CIED registry. We designed the Cardiac Device Ontology, an ontology of CIEDs and device functions. We annotated 146 cardiac devices with this ontology and used it to detect therapy changes with respect to atrioventricular pacing, cardiac resynchronization therapy, and defibrillation capability in a French national registry of patients with implants (STIDEFIX). We then analyzed a set of 6905 device replacements from the STIDEFIX registry. Ontology-based identification of therapy changes (upgraded, downgraded, or similar) was accurate (6905 cases) and performed better than straightforward analysis of the registry codes (F-measure 1.00 versus 0.75 to 0.97). This study demonstrates the feasibility and effectiveness of ontology-based functional annotation of devices in the cardiac domain. Such annotation allowed a better description and in-depth analysis of STIDEFIX. This method was useful for the automatic detection of therapy changes and may be reused for analyzing data from other device registries.

  9. Leakage detection device for weld portion

    International Nuclear Information System (INIS)

    Shinkawa, Toshio; Setokuchi, Sadayuki.

    1994-01-01

    The present invention concerns leakage detection device for weld portions, for example, in a nuclear reactor cavity, which can rapidly detect by remote control. That is, a detection device capable of self running and stopping on a guide rail along a weld line is disposed. The detection device comprises a coating mechanism for automatically coating soap water to the weld portion, a vacuum box capable of evacuating the coated surface and a camera for detecting the presence or absence of the soap bubbles generated under the evacuation. Such a device can conduct, by remote control, self running/stopping along with the weld line, coating of the soap water, settling of the vacuum box and confirmation and recording of foaming by using a television monitor. Accordingly, leakage in the weld portion in the reactor cavity or the like can be inspected. As a result, it greatly contributes to improvement of danger upon worker's operation at high place, detection accuracy and reliability of detection and shortening of operation period. (I.S.)

  10. A portable air jet actuator device for mechanical system identification

    Science.gov (United States)

    Belden, Jesse; Staats, Wayne L.; Mazumdar, Anirban; Hunter, Ian W.

    2011-03-01

    System identification of limb mechanics can help diagnose ailments and can aid in the optimization of robotic limb control parameters and designs. An interesting fluid phenomenon—the Coandă effect—is utilized in a portable actuator to provide a stochastic binary force disturbance to a limb system. The design of the actuator is approached with the goal of creating a portable device which could be deployed on human or robotic limbs for in situ mechanical system identification. The viability of the device is demonstrated by identifying the parameters of an underdamped elastic beam system with fixed inertia and stiffness and variable damping. The nonparametric compliance impulse response yielded from the system identification is modeled as a second-order system and the resultant parameters are found to be in excellent agreement with those found using more traditional system identification techniques. The current design could be further miniaturized and developed as a portable, wireless, unrestrained mechanical system identification instrument for less intrusive and more widespread use.

  11. Fundamental problems in fault detection and identification

    DEFF Research Database (Denmark)

    Saberi, Ali; Stoorvogel, Anton A.; Sannuti, Peddapullaiah

    1999-01-01

    For certain fundamental problems in fault detection and identification, the necessary and sufficient conditions for their solvability are derived. These conditions are weaker than the ones found in the literature, since we do not assume any particular structure for the residual generator......For certain fundamental problems in fault detection and identification, the necessary and sufficient conditions for their solvability are derived. These conditions are weaker than the ones found in the literature, since we do not assume any particular structure for the residual generator...

  12. Medicine Delivery Device with Integrated Sterilization and Detection

    Science.gov (United States)

    Shearn, Michael J.; Greer, Harold F.; Manohara, Harish

    2013-01-01

    or identification of the medicine itself. This constrained volume that is located immediately prior to delivery into a patient, ensures that the medicine delivery device is inherently sterile. An additional benefit to integrating a high-surface-area template within the fluid channel of a medicine delivery device is that one can envision a number of different functional coatings that could facilitate the capture and analysis of either microbial contaminants or the medicine itself. For example, one could attach antibodies or some other binding agent with a specific affinity to the silicon nanotip template. Once a target molecule or microbe is bound to the high-surface- area template, one could use an optical analytical technique such as fluorescence or adsorption to determine the identity and potentially the concentration of the species of interest. By illuminating the bound species from the back, it may also be possible to probe only the molecules with an evanescent wave, making detection of the species from the front side of the device much simpler.

  13. Camouflage, detection and identification of moving targets.

    Science.gov (United States)

    Hall, Joanna R; Cuthill, Innes C; Baddeley, Roland; Shohet, Adam J; Scott-Samuel, Nicholas E

    2013-05-07

    Nearly all research on camouflage has investigated its effectiveness for concealing stationary objects. However, animals have to move, and patterns that only work when the subject is static will heavily constrain behaviour. We investigated the effects of different camouflages on the three stages of predation-detection, identification and capture-in a computer-based task with humans. An initial experiment tested seven camouflage strategies on static stimuli. In line with previous literature, background-matching and disruptive patterns were found to be most successful. Experiment 2 showed that if stimuli move, an isolated moving object on a stationary background cannot avoid detection or capture regardless of the type of camouflage. Experiment 3 used an identification task and showed that while camouflage is unable to slow detection or capture, camouflaged targets are harder to identify than uncamouflaged targets when similar background objects are present. The specific details of the camouflage patterns have little impact on this effect. If one has to move, camouflage cannot impede detection; but if one is surrounded by similar targets (e.g. other animals in a herd, or moving background distractors), then camouflage can slow identification. Despite previous assumptions, motion does not entirely 'break' camouflage.

  14. Microarrays for Universal Detection and Identification of Phytoplasmas

    DEFF Research Database (Denmark)

    Nicolaisen, Mogens; Nyskjold, Henriette; Bertaccini, Assunta

    2013-01-01

    Detection and identification of phytoplasmas is a laborious process often involving nested PCR followed by restriction enzyme analysis and fine-resolution gel electrophoresis. To improve throughput, other methods are needed. Microarray technology offers a generic assay that can potentially detect...... and differentiate all types of phytoplasmas in one assay. The present protocol describes a microarray-based method for identification of phytoplasmas to 16Sr group level....

  15. A portable neutron spectroscope (NSPECT) for detection, imaging and identification of nuclear material

    Science.gov (United States)

    Ryan, James M.; Bancroft, Christopher; Bloser, Peter; Bravar, Ulisse; Fourguette, Dominique; Frost, Colin; Larocque, Liane; McConnell, Mark L.; Legere, Jason; Pavlich, Jane; Ritter, Greg; Wassick, Greg; Wood, Joshua; Woolf, Richard

    2010-08-01

    We have developed, fabricated and tested a prototype imaging neutron spectrometer designed for real-time neutron source location and identification. Real-time detection and identification is important for locating materials. These materials, specifically uranium and transuranics, emit neutrons via spontaneous or induced fission. Unlike other forms of radiation (e.g. gamma rays), penetrating neutron emission is very uncommon. The instrument detects these neutrons, constructs images of the emission pattern, and reports the neutron spectrum. The device will be useful for security and proliferation deterrence, as well as for nuclear waste characterization and monitoring. The instrument is optimized for imaging and spectroscopy in the 1-20 MeV range. The detection principle is based upon multiple elastic neutron-proton scatters in organic scintillator. Two detector panel layers are utilized. By measuring the recoil proton and scattered neutron locations and energies, the direction and energy spectrum of the incident neutrons can be determined and discrete and extended sources identified. Event reconstruction yields an image of the source and its location. The hardware is low power, low mass, and rugged. Its modular design allows the user to combine multiple units for increased sensitivity. We will report the results of laboratory testing of the instrument, including exposure to a calibrated Cf-252 source. Instrument parameters include energy and angular resolution, gamma rejection, minimum source identification distances and times, and projected effective area for a fully populated instrument.

  16. What are the benefits and risks of fitting patients with radiofrequency identification devices.

    Science.gov (United States)

    Levine, Mark; Adida, Ben; Mandl, Kenneth; Kohane, Isaac; Halamka, John

    2007-11-27

    In 2004, the United States Food and Drug Administration approved a radiofrequency identification (RFID) device that is implanted under the skin of the upper arm of patients and that stores the patient's medical identifier. When a scanner is passed over the device, the identifier is displayed on the screen of an RFID reader. An authorized health professional can then use the identifier to access the patient's clinical information, which is stored in a separate, secure database. Such RFID devices may have many medical benefits--such as expediting identification of patients and retrieval of their medical records. But critics of the technology have raised several concerns, including the risk of the patient's identifying information being used for nonmedical purposes.

  17. Fuel cladding tube leak detection device

    International Nuclear Information System (INIS)

    Naito, Makoto.

    1992-01-01

    The device of the present invention can detect even a minute leakage or a continuous leakage during reactor operation. That is, the device of the present invention comprises a detector for analyzing nuclides of gases incorporated in a gas waste processing system, and a calculation device connected to the detector and detecting leakage from a fuel cladding tube by calculation for variation coefficient of long-life nuclides. By using theses devices, radioactivity contained in gases incorporated in the gas waste processing system is analyzed for the nuclides. Among the analized nuclides, if the amount of the long-life nuclides exceeds a predetermined value, it is judged as leakage of the fuel cladding tube. For example, the long-life nuclides include Xe-133. The device of the present invention can certainly detect occurrence of leakage even when it is minute or continues leakage. Accordingly, countermeasures can be taken in an early stage, thereby enabling to contribute improvement for the safety of a nuclear power plant. (I.S.)

  18. Rapid Electrochemical Detection and Identification of Microbiological and Chemical Contaminants for Manned Spaceflight Project

    Science.gov (United States)

    Pierson, Duane; Botkin, Douglas; Gazda, Daniel

    2014-01-01

    Microbial control in the spacecraft environment is a daunting task, especially in the presence of human crew members. Currently, assessing the potential crew health risk associated with a microbial contamination event requires return of representative environmental samples that are analyzed in a ground-based laboratory. It is therefore not currently possible to quickly identify microbes during spaceflight. This project addresses the unmet need for spaceflight-compatible microbial identification technology. The electrochemical detection and identification platform is expected to provide a sensitive, specific, and rapid sample-to-answer capability for in-flight microbial monitoring that can distinguish between related microorganisms (pathogens and non-pathogens) as well as chemical contaminants. This will dramatically enhance our ability to monitor the spacecraft environment and the health risk to the crew. Further, the project is expected to eliminate the need for sample return while significantly reducing crew time required for detection of multiple targets. Initial work will focus on the optimization of bacterial detection and identification. The platform is designed to release nucleic acids (DNA and RNA) from microorganisms without the use of harmful chemicals. Bacterial DNA or RNA is captured by bacteria-specific probe molecules that are bound to a microelectrode, and that capture event can generate a small change in the electrical current (Lam, et al. 2012. Anal. Chem. 84(1): 21-5.). This current is measured, and a determination is made whether a given microbe is present in the sample analyzed. Chemical detection can be accomplished by directly applying a sample to the microelectrode and measuring the resulting current change. This rapid microbial and chemical detection device is designed to be a low-cost, low-power platform anticipated to be operated independently of an external power source, characteristics optimal for manned spaceflight and areas where power

  19. 78 FR 58785 - Unique Device Identification System

    Science.gov (United States)

    2013-09-24

    ... the UDI system because they are controlled in the supply chain by the kit rather than by constituent... reduce existing obstacles to the adequate identification of medical devices used in the United States. By... stated, ``We support FDA's objective to substantially reduce existing obstacles to the adequate...

  20. Exploration of Uninitialized Configuration Memory Space for Intrinsic Identification of Xilinx Virtex-5 FPGA Devices

    Directory of Open Access Journals (Sweden)

    Oliver Sander

    2012-01-01

    Full Text Available SRAM-based fingerprinting uses deviations in power-up behaviour caused by the CMOS fabrication process to identify distinct devices. This method is a promising technique for unique identification of physical devices. In the case of SRAM-based hardware reconfigurable devices such as FPGAs, the integrated SRAM cells are often initialized automatically at power-up, sweeping potential identification data. We demonstrate an approach to utilize unused parts of configuration memory space for device identification. Based on a total of over 200,000 measurements on nine Xilinx Virtex-5 FPGAs, we show that the retrieved values have promising properties with respect to consistency on one device, variety between different devices, and stability considering temperature variation and aging.

  1. What are the benefits and risks of fitting patients with radiofrequency identification devices.

    Directory of Open Access Journals (Sweden)

    Mark Levine

    2007-11-01

    Full Text Available In 2004, the United States Food and Drug Administration approved a radiofrequency identification (RFID device that is implanted under the skin of the upper arm of patients and that stores the patient's medical identifier. When a scanner is passed over the device, the identifier is displayed on the screen of an RFID reader. An authorized health professional can then use the identifier to access the patient's clinical information, which is stored in a separate, secure database. Such RFID devices may have many medical benefits--such as expediting identification of patients and retrieval of their medical records. But critics of the technology have raised several concerns, including the risk of the patient's identifying information being used for nonmedical purposes.

  2. System-on-fluidics immunoassay device integrating wireless radio-frequency-identification sensor chips.

    Science.gov (United States)

    Yazawa, Yoshiaki; Oonishi, Tadashi; Watanabe, Kazuki; Shiratori, Akiko; Funaoka, Sohei; Fukushima, Masao

    2014-09-01

    A simple and sensitive point-of-care-test (POCT) device for chemiluminescence (CL) immunoassay was devised and tested. The device consists of a plastic flow-channel reactor and two wireless-communication sensor chips, namely, a photo-sensor chip and a temperature-sensor chip. In the flow-channel reactor, a target antigen is captured by an antibody immobilized on the inner wall of the flow-channel and detected with enzyme labeled antibody by using CL substrate. The CL signal corresponding to the amount of antigen is measured by a newly developed radio-frequency-identification (RFID) sensor, which enables batteryless operation and wireless data communication with an external reader. As for the POCT device, its usage environment, especially temperature, varies for each measurement. Hence, temperature compensation is a key issue in regard to eliminating dark-signal fluctuation, which is a major factor in deterioration of the precision of the POCT device. A two-stage temperature-compensation scheme was adopted. As for the first stage, the signals of two photodiodes, one with an open window and one with a sealed window, integrated on the photo-sensor chip are differentiated to delete the dark signal. As for the second stage, the differentiated signal fluctuation caused by a temperature variation is compensated by using the other sensor chip (equipped with a temperature sensor). The dark-level fluctuation caused by temperature was reduced from 0.24 to 0.02 pA/°C. The POCT device was evaluated as a CL immunoassay of thyroid-stimulating hormone (TSH). The flow rate of the CL reagent in the flow channel was optimized. As a result, the detection limit of the POCT device was 0.08 ng/ml (i.e., 0.4 μIU/ml). Copyright © 2014 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

  3. Physics-based mathematical models for quantum devices via experimental system identification

    Energy Technology Data Exchange (ETDEWEB)

    Schirmer, S G; Oi, D K L; Devitt, S J [Department of Applied Maths and Theoretical Physics, University of Cambridge, Wilberforce Rd, Cambridge, CB3 0WA (United Kingdom); SUPA, Department of Physics, University of Strathclyde, Glasgow G4 0NG (United Kingdom); National Institute of Informatics, 2-1-2 Hitotsubashi, Chiyoda-ku, Tokyo 101-8430 (Japan)], E-mail: sgs29@cam.ac.uk

    2008-03-15

    We consider the task of intrinsic control system identification for quantum devices. The problem of experimental determination of subspace confinement is considered, and simple general strategies for full Hamiltonian identification and decoherence characterization of a controlled two-level system are presented.

  4. [Development of molecular detection of food-borne pathogenic bacteria using miniaturized microfluidic devices].

    Science.gov (United States)

    Iván, Kristóf; Maráz, Anna

    2015-12-20

    Detection and identification of food-borne pathogenic bacteria are key points for the assurance of microbiological food safety. Traditional culture-based methods are more and more replaced by or supplemented with nucleic acid based molecular techniques, targeting specific (preferably virulence) genes in the genomes. Internationally validated DNA amplification - most frequently real-time polymerase chain reaction - methods are applied by the food microbiological testing laboratories for routine analysis, which will result not only in shortening the time for results but they also improve the performance characteristics (e.g. sensitivity, specificity) of the methods. Beside numerous advantages of the polymerase chain reaction based techniques for routine microbiological analysis certain drawbacks have to be mentioned, such as the high cost of the equipment and reagents, as well as the risk of contamination of the laboratory environment by the polymerase chain reaction amplicons, which require construction of an isolated laboratory system. Lab-on-a-chip systems can integrate most of these laboratory processes within a miniaturized device that delivers the same specificity and reliability as the standard protocols. The benefits of miniaturized devices are: simple - often automated - use, small overall size, portability, sterility due to single use possibility. These miniaturized rapid diagnostic tests are being researched and developed at the best research centers around the globe implementing various sample preparation and molecular DNA amplification methods on-chip. In parallel, the aim of the authors' research is to develop microfluidic Lab-on-a-chip devices for the detection and identification of food-borne pathogenic bacteria.

  5. Flaw detection device for plasma facing wall in thermonuclear device

    International Nuclear Information System (INIS)

    Doi, Akira.

    1996-01-01

    The present invention concerns plasma facing walls of a thermonuclear device and provides a device for detecting a thickness of amour tiles accurately and efficiently with no manual operation. Namely, the position of the plasma facing surface of the amour tile is measured using a structure to which the amour tiles are to be disposed as a reference. Also in a case of disposing new armor tiles, the position of the plasma facing surface of the armor tiles is measured to thereby measure the wearing amount of the amour tiles based on the difference between the reference and the measured value. If a measuring means capable of measuring a plurality of amour tiles at once is used efficiency of the measurement and the detection can be enhanced. Several ten thousands of amour tiles are disposed to the plasma facing wall in a large scaled thermonuclear device, and a plenty of time was required for the detection. However, the present invention can improve the accuracy for the measurement and detection and provide time and labors-saving. (I.S.)

  6. Radiation sensitive area detection device and method

    Science.gov (United States)

    Carter, Daniel C. (Inventor); Hecht, Diana L. (Inventor); Witherow, William K. (Inventor)

    1991-01-01

    A radiation sensitive area detection device for use in conjunction with an X ray, ultraviolet or other radiation source is provided which comprises a phosphor containing film which releases a stored diffraction pattern image in response to incoming light or other electromagnetic wave. A light source such as a helium-neon laser, an optical fiber capable of directing light from the laser source onto the phosphor film and also capable of channelling the fluoresced light from the phosphor film to an integrating sphere which directs the light to a signal processing means including a light receiving means such as a photomultiplier tube. The signal processing means allows translation of the fluoresced light in order to detect the original pattern caused by the diffraction of the radiation by the original sample. The optical fiber is retained directly in front of the phosphor screen by a thin metal holder which moves up and down across the phosphor screen and which features a replaceable pinhole which allows easy adjustment of the resolution of the light projected onto the phosphor film. The device produces near real time images with high spatial resolution and without the distortion that accompanies prior art devices employing photomultiplier tubes. A method is also provided for carrying out radiation area detection using the device of the invention.

  7. Scan direction induced charging dynamics and the application for detection of gate to S/D shorts in logic devices

    Science.gov (United States)

    Lei, Ming; Tian, Qing; Wu, Kevin; Zhao, Yan

    2016-03-01

    Gate to source/drain (S/D) short is the most common and detrimental failure mechanism for advanced process technology development in Metal-Oxide-Semiconductor-Field-Effect-Transistor (MOSFET) device manufacturing. Especially for sub-1Xnm nodes, MOSFET device is more vulnerable to gate-S/D shorts due to the aggressive scaling. The detection of this kind of electrical short defect is always challenging for in-line electron beam inspection (EBI), especially new shorting mechanisms on atomic scale due to new material/process flow implementation. The second challenge comes from the characterization of the shorts including identification of the exact shorting location. In this paper, we demonstrate unique scan direction induced charging dynamics (SDCD) phenomenon which stems from the transistor level response from EBI scan at post metal contact chemical-mechanical planarization (CMP) layers. We found that SDCD effect is exceptionally useful for gate-S/D short induced voltage contrast (VC) defect detection, especially for identification of shorting locations. The unique SDCD effect signatures of gate-S/D shorts can be used as fingerprint for ground true shorting defect detection. Correlation with other characterization methods on the same defective location from EBI scan shows consistent results from various shorting mechanism. A practical work flow to implement the application of SDCD effect for in-line EBI monitor of critical gate-S/D short defects is also proposed, together with examples of successful application use cases which mostly focus on static random-access memory (SRAM) array regions. Although the capability of gate-S/D short detection as well as expected device response is limited to passing transistors and pull-down transistors due to the design restriction from standard 6-cell SRAM structure, SDCD effect is proven to be very effective for gate-S/D short induced VC defect detection as well as yield learning for advanced technology development.

  8. Structural Acoustic UXO Detection and Identification in Marine Environments

    Science.gov (United States)

    2016-05-01

    a thick steel wall, is cylindrical, and has an aspect ratio of about 5:1. Further, the interior water can support acoustic waves as does the epoxy...FINAL REPORT Structural Acoustic UXO Detection and Identification in Marine Environments SERDP Project MR-2103 MAY 2016 B. H...NUMBER Structural Acoustic UXO Detection and Identification in Marine Environments- Final report for Follow-on Work- MR-2103 Sb. GRANT NUMBER Sc

  9. Nuclear-burst strength detecting and measuring device

    International Nuclear Information System (INIS)

    Balut, J.A.L.G.; Lemaire, P.E.G.K.; Loisy, C.M.

    1976-01-01

    A continuous-operation automatic device is described for detection and accurate measurement of the strength of a burst generating an emission from luminous or infrared sources. This device characterizes and analyzes the maxima and minima of a ''thermal flux/time'' curve. The device comprises a master time element and an assembly of photoelectric detectors, an electronic processing system coupled to the detectors, and a mechanical system securing the rigidity and positioning of the photoelectric detector assembly with respect to an octahedral prism based on a horizontal plane

  10. Sample preparation and detection device for infectious agents

    Science.gov (United States)

    Miles, Robin R.; Wang, Amy W.; Fuller, Christopher K.; Lemoff, Asuncion V.; Bettencourt, Kerry A.; Yu, June

    2003-06-10

    A sample preparation and analysis device which incorporates both immunoassays and PCR assays in one compact, field-portable microchip. The device provides new capabilities in fluid and particle control which allows the building of a fluidic chip with no moving parts, thus decreasing fabrication cost and increasing the robustness of the device. The device can operate in a true continuous (not batch) mode. The device incorporates magnetohydrodynamic (MHD) pumps to move the fluid through the system, acoustic mixing and fractionation, dielectropheretic (DEP) sample concentration and purification, and on-chip optical detection capabilities.

  11. Pressure detection device

    International Nuclear Information System (INIS)

    Fuji, Akira.

    1997-01-01

    The present invention provides a pressure detection device having a function of preventing discharge of reactor water in pipelines to the outside of a system when a pipeline for detecting pressure to be connected to a reactor is failed. Namely, a fluid pressure detector is disposed at the downstream of the detection pipeline. A cylindrical member having a shrinkable inner diameter is disposed to the outer circumference at the upstream. A cylindrical member having an outer diameter substantially equal to the inner diameter of the detection pipeline is disposed while restricting the movement of the detection pipeline in the inner circumferential direction. Then, it fasten the detection pipeline from the outside upon failure of the pipeline thereby enabling to suppress the flow rate of the fluid in the detection pipeline. In addition, a shape memory alloy which shrinks upon elevation of temperature is used for the cylindrical member. Then, the discharge of the fluid can be prevented automatically upon rupture of the pipeline. (I.S.)

  12. A wearable device for a fully automated in-hospital staff and patient identification.

    Science.gov (United States)

    Cavalleri, M; Morstabilini, R; Reni, G

    2004-01-01

    In the health care context, devices for automated staff / patient identification provide multiple benefits, including error reduction in drug administration, an easier and faster use of the Electronic Health Record, enhanced security and control features when accessing confidential data, etc. Current identification systems (e.g. smartcards, bar codes) are not completely seamless to users and require mechanical operations that sometimes are difficult to perform for impaired subjects. Emerging wireless RFID technologies are encouraging, but cannot still be introduced in health care environments due to their electromagnetic emissions and the need for large size antenna to operate at reasonable distances. The present work describes a prototype of wearable device for automated staff and patient identification which is small in size and complies with the in-hospital electromagnetic requirements. This prototype also implements an anti-counterfeit option. Its experimental application allowed the introduction of some security functions for confidential data management.

  13. Load power device, system and method of load control and management employing load identification

    Science.gov (United States)

    Yang, Yi; Luebke, Charles John; Schoepf, Thomas J.

    2018-01-09

    A load power device includes a power input, at least one power output for at least one load, a plurality of sensors structured to sense voltage and current at the at least one power output, and a processor. The processor provides: (a) load identification based upon the sensed voltage and current, and (b) load control and management based upon the load identification.

  14. 9 CFR 354.2 - Designation of official certificates, memoranda, marks, other identifications, and devices for...

    Science.gov (United States)

    2010-01-01

    ..., memoranda, marks, other identifications, and devices for purposes of the Agricultural Marketing Act. 354.2... Agricultural Marketing Act. Subsection 203(h) of the Agricultural Marketing Act of 1946, as amended by Pub. L... device means a stamping appliance, branding device, stencil, printed label, or any other mechanically or...

  15. Development of failure-detecting device for γ radioimmunoassay counter

    International Nuclear Information System (INIS)

    Shao Xianzhi; Zhang Bingfeng

    1997-01-01

    A failures-detecting device based on single chip microcomputer technique for detecting of failures of γ radioimmunoassay counter is developed. The device can output signals of variable amplitude and frequency similar to the pulse of γ particle for shooting problem parts of γ counter's detecting system. By automatically comparing the shapes and amplitudes of the two signals to and from an amplifier unit, the device can distinguish if the amplifier unit works normally. The differential-input amplifier circuit gives 0.1% accuracy for the measurement of the stability of high voltage. The pulse widen circuit of this device allows for middle speed A/D detecting of periodical low-frequency pulse waves of micro-second width. This device is used specifically for the maintaining and failure-detecting of γ radioimmunoassay counter

  16. Self compensating fire detection device

    International Nuclear Information System (INIS)

    Cholin, J. M.

    1985-01-01

    A device employing ionization principles for fire detection disclosing a configuration which allows compensation for adverse effects due to the flow of the gas through the device or due to the accumulation of dust and dirt therein. The detecting device includes two ionization chambers, each having a first member, such as a cylindrically shaped cup, having first and second conductive surface portions. Each chamber also incudes a second member, such as a circular, electrode disc having two conductive surface portions. There is disposed in each chamber a radioactive source for ionizing the gas in the volumes intervening between respective pairs of surfaces. The area dimensions of the respective pairs of surfaces, the interventing volumes and the distances there between, and the relative orientation of the respective pairs are calculated and placed such that the ionization currents flowing between pairs of conductive surfaces are substantially equal and orthogonal to each other

  17. An on-line identification device for coal and gangue based on dual-energy γ-ray transmission and microcontroller

    International Nuclear Information System (INIS)

    Chen Guojie; Zhu Xing

    2004-01-01

    The operating principle, hardware design, software design and stabled-spectrum method of on-line identification device for coal and gangue based on dual-energy γ-ray transmission and microcontroller are introduced. The integrated linear amplifier and integrated single channel pulse height analyzer are analyzed. The on-line identification device has advantages of small size, low cost as well stabilization. (authors)

  18. Silicon solid state devices and radiation detection

    CERN Document Server

    Leroy, Claude

    2012-01-01

    This book addresses the fundamental principles of interaction between radiation and matter, the principles of working and the operation of particle detectors based on silicon solid state devices. It covers a broad scope with respect to the fields of application of radiation detectors based on silicon solid state devices from low to high energy physics experiments including in outer space and in the medical environment. This book covers stateof- the-art detection techniques in the use of radiation detectors based on silicon solid state devices and their readout electronics, including the latest developments on pixelated silicon radiation detector and their application.

  19. Investigating User Identification in Remote Patient Monitoring Devices.

    Science.gov (United States)

    Ondiege, Brian; Clarke, Malcolm

    2017-09-13

    With the increase in the number of people having a chronic disease, there is an increase in households having more than a single person suffering from the same chronic illness. One problem of monitoring such patients in their own home is that current devices have a limitation in the number of people who can use a single device. This study investigates the use of Near Field Communication (NFC) for identification in a multi-user environment. A mixed-method qualitative and quantitative approach was adopted, including focus groups, observations and a field trial. Data were collected in three phases. In Phase 1, five focus groups were conducted with patients to determine their beliefs, concerns and issues with using identification in remote patient monitoring devices. In Phase 2, participants were given a blood pressure monitor modified to include an NFC reader to enable identification. The modified device was given to patients living as a couple in the same household and both suffering from hypertension. Both patients used the device for a period of two weeks to observe their acceptance of the technology and determine their experience of usage. A total of 40 (20 couples) patients participated in the trial. Non-adherence to the full monitoring regimen was low and was mainly due to usability issues or commitments taking them away from the home and thus unable to take readings. After the trial period participants were invited to discuss their experiences with the technology in a focus group discussion (Phase 3), a total of five focus groups were conducted. Focus group discussions with the patients revealed that most participants liked using the system and were not apprehensive towards Healthcare Information Technology (HIT). The participants also had suggestions for improvements that could be made to the modified blood pressure monitor (such as, rechargeable in place batteries, integrate the components, easier to use cuff, and increased sensitivity of the NFC reader) that

  20. Medical Devices; Immunology and Microbiology Devices; Classification of the Device To Detect and Identify Microbial Pathogen Nucleic Acids in Cerebrospinal Fluid. Final order.

    Science.gov (United States)

    2017-10-20

    The Food and Drug Administration (FDA or we) is classifying the device to detect and identify microbial pathogen nucleic acids in cerebrospinal fluid into class II (special controls). The special controls that will apply to the device type are identified in this order and will be part of the codified language for the device to detect and identify microbial pathogen nucleic acids in cerebrospinal fluid’s classification. We are taking this action because we have determined that classifying the device into class II (special controls) will provide a reasonable assurance of safety and effectiveness of the device. We believe this action will also enhance patients' access to beneficial innovative devices, in part by reducing regulatory burdens.

  1. A Portable, Air-Jet-Actuator-Based Device for System Identification

    Science.gov (United States)

    Staats, Wayne; Belden, Jesse; Mazumdar, Anirban; Hunter, Ian

    2010-11-01

    System identification (ID) of human and robotic limbs could help in diagnosis of ailments and aid in optimization of control parameters and future redesigns. We present a self-contained actuator, which uses the Coanda effect to rapidly switch the direction of a high speed air jet to create a binary stochastic force input to a limb for system ID. The design of the actuator is approached with the goal of creating a portable device, which could deployed on robot or human limbs for in situ identification. The viability of the device is demonstrated by performing stochastic system ID on an underdamped elastic beam system with fixed inertia and stiffness, and variable damping. The non-parametric impulse response yielded from the stochastic system ID is modeled as a second order system, and the resultant parameters are found to be in excellent agreement with those found using more traditional system ID techniques. The current design could be further miniaturized and developed as a portable, wireless, on-site multi-axis system identification system for less intrusive and more widespread use.

  2. Efficient Signature Based Malware Detection on Mobile Devices

    Directory of Open Access Journals (Sweden)

    Deepak Venugopal

    2008-01-01

    Full Text Available The threat of malware on mobile devices is gaining attention recently. It is important to provide security solutions to these devices before these threats cause widespread damage. However, mobile devices have severe resource constraints in terms of memory and power. Hence, even though there are well developed techniques for malware detection on the PC domain, it requires considerable effort to adapt these techniques for mobile devices. In this paper, we outline the considerations for malware detection on mobile devices and propose a signature based malware detection method. Specifically, we detail a signature matching algorithm that is well suited for use in mobile device scanning due to its low memory requirements. Additionally, the matching algorithm is shown to have high scanning speed which makes it unobtrusive to users. Our evaluation and comparison study with the well known Clam-AV scanner shows that our solution consumes less than 50% of the memory used by Clam-AV while maintaining a fast scanning rate.

  3. A Framework for Counterfeit Smart Grid Device Detection

    Energy Technology Data Exchange (ETDEWEB)

    Babun, Leonardo [Florida Intl Univ., Miami, FL (United States); Aksu, Hidayet [Florida Intl Univ., Miami, FL (United States); Uluagac, A. Selcuk [Florida Intl Univ., Miami, FL (United States)

    2016-10-19

    The core vision of the smart grid concept is the realization of reliable two-­way communications between smart devices (e.g., IEDs, PLCs, PMUs). The benefits of the smart grid also come with tremendous security risks and new challenges in protecting the smart grid systems from cyber threats. Particularly, the use of untrusted counterfeit smart grid devices represents a real problem. Consequences of propagating false or malicious data, as well as stealing valuable user or smart grid state information from counterfeit devices are costly. Hence, early detection of counterfeit devices is critical for protecting smart grid’s components and users. To address these concerns, in this poster, we introduce our initial design of a configurable framework that utilize system call tracing, library interposition, and statistical techniques for monitoring and detection of counterfeit smart grid devices. In our framework, we consider six different counterfeit device scenarios with different smart grid devices and adversarial seZings. Our initial results on a realistic testbed utilizing actual smart-­grid GOOSE messages with IEC-­61850 communication protocol are very promising. Our framework is showing excellent rates on detection of smart grid counterfeit devices from impostors.

  4. A safety control device for detecting undesirable conditions

    Energy Technology Data Exchange (ETDEWEB)

    1974-09-26

    The invention relates to safety control devices. It deals with a device adapted to transmit a warning signal and to the detection of an undesirable condition in an associated apparatus, said device comprising switching means comprising transistors mounted in a reaction path, feeding means for opening the switching means whenever an undesirable condition has been detected by sensors, whereby an oscillator is caused to stop oscillating, and an outlet device controlled by the oscillator stoppage. This can be applied to the supervision of nuclear reactor.

  5. Supersonic flaw detection device for nozzle

    International Nuclear Information System (INIS)

    Hata, Moriki.

    1996-01-01

    In a supersonic flaw detection device to be attached to a body surface of a reactor pressure vessel for automatically detecting flaws of a welded portion of a horizontally connected nozzle by using supersonic waves, a running vehicle automatically running along a circumferential direction of the nozzle comprises a supersonic flaw detection means for detecting flaws of the welded portion of the nozzle by using supersonic waves, and an inclination angle sensor for detecting the inclination angle of the running vehicle relative to the central axis of the nozzle. The running distance of the vehicle running along the circumference of the nozzle, namely, the position of the running vehicle from a reference point of the nozzle can be detected accurately by dividing the distance around the nozzle by the inclination angle detected by the inclination angle sensor. Accordingly, disadvantages in the prior art, for example, that the detected values obtained by using an encoder are changed by slipping or idle running of the magnet wheels are eliminated, and accurate flaw detection can be conducted. In addition, an operation of visually adjusting the reference point for the device can be eliminated. An operator's exposure dose can be reduced. (N.H.)

  6. Detection and Identification of Loss of Efficiency Faults of Flight Actuators

    Directory of Open Access Journals (Sweden)

    Ossmann Daniel

    2015-03-01

    Full Text Available We propose linear parameter-varying (LPV model-based approaches to the synthesis of robust fault detection and diagnosis (FDD systems for loss of efficiency (LOE faults of flight actuators. The proposed methods are applicable to several types of parametric (or multiplicative LOE faults such as actuator disconnection, surface damage, actuator power loss or stall loads. For the detection of these parametric faults, advanced LPV-model detection techniques are proposed, which implicitly provide fault identification information. Fast detection of intermittent stall loads (seen as nuisances, rather than faults is important in enhancing the performance of various fault detection schemes dealing with large input signals. For this case, a dedicated fast identification algorithm is devised. The developed FDD systems are tested on a nonlinear actuator model which is implemented in a full nonlinear aircraft simulation model. This enables the validation of the FDD system’s detection and identification characteristics under realistic conditions.

  7. Error-Detecting Identification Codes for Algebra Students.

    Science.gov (United States)

    Sutherland, David C.

    1990-01-01

    Discusses common error-detecting identification codes using linear algebra terminology to provide an interesting application of algebra. Presents examples from the International Standard Book Number, the Universal Product Code, bank identification numbers, and the ZIP code bar code. (YP)

  8. Radiation sensitive devices and systems for detection of radioactive materials and related methods

    Science.gov (United States)

    Kotter, Dale K

    2014-12-02

    Radiation sensitive devices include a substrate comprising a radiation sensitive material and a plurality of resonance elements coupled to the substrate. Each resonance element is configured to resonate responsive to non-ionizing incident radiation. Systems for detecting radiation from a special nuclear material include a radiation sensitive device and a sensor located remotely from the radiation sensitive device and configured to measure an output signal from the radiation sensitive device. In such systems, the radiation sensitive device includes a radiation sensitive material and a plurality of resonance elements positioned on the radiation sensitive material. Methods for detecting a presence of a special nuclear material include positioning a radiation sensitive device in a location where special nuclear materials are to be detected and remotely interrogating the radiation sensitive device with a sensor.

  9. Detection and identification of human targets in radar data

    Science.gov (United States)

    Gürbüz, Sevgi Z.; Melvin, William L.; Williams, Douglas B.

    2007-04-01

    Radar offers unique advantages over other sensors, such as visual or seismic sensors, for human target detection. Many situations, especially military applications, prevent the placement of video cameras or implantment seismic sensors in the area being observed, because of security or other threats. However, radar can operate far away from potential targets, and functions during daytime as well as nighttime, in virtually all weather conditions. In this paper, we examine the problem of human target detection and identification using single-channel, airborne, synthetic aperture radar (SAR). Human targets are differentiated from other detected slow-moving targets by analyzing the spectrogram of each potential target. Human spectrograms are unique, and can be used not just to identify targets as human, but also to determine features about the human target being observed, such as size, gender, action, and speed. A 12-point human model, together with kinematic equations of motion for each body part, is used to calculate the expected target return and spectrogram. A MATLAB simulation environment is developed including ground clutter, human and non-human targets for the testing of spectrogram-based detection and identification algorithms. Simulations show that spectrograms have some ability to detect and identify human targets in low noise. An example gender discrimination system correctly detected 83.97% of males and 91.11% of females. The problems and limitations of spectrogram-based methods in high clutter environments are discussed. The SNR loss inherent to spectrogram-based methods is quantified. An alternate detection and identification method that will be used as a basis for future work is proposed.

  10. Failed fuel detection device

    International Nuclear Information System (INIS)

    Sudo, Takayuki.

    1983-01-01

    Purpose: To enable early and sure detection of failed fuels by automatically changing the alarm set value depending on the operation states of a nuclear reactor. Constitution: Gaseous fission products released into coolants are transferred further into cover gases and then introduced through a pipeway to a failed fuel detector. The cover gases introduced from the pipeway to the pipeway or chamber within the detection device are detected by a radiation detector for the radiation dose of the gaseous fission products contained therein. The detected value is converted and amplified as a signal and inputted to a comparator. While on the other hand, a signal corresponding to the reactor power is converted by an alarm setter into a set value and inputted to the comparator. In such a structure, early and sure detection can be made for the fuel failures. (Yoshino, Y.)

  11. Design of a leak detection device for marine airtight container

    Science.gov (United States)

    Li, Yuan; Zhu, Faxin; Lu, Jinshu; Li, Yule; Wu, Wenfeng; Zhang, Jianwei; Qin, Beichen

    2018-04-01

    The ship airtight container as the research object, according to the tightness of the traditional detection methods of sealed container from the shortcomings of the design of modern ship sealed container leak detection device based on the requirements of the use of AutoCAD to design a ship leakage detection device using airtight container, and introduces its working principle and main components. Finally, from the aspects of technology, structure, operation and economy, the feasibility analysis of the leak detection device for marine airtight container is designed, and it is concluded that the device has the advantages of simple operation, short detection time, easy maintenance and cost control, and has high feasibility.

  12. Radiation detection and measurement concepts, methods and devices

    CERN Document Server

    McGregor, Douglas

    2019-01-01

    This text on radiation detection and measurement is a response to numerous requests expressed by students at various universities, in which the most popularly used books do not provide adequate background material, nor explain matters in understandable terms. This work provides a modern overview of radiation detection devices and radiation measurement methods. The topics selected in the book have been selected on the basis of the author’s many years of experience designing radiation detectors and teaching radiation detection and measurement in a classroom environment.

  13. Authentication of Radio Frequency Identification Devices Using Electronic Characteristics

    Science.gov (United States)

    Chinnappa Gounder Periaswamy, Senthilkumar

    2010-01-01

    Radio frequency identification (RFID) tags are low-cost devices that are used to uniquely identify the objects to which they are attached. Due to the low cost and size that is driving the technology, a tag has limited computational capabilities and resources. This limitation makes the implementation of conventional security protocols to prevent…

  14. Multi-chamber nucleic acid amplification and detection device

    Science.gov (United States)

    Dugan, Lawrence

    2017-10-25

    A nucleic acid amplification and detection device includes an amplification cartridge with a plurality of reaction chambers for containing an amplification reagent and a visual detection reagent, and a plurality of optically transparent view ports for viewing inside the reaction chambers. The cartridge also includes a sample receiving port which is adapted to receive a fluid sample and fluidically connected to distribute the fluid sample to the reaction chamber, and in one embodiment, a plunger is carried by the cartridge for occluding fluidic communication to the reaction chambers. The device also includes a heating apparatus having a heating element which is activated by controller to generate heat when a trigger event is detected. The heating apparatus includes a cartridge-mounting section which positioned a cartridge in thermal communication with the heating element so that visual changes to the contents of the reaction chambers are viewable through the view ports.

  15. MedMon: securing medical devices through wireless monitoring and anomaly detection.

    Science.gov (United States)

    Zhang, Meng; Raghunathan, Anand; Jha, Niraj K

    2013-12-01

    Rapid advances in personal healthcare systems based on implantable and wearable medical devices promise to greatly improve the quality of diagnosis and treatment for a range of medical conditions. However, the increasing programmability and wireless connectivity of medical devices also open up opportunities for malicious attackers. Unfortunately, implantable/wearable medical devices come with extreme size and power constraints, and unique usage models, making it infeasible to simply borrow conventional security solutions such as cryptography. We propose a general framework for securing medical devices based on wireless channel monitoring and anomaly detection. Our proposal is based on a medical security monitor (MedMon) that snoops on all the radio-frequency wireless communications to/from medical devices and uses multi-layered anomaly detection to identify potentially malicious transactions. Upon detection of a malicious transaction, MedMon takes appropriate response actions, which could range from passive (notifying the user) to active (jamming the packets so that they do not reach the medical device). A key benefit of MedMon is that it is applicable to existing medical devices that are in use by patients, with no hardware or software modifications to them. Consequently, it also leads to zero power overheads on these devices. We demonstrate the feasibility of our proposal by developing a prototype implementation for an insulin delivery system using off-the-shelf components (USRP software-defined radio). We evaluate its effectiveness under several attack scenarios. Our results show that MedMon can detect virtually all naive attacks and a large fraction of more sophisticated attacks, suggesting that it is an effective approach to enhancing the security of medical devices.

  16. Detection and identification of unexploded ordnance (UXO) by neutron interrogation

    International Nuclear Information System (INIS)

    Caffrey, A.J.; Hartwell, J.K.; Krebs, K.M.; McLaughlin, G.D.

    1998-01-01

    This document reviews the principle of operation and unexploded ordnance (UXO) signatures of the PINS Chemical Assay System, a prompt-gamma-ray neutron activation analysis (PGNAA) for the identification of recovered UXO. Two related low cost methods for buried landmine detection are also suggested. Nuclear methods may compliment existing search techniques to improve the overall probability of detection and to reduce the false positive rate of other technologies. In addition, nuclear methods are a proven method for identification of UXO such as landmines

  17. X ray sensitive area detection device

    Science.gov (United States)

    Carter, Daniel C. (Inventor); Witherow, William K. (Inventor); Pusey, Marc L. (Inventor); Yost, Vaughn H. (Inventor)

    1990-01-01

    A radiation sensitive area detection device is disclosed which comprises a phosphor-containing film capable of receiving and storing an image formed by a pattern of incoming x rays, UV, or other radiation falling on the film. The device is capable of fluorescing in response to stimulation by a light source in a manner directly proportional to the stored radiation pattern. The device includes: (1) a light source capable of projecting light or other appropriate electromagnetic wave on the film so as to cause it to fluoresce; (2) a means to focus the fluoresced light coming from the phosphor-containing film after light stimulation; and (3) at least one charged coupled detector or other detecting element capable of receiving and digitizing the pattern of fluoresced light coming from the phosphor-containing film. The device will be able to generate superior x ray images of high resolution from a crystal or other sample and will be particularly advantageous in that instantaneous near-real-time images of rapidly deteriorating samples can be obtained. Furthermore, the device can be made compact and sturdy, thus capable of carrying out x ray or other radiation imaging under a variety of conditions, including those experienced in space.

  18. Detection device for inside of space

    International Nuclear Information System (INIS)

    Kojima, Kosuke.

    1996-01-01

    A securing plate is disposed to a support column which can be inserted to a space, and a rotational member on which equipments for detection are loaded is disposed rotatably in the longitudinal direction of the support column at a predetermined distance from the securing plate. Shape memory alloy wires that shrink when current is supplied are stretched circumferentially each at a predetermined distance obliquely relative to the support column between the rotational member and the securing plate. In addition, there are disposed a sensor for detecting the rotational angle of the rotational member, a calculator for determining the deviation of the angle of the rotation based on the difference of the detected rotational angle and a predetermined rotational angle as a reference, a deviation counter for obtaining deviation count signals based on the deviation of the rotational angle, a D-A convertor for converting the deviation count signals to analog signals, a pulse width modulation device for duty ratio control based on the analog signals and output pulse signals, and a power amplifier for amplifying the pulse signals and applying them to the shape memory wires. Since the device is reduced in the size and weight, handling is facilitated, and the rotational angle can be controlled accurately. The device can be used for detection of an end plate in a pressure vessel. (N.H.)

  19. Supersonic wave detection method and supersonic detection device

    International Nuclear Information System (INIS)

    Machida, Koichi; Seto, Takehiro; Ishizaki, Hideaki; Asano, Rin-ichi.

    1996-01-01

    The present invention provides a method of and device for a detection suitable to a channel box which is used while covering a fuel assembly of a BWR type reactor. Namely, a probe for transmitting/receiving supersonic waves scans on the surface of the channel box. A data processing device determines an index showing a selective orientation degree of crystal direction of the channel box based on the signals received by the probe. A judging device compares the determined index with a previously determined allowable range to judge whether the channel box is satisfactory or not based on the result of the comparison. The judgement are on the basis that (1) the bending of the channel box is caused by the difference of elongation of opposed surfaces, (2) the elongation due to irradiation is caused by the selective orientation of crystal direction, and (3) the bending of the channel box can be suppressed within a predetermined range by suppressing the index determined by the measurement of supersonic waves having a correlation with the selective orientation of the crystal direction. As a result, the performance of the channel box capable of enduring high burnup region can be confirmed in a nondestructive manner. (I.S.)

  20. Microfluidic devices for sample preparation and rapid detection of foodborne pathogens

    DEFF Research Database (Denmark)

    Kant, Krishna; Shahbazi, Mohammad-Ali; Dave, Vivek Priy

    2018-01-01

    and improve the limit of detections. Integration of pathogen capturing bio-receptors on microfluidic devices is a crucial step, which can facilitate recognition abilities in harsh chemical and physical conditions, offering a great commercial benefit to the food-manufacturing sector. This article reviews...... diagnosis competences. This has prompted researchers to call the current status of detection approaches into question and leverage new technologies for superior pathogen sensing outcomes. Novel strategies mainly rely on incorporating all the steps from sample preparation to detection in miniaturized devices...... recent advances in current state-of-the-art of sample preparation and concentration from food matrices with focus on bacterial capturing methods and sensing technologies, along with their advantages and limitations when integrated into microfluidic devices for online rapid detection of pathogens in foods...

  1. Detection and identification of concealed weapons using matrix pencil

    Science.gov (United States)

    Adve, Raviraj S.; Thayaparan, Thayananthan

    2011-06-01

    The detection and identification of concealed weapons is an extremely hard problem due to the weak signature of the target buried within the much stronger signal from the human body. This paper furthers the automatic detection and identification of concealed weapons by proposing the use of an effective approach to obtain the resonant frequencies in a measurement. The technique, based on Matrix Pencil, a scheme for model based parameter estimation also provides amplitude information, hence providing a level of confidence in the results. Of specific interest is the fact that Matrix Pencil is based on a singular value decomposition, making the scheme robust against noise.

  2. Biomolecular detection device

    Science.gov (United States)

    Huo, Qisheng [Albuquerque, NM; Liu, Jun [Albuquerque, NM

    2008-10-21

    A device for detecting and measuring the concentration of biomolecules in solution, utilizing a conducting electrode in contact with a solution containing target biomolecules, with a film with controllable pore size distribution characteristics applied to at least one surface of the conducting electrode. The film is functionalized with probe molecules that chemically interact with the target biomolecules at the film surface, blocking indicator molecules present in solution from diffusing from the solution to the electrode, thereby changing the electrochemical response of the electrode.

  3. Appearance detection device for fuel assembly

    International Nuclear Information System (INIS)

    Matsuoka, Toshihiro

    1998-01-01

    The prevent invention provides an appearance detection device which improves accuracy of images on a display and facilitates editing and selection of images upon detection of appearance of a reactor fuel assembly. Namely, the device of the present invention comprises (1) television cameras movable along fuel assemblies of a reactor, (2) a detection means for detecting the positions of the television cameras, (3) a convertor for converting analog image signals of the television cameras to digital image signals, (4) a memory means for sampling a predetermined portion of the images of the television camera and storing it together with the position signal obtained by the detection means and (5) a computer for selecting a plurality of images and positions from the above-mentioned means and joining them to one or a plurality of static images of the fuel assembly. At least two television cameras are disposed oppositely with each other. Then, position signals of the television cameras are designated by the stored sampling signals, and the fuel assembly at the position can be displayed quickly. It is scrolled, compressed or enlarged and formed into images. (I.S.)

  4. Multivariate algorithms for initiating event detection and identification in nuclear power plants

    International Nuclear Information System (INIS)

    Wu, Shun-Chi; Chen, Kuang-You; Lin, Ting-Han; Chou, Hwai-Pwu

    2018-01-01

    Highlights: •Multivariate algorithms for NPP initiating event detection and identification. •Recordings from multiple sensors are simultaneously considered for detection. •Both spatial and temporal information is used for event identification. •Untrained event isolation avoids falsely relating an untrained event. •Efficacy of the algorithms is verified with data from the Maanshan NPP simulator. -- Abstract: To prevent escalation of an initiating event into a severe accident, promptly detecting its occurrence and precisely identifying its type are essential. In this study, several multivariate algorithms for initiating event detection and identification are proposed to help maintain safe operations of nuclear power plants (NPPs). By monitoring changes in the NPP sensing variables, an event is detected when the preset thresholds are exceeded. Unlike existing approaches, recordings from sensors of the same type are simultaneously considered for detection, and no subjective reasoning is involved in setting these thresholds. To facilitate efficient event identification, a spatiotemporal feature extractor is proposed. The extracted features consist of the temporal traits used by existing techniques and the spatial signature of an event. Through an F-score-based feature ranking, only those that are most discriminant in classifying the events under consideration will be retained for identification. Moreover, an untrained event isolation scheme is introduced to avoid relating an untrained event to those in the event dataset so that improper recovery actions can be prevented. Results from experiments containing data of 12 event classes and a total of 125 events generated using a Taiwan’s Maanshan NPP simulator are provided to illustrate the efficacy of the proposed algorithms.

  5. Failed fuel detection device

    International Nuclear Information System (INIS)

    Kawai, Masayoshi; Hayashida, Yoshihisa; Niidome, Jiro.

    1985-01-01

    Purpose: To prevent intrusion of background neutrons to neutron detectors thereby improve the S/N ratio of the detectors in the failed fuel detection device of LMFBR type reactors. Constitution: Neutrons from the reactor core pass through the gaps around the penetration holes in which the primary pipeways pass through the concrete shielding walls and pass through the gaps between the thermal shielding members and the neutron moderating shielding members of the failed fuel detection device and then intrude into the neutron detectors. In view of the above, inner neutron moderating shielding members and movable or resilient neutron shielding members are disposed to the inside of the neutron moderating shielding member. Graphite or carbon hydrides such as paraffin or synthetic resin with a large neutron moderation effect are used as the outer moderating shielding member and materials such as boron or carbon are used for the inner members. As a result, the background neutrons are shielded by the inner neutron moderating shielding members and the resilient neutron shielding members, by which the S/N ratio of the neutron detectors can be increased to 2 - 4 times. (Moriyama, K.)

  6. Rapid identification and detection of pathogenic Fungi by padlock probes

    NARCIS (Netherlands)

    Tsui, C.K.M.; Wang, B.; Schoen, C.D.; Hamelin, R.C.

    2013-01-01

    Fungi are important pathogens of human diseases, as well as to agricultural crop and trees. Molecular diagnostics can detect diseases early, and improve identification accuracy and follow-up disease management. The use of padlock probe is effective to facilitate these detections and pathogen

  7. Design of temperature detection device for drum of belt conveyor

    Science.gov (United States)

    Zhang, Li; He, Rongjun

    2018-03-01

    For difficult wiring and big measuring error existed in the traditional temperature detection method for drum of belt conveyor, a temperature detection device for drum of belt conveyor based on Radio Frequency(RF) communication is designed. In the device, detection terminal can collect temperature data through tire pressure sensor chip SP370 which integrates temperature detection and RF emission. The receiving terminal which is composed of RF receiver chip and microcontroller receives the temperature data and sends it to Controller Area Network(CAN) bus. The test results show that the device meets requirements of field application with measuring error ±3.73 ° and single button battery can provide continuous current for the detection terminal over 1.5 years.

  8. Exploration of available feature detection and identification systems and their performance on radiographs

    Science.gov (United States)

    Wantuch, Andrew C.; Vita, Joshua A.; Jimenez, Edward S.; Bray, Iliana E.

    2016-10-01

    Despite object detection, recognition, and identification being very active areas of computer vision research, many of the available tools to aid in these processes are designed with only photographs in mind. Although some algorithms used specifically for feature detection and identification may not take explicit advantage of the colors available in the image, they still under-perform on radiographs, which are grayscale images. We are especially interested in the robustness of these algorithms, specifically their performance on a preexisting database of X-ray radiographs in compressed JPEG form, with multiple ways of describing pixel information. We will review various aspects of the performance of available feature detection and identification systems, including MATLABs Computer Vision toolbox, VLFeat, and OpenCV on our non-ideal database. In the process, we will explore possible reasons for the algorithms' lessened ability to detect and identify features from the X-ray radiographs.

  9. Identification of inorganic improvised explosive devices by analysis of postblast residues using portable capillary electrophoresis instrumentation and indirect photometric detection with a light-emitting diode.

    Science.gov (United States)

    Hutchinson, Joseph P; Evenhuis, Christopher J; Johns, Cameron; Kazarian, Artaches A; Breadmore, Michael C; Macka, Miroslav; Hilder, Emily F; Guijt, Rosanne M; Dicinoski, Greg W; Haddad, Paul R

    2007-09-15

    A commercial portable capillary electrophoresis (CE) instrument has been used to separate inorganic anions and cations found in postblast residues from improvised explosive devices (IEDs) of the type used frequently in terrorism attacks. The purpose of this analysis was to identify the type of explosive used. The CE instrument was modified for use with an in-house miniaturized light-emitting diode (LED) detector to enable sensitive indirect photometric detection to be employed for the detection of 15 anions (acetate, benzoate, carbonate, chlorate, chloride, chlorite, cyanate, fluoride, nitrate, nitrite, perchlorate, phosphate, sulfate, thiocyanate, thiosulfate) and 12 cations (ammonium, monomethylammonium, ethylammonium, potassium, sodium, barium, strontium, magnesium, manganese, calcium, zinc, lead) as the target analytes. These ions are known to be present in postblast residues from inorganic IEDs constructed from ammonium nitrate/fuel oil mixtures, black powder, and chlorate/perchlorate/sugar mixtures. For the analysis of cations, a blue LED (470 nm) was used in conjunction with the highly absorbing cationic dye, chrysoidine (absorption maximum at 453 nm). A nonaqueous background electrolyte comprising 10 mM chrysoidine in methanol was found to give greatly improved baseline stability in comparison to aqueous electrolytes due to the increased solubility of chrysoidine and its decreased adsorption onto the capillary wall. Glacial acetic acid (0.7% v/v) was added to ensure chrysoidine was protonated and to enhance separation selectivity by means of complexation with transition metal ions. The 12 target cations were separated in less than 9.5 min with detection limits of 0.11-2.30 mg/L (calculated at a signal-to-noise ratio of 3). The anions separation system utilized a UV LED (370 nm) in conjunction with an aqueous chromate electrolyte (absorption maximum at 371 nm) consisting of 10 mM chromium(VI) oxide and 10 mM sodium chromate, buffered with 40 mM tris

  10. Detection and response to unauthorized access to a communication device

    Science.gov (United States)

    Smith, Rhett; Gordon, Colin

    2015-09-08

    A communication gateway consistent with the present disclosure may detect unauthorized physical or electronic access and implement security actions in response thereto. A communication gateway may provide a communication path to an intelligent electronic device (IED) using an IED communications port configured to communicate with the IED. The communication gateway may include a physical intrusion detection port and a network port. The communication gateway may further include control logic configured to evaluate physical intrusion detection signal. The control logic may be configured to determine that the physical intrusion detection signal is indicative of an attempt to obtain unauthorized access to one of the communication gateway, the IED, and a device in communication with the gateway; and take a security action based upon the determination that the indication is indicative of the attempt to gain unauthorized access.

  11. Microfluidic devices for sample preparation and rapid detection of foodborne pathogens.

    Science.gov (United States)

    Kant, Krishna; Shahbazi, Mohammad-Ali; Dave, Vivek Priy; Ngo, Tien Anh; Chidambara, Vinayaka Aaydha; Than, Linh Quyen; Bang, Dang Duong; Wolff, Anders

    2018-03-10

    Rapid detection of foodborne pathogens at an early stage is imperative for preventing the outbreak of foodborne diseases, known as serious threats to human health. Conventional bacterial culturing methods for foodborne pathogen detection are time consuming, laborious, and with poor pathogen diagnosis competences. This has prompted researchers to call the current status of detection approaches into question and leverage new technologies for superior pathogen sensing outcomes. Novel strategies mainly rely on incorporating all the steps from sample preparation to detection in miniaturized devices for online monitoring of pathogens with high accuracy and sensitivity in a time-saving and cost effective manner. Lab on chip is a blooming area in diagnosis, which exploits different mechanical and biological techniques to detect very low concentrations of pathogens in food samples. This is achieved through streamlining the sample handling and concentrating procedures, which will subsequently reduce human errors and enhance the accuracy of the sensing methods. Integration of sample preparation techniques into these devices can effectively minimize the impact of complex food matrix on pathogen diagnosis and improve the limit of detections. Integration of pathogen capturing bio-receptors on microfluidic devices is a crucial step, which can facilitate recognition abilities in harsh chemical and physical conditions, offering a great commercial benefit to the food-manufacturing sector. This article reviews recent advances in current state-of-the-art of sample preparation and concentration from food matrices with focus on bacterial capturing methods and sensing technologies, along with their advantages and limitations when integrated into microfluidic devices for online rapid detection of pathogens in foods and food production line. Copyright © 2018. Published by Elsevier Inc.

  12. ARAPUCA a new device for liquid argon scintillation light detection

    International Nuclear Information System (INIS)

    Machado, A.A.; Segreto, E.

    2016-01-01

    We present a totally innovative device for the detection of liquid argon scintillation light, that has been named ARAPUCA (Argon R and D Advanced Program at UniCAmp). It is composed of a passive light collector and of active devices. The latters are standard SiPMs that operate at liquid argon temperature, while the passive collector is based on a new technology, never explored in this field before. It is a photon trap, that allows to collect light with extremely high efficiency. The total detection efficiency of the device can be tuned by modifying the ratio between the area of the active devices (SiPM) and the area of the optical window. For example, it will allow to reach a detection efficiency at the level of 1% on a surface of 50 × 50 cm 2 with an active coverage of 2 × 2 cm 2 (two/three large area SiPM). It is also a cheap device, since the major part of its cost is represented by the active devices. For these reason this appears to be the ideal device for scintillation light detection in large Time Projection Chambers. With appropriate modifications it can be used also in next generation Dark Matter detectors

  13. Prospective study of device-related complications in intensive care unit detected by virtual autopsy.

    Science.gov (United States)

    Wichmann, D; Heinemann, A; Zähler, S; Vogel, H; Höpker, W; Püschel, K; Kluge, S

    2018-06-01

    There has been increasing use of invasive techniques, such as extracorporeal organ support, in intensive care units (ICU), and declining autopsy rates. Thus, new measures are needed to maintain high-quality standards. We investigated the potential of computed tomography (CT)-based virtual autopsy to substitute for medical autopsy in this setting. We investigated the potential of virtual autopsy by post-mortem CT to identify complications associated with medical devices in a prospective study of patients who had died in the ICU. Clinical records were reviewed to determine the number and types of medical devices used, and findings from medical and virtual autopsies, related and unrelated to the medical devices, were compared. Medical and virtual autopsies could be performed in 61 patients (Group M/V), and virtual autopsy only in 101 patients (Group V). In Group M/V, 41 device-related complications and 30 device malpositions were identified, but only with a low inter-method agreement. Major findings unrelated to a device were identified in about 25% of patients with a high level of agreement between methods. In Group V, 8 device complications and 36 device malpositions were identified. Device-related complications are frequent in ICU patients. Virtual and medical autopsies showed clear differences in the detection of complications and device malpositions. Both methods should supplement each other rather than one alone for quality control of medical devices in the ICU. Further studies should focus on the identification of special patient populations in which virtual autopsy might be of particular benefit. NCT01541982. Copyright © 2018 British Journal of Anaesthesia. Published by Elsevier Ltd. All rights reserved.

  14. A Detection Device for the Signs of Human Life in Accident

    Science.gov (United States)

    Ning, Li; Ruilan, Zhang; Jian, Liu; Ruirui, Cheng; Yuhong, Diao

    2017-12-01

    A detection device for the signs of human life in accidents is a device used in emergency situations, such as the crash site. the scene of natural disasters, the battlefield ruins. it designed to detect the life signs of the distress under the injured ambulance vital signs devices. The device can on human vital signs, including pulse, respiration physiological signals to make rapid and accurate response. After some calculations, and after contrast to normal human physiological parameters given warning signals, in order for them to make timely ambulance judgment. In this case the device is required to do gymnastics convenience, ease of movement, power and detection of small flexible easy realization. This device has the maximum protection of the wounded safety significance.

  15. Synthetic mRNA devices that detect endogenous proteins and distinguish mammalian cells.

    Science.gov (United States)

    Kawasaki, Shunsuke; Fujita, Yoshihiko; Nagaike, Takashi; Tomita, Kozo; Saito, Hirohide

    2017-07-07

    Synthetic biology has great potential for future therapeutic applications including autonomous cell programming through the detection of protein signals and the production of desired outputs. Synthetic RNA devices are promising for this purpose. However, the number of available devices is limited due to the difficulty in the detection of endogenous proteins within a cell. Here, we show a strategy to construct synthetic mRNA devices that detect endogenous proteins in living cells, control translation and distinguish cell types. We engineered protein-binding aptamers that have increased stability in the secondary structures of their active conformation. The designed devices can efficiently respond to target proteins including human LIN28A and U1A proteins, while the original aptamers failed to do so. Moreover, mRNA delivery of an LIN28A-responsive device into human induced pluripotent stem cells (hiPSCs) revealed that we can distinguish living hiPSCs and differentiated cells by quantifying endogenous LIN28A protein expression level. Thus, our endogenous protein-driven RNA devices determine live-cell states and program mammalian cells based on intracellular protein information. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  16. Towards Flexibility Detection in Device-Level Energy Consumption

    DEFF Research Database (Denmark)

    Neupane, Bijay; Pedersen, Torben Bach; Thiesson, Bo

    2014-01-01

    The increasing drive towards green energy has boosted the installation of Renewable Energy Sources (RES). Increasing the share of RES in the power grid requires demand management by flexibility in the consumption. In this paper, we perform a state-of-the-art analysis on the flexibility and operat......The increasing drive towards green energy has boosted the installation of Renewable Energy Sources (RES). Increasing the share of RES in the power grid requires demand management by flexibility in the consumption. In this paper, we perform a state-of-the-art analysis on the flexibility...... and operation patterns of the devices in a set of real households. We propose a number of specific pre-processing steps such as operation stage segmentation, and aberrant operation duration removal to clean device level data. Further, we demonstrate various device operation properties such as hourly and daily...... regularities and patterns and the correlation between operating different devices. Subsequently, we show the existence of detectable time and energy flexibility in device operations. Finally, we provide various results providing a foundation for load- and flexibility-detection and -prediction at the device...

  17. Manufacturing and testing flexible microfluidic devices with optical and electrical detection mechanisms

    Science.gov (United States)

    Ivan, Marius G.; Vivet, Frédéric; Meinders, Erwin R.

    2010-06-01

    Flexible microfluidic devices made of poly(dimethylsiloxane) (PDMS) were manufactured by soft lithography, and tested in detection of ionic species using optical absorption spectroscopy and electrical measurements. PDMS was chosen due to its flexibility and ease of surface modification by exposure to plasma and UV treatment, its transparency in UV-Vis regions of the light spectrum, and biocompatibility. The dual-detection mechanism allows the user more freedom in choosing the detection tool, and a functional device was successfully tested. Optical lithography was employed for manufacturing templates, which were subsequently used for imprinting liquid PDMS by thermal curing. Gold electrodes having various widths and distances among them were patterned with optical lithography on the top part which sealed the microchannels, and the devices were employed for detection of ionic species in aqueous salt solutions as well as micro-electrolysis cells. Due to the transparency of PDMS in UV-Vis the microfluidics were also used as photoreactors, and the in-situ formed charged species were monitored by applying a voltage between electrodes. Upon addition of a colorimetric pH sensor, acid was detected with absorption spectroscopy.

  18. Active mems microbeam device for gas detection

    KAUST Repository

    Bouchaala, Adam M.

    2017-10-05

    Sensors and active switches for applications in gas detection and other fields are described. The devices are based on the softening and hardening nonlinear response behaviors of microelectromechanical systems (MEMS) clamped-clamped microbeams. In that context, embodiments of gas-triggered MEMS microbeam sensors and switches are described. The microbeam devices can be coated with a Metal-Organic Framework to achieve high sensitivity. For gas sensing, an amplitude-based tracking algorithm can be used to quantify an amount of gas captured by the devices according to frequency shift. Noise analysis is also conducted according to the embodiments, which shows that the microbeam devices have high stability against thermal noise. The microbeam devices are also suitable for the generation of binary sensing information for alarming, for example.

  19. Detection device for control rod scram

    International Nuclear Information System (INIS)

    Ishiyama, Satoshi.

    1989-01-01

    The device of the present invention comprises a control rod dropping separately from a control rod driving mechanism main body, a following tube falling separately accompanying therewith and a guide tube for guiding the dropping of the control rod and the following tube. Further, rare earth permanent magnets are embedded with the pole being axially oriented in the following tube and bobbins each mounted with an inner flange made of high magnetic permeability material are disposed to the guide tube. Coils are wound in the bobbin. In this control rod scram detection device, since magnetic fluxes can effectively be supplied to the coils, it is possible to obtain stable and highly reliable scram detection signals. Further, since the coils and the bobbins can be manufactured separately from the guide tube, their assemblies can be tested independently from the guide tube. (K.M.)

  20. Event storm detection and identification in communication systems

    International Nuclear Information System (INIS)

    Albaghdadi, Mouayad; Briley, Bruce; Evens, Martha

    2006-01-01

    Event storms are the manifestation of an important class of abnormal behaviors in communication systems. They occur when a large number of nodes throughout the system generate a set of events within a small period of time. It is essential for network management systems to detect every event storm and identify its cause, in order to prevent and repair potential system faults. This paper presents a set of techniques for the effective detection and identification of event storms in communication systems. First, we introduce a new algorithm to synchronize events to a single node in the system. Second, the system's event log is modeled as a normally distributed random process. This is achieved by using data analysis techniques to explore and then model the statistical behavior of the event log. Third, event storm detection is proposed using a simple test statistic combined with an exponential smoothing technique to overcome the non-stationary behavior of event logs. Fourth, the system is divided into non-overlapping regions to locate the main contributing regions of a storm. We show that this technique provides us with a method for event storm identification. Finally, experimental results from a commercially deployed multimedia communication system that uses these techniques demonstrate their effectiveness

  1. Leak detection device for control rod drive and detection method therefor

    International Nuclear Information System (INIS)

    Imasaki, Yoshio.

    1997-01-01

    The present invention provides a detection device for leak of cooling water from a sealed axial portion of control rod drives (CRD) disposed in a BWR type reactor and a monitoring method therefor. Namely, the CRD transfers rotation at the sealed axial portion and elevates/lowers a piston to insert/withdraw control rod into/from the reactor core. High pressure water is injected upon occurrence of scram to urge the piston upwardly thereby rapidly inserting the control rods. Leak detection pipelines are laid from the sealed axial portion. A flow glass is connected to the leak detection pipelines. Then, cooling water leaked from the sealed axial portion flows in the leak detection pipelines and flows into the flow glass. The flow rate of cooling water leaked from the sealed axial portion of the CRD can thus be detected by monitoring the flow glass. In addition, a flowmeter is connected to the leak detection pipelines, or the flowmeter and the flow glass are connected, and a flowmeter is connected downstream. Then, the flow rate of the leaked cooling water can be detected automatically. (I.S.)

  2. A Novel Biometric Identification Based on a User's Input Pattern Analysis for Intelligent Mobile Devices

    Directory of Open Access Journals (Sweden)

    Hojin Seo

    2012-07-01

    Full Text Available As intelligent mobile devices become more popular, security threats targeting them are increasing. The resource constraints of mobile devices, such as battery life and computing power, however, make it harder to handle such threats effectively. The existing physical and behavioural biometric identification methods - looked upon as good alternatives - are unsuitable for the current mobile environment. This paper proposes a specially designed biometric identification method for intelligent mobile devices by analysing the user's input patterns, such as a finger's touch duration, pressure level and the touching width of the finger on the touch screen. We collected the input pattern data of individuals to empirically test our method. Our testing results show that this method effectively identifies users with near a 100% rate of accuracy.

  3. DIRADTM - a system for real time detection and identification of radioactive objects

    International Nuclear Information System (INIS)

    Guillot, L.; Reboli, A.

    2009-01-01

    The authors present the DIRAD system (DIRAD stands for Detection and Identification of Radionuclides), an automatic system for real time identification of a radioactive anomaly and its interpretation in terms of risk level. It can be adapted to different contexts: pedestrian control, parcel or luggage control, road traffic control, and so on. In case of risk detection, an alert is transmitted in real time to a supervision station along with the whole set of spectral data

  4. Conjugate heat transfer analysis of an energy conversion device with an updated numerical model obtained through inverse identification

    International Nuclear Information System (INIS)

    Hey, Jonathan; Malloy, Adam C.; Martinez-Botas, Ricardo; Lamperth, Michael

    2015-01-01

    Highlights: • Conjugate heat transfer analysis of an electric machine. • Inverse identification method for estimating the model parameters. • Experimentally determined thermal properties and electromagnetic losses. • Coupling of inverse identification method with a numerical model. • Improved modeling accuracy through introduction of interface material. - Abstract: Energy conversion devices undergo thermal loading during their operation as a result of inefficiencies in the energy conversion process. This will eventually lead to degradation and possible failure of the device if the heat generated is not properly managed. The ability to accurately predict the thermal behavior of such a device during the initial developmental stage is an important requirement. However, accurate predictions of critical temperature is challenging due to the variation of heat transfer parameters from one device to another. The ability to determine the model parameters is key to accurately representing the heat transfer in such a device. This paper presents the use of an inverse identification technique to estimate the model parameters of an energy conversion device designed for vehicular applications. To simulate the imperfect contact and the presence of insulating materials in the permanent magnet electric machine, thin material are introduced at the component interface of the numerical model. The proposed inverse identification method is used to estimate the equivalent thermal conductance of the thin material. In addition, the electromagnetic losses generated in the permanent magnet is also derived indirectly from the temperature measurement using the same method. With the thermal properties and input parameters of the numerical model obtained from the inverse identification method, the critical temperature of the device can be predicted more accurately. The deviation between the maximum measured and predicted winding temperature is less than 2.4%

  5. Demonstration of the Robotic Gamma Locating and Isotopic Identification Device

    International Nuclear Information System (INIS)

    Anderson, M.O.; Conner, C.C.; Daniel, V.E.; McKay, M.D.; Yancey, N.A.

    2002-01-01

    The United States Department of Energy (DOE) continually seeks safer and more cost-effective technologies for use in decontaminating and decommissioning nuclear facilities. To this end, the Deactivation and Decommissioning Focus Area of DOE's Office of Science and Technology sponsors Large-Scale Demonstration and Deployment Projects (LSDDP) to test new technologies. As part of these projects, developers and vendors showcase new products designed to decrease health and safety risks to personnel and the environment, increase productivity, and lower costs. As part of the FY 2000 and 2001 LSDDP, the Idaho National Engineering and Environmental Laboratory (INEEL) collaborated with the Russian Research and Development Institute of Construction Technology (NIKIMT). This collaboration resulted in the development of the Robotic Gamma Locating and Isotopic Identification Device (RGL and IID) which integrated DOE Robotics Crosscutting (Rbx) technology with NIKIMT Russian gamma locating and isotopic identification technology. This paper will discuss the technologies involved in this integration and results from the demonstration including reduction of personnel exposure, increase in productivity, and reduced risk

  6. Development of a large-solid-angle and multi-device detection system for elemental analysis

    International Nuclear Information System (INIS)

    Satoh, T.; Ishii, K.; Kamiya, T.; Sakai, T.; Oikawa, M.; Arakawa, K.; Matsuyama, S.; Yamazaki, H.

    2003-01-01

    A new detection apparatus for both low energy X-rays like 1 keV and back scattered protons of MeV energy was developed. The detection apparatus consists of a large-solid-angle multi-device Si detector and a data acquisition system. The detector has 45 detection devices which are arranged in the shape of a pentagonal pyramid and fully cover a sample. A micro-beam irradiates the sample through the center of the pentagonal pyramid and X-rays emitted from the sample are detected in a solid angle of about 1.0 sr. This novel detection setup has about five times higher sensitivity than a conventional micro-PIXE camera. In addition, not only X-rays but back scattered protons can be detected, since the counting rate of back scattered protons per detection device is small despite lack of a passive absorber

  7. Analysis of Android Device-Based Solutions for Fall Detection

    Directory of Open Access Journals (Sweden)

    Eduardo Casilari

    2015-07-01

    Full Text Available Falls are a major cause of health and psychological problems as well as hospitalization costs among older adults. Thus, the investigation on automatic Fall Detection Systems (FDSs has received special attention from the research community during the last decade. In this area, the widespread popularity, decreasing price, computing capabilities, built-in sensors and multiplicity of wireless interfaces of Android-based devices (especially smartphones have fostered the adoption of this technology to deploy wearable and inexpensive architectures for fall detection. This paper presents a critical and thorough analysis of those existing fall detection systems that are based on Android devices. The review systematically classifies and compares the proposals of the literature taking into account different criteria such as the system architecture, the employed sensors, the detection algorithm or the response in case of a fall alarms. The study emphasizes the analysis of the evaluation methods that are employed to assess the effectiveness of the detection process. The review reveals the complete lack of a reference framework to validate and compare the proposals. In addition, the study also shows that most research works do not evaluate the actual applicability of the Android devices (with limited battery and computing resources to fall detection solutions.

  8. Analysis of Android Device-Based Solutions for Fall Detection.

    Science.gov (United States)

    Casilari, Eduardo; Luque, Rafael; Morón, María-José

    2015-07-23

    Falls are a major cause of health and psychological problems as well as hospitalization costs among older adults. Thus, the investigation on automatic Fall Detection Systems (FDSs) has received special attention from the research community during the last decade. In this area, the widespread popularity, decreasing price, computing capabilities, built-in sensors and multiplicity of wireless interfaces of Android-based devices (especially smartphones) have fostered the adoption of this technology to deploy wearable and inexpensive architectures for fall detection. This paper presents a critical and thorough analysis of those existing fall detection systems that are based on Android devices. The review systematically classifies and compares the proposals of the literature taking into account different criteria such as the system architecture, the employed sensors, the detection algorithm or the response in case of a fall alarms. The study emphasizes the analysis of the evaluation methods that are employed to assess the effectiveness of the detection process. The review reveals the complete lack of a reference framework to validate and compare the proposals. In addition, the study also shows that most research works do not evaluate the actual applicability of the Android devices (with limited battery and computing resources) to fall detection solutions.

  9. Analysis of Android Device-Based Solutions for Fall Detection

    Science.gov (United States)

    Casilari, Eduardo; Luque, Rafael; Morón, María-José

    2015-01-01

    Falls are a major cause of health and psychological problems as well as hospitalization costs among older adults. Thus, the investigation on automatic Fall Detection Systems (FDSs) has received special attention from the research community during the last decade. In this area, the widespread popularity, decreasing price, computing capabilities, built-in sensors and multiplicity of wireless interfaces of Android-based devices (especially smartphones) have fostered the adoption of this technology to deploy wearable and inexpensive architectures for fall detection. This paper presents a critical and thorough analysis of those existing fall detection systems that are based on Android devices. The review systematically classifies and compares the proposals of the literature taking into account different criteria such as the system architecture, the employed sensors, the detection algorithm or the response in case of a fall alarms. The study emphasizes the analysis of the evaluation methods that are employed to assess the effectiveness of the detection process. The review reveals the complete lack of a reference framework to validate and compare the proposals. In addition, the study also shows that most research works do not evaluate the actual applicability of the Android devices (with limited battery and computing resources) to fall detection solutions. PMID:26213928

  10. Near instrument-free, simple molecular device for rapid detection of herpes simplex viruses.

    Science.gov (United States)

    Lemieux, Bertrand; Li, Ying; Kong, Huimin; Tang, Yi-Wei

    2012-06-01

    The first near instrument-free, inexpensive and simple molecular diagnostic device (IsoAmp HSV, BioHelix Corp., MA, USA) recently received US FDA clearance for use in the detection of herpes simplex viruses (HSV) in genital and oral lesion specimens. The IsoAmp HSV assay uses isothermal helicase-dependent amplification in combination with a disposable, hermetically-sealed, vertical-flow strip identification. The IsoAmp HSV assay has a total test-to-result time of less than 1.5 h by omitting the time-consuming nucleic acid extraction. The diagnostic sensitivity and specificity are comparable to PCR and are superior to culture-based methods. The near instrument-free, rapid and simple characteristics of the IsoAmp HSV assay make it potentially suitable for point-of-care testing.

  11. Control rod position detection device

    International Nuclear Information System (INIS)

    Akita, Haruo; Ogiwara, Sakae.

    1996-01-01

    The device of the present invention is used in a back-up shut down system of an LMFBR type reactor which is easy for maintenance, has high reliability and can recognize the position of control rods accurately. Namely, a permanent magnet is disposed to a control rod extension tube connected to the lower portion of the control rod. The detector guide tube is disposed in the vicinity of the control rod extension tube. A detector having a detection coil is inserted into a detector tube. With such constitution, the control rod can be detected at one position using the following method. (1) the movement of the magnetic field of the permanent magnet is detected by the detection coil. (2) a plurality of grooves are formed on the control rod extension tube, and the movement of the grooves is detected. In addition, the detection coil is inserted into the detector guide tube, and the signals from the detection coil are inputted to a signal processing circuit disposed at the outside of the reactor vessel using an MI cable to enable the maintenance of the detector. Further, if the detector comprises a detection coil and an excitation coil, the position of a dropped control rod can be recognized at a plurality of points. (I.S.)

  12. A neural network device for on-line particle identification in cosmic ray experiments

    International Nuclear Information System (INIS)

    Scrimaglio, R.; Finetti, N.; D'Altorio, L.; Rantucci, E.; Raso, M.; Segreto, E.; Tassoni, A.; Cardarilli, G.C.

    2004-01-01

    On-line particle identification is one of the main goals of many experiments in space both for rare event studies and for optimizing measurements along the orbital trajectory. Neural networks can be a useful tool for signal processing and real time data analysis in such experiments. In this document we report on the performances of a programmable neural device which was developed in VLSI analog/digital technology. Neurons and synapses were accomplished by making use of Operational Transconductance Amplifier (OTA) structures. In this paper we report on the results of measurements performed in order to verify the agreement of the characteristic curves of each elementary cell with simulations and on the device performances obtained by implementing simple neural structures on the VLSI chip. A feed-forward neural network (Multi-Layer Perceptron, MLP) was implemented on the VLSI chip and trained to identify particles by processing the signals of two-dimensional position-sensitive Si detectors. The radiation monitoring device consisted of three double-sided silicon strip detectors. From the analysis of a set of simulated data it was found that the MLP implemented on the neural device gave results comparable with those obtained with the standard method of analysis confirming that the implemented neural network could be employed for real time particle identification

  13. Active mems microbeam device for gas detection

    KAUST Repository

    Bouchaala, Adam M.; Jaber, Nizar; Younis, Mohammad I.

    2017-01-01

    Sensors and active switches for applications in gas detection and other fields are described. The devices are based on the softening and hardening nonlinear response behaviors of microelectromechanical systems (MEMS) clamped-clamped microbeams

  14. A capacitive device approach to gravitational wave detection

    International Nuclear Information System (INIS)

    Mours, B.; Yvert, M.

    1988-05-01

    The possible use of a capacitive device to detect gravitational waves is discussed. Special emphasis is put on the detection of permanent periodic sources. The intrinsic properties of such a method, its sensitivity, directionality and its wide frequency band, makes it a very appealing one

  15. The DIRC counter: A new type of particle identification device for B factories

    International Nuclear Information System (INIS)

    Coyle, P.; Lu, A.

    1992-07-01

    A very thin, solid radiator, totally internally reflecting, imaging Cherenkov counter (DIRC) is described. this device is well matched to the hadronic charged particle identification requirements at an asymmetric e + e - B Factory

  16. The DIRC counter: A new type of particle identification device for B factories

    International Nuclear Information System (INIS)

    Ratcliff, B.

    1993-01-01

    A very thin, solid radiator, totally internally reflecting, imaging Cherenkov counter (DIRC) is described. This device is well matched to the hadronic charged particle identification requirements at an asymmetric e + e - B Factory

  17. Radiation detection device and a radiation detection method

    International Nuclear Information System (INIS)

    Blum, A.

    1975-01-01

    A radiation detection device is described including at least one scintillator in the path of radiation emissions from a distributed radiation source; a plurality of photodetectors for viewing each scintillator; a signal processing means, a storage means, and a data processing means that are interconnected with one another and connected to said photodetectors; and display means connected to the data processing means to locate a plurality of radiation sources in said distributed radiation source and to provide an image of the distributed radiation sources. The storage means includes radiation emission response data and location data from a plurality of known locations for use by the data processing means to derive a more accurate image by comparison of radiation responses from known locations with radiation responses from unknown locations. (auth)

  18. Approach for the Development of a Framework for the Identification of Activities of Daily Living Using Sensors in Mobile Devices

    Science.gov (United States)

    Pombo, Nuno

    2018-01-01

    Sensors available on mobile devices allow the automatic identification of Activities of Daily Living (ADL). This paper describes an approach for the creation of a framework for the identification of ADL, taking into account several concepts, including data acquisition, data processing, data fusion, and pattern recognition. These concepts can be mapped onto different modules of the framework. The proposed framework should perform the identification of ADL without Internet connection, performing these tasks locally on the mobile device, taking in account the hardware and software limitations of these devices. The main purpose of this paper is to present a new approach for the creation of a framework for the recognition of ADL, analyzing the allowed sensors available in the mobile devices, and the existing methods available in the literature. PMID:29466316

  19. Approach for the Development of a Framework for the Identification of Activities of Daily Living Using Sensors in Mobile Devices.

    Science.gov (United States)

    Pires, Ivan Miguel; Garcia, Nuno M; Pombo, Nuno; Flórez-Revuelta, Francisco; Spinsante, Susanna

    2018-02-21

    Sensors available on mobile devices allow the automatic identification of Activities of Daily Living (ADL). This paper describes an approach for the creation of a framework for the identification of ADL, taking into account several concepts, including data acquisition, data processing, data fusion, and pattern recognition. These concepts can be mapped onto different modules of the framework. The proposed framework should perform the identification of ADL without Internet connection, performing these tasks locally on the mobile device, taking in account the hardware and software limitations of these devices. The main purpose of this paper is to present a new approach for the creation of a framework for the recognition of ADL, analyzing the allowed sensors available in the mobile devices, and the existing methods available in the literature.

  20. Transmission environmental scanning electron microscope with scintillation gaseous detection device

    International Nuclear Information System (INIS)

    Danilatos, Gerasimos; Kollia, Mary; Dracopoulos, Vassileios

    2015-01-01

    A transmission environmental scanning electron microscope with use of a scintillation gaseous detection device has been implemented. This corresponds to a transmission scanning electron microscope but with addition of a gaseous environment acting both as environmental and detection medium. A commercial type of low vacuum machine has been employed together with appropriate modifications to the detection configuration. This involves controlled screening of various emitted signals in conjunction with a scintillation gaseous detection device already provided with the machine for regular surface imaging. Dark field and bright field imaging has been obtained along with other detection conditions. With a progressive series of modifications and tests, the theory and practice of a novel type of microscopy is briefly shown now ushering further significant improvements and developments in electron microscopy as a whole. - Highlights: • Novel scanning transmission electron microscopy (STEM) with an environmental scanning electron microscope (ESEM) called TESEM. • Use of the gaseous detection device (GDD) in scintillation mode that allows high resolution bright and dark field imaging in the TESEM. • Novel approach towards a unification of both vacuum and environmental conditions in both bulk/surface and transmission mode of electron microscopy

  1. An Instantaneous Low-Cost Point-of-Care Anemia Detection Device

    Directory of Open Access Journals (Sweden)

    Jaime Punter-Villagrasa

    2015-02-01

    Full Text Available We present a small, compact and portable device for point-of-care instantaneous early detection of anemia. The method used is based on direct hematocrit measurement from whole blood samples by means of impedance analysis. This device consists of a custom electronic instrumentation and a plug-and-play disposable sensor. The designed electronics rely on straightforward standards for low power consumption, resulting in a robust and low consumption device making it completely mobile with a long battery life. Another approach could be powering the system based on other solutions like indoor solar cells, or applying energy-harvesting solutions in order to remove the batteries. The sensing system is based on a disposable low-cost label-free three gold electrode commercial sensor for 50 µL blood samples. The device capability for anemia detection has been validated through 24 blood samples, obtained from four hospitalized patients at Hospital Clínic. As a result, the response, effectiveness and robustness of the portable point-of-care device to detect anemia has been proved with an accuracy error of 2.83% and a mean coefficient of variation of 2.57% without any particular case above 5%.

  2. A new algorithmic approach for fingers detection and identification

    Science.gov (United States)

    Mubashar Khan, Arslan; Umar, Waqas; Choudhary, Taimoor; Hussain, Fawad; Haroon Yousaf, Muhammad

    2013-03-01

    Gesture recognition is concerned with the goal of interpreting human gestures through mathematical algorithms. Gestures can originate from any bodily motion or state but commonly originate from the face or hand. Hand gesture detection in a real time environment, where the time and memory are important issues, is a critical operation. Hand gesture recognition largely depends on the accurate detection of the fingers. This paper presents a new algorithmic approach to detect and identify fingers of human hand. The proposed algorithm does not depend upon the prior knowledge of the scene. It detects the active fingers and Metacarpophalangeal (MCP) of the inactive fingers from an already detected hand. Dynamic thresholding technique and connected component labeling scheme are employed for background elimination and hand detection respectively. Algorithm proposed a new approach for finger identification in real time environment keeping the memory and time constraint as low as possible.

  3. Carbon nanotubes for gas detection: materials preparation and device assembly

    International Nuclear Information System (INIS)

    Terranova, M L; Lucci, M; Orlanducci, S; Tamburri, E; Sessa, V; Reale, A; Carlo, A Di

    2007-01-01

    An efficient sensing device for NH 3 and NO x detection has been realized using ordered arrays of single-walled C nanotubes deposited onto an interdigitated electrode platform operating at room temperature. The sensing material has been prepared using several chemical-physical techniques for purification and positioning of the nanotubes inside the electrode gaps. In particular, both DC and AC fields have been applied in order to move and to align the nanostructures by electrophoresis and dielectrophoresis processes. We investigated the effects of different voltages applied to a gate contact on the back side of the substrate on the performances of the device and found that for different gas species (NH 3 , NO x ) a constant gate bias increases the sensitivity for gas detection. Moreover, in this paper we demonstrate that a pulsed bias applied to the gate contact facilitates the gas interaction with the nanotubes, either reducing the absorption times or accelerating the desorption times, thus providing a fast acceleration and a dramatic improvement of the time dependent behaviour of the device

  4. Experimental Measurement-Device-Independent Entanglement Detection

    Science.gov (United States)

    Nawareg, Mohamed; Muhammad, Sadiq; Amselem, Elias; Bourennane, Mohamed

    2015-02-01

    Entanglement is one of the most puzzling features of quantum theory and of great importance for the new field of quantum information. The determination whether a given state is entangled or not is one of the most challenging open problems of the field. Here we report on the experimental demonstration of measurement-device-independent (MDI) entanglement detection using witness method for general two qubits photon polarization systems. In the MDI settings, there is no requirement to assume perfect implementations or neither to trust the measurement devices. This experimental demonstration can be generalized for the investigation of properties of quantum systems and for the realization of cryptography and communication protocols.

  5. Direct Detection and Imaging of Low-Energy Electrons with Delta-Doped Charge-Coupled Devices

    Science.gov (United States)

    Nikzad, S.; Yu, Q.; Smith, A. L.; Jones, T. J.; Tombrello, T. A.; Elliott, S. T.

    1998-01-01

    We report the use fo delta-doped charge-coupled devices (CCDs) for direct detection of electrons in the 50-1500 eV energy range. These are the first measurements with a solid state device to detect electrons in this energy range.

  6. SmartMal: a service-oriented behavioral malware detection framework for mobile devices.

    Science.gov (United States)

    Wang, Chao; Wu, Zhizhong; Li, Xi; Zhou, Xuehai; Wang, Aili; Hung, Patrick C K

    2014-01-01

    This paper presents SmartMal--a novel service-oriented behavioral malware detection framework for vehicular and mobile devices. The highlight of SmartMal is to introduce service-oriented architecture (SOA) concepts and behavior analysis into the malware detection paradigms. The proposed framework relies on client-server architecture, the client continuously extracts various features and transfers them to the server, and the server's main task is to detect anomalies using state-of-art detection algorithms. Multiple distributed servers simultaneously analyze the feature vector using various detectors and information fusion is used to concatenate the results of detectors. We also propose a cycle-based statistical approach for mobile device anomaly detection. We accomplish this by analyzing the users' regular usage patterns. Empirical results suggest that the proposed framework and novel anomaly detection algorithm are highly effective in detecting malware on Android devices.

  7. An experimental study of UWB device-free person detection and ranging

    NARCIS (Netherlands)

    Kilic, Y.; Wymeersch, Henk; Meijerink, Arjan; Bentum, Marinus Jan; Scanlon, W.G.

    2013-01-01

    Passive person detection and localization is an emerging area in UWB localization systems, whereby people are not required to carry any UWB ranging device. Based on experimental data, we propose a novel method to detect static persons in the absence of template waveforms, and to compute distances to

  8. Device for acoustic detection in a nuclear reactor

    International Nuclear Information System (INIS)

    Hanff, M.; Lions, N.; Peronnet, J.

    1975-01-01

    A description is given of a device which comprises a first acoustic conductor placed vertically within the coolant liquid contained in a nuclear reactor vessel and a second coaxial acoustic conductor extending to the exterior of the reactor vessel. The device essentially comprises an accelerometer assembly for detecting signals delivered by the second conductor and an amplifier which applies the detected signals to measuring instruments located outside the reactor vessel. The accelerometer comprises an amplifying pressure needle carried by the upper end of the second conductor, a piezoelectric ceramic element, a block fitted with a spring for applying the ceramic element against the needle and a preamplifier connected in series with the amplifier

  9. Scintillation device of X-ray detection

    International Nuclear Information System (INIS)

    Polack, F.; Bigler, E.

    1985-01-01

    The detection device comprises a screen made of microtubes transparent to the light emitted by a scintillator material in the microtube channels. The scintillator material optical index is greater than the microtube material index, so as to constitute optical fiber, with index rise, guiding the light toward the outside [fr

  10. Multistage audiovisual integration of speech: dissociating identification and detection

    DEFF Research Database (Denmark)

    Eskelund, Kasper; Tuomainen, Jyrki; Andersen, Tobias

    2011-01-01

    Speech perception integrates auditory and visual information. This is evidenced by the McGurk illusion where seeing the talking face influences the auditory phonetic percept and by the audiovisual detection advantage where seeing the talking face influences the detectability of the acoustic speech...... signal. Here we show that identification of phonetic content and detection can be dissociated as speech-specific and non-specific audiovisual integration effects. To this end, we employed synthetically modified stimuli, sine wave speech (SWS), which is an impoverished speech signal that only observers...... informed of its speech-like nature recognize as speech. While the McGurk illusion only occurred for informed observers the audiovisual detection advantage occurred for naïve observers as well. This finding supports a multi-stage account of audiovisual integration of speech in which the many attributes...

  11. Target Detection, Identification, and Marksmanship Under Various Types of Physiological Strain

    National Research Council Canada - National Science Library

    Tikuisis, Peter

    2006-01-01

    .... Using a small arms trainer (SAT), target detection, identification, and engagement were tested under a variety of conditions including heat and cold exposure, fatiguing exercise, and sleep deprivation, with caffeine intervention...

  12. SmartMal: A Service-Oriented Behavioral Malware Detection Framework for Mobile Devices

    Directory of Open Access Journals (Sweden)

    Chao Wang

    2014-01-01

    Full Text Available This paper presents SmartMal—a novel service-oriented behavioral malware detection framework for vehicular and mobile devices. The highlight of SmartMal is to introduce service-oriented architecture (SOA concepts and behavior analysis into the malware detection paradigms. The proposed framework relies on client-server architecture, the client continuously extracts various features and transfers them to the server, and the server’s main task is to detect anomalies using state-of-art detection algorithms. Multiple distributed servers simultaneously analyze the feature vector using various detectors and information fusion is used to concatenate the results of detectors. We also propose a cycle-based statistical approach for mobile device anomaly detection. We accomplish this by analyzing the users’ regular usage patterns. Empirical results suggest that the proposed framework and novel anomaly detection algorithm are highly effective in detecting malware on Android devices.

  13. Effect of Various Environmental Stressors on Target Detection, Identification, and Marksmanship

    National Research Council Canada - National Science Library

    Tikuisis, Peter; Keefe, Allan A

    2007-01-01

    .... Using a small arms trainer (SAT), the detection, identification, and engagement of targets were tested under a variety of environmentally stressful conditions including heat and cold exposure, noise, fatiguing exercise, and sleep...

  14. Bio-sample detection on paper-based devices with inkjet printer-sprayed reagents.

    Science.gov (United States)

    Liang, Wun-Hong; Chu, Chien-Hung; Yang, Ruey-Jen

    2015-12-01

    The reagent required for bio-sample detection on paper-based analytical devices is generally introduced manually using a pipette. Such an approach is time-consuming; particularly if a large number of devices are required. Automated methods provide a far more convenient solution for large-scale production, but incur a substantial cost. Accordingly, the present study proposes a low-cost method for the paper-based analytical devices in which the biochemical reagents are sprayed onto the device directly using a modified commercial inkjet printer. The feasibility of the proposed method is demonstrated by performing aspartate aminotransferase (AST) and alanine aminotransferase (ALT) tests using simple two-dimensional (2D) paper-based devices. In both cases, the reaction process is analyzed using an image-processing-based colorimetric method. The experimental results show that for AST detection within the 0-105 U/l concentration range, the optimal observation time is around four minutes, while for ALT detection in the 0-125 U/l concentration range, the optimal observation time is approximately one minute. Finally, for both samples, the detection performance of the sprayed-reagent analytical devices is insensitive to the glucose concentration. Copyright © 2015 Elsevier B.V. All rights reserved.

  15. Transient photoconductive gain in a-Si:H devices and its applications in radiation detection

    International Nuclear Information System (INIS)

    Lee, H.K.; Suh, T.S.; Choe, B.Y.; Shinn, K.S.; Perez-Mendez, V.

    1997-01-01

    Using the transient behavior of the photoconductive-gain mechanism, a signal gain in radiation detection with a-Si:H devices may be possible. The photoconductive gain mechanism in two types of hydrogenated amorphous silicon devices, p-i-n and n-i-n configurations, was investigated in connection with applications to radiation detection. Photoconductive gain was measured in two time scales: one for short pulses of visible light ( 2 . Various gain results are discussed in terms of the device structure, applied bias and dark-current density. (orig.)

  16. An experimental method for detecting blood splatter from retractable phlebotomy and intravascular devices.

    Science.gov (United States)

    Haiduven, Donna; Applegarth, Shawn; Shroff, Miloni

    2009-03-01

    This study was designed to evaluate the safety of retractable intravascular devices in terms of their potential to produce blood splatter. A method for measuring this blood splatter designed by the research team was used to evaluate 3 specific intravascular devices. Scientific filters were positioned around the retraction mechanisms of the devices and weighed with an analytical scale, both before and after activation, in a simulated vein containing mock venous blood. The difference in filter mass was used as the primary unit of analysis to detect blood splatter. In addition, the filters were visually inspected for the presence or absence of blood. A paired t-test revealed significant differences in the prefilter and postfilter groups for 2 of the 3 devices tested (P blood was detected on 23% to 40% of the scientific filters for 2 of the devices. Our findings indicate a potential for bloodborne pathogen exposure with the use of intravascular devices with a retractable mechanism. This experiment may serve as a model in the design and implementation of future sharps device evaluation protocols to validate the threat of bloodborne pathogen exposure.

  17. Automatic cell identification and visualization using digital holographic microscopy with head mounted augmented reality devices.

    Science.gov (United States)

    O'Connor, Timothy; Rawat, Siddharth; Markman, Adam; Javidi, Bahram

    2018-03-01

    We propose a compact imaging system that integrates an augmented reality head mounted device with digital holographic microscopy for automated cell identification and visualization. A shearing interferometer is used to produce holograms of biological cells, which are recorded using customized smart glasses containing an external camera. After image acquisition, segmentation is performed to isolate regions of interest containing biological cells in the field-of-view, followed by digital reconstruction of the cells, which is used to generate a three-dimensional (3D) pseudocolor optical path length profile. Morphological features are extracted from the cell's optical path length map, including mean optical path length, coefficient of variation, optical volume, projected area, projected area to optical volume ratio, cell skewness, and cell kurtosis. Classification is performed using the random forest classifier, support vector machines, and K-nearest neighbor, and the results are compared. Finally, the augmented reality device displays the cell's pseudocolor 3D rendering of its optical path length profile, extracted features, and the identified cell's type or class. The proposed system could allow a healthcare worker to quickly visualize cells using augmented reality smart glasses and extract the relevant information for rapid diagnosis. To the best of our knowledge, this is the first report on the integration of digital holographic microscopy with augmented reality devices for automated cell identification and visualization.

  18. Detection and Identification of People at a Critical Infrastructure Facilities of Trafic Buildings

    Directory of Open Access Journals (Sweden)

    Rastislav PIRNÍK

    2014-12-01

    Full Text Available This paper focuses on identification of persons entering objects of crucial infrastructure and subsequent detection of movement in parts of objects. It explains some of the technologies and approaches to processing specific image information within existing building apparatus. The article describes the proposed algorithm for detection of persons. It brings a fresh approach to detection of moving objects (groups of persons involved in enclosed areas focusing on securing freely accessible places in buildings. Based on the designed algorithm of identification with presupposed utilisation of 3D application, motion trajectory of persons in delimited space can be automatically identified. The application was created in opensource software tool using the OpenCV library.

  19. Detection and identification of Staphylococcus aureus in raw milk by ...

    African Journals Online (AJOL)

    STORAGESEVER

    2010-04-12

    Apr 12, 2010 ... detection and identification of S. aureus in raw milk demonstrated high sensitivity and specificity. Key words: Microarray .... sterile after screening for S. aureus contamination according to the procedure described by Wang ... methods, the microarray method is high throughput, specific, and sensitive and also ...

  20. Transmission environmental scanning electron microscope with scintillation gaseous detection device.

    Science.gov (United States)

    Danilatos, Gerasimos; Kollia, Mary; Dracopoulos, Vassileios

    2015-03-01

    A transmission environmental scanning electron microscope with use of a scintillation gaseous detection device has been implemented. This corresponds to a transmission scanning electron microscope but with addition of a gaseous environment acting both as environmental and detection medium. A commercial type of low vacuum machine has been employed together with appropriate modifications to the detection configuration. This involves controlled screening of various emitted signals in conjunction with a scintillation gaseous detection device already provided with the machine for regular surface imaging. Dark field and bright field imaging has been obtained along with other detection conditions. With a progressive series of modifications and tests, the theory and practice of a novel type of microscopy is briefly shown now ushering further significant improvements and developments in electron microscopy as a whole. Copyright © 2014 Elsevier B.V. All rights reserved.

  1. Manufacturing and testing flexible microfluidic devices with optical and electrical detection mechanisms

    OpenAIRE

    Ivan, M.G.; Vivet, F.; Meinders, E.R.

    2010-01-01

    Flexible microfluidic devices made of poly(dimethylsiloxane) (PDMS) were manufactured by soft lithography, and tested in detection of ionic species using optical absorption spectroscopy and electrical measurements. PDMS was chosen due to its flexibility and ease of surface modification by exposure to plasma and UV treatment, its transparency in UV-Vis regions of the light spectrum, and biocompatibility. The dual-detection mechanism allows the user more freedom in choosing the detection tool, ...

  2. Real-time change detection for countering improvised explosive devices

    NARCIS (Netherlands)

    Wouw, van de D.W.J.M.; Rens, van K.; Lint, van R.H.; Jaspers, Egbert; With, de P.H.N.; Loce, R.P.; Saber, E.

    2014-01-01

    We explore an automatic real-time change detection system to assist military personnel during transport and surveillance, by detection changes in the environment with respect to a previous operation. Such changes may indicate the presence of Improvised Explosive Devices (IEDs), which can then be

  3. A device for identification of respective images in orthogonal localization roentgenograms

    International Nuclear Information System (INIS)

    Ganchev, M.

    1977-01-01

    Some problems which might be solved with the device, originally intended for localization of implanted radioactive wires, include: conjugation check-up of orthogonal localization roentgenograms; localization of partially screened radioactive sources in the patient body; localization of Fletcher's trapezium points in the pelvis; identification of the respective images of contrast filled lymph nodes and localization of some bone hallmarks, visible only on one of two localization roentgenograms. (author)

  4. Feasibility of Trace Alcohol Congener Detection and Identification Using Laser-Induced Breakdown Spectroscopy

    International Nuclear Information System (INIS)

    Zhang Jialiang; Wang Shangmin; Zhao Lixian; Liu Liying; Wang Dezhen

    2014-01-01

    In this paper, a feasible scheme is reported for the detection and identification of trace alcohol congeners that have identical elemental composition using laser-induced breakdown spectroscopy (LIBS). In the scheme, an intensive pulsed laser is used to break down trace alcohol samples and the optical emission spectra of the induced plasma are collected for the detection and identification of alcohol molecules. In order to prepare trace alcohol samples, pure ethanol or methanol is bubbled by argon carrier gas and then mixed into matrix gases. The key issue for the scheme is to constitute indices from the LIBS data of the alcohol samples. Two indices are found to be suitable for alcohol detection and identification. One is the emission intensity ratio (denoted as H/C) of the hydrogen line (653.3 nm) to the carbon line (247.9 nm) for identification and the other is the ratio of the carbon line (as C/Ar) or the hydrogen line (as H/Ar) to the argon lines (866.7 nm) for quantitative detection. The calibration experiment result shows that the index H/C is specific for alcohol congeners while almost being independent of alcohol concentration. In detail, the H/C keeps a specific constant of 34 and 23 respectively for ethanol and methanol. In the meanwhile, the C/Ar and H/Ar indices respond almost linearly to the alcohol concentration below 1300 ppm, and are therefore competent for concentration measurement. With the indices, trace alcohol concentration measurement achieves a limit of 140 ppm using a laser pulse energy of 300 mJ. (plasma technology)

  5. Heart Rate Detection Using Microsoft Kinect: Validation and Comparison to Wearable Devices.

    Science.gov (United States)

    Gambi, Ennio; Agostinelli, Angela; Belli, Alberto; Burattini, Laura; Cippitelli, Enea; Fioretti, Sandro; Pierleoni, Paola; Ricciuti, Manola; Sbrollini, Agnese; Spinsante, Susanna

    2017-08-02

    Contactless detection is one of the new frontiers of technological innovation in the field of healthcare, enabling unobtrusive measurements of biomedical parameters. Compared to conventional methods for Heart Rate (HR) detection that employ expensive and/or uncomfortable devices, such as the Electrocardiograph (ECG) or pulse oximeter, contactless HR detection offers fast and continuous monitoring of heart activities and provides support for clinical analysis without the need for the user to wear a device. This paper presents a validation study for a contactless HR estimation method exploiting RGB (Red, Green, Blue) data from a Microsoft Kinect v2 device. This method, based on Eulerian Video Magnification (EVM), Photoplethysmography (PPG) and Videoplethysmography (VPG), can achieve performance comparable to classical approaches exploiting wearable systems, under specific test conditions. The output given by a Holter, which represents the gold-standard device used in the test for ECG extraction, is considered as the ground-truth, while a comparison with a commercial smartwatch is also included. The validation process is conducted with two modalities that differ for the availability of a priori knowledge about the subjects' normal HR. The two test modalities provide different results. In particular, the HR estimation differs from the ground-truth by 2% when the knowledge about the subject's lifestyle and his/her HR is considered and by 3.4% if no information about the person is taken into account.

  6. Mass and charge identification of fragments detected with the Chimera Silicon-CsI(Tl) telescopes

    Energy Technology Data Exchange (ETDEWEB)

    Le Neindre, N.; Alderighi, M.; Anzalone, A.; Barna, R.; Bartolucci, M.; Berceanu, I.; Borderie, B.; Bougault, R.; Bruno, M.; Cardella, G.; Cavallaro, S.; D' Agostino, M. E-mail: dagostino@bo.infn.it; Dayras, R.; De Filippo, E.; De Pasquale, D.; Geraci, E.; Giustolisi, F.; Grzeszczuk, A.; Guazzoni, P.; Guinet, D.; Iacono-Manno, M.; Italiano, A.; Kowalski, S.; Lanchais, A.; Lanzano, G.; Lanzalone, G.; Li, S.; Lo Nigro, S.; Maiolino, C.; Manfredi, G.; Moisa, D.; Pagano, A.; Papa, M.; Paduszynski, T.; Petrovici, M.; Piasecki, E.; Pirrone, S.; Politi, G.; Pop, A.; Porto, F.; Rivet, M.F.; Rosato, E.; Russo, S.; Sambataro, S.; Sechi, G.; Simion, V.; Sperduto, M.L.; Steckmeyer, J.C.; Sutera, C.; Trifiro, A.; Tassan-Got, L.; Trimarchi, M.; Vannini, G.; Vigilante, M.; Wilczynski, J.; Wu, H.; Xiao, Z.; Zetta, L.; Zipper, W

    2002-09-01

    Mass and charge identification of charged products detected with Silicon-CsI(Tl) telescopes of the Chimera apparatus are presented. An identification function, based on the Bethe-Bloch formula, is used to fit empirical correlations between {delta}E and E ADC readings, in order to determine, event by event, the atomic and mass numbers of the detected charged reaction products prior to energy calibration.

  7. Development of a PMMA Electrochemical Microfluidic Device for Carcinoembryonic Antigen Detection

    Science.gov (United States)

    Van Anh, Nguyen; Van Trung, Hoang; Tien, Bui Quang; Binh, Nguyen Hai; Ha, Cao Hong; Le Huy, Nguyen; Loc, Nguyen Thai; Thu, Vu Thi; Lam, Tran Dai

    2016-05-01

    In this study, a poly(methyl methacrylate) (PMMA) microfluidic device fabricated by an inexpensive CO2 laser etching system was developed for detection of carcino-embryonic antigens (CEA). The device was capable of working in continuous mode and was designed with the aid of numerical simulation. The detection of target CEA was based on immuno-assay via magnetic particles and electrochemical sensing. The as-prepared microfluidic can be used to detect CEA at the relatively low concentration of 150 pg mL-1. The device could be reused many times, since the capture and removal of magnetic particles in the assay could be manipulated by an external magnetic field. The proposed approach appears to be suitable for high-throughput and automated analysis of large biomolecules such as tumor markers and pathogens.

  8. Multistage audiovisual integration of speech: dissociating identification and detection.

    Science.gov (United States)

    Eskelund, Kasper; Tuomainen, Jyrki; Andersen, Tobias S

    2011-02-01

    Speech perception integrates auditory and visual information. This is evidenced by the McGurk illusion where seeing the talking face influences the auditory phonetic percept and by the audiovisual detection advantage where seeing the talking face influences the detectability of the acoustic speech signal. Here, we show that identification of phonetic content and detection can be dissociated as speech-specific and non-specific audiovisual integration effects. To this end, we employed synthetically modified stimuli, sine wave speech (SWS), which is an impoverished speech signal that only observers informed of its speech-like nature recognize as speech. While the McGurk illusion only occurred for informed observers, the audiovisual detection advantage occurred for naïve observers as well. This finding supports a multistage account of audiovisual integration of speech in which the many attributes of the audiovisual speech signal are integrated by separate integration processes.

  9. Detection and Identification of Arcobacter species in Poultry in Assiut Governorate, Upper Egypt

    Directory of Open Access Journals (Sweden)

    Ahmed K. Hassan

    2017-04-01

    Full Text Available This work aimed to detect, identify and study the epidemiology of Arcobacter species in avian species in Upper Egypt. A total 600 samples, including cloacal swabs and intestinal samples were collected from chickens, turkeys and ducks in Assiut Governorate in Upper Egypt. Using conventional phenotypic methods for isolation and identification, Arcobacter species could be isolated and identified with percentage 25.5% in chickens, 9.5% in turkeys and 14% in ducks. Sixteen randomly selected phenotypically identified Arcobacter species isolates were confirmed using one step multiplex PCR assay. In conclusion, Arcobacter species could be detected and identified from various avian species with variable incidence. Conventional phenotypic methods for detection and differentiation of Arcobacter species are often hampered by many limitations, while molecular methods, and PCR, in particular can provide a sensitive and rapid alternative method for detection and identification of Arcobacter species in different domestic poultry species.

  10. One simple DNA extraction device and its combination with modified visual loop-mediated isothermal amplification for rapid on-field detection of genetically modified organisms.

    Science.gov (United States)

    Zhang, Miao; Liu, Yinan; Chen, Lili; Quan, Sheng; Jiang, Shimeng; Zhang, Dabing; Yang, Litao

    2013-01-02

    Quickness, simplicity, and effectiveness are the three major criteria for establishing a good molecular diagnosis method in many fields. Herein we report a novel detection system for genetically modified organisms (GMOs), which can be utilized to perform both on-field quick screening and routine laboratory diagnosis. In this system, a newly designed inexpensive DNA extraction device was used in combination with a modified visual loop-mediated isothermal amplification (vLAMP) assay. The main parts of the DNA extraction device included a silica gel membrane filtration column and a modified syringe. The DNA extraction device could be easily operated without using other laboratory instruments, making it applicable to an on-field GMO test. High-quality genomic DNA (gDNA) suitable for polymerase chain reaction (PCR) and isothermal amplification could be quickly isolated from plant tissues using this device within 15 min. In the modified vLAMP assay, a microcrystalline wax encapsulated detection bead containing SYBR green fluorescent dye was introduced to avoid dye inhibition and cross-contaminations from post-LAMP operation. The system was successfully applied and validated in screening and identification of GM rice, soybean, and maize samples collected from both field testing and the Grain Inspection, Packers, and Stockyards Administration (GIPSA) proficiency test program, which demonstrated that it was well-adapted to both on-field testing and/or routine laboratory analysis of GMOs.

  11. Medical devices; immunology and microbiology devices; classification of nucleic acid-based devices for the detection of Mycobacterium tuberculosis complex and the genetic mutations associated with antibiotic resistance. Final order.

    Science.gov (United States)

    2014-10-22

    The Food and Drug Administration (FDA) is classifying nucleic acid-based in vitro diagnostic devices for the detection of Mycobacterium tuberculosis complex (MTB-complex) and the genetic mutations associated with MTB-complex antibiotic resistance in respiratory specimens devices into class II (special controls). The Agency is classifying the device into class II (special controls) because special controls, in addition to general controls, will provide a reasonable assurance of safety and effectiveness of the device.

  12. Immunity-based detection, identification, and evaluation of aircraft sub-system failures

    Science.gov (United States)

    Moncayo, Hever Y.

    This thesis describes the design, development, and flight-simulation testing of an integrated Artificial Immune System (AIS) for detection, identification, and evaluation of a wide variety of sensor, actuator, propulsion, and structural failures/damages including the prediction of the achievable states and other limitations on performance and handling qualities. The AIS scheme achieves high detection rate and low number of false alarms for all the failure categories considered. Data collected using a motion-based flight simulator are used to define the self for an extended sub-region of the flight envelope. The NASA IFCS F-15 research aircraft model is used and represents a supersonic fighter which include model following adaptive control laws based on non-linear dynamic inversion and artificial neural network augmentation. The flight simulation tests are designed to analyze and demonstrate the performance of the immunity-based aircraft failure detection, identification and evaluation (FDIE) scheme. A general robustness analysis is also presented by determining the achievable limits for a desired performance in the presence of atmospheric perturbations. For the purpose of this work, the integrated AIS scheme is implemented based on three main components. The first component performs the detection when one of the considered failures is present in the system. The second component consists in the identification of the failure category and the classification according to the failed element. During the third phase a general evaluation of the failure is performed with the estimation of the magnitude/severity of the failure and the prediction of its effect on reducing the flight envelope of the aircraft system. Solutions and alternatives to specific design issues of the AIS scheme, such as data clustering and empty space optimization, data fusion and duplication removal, definition of features, dimensionality reduction, and selection of cluster/detector shape are also

  13. Remote device to detect the neutrons and gamma-ray activity

    International Nuclear Information System (INIS)

    Ermakov, G.; Korolev, M.; Lopatin, Yu.; Rtishchev, A.

    1999-01-01

    The device for monitoring of gamma activity and neutrons with the following advantages was successfully developed and manufactured: extremely low power consumption which allow the long time of monitoring (up to one year or even more for GM device); high level of the intellect (build in processor); a big memory to remember results (512 Kb) including the date of events (min, hour, day, month, year); extremely simple and highly automated mode of operating; infrared interface to pass information to the external computer; high level of the IP protection; wide range of possible application. The devices could be used as follows: detection of unauthorized movement (removal) of the nuclear material and/or radioactive sources from the facility, monitoring of the radioactivity for different purposes in places with harsh climatic conditions [ru

  14. Detection of multiple tumor markers using ultra-long carbon nanotube devices

    Science.gov (United States)

    So, Hye-Mi; Park, Dong-Won; Kim, Beom Soo; Kong, Ki-Jeong; Buh, Gyoung-Ho; Chang, Hyunju; Lee, Jeong-O.; Kong, Jing

    2008-03-01

    For the simultaneous detection of multiple tumor markers, we have fabricated ultra-long carbon nanotube sensors that can detect carcinoembryonic antigen (CEA) and prostate specific antigen (PSA), simultaneously. Ultra-long carbon nanotubes, several millimeters long, were grown by ethanol CVD, and fabricated as FET sensors by using conventional photolithography. To functionalize each segment of a single ultra-long nanotube device with multiple-tumor markers, we first functionalize the entire device with CDI-Tween 20 linking molecules, and then immobilized CEA and PSA antibodies using the microfluidic channel. The electrical conductance from CEA-antibody functionalized and PSA-antibody functionalized segment of a ultra-long carbon nanotube device was monitored simultaneously with Ag/AgCl reference electrode as a liquid gate. We will discuss the advantages of long-nanotube device in detail.

  15. Detection and identification of alkylating agents by using a bioinspired "chemical nose".

    Science.gov (United States)

    Hertzog-Ronen, Carmit; Borzin, Elena; Gerchikov, Yulia; Tessler, Nir; Eichen, Yoav

    2009-10-12

    Alkylating agents are simple and reactive molecules that are commonly used in many and diverse fields such as organic synthesis, medicine, and agriculture. Some highly reactive alkylating species are also being used as blister chemical-warfare agents. The detection and identification of alkylating agents is not a trivial issue because of their high reactivity and simple structure. Herein, we report on a new multispot luminescence-based approach to the detection and identification of alkylating agents. In order to demonstrate the potential of the approach, seven pi-conjugated oligomers and polymers bearing nucleophilic pyridine groups, 1-7, were adsorbed onto a solid support and exposed to vapors of alkylators 8-15. The alkylation-induced color-shift patterns of the seven-spot array allow clear discrimination of the different alkylators. The spots are sensitive to minute concentrations of alkylators and, because the detection is based on the formation of new covalent bonds, these spots saturate at about 50 ppb.

  16. Leak detection device on flange surface

    International Nuclear Information System (INIS)

    Hanai, Koi.

    1988-01-01

    Purpose: To improve the response to fine leakage thereby enabling to leakage detection at high sensitivity, by detecting the humidity by the use of an inert dry gas. Constitution: Annular grooves are coaxially engraved to a flange and an annular water channel groove is also engraved between each of the annular grooves. Dry nitrogen flown out is blown along the circumferential direction of the water channel grooves, turned there around and then released from the end of the pipeway. If there is any water leakage, the dry nitrogen absorbs leaked water to be wettened and then reach a humidity sensor. The sensor detects the humidity in the nitrogen and delivers an output into a signal processing circuit. The processing circuit judges the absence or presence of the leakage in accordance with the detected humidity to generate an alarm signal. The time required for the blown out dry nitrogen, which turn around the water channel groove and enter the sensor, is about several minutes and the device shows excellent response even for minute leakage. (Yoshino, Y.)

  17. Protection device for a thermonuclear device

    International Nuclear Information System (INIS)

    Kawashima, Shuichi.

    1986-01-01

    Purpose: To exactly detect the void coefficients of coolants even under high magnetic fields thereby detect the overheat of a thermonuclear device at an early stage. Constitution: The protecting device of this invention comprises a laser beam generation device, a laser beam detection device and an accident detection device. The laser generation device always generates laser beams, which are permeated through coolants and detected by the laser beam detection device, the optical amount of which is transmitted to the accident detection device. The accident detection device judges the excess or insufficiency of the detected optical amount with respect to the optical amount of the laser beams under the stationary state as a reference and issues an accident signal. Since only the optical cables that do not undergo the effect of the magnetic fields are exposed to high magnetic fields in the protection device of this invention, a high reliability can be maintained. (Kamimura, M.)

  18. Implanting inequality: empirical evidence of social and ethical risks of implantable radio-frequency identification (RFID) devices.

    Science.gov (United States)

    Monahan, Torin; Fisher, Jill A

    2010-10-01

    The aim of this study was to assess empirically the social and ethical risks associated with implantable radio-frequency identification (RFID) devices. Qualitative research included observational studies in twenty-three U.S. hospitals that have implemented new patient identification systems and eighty semi-structured interviews about the social and ethical implications of new patient identification systems, including RFID implants. The study identified three primary social and ethical risks associated with RFID implants: (i) unfair prioritization of patients based on their participation in the system, (ii) diminished trust of patients by care providers, and (iii) endangerment of patients who misunderstand the capabilities of the systems. RFID implants may aggravate inequalities in access to care without any clear health benefits. This research underscores the importance of critically evaluating new healthcare technologies from the perspective of both normative ethics and empirical ethics.

  19. Earth analysis methods, subsurface feature detection methods, earth analysis devices, and articles of manufacture

    Science.gov (United States)

    West, Phillip B [Idaho Falls, ID; Novascone, Stephen R [Idaho Falls, ID; Wright, Jerry P [Idaho Falls, ID

    2011-09-27

    Earth analysis methods, subsurface feature detection methods, earth analysis devices, and articles of manufacture are described. According to one embodiment, an earth analysis method includes engaging a device with the earth, analyzing the earth in a single substantially lineal direction using the device during the engaging, and providing information regarding a subsurface feature of the earth using the analysis.

  20. Genome-Enhanced Detection and Identification (GEDI of plant pathogens

    Directory of Open Access Journals (Sweden)

    Nicolas Feau

    2018-02-01

    Full Text Available Plant diseases caused by fungi and Oomycetes represent worldwide threats to crops and forest ecosystems. Effective prevention and appropriate management of emerging diseases rely on rapid detection and identification of the causal pathogens. The increase in genomic resources makes it possible to generate novel genome-enhanced DNA detection assays that can exploit whole genomes to discover candidate genes for pathogen detection. A pipeline was developed to identify genome regions that discriminate taxa or groups of taxa and can be converted into PCR assays. The modular pipeline is comprised of four components: (1 selection and genome sequencing of phylogenetically related taxa, (2 identification of clusters of orthologous genes, (3 elimination of false positives by filtering, and (4 assay design. This pipeline was applied to some of the most important plant pathogens across three broad taxonomic groups: Phytophthoras (Stramenopiles, Oomycota, Dothideomycetes (Fungi, Ascomycota and Pucciniales (Fungi, Basidiomycota. Comparison of 73 fungal and Oomycete genomes led the discovery of 5,939 gene clusters that were unique to the targeted taxa and an additional 535 that were common at higher taxonomic levels. Approximately 28% of the 299 tested were converted into qPCR assays that met our set of specificity criteria. This work demonstrates that a genome-wide approach can efficiently identify multiple taxon-specific genome regions that can be converted into highly specific PCR assays. The possibility to easily obtain multiple alternative regions to design highly specific qPCR assays should be of great help in tackling challenging cases for which higher taxon-resolution is needed.

  1. Development of Quantum Devices and Algorithms for Radiation Detection and Radiation Signal Processing

    International Nuclear Information System (INIS)

    El Tokhy, M.E.S.M.E.S.

    2012-01-01

    The main functions of spectroscopy system are signal detection, filtering and amplification, pileup detection and recovery, dead time correction, amplitude analysis and energy spectrum analysis. Safeguards isotopic measurements require the best spectrometer systems with excellent resolution, stability, efficiency and throughput. However, the resolution and throughput, which depend mainly on the detector, amplifier and the analog-to-digital converter (ADC), can still be improved. These modules have been in continuous development and improvement. For this reason we are interested with both the development of quantum detectors and efficient algorithms of the digital processing measurement. Therefore, the main objective of this thesis is concentrated on both 1. Study quantum dot (QD) devices behaviors under gamma radiation 2. Development of efficient algorithms for handling problems of gamma-ray spectroscopy For gamma radiation detection, a detailed study of nanotechnology QD sources and infrared photodetectors (QDIP) for gamma radiation detection is introduced. There are two different types of quantum scintillator detectors, which dominate the area of ionizing radiation measurements. These detectors are QD scintillator detectors and QDIP scintillator detectors. By comparison with traditional systems, quantum systems have less mass, require less volume, and consume less power. These factors are increasing the need for efficient detector for gamma-ray applications such as gamma-ray spectroscopy. Consequently, the nanocomposite materials based on semiconductor quantum dots has potential for radiation detection via scintillation was demonstrated in the literature. Therefore, this thesis presents a theoretical analysis for the characteristics of QD sources and infrared photodetectors (QDIPs). A model of QD sources under incident gamma radiation detection is developed. A novel methodology is introduced to characterize the effect of gamma radiation on QD devices. The rate

  2. A machine learning approach for indirect human presence detection using IoT devices

    OpenAIRE

    Madeira, Rui Nuno Neves

    2016-01-01

    The recent increased democratization of technology led to the appearance of new devices dedicated to the improvement of our daily living and working spaces, capable of being remotely controlled through the internet and interoperability with other systems. In this context, human presence detection is fundamental for several purposes, such has: further automization, usage pattern learning, problem detection (illness, or intruder), etc. Current intrusion detection devices usual...

  3. Chemical detection, identification, and analysis system

    International Nuclear Information System (INIS)

    Morel, R.S.; Gonzales, D.; Mniszewski, S.

    1990-01-01

    The chemical detection, identification, and analysis system (CDIAS) has three major goals. The first is to display safety information regarding chemical environment before personnel entry. The second is to archive personnel exposure to the environment. Third, the system assists users in identifying the stage of a chemical process in progress and suggests safety precautions associated with that process. In addition to these major goals, the system must be sufficiently compact to provide transportability, and it must be extremely simple to use in order to keep user interaction at a minimum. The system created to meet these goals includes several pieces of hardware and the integration of four software packages. The hardware consists of a low-oxygen, carbon monoxide, explosives, and hydrogen sulfide detector; an ion mobility spectrometer for airborne vapor detection; and a COMPAQ 386/20 portable computer. The software modules are a graphics kernel, an expert system shell, a data-base management system, and an interface management system. A supervisory module developed using the interface management system coordinates the interaction of the other software components. The system determines the safety of the environment using conventional data acquisition and analysis techniques. The low-oxygen, carbon monoxide, hydrogen sulfide, explosives, and vapor detectors are monitored for hazardous levels, and warnings are issued accordingly

  4. WE-G-204-08: Optimized Digital Radiographic Technique for Lost Surgical Devices/Needle Identification

    International Nuclear Information System (INIS)

    Gorman, A; Seabrook, G; Brakken, A; Dubois, M; Marn, C; Wilson, C; Jacobson, D; Liu, Y

    2015-01-01

    Purpose: Small surgical devices and needles are used in many surgical procedures. Conventionally, an x-ray film is taken to identify missing devices/needles if post procedure count is incorrect. There is no data to indicate smallest surgical devices/needles that can be identified with digital radiography (DR), and its optimized acquisition technique. Methods: In this study, the DR equipment used is a Canon RadPro mobile with CXDI-70c wireless DR plate, and the same DR plate on a fixed Siemens Multix unit. Small surgical devices and needles tested include Rubber Shod, Bulldog, Fogarty Hydrogrip, and needles with sizes 3-0 C-T1 through 8-0 BV175-6. They are imaged with PMMA block phantoms with thickness of 2–8 inch, and an abdomen phantom. Various DR techniques are used. Images are reviewed on the portable x-ray acquisition display, a clinical workstation, and a diagnostic workstation. Results: all small surgical devices and needles are visible in portable DR images with 2–8 inch of PMMA. However, when they are imaged with the abdomen phantom plus 2 inch of PMMA, needles smaller than 9.3 mm length can not be visualized at the optimized technique of 81 kV and 16 mAs. There is no significant difference in visualization with various techniques, or between mobile and fixed radiography unit. However, there is noticeable difference in visualizing the smallest needle on a diagnostic reading workstation compared to the acquisition display on a portable x-ray unit. Conclusion: DR images should be reviewed on a diagnostic reading workstation. Using optimized DR techniques, the smallest needle that can be identified on all phantom studies is 9.3 mm. Sample DR images of various small surgical devices/needles available on diagnostic workstation for comparison may improve their identification. Further in vivo study is needed to confirm the optimized digital radiography technique for identification of lost small surgical devices and needles

  5. Carbon nanotube-based sensing devices for human Arginase-1 detection

    Directory of Open Access Journals (Sweden)

    S. Baldo

    2016-03-01

    Full Text Available A new carbon nanotube-based device for detection of Arginase 1 (ARG-1 was produced. Multi-walled carbon nanotubes (MWCNTs were deposited between electrodes by dielectrophoresis (DEP in an accurate and reproducible way. This deposition method has the advantages of low cost and room temperature conditions and therefore, can be used on different kinds of substrates (silicon, glass, plastics allowing for large scale production of chemical or biological sensors. Scanning electrical microscope (SEM and electrical characterization have been performed on the biosensors before and after protein exposure. The devices were tested in the present work for the detection of ARG-1. They show high sensitivity and reproducibility, and can be easily and suitably modified to detect other proteins. Keywords: Carbon nanotube, Biosensor, Arginase, Dielectrophoresis, Biomarker, Protein

  6. Manufacturing and testing flexible microfluidic devices with optical and electrical detection mechanisms

    NARCIS (Netherlands)

    Ivan, M.G.; Vivet, F.; Meinders, E.R.

    2010-01-01

    Flexible microfluidic devices made of poly(dimethylsiloxane) (PDMS) were manufactured by soft lithography, and tested in detection of ionic species using optical absorption spectroscopy and electrical measurements. PDMS was chosen due to its flexibility and ease of surface modification by exposure

  7. Cue combination in a combined feature contrast detection and figure identification task.

    Science.gov (United States)

    Meinhardt, Günter; Persike, Malte; Mesenholl, Björn; Hagemann, Cordula

    2006-11-01

    Target figures defined by feature contrast in spatial frequency, orientation or both cues had to be detected in Gabor random fields and their shape had to be identified in a dual task paradigm. Performance improved with increasing feature contrast and was strongly correlated among both tasks. Subjects performed significantly better with combined cues than with single cues. The improvement due to cue summation was stronger than predicted by the assumption of independent feature specific mechanisms, and increased with the performance level achieved with single cues until it was limited by ceiling effects. Further, cue summation was also strongly correlated among tasks: when there was benefit due to the additional cue in feature contrast detection, there was also benefit in figure identification. For the same performance level achieved with single cues, cue summation was generally larger in figure identification than in feature contrast detection, indicating more benefit when processes of shape and surface formation are involved. Our results suggest that cue combination improves spatial form completion and figure-ground segregation in noisy environments, and therefore leads to more stable object vision.

  8. The BaBar detector for muon identification and neutral hadron detection

    International Nuclear Information System (INIS)

    Paolucci, P.; Evangelista, C.; Palano, A.; Baldini, R.; Calcaterra, A.; De Sangro, R.; Piccolo, M.; Zallo, A.; Peruzzi, I.; Buzzo, A.; Contri, R.; Crosetti, G.; Monge, R.; Passaggio, S.; Patrignani, C.; Pia, M.G.; Santroni, A.; Bionta, R.M.; van Bibber, K.; Wenaus, T.J.; Wright, D.M.; Cavallo, N.; Carlino, G.; Lista, L.; Mele, S.; Parascandolo, P.; Piccolo, D.; Sciacca, C.; Johnson, J.R.

    1996-01-01

    The BaBar experiment is projected to study CP violation in B decays. Muon detection and K L 0 identification are achieved by an instrumented flux return (IFR) system based on resistive plate chamber detectors. In this paper the general layout of the IFR system will be described. (orig.)

  9. Chemical warfare agent detection: a review of current trends and future perspective.

    Science.gov (United States)

    Pacsial-Ong, Eden Joy; Aguilar, Zoraida P

    2013-01-01

    The World Health Organization recommends countries to create a public health system that can respond to the deliberate release of chemical warfare agents (CWAs). Procedures for preparedness, response, decontamination protocols and medical countermeasures against CWA attacks are described. Known CWAs, including their properties and pharmacological consequences upon exposure, are tabulated and discussed. Requirements imposed on detection systems by various applications and environmental needs are presented in order to assess the devices for detection and identification of specific CWAs. The review surveys current and near-term detection technologies and equipments, as well as devices that are currently available to the military and civilian first responders. Brief technical discussions of several detection technologies are presented, with emphasis placed in the principles of detection. Finally, enabling technologies that form the basis for advanced sensing systems and devices are described.

  10. Monolithic integration of optical waveguides for absorbance detection in microfabricated electrophoresis devices

    DEFF Research Database (Denmark)

    Mogensen, Klaus Bo; Petersen, Nickolaj Jacob; Hübner, Jörg

    2001-01-01

    . The waveguides on the device were connected to optical fibers, which enabled alignment free operation due to the absence of free-space optics. A 750 mum long U-shaped detection cell was used to facilitate longitudinal absorption detection. To minimize geometrically induced band broadening at the turn in the U......The fabrication and performance of an electrophoretic separation chip with integrated of optical waveguides for absorption detection is presented. The device was fabricated on a silicon substrate by standard microfabrication techniques with the use of two photolithographic mask steps...

  11. Correlación vibroacústica: detección cognitiva e identificación de fallas. // Vibroacoustic correlation: Failure identification and cognoscitive detection

    Directory of Open Access Journals (Sweden)

    F. Miyara

    2000-03-01

    Full Text Available Se presenta una metodología para la investigación diagnóstica de fallas en máquinas industriales mediante un correladorvibroacústico, dispositivo que permite comparar automáticamente las frecuencias de una señal acústica y una vibratoria. Seconjuga así la habilidad humana para la detección de ruidos anómalos con la identificación objetiva de su procedencia.Palabras claves Acústica, ruido, vibraciones, correlación, fallas, identificación_____________________________________________________________________________AbstractA methodology for the diagnosis investigation of failure in industrial machines by means of a vibroacustic corelator ispresented, device that allow to compare the frecuencies of an acoustic signal and a vibratory one automatically.In this waythe human ability for the detection of anomalous noises is conjugated with the objective identification of their origin.Key words: Acoustic, Noise, Vibrations, Correlation, Failure Identification.

  12. The use of silicon devices (diodes, RAMs, etc.) for alpha particle detection

    International Nuclear Information System (INIS)

    Agosteo, S.; Foglio Para, A.

    1993-01-01

    Silicon electronic devices (diodes, random access memories (RAMs), etc.) can be employed in alpha particle detection and spectroscopy with a good energy resolution. The detection mechanisms are first discussed; the performances of these devices operating in the pulse and in the current mode are then described starting from the pioneering works of the last decade. Some peculiar applications of RAMs are finally reported. (author). 7 refs, 5 figs, 1 tab

  13. Automated real-time detection of tonic-clonic seizures using a wearable EMG device

    DEFF Research Database (Denmark)

    Beniczky, Sándor; Conradsen, Isa; Henning, Oliver

    2018-01-01

    OBJECTIVE: To determine the accuracy of automated detection of generalized tonic-clonic seizures (GTCS) using a wearable surface EMG device. METHODS: We prospectively tested the technical performance and diagnostic accuracy of real-time seizure detection using a wearable surface EMG device....... The seizure detection algorithm and the cutoff values were prespecified. A total of 71 patients, referred to long-term video-EEG monitoring, on suspicion of GTCS, were recruited in 3 centers. Seizure detection was real-time and fully automated. The reference standard was the evaluation of video-EEG recordings...

  14. Radiation transmission type pipe wall thinning detection device and measuring instruments utilizing ionizing radiation

    International Nuclear Information System (INIS)

    Higashi, Yasuhiko

    2009-01-01

    We developed the device to detect thinning of pipe thorough heat insulation in Power Plant, etc, even while the plant is under operation. It is necessary to test many parts of many pipes for pipe wall thinning management, but it is difficult within a limited time of the routine test. This device consists of detector and radiation source, which can detect the pipe (less than 500 mm in external diameter, less than 50 mm in thickness) with 1.6%-reproducibility (in a few-minutes measurement), based on the attenuation rate. Operation is easy and effective without removing the heat insulation. We will expand this thinning detection system, and contribute the safety of the Plant. (author)

  15. Ultrasound detection and identification of cosmetic fillers in the skin

    DEFF Research Database (Denmark)

    Wortsman, X.; Wortsman, J.; Orlandi, C.

    2012-01-01

    Background While the incidence of cosmetic filler injections is rising world-wide, neither exact details of the procedure nor the agent used are always reported or remembered by the patients. Thus, although complications are reportedly rare, availability of a precise diagnostic tool to detect...... cutaneous filler deposits could help clarify the association between the procedure and the underlying pathology. Objectives The aim of this study was to evaluate cutaneous sonography in the detection and identification of cosmetic fillers deposits and, describe dermatological abnormalities found associated...... with the presence of those agents. Methods We used ultrasound in a porcine skin model to determine the sonographic characteristics of commonly available filler agents, and subsequently applied the analysis to detect and identify cosmetic fillers among patients referred for skin disorders. Results Fillers...

  16. The new generation of detection and identification equipment; Nouvelle generation de materiel de detection et d' identification

    Energy Technology Data Exchange (ETDEWEB)

    Schultz, F.; Guerin, M.; Fort, Ph. [Mirion technologies, division HPH, BPI - 13113 Lamanon (France)

    2009-07-01

    The authors address the highly sensitive detection issue with real time identification of the risk nature, a problem which occurs every time a source is only fleetingly present (a pedestrian, a vehicle or an object on a conveyor belt passing by). They briefly present a range of instruments specially designed for this purpose, the SPIR-Ident instruments. These equipment use one or several large sensors, digital multichannel analyzers (one per sensor) and neutron and gamma measurements. Spectra are continuously processed, stabilized, linearized and normalized, and finally analyzed by an algorithm. The authors evoke the performance characterization and a return on experience after a 6 month-use for the control of passengers and luggage in airport

  17. Organic materials and devices for detecting ionizing radiation

    Science.gov (United States)

    Doty, F Patrick [Livermore, CA; Chinn, Douglas A [Livermore, CA

    2007-03-06

    A .pi.-conjugated organic material for detecting ionizing radiation, and particularly for detecting low energy fission neutrons. The .pi.-conjugated materials comprise a class of organic materials whose members are intrinsic semiconducting materials. Included in this class are .pi.-conjugated polymers, polyaromatic hydrocarbon molecules, and quinolates. Because of their high resistivities (.gtoreq.10.sup.9 ohmcm), these .pi.-conjugated organic materials exhibit very low leakage currents. A device for detecting and measuring ionizing radiation can be made by applying an electric field to a layer of the .pi.-conjugated polymer material to measure electron/hole pair formation. A layer of the .pi.-conjugated polymer material can be made by conventional polymer fabrication methods and can be cast into sheets capable of covering large areas. These sheets of polymer radiation detector material can be deposited between flexible electrodes and rolled up to form a radiation detector occupying a small volume but having a large surface area. The semiconducting polymer material can be easily fabricated in layers about 10 .mu.m to 100 .mu.m thick. These thin polymer layers and their associated electrodes can be stacked to form unique multi-layer detector arrangements that occupy small volume.

  18. Subtle pulmonary nodules: detection and identification with storage phosphor radiographs and conventional chest films

    International Nuclear Information System (INIS)

    Scheck, R.J.; Schaetzl, M.; Kandziora, C.; Panzer, M.; Rienmueller, R.

    1994-01-01

    To determine the value of digital storagephosphor radiography (SR) on the detection and identification of subtle lung nodules, postero-anterior (PA) and lateral (LAT) film-screen (FR) chest radiographs were compared with isodose SR images of 45 patients with metastatic malignancies. The SR postprocessing was done with a particular mode previously optimized for routine chest radiography. Pulmonary metastases were found in 34 patients and were proved or excluded by CT (n=28) or longterm follow-up FR (n=17). Chest images were divided into four regions for evaluation of image quality, number of lung nodules per region and marked pulmonary structures by receiver-operating characteristics (ROC) analysis (45 patients; 125 nodules; 2810 observations; five readers). Of the nodules selected for an ROC study 82% were 0.5-1.0 cm in diameter. Overall image quality was rated better for FR concerning lung fields (PA) and mediastinum/hilum (LAT). More lung-field nodules were detected on FR than on SR chest images. Use of FR was superior to SR in the general identification of nodules (PA chest), especially concerning intermediate and subtle abnormalities, whereas there was no significant difference for LAT chest images. Our results show, that currently FR still has advantages over SR in the detection and identification of subtle lung nodules in routine clinical radiography. (orig.)

  19. Recent Developments in Optical Detection Technologies in Lab-on-a-Chip Devices for Biosensing Applications

    Directory of Open Access Journals (Sweden)

    Nuno Miguel Matos Pires

    2014-08-01

    Full Text Available The field of microfluidics has yet to develop practical devices that provide real clinical value. One of the main reasons for this is the difficulty in realizing low-cost, sensitive, reproducible, and portable analyte detection microfluidic systems. Previous research has addressed two main approaches for the detection technologies in lab-on-a-chip devices: (a study of the compatibility of conventional instrumentation with microfluidic structures, and (b integration of innovative sensors contained within the microfluidic system. Despite the recent advances in electrochemical and mechanical based sensors, their drawbacks pose important challenges to their application in disposable microfluidic devices. Instead, optical detection remains an attractive solution for lab-on-a-chip devices, because of the ubiquity of the optical methods in the laboratory. Besides, robust and cost-effective devices for use in the field can be realized by integrating proper optical detection technologies on chips. This review examines the recent developments in detection technologies applied to microfluidic biosensors, especially addressing several optical methods, including fluorescence, chemiluminescence, absorbance and surface plasmon resonance.

  20. Ultrasonic wave damage detecting device

    International Nuclear Information System (INIS)

    Miura, Yuichi; Nagao, Tetsuya; Nishi, Yuji; Kubota, Keisuke; Maruyama, Takayuki.

    1994-01-01

    Upon detecting a damage for a joint between a connecting nozzle at the outer circumference of a reactor pressure vessel and pipelines, the present invention greatly shortens the operation time. That is, it is noted that the connecting nozzle has a tapered portion and a small-diameter portion in view of strength. A main magnetic wheel supported on a base of a running vehicle is attracted to the small-diameter portion and an auxiliary magnet wheel is attracted to the tapered portion respectively and they are rolled. This regulate the deviation of the position of the base of the running vehicle in axial direction of the nozzle by the small-diameter portion and the tapered portion. Accordingly, the running vehicle can be circulated along a predetermined course on the outer circumference of the connecting nozzle without using tracks such as an existent ring track. The test can be performed conveniently only by placing the damage detecting device on the connecting nozzle. As a result, preparation time required before the test can remarkably be shortened. (I.S.)

  1. Evaluation of novel algorithm embedded in a wearable sEMG device for seizure detection

    DEFF Research Database (Denmark)

    Conradsen, Isa; Beniczky, Sandor; Wolf, Peter

    2012-01-01

    We implemented a modified version of a previously published algorithm for detection of generalized tonic-clonic seizures into a prototype wireless surface electromyography (sEMG) recording device. The method was modified to require minimum computational load, and two parameters were trained...... on prior sEMG data recorded with the device. Along with the normal sEMG recording, the device is able to set an alarm whenever the implemented algorithm detects a seizure. These alarms are annotated in the data file along with the signal. The device was tested at the Epilepsy Monitoring Unit (EMU......) at the Danish Epilepsy Center. Five patients were included in the study and two of them had generalized tonic-clonic seizures. All patients were monitored for 2–5 days. A double-blind study was made on the five patients. The overall result showed that the device detected four of seven seizures and had a false...

  2. A miniaturized silicon based device for nucleic acids electrochemical detection

    Directory of Open Access Journals (Sweden)

    Salvatore Petralia

    2015-12-01

    Full Text Available In this paper we describe a novel portable system for nucleic acids electrochemical detection. The core of the system is a miniaturized silicon chip composed by planar microelectrodes. The chip is embedded on PCB board for the electrical driving and reading. The counter, reference and work microelectrodes are manufactured using the VLSI technology, the material is gold for reference and counter electrodes and platinum for working electrode. The device contains also a resistor to control and measuring the temperature for PCR thermal cycling. The reaction chamber has a total volume of 20 μL. It is made in hybrid silicon–plastic technology. Each device contains four independent electrochemical cells.Results show HBV Hepatitis-B virus detection using an unspecific DNA intercalating redox probe based on metal–organic compounds. The recognition event is sensitively detected by square wave voltammetry monitoring the redox signals of the intercalator that strongly binds to the double-stranded DNA. Two approaches were here evaluated: (a intercalation of electrochemical unspecific probe on ds-DNA on homogeneous solution (homogeneous phase; (b grafting of DNA probes on electrode surface (solid phase.The system and the method here reported offer better advantages in term of analytical performances compared to the standard commercial optical-based real-time PCR systems, with the additional incomes of being potentially cheaper and easier to integrate in a miniaturized device. Keywords: Electrochemical detection, Real time PCR, Unspecific DNA intercalator

  3. A study of malware detection on smart mobile devices

    Science.gov (United States)

    Yu, Wei; Zhang, Hanlin; Xu, Guobin

    2013-05-01

    The growing in use of smart mobile devices for everyday applications has stimulated the spread of mobile malware, especially on popular mobile platforms. As a consequence, malware detection becomes ever more critical in sustaining the mobile market and providing a better user experience. In this paper, we review the existing malware and detection schemes. Using real-world malware samples with known signatures, we evaluate four popular commercial anti-virus tools and our data shows that these tools can achieve high detection accuracy. To deal with the new malware with unknown signatures, we study the anomaly based detection using decision tree algorithm. We evaluate the effectiveness of our detection scheme using malware and legitimate software samples. Our data shows that the detection scheme using decision tree can achieve a detection rate up to 90% and a false positive rate as low as 10%.

  4. Identification of microfluidic two-phase flow patterns in lab-on-chip devices.

    Science.gov (United States)

    Yang, Zhaochu; Dong, Tao; Halvorsen, Einar

    2014-01-01

    This work describes a capacitive sensor for identification of microfluidic two-phase flow in lab-on-chip devices. With interdigital electrodes and thin insulation layer utilized, this sensor is capable of being integrated with the microsystems easily. Transducing principle and design considerations are presented with respect to the microfluidic gas/liquid flow patterns. Numerical simulation results verify the operational principle. And the factors affecting the performance of the sensor are discussed. Besides, a feasible process flow for the fabrication is also proposed.

  5. Autonomous system for pathogen detection and identification

    International Nuclear Information System (INIS)

    Belgrader, P.; Benett, W.; Langlois, R.; Long, G.; Mariella, R.; Milanovich, F.; Miles, R.; Nelson, W.; Venkateswaran, K.

    1998-01-01

    This purpose of this project is to build a prototype instrument that will, running unattended, detect, identify, and quantify BW agents. In order to accomplish this, we have chosen to start with the world s leading, proven, assays for pathogens: surface-molecular recognition assays, such as antibody-based assays, implemented on a high-performance, identification (ID)-capable flow cytometer, and the polymerase chain reaction (PCR) for nucleic-acid based assays. With these assays, we must integrate the capability to: l collect samples from aerosols, water, or surfaces; l perform sample preparation prior to the assays; l incubate the prepared samples, if necessary, for a period of time; l transport the prepared, incubated samples to the assays; l perform the assays; l interpret and report the results of the assays. Issues such as reliability, sensitivity and accuracy, quantity of consumables, maintenance schedule, etc. must be addressed satisfactorily to the end user. The highest possible sensitivity and specificity of the assay must be combined with no false alarms. Today, we have assays that can, in under 30 minutes, detect and identify stimulants for BW agents at concentrations of a few hundred colony-forming units per ml of solution. If the bio-aerosol sampler of this system collects 1000 Ymin and concentrates the respirable particles into 1 ml of solution with 70% processing efficiency over a period of 5 minutes, then this translates to a detection/ID capability of under 0.1 agent-containing particle/liter of air

  6. Microfluidic biosensing device for controlled trapping and detection of magnetic microparticles

    KAUST Repository

    Giouroudi, Ioanna

    2013-05-01

    A magnetic microfluidic device is proposed to transport and trap magnetic microparticles (MPs) to a sensing area. Once the MPs are concentrated in the vicinity of the sensing area, a spin valve type giant magnetoresistance (GMR) sensor is used to detect their presence. The device is used for the detection of biological targets once they are labeled with functionalized MPs. Manipulation of the MPs is achieved by employing a microstructure which consists of planar ringshaped conducting microloops. These microloops are designed to produce high magnetic field gradients which are directly proportional to the force applied to manipulate the MPs. Upon sequential application of current, starting from the outermost loop, MPs are directed to move from the outermost to the innermost loop. The speed with which the MPs move towards the sensing area is controlled by the speed with which current is switched between the loops. On top of the microstructure, a microfluidic channel is fabricated using a standard photolithography technique and a dry film resist layer (Ordyl SY355). Experimental results showed that MPs of different diameters were successfully trapped at the sensing area and detected by the GMR sensor located directly under the innermost square loop. © 2013 IEEE.

  7. Device for Detection of Explosives, Nuclear and Other Hazardous Materials in Luggage and Cargo Containers

    International Nuclear Information System (INIS)

    Kuznetsov, Andrey; Evsenin, Alexey; Osetrov, Oleg; Vakhtin, Dmitry; Gorshkov, Igor

    2009-01-01

    Device for detection of explosives, radioactive and heavily shielded nuclear materials in luggage and cargo containers based on Nanosecond Neutron Analysis/Associated Particles Technique (NNA/APT) is under construction. Detection module consists of a small neutron generator with built-in position-sensitive detector of associated alpha-particles, and several scintillator-based gamma-ray detectors. Explosives and other hazardous chemicals are detected by analyzing secondary high-energy gamma-rays from reactions of fast neutrons with materials inside a container. The same gamma-ray detectors are used to detect unshielded radioactive and nuclear materials. An array of several neutron detectors is used to detect fast neutrons from induced fission of nuclear materials. Coincidence and timing analysis allows one to discriminate between fission neutrons and scattered probing neutrons. Mathematical modeling by MCNP5 and MCNP-PoliMi codes was used to estimate the sensitivity of the device and its optimal configuration. Comparison of the features of three gamma detector types--based on BGO, NaI and LaBr 3 crystals is presented.

  8. Device for Detection of Explosives, Nuclear and Other Hazardous Materials in Luggage and Cargo Containers

    Science.gov (United States)

    Kuznetsov, Andrey; Evsenin, Alexey; Gorshkov, Igor; Osetrov, Oleg; Vakhtin, Dmitry

    2009-12-01

    Device for detection of explosives, radioactive and heavily shielded nuclear materials in luggage and cargo containers based on Nanosecond Neutron Analysis/Associated Particles Technique (NNA/APT) is under construction. Detection module consists of a small neutron generator with built-in position-sensitive detector of associated alpha-particles, and several scintillator-based gamma-ray detectors. Explosives and other hazardous chemicals are detected by analyzing secondary high-energy gamma-rays from reactions of fast neutrons with materials inside a container. The same gamma-ray detectors are used to detect unshielded radioactive and nuclear materials. An array of several neutron detectors is used to detect fast neutrons from induced fission of nuclear materials. Coincidence and timing analysis allows one to discriminate between fission neutrons and scattered probing neutrons. Mathematical modeling by MCNP5 and MCNP-PoliMi codes was used to estimate the sensitivity of the device and its optimal configuration. Comparison of the features of three gamma detector types—based on BGO, NaI and LaBr3 crystals is presented.

  9. Rapid detection and identification of viral and bacterial fish pathogens using a DNA array‐based multiplex assay

    DEFF Research Database (Denmark)

    Lievens, B.; Frans, I.; Heusdens, C.

    2011-01-01

    for the simultaneous detection and identification of all cyprinid herpesviruses (CyHV‐1, CyHV‐2 and CyHV‐3) and some of the most important fish pathogenic Flavobacterium species, including F. branchiophilum, F. columnare and F. psychrophilum. For virus identification, the DNA polymerase and helicase genes were...

  10. 21 CFR 864.7280 - Factor V Leiden DNA mutation detection systems.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Factor V Leiden DNA mutation detection systems....7280 Factor V Leiden DNA mutation detection systems. (a) Identification. Factor V Leiden deoxyribonucleic acid (DNA) mutation detection systems are devices that consist of different reagents and...

  11. Detection and Identification of Multiple Stationary Human Targets Via Bio-Radar Based on the Cross-Correlation Method

    Directory of Open Access Journals (Sweden)

    Yang Zhang

    2016-10-01

    Full Text Available Ultra-wideband (UWB radar has been widely used for detecting human physiological signals (respiration, movement, etc. in the fields of rescue, security, and medicine owing to its high penetrability and range resolution. In these applications, especially in rescue after disaster (earthquake, collapse, mine accident, etc., the presence, number, and location of the trapped victims to be detected and rescued are the key issues of concern. Ample research has been done on the first issue, whereas the identification and localization of multi-targets remains a challenge. False positive and negative identification results are two common problems associated with the detection of multiple stationary human targets. This is mainly because the energy of the signal reflected from the target close to the receiving antenna is considerably stronger than those of the targets at further range, often leading to missing or false recognition if the identification method is based on the energy of the respiratory signal. Therefore, a novel method based on cross-correlation is proposed in this paper that is based on the relativity and periodicity of the signals, rather than on the energy. The validity of this method is confirmed through experiments using different scenarios; the results indicate a discernible improvement in the detection precision and identification of the multiple stationary targets.

  12. Detection and Identification of Multiple Stationary Human Targets Via Bio-Radar Based on the Cross-Correlation Method.

    Science.gov (United States)

    Zhang, Yang; Chen, Fuming; Xue, Huijun; Li, Zhao; An, Qiang; Wang, Jianqi; Zhang, Yang

    2016-10-27

    Ultra-wideband (UWB) radar has been widely used for detecting human physiological signals (respiration, movement, etc.) in the fields of rescue, security, and medicine owing to its high penetrability and range resolution. In these applications, especially in rescue after disaster (earthquake, collapse, mine accident, etc.), the presence, number, and location of the trapped victims to be detected and rescued are the key issues of concern. Ample research has been done on the first issue, whereas the identification and localization of multi-targets remains a challenge. False positive and negative identification results are two common problems associated with the detection of multiple stationary human targets. This is mainly because the energy of the signal reflected from the target close to the receiving antenna is considerably stronger than those of the targets at further range, often leading to missing or false recognition if the identification method is based on the energy of the respiratory signal. Therefore, a novel method based on cross-correlation is proposed in this paper that is based on the relativity and periodicity of the signals, rather than on the energy. The validity of this method is confirmed through experiments using different scenarios; the results indicate a discernible improvement in the detection precision and identification of the multiple stationary targets.

  13. Zero-Power Radio Device.

    Energy Technology Data Exchange (ETDEWEB)

    Brocato, Robert W. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2018-02-01

    This report describes an unpowered radio receiver capable of detecting and responding to weak signals transmit ted from comparatively long distances . This radio receiver offers key advantages over a short range zero - power radio receiver previously described in SAND2004 - 4610, A Zero - Power Radio Receiver . The device described here can be fabricated as an integrated circuit for use in portable wireless devices, as a wake - up circuit, or a s a stand - alone receiver operating in conjunction with identification decoders or other electroni cs. It builds on key sub - components developed at Sandia National Laboratories over many years. It uses surface acoustic wave (SAW) filter technology. It uses custom component design to enable the efficient use of small aperture antennas. This device uses a key component, the pyroelectric demodulator , covered by Sandia owned U.S. Patent 7397301, Pyroelectric Demodulating Detector [1] . This device is also described in Sandia owned U.S. Patent 97266446, Zero Power Receiver [2].

  14. Microchip-based electrochemical detection using a 3-D printed wall-jet electrode device.

    Science.gov (United States)

    Munshi, Akash S; Martin, R Scott

    2016-02-07

    Three dimensional (3-D) printing technology has evolved dramatically in the last few years, offering the capability of printing objects with a variety of materials. Printing microfluidic devices using this technology offers various advantages such as ease and uniformity of fabrication, file sharing between laboratories, and increased device-to-device reproducibility. One unique aspect of this technology, when used with electrochemical detection, is the ability to produce a microfluidic device as one unit while also allowing the reuse of the device and electrode for multiple analyses. Here we present an alternate electrode configuration for microfluidic devices, a wall-jet electrode (WJE) approach, created by 3-D printing. Using microchip-based flow injection analysis, we compared the WJE design with the conventionally used thin-layer electrode (TLE) design. It was found that the optimized WJE system enhances analytical performance (as compared to the TLE design), with improvements in sensitivity and the limit of detection. Experiments were conducted using two working electrodes - 500 μm platinum and 1 mm glassy carbon. Using the 500 μm platinum electrode the calibration sensitivity was 16 times higher for the WJE device (as compared to the TLE design). In addition, use of the 1 mm glassy carbon electrode led to limit of detection of 500 nM for catechol, as compared to 6 μM for the TLE device. Finally, to demonstrate the versatility and applicability of the 3-D printed WJE approach, the device was used as an inexpensive electrochemical detector for HPLC. The number of theoretical plates was comparable to the use of commercially available UV and MS detectors, with the WJE device being inexpensive to utilize. These results show that 3-D-printing can be a powerful tool to fabricate reusable and integrated microfluidic detectors in configurations that are not easily achieved with more traditional lithographic methods.

  15. Molecular-Based Identification and Detection of Salmonella in Food Production Systems: Current Perspectives.

    Science.gov (United States)

    Ricke, Steven C; Kim, Sun Ae; Shi, Zhaohao; Park, Si Hong

    2018-04-19

    Salmonella remains a prominent cause of foodborne illnesses and can originate from a wide range of food products. Given the continued presence of pathogenic Salmonella in food production systems, there is a consistent need to improve identification and detection methods that can identify this pathogen at all stages in food systems. Methods for subtyping have evolved over the years, and the introduction of whole genome sequencing and advancements in PCR technologies has greatly improved the resolution for differentiating strains within a particular serovar. This, in turn, has led to the continued improvement in Salmonella detection technologies for utilization in food production systems. In this review, the focus will be on recent advancements in these technologies, as well as potential issues associated with the application of these tools in food production. In addition, the recent and emerging research developments on Salmonella detection and identification methodologies and their potential application in food production systems will be discussed. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  16. Detection of biosurfactants in Bacillus species: genes and products identification.

    Science.gov (United States)

    Płaza, G; Chojniak, J; Rudnicka, K; Paraszkiewicz, K; Bernat, P

    2015-10-01

    To screen environmental Bacillus strains for detection of genes encoding the enzymes involved in biosurfactant synthesis and to evaluate their products e.g. surfactin, iturin and fengycin. The taxonomic identification of isolated from the environment Bacillus strains was performed by Microgene ID Bacillus panel and GEN III Biolog system. The polymerase chain reaction (PCR) strategy for screening of genes in Bacillus strains was set up. Liquid chromatography-mass spectrometry (LC-MS/MS) method was used for the identification of lipopeptides (LPs). All studied strains exhibited the presence of srfAA gene and produced surfactin mostly as four homologues (C13 to C16). Moreover, in 2 strains (KP7, T'-1) simultaneous co-production of 3 biosurfactants: surfactin, iturin and fengycin was observed. Additionally, it was found out that isolate identified as Bacillus subtilis ssp. subtilis (KP7), beside LPs co-production, synthesizes surfactin with the efficiency much higher than other studied strains (40·2 mg l(-1) ) and with the yield ranging from 0·8 to 8·3 mg l(-1) . We showed that the combined methodology based on PCR and LC-MS/MS technique is an optimal tool for the detection of genes encoding enzymes involved in biosurfactant synthesis as well as their products, e.g. surfactin, iturin and fengycin. This approach improves the screening and the identification of environmental Bacillus co-producing biosurfactants-stimulating and facilitating the development of this area of science. The findings of this work will help to improve screening of biosurfactant producers. Discovery of novel biosurfactants and biosurfactants co-production ability has shed light on their new application fields and for the understanding of their interactions and properties. © 2015 The Society for Applied Microbiology.

  17. Counterbalanced radiation detection device

    International Nuclear Information System (INIS)

    Platz, W.

    1986-01-01

    A counterbalanced radiation detection device is described which consists of: (a) a base; (b) a radiation detector having a known weight; (c) means connected with the radiation detector and the base for positioning the radiation detector in different heights with respect to the base; (d) electronic component means movably mounted on the base for counterbalancing the weight of the radiation detector; (e) means connected with the electronic component means and the radiation detector positioning means for positioning the electronic component means in different heights with respect to the base opposite to the heights of the radiation detector; (f) means connected with the radiation detector and the base for shifting the radiation detector horizontally with respect to the base; and (g) means connected with the electronic component means and the radiation detector shifting means for shifting the electronic component means horizontally with respect to the base in opposite direction to shifting of the radiation detector

  18. Clinical accuracy of a PLEX-ID flu device for simultaneous detection and identification of influenza viruses A and B.

    Science.gov (United States)

    Tang, Yi-Wei; Lowery, Kristin S; Valsamakis, Alexandra; Schaefer, Virginia C; Chappell, James D; White-Abell, Jill; Quinn, Criziel D; Li, Haijing; Washington, Cicely A; Cromwell, Jenna; Giamanco, Chantel M; Forman, Michael; Holden, Jeffery; Rothman, Richard E; Parker, Michelle L; Ortenberg, Elaine V; Zhang, Lei; Lin, Yea-Lin; Gaydos, Charlotte A

    2013-01-01

    influenza A virus detection and H1N1-p subtyping. The PLEX-ID Flu assay demonstrated a high level of accuracy for the simultaneous detection and identification of influenza A and B viruses in patient specimens, providing a new laboratory tool for the rapid diagnosis and management of influenza A and B virus infections.

  19. Identification of volatiles by headspace gas chromatography with simultaneous flame ionization and mass spectrometric detection.

    Science.gov (United States)

    Tiscione, Nicholas B; Yeatman, Dustin Tate; Shan, Xiaoqin; Kahl, Joseph H

    2013-10-01

    Volatiles are frequently abused as inhalants. The methods used for identification are generally nonspecific if analyzed concurrently with ethanol or require an additional analytical procedure that employs mass spectrometry. A previously published technique utilizing a capillary flow technology splitter to simultaneously quantitate and confirm ethyl alcohol by flame ionization and mass spectrometric detection after headspace sampling and gas chromatographic separation was evaluated for the detection of inhalants. Methanol, isopropanol, acetone, acetaldehyde, toluene, methyl ethyl ketone, isoamyl alcohol, isobutyl alcohol, n-butyl alcohol, 1,1-difluoroethane, 1,1,1-trifluoroethane, 1,1,1,2-tetrafluoroethane (Norflurane, HFC-134a), chloroethane, trichlorofluoromethane (Freon®-11), dichlorodifluoromethane (Freon®-12), dichlorofluoromethane (Freon®-21), chlorodifluoromethane (Freon®-22) and 1,2-dichlorotetrafluoroethane (Freon®-114) were validated for qualitative identification by this method. The validation for qualitative identification included evaluation of matrix effects, sensitivity, carryover, specificity, repeatability and ruggedness/robustness.

  20. The new generation of detection and identification equipment

    International Nuclear Information System (INIS)

    Schultz, F.; Guerin, M.; Fort, Ph.

    2009-01-01

    The authors address the highly sensitive detection issue with real time identification of the risk nature, a problem which occurs every time a source is only fleetingly present (a pedestrian, a vehicle or an object on a conveyor belt passing by). They briefly present a range of instruments specially designed for this purpose, the SPIR-Ident instruments. These equipment use one or several large sensors, digital multichannel analyzers (one per sensor) and neutron and gamma measurements. Spectra are continuously processed, stabilized, linearized and normalized, and finally analyzed by an algorithm. The authors evoke the performance characterization and a return on experience after a 6 month-use for the control of passengers and luggage in airport

  1. Methods of the Detection and Identification of Structural Defects in Saturated Metallic Composite Castings

    Directory of Open Access Journals (Sweden)

    Gawdzińska K.

    2017-09-01

    Full Text Available Diagnostics of composite castings, due to their complex structure, requires that their characteristics are tested by an appropriate description method. Any deviation from the specific characteristic will be regarded as a material defect. The detection of defects in composite castings sometimes is not sufficient and the defects have to be identified. This study classifies defects found in the structures of saturated metallic composite castings and indicates those stages of the process where such defects are likely to be formed. Not only does the author determine the causes of structural defects, describe methods of their detection and identification, but also proposes a schematic procedure to be followed during detection and identification of structural defects of castings made from saturated reinforcement metallic composites. Alloys examination was conducted after technological process, while using destructive (macroscopic tests, light and scanning electron microscopy and non-destructive (ultrasonic and X-ray defectoscopy, tomography, gravimetric method methods. Research presented in this article are part of author’s work on castings quality.

  2. Asymmetric devices based on carbon nanotubes for terahertz-range radiation detection

    Energy Technology Data Exchange (ETDEWEB)

    Fedorov, G. E., E-mail: gefedorov@mail.ru; Stepanova, T. S.; Gazaliev, A. Sh.; Gaiduchenko, I. A.; Kaurova, N. S.; Voronov, B. M.; Goltzman, G. N. [Moscow State Pedagogical University (Russian Federation)

    2016-12-15

    Various asymmetric detecting devices based on carbon nanotubes (CNTs) are studied. The asymmetry is understood as inhomogeneous properties along the conducting channel. In the first type of devices, an inhomogeneous morphology of the CNT grid is used. In the second type of devices, metals with highly varying work functions are used as the contact material. The relation between the sensitivity and detector configuration is analyzed. Based on the data obtained, approaches to the development of an efficient detector of terahertz radiation, based on carbon nanotubes are proposed.

  3. Partial fingerprint identification algorithm based on the modified generalized Hough transform on mobile device

    Science.gov (United States)

    Qin, Jin; Tang, Siqi; Han, Congying; Guo, Tiande

    2018-04-01

    Partial fingerprint identification technology which is mainly used in device with small sensor area like cellphone, U disk and computer, has taken more attention in recent years with its unique advantages. However, owing to the lack of sufficient minutiae points, the conventional method do not perform well in the above situation. We propose a new fingerprint matching technique which utilizes ridges as features to deal with partial fingerprint images and combines the modified generalized Hough transform and scoring strategy based on machine learning. The algorithm can effectively meet the real-time and space-saving requirements of the resource constrained devices. Experiments on in-house database indicate that the proposed algorithm have an excellent performance.

  4. Detection and identification of explosives and illicit drugs using neutron based techniques

    International Nuclear Information System (INIS)

    Papp, A.; Csikai, J.; Debrecen University,

    2011-01-01

    Some methods developed in collaboration between the ATOMKI and IEP for bulk hydrogen analysis and for the detection and identification of illicit drugs are presented. Advantages and limitations of neutron techniques (reflection, transmission, elastic and inelastic scatterings, leakage spectra and angular yields of Be(d,n), Pu-Be, D-D, D-T and 252 Cf neutrons transmitted from thick samples, effects of hidden materials) are discussed. (author)

  5. Detection, recognition, identification, and tracking of military vehicles using biomimetic intelligence

    Science.gov (United States)

    Pace, Paul W.; Sutherland, John

    2001-10-01

    This project is aimed at analyzing EO/IR images to provide automatic target detection/recognition/identification (ATR/D/I) of militarily relevant land targets. An increase in performance was accomplished using a biomimetic intelligence system functioning on low-cost, commercially available processing chips. Biomimetic intelligence has demonstrated advanced capabilities in the areas of hand- printed character recognition, real-time detection/identification of multiple faces in full 3D perspectives in cluttered environments, advanced capabilities in classification of ground-based military vehicles from SAR, and real-time ATR/D/I of ground-based military vehicles from EO/IR/HRR data in cluttered environments. The investigation applied these tools to real data sets and examined the parameters such as the minimum resolution for target recognition, the effect of target size, rotation, line-of-sight changes, contrast, partial obscuring, background clutter etc. The results demonstrated a real-time ATR/D/I capability against a subset of militarily relevant land targets operating in a realistic scenario. Typical results on the initial EO/IR data indicate probabilities of correct classification of resolved targets to be greater than 95 percent.

  6. Confidence in word detection predicts word identification: implications for an unconscious perception paradigm.

    Science.gov (United States)

    Haase, S J; Fisk, G

    2001-01-01

    The present experiments extend the scope of the independent observation model based on signal detection theory (Macmillan & Creelman, 1991) to complex (word) stimulus sets. In the first experiment, the model predicts the relationship between uncertain detection and subsequent correct identification, thereby providing an alternative interpretation to a phenomenon often described as unconscious perception. Our second experiment used an exclusion task (Jacoby, Toth, & Yonelinas, 1993), which, according to theories of unconscious perception, should show qualitative differences in performance based on stimulus detection accuracy and provide a relative measure of conscious versus unconscious influences (Merikle, Joordens, & Stoltz, 1995). Exclusion performance was also explained by the model, suggesting that undetected words did not unconsciously influence identification responses.

  7. A portable cell-based optical detection device for rapid detection of Listeria and Bacillus toxins

    Science.gov (United States)

    Banerjee, Pratik; Banada, Padmapriya P.; Rickus, Jenna L.; Morgan, Mark T.; Bhunia, Arun K.

    2005-11-01

    A mammalian cell-based optical biosensor was built to detect pathogenic Listeria and Bacillus species. This sensor measures the ability of the pathogens to infect and induce cytotoxicity on hybrid lymphocyte cell line (Ped-2E9) resulting in the release of alkaline phosphatase (ALP) that can be detected optically using a portable spectrophotometer. The Ped-2E9 cells were encapsulated in collagen gel matrices and grown in 48-well plates or in specially designed filtration tube units. Toxin preparations or bacterial cells were introduced and ALP release was assayed after 3-5 h. Pathogenic L. monocytogenes strains or the listeriolysin toxins preparation showed cytotoxicity ranging from 55% - 92%. Toxin preparations (~20 μg/ml) from B. cereus strains showed 24 - 98% cytotoxicity. In contrast, a non-pathogenic L. innocua (F4247) and a B. substilis induced only 2% and 8% cytotoxicity, respectively. This cell-based detection device demonstrates its ability to detect the presence of pathogenic Listeria and Bacillus species and can potentially be used onsite for food safety or in biosecurity application.

  8. DETECT: a MATLAB toolbox for event detection and identification in time series, with applications to artifact detection in EEG signals.

    Science.gov (United States)

    Lawhern, Vernon; Hairston, W David; Robbins, Kay

    2013-01-01

    Recent advances in sensor and recording technology have allowed scientists to acquire very large time-series datasets. Researchers often analyze these datasets in the context of events, which are intervals of time where the properties of the signal change relative to a baseline signal. We have developed DETECT, a MATLAB toolbox for detecting event time intervals in long, multi-channel time series. Our primary goal is to produce a toolbox that is simple for researchers to use, allowing them to quickly train a model on multiple classes of events, assess the accuracy of the model, and determine how closely the results agree with their own manual identification of events without requiring extensive programming knowledge or machine learning experience. As an illustration, we discuss application of the DETECT toolbox for detecting signal artifacts found in continuous multi-channel EEG recordings and show the functionality of the tools found in the toolbox. We also discuss the application of DETECT for identifying irregular heartbeat waveforms found in electrocardiogram (ECG) data as an additional illustration.

  9. DETECT: a MATLAB toolbox for event detection and identification in time series, with applications to artifact detection in EEG signals.

    Directory of Open Access Journals (Sweden)

    Vernon Lawhern

    Full Text Available Recent advances in sensor and recording technology have allowed scientists to acquire very large time-series datasets. Researchers often analyze these datasets in the context of events, which are intervals of time where the properties of the signal change relative to a baseline signal. We have developed DETECT, a MATLAB toolbox for detecting event time intervals in long, multi-channel time series. Our primary goal is to produce a toolbox that is simple for researchers to use, allowing them to quickly train a model on multiple classes of events, assess the accuracy of the model, and determine how closely the results agree with their own manual identification of events without requiring extensive programming knowledge or machine learning experience. As an illustration, we discuss application of the DETECT toolbox for detecting signal artifacts found in continuous multi-channel EEG recordings and show the functionality of the tools found in the toolbox. We also discuss the application of DETECT for identifying irregular heartbeat waveforms found in electrocardiogram (ECG data as an additional illustration.

  10. Performance evaluation of three automated identification systems in detecting carbapenem-resistant Enterobacteriaceae.

    Science.gov (United States)

    He, Qingwen; Chen, Weiyuan; Huang, Liya; Lin, Qili; Zhang, Jingling; Liu, Rui; Li, Bin

    2016-06-21

    Carbapenem-resistant Enterobacteriaceae (CRE) is prevalent around the world. Rapid and accurate detection of CRE is urgently needed to provide effective treatment. Automated identification systems have been widely used in clinical microbiology laboratories for rapid and high-efficient identification of pathogenic bacteria. However, critical evaluation and comparison are needed to determine the specificity and accuracy of different systems. The aim of this study was to evaluate the performance of three commonly used automated identification systems on the detection of CRE. A total of 81 non-repetitive clinical CRE isolates were collected from August 2011 to August 2012 in a Chinese university hospital, and all the isolates were confirmed to be resistant to carbapenems by the agar dilution method. The potential presence of carbapenemase genotypes of the 81 isolates was detected by PCR and sequencing. Using 81 clinical CRE isolates, we evaluated and compared the performance of three automated identification systems, MicroScan WalkAway 96 Plus, Phoenix 100, and Vitek 2 Compact, which are commonly used in China. To identify CRE, the comparator methodology was agar dilution method, while the PCR and sequencing was the comparator one to identify CPE. PCR and sequencing analysis showed that 48 of the 81 CRE isolates carried carbapenemase genes, including 23 (28.4 %) IMP-4, 14 (17.3 %) IMP-8, 5 (6.2 %) NDM-1, and 8 (9.9 %) KPC-2. Notably, one Klebsiella pneumoniae isolate produced both IMP-4 and NDM-1. One Klebsiella oxytoca isolate produced both KPC-2 and IMP-8. Of the 81 clinical CRE isolates, 56 (69.1 %), 33 (40.7 %) and 77 (95.1 %) were identified as CRE by MicroScan WalkAway 96 Plus, Phoenix 100, and Vitek 2 Compact, respectively. The sensitivities/specificities of MicroScan WalkAway, Phoenix 100 and Vitek 2 were 93.8/42.4 %, 54.2/66.7 %, and 75.0/36.4 %, respectively. The MicroScan WalkAway and Viteck2 systems are more reliable in clinical identification of

  11. Remote sensing techniques for the detection of soil erosion and the identification of soil conservation practices

    Science.gov (United States)

    Pelletier, R. E.; Griffin, R. H.

    1985-01-01

    The following paper is a summary of a number of techniques initiated under the AgRISTARS (Agriculture and Resources Inventory Surveys Through Aerospace Remote Sensing) project for the detection of soil degradation caused by water erosion and the identification of soil conservation practices for resource inventories. Discussed are methods to utilize a geographic information system to determine potential soil erosion through a USLE (Universal Soil Loss Equation) model; application of the Kauth-Thomas Transform to detect present erosional status; and the identification of conservation practices through visual interpretation and a variety of enhancement procedures applied to digital remotely sensed data.

  12. Permeated defect detecting test method and device in reactor

    International Nuclear Information System (INIS)

    Sakurai, Yoshishige.

    1996-01-01

    The present invention provides a method of and a device capable of performing a test for entire inner surfaces of the reactor upon periodical inspection of a BWR type reactor while sufficiently taking countermeasures for radiation rays into consideration. Namely, the present invention comprises following steps. (1) A provisional step for taking a shroud head of a reactor core shroud and incore structural components above and below the shroud out of the reactor, discharging reactor water and water tightly closing openings such as reactor wall perforation holes, (2) a pretreatment step for washing exposed inner surfaces of the reactor and peeling deteriorated materials, (3) a first drying step for drying portions washed and peeled in the step (2), (4) a permeation step for applying a permeation liquid of a defect detecting medium on the exposed inner surfaces of the reactor, (5) a permeation liquid removing step for removing the an excess permeation liquid in the step (4), (6) a second drying step for drying corresponding portions after performing the step (5), and (7) a flaw detecting step for optically observing the corresponding portions after performing the step (6) and detecting flaws. (I.S.)

  13. 10 CFR 32.103 - Schedule D-prototype tests for ice detection devices containing strontium-90.

    Science.gov (United States)

    2010-01-01

    ... water and the strontium-90 shall be considered leakage. (e) Observations. After each of the tests... 10 Energy 1 2010-01-01 2010-01-01 false Schedule D-prototype tests for ice detection devices... § 32.103 Schedule D—prototype tests for ice detection devices containing strontium-90. An applicant for...

  14. Laser radar range and detection performance for MEMS corner cube retroreflector arrays

    Science.gov (United States)

    Grasso, Robert J.; Odhner, Jefferson E.; Stewart, Hamilton; McDaniel, Robert V.

    2004-12-01

    BAE SYSTEMS reports on a program to characterize the performance of MEMS corner cube retroreflector arrays under laser illumination. These arrays have significant military and commercial application in the areas of: 1) target identification; 2) target tracking; 3) target location; 4) identification friend-or-foe (IFF); 5) parcel tracking, and; 6) search and rescue assistance. BAE SYSTEMS has theoretically determined the feasibility of these devices to learn if sufficient signal-to-noise performance exists to permit a cooperative laser radar sensor to be considered for device location and interrogation. Results indicate that modest power-apertures are required to achieve SNR performance consistent with high probability of detection and low false alarm rates.

  15. Detection of Special Operations Forces Using Night Vision Devices

    Energy Technology Data Exchange (ETDEWEB)

    Smith, C.M.

    2001-10-22

    Night vision devices, such image intensifiers and infrared imagers, are readily available to a host of nations, organizations, and individuals through international commerce. Once the trademark of special operations units, these devices are widely advertised to ''turn night into day''. In truth, they cannot accomplish this formidable task, but they do offer impressive enhancement of vision in limited light scenarios through electronically generated images. Image intensifiers and infrared imagers are both electronic devices for enhancing vision in the dark. However, each is based upon a totally different physical phenomenon. Image intensifiers amplify the available light energy whereas infrared imagers detect the thermal energy radiated from all objects. Because of this, each device operates from energy which is present in a different portion of the electromagnetic spectrum. This leads to differences in the ability of each device to detect and/or identify objects. This report is a compilation of the available information on both state-of-the-art image intensifiers and infrared imagers. Image intensifiers developed in the United States, as well as some foreign made image intensifiers, are discussed. Image intensifiers are categorized according to their spectral response and sensitivity using the nomenclature of GEN I, GEN II, and GEN III. As the first generation of image intensifiers, GEN I, were large and of limited performance, this report will deal with only GEN II and GEN III equipment. Infrared imagers are generally categorized according to their spectral response, sensor materials, and related sensor operating temperature using the nomenclature Medium Wavelength Infrared (MWIR) Cooled and Long Wavelength Infrared (LWIR) Uncooled. MWIR Cooled refers to infrared imagers which operate in the 3 to 5 {micro}m wavelength electromagnetic spectral region and require either mechanical or thermoelectric coolers to keep the sensors operating at 77 K

  16. Multi-stage identification scheme for detecting damage in structures under ambient excitations

    International Nuclear Information System (INIS)

    Bao, Chunxiao; Li, Zhong-Xian; Hao, Hong

    2013-01-01

    Structural damage identification methods are critical to the successful application of structural health monitoring (SHM) systems to civil engineering structures. The dynamic response of civil engineering structures is usually characterized by high nonlinearity and non-stationarity. Accordingly, an improved Hilbert–Huang transform (HHT) method which is adaptive, output-only and applicable to system identification of in-service structures under ambient excitations is developed in this study. Based on this method, a multi-stage damage detection scheme including the detection of damage occurrence, damage existence, damage location and the estimation of damage severity is developed. In this scheme, the improved HHT method is used to analyse the structural acceleration response, the obtained instantaneous frequency detects the instant of damage occurrence, the instantaneous phase is sensitive to minor damage and provides reliable damage indication, and the damage indicator developed based on statistical analysis of the Hilbert marginal spectrum detects damage locations. Finally, the response sampled at the detected damage location is continuously analysed to estimate the damage severity. Numerical and experimental studies of frame structures under ambient excitations are performed. The results demonstrate that this scheme accomplishes the above damage detection functions within one flow. It is robust, time efficient, simply implemented and applicable to the real-time SHM of in-service structures. (paper)

  17. A New Algorithm for Radioisotope Identification of Shielded and Masked SNM/RDD Materials

    International Nuclear Information System (INIS)

    Jeffcoat, R.

    2012-01-01

    Detection and identification of shielded and masked nuclear materials is crucial to national security, but vast borders and high volumes of traffic impose stringent requirements for practical detection systems. Such tools must be be mobile, and hence low power, provide a low false alarm rate, and be sufficiently robust to be operable by non-technical personnel. Currently fielded systems have not achieved all of these requirements simultaneously. Transport modeling such as that done in GADRAS is able to predict observed spectra to a high degree of fidelity; our research is focusing on a radionuclide identification algorithm that inverts this modeling within the constraints imposed by a handheld device. Key components of this work include incorporation of uncertainty as a function of both the background radiation estimate and the hypothesized sources, dimensionality reduction, and nonnegative matrix factorization. We have partially evaluated performance of our algorithm on a third-party data collection made with two different sodium iodide detection devices. Initial results indicate, with caveats, that our algorithm performs as good as or better than the on-board identification algorithms. The system developed was based on a probabilistic approach with an improved approach to variance modeling relative to past work. This system was chosen based on technical innovation and system performance over algorithms developed at two competing research institutions. One key outcome of this probabilistic approach was the development of an intuitive measure of confidence which was indeed useful enough that a classification algorithm was developed based around alarming on high confidence targets. This paper will present and discuss results of this novel approach to accurately identifying shielded or masked radioisotopes with radiation detection systems.

  18. 21 CFR 866.5900 - Cystic fibrosis transmembrane conductance regulator (CFTR) gene mutation detection system.

    Science.gov (United States)

    2010-04-01

    ... regulator (CFTR) gene mutation detection system. 866.5900 Section 866.5900 Food and Drugs FOOD AND DRUG...) gene mutation detection system. (a) Identification. The CFTR gene mutation detection system is a device... Guidance Document: CFTR Gene Mutation Detection System.” See § 866.1(e) for the availability of this...

  19. Axis vibration detection device for reactor recycling pump

    International Nuclear Information System (INIS)

    Ide, Katsuki.

    1995-01-01

    The present invention provides a device for detecting, in a contactless manner, vibrations of a recycling pump shaft disposed in a reactor pressure vessel of a BWR type reactor. Namely, the vibration detector comprises an eddy current type displacement gauge having a sensing portion at one end of a linear tube type metal holder. It also comprises a rotational member made of an electroconductive material rotating integrally with a rotational pump shaft. The vibration detector is inserted into an attaching hole passing through a pump casing at a position where the sensing portion faces the outer circumference of the rotational member. The attaching hole is closed by a holder of the oscillation detector and a metal cap integrated to one end of the holder. A high pressure hermetic seal connector is disposed at a position outer side of the attaching hole of the vibration detector for electrically connecting the inside and the outside thereof. The device of the present invention can directly detect the vibration of the pump shaft. As a result, an abnormality, if should occur, in the recycling pump can be found in an early stage. Since the vibration detector is covered with a metal and shielded by the high pressure hermetic seal connector, it can sufficiently ensure pressure resistance. (I.S.)

  20. A portable device for rapid nondestructive detection of fresh meat quality

    Science.gov (United States)

    Lin, Wan; Peng, Yankun

    2014-05-01

    Quality attributes of fresh meat influence nutritional value and consumers' purchasing power. In order to meet the demand of inspection department for portable device, a rapid and nondestructive detection device for fresh meat quality based on ARM (Advanced RISC Machines) processor and VIS/NIR technology was designed. Working principal, hardware composition, software system and functional test were introduced. Hardware system consisted of ARM processing unit, light source unit, detection probe unit, spectral data acquisition unit, LCD (Liquid Crystal Display) touch screen display unit, power unit and the cooling unit. Linux operating system and quality parameters acquisition processing application were designed. This system has realized collecting spectral signal, storing, displaying and processing as integration with the weight of 3.5 kg. 40 pieces of beef were used in experiment to validate the stability and reliability. The results indicated that prediction model developed using PLSR method using SNV as pre-processing method had good performance, with the correlation coefficient of 0.90 and root mean square error of 1.56 for validation set for L*, 0.95 and 1.74 for a*,0.94 and 0.59 for b*, 0.88 and 0.13 for pH, 0.79 and 12.46 for tenderness, 0.89 and 0.91 for water content, respectively. The experimental result shows that this device can be a useful tool for detecting quality of meat.

  1. Implanted cardiac devices are reliably detected by commercially available metal detectors

    DEFF Research Database (Denmark)

    Holm, Katja Fiedler; Hjortshøj, Søren Pihlkjær; Pehrson, Steen

    2013-01-01

    Explosions of Cardiovascular Implantable Electronic Devices (CIEDs) (pacemakers, defibrillators, and loop recorders) are a well-recognized problem during cremation, due to lithium-iodine batteries. In addition, burial of the deceased with a CIED can present a potential risk for environmental...... contamination. Therefore, detection of CIEDs in the deceased would be of value. This study evaluated a commercially available metal detector for detecting CIEDs....

  2. Novel protease-based diagnostic devices for detection of wound infection

    NARCIS (Netherlands)

    Heinzle, A.; Papen-Botterhuis, N.E.; Schiffer, D.; Schneider, K.P.; Binder, B.; Schintler, M.; Haaksman, I.K.; Lenting, H.B.; Gübitz, G.M.; Sigl, E.

    2013-01-01

    A gelatinase-based device for fast detection of wound infection was developed. Collective gelatinolytic activity in infected wounds was 23 times higher (p ≤ 0.001) than in noninfected wounds and blisters according to the clinical and microbiological description of the wounds. Enzyme activities of

  3. Detection, Identification, Location, and Remote Sensing Using SAW RFID Sensor Tags

    Science.gov (United States)

    Barton, Richard J.; Kennedy, Timothy F.; Williams, Robert M.; Fink, Patrick W.; Ngo, Phong H.

    2009-01-01

    The Electromagnetic Systems Branch (EV4) of the Avionic Systems Division at NASA Johnson Space Center in Houston, TX is studying the utility of surface acoustic wave (SAW) radiofrequency identification (RFID) tags for multiple wireless applications including detection, identification, tracking, and remote sensing of objects on the lunar surface, monitoring of environmental test facilities, structural shape and health monitoring, and nondestructive test and evaluation of assets. For all of these applications, it is anticipated that the system utilized to interrogate the SAW RFID tags may need to operate at fairly long range and in the presence of considerable multipath and multiple-access interference. Towards that end, EV4 is developing a prototype SAW RFID wireless interrogation system for use in such environments called the Passive Adaptive RFID Sensor Equipment (PARSED) system. The system utilizes a digitally beam-formed planar receiving antenna array to extend range and provide direction-of-arrival information coupled with an approximate maximum-likelihood signal processing algorithm to provide near-optimal estimation of both range and temperature. The system is capable of forming a large number of beams within the field of view and resolving the information from several tags within each beam. The combination of both spatial and waveform discrimination provides the capability to track and monitor telemetry from a large number of objects appearing simultaneously within the field of view of the receiving array. In this paper, we will consider the application of the PARSEQ system to the problem of simultaneous detection, identification, localization, and temperature estimation for multiple objects. We will summarize the overall design of the PARSEQ system and present a detailed description of the design and performance of the signal detection and estimation algorithms incorporated in the system. The system is currently configured only to measure temperature

  4. A device for the color measurement and detection of spots on the skin

    Science.gov (United States)

    Pladellorens, Josep; Pintó, Agusti; Segura, Jordi; Cadevall, Cristina; Antó, Joan; Pujol, Jaume; Vilaseca, Meritxell; Coll, Joaquín

    2006-08-01

    In this work we present a new and fast easyâ€``to-use device which allows the measurement of color and the detection of spots on the human skin. The developed device is highly practical for relatively untrained operators and uses inexpensive consumer equipment, such as a CCD color camera, a light source composed of LEDs and a laptop. In order to perform these measurements the system takes a picture of the skin. After that, the operator selects the region of the skin to be analyzed on the image displayed and the system provides the CIELAB color coordinates, the chroma and the ITA parameter (Individual Tipology Angle), allowing the comparison with other reference images by means of the CIELAB color differences. The system also detects the spots, such as freckles, age spots, sun spots, pimples, black heads, etc., in a determined region, allowing the objective measurement of their size and area. The knowledge of the color of the skin and the detection of spots can be useful in several areas such as in dermatology applications, the cosmetics industry, the biometrics field, health care etc.

  5. 21 CFR 866.2660 - Microorganism differentiation and identification device.

    Science.gov (United States)

    2010-04-01

    ... HUMAN SERVICES (CONTINUED) MEDICAL DEVICES IMMUNOLOGY AND MICROBIOLOGY DEVICES Microbiology Devices... impregnated with test reagents, that are usually contained in individual compartments and used to...

  6. Colorimetric Sensor Arrays for the Detection and Identification of Chemical Weapons and Explosives.

    Science.gov (United States)

    Kangas, Michael J; Burks, Raychelle M; Atwater, Jordyn; Lukowicz, Rachel M; Williams, Pat; Holmes, Andrea E

    2017-03-04

    There is a significant demand for devices that can rapidly detect chemical-biological-explosive (CBE) threats on-site and allow for immediate responders to mitigate spread, risk, and loss. The key to an effective reconnaissance mission is a unified detection technology that analyzes potential threats in real time. In addition to reviewing the current state of the art in the field, this review illustrates the practicality of colorimetric arrays composed of sensors that change colors in the presence of analytes. This review also describes an outlook toward future technologies, and describes how they could possibly be used in areas such as war zones to detect and identify hazardous substances.

  7. A portable smart-phone device for rapid and sensitive detection of E. coli O157:H7 in Yoghurt and Egg.

    Science.gov (United States)

    Zeinhom, Mohamed Maarouf Ali; Wang, Yijia; Song, Yang; Zhu, Mei-Jun; Lin, Yuehe; Du, Dan

    2018-01-15

    The detection of E. coli O157:H7 in foods has held the attention of many researchers because of the seriousness attributed to this pathogen. In this study, we present a simple, sensitive, rapid and portable smartphone based fluorescence device for E. coli O157:H7 detection. This field-portable fluorescent imager on the smartphone involves a compact laser-diode-based photosource, a long-pass (LP) thin-film interference filter and a high-quality insert lenses. The design of the device provided a low noise to background imaging system. Based on a sandwich ELISA and the specific recognition of antibody to E. coli O157:H7, the sensitive detection of E. coli O157:H7 were realized both in standard samples and real matrix in yoghurt and egg on our device. The detection limit are 1 CFU/mL and 10 CFU/mL correspondingly. Recovery percentages of spiked yogurt and egg samples with 10 3 , 10 4 and 10 5 CFU/mL E. coli O157:H7 were 106.98, 96.52 and 102.65 (in yogurt) and 107.37, 105.64 and 93.84 (in egg) samples using our device, respectively. Most importantly, the entire process could be quickly completed within two hours. This smartphone based device provides a simple, rapid, sensitive detection platform for fluorescent imaging which applied in pathogen detection for food safety monitoring. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. Wearable Vibrotactile Biofeedback Device Allowing Identification of Different Floor Conditions for Lower-Limb Amputees.

    Science.gov (United States)

    Wan, Anson H; Wong, Duo W; Ma, Christina Z; Zhang, Ming; Lee, Winson C

    2016-07-01

    To evaluate a newly developed biofeedback device enabling lower-limb amputees to identify various floor conditions. Self-control with repeated measures (with and without the biofeedback device) within the amputee group, and group control comparing between amputee and nonamputee groups. University locomotion laboratory. Five lower-limb amputees and 8 nonamputees (N=13). A wearable biofeedback device, which identified different floor conditions by analyzing the force patterns under the prosthetic feet and provided vibration cues in response to different floor conditions, was provided to the amputees. The subjects stepped on a foam platform concealing a small object or no object at 1 of the 4 locations of the foot sole. Subjects were asked whether there was a small object under their feet and the location of the object if it existed. The test was repeated with 4 different object types and 4 object locations. The success rate of floor identification was evaluated. Without the biofeedback device, nonamputee subjects (76.56%) identified floor conditions better than amputees (22.5%) significantly (Pdevice, the amputees significantly improved (Pdevice, amputees significantly improved their abilities in identifying different floor conditions. Future attempts could configure the device to allow it to provide warning signals in response to fall-inducing conditions. Copyright © 2016 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  9. Improved sensitivity and limit-of-detection of lateral flow devices using spatial constrictions of the flow-path.

    Science.gov (United States)

    Katis, Ioannis N; He, Peijun J W; Eason, Robert W; Sones, Collin L

    2018-05-03

    We report on the use of a laser-direct write (LDW) technique that allows the fabrication of lateral flow devices with enhanced sensitivity and limit of detection. This manufacturing technique comprises the dispensing of a liquid photopolymer at specific regions of a nitrocellulose membrane and its subsequent photopolymerisation to create impermeable walls inside the volume of the membrane. These polymerised structures are intentionally designed to create fluidic channels which are constricted over a specific length that spans the test zone within which the sample interacts with pre-deposited reagents. Experiments were conducted to show how these constrictions alter the fluid flow rate and the test zone area within the constricted channel geometries. The slower flow rate and smaller test zone area result in the increased sensitivity and lowered limit of detection for these devices. We have quantified these via the improved performance of a C-Reactive Protein (CRP) sandwich assay on our lateral flow devices with constricted flow paths which demonstrate an improvement in its sensitivity by 62x and in its limit of detection by 30x when compared to a standard lateral flow CRP device. Crown Copyright © 2018. Published by Elsevier B.V. All rights reserved.

  10. Detecting exposure to environmental organic toxins in individual cells: towards development of a micro-fabricated device

    International Nuclear Information System (INIS)

    Holman, Hoi-Ying N.; Zhang, Miqin; Goth-Goldstein, Regine; Martin, Michael C.; Russell, Marion; McKinney, Wayne R.; Ferrari, Mauro; Hunter-Cevera, Jennie C.

    1999-01-01

    A new method is being developed to quickly screen for the human exposure potential to polycyclic aromatic hydrocarbons (PAHs) and organochlorines (OCs). The development involves two key elements: identifying suitable signals that represent intracellular changes that are specific to PAH and OC exposure, and constructing a device to guide the biological cell growth so that signals from individual cells are consistent and reproducible. We are completing the identification of suitable signals by using synchrotron radiation-based (SR) Fourier-transform infrared (FTIR) spectromicroscopy in the mid-infrared region (4000-400 cm-1). Distinct changes have been observed in the IR spectra after treatment of human cells in culture medium with PAHs and OCs. The potential use of this method for detecting exposure to PAHs and OCs has been tested and compared to a reverse transcription polymerase chain reaction (RT-PCR) assay that quantifies increased expression of the CYP1A1 gene in response to exposure to PAHs or OCs

  11. Molecular techniques for the identification and detection of microorganisms relevant for the food industry

    NARCIS (Netherlands)

    Klijn, N.

    1996-01-01

    The research described in this thesis concerns the development and application in food microbiology of molecular identification and detection techniques based on 16S rRNA sequences. The technologies developed were applied to study the microbial ecology of two groups of bacteria, namely

  12. Automated systems in the identification and determination of methicillin resistance among coagulase negative staphylococci

    Directory of Open Access Journals (Sweden)

    Juliana Caierão

    2006-05-01

    Full Text Available Coagulase-negative staphylococci (CoNS are an important cause of nosocomial bacteremia, specially in patients with indwelling devices or those submitted to invasive medical procedures. The identification of species and the accurate and rapid detection of methicillin resistance are directly dependent on the quality of the identification and susceptibility tests used, either manual or automated. The objective of this study was to evaluate the accuracy of two automated systems MicroScan and Vitek - in the identification of CoNS species and determination of susceptibility to methicillin, considering as gold standard the biochemical tests and the characterization of the mecA gene by polymerase chain reaction, respectively. MicroScan presented better results in the identification of CoNS species (accuracy of 96.8 vs 78.8%, respectively; isolates from the following species had no precise identification: Staphylococcus haemolyticus, S. simulans, and S. capitis. Both systems were similar in the characterization of methicillin resistance. The higher discrepancies for gene mec detection were observed among species other than S. epidermidis (S. hominis, S. saprophyticus, S. sciuri, S. haemolyticus, S. warneri, S. cohnii, and those with borderline MICs.

  13. Improvement of the Raman detection system for pesticide residues on/in fruits and vegetables

    Science.gov (United States)

    Li, Yan; Peng, Yankun; Zhai, Chen; Chao, Kuanglin; Qin, Jianwei

    2017-05-01

    Pesticide residue is one of the major challenges to fruits safety, while the traditional detection methods of pesticide residue on fruits and vegetables can't afford the demand of rapid detection in actual production because of timeconsuming. Thus rapid identification and detection methods for pesticide residue are urgently needed at present. While most Raman detection systems in the market are spot detection systems, which limits the range of application. In the study, our lab develops a Raman detection system to achieve area-scan thorough the self-developed spot detection Raman system with a control software and two devices. In the system, the scanning area is composed of many scanning spots, which means every spot needs to be detected and more time will be taken than area-scan Raman system. But lower detection limit will be achieved in this method. And some detection device is needed towards fruits and vegetables in different shape. Two detection devices are developed to detect spherical fruits and leaf vegetables. During the detection, the device will make spherical fruit rotate along its axis of symmetry, and leaf vegetables will be pressed in the test surface smoothly. The detection probe will be set to keep a proper distance to the surface of fruits and vegetables. It should make sure the laser shins on the surface of spherical fruit vertically. And two software are used to detect spherical fruits and leaf vegetables will be integrated to one, which make the operator easier to switch. Accordingly two detection devices for spherical fruits and leaf vegetables will also be portable devices to make it easier to change. In the study, a new way is developed to achieve area-scan result by spot-scan Raman detection system.

  14. Leakage detecting method and device for water tight vessel of wet-type container apparatus

    International Nuclear Information System (INIS)

    Tanaka, Yoshimi.

    1995-01-01

    The present invention provides a method of and a device for detecting leakage of a water tight vessel of a wet-type container apparatus for containing a reactor pressure vessel while immersing it water in a reactor container. Namely, in the wet-type container apparatus, the periphery of the pressure vessel is coated with a heat insulation material and the periphery of the heat insulation material is coated with a water tight vessel. The water tight vessel is immersed under water in the reactor container. As a method of detecting leakage of the wet-type container apparatus, gases mixed with helium are supplied into the water tight vessel at a pressure higher than the inner pressure of the reactor container at a lowest position of the reactor pressure vessel. A water level in the reactor container is determined so as to form a space at the top portion of the inside of the reactor container. The helium at the top portion is detected to monitor the leakage of the water tight vessel. With such procedures, even if the water tight vessel is ruptured at any position, helium mixed to the gases is released to water in the reactor container and rise up to the top space and detected by a helium leakage detection device. (I.S.)

  15. Delamination Detection of Reinforced Concrete Decks Using Modal Identification

    Directory of Open Access Journals (Sweden)

    Shutao Xing

    2012-01-01

    Full Text Available This study addressed delamination detection of concrete slabs by analyzing global dynamic responses of structures. Both numerical and experimental studies are presented. In the numerical examples, delaminations with different sizes and locations were introduced into a concrete slab; the effects of presence, sizes, and locations of delaminations on the modal frequencies and mode shapes of the concrete slab under various support conditions were studied. In the experimental study, four concrete deck specimens with different delamination sizes were constructed, and experimental tests were conducted. Traditional peak-picking, frequency domain decomposition, and stochastic subspace identification methods were applied to the modal identification from dynamic response measurements. The modal parameters identified by these three methods correlated well. The changes in modal frequencies, damping ratios, and mode shapes that were extracted from the dynamic measurements were investigated and correlated to the actual delaminations and can indicate presence and severity of delamination. Finite element (FE models of reinforced concrete decks with different delamination sizes and locations were established. The modal parameters computed from the FE models were compared to those obtained from the laboratory specimens, and the FE models were validated. The delamination detection approach was proved to be effective for concrete decks on beams.

  16. Exploiting Multiple Detections for Person Re-Identification

    Directory of Open Access Journals (Sweden)

    Amran Bhuiyan

    2018-01-01

    Full Text Available Re-identification systems aim at recognizing the same individuals in multiple cameras, and one of the most relevant problems is that the appearance of same individual varies across cameras due to illumination and viewpoint changes. This paper proposes the use of cumulative weighted brightness transfer functions (CWBTFs to model these appearance variations. Different from recently proposed methods which only consider pairs of images to learn a brightness transfer function, we exploit such a multiple-frame-based learning approach that leverages consecutive detections of each individual to transfer the appearance. We first present a CWBTF framework for the task of transforming appearance from one camera to another. We then present a re-identification framework where we segment the pedestrian images into meaningful parts and extract features from such parts, as well as from the whole body. Jointly, both of these frameworks contribute to model the appearance variations more robustly. We tested our approach on standard multi-camera surveillance datasets, showing consistent and significant improvements over existing methods on three different datasets without any other additional cost. Our approach is general and can be applied to any appearance-based method.

  17. Improved detection of breast cancer on FDG-PET cancer screening using breast positioning device

    International Nuclear Information System (INIS)

    Kaida, Hayato; Ishibashi, Masatoshi; Fujii, Teruhiko; Kurata, Seiji; Ogo, Etsuyo; Hayabuchi, Naofumi; Tanaka, Maki

    2008-01-01

    The aim of this study was to investigate the detection rate of breast cancer by positron emission tomography cancer screening using a breast positioning device. Between January 2004 and January 2006, 1,498 healthy asymptomatic individuals underwent cancer screening by fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) at our institution; 660 of 1498 asymptomatic healthy women underwent breast PET imaging in the prone position using the breast positioning device to examine the mammary glands in addition to whole-body PET imaging. All subjects that showed abnormal 18 F-FDG uptake in the mammary glands were referred for further examination or surgery at our institution or a local hospital. Our data were compared with the histopathological findings or findings of other imaging modalities in our institution and replies from the doctors at another hospital. Of the 660 participants, 7 (1.06%) were found to have breast cancers at a curable stage. All the seven cancers were detected by breast PET imaging, but only five of these were detected by whole-body PET imaging; the other two were detected by breast PET imaging using the breast positioning device. In cancer screening, prone breast imaging using a positioning device may help to improve the detection rate of breast cancer. However, overall cancer including mammography and ultrasonography screening should be performed to investigate the false-negative cases and reduce false-positive cases. The effectiveness of prone breast PET imaging in cancer screening should be investigated using a much larger number of cases in the near future. (author)

  18. A System of Driving Fatigue Detection Based on Machine Vision and Its Application on Smart Device

    Directory of Open Access Journals (Sweden)

    Wanzeng Kong

    2015-01-01

    Full Text Available Driving fatigue is one of the most important factors in traffic accidents. In this paper, we proposed an improved strategy and practical system to detect driving fatigue based on machine vision and Adaboost algorithm. Kinds of face and eye classifiers are well trained by Adaboost algorithm in advance. The proposed strategy firstly detects face efficiently by classifiers of front face and deflected face. Then, candidate region of eye is determined according to geometric distribution of facial organs. Finally, trained classifiers of open eyes and closed eyes are used to detect eyes in the candidate region quickly and accurately. The indexes which consist of PERCLOS and duration of closed-state are extracted in video frames real time. Moreover, the system is transplanted into smart device, that is, smartphone or tablet, due to its own camera and powerful calculation performance. Practical tests demonstrated that the proposed system can detect driver fatigue with real time and high accuracy. As the system has been planted into portable smart device, it could be widely used for driving fatigue detection in daily life.

  19. Identification and Damage Detection on Structural Systems

    DEFF Research Database (Denmark)

    Brincker, Rune; Kirkegaard, Poul Henning; Andersen, Palle

    1994-01-01

    A short introduction is given to system identification and damage assessment in civil engineering structures. The most commonly used FFT-based techniques for system identification are mentioned, and the Random decrement technique and parametric methods based on ARMA models are introduced. Speed...

  20. Utilization of photoconductive gain in a-Si:H devices for radiation detection

    International Nuclear Information System (INIS)

    Lee, H.K.; Drewery, J.S.; Hong, W.S.; Jing, T.; Kaplan, S.N.; Perez-Mendez, V.

    1995-05-01

    The photoconductive gain mechanism in a-Si:H was investigated in connection with applications to radiation detection. Various device types such as p-i-n, n-i-n and n-i-p-i-n structures were fabricated and tested. Photoconductive gain was measured in two time scales: one for short pulses of visible light ( 2 . Various gain results are discussed in terms of the device structure, applied bias and dark current

  1. A unique charge-coupled device/xenon arc lamp based imaging system for the accurate detection and quantitation of multicolour fluorescence.

    Science.gov (United States)

    Spibey, C A; Jackson, P; Herick, K

    2001-03-01

    In recent years the use of fluorescent dyes in biological applications has dramatically increased. The continual improvement in the capabilities of these fluorescent dyes demands increasingly sensitive detection systems that provide accurate quantitation over a wide linear dynamic range. In the field of proteomics, the detection, quantitation and identification of very low abundance proteins are of extreme importance in understanding cellular processes. Therefore, the instrumentation used to acquire an image of such samples, for spot picking and identification by mass spectrometry, must be sensitive enough to be able, not only, to maximise the sensitivity and dynamic range of the staining dyes but, as importantly, adapt to the ever changing portfolio of fluorescent dyes as they become available. Just as the available fluorescent probes are improving and evolving so are the users application requirements. Therefore, the instrumentation chosen must be flexible to address and adapt to those changing needs. As a result, a highly competitive market for the supply and production of such dyes and the instrumentation for their detection and quantitation have emerged. The instrumentation currently available is based on either laser/photomultiplier tube (PMT) scanning or lamp/charge-coupled device (CCD) based mechanisms. This review briefly discusses the advantages and disadvantages of both System types for fluorescence imaging, gives a technical overview of CCD technology and describes in detail a unique xenon/are lamp CCD based instrument, from PerkinElmer Life Sciences. The Wallac-1442 ARTHUR is unique in its ability to scan both large areas at high resolution and give accurate selectable excitation over the whole of the UV/visible range. It operates by filtering both the excitation and emission wavelengths, providing optimal and accurate measurement and quantitation of virtually any available dye and allows excellent spectral resolution between different fluorophores

  2. Medical isotope identification with large mobile detection systems

    Science.gov (United States)

    Mukhopadhyay, Sanjoy; Maurer, Richard

    2012-10-01

    The Remote Sensing laboratory (RSL) of National Security Technologies Inc. has built an array of large (5.08 - cm x 10.16 - cm x 40.6 - cm) thallium doped sodium iodide (NaI: Tl) scintillators to locate and screen gamma-ray emitting radioisotopes that are of interests to radiological emergency responders [1]. These vehicle mounted detectors provide the operators with rapid, simple, specific information for radiological threat assessment. Applications include large area inspection, customs inspection, border protection, emergency response, and monitoring of radiological facilities. These RSL mobile units are currently being upgraded to meet the Defense Threat Reduction Agency mission requirements for a next-generation system capable of detecting and identifying nuclear threat materials. One of the challenging problems faced by these gamma-ray detectors is the unambiguous identification of medical isotopes like 131I (364.49 keV [81.7%], 636.99 keV [7.17%]), 99Tcm (140.51 keV [89.1%]) and 67Ga (184.6 keV [19.7%], 300.2 [16.0%], 393.5 [4.5%] that are used in radionuclide therapy and often have overlapping gamma-ray energy regions of interest (ROI). The problem is made worse by short (about 5 seconds) acquisition time of the spectral data necessary for dynamic mobile detectors. This article describes attempts to identify medical isotopes from data collected from this mobile detection system in a short period of time (not exceeding 5 secs) and a large standoff distance (typically 10 meters) The mobile units offer identification capabilities that are based on hardware auto stabilization of the amplifier gain. The 1461 keV gamma-energy line from 40K is tracked. It uses gamma-ray energy windowing along with embedded mobile Gamma Detector Response and Analysis Software (GADRAS) [2] simultaneously to deconvolve any overlapping gamma-energy ROIs. These high sensitivity detectors are capable of resolving complex masking scenarios and exceed all ANSI N42.34 (2006) requirements

  3. Device for detecting imminent failure of high-dielectric stress capacitors. [Patent application

    Science.gov (United States)

    McDuff, G.G.

    1980-11-05

    A device is described for detecting imminent failure of a high-dielectric stress capacitor utilizing circuitry for detecting pulse width variations and pulse magnitude variations. Inexpensive microprocessor circuitry is utilized to make numerical calculations of digital data supplied by detection circuitry for comparison of pulse width data and magnitude data to determine if preselected ranges have been exceeded, thereby indicating imminent failure of a capacitor. Detection circuitry may be incorporated in transmission lines, pulse power circuitry, including laser pulse circuitry or any circuitry where capacitors or capacitor banks are utilized.

  4. New application of (ΔE-E) technique for particle identification and dosimetry

    International Nuclear Information System (INIS)

    Mineev, Yu.V.

    1998-01-01

    The modified method of charged particle identification is described. It is based on the simultaneous measurement of the energy E and the specific losses ΔE with the application of semiconductor detectors as well as programmed semiconductor memory devices for the storage of the preset calculated dependence ΔE(E) for each particle kinds. The comparison of expected and measured values ΔE at the measured energy value E defines completely the particle kind. New possibilities of the method for identification as well as separate and simultaneous detection of different particles (electrons, protons, alpha-particles, nuclei with Z ≤ 12 and gamma-radiation) are analyzed

  5. Patient identification errors: the detective in the laboratory.

    Science.gov (United States)

    Salinas, Maria; López-Garrigós, Maite; Lillo, Rosa; Gutiérrez, Mercedes; Lugo, Javier; Leiva-Salinas, Carlos

    2013-11-01

    The eradication of errors regarding patients' identification is one of the main goals for safety improvement. As clinical laboratory intervenes in 70% of clinical decisions, laboratory safety is crucial in patient safety. We studied the number of Laboratory Information System (LIS) demographic data errors registered in our laboratory during one year. The laboratory attends a variety of inpatients and outpatients. The demographic data of outpatients is registered in the LIS, when they present to the laboratory front desk. The requests from the primary care centers (PCC) are made electronically by the general practitioner. A manual step is always done at the PCC to conciliate the patient identification number in the electronic request with the one in the LIS. Manual registration is done through hospital information system demographic data capture when patient's medical record number is registered in LIS. Laboratory report is always sent out electronically to the patient's electronic medical record. Daily, every demographic data in LIS is manually compared to the request form to detect potential errors. Fewer errors were committed when electronic order was used. There was great error variability between PCC when using the electronic order. LIS demographic data manual registration errors depended on patient origin and test requesting method. Even when using the electronic approach, errors were detected. There was a great variability between PCC even when using this electronic modality; this suggests that the number of errors is still dependent on the personnel in charge of the technology. © 2013.

  6. Characterization of a direct detection device imaging camera for transmission electron microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Milazzo, Anna-Clare, E-mail: amilazzo@ncmir.ucsd.edu [University of California at San Diego, 9500 Gilman Dr., La Jolla, CA 92093 (United States); Moldovan, Grigore [Department of Materials, University of Oxford, Parks Road, Oxford OX1 3PH (United Kingdom); Lanman, Jason [Department of Molecular Biology, The Scripps Research Institute, La Jolla, CA 92037 (United States); Jin, Liang; Bouwer, James C. [University of California at San Diego, 9500 Gilman Dr., La Jolla, CA 92093 (United States); Klienfelder, Stuart [University of California at Irvine, Irvine, CA 92697 (United States); Peltier, Steven T.; Ellisman, Mark H. [University of California at San Diego, 9500 Gilman Dr., La Jolla, CA 92093 (United States); Kirkland, Angus I. [Department of Materials, University of Oxford, Parks Road, Oxford OX1 3PH (United Kingdom); Xuong, Nguyen-Huu [University of California at San Diego, 9500 Gilman Dr., La Jolla, CA 92093 (United States)

    2010-06-15

    The complete characterization of a novel direct detection device (DDD) camera for transmission electron microscopy is reported, for the first time at primary electron energies of 120 and 200 keV. Unlike a standard charge coupled device (CCD) camera, this device does not require a scintillator. The DDD transfers signal up to 65 lines/mm providing the basis for a high-performance platform for a new generation of wide field-of-view high-resolution cameras. An image of a thin section of virus particles is presented to illustrate the substantially improved performance of this sensor over current indirectly coupled CCD cameras.

  7. Characterization of a direct detection device imaging camera for transmission electron microscopy

    International Nuclear Information System (INIS)

    Milazzo, Anna-Clare; Moldovan, Grigore; Lanman, Jason; Jin, Liang; Bouwer, James C.; Klienfelder, Stuart; Peltier, Steven T.; Ellisman, Mark H.; Kirkland, Angus I.; Xuong, Nguyen-Huu

    2010-01-01

    The complete characterization of a novel direct detection device (DDD) camera for transmission electron microscopy is reported, for the first time at primary electron energies of 120 and 200 keV. Unlike a standard charge coupled device (CCD) camera, this device does not require a scintillator. The DDD transfers signal up to 65 lines/mm providing the basis for a high-performance platform for a new generation of wide field-of-view high-resolution cameras. An image of a thin section of virus particles is presented to illustrate the substantially improved performance of this sensor over current indirectly coupled CCD cameras.

  8. Rapid Detection of Salmonella enterica in Food Using a Compact Disc-Shaped Device

    Directory of Open Access Journals (Sweden)

    Shunsuke Furutani

    2016-01-01

    Full Text Available Rapid detection of food-borne pathogens is essential to public health and the food industry. Although the conventional culture method is highly sensitive, it takes at least a few days to detect food-borne pathogens. Even though polymerase chain reaction (PCR can detect food-borne pathogens in a few hours, it is more expensive and unsatisfactorily sensitive relative to the culture method. We have developed a method to rapidly detect Salmonella enterica by using a compact disc (CD-shaped device that can reduce reagent consumption in conventional PCR. The detection method, which combines culture and PCR, is more rapid than the conventional culture method and is more sensitive and cheaper than PCR. In this study, we also examined a sample preparation method that involved collecting bacterial cells from food. The bacteria collected from chicken meat spiked with S. enterica were mixed with PCR reagents, and PCR was performed on the device. At a low concentration of S. enterica, the collected S. enterica was cultured before PCR for sensitive detection. After cultivation for 4 h, S. enterica at 1.7 × 104 colony-forming units (CFUs·g−1 was detected within 8 h, which included the time needed for sample preparation and detection. Furthermore, the detection of 30 CFUs·g−1 of S. enterica was possible within 12 h including 8 h for cultivation.

  9. Design, building and evaluation of a neutron detection device based on boron loaded plastic scintillator

    International Nuclear Information System (INIS)

    Normand, St.

    2001-10-01

    This work focuses on the study, the characterization and the fabrication of Boron-loaded plastic scintillators. Their use in thermal and fast neutron detection devices is also investigated. Fabrication process, especially boron doping, is explained in the first part of this work. Several FTIR, UV-visible and NMR analysis methods were used in order to characterize the material and to check its structure and stoichiometry. Experiences were done using alpha particles and proton beams to measure the scintillation characteristics. Light emission could therefore be completely determined by the Birks semi-empirical relation. In the second part, the whole detector simulation is undergone: interaction between material and radiation, light generation, paths and signal generation. Neutron simulation by MCNP (Monte Carlo N-Particles) is coupled to a light generation and propagation code developed especially during this work. These simulation tools allow us to optimize the detector geometry for neutron detection and to determine the geometry influence to the photon collection efficiency. Neutron detection efficiency and mean lifetime in this scintillator are also simulated. The close fit obtained between experimental measurements and simulations demonstrate the reliability of the method used. The third part deals with the discrimination methods between neutron and gamma, such as analog (zero crossing) and digital (charge comparison) ones. Their performances were explained and compared. The last part of this work reports on few applications where neutron detection is essential and can be improved with the use of boron loaded plastic scintillators. In particular, the cases of doped scintillation fibers, neutron spectrometry devices and more over neutron multiplicity counting devices are presented. (author)

  10. Single photon detection and localization accuracy with an ebCMOS camera

    Energy Technology Data Exchange (ETDEWEB)

    Cajgfinger, T. [CNRS/IN2P3, Institut de Physique Nucléaire de Lyon, Villeurbanne F-69622 (France); Dominjon, A., E-mail: agnes.dominjon@nao.ac.jp [Université de Lyon, Université de Lyon 1, Lyon 69003 France. (France); Barbier, R. [CNRS/IN2P3, Institut de Physique Nucléaire de Lyon, Villeurbanne F-69622 (France); Université de Lyon, Université de Lyon 1, Lyon 69003 France. (France)

    2015-07-01

    The CMOS sensor technologies evolve very fast and offer today very promising solutions to existing issues facing by imaging camera systems. CMOS sensors are very attractive for fast and sensitive imaging thanks to their low pixel noise (1e-) and their possibility of backside illumination. The ebCMOS group of IPNL has produced a camera system dedicated to Low Light Level detection and based on a 640 kPixels ebCMOS with its acquisition system. After reminding the principle of detection of an ebCMOS and the characteristics of our prototype, we confront our camera to other imaging systems. We compare the identification efficiency and the localization accuracy of a point source by four different photo-detection devices: the scientific CMOS (sCMOS), the Charge Coupled Device (CDD), the Electron Multiplying CCD (emCCD) and the Electron Bombarded CMOS (ebCMOS). Our ebCMOS camera is able to identify a single photon source in less than 10 ms with a localization accuracy better than 1 µm. We report as well efficiency measurement and the false positive identification of the ebCMOS camera by identifying more than hundreds of single photon sources in parallel. About 700 spots are identified with a detection efficiency higher than 90% and a false positive percentage lower than 5. With these measurements, we show that our target tracking algorithm can be implemented in real time at 500 frames per second under a photon flux of the order of 8000 photons per frame. These results demonstrate that the ebCMOS camera concept with its single photon detection and target tracking algorithm is one of the best devices for low light and fast applications such as bioluminescence imaging, quantum dots tracking or adaptive optics.

  11. Vibrotactile Detection, Identification and Directional Perception of signal-Processed Sounds from Environmental Events: A Pilot Field Evaluation in Five Cases

    Directory of Open Access Journals (Sweden)

    Parivash Ranjbar

    2008-09-01

    Full Text Available Objectives: Conducting field tests of a vibrotactile aid for deaf/deafblind persons for detection, identification and directional perception of environmental sounds. Methods: Five deaf (3F/2M, 22–36 years individuals tested the aid separately in a home environment (kitchen and in a traffic environment. Their eyes were blindfolded and they wore a headband and holding a vibrator for sound identification. In the headband, three microphones were mounted and two vibrators for signalling direction of the sound source. The sounds originated from events typical for the home environment and traffic. The subjects were inexperienced (events unknown and experienced (events known. They identified the events in a home and traffic environment, but perceived sound source direction only in traffic. Results: The detection scores were higher than 98% both in the home and in the traffic environment. In the home environment, identification scores varied between 25%-58% when the subjects were inexperienced and between 33%-83% when they were experienced. In traffic, identification scores varied between 20%-40% when the subjects were inexperienced and between 22%-56% when they were experienced. The directional perception scores varied between 30%-60% when inexperienced and between 61%-83% when experienced. Discussion: The vibratory aid consistently improved all participants’ detection, identification and directional perception ability.

  12. Filtering technique for detection and identification of measurement failures in nuclear power plants

    International Nuclear Information System (INIS)

    Racz, A.

    1989-11-01

    The basic requirement of the safe operation of nuclear power plants (NPP) is to have reliable information on all quantities that can be measured, monitored or controlled during the operation. Kalman filtering techniques have been applied for prompt detection and identification of failures in the measurement systems used in NPPs. Mathematical basis of Kalman filtering and various models applied to failure detection are overviewed. The applicability of some models are evaluated by real results of NPP measurements. A sample system for an NPP is suggested, based on several numerical tests. (R.P.) 23 refs.; 40 figs.; 2 tabs

  13. Chemical detection with nano/bio hybrid devices based on carbon nanotubes and graphene

    Science.gov (United States)

    Lerner, Mitchell Bryant

    Carbon nanotube field-effect transistors (NT-FETs) and graphene field effect transistors (GFETs) provide a unique transduction platform for chemical and biomolecular detection. The work presented in this thesis describes the fabrication, characterization, and investigation of operational mechanisms of carbon-based biosensors. In the first set of experiments, we used carbon nanotubes as fast, all-electronic readout elements in novel vapor sensors, suitable for applications in environmental monitoring and medicine. Molecules bound to the hybrid alter the electrical properties of the NT-FET via several mechanisms, allowing direct detection as a change in the transistor conduction properties. Vapor sensors suitable for more complex system architectures characteristic of mammalian olfaction were demonstrated using NT-FETs functionalized with mouse olfactory receptor (mOR) proteins or single stranded DNA (ssDNA). Substitution of graphene as the channel material enabled production of hundreds of electronically similar devices with high yield. Etching large scale chemical vapor deposition (CVD)-grown graphene into small channels is itself a challenging problem, and we have developed novel fabrication methods to this end without sacrificing the inherent electrical quality that makes graphene such an attractive material. Large arrays of such devices have potential utility for understanding the physics of ligand-receptor interactions and contributing to the development of a new generation of devices for electronic olfaction. Tailored and specific detection was accomplished by chemically functionalizing the NT-FET or GFET with biomolecules, such as proteins or small molecules, to create a hybrid nanostructures. Targets for detection were widely varied, indicating the utility of these techniques, such as 1) live Salmonella cells in nutrient broth, 2) a biomarker protein indicative of prostate cancer, 3) antigen protein from the bacterium that causes Lyme disease, and 4) glucose

  14. Reliability of recordings of subgingival calculus detected using an ultrasonic device.

    Science.gov (United States)

    Corraini, Priscila; López, Rodrigo

    2015-04-01

    To assess the intra-examiner reliability of recordings of subgingival calculus detected using an ultrasonic device, and to investigate the influence of subject-, tooth- and site-level factors on the reliability of these subgingival calculus recordings. On two occasions, within a 1-week interval, 147 adult periodontitis patients received a full-mouth clinical periodontal examination by a single trained examiner. Duplicate subgingival calculus recordings, in six sites per tooth, were obtained using an ultrasonic device for calculus detection and removal. Agreement was observed in 65 % of the 22,584 duplicate subgingival calculus recordings, ranging 45 % to 83 % according to subject. Using hierarchical modeling, disagreements in the subgingival calculus duplicate recordings were more likely in all other sites than the mid-buccal, and in sites harboring supragingival calculus. Disagreements were less likely in sites with PD ≥  4 mm and with furcation involvement  ≥  degree 2. Bleeding on probing or suppuration did not influence the reliability of subgingival calculus. At the subject-level, disagreements were less likely in patients presenting with the highest and lowest extent categories of the covariate subgingival calculus. The reliability of subgingival calculus recordings using the ultrasound technology is reasonable. The results of the present study suggest that the reliability of subgingival calculus recordings is not influenced by the presence of inflammation. Moreover, subgingival calculus can be more reliably detected using the ultrasound device at sites with higher need for periodontal therapy, i.e., sites presenting with deep pockets and premolars and molars with furcation involvement.

  15. Detecting device of atomic probe

    International Nuclear Information System (INIS)

    Nikonenkov, N.V.

    1979-01-01

    Operation of an atomic-probe recording device is discussed in detail and its flowsheet is given. The basic elements of the atomic-probe recording device intented for microanalysis of metals and alloys in an atomic level are the storage oscillograph with a raster-sweep unit, a two-channel timer using frequency meters, a digital printer, and a control unit. The digital printer records information supplied by four digital devices (two frequency meters and two digital voltmeters) in a four-digit binary-decimal code. The described device provides simultaneous recording of two ions produced per one vaporation event

  16. Warnings to Counter Choice Blindness for Identification Decisions: Warnings Offer an Advantage in Time but Not in Rate of Detection

    Directory of Open Access Journals (Sweden)

    Anna Sagana

    2018-06-01

    Full Text Available Choice blindness for identification decisions refers to the inability of eyewitnesses to detect that an originally recognized target was swapped for a non-identified lineup member. The robustness of the effect calls for measures that can prevent or reduce the negative consequences of choice blindness manipulations. Here, we investigated whether pre- and post-warnings given to participants about the possibility of mistakes reduces choice blindness for identification decisions. Participants (N = 119 were presented with identifications they never made and were asked to justify those decisions. Either before or after the presentation of the manipulated identification outcome, participants were or were not warned about the possibility of mistakes in the identification process. Although warnings were not sufficient to reduce choice blindness for identification decisions they provided a time-related detection advantage. Pre-warned participants questioned the legitimacy of the manipulated outcome sooner (i.e., concurrent detection than participants in other conditions. Hence, pre-warnings can help detect mistakes in the identification procedure at an earlier stage, before they contaminate the memory of the witness and other pieces of evidence. From a theoretical stance, our findings attest to the strength of self-suggestion and indicate that choice blindness effects are deeply rooted in cognition.

  17. Device for electrochemical detection of metal sample surface resistance and passivation against corrosion in electrolyte

    International Nuclear Information System (INIS)

    Urbancik, L.; Bar, J.; Nemec, J.; Sima, A.

    1986-01-01

    The device consists of a teflon vessel with sealing and an opening below the electrolyte level. Into it is submerged an electrode connected to a dc voltage supply whose other pole is connected to a sample of the metal which is pressed to the opening in the sealing with a flexible strap. The teflon vessel and the sealing are integral. The device is simpler and less costly than those manufactured so far. The operating capability of damaged sealing may be renewed by simple mechanical working. The device may be used for detecting the resistance and passivation of steam generator metal tubes. (J.B.). 1 fig

  18. 21 CFR 866.2580 - Gas-generating device.

    Science.gov (United States)

    2010-04-01

    ...) MEDICAL DEVICES IMMUNOLOGY AND MICROBIOLOGY DEVICES Microbiology Devices § 866.2580 Gas-generating device. (a) Identification. A gas-generating device is a device intended for medical purposes that produces...

  19. Incore instrumentation device

    International Nuclear Information System (INIS)

    Fujita, Kazuhiko.

    1996-01-01

    A position of a detector is detected by a driving device, and the detected values are sampled by a newly disposed central processing unit for sampling the detected values depending on the sampling position of the detected values. Since the sampling position of the detected values is detected by the driving device, the sampling position for the detection values does not rely on the speed of the driving motor of the driving device. The load on the central processing device for controlling the device is lowered by newly disposing the central processing unit for sampling detected values. When the values for the position of the detector counted after conversion to digital values reach the digital values corresponding to the detection value sampling position outputted from the central processing unit for controlling the device, a counted value comparison circuit causes the central processing unit for controlling the device to sample the detection values outputted from the detector. Then, the processing speed can be increased without interruption processings, which can save the central processing unit for sampling detection values. In addition, software can be simplified and loads can be lowered. (N.H.)

  20. Efficient Device-Independent Entanglement Detection for Multipartite Systems

    Science.gov (United States)

    Baccari, F.; Cavalcanti, D.; Wittek, P.; Acín, A.

    2017-04-01

    Entanglement is one of the most studied properties of quantum mechanics for its application in quantum information protocols. Nevertheless, detecting the presence of entanglement in large multipartite states continues to be a great challenge both from the theoretical and the experimental point of view. Most of the known methods either have computational costs that scale inefficiently with the number of particles or require more information on the state than what is attainable in everyday experiments. We introduce a new technique for entanglement detection that provides several important advantages in these respects. First, it scales efficiently with the number of particles, thus allowing for application to systems composed by up to few tens of particles. Second, it needs only the knowledge of a subset of all possible measurements on the state, therefore being apt for experimental implementation. Moreover, since it is based on the detection of nonlocality, our method is device independent. We report several examples of its implementation for well-known multipartite states, showing that the introduced technique has a promising range of applications.

  1. RADIO FREQUENCY IDENTIFICATION DEVICES: EFFECTIVENESS IN IMPROVING SAFEGUARDS AT GAS-CENTRIFUGE URANIUM-ENRICHMENT PLANTS

    International Nuclear Information System (INIS)

    JOE, J.

    2007-01-01

    Recent advances in radio frequency identification devices (RFIDs) have engendered a growing interest among international safeguards experts. Potentially, RFIDs could reduce inspection work, viz. the number of inspections, number of samples, and duration of the visits, and thus improve the efficiency and effectiveness of international safeguards. This study systematically examined the applications of RFIDs for IAEA safeguards at large gas-centrifuge enrichment plants (GCEPs). These analyses are expected to help identify the requirements and desirable properties for RFIDs, to provide insights into which vulnerabilities matter most, and help formulate the required assurance tests. This work, specifically assesses the application of RFIDs for the ''Option 4'' safeguards approach, proposed by Bruce Moran, U. S. Nuclear Regulatory Commission (NRC), for large gas-centrifuge uranium-enrichment plants. The features of ''Option 4'' safeguards include placing RFIDs on all feed, product and tails (F/P/T) cylinders, along with WID readers in all FP/T stations and accountability scales. Other features of Moran's ''Option 4'' are Mailbox declarations, monitoring of load-cell-based weighing systems at the F/P/T stations and accountability scales, and continuous enrichment monitors. Relevant diversion paths were explored to evaluate how RFIDs improve the efficiency and effectiveness of safeguards. Additionally, the analysis addresses the use of RFIDs in conjunction with video monitoring and neutron detectors in a perimeter-monitoring approach to show that RFIDs can help to detect unidentified cylinders

  2. Fault detection and identification in missile system guidance and control: a filtering approach

    Science.gov (United States)

    Padgett, Mary Lou; Evers, Johnny; Karplus, Walter J.

    1996-03-01

    Real-world applications of computational intelligence can enhance the fault detection and identification capabilities of a missile guidance and control system. A simulation of a bank-to- turn missile demonstrates that actuator failure may cause the missile to roll and miss the target. Failure of one fin actuator can be detected using a filter and depicting the filter output as fuzzy numbers. The properties and limitations of artificial neural networks fed by these fuzzy numbers are explored. A suite of networks is constructed to (1) detect a fault and (2) determine which fin (if any) failed. Both the zero order moment term and the fin rate term show changes during actuator failure. Simulations address the following questions: (1) How bad does the actuator failure have to be for detection to occur, (2) How bad does the actuator failure have to be for fault detection and isolation to occur, (3) are both zero order moment and fine rate terms needed. A suite of target trajectories are simulated, and properties and limitations of the approach reported. In some cases, detection of the failed actuator occurs within 0.1 second, and isolation of the failure occurs 0.1 after that. Suggestions for further research are offered.

  3. Universal Detection and Identification of Avian Influenza Virus by Use of Resequencing Microarrays

    Science.gov (United States)

    2009-04-01

    Recent outbreaks of Nipah virus , severe acute respiratory syndrome virus , and avian influenza virus reiterate the impor- tance of zoonotic microbes as...Society for Microbiology. All Rights Reserved. Universal Detection and Identification of Avian Influenza Virus by Use of Resequencing Microarrays...been, and continue to emerge as, threats to human health. The recent outbreaks of highly pathogenic avian influenza virus in bird populations and the

  4. Instrumentation measurement and testing complex for detection and identification of radioactive materials using the emitted radiation

    International Nuclear Information System (INIS)

    Samossadny, V.T.; Dmitrenko, V.V.; Kadlin, V.V.; Kolesnikov, S.V.; Ulin, S.E.; Grachev, V.M.; Vlasik, K.F.; Dedenko, G.L.; Novikov, D.V.; Uteshev, Z.M.

    2006-01-01

    Simultaneous measurement of neutron and gamma radiation is a very usefull method for effective nuclear materials identification and control. The gamma-ray-neutron complex described in the paper is based on two multi-layer 3 He neutrons detectors and two High Pressure Xenon gamma-ray spectrometers assembled in one unit. All these detectors were callibrated on neutron and gamma-ray sources. The main characteristics of the instrumentation , its testing results and gamma-ray and neutron radiation parameters, which have been measured are represented in the paper. The gamma-neutron sources and fissile materials reliable detection and identification capability was demonstrated

  5. Radiation detection device

    International Nuclear Information System (INIS)

    Peschmann, Kristian.

    1982-01-01

    A radiation detector suitable for use in computer tomography device has an ionization chamber which comprises a high voltage electrode, a collector electrode, a high voltage source having two terminals, one connected to the high voltage electrode, current measuring means having two terminals, one connected to the high voltage source and the other to the collector electrode, and an auxilliary electrode near and parallel to the entrance window of the device, having one adjacent to the high voltage electrode and the other adjacent but not connected to the collector electrode. The auxilliary electrode is connected to the high voltage source. In this way the electric field between the high voltage and collector electrodes is made homogeneous in the vicinity of the auxilliary electrode, improving the measuring speed of the detector

  6. Heavy ion elastic recoil detection analysis of optoelectronic and semiconductor devices

    Energy Technology Data Exchange (ETDEWEB)

    Dytlewski, N.; Cohen, D.D. [Australian Nuclear Science and Technology Organisation, Lucas Heights, NSW (Australia); Johnston, P.; Walker, S. [Royal Melbourne Inst. of Tech., VIC (Australia); Whitlow, H.; Hult, M. [Lund Univ. (Sweden); Oestling, M.; Zaring, C. [Royal Inst. of Tech., Stockholm (Sweden)

    1993-12-31

    In recent years, the use of heavy ion time-of-flight elastic recoil spectrometry (HIERDA) has been applied to analyse multi-phase, thin layer devices used in optoelectronics, semiconductors and solar power generation. HIERDA gives simultaneously, mass resolved elemental concentration vs depth profiles of the matrix constituents, and is particularly suited to the determination of light elements in a heavy matrix. The beam/target interaction process is similar to RBS, but has the difference that the recoiling target atoms are detected instead of the scattered projectile. High energy, heavy ions beams bombard the sample, ejecting recoil atoms which are detected at a forward angle of 45 deg. A time-of-flight and total energy detection system enables the ejected particle`s mass to be identified, and allows energy spectra to be obtained and interpreted in an analogous way to RBS, but with the important difference that the elemental spectra are separated, and not superimposed on a background as in RBS. Some of the measurements made with a HIERDA system on the ANTARES Tandem Accelerator at ANSTO are described. 1 refs., 4 figs.

  7. Heavy ion elastic recoil detection analysis of optoelectronic and semiconductor devices

    Energy Technology Data Exchange (ETDEWEB)

    Dytlewski, N; Cohen, D D [Australian Nuclear Science and Technology Organisation, Lucas Heights, NSW (Australia); Johnston, P; Walker, S [Royal Melbourne Inst. of Tech., VIC (Australia); Whitlow, H; Hult, M [Lund Univ. (Sweden); Oestling, M; Zaring, C [Royal Inst. of Tech., Stockholm (Sweden)

    1994-12-31

    In recent years, the use of heavy ion time-of-flight elastic recoil spectrometry (HIERDA) has been applied to analyse multi-phase, thin layer devices used in optoelectronics, semiconductors and solar power generation. HIERDA gives simultaneously, mass resolved elemental concentration vs depth profiles of the matrix constituents, and is particularly suited to the determination of light elements in a heavy matrix. The beam/target interaction process is similar to RBS, but has the difference that the recoiling target atoms are detected instead of the scattered projectile. High energy, heavy ions beams bombard the sample, ejecting recoil atoms which are detected at a forward angle of 45 deg. A time-of-flight and total energy detection system enables the ejected particle`s mass to be identified, and allows energy spectra to be obtained and interpreted in an analogous way to RBS, but with the important difference that the elemental spectra are separated, and not superimposed on a background as in RBS. Some of the measurements made with a HIERDA system on the ANTARES Tandem Accelerator at ANSTO are described. 1 refs., 4 figs.

  8. A device for the color measurement and detection of spots on the skin.

    Science.gov (United States)

    Pladellorens, Josep; Pintó, Agustí; Segura, Jordi; Cadevall, Cristina; Antó, Joan; Pujol, Jaume; Vilaseca, Meritxell; Coll, Joaquín

    2008-02-01

    In this work, we present a new and fast easy-to-use device that allows the measurement of color and the detection of spots on the human skin. The developed device is highly practical for relatively untrained operators and uses inexpensive consumer equipment, such as a CCD color camera, a light source composed of LEDs and a laptop. The knowledge of the color of the skin and the detection of spots can be useful in several areas such as in dermatology applications, the cosmetics industry, the biometrics field, health care, etc. In order to perform these measurements the system takes a picture of the skin. After that, the operator selects the region of the skin to be analyzed on the displayed image and the system provides the CIELAB color coordinates, the chroma and the ITA parameter (Individual Tipology Angle), allowing the comparison with other reference images by means of CIELAB color differences. The system also detects spots, such as freckles, age spots, sunspots, pimples, black heads, etc., in a determined region, allowing the objective measurement of their size and area. The colorimetric information provided by a conventional spectrophotometer for the tested samples and the computed values obtained with the new developed system are quite similar, meaning that the developed system can be used to perform color measurements with relatively high accuracy. On the other hand, the feasibility of the system in order to detect and measure spots on the human skin has also been checked over a great amount of images, obtaining results with high precision. In this work, we present a new system that may be very useful in order to measure the color and to detect spots of the skin. Its portability and easy applicability will be very useful in dermatologic and cosmetic studies.

  9. Detecting Periprocedural Myocardial Infarction in Contemporary Percutaneous Coronary Intervention Trials

    NARCIS (Netherlands)

    Spitzer, Ernest; de Vries, Ton; Cavalcante, Rafael; Tuinman, Marieke; Rademaker-Havinga, Tessa; Alkema, Maaike; Morel, Marie-Angele; Soliman, Osama I.; Onuma, Yoshinobu; van Es, Gerrit-Anne; Tijssen, Jan G. P.; McFadden, Eugene; Serruys, Patrick W.

    2017-01-01

    This study sought to investigate the differences in detecting (e.g., triggering) periprocedural myocardial infarction (PMI) among 3 current definitions. PMI is a frequent component of primary endpoints in coronary device trials. Identification of all potential suspected events is critical for

  10. Sequential blind identification of underdetermined mixtures using a novel deflation scheme.

    Science.gov (United States)

    Zhang, Mingjian; Yu, Simin; Wei, Gang

    2013-09-01

    In this brief, we consider the problem of blind identification in underdetermined instantaneous mixture cases, where there are more sources than sensors. A new blind identification algorithm, which estimates the mixing matrix in a sequential fashion, is proposed. By using the rank-1 detecting device, blind identification is reformulated as a constrained optimization problem. The identification of one column of the mixing matrix hence reduces to an optimization task for which an efficient iterative algorithm is proposed. The identification of the other columns of the mixing matrix is then carried out by a generalized eigenvalue decomposition-based deflation method. The key merit of the proposed deflation method is that it does not suffer from error accumulation. The proposed sequential blind identification algorithm provides more flexibility and better robustness than its simultaneous counterpart. Comparative simulation results demonstrate the superior performance of the proposed algorithm over the simultaneous blind identification algorithm.

  11. A signal-detection analysis of eyewitness identification across the adult lifespan.

    Science.gov (United States)

    Colloff, Melissa F; Wade, Kimberley A; Wixted, John T; Maylor, Elizabeth A

    2017-05-01

    Middle-aged and older adults are frequently victims and witnesses of crime, but knowledge of how identification performance changes over the adult life span is sparse. The authors asked young (18-30 years), middle-aged (31-59 years), and older (60-95 years) adults (N = 2,670) to watch a video of a mock crime and to attempt to identify the culprit from a fair lineup (in which all of the lineup members matched the appearance of the suspect) or an unfair lineup (in which the suspect stood out). They also asked subjects to provide confidence ratings for their identification decisions. To examine identification performance, the authors used a standard response-type analysis, receiver operating characteristic analysis, and signal-detection process modeling. The results revealed that, in fair lineups, aging was associated with a genuine decline in recognition ability-discriminability-and not an increased willingness to choose. Perhaps most strikingly, middle-aged and older adults were generally effective at regulating their confidence judgments to reflect the likely accuracy of their suspect identification decisions. Model-fitting confirmed that the older adults spread their decision criteria such that identifications made with high confidence were likely to be highly accurate, despite the substantial decline in discriminability with age. In unfair lineups, ability to discriminate between innocent and guilty suspects was poor in all age groups. The research enhances theoretical understanding of the ways in which identification behavior changes with age, and has important practical implications for how legal decision-makers should interpret identifications made by middle-aged and older eyewitnesses. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  12. Detection of cadmium sulphide nanoparticles by using screen-printed electrodes and a handheld device

    International Nuclear Information System (INIS)

    Merkoci, Arben; Marcolino-Junior, Luiz Humberto; MarIn, Sergio; Fatibello-Filho, Orlando; Alegret, Salvador

    2007-01-01

    A simple method based on screen-printed electrodes and a handheld potentiostatic device is reported for the detection of water soluble CdS quantum dots modified with glutathione. The detection method is based on the stripping of electrochemically reduced cadmium at pH 7.0 by using square wave voltammetry. Various parameters that affect the sensitivity of the method are optimized. QD suspension volumes of 20 μl and a number of around 2 x 10 11 CdS quantum dots have been able to be detected. The proposed method should be of special interest for bioanalytical assays, where CdS quantum dots can be used as electrochemical tracers

  13. Detection panel for identification of twelve hemorrhagic viruses using real-time RT-PCR.

    Science.gov (United States)

    Fajfr, M; Neubauerová, V; Pajer, P; Kubíčková, P; Růžek, D

    2014-09-01

    Viral hemorrhagic fevers are caused by viruses from four viral families and develop diseases with high fatality rates. However, no commercial diagnostic assay for these pathogens is available. We developed real-time RT-PCR assays for viruses Ebola, Marburg, Lassa, Guanarito, Machupo, Junin, Sabiá, Seoul, Puumala, Hantaan, Crimean-Congo hemorrhagic fever virus and Rift Valley fever virus. The assays were optimized for identical reaction conditions and can be performed using several types of real-time PCR instruments, both capillary and plate, including a portable Ruggedized Advanced Pathogen Identification Device (R.A.P.I.D.) (Idaho Technology, Inc.). In combination with primers and probes from previously published studies, we present a simple system for rapid identification of hemorrhagic filoviruses, arenaviruses and bunyaviruses with sufficient sensitivity for first contact laboratory and diagnosis under field conditions.

  14. Electrical Impedance Spectroscopy for Detection of Cells in Suspensions Using Microfluidic Device with Integrated Microneedles

    Directory of Open Access Journals (Sweden)

    Muhammad Asraf Mansor

    2017-02-01

    Full Text Available In this study, we introduce novel method of flow cytometry for cell detection based on impedance measurements. The state of the art method for impedance flow cytometry detection utilizes an embedded electrode in the microfluidic to perform measurement of electrical impedance of the presence of cells at the sensing area. Nonetheless, this method requires an expensive and complicated electrode fabrication process. Furthermore, reuse of the fabricated electrode also requires an intensive and tedious cleaning process. Due to that, we present a microfluidic device with integrated microneedles. The two microneedles are placed at the half height of the microchannel for cell detection and electrical measurement. A commercially-available Tungsten needle was utilized for the microneedles. The microneedles are easily removed from the disposable PDMS (Polydimethylsiloxane microchannel and can be reused with a simple cleaning process, such as washing by ultrasonic cleaning. Although this device was low cost, it preserves the core functionality of the sensor, which is capable of detecting passing cells at the sensing area. Therefore, this device is suitable for low-cost medical and food safety screening and testing process in developing countries.

  15. A compact and portable optofluidic device for detection of liquid properties and label-free sensing

    Science.gov (United States)

    Lahoz, F.; Martín, I. R.; Walo, D.; Gil-Rostra, J.; Yubero, F.; Gonzalez-Elipe, A. R.

    2017-06-01

    Optofluidic lasers have been widely investigated over the last few years mainly because they can be easily integrated in sensor devices. However, high power pulse lasers are required as excitation sources, which, in practice, limit the portability of the system. Trying to overcome some of these limitations, in this paper we propose the combined use of a small CW laser with a Fabry-Perot optofluidic planar microcavity showing high sensitivity and versatility for detection of liquid properties and label-free sensing. Firstly, a fluorescein solution in ethanol is used to demonstrate the high performances of the FP microcavity as a temperature sensor both in the laser (high pump power above laser threshold) and in the fluorescence (low pump power) regimes. A shift in the wavelength of the resonant cavity modes is used to detect changes in the temperature and our results show that high sensitivities could be already obtained using cheap and portable CW diode lasers. In the second part of the paper, the demonstration of this portable device for label-free sensing is illustrated under low CW pumping. The wavelength positions of the optofluidic resonant modes are used to detect glucose concentrations in water solutions using a protein labelled with a fluorescent dye as the active medium.

  16. RFID and Memory Devices Fabricated Integrally on Substrates

    Science.gov (United States)

    Schramm, Harry F.

    2004-01-01

    Electronic identification devices containing radio-frequency identification (RFID) circuits and antennas would be fabricated integrally with the objects to be identified, according to a proposal. That is to say, the objects to be identified would serve as substrates for the deposition and patterning of the materials of the devices used to identify them, and each identification device would be bonded to the identified object at the molecular level. Vacuum arc vapor deposition (VAVD) is the NASA derived process for depositing layers of material on the substrate. This proposal stands in contrast to the current practice of fabricating RFID and/or memory devices as wafer-based, self-contained integrated-circuit chips that are subsequently embedded in or attached to plastic cards to make smart account-information cards and identification badges. If one relies on such a chip to store data on the history of an object to be tracked and the chip falls off or out of the object, then one loses both the historical data and the means to track the object and verify its identity electronically. Also, in contrast is the manufacturing philosophy in use today to make many memory devices. Today s methods involve many subtractive processes such as etching. This proposal only uses additive methods, building RFID and memory devices from the substrate up in thin layers. VAVD is capable of spraying silicon, copper, and other materials commonly used in electronic devices. The VAVD process sprays most metals and some ceramics. The material being sprayed has a very strong bond with the substrate, whether that substrate is metal, ceramic, or even wood, rock, glass, PVC, or paper. An object to be tagged with an identification device according to the proposal must be compatible with a vacuum deposition process. Temperature is seldom an issue as the substrate rarely reaches 150 F (66 C) during the deposition process. A portion of the surface of the object would be designated as a substrate for

  17. A Microfluidic Love-Wave Biosensing Device for PSA Detection Based on an Aptamer Beacon Probe.

    Science.gov (United States)

    Zhang, Feng; Li, Shuangming; Cao, Kang; Wang, Pengjuan; Su, Yan; Zhu, Xinhua; Wan, Ying

    2015-06-11

    A label-free and selective aptamer beacon-based Love-wave biosensing device was developed for prostate specific antigen (PSA) detection. The device consists of the following parts: LiTaO3 substrate with SiO2 film as wave guide layer, two set of inter-digital transducers (IDT), gold film for immobilization of the biorecongniton layer and a polydimethylsiloxane (PDMS) microfluidic channels. DNA aptamer, or "artificial antibody", was used as the specific biorecognition probe for PSA capture. Some nucleotides were added to the 3'-end of the aptamer to form a duplex with the 3'-end, turning the aptamer into an aptamer-beacon. Taking advantage of the selective target-induced assembly changes arising from the "aptamer beacon", highly selective and specific detection of PSA was achieved. Furthermore, PDMS microfluidic channels were designed and fabricated to realize automated quantitative sample injection. After optimization of the experimental conditions, the established device showed good performance for PSA detection between 10 ng/mL to 1 μg/mL, with a detection limit of 10 ng/mL. The proposed sensor might be a promising alternative for point of care diagnostics.

  18. Lab-on-paper micro- and nano-analytical devices: Fabrication, modification, detection and emerging applications

    International Nuclear Information System (INIS)

    Xu, Yuanhong; Liu, Mengli; Kong, Na; Liu, Jingquan

    2016-01-01

    Paper-based chips (PB-chips; also referred to as lab-on-paper chips) are using patterned paper as a substrate in a lab-on-a-chip platform. They represent an outstanding technique for fabrication of analytical devices for multiplex analyte assays. Typical features include low-cost, portability, disposability and small sample consumption. This review (with 211 refs.) gives a comprehensive and critical insight into current trends in terms of materials and techniques for use in fabrication, modification and detection. Following an introduction into the principles of PB-chips, we discuss features of using paper in lab-on-a-chip devices and the proper choice of paper. We then discuss the versatile methods known for fabrication of PB-chips (ranging from photolithography, plasma treatment, ink jet etching, plotting, to printing including flexographic printing). The modification of PB-chips with micro- and nano-materials possessing superior optical or electronic properties is then reviewed, and the final section covers detection techniques (such as colorimetry, electrochemistry, electrochemiluminescence and chemiluminescence) along with specific (bio)analytical examples. A conclusion and outlook section discusses the challenges and future prospectives in this field. (author)

  19. Lab-on-fiber electrophoretic trace mixture separating and detecting an optofluidic device based on a microstructured optical fiber.

    Science.gov (United States)

    Yang, Xinghua; Guo, Xiaohui; Li, Song; Kong, Depeng; Liu, Zhihai; Yang, Jun; Yuan, Libo

    2016-04-15

    We report an in-fiber integrated electrophoretic trace mixture separating and detecting an optofluidic optical fiber sensor based on a specially designed optical fiber. In this design, rapid in situ separation and simultaneous detection of mixed analytes can be realized under electro-osmotic flow in the microstructured optical fiber. To visually display the in-fiber separating and detecting process, two common fluorescent indicators are adopted as the optofluidic analytes in the optical fiber. Results show that a trace amount of the mixture (0.15 μL) can be completely separated within 3.5 min under a high voltage of 5 kV. Simultaneously, the distributed information of the separated analytes in the optical fiber can be clearly obtained by scanning along the optical fiber using a 355 nm laser. The emission from the analytes can be efficiently coupled into the inner core and guides to the remote end of the optical fiber. In addition, the thin cladding around the inner core in the optical fiber can prevent the fluorescent cross talk between the analytes in this design. Compared to previous optical fiber optofluidic devices, this device first realizes simultaneously separating treatment and the detection of the mixed samples in an optical fiber. Significantly, such an in-fiber integrated separating and detecting optofluidic device can find wide applications in various analysis fields involves mixed samples, such as biology, chemistry, and environment.

  20. Chemical Detection Based on Adsorption-Induced and Photo-Induced Stresses in MEMS Devices

    Energy Technology Data Exchange (ETDEWEB)

    Datskos, P.G.

    1999-04-05

    Recently there has been an increasing demand to perform real-time in-situ chemical detection of hazardous materials, contraband chemicals, and explosive chemicals. Currently, real-time chemical detection requires rather large analytical instrumentation that are expensive and complicated to use. The advent of inexpensive mass produced MEMS (micro-electromechanical systems) devices opened-up new possibilities for chemical detection. For example, microcantilevers were found to respond to chemical stimuli by undergoing changes in their bending and resonance frequency even when a small number of molecules adsorb on their surface. In our present studies, we extended this concept by studying changes in both the adsorption-induced stress and photo-induced stress as target chemicals adsorb on the surface of microcantilevers. For example, microcantilevers that have adsorbed molecules will undergo photo-induced bending that depends on the number of absorbed molecules on the surface. However, microcantilevers that have undergone photo-induced bending will adsorb molecules on their surfaces in a distinctly different way. Depending on the photon wavelength and microcantilever material, the microcantilever can be made to bend by expanding or contracting the irradiated surface. This is important in cases where the photo-induced stresses can be used to counter any adsorption-induced stresses and increase the dynamic range. Coating the surface of the microstructure with a different material can provide chemical specificity for the target chemicals. However, by selecting appropriate photon wavelengths we can change the chemical selectivity due to the introduction of new surface states in the MEMS device. We will present and discuss our results on the use of adsorption-induced and photo-induced bending of microcantilevers for chemical detection.

  1. Development of corrosion condition sensing and monitoring system using radio-frequency identification devices (RFID) : progress report 2

    Energy Technology Data Exchange (ETDEWEB)

    Gu, G.P.; Li, J.; Liu, P.; Bibby, D.; Zheng, W.; Lo, J. [Natural Resources Canada, Ottawa, ON (Canada). CANMET Materials Technology Laboratory

    2008-12-15

    The development of a corrosion severity monitoring system that used radio-frequency identification device (RIFD) technology was discussed. A corrosion monitoring sensor was integrated with a tag modified to partially block the radio frequency signal. The metallic coating caused a frequency shift of the device's reader antenna in order to allow for the accurate characterization of metal coatings. Communications between the tag and the reader were re-established as the corrosion process gradually deteriorated the coating. The method was tested experimentally with 3 RFID systems using both active and passive tags were assembled. A passive tag was covered in aluminum foil. Results of the experiment showed that the metallic coating interfered with RFID signals. A cold-spray technology was used to coat tags with metal alloys. The surface morphology of the coatings was tested to determine optimum coating parameters. Further studies are being conducted to develop software for the technology. 4 refs., 11 figs.

  2. Leak detection device for nuclear reactor pressure vessel

    International Nuclear Information System (INIS)

    Ikeda, Jun.

    1988-01-01

    Purpose: To test the leakage of a nuclear reactor pressure vessel during stopping for a short period of time with no change to the pressure vessel itself. Constitution: The device of the present invention comprises two O-rings disposed on the flange surface that connects a pressure vessel main body and an upper cover, a leak-off pipeway derived from the gap of the O-rings at the flange surface to the outside of the pressure vessel, a pressure detection means connected to the end of the pipeway, a humidity detection means disposed to the lead-off pipeway, a humidity detection means disposed to the lead-off pipeway, and gas supply means and gas suction means disposed each by way of a check valve to a side pipe branched from the pipeway. After stopping the operation of the nuclear reactor and pressurizing the pressure vessel by filling water, gases supplied to the gap between the O-rings at the flange surface by opening the check valve. In a case where water in the pressure vessel should leak to the flange surface, when gas suction is applied by properly opening the check valve, increase in the humidity due to the steams of leaked water diffused into the gas is detected to recognize the occurrence of leakage. (Kamimura, M.)

  3. Study of hydrogenated amorphous silicon devices under intense electric field: application to nuclear detection

    International Nuclear Information System (INIS)

    Ilie, A.

    1996-01-01

    The goal of this work was the study, development and optimization of hydrogenated amorphous silicon (a-Si:H) devices for use in detection of ionizing radiation in applications connected to the nuclear industry. Thick p-i-n devices, capable of withstanding large electric fields (up to 10 6 V/cm) with small currents (nA/cm 2 ), were proposed and developed. In order to decrease fabrication time, films were made using the 'He diluted' PECVD process and compared to standard a-Si:H films. Aspects connected to specific detector applications as well as to the fundamental physics of a-Si:H were considered: the internal electric field technique, in which the depletion charge was measured as a function of the applied bias voltage; study of the leakage current of p-i-n devices permitted us to demonstrate different regimes: depletion, field-enhanced thermal generation and electronic injection across the p layer. The effect of the electric field on the thermal generation of the carriers was studied considering the Poole-Frenkel and tunneling mechanisms. A model was developed taking under consideration the statistics of the correlated states and electron-phonon coupling. The results suggest that mechanisms not included in the 'standard model' of a Si:h need to be considered, such as defect relaxation, a filed-dependent mobility edge etc...; a new metastable phenomenon, called 'forming', induced by prolonged exposure to a strong electric field, was observed and studied. It is characterized by marked decrease of the leakage current and the detector noise, and increase in the breakdown voltage, as well as an improvement of carrier collection efficiency. This forming process appears to be principally due to an activation of the dopants in the p layer; finally, the capacity of thick p-i-n a Si:H devices to detect ionizing radiation has been evaluated. We show that it is possible, with 20-50 micron thick p-i-n devices, to detect the full spectrum of alpha and beta particles. With an

  4. 21 CFR 882.5050 - Biofeedback device.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Biofeedback device. 882.5050 Section 882.5050 Food... DEVICES NEUROLOGICAL DEVICES Neurological Therapeutic Devices § 882.5050 Biofeedback device. (a) Identification. A biofeedback device is an instrument that provides a visual or auditory signal corresponding to...

  5. Multi-gene detection and identification of mosquito-borne RNA viruses using an oligonucleotide microarray.

    Directory of Open Access Journals (Sweden)

    Nathan D Grubaugh

    Full Text Available BACKGROUND: Arthropod-borne viruses are important emerging pathogens world-wide. Viruses transmitted by mosquitoes, such as dengue, yellow fever, and Japanese encephalitis viruses, infect hundreds of millions of people and animals each year. Global surveillance of these viruses in mosquito vectors using molecular based assays is critical for prevention and control of the associated diseases. Here, we report an oligonucleotide DNA microarray design, termed ArboChip5.1, for multi-gene detection and identification of mosquito-borne RNA viruses from the genera Flavivirus (family Flaviviridae, Alphavirus (Togaviridae, Orthobunyavirus (Bunyaviridae, and Phlebovirus (Bunyaviridae. METHODOLOGY/PRINCIPAL FINDINGS: The assay utilizes targeted PCR amplification of three genes from each virus genus for electrochemical detection on a portable, field-tested microarray platform. Fifty-two viruses propagated in cell-culture were used to evaluate the specificity of the PCR primer sets and the ArboChip5.1 microarray capture probes. The microarray detected all of the tested viruses and differentiated between many closely related viruses such as members of the dengue, Japanese encephalitis, and Semliki Forest virus clades. Laboratory infected mosquitoes were used to simulate field samples and to determine the limits of detection. Additionally, we identified dengue virus type 3, Japanese encephalitis virus, Tembusu virus, Culex flavivirus, and a Quang Binh-like virus from mosquitoes collected in Thailand in 2011 and 2012. CONCLUSIONS/SIGNIFICANCE: We demonstrated that the described assay can be utilized in a comprehensive field surveillance program by the broad-range amplification and specific identification of arboviruses from infected mosquitoes. Furthermore, the microarray platform can be deployed in the field and viral RNA extraction to data analysis can occur in as little as 12 h. The information derived from the ArboChip5.1 microarray can help to establish

  6. Devices, systems, and methods for detecting nucleic acids using sedimentation

    Energy Technology Data Exchange (ETDEWEB)

    Koh, Chung-Yan; Schaff, Ulrich Y.; Sommer, Gregory J.

    2017-10-24

    Embodiments of the present invention are directed toward devices, systems, and method for conducting nucleic acid purification and quantification using sedimentation. In one example, a method includes generating complexes which bind to a plurality of beads in a fluid sample, individual ones of the complexes comprising a nucleic acid molecule such as DNA or RNA and a labeling agent. The plurality of beads including the complexes may be transported through a density media, wherein the density media has a density lower than a density of the beads and higher than a density of the fluid sample, and wherein the transporting occurs, at least in part, by sedimentation. Signal may be detected from the labeling agents of the complexes.

  7. Multi-Device to Multi-Device (MD2MD Content-Centric Networking Based on Multi-RAT Device

    Directory of Open Access Journals (Sweden)

    Cheolhoon Kim

    2017-11-01

    Full Text Available This paper proposes a method whereby a device can transmit and receive information using a beacon, and also describes application scenarios for the proposed method. In a multi-device to multi-device (MD2MD content-centric networking (CCN environment, the main issue involves searching for and connecting to nearby devices. However, if a device can’t find another device that satisfies its requirements, the connection is delayed due to the repetition of processes. It is possible to rapidly connect to a device without repetition through the selection of the optimal device using the proposed method. Consequently, the proposed method and scenarios are advantageous in that they enable efficient content identification and delivery in a content-centric Internet of Things (IoT environment, in which multiple mobile devices coexist.

  8. Comparison of real-time classification systems for arrhythmia detection on Android-based mobile devices.

    Science.gov (United States)

    Leutheuser, Heike; Gradl, Stefan; Kugler, Patrick; Anneken, Lars; Arnold, Martin; Achenbach, Stephan; Eskofier, Bjoern M

    2014-01-01

    The electrocardiogram (ECG) is a key diagnostic tool in heart disease and may serve to detect ischemia, arrhythmias, and other conditions. Automatic, low cost monitoring of the ECG signal could be used to provide instantaneous analysis in case of symptoms and may trigger the presentation to the emergency department. Currently, since mobile devices (smartphones, tablets) are an integral part of daily life, they could form an ideal basis for automatic and low cost monitoring solution of the ECG signal. In this work, we aim for a realtime classification system for arrhythmia detection that is able to run on Android-based mobile devices. Our analysis is based on 70% of the MIT-BIH Arrhythmia and on 70% of the MIT-BIH Supraventricular Arrhythmia databases. The remaining 30% are reserved for the final evaluation. We detected the R-peaks with a QRS detection algorithm and based on the detected R-peaks, we calculated 16 features (statistical, heartbeat, and template-based). With these features and four different feature subsets we trained 8 classifiers using the Embedded Classification Software Toolbox (ECST) and compared the computational costs for each classification decision and the memory demand for each classifier. We conclude that the C4.5 classifier is best for our two-class classification problem (distinction of normal and abnormal heartbeats) with an accuracy of 91.6%. This classifier still needs a detailed feature selection evaluation. Our next steps are implementing the C4.5 classifier for Android-based mobile devices and evaluating the final system using the remaining 30% of the two used databases.

  9. Microfluidics & nanotechnology: Towards fully integrated analytical devices for the detection of cancer biomarkers

    KAUST Repository

    Perozziello, Gerardo; Candeloro, Patrizio; Gentile, Francesco T.; Nicastri, Annalisa; Perri, Angela Mena; Coluccio, Maria Laura; Adamo, A.; Pardeo, Francesca; Catalano, Rossella; Parrotta, Elvira; Espinosa, Horacio Dante; Cuda, Giovanni; Di Fabrizio, Enzo M.

    2014-01-01

    In this paper, we describe an innovative modular microfluidic platform allowing filtering, concentration and analysis of peptides from a complex mixture. The platform is composed of a microfluidic filtering device and a superhydrophobic surface integrating surface enhanced Raman scattering (SERS) sensors. The microfluidic device was used to filter specific peptides (MW 1553.73 D) derived from the BRCA1 protein, a tumor-suppressor molecule which plays a pivotal role in the development of breast cancers, from albumin (66.5 KD), the most represented protein in human plasma. The filtering process consisted of driving the complex mixture through a porous membrane having a cut-off of 12-14 kD by hydrodynamic flow. The filtered samples coming out of the microfluidic device were subsequently deposited on a superhydrophobic surface formed by micro pillars on top of which nanograins were fabricated. The nanograins coupled to a Raman spectroscopy instrument acted as a SERS sensor and allowed analysis of the filtered sample on top of the surface once it evaporated. By using the presented platform, we demonstrate being able to sort small peptides from bigger proteins and to detect them by using a label-free technique at a resolution down to 0.1 ng μL-1. The combination of microfluidics and nanotechnology to develop the presented microfluidic platform may give rise to a new generation of biosensors capable of detecting low concentration samples from complex mixtures without the need for any sample pretreatment or labelling. The developed devices could have future applications in the field of early diagnosis of severe illnesses, e.g. early cancer detection. This journal is

  10. Study of various n-type organic semiconductors on ultraviolet detective and electroluminescent properties of optoelectronic integrated device

    Science.gov (United States)

    Deng, Chaoxu; Shao, Bingyao; Zhao, Dan; Zhou, Dianli; Yu, Junsheng

    2017-11-01

    Organic optoelectronic integrated device (OID) with both ultraviolet (UV) detective and electroluminescent (EL) properties was fabricated by using a thermally activated delayed fluorescence (TADF) semiconductor of (4s, 6s)-2,4,5,6-tetra(9H-carbazol-9-yl)isophthalonitrile (4CzIPN) as an emitter. The effect of five kinds of n-type organic semiconductors (OSCs) on the enhancement of UV detective and EL properties of OID was systematically studied. The result shows that two orders of magnitude in UV detectivity from 109 to 1011 Jones and 3.3 folds of luminance from 2499 to 8233 cd m-2 could be achieved. The result shows that not only the difference of lowest unoccupied molecular orbital (LUMO) between active layer and OSC but also the variety of electron mobility have a significant effect on the UV detective and EL performance through adjusting electron injection/transport. Additionally, the optimized OSC thickness is beneficial to confine the leaking of holes from the active layer to cathode, leading to the decrease of dark current for high detective performance. This work provides a useful method on broadening OSC material selection and device architecture construction for the realization of high performance OID.

  11. Image change detection systems, methods, and articles of manufacture

    Science.gov (United States)

    Jones, James L.; Lassahn, Gordon D.; Lancaster, Gregory D.

    2010-01-05

    Aspects of the invention relate to image change detection systems, methods, and articles of manufacture. According to one aspect, a method of identifying differences between a plurality of images is described. The method includes loading a source image and a target image into memory of a computer, constructing source and target edge images from the source and target images to enable processing of multiband images, displaying the source and target images on a display device of the computer, aligning the source and target edge images, switching displaying of the source image and the target image on the display device, to enable identification of differences between the source image and the target image.

  12. Detection, Identification, Location, and Remote Sensing using SAW RFID Sensor Tags

    Science.gov (United States)

    Barton, Richard J.

    2009-01-01

    In this presentation, we will consider the problem of simultaneous detection, identification, location estimation, and remote sensing for multiple objects. In particular, we will describe the design and testing of a wireless system capable of simultaneously detecting the presence of multiple objects, identifying each object, and acquiring both a low-resolution estimate of location and a high-resolution estimate of temperature for each object based on wireless interrogation of passive surface acoustic wave (SAW) radiofrequency identification (RFID) sensor tags affixed to each object. The system is being studied for application on the lunar surface as well as for terrestrial remote sensing applications such as pre-launch monitoring and testing of spacecraft on the launch pad and monitoring of test facilities. The system utilizes a digitally beam-formed planar receiving antenna array to extend range and provide direction-of-arrival information coupled with an approximate maximum-likelihood signal processing algorithm to provide near-optimal estimation of both range and temperature. The system is capable of forming a large number of beams within the field of view and resolving the information from several tags within each beam. The combination of both spatial and waveform discrimination provides the capability to track and monitor telemetry from a large number of objects appearing simultaneously within the field of view of the receiving array. In the presentation, we will summarize the system design and illustrate several aspects of the operational characteristics and signal structure. We will examine the theoretical performance characteristics of the system and compare the theoretical results with results obtained from experiments in both controlled laboratory environments and in the field.

  13. Detection of fecal contamination on beef meat surfaces using handheld fluorescence imaging device (HFID)

    Science.gov (United States)

    Oh, Mirae; Lee, Hoonsoo; Cho, Hyunjeong; Moon, Sang-Ho; Kim, Eun-Kyung; Kim, Moon S.

    2016-05-01

    Current meat inspection in slaughter plants, for food safety and quality attributes including potential fecal contamination, is conducted through by visual examination human inspectors. A handheld fluorescence-based imaging device (HFID) was developed to be an assistive tool for human inspectors by highlighting contaminated food and food contact surfaces on a display monitor. It can be used under ambient lighting conditions in food processing plants. Critical components of the imaging device includes four 405-nm 10-W LEDs for fluorescence excitation, a charge-coupled device (CCD) camera, optical filter (670 nm used for this study), and Wi-Fi transmitter for broadcasting real-time video/images to monitoring devices such as smartphone and tablet. This study aimed to investigate the effectiveness of HFID in enhancing visual detection of fecal contamination on red meat, fat, and bone surfaces of beef under varying ambient luminous intensities (0, 10, 30, 50 and 70 foot-candles). Overall, diluted feces on fat, red meat and bone areas of beef surfaces were detectable in the 670-nm single-band fluorescence images when using the HFID under 0 to 50 foot-candle ambient lighting.

  14. Environmental DNA (eDNA From the Wake of the Whales: Droplet Digital PCR for Detection and Species Identification

    Directory of Open Access Journals (Sweden)

    C. Scott Baker

    2018-04-01

    Full Text Available Genetic sampling for identification of species, subspecies or stock of whales, dolphins and porpoises at sea remains challenging. Most samples have been collected with some form of a biopsy dart requiring a close approach of a vessel while the individual is at the surface. Here we have adopted droplet digital (ddPCR technology for detection and species identification of cetaceans using environmental (eDNA collected from seawater. We conducted a series of eDNA sampling experiments during 25 encounters with killer whales, Orcinus orca, in Puget Sound (the Salish Sea. The regular habits of killer whales in these inshore waters allowed us to locate pods and collect seawater, at an initial distance of 200 m and at 15-min intervals, for up to 2 h after the passage of the whales. To optimize detection, we designed a set of oligonucleotide primers and probes to target short fragments of the mitochondrial (mtDNA control region, with a focus on identification of known killer whale ecotypes. We confirmed the potential to detect eDNA in the wake of the whales for up to 2 h, despite movement of the water mass by several kilometers due to tidal currents. Re-amplification and sequencing of the eDNA barcode confirmed that the ddPCR detection included the “southern resident community” of killer whales, consistent with the calls from hydrophone recordings and visual observations.

  15. From Data Acquisition to Data Fusion: A Comprehensive Review and a Roadmap for the Identification of Activities of Daily Living Using Mobile Devices

    Directory of Open Access Journals (Sweden)

    Ivan Miguel Pires

    2016-02-01

    Full Text Available This paper focuses on the research on the state of the art for sensor fusion techniques, applied to the sensors embedded in mobile devices, as a means to help identify the mobile device user’s daily activities. Sensor data fusion techniques are used to consolidate the data collected from several sensors, increasing the reliability of the algorithms for the identification of the different activities. However, mobile devices have several constraints, e.g., low memory, low battery life and low processing power, and some data fusion techniques are not suited to this scenario. The main purpose of this paper is to present an overview of the state of the art to identify examples of sensor data fusion techniques that can be applied to the sensors available in mobile devices aiming to identify activities of daily living (ADLs.

  16. From Data Acquisition to Data Fusion: A Comprehensive Review and a Roadmap for the Identification of Activities of Daily Living Using Mobile Devices

    Science.gov (United States)

    Pires, Ivan Miguel; Garcia, Nuno M.; Pombo, Nuno; Flórez-Revuelta, Francisco

    2016-01-01

    This paper focuses on the research on the state of the art for sensor fusion techniques, applied to the sensors embedded in mobile devices, as a means to help identify the mobile device user’s daily activities. Sensor data fusion techniques are used to consolidate the data collected from several sensors, increasing the reliability of the algorithms for the identification of the different activities. However, mobile devices have several constraints, e.g., low memory, low battery life and low processing power, and some data fusion techniques are not suited to this scenario. The main purpose of this paper is to present an overview of the state of the art to identify examples of sensor data fusion techniques that can be applied to the sensors available in mobile devices aiming to identify activities of daily living (ADLs). PMID:26848664

  17. Phenomenon detection device

    International Nuclear Information System (INIS)

    Suzuki, Yasuo.

    1994-01-01

    Detection signals for a specific phenomenon outputted from any of detectors are distributed by way of half mirrors and inputted to a logic discrimination circuit by way of a photoelectric convertor. The photoelectric convertor detects the quantity of light corresponding to the optical signals from more than two detectors which detected the phenomenon, and outputs detection signals to the logic discrimination circuit. If the phenomenon is detected, since both inputs turn ON in the logic discrimination circuit in accordance with the predetermined logical sum, the occurrence of a specific phenomenon is detected. Thus, an optical system substantially comprises half mirrors, reflection mirrors and photoelectric convertor in combination provides a logic circuit. Since the circuit which transmits signals of the detectors is constituted with an optical system using the half mirrors, the number of parts constituting the logic circuit can greatly be saved. In addition, since the optical system comprises mirrors or half mirrors which have been used so far, they can be used, once assembled, quasipermanently, and the reliability can be enhanced greatly. (N.H.)

  18. Cost and detection rate of glaucoma screening with imaging devices in a primary care center

    Directory of Open Access Journals (Sweden)

    Anton A

    2017-02-01

    Full Text Available Alfonso Anton,1–4 Monica Fallon,3,5 Francesc Cots,2 María A Sebastian,6 Antonio Morilla-Grasa,4 Sergi Mojal,3 Xavier Castells2 1Medicine School, Universidad Internacional de Cataluña, 2Servei d’Estudies, Parc de Salut Mar, 3Instituto Hospital del Mar de Investigaciones Médicas (IMIM, 4Glaucoma Department, Instituto Catalán de Retina (ICR, 5Universidad Autónoma de Barcelona, 6Centro de Atención Primaria Larrard, Barcelona, Spain Purpose: To analyze the cost and detection rate of a screening program for detecting glaucoma with imaging devices. Materials and methods: In this cross-sectional study, a glaucoma screening program was applied in a population-based sample randomly selected from a population of 23,527. Screening targeted the population at risk of glaucoma. Examinations included optic disk tomography (Heidelberg retina tomograph [HRT], nerve fiber analysis, and tonometry. Subjects who met at least 2 of 3 endpoints (HRT outside normal limits, nerve fiber index ≥30, or tonometry ≥21 mmHg were referred for glaucoma consultation. The currently established (“conventional” detection method was evaluated by recording data from primary care and ophthalmic consultations in the same population. The direct costs of screening and conventional detection were calculated by adding the unit costs generated during the diagnostic process. The detection rate of new glaucoma cases was assessed. Results: The screening program evaluated 414 subjects; 32 cases were referred for glaucoma consultation, 7 had glaucoma, and 10 had probable glaucoma. The current detection method assessed 677 glaucoma suspects in the population, of whom 29 were diagnosed with glaucoma or probable glaucoma. Glaucoma screening and the conventional detection method had detection rates of 4.1% and 3.1%, respectively, and the cost per case detected was 1,410 and 1,435€, respectively. The cost of screening 1 million inhabitants would be 5.1 million euros and would allow

  19. Tube leak detection device and acoustic sensor support device for moisture separating heater

    International Nuclear Information System (INIS)

    Miyabe, Keisuke; Kobayashi, Takefumi.

    1995-01-01

    The device of the present invention comprises an acoustic sensor which detects leak sounds when leak occurs in a heating tube of a moisture separating heater incorporated into a plant, a threshold value memory and switching mechanism containing each of threshold values on every power of a plant, and a leak judging mechanism for judging presence or absence of leaks by comparing a selected threshold value and signals given from the acoustic sensor. Background noises changing currently during operation of a steam turbine plant are compared with a threshold value greater than the background noises in the leak judging mechanism, and they are judged as 'no leak' so as not to recognize them as 'presence of tube leak'. Output values from the acoustic sensor are obtained on every frequency component, and standard frequency spectra are selected by turbine load corresponding signals using a standard spectra memory and switching mechanism. They are sent to a leak judging mechanism to analyze the acoustic signals using a frequency analyzer and compare them with the frequency spectral thereby judging leaks. (N.H.)

  20. Inaccuracy of transthoracic echocardiography for the identification of right-sided vegetation in patients with no history of intravenous drug abuse or cardiac device insertion.

    Science.gov (United States)

    Xie, Jiang; Liu, Shuang; Yang, Jinghua; Xu, Jie; Zhu, Guangfa

    2014-06-01

    The use of transthoracic echocardiography (TTE) to identify right-sided infective endocarditis (RSIE) vegetation is controversial. Data are scarce for patients with no history of intravenous drug abuse (IVDA) or cardiac device insertion. This study analysed the consistency of presurgical echocardiographic results with surgical findings for vegetation identification, and the factors that influence accuracy of echocardiography. This retrospective trial divided infective endocarditis (IE) patients into three subgroups according to the results of their presurgical TTE: left-sided native IE (LSNIE), left-sided prosthetic valve IE (LSPIE) and RSIE. The accuracy of TTE was tested by comparing vegetation (number and location), detected presurgery by TTE, with actual findings during surgery. In total, 416 patients were analysed, 322 with LSNIE, 31 with LSPIE and 63 with RSIE. Consistency between TTE findings and surgical results was lower in the RSIE group compared with the LSPIE and LSNIE groups. Consistency was lowered by the presence of vegetation in multiple locations and atypical distribution--both of which were increased in the RSIE group. The chance of vegetation in both sides of the heart rose with increased numbers of vegetation locations in RSIE patients. A high proportion of RSIE patients had congenital heart defects, mostly ventricular septal defects. TTE may be unsuitable for RSIE patients with no history of IVDA or cardiac device insertion, because multifocal and atypically distributed vegetation may influence detection accuracy. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  1. Suppression background device in neutron detection by a scintillation detector

    International Nuclear Information System (INIS)

    Degtyarev, A.P.; Kozyr', Yu.E.; Prokopets, G.A.

    1980-01-01

    A pulse shape discriminator for suppression of cosmic and gamma background as well as for suppression of intrinsic noises of a photomultiplier is described. Identification of signals of background and neutrons is performed by means of comparison of relative intensity of fast and slow components of scintillator luminescence. Basic discriminator flowsheet which contains integrating and differential RC circuits and time-to-amplitude converter is given. The discriminator provides minimum energy of detected neutrons equal to 500 keV when using a FEhU-36 neutron detector with a stilbene crystal [ru

  2. Forming and detection of digital watermarks in the System for Automatic Identification of VHF Transmissions

    Directory of Open Access Journals (Sweden)

    О. В. Шишкін

    2013-07-01

    Full Text Available Forming and detection algorithms for digital watermarks are designed for automatic identification of VHF radiotelephone transmissions in the maritime and aeronautical mobile services. An audible insensitivity and interference resistance of embedded digital data are provided by means of OFDM technology jointly with normalized distortions distribution and data packet detection by the hash-function. Experiments were carried out on the base of ship’s radio station RT-2048 Sailor and USB ADC-DAC module of type Е14-140M L-CARD in the off-line processing regime in Matlab medium

  3. Combined effects of expectations and visual uncertainty upon detection and identification of a target in the fog.

    Science.gov (United States)

    Quétard, Boris; Quinton, Jean-Charles; Colomb, Michèle; Pezzulo, Giovanni; Barca, Laura; Izaute, Marie; Appadoo, Owen Kevin; Mermillod, Martial

    2015-09-01

    Detecting a pedestrian while driving in the fog is one situation where the prior expectation about the target presence is integrated with the noisy visual input. We focus on how these sources of information influence the oculomotor behavior and are integrated within an underlying decision-making process. The participants had to judge whether high-/low-density fog scenes displayed on a computer screen contained a pedestrian or a deer by executing a mouse movement toward the response button (mouse-tracking). A variable road sign was added on the scene to manipulate expectations about target identity. We then analyzed the timing and amplitude of the deviation of mouse trajectories toward the incorrect response and, using an eye tracker, the detection time (before fixating the target) and the identification time (fixations on the target). Results revealed that expectation of the correct target results in earlier decisions with less deviation toward the alternative response, this effect being partially explained by the facilitation of target identification.

  4. Detecting the Use of Intentionally Transmitting Personal Electronic Devices Onboard Commercial Aircraft

    Science.gov (United States)

    Woods, Randy; Ely, Jay J.; Vahala, Linda

    2003-01-01

    The need to detect unauthorized usage of intentionally transmitting portable electronic devices (PEDs) onboard commercial aircraft is growing, while still allowing passengers to use selected unintentionally transmitting devices, such as laptop computers and CD players during non-critical stages of flight. The following paper presents an installed system for detecting PEDs over multiple frequency bands. Additionally, the advantages of a fixed verses mobile system are discussed. While data is presented to cover the frequency range of 20 MHz to 6.5 GHz, special attention was given to the Cellular/PCS bands as well as Bluetooth and the FRS radio bands. Measurement data from both the semi-anechoic and reverberation chambers are then analyzed and correlated with data collected onboard a commercial aircraft to determine the dominant mode of coupling inside the passenger cabin of the aircraft versus distance from the source. As a final check of system feasibility, several PEDs transmission signatures were recorded and compared with the expected levels.

  5. Fault detection and identification for a class of continuous piecewise affine systems with unknown subsystems and partitions

    NARCIS (Netherlands)

    Le quang, Thuan; Baldi, S.

    2018-01-01

    This paper establishes a novel online fault detection and identification strategy for a class of continuous piecewise affine (PWA) systems, namely, bimodal and trimodal PWA systems. The main contributions with respect to the state-of-the-art are the recursive nature of the proposed scheme and the

  6. Identification of Sarcosine as a Target Molecule for the Canine Olfactory Detection of Prostate Carcinoma.

    Science.gov (United States)

    Pacik, Dalibor; Plevova, Mariana; Urbanova, Lucie; Lackova, Zuzana; Strmiska, Vladislav; Necas, Alois; Heger, Zbynek; Adam, Vojtech

    2018-03-21

    The hypothesis that dogs can detect malignant tumours through the identification of specific molecules is nearly 30 years old. To date, several reports have described the successful detection of distinct types of cancer. However, is still a lack of data regarding the specific molecules that can be recognized by a dog's olfactory apparatus. Hence, we performed a study with artificially prepared, well-characterized urinary specimens that were enriched with sarcosine, a widely reported urinary biomarker for prostate cancer (PCa). For the purposes of the study, a German shepherd dog was utilized for analyses of 60 positive and 120 negative samples. Our study provides the first evidence that a sniffer dog specially trained for the olfactory detection of PCa can recognize sarcosine in artificial urine with a performance [sensitivity of 90%, specificity of 95%, and precision of 90% for the highest amount of sarcosine (10 µmol/L)] that is comparable to the identification of PCa-diagnosed subjects (sensitivity of 93.5% and specificity of 91.6%). This study casts light on the unrevealed phenomenon of PCa olfactory detection and opens the door for further studies with canine olfactory detection and cancer diagnostics.

  7. A Pre-Detection Based Anti-Collision Algorithm with Adjustable Slot Size Scheme for Tag Identification

    Directory of Open Access Journals (Sweden)

    Chiu-Kuo LIANG

    2015-06-01

    Full Text Available One of the research areas in RFID systems is a tag anti-collision protocol; how to reduce identification time with a given number of tags in the field of an RFID reader. There are two types of tag anti-collision protocols for RFID systems: tree based algorithms and slotted aloha based algorithms. Many anti-collision algorithms have been proposed in recent years, especially in tree based protocols. However, there still have challenges on enhancing the system throughput and stability due to the underlying technologies had faced different limitation in system performance when network density is high. Particularly, the tree based protocols had faced the long identification delay. Recently, a Hybrid Hyper Query Tree (H2QT protocol, which is a tree based approach, was proposed and aiming to speedup tag identification in large scale RFID systems. The main idea of H2QT is to track the tag response and try to predict the distribution of tag IDs in order to reduce collisions. In this paper, we propose a pre-detection tree based algorithm, called the Adaptive Pre-Detection Broadcasting Query Tree algorithm (APDBQT, to avoid those unnecessary queries. Our proposed APDBQT protocol can reduce not only the collisions but the idle cycles as well by using pre-detection scheme and adjustable slot size mechanism. The simulation results show that our proposed technique provides superior performance in high density environments. It is shown that the APDBQT is effective in terms of increasing system throughput and minimizing identification delay.

  8. The patient's safety - For a dynamics of improvement. Nr 1. Patient identification

    International Nuclear Information System (INIS)

    2011-03-01

    After a brief recall of some key figures related to radiotherapy in France, a brief analysis of events declared in 2009 (number of sessions, location, treatment technique, error detection process), a brief comment of their consequences, an identification of the event causes (related to work organisation, to patient identification, and to technical tools and devices), this publication indicated good practices for a safer patient identification (use of a photo, implementation of an active questionnaire, double-check procedure, and so on), and evokes innovating techniques: use of bio-metric data, of bar codes, or of an RF-based technology. The bio-metric and questionnaire approaches are briefly commented by members of radiotherapy departments

  9. Paper–based analytical device for detection of extracellular hydrogen peroxide and its application to evaluate drug–induced apoptosis

    International Nuclear Information System (INIS)

    Wang, Qiuhong; Li, Weibo; Qian, Dongping; Li, Yubin; Bao, Ning; Gu, Haiying; Yu, Chunmei

    2016-01-01

    Graphical abstract: A disposable paper-based device based on Au nanoparticles modified indium tin oxide electrode has been designed, which was used to study the extracellular H_2O_2 release from NB4 cells and further applied to evaluate drug-induced apoptosis. - Highlights: • A paper-based analytical device based on Au nanoparticles modified indium tin oxide electrode has been designed. • The proposed device exhibited low detection limit for the electrocatalytical reduction of H_2O_2. • The sensor could be used to detect cellular H_2O_2 released from living cells and further evaluate drug-induced apoptosis. • The approach is low-cost, portable and promising in biological and biomedical applications. - Abstract: Developing cost-effective and simple analysis tools is of vital importance for practical applications in bioanalysis. Here, a disposable paper-based analytical device based on Au nanoparticles modified indium tin oxide electrode has been designed, which was applied for the reliable and non-enzymatic detection of H_2O_2. Due to the excellent electrocatalytic activity of Au nanoparticles, the disposable electrode exhibited favorable performance toward H_2O_2 reduction in the linear concentration range from 0.1 to 15 μM. The detection limit has been estimated to be 0.08 μM, which was lower than certain enzymes and other metal nanomaterials-based sensors. Because of these analytical advantages, the constructed device was used to study the extracellular H_2O_2 release from NB4 cells and further applied to evaluate sodium selenite induced apoptosis. The results obtained by electrochemical method are correlated well with the results of MTT assays. The developed paper-based sensor is easy-to-fabricate and portable, providing an effective platform for cellular H_2O_2 sensing and can be used to study the dynamic biological process involving H_2O_2 in biological and biomedical applications.

  10. International Catalogue of Sealed Radioactive Sources and Devices

    International Nuclear Information System (INIS)

    2010-01-01

    The international catalogue of sealed radioactive sources and devices have two major objectives. The first objective is to provide vital information for a wide range of individuals and organizations on industrially manufactured radioactive sources and devices. The second objective is to facilitate identification of design specifications based on limited information from orphan sources and devices to allow safe handling of these items.

  11. Multilevel electrochemical signal detections of metalloprotein heterolayers for bioelectronic device

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Yong-Ho; Yoo, Si-Youl; Lee, Taek [Department of Chemical and Biomolecular Engineering, Sogang University, 35 Baekbeom-ro(Sinsu-dong), Mapo-gu, Seoul 121-742 (Korea, Republic of); Lee, Hun Joo [Interdisciplinary Program of Integrated Biotechnology, Sogang University, 35 Baekbeomro(Sinsu-dong), Mapo-gu, Seoul 121-742 (Korea, Republic of); Min, Junhong [School of Integrative Engineering, Chung-Ang University, Heukseok-dong, Dongjak-gu, Seoul 156-756 (Korea, Republic of); Choi, Jeong-Woo, E-mail: jwchoi@sogang.ac.kr [Department of Chemical and Biomolecular Engineering, Sogang University, 35 Baekbeom-ro(Sinsu-dong), Mapo-gu, Seoul 121-742 (Korea, Republic of); Interdisciplinary Program of Integrated Biotechnology, Sogang University, 35 Baekbeomro(Sinsu-dong), Mapo-gu, Seoul 121-742 (Korea, Republic of)

    2014-01-31

    In the present study, we investigated the simultaneous detection of multilevel electrochemical signals from various metalloprotein heterolayers for the bioelectronic devices. A layer-by-layer assembly method based on simple electrostatic interaction was introduced to form protein bilayers. The gold substrate was modified with poly (ethylene glycol) thiol acid as the precursor, which introduced negative charges to the surface. Based on the isoelectric point, net-charge controlled metalloproteins by pH adjustment were sequentially immobilized on this negatively charged substrate. The degree of protein immobilization on the gold substrate was confirmed by surface plasmon resonance spectroscopy, and the surface topology changes due to the protein immobilization were confirmed by atomic force microscopy. Redox signals in the protein layers were measured by cyclic voltammetry. As a result, various redox signals generated from different metalloproteins on a single electrode were monitored. This proposed method for the detection of multi-level electrochemical signals can be directly applied to bioelectronic devices that store multi-information in a single electrode. - Highlights: • We fabricated heterolayers composed of various metalloproteins. • Metalloproteins were immobilized by layer-by-layer assembly. • The degree of immobilization was controlled by the net charge of metalloproteins. • Various redox signals generated from heterolayers were well monitored.

  12. Device for detecting the water leak within a feedwater nozzle in water cooled reactors

    International Nuclear Information System (INIS)

    Hattori, Tsunekazu.

    1984-01-01

    Purpose: To enable exact recognition and detection for the state of water leak. Constitution: The detection device comprises a thermocouple disposed to the outer surface of a feedwater nozzle, a distortion meter for detecting the change in the outer diameter of a nozzle and an acoustic emission generator disposed to the inside of the nozzle for generating a signal upon temperature change. These sensors previously monitor the states during normal operation, and thus detect the change in each of the states upon occurrence of water leakage to issue an alarm. (Kamimura, M.)

  13. HARDWARE TROJAN IDENTIFICATION AND DETECTION

    OpenAIRE

    Samer Moein; Fayez Gebali; T. Aaron Gulliver; Abdulrahman Alkandari

    2017-01-01

    ABSTRACT The majority of techniques developed to detect hardware trojans are based on specific attributes. Further, the ad hoc approaches employed to design methods for trojan detection are largely ineffective. Hardware trojans have a number of attributes which can be used to systematically develop detection techniques. Based on this concept, a detailed examination of current trojan detection techniques and the characteristics of existing hardware trojans is presented. This is used to dev...

  14. Nonlinear Optimization-Based Device-Free Localization with Outlier Link Rejection

    Directory of Open Access Journals (Sweden)

    Wendong Xiao

    2015-04-01

    Full Text Available Device-free localization (DFL is an emerging wireless technique for estimating the location of target that does not have any attached electronic device. It has found extensive use in Smart City applications such as healthcare at home and hospitals, location-based services at smart spaces, city emergency response and infrastructure security. In DFL, wireless devices are used as sensors that can sense the target by transmitting and receiving wireless signals collaboratively. Many DFL systems are implemented based on received signal strength (RSS measurements and the location of the target is estimated by detecting the changes of the RSS measurements of the wireless links. Due to the uncertainty of the wireless channel, certain links may be seriously polluted and result in erroneous detection. In this paper, we propose a novel nonlinear optimization approach with outlier link rejection (NOOLR for RSS-based DFL. It consists of three key strategies, including: (1 affected link identification by differential RSS detection; (2 outlier link rejection via geometrical positional relationship among links; (3 target location estimation by formulating and solving a nonlinear optimization problem. Experimental results demonstrate that NOOLR is robust to the fluctuation of the wireless signals with superior localization accuracy compared with the existing Radio Tomographic Imaging (RTI approach.

  15. Effects of low speed wind on the recognition/identification and pass-through communication tasks of auditory situation awareness afforded by military hearing protection/enhancement devices and tactical communication and protective systems.

    Science.gov (United States)

    Lee, Kichol; Casali, John G

    2016-01-01

    To investigate the effect of controlled low-speed wind-noise on the auditory situation awareness performance afforded by military hearing protection/enhancement devices (HPED) and tactical communication and protective systems (TCAPS). Recognition/identification and pass-through communications tasks were separately conducted under three wind conditions (0, 5, and 10 mph). Subjects wore two in-ear-type TCAPS, one earmuff-type TCAPS, a Combat Arms Earplug in its 'open' or pass-through setting, and an EB-15LE electronic earplug. Devices with electronic gain systems were tested under two gain settings: 'unity' and 'max'. Testing without any device (open ear) was conducted as a control. Ten subjects were recruited from the student population at Virginia Tech. Audiometric requirements were 25 dBHL or better at 500, 1000, 2000, 4000, and 8000 Hz in both ears. Performance on the interaction of communication task-by-device was significantly different only in 0 mph wind speed. The between-device performance differences varied with azimuthal speaker locations. It is evident from this study that stable (non-gusting) wind speeds up to 10 mph did not significantly degrade recognition/identification task performance and pass-through communication performance of the group of HPEDs and TCAPS tested. However, the various devices performed differently as the test sound signal speaker location was varied and it appears that physical as well as electronic features may have contributed to this directional result.

  16. Novel wearable-type biometric devices based on skin tissue optics with multispectral LED-photodiode matrix

    Science.gov (United States)

    Jo, Young Chang; Kim, Hae Na; Kang, Jae Hwan; Hong, Hyuck Ki; Choi, Yeon Shik; Jung, Suk Won; Kim, Sung Phil

    2017-04-01

    In this study, we examined the possibility of using a multispectral skin photomatrix (MSP) module as a novel biometric device. The MSP device measures optical patterns of the wrist skin tissue. Optical patterns consist of 2 × 8 photocurrent intensities of photodiode arrays, which are generated by optical transmission and diffuse reflection of photons from LED light sources with variable wavelengths into the wrist skin tissue. Optical patterns detected by the MSP device provide information on both the surface and subsurface characteristics of the human skin tissue. We found that in the 21 subjects we studied, they showed their unique characteristics, as determined using several wavelengths of light. The experimental results show that the best personal identification accuracy can be acquired using a combination of infrared light and yellow light. This novel biometric device, the MSP module, exhibited an excellent false acceptance rate (FAR) of 0.3% and a false rejection rate (FRR) of 0.0%, which are better than those of commercialized biometric devices such as a fingerprint biometric system. From these experimental results, we found that people exhibit unique optical patterns of their inner-wrist skin tissue and this uniqueness could be used for developing novel high-accuracy personal identification devices.

  17. Simulation and modeling for the stand-off radiation detection system (SORDS) using GEANT4

    Energy Technology Data Exchange (ETDEWEB)

    Hoover, Andrew S [Los Alamos National Laboratory; Wallace, Mark [Los Alamos National Laboratory; Galassi, Mark [Los Alamos National Laboratory; Mocko, Michal [Los Alamos National Laboratory; Palmer, David [Los Alamos National Laboratory; Schultz, Larry [Los Alamos National Laboratory; Tornga, Shawn [Los Alamos National Laboratory

    2009-01-01

    A Stand-Off Radiation Detection System (SORDS) is being developed through a joint effort by Raytheon, Los Alamos National Laboratory, Bubble Technology Industries, Radiation Monitoring Devices, and the Massachusetts Institute of Technology, for the Domestic Nuclear Detection Office (DNDO). The system is a mobile truck-based platform performing detection, imaging, and spectroscopic identification of gamma-ray sources. A Tri-Modal Imaging (TMI) approach combines active-mask coded aperture imaging, Compton imaging, and shadow imaging techniques. Monte Carlo simulation and modeling using the GEANT4 toolkit was used to generate realistic data for the development of imaging algorithms and associated software code.

  18. Development of corrosion condition sensing and monitoring system using radio-frequency identification devices (RFID)

    Energy Technology Data Exchange (ETDEWEB)

    Gu, G.P.; Zheng, W. [Natural Resources Canada, Ottawa, ON (Canada). CANMET Materials Technology Laboratory

    2008-05-15

    This study discussed the development of a corrosion sensing and monitoring system for military land vehicles. Radio-frequency identification device (RFID) technology uses radio waves to identify individual masses with RFID tags attached. A corrosion-sensing element was integrated with the RFID technology, which incorporated a galvanic corrosion cell designed to trigger RFID tags. Corrosion severity was then related to the galvanic current. The tag recorded the sensor reading and transmitted the data to an RFID reader. The tags consisted of a microchip and an antenna. A software development kit has also been developed to interface RFID data with existing applications. While it is currently not possible to modify the RFID tags to prevent security risks, further research is being conducted to assemble a data-logger system with corrosion probes to measure humidity, electrical resistance, and linear polarization resistance. Studies will also be conducted to assemble an active tag reader system and investigate potential modifications. 4 refs., 1 fig., 1 appendix.

  19. Charge coupled devices for detection of coherent neutrino-nucleus scattering

    Energy Technology Data Exchange (ETDEWEB)

    Fernandez Moroni, Guillermo; Estrada, Juan; Paolini, Eduardo E.; Cancelo, Gustavo; Tiffenberg, Javier; Molina, Jorge

    2015-04-01

    In this article the feasibility of using charge coupled devices (CCD) to detect low-energy neutrinos through their coherent scattering with nuclei is analyzed. The detection of neutrinos through this standard model process has been elusive because of the small energy deposited in such interaction. Typical particle detectors have thresholds of a few keV, and most of the energy deposition expected from coherent scattering is well below this level. The CCD detectors discussed in this paper can operate at a threshold of approximately 30 eV, making them ideal for observing this signal. On a CCD array of 500 g located next to a power nuclear reactor the number of coherent scattering events expected is about 3000 events/year. Our results shows that a detection with a confidence level of 99% can be reached within 16 days of continuous operation; with the current 52 g detector prototype this time lapse extends to five months.

  20. Digital-to-analog device for continuous detection of neutron damping decrement in logging

    International Nuclear Information System (INIS)

    Sokolov, Yu.I.; Zinchenko, A.I.; Rudenko, Eh.L.

    1976-01-01

    Algorithms are analyzed for a continuous detection of the damping decrement (DD) of the thermal neutron density in time, characterizing absorptive and diffusion properties of a bed; an an automated measuring device has been developed. The design of a digital calculator involving reguired mathematical and logical operations in the DD measurement by the specified algorithms necessitated the use of a system of elements with a diode-transistor RC logic. Following laboratory tests the mock-up of the calculator was subjected to borehole tests as part of the pulsed neutron logging apparatus of the IGN-4 type. A continuous detection of the DD reciprocal with a parallel recording of the differential and integral curves of pulsed neutron-neutron logging has been performed. The borehole tests revealed the efficiency of the new device and the possibility of its use together with the apparatus of the IGN-4 type

  1. Simultaneous detection and identification of Aspergillus and mucorales species in tissues collected from patients with fungal rhinosinusitis.

    Science.gov (United States)

    Zhao, Zuotao; Li, Lili; Wan, Zhe; Chen, Wei; Liu, Honggang; Li, Ruoyu

    2011-04-01

    Rapid detection and differentiation of Aspergillus and Mucorales species in fungal rhinosinusitis diagnosis are desirable, since the clinical management and prognosis associated with the two taxa are fundamentally different. We describe an assay based on a combination of broad-range PCR amplification and reverse line blot hybridization (PCR/RLB) to detect and differentiate the pathogens causing fungal rhinosinusitis, which include five Aspergillus species (A. fumigatus, A. flavus, A. niger, A. terreus, and A. nidulans) and seven Mucorales species (Mucor heimalis, Mucor racemosus, Mucor cercinelloidea, Rhizopus arrhizus, Rhizopus microsporus, Rhizomucor pusillus, and Absidia corymbifera). The assay was validated with 98 well-characterized clinical isolates and 41 clinical tissue specimens. PCR/RLB showed high sensitivity and specificity, with 100% correct identifications of 98 clinical isolates and no cross-hybridization between the species-specific probes. Results for five control isolates, Candida albicans, Fusarium solani, Scedosporium apiospermum, Penicillium marneffei, and Exophiala verrucosa, were negative as judged by PCR/RLB. The analytical sensitivity of PCR/RLB was found to be 1.8 × 10(-3) ng/μl by 10-fold serial dilution of Aspergillus genomic DNA. The assay identified 35 of 41 (85.4%) clinical specimens, exhibiting a higher sensitivity than fungal culture (22 of 41; 53.7%) and direct sequencing (18 of 41; 43.9%). PCR/RLB similarly showed high specificity, with correct identification 16 of 18 specimens detected by internal transcribed spacer (ITS) sequencing and 16 of 22 detected by fungal culture, but it also has the additional advantage of being able to detect mixed infection in a single clinical specimen. The PCR/RLB assay thus provides a rapid and reliable option for laboratory diagnosis of fungal rhinosinusitis.

  2. Simultaneous Detection and Identification of Aspergillus and Mucorales Species in Tissues Collected from Patients with Fungal Rhinosinusitis▿

    Science.gov (United States)

    Zhao, Zuotao; Li, Lili; Wan, Zhe; Chen, Wei; Liu, Honggang; Li, Ruoyu

    2011-01-01

    Rapid detection and differentiation of Aspergillus and Mucorales species in fungal rhinosinusitis diagnosis are desirable, since the clinical management and prognosis associated with the two taxa are fundamentally different. We describe an assay based on a combination of broad-range PCR amplification and reverse line blot hybridization (PCR/RLB) to detect and differentiate the pathogens causing fungal rhinosinusitis, which include five Aspergillus species (A. fumigatus, A. flavus, A. niger, A. terreus, and A. nidulans) and seven Mucorales species (Mucor heimalis, Mucor racemosus, Mucor cercinelloidea, Rhizopus arrhizus, Rhizopus microsporus, Rhizomucor pusillus, and Absidia corymbifera). The assay was validated with 98 well-characterized clinical isolates and 41 clinical tissue specimens. PCR/RLB showed high sensitivity and specificity, with 100% correct identifications of 98 clinical isolates and no cross-hybridization between the species-specific probes. Results for five control isolates, Candida albicans, Fusarium solani, Scedosporium apiospermum, Penicillium marneffei, and Exophiala verrucosa, were negative as judged by PCR/RLB. The analytical sensitivity of PCR/RLB was found to be 1.8 × 10−3 ng/μl by 10-fold serial dilution of Aspergillus genomic DNA. The assay identified 35 of 41 (85.4%) clinical specimens, exhibiting a higher sensitivity than fungal culture (22 of 41; 53.7%) and direct sequencing (18 of 41; 43.9%). PCR/RLB similarly showed high specificity, with correct identification 16 of 18 specimens detected by internal transcribed spacer (ITS) sequencing and 16 of 22 detected by fungal culture, but it also has the additional advantage of being able to detect mixed infection in a single clinical specimen. The PCR/RLB assay thus provides a rapid and reliable option for laboratory diagnosis of fungal rhinosinusitis. PMID:21325541

  3. 21 CFR 820.60 - Identification.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Identification. 820.60 Section 820.60 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES QUALITY SYSTEM REGULATION Identification and Traceability § 820.60 Identification. Each manufacturer shall...

  4. Field Prototype of the ENEA Neutron Active Interrogation Device for the Detection of Dirty Bombs

    Directory of Open Access Journals (Sweden)

    Nadia Cherubini

    2016-10-01

    Full Text Available The Italian National Agency for New Technologies, Energy, and Sustainable Economic Development (ENEA Neutron Active Interrogation (NAI device is a tool designed to improve CBRNE defense. It is designed to uncover radioactive and nuclear threats including those in the form of Improvised Explosive Devices (IEDs, the so-called “dirty bombs”. The NAI device, at its current development stage, allows to detect 6 g of 235U hidden in a package. It is easily transportable, light in weight, and with a real-time response. Its working principle is based on two stages: (1 an “active” stage in which neutrons are emitted by a neutron generator to interact with the item under inspection, and (2 a “passive” stage in which secondary neutrons are detected originating a signal that, once processed, allows recognition of the offence. In particular, a clear indication of the potential threat is obtained by a dedicated software based on the Differential Die-Away Time Analysis method.

  5. A novel screen-printed microfluidic paper-based electrochemical device for detection of glucose and uric acid in urine.

    Science.gov (United States)

    Yao, Yong; Zhang, Chunsun

    2016-10-01

    A novel screen-printed microfluidic paper-based analytical device with all-carbon electrode-enabled electrochemical assay (SP-ACE-EC-μPAD) has been developed. The fabrication of these devices involved wax screen-printing, which was simple, low-cost and energy-efficient. The working, counter and reference electrodes were screen-printed using carbon ink on the patterned paper devices. Different wax screen-printing processes were examined and optimized, which led to an improved method with a shorter heating time (~5 s) and a lower heating temperature (75 °C). Different printing screens were examined, with a 300-mesh polyester screen yielding the highest quality wax screen-prints. The carbon electrodes were screen-printed on the μPADs and then examined using cyclic voltammetry. The analytical performance of the SP-ACE-EC-μPADs for the detection of glucose and uric acid in standard solutions was investigated. The results were reproducible, with a linear relationship [R(2) = 0.9987 (glucose) or 0.9997 (uric acid)] within the concentration range of interest, and with detection limits as low as 0.35 mM (glucose) and 0.08 mM (uric acid). To determine the clinical utility of the μPADs, chronoamperometry was used to analyze glucose and uric acid in real urine samples using the standard addition method. Our devices were able to detect the analytes of interest in complex real-world biological samples, and have the potential for use in a wide variety of applications.

  6. Detective studies of soft X-ray tomography on controlled thermonuclear fusion device

    International Nuclear Information System (INIS)

    Li Linzhong; Su Fei

    2004-01-01

    In is necessary to design tomographic detective system with very high accuracy and high quality. It is such a detective system that its five resolutions are all very high quality. The five resolutions are: the radial resolution, the angular resolution, the spatial resolution of detector, the resolution of detector array, and the time resolution. The radial resolution is decided by the number of detectors in detector array. The angular resolutions depend on the number of detector arrays. According to the concrete condition of controlled device, through making special rectangular detector the optimum spatial resolution of detector and the optimum spatial resolution of detector array can be obtained. The high time resolution can be got by making wide-band ampli-filter circuit system. The tomographic system with high quality can use the multi-angle multi-array mode or perfect single array mode. The soft X-ray tomographic system with high sensitivity can measure the stable signal and perform the tomography under the conditions of Te ∼150 eV, ne ∼1013 cm-3 on the small Tokamak devices. (authors)

  7. Full On-Device Stay Points Detection in Smartphones for Location-Based Mobile Applications

    Directory of Open Access Journals (Sweden)

    Rafael Pérez-Torres

    2016-10-01

    Full Text Available The tracking of frequently visited places, also known as stay points, is a critical feature in location-aware mobile applications as a way to adapt the information and services provided to smartphones users according to their moving patterns. Location based applications usually employ the GPS receiver along with Wi-Fi hot-spots and cellular cell tower mechanisms for estimating user location. Typically, fine-grained GPS location data are collected by the smartphone and transferred to dedicated servers for trajectory analysis and stay points detection. Such Mobile Cloud Computing approach has been successfully employed for extending smartphone’s battery lifetime by exchanging computation costs, assuming that on-device stay points detection is prohibitive. In this article, we propose and validate the feasibility of having an alternative event-driven mechanism for stay points detection that is executed fully on-device, and that provides higher energy savings by avoiding communication costs. Our solution is encapsulated in a sensing middleware for Android smartphones, where a stream of GPS location updates is collected in the background, supporting duty cycling schemes, and incrementally analyzed following an event-driven paradigm for stay points detection. To evaluate the performance of the proposed middleware, real world experiments were conducted under different stress levels, validating its power efficiency when compared against a Mobile Cloud Computing oriented solution.

  8. Sensitive paper-based analytical device for fast colorimetric detection of nitrite with smartphone.

    Science.gov (United States)

    Zhang, Xiu-Xiu; Song, Yi-Zhen; Fang, Fang; Wu, Zhi-Yong

    2018-04-01

    On-site rapid monitoring of nitrite as an assessment indicator of the environment, food, and physiological systems has drawn extensive attention. Here, electrokinetic stacking (ES) was combined with colorimetric reaction on a paper-based device (PAD) to achieve colorless nitrite detection with smartphone. In this paper, nitrite was stacked on the paper fluidic channel as a narrow band by electrokinetic stacking. Then, Griess reagent was introduced to visualize the stacking band. Under optimal conditions, the sensitivity of nitrite was 160-fold increased within 5 min. A linear response in the range of 0.075 to 1.0 μg mL -1 (R 2  = 0.99) and a limit of detection (LOD) of 73 ng mL -1 (0.86 μM) were obtained. The LOD was 10 times lower than the reported PAD, and close to that achieved by a desktop spectrophotometer. The applicability was demonstrated by nitrite detection from saliva and water with good selectivity, adding 100 times more concentrated co-ions. High recovery (91.0~108.7%) and reasonable intra-day and inter-day reproducibility (RSD work shows that the sensitivity of colorless analyte detection-based colorimetric reaction can be effectively enhanced by integration of ES on a PAD. Graphical abstract Schematic of the experimental setups (left) and the corresponding images (right) of the actual portable device.

  9. Full On-Device Stay Points Detection in Smartphones for Location-Based Mobile Applications.

    Science.gov (United States)

    Pérez-Torres, Rafael; Torres-Huitzil, César; Galeana-Zapién, Hiram

    2016-10-13

    The tracking of frequently visited places, also known as stay points, is a critical feature in location-aware mobile applications as a way to adapt the information and services provided to smartphones users according to their moving patterns. Location based applications usually employ the GPS receiver along with Wi-Fi hot-spots and cellular cell tower mechanisms for estimating user location. Typically, fine-grained GPS location data are collected by the smartphone and transferred to dedicated servers for trajectory analysis and stay points detection. Such Mobile Cloud Computing approach has been successfully employed for extending smartphone's battery lifetime by exchanging computation costs, assuming that on-device stay points detection is prohibitive. In this article, we propose and validate the feasibility of having an alternative event-driven mechanism for stay points detection that is executed fully on-device, and that provides higher energy savings by avoiding communication costs. Our solution is encapsulated in a sensing middleware for Android smartphones, where a stream of GPS location updates is collected in the background, supporting duty cycling schemes, and incrementally analyzed following an event-driven paradigm for stay points detection. To evaluate the performance of the proposed middleware, real world experiments were conducted under different stress levels, validating its power efficiency when compared against a Mobile Cloud Computing oriented solution.

  10. Rapid detection of Cu(2+) by a paper-based microfluidic device coated with bovine serum albumin (BSA)-Au nanoclusters.

    Science.gov (United States)

    Fang, Xueen; Zhao, Qianqian; Cao, Hongmei; Liu, Juan; Guan, Ming; Kong, Jilie

    2015-11-21

    In this work, bovine serum albumin (BSA)-Au nanoclusters were used to coat a paper-based microfluidic device. This device acted as a Cu(2+) biosensor that showed fluorescence quenching on detection of copper ions. The detection limit of this sensor could be adjusted by altering the water absorbing capacity of the device. Qualitative and semi-quantitative results could be obtained visually without the aid of any advanced instruments. This sensor could test Cu(2+) rapidly with high specificity and sensitivity, which would be useful for point-of-care testing (POCT).

  11. DNA detection and single nucleotide mutation identification using SERS for molecular diagnostics and global health

    Science.gov (United States)

    Ngo, Hoan T.; Gandra, Naveen; Fales, Andrew M.; Taylor, Steve M.; Vo-Dinh, Tuan

    2017-02-01

    Nucleic acid-based molecular diagnostics at the point-of-care (POC) and in resource-limited settings is still a challenge. We present a sensitive yet simple DNA detection method with single nucleotide polymorphism (SNP) identification capability. The detection scheme involves sandwich hybridization of magnetic beads conjugated with capture probes, target sequences, and ultrabright surface-enhanced Raman Scattering (SERS) nanorattles conjugated with reporter probes. Upon hybridization, the sandwich probes are concentrated at the detection focus controlled by a magnetic system for SERS measurements. The ultrabright SERS nanorattles, consisting of a core and a shell with resonance Raman reporters loaded in the gap space between the core and the shell, serve as SERS tags for ultrasensitive signal detection. Specific DNA sequences of the malaria parasite Plasmodium falciparum and dengue virus 1 (DENV1) were used as the model marker system. Detection limit of approximately 100 attomoles was achieved. Single nucleotide polymorphism (SNP) discrimination of wild type malaria DNA and mutant malaria DNA, which confers resistance to artemisinin drugs, was also demonstrated. The results demonstrate the molecular diagnostic potential of the nanorattle-based method to both detect and genotype infectious pathogens. The method's simplicity makes it a suitable candidate for molecular diagnosis at the POC and in resource-limited settings.

  12. Home-made Detection Device for a Mixture of Ethanol and Acetone

    Directory of Open Access Journals (Sweden)

    Sukon Phanichphant

    2007-02-01

    Full Text Available A device for the detection and determination of ethanol and acetone wasconstructed, consisting of a packed column, a chamber with a sensor head, 2 dc powersupplies, a multimeter and a computer. A commercially available TGS 822 detector head(Figaro Company Limited was used as the sensor head. The TGS 822 detector consists of aSnO2 thick film deposited on the surface of an alumina ceramic tube which contains aheating element inside. An analytical column was coupled with the setup to enhance theseparation of ethanol and acetone before they reached the sensor head. Optimum systemconditions for detection of ethanol and acetone were achieved by varying the flow rate of thecarrier gas, voltage of the heating coil (VH, voltage of the circuit sensor (VC, loadresistance of the circuit sensor (RL and the injector port temperature. The flow of the carriergas was 15 mL/min; the circuit conditions were VH = 5.5 V, VC = 20 V, RL = 68 k ; and theinjection port temperature was 150°C. Under these conditions the retention times (tR forethanol and acetone were 1.95 and 0.57 minutes, respectively. Calibration graphs wereobtained for ethanol and acetone over the concentration range of 10 to 160 mg/L. The limitsof detection (LOD for ethanol and acetone were 9.25 mg/L and 4.41 mg/L respectively.

  13. Digital micromirror devices in Raman trace detection of explosives

    Science.gov (United States)

    Glimtoft, Martin; Svanqvist, Mattias; Ågren, Matilda; Nordberg, Markus; Östmark, Henric

    2016-05-01

    Imaging Raman spectroscopy based on tunable filters is an established technique for detecting single explosives particles at stand-off distances. However, large light losses are inherent in the design due to sequential imaging at different wavelengths, leading to effective transmission often well below 1 %. The use of digital micromirror devices (DMD) and compressive sensing (CS) in imaging Raman explosives trace detection can improve light throughput and add significant flexibility compared to existing systems. DMDs are based on mature microelectronics technology, and are compact, scalable, and can be customized for specific tasks, including new functions not available with current technologies. This paper has been focusing on investigating how a DMD can be used when applying CS-based imaging Raman spectroscopy on stand-off explosives trace detection, and evaluating the performance in terms of light throughput, image reconstruction ability and potential detection limits. This type of setup also gives the possibility to combine imaging Raman with non-spatially resolved fluorescence suppression techniques, such as Kerr gating. The system used consists of a 2nd harmonics Nd:YAG laser for sample excitation, collection optics, DMD, CMOScamera and a spectrometer with ICCD camera for signal gating and detection. Initial results for compressive sensing imaging Raman shows a stable reconstruction procedure even at low signals and in presence of interfering background signal. It is also shown to give increased effective light transmission without sacrificing molecular specificity or area coverage compared to filter based imaging Raman. At the same time it adds flexibility so the setup can be customized for new functionality.

  14. 21 CFR 882.5940 - Electroconvulsive therapy device.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Electroconvulsive therapy device. 882.5940 Section 882.5940 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... Electroconvulsive therapy device. (a) Identification. An electroconvulsive therapy device is a device used for...

  15. A Lab on a chip device for rapid identification of Avian Influenza virus by on-chip sample preparation and solid phase PCR

    DEFF Research Database (Denmark)

    Yi, Sun; Dhumpa, Raghuram; Bang, Dang Duong

    2009-01-01

    In this paper, we describe a novel lab-on-a-chip device for fast AIV screening by integrating DNA microarray-based solid phase PCR on microchip. The device can handle viral samples in an automatic way. Moreover, multiplex PCR and sequence detection are done in one-step, which greatly simplifies...

  16. The combined rapid detection and species-level identification of yeasts in simulated blood culture using a colorimetric sensor array.

    Science.gov (United States)

    Shrestha, Nabin K; Lim, Sung H; Wilson, Deborah A; SalasVargas, Ana Victoria; Churi, Yair S; Rhodes, Paul A; Mazzone, Peter J; Procop, Gary W

    2017-01-01

    A colorimetric sensor array (CSA) has been demonstrated to rapidly detect and identify bacteria growing in blood cultures by obtaining a species-specific "fingerprint" of the volatile organic compounds (VOCs) produced during growth. This capability has been demonstrated in prokaryotes, but has not been reported for eukaryotic cells growing in culture. The purpose of this study was to explore if a disposable CSA could differentially identify 7 species of pathogenic yeasts growing in blood culture. Culture trials of whole blood inoculated with a panel of clinically important pathogenic yeasts at four different microorganism loads were performed. Cultures were done in both standard BacT/Alert and CSA-embedded bottles, after adding 10 mL of spiked blood to each bottle. Color changes in the CSA were captured as images by an optical scanner at defined time intervals. The captured images were analyzed to identify the yeast species. Time to detection by the CSA was compared to that in the BacT/Alert system. One hundred sixty-two yeast culture trials were performed, including strains of several species of Candida (Ca. albicans, Ca. glabrata, Ca. parapsilosis, and Ca. tropicalis), Clavispora (synonym Candida) lusitaniae, Pichia kudriavzevii (synonym Candida krusei) and Cryptococcus neoformans, at loads of 8.2 × 105, 8.3 × 103, 8.5 × 101, and 1.7 CFU/mL. In addition, 8 negative trials (no yeast) were conducted. All negative trials were correctly identified as negative, and all positive trials were detected. Colorimetric responses were species-specific and did not vary by inoculum load over the 500000-fold range of loads tested, allowing for accurate species-level identification. The mean sensitivity for species-level identification by CSA was 74% at detection, and increased with time, reaching almost 95% at 4 hours after detection. At an inoculum load of 1.7 CFU/mL, mean time to detection with the CSA was 6.8 hours (17%) less than with the BacT/Alert platform. The CSA

  17. 40 CFR Table 6 to Subpart IIIii of... - Examples of Techniques for Equipment Problem Identification, Leak Detection and Mercury Vapor

    Science.gov (United States)

    2010-07-01

    ... Problem Identification, Leak Detection and Mercury Vapor 6 Table 6 to Subpart IIIII of Part 63 Protection... Hazardous Air Pollutants: Mercury Emissions From Mercury Cell Chlor-Alkali Plants Pt. 63, Subpt. IIIII..., Leak Detection and Mercury Vapor As stated in Tables 1 and 2 of Subpart IIIII, examples of techniques...

  18. Novel Wearable Device for Blood Leakage Detection during Hemodialysis Using an Array Sensing Patch.

    Science.gov (United States)

    Du, Yi-Chun; Lim, Bee-Yen; Ciou, Wei-Siang; Wu, Ming-Jui

    2016-06-09

    Hemodialysis (HD) is a clinical treatment that requires the puncturing of the body surface. However, needle dislodgement can cause a high risk of blood leakage and can be fatal to patients. Previous studies proposed several devices for blood leakage detection using optical or electrical techniques. Nonetheless, these methods used single-point detection and the design was not suitable for multi-bed monitoring. This study proposed a novel wearable device for blood leakage monitoring during HD using an array sensing patch. The array sensing patch combined with a mapping circuit and a wireless module could measure and transmit risk levels. The different risk levels could improve the working process of healthcare workers, and enhance their work efficiency and reduce inconvenience due to false alarms. Experimental results showed that each point of the sensing array could detect up to 0.1 mL of blood leakage and the array sensing patch supports a risk level monitoring system up to 8 h to alert healthcare personnel of pertinent danger to the patients.

  19. Novel Wearable Device for Blood Leakage Detection during Hemodialysis Using an Array Sensing Patch

    Directory of Open Access Journals (Sweden)

    Yi-Chun Du

    2016-06-01

    Full Text Available Hemodialysis (HD is a clinical treatment that requires the puncturing of the body surface. However, needle dislodgement can cause a high risk of blood leakage and can be fatal to patients. Previous studies proposed several devices for blood leakage detection using optical or electrical techniques. Nonetheless, these methods used single-point detection and the design was not suitable for multi-bed monitoring. This study proposed a novel wearable device for blood leakage monitoring during HD using an array sensing patch. The array sensing patch combined with a mapping circuit and a wireless module could measure and transmit risk levels. The different risk levels could improve the working process of healthcare workers, and enhance their work efficiency and reduce inconvenience due to false alarms. Experimental results showed that each point of the sensing array could detect up to 0.1 mL of blood leakage and the array sensing patch supports a risk level monitoring system up to 8 h to alert healthcare personnel of pertinent danger to the patients.

  20. Detection and identification of Leishmania spp.: application of two hsp70-based PCR-RFLP protocols to clinical samples from the New World.

    Science.gov (United States)

    Montalvo, Ana M; Fraga, Jorge; Tirado, Dídier; Blandón, Gustavo; Alba, Annia; Van der Auwera, Gert; Vélez, Iván Darío; Muskus, Carlos

    2017-07-01

    Leishmaniasis is highly prevalent in New World countries, where several methods are available for detection and identification of Leishmania spp. Two hsp70-based PCR protocols (PCR-N and PCR-F) and their corresponding restriction fragment length polymorphisms (RFLP) were applied for detection and identification of Leishmania spp. in clinical samples recruited in Colombia, Guatemala, and Honduras. A total of 93 cases were studied. The samples were classified into positive or suspected of leishmaniasis according to parasitological criteria. Molecular amplification of two different hsp70 gene fragments and further RFLP analysis for identification of Leishmania species was done. The detection in parasitologically positive samples was higher using PCR-N than PCR-F. In the total of samples studied, the main species identified were Leishmania panamensis, Leishmania braziliensis, and Leishmania infantum (chagasi). Although RFLP-N was more efficient for the identification, RFLP-F is necessary for discrimination between L. panamensis and Leishmania guyanesis, of great importance in Colombia. Unexpectedly, one sample from this country revealed an RFLP pattern corresponding to Leishmania naiffi. Both molecular variants are applicable for the study of clinical samples originated in Colombia, Honduras, and Guatemala. Choosing the better tool for each setting depends on the species circulating. More studies are needed to confirm the presence of L. naiffi in Colombian territory.

  1. Process and device for detecting and localizing leaks in a tube bundle heat exchanger when it is stopped

    International Nuclear Information System (INIS)

    Germain, J.L.; Jeanneteau, E.; Loisy, F.

    1986-01-01

    The device can be used to detect the tubes presenting leaks in a tube bundle exchanger of a light water reactor. This device comprises a feeding point to fill the secondary part of the exchanger, in which the tubes are immersed, with a pressure mixture of vector gas (air) and helium. It has also a feeding point to establish in the tube a sweeping air flow. An analysis apparatus, such as a spectrograph, measures the helium content of air at the outlet of each tube [fr

  2. MISENS DEVICE AS A NEW AUTOMATED BIOSENSING PLATFORM BASED ON REAL-TIME ELECTROCHEMICAL PROFILING (REP

    Directory of Open Access Journals (Sweden)

    yıldız uludağ

    2016-09-01

    Full Text Available In various fields like health, environmental control, food security and military defense; there is an increasing demand for on-site detection, fast identification and urgent response which brings the necessity to employ laboratory detection procedures on standalone automatic devices. In response to that TUBITAK BILGEM’s Bioelectronic Devices and Systems Group has been developing portable and fully automated biosensor devices using optical and electrochemical biosensor detection techniques. Here we describe a new integrated and fully automated lab-on-a-chip based biosensor device ‘MiSens’. The key features of the MiSens include a new electrode array, an integrated microfluidic system and real-time amperometric measurements during the flow of enzyme substrate. While simple protocols can be controlled from the LCD display on the device, other main device control procedures can be run wireless by a tablet/PC using the MiCont™ software developed by the team. For the device, a new plug and play type sensor chip docking station has been designed that with one move it enables the formation of a ~ 7-10 µl capacity flow cell on the electrode array with the necessary microfluidic and electronic connections. The MiSens device has been developed by our multi-disciplinary team by integrating and automatising the earlier developed sensing platform REP™ (Real-time Electrochemical Profiling. The performance of the MiSens device has been tested using cyclic voltammetry and amperometry tests and the results were compared with an of the shelf potantiostat.

  3. Early Detection and Identification of Anomalies in Chemical Regime

    International Nuclear Information System (INIS)

    Figedy, Stefan; Smiesko, Ivan

    2011-01-01

    This paper provides a brief information about the basic features of a newly developed diagnostic system for early detection and identification of anomalies incoming in the water chemistry regime of the primary and secondary circuit of VVER-440 reactor. This system, called SACHER (System of Analysis of CHEmical Regime) is being installed within the major modernization project at the NPP-V2 Bohunice in the Slovak Republic. System SACHER has been developed fully in MATLAB environment. The availability of prompt information about the chemical conditions of the primary and secondary circuit is very important to prevent the undue corrosion and deposit build-up. The typical chemical information systems that exist and work at the NPPs give the user values of the measured quantities together with their time trends and other derived values. It is then the experienced user's role to recognize the situation the monitored process is in and make the subsequent decisions and take the measures. The SACHER system, based on the computational intelligence techniques, inserts the elements of intelligence into the overall chemical information system. It has the modular structure with the following most important modules: normality module- its aim is to recognize that the process starts to deviate from the normal one and serves as the early warning to the staff to take the adequate measures, fuzzy identification module- its aim is to identify the anomaly on the basis of a set of fuzzy rules, time-prediction module- its aim is to predict the behavior/trend of selected chemical quantities 8 hours ahead in 15 min step from the moment of request, validation module- its aim is to validate the measured quantities, trend module- this module serves for showing the trends of the acquired quantities

  4. Device for detecting the specific gravity of a liquid. [Patent application

    Science.gov (United States)

    Derouin, C.R.; Kerwin, W.J.; McCormick, J.B.; Bobbett, R.E.

    1980-11-18

    A device for detecting the specific gravity of a liquid and a device for detecting the state of charge of a liquid phase electrolyte battery are described. In one embodiment of the present invention, a change in the critical angle of total internal reflection is utilized to determine the index of refraction of the liquid to be measured. It is shown that the index of refraction of the liquid is a function of the specific gravity of the liquid. In applications for measuring the state of charge of a battery, the specific gravity is proportional to the state of charge of the battery. A change in intensity of rays intersecting an interface surface indicates the critical angle which is a direct indication of the specific gravity of the liquid and the state of charge of a battery. In another embodiment, a light beam is projected through a transparent medium and then through a portion of the liquid to be measured. A change in refraction due to a change in the index of refraction of the liquid produces a deflection of the beam which is measured by a detector. The magnitude of deflection of the beam is directly proportional to the specific gravity of the liquid and the state of charge of a battery.

  5. A novel copro-diagnostic molecular method for qualitative detection and identification of parasitic nematodes in amphibians and reptiles.

    Directory of Open Access Journals (Sweden)

    Lucas G Huggins

    Full Text Available Anthropogenic disturbance via resource acquisition, habitat fragmentation and climate change, amongst other factors, has led to catastrophic global biodiversity losses and species extinctions at an accelerating rate. Amphibians are currently one of the worst affected classes with at least a third of species categorised as being threatened with extinction. At the same time, they are also critically important for many habitats and provide man with a powerful proxy for ecosystem health by acting as a bioindicator group. Whilst the causes of synchronised amphibian losses are varied recent research has begun to highlight a growing role that macroparasites are playing in amphibian declines. However, diagnosing parasite infection in the field can be problematic, principally relying on collection and euthanasia of hosts, followed by necropsy and morphological identification of parasites in situ. The current study developed a non-invasive PCR-based methodology for sensitive detection and identification of parasitic nematode DNA released in the faeces of infected amphibians as egg or tissue fragments (environmental DNA. A DNA extraction protocol optimised for liberation of DNA from resilient parasite eggs was developed alongside the design of a novel, nematode universal, degenerate primer pair, thus avoiding the difficulties of using species specific primers in situations where common parasite species are unknown. Used in conjunction this protocol and primer pair was tested on a wide range of faecal samples from captive and wild amphibians. The primers and protocol were validated and detected infections, including a Railletnema nematode infection in poison dart frogs from ZSL London Zoo and Mantella cowani frogs in the wild. Furthermore, we demonstrate the efficacy of our PCR-based protocol for detecting nematode infection in other hosts, such as the presence of pinworm (Aspiculuris in two tortoise species and whipworm (Trichuris muris in mice. Our

  6. A novel copro-diagnostic molecular method for qualitative detection and identification of parasitic nematodes in amphibians and reptiles.

    Science.gov (United States)

    Huggins, Lucas G; Michaels, Christopher J; Cruickshank, Sheena M; Preziosi, Richard F; Else, Kathryn J

    2017-01-01

    Anthropogenic disturbance via resource acquisition, habitat fragmentation and climate change, amongst other factors, has led to catastrophic global biodiversity losses and species extinctions at an accelerating rate. Amphibians are currently one of the worst affected classes with at least a third of species categorised as being threatened with extinction. At the same time, they are also critically important for many habitats and provide man with a powerful proxy for ecosystem health by acting as a bioindicator group. Whilst the causes of synchronised amphibian losses are varied recent research has begun to highlight a growing role that macroparasites are playing in amphibian declines. However, diagnosing parasite infection in the field can be problematic, principally relying on collection and euthanasia of hosts, followed by necropsy and morphological identification of parasites in situ. The current study developed a non-invasive PCR-based methodology for sensitive detection and identification of parasitic nematode DNA released in the faeces of infected amphibians as egg or tissue fragments (environmental DNA). A DNA extraction protocol optimised for liberation of DNA from resilient parasite eggs was developed alongside the design of a novel, nematode universal, degenerate primer pair, thus avoiding the difficulties of using species specific primers in situations where common parasite species are unknown. Used in conjunction this protocol and primer pair was tested on a wide range of faecal samples from captive and wild amphibians. The primers and protocol were validated and detected infections, including a Railletnema nematode infection in poison dart frogs from ZSL London Zoo and Mantella cowani frogs in the wild. Furthermore, we demonstrate the efficacy of our PCR-based protocol for detecting nematode infection in other hosts, such as the presence of pinworm (Aspiculuris) in two tortoise species and whipworm (Trichuris muris) in mice. Our environmental DNA

  7. Aircraft Abnormal Conditions Detection, Identification, and Evaluation Using Innate and Adaptive Immune Systems Interaction

    Science.gov (United States)

    Al Azzawi, Dia

    Abnormal flight conditions play a major role in aircraft accidents frequently causing loss of control. To ensure aircraft operation safety in all situations, intelligent system monitoring and adaptation must rely on accurately detecting the presence of abnormal conditions as soon as they take place, identifying their root cause(s), estimating their nature and severity, and predicting their impact on the flight envelope. Due to the complexity and multidimensionality of the aircraft system under abnormal conditions, these requirements are extremely difficult to satisfy using existing analytical and/or statistical approaches. Moreover, current methodologies have addressed only isolated classes of abnormal conditions and a reduced number of aircraft dynamic parameters within a limited region of the flight envelope. This research effort aims at developing an integrated and comprehensive framework for the aircraft abnormal conditions detection, identification, and evaluation based on the artificial immune systems paradigm, which has the capability to address the complexity and multidimensionality issues related to aircraft systems. Within the proposed framework, a novel algorithm was developed for the abnormal conditions detection problem and extended to the abnormal conditions identification and evaluation. The algorithm and its extensions were inspired from the functionality of the biological dendritic cells (an important part of the innate immune system) and their interaction with the different components of the adaptive immune system. Immunity-based methodologies for re-assessing the flight envelope at post-failure and predicting the impact of the abnormal conditions on the performance and handling qualities are also proposed and investigated in this study. The generality of the approach makes it applicable to any system. Data for artificial immune system development were collected from flight tests of a supersonic research aircraft within a motion-based flight

  8. 21 CFR 892.2040 - Medical image hardcopy device.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Medical image hardcopy device. 892.2040 Section... (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.2040 Medical image hardcopy device. (a) Identification. A medical image hardcopy device is a device that produces a visible printed record of a medical...

  9. Dynamic detection of spin accumulation in ferromagnet-semiconductor devices by ferromagnetic resonance (Conference Presentation)

    Science.gov (United States)

    Crowell, Paul A.; Liu, Changjiang; Patel, Sahil; Peterson, Tim; Geppert, Chad C.; Christie, Kevin; Stecklein, Gordon; Palmstrøm, Chris J.

    2016-10-01

    A distinguishing feature of spin accumulation in ferromagnet-semiconductor devices is its precession in a magnetic field. This is the basis for detection techniques such as the Hanle effect, but these approaches become ineffective as the spin lifetime in the semiconductor decreases. For this reason, no electrical Hanle measurement has been demonstrated in GaAs at room temperature. We show here that by forcing the magnetization in the ferromagnet to precess at resonance instead of relying only on the Larmor precession of the spin accumulation in the semiconductor, an electrically generated spin accumulation can be detected up to 300 K. The injection bias and temperature dependence of the measured spin signal agree with those obtained using traditional methods. We further show that this new approach enables a measurement of short spin lifetimes (C. Liu, S. J. Patel, T. A. Peterson, C. C. Geppert, K. D. Christie, C. J. Palmstrøm, and P. A. Crowell, "Dynamic detection of electron spin accumulation in ferromagnet-semiconductor devices by ferromagnetic resonance," Nature Communications 7, 10296 (2016). http://dx.doi.org/10.1038/ncomms10296

  10. Rapid detection and identification of Bacillus anthracis in food using pyrosequencing technology.

    Science.gov (United States)

    Amoako, Kingsley K; Janzen, Timothy W; Shields, Michael J; Hahn, Kristen R; Thomas, Matthew C; Goji, Noriko

    2013-08-01

    The development of advanced methodologies for the detection of Bacillus anthracis has been evolving rapidly since the release of the anthrax spores in the mail in 2001. Recent advances in detection and identification techniques could prove to be an essential component in the defense against biological attacks. Sequence based such as pyrosequencing, which has the capability to determine short DNA stretches in real-time using biotinylated PCR amplicons, has potential biodefense applications. Using markers from the virulence plasmids (pXO1 and pXO2) and chromosomal regions, we have demonstrated the power of this technology in the rapid, specific and sensitive detection of B. anthracis spores in food matrices including milk, juice, bottled water, and processed meat. The combined use of immunomagnetic separation and pyrosequencing showed positive detection when liquid foods (bottled water, milk, juice), and processed meat were experimentally inoculated with 6CFU/mL and 6CFU/g, respectively, without an enrichment step. Pyrosequencing is completed in about 60min (following PCR amplification) and yields accurate and reliable results with an added layer of confidence. The entire assay (from sample preparation to sequencing information) can be completed in about 7.5h. A typical run on food samples yielded 67-80bp reads with 94-100% identity to the expected sequence. This sequence based approach is a novel application for the detection of anthrax spores in food with potential application in foodborne bioterrorism response and biodefense involving the use of anthrax spores. Crown Copyright © 2013. Published by Elsevier B.V. All rights reserved.

  11. Computational simulation of biomolecules transport with multi-physics near microchannel surface for development of biomolecules-detection devices.

    Science.gov (United States)

    Suzuki, Yuma; Shimizu, Tetsuhide; Yang, Ming

    2017-01-01

    The quantitative evaluation of the biomolecules transport with multi-physics in nano/micro scale is demanded in order to optimize the design of microfluidics device for the biomolecules detection with high detection sensitivity and rapid diagnosis. This paper aimed to investigate the effectivity of the computational simulation using the numerical model of the biomolecules transport with multi-physics near a microchannel surface on the development of biomolecules-detection devices. The biomolecules transport with fluid drag force, electric double layer (EDL) force, and van der Waals force was modeled by Newtonian Equation of motion. The model validity was verified in the influence of ion strength and flow velocity on biomolecules distribution near the surface compared with experimental results of previous studies. The influence of acting forces on its distribution near the surface was investigated by the simulation. The trend of its distribution to ion strength and flow velocity was agreement with the experimental result by the combination of all acting forces. Furthermore, EDL force dominantly influenced its distribution near its surface compared with fluid drag force except for the case of high velocity and low ion strength. The knowledges from the simulation might be useful for the design of biomolecules-detection devices and the simulation can be expected to be applied on its development as the design tool for high detection sensitivity and rapid diagnosis in the future.

  12. CARIES DETECTION WITH LASER FLUORESCENCE DEVICES. LIMITATIONS OF THEIR USE

    Directory of Open Access Journals (Sweden)

    Andreas Spaveras

    2017-03-01

    Data synthesis: DD and DDPen are useful devices for caries detection on the occlusal tooth surfaces. Their main advantages are the very high reproducibility of measurements (>0.90, the ease of handling and the quantification and monitoring capacity. Their main limitations are the relatively low specificity for enamel lesions, the necessity of unstained surfaces and absence of plaque and pastes during measurements and the absence of a universal, clinically functional calibration value (COV. Conclusion: Further studies are required for more reliable data analysis and clinical interpretation of the relevant results.

  13. Detection and identification of Rift Valley fever virus in mosquito vectors by quantitative real-time PCR.

    Science.gov (United States)

    Mwaengo, D; Lorenzo, G; Iglesias, J; Warigia, M; Sang, R; Bishop, R P; Brun, A

    2012-10-01

    Diagnostic methods allowing for rapid identification of pathogens are crucial for controlling and preventing dissemination after disease outbreaks as well as for use in surveillance programs. For arboviruses, detection of the presence of virus in their arthropod hosts is important for monitoring of viral activity and quantitative information is useful for modeling of transmission dynamics. In this study, molecular detection of Rift Valley fever virus (RVFV) in mosquito samples from the 2006 to 2007 East African outbreaks was performed using quantitative real-time PCR assay (qRT-PCR). Specific RVFV sequence-based primer/fluorogenic (TaqMan) probe sets were derived from the L and S RNA segments of the virus. Both primer-probe L and S segment-based combinations detected genomic RVFV sequences, with generally comparable levels of sensitivity. Viral loads from three mosquito species, Aedes mcintoshi, Aedes ochraceus and Mansonia uniformis were estimated and significant differences of between 5- and 1000-fold were detected between Ae. mcintoshi and M. uniformis using both the L and S primer-probe-based assays. The genetic relationships of the viral sequences in mosquito samples were established by partial M segment sequencing and assigned to the two previously described viral lineages defined by analysis of livestock isolates obtained during the 2006-2007 outbreak, confirming that similar viruses were present in both the vector and mammalian host. The data confirms the utility of qRT-PCR for identification and initial quantification of virus in mosquito samples during RVFV outbreaks. Copyright © 2012 Elsevier B.V. All rights reserved.

  14. Radioisotope Identification Of Shielded And Masked SNM RDD Materials

    International Nuclear Information System (INIS)

    Salaymeh, S.; Jeffcoat, R.

    2010-01-01

    Sonar and speech techniques have been investigated to improve functionality and enable handheld and other man-portable, mobile, and portal systems to positively detect and identify illicit nuclear materials, with minimal data and with minimal false positives and false negatives. RadSonar isotope detection and identification is an algorithm development project funded by NA-22 and employing the resources of Savannah River National Laboratory and three University Laboratories (JHU-APL, UT-ARL, and UW-APL). Algorithms have been developed that improve the probability of detection and decrease the number of false positives and negatives. Two algorithms have been developed and tested. The first algorithm uses support vector machine (SVM) classifiers to determine the most prevalent nuclide(s) in a spectrum. It then uses a constrained weighted least squares fit to estimate and remove the contribution of these nuclide(s) to the spectrum, iterating classification and fitting until there is nothing of significance left. If any Special Nuclear Materials (SNMs) were detected in this process, a second tier of more stringent classifiers are used to make the final SNM alert decision. The second algorithm is looking at identifying existing feature sets that would be relevant in the radioisotope identification context. The underlying philosophy here is to identify parallels between the physics and/or the structures present in the data for the two applications (speech analysis and gamma spectroscopy). The expectation is that similar approaches may work in both cases. The mel-frequency cepstral representation of spectra is widely used in speech, particularly for two reasons: approximation of the response of the human ear, and simplicity of channel effect separation (in this context, a 'channel' is a method of signal transport that affects the signal, examples being vocal tract shape, room echoes, and microphone response). Measured and simulated gamma-ray spectra from a hand

  15. Detection Identification and Quantification of Keto-Hydroperoxides in Low-Temperature Oxidation.

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, Nils; Moshammer, Kai; Jasper, Ahren W.

    2017-07-01

    Keto-hydroperoxides are reactive partially oxidized intermediates that play a central role in chain-branching reactions during the low-temperature oxidation of hydrocarbons. In this Perspective, we outline how these short lived species can be detected, identified, and quantified using integrated experimental and theoretical approaches. The procedures are based on direct molecular-beam sampling from reactive environments, followed by mass spectrometry with single-photon ionization, identification of fragmentation patterns, and theoretical calculations of ionization thresholds, fragment appearance energies, and photoionization cross sections. Using the oxidation of neo-pentane and tetrahydrofuran as examples, the individual steps of the experimental approaches are described in depth together with a detailed description of the theoretical efforts. For neo-pentane, the experimental data are consistent with the calculated ionization and fragment appearance energies of the keto-hydroperoxide, thus adding confidence to the analysis routines and the employed levels of theory. For tetrahydrofuran, multiple keto-hydroperoxide isomers are possible due to the presence of nonequivalent O2 addition sites. Despite this additional complexity, the experimental data allow for the identification of two to four keto-hydroperoxides. Mole fraction profiles of the keto-hydroperoxides, which are quantified using calculated photoionization cross sections, are provided together with estimated uncertainties as function of the temperature of the reactive mixture and can serve as validation targets for chemically detailed mechanisms.

  16. Grazing incidence angle based sensing approach integrated with fiber-optic Fourier transform infrared (FO-FTIR) spectroscopy for remote and label-free detection of medical device contaminations

    Energy Technology Data Exchange (ETDEWEB)

    Hassan, Moinuddin, E-mail: moinuddin.hassan@fda.hhs.gov; Ilev, Ilko [Optical Therapeutics and Medical Nanophotonics Laboratory, Division of Biomedical Physics, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, U.S. Food and Drug Administration, Silver Spring, Maryland 20993 (United States)

    2014-10-15

    Contamination of medical devices has become a critical and prevalent public health safety concern since medical devices are being increasingly used in clinical practices for diagnostics, therapeutics and medical implants. The development of effective sensing methods for real-time detection of pathogenic contamination is needed to prevent and reduce the spread of infections to patients and the healthcare community. In this study, a hollow-core fiber-optic Fourier transform infrared spectroscopy methodology employing a grazing incidence angle based sensing approach (FO-FTIR-GIA) was developed for detection of various biochemical contaminants on medical device surfaces. We demonstrated the sensitivity of FO-FTIR-GIA sensing approach for non-contact and label-free detection of contaminants such as lipopolysaccharide from various surface materials relevant to medical device. The proposed sensing system can detect at a minimum loading concentration of approximately 0.7 μg/cm{sup 2}. The FO-FTIR-GIA has the potential for the detection of unwanted pathogen in real time.

  17. An efficient enzyme-powered micromotor device fabricated by cyclic alternate hybridization assembly for DNA detection.

    Science.gov (United States)

    Fu, Shizhe; Zhang, Xueqing; Xie, Yuzhe; Wu, Jie; Ju, Huangxian

    2017-07-06

    An efficient enzyme-powered micromotor device was fabricated by assembling multiple layers of catalase on the inner surface of a poly(3,4-ethylenedioxythiophene and sodium 4-styrenesulfonate)/Au microtube (PEDOT-PSS/Au). The catalase assembly was achieved by programmed DNA hybridization, which was performed by immobilizing a designed sandwich DNA structure as the sensing unit on the PEDOT-PSS/Au, and then alternately hybridizing with two assisting DNA to bind the enzyme for efficient motor motion. The micromotor device showed unique features of good reproducibility, stability and motion performance. Under optimal conditions, it showed a speed of 420 μm s -1 in 2% H 2 O 2 and even 51 μm s -1 in 0.25% H 2 O 2 . In the presence of target DNA, the sensing unit hybridized with target DNA to release the multi-layer DNA as well as the multi-catalase, resulting in a decrease of the motion speed. By using the speed as a signal, the micromotor device could detect DNA from 10 nM to 1 μM. The proposed micromotor device along with the cyclic alternate DNA hybridization assembly technique provided a new path to fabricate efficient and versatile micromotors, which would be an exceptional tool for rapid and simple detection of biomolecules.

  18. Crowdsourcing seizure detection: algorithm development and validation on human implanted device recordings.

    Science.gov (United States)

    Baldassano, Steven N; Brinkmann, Benjamin H; Ung, Hoameng; Blevins, Tyler; Conrad, Erin C; Leyde, Kent; Cook, Mark J; Khambhati, Ankit N; Wagenaar, Joost B; Worrell, Gregory A; Litt, Brian

    2017-06-01

    There exist significant clinical and basic research needs for accurate, automated seizure detection algorithms. These algorithms have translational potential in responsive neurostimulation devices and in automatic parsing of continuous intracranial electroencephalography data. An important barrier to developing accurate, validated algorithms for seizure detection is limited access to high-quality, expertly annotated seizure data from prolonged recordings. To overcome this, we hosted a kaggle.com competition to crowdsource the development of seizure detection algorithms using intracranial electroencephalography from canines and humans with epilepsy. The top three performing algorithms from the contest were then validated on out-of-sample patient data including standard clinical data and continuous ambulatory human data obtained over several years using the implantable NeuroVista seizure advisory system. Two hundred teams of data scientists from all over the world participated in the kaggle.com competition. The top performing teams submitted highly accurate algorithms with consistent performance in the out-of-sample validation study. The performance of these seizure detection algorithms, achieved using freely available code and data, sets a new reproducible benchmark for personalized seizure detection. We have also shared a 'plug and play' pipeline to allow other researchers to easily use these algorithms on their own datasets. The success of this competition demonstrates how sharing code and high quality data results in the creation of powerful translational tools with significant potential to impact patient care. © The Author (2017). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  19. An embedded point-of-care malaria screening device for low-resource regions (Conference Presentation)

    Science.gov (United States)

    Das, Sayantan; Mandal, Subhamoy; Das, Debnath; Malviya, Richa; Garud, Hrushikesh T.; Ray, Ajoy K.

    2016-03-01

    In this article we propose a point-of-care screening device for the detection and identification of malaria parasite, plasmodium vivax, plasmodium malaria, plasmodium oval and plasmodium falciparum with a time frame of 15-20 minute. In our device we can provide 97-98% sensitivity for each species as we are using traditional staining methods for detecting the parasites. In addition, as we are also quantifying the parasites, it is possible to provide an accurate estimate about the malarial stage of the patient. The image processing approach increases the total numbers of samples screened by reducing interventions of trained pathologists. This helps in reducing the delays in screening process arising from increased number of potential cases based on seasonal and local variations. The same reduces mortality rate by faster diagnosis and reduced false negative detections (i.e. increased sensitivity). The system can also be integrated with telemedicine platform to obtain inputs from medical practitioners at tertiary healthcare units for diagnostic decision making. Through this paper, we present the functional prototype of this device containing all the integrated parts. The prototype incorporates image acquisition, image processing, storage, multimedia transmission and reporting environment for a low cost PDA device. It is a portable device capable of scanning slides. The acquired image will be preprocessed and processed to get desired output. The device is capable of transmitting and storing pathological information to database placed in a distant pathological center for further consultation.

  20. Safety device of thermonuclear device

    International Nuclear Information System (INIS)

    Aoki, Isao; Ueda, Shuzo; Seki, Yasushi; Sakurai, Akiko; Kasahara, Fumio; Obara, Atsushi; Yamauchi, Michinori.

    1997-01-01

    The present invention provides a safety device against an event of intrusion of coolants in a vacuum vessel. Namely, a coolant supply system comprises cooling tubes for supplying coolants to main reactor structure components including a vacuum vessel. A detection means detects leakage of coolants in the vacuum vessel. A coolant supply control means controls the supply of coolants to the main reactor structural components based on the leakage detection signals of the detection means. A stagnated material discharging means discharges stagnated materials in the main reactor structural components caused by the leakage of coolants. The leakage of coolants (for example, water) in the vacuum vessel can thus be detected by the water detection device in the vacuum vessel. A control value of a coolant supply means is closed by the leakage detection signals. The supply of coolants to the main reactor structural components is restricted to suppress the leakage. The stagnated materials are discharged to a tank by way of a water draining valve. (I.S.)

  1. The detection of the coal roof interface by use of high pressure water

    Science.gov (United States)

    1981-01-01

    A device whereby water jets can be used to detect the interface between coal and the overlying roof rock is described. Once this identification is made this distance can be measured using instruments such as the autofocus systems recently developed in the photographic industry. Experiments carried out show that the device can discriminate between coal and rock at coal thicknesses up to 8 inches. An autofocus system was examined which indicates accuracies of better than 0.1 inches.

  2. 21 CFR 872.2050 - Dental sonography device.

    Science.gov (United States)

    2010-04-01

    ... § 872.9. (b) Dental sonography device for interpretation and diagnosis—(1) Identification. A dental sonography device for interpretation and diagnosis is an electrically powered device, intended to interpret temporomandibular joint sounds for the diagnosis of temporomandibular joint disorders and associated orofacial pain...

  3. 21 CFR 864.9750 - Heat-sealing device.

    Science.gov (United States)

    2010-04-01

    ... and Blood Products § 864.9750 Heat-sealing device. (a) Identification. A heat-sealing device is a device intended for medical purposes that uses heat to seal plastic bags containing blood or blood... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Heat-sealing device. 864.9750 Section 864.9750...

  4. Performance of handheld electrocardiogram devices to detect atrial fibrillation in a cardiology and geriatric ward setting.

    Science.gov (United States)

    Desteghe, Lien; Raymaekers, Zina; Lutin, Mark; Vijgen, Johan; Dilling-Boer, Dagmara; Koopman, Pieter; Schurmans, Joris; Vanduynhoven, Philippe; Dendale, Paul; Heidbuchel, Hein

    2017-01-01

    To determine the usability, accuracy, and cost-effectiveness of two handheld single-lead electrocardiogram (ECG) devices for atrial fibrillation (AF) screening in a hospital population with an increased risk for AF. Hospitalized patients (n = 445) at cardiological or geriatric wards were screened for AF by two handheld ECG devices (MyDiagnostick and AliveCor). The performance of the automated algorithm of each device was evaluated against a full 12-lead or 6-lead ECG recording. All ECGs and monitor tracings were also independently reviewed in a blinded fashion by two electrophysiologists. Time investments by nurses and physicians were tracked and used to estimate cost-effectiveness of different screening strategies. Handheld recordings were not possible in 7 and 21.4% of cardiology and geriatric patients, respectively, because they were not able to hold the devices properly. Even after the exclusion of patients with an implanted device, sensitivity and specificity of the automated algorithms were suboptimal (Cardiology: 81.8 and 94.2%, respectively, for MyDiagnostick; 54.5 and 97.5%, respectively, for AliveCor; Geriatrics: 89.5 and 95.7%, respectively, for MyDiagnostick; 78.9 and 97.9%, respectively, for AliveCor). A scenario based on automated AliveCor evaluation in patients without AF history and without an implanted device proved to be the most cost-effective method, with a provider cost to identify one new AF patient of €193 and €82 at cardiology and geriatrics, respectively. The cost to detect one preventable stroke per year would be €7535 and €1916, respectively (based on average CHA 2 DS 2 -VASc of 3.9 ± 2.0 and 5.0 ± 1.5, respectively). Manual interpretation increases sensitivity, but decreases specificity, doubling the cost per detected patient, but remains cheaper than sole 12-lead ECG screening. Using AliveCor or MyDiagnostick handheld recorders requires a structured screening strategy to be effective and cost-effective in a hospital setting

  5. Development and Validation of a Spike Detection and Classification Algorithm Aimed at Implementation on Hardware Devices

    Directory of Open Access Journals (Sweden)

    E. Biffi

    2010-01-01

    Full Text Available Neurons cultured in vitro on MicroElectrode Array (MEA devices connect to each other, forming a network. To study electrophysiological activity and long term plasticity effects, long period recording and spike sorter methods are needed. Therefore, on-line and real time analysis, optimization of memory use and data transmission rate improvement become necessary. We developed an algorithm for amplitude-threshold spikes detection, whose performances were verified with (a statistical analysis on both simulated and real signal and (b Big O Notation. Moreover, we developed a PCA-hierarchical classifier, evaluated on simulated and real signal. Finally we proposed a spike detection hardware design on FPGA, whose feasibility was verified in terms of CLBs number, memory occupation and temporal requirements; once realized, it will be able to execute on-line detection and real time waveform analysis, reducing data storage problems.

  6. Methods, microfluidic devices, and systems for detection of an active enzymatic agent

    Science.gov (United States)

    Sommer, Gregory J; Hatch, Anson V; Singh, Anup K; Wang, Ying-Chih

    2014-10-28

    Embodiments of the present invention provide methods, microfluidic devices, and systems for the detection of an active target agent in a fluid sample. A substrate molecule is used that contains a sequence which may cleave in the presence of an active target agent. A SNAP25 sequence is described, for example, that may be cleaved in the presence of Botulinum Neurotoxin. The substrate molecule includes a reporter moiety. The substrate molecule is exposed to the sample, and resulting reaction products separated using electrophoretic separation. The elution time of the reporter moiety may be utilized to identify the presence or absence of the active target agent.

  7. Multiplex PCR Assay for Identification of Six Different Staphylococcus spp. and Simultaneous Detection of Methicillin and Mupirocin Resistance

    OpenAIRE

    Campos-Peña, E.; Martín-Nuñez, E.; Pulido-Reyes, G.; Martín-Padrón, J.; Caro-Carrillo, E.; Donate-Correa, J.; Lorenzo-Castrillejo, I.; Alcoba-Flórez, J.; Machín, F.; Méndez-Alvarez, S.

    2014-01-01

    We describe a new, efficient, sensitive, and fast single-tube multiple-PCR protocol for the identification of the most clinically significant Staphylococcus spp. and the simultaneous detection of the methicillin and mupirocin resistance loci. The protocol identifies at the species level isolates belonging to S. aureus, S. epidermidis, S. haemolyticus, S. hominis, S. lugdunensis, and S. saprophyticus.

  8. Specific Detection and Identification of American Mulberry-Infecting and Italian Olive-Associated Strains of Xylella fastidiosa by Polymerase Chain Reaction.

    Science.gov (United States)

    Guan, Wei; Shao, Jonathan; Elbeaino, Toufic; Davis, Robert E; Zhao, Tingchang; Huang, Qi

    2015-01-01

    Xylella fastidiosa causes bacterial leaf scorch in many landscape trees including elm, oak, sycamore and mulberry, but methods for specific identification of a particular tree host species-limited strain or differentiation of tree-specific strains are lacking. It is also unknown whether a particular landscape tree-infecting X. fastidiosa strain is capable of infecting multiple landscape tree species in an urban environment. We developed two PCR primers specific for mulberry-infecting strains of X. fastidiosa based on the nucleotide sequence of a unique open reading frame identified only in mulberry-infecting strains among all the North and South American strains of X. fastidiosa sequenced to date. PCR using the primers allowed for detection and identification of mulberry-infecting X. fastidiosa strains in cultures and in samples collected from naturally infected mulberry trees. In addition, no mixed infections with or non-specific detections of the mulberry-infecting strains of X. fastidiosa were found in naturally X. fastidiosa-infected oak, elm and sycamore trees growing in the same region where naturally infected mulberry trees were grown. This genotype-specific PCR assay will be valuable for disease diagnosis, studies of strain-specific infections in insects and plant hosts, and management of diseases caused by X. fastidiosa. Unexpectedly but interestingly, the unique open reading frame conserved in the mulberry-infecting strains in the U. S. was also identified in the recently sequenced olive-associated strain CoDiRO isolated in Italy. When the primer set was tested against naturally infected olive plant samples collected in Italy, it allowed for detection of olive-associated strains of X. fastidiosa in Italy. This PCR assay, therefore, will also be useful for detection and identification of the Italian group of X. fastidiosa strains to aid understanding of the occurrence, evolution and biology of this new group of X. fastidiosa strains.

  9. Specific Detection and Identification of American Mulberry-Infecting and Italian Olive-Associated Strains of Xylella fastidiosa by Polymerase Chain Reaction.

    Directory of Open Access Journals (Sweden)

    Wei Guan

    Full Text Available Xylella fastidiosa causes bacterial leaf scorch in many landscape trees including elm, oak, sycamore and mulberry, but methods for specific identification of a particular tree host species-limited strain or differentiation of tree-specific strains are lacking. It is also unknown whether a particular landscape tree-infecting X. fastidiosa strain is capable of infecting multiple landscape tree species in an urban environment. We developed two PCR primers specific for mulberry-infecting strains of X. fastidiosa based on the nucleotide sequence of a unique open reading frame identified only in mulberry-infecting strains among all the North and South American strains of X. fastidiosa sequenced to date. PCR using the primers allowed for detection and identification of mulberry-infecting X. fastidiosa strains in cultures and in samples collected from naturally infected mulberry trees. In addition, no mixed infections with or non-specific detections of the mulberry-infecting strains of X. fastidiosa were found in naturally X. fastidiosa-infected oak, elm and sycamore trees growing in the same region where naturally infected mulberry trees were grown. This genotype-specific PCR assay will be valuable for disease diagnosis, studies of strain-specific infections in insects and plant hosts, and management of diseases caused by X. fastidiosa. Unexpectedly but interestingly, the unique open reading frame conserved in the mulberry-infecting strains in the U. S. was also identified in the recently sequenced olive-associated strain CoDiRO isolated in Italy. When the primer set was tested against naturally infected olive plant samples collected in Italy, it allowed for detection of olive-associated strains of X. fastidiosa in Italy. This PCR assay, therefore, will also be useful for detection and identification of the Italian group of X. fastidiosa strains to aid understanding of the occurrence, evolution and biology of this new group of X. fastidiosa strains.

  10. The combined rapid detection and species-level identification of yeasts in simulated blood culture using a colorimetric sensor array.

    Directory of Open Access Journals (Sweden)

    Nabin K Shrestha

    Full Text Available A colorimetric sensor array (CSA has been demonstrated to rapidly detect and identify bacteria growing in blood cultures by obtaining a species-specific "fingerprint" of the volatile organic compounds (VOCs produced during growth. This capability has been demonstrated in prokaryotes, but has not been reported for eukaryotic cells growing in culture. The purpose of this study was to explore if a disposable CSA could differentially identify 7 species of pathogenic yeasts growing in blood culture.Culture trials of whole blood inoculated with a panel of clinically important pathogenic yeasts at four different microorganism loads were performed. Cultures were done in both standard BacT/Alert and CSA-embedded bottles, after adding 10 mL of spiked blood to each bottle. Color changes in the CSA were captured as images by an optical scanner at defined time intervals. The captured images were analyzed to identify the yeast species. Time to detection by the CSA was compared to that in the BacT/Alert system.One hundred sixty-two yeast culture trials were performed, including strains of several species of Candida (Ca. albicans, Ca. glabrata, Ca. parapsilosis, and Ca. tropicalis, Clavispora (synonym Candida lusitaniae, Pichia kudriavzevii (synonym Candida krusei and Cryptococcus neoformans, at loads of 8.2 × 105, 8.3 × 103, 8.5 × 101, and 1.7 CFU/mL. In addition, 8 negative trials (no yeast were conducted. All negative trials were correctly identified as negative, and all positive trials were detected. Colorimetric responses were species-specific and did not vary by inoculum load over the 500000-fold range of loads tested, allowing for accurate species-level identification. The mean sensitivity for species-level identification by CSA was 74% at detection, and increased with time, reaching almost 95% at 4 hours after detection. At an inoculum load of 1.7 CFU/mL, mean time to detection with the CSA was 6.8 hours (17% less than with the BacT/Alert platform

  11. A method and device for reducing background in well logging devices using inelastic gamma rays

    International Nuclear Information System (INIS)

    Culver, R.B.

    1974-01-01

    The invention relates to a well logging device, of the type comprising a source of pulsed neutrons and means for detecting radioactivity. The device comprises means adapted to interrupt the neutron source emission in response to the detection of a single gamma radiation showing a pre-determined feature [fr

  12. Rapid detection and identification of pathogenic mycobacteria by combining radiometric and nucleic acid probe methods

    International Nuclear Information System (INIS)

    Ellner, P.D.; Kiehn, T.E.; Cammarata, R.; Hosmer, M.

    1988-01-01

    The combination of radiometric methodology (BACTEC 12B) and probe technology for recovery and identification of mycobacteria was studied in two large hospital laboratories. The sediment from vials with positive growth indices was tested with DNA probes specific for Mycobacterium tuberculosis, Mycobacterium avium, and Mycobacterium intracellulare. The sensitivity of the radiometric method and the specificity of the probes resulted in a marked reduction in the time to the final report. Biochemical testing could be eliminated on isolates giving a positive reaction with one of the probes. Some 176 isolates of M. tuberculosis, 110 of M. avium, and 5 of M. intracellulare were recovered. Two-thirds of these isolates were detected and identified within 2 weeks of inoculation and the remainder was detected by 4 weeks, a reduction of 5 to 7 weeks to the final report

  13. Root Exploit Detection and Features Optimization: Mobile Device and Blockchain Based Medical Data Management.

    Science.gov (United States)

    Firdaus, Ahmad; Anuar, Nor Badrul; Razak, Mohd Faizal Ab; Hashem, Ibrahim Abaker Targio; Bachok, Syafiq; Sangaiah, Arun Kumar

    2018-05-04

    The increasing demand for Android mobile devices and blockchain has motivated malware creators to develop mobile malware to compromise the blockchain. Although the blockchain is secure, attackers have managed to gain access into the blockchain as legal users, thereby comprising important and crucial information. Examples of mobile malware include root exploit, botnets, and Trojans and root exploit is one of the most dangerous malware. It compromises the operating system kernel in order to gain root privileges which are then used by attackers to bypass the security mechanisms, to gain complete control of the operating system, to install other possible types of malware to the devices, and finally, to steal victims' private keys linked to the blockchain. For the purpose of maximizing the security of the blockchain-based medical data management (BMDM), it is crucial to investigate the novel features and approaches contained in root exploit malware. This study proposes to use the bio-inspired method of practical swarm optimization (PSO) which automatically select the exclusive features that contain the novel android debug bridge (ADB). This study also adopts boosting (adaboost, realadaboost, logitboost, and multiboost) to enhance the machine learning prediction that detects unknown root exploit, and scrutinized three categories of features including (1) system command, (2) directory path and (3) code-based. The evaluation gathered from this study suggests a marked accuracy value of 93% with Logitboost in the simulation. Logitboost also helped to predicted all the root exploit samples in our developed system, the root exploit detection system (RODS).

  14. Detection of drugs of abuse in exhaled breath using a device for rapid collection: comparison with plasma, urine and self-reporting in 47 drug users.

    Science.gov (United States)

    Beck, Olof; Stephanson, Niclas; Sandqvist, Sören; Franck, Johan

    2013-06-01

    Exhaled breath has recently been identified as a matrix for the detection of drugs of abuse. This work aims to further document this application using a new and simple collection device in patients following recovery from acute intoxication. Breath, plasma and urine samples were collected from 47 patients (38 males, age range 25-74) together with interview data. Analysis of breath and plasma samples was done by liquid chromatography-mass spectrometry methods. Urine was screened using immunochemical reagents and positive findings confirmed with liquid chromatography-mass spectrometry methods. The 12 analytes investigated were: methadone, amphetamine, methamphetamine, 6-acetylmorphine, morphine, benzoylecgonine, cocaine, diazepam, oxazepam, alprazolam, buprenorphine and tetrahydrocannabinol. In all 47 cases, recent intake of an abused substance prior to admission was reported, but in one case the substance (ketobemidone) was not investigated. In 40 of the remaining cases (87%) breath analysis gave a positive finding of any of the substances that were part of the analytical investigation. Identifications were based on correct chromatographic retention time and product ion ratios obtained in selected reaction monitoring mode. In general, data from breath, plasma, urine and self-reporting were in good agreement, but in 23% of the cases substances were detected that had not been self-reported. All substances covered were detected in a number of breath samples. Considering that breath sampling was often done about 24 h after intake, the detection rate was considered to be high for most substances. Analytes with low detection rates were benzodiazepines, and a further increase in analytical sensitivity is needed to overcome this. This study further supports use of exhaled breath as a new matrix in clinical toxicology.

  15. Abnormal sound detection device

    International Nuclear Information System (INIS)

    Yamada, Izumi; Matsui, Yuji.

    1995-01-01

    Only components synchronized with rotation of pumps are sampled from detected acoustic sounds, to judge the presence or absence of abnormality based on the magnitude of the synchronized components. A synchronized component sampling means can remove resonance sounds and other acoustic sounds generated at a synchronously with the rotation based on the knowledge that generated acoustic components in a normal state are a sort of resonance sounds and are not precisely synchronized with the number of rotation. On the other hand, abnormal sounds of a rotating body are often caused by compulsory force accompanying the rotation as a generation source, and the abnormal sounds can be detected by extracting only the rotation-synchronized components. Since components of normal acoustic sounds generated at present are discriminated from the detected sounds, reduction of the abnormal sounds due to a signal processing can be avoided and, as a result, abnormal sound detection sensitivity can be improved. Further, since it is adapted to discriminate the occurrence of the abnormal sound from the actually detected sounds, the other frequency components which are forecast but not generated actually are not removed, so that it is further effective for the improvement of detection sensitivity. (N.H.)

  16. Trends in Biosensors for HPV: Identification and Diagnosis

    Directory of Open Access Journals (Sweden)

    Isaac A. M. Frías

    2015-01-01

    Full Text Available The conventional methodologies used for the detection of human papillomavirus (HPV present actually robust and reproducible advantages. However, at the same time, they involve complex protocols that sometimes are difficult to popularize. Over the first half of XX century, the adequate treatment of complex and delicate processes from a simple instrumental base seemed a fundamental and intrinsic contradiction. However, interdisciplinary trends have allowed the manipulation of tissues, proteins, and nucleic acids through innovative increasingly smaller devices. The proper diagnosis of HPV has seen great advances since biosensor researchers are employing its virus strains as models to study the interactions between the biorecognition element and the transducer. Additionally, all recent improvements and trends that material sciences, biotechnology, and data processing scientists excel for biosensors can be applied for the HPV detection platforms. In this review, we highlight the recent trends on materials, nanomaterials, and transducers for the specific detection and differentiation of HPV strains. The most influential methods for the detection and identification of these papillomaviruses include optical, electrochemical, and piezoelectric transducers; we will visit their sensibility and advantages. Additionally, we highlight the factors that contributed to the increasing importance of these biodevices as potential substitutes to conventional diagnostic methods.

  17. 3D Printed "Earable" Smart Devices for Real-Time Detection of Core Body Temperature.

    Science.gov (United States)

    Ota, Hiroki; Chao, Minghan; Gao, Yuji; Wu, Eric; Tai, Li-Chia; Chen, Kevin; Matsuoka, Yasutomo; Iwai, Kosuke; Fahad, Hossain M; Gao, Wei; Nyein, Hnin Yin Yin; Lin, Liwei; Javey, Ali

    2017-07-28

    Real-time detection of basic physiological parameters such as blood pressure and heart rate is an important target in wearable smart devices for healthcare. Among these, the core body temperature is one of the most important basic medical indicators of fever, insomnia, fatigue, metabolic functionality, and depression. However, traditional wearable temperature sensors are based upon the measurement of skin temperature, which can vary dramatically from the true core body temperature. Here, we demonstrate a three-dimensional (3D) printed wearable "earable" smart device that is designed to be worn on the ear to track core body temperature from the tympanic membrane (i.e., ear drum) based on an infrared sensor. The device is fully integrated with data processing circuits and a wireless module for standalone functionality. Using this smart earable device, we demonstrate that the core body temperature can be accurately monitored regardless of the environment and activity of the user. In addition, a microphone and actuator are also integrated so that the device can also function as a bone conduction hearing aid. Using 3D printing as the fabrication method enables the device to be customized for the wearer for more personalized healthcare. This smart device provides an important advance in realizing personalized health care by enabling real-time monitoring of one of the most important medical parameters, core body temperature, employed in preliminary medical screening tests.

  18. Neutron detection with integrated sub-2 nm Pt nanoparticles and 10B enriched dielectrics—A direct conversion device

    Directory of Open Access Journals (Sweden)

    Haisheng Zheng

    2016-07-01

    Full Text Available We report a direct conversion solid-state neutron detection device fabricated by combining the large neutron capture cross-section of 10B with the charge trapping attributes of sub-2 nm Pt nanoparticles (Pt NPs in MOSCAP structures. The 10B embedded polystyrene based neutron conversion layer also serves as the dielectric layer. Neutron sensing is achieved through carrier generation within the active 10B based dielectric layer and subsequent transfer to the embedded Pt NP layers, resulting in a significant change of the device's flat-band voltage upon ex-situ characterization. Both single and dual Pt NP layer embedded architectures, with varying electron addition energies, were tested within this study. While dual-layer Pt NPs embedded direct conversion devices with higher electron addition energy are shown to successfully capture charges generated through energetic reaction product upon neutron capture, the single Pt NP layer embedded device structure with lower electron addition energy displays signs of charge loss attributable to direct tunneling in the ex-situ capacitance–voltage measurement. Although only ex-situ detector operation is demonstrated within the realms of this study, sensitive in-situ neutron detectors and ultra-stable ex-situ dosimeters may be achievable utilizing a similar structure by fine-tuning the Pt NP size and the number of Pt NP layers in the device. Keywords: Neutron detection, Sub-2 nm Pt nanoparticles, 10B enriched dielectrics, Direct conversion, MOSCAP, Coulomb blockade

  19. Study of a charge-coupled device for high-energy-particle detection

    International Nuclear Information System (INIS)

    Bhuiya, A.H.

    1983-05-01

    This presentation is based on measurements made to evaluate the application of charge-coupled devices as detectors of high-energy particles. The experiment was performed with a Fairchild Linear 256-Cell CCD111 array (size 8μm x 17 μm/cell), utilizing a light source instead of a particle beam. It was observed that the minimum detectable signal was limited to approx. 488 electrons at -50 0 C, where the readout and exposure times were about 260 ms and 400 ms respectively. The transfer inefficiency of the CCD111 was determined to be approx. 10 -4 . It has been concluded that at a lower temperature (approx. -100 0 C) or with faster readout (approx. 10 ms), the CCD111 would be able to detect the total deposited energy of minimum-ionizing charged particles

  20. AC-conductance and capacitance measurements for ethanol vapor detection using carbon nanotube-polyvinyl alcohol composite based devices.

    Science.gov (United States)

    Greenshields, Márcia W C C; Meruvia, Michelle S; Hümmelgen, Ivo A; Coville, Neil J; Mhlanga, Sabelo D; Ceragioli, Helder J; Quispe, Jose C Rojas; Baranauskas, Vitor

    2011-03-01

    We report the preparation of inexpensive ethanol sensor devices using multiwalled carbon nanotube-polyvinyl alcohol composite films deposited onto interdigitated electrodes patterned on phenolite substrates. We investigate the frequency dependent response of the device conductance and capacitance showing that higher sensitivity is obtained at higher frequency if the conductance is used as sensing parameter. In the case of capacitance measurements, higher sensitivity is obtained at low frequency. Ethanol detection at a concentration of 300 ppm in air is demonstrated. More than 80% of the sensor conductance and capacitance variation response occurs in less than 20 s.

  1. Research on propane leak detection system and device based on mid infrared laser

    Science.gov (United States)

    Jiang, Meng; Wang, Xuefeng; Wang, Junlong; Wang, Yizhao; Li, Pan; Feng, Qiaoling

    2017-10-01

    Propane is a key component of liquefied petroleum gas (LPG) and crude oil volatile. This issue summarizes the recent progress of propane detection technology. Meanwhile, base on the development trend, our latest progress is also provided. We demonstrated a mid infrared propane sensor system, which is based on wavelength modulation spectroscopy (WMS) technique with a CW interband cascade laser (ICL) emitting at 3370.4nm. The ICL laser scanned over a sharp feature in the broader spectrum of propane, and harmonic signals are obtained by lock-in amplifier for gas concentration deduction. The surrounding gas is extracted into the fine optical absorption cell through the pump to realize online detection. The absorption cell is designed in mid infrared windows range. An example experimental setup is shown. The second harmonic signals 2f and first harmonic signals1f are obtained. We present the sensor performance test data including dynamic precision and temperature stability. The propane detection sensor system and device is portable can carried on the mobile inspection vehicle platforms or intelligent robot inspection platform to realize the leakage monitoring of whole oil gas tank area.

  2. Spill-Detector-and-Shutoff Device

    Science.gov (United States)

    Jarvis, M. R.; Fulton, D. S.

    1985-01-01

    Overflow in liquid chromatography systems rapidly detected and stopped. Spill-detector-and-shutoff device incorporated into liquid-chromatography system. When liquid from output nozzle spills on liquid sensor, device automatically shuts off pump and releases solenoid to pinch off flow in tube. Device uses common type of alarm circuit reset manually before normal operation resumes.

  3. A multiplex nested PCR for the detection and identification of Candida species in blood samples of critically ill paediatric patients.

    Science.gov (United States)

    Taira, Cleison Ledesma; Okay, Thelma Suely; Delgado, Artur Figueiredo; Ceccon, Maria Esther Jurfest Rivero; de Almeida, Margarete Teresa Gottardo; Del Negro, Gilda Maria Barbaro

    2014-07-21

    Nosocomial candidaemia is associated with high mortality rates in critically ill paediatric patients; thus, the early detection and identification of the infectious agent is crucial for successful medical intervention. The PCR-based techniques have significantly increased the detection of Candida species in bloodstream infections. In this study, a multiplex nested PCR approach was developed for candidaemia detection in neonatal and paediatric intensive care patients. DNA samples from the blood of 54 neonates and children hospitalised in intensive care units with suspected candidaemia were evaluated by multiplex nested PCR with specific primers designed to identify seven Candida species, and the results were compared with those obtained from blood cultures. The multiplex nested PCR had a detection limit of four Candida genomes/mL of blood for all Candida species. Blood cultures were positive in 14.8% of patients, whereas the multiplex nested PCR was positive in 24.0% of patients, including all culture-positive patients. The results obtained with the molecular technique were available within 24 hours, and the assay was able to identify Candida species with 100% of concordance with blood cultures. Additionally, the multiplex nested PCR detected dual candidaemia in three patients. Our proposed PCR method may represent an effective tool for the detection and identification of Candida species in the context of candidaemia diagnosis in children, showing highly sensitive detection and the ability to identify the major species involved in this infection.

  4. Fuel failure detection device

    International Nuclear Information System (INIS)

    Katagiri, Masaki.

    1979-01-01

    Purpose: To improve the SN ratio in the detection. Constitution: Improved precipitator method is provided. Scintillation detectors of a same function are provided respectively by each one before and after a gas reservoir for depositing fission products in the cover gas to detecting wires. The outputs from the two detectors (output from the wire not deposited with the fission products and the output from the wire after deposition) are compared to eliminate background noises resulted from not-decayed nucleides. A subtraction circuit is provided for the elimination. Since the background noises of the detecting wire can thus be measured and corrected on every detection, the SN ratio can be increased. (Ikeda, J.)

  5. High-Speed Device-Independent Quantum Random Number Generation without a Detection Loophole

    Science.gov (United States)

    Liu, Yang; Yuan, Xiao; Li, Ming-Han; Zhang, Weijun; Zhao, Qi; Zhong, Jiaqiang; Cao, Yuan; Li, Yu-Huai; Chen, Luo-Kan; Li, Hao; Peng, Tianyi; Chen, Yu-Ao; Peng, Cheng-Zhi; Shi, Sheng-Cai; Wang, Zhen; You, Lixing; Ma, Xiongfeng; Fan, Jingyun; Zhang, Qiang; Pan, Jian-Wei

    2018-01-01

    Quantum mechanics provides the means of generating genuine randomness that is impossible with deterministic classical processes. Remarkably, the unpredictability of randomness can be certified in a manner that is independent of implementation devices. Here, we present an experimental study of device-independent quantum random number generation based on a detection-loophole-free Bell test with entangled photons. In the randomness analysis, without the independent identical distribution assumption, we consider the worst case scenario that the adversary launches the most powerful attacks against the quantum adversary. After considering statistical fluctuations and applying an 80 Gb ×45.6 Mb Toeplitz matrix hashing, we achieve a final random bit rate of 114 bits /s , with a failure probability less than 10-5. This marks a critical step towards realistic applications in cryptography and fundamental physics tests.

  6. Versatile microfluidic total internal reflection (TIR)-based devices: application to microbeads velocity measurement and single molecule detection with upright and inverted microscope.

    Science.gov (United States)

    Le, Nam Cao Hoai; Yokokawa, Ryuji; Dao, Dzung Viet; Nguyen, Thien Duy; Wells, John C; Sugiyama, Susumu

    2009-01-21

    A poly(dimethylsiloxane) (PDMS) chip for Total Internal Reflection (TIR)-based imaging and detection has been developed using Si bulk micromachining and PDMS casting. In this paper, we report the applications of the chip on both inverted and upright fluorescent microscopes and confirm that two types of sample delivery platforms, PDMS microchannel and glass microchannel, can be easily integrated depending on the magnification of an objective lens needed to visualize a sample. Although any device configuration can be achievable, here we performed two experiments to demonstrate the versatility of the microfluidic TIR-based devices. The first experiment was velocity measurement of Nile red microbeads with nominal diameter of 500 nm in a pressure-driven flow. The time-sequenced fluorescent images of microbeads, illuminated by an evanescent field, were cross-correlated by a Particle Image Velocimetry (PIV) program to obtain near-wall velocity field of the microbeads at various flow rates from 500 nl/min to 3000 nl/min. We then evaluated the capabilities of the device for Single Molecule Detection (SMD) of fluorescently labeled DNA molecules from 30 bp to 48.5 kbp and confirm that DNA molecules as short as 1105 bp were detectable. Our versatile, integrated device could provide low-cost and fast accessibility to Total Internal Reflection Fluorescent Microscopy (TIRFM) on both conventional upright and inverted microscopes. It could also be a useful component in a Micro-Total Analysis System (micro-TAS) to analyze nanoparticles or biomolecules near-wall transport or motion.

  7. Experimental model of the device for detection of nuclear cycle materials by photoneutron technology

    International Nuclear Information System (INIS)

    Bakalyarov, A.M.; Karetnikov, M.D.; Kozlov, K.N.; Lebedev, V.I.; Meleshko, E.A.; Obinyakov, B.A.; Ostashev, I.E.; Tupikin, N.A.; Yakovlev, G.V.

    2007-01-01

    The inherent complexity of sea container control makes them potentially dangerous for smuggling nuclear materials. The experts believe that only active technologies based on recording the products of induced radiation from sensitive materials might solve the problem. The paper reports on the experimental model of the device on the basis of the electron LINAC U-28 for detection of nuclear materials by photonuclear technology. The preliminary numerical optimization of output units (converter, filter, collimator) for shaping the bremsstrahlung was carried out. The setup of experimental device and initial results of recording the prompt and delayed fission products are discussed

  8. In-plane object detection : detection algorithms and visibility problems

    NARCIS (Netherlands)

    Jovanovic, N.

    2011-01-01

    A large number of devices today incorporate some form of detection of objects and people in a given environment. Various detection technologies have been developed over the years, as a response to many different demands. The devices such as video surveillance systems, scanners, touch screens and

  9. 21 CFR 880.6300 - Implantable radiofrequency transponder system for patient identification and health information.

    Science.gov (United States)

    2010-04-01

    ... patient identification and health information. 880.6300 Section 880.6300 Food and Drugs FOOD AND DRUG... radiofrequency transponder system for patient identification and health information. (a) Identification. An implantable radiofrequency transponder system for patient identification and health information is a device...

  10. Detection and identification of extra virgin olive oil adulteration by GC-MS combined with chemometrics.

    Science.gov (United States)

    Yang, Yang; Ferro, Miguel Duarte; Cavaco, Isabel; Liang, Yizeng

    2013-04-17

    In this study, an analytical method for the detection and identification of extra virgin olive oil adulteration with four types of oils (corn, peanut, rapeseed, and sunflower oils) was proposed. The variables under evaluation included 22 fatty acids and 6 other significant parameters (the ratio of linoleic/linolenic acid, oleic/linoleic acid, total saturated fatty acids (SFAs), polyunsaturated fatty acids (PUFAs), monounsaturated fatty acids (MUFAs), MUFAs/PUFAs). Univariate analyses followed by multivariate analyses were applied to the adulteration investigation. As a result, the univariate analyses demonstrated that higher contents of eicosanoic acid, docosanoic acid, tetracosanoic acid, and SFAs were the peculiarities of peanut adulteration and higher levels of linolenic acid, 11-eicosenoic acid, erucic acid, and nervonic acid the characteristics of rapeseed adulteration. Then, PLS-LDA made the detection of adulteration effective with a 1% detection limit and 90% prediction ability; a Monte Carlo tree identified the type of adulteration with 85% prediction ability.

  11. Apparatus for testing semiconductor devices and capacitors

    International Nuclear Information System (INIS)

    York, R.A.

    1984-01-01

    An apparatus is provided for testing semiconductor devices. The apparatus tests the impedance of the semiconductor devices in both conducting and non-conducting states to detect semiconductors whose impedance in the conducting state is too high or whose impedance in the non-conducting state is too low. The apparatus uses a battery source for low voltage d.c. The circuitry for detecting when the impedance is too high in the conducting state includes a lamp in series with the battery source and the semiconductor device, whereby the impedance of the semiconductor device determines whether sufficient current will flow through the lamp to cause the lamp to illuminate. A d.c. to d.c. converter is provided to boost the voltage from the battery source to a relatively high voltage d.c. The relatively high voltage d.c. can be connected by a switch to circuitry for detecting when the impedance of the semiconductor device in the non-conducting state is too low. The circuitry for detecting when the impedance of the semiconductor device is too low includes a resistor which senses the current flowing in the device and converts the current into a voltage proportional to the leakage current. This voltage is then compared against a fixed reference. Further circuitry is provided for providing a visual indication when the voltage representative of leakage in relation to the reference signal indicates that there is excessive current flow through the semiconductor device

  12. Multimodal Person Re-identification Using RGB-D Sensors and a Transient Identification Database

    DEFF Research Database (Denmark)

    Møgelmose, Andreas; Moeslund, Thomas B.; Nasrollahi, Kamal

    2013-01-01

    This paper describes a system for person re-identification using RGB-D sensors. The system covers the full flow, from detection of subjects, over contour extraction, to re-identification using soft biometrics. The biometrics in question are part-based color histograms and the subjects height...

  13. Detection of bacteria in suspension using a superconducting Quantum interference device

    Energy Technology Data Exchange (ETDEWEB)

    Grossman, H.L.; Myers, W.R.; Vreeland, V.J.; Alper, J.D.; Bertozzi, C.R.; Clarke, J.

    2003-06-09

    We demonstrate a technique for detecting magnetically-labeled Listeria monocytogenes and for measuring the binding rate between antibody-linked magnetic particles and bacteria. This assay, which is both sensitive and straightforward to perform, can quantify specific bacteria in a sample without the need to immobilize the bacteria or wash away unbound magnetic particles. In the measurement, we add 50 nm diameter superparamagnetic particles, coated with antibodies, to a liquid sample containing L. monocytogenes. We apply a pulsed magnetic field to align the magnetic dipole moments and use a high transition temperature Superconducting Quantum Interference Device (SQUID), an extremely sensitive detector of magnetic flux, to measure the magnetic relaxation signal when the field is turned off. Unbound particles randomize direction by Brownian rotation too quickly to be detected. In contrast, particles bound to L. monocytogenes are effectively immobilized and relax in about 1 s by rotation of the internal dipole moment. This Neel relaxation process is detected by the SQUID. The measurements indicate a detection limit of (5.6 {+-} 1.1) x 10{sup 6} L. monocytogenes for a 20 {micro}L sample volume. If the sample volume were reduced to 1 nL, we estimate that the detection limit could be improved to 230 {+-} 40 L. monocytogenes cells. Time-resolved measurements yield the binding rate between the particles and bacteria.

  14. Detection of bacteria in suspension using a superconducting Quantum interference device

    International Nuclear Information System (INIS)

    Grossman, H.L.; Myers, W.R.; Vreeland, V.J.; Alper, J.D.; Bertozzi, C.R.; Clarke, J.

    2003-01-01

    We demonstrate a technique for detecting magnetically-labeled Listeria monocytogenes and for measuring the binding rate between antibody-linked magnetic particles and bacteria. This assay, which is both sensitive and straightforward to perform, can quantify specific bacteria in a sample without the need to immobilize the bacteria or wash away unbound magnetic particles. In the measurement, we add 50 nm diameter superparamagnetic particles, coated with antibodies, to a liquid sample containing L. monocytogenes. We apply a pulsed magnetic field to align the magnetic dipole moments and use a high transition temperature Superconducting Quantum Interference Device (SQUID), an extremely sensitive detector of magnetic flux, to measure the magnetic relaxation signal when the field is turned off. Unbound particles randomize direction by Brownian rotation too quickly to be detected. In contrast, particles bound to L. monocytogenes are effectively immobilized and relax in about 1 s by rotation of the internal dipole moment. This Neel relaxation process is detected by the SQUID. The measurements indicate a detection limit of (5.6 ± 1.1) x 10 6 L. monocytogenes for a 20 (micro)L sample volume. If the sample volume were reduced to 1 nL, we estimate that the detection limit could be improved to 230 ± 40 L. monocytogenes cells. Time-resolved measurements yield the binding rate between the particles and bacteria

  15. Instant detection and identification of concealed explosive-related compounds: Induced Stokes Raman versus infrared.

    Science.gov (United States)

    Elbasuney, Sherif; El-Sherif, Ashraf F

    2017-01-01

    The instant detection of explosives and explosive-related compounds has become an urgent priority in recent years for homeland security and counter-terrorism applications. Modern techniques should offer enhancement in selectivity, sensitivity, and standoff distances. Miniaturisation, portability, and field-ruggedisation are crucial requirements. This study reports on instant and standoff identification of concealed explosive-related compounds using customized Raman technique. Stokes Raman spectra of common explosive-related compounds were generated and spectrally resolved to create characteristic finger print spectra. The scattered Raman emissions over the band 400:2000cm -1 were compared to infrared absorption using FTIR. It has been demonstrated that the two vibrational spectroscopic techniques were opposite and completing each other. Molecular vibrations with strong absorption in infrared (those involve strong change in dipole moments) induced weak signals in Raman and vice versa. The tailored Raman offered instant detection, high sensitivity, and standoff detection capabilities. Raman demonstrated characteristic fingerprint spectra with stable baseline and sharp intense peaks. Complete correlations of absorption/scattered signals to certain molecular vibrations were conducted to generate an entire spectroscopic profile of explosive-related compounds. This manuscript shades the light on Raman as one of the prevailing technologies for instantaneous detection of explosive-related compounds. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  16. OPTICAL correlation identification technology applied in underwater laser imaging target identification

    Science.gov (United States)

    Yao, Guang-tao; Zhang, Xiao-hui; Ge, Wei-long

    2012-01-01

    The underwater laser imaging detection is an effective method of detecting short distance target underwater as an important complement of sonar detection. With the development of underwater laser imaging technology and underwater vehicle technology, the underwater automatic target identification has gotten more and more attention, and is a research difficulty in the area of underwater optical imaging information processing. Today, underwater automatic target identification based on optical imaging is usually realized with the method of digital circuit software programming. The algorithm realization and control of this method is very flexible. However, the optical imaging information is 2D image even 3D image, the amount of imaging processing information is abundant, so the electronic hardware with pure digital algorithm will need long identification time and is hard to meet the demands of real-time identification. If adopt computer parallel processing, the identification speed can be improved, but it will increase complexity, size and power consumption. This paper attempts to apply optical correlation identification technology to realize underwater automatic target identification. The optics correlation identification technology utilizes the Fourier transform characteristic of Fourier lens which can accomplish Fourier transform of image information in the level of nanosecond, and optical space interconnection calculation has the features of parallel, high speed, large capacity and high resolution, combines the flexibility of calculation and control of digital circuit method to realize optoelectronic hybrid identification mode. We reduce theoretical formulation of correlation identification and analyze the principle of optical correlation identification, and write MATLAB simulation program. We adopt single frame image obtained in underwater range gating laser imaging to identify, and through identifying and locating the different positions of target, we can improve

  17. Generic detection and identification of pospiviroids.

    Science.gov (United States)

    Olivier, Thibaut; Demonty, Elisabeth; Fauche, Frédéric; Steyer, Stéphan

    2014-08-01

    A multiplex one-step RT-PCR aiming at detecting all pospiviroids known to be harmful to cultivated plants has been developed. Specificity, sensitivity, selectivity, repeatability and reproducibility of this test have been assessed in order to fulfill the recommendations of the EPPO standard PM7/98 and provide routine detection laboratories with a cost-effective, easy-to-use and robust pospiviroid detection test. To further understand the epidemiology and ease the management of pospiviroid outbreaks, this RT-PCR diagnostic test can be followed by direct sequencing of the amplicons to identify and characterize the detected pospiviroid isolates.

  18. Fast detection of genetic information by an optimized PCR in an interchangeable chip.

    KAUST Repository

    Wu, Jinbo

    2012-02-01

    In this paper, we report the construction of a polymerase chain reaction (PCR) device for fast amplification and detection of DNA. This device consists of an interchangeable PCR chamber, a temperature control component as well as an optical detection system. The DNA amplification happens on an interchangeable chip with the volumes as low as 1.25 μl, while the heating and cooling rate was as fast as 12.7°C/second ensuring that the total time needed of only 25 min to complete the 35 cycle PCR amplification. An optimized PCR with two-temperature approach for denaturing and annealing (Td and Ta) of DNA was also formulated with the PCR chip, with which the amplification of male-specific sex determining region Y (SRY) gene marker by utilizing raw saliva was successfully achieved and the genetic identification was in-situ detected right after PCR by the optical detection system.

  19. Incipient Fault Detection and Isolation of Field Devices in Nuclear Power Systems Using Principal Component Analysis

    International Nuclear Information System (INIS)

    Kaistha, Nitin; Upadhyaya, Belle R.

    2001-01-01

    An integrated method for the detection and isolation of incipient faults in common field devices, such as sensors and actuators, using plant operational data is presented. The approach is based on the premise that data for normal operation lie on a surface and abnormal situations lead to deviations from the surface in a particular way. Statistically significant deviations from the surface result in the detection of faults, and the characteristic directions of deviations are used for isolation of one or more faults from the set of typical faults. Principal component analysis (PCA), a multivariate data-driven technique, is used to capture the relationships in the data and fit a hyperplane to the data. The fault direction for each of the scenarios is obtained using the singular value decomposition on the state and control function prediction errors, and fault isolation is then accomplished from projections on the fault directions. This approach is demonstrated for a simulated pressurized water reactor steam generator system and for a laboratory process control system under single device fault conditions. Enhanced fault isolation capability is also illustrated by incorporating realistic nonlinear terms in the PCA data matrix

  20. Electronic security device

    Science.gov (United States)

    Eschbach, Eugene A.; LeBlanc, Edward J.; Griffin, Jeffrey W.

    1992-01-01

    The present invention relates to a security device having a control box (12) containing an electronic system (50) and a communications loop (14) over which the system transmits a signal. The device is constructed so that the communications loop can extend from the control box across the boundary of a portal such as a door into a sealed enclosure into which access is restricted whereby the loop must be damaged or moved in order for an entry to be made into the enclosure. The device is adapted for detecting unauthorized entries into such enclosures such as rooms or containers and for recording the time at which such entries occur for later reference. Additionally, the device detects attempts to tamper or interfere with the operation of the device itself and records the time at which such events take place. In the preferred embodiment, the security device includes a microprocessor-based electronic system (50) and a detection module (72) capable of registering changes in the voltage and phase of the signal transmitted over the loop.

  1. Electronic security device

    International Nuclear Information System (INIS)

    Eschbach, E.A.; LeBlanc, E.J.; Griffin, J.W.

    1992-01-01

    The present invention relates to a security device having a control box containing an electronic system and a communications loop over which the system transmits a signal. The device is constructed so that the communications loop can extend from the control box across the boundary of a portal such as a door into a sealed enclosure into which access is restricted whereby the loop must be damaged or moved in order for an entry to be made into the enclosure. The device is adapted for detecting unauthorized entries into such enclosures such as rooms or containers and for recording the time at which such entries occur for later reference. Additionally, the device detects attempts to tamper or interfere with the operation of the device itself and records the time at which such events take place. In the preferred embodiment, the security device includes a microprocessor-based electronic system and a detection module capable of registering changes in the voltage and phase of the signal transmitted over the loop. 11 figs

  2. Continuous-Flow Detector for Rapid Pathogen Identification

    Energy Technology Data Exchange (ETDEWEB)

    Barrett, Louise M. [Sandia National Lab. (SNL-CA), Livermore, CA (United States). Microfluidics; Skulan, Andrew J. [Sandia National Lab. (SNL-CA), Livermore, CA (United States). Microfluidics; Singh, Anup K. [Sandia National Lab. (SNL-CA), Livermore, CA (United States). Microfluidics; Cummings, Eric B. [Sandia National Lab. (SNL-CA), Livermore, CA (United States). Microfluidics; Fiechtner, Gregory J. [Sandia National Lab. (SNL-CA), Livermore, CA (United States). Microfluidics

    2006-09-01

    This report describes the continued development of a low-power, portable detector for the rapid identification of pathogens such as B. anthracis and smallpox. Based on our successful demonstration of the continuous filter/concentrator inlet, we believe strongly that the inlet section will enable differentiation between viable and non-viable populations, between types of cells, and between pathogens and background contamination. Selective, continuous focusing of particles in a microstream enables highly selective and sensitive identification using fluorescently labeled antibodies and other receptors such as peptides, aptamers, or small ligands to minimize false positives. Processes such as mixing and lysing will also benefit from the highly localized particle streams. The concentrator is based on faceted prisms to contract microfluidic flows while maintaining uniform flowfields. The resulting interfaces, capable of high throughput, serve as high-, low-, and band-pass filters to direct selected bioparticles to a rapid, affinity-based detection system. The proposed device is superior to existing array-based detectors as antibody-pathogen binding can be accomplished in seconds rather than tens of minutes or even hours. The system is being designed to interface with aerosol collectors under development by the National Laboratories or commercial systems. The focused stream is designed to be interrogated using diode lasers to differentiate pathogens by light scattering. Identification of particles is done using fluorescently labeled antibodies to tag the particles, followed by multiplexed laser-induced fluorescence (LIF) detection (achieved by labeling each antibody with a different dye).

  3. System theory in medical diagnostic devices: an overview.

    Science.gov (United States)

    Baura, Gail D

    2006-01-01

    Medical diagnostics refers to testing conducted either in vitro or in vivo to provide critical health care information for risk assessment, early diagnosis, treatment, or disease management. Typical in vivo diagnostic tests include the computed tomography scan, magnetic resonance imaging, and blood pressure screening. Typical in vitro diagnostic tests include cholesterol, Papanicolaou smear, and conventional glucose monitoring tests. Historically, devices associated with both types of diagnostics have used heuristic curve fitting during signal analysis. However, since the early 1990s, a few enterprising engineers and physicians have used system theory to improve their core processing for feature detection and system identification. Current applications include automated Pap smear screening for detection of cervical cancer and diagnosis of Alzheimer's disease. Future applications, such as disease prediction before symptom onset and drug treatment customization, have been catalyzed by the Human Genome Project.

  4. Automatic Defect Detection of Fasteners on the Catenary Support Device Using Deep Convolutional Neural Network

    NARCIS (Netherlands)

    Chen, Junwen; Liu, Zhigang; Wang, H.; Nunez Vicencio, Alfredo; Han, Zhiwei

    2018-01-01

    The excitation and vibration triggered by the long-term operation of railway vehicles inevitably result in defective states of catenary support devices. With the massive construction of high-speed electrified railways, automatic defect detection of diverse and plentiful fasteners on the catenary

  5. Exploring the capability of wireless near infrared spectroscopy as a portable seizure detection device for epilepsy patients.

    Science.gov (United States)

    Jeppesen, Jesper; Beniczky, Sándor; Johansen, Peter; Sidenius, Per; Fuglsang-Frederiksen, Anders

    2015-03-01

    Near infrared spectroscopy (NIRS) has proved useful in measuring significant hemodynamic changes in the brain during epileptic seizures. The advance of NIRS-technology into wireless and portable devices raises the possibility of using the NIRS-technology for portable seizure detection. This study used NIRS to measure changes in oxygenated (HbO), deoxygenated (HbR), and total hemoglobin (HbT) at left and right side of the frontal lobe in 33 patients with epilepsy undergoing long-term video-EEG monitoring. Fifteen patients had 34 focal seizures (20 temporal-, 11 frontal-, 2 parietal-lobe, one unspecific) recorded and analyzed with NIRS. Twelve parameters consisting of maximum increase and decrease changes of HbO, HbR and HbT during seizures (1 min before- to 3 min after seizure-onset) for left and right side, were compared with the patients' own non-seizure periods (a 2-h period and a 30-min exercise-period). In both non-seizure periods 4 min moving windows with maximum overlapping were applied to find non-seizure maxima of the 12 parameters. Detection was defined as positive when seizure maximum change exceeded non-seizure maximum change. When analyzing the 12 parameters separately the positive seizure detection was in the range of 6-24%. The increase in hemodynamics was in general better at detecting seizures (15-24%) than the decrease in hemodynamics (6-18%) (P=0.02). NIRS did not seem to be a suitable technology for generic seizure detection given the device, settings, and methods used in this study. There are still several challenges to overcome before the NIRS-technology can be used as a home-monitoring seizure detection device. Copyright © 2015 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.

  6. Simultaneous pre-concentration and separation on simple paper-based analytical device for protein analysis.

    Science.gov (United States)

    Niu, Ji-Cheng; Zhou, Ting; Niu, Li-Li; Xie, Zhen-Sheng; Fang, Fang; Yang, Fu-Quan; Wu, Zhi-Yong

    2018-02-01

    In this work, fast isoelectric focusing (IEF) was successfully implemented on an open paper fluidic channel for simultaneous concentration and separation of proteins from complex matrix. With this simple device, IEF can be finished in 10 min with a resolution of 0.03 pH units and concentration factor of 10, as estimated by color model proteins by smartphone-based colorimetric detection. Fast detection of albumin from human serum and glycated hemoglobin (HBA1c) from blood cell was demonstrated. In addition, off-line identification of the model proteins from the IEF fractions with matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) was also shown. This PAD IEF is potentially useful either for point of care test (POCT) or biomarker analysis as a cost-effective sample pretreatment method.

  7. Modeling of detective quantum efficiency considering scatter-reduction devices

    Energy Technology Data Exchange (ETDEWEB)

    Park, Ji Woong; Kim, Dong Woon; Kim, Ho Kyung [Pusan National University, Busan (Korea, Republic of)

    2016-05-15

    The reduction of signal-to-noise ratio (SNR) cannot be restored and thus has become a severe issue in digital mammography.1 Therefore, antiscatter grids are typically used in mammography. Scatter-cleanup performance of various scatter-reduction devices, such as air gaps,2 linear (1D) or cellular (2D) grids,3, 4 and slot-scanning devices,5 has been extensively investigated by many research groups. In the present time, a digital mammography system with the slotscanning geometry is also commercially available.6 In this study, we theoretically investigate the effect of scattered photons on the detective quantum efficiency (DQE) performance of digital mammography detectors by using the cascaded-systems analysis (CSA) approach. We show a simple DQE formalism describing digital mammography detector systems equipped with scatter reduction devices by regarding the scattered photons as additive noise sources. The LFD increased with increasing PMMA thickness, and the amounts of LFD indicated the corresponding SF. The estimated SFs were 0.13, 0.21, and 0.29 for PMMA thicknesses of 10, 20, and 30 mm, respectively. While the solid line describing the measured MTF for PMMA with 0 mm was the result of least-squares of regression fit using Eq. (14), the other lines were simply resulted from the multiplication of the fit result (for PMMA with 0 mm) with the (1-SF) estimated from the LFDs in the measured MTFs. Spectral noise-power densities over the entire frequency range were not much changed with increasing scatter. On the other hand, the calculation results showed that the spectral noise-power densities increased with increasing scatter. This discrepancy may be explained by that the model developed in this study does not account for the changes in x-ray interaction parameters for varying spectral shapes due to beam hardening with increasing PMMA thicknesses.

  8. Aspartate Aminotransferase and Alanine Aminotransferase Detection on Paper-Based Analytical Devices with Inkjet Printer-Sprayed Reagents

    Directory of Open Access Journals (Sweden)

    Hsiang-Li Wang

    2016-01-01

    Full Text Available General biochemistry detection on paper-based microanalytical devices (PADs uses pipette titration. However, such an approach is extremely time-consuming for large-scale detection processes. Furthermore, while automated methods are available for increasing the efficiency of large-scale PAD production, the related equipment is very expensive. Accordingly, this study proposes a low-cost method for PAD manufacture, in which the reagent is applied using a modified inkjet printer. The optimal reaction times for the detection of aspartate aminotransferase (AST and alanine aminotransferase (ALT are shown to be 6 and 7 min, respectively, given AST and ALT concentrations in the range of 5.4 to 91.2 U/L (R2 = 0.9932 and 5.38 to 86.1 U/L (R2 = 0.9944. The experimental results obtained using the proposed PADs for the concentration detection of AST and ALT in real human blood serum samples are found to be in good agreement with those obtained using a traditional spectrophotometric detection method by National Cheng Kung University hospital.

  9. Detection and identification of Toscana and other phleboviruses by RT-nested-PCR assays with degenerated primers.

    Science.gov (United States)

    Sánchez-Seco, María-Paz; Echevarría, José-Manuel; Hernández, Lourdes; Estévez, Domingo; Navarro-Marí, José-María; Tenorio, Antonio

    2003-09-01

    Phleboviruses are a large and widespread group of viruses that are transmitted by arthropods. Toscana virus is one of the principal agents that causes meningitis in humans during the summer in Italy and, possibly, in other Mediterranean countries. Rift Valley Fever virus can cause serious illness in both animals and humans, leading to high morbidity and mortality, and is considered to be a potential agent for epizootics and human epidemics. Since information on this group of viruses is still scant, reliable laboratory tools for diagnosis and epidemiological surveillance must be developed, in order to ascertain their real impact on Public Health. Sequence data obtained from Spanish isolates of Toscana virus and other phleboviruses confirmed that natural genome variability may hamper the diagnosis of these agents by molecular methods, so this must be borne in mind when developing reliable assays. In view of the above, a novel and useful protocol has been developed for the detection and specific identification of every member of the phlebovirus genus present in a sample, including Toscana virus, based on a generic RT-nested-PCR, followed by sequencing of the amplified fragment. A change in this method also allowed specific direct detection and identification of wild isolates of Toscana virus of different geographical origin, using newly designed primers. Testing clinical samples with these assays confirmed the role of Toscana virus as an agent that causes acute aseptic meningitis in the central region of Spain. Copyright 2003 Wiley-Liss, Inc.

  10. Detection, identification and differentiation of Pectobacterium and Dickeya species causing potato blackleg and tuber soft rot: a review.

    Science.gov (United States)

    Czajkowski, R; Pérombelon, McM; Jafra, S; Lojkowska, E; Potrykus, M; van der Wolf, Jm; Sledz, W

    2015-01-01

    The soft rot Enterobacteriaceae (SRE) Pectobacterium and Dickeya species (formerly classified as pectinolytic Erwinia spp.) cause important diseases on potato and other arable and horticultural crops. They may affect the growing potato plant causing blackleg and are responsible for tuber soft rot in storage thereby reducing yield and quality. Efficient and cost-effective detection and identification methods are essential to investigate the ecology and pathogenesis of the SRE as well as in seed certification programmes. The aim of this review was to collect all existing information on methods available for SRE detection. The review reports on the sampling and preparation of plant material for testing and on over thirty methods to detect, identify and differentiate the soft rot and blackleg causing bacteria to species and subspecies level. These include methods based on biochemical characters, serology, molecular techniques which rely on DNA sequence amplification as well as several less-investigated ones.

  11. Detection and identification of drugs and toxicants in human body fluids by liquid chromatography-tandem mass spectrometry under data-dependent acquisition control and automated database search.

    Science.gov (United States)

    Oberacher, Herbert; Schubert, Birthe; Libiseller, Kathrin; Schweissgut, Anna

    2013-04-03

    Systematic toxicological analysis (STA) is aimed at detecting and identifying all substances of toxicological relevance (i.e. drugs, drugs of abuse, poisons and/or their metabolites) in biological material. Particularly, gas chromatography-mass spectrometry (GC/MS) represents a competent and commonly applied screening and confirmation tool. Herein, we present an untargeted liquid chromatography-tandem mass spectrometry (LC/MS/MS) assay aimed to complement existing GC/MS screening for the detection and identification of drugs in blood, plasma and urine samples. Solid-phase extraction was accomplished on mixed-mode cartridges. LC was based on gradient elution in a miniaturized C18 column. High resolution electrospray ionization-MS/MS in positive ion mode with data-dependent acquisition control was used to generate tandem mass spectral information that enabled compound identification via automated library search in the "Wiley Registry of Tandem Mass Spectral Data, MSforID". Fitness of the developed LC/MS/MS method for application in STA in terms of selectivity, detection capability and reliability of identification (sensitivity/specificity) was demonstrated with blank samples, certified reference materials, proficiency test samples, and authentic casework samples. Copyright © 2013 Elsevier B.V. All rights reserved.

  12. Spatial- and Time-Correlated Detection of Fission Fragments

    Directory of Open Access Journals (Sweden)

    Platkevic M.

    2012-02-01

    Full Text Available With the goal to measure angular correlations of fission fragments in rare fission decay (e.g. ternary and quaternary fission, a multi-detector coincidence system based on two and up to four position sensitive pixel detectors Timepix has been built. In addition to the high granularity, wide dynamic range and per pixel signal threshold, these devices are equipped with per pixel energy and time sensitivity providing more information (position, energy, time, enhances particle-type identification and selectivity of event-by-event detection. Operation of the device with the integrated USB 2.0 based readout interface FITPix and the control and data acquisition software tool Pixelman enables online visualization and flexible/adjustable operation for a different type of experiments. Spatially correlated fission fragments can be thus registered in coincidence. Similarly triggered measurements are performed using an integrated spectrometric module with analogue signal chain electronics. The current status of development together with demonstration of the technique with a 252Cf source is presented.

  13. Wide-scope analysis of pesticide and veterinary drug residues in meat matrices by high resolution MS: detection and identification using Exactive-Orbitrap.

    Science.gov (United States)

    Gómez-Pérez, María Luz; Romero-González, Roberto; Plaza-Bolaños, Patricia; Génin, Eric; Martínez Vidal, José Luis; Garrido Frenich, Antonia

    2014-01-01

    A multiresidue and multiclass method for the simultaneous determination of more than 350 compounds including pesticides, biopesticides and veterinary drugs in different meat matrices (beef, pork and chicken) by ultra-high performance liquid chromatography coupled to Orbitrap MS has been developed. In the present study, the determination of fragments was accomplished as an essential tool for a reliable identification of compounds using high resolution MS. To obtain these fragments, different strategies have been carried out in order to ensure an appropriate fragment assignment and identification. The analytical method is suitable for qualitative analysis, and it was also evaluated for quantitative analysis. Generic extraction conditions were optimized, obtaining adequate recovery and precision values for most of the studied analytes (>290). The limits of detection ranged from 2 to 16 µg kg(-1). Limits of quantification were 10 µg kg(-1) with the exception of few compounds with a higher value (50 or 100 µg kg(-1)). Limits of identification were also established, and they ranged from 2 to 150 µg kg(-1). This method was applied to the analysis of 18 meat samples and some veterinary drugs as enrofloxacin and sulfadiazine were detected and further identified/quantified (with triple quadrupole) in two different samples at 33 µg kg(-1) and trace levels, respectively. No pesticides were detected in the analyzed samples. Copyright © 2014 John Wiley & Sons, Ltd.

  14. [A capillary blood flow velocity detection system based on linear array charge-coupled devices].

    Science.gov (United States)

    Zhou, Houming; Wang, Ruofeng; Dang, Qi; Yang, Li; Wang, Xiang

    2017-12-01

    In order to detect the flow characteristics of blood samples in the capillary, this paper introduces a blood flow velocity measurement system based on field-programmable gate array (FPGA), linear charge-coupled devices (CCD) and personal computer (PC) software structure. Based on the analysis of the TCD1703C and AD9826 device data sheets, Verilog HDL hardware description language was used to design and simulate the driver. Image signal acquisition and the extraction of the real-time edge information of the blood sample were carried out synchronously in the FPGA. Then a series of discrete displacement were performed in a differential operation to scan each of the blood samples displacement, so that the sample flow rate could be obtained. Finally, the feasibility of the blood flow velocity detection system was verified by simulation and debugging. After drawing the flow velocity curve and analyzing the velocity characteristics, the significance of measuring blood flow velocity is analyzed. The results show that the measurement of the system is less time-consuming and less complex than other flow rate monitoring schemes.

  15. Counterflow Dielectrophoresis for Trypanosome Enrichment and Detection in Blood

    Science.gov (United States)

    Menachery, Anoop; Kremer, Clemens; Wong, Pui E.; Carlsson, Allan; Neale, Steven L.; Barrett, Michael P.; Cooper, Jonathan M.

    2012-10-01

    Human African trypanosomiasis or sleeping sickness is a deadly disease endemic in sub-Saharan Africa, caused by single-celled protozoan parasites. Although it has been targeted for elimination by 2020, this will only be realized if diagnosis can be improved to enable identification and treatment of afflicted patients. Existing techniques of detection are restricted by their limited field-applicability, sensitivity and capacity for automation. Microfluidic-based technologies offer the potential for highly sensitive automated devices that could achieve detection at the lowest levels of parasitemia and consequently help in the elimination programme. In this work we implement an electrokinetic technique for the separation of trypanosomes from both mouse and human blood. This technique utilises differences in polarisability between the blood cells and trypanosomes to achieve separation through opposed bi-directional movement (cell counterflow). We combine this enrichment technique with an automated image analysis detection algorithm, negating the need for a human operator.

  16. Rapid sample preparation for detection and identification of avian influenza virus from chicken faecal samples using magnetic bead microsystem

    DEFF Research Database (Denmark)

    Dhumpa, Raghuram; Bu, Minqiang; Handberg, Kurt

    2010-01-01

    Avian influenza virus (AIV) is an infectious agent of birds and mammals. AIV is causing huge economic loss and can be a threat to human health. Reverse transcriptase polymerase chain reaction (RT-PCR) has been used as a method for the detection and identification of AIV virus. Although RT...

  17. Rapid and reliable detection and identification of GM events using multiplex PCR coupled with oligonucleotide microarray.

    Science.gov (United States)

    Xu, Xiaodan; Li, Yingcong; Zhao, Heng; Wen, Si-yuan; Wang, Sheng-qi; Huang, Jian; Huang, Kun-lun; Luo, Yun-bo

    2005-05-18

    To devise a rapid and reliable method for the detection and identification of genetically modified (GM) events, we developed a multiplex polymerase chain reaction (PCR) coupled with a DNA microarray system simultaneously aiming at many targets in a single reaction. The system included probes for screening gene, species reference gene, specific gene, construct-specific gene, event-specific gene, and internal and negative control genes. 18S rRNA was combined with species reference genes as internal controls to assess the efficiency of all reactions and to eliminate false negatives. Two sets of the multiplex PCR system were used to amplify four and five targets, respectively. Eight different structure genes could be detected and identified simultaneously for Roundup Ready soybean in a single microarray. The microarray specificity was validated by its ability to discriminate two GM maizes Bt176 and Bt11. The advantages of this method are its high specificity and greatly reduced false-positives and -negatives. The multiplex PCR coupled with microarray technology presented here is a rapid and reliable tool for the simultaneous detection of GM organism ingredients.

  18. Polymer nanocomposite nanomechanical cantilever sensors: material characterization, device development and application in explosive vapour detection

    International Nuclear Information System (INIS)

    Seena, V; Fernandes, Avil; Ramgopal Rao, V; Pant, Prita; Mukherji, Soumyo

    2011-01-01

    This paper reports an optimized and highly sensitive piezoresistive SU-8 nanocomposite microcantilever sensor and its application for detection of explosives in vapour phase. The optimization has been in improving its electrical, mechanical and transduction characteristics. We have achieved a better dispersion of carbon black (CB) in the SU-8/CB nanocomposite piezoresistor and arrived at an optimal range of 8-9 vol% CB concentration by performing a systematic mechanical and electrical characterization of polymer nanocomposites. Mechanical characterization of SU-8/CB nanocomposite thin films was performed using the nanoindentation technique with an appropriate substrate effect analysis. Piezoresistive microcantilevers having an optimum carbon black concentration were fabricated using a design aimed at surface stress measurements with reduced fabrication process complexity. The optimal range of 8-9 vol% CB concentration has resulted in an improved sensitivity, low device variability and low noise level. The resonant frequency and spring constant of the microcantilever were found to be 22 kHz and 0.4 N m -1 respectively. The devices exhibited a surface stress sensitivity of 7.6 ppm (mN m -1 ) -1 and the noise characterization results support their suitability for biochemical sensing applications. This paper also reports the ability of the sensor in detecting TNT vapour concentration down to less than six parts per billion with a sensitivity of 1 mV/ppb.

  19. Polymer nanocomposite nanomechanical cantilever sensors: material characterization, device development and application in explosive vapour detection

    Energy Technology Data Exchange (ETDEWEB)

    Seena, V; Fernandes, Avil; Ramgopal Rao, V [Centre for Excellence in Nanoelectronics, Department of Electrical Engineering, Indian Institute of Technology Bombay, Mumbai, Maharashtra (India); Pant, Prita [Department of Metallurgical Engineering and Materials Science, Indian Institute of Technology Bombay, Mumbai, Maharashtra (India); Mukherji, Soumyo, E-mail: seenapradeep@iitb.ac.in, E-mail: rrao@ee.iitb.ac.in [Department of Biosciences and Bio-engineering, Indian Institute of Technology Bombay, Mumbai, Maharashtra (India)

    2011-07-22

    This paper reports an optimized and highly sensitive piezoresistive SU-8 nanocomposite microcantilever sensor and its application for detection of explosives in vapour phase. The optimization has been in improving its electrical, mechanical and transduction characteristics. We have achieved a better dispersion of carbon black (CB) in the SU-8/CB nanocomposite piezoresistor and arrived at an optimal range of 8-9 vol% CB concentration by performing a systematic mechanical and electrical characterization of polymer nanocomposites. Mechanical characterization of SU-8/CB nanocomposite thin films was performed using the nanoindentation technique with an appropriate substrate effect analysis. Piezoresistive microcantilevers having an optimum carbon black concentration were fabricated using a design aimed at surface stress measurements with reduced fabrication process complexity. The optimal range of 8-9 vol% CB concentration has resulted in an improved sensitivity, low device variability and low noise level. The resonant frequency and spring constant of the microcantilever were found to be 22 kHz and 0.4 N m{sup -1} respectively. The devices exhibited a surface stress sensitivity of 7.6 ppm (mN m{sup -1}){sup -1} and the noise characterization results support their suitability for biochemical sensing applications. This paper also reports the ability of the sensor in detecting TNT vapour concentration down to less than six parts per billion with a sensitivity of 1 mV/ppb.

  20. Polymer nanocomposite nanomechanical cantilever sensors: material characterization, device development and application in explosive vapour detection.

    Science.gov (United States)

    Seena, V; Fernandes, Avil; Pant, Prita; Mukherji, Soumyo; Rao, V Ramgopal

    2011-07-22

    This paper reports an optimized and highly sensitive piezoresistive SU-8 nanocomposite microcantilever sensor and its application for detection of explosives in vapour phase. The optimization has been in improving its electrical, mechanical and transduction characteristics. We have achieved a better dispersion of carbon black (CB) in the SU-8/CB nanocomposite piezoresistor and arrived at an optimal range of 8-9 vol% CB concentration by performing a systematic mechanical and electrical characterization of polymer nanocomposites. Mechanical characterization of SU-8/CB nanocomposite thin films was performed using the nanoindentation technique with an appropriate substrate effect analysis. Piezoresistive microcantilevers having an optimum carbon black concentration were fabricated using a design aimed at surface stress measurements with reduced fabrication process complexity. The optimal range of 8-9 vol% CB concentration has resulted in an improved sensitivity, low device variability and low noise level. The resonant frequency and spring constant of the microcantilever were found to be 22 kHz and 0.4 N m(-1) respectively. The devices exhibited a surface stress sensitivity of 7.6 ppm (mN m(-1))(-1) and the noise characterization results support their suitability for biochemical sensing applications. This paper also reports the ability of the sensor in detecting TNT vapour concentration down to less than six parts per billion with a sensitivity of 1 mV/ppb.

  1. Automatic detection of patient identification and positioning errors in radiation therapy treatment using 3-dimensional setup images.

    Science.gov (United States)

    Jani, Shyam S; Low, Daniel A; Lamb, James M

    2015-01-01

    To develop an automated system that detects patient identification and positioning errors between 3-dimensional computed tomography (CT) and kilovoltage CT planning images. Planning kilovoltage CT images were collected for head and neck (H&N), pelvis, and spine treatments with corresponding 3-dimensional cone beam CT and megavoltage CT setup images from TrueBeam and TomoTherapy units, respectively. Patient identification errors were simulated by registering setup and planning images from different patients. For positioning errors, setup and planning images were misaligned by 1 to 5 cm in the 6 anatomical directions for H&N and pelvis patients. Spinal misalignments were simulated by misaligning to adjacent vertebral bodies. Image pairs were assessed using commonly used image similarity metrics as well as custom-designed metrics. Linear discriminant analysis classification models were trained and tested on the imaging datasets, and misclassification error (MCE), sensitivity, and specificity parameters were estimated using 10-fold cross-validation. For patient identification, our workflow produced MCE estimates of 0.66%, 1.67%, and 0% for H&N, pelvis, and spine TomoTherapy images, respectively. Sensitivity and specificity ranged from 97.5% to 100%. MCEs of 3.5%, 2.3%, and 2.1% were obtained for TrueBeam images of the above sites, respectively, with sensitivity and specificity estimates between 95.4% and 97.7%. MCEs for 1-cm H&N/pelvis misalignments were 1.3%/5.1% and 9.1%/8.6% for TomoTherapy and TrueBeam images, respectively. Two-centimeter MCE estimates were 0.4%/1.6% and 3.1/3.2%, respectively. MCEs for vertebral body misalignments were 4.8% and 3.6% for TomoTherapy and TrueBeam images, respectively. Patient identification and gross misalignment errors can be robustly and automatically detected using 3-dimensional setup images of different energies across 3 commonly treated anatomical sites. Copyright © 2015 American Society for Radiation Oncology. Published by

  2. Functionality of road safety devicesidentification and analysis of factors

    Directory of Open Access Journals (Sweden)

    Jeliński Łukasz

    2017-01-01

    Full Text Available Road safety devices are designed to protect road users from the risk of injury or death. The principal type of restraint is the safety barrier. Deployed on sites with the highest risk of run-off-road accidents, safety barriers are mostly found on bridges, flyovers, central reservations, and on road edges which have fixed obstacles next to them. If properly designed and installed, safety barriers just as other road safety devices, should meet a number of functional features. This report analyses factors which may deteriorate functionality, ways to prevent this from happening and the thresholds for loss of road safety device functionality.

  3. The Performance of the Four Anaerobic Blood Culture Bottles BacT/ALERT-FN, -FN Plus, BACTEC-Plus and -Lytic in Detection of Anaerobic Bacteria and Identification by Direct MALDI-TOF MS.

    Science.gov (United States)

    Almuhayawi, Mohammed; Altun, Osman; Abdulmajeed, Adam Dilshad; Ullberg, Måns; Özenci, Volkan

    2015-01-01

    Detection and identification of anaerobic bacteria in blood cultures (BC) is a well-recognized challenge in clinical microbiology. We studied 100 clinical anaerobic BC isolates to evaluate the performance of BacT/ALERT-FN, -FN Plus (BioMérieux), BACTEC-Plus and -Lytic (Becton Dickinson BioSciences) BC bottles in detection and time to detection (TTD) of anaerobic bacteria. BACTEC Lytic had higher detection rate (94/100, 94%) than BacT/ALERT FN Plus (80/100, 80%) (panaerobic bacteria among the remaining bottle types. The 67 anaerobic bacteria that signalled positive in all four bottle types were analyzed to compare the time to detection (TTD) and isolates were directly identified by MALDI-TOF MS. There was a significant difference in TTD among the four bottle types (panaerobic BC bottles are equally suitable for direct MALDI-TOF MS for rapid and reliable identification of common anaerobic bacteria. Further clinical studies are warranted to investigate the performance of anaerobic BC bottles in detection of anaerobic bacteria and identification by direct MALDI-TOF MS.

  4. CRIM-TRACK: sensor system for detection of criminal chemical substances

    Science.gov (United States)

    Munk, Jens K.; Buus, Ole T.; Larsen, Jan; Dossi, Eleftheria; Tatlow, Sol; Lässig, Lina; Sandström, Lars; Jakobsen, Mogens H.

    2015-10-01

    Detection of illegal compounds requires a reliable, selective and sensitive detection device. The successful device features automated target acquisition, identification and signal processing. It is portable, fast, user friendly, sensitive, specific, and cost efficient. LEAs are in need of such technology. CRIM-TRACK is developing a sensing device based on these requirements. We engage highly skilled specialists from research institutions, industry, SMEs and LEAs and rely on a team of end users to benefit maximally from our prototypes. Currently we can detect minute quantities of drugs, explosives and precursors thereof in laboratory settings. Using colorimetric technology we have developed prototypes that employ disposable sensing chips. Ease of operation and intuitive sensor response are highly prioritized features that we implement as we gather data to feed into machine learning. With machine learning our ability to detect threat compounds amidst harmless substances improves. Different end users prefer their equipment optimized for their specific field. In an explosives-detecting scenario, the end user may prefer false positives over false negatives, while the opposite may be true in a drug-detecting scenario. Such decisions will be programmed to match user preference. Sensor output can be as detailed as the sensor allows. The user can be informed of the statistics behind the detection, identities of all detected substances, and quantities thereof. The response can also be simplified to "yes" vs. "no". The technology under development in CRIM-TRACK will provide custom officers, police and other authorities with an effective tool to control trafficking of illegal drugs and drug precursors.

  5. Reactor noise monitoring device

    International Nuclear Information System (INIS)

    Yamanaka, Hiroto.

    1990-01-01

    The present invention concerns a reactor noise monitoring device by detecting abnormal sounds in background noises. Vibration sounds detected by accelerometers are applied to a loose parts detector. The detector generates high alarm if there are sudden impact sounds in the background noises and applies output signals to an accumulation device. If there is slight impact sounds in the vicinity of any of the accelerometers, the accumulation device accumulates the abnormal sounds assumed to be generated from an identical site while synchronizing the waveforms for all of the channels. Then, the device outputs signals in which the background noises are cancelled, as detection signals. Therefore, S/N ratio can be improved and the abnormal sounds contained in the background noises can be detected, to thereby improve the accuracy for estimating the position where the abnormal sounds are generated. (I.S.)

  6. Detecting cavitation in vivo from shock-wave therapy devices

    Science.gov (United States)

    Matula, Thomas J.; Yu, Jinfei; Bailey, Michael R.

    2005-04-01

    Extracorporeal shock-wave therapy (ESWT) has been used as a treatment for plantar faciitis, lateral epicondylitis, shoulder tendonitis, non-unions, and other indications where conservative treatments have been unsuccessful. However, in many areas, the efficacy of SW treatment has not been well established, and the mechanism of action, particularly the role of cavitation, is not well understood. Research indicates cavitation plays an important role in other ultrasound therapies, such as lithotripsy and focused ultrasound surgery, and in some instances, cavitation has been used as a means to monitor or detect a biological effect. Although ESWT can generate cavitation easily in vitro, it is unknown whether or not cavitation is a significant factor in vivo. The purpose of this investigation is to use diagnostic ultrasound to detect and monitor cavitation generated by ESWT devices in vivo. Diagnostic images are collected at various times during and after treatment. The images are then post-processed with image-processing algorithms to enhance the contrast between bubbles and surrounding tissue. The ultimate goal of this research is to utilize cavitation as a means for optimizing shock wave parameters such as amplitude and pulse repetition frequency. [Work supported by APL internal funds and NIH DK43881 and DK55674.

  7. A biometric approach to laboratory rodent identification.

    Science.gov (United States)

    Cameron, Jens; Jacobson, Christina; Nilsson, Kenneth; Rögnvaldsson, Thorsteinn

    2007-03-01

    Individual identification of laboratory rodents typically involves invasive methods, such as tattoos, ear clips, and implanted transponders. Beyond the ethical dilemmas they may present, these methods may cause pain or distress that confounds research results. The authors describe a prototype device for biometric identification of laboratory rodents that would allow researchers to identify rodents without the complications of other methods. The device, which uses the rodent's ear blood vessel pattern as the identifier, is fast, automatic, noninvasive, and painless.

  8. The search for a standard model Higgs at the LHC and electron identification using transition radiation in the ATLAS tracker

    International Nuclear Information System (INIS)

    Egede, U.

    1998-01-01

    The large Hadron Collider (LHC) will be ready for proton-proton collisions in the year 2005 and the ATLAS detector will be one of the two experiments at the LHC which will explore a new and higher energy range for particle physics. In this thesis, an analysis of the power of the ATLAS detector to detect a Standard Model Higgs boson has been performed. It is shown that it will be possible to discover a Higgs particle across the complete mass range from the lower limit defined by the reach of the LEP2 collider experiments to the upper theoretical limit around 1 TeV. The role of the inner tracking detector of ATLAS for the detection of conversions and the identification of the primary vertex in the detection of a Higgs particle in the Higgs to two photon decay channel is demonstrated with a detailed detector simulation. The identification of a 1 TeV Higgs particle requires a good understanding of both the signal and the backgrounds. The related uncertainties are covered in detail and it is shown that the Higgs can be identified in the H→WW→lvjj, H→ZZ→llvv and H→ZZ→lljj decay channels. The Transition Radiation Tracker (TRT) is a combined tracking and electron identification device which will be a part of the inner tracking detector of ATLAS. For a prototype of the TRT the electron identification performance is analysed and it is shown that the full scale TRT together with the calorimeters will provide the electron identification power required for a clean electron and photon signal at the LHC. For the prototype a rejection factor of 100 against pions was achieved with an electron efficiency of 90%. the importance of the TRT for a clear detection of a Higgs particle is demonstrated

  9. The search for a standard model Higgs at the LHC and electron identification using transition radiation in the ATLAS tracker

    Energy Technology Data Exchange (ETDEWEB)

    Egede, U.

    1998-01-01

    The large Hadron Collider (LHC) will be ready for proton-proton collisions in the year 2005 and the ATLAS detector will be one of the two experiments at the LHC which will explore a new and higher energy range for particle physics. In this thesis, an analysis of the power of the ATLAS detector to detect a Standard Model Higgs boson has been performed. It is shown that it will be possible to discover a Higgs particle across the complete mass range from the lower limit defined by the reach of the LEP2 collider experiments to the upper theoretical limit around 1 TeV. The role of the inner tracking detector of ATLAS for the detection of conversions and the identification of the primary vertex in the detection of a Higgs particle in the Higgs to two photon decay channel is demonstrated with a detailed detector simulation. The identification of a 1 TeV Higgs particle requires a good understanding of both the signal and the backgrounds. The related uncertainties are covered in detail and it is shown that the Higgs can be identified in the H{yields}WW{yields}lvjj, H{yields}ZZ{yields}llvv and H{yields}ZZ{yields}lljj decay channels. The Transition Radiation Tracker (TRT) is a combined tracking and electron identification device which will be a part of the inner tracking detector of ATLAS. For a prototype of the TRT the electron identification performance is analysed and it is shown that the full scale TRT together with the calorimeters will provide the electron identification power required for a clean electron and photon signal at the LHC. For the prototype a rejection factor of 100 against pions was achieved with an electron efficiency of 90%. the importance of the TRT for a clear detection of a Higgs particle is demonstrated. 82 refs, figs, tabs.

  10. Access control and personal identification systems

    CERN Document Server

    Bowers, Dan M

    1988-01-01

    Access Control and Personal Identification Systems provides an education in the field of access control and personal identification systems, which is essential in selecting the appropriate equipment, dealing intelligently with vendors in purchases of the equipment, and integrating the equipment into a total effective system. Access control devices and systems comprise an important part of almost every security system, but are seldom the sole source of security. In order for the goals of the total system to be met, the other portions of the security system must also be well planned and executed

  11. Radiated EMC immunity investigation of common recognition identification platform for medical applications

    Science.gov (United States)

    Miranda, Jorge; Cabral, Jorge; Ravelo, Blaise; Wagner, Stefan; Pedersen, Christian F.; Memon, Mukhtiar; Mathiesen, Morten

    2015-01-01

    An innovative e-healthcare platform named common recognition and identification platform (CRIP) was developed and tested as part of the CareStore project. CareStore and CRIP aims at delivering accurate and safe disease management by minimising human operator errors in hospitals and care facilities. To support this, the CRIP platform features fingerprint biometrics and near field communication (NFC) for user identification; and Bluetooth communication support for a range of telemedicine medical devices adhering to the IEEE 11073 standard. The aim of this study was to evaluate the electromagnetic compatibility (EMC) immunity of the CRIP platform in order to validate it for medical application use. The first prototype of CRIP was demonstrated to operate as expected by showing the user identification function feasibility, both via NFC and biometric, and by detection of Bluetooth devices via radio frequency (RF) scanning. The NFC module works in the 13.56 MHz band and the Bluetooth module work in the 2.4 GHz band, according to the IEEE 802.15.1 standard. The standard test qualification of the CRIP was performed based on the radiated EMC immunity with respect to the EN 61000-4-3 standard. The immunity tests were conducted under industrial EMC compliance with electric field aggression, with levels up to 10 V/m in both horizontal and vertical polarisations when the test antenna and the CRIP were placed at a distance of 3 m. It was found that the CRIP device complies with the European electromagnetic (EM) radiation immunity requirements.

  12. Device fabrication, characterization, and thermal neutron detection response of LiZnP and LiZnAs semiconductor devices

    Energy Technology Data Exchange (ETDEWEB)

    Montag, Benjamin W., E-mail: bmontag@ksu.edu; Ugorowski, Philip B.; Nelson, Kyle A.; Edwards, Nathaniel S.; McGregor, Douglas S.

    2016-11-11

    Nowotny-Juza compounds continue to be explored as candidates for solid-state neutron detectors. Such a device would have greater efficiency, in a compact form, than present day gas-filled {sup 3}He and {sup 10}BF{sub 3} detectors. The {sup 6}Li(n,t){sup 4}He reaction yields a total Q-value of 4.78 MeV, larger than {sup 10}B, an energy easily identified above background radiations. Hence, devices fabricated from semiconductor compounds having either natural Li (nominally 7.5% {sup 6}Li) or enriched {sup 6}Li (usually 95% {sup 6}Li) as constituent atoms may provide a material for compact high efficiency neutron detectors. Starting material was synthesized by preparing equimolar portions of Li, Zn, and As sealed under vacuum (10{sup −6} Torr) in quartz ampoules lined with boron nitride and subsequently reacted in a compounding furnace [1]. The raw synthesized material indicated the presence high impurity levels (material and electrical property characterizations). A static vacuum sublimation in quartz was performed to help purify the synthesized material [2,3]. Bulk crystalline samples were grown from the purified material [4,5]. Samples were cut using a diamond wire saw, and processed into devices. Bulk resistivity was determined from I–V curve measurements, ranging from 10{sup 6}–10{sup 11} Ω cm. Devices were characterized for sensitivity to 5.48 MeV alpha particles, 337 nm laser light, and neutron sensitivity in a thermal neutron diffracted beam at the Kansas State University TRIGA Mark II nuclear reactor. Thermal neutron reaction product charge induction was measured with a LiZnP device, and the reaction product spectral response was observed. - Highlights: • Devices were fabricated from in-house synthesized and purified LiZnAs and LiZnP. • Devices ranged in bulk resistivity from 10{sup 6}–10{sup 11} Ω cm. • Devices showed sensitivity to 5.48 MeV alpha particles. • Devices were characterized with a 337 nm laser light. • Devices were evaluated

  13. Portable and low-cost colorimetric office paper-based device for phenacetin detection in seized cocaine samples.

    Science.gov (United States)

    da Silva, Gabriela O; de Araujo, William R; Paixão, Thiago R L C

    2018-01-01

    An office paper-based colorimetric device is proposed as a portable, rapid, and low-cost sensor for forensic applications aiming to detect phenacetin used as adulterant in illicit seized materials such as cocaine. The proposed method uses white office paper as the substrate and wax printing technology to fabricate the detection zones. Based on the optimum conditions, a linear analytical curve was obtained for phenacetin concentrations ranging from 0 to 64.52µgmL ‒1 , and the straight line was in accordance with the following equation: (Magenta percentage color) = 1.19 + 0.458 (C Phe /µgmL ‒1 ), R 2 = 0.990. The limit of detection was calculated as 3.5µgmL ‒1 (3σ/slope). The accuracy of the proposed method was evaluated using real seized cocaine samples and the spike-recovery procedure. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. Development of acoustic partial discharge detection device; Bubun hoden kenshutsusochi wo riyo shita onkyo niyoru hendensetsubi no zetsuen rekka shindan gijutsu no kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    Suenaga, Kiyoka [Kawasaki Steel Corp., Tokyo (Japan)

    1999-06-15

    This paper introduces an acoustic partial discharge detection device, consisting of a microphone, amplifier circuit for analog signals, A/D (Digital Signal Processor). This device has the following unique characteristics: (1) Judging whether or not there is partial discharge by analyzing supersonic signals. (2) High sensitivity for detecting discharge ; 100 pC from a distance of 1.2 m. (3)Locating the position of discharge occurrence by using a sharpe directional parabola microphone and laser beam pointer. The detector was used in the steel works to detect partial discharge on high-voltage electrical apparatus, where faults due to partial discharge were found in the potential transformer and current transformer. The effectiveness of the device was thus verified. (author)

  15. Hardware device binding and mutual authentication

    Science.gov (United States)

    Hamlet, Jason R; Pierson, Lyndon G

    2014-03-04

    Detection and deterrence of device tampering and subversion by substitution may be achieved by including a cryptographic unit within a computing device for binding multiple hardware devices and mutually authenticating the devices. The cryptographic unit includes a physically unclonable function ("PUF") circuit disposed in or on the hardware device, which generates a binding PUF value. The cryptographic unit uses the binding PUF value during an enrollment phase and subsequent authentication phases. During a subsequent authentication phase, the cryptographic unit uses the binding PUF values of the multiple hardware devices to generate a challenge to send to the other device, and to verify a challenge received from the other device to mutually authenticate the hardware devices.

  16. Indoor Navigation Design Integrated with Smart Phones and Rfid Devices

    Science.gov (United States)

    Ortakci, Y.; Demiral, E.; Atila, U.; Karas, I. R.

    2015-10-01

    High rise, complex and huge buildings in the cities are almost like a small city with their tens of floors, hundreds of corridors and rooms and passages. Due to size and complexity of these buildings, people need guidance to find their way to the destination in these buildings. In this study, a mobile application is developed to visualize pedestrian's indoor position as 3D in their smartphone and RFID Technology is used to detect the position of pedestrian. While the pedestrian is walking on his/her way on the route, smartphone will guide the pedestrian by displaying the photos of indoor environment on the route. Along the tour, an RFID (Radio-Frequency Identification) device is integrated to the system. The pedestrian will carry the RFID device during his/her tour in the building. The RFID device will send the position data to the server directly in every two seconds periodically. On the other side, the pedestrian will just select the destination point in the mobile application on smartphone and sent the destination point to the server. The shortest path from the pedestrian position to the destination point is found out by the script on the server. This script also sends the environment photo of the first node on the acquired shortest path to the client as an indoor navigation module.

  17. Rapid Diagnostic Device for Subclinical Mastitis Based on Electrochemical Detection of Superoxide Produced from Neutrophils in Fresh Milk

    Science.gov (United States)

    Okada, Kohei; Fukuda, Junji; Suzuki, Hiroaki

    Electrochemical microdevices were fabricated to identify mastitic cows based on the increased number of neutrophils in raw milk. Because neutrophils produce superoxide (O2·-), the amount of O2·- can be used as an early indicator for subclinical mastitis. In the microdevices, O2·- was detected on a gold electrode using superoxide dismutase immobilized via a self-assembled monolayer of cysteine. In a preliminary test using xanthine oxidase to produce O2·-, one of the devices detected the production and rapid extinction of O2·-. When neutrophils obtained from a mastitic cow were concentrated by centrifugation and introduced into the device, a current increase distinctly different from the background was observed. Furthermore, a micropillar structure was fabricated on the gold electrode to trap and collect neutrophils, thereby facilitating the concentration of these cells around the electrode. The measured current clearly depended on the number of neutrophils in raw milk samples, demonstrating the applicability of the device for rapid diagnosis of subclinical mastitis.

  18. Rapid, Sensitive, and Reusable Detection of Glucose by a Robust Radiofrequency Integrated Passive Device Biosensor Chip

    Science.gov (United States)

    Kim, Nam-Young; Adhikari, Kishor Kumar; Dhakal, Rajendra; Chuluunbaatar, Zorigt; Wang, Cong; Kim, Eun-Soo

    2015-01-01

    Tremendous demands for sensitive and reliable label-free biosensors have stimulated intensive research into developing miniaturized radiofrequency resonators for a wide range of biomedical applications. Here, we report the development of a robust, reusable radiofrequency resonator based integrated passive device biosensor chip fabricated on a gallium arsenide substrate for the detection of glucose in water-glucose solutions and sera. As a result of the highly concentrated electromagnetic energy between the two divisions of an intertwined spiral inductor coupled with an interdigital capacitor, the proposed glucose biosensor chip exhibits linear detection ranges with high sensitivity at center frequency. This biosensor, which has a sensitivity of up to 199 MHz/mgmL−1 and a short response time of less than 2 sec, exhibited an ultralow detection limit of 0.033 μM and a reproducibility of 0.61% relative standard deviation. In addition, the quantities derived from the measured S-parameters, such as the propagation constant (γ), impedance (Z), resistance (R), inductance (L), conductance (G) and capacitance (C), enabled the effective multi-dimensional detection of glucose. PMID:25588958

  19. Integrated Circuits for Rapid Sample Processing and Electrochemical Detection of Biomarkers

    Science.gov (United States)

    Besant, Justin

    The trade-off between speed and sensitivity of detection is a fundamental challenge in the design of point-of-care diagnostics. As the relevant molecules in many diseases exist natively at extremely low levels, many gold-standard diagnostic tests are designed with high sensitivity at the expense of long incubations needed to amplify the target analytes. The central aim of this thesis is to design new strategies to detect biologically relevant analytes with both high speed and sensitivity. The response time of a biosensor is limited by the ability of the target analyte to accumulate to detectable levels at the sensor surface. We overcome this limitation by designing a range of integrated devices to optimize the flux of the analyte to the sensor by increasing the effective analyte concentration, shortening the required diffusion distance, and confining the analyte in close proximity to the sensor. We couple these devices with novel ultrasensitive electrochemical transduction strategies to convert rare analytes into a detectable signal. We showcase the clinical utility of these approaches with several applications including cancer diagnosis, bacterial identification, and antibiotic susceptibility profiling. We design and optimize a device to isolate rare cancer cells from the bloodstream with near 100% efficiency and 10 000-fold specificity. We analyse pathogen specific nucleic acids by lysing bacteria in close proximity to an electrochemical sensor and find that this approach has 10-fold higher sensitivity than standard lysis in bulk solution. We design an electronic chip to readout the antibiotic susceptibility profile with an hour-long incubation by concentrating bacteria into nanoliter chambers with integrated electrodes. Finally, we report a strategy for ultrasensitive visual readout of nucleic acids as low as 100 fM within 10 minutes using an amplification cascade. The strategies presented could guide the development of fast, sensitive and low-cost diagnostics

  20. Detection and identification of dyes in blue writing inks by LC-DAD-orbitrap MS.

    Science.gov (United States)

    Sun, Qiran; Luo, Yiwen; Yang, Xu; Xiang, Ping; Shen, Min

    2016-04-01

    In the field of forensic questioned document examination, to identify dyes detected in inks not only provides a solid foundation for ink discrimination in forged contents identification, but also facilitates the investigation of ink origin or the study regarding ink dating. To detect and identify potential acid and basic dyes in blue writing inks, a liquid chromatography-diode array detection-Orbitrap mass spectrometry (LC-DAD-Orbitrap MS) method was established. Three sulfonic acid dyes (Acid blue 1, Acid blue 9 and Acid red 52) and six triphenylmethane basic dyes (Ethyl violet, Crystal violet, Methyl violet 2B, Basic blue 7, Victoria blue B and Victoria blue R) were employed as reference dyes for method development. Determination of the nine dyes was validated to evaluate the instrument performance, and it turned out to be sensitive and stable enough for quantification. The method was then applied in the screening analysis of ten blue roller ball pen inks and twenty blue ballpoint pen inks. As a result, including TPR (a de-methylated product of Crystal violet), ten known dyes and four unknown dyes were detected in the inks. The latter were further identified as a de-methylated product of Victoria blue B, Acid blue 104, Acid violet 49 and Acid blue 90, through analyzing their characteristic precursor and product ions acquired by Orbitrap MS with good mass accuracy. The results showed that the established method is capable of detecting and identifying potential dyes in blue writing inks. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  1. Fault localization and analysis in semiconductor devices with optical-feedback infrared confocal microscopy

    International Nuclear Information System (INIS)

    Sarmiento, Raymund; Cemine, Vernon Julius; Tagaca, Imee Rose; Salvador, Arnel; Mar Blanca, Carlo; Saloma, Caesar

    2007-01-01

    We report on a cost-effective optical setup for characterizing light-emitting semiconductor devices with optical-feedback confocal infrared microscopy and optical beam-induced resistance change.We utilize the focused beam from an infrared laser diode to induce local thermal resistance changes across the surface of a biased integrated circuit (IC) sample. Variations in the multiple current paths are mapped by scanning the IC across the focused beam. The high-contrast current maps allow accurate differentiation of the functional and defective sites, or the isolation of the surface-emittingp-i-n devices in the IC. Optical beam-induced current (OBIC) is not generated since the incident beam energy is lower than the bandgap energy of the p-i-n device. Inhomogeneous current distributions in the IC become apparent without the strong OBIC background. They are located at a diffraction-limited resolution by referencing the current maps against the confocal reflectance image that is simultaneously acquired via optical-feedback detection. Our technique permits the accurate identification of metal and semiconductor sites as well as the classification of different metallic structures according to thickness, composition, or spatial inhomogeneity

  2. The Detection of Helicobacter hepaticus Using Whispering-Gallery Mode Microcavity Optical Sensors

    Directory of Open Access Journals (Sweden)

    Mark E. Anderson

    2015-08-01

    Full Text Available Current bacterial detection techniques are relatively slow, require bulky instrumentation, and usually require some form of specialized training. The gold standard for bacterial detection is culture testing, which can take several days to receive a viable result. Therefore, simpler detection techniques that are both fast and sensitive could greatly improve bacterial detection and identification. Here, we present a new method for the detection of the bacteria Helicobacter hepaticus using whispering-gallery mode (WGM optical microcavity-based sensors. Due to minimal reflection losses and low material adsorption, WGM-based sensors have ultra-high quality factors, resulting in high-sensitivity sensor devices. In this study, we have shown that bacteria can be non-specifically detected using WGM optical microcavity-based sensors. The minimum detection for the device was 1 × 104 cells/mL, and the minimum time of detection was found to be 750 s. Given that a cell density as low as 1 × 103 cells/mL for Helicobacter hepaticus can cause infection, the limit of detection shown here would be useful for most levels where Helicobacter hepaticus is biologically relevant. This study suggests a new approach for H. hepaticus detection using label-free optical sensors that is faster than, and potentially as sensitive as, standard techniques.

  3. Induced Voltages Ratio-Based Algorithm for Fault Detection, and Faulted Phase and Winding Identification of a Three-Winding Power Transformer

    Directory of Open Access Journals (Sweden)

    Byung Eun Lee

    2014-09-01

    Full Text Available This paper proposes an algorithm for fault detection, faulted phase and winding identification of a three-winding power transformer based on the induced voltages in the electrical power system. The ratio of the induced voltages of the primary-secondary, primary-tertiary and secondary-tertiary windings is the same as the corresponding turns ratio during normal operating conditions, magnetic inrush, and over-excitation. It differs from the turns ratio during an internal fault. For a single phase and a three-phase power transformer with wye-connected windings, the induced voltages of each pair of windings are estimated. For a three-phase power transformer with delta-connected windings, the induced voltage differences are estimated to use the line currents, because the delta winding currents are practically unavailable. Six detectors are suggested for fault detection. An additional three detectors and a rule for faulted phase and winding identification are presented as well. The proposed algorithm can not only detect an internal fault, but also identify the faulted phase and winding of a three-winding power transformer. The various test results with Electromagnetic Transients Program (EMTP-generated data show that the proposed algorithm successfully discriminates internal faults from normal operating conditions including magnetic inrush and over-excitation. This paper concludes by implementing the algorithm into a prototype relay based on a digital signal processor.

  4. An Analysis on Sensor Locations of the Human Body for Wearable Fall Detection Devices: Principles and Practice

    Directory of Open Access Journals (Sweden)

    Ahmet Turan Özdemir

    2016-07-01

    Full Text Available Wearable devices for fall detection have received attention in academia and industry, because falls are very dangerous, especially for elderly people, and if immediate aid is not provided, it may result in death. However, some predictive devices are not easily worn by elderly people. In this work, a huge dataset, including 2520 tests, is employed to determine the best sensor placement location on the body and to reduce the number of sensor nodes for device ergonomics. During the tests, the volunteer’s movements are recorded with six groups of sensors each with a triaxial (accelerometer, gyroscope and magnetometer sensor, which is placed tightly on different parts of the body with special straps: head, chest, waist, right-wrist, right-thigh and right-ankle. The accuracy of individual sensor groups with their location is investigated with six machine learning techniques, namely the k-nearest neighbor (k-NN classifier, Bayesian decision making (BDM, support vector machines (SVM, least squares method (LSM, dynamic time warping (DTW and artificial neural networks (ANNs. Each technique is applied to single, double, triple, quadruple, quintuple and sextuple sensor configurations. These configurations create 63 different combinations, and for six machine learning techniques, a total of 63 × 6 = 378 combinations is investigated. As a result, the waist region is found to be the most suitable location for sensor placement on the body with 99.96% fall detection sensitivity by using the k-NN classifier, whereas the best sensitivity achieved by the wrist sensor is 97.37%, despite this location being highly preferred for today’s wearable applications.

  5. An Analysis on Sensor Locations of the Human Body for Wearable Fall Detection Devices: Principles and Practice.

    Science.gov (United States)

    Özdemir, Ahmet Turan

    2016-07-25

    Wearable devices for fall detection have received attention in academia and industry, because falls are very dangerous, especially for elderly people, and if immediate aid is not provided, it may result in death. However, some predictive devices are not easily worn by elderly people. In this work, a huge dataset, including 2520 tests, is employed to determine the best sensor placement location on the body and to reduce the number of sensor nodes for device ergonomics. During the tests, the volunteer's movements are recorded with six groups of sensors each with a triaxial (accelerometer, gyroscope and magnetometer) sensor, which is placed tightly on different parts of the body with special straps: head, chest, waist, right-wrist, right-thigh and right-ankle. The accuracy of individual sensor groups with their location is investigated with six machine learning techniques, namely the k-nearest neighbor (k-NN) classifier, Bayesian decision making (BDM), support vector machines (SVM), least squares method (LSM), dynamic time warping (DTW) and artificial neural networks (ANNs). Each technique is applied to single, double, triple, quadruple, quintuple and sextuple sensor configurations. These configurations create 63 different combinations, and for six machine learning techniques, a total of 63 × 6 = 378 combinations is investigated. As a result, the waist region is found to be the most suitable location for sensor placement on the body with 99.96% fall detection sensitivity by using the k-NN classifier, whereas the best sensitivity achieved by the wrist sensor is 97.37%, despite this location being highly preferred for today's wearable applications.

  6. [Development and application of real-time PCR for identification and detection of horse meat in animal-origin products].

    Science.gov (United States)

    Li, Nan; Wang, Jiahui; Shen, Qing; Han, Chunhui; Zhang, Jing; Li, Fengqin; Xu, Jin; Jiang, Tao

    2013-11-01

    To develop a real-time PCR method for identification and detection of domestic horse meat (Equus caballus) in animal-origin products. The primer and TaqMan-probe was designed and synthesized according to the EU reference laboratory and 87 bp fragments was amplified for horse ingredients. The specificity and sensitivity was tested by artificially spiked horse meat into other domestic meat, such as cattle, sheep, pork, chicken, duck and rabbit. 122 samples of cattle and sheep products were random collected in Beijing market and the detection of horse meat was carried out. The real-time PCR in this study has high specificity and sensitivity for horse meat. No cross-reaction was observed between the horse and sheep, pork, chicken, duck and rabbit meat. There was little cross reaction between horse and cattle when the CT value reach 33. 81. The method can detect 0.1% of horse meat mixed with other domestic animal-origin products. No horse meat ingredients were detected in 122 samples in this survey. There was no horse meat mixed into cattle and sheep products in Beijing marked.

  7. Development and validation of a multiplex real-time PCR method to simultaneously detect 47 targets for the identification of genetically modified organisms.

    Science.gov (United States)

    Cottenet, Geoffrey; Blancpain, Carine; Sonnard, Véronique; Chuah, Poh Fong

    2013-08-01

    Considering the increase of the total cultivated land area dedicated to genetically modified organisms (GMO), the consumers' perception toward GMO and the need to comply with various local GMO legislations, efficient and accurate analytical methods are needed for their detection and identification. Considered as the gold standard for GMO analysis, the real-time polymerase chain reaction (RTi-PCR) technology was optimised to produce a high-throughput GMO screening method. Based on simultaneous 24 multiplex RTi-PCR running on a ready-to-use 384-well plate, this new procedure allows the detection and identification of 47 targets on seven samples in duplicate. To comply with GMO analytical quality requirements, a negative and a positive control were analysed in parallel. In addition, an internal positive control was also included in each reaction well for the detection of potential PCR inhibition. Tested on non-GM materials, on different GM events and on proficiency test samples, the method offered high specificity and sensitivity with an absolute limit of detection between 1 and 16 copies depending on the target. Easy to use, fast and cost efficient, this multiplex approach fits the purpose of GMO testing laboratories.

  8. Efficacy of light based detection systems for early detection of oral cancer and oral potentially malignant disorders: Systematic review.

    Science.gov (United States)

    Nagi, R; Reddy-Kantharaj, Y-B; Rakesh, N; Janardhan-Reddy, S; Sahu, S

    2016-07-01

    Earlier detection of oral squamous cell carcinoma (OSCC) and oral potentially malignant disorders (OPMD) is essential for dental professionals to improve patient survival rates. The aim of this systematic review is to to evaluate the effectiveness of devices that utilise the principles of chemiluminescence and tissue autofluorescence as adjuncts in the detection of OSCC and OPMD. The electronic retrieval systems and databases searched for relevant articles were PubMed [MEDLINE] and Science direct. The search was for limited articles published in English or with an English abstract and articles published during the period from January 2005 to April 2014. Clinical trials utilized ViziLite, Microlux TM/DL and Visual Enhanced Light scope (VELscope) for early detection of OPMD and OSCC. Twenty primary studies published satisfied our criteria for selection - 10 utilised chemiluminescence and 10 tissue autofluorescence. Senstivity of Vizilite for detecting OSCC nad OPMD ranged from 77.1 % to 100% and specificity was low that ranged from 0% to 27.8%.Most have shown that chemiluminescence increases the brightness and margins of oral mucosal white lesions and thus assist in identification of mucosal lesions not considered under Conventional visual examination. However, it preferentially detects leukoplakia and may fail to spot red patches. Clinical trials demonstrated that sensitivity of VELscope in detecting malignancy and OPMD ranged from 22 % to 100 % and specificity ranged from 16 % to 100%. Most studies concluded that VELscope can help the experienced clinician to find oral precursor malignant lesions. But it couldnot differentiate between dysplasia and benign inflammatory conditions. Both devices are simple, non-invasive test of the oral mucosa but are suited for clinicians with sufficient experience and training. More clinical trials in future should be conducted to establish optical imaging as an efficacious adjunct tool in early diagnosis of OSCC and OPMD.

  9. Alternative SNP detection platforms, HRM and biosensors, for varietal identification in Vitis vinifera L. using F3H and LDOX genes.

    Science.gov (United States)

    Gomes, Sónia; Castro, Cláudia; Barrias, Sara; Pereira, Leonor; Jorge, Pedro; Fernandes, José R; Martins-Lopes, Paula

    2018-04-11

    The wine sector requires quick and reliable methods for Vitis vinifera L. varietal identification. The number of V. vinifera varieties is estimated in about 5,000 worldwide. Single Nucleotide Polymorphisms (SNPs) represent the most basic and abundant form of genetic sequence variation, being adequate for varietal discrimination. The aim of this work was to develop DNA-based assays suitable to detect SNP variation in V. vinifera, allowing varietal discrimination. Genotyping by sequencing allowed the detection of eleven SNPs on two genes of the anthocyanin pathway, the flavanone 3-hydroxylase (F3H, EC: 1.14.11.9), and the leucoanthocyanidin dioxygenase (LDOX, EC 1.14.11.19; synonym anthocyanidin synthase, ANS) in twenty V. vinifera varieties. Three High Resolution Melting (HRM) assays were designed based on the sequencing information, discriminating five of the 20 varieties: Alicante Bouschet, Donzelinho Tinto, Merlot, Moscatel Galego and Tinta Roriz. Sanger sequencing of the HRM assay products confirmed the HRM profiles. Three probes, with different lengths and sequences, were used as bio-recognition elements in an optical biosensor platform based on a long period grating (LPG) fiber optic sensor. The label free platform detected a difference of a single SNP using genomic DNA samples. The two different platforms were successfully applied for grapevine varietal identification.

  10. Chemical warfare agents identification by thermal neutron detection

    International Nuclear Information System (INIS)

    Liu Boxue; Ai Xianyun; Tan Daoyuan; Zhang Dianqin

    2000-01-01

    The hydrogen concentration determination by thermal neutron detection is a non-destructive, fast and effective method to identify chemical warfare agents and TNT that contain different hydrogen fraction. When an isotropic neutron source is used to irradiate chemical ammunition, hydrogen atoms of the agent inside shell act as a moderator and slow down neutrons. The number of induced thermal neutrons depends mainly upon hydrogen content of the agent. Therefore measurement of thermal neutron influence can be used to determine hydrogen atom concentration, thereby to determine the chemical warfare agents. Under a certain geometry three calibration curves of count rate against hydrogen concentration were measured. According to the calibration curves, response of a chemical agent or TNT could be calculated. Differences of count rate among chemical agents and TNT for each kind of shells is greater than five times of standard deviations of count rate for any agent, so chemical agents or TNT could be identified correctly. Meanwhile, blast tube or liquid level of chemical warfare agent could affect the response of thermal neutron count rate, and thereby the result of identification. (author)

  11. Identification of Polish cochineal (Porphyrophora polonica L.) in historical textiles by high-performance liquid chromatography coupled with spectrophotometric and tandem mass spectrometric detection.

    Science.gov (United States)

    Lech, Katarzyna; Jarosz, Maciej

    2016-05-01

    The present work reports a method for identification of Polish cochineal (Porphyrophora polonica L.) in historical fabrics by the use of high-performance liquid chromatography coupled with diode array and tandem mass spectrometric detection with electrospray ionization (HPLC-DAD-ESI MS/MS). This hyphened technique allows detection and identification of 16 new minor colorants present in the discussed scale insect (including two previously observed by Wouters and Verhecken (Ann Soc Entomol Fr. 1989;25:393-410), but specified only as compounds of unknown structures) that do not occur (e.g., in American cochineal). The MS/MS experiments, complemented with UV-VIS data, enable identification of mono- and di-, C- and O-hexosides of kermesic and flavokermesic acids or their derivatives. The present paper introduces a fingerprint of color compounds present in Polish cochineal and defines them, particularly pp6 (ppI, O-hexoside of flavokermesic acid), as its markers allow distinguishing of Polish-cochineal reds from the American ones. Usefulness of the selected set of markers for identification of Polish cochineal has been demonstrated in the examination of textiles from the collection of the National Museum in Warsaw using the multiple reaction monitoring (MRM) method, originally elaborated on the basis of this study.

  12. Sensor device and methods for using same

    Science.gov (United States)

    Rothgeb, Timothy Michael; Gansle, Kristina Marie Rohal; Joyce, Jonathan Livingston; Jordan, James Madison; Rohwer, Tedd Addison; Lockhart, Randal Ray; Smith, Christopher Lawrence; Trinh, Toan; Cipollone, Mark Gary

    2005-10-25

    A sensor device and method of employment is provided. More specifically, a sensor device adapted to detect, identify and/or measure a chemical and/or physical characteristic upon placement of the device into an environment, especially a liquid medium for which monitoring is sought is provided.

  13. Low-Power Implantable Device for Onset Detection and Subsequent Treatment of Epileptic Seizures: A Review

    Directory of Open Access Journals (Sweden)

    Muhammad Tariqus Salam

    2010-01-01

    Full Text Available Over the past few years, there has been growing interest in neuro-responsive intracerebral local treatments of seizures, such as focal drug delivery, focal cooling, or electrical stimulation. This mode of treatment requires an effective intracerebral electroencephalographic acquisition system, seizure detector, brain stimulator, and wireless system that consume ultra-low power. This review focuses on alternative brain stimulation treatments for medically intractable epilepsy patients. We mainly discuss clinical studies of long-term responsive stimulation and suggest safer optimized therapeutic options for epilepsy. Finally, we conclude our study with the proposed low-power, implantable fully integrated device that automatically detects low-voltage fast activity ictal onsets and triggers focal treatment to disrupt seizure progression. The detection performance was verified using intracerebral electroencephalographic recordings from two patients with epilepsy. Further experimental validation of this prototype is underway.

  14. Effects of Active and Passive Hearing Protection Devices on Sound Source Localization, Speech Recognition, and Tone Detection.

    Directory of Open Access Journals (Sweden)

    Andrew D Brown

    Full Text Available Hearing protection devices (HPDs such as earplugs offer to mitigate noise exposure and reduce the incidence of hearing loss among persons frequently exposed to intense sound. However, distortions of spatial acoustic information and reduced audibility of low-intensity sounds caused by many existing HPDs can make their use untenable in high-risk (e.g., military or law enforcement environments where auditory situational awareness is imperative. Here we assessed (1 sound source localization accuracy using a head-turning paradigm, (2 speech-in-noise recognition using a modified version of the QuickSIN test, and (3 tone detection thresholds using a two-alternative forced-choice task. Subjects were 10 young normal-hearing males. Four different HPDs were tested (two active, two passive, including two new and previously untested devices. Relative to unoccluded (control performance, all tested HPDs significantly degraded performance across tasks, although one active HPD slightly improved high-frequency tone detection thresholds and did not degrade speech recognition. Behavioral data were examined with respect to head-related transfer functions measured using a binaural manikin with and without tested HPDs in place. Data reinforce previous reports that HPDs significantly compromise a variety of auditory perceptual facilities, particularly sound localization due to distortions of high-frequency spectral cues that are important for the avoidance of front-back confusions.

  15. Reactor control device

    International Nuclear Information System (INIS)

    Fukami, Haruo; Morimoto, Yoshinori.

    1981-01-01

    Purpose: To operate a reactor always with safety operation while eliminating the danger of tripping. Constitution: In a reactor control device adapted to detect the process variants of a reactor, control a control rod drive controlling system based on the detected signal to thereby control the driving the control rods, control the reactor power and control the electric power generated from an electric generator by the output from the reactor, detection means is provided for the detection of the electric power from said electric generator, and a compensation device is provided for outputting control rod driving compensation signals to the control rod driving controlling system in accordance with the amount of variation in the detected value. (Seki, T.)

  16. Accuracy of point-of-care serum creatinine devices for detecting patients at risk of contrast-induced nephropathy: a critical overview.

    Science.gov (United States)

    Martínez Lomakin, Felipe; Tobar, Catalina

    2014-12-01

    Contrast-induced nephropathy (CIN) is a common event in hospitals, with reported incidences ranging from 1 to 30%. Patients with underlying kidney disease have an increased risk of developing CIN. Point-of-care (POC) creatinine devices are handheld devices capable of providing quantitative data on a patient's kidney function that could be useful in stratifying preventive measures. This overview aims to synthesize the current evidence on diagnostic accuracy and clinical utility of POC creatinine devices in detecting patients at risk of CIN. Five databases were searched for diagnostic accuracy studies or clinical trials that evaluated the usefulness of POC devices in detecting patients at risk of CIN. Selected articles were critically appraised to assess their individual risk of bias by the use of standard criteria; 13 studies were found that addressed the diagnostic accuracy or clinical utility of POC creatinine devices. Most studies incurred a moderate to high risk of bias. Overall concordance between POC devices and reference standards (clinical laboratory procedures) was found to be moderate, with 95% limits of agreement often lying between -35.4 and +35.4 µmol/L (-0.4 and +0.4 mg/dL). Concordance was shown to decrease with worsening kidney function. Data on the clinical utility of these devices were limited, but a significant reduction in time to diagnosis was reported in two studies. Overall, POC creatinine devices showed a moderate concordance with standard clinical laboratory creatinine measurements. Several biases could have induced optimism in these estimations. Results obtained from these devices may be unreliable in cases of severe kidney failure. Randomized trials are needed to address the clinical utility of these devices.

  17. A PCR detection method for rapid identification of Melissococcus pluton in honeybee larvae.

    Science.gov (United States)

    Govan, V A; Brözel, V; Allsopp, M H; Davison, S

    1998-05-01

    Melissococcus pluton is the causative agent of European foulbrood, a disease of honeybee larvae. This bacterium is particularly difficult to isolate because of its stringent growth requirements and competition from other bacteria. PCR was used selectively to amplify specific rRNA gene sequences of M. pluton from pure culture, from crude cell lysates, and directly from infected bee larvae. The PCR primers were designed from M. pluton 16S rRNA sequence data. The PCR products were visualized by agarose gel electrophoresis and confirmed as originating from M. pluton by sequencing in both directions. Detection was highly specific, and the probes did not hybridize with DNA from other bacterial species tested. This method enabled the rapid and specific detection and identification of M. pluton from pure cultures and infected bee larvae.

  18. Rapid Detection and Identification of Human Hookworm Infections through High Resolution Melting (HRM) Analysis

    Science.gov (United States)

    Ngui, Romano; Lim, Yvonne A. L.; Chua, Kek Heng

    2012-01-01

    Background Hookworm infections are still endemic in low and middle income tropical countries with greater impact on the socioeconomic and public health of the bottom billion of the world's poorest people. In this study, a real-time polymerase chain reaction (PCR) coupled with high resolution melting-curve (HRM) analysis was evaluated for an accurate, rapid and sensitive tool for species identification focusing on the five human hookworm species. Methods Real-time PCR coupled with HRM analysis targeting the second internal transcribed spacer (ITS-2) of nuclear ribosomal DNA as the genetic marker was used to identify and distinguish hookworm species in human samples. Unique and distinct characteristics of HRM patterns were produced for each of the five hookworm species. The melting curves were characterized by peaks of 79.24±0.05°C and 83.00±0.04°C for Necator americanus, 79.12±0.10°C for Ancylostoma duodenale, 79.40±0.10°C for Ancylostoma ceylanicum, 79.63±0.05°C for Ancylostoma caninum and 79.70±0.14°C for Ancylostoma braziliense. An evaluation of the method's sensitivity and specificity revealed that this assay was able to detect as low as 0.01 ng/µl hookworm DNA and amplification was only recorded for hookworm positive samples. Conclusion The HRM assay developed in this study is a rapid and straightforward method for the diagnosis, identification and discrimination of five human hookworms. This assay is simple compared to other probe-based genotyping methods as it does not require multiplexing, DNA sequencing or post-PCR processing. Therefore, this method offers a new alternative for rapid detection of human hookworm species. PMID:22844538

  19. Rapid detection and identification of human hookworm infections through high resolution melting (HRM analysis.

    Directory of Open Access Journals (Sweden)

    Romano Ngui

    Full Text Available BACKGROUND: Hookworm infections are still endemic in low and middle income tropical countries with greater impact on the socioeconomic and public health of the bottom billion of the world's poorest people. In this study, a real-time polymerase chain reaction (PCR coupled with high resolution melting-curve (HRM analysis was evaluated for an accurate, rapid and sensitive tool for species identification focusing on the five human hookworm species. METHODS: Real-time PCR coupled with HRM analysis targeting the second internal transcribed spacer (ITS-2 of nuclear ribosomal DNA as the genetic marker was used to identify and distinguish hookworm species in human samples. Unique and distinct characteristics of HRM patterns were produced for each of the five hookworm species. The melting curves were characterized by peaks of 79.24±0.05°C and 83.00±0.04°C for Necator americanus, 79.12±0.10°C for Ancylostoma duodenale, 79.40±0.10°C for Ancylostoma ceylanicum, 79.63±0.05°C for Ancylostoma caninum and 79.70±0.14°C for Ancylostoma braziliense. An evaluation of the method's sensitivity and specificity revealed that this assay was able to detect as low as 0.01 ng/µl hookworm DNA and amplification was only recorded for hookworm positive samples. CONCLUSION: The HRM assay developed in this study is a rapid and straightforward method for the diagnosis, identification and discrimination of five human hookworms. This assay is simple compared to other probe-based genotyping methods as it does not require multiplexing, DNA sequencing or post-PCR processing. Therefore, this method offers a new alternative for rapid detection of human hookworm species.

  20. Coolant leakage detection device

    International Nuclear Information System (INIS)

    Ito, Takao.

    1983-01-01

    Purpose: To surely detect the coolant leakage at a time when the leakage amount is still low in the intra-reactor inlet pipeway of FBR type reactor. Constitution: Outside of the intra-reactor inlet piping for introducing coolants at low temperature into a reactor core, an outer closure pipe is furnished. The upper end of the outer closure pipe opens above the liquid level of the coolants in the reactor, and a thermocouple is inserted to the opening of the upper end. In such a structure, if the coolants in the in-reactor piping should leak to the outer closure pipe, coolants over-flows from the opening thereof, at which the thermocouple detects the temperature of the coolants at a low temperature, thereby enabling to detect the leakage of the coolants at a time when it is still low. (Kamimura, M.)

  1. Improvements to a neutral radiation detection and position sensitive process and devices

    International Nuclear Information System (INIS)

    Charpak, Georges; Nguyen, N.H.; Policarpo, Armando.

    1977-01-01

    This invention aims to provide a neutral radiation position sensitive process and device providing a spatial radiation satisfactory for most medical applications and an energy radiation that cannot be reached by gas detectors based on proportional counters or by scintillation counters. Only solid state detectors can compete with respect to energy resolution. The detector described enables large areas to be covered which cannot be reached at accessible costs by solid state detectors. With this aim in view, the invention suggests an incident neutral radiation and position sensitive process, particularly soft gamma and X radiations, whereby photoelectrons are made to form by incident radiation action on gas atoms contained in an enclosure. By means of an electric field, the electrons are diverted towards a space undergoing an electric field high enough in value to create photons by exciting gas atoms and returning them to the de-excited state. The photons are collected, through a transparent window, on a layer of a material for converting such photons into scintillations in the near or visible UV spectrum and the barycentre of the scintillations is positioned on the layer, for instance by photomultipliers or ionization detectors. According to another aspect of the invention, it suggests a detection and position sensitive device comprising (generally downstream of a collimator with a grid of inlet holes) a leak tight containment fitted with an inlet window transparent to incident radiations, filled with a gas producing electrons by interaction with the incident radiation, and fitted with electrodes for generating an electric field to divert the electrons to a space for creating secondary photons [fr

  2. Intrinsic fluorescence for cervical precancer detection using polarized light based in-house fabricated portable device

    Science.gov (United States)

    Meena, Bharat Lal; Singh, Pankaj; Sah, Amar Nath; Pandey, Kiran; Agarwal, Asha; Pantola, Chayanika; Pradhan, Asima

    2018-01-01

    An in-house fabricated portable device has been tested to detect cervical precancer through the intrinsic fluorescence from human cervix of the whole uterus in a clinical setting. A previously validated technique based on simultaneously acquired polarized fluorescence and polarized elastic scattering spectra from a turbid medium is used to extract the intrinsic fluorescence. Using a diode laser at 405 nm, intrinsic fluorescence of flavin adenine dinucleotide, which is the dominant fluorophore and other contributing fluorophores in the epithelium of cervical tissue, has been extracted. Different grades of cervical precancer (cervical intraepithelial neoplasia; CIN) have been discriminated using principal component analysis-based Mahalanobis distance and linear discriminant analysis. Normal, CIN I and CIN II samples have been discriminated from one another with high sensitivity and specificity at 95% confidence level. This ex vivo study with cervix of whole uterus samples immediately after hysterectomy in a clinical environment indicates that the in-house fabricated portable device has the potential to be used as a screening tool for in vivo precancer detection using intrinsic fluorescence.

  3. Microbiological method for radiation sterilization (I). General knowledge and handling technique for bacterial identification

    International Nuclear Information System (INIS)

    Koshikawa, Tomihiko

    2004-01-01

    The part I in this title series describes the basic knowledge and technique for identification of bacteria in the radiation sterilization of medical devices, where the radiation dose can be decided from the number and radio-resistance of the bioburden (bacteria on the device). Four essential, actual technologies for identification are described: isolation and storage of bacteria; decision of bacterial natures, involving 3 Gram staining methods, morphology by microscopy and/or phase-contrast microscopy, spore-forming bacteria, and size measurement by micrometry; Other test items for identification of genus, involving motility, oxygen demand, catalase, oxidase, acid production from glucose, and OF (oxidation or fermentation for glucose degradation) test; and colony observation. Media, identification kits and record forms for these are presented. (N.I.)

  4. Detection of Helminth Eggs and Identification of Hookworm Species in Stray Cats, Dogs and Soil from Klang Valley, Malaysia.

    Directory of Open Access Journals (Sweden)

    Sandee Tun

    Full Text Available The present study was conducted to determine the prevalence of helminth eggs excreted in the faeces of stray cats, dogs and in soil samples. A total of 505 fresh samples of faeces (from 227 dogs and 152 cats and soil were collected. The egg stage was detected via microscopy after the application of formalin-ether concentration technique. Genomic DNA was extracted from the samples containing hookworm eggs and used for further identification to the species level using real-time polymerase chain reaction coupled with high resolution melting analysis. Microscopic observation showed that the overall prevalence of helminth eggs among stray cats and dogs was 75.7% (95% CI = 71.2%-79.9%, in which 87.7% of dogs and 57.9% of cats were infected with at least one parasite genus. Five genera of heliminth eggs were detected in the faecal samples, including hookworms (46.4%, Toxocara (11.1%, Trichuris (8.4%, Spirometra (7.4% and Ascaris (2.4%. The prevalence of helminth infections among stray dogs was significantly higher than that among stray cats (p < 0.001. Only three genera of helminths were detected in soil samples with the prevalence of 23% (95% CI = 15.1%-31%, consisting of hookworms (16.6%, Ascaris (4% and Toxocara (2.4%. The molecular identification of hookworm species revealed that Ancylostoma ceylanicum was dominant in both faecal and soil samples. The dog hookworm, Ancylostoma caninum, was also detected among cats, which is the first such occurrence reported in Malaysia till date. This finding indicated that there was a cross-infection of A. caninum between stray cats and dogs because of their coexistent within human communities. Taken together, these data suggest the potential role of stray cats and dogs as being the main sources of environmental contamination as well as for human infections.

  5. The signature-based radiation-scanning approach to standoff detection of improvised explosive devices

    International Nuclear Information System (INIS)

    Brewer, R.L.; Dunn, W.L.; Heider, S.; Matthew, C.; Yang, X.

    2012-01-01

    The signature-based radiation-scanning technique for detection of improvised explosive devices is described. The technique seeks to detect nitrogen-rich chemical explosives present in a target. The technology compares a set of “signatures” obtained from a test target to a collection of “templates”, sets of signatures for a target that contain an explosive in a specific configuration. Interrogation of nitrogen-rich fertilizer samples, which serve as surrogates for explosives, is shown experimentally to be able to discriminate samples of 3.8 L and larger. - Highlights: ► Signature-based radiation-scanning techniques applied to detection of explosives. ► Nitrogen-rich fertilizer samples served as surrogate explosive samples. ► Signatures of a target compared to collections of templates of surrogate explosives. ► Figure-of-merit determined for neutron and neutron-induced gamma-ray signatures. ► Discrimination of surrogate explosive from inert samples of 3.8 L and larger.

  6. Apparatus, System and Method for Fast Detection of Genetic Information by PCR in an Interchangeable Chip

    KAUST Repository

    Wen, Weijia

    2011-03-03

    A polymerase chain reaction (PCR) device for fast amplification and detection of DNA includes an interchangeable PCR chamber, a temperature control component, and an optical detection system. The DNA amplification is performed on an interchangeable chip with volumes as small as 1.25 µl, while the heating and cooling rate may be as fast as 12.7 °C/second ensuring that the total time needed of only 25 minutes to complete the 35 cycle PCR amplification. The PCR may be performed according to a two-temperature approach for denaturing and annealing (Td and Ta) of DNA with the PCR chip, with which the amplification of male-specific SRY gene marker by utilizing raw saliva may be achieved. The genetic identification may be in-situ detected after PCR by the optical detection system.

  7. 76 FR 69034 - Microbiology Devices; Classification of In Vitro Diagnostic Device for Yersinia Species Detection

    Science.gov (United States)

    2011-11-07

    ... Drug Administration 21 CFR Part 866 Microbiology Devices; Classification of In Vitro Diagnostic Device... CFR Part 866 [Docket No. FDA-2011-N-0729] Microbiology Devices; Classification of In Vitro Diagnostic... of the Microbiology Devices Advisory Panel (the panel). FDA is publishing in this document the...

  8. 76 FR 28689 - Microbiology Devices; Classification of In Vitro Diagnostic Device for Bacillus Species Detection

    Science.gov (United States)

    2011-05-18

    .... FDA-2011-N-0103] Microbiology Devices; Classification of In Vitro Diagnostic Device for Bacillus... of the Microbiology Devices Advisory Panel (the Panel). In addition, the proposed rule would... in the Federal Register. 1. Transcript of the FDA Microbiology Devices Panel meeting, March 7, 2002...

  9. Incipient fault detection and identification in process systems using accelerating neural network learning

    International Nuclear Information System (INIS)

    Parlos, A.G.; Muthusami, J.; Atiya, A.F.

    1994-01-01

    The objective of this paper is to present the development and numerical testing of a robust fault detection and identification (FDI) system using artificial neural networks (ANNs), for incipient (slowly developing) faults occurring in process systems. The challenge in using ANNs in FDI systems arises because of one's desire to detect faults of varying severity, faults from noisy sensors, and multiple simultaneous faults. To address these issues, it becomes essential to have a learning algorithm that ensures quick convergence to a high level of accuracy. A recently developed accelerated learning algorithm, namely a form of an adaptive back propagation (ABP) algorithm, is used for this purpose. The ABP algorithm is used for the development of an FDI system for a process composed of a direct current motor, a centrifugal pump, and the associated piping system. Simulation studies indicate that the FDI system has significantly high sensitivity to incipient fault severity, while exhibiting insensitivity to sensor noise. For multiple simultaneous faults, the FDI system detects the fault with the predominant signature. The major limitation of the developed FDI system is encountered when it is subjected to simultaneous faults with similar signatures. During such faults, the inherent limitation of pattern-recognition-based FDI methods becomes apparent. Thus, alternate, more sophisticated FDI methods become necessary to address such problems. Even though the effectiveness of pattern-recognition-based FDI methods using ANNs has been demonstrated, further testing using real-world data is necessary

  10. Application of Devices and Systems Designed for Power Quality Monitoring and Assessment

    Directory of Open Access Journals (Sweden)

    Wiesław Gil

    2014-03-01

    Full Text Available The paper presents the problems associated with increasing demands on the equipment and systems for power quality assessment (PQ, installed at power substations. Difficulties are signaled due to current lack of standards defining the test methodology of measuring devices. The necessary device properties and the structure of a large system operated in real time and designed to assess the PQ are discussed. The usefulness of multi-channel analyzers featuring the identification and registration of transients is pointed out. The desirability of synchrophasor assessment implementation and device integration by standard PN-EN 61850 with other SAS devices is also justified.

  11. The Performance of the Four Anaerobic Blood Culture Bottles BacT/ALERT-FN, -FN Plus, BACTEC-Plus and -Lytic in Detection of Anaerobic Bacteria and Identification by Direct MALDI-TOF MS.

    Directory of Open Access Journals (Sweden)

    Mohammed Almuhayawi

    Full Text Available Detection and identification of anaerobic bacteria in blood cultures (BC is a well-recognized challenge in clinical microbiology. We studied 100 clinical anaerobic BC isolates to evaluate the performance of BacT/ALERT-FN, -FN Plus (BioMérieux, BACTEC-Plus and -Lytic (Becton Dickinson BioSciences BC bottles in detection and time to detection (TTD of anaerobic bacteria. BACTEC Lytic had higher detection rate (94/100, 94% than BacT/ALERT FN Plus (80/100, 80% (p<0.01 in the studied material. There was no significant difference in detection of anaerobic bacteria among the remaining bottle types. The 67 anaerobic bacteria that signalled positive in all four bottle types were analyzed to compare the time to detection (TTD and isolates were directly identified by MALDI-TOF MS. There was a significant difference in TTD among the four bottle types (p<0.0001. The shortest median TTD was 18 h in BACTEC Lytic followed by BacT/ALERT FN (23.5 h, BACTEC Plus (27 h and finally BacT/ALERT FN Plus (38 h bottles. In contrast, MALDI-TOF MS performed similarly in all bottle types with accurate identification in 51/67 (76% BacT/ALERT FN, 51/67 (76% BacT/ALERT FN Plus, 53/67 (79% BACTEC Plus and 50/67 (75% BACTEC Lytic bottles. In conclusion, BACTEC Lytic bottles have significantly better detection rates and shorter TTD compared to the three other bottle types. The anaerobic BC bottles are equally suitable for direct MALDI-TOF MS for rapid and reliable identification of common anaerobic bacteria. Further clinical studies are warranted to investigate the performance of anaerobic BC bottles in detection of anaerobic bacteria and identification by direct MALDI-TOF MS.

  12. Comments on particle identification at the B factory

    International Nuclear Information System (INIS)

    Ratcliff, B.N.

    1992-01-01

    The importance of particle identification at an asymmetric B Factory is discussed, and the general status of a number of particle identification technologies which might be included in B Factory detectors is briefly reviewed. It is generally agreed that high quality hadronic particle identification is fundamental to the central mission of understanding CP violation at the B Factory, but there is as yet no clear open-quotes consensusclose quotes solution for such a detector. In a sense, this lack of a particle identification solution is a matter of definition. There is, in fact, a perfectly reasonable, open-quotes conventional technologyclose quotes, particle identification system which makes use of a large tracking chamber with excellent (i.e., relativistic rise quality) dE/dx surrounded by a good TOF with a rather long flight path. The chamber must be rather large (around 2 meters in outer radius) and perhaps high pressure as well, but similar devices are rather well understood and it would appear to be possible to meet the particle identification performance required at B Factory momenta. This solution has not been embraced by any of the detector groups, however, because of the effect it has on the electromagnetic calorimetry. open-quotes Everyoneclose quotes wants high quality calorimetry (such as can be provided by CsI crystals), but such devices cost a great deal per unit volume, and the cost scales roughly like the inner radius squared. Moreover, no one wants to see the high quality (expensive) calorimetry compromised by excessive mass in front. Thus, the essence of the particle identification problem is that there is no approximately massless, very thin particle identification device known with adequate performance. Of course, it might equally well be said that there is no high quality calorimeter known which is sufficiently cost-effective to be placed outside an appropriately sized tracking plus particle identification system

  13. Correlation dynamics and enhanced signals for the identification of serial biomolecules and DNA bases

    International Nuclear Information System (INIS)

    Ahmed, Towfiq; Haraldsen, Jason T; Balatsky, Alexander V; Rehr, John J; Di Ventra, Massimiliano; Schuller, Ivan

    2014-01-01

    Nanopore-based sequencing has demonstrated a significant potential for the development of fast, accurate, and cost-efficient fingerprinting techniques for next generation molecular detection and sequencing. We propose a specific multilayered graphene-based nanopore device architecture for the recognition of single biomolecules. Molecular detection and analysis can be accomplished through the detection of transverse currents as the molecule or DNA base translocates through the nanopore. To increase the overall signal-to-noise ratio and the accuracy, we implement a new ‘multi-point cross-correlation’ technique for identification of DNA bases or other molecules on the single molecular level. We demonstrate that the cross-correlations between each nanopore will greatly enhance the transverse current signal for each molecule. We implement first-principles transport calculations for DNA bases surveyed across a multilayered graphene nanopore system to illustrate the advantages of the proposed geometry. A time-series analysis of the cross-correlation functions illustrates the potential of this method for enhancing the signal-to-noise ratio. This work constitutes a significant step forward in facilitating fingerprinting of single biomolecules using solid state technology. (paper)

  14. Correlation dynamics and enhanced signals for the identification of serial biomolecules and DNA bases

    Science.gov (United States)

    Ahmed, Towfiq; Haraldsen, Jason T.; Rehr, John J.; Di Ventra, Massimiliano; Schuller, Ivan; Balatsky, Alexander V.

    2014-03-01

    Nanopore-based sequencing has demonstrated a significant potential for the development of fast, accurate, and cost-efficient fingerprinting techniques for next generation molecular detection and sequencing. We propose a specific multilayered graphene-based nanopore device architecture for the recognition of single biomolecules. Molecular detection and analysis can be accomplished through the detection of transverse currents as the molecule or DNA base translocates through the nanopore. To increase the overall signal-to-noise ratio and the accuracy, we implement a new ‘multi-point cross-correlation’ technique for identification of DNA bases or other molecules on the single molecular level. We demonstrate that the cross-correlations between each nanopore will greatly enhance the transverse current signal for each molecule. We implement first-principles transport calculations for DNA bases surveyed across a multilayered graphene nanopore system to illustrate the advantages of the proposed geometry. A time-series analysis of the cross-correlation functions illustrates the potential of this method for enhancing the signal-to-noise ratio. This work constitutes a significant step forward in facilitating fingerprinting of single biomolecules using solid state technology.

  15. Neutron measuring device

    International Nuclear Information System (INIS)

    Hatayama, Akiyoshi; Seki, Eiji; Kita, Yoshio; Nishitani, Takeo.

    1993-01-01

    The device of the present invention concerns measurement for neutrons in a tokamak type thermonuclear device and it can measure total amount of generated neutrons accurately throughout the operation period even if an error is caused in counted values by plasma disruption. That is, the device comprises (1) a means for detecting presence or absence of occurrence of plasma disruption and the time for the initiation of the occurrence, (2) a first data processing means for processing detection signals, (3) a means for detecting neutrons generated in plasmas and (4) a second data processing means for calculating integrated values for the number of neutrons generated from the start to the completion of electric discharge when no disruption occurs and calculating integrated values for the number of generated neutrons from the start of electric discharge to the time at the initiation of occurrence of the disruption when disruption is present. In the thus constituted device, even if an error is caused by frequent occurrence of plasma disruption, total time integrated amount of neutrons generated in the plasmas can be measured accurately. (I.S.)

  16. Remote spectroscopic identification of bloodstains

    NARCIS (Netherlands)

    Bremmer, Rolf H.; Edelman, Gerda; Vegter, Tessa Dijn; Bijvoets, Ted; Aalders, Maurice C. G.

    2011-01-01

    Blood detection and identification at crime scenes are crucial for harvesting forensic evidence. Unfortunately, most tests for the identification of blood are destructive and time consuming. We present a fast and nondestructive identification test for blood, using noncontact reflectance

  17. 78 FR 18988 - Establishing the Performance Characteristics of In Vitro Diagnostic Devices for the Detection of...

    Science.gov (United States)

    2013-03-28

    ... either electronic or written comments on this guidance at any time. General comments on Agency guidance... INFORMATION section for information on electronic access to the guidance. Submit electronic comments on the... diagnostic devices for the detection of antibodies to B. burgdorferi in human serum, plasma, and blood. These...

  18. Opto-Electromechanical Devices for Low-Noise Detection of Radio Waves

    DEFF Research Database (Denmark)

    Bagci, Tolga

    factors. For example, a hybrid system like this, would enable the use of well-established shot-noise limited optical sensing technologies for detecting weak radio-frequency (rf) signals, rf-to-optical photon conversion and transmission of information in low-loss fiber-optic links over long distances......There is currently an increasing interest in developing hybrid devices that unite the desirable features of different systems. Opto-electromechanics has emerged as one of these promising hybrid fields, where the functionality of conventional electrical circuits can be combined with the salient...... features of optical systems for various technological and sensing applications. Nanomechanical resonators stand as promising candidates in terms of linking the two systems, primarily thanks to their versatility in coupling to various physical systems, together with their excellent mechanical quality...

  19. Snapshot spectral and polarimetric imaging; target identification with multispectral video

    Science.gov (United States)

    Bartlett, Brent D.; Rodriguez, Mikel D.

    2013-05-01

    As the number of pixels continue to grow in consumer and scientific imaging devices, it has become feasible to collect the incident light field. In this paper, an imaging device developed around light field imaging is used to collect multispectral and polarimetric imagery in a snapshot fashion. The sensor is described and a video data set is shown highlighting the advantage of snapshot spectral imaging. Several novel computer vision approaches are applied to the video cubes to perform scene characterization and target identification. It is shown how the addition of spectral and polarimetric data to the video stream allows for multi-target identification and tracking not possible with traditional RGB video collection.

  20. Radioactive gas storage device

    International Nuclear Information System (INIS)

    Sano, Yuji.

    1988-01-01

    Purpose: To easily and reliably detect the consumption of a sputtered cathode in a radioactive gas storage device using ion injection method. Constitution: Inert gases are sealed to the inside of a cathode. As the device is operated, the cathode is consumed and, if it is scraped to some extent, inert gases in the cathode gases are blown out to increase the inner pressure of the device. The pressure elevation is detected by a pressure detector connected with a gas introduction pipe or discharge pipe. Further, since the discharge current in the inside is increased along with the elevation of the pressure, it is possible to detect the increase of the electrical current. In this way, the consumption of the cathode can be recognized by detecting the elevation in the pressure or increase in the current. (Ikeda, J.)

  1. System Identification of a Heaving Point Absorber: Design of Experiment and Device Modeling

    Directory of Open Access Journals (Sweden)

    Giorgio Bacelli

    2017-04-01

    Full Text Available Empirically based modeling is an essential aspect of design for a wave energy converter. Empirically based models are used in structural, mechanical and control design processes, as well as for performance prediction. Both the design of experiments and methods used in system identification have a strong impact on the quality of the resulting model. This study considers the system identification and model validation process based on data collected from a wave tank test of a model-scale wave energy converter. Experimental design and data processing techniques based on general system identification procedures are discussed and compared with the practices often followed for wave tank testing. The general system identification processes are shown to have a number of advantages, including an increased signal-to-noise ratio, reduced experimental time and higher frequency resolution. The experimental wave tank data is used to produce multiple models using different formulations to represent the dynamics of the wave energy converter. These models are validated and their performance is compared against one another. While most models of wave energy converters use a formulation with surface elevation as an input, this study shows that a model using a hull pressure measurement to incorporate the wave excitation phenomenon has better accuracy.

  2. Enhanced detection method for corneal protein identification using shotgun proteomics

    Directory of Open Access Journals (Sweden)

    Schlager John J

    2009-06-01

    Full Text Available Abstract Background The cornea is a specialized transparent connective tissue responsible for the majority of light refraction and image focus for the retina. There are three main layers of the cornea: the epithelium that is exposed and acts as a protective barrier for the eye, the center stroma consisting of parallel collagen fibrils that refract light, and the endothelium that is responsible for hydration of the cornea from the aqueous humor. Normal cornea is an immunologically privileged tissue devoid of blood vessels, but injury can produce a loss of these conditions causing invasion of other processes that degrade the homeostatic properties resulting in a decrease in the amount of light refracted onto the retina. Determining a measure and drift of phenotypic cornea state from normal to an injured or diseased state requires knowledge of the existing protein signature within the tissue. In the study of corneal proteins, proteomics procedures have typically involved the pulverization of the entire cornea prior to analysis. Separation of the epithelium and endothelium from the core stroma and performing separate shotgun proteomics using liquid chromatography/mass spectrometry results in identification of many more proteins than previously employed methods using complete pulverized cornea. Results Rabbit corneas were purchased, the epithelium and endothelium regions were removed, proteins processed and separately analyzed using liquid chromatography/mass spectrometry. Proteins identified from separate layers were compared against results from complete corneal samples. Protein digests were separated using a six hour liquid chromatographic gradient and ion-trap mass spectrometry used for detection of eluted peptide fractions. The SEQUEST database search results were filtered to allow only proteins with match probabilities of equal or better than 10-3 and peptides with a probability of 10-2 or less with at least two unique peptides isolated within

  3. Peptide Functionalized Gold Nanorods for the Sensitive Detection of a Cardiac Biomarker Using Plasmonic Paper Devices (Postprint)

    Science.gov (United States)

    2015-11-10

    Albumin to saturate the non-specific binding sites on the paper substrate prior to troponin exposure. For testing the biosensor, troponin of various...AFRL-RX-WP-JA-2016-0191 PEPTIDE FUNCTIONALIZED GOLD NANORODS FOR THE SENSITIVE DETECTION OF A CARDIAC BIOMARKER USING PLASMONIC PAPER ...SENSITIVE DETECTION OF A CARDIAC BIOMARKER USING PLASMONIC PAPER DEVICES (POSTPRINT) 5a. CONTRACT NUMBER FA8650-15-D-5405-0001 5b. GRANT NUMBER 5c

  4. Developing nucleic acid-based electrical detection systems

    Directory of Open Access Journals (Sweden)

    Gabig-Ciminska Magdalena

    2006-03-01

    Full Text Available Abstract Development of nucleic acid-based detection systems is the main focus of many research groups and high technology companies. The enormous work done in this field is particularly due to the broad versatility and variety of these sensing devices. From optical to electrical systems, from label-dependent to label-free approaches, from single to multi-analyte and array formats, this wide range of possibilities makes the research field very diversified and competitive. New challenges and requirements for an ideal detector suitable for nucleic acid analysis include high sensitivity and high specificity protocol that can be completed in a relatively short time offering at the same time low detection limit. Moreover, systems that can be miniaturized and automated present a significant advantage over conventional technology, especially if detection is needed in the field. Electrical system technology for nucleic acid-based detection is an enabling mode for making miniaturized to micro- and nanometer scale bio-monitoring devices via the fusion of modern micro- and nanofabrication technology and molecular biotechnology. The electrical biosensors that rely on the conversion of the Watson-Crick base-pair recognition event into a useful electrical signal are advancing rapidly, and recently are receiving much attention as a valuable tool for microbial pathogen detection. Pathogens may pose a serious threat to humans, animal and plants, thus their detection and analysis is a significant element of public health. Although different conventional methods for detection of pathogenic microorganisms and their toxins exist and are currently being applied, improvements of molecular-based detection methodologies have changed these traditional detection techniques and introduced a new era of rapid, miniaturized and automated electrical chip detection technologies into pathogen identification sector. In this review some developments and current directions in

  5. 77 FR 40735 - Unique Device Identification System

    Science.gov (United States)

    2012-07-10

    ... lessons learned from these pilot activities. FDA also solicited input through public meetings; a public... used to identify devices, and no assurance that different companies are using a given term in the same... weaknesses or problems in our implementation of the UDI system and to make appropriate mid-course corrections...

  6. Easier detection of invertebrate "identification-key characters" with light of different wavelengths

    Directory of Open Access Journals (Sweden)

    Koken Marcel HM

    2011-10-01

    Full Text Available Abstract The marine α-taxonomist often encounters two problems. Firstly, the "environmental dirt" that is frequently present on the specimens and secondly the difficulty in distinguishing key-features due to the uniform colours which fixed animals often adopt. Here we show that illuminating animals with deep-blue or ultraviolet light instead of the normal white-light abrogates both difficulties; dirt disappears and important details become clearly visible. This light regime has also two other advantages. It allows easy detection of very small, normally invisible, animals (0.1 μm range. And as these light wavelengths can induce fluorescence, new identification markers may be discovered by this approach.

  7. Exploring a New Security Framework for Remote Patient Monitoring Devices

    Directory of Open Access Journals (Sweden)

    Brian Ondiege

    2017-02-01

    Full Text Available Security has been an issue of contention in healthcare. The lack of familiarity and poor implementation of security in healthcare leave the patients’ data vulnerable to attackers. The main issue is assessing how we can provide security in an RPM infrastructure. The findings in literature show there is little empirical evidence on proper implementation of security. Therefore, there is an urgent need in addressing cybersecurity issues in medical devices. Through the review of relevant literature in remote patient monitoring and use of a Microsoft threat modelling tool, we identify and explore current vulnerabilities and threats in IEEE 11073 standard devices to propose a new security framework for remote patient monitoring devices. Additionally, current RPM devices have a limitation on the number of people who can share a single device, therefore, we propose the use of NFC for identification in Remote Patient Monitoring (RPM devices for multi-user environments where we have multiple people sharing a single device to reduce errors associated with incorrect user identification. We finally show how several techniques have been used to build the proposed framework.

  8. Endogenous Plasma Peptide Detection and Identification in the Rat by a Combination of Fractionation Methods and Mass Spectrometry

    Directory of Open Access Journals (Sweden)

    Fabrice Bertile

    2007-01-01

    Full Text Available Mass spectrometry-based analyses are essential tools in the field of biomarker research. However, detection and characterization of plasma low abundance and/or low molecular weight peptides is challenged by the presence of highly abundant proteins, salts and lipids. Numerous strategies have already been tested to reduce the complexity of plasma samples. The aim of this study was to enrich the low molecular weight fraction of rat plasma. To this end, we developed and compared simple protocols based on membrane filtration, solid phase extraction, and a combination of both. As assessed by UV absorbance, an albumin depletion 99% was obtained. The multistep fractionation strategy (including reverse phase HPLC allowed detection, in a reproducible manner (CV [1] 30%–35%, of more than 450 peaks below 3000 Da by MALDI-TOF/MS. A MALDI-TOF/MS-determined LOD as low as 1 fmol/μL was obtained, thus allowing nanoLC-Chip/ MS/MS identification of spiked peptides representing ∼10–6% of total proteins, by weight. Signal peptide recovery ranged between 5%–100% according to the spiked peptide considered. Tens of peptide sequence tags from endogenous plasma peptides were also obtained and high confidence identifications of low abundance fibrinopeptide A and B are reported here to show the efficiency of the protocol. It is concluded that the fractionation protocol presented would be of particular interest for future differential (high throughput analyses of the plasma low molecular weight fraction.

  9. Real-time PCR assays for detection of Brucella spp. and the identification of genotype ST27 in bottlenose dolphins (Tursiops truncatus).

    Science.gov (United States)

    Wu, Qingzhong; McFee, Wayne E; Goldstein, Tracey; Tiller, Rebekah V; Schwacke, Lori

    2014-05-01

    Rapid detection of Brucella spp. in marine mammals is challenging. Microbiologic culture is used for definitive diagnosis of brucellosis, but is time consuming, has low sensitivity and can be hazardous to laboratory personnel. Serological methods can aid in diagnosis, but may not differentiate prior exposure versus current active infection and may cross-react with unrelated Gram-negative bacteria. This study reports a real-time PCR assay for the detection of Brucella spp. and application to screen clinical samples from bottlenose dolphins stranded along the coast of South Carolina, USA. The assay was found to be 100% sensitive for the Brucella strains tested, and the limit of detection was 0.27fg of genomic DNA from Brucella ceti B1/94 per PCR volume. No amplification was detected for the non-Brucella pathogens tested. Brucella DNA was detected in 31% (55/178) of clinical samples tested. These studies indicate that the real-time PCR assay is highly sensitive and specific for the detection of Brucella spp. in bottlenose dolphins. We also developed a second real-time PCR assay for rapid identification of Brucella ST27, a genotype that is associated with human zoonotic infection. Positive results were obtained for Brucella strains which had been identified as ST27 by multilocus sequence typing. No amplification was found for other Brucella strains included in this study. ST27 was identified in 33% (18/54) of Brucella spp. DNA-positive clinical samples. To our knowledge, this is the first report on the use of a real-time PCR assay for identification of Brucella genotype ST27 in marine mammals. Copyright © 2014 Elsevier B.V. All rights reserved.

  10. Performance Assessment of the CapitalBio Mycobacterium Identification Array System for Identification of Mycobacteria

    Science.gov (United States)

    Liu, Jingbo; Yan, Zihe; Han, Min; Han, Zhijun; Jin, Lingjie; Zhao, Yanlin

    2012-01-01

    The CapitalBio Mycobacterium identification microarray system is a rapid system for the detection of Mycobacterium tuberculosis. The performance of this system was assessed with 24 reference strains, 486 Mycobacterium tuberculosis clinical isolates, and 40 clinical samples and then compared to the “gold standard” of DNA sequencing. The CapitalBio Mycobacterium identification microarray system showed highly concordant identification results of 100% and 98.4% for Mycobacterium tuberculosis complex (MTC) and nontuberculous mycobacteria (NTM), respectively. The sensitivity and specificity of the CapitalBio Mycobacterium identification array for identification of Mycobacterium tuberculosis isolates were 99.6% and 100%, respectively, for direct detection and identification of clinical samples, and the overall sensitivity was 52.5%. It was 100% for sputum, 16.7% for pleural fluid, and 10% for bronchoalveolar lavage fluid, respectively. The total assay was completed in 6 h, including DNA extraction, PCR, and hybridization. The results of this study confirm the utility of this system for the rapid identification of mycobacteria and suggest that the CapitalBio Mycobacterium identification array is a molecular diagnostic technique with high sensitivity and specificity that has the capacity to quickly identify most mycobacteria. PMID:22090408

  11. Detection device of dangerous radiation for the living beings

    International Nuclear Information System (INIS)

    Lacoste, F.

    1991-01-01

    This invention is about a portable device able to measure dose rates or doses of gamma, ultraviolet and X radiation or charged particles. This device is composed of a radiation detector, a calculator of the accumulate dose and a memory to store the data. This device has a credit card format

  12. Plant abnormality inspection device

    International Nuclear Information System (INIS)

    Takenaka, Toshio.

    1990-01-01

    The present invention concerns a plant abnormality inspection device for conducting remote or automatic patrolling inspection in a plant and, more particularly, relates to such a device as capable of detecting abnormal odors. That is, the device comprises a moving device for moving to a predetermined position in the plant, a plurality of gas sensors for different kind of gases to be inspected mounted thereon, a comparator for comparing the concentration of a gas detected by the gas sensor with the normal gas concentration at the predetermined position and a judging means for judging the absence or presence of abnormality depending on the combination of the result of the comparison and deliverying a signal if the state is abnormal. As a result, a slight amount of gas responsible to odors released upon abnormality of the plant can be detected by a plurality of gas sensors for different kinds gases to rapidly and easily find abnormal portions in the plant. (I.S.)

  13. Evaluation of Rapid Stain IDentification (RSID™ Reader System for Analysis and Documentation of RSID™ Tests

    Directory of Open Access Journals (Sweden)

    Pravatchai W. Boonlayangoor

    2013-08-01

    Full Text Available The ability to detect the presence of body fluids is a crucial first step in documenting and processing forensic evidence. The Rapid Stain IDentification (RSID™ tests for blood, saliva, semen and urine are lateral flow immunochromatographic strip tests specifically designed for forensic use. Like most lateral flow strips, the membrane components of the test are enclosed in a molded plastic cassette with a sample well and an observation window. No specialized equipment is required to use these tests or to score the results seen in the observation window; however, the utility of these tests can be enhanced if an electronic record of the test results can be obtained, preferably by a small hand-held device that could be used in the field under low light conditions. Such a device should also be able to “read” the lateral flow strips and accurately record the results of the test as either positive, i.e., the body fluid was detected, or negative, i.e., the body fluid was not detected. Here we describe the RSID™ Reader System—a ruggedized strip test reader unit that allows analysis and documentation of RSID™ lateral flow strip tests using pre-configured settings, and show that the RSID™ Reader can accurately and reproducibly report and record correct results from RSID™ blood, saliva, semen, and urine tests.

  14. Identification of radioactive sources and devices. Reference manual

    International Nuclear Information System (INIS)

    2007-01-01

    This publication is intended to be a basic guide and not a comprehensive tool kit to identify and provide detailed emergency handling instructions for radioactive sources, devices and transport containers. In addition, this publication helps to identify sources and highlight the risks they present, and provides information on appropriate action. It is a small but significant step in the international community's continuing efforts to strengthen control of radioactive sources and nuclear material, increase safety and security, and thereby make the benefits of radioactive sources ever more broadly accessible. This publication was partly funded through the Nuclear Security Fund established under the Nuclear Security Plan

  15. Rapid detection and identification of four major Schistosoma species by high-resolution melt (HRM) analysis.

    Science.gov (United States)

    Li, Juan; Zhao, Guang-Hui; Lin, RuiQing; Blair, David; Sugiyama, Hiromu; Zhu, Xing-Quan

    2015-11-01

    Schistosomiasis, caused by blood flukes belonging to several species of the genus Schistosoma, is a serious and widespread parasitic disease. Accurate and rapid differentiation of these etiological agents of animal and human schistosomiasis to species level can be difficult. We report a real-time PCR assay coupled with a high-resolution melt (HRM) assay targeting a portion of the nuclear 18S rDNA to detect, identify, and distinguish between four major blood fluke species (Schistosoma japonicum, Schistosoma mansoni, Schistosoma haematobium, and Schistosoma mekongi). Using this system, the Schistosoma spp. was accurately identified and could also be distinguished from all other trematode species with which they were compared. As little as 10(-5) ng genomic DNA from a Schistosoma sp. could be detected. This process is inexpensive, easy, and can be completed within 3 h. Examination of 21 representative Schistosoma samples from 15 geographical localities in seven endemic countries validated the value of the HRM detection assay and proved its reliability. The melting curves were characterized by peaks of 83.65 °C for S. japonicum and S. mekongi, 85.65 °C for S. mansoni, and 85.85 °C for S. haematobium. The present study developed a real-time PCR coupled with HRM analysis assay for detection and differential identification of S. mansoni, S. haematobium, S. japonicum, and S. mekongi. This method is rapid, sensitive, and inexpensive. It has important implications for epidemiological studies of Schistosoma.

  16. Method for rapid detection and identification of chaetomium and evaluation of resistance to peracetic acid.

    Science.gov (United States)

    Nakayama, Motokazu; Hosoya, Kouichi; Tomiyama, Daisuke; Tsugukuni, Takashi; Matsuzawa, Tetsuhiro; Imanishi, Yumi; Yaguchi, Takashi

    2013-06-01

    In the beverage industry, peracetic acid has been increasingly used as a disinfectant for the filling machinery and environment due to merits of leaving no residue, it is safe for humans, and its antiseptic effect against fungi and endospores of bacteria. Recently, Chaetomium globosum and Chaetomium funicola were reported resistant to peracetic acid; however, little is known concerning the detail of peracetic acid resistance. Therefore, we assessed the peracetic acid resistance of the species of Chaetomium and related genera under identical conditions and made a thorough observation of the microstructure of their ascospores by transmission electron microscopy. The results of analyses revealed that C. globosum and C. funicola showed the high resistance to peracetic acid (a 1-D antiseptic effect after 900 s and 3-D antiseptic effect after 900 s) and had thick cell walls of ascospores that can impede the action mechanism of peracetic acid. We also developed specific primers to detect the C. globosum clade and identify C. funicola by using PCR to amplify the β-tubulin gene. PCR with the primer sets designed for C. globosum (Chae 4F/4R) and C. funicola (Cfu 2F/2R) amplified PCR products specific for the C. globosum clade and C. funicola, respectively. PCR with these two primer sets did not detect other fungi involved in food spoilage and environmental contamination. This detection and identification method is rapid and simple, with extremely high specificity.

  17. Mobile biometric device (MBD) technology :

    Energy Technology Data Exchange (ETDEWEB)

    Aldridge, Chris D.

    2013-06-01

    Mobile biometric devices (MBDs) capable of both enrolling individuals in databases and performing identification checks of subjects in the field are seen as an important capability for military, law enforcement, and homeland security operations. The technology is advancing rapidly. The Department of Homeland Security Science and Technology Directorate through an Interagency Agreement with Sandia sponsored a series of pilot projects to obtain information for the first responder law enforcement community on further identification of requirements for mobile biometric device technology. Working with 62 different jurisdictions, including components of the Department of Homeland Security, Sandia delivered a series of reports on user operation of state-of-the-art mobile biometric devices. These reports included feedback information on MBD usage in both operational and exercise scenarios. The findings and conclusions of the project address both the limitations and possibilities of MBD technology to improve operations. Evidence of these possibilities can be found in the adoption of this technology by many agencies today and the cooperation of several law enforcement agencies in both participating in the pilot efforts and sharing of information about their own experiences in efforts undertaken separately.

  18. Improving substructure identification accuracy of shear structures using virtual control system

    Science.gov (United States)

    Zhang, Dongyu; Yang, Yang; Wang, Tingqiang; Li, Hui

    2018-02-01

    Substructure identification is a powerful tool to identify the parameters of a complex structure. Previously, the authors developed an inductive substructure identification method for shear structures. The identification error analysis showed that the identification accuracy of this method is significantly influenced by the magnitudes of two key structural responses near a certain frequency; if these responses are unfavorable, the method cannot provide accurate estimation results. In this paper, a novel method is proposed to improve the substructure identification accuracy by introducing a virtual control system (VCS) into the structure. A virtual control system is a self-balanced system, which consists of some control devices and a set of self-balanced forces. The self-balanced forces counterbalance the forces that the control devices apply on the structure. The control devices are combined with the structure to form a controlled structure used to replace the original structure in the substructure identification; and the self-balance forces are treated as known external excitations to the controlled structure. By optimally tuning the VCS’s parameters, the dynamic characteristics of the controlled structure can be changed such that the original structural responses become more favorable for the substructure identification and, thus, the identification accuracy is improved. A numerical example of 6-story shear structure is utilized to verify the effectiveness of the VCS based controlled substructure identification method. Finally, shake table tests are conducted on a 3-story structural model to verify the efficacy of the VCS to enhance the identification accuracy of the structural parameters.

  19. Lightweight autonomous chemical identification system (LACIS)

    Science.gov (United States)

    Lozos, George; Lin, Hai; Burch, Timothy

    2012-06-01

    Smiths Detection and Intelligent Optical Systems have developed prototypes for the Lightweight Autonomous Chemical Identification System (LACIS) for the US Department of Homeland Security. LACIS is to be a handheld detection system for Chemical Warfare Agents (CWAs) and Toxic Industrial Chemicals (TICs). LACIS is designed to have a low limit of detection and rapid response time for use by emergency responders and could allow determination of areas having dangerous concentration levels and if protective garments will be required. Procedures for protection of responders from hazardous materials incidents require the use of protective equipment until such time as the hazard can be assessed. Such accurate analysis can accelerate operations and increase effectiveness. LACIS is to be an improved point detector employing novel CBRNE detection modalities that includes a militaryproven ruggedized ion mobility spectrometer (IMS) with an array of electro-resistive sensors to extend the range of chemical threats detected in a single device. It uses a novel sensor data fusion and threat classification architecture to interpret the independent sensor responses and provide robust detection at low levels in complex backgrounds with minimal false alarms. The performance of LACIS prototypes have been characterized in independent third party laboratory tests at the Battelle Memorial Institute (BMI, Columbus, OH) and indoor and outdoor field tests at the Nevada National Security Site (NNSS). LACIS prototypes will be entering operational assessment by key government emergency response groups to determine its capabilities versus requirements.

  20. Portable modular detection system

    Science.gov (United States)

    Brennan, James S [Rodeo, CA; Singh, Anup [Danville, CA; Throckmorton, Daniel J [Tracy, CA; Stamps, James F [Livermore, CA

    2009-10-13

    Disclosed herein are portable and modular detection devices and systems for detecting electromagnetic radiation, such as fluorescence, from an analyte which comprises at least one optical element removably attached to at least one alignment rail. Also disclosed are modular detection devices and systems having an integrated lock-in amplifier and spatial filter and assay methods using the portable and modular detection devices.