WorldWideScience

Sample records for dependent variables results

  1. Validity of a Residualized Dependent Variable after Pretest Covariance Adjustments: Still the Same Variable?

    Science.gov (United States)

    Nimon, Kim; Henson, Robin K.

    2015-01-01

    The authors empirically examined whether the validity of a residualized dependent variable after covariance adjustment is comparable to that of the original variable of interest. When variance of a dependent variable is removed as a result of one or more covariates, the residual variance may not reflect the same meaning. Using the pretest-posttest…

  2. Benford's law and continuous dependent random variables

    Science.gov (United States)

    Becker, Thealexa; Burt, David; Corcoran, Taylor C.; Greaves-Tunnell, Alec; Iafrate, Joseph R.; Jing, Joy; Miller, Steven J.; Porfilio, Jaclyn D.; Ronan, Ryan; Samranvedhya, Jirapat; Strauch, Frederick W.; Talbut, Blaine

    2018-01-01

    Many mathematical, man-made and natural systems exhibit a leading-digit bias, where a first digit (base 10) of 1 occurs not 11% of the time, as one would expect if all digits were equally likely, but rather 30%. This phenomenon is known as Benford's Law. Analyzing which datasets adhere to Benford's Law and how quickly Benford behavior sets in are the two most important problems in the field. Most previous work studied systems of independent random variables, and relied on the independence in their analyses. Inspired by natural processes such as particle decay, we study the dependent random variables that emerge from models of decomposition of conserved quantities. We prove that in many instances the distribution of lengths of the resulting pieces converges to Benford behavior as the number of divisions grow, and give several conjectures for other fragmentation processes. The main difficulty is that the resulting random variables are dependent. We handle this by using tools from Fourier analysis and irrationality exponents to obtain quantified convergence rates as well as introducing and developing techniques to measure and control the dependencies. The construction of these tools is one of the major motivations of this work, as our approach can be applied to many other dependent systems. As an example, we show that the n ! entries in the determinant expansions of n × n matrices with entries independently drawn from nice random variables converges to Benford's Law.

  3. Future-dependent Flow Policies with Prophetic Variables

    DEFF Research Database (Denmark)

    Li, Ximeng; Nielson, Flemming; Nielson, Hanne Riis

    2016-01-01

    future-dependent flow policies- policies that can depend on not only the current values of variables, but also their final values. The final values are referred to using what we call prophetic variables, just as the initial values can be referenced using logical variables in Hoare logic. We develop...... and enforce a notion of future-dependent security for open systems, in the spirit of "non-deducibility on strategies". We also illustrate our approach in scenarios where future-dependency has advantages over present-dependency and avoids mixtures of upgradings and downgradings....

  4. Reward-dependent modulation of movement variability.

    Science.gov (United States)

    Pekny, Sarah E; Izawa, Jun; Shadmehr, Reza

    2015-03-04

    Movement variability is often considered an unwanted byproduct of a noisy nervous system. However, variability can signal a form of implicit exploration, indicating that the nervous system is intentionally varying the motor commands in search of actions that yield the greatest success. Here, we investigated the role of the human basal ganglia in controlling reward-dependent motor variability as measured by trial-to-trial changes in performance during a reaching task. We designed an experiment in which the only performance feedback was success or failure and quantified how reach variability was modulated as a function of the probability of reward. In healthy controls, reach variability increased as the probability of reward decreased. Control of variability depended on the history of past rewards, with the largest trial-to-trial changes occurring immediately after an unrewarded trial. In contrast, in participants with Parkinson's disease, a known example of basal ganglia dysfunction, reward was a poor modulator of variability; that is, the patients showed an impaired ability to increase variability in response to decreases in the probability of reward. This was despite the fact that, after rewarded trials, reach variability in the patients was comparable to healthy controls. In summary, we found that movement variability is partially a form of exploration driven by the recent history of rewards. When the function of the human basal ganglia is compromised, the reward-dependent control of movement variability is impaired, particularly affecting the ability to increase variability after unsuccessful outcomes. Copyright © 2015 the authors 0270-6474/15/354015-10$15.00/0.

  5. Effects of variable transformations on errors in FORM results

    International Nuclear Information System (INIS)

    Qin Quan; Lin Daojin; Mei Gang; Chen Hao

    2006-01-01

    On the basis of studies on second partial derivatives of the variable transformation functions for nine different non-normal variables the paper comprehensively discusses the effects of the transformation on FORM results and shows that senses and values of the errors in FORM results depend on distributions of the basic variables, whether resistances or actions basic variables represent, and the design point locations in the standard normal space. The transformations of the exponential or Gamma resistance variables can generate +24% errors in the FORM failure probability, and the transformation of Frechet action variables could generate -31% errors

  6. Non-uniform approximations for sums of discrete m-dependent random variables

    OpenAIRE

    Vellaisamy, P.; Cekanavicius, V.

    2013-01-01

    Non-uniform estimates are obtained for Poisson, compound Poisson, translated Poisson, negative binomial and binomial approximations to sums of of m-dependent integer-valued random variables. Estimates for Wasserstein metric also follow easily from our results. The results are then exemplified by the approximation of Poisson binomial distribution, 2-runs and $m$-dependent $(k_1,k_2)$-events.

  7. [Correlation coefficient-based classification method of hydrological dependence variability: With auto-regression model as example].

    Science.gov (United States)

    Zhao, Yu Xi; Xie, Ping; Sang, Yan Fang; Wu, Zi Yi

    2018-04-01

    Hydrological process evaluation is temporal dependent. Hydrological time series including dependence components do not meet the data consistency assumption for hydrological computation. Both of those factors cause great difficulty for water researches. Given the existence of hydrological dependence variability, we proposed a correlationcoefficient-based method for significance evaluation of hydrological dependence based on auto-regression model. By calculating the correlation coefficient between the original series and its dependence component and selecting reasonable thresholds of correlation coefficient, this method divided significance degree of dependence into no variability, weak variability, mid variability, strong variability, and drastic variability. By deducing the relationship between correlation coefficient and auto-correlation coefficient in each order of series, we found that the correlation coefficient was mainly determined by the magnitude of auto-correlation coefficient from the 1 order to p order, which clarified the theoretical basis of this method. With the first-order and second-order auto-regression models as examples, the reasonability of the deduced formula was verified through Monte-Carlo experiments to classify the relationship between correlation coefficient and auto-correlation coefficient. This method was used to analyze three observed hydrological time series. The results indicated the coexistence of stochastic and dependence characteristics in hydrological process.

  8. Problems Identifying Independent and Dependent Variables

    Science.gov (United States)

    Leatham, Keith R.

    2012-01-01

    This paper discusses one step from the scientific method--that of identifying independent and dependent variables--from both scientific and mathematical perspectives. It begins by analyzing an episode from a middle school mathematics classroom that illustrates the need for students and teachers alike to develop a robust understanding of…

  9. Equivalent conditions of complete moment convergence for extended negatively dependent random variables

    Directory of Open Access Journals (Sweden)

    Qunying Wu

    2017-05-01

    Full Text Available Abstract In this paper, we study the equivalent conditions of complete moment convergence for sequences of identically distributed extended negatively dependent random variables. As a result, we extend and generalize some results of complete moment convergence obtained by Chow (Bull. Inst. Math. Acad. Sin. 16:177-201, 1988 and Li and Spătaru (J. Theor. Probab. 18:933-947, 2005 from the i.i.d. case to extended negatively dependent sequences.

  10. Hoeffding’s Inequality for Sums of Dependent Random Variables

    Czech Academy of Sciences Publication Activity Database

    Pelekis, Christos; Ramon, J.

    2017-01-01

    Roč. 14, č. 6 (2017), č. článku 243. ISSN 1660-5446 Institutional support: RVO:67985807 Keywords : dependent random variables * Hoeffding’s inequality * k-wise independent random variables * martingale differences Subject RIV: BA - General Mathematics OBOR OECD: Pure mathematics Impact factor: 0.868, year: 2016

  11. Fixed transaction costs and modelling limited dependent variables

    NARCIS (Netherlands)

    Hempenius, A.L.

    1994-01-01

    As an alternative to the Tobit model, for vectors of limited dependent variables, I suggest a model, which follows from explicitly using fixed costs, if appropriate of course, in the utility function of the decision-maker.

  12. Quadratic time dependent Hamiltonians and separation of variables

    International Nuclear Information System (INIS)

    Anzaldo-Meneses, A.

    2017-01-01

    Time dependent quantum problems defined by quadratic Hamiltonians are solved using canonical transformations. The Green’s function is obtained and a comparison with the classical Hamilton–Jacobi method leads to important geometrical insights like exterior differential systems, Monge cones and time dependent Gaussian metrics. The Wei–Norman approach is applied using unitary transformations defined in terms of generators of the associated Lie groups, here the semi-direct product of the Heisenberg group and the symplectic group. A new explicit relation for the unitary transformations is given in terms of a finite product of elementary transformations. The sequential application of adequate sets of unitary transformations leads naturally to a new separation of variables method for time dependent Hamiltonians, which is shown to be related to the Inönü–Wigner contraction of Lie groups. The new method allows also a better understanding of interacting particles or coupled modes and opens an alternative way to analyze topological phases in driven systems. - Highlights: • Exact unitary transformation reducing time dependent quadratic quantum Hamiltonian to zero. • New separation of variables method and simultaneous uncoupling of modes. • Explicit examples of transformations for one to four dimensional problems. • New general evolution equation for quadratic form in the action, respectively Green’s function.

  13. ABCB1 genetic variability and methadone dosage requirements in opioid-dependent individuals.

    Science.gov (United States)

    Coller, Janet K; Barratt, Daniel T; Dahlen, Karianne; Loennechen, Morten H; Somogyi, Andrew A

    2006-12-01

    The most common treatment for opioid dependence is substitution therapy with another opioid such as methadone. The methadone dosage is individualized but highly variable, and program retention rates are low due in part to nonoptimal dosing resulting in withdrawal symptoms and further heroin craving and use. Methadone is a substrate for the P-glycoprotein transporter, encoded by the ABCB1 gene, which regulates central nervous system exposure. This retrospective study aimed to investigate the influence of ABCB1 genetic variability on methadone dose requirements. Genomic deoxyribonucleic acid was isolated from opioid-dependent subjects (n = 60) and non-opioid-dependent control subjects (n = 60), and polymerase chain reaction-restriction fragment length polymorphism and allele-specific polymerase chain reaction were used to determine the presence of single nucleotide polymorphisms at positions 61, 1199, 1236, 2677, and 3435. ABCB1 haplotypes were inferred with PHASE software (version 2.1). There were no significant differences in the allele or genotype frequencies of the individual single nucleotide polymorphisms or haplotypes between the 2 populations. ABCB1 genetic variability influenced daily methadone dose requirements, such that subjects carrying 2 copies of the wild-type haplotype required higher doses compared with those with 1 copy and those with no copies (98.3 +/- 10.4, 58.6 +/- 20.9, and 55.4 +/- 26.1 mg/d, respectively; P = .029). In addition, carriers of the AGCTT haplotype required significantly lower doses than noncarriers (38.0 +/- 16.8 and 61.3 +/- 24.6 mg/d, respectively; P = .04). Although ABCB1 genetic variability is not related to the development of opioid dependence, identification of variant haplotypes may, after larger prospective studies have been performed, provide clinicians with a tool for methadone dosage individualization.

  14. Statistical Dependence of Pipe Breaks on Explanatory Variables

    Directory of Open Access Journals (Sweden)

    Patricia Gómez-Martínez

    2017-02-01

    Full Text Available Aging infrastructure is the main challenge currently faced by water suppliers. Estimation of assets lifetime requires reliable criteria to plan assets repair and renewal strategies. To do so, pipe break prediction is one of the most important inputs. This paper analyzes the statistical dependence of pipe breaks on explanatory variables, determining their optimal combination and quantifying their influence on failure prediction accuracy. A large set of registered data from Madrid water supply network, managed by Canal de Isabel II, has been filtered, classified and studied. Several statistical Bayesian models have been built and validated from the available information with a technique that combines reference periods of time as well as geographical location. Statistical models of increasing complexity are built from zero up to five explanatory variables following two approaches: a set of independent variables or a combination of two joint variables plus an additional number of independent variables. With the aim of finding the variable combination that provides the most accurate prediction, models are compared following an objective validation procedure based on the model skill to predict the number of pipe breaks in a large set of geographical locations. As expected, model performance improves as the number of explanatory variables increases. However, the rate of improvement is not constant. Performance metrics improve significantly up to three variables, but the tendency is softened for higher order models, especially in trunk mains where performance is reduced. Slight differences are found between trunk mains and distribution lines when selecting the most influent variables and models.

  15. Value of Construction Company and its Dependence on Significant Variables

    Science.gov (United States)

    Vítková, E.; Hromádka, V.; Ondrušková, E.

    2017-10-01

    The paper deals with the value of the construction company assessment respecting usable approaches and determinable variables. The reasons of the value of the construction company assessment are different, but the most important reasons are the sale or the purchase of the company, the liquidation of the company, the fusion of the company with another subject or the others. According the reason of the value assessment it is possible to determine theoretically different approaches for valuation, mainly it concerns about the yield method of valuation and the proprietary method of valuation. Both approaches are dependant of detailed input variables, which quality will influence the final assessment of the company´s value. The main objective of the paper is to suggest, according to the analysis, possible ways of input variables, mainly in the form of expected cash-flows or the profit, determination. The paper is focused mainly on methods of time series analysis, regression analysis and mathematical simulation utilization. As the output, the results of the analysis on the case study will be demonstrated.

  16. Variability analysis of AGN: a review of results using new statistical criteria

    Science.gov (United States)

    Zibecchi, L.; Andruchow, I.; Cellone, S. A.; Romero, G. E.; Combi, J. A.

    We present here a re-analysis of the variability results of a sample of active galactic nuclei (AGN), which have been observed on several sessions with the 2.15 m "Jorge Sahade" telescope (CASLEO), San Juan, Argentina, and whose results are published (Romero et al. 1999, 2000, 2002; Cellone et al. 2000). The motivation for this new analysis is the implementation, dur- ing the last years, of improvements in the statistical criteria applied, taking quantitatively into account the incidence of the photometric errors (Cellone et al. 2007). This work is framed as a first step in an integral study on the statistical estimators of AGN variability. This study is motivated by the great diversity of statistical tests that have been proposed to analyze the variability of these objects. Since we note that, in some cases, the results of the object variability depend on the test used, we attempt to make a com- parative study of the various tests and analyze, under the given conditions, which of them is the most efficient and reliable.

  17. An edgeworth expansion for a sum of M-Dependent random variables

    Directory of Open Access Journals (Sweden)

    Wan Soo Rhee

    1985-01-01

    Full Text Available Given a sequence X1,X2,…,Xn of m-dependent random variables with moments of order 3+α (0<α≦1, we give an Edgeworth expansion of the distribution of Sσ−1(S=X1+X2+…+Xn, σ2=ES2 under the assumption that E[exp(it Sσ1] is small away from the origin. The result is of the best possible order.

  18. Using k-dependence causal forest to mine the most significant dependency relationships among clinical variables for thyroid disease diagnosis.

    Directory of Open Access Journals (Sweden)

    LiMin Wang

    Full Text Available Numerous data mining models have been proposed to construct computer-aided medical expert systems. Bayesian network classifiers (BNCs are more distinct and understandable than other models. To graphically describe the dependency relationships among clinical variables for thyroid disease diagnosis and ensure the rationality of the diagnosis results, the proposed k-dependence causal forest (KCF model generates a series of submodels in the framework of maximum spanning tree (MST and demonstrates stronger dependence representation. Friedman test on 12 UCI datasets shows that KCF has classification accuracy advantage over the other state-of-the-art BNCs, such as Naive Bayes, tree augmented Naive Bayes, and k-dependence Bayesian classifier. Our extensive experimental comparison on 4 medical datasets also proves the feasibility and effectiveness of KCF in terms of sensitivity and specificity.

  19. New Results On the Sum of Two Generalized Gaussian Random Variables

    KAUST Repository

    Soury, Hamza

    2015-01-01

    We propose in this paper a new method to compute the characteristic function (CF) of generalized Gaussian (GG) random variable in terms of the Fox H function. The CF of the sum of two independent GG random variables is then deduced. Based on this results, the probability density function (PDF) and the cumulative distribution function (CDF) of the sum distribution are obtained. These functions are expressed in terms of the bivariate Fox H function. Next, the statistics of the distribution of the sum, such as the moments, the cumulant, and the kurtosis, are analyzed and computed. Due to the complexity of bivariate Fox H function, a solution to reduce such complexity is to approximate the sum of two independent GG random variables by one GG random variable with suitable shape factor. The approximation method depends on the utility of the system so three methods of estimate the shape factor are studied and presented.

  20. New Results on the Sum of Two Generalized Gaussian Random Variables

    KAUST Repository

    Soury, Hamza

    2016-01-06

    We propose in this paper a new method to compute the characteristic function (CF) of generalized Gaussian (GG) random variable in terms of the Fox H function. The CF of the sum of two independent GG random variables is then deduced. Based on this results, the probability density function (PDF) and the cumulative distribution function (CDF) of the sum distribution are obtained. These functions are expressed in terms of the bivariate Fox H function. Next, the statistics of the distribution of the sum, such as the moments, the cumulant, and the kurtosis, are analyzed and computed. Due to the complexity of bivariate Fox H function, a solution to reduce such complexity is to approximate the sum of two independent GG random variables by one GG random variable with suitable shape factor. The approximation method depends on the utility of the system so three methods of estimate the shape factor are studied and presented [1].

  1. New Results on the Sum of Two Generalized Gaussian Random Variables

    KAUST Repository

    Soury, Hamza; Alouini, Mohamed-Slim

    2016-01-01

    We propose in this paper a new method to compute the characteristic function (CF) of generalized Gaussian (GG) random variable in terms of the Fox H function. The CF of the sum of two independent GG random variables is then deduced. Based on this results, the probability density function (PDF) and the cumulative distribution function (CDF) of the sum distribution are obtained. These functions are expressed in terms of the bivariate Fox H function. Next, the statistics of the distribution of the sum, such as the moments, the cumulant, and the kurtosis, are analyzed and computed. Due to the complexity of bivariate Fox H function, a solution to reduce such complexity is to approximate the sum of two independent GG random variables by one GG random variable with suitable shape factor. The approximation method depends on the utility of the system so three methods of estimate the shape factor are studied and presented [1].

  2. Energy decay of a variable-coefficient wave equation with nonlinear time-dependent localized damping

    Directory of Open Access Journals (Sweden)

    Jieqiong Wu

    2015-09-01

    Full Text Available We study the energy decay for the Cauchy problem of the wave equation with nonlinear time-dependent and space-dependent damping. The damping is localized in a bounded domain and near infinity, and the principal part of the wave equation has a variable-coefficient. We apply the multiplier method for variable-coefficient equations, and obtain an energy decay that depends on the property of the coefficient of the damping term.

  3. Quadratic time dependent Hamiltonians and separation of variables

    Science.gov (United States)

    Anzaldo-Meneses, A.

    2017-06-01

    Time dependent quantum problems defined by quadratic Hamiltonians are solved using canonical transformations. The Green's function is obtained and a comparison with the classical Hamilton-Jacobi method leads to important geometrical insights like exterior differential systems, Monge cones and time dependent Gaussian metrics. The Wei-Norman approach is applied using unitary transformations defined in terms of generators of the associated Lie groups, here the semi-direct product of the Heisenberg group and the symplectic group. A new explicit relation for the unitary transformations is given in terms of a finite product of elementary transformations. The sequential application of adequate sets of unitary transformations leads naturally to a new separation of variables method for time dependent Hamiltonians, which is shown to be related to the Inönü-Wigner contraction of Lie groups. The new method allows also a better understanding of interacting particles or coupled modes and opens an alternative way to analyze topological phases in driven systems.

  4. How a dependent's variable non-randomness affects taper equation ...

    African Journals Online (AJOL)

    In order to apply the least squares method in regression analysis, the values of the dependent variable Y should be random. In an example of regression analysis linear and nonlinear taper equations, which estimate the diameter of the tree dhi at any height of the tree hi, were compared. For each tree the diameter at the ...

  5. Motivation as an independent and a dependent variable in medical education: a review of the literature.

    Science.gov (United States)

    Kusurkar, R A; Ten Cate, Th J; van Asperen, M; Croiset, G

    2011-01-01

    Motivation in learning behaviour and education is well-researched in general education, but less in medical education. To answer two research questions, 'How has the literature studied motivation as either an independent or dependent variable? How is motivation useful in predicting and understanding processes and outcomes in medical education?' in the light of the Self-determination Theory (SDT) of motivation. A literature search performed using the PubMed, PsycINFO and ERIC databases resulted in 460 articles. The inclusion criteria were empirical research, specific measurement of motivation and qualitative research studies which had well-designed methodology. Only studies related to medical students/school were included. Findings of 56 articles were included in the review. Motivation as an independent variable appears to affect learning and study behaviour, academic performance, choice of medicine and specialty within medicine and intention to continue medical study. Motivation as a dependent variable appears to be affected by age, gender, ethnicity, socioeconomic status, personality, year of medical curriculum and teacher and peer support, all of which cannot be manipulated by medical educators. Motivation is also affected by factors that can be influenced, among which are, autonomy, competence and relatedness, which have been described as the basic psychological needs important for intrinsic motivation according to SDT. Motivation is an independent variable in medical education influencing important outcomes and is also a dependent variable influenced by autonomy, competence and relatedness. This review finds some evidence in support of the validity of SDT in medical education.

  6. The discovery of timescale-dependent color variability of quasars

    Energy Technology Data Exchange (ETDEWEB)

    Sun, Yu-Han; Wang, Jun-Xian; Chen, Xiao-Yang [CAS Key Laboratory for Research in Galaxies and Cosmology, Department of Astronomy, University of Science and Technology of China, Hefei, Anhui 230026 (China); Zheng, Zhen-Ya, E-mail: sunyh92@mail.ustc.edu.cn, E-mail: jxw@ustc.edu.cn [School of Earth and Space Exploration, Arizona State University, Tempe, AZ 85287 (United States)

    2014-09-01

    Quasars are variable on timescales from days to years in UV/optical and generally appear bluer while they brighten. The physics behind the variations in fluxes and colors remains unclear. Using Sloan Digital Sky Survey g- and r-band photometric monitoring data for quasars in Stripe 82, we find that although the flux variation amplitude increases with timescale, the color variability exhibits the opposite behavior. The color variability of quasars is prominent at timescales as short as ∼10 days, but gradually reduces toward timescales up to years. In other words, the variable emission at shorter timescales is bluer than that at longer timescales. This timescale dependence is clearly and consistently detected at all redshifts from z = 0 to 3.5; thus, it cannot be due to contamination to broadband photometry from emission lines that do not respond to fast continuum variations. The discovery directly rules out the possibility that simply attributes the color variability to contamination from a non-variable redder component such as the host galaxy. It cannot be interpreted as changes in global accretion rate either. The thermal accretion disk fluctuation model is favored in the sense that fluctuations in the inner, hotter region of the disk are responsible for short-term variations, while longer-term and stronger variations are expected from the larger and cooler disk region. An interesting implication is that one can use quasar variations at different timescales to probe disk emission at different radii.

  7. Size-dependent standard deviation for growth rates: empirical results and theoretical modeling.

    Science.gov (United States)

    Podobnik, Boris; Horvatic, Davor; Pammolli, Fabio; Wang, Fengzhong; Stanley, H Eugene; Grosse, I

    2008-05-01

    We study annual logarithmic growth rates R of various economic variables such as exports, imports, and foreign debt. For each of these variables we find that the distributions of R can be approximated by double exponential (Laplace) distributions in the central parts and power-law distributions in the tails. For each of these variables we further find a power-law dependence of the standard deviation sigma(R) on the average size of the economic variable with a scaling exponent surprisingly close to that found for the gross domestic product (GDP) [Phys. Rev. Lett. 81, 3275 (1998)]. By analyzing annual logarithmic growth rates R of wages of 161 different occupations, we find a power-law dependence of the standard deviation sigma(R) on the average value of the wages with a scaling exponent beta approximately 0.14 close to those found for the growth of exports, imports, debt, and the growth of the GDP. In contrast to these findings, we observe for payroll data collected from 50 states of the USA that the standard deviation sigma(R) of the annual logarithmic growth rate R increases monotonically with the average value of payroll. However, also in this case we observe a power-law dependence of sigma(R) on the average payroll with a scaling exponent beta approximately -0.08 . Based on these observations we propose a stochastic process for multiple cross-correlated variables where for each variable (i) the distribution of logarithmic growth rates decays exponentially in the central part, (ii) the distribution of the logarithmic growth rate decays algebraically in the far tails, and (iii) the standard deviation of the logarithmic growth rate depends algebraically on the average size of the stochastic variable.

  8. Size-dependent standard deviation for growth rates: Empirical results and theoretical modeling

    Science.gov (United States)

    Podobnik, Boris; Horvatic, Davor; Pammolli, Fabio; Wang, Fengzhong; Stanley, H. Eugene; Grosse, I.

    2008-05-01

    We study annual logarithmic growth rates R of various economic variables such as exports, imports, and foreign debt. For each of these variables we find that the distributions of R can be approximated by double exponential (Laplace) distributions in the central parts and power-law distributions in the tails. For each of these variables we further find a power-law dependence of the standard deviation σ(R) on the average size of the economic variable with a scaling exponent surprisingly close to that found for the gross domestic product (GDP) [Phys. Rev. Lett. 81, 3275 (1998)]. By analyzing annual logarithmic growth rates R of wages of 161 different occupations, we find a power-law dependence of the standard deviation σ(R) on the average value of the wages with a scaling exponent β≈0.14 close to those found for the growth of exports, imports, debt, and the growth of the GDP. In contrast to these findings, we observe for payroll data collected from 50 states of the USA that the standard deviation σ(R) of the annual logarithmic growth rate R increases monotonically with the average value of payroll. However, also in this case we observe a power-law dependence of σ(R) on the average payroll with a scaling exponent β≈-0.08 . Based on these observations we propose a stochastic process for multiple cross-correlated variables where for each variable (i) the distribution of logarithmic growth rates decays exponentially in the central part, (ii) the distribution of the logarithmic growth rate decays algebraically in the far tails, and (iii) the standard deviation of the logarithmic growth rate depends algebraically on the average size of the stochastic variable.

  9. Natural variability of biochemical biomarkers in the macro-zoobenthos: Dependence on life stage and environmental factors.

    Science.gov (United States)

    Scarduelli, Lucia; Giacchini, Roberto; Parenti, Paolo; Migliorati, Sonia; Di Brisco, Agnese Maria; Vighi, Marco

    2017-11-01

    Biomarkers are widely used in ecotoxicology as indicators of exposure to toxicants. However, their ability to provide ecologically relevant information remains controversial. One of the major problems is understanding whether the measured responses are determined by stress factors or lie within the natural variability range. In a previous work, the natural variability of enzymatic levels in invertebrates sampled in pristine rivers was proven to be relevant across both space and time. In the present study, the experimental design was improved by considering different life stages of the selected taxa and by measuring more environmental parameters. The experimental design considered sampling sites in 2 different rivers, 8 sampling dates covering the whole seasonal cycle, 4 species from 3 different taxonomic groups (Plecoptera, Perla grandis; Ephemeroptera, Baetis alpinus and Epeorus alpicula; Tricoptera, Hydropsyche pellucidula), different life stages for each species, and 4 enzymes (acetylcholinesterase, glutathione S-transferase, alkaline phosphatase, and catalase). Biomarker levels were related to environmental (physicochemical) parameters to verify any kind of dependence. Data were statistically elaborated using hierarchical multilevel Bayesian models. Natural variability was found to be relevant across both space and time. The results of the present study proved that care should be paid when interpreting biomarker results. Further research is needed to better understand the dependence of the natural variability on environmental parameters. Environ Toxicol Chem 2017;36:3158-3167. © 2017 SETAC. © 2017 SETAC.

  10. Assessment of variability in the hydrological cycle of the Loess Plateau, China: examining dependence structures of hydrological processes

    Science.gov (United States)

    Guo, A.; Wang, Y.

    2017-12-01

    Investigating variability in dependence structures of hydrological processes is of critical importance for developing an understanding of mechanisms of hydrological cycles in changing environments. In focusing on this topic, present work involves the following: (1) identifying and eliminating serial correlation and conditional heteroscedasticity in monthly streamflow (Q), precipitation (P) and potential evapotranspiration (PE) series using the ARMA-GARCH model (ARMA: autoregressive moving average; GARCH: generalized autoregressive conditional heteroscedasticity); (2) describing dependence structures of hydrological processes using partial copula coupled with the ARMA-GARCH model and identifying their variability via copula-based likelihood-ratio test method; and (3) determining conditional probability of annual Q under different climate scenarios on account of above results. This framework enables us to depict hydrological variables in the presence of conditional heteroscedasticity and to examine dependence structures of hydrological processes while excluding the influence of covariates by using partial copula-based ARMA-GARCH model. Eight major catchments across the Loess Plateau (LP) are used as study regions. Results indicate that (1) The occurrence of change points in dependence structures of Q and P (PE) varies across the LP. Change points of P-PE dependence structures in all regions almost fully correspond to the initiation of global warming, i.e., the early 1980s. (3) Conditional probabilities of annual Q under various P and PE scenarios are estimated from the 3-dimensional joint distribution of (Q, P and PE) based on the above change points. These findings shed light on mechanisms of the hydrological cycle and can guide water supply planning and management, particularly in changing environments.

  11. Phase dependence of transport-aperture coordination variability reveals control strategy of reach-to-grasp movements.

    Science.gov (United States)

    Rand, Miya K; Shimansky, Y P; Hossain, Abul B M I; Stelmach, George E

    2010-11-01

    Based on an assumption of movement control optimality in reach-to-grasp movements, we have recently developed a mathematical model of transport-aperture coordination (TAC), according to which the hand-target distance is a function of hand velocity and acceleration, aperture magnitude, and aperture velocity and acceleration (Rand et al. in Exp Brain Res 188:263-274, 2008). Reach-to-grasp movements were performed by young adults under four different reaching speeds and two different transport distances. The residual error magnitude of fitting the above model to data across different trials and subjects was minimal for the aperture-closure phase, but relatively much greater for the aperture-opening phase, indicating considerable difference in TAC variability between those phases. This study's goal is to identify the main reasons for that difference and obtain insights into the control strategy of reach-to-grasp movements. TAC variability within the aperture-opening phase of a single trial was found minimal, indicating that TAC variability between trials was not due to execution noise, but rather a result of inter-trial and inter-subject variability of motor plan. At the same time, the dependence of the extent of trial-to-trial variability of TAC in that phase on the speed of hand transport was sharply inconsistent with the concept of speed-accuracy trade-off: the lower the speed, the larger the variability. Conversely, the dependence of the extent of TAC variability in the aperture-closure phase on hand transport speed was consistent with that concept. Taking into account recent evidence that the cost of neural information processing is substantial for movement planning, the dependence of TAC variability in the aperture-opening phase on task performance conditions suggests that it is not the movement time that the CNS saves in that phase, but the cost of neuro-computational resources and metabolic energy required for TAC regulation in that phase. Thus, the CNS

  12. Human phoneme recognition depending on speech-intrinsic variability.

    Science.gov (United States)

    Meyer, Bernd T; Jürgens, Tim; Wesker, Thorsten; Brand, Thomas; Kollmeier, Birger

    2010-11-01

    The influence of different sources of speech-intrinsic variation (speaking rate, effort, style and dialect or accent) on human speech perception was investigated. In listening experiments with 16 listeners, confusions of consonant-vowel-consonant (CVC) and vowel-consonant-vowel (VCV) sounds in speech-weighted noise were analyzed. Experiments were based on the OLLO logatome speech database, which was designed for a man-machine comparison. It contains utterances spoken by 50 speakers from five dialect/accent regions and covers several intrinsic variations. By comparing results depending on intrinsic and extrinsic variations (i.e., different levels of masking noise), the degradation induced by variabilities can be expressed in terms of the SNR. The spectral level distance between the respective speech segment and the long-term spectrum of the masking noise was found to be a good predictor for recognition rates, while phoneme confusions were influenced by the distance to spectrally close phonemes. An analysis based on transmitted information of articulatory features showed that voicing and manner of articulation are comparatively robust cues in the presence of intrinsic variations, whereas the coding of place is more degraded. The database and detailed results have been made available for comparisons between human speech recognition (HSR) and automatic speech recognizers (ASR).

  13. Delay-slope-dependent stability results of recurrent neural networks.

    Science.gov (United States)

    Li, Tao; Zheng, Wei Xing; Lin, Chong

    2011-12-01

    By using the fact that the neuron activation functions are sector bounded and nondecreasing, this brief presents a new method, named the delay-slope-dependent method, for stability analysis of a class of recurrent neural networks with time-varying delays. This method includes more information on the slope of neuron activation functions and fewer matrix variables in the constructed Lyapunov-Krasovskii functional. Then some improved delay-dependent stability criteria with less computational burden and conservatism are obtained. Numerical examples are given to illustrate the effectiveness and the benefits of the proposed method.

  14. Punishment induced behavioural and neurophysiological variability reveals dopamine-dependent selection of kinematic movement parameters

    Science.gov (United States)

    Galea, Joseph M.; Ruge, Diane; Buijink, Arthur; Bestmann, Sven; Rothwell, John C.

    2013-01-01

    Action selection describes the high-level process which selects between competing movements. In animals, behavioural variability is critical for the motor exploration required to select the action which optimizes reward and minimizes cost/punishment, and is guided by dopamine (DA). The aim of this study was to test in humans whether low-level movement parameters are affected by punishment and reward in ways similar to high-level action selection. Moreover, we addressed the proposed dependence of behavioural and neurophysiological variability on DA, and whether this may underpin the exploration of kinematic parameters. Participants performed an out-and-back index finger movement and were instructed that monetary reward and punishment were based on its maximal acceleration (MA). In fact, the feedback was not contingent on the participant’s behaviour but pre-determined. Blocks highly-biased towards punishment were associated with increased MA variability relative to blocks with either reward or without feedback. This increase in behavioural variability was positively correlated with neurophysiological variability, as measured by changes in cortico-spinal excitability with transcranial magnetic stimulation over the primary motor cortex. Following the administration of a DA-antagonist, the variability associated with punishment diminished and the correlation between behavioural and neurophysiological variability no longer existed. Similar changes in variability were not observed when participants executed a pre-determined MA, nor did DA influence resting neurophysiological variability. Thus, under conditions of punishment, DA-dependent processes influence the selection of low-level movement parameters. We propose that the enhanced behavioural variability reflects the exploration of kinematic parameters for less punishing, or conversely more rewarding, outcomes. PMID:23447607

  15. Central limit theorem for the Banach-valued weakly dependent random variables

    International Nuclear Information System (INIS)

    Dmitrovskij, V.A.; Ermakov, S.V.; Ostrovskij, E.I.

    1983-01-01

    The central limit theorem (CLT) for the Banach-valued weakly dependent random variables is proved. In proving CLT convergence of finite-measured (i.e. cylindrical) distributions is established. A weak compactness of the family of measures generated by a certain sequence is confirmed. The continuity of the limiting field is checked

  16. Construction of adjoint operators for coupled equations depending on different variables

    International Nuclear Information System (INIS)

    Hoogenboom, J.E.

    1986-01-01

    A procedure is described for the construction of the adjoint operator matrix in case of coupled equations defining quantities that depend on different sets of variables. This case is not properly treated in the literature. From this procedure a simple rule can be deduced for the construction of such adjoint operator matrices

  17. Effects of Variable Production Rate and Time-Dependent Holding Cost for Complementary Products in Supply Chain Model

    Directory of Open Access Journals (Sweden)

    Mitali Sarkar

    2017-01-01

    Full Text Available Recently, a major trend is going to redesign a production system by controlling or making variable the production rate within some fixed interval to maintain the optimal level. This strategy is more effective when the holding cost is time-dependent as it is interrelated with holding duration of products and rate of production. An effort is made to make a supply chain model (SCM to show the joint effect of variable production rate and time-varying holding cost for specific type of complementary products, where those products are made by two different manufacturers and a common retailer makes them bundle and sells bundles to end customers. Demand of each product is specified by stochastic reservation prices with a known potential market size. Those players of the SCM are considered with unequal power. Stackelberg game approach is employed to obtain global optimum solution of the model. An illustrative numerical example, graphical representation, and managerial insights are given to illustrate the model. Results prove that variable production rate and time-dependent holding cost save more than existing literature.

  18. LHCb time-dependent results

    OpenAIRE

    Calvi, Marta

    2011-01-01

    This review reports preliminary results of time-dependent measurements of decays of $B^0$ mesons and $B^0_s$ mesons coming from the analysis of about 36 pb$^{-1}$ of data collected by the LHCb experiment during the 2010 run of the Large Hadron Collider at $\\sqrt{s}$ = 7 TeV.

  19. LHCb time-dependent results

    OpenAIRE

    Calvi, Marta; Collaboration, for the LHCb

    2011-01-01

    This review reports preliminary results of time-dependent measurements of decays of B^0 mesons and B^0_s mesons coming from the analysis of about 36 pb^-1 of data collected by the LHCb experiment during the 2010 run of the Large Hadron Collider at sqrt(s)=7 TeV.

  20. Population and prehistory III: food-dependent demography in variable environments.

    Science.gov (United States)

    Lee, Charlotte T; Puleston, Cedric O; Tuljapurkar, Shripad

    2009-11-01

    The population dynamics of preindustrial societies depend intimately on their surroundings, and food is a primary means through which environment influences population size and individual well-being. Food production requires labor; thus, dependence of survival and fertility on food involves dependence of a population's future on its current state. We use a perturbation approach to analyze the effects of random environmental variation on this nonlinear, age-structured system. We show that in expanding populations, direct environmental effects dominate induced population fluctuations, so environmental variability has little effect on mean hunger levels, although it does decrease population growth. The growth rate determines the time until population is limited by space. This limitation introduces a tradeoff between population density and well-being, so population effects become more important than the direct effects of the environment: environmental fluctuation increases mortality, releasing density dependence and raising average well-being for survivors. We discuss the social implications of these findings for the long-term fate of populations as they transition from expansion into limitation, given that conditions leading to high well-being during growth depress well-being during limitation.

  1. Variables predicting elevated portal pressure in alcoholic liver disease. Results of a multivariate analysis

    DEFF Research Database (Denmark)

    Krogsgaard, K; Christensen, E; Gluud, C

    1987-01-01

    In 46 alcoholic patients the association of wedged-to-free hepatic-vein pressure with other variables (clinical, histologic, hemodynamic, and liver function data) was studied by means of multiple regression analysis, taking the wedged-to-free hepatic-vein pressure as the dependent variable. Four ...

  2. Tracing the accretion history of supermassive black holes through X-ray variability: results from the ChandraDeep Field-South

    Science.gov (United States)

    Paolillo, M.; Papadakis, I.; Brandt, W. N.; Luo, B.; Xue, Y. Q.; Tozzi, P.; Shemmer, O.; Allevato, V.; Bauer, F. E.; Comastri, A.; Gilli, R.; Koekemoer, A. M.; Liu, T.; Vignali, C.; Vito, F.; Yang, G.; Wang, J. X.; Zheng, X. C.

    2017-11-01

    We study the X-ray variability properties of distant active galactic nuclei (AGNs) in the ChandraDeep Field-South region over 17 yr, up to z ˜ 4, and compare them with those predicted by models based on local samples. We use the results of Monte Carlo simulations to account for the biases introduced by the discontinuous sampling and the low-count regime. We confirm that variability is a ubiquitous property of AGNs, with no clear dependence on the density of the environment. The variability properties of high-z AGNs, over different temporal time-scales, are most consistent with a power spectral density (PSD) described by a broken (or bending) power law, similar to nearby AGNs. We confirm the presence of an anticorrelation between luminosity and variability, resulting from the dependence of variability on black hole (BH) mass and accretion rate. We explore different models, finding that our acceptable solutions predict that BH mass influences the value of the PSD break frequency, while the Eddington ratio λEdd affects the PSD break frequency and, possibly, the PSD amplitude as well. We derive the evolution of the average λEdd as a function of redshift, finding results in agreement with measurements based on different estimators. The large statistical uncertainties make our results consistent with a constant Eddington ratio, although one of our models suggest a possible increase of λEdd with lookback time up to z ˜ 2-3. We conclude that variability is a viable mean to trace the accretion history of supermassive BHs, whose usefulness will increase with future, wide-field/large effective area X-ray missions.

  3. Exercise training improves heart rate variability after methamphetamine dependency.

    Science.gov (United States)

    Dolezal, Brett Andrew; Chudzynski, Joy; Dickerson, Daniel; Mooney, Larissa; Rawson, Richard A; Garfinkel, Alan; Cooper, Christopher B

    2014-06-01

    Heart rate variability (HRV) reflects a healthy autonomic nervous system and is increased with physical training. Methamphetamine dependence (MD) causes autonomic dysfunction and diminished HRV. We compared recently abstinent methamphetamine-dependent participants with age-matched, drug-free controls (DF) and also investigated whether HRV can be improved with exercise training in the methamphetamine-dependent participants. In 50 participants (MD = 28; DF = 22), resting heart rate (HR; R-R intervals) was recorded over 5 min while seated using a monitor affixed to a chest strap. Previously reported time domain (SDNN, RMSSD, pNN50) and frequency domain (LFnu, HFnu, LF/HF) parameters of HRV were calculated with customized software. MD were randomized to thrice-weekly exercise training (ME = 14) or equal attention without training (MC = 14) over 8 wk. Groups were compared using paired and unpaired t-tests. Statistical significance was set at P ≤ 0.05. Participant characteristics were matched between groups (mean ± SD): age = 33 ± 6 yr; body mass = 82.7 ± 12 kg, body mass index = 26.8 ± 4.1 kg·min. Compared with DF, the MD group had significantly higher resting HR (P HRV indices were similar between ME and MC groups. However, after training, the ME group significantly (all P HRV, based on several conventional indices, was diminished in recently abstinent, methamphetamine-dependent individuals. Moreover, physical training yielded a marked increase in HRV, representing increased vagal modulation or improved autonomic balance.

  4. Distance and Azimuthal Dependence of Ground‐Motion Variability for Unilateral Strike‐Slip Ruptures

    KAUST Repository

    Vyas, Jagdish Chandra

    2016-06-21

    We investigate near‐field ground‐motion variability by computing the seismic wavefield for five kinematic unilateral‐rupture models of the 1992 Mw 7.3 Landers earthquake, eight simplified unilateral‐rupture models based on the Landers event, and a large Mw 7.8 ShakeOut scenario. We include the geometrical fault complexity and consider different 1D velocity–density profiles for the Landers simulations and a 3D heterogeneous Earth structure for the ShakeOut scenario. For the Landers earthquake, the computed waveforms are validated using strong‐motion recordings. We analyze the simulated ground‐motion data set in terms of distance and azimuth dependence of peak ground velocity (PGV). Our simulations reveal that intraevent ground‐motion variability Graphic is higher in close distances to the fault (<20  km) and decreases with increasing distance following a power law. This finding is in stark contrast to constant sigma‐values used in empirical ground‐motion prediction equations. The physical explanation of a large near‐field Graphic is the presence of strong directivity and rupture complexity. High values of Graphic occur in the rupture‐propagation direction, but small values occur in the direction perpendicular to it. We observe that the power‐law decay of Graphic is primarily controlled by slip heterogeneity. In addition, Graphic, as function of azimuth, is sensitive to variations in both rupture speed and slip heterogeneity. The azimuth dependence of the ground‐motion mean μln(PGV) is well described by a Cauchy–Lorentz function that provides a novel empirical quantification to model the spatial dependency of ground motion. Online Material: Figures of slip distributions, residuals to ground‐motion prediction equations (GMPEs), distance and azimuthal dependence, and directivity predictor of ground‐motion variability for different source models.

  5. Human Performance Technology (HPT): An Examination of Definitions through Dependent and Independent Variables.

    Science.gov (United States)

    Irlbeck, Sonja A.

    2002-01-01

    Provides a chronological perspective of human performance technology (HPT) definitions and an evaluation of them in terms of independent and dependent variables. Discusses human competence and performance technology and compares the definitions with the goals that have been articulated for HPT. (Author/LRW)

  6. Statistical analysis of nuclear power plant pump failure rate variability: some preliminary results

    International Nuclear Information System (INIS)

    Martz, H.F.; Whiteman, D.E.

    1984-02-01

    In-Plant Reliability Data System (IPRDS) pump failure data on over 60 selected pumps in four nuclear power plants are statistically analyzed using the Failure Rate Analysis Code (FRAC). A major purpose of the analysis is to determine which environmental, system, and operating factors adequately explain the variability in the failure data. Catastrophic, degraded, and incipient failure severity categories are considered for both demand-related and time-dependent failures. For catastrophic demand-related pump failures, the variability is explained by the following factors listed in their order of importance: system application, pump driver, operating mode, reactor type, pump type, and unidentified plant-specific influences. Quantitative failure rate adjustments are provided for the effects of these factors. In the case of catastrophic time-dependent pump failures, the failure rate variability is explained by three factors: reactor type, pump driver, and unidentified plant-specific influences. Finally, point and confidence interval failure rate estimates are provided for each selected pump by considering the influential factors. Both types of estimates represent an improvement over the estimates computed exclusively from the data on each pump

  7. TWO MEASURES OF THE DEPENDENCE OF PREFERENTIAL RANKINGS ON CATEGORICAL VARIABLES

    Directory of Open Access Journals (Sweden)

    Lissowski Grzegorz

    2017-06-01

    Full Text Available The aim of this paper is to apply a general methodology for constructing statistical methods, which is based on decision theory, to give a statistical description of preferential rankings, with a focus on the rankings’ dependence on categorical variables. In the paper, I use functions of description errors that are based on the Kemeny and Hamming distances between preferential orderings, but the proposed methodology can also be applied to other methods of estimating description errors.

  8. Time-dependence in relativistic collisionless shocks: theory of the variable

    Energy Technology Data Exchange (ETDEWEB)

    Spitkovsky, A

    2004-02-05

    We describe results from time-dependent numerical modeling of the collisionless reverse shock terminating the pulsar wind in the Crab Nebula. We treat the upstream relativistic wind as composed of ions and electron-positron plasma embedded in a toroidal magnetic field, flowing radially outward from the pulsar in a sector around the rotational equator. The relativistic cyclotron instability of the ion gyrational orbit downstream of the leading shock in the electron-positron pairs launches outward propagating magnetosonic waves. Because of the fresh supply of ions crossing the shock, this time-dependent process achieves a limit-cycle, in which the waves are launched with periodicity on the order of the ion Larmor time. Compressions in the magnetic field and pair density associated with these waves, as well as their propagation speed, semi-quantitatively reproduce the behavior of the wisp and ring features described in recent observations obtained using the Hubble Space Telescope and the Chandra X-Ray Observatory. By selecting the parameters of the ion orbits to fit the spatial separation of the wisps, we predict the period of time variability of the wisps that is consistent with the data. When coupled with a mechanism for non-thermal acceleration of the pairs, the compressions in the magnetic field and plasma density associated with the optical wisp structure naturally account for the location of X-ray features in the Crab. We also discuss the origin of the high energy ions and their acceleration in the equatorial current sheet of the pulsar wind.

  9. Chaos resulting from nonlinear relations between different variables

    International Nuclear Information System (INIS)

    Dohtani, Akitaka

    2011-01-01

    Research highlights: → We prove a general result on the existence of chaos. → We focus on the cyclic composites of interdependent relations between different variables. → By considering several examples, we conclude that the cyclic composites play an important role in detecting chaotic dynamics. - Abstract: In this study, we further develop the perturbation method of Marotto and investigate the general mechanisms responsible for nonlinear dynamics, which are typical of multidimensional systems. We focus on the composites of interdependent relations between different variables. First, we prove a general result on chaos, which shows that the cyclic composites of nonlinear interdependent relations are sources of chaotic dynamics in multidimensional systems. By considering several examples, we conclude that the cyclic composites play an important role in detecting chaotic dynamics.

  10. Panel data models extended to spatial error autocorrelation or a spatially lagged dependent variable

    NARCIS (Netherlands)

    Elhorst, J. Paul

    2001-01-01

    This paper surveys panel data models extended to spatial error autocorrelation or a spatially lagged dependent variable. In particular, it focuses on the specification and estimation of four panel data models commonly used in applied research: the fixed effects model, the random effects model, the

  11. BAYESIAN TECHNIQUES FOR COMPARING TIME-DEPENDENT GRMHD SIMULATIONS TO VARIABLE EVENT HORIZON TELESCOPE OBSERVATIONS

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Junhan; Marrone, Daniel P.; Chan, Chi-Kwan; Medeiros, Lia; Özel, Feryal; Psaltis, Dimitrios, E-mail: junhankim@email.arizona.edu [Department of Astronomy and Steward Observatory, University of Arizona, 933 N. Cherry Avenue, Tucson, AZ 85721 (United States)

    2016-12-01

    The Event Horizon Telescope (EHT) is a millimeter-wavelength, very-long-baseline interferometry (VLBI) experiment that is capable of observing black holes with horizon-scale resolution. Early observations have revealed variable horizon-scale emission in the Galactic Center black hole, Sagittarius A* (Sgr A*). Comparing such observations to time-dependent general relativistic magnetohydrodynamic (GRMHD) simulations requires statistical tools that explicitly consider the variability in both the data and the models. We develop here a Bayesian method to compare time-resolved simulation images to variable VLBI data, in order to infer model parameters and perform model comparisons. We use mock EHT data based on GRMHD simulations to explore the robustness of this Bayesian method and contrast it to approaches that do not consider the effects of variability. We find that time-independent models lead to offset values of the inferred parameters with artificially reduced uncertainties. Moreover, neglecting the variability in the data and the models often leads to erroneous model selections. We finally apply our method to the early EHT data on Sgr A*.

  12. Variability of creatinine measurements in clinical laboratories: results from the CRIC study.

    Science.gov (United States)

    Joffe, Marshall; Hsu, Chi-yuan; Feldman, Harold I; Weir, Matthew; Landis, J R; Hamm, L Lee

    2010-01-01

    Estimating equations using serum creatinine (SCr) are often used to assess glomerular filtration rate (GFR). Such creatinine (Cr)-based formulae may produce biased estimates of GFR when using Cr measurements that have not been calibrated to reference laboratories. In this paper, we sought to examine the degree of this variation in Cr assays in several laboratories associated with academic medical centers affiliated with the Chronic Renal Insufficiency Cohort (CRIC) Study; to consider how best to correct for this variation, and to quantify the impact of such corrections on eligibility for participation in CRIC. Variability of Cr is of particular concern in the conduct of CRIC, a large multicenter study of subjects with chronic renal disease, because eligibility for the study depends on Cr-based assessment of GFR. A library of 5 large volume plasma specimens from apheresis patients was assembled, representing levels of plasma Cr from 0.8 to 2.4 mg/dl. Samples from this library were used for measurement of Cr at each of the 14 CRIC laboratories repetitively over time. We used graphical displays and linear regression methods to examine the variability in Cr, and used linear regression to develop calibration equations. We also examined the impact of the various calibration equations on the proportion of subjects screened as potential participants who were actually eligible for the study. There was substantial variability in Cr assays across laboratories and over time. We developed calibration equations for each laboratory; these equations varied substantially among laboratories and somewhat over time in some laboratories. The laboratory site contributed the most to variability (51% of the variance unexplained by the specimen) and variation with time accounted for another 15%. In some laboratories, calibration equations resulted in differences in eligibility for CRIC of as much as 20%. The substantial variability in SCr assays across laboratories necessitates calibration

  13. THE TIME DOMAIN SPECTROSCOPIC SURVEY: VARIABLE SELECTION AND ANTICIPATED RESULTS

    Energy Technology Data Exchange (ETDEWEB)

    Morganson, Eric; Green, Paul J. [Harvard Smithsonian Center for Astrophysics, 60 Garden St, Cambridge, MA 02138 (United States); Anderson, Scott F.; Ruan, John J. [Department of Astronomy, University of Washington, Box 351580, Seattle, WA 98195 (United States); Myers, Adam D. [Department of Physics and Astronomy, University of Wyoming, Laramie, WY 82071 (United States); Eracleous, Michael; Brandt, William Nielsen [Department of Astronomy and Astrophysics, 525 Davey Laboratory, The Pennsylvania State University, University Park, PA 16802 (United States); Kelly, Brandon [Department of Physics, Broida Hall, University of California, Santa Barbara, CA 93106-9530 (United States); Badenes, Carlos [Department of Physics and Astronomy and Pittsburgh Particle Physics, Astrophysics and Cosmology Center (PITT PACC), University of Pittsburgh, 3941 O’Hara St, Pittsburgh, PA 15260 (United States); Bañados, Eduardo [Max-Planck-Institut für Astronomie, Königstuhl 17, D-69117 Heidelberg (Germany); Blanton, Michael R. [Center for Cosmology and Particle Physics, Department of Physics, New York University, 4 Washington Place, New York, NY 10003 (United States); Bershady, Matthew A. [Department of Astronomy, University of Wisconsin, 475 N. Charter St., Madison, WI 53706 (United States); Borissova, Jura [Instituto de Física y Astronomía, Universidad de Valparaíso, Av. Gran Bretaña 1111, Playa Ancha, Casilla 5030, and Millennium Institute of Astrophysics (MAS), Santiago (Chile); Burgett, William S. [GMTO Corp, Suite 300, 251 S. Lake Ave, Pasadena, CA 91101 (United States); Chambers, Kenneth, E-mail: emorganson@cfa.harvard.edu [Institute for Astronomy, University of Hawaii at Manoa, Honolulu, HI 96822 (United States); and others

    2015-06-20

    We present the selection algorithm and anticipated results for the Time Domain Spectroscopic Survey (TDSS). TDSS is an Sloan Digital Sky Survey (SDSS)-IV Extended Baryon Oscillation Spectroscopic Survey (eBOSS) subproject that will provide initial identification spectra of approximately 220,000 luminosity-variable objects (variable stars and active galactic nuclei across 7500 deg{sup 2} selected from a combination of SDSS and multi-epoch Pan-STARRS1 photometry. TDSS will be the largest spectroscopic survey to explicitly target variable objects, avoiding pre-selection on the basis of colors or detailed modeling of specific variability characteristics. Kernel Density Estimate analysis of our target population performed on SDSS Stripe 82 data suggests our target sample will be 95% pure (meaning 95% of objects we select have genuine luminosity variability of a few magnitudes or more). Our final spectroscopic sample will contain roughly 135,000 quasars and 85,000 stellar variables, approximately 4000 of which will be RR Lyrae stars which may be used as outer Milky Way probes. The variability-selected quasar population has a smoother redshift distribution than a color-selected sample, and variability measurements similar to those we develop here may be used to make more uniform quasar samples in large surveys. The stellar variable targets are distributed fairly uniformly across color space, indicating that TDSS will obtain spectra for a wide variety of stellar variables including pulsating variables, stars with significant chromospheric activity, cataclysmic variables, and eclipsing binaries. TDSS will serve as a pathfinder mission to identify and characterize the multitude of variable objects that will be detected photometrically in even larger variability surveys such as Large Synoptic Survey Telescope.

  14. Uncovering state-dependent relationships in shallow lakes using Bayesian latent variable regression.

    Science.gov (United States)

    Vitense, Kelsey; Hanson, Mark A; Herwig, Brian R; Zimmer, Kyle D; Fieberg, John

    2018-03-01

    Ecosystems sometimes undergo dramatic shifts between contrasting regimes. Shallow lakes, for instance, can transition between two alternative stable states: a clear state dominated by submerged aquatic vegetation and a turbid state dominated by phytoplankton. Theoretical models suggest that critical nutrient thresholds differentiate three lake types: highly resilient clear lakes, lakes that may switch between clear and turbid states following perturbations, and highly resilient turbid lakes. For effective and efficient management of shallow lakes and other systems, managers need tools to identify critical thresholds and state-dependent relationships between driving variables and key system features. Using shallow lakes as a model system for which alternative stable states have been demonstrated, we developed an integrated framework using Bayesian latent variable regression (BLR) to classify lake states, identify critical total phosphorus (TP) thresholds, and estimate steady state relationships between TP and chlorophyll a (chl a) using cross-sectional data. We evaluated the method using data simulated from a stochastic differential equation model and compared its performance to k-means clustering with regression (KMR). We also applied the framework to data comprising 130 shallow lakes. For simulated data sets, BLR had high state classification rates (median/mean accuracy >97%) and accurately estimated TP thresholds and state-dependent TP-chl a relationships. Classification and estimation improved with increasing sample size and decreasing noise levels. Compared to KMR, BLR had higher classification rates and better approximated the TP-chl a steady state relationships and TP thresholds. We fit the BLR model to three different years of empirical shallow lake data, and managers can use the estimated bifurcation diagrams to prioritize lakes for management according to their proximity to thresholds and chance of successful rehabilitation. Our model improves upon

  15. A variable-order time-dependent neutron transport method for nuclear reactor kinetics using analytically-integrated space-time characteristics

    International Nuclear Information System (INIS)

    Hoffman, A. J.; Lee, J. C.

    2013-01-01

    A new time-dependent neutron transport method based on the method of characteristics (MOC) has been developed. Whereas most spatial kinetics methods treat time dependence through temporal discretization, this new method treats time dependence by defining the characteristics to span space and time. In this implementation regions are defined in space-time where the thickness of the region in time fulfills an analogous role to the time step in discretized methods. The time dependence of the local source is approximated using a truncated Taylor series expansion with high order derivatives approximated using backward differences, permitting the solution of the resulting space-time characteristic equation. To avoid a drastic increase in computational expense and memory requirements due to solving many discrete characteristics in the space-time planes, the temporal variation of the boundary source is similarly approximated. This allows the characteristics in the space-time plane to be represented analytically rather than discretely, resulting in an algorithm comparable in implementation and expense to one that arises from conventional time integration techniques. Furthermore, by defining the boundary flux time derivative in terms of the preceding local source time derivative and boundary flux time derivative, the need to store angularly-dependent data is avoided without approximating the angular dependence of the angular flux time derivative. The accuracy of this method is assessed through implementation in the neutron transport code DeCART. The method is employed with variable-order local source representation to model a TWIGL transient. The results demonstrate that this method is accurate and more efficient than the discretized method. (authors)

  16. Variability of interconnected wind plants: correlation length and its dependence on variability time scale

    Science.gov (United States)

    St. Martin, Clara M.; Lundquist, Julie K.; Handschy, Mark A.

    2015-04-01

    The variability in wind-generated electricity complicates the integration of this electricity into the electrical grid. This challenge steepens as the percentage of renewably-generated electricity on the grid grows, but variability can be reduced by exploiting geographic diversity: correlations between wind farms decrease as the separation between wind farms increases. But how far is far enough to reduce variability? Grid management requires balancing production on various timescales, and so consideration of correlations reflective of those timescales can guide the appropriate spatial scales of geographic diversity grid integration. To answer ‘how far is far enough,’ we investigate the universal behavior of geographic diversity by exploring wind-speed correlations using three extensive datasets spanning continents, durations and time resolution. First, one year of five-minute wind power generation data from 29 wind farms span 1270 km across Southeastern Australia (Australian Energy Market Operator). Second, 45 years of hourly 10 m wind-speeds from 117 stations span 5000 km across Canada (National Climate Data Archive of Environment Canada). Finally, four years of five-minute wind-speeds from 14 meteorological towers span 350 km of the Northwestern US (Bonneville Power Administration). After removing diurnal cycles and seasonal trends from all datasets, we investigate dependence of correlation length on time scale by digitally high-pass filtering the data on 0.25-2000 h timescales and calculating correlations between sites for each high-pass filter cut-off. Correlations fall to zero with increasing station separation distance, but the characteristic correlation length varies with the high-pass filter applied: the higher the cut-off frequency, the smaller the station separation required to achieve de-correlation. Remarkable similarities between these three datasets reveal behavior that, if universal, could be particularly useful for grid management. For high

  17. Method of nuclear reactor control using a variable temperature load dependent set point

    International Nuclear Information System (INIS)

    Kelly, J.J.; Rambo, G.E.

    1982-01-01

    A method and apparatus for controlling a nuclear reactor in response to a variable average reactor coolant temperature set point is disclosed. The set point is dependent upon percent of full power load demand. A manually-actuated ''droop mode'' of control is provided whereby the reactor coolant temperature is allowed to drop below the set point temperature a predetermined amount wherein the control is switched from reactor control rods exclusively to feedwater flow

  18. Maximal Inequalities for Dependent Random Variables

    DEFF Research Database (Denmark)

    Hoffmann-Jorgensen, Jorgen

    2016-01-01

    Maximal inequalities play a crucial role in many probabilistic limit theorem; for instance, the law of large numbers, the law of the iterated logarithm, the martingale limit theorem and the central limit theorem. Let X-1, X-2,... be random variables with partial sums S-k = X-1 + ... + X-k. Then a......Maximal inequalities play a crucial role in many probabilistic limit theorem; for instance, the law of large numbers, the law of the iterated logarithm, the martingale limit theorem and the central limit theorem. Let X-1, X-2,... be random variables with partial sums S-k = X-1 + ... + X......-k. Then a maximal inequality gives conditions ensuring that the maximal partial sum M-n = max(1) (...

  19. The Attentional Dependence of Emotion Cognition is Variable with the Competing Task

    Directory of Open Access Journals (Sweden)

    Cheng Chen

    2016-11-01

    Full Text Available The relationship between emotion and attention has fascinated researchers for decades. Many previous studies have used eye-tracking, ERP, MEG and fMRI to explore this issue but have reached different conclusions: some researchers hold that emotion cognition is an automatic process and independent of attention, while some others believed that emotion cognition is modulated by attentional resources and is a type of controlled processing. The present research aimed to investigate this controversy, and we hypothesized that the attentional dependence of emotion cognition is variable with the competing task. Eye-tracking technology and a dual-task paradigm were adopted, and subjects’ attention was manipulated to fixate at the central task to investigate whether subjects could detect the emotional faces presented in the peripheral area with a decrease or near-absence of attention. The results revealed that when the peripheral task was emotional face discrimination but the central attention-demanding task was different, subjects performed well in the peripheral task, which means that emotional information can be processed in parallel with other stimuli, and there may be a specific channel in the human brain for processing emotional information. However, when the central and peripheral tasks were both emotional face discrimination, subjects could not perform well in the peripheral task, indicating that the processing of emotional information required attentional resources and that it is a type of controlled processing. Therefore, we concluded that the attentional dependence of emotion cognition varied with the competing task.

  20. Resistor capacitor, primitive variable solution of buoyant fluid flow within an enclosure with highly temperature dependent viscosity

    Energy Technology Data Exchange (ETDEWEB)

    Burns, S.P. [Texas Univ., Austin, TX (United States); Gianoulakis, S.E. [Sandia National Labs., Albuquerque, NM (United States)

    1995-07-01

    A numerical solution for buoyant natural convection within a square enclosure containing a fluid with highly temperature dependent viscosity is presented. Although the fluid properties employed do not represent any real fluid, the large variation in the fluid viscosity with temperature is characteristic of turbulent flow modeling with eddy-viscosity concepts. Results are obtained using a primitive variable formulation and the resistor method. The results presented include velocity, temperature and pressure distributions within the enclosure as well as shear stress and heat flux distributions along the enclosure walls. Three mesh refinements were employed and uncertainty values are suggested for the final mesh refinement. These solutions are part of a contributed benchmark solution set for the subject problem.

  1. The dependence of J/ψ-nucleon inelastic cross section on the Feynman variable

    International Nuclear Information System (INIS)

    Duan Chungui; Liu Na; Miao Wendan

    2011-01-01

    By means of two typical sets of nuclear parton distribution functions, meanwhile taking account of the energy loss of the beam proton and the nuclear absorption of the charmonium states traversing the nuclear matter in the uniform framework of the Glauber model, a leading order phenomenological analysis is given in the color evaporation model of the E866 experimental data on J/ψ production differential cross section ratios R Fe/Be (x F ). It is shown that the energy loss effect of beam proton on R Fe/Be (x F ) is more important than the nuclear effects on parton distribution functions in the high Feynman variable x F region. It is found that the J/ψ-nucleon inelastic cross section depends on the Feynman variable x F and increases linearly with x F in the region x F > 0.2. (authors)

  2. Degree of multicollinearity and variables involved in linear dependence in additive-dominant models

    Directory of Open Access Journals (Sweden)

    Juliana Petrini

    2012-12-01

    Full Text Available The objective of this work was to assess the degree of multicollinearity and to identify the variables involved in linear dependence relations in additive-dominant models. Data of birth weight (n=141,567, yearling weight (n=58,124, and scrotal circumference (n=20,371 of Montana Tropical composite cattle were used. Diagnosis of multicollinearity was based on the variance inflation factor (VIF and on the evaluation of the condition indexes and eigenvalues from the correlation matrix among explanatory variables. The first model studied (RM included the fixed effect of dam age class at calving and the covariates associated to the direct and maternal additive and non-additive effects. The second model (R included all the effects of the RM model except the maternal additive effects. Multicollinearity was detected in both models for all traits considered, with VIF values of 1.03 - 70.20 for RM and 1.03 - 60.70 for R. Collinearity increased with the increase of variables in the model and the decrease in the number of observations, and it was classified as weak, with condition index values between 10.00 and 26.77. In general, the variables associated with additive and non-additive effects were involved in multicollinearity, partially due to the natural connection between these covariables as fractions of the biological types in breed composition.

  3. Building the nodal nuclear data dependences in a many-dimensional state-variable space

    International Nuclear Information System (INIS)

    Dufek, Jan

    2011-01-01

    Highlights: → The Abstract and Introduction are revised to reflect reviewers' comments. → Section is revised and simplified. → The third paragraph in Section is revised. → All typos are fixed. - Abstract: We present new methods for building the polynomial-regression based nodal nuclear data models. The data models can reflect dependences on a large number of state variables, and they can consider various history effects. Suitable multivariate polynomials that approximate the nodal data dependences are identified efficiently in an iterative manner. The history effects are analysed using a new sampling scheme for lattice calculations where the traditional base burnup and branch calculations are replaced by a large number of diverse burnup histories. The total number of lattice calculations is controlled so that the data models are built to a required accuracy.

  4. Exact statistical results for binary mixing and reaction in variable density turbulence

    Science.gov (United States)

    Ristorcelli, J. R.

    2017-02-01

    We report a number of rigorous statistical results on binary active scalar mixing in variable density turbulence. The study is motivated by mixing between pure fluids with very different densities and whose density intensity is of order unity. Our primary focus is the derivation of exact mathematical results for mixing in variable density turbulence and we do point out the potential fields of application of the results. A binary one step reaction is invoked to derive a metric to asses the state of mixing. The mean reaction rate in variable density turbulent mixing can be expressed, in closed form, using the first order Favre mean variables and the Reynolds averaged density variance, ⟨ρ2⟩ . We show that the normalized density variance, ⟨ρ2⟩ , reflects the reduction of the reaction due to mixing and is a mix metric. The result is mathematically rigorous. The result is the variable density analog, the normalized mass fraction variance ⟨c2⟩ used in constant density turbulent mixing. As a consequence, we demonstrate that use of the analogous normalized Favre variance of the mass fraction, c″ ⁣2˜ , as a mix metric is not theoretically justified in variable density turbulence. We additionally derive expressions relating various second order moments of the mass fraction, specific volume, and density fields. The central role of the density specific volume covariance ⟨ρ v ⟩ is highlighted; it is a key quantity with considerable dynamical significance linking various second order statistics. For laboratory experiments, we have developed exact relations between the Reynolds scalar variance ⟨c2⟩ its Favre analog c″ ⁣2˜ , and various second moments including ⟨ρ v ⟩ . For moment closure models that evolve ⟨ρ v ⟩ and not ⟨ρ2⟩ , we provide a novel expression for ⟨ρ2⟩ in terms of a rational function of ⟨ρ v ⟩ that avoids recourse to Taylor series methods (which do not converge for large density differences). We have derived

  5. The Relationship of Field Dependent/Independent Cognitive Styles, Stimuli Variability and Time Factor on Student Achievement.

    Science.gov (United States)

    Atang, Christopher I.

    The effects of black and white and color illustrations on student achievement were studied to investigate the relationships between cognitive styles and instructional design. Field dependence (FD) and field independence (FI) were chosen as the cognitive style variables. Subjects were 85 freshman students in the Iowa State University Psychology…

  6. Variability in colonization of arbuscular mycorrhizal fungi and its effect on mycorrhizal dependency of improved and unimproved soybean cultivars.

    Science.gov (United States)

    Salloum, M S; Guzzo, M C; Velazquez, M S; Sagadin, M B; Luna, C M

    2016-12-01

    Breeding selection of germplasm under fertilized conditions may reduce the frequency of genes that promote mycorrhizal associations. This study was developed to compare variability in mycorrhizal colonization and its effect on mycorrhizal dependency (MD) in improved soybean genotypes (I-1 and I-2) with differential tolerance to drought stress, and in unimproved soybean genotypes (UI-3 and UI-4). As inoculum, a mixed native arbuscular mycorrhizal fungi (AMF) was isolated from soybean roots, showing spores mostly of the species Funneliformis mosseae. At 20 days, unimproved genotypes followed by I-2, showed an increase in arbuscule formation, but not in I-1. At 40 days, mycorrhizal plants showed an increase in nodulation, this effect being more evident in unimproved genotypes. Mycorrhizal dependency, evaluated as growth and biochemical parameters from oxidative stress was increased in unimproved and I-2 since 20 days, whereas in I-1, MD increased at 40 days. We cannot distinguish significant differences in AMF colonization and MD between unimproved and I-2. However, variability among improved genotypes was observed. Our results suggest that selection for improved soybean genotypes with good and rapid AMF colonization, particularly high arbuscule/hyphae ratio could be a useful strategy for the development of genotypes that optimize AMF contribution to cropping systems.

  7. Alaskan soil carbon stocks: spatial variability and dependence on environmental factors

    Directory of Open Access Journals (Sweden)

    U. Mishra

    2012-09-01

    Full Text Available The direction and magnitude of soil organic carbon (SOC changes in response to climate change depend on the spatial and vertical distributions of SOC. We estimated spatially resolved SOC stocks from surface to C horizon, distinguishing active-layer and permafrost-layer stocks, based on geospatial analysis of 472 soil profiles and spatially referenced environmental variables for Alaska. Total Alaska state-wide SOC stock was estimated to be 77 Pg, with 61% in the active-layer, 27% in permafrost, and 12% in non-permafrost soils. Prediction accuracy was highest for the active-layer as demonstrated by highest ratio of performance to deviation (1.5. Large spatial variability was predicted, with whole-profile, active-layer, and permafrost-layer stocks ranging from 1–296 kg C m−2, 2–166 kg m−2, and 0–232 kg m−2, respectively. Temperature and soil wetness were found to be primary controllers of whole-profile, active-layer, and permafrost-layer SOC stocks. Secondary controllers, in order of importance, were found to be land cover type, topographic attributes, and bedrock geology. The observed importance of soil wetness rather than precipitation on SOC stocks implies that the poor representation of high-latitude soil wetness in Earth system models may lead to large uncertainty in predicted SOC stocks under future climate change scenarios. Under strict caveats described in the text and assuming temperature changes from the A1B Intergovernmental Panel on Climate Change emissions scenario, our geospatial model indicates that the equilibrium average 2100 Alaska active-layer depth could deepen by 11 cm, resulting in a thawing of 13 Pg C currently in permafrost. The equilibrium SOC loss associated with this warming would be highest under continuous permafrost (31%, followed by discontinuous (28%, isolated (24.3%, and sporadic (23.6% permafrost areas. Our high-resolution mapping of soil carbon stock reveals the

  8. Rapidly variable relatvistic absorption

    Science.gov (United States)

    Parker, M.; Pinto, C.; Fabian, A.; Lohfink, A.; Buisson, D.; Alston, W.; Jiang, J.

    2017-10-01

    I will present results from the 1.5Ms XMM-Newton observing campaign on the most X-ray variable AGN, IRAS 13224-3809. We find a series of nine absorption lines with a velocity of 0.24c from an ultra-fast outflow. For the first time, we are able to see extremely rapid variability of the UFO features, and can link this to the X-ray variability from the inner accretion disk. We find a clear flux dependence of the outflow features, suggesting that the wind is ionized by increasing X-ray emission.

  9. Threshold-dependent variability of coronary artery calcification measurements - implications for contrast-enhanced multi-detector row-computed tomography

    International Nuclear Information System (INIS)

    Moselewski, Fabian; Ferencik, Maros; Achenbach, Stephan; Abbara, Suhny; Cury, Ricardo C.; Booth, Sarah L.; Jang, Ik-Kyung; Brady, Thomas J.; Hoffmann, Udo

    2006-01-01

    Introduction: The present study investigated the threshold-dependent variability of coronary artery calcification (CAC) measurements and the potential to quantify CAC in contrast-enhanced multi-detector row-computed tomography (MDCT). Methods: We compared the mean CT attenuation of CAC to luminal contrast enhancement of the coronary arteries in 30 patients (n = 30) undergoing standard coronary contrast-enhanced spiral MDCT. The modified Agatston score [AS], calcified plaque volume [CV], and mineral mass [MM]) at four different thresholds (130, 200, 300, and 400 HU) were measured in 50 patients who underwent non-contrast-enhanced MDCT. Results: Mean CT attenuation of CAC was similar to the attenuation of the contrast-enhanced coronary lumen (CAC 297.1 ± 68.7 HU versus 295 ± 65 HU (p < 0.0001), respectively). Above a threshold of 300 HU CAC measurements significantly varied to standard measurements obtained at a threshold of 130 HU (p < 0.0001). The threshold-dependent variation of MM measurements was significantly smaller than for AS and CV (130 HU versus 400 HU: 63, 75, and 81, respectively; p < 0.001). These differences resulted in a change of age and gender based percentile category for AS in 78% of subjects. Discussion: We demonstrated that CAC measurements are threshold dependent with MM measurements having significantly less variation than AS or CV. Due to the similarity of mean CT attenuation of CAC and the contrast-enhanced coronary lumen accurate quantification of CAC may be difficult in standard coronary contrast-enhanced spiral MDCT

  10. Threshold-dependent variability of coronary artery calcification measurements - implications for contrast-enhanced multi-detector row-computed tomography

    Energy Technology Data Exchange (ETDEWEB)

    Moselewski, Fabian [Division of Cardiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA (United States); Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA (United States); Ferencik, Maros [Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA (United States); Achenbach, Stephan [Division of Cardiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA (United States); Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA (United States); Department of Internal Medicine II (Cardiology), University of Erlangen (Germany); Abbara, Suhny [Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA (United States); Cury, Ricardo C. [Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA (United States); Booth, Sarah L. [Jean Mayer USDA Human Nutrition Research Center on Aging, 711 Washington St., Boston, MA 02114 (United States); Jang, Ik-Kyung [Division of Cardiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA (United States); Brady, Thomas J. [Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA (United States); Hoffmann, Udo [Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA (United States)]. E-mail: uhoffman@partners.org

    2006-03-15

    Introduction: The present study investigated the threshold-dependent variability of coronary artery calcification (CAC) measurements and the potential to quantify CAC in contrast-enhanced multi-detector row-computed tomography (MDCT). Methods: We compared the mean CT attenuation of CAC to luminal contrast enhancement of the coronary arteries in 30 patients (n = 30) undergoing standard coronary contrast-enhanced spiral MDCT. The modified Agatston score [AS], calcified plaque volume [CV], and mineral mass [MM] at four different thresholds (130, 200, 300, and 400 HU) were measured in 50 patients who underwent non-contrast-enhanced MDCT. Results: Mean CT attenuation of CAC was similar to the attenuation of the contrast-enhanced coronary lumen (CAC 297.1 {+-} 68.7 HU versus 295 {+-} 65 HU (p < 0.0001), respectively). Above a threshold of 300 HU CAC measurements significantly varied to standard measurements obtained at a threshold of 130 HU (p < 0.0001). The threshold-dependent variation of MM measurements was significantly smaller than for AS and CV (130 HU versus 400 HU: 63, 75, and 81, respectively; p < 0.001). These differences resulted in a change of age and gender based percentile category for AS in 78% of subjects. Discussion: We demonstrated that CAC measurements are threshold dependent with MM measurements having significantly less variation than AS or CV. Due to the similarity of mean CT attenuation of CAC and the contrast-enhanced coronary lumen accurate quantification of CAC may be difficult in standard coronary contrast-enhanced spiral MDCT.

  11. Transition Achievement among Young Adults with Deafness: What Variables Relate to Success?

    Science.gov (United States)

    Bullis, Michael; And Others

    1995-01-01

    Examines the transition achievement of deaf persons 3 or 4 years out of high school (n=308). Ten independent variables were used to predict 2 dichotomous dependent variables: engagement with community (56%), and residential status (52% living independently). Results are presented for each dependent variable. (JPS)

  12. The Dependence of Cloud Particle Size on Non-Aerosol-Loading Related Variables

    Energy Technology Data Exchange (ETDEWEB)

    Shao, H.; Liu, G.

    2005-03-18

    An enhanced concentration of aerosol may increase the number of cloud drops by providing more cloud condensation nuclei (CCN), which in turn results in a higher cloud albedo at a constant cloud liquid water path. This process is often referred to as the aerosol indirect effect (AIE). Many in situ and remote sensing observations support this hypothesis (Ramanathan et al. 2001). However, satellite observed relations between aerosol concentration and cloud drop size are not always in agreement with the AIE. Based on global analysis of cloud effective radius (r{sub e}) and aerosol number concentration (N{sub a}) derived from satellite data, Sekiguchi et al. (2003) found that the correlations between the two variables can be either negative, or positive, or none, depending on the location of the clouds. They discovered that significantly negative r{sub e} - N{sub a} correlation can only be identified along coastal regions of the continents where abundant continental aerosols inflow from land, whereas Feingold et al. (2001) found that the response of r{sub e} to aerosol loading is the greatest in the region where aerosol optical depth ({tau}{sub a}) is the smallest. The reason for the discrepancy is likely due to the variations in cloud macroscopic properties such as geometrical thickness (Brenguier et al. 2003). Since r{sub e} is modified not only by aerosol but also by cloud geometrical thickness (H), the correlation between re and {tau}{sub a} actually reflects both the aerosol indirect effect and dependence of H. Therefore, discussing AIE based on the r{sub e}-{tau}{sub a} correlation without taking into account variations in cloud geometrical thickness may be misleading. This paper is motivated to extract aerosols' effect from overall effects using the independent measurements of cloud geometrical thickness, {tau}{sub a} and r{sub e}.

  13. Surfing wave climate variability

    Science.gov (United States)

    Espejo, Antonio; Losada, Iñigo J.; Méndez, Fernando J.

    2014-10-01

    International surfing destinations are highly dependent on specific combinations of wind-wave formation, thermal conditions and local bathymetry. Surf quality depends on a vast number of geophysical variables, and analyses of surf quality require the consideration of the seasonal, interannual and long-term variability of surf conditions on a global scale. A multivariable standardized index based on expert judgment is proposed for this purpose. This index makes it possible to analyze surf conditions objectively over a global domain. A summary of global surf resources based on a new index integrating existing wave, wind, tides and sea surface temperature databases is presented. According to general atmospheric circulation and swell propagation patterns, results show that west-facing low to middle-latitude coasts are more suitable for surfing, especially those in the Southern Hemisphere. Month-to-month analysis reveals strong seasonal variations in the occurrence of surfable events, enhancing the frequency of such events in the North Atlantic and the North Pacific. Interannual variability was investigated by comparing occurrence values with global and regional modes of low-frequency climate variability such as El Niño and the North Atlantic Oscillation, revealing their strong influence at both the global and the regional scale. Results of the long-term trends demonstrate an increase in the probability of surfable events on west-facing coasts around the world in recent years. The resulting maps provide useful information for surfers, the surf tourism industry and surf-related coastal planners and stakeholders.

  14. Memory effects, two color percolation, and the temperature dependence of Mott variable-range hopping

    Science.gov (United States)

    Agam, Oded; Aleiner, Igor L.

    2014-06-01

    There are three basic processes that determine hopping transport: (a) hopping between normally empty sites (i.e., having exponentially small occupation numbers at equilibrium), (b) hopping between normally occupied sites, and (c) transitions between normally occupied and unoccupied sites. In conventional theories all these processes are considered Markovian and the correlations of occupation numbers of different sites are believed to be small (i.e., not exponential in temperature). We show that, contrary to this belief, memory effects suppress the processes of type (c) and manifest themselves in a subleading exponential temperature dependence of the variable-range hopping conductivity. This temperature dependence originates from the property that sites of type (a) and (b) form two independent resistor networks that are weakly coupled to each other by processes of type (c). This leads to a two-color percolation problem which we solve in the critical region.

  15. Motivational and psychological correlates of bodybuilding dependence.

    Science.gov (United States)

    Emini, Neim N; Bond, Malcolm J

    2014-09-01

    Exercise may become physically and psychologically maladaptive if taken to extremes. One example is the dependence reported by some individuals who engage in weight training. The current study explored potential psychological, motivational, emotional and behavioural concomitants of bodybuilding dependence, with a particular focus on motives for weight training. Using a path analysis paradigm, putative causal models sought to explain associations among key study variables. A convenience sample of 101 men aged between 18 and 67 years was assembled from gymnasia in Adelaide, South Australia. Active weight trainers voluntarily completed a questionnaire that included measures of bodybuilding dependence (social dependency, training dependency, and mastery), anger, hostility and aggression, stress and motivations for weight training. Three motives for weight training were identified: mood control, physique anxiety and personal challenge. Of these, personal challenge and mood control were the most directly salient to dependence. Social dependency was particularly relevant to personal challenge, whereas training dependency was associated with both personal challenge and mood control. Mastery demonstrated a direct link with physique anxiety, thus reflecting a unique component of exercise dependence. While it was not possible to determine causality with the available data, the joint roles of variables that influence, or are influenced by, bodybuilding dependence are identified. RESULTS highlight unique motivations for bodybuilding and suggest that dependence could be a result of, and way of coping with, stress manifesting as aggression. A potential framework for future research is provided through the demonstration of plausible causal linkages among these variables.

  16. Demographic models reveal the shape of density dependence for a specialist insect herbivore on variable host plants.

    Science.gov (United States)

    Miller, Tom E X

    2007-07-01

    1. It is widely accepted that density-dependent processes play an important role in most natural populations. However, persistent challenges in our understanding of density-dependent population dynamics include evaluating the shape of the relationship between density and demographic rates (linear, concave, convex), and identifying extrinsic factors that can mediate this relationship. 2. I studied the population dynamics of the cactus bug Narnia pallidicornis on host plants (Opuntia imbricata) that varied naturally in relative reproductive effort (RRE, the proportion of meristems allocated to reproduction), an important plant quality trait. I manipulated per-plant cactus bug densities, quantified subsequent dynamics, and fit stage-structured models to the experimental data to ask if and how density influences demographic parameters. 3. In the field experiment, I found that populations with variable starting densities quickly converged upon similar growth trajectories. In the model-fitting analyses, the data strongly supported a model that defined the juvenile cactus bug retention parameter (joint probability of surviving and not dispersing) as a nonlinear decreasing function of density. The estimated shape of this relationship shifted from concave to convex with increasing host-plant RRE. 4. The results demonstrate that host-plant traits are critical sources of variation in the strength and shape of density dependence in insects, and highlight the utility of integrated experimental-theoretical approaches for identifying processes underlying patterns of change in natural populations.

  17. How to get rid of W: a latent variables approach to modelling spatially lagged variables

    NARCIS (Netherlands)

    Folmer, H.; Oud, J.

    2008-01-01

    In this paper we propose a structural equation model (SEM) with latent variables to model spatial dependence. Rather than using the spatial weights matrix W, we propose to use latent variables to represent spatial dependence and spillover effects, of which the observed spatially lagged variables are

  18. How to get rid of W : a latent variables approach to modelling spatially lagged variables

    NARCIS (Netherlands)

    Folmer, Henk; Oud, Johan

    2008-01-01

    In this paper we propose a structural equation model (SEM) with latent variables to model spatial dependence. Rather than using the spatial weights matrix W, we propose to use latent variables to represent spatial dependence and spillover effects, of which the observed spatially lagged variables are

  19. Variables That Can Affect Student Ratings of Their Professors

    Science.gov (United States)

    Gotlieb, Jerry

    2013-01-01

    Attribution theory was applied to help predict the results of an experiment that examined the effects of three independent variables on students' ratings of their professors. The dependent variables were students' perceptions of whether the professor caused the students' grades and student satisfaction with their professor. The results suggest…

  20. Storm-time ring current: model-dependent results

    Directory of Open Access Journals (Sweden)

    N. Yu. Ganushkina

    2012-01-01

    Full Text Available The main point of the paper is to investigate how much the modeled ring current depends on the representations of magnetic and electric fields and boundary conditions used in simulations. Two storm events, one moderate (SymH minimum of −120 nT on 6–7 November 1997 and one intense (SymH minimum of −230 nT on 21–22 October 1999, are modeled. A rather simple ring current model is employed, namely, the Inner Magnetosphere Particle Transport and Acceleration model (IMPTAM, in order to make the results most evident. Four different magnetic field and two electric field representations and four boundary conditions are used. We find that different combinations of the magnetic and electric field configurations and boundary conditions result in very different modeled ring current, and, therefore, the physical conclusions based on simulation results can differ significantly. A time-dependent boundary outside of 6.6 RE gives a possibility to take into account the particles in the transition region (between dipole and stretched field lines forming partial ring current and near-Earth tail current in that region. Calculating the model SymH* by Biot-Savart's law instead of the widely used Dessler-Parker-Sckopke (DPS relation gives larger and more realistic values, since the currents are calculated in the regions with nondipolar magnetic field. Therefore, the boundary location and the method of SymH* calculation are of key importance for ring current data-model comparisons to be correctly interpreted.

  1. Age dependant somatometric and cephalometric variables among ...

    African Journals Online (AJOL)

    Background: The process of growth passes through stages of developmental processes. This stage is the age. Age is known to affect many parameters in the body and this includes somatometric and cephalometric variables. Methods: The study was conducted with a total number of 409 students of university of Jos, ...

  2. Variability of Surface Reflection Amplitudes of GPR Horn Antenna Depending on Distance between Antenna and Surface

    Directory of Open Access Journals (Sweden)

    Komačka Jozef

    2016-05-01

    Full Text Available The study focused on variability of surface reflections amplitudes of GPR horn antenna in relation to distance between an antenna and a surface is presented in the paper. The air-coupled antenna with the central frequency of 1 GHz was used in the investigation. Four types of surfaces (dry pavement, wet pavement, metal plate and composite layer from gypsum and wood were tested. The distance of antenna above the surfaces was changed in the range from 37.5 cm to 53.5 cm. The amplitudes of negative and positive peaks and their variability were analysed in relation to the distance of antenna above the surfaces. Moreover, the influence of changes in the peaks of negative and positive amplitudes on the total amplitudes was assessed. It was found out the amplitudes of negative peaks for all investigated surfaces were relatively consistent in the range from 40.5 cm to 48.5 cm and the moderate decline was identified in the case of amplitudes of positive peaks in the range of distances from 37.5 cm to 51.5 cm. This decline influences the tendency of total amplitudes. Based on the results of analysis it can be stated the distance of air-coupled antenna above the surface can influence the value of total amplitude and the differences depend on the type of surface.

  3. "Exercise Dependence"--A Problem or Natural Result of High Activity?

    Science.gov (United States)

    Phelan, Suzanne; Bond, Dale S.; Lang, Wei; Jordan, Dustin; Wing, Rena R.

    2011-01-01

    Objectives: To compare physical activity (PA) and exercise dependence (ED) in 267 weight-loss maintainers (WLM) and 213 normal-weight (NW) controls. Methods: PA and ED assessed via accelerometery and the Exercise Dependence Questionnaire. Results: WLM had higher PA levels and ED scores than those of NW (P less than 0.0001). WLM status (P = 0.006)…

  4. NOx emissions from large point sources: variability in ozone production, resulting health damages and economic costs

    International Nuclear Information System (INIS)

    Mauzerall, D.L.; Namsoug Kim

    2005-01-01

    We present a proof-of-concept analysis of the measurement of the health damage of ozone (O 3 ) produced from nitrogen oxides (NO x =NO+NO 2 ) emitted by individual large point sources in the eastern United States. We use a regional atmospheric model of the eastern United States, the Comprehensive Air quality Model with Extensions (CAMx), to quantify the variable impact that a fixed quantity of NO x emitted from individual sources can have on the downwind concentration of surface O 3 , depending on temperature and local biogenic hydrocarbon emissions. We also examine the dependence of resulting O 3 -related health damages on the size of the exposed population. The investigation is relevant to the increasingly widely used 'cap and trade' approach to NO x regulation, which presumes that shifts of emission over time and space, holding the total fixed over the course of the summer O 3 season, will have minimal effect on the environmental outcome. By contrast, we show that a shift of a unit of NO x emissions from one place or time to another could result in large changes in resulting health effects due to O 3 formation and exposure. We indicate how the type of modeling carried out here might be used to attach externality-correcting prices to emissions. Charging emitters fees that are commensurate with the damage caused by their NO x emissions would create an incentive for emitters to reduce emissions at times and in locations where they cause the largest damage. (author)

  5. Solute transport modelling with the variable temporally dependent ...

    Indian Academy of Sciences (India)

    Pintu Das

    2018-02-07

    Feb 7, 2018 ... in a finite domain with time-dependent sources and dis- tance-dependent dispersivities. Also, existing ... solute transport in multi-layered porous media using gen- eralized integral transform technique with .... methods for solving the fractional reaction-–sub-diffusion equation. To solve numerically the Eqs.

  6. Increased variability of bone tissue mineral density resulting from estrogen deficiency influences creep behavior in a rat vertebral body.

    Science.gov (United States)

    Kim, Do-Gyoon; Navalgund, Anand R; Tee, Boon Ching; Noble, Garrett J; Hart, Richard T; Lee, Hye Ri

    2012-11-01

    Progressive vertebral deformation increases the fracture risk of a vertebral body in the postmenopausal patient. Many studies have observed that bone can demonstrate creep behavior, defined as continued time-dependent deformation even when mechanical loading is held constant. Creep is a characteristic of viscoelastic behavior, which is common in biological materials. We hypothesized that estrogen deficiency-dependent alteration of the mineral distribution of bone at the tissue level could influence the progressive postmenopausal vertebral deformity that is observed as the creep response at the organ level. The objective of this study was thus to examine whether the creep behavior of vertebral bone is changed by estrogen deficiency, and to determine which bone property parameters are responsible for the creep response of vertebral bone at physiological loading levels using an ovariectomized (OVX) rat model. Correlations of creep parameters with bone mineral density (BMD), tissue mineral density (TMD) and architectural parameters of both OVX and sham surgery vertebral bone were tested. As the vertebral creep was not fully recovered during the post-creep unloading period, there was substantial residual displacement for both the sham and OVX groups. A strong positive correlation between loading creep and residual displacement was found (r=0.868, pcreep behavior of the OVX group (pcreep caused progressive, permanent reduction in vertebral height for both the sham and OVX groups. In addition, estrogen deficiency-induced active bone remodeling increased variability of trabecular TMD in the OVX group. Taken together, these results suggest that increased variability of trabecular TMD resulting from high bone turnover influences creep behavior of the OVX vertebrae. Copyright © 2012 Elsevier Inc. All rights reserved.

  7. Cataclysmic Variables from SDSS I. The First Results

    OpenAIRE

    Szkody, P.; Anderson, S. F.; Agueros, M.; Covarrubias, R.; Bentz, M.; Hawley, S.; Margon, B.; Voges, W.; Henden, A.; Knapp, G. R.; Berk, D. E. Vanden; Rest, A.; Miknaitis, G.; Magnier, E.; Brinkmann, J.

    2001-01-01

    The commissioning year of the Sloan Digital Sky Survey has demonstrated that many cataclysmic variables have been missed in previous surveys with brighter limits. We report the identification of 22 cataclysmic variables, of which 19 are new discoveries and 3 are known systems (SW UMa, BH Lyn and Vir4). A compendium of positions, colors and characteristics of these systems obtained from the SDSS photometry and spectroscopy is presented along with data obtained during follow-up studies with the...

  8. Strong Laws of Large Numbers for Arrays of Rowwise NA and LNQD Random Variables

    Directory of Open Access Journals (Sweden)

    Jiangfeng Wang

    2011-01-01

    Full Text Available Some strong laws of large numbers and strong convergence properties for arrays of rowwise negatively associated and linearly negative quadrant dependent random variables are obtained. The results obtained not only generalize the result of Hu and Taylor to negatively associated and linearly negative quadrant dependent random variables, but also improve it.

  9. MIRU-VNTR allelic variability depends on Mycobacterium bovis clonal group identity.

    Science.gov (United States)

    Hauer, Amandine; Michelet, Lorraine; De Cruz, Krystel; Cochard, Thierry; Branger, Maxime; Karoui, Claudine; Henault, Sylvie; Biet, Franck; Boschiroli, María Laura

    2016-11-01

    The description of the population of M. bovis strains circulating in France from 1978 to 2013 has highlighted the discriminating power of the MLVA among predominant spoligotype groups. In the present study we aimed to characterize clonal groups via MLVA and to better understand the strain's population structure. MLVA was performed with eight MIRU-VNTR loci, most of them defined by the Venomyc European consortium. The discriminatory index of each MLVA loci was calculated for SB0120, SB0134, SB0121 and the "F4-family", the main spoligotype groups in France. Differences in global DI per spoligotype, but also by locus within each spoligotype, were observed, which strongly suggest the clonal complex nature of these major groups. These MLVA results were compared to those of other European countries where strain collections had been characterized (Spain, Portugal, Italy, Northern Ireland and Belgium). Overall, QUB 3232 and ETR D are respectively the most and the least discriminative loci, regardless of the strains geographical origin. However, marked DI differences are observed in the rest of the MIRU-VNTR loci, again highlighting that strain genetic variability in a country depends on the dominant existing clonal complexes. A web application for M. bovis, including spoligotyping and MIRU-VNTR typing data, was developed to allow inter-laboratory comparison of field isolates. In conclusion, combination of typing methods is required for M. bovis optimum discrimination and differentiation of groups of strains. Thus, the loci employed for MLVA in a country should be those which are the most discriminative for the clonal complexes which characterize their M. bovis population. Copyright © 2016 Elsevier B.V. All rights reserved.

  10. Inference for binomial probability based on dependent Bernoulli random variables with applications to meta‐analysis and group level studies

    Science.gov (United States)

    Bakbergenuly, Ilyas; Morgenthaler, Stephan

    2016-01-01

    We study bias arising as a result of nonlinear transformations of random variables in random or mixed effects models and its effect on inference in group‐level studies or in meta‐analysis. The findings are illustrated on the example of overdispersed binomial distributions, where we demonstrate considerable biases arising from standard log‐odds and arcsine transformations of the estimated probability p^, both for single‐group studies and in combining results from several groups or studies in meta‐analysis. Our simulations confirm that these biases are linear in ρ, for small values of ρ, the intracluster correlation coefficient. These biases do not depend on the sample sizes or the number of studies K in a meta‐analysis and result in abysmal coverage of the combined effect for large K. We also propose bias‐correction for the arcsine transformation. Our simulations demonstrate that this bias‐correction works well for small values of the intraclass correlation. The methods are applied to two examples of meta‐analyses of prevalence. PMID:27192062

  11. The GRB variability/peak luminosity correlation: new results

    International Nuclear Information System (INIS)

    Guidorzi, C.; Rossi, F.; Hurley, K.; Mundell, C.G.

    2005-01-01

    We test the correlation between time variability and isotropic-equivalent peak luminosity found by Reichart et al. (ApJ, 552 (2001) 57) using a set of 26 Gamma-Ray Bursts (GRBs) with known redshift. We confirm the correlation, thought with a larger spread around the best-fit power-law obtained by Reichart et al. which in turn does not provide an acceptable description any longer. In addiction, we find no evidence for correlation between variability and beaming-corrected peak luminosity for a subset of 14 GRBs whose beaming angles have been taken from Ghirlanda et al. (ApJ, 616 (2004) 331). Finally, we investigate the possible connection for some GRBs between the location in the variability/peak luminosity space and some afterglow properties, such as the detectability in the optical band, by adding some GRBs whose redshifts, unknown from direct measurements, have been derived assuming the Amati at al. (AeA, 390 (2002) 81) relationship

  12. Genetical variability of Gladioli as the result of gamma-radiation

    International Nuclear Information System (INIS)

    Jakota, L.I.; Murin, A.V.

    1994-01-01

    In the starting material of Gladioli, got in the result of Y-radiation, the forms with white spots on the petals were observed. The Gladioli form 165-81 is distinguished by low growth and middle early flowering. The flower form is triangular. Basic pigmentation is red. White spots of different size on the petals were observed. The investigation was made in 1992 in the field of genetical variability of Gladioli. The Gladioli form 165-81 was irradiated with gamma-radiation dose 30 Gr. As a result the depression of biometric indicators was observed. Consequently, 30 Gr is a mutant dose for Gladioli

  13. Numerical Solution of the Time-Dependent Navier–Stokes Equation for Variable Density–Variable Viscosity. Part I

    Czech Academy of Sciences Publication Activity Database

    Axelsson, Owe; Xin, H.; Neytcheva, M.

    2015-01-01

    Roč. 20, č. 2 (2015), s. 232-260 ISSN 1392-6292 Institutional support: RVO:68145535 Keywords : variable density * phase-field model * Navier-Stokes equations * preconditioning * variable viscosity Subject RIV: BA - General Mathematics Impact factor: 0.468, year: 2015 http://www.tandfonline.com/doi/abs/10.3846/13926292.2015.1021395

  14. Disaggregating measurement uncertainty from population variability and Bayesian treatment of uncensored results

    International Nuclear Information System (INIS)

    Strom, Daniel J.; Joyce, Kevin E.; Maclellan, Jay A.; Watson, David J.; Lynch, Timothy P.; Antonio, Cheryl L.; Birchall, Alan; Anderson, Kevin K.; Zharov, Peter

    2012-01-01

    In making low-level radioactivity measurements of populations, it is commonly observed that a substantial portion of net results are negative. Furthermore, the observed variance of the measurement results arises from a combination of measurement uncertainty and population variability. This paper presents a method for disaggregating measurement uncertainty from population variability to produce a probability density function (PDF) of possibly true results. To do this, simple, justifiable, and reasonable assumptions are made about the relationship of the measurements to the measurands (the 'true values'). The measurements are assumed to be unbiased, that is, that their average value is the average of the measurands. Using traditional estimates of each measurement's uncertainty to disaggregate population variability from measurement uncertainty, a PDF of measurands for the population is produced. Then, using Bayes's theorem, the same assumptions, and all the data from the population of individuals, a prior PDF is computed for each individual's measurand. These PDFs are non-negative, and their average is equal to the average of the measurement results for the population. The uncertainty in these Bayesian posterior PDFs is all Berkson with no remaining classical component. The methods are applied to baseline bioassay data from the Hanford site. The data include 90Sr urinalysis measurements on 128 people, 137Cs in vivo measurements on 5,337 people, and 239Pu urinalysis measurements on 3,270 people. The method produces excellent results for the 90Sr and 137Cs measurements, since there are nonzero concentrations of these global fallout radionuclides in people who have not been occupationally exposed. The method does not work for the 239Pu measurements in non-occupationally exposed people because the population average is essentially zero.

  15. Monosomy 3 by FISH in uveal melanoma: variability in techniques and results.

    Science.gov (United States)

    Aronow, Mary; Sun, Yang; Saunthararajah, Yogen; Biscotti, Charles; Tubbs, Raymond; Triozzi, Pierre; Singh, Arun D

    2012-09-01

    Tumor monosomy 3 confers a poor prognosis in patients with uveal melanoma. We critically review the techniques used for fluorescence in situ hybridization (FISH) detection of monosomy 3 in order to assess variability in practice patterns and to explain differences in results. Significant variability that has likely affected reported results was found in tissue sampling methods, selection of FISH probes, number of cells counted, and the cut-off point used to determine monosomy 3 status. Clinical parameters and specific techniques employed to report FISH results should be specified so as to allow meta-analysis of published studies. FISH-based detection of monosomy 3 in uveal melanoma has not been performed in a standardized manner, which limits conclusions regarding its clinical utility. FISH is a widely available, versatile technology, and when performed optimally has the potential to be a valuable tool for determining the prognosis of uveal melanoma. Copyright © 2012 Elsevier Inc. All rights reserved.

  16. Establishment of regression dependences. Linear and nonlinear dependences

    International Nuclear Information System (INIS)

    Onishchenko, A.M.

    1994-01-01

    The main problems of determination of linear and 19 types of nonlinear regression dependences are completely discussed. It is taken into consideration that total dispersions are the sum of measurement dispersions and parameter variation dispersions themselves. Approaches to all dispersions determination are described. It is shown that the least square fit gives inconsistent estimation for industrial objects and processes. The correction methods by taking into account comparable measurement errors for both variable give an opportunity to obtain consistent estimation for the regression equation parameters. The condition of the correction technique application expediency is given. The technique for determination of nonlinear regression dependences taking into account the dependence form and comparable errors of both variables is described. 6 refs., 1 tab

  17. Free energy of activation. Definition, properties, and dependent variables with special reference to linear free energy relations

    International Nuclear Information System (INIS)

    Levine, R.D.

    1979-01-01

    The reaction rate constant is expressed as Z exp(-G/sub a//RT). Z is the binary collision frequency. G/sub a/, the free energy of activation, is shown to be the difference between the free energy of the reactive reactants and the free energy of all reactants. The results are derived from both a statistical mechanical and a collision theoretic point of view. While the later is more suitable for an ab-initio computation of the reaction rate, it is the former that lends itself to the search of systematics and of correlations and to compaction of data. Different thermodynamic-like routes to the characterization of G/sub a/ are thus explored. The two most promising ones appear to be the use of thermodynamic type cycles and the changes of dependent variables using the Legendre transform technique. The dependence of G/sub a/ on ΔG 0 , the standard free energy change in the reaction, is examined from the later point of view. It is shown that one can rigorously express this dependence as G/sub a/ = αΔG 0 + G/sub a/ 0 M(α). Here α is the Bronsted slope, α = -par. delta ln k(T)/par. delta(ΔG 0 /RT), G/sub a/ 0 is independent of ΔG 0 and M(α), the Legendre transform of G/sub a/, is a function only of α. For small changes in ΔG 0 , the general result reduces to the familiar ''linear'' free energy relation delta G/sub a/ = α delta ΔG 0 . It is concluded from general considerations that M(α) is a symmetric, convex function of α and hence that α is a monotonically increasing function of ΔG 0 . Experimental data appear to conform well to the form α = 1/[1 + exp(-ΔG 0 /G/sub s/ 0 )]. A simple interpretation of the ΔG 0 dependence of G/sub a/, based on an interpolation of the free energy from that of the reagents to that of the products, is offered. 4 figures, 69 references

  18. Goodness-of-fit tests with dependent observations

    International Nuclear Information System (INIS)

    Chicheportiche, Rémy; Bouchaud, Jean-Philippe

    2011-01-01

    We revisit the Kolmogorov–Smirnov and Cramér–von Mises goodness-of-fit (GoF) tests and propose a generalization to identically distributed, but dependent univariate random variables. We show that the dependence leads to a reduction of the 'effective' number of independent observations. The generalized GoF tests are not distribution-free but rather depend on all the lagged bivariate copulas. These objects, that we call 'self-copulas', encode all the non-linear temporal dependences. We introduce a specific, log-normal model for these self-copulas, for which a number of analytical results are derived. An application to financial time series is provided. As is well known, the dependence is to be long-ranged in this case, a finding that we confirm using self-copulas. As a consequence, the acceptance rates for GoF tests are substantially higher than if the returns were iid random variables

  19. Process depending morphology and resulting physical properties of TPU

    Energy Technology Data Exchange (ETDEWEB)

    Frick, Achim, E-mail: achim.frick@hs-aalen.de; Spadaro, Marcel, E-mail: marcel.spadaro@hs-aalen.de [Institute of Polymer Science and Processing (iPSP), Aalen University (Germany)

    2015-12-17

    Thermoplastic polyurethane (TPU) is a rubber like material with outstanding properties, e.g. for seal applications. TPU basically provides high strength, low frictional behavior and excellent wear resistance. Though, due to segmented structure of TPU, which is composed of hard segments (HSs) and soft segments (SSs), physical properties depend strongly on the morphological arrangement of the phase separated HSs at a certain ratio of HSs to SSs. It is obvious that the TPU deforms differently depending on its bulk morphology. Basically, the morphology can either consist of HSs segregated into small domains, which are well dispersed in the SS matrix or of few strongly phase separated large size HS domains embedded in the SS matrix. The morphology development is hardly ruled by the melt processing conditions of the TPU. Depending on the morphology, TPU provides quite different physical properties with respect to strength, deformation behavior, thermal stability, creep resistance and tribological performance. The paper deals with the influence of important melt processing parameters, such as temperature, pressure and shear conditions, on the resulting physical properties tested by tensile and relaxation experiments. Furthermore the morphology is studied employing differential scanning calorimeter (DSC), transmission light microscopy (TLM), scanning electron beam microscopy (SEM) and transmission electron beam microscopy (TEM) investigations. Correlations between processing conditions and resulting TPU material properties are elaborated. Flow and shear simulations contribute to the understanding of thermal and flow induced morphology development.

  20. Nanostructures study of CNT nanofluids transport with temperature-dependent variable viscosity in a muscular tube

    Science.gov (United States)

    Akbar, Noreen Sher; Abid, Syed Ali; Tripathi, Dharmendra; Mir, Nazir Ahmed

    2017-03-01

    The transport of single-wall carbon nanotube (CNT) nanofluids with temperature-dependent variable viscosity is analyzed by peristaltically driven flow. The main flow problem has been modeled using cylindrical coordinates and flow equations are simplified to ordinary differential equations using long wavelength and low Reynolds' number approximation. Analytical solutions have been obtained for axial velocity, pressure gradient and temperature. Results acquired are discussed graphically for better understanding. It is observed that with an increment in the Grashof number the velocity of the governing fluids starts to decrease significantly and the pressure gradient is higher for pure water as compared to single-walled carbon nanotubes due to low density. As the specific heat is very high for pure water as compared to the multi-wall carbon nanotubes, it raises temperature of the muscles, in the case of pure water, as compared to the multi-walled carbon nanotubes. Furthermore, it is noticed that the trapped bolus starts decreasing in size as the buoyancy forces are dominant as compared to viscous forces. This model may be applicable in biomedical engineering and nanotechnology to design the biomedical devices.

  1. Seasonal Variability in European Radon Measurements

    Science.gov (United States)

    Groves-Kirkby, C. J.; Denman, A. R.; Phillips, P. S.; Crockett, R. G. M.; Sinclair, J. M.

    2009-04-01

    In temperate climates, domestic radon concentration levels are generally seasonally dependent, the level in the home reflecting the convolution of two time-dependent functions. These are the source soil-gas radon concentration itself, and the principal force driving radon into the building from the soil, namely the pressure-difference between interior and exterior environment. While the meteorological influence can be regarded as relatively uniform on a European scale, its variability being defined largely by the influence of North-Atlantic weather systems, soil-gas radon is generally more variable as it is essentially geologically dependent. Seasonal variability of domestic radon concentration can therefore be expected to exhibit geographical variability, as is indeed the case. To compensate for the variability of domestic radon levels when assessing the long term radon health risks, the results of individual short-term measurements are generally converted to equivalent mean annual levels by application of a Seasonal Correction Factor (SCF). This is a multiplying factor, typically derived from measurements of a large number of homes, applied to the measured short-term radon concentration to provide a meaningful annual mean concentration for dose-estimation purposes. Following concern as to the universal applicability of a single SCF set, detailed studies in both the UK and France have reported location-specific SCF sets for different regions of each country. Further results indicate that SCFs applicable to the UK differ significantly from those applicable elsewhere in Europe and North America in both amplitude and phase, supporting the thesis that seasonal variability in indoor radon concentration cannot realistically be compensated for by a single national or international SCF scheme. Published data characterising the seasonal variability of European national domestic radon concentrations, has been collated and analysed, with the objective of identifying

  2. Iterative Strain-Gage Balance Calibration Data Analysis for Extended Independent Variable Sets

    Science.gov (United States)

    Ulbrich, Norbert Manfred

    2011-01-01

    A new method was developed that makes it possible to use an extended set of independent calibration variables for an iterative analysis of wind tunnel strain gage balance calibration data. The new method permits the application of the iterative analysis method whenever the total number of balance loads and other independent calibration variables is greater than the total number of measured strain gage outputs. Iteration equations used by the iterative analysis method have the limitation that the number of independent and dependent variables must match. The new method circumvents this limitation. It simply adds a missing dependent variable to the original data set by using an additional independent variable also as an additional dependent variable. Then, the desired solution of the regression analysis problem can be obtained that fits each gage output as a function of both the original and additional independent calibration variables. The final regression coefficients can be converted to data reduction matrix coefficients because the missing dependent variables were added to the data set without changing the regression analysis result for each gage output. Therefore, the new method still supports the application of the two load iteration equation choices that the iterative method traditionally uses for the prediction of balance loads during a wind tunnel test. An example is discussed in the paper that illustrates the application of the new method to a realistic simulation of temperature dependent calibration data set of a six component balance.

  3. A numerical model for density-and-viscosity-dependent flows in two-dimensional variably saturated porous media

    Science.gov (United States)

    Boufadel, Michel C.; Suidan, Makram T.; Venosa, Albert D.

    1999-04-01

    We present a formulation for water flow and solute transport in two-dimensional variably saturated media that accounts for the effects of the solute on water density and viscosity. The governing equations are cast in a dimensionless form that depends on six dimensionless groups of parameters. These equations are discretized in space using the Galerkin finite element formulation and integrated in time using the backward Euler scheme with mass lumping. The modified Picard method is used to linearize the water flow equation. The resulting numerical model, the MARUN model, is verified by comparison to published numerical results. It is then used to investigate beach hydraulics at seawater concentration (about 30 g l -1) in the context of nutrients delivery for bioremediation of oil spills on beaches. Numerical simulations that we conducted in a rectangular section of a hypothetical beach revealed that buoyancy in the unsaturated zone is significant in soils that are fine textured, with low anisotropy ratio, and/or exhibiting low physical dispersion. In such situations, application of dissolved nutrients to a contaminated beach in a freshwater solution is superior to their application in a seawater solution. Concentration-engendered viscosity effects were negligible with respect to concentration-engendered density effects for the cases that we considered.

  4. Inference for binomial probability based on dependent Bernoulli random variables with applications to meta-analysis and group level studies.

    Science.gov (United States)

    Bakbergenuly, Ilyas; Kulinskaya, Elena; Morgenthaler, Stephan

    2016-07-01

    We study bias arising as a result of nonlinear transformations of random variables in random or mixed effects models and its effect on inference in group-level studies or in meta-analysis. The findings are illustrated on the example of overdispersed binomial distributions, where we demonstrate considerable biases arising from standard log-odds and arcsine transformations of the estimated probability p̂, both for single-group studies and in combining results from several groups or studies in meta-analysis. Our simulations confirm that these biases are linear in ρ, for small values of ρ, the intracluster correlation coefficient. These biases do not depend on the sample sizes or the number of studies K in a meta-analysis and result in abysmal coverage of the combined effect for large K. We also propose bias-correction for the arcsine transformation. Our simulations demonstrate that this bias-correction works well for small values of the intraclass correlation. The methods are applied to two examples of meta-analyses of prevalence. © 2016 The Authors. Biometrical Journal Published by Wiley-VCH Verlag GmbH & Co. KGaA.

  5. Therapeutic effects of ritual ayahuasca use in the treatment of substance dependence--qualitative results.

    Science.gov (United States)

    Loizaga-Velder, Anja; Verres, Rolf

    2014-01-01

    This qualitative empirical study explores the ritual use of ayahuasca in the treatment of addictions. Ayahuasca is an Amazonian psychedelic plant compound created from an admixture of the vine Banisteriopsis caapi and the bush Psychotria viridis. The study included interviews with 13 therapists who apply ayahuasca professionally in the treatment of addictions (four indigenous healers and nine Western mental health professionals with university degrees), two expert researchers, and 14 individuals who had undergone ayahuasca-assisted therapy for addictions in diverse contexts in South America. The study provides empirically based hypotheses on therapeutic mechanisms of ayahuasca in substance dependence treatment. Findings indicate that ayahuasca can serve as a valuable therapeutic tool that, in carefully structured settings, can catalyze neurobiological and psychological processes that support recovery from substance dependencies and the prevention of relapse. Treatment outcomes, however, can be influenced by a number of variables that are explained in this study. In addition, issues related to ritual transfer and strategies for minimizing undesired side-effects are discussed.

  6. Effects of dependence in high-dimensional multiple testing problems

    Directory of Open Access Journals (Sweden)

    van de Wiel Mark A

    2008-02-01

    Full Text Available Abstract Background We consider effects of dependence among variables of high-dimensional data in multiple hypothesis testing problems, in particular the False Discovery Rate (FDR control procedures. Recent simulation studies consider only simple correlation structures among variables, which is hardly inspired by real data features. Our aim is to systematically study effects of several network features like sparsity and correlation strength by imposing dependence structures among variables using random correlation matrices. Results We study the robustness against dependence of several FDR procedures that are popular in microarray studies, such as Benjamin-Hochberg FDR, Storey's q-value, SAM and resampling based FDR procedures. False Non-discovery Rates and estimates of the number of null hypotheses are computed from those methods and compared. Our simulation study shows that methods such as SAM and the q-value do not adequately control the FDR to the level claimed under dependence conditions. On the other hand, the adaptive Benjamini-Hochberg procedure seems to be most robust while remaining conservative. Finally, the estimates of the number of true null hypotheses under various dependence conditions are variable. Conclusion We discuss a new method for efficient guided simulation of dependent data, which satisfy imposed network constraints as conditional independence structures. Our simulation set-up allows for a structural study of the effect of dependencies on multiple testing criterions and is useful for testing a potentially new method on π0 or FDR estimation in a dependency context.

  7. Response-reinforcer dependency and resistance to change.

    Science.gov (United States)

    Cançado, Carlos R X; Abreu-Rodrigues, Josele; Aló, Raquel Moreira; Hauck, Flávia; Doughty, Adam H

    2018-01-01

    The effects of the response-reinforcer dependency on resistance to change were studied in three experiments with rats. In Experiment 1, lever pressing produced reinforcers at similar rates after variable interreinforcer intervals in each component of a two-component multiple schedule. Across conditions, in the fixed component, all reinforcers were response-dependent; in the alternative component, the percentage of response-dependent reinforcers was 100, 50 (i.e., 50% response-dependent and 50% response-independent) or 10% (i.e., 10% response-dependent and 90% response-independent). Resistance to extinction was greater in the alternative than in the fixed component when the dependency in the former was 10%, but was similar between components when this dependency was 100 or 50%. In Experiment 2, a three-component multiple schedule was used. The dependency was 100% in one component and 10% in the other two. The 10% components differed on how reinforcers were programmed. In one component, as in Experiment 1, a reinforcer had to be collected before the scheduling of other response-dependent or independent reinforcers. In the other component, response-dependent and -independent reinforcers were programmed by superimposing a variable-time schedule on an independent variable-interval schedule. Regardless of the procedure used to program the dependency, resistance to extinction was greater in the 10% components than in the 100% component. These results were replicated in Experiment 3 in which, instead of extinction, VT schedules replaced the baseline schedules in each multiple-schedule component during the test. We argue that the relative change in dependency from Baseline to Test, which is greater when baseline dependencies are high rather than low, could account for the differential resistance to change in the present experiments. The inconsistencies in results across the present and previous experiments suggest that the effects of dependency on resistance to change are

  8. Potential fitting biases resulting from grouping data into variable width bins

    International Nuclear Information System (INIS)

    Towers, S.

    2014-01-01

    When reading peer-reviewed scientific literature describing any analysis of empirical data, it is natural and correct to proceed with the underlying assumption that experiments have made good faith efforts to ensure that their analyses yield unbiased results. However, particle physics experiments are expensive and time consuming to carry out, thus if an analysis has inherent bias (even if unintentional), much money and effort can be wasted trying to replicate or understand the results, particularly if the analysis is fundamental to our understanding of the universe. In this note we discuss the significant biases that can result from data binning schemes. As we will show, if data are binned such that they provide the best comparison to a particular (but incorrect) model, the resulting model parameter estimates when fitting to the binned data can be significantly biased, leading us to too often accept the model hypothesis when it is not in fact true. When using binned likelihood or least squares methods there is of course no a priori requirement that data bin sizes need to be constant, but we show that fitting to data grouped into variable width bins is particularly prone to produce biased results if the bin boundaries are chosen to optimize the comparison of the binned data to a wrong model. The degree of bias that can be achieved simply with variable binning can be surprisingly large. Fitting the data with an unbinned likelihood method, when possible to do so, is the best way for researchers to show that their analyses are not biased by binning effects. Failing that, equal bin widths should be employed as a cross-check of the fitting analysis whenever possible

  9. Potential fitting biases resulting from grouping data into variable width bins

    Energy Technology Data Exchange (ETDEWEB)

    Towers, S., E-mail: smtowers@asu.edu

    2014-07-30

    When reading peer-reviewed scientific literature describing any analysis of empirical data, it is natural and correct to proceed with the underlying assumption that experiments have made good faith efforts to ensure that their analyses yield unbiased results. However, particle physics experiments are expensive and time consuming to carry out, thus if an analysis has inherent bias (even if unintentional), much money and effort can be wasted trying to replicate or understand the results, particularly if the analysis is fundamental to our understanding of the universe. In this note we discuss the significant biases that can result from data binning schemes. As we will show, if data are binned such that they provide the best comparison to a particular (but incorrect) model, the resulting model parameter estimates when fitting to the binned data can be significantly biased, leading us to too often accept the model hypothesis when it is not in fact true. When using binned likelihood or least squares methods there is of course no a priori requirement that data bin sizes need to be constant, but we show that fitting to data grouped into variable width bins is particularly prone to produce biased results if the bin boundaries are chosen to optimize the comparison of the binned data to a wrong model. The degree of bias that can be achieved simply with variable binning can be surprisingly large. Fitting the data with an unbinned likelihood method, when possible to do so, is the best way for researchers to show that their analyses are not biased by binning effects. Failing that, equal bin widths should be employed as a cross-check of the fitting analysis whenever possible.

  10. Morphometric variability of mandible linear characteristics depending on level of teeth alveolus position

    Directory of Open Access Journals (Sweden)

    Olga Yu. Aleshkina

    2017-05-01

    Results and Conclusion ― The highest altitude was marked at levels of incisors and 3rd molar, the smallest one – at level of 1st and 2nd molars; maximum mandible thickness was defined at level of 2nd molar, minimum – at levels of canine and 1st – 2nd premolars on both sides of mandible; average thickness was revealed at levels of incisors, 1st and 2nd molars and had the same statistical values. Bilateral variability of thickness was significantly dominating on the right side and only at levels of 1st – 2nd premolars and 1st molar. Average values of altitude and thickness from both sides of mandible and at all levels had medium degree of variability.

  11. All varieties of encoding variability are not created equal: Separating variable processing from variable tasks

    Science.gov (United States)

    Huff, Mark J.; Bodner, Glen E.

    2014-01-01

    Whether encoding variability facilitates memory is shown to depend on whether item-specific and relational processing are both performed across study blocks, and whether study items are weakly versus strongly related. Variable-processing groups studied a word list once using an item-specific task and once using a relational task. Variable-task groups’ two different study tasks recruited the same type of processing each block. Repeated-task groups performed the same study task each block. Recall and recognition were greatest in the variable-processing group, but only with weakly related lists. A variable-processing benefit was also found when task-based processing and list-type processing were complementary (e.g., item-specific processing of a related list) rather than redundant (e.g., relational processing of a related list). That performing both item-specific and relational processing across trials, or within a trial, yields encoding-variability benefits may help reconcile decades of contradictory findings in this area. PMID:25018583

  12. Convergence Analysis of Semi-Implicit Euler Methods for Solving Stochastic Age-Dependent Capital System with Variable Delays and Random Jump Magnitudes

    Directory of Open Access Journals (Sweden)

    Qinghui Du

    2014-01-01

    Full Text Available We consider semi-implicit Euler methods for stochastic age-dependent capital system with variable delays and random jump magnitudes, and investigate the convergence of the numerical approximation. It is proved that the numerical approximate solutions converge to the analytical solutions in the mean-square sense under given conditions.

  13. Comparison of Maladaptive Meta Cognition Beliefs among Substance Dependents and Non-Dependents

    Directory of Open Access Journals (Sweden)

    Omid Saed

    2011-05-01

    Full Text Available Introduction: The aim of present research was the comparison of maladaptive meta cognition beliefs among substance abusers and non abusers. Methods: For this purpose 70 substance abusers and 70 individuals from the general population by purposive sampling participated in this research and responded to meta cognition questionnaire. For analysis data multiple analysis of variance (MANOVA and discriminant analysis were run. Results: MANOVA revealed that there was significant difference in linier combination of dependent variables (meta cognitive beliefs among two groups also, analysis of dependent variables lonely showed that two groups were significantly different in Positive meta cognitive beliefs, "Negative meta cognitive beliefs", "lack of cognitive confidence", "need to control of thoughts", and "cognitive self-consciousness". Also, the discriminant analysis indicated that three meta-cognitive factors included “negative meta cognitive beliefs", "need to control of thoughts" and "cognitive self-consciousness" were significant predictors to discriminate substance abusers. Conclusion: With consideration of the results it can be concluded that substance abusers have more maladaptive beliefs and these maladaptive beliefs can lead to susceptibility toward substance abuse and staying in this disorder. It is hoped that psychotherapists can be more useful in treating and staying in this research.

  14. A new method to detect transitory signatures and local time/space variability structures in the climate system: the scale-dependent correlation analysis

    Science.gov (United States)

    Rodó, Xavier; Rodríguez-Arias, Miquel-Àngel

    2006-10-01

    The study of transitory signals and local variability structures in both/either time and space and their role as sources of climatic memory, is an important but often neglected topic in climate research despite its obvious importance and extensive coverage in the literature. Transitory signals arise either from non-linearities, in the climate system, transitory atmosphere-ocean couplings, and other processes in the climate system evolving after a critical threshold is crossed. These temporary interactions that, though intense, may not last long, can be responsible for a large amount of unexplained variability but are normally considered of limited relevance and often, discarded. With most of the current techniques at hand these typology of signatures are difficult to isolate because the low signal-to-noise ratio in midlatitudes, the limited recurrence of the transitory signals during a customary interval of data considered. Also, there is often a serious problem arising from the smoothing of local or transitory processes if statistical techniques are applied, that consider all the length of data available, rather than taking into account the size of the specific variability structure under investigation. Scale-dependent correlation (SDC) analysis is a new statistical method capable of highlighting the presence of transitory processes, these former being understood as temporary significant lag-dependent autocovariance in a single series, or covariance structures between two series. This approach, therefore, complements other approaches such as those resulting from the families of wavelet analysis, singular-spectrum analysis and recurrence plots. A main feature of SDC is its high-performance for short time series, its ability to characterize phase-relationships and thresholds in the bivariate domain. Ultimately, SDC helps tracking short-lagged relationships among processes that locally or temporarily couple and uncouple. The use of SDC is illustrated in the present

  15. TEC variability over Havana

    International Nuclear Information System (INIS)

    Lazo, B.; Alazo, K.; Rodriguez, M.; Calzadilla, A.

    2003-01-01

    The variability of total electron content (TEC) measured over Havana using ATS-6, SMS-1 and GOES-3 geosynchronous satellite signals has been investigated for low, middle and high solar activity periods from 1974 to 1982. The obtained results show that standard deviation is smooth during nighttime hours and maximum at noon or postnoon hours. Strong solar activity dependence of standard deviation with a maximum values during HSA has been found. (author)

  16. A Review of Spectral Methods for Variable Amplitude Fatigue Prediction and New Results

    Science.gov (United States)

    Larsen, Curtis E.; Irvine, Tom

    2013-01-01

    A comprehensive review of the available methods for estimating fatigue damage from variable amplitude loading is presented. The dependence of fatigue damage accumulation on power spectral density (psd) is investigated for random processes relevant to real structures such as in offshore or aerospace applications. Beginning with the Rayleigh (or narrow band) approximation, attempts at improved approximations or corrections to the Rayleigh approximation are examined by comparison to rainflow analysis of time histories simulated from psd functions representative of simple theoretical and real world applications. Spectral methods investigated include corrections by Wirsching and Light, Ortiz and Chen, the Dirlik formula, and the Single-Moment method, among other more recent proposed methods. Good agreement is obtained between the spectral methods and the time-domain rainflow identification for most cases, with some limitations. Guidelines are given for using the several spectral methods to increase confidence in the damage estimate.

  17. Outer membrane targeting of Pseudomonas aeruginosa proteins shows variable dependence on the components of Bam and Lol machineries.

    Science.gov (United States)

    Hoang, Hanh H; Nickerson, Nicholas N; Lee, Vincent T; Kazimirova, Anastasia; Chami, Mohamed; Pugsley, Anthony P; Lory, Stephen

    2011-01-01

    In Gram-negative bacteria, the Lol and Bam machineries direct the targeting of lipidated and nonlipidated proteins, respectively, to the outer membrane (OM). Using Pseudomonas aeruginosa strains with depleted levels of specific Bam and Lol proteins, we demonstrated a variable dependence of different OM proteins on these targeting pathways. Reduction in the level of BamA significantly affected the ability of the β-barrel membrane protein OprF to localize to the OM, while the targeting of three secretins that are functionally related OM proteins was less affected (PilQ and PscC) or not at all affected (XcpQ). Depletion of LolB affected all lipoproteins examined and had a variable effect on the nonlipidated proteins. While the levels of OprF, PilQ, and PscC were significantly reduced by LolB depletion, XcpQ was unaffected and was correctly localized to the OM. These results suggest that certain β-barrel proteins such as OprF primarily utilize the complete Bam machinery. The Lol machinery participates in the OM targeting of secretins to variable degrees, likely through its involvement in the assembly of lipidated Bam components. XcpQ, but not PilQ or PscC, was shown to assemble spontaneously into liposomes as multimers. This work raises the possibility that there is a gradient of utilization of Bam and Lol insertion and targeting machineries. Structural features of individual proteins, including their β-barrel content, may determine the propensity of these proteins for folding (or misfolding) during periplasmic transit and OM insertion, thereby influencing the extent of utilization of the Bam targeting machinery, respectively. Targeting of lipidated and nonlipidated proteins to the outer membrane (OM) compartment in Gram-negative bacteria involves the transfer across the periplasm utilizing the Lol and Bam machineries, respectively. We show that depletion of Bam and Lol components in Pseudomonas aeruginosa does not lead to a general OM protein translocation defect

  18. A variable-order fractal derivative model for anomalous diffusion

    Directory of Open Access Journals (Sweden)

    Liu Xiaoting

    2017-01-01

    Full Text Available This paper pays attention to develop a variable-order fractal derivative model for anomalous diffusion. Previous investigations have indicated that the medium structure, fractal dimension or porosity may change with time or space during solute transport processes, results in time or spatial dependent anomalous diffusion phenomena. Hereby, this study makes an attempt to introduce a variable-order fractal derivative diffusion model, in which the index of fractal derivative depends on temporal moment or spatial position, to characterize the above mentioned anomalous diffusion (or transport processes. Compared with other models, the main advantages in description and the physical explanation of new model are explored by numerical simulation. Further discussions on the dissimilitude such as computational efficiency, diffusion behavior and heavy tail phenomena of the new model and variable-order fractional derivative model are also offered.

  19. Internally generated natural variability of global-mean temperatures

    International Nuclear Information System (INIS)

    Wigley, T.M.L.; Raper, S.C.B.

    1990-01-01

    Quantitative frequency-domain and time-domain estimates are made of an important aspect of natural variability of global-mean temperatures, namely, passive internal variability resulting from the modulation of atmospheric variability by the ocean. The results are derived using an upwelling-diffusion, energy-balance climate model. In the frequency domain, analytical spectral results show a transition from a high-frequency region in which the response is determined by the mixed-layer heat capacity and is independent of the climate sensitivity (time scales less than around 10 years), to a low-frequency region in which the response depends only on the climate sensitivity. In the former region the spectral power is proportional to f -2 , where f is the frequency, while in the latter the power is independent of frequency. The range of validity of these results depends on the components of the climate system that are included in the model. In this case these restrict the low-frequency results to time scales less than about 1,000 years. A qualitative extrapolation is presented in an attempt to explain the observed low-frequency power spectra from deep-sea-core δ 18 O time series. The spectral results are also used to estimate the effective heat capacity of the ocean as a function of frequency. At low frequencies, this can range up to 50 times greater than the heat capacity of the mixed layer. Results in the time domain are obtained by solving the model equations numerically

  20. Saddlepoint expansions for sums of Markov dependent variables on a continuous state space

    DEFF Research Database (Denmark)

    Jensen, J.L.

    1991-01-01

    Based on the conjugate kernel studied in Iscoe et al. (1985) we derive saddlepoint expansions for either the density or distribution function of a sum f(X1)+...+f(Xn), where the Xi's constitute a Markov chain. The chain is assumed to satisfy a strong recurrence condition which makes the results...... here very similar to the classical results for i.i.d. variables. In particular we establish also conditions under which the expansions hold uniformly over the range of the saddlepoint. Expansions are also derived for sums of the form f(X1, X0)+f(X2, X1)+...+f(Xn, Xn-1) although the uniformity result...

  1. Does habitat variability really promote metabolic network modularity?

    Science.gov (United States)

    Takemoto, Kazuhiro

    2013-01-01

    The hypothesis that variability in natural habitats promotes modular organization is widely accepted for cellular networks. However, results of some data analyses and theoretical studies have begun to cast doubt on the impact of habitat variability on modularity in metabolic networks. Therefore, we re-evaluated this hypothesis using statistical data analysis and current metabolic information. We were unable to conclude that an increase in modularity was the result of habitat variability. Although horizontal gene transfer was also considered because it may contribute for survival in a variety of environments, closely related to habitat variability, and is known to be positively correlated with network modularity, such a positive correlation was not concluded in the latest version of metabolic networks. Furthermore, we demonstrated that the previously observed increase in network modularity due to habitat variability and horizontal gene transfer was probably due to a lack of available data on metabolic reactions. Instead, we determined that modularity in metabolic networks is dependent on species growth conditions. These results may not entirely discount the impact of habitat variability and horizontal gene transfer. Rather, they highlight the need for a more suitable definition of habitat variability and a more careful examination of relationships of the network modularity with horizontal gene transfer, habitats, and environments.

  2. Effect of flow rate on environmental variables and phytoplankton dynamics: results from field enclosures

    Science.gov (United States)

    Zhang, Haiping; Chen, Ruihong; Li, Feipeng; Chen, Ling

    2015-03-01

    To investigate the effects of flow rate on phytoplankton dynamics and related environment variables, a set of enclosure experiments with different flow rates were conducted in an artificial lake. We monitored nutrients, temperature, dissolved oxygen, pH, conductivity, turbidity, chlorophyll- a and phytoplankton levels. The lower biomass in all flowing enclosures showed that flow rate significantly inhibited the growth of phytoplankton. A critical flow rate occurred near 0.06 m/s, which was the lowest relative inhibitory rate. Changes in flow conditions affected algal competition for light, resulting in a dramatic shift in phytoplankton composition, from blue-green algae in still waters to green algae in flowing conditions. These findings indicate that critical flow rate can be useful in developing methods to reduce algal bloom occurrence. However, flow rate significantly enhanced the inter-relationships among environmental variables, in particular by inducing higher water turbidity and vegetative reproduction of periphyton ( Spirogyra). These changes were accompanied by a decrease in underwater light intensity, which consequently inhibited the photosynthetic intensity of phytoplankton. These results warn that a universal critical flow rate might not exist, because the effect of flow rate on phytoplankton is interlinked with many other environmental variables.

  3. PaCAL: A Python Package for Arithmetic Computations with Random Variables

    Directory of Open Access Journals (Sweden)

    Marcin Korze?

    2014-05-01

    Full Text Available In this paper we present PaCAL, a Python package for arithmetical computations on random variables. The package is capable of performing the four arithmetic operations: addition, subtraction, multiplication and division, as well as computing many standard functions of random variables. Summary statistics, random number generation, plots, and histograms of the resulting distributions can easily be obtained and distribution parameter ?tting is also available. The operations are performed numerically and their results interpolated allowing for arbitrary arithmetic operations on random variables following practically any probability distribution encountered in practice. The package is easy to use, as operations on random variables are performed just as they are on standard Python variables. Independence of random variables is, by default, assumed on each step but some computations on dependent random variables are also possible. We demonstrate on several examples that the results are very accurate, often close to machine precision. Practical applications include statistics, physical measurements or estimation of error distributions in scienti?c computations.

  4. Normal forms of dispersive scalar Poisson brackets with two independent variables

    Science.gov (United States)

    Carlet, Guido; Casati, Matteo; Shadrin, Sergey

    2018-03-01

    We classify the dispersive Poisson brackets with one dependent variable and two independent variables, with leading order of hydrodynamic type, up to Miura transformations. We show that, in contrast to the case of a single independent variable for which a well-known triviality result exists, the Miura equivalence classes are parametrised by an infinite number of constants, which we call numerical invariants of the brackets. We obtain explicit formulas for the first few numerical invariants.

  5. A variable thickness window: Thermal and structural analyses

    International Nuclear Information System (INIS)

    Wang, Zhibi; Kuzay, T.M.

    1994-01-01

    In this paper, the finite difference formulations for variable thickness thermal analysis and variable thickness plane stress analysis are presented. In heat transfer analysis, radiation effects and temperature-dependent thermal conductivity are taken into account. While in thermal stress analysis, the thermal expansion coefficient is considered as temperature dependent. An application of the variable thickness window to an Advanced Photon Source beamline is presented

  6. Photometric variability in earthshine observations.

    Science.gov (United States)

    Langford, Sally V; Wyithe, J Stuart B; Turner, Edwin L

    2009-04-01

    The identification of an extrasolar planet as Earth-like will depend on the detection of atmospheric signatures or surface non-uniformities. In this paper we present spatially unresolved flux light curves of Earth for the purpose of studying a prototype extrasolar terrestrial planet. Our monitoring of the photometric variability of earthshine revealed changes of up to 23% per hour in the brightness of Earth's scattered light at around 600 nm, due to the removal of specular reflection from the view of the Moon. This variability is accompanied by reddening of the spectrum and results from a change in surface properties across the continental boundary between the Indian Ocean and Africa's east coast. Our results based on earthshine monitoring indicate that specular reflection should provide a useful tool in determining the presence of liquid water on extrasolar planets via photometric observations.

  7. Meteorological variables affect fertility rate after intrauterine artificial insemination in sheep in a seasonal-dependent manner: a 7-year study

    Science.gov (United States)

    Palacios, C.; Abecia, J. A.

    2015-05-01

    A total number of 48,088 artificial inseminations (AIs) have been controlled during seven consecutive years in 79 dairy sheep Spanish farms (41° N). Mean, maximum and minimum ambient temperatures ( Ts), temperature amplitude (TA), mean relative humidity (RH), mean solar radiation (SR) and total rainfall of each insemination day and 15 days later were recorded. Temperature-humidity index (THI) and effective temperature (ET) have been calculated. A binary logistic regression model to estimate the risk of not getting pregnant compared to getting pregnant, through the odds ratio (OR), was performed. Successful winter inseminations were carried out under higher SR ( P 1 (maximum T, ET and rainfall on AI day, and ET and rainfall on day 15), and two variables presented OR AI day and maximum T on day 15). However, the effect of meteorological factors affected fertility in opposite ways, so T becomes a protective or risk factor on fertility depending on season. In conclusion, the percentage of pregnancy after AI in sheep is significantly affected by meteorological variables in a seasonal-dependent manner, so the parameters such as temperature reverse their effects in the hot or cold seasons. A forecast of the meteorological conditions could be a useful tool when AI dates are being scheduled.

  8. Chemical Variability and Biological Activities of Brassica rapa var. rapifera Parts Essential Oils Depending on Geographic Variation and Extraction Technique.

    Science.gov (United States)

    Saka, Boualem; Djouahri, Abderrahmane; Djerrad, Zineb; Terfi, Souhila; Aberrane, Sihem; Sabaou, Nasserdine; Baaliouamer, Aoumeur; Boudarene, Lynda

    2017-06-01

    In the present work, the Brassica rapa var. rapifera parts essential oils and their antioxidant and antimicrobial activities were investigated for the first time depending on geographic origin and extraction technique. Gas-chromatography (GC) and GC/mass spectrometry (MS) analyses showed several constituents, including alcohols, aldehydes, esters, ketones, norisoprenoids, terpenic, nitrogen and sulphur compounds, totalizing 38 and 41 compounds in leaves and root essential oils, respectively. Nitrogen compounds were the main volatiles in leaves essential oils and sulphur compounds were the main volatiles in root essential oils. Qualitative and quantitative differences were found among B. rapa var. rapifera parts essential oils collected from different locations and extracted by hydrodistillation and microwave-assisted hydrodistillation techniques. Furthermore, our findings showed a high variability for both antioxidant and antimicrobial activities. The highlighted variability reflects the high impact of plant part, geographic variation and extraction technique on chemical composition and biological activities, which led to conclude that we should select essential oils to be investigated carefully depending on these factors, in order to isolate the bioactive components or to have the best quality of essential oil in terms of biological activities and preventive effects in food. © 2017 Wiley-VHCA AG, Zurich, Switzerland.

  9. Initial CGE Model Results Summary Exogenous and Endogenous Variables Tests

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, Brian Keith [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Boero, Riccardo [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Rivera, Michael Kelly [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-08-07

    The following discussion presents initial results of tests of the most recent version of the National Infrastructure Simulation and Analysis Center Dynamic Computable General Equilibrium (CGE) model developed by Los Alamos National Laboratory (LANL). The intent of this is to test and assess the model’s behavioral properties. The test evaluated whether the predicted impacts are reasonable from a qualitative perspective. This issue is whether the predicted change, be it an increase or decrease in other model variables, is consistent with prior economic intuition and expectations about the predicted change. One of the purposes of this effort is to determine whether model changes are needed in order to improve its behavior qualitatively and quantitatively.

  10. Reconstructing time-dependent dynamics

    OpenAIRE

    Clemson, Philip; Lancaster, Gemma; Stefanovska, Aneta

    2016-01-01

    The usefulness of the information extracted from biomedical data relies heavily on the underlying theory of the methods used in its extraction. The assumptions of stationarity and autonomicity traditionally applied to dynamical systems break down when considering living systems, due to their inherent time-variability. Living systems are thermodynamically open, and thus constantly interacting with their environment. This results in highly nonlinear, time-dependent dynamics. The aim of signal a...

  11. Variable features on Mars - Preliminary Mariner 9 television results.

    Science.gov (United States)

    Sagan, C.; Veverka, J.; Fox, P.; Dubisch, R.; Lederberg, J.; Levinthal, E.; Quam, L.; Tucker, R.; Pollack, J. B.; Smith, B. A.

    1972-01-01

    Systematic Mariner 9 photography of a range of Martian surface features, observed with all three photometric angles approximately invariant, reveals three general categories of albedo variations: (1) an essentially uniform contrast enhancement due to the dissipation of the dust storm; (2) the appearance of splotches, irregular dark markings at least partially related to topography; and (3) the development of both bright and dark linear streaks, generally emanating from craters. Some splotches and streaks vary on characteristic timescales of about two weeks; they have characteristic dimensions of kilometers to tens of kilometers. The morphology and variability of streaks and splotches, and the resolution of at least one splotch into an extensive dune system, implicate windblown dust as the principal agent of Martian albedo differences and variability.

  12. A Core Language for Separate Variability Modeling

    DEFF Research Database (Denmark)

    Iosif-Lazăr, Alexandru Florin; Wasowski, Andrzej; Schaefer, Ina

    2014-01-01

    Separate variability modeling adds variability to a modeling language without requiring modifications of the language or the supporting tools. We define a core language for separate variability modeling using a single kind of variation point to define transformations of software artifacts in object...... hierarchical dependencies between variation points via copying and flattening. Thus, we reduce a model with intricate dependencies to a flat executable model transformation consisting of simple unconditional local variation points. The core semantics is extremely concise: it boils down to two operational rules...

  13. On Direction of Dependence in Latent Variable Contexts

    Science.gov (United States)

    von Eye, Alexander; Wiedermann, Wolfgang

    2014-01-01

    Approaches to determining direction of dependence in nonexperimental data are based on the relation between higher-than second-order moments on one side and correlation and regression models on the other. These approaches have experienced rapid development and are being applied in contexts such as research on partner violence, attention deficit…

  14. The association between e-cigarette use characteristics and combustible cigarette consumption and dependence symptoms: Results from a national longitudinal study.

    Science.gov (United States)

    Buu, Anne; Hu, Yi-Han; Piper, Megan E; Lin, Hsien-Chang

    2018-09-01

    Existing longitudinal surveys focused on the association between ever use of e-cigarettes and combustible cigarette consumption, making it difficult to infer what characteristics of e-cigarette use could potentially change combustible cigarette use behavior, which may have long-term health consequences. Although e-cigarettes' efficacy of alleviating dependence symptoms was supported by studies conducted in laboratory settings, whether the results can be translated into symptom reduction in the real world and over time is an open question. This study conducted secondary analysis on the Waves 1-2 data of the Population Assessment of Tobacco and Health (PATH) Study to examine the association between e-cigarette use characteristics (frequency, flavoring, and voltage adjustment) and combustible cigarette use outcomes (frequency, quantity, and symptoms), using the Heckman 2-step selection procedure with the selection bias controlled. The inclusion criteria ensured that we followed an adult cohort of exclusive combustible cigarette users at Wave 1. The result shows that higher frequency of e-cigarette use was associated with lower combustible cigarette consumption and dependence symptoms, controlling for the corresponding baseline cigarette use variable and other confounders. Given the frequency of e-cigarette use, the feature of voltage adjustment was not significantly associated with any of the cigarette use outcomes. Flavoring, on the other hand, was associated with lower quantity of cigarette use. Exclusive smokers who start using e-cigarettes do indeed change the frequency and quantity with which they smoke cigarettes. E-cigarette use may also help reduce dependence symptoms. Copyright © 2018 Elsevier Ltd. All rights reserved.

  15. Human reliability analysis of dependent events

    International Nuclear Information System (INIS)

    Swain, A.D.; Guttmann, H.E.

    1977-01-01

    In the human reliability analysis in WASH-1400, the continuous variable of degree of interaction among human events was approximated by selecting four points on this continuum to represent the entire continuum. The four points selected were identified as zero coupling (i.e., zero dependence), complete coupling (i.e., complete dependence), and two intermediate points--loose coupling (a moderate level of dependence) and tight coupling (a high level of dependence). The paper expands the WASH-1400 treatment of common mode failure due to the interaction of human activities. Mathematical expressions for the above four levels of dependence are derived for parallel and series systems. The psychological meaning of each level of dependence is illustrated by examples, with probability tree diagrams to illustrate the use of conditional probabilities resulting from the interaction of human actions in nuclear power plant tasks

  16. Existence results for impulsive neutral functional differential equations with state-dependent delay

    Directory of Open Access Journals (Sweden)

    Mani Mallika Arjunan

    2009-04-01

    Full Text Available In this article, we study the existence of mild solutions for a class of impulsive abstract partial neutral functional differential equations with state-dependent delay. The results are obtained by using Leray-Schauder Alternative fixed point theorem. Example is provided to illustrate the main result.

  17. The dynamics of variable-density turbulence

    International Nuclear Information System (INIS)

    Sandoval, D.L.

    1995-11-01

    The dynamics of variable-density turbulent fluids are studied by direct numerical simulation. The flow is incompressible so that acoustic waves are decoupled from the problem, and implying that density is not a thermodynamic variable. Changes in density occur due to molecular mixing. The velocity field, is in general, divergent. A pseudo-spectral numerical technique is used to solve the equations of motion. Three-dimensional simulations are performed using a grid size of 128 3 grid points. Two types of problems are studied: (1) the decay of isotropic, variable-density turbulence, and (2) buoyancy-generated turbulence in a fluid with large density fluctuations. In the case of isotropic, variable-density turbulence, the overall statistical decay behavior, for the cases studied, is relatively unaffected by the presence of density variations when the initial density and velocity fields are statistically independent. The results for this case are in quantitative agreement with previous numerical and laboratory results. In this case, the initial density field has a bimodal probability density function (pdf) which evolves in time towards a Gaussian distribution. The pdf of the density field is symmetric about its mean value throughout its evolution. If the initial velocity and density fields are statistically dependent, however, the decay process is significantly affected by the density fluctuations. For the case of buoyancy-generated turbulence, variable-density departures from the Boussinesq approximation are studied. The results of the buoyancy-generated turbulence are compared with variable-density model predictions. Both a one-point (engineering) model and a two-point (spectral) model are tested against the numerical data. Some deficiencies in these variable-density models are discussed and modifications are suggested

  18. Estimation of AUC or Partial AUC under Test-Result-Dependent Sampling.

    Science.gov (United States)

    Wang, Xiaofei; Ma, Junling; George, Stephen; Zhou, Haibo

    2012-01-01

    The area under the ROC curve (AUC) and partial area under the ROC curve (pAUC) are summary measures used to assess the accuracy of a biomarker in discriminating true disease status. The standard sampling approach used in biomarker validation studies is often inefficient and costly, especially when ascertaining the true disease status is costly and invasive. To improve efficiency and reduce the cost of biomarker validation studies, we consider a test-result-dependent sampling (TDS) scheme, in which subject selection for determining the disease state is dependent on the result of a biomarker assay. We first estimate the test-result distribution using data arising from the TDS design. With the estimated empirical test-result distribution, we propose consistent nonparametric estimators for AUC and pAUC and establish the asymptotic properties of the proposed estimators. Simulation studies show that the proposed estimators have good finite sample properties and that the TDS design yields more efficient AUC and pAUC estimates than a simple random sampling (SRS) design. A data example based on an ongoing cancer clinical trial is provided to illustrate the TDS design and the proposed estimators. This work can find broad applications in design and analysis of biomarker validation studies.

  19. Predictive model of nicotine dependence based on mental health indicators and self-concept

    Directory of Open Access Journals (Sweden)

    Hamid Kazemi Zahrani

    2014-12-01

    Full Text Available Background: The purpose of this research was to investigate the predictive power of anxiety, depression, stress and self-concept dimensions (Mental ability, job efficiency, physical attractiveness, social skills, and deficiencies and merits as predictors of nicotine dependency among university students in Isfahan. Methods: In this correlational study, 110 male nicotine-dependent students at Isfahan University were selected by convenience sampling. All samples were assessed by Depression Anxiety Stress Scale (DASS, self-concept test and Nicotine Dependence Syndrome Scale. Data were analyzed by Pearson correlation and stepwise regression. Results: The result showed that anxiety had the highest strength to predict nicotine dependence. In addition, the self-concept and its dimensions predicted only 12% of the variance in nicotine dependence, which was not significant. Conclusion: Emotional processing variables involved in mental health play an important role in presenting a model to predict students’ dependence on nicotine more than identity variables such as different dimensions of self-concept.

  20. Performance prediction for silicon photonics integrated circuits with layout-dependent correlated manufacturing variability.

    Science.gov (United States)

    Lu, Zeqin; Jhoja, Jaspreet; Klein, Jackson; Wang, Xu; Liu, Amy; Flueckiger, Jonas; Pond, James; Chrostowski, Lukas

    2017-05-01

    This work develops an enhanced Monte Carlo (MC) simulation methodology to predict the impacts of layout-dependent correlated manufacturing variations on the performance of photonics integrated circuits (PICs). First, to enable such performance prediction, we demonstrate a simple method with sub-nanometer accuracy to characterize photonics manufacturing variations, where the width and height for a fabricated waveguide can be extracted from the spectral response of a racetrack resonator. By measuring the spectral responses for a large number of identical resonators spread over a wafer, statistical results for the variations of waveguide width and height can be obtained. Second, we develop models for the layout-dependent enhanced MC simulation. Our models use netlist extraction to transfer physical layouts into circuit simulators. Spatially correlated physical variations across the PICs are simulated on a discrete grid and are mapped to each circuit component, so that the performance for each component can be updated according to its obtained variations, and therefore, circuit simulations take the correlated variations between components into account. The simulation flow and theoretical models for our layout-dependent enhanced MC simulation are detailed in this paper. As examples, several ring-resonator filter circuits are studied using the developed enhanced MC simulation, and statistical results from the simulations can predict both common-mode and differential-mode variations of the circuit performance.

  1. The Variability of Atmospheric Deuterium Brightness at Mars: Evidence for Seasonal Dependence

    Science.gov (United States)

    Mayyasi, Majd; Clarke, John; Bhattacharyya, Dolon; Deighan, Justin; Jain, Sonal; Chaffin, Michael; Thiemann, Edward; Schneider, Nick; Jakosky, Bruce

    2017-10-01

    The enhanced ratio of deuterium to hydrogen on Mars has been widely interpreted as indicating the loss of a large column of water into space, and the hydrogen content of the upper atmosphere is now known to be highly variable. The variation in the properties of both deuterium and hydrogen in the upper atmosphere of Mars is indicative of the dynamical processes that produce these species and propagate them to altitudes where they can escape the planet. Understanding the seasonal variability of D is key to understanding the variability of the escape rate of water from Mars. Data from a 15 month observing campaign, made by the Mars Atmosphere and Volatile Evolution Imaging Ultraviolet Spectrograph high-resolution echelle channel, are used to determine the brightness of deuterium as observed at the limb of Mars. The D emission is highly variable, with a peak in brightness just after southern summer solstice. The trends of D brightness are examined against extrinsic as well as intrinsic sources. It is found that the fluctuations in deuterium brightness in the upper atmosphere of Mars (up to 400 km), corrected for periodic solar variations, vary on timescales that are similar to those of water vapor fluctuations lower in the atmosphere (20-80 km). The observed variability in deuterium may be attributed to seasonal factors such as regional dust storm activity and subsequent circulation lower in the atmosphere.

  2. Relationship between dependence on modern communication tools and psychological well-being in students

    Directory of Open Access Journals (Sweden)

    Narges Afradi

    2017-06-01

    Full Text Available Nowadays due to technological advance and its direct impact on the quality of human life, addressing the issue of health and its determinants is very important. Maintaining public health is one of the most fundamental issues in each community. The aim of the study was to survey relationship between dependence on modern communication tools (internet and mobile phones and psychological well-being. 300 university students was selected according to cluster sampling method. The questionnaires were distributed to the students and 141 completed questionnaires were collected. The Young Internet addiction test and mobile phone addiction index were used to measure the predictor variables and the Ryff psychological well-being scale was used for the criterion variable. Multiple regression analysis gave a multiple correlation coefficient (R of 0.347 and adjusted coefficient of determination (R2 of 0.120. According to the calculated Beta values, the variable of dependence on mobile phones with the value of 0.196 showed the greatest power for explaining the autonomy component. The results showed a significant negative relationship between independent variables, i.e. dependence on the Internet and mobile phones, and dependent variables, i.e. psychological well-being and its components.

  3. Quantitative variability of renewable energy resources in Norway

    Science.gov (United States)

    Christakos, Konstantinos; Varlas, George; Cheliotis, Ioannis; Aalstad, Kristoffer; Papadopoulos, Anastasios; Katsafados, Petros; Steeneveld, Gert-Jan

    2017-04-01

    Based on European Union (EU) targets for 2030, the share of renewable energy (RE) consumption should be increased at 27%. RE resources such as hydropower, wind, wave power and solar power are strongly depending on the chaotic behavior of the weather conditions and climate. Due to this dependency, the prediction of the spatiotemporal variability of the RE resources is more crucial factor than in other energy resources (i.e. carbon based energy). The fluctuation of the RE resources can affect the development of the RE technologies, the energy grid, supply and prices. This study investigates the variability of the potential RE resources in Norway. More specifically, hydropower, wind, wave, and solar power are quantitatively analyzed and correlated with respect to various spatial and temporal scales. In order to analyze the diversities and their interrelationships, reanalysis and observational data of wind, precipitation, wave, and solar radiation are used for a quantitative assessment. The results indicate a high variability of marine RE resources in the North Sea and the Norwegian Sea.

  4. Global variables and the dynamics or relativistic nucleus-nucleus collisions

    International Nuclear Information System (INIS)

    Cugnon, J.; L'Hote, D.

    1983-01-01

    Various global variables providing a simple description of high multiplicity events are reviewed. Many of them are calculated in the framework of an intra-nuclear cascade model, which describes the collision process as a series of binary on-shell relativistic baryon-baryon collisions and which includes inelasticity through the production of δ-resonances. The calculations are first made for the Ar+KCl system at 0.8 GeV/A, with global variables including either all the nucleons or only the participant nucleons. The shape and the orientation of the ellipsoid of sphericity are particularly investigated. For both cases, on the average, the large axis of the ellipsoid is found to point in the beam direction. This result is discussed in comparison with hydrodynamics predictions and in relation with the mean free path. A kind of small 'bounce-off effect' is detected for intermediate impact parameters. The possibility of extracting the value of the impact parameter b from the value of a global variable is shown to depend upon the variation of this variable with b and upon the fluctuation of the global variable for a given impact parameter. A quality factor is defined to quantify this possibility. No current global variable seems to be more appropriate than the number of participant nucleons for the impact parameter selection. The physical origin of the fluctuations inside the intranuclear cascade model is discussed and the possibility of extracting useful information on the dynamics of the system from the fluctuations is pointed out. The energy dependence of our results is discussed. Some results of the calculations at 250 and 400 MeV/A are also presented for the same system Ar+KCl. (orig.)

  5. A Non-Gaussian Spatial Generalized Linear Latent Variable Model

    KAUST Repository

    Irincheeva, Irina; Cantoni, Eva; Genton, Marc G.

    2012-01-01

    We consider a spatial generalized linear latent variable model with and without normality distributional assumption on the latent variables. When the latent variables are assumed to be multivariate normal, we apply a Laplace approximation. To relax the assumption of marginal normality in favor of a mixture of normals, we construct a multivariate density with Gaussian spatial dependence and given multivariate margins. We use the pairwise likelihood to estimate the corresponding spatial generalized linear latent variable model. The properties of the resulting estimators are explored by simulations. In the analysis of an air pollution data set the proposed methodology uncovers weather conditions to be a more important source of variability than air pollution in explaining all the causes of non-accidental mortality excluding accidents. © 2012 International Biometric Society.

  6. A Non-Gaussian Spatial Generalized Linear Latent Variable Model

    KAUST Repository

    Irincheeva, Irina

    2012-08-03

    We consider a spatial generalized linear latent variable model with and without normality distributional assumption on the latent variables. When the latent variables are assumed to be multivariate normal, we apply a Laplace approximation. To relax the assumption of marginal normality in favor of a mixture of normals, we construct a multivariate density with Gaussian spatial dependence and given multivariate margins. We use the pairwise likelihood to estimate the corresponding spatial generalized linear latent variable model. The properties of the resulting estimators are explored by simulations. In the analysis of an air pollution data set the proposed methodology uncovers weather conditions to be a more important source of variability than air pollution in explaining all the causes of non-accidental mortality excluding accidents. © 2012 International Biometric Society.

  7. Frequency dependent changes in NMDAR-dependent synaptic plasticity

    Directory of Open Access Journals (Sweden)

    Arvind eKumar

    2011-09-01

    Full Text Available The NMDAR-dependent synaptic plasticity is thought to mediate several forms of learning, and can be induced by spike trains containing a small number of spikes occurring with varying rates and timing, as well as with oscillations. We computed the influence of these variables on the plasticity induced at a single NMDAR containing synapse using a reduced model that was analytically tractable, and these findings were confirmed using detailed, multi-compartment model. In addition to explaining diverse experimental results about the rate and timing dependence of synaptic plasticity, the model made several novel and testable predictions. We found that there was a preferred frequency for inducing long-term potentiation (LTP such that higher frequency stimuli induced lesser LTP, decreasing as 1/f when the number of spikes in the stimulus was kept fixed. Among other things, the preferred frequency for inducing LTP varied as a function of the distance of the synapse from the soma. In fact, same stimulation frequencies could induce LTP or LTD depending on the dendritic location of the synapse. Next, we found that rhythmic stimuli induced greater plasticity then irregular stimuli. Furthermore, brief bursts of spikes significantly expanded the timing dependence of plasticity. Finally, we found that in the ~5-15Hz frequency range both rate- and timing-dependent plasticity mechanisms work synergistically to render the synaptic plasticity most sensitive to spike-timing. These findings provide computational evidence that oscillations can have a profound influence on the plasticity of an NMDAR-dependent synapse, and show a novel role for the dendritic morphology in this process.

  8. Revealing the ultrafast outflow in IRAS 13224-3809 through spectral variability

    Science.gov (United States)

    Parker, M. L.; Alston, W. N.; Buisson, D. J. K.; Fabian, A. C.; Jiang, J.; Kara, E.; Lohfink, A.; Pinto, C.; Reynolds, C. S.

    2017-08-01

    We present an analysis of the long-term X-ray variability of the extreme narrow-line Seyfert 1 galaxy IRAS 13224-3809 using principal component analysis (PCA) and fractional excess variability (Fvar) spectra to identify model-independent spectral components. We identify a series of variability peaks in both the first PCA component and Fvar spectrum which correspond to the strongest predicted absorption lines from the ultrafast outflow (UFO) discovered by Parker et al. (2017). We also find higher order PCA components, which correspond to variability of the soft excess and reflection features. The subtle differences between RMS and PCA results argue that the observed flux-dependence of the absorption is due to increased ionization of the gas, rather than changes in column density or covering fraction. This result demonstrates that we can detect outflows from variability alone and that variability studies of UFOs are an extremely promising avenue for future research.

  9. Migrants Remittances Influence on Fiscal Sustainability in Dependent Economies

    Directory of Open Access Journals (Sweden)

    Liliana Simionescu

    2017-08-01

    Full Text Available Migrants’ remittances are an important financial flow to their country of origin. Remittances sent by migrants reduce the level and severity of poverty in developing countries. Householders use this money received from migrants for their private consumption and their investments. This paper aims to analyse the impact of remittances on economic growth, private consumption, private investments and the government tax revenue in low and upper middle-income countries. The paper highlights one of the important migration’s drivers, respectively economic reasons. Our findings are based on data from 74 developing countries collected for the period between 1989 and 2015. Using a panel data set , our results show that migrants’ remittances are positively related with economic growth and private consumption expenditure. Moreover, the results also indicate that variables such as age dependency ratio and the number of individuals holding an account at a financial institution are statistically significant in models having GDP per capita and private consumption as dependent variables. Furthermore, our results show that migrants’ remittances are associated with government tax revenue and real interest rate when instrumental variables were used.

  10. Illicit drug use and abuse/dependence: modeling of two-stage variables using the CCC approach.

    Science.gov (United States)

    Agrawal, A; Neale, M C; Jacobson, K C; Prescott, C A; Kendler, K S

    2005-06-01

    Drug use and abuse/dependence are stages of a complex drug habit. Most genetically informative models that are fit to twin data examine drug use and abuse/dependence independent of each other. This poses an interesting question: for a multistage process, how can we partition the factors influencing each stage specifically from the factors that are common to both stages? We used a causal-common-contingent (CCC) model to partition the common and specific influences on drug use and abuse/dependence. Data on use and abuse/dependence of cannabis, cocaine, sedatives, stimulants and any illicit drug was obtained from male and female twin pairs. CCC models were tested individually for each sex and in a sex-equal model. Our results suggest that there is evidence for additive genetic, shared environmental and unique environmental influences that are common to illicit drug use and abuse/dependence. Furthermore, we found substantial evidence for factors that were specific to abuse/dependence. Finally, sexes could be equated for all illicit drugs. The findings of this study emphasize the need for models that can partition the sources of individual differences into common and stage-specific influences.

  11. Using ERA-Interim reanalysis for creating datasets of energy-relevant climate variables

    Science.gov (United States)

    Jones, Philip D.; Harpham, Colin; Troccoli, Alberto; Gschwind, Benoit; Ranchin, Thierry; Wald, Lucien; Goodess, Clare M.; Dorling, Stephen

    2017-07-01

    The construction of a bias-adjusted dataset of climate variables at the near surface using ERA-Interim reanalysis is presented. A number of different, variable-dependent, bias-adjustment approaches have been proposed. Here we modify the parameters of different distributions (depending on the variable), adjusting ERA-Interim based on gridded station or direct station observations. The variables are air temperature, dewpoint temperature, precipitation (daily only), solar radiation, wind speed, and relative humidity. These are available on either 3 or 6 h timescales over the period 1979-2016. The resulting bias-adjusted dataset is available through the Climate Data Store (CDS) of the Copernicus Climate Change Data Store (C3S) and can be accessed at present from climate.copernicus.eu" target="_blank">ftp://ecem.climate.copernicus.eu. The benefit of performing bias adjustment is demonstrated by comparing initial and bias-adjusted ERA-Interim data against gridded observational fields.

  12. A mechanistic analysis of density dependence in algal population dynamics

    Directory of Open Access Journals (Sweden)

    Adrian eBorlestean

    2015-04-01

    Full Text Available Population density regulation is a fundamental principle in ecology, but the specific process underlying functional expression of density dependence remains to be fully elucidated. One view contends that patterns of density dependence are largely fixed across a species irrespective of environmental conditions, whereas another is that the strength and expression of density dependence are fundamentally variable depending on the nature of exogenous or endogenous constraints acting on the population. We conducted a study investigating the expression of density dependence in Chlamydomonas spp. grown under a gradient from low to high nutrient density. We predicted that the relationship between per capita growth rate (pgr and population density would vary from concave up to concave down as nutrient density became less limiting and populations experienced weaker density regulation. Contrary to prediction, we found that the relationship between pgr and density became increasingly concave-up as nutrient levels increased. We also found that variation in pgr increased, and pgr levels reached higher maxima in nutrient-limited environments. Most likely, these results are attributable to population growth suppression in environments with high intraspecific competition due to limited nutrient resources. Our results suggest that density regulation is strongly variable depending on exogenous and endogenous processes acting on the population, implying that expression of density dependence depends extensively on local conditions. Additional experimental work should reveal the mechanisms influencing how the expression of density dependence varies across populations through space and time.

  13. A survey for variable young stars with small telescopes: First results from HOYS-CAPS

    Science.gov (United States)

    Froebrich, D.; Campbell-White, J.; Scholz, A.; Eislöffel, J.; Zegmott, T.; Billington, S. J.; Donohoe, J.; Makin, S. V.; Hibbert, R.; Newport, R. J.; Pickard, R.; Quinn, N.; Rodda, T.; Piehler, G.; Shelley, M.; Parkinson, S.; Wiersema, K.; Walton, I.

    2018-05-01

    Variability in Young Stellar Objects (YSOs) is one of their primary characteristics. Long-term, multi-filter, high-cadence monitoring of large YSO samples is the key to understand the partly unusual light-curves that many of these objects show. Here we introduce and present the first results of the HOYS-CAPScitizen science project which aims to perform such monitoring for nearby (d < 1 kpc) and young (age < 10 Myr) clusters and star forming regions, visible from the northern hemisphere, with small telescopes. We have identified and characterised 466 variable (413 confirmed young) stars in 8 young, nearby clusters. All sources vary by at least 0.2 mag in V, have been observed at least 15 times in V, R and I in the same night over a period of about 2 yrs and have a Stetson index of larger than 1. This is one of the largest samples of variable YSOs observed over such a time-span and cadence in multiple filters. About two thirds of our sample are classical T-Tauri stars, while the rest are objects with depleted or transition disks. Objects characterised as bursters show by far the highest variability. Dippers and objects whose variability is dominated by occultations from normal interstellar dust or dust with larger grains (or opaque material) have smaller amplitudes. We have established a hierarchical clustering algorithm based on the light-curve properties which allows the identification of the YSOs with the most unusual behaviour, and to group sources with similar properties. We discuss in detail the light-curves of the unusual objects V2492 Cyg, V350 Cep and 2MASS J21383981+5708470.

  14. Evaluating the Impact of Antibiotic Exposures as Time-Dependent Variables on the Acquisition of Carbapenem-Resistant Acinetobacter baumannii.

    Science.gov (United States)

    Munoz-Price, L Silvia; Rosa, Rossana; Castro, Jose G; Laowansiri, Panthipa; Latibeaudiere, Rachel; Namias, Nicholas; Tarima, Sergey

    2016-10-01

    To determine the time-dependent effect of antibiotics on the initial acquisition of carbapenem-resistant Acinetobacter baumannii. Retrospective cohort study. Forty-bed trauma ICU in Miami, FL. All consecutive patients admitted to the unit from November 1, 2010, to November 30, 2011. None. Patients underwent surveillance cultures at admission to the unit and weekly thereafter. The primary outcome was the acquisition of carbapenem-resistant A. baumannii on surveillance cultures. Daily antibiotic exposures during the time of observation were used to construct time-dependent variables, including cumulative exposures (in grams and daily observed doses [defined daily doses]). Among 360 patients, 45 (12.5%) became colonized with carbapenem-resistant A. baumannii. Adjusted Cox models showed that each additional point in the Acute Physiologic and Chronic Health Evaluation score increased the hazard by 4.8% (hazard ratio, 1.048; 95% CI, 1.010-1.087; p = 0.0124) and time-dependent exposure to carbapenems quadrupled the hazard (hazard ratio, 4.087; 95% CI, 1.873-8.920; p = 0.0004) of acquiring carbapenem-resistant A. baumannii. Additionally, adjusted Cox models determined that every additional carbapenem defined daily dose increased the hazard of acquiring carbapenem-resistant A. baumannii by 5.1% (hazard ratio, 1.051; 95% CI, 1.007-1.093; p = 0.0243). Carbapenem exposure quadrupled the hazards of acquiring A. baumannii even after controlling for severity of illness.

  15. Regional impacts of ocean color on tropical Pacific variability

    Science.gov (United States)

    Anderson, W.; Gnanadesikan, A.; Wittenberg, A.

    2009-08-01

    The role of the penetration length scale of shortwave radiation into the surface ocean and its impact on tropical Pacific variability is investigated with a fully coupled ocean, atmosphere, land and ice model. Previous work has shown that removal of all ocean color results in a system that tends strongly towards an El Niño state. Results from a suite of surface chlorophyll perturbation experiments show that the mean state and variability of the tropical Pacific is highly sensitive to the concentration and distribution of ocean chlorophyll. Setting the near-oligotrophic regions to contain optically pure water warms the mean state and suppresses variability in the western tropical Pacific. Doing the same above the shadow zones of the tropical Pacific also warms the mean state but enhances the variability. It is shown that increasing penetration can both deepen the pycnocline (which tends to damp El Niño) while shifting the mean circulation so that the wind response to temperature changes is altered. Depending on what region is involved this change in the wind stress can either strengthen or weaken ENSO variability.

  16. Influence of Flow Sequencing Attributed to Climate Change and Climate Variability on the Assessment of Water-dependent Ecosystem Outcomes

    Science.gov (United States)

    Wang, J.; Nathan, R.; Horne, A.

    2017-12-01

    Traditional approaches to characterize water-dependent ecosystem outcomes in response to flow have been based on time-averaged hydrological indicators, however there is increasing recognition for the need to characterize ecological processes that are highly dependent on the sequencing of flow conditions (i.e. floods and droughts). This study considers the representation of flow regimes when considering assessment of ecological outcomes, and in particular, the need to account for sequencing and variability of flow. We conducted two case studies - one in the largely unregulated Ovens River catchment and one in the highly regulated Murray River catchment (both located in south-eastern Australia) - to explore the importance of flow sequencing to the condition of a typical long-lived ecological asset in Australia, the River Red Gum forests. In the first, the Ovens River case study, the implications of representing climate change using different downscaling methods (annual scaling, monthly scaling, quantile mapping, and weather generator method) on the sequencing of flows and resulting ecological outcomes were considered. In the second, the Murray River catchment, sequencing within a historic drought period was considered by systematically making modest adjustments on an annual basis to the hydrological records. In both cases, the condition of River Red Gum forests was assessed using an ecological model that incorporates transitions between ecological conditions in response to sequences of required flow components. The results of both studies show the importance of considering how hydrological alterations are represented when assessing ecological outcomes. The Ovens case study showed that there is significant variation in the predicted ecological outcomes when different downscaling techniques are applied. Similarly, the analysis in the Murray case study showed that the drought as it historically occurred provided one of the best possible outcomes for River Red Gum

  17. Variable gearing in a biologically inspired pneumatic actuator array

    International Nuclear Information System (INIS)

    Azizi, Emanuel; Roberts, Thomas J

    2013-01-01

    A fundamental feature of pennate muscles is that muscle fibers are oriented at an angle to the line of action and rotate as they shorten, becoming more oblique throughout a contraction. This change in fiber orientation (pennation angle) can amplify the shortening velocity of a fiber and increase output velocity of the muscle. The velocity advantage resulting from dynamic changes in pennation angle can be characterized as a gear ratio (muscle velocity/fiber velocity). A recent study has shown that a pennate muscle's gear ratio varies automatically depending on the load such that a muscle operates with a high gear during rapid contractions and low gear during forceful contractions. We examined whether this variable gearing behavior can be replicated in a pennate array of artificial muscles. We used McKibben type pneumatic actuators, which shorten in tension when filled with compressed gas. Similar to muscle fibers, the actuators expand radially during shortening, a feature thought to be a critical part of the variable gearing mechanism in pennate muscles. We arranged McKibben actuators in an array oriented to mimic a pennate muscle, and quantified the system's gear ratio during contraction against a range of loads. Video was used to measure the gear ratio during each contraction. We find that similar to pennate muscles, the gear ratio decreases significantly with increasing load and that variable gearing results from load-dependent variation in the amount of actuator rotation. These results support the idea that variable gearing in pennate muscles is mediated by difference is fiber rotation and the direction of muscle bulging. The behavior of our artificial muscle array also highlights the potential benefits of bio-inspired architectures in artificial muscle arrays, including the ability to vary force and speed automatically in response to variable loading conditions. (paper)

  18. Variable gearing in a biologically inspired pneumatic actuator array.

    Science.gov (United States)

    Azizi, Emanuel; Roberts, Thomas J

    2013-06-01

    A fundamental feature of pennate muscles is that muscle fibers are oriented at an angle to the line of action and rotate as they shorten, becoming more oblique throughout a contraction. This change in fiber orientation (pennation angle) can amplify the shortening velocity of a fiber and increase output velocity of the muscle. The velocity advantage resulting from dynamic changes in pennation angle can be characterized as a gear ratio (muscle velocity/fiber velocity). A recent study has shown that a pennate muscle's gear ratio varies automatically depending on the load such that a muscle operates with a high gear during rapid contractions and low gear during forceful contractions. We examined whether this variable gearing behavior can be replicated in a pennate array of artificial muscles. We used McKibben type pneumatic actuators, which shorten in tension when filled with compressed gas. Similar to muscle fibers, the actuators expand radially during shortening, a feature thought to be a critical part of the variable gearing mechanism in pennate muscles. We arranged McKibben actuators in an array oriented to mimic a pennate muscle, and quantified the system's gear ratio during contraction against a range of loads. Video was used to measure the gear ratio during each contraction. We find that similar to pennate muscles, the gear ratio decreases significantly with increasing load and that variable gearing results from load-dependent variation in the amount of actuator rotation. These results support the idea that variable gearing in pennate muscles is mediated by difference is fiber rotation and the direction of muscle bulging. The behavior of our artificial muscle array also highlights the potential benefits of bio-inspired architectures in artificial muscle arrays, including the ability to vary force and speed automatically in response to variable loading conditions.

  19. VARIABLE GEARING IN A BIOLOGICALLY-INSPIRED PNEUMATIC ACTUATOR ARRAY

    Science.gov (United States)

    Azizi, Emanuel; Roberts, Thomas J.

    2013-01-01

    A fundamental feature of pennate muscles is that muscle fibers are oriented at an angle to the line of action and rotate as they shorten, becoming more oblique throughout a contraction. This change in fiber orientation (pennation angle) can amplify the shortening velocity of a fiber and increase output velocity of the muscle. The velocity advantage resulting from dynamic changes in pennation angle can be characterized as a gear ratio (muscle velocity/fiber velocity). A recent study has shown that a pennate muscle’s gear ratio varies automatically depending on the load such that a muscle operates with a high gear during rapid contractions and low gear during forceful contractions. We examined whether this variable gearing behavior can be replicated in a pennate array of artificial muscles. We used McKibben type pneumatic actuators, which shorten in tension when filled with compressed gas. Similar to muscle fibers, the actuators expand radially during shortening, a feature thought to be a critical part of the variable gearing mechanism in pennate muscles. We arranged McKibben actuators in an array oriented to mimic a pennate muscle, and quantified the system’s gear ratio during contraction against a range of loads. Video was used to measure the gear ratio during each contraction. We find that similar to pennate muscles, the gear ratio decreases significantly with increasing load and that variable gearing results from load-dependent variation in the amount of actuator rotation. These results support the idea that variable gearing in pennate muscles is mediated by difference is fiber rotation and the direction of muscle bulging. The behavior of our artificial muscle array also highlights the potential benefits of bio-inspired architectures in artificial muscle arrays, including the ability to vary force and speed automatically in response to variable loading conditions. PMID:23462288

  20. Contribution of execution noise to arm movement variability in three-dimensional space.

    Science.gov (United States)

    Apker, Gregory A; Buneo, Christopher A

    2012-01-01

    Reaching movements are subject to noise associated with planning and execution, but precisely how these noise sources interact to determine patterns of endpoint variability in three-dimensional space is not well understood. For frontal plane movements, variability is largest along the depth axis (the axis along which visual planning noise is greatest), with execution noise contributing to this variability along the movement direction. Here we tested whether these noise sources interact in a similar way for movements directed in depth. Subjects performed sequences of two movements from a single starting position to targets that were either both contained within a frontal plane ("frontal sequences") or where the first was within the frontal plane and the second was directed in depth ("depth sequences"). For both sequence types, movements were performed with or without visual feedback of the hand. When visual feedback was available, endpoint distributions for frontal and depth sequences were generally anisotropic, with the principal axes of variability being strongly aligned with the depth axis. Without visual feedback, endpoint distributions for frontal sequences were relatively isotropic and movement direction dependent, while those for depth sequences were similar to those with visual feedback. Overall, the results suggest that in the presence of visual feedback, endpoint variability is dominated by uncertainty associated with planning and updating visually guided movements. In addition, the results suggest that without visual feedback, increased uncertainty in hand position estimation effectively unmasks the effect of execution-related noise, resulting in patterns of endpoint variability that are highly movement direction dependent.

  1. Variability in the Precision of Children’s Spatial Working Memory

    Directory of Open Access Journals (Sweden)

    Elena M. Galeano Weber

    2018-02-01

    Full Text Available Cognitive modeling studies in adults have established that visual working memory (WM capacity depends on the representational precision, as well as its variability from moment to moment. By contrast, visuospatial WM performance in children has been typically indexed by response accuracy—a binary measure that provides less information about precision with which items are stored. Here, we aimed at identifying whether and how children’s WM performance depends on the spatial precision and its variability over time in real-world contexts. Using smartphones, 110 Grade 3 and Grade 4 students performed a spatial WM updating task three times a day in school and at home for four weeks. Measures of spatial precision (i.e., Euclidean distance between presented and reported location were used for hierarchical modeling to estimate variability of spatial precision across different time scales. Results demonstrated considerable within-person variability in spatial precision across items within trials, from trial to trial and from occasion to occasion within days and from day to day. In particular, item-to-item variability was systematically increased with memory load and lowered with higher grade. Further, children with higher precision variability across items scored lower in measures of fluid intelligence. These findings emphasize the important role of transient changes in spatial precision for the development of WM.

  2. Time dependent analysis of assay comparability: a novel approach to understand intra- and inter-site variability over time

    Science.gov (United States)

    Winiwarter, Susanne; Middleton, Brian; Jones, Barry; Courtney, Paul; Lindmark, Bo; Page, Ken M.; Clark, Alan; Landqvist, Claire

    2015-09-01

    We demonstrate here a novel use of statistical tools to study intra- and inter-site assay variability of five early drug metabolism and pharmacokinetics in vitro assays over time. Firstly, a tool for process control is presented. It shows the overall assay variability but allows also the following of changes due to assay adjustments and can additionally highlight other, potentially unexpected variations. Secondly, we define the minimum discriminatory difference/ratio to support projects to understand how experimental values measured at different sites at a given time can be compared. Such discriminatory values are calculated for 3 month periods and followed over time for each assay. Again assay modifications, especially assay harmonization efforts, can be noted. Both the process control tool and the variability estimates are based on the results of control compounds tested every time an assay is run. Variability estimates for a limited set of project compounds were computed as well and found to be comparable. This analysis reinforces the need to consider assay variability in decision making, compound ranking and in silico modeling.

  3. Neuronal variability during handwriting: lognormal distribution.

    Directory of Open Access Journals (Sweden)

    Valery I Rupasov

    Full Text Available We examined time-dependent statistical properties of electromyographic (EMG signals recorded from intrinsic hand muscles during handwriting. Our analysis showed that trial-to-trial neuronal variability of EMG signals is well described by the lognormal distribution clearly distinguished from the Gaussian (normal distribution. This finding indicates that EMG formation cannot be described by a conventional model where the signal is normally distributed because it is composed by summation of many random sources. We found that the variability of temporal parameters of handwriting--handwriting duration and response time--is also well described by a lognormal distribution. Although, the exact mechanism of lognormal statistics remains an open question, the results obtained should significantly impact experimental research, theoretical modeling and bioengineering applications of motor networks. In particular, our results suggest that accounting for lognormal distribution of EMGs can improve biomimetic systems that strive to reproduce EMG signals in artificial actuators.

  4. Broad-Band Variability in Accreting Compact Objects

    Directory of Open Access Journals (Sweden)

    S. Scaringi

    2015-02-01

    Full Text Available Cataclysmic variable stars are in many ways similar to X-ray binaries. Both types of systems possess an accretion disk, which in most cases can reach the surface (or event horizon of the central compact object. The main difference is that the embedded gravitational potential well in X-ray binaries is much deeper than those found in cataclysmic variables. As a result, X-ray binaries emit most of their radiation at X-ray wavelengths, as opposed to cataclysmic variables which emit mostly at optical/ultraviolet wavelengths. Both types of systems display aperiodic broad-band variability which can be associated to the accretion disk. Here, the properties of the observed X-ray variability in XRBs are compared to those observed at optical wavelengths in CVs. In most cases the variability properties of both types of systems are qualitatively similar once the relevant timescales associated with the inner accretion disk regions have been taken into account. The similarities include the observed power spectral density shapes, the rms-flux relation as well as Fourier-dependant time lags. Here a brief overview on these similarities is given, placing them in the context of the fluctuating accretion disk model which seeks to reproduce the observed variability.

  5. Protocol dependence of mechanical properties in granular systems.

    Science.gov (United States)

    Inagaki, S; Otsuki, M; Sasa, S

    2011-11-01

    We study the protocol dependence of the mechanical properties of granular media by means of computer simulations. We control a protocol of realizing disk packings in a systematic manner. In 2D, by keeping material properties of the constituents identical, we carry out compaction with various strain rates. The disk packings exhibit the strain rate dependence of the critical packing fraction above which the pressure becomes non-zero. The observed behavior contrasts with the well-studied jamming transitions for frictionless disk packings. We also observe that the elastic moduli of the disk packings depend on the strain rate logarithmically. Our results suggest that there exists a time-dependent state variable to describe macroscopic material properties of disk packings, which depend on its protocol.

  6. Improved sample size determination for attributes and variables sampling

    International Nuclear Information System (INIS)

    Stirpe, D.; Picard, R.R.

    1985-01-01

    Earlier INMM papers have addressed the attributes/variables problem and, under conservative/limiting approximations, have reported analytical solutions for the attributes and variables sample sizes. Through computer simulation of this problem, we have calculated attributes and variables sample sizes as a function of falsification, measurement uncertainties, and required detection probability without using approximations. Using realistic assumptions for uncertainty parameters of measurement, the simulation results support the conclusions: (1) previously used conservative approximations can be expensive because they lead to larger sample sizes than needed; and (2) the optimal verification strategy, as well as the falsification strategy, are highly dependent on the underlying uncertainty parameters of the measurement instruments. 1 ref., 3 figs

  7. Two-phase strategy of neural control for planar reaching movements: I. XY coordination variability and its relation to end-point variability.

    Science.gov (United States)

    Rand, Miya K; Shimansky, Yury P

    2013-03-01

    A quantitative model of optimal transport-aperture coordination (TAC) during reach-to-grasp movements has been developed in our previous studies. The utilization of that model for data analysis allowed, for the first time, to examine the phase dependence of the precision demand specified by the CNS for neurocomputational information processing during an ongoing movement. It was shown that the CNS utilizes a two-phase strategy for movement control. That strategy consists of reducing the precision demand for neural computations during the initial phase, which decreases the cost of information processing at the expense of lower extent of control optimality. To successfully grasp the target object, the CNS increases precision demand during the final phase, resulting in higher extent of control optimality. In the present study, we generalized the model of optimal TAC to a model of optimal coordination between X and Y components of point-to-point planar movements (XYC). We investigated whether the CNS uses the two-phase control strategy for controlling those movements, and how the strategy parameters depend on the prescribed movement speed, movement amplitude and the size of the target area. The results indeed revealed a substantial similarity between the CNS's regulation of TAC and XYC. First, the variability of XYC within individual trials was minimal, meaning that execution noise during the movement was insignificant. Second, the inter-trial variability of XYC was considerable during the majority of the movement time, meaning that the precision demand for information processing was lowered, which is characteristic for the initial phase. That variability significantly decreased, indicating higher extent of control optimality, during the shorter final movement phase. The final phase was the longest (shortest) under the most (least) challenging combination of speed and accuracy requirements, fully consistent with the concept of the two-phase control strategy. This paper

  8. Soil variability in mountain areas

    OpenAIRE

    Zanini, E.; Freppaz, M.; Stanchi, S.; Bonifacio, E.; Egli, M.

    2015-01-01

    The high spatial variability of soils is a relevant issue at local and global scales, and determines the complexity of soil ecosystem functions and services. This variability derives from strong dependencies of soil ecosystems on parent materials, climate, relief and biosphere, including human impact. Although present in all environments, the interactions of soils with these forming factors are particularly striking in mountain areas.

  9. Polynomial chaos expansion with random and fuzzy variables

    Science.gov (United States)

    Jacquelin, E.; Friswell, M. I.; Adhikari, S.; Dessombz, O.; Sinou, J.-J.

    2016-06-01

    A dynamical uncertain system is studied in this paper. Two kinds of uncertainties are addressed, where the uncertain parameters are described through random variables and/or fuzzy variables. A general framework is proposed to deal with both kinds of uncertainty using a polynomial chaos expansion (PCE). It is shown that fuzzy variables may be expanded in terms of polynomial chaos when Legendre polynomials are used. The components of the PCE are a solution of an equation that does not depend on the nature of uncertainty. Once this equation is solved, the post-processing of the data gives the moments of the random response when the uncertainties are random or gives the response interval when the variables are fuzzy. With the PCE approach, it is also possible to deal with mixed uncertainty, when some parameters are random and others are fuzzy. The results provide a fuzzy description of the response statistical moments.

  10. Results of the study of variables related to tasks of workers of a radioactive facility

    Energy Technology Data Exchange (ETDEWEB)

    Alves, Alice S.; Campos, Daniela; Carneiro, Janete C.G.G., E-mail: alicesante@usp.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2015-07-01

    This paper presents the results of the evaluation study of the association degree between physical risk agent, ionizing radiation, and tasks performed by the occupationally exposed individuals (OEI), in the production of radioisotopes and radiopharmaceuticals of a radioactive facility. Initially, has been performed a qualitative assessment of the workplace, work groups and the processes as well. Starting from the inventoried subjective information, interviews and observations were identified seven homogeneous exposure groups, assuming they receive the same exposure to a range of specific agents. The data were analyzed by means of descriptive statistics with quantitative and qualitative approaches of the variables. In the analysis was used nonparametric tests (Equality of two proportions, Chi-square and Yates correction), descriptive measures of location (mean, median and quartiles) and dispersion (standard deviation and coefficient of variation). A significance level of 5% (p < 0.05) was adopted. The results have shown five risk factors (variables) related to the tasks performance. After the characterization distribution of the relative frequencies, all variables showed a significant degree of association (p < 0.001) to the exposure to ionizing radiation. Descriptive analysis of effective doses received by OEIs (n=102) resulted in the average of 4.06 mSv obtained in 2013 and 3.41 mSv in 2014. The collective doses corresponding to the same year were 414.41 mSv.person and 347.61 mSv.person. The doses values found during the analyzed period are in accordance to the limits established by the current national standards. (author)

  11. Results of the study of variables related to tasks of workers of a radioactive facility

    International Nuclear Information System (INIS)

    Alves, Alice S.; Campos, Daniela; Carneiro, Janete C.G.G.

    2015-01-01

    This paper presents the results of the evaluation study of the association degree between physical risk agent, ionizing radiation, and tasks performed by the occupationally exposed individuals (OEI), in the production of radioisotopes and radiopharmaceuticals of a radioactive facility. Initially, has been performed a qualitative assessment of the workplace, work groups and the processes as well. Starting from the inventoried subjective information, interviews and observations were identified seven homogeneous exposure groups, assuming they receive the same exposure to a range of specific agents. The data were analyzed by means of descriptive statistics with quantitative and qualitative approaches of the variables. In the analysis was used nonparametric tests (Equality of two proportions, Chi-square and Yates correction), descriptive measures of location (mean, median and quartiles) and dispersion (standard deviation and coefficient of variation). A significance level of 5% (p < 0.05) was adopted. The results have shown five risk factors (variables) related to the tasks performance. After the characterization distribution of the relative frequencies, all variables showed a significant degree of association (p < 0.001) to the exposure to ionizing radiation. Descriptive analysis of effective doses received by OEIs (n=102) resulted in the average of 4.06 mSv obtained in 2013 and 3.41 mSv in 2014. The collective doses corresponding to the same year were 414.41 mSv.person and 347.61 mSv.person. The doses values found during the analyzed period are in accordance to the limits established by the current national standards. (author)

  12. Spatio-temporal dependencies between hospital beds, physicians and health expenditure using visual variables and data classification in statistical table

    Science.gov (United States)

    Medyńska-Gulij, Beata; Cybulski, Paweł

    2016-06-01

    This paper analyses the use of table visual variables of statistical data of hospital beds as an important tool for revealing spatio-temporal dependencies. It is argued that some of conclusions from the data about public health and public expenditure on health have a spatio-temporal reference. Different from previous studies, this article adopts combination of cartographic pragmatics and spatial visualization with previous conclusions made in public health literature. While the significant conclusions about health care and economic factors has been highlighted in research papers, this article is the first to apply visual analysis to statistical table together with maps which is called previsualisation.

  13. Spatio-temporal dependencies between hospital beds, physicians and health expenditure using visual variables and data classification in statistical table

    Directory of Open Access Journals (Sweden)

    Medyńska-Gulij Beata

    2016-06-01

    Full Text Available This paper analyses the use of table visual variables of statistical data of hospital beds as an important tool for revealing spatio-temporal dependencies. It is argued that some of conclusions from the data about public health and public expenditure on health have a spatio-temporal reference. Different from previous studies, this article adopts combination of cartographic pragmatics and spatial visualization with previous conclusions made in public health literature. While the significant conclusions about health care and economic factors has been highlighted in research papers, this article is the first to apply visual analysis to statistical table together with maps which is called previsualisation.

  14. The variability of interconnected wind plants

    International Nuclear Information System (INIS)

    Katzenstein, Warren; Fertig, Emily; Apt, Jay

    2010-01-01

    We present the first frequency-dependent analyses of the geographic smoothing of wind power's variability, analyzing the interconnected measured output of 20 wind plants in Texas. Reductions in variability occur at frequencies corresponding to times shorter than ∼24 h and are quantified by measuring the departure from a Kolmogorov spectrum. At a frequency of 2.8x10 -4 Hz (corresponding to 1 h), an 87% reduction of the variability of a single wind plant is obtained by interconnecting 4 wind plants. Interconnecting the remaining 16 wind plants produces only an additional 8% reduction. We use step change analyses and correlation coefficients to compare our results with previous studies, finding that wind power ramps up faster than it ramps down for each of the step change intervals analyzed and that correlation between the power output of wind plants 200 km away is half that of co-located wind plants. To examine variability at very low frequencies, we estimate yearly wind energy production in the Great Plains region of the United States from automated wind observations at airports covering 36 years. The estimated wind power has significant inter-annual variability and the severity of wind drought years is estimated to be about half that observed nationally for hydroelectric power.

  15. Variables associated with active spondylolysis.

    Science.gov (United States)

    Gregg, Chris D; Dean, Sarah; Schneiders, Anthony G

    2009-11-01

    Retrospective non-experimental study. To investigate variables associated with active spondylolysis. A retrospective study audited clinical data over a two year period from patients with suspected spondylolysis that were referred for a SPECT bone scan. Six exploratory variables were identified and analysed using uni- and multi-variate regression from 82 patient records to determine the association between symptomatic, physical and demographic characteristics, and the presence of an active spondylolysis. Tertiary level multidisciplinary private practice sports medicine clinic. All patients with low back pain that required a SPECT bone scan to confirm suspected spondylolysis. 82 subjects were included in the final sample group. The six exploratory variables included Age, Gender, Injury duration, Injury onset, Sports participation and the result of the Single Leg Hyperextension Test. The dependent outcome variable was the result of the SPECT bone scan (scan-positive or scan-negative). Adolescent males had a higher incidence of spondylolysis detected by SPECT bone scan compared to other patients and a statistically significant association was demonstrated for both age (p=0.01) and gender (p=0.01). Subjects with an active spondylolysis were nearly five times more likely to be male and aged less than 20 years. Furthermore, the likelihood ratio indicated that adolescent males with suspected spondylolysis were three and a half times more likely to have a positive bone scan result. The Single Leg Hyperextension Test did not demonstrate a statistically significant association with spondylolysis (p=0.47). Clinicians assessing for a predisposition to the development of spondylolysis should consider the gender and age of the patient and not rely on the predictive ability of the Single Leg Hyperextension Test.

  16. Results of Propellant Mixing Variable Study Using Precise Pressure-Based Burn Rate Calculations

    Science.gov (United States)

    Stefanski, Philip L.

    2014-01-01

    A designed experiment was conducted in which three mix processing variables (pre-curative addition mix temperature, pre-curative addition mixing time, and mixer speed) were varied to estimate their effects on within-mix propellant burn rate variability. The chosen discriminator for the experiment was the 2-inch diameter by 4-inch long (2x4) Center-Perforated (CP) ballistic evaluation motor. Motor nozzle throat diameters were sized to produce a common targeted chamber pressure. Initial data analysis did not show a statistically significant effect. Because propellant burn rate must be directly related to chamber pressure, a method was developed that showed statistically significant effects on chamber pressure (either maximum or average) by adjustments to the process settings. Burn rates were calculated from chamber pressures and these were then normalized to a common pressure for comparative purposes. The pressure-based method of burn rate determination showed significant reduction in error when compared to results obtained from the Brooks' modification of the propellant web-bisector burn rate determination method. Analysis of effects using burn rates calculated by the pressure-based method showed a significant correlation of within-mix burn rate dispersion to mixing duration and the quadratic of mixing duration. The findings were confirmed in a series of mixes that examined the effects of mixing time on burn rate variation, which yielded the same results.

  17. Regional impacts of ocean color on tropical Pacific variability

    Directory of Open Access Journals (Sweden)

    W. Anderson

    2009-08-01

    Full Text Available The role of the penetration length scale of shortwave radiation into the surface ocean and its impact on tropical Pacific variability is investigated with a fully coupled ocean, atmosphere, land and ice model. Previous work has shown that removal of all ocean color results in a system that tends strongly towards an El Niño state. Results from a suite of surface chlorophyll perturbation experiments show that the mean state and variability of the tropical Pacific is highly sensitive to the concentration and distribution of ocean chlorophyll. Setting the near-oligotrophic regions to contain optically pure water warms the mean state and suppresses variability in the western tropical Pacific. Doing the same above the shadow zones of the tropical Pacific also warms the mean state but enhances the variability. It is shown that increasing penetration can both deepen the pycnocline (which tends to damp El Niño while shifting the mean circulation so that the wind response to temperature changes is altered. Depending on what region is involved this change in the wind stress can either strengthen or weaken ENSO variability.

  18. Variability in large-scale wind power generation: Variability in large-scale wind power generation

    Energy Technology Data Exchange (ETDEWEB)

    Kiviluoma, Juha [VTT Technical Research Centre of Finland, Espoo Finland; Holttinen, Hannele [VTT Technical Research Centre of Finland, Espoo Finland; Weir, David [Energy Department, Norwegian Water Resources and Energy Directorate, Oslo Norway; Scharff, Richard [KTH Royal Institute of Technology, Electric Power Systems, Stockholm Sweden; Söder, Lennart [Royal Institute of Technology, Electric Power Systems, Stockholm Sweden; Menemenlis, Nickie [Institut de recherche Hydro-Québec, Montreal Canada; Cutululis, Nicolaos A. [DTU, Wind Energy, Roskilde Denmark; Danti Lopez, Irene [Electricity Research Centre, University College Dublin, Dublin Ireland; Lannoye, Eamonn [Electric Power Research Institute, Palo Alto California USA; Estanqueiro, Ana [LNEG, Laboratorio Nacional de Energia e Geologia, UESEO, Lisbon Spain; Gomez-Lazaro, Emilio [Renewable Energy Research Institute and DIEEAC/EDII-AB, Castilla-La Mancha University, Albacete Spain; Zhang, Qin [State Grid Corporation of China, Beijing China; Bai, Jianhua [State Grid Energy Research Institute Beijing, Beijing China; Wan, Yih-Huei [National Renewable Energy Laboratory, Transmission and Grid Integration Group, Golden Colorado USA; Milligan, Michael [National Renewable Energy Laboratory, Transmission and Grid Integration Group, Golden Colorado USA

    2015-10-25

    The paper demonstrates the characteristics of wind power variability and net load variability in multiple power systems based on real data from multiple years. Demonstrated characteristics include probability distribution for different ramp durations, seasonal and diurnal variability and low net load events. The comparison shows regions with low variability (Sweden, Spain and Germany), medium variability (Portugal, Ireland, Finland and Denmark) and regions with higher variability (Quebec, Bonneville Power Administration and Electric Reliability Council of Texas in North America; Gansu, Jilin and Liaoning in China; and Norway and offshore wind power in Denmark). For regions with low variability, the maximum 1 h wind ramps are below 10% of nominal capacity, and for regions with high variability, they may be close to 30%. Wind power variability is mainly explained by the extent of geographical spread, but also higher capacity factor causes higher variability. It was also shown how wind power ramps are autocorrelated and dependent on the operating output level. When wind power was concentrated in smaller area, there were outliers with high changes in wind output, which were not present in large areas with well-dispersed wind power.

  19. On the Temporal Variability of Low-Mode Internal Tides in the Deep Ocean

    Science.gov (United States)

    Ray, Richard D.; Zaron, E. D.

    2010-01-01

    In situ measurements of internal tides are typically characterized by high temporal variability, with strong dependence on stratification, mesoscale eddies, and background currents commonly observed. Thus, it is surprising to find phase-locked internal tides detectable by satellite altimetry. An important question is how much tidal variability is missed by altimetry. We address this question in several ways. We subset the altimetry by season and find only very small changes -- an important exception being internal tides in the South China Sea where we observe strong seasonal dependence. A wavenumber-domain analysis confirms that throughout most of the global ocean there is little temporal variability in altimetric internal-tide signals, at least in the first baroclinic mode, which is the mode that dominates surface elevation. The analysis shows higher order modes to be significantly more variable. The results of this study have important practical implications for the anticipated SWOT wide-swath altimeter mission, for which removal of internal tide signals is critical for observing non-tidal submesoscale phenomena.

  20. Dynamical invariants for variable quadratic Hamiltonians

    International Nuclear Information System (INIS)

    Suslov, Sergei K

    2010-01-01

    We consider linear and quadratic integrals of motion for general variable quadratic Hamiltonians. Fundamental relations between the eigenvalue problem for linear dynamical invariants and solutions of the corresponding Cauchy initial value problem for the time-dependent Schroedinger equation are emphasized. An eigenfunction expansion of the solution of the initial value problem is also found. A nonlinear superposition principle for generalized Ermakov systems is established as a result of decomposition of the general quadratic invariant in terms of the linear ones.

  1. Incorporation of gene-specific variability improves expression analysis using high-density DNA microarrays

    Directory of Open Access Journals (Sweden)

    Spitznagel Edward

    2003-11-01

    Full Text Available Abstract Background The assessment of data reproducibility is essential for application of microarray technology to exploration of biological pathways and disease states. Technical variability in data analysis largely depends on signal intensity. Within that context, the reproducibility of individual probe sets has not been hitherto addressed. Results We used an extraordinarily large replicate data set derived from human placental trophoblast to analyze probe-specific contribution to variability of gene expression. We found that signal variability, in addition to being signal-intensity dependant, is probe set-specific. Importantly, we developed a novel method to quantify the contribution of this probe set-specific variability. Furthermore, we devised a formula that incorporates a priori-computed, replicate-based information on probe set- and intensity-specific variability in determination of expression changes even without technical replicates. Conclusion The strategy of incorporating probe set-specific variability is superior to analysis based on arbitrary fold-change thresholds. We recommend its incorporation to any computation of gene expression changes using high-density DNA microarrays. A Java application implementing our T-score is available at http://www.sadovsky.wustl.edu/tscore.html.

  2. Cryotherapy, Sensation, and Isometric-Force Variability

    Science.gov (United States)

    Denegar, Craig R.; Buckley, William E.; Newell, Karl M.

    2003-01-01

    Objective: To determine the changes in sensation of pressure, 2-point discrimination, and submaximal isometric-force production variability due to cryotherapy. Design and Setting: Sensation was assessed using a 2 × 2 × 2 × 3 repeated-measures factorial design, with treatment (ice immersion or control), limb (right or left), digit (finger or thumb), and sensation test time (baseline, posttreatment, or postisometric-force trials) as independent variables. Dependent variables were changes in sensation of pressure and 2-point discrimination. Isometric-force variability was tested with a 2 × 2 × 3 repeated-measures factorial design. Treatment condition (ice immersion or control), limb (right or left), and percentage (10, 25, or 40) of maximal voluntary isometric contraction (MVIC) were the independent variables. The dependent variables were the precision or variability (the standard deviation of mean isometric force) and the accuracy or targeting error (the root mean square error) of the isometric force for each percentage of MVIC. Subjects: Fifteen volunteer college students (8 men, 7 women; age = 22 ± 3 years; mass = 72 ± 21.9 kg; height = 183.4 ± 11.6 cm). Measurements: We measured sensation in the distal palmar aspect of the index finger and thumb. Sensation of pressure and 2-point discrimination were measured before treatment (baseline), after treatment (15 minutes of ice immersion or control), and at the completion of isometric testing (final). Variability (standard deviation of mean isometric force) of the submaximal isometric finger forces was measured by having the subjects exert a pinching force with the thumb and index finger for 30 seconds. Subjects performed the pinching task at the 3 submaximal levels of MVIC (10%, 25%, and 40%), with the order of trials assigned randomly. The subjects were given a target representing the submaximal percentage of MVIC and visual feedback of the force produced as they pinched the testing device. The force exerted

  3. [Hydrologic variability and sensitivity based on Hurst coefficient and Bartels statistic].

    Science.gov (United States)

    Lei, Xu; Xie, Ping; Wu, Zi Yi; Sang, Yan Fang; Zhao, Jiang Yan; Li, Bin Bin

    2018-04-01

    Due to the global climate change and frequent human activities in recent years, the pure stochastic components of hydrological sequence is mixed with one or several of the variation ingredients, including jump, trend, period and dependency. It is urgently needed to clarify which indices should be used to quantify the degree of their variability. In this study, we defined the hydrological variability based on Hurst coefficient and Bartels statistic, and used Monte Carlo statistical tests to test and analyze their sensitivity to different variants. When the hydrological sequence had jump or trend variation, both Hurst coefficient and Bartels statistic could reflect the variation, with the Hurst coefficient being more sensitive to weak jump or trend variation. When the sequence had period, only the Bartels statistic could detect the mutation of the sequence. When the sequence had a dependency, both the Hurst coefficient and the Bartels statistics could reflect the variation, with the latter could detect weaker dependent variations. For the four variations, both the Hurst variability and Bartels variability increased with the increases of variation range. Thus, they could be used to measure the variation intensity of the hydrological sequence. We analyzed the temperature series of different weather stations in the Lancang River basin. Results showed that the temperature of all stations showed the upward trend or jump, indicating that the entire basin had experienced warming in recent years and the temperature variability in the upper and lower reaches was much higher. This case study showed the practicability of the proposed method.

  4. [Inter-and intra-operator variability in the analysis of semen parameters: results from a quality control program].

    Science.gov (United States)

    Daoud, Salima; Chakroun-Feki, Nozha; Sellami, Afifa; Ammar-Keskes, Leila; Rebai, Tarek

    2016-01-01

    Semen analysis is a key part of male infertility investigation. The necessity of quality management implementation in the andrology laboratory has been recognized in order to ensure the reliability of its results. The aim of this study was to evaluate intra- and inter-individual variability in the assessment of semen parameters in our laboratory through a quality control programme. Four participants from the laboratory with different experience levels have participated in this study. Semen samples of varying quality were assessed for sperm motility, concentration and morphology and the results were used to evaluate inter-participant variability. In addition, replicates of each semen sample were analyzed to determine intra-individual variability for semen parameters analysis. The average values of inter-participant coefficients of variation for sperm motility, concentration and morphology were 12.8%, 19.8% and 48.9% respectively. The mean intra-participant coefficients of variation were, respectively, 6.9%, 12.3% and 42.7% for sperm motility, concentration and morphology. Despite some random errors of under- or overestimation, the overall results remained within the limits of acceptability for all participants. Sperm morphology assessment was particularly influenced by the participant's level of experience. The present data emphasize the need for appropriate training of the laboratory staff and for regular participation in internal quality control programmes in order to improve the reliability of laboratory results.

  5. Identifying Midshipmen for Academic Assistance Using Entry Variables

    National Research Council Canada - National Science Library

    Watson, Arthur

    2001-01-01

    .... Categorical values from the Learning and Study Strategies Inventory (LASSI), SAT scores and high school rank were incorporated as independent variables in a linear regression model with dependent variable Cumulative Quality Point Rating (CQPR...

  6. Chaotic behaviour of a pendulum with variable length

    Energy Technology Data Exchange (ETDEWEB)

    Bartuccelli, M; Christiansen, P L; Muto, V; Soerensen, M P; Pedersen, N F

    1987-08-01

    The Melnikov function for the prediction of Smale horseshoe chaos is applied to a driven damped pendulum with variable length. Depending on the parameters, it is shown that this dynamical system undertakes heteroclinic bifurcations which are the source of the unstable chaotic motion. The analytical results are illustrated by new numerical simulations. Furthermore, using the averaging theorem, the stability of the subharmonics is studied.

  7. Discriminant Profile of Young Internet Dependents: The Role of Family Relationships

    Directory of Open Access Journals (Sweden)

    Michele Terres-Trindade

    2015-12-01

    Full Text Available AbstractInternational studies have shown effects of family relations on Internet addiction in young people. This research aimed to outline a discriminant profile of young people classified as dependent and not dependent on the Internet regarding to socio-biodemographic variables to parenting practices, parent-child conflict and interparental conflict. The sample consisted of 200 students (152 girls and 48 boys, between 15 and 24 years of age, 85.5% reside in Rio Grande do Sul and 14.5% in other Brazilian states. Participants responded individually to the protocol available online. The results showed that interparental conflict, parent-child conflict and the educational practice of supervision of paternal behavior discriminate dependents on Internet. The educational practice of maternal emotional support was the only discriminating variable for non-dependents. These national findings corroborate the international context studies and reinforce the importance of including the family in promotion and prevention of mental health of young people.

  8. How Robust Is Linear Regression with Dummy Variables?

    Science.gov (United States)

    Blankmeyer, Eric

    2006-01-01

    Researchers in education and the social sciences make extensive use of linear regression models in which the dependent variable is continuous-valued while the explanatory variables are a combination of continuous-valued regressors and dummy variables. The dummies partition the sample into groups, some of which may contain only a few observations.…

  9. Directional Dependence in Developmental Research

    Science.gov (United States)

    von Eye, Alexander; DeShon, Richard P.

    2012-01-01

    In this article, we discuss and propose methods that may be of use to determine direction of dependence in non-normally distributed variables. First, it is shown that standard regression analysis is unable to distinguish between explanatory and response variables. Then, skewness and kurtosis are discussed as tools to assess deviation from…

  10. Assessing variability in results in systematic reviews of diagnostic studies

    NARCIS (Netherlands)

    Naaktgeboren, Christiana A; Ochodo, Eleanor A; Van Enst, Wynanda A; de Groot, Joris A H; Hooft, Lotty; Leeflang, Mariska M G; Bossuyt, Patrick M; Moons, Karel G M; Reitsma, Johannes B

    2016-01-01

    BACKGROUND: To describe approaches used in systematic reviews of diagnostic test accuracy studies for assessing variability in estimates of accuracy between studies and to provide guidance in this area. METHODS: Meta-analyses of diagnostic test accuracy studies published between May and September

  11. Estimation of genetic variability and heritability of wheat agronomic traits resulted from some gamma rays irradiation techniques

    International Nuclear Information System (INIS)

    Wijaya Murti Indriatama; Trikoesoemaningtyas; Syarifah Iis Aisyah; Soeranto Human

    2016-01-01

    Gamma irradiation techniques have significant effect on frequency and spectrum of macro-mutation but the study of its effect on micro-mutation that related to genetic variability on mutated population is very limited. The aim of this research was to study the effect of gamma irradiation techniques on genetic variability and heritability of wheat agronomic characters at M2 generation. This research was conducted from July to November 2014, at Cibadak experimental station, Indonesian Center for Agricultural Biotechnology and Genetic Resources Research and Development, Ministry of Agriculture. Three introduced wheat breeding lines (F-44, Kiran-95 & WL-711) were treated by 3 gamma irradiation techniques (acute, fractionated and intermittent). M1 generation of combination treatments were planted and harvested its spike individually per plants. As M2 generation, seeds of 75 M1 spike were planted at the field with one row one spike method and evaluated on the agronomic characters and its genetic components. The used of gamma irradiation techniques decreased mean but increased range values of agronomic traits in M2 populations. Fractionated irradiation induced higher mean and wider range on spike length and number of spike let per spike than other irradiation techniques. Fractionated and intermittent irradiation resulted greater variability of grain weight per plant than acute irradiation. The number of tillers, spike weight, grain weight per spike and grain weight per plant on M2 population resulted from induction of three gamma irradiation techniques have high estimated heritability and broad sense of genetic variability coefficient values. The three gamma irradiation techniques increased genetic variability of agronomic traits on M2 populations, except plant height. (author)

  12. Impact of High-Cut-Off Dialysis on Renal Recovery in Dialysis-Dependent Multiple Myeloma Patients: Results from a Case-Control Study.

    Directory of Open Access Journals (Sweden)

    Hans U Gerth

    Full Text Available High-cut-off hemodialysis (HCO-HD can effectively reduce high concentrations of circulating serum free light chains (sFLC in patients with dialysis-dependent acute kidney injury (AKI due to multiple myeloma (MM. Therefore, the aim of this study was to analyze renal recovery in a retrospective single-center cohort of dialysis-dependent MM patients treated with either conventional HD (conv. HD or HCO-HD.The final cohort consisted of 59 patients treated with HCO-HD (n = 42 or conv. HD (n = 17. A sustained sFLC response was detected in a significantly higher proportion of HCO-HD patients (83.3% compared with conv. HD patients (29.4%; p = 0.007. The median duration of sFLC required to reach values <1000 mg/l was 14.5 days in the HCO-HD group and 36 days in the conv. HD group. The corresponding rates of renal recovery were 64.3% and 29.4%, respectively (chi-squared test, p = 0.014. Multivariate regression and decision tree analysis (recursive partitioning revealed HCO-HD (adjusted odds ratio [OR] 6.1 [95% confidence interval (CI 1.5-24.5], p = 0.011 and low initial uric acid values (adjusted OR 1.3 [95%CI 1.0-1.7], p = 0.045 as independent and paramount variables associated with a favorable renal outcome.In summary, the results from this retrospective case-control study suggest in addition to novel agent-based chemotherapy a benefit of HCO-HD in sFLC removal and renal outcome in dialysis-dependent AKI secondary to MM. This finding was especially pertinent in patients with low initial uric acid values, resulting in a promising renal recovery rate of 71.9%. Further prospective studies are warranted.

  13. Analysis models for variables associated with breastfeeding duration

    Directory of Open Access Journals (Sweden)

    Edson Theodoro dos S. Neto

    2013-09-01

    Full Text Available OBJECTIVE To analyze the factors associated with breastfeeding duration by two statistical models. METHODS A population-based cohort study was conducted with 86 mothers and newborns from two areas primary covered by the National Health System, with high rates of infant mortality in Vitória, Espírito Santo, Brazil. During 30 months, 67 (78% children and mothers were visited seven times at home by trained interviewers, who filled out survey forms. Data on food and sucking habits, socioeconomic and maternal characteristics were collected. Variables were analyzed by Cox regression models, considering duration of breastfeeding as the dependent variable, and logistic regression (dependent variables, was the presence of a breastfeeding child in different post-natal ages. RESULTS In the logistic regression model, the pacifier sucking (adjusted Odds Ratio: 3.4; 95%CI 1.2-9.55 and bottle feeding (adjusted Odds Ratio: 4.4; 95%CI 1.6-12.1 increased the chance of weaning a child before one year of age. Variables associated to breastfeeding duration in the Cox regression model were: pacifier sucking (adjusted Hazard Ratio 2.0; 95%CI 1.2-3.3 and bottle feeding (adjusted Hazard Ratio 2.0; 95%CI 1.2-3.5. However, protective factors (maternal age and family income differed between both models. CONCLUSIONS Risk and protective factors associated with cessation of breastfeeding may be analyzed by different models of statistical regression. Cox Regression Models are adequate to analyze such factors in longitudinal studies.

  14. Density dependence and climate effects in Rocky Mountain elk: an application of regression with instrumental variables for population time series with sampling error.

    Science.gov (United States)

    Creel, Scott; Creel, Michael

    2009-11-01

    1. Sampling error in annual estimates of population size creates two widely recognized problems for the analysis of population growth. First, if sampling error is mistakenly treated as process error, one obtains inflated estimates of the variation in true population trajectories (Staples, Taper & Dennis 2004). Second, treating sampling error as process error is thought to overestimate the importance of density dependence in population growth (Viljugrein et al. 2005; Dennis et al. 2006). 2. In ecology, state-space models are used to account for sampling error when estimating the effects of density and other variables on population growth (Staples et al. 2004; Dennis et al. 2006). In econometrics, regression with instrumental variables is a well-established method that addresses the problem of correlation between regressors and the error term, but requires fewer assumptions than state-space models (Davidson & MacKinnon 1993; Cameron & Trivedi 2005). 3. We used instrumental variables to account for sampling error and fit a generalized linear model to 472 annual observations of population size for 35 Elk Management Units in Montana, from 1928 to 2004. We compared this model with state-space models fit with the likelihood function of Dennis et al. (2006). We discuss the general advantages and disadvantages of each method. Briefly, regression with instrumental variables is valid with fewer distributional assumptions, but state-space models are more efficient when their distributional assumptions are met. 4. Both methods found that population growth was negatively related to population density and winter snow accumulation. Summer rainfall and wolf (Canis lupus) presence had much weaker effects on elk (Cervus elaphus) dynamics [though limitation by wolves is strong in some elk populations with well-established wolf populations (Creel et al. 2007; Creel & Christianson 2008)]. 5. Coupled with predictions for Montana from global and regional climate models, our results

  15. Oracle Efficient Variable Selection in Random and Fixed Effects Panel Data Models

    DEFF Research Database (Denmark)

    Kock, Anders Bredahl

    This paper generalizes the results for the Bridge estimator of Huang et al. (2008) to linear random and fixed effects panel data models which are allowed to grow in both dimensions. In particular we show that the Bridge estimator is oracle efficient. It can correctly distinguish between relevant...... and irrelevant variables and the asymptotic distribution of the estimators of the coefficients of the relevant variables is the same as if only these had been included in the model, i.e. as if an oracle had revealed the true model prior to estimation. In the case of more explanatory variables than observations......, we prove that the Marginal Bridge estimator can asymptotically correctly distinguish between relevant and irrelevant explanatory variables. We do this without restricting the dependence between covariates and without assuming sub Gaussianity of the error terms thereby generalizing the results...

  16. EXECUTIVE DYSFUNCTION IN ALCOHOL DEPENDENT INDIVIDUALS: A CASE CONTROL STUDY

    Directory of Open Access Journals (Sweden)

    Neethi Valsan

    2016-06-01

    Full Text Available BACKGROUND The use of alcohol is increasingly prevalent in our country. Being a neurotoxin, it tends to affect elective mental capacities. Frontal lobe is found to be most affected by chronic alcohol use. AIM To study the executive functions in alcohol dependent individuals and to determine any relationship with alcohol intake variables. MATERIALS AND METHODS 30 recently detoxified alcohol dependent individuals attending the De-addiction Clinic of Medical College, Kottayam, was compared to 30 controls on four tests of executive functions, namely, Controlled Word Association Test, Trail Making Test, Stroop Test, and Wisconsin Card Sorting Test. Statistical analysis of the data has been done using the Statistical Package for Social Sciences (SPSS Windows version 10. RESULTS Executive function was significantly impaired in the alcohol dependent individuals when compared to normal controls in all the four tests. On analysing the effect of drinking variables on executive functioning, the performance of patients is seen to improve with abstinence in Stroop. Those with a positive family history of ADS in the first degree relatives produced fewer words in verbal fluency. CONCLUSION As the executive impairment remains more or less stable irrespective to the chronicity or amount of alcohol use, it could be assumed that the executive dysfunction observed is a trait marker rather than a state dependent variable.

  17. Modeling Short-Range Soil Variability and its Potential Use in Variable-Rate Treatment of Experimental Plots

    Directory of Open Access Journals (Sweden)

    A Moameni

    2011-02-01

    Full Text Available Abstract In Iran, the experimental plots under fertilizer trials are managed in such a way that the whole plot area uniformly receives agricultural inputs. This could lead to biased research results and hence to suppressing of the efforts made by the researchers. This research was conducted in a selected site belonging to the Gonbad Agricultural Research Station, located in the semiarid region, northeastern Iran. The aim was to characterize the short-range spatial variability of the inherent and management-depended soil properties and to determine if this variation is large and can be managed at practical scales. The soils were sampled using a grid 55 m apart. In total, 100 composite soil samples were collected from topsoil (0-30 cm and were analyzed for calcium carbonate equivalent, organic carbon, clay, available phosphorus, available potassium, iron, copper, zinc and manganese. Descriptive statistics were applied to check data trends. Geostatistical analysis was applied to variography, model fitting and contour mapping. Sampling at 55 m made it possible to split the area of the selected experimental plot into relatively uniform areas that allow application of agricultural inputs with variable rates. Keywords: Short-range soil variability, Within-field soil variability, Interpolation, Precision agriculture, Geostatistics

  18. Efficiency of a new internal combustion engine concept with variable piston motion

    Directory of Open Access Journals (Sweden)

    Dorić Jovan Ž.

    2014-01-01

    Full Text Available This paper presents simulation of working process in a new IC engine concept. The main feature of this new IC engine concept is the realization of variable movement of the piston. With this unconventional piston movement it is easy to provide variable compression ratio, variable displacement and combustion during constant volume. These advantages over standard piston mechanism are achieved through synthesis of the two pairs of non-circular gears. Presented mechanism is designed to obtain a specific motion law which provides better fuel consumption of IC engines. For this paper Ricardo/WAVE software was used, which provides a fully integrated treatment of time-dependent fluid dynamics and thermodynamics by means of onedimensional formulation. The results obtained herein include the efficiency characteristic of this new heat engine concept. The results show that combustion during constant volume, variable compression ratio and variable displacement have significant impact on improvement of fuel consumption.

  19. Investigation of load reduction for a variable speed, variable pitch, and variable coning wind turbine

    Energy Technology Data Exchange (ETDEWEB)

    Pierce, K. [Univ. of Utah, Salt Lake City, UT (United States)

    1997-12-31

    A two bladed, variable speed and variable pitch wind turbine was modeled using ADAMS{reg_sign} to evaluate load reduction abilities of a variable coning configuration as compared to a teetered rotor, and also to evaluate control methods. The basic dynamic behavior of the variable coning turbine was investigated and compared to the teetered rotor under constant wind conditions as well as turbulent wind conditions. Results indicate the variable coning rotor has larger flap oscillation amplitudes and much lower root flap bending moments than the teetered rotor. Three methods of control were evaluated for turbulent wind simulations. These were a standard IPD control method, a generalized predictive control method, and a bias estimate control method. Each control method was evaluated for both the variable coning configuration and the teetered configuration. The ability of the different control methods to maintain the rotor speed near the desired set point is evaluated from the RMS error of rotor speed. The activity of the control system is evaluated from cycles per second of the blade pitch angle. All three of the methods were found to produce similar results for the variable coning rotor and the teetered rotor, as well as similar results to each other.

  20. Dynamic Dependence and Diversification in Corporate Credit

    DEFF Research Database (Denmark)

    Christoffersen, Peter; Jacobs, Kris; Jin, Xisong

    2018-01-01

    We characterize dependence in corporate credit and equity returns for 215 firms using a new class of large-scale dynamic copula models. Copula dependence and especially tail dependence are highly variable and persistent, increase significantly in the financial crisis, and have remained high since...

  1. The effects of spatial autoregressive dependencies on inference in ordinary least squares: a geometric approach

    Science.gov (United States)

    Smith, Tony E.; Lee, Ka Lok

    2012-01-01

    There is a common belief that the presence of residual spatial autocorrelation in ordinary least squares (OLS) regression leads to inflated significance levels in beta coefficients and, in particular, inflated levels relative to the more efficient spatial error model (SEM). However, our simulations show that this is not always the case. Hence, the purpose of this paper is to examine this question from a geometric viewpoint. The key idea is to characterize the OLS test statistic in terms of angle cosines and examine the geometric implications of this characterization. Our first result is to show that if the explanatory variables in the regression exhibit no spatial autocorrelation, then the distribution of test statistics for individual beta coefficients in OLS is independent of any spatial autocorrelation in the error term. Hence, inferences about betas exhibit all the optimality properties of the classic uncorrelated error case. However, a second more important series of results show that if spatial autocorrelation is present in both the dependent and explanatory variables, then the conventional wisdom is correct. In particular, even when an explanatory variable is statistically independent of the dependent variable, such joint spatial dependencies tend to produce "spurious correlation" that results in over-rejection of the null hypothesis. The underlying geometric nature of this problem is clarified by illustrative examples. The paper concludes with a brief discussion of some possible remedies for this problem.

  2. EVIDENCE FOR DYNAMICAL CHANGES IN A TRANSITIONAL PROTOPLANETARY DISK WITH MID-INFRARED VARIABILITY

    International Nuclear Information System (INIS)

    Muzerolle, James; Flaherty, Kevin; Balog, Zoltan; Smith, Paul S.; Rieke, George H.; Furlan, Elise; Allen, Lori; Muench, August; Calvet, Nuria; D'Alessio, Paola; Megeath, S. Thomas; Sherry, William H.

    2009-01-01

    We present multi-epoch Spitzer Space Telescope observations of the transitional disk LRLL 31 in the 2-3 Myr old star-forming region IC 348. Our measurements show remarkable mid-infrared variability on timescales as short as one week. The infrared continuum emission exhibits systematic wavelength-dependent changes that suggest corresponding dynamical changes in the inner disk structure and variable shadowing of outer disk material. We propose several possible sources for the structural changes, including a variable accretion rate or a stellar or planetary companion embedded in the disk. Our results indicate that variability studies in the infrared can provide important new constraints on protoplanetary disk behavior.

  3. Standardizing effect size from linear regression models with log-transformed variables for meta-analysis.

    Science.gov (United States)

    Rodríguez-Barranco, Miguel; Tobías, Aurelio; Redondo, Daniel; Molina-Portillo, Elena; Sánchez, María José

    2017-03-17

    Meta-analysis is very useful to summarize the effect of a treatment or a risk factor for a given disease. Often studies report results based on log-transformed variables in order to achieve the principal assumptions of a linear regression model. If this is the case for some, but not all studies, the effects need to be homogenized. We derived a set of formulae to transform absolute changes into relative ones, and vice versa, to allow including all results in a meta-analysis. We applied our procedure to all possible combinations of log-transformed independent or dependent variables. We also evaluated it in a simulation based on two variables either normally or asymmetrically distributed. In all the scenarios, and based on different change criteria, the effect size estimated by the derived set of formulae was equivalent to the real effect size. To avoid biased estimates of the effect, this procedure should be used with caution in the case of independent variables with asymmetric distributions that significantly differ from the normal distribution. We illustrate an application of this procedure by an application to a meta-analysis on the potential effects on neurodevelopment in children exposed to arsenic and manganese. The procedure proposed has been shown to be valid and capable of expressing the effect size of a linear regression model based on different change criteria in the variables. Homogenizing the results from different studies beforehand allows them to be combined in a meta-analysis, independently of whether the transformations had been performed on the dependent and/or independent variables.

  4. Data interpolation for vibration diagnostics using two-variable correlations

    International Nuclear Information System (INIS)

    Branagan, L.

    1991-01-01

    This paper reports that effective machinery vibration diagnostics require a clear differentiation between normal vibration changes caused by plant process conditions and those caused by degradation. The normal relationship between vibration and a process parameter can be quantified by developing the appropriate correlation. The differences in data acquisition requirements between dynamic signals (vibration spectra) and static signals (pressure, temperature, etc.) result in asynchronous data acquisition; the development of any correlation must then be based on some form of interpolated data. This interpolation can reproduce or distort the original measured quantity depending on the characteristics of the data and the interpolation technique. Relevant data characteristics, such as acquisition times, collection cycle times, compression method, storage rate, and the slew rate of the measured variable, are dependent both on the data handling and on the measured variable. Linear and staircase interpolation, along with the use of clustering and filtering, provide the necessary options to develop accurate correlations. The examples illustrate the appropriate application of these options

  5. Continuous variable quantum key distribution with modulated entangled states

    DEFF Research Database (Denmark)

    Madsen, Lars S; Usenko, Vladyslav C.; Lassen, Mikael

    2012-01-01

    Quantum key distribution enables two remote parties to grow a shared key, which they can use for unconditionally secure communication over a certain distance. The maximal distance depends on the loss and the excess noise of the connecting quantum channel. Several quantum key distribution schemes...... based on coherent states and continuous variable measurements are resilient to high loss in the channel, but are strongly affected by small amounts of channel excess noise. Here we propose and experimentally address a continuous variable quantum key distribution protocol that uses modulated fragile...... entangled states of light to greatly enhance the robustness to channel noise. We experimentally demonstrate that the resulting quantum key distribution protocol can tolerate more noise than the benchmark set by the ideal continuous variable coherent state protocol. Our scheme represents a very promising...

  6. Origins of intersubject variability of blood oxygenation level dependent and arterial spin labeling fMRI: implications for quantification of brain activity.

    Science.gov (United States)

    Gaxiola-Valdez, Ismael; Goodyear, Bradley G

    2012-12-01

    Accurate localization of brain activity using blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging (fMRI) has been challenged because of the large BOLD signal within distal veins. Arterial spin labeling (ASL) techniques offer greater sensitivity to the microvasculature but possess low temporal resolution and limited brain coverage. In this study, we show that the physiological origins of BOLD and ASL depend on whether percent change or statistical significance is being considered. For BOLD and ASL fMRI data collected during a simple unilateral hand movement task, we found that in the area of the contralateral motor cortex the centre of gravity (CoG) of the intersubject coefficient of variation (CV) of BOLD fMRI was near the brain surface for percent change in signal, whereas the CoG of the intersubject CV for Z-score was in close proximity of sites of brain activity for both BOLD and ASL. These findings suggest that intersubject variability of BOLD percent change is vascular in origin, whereas the origin of inter-subject variability of Z-score is neuronal for both BOLD and ASL. For longer duration tasks (12 s or greater), however, there was a significant correlation between BOLD and ASL percent change, which was not evident for short duration tasks (6 s). These findings suggest that analyses directly comparing percent change in BOLD signal between pre-defined regions of interest using short duration stimuli, as for example in event-related designs, may be heavily weighted by large-vessel responses rather than neuronal responses. Copyright © 2012 Elsevier Inc. All rights reserved.

  7. Effect of short-term heart rate variability biofeedback on long-term abstinence in alcohol dependent patients - a one-year follow-up.

    Science.gov (United States)

    Penzlin, Ana Isabel; Barlinn, Kristian; Illigens, Ben Min-Woo; Weidner, Kerstin; Siepmann, Martin; Siepmann, Timo

    2017-09-06

    A randomized controlled study (RCT) recently showed that short-term heart rate variability (HRV) biofeedback in addition to standard rehabilitation care for alcohol dependence can reduce craving, anxiety and improve cardiovascular autonomic function. In this one-year follow-up study we aimed to explore whether completion of 2-week HRV-Biofeedback training is associated with long-term abstinence. Furthermore, we sought to identify potential predictors of post-treatment abstinence. We conducted a survey on abstinence in patients with alcohol dependence 1 year after completion of an RCT comparing HRV-biofeedback in addition to inpatient rehabilitation treatment alone (controls). Abstinence rates were compared and analysed for association with demographic data as well as psychometric and autonomic cardiac assessment before and after completion of the biofeedback training using bivariate and multivariate regression analyses. Out of 48 patients who participated in the RCT, 27 patients (9 females, ages 42.9 ± 8.6, mean ± SD) completed our one-year follow-up. When including in the analysis only patients who completed follow-up, the rate of abstinence tended to be higher in patients who underwent HRV-biofeedback 1 year earlier compared to those who received rehabilitative treatment alone (66.7% vs 50%, p = ns). This non-significant trend was also observed in the intention-to-treat analysis where patients who did not participate in the follow-up were assumed to have relapsed (46,7% biofeedback vs. 33.3% controls, p = ns). Neither cardiac autonomic function nor psychometric variables were associated with abstinence 1 year after HRV-biofeedback. Our follow-up study provide a first indication of possible increase in long-term abstinence after HRV-biofeedback for alcohol dependence in addition to rehabilitation. The original randomized controlled trial was registered in the German Clinical Trials Register ( DRKS00004618 ). This one-year follow-up survey has not been

  8. Spallative nucleosynthesis in supernova remnants. II. Time-dependent numerical results

    Science.gov (United States)

    Parizot, Etienne; Drury, Luke

    1999-06-01

    We calculate the spallative production of light elements associated with the explosion of an isolated supernova in the interstellar medium, using a time-dependent model taking into account the dilution of the ejected enriched material and the adiabatic energy losses. We first derive the injection function of energetic particles (EPs) accelerated at both the forward and the reverse shock, as a function of time. Then we calculate the Be yields obtained in both cases and compare them to the value implied by the observational data for metal-poor stars in the halo of our Galaxy, using both O and Fe data. We find that none of the processes investigated here can account for the amount of Be found in these stars, which confirms the analytical results of Parizot & Drury (1999). We finally analyze the consequences of these results for Galactic chemical evolution, and suggest that a model involving superbubbles might alleviate the energetics problem in a quite natural way.

  9. Results on the energy dependence of cosmic-ray charge composition

    Science.gov (United States)

    Balasubrahmanyan, V. K.; Ormes, J. F.

    1973-01-01

    Results of measurements by a balloon-borne ionization spectrometer of the energy dependence of high-energy cosmic-ray charge composition. The results presented are greatly improved over those obtained earlier by Ormes et al. (1971) by the use of a multidimensional charge analysis with more efficient background rejection, and a more accurate energy determination. Complex couplings between the charge, energy, and trajectory information were taken into account and are discussed. The spectra of individual elements up to oxygen and of groups of nuclei up through iron were measured up to almost 100 GeV per nucleon. The energy spectrum of the secondary nuclei, B + N, is found to be steeper than that of the primary nuclei, C + O, in agreement with Smith et al. (1973). The most dramatic finding is that the spectrum of the iron nuclei is flatter than that of the carbon and oxygen nuclei by 0.57 plus or minus 0.14 of a power.

  10. Motivation and exercise dependence: a study based on self-determination theory.

    Science.gov (United States)

    González-Cutre, David; Sicilia, Alvaro

    2012-06-01

    The objective of this study was to use self-determination theory to analyze the relationships of several motivational variables with exercise dependence. The study involved 531 exercisers, ranging in age from 16 to 60 years old, who responded to differentquestionnaires assessing perception of motivational climate, satisfaction of basic psychological needs, motivation types, and exercise dependence. The results of multiple mediation analysis revealed that ego-involving climate and perceived competence positively predicted exercise dependence in a directed and mediated manner through introjected and external regulation. Gender and age did not moderate the analyzed relationships. These results allow us to better understand the motivational process explaining exercise dependence, demonstrating the negative influence of the ego-involving climate in the context of exercise.

  11. THE DIFFERENCES IN MORAL, GROUP IDENTITY AND THE PERCON’S VARIABILITY DEPENDING ON THE EDUCATION

    Directory of Open Access Journals (Sweden)

    Irina Aleksandrobna Kolinichenko

    2017-06-01

    Results. The results of the study have revealed the dominance of all specified assessment parameters in the group of test subjects with incomplete higher education: higher level of moral development in all dilemmas (the opposition of life values (compassion and following the law, self-interest – the interests of the city (law, business (benefit and law, personal interests (career and the freedom of another person, except for the dilemma of the opposition between the interests of a majority and a single person. The differences have also been revealed between the two groups of test subjects according to the group identity, group variability, the desirability of the common categories of identity.

  12. Partial summations of stationary sequences of non-Gaussian random variables

    DEFF Research Database (Denmark)

    Mohr, Gunnar; Ditlevsen, Ove Dalager

    1996-01-01

    The distribution of the sum of a finite number of identically distributed random variables is in many cases easily determined given that the variables are independent. The moments of any order of the sum can always be expressed by the moments of the single term without computational problems...... of convergence of the distribution of a sum (or an integral) of mutually dependent random variables to the Gaussian distribution. The paper is closely related to the work in Ditlevsen el al. [Ditlevsen, O., Mohr, G. & Hoffmeyer, P. Integration of non-Gaussian fields. Prob. Engng Mech 11 (1996) 15-23](2)....... lognormal variables or polynomials of standard Gaussian variables. The dependency structure is induced by specifying the autocorrelation structure of the sequence of standard Gaussian variables. Particularly useful polynomials are the Winterstein approximations that distributionally fit with non...

  13. A Pareto-Based Adaptive Variable Neighborhood Search for Biobjective Hybrid Flow Shop Scheduling Problem with Sequence-Dependent Setup Time

    Directory of Open Access Journals (Sweden)

    Huixin Tian

    2016-01-01

    Full Text Available Different from most researches focused on the single objective hybrid flowshop scheduling (HFS problem, this paper investigates a biobjective HFS problem with sequence dependent setup time. The two objectives are the minimization of total weighted tardiness and the total setup time. To efficiently solve this problem, a Pareto-based adaptive biobjective variable neighborhood search (PABOVNS is developed. In the proposed PABOVNS, a solution is denoted as a sequence of all jobs and a decoding procedure is presented to obtain the corresponding complete schedule. In addition, the proposed PABOVNS has three major features that can guarantee a good balance of exploration and exploitation. First, an adaptive selection strategy of neighborhoods is proposed to automatically select the most promising neighborhood instead of the sequential selection strategy of canonical VNS. Second, a two phase multiobjective local search based on neighborhood search and path relinking is designed for each selected neighborhood. Third, an external archive with diversity maintenance is adopted to store the nondominated solutions and at the same time provide initial solutions for the local search. Computational results based on randomly generated instances show that the PABOVNS is efficient and even superior to some other powerful multiobjective algorithms in the literature.

  14. Controllability Results For First Order Impulsive Stochastic Functional Differential Systems with State-Dependent Delay

    Directory of Open Access Journals (Sweden)

    C. Parthasarathy

    2013-03-01

    Full Text Available In this paper, we study the controllability results of first order impulsive stochastic differential and neutral differential systems with state-dependent delay by using semigroup theory. The controllability results are derived by the means of Leray-SchauderAlternative fixed point theorem. An example is provided to illustrate the theory.

  15. Dependence of conductivity on thickness within the variable-range hopping regime for Coulomb glasses

    Directory of Open Access Journals (Sweden)

    M. Caravaca

    Full Text Available In this paper, we provide some computational evidence concerning the dependence of conductivity on the system thickness for Coulomb glasses. We also verify the Efros–Shklovskii law and deal with the calculation of its characteristic parameter as a function of the thickness. Our results strengthen the link between theoretical and experimental fields. Keywords: Coulomb glass, Conductivity, Density of states, Efros–Shklovskii law

  16. Near-IR spectroscopic monitoring of CLASS I protostars: Variability of accretion and wind indicators

    Energy Technology Data Exchange (ETDEWEB)

    Connelley, Michael S. [Institute for Astronomy, University of Hawaii, 640 N. Aohoku Place, Hilo, HI 96720 (United States); Greene, Thomas P. [NASA Ames Research Center, M.S. 245-6, Moffett Field, CA 94035 (United States)

    2014-06-01

    We present the results of a program that monitored the near-IR spectroscopic variability of a sample of 19 embedded protostars. Spectra were taken on time intervals from 2 days to 3 yr, over a wavelength range from 0.85 μm to 2.45 μm, for 4-9 epochs of observations per target. We found that the spectra of all targets are variable and that every emission feature observed is also variable (although not for all targets). With one exception, there were no drastic changes in the continua of the spectra, nor did any line completely disappear, nor did any line appear that was not previously apparent. This analysis focuses on understanding the connection between accretion (traced by H Br γ and CO) and the wind (traced by He I, [Fe II], and sometimes H{sub 2}). For both accretion and wind tracers, the median variability was constant versus the time interval between observations; however, the maximum variability that we observed increased with the time interval between observations. Extinction is observed to vary within the minimum sampling time of 2 days, suggesting extinguishing material within a few stellar radii at high disk latitudes. The variability of [Fe II] and H{sub 2} were correlated for most (but not all) of the 7 young stellar objects showing both features, and the amplitude of the variability depends on the veiling. Although the occurrence of CO and Br γ emission are connected, their variability is uncorrelated, suggesting that these emissions originate in separate regions near the protostar (e.g., disk and wind). The variability of Br γ and wind tracers were found to be positively correlated, negatively correlated, or uncorrelated, depending on the target. The variability of Br γ, [Fe II], and H{sub 2} always lies on a plane, although the orientation of the plane in three dimensions depends on the target. While we do not understand all interactions behind the variability that we observed, we have shown that spectroscopic variability is a powerful tool

  17. Scale-dependent spatial variability in peatland lead pollution in the southern Pennines, UK.

    Science.gov (United States)

    Rothwell, James J; Evans, Martin G; Lindsay, John B; Allott, Timothy E H

    2007-01-01

    Increasingly, within-site and regional comparisons of peatland lead pollution have been undertaken using the inventory approach. The peatlands of the Peak District, southern Pennines, UK, have received significant atmospheric inputs of lead over the last few hundred years. A multi-core study at three peatland sites in the Peak District demonstrates significant within-site spatial variability in industrial lead pollution. Stochastic simulations reveal that 15 peat cores are required to calculate reliable lead inventories at the within-site and within-region scale for this highly polluted area of the southern Pennines. Within-site variability in lead pollution is dominant at the within-region scale. The study demonstrates that significant errors may be associated with peatland lead inventories at sites where only a single peat core has been used to calculate an inventory. Meaningful comparisons of lead inventories at the regional or global scale can only be made if the within-site variability of lead pollution has been quantified reliably.

  18. Probability densities and the radon variable transformation theorem

    International Nuclear Information System (INIS)

    Ramshaw, J.D.

    1985-01-01

    D. T. Gillespie recently derived a random variable transformation theorem relating to the joint probability densities of functionally dependent sets of random variables. The present author points out that the theorem can be derived as an immediate corollary of a simpler and more fundamental relation. In this relation the probability density is represented as a delta function averaged over an unspecified distribution of unspecified internal random variables. The random variable transformation is derived from this relation

  19. Variability Bugs:

    DEFF Research Database (Denmark)

    Melo, Jean

    . Although many researchers suggest that preprocessor-based variability amplifies maintenance problems, there is little to no hard evidence on how actually variability affects programs and programmers. Specifically, how does variability affect programmers during maintenance tasks (bug finding in particular......)? How much harder is it to debug a program as variability increases? How do developers debug programs with variability? In what ways does variability affect bugs? In this Ph.D. thesis, I set off to address such issues through different perspectives using empirical research (based on controlled...... experiments) in order to understand quantitatively and qualitatively the impact of variability on programmers at bug finding and on buggy programs. From the program (and bug) perspective, the results show that variability is ubiquitous. There appears to be no specific nature of variability bugs that could...

  20. Time-dependent Schroedinger equations with effective mass in (2 + 1) dimensions: intertwining relations and Darboux operators

    International Nuclear Information System (INIS)

    Cobian, Hector; Schulze-Halberg, Axel

    2011-01-01

    We construct Darboux transformations for time-dependent Schroedinger equations with position-dependent mass in (2 + 1) dimensions. Several examples illustrate our results, which complement and generalize former findings for the constant mass case in two spatial variables (Schulze-Halberg 2010 J. Math. Phys. 51 033521).

  1. Tail-weighted dependence measures with limit being the tail dependence coefficient

    KAUST Repository

    Lee, David

    2017-12-02

    For bivariate continuous data, measures of monotonic dependence are based on the rank transformations of the two variables. For bivariate extreme value copulas, there is a family of estimators (Formula presented.), for (Formula presented.), of the extremal coefficient, based on a transform of the absolute difference of the α power of the ranks. In the case of general bivariate copulas, we obtain the probability limit (Formula presented.) of (Formula presented.) as the sample size goes to infinity and show that (i) (Formula presented.) for (Formula presented.) is a measure of central dependence with properties similar to Kendall\\'s tau and Spearman\\'s rank correlation, (ii) (Formula presented.) is a tail-weighted dependence measure for large α, and (iii) the limit as (Formula presented.) is the upper tail dependence coefficient. We obtain asymptotic properties for the rank-based measure (Formula presented.) and estimate tail dependence coefficients through extrapolation on (Formula presented.). A data example illustrates the use of the new dependence measures for tail inference.

  2. Tail-weighted dependence measures with limit being the tail dependence coefficient

    KAUST Repository

    Lee, David; Joe, Harry; Krupskii, Pavel

    2017-01-01

    For bivariate continuous data, measures of monotonic dependence are based on the rank transformations of the two variables. For bivariate extreme value copulas, there is a family of estimators (Formula presented.), for (Formula presented.), of the extremal coefficient, based on a transform of the absolute difference of the α power of the ranks. In the case of general bivariate copulas, we obtain the probability limit (Formula presented.) of (Formula presented.) as the sample size goes to infinity and show that (i) (Formula presented.) for (Formula presented.) is a measure of central dependence with properties similar to Kendall's tau and Spearman's rank correlation, (ii) (Formula presented.) is a tail-weighted dependence measure for large α, and (iii) the limit as (Formula presented.) is the upper tail dependence coefficient. We obtain asymptotic properties for the rank-based measure (Formula presented.) and estimate tail dependence coefficients through extrapolation on (Formula presented.). A data example illustrates the use of the new dependence measures for tail inference.

  3. Oxygen-Dependent Cell-to-Cell Variability in the Output of the Escherichia coli Tor Phosphorelay.

    Science.gov (United States)

    Roggiani, Manuela; Goulian, Mark

    2015-06-15

    Escherichia coli senses and responds to trimethylamine-N-oxide (TMAO) in the environment through the TorT-TorS-TorR signal transduction system. The periplasmic protein TorT binds TMAO and stimulates the hybrid kinase TorS to phosphorylate the response regulator TorR through a phosphorelay. Phosphorylated TorR, in turn, activates transcription of the torCAD operon, which encodes the proteins required for anaerobic respiration via reduction of TMAO to trimethylamine. Interestingly, E. coli respires TMAO in both the presence and absence of oxygen, a behavior that is markedly different from the utilization of other alternative electron acceptors by this bacterium. Here we describe an unusual form of regulation by oxygen for this system. While the average level of torCAD transcription is the same for aerobic and anaerobic cultures containing TMAO, the behavior across the population of cells is strikingly different under the two growth conditions. Cellular levels of torCAD transcription in aerobic cultures are highly heterogeneous, in contrast to the relatively homogeneous distribution in anaerobic cultures. Thus, oxygen regulates the variance of the output but not the mean for the Tor system. We further show that this oxygen-dependent variability stems from the phosphorelay. Trimethylamine-N-oxide (TMAO) is utilized by numerous bacteria as an electron acceptor for anaerobic respiration. In E. coli, expression of the proteins required for TMAO respiration is tightly regulated by a signal transduction system that is activated by TMAO. Curiously, although oxygen is the energetically preferred electron acceptor, TMAO is respired even in the presence of oxygen. Here we describe an interesting and unexpected form of regulation for this system in which oxygen produces highly variable expression of the TMAO utilization proteins across a population of cells without affecting the mean expression of these proteins. To our knowledge, this is the first reported example of a stimulus

  4. Operator- and software-related post-experimental variability and source of error in 2-DE analysis.

    Science.gov (United States)

    Millioni, Renato; Puricelli, Lucia; Sbrignadello, Stefano; Iori, Elisabetta; Murphy, Ellen; Tessari, Paolo

    2012-05-01

    In the field of proteomics, several approaches have been developed for separating proteins and analyzing their differential relative abundance. One of the oldest, yet still widely used, is 2-DE. Despite the continuous advance of new methods, which are less demanding from a technical standpoint, 2-DE is still compelling and has a lot of potential for improvement. The overall variability which affects 2-DE includes biological, experimental, and post-experimental (software-related) variance. It is important to highlight how much of the total variability of this technique is due to post-experimental variability, which, so far, has been largely neglected. In this short review, we have focused on this topic and explained that post-experimental variability and source of error can be further divided into those which are software-dependent and those which are operator-dependent. We discuss these issues in detail, offering suggestions for reducing errors that may affect the quality of results, summarizing the advantages and drawbacks of each approach.

  5. Scale-dependent spatial variability in peatland lead pollution in the southern Pennines, UK

    International Nuclear Information System (INIS)

    Rothwell, James J.; Evans, Martin G.; Lindsay, John B.; Allott, Timothy E.H.

    2007-01-01

    Increasingly, within-site and regional comparisons of peatland lead pollution have been undertaken using the inventory approach. The peatlands of the Peak District, southern Pennines, UK, have received significant atmospheric inputs of lead over the last few hundred years. A multi-core study at three peatland sites in the Peak District demonstrates significant within-site spatial variability in industrial lead pollution. Stochastic simulations reveal that 15 peat cores are required to calculate reliable lead inventories at the within-site and within-region scale for this highly polluted area of the southern Pennines. Within-site variability in lead pollution is dominant at the within-region scale. The study demonstrates that significant errors may be associated with peatland lead inventories at sites where only a single peat core has been used to calculate an inventory. Meaningful comparisons of lead inventories at the regional or global scale can only be made if the within-site variability of lead pollution has been quantified reliably. - Multiple peat cores are required for accurate peatland Pb inventories

  6. Do Demographic Variables Moderate the Relationship Between Job Burnout and its Consequences?

    Directory of Open Access Journals (Sweden)

    Hasan Zarei Matin

    2012-01-01

    Full Text Available Many studies have already been conducted to understand the various dimensions of the burnout. The purpose of the present research is to investigate the moderating effect of demographic variables on the relationship between job burnout and its consequences among the staff of an Iranian public sector company. In this research, job burnout is considered as independent variable; organizational commitment, intention to leave and the employees‟ job satisfaction are dependent variables; and the age, gender, marital status and educational level are moderating variables. The results of this study show that firstly, the job burnout of employees in organizations leads to the decrease of organizational commitment and job satisfaction, and the increase of intention to leave; secondly, the demographic variables in this research don't affect on the relationship of job burnout with its consequences.

  7. Temperature-dependent behaviours are genetically variable in the nematode Caenorhabditis briggsae.

    Science.gov (United States)

    Stegeman, Gregory W; de Mesquita, Matthew Bueno; Ryu, William S; Cutter, Asher D

    2013-03-01

    Temperature-dependent behaviours in Caenorhabditis elegans, such as thermotaxis and isothermal tracking, are complex behavioural responses that integrate sensation, foraging and learning, and have driven investigations to discover many essential genetic and neural pathways. The ease of manipulation of the Caenorhabditis model system also has encouraged its application to comparative analyses of phenotypic evolution, particularly contrasts of the classic model C. elegans with C. briggsae. And yet few studies have investigated natural genetic variation in behaviour in any nematode. Here we measure thermotaxis and isothermal tracking behaviour in genetically distinct strains of C. briggsae, further motivated by the latitudinal differentiation in C. briggsae that is associated with temperature-dependent fitness differences in this species. We demonstrate that C. briggsae performs thermotaxis and isothermal tracking largely similar to that of C. elegans, with a tendency to prefer its rearing temperature. Comparisons of these behaviours among strains reveal substantial heritable natural variation within each species that corresponds to three general patterns of behavioural response. However, intraspecific genetic differences in thermal behaviour often exceed interspecific differences. These patterns of temperature-dependent behaviour motivate further development of C. briggsae as a model system for dissecting the genetic underpinnings of complex behavioural traits.

  8. Heart rate variability analysis in acute poisoning by cholinesterase inhibitors

    OpenAIRE

    JEONG, JINWOO; KIM, YONGIN

    2017-01-01

    Heart rate variability (HRV) has been associated with a variety of clinical situations. However, few studies have examined the association between HRV and acute poisoning. Organophosphate (OP) and carbamate inhibit esterase enzymes, particularly acetylcholinesterase, resulting in an accumulation of acetylcholine and thereby promoting excessive activation of corresponding receptors. Because diagnosis and treatment of OP and carbamate poisoning greatly depend on...

  9. A similarity solution of time dependent MHD liquid film flow over stretching sheet with variable physical properties

    Directory of Open Access Journals (Sweden)

    M. Idrees

    2018-03-01

    Full Text Available An analysis is performed for the fluid dynamics incorporating the variation of viscosity and thermal conductivity on an unsteady two-dimensional free surface flow of a viscous incompressible conducting fluid taking into account the effect of a magnetic field. Surface tension quadratically vary with temperature while fluid viscosity and thermal conductivity are assumed to vary as a linear function of temperature. The boundary layer partial differential equations in cartesian coordinates are transformed into a system of nonlinear ordinary differential equations (ODEs by similarity transformation. The developed nonlinear equations are solved analytically by Homotopy Analysis Method (HAM while numerically by using the shooting method. The Effects of natural parameters such as the variable viscosity parameter A, variable thermal conductivity parameter N, Hartmann number Ma, film Thickness, unsteadiness parameter S, Thermocapillary number M and Prandtl number Pr on the velocity and temperature profiles are investigated. The results for the surface skin friction coefficient f″(0, Nusselt number (heat flux -θ′(0 and free surface temperature θ(1 are presented graphically and in tabular form. Keywords: Variable viscosity and thermal conductivity, Thermocapillary number, Magnetic field, Thin film, Unsteady stretching surface

  10. Pacemaker Dependency after Cardiac Surgery: A Systematic Review of Current Evidence.

    Science.gov (United States)

    Steyers, Curtis M; Khera, Rohan; Bhave, Prashant

    2015-01-01

    Severe postoperative conduction disturbances requiring permanent pacemaker implantation frequently occur following cardiac surgery. Little is known about the long-term pacing requirements and risk factors for pacemaker dependency in this population. We performed a systematic review of the literature addressing rates and predictors of pacemaker dependency in patients requiring permanent pacemaker implantation after cardiac surgery. Using a comprehensive search of the Medline, Web of Science and EMBASE databases, studies were selected for review based on predetermined inclusion and exclusion criteria. A total of 8 studies addressing the endpoint of pacemaker-dependency were identified, while 3 studies were found that addressed the recovery of atrioventricular (AV) conduction endpoint. There were 10 unique studies with a total of 780 patients. Mean follow-up ranged from 6-72 months. Pacemaker dependency rates ranged from 32%-91% and recovery of AV conduction ranged from 16%-42%. There was significant heterogeneity with respect to the definition of pacemaker dependency. Several patient and procedure-specific variables were found to be independently associated with pacemaker dependency, but these were not consistent between studies. Pacemaker dependency following cardiac surgery occurs with variable frequency. While individual studies have identified various perioperative risk factors for pacemaker dependency and non-resolution of AV conduction disease, results have been inconsistent. Well-conducted studies using a uniform definition of pacemaker dependency might identify patients who will benefit most from early permanent pacemaker implantation after cardiac surgery.

  11. Modeling dependencies in product families with COVAMOF

    NARCIS (Netherlands)

    Sinnema, Marco; Deelstra, Sybren; Nijhuis, Jos; Bosch, Jan; Riebisch, M; Tabeling, P; Zorn, W

    2006-01-01

    Many variability modeling approaches consider only formalized dependencies, i.e. in- or exclude relations between variants. However, in real industrial product families, dependencies are often much more complicated. In this paper, we discuss the product derivation problems associated with

  12. Risk assessment of groundwater level variability using variable Kriging methods

    Science.gov (United States)

    Spanoudaki, Katerina; Kampanis, Nikolaos A.

    2015-04-01

    Assessment of the water table level spatial variability in aquifers provides useful information regarding optimal groundwater management. This information becomes more important in basins where the water table level has fallen significantly. The spatial variability of the water table level in this work is estimated based on hydraulic head measured during the wet period of the hydrological year 2007-2008, in a sparsely monitored basin in Crete, Greece, which is of high socioeconomic and agricultural interest. Three Kriging-based methodologies are elaborated in Matlab environment to estimate the spatial variability of the water table level in the basin. The first methodology is based on the Ordinary Kriging approach, the second involves auxiliary information from a Digital Elevation Model in terms of Residual Kriging and the third methodology calculates the probability of the groundwater level to fall below a predefined minimum value that could cause significant problems in groundwater resources availability, by means of Indicator Kriging. The Box-Cox methodology is applied to normalize both the data and the residuals for improved prediction results. In addition, various classical variogram models are applied to determine the spatial dependence of the measurements. The Matérn model proves to be the optimal, which in combination with Kriging methodologies provides the most accurate cross validation estimations. Groundwater level and probability maps are constructed to examine the spatial variability of the groundwater level in the basin and the associated risk that certain locations exhibit regarding a predefined minimum value that has been set for the sustainability of the basin's groundwater resources. Acknowledgement The work presented in this paper has been funded by the Greek State Scholarships Foundation (IKY), Fellowships of Excellence for Postdoctoral Studies (Siemens Program), 'A simulation-optimization model for assessing the best practices for the

  13. A moving mesh method with variable relaxation time

    OpenAIRE

    Soheili, Ali Reza; Stockie, John M.

    2006-01-01

    We propose a moving mesh adaptive approach for solving time-dependent partial differential equations. The motion of spatial grid points is governed by a moving mesh PDE (MMPDE) in which a mesh relaxation time \\tau is employed as a regularization parameter. Previously reported results on MMPDEs have invariably employed a constant value of the parameter \\tau. We extend this standard approach by incorporating a variable relaxation time that is calculated adaptively alongside the solution in orde...

  14. High-Rate Pacing Reduces Variability of Repolarization and Prevents Repolarization-Dependent Arrhythmias in Dogs With Chronic AV Block

    DEFF Research Database (Denmark)

    Oosterhoff, Peter; Thomsen, Morten Bækgaard; Maas, Joep N

    2010-01-01

    -term variability of repolarization (STV) as a feedback parameter of arrhythmic risk. Methods and Results: The minimal signal sampling frequency required for measuring STV was determined through computer simulation. Arrhythmogenic response to dofetilide (25 µg/kg/5minutes) was tested at two different paced heart...

  15. Upper and lower solutions for BVPs on the half-line with variable coefficient and derivative depending nonlinearity

    Directory of Open Access Journals (Sweden)

    S. Djebali

    2011-02-01

    Full Text Available This paper is concerned with a second-order nonlinear boundary value problem with a derivative depending nonlinearity and posed on the positive half-line. The derivative operator is time dependent. Upon a priori estimates and under a Nagumo growth condition, the Schauder's fixed point theorem combined with the method of upper and lower solutions on unbounded domains are used to prove existence of solutions. A uniqueness theorem is also obtained and some examples of application illustrate the obtained results.

  16. Intra-night Optical Variability Monitoring of Fermi Blazars: First Results from 1.3 m J. C. Bhattacharya Telescope

    Energy Technology Data Exchange (ETDEWEB)

    Paliya, Vaidehi S.; Ajello, M.; Kaur, A. [Department of Physics and Astronomy, Clemson University, Kinard Lab of Physics, Clemson, SC 29634-0978 (United States); Stalin, C. S., E-mail: vpaliya@g.clemson.edu [Indian Institute of Astrophysics, Block II, Koramangala, Bangalore-560034 (India)

    2017-07-20

    We report the first results obtained from our campaign to characterize the intra-night-optical variability (INOV) properties of Fermi detected blazars, using the observations from the recently commissioned 1.3 m J. C. Bhattacharya telescope (JCBT). During the first run, we were able to observe 17 blazars in the Bessel R filter for ∼137 hr. Using C- and scaled F -statistics, we quantify the extent of INOV and derive the duty cycle (DC), which is the fraction of time during which a source exhibits a substantial flux variability. We find a high DC of 40% for BL Lac objects and the flat spectrum radio quasars are relatively less variable (DC ∼ 15%). However, when estimated for blazars sub-classes, a high DC of ∼59% is found in low synchrotron peaked (LSP) blazars, whereas, intermediate and high synchrotron peaked objects have a low DC of ∼11% and 13%, respectively. We find evidence of the association of the high amplitude INOV with the γ -ray flaring state. We also notice a high polarization during the elevated INOV states (for the sources that have polarimetric data available), thus supporting the jet based origin of the observed variability. We plan to enlarge the sample and utilize the time availability from the small telescopes, such as 1.3 m JCBT, to strengthen/verify the results obtained in this work and those existing in the literature.

  17. A dependence modelling study of extreme rainfall in Madeira Island

    Science.gov (United States)

    Gouveia-Reis, Délia; Guerreiro Lopes, Luiz; Mendonça, Sandra

    2016-08-01

    The dependence between variables plays a central role in multivariate extremes. In this paper, spatial dependence of Madeira Island's rainfall data is addressed within an extreme value copula approach through an analysis of maximum annual data. The impact of altitude, slope orientation, distance between rain gauge stations and distance from the stations to the sea are investigated for two different periods of time. The results obtained highlight the influence of the island's complex topography on the spatial distribution of extreme rainfall in Madeira Island.

  18. Asymptotics of Multivariate Regression with Consecutively Added Dependent Varibles

    NARCIS (Netherlands)

    Raats, V.M.; van der Genugten, B.B.; Moors, J.J.A.

    2004-01-01

    We consider multivariate regression where new dependent variables are consecutively added during the experiment (or in time).So, viewed at the end of the experiment, the number of observations decreases with each added variable. The explanatory variables are observed throughout.In a previous paper

  19. Modelling comonotonic group-life under dependent decrement causes

    OpenAIRE

    Wang, Dabuxilatu

    2011-01-01

    Comonotonicity had been a extreme case of dependency between random variables. This article consider an extension of single life model under multiple dependent decrement causes to the case of comonotonic group-life.

  20. Intraspecies Variability Affects Heterotypic Biofilms of Porphyromonas gingivalis and Prevotella intermedia: Evidences of Strain-Dependence Biofilm Modulation by Physical Contact and by Released Soluble Factors.

    Directory of Open Access Journals (Sweden)

    Graziela Murta Barbosa

    Full Text Available It is well known that strain and virulence diversity exist within the population structure of Porphyromonas gingivalis. In the present study we investigate intra- and inter-species variability in biofilm formation of Porphyromonas gingivalis and partners Prevotella intermedia and Prevotella nigrescens. All strains tested showed similar hydrophobicity, except for P. gingivalis W83 which has roughly half of the hydrophobicity of P. gingivalis ATCC33277. An intraspecies variability in coaggregation of P. gingivalis with P. intermedia was also found. The association P. gingivalis W83/P. intermedia 17 produced the thickest biofilm and strain 17 was prevalent. In a two-compartment system P. gingivalis W83 stimulates an increase in biomass of strain 17 and the latter did not stimulate the growth of P. gingivalis W83. In addition, P. gingivalis W83 also stimulates the growth of P. intermedia ATCC25611 although strain W83 was prevalent in the association with P. intermedia ATCC25611. P. gingivalis ATCC33277 was prevalent in both associations with P. intermedia and both strains of P. intermedia stimulate the growth of P. gingivalis ATCC33277. FISH images also showed variability in biofilm structure. Thus, the outcome of the association P. gingivalis/P. intermedia seems to be strain-dependent, and both soluble factors and physical contact are relevant. The association P. gingivalis-P. nigrescens ATCC33563 produced larger biomass than each monotypic biofilm, and P. gingivalis was favored in consortia, while no differences were found in the two-compartment system. Therefore, in consortia P. gingivalis-P. nigrescens physical contact seems to favor P. gingivalis growth. The intraspecies variability found in our study suggests strain-dependence in ability of microorganisms to recognize molecules in other bacteria which may further elucidate the dysbiosis event during periodontitis development giving additional explanation for periodontal bacteria, such as P

  1. Intraspecies Variability Affects Heterotypic Biofilms of Porphyromonas gingivalis and Prevotella intermedia: Evidences of Strain-Dependence Biofilm Modulation by Physical Contact and by Released Soluble Factors.

    Science.gov (United States)

    Barbosa, Graziela Murta; Colombo, Andrea Vieira; Rodrigues, Paulo Henrique; Simionato, Maria Regina Lorenzetti

    2015-01-01

    It is well known that strain and virulence diversity exist within the population structure of Porphyromonas gingivalis. In the present study we investigate intra- and inter-species variability in biofilm formation of Porphyromonas gingivalis and partners Prevotella intermedia and Prevotella nigrescens. All strains tested showed similar hydrophobicity, except for P. gingivalis W83 which has roughly half of the hydrophobicity of P. gingivalis ATCC33277. An intraspecies variability in coaggregation of P. gingivalis with P. intermedia was also found. The association P. gingivalis W83/P. intermedia 17 produced the thickest biofilm and strain 17 was prevalent. In a two-compartment system P. gingivalis W83 stimulates an increase in biomass of strain 17 and the latter did not stimulate the growth of P. gingivalis W83. In addition, P. gingivalis W83 also stimulates the growth of P. intermedia ATCC25611 although strain W83 was prevalent in the association with P. intermedia ATCC25611. P. gingivalis ATCC33277 was prevalent in both associations with P. intermedia and both strains of P. intermedia stimulate the growth of P. gingivalis ATCC33277. FISH images also showed variability in biofilm structure. Thus, the outcome of the association P. gingivalis/P. intermedia seems to be strain-dependent, and both soluble factors and physical contact are relevant. The association P. gingivalis-P. nigrescens ATCC33563 produced larger biomass than each monotypic biofilm, and P. gingivalis was favored in consortia, while no differences were found in the two-compartment system. Therefore, in consortia P. gingivalis-P. nigrescens physical contact seems to favor P. gingivalis growth. The intraspecies variability found in our study suggests strain-dependence in ability of microorganisms to recognize molecules in other bacteria which may further elucidate the dysbiosis event during periodontitis development giving additional explanation for periodontal bacteria, such as P. gingivalis and P

  2. Preliminary results of variable star search using KMTNet data

    Directory of Open Access Journals (Sweden)

    Jeon Young-Beom

    2017-01-01

    Full Text Available The KMTNet (Korea Microlensing Telescope Network was completed on October 2nd in 2015. There are three 1.6 m telescopes in Chile (CTIO, Australia (SSO and South Africa (SAAO. The field of view of the CCD camera is 2 degree × 2 degree. We are monitoring and observing the bulge region for 24-hour continuous observations using the KMTNet telescopes. I present the characteristics of CCD camera and telescope, and the status of observation programs. We are still developing CCD cameras to accurate photometry. From the KMTNet data, we can obtain accurate 24-hour continuous time-series data for many variable stars.

  3. X-Ray Variability Characteristics of the Seyfert 1 Galaxy NGC 3783

    Science.gov (United States)

    Markowitz, A.

    2005-12-01

    We have characterized the energy-dependent X-ray variability properties of the Seyfert 1 galaxy NGC 3783 using archival XMM-Newton and Rossi X-Ray Timing Explorer data. The high-frequency fluctuation power spectral density function (PSD) slope is consistent with flattening toward higher energies. Light-curve cross-correlation functions yield no significant lags, but peak coefficients generally decrease as energy separation of the bands increases on both short and long timescales. We have measured the coherence between various X-ray bands over the temporal frequency range of 6×10-8-1×10-4 Hz; this range includes the temporal frequency of the low-frequency PSD break tentatively detected by Markowitz et al. and includes the lowest temporal frequency over which coherence has been measured in any active galactic nucleus to date. Coherence is generally near unity at these temporal frequencies, although it decreases slightly as energy separation of the bands increases. Temporal frequency-dependent phase lags are detected on short timescales; phase lags are consistent with increasing as energy separation increases or as temporal frequency decreases. All of these results are similar to those obtained previously for several Seyfert galaxies and stellar mass black hole systems. Qualitatively, these results are consistent with the variability models of Kotov et al. and Lyubarskii, wherein the X-ray variability is due to inwardly propagating variations in the local mass accretion rate.

  4. Exactly solvable position dependent mass schroedinger equation

    International Nuclear Information System (INIS)

    Koc, R.; Tuetuencueler, H.; Koercuek, E.

    2002-01-01

    Exact solution of the Schrodinger equation with a variable mass is presented. We have derived general expressions for the eigenstates and eigenvalues of the position dependent mass systems. We provide supersymmetric and Lie algebraic methods to discuss the position dependent mass systems

  5. A fundamental study of a variable critical nozzle flow

    International Nuclear Information System (INIS)

    Kim, Jea Hyung; Kim, Heuy Dong; Park, Kyung Am

    2003-01-01

    The mass flow rate of gas flow through critical nozzle depends on the nozzle supply conditions and the cross-sectional area at the nozzle throat. In order that the critical nozzle can be operated at a wide range of supply conditions, the nozzle throat diameter should be controlled to change the flow passage area. This can be achieved by means of a variable critical nozzle. In the present study, both experimental and computational works are performed to develop variable critical nozzle. A cone-cylinder with a diameter of d is inserted into conventional critical nozzle. It can move both upstream and downstream, thereby changing the cross-sectional area of the nozzle throat. Computational work using the axisymmetric, compressible Navier-Stokes equations is carried out to simulate the variable critical nozzle flow. An experiment is performed to measure the mass flow rate through variable critical nozzle. The present computational results are in close agreement with measured ones. The boundary layer displacement and momentum thickness are given as a function of Reynolds number. An empirical equation is obtained to predict the discharge coefficient of variable critical nozzle

  6. Small scale denitrification variability in riparian zones: Results from a high-resolution dataset

    Science.gov (United States)

    Gassen, Niklas; Knöller, Kay; Musolff, Andreas; Popp, Felix; Lüders, Tillmann; Stumpp, Christine

    2017-04-01

    Riparian zones are important compartments at the interface between groundwater and surface water where biogeochemical processes like denitrification are often enhanced. Nitrate loads of either groundwater entering a stream through the riparian zone or streamwater infiltrating into the riparian zone can be substantially reduced. These processes are spatially and temporally highly variable, making it difficult to capture solute variabilities, estimate realistic turnover rates and thus to quantify integral mass removal. A crucial step towards a more detailed characterization is to monitor solutes on a scale which adequately resemble the highly heterogeneous distribution and on a scale where processes occur. We measured biogeochemical parameters in a spatial high resolution within a riparian corridor of a German lowland river system over the course of one year. Samples were taken from three newly developed high-resolution multi-level wells with a maximum vertical resolution of 5 cm and analyzed for major ions, DOC and N-O isotopes. Sediment derived during installation of the wells was analyzed for specific denitrifying enzymes. Results showed a distinct depth zonation of hydrochemistry within the shallow alluvial aquifer, with a 1 m thick zone just below the water table with lower nitrate concentrations and EC values similar to the nearby river. Conservative parameters were consistent inbetween the three wells, but nitrate was highly variable. In addition, spots with low nitrate concentrations showed isotopic and microbial evidence for higher denitrification activities. The depth zonation was observed throughout the year, with stronger temporal variations of nitrate concentrations just below the water table compared to deeper layers. Nitrate isotopes showed a clear seasonal trend of denitrification activities (high in summer, low in winter). Our dataset gives new insight into river-groundwater exchange processes and shows the highly heterogeneous distribution of

  7. Time-Dependent Behavior of High-Strength Kevlar and Vectran Webbing

    Science.gov (United States)

    Jones, Thomas C.; Doggett, William R.

    2014-01-01

    High-strength Kevlar and Vectran webbings are currently being used by both NASA and industry as the primary load-bearing structure in inflatable space habitation modules. The time-dependent behavior of high-strength webbing architectures is a vital area of research that is providing critical material data to guide a more robust design process for this class of structures. This paper details the results of a series of time-dependent tests on 1-inch wide webbing including an initial set of comparative tests between specimens that underwent realtime and accelerated creep at 65 and 70% of their ultimate tensile strength. Variability in the ultimate tensile strength of the webbings is investigated and compared with variability in the creep life response. Additional testing studied the effects of load and displacement rate, specimen length and the time-dependent effects of preconditioning the webbings. The creep test facilities, instrumentation and test procedures are also detailed. The accelerated creep tests display consistently longer times to failure than their real-time counterparts; however, several factors were identified that may contribute to the observed disparity. Test setup and instrumentation, grip type, loading scheme, thermal environment and accelerated test postprocessing along with material variability are among these factors. Their effects are discussed and future work is detailed for the exploration and elimination of some of these factors in order to achieve a higher fidelity comparison.

  8. Dealing with Dependent Uncertainty in Modelling: A Comparative Study Case through the Airy Equation

    Directory of Open Access Journals (Sweden)

    J.-C. Cortés

    2013-01-01

    Full Text Available The consideration of uncertainty in differential equations leads to the emergent area of random differential equations. Under this approach, inputs become random variables and/or stochastic processes. Often one assumes that inputs are independent, a hypothesis that simplifies the mathematical treatment although it could not be met in applications. In this paper, we analyse, through the Airy equation, the influence of statistical dependence of inputs on the output, computing its expectation and standard deviation by Fröbenius and Polynomial Chaos methods. The results are compared with Monte Carlo sampling. The analysis is conducted by the Airy equation since, as in the deterministic scenario its solutions are highly oscillatory, it is expected that differences will be better highlighted. To illustrate our study, and motivated by the ubiquity of Gaussian random variables in numerous practical problems, we assume that inputs follow a multivariate Gaussian distribution throughout the paper. The application of Fröbenius method to solve Airy equation is based on an extension of the method to the case where inputs are dependent. The numerical results show that the existence of statistical dependence among the inputs and its magnitude entails changes on the variability of the output.

  9. A search for β Cephei variable stars in the Magellanic Clouds: motivation and first results for the LMC

    International Nuclear Information System (INIS)

    Sterken, C.; Jerzykiewicz, M.

    1988-01-01

    Motivation for starting a programme of detecting and investigating β Cephei variables in the Magellanic Clouds is given. Differential photoelectric observations are then reported of six LMC stars which fall in the instability strip defined by the galactic β Cephei variables. Three programme stars are found to exhibit short-term brightness variations. One of them, showing a sinusoidal light-curve with an amplitude (half-range) equal to 0.0070 ± 0.0011 mag and a period equal to about 5 hr, is a promising β Cephei candidate. In the case of the other two variable programme stars, the interpretation of the results is less straightforward. The remaining three programme stars are shown to be constant on a short time-scale, two to within ± 0.010 mag, and one to within ± 0.005 magn. (author)

  10. The Impact of The Quality of Financial Statements on Local Revenue Using Examination Opinion Results as Moderating Variable

    Directory of Open Access Journals (Sweden)

    Arik - Susbiyani

    2017-02-01

    Full Text Available Abstract   This study aimed to examine the influence of the financial statements on local revenue by using the results of the examination opinion as moderating variable. The study used Legitimacy Theory to explain and analyze the relationship between variables. The population in the study was all the districts and cities in Indonesia totaling 497 county and city governments. The sampling method used in the study was judgment sampling. Samples that met the criteria of the study were 116 local governments. The analytical tool used in this research was the analysis of MRA (Moderated Regression Analysis. The results showed that the effects of the partial test of the quality of financial reports to local revenues were not significant positive effects. While the partial test results stating the influence of audit opinion on local revenue having positive effects were not significant. Other results showed that the interaction between the results of the examination opinion to the quality of financial statements was  insignificant on the quality of financial statements. In other words, the results of the examination opinions moderated (strengthened the relationship between quality of financial report on local revenue of district and city governments in Indonesia.

  11. Statistical validity of using ratio variables in human kinetics research.

    Science.gov (United States)

    Liu, Yuanlong; Schutz, Robert W

    2003-09-01

    The purposes of this study were to investigate the validity of the simple ratio and three alternative deflation models and examine how the variation of the numerator and denominator variables affects the reliability of a ratio variable. A simple ratio and three alternative deflation models were fitted to four empirical data sets, and common criteria were applied to determine the best model for deflation. Intraclass correlation was used to examine the component effect on the reliability of a ratio variable. The results indicate that the validity, of a deflation model depends on the statistical characteristics of the particular component variables used, and an optimal deflation model for all ratio variables may not exist. Therefore, it is recommended that different models be fitted to each empirical data set to determine the best deflation model. It was found that the reliability of a simple ratio is affected by the coefficients of variation and the within- and between-trial correlations between the numerator and denominator variables. It was recommended that researchers should compute the reliability of the derived ratio scores and not assume that strong reliabilities in the numerator and denominator measures automatically lead to high reliability in the ratio measures.

  12. The relationship between venture capital investment and macro economic variables via statistical computation method

    Science.gov (United States)

    Aygunes, Gunes

    2017-07-01

    The objective of this paper is to survey and determine the macroeconomic factors affecting the level of venture capital (VC) investments in a country. The literary depends on venture capitalists' quality and countries' venture capital investments. The aim of this paper is to give relationship between venture capital investment and macro economic variables via statistical computation method. We investigate the countries and macro economic variables. By using statistical computation method, we derive correlation between venture capital investments and macro economic variables. According to method of logistic regression model (logit regression or logit model), macro economic variables are correlated with each other in three group. Venture capitalists regard correlations as a indicator. Finally, we give correlation matrix of our results.

  13. State-dependent neutral delay equations from population dynamics.

    Science.gov (United States)

    Barbarossa, M V; Hadeler, K P; Kuttler, C

    2014-10-01

    A novel class of state-dependent delay equations is derived from the balance laws of age-structured population dynamics, assuming that birth rates and death rates, as functions of age, are piece-wise constant and that the length of the juvenile phase depends on the total adult population size. The resulting class of equations includes also neutral delay equations. All these equations are very different from the standard delay equations with state-dependent delay since the balance laws require non-linear correction factors. These equations can be written as systems for two variables consisting of an ordinary differential equation (ODE) and a generalized shift, a form suitable for numerical calculations. It is shown that the neutral equation (and the corresponding ODE--shift system) is a limiting case of a system of two standard delay equations.

  14. Predator persistence through variability of resource productivity in Tritrophic systems

    DEFF Research Database (Denmark)

    Soudijn, Floor Helena; de Roos, Andre M.

    2017-01-01

    The trophic structure of species communities depends on the energy transfer between trophic levels. Primary productivity varies strongly through time, challenging the persistence of species at higher trophic levels. Yet resource variability has mostly been studied in systems with only one or two...... trophic levels. We test the effect of variability in resource productivity in a tritrophic model system including a resource, a size-structured consumer, and a size-specific predator. The model complies with fundamental principles of mass conservation and the body-size dependence of individual......-level energetics and predator-prey interactions. Surprisingly, we find that resource variability may promote predator persistence. The positive effect of variability on the predator arises through periods with starvation mortality of juvenile prey, which reduces the intraspecific competition in the prey population...

  15. BROAD ABSORPTION LINE VARIABILITY ON MULTI-YEAR TIMESCALES IN A LARGE QUASAR SAMPLE

    Energy Technology Data Exchange (ETDEWEB)

    Filiz Ak, N.; Brandt, W. N.; Schneider, D. P. [Department of Astronomy and Astrophysics, Pennsylvania State University, University Park, PA 16802 (United States); Hall, P. B. [Department of Physics and Astronomy, York University, 4700 Keele St., Toronto, Ontario, M3J 1P3 (Canada); Anderson, S. F. [Astronomy Department, University of Washington, Seattle, WA 98195 (United States); Hamann, F. [Department of Astronomy, University of Florida, Gainesville, FL 32611-2055 (United States); Lundgren, B. F. [Department of Astronomy, University of Wisconsin, Madison, WI 53706 (United States); Myers, Adam D. [Department of Physics and Astronomy, University of Wyoming, Laramie, WY 82071 (United States); Pâris, I. [Departamento de Astronomía, Universidad de Chile, Casilla 36-D, Santiago (Chile); Petitjean, P. [Universite Paris 6, Institut d' Astrophysique de Paris, 75014, Paris (France); Ross, Nicholas P. [Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 92420 (United States); Shen, Yue [Harvard-Smithsonian Center for Astrophysics, 60 Garden St., MS-51, Cambridge, MA 02138 (United States); York, Don, E-mail: nfilizak@astro.psu.edu [The University of Chicago, Department of Astronomy and Astrophysics, Chicago, IL 60637 (United States)

    2013-11-10

    We present a detailed investigation of the variability of 428 C IV and 235 Si IV broad absorption line (BAL) troughs identified in multi-epoch observations of 291 quasars by the Sloan Digital Sky Survey-I/II/III. These observations primarily sample rest-frame timescales of 1-3.7 yr over which significant rearrangement of the BAL wind is expected. We derive a number of observational results on, e.g., the frequency of BAL variability, the velocity range over which BAL variability occurs, the primary observed form of BAL-trough variability, the dependence of BAL variability upon timescale, the frequency of BAL strengthening versus weakening, correlations between BAL variability and BAL-trough profiles, relations between C IV and Si IV BAL variability, coordinated multi-trough variability, and BAL variations as a function of quasar properties. We assess implications of these observational results for quasar winds. Our results support models where most BAL absorption is formed within an order-of-magnitude of the wind-launching radius, although a significant minority of BAL troughs may arise on larger scales. We estimate an average lifetime for a BAL trough along our line-of-sight of a few thousand years. BAL disappearance and emergence events appear to be extremes of general BAL variability, rather than being qualitatively distinct phenomena. We derive the parameters of a random-walk model for BAL EW variability, finding that this model can acceptably describe some key aspects of EW variability. The coordinated trough variability of BAL quasars with multiple troughs suggests that changes in 'shielding gas' may play a significant role in driving general BAL variability.

  16. How variable is the number of triggered aftershocks?

    Science.gov (United States)

    Marsan, D.; Helmstetter, A.

    2017-07-01

    Aftershock activity depends at first order on the main shock magnitude but also shows important fluctuations between shocks of equal magnitude. We here investigate these fluctuations, by quantifying them and by relating them to the main shock stress drop and other variables, for southern California earthquakes. A method is proposed in order to only count directly triggered aftershocks, rather than secondary aftershocks (i.e., triggered by previous aftershocks), and to only quantify fluctuations going beyond the natural Poisson variability. Testing of the method subjected to various model errors allows to quantify its robustness. It is found that these fluctuations follow a distribution that is well fitted by a lognormal distribution, with a coefficient of variation of about 1.0 to 1.1. A simple model is proposed to relate this observed dependence to main shock stress drop variability.

  17. Degree of multicollinearity and variables involved in linear dependence in additive-dominant models Grau de multicolinearidade e variáveis envolvidas na dependência linear em modelos aditivo-dominantes

    Directory of Open Access Journals (Sweden)

    Juliana Petrini

    2012-12-01

    Full Text Available The objective of this work was to assess the degree of multicollinearity and to identify the variables involved in linear dependence relations in additive-dominant models. Data of birth weight (n=141,567, yearling weight (n=58,124, and scrotal circumference (n=20,371 of Montana Tropical composite cattle were used. Diagnosis of multicollinearity was based on the variance inflation factor (VIF and on the evaluation of the condition indexes and eigenvalues from the correlation matrix among explanatory variables. The first model studied (RM included the fixed effect of dam age class at calving and the covariates associated to the direct and maternal additive and non-additive effects. The second model (R included all the effects of the RM model except the maternal additive effects. Multicollinearity was detected in both models for all traits considered, with VIF values of 1.03 - 70.20 for RM and 1.03 - 60.70 for R. Collinearity increased with the increase of variables in the model and the decrease in the number of observations, and it was classified as weak, with condition index values between 10.00 and 26.77. In general, the variables associated with additive and non-additive effects were involved in multicollinearity, partially due to the natural connection between these covariables as fractions of the biological types in breed composition.O objetivo deste trabalho foi avaliar o grau de multicolinearidade e identificar as variáveis envolvidas na dependência linear em modelos aditivo-dominantes. Foram utilizados dados de peso ao nascimento (n=141.567, peso ao ano (n=58.124 e perímetro escrotal (n=20.371 de bovinos de corte compostos Montana Tropical. O diagnóstico de multicolinearidade foi baseado no fator de inflação de variância (VIF e no exame dos índices de condição e dos autovalores da matriz de correlações entre as variáveis explanatórias. O primeiro modelo estudado (RM incluiu o efeito fixo de classe de idade da mãe ao parto e

  18. Evidence for a time-invariant phase variable in human ankle control.

    Directory of Open Access Journals (Sweden)

    Robert D Gregg

    Full Text Available Human locomotion is a rhythmic task in which patterns of muscle activity are modulated by state-dependent feedback to accommodate perturbations. Two popular theories have been proposed for the underlying embodiment of phase in the human pattern generator: a time-dependent internal representation or a time-invariant feedback representation (i.e., reflex mechanisms. In either case the neuromuscular system must update or represent the phase of locomotor patterns based on the system state, which can include measurements of hundreds of variables. However, a much simpler representation of phase has emerged in recent designs for legged robots, which control joint patterns as functions of a single monotonic mechanical variable, termed a phase variable. We propose that human joint patterns may similarly depend on a physical phase variable, specifically the heel-to-toe movement of the Center of Pressure under the foot. We found that when the ankle is unexpectedly rotated to a position it would have encountered later in the step, the Center of Pressure also shifts forward to the corresponding later position, and the remaining portion of the gait pattern ensues. This phase shift suggests that the progression of the stance ankle is controlled by a biomechanical phase variable, motivating future investigations of phase variables in human locomotor control.

  19. RNA-seq: technical variability and sampling

    Science.gov (United States)

    2011-01-01

    Background RNA-seq is revolutionizing the way we study transcriptomes. mRNA can be surveyed without prior knowledge of gene transcripts. Alternative splicing of transcript isoforms and the identification of previously unknown exons are being reported. Initial reports of differences in exon usage, and splicing between samples as well as quantitative differences among samples are beginning to surface. Biological variation has been reported to be larger than technical variation. In addition, technical variation has been reported to be in line with expectations due to random sampling. However, strategies for dealing with technical variation will differ depending on the magnitude. The size of technical variance, and the role of sampling are examined in this manuscript. Results In this study three independent Solexa/Illumina experiments containing technical replicates are analyzed. When coverage is low, large disagreements between technical replicates are apparent. Exon detection between technical replicates is highly variable when the coverage is less than 5 reads per nucleotide and estimates of gene expression are more likely to disagree when coverage is low. Although large disagreements in the estimates of expression are observed at all levels of coverage. Conclusions Technical variability is too high to ignore. Technical variability results in inconsistent detection of exons at low levels of coverage. Further, the estimate of the relative abundance of a transcript can substantially disagree, even when coverage levels are high. This may be due to the low sampling fraction and if so, it will persist as an issue needing to be addressed in experimental design even as the next wave of technology produces larger numbers of reads. We provide practical recommendations for dealing with the technical variability, without dramatic cost increases. PMID:21645359

  20. Identification of phreatophytic groundwater dependent ecosystems using geospatial technologies

    Science.gov (United States)

    Perez Hoyos, Isabel Cristina

    The protection of groundwater dependent ecosystems (GDEs) is increasingly being recognized as an essential aspect for the sustainable management and allocation of water resources. Ecosystem services are crucial for human well-being and for a variety of flora and fauna. However, the conservation of GDEs is only possible if knowledge about their location and extent is available. Several studies have focused on the identification of GDEs at specific locations using ground-based measurements. However, recent progress in technologies such as remote sensing and their integration with geographic information systems (GIS) has provided alternative ways to map GDEs at much larger spatial extents. This study is concerned with the discovery of patterns in geospatial data sets using data mining techniques for mapping phreatophytic GDEs in the United States at 1 km spatial resolution. A methodology to identify the probability of an ecosystem to be groundwater dependent is developed. Probabilities are obtained by modeling the relationship between the known locations of GDEs and main factors influencing groundwater dependency, namely water table depth (WTD) and aridity index (AI). A methodology is proposed to predict WTD at 1 km spatial resolution using relevant geospatial data sets calibrated with WTD observations. An ensemble learning algorithm called random forest (RF) is used in order to model the distribution of groundwater in three study areas: Nevada, California, and Washington, as well as in the entire United States. RF regression performance is compared with a single regression tree (RT). The comparison is based on contrasting training error, true prediction error, and variable importance estimates of both methods. Additionally, remote sensing variables are omitted from the process of fitting the RF model to the data to evaluate the deterioration in the model performance when these variables are not used as an input. Research results suggest that although the prediction

  1. Brain Signal Variability Differentially Affects Cognitive Flexibility and Cognitive Stability.

    Science.gov (United States)

    Armbruster-Genç, Diana J N; Ueltzhöffer, Kai; Fiebach, Christian J

    2016-04-06

    Recent research yielded the intriguing conclusion that, in healthy adults, higher levels of variability in neuronal processes are beneficial for cognitive functioning. Beneficial effects of variability in neuronal processing can also be inferred from neurocomputational theories of working memory, albeit this holds only for tasks requiring cognitive flexibility. However, cognitive stability, i.e., the ability to maintain a task goal in the face of irrelevant distractors, should suffer under high levels of brain signal variability. To directly test this prediction, we studied both behavioral and brain signal variability during cognitive flexibility (i.e., task switching) and cognitive stability (i.e., distractor inhibition) in a sample of healthy human subjects and developed an efficient and easy-to-implement analysis approach to assess BOLD-signal variability in event-related fMRI task paradigms. Results show a general positive effect of neural variability on task performance as assessed by accuracy measures. However, higher levels of BOLD-signal variability in the left inferior frontal junction area result in reduced error rate costs during task switching and thus facilitate cognitive flexibility. In contrast, variability in the same area has a detrimental effect on cognitive stability, as shown in a negative effect of variability on response time costs during distractor inhibition. This pattern was mirrored at the behavioral level, with higher behavioral variability predicting better task switching but worse distractor inhibition performance. Our data extend previous results on brain signal variability by showing a differential effect of brain signal variability that depends on task context, in line with predictions from computational theories. Recent neuroscientific research showed that the human brain signal is intrinsically variable and suggested that this variability improves performance. Computational models of prefrontal neural networks predict differential

  2. A space and time scale-dependent nonlinear geostatistical approach for downscaling daily precipitation and temperature

    KAUST Repository

    Jha, Sanjeev Kumar

    2015-07-21

    A geostatistical framework is proposed to downscale daily precipitation and temperature. The methodology is based on multiple-point geostatistics (MPS), where a multivariate training image is used to represent the spatial relationship between daily precipitation and daily temperature over several years. Here, the training image consists of daily rainfall and temperature outputs from the Weather Research and Forecasting (WRF) model at 50 km and 10 km resolution for a twenty year period ranging from 1985 to 2004. The data are used to predict downscaled climate variables for the year 2005. The result, for each downscaled pixel, is daily time series of precipitation and temperature that are spatially dependent. Comparison of predicted precipitation and temperature against a reference dataset indicates that both the seasonal average climate response together with the temporal variability are well reproduced. The explicit inclusion of time dependence is explored by considering the climate properties of the previous day as an additional variable. Comparison of simulations with and without inclusion of time dependence shows that the temporal dependence only slightly improves the daily prediction because the temporal variability is already well represented in the conditioning data. Overall, the study shows that the multiple-point geostatistics approach is an efficient tool to be used for statistical downscaling to obtain local scale estimates of precipitation and temperature from General Circulation Models. This article is protected by copyright. All rights reserved.

  3. Variables Associated With Tic Exacerbation in Children With Chronic Tic Disorders.

    Science.gov (United States)

    Himle, Michael B; Capriotti, Matthew R; Hayes, Loran P; Ramanujam, Krishnapriya; Scahill, Lawrence; Sukhodolsky, Denis G; Wilhelm, Sabine; Deckersbach, Thilo; Peterson, Alan L; Specht, Matt W; Walkup, John T; Chang, Susanna; Piacentini, John

    2014-03-01

    Research has shown that motor and vocal tics fluctuate in frequency, intensity, and form in response to environmental and contextual cues. Behavioral models have proposed that some of the variation in tics may reflect context-dependent interactive learning processes such that once tics are performed, they are influenced by environmental contingencies. The current study describes the results of a function-based assessment of tics (FBAT) from a recently completed study comparing Comprehensive Behavioral Intervention for Tics (CBIT) with supportive psychotherapy. The current study describes the frequency with which antecedent and consequence variables were reported to exacerbate tics and the relationships between these functional variables and sample baseline characteristics, comorbidities, and measures of tic severity. Results showed that tic-exacerbating antecedents and consequences were nearly ubiquitous in a sample of children with chronic tic disorder. In addition, functional variables were related to baseline measures of comorbid internalizing symptoms and specific measures of tic severity. © The Author(s) 2014.

  4. Smooth time-dependent receiver operating characteristic curve estimators.

    Science.gov (United States)

    Martínez-Camblor, Pablo; Pardo-Fernández, Juan Carlos

    2018-03-01

    The receiver operating characteristic curve is a popular graphical method often used to study the diagnostic capacity of continuous (bio)markers. When the considered outcome is a time-dependent variable, two main extensions have been proposed: the cumulative/dynamic receiver operating characteristic curve and the incident/dynamic receiver operating characteristic curve. In both cases, the main problem for developing appropriate estimators is the estimation of the joint distribution of the variables time-to-event and marker. As usual, different approximations lead to different estimators. In this article, the authors explore the use of a bivariate kernel density estimator which accounts for censored observations in the sample and produces smooth estimators of the time-dependent receiver operating characteristic curves. The performance of the resulting cumulative/dynamic and incident/dynamic receiver operating characteristic curves is studied by means of Monte Carlo simulations. Additionally, the influence of the choice of the required smoothing parameters is explored. Finally, two real-applications are considered. An R package is also provided as a complement to this article.

  5. Time-dependent reliability analysis of flood defences

    International Nuclear Information System (INIS)

    Buijs, F.A.; Hall, J.W.; Sayers, P.B.; Gelder, P.H.A.J.M. van

    2009-01-01

    This paper describes the underlying theory and a practical process for establishing time-dependent reliability models for components in a realistic and complex flood defence system. Though time-dependent reliability models have been applied frequently in, for example, the offshore, structural safety and nuclear industry, application in the safety-critical field of flood defence has to date been limited. The modelling methodology involves identifying relevant variables and processes, characterisation of those processes in appropriate mathematical terms, numerical implementation, parameter estimation and prediction. A combination of stochastic, hierarchical and parametric processes is employed. The approach is demonstrated for selected deterioration mechanisms in the context of a flood defence system. The paper demonstrates that this structured methodology enables the definition of credible statistical models for time-dependence of flood defences in data scarce situations. In the application of those models one of the main findings is that the time variability in the deterioration process tends to be governed the time-dependence of one or a small number of critical attributes. It is demonstrated how the need for further data collection depends upon the relevance of the time-dependence in the performance of the flood defence system.

  6. Determining Directional Dependency in Causal Associations

    Science.gov (United States)

    Pornprasertmanit, Sunthud; Little, Todd D.

    2012-01-01

    Directional dependency is a method to determine the likely causal direction of effect between two variables. This article aims to critique and improve upon the use of directional dependency as a technique to infer causal associations. We comment on several issues raised by von Eye and DeShon (2012), including: encouraging the use of the signs of…

  7. Variable importance and prediction methods for longitudinal problems with missing variables.

    Directory of Open Access Journals (Sweden)

    Iván Díaz

    Full Text Available We present prediction and variable importance (VIM methods for longitudinal data sets containing continuous and binary exposures subject to missingness. We demonstrate the use of these methods for prognosis of medical outcomes of severe trauma patients, a field in which current medical practice involves rules of thumb and scoring methods that only use a few variables and ignore the dynamic and high-dimensional nature of trauma recovery. Well-principled prediction and VIM methods can provide a tool to make care decisions informed by the high-dimensional patient's physiological and clinical history. Our VIM parameters are analogous to slope coefficients in adjusted regressions, but are not dependent on a specific statistical model, nor require a certain functional form of the prediction regression to be estimated. In addition, they can be causally interpreted under causal and statistical assumptions as the expected outcome under time-specific clinical interventions, related to changes in the mean of the outcome if each individual experiences a specified change in the variable (keeping other variables in the model fixed. Better yet, the targeted MLE used is doubly robust and locally efficient. Because the proposed VIM does not constrain the prediction model fit, we use a very flexible ensemble learner (the SuperLearner, which returns a linear combination of a list of user-given algorithms. Not only is such a prediction algorithm intuitive appealing, it has theoretical justification as being asymptotically equivalent to the oracle selector. The results of the analysis show effects whose size and significance would have been not been found using a parametric approach (such as stepwise regression or LASSO. In addition, the procedure is even more compelling as the predictor on which it is based showed significant improvements in cross-validated fit, for instance area under the curve (AUC for a receiver-operator curve (ROC. Thus, given that 1 our VIM

  8. The effects of patient and physician characteristics on early outpatient satisfaction with substance dependence care: results of the SUBUSQOL study

    Directory of Open Access Journals (Sweden)

    Bourion-Bédès S

    2017-05-01

    Full Text Available Stéphanie Bourion-Bédès,1–3 Raymund Schwan,2 Paolo Di Patrizio,2 Guillaume Vlamynck,2 Sarah Viennet,2 Maxime Schvartz,2 Anne Gaunard,2 Alex Bédès,4 Isabelle Clerc-Urmès,5 Cédric Baumann3,5 1Regional Medical and Psychological Service (SMPR, 2CSAPA (Healthcare Center of Accompaniment and Prevention in Addictology, University Hospital of Nancy, 3EA4360 APEMAC, University of Lorraine, Nancy, 4ANPAA 15-CSAPA (Healthcare Center of Accompaniment and Prevention in Addictology, Saint-Flour, Cantal, 5Platform of Clinical Research Facility PARC, Unit MDS, University Hospital of Nancy, Nancy, France Background: Although patient perceptions of health care have increasingly been explored in the literature, little is known about care satisfaction among individuals with substance dependence. This exploratory study assessed the relationships between patient and physician characteristics and early outpatient satisfaction with care for alcohol and opioid dependence. Methods: Satisfaction was assessed using a multidimensional, self-administered and validated questionnaire during the early care process among a prospective outpatient cohort. In addition to measuring satisfaction and obtaining sociodemographic and clinical data, this study collected data on the self-reported health status and physician characteristics at inclusion. Cross-sectional analysis with multiple linear regression was performed to identify the variables associated with satisfaction level. Results: A total of 249 outpatients were included, and 63.8% completed the satisfaction questionnaire. Patients without a history of previous care for substance dependence were more satisfied with the appointment-making process (β=7.2; P=0.029 and with the doctor consultation (β=10.3; P=0.003 than those who had received care previously. Neither sociodemographic characteristics nor self-reported health status was associated with outpatient satisfaction. Conclusion: The factors that affect patients

  9. Population activity statistics dissect subthreshold and spiking variability in V1.

    Science.gov (United States)

    Bányai, Mihály; Koman, Zsombor; Orbán, Gergő

    2017-07-01

    Response variability, as measured by fluctuating responses upon repeated performance of trials, is a major component of neural responses, and its characterization is key to interpret high dimensional population recordings. Response variability and covariability display predictable changes upon changes in stimulus and cognitive or behavioral state, providing an opportunity to test the predictive power of models of neural variability. Still, there is little agreement on which model to use as a building block for population-level analyses, and models of variability are often treated as a subject of choice. We investigate two competing models, the doubly stochastic Poisson (DSP) model assuming stochasticity at spike generation, and the rectified Gaussian (RG) model tracing variability back to membrane potential variance, to analyze stimulus-dependent modulation of both single-neuron and pairwise response statistics. Using a pair of model neurons, we demonstrate that the two models predict similar single-cell statistics. However, DSP and RG models have contradicting predictions on the joint statistics of spiking responses. To test the models against data, we build a population model to simulate stimulus change-related modulations in pairwise response statistics. We use single-unit data from the primary visual cortex (V1) of monkeys to show that while model predictions for variance are qualitatively similar to experimental data, only the RG model's predictions are compatible with joint statistics. These results suggest that models using Poisson-like variability might fail to capture important properties of response statistics. We argue that membrane potential-level modeling of stochasticity provides an efficient strategy to model correlations. NEW & NOTEWORTHY Neural variability and covariability are puzzling aspects of cortical computations. For efficient decoding and prediction, models of information encoding in neural populations hinge on an appropriate model of

  10. On the explaining-away phenomenon in multivariate latent variable models.

    Science.gov (United States)

    van Rijn, Peter; Rijmen, Frank

    2015-02-01

    Many probabilistic models for psychological and educational measurements contain latent variables. Well-known examples are factor analysis, item response theory, and latent class model families. We discuss what is referred to as the 'explaining-away' phenomenon in the context of such latent variable models. This phenomenon can occur when multiple latent variables are related to the same observed variable, and can elicit seemingly counterintuitive conditional dependencies between latent variables given observed variables. We illustrate the implications of explaining away for a number of well-known latent variable models by using both theoretical and real data examples. © 2014 The British Psychological Society.

  11. On history dependence of stress-strain diagrams and creep curves under variable repeated loading

    International Nuclear Information System (INIS)

    Gokhfeld, D.A.; Sadakov, O.S.; Martynenko, M.E.

    1979-01-01

    The ability of structural alloys to 'keep in memory' the loading prehistory becomes of special importance when inelastic variable repeated loading is considered. There are two main approaches to the development of the mathematical description of this phenomenon: the inclusion of hidden state variables in the incremental theory constitutive equations (a) and construction of proper hereditary functionals (b). In this respect the assumption that the 'memory' regarding the previous deformation history is due to structural nonhomogeneity of actual materials proves to be fruitful. (orig.)

  12. Variability in response to albuminuria-lowering drugs

    DEFF Research Database (Denmark)

    Petrykiv, Sergei I; de Zeeuw, Dick; Persson, Frederik

    2017-01-01

    AIMS: Albuminuria-lowering drugs have shown different effect size in different individuals. Since urine albumin levels are known to vary considerably from day-to-day, we questioned whether the between-individual variability in albuminuria response after therapy initiation reflects a random...... variability or a true response variation to treatment. In addition, we questioned whether the response variability is drug dependent. METHODS: To determine whether the response to treatment is random or a true drug response, we correlated in six clinical trials the change in albuminuria during placebo...... or active treatment (on-treatment) with the change in albuminuria during wash-out (off-treatment). If these responses correlate during active treatment, it suggests that at least part of the response variability can be attributed to drug response variability. We tested this for enalapril, losartan...

  13. Recent results on neutrino, antineutrino charged current interactions at NAL

    International Nuclear Information System (INIS)

    Aubert, B.; Benvenuti, A.; Cline, D.; Ford, W.T.; Imlay, R.; Ling, T.Y.; Mann, A.K.; Messing, F.; Piccioni, R.L.; Pilcher, J.; Reeder, D.D.; Rubbia, C.; Stefanski, R.; Sulak, L.

    The dependence of the neutrino cross section on energy has been measured to 160GeV. The ratio sigma(antineutrino)/sigma(neutrino) is measured up to 70GeV. Preliminary results are presented for the distributions of the scaling variables x, y observed in neutrino induced events

  14. A review of age dependent radioiodine dosimetry

    International Nuclear Information System (INIS)

    Johnson, J.R.

    1987-01-01

    Age dependent models of radioiodine metabolism in humans have been described. These models have been used to calculate age dependent committed doses to the thyroid from intakes of radioiodines. A model of fetal iodine metabolism is also described and used to calculate fetal thyroid doses from intakes of radioiodines by the mother. These doses are calculated using model parameter values thought to be representative of average for North American/European populations. Considerable variability from these results can be expected for individuals. In addition, population with significant differences in stable iodine intake, and in body parameters, will have model parameters somewhat different than the ones described in this paper. These different model parameters will result in different doses from intakes of radioiodines, but it is doubtful if the differences in population would be as large as the variation between individuals. 25 refs.; 11 figs.; 1 table

  15. Conductance of partially disordered graphene: crossover from temperature-dependent to field-dependent variable-range hopping

    International Nuclear Information System (INIS)

    Cheah, C Y; Jaurigue, L C; Kaiser, A B; Gómez-Navarro, C

    2013-01-01

    We report an analysis of low-temperature measurements of the conductance of partially disordered reduced graphene oxide, finding that the data follow a simple crossover scenario. At room temperature, the conductance is dominated by two-dimensional (2D) electric field-assisted, thermally driven (Pollak–Riess) variable-range hopping (VRH) through highly disordered regions. However, at lower temperatures T, we find a smooth crossover to follow the exp(−E 0 /E) 1/3 field-driven (Shklovskii) 2D VRH conductance behaviour when the electric field E exceeds a specific crossover value E C (T) 2D =(E a E 0 1/3 /3) 3/4 determined by the scale factors E 0 and E a for the high-field and intermediate-field regimes respectively. Our crossover scenario also accounts well for experimental data reported by other authors for three-dimensional disordered carbon networks, suggesting wide applicability. (paper)

  16. Delayed Ego Strength Development in Opioid Dependent Adolescents and Young Adults

    Science.gov (United States)

    Abramoff, Benjamin A.; Lange, Hannah L. H.; Matson, Steven C.; Cottrill, Casey B.; Bridge, Jeffrey A.; Abdel-Rasoul, Mahmoud; Bonny, Andrea E.

    2015-01-01

    Objective. To evaluate ego strengths, in the context of Erikson's framework, among adolescents and young adults diagnosed with opioid dependence as compared to non-drug using youth. Methods. Opioid dependent (n = 51) and non-drug using control (n = 31) youth completed the self-administered Psychosocial Inventory of Ego Strengths (PIES). The PIES assesses development in the framework of Erikson's ego strength stages. Multivariate linear regression modeling assessed the independent association of the primary covariate (opioid dependent versus control) as well as potential confounding variables (e.g., psychiatric comorbidities, intelligence) with total PIES score. Results. Mean total PIES score was significantly lower in opioid dependent youth (231.65 ± 30.39 opioid dependent versus 270.67 ± 30.06 control; p development. A treatment approach acknowledging this delay may be needed in the counseling and treatment of adolescents with opioid dependence. PMID:26664819

  17. On solving wave equations on fixed bounded intervals involving Robin boundary conditions with time-dependent coefficients

    Science.gov (United States)

    van Horssen, Wim T.; Wang, Yandong; Cao, Guohua

    2018-06-01

    In this paper, it is shown how characteristic coordinates, or equivalently how the well-known formula of d'Alembert, can be used to solve initial-boundary value problems for wave equations on fixed, bounded intervals involving Robin type of boundary conditions with time-dependent coefficients. A Robin boundary condition is a condition that specifies a linear combination of the dependent variable and its first order space-derivative on a boundary of the interval. Analytical methods, such as the method of separation of variables (SOV) or the Laplace transform method, are not applicable to those types of problems. The obtained analytical results by applying the proposed method, are in complete agreement with those obtained by using the numerical, finite difference method. For problems with time-independent coefficients in the Robin boundary condition(s), the results of the proposed method also completely agree with those as for instance obtained by the method of separation of variables, or by the finite difference method.

  18. Scalable conditional induction variables (CIV) analysis

    KAUST Repository

    Oancea, Cosmin E.

    2015-02-01

    Subscripts using induction variables that cannot be expressed as a formula in terms of the enclosing-loop indices appear in the low-level implementation of common programming abstractions such as Alter, or stack operations and pose significant challenges to automatic parallelization. Because the complexity of such induction variables is often due to their conditional evaluation across the iteration space of loops we name them Conditional Induction Variables (CIV). This paper presents a flow-sensitive technique that summarizes both such CIV-based and affine subscripts to program level, using the same representation. Our technique requires no modifications of our dependence tests, which is agnostic to the original shape of the subscripts, and is more powerful than previously reported dependence tests that rely on the pairwise disambiguation of read-write references. We have implemented the CIV analysis in our parallelizing compiler and evaluated its impact on five Fortran benchmarks. We have found that that there are many important loops using CIV subscripts and that our analysis can lead to their scalable parallelization. This in turn has led to the parallelization of the benchmark programs they appear in.

  19. Genetic variability and heritability studies of some reproductive traits ...

    African Journals Online (AJOL)

    GRACE

    2006-07-03

    Jul 3, 2006 ... The success of most crop improvement programs largely depends upon the genetic variability and the heritability of desirable traits. The magnitude and type of genetic variability help the breeder to determine the selection criteria and breeding schemes to be used for improvement purposes. A screen.

  20. The roles of time and displacement in velocity-dependent volumetric strain of fault zones

    Science.gov (United States)

    Beeler, N.M.; Tullis, T.E.

    1997-01-01

    The relationship between measured friction??A and volumetric strain during frictional sliding was determined using a rate and state variable dependent friction constitutive equation, a common work balance relating friction and volume change, and two types of experimental faults: initially bare surfaces of Westerly granite and rock surfaces separated by a 1 mm layer of derivative of fault normal displacement with respect shear displacement, d??n ld??s. An implication of this relationship is that the rate dependence of d??n ld??s contributes to the rate dependence of ??A. Experiments show changes in sliding velocity lead to changes in both fault strength and volume. Analysis of data with the rate and state equations combined with the work balance relationship preclude the conventional interpretation of the direct effect in the rate and state variable constitutive equations. Consideration of a model bare surface fault consisting of an undeformable indentor sliding on a deformable surface reveals a serious flaw in the work balance relationship if volume change is time-dependent. For the model, at zero slip rate indentation creep under the normal load leads to time-dependent strengthening of the fault surface but, according to the work balance relationship, no work is done because compaction or dilatancy can only be induced by shearing. Additional tests on initially bare surfaces and gouges show that fault normal strain in experiments is time-dependent, consistent with the model. This time-dependent fault normal strain, which is not accounted for in the work balance relationship, explains the inconsistency between the constitutive equations and the work balance. For initially bare surface faults, all rate dependence of volume change is due to time dependence. Similar results are found for gouge. We conclude that ??A reflects the frictional resistance that results in shear heating, and no correction needs to be made for the volume changes. The result that time-dependent

  1. Modeling of carbon sequestration in coal-beds: A variable saturated simulation

    International Nuclear Information System (INIS)

    Liu Guoxiang; Smirnov, Andrei V.

    2008-01-01

    Storage of carbon dioxide in deep coal seams is a profitable method to reduce the concentration of green house gases in the atmosphere while the methane as a byproduct can be extracted during carbon dioxide injection into the coal seam. In this procedure, the key element is to keep carbon dioxide in the coal seam without escaping for a long term. It is depended on many factors such as properties of coal basin, fracture state, phase equilibrium, etc., especially the porosity, permeability and saturation of the coal seam. In this paper, a variable saturation model was developed to predict the capacity of carbon dioxide sequestration and coal-bed methane recovery. This variable saturation model can be used to track the saturation variability with the partial pressures change caused by carbon dioxide injection. Saturation variability is a key factor to predict the capacity of carbon dioxide storage and methane recovery. Based on this variable saturation model, a set of related variables including capillary pressure, relative permeability, porosity, coupled adsorption model, concentration and temperature equations were solved. From results of the simulation, historical data agree with the variable saturation model as well as the adsorption model constructed by Langmuir equations. The Appalachian basin, as an example, modeled the carbon dioxide sequestration in this paper. The results of the study and the developed models can provide the projections for the CO 2 sequestration and methane recovery in coal-beds within different regional specifics

  2. Mycorrhizal dependency of laurel (Ocotea sp.)

    International Nuclear Information System (INIS)

    Sierra-Escobar, Jorge A; Castro Restrepo, Dagoberto; Osorio Vega, Walter

    2009-01-01

    A greenhouse experiment was carried out to determine the mycorrhizal dependency of laurel (>Ocotea sp.). In order to do this, a completely randomized experimental design was used, with six treatments in a factorial array of 3 x 2 and five repetitions. The treatments involved a combination of three Phosphorus (P) levels in soil solution (0.002, 0.02 and 0.2 mg L-1) and two levels of mycorrhizal inoculation, either inoculated or non-inoculated with Glomus aggregatum Schenck and Smith. The leaf P content as a function of time was used as an output variable. Shoot dry matter, shoot P content, mycorrhizal colonization of roots, and mycorrhizal dependence were measured at harvest. The results indicated that the leaf P content increased significantly when using the mycorrhizal inoculation in laurel at P level 0.2 mg L -1, but not in the other P levels, on some of the sampling days. Shoot dry weight and total plant P content did not increase at all levels of soil available P. Mycorrhizal dependency of laurel reached 28%, which allows this species to be classified as moderately dependent on mycorrhiza.

  3. The Effect of Cooperative Learning Model and Kolb Learning Styles on Learning Result of the Basics of Politics

    Science.gov (United States)

    Sugiharto

    2015-01-01

    The aims of this research were to determine the effect of cooperative learning model and learning styles on learning result. This quasi-experimental study employed a 2x2 treatment by level, involved independent variables, i.e. cooperative learning model and learning styles, and learning result as the dependent variable. Findings signify that: (1)…

  4. SU-F-T-113: Inherent Functional Dependence of Spinal Cord Doses of Variable Irradiated Volumes in Spine SBRT

    Energy Technology Data Exchange (ETDEWEB)

    Ma, L; Braunstein, S; Chiu, J [University of California San Francisco, San Francisco, CA (United States); Sahgal, A [Sunnybrook Health Sciences Center, University of Toronto, Toronto, Ontario (Canada)

    2016-06-15

    Purpose: Spinal cord tolerance for SBRT has been recommended for the maximum point dose level or at irradiated volumes such as 0.35 mL or 10% of contoured volumes. In this study, we investigated an inherent functional relationship that associates these dose surrogates for irradiated spinal cord volumes of up to 3.0 mL. Methods: A hidden variable termed as Effective Dose Radius (EDR) was formulated based on a dose fall-off model to correlate dose at irradiated spinal cord volumes ranging from 0 mL (point maximum) to 3.0 mL. A cohort of 15 spine SBRT cases was randomly selected to derive an EDR-parameterized formula. The mean prescription dose for the studied cases was 21.0±8.0 Gy (range, 10–40Gy) delivered in 3±1 fractions with target volumes of 39.1 ± 70.6 mL. Linear regression and variance analysis were performed for the fitting parameters of variable EDR values. Results: No direct correlation was found between the dose at maximum point and doses at variable spinal cord volumes. For example, Pearson R{sup 2} = 0.643 and R{sup 2}= 0.491 were obtained when correlating the point maximum dose with the spinal cord dose at 1 mL and 3 mL, respectively. However, near perfect correlation (R{sup 2} ≥0.99) was obtained when corresponding parameterized EDRs. Specifically, Pearson R{sup 2}= 0.996 and R{sup 2} = 0.990 were obtained when correlating EDR (maximum point dose) with EDR (dose at 1 mL) and EDR(dose at 3 mL), respectively. As a result, high confidence level look-up tables were established to correlate spinal cord doses at the maximum point to any finite irradiated volumes. Conclusion: An inherent functional relationship was demonstrated for spine SBRT. Such a relationship unifies dose surrogates at variable cord volumes and proves that a single dose surrogate (e.g. point maximum dose) is mathematically sufficient in constraining the overall spinal cord dose tolerance for SBRT.

  5. Predictors of patient dependence in mild-to-moderate Alzheimer's disease.

    Science.gov (United States)

    Benke, Thomas; Sanin, Günter; Lechner, Anita; Dal-Bianco, Peter; Ransmayr, Gerhard; Uranüs, Margarete; Marksteiner, Josef; Gaudig, Maren; Schmidt, Reinhold

    2015-01-01

    Patient dependence has rarely been studied in mild-to-moderate Alzheimer's disease (AD). To identify factors which predict patient dependence in mild-to-moderate AD. We studied 398 non-institutionalized AD patients (234 females) of the ongoing Prospective Registry on Dementia (PRODEM) in Austria. The Dependence Scale (DS) was used to assess patient dependence. Patient assessment comprised functional abilities, neuropsychiatric symptoms and cognitive functions. A multiple linear regression analysis was performed to identify predictors of patient dependence. AD patients were mildly-to-moderately impaired (mean scores and SDs were: CDR 0.84 ± 0.43; DAD 74.4 ± 23.3, MMSE = 22.5 ± 3.6). Psychopathology and caregiver burden were in the low range (mean NPI score 13.2, range 0 to 98; mean ZBI score 18, range 0-64). Seventy five percent of patients were classified as having a mild level of patient dependence (DS sum score 0 to 6). Patient dependence correlated significantly and positively with age, functional measures, psychopathology and depression, disease duration, and caregiver burden. Significant negative, but low correlations were found between patient dependence, cognitive variables, and global cognition. Activities of daily living, patient age, and disease severity accounted for 63% of variance in patient dependence, whereas cognitive variables accounted for only 11%. Dependence in this cohort was mainly related to age and functional impairment, and less so to cognitive and neuropsychiatric variables. This differs from studies investigating patients in more advanced disease stages which found abnormal behavior and impairments of cognition as main predictors of patient dependence.

  6. Common characterization of variability and forecast errors of variable energy sources and their mitigation using reserves in power system integration studies

    Energy Technology Data Exchange (ETDEWEB)

    Menemenlis, N.; Huneault, M. [IREQ, Varennes, QC (Canada); Robitaille, A. [Dir. Plantif. de la Production Eolienne, Montreal, QC (Canada). HQ Production; Holttinen, H. [VTT Technical Research Centre of Finland, VTT (Finland)

    2012-07-01

    This In this paper we define and characterize the two random variables, variability and forecast error, over which uncertainty in power systems operations is characterized and mitigated. We show that the characterization of both these variables can be carried out with the same mathematical tools. Furthermore, this common characterization of random variables lends itself to a common methodology for the calculation of non-contingency reserves required to mitigate their effects. A parallel comparison of these two variables demonstrates similar inherent statistical properties. They depend on imminent conditions, evolve with time and can be asymmetric. Correlation is an important factor when aggregating individual wind farm characteristics in forming the distribution of the total wind generation for imminent conditions. (orig.)

  7. Groundwater level responses to precipitation variability in Mediterranean insular aquifers

    Science.gov (United States)

    Lorenzo-Lacruz, Jorge; Garcia, Celso; Morán-Tejeda, Enrique

    2017-09-01

    Groundwater is one of the largest and most important sources of fresh water on many regions under Mediterranean climate conditions, which are exposed to large precipitation variability that includes frequent meteorological drought episodes, and present high evapotranspiration rates and water demand during the dry season. The dependence on groundwater increases in those areas with predominant permeable lithologies, contributing to aquifer recharge and the abundance of ephemeral streams. The increasing pressure of tourism on water resources in many Mediterranean coastal areas, and uncertainty related to future precipitation and water availability, make it urgent to understand the spatio-temporal response of groundwater bodies to precipitation variability, if sustainable use of the resource is to be achieved. We present an assessment of the response of aquifers to precipitation variability based on correlations between the Standardized Precipitation Index (SPI) at various time scales and the Standardized Groundwater Index (SGI) across a Mediterranean island. We detected three main responses of aquifers to accumulated precipitation anomalies: (i) at short time scales of the SPI (24 months). The differing responses were mainly explained by differences in lithology and the percentage of highly permeable rock strata in the aquifer recharge areas. We also identified differences in the months and seasons when aquifer storages are more dependent on precipitation; these were related to climate seasonality and the degree of aquifer exploitation or underground water extraction. The recharge of some aquifers, especially in mountainous areas, is related to precipitation variability within a limited spatial extent, whereas for aquifers located in the plains, precipitation variability influence much larger areas; the topography and geological structure of the island explain these differences. Results indicate large spatial variability in the response of aquifers to precipitation in

  8. [Drug abuse in adolescent offenders: analysis of the psychosocial variables involved].

    Science.gov (United States)

    Contreras Martínez, Lourdes; Molina Banqueri, Virginia; Cano Lozano, Ma Carmen

    2012-01-01

    Research shows that drugs and delinquency are frequently linked, the abuse of various types of substance being a widespread practice among young offenders. At the same time, some psychosocial characteristics are associated with both drug abuse and criminal/antisocial behavior. To help us explore the relationship between young offenders' drug abuse and certain psychosocial variables, we examined closed judicial files on young offenders from the Juvenile Justice Service in Jaen (Spain) corresponding to the period 2001 to 2010. From the contents of these judicial files we analyzed demographic variables such as gender and age, as well as psychosocial variables such as drug abuse, peer group, violent behavior, self-control, tolerance to frustration and attributional style. The results show that most of the young offenders use some type of drug, as well as revealing differential patterns of use according to gender. Also observed is a link between drug abuse and deviant peer group, violent behavior and the above-mentioned psychological variables. Finally, we found some differences in these psychological variables depending on the type of drug used.

  9. Variability of Pinus halepensis Mill. Essential Oils and Their Antioxidant Activities Depending on the Stage of Growth During Vegetative Cycle.

    Science.gov (United States)

    Djerrad, Zineb; Djouahri, Abderrahmane; Kadik, Leila

    2017-04-01

    The impact of growth stages during vegetative cycle (B 0  - B 5 ) on chemical composition and antioxidant activities of Pinus halepensis Mill. needles essential oils was investigated for the first time. GC and GC/MS analyses pointed to a quantitative variability of components; terpene hydrocarbons derivatives, represented by α-pinene (8.5 - 12.9%), myrcene (17.5 - 21.6%), p-cymene (7.9 - 11.9%) and (Z)-β-caryophyllene (17.3 - 21.2%) as major components, decreased from 88.9% at B 0 growth stage to 66.9% at B 5 growth stage, whereas oxygenated derivatives, represented by caryophyllene oxide (5.4 - 12.6%) and terpinen-4-ol (0.4 - 3.3%) as major components, increased from 7% at B 0 growth stage to 28.4% at B 5 growth stage. Furthermore, our findings showed that essential oil of P. halepensis needles collected at B 5 growth stage possess higher antioxidant activities by four different testing systems than those collected at B 0  - B 4 growth stages. This highlighted variability led to conclude that we should select essential oils to be investigated carefully depending on growth stage, in order to have the highest effectiveness of essential oil in terms of biological activities for human health purposes. © 2017 Wiley-VHCA AG, Zurich, Switzerland.

  10. [Variable magnetic fields in the treatment of tics disorders - preliminary results].

    Science.gov (United States)

    Pasek, Jarosław; Jędrzejewska, Anna; Jagodziński, Leszek; Obuchowicz, Anna; Flak, Maria; Sieroń, Aleksander

    Tics disorders is frequent pathological syndrome, particularly typical for children's age. The symptoms of this disease are differential, and their intensification individualized, which makes difficult unique recognition. Tics disorders concern the most often the muscles of face, head, upper limbs and trunk. The study group consisted of 16 patients (11 boys and 5 girls) with tics complex disorders about unknown etiology particularly relating of face and upper limbs muscles. In the treatment were the interventions with use a magnetotherapy and magnetostimulation applied. The procedures were ones daily by 3 weeks in two series executed. It author's pool was the frequency of occurrence tics disorders as well as the proportional opinion of effectiveness conducted treatment estimated. After 10 weeks in 14 patients was the decrease of occurrence frequency involuntary movements observed, in proportional scale about 75%. The results of subjective opinion of mood showed, that decrease the frequency tics disorders had in all children the direct shift on improvement their mood, and also satisfaction in their parents. The use of variable magnetic fields influenced on decrease the occurrence frequency tics disorders, and also on improvement quality of life the treated patients.

  11. Additive measures of travel time variability

    DEFF Research Database (Denmark)

    Engelson, Leonid; Fosgerau, Mogens

    2011-01-01

    This paper derives a measure of travel time variability for travellers equipped with scheduling preferences defined in terms of time-varying utility rates, and who choose departure time optimally. The corresponding value of travel time variability is a constant that depends only on preference...... parameters. The measure is unique in being additive with respect to independent parts of a trip. It has the variance of travel time as a special case. Extension is provided to the case of travellers who use a scheduled service with fixed headway....

  12. Time-Dependent Drug Administration in Hypertension and its Effect on Blood Pressure Variability

    OpenAIRE

    Magdás Annamária; Podoleanu Cristian; Tusa Anna-Boróka; Găburoi Adina; Incze Alexandru

    2017-01-01

    Background: Optimizing blood pressure variability seems to represent a new therapeutic target in the management of hypertension. It is emphasized that scheduling at least one antihypertensive agent at bedtime, has the ability to reduce blood pressure.

  13. Sensitivity of Numerical Weather Prediction to the Choice of Variable for Atmospheric Moisture Analysis into the Brazilian Global Model Data Assimilation System

    Directory of Open Access Journals (Sweden)

    Thamiris B. Campos

    2018-03-01

    Full Text Available Due to the high spatial and temporal variability of atmospheric water vapor associated with the deficient methodologies used in its quantification and the imperfect physics parameterizations incorporated in the models, there are significant uncertainties in characterizing the moisture field. The process responsible for incorporating the information provided by observation into the numerical weather prediction is denominated data assimilation. The best result in atmospheric moisture depend on the correct choice of the moisture control variable. Normalized relative humidity and pseudo-relative humidity are the variables usually used by the main weather prediction centers. The objective of this study is to assess the sensibility of the Center for Weather Forecast and Climate Studies to choose moisture control variable in the data assimilation scheme. Experiments using these variables are carried out. The results show that the pseudo-relative humidity improves the variables that depend on temperature values but damage the moisture field. The opposite results show when the simulation used the normalized relative humidity. These experiments suggest that the pseudo-relative humidity should be used in the cyclical process of data assimilation and the normalized relative humidity should be used in non-cyclic process (e.g., nowcasting application in high resolution.

  14. Affective Dependence and Aggression: An Exploratory Study

    Directory of Open Access Journals (Sweden)

    Filippo Petruccelli

    2014-01-01

    Full Text Available Introduction. Emotionally dependent subjects may engage in controlling, restrictive, and aggressive behaviours, which limit their partner’s autonomy. The underlying causes of such behaviours are not solely based on levels of aggression, but act as a mean of maintaining the subject’s own sense of self-worth, identity, and general functioning. Objective. The aim of the paper is to explore the correlation between affective dependency and reactive/proactive aggression and to evaluate individual differences as predisposing factors for aggressive behaviour and emotional dependency. Methods. The Spouse-Specific Dependency Scale (SSDS and the Reactive Proactive Questionnaire (RPQ were administered to a sample of 3375 subjects. Results. In the whole sample, a positive correlation between emotional dependency and proactive aggression was identified. Differences with regard to sex, age group, and geographical distribution were evidenced for the scores of the different scales. Conclusion. A fundamental distinction between reactive and proactive aggression was observed, anchoring proactive aggression more strictly to emotional dependency. Sociocultural and demographical variables, together with the previous structuring of attachment styles, help to determine the scope, frequency, and intensity of the demands made to the partner, as well as to feed the fears of loss, abandonment, or betrayal.

  15. Effect of land use on the spatial variability of organic matter and nutrient status in an Oxisol

    Science.gov (United States)

    Paz-Ferreiro, Jorge; Alves, Marlene Cristina; Vidal Vázquez, Eva

    2013-04-01

    Heterogeneity is now considered as an inherent soil property. Spatial variability of soil attributes in natural landscapes results mainly from soil formation factors. In cultivated soils much heterogeneity can additionally occur as a result of land use, agricultural systems and management practices. Organic matter content (OMC) and nutrients associated to soil exchange complex are key attribute in the maintenance of a high quality soil. Neglecting spatial heterogeneity in soil OMC and nutrient status at the field scale might result in reduced yield and in environmental damage. We analyzed the impact of land use on the pattern of spatial variability of OMC and soil macronutrients at the stand scale. The study was conducted in São Paulo state, Brazil. Land uses were pasture, mango orchard and corn field. Soil samples were taken at 0-10 cm and 10-20 cm depth in 84 points, within 100 m x 100 m plots. Texture, pH, OMC, cation exchange capacity (CEC), exchangeable cations (Ca, Mg, K, H, Al) and resin extractable phosphorus were analyzed.. Statistical variability was found to be higher in parameters defining the soil nutrient status (resin extractable P, K, Ca and Mg) than in general soil properties (OMC, CEC, base saturation and pH). Geostatistical analysis showed contrasting patterns of spatial dependence for the different soil uses, sampling depths and studied properties. Most of the studied data sets collected at two different depths exhibited spatial dependence at the sampled scale and their semivariograms were modeled by a nugget effect plus a structure. The pattern of soil spatial variability was found to be different between the three study soil uses and at the two sampling depths, as far as model type, nugget effect or ranges of spatial dependence were concerned. Both statistical and geostatistical results pointed out the importance of OMC as a driver responsible for the spatial variability of soil nutrient status.

  16. Distance and Azimuthal Dependence of Ground‐Motion Variability for Unilateral Strike‐Slip Ruptures

    KAUST Repository

    Vyas, Jagdish Chandra; Mai, Paul Martin; Galis, Martin

    2016-01-01

    We investigate near‐field ground‐motion variability by computing the seismic wavefield for five kinematic unilateral‐rupture models of the 1992 Mw 7.3 Landers earthquake, eight simplified unilateral‐rupture models based on the Landers event, and a

  17. Interpersonal dependency and online gaming addiction.

    Science.gov (United States)

    Škařupová, Kateřina; Blinka, Lukas

    2016-03-01

    Background and aims The present study explores the relationship between social motivations and addiction to online gaming and if that possible connection can be explained by the personality traits responsible for social functioning. Methods We employ Bernstein's concept of interpersonal dependency to distinguish healthy dependency, dysfunctional detachment, and destructive overdependence, and Charlton and Danforth's conceptualisation of online gaming addiction and high engagement. An online questionnaire was administered to a self-nominated sample of 4,074 online gamers. Two regression models were constructed to separately explain gaming addiction and high engagement using social motivations to play, while controlling for age, gender, and time spent online. Results High scores on subscales measuring dysfunctional detachment and destructive overdependence were positively associated with online gaming addiction, while healthy dependency was negatively correlated with addiction scores. In contrast, the overall role of social motivation was negligible. Discussion People with healthy relationship profiles are less likely to develop problematic patterns of online gaming. High in-game engagement, although sharing some factors with addiction, was only poorly explained by the study variables, suggesting the mutual exclusiveness of addiction and engagement.

  18. Risk variables in evaluation of transport projects

    Science.gov (United States)

    Vařbuchta, Petr; Kovářová, Hana; Hromádka, Vít; Vítková, Eva

    2017-09-01

    Depending on the constantly increasing demands on assessment of investment projects, especially assessment of large-scale projects in transport and important European projects with wide impacts, there is constantly increasing focus on risk management, whether to find mitigations, creating corrective measures or their implementation in assessment, especially in the context of Cost-Benefit analysis. To project assessment is often used implementation of certain risk variables, which can generate negative impacts of project outputs in framework of assess. Especially in case of transportation infrastructure projects is taken much emphasis on the influence of risk variables. However, currently in case of assessment of transportation projects is in Czech Republic used a few risk variables, which occur in the most projects. This leads to certain limitation in framework of impact assessment of risk variables. This papers aims to specify a new risk variables and process of applying them to already executed project assessment. Based on changes generated by new risk variables will be evaluated differences between original and adapted assessment.

  19. Reminiscence therapy using odor in alcohol-dependent patients--psychophysiological evaluation and psychological evaluation; power spectral analysis of heart rate variability.

    Science.gov (United States)

    Arizono, H; Morita, N; Iizuka, S; Satoh, S; Nakatani, Y

    2000-12-01

    This research was based on the hypothesis that when alcohol-dependent patients describe themselves, awakening of emotion by affirmative odor stimulation may facilitate memory reframing focusing on more affirmative emotion and memories. To prove the hypothesis, physiological changes accompanied by emotional awakening were evaluated by measuring the autonomic activity. In addition, subjective evaluation by a self-report manner was examined to investigate the effectiveness of Reminiscence Therapy (RT) using odor in alcohol-dependent patients. Thirty-four patients who met the DSM-IV criteria of alcohol-related disorders and were hospitalized in a ward specialized to alcohol dependence therapy. Each patient underwent a one-to-one interview twice. For counterbalance, one interview was performed with odor stimulation using an odor with a relaxing effect that recall pleasant emotion, and the other was without odor stimulation. As the evaluation indices of physiological changes accompanied by emotional awakening, index of autonomic function (HRV; Heart rate variability) for objective evaluation and psychological indices (STAI; State-Trait Anxiety Inventory VAS; Visual Analog Scale) for subjective evaluation were measured. 1) Objective evaluation: Regarding the evaluation index of the autonomic function, the sympathetic nervous system activity (LF/HF; low frequency component/high frequency component ratio) was significantly inhibited by odor stimulation (p Subjective evaluation: Compared to the state prior to interview, state anxiety judged by STAI was significantly decreased after interview (p subjective evaluation, but the objective evaluation suggested that the odor inhibited the sympathetic nervous system. Thus, it was suggested that odor can be used in RT, that is, emotional changes due to stimulation of odor may be applicable in RT.

  20. COMPARISON OF KEPLER PHOTOMETRIC VARIABILITY WITH THE SUN ON DIFFERENT TIMESCALES

    International Nuclear Information System (INIS)

    Basri, Gibor; Walkowicz, Lucianne M.; Reiners, Ansgar

    2013-01-01

    We utilize Kepler data to study the precision differential photometric variability of solar-type and cooler stars at different timescales, ranging from half an hour to three months. We define a diagnostic that characterizes the median differential intensity change between data bins of a given timescale. We apply the same diagnostics to Solar and Heliospheric Observatory data that has been rendered comparable to Kepler. The Sun exhibits similar photometric variability on all timescales as comparable solar-type stars in the Kepler field. The previously defined photometric ''range'' serves as our activity proxy (driven by starspot coverage). We revisit the fraction of comparable stars in the Kepler field that are more active than the Sun. The exact active fraction depends on what is meant by ''more active than the Sun'' and on the magnitude limit of the sample of stars considered. This active fraction is between a quarter and a third (depending on the timescale). We argue that a reliable result requires timescales of half a day or longer and stars brighter than M Kep of 14, otherwise non-stellar noise distorts it. We also analyze main sequence stars grouped by temperature from 6500 to 3500 K. As one moves to cooler stars, the active fraction of stars becomes steadily larger (greater than 90% for early M dwarfs). The Sun is a good photometric model at all timescales for those cooler stars that have long-term variability within the span of solar variability.

  1. Time-Dependent Drug Administration in Hypertension and its Effect on Blood Pressure Variability

    Directory of Open Access Journals (Sweden)

    Magdás Annamária

    2017-06-01

    Full Text Available Background: Optimizing blood pressure variability seems to represent a new therapeutic target in the management of hypertension. It is emphasized that scheduling at least one antihypertensive agent at bedtime, has the ability to reduce blood pressure.

  2. Space and time evolution of two nonlinearly coupled variables

    International Nuclear Information System (INIS)

    Obayashi, H.; Totsuji, H.; Wilhelmsson, H.

    1976-12-01

    The system of two coupled linear differential equations are studied assuming that the coupling terms are proportional to the product of the dependent variables, representing e.g. intensities or populations. It is furthermore assumed that these variables experience different linear dissipation or growth. The derivations account for space as well as time dependence of the variables. It is found that certain particular solutions can be obtained to this system, whereas a full solution in space and time as an initial value problem is outside the scope of the present paper. The system has a nonlinear equilibrium solution for which the nonlinear coupling terms balance the terms of linear dissipation. The case of space and time evolution of a small perturbation of the nonlinear equilibrium state, given the initial one-dimensional spatial distribution of the perturbation, is also considered in some detail. (auth.)

  3. An alternative approach to exact wave functions for time-dependent coupled oscillator model of charged particle in variable magnetic field

    International Nuclear Information System (INIS)

    Menouar, Salah; Maamache, Mustapha; Choi, Jeong Ryeol

    2010-01-01

    The quantum states of time-dependent coupled oscillator model for charged particles subjected to variable magnetic field are investigated using the invariant operator methods. To do this, we have taken advantage of an alternative method, so-called unitary transformation approach, available in the framework of quantum mechanics, as well as a generalized canonical transformation method in the classical regime. The transformed quantum Hamiltonian is obtained using suitable unitary operators and is represented in terms of two independent harmonic oscillators which have the same frequencies as that of the classically transformed one. Starting from the wave functions in the transformed system, we have derived the full wave functions in the original system with the help of the unitary operators. One can easily take a complete description of how the charged particle behaves under the given Hamiltonian by taking advantage of these analytical wave functions.

  4. Association between Serum Uric Acid Levels and Sleep Variables: Results from the National Health and Nutrition Survey 2005–2008

    Directory of Open Access Journals (Sweden)

    R. Constance Wiener

    2012-01-01

    Full Text Available Sleep disordered breathing as well as high serum uric acid levels are independent risk factors for cardiovascular disease. However, studies evaluating the relationship between sleep-disordered breathing and hyperuricemia are limited. We examined the 2005–2008 National Health and Nutrition Examination survey's sleep variables and high serum uric acid among 6491 participants aged ≥20 years. The sleep variables included sleep duration, snoring, snorting, and daytime sleepiness. The main outcome was high serum uric acid level, defined as levels of serum uric acid >6.8 mg/dL in males and >6.0 mg/dL in females. We found that snoring more than 5 nights per week, daytime sleepiness, and an additive composite score of sleep variables were associated with high serum uric acid in the age- , sex-adjusted model and in a multivariable model adjusting for demographic and lifestyle/behavioral risk factors. The association was attenuated with the addition of variables related to clinical outcomes such as depression, diabetes, hypertension, and high-cholesterol levels. Our results indicate a positive relationship between sleep variables, including the presence of snoring, snorting, and daytime sleepiness, and high serum uric acid levels.

  5. LandScape: a simple method to aggregate p--Values and other stochastic variables without a priori grouping

    DEFF Research Database (Denmark)

    Wiuf, Carsten; Pallesen, Jonatan; Foldager, Leslie

    2016-01-01

    variables without assuming a priori defined groups. We provide different ways to evaluate the significance of the aggregated variables based on theoretical considerations and resampling techniques, and show that under certain assumptions the FWER is controlled in the strong sense. Validity of the method...... and the results might depend on the chosen criteria. Methods that summarize, or aggregate, test statistics or p-values, without relying on a priori criteria, are therefore desirable. We present a simple method to aggregate a sequence of stochastic variables, such as test statistics or p-values, into fewer...

  6. Discrete-time BAM neural networks with variable delays

    Science.gov (United States)

    Liu, Xin-Ge; Tang, Mei-Lan; Martin, Ralph; Liu, Xin-Bi

    2007-07-01

    This Letter deals with the global exponential stability of discrete-time bidirectional associative memory (BAM) neural networks with variable delays. Using a Lyapunov functional, and linear matrix inequality techniques (LMI), we derive a new delay-dependent exponential stability criterion for BAM neural networks with variable delays. As this criterion has no extra constraints on the variable delay functions, it can be applied to quite general BAM neural networks with a broad range of time delay functions. It is also easy to use in practice. An example is provided to illustrate the theoretical development.

  7. Discrete-time BAM neural networks with variable delays

    International Nuclear Information System (INIS)

    Liu Xinge; Tang Meilan; Martin, Ralph; Liu Xinbi

    2007-01-01

    This Letter deals with the global exponential stability of discrete-time bidirectional associative memory (BAM) neural networks with variable delays. Using a Lyapunov functional, and linear matrix inequality techniques (LMI), we derive a new delay-dependent exponential stability criterion for BAM neural networks with variable delays. As this criterion has no extra constraints on the variable delay functions, it can be applied to quite general BAM neural networks with a broad range of time delay functions. It is also easy to use in practice. An example is provided to illustrate the theoretical development

  8. GENERAL APROACH TO MODELING NONLINEAR AMPLITUDE AND FREQUENCY DEPENDENT HYSTERESIS EFFECTS BASED ON EXPERIMENTAL RESULTS

    Directory of Open Access Journals (Sweden)

    Christopher Heine

    2014-08-01

    Full Text Available A detailed description of the rubber parts’ properties is gaining in importance in the current simulation models of multi-body simulation. One application example is a multi-body simulation of the washing machine movement. Inside the washing machine, there are different force transmission elements, which consist completely or partly of rubber. Rubber parts or, generally, elastomers usually have amplitude-dependant and frequency-dependent force transmission properties. Rheological models are used to describe these properties. A method for characterization of the amplitude and frequency dependence of such a rheological model is presented within this paper. Within this method, the used rheological model can be reduced or expanded in order to illustrate various non-linear effects. An original result is given with the automated parameter identification. It is fully implemented in Matlab. Such identified rheological models are intended for subsequent implementation in a multi-body model. This allows a significant enhancement of the overall model quality.

  9. Impacts of correcting the inter-variable correlation of climate model outputs on hydrological modeling

    Science.gov (United States)

    Chen, Jie; Li, Chao; Brissette, François P.; Chen, Hua; Wang, Mingna; Essou, Gilles R. C.

    2018-05-01

    Bias correction is usually implemented prior to using climate model outputs for impact studies. However, bias correction methods that are commonly used treat climate variables independently and often ignore inter-variable dependencies. The effects of ignoring such dependencies on impact studies need to be investigated. This study aims to assess the impacts of correcting the inter-variable correlation of climate model outputs on hydrological modeling. To this end, a joint bias correction (JBC) method which corrects the joint distribution of two variables as a whole is compared with an independent bias correction (IBC) method; this is considered in terms of correcting simulations of precipitation and temperature from 26 climate models for hydrological modeling over 12 watersheds located in various climate regimes. The results show that the simulated precipitation and temperature are considerably biased not only in the individual distributions, but also in their correlations, which in turn result in biased hydrological simulations. In addition to reducing the biases of the individual characteristics of precipitation and temperature, the JBC method can also reduce the bias in precipitation-temperature (P-T) correlations. In terms of hydrological modeling, the JBC method performs significantly better than the IBC method for 11 out of the 12 watersheds over the calibration period. For the validation period, the advantages of the JBC method are greatly reduced as the performance becomes dependent on the watershed, GCM and hydrological metric considered. For arid/tropical and snowfall-rainfall-mixed watersheds, JBC performs better than IBC. For snowfall- or rainfall-dominated watersheds, however, the two methods behave similarly, with IBC performing somewhat better than JBC. Overall, the results emphasize the advantages of correcting the P-T correlation when using climate model-simulated precipitation and temperature to assess the impact of climate change on watershed

  10. Observed and Unobserved Heterogeneity in the Duration Dependency Parameter

    DEFF Research Database (Denmark)

    Rosholm, Michael

    2000-01-01

    We present a duration model, which allows for non-homogenous duration dependence with respect to observed and unobserved variables. The model is examined in a simulation study, and it is estimated on unemployment spells of a sample of Danish workers. Udgivelsesdato: MAR......We present a duration model, which allows for non-homogenous duration dependence with respect to observed and unobserved variables. The model is examined in a simulation study, and it is estimated on unemployment spells of a sample of Danish workers. Udgivelsesdato: MAR...

  11. Implications of climate variability for the detection of multiple equilibria and for rapid transitions in the atmosphere-vegetation system

    Energy Technology Data Exchange (ETDEWEB)

    Bathiany, S. [Max Planck Institute for Meteorology, Hamburg (Germany); Claussen, M. [Max Planck Institute for Meteorology, Hamburg (Germany); Universitaet Hamburg, Meteorologisches Institut, Hamburg (Germany); Fraedrich, K. [Universitaet Hamburg, Meteorologisches Institut, Hamburg (Germany)

    2012-05-15

    Paleoclimatic records indicate a decline of vegetation cover in the Western Sahara at the end of the African Humid Period (about 5,500 years before present). Modelling studies have shown that this phenomenon may be interpreted as a critical transition that results from a bifurcation in the atmosphere-vegetation system. However, the stability properties of this system are closely linked to climate variability and depend on the climate model and the methods of analysis. By coupling the Planet Simulator (PlaSim), an atmosphere model of intermediate complexity, with the simple dynamic vegetation model VECODE, we assess previous methods for the detection of multiple equilibria, and demonstrate their limitations. In particular, a stability diagram can yield misleading results because of spatial interactions, and the system's steady state and its dependency on initial conditions are affected by atmospheric variability and nonlinearities. In addition, we analyse the implications of climate variability for the abruptness of a vegetation decline. We find that a vegetation collapse can happen at different locations at different times. These collapses are possible despite large and uncorrelated climate variability. Because of the nonlinear relation between vegetation dynamics and precipitation the green state is initially stabilised by the high variability. When precipitation falls below a critical threshold, the desert state is stabilised as variability is then also decreased. (orig.)

  12. A Structural Equation Approach to Models with Spatial Dependence

    NARCIS (Netherlands)

    Oud, Johan H. L.; Folmer, Henk

    We introduce the class of structural equation models (SEMs) and corresponding estimation procedures into a spatial dependence framework. SEM allows both latent and observed variables within one and the same (causal) model. Compared with models with observed variables only, this feature makes it

  13. A structural equation approach to models with spatial dependence

    NARCIS (Netherlands)

    Oud, J.H.L.; Folmer, H.

    2008-01-01

    We introduce the class of structural equation models (SEMs) and corresponding estimation procedures into a spatial dependence framework. SEM allows both latent and observed variables within one and the same (causal) model. Compared with models with observed variables only, this feature makes it

  14. A Structural Equation Approach to Models with Spatial Dependence

    NARCIS (Netherlands)

    Oud, J.H.L.; Folmer, H.

    2008-01-01

    We introduce the class of structural equation models (SEMs) and corresponding estimation procedures into a spatial dependence framework. SEM allows both latent and observed variables within one and the same (causal) model. Compared with models with observed variables only, this feature makes it

  15. Multilevel Cross-Dependent Binary Longitudinal Data

    KAUST Repository

    Serban, Nicoleta; Staicu, Ana-Maria; Carroll, Raymond J.

    2013-01-01

    processes describing the within- and between-variability, and describing the cross-dependence of the repeated longitudinal measurements. We estimate the model components without employing mixed-effects modeling but assuming an approximation to the logistic

  16. Multivariate quantile mapping bias correction: an N-dimensional probability density function transform for climate model simulations of multiple variables

    Science.gov (United States)

    Cannon, Alex J.

    2018-01-01

    Most bias correction algorithms used in climatology, for example quantile mapping, are applied to univariate time series. They neglect the dependence between different variables. Those that are multivariate often correct only limited measures of joint dependence, such as Pearson or Spearman rank correlation. Here, an image processing technique designed to transfer colour information from one image to another—the N-dimensional probability density function transform—is adapted for use as a multivariate bias correction algorithm (MBCn) for climate model projections/predictions of multiple climate variables. MBCn is a multivariate generalization of quantile mapping that transfers all aspects of an observed continuous multivariate distribution to the corresponding multivariate distribution of variables from a climate model. When applied to climate model projections, changes in quantiles of each variable between the historical and projection period are also preserved. The MBCn algorithm is demonstrated on three case studies. First, the method is applied to an image processing example with characteristics that mimic a climate projection problem. Second, MBCn is used to correct a suite of 3-hourly surface meteorological variables from the Canadian Centre for Climate Modelling and Analysis Regional Climate Model (CanRCM4) across a North American domain. Components of the Canadian Forest Fire Weather Index (FWI) System, a complicated set of multivariate indices that characterizes the risk of wildfire, are then calculated and verified against observed values. Third, MBCn is used to correct biases in the spatial dependence structure of CanRCM4 precipitation fields. Results are compared against a univariate quantile mapping algorithm, which neglects the dependence between variables, and two multivariate bias correction algorithms, each of which corrects a different form of inter-variable correlation structure. MBCn outperforms these alternatives, often by a large margin

  17. Sensitivity of Photosynthetic Gas Exchange and Growth of Lodgepole Pine to Climate Variability Depends on the Age of Pleistocene Glacial Surfaces

    Science.gov (United States)

    Osborn, B.; Chapple, W.; Ewers, B. E.; Williams, D. G.

    2014-12-01

    The interaction between soil conditions and climate variability plays a central role in the ecohydrological functions of montane conifer forests. Although soil moisture availability to trees is largely dependent on climate, the depth and texture of soil exerts a key secondary influence. Multiple Pleistocene glacial events have shaped the landscape of the central Rocky Mountains creating a patchwork of soils differing in age and textural classification. This mosaic of soil conditions impacts hydrological properties, and montane conifer forests potentially respond to climate variability quite differently depending on the age of glacial till and soil development. We hypothesized that the age of glacial till and associated soil textural changes exert strong control on growth and photosynthetic gas exchange of lodgepole pine. We examined physiological and growth responses of lodgepole pine to interannual variation in maximum annual snow water equivalence (SWEmax) of montane snowpack and growing season air temperature (Tair) and vapor pressure deficit (VPD) across a chronosequence of Pleistocene glacial tills ranging in age from 700k to 12k years. Soil textural differences across the glacial tills illustrate the varying degrees of weathering with the most well developed soils with highest clay content on the oldest till surfaces. We show that sensitivity of growth and carbon isotope discrimination, an integrated measure of canopy gas exchange properties, to interannual variation SWEmax , Tair and VPD is greatest on young till surfaces, whereas trees on old glacial tills with well-developed soils are mostly insensitive to these interannual climate fluctuations. Tree-ring widths were most sensitive to changes in SWEmax on young glacial tills (p < 0.01), and less sensitive on the oldest till (p < 0.05). Tair correlates strongly with δ13C values on the oldest and youngest tills sites, but shows no significant relationship on the middle aged glacial till. It is clear that

  18. Vaccine induced antibodies to the first variable loop of human immunodeficiency virus type 1 gp120, mediate antibody-dependent virus inhibition in macaques.

    Science.gov (United States)

    Bialuk, Izabela; Whitney, Stephen; Andresen, Vibeke; Florese, Ruth H; Nacsa, Janos; Cecchinato, Valentina; Valeri, Valerio W; Heraud, Jean-Michel; Gordon, Shari; Parks, Robyn Washington; Montefiori, David C; Venzon, David; Demberg, Thorsten; Guroff, Marjorie Robert-; Landucci, Gary; Forthal, Donald N; Franchini, Genoveffa

    2011-12-09

    The role of antibodies directed against the hyper variable envelope region V1 of human immunodeficiency virus type 1 (HIV-1), has not been thoroughly studied. We show that a vaccine able to elicit strain-specific non-neutralizing antibodies to this region of gp120 is associated with control of highly pathogenic chimeric SHIV(89.6P) replication in rhesus macaques. The vaccinated animal that had the highest titers of antibodies to the amino terminus portion of V1, prior to challenge, had secondary antibody responses that mediated cell killing by antibody-dependent cellular cytotoxicity (ADCC), as early as 2 weeks after infection and inhibited viral replication by antibody-dependent cell-mediated virus inhibition (ADCVI), by 4 weeks after infection. There was a significant inverse correlation between virus level and binding antibody titers to the envelope protein, (R=-0.83, p=0.015), and ADCVI (R=-0.84 p=0.044). Genotyping of plasma virus demonstrated in vivo selection of three SHIV(89.6P) variants with changes in potential N-linked glycosylation sites in V1. We found a significant inverse correlation between virus levels and titers of antibodies that mediated ADCVI against all the identified V1 virus variants. A significant inverse correlation was also found between neutralizing antibody titers to SHIV(89.6) and virus levels (R=-0.72 p=0.0050). However, passive inoculation of purified immunoglobulin from animal M316, the macaque that best controlled virus, to a naïve macaque, resulted in a low serum neutralizing antibodies and low ADCVI activity that failed to protect from SHIV(89.6P) challenge. Collectively, while our data suggest that anti-envelope antibodies with neutralizing and non-neutralizing Fc(R-dependent activities may be important in the control of SHIV replication, they also demonstrate that low levels of these antibodies alone are not sufficient to protect from infection. Published by Elsevier Ltd.

  19. Heliocentric distance dependence of the interplanetary magnetic field

    International Nuclear Information System (INIS)

    Behannon, K.W.

    1978-01-01

    Recent and ongoing planetary missions have provided and are continuing to provide extensive observations of the variations of the interplanetary magnetic field (IMF) both in time and with heliocentric distance from the sun. Large time variations in both the IMF and its fluctuations are observed. These are produced predominantly by dynamical processes in the interplanetary medium associated with stream interactions. Magnetic field variations near the sun are propagated to greater heliocentric distances, a process also contributing to the observed variability of the IMF. Temporal variations on a time scale comparable to or less than the corotation period complicate attempts to deduce radial gradients of the field and its fluctuations from the various observations. However, recent measurements inward to 0.46 AU and outward to 5 AU suggest that the radial component of the field on average decreases approximately as r -2 , as was predicted by Parker, while the azimuthal component decreases more rapidly than the r -1 dependence predicted by simple theory. Three sets of observations are consistent with r/sup -1.3/ dependence for vertical-barB/sub phi/vertical-bar. The temporal variability of solar wind speed is most likely the predominant contributor to this latter observational result. The long-term average azimuthal component radial gradient is probably consistent with the Parker r -1 dependence when solar wind speed variations are taken into account. The observations of the normal component magnitude vertical-barB/sub theta/vertical-bar are roughly consistent with a heliocentric distance dependence of r/sup -1.4/. The observed radial distance dependence of the total magnitude of the IMF is well described by the Parker formulation. There is observational evidence that amplitudes of fluctuations of the vector field with periods less than 1 day vary with heliocentric distance as approximately r/sup -3/2/, in agreement with theoretical models by Whang and Hollweg

  20. Thermodynamic consistency of viscoplastic material models involving external variable rates in the evolution equations for the internal variables

    International Nuclear Information System (INIS)

    Malmberg, T.

    1993-09-01

    The objective of this study is to derive and investigate thermodynamic restrictions for a particular class of internal variable models. Their evolution equations consist of two contributions: the usual irreversible part, depending only on the present state, and a reversible but path dependent part, linear in the rates of the external variables (evolution equations of ''mixed type''). In the first instance the thermodynamic analysis is based on the classical Clausius-Duhem entropy inequality and the Coleman-Noll argument. The analysis is restricted to infinitesimal strains and rotations. The results are specialized and transferred to a general class of elastic-viscoplastic material models. Subsequently, they are applied to several viscoplastic models of ''mixed type'', proposed or discussed in the literature (Robinson et al., Krempl et al., Freed et al.), and it is shown that some of these models are thermodynamically inconsistent. The study is closed with the evaluation of the extended Clausius-Duhem entropy inequality (concept of Mueller) where the entropy flux is governed by an assumed constitutive equation in its own right; also the constraining balance equations are explicitly accounted for by the method of Lagrange multipliers (Liu's approach). This analysis is done for a viscoplastic material model with evolution equations of the ''mixed type''. It is shown that this approach is much more involved than the evaluation of the classical Clausius-Duhem entropy inequality with the Coleman-Noll argument. (orig.) [de

  1. A similarity solution of time dependent MHD liquid film flow over stretching sheet with variable physical properties

    Science.gov (United States)

    Idrees, M.; Rehman, Sajid; Shah, Rehan Ali; Ullah, M.; Abbas, Tariq

    2018-03-01

    An analysis is performed for the fluid dynamics incorporating the variation of viscosity and thermal conductivity on an unsteady two-dimensional free surface flow of a viscous incompressible conducting fluid taking into account the effect of a magnetic field. Surface tension quadratically vary with temperature while fluid viscosity and thermal conductivity are assumed to vary as a linear function of temperature. The boundary layer partial differential equations in cartesian coordinates are transformed into a system of nonlinear ordinary differential equations (ODEs) by similarity transformation. The developed nonlinear equations are solved analytically by Homotopy Analysis Method (HAM) while numerically by using the shooting method. The Effects of natural parameters such as the variable viscosity parameter A, variable thermal conductivity parameter N, Hartmann number Ma, film Thickness, unsteadiness parameter S, Thermocapillary number M and Prandtl number Pr on the velocity and temperature profiles are investigated. The results for the surface skin friction coefficient f″ (0) , Nusselt number (heat flux) -θ‧ (0) and free surface temperature θ (1) are presented graphically and in tabular form.

  2. Time-dependent theoretical model of the polar wind: Preliminary results

    International Nuclear Information System (INIS)

    Gombosi, T.I.; Cravens, T.E.; Nagy, A.F.

    1985-01-01

    The coupled time dependent continuity, momentum and energy equations of a two ion (O + and H + ) quasineutral plasma were solved in order to extend our understanding of polar wind behavior. This numerical code allows studies of the time dependent behavior of polar wind-type flows into and out of the ionosphere. Initial studies indicate that the typical time constants for electron and ion temperature changes are of the order of minutes and tens of minutes, respectively. The response time of the minor high altitude ion O + is less than an hour, whereas that of the major ion, H + , is many hours. The initial test runs also demonstrate the fact that temporary supersonic flows of both O + and H + are possible, especially in the presence of significant ion heating

  3. Intraspecific variability of European larch for wood properties: Preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Paques, L.E.; Rozenberg, P. [Institut National de Recherches Agronomiques (INRA), 45 - Olivet (France). Station d`Amelioration des Arbres Forestiers

    1995-12-31

    Wood properties of several natural populations of European larch (Larix decidua Mill) were determined from samples collected in one replicate of the II. International IUFRO provenance experiment, planted in Brittany in 1959. According to provenances, proportion of heartwood ranges from 35 to 58% of basal area, basic density from 442 to 505 g/dm{sup 3} and Young modulus of elasticity from 8474 to 14522 MPa. Positive correlations between girth and heartwood proportion and between wood density and modulus of elasticity but negative correlations between ring width and both density and MOE have been found both at the individual and at the population levels. Variability between and within provenances is high for two major traits (proportion of heartwood and Young modulus of elasticity) for which a SW - NE gradient is shown. For wood density parameters including pilodyn, a greater homogeneity is observed. Besides a now largely recognized superiority for growth traits, Central European populations from the Sudetan Mountains and Central Poland would also produce wood with better properties. On the reverse, Alpine populations from the French Alps growing at low elevations have a slower growth, a denser wood with less heartwood and less strength. Used as a control, the hybrid larch origin (Larix x eurolepis) represents the best compromise for wood properties with the highest strength but an average wood density and one of the highest proportion of heartwood. These preliminary results must be confirmed from a larger set of provenances and completed with other major wood properties such as durability and shrinkage. 17 refs, 2 figs, 6 tabs

  4. Intraspecific variability of European larch for wood properties: Preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Paques, L E; Rozenberg, P [Institut National de Recherches Agronomiques (INRA), 45 - Olivet (France). Station d` Amelioration des Arbres Forestiers

    1996-12-31

    Wood properties of several natural populations of European larch (Larix decidua Mill) were determined from samples collected in one replicate of the II. International IUFRO provenance experiment, planted in Brittany in 1959. According to provenances, proportion of heartwood ranges from 35 to 58% of basal area, basic density from 442 to 505 g/dm{sup 3} and Young modulus of elasticity from 8474 to 14522 MPa. Positive correlations between girth and heartwood proportion and between wood density and modulus of elasticity but negative correlations between ring width and both density and MOE have been found both at the individual and at the population levels. Variability between and within provenances is high for two major traits (proportion of heartwood and Young modulus of elasticity) for which a SW - NE gradient is shown. For wood density parameters including pilodyn, a greater homogeneity is observed. Besides a now largely recognized superiority for growth traits, Central European populations from the Sudetan Mountains and Central Poland would also produce wood with better properties. On the reverse, Alpine populations from the French Alps growing at low elevations have a slower growth, a denser wood with less heartwood and less strength. Used as a control, the hybrid larch origin (Larix x eurolepis) represents the best compromise for wood properties with the highest strength but an average wood density and one of the highest proportion of heartwood. These preliminary results must be confirmed from a larger set of provenances and completed with other major wood properties such as durability and shrinkage. 17 refs, 2 figs, 6 tabs

  5. Signal or noise? Separating grain size-dependent Nd isotope variability from provenance shifts in Indus delta sediments, Pakistan

    Science.gov (United States)

    Jonell, T. N.; Li, Y.; Blusztajn, J.; Giosan, L.; Clift, P. D.

    2017-12-01

    Rare earth element (REE) radioisotope systems, such as neodymium (Nd), have been traditionally used as powerful tracers of source provenance, chemical weathering intensity, and sedimentary processes over geologic timescales. More recently, the effects of physical fractionation (hydraulic sorting) of sediments during transport have called into question the utility of Nd isotopes as a provenance tool. Is source terrane Nd provenance resolvable if sediment transport strongly induces noise? Can grain-size sorting effects be quantified? This study works to address such questions by utilizing grain size analysis, trace element geochemistry, and Nd isotope geochemistry of bulk and grain-size fractions (Pakistan. Here we evaluate how grain size effects drive Nd isotope variability and further resolve the total uncertainties associated with Nd isotope compositions of bulk sediments. Results from the Indus delta indicate bulk sediment ɛNd compositions are most similar to the <63 µm fraction as a result of strong mineralogical control on bulk compositions by silt- to clay-sized monazite and/or allanite. Replicate analyses determine that the best reproducibility (± 0.15 ɛNd points) is observed in the 125-250 µm fraction. The bulk and finest fractions display the worst reproducibility (±0.3 ɛNd points). Standard deviations (2σ) indicate that bulk sediment uncertainties are no more than ±1.0 ɛNd points. This argues that excursions of ≥1.0 ɛNd points in any bulk Indus delta sediments must in part reflect an external shift in provenance irrespective of sample composition, grain size, and grain size distribution. Sample standard deviations (2s) estimate that any terrigenous bulk sediment composition should vary no greater than ±1.1 ɛNd points if provenance remains constant. Findings from this study indicate that although there are grain-size dependent Nd isotope effects, they are minimal in the Indus delta such that resolvable provenance-driven trends can be

  6. Linear elastic obstacles: analysis of experimental results in the case of stress dependent pre-exponentials

    International Nuclear Information System (INIS)

    Surek, T.; Kuon, L.G.; Luton, M.J.; Jones, J.J.

    1975-01-01

    For the case of linear elastic obstacles, the analysis of experimental plastic flow data is shown to have a particularly simple form when the pre-exponential factor is a single-valued function of the modulus-reduced stress. The analysis permits the separation of the stress and temperature dependence of the strain rate into those of the pre-exponential factor and the activation free energy. As a consequence, the true values of the activation enthalpy, volume and entropy also are obtained. The approach is applied to four sets of experimental data, including Zr, and the results for the pre-exponential term are examined for self-consistency in view of the assumed functional dependence

  7. High variability impairs motor learning regardless of whether it affects task performance.

    Science.gov (United States)

    Cardis, Marco; Casadio, Maura; Ranganathan, Rajiv

    2018-01-01

    Motor variability plays an important role in motor learning, although the exact mechanisms of how variability affects learning are not well understood. Recent evidence suggests that motor variability may have different effects on learning in redundant tasks, depending on whether it is present in the task space (where it affects task performance) or in the null space (where it has no effect on task performance). We examined the effect of directly introducing null and task space variability using a manipulandum during the learning of a motor task. Participants learned a bimanual shuffleboard task for 2 days, where their goal was to slide a virtual puck as close as possible toward a target. Critically, the distance traveled by the puck was determined by the sum of the left- and right-hand velocities, which meant that there was redundancy in the task. Participants were divided into five groups, based on both the dimension in which the variability was introduced and the amount of variability that was introduced during training. Results showed that although all groups were able to reduce error with practice, learning was affected more by the amount of variability introduced rather than the dimension in which variability was introduced. Specifically, groups with higher movement variability during practice showed larger errors at the end of practice compared with groups that had low variability during learning. These results suggest that although introducing variability can increase exploration of new solutions, this may adversely affect the ability to retain the learned solution. NEW & NOTEWORTHY We examined the role of introducing variability during motor learning in a redundant task. The presence of redundancy allows variability to be introduced in different dimensions: the task space (where it affects task performance) or the null space (where it does not affect task performance). We found that introducing variability affected learning adversely, but the amount of

  8. Action-angle variables for the massless relativistic string in 1+1 dimensions

    International Nuclear Information System (INIS)

    Soederberg, B.; Andersson, B.; Gustafson, G.

    1985-01-01

    In this paper the Poisson bracket algebra for the open massless relativistic string in the one-space- and one-time-dimensional case is considered. In order to characterize the orbit of the system the directrix function, i.e., the orbit of one of the endpoints of the string, is used. It turns out that the Poisson bracket algebra is of a very simple form in terms of the parameters of the directrix function. We use these results to construct action-angle variables for the general motion of the string. The variables are different for different Lorentz frames, with a continuous dependence. The action-angle variables of the center-of-mass frame and of the light-cone frames are of particular interest with respect to the simplicity of the Poincare generators and the physical interpretation. For the light-cone frame variables the equivalence to a set of indistinguishable oscillators is shown, for which an excitation corresponds to an instantaneous momentum transfer to an endpoint of the string

  9. Psychiatric comorbidity and quality of life in patients with alcohol dependence syndrome

    Directory of Open Access Journals (Sweden)

    Sidharth Arya

    2017-01-01

    Full Text Available Context: There is a lack of literature on the relation between psychiatric comorbidities and their influence on quality of life in patients with alcohol dependence syndrome in the Indian settings. Aims: To study the relation between psychiatric comorbidity with quality of life in patients with alcohol dependence. Settings and Design: The study was carried out in a de-addiction centre of a tertiary care hospital upon randomly selected inpatients of alcohol dependence syndrome. Patients with other substance abuse except tobacco or those with severe physical impairment were excluded. Materials and Methods: Hundred in-patients were assessed between the period of August 2013 to July 2014, using a number of instruments including specially designed proforma for clinical and drinking variables, CIWA-Ar, SADD, M.I.N.I 5.0 and WHO QoL Bref. Statistics used: SPSS 19.0 was used for analysis. Significance was calculated using t-test for continuous variables and chi-square test for categorical variables. Results: Prevalence of psychiatric disorder was found to be 32% across all the tested patients, with anxiety (n = 13 and depressive disorder (n = 12 being most common. Presence of psychiatric comorbidity lead to significant lowering in overall quality, perception of general health, physical (42.12 vs 57.78, P = 0.001, psychological (40.19 vs 53.29, P = 0.002, social (43.97 vs 66.90, P = 0.000, and environment (50.47 vs 62.71, P = 0.001 domains. Conclusion: Comorbid psychiatric disorders have a significant negative impact on the quality of life in patients with alcohol dependence syndrome.

  10. Effects of short-term variability of meteorological variables on soil temperature in permafrost regions

    Science.gov (United States)

    Beer, Christian; Porada, Philipp; Ekici, Altug; Brakebusch, Matthias

    2018-03-01

    Effects of the short-term temporal variability of meteorological variables on soil temperature in northern high-latitude regions have been investigated. For this, a process-oriented land surface model has been driven using an artificially manipulated climate dataset. Short-term climate variability mainly impacts snow depth, and the thermal diffusivity of lichens and bryophytes. These impacts of climate variability on insulating surface layers together substantially alter the heat exchange between atmosphere and soil. As a result, soil temperature is 0.1 to 0.8 °C higher when climate variability is reduced. Earth system models project warming of the Arctic region but also increasing variability of meteorological variables and more often extreme meteorological events. Therefore, our results show that projected future increases in permafrost temperature and active-layer thickness in response to climate change will be lower (i) when taking into account future changes in short-term variability of meteorological variables and (ii) when representing dynamic snow and lichen and bryophyte functions in land surface models.

  11. Rate dependent inelastic behavior of polycrystalline solids using a dislocation model

    International Nuclear Information System (INIS)

    Werne, R.W.; Kelly, J.M.

    1980-01-01

    A rate dependent theory of polycrystalline plasticity is presented in which the solid is modeled as an isotropic continuum with internal variables. The rate of plastic deformation is shown to be a function of the deviatoric portion of the Cauchy stress tensor as well as two scalar internal variables. The scalar internal variables, which are the dislocation density and mobile fraction, are governed by rate equations which reflect the evolution of microstructural processes. The model has been incorporated into a two dimensional finite element code and several example multidimensional problems are presented which exhibit the rate dependence of the material model

  12. HIV-1 subtype A gag variability and epitope evolution.

    Directory of Open Access Journals (Sweden)

    Syed Hani Abidi

    Full Text Available OBJECTIVE: The aim of this study was to examine the course of time-dependent evolution of HIV-1 subtype A on a global level, especially with respect to the dynamics of immunogenic HIV gag epitopes. METHODS: We used a total of 1,893 HIV-1 subtype A gag sequences representing a timeline from 1985 through 2010, and 19 different countries in Africa, Europe and Asia. The phylogenetic relationship of subtype A gag and its epidemic dynamics was analysed through a Maximum Likelihood tree and Bayesian Skyline plot, genomic variability was measured in terms of G → A substitutions and Shannon entropy, and the time-dependent evolution of HIV subtype A gag epitopes was examined. Finally, to confirm observations on globally reported HIV subtype A sequences, we analysed the gag epitope data from our Kenyan, Pakistani, and Afghan cohorts, where both cohort-specific gene epitope variability and HLA restriction profiles of gag epitopes were examined. RESULTS: The most recent common ancestor of the HIV subtype A epidemic was estimated to be 1956 ± 1. A period of exponential growth began about 1980 and lasted for approximately 7 years, stabilized for 15 years, declined for 2-3 years, then stabilized again from about 2004. During the course of evolution, a gradual increase in genomic variability was observed that peaked in 2005-2010. We observed that the number of point mutations and novel epitopes in gag also peaked concurrently during 2005-2010. CONCLUSION: It appears that as the HIV subtype A epidemic spread globally, changing population immunogenetic pressures may have played a role in steering immune-evolution of this subtype in new directions. This trend is apparent in the genomic variability and epitope diversity of HIV-1 subtype A gag sequences.

  13. HEART RATE VARIABILITY PARAMETERS IN PATIENTS WITH ARTERIAL HYPERTENSION IN DEPENDENCE ON THE TYPE OF DAILY BLOOD PRESSURE PROFILE

    Directory of Open Access Journals (Sweden)

    S. G. B. K. Gorantla

    2017-06-01

    Full Text Available Violation of functioning of the autonomic nervous system is an important factor in the formation and progression of arterial hypertension (AH. Abnormal nocturnal blood pressure (BP reduction is regarded as an independent prognostic factor for cardiovascular complications in patients with AH. One of the possible factors that determine the violation of BP circadian rhythm can be imbalance of different parts of autonomic nervous system. The aim of our study was to study heart rate variability (HRV in patients with AH, dependently of BP profile. 72 patients with AH were examined. Average age was 57 ± 11 years. All patients underwent ambulatory BP (ABPM and ECG monitoring. To define the daily profile the nocturnal BP dip was quantified and for HRV evaluation the frequency analysis method was used. HRV changes in patients with AH present with reduced total power and with a violation in the ratio of the powers of very low, low and high frequencies, enhanced sympathycotension and influence of humoral factors. Violations of systolic BP (SBP daily profile was mainly characterized by an increase in the power of low frequency waves, which indicates an intensification of sympathetic and decreased parasympathetic influences. Violations of diastolic BP (DBP daily profile were mainly characterized by a relative increase in the power of very low frequency waves. The obtained results showed that in the management of patients with AH it is important not only to control the circadian SBP and DBP profiles, but the evaluation of HRV also.

  14. Spatial scales of pollution from variable resolution satellite imaging.

    Science.gov (United States)

    Chudnovsky, Alexandra A; Kostinski, Alex; Lyapustin, Alexei; Koutrakis, Petros

    2013-01-01

    The Moderate Resolution Imaging Spectroradiometer (MODIS) provides daily global coverage, but the 10 km resolution of its aerosol optical depth (AOD) product is not adequate for studying spatial variability of aerosols in urban areas. Recently, a new Multi-Angle Implementation of Atmospheric Correction (MAIAC) algorithm was developed for MODIS which provides AOD at 1 km resolution. Using MAIAC data, the relationship between MAIAC AOD and PM(2.5) as measured by the EPA ground monitoring stations was investigated at varying spatial scales. Our analysis suggested that the correlation between PM(2.5) and AOD decreased significantly as AOD resolution was degraded. This is so despite the intrinsic mismatch between PM(2.5) ground level measurements and AOD vertically integrated measurements. Furthermore, the fine resolution results indicated spatial variability in particle concentration at a sub-10 km scale. Finally, this spatial variability of AOD within the urban domain was shown to depend on PM(2.5) levels and wind speed. Copyright © 2012 Elsevier Ltd. All rights reserved.

  15. Heat conduction in a plate-type fuel element with time-dependent boundary conditions

    International Nuclear Information System (INIS)

    Faya, A.J.G.; Maiorino, J.R.

    1981-01-01

    A method for the solution of boundary-value problems with variable boundary conditions is applied to solve a heat conduction problem in a plate-type fuel element with time dependent film coefficient. The numerical results show the feasibility of the method in the solution of this class of problems. (Author) [pt

  16. The relationship between species richness and ecosystem variability is shaped by the mechanism of coexistence.

    Science.gov (United States)

    Tredennick, Andrew T; Adler, Peter B; Adler, Frederick R

    2017-08-01

    Theory relating species richness to ecosystem variability typically ignores the potential for environmental variability to promote species coexistence. Failure to account for fluctuation-dependent coexistence may explain deviations from the expected negative diversity-ecosystem variability relationship, and limits our ability to predict the consequences of increases in environmental variability. We use a consumer-resource model to explore how coexistence via the temporal storage effect and relative nonlinearity affects ecosystem variability. We show that a positive, rather than negative, diversity-ecosystem variability relationship is possible when ecosystem function is sampled across a natural gradient in environmental variability and diversity. We also show how fluctuation-dependent coexistence can buffer ecosystem functioning against increasing environmental variability by promoting species richness and portfolio effects. Our work provides a general explanation for variation in observed diversity-ecosystem variability relationships and highlights the importance of conserving regional species pools to help buffer ecosystems against predicted increases in environmental variability. © 2017 John Wiley & Sons Ltd/CNRS.

  17. ANALYSIS OF THE DEPENDENCE OF THE E-LEARNING USAGE ON THE STUDY RESULTS

    Directory of Open Access Journals (Sweden)

    KUNCOVÁ, M.

    2015-03-01

    Full Text Available The main aim of this paper is to compare the study results of the selected subjects of the full time and combined forms of study at the study programme Economics and Management. This programme is offered at the College of Polytechnics Jihlava and covers two fields of study - Travel and Tourism, Finance and Management. The comparison is aimed at the results of the period before the start of the e-learning (2008 for full time students and 2010 for combined form with the year 2012 (after the e-learning implementation. The results from eight biggest subjects are tested via Chi-square test of independence. It should answer the question if the e-learning has had an impact on the study results and if it is possible to find dependence between results of two different types of study, two different years, two different study branches and two different subjects. The comparison has shown the differences of combined/full time students but we have not proved the influence of the e-learning on the evaluation.

  18. Pair copula constructions to determine the dependence structure of Treasury bond yields

    Directory of Open Access Journals (Sweden)

    Marcelo Brutti Righi

    2015-12-01

    Full Text Available We estimated the dependence structure of US Treasury bonds through a pair copula construction. As a result, we verified that the variability of the yields decreases with a longer time of maturity of the bond. The yields presented strong dependence with past values, strongly positive bivariate associations between the daily variations, and prevalence of the Student's t copula in the relationships between the bonds. Furthermore, in tail associations, we identified relevant values in most of the relationships, which highlights the importance of risk management in the context of bonds diversification.

  19. Low-frequency photospheric and wind variability in the early-B supergiant HD2905

    DEFF Research Database (Denmark)

    Simon-Diaz, S.; Aerts, C.; Urbaneja, M. A.

    2018-01-01

    to the lack of adequate observations for a proper characterization of the complex spectroscopic and photometric variability occurring in these stars. Aims. Our goal is to detect, analyze, and interpret variability in the early-B-type supergiant HD2905 (kappa Cas, B1 Ia) using long-term, ground-based, high...... snapshot and time-dependent information about the stellar parameters and abundances by means of the FASTWIND stellar atmosphere code. Results. HD2905 is a spectroscopic variable with peak-to-peak amplitudes in the zero and first moments of the photospheric lines of up to 15% and 30 km s(-1), respectively....... Conclusions. Combined long-term uninterrupted space photometry with high-precision spectroscopy is the best strategy to unravel the complex low-frequency photospheric and wind variability of B supergiants. Three-dimensional (3D) simulations of waves and of convective motions in the sub-surface layers can shed...

  20. A geometric model for magnetizable bodies with internal variables

    Directory of Open Access Journals (Sweden)

    Restuccia, L

    2005-11-01

    Full Text Available In a geometrical framework for thermo-elasticity of continua with internal variables we consider a model of magnetizable media previously discussed and investigated by Maugin. We assume as state variables the magnetization together with its space gradient, subjected to evolution equations depending on both internal and external magnetic fields. We calculate the entropy function and necessary conditions for its existence.

  1. Risk of dependence associated with health, social support, and lifestyle.

    Science.gov (United States)

    Alcañiz, Manuela; Brugulat, Pilar; Guillén, Montserrat; Medina-Bustos, Antonia; Mompart-Penina, Anna; Solé-Auró, Aïda

    2015-01-01

    OBJECTIVE To analyze the prevalence of individuals at risk of dependence and its associated factors. METHODS The study was based on data from the Catalan Health Survey, Spain conducted in 2010 and 2011. Logistic regression models from a random sample of 3,842 individuals aged ≥ 15 years were used to classify individuals according to the state of their personal autonomy. Predictive models were proposed to identify indicators that helped distinguish dependent individuals from those at risk of dependence. Variables on health status, social support, and lifestyles were considered. RESULTS We found that 18.6% of the population presented a risk of dependence, especially after age 65. Compared with this group, individuals who reported dependence (11.0%) had difficulties performing activities of daily living and had to receive support to perform them. Habits such as smoking, excessive alcohol consumption, and being sedentary were associated with a higher probability of dependence, particularly for women. CONCLUSIONS Difficulties in carrying out activities of daily living precede the onset of dependence. Preserving personal autonomy and function without receiving support appear to be a preventive factor. Adopting an active and healthy lifestyle helps reduce the risk of dependence.

  2. On the K-term and dispersion ratios of semi-regular variables

    International Nuclear Information System (INIS)

    Aslan, Z.

    1981-01-01

    Optical velocities of semi-regular (SR) and irregular (Lb) variables are analysed for a K-term. There is evidence for a dependence upon stellar period. Absorption lines in shorter period non-emission SR variables are blue-shifted relative to the centre-of-mass velocity by about 6 +- 3 km s -1 . Emission-line SR variables give a non-negative absorption K-term and Lb variables give no K-terms other than zero. Comparison is made with the K-terms implied by the OH velocity pattern in long-period variables. Dispersion ratios are also calculated. (author)

  3. Estimations of natural variability between satellite measurements of trace species concentrations

    Science.gov (United States)

    Sheese, P.; Walker, K. A.; Boone, C. D.; Degenstein, D. A.; Kolonjari, F.; Plummer, D. A.; von Clarmann, T.

    2017-12-01

    In order to validate satellite measurements of atmospheric states, it is necessary to understand the range of random and systematic errors inherent in the measurements. On occasions where the measurements do not agree within those errors, a common "go-to" explanation is that the unexplained difference can be chalked up to "natural variability". However, the expected natural variability is often left ambiguous and rarely quantified. This study will look to quantify the expected natural variability of both O3 and NO2 between two satellite instruments: ACE-FTS (Atmospheric Chemistry Experiment - Fourier Transform Spectrometer) and OSIRIS (Optical Spectrograph and Infrared Imaging System). By sampling the CMAM30 (30-year specified dynamics simulation of the Canadian Middle Atmosphere Model) climate chemistry model throughout the upper troposphere and stratosphere at times and geolocations of coincident ACE-FTS and OSIRIS measurements at varying coincidence criteria, height-dependent expected values of O3 and NO2 variability will be estimated and reported on. The results could also be used to better optimize the coincidence criteria used in satellite measurement validation studies.

  4. Bounding the conservatism in flaw-related variables for pressure vessel integrity analyses

    International Nuclear Information System (INIS)

    Foulds, J.R.; Kennedy, E.L.

    1993-01-01

    The fracture mechanics-based integrity analysis of a pressure vessel, whether performed deterministically or probabilistically, requires use of one or more flaw-related input variables, such as flaw size, number of flaws, flaw location, and flaw type. The specific values of these variables are generally selected with the intent to ensure conservative predictions of vessel integrity. These selected values, however, are largely independent of vessel-specific inspection results, or are, at best, deduced by ''conservative'' interpretation of vessel-specific inspection results without adequate consideration of the pertinent inspection system performance (reliability). In either case, the conservatism associated with the flaw-related variables chosen for analysis remains examination (NDE) technology and the recently formulated ASME Code procedures for qualifying NDE system capability and performance (as applied to selected nuclear power plant components) now provides a systematic means of bounding the conservatism in flaw-related input variables for pressure vessel integrity analyses. This is essentially achieved by establishing probabilistic (risk)-based limits on the assigned variable values, dependent upon the vessel inspection results and on the inspection system unreliability. Described herein is this probabilistic method and its potential application to: (i) defining a vessel-specific ''reference'' flaw for calculating pressure-temperature limit curves in the deterministic evaluation of pressurized water reactor (PWR) reactor vessels, and (ii) limiting the flaw distribution input to a PWR reactor vessel-specific, probabilistic integrity analysis for pressurized thermal shock loads

  5. Variability in Measured Space Temperatures in 60 Homes

    Energy Technology Data Exchange (ETDEWEB)

    Roberts, D.; Lay, K.

    2013-03-01

    This report discusses the observed variability in indoor space temperature in a set of 60 homes located in Florida, New York, Oregon, and Washington. Temperature data were collected at 15-minute intervals for an entire year, including living room, master bedroom, and outdoor air temperature (Arena, et. al). The data were examined to establish the average living room temperature for the set of homes for the heating and cooling seasons, the variability of living room temperature depending on climate, and the variability of indoor space temperature within the homes. The accuracy of software-based energy analysis depends on the accuracy of input values. Thermostat set point is one of the most influential inputs for building energy simulation. Several industry standards exist that recommend differing default thermostat settings for heating and cooling seasons. These standards were compared to the values calculated for this analysis. The data examined for this report show that there is a definite difference between the climates and that the data do not agree well with any particular standard.

  6. Effects of Webquest on the achievement and motivation on Jordanian university students of (Independent & Dependent cognitive style

    Directory of Open Access Journals (Sweden)

    Osamah Mohammad Ameen Aldalalah

    2015-08-01

    Full Text Available The purpose of this study was to investigate the effects of webquest on the jordanian students’ of different cognitive style. The independent variables were the instruction (conventional & webquest. The dependent variables were the students’ achievement and motivation. The instructionrating variable is cognitive style (independent & dependent. The study sample consisted of 72 undergraduate educational technology students, information and communication technology students and graphic design students. Inferential statistics were conducted to analyze the data. An analysis of covariance (ANCOVA and T-TEST was carried out to examine the main effects of the independent variables on the dependent variables. The findings of this study showed that students using the webquest instruction performed significantly better on achievement and motivation than students using the conventional instruction. Independent cognitive style students performed significantly better on achievement and motivation than dependent cognitive style students. The webquest instruction was found to help students with dependent cognitive style on achievement and motivation

  7. Contextuality is about identity of random variables

    International Nuclear Information System (INIS)

    Dzhafarov, Ehtibar N; Kujala, Janne V

    2014-01-01

    Contextual situations are those in which seemingly ‘the same’ random variable changes its identity depending on the conditions under which it is recorded. Such a change of identity is observed whenever the assumption that the variable is one and the same under different conditions leads to contradictions when one considers its joint distribution with other random variables (this is the essence of all Bell-type theorems). In our Contextuality-by-Default approach, instead of asking why or how the conditions force ‘one and the same’ random variable to change ‘its’ identity, any two random variables recorded under different conditions are considered different ‘automatically.’ They are never the same, nor are they jointly distributed, but one can always impose on them a joint distribution (probabilistic coupling). The special situations when there is a coupling in which these random variables are equal with probability 1 are considered noncontextual. Contextuality means that such couplings do not exist. We argue that the determination of the identity of random variables by conditions under which they are recorded is not a causal relationship and cannot violate laws of physics. (paper)

  8. Antimicrobial breakpoint estimation accounting for variability in pharmacokinetics

    Directory of Open Access Journals (Sweden)

    Nekka Fahima

    2009-06-01

    Full Text Available Abstract Background Pharmacokinetic and pharmacodynamic (PK/PD indices are increasingly being used in the microbiological field to assess the efficacy of a dosing regimen. In contrast to methods using MIC, PK/PD-based methods reflect in vivo conditions and are more predictive of efficacy. Unfortunately, they entail the use of one PK-derived value such as AUC or Cmax and may thus lead to biased efficiency information when the variability is large. The aim of the present work was to evaluate the efficacy of a treatment by adjusting classical breakpoint estimation methods to the situation of variable PK profiles. Methods and results We propose a logical generalisation of the usual AUC methods by introducing the concept of "efficiency" for a PK profile, which involves the efficacy function as a weight. We formulated these methods for both classes of concentration- and time-dependent antibiotics. Using drug models and in silico approaches, we provide a theoretical basis for characterizing the efficiency of a PK profile under in vivo conditions. We also used the particular case of variable drug intake to assess the effect of the variable PK profiles generated and to analyse the implications for breakpoint estimation. Conclusion Compared to traditional methods, our weighted AUC approach gives a more powerful PK/PD link and reveals, through examples, interesting issues about the uniqueness of therapeutic outcome indices and antibiotic resistance problems.

  9. Continuous-variable quantum computing on encrypted data

    DEFF Research Database (Denmark)

    Marshall, Kevin; Jacobsen, Christian Scheffmann; Schäfermeier, Clemens

    2016-01-01

    in the sense that they are dependent on a hacker's computational power. Here we theoretically investigate, and experimentally demonstrate with Gaussian displacement and squeezing operations, a quantum solution that achieves the security of a user's privacy using the practical technology of continuous variables...

  10. Individual Variability in Brain Activity: A Nuisance or an Opportunity?

    Science.gov (United States)

    Van Horn, John Darrell; Grafton, Scott T; Miller, Michael B

    2008-12-01

    Functional imaging research has been heavily influenced by results based on population-level inference. However, group average results may belie the unique patterns of activity present in the individual that ordinarily are considered random noise. Recent advances in the evolution of MRI hardware have led to significant improvements in the stability and reproducibility of blood oxygen level dependent (BOLD) measurements. These enhancements provide a unique opportunity for closer examination of individual patterns of brain activity. Three objectives can be accomplished by considering brain scans at the individual level; (1) Mapping functional anatomy at a fine grained analysis; (2) Determining if an individual scan is normative with respect to a reference population; and (3) Understanding the sources of intersubject variability in brain activity. In this review, we detail these objectives, briefly discuss their histories and present recent trends in the analyses of individual variability. Finally, we emphasize the unique opportunities and challenges for understanding individual differences through international collaboration among Pacific Rim investigators.

  11. Ruin Probabilities in a Dependent Discrete-Time Risk Model With Gamma-Like Tailed Insurance Risks

    Directory of Open Access Journals (Sweden)

    Xing-Fang Huang

    2017-03-01

    Full Text Available This paper considered a dependent discrete-time risk model, in which the insurance risks are represented by a sequence of independent and identically distributed real-valued random variables with a common Gamma-like tailed distribution; the financial risks are denoted by another sequence of independent and identically distributed positive random variables with a finite upper endpoint, but a general dependence structure exists between each pair of the insurance risks and the financial risks. Following the works of Yang and Yuen in 2016, we derive some asymptotic relations for the finite-time and infinite-time ruin probabilities. As a complement, we demonstrate our obtained result through a Crude Monte Carlo (CMC simulation with asymptotics.

  12. Imaging Variable Stars with HST

    Science.gov (United States)

    Karovska, M.

    2012-06-01

    (Abstract only) The Hubble Space Telescope (HST) observations of astronomical sources, ranging from objects in our solar system to objects in the early Universe, have revolutionized our knowledge of the Universe its origins and contents. I highlight results from HST observations of variable stars obtained during the past twenty or so years. Multiwavelength observations of numerous variable stars and stellar systems were obtained using the superb HST imaging capabilities and its unprecedented angular resolution, especially in the UV and optical. The HST provided the first detailed images probing the structure of variable stars including their atmospheres and circumstellar environments. AAVSO observations and light curves have been critical for scheduling of many of these observations and provided important information and context for understanding of the imaging results of many variable sources. I describe the scientific results from the imaging observations of variable stars including AGBs, Miras, Cepheids, semiregular variables (including supergiants and giants), YSOs and interacting stellar systems with a variable stellar components. These results have led to an unprecedented understanding of the spatial and temporal characteristics of these objects and their place in the stellar evolutionary chains, and in the larger context of the dynamic evolving Universe.

  13. Possible Origin of Stagnation and Variability of Earth's Biodiversity

    Science.gov (United States)

    Stollmeier, Frank; Geisel, Theo; Nagler, Jan

    2014-06-01

    The magnitude and variability of Earth's biodiversity have puzzled scientists ever since paleontologic fossil databases became available. We identify and study a model of interdependent species where both endogenous and exogenous impacts determine the nonstationary extinction dynamics. The framework provides an explanation for the qualitative difference of marine and continental biodiversity growth. In particular, the stagnation of marine biodiversity may result from a global transition from an imbalanced to a balanced state of the species dependency network. The predictions of our framework are in agreement with paleontologic databases.

  14. Variable screening and ranking using sampling-based sensitivity measures

    International Nuclear Information System (INIS)

    Wu, Y-T.; Mohanty, Sitakanta

    2006-01-01

    This paper presents a methodology for screening insignificant random variables and ranking significant important random variables using sensitivity measures including two cumulative distribution function (CDF)-based and two mean-response based measures. The methodology features (1) using random samples to compute sensitivities and (2) using acceptance limits, derived from the test-of-hypothesis, to classify significant and insignificant random variables. Because no approximation is needed in either the form of the performance functions or the type of continuous distribution functions representing input variables, the sampling-based approach can handle highly nonlinear functions with non-normal variables. The main characteristics and effectiveness of the sampling-based sensitivity measures are investigated using both simple and complex examples. Because the number of samples needed does not depend on the number of variables, the methodology appears to be particularly suitable for problems with large, complex models that have large numbers of random variables but relatively few numbers of significant random variables

  15. Interpersonal dependency and online gaming addiction

    Science.gov (United States)

    Škařupová, Kateřina; Blinka, Lukas

    2016-01-01

    Background and aims The present study explores the relationship between social motivations and addiction to online gaming and if that possible connection can be explained by the personality traits responsible for social functioning. Methods We employ Bernstein’s concept of interpersonal dependency to distinguish healthy dependency, dysfunctional detachment, and destructive overdependence, and Charlton and Danforth’s conceptualisation of online gaming addiction and high engagement. An online questionnaire was administered to a self-nominated sample of 4,074 online gamers. Two regression models were constructed to separately explain gaming addiction and high engagement using social motivations to play, while controlling for age, gender, and time spent online. Results High scores on subscales measuring dysfunctional detachment and destructive overdependence were positively associated with online gaming addiction, while healthy dependency was negatively correlated with addiction scores. In contrast, the overall role of social motivation was negligible. Discussion People with healthy relationship profiles are less likely to develop problematic patterns of online gaming. High in-game engagement, although sharing some factors with addiction, was only poorly explained by the study variables, suggesting the mutual exclusiveness of addiction and engagement. PMID:26690326

  16. Phase variable expression of a single phage receptor in Campylobacter jejuni NCTC12662 influences sensitivity toward several diverse CPS-dependent phages

    DEFF Research Database (Denmark)

    Gencay, Yilmaz Emre; Sørensen, Martine C.H.; Wenzel, Cory Q.

    2018-01-01

    Campylobacter jejuni NCTC12662 is sensitive to infection by many Campylobacter bacteriophages. Here we used this strain to investigate the molecular mechanism behind phage resistance development when exposed to a single phage and demonstrate how phase variable expression of one surface component...... influences phage sensitivity against many diverse C. jejuni phages. When C. jejuni NCTC12662 was exposed to phage F207 overnight, 25% of the bacterial cells were able to grow on a lawn of phage F207, suggesting that resistance develops at a high frequency. One resistant variant, 12662R, was further...... characterized and shown to be an adsorption mutant. Plaque assays using our large phage collection showed that seven out of 36 diverse capsular polysaccharide (CPS)-dependent phages could not infect 12662R, whereas the remaining phages formed plaques on 12662R with reduced efficiencies. Analysis of the CPS...

  17. VARIABLE STARS IN THE LARGE MAGELLANIC CLOUD GLOBULAR CLUSTER NGC 2257. I. RESULTS BASED ON 2007-2008 B, V PHOTOMETRY

    International Nuclear Information System (INIS)

    Nemec, James M.; Walker, Alistair; Jeon, Young-Beom

    2009-01-01

    The variable stars in the Large Magellanic Cloud star cluster NGC 2257 are reinvestigated using photometry (to ∼20th mag) of over 400 new B, V CCD images taken with the CTIO 0.9 m telescope on 14 nights in 2007 December and 2008 January. New period searches have been made using two independent algorithms (CLEAN, Period04); the resultant periods of most of the stars are consistent with the pulsation periods derived previously, and where there are discrepancies these have been resolved. For the B and V light curves, accurate Fourier coefficients and parameters are given. Six new variable stars have been discovered (V45-50), including a bright candidate long-period variable star showing secondary oscillations (V45) and two anomalously bright RRc stars (V48 and V50), which are shown to be brightened and reddened by nearby red giant stars. Also discovered among the previously known variable stars are three double-mode RR Lyrae stars (V8, V16, and V34) and several Blazhko variables. Archival Hubble Space Telescope images and the photometry by Johnson et al. have been used to define better the properties of the most crowded variable stars. The total number of cluster variable stars now stands at forty-seven: 23 RRab stars, four of which show Blazhko amplitude variations; 20 RRc stars, one showing clear Blazhko variations and another showing possible Blazhko variations; the three RRd stars, all having the dominant period ∼0.36 day and period ratios P 1 /P 0 ∼0.7450; and an LPV star located near the tip of the red giant branch. A comparison of the RRd stars with those in other environments shows them to be most similar to those in IC4499.

  18. Structural dependence of the galvanomagnetic properties of transition-metal aluminide thin films

    CERN Document Server

    Kim, K W; Jeong, M H; Lee, Y P; Rhee, J Y

    1999-01-01

    The structural dependences of the galvanomagnetic properties of Co-Al and Fe-Al alloy films were investigated in this study. Ordered and disordered alloy films with thickness of 150 nm were prepared by using the flash evaporation technique on the heated and cooled substrates, respectively. The temperature dependence of resistance was measured in the range of 2 approx 300 K range with and without a magnetic field of 0.5 T. The influence of the order-disorder structural transition on the temperature dependence of the resistance is discussed in connection with the results for the magnetic properties and is analyzed in the framework of the partial localization of the electronic states and variable-range hopping conductivity.

  19. Variability: A Pernicious Hypothesis.

    Science.gov (United States)

    Noddings, Nel

    1992-01-01

    The hypothesis of greater male variability in test results is discussed in its historical context, and reasons feminists have objected to the hypothesis are considered. The hypothesis acquires political importance if it is considered that variability results from biological, rather than cultural, differences. (SLD)

  20. Behaviors Predicting Foot Lesions in Patients with Non-Insulin-Dependent Diabetes Mellitus

    OpenAIRE

    Suico, Jeffrey G; Marriott, Deanna J; Vinicor, Frank; Litzelman, Debra K

    1998-01-01

    Associations between specific foot-care behaviors and foot lesions in patients with non-insulin-dependent diabetes mellitus were prospectively investigated. Data from a randomized controlled trial for preventing diabetic foot lesions were analyzed as a prospective cohort using logistic regression. Independent variables included foot-care behaviors, patient self-foot examination, going barefoot, availability of foot-care assistance, and visits to health-care providers. The dependent variable w...

  1. Existence and controllability results for damped second order impulsive functional differential systems with state-dependent delay

    Directory of Open Access Journals (Sweden)

    M. Mallika Arjunan

    2014-01-01

    Full Text Available In this paper, we investigate the existence and controllability of mild solutions for a damped second order impulsive functional differential equation with state-dependent delay in Banach spaces. The results are obtained by using Sadovskii's fixed point theorem combined with the theories of a strongly continuous cosine family of bounded linear operators. Finally, an example is provided to illustrate the main results.

  2. Spatio-temporal variability of soil respiration in a spruce-dominated headwater catchment in western Germany

    Science.gov (United States)

    Bossa, A. Y.; Diekkrüger, B.

    2014-08-01

    CO2 production and transport from forest floors is an important component of the carbon cycle and is closely related to the global atmosphere CO2 concentration. If we are to understand the feedback between soil processes and atmospheric CO2, we need to know more about the spatio-temporal variability of this soil respiration under different environmental conditions. In this study, long-term measurements were conducted in a spruce-dominated forest ecosystem in western Germany. Multivariate analysis-based similarities between different measurement sites led to the detection of site clusters along two CO2 emission axes: (1) mainly controlled by soil temperature and moisture condition, and (2) mainly controlled by root biomass and the forest floor litter. The combined effects of soil temperature and soil moisture were used as a time-dependent rating factor affecting the optimal CO2 production and transport at cluster level. High/moderate/weak time-dependent rating factors were associated with the different clusters. The process-based, most distant clusters were identified using specified pattern characteristics: the reaction rates in the soil layers, the activation energy for bio-chemical reactions, the soil moisture dependency parameter, the root biomass factor, the litter layer factor and the organic matter factor. A HYDRUS-1D model system was inversely used to compute soil hydraulic parameters from soil moisture measurements. Heat transport parameters were calibrated based on observed soil temperatures. The results were used to adjust CO2 productions by soil microorganisms and plant roots under optimal conditions for each cluster. Although the uncertainty associated with the HYDRUS-1D simulations is higher, the results were consistent with both the multivariate clustering and the time-dependent rating of site production. Finally, four clusters with significantly different environmental conditions (i.e. permanent high soil moisture condition, accumulated litter amount

  3. Environmental Literacy in Madeira Island (Portugal): The Influence of Demographic Variables

    Science.gov (United States)

    Spinola, Hélder

    2016-01-01

    Demographic factors are among those that influence environmental literacy and, particularly, environmentally responsible behaviours, either directly or due to an aggregation effect dependent on other types of variables. Present study evaluates a set of demographic variables as predictors for environmental literacy among 9th grade students from…

  4. Climate variability and yields of major staple food crops in Northern ...

    African Journals Online (AJOL)

    Conversely, agriculture is a major contributor to climate variability and change by emitting greenhouse gases and reducing the agroecology's potential for carbon sequestration. What however, is the empirical evidence of this inter-dependence of climate variability and agriculture in Sub-Sahara Africa? In this paper, we ...

  5. Comparing Personality Traits , Coping Strategies, and Attributional Styles of Opioid-Dependent Patients and Healthy People

    Directory of Open Access Journals (Sweden)

    Afsaneh Moradi

    2011-04-01

    Full Text Available Objective: This study is carried on to compare personality traits, coping strategies, and attributional styles of opiate-dependent patients and healthy people. Materials & Methods: In this cross-sctional and comparative research, three scales Eysenk Personality Questionaire RS (EPQ-RS, Coping Response Inventory (CRI, and Attributional Style Questionnaire (ASQ are used to measure the mentioned variables on 158 people (78 opiate-dependent patient and 80 healthy people selected by accessible sampling method. Research data were examined on the basis of T-test for independent groups and logistic regression. Results: Results of T-test showed that there were significant differences between healthy and patient group in Coping Response Inventory and Personality Traits Subscale(except Lying subscale and attribution styles for negative events (P<0.001. Logistic regression results showed that all of these variables which entered in model, are able to predict distinction one group from other patient group and healthy one in a meaningful way(P<0.001. Conclusion: opiate-dependent patients when they face problems significantly use problem-solving strategies, social support seeking, and cognitive evaluation significantly less than healthy group and use physical inhibition and emotional inhibition significantly more than the healthy group. Also, drug-dependent patients in terms of tendency to Neuroticism, psychoticism and introversion were significantly higher than the healthy group, and they had more pessimistic attributional style towards negative events. On the other hand it became apparent that some aspects of personality characteristics, coping strategies, and attributional style considerably were able to distinguish healthy people from opiate-dependent patients.

  6. Improved variable reduction in partial least squares modelling by Global-Minimum Error Uninformative-Variable Elimination.

    Science.gov (United States)

    Andries, Jan P M; Vander Heyden, Yvan; Buydens, Lutgarde M C

    2017-08-22

    The calibration performance of Partial Least Squares regression (PLS) can be improved by eliminating uninformative variables. For PLS, many variable elimination methods have been developed. One is the Uninformative-Variable Elimination for PLS (UVE-PLS). However, the number of variables retained by UVE-PLS is usually still large. In UVE-PLS, variable elimination is repeated as long as the root mean squared error of cross validation (RMSECV) is decreasing. The set of variables in this first local minimum is retained. In this paper, a modification of UVE-PLS is proposed and investigated, in which UVE is repeated until no further reduction in variables is possible, followed by a search for the global RMSECV minimum. The method is called Global-Minimum Error Uninformative-Variable Elimination for PLS, denoted as GME-UVE-PLS or simply GME-UVE. After each iteration, the predictive ability of the PLS model, built with the remaining variable set, is assessed by RMSECV. The variable set with the global RMSECV minimum is then finally selected. The goal is to obtain smaller sets of variables with similar or improved predictability than those from the classical UVE-PLS method. The performance of the GME-UVE-PLS method is investigated using four data sets, i.e. a simulated set, NIR and NMR spectra, and a theoretical molecular descriptors set, resulting in twelve profile-response (X-y) calibrations. The selective and predictive performances of the models resulting from GME-UVE-PLS are statistically compared to those from UVE-PLS and 1-step UVE, one-sided paired t-tests. The results demonstrate that variable reduction with the proposed GME-UVE-PLS method, usually eliminates significantly more variables than the classical UVE-PLS, while the predictive abilities of the resulting models are better. With GME-UVE-PLS, a lower number of uninformative variables, without a chemical meaning for the response, may be retained than with UVE-PLS. The selectivity of the classical UVE method

  7. Model atmospheres with periodic shocks. [pulsations and mass loss in variable stars

    Science.gov (United States)

    Bowen, G. H.

    1989-01-01

    The pulsation of a long-period variable star generates shock waves which dramatically affect the structure of the star's atmosphere and produce conditions that lead to rapid mass loss. Numerical modeling of atmospheres with periodic shocks is being pursued to study the processes involved and the evolutionary consequences for the stars. It is characteristic of these complex dynamical systems that most effects result from the interaction of various time-dependent processes.

  8. Scaling behavior and variable hopping conductivity in the quantum Hall plateau transition

    International Nuclear Information System (INIS)

    Tu, Tao; Zhao, Yong-Jie; Guo, Guo-Ping; Hao, Xiao-Jie; Guo, Guang-Can

    2007-01-01

    We have measured the temperature dependence of the longitudinal resistivity ρ xx of a two-dimensional electron system in the regime of the quantum Hall plateau transition. We extracted the quantitative form of scaling function for ρ xx and compared it with the results of ordinary scaling theory and variable range hopping based theory. We find that the two alternative theoretically proposed scaling functions are valid in different regions

  9. Mechanics of deformations in terms of scalar variables

    Science.gov (United States)

    Ryabov, Valeriy A.

    2017-05-01

    Theory of particle and continuous mechanics is developed which allows a treatment of pure deformation in terms of the set of variables "coordinate-momentum-force" instead of the standard treatment in terms of tensor-valued variables "strain-stress." This approach is quite natural for a microscopic description of atomic system, according to which only pointwise forces caused by the stress act to atoms making a body deform. The new concept starts from affine transformation of spatial to material coordinates in terms of the stretch tensor or its analogs. Thus, three principal stretches and three angles related to their orientation form a set of six scalar variables to describe deformation. Instead of volume-dependent potential used in the standard theory, which requires conditions of equilibrium for surface and body forces acting to a volume element, a potential dependent on scalar variables is introduced. A consistent introduction of generalized force associated with this potential becomes possible if a deformed body is considered to be confined on the surface of torus having six genuine dimensions. Strain, constitutive equations and other fundamental laws of the continuum and particle mechanics may be neatly rewritten in terms of scalar variables. Giving a new presentation for finite deformation new approach provides a full treatment of hyperelasticity including anisotropic case. Derived equations of motion generate a new kind of thermodynamical ensemble in terms of constant tension forces. In this ensemble, six internal deformation forces proportional to the components of Irving-Kirkwood stress are controlled by applied external forces. In thermodynamical limit, instead of the pressure and volume as state variables, this ensemble employs deformation force measured in kelvin unit and stretch ratio.

  10. IDENTIFICATION OF THOSE VARIABLES THAT HAVE A SIGNIFICANT INFLUENCE ON THE EXPECTED NUMBER OF DAYS OF STAYING IN THE CENTRE DEVELOPMENT REGION OF ROMANIA

    Directory of Open Access Journals (Sweden)

    Erika KULCSÁR

    2010-06-01

    Full Text Available I started from the assumption that there are more variables that have a significant influence on the expected number of days of staying in the Centre Development Region. To identify those variables this paper includes the analysis of variance with two variables that are not interacting, in this case the dependent variable is the question "How many days did you plan to stay in Centre Development Region?" and the independent variables are: "What is the purpose of your stay?" "What is the highest level of education?". Given that there are cases when interactions occur between variables, I also analyzed the interaction effects between the two independent variables. The paper also includes an ANOVA analysis with three variables between which interactions relationships occur. After identifying the dependency relations between the variables I found that the inclusion of the third variable, namely the "Marital status" of respondents, adds value to the model. Following the results obtained by ANOVA analysis, I identified those socio-demographic characteristics that, in my opinion, companies that operate on tourist market in the Center Development Region should consider when fundamenting marketing strategies in tourism.

  11. POVMs and hidden variables

    International Nuclear Information System (INIS)

    Stairs, Allen

    2007-01-01

    Recent results by Paul Busch and Adan Cabello claim to show that by appealing to POVMs, non-contextual hidden variables can be ruled out in two dimensions. While the results of Busch and Cabello are mathematically correct, interpretive problems render them problematic as no hidden variable proofs

  12. Constrained variability of modeled T:ET ratio across biomes

    Science.gov (United States)

    Fatichi, Simone; Pappas, Christoforos

    2017-07-01

    A large variability (35-90%) in the ratio of transpiration to total evapotranspiration (referred here as T:ET) across biomes or even at the global scale has been documented by a number of studies carried out with different methodologies. Previous empirical results also suggest that T:ET does not covary with mean precipitation and has a positive dependence on leaf area index (LAI). Here we use a mechanistic ecohydrological model, with a refined process-based description of evaporation from the soil surface, to investigate the variability of T:ET across biomes. Numerical results reveal a more constrained range and higher mean of T:ET (70 ± 9%, mean ± standard deviation) when compared to observation-based estimates. T:ET is confirmed to be independent from mean precipitation, while it is found to be correlated with LAI seasonally but uncorrelated across multiple sites. Larger LAI increases evaporation from interception but diminishes ground evaporation with the two effects largely compensating each other. These results offer mechanistic model-based evidence to the ongoing research about the patterns of T:ET and the factors influencing its magnitude across biomes.

  13. Compound Poisson Approximations for Sums of Random Variables

    OpenAIRE

    Serfozo, Richard F.

    1986-01-01

    We show that a sum of dependent random variables is approximately compound Poisson when the variables are rarely nonzero and, given they are nonzero, their conditional distributions are nearly identical. We give several upper bounds on the total-variation distance between the distribution of such a sum and a compound Poisson distribution. Included is an example for Markovian occurrences of a rare event. Our bounds are consistent with those that are known for Poisson approximations for sums of...

  14. Angular-dependent EDMR linewidth for spin-dependent space charge limited conduction in a polycrystalline pentacene

    Science.gov (United States)

    Fukuda, Kunito; Asakawa, Naoki

    2017-08-01

    Spin-dependent space charge limited carrier conduction in a Schottky barrier diode using polycrystalline p-type π-conjugated molecular pentacene is explored using multiple-frequency electrically detected magnetic resonance (EDMR) spectroscopy with a variable-angle configuration. The measured EDMR spectra are decomposed into two components derived respectively from mobile and trapped positive polarons. The linewidth of the EDMR signal for the trapped polarons increases with increasing resonance magnetic field for an in-plane configuration where the normal vector of the device substrate is perpendicular to the resonance magnetic field, while it is independent of the field for an out-of-plane configuration. This difference is consistent with the pentacene arrangement on the device substrate, where pentacene molecules exhibit a uniaxial orientation on the out-of-substrate plane. By contrast, the mobile polarons do not show anisotropic behavior with respect to the resonance magnetic field, indicating that the anisotropic effect is averaged out owing to carrier motion. These results suggest that the orientational arrangements of polycrystalline pentacene molecules in a nano thin film play a crucial role in spin-dependent electrical conduction.

  15. MODELING OF RELATIONSHIP BETWEEN GROUNDWATER FLOW AND OTHER METEOROLOGICAL VARIABLES USING FUZZY LOGIC

    Directory of Open Access Journals (Sweden)

    Şaban YURTÇU

    2006-02-01

    Full Text Available In this study, modeling of the effect of rainfall, flow and evaporation as independent variables on the change of underground water levels as dependent variables were investigated by fuzzy logic (FL. In the study, total 396 values taken from six observation stations belong to Afyon inferior basin in Akarçay from 1977 to 1989 years were used. Using the monthly average values of stations, the change of underground water level was modeled by FL. It is observed that the results obtained from FL and the observations are compatible with each other. This shows FL modeling can be used to estimate groundwater levels from the appropriate meteorological value.

  16. Variables that Predict Serve Efficacy in Elite Men's Volleyball with Different Quality of Opposition Sets.

    Science.gov (United States)

    Valhondo, Álvaro; Fernández-Echeverría, Carmen; González-Silva, Jara; Claver, Fernando; Moreno, M Perla

    2018-03-01

    The objective of this study was to determine the variables that predicted serve efficacy in elite men's volleyball, in sets with different quality of opposition. 3292 serve actions were analysed, of which 2254 were carried out in high quality of opposition sets and 1038 actions were in low quality of opposition sets, corresponding to a total of 24 matches played during the Men's European Volleyball Championships held in 2011. The independent variables considered in this study were the serve zone, serve type, serving player, serve direction, reception zone, receiving player and reception type; the dependent variable was serve efficacy and the situational variable was quality of opposition sets. The variables that acted as predictors in both high and low quality of opposition sets were the serving player, reception zone and reception type. The serve type variable only acted as a predictor in high quality of opposition sets, while the serve zone variable only acted as a predictor in low quality of opposition sets. These results may provide important guidance in men's volleyball training processes.

  17. Influence of attrition variables on iron ore flotation

    Directory of Open Access Journals (Sweden)

    Fabiana Fonseca Fortes

    Full Text Available Abstract The presence of slimes is harmful to the flotation process: the performance and consumption of reagents are negatively affected. Traditionally, the desliming stage has been responsible for removing slimes. However, depending on the porosity of the mineral particles, desliming may not be sufficient to maximize the concentration results. An attrition process before the desliming operation can improve the removal of slime, especially when slimes cover the surface and/or are confined to the cavities/pores of the mineral particles. Attrition is present in the flowcharts of the beneficiation process of phosphate and industrial sand (silica sand. Research has been undertaken for its application to produce pre-concentrates of zircon and iron ore. However, there is still little knowledge of the influence of the attrition variables on the beneficiation process of iron ore. This study presents a factorial design and analysis of the effects of these variables on the reverse flotation of iron ore. The standard of the experimental procedures for all tests included the attrition of pulp, under the conditions of dispersion, desliming and flotation. The parameter analysed (variable response was the metallurgical recovery in reverse flotation tests. The planning and analysis of the full factorial experiment indicated that with 95% reliability, the rotation speed of the attrition cell impeller was the main variable in the attrition process of the iron ore. The percentage of solid variables in the pulp and the time of the attrition, as well as their interactions, were not indicated to be significant.

  18. PHOTOMETRY OF VARIABLE STARS FROM DOME A, ANTARCTICA: RESULTS FROM THE 2010 OBSERVING SEASON

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Lingzhi; Zhu, Zonghong [Department of Astronomy, Beijing Normal University, Beijing 100875 (China); Macri, Lucas M.; Wang, Lifan [Mitchell Institute for Fundamental Physics and Astronomy, Department of Physics and Astronomy, Texas A and M University, College Station, TX 77843 (United States); Ashley, Michael C. B.; Lawrence, Jon S.; Luong-Van, Daniel; Storey, John W. V. [School of Physics, University of New South Wales, NSW 2052 (Australia); Cui, Xiangqun; Feng, Long-Long; Gong, Xuefei; Liu, Qiang; Shang, Zhaohui; Yang, Huigen; Yang, Ji; Yuan, Xiangyan; Zhou, Xu; Zhu, Zhenxi [Chinese Center for Antarctic Astronomy, Nanjing 210008 (China); Pennypacker, Carl R. [Center for Astrophysics, Lawrence Berkeley National Laboratory, Berkeley, CA (United States); York, Donald G., E-mail: wanglingzhi@bao.ac.cn [Department of Astronomy and Astrophysics and Enrico Fermi Institute, University of Chicago, Chicago, IL 60637 (United States)

    2013-12-01

    We present results from a season of observations with the Chinese Small Telescope ARray, obtained over 183 days of the 2010 Antarctic winter. We carried out high-cadence time-series aperture photometry of 9125 stars with i ∼< 15.3 mag located in a 23 deg{sup 2} region centered on the south celestial pole. We identified 188 variable stars, including 67 new objects relative to our 2008 observations, thanks to broader synoptic coverage, a deeper magnitude limit, and a larger field of view. We used the photometric data set to derive site statistics from Dome A. Based on two years of observations, we find that extinction due to clouds at this site is less than 0.1 and 0.4 mag during 45% and 75% of the dark time, respectively.

  19. Spatial scales of pollution from variable resolution satellite imaging

    International Nuclear Information System (INIS)

    Chudnovsky, Alexandra A.; Kostinski, Alex; Lyapustin, Alexei; Koutrakis, Petros

    2013-01-01

    The Moderate Resolution Imaging Spectroradiometer (MODIS) provides daily global coverage, but the 10 km resolution of its aerosol optical depth (AOD) product is not adequate for studying spatial variability of aerosols in urban areas. Recently, a new Multi-Angle Implementation of Atmospheric Correction (MAIAC) algorithm was developed for MODIS which provides AOD at 1 km resolution. Using MAIAC data, the relationship between MAIAC AOD and PM 2.5 as measured by the EPA ground monitoring stations was investigated at varying spatial scales. Our analysis suggested that the correlation between PM 2.5 and AOD decreased significantly as AOD resolution was degraded. This is so despite the intrinsic mismatch between PM 2.5 ground level measurements and AOD vertically integrated measurements. Furthermore, the fine resolution results indicated spatial variability in particle concentration at a sub-10 km scale. Finally, this spatial variability of AOD within the urban domain was shown to depend on PM 2.5 levels and wind speed. - Highlights: ► The correlation between PM 2.5 and AOD decreases as AOD resolution is degraded. ► High resolution MAIAC AOD 1 km retrieval can be used to investigate within-city PM 2.5 variability. ► Low pollution days exhibit higher spatial variability of AOD and PM 2.5 then moderate pollution days. ► AOD spatial variability within urban area is higher during the lower wind speed conditions. - The correlation between PM 2.5 and AOD decreases as AOD resolution is degraded. The new high-resolution MAIAC AOD retrieval has the potential to capture PM 2.5 variability at the intra-urban scale.

  20. Barn Owl Productivity Response to Variability of Vole Populations.

    Directory of Open Access Journals (Sweden)

    Petr Pavluvčík

    Full Text Available We studied the response of the barn owl annual productivity to the common vole population numbers and variability to test the effects of environmental stochasticity on their life histories. Current theory predicts that temporal environmental variability can affect long-term nonlinear responses (e.g., production of young both positively and negatively, depending on the shape of the relationship between the response and environmental variables. At the level of the Czech Republic, we examined the shape of the relationship between the annual sum of fledglings (annual productivity and vole numbers in both non-detrended and detrended data. At the districts' level, we explored whether the degree of synchrony (measured by the correlation coefficient and the strength of the productivity response increase (measured by the regression coefficient in areas with higher vole population variability measured by the s-index. We found that the owls' annual productivity increased linearly with vole numbers in the Czech Republic. Furthermore, based on district data, we also found that synchrony between dynamics in owls' reproductive output and vole numbers increased with vole population variability. However, the strength of the response was not affected by the vole population variability. Additionally, we have shown that detrending remarkably increases the Taylor's exponent b relating variance to mean in vole time series, thereby reversing the relationship between the coefficient of variation and the mean. This shift was not responsible for the increased synchrony with vole population variability. Instead, we suggest that higher synchrony could result from high food specialization of owls on the common vole in areas with highly fluctuating vole populations.

  1. Gender and Conflict Resolution Strategies in Spanish Teen Couples: Their Relationship With Jealousy and Emotional Dependency.

    Science.gov (United States)

    Perles, Fabiola; San Martín, Jesús; Canto, Jesús M

    2016-06-08

    Previous research has pointed to the need to address the study of violence in teen couples. However, research has not delved into the study of the variables related to the different types of violence employed by boys and girls. The purpose of this study was to test whether gender, jealousy, and dependency predict specific strategies for conflict resolution (psychological aggression and mild physical aggression). Another objective of the study was to test gender differences in the conflict resolution strategies used by Spanish teen couples and to test the association between these variables and jealousy and emotional dependency. A sample of 296 adolescent high school students between 14 and 19 years of age of both genders from the south of Spain participated in this study. Hierarchical regression models were used to estimate the relationship between psychological aggression and mild physical aggression, and jealousy, and dependency. Results showed that jealousy correlated with psychological aggression and mild physical aggression in girls but not in boys. Psychological aggression and mild physical aggression were associated with dependency in boys. Girls scored higher in psychological aggression and jealousy than did boys. Finally, the interaction between jealousy and dependency predicted psychological aggression only in girls. These results highlight the need to address the role of the interaction between dependence and jealousy in the types of violence employed in teen dating. However, it is necessary to delve into the gender differences and similarities to develop appropriate prevention programs. © The Author(s) 2016.

  2. Search for rapid variability of 53 Cam

    International Nuclear Information System (INIS)

    Zverko, J.

    1982-01-01

    Photoelectric observations of magnetic Ap star 53 Cam made at the Skalnate Pleso Observatory in 1978 and 1979 are analyzed from the point of view of rapid variability. The observations were made with an intermediate passband filter, effective wavelength 526 nm. Besides the differences msub(53Cam)-msub(Comp), the behaviour was also investigated of the deflections for the comparison star during the observation runs. A strong correlation between the behaviour of the comparison and variable star light curve was found and the appearance differs from night to night depending on atmospheric conditions. Each observation run is analyzed in detail and it was concluded that all observed variations are only apparent and due to the variability of atmospheric extinction above the observation site. (author)

  3. Ultrasonic variables affecting inspection

    International Nuclear Information System (INIS)

    Lautzenheiser, C.E.; Whiting, A.R.; McElroy, J.T.

    1977-01-01

    There are many variables which affect the detection of the effects and reproducibility of results when utilizing ultrasonic techniques. The most important variable is the procedure, as this document specifies, to a great extent, the controls that are exercised over the other variables. The most important variable is personnel with regards to training, qualification, integrity, data recording, and data analysis. Although the data is very limited, these data indicate that, if the procedure is carefully controlled, reliability of defect detection and reproducibility of results are both approximately 90 percent for reliability of detection, this applies to relatively small defects as reliability increases substantially as defect size increases above the recording limit. (author)

  4. CFD results for temperature dependence water cooling pump NPSH calculations - 15425

    International Nuclear Information System (INIS)

    Strongin, M.P.

    2015-01-01

    In this work the possibility to model the pump for water cooling reactors behavior in the critical situation was considered for cases when water temperature suddenly increases. In cases like this, cavitation effects may cause pump shutoff and consequently stop the reactor cooling. Centrifugal pump was modeled. The calculations demonstrate strong dependence of NPSH (net-positive-suction-head) on the water temperature on the pump inlet. The water temperature on the inlet lies between 25 and 180 C. degrees. The pump head performance curve has a step-like slope below NPSH point. Therefore, if the pressure on the pump inlet is below than NPSH, it leads to the pump shutoff. For high water temperature on the pump inlet, NPSH follows the vapor saturated pressure for given temperature with some offset. The results clearly show that in case of accidental increase of temperature in the cooling loop, special measures are needed to support the pressure on the pump inlet to prevent pump shutoff. (author)

  5. The reliable solution and computation time of variable parameters Logistic model

    OpenAIRE

    Pengfei, Wang; Xinnong, Pan

    2016-01-01

    The reliable computation time (RCT, marked as Tc) when applying a double precision computation of a variable parameters logistic map (VPLM) is studied. First, using the method proposed, the reliable solutions for the logistic map are obtained. Second, for a time-dependent non-stationary parameters VPLM, 10000 samples of reliable experiments are constructed, and the mean Tc is then computed. The results indicate that for each different initial value, the Tcs of the VPLM are generally different...

  6. Body position-dependent shift in odor percept present only for perithreshold odors.

    Science.gov (United States)

    Lundström, Johan N; Boyle, Julie A; Jones-Gotman, Marilyn

    2008-01-01

    We recently demonstrated that a supine position causes a decrease in olfactory sensitivity compared with an upright position. We pursued that initial finding in 3 separate experiments in which we explored the extent of, and mechanism underlying, this phenomenon. In Experiment 1, we replicated the decrease in olfactory sensitivity when in a supine compared with an upright position. In Experiment 2, we measured body position-dependent shifts in physiological variables and sniff measures while smelling suprathreshold odorants and performing a perithreshold odor intensity discrimination task. Olfactory performances were reduced while supine. However, no relationships between the shift in olfactory performances and either the physiological variables or sniff measures were found. In Experiment 3, we determined that there were no position-dependent shifts in ability to discriminate or identify suprathreshold odors or rate them for pleasantness, intensity, or familiarity. However, a drop in scores was observed, and performance was slowed, on a cognitive skill while supine. These results demonstrate a body position-dependent shift in olfactory sensitivity only for perithreshold odors that appears to be mediated by cognitive rather than physiological factors. Implications for olfactory imaging studies are discussed.

  7. Cataclysmic Variable Stars

    Science.gov (United States)

    Hellier, Coel

    2001-01-01

    Cataclysmic variable stars are the most variable stars in the night sky, fluctuating in brightness continually on timescales from seconds to hours to weeks to years. The changes can be recorded using amateur telescopes, yet are also the subject of intensive study by professional astronomers. That study has led to an understanding of cataclysmic variables as binary stars, orbiting so closely that material transfers from one star to the other. The resulting process of accretion is one of the most important in astrophysics. This book presents the first account of cataclysmic variables at an introductory level. Assuming no previous knowledge of the field, it explains the basic principles underlying the variability, while providing an extensive compilation of cataclysmic variable light curves. Aimed at amateur astronomers, undergraduates, and researchers, the main text is accessible to those with no mathematical background, while supplementary boxes present technical details and equations.

  8. Feasibility of Ecological Momentary Assessment Using Cellular Telephones in Methamphetamine Dependent Subjects

    Directory of Open Access Journals (Sweden)

    John Mendelson

    2008-01-01

    Full Text Available Background: Predictors of relapse to methamphetamine use are poorly understood. State variables may play an important role in relapse, but they have been difficult to measure at frequent intervals in outpatients.Methods: We conducted a feasibility study of the use of cellular telephones to collect state variable data from outpatients. Six subjects in treatment for methamphetamine dependence were called three times per weekday for approximately seven weeks. Seven questionnaires were administered that assessed craving, stress, affect and current type of location and social environment.Results: 395/606 (65% of calls attempted were completed. The mean time to complete each call was 4.9 (s.d. 1.8 minutes and the mean time to complete each item was 8.4 (s.d. 4.8 seconds. Subjects rated the acceptability of the procedures as good. All six cellular phones and battery chargers were returned undamaged.Conclusion: Cellular telephones are a feasible method for collecting state data from methamphetamine dependent outpatients.

  9. Bone densitometry in normal women of reproductive age: Correlation with reference values and anthropometric variables

    International Nuclear Information System (INIS)

    Lobo, G.; Palma, T.; Ladron de Guevara, D.

    2002-01-01

    Bone mass density measurements using X rays is considered to be the non-invasive reference method to measure bone mineral density. Even though the technology has reached a high level of development, precision and reproducibility must be optimised to assure that the observed variations are due solely to the variations in bone mineral content, and not to other associated variables, either technical or biological. The main factors affecting bone density measurements are those that depend on the technique used and those which depend on characteristics of the individuals. The variability associated with the technique can be minimised by an adequate standardisation and quality control. Among those characteristics of the individuals, which have been mentioned as a source of variability, the most important are related to the anthropomorphic characteristics such as size and depth of osseous structures, and thickness and characteristics of soft tissues. These factors may be especially important because the interpretation of bone mass density measurements depends on values obtained for reference normal populations, which are incorporated into the bone mass densitometers as reference value databases. Usually the anthropomorphic characteristics of this reference population are unknown and can be different from those of the local population, independently of genetic or ethnic factors. This situation leads to error both in the definition of basic concepts such as osteopenia and osteoporosis, and in the interpretation of individual results for population studies. The purpose of this study is to correlate bone density measurements of normal Chilean women with reference value databases and with parameters, which depend on body size

  10. New results on inclusive and reaction plane dependent dijet asymmetry in Pb+Pb collisions with ATLAS

    CERN Document Server

    Perepelitsa, Dennis; The ATLAS collaboration

    2015-01-01

    The phenomenon of events containing highly asymmetric dijet pairs is one of the most striking results in heavy ion physics. It has provided the first direct observation of in-medium jet energy loss at the LHC. Detailed measurements of centrality-dependent dijet imbalance in $\\sqrt{s_\\mathrm{NN}}$ = 2.76 TeV Pb+Pb collisions using data collected in the 2011 LHC heavy ion run are presented. The new analysis fully corrects to the particle level. The results show a centrality-dependent modification of the dijet asymmetry distribution accompanied by an unmodified angular correlation between two jets in the dijet system. Detailed studies of the dijet asymmetry as a function of the leading jet transverse momentum and jet radius are presented. The reference measurement of the dijet asymmetry in the $pp$ collisions at the same center of mass energy is also shown. The dijet asymmetry measurements are also done while selecting the leading jet at different angles with respect to the second order event-plane. This effecti...

  11. A fast chaos-based image encryption scheme with a dynamic state variables selection mechanism

    Science.gov (United States)

    Chen, Jun-xin; Zhu, Zhi-liang; Fu, Chong; Yu, Hai; Zhang, Li-bo

    2015-03-01

    In recent years, a variety of chaos-based image cryptosystems have been investigated to meet the increasing demand for real-time secure image transmission. Most of them are based on permutation-diffusion architecture, in which permutation and diffusion are two independent procedures with fixed control parameters. This property results in two flaws. (1) At least two chaotic state variables are required for encrypting one plain pixel, in permutation and diffusion stages respectively. Chaotic state variables produced with high computation complexity are not sufficiently used. (2) The key stream solely depends on the secret key, and hence the cryptosystem is vulnerable against known/chosen-plaintext attacks. In this paper, a fast chaos-based image encryption scheme with a dynamic state variables selection mechanism is proposed to enhance the security and promote the efficiency of chaos-based image cryptosystems. Experimental simulations and extensive cryptanalysis have been carried out and the results prove the superior security and high efficiency of the scheme.

  12. Interannual variability of the stratospheric wave driving during northern winter

    Directory of Open Access Journals (Sweden)

    H. M. Kelder

    2007-05-01

    Full Text Available The strength of the stratospheric wave driving during northern winter is often quantified by the January–February mean poleward eddy heat flux at 100 hPa, averaged over 40°–80° N (or a similar area and period. Despite the dynamical and chemical relevance of the wave driving, the causes for its variability are still not well understood. In this study, ERA-40 reanalysis data for the period 1979–2002 are used to examine several factors that significantly affect the interannual variability of the wave driving. The total poleward heat flux at 100 hPa is poorly correlated with that in the troposphere, suggesting a decoupling between 100 hPa and the troposphere. However, the individual zonal wave-1 and wave-2 contributions to the wave driving at 100 hPa do exhibit a significant coupling with the troposphere, predominantly their stationary components. The stationary wave-1 contribution to the total wave driving significantly depends on the latitude of the stationary wave-1 source in the troposphere. The results suggest that this dependence is associated with the varying ability of stationary wave-1 activity to enter the tropospheric waveguide at mid-latitudes. The wave driving anomalies are separated into three parts: one part due to anomalies in the zonal correlation coefficient between the eddy temperature and eddy meridional wind, another part due to anomalies in the zonal eddy temperature amplitude, and a third part due to anomalies in the zonal eddy meridional wind amplitude. It is found that year-to-year variability in the zonal correlation coefficient between the eddy temperature and the eddy meridional wind is the most dominant factor in explaining the year-to-year variability of the poleward eddy heat flux.

  13. Hydration level is an internal variable for computing motivation to obtain water rewards in monkeys.

    Science.gov (United States)

    Minamimoto, Takafumi; Yamada, Hiroshi; Hori, Yukiko; Suhara, Tetsuya

    2012-05-01

    In the process of motivation to engage in a behavior, valuation of the expected outcome is comprised of not only external variables (i.e., incentives) but also internal variables (i.e., drive). However, the exact neural mechanism that integrates these variables for the computation of motivational value remains unclear. Besides, the signal of physiological needs, which serves as the primary internal variable for this computation, remains to be identified. Concerning fluid rewards, the osmolality level, one of the physiological indices for the level of thirst, may be an internal variable for valuation, since an increase in the osmolality level induces drinking behavior. Here, to examine the relationship between osmolality and the motivational value of a water reward, we repeatedly measured the blood osmolality level, while 2 monkeys continuously performed an instrumental task until they spontaneously stopped. We found that, as the total amount of water earned increased, the osmolality level progressively decreased (i.e., the hydration level increased) in an individual-dependent manner. There was a significant negative correlation between the error rate of the task (the proportion of trials with low motivation) and the osmolality level. We also found that the increase in the error rate with reward accumulation can be well explained by a formula describing the changes in the osmolality level. These results provide a biologically supported computational formula for the motivational value of a water reward that depends on the hydration level, enabling us to identify the neural mechanism that integrates internal and external variables.

  14. Using variable combination population analysis for variable selection in multivariate calibration.

    Science.gov (United States)

    Yun, Yong-Huan; Wang, Wei-Ting; Deng, Bai-Chuan; Lai, Guang-Bi; Liu, Xin-bo; Ren, Da-Bing; Liang, Yi-Zeng; Fan, Wei; Xu, Qing-Song

    2015-03-03

    Variable (wavelength or feature) selection techniques have become a critical step for the analysis of datasets with high number of variables and relatively few samples. In this study, a novel variable selection strategy, variable combination population analysis (VCPA), was proposed. This strategy consists of two crucial procedures. First, the exponentially decreasing function (EDF), which is the simple and effective principle of 'survival of the fittest' from Darwin's natural evolution theory, is employed to determine the number of variables to keep and continuously shrink the variable space. Second, in each EDF run, binary matrix sampling (BMS) strategy that gives each variable the same chance to be selected and generates different variable combinations, is used to produce a population of subsets to construct a population of sub-models. Then, model population analysis (MPA) is employed to find the variable subsets with the lower root mean squares error of cross validation (RMSECV). The frequency of each variable appearing in the best 10% sub-models is computed. The higher the frequency is, the more important the variable is. The performance of the proposed procedure was investigated using three real NIR datasets. The results indicate that VCPA is a good variable selection strategy when compared with four high performing variable selection methods: genetic algorithm-partial least squares (GA-PLS), Monte Carlo uninformative variable elimination by PLS (MC-UVE-PLS), competitive adaptive reweighted sampling (CARS) and iteratively retains informative variables (IRIV). The MATLAB source code of VCPA is available for academic research on the website: http://www.mathworks.com/matlabcentral/fileexchange/authors/498750. Copyright © 2015 Elsevier B.V. All rights reserved.

  15. Existence results for impulsive evolution differential equations with state-dependent delay

    OpenAIRE

    Eduardo Hernandez M.; Rathinasamy Sakthivel; Sueli Tanaka Aki

    2008-01-01

    We study the existence of mild solution for impulsive evolution abstract differential equations with state-dependent delay. A concrete application to partial delayed differential equations is considered.

  16. Comparative response of Rangifer tarandus and other northern ungulates to climatic variability

    Directory of Open Access Journals (Sweden)

    Robert B. Weladji

    2002-06-01

    Full Text Available To understand the factors influencing life history traits and population dynamics, attention is increasingly being given to the importance of environmental stochasticity. In this paper, we review and discuss aspects of current knowledge concerning the effect of climatic variation (local and global on population parameters of northern ungu¬lates, with special emphasis on reindeer/caribou (Rangifer tarandus. We also restrict ourselves to indirect effects of climate through both forage availability and quality, and insect activity. Various authors have used different weather variables; with sometime opposite trends in resulting life history traits of ungulates, and few studies show consistent effects to the same climatic variables. There is thus little consensus about which weather variables play the most sig¬nificant role influencing ungulate population parameters. This may be because the effects of weather on ungulate pop¬ulation dynamics and life history traits are scale dependent and it is difficult to isolate climatic effects from density dependent factors. This confirms the complexity of the relationship between environment and ecosystem. We point out limits of comparability between systems and the difficulty of generalizing about the effect of climate change broadly across northern systems, across species and even within species. Furthermore, insect harassment appears to be a key climate-related factor for the ecology of reindeer/caribou that has been overlooked in the literature of climatic effects on large herbivores. In light of this, there is a need for further studies of long time series in assessing effects of climate variability on reindeer/caribou.

  17. Non-Dependent and Dependent Daily Cannabis Users Differ in Mental Health but Not Prospective Memory Ability

    Directory of Open Access Journals (Sweden)

    Ruth Braidwood

    2018-03-01

    Full Text Available Research suggests that daily cannabis users have impaired memory for past events, but it is not clear whether they are also impaired in prospective memory (PM for future events. The present study examined PM in daily cannabis users who were either dependent (n = 18 or non-dependent (n = 18, and compared them with non-using controls (n = 18. The effect of future event simulation (FES on PM performance was also examined. Participants were matched across groups on age, gender, and highest level of education. The virtual week (VW was used to objectively assess PM abilities, both at baseline and following FES. Other measures used were: cannabis use variables, immediate and delayed prose recall, phonemic and category fluency, spot-the-word test (premorbid intelligence, Beck Depression Inventory, Beck Anxiety Inventory, and a measure of schizotypy (Oxford-Liverpool Inventory of Feelings and Experiences: unusual experiences subscale. No group differences were found in PM performance on the VW, and FES did not improve PM performance in any group. Dependent cannabis users scored higher on depression, anxiety, and schizotypy than both other groups with non-dependent cannabis users scoring at a similar level to controls. There were no group differences in alcohol use. Findings suggest that when carefully matched on baseline variables, and not differing in premorbid IQ or alcohol use, young, near-daily cannabis users do not differ from non-using controls in PM performance.

  18. Influence of process variables on permeability and anisotropy of Biso-coated HTGR fuel particles

    International Nuclear Information System (INIS)

    Stinton, D.P.; Lackey, W.J.; Thiele, B.A.

    1977-11-01

    The effect of several important process variables on the fraction of defective particles and anisotropy of the low-temperature isotropic (LTI) coating layer was determined for Biso-coated HTGR fuel particles. Process variables considered are deposition temperature, hydrocarbon type, diluent type, and percent diluent. The effect of several other variables such as coating rate and density that depend on the process variables were also considered in this analysis. The fraction of defective particles was controlled by the dependent variables coating rate and LTI density. Coating rate was also the variable controlling the anisotropy of the LTI layer. Diluent type and diluent concentration had only a small influence on the deposition rate of the LTI layer. High-quality particles in terms of anisotropy and permeability can be produced by use of a porous plate gas distributor if the coating rate is between 3 and 5 μm/min and the coating density is between about 1.75 and 1.95 g/cm 3

  19. Spatial and temporal variability of interhemispheric transport times

    Science.gov (United States)

    Wu, Xiaokang; Yang, Huang; Waugh, Darryn W.; Orbe, Clara; Tilmes, Simone; Lamarque, Jean-Francois

    2018-05-01

    The seasonal and interannual variability of transport times from the northern midlatitude surface into the Southern Hemisphere is examined using simulations of three idealized age tracers: an ideal age tracer that yields the mean transit time from northern midlatitudes and two tracers with uniform 50- and 5-day decay. For all tracers the largest seasonal and interannual variability occurs near the surface within the tropics and is generally closely coupled to movement of the Intertropical Convergence Zone (ITCZ). There are, however, notable differences in variability between the different tracers. The largest seasonal and interannual variability in the mean age is generally confined to latitudes spanning the ITCZ, with very weak variability in the southern extratropics. In contrast, for tracers subject to spatially uniform exponential loss the peak variability tends to be south of the ITCZ, and there is a smaller contrast between tropical and extratropical variability. These differences in variability occur because the distribution of transit times from northern midlatitudes is very broad and tracers with more rapid loss are more sensitive to changes in fast transit times than the mean age tracer. These simulations suggest that the seasonal-interannual variability in the southern extratropics of trace gases with predominantly NH midlatitude sources may differ depending on the gases' chemical lifetimes.

  20. Fire-regime variability impacts forest carbon dynamics for centuries to millennia

    Science.gov (United States)

    Hudiburg, Tara W.; Higuera, Philip E.; Hicke, Jeffrey A.

    2017-08-01

    Wildfire is a dominant disturbance agent in forest ecosystems, shaping important biogeochemical processes including net carbon (C) balance. Long-term monitoring and chronosequence studies highlight a resilience of biogeochemical properties to large, stand-replacing, high-severity fire events. In contrast, the consequences of repeated fires or temporal variability in a fire regime (e.g., the characteristic timing or severity of fire) are largely unknown, yet theory suggests that such variability could strongly influence forest C trajectories (i.e., future states or directions) for millennia. Here we combine a 4500-year paleoecological record of fire activity with ecosystem modeling to investigate how fire-regime variability impacts soil C and net ecosystem carbon balance. We found that C trajectories in a paleo-informed scenario differed significantly from an equilibrium scenario (with a constant fire return interval), largely due to variability in the timing and severity of past fires. Paleo-informed scenarios contained multi-century periods of positive and negative net ecosystem C balance, with magnitudes significantly larger than observed under the equilibrium scenario. Further, this variability created legacies in soil C trajectories that lasted for millennia. Our results imply that fire-regime variability is a major driver of C trajectories in stand-replacing fire regimes. Predicting carbon balance in these systems, therefore, will depend strongly on the ability of ecosystem models to represent a realistic range of fire-regime variability over the past several centuries to millennia.

  1. IRAS variables as galactic structure tracers - Classification of the bright variables

    Science.gov (United States)

    Allen, L. E.; Kleinmann, S. G.; Weinberg, M. D.

    1993-01-01

    The characteristics of the 'bright infrared variables' (BIRVs), a sample consisting of the 300 brightest stars in the IRAS Point Source Catalog with IRAS variability index VAR of 98 or greater, are investigated with the purpose of establishing which of IRAS variables are AGB stars (e.g., oxygen-rich Miras and carbon stars, as was assumed by Weinberg (1992)). Results of the analysis of optical, infrared, and microwave spectroscopy of these stars indicate that, out of 88 stars in the BIRV sample identified with cataloged variables, 86 can be classified as Miras. Results of a similar analysis performed for a color-selected sample of stars, using the color limits employed by Habing (1988) to select AGB stars, showed that, out of 52 percent of classified stars, 38 percent are non-AGB stars, including H II regions, planetary nebulae, supergiants, and young stellar objects, indicating that studies using color-selected samples are subject to misinterpretation.

  2. Climate variability, communities’ perceptions and land management strategies in Lay Gayint Woreda, Northwest Ethiopia

    Directory of Open Access Journals (Sweden)

    Menberu Teshome

    2018-04-01

    Full Text Available Climate variability is the fluctuation of climatic elements from the normal or baseline values. Agrarian communities are the most sensitive social groups to climate variability and associate extreme weather-induced hazards due to the fact that climate variability affects the two most important direct agricultural production inputs, such as rainfall and temperature. As Ethiopia is heavily dependent on agriculture its economic development is being hindered by climate variability coupled with many other deriving forces. Therefore, the objective of this study is to examine climate variability, local communities’ perceptions and land management strategies to reduce the adverse impact of climate variability in Lay Gayint Woreda, Ethiopia. Both primary and secondary data were used to complete this study. Primary data were collected and analyzed from a total of 200 randomly selected respondents reside in different agro-ecological areas. Metrology data were gathered from Nefas Mewcha Station from the years 1979 to 2010. Standardized rainfall anomaly index (SRAI, crop diversification index (CDI and other descriptive statistical techniques were used to analyze the data. The results obtained from the climate data revealed an increase in temperature, and decrease and/or erratic in rainfall distribution. Time series SRAI from 1979 to 2010 indicates that 2002 and 2008 were characterized by extreme and severe dry conditions in order of importance with high impact on crop yields whist only 1984 and 1990 received near normal rainfall amount. Similarly, the survey result reveals that out of the total household heads, 87.5 % perceived that there was an increase in temperature over the last 20 years. The survey result also disclosed that significant numbers of households are more likely to adopt different land management strategies to reduce the negative impact of climate variability. Constructing terraces and check dams as well as planting trees were the major

  3. Life-cycle studies of biodiesel in Europe: A review addressing the variability of results and modeling issues

    International Nuclear Information System (INIS)

    Malca, Joao; Freire, Fausto

    2011-01-01

    Renewable energy sources, and particularly biofuels, are being promoted as possible solutions to address global warming and the depletion of petroleum resources. Nevertheless, significant disagreement and controversies exist regarding the actual benefits of biofuels displacing fossil fuels, as shown by a large number of life-cycle studies that have varying and sometimes contradictory conclusions. This article presents a comprehensive review of life-cycle studies of biodiesel in Europe. Studies have been compared in terms of nonrenewable primary energy requirement and GHG intensity of biodiesel. Recently published studies negate the definite and deterministic advantages for biodiesel presented in former studies. A high variability of results, particularly for biodiesel GHG intensity, with emissions ranging from 15 to 170 gCO 2 eq MJ f -1 has been observed. A detailed assessment of relevant aspects, including major assumptions, modeling choices and results, has been performed. The main causes for this high variability have been investigated, with emphasis on modeling choices. Key issues found are treatment of co-product and land use modeling, including high uncertainty associated with N 2 O and carbon emissions from cultivated soil. Furthermore, a direct correlation between how soil emissions were modeled and increasing values for calculated GHG emission has been found. A robust biodiesel life-cycle modeling has been implemented and the main sources of uncertainty have been investigated to show how uncertainty can be addressed to improve the transparency and reliability of results. Recommendations for further research work concerning the improvement of biofuel life cycle modeling are also presented. (author)

  4. Results of a comparative study on insulin radioimmunoassay in 36 Italian laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Costantini, A; Lostia, O; Malvano, R; Rolleri, E; Taggi, F; Zucchelli, G C [Istituto Superiore di Sanita, Rome (Italy); Consiglio Nazionale delle Ricerche, Pisa (Italy))

    1975-12-01

    An interlaboratory study in which the insulin contents of five plasma samples were estimated in 36 italian laboratories was coordinated by the Istituto Superiore di Sanita (National Institute of Health) and the Consiglio Nazionale delle Ricerche (National Research Council). A rather large between-laboratory variability resulted, though the ranking of samples according to their insulin concentrations was practically the same. A significant dependence of estimates on the method used was established. The analysis of data aimed at defining the possible reasons of the assay variability is reported and discussed.

  5. Variable recruitment fluidic artificial muscles: modeling and experiments

    International Nuclear Information System (INIS)

    Bryant, Matthew; Meller, Michael A; Garcia, Ephrahim

    2014-01-01

    We investigate taking advantage of the lightweight, compliant nature of fluidic artificial muscles to create variable recruitment actuators in the form of artificial muscle bundles. Several actuator elements at different diameter scales are packaged to act as a single actuator device. The actuator elements of the bundle can be connected to the fluidic control circuit so that different groups of actuator elements, much like individual muscle fibers, can be activated independently depending on the required force output and motion. This novel actuation concept allows us to save energy by effectively impedance matching the active size of the actuators on the fly based on the instantaneous required load. This design also allows a single bundled actuator to operate in substantially different force regimes, which could be valuable for robots that need to perform a wide variety of tasks and interact safely with humans. This paper proposes, models and analyzes the actuation efficiency of this actuator concept. The analysis shows that variable recruitment operation can create an actuator that reduces throttling valve losses to operate more efficiently over a broader range of its force–strain operating space. We also present preliminary results of the design, fabrication and experimental characterization of three such bioinspired variable recruitment actuator prototypes. (paper)

  6. Variability and trends in the Arctic Sea ice cover: Results from different techniques

    Science.gov (United States)

    Comiso, Josefino C.; Meier, Walter N.; Gersten, Robert

    2017-08-01

    Variability and trend studies of sea ice in the Arctic have been conducted using products derived from the same raw passive microwave data but by different groups using different algorithms. This study provides consistency assessment of four of the leading products, namely, Goddard Bootstrap (SB2), Goddard NASA Team (NT1), EUMETSAT Ocean and Sea Ice Satellite Application Facility (OSI-SAF 1.2), and Hadley HadISST 2.2 data in evaluating variability and trends in the Arctic sea ice cover. All four provide generally similar ice patterns but significant disagreements in ice concentration distributions especially in the marginal ice zone and adjacent regions in winter and meltponded areas in summer. The discrepancies are primarily due to different ways the four techniques account for occurrences of new ice and meltponding. However, results show that the different products generally provide consistent and similar representation of the state of the Arctic sea ice cover. Hadley and NT1 data usually provide the highest and lowest monthly ice extents, respectively. The Hadley data also show the lowest trends in ice extent and ice area at -3.88%/decade and -4.37%/decade, respectively, compared to an average of -4.36%/decade and -4.57%/decade for all four. Trend maps also show similar spatial distribution for all four with the largest negative trends occurring at the Kara/Barents Sea and Beaufort Sea regions, where sea ice has been retreating the fastest. The good agreement of the trends especially with updated data provides strong confidence in the quantification of the rate of decline in the Arctic sea ice cover.Plain Language SummaryThe declining Arctic sea ice cover, especially in the summer, has been the center of attention in recent years. Reports on the sea ice cover have been provided by different institutions using basically the same set of satellite data but different techniques for estimating key parameters such as ice concentration, ice extent, and ice area. In

  7. Variable dead time counters: 2. A computer simulation

    International Nuclear Information System (INIS)

    Hooton, B.W.; Lees, E.W.

    1980-09-01

    A computer model has been developed to give a pulse train which simulates that generated by a variable dead time counter (VDC) used in safeguards determination of Pu mass. The model is applied to two algorithms generally used for VDC analysis. It is used to determine their limitations at high counting rates and to investigate the effects of random neutrons from (α,n) reactions. Both algorithms are found to be deficient for use with masses of 240 Pu greater than 100g and one commonly used algorithm is shown, by use of the model and also by theory, to yield a result which is dependent on the random neutron intensity. (author)

  8. Self-produced Time Intervals Are Perceived as More Variable and/or Shorter Depending on Temporal Context in Subsecond and Suprasecond Ranges

    Directory of Open Access Journals (Sweden)

    Keita eMitani

    2016-06-01

    Full Text Available The processing of time intervals is fundamental for sensorimotor and cognitive functions. Perceptual and motor timing are often performed concurrently (e.g., playing a musical instrument. Although previous studies have shown the influence of body movements on time perception, how we perceive self-produced time intervals has remained unclear. Furthermore, it has been suggested that the timing mechanisms are distinct for the sub- and suprasecond ranges. Here, we compared perceptual performances for self-produced and passively presented time intervals in random contexts (i.e., multiple target intervals presented in a session across the sub- and suprasecond ranges (Experiment 1 and within the sub- (Experiment 2 and suprasecond (Experiment 3 ranges, and in a constant context (i.e., a single target interval presented in a session in the sub- and suprasecond ranges (Experiment 4. We show that self-produced time intervals were perceived as shorter and more variable across the sub- and suprasecond ranges and within the suprasecond range but not within the subsecond range in a random context. In a constant context, the self-produced time intervals were perceived as more variable in the suprasecond range but not in the subsecond range. The impairing effects indicate that motor timing interferes with perceptual timing. The dependence of impairment on temporal contexts suggests multiple timing mechanisms for the subsecond and suprasecond ranges. In addition, violation of the scalar property (i.e., a constant variability to target interval ratio was observed between the sub- and suprasecond ranges. The violation was clearer for motor timing than for perceptual timing. This suggests that the multiple timing mechanisms for the sub- and suprasecond ranges overlap more for perception than for motor. Moreover, the central tendency effect (i.e., where shorter base intervals are overestimated and longer base intervals are underestimated disappeared with subsecond

  9. Numerical studies of time-independent and time-dependent scattering by several elliptical cylinders

    Science.gov (United States)

    Nigsch, Martin

    2007-07-01

    A numerical solution to the problem of time-dependent scattering by an array of elliptical cylinders with parallel axes is presented. The solution is an exact one, based on the separation-of-variables technique in the elliptical coordinate system, the addition theorem for Mathieu functions, and numerical integration. Time-independent solutions are described by a system of linear equations of infinite order which are truncated for numerical computations. Time-dependent solutions are obtained by numerical integration involving a large number of these solutions. First results of a software package generating these solutions are presented: wave propagation around three impenetrable elliptical scatterers. As far as we know, this method described has never been used for time-dependent multiple scattering.

  10. Some results on convergence rates for probabilities of moderate deviations for sums of random variables

    Directory of Open Access Journals (Sweden)

    Deli Li

    1992-01-01

    Full Text Available Let X, Xn, n≥1 be a sequence of iid real random variables, and Sn=∑k=1nXk, n≥1. Convergence rates of moderate deviations are derived, i.e., the rate of convergence to zero of certain tail probabilities of the partial sums are determined. For example, we obtain equivalent conditions for the convergence of series ∑n≥1(ψ2(n/nP(|Sn|≥nφ(n only under the assumptions convergence that EX=0 and EX2=1, where φ and ψ are taken from a broad class of functions. These results generalize and improve some recent results of Li (1991 and Gafurov (1982 and some previous work of Davis (1968. For b∈[0,1] and ϵ>0, letλϵ,b=∑n≥3((loglognb/nI(|Sn|≥(2+ϵnloglogn.The behaviour of Eλϵ,b as ϵ↓0 is also studied.

  11. A liquid lens switching-based motionless variable fiber-optic delay line

    Science.gov (United States)

    Khwaja, Tariq Shamim; Reza, Syed Azer; Sheikh, Mumtaz

    2018-05-01

    We present a Variable Fiber-Optic Delay Line (VFODL) module capable of imparting long variable delays by switching an input optical/RF signal between Single Mode Fiber (SMF) patch cords of different lengths through a pair of Electronically Controlled Tunable Lenses (ECTLs) resulting in a polarization-independent operation. Depending on intended application, the lengths of the SMFs can be chosen accordingly to achieve the desired VFODL operation dynamic range. If so desired, the state of the input signal polarization can be preserved with the use of commercially available polarization-independent ECTLs along with polarization-maintaining SMFs (PM-SMFs), resulting in an output polarization that is identical to the input. An ECTL-based design also improves power consumption and repeatability. The delay switching mechanism is electronically-controlled, involves no bulk moving parts, and can be fully-automated. The VFODL module is compact due to the use of small optical components and SMFs that can be packaged compactly.

  12. SABER Observations of the OH Meinel Airglow Variability Near the Mesopause

    Science.gov (United States)

    Marsh, Daniel R.; Smith, Anne K.; Mlynczak, Martin G.

    2005-01-01

    The Sounding of the Atmosphere using Broadband Emission Radiometry (SABER) instrument, one of four on board the TIMED satellite, observes the OH Meinel emission at 2.0 m that peaks near the mesopause. The emission results from reactions between members of the oxygen and hydrogen chemical families that can be significantly affected by mesopause dynamics. In this study we compare SABER measurements of OH Meinel emission rates and temperatures with predictions from a 3-dimensional chemical dynamical model. In general, the model is capable of reproducing both the observed diurnal and seasonal OH Meinel emission variability. The results indicate that the diurnal tide has a large effect on the overall magnitude and temporal variation of the emission in low latitudes. This tidal variability is so dominant that the seasonal cycle in the nighttime emission depends very strongly on the local time of the analysis. At higher latitudes, the emission has an annual cycle that is due mainly to transport of oxygen by the seasonally reversing mean circulation.

  13. Some Results on facets for linear inequality in 0-1 variables

    Directory of Open Access Journals (Sweden)

    D. Sashi Bhusan

    2010-03-01

    Full Text Available The facet of Knapsack ploytope, i.e. convex hull of 0-1 points satisfying a given linear inequality has been presented in this current paper. Such type of facets plays an important role in set covering set partitioning, matroidal-intersection vertex- packing, generalized assignment and other combinatorial problems. Strong covers for facets of Knapsack ploytope has been developed in the first part of the present paper. Generating family of valid cutting planes that satisfy inequality with 0-1 variables through algorithms are the attraction of this paper.

  14. Global exponential stability for discrete-time neural networks with variable delays

    International Nuclear Information System (INIS)

    Chen Wuhua; Lu Xiaomei; Liang Dongying

    2006-01-01

    This Letter provides new exponential stability criteria for discrete-time neural networks with variable delays. The main technique is to reduce exponential convergence estimation of the neural network solution to that of one component of the corresponding solution by constructing Lyapunov function based on M-matrix. By introducing the tuning parameter diagonal matrix, the delay-independent and delay-dependent exponential stability conditions have been unified in the same mathematical formula. The effectiveness of the new results are illustrated by three examples

  15. AUTOMATIC CLASSIFICATION OF VARIABLE STARS IN CATALOGS WITH MISSING DATA

    International Nuclear Information System (INIS)

    Pichara, Karim; Protopapas, Pavlos

    2013-01-01

    We present an automatic classification method for astronomical catalogs with missing data. We use Bayesian networks and a probabilistic graphical model that allows us to perform inference to predict missing values given observed data and dependency relationships between variables. To learn a Bayesian network from incomplete data, we use an iterative algorithm that utilizes sampling methods and expectation maximization to estimate the distributions and probabilistic dependencies of variables from data with missing values. To test our model, we use three catalogs with missing data (SAGE, Two Micron All Sky Survey, and UBVI) and one complete catalog (MACHO). We examine how classification accuracy changes when information from missing data catalogs is included, how our method compares to traditional missing data approaches, and at what computational cost. Integrating these catalogs with missing data, we find that classification of variable objects improves by a few percent and by 15% for quasar detection while keeping the computational cost the same

  16. AUTOMATIC CLASSIFICATION OF VARIABLE STARS IN CATALOGS WITH MISSING DATA

    Energy Technology Data Exchange (ETDEWEB)

    Pichara, Karim [Computer Science Department, Pontificia Universidad Católica de Chile, Santiago (Chile); Protopapas, Pavlos [Institute for Applied Computational Science, Harvard University, Cambridge, MA (United States)

    2013-11-10

    We present an automatic classification method for astronomical catalogs with missing data. We use Bayesian networks and a probabilistic graphical model that allows us to perform inference to predict missing values given observed data and dependency relationships between variables. To learn a Bayesian network from incomplete data, we use an iterative algorithm that utilizes sampling methods and expectation maximization to estimate the distributions and probabilistic dependencies of variables from data with missing values. To test our model, we use three catalogs with missing data (SAGE, Two Micron All Sky Survey, and UBVI) and one complete catalog (MACHO). We examine how classification accuracy changes when information from missing data catalogs is included, how our method compares to traditional missing data approaches, and at what computational cost. Integrating these catalogs with missing data, we find that classification of variable objects improves by a few percent and by 15% for quasar detection while keeping the computational cost the same.

  17. Propagation in a waveguide with range-dependent seabed properties.

    Science.gov (United States)

    Holland, Charles W

    2010-11-01

    The ocean environment contains features affecting acoustic propagation that vary on a wide range of time and space scales. A significant body of work over recent decades has aimed at understanding the effects of water column spatial and temporal variability on acoustic propagation. Much less is understood about the impact of spatial variability of seabed properties on propagation, which is the focus of this study. Here, a simple, intuitive expression for propagation with range-dependent boundary properties and uniform water depth is derived. It is shown that incoherent range-dependent propagation depends upon the geometric mean of the seabed plane-wave reflection coefficient and the arithmetic mean of the cycle distance. Thus, only the spatial probability distributions (pdfs) of the sediment properties are required. Also, it is shown that the propagation over a range-dependent seabed tends to be controlled by the lossiest, not the hardest, sediments. Thus, range-dependence generally leads to higher propagation loss than would be expected, due for example to lossy sediment patches and/or nulls in the reflection coefficient. In a few instances, propagation over a range-dependent seabed can be calculated using range-independent sediment properties. The theory may be useful for other (non-oceanic) waveguides.

  18. The Effect Of Omitted Spatial Effects And Social Dependence In The Modelling Of Household Expenditure For Fruits And Vegetables

    Directory of Open Access Journals (Sweden)

    Łaszkiewicz Edyta

    2014-12-01

    Full Text Available As is well known, ignoring spatial heterogeneity leads to biased parameter estimates, while omitting the spatial lag of a dependent variable results in biasness and inconsistency (Anselin, 1988. However, the common approach to analysing households’ expenditures is to ignore the potential spatial effects and social dependence. In light of this, the aim of this paper is to examine the consequences of omitting the spatial effects as well as social dependence in households’ expenditures.

  19. Dependence of nuclear moments of inertia on the triaxial parameter

    International Nuclear Information System (INIS)

    Helgesson, J.; Hamamoto, Ikuko

    1989-01-01

    The dependence of nuclear moments of inertia on the triaxial parameter (γ-variable) is investigated including both the Belyaev term and the Migdal term. The obtained dependence is compared with that of hydrodynamical moments of inertia and other moments of inertia used conventionally. (orig.)

  20. Time-dependent reliability sensitivity analysis of motion mechanisms

    International Nuclear Information System (INIS)

    Wei, Pengfei; Song, Jingwen; Lu, Zhenzhou; Yue, Zhufeng

    2016-01-01

    Reliability sensitivity analysis aims at identifying the source of structure/mechanism failure, and quantifying the effects of each random source or their distribution parameters on failure probability or reliability. In this paper, the time-dependent parametric reliability sensitivity (PRS) analysis as well as the global reliability sensitivity (GRS) analysis is introduced for the motion mechanisms. The PRS indices are defined as the partial derivatives of the time-dependent reliability w.r.t. the distribution parameters of each random input variable, and they quantify the effect of the small change of each distribution parameter on the time-dependent reliability. The GRS indices are defined for quantifying the individual, interaction and total contributions of the uncertainty in each random input variable to the time-dependent reliability. The envelope function method combined with the first order approximation of the motion error function is introduced for efficiently estimating the time-dependent PRS and GRS indices. Both the time-dependent PRS and GRS analysis techniques can be especially useful for reliability-based design. This significance of the proposed methods as well as the effectiveness of the envelope function method for estimating the time-dependent PRS and GRS indices are demonstrated with a four-bar mechanism and a car rack-and-pinion steering linkage. - Highlights: • Time-dependent parametric reliability sensitivity analysis is presented. • Time-dependent global reliability sensitivity analysis is presented for mechanisms. • The proposed method is especially useful for enhancing the kinematic reliability. • An envelope method is introduced for efficiently implementing the proposed methods. • The proposed method is demonstrated by two real planar mechanisms.

  1. Mass dispersions in a time-dependent mean-field approach

    International Nuclear Information System (INIS)

    Balian, R.; Bonche, P.; Flocard, H.; Veneroni, M.

    1984-05-01

    Characteristic functions for single-particle (s.p.) observables are evaluated by means of a time-dependent variational principle, which involves a state and an observable as conjugate variables. This provides a mean-field expression for fluctuations of s.p. observables, such as mass dispersions. The result differs from TDHF, it requires only the use of existing codes, and it presents attractive theoretical features. First numerical tests are encouraging. In particular, a calculation for 16 O + 16 O provides a significant increase of the predicted mass dispersion

  2. Projectile rapidity dependence in target fragmentation

    International Nuclear Information System (INIS)

    Haustein, P.E.; Cumming, J.B.; Hseuh, H.C.

    1979-01-01

    The thick-target, thick-catcher technique was used to determine mean kinetic properties of selected products of the fragmentation of Cu by 1 H, 4 He, and 12 C ions (180 to 28,000 MeV/amu). Momentum transfer, as inferred from F/B ratios, is ovserved to occur most efficiently for the lower velocity projectiles. Recoil properties of target fragments vary strongly with product mass, but show only a weak dependence on projectile type. The projectile's rapidity is shown to be a useful variable for quantitative intercomparison of different reactions. These results indicate that E/sub proj//A/sub proj/ is the dominant parameter which governs the mean recoil behavior of target fragments. 20 references

  3. Analysis of Student and School Level Variables Related to Mathematics Self-Efficacy Level Based on PISA 2012 Results for China-Shanghai, Turkey, and Greece

    Science.gov (United States)

    Usta, H. Gonca

    2016-01-01

    This study aims to analyze the student and school level variables that affect students' self-efficacy levels in mathematics in China-Shanghai, Turkey, and Greece based on PISA 2012 results. In line with this purpose, the hierarchical linear regression model (HLM) was employed. The interschool variability is estimated at approximately 17% in…

  4. Conspicuous plumage colours are highly variable.

    Science.gov (United States)

    Delhey, Kaspar; Szecsenyi, Beatrice; Nakagawa, Shinichi; Peters, Anne

    2017-01-25

    Elaborate ornamental traits are often under directional selection for greater elaboration, which in theory should deplete underlying genetic variation. Despite this, many ornamental traits appear to remain highly variable and how this essential variation is maintained is a key question in evolutionary biology. One way to address this question is to compare differences in intraspecific variability across different types of traits to determine whether high levels of variation are associated with specific trait characteristics. Here we assess intraspecific variation in more than 100 plumage colours across 55 bird species to test whether colour variability is linked to their level of elaboration (indicated by degree of sexual dichromatism and conspicuousness) or their condition dependence (indicated by mechanism of colour production). Conspicuous colours had the highest levels of variation and conspicuousness was the strongest predictor of variability, with high explanatory power. After accounting for this, there were no significant effects of sexual dichromatism or mechanisms of colour production. Conspicuous colours may entail higher production costs or may be more sensitive to disruptions during production. Alternatively, high variability could also be related to increased perceptual difficulties inherent to discriminating highly elaborate colours. Such psychophysical effects may constrain the exaggeration of animal colours. © 2017 The Author(s).

  5. Variables that Predict Serve Efficacy in Elite Men’s Volleyball with Different Quality of Opposition Sets

    Science.gov (United States)

    Valhondo, Álvaro; Fernández-Echeverría, Carmen; González-Silva, Jara; Claver, Fernando; Moreno, M. Perla

    2018-01-01

    Abstract The objective of this study was to determine the variables that predicted serve efficacy in elite men’s volleyball, in sets with different quality of opposition. 3292 serve actions were analysed, of which 2254 were carried out in high quality of opposition sets and 1038 actions were in low quality of opposition sets, corresponding to a total of 24 matches played during the Men’s European Volleyball Championships held in 2011. The independent variables considered in this study were the serve zone, serve type, serving player, serve direction, reception zone, receiving player and reception type; the dependent variable was serve efficacy and the situational variable was quality of opposition sets. The variables that acted as predictors in both high and low quality of opposition sets were the serving player, reception zone and reception type. The serve type variable only acted as a predictor in high quality of opposition sets, while the serve zone variable only acted as a predictor in low quality of opposition sets. These results may provide important guidance in men’s volleyball training processes. PMID:29599869

  6. Discrete-time bidirectional associative memory neural networks with variable delays

    International Nuclear Information System (INIS)

    Liang Jinling; Cao Jinde; Ho, Daniel W.C.

    2005-01-01

    Based on the linear matrix inequality (LMI), some sufficient conditions are presented in this Letter for the existence, uniqueness and global exponential stability of the equilibrium point of discrete-time bidirectional associative memory (BAM) neural networks with variable delays. Some of the stability criteria obtained in this Letter are delay-dependent, and some of them are delay-independent, they are less conservative than the ones reported so far in the literature. Furthermore, the results provide one more set of easily verified criteria for determining the exponential stability of discrete-time BAM neural networks

  7. Discrete-time bidirectional associative memory neural networks with variable delays

    Science.gov (United States)

    Liang, variable delays [rapid communication] J.; Cao, J.; Ho, D. W. C.

    2005-02-01

    Based on the linear matrix inequality (LMI), some sufficient conditions are presented in this Letter for the existence, uniqueness and global exponential stability of the equilibrium point of discrete-time bidirectional associative memory (BAM) neural networks with variable delays. Some of the stability criteria obtained in this Letter are delay-dependent, and some of them are delay-independent, they are less conservative than the ones reported so far in the literature. Furthermore, the results provide one more set of easily verified criteria for determining the exponential stability of discrete-time BAM neural networks.

  8. A Composite Likelihood Inference in Latent Variable Models for Ordinal Longitudinal Responses

    Science.gov (United States)

    Vasdekis, Vassilis G. S.; Cagnone, Silvia; Moustaki, Irini

    2012-01-01

    The paper proposes a composite likelihood estimation approach that uses bivariate instead of multivariate marginal probabilities for ordinal longitudinal responses using a latent variable model. The model considers time-dependent latent variables and item-specific random effects to be accountable for the interdependencies of the multivariate…

  9. The MASIV Survey - IV. Relationship between intra-day scintillation and intrinsic variability of radio AGNs

    Science.gov (United States)

    Koay, J. Y.; Macquart, J.-P.; Jauncey, D. L.; Pursimo, T.; Giroletti, M.; Bignall, H. E.; Lovell, J. E. J.; Rickett, B. J.; Kedziora-Chudczer, L.; Ojha, R.; Reynolds, C.

    2018-03-01

    We investigate the relationship between 5 GHz interstellar scintillation (ISS) and 15 GHz intrinsic variability of compact, radio-selected active galactic nuclei (AGNs) drawn from the Microarcsecond Scintillation-Induced Variability (MASIV) Survey and the Owens Valley Radio Observatory blazar monitoring program. We discover that the strongest scintillators at 5 GHz (modulation index, m5 ≥ 0.02) all exhibit strong 15 GHz intrinsic variability (m15 ≥ 0.1). This relationship can be attributed mainly to the mutual dependence of intrinsic variability and ISS amplitudes on radio core compactness at ˜ 100 μas scales, and to a lesser extent, on their mutual dependences on source flux density, arcsec-scale core dominance and redshift. However, not all sources displaying strong intrinsic variations show high amplitude scintillation, since ISS is also strongly dependent on Galactic line-of-sight scattering properties. This observed relationship between intrinsic variability and ISS highlights the importance of optimizing the observing frequency, cadence, timespan and sky coverage of future radio variability surveys, such that these two effects can be better distinguished to study the underlying physics. For the full MASIV sample, we find that Fermi-detected gamma-ray loud sources exhibit significantly higher 5 GHz ISS amplitudes than gamma-ray quiet sources. This relationship is weaker than the known correlation between gamma-ray loudness and the 15 GHz variability amplitudes, most likely due to jet opacity effects.

  10. The influence of climate variables on dengue in Singapore.

    Science.gov (United States)

    Pinto, Edna; Coelho, Micheline; Oliver, Leuda; Massad, Eduardo

    2011-12-01

    In this work we correlated dengue cases with climatic variables for the city of Singapore. This was done through a Poisson Regression Model (PRM) that considers dengue cases as the dependent variable and the climatic variables (rainfall, maximum and minimum temperature and relative humidity) as independent variables. We also used Principal Components Analysis (PCA) to choose the variables that influence in the increase of the number of dengue cases in Singapore, where PC₁ (Principal component 1) is represented by temperature and rainfall and PC₂ (Principal component 2) is represented by relative humidity. We calculated the probability of occurrence of new cases of dengue and the relative risk of occurrence of dengue cases influenced by climatic variable. The months from July to September showed the highest probabilities of the occurrence of new cases of the disease throughout the year. This was based on an analysis of time series of maximum and minimum temperature. An interesting result was that for every 2-10°C of variation of the maximum temperature, there was an average increase of 22.2-184.6% in the number of dengue cases. For the minimum temperature, we observed that for the same variation, there was an average increase of 26.1-230.3% in the number of the dengue cases from April to August. The precipitation and the relative humidity, after analysis of correlation, were discarded in the use of Poisson Regression Model because they did not present good correlation with the dengue cases. Additionally, the relative risk of the occurrence of the cases of the disease under the influence of the variation of temperature was from 1.2-2.8 for maximum temperature and increased from 1.3-3.3 for minimum temperature. Therefore, the variable temperature (maximum and minimum) was the best predictor for the increased number of dengue cases in Singapore.

  11. Dark focus of accommodation as dependent and independent variables in visual display technology

    Science.gov (United States)

    Jones, Sherrie; Kennedy, Robert; Harm, Deborah

    1992-01-01

    When independent stimuli are available for accommodation, as in the dark or under low contrast conditions, the lens seeks its resting position. Individual differences in resting positions are reliable, under autonomic control, and can change with visual task demands. We hypothesized that motion sickness in a flight simulator might result in dark focus changes. Method: Subjects received training flights in three different Navy flight simulators. Two were helicopter simulators entailed CRT presentation using infinity optics, one involved a dome presentation of a computer graphic visual projection system. Results: In all three experiments there were significant differences between dark focus activity before and after simulator exposure when comparisons were made between sick and not-sick pilot subjects. In two of these experiments, the average shift in dark focus for the sick subjects was toward increased myopia when each subject was compared to his own baseline. In the third experiment, the group showed an average shift outward of small amount and the subjects who were sick showed significantly less outward movement than those who were symptom free. Conclusions: Although the relationship is not a simple one, dark focus changes in simulator sickness imply parasympathetic activity. Because changes can occur in relation to endogenous and exogenous events, such measurement may have useful applications as dependent measures in studies of visually coupled systems, virtual reality systems, and space adaptation syndrome.

  12. Conserved Noether Currents, Utiyama's Theory of Invariant Variation, and Velocity Dependence in Local Gauge Invariance

    Science.gov (United States)

    Darvas, Gyrgy

    2009-01-01

    The paper discusses the mathematical consequences of the application of derived variables in gauge fields. Physics is aware of several phenomena, which depend first of all on velocities (like e.g., the force caused by charges moving in a magnetic field, or the Lorentz transformation). Applying the property of the second Noether theorem, that allowed generalised variables, this paper extends the article by Al-Kuwari and Taha (1991) with a new conclusion. They concluded that there are no extra conserved currents associated with local gauge invariance. We show, that in a more general case, there are further conserved Noether currents. In its method the paper reconstructs the clue introduced by Utiyama (1956, 1959) and followed by Al-Kuwari and Taha (1991) in the presence of a gauge field that depends on the co-ordinates of the velocity space. In this course we apply certain (but not full) analogies with Mills (1989). We show, that handling the space-time coordinates as implicit variables in the gauge field, reproduces the same results that have been derived in the configuration space (i.e., we do not lose information), while the proposed new treatment gives additional information extending those. The result is an extra conserved Noether current.

  13. Soft X-ray variability and the covering fraction of active galactic nuclei

    International Nuclear Information System (INIS)

    Wachter, K.W.; Strauss, M.A.; Filippenko, A.V.

    1988-01-01

    A model to explain the observed soft X-ray variability to some low-luminosity Seyfert 1 galaxies is developed. The variability is due to changes in the covering fraction of the central source as broad-line clouds move across our line of sight. A formalism is developed which is used to demonstrate how analysis of a soft X-ray light curve can provide three important quantities: the radius of the X-ray emitting region, the radius of a typical broad-line cloud, and the electron density in the cloud. It is shown that the results are rather insensitive to the assumed radial dependence of the surface brightness of the source, but are quite sensitive to a large dispersion in cloud sizes. 55 references

  14. Partner dependence and sexual risk behavior among STI clinic patients.

    Science.gov (United States)

    Senn, Theresa E; Carey, Michael P; Vanable, Peter A; Coury-Doniger, Patricia

    2010-01-01

    To investigate the relation between partner dependence and sexual risk behavior in the context of the information-motivation-behavioral skills (IMB) model. STI clinic patients (n = 1432) completed a computerized interview assessing partner dependence, condom use, and IMB variables. Men had higher partner-dependence scores than women did. Patients reporting greater dependence reported less condom use. Gender did not moderate the partner dependence-condom-use relationship. Partner dependence did not moderate the relation between IMB constructs and condom use. Further research is needed to determine how partner dependence can be incorporated into conceptual models of safer sex behaviors.

  15. Examining the causes of memory strength variability: recollection, attention failure, or encoding variability?

    Science.gov (United States)

    Koen, Joshua D; Aly, Mariam; Wang, Wei-Chun; Yonelinas, Andrew P

    2013-11-01

    A prominent finding in recognition memory is that studied items are associated with more variability in memory strength than new items. Here, we test 3 competing theories for why this occurs-the encoding variability, attention failure, and recollection accounts. Distinguishing among these theories is critical because each provides a fundamentally different account of the processes underlying recognition memory. The encoding variability and attention failure accounts propose that old item variance will be unaffected by retrieval manipulations because the processes producing this effect are ascribed to encoding. The recollection account predicts that both encoding and retrieval manipulations that preferentially affect recollection will affect memory variability. These contrasting predictions were tested by examining the effect of response speeding (Experiment 1), dividing attention at retrieval (Experiment 2), context reinstatement (Experiment 3), and increased test delay (Experiment 4) on recognition performance. The results of all 4 experiments confirm the predictions of the recollection account and are inconsistent with the encoding variability account. The evidence supporting the attention failure account is mixed, with 2 of the 4 experiments confirming the account and 2 disconfirming the account. These results indicate that encoding variability and attention failure are insufficient accounts of memory variance and provide support for the recollection account. Several alternative theoretical accounts of the results are also considered. PsycINFO Database Record (c) 2013 APA, all rights reserved.

  16. A modelling methodology for assessing the impact of climate variability and climatic change on hydroelectric generation

    International Nuclear Information System (INIS)

    Munoz, J.R.; Sailor, D.J.

    1998-01-01

    A new methodology relating basic climatic variables to hydroelectric generation was developed. The methodology can be implemented in large or small basins with any number of hydro plants. The method was applied to the Sacramento, Eel and Russian river basins in northern California where more than 100 hydroelectric plants are located. The final model predicts the availability of hydroelectric generation for the entire basin provided present and near past climate conditions, with about 90% accuracy. The results can be used for water management purposes or for analyzing the effect of climate variability on hydrogeneration availability in the basin. A wide range of results can be obtained depending on the climate change scenario used. (Author)

  17. Using Copulas in the Estimation of the Economic Project Value in the Mining Industry, Including Geological Variability

    Science.gov (United States)

    Krysa, Zbigniew; Pactwa, Katarzyna; Wozniak, Justyna; Dudek, Michal

    2017-12-01

    Geological variability is one of the main factors that has an influence on the viability of mining investment projects and on the technical risk of geology projects. In the current scenario, analyses of economic viability of new extraction fields have been performed for the KGHM Polska Miedź S.A. underground copper mine at Fore Sudetic Monocline with the assumption of constant averaged content of useful elements. Research presented in this article is aimed at verifying the value of production from copper and silver ore for the same economic background with the use of variable cash flows resulting from the local variability of useful elements. Furthermore, the ore economic model is investigated for a significant difference in model value estimated with the use of linear correlation between useful elements content and the height of mine face, and the approach in which model parameters correlation is based upon the copula best matched information capacity criterion. The use of copula allows the simulation to take into account the multi variable dependencies at the same time, thereby giving a better reflection of the dependency structure, which linear correlation does not take into account. Calculation results of the economic model used for deposit value estimation indicate that the correlation between copper and silver estimated with the use of copula generates higher variation of possible project value, as compared to modelling correlation based upon linear correlation. Average deposit value remains unchanged.

  18. Superior Intraparietal Sulcus Controls the Variability of Visual Working Memory Precision.

    Science.gov (United States)

    Galeano Weber, Elena M; Peters, Benjamin; Hahn, Tim; Bledowski, Christoph; Fiebach, Christian J

    2016-05-18

    Limitations of working memory (WM) capacity depend strongly on the cognitive resources that are available for maintaining WM contents in an activated state. Increasing the number of items to be maintained in WM was shown to reduce the precision of WM and to increase the variability of WM precision over time. Although WM precision was recently associated with neural codes particularly in early sensory cortex, we have so far no understanding of the neural bases underlying the variability of WM precision, and how WM precision is preserved under high load. To fill this gap, we combined human fMRI with computational modeling of behavioral performance in a delayed color-estimation WM task. Behavioral results replicate a reduction of WM precision and an increase of precision variability under high loads (5 > 3 > 1 colors). Load-dependent BOLD signals in primary visual cortex (V1) and superior intraparietal sulcus (IPS), measured during the WM task at 2-4 s after sample onset, were modulated by individual differences in load-related changes in the variability of WM precision. Although stronger load-related BOLD increase in superior IPS was related to lower increases in precision variability, thus stabilizing WM performance, the reverse was observed for V1. Finally, the detrimental effect of load on behavioral precision and precision variability was accompanied by a load-related decline in the accuracy of decoding the memory stimuli (colors) from left superior IPS. We suggest that the superior IPS may contribute to stabilizing visual WM performance by reducing the variability of memory precision in the face of higher load. This study investigates the neural bases of capacity limitations in visual working memory by combining fMRI with cognitive modeling of behavioral performance, in human participants. It provides evidence that the superior intraparietal sulcus (IPS) is a critical brain region that influences the variability of visual working memory precision between and

  19. The Flow of a Variable Viscosity Fluid down an Inclined Plane with a Free Surface

    Directory of Open Access Journals (Sweden)

    M. S. Tshehla

    2013-01-01

    Full Text Available The effect of a temperature dependent variable viscosity fluid flow down an inclined plane with a free surface is investigated. The fluid film is thin, so that lubrication approximation may be applied. Convective heating effects are included, and the fluid viscosity decreases exponentially with temperature. In general, the flow equations resulting from the variable viscosity model must be solved numerically. However, when the viscosity variation is small, then an asymptotic approximation is possible. The full solutions for the temperature and velocity profiles are derived using the Runge-Kutta numerical method. The flow controlling parameters such as the nondimensional viscosity variation parameter, the Biot and the Brinkman numbers, are found to have a profound effect on the resulting flow profiles.

  20. Important variables in explaining real-time peak price in the independent power market of Ontario

    International Nuclear Information System (INIS)

    Rueda, I.E.A.; Marathe, A.

    2005-01-01

    This paper uses support vector machines (SVM) based learning algorithm to select important variables that help explain the real-time peak electricity price in the Ontario market. The Ontario market was opened to competition only in May 2002. Due to the limited number of observations available, finding a set of variables that can explain the independent power market of Ontario (IMO) real-time peak price is a significant challenge for the traders and analysts. The kernel regressions of the explanatory variables on the IMO real-time average peak price show that non-linear dependencies exist between the explanatory variables and the IMO price. This non-linear relationship combined with the low variable-observation ratio rule out conventional statistical analysis. Hence, we use an alternative machine learning technique to find the important explanatory variables for the IMO real-time average peak price. SVM sensitivity analysis based results find that the IMO's predispatch average peak price, the actual import peak volume, the peak load of the Ontario market and the net available supply after accounting for load (energy excess) are some of the most important variables in explaining the real-time average peak price in the Ontario electricity market. (author)

  1. Variable selection in multivariate calibration based on clustering of variable concept.

    Science.gov (United States)

    Farrokhnia, Maryam; Karimi, Sadegh

    2016-01-01

    Recently we have proposed a new variable selection algorithm, based on clustering of variable concept (CLoVA) in classification problem. With the same idea, this new concept has been applied to a regression problem and then the obtained results have been compared with conventional variable selection strategies for PLS. The basic idea behind the clustering of variable is that, the instrument channels are clustered into different clusters via clustering algorithms. Then, the spectral data of each cluster are subjected to PLS regression. Different real data sets (Cargill corn, Biscuit dough, ACE QSAR, Soy, and Tablet) have been used to evaluate the influence of the clustering of variables on the prediction performances of PLS. Almost in the all cases, the statistical parameter especially in prediction error shows the superiority of CLoVA-PLS respect to other variable selection strategies. Finally the synergy clustering of variable (sCLoVA-PLS), which is used the combination of cluster, has been proposed as an efficient and modification of CLoVA algorithm. The obtained statistical parameter indicates that variable clustering can split useful part from redundant ones, and then based on informative cluster; stable model can be reached. Copyright © 2015 Elsevier B.V. All rights reserved.

  2. Association between increased EEG signal complexity and cannabis dependence.

    Science.gov (United States)

    Laprevote, Vincent; Bon, Laura; Krieg, Julien; Schwitzer, Thomas; Bourion-Bedes, Stéphanie; Maillard, Louis; Schwan, Raymund

    2017-12-01

    Both acute and regular cannabis use affects the functioning of the brain. While several studies have demonstrated that regular cannabis use can impair the capacity to synchronize neural assemblies during specific tasks, less is known about spontaneous brain activity. This can be explored by measuring EEG complexity, which reflects the spontaneous variability of human brain activity. A recent study has shown that acute cannabis use can affect that complexity. Since the characteristics of cannabis use can affect the impact on brain functioning, this study sets out to measure EEG complexity in regular cannabis users with or without dependence, in comparison with healthy controls. We recruited 26 healthy controls, 25 cannabis users without cannabis dependence and 14 cannabis users with cannabis dependence, based on DSM IV TR criteria. The EEG signal was extracted from at least 250 epochs of the 500ms pre-stimulation phase during a visual evoked potential paradigm. Brain complexity was estimated using Lempel-Ziv Complexity (LZC), which was compared across groups by non-parametric Kruskall-Wallis ANOVA. The analysis revealed a significant difference between the groups, with higher LZC in participants with cannabis dependence than in non-dependent cannabis users. There was no specific localization of this effect across electrodes. We showed that cannabis dependence is associated to an increased spontaneous brain complexity in regular users. This result is in line with previous results in acute cannabis users. It may reflect increased randomness of neural activity in cannabis dependence. Future studies should explore whether this effect is permanent or diminishes with cannabis cessation. Copyright © 2017 Elsevier B.V. and ECNP. All rights reserved.

  3. The solar forcing on the ground 7 Be concentration variability

    International Nuclear Information System (INIS)

    Talpos, S.; Borsan, D.H.

    2002-01-01

    7 Be, natural radionuclide, is produced by the interaction of cosmic radiation with oxygen and nitrogen molecules. 7 Be production in atmosphere depends on the intensity of cosmic radiation which is influenced by the Earth's magnetosphere. The magnetosphere shape depends on solar activity. This paper presents the influence of sunspots number (11 years period) on the ground 7 Be concentration variability. (authors)

  4. Predictors of functional dependency after stroke in Nigeria.

    Science.gov (United States)

    Ojagbemi, Akin; Owolabi, Mayowa

    2013-11-01

    The factors impacting poststroke functional dependency have not been adequately explored in sub-Saharan Africa. This study examined the risk factors for functional dependency in a group of Nigerian African stroke survivors. One hundred twenty-eight stroke survivors attending a tertiary general hospital in southwestern Nigeria were consecutively recruited and assessed for functional dependency using the modified Rankin Scale (mRS). Stroke was diagnosed according to the World Health Organization criteria. Candidate independent variables assessed included the demographic and clinical characteristics of survivors, cognitive dysfunction, and a diagnosis of major depressive disorder. Variables with significant relationship to functional dependency were entered into a logistic regression model to identify factors that were predictive of functional dependency among the stroke survivors. In all, 60.9% of the stroke survivors were functionally dependent (mRS scores≥3), with mean±SD mRS scores of 2.71±1.01. Female sex (P=.003; odds ratio [OR] 3.08; 95% confidence interval [CI] 1.47-6.44), global cognitive dysfunction (P=.002; OR 5.04; 95% CI 1.79-14.16), and major depressive disorder (Pdependency in univariate analysis. Major depressive disorder was an independent predictor of functional dependency in multivariate analysis (P<.0001; OR 6.89; 95% CI 2.55-18.6; R2=0.19). Depression, female sex, and cognitive dysfunction were strongly associated with poorer functioning after stroke. Interventions aimed at depression and cognitive dysfunction after stroke may improve functional independence in stroke survivors. Copyright © 2013 National Stroke Association. Published by Elsevier Inc. All rights reserved.

  5. A study of soil moisture variability for landmine detection by the neutron technique

    Directory of Open Access Journals (Sweden)

    Avdić Senada

    2007-01-01

    Full Text Available This paper is focused on the space and temporal variability of soil moisture experimental data acquired at a few locations near landmine fields in the Tuzla Canton, as well as on the quantification of the statistical nature of soil moisture data on a small spatial scale. Measurements of soil water content at the surface were performed by an electro-magnetic sensor over 1 25, and 100 m2 grids, at intervals of 0.2, 0.5, and 1 m, respectively. The sampling of soil moisture at different spatial resolutions and over different grid sizes has been investigated in order to achieve the quantification of the statistical nature of soil moisture distribution. The statistical characterization of spatial variability was performed through variogram and correlogram analysis of measurement results. The temporal variability of the said samples was examined over a two-season period. For both sampling periods, the spatial correlation length is about 1 to 2 m, respectively, or less. Thus, sampling should be done on a larger spatial scale, in order to capture the variability of the investigated areas. Since the characteristics of many landmine sensors depend on soil moisture, the results of this study could form a useful data base for multisensor landmine detection systems with a promising performance.

  6. Technological Capability's Predictor Variables

    Directory of Open Access Journals (Sweden)

    Fernanda Maciel Reichert

    2011-03-01

    Full Text Available The aim of this study was to identify the factors that influence in configuration of the technological capability of companies in sectors with medium-low technological intensity. To achieve the goal proposed in this article a survey was carried out. Based on the framework developed by Lall (1992 which classifies firms in basic, intermediate and advanced level of technological capability; it was found that the predominant technological capability is intermediate, with 83.7% of respondent companies (plastics companies in Brazil. It is believed that the main contribution of this study is the finding that the dependent variable named “Technological Capability” can be explained at a rate of 65% by six variables: development of new processes; selection of the best equipment supplier; sales of internally developed new technology to third parties; design and manufacture of equipment; study of the work methods and perform inventory control; and improvement of product quality.

  7. Predicting word-recognition performance in noise by young listeners with normal hearing using acoustic, phonetic, and lexical variables.

    Science.gov (United States)

    McArdle, Rachel; Wilson, Richard H

    2008-06-01

    To analyze the 50% correct recognition data that were from the Wilson et al (this issue) study and that were obtained from 24 listeners with normal hearing; also to examine whether acoustic, phonetic, or lexical variables can predict recognition performance for monosyllabic words presented in speech-spectrum noise. The specific variables are as follows: (a) acoustic variables (i.e., effective root-mean-square sound pressure level, duration), (b) phonetic variables (i.e., consonant features such as manner, place, and voicing for initial and final phonemes; vowel phonemes), and (c) lexical variables (i.e., word frequency, word familiarity, neighborhood density, neighborhood frequency). The descriptive, correlational study will examine the influence of acoustic, phonetic, and lexical variables on speech recognition in noise performance. Regression analysis demonstrated that 45% of the variance in the 50% point was accounted for by acoustic and phonetic variables whereas only 3% of the variance was accounted for by lexical variables. These findings suggest that monosyllabic word-recognition-in-noise is more dependent on bottom-up processing than on top-down processing. The results suggest that when speech-in-noise testing is used in a pre- and post-hearing-aid-fitting format, the use of monosyllabic words may be sensitive to changes in audibility resulting from amplification.

  8. Variable optical attenuator fabricated by direct UV writing

    DEFF Research Database (Denmark)

    Svalgaard, Mikael; Færch, Kjartan Ullitz; Andersen, L.U.

    2003-01-01

    It is demonstrated that direct ultraviolet writing of waveguides is a method suitable for mass production of compact variable optical attenuators with low insertion loss, low polarization-dependent loss, and high dynamic range. The fabrication setup is shown to be robust, providing good device...

  9. Assessment of hydric balance through climatic variables, in the Cazones River Basin, Veracruz, Mexico

    Directory of Open Access Journals (Sweden)

    Eduardo Santillán Gutiérrez

    2014-09-01

    Full Text Available The hydrologic regime and the water catchment capacity of a hydrographic basin depend on the temporal and spatial variation patterns of climatic variables and on the physiographic characteristics of the watershed. In certain regions, where the availability of water depends on the catchment capacity of the watershed, the utilization of effective methods such as the hydric balance has become more frequently used because it enables an estimate of the hydrologic regime, the catchment capacity, and the water flows. It also enables an estimate of the hydrologic processes and the period in which they occurred. In the present work, assessments of the Climatic Hydric Balance (CHB and of potential evapotranspiration were performed in the Cazones river basin. The calculations followed the Thornthwaite and Mather method based on climatic variables such as temperature and precipitation during the period from 1981 to 2010. As a result of these assessments, it was found that the excess layer of water and the annual runoff were 638.63 mm and 637.02 mm, respectively. Further, the work identified the months that comprise the humid and dry periods, the regime of the climatic variables, and surpluses and deficits of water in the basin during an annual cycle.

  10. Avoiding and Correcting Bias in Score-Based Latent Variable Regression with Discrete Manifest Items

    Science.gov (United States)

    Lu, Irene R. R.; Thomas, D. Roland

    2008-01-01

    This article considers models involving a single structural equation with latent explanatory and/or latent dependent variables where discrete items are used to measure the latent variables. Our primary focus is the use of scores as proxies for the latent variables and carrying out ordinary least squares (OLS) regression on such scores to estimate…

  11. Modelling Inter-relationships among water, governance, human development variables in developing countries with Bayesian networks.

    Science.gov (United States)

    Dondeynaz, C.; Lopez-Puga, J.; Carmona-Moreno, C.

    2012-04-01

    Improving Water and Sanitation Services (WSS), being a complex and interdisciplinary issue, passes through collaboration and coordination of different sectors (environment, health, economic activities, governance, and international cooperation). This inter-dependency has been recognised with the adoption of the "Integrated Water Resources Management" principles that push for the integration of these various dimensions involved in WSS delivery to ensure an efficient and sustainable management. The understanding of these interrelations appears as crucial for decision makers in the water sector in particular in developing countries where WSS still represent an important leverage for livelihood improvement. In this framework, the Joint Research Centre of the European Commission has developed a coherent database (WatSan4Dev database) containing 29 indicators from environmental, socio-economic, governance and financial aid flows data focusing on developing countries (Celine et al, 2011 under publication). The aim of this work is to model the WatSan4Dev dataset using probabilistic models to identify the key variables influencing or being influenced by the water supply and sanitation access levels. Bayesian Network Models are suitable to map the conditional dependencies between variables and also allows ordering variables by level of influence on the dependent variable. Separated models have been built for water supply and for sanitation because of different behaviour. The models are validated if complying with statistical criteria but either with scientific knowledge and literature. A two steps approach has been adopted to build the structure of the model; Bayesian network is first built for each thematic cluster of variables (e.g governance, agricultural pressure, or human development) keeping a detailed level for interpretation later one. A global model is then built based on significant indicators of each cluster being previously modelled. The structure of the

  12. Long-Term Variability in o Ceti and Other Mira Variables: Signs of Supergranular Convection?

    Science.gov (United States)

    Templeton, Matthew R.; Karovska, Margarita

    2009-09-01

    We describe our study of long-term variability of o Ceti (Mira A), the prototype of the Mira-type pulsating stars. Our study was originally undertaken to search for coherent long-period variability, but the results of our analysis didn't uncover this. However, we detected a low-frequency ``red noise'' in the Fourier spectrum of the o Ceti century-long light curve. We have since found similar behavior in other Miras and pulsating giant stars and have begun a study of a large sample of Mira variables. Similar red noise has been previously detected in red supergiants and attributed to supergranular convection. Its presence in Miras suggests the phenomenon may be ubiquitous in cool giant pulsators. These results support high-angular resolution observations of Miras and supergiants showing asymmetries in their surface brightness distributions, which may be due to large supergranular convection cells. Theoretical modeling, and numerical simulations of pulsation processes in late-type giants and supergiants should therefore take into account the effects of deep convection and large supergranular structures, which in turn may provide important insights into the behavior of Miras and other giant and supergiant pulsators. In this work, we summarize our results for o Ceti, present preliminary results of our broader study of Mira variables, and discuss how the results of this study may be used by future studies of AGB variables.

  13. Characterizing context-dependent differential firing activity in the hippocampus and entorhinal cortex.

    Science.gov (United States)

    Prerau, Michael J; Lipton, Paul A; Eichenbaum, Howard B; Eden, Uri T

    2014-04-01

    The rat hippocampus and entorhinal cortex have been shown to possess neurons with place fields that modulate their firing properties under different behavioral contexts. Such context-dependent changes in neural activity are commonly studied through electrophysiological experiments in which a rat performs a continuous spatial alternation task on a T-maze. Previous research has analyzed context-based differential firing during this task by describing differences in the mean firing activity between left-turn and right-turn experimental trials. In this article, we develop qualitative and quantitative methods to characterize and compare changes in trial-to-trial firing rate variability for sets of experimental contexts. We apply these methods to cells in the CA1 region of hippocampus and in the dorsocaudal medial entorhinal cortex (dcMEC), characterizing the context-dependent differences in spiking activity during spatial alternation. We identify a subset of cells with context-dependent changes in firing rate variability. Additionally, we show that dcMEC populations encode turn direction uniformly throughout the T-maze stem, whereas CA1 populations encode context at major waypoints in the spatial trajectory. Our results suggest scenarios in which individual cells that sparsely provide information on turn direction might combine in the aggregate to produce a robust population encoding. Copyright © 2014 Wiley Periodicals, Inc.

  14. Angular-Dependent EDMR Linewidth for Spin-Dependent Space-Charge-Limited Conduction in a Polycrystalline Pentacene

    Directory of Open Access Journals (Sweden)

    Kunito Fukuda

    2017-08-01

    Full Text Available Spin-dependent space-charge-limited carrier conduction in a Schottky barrier diode using polycrystalline p-type π-conjugated molecular pentacene is explored using multiple-frequency electrically detected magnetic resonance (EDMR spectroscopy with a variable-angle configuration. The measured EDMR spectra are decomposed into two components derived, respectively, from mobile and trapped positive polarons. The linewidth of the EDMR signal for the trapped polarons increases with increasing resonance magnetic field for an in-plane configuration where the normal vector of the device substrate is perpendicular to the resonance magnetic field, while it is independent of the field for an out-of-plane configuration. This difference is consistent with the pentacene arrangement on the device substrate, where pentacene molecules exhibit a uniaxial orientation on the out-of-substrate plane. By contrast, the mobile polarons do not show anisotropic behavior with respect to the resonance magnetic field, indicating that the anisotropic effect is averaged out owing to carrier motion. These results suggest that the orientational arrangements of polycrystalline pentacene molecules in a nano thin film play a crucial role in spin-dependent electrical conduction.

  15. Iguana: a practical data-dependent parsing framework

    NARCIS (Netherlands)

    A. Afroozeh (Ali); A. Izmaylova (Anastasia)

    2016-01-01

    textabstractData-dependent grammars extend context-free grammars with arbitrary computation, variable binding, and constraints. These features provide the user with the freedom and power to express syntactic constructs outside the realm of context-free grammars, e.g., indentation rules in Haskell

  16. Buccal dental microwear variability in extant African Hominoidea: taxonomy versus ecology.

    Science.gov (United States)

    Galbany, Jordi; Estebaranz, Ferran; Martínez, Laura M; Pérez-Pérez, Alejandro

    2009-07-01

    Buccal microwear patterns on teeth are good indicators of the abrasiveness of foodstuffs and have been used to trace the dietary habits of fossil species, including primates and hominids. However, few studies have addressed the variability of this microwear. The abrasiveness of dietary components depends not only on the hardness of the particles ingested, but also on the presence of dust and other exogenous elements introduced during food processing. These elements are responsible for the microwear typology observed on the enamel surfaces of primate teeth. Here we analyzed the variability of buccal microwear patterns in African Great Apes (Gorilla gorilla and Pan troglodytes), using tooth molds obtained from the original specimens held in several osteological collections. Our results suggest that ecological adaptations at subspecies or population level account for differences in microwear patterns, which are attributed to habitat and ecological conditions within populations rather than differences between species. The findings from studies on the variability of buccal dental microwear in extant species will contribute to a better understanding of extinct hominids' diet and ecology.

  17. Quantification of variables that affect energy consumption

    International Nuclear Information System (INIS)

    Warren, C.S.

    1993-01-01

    Facility energy consumption is the summation of a number of contributory factors, caused by equipment that uses energy in response to demands placed by the user and according to its particular design. While energy efficiency improvements usually concentrate on individual parts or systems, overall energy consumption is analyzed by examining the use of specific fuels. Because independent variables effect the consumption of these fuels, accurate comparisons of a facility's energy consumption for time-measured periods must include these effects. In many cases, it is possible to determine and quantify the effects of one or more of the independent variables through a statistically valid regression analysis of the data. The regression model can be linear, or be dependent on other functions such as powers, time lead or lag, or exponential. The most common model is linear, but other dependencies are often encountered. Regression analyses are not difficult to accomplish, and are included as one of the tools in most spreadsheet software. The analyses provide the energy manager with a means to better understand the energy consumption of his/her facility

  18. A stochastic Galerkin method for the Euler equations with Roe variable transformation

    KAUST Repository

    Pettersson, Per; Iaccarino, Gianluca; Nordströ m, Jan

    2014-01-01

    The Euler equations subject to uncertainty in the initial and boundary conditions are investigated via the stochastic Galerkin approach. We present a new fully intrusive method based on a variable transformation of the continuous equations. Roe variables are employed to get quadratic dependence in the flux function and a well-defined Roe average matrix that can be determined without matrix inversion.In previous formulations based on generalized polynomial chaos expansion of the physical variables, the need to introduce stochastic expansions of inverse quantities, or square roots of stochastic quantities of interest, adds to the number of possible different ways to approximate the original stochastic problem. We present a method where the square roots occur in the choice of variables, resulting in an unambiguous problem formulation.The Roe formulation saves computational cost compared to the formulation based on expansion of conservative variables. Moreover, the Roe formulation is more robust and can handle cases of supersonic flow, for which the conservative variable formulation fails to produce a bounded solution. For certain stochastic basis functions, the proposed method can be made more effective and well-conditioned. This leads to increased robustness for both choices of variables. We use a multi-wavelet basis that can be chosen to include a large number of resolution levels to handle more extreme cases (e.g. strong discontinuities) in a robust way. For smooth cases, the order of the polynomial representation can be increased for increased accuracy. © 2013 Elsevier Inc.

  19. morphological characterization and variability study of african yam ...

    African Journals Online (AJOL)

    abc

    Characterisation of Sphenostylis stenocarpa (Hochst ex A. Rich) Harms (African yam bean) was carried out to determine the degree ... the differences in the accessions of S.stenocarpa could be explored in breeding programme for improved crop. KEYWORDS: ... programme for AYB would depend on the genetic variability ...

  20. The value of using seasonality and meteorological variables to model intra-urban PM2.5 variation

    Science.gov (United States)

    Olvera Alvarez, Hector A.; Myers, Orrin B.; Weigel, Margaret; Armijos, Rodrigo X.

    2018-06-01

    A yearlong air monitoring campaign was conducted to assess the impact of local temperature, relative humidity, and wind speed on the temporal and spatial variability of PM2.5 in El Paso, Texas. Monitoring was conducted at four sites purposely selected to capture the local traffic variability. Effects of meteorological events on seasonal PM2.5 variability were identified. For instance, in winter low-wind and low-temperature conditions were associated with high PM2.5 events that contributed to elevated seasonal PM2.5 levels. Similarly, in spring, high PM2.5 events were associated with high-wind and low-relative humidity conditions. Correlation coefficients between meteorological variables and PM2.5 fluctuated drastically across seasons. Specifically, it was observed that for most sites correlations between PM2.5 and meteorological variables either changed from positive to negative or dissolved depending on the season. Overall, the results suggest that mixed effects analysis with season and site as fixed factors and meteorological variables as covariates could increase the explanatory value of LUR models for PM2.5.

  1. Updating prognosis in primary biliary cirrhosis using a time-dependent Cox regression model. PBC1 and PBC2 trial groups

    DEFF Research Database (Denmark)

    Christensen, E; Altman, D G; Neuberger, J

    1993-01-01

    BACKGROUND: The precision of current prognostic models in primary biliary cirrhosis (PBC) is rather low, partly because they are based on data from just one time during the course of the disease. The aim of this study was to design a new, more precise prognostic model by incorporating follow......-up data in the development of the model. METHODS: We have performed Cox regression analyses with time-dependent variables in 237 PBC patients followed up regularly for up to 11 years. The validity of the obtained models was tested by comparing predicted and observed survival in 147 independent PBC...... patients followed for up to 6 years. RESULTS: In the obtained model the following time-dependent variables independently indicated a poor prognosis: high bilirubin, low albumin, ascites, gastrointestinal bleeding, and old age. When including histological variables, cirrhosis, central cholestasis, and low...

  2. Impact of Subsurface Temperature Variability on Meteorological Variability: An AGCM Study

    Science.gov (United States)

    Mahanama, S. P.; Koster, R. D.; Liu, P.

    2006-05-01

    Anomalous atmospheric conditions can lead to surface temperature anomalies, which in turn can lead to temperature anomalies deep in the soil. The deep soil temperature (and the associated ground heat content) has significant memory -- the dissipation of a temperature anomaly may take weeks to months -- and thus deep soil temperature may contribute to the low frequency variability of energy and water variables elsewhere in the system. The memory may even provide some skill to subseasonal and seasonal forecasts. This study uses two long-term AGCM experiments to isolate the contribution of deep soil temperature variability to variability elsewhere in the climate system. The first experiment consists of a standard ensemble of AMIP-type simulations, simulations in which the deep soil temperature variable is allowed to interact with the rest of the system. In the second experiment, the coupling of the deep soil temperature to the rest of the climate system is disabled -- at each grid cell, the local climatological seasonal cycle of deep soil temperature (as determined from the first experiment) is prescribed. By comparing the variability of various atmospheric quantities as generated in the two experiments, we isolate the contribution of interactive deep soil temperature to that variability. The results show that interactive deep soil temperature contributes significantly to surface temperature variability. Interactive deep soil temperature, however, reduces the variability of the hydrological cycle (evaporation and precipitation), largely because it allows for a negative feedback between evaporation and temperature.

  3. Interannual variability of growth and reproduction in Bursera simaruba: the role of allometry and resource variability.

    Science.gov (United States)

    Hulshof, Catherine M; Stegen, James C; Swenson, Nathan G; Enquist, Carolyn A F; Enquist, Brian J

    2012-01-01

    Plants are expected to differentially allocate resources to reproduction, growth, and survival in order to maximize overall fitness. Life history theory predicts that the allocation of resources to reproduction should occur at the expense of vegetative growth. Although it is known that both organism size and resource availability can influence life history traits, few studies have addressed how size dependencies of growth and reproduction and variation in resource supply jointly affect the coupling between growth and reproduction. In order to understand the relationship between growth and reproduction in the context of resource variability, we utilize a long-term observational data set consisting of 670 individual trees over a 10-year period within a local population of Bursera simaruba (L.) Sarg. We (1) quantify the functional form and variability in the growth-reproduction relationship at the population and individual-tree level and (2) develop a theoretical framework to understand the allometric dependence of growth and reproduction. Our findings suggest that the differential responses of allometric growth and reproduction to resource availability, both between years and between microsites, underlie the apparent relationship between growth and reproduction. Finally, we offer an alternative approach for quantifying the relationship between growth and reproduction that accounts for variation in allometries.

  4. Estimating the price elasticity of beer: meta-analysis of data with heterogeneity, dependence, and publication bias.

    Science.gov (United States)

    Nelson, Jon P

    2014-01-01

    Precise estimates of price elasticities are important for alcohol tax policy. Using meta-analysis, this paper corrects average beer elasticities for heterogeneity, dependence, and publication selection bias. A sample of 191 estimates is obtained from 114 primary studies. Simple and weighted means are reported. Dependence is addressed by restricting number of estimates per study, author-restricted samples, and author-specific variables. Publication bias is addressed using funnel graph, trim-and-fill, and Egger's intercept model. Heterogeneity and selection bias are examined jointly in meta-regressions containing moderator variables for econometric methodology, primary data, and precision of estimates. Results for fixed- and random-effects regressions are reported. Country-specific effects and sample time periods are unimportant, but several methodology variables help explain the dispersion of estimates. In models that correct for selection bias and heterogeneity, the average beer price elasticity is about -0.20, which is less elastic by 50% compared to values commonly used in alcohol tax policy simulations. Copyright © 2013 Elsevier B.V. All rights reserved.

  5. Contrasting gender differences on two measures of exercise dependence.

    Science.gov (United States)

    Weik, M; Hale, B D

    2009-03-01

    Recent studies using multidimensional measures have shown that men (Exercise Dependence Scale; EDS-R) are more exercise-dependent than women, whereas others have found that women (Exercise Dependence Questionnaire; EDQ) are more exercise-dependent than men. This study investigated whether there may be sex differences in exercise dependence or whether the questionnaires may be measuring different dimensions of exercise dependence. Regular exercisers voluntarily completed the EDS-R, EDQ and Drive for Thinness (DFT) subscale before or after a workout. A local health club in the eastern USA. Male (n = 102) and female (n = 102) exercisers completed the three questionnaires, but 11 participants (1 man, 10 women) were excluded from further analysis because scores indicated possible secondary exercise dependence (eating disorder). Eight subscales of the EDQ, seven subscales of the EDS, the DFT subscale, and several demographic variables served as dependent measures. A multivariate analysis of variance (MANOVA) on the EDS-R showed that men were significantly higher than women on the Withdrawal, Continuance, Tolerance, Lack of Control, Time, and Intention Effect subscales. Another MANOVA on the EDQ indicated that women scored significantly higher than did men on the Interference, Positive Rewards, Withdrawal, and Social Reasons subscales. Statistical analysis using t tests revealed that men had significantly higher total EDS-R scores than women, but women had significantly higher EDQ and DFT scores. These results suggest that both questionnaires measure different aspects of exercise dependence that favour either gender. It remains for further research to determine whether these instruments are equally viable for measurement of ED in both men and women.

  6. Flicker Study on Variable Speed Wind Turbines with Permanent Magnet Synchronous Generator

    DEFF Research Database (Denmark)

    Hu, Weihao; Chen, Zhe; Wang, Yue

    2008-01-01

    capacity, grid impedance angle) are analyzed. Flicker mitigation is realized by output reactive power control of the variable speed wind turbines with PMSG. Simulation results show the output reactive power control is an effective measure to mitigate the flicker during continuous operation of grid......Grid connected wind turbines are fluctuating power sources that may produce flicker during continuous operation. This paper presents a simulation model of a MW-level variable speed wind turbines with a permanent magnet synchronous generator (PMSG) and a full-scale converter developed...... in the simulation tool of PSCAD/EMTDC. Flicker emission of this system is investigated during continuous operation. The dependence of flicker emission on wind characteristics (mean speed, turbulence intensity), 3p torque oscillations due to wind shear and tower shadow effects and grid conditions (short circuit...

  7. Variable intertidal temperature explains why disease endangers black abalone

    Science.gov (United States)

    Ben-Horin, Tal; Lenihan, Hunter S.; Lafferty, Kevin D.

    2013-01-01

    Epidemiological theory suggests that pathogens will not cause host extinctions because agents of disease should fade out when the host population is driven below a threshold density. Nevertheless, infectious diseases have threatened species with extinction on local scales by maintaining high incidence and the ability to spread efficiently even as host populations decline. Intertidal black abalone (Haliotis cracherodii), but not other abalone species, went extinct locally throughout much of southern California following the emergence of a Rickettsiales-like pathogen in the mid-1980s. The rickettsial disease, a condition known as withering syndrome (WS), and associated mortality occur at elevated water temperatures. We measured abalone body temperatures in the field and experimentally manipulated intertidal environmental conditions in the laboratory, testing the influence of mean temperature and daily temperature variability on key epizootiological processes of WS. Daily temperature variability increased the susceptibility of black abalone to infection, but disease expression occurred only at warm water temperatures and was independent of temperature variability. These results imply that high thermal variation of the marine intertidal zone allows the pathogen to readily infect black abalone, but infected individuals remain asymptomatic until water temperatures periodically exceed thresholds modulating WS. Mass mortalities can therefore occur before pathogen transmission is limited by density-dependent factors.

  8. Hardness variability in commercial technologies

    International Nuclear Information System (INIS)

    Shaneyfelt, M.R.; Winokur, P.S.; Meisenheimer, T.L.; Sexton, F.W.; Roeske, S.B.; Knoll, M.G.

    1994-01-01

    The radiation hardness of commercial Floating Gate 256K E 2 PROMs from a single diffusion lot was observed to vary between 5 to 25 krad(Si) when irradiated at a low dose rate of 64 mrad(Si)/s. Additional variations in E 2 PROM hardness were found to depend on bias condition and failure mode (i.e., inability to read or write the memory), as well as the foundry at which the part was manufactured. This variability is related to system requirements, and it is shown that hardness level and variability affect the allowable mode of operation for E 2 PROMs in space applications. The radiation hardness of commercial 1-Mbit CMOS SRAMs from Micron, Hitachi, and Sony irradiated at 147 rad(Si)/s was approximately 12, 13, and 19 krad(Si), respectively. These failure levels appear to be related to increases in leakage current during irradiation. Hardness of SRAMs from each manufacturer varied by less than 20%, but differences between manufacturers are significant. The Qualified Manufacturer's List approach to radiation hardness assurance is suggested as a way to reduce variability and to improve the hardness level of commercial technologies

  9. Profiles of drug addicts in relation to personality variables and disorders.

    Science.gov (United States)

    Carou, María; Romero, Estrella; Luengo, Mª Ángeles

    2016-10-07

    In recent decades, research has identified a set of impulsive/disinhibited personality variables closely associated with drug addiction. As well as this, disorders linked with these variables, such as ADHD and personality disorders, are being closely studied in the field of drug addiction. Although much knowledge has been accumulated about the relation of these variables and disorders taken separately, less is known about how these constructs allow identify-specific profiles within the drug dependent population to be identified. This work, on the basis of data collected on a sample of drug addicts in treatment, analyzes how impulsiveness, sensation seeking, self-control, ADHD and personality disorders contribute to identifying specific profiles of addicts. Cluster analysis allowed two profiles to be outlined according to these personality and psychopathology characteristics. Self-control, impulsiveness, impulsive and antisocial personality disorders, as well as scores in ADHD, emerge as the variables that contribute more to profile differentiation. One of these profiles (56.1% of participants) with a high disinhibition pattern, is associated with severe indicators of consumption and criminal career patterns. These results allow us to emphasize the role of personality and impulsiveness-related disorders in the identification of distinctive profiles within the addict population, and suggest the need to generate treatment strategies adapted to personal/psychopathology configurations of drug addicts.

  10. Comparison between OpenFOAM CFD & BEM theory for variable speed – variable pitch HAWT

    Directory of Open Access Journals (Sweden)

    ElQatary Islam

    2014-01-01

    Full Text Available OpenFoam is used to compare computational fluid dynamics (CFD with blade element momentum theory (BEM for a variable speed - variable pitch HAWT (Horizontal Axis Wind Turbine. The wind turbine is first designed using the BEM to determine the blade chord, twist and operating conditions. The wind turbine blade has an outer diameter of 14 m, uses a NACA 63–415 profile for the entire blade and root to tip twist distribution of 15deg (Figure 3. The RPM varies from 20–75 for freestream velocities varying between 3–10.5 m/s (variable speed and a constant RPM of 78.78 for velocities ranging between 11–25 m/s (variable pitch. OpenFOAM is used to investigate the wind turbine performance at several operating points including cut-in wind speed (3 m/s, rated wind speed (10.5 m/s and in the variable pitch zone. Simulation results show that in the variable-speed operating range, both CFD and BEM compare reasonably well. This agreement can be attributed to the fact that the complex three-dimensional flow around the turbine blades can be split into two radial segments. For radii less than the mid-span, the flow is three-dimensional, whereas for radii greater than the mid-span, the flow is approximately two-dimensional. Since the majority of the power is produced from sections beyond the mid-span, the agreement between CFD and BEM is reasonable. For the variable-pitch operating range the CFD results and BEM deviate considerably. In this case the majority of the power is produced from the inner sections in which the flow is three-dimensional and can no longer be predicted by the BEM. The results show that differences in pitch angles up to 10deg can result to regulate the power for high wind speeds in the variable-pitch operation zone.

  11. Information content of neural networks with self-control and variable activity

    International Nuclear Information System (INIS)

    Bolle, D.; Amari, S.I.; Dominguez Carreta, D.R.C.; Massolo, G.

    2001-01-01

    A self-control mechanism for the dynamics of neural networks with variable activity is discussed using a recursive scheme for the time evolution of the local field. It is based upon the introduction of a self-adapting time-dependent threshold as a function of both the neural and pattern activity in the network. This mechanism leads to an improvement of the information content of the network as well as an increase of the storage capacity and the basins of attraction. Different architectures are considered and the results are compared with numerical simulations

  12. Multiple cyber attacks against a target with observation errors and dependent outcomes: Characterization and optimization

    International Nuclear Information System (INIS)

    Hu, Xiaoxiao; Xu, Maochao; Xu, Shouhuai; Zhao, Peng

    2017-01-01

    In this paper we investigate a cybersecurity model: An attacker can launch multiple attacks against a target with a termination strategy that says that the attacker will stop after observing a number of successful attacks or when the attacker is out of attack resources. However, the attacker's observation of the attack outcomes (i.e., random variables indicating whether the target is compromised or not) has an observation error that is specified by both a false-negative and a false-positive probability. The novelty of the model we study is the accommodation of the dependence between the attack outcomes, because the dependence was assumed away in the literature. In this model, we characterize the monotonicity and bounds of the compromise probability (i.e., the probability that the target is compromised). In addition to extensively showing the impact of dependence on quantities such as compromise probability and attack cost, we give methods for finding the optimal strategy that leads to maximum compromise probability or minimum attack cost. This study highlights that the dependence between random variables cannot be assumed away, because the results will be misleading. - Highlights: • A novel cybersecurity model is proposed to accommodate the dependence among attack outcomes. • The monotonicity and bounds of the compromise probability are studied. • The dependence effect on the compromise probability and attack cost is discussed via simulation. • The optimal strategy that leads to maximum compromise probability or minimum attack cost is presented.

  13. An efficient source of continuous variable polarization entanglement

    DEFF Research Database (Denmark)

    Dong, R.; Heersink, J.; Yoshikawa, J.-I.

    2007-01-01

    classical excitation in Ŝ3. Polarization entanglement was generated by interfering two independent polarization squeezed fields on a symmetric beam splitter. The resultant beams exhibit strong quantum noise correlations in the dark Ŝ1-Ŝ2 polarization plane. To verify entanglement generation, we......We have experimentally demonstrated the efficient creation of highly entangled bipartite continuous variable polarization states. Exploiting an optimized scheme for the production of squeezing using the Kerr non-linearity of a glass fibre we generated polarization squeezed pulses with a mean...... was found to depend critically on the beam-splitting ratio of the entangling beam splitter. Carrying out measurements on a different set of conjugate Stokes parameters, correlations of -3.6 ±0.3 and -3.4 ±0.3 dB have been observed. This result is more robust against asymmetries in the entangling beam...

  14. Partitioning inter annual variability in net ecosystem exchange between climatic variability and functional change

    International Nuclear Information System (INIS)

    Hui, D.; Luo, Y.; Katul, G.

    2003-01-01

    Inter annual variability in net ecosystem exchange of carbon is investigated using a homogeneity-of-slopes model to identify the function change contributing to inter annual variability, net ecosystem carbon exchange, and night-time ecosystem respiration. Results of employing this statistical approach to a data set collected at the Duke Forest AmeriFlux site from August 1997 to December 2001 are discussed. The results demonstrate that it is feasible to partition the variation in ecosystem carbon fluxes into direct effects of seasonal and inter annual climatic variability and functional change. 51 refs., 4 tabs., 5 figs

  15. Disease in a more variable and unpredictable climate

    Science.gov (United States)

    McMahon, T. A.; Raffel, T.; Rohr, J. R.; Halstead, N.; Venesky, M.; Romansic, J.

    2014-12-01

    Global climate change is shifting the dynamics of infectious diseases of humans and wildlife with potential adverse consequences for disease control. Despite this, the role of global climate change in the decline of biodiversity and the emergence of infectious diseases remains controversial. Climate change is expected to increase climate variability in addition to increasing mean temperatures, making climate less predictable. However, few empirical or theoretical studies have considered the effects of climate variability or predictability on disease, despite it being likely that hosts and parasites will have differential responses to climatic shifts. Here we present a theoretical framework for how temperature variation and its predictability influence disease risk by affecting host and parasite acclimation responses. Laboratory experiments and field data on disease-associated frog declines in Latin America support this framework and provide evidence that unpredictable temperature fluctuations, on both monthly and diurnal timescales, decrease frog resistance to the pathogenic chytrid fungus Batrachochytrium dendrobatidis (Bd). Furthermore, the pattern of temperature-dependent growth of the fungus on frogs was inconsistent with the pattern of Bd growth in culture, emphasizing the importance of accounting for the host-parasite interaction when predicting climate-dependent disease dynamics. Consistent with our laboratory experiments, increased regional temperature variability associated with global El Niño climatic events was the best predictor of widespread amphibian losses in the genus Atelopus. Thus, incorporating the effects of small-scale temporal variability in climate can greatly improve our ability to predict the effects of climate change on disease.

  16. Reinforcing Saccadic Amplitude Variability

    Science.gov (United States)

    Paeye, Celine; Madelain, Laurent

    2011-01-01

    Saccadic endpoint variability is often viewed as the outcome of neural noise occurring during sensorimotor processing. However, part of this variability might result from operant learning. We tested this hypothesis by reinforcing dispersions of saccadic amplitude distributions, while maintaining constant their medians. In a first experiment we…

  17. Utilization technique on variable speed device

    International Nuclear Information System (INIS)

    1989-12-01

    This reports of workshop on power technology describes using technique on variable speed device, which deals with alternating current situation and prospect of current variable speed device, technical trend and prospect of electronics, reduce expenses by variable speed device, control technique, measurement technology, high voltage variable speed device, recent trend of inverter technology, low voltage and high voltage variable speed device control device, operating variable speed device in cooling fan, FDF application and defect case of variable speed device, cooling pump application of water variable transformer, inverter application and energy effect of ventilation equipment, application of variable speed device and analysis of the result of operation and study for application of variable speed technology.

  18. Results of scalp cooling during anthracycline containing chemotherapy depend on scalp skin temperature

    NARCIS (Netherlands)

    Komen, M.M.; Smorenburg, C.H.; Nortier, J.W.; Ploeg, T. van der; Hurk, C.J. van den; Hoeven, J.J. van der

    2016-01-01

    OBJECTIVES: The success of scalp cooling in preventing or reducing chemotherapy induced alopecia (CIA) is highly variable between patients undergoing similar chemotherapy regimens. A decrease of the scalp skin temperature seems to be an important factor, but data on the optimum temperature reached

  19. The MEXSAS2 Sample and the Ensemble X-ray Variability of Quasars

    Energy Technology Data Exchange (ETDEWEB)

    Serafinelli, Roberto [Dipartimento di Fisica, Università di Roma Tor Vergata, Rome (Italy); Dipartimento di Fisica, Università di Roma Sapienza, Rome (Italy); Vagnetti, Fausto; Chiaraluce, Elia [Dipartimento di Fisica, Università di Roma Tor Vergata, Rome (Italy); Middei, Riccardo, E-mail: roberto.serafinelli@roma2.infn.it [Dipartimento di Matematica e Fisica, Università Roma Tre, Rome (Italy)

    2017-10-11

    We present the second Multi-Epoch X-ray Serendipitous AGN Sample (MEXSAS2), extracted from the 6th release of the XMM Serendipitous Source Catalog (XMMSSC-DR6), cross-matched with Sloan Digital Sky Survey quasar Catalogs DR7Q and DR12Q. Our sample also includes the available measurements for masses, bolometric luminosities, and Eddington ratios. Analyses of the ensemble structure function and spectral variability are presented, together with their dependences on such parameters. We confirm a decrease of the structure function with the X-ray luminosity, and find a weak dependence on the black hole mass. We introduce a new spectral variability estimator, taking errors on both fluxes and spectral indices into account. We confirm an ensemble softer when brighter trend, with no dependence of such estimator on black hole mass, Eddington ratio, redshift, X-ray and bolometric luminosity.

  20. A study of variable thrust, variable specific impulse trajectories for solar system exploration

    Science.gov (United States)

    Sakai, Tadashi

    A study has been performed to determine the advantages and disadvantages of variable thrust and variable Isp (specific impulse) trajectories for solar system exploration. There have been several numerical research efforts for variable thrust, variable Isp, power-limited trajectory optimization problems. All of these results conclude that variable thrust, variable Isp (variable specific impulse, or VSI) engines are superior to constant thrust, constant Isp (constant specific impulse; or CSI) engines. However, most of these research efforts assume a mission from Earth to Mars, and some of them further assume that these planets are circular and coplanar. Hence they still lack the generality. This research has been conducted to answer the following questions: (1) Is a VSI engine always better than a CSI engine or a high thrust engine for any mission to any planet with any time of flight considering lower propellant mass as the sole criterion? (2) If a planetary swing-by is used for a VSI trajectory, is the fuel savings of a VSI swing-by trajectory better than that of a CSI swing-by or high thrust swing-by trajectory? To support this research, an unique, new computer-based interplanetary trajectory calculation program has been created. This program utilizes a calculus of variations algorithm to perform overall optimization of thrust, Isp, and thrust vector direction along a trajectory that minimizes fuel consumption for interplanetary travel. It is assumed that the propulsion system is power-limited, and thus the compromise between thrust and Isp is a variable to be optimized along the flight path. This program is capable of optimizing not only variable thrust trajectories but also constant thrust trajectories in 3-D space using a planetary ephemeris database. It is also capable of conducting planetary swing-bys. Using this program, various Earth-originating trajectories have been investigated and the optimized results have been compared to traditional CSI and high

  1. Spatiotemporal variability of marine renewable energy resources in Norway

    NARCIS (Netherlands)

    Varlas, George; Christakos, Konstantinos; Cheliotis, Ioannis; Papadopoulos, A.; Steeneveld, G.J.

    2017-01-01

    Marine Renewable Energy (MRE) resources such as wind and wave energy depend on the complex behaviour of weather and climatic conditions which determine the development of MRE technologies, energy grid, supply and prices. This study investigates the spatiotemporal variability of MRE resources along

  2. Simulation of time-dependent Heisenberg models in one dimension

    DEFF Research Database (Denmark)

    Volosniev, A. G.; Hammer, H. -W.; Zinner, N. T.

    2016-01-01

    In this Letter, we provide a theoretical analysis of strongly interacting quantum systems confined by a time-dependent external potential in one spatial dimension. We show that such systems can be used to simulate spin chains described by Heisenberg Hamiltonians in which the exchange coupling...... constants can be manipulated by time-dependent driving of the shape of the external confinement. As illustrative examples, we consider a harmonic trapping potential with a variable frequency and an infinite square well potential with a time-dependent barrier in the middle....

  3. TIME-DEPENDENT TURBULENT HEATING OF OPEN FLUX TUBES IN THE CHROMOSPHERE, CORONA, AND SOLAR WIND

    Energy Technology Data Exchange (ETDEWEB)

    Woolsey, L. N.; Cranmer, S. R., E-mail: lwoolsey@cfa.harvard.edu [Harvard-Smithsonian Center for Astrophysics, 60 Garden St., Cambridge, MA 02138 (United States)

    2015-10-01

    We investigate several key questions of plasma heating in open-field regions of the corona that connect to the solar wind. We present results for a model of Alfvén-wave-driven turbulence for three typical open magnetic field structures: a polar coronal hole, an open flux tube neighboring an equatorial streamer, and an open flux tube near a strong-field active region. We compare time-steady, one-dimensional turbulent heating models against fully time-dependent three-dimensional reduced-magnetohydrodynamic modeling of BRAID. We find that the time-steady results agree well with time-averaged results from BRAID. The time dependence allows us to investigate the variability of the magnetic fluctuations and of the heating in the corona. The high-frequency tail of the power spectrum of fluctuations forms a power law whose exponent varies with height, and we discuss the possible physical explanation for this behavior. The variability in the heating rate is bursty and nanoflare-like in nature, and we analyze the amount of energy lost via dissipative heating in transient events throughout the simulation. The average energy in these events is 10{sup 21.91} erg, within the “picoflare” range, and many events reach classical “nanoflare” energies. We also estimated the multithermal distribution of temperatures that would result from the heating-rate variability, and found good agreement with observed widths of coronal differential emission measure distributions. The results of the modeling presented in this paper provide compelling evidence that turbulent heating in the solar atmosphere by Alfvén waves accelerates the solar wind in open flux tubes.

  4. Interannual variability: a crucial component of space use at the territory level.

    Science.gov (United States)

    Uboni, Alessia; Vucetich, John A; Stahler, Daniel R; Smith, Douglas W

    2015-01-01

    Interannual variability in space use and how that variation is influenced by density-dependent and density-independent factors are important processes in population ecology. Nevertheless, interannual variability has been neglected by the majority of space use studies. We assessed that variation for wolves living in 15 different packs within Yellowstone National Park during a 13-year period (1996-2008). We estimated utilization distributions to quantify the intensity of space use within each pack's territory each year in summer and winter. Then, we used the volume of intersection index (VI) to quantify the extent to which space use varied from year to year. This index accounts for both the area of overlap and differences in the intensity of use throughout a territory and ranges between 0 and 1. The mean VI index was 0.49, and varied considerably, with approximately 20% of observations (n = 230) being 0.7. In summer, 42% of the variation was attributable to differences between packs. These differences can be attributable to learned behaviors and had never been thought to have such an influence on space use. In winter, 34% of the variation in overlap between years was attributable to interannual differences in precipitation and pack size. This result reveals the strong influence of climate on predator space use and underlies the importance of understanding how climatic factors are going to affect predator populations in the occurrence of climate change. We did not find any significant association between overlap and variables representing density-dependent processes (elk and wolf densities) or intraspecific competition (ratio of wolves to elk). This last result poses a challenge to the classic view of predator-prey systems. On a small spatial scale, predator space use may be driven by factors other than prey distribution.

  5. A deterministic inventory model for deteriorating items with selling price dependent demand and three-parameter Weibull distributed deterioration

    Directory of Open Access Journals (Sweden)

    Asoke Kumar Bhunia

    2014-06-01

    Full Text Available In this paper, an attempt is made to develop two inventory models for deteriorating items with variable demand dependent on the selling price and frequency of advertisement of items. In the first model, shortages are not allowed whereas in the second, these are allowed and partially backlogged with a variable rate dependent on the duration of waiting time up to the arrival of next lot. In both models, the deterioration rate follows three-parameter Weibull distribution and the transportation cost is considered explicitly for replenishing the order quantity. This cost is dependent on the lot-size as well as the distance from the source to the destination. The corresponding models have been formulated and solved. Two numerical examples have been considered to illustrate the results and the significant features of the results are discussed. Finally, based on these examples, the effects of different parameters on the initial stock level, shortage level (in case of second model only, cycle length along with the optimal profit have been studied by sensitivity analyses taking one parameter at a time keeping the other parameters as same.

  6. Heterogeneity of emotional and interpersonal difficulties in alcohol-dependence: A cluster analytic approach.

    Science.gov (United States)

    Maurage, Pierre; Timary, Philippe de; D'Hondt, Fabien

    2017-08-01

    Emotional and interpersonal impairments have been largely reported in alcohol-dependence, and their role in its development and maintenance is widely established. However, earlier studies have exclusively focused on group comparisons between healthy controls and alcohol-dependent individuals, considering them as a homogeneous population. The variability of socio-emotional profiles in this disorder thus remains totally unexplored. The present study used a cluster analytic approach to explore the heterogeneity of affective and social disorders in alcohol-dependent individuals. 296 recently-detoxified alcohol-dependent patients were first compared with 246 matched healthy controls regarding self-reported emotional (i.e. alexithymia) and social (i.e. interpersonal problems) difficulties. Then, a cluster analysis was performed, focusing on the alcohol-dependent sample, to explore the presence of differential patterns of socio-emotional deficits and their links with demographic, psychopathological and alcohol-related variables. The group comparison between alcohol-dependent individuals and controls clearly confirmed that emotional and interpersonal difficulties constitute a key factor in alcohol-dependence. However, the cluster analysis identified five subgroups of alcohol-dependent individuals, presenting distinct combinations of alexithymia and interpersonal problems ranging from a total absence of reported impairment to generalized socio-emotional difficulties. Alcohol-dependent individuals should no more be considered as constituting a unitary group regarding their affective and interpersonal difficulties, but rather as a population encompassing a wide variety of socio-emotional profiles. Future experimental studies on emotional and social variables should thus go beyond mere group comparisons to explore this heterogeneity, and prevention programs proposing an individualized evaluation and rehabilitation of these deficits should be promoted. Copyright © 2017

  7. Methods for Minimization and Management of Variability in Long-Term Groundwater Monitoring Results

    Science.gov (United States)

    2015-12-01

    DECEMBER 2015 Poonam Kulkarni Charles Newell Claire Krebs Thomas McHugh GSI Environmental, Inc. Britt Sanford ProHydro Distribution...based on an understanding of the short-term variability and long-term attenuation rate at a particular site ( McHugh et al., 2015a). The...time is independent of these parameters ( McHugh et al., 2015c). The relative trade-off between monitoring frequency and time required to

  8. Neonatal vitamin K might reduce vulnerability to alcohol dependence in Danish men

    DEFF Research Database (Denmark)

    Manzardo, Ann M; Penick, Elizabeth C; Knop, Joachim

    2005-01-01

    structures is particularly active. Taking advantage of a serendipitous event in the history of treating newborns, we tested the hypothesis that vitamin K supplementation, administered to facilitate the synthesis of blood-clotting proteins within this critical timeframe, might also reduce the development...... on for this article (N = 238), 44 received vitamin K supplementation at birth; 161 were considered high risk, and 66 were categorized as having lower birth weight (.... The Diagnostic and Statistical Manual of Mental Disorders, Third Edition, Revised, diagnosis of alcohol dependence and a measure of lifetime problem drinking served as the 30-year outcome variables. RESULTS: Vitamin K treatment, inherited risk and low birth weight each independently predicted alcohol dependence...

  9. Seasonal variability in clinical care of COPD outpatients: results from the Andalusian COPD audit

    Directory of Open Access Journals (Sweden)

    López-Campos JL

    2017-03-01

    Full Text Available Jose Luis López-Campos,1,2 Maria Abad Arranz,1 Carmen Calero-Acuña,1,2 Fernando Romero-Valero,3 Ruth Ayerbe-García,4 Antonio Hidalgo-Molina,3 Ricardo I Aguilar-Pérez-Grovas,4 Francisco García-Gil,5 Francisco Casas-Maldonado,6 Laura Caballero-Ballesteros,5 María Sánchez-Palop,6 Dolores Pérez-Tejero,7 Alejandro Segado Soriano,7 Jose Calvo-Bonachera,8 Bárbara Hernández-Sierra,8 Adolfo Doménech,9 Macarena Arroyo-Varela,9 Francisco González-Vargas,10 Juan J Cruz-Rueda10 1Unidad Médico-Quirúrgica de Enfermedades Respiratorias, Instituto de Biomedicina de Sevilla (IBiS, Hospital Universitario Virgen del Rocío/Universidad de Sevilla, Seville, 2CIBER de Enfermedades Respiratorias (CIBERES, Instituto de Salud Carlos III, Madrid, 3Sección de Neumología, Hospital Puerta del Mar, Cádiz, 4Servicio de Neumología, Hospital Juan Ramón Jiménez, Huelva, 5Servicio de Neumología, Hospital Universitario Reina Sofía, Córdoba, 6Servicio de Neumología, Hospital Universitario San Cecilio, Granada, 7Sección de Neumología, Hospital Infanta Margarita, Cabra, Córdoba, 8Servicio de Neumología, Hospital Torrecárdenas, Almería, 9Servicio de Neumología, Hospital Regional Universitario de Málaga, Málaga, 10Servicio de Neumología, Hospital Universitario Virgen de las Nieves, Granada, Spain Objectives: Clinical practice in chronic obstructive pulmonary disease (COPD can be influenced by weather variability throughout the year. To explore the hypothesis of seasonal variability in clinical practice, the present study analyzes the results of the 2013–2014 Andalusian COPD audit with regard to changes in clinical practice according to the different seasons.Methods: The Andalusian COPD audit was a pilot clinical project conducted from October 2013 to September 2014 in outpatient respiratory clinics of hospitals in Andalusia, Spain (8 provinces with more than 8 million inhabitants with retrospective data gathering. For the present analysis

  10. An agent-based model of cellular dynamics and circadian variability in human endotoxemia.

    Directory of Open Access Journals (Sweden)

    Tung T Nguyen

    Full Text Available As cellular variability and circadian rhythmicity play critical roles in immune and inflammatory responses, we present in this study an agent-based model of human endotoxemia to examine the interplay between circadian controls, cellular variability and stochastic dynamics of inflammatory cytokines. The model is qualitatively validated by its ability to reproduce circadian dynamics of inflammatory mediators and critical inflammatory responses after endotoxin administration in vivo. Novel computational concepts are proposed to characterize the cellular variability and synchronization of inflammatory cytokines in a population of heterogeneous leukocytes. Our results suggest that there is a decrease in cell-to-cell variability of inflammatory cytokines while their synchronization is increased after endotoxin challenge. Model parameters that are responsible for IκB production stimulated by NFκB activation and for the production of anti-inflammatory cytokines have large impacts on system behaviors. Additionally, examining time-dependent systemic responses revealed that the system is least vulnerable to endotoxin in the early morning and most vulnerable around midnight. Although much remains to be explored, proposed computational concepts and the model we have pioneered will provide important insights for future investigations and extensions, especially for single-cell studies to discover how cellular variability contributes to clinical implications.

  11. Drivers of Variability in Public-Supply Water Use Across the Contiguous United States

    Science.gov (United States)

    Worland, Scott C.; Steinschneider, Scott; Hornberger, George M.

    2018-03-01

    This study explores the relationship between municipal water use and an array of climate, economic, behavioral, and policy variables across the contiguous U.S. The relationship is explored using Bayesian-hierarchical regression models for over 2,500 counties, 18 covariates, and three higher-level grouping variables. Additionally, a second analysis is included for 83 cities where water price and water conservation policy information is available. A hierarchical model using the nine climate regions (product of National Oceanic and Atmospheric Administration) as the higher-level groups results in the best out-of-sample performance, as estimated by the Widely Available Information Criterion, compared to counties grouped by urban continuum classification or primary economic activity. The regression coefficients indicate that the controls on water use are not uniform across the nation: e.g., counties in the Northeast and Northwest climate regions are more sensitive to social variables, whereas counties in the Southwest and East North Central climate regions are more sensitive to environmental variables. For the national city-level model, it appears that arid cities with a high cost of living and relatively low water bills sell more water per customer, but as with the county-level model, the effect of each variable depends heavily on where a city is located.

  12. Effect of aquifer storage and recovery (ASR) on recovered stormwater quality variability.

    Science.gov (United States)

    Page, D W; Peeters, L; Vanderzalm, J; Barry, K; Gonzalez, D

    2017-06-15

    Aquifer Storage and Recovery (ASR) is increasingly being considered as a means of reusing urban stormwater to supplement available urban water resources. Storage of stormwater in an aquifer has been shown to affect water quality but it has also been claimed that storage will also decrease the stormwater quality variability making for improved predictability and management. This study is the first to document the changes in stormwater quality variability as a result of subsurface storage at four full scale ASR sites using advanced statistical techniques. New methods to examine water quality are required as data is often highly left censored and so traditional measures of variability such as the coefficient of variation are inappropriate. It was observed that for some water quality parameters (most notably E. coli) there was a marked improvement of water quality and a significant decrease in variability at all sites. This means that aquifer storage prior to engineered treatment systems may be advantageous in terms of system design to avoid over engineering. For other parameters such as metal(loids)s and nutrients the trend was less clear due to the numerous processes occurring during storage leading to an increase in variability, especially for geogenic metals and metalloids such as iron and arsenic. Depending upon the specific water quality parameters and end use, use of ASR may not have a dampening effect on stormwater quality variability. Crown Copyright © 2017. Published by Elsevier Ltd. All rights reserved.

  13. Variable temperature ion trap studies of CH4+ + H2, HD and D2: negative temperature dependence and significant isotope effect

    International Nuclear Information System (INIS)

    Asvany, O.; Savic, I.; Schlemmer, S.; Gerlich, D.

    2004-01-01

    Reactions of methane cations, CH 4 + , with H 2 , HD and D 2 have been studied in a variable temperature 22-pole ion trap from room temperature down to 15 K. The formation of CH 5 + in collisions with H 2 is slow at 300 K, but it becomes faster by at least one order of magnitude when the temperature is lowered to 15 K. This behavior is tentatively explained with a longer complex lifetime at low temperatures. However, since tunneling is most probably not responsible for product formation, other dynamical or statistical restrictions must be responsible for the negative temperature dependence. In collisions of CH 4 + with HD, the CH 5 + product ion (68% at 15 K) prevails over CH 4 D + (32%). Reaction of CH 4 + with D 2 is found to be much slower than with H 2 or HD. The rate coefficient for converting CH 4 + into CH 3 D + by H-D exchange has been determined to be smaller than 10 -12 cm 3 /s, indicating that scrambling in the CH 6 + complex is very unlikely

  14. A Longitudinal Study of Academic Progress Rate as a Result of Team and Institutional Variables at NCAA Division I Schools

    Science.gov (United States)

    Hale, Jimmie Edwin

    2014-01-01

    This study explained Academic Progress Rate (APR) levels and differences in APR (DAPR) with team and institutional variables. Team variables included team gender, sport profile, and squad size. Institutional variables included individual variables aggregated to the institutional level. The data analyzed in this study was derived from the National…

  15. Superflux chlorophyll-a analysis: An assessment of variability in results introduced prior to fluorometric analysis. [chesapeake bay and shelf regions

    Science.gov (United States)

    Cibik, S. J.; Rutledge, C. K.; Robertson, C. N.

    1981-01-01

    Several experiments were undertaken to identify variability in results that came from procedural differences in the processing of chlorophyll samples prior to fluorometric analysis. T-tests on group means indicated that significant differences (alpha = 0.05) in phaeopigment a concentrations did result in samples not initially screened, but not in the chlorophyll a concentrations. Highly significant differences (alpha = 0.001) in group means were found in samples which were held in acetone after filtering as compared to unfiltered seawater samples held for the same period. No difference in results was found between the 24-hour extraction and samples which were processed immediately.

  16. Dependence in probabilistic modeling Dempster-Shafer theory and probability bounds analysis

    Energy Technology Data Exchange (ETDEWEB)

    Ferson, Scott [Applied Biomathematics, Setauket, NY (United States); Nelsen, Roger B. [Lewis & Clark College, Portland OR (United States); Hajagos, Janos [Applied Biomathematics, Setauket, NY (United States); Berleant, Daniel J. [Iowa State Univ., Ames, IA (United States); Zhang, Jianzhong [Iowa State Univ., Ames, IA (United States); Tucker, W. Troy [Applied Biomathematics, Setauket, NY (United States); Ginzburg, Lev R. [Applied Biomathematics, Setauket, NY (United States); Oberkampf, William L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-05-01

    This report summarizes methods to incorporate information (or lack of information) about inter-variable dependence into risk assessments that use Dempster-Shafer theory or probability bounds analysis to address epistemic and aleatory uncertainty. The report reviews techniques for simulating correlated variates for a given correlation measure and dependence model, computation of bounds on distribution functions under a specified dependence model, formulation of parametric and empirical dependence models, and bounding approaches that can be used when information about the intervariable dependence is incomplete. The report also reviews several of the most pervasive and dangerous myths among risk analysts about dependence in probabilistic models.

  17. A particle method for history-dependent materials

    Energy Technology Data Exchange (ETDEWEB)

    Sulsky, D.; Chen, Z.; Schreyer, H.L. [New Mexico Univ., Albuquerque, NM (United States)

    1993-06-01

    A broad class of engineering problems including penetration, impact and large rotations of solid bodies causes severe numerical problems. For these problems, the constitutive equations are history dependent so material points must be followed; this is difficult to implement in an Eulerian scheme. On the other hand, purely Lagrangian methods typically result in severe mesh distortion and the consequence is ill conditioning of the element stiffness matrix leading to mesh lockup or entanglement. Remeshing prevents the lockup and tangling but then interpolation must be performed for history dependent variables, a process which can introduce errors. Proposed here is an extension of the particle-in-cell method in which particles are interpreted to be material points that are followed through the complete loading process. A fixed Eulerian grid provides the means for determining a spatial gradient. Because the grid can also be interpreted as an updated Lagrangian frame, the usual convection term in the acceleration associated with Eulerian formulations does not appear. With the use of maps between material points and the grid, the advantages of both Eulerian and Lagrangian schemes are utilized so that mesh tangling is avoided while material variables are tracked through the complete deformation history. Example solutions in two dimensions are given to illustrate the robustness of the proposed convection algorithm and to show that typical elastic behavior can be reproduced. Also, it is shown that impact with no slip is handled without any special algorithm for bodies governed by elasticity and strain hardening plasticity.

  18. Effect of specimen geometry on the variability in fatigue crack growth rate

    International Nuclear Information System (INIS)

    Tsuji, Hirokazu; Nakajima, Hajime; Kondo, Tatsuo

    1982-02-01

    Fatigue crack growth tests on SA 533 grade B class 1 steel were conducted in air with both contoured double cantilever beam (CDCB) specimens and compact-tension (CT) specimens for comparison, which corresponded to the ΔK constant and ΔK increasing fatigue tests respectively. The variability of the measured values was examined statistically, and possible sources of the determined variability were discussed. The variability in the ΔK increasing fatigue tests with the CT specimens was found to be substantially greater than that in the ΔK constant fatigue tests with the CDCB specimens employed in the present study. In addition, the width of the scatter as well as in the degree of deviation from the expected linearity in da/dN versus ΔK plots were found to be varied depending on the level of ΔK in the CT specimen. Based on the results, a conclusion was drawn that constant ΔK type tests should be preferred in the tests where accuracy and reproducibility of crack growth rate measurement was of particular importance. (author)

  19. Episiotomy and its relationship to various clinical variables that influence its performance

    Science.gov (United States)

    Ballesteros-Meseguer, Carmen; Carrillo-García, César; Meseguer-de-Pedro, Mariano; Canteras-Jordana, Manuel; Martínez-Roche, Mª Emilia

    2016-01-01

    Objective: to understand the episiotomy rate and its relationship with various clinical variables. Method: a descriptive, cross-sectional, analytic study of 12,093 births in a tertiary hospital. Variables: Parity, gestational age, start of labor, use of epidural analgesia, oxytocin usage, position during fetal explusion, weight of neonate, and completion of birth. The analysis was performed with SPSS 19.0. Results: the global percentage of episiotomies was 50%. The clinical variables that presented a significant association were primiparity (RR=2.98), gestational age >41 weeks (RR=1.2), augmented or induced labor (RR=1.33), epidural analgesia use (RR=1,95), oxytocin use (RR=1.58), lithotomy position during fetal expulsion (RR=6.4), and instrumentation (RR=1.84). Furthermore, maternal age ≥35 years (RR=0.85) and neonatal weight <2500 g (RR=0.8) were associated with a lower incidence of episiotomy. Conclusions: episiotomy is dependent on obstetric interventions performed during labor. If we wish to reduce the episiotomy rate, it will be necessary to bear in mind these risk factors when establishing policies for reducing this procedure. PMID:27224064

  20. Testing of variables which affect stablity of cement solidified low-level waste

    International Nuclear Information System (INIS)

    Boris, G.F.

    1989-01-01

    This paper describes the test program undertaken to investigate variables which could affect the stability of cement solidified low-level waste and to evaluate the effect of these variables on certain tests prescribed in the Technical Position on Waste Form. The majority of the testing was performed on solidified undepleted bead resin, however, six additional waste types, suggested by the NRC, were tested. The tested variables included waste loading, immersion duration, depletion level, ambient cure duration, curing environment, immersion medium and waste type. Of these, lower waste loadings, longer ambient cures prior to testing and immersion in demineralized water versus simulated sea water and potable water resulted in higher compressive strengths for bead resin samples. Immersion times longer than 90 days did not affect the resin samples. Compressive strengths for other waste types varied depending upon the waste. The strengths of all waste types exceeded the minimum criterion by at least a factor of four, up to a factor of forty. The higher waste loadings exhibit strengths less than the lower waste loadings