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Sample records for dependent pac studies

  1. Temperature dependent PAC studies with the rare earth '$^{172}$Lu' in ZnO

    CERN Document Server

    Nédélec, R

    2006-01-01

    Wide band-gap semiconductors have become an important base material for applications in optoelectronics and in high power, high temperature electronics. After doping with various rare earths, electroluminescence throughout the whole visible spectrum has been observed. We have studied the implantation behaviour of the rare earth Lu in ZnO. Our samples were implanted at the ISOLDE facility at CERN. In order to recover the sustained implantation damage the samples were treated in a rapid thermal annealing furnace. In a first attempt to measure the temperature dependence of the electric field gradient at the site of 172Lu/172Yb in ZnO a large jump in the quadrupole interaction frequency was observed between measurements at room temperature and 200 °C. Above 200 °C the frequency only changed very little. In order to understand this unusual behaviour we prepared another sample and studied the temperature range between room temperature and 200 °C in more detail. The results obtained previously could be confirmed....

  2. Defect Concentration Dependence of Inhomogeneous Broadening in PAC Spectroscopy

    Science.gov (United States)

    Adams, Mike; Bunker, Austin; Hodges, Jeffery; Park, Tyler; Stufflebeam, Michael; Evenson, William; Matheson, Phil; Zacate, Matthew

    2009-10-01

    Defects in crystals affect the electric field gradient (EFG) tensor components at radioactive probe nuclei. We consider the net EFG from a random distribution of vacancies combined with a single trapped vacancy in a near neighbor position. The net EFG perturbs angular correlation (PAC) and provides information about the concentration of vacancies. For various concentrations (.1 to 15 percent) we have simulated PAC spectra in simple cubic, body centered and face centered cubic crystal structures. Using the probability distributions we found for the EFG tensor components we reconstruct G2(t) for various defect concentrations. We take these reconstructions and compare them with the simulated G2(t) functions to check for self-consistency. We can then use the simulated probability distributions to examine the concentration dependence of experimental broadened PAC spectra. This work will be applied initially to broadened PAC data from β-Mn, Al-doped β-Mn, and Sr2RuO4.

  3. PAC study of silver chalcogenide superionic conductors

    International Nuclear Information System (INIS)

    Mekata, M.; Mizoh, Y.; Kyoto Univ.

    1981-01-01

    In order to study ionic motion in superionic conductors, PAC of 111 Cd was measured in Ag 2 S and Ag 2 Se. The observed ω 0 and eta reveal that probe ions occupy preferentially the tetrahedral sites. Static and dynamic interactions are found in the time spectra observed in the superionic phase and are interpreted in terms of dressed-ion and shake-off processes. The static component decreases with increasing temperature. Using the ratio of diffusion constants for Ag + and Cd ++ ions, the correlation time of Ag + ion is deduced. The activation energy is found to be about 12 kJ/mol. (orig.)

  4. Semiconductors with structurally determined vacancies PAC studies

    CERN Document Server

    Dietrich, M; Kortus, J; Unterricker, S; Deicher, M; Burchard, A; Magerle, R

    1999-01-01

    Ternary semiconductors of type Square Operator A/sup II/B/sub 2//sup III/C/sub 4//sup VI/ with an ordered array of vacancies were investigated by PAC. Thereby the six probes /sup 111m/Cd, /sup 117/Cd (/sup 117/In), /sup 111/In(/sup 111/Cd), /sup 111/Ag(/sup 111/Cd), /sup 77/Br(/sup 77/Se) and /sup 77/Kr(/sup 77/Br) were applied. The positions of the different probes are determined and the corresponding electric field gradients by the WIEN 95 code calculated. By /sup 111/Ag(/sup 111/Cd)-probes the vacancies could be substituted. The electronic charge density distributions are discussed. At elevated temperatures the substances show order- disorder transitions. As compared to the X-ray diffraction patterns the beginning of disorder is observed by PAC at distinctly lower temperatures. (7 refs).

  5. Study of Radiologic Technologists' Perceptions of Picture Archiving and Communication System (PACS) Competence and Educational Issues in Western Australia.

    Science.gov (United States)

    Floyd, Daniel M; Trepp, Errol R; Ipaki, Maryam; Ng, Curtise K C

    2015-06-01

    Although the implementation of picture archiving and communication system (PACS) could increase productivity of radiology departments, this depends on factors such as the PACS competence of radiologic technologists (RTs). The purpose of this study was to investigate the RTs' perceptions of PACS competence and educational issues in Western Australia (WA). A hardcopy questionnaire was distributed to WA RTs for obtaining their perceptions of PACS competence and educational issues. Descriptive (percentage of frequency, mean and standard deviation) and inferential statistics (t test and analysis of variance) were used to analyze the responses of the multiple choice and five-point scale questions from the returned questionnaires. The questionnaire response rate was 57.7% (173 out of 300). The mean values of all PACS competence questions except questions 2e-g are in the range of 3.9-4.9, i.e., around competent to very competent. Participants indicated they received adequate PACS training (mean 3.8). Statistically significant variables influencing RTs' perceptions of their PACS competence and educational issues including the age (p education received (p system, and received adequate training. However, future PACS education programs should be tailored to different RTs' groups. For example, multiple training modules might be necessary to support the PACS competence development of older RTs and those with lower general computer literacy.

  6. Pacific Tracker 2 - expert system (PacTrac2-ES) behavioural assessment and intervention tool for the Pacific Kids DASH for Health (PacDASH) study.

    Science.gov (United States)

    Novotny, Rachel; Nigg, Claudio; McGlone, Katalina; Renda, Gloria; Jung, Noah; Matsunaga, Masako; Karanja, Njeri

    2013-10-01

    The Pacific Tracker (PacTrac) is a computer program designed to analyse food intakes of individuals from the Pacific Region. PacTrac's original output included servings of daily intake of food groups according to the United States Food Guide Pyramid, nutrient intake recommendations, and a comparison to other national nutrition recommendations. PacTrac was made available for public use through the Hawaii Foods website (hawaiifoods.hawaii.edu). PacTrac2 is an updated and expanded version of PacTrac that uses the United States MyPyramid/MyPlate food groups in household units of daily intake, rather than servings. In addition, the PacTrac2 includes a physical activity analysis tool which quantifies minutes of physical activities and their intensities based on energy estimates from the compendium of physical activity and research on children. An Expert System (ES) - a computerised decision tree to guide behaviour change - was developed using information on self-efficacy and stage of readiness to change, and the fruit and vegetable intake and physical activity information from PacTrac2. The ES produces reports for the child, the parent/guardian, and the child's physician with child-specific strategies, targeted behavioural information, and feedback tailored to the child. PacTrac2-ES was designed for the Pacific Kids DASH for Health (PacDASH) intervention study, conducted in the Kaiser Permanente health care system in Hawaii. The intervention is based on the child's self-efficacy and stage of readiness to change intake of fruits and vegetables and physical activity, with a goal of maintaining body weight to prevent obesity. The intervention is complemented with stage-based mailers addressing the environment for physical activity and fruit and vegetable intake and newsletters that address related behaviours (sedentary activity and a DASH eating approach). This project is the first to expand the PacTrac to contain children's foods and physical activities from the Pacific

  7. PAC study of ionic motion in silver compound superionic conductors

    International Nuclear Information System (INIS)

    Mekata, M.; Seguchi, Y.

    1983-01-01

    Ionic motion in superionic conductors, Ag 2 S, Ag 2 Se and Ag 3 SI was investigated by γ-γ PAC on 111 Cd. Diffusion constant measurements showed that probe ions migrate almost as fast as Ag + ions above 500 K in Ag 2 S and Ag 2 Se and above 700 K in Ag 3 SI. Multivalent impurities were found to be unstable in AgI and Ag 2 Te. The correlation time of ionic motion was deduced from the observed relaxation rate together with the diffusion constants. The correlation time and its activation energy increase in order of Ag 2 S, Ag 2 Se and Ag 3 SI. The flight distance of Ag + ions remains almost constant in the measured temperature range. (Auth.)

  8. Comparison of a PACS workstation with conventional film for interpretation of neonatal examinations: A paired comparison study

    International Nuclear Information System (INIS)

    Franken, E.A. Jr.; Smith, W.L.; Berbaum, K.S.; Kao, S.C.S.; Sato, Y.

    1991-01-01

    The diagnostic value of neonatal examinations using picture archiving and communication systems (PACS) was compared with that of conventional radiographs. A total of 202 consecutive chest or abdominal radiographs from the newborn intensive care unit were digitized for display on a commercially available PACS console. Experimental design was a paired comparison study. Plain films and PACS images were reviewed alternately in unbiased fashion. After the examination was evaluated using the second modality, any change in diagnosis or confidence in diagnosis was noted. Overall evaluation showed slight preference for the PACS modality. Change of diagnosis or in confidence of diagnosis was more than twice as likely to occur with evaluation of PACS (35%) after hardcopy than with evaluation of conventional radiographs (14%) after PACS. Of the variety of image processing features available on PACS, only window and leveling were judged to be of significant value. These results indicate that PACS and conventional radiographs of the neonatal chest and abdomen are of similar diagnostic value. (orig.)

  9. Study of hyperfine parameters in Co-doped tin dioxide using PAC spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Ramos, Juliana M.; Carbonari, Artur W.; Martucci, Thiago; Costa, Messias S.; Saxena, Rajendra N. [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil); Vianden, R.; Kessler, P.; Geruschke, T.; Steffens, M., E-mail: vianden@hiskp.uni-bonn.d [Rheinische Friedrich-Wilhelms-Universitaet Bonn (HISKP- Bonn) (Germany). Helmholtz - Institut fuer Strahlen- und Kernphysik

    2011-07-01

    PAC technique has been used to measure the hyperfine interactions in nano-structured powder samples of semiconducting SnO{sub 2} doped with Co. The aim of this work is to compare the results of PAC measurements using two different techniques of introducing the radioactive {sup 111}In probe nuclei in the sample of SnO{sub 2} doped with Co. The perturbed gamma-gamma angular correlation (PAC) spectroscopy is used for the measurements of the magnetic hyperfine field (MHF) and the electric field gradient (EFG) at {sup 111}Cd sites in SnO{sub 2} doped with 1% and 2% Co. The measurement of EFG is used to study the defects introduced in the semiconductor material and also for the identification of different phases formed within the compound. The techniques utilized for introducing the radioactive {sup 111}In in the sample are the ion-implantation using radioactive ion beam of {sup 111}In and the chemical process in which {sup 111}InCl{sub 3} solution is added during the preparation of SnO{sub 2} doped with Co using sol gel method. The ion-implantation of {sup 111}In in SnO{sub 2} doped with Co was carried out using the University of Bonn ion-implanter with beam energy of 160 keV. The PAC measurements were carried out with four BaF{sub 2} detector gamma spectrometer in the temperature range of 10-295 K. The results show no significant difference in the values of hyperfine parameters. Both techniques show practically the same electric quadrupole interaction for the substitutional site. The results were compared with previous PAC and Moessbauer measurements of SnO{sub 2} powder samples using {sup 111}In-{sup 111}Cd probe. (author)

  10. Rare earths in GaN and ZnO studied with the PAC method

    International Nuclear Information System (INIS)

    Nedelec, R.

    2007-01-01

    The present thesis deals with the implantation and annealing behaviour of two examples of large-band-gap semiconductors GaN and ZnO. The studies begin with the annealing behaviour of GaN after the implantation of 172 Lu. For GaN the annealing process begins at low temperatures with the decreasing of the damping of the lattice frequency. At essentially higher temperatures finally the substitunial contribution increases. This behaviour is also observed for other probe nuclei in GaN. For ZnO the behaviour at low temperature is different. Both for 172 Lu and for 181 Hf the damping is already after the implantation very low. The increasement of the substitutional contribution occurs like in GaN at higher temperatures. Thereafter for GaN and ZnO PAC spectra were token up at different measurement temperatures between 25 and 873 K. For 172 Lu in GaN and in ZnO a strong temperature dependence of the lattice field gradient was observed. Also for 181 Hf in ZnO a strong temperature dependence is observed. For 172 Lu by means of a model for the interaction of quadrupole moments of electronic shells with the nucleus a lattice field gradient of ±5.9.10 15 Vcm -2 could be determined. For 172 Lu in ZnO the model yields at 293 K a lattice field gradient of +14.10 15 Vcm -2 respectively -13.10 15 Vcm -2 . The corrsponding measurement with 181 Hf yields a lattice field gradient of ±5.7.10 15 Vcm -2

  11. 111Cd PAC Study of Gd-Ni Intermetallic Compounds

    International Nuclear Information System (INIS)

    Presa, P. de la; Forker, M.

    2004-01-01

    This paper presents a perturbed angular correlation study of the magnetic and electric hyperfine interactions of 111 Cd on Gd sites of the Gd-Ni intermetallic compounds GdNi, GdNi 2 , GdNi 3 , Gd 2 Ni 7 , GdNi 5 and Gd 2 Ni 17 .

  12. tRNA-dependent peptide bond formation by the transferase PacB in biosynthesis of the pacidamycin group of pentapeptidyl nucleoside antibiotics.

    Science.gov (United States)

    Zhang, Wenjun; Ntai, Ioanna; Kelleher, Neil L; Walsh, Christopher T

    2011-07-26

    Pacidamycins are a family of uridyl tetra/pentapeptide antibiotics with antipseudomonal activities through inhibition of the translocase MraY in bacterial cell wall assembly. The biosynthetic gene cluster for pacidamycins has recently been identified through genome mining of the producer Streptomyces coeruleorubidus, and the highly dissociated nonribosomal peptide assembly line for the uridyl tetrapeptide scaffold of pacidamycin has been characterized. In this work a hypothetical protein PacB, conserved in known uridyl peptide antibiotics gene clusters, has been characterized by both genetic deletion and enzymatic analysis of the purified protein. PacB catalyzes the transfer of the alanyl residue from alanyl-tRNA to the N terminus of the tetrapeptide intermediate yielding a pentapeptide on the thio-templated nonribosomal peptide synthetase (NRPS) assembly line protein PacH. PacB thus represents a new group of tRNA-dependent peptide bond-forming enzymes in secondary metabolite biosynthesis in addition to the recently identified cyclodipeptide synthases. The characterization of PacB completes the assembly line reconstitution of pacidamycin pentapeptide antibiotic scaffolds, bridging the primary and secondary metabolic pathways by hijacking an aminoacyl-tRNA to the antibiotic biosynthetic pathway.

  13. Study of molybdenum oxide by means of Perturbed Angular Correlations (PAC) and Mössbauer spectroscopy

    CERN Multimedia

    Among transition-metal oxides, the molybdenum oxide compounds are particularly attractive due to the structural (2D) anisotropy and to the ability of the molybdenum ion to change its oxidation state. These properties make it suitable for applications on, e.g., chemical sensors, solar cells, catalytic and optoelectronic devices. At ISOLDE we aim studying the incorporation of selected dopants by ion implantation, using the nuclear techniques of Perturbed Angular Correlations (PAC) and Mössbauer spectroscopy (MS). Both techniques make use of highly diluted radioactive probe nuclei, which interact – as atomic-sized tips – with the host atoms and defects. The objectives of this project are to study at the atomic scale the probe’s local environment, its electronic configuration and polarization, the probe’s lattice sites, point defects and its recombination dynamics. In the case of e-$\\gamma$ PAC, the electron mobility on the host can be further studied, e.g., as a function of temperature.

  14. Vendor neutral archive in PACS.

    Science.gov (United States)

    Agarwal, Tapesh Kumar; Sanjeev

    2012-10-01

    An archive is a location containing a collection of records, documents, or other materials of historical importance. An integral part of Picture Archiving and Communication System (PACS) is archiving. When a hospital needs to migrate a PACS vendor, the complete earlier data need to be migrated in the format of the newly procured PACS. It is both time and money consuming. To address this issue, the new concept of vendor neutral archive (VNA) has emerged. A VNA simply decouples the PACS and workstations at the archival layer. This is achieved by developing an application engine that receives, integrates, and transmits the data using the different syntax of a Digital Imaging and Communication in Medicine (DICOM) format. Transferring the data belonging to the old PACS to a new one is performed by a process called migration of data. In VNA, a number of different data migration techniques are available to facilitate transfer from the old PACS to the new one, the choice depending on the speed of migration and the importance of data. The techniques include simple DICOM migration, prefetch-based DICOM migration, medium migration, and the expensive non-DICOM migration. "Vendor neutral" may not be a suitable term, and "architecture neutral," "PACS neutral," "content neutral," or "third-party neutral" are probably better and preferred terms. Notwithstanding this, the VNA acronym has come to stay in both the medical IT user terminology and in vendor nomenclature, and radiologists need to be aware of its impact in PACS across the globe.

  15. Vendor neutral archive in PACS

    Directory of Open Access Journals (Sweden)

    Tapesh Kumar Agarwal

    2012-01-01

    Full Text Available An archive is a location containing a collection of records, documents, or other materials of historical importance. An integral part of Picture Archiving and Communication System (PACS is archiving. When a hospital needs to migrate a PACS vendor, the complete earlier data need to be migrated in the format of the newly procured PACS. It is both time and money consuming. To address this issue, the new concept of vendor neutral archive (VNA has emerged. A VNA simply decouples the PACS and workstations at the archival layer. This is achieved by developing an application engine that receives, integrates, and transmits the data using the different syntax of a Digital Imaging and Communication in Medicine (DICOM format. Transferring the data belonging to the old PACS to a new one is performed by a process called migration of data. In VNA, a number of different data migration techniques are available to facilitate transfer from the old PACS to the new one, the choice depending on the speed of migration and the importance of data. The techniques include simple DICOM migration, prefetch-based DICOM migration, medium migration, and the expensive non-DICOM migration. "Vendor neutral" may not be a suitable term, and "architecture neutral," "PACS neutral," "content neutral," or "third-party neutral" are probably better and preferred terms. Notwithstanding this, the VNA acronym has come to stay in both the medical IT user terminology and in vendor nomenclature, and radiologists need to be aware of its impact in PACS across the globe.

  16. Increase in productivity by implementation of RIS and PACS throughout a clinic: a case study

    International Nuclear Information System (INIS)

    Nissen-Meyer, S.; Holzknecht, N.; Wieser, B.; Francke, M.; Kuettner, B.; Weber, J.; Reiser, M.; Adelhard, K.; Villain, S.

    2002-01-01

    Problem. How are improvements in productivity in connection with RIS/PACS to be defined? What do they cost? To limit the problem to the relevant topics, we first describe the objectives of a radiology department and the identified bottlenecks in the workflow. How to define and assess the improvements is discussed.Methods. The case in question for this study is the RIS/PACS project at the ''Klinikum der Universitaet Muenchen, Campus Grosshadern''. The goals of the project and its present status are reviewed. The project is not yet completed, so this is a ''midterm'' report.Results and discussion. We describe the status of the achieved and not yet achieved goals and of the eliminated bottlenecks. On the plus side, for example, nearly 100% of all digitally generated images (except mammogramms) are digitally archived. They are accessible to the same percentage in radiology via PACS and in the hospital via the webbased intranet image distribution system when needed. In some radiology areas, such as multislice CT, already the reporting can no longer be performed without softcopy image interpretation. However, the full elimination of hardcopy images is still not reality, since the distribution to DICOM viewers for selected requesters with demands for almost reporting quality, high cost image displays is still in the testphase. To reduce film costs, images are being printed on a high resolution paper printer in addition to the intranet distribution during this transition period. On the negative side, due to a lack of job positions in the transcription rooms, about 40% of the reports are still being handwritten by radiologists. Furthermore, the dictated and transcribed reports are usually still not available early enough in the RIS and thereby in the intranet report distribution of the hospital. Here only a speech recognition system can remedy the situation. As soon as this problem is solved and the image distribution to the DICOM viewers works routinely, the reports and

  17. PACS and its hospital-wide implementation: A case study at the Madigan Army Medical Center

    International Nuclear Information System (INIS)

    Choi, Hyung Sik; Kim, Yong Min; Smith, Donald V.; Bender, Gregory N.

    1993-01-01

    PACS represents the future of radiology in modern hospitals. Workstations and databases can be developed to substantially increase clinician's productivity, improve diagnostic accuracy, and make a large amount of knowledge and patient information available on-line to the physician. Currently, there are several hospitals in the process of implementing a total PACS system. They include Madigan Army Medical Center (Tacoma, Washington), VA Hospital in Baltimore, and Hammersmith Hospital in London (1). In order to provide the radiologist, the clinicians, and other health personnel in Korea with the general concept of PACS and its up-to-date status report, we describe the MDIS system being implemented in MAMC (Madigan Army Medical Center) which is the first hospital-wide large-scale PACS in the world. The major PACS components in MAMC have been installed since March 1992 and the full system implementation will be completed by summer 1993. The goal of the MDIS system in MAMC is to increase to more than 90% filmless by the end of 1993. In this paper, we discuss the introduction and background of PACS and its potential benefits, the current status of PACS installation in MAMC and the future plan, and the flow of image data and text information in MAMC

  18. Current status and installation of dental PACS

    International Nuclear Information System (INIS)

    Park, Chang Seo; Kim, Kee Deog; Park, Hyok; Jeong, Ho Gul

    2004-01-01

    Picture Archiving and Communication System (PACS) is difficult to implement in the best of situations, but evidence is growing that the benefits are significant. The aims of this study are to analyze the current status of full PACS and establish successful installation standard of dental PACS. Materials and Methods were based on the investigation of current working status and installation standard of PACS, and observation of variable issues to installation of dental PACS. By September 30, 2004, full PACS implementations in their facilities were 88.1% in specialized general hospitals (37 installations out of total 42 hospitals), 59.8% in general hospitals (144 installations out of total 241 hospitals), 12.3% in medical hospitals (116 installations out of total 941 hospitals) and 3.6% in dental hospitals (4 installations out of total 110 hospitals). Only 4 university dental hospitals currently have installed and are operating full PACS. Major obstacle to wide spread of dental PACS is initial high investments. Clinical environments of dental PACS differed from medical situation. Because of characteristic dental practice, the initial investments for dental PACS are generally much greater than those of medical PACS. Also new economic crisis makes users scruple. The best way to overcome these limitations is to establish an economic installation standard for dental PACS. Also the clear technical communication between the customer and the supplier before both sides are committed to the obstacles are critical to its success.

  19. dicomPACS: PACS Leader in Germany - Kodak Partner

    OpenAIRE

    Maziyar Shakeri

    2007-01-01

    History of Distributor: We are PDP Co. (Pardazesh Danesh Pezeshki) founded in 1998 with more than 8 years Experiments in Diagnostic Medical Imaging Market .we launched our New Division in 2002 for Digital Imaging and Softcopy under name of PDP View . We studied our market demands and PACS Provider Companies for 2 years and finally we signed the Contract with the first leader German PACS Provider named dicomPACS ® ."nWe are the only company who their 3 engineers well trained in th...

  20. PAC studies of implanted $^{111}\\!$Ag in single-crystalline ZnO

    CERN Document Server

    Rita, E; Wahl, Ulrich; Alves, E; Lima-Lopes, Armandina Maria; Carvalho-Soares, João

    2005-01-01

    The local environment of implanted $^{111}\\!$Ag ( t$_{1/2}$=7.45d ) in single-crystalline [0001] ZnO was evaluated by means of the perturbed angular correlation (PAC) technique. Following the 60 keV low dose ($1\\!\\times\\!10^{13}$ cm$^{-2}$) $^{111}\\!$Ag implantation, the PAC measurements were performed for the as-implanted state and following 30 min in vacuum annealing steps, at temperatures ranging from 200 ºC to 1050 ºC. The results revealed that 42% of the probes are located at defect-free S$\\scriptstyle_\\textrm{Zn}$ sites ($\

  1. First Results Of The Diagnostic Evaluation Studies And The Clinical Efficacy Evaluation In The Dutch PACS Project

    Science.gov (United States)

    Barneveld Binkhuysen, F. H.; Ottes, F. P.; ter Haar Romeny, B. M.; Klessens, P. L. M.; Vos, C. G.; Winter, L. H. L.; Calkoen, P. T.; Andriessen, J. H. T. H.

    1989-05-01

    The objective of the studies was to evaluate the diagnostic performance of the image digitizing distribution and display equipment of the installed PACS (Philips) in the Utrecht University Hospital (see also procee-dings SPIE 914, 1988). The diagnostic accuracy was evaluated by means of observer performance studies, using ROC analysis. Three series of films were used: chest phantom radiographs, clinical mammographic films, and clinical head CT's. We compared: original films versus images digitized with a video scanner, and/or original films versus images digitized with a laser scanner. Both scanners have 1024x1024x8 bits output resolution. Four radiologists scored the presence on a 5-point scale. The results of the mammographic and head CT series will be presented in this paper. The results of the diagnostic accuracy studies of the chest radiographs and their specific methodology will be presented in a companion SPIE paper. Goal of the clinical efficacy study is to see if the use of a PACS multimodality viewing station at an internal ward has clinical advantages as compared to the conventional situation. Using PACS integrated with a HIS (including a RIS) more easier and faster information is accessible to the clinicians. In this paper we will describe: the procedures which are needed to evaluate the use of the workstation installed at the internal ward, the development of the user interface with four layers of the Image Management System, and the methodology of evaluation the clinical advantages.

  2. Vendor neutral archive in PACS

    International Nuclear Information System (INIS)

    Agarwal, Tapesh Kumar; Sanjeev

    2012-01-01

    An archive is a location containing a collection of records, documents, or other materials of historical importance. An integral part of Picture Archiving and Communication System (PACS) is archiving. When a hospital needs to migrate a PACS vendor, the complete earlier data need to be migrated in the format of the newly procured PACS. It is both time and money consuming. To address this issue, the new concept of vendor neutral archive (VNA) has emerged. A VNA simply decouples the PACS and workstations at the archival layer. This is achieved by developing an application engine that receives, integrates, and transmits the data using the different syntax of a Digital Imaging and Communication in Medicine (DICOM) format. Transferring the data belonging to the old PACS to a new one is performed by a process called migration of data. In VNA, a number of different data migration techniques are available to facilitate transfer from the old PACS to the new one, the choice depending on the speed of migration and the importance of data. The techniques include simple DICOM migration, prefetch-based DICOM migration, medium migration, and the expensive non-DICOM migration. “Vendor neutral” may not be a suitable term, and “architecture neutral,” “PACS neutral,” “content neutral,” or “third-party neutral” are probably better and preferred terms. Notwithstanding this, the VNA acronym has come to stay in both the medical IT user terminology and in vendor nomenclature, and radiologists need to be aware of its impact in PACS across the globe

  3. Programa de Aceleração do Crescimento (PAC: um estudo descritivo sobre os desperdícios ativos e passivos = Growth Acceleration Program (PAC: a descriptive study of active and passive waste

    Directory of Open Access Journals (Sweden)

    Daniele Silva Rodrigues

    2018-03-01

    water resources. This program, in its first phase (2007-2010, contributed in a decisive way to the increase in the supply of jobs and in the generation of income in Brazil. However, according to "Instituto Trata Brasil" 86% of the sanitary sewage works from the PAC were paralyzed, or delayed or not started until December 2012. Also, in 2008 and 2009, through the special edition of the Inspection Program by Public Sweepstakes, the Federal Comptroller General's Office found several irregularities in 110 Brazilian municipalities covered with PAC funds. In this context, the objective of the study was to analyze the irregularities verified by the CGU, in the application of the federal resources destined to the sanitation and housing areas of the Brazilian municipalities through the first stage of the PAC. The main source of data for the survey were CGU's reports from the PAC and Census 2000 data, made available by IBGE. The techniques of Content analysis were used to classify the irregularities, verified by the CGU, in active waste (corruption and passive (mismanagement. The Descriptive statistics were used to analyze the profile of irregularities and the municipalities audited. It was observed that the most frequent wastes in the municipalities audited are those classified as Overbilling and Fraudulent Bidding (classified as active waste; and “Bad Administration” and “Irregular Bidding”, in the form of passive waste.

  4. Factors Associated with Anxiety in Premature Coronary Artery Disease Patients: THC-PAC Study

    Directory of Open Access Journals (Sweden)

    Seyed Hesameddin Abbasi

    2016-05-01

    Full Text Available Anxiety may negatively affect the course of coronary artery disease (CAD. The aim of this study was to assess which factors are associated with anxiety in young adults with CAD. A cohort of individuals with premature coronary artery disease was formed between 2004-2011, as the Tehran Heart Center's Premature Coronary Atherosclerosis Cohort (THC-PAC study. Patients (men≤45-year-old, and women≤55-year-old were visited between March 2013 and February 2014. All participants were examined, and their demographic, clinical, and laboratory data were collected. Then, all participants filled in the Beck Anxiety Inventory. Logistic regression models were used to identifying factors related to anxiety in both sexes. During the study, 708 patients (mean [SD] age: 45.3 [5.8] y, men:48.2% were visited. Anxiety was present in 53.0% of participants (66.0% of women and 39.0% of men. The logistic regressions model showed that the associated factors for anxiety in men were opium usage (OR=1.89, 95% CI: 1.09-3.27, positive family history (OR=1.49, 95% CI:0.94-2.35, and creatinine serum level (OR=1.17, 95% CI:1.05-1.303; and in women were major adverse cardiac events (MACE during follow-up (OR=2.30, 95% CI:1.25-4.23, hypertension (OR=1.71, 95% CI:1.07-2.73 and the duration of CAD (OR=0.99, 95% CI:0.98-1.00. In premature CAD patients, the determinants of anxiety seem to be different in each sex. Opium usage, positive family history of CAD, and creatinine serum levels in men, and MACE, hypertension, and duration of CAD in women appear the relevant factors in this regard.

  5. Experimental Study of RailPAc Plasma Actuator for High-Authority Aerodynamic Flow Control in One Atmosphere

    Science.gov (United States)

    Gray, Miles; Choi, Young-Joon; Raja, Laxminarayan; Sirohi, Jayant

    2014-10-01

    Dielectric barrier discharge (DBD) actuators, a type of electrohydrodynamic (EHD) plasma actuator, have generated considerable interest in recent years. However, theoretical performance limitations hinder their application for high speed flows. Magnetohydrodynamic (MHD) plasma actuators with higher control authority circumvent these limitations, offering an excellent alternative. The rail plasma actuator (RailPAc) is an MHD actuator which uses Lorentz force to impart momentum to the surrounding air. RailPAc functions by generating a fast propagating arc column between two rail electrodes that accelerate the arc through J × B forces in a self-induced B-field. The arc column drags the surrounding air to induce aerodynamic flow motion. Our study of the RailPAc will include a description of the transient arc discharge structure through high-speed imaging and a description of the arc composition and temperature through time-resolved emission spectroscopy. Time-resolved force measurements quantify momentum transfer from the arc to the surrounding air and provides a direct measure of the actuator control authority.

  6. PACS in nuclear medicine

    International Nuclear Information System (INIS)

    Kang, Keon Wook

    2000-01-01

    PACS (Picture Archiving and Communication System) is being rapidly spread and installed in many hospitals, but most of the system do not include nuclear medicine field. Although additional costs of hardware for nuclear medicine PACS is low, the complexity in developing viewing software and little market have made the nuclear medicine PACS not popular. Most PACS utilize DICOM 3.0 as standard format, but standard format in nuclear medicine has been Interfile. Interfile should be converted into DICOM format if nuclear images are to be stored and visualized in most PACS. Nowadays, many vendors supply the DICOM option in gamma camera and PET. Several hospitals in Korea have already installed nucler PACS with DICOM, but only the screen captured images are supplied. Software for visualizing pseudo-color with color lookup tables and expressing with volume view should be developed to fulfill the demand of referring physicians and nuclear medicine physicians. PACS is going to integrate not only radiologic images but also endoscopic and pathologic images. Web and PC based PACS is now a trend and is much compatible with nuclear medicine PACS. Most important barrier for nuclear medicine PACS that we encounter is not a technical problem, but indifference of investor such as administrator of hospital or PACS. Now it is time to support and invest for the development of nuclear medicine PACS

  7. Rare earths in GaN and ZnO studied with the PAC method; Seltene Erden in GaN und ZnO untersucht mit der PAC-Methode

    Energy Technology Data Exchange (ETDEWEB)

    Nedelec, R.

    2007-07-01

    The present thesis deals with the implantation and annealing behaviour of two examples of large-band-gap semiconductors GaN and ZnO. The studies begin with the annealing behaviour of GaN after the implantation of {sup 172}Lu. For GaN the annealing process begins at low temperatures with the decreasing of the damping of the lattice frequency. At essentially higher temperatures finally the substitunial contribution increases. This behaviour is also observed for other probe nuclei in GaN. For ZnO the behaviour at low temperature is different. Both for {sup 172}Lu and for {sup 181}Hf the damping is already after the implantation very low. The increasement of the substitutional contribution occurs like in GaN at higher temperatures. Thereafter for GaN and ZnO PAC spectra were token up at different measurement temperatures between 25 and 873 K. For {sup 172}Lu in GaN and in ZnO a strong temperature dependence of the lattice field gradient was observed. Also for {sup 181}Hf in ZnO a strong temperature dependence is observed. For {sup 172}Lu by means of a model for the interaction of quadrupole moments of electronic shells with the nucleus a lattice field gradient of {+-}5.9.10{sup 15} Vcm{sup -2} could be determined. For {sup 172}Lu in ZnO the model yields at 293 K a lattice field gradient of +14.10{sup 15} Vcm{sup -2} respectively -13.10{sup 15} Vcm{sup -2}. The corrsponding measurement with {sup 181}Hf yields a lattice field gradient of {+-}5.7.10{sup 15} Vcm{sup -2}.

  8. PAC Experiments at ISOLDE

    CERN Multimedia

    2002-01-01

    The study of hyperfine interactions offers the possibility to use radioactive nuclei as probes in matter. The @g-@g perturbated angular correlation (PAC) technique following implantation has found widespread application in this field. At ISOLDE we have been investigating electric field gradients at impurities in non-cubic metals in an ongoing series of experiments. \\\\ \\\\ The small number of probe atoms necessary for these measurements make them also ideally suited for studies of surface problems like diffusion, structure and dynamics. Cd on a molybdenum O110? surface will be studied as first system. For this purpose 10|1|0~atoms of |1|1|1|mCd will be evaporated onto the clean surface and the electric field gradient for isolated adatoms on terrace sites will be determined by PAC. The UHV system constructed for such experiments at ISOLDE is shown in the schematic drawing. It is coupled to the beam line through differential pumping stations and contains standard surface treatment and analysis equipment.

  9. HIS-PACS Coupling In Practice

    Science.gov (United States)

    Lodder, Herman; van Poppel, Bas M.; J. de Valk, Jan P.; Wilmink, Hans B. M.; Ising, Carola; Bakker, Ab R.

    1989-05-01

    The existence of a link between a HIS, incorporating a RIS, and a PACS is one of the most indispensible prerequisites to perform a clinical evaluation study of a PACS in practice. The two main reasons for realizing a IIIS-PACS coupling are concerned with 1) proper image management e.g. in order to achieve acceptable waiting times and 2) the user need of having all patient relevant data available in the same workstation. A first phase coupling between an existing HIS and a just installed PACS has been realized by BAZIS in the Utrecht University Hospital in the Netherlands. These activities were carried out as part of the Dutch PACS Project, a collaboration in the PACS field of BAZIS, the Utrecht University Hospital (AZU) and Philips Medical Systems. For the first phase only HIS data of the in-patients of one particular ward of Internal Medicine were transmitted using a one-way dataflow (from. HIS to PACS). In phase two the coupling will he hi-directional and more departments will be part of the experiment. In phase three of the coupling project a more general. HIS-PACS interface will be developed, independent of the HIS and PACS manufacturers. In April 1988 the first public data exchange (patient data, order data, reports) between the BAZIS/ZIS and Philips/MARCOM system has been demonstrated. This was the first working example of a HIS-PACS coupling worldwide to our knowledge. This paper gives an overview of the experimental set-up, the demonstration during the 6th EuroPACS meeting , the results and problems encountered thusfar and statistical data from daily practice.

  10. PACS influence the radiographer's work

    International Nuclear Information System (INIS)

    Fridell, Kent; Aspelin, Peter; Edgren, Lars; Lindskoeld, Lars; Lundberg, Nina

    2009-01-01

    Radiological departments are changing rapidly due to the implementation of digital images and PACS (Picture Archiving and Communication Systems). The introduction of new technology seems to dissolve boundaries between the professions in the work environment where the technology is introduced. This process tends to change the organization and its routines. The aim of this qualitative study is to explore changes in radiographers' work with regard to skills, work practice and technology. The study used open-ended interviews to explore the radiographers' perceptions of such changes, and to identify problems and solutions pertaining to work practice. Inspiration is taken from grounded theory to explain the changes in work that were found. Respondents were selected from a total of 133 potential participants as a theoretical or purposive sample. The changing trends within the professional role indicated that radiographers, as image producers, shifted their focus from the ability to set the optimal exposure parameters in order to obtain the optimal image for diagnosis to become expert in exposure parameters, projection techniques and diagnostic practice, having multifaceted skills, as being the jack of all trades. When implementing PACS there was an obvious change in image production. At the start there were visions of new routines, and therefore the radiographers became early adopters to the new technology; in practice the organization was stacked in old routines, as the routines were inflexible and PACS work was pushed into old work routines. Although inflexible, this does not mean that they cannot change, and obviously in 2006 new routines had been implemented making it possible for the radiographers in finding new ways for collaborating with colleagues. The new technology immediately created a vision of improved service to the clinicians. In order to optimize the service the radiographers developed an insight into the need for a more comprehensive change in work using

  11. The future of PACS

    International Nuclear Information System (INIS)

    Nagy, Paul G.

    2007-01-01

    How will the future of picture archiving and communication systems (PACS) look, and how will this future affect the practice of radiology? We are currently experiencing disruptive innovations that will force an architectural redesign, making the majority of today’s commercial PACS obsolete as the field matures and expands to include imaging throughout the medical enterprise. The common architecture used for PACS cannot handle the massive amounts of data being generated by even current versions of computed tomography and magnetic resonance scanners. If a PACS cannot handle today’s technology, what will happen as the field expands to encompass pathology imaging, cone-beam reconstruction, and multispectral imaging? The ability of these new technologies to enhance research and clinical care will be impaired if PACS architectures are not prepared to support them. In attempting a structured approach to predictions about the future of PACS, we offer projections about the technologies underlying PACS as well as the evolution of standards development and the changing needs of a broad range of medical imaging. Simplified models of the history of the PACS industry are mined for the assumptions they provide about future innovations and trends. The physicist frequently participates in or directs technical assessments for medical equipment, and many physicists have extended these activities to include imaging informatics. It is hoped that by applying these speculative but experienced-based predictions, the interested medical physicist will be better able to take the lead in setting information technology strategies that will help facilities not only prepare for the future but continue to enjoy the benefits of technological innovations without disruptive, expensive, and unexpected changes in architecture. A good PACS strategy can help accelerate the time required for innovations to go from the drawing board to clinical implementation.

  12. The future of PACS

    Energy Technology Data Exchange (ETDEWEB)

    Nagy, Paul G. [Department of Diagnostic Radiology, University of Maryland School of Medicine, 22 South Greene Street, Baltimore, Maryland 21201 (United States)

    2007-07-15

    How will the future of picture archiving and communication systems (PACS) look, and how will this future affect the practice of radiology? We are currently experiencing disruptive innovations that will force an architectural redesign, making the majority of today’s commercial PACS obsolete as the field matures and expands to include imaging throughout the medical enterprise. The common architecture used for PACS cannot handle the massive amounts of data being generated by even current versions of computed tomography and magnetic resonance scanners. If a PACS cannot handle today’s technology, what will happen as the field expands to encompass pathology imaging, cone-beam reconstruction, and multispectral imaging? The ability of these new technologies to enhance research and clinical care will be impaired if PACS architectures are not prepared to support them. In attempting a structured approach to predictions about the future of PACS, we offer projections about the technologies underlying PACS as well as the evolution of standards development and the changing needs of a broad range of medical imaging. Simplified models of the history of the PACS industry are mined for the assumptions they provide about future innovations and trends. The physicist frequently participates in or directs technical assessments for medical equipment, and many physicists have extended these activities to include imaging informatics. It is hoped that by applying these speculative but experienced-based predictions, the interested medical physicist will be better able to take the lead in setting information technology strategies that will help facilities not only prepare for the future but continue to enjoy the benefits of technological innovations without disruptive, expensive, and unexpected changes in architecture. A good PACS strategy can help accelerate the time required for innovations to go from the drawing board to clinical implementation.

  13. Making the PACS workstation a browser of image processing software: a feasibility study using inter-process communication techniques.

    Science.gov (United States)

    Wang, Chunliang; Ritter, Felix; Smedby, Orjan

    2010-07-01

    To enhance the functional expandability of a picture archiving and communication systems (PACS) workstation and to facilitate the integration of third-part image-processing modules, we propose a browser-server style method. In the proposed solution, the PACS workstation shows the front-end user interface defined in an XML file while the image processing software is running in the background as a server. Inter-process communication (IPC) techniques allow an efficient exchange of image data, parameters, and user input between the PACS workstation and stand-alone image-processing software. Using a predefined communication protocol, the PACS workstation developer or image processing software developer does not need detailed information about the other system, but will still be able to achieve seamless integration between the two systems and the IPC procedure is totally transparent to the final user. A browser-server style solution was built between OsiriX (PACS workstation software) and MeVisLab (Image-Processing Software). Ten example image-processing modules were easily added to OsiriX by converting existing MeVisLab image processing networks. Image data transfer using shared memory added communication based on IPC techniques is an appealing method that allows PACS workstation developers and image processing software developers to cooperate while focusing on different interests.

  14. Trends in PACS image storage and archive.

    Science.gov (United States)

    Liu, B J; Cao, F; Zhou, M Z; Mogel, G; Documet, L

    2003-01-01

    PACS is widely used in hospitals and is considered a mission critical system for around-the-clock daily clinical operation. Scheduled or unscheduled downtime of the main PACS archive storage or server could potentially cripple the entire PACS operation. This is especially the case in a filmless hospital environment. Therefore, in a downtime event, it is most desirable for users to have only a minimal performance impact without interruption of clinical data flow or loss of data and to have available historical PACS studies. This paper summarizes some of the developments in the design and implementation of a reliable PACS that insures maximum uptime for end users while preserving the integrity of the PACS data and making it available during downtime events. It also details strategy for developing proper clinical workflow contingency procedures when a scheduled downtime event to the main archive storage and server occurs. Specifically, the design and implementation of a fault-tolerant (FT) main archive server, the development of a FT back-up archive using an application service provider (ASP) model, and the clinical experiences while upgrading a main archive server and migrating the stored PACS data to new storage media will be discussed. Copyright 2002 Elsevier Science Ltd.

  15. Performance Evaluation of a Clinical PACS Module

    Science.gov (United States)

    Taira, Ricky K.; Cho, Paul S.; Huang, H. K.; Mankovich, Nicholas J.; Boechat, Maria I.

    1989-05-01

    Picture archiving and communication systems (PACS) are now clinically available in limited radiologic applications. The benefits, acceptability, and reliablity of these systems have thus far been mainly speculative and anecdotal. This paper discusses the evaluation of a PACS module implemented in the pediatric radiology section of a 700-bed teaching hospital. The PACS manages all pediatric inpatient images including conventional x-rays and contrast studies (obtained with a computed radiography system), magnetic resonance images, and relevant ultrasound images. A six-monitor workstation is available for image review.

  16. Improvement of detectability of paratracheal air cyst (PAC) on MDCT

    International Nuclear Information System (INIS)

    Okumura, Yusuke; Takahashi, Shirou; Suzuki, Masayuki; Takemura, Akihiro

    2009-01-01

    A paratracheal air cyst (PAC) is located at the right paratracheal region in the thoracic inlet. Most of the patients with PAC are asymptomatic, while some are suffered from hemoptysis, dyspnea, and dysphagia. Therefore, knowledge of this entity is important. Here, we assessed the frequency, size and the CT features of PAC in the chest CT examinations using multi detector row-CT (MDCT). In addition, we examined the most appropriate imaging processes such as multi planar reconstruction (MPR), minimum intensity projection (MinIP), volume rendering (VR), and virtual endoscopy (VE) in demonstrating the PAC: peculiar diverticular structure. In the present study, we obtained in 70 PAC cases among 1,139 patients, representing a frequency of 6.1%. The CT features of PAC were sufficiently observed by several techniques. Thus we postulate that the imaging processes play an important role in diagnosis of PAC. (author)

  17. Dental PACS development in Korea

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Eun Kyung [Department of Oral and Maxillofacial Radiology, School of Dentistry, Dankook University, Cheonan (Korea, Republic of)

    2008-12-15

    Picture archiving and communication system (PACS) is an image information technology system for the transmission and storage of medical images. In Korea the first full PACS was installed at Samsung Medical Center in 1994, but, the rate of distribution was very slow. The government's approval for the medical insurance reimbursement for full PACS examinations in November 1999 became the turning point. Thereafter the number of hospitals with full PACS has steeply increased. In September of this year, PACS was installed at 906 medical institutes, including most of university hospitals and general hospitals. The first full dental PACS was installed at Wonkwang University Dental Hospital in 2002. Now ten out of eleven university dental hospitals implemented full dental PACS. The current status and technological factors of dental PACS in Korean university dental hospitals and the future perspectives of dental PACS are described.

  18. Dental PACS development in Korea

    International Nuclear Information System (INIS)

    Kim, Eun Kyung

    2008-01-01

    Picture archiving and communication system (PACS) is an image information technology system for the transmission and storage of medical images. In Korea the first full PACS was installed at Samsung Medical Center in 1994, but, the rate of distribution was very slow. The government's approval for the medical insurance reimbursement for full PACS examinations in November 1999 became the turning point. Thereafter the number of hospitals with full PACS has steeply increased. In September of this year, PACS was installed at 906 medical institutes, including most of university hospitals and general hospitals. The first full dental PACS was installed at Wonkwang University Dental Hospital in 2002. Now ten out of eleven university dental hospitals implemented full dental PACS. The current status and technological factors of dental PACS in Korean university dental hospitals and the future perspectives of dental PACS are described.

  19. Trends in PACS architecture

    International Nuclear Information System (INIS)

    Bellon, Erwin; Feron, Michel; Deprez, Tom; Reynders, Reinoud; Van den Bosch, Bart

    2011-01-01

    Radiological Picture Archiving and Communication Systems (PACS) have only relatively recently become abundant. Many hospitals have made the transition to PACS about a decade ago. During that decade requirements and available technology have changed considerably. In this paper we look at factors that influence the design of tomorrow's systems, especially those in larger multidisciplinary hospitals. We discuss their impact on PACS architecture (a technological perspective) as well as their impact on radiology (a management perspective). We emphasize that many of these influencing factors originate outside radiology and that radiology has little impact on these factors. That makes it the more important for managers in radiology to be aware of architectural aspects and it may change cooperation of radiology with, among others, the hospital's central IT department.

  20. PACS: Concepts and Trends

    Science.gov (United States)

    Bandon, David; Ratib, Osman; Lovis, Christian; Geissbuhler, Antoine

    Picture Archiving and Communication Systems (PACS) are becoming part of the core components of today's infrastructure for digital radiology. In modern setting they also extend to the whole medical enterprise and integrate into the patient medical record. While local architectures may vary significantly, the major features such as image archiving and retrieval, workflow management, workstations and image acquisition and quality control systems constitute the key elements of such systems. PACS has also vocation to extend beyond the radiological images to become the common platform for hospital wide management of all images. The wireless access can contribute to expand the scope of image distribution.

  1. MedPAC Data Book

    Data.gov (United States)

    U.S. Department of Health & Human Services — MedPACs Data Book is the result of discussions with congressional staff members regarding ways that MedPAC can better support them. Some of the information it...

  2. A strategic PACS maturity approach

    NARCIS (Netherlands)

    van de Wetering, R.

    2011-01-01

    Finding the key determinants of Picture Archivingand Communication Systems (PACS)performance in hospitals has been a conundrumfor decades. This research provides a method toassess the strategic alignment of PACS in hospitalsin order to find these key determinants. PACS touches upon every single part

  3. PACS pitfalls and bottlenecks

    Science.gov (United States)

    Huang, H. K.; Lou, Shyhliang A.; Wong, Albert W. K.

    1997-05-01

    PACS pitfalls are mostly created from human error, whereas bottlenecks are due to imperfect design in either the PACS or image acquisition devices. These drawbacks can only be realized through accumulated clinical experience. Pitfalls due to human error are often initiated at imaging acquisition devices and at workstations. Three major errors at the acquisition devices are entering wrong input parameters, stopping an image transmission process improperly, and incorrect patient positioning. The error occurring most often at the workstation happens when the user enters too many key strokes or clicks the mouse too often before the workstation can respond. Other pitfalls at the workstation unrelated to human error are missing location markers in a CT or MR scout view, images displayed with unsuitable look-up-tables, and white boarders in CR images due to x-ray collimation. Pitfalls created due to human intervention can be minimized by a better quality assurance program and periodic in-service training, and by interfacing image acquisition devices to the HIS/RIS. Bottlenecks affecting the PACS operation include network contention; CR, CT, and MR images stacked up at acquisition devices; slow response from workstations; and long delays for image retrieval from the long term archive. Bottlenecks can be alleviated by improving the system architecture, re- configuring the networks, and streamlining operational procedures through a gradual understanding of the clinical environment. We have identified most of the pitfalls and bottlenecks discussed above in our hospital-integrated PACS based on the past two years of clinical experience. This paper categorizes some of these problems, illustrates their effect on PACS operations, and suggests methods for circumventing them.

  4. Site Occupation of In in RAg{sub 6}In{sub 6} Studied Using PAC Spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Kruzel, M.; Krolas, K., E-mail: krolas@if.uj.edu.pl; Muszynski, L. [Jagiellonian University, Institute of Physics (Poland); Zaremba, V. I. [I. Franko National University of Lviv (Ukraine); Suski, W. [Polish Academy of Sciences (Poland)

    2004-11-15

    PAC measurements were performed for {sup 111}In in LaAg{sub 6}In{sub 6}, PrAg{sub 6}In{sub 6} and NdAg{sub 6}In{sub 6}. It appears that the probe atom occupy three available sites in the crystal lattice with quite a similar probability. There is a small preference for In atoms to occupy a selected lattice site which is not the same in different compounds.

  5. PACS Data Base Design

    Science.gov (United States)

    Zeleznik, Michael P.; Maguire, G. Q.; Baxter, B.

    1983-05-01

    A PACS database must manage three different types of data; structured data in the form of patient/exam identification information, and unstructured data in the form of text and images. Queries based on the content of text documents as well as the content of images must be suported, in addition to those based on standard, well structured keys such as name, age and sex. We model the PACS database as three logically distinct databases, each supporting one of these data types, with mapping structures relating all three. Several design issues which have a bearing, both on these models and on physical implemtations, are discussed. Because image database systems are the least understood at this time, most of the paper focusses on the them. We briefly discuss current trends in structured and text databases, without discussing commercial systems, and then present some current methods of implementing image database systems.

  6. Introduction to PAC/PAD

    International Nuclear Information System (INIS)

    Mahnke, H.E.

    1988-01-01

    Both methods, Perturbed Angular Correlation (PAC) utilizing radioactive probes and Perturbed Angular Distribution (PAD) following nuclear reactions measure hyperfine interaction parameters and allow to study magnetism on a rather local scale. While both techniques are based on the same theory the underlying concepts are quite different. Examples on local moments, influence of the nearest-neighbor to the magnetic field in ferromagnets, knight shift in nonmagnetic materials, and magnetism in high-temperature superconductors and related oxides illustrate the recent developments within the methods and the improvements in their sensitivity and resolution. (orig.)

  7. The Detector Physics and Applications Center - DePAC

    CERN Document Server

    Plothow-Besch, H; Fiorini, C; Grupen, C; Hassard, J; Longoni, A; Walenta, Albert H

    2001-01-01

    A new project, the 'Detector Physics and Applications Center (DePAC)', is presented. DePAC is a general detector and sensor database, which is not application specific, on the Internet. DePAC collects and explains the physics, the technology and the application of a wide range of radiation detectors. DePAC also collects and describes information about noise problems, front-end electronics, data transfer, processing and storage. DePAC provides short write-ups and source code of all sorts of detector related software depending on availability. DePAC collects useful constants and properties of materials in an exhaustive series of tables and graphs. DePAC also acts as a point of contact for researchers and industry in an interdisciplinary way, e.g. in biology, in medicine, in materials research and in high energy or nuclear physics. Last but not least, DePAC aims to develop also into a virtual lecturing school and serves as a tutorial for students and all interested scientists.

  8. The Detector Physics and Applications Center—DePAC

    Science.gov (United States)

    Plothow-Besch, H.; Besch, H.-J.; Fiorini, C.; Grupen, C.; Hassard, J.; Longoni, A.; Walenta, A. H.

    2001-09-01

    A new project, the "Detector Physics and Applications Center (DePAC)", is presented. DePAC is a general detector and sensor database, which is not application specific, on the Internet. DePAC collects and explains the physics, the technology and the application of a wide range of radiation detectors. DePAC also collects and describes information about noise problems, front-end electronics, data transfer, processing and storage. DePAC provides short write-ups and source code of all sorts of detector related software depending on availability. DePAC collects useful constants and properties of materials in an exhaustive series of tables and graphs. DePAC also acts as a point of contact for researchers and industry in an interdisciplinary way, e.g. in biology, in medicine, in materials research and in high energy or nuclear physics. Last but not least, DePAC aims to develop also into a virtual lecturing school and serves as a tutorial for students and all interested scientists.

  9. The Detector Physics and Applications Center - DePAC

    International Nuclear Information System (INIS)

    Plothow-Besch, H.; Besch, H.-J.; Fiorini, C.; Grupen, C.; Hassard, J.; Longoni, A.; Walenta, A.H.

    2001-01-01

    A new project, the 'Detector Physics and Applications Center (DePAC)', is presented. DePAC is a general detector and sensor database, which is not application specific, on the Internet. DePAC collects and explains the physics, the technology and the application of a wide range of radiation detectors. DePAC also collects and describes information about noise problems, front-end electronics, data transfer, processing and storage. DePAC provides short write-ups and source code of all sorts of detector related software depending on availability. DePAC collects useful constants and properties of materials in an exhaustive series of tables and graphs. DePAC also acts as a point of contact for researchers and industry in an interdisciplinary way, e.g. in biology, in medicine, in materials research and in high energy or nuclear physics. Last but not least, DePAC aims to develop also into a virtual lecturing school and serves as a tutorial for students and all interested scientists

  10. Studi Perbandingan Keefektifan Penggunaan Poly Aluminium Chloride (PAC) dan Tawas (Alum) Terhadap Turbiditas dan Kadar Logam Aluminium Pada Air Baku Instalasi Pengolahan Air Di PDAM Tirtanadi Hamparan Perak

    OpenAIRE

    Gea, Deswanti Mariana

    2017-01-01

    The comparative effectiveness study of the usage of the poly aluminium chloride (PAC) and alum towards the turbidity and the aluminium levels at the water treatment installation of PDAM Hamparan Perak has been carried out. The concentration of aluminium chloride and alum usage compared in the raw water has initial turbidity 73,3 NTU and aluminium levels of 0,048 mg/l is respectively 19 ppm; 21 ppm and 23 ppm. And being stirred with agiator found in the Jar Test with a 140 rpm rotation spee...

  11. Technical feasibility study of a low-cost hybrid PAC-UF system for wastewater reclamation and reuse: a focus on feedwater production for low-pressure boilers.

    Science.gov (United States)

    Amosa, Mutiu Kolade; Jami, Mohammed Saedi; Alkhatib, Ma'an Fahmi R; Majozi, Thokozani

    2016-11-01

    This study has applied the concept of the hybrid PAC-UF process in the treatment of the final effluent of the palm oil industry for reuse as feedwater for low-pressure boilers. In a bench-scale set-up, a low-cost empty fruit bunch-based powdered activated carbon (PAC) was employed for upstream adsorption of biotreated palm oil mill effluent (BPOME) with the process conditions: 60 g/L dose of PAC, 68 min of mixing time and 200 rpm of mixing speed, to reduce the feedwater strength, alleviate probable fouling of the membranes and thus improve the process flux (productivity). Three polyethersulfone ultrafiltration membranes of molecular weight cut-off (MWCO) of 1, 5 and 10 kDa were investigated in a cross-flow filtration mode, and under constant transmembrane pressures of 40, 80, and 120 kPa. The permeate qualities of the hybrid processes were evaluated, and it was found that the integrated process with the 1 kDa MWCO UF membrane yielded the best water quality that falls within the US EPA reuse standard for boiler-feed and cooling water. It was also observed that the permeate quality is fit for extended reuse as process water in the cement, petroleum and coal industries. In addition, the hybrid system's operation consumed 37.13 Wh m -3 of energy at the highest applied pressure of 120 kPa, which is far lesser than the typical energy requirement range (0.8-1.0 kWh m -3 ) for such wastewater reclamation.

  12. bond activation and catalysis by Ru -pac complexes (pac ...

    Indian Academy of Sciences (India)

    such Ru(III)-pac systems in such detail. The mechanis- tic information described above suggests that Ru-pac complexes could be promising species with regard to potential biological applications, especially in the elu- cidation of the mechanisms of reactive intermediates formed in enzymatic oxygenation reactions that could.

  13. Predicting clinical image delivery time by monitoring PACS queue behavior.

    Science.gov (United States)

    King, Nelson E; Documet, Jorge; Liu, Brent

    2006-01-01

    The expectation of rapid image retrieval from PACS users contributes to increased information technology (IT) infrastructure investments to increase performance as well as continuing demands upon PACS administrators to respond to "slow" system performance. The ability to provide predicted delivery times to a PACS user may curb user expectations for "fastest" response especially during peak hours. This, in turn, could result in a PACS infrastructure tailored to more realistic performance demands. A PACS with a stand-alone architecture under peak load typically holds study requests in a queue until the DICOM C-Move command can take place. We investigate the contents of a stand-alone architecture PACS RetrieveSend queue and identified parameters and behaviors that enable a more accurate prediction of delivery time. A prediction algorithm for studies delayed in a stand-alone PACS queue can be extendible to other potential bottlenecks such as long-term storage archives. Implications of a queue monitor in other PACS architectures are also discussed.

  14. Pituitary adenylate cyclase-activating peptide (PACAP) and PAC1 receptor in the testis of cartilaginous fish Torpedo marmorata: A molecular and phylogenetic study.

    Science.gov (United States)

    Agnese, Marisa; Valiante, Salvatore; Rosati, Luigi; Andreuccetti, Piero; Prisco, Marina

    2016-01-01

    The role of PACAP in spermatogenesis and steroidogenesis has been largely investigated in last years in mammals; conversely, a few studies have been performed in non mammalian vertebrates. In this paper we investigated the sequence, expression and localization of PACAP and its PAC1 receptor in the testis of the benthic elasmobranch Torpedo marmorata, the marbled electric ray. Cloning a partial PACAP cDNA, we demonstrated for the first time in elasmobranches that PACAP shows a highly conserved sequence, compared with the PACAP of other chordates (tunicates and vertebrates). Moreover, the phylogenetic analysis revealed that PACAP has been well preserved during evolution and that a negative selection acts on PACAP sequence, leading to the conservation of the coding sites. The phylogenetic consensus tree showed also that Torpedo PACAP is more related with the amphibian PACAP than with the teleost one. Finally, we demonstrated that in T. marmorata PACAP and its PAC1 receptor are synthesized directly in the testis, where they show a wider localization than mammals, suggesting that this neuropeptide is involved in the control of Torpedo spermatogenesis. Copyright © 2015 Elsevier Inc. All rights reserved.

  15. Temperature dependence of the EFG at Cd-doped Lu2O3: How ab initio calculations can complement PAC experiments

    International Nuclear Information System (INIS)

    Errico, L.A.; Renteria, M.; Bibiloni, A.G.; Darriba, G.N.

    2005-01-01

    We report an ab initio study of the temperature dependence of the electric-field gradient (EFG) tensor at Cd impurities replacing cations in Lu 2 O 3 . Calculations were performed with the Full-Potential Linearized-Augmented Plane Wave method that allows us to treat the electronic structure and the processes induced by the impurity in the host-lattice without the use of external parameters. In this new insight, the EFG thermal dependence arises from the ionization of an impurity acceptor level introduced in the band-gap of Lu 2 O 3 by Cd impurities, in good agreement with a previously proposed two state model. (copyright 2005 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  16. Temperature dependence of the EFG at Cd-doped Lu{sub 2}O{sub 3}: How ab initio calculations can complement PAC experiments

    Energy Technology Data Exchange (ETDEWEB)

    Errico, L.A.; Renteria, M.; Bibiloni, A.G.; Darriba, G.N. [Departamento de Fisica, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, CC 67, 1900 La Plata (Argentina)

    2005-08-01

    We report an ab initio study of the temperature dependence of the electric-field gradient (EFG) tensor at Cd impurities replacing cations in Lu{sub 2}O{sub 3}. Calculations were performed with the Full-Potential Linearized-Augmented Plane Wave method that allows us to treat the electronic structure and the processes induced by the impurity in the host-lattice without the use of external parameters. In this new insight, the EFG thermal dependence arises from the ionization of an impurity acceptor level introduced in the band-gap of Lu{sub 2}O{sub 3} by Cd impurities, in good agreement with a previously proposed two state model. (copyright 2005 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  17. PACS infrastructure supporting e-learning

    International Nuclear Information System (INIS)

    Mildenberger, Peter; Brueggemann, Kerstin; Roesner, Freya; Koch, Katja; Ahlers, Christopher

    2011-01-01

    Digital imaging is becoming predominant in radiology. This has implications for teaching support, because conventional film-based concepts are now obsolete. The IHE Teaching File and Clinical Study Export (TCE) profile provides an excellent platform to enhance PACS infrastructure with educational functionality. This can be supplemented with dedicated e-learning tools.

  18. A Situational Alignment Framework for PACS

    NARCIS (Netherlands)

    van de Wetering, Rogier; Batenburg, Ronald; Oudkerk, Matthijs; van Ooijen, Peter; Brinkkemper, Sjaak; Scheper, Wim

    2011-01-01

    This paper reports the outcomes of a study on an integrated situational alignment framework for picture archiving and communication systems (PACS) labeled as PISA. Following the design research cycle, complementary validation methods and pilot cases were used to assess the proposed framework and its

  19. PAC-Learning from General Examples

    DEFF Research Database (Denmark)

    Fischer, Paul; Hoeffgen, K.- U.; Lefmann, H.

    1997-01-01

    We study a novel view on the PAC learning model in which the examples are more complicated than in the standard model. There, an example usually is an element of the learning domain and its label indicates whether it belongs to the target concept. Here, the examples can be subsets and their label...

  20. PACS infrastructure supporting e-learning

    Energy Technology Data Exchange (ETDEWEB)

    Mildenberger, Peter, E-mail: milden@radiologie.klinik.uni-mainz.de [University Medicine Mainz, Johannes Gutenberg-University Mainz, Langenbeckstr 1, Mainz (Germany); Brueggemann, Kerstin; Roesner, Freya; Koch, Katja; Ahlers, Christopher [University Medicine Mainz, Johannes Gutenberg-University Mainz, Langenbeckstr 1, Mainz (Germany)

    2011-05-15

    Digital imaging is becoming predominant in radiology. This has implications for teaching support, because conventional film-based concepts are now obsolete. The IHE Teaching File and Clinical Study Export (TCE) profile provides an excellent platform to enhance PACS infrastructure with educational functionality. This can be supplemented with dedicated e-learning tools.

  1. Effect of PAC dosage in a pilot-scale PAC-MBR treating micro-polluted surface water.

    Science.gov (United States)

    Hu, Jingyi; Shang, Ran; Deng, Huiping; Heijman, Sebastiaan G J; Rietveld, Luuk C

    2014-02-01

    To address the water scarcity issue and advance the traditional drinking water treatment technique, a powdered activated carbon-amended membrane bioreactor (PAC-MBR) is proposed for micro-polluted surface water treatment. A pilot-scale study was carried out by initially dosing different amounts of PAC into the MBR. Comparative results showed that 2g/L performed the best among 0, 1, 2 and 3g/L PAC-MBR regarding organic matter and ammonia removal as well as membrane flux sustainability. 1g/L PAC-MBR exhibited a marginal improvement in pollutant removal compared to the non-PAC system. The accumulation of organic matter in the bulk mixture of 3g/L PAC-MBR led to poorer organic removal and severer membrane fouling. Molecular weight distribution of the bulk liquid in 2g/L PAC-MBR revealed the synergistic effects of PAC adsorption/biodegradation and membrane rejection on organic matter removal. Additionally, a lower amount of soluble extracellular polymer substances in the bulk can be secured in 21 days operation. Copyright © 2013 Elsevier Ltd. All rights reserved.

  2. Small PACS implementation using publicly available software

    Science.gov (United States)

    Passadore, Diego J.; Isoardi, Roberto A.; Gonzalez Nicolini, Federico J.; Ariza, P. P.; Novas, C. V.; Omati, S. A.

    1998-07-01

    Building cost effective PACS solutions is a main concern in developing countries. Hardware and software components are generally much more expensive than in developed countries and also more tightened financial constraints are the main reasons contributing to a slow rate of implementation of PACS. The extensive use of Internet for sharing resources and information has brought a broad number of freely available software packages to an ever-increasing number of users. In the field of medical imaging is possible to find image format conversion packages, DICOM compliant servers for all kinds of service classes, databases, web servers, image visualization, manipulation and analysis tools, etc. This paper describes a PACS implementation for review and storage built on freely available software. It currently integrates four diagnostic modalities (PET, CT, MR and NM), a Radiotherapy Treatment Planning workstation and several computers in a local area network, for image storage, database management and image review, processing and analysis. It also includes a web-based application that allows remote users to query the archive for studies from any workstation and to view the corresponding images and reports. We conclude that the advantage of using this approach is twofold. It allows a full understanding of all the issues involved in the implementation of a PACS and also contributes to keep costs down while enabling the development of a functional system for storage, distribution and review that can prove to be helpful for radiologists and referring physicians.

  3. History of PACS in Asia

    International Nuclear Information System (INIS)

    Inamura, Kiyonari; Kim, Jong Hyo

    2011-01-01

    First, history of PACS (picture archiving and communication system for medical use) in Japan is described in two parts: in part 1, the early stage of PACS development from 1984 to 2002, and in part 2 the matured stage from 2002 to 2010. PACS in Japan has been developed and installed by local manufacturers by their own technology and demand from domestic hospitals. Part 1 mainly focuses on quantitative growth and part 2 on qualitative change. In part 2, integration of PACS into RIS (radiology information system), HIS (hospital information system), EPR (electronic patient record), teleradiology and IHE (integrating healthcare enterprise) is reported. Interaction with other elements of technology such as moving picture network system and three dimensional display is also discussed. Present situation of main 4 large size hospitals is presented. Second, history of PACS in Korea is reported. Very acute climbing up of filmless PACS diffusion was observed from 1997 to 2000. The reasons for such evolution are described and discussed. Also changes of PACS installation and system integration with other systems such as HIS and role of them in radiological diagnoses in Korea since 2002 are described. Third, history in China is investigated by checking international academic journals in English and described as far as events are logically linked and consistently meaningful.

  4. Pb(II) and Hg(II) binding to $\\textit{de novo}$ designed proteins studied by $^{204m}$Pb- and $^{199m}$Hg-Perturbed Angular Correlation of $\\gamma$-rays (PAC) spectroscopy : Clues to heavy metal toxicity

    CERN Multimedia

    2002-01-01

    $\\textit{De novo}$ design of proteins combined with PAC spectroscopy offers a unique and powerful approach to the study of fundamental chemistry of heavy metal-protein interactions, and thus of the mechanisms underlying heavy metal toxicity. In this project we focus on Pb(II) and Hg(II) binding to designed three stranded coiled coil proteins with one or two binding sites, mimicking a variety of naturally occurring thiolate-rich metal ion binding sites in proteins. The $^{204m}$Pb- and $^{199m}$Hg-PAC experiments will complement data already recorded with EXAFS, NMR, UV-Vis and CD spectroscopies.

  5. Incremental cost of PACS in a medical intensive care unit

    Science.gov (United States)

    Langlotz, Curtis P.; Cleff, Bridget; Even-Shoshan, Orit; Bozzo, Mary T.; Redfern, Regina O.; Brikman, Inna; Seshadri, Sridhar B.; Horii, Steven C.; Kundel, Harold L.

    1995-05-01

    Our purpose is to determine the incremental costs (or savings) due to the introduction of picture archiving and communication systems (PACS) and computed radiology (CR) in a medical intensive care unit (MICU). Our economic analysis consists of three measurement methods. The first method is an assessment of the direct costs to the radiology department, implemented in a spreadsheet model. The second method consists of a series of brief observational studies to measure potential changes in personnel costs that might not be reflected in administrative claims. The third method (results not reported here) is a multivariate modeling technique which estimates the independent effect of PACS/CR on the cost of care (estimated from administrative claims data), while controlling for clinical case- mix variables. Our direct cost model shows no cost savings to the radiology department after the introduction of PACS in the medical intensive care unit. Savings in film supplies and film library personnel are offset by increases in capital equipment costs and PACS operation personnel. The results of observational studies to date demonstrate significant savings in clinician film-search time, but no significant change in technologist time or lost films. Our model suggests that direct radiology costs will increase after the limited introduction of PACS/CR in the MICU. Our observational studies show a small but significant effect on clinician film search time by the introduction of PACS/CR in the MICU, but no significant effect on other variables. The projected costs of a hospital-wide PACS are currently under study.

  6. The management and realizing of image data flow in PACS

    International Nuclear Information System (INIS)

    Tao Yonghao; Miao Jingtao

    2002-01-01

    Objective: To explore the management model and realizing of PACS image data-flow. Methods: Based on the implementing environment and management model of PACS image data-flow after full digital reengineering for radiology department in Shanghai First Hospital was completed, analysis on image data flow types, procedure, and achieving pattern were conducted. Results: Two kinds of image data-flow management were set up for the PACS of Shanghai First Hospital, which included image archiving procedure and image forward procedure. The former was implemented with central management model while the latter was achieved with a program that functionally acted as workflow management running on the central server. Conclusion: The image data-flow management pattern, as a key factor for PACS, has to be designed and implemented functionally and effectively depending on the performance environment, the tasks and requirements specified to particular user

  7. Medical imaging, PACS, and imaging informatics: retrospective.

    Science.gov (United States)

    Huang, H K

    2014-01-01

    . (Konica-Minolta), Japan, in the 1980-1990s. Major support from the US National Institutes of Health and other federal agencies and private medical imaging industry are appreciated. The NATO (North Atlantic Treaty Organization) Advanced Study Institute (ASI) sponsored the International PACS Conference at Evian, France, in 1990, the contents and presentations of which convinced a half dozen high-level US military healthcare personnel, including surgeons and radiologists, that PACS was feasible and would greatly streamline the current military healthcare services. The impact of the post-conference summary by these individuals to their superiors opened the doors for long-term support of PACS development by the US Military Healthcare Services. PACS and imaging informatics have thus emerged as a daily clinical necessity.

  8. Acceptance of PACS utilizing a PACS QI Program.

    Science.gov (United States)

    Stockman, Troy; Krishnan, Santha

    2006-01-01

    This article describes the quality improvement program that Mercy Hospital (Alegent Health System) initiated after it implemented a picture archiving and communication system (PACS) in November 2003. The radiology department encountered numerous PACS-related issues that directly affected the quality and workflow of patient care. In order to get a better understanding of the situation, the department developed a quality improvement plan for its PACS program. The first step was to dedicate a resource--in this case, a radiology information technology (RIT) support specialist--who would serve as a PACS subject matter expert while dealing with day-to-day PACS-related issues--specifically, errors. The error data were collected and categorized for consistency using statistical process control (SPC) tools. The information gathered was then traced back to the team members responsible for the errors and used as a training tool to further educate them. As a result of this program, the average error rate was reduced from 12% to 4% because the radiology team developed a better understanding of the errors by identifying the root causes and being accountable for eliminating errors within their control. In addition, the radiology staff learned to accept and trust the PACS, resulting in a positive culture change that benefited teamwork and staff morale as well as improve the workflow and the quality of patient care.

  9. Ionic exchange and the local structure in the HfO2/Ho2O3 system studied by PAC spectroscopy

    International Nuclear Information System (INIS)

    Richard, D.; Darriba, G.N.; Muñoz, E.L.; Errico, L.A.; Rentería, M.

    2014-01-01

    Highlights: • Suitability of PAC spectroscopy to study inter-diffusion processes. • High level of ionic exchange obtained by ball-milling and thermal treatments. • EFG characterization of 181 Ta impurities at defect-free cation sites of Ho 2 O 3 . • Excellent agreement with other EFG results in bixbyites and ab initio calculations. • A new Ho-doped m-HfO 2 phase was characterized. - Abstract: The ionic exchange of Hf and Ho atoms in the HfO 2 /Ho 2 O 3 system was studied at the atomic level applying the nuclear solid-state Time-Differential γ–γ Perturbed-Angular-Correlation (PAC) spectroscopy. This exchange was promoted by a ball-milling-assisted solid-state reaction between Ho 2 O 3 and m-HfO 2 initial powders. In order to follow and to elucidate the effect of different variables (milling time, temperature, pressure) on the exchange process and the appearance of new phases, 181 Hf(→ 181 Ta) ions were used as local probes in the PAC experiments. The measured hyperfine interactions enabled the electric-field gradient tensor (EFG) characterization at Hf sites at each step of the process. At the final stages of the solid-state reaction, 75–90% Hf-doping at both substitutional defect-free cation sites of Ho 2 O 3 was achieved, being the EFG measured at these sites in excellent agreement with those determined in 181 Hf-implanted Ho 2 O 3 samples and to those predicted by the EFG systematics established in rare-earth bixbyites doped by ion-implantation of 181 Hf(→ 181 Ta) ions. Ab initio electronic structure calculations of the EFG at Ta impurities localized at both cation sites in Ho 2 O 3 also confirm the 181 Hf cationic substitution in both PAC experiments. Additional ab initio calculations at Hf impurity sites in Ho 2 O 3 and Tm 2 O 3 were performed to study the relative Hf preference for the symmetric site of the structure. We showed that high-energy milling plus high temperature treatments are both necessary to achieve a high degree of Hf

  10. Partners Against Crime (PAC) Districts

    Data.gov (United States)

    City and County of Durham, North Carolina — The Partners Against Crime (PAC) program promotes collaboration among police officers, Durham residents, and city and county government officials to find...

  11. PACS policies and procedures.

    Science.gov (United States)

    Knepper, Daniel

    2007-01-01

    Documentation of policies and procedures are critical for the proper operation and management of a picture archival and communication system (PACS). Policies, procedures, and site specific documentation may be organized in several categories. Through the use of broad categories one can easily begin to break down the specific areas which require attention and prioritize them as necessary. One way to categorize them is: administration, maintenance, support, architecture and integration, and disaster recovery/business continuity. One area that requires a great deal of focus and discipline is a policy for "change management." It is essential to have a policy in place for making changes to the information system. This would include not only changes to the system such as software upgrades, but changes to workflows such as how images are being distributed, compression settings, network settings, monitor settings, locations of workstations, integration, and disaster recovery/ business continuity. Modifying existing information technology (IT) policies and using published resources can largely simplify the development of organization specific policies and procedures.

  12. Can paper replace laser film to communicate the results of wrist radiographs in trauma cases? A reproducibility study of the reading of wrist trauma case radiographs on a PACS workstation, laser film, and paper.

    Science.gov (United States)

    Teixeira, Pedro; Zabel, Jean-Philippe; Baumann, Cédric; Albizzati, Stéphane; Coudane, Henry; Winninger, Daniel; Blum, Alain

    2013-12-01

    The main goal of this study was to determine the reproducibility of the reading of wrist trauma case radiographs using three different media: laser film, a picture archiving and communication systems (PACS) workstation, and paper with an optimized layout. The study was conducted retrospectively in 200 consecutive patients consulting at the emergency department for wrist trauma and who underwent wrist X-ray investigation using a computed radiography system. There were 82 men and 118 women. The mean age was 48.3 years (16-95 years). Our institutional review board does not require patient approval or informed consent for retrospective review of case records. The readings were made by two independent readers who analyzed the 200 patient radiographs consecutively in one session for each type of media: paper, laser film, and on a PACS dual-screen workstation. The inter-reader agreements were substantial or almost perfect, with kappa values of 0.83 (0.76-0.90) for the PACS, 0.83 (0.76-0.90) for film, and 0.80 (0.72-0.87) for paper. The inter-technique agreement was almost perfect in all cases. There is a high interobserver agreement between PACS, laser film, and paper readings for wrist trauma cases. With a layout of one radiograph on each sheet, paper could replace laser films to communicate the results of wrist radiographs in trauma cases for outpatients.

  13. Patriot PAC-2 Development and Deployment in The Gulf War

    National Research Council Canada - National Science Library

    Sherman, J

    2003-01-01

    .... Patriot PAC-2 is a case study in effective project management that resulted in the extraordinary acceleration in the final stages of development production and deployment in time to play a historic role in the Gulf War...

  14. Evaluation of PACS in a multihospital environment

    Science.gov (United States)

    Siegel, Eliot L.; Reiner, Bruce I.; Protopapas, Zenon

    1998-07-01

    Although a number of authors have described the challenges and benefits of filmless operation using a hospital-wide Picture Archival and Communication System (PACS), there have been few descriptions of a multi-hospital wide area PACS. The purpose of this paper is to describe our two and a half year experience with PACS in an integrated multi-facility health care environment, the Veterans Affairs Maryland Health Care System (VAMHCS). On June 17, 1995 the Radiology and Nuclear Medicine services became integrated for four medical centers forming the VA Maryland Health Care System creating a single multi-facility imaging department. The facilities consisted of the Baltimore VA (acute and outpatient care, tertiary referral center), Ft. Howard (primarily long term care), Perry Point (primarily psychiatric care), and the Baltimore Rehabilitation and extended care facility (nursing home). The combined number of studies at all four sites is slightly more than 80,000 examinations per year. In addition to residents and fellows, the number of radiologists at Baltimore was approximately seven, with two at Perry Point, one at Ft. Howard, and no radiologists at the Rehabilitation and Extended Care facility. A single HIS/RIS, which is located physically at the Baltimore VAMC is utilized for all four medical centers. The multi- facility image management and communication system utilizes two separate PAC Systems that are physically located at the Baltimore VA Medical Center (BVAMC). The commercial system (GE Medical Systems) has been in place in Baltimore for more than 41/2 years and is utilized primarily in the acquisition, storage, distribution and display of radiology and nuclear medicine studies. The second PACS is the VISTA Imaging System, which has been developed as a module of the VA's HIS/RIS by and for the Department of Veterans Affairs. All of the radiology images obtained on the commercial PACS are requested by the VISTA Imaging System using DICOM query/retrieve commands

  15. PCaPAC 2006 Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Pavel Chevtsov; Matthew Bickley (Eds.)

    2007-03-30

    The 6-th international PCaPAC (Personal Computers and Particle Accelerator Controls) workshop was held at Jefferson Lab, Newport News, Virginia, from October 24-27, 2006. The main objectives of the conference were to discuss the most important issues of the use of PCs and modern IT technologies for controls of accelerators and to give scientists, engineers, and technicians a forum to exchange the ideas on control problems and their solutions. The workshop consisted of plenary sessions and poster sessions. No parallel sessions were held.Totally, more than seventy oral and poster presentations as well as tutorials were made during the conference, on the basis of which about fifty papers were submitted by the authors and included in this publication. This printed version of the PCaPAC 2006 Proceedings is published at Jefferson Lab according to the decision of the PCaPAC International Program Committee of October 26, 2006.

  16. Identification of PAC1 receptor isoform mRNAs by real-time PCR in rat suprachiasmatic nucleus.

    Science.gov (United States)

    Ajpru, Supaporn; McArthur, Angela J; Piggins, Hugh D; Sugden, David

    2002-09-30

    The pituitary adenylate cyclase-activating polypeptide (PACAP) has been implicated in the photic resetting of the rodent circadian clock in the suprachiasmatic nucleus (SCN). PACAP can exert its effects via VPAC1, VPAC2 and PAC1 G-protein coupled receptors. PAC1 and VPAC2, but not VPAC1, mRNA is expressed in rat SCN. A variety of PAC1 receptor splice variants have been described showing differences in ligand binding affinity and selectivity, G-protein coupling and ability to activate signal transduction pathways. The present experiments used PCR with isoform specific primers to determine which PAC1 variants are expressed in rat SCN. The PAC1(null) isoform and a variant containing a single 28-amino acid insert in the third intracellular (IC3) loop (hop1/2) were detected. No other IC3 variants (hip, hip-hop), N-terminal variants (PAC1(short), PAC1(very short) and PAC1(3a)) or the variant differing in transmembrane II and IV (PAC1TM4) were detected in SCN obtained at any time of day. A quantitative real-time PCR assay was established which measured combined expression of the PAC1(null/hop) variants in rat SCN during a 12:12-h light:dark (L:D) cycle. There was no significant variation of PAC1 mRNA expression (PAC1(null)+PAC1(hop)) with time of day. Nor was there a significant difference in the proportion of these two variants with time of day. These results indicate that the phase-dependency of the actions of PACAP on SCN firing and circadian behaviour are not mediated by changes in the level of expression of PAC1 receptor mRNA, nor by phase-dependent expression of PAC1 receptor variants with altered ligand binding, G-protein coupling or signalling characteristics. Copyright 2002 Elsevier Science B.V.

  17. Integrated RIS-PACS system

    International Nuclear Information System (INIS)

    Nishihara, Eitaro; Kura, Hiroyuki; Fukushima, Yuki

    1994-01-01

    We have developed an integrated RIS-PACS (radiology information system-picture archiving and communication system) system which supports examination, interpretation, and management in the diagnostic imaging department. The system was introduced in the Toshiba Hospital in May 1993, concurrently with the renewal of the hospital facilities. The integrated RIS-PACS system consists of a radiology information management system, and an image management system. The system supports wet (immediate) reading and chronological comparative reading using viewing workstation, enables routine operations to be performed in the diagnostic imaging department without film transportation, and contributes to the improvement of management efficiency in the department. (author)

  18. bond activation and catalysis by Ru -pac complexes (pac ...

    Indian Academy of Sciences (India)

    Ru-pac complexes exhibit catalytic properties,1 in homogeneous conditions in the presence of oxygen atom donors, that mimic the biological enzymatic oxi- dation of hydrocarbons by cytochrome P-450.2,3 The natural P-450 enzymes when treated with an oxy- gen atom transfer agent such as H2O2 in the pre- sence of ...

  19. Effect of powdered activated carbon (PAC) on MBR performance and effluent trihalomethane formation: At the initial stage of PAC addition.

    Science.gov (United States)

    Gao, Yue; Ma, Defang; Yue, Qinyan; Gao, Baoyu; Huang, Xia

    2016-09-01

    In this study, the MBR was used to treat municipal wastewater for reuse. Effects of powdered activated carbon (PAC) addition on MBR system in terms of effluent water quality, trihalomethane (THM) formation and membrane organic fouling tendency of MBR sludge supernatant at the initial stage of PAC addition were investigated. Effects of chlorine dose and contact time on THM formation and speciation were also studied. PAC addition enhanced the removal of organic matters, especially aromatic components, which improved the UV254 removal rate from 34% to 83%. PAC addition greatly reduced the membrane organic fouling tendency of MBR sludge supernatant. PAC addition reduced the MBR effluent trihalomethane formation potential (THMFP) from 351.29 to 241.95μg/L, while increased THM formation reactivity by 42%. PAC addition enhanced the formation of higher toxic bromine-containing THMs. High chlorine dose and contact time resulted in higher THM formation but lower proportion of bromine-containing THMs. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. Urological diagnosis using clinical PACS

    Science.gov (United States)

    Mills, Stephen F.; Spetz, Kevin S.; Dwyer, Samuel J., III

    1995-05-01

    Urological diagnosis using fluoroscopy images has traditionally been performed using radiographic films. Images are generally acquired in conjunction with the application of a contrast agent, processed to create analog films, and inspected to ensure satisfactory image quality prior to being provided to a radiologist for reading. In the case of errors the entire process must be repeated. In addition, the radiologist must then often go to a particular reading room, possibly in a remote part of the healthcare facility, to read the images. The integration of digital fluoroscopy modalities with clinical PACS has the potential to significantly improve the urological diagnosis process by providing high-speed access to images at a variety of locations within a healthcare facility without costly film processing. The PACS additionally provides a cost-effective and reliable means of long-term storage and allows several medical users to simultaneously view the same images at different locations. The installation of a digital data interface between the existing clinically operational PACS at the University of Virginia Health Sciences Center and a digital urology fluoroscope is described. Preliminary user interviews that have been conducted to determine the clinical effectiveness of PACS workstations for urological diagnosis are discussed. The specific suitability of the workstation medium is discussed, as are overall advantages and disadvantages of the hardcopy and softcopy media in terms of efficiency, timeliness and cost. Throughput metrics and some specific parameters of gray-scale viewing stations and the expected system impacts resulting from the integration of a urology fluoroscope with PACS are also discussed.

  1. PACS strategy for imaging centers.

    Science.gov (United States)

    Bedel, Victoria; Zdanowicz, Mark

    2004-01-01

    Picture archiving and communications systems (PACS) have been available in imaging centers for many years, but they often were less functional, were not well integrated into patient information systems, and lacked the network backbone to implement a system. As modalities are replaced and technology improves, the ability and time for an imaging center to acquire, integrate, and utilize PACS has arrived. However, each imaging center must determine why it should invest in PACS. A business plan is the fundamental need. Each imaging center must understand its target market, growth rate, and staffing plans. Additional considerations lie in current and future modality availability, the need for offsite delivery of images and reports, and the potential need for remote transmission of images. These issues must be identified and prioritized. A multidisciplinary team is essential. The most successful PACS implementation begins with complete involvement from all levels. The team should be comprised of people with complementary skills who are committed to a common purpose, set of performance goals, and approach for which they hold themselves mutually accountable. The team must jointly decide on the project's objectives. These objectives fall under 4 categories: clinical, service, financial, and performance. PACS must be considered a tool to help accomplish each objective. The imaging center must determine its top priorities, then translate them into a technology "wish list." The center can then list those pieces of technology that are most important and prioritize them. There are even more considerations for connecting multiple imaging centers. The team must create a comprehensive request for proposal (RFP) and determine the vendors that will receive the document. Once the RFP responses have been received and the vendor has been selected, an effective training plan must be executed. Training plans should be competency-based, ensuring comfort and competency among all staff. Upon

  2. Src family kinase inhibitors blunt PACAP-induced PAC1 receptor endocytosis, phosphorylation of ERK, and the increase in cardiac neuron excitability.

    Science.gov (United States)

    Tompkins, John D; Clason, Todd A; Buttolph, Thomas R; Girard, Beatrice M; Linden, Anne K; Hardwick, Jean C; Merriam, Laura A; May, Victor; Parsons, Rodney L

    2018-02-01

    Pituitary adenylate cyclase activating polypeptide (PACAP, Adcyap1) activation of PAC1 receptors ( Adcyap1r1) significantly increases excitability of guinea pig cardiac neurons. This modulation of excitability is mediated in part by plasma membrane G protein-dependent activation of adenylyl cyclase and downstream signaling cascades. However, additional mechanisms responsible for the enhanced excitability are activated following internalization of the PAC1 receptor and endosomal signaling. Src family kinases play critical roles mediating endocytosis of many trophic factor and G protein-coupled receptors. The present study investigated whether Src family kinases also support the PACAP-induced PAC1 receptor internalization, phosphorylation of ERK, and enhanced neuronal excitability. Using human embryonic kidney cells stably expressing a green fluorescent protein-tagged PAC1 receptor, treatment with the Src family kinase inhibitor PP2 (10 µM) markedly reduced the PACAP-induced PAC1 receptor internalization, and in parallel, both PP2 and Src inhibitor 1 (Src-1, 2 µM) reduced ERK activation determined by Western blot analysis. In contrast, Src family kinase inhibitors did not eliminate a PACAP-induced rise in global calcium generated by inositol (1,4,5)-trisphosphate-induced release of calcium from endoplasmic reticulum stores. From confocal analysis of phosphorylated ERK immunostaining, PP2 treatment significantly attenuated PACAP activation of ERK in neurons within cardiac ganglia whole mount preparations. Intracellular recordings demonstrated that PP2 also significantly blunted a PACAP-induced increase in cardiac neuron excitability. These studies demonstrate Src-related kinase activity in PAC1 receptor internalization, activation of MEK/ERK signaling, and regulation of neuronal excitability. The present results provide further support for the importance of PAC1 receptor endosomal signaling as a key mechanism regulating cellular function.

  3. Web based emergency room PACS

    International Nuclear Information System (INIS)

    Cha, Soon Joo; Cheon, Yong Kyung; Choi, Sung Woo Kim

    2005-01-01

    We wished to develop the web based Picture Archiving and Communication System in the emergency room for early decision making in emergency treatment planning at a full PACS Hospital. The program tools were Microsoft Visual Studio 6.0 - Visual C++ 6.0, and the Microsoft SQL 7.0 under the Microsoft Windows 2000 server operation system. The achievement of images was performed by an auto transport program installed in the ER and the radiology department. The average compression rates were 5:1 for CT and MR, and 20:1 for CR with JPEG 2000 lossy compression. All the images were stored on hard disk for 3 months. The patients' information was displayed for 2 weeks for reducing the security risk. For interdepartmental consultation, patient query by patient hospital number was available. Our Web based ER PACS could be useful system for early decision making for treatment planning in the emergency room because it reduces the risk factors for the security of the Web Paces by using a system independent from PACS in the hospital and minimizing the information patients

  4. Issues and solutions for interfacing a PACS database with an RIS

    Science.gov (United States)

    Breant, Claudine M.; Taira, Ricky K.; Tashima, Gregory H.; Huang, H. K.

    1992-07-01

    We describe the interfacing methods between our departments RIS (Radiological Information System) and PACS database. Sharing information has become an increasingly important issue for both systems. RIS study information should be available at the PACS workstation to complete the image description. Patient scheduling, admission and discharge information are critical to PACS for improving image routing and storage management algorithms. The design of the interface between the RIS and the PACS database involves the development of some standardization methods. These include the network communication protocol between the two database servers, the language mapping operations, the database result format and the error handling. The implementation of the interface is in two steps. In the first one, a subset of RIS data is automatically transmitted to the PACS database when some relevant events occur in the RIS. In a second phase, the user at the PACS workstation can directly initiate queries to the RIS. The PACS SQL server (UNIX based) sends SQL network requests as ASCII text to the RIS MUMPS database server (VAX based). The RIS server translates the SQL requests to MUMPS, executes the statements and returns ASCII results to the SQL server. We have been able to exchange information between the RIS and the PACS display programs. RIS text reports can be displayed on PACS workstations. RIS information can be used into pre-fetch algorithms.

  5. A PACS archive architecture supported on cloud services.

    Science.gov (United States)

    Silva, Luís A Bastião; Costa, Carlos; Oliveira, José Luis

    2012-05-01

    Diagnostic imaging procedures have continuously increased over the last decade and this trend may continue in coming years, creating a great impact on storage and retrieval capabilities of current PACS. Moreover, many smaller centers do not have financial resources or requirements that justify the acquisition of a traditional infrastructure. Alternative solutions, such as cloud computing, may help address this emerging need. A tremendous amount of ubiquitous computational power, such as that provided by Google and Amazon, are used every day as a normal commodity. Taking advantage of this new paradigm, an architecture for a Cloud-based PACS archive that provides data privacy, integrity, and availability is proposed. The solution is independent from the cloud provider and the core modules were successfully instantiated in examples of two cloud computing providers. Operational metrics for several medical imaging modalities were tabulated and compared for Google Storage, Amazon S3, and LAN PACS. A PACS-as-a-Service archive that provides storage of medical studies using the Cloud was developed. The results show that the solution is robust and that it is possible to store, query, and retrieve all desired studies in a similar way as in a local PACS approach. Cloud computing is an emerging solution that promises high scalability of infrastructures, software, and applications, according to a "pay-as-you-go" business model. The presented architecture uses the cloud to setup medical data repositories and can have a significant impact on healthcare institutions by reducing IT infrastructures.

  6. Monte Carlo Simulations of PAC-Spectra as a General Approach to Dynamic Interactions

    Energy Technology Data Exchange (ETDEWEB)

    Danielsen, Eva; Jorgensen, Lars Elkjaer; Sestoft, Peter [Royal Veterinary and Agricultural University, Department of Mathematics and Physics (Denmark)

    2002-09-15

    Time Dependent Perturbed Angular Correlations of {gamma}-rays (PAC) can be used to study hyperfine interactions of a dynamic nature. However, the exact effect of the dynamic interaction on the PAC-spectrum is sometimes difficult to derive analytically. A new approach based on Monte Carlo simulations is therefore suggested, here implemented as a Fortran 90 program for simulating PAC spectra of dynamic electric field gradients of any origin. The program is designed for the most common experimental condition where the intermediate level has spin 5/2, but the approach can equally well be used for other spin states. Codes for 4 different situations have been developed: (1) Rotational diffusion by jumps; used as a test case. (2) Jumps between two states with different electric field gradients, different lifetimes and different orientations of the electric field gradient principal axes. (3) Relaxation of one state to another. (4) Molecules adhering to a surface with random rotational jumps around the axis perpendicular to the surface. To illustrate how this approach can be used to improve data-interpretation, previously published data on {sup 111m}Cd-plastocyanin and {sup 111}Ag-plastocyanin are re-considered. The strength of this novel approach is its simplicity and generality so that other dynamic processes can easily be included by only adding new program units describing the random process behind the dynamics. The program is hereby made publicly available.

  7. Integrating CAD modules in a PACS environment using a wide computing infrastructure.

    Science.gov (United States)

    Suárez-Cuenca, Jorge J; Tilve, Amara; López, Ricardo; Ferro, Gonzalo; Quiles, Javier; Souto, Miguel

    2017-04-01

    The aim of this paper is to describe a project designed to achieve a total integration of different CAD algorithms into the PACS environment by using a wide computing infrastructure. The aim is to build a system for the entire region of Galicia, Spain, to make CAD accessible to multiple hospitals by employing different PACSs and clinical workstations. The new CAD model seeks to connect different devices (CAD systems, acquisition modalities, workstations and PACS) by means of networking based on a platform that will offer different CAD services. This paper describes some aspects related to the health services of the region where the project was developed, CAD algorithms that were either employed or selected for inclusion in the project, and several technical aspects and results. We have built a standard-based platform with which users can request a CAD service and receive the results in their local PACS. The process runs through a web interface that allows sending data to the different CAD services. A DICOM SR object is received with the results of the algorithms stored inside the original study in the proper folder with the original images. As a result, a homogeneous service to the different hospitals of the region will be offered. End users will benefit from a homogeneous workflow and a standardised integration model to request and obtain results from CAD systems in any modality, not dependant on commercial integration models. This new solution will foster the deployment of these technologies in the entire region of Galicia.

  8. Completion and Testing of PACS SWIR Channel

    Data.gov (United States)

    National Aeronautics and Space Administration — PACS SWIR has important technological innovations that will be necessary to meet the mission requirements for wide FOV, hyperangle capability, high polarimetric...

  9. Positive aspects of caregiving (PAC): scale validation among Chinese dementia caregivers (CG).

    Science.gov (United States)

    Lou, Vivian W Q; Lau, Bobo Hi-Po; Cheung, Karen Siu-Lan

    2015-01-01

    This study validates the psychometric properties of the PAC scale among Hong Kong Chinese informal dementia caregivers. Three hundred and seventy-four caregivers responded to questionnaires including the Chinese version of the PAC scale, Center for Epidemiologic Studies Depression Scale (CES-D), Zarit Burden Interview (ZBI), occurrence of problem behaviors, caregiver bother, caregiver confidence, and self-rated health (SRH). Translation and back translation were conducted in translating the PAC scale. Results of an exploratory principal component analysis (PCA) suggest two components in the 11-item Chinese PAC (C-PAC) scale, namely enriching life and affirming self. C-PAC demonstrates satisfactory reliability. Criteria-related validity of C-PAC is suggested by significant correlations with CES-D, SRH, occurrence of problem behaviors, caregiver bother, and caregiver confidence. Our results support the psychometric properties of C-PAC among Hong Kong Chinese caregivers. This brief measure may help interventionists identify psychological resources of caregivers and capitalize these resources during strength-based interventions. Copyright © 2014. Published by Elsevier Ireland Ltd.

  10. Parents as Agents of Change (PAC in pediatric weight management: The protocol for the PAC randomized clinical trial

    Directory of Open Access Journals (Sweden)

    Ball Geoff D C

    2012-08-01

    Full Text Available Abstract Background There is an urgent need to develop and evaluate weight management interventions to address childhood obesity. Recent research suggests that interventions designed for parents exclusively, which have been named parents as agents of change (PAC approaches, have yielded positive outcomes for managing pediatric obesity. To date, no research has combined a PAC intervention approach with cognitive behavioural therapy (CBT to examine whether these combined elements enhance intervention effectiveness. This paper describes the protocol our team is using to examine two PAC-based interventions for pediatric weight management. We hypothesize that children with obesity whose parents complete a CBT-based PAC intervention will achieve greater reductions in adiposity and improvements in cardiometabolic risk factors, lifestyle behaviours, and psychosocial outcomes than children whose parents complete a psycho-education-based PAC intervention (PEP. Methods/Design This study is a pragmatic, two-armed, parallel, single-blinded, superiority, randomized clinical trial. The primary objective is to examine the differential effects of a CBT-based PAC vs PEP-based PAC intervention on children’s BMI z-score (primary outcome. Secondary objectives are to assess intervention-mediated changes in cardiometabolic, lifestyle, and psychosocial variables in children and parents. Both interventions are similar in frequency of contact, session duration, group facilitation, lifestyle behaviour goals, and educational content. However, the interventions differ insofar as the CBT-based intervention incorporates theory-based concepts to help parents link their thoughts, feelings, and behaviours; these cognitive activities are enabled by group leaders who possess formal training in CBT. Mothers and fathers of children (8–12 years of age; BMI ≥85th percentile are eligible to participate if they are proficient in English (written and spoken and agree for at least

  11. Short history of PACS. Part I: USA

    International Nuclear Information System (INIS)

    Huang, H.K.

    2011-01-01

    This historical review covers the PACS development in the USA during the past 28 years from 1982 to 2010. General historical remarks of PACS and international scene in three stages from infancy, puberty to adolescence are presented. Early PACS development was mostly financed by the federal government including the National Institutes of Health (NIH) and the U.S. Army Medical Research and Materiel Command. PACS evolution went through several stages. The earliest stages included the definition of large-scale PACS, establishment of the DICOM and other standards, the development of some early key PACS related technologies, and PACS implementation strategies. The later stages were in the concept of enterprise PACS, IHE (Integrating the Healthcare Enterprise) workflow profiles, and ePR with image distribution. The current most excited accomplishment is in the development of the new field in medical imaging informatics. This review goes through these stages and events in the USA during these 28 years, whenever an event involved participants from other countries, the contributors are cited.

  12. Short history of PACS. Part I: USA.

    Science.gov (United States)

    Huang, H K

    2011-05-01

    This historical review covers the PACS development in the USA during the past 28 years from 1982 to 2010. General historical remarks of PACS and international scene in three stages from infancy, puberty to adolescence are presented. Early PACS development was mostly financed by the federal government including the National Institutes of Health (NIH) and the U.S. Army Medical Research and Materiel Command. PACS evolution went through several stages. The earliest stages included the definition of large-scale PACS, establishment of the DICOM and other standards, the development of some early key PACS related technologies, and PACS implementation strategies. The later stages were in the concept of enterprise PACS, IHE (Integrating the Healthcare Enterprise) workflow profiles, and ePR with image distribution. The current most excited accomplishment is in the development of the new field in medical imaging informatics. This review goes through these stages and events in the USA during these 28 years, whenever an event involved participants from other countries, the contributors are cited. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

  13. Short history of PACS. Part I: USA

    Energy Technology Data Exchange (ETDEWEB)

    Huang, H.K., E-mail: hkhuang@aol.com [Departments of Radiology and Biomedical Engineering, University of Southern California (United States); Hong Kong Polytechnic University (Hong Kong); Shanghai Institute of Technical Physics, Chinese Academy of Sciences (China)

    2011-05-15

    This historical review covers the PACS development in the USA during the past 28 years from 1982 to 2010. General historical remarks of PACS and international scene in three stages from infancy, puberty to adolescence are presented. Early PACS development was mostly financed by the federal government including the National Institutes of Health (NIH) and the U.S. Army Medical Research and Materiel Command. PACS evolution went through several stages. The earliest stages included the definition of large-scale PACS, establishment of the DICOM and other standards, the development of some early key PACS related technologies, and PACS implementation strategies. The later stages were in the concept of enterprise PACS, IHE (Integrating the Healthcare Enterprise) workflow profiles, and ePR with image distribution. The current most excited accomplishment is in the development of the new field in medical imaging informatics. This review goes through these stages and events in the USA during these 28 years, whenever an event involved participants from other countries, the contributors are cited.

  14. The sorting protein PACS-2 promotes ErbB signalling by regulating recycling of the metalloproteinase ADAM17

    DEFF Research Database (Denmark)

    Dombernowsky, Sarah Louise; Samsøe-Petersen, Jacob; Petersen, Camilla Hansson

    2015-01-01

    are poorly understood. Here, through a functional genome-wide siRNA screen, we identify the sorting protein PACS-2 as a regulator of ADAM17 trafficking and ErbB signalling. PACS-2 loss reduces ADAM17 cell-surface levels and ADAM17-dependent ErbB ligand shedding, without apparent effects on related proteases...

  15. Altered Circadian Food Anticipatory Activity Rhythms in PACAP Receptor 1 (PAC1 Deficient Mice.

    Directory of Open Access Journals (Sweden)

    Jens Hannibal

    Full Text Available Light signals from intrinsically photosensitive retinal ganglion cells (ipRGCs entrain the circadian clock and regulate negative masking. Two neurotransmitters, glutamate and Pituitary Adenylate Cyclase Activating Polypeptide (PACAP, found in the ipRGCs transmit light signals to the brain via glutamate receptors and the specific PACAP type 1 (PAC1 receptor. Light entrainment occurs during the twilight zones and has little effect on clock phase during daytime. When nocturnal animals have access to food only for a few hours during the resting phase at daytime, they adapt behavior to the restricted feeding (RF paradigm and show food anticipatory activity (FAA. A recent study in mice and rats demonstrating that light regulates FAA prompted us to investigate the role of PACAP/PAC1 signaling in the light mediated regulation of FAA. PAC1 receptor knock out (PAC1-/- and wild type (PAC1+/+ mice placed in running wheels were examined in a full photoperiod (FPP of 12:12 h light/dark (LD and a skeleton photoperiod (SPP 1:11:1:11 h L:DD:L:DD at 300 and 10 lux light intensity. Both PAC1-/- mice and PAC1+/+ littermates entrained to FPP and SPP at both light intensities. However, when placed in RF with access to food for 4-5 h during the subjective day, a significant change in behavior was observed in PAC1-/- mice compared to PAC1+/+ mice. While PAC1-/- mice showed similar FAA as PAC1+/+ animals in FPP at 300 lux, PAC1-/- mice demonstrated an advanced onset of FAA with a nearly 3-fold increase in amplitude compared to PAC1+/+ mice when placed in SPP at 300 lux. The same pattern of FAA was observed at 10 lux during both FPP and SPP. The present study indicates a role of PACAP/PAC1 signaling during light regulated FAA. Most likely, PACAP found in ipRGCs mediating non-image forming light information to the brain is involved.

  16. Enterprise imaging and multi-departmental PACS

    Energy Technology Data Exchange (ETDEWEB)

    Bergh, Bjoern [Universitaetsklinikum Heidelberg, Director of Information Technology and Medical Engineering, Heidelberg (Germany)

    2006-12-15

    The aim of this review is to present the status of digital image acquisition and archiving outside of radiology and to describe the technical concepts and possibilities of how a ''radiology'' Picture Archiving and Communication System (PACS) can become a multi-departmental (MD-)PACS. First the principles of system integration technology are explained and illustrated by the description of a typical radiology system integration. Then four types of modality integration approaches are defined: the direct modality integration (Type-I), the integration via DICOM acquisition software (Type-II) the integration via specialised systems either with (Type-III) or without PACS connection (Type-IV). The last section is dedicated to the presentation of the PACS requirements of selected interdisciplinary modality types [Endoscopy, Ultrasound and Electrocardiography (ECG)] and clinical disciplines (Pathology, Dermatology, Ophthalmology and Cardiology), which are then compared with the technical possibilities of a MD-PACS. (orig.)

  17. PAC study of dynamic hyperfine interactions at {sup 111}In-doped Sc{sub 2}O{sub 3} semiconductor and comparison with ab initio calculations

    Energy Technology Data Exchange (ETDEWEB)

    Munoz, E. L., E-mail: munoz@fisica.unlp.edu.ar; Richard, D. [Departamento de Fisica and Instituto de Fisica La Plata (IFLP, CCT La Plata, CONICET) (Argentina); Carbonari, A. W. [Instituto de Pesquisas Energeticas y Nucleares-IPEN-CNEN/SP (Brazil); Errico, L. A.; Renteria, M. [Departamento de Fisica and Instituto de Fisica La Plata (IFLP, CCT La Plata, CONICET) (Argentina)

    2010-04-15

    Time-Differential {gamma}-{gamma} Perturbed-Angular-Correlation (PAC) measurements were performed in {sup 111}In-difussed Sc{sub 2}O{sub 3} polycrystals in order to characterize the electric-field-gradient tensor at {sup 111}Cd nuclei located at the two non-equivalent cation sites of the host lattice. The experimental data were compared with ab initio calculations performed using the Full-Potential Augmented Plane Wave plus local orbital (FP-APW+lo) method in the framework of the Density Functional Theory. The PAC experiments were carried out in air in the temperature range 10-900 K. The spectra present a strong damping below 650 K. This damping is associated with dynamic hyperfine interactions that were analyzed with the perturbation factor proposed by Baeverstam et al.. A model based in the population of impurity levels that are introduced by the Cd probes (supported by FP-APW+lo results) is proposed in order to explain the origin of the observed dynamic interactions.

  18. Integrating organic micropollutant removal into tertiary filtration: Combining PAC adsorption with advanced phosphorus removal.

    Science.gov (United States)

    Altmann, Johannes; Sperlich, Alexander; Jekel, Martin

    2015-11-01

    Direct addition of powdered activated carbon (PAC) to a deep-bed filter was investigated at pilot-scale as a single advanced treatment stage for simultaneous removal of organic micropollutants (OMPs) and phosphorus from secondary effluent. PAC doses of 10-50 mg/L were assessed with regard to their impacts on filter performance and removal of 15 selected OMPs over a period of 18 months. The PAC was effectively retained by the filter and had no negative effect on filter head loss. Filter runtime until particle breakthrough depended mainly on coagulant dose and did not decrease significantly due to the additional PAC load. Removal of suspended solids and phosphorus by coagulation was effective independent of the PAC dose. A PAC dose of 35 mg/L PAC was suitable to remove well-adsorbing OMPs (e.g. carbamazepine, diclofenac) by >80% and medium adsorbing OMPs (e.g. primidone, sulfamethoxazole) by 50-80%. Median removals were 50-80% for well-adsorbing and 30-50% for medium adsorbing OMPs with 20 mg/L PAC. Abatement of all OMPs was low (removal, relevant concentration decreases of certain OMPs (e.g. 4-formylaminoantipyrine) were attributed to biological transformation in the filter. Adsorption onto accumulating PAC in the top layer of the filter bed led to improved OMP adsorption with increasing filter runtime. The comparison of OMP removal in the pilot filter with laboratory adsorption tests demonstrates that batch test results can be applied to estimate adsorptive OMP removal in real applications. Copyright © 2015 Elsevier Ltd. All rights reserved.

  19. Scalability, performance, and fault tolerance of PACS architectures

    Science.gov (United States)

    Blume, Hartwig R.; Prior, Fred W.; di Pierro, Milan C.; Goble, John C.; Lodgberg, Jonas; Kenney, Robert S.; Goeringer, Fred

    1998-07-01

    Three data-base architectures may be distinguished among Picture Archiving and Communication Systems (PACSs): (1) Configurations with logically and physically centralized data- base and file server, (2) systems with physically distributed file servers and a logically centralized data-base, and (3) installations with logically and physically distributed data- bases and file servers. A brief overview of these architectures and their scaleability, performance, and fault- tolerance is given. A PACS for an existing large university hospital is designed for the first as well as the second architecture using given image production data and workflow. We evaluate the fault-tolerance of the two architectures. By modeling the work-flow and employing queuing theory, solutions with practically realizable data transfer requirements are found for both architectures. With today's performance and cost of computers, storage, and information management technologies, the second and third architectures are preferably implemented, depending on the size of the installation. The architectures offer almost unlimited scaleability, very high fault-tolerance, and optimized workflow. We describe a modern commercial PACS that adheres to the open-systems concept and consists of software application programs that run, independent of specific computer and network components, on off-the-shelf hardware and under standard multi-platform operating systems and utilize commercial data-base management systems and network managers. The system is based on the second architecture with multiple islands of functionality, each with servers and archive modules and a physically distributed data-base. Our PACS architecture supports browser technology: Workstations use the data-base to determine the location of needed information and then, through the image browser, mount the appropriate file server for access. The architecture supports a concept similar to domain name server (DNS) directory services on the

  20. PACS in the nuclear medicine service

    International Nuclear Information System (INIS)

    Bitter, F.; Hellwig, D.; Weller, R.; Almasi, L.; Adam, W.E.

    1988-01-01

    A Picture Archiving and Communication System (PACS) is to be understood as a central system in a hospital spanning all services, interconnecting all imaging stations and allowing digital picture archivation. All data of a patient are prepared for direct access. A PAC system is made up of the following components: imaging equipment and data systems, viewing stations (image display), picture communication, storage, archive, connection to hospital information system. The authors explain the requirements to be met by a PACS, its set-up and mode of function, and they system the use. (orig./MG) [de

  1. Improving the performance of an aerobic membrane bioreactor (MBR) treating pharmaceutical wastewater with powdered activated carbon (PAC) addition.

    Science.gov (United States)

    Kaya, Yasemin; Bacaksiz, A Murat; Golebatmaz, Ugur; Vergili, Ilda; Gönder, Z Beril; Yilmaz, Gulsum

    2016-04-01

    In this study, the effects of organic loading rate (OLR) and the addition of powdered activated carbon (PAC) on the performance and membrane fouling of MBR were conducted to treat real pharmaceutical process wastewater. Over 145 days of operation, the MBR system was operated at OLRs ranging from 1 to 2 kg COD m(-3) day(-1) without sludge wasting. The addition of PAC provided an improvement in the flux, despite an increase in the OLR:PAC ratio. The results demonstrated that the hybrid PAC-MBR system maintained a reduced amount of membrane fouling and steadily increased the removal performance of etodolac. PAC addition reduced the deposition of extracellular polymeric substance and organic matter on the membrane surface and resulted an increase in COD removal even at higher OLRs with low PAC addition. Membrane fouling mechanisms were investigated using combined adsorption fouling models. Modified fouling index values and normalized mass transfer coefficient values indicated that predominant fouling mechanism was cake adsorption.

  2. Integration of a clinical trial database with a PACS

    International Nuclear Information System (INIS)

    Van Herk, M

    2014-01-01

    Many clinical trials use Electronic Case Report Forms (ECRF), e.g., from OpenClinica. Trial data is augmented if DICOM scans, dose cubes, etc. from the Picture Archiving and Communication System (PACS) are included for data mining. Unfortunately, there is as yet no structured way to collect DICOM objects in trial databases. In this paper, we obtain a tight integration of ECRF and PACS using open source software. Methods: DICOM identifiers for selected images/series/studies are stored in associated ECRF events (e.g., baseline) as follows: 1) JavaScript added to OpenClinica communicates using HTML with a gateway server inside the hospitals firewall; 2) On this gateway, an open source DICOM server runs scripts to query and select the data, returning anonymized identifiers; 3) The scripts then collects, anonymizes, zips and transmits selected data to a central trial server; 4) Here data is stored in a DICOM archive which allows authorized ECRF users to view and download the anonymous images associated with each event. Results: All integration scripts are open source. The PACS administrator configures the anonymization script and decides to use the gateway in passive (receiving) mode or in an active mode going out to the PACS to gather data. Our ECRF centric approach supports automatic data mining by iterating over the cases in the ECRF database, providing the identifiers to load images and the clinical data to correlate with image analysis results. Conclusions: Using open source software and web technology, a tight integration has been achieved between PACS and ECRF.

  3. Current developments in departmental PACS for ultrasound.

    Science.gov (United States)

    Grenier, L E; Eng, P

    1995-01-01

    1. INTRODUCTION TO DEPARTMENTAL PACS. Full or partial Departmental PACS is generally taken to mean an image management system focused on serving the needs of a specific modality or modality application. It will provide a modality specific means of image acquisition, specialized redisplay of images, distribution, and local long term storage of images. A Departmental PACS can be considered in isolation or as a component in a distributed Radiology PACS which consists of one or more departmental work groups on a back bone, potentially with shared resources. 2. DEPARTMENTAL PACS Issues Implementation of a Departmental PACS requires an in-depth knowledge of departmental clinical practice and work flow in all affected areas in the department, including patient intake, image collection, data routing, retrieval of previous image data, reporting, and long term data management and storage. Optimization of modality specific image display systems requires significant involvement from representative physician users. System architectures and user interfaces must be flexible enough to support the span of variation in clinical practice encountered in the site. A departmental PACS should offer a variety of "open" communications interfaces, both local and wide area, recognizing that outreach efforts are often driven by specific imaging departments. Interfaces to other departmental PAC systems and other information systems must be considered in order to facilitate institutions developing "Best of Breed" PACS systems. As hospitals move toward the integrated electronic medical record, means need to exist for a client process launched from a physician desktop to acquire images and/or reports from a departmental system. At minimum, HIS/RIS interfaces need to be considered to minimize re-keying of data and reduce data entry errors. 3. DESIGN OBJECTIVES FOR ALI ULTRAPACS. The key objectives were to design a product which could function either as a free standing PACS or as a departmental

  4. PACS in the Utrecht University Hospital: final conclusions of the clinical evaluation

    Science.gov (United States)

    Wilmink, J. B.; ter Haar Romeny, Bart M.; Barneveld Binkhuysen, Frits H.; Achterberg, A. J.; Zuiderveld, Karel J.; Calkoen, P.; Kouwenberg, Jef M.

    1990-08-01

    In the past three years, a clinical evaluation of a PACS has been performed in the Utrecht University Hospital as part of the Dutch PACS project. The clinical evaluation focussed on the following aspects: technical evaluation of the prototype PACS equipment coupled to the HIS; diagnostic accuracy studies; studies concerning the impact on the organization of the radiology-department and the referring wards; and cost-savings analysis. Some of the results of these subprojects have already been presented at previous SPIE conferences. In this paper the general condusions are presented about the usefulness of the evaluated PAC-System in the daily routine of radiology department and clinic. By making available the images of radiological examinations fast, complete, reliable and continously on the ward, concrete improvements with regard to the current process could be realized. The possibilities of PACS caused an increasing enthousiasm among the clinicians. By the easier access to all images of their patients during 24 hours/day, they saw more images on the day of the examination and images could be more easily used at consultations of other specialists. The overall conclusion is positive, but a lot of work has to be done to transform PACS from an experimental setup into a routine production system on which a flimless hospital can be based. A complete PACS needs an inteffigent Image Management System, which indudes prefetching algorithms based on data from the Hospital Information System and automated procedures for removing obsolete images from the local buffers in the workstations. As yet PACS is very expensive, and the direct savings in the hospital cannot compensate for the high costs of investment. Possibly PACS can contribute to a shorter stay of patients in the hospital. This will lead to savings for government and health insurance companies and they can be expected to contribute to PAS implementation studies.

  5. Status of the CP-PACS Project

    International Nuclear Information System (INIS)

    Ukawa, A.

    1995-01-01

    The CP-PACS Project, which started in April 1992, is a five-year plan to develop a massively parallel computer for carrying out research in computational physics with primary emphasis on lattice QCD. This article describes the architectural design of the CP-PACS computer, the entire computing system including the front end and mass storage, and results of benchmarks for the expected performance for lattice QCD applications. ((orig.))

  6. Short history of PACS (Part II: Europe)

    International Nuclear Information System (INIS)

    Lemke, Heinz U.

    2011-01-01

    Although the concept of picture archiving and communications systems (PACS) was developed in Europe during the latter part of the 1970s, no working system was completed at that time. The first PACS implementations took place in the United States in the early 1980s, e.g. at Pennsylvania University, UCLA, and Kansas City University. Some more or less successful PACS developments also took place in Europe in the 1980s, particularly in the Netherlands, Belgium, Austria, the United Kingdom, France, Italy, Scandinavia, and Germany. Most systems could be characterized by their focus on a single department, such as radiology or nuclear medicine. European hospital-wide PACS with high visibility evolved in the early 1990s in London (Hammersmith Hospital) and Vienna (SMZO). These were followed during the latter part of the 1990s by approximately 10-20 PACS installations in each of the major industrialized countries of Europe. Wide-area PACS covering several health care institutions in a region are now in the process of being implemented in a number of European countries. Because of limitations of space some countries, for example, Denmark, Finland, Spain, Greece, as well as Eastern European countries, etc. could not be appropriately represented in this paper.

  7. From PACS to Web-based ePR system with image distribution for enterprise-level filmless healthcare delivery.

    Science.gov (United States)

    Huang, H K

    2011-07-01

    The concept of PACS (picture archiving and communication system) was initiated in 1982 during the SPIE medical imaging conference in New Port Beach, CA. Since then PACS has been matured to become an everyday clinical tool for image archiving, communication, display, and review. This paper follows the continuous development of PACS technology including Web-based PACS, PACS and ePR (electronic patient record), enterprise PACS to ePR with image distribution (ID). The concept of large-scale Web-based enterprise PACS and ePR with image distribution is presented along with its implementation, clinical deployment, and operation. The Hong Kong Hospital Authority's (HKHA) integration of its home-grown clinical management system (CMS) with PACS and ePR with image distribution is used as a case study. The current concept and design criteria of the HKHA enterprise integration of the CMS, PACS, and ePR-ID for filmless healthcare delivery are discussed, followed by its work-in-progress and current status.

  8. Experience with high-performance PACS

    Science.gov (United States)

    Wilson, Dennis L.; Goldburgh, Mitchell M.; Head, Calvin

    1997-05-01

    Lockheed Martin (Loral) has installed PACS with associated teleradiology in several tens of hospitals. The PACS that have been installed have been the basis for a shift to filmless radiology in many of the hospitals. the basic structure for the PACS and the teleradiology that is being used is outlined. The way that the PACS are being used in the hospitals is instructive. The three most used areas for radiology in the hospital are the wards including the ICU wards, the emergency room, and the orthopedics clinic. The examinations are mostly CR images with 20 percent to 30 percent of the examinations being CT, MR, and ultrasound exams. The PACS are being used to realize improved productivity for radiology and for the clinicians. For radiology the same staff is being used for 30 to 50 percent more workload. For the clinicians 10 to 20 percent of their time is being saved in dealing with radiology images. The improved productivity stems from the high performance of the PACS that has been designed and installed. Images are available on any workstation in the hospital within less than two seconds, even during the busiest hour of the day. The examination management functions to restrict the attention of any one user to the examinations that are of interest. The examination management organizes the workflow through the radiology department and the hospital, improving the service of the radiology department by reducing the time until the information from a radiology examination is available. The remaining weak link in the PACS system is transcription. The examination can be acquired, read, an the report dictated in much less than ten minutes. The transcription of the dictated reports can take from a few hours to a few days. The addition of automatic transcription services will remove this weak link.

  9. Disaster-hardened imaging POD for PACS

    Science.gov (United States)

    Honeyman-Buck, Janice; Frost, Meryll

    2005-04-01

    operated on emergency power, a limited, but effective number of studies could be performed. However, in a digital department, there is a reliance on the network infrastructure to deliver images to viewing locations. The system developed for our institution uses several imaging PODS, a name we chose because it implied to us a safe, contained environment. Each POD is on both the standard and the emergency power systems. All the vendor equipment that produces images is on a private, stand-alone network controlled either by a simple or a managed switch. Included in each POD is a dry-process DICOM printer that is rarely used during normal operations and a display workstation. One node on the private network is a PACS application processor (AP) with two network interface cards, one for the private network, one for the standard PACS network. During ordinary daily operations, all acquired images pass through this AP and are routed to the PACS archives, web servers, and workstations. However, if the power and network to much of the hospital were to fail, the stand-alone POD could still function. Images are routed to the AP, but cannot forward to the main network. However, they can be routed to the printer and display in the POD. They are also stored on the AP to continue normal routing when the infrastructure is restored. Results: The imaging PODS have been tested in actual disaster testing where the infrastructure was intentionally removed and worked as designed. To date, we have not had to use them in a real-life scenario and we hope we never do, but we feel we have a reasonable level of emergency imaging capability if we ever need it. Conclusions: Our testing indicates our PODS are a viable way to continue medical imaging in the face of an emergency with a major part of our network and electrical infrastructure destroyed.

  10. PACS module image communication at UCLA

    International Nuclear Information System (INIS)

    Stewart, B.K.; Taira, R.K.; Cho, P.S.; Mankovich, N.J.

    1987-01-01

    The advent of the ACR-NEMA digital and communication standard for PACS implementation between imaging, storage and display devices may simplify the networking problems inherent to PACS in the future. However, since the ACR-NEMA interface has not been implemented in manufactured products, the components of a PACS at the present time use various network interface designs, requiring substantial effort in the area of hardware and software integration. Many communication systems are used for the PACS implementation in Pediatric Radiology at UCLA, including baseband, broadband, as well as various parallel-line interface protocols, e.g. GP-IB. A VAX 11/750 minicomputer serves as the host computer for the UCLA Pediatric Radiology PACS system. Communication between the many peripherals take place through the host computer, which acts as the central node. Several communication links have been established, primarily: host computer to other local computers, image processors, various peripherals (digitizers, storage media, etc.) and, of course, to the 512, 1024 and 2048 viewing stations

  11. IHE profiles applied to regional PACS

    International Nuclear Information System (INIS)

    Fernandez-Bayo, Josep

    2011-01-01

    PACS has been widely adopted as an image storage solution that perfectly fits the radiology department workflow and that can be easily extended to other hospital departments. Integrations with other hospital systems, like the Radiology Information System, the Hospital Information System and the Electronic Patient Record are fully achieved but still challenging aims. PACS also creates the perfect environment for teleradiology and teleworking setups. One step further is the regional PACS concept where different hospitals or health care enterprises share the images in an integrated Electronic Patient Record. Among the different solutions available to share images between different hospitals IHE (Integrating the Healthcare Enterprise) organization presents the Cross Enterprise Document Sharing profile (XDS) which allows sharing images from different hospitals even if they have different PACS vendors. Adopting XDS has multiple advantages, images do not need to be duplicated in a central archive to be shared among the different healthcare enterprises, they only need to be indexed and published in a central document registry. In the XDS profile IHE defines the mechanisms to publish and index the images in the central document registry. It also defines the mechanisms that each hospital will use to retrieve those images regardless on the Hospital PACS they are stored.

  12. Chronic exposure of the oligochaete Lumbriculus variegatus to polycyclic aromatic compounds (PACs): bioavailability and effects on reproduction.

    NARCIS (Netherlands)

    Leon Paumen, M.; Stol, P.; ter Laak, T.L.; Kraak, M.H.S.; van Gestel, C.A.M.; Admiraal, W.

    2008-01-01

    This study aimed to monitor PAC availability to the oligochaete Lumbriculus variegatus during 28 days of exposure to spiked sediments, in order to obtain reliable chronic effect concentrations for reproduction. Sediment toxicity tests were performed using three pairs of PAC isomers: two homocyclic

  13. Simulated models of inhomogeneous broadening in perturbed angular correlation spectroscopy (PAC)

    Science.gov (United States)

    Stufflebeam, Michael A.; Hodges, Jeffery A.; Evenson, William E.; Matheson, P.; Zacate, M. O.

    2007-10-01

    All real crystals have defects: missing atoms (vacancies), impurities, atoms out of place, etc. In perturbed angular correlation (PAC), these defects produce damping of the correlation signal in time and broadening of the frequency spectrum. This broadening is termed ``inhomogeneous broadening'' since it is due to the inhomogeneities (i.e. defects) in the crystal. We have simulated PAC spectra for various concentrations (0.1% to 5%) of distant randomly distributed defects plus a near-neighbor vacancy in simple cubic and face-centered cubic crystal structures. For every particular set of defects, the randomly distributed defects and the near-neighbor vacancy together produce a net electric field gradient (EFG), from which we obtain the PAC spectrum. We fit average PAC spectra to study the effects of defect concentration and crystal structure on inhomogeneous broadening as an aid to analyzing experimental data.

  14. PAC Spectrometer for Condensed Matter Investigation

    CERN Document Server

    Brudanin, V B; Kochetov, O I; Korolev, N A; Milanov, M; Ostrovsky, I V; Pavlov, V N; Salamatin, A V; Timkin, V V; Velichkov, A I; Fomicheva, L N; Tsvyaschenko, A V; Akselrod, Z Z

    2005-01-01

    A four-detector spectrometer of perturbed angular $\\gamma \\gamma $ correlations is developed for investigation of hyperfine interactions in condensed matter. It allows measurements with practically any types of detectors. A unique circuit design involving a specially developed Master PAC unit combined with a computer allows a substantially higher efficiency, reduced setup time and simpler operation in comparison with traditional PAC spectrometers. A cryostat and a high-temperature oven allow measurements in the temperature range from 120 to 1300 K. An encased electromagnet makes it possible to generate a magnetic field up to 2 T on a sample. The measurement system includes a press with a specially designed high-pressure chamber allowing on-line PAC measurements in samples under pressure up to 60 GPa.

  15. A Layered Approach To Pacs Network Architecture

    Science.gov (United States)

    Hegde, Shankar S.; Prewitt, Judith M.

    1984-08-01

    Although the functions performed by the different nodes on the PACS network are many, it is possible to formulate a minimum set of service primitives such that the application software residing at the nodes can utilize those primitives to perform the functions. These primitives define the framework for the communication interface. The question of how these primitives fit into the concept of a layered network architecture is explored in this paper. The OSI model as applicable to the PACS network is described, the areas that need standardization are briefly mentioned, and the ongoing standardization efforts are addressed from the OSI perspective.

  16. [PACS-based endoscope image acquisition workstation].

    Science.gov (United States)

    Liu, J B; Zhuang, T G

    2001-01-01

    A practical PACS-based Endoscope Image Acquisition Workstation is here introduced. By a Multimedia Video Card, the endoscope video is digitized and captured dynamically or statically into computer. This workstation realizes a variety of functions such as the endoscope video's acquisition and display, as well as the editing, processing, managing, storage, printing, communication of related information. Together with other medical image workstation, it can make up the image sources of PACS for hospitals. In addition, it can also act as an independent endoscopy diagnostic system.

  17. PACS: Do clinical users benefit from it as a training adjunct?

    Directory of Open Access Journals (Sweden)

    J van Heerden

    2011-05-01

    Full Text Available Background. Over the past four years, Steve Biko Academic Hospital has been in the process of implementing and refining the use of a picture archiving and communications system (PACS. As part of a post-implementation refining process, it is necessary to evaluate user-perceptions in order to improve on good system qualities and correct flaws. Aim. The aim of this study was to assess whether medical clinicians perceived PACS as a positive adjunct to training and teaching opportunities – specifically those opportunities related to radiological image viewing and interpretation as part of patient case discussions. Method. Standardised questionnaires with ‘free text’ and ‘option selection’ questions were distributed to clinicians who, as part of their training, rotated at Steve Biko Academic Hospital (where a PACS is in place as well as other teaching hospitals without a PACS. Between February 2009 and May 2009, approximately 400 questionnaires were distributed. As a result of constant academic rotations, leave schedules of medical staff and posts vacated, questionnaires could not be distributed to the entire target population that was estimated to be in the region of 550 medical clinicians (comprising senior medical students, interns, medical officers, registrars and consultants. Of the 400 questionnaires distributed, 189 completed questionnaires were returned. Completion of the questionnaires was voluntary and anonymous. Results and conclusion. Although a PACS relates specifically to the archiving and retrieval of radiological images and reports, it became clear from the feedback received from medical clinicians (who are ward-based, theatre-based or clinic-based users of a digital system that many other factors, such as lack of adequate hardware and sub-optimal personal IT proficiency, contributed to some of the negative PACS-related perceptions and ‘lost teaching opportunities’ reported. Negative comments specifically related to PACS

  18. PacMYBA, a sweet cherry R2R3-MYB transcription factor, is a positive regulator of salt stress tolerance and pathogen resistance.

    Science.gov (United States)

    Shen, Xinjie; Guo, Xinwei; Guo, Xiao; Zhao, Di; Zhao, Wei; Chen, Jingsheng; Li, Tianhong

    2017-03-01

    Plant R2R3-MYB transcription factors play crucial roles in stress responses. We previously isolated a R2R3-MYB homolog from sweet cherry cv. Hong Deng, designated PacMYBA (GenBank accession No. KF974774). To explore the role of PacMYBA in the plant stress response, we heterologously expressed PacMYBA in transgenic Arabidopsis thaliana plants. In a previous study, we demonstrated that PacMYBA is mainly localized to the nucleus and could be induced by abscisic acid (ABA). Analysis of the promoter sequence of PacMYBA revealed that it contains several stress-related cis-elements. QPCR results showed that PacMYBA is induced by salt, salicylic (SA), and jasmonic acid (JA) in sweet cherry leaves. Transgenic Arabidopsis plants heterologously expressing PacMYBA exhibited enhanced salt-tolerance and increased resistance to Pseudomonas syringe pv. tomato (Pst) DC3000 infection. Overexpression of PacMYBA decreased the osmotic potential (OP), increased the free proline content, and increased the peroxidase content in transgenic Arabidopsis plants. Furthermore, overexpression of PacMYBA also affected the expression levels of salt stress- and pathogen defense-related genes in the transgenic plants. These results indicate that PacMYBA is a positive regulator of salt stress tolerance and pathogen resistance. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  19. PACS spectroscopy of OH/IR stars

    NARCIS (Netherlands)

    Lombaert, R.; de Vries, B.L.; Decin, L.; Blommaert, J.A.D.L.; Royer, Pierre; De Beck, E.; de Koter, A.; Waters, L.B.F.M.

    2011-01-01

    Observations of high-excitation molecular emission lines can greatly increase our understanding of AGB winds, as they trace the innermost regions of the circumstellar envelope. The PACS spectrometer on-board the Herschel Space Telescope1, provides for the first time the spectral resolution and

  20. Merits of usability testing for PACS selection

    NARCIS (Netherlands)

    Jorritsma, Wiard; Cnossen, Fokie; van Ooijen, Peter M. A.

    Objectives: To compare the usability of different Picture Archiving and Communication System (PACS) workstations, determine whether a usability test has added value with respect to the traditional way of comparing PACSs based on functional requirements, and to evaluate the appropriateness of a

  1. [The design and realization of Web-view PACS browser].

    Science.gov (United States)

    Yu, Pei-liang; Ye, Zhi-qian

    2006-05-01

    This article analyses the system structure and realization model of Web-view PACS browser in combination with the characteristic of PACS, and presents the realizing process of the web-view PACS browser using JSP mode and B/S model.

  2. Picture archiving and communications systems (PACS): an introduction

    International Nuclear Information System (INIS)

    Schwartz, L.H.

    2001-01-01

    Picture Archiving and Communications Systems (PACS) has revolutionized the practice of radiology. PACS consist of a variety of electronic/computer components, and the connectivity between these components. PACS is an efficient means to transmit, store, retrieve and digitally display medical images

  3. A-Type Cranberry Proanthocyanidins Inhibit the RANKL-Dependent Differentiation and Function of Human Osteoclasts

    Directory of Open Access Journals (Sweden)

    Amy B. Howell

    2011-03-01

    Full Text Available This study investigated the effect of A-type cranberry proanthocyanidins (AC-PACs on osteoclast formation and bone resorption activity. The differentiation of human pre-osteoclastic cells was assessed by tartrate-resistant acid phosphatase (TRAP staining, while the secretion of interleukin-8 (IL-8 and matrix metalloproteinases (MMPs was measured by ELISA. Bone resorption activity was investigated by using a human bone plate coupled with an immunoassay that detected the release of collagen helical peptides. AC-PACs up to 100 µg/mL were atoxic for osteoclastic cells. TRAP staining evidenced a dose-dependent inhibition of osteoclastogenesis. More specifically, AC-PACs at 50 µg/mL caused a 95% inhibition of RANKL-dependent osteoclast differentiation. This concentration of AC-PACs also significantly increased the secretion of IL-8 (6-fold and inhibited the secretion of both MMP-2 and MMP-9. Lastly, AC-PACs (10, 25, 50 and 100 µg/ml affected bone degradation mediated by mature osteoclasts by significantly decreasing the release of collagen helical peptides. This study suggests that AC-PACs can interfere with osteoclastic cell maturation and physiology as well as prevent bone resorption. These compounds may be considered as therapeutic agents for the prevention and treatment of periodontitis.

  4. Pattern mining of user interaction logs for a post-deployment usability evaluation of a radiology PACS client.

    Science.gov (United States)

    Jorritsma, Wiard; Cnossen, Fokie; Dierckx, Rudi A; Oudkerk, Matthijs; van Ooijen, Peter M A

    2016-01-01

    To perform a post-deployment usability evaluation of a radiology Picture Archiving and Communication System (PACS) client based on pattern mining of user interaction log data, and to assess the usefulness of this approach compared to a field study. All user actions performed on the PACS client were logged for four months. A data mining technique called closed sequential pattern mining was used to automatically extract frequently occurring interaction patterns from the log data. These patterns were used to identify usability issues with the PACS. The results of this evaluation were compared to the results of a field study based usability evaluation of the same PACS client. The interaction patterns revealed four usability issues: (1) the display protocols do not function properly, (2) the line measurement tool stays active until another tool is selected, rather than being deactivated after one use, (3) the PACS's built-in 3D functionality does not allow users to effectively perform certain 3D-related tasks, (4) users underuse the PACS's customization possibilities. All usability issues identified based on the log data were also found in the field study, which identified 48 issues in total. Post-deployment usability evaluation based on pattern mining of user interaction log data provides useful insights into the way users interact with the radiology PACS client. However, it reveals few usability issues compared to a field study and should therefore not be used as the sole method of usability evaluation. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  5. Future trends in picture archiving and communication system (PACS)

    Science.gov (United States)

    Al-Hajeri, Mona; Clarke, Malcolm

    2015-03-01

    Objective: This research investigates the needs and opinions of radiologists on the use of enhanced information technologies and approaches to improve the functionality of Picture Archiving and Communication Systems (PACS). Method: Six interviews were conducted in the main governmental hospital in Kuwait (AL-Sabah Hospital) with radiologists, including two senior radiologists, two junior radiologists, and two trainee radiologists undertaking the Irish radiology board. Results: The radiologists identified a number of limitations that exist in current PACS and requirements to enhance usability and functionality. However, it was the case that some of the radiologists had little knowledge about the advanced trends in PACS. Four themes emerged from the thematic analysis of the data: (1) limitations of traditional PACS; (2) Features and requirements that can increase PACS functionality; (3) web based solutions of PACS; (4) PACS in mobile phones. Conclusion: It is widely recognized that PACS has limitations. This research has identified themes that, when incorporated, will enhance the functionality of PACS and provide better quality clinical practice. This research has determined the important future trends of PACS. Primarily web based solutions and use in mobile phones. The findings from this research can be used as recommendations to vendors, for product development and medical institutes to consider when undertaking implementation of PACS and training future radiologists.

  6. Deletion of pH Regulator pac-3 Affects Cellulase and Xylanase Activity during Sugarcane Bagasse Degradation by Neurospora crassa

    Science.gov (United States)

    Campos Antoniêto, Amanda Cristina; Ramos Pedersoli, Wellington; dos Santos Castro, Lílian; da Silva Santos, Rodrigo; Cruz, Aline Helena da Silva; Nogueira, Karoline Maria Vieira; Silva-Rocha, Rafael; Rossi, Antonio

    2017-01-01

    Microorganisms play a vital role in bioethanol production whose usage as fuel energy is increasing worldwide. The filamentous fungus Neurospora crassa synthesize and secrete the major enzymes involved in plant cell wall deconstruction. The production of cellulases and hemicellulases is known to be affected by the environmental pH; however, the regulatory mechanisms of this process are still poorly understood. In this study, we investigated the role of the pH regulator PAC-3 in N. crassa during their growth on sugarcane bagasse at different pH conditions. Our data indicate that secretion of cellulolytic enzymes is reduced in the mutant Δpac-3 at alkaline pH, whereas xylanases are positively regulated by PAC-3 in acidic (pH 5.0), neutral (pH 7.0), and alkaline (pH 10.0) medium. Gene expression profiles, evaluated by real-time qPCR, revealed that genes encoding cellulases and hemicellulases are also subject to PAC-3 control. Moreover, deletion of pac-3 affects the expression of transcription factor-encoding genes. Together, the results suggest that the regulation of holocellulase genes by PAC-3 can occur as directly as in indirect manner. Our study helps improve the understanding of holocellulolytic performance in response to PAC-3 and should thereby contribute to the better use of N. crassa in the biotechnology industry. PMID:28107376

  7. Tratamento da pneumonia adquirida na comunidade (PAC)

    OpenAIRE

    Celso Nakagawa

    2007-01-01

    TRATAMENTO ESPECÍFICO PARA AGENTES ETIOLÓGICOS DA PAC Streptococcus pneumoniae - Sensível: Amoxicilina, cefalosporina ou macrolídeo. - Resistência intermediária: Amoxicilina 500 mg, 3x/dia ou cefuroxima 500 mg, 2x/dia. - Altamente resistente: Cefotaxima 1 gIV a cada 8 horas, cefotriaxona 1 g IV a cada 24 horas, Penecilina G 2 milhões a cada 4 horas ou fluoroquinolona respiratória.

  8. A role for PacMYBA in ABA-regulated anthocyanin biosynthesis in red-colored sweet cherry cv. Hong Deng (Prunus avium L.).

    Science.gov (United States)

    Shen, Xinjie; Zhao, Kai; Liu, Linlin; Zhang, Kaichun; Yuan, Huazhao; Liao, Xiong; Wang, Qi; Guo, Xinwei; Li, Fang; Li, Tianhong

    2014-05-01

    The MYB transcription factors and plant hormone ABA have been suggested to play a role in fruit anthocyanin biosynthesis, but supporting genetic evidence has been lacking in sweet cherry. The present study describes the first functional characterization of an R2R3-MYB transcription factor, PacMYBA, from red-colored sweet cherry cv. Hong Deng (Prunus avium L.). Transient promoter assays demonstrated that PacMYBA physically interacted with several anthocyanin-related basic helix-loop-helix (bHLH) transcription factors to activate the promoters of PacDFR, PacANS and PacUFGT, which are thought to be involved in anthocyanin biosynthesis. Furthermore, the immature seeds of transgenic Arabidopsis plants overexpressing PacMYBA exhibited ectopic pigmentation. Silencing of PacMYBA, using a Tobacco rattle virus (TRV)-induced gene silencing technique, resulted in sweet cherry fruit that lacked red pigment. ABA treatment significantly induced anthocyanin accumulation, while treatment with the ABA biosynthesis inhibitor nordihydroguaiaretic acid (NDGA) blocked anthocyanin production. PacMYBA expression peaked after 2 h of pre-incubation in ABA and was 15.2-fold higher than that of sweet cherries treated with NDGA. The colorless phenotype was also observed in the fruits silenced in PacNCED1, which encodes a key enzyme in the ABA biosynthesis pathway. The endogenous ABA content as well as the transcript levels of six structural genes and PacMYBA in PacNCED1-RNAi (RNA interference) fruit were significantly lower than in the TRV vector control fruit. These results suggest that PacMYBA plays an important role in ABA-regulated anthocyanin biosynthesis and ABA is a signal molecule that promotes red-colored sweet cherry fruit accumulating anthocyanin.

  9. Investment alternative: the status quo or PACS?

    Science.gov (United States)

    Vanden Brink, John A.; Cywinski, Jozef K.

    1990-08-01

    While the cost of Picture Archiving and Communication Systems (PACS) can be substantial, the cost of continuing with present manual methods may become prohibitive in growing departments as the need for additional space and personnel (both technical and professional) to meet the increasing requirements for all image management activities continues to grow. This will occur simultaneously with increasing pressures on problems of the present system, i.e., lost films, lost revenues, delayed reporting and longer diagnostic cycle times. Present methods of image archiving communication and management i.e. the relationship of procedure volume to VFE requirements for professional and technical personnel, costs of film, film storage space, and other performance factors are analyzed based on the database created by the Technology Marketing Group (TMG) computerized cost analysis model applied to over 50 US hospitals. Also, the model is used to provide the projected cost of present methods of film management for an average US 400 +bed hospital based on ten year growth rate assumptions. TMG PACS Tracking data provides confirmation of staffmg pattern correlation to procedure volume. The data presented in the paper provides a basis for comparing the investment in maintaining the status quo to an investment in PACS.

  10. The development and validation of the Physical Appearance Comparison Scale-Revised (PACS-R).

    Science.gov (United States)

    Schaefer, Lauren M; Thompson, J Kevin

    2014-04-01

    The Physical Appearance Comparison Scale (PACS; Thompson, Heinberg, & Tantleff, 1991) was revised to assess appearance comparisons relevant to women and men in a wide variety of contexts. The revised scale (Physical Appearance Comparison Scale-Revised, PACS-R) was administered to 1176 college females. In Study 1, exploratory factor analysis and parallel analysis using one half of the sample suggested a single factor structure for the PACS-R. Study 2 utilized the remaining half of the sample to conduct confirmatory factor analysis, item analysis, and to examine the convergent validity of the scale. These analyses resulted in an 11-item measure that demonstrated excellent internal consistency and convergent validity with measures of body satisfaction, eating pathology, sociocultural influences on appearance, and self-esteem. Regression analyses demonstrated the utility of the PACS-R in predicting body satisfaction and eating pathology. Overall, results indicate that the PACS-R is a reliable and valid tool for assessing appearance comparison tendencies in women. Copyright © 2014. Published by Elsevier Ltd.

  11. A dynamic approach to dependability studies

    International Nuclear Information System (INIS)

    Labeau, P.E.

    2008-01-01

    Dependability studies have now become an important part of the performance management of industrial plants. These last decades, several methods have been proposed and widely used for the analysis of systems of components subject to degradation and failure. These methods are based either on Boolean representations (for example, event trees/fault trees), or on discrete-state models (Markovian reliability, Petri nets, Bayesian networks...). However, the underlying, inherently continuous, physical processes have scarcely been accounted for, at least in an integrated fashion, in dependability studies. This paper first describes, through simple cases, the limitations of discrete approaches and the need of hybrid, discrete-continuous methods. It then summarizes the main concepts of dynamic reliability. Finally, some possible application domains are presented, as well as challenges that still need to be tackled to favour the diffusion of this approach among industrial circles. (author)

  12. Role of pacs in an integrated communication system

    International Nuclear Information System (INIS)

    Thompson, B.G.; Creasy, J.L.; Johnston, R.E.; Parrish, D.; Scatliff, J.H.

    1986-01-01

    An integrated computer-based communications system uses multiple computers for the high speed transmission, storage, enhancement and display for medical information. Interconnected by a network such as coaxial and fiberoptic cables or microwave stations, the system would provide integrated communications throughout a satellite medical environment. As the availability of proven PACS components becomes a commercial reality, migratory expansion of PACS within the radiology clinical, educational and research areas will be possible. When the PACS is integrated with hospital, radiology and medical school information systems it provides the image component of a total medical information system. Current PACS efforts are on a research basis including the development of prototype systems. This paper provides an overview of implementation strategies. Issues to be discussed include PACS research objectives, typical implementation methods, and a review of interactions between PACS and radiology information systems (RIS) and hospital information systems

  13. Benchmark test of CP-PACS for lattice QCD

    International Nuclear Information System (INIS)

    Yoshie, Tomoteru

    1996-01-01

    The CP-PACS is a massively parallel computer dedicated for calculations in computational physics and will be in operation in the spring of 1996 at Center for Computational Physics, University of Tsukuba. In this paper, we describe the architecture of the CP-PACS and report the results of the estimate of the performance of the CP-PACS for typical lattice QCD calculations. (author)

  14. Current status of the UCSF second-generation PACS

    Science.gov (United States)

    Huang, H. K.; Arenson, Ronald L.; Wong, Albert W. K.; Bazzill, Todd M.; Lou, Shyhliang A.; Andriole, Katherine P.; Wang, Jun; Zhang, Jianguo; Wong, Stephen T. C.

    1996-05-01

    This paper describes the current status of the second generation PACS at UCSF commenced in October 1992. The UCSF PACS is designed in-house as a hospital-integrated PACS based on an open architecture concept using industrial standards including UNIX operating system, C programming language, X-Window user interface, TCP/IP communication protocol, DICOM 3.0 image standard and HL7 health data format. Other manufacturer's PACS components which conform with these standards can be easily integrated into the system. Relevant data from HIS and RIS is automatically incorporated into the PACS using HL7 data format and TCP/IP communication protocol. The UCSF system also takes advantage of state-of-the-art communication, storage, and software technologies in ATM, multiple storage media, automatic programming, multilevel processes for a better cost-performance system. The primary PACS network is the 155 Mbits/sec OC3 ATM with the Ethernet as the back-up. The UCSF PACS also connects Mt. Zion Hospital and San Francisco VA Medical Center in the San Francisco Bay area via an ATM wide area network with a T1 line as the back-up. Currently, five MR and five CT scanners from multiple sites, two computed radiography systems, two film digitizers, one US PACS module, the hospital HIS and the department RIS have been connected to the PACS network. The image data is managed by a mirrored database (Sybase). The PACS controller, with its 1.3 terabyte optical disk library, acquires 2.5 gigabytes digital data daily. Four 2K, five, 1,600-line multiple monitor display workstations are on line in neuroradiology, pediatric radiology and intensive care units for clinical use. In addition, the PACS supports over 100 Macintosh users in the department and selected hospital sites for both images and textual retrieval through a client/server mechanism. We are also developing a computation and visualization node in the PACS network for advancing radiology research.

  15. Managed PACS operation with an automatic monitoring tool

    Science.gov (United States)

    Zhang, Jianguo; Han, Ruolin; Wu, Dongqing; Zhang, Xiaoyan; Zhuang, Jun; Feng, Jie; Wang, Mingpeng; Zhang, Guozhen; Wang, Cuanfu

    2002-05-01

    Huadong hospital in Shanghai with 800 beds provides health care services for inpatients and outpatients, as well as special senior and VIP patients. In order to move to digital imaging based radiology practice, and also provide better intra-hospital consultation services for senior and VIP patients, we started to implement PACS for hospital wide services from 1999, and also designed and developed an automatic monitoring system (AMS) to monitor and control PACS operation and dataflow to decrease the total cost of ownership for PACS operation. We installed the AMS on top of the Huadong Hospital PACS in the May of 2001. The installation was painless, did not interrupt the normal PACS operation, and took only one month. The PACS administrators with the AMS can now monitor and control the entire PACS operation in real time, and also track patient and image data flow automatically. These features make administrators take proper action even before user's complaint if any failure happened in any PACS component or process, they reduce the size of the management team, and decrease total cost of PACS ownership.

  16. Process development and fabrication for sphere-pac fuel rods

    International Nuclear Information System (INIS)

    Welty, R.K.; Campbell, M.H.

    1981-06-01

    Uranium fuel rods containing sphere-pac fuel have been fabricated for in-reactor tests and demonstrations. A process for the development, qualification, and fabrication of acceptable sphere-pac fuel rods is described. Special equipment to control fuel contamination with moisture or air and the equipment layout needed for rod fabrication is described and tests for assuring the uniformity of the fuel column are discussed. Fuel retainers required for sphere-pac fuel column stability and instrumentation to measure fuel column smear density are described. Results of sphere-pac fuel rod fabrication campaigns are reviewed and recommended improvements for high throughput production are noted

  17. The impact of PACS on clinician work practices in the intensive care unit: a systematic review of the literature.

    Science.gov (United States)

    Hains, Isla M; Georgiou, Andrew; Westbrook, Johanna I

    2012-01-01

    To assess evidence of the impact of Picture Archiving and Communication Systems (PACS) on clinicians' work practices in the intensive care unit (ICU). We searched Medline, Pre-Medline, CINAHL, Embase, and the SPIE Digital Library databases for English-language publications between 1980 and September 2010 using Medical Subject Headings terms and keywords. Eleven studies from the USA and UK were included. All studies measured aspects of time associated with the introduction of PACS, namely the availability of images, the time a physician took to review an image, and changes in viewing patterns. Seven studies examined the impact on clinical decision-making, with the majority measuring the time to image-based clinical action. The effect of PACS on communication modes was reported in five studies. PACS can impact on clinician work practices in three main areas. Most of the evidence suggests an improvement in the efficiency of work practices. Quick image availability can impact on work associated with clinical decision-making, although the results were inconsistent. PACS can change communication practices, particularly between the ICU and radiology; however, the evidence base is insufficient to draw firm conclusions in this area. The potential for PACS to impact positively on clinician work practices in the ICU and improve patient care is great. However, the evidence base is limited and does not reflect aspects of contemporary PACS technology. Performance measures developed in previous studies remain relevant, with much left to investigate to understand how PACS can support new and improved ways of delivering care in the intensive care setting.

  18. Clinical experience with PACS: Digital radiology

    International Nuclear Information System (INIS)

    Hruby, W.; Mosser, H.; Urban, M.; Krampla, W.; Ammann, M.; Mayrhofer, R.; Kaissas, K.

    1994-01-01

    We present our experience during the first 21 months of using hospital-wide network technology and digital archiving in connection with digital radiology in the Radiology Department at the SMZO/Danube hospital in Vienna. This means digital generation, archiving and distribution of radiographs as well as monitor reporting embedded in HIS and RIS. The clinical use of PACS demands full integration of all subsystems and modalities in a digital way, as was first realized at the Danube Hospital. With this approach, a reduction in radiation dose, improved communication and thus a reduction in the length of hospital stay and health care cost are attained. (orig.) [de

  19. REVIEW ARTICLE REVI REVI Talking PACS: Part 1 – What is PACS?

    African Journals Online (AJOL)

    tions of four parts: digital imaging equipment,. PACS (Picture Archiving and Communication. System), RIS .... Mbyte/s (8 bits = 1 byte) thus about 12.5 Mbytes per second. The communication speed on a specific network is determined ... example of a WAN is the Internet. WANs are used to connect local area. Fig. 2. This is a ...

  20. Alternative Splicing of the Pituitary Adenylate Cyclase-Activating Polypeptide Receptor PAC1: Mechanisms of Fine Tuning of Brain Activity

    Directory of Open Access Journals (Sweden)

    Janna eBlechman

    2013-05-01

    Full Text Available Alternative splicing of the precursor mRNA encoding for the neuropeptide receptor PAC1/ADCYAP1R1 generates multiple protein products that exhibit pleiotropic activities. Recent studies in mammals and zebrafish have implicated some of these splice isoforms in control of both cellular and body homeostasis. Here, we review the regulation of PAC1 splice variants and their underlying signal transduction and physiological processes in the nervous system.

  1. Increased platelet activation in early symptomatic versus asymptomatic carotid stenosis and relationship with microembolic status: Results from the Platelets And Carotid Stenosis (PACS) Study.

    LENUS (Irish Health Repository)

    Kinsella, Ja

    2013-04-26

    BACKGROUND: Cerebral microembolic signals (MES) may predict increased stroke risk in carotid stenosis. However, the relationship between platelet counts or platelet activation status and MES in symptomatic versus asymptomatic carotid stenosis has not been comprehensively assessed. SETTING: University teaching hospitals. METHODS: This prospective, pilot observational study assessed platelet counts and platelet activation status, and the relationship between platelet activation and MES in asymptomatic versus early (≤4 weeks after TIA\\/stroke) and late phase (≥3 months) symptomatic moderate or severe (≥50%) carotid stenosis patients. Full blood count measurements were performed, and whole blood flow cytometry was used to quantify platelet surface activation marker expression (CD62P and CD63) and circulating leucocyte-platelet complexes. Bilateral simultaneous transcranial Doppler ultrasound monitoring of the middle cerebral arteries was performed for 1 hour to classify patients as MES-positive or MES-negative. RESULTS: Data from 31 asymptomatic patients were compared with 46 symptomatic patients in the early phase, and 35 of these patients followed up to the late phase after symptom onset. The median platelet count (211 vs. 200 x 10(9) \\/L; p=0.03) and the median% lymphocyte-platelet complexes were higher in early symptomatic than asymptomatic patients (2.8 vs. 2.4%, p=0.001). The% lymphocyte-platelet complexes was higher in early symptomatic than asymptomatic patients with ≥70% carotid stenosis (p=0.0005), and in symptomatic patients recruited within 7 days of symptom onset (p=0.028). Complete TCD data were available in 25 asymptomatic and 31 early phase symptomatic, and 27 late phase symptomatic patients. 12% of asymptomatic versus 32% of early phase symptomatic (p=0.02) and 19% of late phase symptomatic patients (p=0.2) were MES-positive. Early symptomatic MES-negative patients had a higher% lymphocyte-platelet complexes than asymptomatic MES

  2. Handling qualities of a wide-body transport airplane utilizing Pitch Active Control Systems (PACS) for relaxed static stability application

    Science.gov (United States)

    Grantham, William D.; Person, Lee H., Jr.; Brown, Philip W.; Becker, Lawrence E.; Hunt, George E.; Rising, J. J.; Davis, W. J.; Willey, C. S.; Weaver, W. A.; Cokeley, R.

    1985-01-01

    Piloted simulation studies have been conducted to evaluate the effectiveness of two pitch active control systems (PACS) on the flying qualities of a wide-body transport airplane when operating at negative static margins. These two pitch active control systems consisted of a simple 'near-term' PACS and a more complex 'advanced' PACS. Eight different flight conditions, representing the entire flight envelope, were evaluated with emphasis on the cruise flight conditions. These studies were made utilizing the Langley Visual/Motion Simulator (VMS) which has six degrees of freedom. The simulation tests indicated that (1) the flying qualities of the baseline aircraft (PACS off) for the cruise and other high-speed flight conditions were unacceptable at center-of-gravity positions aft of the neutral static stability point; (2) within the linear static stability flight envelope, the near-term PACS provided acceptable flying qualities for static stabilty margins to -3 percent; and (3) with the advanced PACS operative, the flying qualities were demonstrated to be good (satisfactory to very acceptable) for static stabilty margins to -20 percent.

  3. Photo-dynamics of the lyophilized photo-activated adenylate cyclase NgPAC2 from the amoeboflagellate Naegleria gruberi NEG-M strain

    Energy Technology Data Exchange (ETDEWEB)

    Penzkofer, A., E-mail: alfons.penzkofer@physik.uni-regensburg.de [Fakultät für Physik, Universität Regensburg, Universitätsstrasse 31, D-93053 Regensburg (Germany); Tanwar, M.; Veetil, S.K.; Kateriya, S. [Department of Biochemistry, University of Delhi South Campus, Benito Juarez Road, New Delhi 110021 (India); Stierl, M.; Hegemann, P. [Institut für Biologie/Experimentelle Biophysik, Humboldt Universität zu Berlin, Invalidenstrasse 42, D-10115 Berlin (Germany)

    2013-09-23

    Highlights: • Lyophilizing of NgPAC2 from Naegleria gruberi caused loss of BLUF domain activity. • Photo-induced tyrosine to flavin electron transfer in lyophilized NgPAC2. • Photo-induced Tyr–Tyr cross-linking to o,o′-dityrosine in lyophilized NgPAC2. • Photo-induced partial flavin cofactor reduction in lyophilized NgPAC2. • Two NgPAC2 conformations with fast and slow photo-induced electron transfer. - Abstract: The absorption and emission spectroscopic behavior of lyophilized photo-activated adenylate cyclase NgPAC2 from the amoeboflagellate Naegleria gruberi NEG-M strain consisting of a BLUF domain (BLUF = Blue Light sensor Using Flavin) and a cyclase homology domain was studied in the dark, during blue-light exposure and after blue-light exposure at a temperature of 4 °C. The BLUF domain photo-cycle dynamics observed for snap-frozen NgPAC2 was lost by lyophilization (no signaling state formation with flavin absorption red-shift). Instead, blue-light photo-excitation of lyophilized NgPAC2 caused sterically restricted Tyr–Tyr cross-linking (o,o′-ditysosine formation) and partial flavin cofactor reduction.

  4. Photo-dynamics of the lyophilized photo-activated adenylate cyclase NgPAC2 from the amoeboflagellate Naegleria gruberi NEG-M strain

    International Nuclear Information System (INIS)

    Penzkofer, A.; Tanwar, M.; Veetil, S.K.; Kateriya, S.; Stierl, M.; Hegemann, P.

    2013-01-01

    Highlights: • Lyophilizing of NgPAC2 from Naegleria gruberi caused loss of BLUF domain activity. • Photo-induced tyrosine to flavin electron transfer in lyophilized NgPAC2. • Photo-induced Tyr–Tyr cross-linking to o,o′-dityrosine in lyophilized NgPAC2. • Photo-induced partial flavin cofactor reduction in lyophilized NgPAC2. • Two NgPAC2 conformations with fast and slow photo-induced electron transfer. - Abstract: The absorption and emission spectroscopic behavior of lyophilized photo-activated adenylate cyclase NgPAC2 from the amoeboflagellate Naegleria gruberi NEG-M strain consisting of a BLUF domain (BLUF = Blue Light sensor Using Flavin) and a cyclase homology domain was studied in the dark, during blue-light exposure and after blue-light exposure at a temperature of 4 °C. The BLUF domain photo-cycle dynamics observed for snap-frozen NgPAC2 was lost by lyophilization (no signaling state formation with flavin absorption red-shift). Instead, blue-light photo-excitation of lyophilized NgPAC2 caused sterically restricted Tyr–Tyr cross-linking (o,o′-ditysosine formation) and partial flavin cofactor reduction

  5. Time-dependent studies of multiphoton processes

    International Nuclear Information System (INIS)

    Kulander, K.C.; Schafer, K.J.; Krause, J.L.

    1992-01-01

    Interest in intense-field laser-atom interactions has undergone very rapid growth over the past decade due to a number of very surprising observations made during short-pulse (much-lt 1 ns) excitation of atoms and molecules. Extensive results have been reported for electron and photon emission from atoms subject to high-intensity lasers. This wealth of data has greatly increased our detailed knowledge of the effects of electromagnetic radiation on the electrons in these systems. The richness of these results has encouraged the development of new theoretical methods to provide an understanding of the observations. This paper reports that one of the major techniques being used to study the dynamics of excitation and ionization is the direct solution of the time-dependent Schrodinger equation for an atom or molecule in a pulse laser field. The time-dependent methods allow the exact calculation of above-threshold ionization (ATI) spectra for real (three-dimensional) hydrogenic systems and of photon emission from atoms excited by lasers. Recently the possibility of high-frequency, high-intensity suppression of ionization has also been addressed

  6. Pair configurations to molecular activity coefficients : PAC-MAC

    NARCIS (Netherlands)

    Sweere, A.J.M.

    2017-01-01

    This thesis provides an overview of the development of the Pair Configuration to Molecular Activity Coefficient (PAC-MAC) model. PAC-MAC is a computational method to predict thermodynamic miscibility properties of various molecular solutions. Examples of calculated thermodynamic miscibility

  7. Annotation and BAC/PAC localization of nonredundant ESTs from ...

    Indian Academy of Sciences (India)

    Unknown

    2002-04-25

    Apr 25, 2002 ... Putative functions were assigned at a stringency E value of 10–6 in. BLASTN and BLASTX algorithms. To understand the gene structure and function further, we have utilized the publicly available finished and unfinished rice BAC/PAC (BAC, bacterial artificial chromosome; PAC, P1 artificial chromosome) ...

  8. PC reporting system for radiologists: practical use under PACS environment.

    Science.gov (United States)

    Nakata, N; Yoshihiro, S; Miida, K; Tashima, M; Sunakawa, Y; Harada, J; Tada, S; Fukuda, K

    2001-07-01

    To evaluate the practical usefulness of several types of the reporting system especially for radiologists, we have developed and employed several reporting systems. We categorized those reporting systems as follows (1) stand alone PC reporting system; (2) linked reporting system with PACS environment; (3) integrated three-dimensional (3D) imaging workstation (WS) with the intranet. We have evaluated the advantages and disadvantages of those three systems, and compared between the reporting system without PACS and network reporting system with PACS. Using linked reporting system with PACS, radiologists could easily reference both previous reports and archived diagnostic images, and also make their teaching files quickly. In conclusion, the reporting system under PACS environment is found to be practical and helpful for Japanese radiologists.

  9. The Internet as a Medium of Training for Picture Archival and Communication Systems (PACS).

    Science.gov (United States)

    Majid, Shaheen; Misra, Ramesh Kumar

    2002-01-01

    Explores the potential of Web-based training for PACS (Picture Archival and Communication Systems) used in radiology departments for the storage and archiving of patients' medical images. Reports results of studies in three hospitals in Malaysia, Singapore and the Philippines that showed that the Internet can be used effectively for training.…

  10. La gaitana del Pacífico

    Directory of Open Access Journals (Sweden)

    Rogerio Velásquez

    1962-03-01

    Full Text Available La conquista del Pacífico colombiano presenta escenas en extremo vigorosas. La odisea de Andagoya al arribar a Birú o Biruquete en 1522, contada y cantada por él mismo en la relación de los sucesos de Pedrarias-Dávila; la marcha de pizarro y almagro por tierras donde llueve y relampaguea todos los días hasta dar con Atacames, después de cuatro años de heroicos y dificultosos momentos, son hechos dignos de enumerarse y destacarse como que dan la medida de un mundo de espejismo, de acantilados y de olas, de grutas y túneles, de vientos y pantanos en cuyo centro el hombre de las riberas es un juguete del clima, de las plagas y las necesidades.

  11. Workflow optimization beyond RIS and PACS

    International Nuclear Information System (INIS)

    Treitl, M.; Wirth, S.; Lucke, A.; Nissen-Meyer, S.; Trumm, C.; Rieger, J.; Pfeifer, K.-J.; Reiser, M.; Villain, S.

    2005-01-01

    Technological progress and the rising cost pressure on the healthcare system have led to a drastic change in the work environment of radiologists today. The pervasive demand for workflow optimization and increased efficiency of its activities raises the question of whether by employment of electronic systems, such as RIS and PACS, the potentials of digital technology are sufficiently used to fulfil this demand. This report describes the tasks and structures in radiology departments, which so far are only insufficiently supported by commercially available electronic systems but are nevertheless substantial. We developed and employed a web-based, integrated workplace system, which simplifies many daily tasks of departmental organization and administration apart from well-established tasks of documentation. Furthermore, we analyzed the effects exerted on departmental workflow by employment of this system for 3 years. (orig.) [de

  12. Effect of Poly Aluminium Chloride (PAC) on some blood constituents of Nile Tilapia (Oreochromis niloticus)

    International Nuclear Information System (INIS)

    Adam, H. M.; Agab, H.

    2006-01-01

    Poly aluminium chloride (PAC) is an urban drinking water purification substance that was introduced recently in Sudan and used to substitute polymer poly diallyl dimethyl aluminium chloride (DADMAC) and aluminium sulphate in water purification treatments. This study was conducted to determine its effects on fish health, which is is considered a biological indicator and an essential component of fresh water ecosystem. In this experiment, PAC was used in three different concentrations (0.1, 0.2 and 0.3 ml/1) in experimental tanks to achieve the desirable doses for the study. The tanks were populated by Nile Tilapia fingerlings (Oreochromis niloticus) with an average weight ranging between 70 and 100 grams. Exposure of this fish to PAC resulted in an immediate signification reduction (P<0.01) in haemoglobin concentration, erythrocytes count, packed cell volume, mean corpuscular volume and mean corpuscular haemoglobin concentration of experimental fingerlings blood. The degree of reduction in these parameters was directly proportional to the concentration of PAC used. (Author)

  13. Three-tiered integration of PACS and HIS toward next generation total hospital information system.

    Science.gov (United States)

    Kim, J H; Lee, D H; Choi, J W; Cho, H I; Kang, H S; Yeon, K M; Han, M C

    1998-01-01

    The Seoul National University Hospital (SNUH) started a project to innovate the hospital information facilities. This project includes installation of high speed hospital network, development of new HIS, OCS (order communication system), RIS and PACS. This project aims at the implementation of the first total hospital information system by seamlessly integrating these systems together. To achieve this goal, we took three-tiered systems integration approach: network level, database level, and workstation level integration. There are 3 loops of networks in SNUH: proprietary star network for host computer based HIS, Ethernet based hospital LAN for OCS and RIS, and ATM based network for PACS. They are linked together at the backbone level to allow high speed communication between these systems. We have developed special communication modules for each system that allow data interchange between different databases and computer platforms. We have also developed an integrated workstation in which both the OCS and PACS application programs run on a single computer in an integrated manner allowing the clinical users to access and display radiological images as well as textual clinical information within a single user environment. A study is in progress toward a total hospital information system in SNUH by seamlessly integrating the main hospital information resources such as HIS, OCS, and PACS. With the three-tiered systems integration approach, we could successfully integrate the systems from the network level to the user application level.

  14. Affective Dependence and Aggression: An Exploratory Study

    OpenAIRE

    Petruccelli, Filippo; Diotaiuti, Pierluigi; Verrastro, Valeria; Petruccelli, Irene; Federico, Roberta; Martinotti, Giovanni; Fossati, Andrea; Di Giannantonio, Massimo; Janiri, Luigi

    2014-01-01

    Introduction. Emotionally dependent subjects may engage in controlling, restrictive, and aggressive behaviours, which limit their partner’s autonomy. The underlying causes of such behaviours are not solely based on levels of aggression, but act as a mean of maintaining the subject’s own sense of self-worth, identity, and general functioning. Objective. The aim of the paper is to explore the correlation between affective dependency and reactive/proactive aggression and to evaluate individual d...

  15. Affective dependence and aggression: an exploratory study.

    Science.gov (United States)

    Petruccelli, Filippo; Diotaiuti, Pierluigi; Verrastro, Valeria; Petruccelli, Irene; Federico, Roberta; Martinotti, Giovanni; Fossati, Andrea; Di Giannantonio, Massimo; Janiri, Luigi

    2014-01-01

    Emotionally dependent subjects may engage in controlling, restrictive, and aggressive behaviours, which limit their partner's autonomy. The underlying causes of such behaviours are not solely based on levels of aggression, but act as a mean of maintaining the subject's own sense of self-worth, identity, and general functioning. The aim of the paper is to explore the correlation between affective dependency and reactive/proactive aggression and to evaluate individual differences as predisposing factors for aggressive behaviour and emotional dependency. The Spouse-Specific Dependency Scale (SSDS) and the Reactive Proactive Questionnaire (RPQ) were administered to a sample of 3375 subjects. In the whole sample, a positive correlation between emotional dependency and proactive aggression was identified. Differences with regard to sex, age group, and geographical distribution were evidenced for the scores of the different scales. A fundamental distinction between reactive and proactive aggression was observed, anchoring proactive aggression more strictly to emotional dependency. Sociocultural and demographical variables, together with the previous structuring of attachment styles, help to determine the scope, frequency, and intensity of the demands made to the partner, as well as to feed the fears of loss, abandonment, or betrayal.

  16. Affective Dependence and Aggression: An Exploratory Study

    Directory of Open Access Journals (Sweden)

    Filippo Petruccelli

    2014-01-01

    Full Text Available Introduction. Emotionally dependent subjects may engage in controlling, restrictive, and aggressive behaviours, which limit their partner’s autonomy. The underlying causes of such behaviours are not solely based on levels of aggression, but act as a mean of maintaining the subject’s own sense of self-worth, identity, and general functioning. Objective. The aim of the paper is to explore the correlation between affective dependency and reactive/proactive aggression and to evaluate individual differences as predisposing factors for aggressive behaviour and emotional dependency. Methods. The Spouse-Specific Dependency Scale (SSDS and the Reactive Proactive Questionnaire (RPQ were administered to a sample of 3375 subjects. Results. In the whole sample, a positive correlation between emotional dependency and proactive aggression was identified. Differences with regard to sex, age group, and geographical distribution were evidenced for the scores of the different scales. Conclusion. A fundamental distinction between reactive and proactive aggression was observed, anchoring proactive aggression more strictly to emotional dependency. Sociocultural and demographical variables, together with the previous structuring of attachment styles, help to determine the scope, frequency, and intensity of the demands made to the partner, as well as to feed the fears of loss, abandonment, or betrayal.

  17. Sex in the PAC: A hidden affair in dark septate endophytes?

    Directory of Open Access Journals (Sweden)

    Duò Angelo

    2011-09-01

    Full Text Available Abstract Background Fungi are asexually and sexually reproducing organisms that can combine the evolutionary advantages of the two reproductive modes. However, for many fungi the sexual cycle has never been observed in the field or in vitro and it remains unclear whether sexual reproduction is absent or cryptic. Nevertheless, there are indirect approaches to assess the occurrence of sex in a species, such as population studies, expression analysis of genes involved in mating processes and analysis of their selective constraints. The members of the Phialocephala fortinii s. l. - Acephala applanata species complex (PAC are ascomycetes and the predominant dark septate endophytes that colonize woody plant roots. Despite their abundance in many ecosystems of the northern hemisphere, no sexual state has been identified to date and little is known about their reproductive biology, and how it shaped their evolutionary history and contributes to their ecological role in forest ecosystems. We therefore aimed at assessing the importance of sexual reproduction by indirect approaches that included molecular analyses of the mating type (MAT genes involved in reproductive processes. Results The study included 19 PAC species and > 3, 000 strains that represented populations from different hosts, continents and ecosystems. Whereas A. applanata had a homothallic (self-fertile MAT locus structure, all other species were structurally heterothallic (self-sterile. Compatible mating types were observed to co-occur more frequently than expected by chance. Moreover, in > 80% of the populations a 1:1 mating type ratio and gametic equilibrium were found. MAT genes were shown to evolve under strong purifying selection. Conclusions The signature of sex was found in worldwide populations of PAC species and functionality of MAT genes is likely preserved by purifying selection. We hypothesize that cryptic sex regularely occurs in the PAC and that further field studies and in

  18. The Protective Role of PAC1-Receptor Agonist Maxadilan in BCCAO-Induced Retinal Degeneration.

    Science.gov (United States)

    Vaczy, A; Reglodi, D; Somoskeoy, T; Kovacs, K; Lokos, E; Szabo, E; Tamas, A; Atlasz, T

    2016-10-01

    A number of studies have proven that pituitary adenylate cyclase activating polypeptide (PACAP) is protective in neurodegenerative diseases. Permanent bilateral common carotid artery occlusion (BCCAO) causes severe degeneration in the rat retina. In our previous studies, protective effects were observed with PACAP1-38, PACAP1-27, and VIP but not with their related peptides, glucagon, or secretin in BCCAO. All three PACAP receptors (PAC1, VPAC1, VPAC2) appear in the retina. Molecular and immunohistochemical analysis demonstrated that the retinoprotective effects are most probably mainly mediated by the PAC1 receptor. The aim of the present study was to investigate the retinoprotective effects of a selective PAC1-receptor agonist maxadilan in BCCAO-induced retinopathy. Wistar rats were used in the experiment. After performing BCCAO, the right eye was treated with intravitreal maxadilan (0.1 or 1 μM), while the left eye was injected with vehicle. Sham-operated rats received the same treatment. Two weeks after the operation, retinas were processed for standard morphometric and molecular analysis. Intravitreal injection of 0.1 or 1 μM maxadilan caused significant protection in the thickness of most retinal layers and the number of cells in the GCL compared to the BCCAO-operated eyes. In addition, 1 μM maxadilan application was more effective than 0.1 μM maxadilan treatment in the ONL, INL, IPL, and the entire retina (OLM-ILM). Maxadilan treatment significantly decreased cytokine expression (CINC-1, IL-1α, and L-selectin) in ischemia. In summary, our histological and molecular analysis showed that maxadilan, a selective PAC1 receptor agonist, has a protective role in BCCAO-induced retinal degeneration, further supporting the role of PAC1 receptor conveying the retinoprotective effects of PACAP.

  19. Implementation and Validation of PACS Integrated Peer Review for Discrepancy Recording of Radiology Reporting.

    Science.gov (United States)

    Olthof, A W; van Ooijen, P M A

    2016-09-01

    The purpose of this work is to demonstrate the possibility of implementation of a PACS-integrated peer review system based on RADPEER™ classification providing a step-wise implementation plan utilizing features already present in the standard PACS implementation and without the requirement of additional software development. Furthermore, we show the usage and effects of the system during the first 30 months of usage. To allow fast and easy implementation into the daily workflow the key-word feature of the PACS was used. This feature allows to add a key-word to an imaging examination for easy searching in the PACS database (e.g. by entering keywords for different kinds of pathology). For peer review we implemented a keyword structure including a code for each of the existing RADPEER™ scoring language terms and a keyword with the phrase "second reading" followed by the name of the individual radiologist. The use of the short-keys to enter the codes in relation to the peer review was a simple to use solution. During the study 599 reports were peer reviewed. The active participation in this study of the radiologists varies and ranges from 3 to 327 reviews per radiologist. The number of peer review is highest in CT and CR. There are no significant technical obstacles to implement a PACS-integrated RADPEER™ -system based on key-words allowing easy integration of peer review into the daily routine without the requirement of additional software. Peer review implemented in a non-random setting based on relevant priors could already help in increasing the quality of radiological reporting and serve as continuing education among peers. Decisiveness, tact and trust are needed to promote use of the system and collaborative discussion of the results by radiologist.

  20. Expression of PACAP and PAC1 Receptor in Normal Human Thyroid Gland and in Thyroid Papillary Carcinoma.

    Science.gov (United States)

    Bardosi, Sebastian; Bardosi, Attila; Nagy, Zsuzsanna; Reglodi, Dora

    2016-10-01

    Pituitary adenylate cyclase activating polypeptide (PACAP) belongs to the vasoactive intestinal peptide-secretin-glucagon peptide family, isolated first from ovine hypothalamus. The diverse physiological effects of PACAP are known mainly from animal experiments, including several actions in endocrine glands. Alteration of PACAP expression has been shown in several tumors, but changes in expression of PACAP and its specific PAC1 receptor in human thyroid gland pathologies have not yet been investigated. Therefore, the aim of the present study was to investigate expression of PACAP and its PAC1 receptor in human thyroid papillary carcinoma, the most common endocrine malignant tumor. PACAP and PAC1 receptor expressions were investigated from thyroid gland samples of patients with papillary carcinomas. The staining intensity of follicular epithelial cells and thyroid colloid of tumor tissue was compared to that of tumor-free tissue in the same thyroid glands in a semi-quantitative way. Our results reveal that both PACAP(-like) and PAC1 receptor(-like) immunoreactivities are altered in papillary carcinoma. Stronger PACAP immunoreactivity was observed in active follicles. Colloidal PACAP immunostaining was either lacking or very weak, and more tumorous cells displayed strong apical immunoreactivity. Regarding PAC1 receptor, cells of the normal thyroid tissue showed strong granular expression, which was lacking in the tumor cells. The cytoplasm of tumor cells displayed weak, minimal staining, while in a few tumor cells we observed strong PAC1 receptor expression. This pattern was similar to that observed in the PACAP expression, but fewer in number. In summary, we showed alteration of PACAP and PAC1 receptor expression in human thyroid papillary carcinoma, indicating that PACAP regulation is disturbed in tumorous tissue of the thyroid gland. The exact role of PACAP in thyroid tumor growth should be further explored.

  1. PacIOOS Nearshore Sensor 08 (NS08): Koror, Palau

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The nearshore sensors are part of the Pacific Islands Ocean Observing System (PacIOOS) and are designed to measure a variety of ocean parameters at fixed point...

  2. MIRIAM: The PACS Project in Paris: Overview and Implementation

    OpenAIRE

    Primo, Henri; Picard, Jean Emmanuel

    1997-01-01

    In this article the authors describe the Management Informatique de la Radiologie et de l’Imagerie Médicale (MIRIAM) major picture archiving and communication system (PACS) project in Paris, France. The Assistance Publique of Paris, France is a healthcare provider and took the initiative to start the largest PACS program in Europe to date. The MIRIAM project will start in 1997 and will be used in different, consecutive phases. A consortium of several companies is in charge of the implementati...

  3. On stochastic approximation algorithms for classes of PAC learning problems

    Energy Technology Data Exchange (ETDEWEB)

    Rao, N.S.V.; Uppuluri, V.R.R.; Oblow, E.M.

    1994-03-01

    The classical stochastic approximation methods are shown to yield algorithms to solve several formulations of the PAC learning problem defined on the domain [o,1]{sup d}. Under some assumptions on different ability of the probability measure functions, simple algorithms to solve some PAC learning problems are proposed based on networks of non-polynomial units (e.g. artificial neural networks). Conditions on the sizes of these samples required to ensure the error bounds are derived using martingale inequalities.

  4. On stochastic approximation algorithms for classes of PAC learning problems.

    Science.gov (United States)

    Rao, N V; Uppuluri, V R; Oblow, E M

    1997-01-01

    The classical stochastic approximation methods are shown to yield algorithms to solve several formulations of the PAC learning problem defined on the domain [0,1](d). Under some smoothness conditions on the probability measure functions, simple algorithms to solve some PAC learning problems are proposed based on networks of nonpolynomial units (e.g. artificial neural networks). Conditions on the sizes of the samples required to ensure the error bounds are derived using martingale inequalities.

  5. PACS war room for global teleradiology

    Science.gov (United States)

    Chen, Doris T.; Ho, Bruce K. T.; Chao, Woodrew; Taira, Ricky K.; Kangarloo, Hooshang

    1995-05-01

    UCLA is beginning teleradiology projects in Latin America, Asian Pacific, and the U.S. The UCLA teleradiology system communicates with remote imaging centers through a T1 based WAN and satellite technology. A network management center, i.e., PACS war room, with graphical user interface allows the system manager to monitor and control different elements of the system through various levels of abstraction from one location. The network manager software can monitor the activities of both hardware and software devices in the remote imaging centers, LAN and WAN performance, telearchiving and teleaccess pattern. Telearchiving can be monitored by graphically indicating large image movements between jukeboxes and over LAN or WAN. Once the teleradiology system is configured, the image flow pattern in a teleradiology center is predictable. Manual intervention of these teleradiology system functions is easily done through menu control in the war room display. A centralized network management with the global view of a teleradiology system has been developed. It can give commands to the elements of the system to tune the system for efficient utilization of the system resources. These managerial functions scale with the teleradiology system which is expandable to include many more potential remote imaging centers.

  6. [Validation of the Physical Appearance Comparison Scale (PACS) in a German Sample: Psychometric Properties and Association with Eating Behavior, Body Image and Self-Esteem].

    Science.gov (United States)

    Claire Mölbert, Simone; Hautzinger, Martin; Karnath, Hans-Otto; Zipfel, Stephan; Giel, Katrin

    2017-02-01

    The Physical Appearance Comparison Scale (PACS [14]) is the most commonly used validated measure of body-related social comparison habits. Here we investigate reliability and construct validity of the PACS in a German sample. Participants (n=75 men, n=75 women and n=25 women with a confirmed diagnosis of anorexia nervosa) completed the PACS along with measures of eating disorder pathology, body image and self-esteem. Results show an adequate internal consistency of the PACS for the female subgroups and medium to high correlations with eating disorder pathology, body image and self-esteem. PACS total score differed significantly between groups, with men scoring lowest and women with anorexia nervosa scoring highest. We conclude that the PACS is a sufficiently reliable and valid measure of body-related social comparison habits in women. In men, it should only be used with special care. The PACS is generally suitable to promote patient studies testing the role of social comparisons for the patho-mechanisms of eating disorders. © Georg Thieme Verlag KG Stuttgart · New York.

  7. Concentration dependence of inhomogeneous broadening in perturbed angular correlation spectroscopy

    Science.gov (United States)

    Moreno, Carlos; Hodges, Jeffery A.; Park, Tyler; Stufflebeam, Michael; Evenson, W.; Matheson, P.; Zacate, M. O.

    2008-10-01

    Since real crystals always include defects, the effect of the defects on crystal properties depends on how many defects are present, i.e. on defect concentration. In perturbed angular correlation (PAC), these defects produce damping of the correlation signal in time and broadening of the frequency spectrum. This ``inhomogeneous broadening'' depends quantitatively on defect concentration, so the size of the broadening in a PAC spectrum can be a measure of the concentration of defects. Using simulated PAC spectra and independent component analysis to obtain the probability distribution function for electric field gradient (EFG) components, we have found defect concentration-dependent parameters for the probability functions. This allows us to calculate broadened PAC spectra for any selected defect concentration. It also allows us to fit defect concentration from an experimental PAC spectrum. This work will be applied initially to broadened PAC data from β-Mn, Al-doped β-Mn, and Sr2RuO4.

  8. Management system for a PACS network in a hospital environment

    Science.gov (United States)

    Mattheus, Rudy A.; Temmerman, Yvan; Verhelle, Filip; Osteaux, Michel

    1991-07-01

    The size of a typical data transfer in a PACS environment is several orders of magnitude larger than a typical data transfer in a local area computer network. PACS is also moving to a multi-vendor environment. To ensure reasonable response times to users, it is necessary to manage the image traffic on the PACS network explicitly, and for the heterogeneous network environment, tools for monitoring and maintenance are necessary. Modular network architectures, capable of reacting to growth and changes in traffic patterns, are essential. Knowledge about patient-radiologist and image flow which is available in the hospital environment can be exploited for careful planning and scheduling of network traffic. The authors designed and implemented a prototype network management system that makes the domain knowledge and the traffic management strategy explicit. In general, the term network management covers a wide range of tasks. Network design and configuration, for example, are network management tasks situated in the pre-operational phase. Network monitoring and control, including error detection, fault diagnosis, dynamic routing, etc., are network management tasks with a real-time aspect. This PACS is hierarchically organized. Each sub- department has its own local PACS. The paper focuses on the results of the implementation of the PACS architecture and, more precisely, on the network management aspects.

  9. Evolutionistic or revolutionary paths? A PACS maturity model for strategic situational planning.

    OpenAIRE

    Wetering, R. van de; Batenburg, R.; Lederman, R.

    2010-01-01

    PURPOSE: While many hospitals are re-evaluating their current Picture Archiving and Communication System (PACS), few have a mature strategy for PACS deployment. Furthermore, strategies for implementation, strategic and situational planning methods for the evolution of PACS maturity are scarce in the scientific literature. Consequently, in this paper we propose a strategic planning method for PACS deployment. This method builds upon a PACS maturity model (PMM), based on the elaboration of the ...

  10. Evaluation of the Users’ Continuous Intention to Use PACS Based on the Expectation Confirmation Model in Teaching Hospitals of Shiraz University of Medical Sciences

    Directory of Open Access Journals (Sweden)

    Mohtaram Nematolahi

    2017-01-01

    Full Text Available Introduction: Users’ behavioral intention to use the Picture Archiving and Communication System (PACS is important in the systems’ success and is an indicator of the users’ satisfaction with commitment and dependence on information systems. The present study aimed to evaluate the users’ continuous intention to use PACS based on the expectation confirmation model in educational hospitals of Shiraz University of Medical Sciences. Method: This cross-sectional study was conducted in Nemazee and Shahid Faghihi hospitals, Shiraz, Iran in 2014. The subjects were 50 general practitioners, residents and specialists selected through stratified random sampling. The study data were collected using a researcher-made questionnaire. The content validity of the questionnaire items was confirmed by five experts in health information management. To evaluate the accuracy of relationships among the measurement models, reliability criteria, including Cronbach’s alpha and composite reliability, convergent and divergent validity were used which showed acceptable reliability and validity. The data were entered into Smart PLS software, version 3.1.9 and analyzed through Structural Equation Modeling (SEM by using Partial Least Squares (PLS approach. Results: The results showed appropriate fitness of reliability indices (Cronbach’s alpha >0.7, composite reliability >0.7, loading >0.7, validity indices (AVE >0.5, structural model (redundancy =0.395, Q2CI=0.364, f2H5=0.524, R2CI=0.687, and the total model (GoF=0.518. Moreover, all the research hypotheses, except H1 (the relationship between expectation confirmation and perceived usefulness with T-value of 1.96. Conclusion: Expectation confirmation, perceived usefulness, and satisfaction were effective in continuous intention to use PACS. Thus, these factors should be considered by designers, developers, and managers while designing and implementing information systems to guarantee their success and improve the

  11. HyPac french platform on the hydrogen and fuel cells; HyPac plateforme francaise sur l'hydrogene et les piles a combustible

    Energy Technology Data Exchange (ETDEWEB)

    Lucchese, P. [N ' ERGY, 85 - Antigny (France)

    2008-07-01

    HyPac is a french platform on the hydrogen and fuel cells applications, created in 2008. the authors presents the opportunities of the french platform HyPac, the objectives, the participants and the budget. (A.L.B.)

  12. What Types Of Standards Would Be Useful In PACS Activities?

    Science.gov (United States)

    Baxter, Brent; Zeleznik, Michael; Macguire, Gerald

    1983-05-01

    Digital storage and retrival of diagnostic image information in a large medical center is dependent upon the interconnection and successful use of many types of electronic equipment. Much of this equipment may be sufficiently dissimilar to cause major interconnection problems. For these individual systems to function together in a picture archiving and communication system (PACS) network it is essential that of their use and operation be coordinated in a systematic manner according to standardized procedures. There are several benefits to the adoption and use of such standards: a) New equipment and software can be designed for parts of the system without the entire system becomming obsolete. b) Permanence of the archived image material will be unaffected by replacement of archive equipment. c) Communication of image data between medical centers will be simpler. This talk will outline desirable characteristics for standards designed to help meet these objectives. Aspects of archive system operation that are suitable for standardization will be discussed and contrasted with those most likely best left unspecified to encourage creative diversity.

  13. The role of metallic impurities in oxide semiconductors: first-principles calculations and PAC experiments

    Energy Technology Data Exchange (ETDEWEB)

    Errico, L.A.; Fabricius, G.; Renteria, M. [Departamento de Fisica, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, CC 67, 1900 La Plata (Argentina)

    2004-08-01

    We report an ab-initio comparative study of the electric-field-gradient tensor (EFG) and structural relaxations introduced by acceptor (Cd) and donor (Ta) impurities when they replace cations in a series of binary oxides: TiO{sub 2}, SnO{sub 2}, and In{sub 2}O{sub 3}. Calculations were performed with the Full-Potential Linearized-Augmented Plane Waves method that allows us to treat the electronic structure and the atomic relaxations in a fully self-consistent way. We considered different charge states for each impurity and studied the dependence on these charge states of the electronic properties and the structural relaxations. Our results are compared with available data coming from PAC experiments and previous calculations, allowing us to obtain a new insight on the role that metal impurities play in oxide semiconductors. It is clear from our results that simple models can not describe the measured EFGs at impurities in oxides even approximately. (copyright 2004 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  14. Shareware program for nuclear medicine and PET/CT PACS display and processing.

    Science.gov (United States)

    Barbaras, Larry; Tal, Ilan; Palmer, Matthew R; Parker, J Anthony; Kolodny, Gerald M

    2007-06-01

    Many of the functions necessary for imaging and analyzing nuclear medicine studies are not available on radiology PACS. Over the past 20 years, we have developed a user-friendly, easily installed software package for nuclear medicine study analysis, display, Web access, and database storage and an integrated display for fused PET/CT. We are making this software available as free shareware that can be used without a license on any PC. The software package was developed as a cooperative effort between house and attending staff and our nuclear medicine programmer. Particular emphasis was put on making functions intuitive and user friendly. A shareware nuclear medicine PACS software package including a display for fused PET/CT studies has been developed, extensively clinically tested, and is freely available on the Internet.

  15. PENURUNAN TOKSISITAS LEACHATE (AIR LINDI DARI TPAS PUTRI CEMPO MOJOSONGO SURAKARTA DENGAN PAC (POLY ALUMINUM CHLORIDE (Toxicity Reduction of Leachate from Putri Cempo Municipal Landfill (TPAS Mojosongo Surakarta with PAC (Poly Aluminium Chloride

    Directory of Open Access Journals (Sweden)

    Dwi Astuti

    2010-03-01

    Full Text Available ABSTRAK Tujuan penelitian ini adalah menetapkan persen penurunan toksisitas sesudah diperlakukan dengan PAC. Rancangan penelitian ini adalah eksperimen murni dengan pretest-posttest with control group design. Populasi dalam penelitian ini adalah air lindi yang berasal dari TPAS Putri Cempo MPAC: 25,06% (24 jam; 21,07% (48 jam; 17,49% (72 jam; dan 14,97% (96 jam. (2 Dengan perlakuan PAC: 89,44% (24 jam; 63,73% (48 jam; 49,99% (72 jam; dan 40,96% (96 jam. Sehingga persentase penurunan toksisitasnya adalah: 64,38% (24 jam, 42,66% (48 jam, 32,50% (72 jam, dan 25,99% (96 jam.    ABSTRACT The aims of the current study were to determine percentage of leachate toxicity reduction after treatment with PAC. The experimental design used was true experimental study with pretest-posttest with control group design. Population in this study was leachate from Putri Cempo Landfill (TPAS Putri Cempo Mojosongo Surakarta. The sample was 250 litres leachate obtained from the landfill outlet by quota sampling method. The results revealed the leachate toxicity based on LC50 24-96 hours were: (1 without PAC treatment: 25.06% (24 hours, 21.07% (48 hours, 17.49% (72 hours, and 14.97% (96 hours; (2 with PAC treatment: 89.44% (24 hours, 63.73% (48 hours, 49.99% (72 hours, and 40.96% (96 hours. Therefore, the toxicity reductions were: 64.38% (24 hours, 42.66% (48 hours, 32.50% (72 hours, and 25.99% (96 hours.

  16. DICOM data migration for PACS transition: procedure and pitfalls.

    Science.gov (United States)

    van Ooijen, Peter M A; Aryanto, Kadek Yota; Broekema, André; Horii, Steven

    2015-07-01

    Transition from one Picture Archiving and Communication System (PACS) to the other is costly and disruptive. Especially the migration of the DICOM data from the legacy to the new PACS is a very challenging task, and although such a migration will happen in every hospital, literature on methodologies to follow and possible problems and pitfalls is scarce. The objective of this work is to provide insight in the prerequisites for the legacy PACS before starting the migration with respect to vendor and DICOM considerations. The steps involved in migration, possible methodologies, and areas of specific interest when planning migration are given. Possible challenges and problems are defined as well as issues that are often overlooked. A step-wise approach should be implemented for data migration. Careful planning and testing, continuous observation of the process, and involvement of all stakeholders including the old and new vendors are crucial for a successful transition from one PACS to the other. A proper test migration is a crucial step in the PACS transition process, which can eliminate many of the problems in the actual migration. However, with any migration, there has to be a willingness to take a limited amount of risk since not all problems can nor will be identified in the test migration.

  17. Relating PAC damping to EFG fluctuation rates through the PAC relaxation peak

    Energy Technology Data Exchange (ETDEWEB)

    Park, Tyler [Utah Valley University, Department of Physics (United States); Hodges, Jeffery A. [University of Utah, Department of Physics (United States); Moreno, Carlos; Stufflebeam, Michael; Evenson, William E., E-mail: bill@evenson.ch; Matheson, P. [Utah Valley University, Department of Physics (United States); Zacate, M. O. [Northern Kentucky University, Department of Physics and Geology (United States); Collins, Gary S. [Washington State University, Department of Physics and Astronomy (United States)

    2011-07-15

    A perturbed angular correlation (PAC) experiment that measures dynamic damping also needs information about the fundamental quadrupole frequency to relate the damping as a function of temperature to the EFG fluctuation rate. When the experiment is unable to access slow electric field gradient (EFG) fluctuations that show the fundamental quadrupole frequency directly, one needs additional information to determine the hyperfine field parameters and thereby the connection between observed damping and EFG fluctuation rates. One way to solve this problem is to estimate the hyperfine parameters from the fluctuation rate for maximum damping (i.e. at the relaxation peak) or from the rate of maximum damping. This work relates both the maximum damping rate and the fluctuation rate at the relaxation peak to EFG magnitudes (or quadrupole frequencies) for five dynamic N-state symmetric models of fluctuating EFGs.

  18. Relating PAC damping to EFG fluctuation rates through the PAC relaxation peak

    International Nuclear Information System (INIS)

    Park, Tyler; Hodges, Jeffery A.; Moreno, Carlos; Stufflebeam, Michael; Evenson, William E.; Matheson, P.; Zacate, M. O.; Collins, Gary S.

    2011-01-01

    A perturbed angular correlation (PAC) experiment that measures dynamic damping also needs information about the fundamental quadrupole frequency to relate the damping as a function of temperature to the EFG fluctuation rate. When the experiment is unable to access slow electric field gradient (EFG) fluctuations that show the fundamental quadrupole frequency directly, one needs additional information to determine the hyperfine field parameters and thereby the connection between observed damping and EFG fluctuation rates. One way to solve this problem is to estimate the hyperfine parameters from the fluctuation rate for maximum damping (i.e. at the relaxation peak) or from the rate of maximum damping. This work relates both the maximum damping rate and the fluctuation rate at the relaxation peak to EFG magnitudes (or quadrupole frequencies) for five dynamic N-state symmetric models of fluctuating EFGs.

  19. Simulated models of perturbed angular correlation (PAC) spectroscopy in a 4-state+S system

    Science.gov (United States)

    Hodges, Jeffery A.; Stufflebeam, Michael A.; Evenson, William E.; Matheson, P.; Zacate, M. O.

    2007-10-01

    Cerium oxide has a cubic crystal structure. A vacancy in CeO2 can be trapped by a probe atom and hop among equivalent 1st or 2nd neighbor sites of the probe, producing a fluctuating electric field gradient (EFG) at the probe nucleus. We have simulated the perturbed angular correlation (PAC) spectrum due to such a changing EFG (4-state model), as well as the case with an additional static background EFG (4-state+S). We have studied the effect of changing the defect hopping rates on the resulting spectrum and the inferred hyperfine parameters. We have analyzed these data to determine experimental conditions under which nonequilibrium initial probe distributions can be detected by PAC.

  20. Budget variance analysis of a departmentwide implementation of a PACS at a major academic medical center.

    Science.gov (United States)

    Reddy, Arra Suresh; Loh, Shaun; Kane, Robert A

    2006-01-01

    In this study, the costs and cost savings associated with departmentwide implementation of a picture archiving and communication system (PACS) as compared to the projected budget at the time of inception were evaluated. An average of $214,460 was saved each year with a total savings of $1,072,300 from 1999 to 2003, which is significantly less than the $2,943,750 projected savings. This discrepancy can be attributed to four different factors: (1) overexpenditures, (2) insufficient cost savings, (3) unanticipated costs, and (4) project management issues. Although the implementation of PACS leads to cost savings, actual savings will be much lower than expected unless extraordinary care is taken when devising the budget.

  1. Altered circadian food anticipatory activity rhythms in PACAP receptor 1 (PAC1) deficient mice

    DEFF Research Database (Denmark)

    Hannibal, Jens; Georg, Birgitte; Fahrenkrug, Jan

    2016-01-01

    glutamate receptors and the specific PACAP type 1 (PAC1) receptor. Light entrainment occurs during the twilight zones and has little effect on clock phase during daytime. When nocturnal animals have access to food only for a few hours during the resting phase at daytime, they adapt behavior...... in RF with access to food for 4-5 h during the subjective day, a significant change in behavior was observed in PAC1-/- mice compared to PAC1+/+ mice. While PAC1-/- mice showed similar FAA as PAC1+/+ animals in FPP at 300 lux, PAC1-/- mice demonstrated an advanced onset of FAA with a nearly 3-fold...

  2. PacBio But Not Illumina Technology Can Achieve Fast, Accurate and Complete Closure of the High GC, Complex Burkholderia pseudomallei Two-Chromosome Genome

    Directory of Open Access Journals (Sweden)

    Jade L. L. Teng

    2017-08-01

    Full Text Available Although PacBio third-generation sequencers have improved the read lengths of genome sequencing which facilitates the assembly of complete genomes, no study has reported success in using PacBio data alone to completely sequence a two-chromosome bacterial genome from a single library in a single run. Previous studies using earlier versions of sequencing chemistries have at most been able to finish bacterial genomes containing only one chromosome with de novo assembly. In this study, we compared the robustness of PacBio RS II, using one SMRT cell and the latest P6-C4 chemistry, with Illumina HiSeq 1500 in sequencing the genome of Burkholderia pseudomallei, a bacterium which contains two large circular chromosomes, very high G+C content of 68–69%, highly repetitive regions and substantial genomic diversity, and represents one of the largest and most complex bacterial genomes sequenced, using a reference genome generated by hybrid assembly using PacBio and Illumina datasets with subsequent manual validation. Results showed that PacBio data with de novo assembly, but not Illumina, was able to completely sequence the B. pseudomallei genome without any gaps or mis-assemblies. The two large contigs of the PacBio assembly aligned unambiguously to the reference genome, sharing >99.9% nucleotide identities. Conversely, Illumina data assembled using three different assemblers resulted in fragmented assemblies (201–366 contigs, sharing only 92.2–100% and 92.0–100% nucleotide identities to chromosomes I and II reference sequences, respectively, with no indication that the B. pseudomallei genome consisted of two chromosomes with four copies of ribosomal operons. Among all assemblies, the PacBio assembly recovered the highest number of core and virulence proteins, and housekeeping genes based on whole-genome multilocus sequence typing (wgMLST. Most notably, assembly solely based on PacBio outperformed even hybrid assembly using both PacBio and Illumina

  3. Potential time savings to radiology department personnel in a PACS-based environment

    Science.gov (United States)

    Saarinen, Allan O.; Wilson, M. C.; Iverson, Scott C.; Loop, John W.

    1990-08-01

    A purported benefit of digital imaging and archiving of radiographic procedures is the presumption of time savings to radiologists, radiology technologists, and radiology departmentpersonnel involved with processingfilms and managing theflimfile room. As part of the University of Washington's evaluation of Picture Archiving and Communication Systems (PACS)for the U.S. Army Medical Research and Development Command, a study was performed which evaluated the current operationalpractices of the film-based radiology department at the University of Washington Medical Center (UWMC). Industrial engineering time and motion studies were conducted to document the length of time requiredforfilm processing in various modalities, the proportion of the total exam time usedforfilm processing, the amount of time radiologists spent searchingfor and looking at images, and the amount of time file room personnel spent collating reports, making loans, updatingfilm jacket information, and purging files. This evaluation showed that better than one-half of the tasks in the file room may be eliminated with PACS and radiologists may save easily 10 percent of the time they spend reading films by no longer having to searchforfilms. Radiology technologists may also save as much as 10 percent of their time with PACS, although this estimate is subject to significant patient mix aberrations and measurement error. Given that the UWMC radiology department operates efficiently, similar improvements are forecast for other radiology departments and larger improvements areforecastfor less efficient departments.

  4. Changes of workflow in a radiolocigal department with RIS, PACS and flatpanel detectors implementation

    International Nuclear Information System (INIS)

    Imhof, H.; Dirisamer, A.; Fischer, H.; Grampp, S.; Heiner, L.; Kaderk, M.; Krestan, C.; Kainberger, F.

    2002-01-01

    Implementation of radiological information systems (RIS) and picture archiving and communicating systems (PACS) results in significant changes of workflow in a radiological department. Additional connection with flatpanel detectors leads to a shortening of the work process. RIS and PACS implementation alone reduces the complete workflow by 21-80%. With flatpanel technology the image production process is further shortened by 25-30%. The workflow-steps are changed from original 17-12 with the implementation of RIS and PACS and to 5 with the integrated use of flatpanels.This clearly recognizable advantages in the workflow need an according financial investment. Several studies could show that the capitalisationfactor calculated over eight years is positive, with a gain range between 5-25%. Whether the additional implementation of flatpanel detectors results also in a positive capitalisation over the years, cannot be estimated exactly, at the moment, because the experiences are too short. Particuarly critical are the interfaces, which needs a constant quality control. Our flatpanel detector-system is fixed, special images - as we have them in about 3-5% of all cases - need still conventional filmscreen or phosphorplate-systems. Full-spine and long-leg examinations cannot be performed with sufficient exactness. Without any questions implementation of integrated RIS, PACS and flatpanel detector-system needs excellent training of the employees, because of the changes in workflow etc. The main profits of such an integrated implementation are an increase in quality in image and report datas, easier handling - there are almost no more cassettes necessary - and excessive shortening of workflow. (orig.) [de

  5. PAC++: Object-oriented platform for accelerator codes

    International Nuclear Information System (INIS)

    Malitsky, N.; Reshetov, A.; Bourianoff, G.

    1994-06-01

    Software packages in accelerator physics have relatively long life cycles. They had been developed and used for a wide range of accelerators in the past as well as for the current projects. For example, the basic algorithms written in the first accelerator Program TRANSPORT are actual for design of most magnet systems. Most of these packages had been implemented on Fortran. But this language is rather inconvenient as a basic language for large integrated projects that possibly could include real-time data acquisition, data base access, graphic riser interface modules (GUI), arid other features. Some later accelerator programs had been based on object-oriented tools (primarily, C++ language). These range from systems for advanced theoretical studies to control system software. For the new generations of accelerators it would be desirable to have an integrated platform in which all simulation and control tasks will be considered with one point of view. In this report the basic principles of an object-oriented platform for accelerator research software (PAC++) are suggested and analyzed. Primary objectives of this work are to enable efficient self-explaining realization of the accelerator concepts and to provide an integrated environment for the updating and the developing of the code

  6. Image acquisition for the pediatric radiology PACS module

    International Nuclear Information System (INIS)

    Ho, B.K.; Morioka, C.; Mankovich, N.J.; Stewart, B.; Huang, H.K.

    1987-01-01

    The prototype PACS module implemented at UCLA's pediatric radiology section has multi-modality access to image data from any of the three types of sources: digital modalities (i.e. CT, MR, and DSA), the Fuji Computed Radiography unit (FCR), and laser film digitizers. An interface unit was built to facilitate real-time data transfer from the FCR to the VAX11/750 which serves as the PACS host computer. The design of the interface unit, methods for linking to digital modalities, and characteristics of two film digitizers are described

  7. PAC - Perturbed Angular Correlation spectrometer with six BaF2 detectors

    International Nuclear Information System (INIS)

    Domienikan, Claudio; Lapolli, Andre L.; Carbonari, Artur W.; Saxena, Rajendra N.; Schoueri, Roberto M.

    2009-01-01

    A Perturbed Angular Correlation (PAC) spectrometer with six conical BaF 2 detectors was built. The increased number of detectors in relation with the current configuration of the spectrometer (with four detectors), extends the number of delayed γ- γ coincidence spectra from 12 to 30 obtained simultaneously, reducing the time of PAC measurements. The standard multichannel analyzer (MCA) commonly used in these types of spectrometers was replaced with an ultra fast analog to digital converter (8715 ADC - CANBERRA R ) and a high speed digital input-output (I/O) board (6534 Acquisition system - NATIONAL INSTRUMENTS R ). The experimental data consisting of relevant information about the delayed γ-γ coincidence events generated from different combinations of detectors (for example: the timing information, start and stop detector identification, coincidence validation etc.) are stored in a file-mode in the hard disk of a computer. This information can be processed at a later stage by background data processing to generate and periodically refresh individual PAC spectra without interruption of the data collection process. The coincidence spectra are generated in real time by using LabVIEW software. The increased number of simultaneous spectra generated in this spectrometer improves the hyperfine parameters deduced from the TDPAC measurements. More important, the new spectrometer would be used for application of some interesting radioactive nuclei that can be used as probes in several hyperfine interaction studies. (author)

  8. PACS and teleradiology for on-call support of abdominal imaging

    Science.gov (United States)

    Horii, Steven C.; Garra, Brian S.; Mun, Seong K.; Zeman, Robert K.; Levine, Betty A.; Fielding, Robert

    1991-07-01

    One aspect of the Georgetown image management and communications system (IMACS or PACS) is a built-in capability to support teleradiology. Unlike many dedicated teleradiology systems, the support of this capability as a part of PACS means that any acquired images are remotely accessible, not just those specifically input for transmission. Over the past one and one-half years, two radiologists (SCH, BSG) in the abdominal imaging division of the department of radiology have been accumulating experience with teleradiology for on-call support of emergency abdominal imaging, chiefly in ultrasound. As of the time of this writing, use of the system during on-call (one of these attending radiologists primarily responsible) or back-up call (the attending responsible for the Fellow on primary call) has resulted in a marked reduction in the number of times one of them has to drive to the hospital at night or over the weekend. Approximately 80% of the time, use of the teleradiology system obviates having to go in to review a case. The remainder of the time, the radiologist has to perform a procedure (e.g., abscess drainage) or a scan (e.g., complex Doppler study) himself. This paper reviews the system used for teleradiology, how it is electronically and operationally integrated with the PACS, the clinical benefits and disadvantages of this use, and radiologist and referring physician acceptance.

  9. Modified EFG Components and Their Joint pdf for Use in Modeling ihb in PAC

    Science.gov (United States)

    Adams, M.; Matheson, P.; Park, T.; Stufflebeam, M.; Hodges, J.; Evenson, W. E.; Zacate, M. O.

    2012-10-01

    Spectra of hyperfine interactions involving the electric field gradient tensor (EFG) are subject to broadening by statistical variations of EFG components. In perturbed angular correlation (PAC) experiments, the inhomogeneous broadening (ihb) of the G2(c,t) spectrum is produced by randomly distributed lattice defects of concentration, c. The EFG tensor has two independent components. The concentration dependence of ihb is determined by the joint probability distribution function (pdf) of these components. In typical PAC analyses, the independent coordinates are assumed to be Vzz and the asymmetry parameter η= (2Vxx+Vzz)/Vzz. However, the pdf P(c,Vzz,η) is not known, and in any case it is easy to show that Vzz and η are highly correlated, and not independent. We have found that the application of the Czjzek transformation [1], followed by a simple conformal mapping produces two, nearly independent EFG coordinates W1(c,Vzz,η) and W2(c,Vzz,η). The pdfs of each coordinate are readily characterized, and their product P(c,W1,W2)=P1(c,W1)P2(c,W2) forms an appropriate joint pdf that can be used to model ihb in a variety of situations. We show the application of this method by reporting results modeling the concentration dependence of ihb in various PAC models, for simple cubic (sc), face-centered cubic (fcc) and body-centered cubic (bcc) lattices. [4pt] [1] Czjzek, G. Hyperfine Interactions 14(1983) 189-194.

  10. Pattern mining of user interaction logs for a post-deployment usability evaluation of a radiology PACS client

    NARCIS (Netherlands)

    Jorritsma, Wiard; Cnossen, Fokie; Dierckx, Rudi A.; Oudkerk, Matthijs; van Ooijen, Peter M. A.

    Objectives: To perform a post-deployment usability evaluation of a radiology Picture Archiving and Communication System (PACS) client based on pattern mining of user interaction log data, and to assess the usefulness of this approach compared to a field study. Methods: All user actions performed on

  11. Context indexing of digital cardiac ultrasound records in PACS

    Science.gov (United States)

    Lobodzinski, S. Suave; Meszaros, Georg N.

    1998-07-01

    Recent wide adoption of the DICOM 3.0 standard by ultrasound equipment vendors created a need for practical clinical implementations of cardiac imaging study visualization, management and archiving, DICOM 3.0 defines only a logical and physical format for exchanging image data (still images, video, patient and study demographics). All DICOM compliant imaging studies must presently be archived on a 650 Mb recordable compact disk. This is a severe limitation for ultrasound applications where studies of 3 to 10 minutes long are a common practice. In addition, DICOM digital echocardiography objects require physiological signal indexing, content segmentation and characterization. Since DICOM 3.0 is an interchange standard only, it does not define how to database composite video objects. The goal of this research was therefore to address the issues of efficient storage, retrieval and management of DICOM compliant cardiac video studies in a distributed PACS environment. Our Web based implementation has the advantage of accommodating both DICOM defined entity-relation modules (equipment data, patient data, video format, etc.) in standard relational database tables and digital indexed video with its attributes in an object relational database. Object relational data model facilitates content indexing of full motion cardiac imaging studies through bi-directional hyperlink generation that tie searchable video attributes and related objects to individual video frames in the temporal domain. Benefits realized from use of bi-directionally hyperlinked data models in an object relational database include: (1) real time video indexing during image acquisition, (2) random access and frame accurate instant playback of previously recorded full motion imaging data, and (3) time savings from faster and more accurate access to data through multiple navigation mechanisms such as multidimensional queries on an index, queries on a hyperlink attribute, free search and browsing.

  12. Operator interface design considerations for a PACS information management system

    Science.gov (United States)

    Steinke, James E.; Nabijee, Kamal H.; Freeman, Rick H.; Prior, Fred W.

    1990-08-01

    As prototype PACS grow into fully digital departmental and hospital-wide systems, effective information storage and retrieval mechanisms become increasingly important. Thus far, designers of PACS workstations have concentrated on image communication and display functionality. The new challenge is to provide appropriate operator interface environments to facilitate information retrieval. The "Marburg Model" 1 provides a detailed analysis of the functions, control flows and data structures used in Radiology. It identifies a set of "actors" who perform information manipulation functions. Drawing on this model and its associated methodology it is possible to identify four modes of use of information systems in Radiology: Clinical Routine, Research, Consultation, and Administration. Each mode has its own specific access requirements and views of information. An operator interface strategy appropriate for each mode will be proposed. Clinical Routine mode is the principal concern of PACS primary diagnosis workstations. In a full PACS implementation, such workstations must provide a simple and consistent navigational aid for the on-line image database, a local work list of cases to be reviewed, and easy access to information from other hospital information systems. A hierarchical method of information access is preferred because it provides the ability to start at high-level entities and iteratively narrow the scope of information from which to select subsequent operations. An implementation using hierarchical, nested software windows which fulfills such requirements shall be examined.

  13. Reasons for Picture Archiving and Communication System (PACS ...

    African Journals Online (AJOL)

    Background: The Picture Archiving and Communication System (PACS) has led to an increase in breached health records and violation of patient confidentiality. The South African constitution makes provision for human dignity and privacy, virtues which confidentiality seeks to preserve. Confidentiality thus constitutes a ...

  14. V-MAX: tempered optimism for better PAC reinforcement learning

    NARCIS (Netherlands)

    Rao, K.; Whiteson, S.

    2012-01-01

    Recent advances in reinforcement learning have yielded several PAC-MDP algorithms that, using the principle of optimism in the face of uncertainty, are guaranteed to act near-optimally with high probability on all but a polynomial number of samples. Unfortunately, many of these algorithms, such as

  15. Operator interface design for a PACS primary diagnosis workstation

    Science.gov (United States)

    Freeman, Rick H.; Neubecker, Cynthia S.; Keller, Scott A.; Steinke, James E.

    1990-08-01

    One of the challenges to the PACS workstation designer is to cost effectively fulfill the range of requirements from those of the entry-level system to those of the fully digital hospital. The workstation must therefore support many of the functions of film-based image storage and image information systems. A primary diagnosis workstation must support rapid selection and viewing of patient examination folders. The user must easily and rapidly sequence through a stack of examinations. Activities such as printing films, archiving images, and retrieving older examinations must be initiated easily, without interfering with the diagnostic use of the workstation. Some of these functions are executed by the workstation itself while others are performed by service nodes on the PACS network. The workstation's user interface must make the architecture of the system transparent, providing access to the services while concealing the complexity of their accomplishment. This paper discusses the approach taken to the user interface of a commercial PACS primary diagnosis workstation. This workstation may be configured as an entry-level PACS or as a single workstation in a very complex system. Local image storage, retrieval, archiving and display functions will be described. Networking with modalities, image storage systems and image management systems will also be discussed.

  16. Internationalization of healthcare applications: a generic approach for PACS workstations.

    Science.gov (United States)

    Hussein, R; Engelmann, U; Schroeter, A; Meinzer, H P

    2004-01-01

    Along with the revolution of information technology and the increasing use of computers world-wide, software providers recognize the emerging need for internationalized, or global, software applications. The importance of internationalization comes from its benefits such as addressing a broader audience, making the software applications more accessible, easier to use, more flexible to support and providing users with more consistent information. In addition, some governmental agencies, e.g., in Spain, accept only fully localized software. Although the healthcare communication standards, namely, Digital Imaging and Communication in Medicine (DICOM) and Health Level Seven (HL7) support wide areas of internationalization, most of the implementers are still protective about supporting the complex languages. This paper describes a generic internationalization approach for Picture Archiving and Communication System (PACS) workstations. The Unicode standard is used to internationalize the application user interface. An encoding converter was developed to encode and decode the data between the rendering module (in Unicode encoding) and the DICOM data (in ISO 8859 encoding). An integration gateway was required to integrate the internationalized PACS components with the different PACS installations. To introduce a pragmatic example, the described approach was applied to the CHILI PACS workstation. The approach has enabled the application to handle the different internationalization aspects transparently, such as supporting complex languages, switching between different languages at runtime, and supporting multilingual clinical reports. In the healthcare enterprises, internationalized applications play an essential role in supporting a seamless flow of information between the heterogeneous multivendor information systems.

  17. First results of Herschel-PACS observations of Neptune

    NARCIS (Netherlands)

    Lellouch, E.; Hartogh, P.; Feuchtgruber, H.; Vandenbussche, B.; de Graauw, Th.; Moreno, R.; Jarchow, C.; Cavalie, T.; Orton, G.; Banaszkiewicz, M.; Blecka, M. I.; Bockelee-Morvan, D.; Crovisier, J.; Encrenaz, T.; Fulton, T.; Kueppers, M.; Lara, L. M.; Lis, D. C.; Medvedev, A. S.; Rengel, M.; Sagawa, H.; Swinyard, B.; Szutowicz, S.; Bensch, F.; Bergin, E.; Billebaud, F.; Biver, N.; Blake, G. A.; Blommaert, J. A. D. L.; Cernicharo, J.; Courtin, R.; Davis, G. R.; Decin, L.; Encrenaz, P.; Gonzalez, A.; Jehin, E.; Kidger, M.; Naylor, D.; Portyankina, G.; Schieder, R.; Sidher, S.; Thomas, N.; de Val-Borro, M.; Verdugo, E.; Waelkens, C.; Aarts, H.; Comito, C.; Kawamura, J. H.; Maestrini, A.; Peacocke, T.; Teipen, R.; Tils, T.; Wildeman, K.; Walker, H.; Blake, G.A.

    2010-01-01

    We report on the initial analysis of a Herschel-PACS full range spectrum of Neptune, covering the 51-220 mu m range with a mean resolving power of similar to 3000, and complemented by a dedicated observation of CH(4) at 120 mu m. Numerous spectral features due to HD (R(0) and R(1)), H(2)O, CH(4),

  18. Design and optimizing factors of PACS network architecture

    International Nuclear Information System (INIS)

    Tao Yonghao; Miao Jingtao

    2001-01-01

    Objective: Exploring the design and optimizing factors of picture archiving and communication system (PACS) network architecture. Methods: Based on the PACS of shanghai first hospital to performed the measurements and tests on the requirements of network bandwidth and transmitting rate for different PACS functions and procedures respectively in static and dynamic network traffic situation, utilizing the network monitoring tools which built-in workstations and provided by Windows NT. Results: No obvious difference between switch equipment and HUB when measurements and tests implemented in static situation except route which slow down the rate markedly. In dynamic environment Switch is able to provide higher bandwidth utilizing than HUB and local system scope communication achieved faster transmitting rate than global system. Conclusion: The primary optimizing factors of PACS network architecture design include concise network topology and disassemble tremendous global traffic to multiple distributed local scope network communication to reduce the traffic of network backbone. The most important issue is guarantee essential bandwidth for diagnosis procedure of medical imaging

  19. Evolutionistic or revolutionary paths? A PACS maturity model for strategic situational planning.

    NARCIS (Netherlands)

    Wetering, R. van de; Batenburg, R.; Lederman, R.

    2010-01-01

    PURPOSE: While many hospitals are re-evaluating their current Picture Archiving and Communication System (PACS), few have a mature strategy for PACS deployment. Furthermore, strategies for implementation, strategic and situational planning methods for the evolution of PACS maturity are scarce in the

  20. Impact of PAC Fines in Fouling of Polymeric and Ceramic Low-Pressure Membranes for Drinking Water Treatment.

    Science.gov (United States)

    Oligny, Laurent; Bérubé, Pierre R; Barbeau, Benoit

    2016-07-07

    This study assessed the issue of membrane fouling in a Hybrid Membrane Process (HMP) due to the export of powdered activated carbon (PAC) fines from a pretreatment contactor. Two parallel pilot-scale ceramic and polymeric membranes were studied. Reversible and irreversible foulings were measured following three cleaning procedures: Physical backwashing (BW), chemically enhanced backwashing (CEB) and Clean-in-Place (CIP). The impacts on fouling of membrane type, operation flux increase and the presence/absence of the PAC pretreatment were investigated. Membranes without pretreatment were operated in parallel as a control. In addition, CIP washwaters samples were analyzed to measure organic and inorganic foulants removed from the membranes. It was observed that for the polymeric membranes, fouling generally increased with the presence of the PAC pretreatment because of the export of fines. On the contrary, the ceramic membranes were not significantly impacted by their presence. The analysis of CIP washwaters showed a greater total organic carbon (TOC) content on membranes with a PAC pretreatment while no similar conclusion could be made for inorganic foulants.

  1. Impact of PAC Fines in Fouling of Polymeric and Ceramic Low-Pressure Membranes for Drinking Water Treatment

    Directory of Open Access Journals (Sweden)

    Laurent Oligny

    2016-07-01

    Full Text Available This study assessed the issue of membrane fouling in a Hybrid Membrane Process (HMP due to the export of powdered activated carbon (PAC fines from a pretreatment contactor. Two parallel pilot-scale ceramic and polymeric membranes were studied. Reversible and irreversible foulings were measured following three cleaning procedures: Physical backwashing (BW, chemically enhanced backwashing (CEB and Clean-in-Place (CIP. The impacts on fouling of membrane type, operation flux increase and the presence/absence of the PAC pretreatment were investigated. Membranes without pretreatment were operated in parallel as a control. In addition, CIP washwaters samples were analyzed to measure organic and inorganic foulants removed from the membranes. It was observed that for the polymeric membranes, fouling generally increased with the presence of the PAC pretreatment because of the export of fines. On the contrary, the ceramic membranes were not significantly impacted by their presence. The analysis of CIP washwaters showed a greater total organic carbon (TOC content on membranes with a PAC pretreatment while no similar conclusion could be made for inorganic foulants.

  2. Impact of PAC Fines in Fouling of Polymeric and Ceramic Low-Pressure Membranes for Drinking Water Treatment

    Science.gov (United States)

    Oligny, Laurent; Bérubé, Pierre R.; Barbeau, Benoit

    2016-01-01

    This study assessed the issue of membrane fouling in a Hybrid Membrane Process (HMP) due to the export of powdered activated carbon (PAC) fines from a pretreatment contactor. Two parallel pilot-scale ceramic and polymeric membranes were studied. Reversible and irreversible foulings were measured following three cleaning procedures: Physical backwashing (BW), chemically enhanced backwashing (CEB) and Clean-in-Place (CIP). The impacts on fouling of membrane type, operation flux increase and the presence/absence of the PAC pretreatment were investigated. Membranes without pretreatment were operated in parallel as a control. In addition, CIP washwaters samples were analyzed to measure organic and inorganic foulants removed from the membranes. It was observed that for the polymeric membranes, fouling generally increased with the presence of the PAC pretreatment because of the export of fines. On the contrary, the ceramic membranes were not significantly impacted by their presence. The analysis of CIP washwaters showed a greater total organic carbon (TOC) content on membranes with a PAC pretreatment while no similar conclusion could be made for inorganic foulants. PMID:27399788

  3. Care dependency in nursing home : a psychometric study

    NARCIS (Netherlands)

    Lohrmann, C; Balzer, K; Dijkstra, Ate; Dassen, T

    The Dutch Care Dependency Scale, an instrument for the assessment of a patient's care dependency, has been translated into German. The purpose of this study was to examine the reliability and validity of the German version of the scale. The 15-item scale has been developed for the use in nursing

  4. Experimental study of the dependence of beam current on injection ...

    Indian Academy of Sciences (India)

    The ion current from an electron cyclotron resonance (ECR) heavy ion source depends on the confining axial and radial magnetic fields. Some efforts were made by earlier workers to investigate magnetic field scaling on the performance of the ECR source. In order to study the dependence of the ion current on the injection ...

  5. Experimental study of the dependence of beam current on injection ...

    Indian Academy of Sciences (India)

    Abstract. The ion current from an electron cyclotron resonance (ECR) heavy ion source depends on the confining axial and radial magnetic fields. Some efforts were made by earlier workers to investigate magnetic field scaling on the performance of the ECR source. In order to study the dependence of the ion current on the ...

  6. From shared data to sharing workflow: Merging PACS and teleradiology

    International Nuclear Information System (INIS)

    Benjamin, Menashe; Aradi, Yinon; Shreiber, Reuven

    2010-01-01

    Due to a host of technological, interface, operational and workflow limitations, teleradiology and PACS/RIS were historically developed as separate systems serving different purposes. PACS/RIS handled local radiology storage and workflow management while teleradiology addressed remote access to images. Today advanced PACS/RIS support complete site radiology workflow for attending physicians, whether on-site or remote. In parallel, teleradiology has emerged into a service of providing remote, off-hours, coverage for emergency radiology and to a lesser extent subspecialty reading to subscribing sites and radiology groups. When attending radiologists use teleradiology for remote access to a site, they may share all relevant patient data and participate in the site's workflow like their on-site peers. The operation gets cumbersome and time consuming when these radiologists serve multi-sites, each requiring a different remote access, or when the sites do not employ the same PACS/RIS/Reporting Systems and do not share the same ownership. The least efficient operation is of teleradiology companies engaged in reading for multiple facilities. As these services typically employ non-local radiologists, they are allowed to share some of the available patient data necessary to provide an emergency report but, by enlarge, they do not share the workflow of the sites they serve. Radiology stakeholders usually prefer to have their own radiologists perform all radiology tasks including interpretation of off-hour examinations. It is possible with current technology to create a system that combines the benefits of local radiology services to multiple sites with the advantages offered by adding subspecialty and off-hours emergency services through teleradiology. Such a system increases efficiency for the radiology groups by enabling all users, regardless of location, to work 'local' and fully participate in the workflow of every site. We refer to such a system as SuperPACS.

  7. Online gaming dependency: a preliminary study in China.

    Science.gov (United States)

    Peng, Wei; Liu, Ming

    2010-06-01

    Based on theories and previous studies on problematic Internet use, we propose a model to better understand the contributors to and consequences of online gaming dependency. A preliminary study was conducted through a survey of online gamers in China. The results of path analysis found that maladaptive cognitions, shyness, and depression are positively related to online gaming dependency. Online gaming dependency was also positively related to different types of negative life outcomes. The findings of this study have implications for the prevention and treatment of addictive online gaming.

  8. The Study of early maladaptive Schemas in Men Dependent on Drugs and those Not Dependent

    Directory of Open Access Journals (Sweden)

    MR Firoozi

    2015-11-01

    Full Text Available Introduction and Objectives of the Study Dependence on drugs is a prevalent problem throughout the world, in general and in Iran, in particular. Such a phenomenon is associated with numerous negative consequences. Given the changes in the consumption patterns in different countries, especially in Iran, and the abuse of drugs, identifying the factors which may pave the way for drug abuse is absolutely essential, which can be taken into account in setting the objectives of therapy programs. Cognizant of this, the present study has sought to study early maladaptive schemas in men dependent on drugs and those that are not. Materials and Method: The research design adopted in the present study was causal-comparative. The populaiton of interest was all the men dependent on drugs in the city of Yasouj, who had presented to recovery centers affiliated to welfare organization and Yasouj University of Medical Sciences in the year 2014 and were undergoing treatment. Using multi-stage cluster sampling, initially out of 23 centers for recovery programs, four centers were randomly chosen. Following that, out of each center, 20 and in total, 80 clients were chosen as the sample through convenience sampling. In addition, 80 men not dependent on drugs were chosen through matching with the sample dependent on drugs in terms of age, gender and locality. For the purpsoe of measuing early maladaptive schemas, we made use of the short version of Young’s early maladaptive Schemas Questionnaire. In order to determine the prevalent schemas in men dependent on drugs and those not dependent and the difference between the two groups, use was made of independent-sample t-test and effect size (d. Findings: The findings suggest that mean values of those dependent on drugs in all the schemas in quesiton were significantly higher than those of men not dependent. Although the difference in effect size of all schemas fell in the domain of the large effect, the largest

  9. Study of Cu-Al-Zn alloys hardness temperature dependence

    International Nuclear Information System (INIS)

    Kurmanova, D.T.; Skakov, M.K.; Melikhov, V.D.

    2001-01-01

    In the paper the results of studies for the Cu-Al-Zn ternary alloys hardness temperature dependence are presented. The method of 'hot hardness' has been used during study of the solid state phase transformations and under determination of the hot stability boundaries. Due to the samples brittleness a hardness temperature dependence definition is possible only from 350-400 deg. C. Sensitivity of the 'hot hardness' method is decreasing within high plasticity range, so the measurements have been carried out only up to 700-800 deg. C. It is shown, that the alloys hardness dependence character from temperature is close to exponential one within the certain structure modification existence domain

  10. K2 and Herschel/PACS photometry of irregular satellites

    Science.gov (United States)

    Pal, Andras; Kiss, Csaba; Molnar, Laszlo; Mueller, Thomas G.; Sarneczky, Krisztian; Szabo, Robert; Kiss, Laszlo L.; Szabo, Gyula M.

    2016-10-01

    The combination of optical and far-infrared photometric measurements yields an unambiguous method for characterizing the basic physical and surface properties of minor bodies in the Solar System. In principle, an object with a certain visible brightness can either be an object with a small but bright or a large but dim surface. To resolve this issue, conducting thermal emission measurements can also be acquired since both larger and dimmer objects have higher infrared radiations. In addition, the precise modelling of thermal emission should certainly take into account the rotation period of these bodies - otherwise the presence of surface thermal inertia can result in inaccurate conclusions regarding to the physical size and albedo.Since early 2014, Kepler Space Telescope surveys fields close to the Ecliptic in a framework of quarterly campaigns of the K2 initiative. This program makes possible to continuously observe Solar System bodies during this period of 80-90 days and hence provide an uninterrupted photometric series of moving Solar System objects down to the magnitude range of R = 23.5. This instrument hence an ideal observatory now for Solar System studies. Due to the fact that the expected rotational periods of these objects are commensurable to the diurnal characteristics of ground-based observations, such uninterrupted light curves are rather valuable for the accurate determination of rotational characteristics - including the physical rotation period, the amplitude and the confirmation of the presence of double- or multiple peaked features.In this presentation we summarize our results of current K2 and legacy Herschel/PACS observations regarding to some of the irregular satellites of Uranus and Neptune, namely Caliban, Sycorax, Prospero, Setebos and Nereid. By comparing these results with similar kind of observations for trans-Neptunian objects (see Kiss et al., this DPS meeting), one can conclude how the formation and evolution of the outer Solar

  11. Uma avaliação do Programa de Aceleração do Crescimento (PAC no estado da Bahia (2007-10 Una evaluación del Programa de Aceleración del Crecimiento (PAC en el Estado de la Bahia - Brasil (2007-10 An evaluation of the Growth Acceleration Program (PAC in the state of Bahia - Brazil (2007-10

    Directory of Open Access Journals (Sweden)

    Aliger dos Santos Pereira

    2013-02-01

    Full Text Available O artigo analisa os principais empreendimentos de infraestrutura (logística, energética e social e urbana do Programa de Aceleração do Crescimento (PAC no período de 2007 a 2010. A problemática do estudo foi: como o planejamento do PAC baiano contribuiu para o desenvolvimento do Estado? O artigo demonstra, por meio de dados quantitativos, o impacto e o desempenho do PAC para o desenvolvimento da Bahia. Para a realização dessa abordagem quantitativa, informações foram extraídas de dados secundários. Conclui-se que, em média, 76,93% dos projetos do PAC baiano não foram finalizados, mas, mesmo assim, ao associá-lo ao Produto Interno Bruto (PIB, utilizando uma simulação regressiva, antes, durante e depois dos anos de 2007 até 2010, percebe-se sua influência e interferência no processo de crescimento regional da Bahia.El trabajo analiza las principales construcciones de infraestructura (logística, energética y social y urbana del Programa de Aceleración del Crecimiento (PAC en el período comprendido entre 2007 y 2010. El problema del estudio fue: ¿cómo la planificación del PAC (Bahia ha contribuido para el desarrollo del estado? El artículo muestra, a través de datos cuantitativos, el impacto y el rendimiento del PAC para el desarrollo de la Bahia. Para llevar a este enfoque, se utilizaron datos secundarios. Si concluye que en promedio 76,93% de los proyectos de PAC (Bahia no fue finalizado. Al asociar el PAC (Bahia con su Producto Interno Bruto (PIB a través de una simulación regresiva (antes, durante y después de los años de 2007 a 2010, es posible comprobar que el PAC influencia e interfiere en el proceso de crecimiento regional en Bahia.The article reviews the development of the main infrastructure aspects (logistics, energy and social and urban of the Growth Acceleration Program (PAC in the period 2007 to 2010. The problem of the study was: how did the PAC contribute to the development of Bahia State? The article

  12. Effect of PACS/CR on cost of care and length of stay in a medical intensive care unit

    Science.gov (United States)

    Langlotz, Curtis P.; Kundel, Harold L.; Brikman, Inna; Pratt, Hugh M.; Redfern, Regina O.; Horii, Steven C.; Schwartz, J. Sanford

    1996-05-01

    Our purpose was to determine the economic effects associated with the introduction of PACS and computed radiology (CR) in a medical intensive care unit (MICU). Clinical and financial data were collected over a period of 6 months, both before and after the introduction of PACS/CR in our medical intensive care unit. Administrative claims data resulting from the MICU stay of each patient enrolled in our study were transferred online to our research database from the administrative databases of our hospital and its affiliated clinical practices. These data included all charge entries, sociodemographic data, admissions/discharge/transfer chronologies, ICD9 diagnostic and procedure codes, and diagnostic related groups. APACHE III scores and other case mix adjusters were computed from the diagnostic codes, and from the contemporaneous medical record. Departmental charge to cost ratios and the Medicare Resource-Based Relative Value Scale fee schedule were used to estimate costs from hospital and professional charges. Data were analyzed using both the patient and the exam as the unit of analysis. Univariate analyses by patient show that patients enrolled during the PACS periods were similar to those enrolled during the Film periods in age, sex, APACHE III score, and other measures of case mix. No significant differences in unadjusted median length of stay between the two Film and two PACS periods were detected. Likewise, no significant differences in unadjusted total hospital and professional costs were found between the Film and PACS periods. In our univariate analyses by exam, we focused on the subgroup of exams that had triggered primary clinical actions in any period. Those action-triggering exams were divided into two groups according to whether the referring clinician elected to obtain imaging results from the workstation or from the usual channels. Patients whose imaging results were obtain from the workstation had significantly lower professional costs in the 7 days

  13. Incremental picture archiving and communication system (PACS) - an appraisal

    International Nuclear Information System (INIS)

    Nagle, K.

    2000-01-01

    Digital storage phosphor radiography is slowly being introduced in Australia with more sites making the conversion from film/screen to computed radiography or a fully integrated Picture Archiving and Communication System (PACS). St Vincent's Hospital, Melbourne (SVHM) introduced partial PACS for general radiography in June 1996. This involved networking two Fuji CR Image Plate Readers and an existing Kodak KESPR400 Reader with viewing stations strategically placed in Medical Imaging, Casualty and the Intensive and Coronary Care units. No long-term storage device or archive facility was purchased. This installation coincided with the relocation of the Medical Imaging Department (MID) to a fully equipped new site as well as the introduction of the Kestral Radiology Management System. The transition has involved significant changes to the department's design, workflow and the radiographers' work practices. Copyright (1999) Australian Institute of Radiography

  14. Peligros del átomo pacífico

    Directory of Open Access Journals (Sweden)

    Juan Zarco de Gea

    1962-07-01

    Full Text Available Expuestas en el artículo anterior las ventajas que el hombre puede obtener del uso de la energía atómica para fines pacíficos: industria, agricultura, medicina, investigación científica, etc., parece oportuno examinar ahora el reverso de la medalla y estudiar los inconvenientes de ese mismo uso pacífico de las fuerzas atómicas; inconvenientes, dicho sea de paso, que también existen en el aprovechamiento de otras fuerzas naturales, físicas o químicas, en las minas, fábricas, laboratorios y otras muchas empresas de toda índole; pero tratándose de las energías nucleares entran en juego factores nuevos y especiales, que llevan el asunto a terrenos diferentes: moral, político, de salud pública, etc.

  15. PACS to increase speed and reduce costs of diagnosis

    International Nuclear Information System (INIS)

    Anon.

    1993-01-01

    According to the product claims, digital diagnostic images will be retrievable immediately and anywhere by users of the Picture Archiving and Communication System (PACS). US Army and US Air Force expect the system to allow annual cost savings of the order of 45 million US dollars in their own hospitals. It comprises a wide range of highly sophisticated background technologies developed by Siemens Gammasonics and Loral Western Development Labs. (orig.) [de

  16. Application service providers: an alternative approach to PACS implementation

    OpenAIRE

    Reiner, B; Siegel, E

    2001-01-01

    Several impediments have delayed the adoption of filmless imaging by the majority of radiology practitioners. These factors include concerns for technology obsolescence, limited available capital, and lack of existing information technology (IT) infrastructure and experienced personnel. Application service providers (ASPs) have begun to emerge as an alternative approach to the more traditional acquisition of picture archiving and communication (PAC) systems. This approach offers the prospecti...

  17. Learning in clinical practice: findings from CT, MRI and PACS

    OpenAIRE

    Sinozic, Tanja

    2014-01-01

    This thesis explores learning in clinical practice in the cases of CT, MRI and PACS in\\ud UK hospitals. It asks the questions of how and why certain evolutionary features of\\ud technology condition learning and change in medical contexts.\\ud Using an evolutionary perspective of cognitive and social aspects of technological\\ud change, this thesis explores the relationships between technology and organisational\\ud learning processes of intuition, interpretation, integration and institutionalisa...

  18. Integration of implant planning workflows into the PACS infrastructure

    Science.gov (United States)

    Gessat, Michael; Strauß, Gero; Burgert, Oliver

    2008-03-01

    The integration of imaging devices, diagnostic workstations, and image servers into Picture Archiving and Communication Systems (PACS) has had an enormous effect on the efficiency of radiology workflows. The standardization of the information exchange between the devices with the DICOM standard has been an essential precondition for that development. For surgical procedures, no such infrastructure exists. With the increasingly important role computerized planning and assistance systems play in the surgical domain, an infrastructure that unifies the communication between devices becomes necessary. In recent publications, the need for a modularized system design has been established. A reference architecture for a Therapy Imaging and Model Management System (TIMMS) has been proposed. It was accepted by the DICOM Working Group 6 as the reference architecture for DICOM developments for surgery. In this paper we propose the inclusion of implant planning systems into the PACS infrastructure. We propose a generic information model for the patient specific selection and positioning of implants from a repository according to patient image data. The information models are based on clinical workflows from ENT, cardiac, and orthopedic surgery as well as technical requirements derived from different use cases and systems. We show an exemplary implementation of the model for application in ENT surgery: the selection and positioning of an ossicular implant in the middle ear. An implant repository is stored in the PACS. It makes use of an experimental implementation of the Surface Mesh Module that is currently being developed as extension to the DICOM standard.

  19. Picture archiving and communication systems (PACS) in clinical practice

    International Nuclear Information System (INIS)

    Carreno Pedemonte, J.C.; Piqueras Pardellans, J.; Lucaya Layret, J.

    1994-01-01

    Picture archiving and communication systems (PACS) were developed as a technological response to the complex management of the growing amount of information generated by the different diagnostic imaging methods. This article documents the process of the progressive implementation, starting in January 1991, of the first complete PACS installed in our country. The system installed in our center is composed of acquisition modules for all the imaging methods (computed radiography, ultrasound, computed tomography, digital fluoroscopy and magnetic resonance), a central processing unit, an automatic optical disk for storage and a network of image viewing and diagnostic stations. The preliminary results obtained with its implementation demonstrate that PACS provide a series of functional advantages, especially at the image storage and display levels. In spite of these conveniences, the present high costs of acquisition and maintenance, together with certain technical problems as a result of its complexity, will signify that its generalized application for all imaging methods will not become a reality at most centers in the near future

  20. Automatically measuring brain ventricular volume within PACS using artificial intelligence.

    Science.gov (United States)

    Yepes-Calderon, Fernando; Nelson, Marvin D; McComb, J Gordon

    2018-01-01

    The picture archiving and communications system (PACS) is currently the standard platform to manage medical images but lacks analytical capabilities. Staying within PACS, the authors have developed an automatic method to retrieve the medical data and access it at a voxel level, decrypted and uncompressed that allows analytical capabilities while not perturbing the system's daily operation. Additionally, the strategy is secure and vendor independent. Cerebral ventricular volume is important for the diagnosis and treatment of many neurological disorders. A significant change in ventricular volume is readily recognized, but subtle changes, especially over longer periods of time, may be difficult to discern. Clinical imaging protocols and parameters are often varied making it difficult to use a general solution with standard segmentation techniques. Presented is a segmentation strategy based on an algorithm that uses four features extracted from the medical images to create a statistical estimator capable of determining ventricular volume. When compared with manual segmentations, the correlation was 94% and holds promise for even better accuracy by incorporating the unlimited data available. The volume of any segmentable structure can be accurately determined utilizing the machine learning strategy presented and runs fully automatically within the PACS.

  1. Assessing the impact of computed radiography and PACS

    International Nuclear Information System (INIS)

    Hedgcock, M.W. Jr.; Kehr, K.

    1989-01-01

    The authors' institution is a VA pilot center for total digital imaging and PACS. They are gathering quantitative service delivery and cost data before, during, and after stepwise implementation of computed radiography and PACS at our institution to define the impact on imaging service delivery. They designed a simple audit method using the X-ray request and time clocks to determine patient waiting time, imaging time, film use, image availability to the radiologist, matching of current with previous images, image availability to clinicians, and time to final interpretation. Their department model is a multichannel, multiserver patient queue. Their current radiograph file is space limited. Their preimplementation audit showed some long waiting times (40 minutes, average 20) and immediate retrieval of prior films in only 42% of cases, with an average retrieval time of 22 hours. Computed radiography and the optical archive have the potential to improve these figures. The audit will be ongoing and automated as implementation of PACS progresses, to measure service improvement and learning curve with the new equipment. This paper presents the audit format and baseline preimplementation figures

  2. Polish Adaptation And Validation Of The Physical Appearance Comparison Scale (Pacs) - An Analysis Among Young People In Late Adolescence In The Context Of Obesity.

    Science.gov (United States)

    Dzielska, Anna; Mazur, Joanna; Nałęcz, Hanna; Oblacińska, Anna; Strucińska, Małgorzata

    2017-01-01

    The PACS scale is a tool which is widely used in foreign studies to evaluate the tendency towards appearance comparisons in social situations. People inclined to make such comparisons reveal a higher level of dissatisfaction with their body and a higher inclination towards problem eating. The main purpose of the study was to adapt the PACS scale. A factor structure assessment and reliability analysis of the Polish version was carried out. The correlation between PACS and pubertal development indicators, the body mass index and psycho-social factors and eating behaviours were evaluated as part of the validity analysis. The data were derived from the Internet-based study of problem eating behaviours conducted by the Institute of Mother and Child during the 2014/2015 school year. The analyses covered 1285 second grade upper secondary school students (47.2% boys). The mean age was 17.59 years (SD=0.39). An exploratory and confirmatory factor analysis of the PACS questionnaire was performed. Using the Kruskal-Wallis test or the Pearson's r correlation, the association between (PACSPL) and perceived pubertal timing, BMI, the body image (BIS), self-perception of body mass, self-esteem (RSES), self-esteem in social relations (SPPA-SSE), problem eating behaviours (TFEQ-13) were evaluated. The linear regression method was used to estimate the impact of PACS-PL on selected variables in the BMI groups in order to investigate of the moderation effect. The shortened 3-item Polish version of the scale (PACS-PL) was considered optimal. It is characterized by high reliability (Cronbach's α=0.868), and the main factor explains 79.1% of the variance of the scale results. The model also shows high values of fit indicators: χ2 = 1.144 (df=1, p=0.285), GFI=0.999, AGFI=0.996, CFI=1.000, NFI=0.999, TLI-1.000, RMSEA=0.011. Girls display a stronger tendency to compare their appearance with others. The PACS-PL scale demonstrates the expected correlations with developmental, psycho

  3. Effects of posture-related auditory cueing (PAC) program on muscles activities and kinematics of the neck and trunk during computer work.

    Science.gov (United States)

    Yoo, Won-Gyu; Park, Se-Yeon

    2015-01-01

    The etiology of the neck and back discomfort are highly associated with abnormal static posture such as forward head posture and flexed relaxed posture; such postures are regarded as the risk factors for work-related musculoskeletal disorders. Although, various ergonomic chairs and devices have been developed for computer workers, there are few reports of software that can alert users to their posture or work hours. Purpose of the present study was to investigate the difference of kinematics of the neck and trunk segments as well as muscular activation between condition with and without posture related auditory cueing. Twelve male computer workers were recruited in this study. A posture related auditory cueing (PAC) program used a media file that generated postural correction cue at intervals of 300 seconds. Surface electromyography was used to measure the activity of the erector spine and upper trapezius. Kinematic data were obtained using an ultrasonic three dimensional movement analysis system. The results showed that the means of trunk flexion and forward head angle were significantly reduced with PAC. The muscular activity of the erector spine and upper trapezius was significantly higher with the PAC and significantly lower without the PAC. Our findings suggested that the software providing PACs is an ergonomic device with positive effects for preventing habitual poor posture and potential for widespread practical usage.

  4. Minimally Clinically Important Change in the Activity Measure for Post-Acute Care (AM-PAC), a Generic Patient-Reported Outcome Tool, in People With Low Back Pain.

    Science.gov (United States)

    Lee, Natalie; Thompson, Nicolas R; Passek, Sandra; Stilphen, Mary; Katzan, Irene L

    2017-11-01

    The Activity Measure for Post-Acute Care (AM-PAC) is a generic metric of patient-reported functional status. The minimal clinically important difference (MCID) in the AM-PAC score has not been determined. The study objective was to determine the MCID for AM-PAC in people with low back pain. This was a retrospective cohort study. Anchor-based and distribution-based methods were used to estimate the MCID. The Modified Low Back Pain Disability Questionnaire was used as the anchor. Adults who had a primary ICD-9 code for low back pain in at least 1 outpatient physical therapist visit during an episode of care and who completed both the AM-PAC and the Modified Low Back Pain Disability Questionnaire in at least 2 visits during the care episode were included. The MCID was calculated for the AM-PAC basic mobility version as well its adapted version, which the Cleveland Clinic uses for patients 65 years old or older. A total of 1,271 participants were eligible for study. For the AM-PAC basic mobility version, anchor-based methods yielded MCID estimates of between 3.4 and 5.1, whereas distribution-based methods yielded estimates of 1.7 to 4.2. The minimal detectable change (MDC) for the AM-PAC basic mobility version was 3.3. For the adapted AM-PAC basic mobility version, the MCID was estimated to be between 2.9 and 4.0 via anchor-based methods and between 1.2 to 3.5 via distribution-based methods. The MDC for the adapted AM-PAC basic mobility version was 3.5. The estimated MCID was designed for people with low back pain only. The MCID ranged from 3.3 to 5.1 for the AM-PAC basic mobility version and 3.5 to 4 for the adapted version, with the MDC as the lower limit. Changes in the AM-PAC for people with low back pain may be interpreted using the estimated MCID. Future studies are needed to determine the AM-PAC MCID for populations other than those with low back pain. © 2017 American Physical Therapy Association

  5. Removal of a synthetic organic chemical by PAC-UF systems. II: Model application.

    Science.gov (United States)

    Matsui, Y; Colas, F; Yuasa, A

    2001-02-01

    This paper describes several application potentials with a recently developed model for predicting the synthetic organic chemical (SOC) removal by powdered activated carbon (PAC) adsorption during ultrafiltration (UF) and discusses the removal mechanism. The model was successfully applied, without any modification, to dead-end mode operation as well as to cross-flow mode operation, validating the assumption of the internal diffusion control mechanism and the continuously-stirred-tank-reactor (CSTR) concept. Even when UF was operated in a cross-flow mode, PAC added was re-circulating in suspension for only a short time. Then, solute uptake took place mostly by PAC immobilized in membrane tubes not only for dead-end operation but also for cross-flow operation. Therefore, cross-flow operation did not have any advantage regarding the SOC mass transfer on PAC in UF loop over dead-end operation. The model simulation implied that pulse PAC addition at the beginning of filtration cycle resulted better SOC removal than continuous PAC addition. However, for the pulse PAC addition mode, the model predicted somewhat lower effluent SOC concentration than the observed values, and the benefit of pulse PAC application in terms of reducing SOC over its continuous dosage was not confirmed. Longer detention time of PAC dosed in a pulse than continuously dosed PAC could possibly further decrease internal diffusivity.

  6. Study of excitation energy dependence of nuclear level density parameter

    International Nuclear Information System (INIS)

    Mohanto, G.; Nayak, B.K.; Saxena, A.

    2016-01-01

    In the present study, we have populated CN by fusion reaction and excitation energy of the intermediate nuclei is determined after first chance α-emission to investigate excitation energy dependence of the NLD parameter. Evaporated neutron spectra were measured following alpha evaporation for obtaining NLD parameter for the reaction 11 B + 197 Au, populating CN 208 Po. This CN after evaporating an α-particle populates intermediate nucleus 204 Pb. The 204 Pb has magic number of Z=82. Our aim is to study the excitation energy dependence of NLD parameter for closed shell nuclei

  7. Acceptability of picture archiving and communication system (PACS) among hospital healthcare personnel based on a unified theory of acceptance and use of technology.

    Science.gov (United States)

    Ahmadi, Maryam; Mehrabi, Nahid; Sheikhtaheri, Abbas; Sadeghi, Mojtaba

    2017-09-01

    The picture archiving and communication system (PACS) is a healthcare system technology which manages medical images and integrates equipment through a network. There are some theories about the use and acceptance of technology by people to describe the behavior and attitudes of end users towards information technologies. We investigated the influential factors on users' acceptance of PACS in the military hospitals of Tehran. In this applied analytical and cross-sectional study, 151 healthcare employees of military hospitals who had experience in using the PACS system were investigated. Participants were selected by census. The following variables were considered: performance expectancy, efforts expectancy, social influence, facilitating conditions and behavioral intention. Data were gathered using a questionnaire. Its validity and reliability were approved by a panel of experts and was piloted with 30 hospital healthcare staff (Cronbach's alpha =0.91). Spearman correlation coefficient and multiple linear regression analysis were used in analyzing the data. Expected performance, efforts expectancy, social impact and facilitating conditions had a significant relationship with behavioral intention. The multiple regression analysis indicated that only performance expectancy can predict the user's behavioral intentions to use PACS technology. Performance and effort expectancies are quite influential in accepting the use of PACS in hospitals. All healthcare personnel should become aware that using such technology is necessary in a hospital. Knowing the influencing factors that affect the acceptance of using new technology can help in improving its use, especially in a healthcare system. This can improve the offered healthcare services' quality.

  8. Temperature dependent damping studies of Ni–Mn–Ga polymer ...

    Indian Academy of Sciences (India)

    Administrator

    Bull. Mater. Sci., Vol. 34, No. 4, July 2011, pp. 739–743. © Indian Academy of Sciences. 739. Temperature dependent damping studies of Ni–Mn–Ga polymer composites ... martensite transformation (Ullakko et al 1996; Mullner and Ullakko 1998 ... on twin boundaries (Kokorin et al 1996; Segui et al 2004;. Vijay Kumar ...

  9. Study of nuclear level density parameter and its temperature dependence

    International Nuclear Information System (INIS)

    Nasrabadi, M. N.; Behkami, A. N.

    2000-01-01

    The nuclear level density ρ is the basic ingredient required for theoretical studies of nuclear reaction and structure. It describes the statistical nuclear properties and is expressed as a function of various constants of motion such as number of particles, excitation energy and angular momentum. In this work the energy and spin dependence of nuclear level density will be presented and discussed. In addition the level density parameter α will be extracted from this level density information, and its temperature and mass dependence will be obtained

  10. Perturbed-angular-correlation study of the electric-field gradient in 181Hf-doped and implanted indium sesquioxide

    International Nuclear Information System (INIS)

    Renteria, M.; Requejo, F.G.; Bibiloni, A.G.; Pasquevich, A.F.; Shitu, J.; Freitag, K.

    1997-01-01

    We studied the hyperfine interactions of 181 Ta in In 2 O 3 by means of perturbed-angular-correlation (PAC) measurements. We prepared thin films of indium sesquioxide with different degrees of initial amorphism and implanted them with 181 Hf. Chemically prepared indium-sesquioxide powder samples were also made starting from neutron-irradiated HfCl 4 , which provides the 181 Hf PAC probes. PAC experiments were performed on each sample at room temperature, after each step of annealing programs at increasing temperatures up to the full crystallization of the samples. The results indicate that the PAC probe occupies preferentially the axially symmetric cation site. Point-charge-model calculations were performed. The calculated asymmetry parameters η were compared with those obtained in 181 Hf PAC experiments performed also on other binary oxides, showing that the symmetry of the electric-field-gradient (EFG) tensor at 181 Ta cation sites in binary oxides is mainly determined by the nearest-neighbor oxygen-ion distribution around the probe. Comparisons of the experimental results in bixbyites obtained for both PAC probes, 111 Cd and 181 Ta, show that the local EFG in bixbyites, are strongly dependent on the geometry of the sites and the electronic configuration of the probes. copyright 1997 The American Physical Society

  11. Development of hospital-integrated large-scale PACS in Seoul National University Hospital

    Science.gov (United States)

    Kim, JongHyo; Yeon, Kyoung M.; Han, Man Chung; Lee, Dong Hyuk; Cho, Han I.

    1997-05-01

    The SNUH has started a PACS project with three main goals: to develop a fully hospital-integrated PACS, to develop a cost effective PACS using open systems architecture, and to extend PACS' role to the advanced application such as image guided surgery, multi-media assisted education and research. In order to achieve these goals, we have designed a PACS architecture which takes advantage of client-server computing, high speed communication network, computing power of up-to-date high-end PC, and advanced image compression method. We have installed ATM based communication network in radiology department and in-patient wards, and implemented DICOM compliant acquisition modules, image storage and management servers, and high resolution display workstations based on high-end PC and Microsoft Windows 95 and Windows NT operating systems. The SNUH PACS is in partial scale operation now, and will be expanded to full scale by the end of 1998.

  12. Lessons learned from a whole hospital PACS installation. Picture Archiving and Communication System.

    Science.gov (United States)

    Pilling, J R

    2002-09-01

    The Norfolk and Norwich University Hospital has incorporated a fully filmless Picture Archiving and Communication System (PACS) as part of a new hospital provision using PFI funding. The PACS project has been very successful and has met with unanimous acclaim from radiologists and clinicians. A project of this size cannot be achieved without learning some lessons from mistakes and recognising areas where attention to detail resulted in a successful implementation. This paper considers the successes and problems encountered in a large PACS installation.

  13. Photo-dynamics of the lyophilized photo-activated adenylate cyclase NgPAC2 from the amoeboflagellate Naegleria gruberi NEG-M strain

    Science.gov (United States)

    Penzkofer, A.; Tanwar, M.; Veetil, S. K.; Kateriya, S.; Stierl, M.; Hegemann, P.

    2013-09-01

    The absorption and emission spectroscopic behavior of lyophilized photo-activated adenylate cyclase NgPAC2 from the amoeboflagellate Naegleria gruberi NEG-M strain consisting of a BLUF domain (BLUF = Blue Light sensor Using Flavin) and a cyclase homology domain was studied in the dark, during blue-light exposure and after blue-light exposure at a temperature of 4 °C. The BLUF domain photo-cycle dynamics observed for snap-frozen NgPAC2 was lost by lyophilization (no signaling state formation with flavin absorption red-shift). Instead, blue-light photo-excitation of lyophilized NgPAC2 caused sterically restricted Tyr-Tyr cross-linking (o,o‧-ditysosine formation) and partial flavin cofactor reduction.

  14. Integration of computer-aided diagnosis/detection (CAD) results in a PACS environment using CAD-PACS toolkit and DICOM SR

    International Nuclear Information System (INIS)

    Le, Anh H.T.; Liu, Brent; Huang, H.K.

    2009-01-01

    Picture Archiving and Communication System (PACS) is a mature technology in health care delivery for daily clinical imaging service and data management. Computer-aided detection and diagnosis (CAD) utilizes computer methods to obtain quantitative measurements from medical images and clinical information to assist clinicians to assess a patient's clinical state more objectively. CAD needs image input and related information from PACS to improve its accuracy; and PACS benefits from CAD results online and available at the PACS workstation as a second reader to assist physicians in the decision making process. Currently, these two technologies remain as two separate independent systems with only minimal system integration. This paper describes a universal method to integrate CAD results with PACS in its daily clinical environment. The method is based on Health Level 7 (HL7) and Digital imaging and communications in medicine (DICOM) standards, and Integrating the Healthcare Enterprise (IHE) workflow profiles. In addition, the integration method is Health Insurance Portability and Accountability Act (HIPAA) compliant. The paper presents (1) the clinical value and advantages of integrating CAD results in a PACS environment, (2) DICOM Structured Reporting formats and some important IHE workflow profiles utilized in the system integration, (3) the methodology using the CAD-PACS integration toolkit, and (4) clinical examples with step-by-step workflows of this integration. (orig.)

  15. Parallel synthesis and biological evaluation of 837 analogues of procaspase-activating compound 1 (PAC-1).

    Science.gov (United States)

    Hsu, Danny C; Roth, Howard S; West, Diana C; Botham, Rachel C; Novotny, Chris J; Schmid, Steven C; Hergenrother, Paul J

    2012-01-09

    Procaspase-Activating Compound 1 (PAC-1) is an ortho-hydroxy N-acyl hydrazone that enhances the enzymatic activity of procaspase-3 in vitro and induces apoptosis in cancer cells. An analogue of PAC-1, called S-PAC-1, was evaluated in a veterinary clinical trial in pet dogs with lymphoma and found to have considerable potential as an anticancer agent. With the goal of identifying more potent compounds in this promising class of experimental therapeutics, a combinatorial library based on PAC-1 was created, and the compounds were evaluated for their ability to induce death of cancer cells in culture. For library construction, 31 hydrazides were condensed in parallel with 27 aldehydes to create 837 PAC-1 analogues, with an average purity of 91%. The compounds were evaluated for their ability to induce apoptosis in cancer cells, and through this work, six compounds were discovered to be substantially more potent than PAC-1 and S-PAC-1. These six hits were further evaluated for their ability to relieve zinc-mediated inhibition of procaspase-3 in vitro. In general, the newly identified hit compounds are two- to four-fold more potent than PAC-1 and S-PAC-1 in cell culture, and thus have promise as experimental therapeutics for treatment of the many cancers that have elevated expression levels of procaspase-3.

  16. Study of impulse control disorders among women presenting nicotine dependence.

    Science.gov (United States)

    Lejoyeux, Michel; Kerner, Laurent; Thauvin, Isabelle; Loi, Sabrina

    2006-01-01

    Objective. Impulse control disorders (ICDs) include intermittent explosive disorder, kleptomania, trichotillomania, pyromania and pathological gambling. Several studies have showed an association between ICDs and alcohol use disorders. The rate of co-occurrence ICDs and nicotine dependence has never been investigated. We thus assessed the frequency of all ICDs in a population of nicotine-dependent women compared to non-smoking women. We also checked criteria of two other impulsive behaviours, compulsive buying and bulimia. Methods. Five hundred consecutive patients were assessed by a general practitioner in Paris (France). One hundred and twenty-seven women presenting the DSM-IV-R criteria for nicotine dependence were included. They were compared to 127 women consulting the same practitioner but who did not smoke. Diagnosis of ICD (pyromania, kleptomania, trichotillomania, intermittent explosive disorder, pathological gambling) and of bulimia was based on DSM-IV criteria and a modified version of the Minnesota Impulsive Disorders Interview (MIDI). Diagnosis of compulsive buying was made with the McElroy et al. criteria and a specific questionnaire. Cigarette smoking was studied using the Fagerström questionnaire and the DSM-IV-R criteria for nicotine dependence. Alcohol use disorders were assessed with the DSM-IV-R criteria for dependence and the CAGE and the MAST questionnaires. Results. Thirteen patients presented trichotillomania, 22 explosive intermittent disorder and 12 pathological gambling. All these diagnoses were equally frequent in the nicotine-positive and nicotine-negative groups. We found no case of pyromania. Compulsive buying was the most frequent impulse control disorder. It was significantly more frequent in the nicotine-positive group than in the nicotine-negative group (58 vs. 39 cases, P=0.01). Scores of the compulsive buying scale were higher in the nicotine-positive group (4.07 vs. 2.9, P=0.01). None of the patients presented an association

  17. PAC learning algorithms for functions approximated by feedforward networks

    Energy Technology Data Exchange (ETDEWEB)

    Rao, N.S.V.; Protopopescu, V. [Oak Ridge National Lab., TN (United States). Center for Engineering Systems Advanced Research

    1996-06-01

    The authors present a class of efficient algorithms for PAC learning continuous functions and regressions that are approximated by feedforward networks. The algorithms are applicable to networks with unknown weights located only in the output layer and are obtained by utilizing the potential function methods of Aizerman et al. Conditions relating the sample sizes to the error bounds are derived using martingale-type inequalities. For concreteness, the discussion is presented in terms of neural networks, but the results are applicable to general feedforward networks, in particular to wavelet networks. The algorithms can be directly adapted to concept learning problems.

  18. Enhancement of resident education in sonography using high-speed PACS/ATM image transmission: work in progress

    Science.gov (United States)

    Duerinckx, Andre J.; Grant, Edward G.; Melany, Michelle; Narin, Sherelle L.; Hayrapetian, Alek S.; Valentino, Daniel J.

    1996-05-01

    Transmission of high quality images between hospitals would be of value by exposing residents at individual institutions to a greater mix of disease processes. This problem is particularly serious in ultrasound where individual hospitals may not perform the entire range of examinations. We undertook this study to assess the effectiveness of image transmission via a PACS/ATM global network in improving ultrasound education among residents at affiliated hospitals. Image management was performed by AGFA PACS; global network was Asynchronous Transfer Mode. Selected cases from the two hospitals (OB/GYN cases at one, vascular at the other) were transmitted. Readout/teaching sessions included cases performed at base hospital and those received via network. Evaluation forms were collected from participants at both institutions. No image degradation occurred with transmission. Residents' exposure to ultrasound cases increased at the two hospitals. The system was considered an excellent teaching tool by all faculty and residents surveyed.

  19. Money, politics, and medicine: the American Medical PAC's strategy of giving in U.S. house races.

    Science.gov (United States)

    Wilkerson, J D; Carrell, D

    1999-04-01

    We examine contributions by the American Medical Association's political action committee (AMPAC) to candidates for seats in the U.S. House of Representatives during two electoral cycles (1989-1990 and 1991-1992). In contrast to earlier studies, we do not find any systematic evidence to support the conventional wisdom that AMPAC contributes to influence legislators' positions on roll call votes or that AMPAC's contribution decisions are influenced by legislators' voting positions. We do find that AMPAC contributes to promote access to decision makers and to help elect (or reelect) legislators who would be expected to be more generally sympathetic to the economic and practice concerns of AMA physicians. As points of comparison, we also examine contributions from the top five tobacco PACs and the National Rifle Association's (NRA) PAC and find that legislators' roll call voting positions are strongly related to contributions received from these organizations.

  20. Research on a Valuation Standard and the Actual Condition About Security Management in PACS

    International Nuclear Information System (INIS)

    Jeong, Jae Ho; Son, Gi Gyeong; Kang, Hee Doo; Dong, Kyung Rae; Kweon, Dae Cheol; Kim, Hyun Soo

    2008-01-01

    This study is to prepare an evaluation standard about personal information protection and security management of a medical institution and to build up a grade standard of evaluation in PACS environment. We built up evaluation index based on 10 detailed items in four big categories (political security, technical security, data management security and physical security) by referring to ISO17799 (BS 7799), HIPPA (Health Insurance and Portability and Accountability Act of 1996) and domestic medical law. We have investigated at the thirty places where medical facility with the extracted security criteria and security evaluation index. Average score of physical security list, one of the big categories, was 18.5/20 (93%) at all medical institutions. Political security score was 18.5/30 (62%), data management security score was 12/20 (60%) and technical security score was 17.5/30 (58%). Therefore, security evaluation score was average 67 in 30 general hospitals, which was 4th level. The results showed that it is necessary to establish evaluation and management standard about personal information protection and security consciousness which are weak in PACS environment.

  1. Single- versus Multiobjective Optimization for Evolution of Neural Controllers in Ms. Pac-Man

    Directory of Open Access Journals (Sweden)

    Tse Guan Tan

    2013-01-01

    Full Text Available The objective of this study is to focus on the automatic generation of game artificial intelligence (AI controllers for Ms. Pac-Man agent by using artificial neural network (ANN and multiobjective artificial evolution. The Pareto Archived Evolution Strategy (PAES is used to generate a Pareto optimal set of ANNs that optimize the conflicting objectives of maximizing Ms. Pac-Man scores (screen-capture mode and minimizing neural network complexity. This proposed algorithm is called Pareto Archived Evolution Strategy Neural Network or PAESNet. Three different architectures of PAESNet were investigated, namely, PAESNet with fixed number of hidden neurons (PAESNet_F, PAESNet with varied number of hidden neurons (PAESNet_V, and the PAESNet with multiobjective techniques (PAESNet_M. A comparison between the single- versus multiobjective optimization is conducted in both training and testing processes. In general, therefore, it seems that PAESNet_F yielded better results in training phase. But the PAESNet_M successfully reduces the runtime operation and complexity of ANN by minimizing the number of hidden neurons needed in hidden layer and also it provides better generalization capability for controlling the game agent in a nondeterministic and dynamic environment.

  2. Perturbed-angular-correlation study of the electric-field gradient in {sup 181}Hf-doped and implanted indium sesquioxide

    Energy Technology Data Exchange (ETDEWEB)

    Renteria, M.; Requejo, F.G.; Bibiloni, A.G.; Pasquevich, A.F.; Shitu, J. [Departamento de Fisica, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, CC N67, 1900 La Plata (Argentina); Freitag, K. [Institut fuer Strahlen- und Kernphysik der Universitaet Bonn, Nussallee 14-16, 5300 Bonn (Germany)

    1997-06-01

    We studied the hyperfine interactions of {sup 181}Ta in In{sub 2}O{sub 3} by means of perturbed-angular-correlation (PAC) measurements. We prepared thin films of indium sesquioxide with different degrees of initial amorphism and implanted them with {sup 181}Hf. Chemically prepared indium-sesquioxide powder samples were also made starting from neutron-irradiated HfCl{sub 4}, which provides the {sup 181}Hf PAC probes. PAC experiments were performed on each sample at room temperature, after each step of annealing programs at increasing temperatures up to the full crystallization of the samples. The results indicate that the PAC probe occupies preferentially the axially symmetric cation site. Point-charge-model calculations were performed. The calculated asymmetry parameters {eta} were compared with those obtained in {sup 181}Hf PAC experiments performed also on other binary oxides, showing that the symmetry of the electric-field-gradient (EFG) tensor at {sup 181}Ta cation sites in binary oxides is mainly determined by the nearest-neighbor oxygen-ion distribution around the probe. Comparisons of the experimental results in bixbyites obtained for both PAC probes, {sup 111}Cd and {sup 181}Ta, show that the local EFG in bixbyites, are strongly dependent on the geometry of the sites and the electronic configuration of the probes. {copyright} {ital 1997} {ital The American Physical Society}

  3. Pharmacological studies on drug dependence in rodents: dependence on opioids and CNS depressants.

    Science.gov (United States)

    Suzuki, T

    1990-01-01

    Physical and psychic dependence on opioids and CNS depressants in rodents were examined using the drug-admixed food (DAF) method. A comparison of several methods for developing physical dependence on opioids was made. The DAF method has the advantage of rapidly inducing a high degree of physical dependence without causing morbidity or mortality. When morphine-dependent rats were pretreated with several opioids, naloxone-precipitated weight loss was suppressed in a dose-dependent manner. A procedure for the development of severe physical dependence on CNS depressants was also established. Drug concentrations were rapidly increased until animals showed moderate to severe CNS depression, and then this condition was maintained for at least 10 days. With this procedure, animals became severely dependent on CNS depressants. Another technique, intermittent infusion, was developed that has been used to quantify short-acting CNS depressant dependence potential. The sedative effects of pentobarbital were used as an index in the determination of the injection intervals. These results suggest that the DAF method and the new approaches are useful tools for assessing the physical dependence potential of new drugs. Moreover, oral self-administration and weight pulling procedures were utilized along with the DAF method. Procedures for the oral self-administration of opioids and CNS depressants were established. Opioid-dependent rats pulled the weight to obtain the DAF even though they had free access to normal food. This weight-pulling procedure may be useful for assessing the degree of reinforcing effects for drugs in rats.

  4. Is there a relationship between Internet dependence and eating disorders? A comparison study of Internet dependents and non-Internet dependents.

    Science.gov (United States)

    Tao, Z L; Liu, Y

    2009-01-01

    Several studies have examined the underlying psychopathology in overuse of the Internet, including depression, social anxiety, and substance dependence. A relationship between these psychological disorders appears to exist. No links have been established between Internet dependence and eating disorders. Fifty-four Internet dependents were compared with a control group concerning symptomatic aspects of eating disorders and psychological characteristics related to eating disorders. They all belonged to 1199 respondents of Chinese secondary school and college students between the ages of 12 and 25 years old. A Mann-Whitney U-test was used to determine the difference between Internet dependent groups and non-Internet dependent groups concerning Eating Attitudes Test and Eating Disorder Inventory scores. Females and male Internet dependents rated themselves with significantly higher symptomatic aspects of eating disorders than control groups. Female and male Internet dependents showed significantly higher psychological characteristics related to eating disorders than control groups. A relationship between Internet dependence and eating disorders appears to exist.

  5. Photo-dynamics of the BLUF domain containing soluble adenylate cyclase (nPAC) from the amoeboflagellate Naegleria gruberi NEG-M strain

    Energy Technology Data Exchange (ETDEWEB)

    Penzkofer, A., E-mail: alfons.penzkofer@physik.uni-regensburg.de [Fakultaet fuer Physik, Universitaet Regensburg, Universitaetsstrasse 31, D-93053 Regensburg (Germany); Stierl, M.; Hegemann, P. [Institut fuer Biologie/Experimentelle Biophysik, Humboldt Universitaet zu Berlin, Invalidenstrasse 42, D-10115 Berlin (Germany); Kateriya, Suneel [Department of Biochemistry, University of Delhi South Campus, Benito Juarez Road, New Delhi 110021 (India)

    2011-08-25

    Graphical abstract: The photoactivated adenylyl cyclase (nPAC) from Naegleria gruberi was expressed heterologously in Escherichia coli and its photo-cycling dynamics was studied by optical absorption and fluorescence spectroscopy. Highlights: {yields} Photo-activated adenylyl cyclase (nPAC) from Naegleria gruberi NEG-M was expressed. {yields} Photodynamics of BLUF domain in BLUF sensor - cyclase actuator protein was studied. {yields} Photo-excitation caused BLUF photo-cycling and permanent protein re-conformation. {yields} Re-conformed protein enabled photo-induced flavin reduction by proton transfer. {yields} Fluorescence of flavin in dark- and light-adapted state of nPAC was characterized. - Abstract: The amoeboflagellate Naegleria gruberi NEG-M comprises a BLUF (blue light sensor using flavin) regulated adenylate cyclase (nPAC). The nPAC gene was expressed heterologously in Escherichia coli and the photo-dynamics of the nPAC protein was studied by optical absorption and fluorescence spectroscopy. Blue-light exposure of nPAC caused a typical BLUF-type photo-cycle behavior (spectral absorption red-shift, fluorescence quenching, absorption and fluorescence recovery in the dark). Additionally, time-delayed reversible photo-induced one-electron reduction of fully oxidized flavin (Fl{sub ox}) to semi-reduced flavin (FlH{sup {center_dot}}) occurred. Furthermore, photo-excitation of FlH{sup {center_dot}} caused irreversible electron transfer to fully reduced anionic flavin (FlH{sup -}). A photo-induced electron transfer from Tyr or Trp to flavin (Tyr{sup {center_dot}+}-Fl{sup {center_dot}-} or Trp{sup {center_dot}+}-Fl{sup {center_dot}-} radical ion-pair formation) is thought to cause H-bond restructuring responsible for BLUF-type photo-cycling and permanent protein re-conformation enabling photo-induced flavin reduction by proton transfer. Some photo-degradation of Fl{sub ox} to lumichrome was observed. A model of the photo-dynamics of nPAC is developed.

  6. Study of structural differences between stoichiometric and congruent lithium niobate

    CERN Document Server

    Kling, A; Correia, J G; Da Silva, M F A; Diéguez, E; Agulló-López, F; Soares, J C

    1996-01-01

    The structural differences between stoichiometric and congruent (lithium deficient) lithium niobate single crystals were studied by RBS- and NRA-channeling as well as perturbed angular correlation (PAC) measurements. The d-PAC111Cd-PAC investigations point out that a second Li site can be detected in congruent material, while only one is present in stoichiometric. Channeling studies of different axes and the comparison of the results with computer simulations corroborated former indications that this additional lattice site can be attributed to the formation of ilmenite type stacking faults. A comparative study of the energy dependence of the dechanneling showed that a remarkable disorder is also present in the Nb sublattice of the congruent crystals and that these defects have a point-like character.

  7. Business Model for the Security of a Large-Scale PACS, Compliance with ISO/27002:2013 Standard.

    Science.gov (United States)

    Gutiérrez-Martínez, Josefina; Núñez-Gaona, Marco Antonio; Aguirre-Meneses, Heriberto

    2015-08-01

    Data security is a critical issue in an organization; a proper information security management (ISM) is an ongoing process that seeks to build and maintain programs, policies, and controls for protecting information. A hospital is one of the most complex organizations, where patient information has not only legal and economic implications but, more importantly, an impact on the patient's health. Imaging studies include medical images, patient identification data, and proprietary information of the study; these data are contained in the storage device of a PACS. This system must preserve the confidentiality, integrity, and availability of patient information. There are techniques such as firewalls, encryption, and data encapsulation that contribute to the protection of information. In addition, the Digital Imaging and Communications in Medicine (DICOM) standard and the requirements of the Health Insurance Portability and Accountability Act (HIPAA) regulations are also used to protect the patient clinical data. However, these techniques are not systematically applied to the picture and archiving and communication system (PACS) in most cases and are not sufficient to ensure the integrity of the images and associated data during transmission. The ISO/IEC 27001:2013 standard has been developed to improve the ISM. Currently, health institutions lack effective ISM processes that enable reliable interorganizational activities. In this paper, we present a business model that accomplishes the controls of ISO/IEC 27002:2013 standard and criteria of security and privacy from DICOM and HIPAA to improve the ISM of a large-scale PACS. The methodology associated with the model can monitor the flow of data in a PACS, facilitating the detection of unauthorized access to images and other abnormal activities.

  8. IMPACS: Integrated nuclear medicine information management and PACS

    International Nuclear Information System (INIS)

    Sgouros, G.; Bigler, R.E.; Zanzonico, P.B.; Tsen, M.S.

    1986-01-01

    The high data transmission rates required for rapid image transfer have kept separate the development of PACS and of patient information management systems (PIMS). The resulting dual system requires separate entry of patient data in the PIMS and also in the PACS. The authors are designing a combined Information Management and Picture Archive and Communication System (IMPACS) for nuclear medicine which should result in substantial cost savings. Each PC is part of a PC-based network on which the PIMS runs. Ethernet image transmission (from each camera to an image processing computer) permits quantitation (up to 512 x 512 x 8 bits), while image review transmission is by video (CATV). On-line archiving is on a (2 GB) optical laser disk. Image review requests occur within the PIMS;images are ''grabbed'' locally using a (512 x 512 x 8 bit) frame grabber. A first-order cost estimate of a currently implementable system (Ethernet links initially replaced by floppy disk) is $77,400 (ImageFile, Sudbury Systems, Inc.) plus $20,000 per image review work station (IBM-AT with frame grabber)

  9. Combined PACS and intranet information system in a University Hospital

    International Nuclear Information System (INIS)

    Heiss, D.; Pfluger, T.; Pfeifer, K.J.; Hahn, K.; Koenig, A.; Endres, S.

    2000-01-01

    Purpose: The Department of Radiology at the University Hospital Innenstadt Munich provides all clinical departments of a large university hospital with several radiology units at different locations. During the last four years all units have been fully digitalized with a stepwise installation of a PACS. The PACS also processes images from the Nuclear Medicine Department. Methods: As image modalities, archive systems and review workstations, we use devices from multiple vendors, which are integrated into a consistent system using the DICOM standard. The hospital has developed its own RIS and an intranet information system, which provides access to all reports and images from radiology for all clinical departments inside the hospital. Additionally, other clinical information such as laboratory results or ECG examinations are available through the system. Results: After one year of operation, the system succeeded in the clinical routine work as the primary source for radiological reports and images as well as for laboratory values. Conclusion: The advantages of digitalization were, besides reduction of film cost, especially optimizations of work flow with access to digital images from every where at any time. (orig.) [de

  10. KIS-RIS-PACS integration: the Marburg approach

    International Nuclear Information System (INIS)

    Klose, K.J.; Schaefer, C.; Kail, S.; Roethke, M.; Zhang, L.

    2005-01-01

    When describing the development of data processing at the Department of Radiology at the Philipps University of Marburg, three phases can be identified covering the areas of patient care, education, and research as well as administrative and organizational aspects. The first phase (1987-1995) was centered on radiology and characterized by the early implementation of the radiology information system (RIS) and installation of a picture archiving and communication system (PACS). The experiences gained during this phase led to intensive discussion on application-oriented information processing. The second phase (1996-2000) describes the changes in the general framework brought by Internet technology and international standards. The course was set for the future of data processing in the hospital setting. The phase ended with implementation of a clinical workplace system (KAS) as the basis for a comprehensive electronic patient record and the switch in radiology to an integrated RIS solution. The third phase (2001-2006) addressed further implementation and development of clinical data management in which both regular documentation of patient data and information processing not related to patients are optimized by making use of Intranet/Internet technology. It includes the hospital wide implementation of PACS and the forthcoming phase of information processing increasingly shaped by workflow and decision support. (orig.) [de

  11. Studying the Complex Expression Dependences between Sets of Coexpressed Genes

    Directory of Open Access Journals (Sweden)

    Mario Huerta

    2014-01-01

    Full Text Available Organisms simplify the orchestration of gene expression by coregulating genes whose products function together in the cell. The use of clustering methods to obtain sets of coexpressed genes from expression arrays is very common; nevertheless there are no appropriate tools to study the expression networks among these sets of coexpressed genes. The aim of the developed tools is to allow studying the complex expression dependences that exist between sets of coexpressed genes. For this purpose, we start detecting the nonlinear expression relationships between pairs of genes, plus the coexpressed genes. Next, we form networks among sets of coexpressed genes that maintain nonlinear expression dependences between all of them. The expression relationship between the sets of coexpressed genes is defined by the expression relationship between the skeletons of these sets, where this skeleton represents the coexpressed genes with a well-defined nonlinear expression relationship with the skeleton of the other sets. As a result, we can study the nonlinear expression relationships between a target gene and other sets of coexpressed genes, or start the study from the skeleton of the sets, to study the complex relationships of activation and deactivation between the sets of coexpressed genes that carry out the different cellular processes present in the expression experiments.

  12. Evaluation of PacBio sequencing for full-length bacterial 16S rRNA gene classification.

    Science.gov (United States)

    Wagner, Josef; Coupland, Paul; Browne, Hilary P; Lawley, Trevor D; Francis, Suzanna C; Parkhill, Julian

    2016-11-14

    Currently, bacterial 16S rRNA gene analyses are based on sequencing of individual variable regions of the 16S rRNA gene (Kozich, et al Appl Environ Microbiol 79:5112-5120, 2013).This short read approach can introduce biases. Thus, full-length bacterial 16S rRNA gene sequencing is needed to reduced biases. A new alternative for full-length bacterial 16S rRNA gene sequencing is offered by PacBio single molecule, real-time (SMRT) technology. The aim of our study was to validate PacBio P6 sequencing chemistry using three approaches: 1) sequencing the full-length bacterial 16S rRNA gene from a single bacterial species Staphylococcus aureus to analyze error modes and to optimize the bioinformatics pipeline; 2) sequencing the full-length bacterial 16S rRNA gene from a pool of 50 different bacterial colonies from human stool samples to compare with full-length bacterial 16S rRNA capillary sequence; and 3) sequencing the full-length bacterial 16S rRNA genes from 11 vaginal microbiome samples and compare with in silico selected bacterial 16S rRNA V1V2 gene region and with bacterial 16S rRNA V1V2 gene regions sequenced using the Illumina MiSeq. Our optimized bioinformatics pipeline for PacBio sequence analysis was able to achieve an error rate of 0.007% on the Staphylococcus aureus full-length 16S rRNA gene. Capillary sequencing of the full-length bacterial 16S rRNA gene from the pool of 50 colonies from stool identified 40 bacterial species of which up to 80% could be identified by PacBio full-length bacterial 16S rRNA gene sequencing. Analysis of the human vaginal microbiome using the bacterial 16S rRNA V1V2 gene region on MiSeq generated 129 operational taxonomic units (OTUs) from which 70 species could be identified. For the PacBio, 36,000 sequences from over 58,000 raw reads could be assigned to a barcode, and the in silico selected bacterial 16S rRNA V1V2 gene region generated 154 OTUs grouped into 63 species, of which 62% were shared with the MiSeq dataset. The Pac

  13. Application of PAC and flocculants for improving settling of solid particles in oilfield wastewater with high salinity and Ca2.

    Science.gov (United States)

    Liu, Guoliang; Zhang, Fusheng; Qu, Yuanzhi; Liu, He; Zhao, Lun; Cui, Mingyue; Ou, Yangjian; Geng, Dongshi

    2017-09-01

    The suspended solids in wastewater from Rekabak oilfield, Kazakhstan, were characterized and treated with flocculants to enhance settling. The wastewater contained a high concentration of total dissolved solids and calcium ion. Scanning electron microscopy and energy dispersive X-ray analyses showed that suspended solids were mainly composed of corrosion products (iron oxides) and silicon dioxide particles. Also, much salt deposition from wastewater caused a large increase in the suspended solids value. The settling of solid particles in wastewater was investigated by turbidity decrease within 60 min. The particle settling was enhanced by adding polyaluminum chloride (PAC) as coagulant and hydrolyzed polyacryamide (HPAM) or cationic polyacrylamide (CPAM) as flocculant. At optimal dose, the particle settling ability with PAC and CPAM was better than that with PAC and HPAM. Particle size analysis showed that HPAM or CPAM with high molecular weight played an important role for enlarging the particle size. The experiments with simulated wastewater showed that particle settling by using HPAM deteriorated significantly compared to that by CPAM at high calcium ion. This study provides further understanding about the effect of high salinity and Ca 2+ on solids formation, flocculant performance and particle settling. Meanwhile, the results are also helpful to develop novel flocculants used for high salinity wastewater.

  14. Temperature dependent conformation studies of Calmodulin Protein using Molecular Dynamics

    Science.gov (United States)

    Aneja, Sahil; Bhartiya, Vivek Kumar; Negi, Sunita

    2016-10-01

    Calmodulin (CaM) protein plays a very crucial role in the calcium signaling inside the eukaryotic cell structure [1, 2]. It can also bind to other proteins/targets and facilitate various activities inside the cell [3, 4]. Temperature dependent conformation changes in the CaM protein are studied with extensive molecular dynamics simulations. The quantitative comparison of simulation data with various forms of experimental results probing different aspects of the folding process can facilitate robust assessment of the accuracy of the calculations. It can also provide a detailed structural interpretation for the experimental observations as well as physical interpretation for theory behind different aspects of the experiment. Earlier these kinds of studies have been performed experimentally using fluorescence measurements as in [5]. The calcium bound form of CaM is observed to undergo a reversible conformation change in the range 295-301 K at calcium ion concentration 150 mM. The transition temperature was observed to depend on the calcium ion concentration of the protein. Leap-dynamics approach was used earlier to study the temperature dependent conformation change of CaM [6]. At 290 K, both the N- and C-lobes were stable, at 325 K, the C-lobe unfolds whereas at 360 both the lobes unfold [6]. In this work, we perform molecular dynamics simulations of 100 ns each for the temperatures 325 K and 375 K on the apo form of CaM, 3CLN and 1CFD. A remarkable dependence of the temperature is observed on the overall dynamics of both the forms of the protein as reported in our earlier study [7, 8]. 1CFD shows a much flexible linker as compared to 3CLN whereas the overall dynamics of the lobes mainly N-lobe is observed to be more in later case. Salt bridge formation between the residues 2 (ASP) and 148 (LYS) leads to a more compact form of 1CFD at 325 K. The unfolding of the protein is observed to increase with the increase in the temperature similar to the earlier reported

  15. Implementation and Validation of PACS Integrated Peer Review for Discrepancy Recording of Radiology Reporting

    NARCIS (Netherlands)

    Olthof, A. W.; van Ooijen, P. M. A.

    The purpose of this work is to demonstrate the possibility of implementation of a PACS-integrated peer review system based on RADPEER T classification providing a step-wise implementation plan utilizing features already present in the standard PACS implementation and without the requirement of

  16. Structural study of surfactant-dependent interaction with protein

    Energy Technology Data Exchange (ETDEWEB)

    Mehan, Sumit; Aswal, Vinod K., E-mail: vkaswal@barc.gov.in [Solid State Physics Division, Bhabha Atomic Research Centre, Mumbai 400 085 (India); Kohlbrecher, Joachim [Laboratory for Neutron Scattering, Paul Scherrer Institut, CH-5232 PSI Villigen (Switzerland)

    2015-06-24

    Small-angle neutron scattering (SANS) has been used to study the complex structure of anionic BSA protein with three different (cationic DTAB, anionic SDS and non-ionic C12E10) surfactants. These systems form very different surfactant-dependent complexes. We show that the structure of protein-surfactant complex is initiated by the site-specific electrostatic interaction between the components, followed by the hydrophobic interaction at high surfactant concentrations. It is also found that hydrophobic interaction is preferred over the electrostatic interaction in deciding the resultant structure of protein-surfactant complexes.

  17. Study of heavy quarkonium with energy dependent potential

    International Nuclear Information System (INIS)

    Gupta, Pramila; Mehrotra, I

    2009-01-01

    It is well known that charmonium and bottonium states can be calculated by using a nonrelativistic Schrodinger equation. The basic reasons are: 1) the mass of charm and bottom quarks is much larger than QCD scale, which makes this system free of strong normalization effects and 2) the binding energy is small compared to the mass energy ψ and γ states in terms of nonrelativistic qq system governed by more or less phenomenological potentials. In the present work we have studied mass spectra of charmonium and bottonium using the following energy dependent model in the framework of nonrelativistic Schrodinger equation

  18. Scalable ultrasound PACS: evolving needs for multimode ultrasound image and data management

    Science.gov (United States)

    Gustafson, David E.; Klepper, John R.; Choi, Hyung-Sik; Kim, Yongmin

    1994-05-01

    We propose a scalable approach to ultrasound PACS. The general lack of any network interface capability on a large percentage of installed ultrasound scanners limits the solution available in the near term. A staged implementation beginning with a small number of ultrasound scanners interfaced to a single networked acquisition station is proposed. Initial mini-PACS may provide better utilization of the shared resources, such as archive and print servers and imagers, which would be cost prohibitive in a one-machine-per-scanner configuration. As the system requirements grow and ultrasound systems add direct network support, mini-PACS performances can overcome the initial single acquisition node bottleneck encountered with video-capture based systems, and ultrasound PACS can be integrated into a full hospital-wide PACS.

  19. Reliability of the Norwegian Version of the Children's Assessment of Participation and Enjoyment (CAPE) and Preferences for Activities of Children (PAC)

    Science.gov (United States)

    Nordtorp, Heidi L.; Nyquist, Astrid; Jahnsen, Reidun; Moser, Thomas; Strand, Liv Inger

    2013-01-01

    This study examined test-retest reliability of the Norwegian version of Children's Assessment of Participation and Enjoyment (CAPE), and Preferences for Activities of Children (PAC) in children with and without disabilities. Totally 141 children, 107 typically developing, mean age 11.1, and 34 with disabilities, mean age 14.2 years participated. A…

  20. DICOM-compliant PACS with CD-based image archival

    Science.gov (United States)

    Cox, Robert D.; Henri, Christopher J.; Rubin, Richard K.; Bret, Patrice M.

    1998-07-01

    This paper describes the design and implementation of a low- cost PACS conforming to the DICOM 3.0 standard. The goal was to provide an efficient image archival and management solution on a heterogeneous hospital network as a basis for filmless radiology. The system follows a distributed, client/server model and was implemented at a fraction of the cost of a commercial PACS. It provides reliable archiving on recordable CD and allows access to digital images throughout the hospital and on the Internet. Dedicated servers have been designed for short-term storage, CD-based archival, data retrieval and remote data access or teleradiology. The short-term storage devices provide DICOM storage and query/retrieve services to scanners and workstations and approximately twelve weeks of 'on-line' image data. The CD-based archival and data retrieval processes are fully automated with the exception of CD loading and unloading. The system employs lossless compression on both short- and long-term storage devices. All servers communicate via the DICOM protocol in conjunction with both local and 'master' SQL-patient databases. Records are transferred from the local to the master database independently, ensuring that storage devices will still function if the master database server cannot be reached. The system features rules-based work-flow management and WWW servers to provide multi-platform remote data access. The WWW server system is distributed on the storage, retrieval and teleradiology servers allowing viewing of locally stored image data directly in a WWW browser without the need for data transfer to a central WWW server. An independent system monitors disk usage, processes, network and CPU load on each server and reports errors to the image management team via email. The PACS was implemented using a combination of off-the-shelf hardware, freely available software and applications developed in-house. The system has enabled filmless operation in CT, MR and ultrasound within

  1. A control study on treatment for benzodiazepine dependence with trazodone

    Directory of Open Access Journals (Sweden)

    ZHANG Hong-ju

    2013-05-01

    Full Text Available Objective To determine the efficacy and safety of trazodone in the treatment of benzodiazepine dependence. Methods Forty insomnia patients who met the Classification and Diagnostic Criteria of Mental Disorders in China Third Edition (CCMD-3 of dependence syndrome due to benzodiazepine were involved in the study. Patients were randomly assigned to trazodone group and placebo group for 3 months. The efficacy were assessed by Withdrawal Symptoms Checklist, Hamilton Anxiety Rating Scale (HAMA and polysomnography (PSG. Adverse events were assessed by Treatment Emergent Symptom Scale (TESS. Results The Withdrawal Symptoms Checklist of trazodone group was significantly lower after 7 d treatment than that of placebo group (P = 0.000, and HAMA score of the trazodone group was also significantly lower after 15 d treatment than that of placebo group (P = 0.000. There were no difference in Withdrawal Symptoms Checklist and HAMA of placebo group before and after treatment. Withdrawal Symptoms Checklist and HAMA of the trazodone group were decreased after treatment (P = 0.000. In comparison with placebo group, sleep parameters of the trazodone, including total sleep time (TST, sleep efficiency (SE, sleep latency (SL and slow wave sleep (SWS time presented improvement after 7 d treatment (P = 0.000, for all. After trazodone treatment, total sleep time, slow wave sleep time, sleep efficiency and sleep latency were improved (P = 0.000, for all. No obvious adverse reaction occurred. There were no significant differences in TESS scores between pre? and post?treatment in both groups (P > 0.05. Conclusion Trazodone is markedly effective and safe in the treatment for benzodiazepine dependence.

  2. The cranberry flavonoids PAC DP-9 and quercetin aglycone induce cytotoxicity and cell cycle arrest and increase cisplatin sensitivity in ovarian cancer cells

    Science.gov (United States)

    WANG, YIFEI; HAN, ALEX; CHEN, EVA; SINGH, RAKESH K.; CHICHESTER, CLINTON O.; MOORE, RICHARD G.; SINGH, AJAY P.; VORSA, NICHOLI

    2015-01-01

    Cranberry flavonoids (flavonols and flavan-3-ols), in addition to their antioxidant properties, have been shown to possess potential in vitro activity against several cancers. However, the difficulty of isolating cranberry compounds has largely limited anticancer research to crude fractions without well-defined compound composition. In this study, individual cranberry flavonoids were isolated to the highest purity achieved so far using gravity and high performance column chromatography and LC-MS characterization. MTS assay indicated differential cell viability reduction of SKOV-3 and OVCAR-8 ovarian cancer cells treated with individual cranberry flavonoids. Treatment with quercetin aglycone and PAC DP-9, which exhibited the strongest activity, induced apoptosis, led to caspase-3 activation and PARP deactivation, and increased sensitivity to cisplatin. Furthermore, immunofluorescence microscopy and western blot study revealed reduced expression and activation of epidermal growth factor receptor (EGFR) in PAC DP-9 treated SKOV-3 cells. In addition, quercetin aglycone and PAC DP-9 deactivated MAPK-ERK pathway, induced downregulation of cyclin D1, DNA-PK, phosphohistone H3 and upregulation of p21, and arrested cell cycle progression. Overall, this study demonstrates promising in vitro cytotoxic and anti-proliferative properties of two newly characterized cranberry flavonoids, quercetin aglycone and PAC DP-9, against ovarian cancer cells. PMID:25776829

  3. Scale dependence of acoustic velocities. An experimental study

    Energy Technology Data Exchange (ETDEWEB)

    Gotusso, Angelamaria Pillitteri

    2001-06-01

    Reservoir and overburden data (e.g. seismic, sonic log and core data) are collected at different stages of field development, at different scales, and under different measurement conditions. A more precise reservoir characterization could be obtained by combining all the collected data. Reliable data may also be obtained from drill cuttings. This methodology can give data in quasi-real time, it is easily applicable, and cheap. It is then important, to understand the relationship between results obtained from measurements at different scales. In this Thesis acoustic velocities measured at several different laboratory scales are presented. This experimental study was made in order to give the base for the development of a model aiming to use/combine appropriately the data collected at different scales. The two main aspects analyzed are the experimental limitations due to the decrease in sample size and the significance of measurements in relation to material heterogeneities. Plexiglas, an isotropic, non-dispersive artificial material, with no expected scale effect, was used to evaluate the robustness of the measurement techniques. The results emphasize the importance of the wavelength used with respect to the sample length. If the sample length (L) is at least 5 time bigger than wavelength used ({lambda}), then the measured velocities do not depend on sample size. Leca stone, an artificial isotropic material containing spherical grains was used to evaluate the combined effects of technique, heterogeneities and sample length. The ratio between the scale of the heterogeneities and the sample length has to be taken in to account. In this case velocities increase with decreasing sample length when the ratio L/{lambda} is smaller than 10-15 and at the same time the ratio between sample length and grain size is greater than 10. Measurements on natural rocks demonstrate additional influence of grain mineralogy, shape and orientation. Firenzuola sandstone shows scale and

  4. Workstation and network needs for very large PACS implementations

    Science.gov (United States)

    Hayrapetian, Alek S.; Duerinckx, Andre J.; Harmon, Craig; Kenagy, John J.; Grant, Edward G.

    1997-05-01

    Large hospitals require many viewing stations for image access by referring doctors and personnel from the operating rooms and emergency room. We propose to discuss our experience in providing such review stations with inexpensive PC-based workstations, fast switched Ethernet and a client-server architecture within a large hospital. The bulk of computing processes overhead such as data acquisition, formatting, archiving, database management, routing was performed by large servers and 2 Ethernet giga- switches which are part of our PACS. PC-based workstations performed data retrieval and display functions with user configurable software. Ultrasound, MRI, CT, Angiography and digitized x-ray images were available on the servers. Referring doctors in ICU, CCU were very receptive to this technology. Film use decreased somewhat for hose services using this new technology. PC-based workstations can provide an economically viable solution for image data access by referring physicians and other staff.

  5. Teleradiology and PACS - strategy of the Innsbruck University Hospital

    International Nuclear Information System (INIS)

    Vogl, R.

    2005-01-01

    Systems for management of digital imaging data are very important and widespread at the Innsbruck University Hospital and constitute a central component of the IT strategies followed by the hospital operating company TILAK (Tyrolean public hospitals). The particular goal is to integrate all imaging data into the electronic medical records and make these available online to each of the approx. 2500 clinic workstations and ensure electronic data exchange with other healthcare services. Teleradiology connections have been established at the University Clinic for Radiology since 1995; these have been continually expanded and linked to the central PACS. An eHealth web portal was recently established to facilitate transfer of images and findings from TILAK hospitals to other healthcare organizations. Registered users can be cleared for a limited time to access all radiological imaging data via this web portal. (orig.) [de

  6. Proceedings of the 22nd Particle Accelerator Conference (PAC'07)

    International Nuclear Information System (INIS)

    2007-01-01

    The twenty-second Particle Accelerator Conference, PAC'07, took place at the Albuquerque Convention Centre in Albuquerque, the largest city in New Mexico, from Monday to Friday, 2007 June 25 to 29. It was attended by over 1350 delegates from 25 different countries (63% North America, 24% Europe, 11% Asia and 2% Other), and was held under the auspices of the two professional societies that oversee and make holding this series of conferences possible, the Division of Physics of Beams within APS, and the Nuclear and Plasma Sciences Society within IEEE. As host of the conference, Los Alamos National Laboratory (LANL) is especially thanked for their many contributions and assistance both prior to and during the conference. The Convention Center was an ideal location for information sharing and discussions between the interdisciplinary aspects of the accelerator community, as well as for related meetings and ad-hoc 'rump' sessions.

  7. Report on the 2005 Particle Accelerator Conference (PAC05)

    International Nuclear Information System (INIS)

    Kathy F. Rosenbalm

    2005-01-01

    The 21st Particle Accelerator Conference, PAC05, took place at the Knoxville Convention Center (KCC) from Monday through Friday, May 16-20, 2005. Sponsored by the American Physical Society (APS), the Institute of Electrics and Electronics Engineers (IEEE) with its subdivision of Nuclear and Plasma Sciences Society (NPSS), the conference was hosted by the Oak Ridge National Laboratory (ORNL) Spallation Neutron Source (SNS) Project and Thomas Jefferson National Accelerator Facility (JLab). The conference was chaired by Norbert Holtkamp, and the Local Organizing Committee was made up of staff from the ORNL SNS Project under the chairmanship of Stuart Henderson. The conference welcomed over 1400 delegates from the United States, Europe, Asia, the Middle East, South America and from as far away as Australia. Almost 1400 papers where processed during the conference and will be published on the Joint Accelerator Conferences Website (JACoW) page

  8. Building and using a PACS in pathology and cytology

    Science.gov (United States)

    van Drunen, Rudi; van Teylingen, Geert; Boon, Mathilde E.; Kok, Lambrecht P.

    2001-08-01

    Applications of Picture Archiving and Communication Systems (PACS) in Pathology and Cytology are currently hardly used in the diagnostic process. Here we describe a system that, together with existing equipment, stores data from cervix smears, and aids the physician in the diagnostic process. The system comprises of a scanning system for the specimen and a multi-level storage system partly on disk and partly on optical media. The system adds additional benefits in the diagnostic process while at the same time provides a safe long-term storage and archive of the data. Due to the open nature and the cost-effectiveness of this solution applications of this system can be found not only in cervical cytology but also in pathology or other parts of medicine where image processing or storage is a major issue.

  9. Longitudinal Studies of Angiogenesis in Hormone-Dependent Shionogi Tumors

    Directory of Open Access Journals (Sweden)

    Trevor P. Wade

    2007-07-01

    Full Text Available Vessel size imaging was used to assess changes in the average vessel size of Shionogi tumors throughout the tumor growth cycle. Changes in R2 and R2* relaxivities caused by the injection of a superparamagnetic contrast agent (ferumoxtran-10 were measured using a 2.35-T animal magnetic resonance imaging system, and average vessel size index (VSI was calculated for each stage of tumor progression: growth, regression, and relapse. Statistical analysis using Spearman rank correlation test showed no dependence between vessel size and tumor volume at any stage of the tumor growth cycle. Paired Student's t test was used to assess the statistical significance of the differences in average vessel size for the three stages of the tumor growth cycle. The average VSI for regressing tumors (15.1 ± 6.6 wm was significantly lower than that for growing tumors (35.2 ± 25.5 μm; P < .01. Relapsing tumors also had an average VSI (45.4 ± 41.8 μm higher than that of regressing tumors, although the difference was not statistically significant (P = .067. This study shows that VSI imaging is a viable method for the noninvasive monitoring of angiogenesis during the progression of a Shionogi tumor from androgen dependence to androgen independence.

  10. A neurosurgery/stereotactic radiotherapy dedicated PACS for conformal radiotherapy

    International Nuclear Information System (INIS)

    Lefkopoulos, D.; Bocquiault, P.; Levrier, M.; Merienne, L.; Schlienger, M.

    1995-01-01

    To realise conformal cerebral stereotactic irradiations we use a Neurosurgery/stereotactic dedicated PACS between two distant hospitals. It connects the stereotactic neurosurgery planification imaging system NEUROAXIS (Sopelem-Sofretec/Ste Anne Hospital) with the dosimetric TPS ARTEMIS-3D/Dosigray (Tenon Hospital). NEUROAXIS is a computer aided stereotactic biopsies and stereo-electroencephalographies, used by surgeons in operating room. The system determines the precise location data for Talairach radiological equipment (X ray source at 5 meters from film) and the geometry of scanner and MRI stereotactical referentials. It provides a full set of features for lesion localization, geometrical computations, surgical planifications, picture archiving, stereotactic angiography, CT and MRI image processing and networking. It sends images through the French public digital network ISDN (NUMERIS/France Telecom : 2x64 Kbits/s) from Ste Anne to Tenon Hospital. Stereotactic angiographic and CT images are reformatted into the DOSIGRAY image processing environment where 3-D dose distributions, displays and DVHs are computed to determine the optimal treatment. ARTEMIS-3D/Dosigray is a TPS for stereotactic radiotherapy devised by the Tenon Hospital for clinical methodology and 3D dose calculations, optimization software development and the Dosigray company for multimodality imaging, (2D(3D)) computer graphics for dose and anatomical representation and data networking. Communication within the radiation oncology department is provided by local area ETHERNET network, linking heterogeneous systems (Vaxstations-3200; Decstation (5000(240))) by means of different protocols. The works in progress are to send back via the same network the 3-D dose matrix to Neurosurgery department NEUROAXIS system. Our PACS is used since six months to treat patients. It has permitted to improve the treatment quality in comparison with our first version TPS ARTEMIS-3D

  11. [Impact of a PACS/RIS-integrated speech recognition system on radiology reporting time and report availability].

    Science.gov (United States)

    Trumm, C G; Glaser, C; Paasche, V; Crispin, A; Popp, P; Küttner, B; Francke, M; Nissen-Meyer, S; Reiser, M

    2006-04-01

    Quantification of the impact of a PACS/RIS-integrated speech recognition system (SRS) on the time expenditure for radiology reporting and on hospital-wide report availability (RA) in a university institution. In a prospective pilot study, the following parameters were assessed for 669 radiographic examinations (CR): 1. time requirement per report dictation (TED: dictation time (s)/number of images [examination] x number of words [report]) with either a combination of PACS/tape-based dictation (TD: analog dictation device/mini-cassette/transcription) or PACS/RIS/speech recognition system (RR: remote recognition/transcription and OR: online recognition/self-correction by radiologist), respectively, and 2. the Report Turnaround Time (RTT) as the time interval from the entry of the first image into the PACS to the available RIS/HIS report. Two equal time periods were chosen retrospectively from the RIS database: 11/2002 - 2/2003 (only TD) and 11/2003 - 2/2004 (only RR or OR with speech recognition system [SRS]). The mid-term (> or = 24 h, 24 h intervals) and short-term (reports during the 1st to 24th hour) were calculated. Prospectively, there was a significant difference between TD/RR/OR (n = 151/257/261) regarding mean TED (0.44/0.54/0.62 s [per word and image]) and mean RTT (10.47/6.65/1.27 h), respectively. Retrospectively, 37 898/39 680 reports were computed from the RIS database for the time periods of 11/2002 - 2/2003 and 11/2003 - 2/2004. For CR/CT there was a shift of the short-term RA to the first 6 hours after examination completion (mean cumulative RA 20 % higher) with a more than three-fold increase in the total number of available reports within 24 hours (all modalities). The RIMRA for CR/CT/MR was 3.1/5.8/4.0 in the first 24 hours, and 2.0 for XA/DS in the second 24-hour interval. In comparison to tape-based dictation, an SRS results in a significantly higher primary time expenditure and a modified report dictation workflow. In a university institution

  12. Study of the strategies and controls of fuel cell systems associated with traction; Etude des strategies et des structures de commande pour le pilotage des systemes energetiques a Pile a Combustible (PAC) destines a la traction

    Energy Technology Data Exchange (ETDEWEB)

    Lachaize, J.

    2004-09-15

    This work falls into project COPPACE (Contribution to the Control of Embedded Fuel cell) carried out by ALSTOM in partnership with the LEEI-INPT and the CEA and supported by the ADEME. The study deals with the modelling and the control of a Fuel Cell system (flow, pressure, temperature) and the definition of the control laws for the static inverters associated with the traction of power train. We develop then a strategy of management of energy by taking into account the criteria of the hydrogen consumption or energy stored in the ultracaps. Each step is verified by total simulation according to a specific profile of mission and a precise model of fuel cells which has been simplified to reduce the computing time. The control of this system is defined by a separate treatment of the components, to finalize the total function objective. The results of simulations show that the system can follow the requested power while controlling the critical elements. (author)

  13. Benefits of Integrated RIS/PACS/Reporting Due to Automatic Population of Templated Reports.

    Science.gov (United States)

    Kovacs, Mark D; Cho, Maximilian Y; Burchett, Philip F; Trambert, Michael

    2018-01-06

    With integration of the Radiological Information Systems (RIS), Picture Archiving and Communication systems (PACS), and reporting systems, patient identifiers and examination information can automatically map into examination reports. There are many potential benefits of report automation to radiologists including improvements in efficiency, accuracy, and fatigue. In this article we describe a 2 part study, with the first part being an anonymous survey of radiologists concerning report automation. A total of 13 staff radiologists and 9 radiology residents at a single institution completed an anonymous survey. Respondents were asked if automatic population of examination description, comparison examination data, indications, computed tomography dose, technique, and copy to physician data saved time, decreased fatigue, and increased accuracy. Respondents were asked if a "copy findings" function saved time. The second objective part of the study was a mock examination experiment to assess time savings of report automation and to assess error rates. Of all, 9 radiologists were asked to dictate fields for 8 mock examinations. Subjects were timed and reporting errors monitored. Estimated daily time savings and error rates were calculated assuming a mix of 80 studies. A total of 95% surveyed responded that report automation saved time; 91% that report automation improved accuracy of dictations; 82% that report automation decreased fatigue. Furthermore, 83% of copy finding function users reported time savings. Average time to dictate these prepopulated fields was 51 seconds per study. Average error rate per report was 0.86, with an average of 0.26 errors remaining uncorrected upon report completion. Estimated average time per day saved per radiologist from report automation was 68 minutes. Estimated average corrected errors was 48 per day. Estimated average uncorrected or missed errors was 21 per day. These estimated benefits from report automation result from tight

  14. Estudio paleoetnobotánico en la Costa Pacífica Vallecaucana

    Directory of Open Access Journals (Sweden)

    Romero Picón Yuri

    1996-06-01

    Full Text Available As part of the INCIVA's Archaeological Research Program in the Valle del Cauca region of the Pacilic coast, this study seeks to contribute, from the anthropological and ecological perspective of paleoethnobotany, elements that will aid in the reconstruction of the nutritional base of the prehispanic populations settled in the alluvial valleys of the San Juan and Calimarivers.Inscrito dentro del Programa de Investigaciones Arqueológicas que adelanta el INCIVA en la Costa Pacífica Vallecaucana, este estudio busca aportar desde un enfoque antropológico y ecológico de la Paleoetnobotánica, elementos que contribuyan a reconstruir la naturaleza de la base alimenticia de las poblaciones prehispánicas asentadas en la llanura aluvial de los ríos Calima y San Juan.

  15. Relating PAC damping to EFG fluctuation rates through the PAC relaxation peak. Dynamic N-state symmetric models

    Science.gov (United States)

    Park, Tyler; Hodges, Jeffery A.; Moreno, Carlos; Stufflebeam, Michael; Evenson, William E.; Matheson, P.; Zacate, M. O.; Collins, Gary S.

    2011-07-01

    A perturbed angular correlation (PAC) experiment that measures dynamic damping also needs information about the fundamental quadrupole frequency to relate the damping as a function of temperature to the EFG fluctuation rate. When the experiment is unable to access slow electric field gradient (EFG) fluctuations that show the fundamental quadrupole frequency directly, one needs additional information to determine the hyperfine field parameters and thereby the connection between observed damping and EFG fluctuation rates. One way to solve this problem is to estimate the hyperfine parameters from the fluctuation rate for maximum damping (i.e. at the relaxation peak) or from the rate of maximum damping. This work relates both the maximum damping rate and the fluctuation rate at the relaxation peak to EFG magnitudes (or quadrupole frequencies) for five dynamic N-state symmetric models of fluctuating EFGs.

  16. Crystal Structure of the PAC1R Extracellular Domain Unifies a Consensus Fold for Hormone Recognition by Class B G-Protein Coupled Receptors

    Energy Technology Data Exchange (ETDEWEB)

    Kumar, Shiva; Pioszak, Augen; Zhang, Chenghai; Swaminathan, Kunchithapadam; Xu, H. Eric (Van Andel); (NU Singapore)

    2012-02-21

    Pituitary adenylate cyclase activating polypeptide (PACAP) is a member of the PACAP/glucagon family of peptide hormones, which controls many physiological functions in the immune, nervous, endocrine, and muscular systems. It activates adenylate cyclase by binding to its receptor, PAC1R, a member of class B G-protein coupled receptors (GPCR). Crystal structures of a number of Class B GPCR extracellular domains (ECD) bound to their respective peptide hormones have revealed a consensus mechanism of hormone binding. However, the mechanism of how PACAP binds to its receptor remains controversial as an NMR structure of the PAC1R ECD/PACAP complex reveals a different topology of the ECD and a distinct mode of ligand recognition. Here we report a 1.9 {angstrom} crystal structure of the PAC1R ECD, which adopts the same fold as commonly observed for other members of Class B GPCR. Binding studies and cell-based assays with alanine-scanned peptides and mutated receptor support a model that PAC1R uses the same conserved fold of Class B GPCR ECD for PACAP binding, thus unifying the consensus mechanism of hormone binding for this family of receptors.

  17. Crystal structure of the PAC1R extracellular domain unifies a consensus fold for hormone recognition by class B G-protein coupled receptors.

    Science.gov (United States)

    Kumar, Shiva; Pioszak, Augen; Zhang, Chenghai; Swaminathan, Kunchithapadam; Xu, H Eric

    2011-01-01

    Pituitary adenylate cyclase activating polypeptide (PACAP) is a member of the PACAP/glucagon family of peptide hormones, which controls many physiological functions in the immune, nervous, endocrine, and muscular systems. It activates adenylate cyclase by binding to its receptor, PAC1R, a member of class B G-protein coupled receptors (GPCR). Crystal structures of a number of Class B GPCR extracellular domains (ECD) bound to their respective peptide hormones have revealed a consensus mechanism of hormone binding. However, the mechanism of how PACAP binds to its receptor remains controversial as an NMR structure of the PAC1R ECD/PACAP complex reveals a different topology of the ECD and a distinct mode of ligand recognition. Here we report a 1.9 Å crystal structure of the PAC1R ECD, which adopts the same fold as commonly observed for other members of Class B GPCR. Binding studies and cell-based assays with alanine-scanned peptides and mutated receptor support a model that PAC1R uses the same conserved fold of Class B GPCR ECD for PACAP binding, thus unifying the consensus mechanism of hormone binding for this family of receptors.

  18. Crystal structure of the PAC1R extracellular domain unifies a consensus fold for hormone recognition by class B G-protein coupled receptors.

    Directory of Open Access Journals (Sweden)

    Shiva Kumar

    Full Text Available Pituitary adenylate cyclase activating polypeptide (PACAP is a member of the PACAP/glucagon family of peptide hormones, which controls many physiological functions in the immune, nervous, endocrine, and muscular systems. It activates adenylate cyclase by binding to its receptor, PAC1R, a member of class B G-protein coupled receptors (GPCR. Crystal structures of a number of Class B GPCR extracellular domains (ECD bound to their respective peptide hormones have revealed a consensus mechanism of hormone binding. However, the mechanism of how PACAP binds to its receptor remains controversial as an NMR structure of the PAC1R ECD/PACAP complex reveals a different topology of the ECD and a distinct mode of ligand recognition. Here we report a 1.9 Å crystal structure of the PAC1R ECD, which adopts the same fold as commonly observed for other members of Class B GPCR. Binding studies and cell-based assays with alanine-scanned peptides and mutated receptor support a model that PAC1R uses the same conserved fold of Class B GPCR ECD for PACAP binding, thus unifying the consensus mechanism of hormone binding for this family of receptors.

  19. Design and implementation of GRID-based PACS in a hospital with multiple imaging departments

    Science.gov (United States)

    Yang, Yuanyuan; Jin, Jin; Sun, Jianyong; Zhang, Jianguo

    2008-03-01

    Usually, there were multiple clinical departments providing imaging-enabled healthcare services in enterprise healthcare environment, such as radiology, oncology, pathology, and cardiology, the picture archiving and communication system (PACS) is now required to support not only radiology-based image display, workflow and data flow management, but also to have more specific expertise imaging processing and management tools for other departments providing imaging-guided diagnosis and therapy, and there were urgent demand to integrate the multiple PACSs together to provide patient-oriented imaging services for enterprise collaborative healthcare. In this paper, we give the design method and implementation strategy of developing grid-based PACS (Grid-PACS) for a hospital with multiple imaging departments or centers. The Grid-PACS functions as a middleware between the traditional PACS archiving servers and workstations or image viewing clients and provide DICOM image communication and WADO services to the end users. The images can be stored in distributed multiple archiving servers, but can be managed with central mode. The grid-based PACS has auto image backup and disaster recovery services and can provide best image retrieval path to the image requesters based on the optimal algorithms. The designed grid-based PACS has been implemented in Shanghai Huadong Hospital and been running for two years smoothly.

  20. Sample holder for studying temperature dependent particle guiding

    International Nuclear Information System (INIS)

    Bereczky, R.J.; Toekesi, K.; Kowarik, G.; Aumayr, F.

    2011-01-01

    Complete text of publication follows. The so called guiding effect is a complex process involving the interplay of a large number of charged particles with a solid. Although many research groups joined this field and carried out various experiments with insulator capillaries many details of the interactions are still unknown. We investigated the temperature dependence of the guiding since it opens new possibilities both for a fundamental understanding of the guiding phenomenon and for applications. For the temperature dependent guiding experiments a completely new heatable sample holder was designed. We developed and built such a heatable sample holder to make accurate and reproducible studies of the temperature dependence of the ion guiding effect possible. The target holder (for an exploded view see Fig. 1) consists of two main parts, the front and the back plates. The two plates of the sample holder, which function as an oven, are made of copper. These parts surround the capillary in order to guarantee a uniform temperature along the whole tube. The temperature of the copper parts is monitored by a K-Type thermocouple. Stainless steel coaxial heaters surrounding the oven are used for heating. The heating power up to a few watts is regulated by a PID controller. Cooling of the capillary is achieved by a copper feed-through connected to a liquid nitrogen bath outside the UHV chamber. This solution allows us to change the temperature of the sample from -30 deg C up to 90 deg C. Our experiments with this newly developed temperature regulated capillary holder show that the glass temperature (i.e. conductivity) can be used to control the guiding properties of the glass capillary and adjust the conditions from guiding at room temperature to simple geometrical transmission at elevated temperatures. This holds the promise to investigate the effect of conductivity on particle transport (build-up and removal of charge patches) through capillaries in more details

  1. Teleradiology and PACS - strategy of the Innsbruck University Hospital; Teleradiologie und PACS - das Konzept des Universitaetsklinikums Innsbruck

    Energy Technology Data Exchange (ETDEWEB)

    Vogl, R. [HITT - Health Information Technologies Tirol, Innsbruck (Austria)

    2005-08-01

    Systems for management of digital imaging data are very important and widespread at the Innsbruck University Hospital and constitute a central component of the IT strategies followed by the hospital operating company TILAK (Tyrolean public hospitals). The particular goal is to integrate all imaging data into the electronic medical records and make these available online to each of the approx. 2500 clinic workstations and ensure electronic data exchange with other healthcare services. Teleradiology connections have been established at the University Clinic for Radiology since 1995; these have been continually expanded and linked to the central PACS. An eHealth web portal was recently established to facilitate transfer of images and findings from TILAK hospitals to other healthcare organizations. Registered users can be cleared for a limited time to access all radiological imaging data via this web portal. (orig.) [German] Die Systeme zum digitalen Bilddatenmanagement haben grosse Bedeutung und weite Verbreitung an der Universitaetsklinik Innsbruck und sind zentraler Bestandteil der IT-Strategie der Krankenhausbetreibergesellschaft TILAK (Tiroler Landeskrankenanstalten). Ziel dabei ist es insbesondere, saemtliche Bilddaten in die elektronische Krankengeschichte zu integrieren und von jedem der ca. 2500 klinischen Arbeitsplaetze aus online zugreifbar zu machen sowie den elektronischen Datenaustausch mit anderen Gesundheitsdiensteanbietern zu gewaehrleisten. Seit 1995 bestehen Teleradiologieverbindungen der Universitaetsklinik fuer Radiologie; diese wurden laufend ausgebaut und die Einbindung in das zentrale PACS hergestellt. Zur Kommunikation von Bild- und Befunddaten aus den Krankenhaeusern der TILAK an andere Gesundheitseinrichtungen wurde kuerzlich ein eHealth WebPortal geschaffen, ueber das saemtliche radiologischen Bilddaten durch zeitbefristete Freigaben fuer registrierte Benutzer zugaenglich gemacht werden koennen. (orig.)

  2. Open Label Pilot Study of Modafinil for Methamphetamine Dependence1

    Science.gov (United States)

    McGaugh, Janette; Mancino, Michael J.; Feldman, Zachary; Chopra, Mohit P.; Gentry, W. Brooks; Cargile, Christopher; Oliveto, Alison

    2013-01-01

    Methamphetamine has become a major public health issue in both the US and globally. Despite this, no effective pharmacotherapy for methamphetamine abuse has been developed to date. This 6 week, open-label pilot clinical trial examined the safety and tolerability of modafinil up to 400mg/day in eight methamphetamine dependent individuals. Subjects were inducted onto modafinil at 400 mg/day over three days and remained on 400 mg/day for 4.5 weeks. Participants received weekly blister packs and underwent weekly individual cognitive behavioral therapy. Adjunctive contingency management procedures were used to enhance retention. Vital signs and supervised urine samples were obtained thrice weekly and self-reported drug use and Hamilton Anxiety and Depression ratings were completed once weekly. Eight subjects (50% female, 100% Caucasian, aged 35-52 yrs) were enrolled. Four completed the 6-wk study, 3 completed a portion and one withdrew consent before completing intake. Results showed that systolic blood pressure (t=1.09, p=0.28), diastolic blood pressure, (t=1.18, p=0.24) and heart rate (t=1.55, p=0.13) did not change over time. Scores on the modafinil side effects checklist (t=−2.63, p=0.01), Hamilton Anxiety scale (t=−2.50, p=0.018) and Hamilton Depression scale (t=−3.25, p=0.003) all decreased over time. The proportion of urine positive for amphetamines did not change over time (t=−0.52, p=0.61), whereas self-reported methamphetamine use did (t=−2.86, p<0.005). These results suggest that modafinil at 400 mg/day is safe and tolerable for methamphetamine dependent individuals. PMID:19745650

  3. Determination of the size of an imaging data storage device at a full PACS hospital

    International Nuclear Information System (INIS)

    Cha, S. J.; Kim, Y. H.; Hur, G.

    2000-01-01

    To determine the appropriate size of a short and long-term storage device, bearing in mind the design factors involved and the installation costs. The number of radiologic studies quoted is the number of these undertaken during a one-year period at a university hospital with 650 beds, and reflects the actual number of each type of examination performed at a full PACS hospital. The average daily number of outpatients was 1586, while that of inpatients was 639.5. The numbers of radiologic studies performed were as follows : 378 among 189 outpatients, and 165 among 41 inpatients. The average daily number of examinations was 543, comprising 460 CR, 30 ultrasonograms, 25 CT, 8 MRI, 20 others. The total amount of digital images was 17.4 GB per day, while the amount of short-term data with lossless compression was 6.7 GB per day. During 14 days short-term storage, the amount of image data was 93.7 GB in disk array. The amount of data stored mid term (1 year), with lossy compression, was 369.1 GB. The amount of data stored in the form of long-term cache and educational images was 38.7 GB and 30 GB, respectively, The total size of disk array was 531.5 GB. A device suitable for the long-term storage of images, for at least five years, requires a capacity of 1845.5 GB. At a full PACS hospital with 600 beds, the minimum disk space required for the short-and mid-term storage of image data in disk array is 540 GB. The capacity required for long term storage (at least five years) is 1900 GB. (author)

  4. Complete Genome Sequences of Eight Helicobacter pylori Strains with Different Virulence Factor Genotypes and Methylation Profiles, Isolated from Patients with Diverse Gastrointestinal Diseases on Okinawa Island, Japan, Determined Using PacBio Single-Molecule Real-Time Technology

    Science.gov (United States)

    Shiroma, Akino; Teruya, Kuniko; Shimoji, Makiko; Nakano, Kazuma; Juan, Ayaka; Tamotsu, Hinako; Terabayashi, Yasunobu; Aoyama, Misako; Teruya, Morimi; Suzuki, Rumiko; Matsuda, Miyuki; Sekine, Akihiro; Kinjo, Nagisa; Kinjo, Fukunori; Yamaoka, Yoshio; Hirano, Takashi

    2014-01-01

    We report the complete genome sequences of eight Helicobacter pylori strains isolated from patients with gastrointestinal diseases in Okinawa, Japan. Whole-genome sequencing and DNA methylation detection were performed using the PacBio platform. De novo assembly determined a single, complete contig for each strain. Furthermore, methylation analysis identified virulence factor genotype-dependent motifs. PMID:24744331

  5. Sphere-pac fuel development program. First semi-annual progress report, October 1979-March 1980

    International Nuclear Information System (INIS)

    Felt, R.E.

    1980-05-01

    Development of processes by Exxon Nuclear Company, Inc. for fabricating spherical particle nuclear fuel (sphere-pac) during October 1979 through March 1980 is reported. The program surveyed available technology to develop an initial flowsheet as a design basis for process development. An 0.1 ton/day pilot plant was built to develop and demonstrate the fabrication of sphere-pac fuel. Process and equipment efforts have been directed towards the demonstration of processes and equipment necessary to fabricate sphere-pac fuel on a commercial scale

  6. Surgical PACS for the digital operating room. Systems engineering and specification of user requirements.

    Science.gov (United States)

    Korb, Werner; Bohn, Stefan; Burgert, Oliver; Dietz, Andreas; Jacobs, Stephan; Falk, Volkmar; Meixensberger, Jürgen; Strauss, Gero; Trantakis, Christos; Lemke, Heinz U

    2006-01-01

    For better integration of surgical assist systems into the operating room, a common communication and processing plattform that is based on the users needs is needed. The development of such a system, a Surgical Picture Aquisition and Communication System (S-PACS), according the systems engineering cycle is oulined in this paper. The first two steps (concept and specification) for the engineering of the S-PACS are discussed.A method for the systematic integration of the users needs', the Quality Function Deployment (QFD), is presented. The properties of QFD for the underlying problem and first results are discussed. Finally, this leads to a first definition of an S-PACS system.

  7. PAC learning using Nadaraya-Watson estimator based on orthonormal systems

    Energy Technology Data Exchange (ETDEWEB)

    Qiao, Hongzhu [Fort Valley State College, GA (United States). Dept. of Mathematics and Physics; Rao, N.S.V.; Protopopescu, V. [Oak Ridge National Lab., TN (United States)

    1997-08-01

    Regression or function classes of Euclidean type with compact support and certain smoothness properties are shown to be PAC learnable by the Nadaraya-Watson estimator based on complete orthonormal systems. While requiring more smoothness properties than typical PAC formulations, this estimator is computationally efficient, easy to implement, and known to perform well in a number of practical applications. The sample sizes necessary for PAC learning of regressions or functions under sup norm cost are derived for a general orthonormal system. The result covers the widely used estimators based on Haar wavelets, trignometric functions, and Daubechies wavelets.

  8. Evaluation of radiological workstations and web-browser-based image distribution clients for a PACS project in hands-on workshops

    International Nuclear Information System (INIS)

    Boehm, Thomas; Handgraetinger, Oliver; Voellmy, Daniel R.; Marincek, Borut; Wildermuth, Simon; Link, Juergen; Ploner, Ricardo

    2004-01-01

    The methodology and outcome of a hands-on workshop for the evaluation of PACS (picture archiving and communication system) software for a multihospital PACS project are described. The following radiological workstations and web-browser-based image distribution software clients were evaluated as part of a multistep evaluation of PACS vendors in March 2001: Impax DS 3000 V 4.1/Impax Web1000 (Agfa-Gevaert, Mortsel, Belgium); PathSpeed V 8.0/PathSpeed Web (GE Medical Systems, Milwaukee, Wis., USA); ID Report/ID Web (Image Devices, Idstein, Germany); EasyVision DX/EasyWeb (Philips Medical Systems, Eindhoven, Netherlands); and MagicView 1000 VB33a/MagicWeb (Siemens Medical Systems, Erlangen, Germany). A set of anonymized DICOM test data was provided to enable direct image comparison. Radiologists (n=44) evaluated the radiological workstations and nonradiologists (n=53) evaluated the image distribution software clients using different questionnaires. One vendor was not able to import the provided DICOM data set. Another vendor had problems in displaying imported cross-sectional studies in the correct stack order. Three vendors (Agfa-Gevaert, GE, Philips) presented server-client solutions with web access. Two (Siemens, Image Devices) presented stand-alone solutions. The highest scores in the class of radiological workstations were achieved by ID Report from Image Devices (p<0.005). In the class of image distribution clients, the differences were statistically not significant. Questionnaire-based evaluation was shown to be useful for guaranteeing systematic assessment. The workshop was a great success in raising interest in the PACS project in a large group of future clinical users. The methodology used in the present study may be useful for other hospitals evaluating PACS. (orig.)

  9. Structural Analysis of Mycobacterium tuberculosis Homologues of the Eukaryotic Proteasome Assembly Chaperone 2 (PAC2).

    Science.gov (United States)

    Bai, Lin; Jastrab, Jordan B; Isasa, Marta; Hu, Kuan; Yu, Hongjun; Gygi, Steven P; Darwin, K Heran; Li, Huilin

    2017-05-01

    A previous bioinformatics analysis identified the Mycobacterium tuberculosis proteins Rv2125 and Rv2714 as orthologs of the eukaryotic proteasome assembly chaperone 2 (PAC2). We set out to investigate whether Rv2125 or Rv2714 can function in proteasome assembly. We solved the crystal structure of Rv2125 at a resolution of 3.0 Å, which showed an overall fold similar to that of the PAC2 family proteins that include the archaeal PbaB and the yeast Pba1. However, Rv2125 and Rv2714 formed trimers, whereas PbaB forms tetramers and Pba1 dimerizes with Pba2. We also found that purified Rv2125 and Rv2714 could not bind to M. tuberculosis 20S core particles. Finally, proteomic analysis showed that the levels of known proteasome components and substrate proteins were not affected by disruption of Rv2125 in M. tuberculosis Our work suggests that Rv2125 does not participate in bacterial proteasome assembly or function. IMPORTANCE Although many bacteria do not encode proteasomes, M. tuberculosis not only uses proteasomes but also has evolved a posttranslational modification system called pupylation to deliver proteins to the proteasome. Proteasomes are essential for M. tuberculosis to cause lethal infections in animals; thus, determining how proteasomes are assembled may help identify new ways to combat tuberculosis. We solved the structure of a predicted proteasome assembly factor, Rv2125, and isolated a genetic Rv2125 mutant of M. tuberculosis Our structural, biochemical, and genetic studies indicate that Rv2125 and Rv2714 do not function as proteasome assembly chaperones and are unlikely to have roles in proteasome biology in mycobacteria. Copyright © 2017 American Society for Microbiology.

  10. PKA, novel PKC isoforms, and ERK is mediating PACAP auto-regulation via PAC1R in human neuroblastoma NB-1 cells

    DEFF Research Database (Denmark)

    Georg, Birgitte; Falktoft, Birgitte; Fahrenkrug, Jan

    2016-01-01

    kinase inhibitors revealed that both PKA and novel but not conventional PKC isozymes were involved in the PACAP auto-regulation. Inhibition of MAPK/ERK kinase (MEK) also impeded the induction, and we found that PKA, novel PKC and ERK acted in parallel and were thus not part of the same pathways....... The expression of the transcription factor EGR1 previously ascribed as target of PACAP signalling was found to be transiently induced by PACAP and pharmacological inhibition of either PKC or MEK1/2 abolished PACAP mediated EGR1 induction. In contrast, inhibition of PKA mediated increased PACAP mediated EGR1...... by activation of PAC1R, and that the signalling is different from the PAC1R signalling mediating induction of VIP in the same cells. PACAP auto-regulation depends on parallel activation of PKA, novel PKC isoforms, and ERK, while EGR1 does not seem to be part of the PACAP auto-regulation....

  11. Electrophoretic nature and evaluation of poly-aluminum-chloride-sulfate (PACS) as a coagulant for water and wastewater treatment.

    Science.gov (United States)

    Gao, Bao-yu; Yue, Qin-yan; Wang, Bing-jian

    2003-05-01

    A series of poly-aluminum-chloride-sulfates (PACS), which have different OH/Al (gamma) and Al(3+)/SO4(2-) mole ratios, has been prepared using AlCl3 x 6H2O, A(SO4)3 x 18H2O and Na2CO3 as raw materials. The electrophoretic nature of PACS was investigated by electrophoresis. Laboratory experiments were undertaken to evaluate the PACS in comparison with polyaluminum chloride (PAC) for the coagulation of simulating water and actual wastewaters. The experimental results show that the gamma value and the Al(3+)/SO4(2-) mole ratio affect the electrophoretic nature of PACS. PACS has a maximum zeta potential at about a gamma value of 1.5 and Al(3+)/SO4(2-) mole ratio of 12-16. The zeta potential of PACS varies with pH. The performance of PACS as coagulant is affected by gamma value and Al(3+)/SO4(2-) mole ratio. PACS of gamma = 2.1 and Al(3+)/SO4(2-) = 15 gives best turbidity removal effectiveness. In comparison with PAC of gamma = 2.0, PACS of gamma = 2.0 and Al(3+)/SO4(2-) = 16 gives higher removal efficiency for turbidity and COD, and shows the following advantages in the clarification of waters and wastewaters: rapid aggregation velocity, larger and heavier flocs, and lower required dosage.

  12. Atmospheric oxidation of N-PAC and nitro substituted N-PAC in water droplets

    DEFF Research Database (Denmark)

    Feilberg, A.; Holcman, J.; Nielsen, T.

    1999-01-01

    A pulse radiolysis technique was used to study the formation of OH-adducts of quinoline (Q) and 5-nitroquinoline (5NQ) and the subsequent reactions of the OH-adducts with O-2 in both acidic and alkaline aqueous solution. The rate constants in alkaline solution were: k(Q+OH) = (9.0+/-1.0)lozenge 10...

  13. Incidental lung nodules on CT examinations of the abdomen: Prevalence and reporting rates in the PACS era

    Energy Technology Data Exchange (ETDEWEB)

    Rinaldi, Maria Francesca [Radiologia III - Azienda Ospedaliera Pol. S.Orsola-Malpighi, via Massarenti 9 - 40138 Bologna (Italy); Bartalena, Tommaso, E-mail: t.bartalena@email.i [Radiologia III - Azienda Ospedaliera Pol. S.Orsola-Malpighi, via Massarenti 9 - 40138 Bologna (Italy); Giannelli, Giovanni; Rinaldi, Giovanni [Radiologia III - Azienda Ospedaliera Pol. S.Orsola-Malpighi, via Massarenti 9 - 40138 Bologna (Italy); Sverzellati, Nicola [Dipartimento di Scienze Cliniche, sezione di Radiologia - Universita di Parma, via Gramsci 14 - 43100 Parma (Italy); Canini, Romeo [Dipartimento Clinico di Scienze Radiologiche ed Istocitopatologiche, divisione di Diagnostica per Immagini - Universita di Bologna, via Massarenti 9 - 40138 Bologna (Italy); Gavelli, Giampaolo [Servizio di Diagnostica per Immagini, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (I.R.S.T.), via Piero Maroncelli, 40 - 47014 Meldola (Italy)

    2010-06-15

    Objectives: To retrospectively evaluate prevalence, reporting rates and clinical implications of incidental pulmonary nodules detected in multidetector computed tomography (MDCT) abdominal studies. Materials and methods: Abdominal MDCT studies of 243 consecutive patients, 94 of whom had a history of cancer, were evaluated. Lung bases included in the scan were reviewed on a PACS workstation with different window settings and post-processing techniques. Nodules were classified according to their density (calcified, solid noncalcified, non-solid, part-solid) and size (<4 mm; 4-6 mm; 6-8 mm; >8 mm). The study findings were compared with the corresponding radiologic reports. Previous of following CT studies, when available from the PACS, were also reviewed to evaluate changes in number and size of the detected nodules. Results: An average of 8.2 cm of lung parenchyma was imaged in each patient. 213 noncalcified nodules (NCNs) were identified in 95 patients (39.1%) but only 8 patients (8.4%) had it mentioned in the final report. Comparison CT studies were available for 44 out of the 95 positive patients showing disappearance of the nodules in 2 cases, no interval change in 26 and progression in size and/or number in 16 patients, in whom a final diagnosis of metastasis or primary lung cancers was achieved. Conclusion: Radiologists tend to overlook lung portions on abdominal CT studies. Underreporting may affect patient care and have medico-legal implications since images are permanently stored in digital format on PACS and CD-ROMs. Management of the discovered nodules should be tailored to the clinical situation of the patient, and particular care should be reserved to patients with oncologic history.

  14. Abandonment of nicotine dependence treatment: A cohort study

    Directory of Open Access Journals (Sweden)

    Maritza Muzzi Cardozo Pawlina

    Full Text Available CONTEXT AND OBJECTIVE: Non-adherence to treatment is one of the hindering factors in the process of smoking cessation. This study aimed to compare sociodemographic characteristics, smoking status and motivation among smokers who maintained or abandoned treatment to stop smoking, and to analyze associations between sociodemographic factors and smoking. DESIGN AND SETTING: Cohort study on 216 smokers who were attended at healthcare units in Cuiabá, Mato Grosso. METHODS: The instruments used were the Fagerström, URICA and CAGE questionnaires. Data from the initial evaluation was analyzed using the two-proportion test (α < 0.05. The patients were monitored for six months and those who abandoned treatment were accounted for. Bivariate analysis was conducted, using crude prevalence ratios and 5% significance level (P < 0.05, with abandonment of treatment as the outcome variable. Associations with P < 0.20 were selected for multiple robust Poisson regression (RPa. RESULTS: The abandonment rate was 34.26%. Males and individuals in the 20-39 age group, in employment, with low motivation, with shorter time smoking and lower tobacco intake predominated in the dropout group. In the final model, gender (RPa 1.47; 95% CI: 1.03-2.10 and age group (RPa 3.77; 95% CI: 1.47-9.67 remained associated with abandonment. CONCLUSION: Males and individuals in the 20-39 age group, in employment, with low motivation, with shorter time smoking and lower tobacco intake more frequently abandoned the treatment. Male gender and younger age group were associated with abandonment of nicotine dependence treatment.

  15. Los manglares de Costa Rica: el Pacífico norte

    Directory of Open Access Journals (Sweden)

    Priscilla Zamora-Trejos

    2009-09-01

    del Pacífico norte de Costa Rica, y del resto del país son necesarios y urgentes.Abstract: Costa Rica mangroves: the north Pacific. Costa Rica has mangrove forests on both the Caribbean and Pacific coasts. The Pacific side has 99% of the mangrove area of the country. In this review we compile available information on the mangroves of the north Pacific coast of Costa Rica, from Bahía Salinas, on the border with Nicaragua, to the tip of the Peninsula de Nicoya at Cabo Blanco. We provide information on the location of the mangroves and all available information for each mangrove forest. These mangrove communities are smaller in extension and tree sizes, and have lower diversity compared to the mangroves on the southern section of the Pacific coast of Costa Rica. The dominant species are Rhizophora mangle and Rhizophora racemosa along the canal edges, backed by Avicennia germinans, and farther inland Avicennia bicolor, Laguncularia racemosa and Conocarpus erectus. At Potrero Grande a healthy population of Pelliciera rhizophorae, a rare species, has been reported. We recognized 38 mangrove communities in this part of the country, based on the National Wetland Inventory, published papers, field observations, theses, technical reports, and the national topographic maps (1:50 000, Instituto Geográfico Nacional. Relatively detailed information could be found for only five mangrove forests, for 14 more only prelimary and incomplete lists of plants and in some cases of animal species are available, for nine there is even less information, and for nine more only their location is known, which in some cases was not correct. Detail mapping, characterization of the vegetation and fauna, physiological studies, analyses of biogeochemical and physical processes, economic valuations, and determination of the health status of the mangrove of the northern Pacific coast, as well as for the rest of Costa Rica, are neccesary and urgent. Rev. Biol. Trop. 57 (3: 473-488. Epub 2009

  16. PacIOOS Nearshore Sensor 03 (NS03): Hilton Hawaiian Pier, Oahu, Hawaii

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The nearshore sensors are part of the Pacific Islands Ocean Observing System (PacIOOS) and are designed to measure a variety of ocean parameters at fixed point...

  17. PacIOOS Ocean Gliders: SeaGlider 139: Mission 7

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — As a part of PacIOOS, ocean gliders provide very detailed information about the physical and chemical condition of the waters around the Hawaiian Islands....

  18. PacIOOS Ocean Gliders: SeaGlider 139: Mission 1

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — As a part of PacIOOS, ocean gliders provide very detailed information about the physical and chemical condition of the waters around the Hawaiian Islands....

  19. PacIOOS Ocean Gliders: SeaGlider 114: Mission 3

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — As a part of PacIOOS, ocean gliders provide very detailed information about the physical and chemical condition of the waters around the Hawaiian Islands....

  20. PacIOOS Ocean Gliders: SeaGlider 114: Mission 4

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — As a part of PacIOOS, ocean gliders provide very detailed information about the physical and chemical condition of the waters around the Hawaiian Islands....

  1. PacIOOS Ocean Gliders: SeaGlider 139: Mission 6

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — As a part of PacIOOS, ocean gliders provide very detailed information about the physical and chemical condition of the waters around the Hawaiian Islands....

  2. PacIOOS Ocean Gliders: SeaGlider 523: Mission 3

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — As a part of PacIOOS, ocean gliders provide very detailed information about the physical and chemical condition of the waters around the Hawaiian Islands....

  3. PacIOOS Water Quality Buoy 04 (WQB-04): Hilo Bay, Big Island, Hawaii

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The water quality buoys are part of the Pacific Islands Ocean Observing System (PacIOOS) and are designed to measure a variety of ocean parameters at fixed points....

  4. PacIOOS Water Quality Buoy 03 (WQB-03): Kiholo Bay, Big Island, Hawaii

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The water quality buoys are part of the Pacific Islands Ocean Observing System (PacIOOS) and are designed to measure a variety of ocean parameters at fixed points....

  5. PacIOOS Water Quality Buoy KN (WQB-KN): Kilo Nalu, Oahu, Hawaii

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The water quality buoys are part of the Pacific Islands Ocean Observing System (PacIOOS) and are designed to measure a variety of ocean parameters at fixed points....

  6. PacIOOS Ocean Gliders: SeaGlider 139: Mission 3

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — As a part of PacIOOS, ocean gliders provide very detailed information about the physical and chemical condition of the waters around the Hawaiian Islands....

  7. Medical Data Manager an Interface between PACS and the gLite Data Management System

    CERN Document Server

    Montagnat, Johan; Texier, Romain; Nienartowicz, Krzysztof; Baud, Jean-Philippe

    2008-01-01

    The medical imaging community uses the DICOM image format and protocol to store and exchange data. The Medical Data Manager (MDM) is an interface between DICOM compliant systems such as PACS and the EGEE Data Management System. It opens hospital imaging networks to the world scale Grid while protecting sensitive medical data. It can be accessed transparently from any gLite service. It is an important milestone towards adoption of Grid technologies in the medical imaging community. Hospitals continuously produce tremendous amounts of image data that is managed by local PACS (Picture Archiving and Communication Systems). These systems are often limited to a local network access although the community experiences a growing interest for data sharing and remote processing. Indeed, patient data is often spread out different medical data acquisition centers. Furthermore, researchers in the area often need to analyze large populations whose data can be gathered through federations of PACS. Opening PACS to the outer I...

  8. PacIOOS Nearshore Sensor 02 (NS02): Hawaii Yacht Club, Oahu, Hawaii

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The nearshore sensors are part of the Pacific Islands Ocean Observing System (PacIOOS) and are designed to measure a variety of ocean parameters at fixed point...

  9. PacIOOS Nearshore Sensor 13 (NS13): Kahului, Maui, Hawaii

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The nearshore sensors are part of the Pacific Islands Ocean Observing System (PacIOOS) and are designed to measure a variety of ocean parameters at fixed point...

  10. PacIOOS Nearshore Sensor 01 (NS01): Waikiki Yacht Club, Oahu, Hawaii

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The nearshore sensors are part of the Pacific Islands Ocean Observing System (PacIOOS) and are designed to measure a variety of ocean parameters at fixed point...

  11. PacIOOS Nearshore Sensor 15 (NS15): Pago Bay, Guam

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The nearshore sensors are part of the Pacific Islands Ocean Observing System (PacIOOS) and are designed to measure a variety of ocean parameters at fixed point...

  12. Workshop for Open Source Universal Picture Archiving and Communication Systems (PACS)

    National Research Council Canada - National Science Library

    Tohme, Walid G

    2006-01-01

    .... The "Open Source Universal PACS Archive" workshop focused on current challenges of and open source solutions to the management of images and other clinical information in multi-center settings...

  13. PacIOOS Nearshore Sensor 10 (NS10): Maunalua Bay, Oahu, Hawaii

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The nearshore sensors are part of the Pacific Islands Ocean Observing System (PacIOOS) and are designed to measure a variety of ocean parameters at fixed point...

  14. PacIOOS Ocean Gliders: SeaGlider 139: Mission 9

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — As a part of PacIOOS, ocean gliders provide very detailed information about the physical and chemical condition of the waters around the Hawaiian Islands....

  15. PacIOOS Ocean Gliders: SeaGlider 139: Mission 8

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — As a part of PacIOOS, ocean gliders provide very detailed information about the physical and chemical condition of the waters around the Hawaiian Islands....

  16. PacIOOS Ocean Gliders: SeaGlider 523: Mission 1

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — As a part of PacIOOS, ocean gliders provide very detailed information about the physical and chemical condition of the waters around the Hawaiian Islands....

  17. PacIOOS Water Quality Buoy AW (WQB-AW): Ala Wai, Oahu, Hawaii

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The water quality buoys are part of the Pacific Islands Ocean Observing System (PacIOOS) and are designed to measure a variety of ocean parameters at fixed points....

  18. PacIOOS Ocean Gliders: SeaGlider 523: Mission 4

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — As a part of PacIOOS, ocean gliders provide very detailed information about the physical and chemical condition of the waters around the Hawaiian Islands....

  19. PacIOOS Ocean Gliders: SeaGlider 139: Mission 2

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — As a part of PacIOOS, ocean gliders provide very detailed information about the physical and chemical condition of the waters around the Hawaiian Islands....

  20. Cloning and expression profiling of the PacSnRK2 and PacPP2C gene families during fruit development, ABA treatment, and dehydration stress in sweet cherry.

    Science.gov (United States)

    Shen, Xinjie; Guo, Xiao; Zhao, Di; Zhang, Qiang; Jiang, Yuzhuang; Wang, Yantao; Peng, Xiang; Wei, Yan; Zhai, Zefeng; Zhao, Wei; Li, Tianhong

    2017-10-01

    Plant SNF1-related protein kinase 2 (SnRK2) and protein phosphatase 2C (PP2C) family members are core components of the ABA signal transduction pathway. SnRK2 and PP2C proteins have been suggested to play crucial roles in fruit ripening and improving plant tolerance to drought stress, but supporting genetic information has been lacking in sweet cherry (Prunus avium L.). Here, we cloned six full-length SnRK2 genes and three full-length PP2C genes from sweet cherry cv. Hong Deng. Quantitative PCR analysis revealed that PacSnRK2.2, PacSnRK2.3, PacSnRK2.6, and PacPP2C1-3 were negatively regulated in fruits in response to exogenous ABA treatment, PacSnRK2.4 and PacSnRK2.5 were upregulated, and PacSnRK2.1 expression was not affected. The ABA treatment also significantly promoted the accumulation of anthocyanins in sweet cherry fruit. The expression of all PacSnRK2 and PacPP2C genes was induced by dehydration stress, which also promoted the accumulation of drought stress signaling molecules in the sweet cherry fruits, including ABA, soluble sugars, and anthocyanin. Furthermore, a yeast two-hybrid analysis demonstrated that PacPP2C1 interacts with all six PacSnRK2s, while PacPP2C3 does not interact with PacSnRK2.5. PacPP2C2 does not interact with PacSnRK2.1 or PacSnRK2.4. These results indicate that PacSnRK2s and PacPP2Cs may play a variety of roles in the sweet cherry ABA signaling pathway and the fruit response to drought stress. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  1. CO ICE PHOTODESORPTION: A WAVELENGTH-DEPENDENT STUDY

    International Nuclear Information System (INIS)

    Fayolle, Edith C.; Linnartz, Harold; Bertin, Mathieu; Romanzin, Claire; Michaut, Xavier; Fillion, Jean-Hugues; Oeberg, Karin I.

    2011-01-01

    UV-induced photodesorption of ice is a non-thermal evaporation process that can explain the presence of cold molecular gas in a range of interstellar regions. Information on the average UV photodesorption yield of astrophysically important ices exists for broadband UV lamp experiments. UV fields around low-mass pre-main-sequence stars, around shocks and in many other astrophysical environments are however often dominated by discrete atomic and molecular emission lines. It is therefore crucial to consider the wavelength dependence of photodesorption yields and mechanisms. In this work, for the first time, the wavelength-dependent photodesorption of pure CO ice is explored between 90 and 170 nm. The experiments are performed under ultra high vacuum conditions using tunable synchrotron radiation. Ice photodesorption is simultaneously probed by infrared absorption spectroscopy in reflection mode of the ice and by quadrupole mass spectrometry of the gas phase. The experimental results for CO reveal a strong wavelength dependence directly linked to the vibronic transition strengths of CO ice, implying that photodesorption is induced by electronic transition (DIET). The observed dependence on the ice absorption spectra implies relatively low photodesorption yields at 121.6 nm (Lyα), where CO barely absorbs, compared to the high yields found at wavelengths coinciding with transitions into the first electronic state of CO (A 1 Π at 150 nm); the CO photodesorption rates depend strongly on the UV profiles encountered in different star formation environments.

  2. HIPAA-compliant automatic monitoring system for RIS-integrated PACS operation

    Science.gov (United States)

    Jin, Jin; Zhang, Jianguo; Chen, Xiaomeng; Sun, Jianyong; Yang, Yuanyuan; Liang, Chenwen; Feng, Jie; Sheng, Liwei; Huang, H. K.

    2006-03-01

    As a governmental regulation, Health Insurance Portability and Accountability Act (HIPAA) was issued to protect the privacy of health information that identifies individuals who are living or deceased. HIPAA requires security services supporting implementation features: Access control; Audit controls; Authorization control; Data authentication; and Entity authentication. These controls, which proposed in HIPAA Security Standards, are Audit trails here. Audit trails can be used for surveillance purposes, to detect when interesting events might be happening that warrant further investigation. Or they can be used forensically, after the detection of a security breach, to determine what went wrong and who or what was at fault. In order to provide security control services and to achieve the high and continuous availability, we design the HIPAA-Compliant Automatic Monitoring System for RIS-Integrated PACS operation. The system consists of two parts: monitoring agents running in each PACS component computer and a Monitor Server running in a remote computer. Monitoring agents are deployed on all computer nodes in RIS-Integrated PACS system to collect the Audit trail messages defined by the Supplement 95 of the DICOM standard: Audit Trail Messages. Then the Monitor Server gathers all audit messages and processes them to provide security information in three levels: system resources, PACS/RIS applications, and users/patients data accessing. Now the RIS-Integrated PACS managers can monitor and control the entire RIS-Integrated PACS operation through web service provided by the Monitor Server. This paper presents the design of a HIPAA-compliant automatic monitoring system for RIS-Integrated PACS Operation, and gives the preliminary results performed by this monitoring system on a clinical RIS-integrated PACS.

  3. Poetry and cultural identity in F. T. Pacéré's writing: from identity ...

    African Journals Online (AJOL)

    My concern is the socio-cultural characteristics of F. T. Pacéré's poetry and their aesthetic and semantic structuring role. Pacéré's poetry is not just about identity affirmation; it is also about being open to the world, namely other people and other cultures. Through this, it seeks to achieve universal humanism. I conclude my ...

  4. Efektifitas Poly Aluminium Chloride (PAC) pada Pengolahan Limbah Lumpur Pemboran Sumur Minyak

    OpenAIRE

    ', Yustinawati '; ', Nirwana '; HS, Irdoni '

    2014-01-01

    Handling on waste oil drilling mud in research area uses an integrated sludge waste treatment method known as Mud Centralized Treatment Facility (CMTF). One processing stage performed in CMTF is chemical treatment using aluminum sulfate coagulant where the process of coagulation is optimum yet because there were still contain sediment solids. Poly Aluminium Chloride (PAC) thus becomes an alternative coagulant for the treatment because the main properties of colloidal particles in PAC do coagu...

  5. EyePACS: an adaptable telemedicine system for diabetic retinopathy screening.

    Science.gov (United States)

    Cuadros, Jorge; Bresnick, George

    2009-05-01

    Annual retinal screening of patients with diabetes is the standard clinical practice to prevent visual impairment and blindness from diabetic retinopathy. Telemedicine-based diabetic retinopathy screening (DRS) in primary care settings can effectively detect sight-threatening retinopathy and significantly increase compliance with annual retinal exams. EyePACS is a license-free Web-based DRS system designed to simplify the process of image capture, transmission, and review. The system provides a flexible platform for collaboration among clinicians about diabetic retinopathy. Primary clinic personnel (i.e., nursing, technical, or administrative staff) are trained and certified by the EyePACS program to acquire retinal images from standard digital retinal cameras. Relevant clinical data and eight high-resolution images per patient (two external and six retinal images) are encrypted and transmitted to a secure Internet server, using a standard computer and Web browser. Images are then interpreted by certified EyePACS reviewers or local eye care providers who are certified through the EyePACS Retinopathy Grading System. Reports indicating retinopathy level and referral recommendations are transmitted back to primary care providers through the EyePACS Web site or through interfaces between EyePACS and Health Level 7-compliant electronic medical records or chronic disease registries. The pilot phase of the EyePACS DRS program in California (2005-2006) recorded 3562 encounters. Since 2006, EyePACS has been expanded to over 120 primary care sites throughout California and elsewhere recording over 34,000 DRSs. The overall rate of referral is 8.21% for sight-threatening retinopathy and 7.83% for other conditions (e.g., cataract and glaucoma). The use of license-free Web-based software, standard interfaces, and flexible protocols has allowed primary care providers to adopt retinopathy screening with minimal effort and resources. 2009 Diabetes Technology Society.

  6. Far-infrared photometric observations of the outer planets and satellites with Herschel-PACS

    OpenAIRE

    Müller, T. G.; Balog, Z.; Nielbock, M.; Moreno, R.; Klaas, U.; Moór, A.; Linz, H.; Feuchtgruber, H.

    2016-01-01

    We present all Herschel PACS photometer observations of Mars, Saturn, Uranus, Neptune, Callisto, Ganymede, and Titan. All measurements were carefully inspected for quality problems, were reduced in a (semi-)standard way, and were calibrated. The derived flux densities are tied to the standard PACS photometer response calibration, which is based on repeated measurements of five fiducial stars. The overall absolute flux uncertainty is dominated by the estimated 5% model uncertainty of the stell...

  7. CT and MR imaging acquisition performance in a neuroradiology PACS module 1-year clinical experience

    International Nuclear Information System (INIS)

    Lou, S.L.; Loloyan, M.; Weinberg, W.S.; Valentino, D.J.; Lufkin, R.B.; Hanafee, W.N.; Bentson, J.; Jabour, B.A.; Huang, H.K.

    1990-01-01

    This paper analyzes the operational efficiency of our neuroradiology PACS compared with conventional film-based management systems. The authors neuroradiology PACS module has been in clinical evaluation for 6 months. Three SUN microcomputers, two PC/ATs, and an automated optical disk library are connected through Ethernet. Software implemented at the TCP/IP level is used to transfer images from MR imagers and CT scanners to a viewing station. Performance measurements include the time elapsed at each stage of the system

  8. Platform independent implementation of DICOM-based miniPACS.

    Science.gov (United States)

    Grodzki, M; Mikolajczyk, K; Palko, T; Rudnicki, P; Szabatin, M

    1998-01-01

    Platform independence is an important issue for a software designed to run across a hospital environment which is practically always heterogeneous one. This paper presents a simple miniPACS solution designed over an existing Intranet (Internet limited to a local area network). Platform independence is achieved with Java programming language which allows resulting code to be executed on virtually all machines. System consists of a server application providing DICOM (Digital Imaging and Communications in Medicine) services and clients that can use these services over a TCP/IP connection. The server application is capable of an image storage and supports a query mechanism to allow access to stored data, thus the clients may perform two major functions: providing image data for archiving or image retrieval for viewing. Presented client application provides both these functions. It retrieves stored images for further processing and returns calculated results to the archive. The parts of the system are connected through a DICOM interface. Consequently the system architecture is open and any devices like scanners or viewing stations supporting specific DICOM services may be attached.

  9. Java-based PACS and reporting system for nuclear medicine

    Science.gov (United States)

    Slomka, Piotr J.; Elliott, Edward; Driedger, Albert A.

    2000-05-01

    In medical imaging practice, images and reports often need be reviewed and edited from many locations. We have designed and implemented a Java-based Remote Viewing and Reporting System (JaRRViS) for a nuclear medicine department, which is deployed as a web service, at the fraction of the cost dedicated PACS systems. The system can be extended to other imaging modalities. JaRRViS interfaces to the clinical patient databases of imaging workstations. Specialized nuclear medicine applets support interactive displays of data such as 3-D gated SPECT with all the necessary options such as cine, filtering, dynamic lookup tables, and reorientation. The reporting module is implemented as a separate applet using Java Foundation Classes (JFC) Swing Editor Kit and allows composition of multimedia reports after selection and annotation of appropriate images. The reports are stored on the server in the HTML format. JaRRViS uses Java Servlets for the preparation and storage of final reports. The http links to the reports or to the patient's raw images with applets can be obtained from JaRRViS by any Hospital Information System (HIS) via standard queries. Such links can be sent via e-mail or included as text fields in any HIS database, providing direct access to the patient reports and images via standard web browsers.

  10. A dependence modelling study of extreme rainfall in Madeira Island

    Science.gov (United States)

    Gouveia-Reis, Délia; Guerreiro Lopes, Luiz; Mendonça, Sandra

    2016-08-01

    The dependence between variables plays a central role in multivariate extremes. In this paper, spatial dependence of Madeira Island's rainfall data is addressed within an extreme value copula approach through an analysis of maximum annual data. The impact of altitude, slope orientation, distance between rain gauge stations and distance from the stations to the sea are investigated for two different periods of time. The results obtained highlight the influence of the island's complex topography on the spatial distribution of extreme rainfall in Madeira Island.

  11. Performance enhancement with powdered activated carbon (PAC) addition in a membrane bioreactor (MBR) treating distillery effluent

    International Nuclear Information System (INIS)

    Satyawali, Yamini; Balakrishnan, Malini

    2009-01-01

    This work investigated the effect of powdered activated carbon (PAC) addition on the operation of a membrane bioreactor (MBR) treating sugarcane molasses based distillery wastewater (spentwash). The 8 L reactor was equipped with a submerged 30 μm nylon mesh filter with 0.05 m 2 filtration area. Detailed characterization of the commercial wood charcoal based PAC was performed before using it in the MBR. The MBR was operated over 200 days at organic loading rates (OLRs) varying from 4.2 to 6.9 kg m -3 d -1 . PAC addition controlled the reactor foaming during start up and enhanced the critical flux by around 23%; it also prolonged the duration between filter cleaning. Operation at higher loading rates was possible and for a given OLR, the chemical oxygen demand (COD) removal was higher with PAC addition. However, biodegradation in the reactor was limited and the high molecular weight compounds were not affected by PAC supplementation. The functional groups on PAC appear to interact with the polysaccharide portion of the sludge, which may reduce its propensity to interact with the nylon mesh.

  12. Design criteria for a data base management system for a PACS at Georgetown University Hospital

    International Nuclear Information System (INIS)

    Fahey, F.H.; Wang, P.C.; Mun, S.K.; Choyke, P.L.; Benson, H.R.; Duerinckx, A.; Elliott, L.P.

    1986-01-01

    A major goal of a radiologic picture archival and communication system (PACS) is to increase the availability of the data to the users who require access to them. This is done by providing the data in a digital form which can be readily communicated and archived. In this manner, the PACS can be seen as a specific example of a data base managements system (DBMS). The PACS/DBMS should organize the data base in such a way as to provide its users with the data they require in a timely and efficient manner. The ability to integrate the variety of data into common data base should lead to a more complete and relevant representation of the available information. A PACS/DBMS is not only unique in the types of data contained in the data base and its different users but also in the volume of data that are entered into the system and transferred within the system each day. Consideration of these characteristics leads to the definition of functional criteria for the PACS/DBMS. This report discusses the criteria that will be used in the design of a DBMS for a PACS at Georgetown University Hospital. (Auth.)

  13. XDS-I Gateway Development for HIE Connectivity with Legacy PACS at Gil Hospital.

    Science.gov (United States)

    Simalango, Mikael Fernandus; Kim, Youngchul; Seo, Young Tae; Choi, Young Hwan; Cho, Yong Kyun

    2013-12-01

    The ability to support healthcare document sharing is imperative in a health information exchange (HIE). Sharing imaging documents or images, however, can be challenging, especially when they are stored in a picture archiving and communication system (PACS) archive that does not support document sharing via standard HIE protocols. This research proposes a standard-compliant imaging gateway that enables connectivity between a legacy PACS and the entire HIE. Investigation of the PACS solutions used at Gil Hospital was conducted. An imaging gateway application was then developed using a Java technology stack. Imaging document sharing capability enabled by the gateway was tested by integrating it into Gil Hospital's order communication system and its HIE infrastructure. The gateway can acquire radiology images from a PACS storage system, provide and register the images to Gil Hospital's HIE for document sharing purposes, and make the images retrievable by a cross-enterprise document sharing document viewer. Development of an imaging gateway that mediates communication between a PACS and an HIE can be considered a viable option when the PACS does not support the standard protocol for cross-enterprise document sharing for imaging. Furthermore, the availability of common HIE standards expedites the development and integration of the imaging gateway with an HIE.

  14. Temperature dependence studies on the electro-oxidation of ...

    Indian Academy of Sciences (India)

    Cyclic voltammetry; electrochemical impedance spectroscopy; activation energy; fuel cell; alcohol. Abstract. Temperature dependence on the electro-oxidation of methanol, ethanol and 1-propanol in 0.5 M H2SO4 were investigated with Pt and PtRu electrodes. Tafel slope and apparent activation energy were evaluated ...

  15. Temperature dependence studies on the electro-oxidation of ...

    Indian Academy of Sciences (India)

    Administrator

    Abstract. Temperature dependence on the electro-oxidation of methanol, ethanol and 1-propanol in. 0⋅5 M H2SO4 were investigated with Pt and PtRu electrodes. Tafel slope and apparent activation energy were evaluated from the cyclic voltammetric data in the low potential region (0⋅3–0⋅5 V vs SHE). The. CV results ...

  16. Study of dependence of magnetic properties on seeding ...

    Indian Academy of Sciences (India)

    hydroxides is facilitated which subsequently gives rise to a pure spinel phase. The average particle sizes of the spinel phase and of α-. Fe2O3 have been estimated from ..... Dependence of magnetic properties on seeding temperature in Cu0·25Co0·25Zn0·5Fe2O4. 1101. Duan J and Gregory J 2003 Adv. Colloid. Interf. Sci.

  17. Impact of a PACS/RIS-integrated speech recognition system on radiology reporting time and report availability

    International Nuclear Information System (INIS)

    Trumm, C.G.; Glaser, C.; Paasche, V.; Kuettner, B.; Francke, M.; Nissen-Meyer, S.; Reiser, M.; Crispin, A.; Popp, P.

    2006-01-01

    Purpose: Quantification of the impact of a PACS/RIS-integrated speech recognition system (SRS) on the time expenditure for radiology reporting and on hospital-wide report availability (RA) in a university institution. Material and Methods: In a prospective pilot study, the following parameters were assessed for 669 radiographic examinations (CR): 1. time requirement per report dictation (TED: dictation time (s)/number of images [examination] x number of words [report]) with either a combination of PACS/tape-based dictation (TD: analog dictation device/minicassette/transcription) or PACS/RIS/speech recognition system (RR: remote recognition/transcription and OR: online recognition/self-correction by radiologist), respectively, and 2. the Report Turnaround Time (RTT) as the time interval from the entry of the first image into the PACS to the available RIS/HIS report. Two equal time periods were chosen retrospectively from the RIS database: 11/2002-2/2003 (only TD) and 11/2003-2/2004 (only RR or OR with speech recognition system [SRS]). The midterm (≥24 h, 24 h intervals) and short-term (< 24 h, 1 h intervals), RA after examination completion were calculated for all modalities and for Cr, CT, MR and XA/DS separately. The relative increase in the mid-term RA (RIMRA: related to total number of examinations in each time period) and increase in the short-term RA (ISRA: ratio of available reports during the 1st to 24th hour) were calculated. Results: Prospectively, there was a significant difference between TD/RR/OR (n=151/257/261) regarding mean TED (0.44/0.54/0.62 s [per word and image]) and mean RTT (10.47/6.65/1.27 h), respectively. Retrospectively, 37 898/39 680 reports were computed from the RIS database for the time periods of 11/2002-2/2003 and 11/2003-2/2004. For CR/CT there was a shift of the short-term RA to the first 6 hours after examination completion (mean cumulative RA 20% higher) with a more than three-fold increase in the total number of available

  18. Predicting the transition from frequent cannabis use to cannabis dependence: a three-year prospective study

    NARCIS (Netherlands)

    van der Pol, Peggy; Liebregts, Nienke; de Graaf, Ron; Korf, Dirk J.; van den Brink, Wim; van Laar, Margriet

    2013-01-01

    Frequent cannabis users are at high risk of dependence, still most (near) daily users are not dependent. It is unknown why some frequent users develop dependence, whereas others do not. This study aims to identify predictors of first-incidence DSM-IV cannabis dependence in frequent cannabis users. A

  19. Predicting the transition from frequent cannabis use to cannabis dependence: a three-year prospective study.

    NARCIS (Netherlands)

    van der Pol, P.; Liebregts, N.; de Graaf, R.; Korf, D.J.; van den Brink, W.; van Laar, M.

    2013-01-01

    Background Frequent cannabis users are at high risk of dependence, still most (near) daily users are not dependent. It is unknown why some frequent users develop dependence, whereas others do not. This study aims to identify predictors of first-incidence DSM-IV cannabis dependence in frequent

  20. [Sewage sludge conditioning by bioleaching-dual PAC and PAM addition].

    Science.gov (United States)

    Liu, Chang-Geng; Zhang, Pan-Yue; Zeng, Guang-Ming; Liu, Yong-Gang

    2010-09-01

    Bioleaching-dual polyaluminum chloride (PAC) and polyacrylamide (PAM) addition was used to condition sewage sludge. The results showed that FeSO4 x 7H2O addition improved the bioleaching rate obviously with a fixed sulfur power dosage of 3 g x L(-1); when the FeSO4 x 7H2O dosage was 8 g x L(-1), the bioleaching lasted 1.5 d to decrease the sludge pH below 2. Bioleaching improved the sludge dewaterability significantly with a specific resistance to filtration (SRF) reduction of 77.52% from 6.45 x 10(10)s2 x g(-10 to 1.45 x 10(10)s2 x g(-1), but the bioleached sludge was still difficult to be dewatered. After adjusting the bioleached sludge pH to 6, PAC and PAM were used to enhance conditioning of the bioleached sludge. The results indicated that the optimal dosage was 200 mg x L(-1) for PAC or 50 mg x L(-1) for PAM when single chemical was used. When PAC and PAM were dually used, the optimal dosages of PAC and PAM were 100 mg x L(-1) and 25 mg x L(-1), respectively; SRF and moisture of sludge cake reduced to 2.02 x 10(8) s2 x g(-1) and 74.81%, respectively, showing good dewaterability of the treated sludge. Compared with the single use of PAC and PAM, the dual use of PAC and PAM showed the advantages of lower cost and better conditioning effect.

  1. Adaptation of the Activity Measure Post-Acute Care (AM-PAC) from English to Mandarin using the dual-panel translation approach.

    Science.gov (United States)

    Chang, Feng-Hang; Liou, Tsan-Hon; Brodersen, John; Comins, Jonathan D

    2017-06-23

    The aims of this study were to translate and adapt the Activity Measure Post-Acute Care (AM-PAC) from US English to Mandarin using the dual-panel method, and to assess its psychometric properties in an outpatient rehabilitation setting. The AM-PAC outpatient short forms were translated using the dual-panel method. The translated AM-PAC was tested in 550 Chinese-speaking rehabilitation outpatients. Floor and ceiling effects were evaluated and internal consistency was assessed using Cronbach's alpha. Spearman correlation was used to assess the concurrent validity of the AM-PAC with the Barthel Index and the Mini-Mental State Examination. Test-retest reliability was determined by administering the AM-PAC twice to 57 participants within a 2-7 day interval. Some ceiling effects (>20%) were observed in the Applied Cognition subscale. All subscales exhibited good internal consistency (α > 0.70). Supportive evidence for concurrent validity was found in strong correlations between Basic Mobility subscale and Barthel Index (r = 0.68), and Daily Activity subscale and Barthel Index (r = 0.70); and moderate correlations between Applied Cognition subscale and Mini-Mental State Examination (r = 0.50). Test-retest reliability for all subscales was high (intraclass correlation coefficient =0.89-0.98). The dual-panel approach was successfully used to translate the AM-PAC from English to Mandarin. Adequate reliability and validity in rehabilitation outpatients in Taiwan were established. Implications for Rehabilitation The dual-panel method is a modern translation technique, which was successfully used to adapt the Activity Measure Post-Acute Care from English to Mandarin. The Mandarin version of Activity Measure Post-Acute Care demonstrates adequate internal consistency, concurrent validity, and test-retest reliability in rehabilitation outpatients. The Activity Measure Post-Acute Care is superior to existing functional measures used to monitor activity

  2. Improved efficiency in clinical workflow of reporting measured oncology lesions via PACS-integrated lesion tracking tool.

    Science.gov (United States)

    Sevenster, Merlijn; Travis, Adam R; Ganesh, Rajiv K; Liu, Peng; Kose, Ursula; Peters, Joost; Chang, Paul J

    2015-03-01

    OBJECTIVE. Imaging provides evidence for the response to oncology treatment by the serial measurement of reference lesions. Unfortunately, the identification, comparison, measurement, and documentation of several reference lesions can be an inefficient process. We tested the hypothesis that optimized workflow orchestration and tight integration of a lesion tracking tool into the PACS and speech recognition system can result in improvements in oncologic lesion measurement efficiency. SUBJECTS AND METHODS. A lesion management tool tightly integrated into the PACS workflow was developed. We evaluated the effect of the use of the tool on measurement reporting time by means of a prospective time-motion study on 86 body CT examinations with 241 measureable oncologic lesions with four radiologists. RESULTS. Aggregated measurement reporting time per lesion was 11.64 seconds in standard workflow, 16.67 seconds if readers had to register measurements de novo, and 6.36 seconds for each subsequent follow-up study. Differences were statistically significant (p workflow-integrated lesion management tool, especially for patients with multiple follow-up examinations, reversing the onetime efficiency penalty at baseline registration.

  3. PARAFAC modeling of fluorescence excitation-emission spectra of fish bile for rapid en route screening of PAC exposure

    DEFF Research Database (Denmark)

    Christensen, Jan H.; Tomasi, Giorgio; Strand, Jakob

    2009-01-01

    . The EEMs were decomposed into a four-factor PARAFAC model. The comparison of the PARAFAC factors with the EEMs of PAC metabolites and amino acids suggests that two factors are related to PAC metabolites and two correspond to fluorescent residues of tryptophan and tyrosine in bile proteins. A new......Polycyclic aromatic compound (PAC) metabolites in fish bile can be used as biomarkers for recent environmental exposure to PACs. Here, a novel method for rapid screening of nonhydrolyzed fish bile is presented. The method is based on excitation-emission fluorescence spectroscopy combined...

  4. Fitoflagelados potencialmente tóxicos y nocivos de costas del Pacífico mexicano

    Directory of Open Access Journals (Sweden)

    Ernesto Bravo-Sierra

    2004-09-01

    Full Text Available Los fitoflagelados son un grupo heterogéneo de flagelados autotróficos, heterotróficos y mixotróficos, con importancia ecológica para los niveles tróficos en diferentes ecosistemas. Los fitoflagelados en costas del Pacífico mexicano (y en Latinoamérica en términos generales son virtualmente desconocidos, sólo se tienen pocos registros. El estudio de los fitoflagelados requiere de métodos complicados de recolección y análisis. Esta es, probablemente, la causa de la escasez de conocimiento de este grupo en áreas tropicales y subtropicales. Material recientemente recolectado a lo largo del Pacífico mexicano sirvió para el estudio de fitoflagelados marinos, incluyendo algunos tóxicos y potencialmente tóxicos. Se usaron muestras de plancton filtradas por gravedad y con bomba de vacío utilizando diferentes métodos de fijación y análisis. Se registran aquellas especies presentes o con posibilidad de estarlo que son potencialmente nocivas para el ecosistema marino pertenecientes a los Phyla Euglenophyta, Heterokontophyta y Haptophyta. Estas especies están distribuidas en el plancton, en aguas oceánicas y costerasThe phytoflagellates are a heterogeneous group of autotrophic, heterotrophic and mixothrophic flagellates of trophic importance in several ecosystems. As in the rest of Latin America, the phytoflagellates that occur in the Mexican Pacific coasts are virtually unknown except for a few records. Their study require complicated collection and analysis methods, a probable cause for the scarce knowledge of this group in tropical and subtropical areas. Material recently collected from various localities along the Mexican Pacific coasts was used to study phytoflagellates, including toxic and potentially toxic species. Plankton samples were treated by gravity and pump filtration, using different methods for fixation and analysis. The phyla Euglenophyta, Heterokontophyta and Haptophyta were found. They occur as plankton in oceanic

  5. Integration of PACS and HIS info the workflow of a nuclear medicine department. Experience in Regensburg

    International Nuclear Information System (INIS)

    Maenner, P.; Fuchs, E.; Marienhagen, J.; Schoenberger, J.; Eilles, C.; Tege, B.; Reicherzer, H.G.; Kurz, M.; Boerner, W.

    2006-01-01

    Aim: the development of new diagnostic techniques and the implementation of a modern quality control management system requires the continuous adaptation of existing data processing tools to the nuclear medicine diagnostic workflow. Furthermore, PACS connected to HIS facilitates and enhances the transfer of data and pictures, and satisfies the legal requirements for data retention as regulated by law. Therefore, the aim of this work is to present the architecture, structure and results of such a system newly installed in a department of nuclear medicine. Methods: initially, the nuclear medicine workflow was carefully analyzed and each step was correlated to the corresponding module. The standard SAP R/3 and IS-H / IS-H*med based software used for patient administration at the University of Regensburg Hospital was adapted to the needs of the Nuclear Medicine Department. The networking of the imaging systems was done by integration of a PACS. Finally, the PACS was connected to the HIS to allow the attachment of images to the medical report. Results, conclusion: by connecting the HIS to the nuclear medicine PACS, the workflow was significantly improved. The data management sequence starting at the reception desk, continuing through the nuclear medical examination, to the physician's final written and image report is clearly structured. Although high demands exist on technical support and administration the integration of PACS and HIS into the nuclear medicine workflow leads to enhanced efficiency and reduction in hospital costs. Patient and data management are considerably improved in this way. (orig.)

  6. Implementation of MINI-PACS using the DICOM converter on the Web

    International Nuclear Information System (INIS)

    Ji, Youn Sang

    2000-01-01

    In recent years, medical procedures have become more complex, while financial pressures for shortened hospital stays and increased efficiency in patient care have increased. As a result, several shortcomings of present film-based systems for managing medical images have become apparent. Maintaining film space is labor intensive and consumes valuable space. Because only single copies of radiological examinations exist, they are prone to being lost or misplaced, thereby consuming additional valuable time and expense. In this paper, MINI-PACS for image archiving, transmission, and viewing offers a solution to these problems. Proposed MINI-PACS consists of mainly four parts such as Web Module, Client-Server Module, Internal Module, Acquisition Module. In addition, MINI-PACS system includes DICOM Converter that Non-DICOM file format converts standard file format. In Client-Server Module case, Proposed system is combined both SCU(Service Class User: Client) part and SCP(Service Class Provider: Server) part therefore this system provides the high resolution image processing techniques based on windows platform. Because general PACS system is too expensive for Medium and Small hospitals to install and operate the full-PACS. Also, we constructed Web Module for database connection through the WWW.=20

  7. Effect of oxygen plasma treatment on adhesion improvement of Au deposited on Pa-c substrates

    International Nuclear Information System (INIS)

    Lee, Jeong Hoon; Hwang, Kyo Seon; Kim, Tae Song; Seong, Jin Wook; Yoon, Ki Hyun; Ahn, Sae Young

    2004-01-01

    Adhesion of gold on parylene C (Pa-c) is a major hurdle in achieving reliable and durable performance for biosensor application due to the hydrophobicity of Pa-c. It is, therefore, imperative to put efforts to improve adhesion between Au and Pa-c. In this reseach, oxygen plasma treatment for adhesion improvement was performed on Pa-c surfaces at various plasma powers and times. To analyze the relation of surface energy and roughness to adhesion promotion, we used several techniques such as contact-angle, surface-energy, surface-roughness, and adhesion analyses. As the oxygen plasma power and time were increased, the surface roughness of Pa-c increased. Also, Au films had larger and more uniform grain sizes as the oxygen plasma power and time were increased. Untreated surfaces revealed a contact angle of 108 .deg. , but the contact angle drastically decreased in the initial stage of oxygen plasma treatment and slowly decreased with increasing power and time to values of 27.3 and 34, respectively. From the adhesion analysis, adhesion was improved as the plasma power or time was increased. The improvement of adhesion is related to an increase in roughness as well as carbonyl groups.

  8. Development and practice for a PACS-based interactive teaching model for CT image

    International Nuclear Information System (INIS)

    Tian Junzhang; Jiang Guihua; Zheng Liyin; Wang Ling; Wenhua; Liang Lianbao

    2002-01-01

    Objective: To explore the interactive teaching model for CT imaging based on PACS, and provide the clinician and young radiologist with continued medical education. Methods: 100 M trunk net was adopted in PACS and 10 M was exchanged on desktop. Teaching model was installed in browse and diagnosis workstation. Teaching contents were classified according to region and managed according to branch model. Text data derived from authoritative textbooks, monograph, and periodicals. Imaging data derived from cases proved by pathology and clinic. The data were obtained through digital camera and scanner or from PACS. After edited and transformed into standard digital image through DICOM server, they were saved in HD of PACS image server with file form. Results: Teaching model for CT imaging provided kinds of cases of CT sign, clinic characteristics, pathology and distinguishing diagnosis. Normal section anatomy, typical image, and its notation could be browsed real time. Teaching model for CT imaging could provide reference to teaching, diagnosis and report. Conclusion: PACS-based teaching model for CT imaging could provide interactive teaching and scientific research tool and improve work quality and efficiency

  9. Study of pH-dependent drugs solubility in water

    Directory of Open Access Journals (Sweden)

    Pobudkowska A.

    2014-01-01

    Full Text Available The solubilities of five sparingly soluble drug-compounds in water have been measured at constant temperatures (298.1K and 310.1K by the classical saturation shake-flask method. All substances presented in this work are derivatives of anthranilic acid: flufenamic acid, (FLU, mefenamic acid, (MEF, niflumic acid, (NIF, diclofenac sodium, (DIC, and meclofenamic sodium, (MEC. All of them have anti-inflammatory action. Since the aqueous solubility of the ionized drug is significantly higher than the unionized, the experimental conditions that affect equilibrium solubility values such as composition of aqueous buffer have been examined. The Henderson-Hasselbalch (HH relationship has been used to predict the pH-dependent solubility profiles of chosen drugs at two temperatures. For this purpose the pKa values of the investigated drugs have been determined with Bates-Schwarzenbach spectrophotometric method at temperature 310.1 K. At temperature 298.1K these values were reported earlier. Similar values of pKa were obtained from the solubility measurements.

  10. Adoption and resistance: reflections on human, organizational, and information technologies in picture archive and communication systems (PACS)

    Science.gov (United States)

    Sappington, Rodney W.

    2005-04-01

    In research conducted at academic and community hospitals in the United States since 2001, this paper examines complex human and technological relationships employed to renegotiate behavior within hospital administrative and clinical cultures. In the planning and implementation of PACS in a four-facility hospital we will enter into what can be described as processes of "adoption" and "resistance", seemingly opposite approaches to system implementation, which I argue are in fact key responses to planning, design, and customization of imaging and information systems in a context of convergence. In a larger context of convergence known as NBIC tools (nanotechnology, biotechnology, information technology, and cognitive sciences) it has become increasingly clear to leaders in the field that it is essential to redesign organizational technologies. A novel system has little chance of being fully utilized by conventional organizational structures in an era of system convergence. The challenge of embracing a larger systems perspective lies in opening untapped potential within the healthcare enterprise by preparing the ground for reflection on new approaches to training, and bridging specialized knowledge across computer engineering, clinical decision making, and organizational perspectives for the benefit of patient care. Case studies will demonstrate how organizational and system design technologies are crucial in insuring that PACS implementation strategies can encourage the emergence of new levels of quality for patient care. The goal is to provide successful design-build models that are true to organizational specificity, persons, and clinical practices undergoing change and uncertainty.

  11. Evaluation of Picture Archiving and Communication System (Pacs As A Process Improvement Sample (Sivas Numune Hospital Application

    Directory of Open Access Journals (Sweden)

    Ali Rıza İnce

    2013-09-01

    Full Text Available It is a realitythatthefirmsproducinggoods or services frequentlybenefited process improvementand similartechniques toachieve their objectives In today'scompetitive environment.Beingprocess-orientedmeans to give weight to the creation of quality but not to the control of quality. In this sense, process improvement is seen as an approach of Total Quality Management targeted. Hospital informationsystems are computer systems that collect andarchive all orthe majority of the hospitaldatafor use inthe assessment.It isa major problem that storage of visualdatawithout lossanddamage and also the being availableof these data as soon as possiblein this system.System that calledPACShas been developedto overcome this problem.PACS is an archiving system that archive the visual dataobtained fromimaging systems in different unitsin a spaceand, allows the transfer of these data to usersat different points when needed.In this study,efficiency of PACS asa process improvementtechniquewas examined by the application ofahospital.It is concluded that the system providea positive contributionto customers and hospitalas an example ofan importantprocess improvement at the evaluationof the results and implementation of the system.

  12. Complete genome sequencing of the luminescent bacterium, Vibrio qinghaiensis sp. Q67 using PacBio technology

    Science.gov (United States)

    Gong, Liang; Wu, Yu; Jian, Qijie; Yin, Chunxiao; Li, Taotao; Gupta, Vijai Kumar; Duan, Xuewu; Jiang, Yueming

    2018-01-01

    Vibrio qinghaiensis sp.-Q67 (Vqin-Q67) is a freshwater luminescent bacterium that continuously emits blue-green light (485 nm). The bacterium has been widely used for detecting toxic contaminants. Here, we report the complete genome sequence of Vqin-Q67, obtained using third-generation PacBio sequencing technology. Continuous long reads were attained from three PacBio sequencing runs and reads >500 bp with a quality value of >0.75 were merged together into a single dataset. This resultant highly-contiguous de novo assembly has no genome gaps, and comprises two chromosomes with substantial genetic information, including protein-coding genes, non-coding RNA, transposon and gene islands. Our dataset can be useful as a comparative genome for evolution and speciation studies, as well as for the analysis of protein-coding gene families, the pathogenicity of different Vibrio species in fish, the evolution of non-coding RNA and transposon, and the regulation of gene expression in relation to the bioluminescence of Vqin-Q67.

  13. Effects of Nicotine Dependence and Depressive Symptoms on Smoking Cessation: A Longitudinal Study Among Adolescents

    NARCIS (Netherlands)

    Scherphof, C.S.; Eijnden, R.J.J.M. van den; Harakeh, Z.; Raaijmakers, Q.A.W.; Kleinjan, M.; Engels, R.C.M.E.; Vollebergh, W.A.M.

    2013-01-01

    Nicotine dependence has been shown to hamper successful smoking cessation in adolescents. Nicotine dependence and depression are highly comorbid, but the relation between depression and smoking cessation is not yet fully understood. Therefore, the present study examines both the longitudinal

  14. Study on temperature-dependent carrier transport for bilayer graphene

    Science.gov (United States)

    Liu, Yali; Li, Weilong; Qi, Mei; Li, Xiaojun; Zhou, Yixuan; Ren, Zhaoyu

    2015-05-01

    In order to investigate the temperature-dependent carrier transport property of the bilayer graphene, graphene films were synthesized on Cu foils by a home-built chemical vapor deposition (CVD) with C2H2. Samples regularity, transmittance (T) and layer number were analyzed by transmission electron microscope (TEM) images, transmittance spectra and Raman spectra. Van Der Pauw method was used for resistivity measurements and Hall measurements at different temperatures. The results indicated that the sheet resistance (Rs), carrier density (n), and mobility (μ) were 1096.20 Ω/sq, 0.75×1012 cm-2, and 7579.66 cm2 V-1 s-1 at room temperature, respectively. When the temperature increased from 0 °C to 240 °C, carrier density (n) increased from 0.66×1012 cm-2 to 1.55×1012 cm-2, sheet resistance (Rs) decreased from 1215.55 Ω/sq to 560.77 Ω/sq, and mobility (μ) oscillated around a constant value 7773.99 cm2 V-1 s-1. The decrease of the sheet resistance (Rs) indicated that the conductive capability of the bilayer graphene film increased with the temperature. The significant cause of the increase of carrier density (n) was the thermal activation of carriers from defects and unconscious doping states. Because the main influence on the carrier mobility (μ) was the lattice defect scattering and a small amount of impurity scattering, the carrier mobility (μ) was temperature-independent for the bilayer graphene.

  15. Diffusion-weighted MRI of the prostate at 3.0 T: comparison of endorectal coil (ERC) MRI and phased-array coil (PAC) MRI-The impact of SNR on ADC measurement.

    Science.gov (United States)

    Mazaheri, Yousef; Vargas, H Alberto; Nyman, Gregory; Shukla-Dave, Amita; Akin, Oguz; Hricak, Hedvig

    2013-10-01

    To compare ADC values measured from diffusion-weighted MR (DW-MR) images of the prostate obtained with both endorectal and phased-array coils (ERC+PAC) to those from DW-MRI images obtained with an eight-channel torso phased-array coil (PAC) at 3.0 T. The institutional review board issued a waiver of informed consent for this HIPAA-compliant study. Twenty-five patients with biopsy-proven prostate cancer underwent standard 3-T MRI using 2 different coil arrangements (ERC+PAC and PAC only) in the same session. DW-MRI at five b-values (0, 600, 1000, 1200, and 1500 s/mm(2)) were acquired using both coil arrangements. On b=0 images, signal-to-noise ratios (SNRs) were measured as the ratio of the mean signal from PZ and TZ ROIs to the standard deviation from the mean signal in an artifact-free ROI in the rectum. Matching regions-of-interest (ROIs) were identified in the peripheral zone and transition zone on ERC-MRI and PAC-MRI. For each ROI, mean ADC values for all zero and non-zero b-value combinations were computed. Mean SNR with ERC-MRI at PZ (66.33 ± 27.07) and TZ (32.69 ± 12.52) was 9.27 and 5.52 times higher than with PAC-MRI ((7.32 ± 2.30) and (6.13 ± 1.56), respectively) (PERC-MRI (PERC. To address these requirements, clinical MR systems should have image processing capabilities which incorporate the noise distribution. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  16. Judgments of learning depend on how learners interpret study effort.

    Science.gov (United States)

    Koriat, Asher; Nussinson, Ravit; Ackerman, Rakefet

    2014-11-01

    In self-paced learning, when the regulation of study effort is goal driven (e.g., allocated to different items according to their relative importance), judgments of learning (JOLs) increase with study time. When regulation is data driven (e.g., determined by the ease of committing the item to memory), JOLs decrease with study time (Koriat, Ma'ayan, & Nussinson, 2006). We induced learners to interpret differences in their study time (Experiment 1) or in another learner's study time (Experiment 2) as reflecting either differences in data-driven regulation or differences in goal-driven regulation. This manipulation was found to moderate the relationship of both study time and rated effort to JOLs. The results were seen to support the idea that JOLs are based on study effort but the effects of experienced effort are mediated by an attribution that intervenes between the metacognitive regulation of effort and the monitoring of one's learning. The results invite an attributional theoretical framework that encompasses both data-driven and goal-driven regulation and incorporates the option of attributing experienced effort to either or both of the 2 types of regulation. PsycINFO Database Record (c) 2014 APA, all rights reserved.

  17. Laboratory study of temperature dependence of creep of argillaceous rocks

    International Nuclear Information System (INIS)

    Boisson, J.Y.; Audiguier, M.; Billiotte, J.; Deveughele, M.; Norotte, V.

    1989-01-01

    The study deals with the evaluation of the long term effects of temperature variations on argillaceous soil structure and volume as a function of their initial petrophysical characteristics and their preconsolidation. From an experimental point of view, the study deals with the volumetric deformation of samples performed in oedometer apparatus at temperature between 20 0 C and 110 0 C and their permeability measurement. As an illustration of texture and mechanical behaviour study, the results of swelling, consolidation and creep of an argillaceous sample at 20 0 C are presented

  18. APPC - A new standardised coding system for trans-organisational PACS retrieval

    International Nuclear Information System (INIS)

    Fruehwald, F.; Lindner, A.; Mostbeck, G.; Hruby, W.; Fruehwald-Pallamar, J.

    2010-01-01

    As part of a general strategy to integrate the health care enterprise, Austria plans to connect the Picture Archiving and Communication Systems (PACS) of all radiological institutions into a nationwide network. To facilitate the search for relevant correlative imaging data in the PACS of different organisations, a coding system was compiled for all radiological procedures and necessary anatomical details. This code, called the Austrian PACS Procedure Code (APPC), was granted the status of a standard under HL7. Examples are provided of effective coding and filtering when searching for relevant imaging material using the APPC, as well as the planned process for future adjustments of the APPC. The implementation and how the APPC will fit into the future electronic environment, which will include an electronic health act for all citizens in Austria, are discussed. A comparison to other nationwide electronic health record projects and coding systems is given. Limitations and possible use in physical storage media are contemplated. (orig.)

  19. Application of Nano PAC on Mitigating Membrane Fouling by Surface Properties Optimization

    Directory of Open Access Journals (Sweden)

    Mi Hairong

    2016-01-01

    Full Text Available Membrane material has been widely accepted owing to the ability in water treatment, but the membrane fouling problem in using process is seriously restricted the promotion of membrane technology. So in this research nano PAC flocculant is added into the raw water to reach the goals of strengthening treatment efficiency and mitigating membrane fouling. According to the TMP change, it results that the PAC dosage of 45mg/L can realize the purpose to mitigate membrane fouling best. Compared with MBR, the MCBR is 16 days tardiness at the change of TMP, 1/3 gel layer filtration resistance less and 3.5% C element content fewer. The sum of C, O and N elements content, in addition, in the gel layer pollutants is more than 95%. That means membrane pollution is mainly caused by organic matter and nano PAC has the effect on surface properties optimization and membrane fouling mitigating.

  20. Implementation, reliability, and feasibility test of an Open-Source PACS.

    Science.gov (United States)

    Valeri, Gianluca; Zuccaccia, Matteo; Badaloni, Andrea; Ciriaci, Damiano; La Riccia, Luigi; Mazzoni, Giovanni; Maggi, Stefania; Giovagnoni, Andrea

    2015-12-01

    To implement a hardware and software system able to perform the major functions of an Open-Source PACS, and to analyze it in a simulated real-world environment. A small home network was implemented, and the Open-Source operating system Ubuntu 11.10 was installed in a laptop containing the Dcm4chee suite with the software devices needed. The Open-Source PACS implemented is compatible with Linux OS, Microsoft OS, and Mac OS X; furthermore, it was used with operating systems that guarantee the operation in portable devices (smartphone, tablet) Android and iOS. An OSS PACS is useful for making tutorials and workshops on post-processing techniques for educational and training purposes.

  1. Economic impact of an integrated RIS/PACS system in a university hospital

    International Nuclear Information System (INIS)

    Kroeger, M.; Wetekam, V.; Nissen-Meyer, S.; Reiser, M.

    1999-01-01

    Problem: The goal of the current article is to demonstrate how qualitative and monetary effects resulting from an integrated RIS/PACS installation can be evaluated. Results: The sample analysis of a RIS/PACS solution specially designed for a university hospital demonstrates positive qualitative and monetary effects of the system. Under ideal conditions the payoff time of the investments is reached after 4 years of an assumed 8 years effective life of the system. Furthermore, under conservative assumptions, the risk analysis shows a probability of 0% for realising a negative net present value at the end of the payoff time period. Conclusion: It should be pointed out that the positive result of this sample analysis will not necessarily apply to other clinics or hospitals. However, the same methods may be used for the individual evaluation of the qualitative and monetary effects of a RIS/PACS installation in any clinic. (orig.) [de

  2. Temperature dependent Dielectric studies of Poly(Ethylene Oxide)

    Science.gov (United States)

    Shiva Kumar, B. P.; Gurumurthy, T. M.; Praveen, D.

    2018-02-01

    Polymers are known to be better materials for dielectric applications. Various polymers with different molecular weights are being studied for dielectric applications. In the present paper, we report the dielectric measurements of Poly(Ethylene Oxide) {PEO} using Impedance spectroscopy studies. The dielectric studies of PEO were carried out on pellets as a function of temperature. It was found that the dielectric constant seems to be negligibly varying with increase in temperature at high frequencies, however, at low frequencies, dielectric constant varies increases with temperature. This may be due to the fact that with the thermal energy provided to the system, more and more dipoles participate and hence the net dielectric constant of the material is also higher at higher temperature. Also at very high frequencies, due to many non-responsive dipoles for fast switching of the applied signal, net dielectric constant of the material also does vary much with temperatures.

  3. A DFT study of temperature dependent dissociation mechanism of ...

    Indian Academy of Sciences (India)

    of HF in HF(H2O)7 cluster. SWATANTRA K YADAVa, HIRDYESH MISHRAa,∗ and ASHWANI K TIWARIb,∗ ... Dissociation constant, KRP, of HF dissociation and pKa values of HF in cluster at various temperatures have been reported. ... a series of studies on water cluster by means of graph theory and ab initio methods and ...

  4. A DFT study of temperature dependent dissociation mechanism of ...

    Indian Academy of Sciences (India)

    Abstract. We report a Density Functional Theoretical (DFT) study of dissociation of Hydrogen Fluoride (HF) in HF(H2O)7 cluster, using B3LYP functional and empirical exchange correlation functional M06-2X along with 6-31+G(d,p) basis set. Dissociation constant, KRP, of HF dissociation and pKa values of HF in cluster.

  5. Time-dependent micro-Raman scattering studies of polyvinyl ...

    Indian Academy of Sciences (India)

    2014-02-15

    Feb 15, 2014 ... Abstract. In-situ monitoring of silver nanoparticle formation was studied in thin films of poly- vinyl alcohol and silver nitrate. We proposed the observation of surface-enhanced Raman spec- troscopy (SERS) as a novel and simple technique to record the growth of silver nanoparticles in polyvinyl alcohol thin ...

  6. PACS for Bhutan: a cost effective open source architecture for emerging countries.

    Science.gov (United States)

    Ratib, Osman; Roduit, Nicolas; Nidup, Dechen; De Geer, Gerard; Rosset, Antoine; Geissbuhler, Antoine

    2016-10-01

    This paper reports the design and implementation of an innovative and cost-effective imaging management infrastructure suitable for radiology centres in emerging countries. It was implemented in the main referring hospital of Bhutan equipped with a CT, an MRI, digital radiology, and a suite of several ultrasound units. They lacked the necessary informatics infrastructure for image archiving and interpretation and needed a system for distribution of images to clinical wards. The solution developed for this project combines several open source software platforms in a robust and versatile archiving and communication system connected to analysis workstations equipped with a FDA-certified version of the highly popular Open-Source software. The whole system was implemented on standard off-the-shelf hardware. The system was installed in three days, and training of the radiologists as well as the technical and IT staff was provided onsite to ensure full ownership of the system by the local team. Radiologists were rapidly capable of reading and interpreting studies on the diagnostic workstations, which had a significant benefit on their workflow and ability to perform diagnostic tasks more efficiently. Furthermore, images were also made available to several clinical units on standard desktop computers through a web-based viewer. • Open source imaging informatics platforms can provide cost-effective alternatives for PACS • Robust and cost-effective open architecture can provide adequate solutions for emerging countries • Imaging informatics is often lacking in hospitals equipped with digital modalities.

  7. Thermomechanical analysis of solid breeders in sphere-pac, plate, and pellet configurations

    International Nuclear Information System (INIS)

    Blanchard, J.P.; Ghoniem, N.M.

    1986-02-01

    The first configuration studied is called sphere-pac. It features small breeder spheres of three different diameters, thus allowing efficient packing and minimal void fraction. The concept originated as an attempt to minimize thermal stresses in the breeder and improve the predictability of the breeder-structure interface heat conduction. In general the breeder is made as thin as possible, to maximize the breeding ratio, so the cladding's integrity will likely be the life-limiting issue of this concept. The third breeder configuration is in the form of pellets cladded by steel tubes. The major thermomechanical issue of the pin-type designs is cracking, which would impair the thermal performance of the blanket. Fortunately, the pins can be sized to prevent cracking under normal operation. In this report we have treated each blanket generically, dealing with basic issues rather than design specifics. Our basic philosophy is to avoid cracking of the breeder if at all possible. It can be argued that cracking could be allowed, but this would sacrifice predictability of the blanket thermal performance and tritium release characteristics. Proper design can and should minimize breeder cracking

  8. PAC characterization of Gd and Y doped nanostructured zirconia solid solutions

    Energy Technology Data Exchange (ETDEWEB)

    Caracoche, Maria C. [Facultad de Ciencias Exactas UNLP-IFLP and CICPBA (Argentina)]. E-mail: cristina@fisica.unlp.edu.ar; Martinez, Jorge A. [Facultad de Ciencias Exactas UNLP-IFLP and CICPBA (Argentina); Pasquevich, Alberto F. [Facultad de Ciencias Exactas UNLP-IFLP and CICPBA (Argentina); Rivas, Patricia C. [Facultad de Ciencias Agronomicas y Forestales UNLP-IFLP and CONICET (Argentina); Djurado, Elizabeth [INPG/CNRS, Cedex (France); Boulc' h, Florence [INPG/CNRS, Cedex (France)

    2007-02-01

    A perturbed angular correlation (PAC) study as a function of temperature has been carried out on spray pyrolysis-derived powders and compacts of 2.5 mol% Y{sub 2}O{sub 3}-ZrO{sub 2} and 2 mol% Gd{sub 2}O{sub 3}-ZrO{sub 2} nanostructured tetragonal zirconias. The powders undergo the ordinary thermal transformation between the two known defective t'- and regular t-tetragonal forms and also a partial and irreversible change to an ordered cubic configuration. The dynamical nature of the t'-form leads to an activation energy of about 0.15 eV for the oxygen vacancies movement. The as-obtained compacts do not exhibit any known cubic nanostructure but some additional contributions. In both of them a hyperfine component assigned to the orthorhombic phase is determined. In the smaller cation Y doped ceramic a small amount of monoclinic phase reflects an incomplete stabilization.

  9. Size dependent studies of metal nanoparticles with bio-fluorophores

    Science.gov (United States)

    Patil, Ajeetkumar; Ballary, Steffy; George, Sajan D.; Chidangil, Santhosh

    2017-06-01

    Interaction of noble metal nanoparticles (NPs) with fluorophores has been an important research area in the field of material science and biomedical field. In the proximity of a metal nanoparticle, there is a quenching or enhancement in the intrinsic fluorescence of the fluorophore . The conditional quenching of the fluorescence can be used for negative sensing whereas enhancement in the fluorescence can be used to gain greater sensitivity and high signal to noise ratio in the molecular sensing/imaging. The current work deals with the systematic studies to understand the fluorescence quenching for few bio-fluorophores (NADH and FAD) when interacted with different sized silver nano-particles of (10nm, 40nm and 100nm). Home assembled Laser Induced Fluorescence (LIF) set-up was used to study the fluorescence quenching of NADH and FAD for different sized silver nanoparticles.

  10. Intereses nacionales convergentes en una apuesta colectiva: la alianza del pacífico

    OpenAIRE

    Escobar Onofre, Francisco Javier

    2016-01-01

    Este documento indaga sobre los determinantes que hicieron posible la creación de la Alianza del Pacífico. Para ello, se describen elementos del contexto internacional y regional dentro del cual se gestó la Alianza, y que permitió la convergencia de unos intereses afines entre Chile, Colombia, Perú y México que, determinados por identidades similares, desembocaron en un proyecto colectivo: La Alianza del Pacífico. El argumento principal es que los intereses, las características y las identida...

  11. Estado del Medio Ambiente Marino y Costero del Pacífico Sudeste.

    OpenAIRE

    Andrade V., Héctor; Guitiérres S., Sixto; Andrade C., Héctor

    2014-01-01

    El presente documento contiene los antecedentes sistematizados sobre el Estado del Medio Ambiente Marino Costero del Pacífico Sudeste en base a los informes nacionales de consultoría elaborados entre 2011 y 2012 en Panamá, Colombia, Ecuador, Perú y Chile y cuya finalidad fue establecer un estado actualizado del medio marino a nivel regional, en el marco del Programa CONPACSE III de la Comisión Permanente de Pacífico Sur. Los principales contaminantes presentes en las aguas marinas costeras de...

  12. Shape-dependent designability studies of lattice proteins

    International Nuclear Information System (INIS)

    Peto, Myron; Kloczkowski, Andrzej; Jernigan, Robert L

    2007-01-01

    One important problem in computational structural biology is protein designability, that is, why protein sequences are not random strings of amino acids but instead show regular patterns that encode protein structures. Many previous studies that have attempted to solve the problem have relied upon reduced models of proteins. In particular, the 2D square and the 3D cubic lattices together with reduced amino acid alphabet models have been examined extensively and have led to interesting results that shed some light on the evolutionary relationship among proteins. Here we perform designability studies on the 2D square lattice and explore the effects of variable overall shapes on protein designability using a binary hydrophobic-polar (HP) amino acid alphabet. Because we rely on a simple energy function that counts the total number of H-H interactions between non-sequential residues, we restrict our studies to protein shapes that have the same number of residues and also a constant number of non-bonded contacts. We have found that there is a marked difference in the designability between various protein shapes, with some of them accounting for a significantly larger share of the total foldable sequences

  13. Report of the collaboration project for research and development of sphere-pac fuel among JNC-PSI-NRG (1). Planning, fuel design, pin fabrication

    International Nuclear Information System (INIS)

    Morihira, Masayuki; Ozawa, Takayuki; Tomita, Yutaka; Suzuki, Masahiro; Kihara, Yoshiyuki; Shigetome, Yoshiaki; Kohno, Shusaku

    2004-07-01

    The collaboration project concerning sphere-pac fuel among JNC, Swiss PSI (Paul Scherrer Institut) and Dutch NRG (Nuclear Research and Consultancy Group) is in progress. Final target of the project is comparative irradiation tests of sphere-pac fuel in the HFR (High Flux Reactor) in Petten in the Netherlands with pellet type fuel and vipack fuel. Total 16 fuel segments (8 pins) of these three types of fuel are planned to be irradiated. Two sphere-pac fuel segments contain 5%Np in addition to 20%Pu-MOX. Other segments contain no Np. The objective of the irradiation tests is to obtain the restructuring data in the early beginning of life for SPF as well as power-to-melt test data for the potential study of SPF. At the same time introduction of modeling technique for irradiation performance analysis, fuel design, fuel fabrication is also important objective for JNC. Fabrication of irradiation test pins was completed till May 2003 in PSI. After transportation of the fuel pins to Petten, two times of irradiation were performed in January to March in 2004 and now post irradiation tests are in progress. Later two irradiations will be done till the autumn in 2004. This report summarized the basic plan, fuel design, and fabrication of irradiation test pins concerning this collaboration project. (author)

  14. Removal of APIs and bacteria from hospital wastewater by MBR plus O(3), O(3) + H(2)O(2), PAC or ClO(2).

    Science.gov (United States)

    Nielsen, U; Hastrup, C; Klausen, M M; Pedersen, B M; Kristensen, G H; Jansen, J L C; Bak, S N; Tuerk, J

    2013-01-01

    The objective of this study has been to develop technologies that can reduce the content of active pharmaceutical ingredients (APIs) and bacteria from hospital wastewater. The results from the laboratory- and pilot-scale testings showed that efficient removal of the vast majority of APIs could be achieved by a membrane bioreactor (MBR) followed by ozone, ozone + hydrogen peroxide or powdered activated carbon (PAC). Chlorine dioxide (ClO(2)) was significantly less effective. MBR + PAC (450 mg/l) was the most efficient technology, while the most cost-efficient technology was MBR + ozone (156 mg O(3)/l applied over 20 min). With MBR an efficient removal of Escherichia coli and enterococci was measured, and no antibiotic resistant bacteria were detected in the effluent. With MBR + ozone and MBR + PAC also the measured effluent concentrations of APIs (e.g. ciprofloxacin, sulfamethoxazole and sulfamethizole) were below available predicted no-effect concentrations (PNEC) for the marine environment without dilution. Iodinated contrast media were also reduced significantly (80-99% for iohexol, iopromide and ioversol and 40-99% for amidotrizoateacid). A full-scale MBR treatment plant with ozone at a hospital with 900 beds is estimated to require an investment cost of €1.6 mill. and an operating cost of €1/m(3) of treated water.

  15. Inhomogeneous broadening of PAC spectra with Vzz and η joint probability distribution functions

    International Nuclear Information System (INIS)

    Evenson, W. E.; Adams, M.; Bunker, A.; Hodges, J.; Matheson, P.; Park, T.; Stufflebeam, M.; Zacate, M. O.

    2013-01-01

    The perturbed angular correlation (PAC) spectrum, G 2 (t), is broadened by the presence of randomly distributed defects in crystals due to a distribution of electric field gradients (EFGs) experienced by probe nuclei. Heuristic approaches to fitting spectra that exhibit such inhomogeneous broadening (ihb) consider only the distribution of EFG magnitudes V zz , but the physical effect actually depends on the joint probability distribution function (pdf) of V zz and EFG asymmetry parameter η. The difficulty in determining the joint pdf leads us to more appropriate representations of the EFG coordinates, and to express the joint pdf as the product of two approximately independent pdfs describing each coordinate separately. We have pursued this case in detail using as an initial illustration of the method a simple point defect model with nuclear spin I = 5/2 in several cubic lattices, where G 2 (t) is primarily induced by a defect trapped in the first neighbor shell of a probe and broadening is due to defects distributed at random outside the first neighbor shell. Effects such as lattice relaxation are ignored in this simple test of the method. The simplicity of our model is suitable for gaining insight into ihb with more than V zz alone. We simulate ihb in this simple case by averaging the net EFGs of 20,000 random defect arrangements, resulting in a broadened average G 2 (t). The 20,000 random cases provide a distribution of EFG components which are first transformed to Czjzek coordinates and then further into the full Czjzek half plane by conformal mapping. The topology of this transformed space yields an approximately separable joint pdf for the EFG components. We then fit the nearly independent pdfs and reconstruct G 2 (t) as a function of defect concentration. We report results for distributions of defects on simple cubic, face-centered cubic, and body-centered cubic lattices. The method explored here for analyzing ihb is applicable to more realistic cases.

  16. Inhomogeneous broadening of PAC spectra with V zz and η joint probability distribution functions

    Science.gov (United States)

    Evenson, W. E.; Adams, M.; Bunker, A.; Hodges, J.; Matheson, P.; Park, T.; Stufflebeam, M.; Zacate, M. O.

    2013-05-01

    The perturbed angular correlation (PAC) spectrum, G 2( t), is broadened by the presence of randomly distributed defects in crystals due to a distribution of electric field gradients (EFGs) experienced by probe nuclei. Heuristic approaches to fitting spectra that exhibit such inhomogeneous broadening (ihb) consider only the distribution of EFG magnitudes V zz , but the physical effect actually depends on the joint probability distribution function (pdf) of V zz and EFG asymmetry parameter η. The difficulty in determining the joint pdf leads us to more appropriate representations of the EFG coordinates, and to express the joint pdf as the product of two approximately independent pdfs describing each coordinate separately. We have pursued this case in detail using as an initial illustration of the method a simple point defect model with nuclear spin I = 5/2 in several cubic lattices, where G 2( t) is primarily induced by a defect trapped in the first neighbor shell of a probe and broadening is due to defects distributed at random outside the first neighbor shell. Effects such as lattice relaxation are ignored in this simple test of the method. The simplicity of our model is suitable for gaining insight into ihb with more than V zz alone. We simulate ihb in this simple case by averaging the net EFGs of 20,000 random defect arrangements, resulting in a broadened average G 2( t). The 20,000 random cases provide a distribution of EFG components which are first transformed to Czjzek coordinates and then further into the full Czjzek half plane by conformal mapping. The topology of this transformed space yields an approximately separable joint pdf for the EFG components. We then fit the nearly independent pdfs and reconstruct G 2( t) as a function of defect concentration. We report results for distributions of defects on simple cubic, face-centered cubic, and body-centered cubic lattices. The method explored here for analyzing ihb is applicable to more realistic cases.

  17. CASE STUDY ON RE-ADJUSTMENTS DEPENDING ON PRICE MODIFICATION

    Directory of Open Access Journals (Sweden)

    Cozma Ighian Diana

    2011-01-01

    Full Text Available Inflationary moments, characterized by significant price rises, have proved that accountingsystems based on historical costs provide a distorted image of the reality: the elements ofthe balance sheet are under-valuated, and the stock-related expenses and amortization in theprofit and loss account are also under-valuated. Under these circumstances, the result isover-valuated, and its distribution leads to allotments from the company’s capital. In thispaper we draw up a case study with regards to the methods used for adjusting pricemodification, clearly outlining, through a comparative analysis, the main differencesbetween the accounting system based on historical cost and inflation accounting.

  18. Polyubiquitinated proteins, proteasome, and glycogen characterize the particle-rich cytoplasmic structure (PaCS) of neoplastic and fetal cells.

    Science.gov (United States)

    Necchi, Vittorio; Sommi, Patrizia; Vitali, Agostina; Vanoli, Alessandro; Savoia, Anna; Ricci, Vittorio; Solcia, Enrico

    2014-05-01

    A particle-rich cytoplasmic structure (PaCS) concentrating ubiquitin-proteasome system (UPS) components and barrel-like particles in clear, cytoskeleton- and organelle-free areas has recently been described in some neoplasms and in genetic or infectious diseases at risk of neoplasia. Ultrastructurally similar particulate cytoplasmic structures, interpreted as glycogen deposits, have previously been reported in clear-cell neoplasms and some fetal tissues. It remains to be investigated whether the two structures are the same, colocalize UPS components and polysaccharides, and have a role in highly proliferative cells such as fetal and neoplastic cells. We used immunogold electron microscopy and confocal immunofluorescence microscopy to examine human and mouse fetal tissues and human neoplasms. Fetal and neoplastic cells both showed colocalization of polyubiquitinated proteins, 19S and 20S proteasomes, and polysaccharides, both glycogen and chondroitin sulfate, inside cytoplasmic structures showing all distinctive features of PaCSs. Poorly demarcated and/or hybrid (ribosomes admixed) UPS- and glycogen-enriched areas, likely stages in PaCS development, were also seen in some fetal cells, with special reference to those, like primary alveolar pulmonary cells or pancreatic centroacinar cells, having a crucial role in organogenesis. UPS- and glycogen-rich PaCSs developed extensively in clear-cell neoplasms of the kidney, ovary, pancreas, and other organs, as well as, in infantile, development-related tumors replicating fetal patterns, such as choroid plexus papilloma. UPS-mediated, ATP-dependent proteolysis and its potential energy source, glycogen metabolism, may have a crucial, synergic role in embryo-/organogenesis and carcinogenesis.

  19. Study of Dependencies in Executions of E-Contract Activities

    Science.gov (United States)

    Vidyasankar, K.; Krishna, P. Radha; Karlapalem, Kamalakar

    An e-contract is a contract modeled, specified, executed, controlled and monitored by a software system. A contract is a legal agreement involving parties, activities, clauses and payments. The goals of an e-contract include precise specification of the activities of the contract, mapping them into deployable workflows, and providing transactional support in their execution. Activities in a contract are generally complex and interdependent. They may be executed by different parties autonomously and in a loosely coupled fashion. They differ from database transactions in many ways: (i) Different successful executions are possible for an activity; (ii) Unsuccessful executions may be compensated or re-executed to get different results; (iii) Whether an execution is successful or not may not be known until after several subsequent activities are executed, and so it may be compensated and/or re-executed at different times relative to the execution of other activities; (iv) Compensation or re-execution of an activity may require compensation or re-execution of several other activities; etc. In this paper, we study the interdependencies between the executions of e-contract activities. This study will be helpful in monitoring behavioral conditions stated in an e-contracts during its execution.

  20. Water Balance Study of a Groundwater-dependent Oak Forest

    Directory of Open Access Journals (Sweden)

    MÓRICZ, Norbert

    2010-01-01

    Full Text Available The objectives of this study were (1 to estimate the water balance components of an oak standby calibrating a Hydrus 1-D model, (2 to determine the groundwater consumption by the water tablefluctuation method and (3 to compare the results of the modelling with a remote-sensing based estimation.Model simulation described the observed soil moisture and groundwater level relatively well, theroot mean square errors varied between 12.0 and 14.9% for the soil moisture measurements and 5.0%for the groundwater level. Groundwater consumption was estimated also by the water table fluctuationmethod, which provided slightly different groundwater consumption rates than estimated by theHydrus model simulation. The simulated evapotranspiration was compared with results of a remotesensingbased estimation using the surface temperature database of MODIS.According to the Hydrus model, the estimated evapotranspiration resulted from transpiration(73%, interception loss (23% and soil surface evaporation (4% in the two-year study period. Theproportion of groundwater consumption was 58% of the total transpiration. During the dry growingseason of 2007 the groundwater consumption was significant with 66% of the total transpiration.Water supply from groundwater was found to be less important in the wet growing season of 2008with 50%. The remote-sensing based estimation of evapotranspiration was about 4% lower than themodel based results of nearby comparable sites.

  1. Picture archiving and communication systems (PACS) in clinical practice. Implantacion de un sistema de archivo y comunicacion de imagen (PACS) en la practica clinica

    Energy Technology Data Exchange (ETDEWEB)

    Carreo Pedemonte, J.C.; Piqueras Pardellans, J.; Lucaya Layret, J.

    1994-01-01

    Picture archiving and communication systems (PACS) were developed as a technological response to the complex management of the growing amount of information generated by the different diagnostic imaging methods. This article documents the process of the progressive implementation, starting in January 1991, of the first complete PACS installed in our country. The system installed in our center is composed of acquisition modules for all the imaging methods (computed radiography, ultrasound, computed tomography, digital fluoroscopy and magnetic resonance), a central processing unit, an automatic optical disk for storage and a network of image viewing and diagnostic stations. The preliminary results obtained with its implementation demonstrate that PACS provide a series of functional advantages, especially at the image storage and display levels. In spite of these conveniences, the present high costs of acquisition and maintenance, together with certain technical problems as a result of its complexity, will signify that its generalized application for all imaging methods will not become a reality at most centers in the near future. (Author)

  2. Radial dependence of foreshock cavities: a case study

    Directory of Open Access Journals (Sweden)

    D. G. Sibeck

    2004-12-01

    Full Text Available We present a case study of Geotail, Interball-1, IMP-8, and Wind observations of density and magnetic field strength cavities excavated by the enhanced pressures associated with bursts of energetic ions in the foreshock. Consistent with theoretical predictions, the pressure of the energetic ions diminishes rapidly with upstream distance due to a decrease in the flux of energetic ions and a transition from near-isotropic to streaming pitch angle distributions. Consequently, the cavities can only be observed immediately upstream from the bow shock. A comparison of conditions upstream from the pre- and post-noon bow shock demonstrates that foreshock cavities introduce perturbations into the oncoming solar wind flow with dimensions smaller than those of the magnetosphere. Dayside geosynchronous magnetic field strength variations observed by GOES-8 do not track the density variations seen by any of the spacecraft upstream from the bow shock in a one-to-one manner, indicating that none of these spacecraft observed the precise sequence of density variations that actually struck the subsolar magnetopause. Key words. Interplanetary physics (energetic particles; planetary bow shocks – Magnetospheric physics (solar wind-magnetosphere interactions

  3. Spin dependence studies with the ZGS polarized proton beam

    International Nuclear Information System (INIS)

    Wicklund, A.B.

    1977-01-01

    Selected results are summarized of recent measurements using a polarized proton beam at the Argonne ZGS. The polarized target asymmetry and the beam-target spin correlation are measured in pp→pp at 6 and 12 GeV/c. Asymmetry is slowly varying with energy while spin correlation increases considerably from 6 to 12 GeV/c. The polarized parameters in pp→pp and pn→pn elastic scattering are compared. The data show that pp and pn polarizations tend to approach mirror symmetry as the energy increases. The effective mass spectrometer has been used to study the pp→pπ + n, pn→pπ - p reactions from 2 to 6 GeV/c. For small -t values (-t 2 ) these reactions are dominated by π exchange. At large -t values other mechanisms besides π-exchange become important. The 3-body diffraction dissociation reactions have been measured at 6 GeV/c with hydrogen and deuterium targets. The reactions are pp→pπ + π - (p); pd→pπ + π - (p+n). Comparison of hydrogen and deuterium cross section reveals a considerable coherent contribution of deuterium, which has an approximately 20% larger cross section per nucleon than hydrogen

  4. Combined targeting of EGFR-dependent and VEGF-dependent pathways: rationale, preclinical studies and clinical applications.

    Science.gov (United States)

    Tortora, Giampaolo; Ciardiello, Fortunato; Gasparini, Giampietro

    2008-09-01

    Cellular heterogeneity, redundancy of molecular pathways and effects of the microenvironment contribute to the survival, motility and metastasis of cells in solid tumors. It is unlikely that tumors are entirely dependent on only one abnormally activated signaling pathway; consequently, treatment with an agent that interferes with a single target may be insufficient. Combined blockade of functionally linked and relevant multiple targets has become an attractive therapeutic strategy. The EGFR and ERBB2 (HER2) pathways and VEGF-dependent angiogenesis have a pivotal role in cancer pathogenesis and progression. Robust experimental evidence has shown that these pathways are functionally linked and has demonstrated a suggested role for VEGF in the acquired resistance to anti-ERBB drugs when these receptors are pharmacologically blocked. Combined inhibition of ERBB and VEGF signaling interferes with a molecular feedback loop responsible for acquired resistance to anti-ERBB agents and promotes apoptosis while ablating tumor-induced angiogenesis. To this aim, either two agents highly selective against VEGF and ERBB respectively, or, alternatively, a single multitargeted agent, can be used. Preclinical studies have proven the efficacy of both these approaches and early clinical studies have provided encouraging results. This Review discusses the experimental rationale for, preclinical studies of and clinical trials on combined blockade of ERBB and VEGF signaling.

  5. Investigation of small scale sphere-pac fuel fabrication plant with external gelation process

    International Nuclear Information System (INIS)

    Maekawa, Kazuhiko; Yoshimura, Tadahiro; Kikuchi, Toshiaki; Hoshino, Yasushi; Munekata, Hideki; Shimizu, Makoto

    2005-02-01

    In feasibility studies on commercialized FBR cycle system, comprehensive system investigation and properties evaluation for candidate FBR cycle systems have been implemented through view point of safety, economics, environmental burden reduction, non-proliferation resistivity, etc. As part of these studies, an investigation of small scale sphere-pac fuel fabrication plant with external gelation process was conducted. Until last fiscal year, equipment layout in cells and overall layout design of the 200t-HM/y scale fuel fabrication plant were conducted as well as schematical design studies on main equipments in gelation and reagent recovery processes of the plant. System property data concerning economics and environmental burden reduction of fuel fabrication plant was also acquired. In this fiscal year, the processes from vibropacking to fuel assemblies storage were added to the investigation range, and a conceptual design of whole fuel fabrication plant was studied as well as deepening the design study on main equipments. The conceptual design study was mainly conducted for small 50t-HM/y scale plant and a revising investigation was done for 200t-HM/y scale plant. Taking the planed comparative evaluation with pellet fuel fabrication system into account, design of equipments which should be equivalent with pellet system, especially in post-vibropacking processes, were standardized in each system. Based on these design studies, system properties data concerning economics and environmental burden reduction of the plant was also acquired. In comparison with existing design, the cell height was lowered on condition that plug type pneumatic system was adopted and fuel fabrication building was downsized by applying rationalized layout design of pellet system to post-vibropacking processes. Reduction of reagent usage at gelation process and rationalization of sintering and O/M controlling processes etc., are foremost tasks. (author)

  6. Traffic and trend analysis of local- and wide-area networks for a distributed PACS implementation

    Science.gov (United States)

    Gac, Robert J., Jr.; Harding, Douglas, Jr.; Weiser, John C.; Chacko, Anna K.; Radvany, Martin; Romlein, John R.

    2000-05-01

    Inductive Modeling Techniques (IMT) in a stand alone, distributed Picture Archiving and Communication System (PACS) or telemedicine environment can be utilized to monitor SNMP (Simple Network Management Protocol) enabled devices such as network switches, servers or workstations. A comprehensive approach using IMT is presented across the stages of the PACS lifecycle: Pre-PACS, Implementation, and Clinical Use. At each stage of the cycle, the results of IMT can be utilized to assist in assessing and forecasting future system loading. This loading represents a clinical trend analysis equating to the clinical workflow and delivery of services. Specific attention is directed to an understanding and thorough depiction of IMT methodology, focusing on the use of SNMP, the Management Information Base (MIB), and the data stream output that is mapped and placed in an object-oriented database and made available for web-based, real time, in-depth viewing and/or analysis. A thorough description of these outputs is presented, spotlighting potential report applications such as system failures; existing system, CPU, workstation, server and LAN/WAN link utilization; packet rates; application isolation; notification of system alarms; fault isolation; high/low bandwidth users; and data transfer rates. These types of data are increasingly required for programming LAN/WAN upgrades as digital imaging and PACS are implemented.

  7. Modification of human beta-globin locus PAC clones by homologous recombination in Escherichia coli

    NARCIS (Netherlands)

    G.P. Patrinos (George); M. de Krom (Mariken); S. Bottardi; R.J. Janssens; E. Katsantoni (Eleni); A.W. Wai; D.J. Sherratt; F.G. Grosveld (Frank); A.M.A. Imam (Ali)

    2000-01-01

    textabstractWe report here modifications of human beta-globin PAC clones by homologous recombination in Escherichia coli DH10B, utilising a plasmid temperature sensitive for replication, the recA gene and a wild-type copy of the rpsL gene which allows for an efficient selection for

  8. 75 FR 55777 - Pro-Pac Distributing Corp., Provisional Acceptance of a Settlement Agreement and Order

    Science.gov (United States)

    2010-09-14

    ...; telephone (301) 504-7733. SUPPLEMENTARY INFORMATION: The text of the Agreement and Order appears below... sweatshirts with drawstrings at the neck, in sizes Youth S-L (collectively, ``Sweatshirts''). 5. Pro-Pac sold... (``Guidelines'') to help prevent children from strangling or entangling on neck and waist drawstrings. The...

  9. Integration of radiology and hospital information systems (RIS, HIS) with PACS: requirements of the radiologist.

    Science.gov (United States)

    Mosser, H; Urban, M; Dürr, M; Rüger, W; Hruby, W

    1992-12-01

    PACS development has now reached a stage where it can clearly be stated that the technology for storage, networking and display in a fully digital environment is available. This is reflected by an already large and rapidly increasing number of PACS installations in USA, Western Europe and Japan. Such installations consist of a great variety of information systems, more or less interconnected, like PACS, HIS, RIS and other departmental systems, differing in both hardware and software. Various data - even if they only concern one person - are stored in different systems distributed in the hospital. The integration of all digital systems into a functional unit is determined by the radiologist's need of quick access to all relevant information regardless where it is stored. The interconnection and functional integration of all digital systems in the hospital determine the clinical benefits of PACS. This paper (1) describes the radiologist's requirements concerning this integration, and (2) presents some realistic solutions such as the Siemens ISI (Information System Interface), and a mobile viewing station for the wards (visitBox).

  10. From international charity to value chain coordinator : The case of the Pueblos en Accion Comunitaria (PAC)

    NARCIS (Netherlands)

    G.M. Gómez (Georgina)

    2011-01-01

    markdownabstractThis article describes the activities of The association Pueblos en Acción Comunitaria (PAC) as a model of value chain organization with an entrepreneurial vision and Christian inspiration and enquires in what ways it represents a new model to promote local development and poverty

  11. Communication of Unexpected and Significant Findings on Chest Radiographs With an Automated PACS Alert System.

    LENUS (Irish Health Repository)

    Hayes, Sara A

    2014-08-01

    An integral part of realizing the enormous potential of imaging in patient care is close communication between radiologists and referring physicians. One key element of this process is the communication of unexpected significant findings. The authors examined the performance of a PACS-based alert system in the appropriate communication of reports containing unexpected significant findings to referring physicians.

  12. Enterprise-wide PACS: beyond radiology, an architecture to manage all medical images.

    Science.gov (United States)

    Bandon, David; Lovis, Christian; Geissbühler, Antoine; Vallée, Jean-Paul

    2005-08-01

    Picture archiving and communication systems (PACS) have the vocation to manage all medical images acquired within the hospital. To address the various situations encountered in the imaging specialties, the traditional architecture used for the radiology department has to evolve. We present our preliminarily results toward an enterprise-wide PACS intended to support all kind of image production in medicine, from biomolecular images to whole-body pictures. Our solution is based on an existing radiologic PACS system from which images are distributed through an electronic patient record to all care facilities. This platform is enriched with a flexible integration framework supporting digital image communication in medicine (DICOM) and DICOM-XML formats. In addition, a generic workflow engine highly customizable is used to drive work processes. Echocardiology; hematology; ear, nose, and throat; and dermatology, including wounds, follow-up is the first implemented extensions outside of radiology. We also propose a global strategy for further developments based on three possible architectures for an enterprise-wide PACS.

  13. Integration of radiology and hospital information systems (RIS, HIS) with PACS

    International Nuclear Information System (INIS)

    Mosser, H.; Urban, M.; Hruby, W.; Duerr, M.; Rueger, W.

    1992-01-01

    PACS development has now reached a stage where it can clearly be stated that the technology for storage, networking and display in a fully digital environment is available. This is reflected by an already large and rapidly increasing number of PACS installations in USA, Western Europe and Japan. Such installations consist of a great variety of information systems, more or less interconnected, like PACS, HIS, RIS and other departmental systems, differing in both hardware and software. Various data -even if they only concern one person- are stored in different systems distributed in the hospital. The integration of all digital systems into a functional unit is determined by the radiologist's need of quick access to all relevant information regardless where it is stored. The interconnection and functional integration of all digital systems in the hospital determine the clinical benefits of PACS. This paper describes the radiologist's requirements concerning this integration, and presents some realistic solutions such as the Siemens ISI (Information System Interface), and a mobile viewing station for the wards (visitBox). (author). 9 refs., 4 figs

  14. Pacéré as the demiurge of orature | Kaboré | Tydskrif vir letterkunde

    African Journals Online (AJOL)

    The implications of the genre of orature are manifold. Orature calls for a redefinition of literature as whatever a given society considers as literature. It demands an interpretation of literature based on an understanding of culture. Keywords: Orature, written and spoken literatures, F. T. Pacéré. > Tydskrif vir Letterkunde Vol.

  15. 75 FR 80082 - State, Local, Tribal, And Private Sector Policy Advisory Committee (SLTPS-PAC)

    Science.gov (United States)

    2010-12-21

    ... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Information Security Oversight Office State, Local, Tribal, And Private Sector Policy Advisory Committee (SLTPS-PAC) AGENCY: Information Security Oversight... 41 CFR 101-6, the Information Security Oversight Office (ISOO) announces the inaugural meeting of the...

  16. 77 FR 41204 - State, Local, Tribal, and Private Sector Policy Advisory Committee (SLTPS-PAC)

    Science.gov (United States)

    2012-07-12

    ... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Information Security Oversight Office State, Local, Tribal, and Private Sector Policy Advisory Committee (SLTPS-PAC) AGENCY: Information Security Oversight..., announcement is made for the committee meeting of the State, Local, Tribal, and Private Sector Policy Advisory...

  17. EST-PAC a web package for EST annotation and protein sequence prediction

    Directory of Open Access Journals (Sweden)

    Strahm Yvan

    2006-10-01

    Full Text Available Abstract With the decreasing cost of DNA sequencing technology and the vast diversity of biological resources, researchers increasingly face the basic challenge of annotating a larger number of expressed sequences tags (EST from a variety of species. This typically consists of a series of repetitive tasks, which should be automated and easy to use. The results of these annotation tasks need to be stored and organized in a consistent way. All these operations should be self-installing, platform independent, easy to customize and amenable to using distributed bioinformatics resources available on the Internet. In order to address these issues, we present EST-PAC a web oriented multi-platform software package for expressed sequences tag (EST annotation. EST-PAC provides a solution for the administration of EST and protein sequence annotations accessible through a web interface. Three aspects of EST annotation are automated: 1 searching local or remote biological databases for sequence similarities using Blast services, 2 predicting protein coding sequence from EST data and, 3 annotating predicted protein sequences with functional domain predictions. In practice, EST-PAC integrates the BLASTALL suite, EST-Scan2 and HMMER in a relational database system accessible through a simple web interface. EST-PAC also takes advantage of the relational database to allow consistent storage, powerful queries of results and, management of the annotation process. The system allows users to customize annotation strategies and provides an open-source data-management environment for research and education in bioinformatics.

  18. PACS: Do clinical users benefit from it as a training adjunct? | van ...

    African Journals Online (AJOL)

    Background. Over the past four years, Steve Biko Academic Hospital has been in the process of implementing and refining the use of a picture archiving and communications system (PACS). As part of a post-implementation refining process, it was necessary to evaluate user-perceptions in order to improve on good system ...

  19. La inserción al Asia-Pacífico, oportunidades y desafíos para el Valle del Cauca y la región pacífica colombiana

    Directory of Open Access Journals (Sweden)

    Ricardo Coutin

    2014-12-01

    Full Text Available Resumen: El objetivo general del texto es brindar una aproximación a los retos y las oportunidades que representa, para el Valle del Cauca y la Región Pacífica colombiana, la inserción al Asia-Pacífico. Para lo cual se plantean tres objetivos específicos: primero, analizar someramente el contexto económico comercial del Asia-Pacífico y América Latina, con especial énfasis en Colombia y los demás países de la Alianza del Pacífico (AP; segundo, estudiar las oportunidades y los retos para el Valle del Cauca y la Región Pacífica colombiana que plantea la puesta en escena del bloque comercial denominado Alianza del Pacífico; y tercero, indagar sobre los retos de competitividad y productividad que enfrenta el Valle del Cauca y que afectan el ambiente de negocios. El documento concluye que Colombia se encuentra rezagada en su inserción con la cuenca del Asia-Pacífico; también se plantea la necesidad de abordar el tema de estudio desde un enfoque subnacional.

  20. High In Vitro Antibacterial Activity of Pac-525 against Porphyromonas gingivalis Biofilms Cultured on Titanium

    Directory of Open Access Journals (Sweden)

    Ji-yin Li

    2015-01-01

    Full Text Available In order to investigate the potential of short antimicrobial peptides (AMPs as alternative antibacterial agents during the treatment of peri-implantitis, the cytotoxic activity of three short AMPs, that is, Pac-525, KSL-W, and KSL, was determined using the MTT assay. The antimicrobial activity of these AMPs, ranging in concentration from 0.0039 mg/mL to 0.5 mg/mL, against the predominant planktonic pathogens, including Streptococcus sanguis, Fusobacterium nucleatum, and Porphyromonas gingivalis, involved in peri-implantitis was investigated. Furthermore, 2-day-old P. gingivalis biofilms cultured on titanium surfaces were treated with Pac-525 and subsequently observed and analysed using confocal laser scanning microscopy (CLSM. The average cell proliferation curve indicated that there was no cytotoxicity due to the three short AMPs. The minimum inhibitory concentration and minimum bactericidal concentration values of Pac-525 were 0.0625 mg/mL and 0.125 mg/mL, respectively, for P. gingivalis and 0.0078 mg/mL and 0.0156 mg/mL, respectively, for F. nucleatum. Using CLSM, we confirmed that compared to 0.1% chlorhexidine, 0.5 mg/mL of Pac-525 caused a significant decrease in biofilm thickness and a decline in the percentage of live bacteria. These data indicate that Pac-525 has unique properties that might make it suitable for the inhibition the growth of pathogenic bacteria around dental implants.

  1. Remote consultation and diagnosis in medical imaging using a global PACS backbone network

    Science.gov (United States)

    Martinez, Ralph; Sutaria, Bijal N.; Kim, Jinman; Nam, Jiseung

    1993-10-01

    A Global PACS is a national network which interconnects several PACS networks at medical and hospital complexes using a national backbone network. A Global PACS environment enables new and beneficial operations between radiologists and physicians, when they are located in different geographical locations. One operation allows the radiologist to view the same image folder at both Local and Remote sites so that a diagnosis can be performed. The paper describes the user interface, database management, and network communication software which has been developed in the Computer Engineering Research Laboratory and Radiology Research Laboratory. Specifically, a design for a file management system in a distributed environment is presented. In the remote consultation and diagnosis operation, a set of images is requested from the database archive system and sent to the Local and Remote workstation sites on the Global PACS network. Viewing the same images, the radiologists use pointing overlay commands, or frames to point out features on the images. Each workstation transfers these frames, to the other workstation, so that an interactive session for diagnosis takes place. In this phase, we use fixed frames and variable size frames, used to outline an object. The data pockets for these frames traverses the national backbone in real-time. We accomplish this feature by using TCP/IP protocol sockets for communications. The remote consultation and diagnosis operation has been tested in real-time between the University Medical Center and the Bowman Gray School of Medicine at Wake Forest University, over the Internet. In this paper, we show the feasibility of the operation in a Global PACS environment. Future improvements to the system will include real-time voice and interactive compressed video scenarios.

  2. Treatment of system dependencies and human interactions in PRA studies: a review and sensitivity study

    International Nuclear Information System (INIS)

    Orvis, D.D.; Joksimovich, V.; Worledge, D.H.

    1985-01-01

    The Electric Power Research Institute sponsored the review and comparison of five PRA studies: Arkansas Nuclear One - Unit 1, Big Rock Point, Grand Gulf, Limerick, and Zion - Unit 1. The review has been conducted in two phases. The Phase I review may be characterized as a qualitative look into many aspects of a PRA study. The Phase II review was performed to quantify the extent that differences in analytical techniques or key assumptions in these areas affect the differences in study results. In each of the PRA studies reviewed, the general descriptions of analytical approaches and descriptions of the analyses of event tree, fault tree and human interaction analyses that affected the dominant core damage sequences were reviewed. When these descriptions aroused interest because of seeming inconsistencies within the study or with other studies, they were pursued in some depth. The approaches or assumptions were contrasted to similar elements from other studies, and sensitivity analyses were performed in many cases to test the significance of results to the analytical models or assumptions. Inferences were drawn from the results regarding significance of the item to plant-specific results and, where possible, were generalized to other PRAs. This paper describes the results of the review of system dependencies and human interactions

  3. Limitaciones y fortalezas de la integración latinoamericana. Una visión desde las iniciativas del arco del pacífico latinoamericano y el acuerdo del pacífico. Periodo: 2007 - 2011

    OpenAIRE

    García Pérez, Juan Sebastián

    2012-01-01

    En la actualidad el Pacífico es visto como un espacio de oportunidades para aprovechar, bien sea de manera individual o a través de la creación de iniciativas comunes que conduzcan a mayores acercamientos a esta región. Si se apela a las iniciativas, es preciso estudiar el Acuerdo del Pacífico – AP, un espacio conformado por México, Colombia, Perú y Chile, que se plantea como principal objetivo el acercamiento a la región de Asia – Pacífico. Así, el presente documento intenta hacer un aporte ...

  4. The guarantee of the consistency of patient information through modality worklist among PACS, RIS and imaging equipments

    International Nuclear Information System (INIS)

    Luo Min; Peng Chenglin; Wang Xiaolin; Luo Song; Lei Wenyong; Wang Kang; Wang Xuejian; Wen Hongyu; Wu Hongxing

    2003-01-01

    Objective: To realize the consistency of patient information through modality worklist among picture archiving and communication system (PACS), radiology information systems (RIS), and imaging equipments. Methods: Many digital modalities including GE Signa 1.5 T MR system, digital mammography, Agfa digital radiography, computed radiography, GE CT, and etc were installed in our hospital. Since the GE PACS system was in English version, the images were saved and the information was managed to PACS without a truly worklist. Two months later, while still using the previous PACS, the consistency of patient information was resolved through modality worklist by adopting the international advanced approach to realize thread worklist of digital imaging and communication in medicine. The information in Chinese will be transformed into information in English in RIS system and saved as the English information to worklist. Results: After the implementation and integration of PACS and RIS was achieved in my hospital, the consistency of patient information was guaranteed through modality worklist between RIS and imaging equipments and the first-rate effect was acquired. The patient information could be checked, edited, and created by using the Chinese RIS system on all diagnostic workstations. Conclusion: The consistency of patient information through modality worklist was realized among PACS, RIS, and imaging equipments, yet at present, the question of guarantee the consistency of patient information must be thought over in PACS building

  5. Pulmonary Artery Catheter (PAC Accuracy and Efficacy Compared with Flow Probe and Transcutaneous Doppler (USCOM: An Ovine Cardiac Output Validation

    Directory of Open Access Journals (Sweden)

    Robert A. Phillips

    2012-01-01

    Full Text Available Background. The pulmonary artery catheter (PAC is an accepted clinical method of measuring cardiac output (CO despite no prior validation. The ultrasonic cardiac output monitor (USCOM is a noninvasive alternative to PAC using Doppler ultrasound (CW. We compared PAC and USCOM CO measurements against a gold standard, the aortic flow probe (FP, in sheep at varying outputs. Methods. Ten conscious sheep, with implanted FPs, had measurements of CO by FP, USCOM, and PAC, at rest and during intervention with inotropes and vasopressors. Results. CO measurements by FP, PAC, and USCOM were 4.0±1.2 L/min, 4.8±1.5 L/min, and 4.0±1.4 L/min, respectively, (=280, range 1.9 L/min to 11.7 L/min. Percentage bias and precision between FP and PAC, and FP and USCOM was −17 and 47%, and 1 and 36%, respectively. PAC under-measured Dobutamine-induced CO changes by 20% (relative 66% compared with FP, while USCOM measures varied from FP by 3% (relative 10%. PAC reliably detected −30% but not +40% CO changes, as measured by receiver operating characteristic area under the curve (AUC, while USCOM reliably detected ±5% changes in CO (AUC>0.70. Conclusions. PAC demonstrated poor accuracy and sensitivity as a measure of CO. USCOM provided equivalent measurements to FP across a sixfold range of outputs, reliably detecting ±5% changes.

  6. Integrating RIS/PACS: the web-based solution at University Hospital of Ribeirão Preto, Brazil.

    Science.gov (United States)

    de Azevedo-Marques, Paulo Mazzoncini; Caritá, Edilson Carlos; Benedicto, Alexander Antonio; Sanches, Pablo Rodrigo

    2004-09-01

    Integration of a Radiology Information System (RIS) and a Picture Archiving and Communication System (PACS) reduces the risk of inconsistent data by reducing interfaces among databases that contain largely redundant information. Furthermore, RIS/PACS integration is the basis for a filmless radiology facility. Web technology is based on international standards and supplies the main features for the RIS/PACS integration task based on a client/server model. This article presents a web-based system developed to manage and distribute images and diagnostic information within the University Hospital of Ribeirão Preto (HCRP) at the University of Sao Paulo.

  7. PACS for Bhutan: a cost effective open source architecture for emerging countries

    Directory of Open Access Journals (Sweden)

    Osman Ratib

    2016-07-01

    Full Text Available Abstract This paper reports the design and implementation of an innovative and cost-effective imaging management infrastructure suitable for radiology centres in emerging countries. It was implemented in the main referring hospital of Bhutan equipped with a CT, an MRI, digital radiology, and a suite of several ultrasound units. They lacked the necessary informatics infrastructure for image archiving and interpretation and needed a system for distribution of images to clinical wards. The solution developed for this project combines several open source software platforms in a robust and versatile archiving and communication system connected to analysis workstations equipped with a FDA-certified version of the highly popular Open-Source software. The whole system was implemented on standard off-the-shelf hardware. The system was installed in three days, and training of the radiologists as well as the technical and IT staff was provided onsite to ensure full ownership of the system by the local team. Radiologists were rapidly capable of reading and interpreting studies on the diagnostic workstations, which had a significant benefit on their workflow and ability to perform diagnostic tasks more efficiently. Furthermore, images were also made available to several clinical units on standard desktop computers through a web-based viewer. Messages/teaching points • Open source imaging informatics platforms can provide cost-effective alternatives for PACS • Robust and cost-effective open architecture can provide adequate solutions for emerging countries • Imaging informatics is often lacking in hospitals equipped with digital modalities

  8. Change in Care Dependency of Stroke Patients: A Longitudinal and Multicenter Study

    Directory of Open Access Journals (Sweden)

    Nursiswati Nursiswati, MN

    2017-06-01

    Conclusions: Based on the findings of this study, we recommend that hospital-based and community-based services should include continual care dependence monitoring using this comprehensive instrument. Care dependency is subject to change over time, therefore nurses have to plan and tailor adequate nursing care measures to patient needs in the different stages, especially with respect to the aspect of mobility.

  9. [PACS: from project to reality. Report of experiences on full digitalisation of the radiology department of a major hospital].

    Science.gov (United States)

    Gross-Fengels, W; Miedeck, C; Siemens, P; Appel, R; Mückner, K; Finsterbusch, J; Bonas, H

    2002-02-01

    To assess the time needed and the resulting effects of a complete digitalisation of a radiological department of a major hospital (856 beds, 28,000 in-patients, 35,000 out-patients/year) a pilot study was performed. This had to be done without interrupting routine services. After intensive preparations were performed and the hospital-network was completed, within a two year period all radiological functions (mammography excluded), reporting stations and archives were changed to a complete digital workflow. All modalities (provided by 3 different companies) are now connected by DICOM-work lists. The picture-files (4 GB/day) are automatically routed to the work-stations (n = 10), where the reporting and file shows are performed, to the digital archive and to the peripheral viewing-stations (n = 44). The distribution of the digital pictures takes place all over the hospital including the ORs and special units. We accomplished, to connect electronically the report and the image data. The clinical file shows are also performed completely digitally. The access to the data of the deep archive is possible by the dept. of radiology without any manual interaction. The film consumption was reduced to an amount of less than 10%, as compared to the prior PACS situation. Since PACS has been introduced the radiological productivity increased by more than 15% and throughput-time was clearly reduced. The complete digitalisation increases productivity and attractiveness of a hospital-radiology and helps to shorten diagnostic and therapeutic decision-making. The transfer from a conventional to a digital workflow is possible without interrupting the clinical services. Extensive preparations and ongoing assistance of such projects though are clearly needed.

  10. A cross-sectional study on tobacco use and dependence among women: Does menthol matter?

    Science.gov (United States)

    Rosenbloom, Judith; Rees, Vaughan W; Reid, Kathleen; Wong, Jeannie; Kinnunen, Taru

    2012-11-27

    The question of whether mentholation of cigarettes enhances tobacco dependence has generated conflicting findings. Potential mediating factors in a putative relationship between menthol use and tobacco dependence may include race and gender. While an association between menthol use and dependence is mixed, research on the role of race solely among women smokers is scarce. This study examined whether women menthol smokers have higher tobacco use and dependence than non-menthol smokers. Further, the study investigated differences between White and African American smokers. A cross-sectional study was conducted among 928 women seeking tobacco dependence treatment in Boston, Massachusetts. Measures obtained included preferred brand and menthol content, dependence markers (cigarettes per day (CPD); time to first cigarette in the morning; number of and longest previous quit attempts) and smoking history (age of initiation; years smoking; menthol or non-menthol cigarette preference). Analysis of variance (ANOVA) was used to detect interactions between menthol preference by race for continuous variables, and Pearson's chi-squared test was used for analyses with dichotomous variables. A greater proportion of menthol smokers smoked their first cigarette within five minutes of waking (p preferences. However, African American smokers smoked fewer CPD (pbrand for longer (p= .04). Women menthol smokers showed signs of greater tobacco dependence than non-menthol smokers. African Americans smoked fewer CPD but nevertheless had evidence of greater dependence.

  11. A cross-sectional study on tobacco use and dependence among women: Does menthol matter?

    Directory of Open Access Journals (Sweden)

    Rosenbloom Judith

    2012-11-01

    Full Text Available Abstract Background The question of whether mentholation of cigarettes enhances tobacco dependence has generated conflicting findings. Potential mediating factors in a putative relationship between menthol use and tobacco dependence may include race and gender. While an association between menthol use and dependence is mixed, research on the role of race solely among women smokers is scarce. This study examined whether women menthol smokers have higher tobacco use and dependence than non-menthol smokers. Further, the study investigated differences between White and African American smokers. Methods A cross-sectional study was conducted among 928 women seeking tobacco dependence treatment in Boston, Massachusetts. Measures obtained included preferred brand and menthol content, dependence markers (cigarettes per day (CPD; time to first cigarette in the morning; number of and longest previous quit attempts and smoking history (age of initiation; years smoking; menthol or non-menthol cigarette preference. Analysis of variance (ANOVA was used to detect interactions between menthol preference by race for continuous variables, and Pearson’s chi-squared test was used for analyses with dichotomous variables. Results A greater proportion of menthol smokers smoked their first cigarette within five minutes of waking (p Conclusions Women menthol smokers showed signs of greater tobacco dependence than non-menthol smokers. African Americans smoked fewer CPD but nevertheless had evidence of greater dependence.

  12. One-year study of polycyclic aromatic compounds at an urban site in Grenoble (France): Seasonal variations, gas/particle partitioning and cancer risk estimation

    Energy Technology Data Exchange (ETDEWEB)

    Tomaz, Sophie [Institut National de l' Environnement industriel et des RISques (INERIS), Parc Technologique Alata BP2, 60550 Verneuil en Halatte (France); CNRS, EPOC, UMR 5805, F-33405 Talence Cedex (France); Université de Bordeaux, EPOC, UMR 5805, F-33405, Talence Cedex (France); Shahpoury, Pourya [Max Planck Institute for Chemistry, Multiphase Chemistry Department, Mainz (Germany); Jaffrezo, Jean-Luc [Laboratoire de Glaciologie et Géophysiques de l' Environnement (LGGE), Université de Grenoble-Alpes/CNRS, Grenoble (France); Lammel, Gerhard [Max Planck Institute for Chemistry, Multiphase Chemistry Department, Mainz (Germany); Masaryk University, Research Centre for Toxic Compounds in the Environment, Brno (Czech Republic); Perraudin, Emilie; Villenave, Eric [CNRS, EPOC, UMR 5805, F-33405 Talence Cedex (France); Université de Bordeaux, EPOC, UMR 5805, F-33405, Talence Cedex (France); Albinet, Alexandre, E-mail: alexandre.albinet@gmail.com [Institut National de l' Environnement industriel et des RISques (INERIS), Parc Technologique Alata BP2, 60550 Verneuil en Halatte (France)

    2016-09-15

    21 PAHs, 27 oxy-PAHs and 32 nitro-PAHs were measured every third day over a year in both gaseous (G) and particulate PM{sub 10} (P) phases in ambient air of Grenoble (France). Mean total concentrations (G + P) of PAHs and oxy-PAHs were in the same range and about 10 ng m{sup −3}. Nitro-PAHs were 50 to 100 times less concentrated averaging 100 pg m{sup −3}. Polycyclic aromatic compound (PAC) concentrations were 5 to 7 times higher in “cold” period (October to March) than in “warm” period (April to September). Seasonal variations may be explained by higher primary emissions from residential heating, especially biomass burning in “cold” season. Meteorological conditions and influence of the geomorphology around Grenoble, with the formation of thermal inversion layers leading to the stagnation of pollutants, were additional key parameters. Maximum individual PAC concentrations were observed during two PM{sub 10} pollution events in December and February–March. Chemical processes and secondary formation of oxy- and nitro-PAH were probably enhanced by the accumulation of the pollutants during these events. PAC gas/particle partitioning depended on compound molecular weight and vapour pressure. Gas/particle partitioning of oxy- and nitro-PAHs were evaluated using a multi-phase poly-parameter linear free energy relationship model. The PAC cancer risk was assessed using toxic equivalency factors available in the literature (19 PAHs, 10 nitro-PAHs and 1 oxy-PAH). Overall, particle-bound PACs contributed about 76% of the cancer risk. While PAHs accounted for most of the total PAC cancer risk, oxy- and nitro-PAHs could account for up to 24%. The risk quantification across substance classes is limited by toxicological data availability. - Highlights: • The most comprehensive study about PAH, nitro- and oxy-PAH in ambient air. • 80 species studied in gaseous and particle phases over a year at French urban site. • Concentration seasonality governed by

  13. La inserción al Asia-Pacífico, oportunidades y desafíos para el Valle del Cauca y la región pacífica colombiana

    OpenAIRE

    Ricardo Coutin

    2014-01-01

    Resumen: El objetivo general del texto es brindar una aproximación a los retos y las oportunidades que representa, para el Valle del Cauca y la Región Pacífica colombiana, la inserción al Asia-Pacífico. Para lo cual se plantean tres objetivos específicos: primero, analizar someramente el contexto económico comercial del Asia-Pacífico y América Latina, con especial énfasis en Colombia y los demás países de la Alianza del Pacífico (AP); segundo, estudiar las oportunidades y los retos para el Va...

  14. La inserción al Asia-Pacífico, oportunidades y desafíos para el Valle del Cauca y la región pacífica colombiana

    OpenAIRE

    Countin, Ricardo

    2014-01-01

    El objetivo general del texto es brindar una aproximación a los retos y las oportunidades que representa, para el Valle del Cauca y la Región Pacífica colombiana, la inserción al Asia-Pacífico. Para lo cual se plantean tres objetivos específicos: primero, analizar someramente el contexto económico comercial del Asia-Pacífico y América Latina, con especial énfasis en Colombia y los demás países de la Alianza del Pacífico (AP); segundo, estudiar las oportunidades y los retos para el Valle del C...

  15. Inhomogeneous broadening of PAC spectra with V{sub zz} and {eta} joint probability distribution functions

    Energy Technology Data Exchange (ETDEWEB)

    Evenson, W. E.; Adams, M.; Bunker, A.; Hodges, J.; Matheson, P.; Park, T.; Stufflebeam, M. [Utah Valley University, Department of Physics (United States); Zacate, M. O., E-mail: zacatem1@nku.edu [Northern Kentucky University, Department of Physics and Geology (United States)

    2013-05-15

    The perturbed angular correlation (PAC) spectrum, G{sub 2}(t), is broadened by the presence of randomly distributed defects in crystals due to a distribution of electric field gradients (EFGs) experienced by probe nuclei. Heuristic approaches to fitting spectra that exhibit such inhomogeneous broadening (ihb) consider only the distribution of EFG magnitudes V{sub zz}, but the physical effect actually depends on the joint probability distribution function (pdf) of V{sub zz} and EFG asymmetry parameter {eta}. The difficulty in determining the joint pdf leads us to more appropriate representations of the EFG coordinates, and to express the joint pdf as the product of two approximately independent pdfs describing each coordinate separately. We have pursued this case in detail using as an initial illustration of the method a simple point defect model with nuclear spin I = 5/2 in several cubic lattices, where G{sub 2}(t) is primarily induced by a defect trapped in the first neighbor shell of a probe and broadening is due to defects distributed at random outside the first neighbor shell. Effects such as lattice relaxation are ignored in this simple test of the method. The simplicity of our model is suitable for gaining insight into ihb with more than V{sub zz} alone. We simulate ihb in this simple case by averaging the net EFGs of 20,000 random defect arrangements, resulting in a broadened average G{sub 2}(t). The 20,000 random cases provide a distribution of EFG components which are first transformed to Czjzek coordinates and then further into the full Czjzek half plane by conformal mapping. The topology of this transformed space yields an approximately separable joint pdf for the EFG components. We then fit the nearly independent pdfs and reconstruct G{sub 2}(t) as a function of defect concentration. We report results for distributions of defects on simple cubic, face-centered cubic, and body-centered cubic lattices. The method explored here for analyzing ihb is

  16. The influence of occupational stress factors on the nicotine dependence: a cross sectional study

    Directory of Open Access Journals (Sweden)

    Wolf Jürgen

    2010-04-01

    Full Text Available Abstract Objective This study analyses the association between occupational stress factors and nicotine dependence. Our hypothesis is that occupational stress factors increase nicotine dependence. Methods Data were taken from the Cologne Smoking Study, a case-control study that examines which genetic/psychosocial factors lead to a higher risk for smokers to suffer from cardiac infarction, lung cancer and/or to become addicted to nicotine. Our sample consisted of N = 197 currently smoking and employed participants. Nicotine dependence was measured using the Fagerström Test for Nicotine Dependence (FTND. The extent of the stress factors experienced at work was assessed using the Effort-Reward Imbalance scale (ERI. Logistic regression was used for the statistical analysis. Results Contrary to our hypothesis, the results show that occupational stress factors are actually associated with lower levels of nicotine dependence (N = 197; adjusted OR = 0.439; p = .059. Conclusions One possible explanation for the study's findings is that the participants have a heavy workload and can only smoke in their spare time. Another reason may be workplace smoking bans. Furthermore, the Fagerström Test for Nicotine Dependence is unable to examine nicotine dependence during working hours.

  17. Análisis Comparativo de Reglas de Origen en la Alianza Pacífico y en los TLC de los Países Miembros

    Directory of Open Access Journals (Sweden)

    José Roberto Concha V.

    2016-01-01

    Full Text Available El objetivo de este trabajo es comparar las reglas de origen entre el acuerdo de integración regional Alianza del Pacífico y los tratados de libre comercio de Colombia con Chile, la CAN y el G3, con el propósito de determinar si existen diferencias significativas entre estos. En el transcurso de la investigación, se encontró que sí existen diferencias en las reglas de origen entre estos acuerdos comerciales, que pueden generar incentivos al exportador para elegir un acuerdo en específico. La principal conclusión, es que no siempre la mejor opción para exportar a Chile, México o Perú es a través de la Alianza del Pacífico, como se esperaría siendo este el acuerdo pactado más reciente. La elección del acuerdo depende de la mercancía a exportar, por lo cual se recomienda buscar antes la subpartida arancelaria y analizar por cuál tratado sería más beneficioso hacerlo, de acuerdo a sus características y composición.

  18. Estimation of dose to the unborn child at diagnostic X-ray examinations based on data registered in RIS/PACS

    International Nuclear Information System (INIS)

    Helmrot, Ebba; Pettersson, Haakan; Sandborg, Michael; Alten, Jonas Nilsson

    2007-01-01

    The aim of this work was to determine mean absorbed doses to the unborn child in common conventional X-ray and computed tomography (CT) examinations and to find an approach for estimating foetal dose based on data registered in the Radiological Information System/Picture Archive and Communication System (RIS/PACS). The kerma-area product (KAP) and CT dose index (CTDI vol ) in common examinations were registered using a human-shaped female dosimetry phantom. Foetal doses, D f , were measured using thermoluminescent dosimeters placed inside the phantom and compared with calculated values. Measured foetal doses were given in relation to the KAP and the CTDI vol values, respectively. Conversion factor D f /KAP varies between 0.01 and 3.8 mGy/Gycm 2 , depending on primary beam position, foetus age and beam quality (tube voltage and filtration). Conversion factors D f /CTDI vol are in the range 0.02 - 1.2 mGy/mGy, in which the foetus is outside or within the primary beam. We conclude that dose conversion factors based on KAP or CTDI vol values automatically generated by the RIS/PACS system can be used for rapid estimations of foetal dose for common examination techniques. (orig.)

  19. Parceria Trans-Pacífico: Novas Geometrias no Capitalismo Global

    OpenAIRE

    Lins, Hoyêdo Nunes

    2014-01-01

    Em 2005, Brunei, Chile, Cingapura e Nova Zelândia firmaram acordo de parceria econômica no sentido de uma interação estratégica na região Ásia-Pacífico. Em 2009, os Estados Unidos se envolveram, assumindo a liderança das negociações. Desde então, as tratativas sobre a Parceria Trans-Pacífico ganharam impulso, com Austrália, Malásia, Peru e Vietnã aderindo em 2010 e Canadá e México em 2012, somando onze membros até o início de 2013. Baseado em pesquisa bibliográfica e documental, o artigo cara...

  20. Development of Cryogenic Filter Wheels for the HERSCHEL Photodetector Array Camera & Spectrometer (PACS)

    Science.gov (United States)

    Koerner, Christian; Kampf, Dirk; Poglitsch, Albrecht; Schubert, Josef; Ruppert, U.; Schoele, M.

    2014-01-01

    This paper describes the two PACS Filter Wheels that are direct-drive rotational mechanisms operated at a temperature below 5K inside the PACS focal plane unit of the Herschel Satellite. The purpose of the mechanisms is to switch between filters. The rotation axis is pivoted to the support structure via a slightly preloaded pair of ball bearings and driven by a Cryotorquer. Position sensing is realized by a pair of Hall effect sensors. Powerless positioning at the filter positions is achieved by a magnetic ratchet system. The key technologies are the Cryotorquer design and the magnetic ratchet design in the low temperature range. Furthermore, we will report on lessons learned during the development and qualification of the mechanism and the paint.

  1. Phase quantification of mullite-zirconia and zircon commercial powders using PAC and XRD techniques

    Energy Technology Data Exchange (ETDEWEB)

    Rendtorff, Nicolas M.; Conconi, Maria S.; Aglietti, Esteban F. [Centro de Tecnologia de Recursos Minerales y Ceramica (CETMIC: CONICET-CIC) (Argentina); Chain, Cecilia Y.; Pasquevich, Alberto F. [Universidad Nacional de La Plata, Departamento de Fisica, IFLP, Facultad de Ciencias Exactas (Argentina); Rivas, Patricia C. [CONICET (Argentina); Martinez, Jorge A., E-mail: toto@fisica.unlp.edu.ar; Caracoche, Maria C. [Universidad Nacional de La Plata, Departamento de Fisica, IFLP, Facultad de Ciencias Exactas (Argentina)

    2010-06-15

    The short range technique of the Perturbed Angular Correlation (PAC) and x-ray diffraction (Rietveld) methods have been employed to determine the phase content in commercial mullite-zirconia and zircon raw materials that are ordinarily used to produce ceramic materials. The PAC technique, which probes zirconium-containing compounds at nanoscopic level, showed that zircon contains crystalline ZrSiO{sub 4} and an important amount of a structurally distorted zircon, which is also observed accompanying monoclinic zirconia in mullite-zirconia. This particular zircon phase was not detected by the long range x-ray diffraction-Rietveld technique. After an annealing treatment, important changes in crystalline contents of the powders allow confirming, by the x-ray diffraction-Rietveld method, the preexistence of this particular zircon phase. This fact must be taken into account when preparing multicomposites based on the present raw materials.

  2. Perturbed Angular Correlation (PAC)/NMR spectroscopic properties and dynamics of compounds containing metal ions

    DEFF Research Database (Denmark)

    Arcisauskaité, Vaida

    in proteins: • ZORA-4/BH&H for 199mHg PAC spectroscopic properties, • ZORA/BH&HLYP for 199Hg NMR spectroscopic properties. By using these methods we further examined in Section 6.5 the influence of the immediate crystal environment on these spectroscopic properties and concluded that it does matter, in some......199mHg PAC and 199Hg NMR spectroscopic properties, nuclear quadrupole coupling constants, Q, asymmetry parameters, , and chemical shifts, , respectively, are the fingerprint of the local molecular and electronic structure, at the probed Hg nuclei. For this reason, these spectroscopic techniques...... have been used to elucidate Hg coordination in proteins. Computational chemistry calculations have a potential to contribute to the interpretation of this spectroscopic data, as calculated diagonalised electric field gradient (EFG) tensor components (jVzzj jVyyj jVxxj) and NMR shielding constants...

  3. The Radar Correlation and Interpolation (C&I) Algorithms Deployed in the ASR-9 Processor Augmentation Card (9PAC)

    National Research Council Canada - National Science Library

    Elkin, G

    2001-01-01

    .... The increased processing speed and memory size of the 9PAC hardware made it possible for new surveillance algorithms to be developed in software in order to provide improved primary radar and beacon...

  4. Using an open-source PACS virtual machine for a digital angiography unit: methods and initial impressions.

    Science.gov (United States)

    Kagadis, George C; Alexakos, Christos; Langer, Steve G; French, Todd

    2012-02-01

    The productivity gains, diagnostic benefit, and enhanced data availability to clinicians enabled by picture archiving and communication systems (PACS) are no longer in doubt. However, commercial PACS offerings are often extremely expensive initially and require ongoing support contracts with vendors to maintain them. Recently, several open-source offerings have become available that put PACS within reach of more users. However, they can be resource-intensive to install and assure that they have room for future growth--both for computational and storage capacity. An alternate approach, which we describe herein, is to use PACS built on virtual machines which can be moved from smaller to larger hardware as needed in a just-in-time manner. This leverages the cost benefits of Moore's Law for both storage and compute costs. We describe the approach and current results in this paper.

  5. New Methods for Landslide Identification and Mapping Using SAR Polarimetry Obtained During the PacRim 2000 Mission in Taiwan

    National Research Council Canada - National Science Library

    Czuchlewski, Kristina R; Weissel, Jeffrey K; Lee, Jong-Sen

    2005-01-01

    We reanalyze PacRim 2000 L-band AIRSAR polarimetry collected over the western foothills of central Taiwan a year after the September 20, 1999 ChiChi earthquake, which produced more than 10,000 landslide...

  6. Gel-sphere-pac fuel for thermal reactors: assessment of fabrication technology and irradiation performance

    Energy Technology Data Exchange (ETDEWEB)

    Beatty, R.L. Norman, R.E.; Notz, K.J. (comps.)

    1979-11-01

    Recent interest in proliferation-resistant fuel cycles for light-water reactors has focused attention on spiked plutonium and /sup 233/U-Th fuels, requiring remote refabrication. The gel-sphere-pac process for fabricating metal-clad fuel elements has drawn special attention because it involves fewer steps. Gel-sphere-pac fabrication technology involves two major areas: the preparation of fuel spheres of high density and loading these spheres into rods in an efficiently packed geometry. Gel sphere preparation involves three major steps: preparation of a sol or of a special solution (broth), gelation of droplets of sol or broth to give semirigid spheres of controlled size, and drying and sintering these spheres to a high density. Gelation may be accomplished by water extraction (suitable only for sols) or ammonia gelation (suitable for both sols and broths but used almost exclusively with broths). Ammonia gelation can be accomplished either externally, via ammonia gas and ammonium hydroxide, or internally via an added ammonia generator such as hexamethylenetetramine. Sphere-pac fuel rod fabrication involves controlled blending and metering of three sizes of spheres into the rod and packing by low- to medium-energy vibration to achieve about 88% smear density; these sizes have diametral ratios of about 40:10:1 and are blended in size fraction amounts of about 60% coarse, 18% medium, and 22% fine. Irradiation test results indicate that sphere-pac fuel performs at least as well as pellet fuel, and may in fact offer an advantage in significantly reducing mechanical and chemical interaction between the fuel and cladding. The normal feed for gel sphere preparation, heavy metal nitrate solution, is the usual product of fuel reprocessing, so that fabrication of gel spheres performs all the functions performed by both conversion and pellet fabrication in the case of pellet technology.

  7. Gel-sphere-pac reactor fuel fabrication and its application to a variety of fuels

    International Nuclear Information System (INIS)

    Olsen, A.R.; Judkins, R.R.

    1979-12-01

    The gel-sphere-pac fuel fabrication option was evaluated for its possible application to commercial scale fuel fabrication for 19 fuel element designs that use oxide fuel in metal clad rods. The dry gel spheres are prepared at the reprocessing plant and are then calcined, sintered, inspected, and loaded into fuel rods and packed by low-energy vibration. A fuel smear density of 83 to 88% theoretical can be obtained. All fuel fabrication process steps were defined and evaluated from fuel receiving to finished fuel element shipping. The evaluation also covers the feasibility of the process, the current status of technology, estimates of the required time and cost to develop the technology to commercial status, and the safety and licensability of commercial scale plants. The primary evaluation was for a Light-Water Reactor fuel element containing (U,Pu)O 2 fuel. The other 18 fuel element types - 3 for Light-Water Reactors, 1 for a Heavy-Water Reactor, 1 for a Gas-Cooled Fast Reactor, 7 for Liquid-Metal-Cooled Fast Breeder Reactors, and 3 pairs for Light-Water Prebreeder and Breeder Reactors - were compared with the Light-Water Reactor. The gel-sphere-pac option was found applicable to 17 of the 19 element types; the characteristics of a commercial scale plant were defined for these for making cost estimates for such plants. The evaluation clearly shows the gel-sphere-pac process to be a viable fuel fabrication option. Estimates indicate a significant potential fabrication cost advantage for the gel-sphere-pac process if a remotely operated and remotely maintained fuel fabrication plant is required

  8. Women, Drug Dependency and Consequences: A Study from a Developing Country

    Directory of Open Access Journals (Sweden)

    Mohammad Khajedaluee

    2015-01-01

    Full Text Available Introduction. Addiction in women can expose them to malnutrition, high blood pressure, cancer, and some other dangerous diseases like hepatitis, AIDS, or other sexual transmitted diseases. The aim of this study was to assess illegal sexual relations in three groups of women. Methods. This is a cross-sectional study that was done on 236 girls and young women aged 16–25 years in 2012 in three groups: vulnerable women who have substance dependency (crimes that had made women incarcerated were considered as vulnerability in this study, invulnerable women who have substance dependency (substance dependent women without a history of incarceration, and a control group (women with no history of substance dependency or being in prison. Results. 43.8% of vulnerable women who have substance dependency had extramarital sexual relations; this percentage was 55.8% in invulnerable women who have substance dependency and 1.4% in the control group. Crystal and methamphetamine abuse was higher in addicts who had extramarital sexual relations and alcohol abuse was correlated with unsafe sexual intercourse (r=;0.36, P=0.001. There was a statistically significant difference in extramarital sexual relation based on marital status (P<0.001. Conclusions. Poverty, drug dependency, divorce, and alcohol consumption make women prone to other high risk behaviors that need more attention.

  9. Cigarette smoking, nicotine dependence and anxiety disorders: a systematic review of population-based, epidemiological studies

    Directory of Open Access Journals (Sweden)

    Moylan Steven

    2012-10-01

    Full Text Available Abstract Background Multiple studies have demonstrated that rates of smoking and nicotine dependence are increased in individuals with anxiety disorders. However, significant variability exists in the epidemiological literature exploring this relationship, including study design (cross-sectional versus prospective, the population assessed (random sample versus clinical population and diagnostic instrument utilized. Methods We undertook a systematic review of population-based observational studies that utilized recognized structured clinical diagnostic criteria (Diagnostic and Statistical Manual of Mental Disorders (DSM or International Classification of Diseases (ICD for anxiety disorder diagnosis to investigate the relationship between cigarette smoking, nicotine dependence and anxiety disorders. Results In total, 47 studies met the predefined inclusion criteria, with 12 studies providing prospective information and 5 studies providing quasiprospective information. The available evidence suggests that some baseline anxiety disorders are a risk factor for initiation of smoking and nicotine dependence, although the evidence is heterogeneous and many studies did not control for the effect of comorbid substance use disorders. The identified evidence however appeared to more consistently support cigarette smoking and nicotine dependence as being a risk factor for development of some anxiety disorders (for example, panic disorder, generalized anxiety disorder, although these findings were not replicated in all studies. A number of inconsistencies in the literature were identified. Conclusions Although many studies have demonstrated increased rates of smoking and nicotine dependence in individuals with anxiety disorders, there is a limited and heterogeneous literature that has prospectively examined this relationship in population studies using validated diagnostic criteria. The most consistent evidence supports smoking and nicotine dependence as

  10. Integration in PACS of DICOM with TCP/IP, SQL, and X Windows

    Science.gov (United States)

    Reijns, Gerard L.

    1994-05-01

    The DICOM standard (Digital Imaging and Communications in Medicine) has been developed in order to obtain compatibility at the higher OSI levels. This paper describes the implementation of DICOM into our developed low cost PACS, which uses as much as possible standard software and standard protocols such as SQL, X Windows and TCP/IP. We adopted the requirement that all messages on the communication network have to be DICOM compatible. The translation between DICOM messages and SQL commands, which drive the relational data base, has been accommodated in our PACS supervisor. The translation takes only between 10 and 20 milliseconds. Images, that will be used the current day are stored in a distributed, parallel operating image base for reasons of performance. Extensive use has been made of X Windows to visualize images. A maximum of 12 images can simultaneously be displayed, of which one selected image can be manipulated (e.g., magnified, rotated, etc.), without affecting the other displayed images. The emphasis of the future work will be on performance measurements and modeling of our PACS and bringing the results of both methods in agreement with each other.

  11. The PAC-MAN model: Benchmark case for linear acoustics in computational physics

    Science.gov (United States)

    Ziegelwanger, Harald; Reiter, Paul

    2017-10-01

    Benchmark cases in the field of computational physics, on the one hand, have to contain a certain complexity to test numerical edge cases and, on the other hand, require the existence of an analytical solution, because an analytical solution allows the exact quantification of the accuracy of a numerical simulation method. This dilemma causes a need for analytical sound field formulations of complex acoustic problems. A well known example for such a benchmark case for harmonic linear acoustics is the ;Cat's Eye model;, which describes the three-dimensional sound field radiated from a sphere with a missing octant analytically. In this paper, a benchmark case for two-dimensional (2D) harmonic linear acoustic problems, viz., the ;PAC-MAN model;, is proposed. The PAC-MAN model describes the radiated and scattered sound field around an infinitely long cylinder with a cut out sector of variable angular width. While the analytical calculation of the 2D sound field allows different angular cut-out widths and arbitrarily positioned line sources, the computational cost associated with the solution of this problem is similar to a 1D problem because of a modal formulation of the sound field in the PAC-MAN model.

  12. Evaluation of video capture equipment for secondary image acquisition in the PACS.

    Science.gov (United States)

    Sukenobu, Yoshiharu; Sasagaki, Michihiro; Hirabuki, Norio; Naito, Hiroaki; Narumi, Yoshifumi; Inamura, Kiyonari

    2002-01-01

    There are many cases in which picture archiving and communication systems (PACS) are built with old-type existing modalities with no DICOM output. One of the methods for interfacing them to the PACS is to implement video capture (/ frame grabber) equipment. This equipment takes analog video signal output from medical imaging modalities, and amplitude of the video signal is A/D converted and supplied to the PACS. In this report, we measured and evaluated the accuracy at which this video capture equipment could capture the image. From the physical evaluation, we found the pixel values of an original image and its captured image were almost equal in gray level from 20%-90%. The change in the pixel values of a captured image was +/-3 on average. The change of gray level concentration was acceptable and had an average standard deviation of around 0.63. As for resolution, the degradation was observed at the highest physical level. In a subjective evaluation, the evaluation value of the CT image had a grade of 2.81 on the average (the same quality for a reference image was set to a grade of 3.0). Abnormalities in heads, chests, and abdomens were judged not to influence diagnostic accuracy. Some small differences were seen when comparing captured and reference images, but they are recognized as having no influence on the diagnoses.

  13. Adoption of PACS by the Department of Veterans Affairs: the past, the present, and future plans

    Science.gov (United States)

    Siegel, Eliot L.; Reiner, Bruce I.; Kuzmak, Peter M.

    2000-05-01

    The diffusion of PACS technology within the Department of Veterans Affairs has followed the 'S' curve transition originally described by Ryan and Gross in 1943. They described a paradigm that describes the diffusion of a new technology into the community. However the rate of adoption of filmless radiology by the VA has been much higher than that of the general healthcare system. This is likely due to the fact that the VA and Department of Defense medical systems are somewhat isolated and independent from other health care systems and are subject to a different rate of diffusion of technology. The early introduction and success of PACS in the VA undoubtedly accelerated its acceptance throughout the system. An additional impetus to the growth of PACS in the VA has been the development of an image management system that has been incorporated into the electronic medical record. The universal use of the VISTA HIS and RIS system throughout the VA and the fact that it was developed 'in-house' as well as its extensive support for DICOM functionality have also played a major role in facilitating the acceptance of Picture Archival and Communication Systems throughout the VA.

  14. Bibliographic database of PACS-related articles from the SPIE literature

    Science.gov (United States)

    Shile, Peter E.; Freiermuth, Jennifer

    1996-05-01

    Publications of the International Society of Optical Engineering (SPIE) contain much of the relevant literature on Picture Archiving and Communications Systems (PACS) and related topics. In fact, many PACS-related articles indexed by the National Library of Medicine contain references to articles published by SPIE. Unfortunately, SPIE publications themselves are not indexed by the National Library of Medicine and thus can not be identified through Medline. The lack of a convenient mechanism for searching the SPIE literature is problematic for researchers in medical imaging. With the recent introduction on SPIE's Internet server of their Abstracts Online service and their In-CiteTM title and author searching software, the SPIE literature has become more accessible. However, the searching process is still a cumbersome and time consuming process, and it is not possible to perform key word searches of manuscript abstracts. In this paper we present results of our work on developing a mechanism to more thoroughly search SPIE publications for PACS-related articles.

  15. Preparation of Extracellular Matrix Developed Using Porcine Articular Cartilage and In Vitro Feasibility Study of Porcine Articular Cartilage as an Anti-Adhesive Film

    Directory of Open Access Journals (Sweden)

    Ji Hye Baek

    2016-01-01

    Full Text Available In this study, we examined whether porcine articular cartilage (PAC is a suitable and effective anti-adhesive material. PAC, which contained no non-collagenous tissue components, was collected by mechanical manipulation and decellularization of porcine knee cartilage. The PAC film for use as an anti-adhesive barrier was easily shaped into various sizes using homemade silicone molds. The PAC film was cross-linked to study the usefulness of the anti-adhesive barrier shape. The cross-linked PAC (Cx-PAC film showed more stable physical properties over extended periods compared to uncross-linked PAC (UnCx-PAC film. To control the mechanical properties, Cx-PAC film was thermally treated at 45 °C or 65 °C followed by incubation at room temperature. The Cx-PAC films exhibited varying enthalpies, ultimate tensile strength values, and contact angles before and after thermal treatment and after incubation at room temperature. Next, to examine the anti-adhesive properties, human umbilical vein endothelial cells (HUVECs were cultured on Cx-PAC and thermal-treated Cx-PAC films. Scanning electron microscopy, fluorescence, and MTT assays showed that HUVECs were well adhered to the surface of the plate and proliferated, indicating no inhibition of the attachment and proliferation of HUVECs. In contrast, Cx-PAC and thermal-treated Cx-PAC exhibited little and/or no cell attachment and proliferation because of the inhibition effect on HUVECs. In conclusion, we successfully developed a Cx-PAC film with controllable mechanical properties that can be used as an anti-adhesive barrier.

  16. Effect of powdered activated carbon dosage on sludge properties and membrane bioreactor performance in a hybrid MBR-PAC system.

    Science.gov (United States)

    Zhang, Shi; Zuo, Xingtao; Xiong, Juan; Ma, Cong; Hu, Bo

    2017-12-22

    An improved insight into the effect of powdered activated carbon (PAC) on membrane fouling is crucial to the MBR performance. Sludge key property, soluble microbial products (SMP) and transmembrane pressure (TMP) were monitored. The membrane fouling rate in the MBRs was also analyzed based on TMP profile and resistance-in-series model. PAC reduced the membrane filtration resistance and significantly decreased the fouling rate. The sludge filterability was improved by extending the filtration time by almost twofold. PAC affected the SMP release and protein/polysaccharide (carbohydrate) was in a lower ratio. Fourier transform infrared (FTIR) analysis indicated that PAC decreased the impact of organic carbon, and reduced the proteins' and polysaccharides' absorption and deposition on the membrane surface and in the pores. The degree of reversible and irreversible fouling was related to the PAC content added into the MBRs. At the optimum dosage of 2 g/L, the results signified the PAC potential as a mitigation strategy of membrane fouling.

  17. Cultural and semantic equivalence of the activity measure post-acute care (AM-PAC) after its translation into Mandarin Chinese.

    Science.gov (United States)

    Chang, Feng-Hang; Ni, Pengsheng; Chiou, Hung-Yi; Hou, Wen-Hsuan; Jette, Alan M

    2018-03-21

    The purpose of this study was to investigate the cultural and semantic equivalence of the Activity Measure Post-Acute Care (AM-PAC) outpatient short forms after they were translated from American English to Mandarin Chinese. This study was conducted with a composite sample of a group of 483 American adults (mean age 63.1 years, 42.4% males) and 553 Taiwanese adults (mean age 60.6 years, 47.2% males) who were undergoing home care or outpatient rehabilitation services. A confirmatory factor analysis tested the cultural equivalence of the AM-PAC dimensions between the US and Taiwanese samples. Semantic equivalence was tested through an item response theory-based differential item functioning (DFI) analysis. Results of the confirmatory factor analysis demonstrated good model-data fit of the AM-PAC in both the US and Taiwanese samples. Significant DFI was found for six Basic Mobility items, two Daily Activity items, and four Applied Cognition items. A DFI-adjusted conversion table was generated to transform the raw scores of the measure for comparisons between the two countries. This study provides evidence to support the conceptual equivalence of the AM-PAC when used in rehabilitation patients between American and Taiwanese cultural contexts. Some DFI items between the two groups were found, suggesting that some differences in semantic understanding of these items between cultures require cross-cultural adjustments. Implications for Rehabilitation Cultural equivalence needs to be tested before applying a clinical measure to another context. The findings of this study supported the three activity domains that the Activity Measure Post-Acute Care measures: Basic Mobility, Daily Activity, and Applied Cognition, which are all important rehabilitation outcomes that need to be assessed and monitored across rehabilitation settings. Differential item functioning was observed between the English and Chinese versions of the Activity Measure Post-Acute Care, indicating that

  18. Assessment of abstract reasoning abilities in alcohol-dependent subjects: an fMRI study

    International Nuclear Information System (INIS)

    Bagga, Deepika; Singh, Namita; Singh, Sadhana; Modi, Shilpi; Kumar, Pawan; Bhattacharya, D.; Garg, Mohan L.; Khushu, Subash

    2014-01-01

    Chronic alcohol abuse has been traditionally associated with impaired cognitive abilities. The deficits are most evident in higher order cognitive functions, such as abstract reasoning, problem solving and visuospatial processing. The present study sought to increase current understanding of the neuropsychological basis of poor abstract reasoning abilities in alcohol-dependent subjects using functional magnetic resonance imaging (fMRI). An abstract reasoning task-based fMRI study was carried out on alcohol-dependent subjects (n = 18) and healthy controls (n = 18) to examine neural activation pattern. The study was carried out using a 3-T whole-body magnetic resonance scanner. Preprocessing and post processing was performed using SPM 8 software. Behavioral data indicated that alcohol-dependent subjects took more time than controls for performing the task but there was no significant difference in their response accuracy. Analysis of the fMRI data indicated that for solving abstract reasoning-based problems, alcohol-dependent subjects showed enhanced right frontoparietal neural activation involving inferior frontal gyrus, post central gyrus, superior parietal lobule, and occipito-temporal gyrus. The extensive activation observed in alcohol dependents as compared to controls suggests that alcohol dependents recruit additional brain areas to meet the behavioral demands for equivalent task performance. The results are consistent with previous fMRI studies suggesting decreased neural efficiency of relevant brain networks or compensatory mechanisms for the execution of task for showing an equivalent performance. (orig.)

  19. Assessment of abstract reasoning abilities in alcohol-dependent subjects: an fMRI study

    Energy Technology Data Exchange (ETDEWEB)

    Bagga, Deepika; Singh, Namita; Singh, Sadhana; Modi, Shilpi; Kumar, Pawan [Institute of Nuclear Medicine and Allied Sciences (INMAS), NMR Research Centre, Delhi (India); Bhattacharya, D. [Base Hospital, Department of Psychiatry, Delhi Cantt (India); Garg, Mohan L. [Panjab University, Department of Biophysics, Chandigarh (India); Khushu, Subash [Institute of Nuclear Medicine and Allied Sciences (INMAS), NMR Research Centre, Delhi (India); INMAS, DRDO, NMR Research Centre, Delhi (India)

    2014-01-15

    Chronic alcohol abuse has been traditionally associated with impaired cognitive abilities. The deficits are most evident in higher order cognitive functions, such as abstract reasoning, problem solving and visuospatial processing. The present study sought to increase current understanding of the neuropsychological basis of poor abstract reasoning abilities in alcohol-dependent subjects using functional magnetic resonance imaging (fMRI). An abstract reasoning task-based fMRI study was carried out on alcohol-dependent subjects (n = 18) and healthy controls (n = 18) to examine neural activation pattern. The study was carried out using a 3-T whole-body magnetic resonance scanner. Preprocessing and post processing was performed using SPM 8 software. Behavioral data indicated that alcohol-dependent subjects took more time than controls for performing the task but there was no significant difference in their response accuracy. Analysis of the fMRI data indicated that for solving abstract reasoning-based problems, alcohol-dependent subjects showed enhanced right frontoparietal neural activation involving inferior frontal gyrus, post central gyrus, superior parietal lobule, and occipito-temporal gyrus. The extensive activation observed in alcohol dependents as compared to controls suggests that alcohol dependents recruit additional brain areas to meet the behavioral demands for equivalent task performance. The results are consistent with previous fMRI studies suggesting decreased neural efficiency of relevant brain networks or compensatory mechanisms for the execution of task for showing an equivalent performance. (orig.)

  20. Dependency in elderly people newly diagnosed with cancer - A mixed-method study

    DEFF Research Database (Denmark)

    Esbensen, Bente Appel; Thomé, Bibbi; Thomsen, Thordis

    2012-01-01

    PURPOSE: This study, based on data from an empirical investigation, combines quantitative and qualitative approaches in a mixed-method design to explore dependency in elderly people newly diagnosed with cancer. METHODS AND SAMPLE: 101 elderly people newly diagnosed with cancer were included...... in the quantitative part, with 16 in the qualitative part. A questionnaire concerning quality of life and dependency issues was developed. For the qualitative part, open-ended interviews were conducted to get closer to the experience of dependency. RESULTS: Combining the two methods was seen as complementary...

  1. Motivation and exercise dependence: a study based on self-determination theory.

    Science.gov (United States)

    González-Cutre, David; Sicilia, Alvaro

    2012-06-01

    The objective of this study was to use self-determination theory to analyze the relationships of several motivational variables with exercise dependence. The study involved 531 exercisers, ranging in age from 16 to 60 years old, who responded to differentquestionnaires assessing perception of motivational climate, satisfaction of basic psychological needs, motivation types, and exercise dependence. The results of multiple mediation analysis revealed that ego-involving climate and perceived competence positively predicted exercise dependence in a directed and mediated manner through introjected and external regulation. Gender and age did not moderate the analyzed relationships. These results allow us to better understand the motivational process explaining exercise dependence, demonstrating the negative influence of the ego-involving climate in the context of exercise.

  2. Study of energetic dependence of LiF TLDs for photons

    Energy Technology Data Exchange (ETDEWEB)

    Cavalieri, Tassio A.; Antunes, Paula C.G.; Paiva, Fabio; Branco, Isabela S.; Sena, Michelle K.S.; Siqueira, Paulo T.D.; Yoriyaz, Helio, E-mail: tcavalieri@usp.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2015-07-01

    The LiF TLDs are widely used for photon dosimetry. However, in the most case the energetic dependence of these TLDs are not taken into account. This work is a preliminary study of energetic photon dependence in LiF TLD (TLD 700, enriched with {sup 7}Li). For this study it was utilized a methodology already used in others works that seek understand the dependence energetic of TLD. It was utilized three different X-ray spectrum and a {sup 137}Cs source; Beyond the calculus utilized in previous works, it was built the calibration curve for each spectrum to see the difference in dosimetry that the energetic dependence could cause. (author)

  3. Vascular risk factor burden, atherosclerosis, and functional dependence in old age: a population-based study.

    Science.gov (United States)

    Welmer, Anna-Karin; Liang, Yajun; Angleman, Sara; Santoni, Giola; Yan, Zhongrui; Cai, Chuanzhu; Qiu, Chengxuan

    2014-08-01

    Vascular risk factors such as hypertension and obesity have been associated with physical limitations among older adults. The purpose of this study is to examine whether individual and aggregated vascular risk factors (VRFs) are associated with functional dependence and to what extent carotid atherosclerosis (CAS) or peripheral artery disease (PAD) may mediate the possible associations of aggregated VRFs with functional dependence. This cross-sectional study included 1,451 community-living participants aged ≥60 years in the Confucius Hometown Aging Project of China. Data on demographic features, hypertension, high total cholesterol, obesity, smoking, physical inactivity, diabetes, CAS, PAD, and cardiovascular diseases (CVDs) were collected through an interview, a clinical examination, and laboratory tests. Functional dependence was defined as being dependent in at least one activity in the personal or instrumental activities of daily living. Data were analyzed using multiple logistic models controlling for potential confounders. We used the mediation model to explore the potential mediating effect of CAS and PAD on the associations of aggregated VRFs with functional dependence. Of the 1,451 participants, 222 (15.3%) had functional dependence. The likelihood of functional dependence increased linearly with increasing number of VRFs (hypertension, high total cholesterol, abdominal obesity, and physical inactivity) (p for trend <0.002). Mediation analysis showed that controlling for demographics and CVDs up to 11% of the total association of functional dependence with clustering VRFs was mediated by CAS and PAD. Aggregation of multiple VRFs is associated with an increased likelihood of functional dependence among Chinese older adults; the association is partially mediated by carotid and peripheral artery atherosclerosis independently of CVDs.

  4. Oppositional defiant disorder (ODD), the forerunner of alcohol dependence: a controlled study.

    Science.gov (United States)

    Ghosh, Abhishek; Malhotra, Savita; Basu, Debasish

    2014-10-01

    There are common genetic, neurobiological and psycho-social substrates for oppositional defiant disorder (ODD) and substance dependence. ODD can be regarded as the mildest and earliest form of disruptive behavioral disorder and also represents the threshold of vulnerability for substance dependence. But it is a less researched area. The aim of this research was to study any possible association between childhood ODD and adult alcohol dependence. Data are presented from a non probability sample of 100 adult alcohol dependent subjects and equal number of biologically unrelated control subjects. Assessment was conducted by the instrument Semi-Structured Assessment for the Genetics of Alcoholism for both the assessment of ODD and alcohol dependence. The results of this study demonstrated significant association between childhood ODD and adult alcohol dependence. The association remained significant even after the exclusion of the possible confounding effects of the presence of conduct disorder and attention deficit hyperactivity disorder. Our study should encourage further research in this area and is expected to open up an opportunity for preventive research. Copyright © 2014 Elsevier B.V. All rights reserved.

  5. A Study of the Temperature Dependence of Bienzyme Systems and Enzymatic Chains

    Directory of Open Access Journals (Sweden)

    N. V. Kotov

    2007-01-01

    Full Text Available It is known that most enzyme-facilitated reactions are highly temperature dependent processes. In general, the temperature coefficient, Q10, of a simple reaction reaches 2.0–3.0. Nevertheless, some enzyme-controlled processes have much lower Q10 (about 1.0, which implies that the process is almost temperature independent, even if individual reactions involved in the process are themselves highly temperature dependent. In this work, we investigate a possible mechanism for this apparent temperature compensation: simple mathematical models are used to study how varying types of enzyme reactions are affected by temperature. We show that some bienzyme-controlled processes may be almost temperature independent if the modules involved in the reaction have similar temperature dependencies, even if individually, these modules are strongly temperature dependent. Further, we show that in non-reversible enzyme chains the stationary concentrations of metabolites are dependent only on the relationship between the temperature dependencies of the first and last modules, whilst in reversible reactions, there is a dependence on every module. Our findings suggest a mechanism by which the metabolic processes taking place within living organisms may be regulated, despite strong variation in temperature.

  6. Stigmatization of people with drug dependence in China: a community-based study in Hunan province.

    Science.gov (United States)

    Luo, Tao; Wang, Jing; Li, Yanhua; Wang, Xuyi; Tan, Linxiang; Deng, Qijian; Thakoor, Jaya Prishni Devi; Hao, Wei

    2014-01-01

    Drug abuse remains a serious problem in China, and has become a major threat to public health and social security. Since the issuance and enforcement of the new Anti-Drug law in 2008, the community has become the primary site for drug rehabilitation. However, the attitudes of members in community toward the people with drug use disorders are unclear. A random sample of household respondents was studied in two communities in Hunan province in China. A total of 848 individuals participated (response rate 83.7%). Respondents initially were asked a set of questions about their knowledge about dug dependence, and then were randomly assigned to 1 of 4 vignette conditions. Three vignettes described different type of drug dependence meeting diagnostic criteria, and the fourth depicted a "normal person." Poor knowledge of drug dependence was common. Negative attitudes towards drug dependent people were widespread. Most respondents believed that drug dependence was caused by the person's own weak will (82.0%) and own hedonistic lifestyle (81.3%), and should be punished as illegal behavior (80.4%). The vast majority labeled the person with drug dependence as an addict, rated them as having undesirable characteristics, and expressed a strong desire for social distance. There were few socio-demographic predictors of both poor knowledge and negative attitudes. A community-based rehabilitation program in China should take into account the widespread stigmatization of people with drug dependence. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  7. A Study of Daily Living Dependency Status among Elderly in an Urban Slum area of Dehradun

    Directory of Open Access Journals (Sweden)

    Puneet Ohri

    2014-12-01

    Full Text Available Background: Population aging is observed world-wide. As per Census 2011, elderly constitutes 7.4% population of India. It is expected to increase to 20% in 2050. This segment of population faces multiple medical and psychological problems. To address and solve these problems great effort from the country and the community is required. Objective: To assess the daily living dependency status among elderly. Method:  A cross sectional study was conducted in Dehradun, among 215 elderly people, using a pre-structured questionnaire. Their activities of daily living (ADL and Instrumental activities of daily living (IADL were recorded by observation and interviewing them with their families. Results: Out of total, 93% individuals were independent in their ADLs, with more dependence in the very old elderly. Maximum inability was found in Bathing and dressing. 70.7% elderly were dependent on one or more IADLs, female elderly being more dependent than male (p<0.05. However there was no significant difference of dependence in the male and female elderly in performing ADLs. Education and socio-economic status had a positive effect on independence in IADLs. Among all IADLs male elderly showed a maximum dependency for cooking and laundry while females showed a greater dependency in using telephone, managing money and travelling.

  8. A Preliminary Study of Sexual Dysfunction in Male Opioid-Dependants under Methadone Maintenance Treatment

    Directory of Open Access Journals (Sweden)

    Masoudeh Babakhanian

    2011-08-01

    Full Text Available Introduction: Sexual dysfunction is one of the prevalent problems of opiate-dependent patients. The current preliminarily study examines sexual dysfunction in a group of opiate-dependent patients before and after 6 months of MMT. Methods: The current study is a cross-sectional study. The numbers of 30 opiate-dependent patients were selected of Cheraghiyan clinic in Damghan, Iran. Demographics questionnaire and the International Index of Erectile Function were administered before and after treatment. Results: Erectile function showed an increase and intercourse satisfactions completely improved. Sexual desire and overall satisfaction increased, showing slight improvement while orgasmic function increased showing no improvement. Discussion: The findings revealed the prevalence of sexual dysfunction and improvement of some component in patients after treatment. Future studies are needed to explore the roles of other factors.

  9. Sleep disturbance and its associations with severity of dependence, depression and quality of life among heroin-dependent patients: a cross-sectional descriptive study.

    Science.gov (United States)

    Chen, Vincent Chin-Hung; Ting, Hua; Wu, Meng-Huan; Lin, Tsang-Yaw; Gossop, Michael

    2017-03-20

    Sleep disturbance is common and may adversely affect treatment outcome, mental health, and quality of life in heroin-dependent patients. Previous studies have focused upon patients receiving treatment. We conducted a cross-sectional descriptive study to explore the 1-month prevalence of sleep disturbance and its associations with socio-demographic, substance-related characteristics, severity of dependence, severity of depression, and quality of life among heroin-dependent patients before entering treatment program. The sample (n = 514) comprised individuals with heroin dependence attending the methadone maintenance treatment program and the therapeutic community at a psychiatric center in Nantou, Taiwan between 2008 and 2014. Sleep quality was measured using Pittsburgh Sleep Quality Index (PSQI) with a global score greater than 5 indicating sleep disturbance. Centre for Epidemiologic Studies Depression Scale, Severity of Dependence Scale, and World Health Organization Quality of Life-BREF were also approached. T-test, chi-square tests, and multivariate logistic regression were performed to measure associations between variables and sleep disturbance. The 1-month prevalence of sleep disturbance (PSQI > 5) was 76.3% among 514 subjects with heroin dependence. Heroin users with sleep disturbance had significantly more life events in the previous year, higher rate of unemployment, greater cigarette consumption, more substance related criminal convictions, longer length of heroin use, higher rate of injectors, greater severity of dependence, greater severity of depression, and lower quality of life compared to those without sleep disturbance. Severity of dependence, severity of depression, and physical health domain of quality of life remained significantly associated with sleep disturbance after adjusting for other variables. Heroin-dependent patients had a high 1-month prevalence of sleep disturbance, and this was associated with greater severity of dependence

  10. The Study of Mental Health and its Relationship with Quality of Life in Substance Dependents

    Directory of Open Access Journals (Sweden)

    Marzeh Efati

    2012-08-01

    Full Text Available Introduction: Substance dependents encounter with many problems which cause confusion in their quality of life. Method: This survey is a descriptive-analytical study. In this survey 150 persons of substance dependents who refer to addiction recovery centers at Rasht were selected by available sampling method. Information was collected via mental health questionnaire (GHQ-28 and quality of life questionnaire of World Health Organization. Results: Findings showed a significant relation between quality of life and mental health of substance dependents. Also results of simultaneous regression showed that many components of quality of life were correlated to mental health components. Mental health domain of quality of life showed significant correlation with 3 domains namely: anxiety, social dysfunction and depression. Also physical health domain of quality of life showed significant correlation with somatization domain of mental health. Conclusion: It could be possible to increase mental health of substance dependents by improving of quality of life, in accordance to survey findings.

  11. Effect of opium dependency on secondary intention wound healing in a rat model: an experimental study.

    Science.gov (United States)

    Vahedian, Jalal; Mirshekari, Tooraj-Reza; Nabavizadeh, Fatemeh

    2013-06-01

    Opium dependency is a social and health problem in some middle eastern countries like Iran. Many of these people may require surgery. This study investigates the effects of opium dependency on histological parameters of secondary intention wound healing in rat. A full-thickness wound (2 × 2 cm in diameters) was created on the dorsum of two groups of rats, a normal control group and a second group of rat depended to opium (Badawy's method). Several times during 14 days postwounding, the wound was excised with peripheral margins of normal skin and was evaluated for cellular population, reepithelialisation and revascularisation. Results are presented as the mean ± standard error. Data were compared by an unpaired t-test or analysis of variance. Histological examination of the wound tissue showed evidence of increased population of fibroblasts, decreased recruitment of neutrophile and plateau of macrophage cells in opium depended animals comparing with control group. In the depended animals, reepithelialisation was seen to be enhanced significantly, while prohibiting progression of revascularisation. This study shows that opium dependency enhances reepitheliazation as well as tissue recruitment of fibroblasts; thereby probable enhancement of secondary intention wound healing. © 2012 The Authors. International Wound Journal © 2012 John Wiley & Sons Ltd and Medicalhelplines.com Inc.

  12. Task Dependency Effects of Collaboration in Learners' Corpus Consultation: An Exploratory Case Study

    Science.gov (United States)

    Cho, Hyeyoung

    2016-01-01

    Collaborative learning has attracted attention as pedagogic mediation to assist learners' corpus consultation, but some studies have pointed to negative aspects of collaboration. Based on the two sides of collaboration in language learning, this study presents a qualitative investigation of different effects of collaboration depending on task…

  13. Motivation and Exercise Dependence: A Study Based on Self-Determination Theory

    Science.gov (United States)

    Gonzalez-Cutre, David; Sicilia, Alvaro

    2012-01-01

    The objective of this study was to use self-determination theory to analyze the relationships of several motivational variables with exercise dependence. The study involved 531 exercisers, ranging in age from 16 to 60 years old, who responded to different questionnaires assessing perception of motivational climate, satisfaction of basic…

  14. Epidemiology of behavioral dependence: literature review and results of original studies.

    Science.gov (United States)

    Lejoyeux, M; Mc Loughlin, M; Adès, J

    2000-03-01

    The extension of the definition of dependence leads to the consideration of some impulsive disorders as a form of dependence disorder. This pathological condition is characterized by the repetitive occurrence of impulsive and uncontrolled behaviors. Other clinical characteristics are failure to resist an impulse, drive or temptation to perform some act harmful to oneself and/or others, an increasing sense of tension or excitement before acting out, and a sense of pleasure, gratification or release at the time of the behavior or shortly thereafter. Behavioral dependences most often described are pathological gambling, kleptomania, trichotillomania and compulsive buying. Studies using a specific assessment scale, the South Oaks Gambling Screen, distinguished problem gambling from pathological gambling. Social gamblers spend 5% of their money and pathological gamblers 14 to 45%. Prevalence of 'problem gambling' is 4% and pathological gambling 2%. Several studies have suggested that the incidence of pathological gambling is eight to ten times greater in alcohol-dependent patients than in the general population. No systematic study has assessed the prevalence of kleptomania. Data come from case reports. Among subjects arrested after a theft, prevalence of kleptomania varied between 0 and 24%. Trichotillomania prevalence rate is 0.6% among students. Studies using less restrictive diagnostic criteria found a prevalence rate of 3.4% in women and 1.5% in men. The disorder is often unrecognized; 40% of the cases are not diagnosed and 58% of the patients have never been treated. Prevalence studies of compulsive buying found a rate between 1 and 6% in the general population. Compulsive buying is significantly more frequent among women (90% of the cases). Study of family history of compulsive buyers showed a high frequency of alcohol-dependence disorder (20%) and depression (18%). In all cases of behavioral dependence disorders, a high level of impulsivity and sensation

  15. Report of the CEBAF PAC4 Subcomittee on STAR

    International Nuclear Information System (INIS)

    Barnes, P.D.

    1990-01-01

    This report discusses the following topics: the symmetric toroidal array (STAR) spectrometer facility; investigation of the N → Δ transition; Hyperon production in the (e, e'k) reactions; investigation of few-body systems with the (e, e'p) reaction; nuclear structure studies with the (e,e'pp) reaction; Measurement of G Em in a recoil polarimetry measurement; parity violation measurements; and STAR design and performance

  16. Design and evaluation of hydraulic baffled-channel PAC contactor for taste and odor removal from drinking water supplies.

    Science.gov (United States)

    Kim, Young-Il; Bae, Byung-Uk

    2007-05-01

    Based on the concept of hydraulic flocculator, a baffled-channel powdered activated carbon (PAC) contactor, placed before the rapid-mixing basin, was designed and evaluated for removal of taste and odor (T&O) in drinking water. PAC adsorption kinetic tests for raw water samples were conducted for selection of design parameters related to contact time and degree of mixing. Within the tested range of velocity gradient (G) from 18 to 83s(-1), mixing had a relatively minor effect on the adsorption kinetics of the PAC. The hydrodynamic characteristics of the pilot-scale horizontally and vertically baffled-channel PAC contactor were investigated by tracer tests. It was found that the plug flow fractions of vertically baffled-channel PAC contactor (vBPC) were higher than those of the horizontally baffled-channel PAC contactor (hBPC) for the same bend width or bend height. However, the hBPC seems to be more appropriate than the vBPC in terms of construction and maintenance. The geosmin and MIB removal rate increased with the number of baffles, PAC dose and contact time increased regardless of bend width in the pilot-scale hBPC. The pair of full-scale hBPCs at Pohang water treatment plant, having a design capacity of 6.5x10(4)m(3)/d with 20min of hydraulic retention time with a safety factor of 2, was designed based on lab- and pilot-scale experimental results. Under a velocity gradient of 20s(-1), the number of baffles to be installed was calculated to be 20 with a space of about 2m between each baffle, resulting in a hydraulic head loss through the contactor of about 0.056m. The successful application of hBPC for T&O removal from drinking water supplies should provide momentum for developing more effective treatment methods.

  17. Absence of phase-dependent noise in time-domain reflectivity studies of impulsively excited phonons

    KAUST Repository

    Hussain, A.

    2010-06-17

    There have been several reports of phase-dependent noise in time-domain reflectivity studies of optical phonons excited by femtosecond laser pulses in semiconductors, semimetals, and superconductors. It was suggested that such behavior is associated with the creation of squeezed phonon states although there is no theoretical model that directly supports such a proposal. We have experimentally re-examined the studies of phonons in bismuth and gallium arsenide, and find no evidence of any phase-dependent noise signature associated with the phonons. We place an upper limit on any such noise at least 40–50 dB lower than previously reported.

  18. Study of energy dependence of a extrapolation chamber in low energy X-rays beams

    International Nuclear Information System (INIS)

    Bastos, Fernanda M.; Silva, Teogenes A. da

    2014-01-01

    This work was with the main objective to study the energy dependence of extrapolation chamber in low energy X-rays to determine the value of the uncertainty associated with the variation of the incident radiation energy in the measures in which it is used. For studying the dependence of energy, were conducted comparative ionization current measurements between the extrapolation chamber and two ionization chambers: a chamber mammography, RC6M model, Radcal with energy dependence less than 5% and a 2575 model radioprotection chamber NE Technology; both chambers have very thin windows, allowing its application in low power beams. Measurements were made at four different depths of 1.0 to 4.0 mm extrapolation chamber, 1.0 mm interval, for each reference radiation. The study showed that there is a variable energy dependence on the volume of the extrapolation chamber. In other analysis, it is concluded that the energy dependence of extrapolation chamber becomes smaller when using the slope of the ionization current versus depth for the different radiation reference; this shows that the extrapolation technique, used for the absorbed dose calculation, reduces the uncertainty associated with the influence of the response variation with energy radiation

  19. A Qualitative Study into Dependent Relationships and Voluntary Informed Consent for Research in Pediatric Oncology.

    Science.gov (United States)

    Dekking, Sara A S; van der Graaf, Rieke; Schouten-van Meeteren, Antoinette Y N; Kars, Marijke C; van Delden, Johannes J M

    2016-04-01

    In pediatric oncology, many oncologists invite their own patients to participate in research. Inclusion within a dependent relationship is considered to potentially compromise voluntariness of consent. Currently, it is unknown to what extent those involved in pediatric oncology experience the dependent relationship as a threat to voluntary informed consent, and what they see as safeguards to protect voluntary informed consent within a dependent relationship. We performed a qualitative study among key actors in pediatric oncology to explore their experiences with the dependent relationship and voluntary informed consent. We conducted three focus groups and 25 semi-structured, in-depth interviews with pediatric oncologists, research coordinators, Research Ethics Committee members, parents of children with cancer, and adolescents with cancer. Professionals regarded the dependent relationship both as a potential threat to and as a positive influence on voluntary decision making. Parents and adolescents did not feel as though dependency upon the oncologist influenced their decisions. They valued the involvement of their own physician in the informed consent process. The professionals suggested three strategies to protect voluntariness: emphasizing voluntariness; empowering families; involvement of an independent person. Although the dependent relationship between pediatric oncologists, patients and parents may be problematic for voluntary informed consent, this is not necessarily the case. Moreover, the involvement of treating physicians may even have a positive impact on the informed consent process. Although we studied pediatric oncology, our results may also apply to many other fields of pediatric medicine where research and care are combined, for example, pediatric rheumatology, neurology and nephrology. Clinical trials in these fields are inevitably often designed, initiated and conducted by medical specialists closely involved in patient care.

  20. PACS for surgery and interventional radiology: Features of a Therapy Imaging and Model Management System (TIMMS)

    International Nuclear Information System (INIS)

    Lemke, Heinz U.; Berliner, Leonard

    2011-01-01

    Appropriate use of information and communication technology (ICT) and mechatronic (MT) systems is viewed by many experts as a means to improve workflow and quality of care in the operating room (OR). This will require a suitable information technology (IT) infrastructure, as well as communication and interface standards, such as specialized extensions of DICOM, to allow data interchange between surgical system components in the OR. A design of such an infrastructure, sometimes referred to as surgical PACS, but better defined as a Therapy Imaging and Model Management System (TIMMS), will be introduced in this article. A TIMMS should support the essential functions that enable and advance image guided therapy, and in the future, a more comprehensive form of patient-model guided therapy. Within this concept, the 'image-centric world view' of the classical PACS technology is complemented by an IT 'model-centric world view'. Such a view is founded in the special patient modelling needs of an increasing number of modern surgical interventions as compared to the imaging intensive working mode of diagnostic radiology, for which PACS was originally conceptualised and developed. The modelling aspects refer to both patient information and workflow modelling. Standards for creating and integrating information about patients, equipment, and procedures are vitally needed when planning for an efficient OR. The DICOM Working Group 24 (WG-24) has been established to develop DICOM objects and services related to image and model guided surgery. To determine these standards, it is important to define step-by-step surgical workflow practices and create interventional workflow models per procedures or per variable cases. As the boundaries between radiation therapy, surgery and interventional radiology are becoming less well-defined, precise patient models will become the greatest common denominator for all therapeutic disciplines. In addition to imaging, the focus of WG-24 is to serve

  1. Study on the energy dependence of gamma radiation detectors for 137Cs and 60Co

    International Nuclear Information System (INIS)

    Nonato, Fernanda B.C.; Diniz, Raphael E.; Carvalho, Valdir S.; Vivolo, Vitor; Caldas, Linda V.E.

    2009-01-01

    38 Geiger-Mueller radiation detectors and 9 ionization chambers were calibrated, viewing to study the energy dependence of the monitor response for gamma radiation fields ( 137 Cs and 60 Co). The results were considered satisfactory only for ionization chambers and for some Geiger-Mueller detectors

  2. Light-dependent pigment migration in blowfly photoreceptors studied by in vivo CLSM

    NARCIS (Netherlands)

    Stavenga, DG; Leertouwer, HL; Smits, RP

    The light-dependent migration of pigment granules in the soma of fly photoreceptors has been studied in vivo with a fast confocal laser scanning microscope. Images as well as photometric measurements were obtained in the reflection and fluorescence modes. Measurements at the single cell level were

  3. A double-blind, placebo-controlled study of sertraline with naltrexone for alcohol dependence.

    LENUS (Irish Health Repository)

    Farren, Conor K

    2009-01-01

    Significant preclinical evidence exists for a synergistic interaction between the opioid and the serotonin systems in determining alcohol consumption. Naltrexone, an opiate receptor antagonist, is approved for the treatment of alcohol dependence. This double-blind placebo-controlled study examined whether the efficacy of naltrexone would be augmented by concurrent treatment with sertraline, a selective serotonin receptor uptake inhibitor (SSRI).

  4. STEM - software test and evaluation methods. A study of failure dependency in diverse software

    International Nuclear Information System (INIS)

    Bishop, P.G.; Pullen, F.D.

    1989-02-01

    STEM is a collaborative software reliability project undertaken in partnership with Halden Reactor Project, UKAEA, and the Finnish Technical Research Centre. The objective of STEM is to evaluate a number of fault detection and fault estimation methods which can be applied to high integrity software. This Report presents a study of the observed failure dependencies between faults in diversely produced software. (author)

  5. BONE-DENSITY IN NON-INSULIN-DEPENDENT DIABETES-MELLITUS - THE ROTTERDAM STUDY

    NARCIS (Netherlands)

    VANDAELE, PLA; STOLK, RP; BURGER, H; ALGRA, D; GROBBEE, DE; HOFMAN, A; BIRKENHAGER, JC; POLS, HAP

    1995-01-01

    Objective: To investigate the relation between noninsulin-dependent diabetes mellitus and bone mineral density at the lumbar spine and hip. Design: Population-based study with a cross-sectional survey, Setting: A district of Rotterdam, the Netherlands. Participants: 5931 residents (2481 men, 3450

  6. Las dudas sobre el ascenso pacífico de China

    OpenAIRE

    Rubio Plo, Antonio R.

    2015-01-01

    China parece estar aprovechando su poder económico en el escenario internacional para aumentar su capacidad política y ejercer un papel relevante en las relaciones internacionales. Pero existen razones suficientes para pensar que el ascenso chino no será pacífico. Como ha explicado en sus obras John J. Mearsheimer, las relaciones entre China y los Estados Unidos pueden resultar tan o más comprometidas como las que marcaron el enfrentamiento con la URSS durante la guerra fría.

  7. Perturbed Angular Correlation (PAC)/NMR spectroscopic properties and dynamics of compounds containing metal ions

    DEFF Research Database (Denmark)

    Arcisauskaité, Vaida

    199mHg PAC and 199Hg NMR spectroscopic properties, nuclear quadrupole coupling constants, Q, asymmetry parameters, , and chemical shifts, , respectively, are the fingerprint of the local molecular and electronic structure, at the probed Hg nuclei. For this reason, these spectroscopic techniques...... computationally demanding Coupled Cluster results. We also determined to what degree the computationally cheaper approximate relativistic methods ZORA(-4) and SR-ZORA-4 at the DFT level can reproduce fully-relativistic results. As a result, we proposed reliable computational methods applicable to Hg binding sites...

  8. Los cristeros del volcán y los pacíficos de La Esperanza

    OpenAIRE

    JULIA PRECIADO ZAMORA

    2008-01-01

    Este artículo analiza el caso de dos comunidades en la zona sur del estado de Jalisco, Tonila y La Esperanza, durante el levantamiento cristero. Pese a que dichas comunidades estaban separadas por escasos tres kilómetros de distancia, optaron por posturas políticas rivales:Tonila se pronunció por el bando cristero, mientras que La Esperanza se mantuvo pacífica. Julia Preciado propone que las figuras del obispo de Colima, José Amador Velasco y del hacendado alemán Enrique Schöndube, influyero...

  9. Oportunidades y amenazas para Colombia de pertenecer a la Alianza del Pacífico

    OpenAIRE

    Piedrahita Valencia, Paula Andrea

    2015-01-01

    Por medio de este proyecto se analizaron las asimetrías presentes en las economías de los cuatro países miembros de la Alianza del Pacífico y cómo Colombia puede enfrentar estos y retos y convertirlos en oportunidades de acuerdo a la experiencia en diferentes áreas de sus países aliados. De acuerdo a las bases de datos de los países firmantes se encontró que la balanza comercial entre Colombia y México presenta un déficit y está en constante crecimiento, pudiendo ser contrarrestada con fut...

  10. Full-Length Mitochondrial-DNA Sequencing on the PacBio RSII.

    Science.gov (United States)

    Vossen, Rolf H A M; Buermans, Henk P J

    2017-01-01

    Conventional mitochondrial-DNA (MT DNA) sequencing approaches use Sanger sequencing of 20-40 partially overlapping PCR fragments per individual, which is a time- and resource-consuming process. We have developed a high-throughput, accurate, fast, and cost-effective human MT DNA sequencing approach. In this setup we first generate long-range PCR products for two partially overlapping 7.7 and 9.2 kb MT DNA-specific amplicons, add sample-specific barcodes, and sequence these on the PacBio RSII system to obtain full-length MT DNA sequences for genotyping/haplotyping purposes.

  11. Invertebrados marinos de importancia comercial en la costa Pacífica de Panamá.

    OpenAIRE

    Posada, J. M.; Piedra, A.; Ross, E.; Díaz, J.M.; Sánchez, G. Nikolas; Guerra, Z.; De Leon, M.

    2014-01-01

    En la costa del Pacífico de Panamá se concentra el 95% de la actividad pesquera del país y el 80% de su población. La pesca es de suma importancia en nuestra economía, es el segundo producto de exportación después del banano y representa una fuente de empleo considerable para las poblaciones costeras. Los invertebrados marinos (langosta, camarón y moluscos) representaron, entre el 2003 y el 2012, un promedio del 11% del total de las exportaciones de los productos acuático...

  12. Registros de Jabiru mycteria en la costa pacífica de Honduras

    OpenAIRE

    Marineros, Leonel

    1996-01-01

    Este es el primer reporte de jaribu mycteria en la costa del Pacífico de Honduras. Estas aves se alimentan y descansan en dos estanques invernales, las lagunas El Jicarito y El Faro. Ambos sitios son afectados por la cría de ganado, la pesca artesanal y la cría de camarones. This is the first report of Jabiru mycteria in the Pacific coast of Honduras. This bird feeds and rests in two winter ponds El Jicarito and El Faro lagoons. Both sites are affected by cattle ranching, artesanal fishing...

  13. PACS image archive server implementation in the developing countries such as China

    Science.gov (United States)

    Zhang, Dong; Shu, Yunhong; Zhuang, Tian-ge

    2000-05-01

    While Picture Archiving and Communicating System project is underway through out the western countries, China is making a revolutionary advance in digital medical record. Hospitals in China have made their first steps toward implementation of PACS. Due to the ever-increasing amount of medical image data, a completed archive server is of great need as the base of filmless radiology, a cost effective, high performance digital archive system will remain as the most essential and challenging part of PACS. However there is an inevitable and inherent dilemma in those hospitals in the developing countries like China -- limited amount of development funds. So we are urged to design a low cost but efficient image archive system to cater to the expectation of the hospital. This paper describes a high capacity PACS image archive system model that is developed with rather low cost. To build a reliable and flexible image archive system involves a number of factors such as system capacity requirement, storage and retrieval performance and cost saving etc. We have undertaken the hierarchy image storage mechanism. Judicious image dispatch is employed to meet the goal of timely image retrieval. The whole design can be divided into two parts, one is Scheduled Image Flow Service (SIFS) whose purpose is to periodically backup, archive and pre-fetch image, the other one is Online Image Retrieval Service (OIRS) to provide quick access to the online and nearline images through the network interface. Automatic image transfer is realized between different storage tiers with high level of control. All the procedure is highly automatic except the manually depositing and undepositing off-line optical disks. System evaluations on random retrieval time are presented to show the effect of image location. The concept of image tiered storage will largely reduce the cost of storage. Real-time response to the retrieval demand can send wanted images to a radiologist in a reasonable time. We have done

  14. Laboratory effluent Treatment by Using Coagulant Alum sulphate and Poly Aluminium Chloride (PAC

    Directory of Open Access Journals (Sweden)

    Raimon Raimon

    2017-06-01

    Full Text Available It has been investigated of the laboratory effluent treatment using coagulant Alum sulphate (AS and Poly Aluminum Chloride (PAC. This research purposes to get the best doses of coagulant in waste water treatment. Parameter focuses are Total Dissolved Solid (TDS, Fe, Mn, Cr, and Ammoniac (NH3. The result shows the Alum sulphate was more effective. The effectiveness of pollutant decrease is 58,80% of TDS, 99,14% of Fe, 98% of Cr, 77,24% of Mn, and 23,18% of Ammoniac, respectively.

  15. Methodology for the design of a PACS in a small provincial hospital.

    Science.gov (United States)

    Leehan, Joaquín Azpiroz; Cañas, Silvia Vides; Licona, Fabiola Martínez; Méndez, Miguel Cadena; Lerallut, Jean-François

    2008-01-01

    This paper describes the design and implantation issues for a Picture Archiving and Communications System (PACS) in a 60-bed provincial hospital. Considerations such as the state of the imaging equipment, preventive maintenance, use and misuse of the equipment and the difficulties regarding migration to an all-digital imaging unit are discussed, as well as the criteria for the selection of the imaging modalities. Finally a design is proposed with four imaging modalities that use open-source database and display workstations. The system is currently under evaluation for possible reproduction in as many as 60 small clinics and hospitals throughout the country.

  16. Confirmatory factor analysis of the Patient Assessment of Constipation-Symptoms (PAC-SYM) among patients with chronic constipation

    DEFF Research Database (Denmark)

    Neri, Luca; Conway, Paul Maurice; Basilisco, Guido

    2015-01-01

    BACKGROUND AND AIM: PAC-SYM is widely adopted to asses constipation severity. However, it has been validated in a small sample, few items have been included based on expert opinion and not on empirical grounds, and its factor structure has never been replicated. We aimed at evaluating the psychom......BACKGROUND AND AIM: PAC-SYM is widely adopted to asses constipation severity. However, it has been validated in a small sample, few items have been included based on expert opinion and not on empirical grounds, and its factor structure has never been replicated. We aimed at evaluating...... the psychometric properties of PAC-SYM in patients with chronic constipation. METHODS: We enrolled 2,203 outpatients with chronic constipation in two waves. We used wave I sample to test the psychometric properties of the PAC-SYM and wave II sample to cross-validate its factor structure, to assess criterion.......28-0.45), discrimination across Rome III criteria for functional constipation and abdominal pain, and responsiveness to clinical change (β = -0.49; ω (2) = 0.25). M:PAC-SYM minimal clinically important difference was 0.24. CONCLUSION: Our analysis shows that the rectal domain may not represent a relevant cluster...

  17. Adsorption of selected emerging contaminants onto PAC and GAC: Equilibrium isotherms, kinetics, and effect of the water matrix.

    Science.gov (United States)

    Real, Francisco J; Benitez, F Javier; Acero, Juan L; Casas, Francisco

    2017-07-03

    The removal of three emerging contaminants (ECs) (amitriptyline hydrochloride (AH), methyl salicylate (MS) and 2-phenoxyethanol (PE)) dissolved in several water matrices by means of their adsorption onto powdered activated carbon (PAC) and granular activated carbon (GAC) has been investigated. When dissolved in ultrapure water, adsorption of the ECs followed the trend of AH > MS > PE, with a positive effect of the adsorbent dose. According to the analysis of the adsorption isotherms and adsorption kinetics, PAC showed strongly higher adsorption efficiency in both capacity and velocity of the adsorption, in agreement with its higher mesoporosity. Equilibrium isotherm data were fitted by Langmuir and Freundlich models. Pseudo-second order kinetics modeled very successfully the adsorption process. Finally, the effect of the presence of dissolved organic matter (DOM) in the water matrices (ultrapure water, surface water and two effluents from wastewater treatment plants) on the adsorption of the selected ECs onto PAC was established, as well as its performance on the removal of water quality parameters. Results show a negative effect of the DOM content on the adsorption efficiency. Over 50% of organic matter was removed with high PAC doses, revealing that adsorption onto PAC is an effective technology to remove both micro-pollutants and DOM from water matrices.

  18. Studies of time dependence of fields in TEVATRON superconducting dipole magnets

    International Nuclear Information System (INIS)

    Hanft, R.W.; Brown, B.C.; Herrup, D.A.; Lamm, M.J.; McInturff, A.D.; Syphers, M.J.

    1988-01-01

    The time variation in the magnetic field of a model Tevatron dipole magnet at constant excitation current has been studied. Variations in symmetry allowed harmonic components over long time ranges show a log t behavior indicative of ''flux creep.'' Both short time range and long time range behavior depend in a detailed way on the excitation history. Similar effects are seen in the remnant fields present in full-scale Tevatron dipoles following current ramping. Both magnitudes and time dependences are observed to depend on details for the ramps, such as ramp rate, flattop duration, and number of ramps. In a few magnets, variations are also seen in symmetry unallowed harmonics. 9 refs., 10 figs

  19. Co-occurring alcohol and cocaine dependence: recent findings from clinical and field studies.

    Science.gov (United States)

    Flanner, B A; Morgenstern, Jon; McKay, James; Wechsberg, Wendee M; Litten, R Z

    2004-06-01

    This article represents the proceedings of a symposium held at the 2003 annual meeting of the Research Society on Alcoholism in Ft. Lauderdale, FL. The organizer and chair was Barbara A. Flannery, and the discussant was Raye Z. Litten. The presentations were (1) Examining treatment trajectories of alcohol and cocaine dependent patients, by Jon Morgenstern; (2) Outcomes of alcoholics with and without cocaine dependence in a continuing care study, by James R. McKay; (3) Characteristics of non-treatment seeking cocaine and alcohol dependent African Americans, by Barbara A. Flannery; and (4) Cocaine and alcohol use among sex workers in South Africa, by Wendee M. Wechsberg. Copyright 2004 Research Society on Alcoholism

  20. Kinetic study of time-dependent fixation of U{sup VI} on biochar

    Energy Technology Data Exchange (ETDEWEB)

    Ashry, A. [Division of Agricultural and Environmental Sciences, School of Biosciences, University of Nottingham, Sutton Bonington, Leicestershire LE12 5RD (United Kingdom); Radiation Protection Department, Nuclear Research Centre, Egyptian Atomic Energy Authority, Cairo (Egypt); Bailey, E.H., E-mail: liz.bailey@nottingham.ac.uk [Division of Agricultural and Environmental Sciences, School of Biosciences, University of Nottingham, Sutton Bonington, Leicestershire LE12 5RD (United Kingdom); Chenery, S.R.N. [British Geological Survey, Nicker Hill, Keyworth, Nottingham NG12 5GG (United Kingdom); Young, S.D. [Division of Agricultural and Environmental Sciences, School of Biosciences, University of Nottingham, Sutton Bonington, Leicestershire LE12 5RD (United Kingdom)

    2016-12-15

    Biochar, a by-product from the production of biofuel and syngas by gasification, was tested as a material for adsorption and fixation of U{sup VI} from aqueous solutions. A batch experiment was conducted to study the factors that influence the adsorption and time-dependent fixation on biochar at 20 °C, including pH, initial concentration of U{sup VI} and contact time. Uranium (U{sup VI}) adsorption was highly dependent on pH but adsorption on biochar was high over a wide range of pH values, from 4.5 to 9.0, and adsorption strength was time-dependent over several days. The experimental data for pH > 7 were most effectively modelled using a Freundlich adsorption isotherm coupled to a reversible first order kinetic equation to describe the time-dependent fixation of U{sup VI} within the biochar structure. Desorption experiments showed that U{sup VI} was only sparingly desorbable from the biochar with time and isotopic dilution with {sup 233}U{sup VI} confirmed the low, or time-dependent, lability of adsorbed {sup 238}U{sup VI}. Below pH 7 the adsorption isotherm trend suggested precipitation, rather than true adsorption, may occur. However, across all pH values (4.5-9) measured saturation indices suggested precipitation was possible: autunite below pH 6.5 and either swartzite, liebigite or bayleyite above pH 6.5.

  1. Kinetic study of time-dependent fixation of UVI on biochar

    International Nuclear Information System (INIS)

    Ashry, A.; Bailey, E.H.; Chenery, S.R.N.; Young, S.D.

    2016-01-01

    Biochar, a by-product from the production of biofuel and syngas by gasification, was tested as a material for adsorption and fixation of U VI from aqueous solutions. A batch experiment was conducted to study the factors that influence the adsorption and time-dependent fixation on biochar at 20 °C, including pH, initial concentration of U VI and contact time. Uranium (U VI ) adsorption was highly dependent on pH but adsorption on biochar was high over a wide range of pH values, from 4.5 to 9.0, and adsorption strength was time-dependent over several days. The experimental data for pH > 7 were most effectively modelled using a Freundlich adsorption isotherm coupled to a reversible first order kinetic equation to describe the time-dependent fixation of U VI within the biochar structure. Desorption experiments showed that U VI was only sparingly desorbable from the biochar with time and isotopic dilution with 233 U VI confirmed the low, or time-dependent, lability of adsorbed 238 U VI . Below pH 7 the adsorption isotherm trend suggested precipitation, rather than true adsorption, may occur. However, across all pH values (4.5-9) measured saturation indices suggested precipitation was possible: autunite below pH 6.5 and either swartzite, liebigite or bayleyite above pH 6.5.

  2. Mode of Delivery in Drug-Dependent Pregnant Women: A Case Control Study.

    Science.gov (United States)

    Neves, Ana Raquel; Neves, Fabiane; Santos Silva, Isabel; Almeida, Maria do Céu; Monteiro, Pitorra

    2017-01-01

    Objective . To determine the contribution of drug use during pregnancy to the route of delivery. Methods . A case-control study was conducted at a hospital in Coimbra, Portugal, between 2001 and 2014. Drug-dependent pregnant women ( n = 236) were compared with a control group of low risk women ( n = 228) in terms of maternal characteristics, obstetric history, pregnancy complications, and labor details. Factors that influenced the mode of delivery were determined. Statistical analysis was performed with SPSS v. 23.0 (IBM Corp.). p values Drug-dependent women presented a lower rate of cesarean delivery (18.2 versus 28.9%, p = 0.006). After adjusting for the factors that were significantly related to the mode of delivery, drug dependency influenced the rate of cesarean section ( β = 0.567; 95% CI = 0.328-0.980). Within the drug-dependent group, the mode of delivery was significantly related to previous cesarean or vaginal delivery ( p = 0.008 and p drug, route of administration, or substitution maintenance therapy. Conclusions . The drug-dependent group presented a significantly higher rate of vaginal delivery. However, this was not associated with the behavioral factors analyzed. We hypothesize that other social and psychological factors might explain this difference.

  3. An observational study of buprenorphine treatment of the prescription opioid dependent pain patient.

    Science.gov (United States)

    Streltzer, Jon; Davidson, Raymond; Goebert, Deborah

    2015-06-01

    In some countries, particularly the United States and Canada, there has been a growing problem of opioid dependence associated with the treatment of chronic pain. Controversy exists regarding the efficacy and safety of opioid therapy, particularly in high doses for extended periods of time. This study reports on the outcome of chronic pain patients treated with buprenorphine in an outpatient psychiatric consultation clinic. Forty three consecutive outpatient clinic chronic pain patients with a DSM-IV diagnosis of opioid dependence and treated with buprenorphine during a 3-year period were monitored for follow-up periods of up to 5 years. All subjects were dependent on drugs prescribed for pain and were divided into two groups: those who had a history of abuse of alcohol or drugs and those who did not Historical, physical, demographic, and outcome data were collected. The majority of patients were male, not working, and between the ages of 45-60. Follow-up revealed that treatment with buprenorphine was effective. Most patients had improved pain with treatment of the opioid dependence. There were no differences between those with or without a history of substance abuse. Patients often improved with much less preoccupation with pain, expressing great satisfaction with buprenorphine treatment. Buprenorphine is an effective tool when treating the opioid-dependent chronic pain patient. © American Academy of Addiction Psychiatry.

  4. An experimental field study of delayed density dependence in natural populations of Aedes albopictus.

    Directory of Open Access Journals (Sweden)

    Rachael K Walsh

    Full Text Available Aedes albopictus, a species known to transmit dengue and chikungunya viruses, is primarily a container-inhabiting mosquito. The potential for pathogen transmission by Ae. albopictus has increased our need to understand its ecology and population dynamics. Two parameters that we know little about are the impact of direct density-dependence and delayed density-dependence in the larval stage. The present study uses a manipulative experimental design, under field conditions, to understand the impact of delayed density dependence in a natural population of Ae. albopictus in Raleigh, North Carolina. Twenty liter buckets, divided in half prior to experimentation, placed in the field accumulated rainwater and detritus, providing oviposition and larval production sites for natural populations of Ae. albopictus. Two treatments, a larvae present and larvae absent treatment, were produced in each bucket. After five weeks all larvae were removed from both treatments and the buckets were covered with fine mesh cloth. Equal numbers of first instars were added to both treatments in every bucket. Pupae were collected daily and adults were frozen as they emerged. We found a significant impact of delayed density-dependence on larval survival, development time and adult body size in containers with high larval densities. Our results indicate that delayed density-dependence will have negative impacts on the mosquito population when larval densities are high enough to deplete accessible nutrients faster than the rate of natural food accumulation.

  5. Mode of Delivery in Drug-Dependent Pregnant Women: A Case Control Study

    Directory of Open Access Journals (Sweden)

    Ana Raquel Neves

    2017-01-01

    Full Text Available Objective. To determine the contribution of drug use during pregnancy to the route of delivery. Methods. A case-control study was conducted at a hospital in Coimbra, Portugal, between 2001 and 2014. Drug-dependent pregnant women (n=236 were compared with a control group of low risk women (n=228 in terms of maternal characteristics, obstetric history, pregnancy complications, and labor details. Factors that influenced the mode of delivery were determined. Statistical analysis was performed with SPSS v. 23.0 (IBM Corp.. p values < 0.05 were considered statistically significant. Results. Drug-dependent women presented a lower rate of cesarean delivery (18.2 versus 28.9%, p=0.006. After adjusting for the factors that were significantly related to the mode of delivery, drug dependency influenced the rate of cesarean section (β=0.567; 95% CI = 0.328–0.980. Within the drug-dependent group, the mode of delivery was significantly related to previous cesarean or vaginal delivery (p=0.008 and p<0.001, resp. and fetal presentation (p<0.001, but not with the type of drug, route of administration, or substitution maintenance therapy. Conclusions. The drug-dependent group presented a significantly higher rate of vaginal delivery. However, this was not associated with the behavioral factors analyzed. We hypothesize that other social and psychological factors might explain this difference.

  6. Rapid Analysis of Carbohydrates in Bioprocess Samples: An Evaluation of the CarboPac SA10 for HPAE-PAD Analysis by Interlaboratory Comparison

    Energy Technology Data Exchange (ETDEWEB)

    Sevcik, R. S.; Hyman, D. A.; Basumallich, L.; Scarlata, C. J.; Rohrer, J.; Chambliss, C. K.

    2013-01-01

    A technique for carbohydrate analysis for bioprocess samples has been developed, providing reduced analysis time compared to current practice in the biofuels R&D community. The Thermofisher CarboPac SA10 anion-exchange column enables isocratic separation of monosaccharides, sucrose and cellobiose in approximately 7 minutes. Additionally, use of a low-volume (0.2 mL) injection valve in combination with a high-volume detection cell minimizes the extent of sample dilution required to bring sugar concentrations into the linear range of the pulsed amperometric detector (PAD). Three laboratories, representing academia, industry, and government, participated in an interlaboratory study which analyzed twenty-one opportunistic samples representing biomass pretreatment, enzymatic saccharification, and fermentation samples. The technique's robustness, linearity, and interlaboratory reproducibility were evaluated and showed excellent-to-acceptable characteristics. Additionally, quantitation by the CarboPac SA10/PAD was compared with the current practice method utilizing a HPX-87P/RID. While these two methods showed good agreement a statistical comparison found significant quantitation difference between them, highlighting the difference between selective and universal detection modes.

  7. DNA bipedal motor walking dynamics: an experimental and theoretical study of the dependency on step size.

    Science.gov (United States)

    Khara, Dinesh C; Schreck, John S; Tomov, Toma E; Berger, Yaron; Ouldridge, Thomas E; Doye, Jonathan P K; Nir, Eyal

    2018-02-16

    We present a detailed coarse-grained computer simulation and single molecule fluorescence study of the walking dynamics and mechanism of a DNA bipedal motor striding on a DNA origami. In particular, we study the dependency of the walking efficiency and stepping kinetics on step size. The simulations accurately capture and explain three different experimental observations. These include a description of the maximum possible step size, a decrease in the walking efficiency over short distances and a dependency of the efficiency on the walking direction with respect to the origami track. The former two observations were not expected and are non-trivial. Based on this study, we suggest three design modifications to improve future DNA walkers. Our study demonstrates the ability of the oxDNA model to resolve the dynamics of complex DNA machines, and its usefulness as an engineering tool for the design of DNA machines that operate in the three spatial dimensions.

  8. Design and implementation of a web-based data grid management system for enterprise PACS backup and disaster recovery

    Science.gov (United States)

    Zhou, Zheng; Ma, Kevin; Talini, Elisa; Documet, Jorge; Lee, Jasper; Liu, Brent

    2007-03-01

    A cross-continental Data Grid infrastructure has been developed at the Image Processing and Informatics (IPI) research laboratory as a fault-tolerant image data backup and disaster recovery solution for Enterprise PACS. The Data Grid stores multiple copies of the imaging studies as well as the metadata, such as patient and study information, in geographically distributed computers and storage devices involving three different continents: America, Asia and Europe. This effectively prevents loss of image data and accelerates data recovery in the case of disaster. However, the lack of centralized management system makes the administration of the current Data Grid difficult. Three major challenges exist in current Data Grid management: 1. No single user interface to access and administrate each geographically separate component; 2. No graphical user interface available, resulting in command-line-based administration; 3. No single sign-on access to the Data Grid; administrators have to log into every Grid component with different corresponding user names/passwords. In this paper we are presenting a prototype of a unique web-based access interface for both Data Grid administrators and users. The interface has been designed to be user-friendly; it provides necessary instruments to constantly monitor the current status of the Data Grid components and their contents from any locations, contributing to longer system up-time.

  9. The role of the CI expansion length in time-dependent studies

    Science.gov (United States)

    Ulusoy, Inga S.; Stewart, Zachary; Wilson, Angela K.

    2018-01-01

    With the recent advances in experimental attosecond science, theoretical predictions of electron dynamics can now be validated against experiment. Time-dependent studies of the electron motion in molecules can be used to obtain information about electronic transitions and the interaction of the electrons with electromagnetic fields. Often, these approaches rely on single-excited wave functions. Presented here is a first attempt to evaluate the accuracy of the time-dependent configuration interaction method so that the optimal representation of the electronic wave function for time-dependent studies can be assessed. A quantifier is determined that can aid in finding this optimal representation. The approach is demonstrated on a variety of molecules that include both localized and intramolecular charge transfer electron excitations. Observables including excitation energies, dipole moments, strengths, and static polarizabilities are obtained from time-independent and time-dependent calculations and are compared to experimental data. In this way, a rigorous routine is developed by which the reliability and accuracy of the CI wave function can be assessed and which represents a first step to a more quantitative description of electron dynamics in molecules.

  10. Personality characteristics and psychological distress associated with primary exercise dependence: an exploratory study.

    Science.gov (United States)

    Grandi, Silvana; Clementi, Cecilia; Guidi, Jenny; Benassi, Mariagrazia; Tossani, Eliana

    2011-09-30

    The aim of this study was to assess personality characteristics and psychological distress associated with primary exercise dependence (ExeDepI) in a mixed gender sample. A cross-sectional study was carried out with adult habitual physical exercisers. A total of 79 participants voluntarily completed a package of self-report questionnaires including the Exercise Dependence Questionnaire (EDQ), the Eating Disorder Inventory II (EDI-2), the Temperament and Character Inventory (TCI), the Attitude Toward Self scale (ATS), and the Symptom Questionnaire (SQ). Significant differences were found on the EDQ exercise for weight control subscale with regard to gender, as well as on the EDI-2 total score and five of its subscales, with higher scores for females compared to males. Participants reporting primary exercise dependence (N=32) were more likely to present with disordered eating patterns than controls (N=47). They also showed higher levels of harm avoidance and persistence on the TCI, but lower self-directness and less mature character. Furthermore, ExeDepI group scored higher on the ATS dysmorphophobia subscale, as well as on the anxiety and hostility subscales of the SQ compared to the control group. These findings provide support to the idea that primary exercise dependence can be considered as a clinical syndrome associated with certain personality characteristics and psychological symptoms that might be accurately assessed in clinical settings. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  11. Study of hydrodynamic behaviour of large bearings depending on the viscosity of the lubricant

    Directory of Open Access Journals (Sweden)

    Barabas Sorin

    2017-01-01

    Full Text Available The research refers to study of hydrodynamic behavior of large bearings equipped with automatic lubrication system, where the liquid used may have a viscosity with variable values depending on the temperature or depending on the additive used. The introduction of additives with nanoparticles causes modification of viscosity and a significant reduction of friction coefficient. This study establishes a direct link between the friction, viscosity and tensions that occur in the contact area. Experimental studies confirm improving tribological properties of the contact area between the bearing rollers and raceways, through attracting nanoparticles on surfaces in contact and reducing friction coefficient. Accomplished finite element analysis showed decrease of the contact stresses, therefore decrease of the wear and increase the life of the bearing. Research has concluded that influencing viscosity and friction coefficient of lubricant can result in reducing wear of the bearing components, as well as increase the lifetime of bearing.

  12. Angular-dependent Raman study of a- and s-plane InN

    Energy Technology Data Exchange (ETDEWEB)

    Filintoglou, K.; Katsikini, M., E-mail: katsiki@auth.gr; Arvanitidis, J.; Lotsari, A.; Dimitrakopulos, G. P.; Vouroutzis, N.; Ves, S. [School of Physics, Aristotle University of Thessaloniki, 54124 Thessaloniki (Greece); Christofilos, D.; Kourouklis, G. A. [Chemical Engineering Department, Aristotle University of Thessaloniki, 54124 Thessaloniki (Greece); Ajagunna, A. O.; Georgakilas, A. [Microelectronics Research Group, Department of Physics, University of Crete, P.O. Box 2208, GR 71003 Heraklion, Greece and IESL, FORTH, P.O. Box 1385, GR 71110 Heraklion (Greece); Zoumakis, N. [Department of Food Technology, Technological Educational Institute of Thessaloniki, 57400 Sindos (Greece)

    2015-02-21

    Angular-dependent polarized Raman spectroscopy was utilized to study nonpolar a-plane (11{sup ¯}20) and semipolar s-plane (101{sup ¯}1) InN epilayers. The intensity dependence of the Raman peaks assigned to the vibrational modes A{sub 1}(TO), E{sub 1}(TO), and E{sub 2}{sup h} on the angle ψ that corresponds to rotation around the growth axis, is very well reproduced by using expressions taking into account the corresponding Raman tensors and the experimental geometry, providing thus a reliable technique towards assessing the sample quality. The s- and a-plane InN epilayers grown on nitridated r-plane sapphire (Al{sub 2}O{sub 3}) exhibit good crystalline quality as deduced from the excellent fitting of the experimental angle-dependent peak intensities to the theoretical expressions as well as from the small width of the Raman peaks. On the contrary, in the case of the s-plane epilayer grown on non-nitridated r-plane sapphire, fitting of the angular dependence is much worse and can be modeled only by considering the presence of two structural modifications, rotated so as their c-axes are almost perpendicular to each other. Although the presence of the second variant is verified by transmission electron and atomic force microscopies, angular dependent Raman spectroscopy offers a non-destructive and quick way for its quantification. Rapid thermal annealing of this sample did not affect the angular dependence of the peak intensities. The shift of the E{sub 1}(TO) and E{sub 2}{sup h} Raman peaks was used for the estimation of the strain state of the samples.

  13. Using indicators and models for an ecosystem approach to fisheries and aquaculture management: the anchovy fishery and Pacific oyster culture in Chile: case studies Aplicación de indicadores y modelos para un enfoque ecosistémico de la pesca y la acuicultura: pesquería de anchoveta y cultivo de ostra del Pacífico en Chile: casos de estudio

    Directory of Open Access Journals (Sweden)

    Claudio Silva

    2012-11-01

    Full Text Available This study illustrate the use of indicators and models to support the Ecosystem Approach to Fisheries and Aquaculture management using two case studies in Chile: prediction of environmental variability effects upon anchovy (Engraulis ringens fishery of northern Chile and prediction of suitable sites and carrying capacity of Pacific oyster (Crassostrea gigas culture using FARM and geographic information system (GIS models in the Valdivia estuary. A three stage approach was applied: Stage 1 considers spatiotemporal ecosystem indicators (fisheries, aquaculture, environmental, and regulatory, Stage 2 uses statistical relationships between indicators, GIS, and other simulation models (e.g., artificial neural networks and FARM of environment-resources interaction, and Stage 3 is the analysis and validation of models outputs. The methodology illustrates how indicators and models may be used to assist decision-makers in developing an ecosystem approach to fisheries and aquaculture. The application of these approaches provides an integrative methodology for abundance prediction of anchovy and site selection for shellfish aquaculture, despite limitations in the available data.Este trabajo muestra el uso de indicadores y modelos para apoyar la aplicación del enfoque ecosistémico en la gestión de la pesca y la acuicultura, mediante dos casos de estudios en Chile: predicción de los efectos de la variabilidad ambiental en la pesquería de anchoveta (Engraulis ringens en la zona norte de Chile y la predicción de sitios aptos y capacidad de carga para el cultivo de la ostra del Pacífico (Crassostrea gigas en el estuario de Valdivia. Se aplicó un enfoque metodológico de tres etapas: etapa 1 considera indicadores espacio-temporales del ecosistema (pesca, acuicultura, medio ambiente y legislación; etapa 2 utiliza relaciones estadísticas entre los indicadores, funciones de SIG (Sistemas de Información Geográfica, y otros modelos de simulación (Redes

  14. Design and implementation of an integrated PACS workstation in the ICU

    Science.gov (United States)

    Nahmias, Claude; Kenyon, David B.; Tan, Lianne; Coblentz, Craig L.

    1997-05-01

    A PACS workstation grants to Intensive Care Unit (ICU) staff direct and convenient access to radiographic images. The special requirements of access to, and display of radiographic images in the ICU were considered in the design of a PACS workstation for the ICU. and implemented as an extension of the Image Management and Communication Systems (IMACS) network at McMaster University Medical Center. The majority of radiographic exams performed in the ICU are portable chest x-ray exams. These images are processed by Computed Radiography and immediately directed towards online storage on the ICU workstation's local disk. Our image display software interface for the workstation was specially designed for the ICU to provide patient data entry, fast thumbnail viewing of all images for the occupied beds, full resolution display, and image manipulation, all in a user- friendly graphical interface. The workstation has been in place in the ICU for 1.5 years. While there are upgrades still to be made to the computer and monitors, and changes to the workflow to be made, the workstation has established itself as a n important part of the ICU.

  15. Asia- Pacífico en la Estrategia de Seguridad Nacional 2013

    Directory of Open Access Journals (Sweden)

    Gracia Abad

    2014-05-01

    Full Text Available A pesar de que la Estrategia de Seguridad Nacional incluye Asia-Pacífico entre los entornos estratégicos considerados como prioritarios para España, un análisis más pausado del documento revela que, en realidad, la importancia que se otorga a la región no es demasiado elevada. Tal aproximación es sorprendente si tenemos en cuenta no sólo el creciente papel de Asia-Pacífico en los asuntos internacionales, sino la cada vez mayor atención a la región de otros actores, entre los que cabe mencionar a los Estados Unidos, pero también a algunos los principales miembros de la Unión Europea. Esa baja prioridad asignada a la región, unida a una definición excesivamente vaga tanto de los posibles desafíos para nuestra seguridad provenientes de esa región, como de las acciones que se podrían poner en marcha para atenderlos, hacen que el documento diste de lo que sería necesario en lo que respecta a este ámbito geográfico.

  16. Distributed PACS using distributed file system with hierarchical meta data servers.

    Science.gov (United States)

    Hiroyasu, Tomoyuki; Minamitani, Yoshiyuki; Miki, Mitsunori; Yokouchi, Hisatake; Yoshimi, Masato

    2012-01-01

    In this research, we propose a new distributed PACS (Picture Archiving and Communication Systems) which is available to integrate several PACSs that exist in each medical institution. The conventional PACS controls DICOM file into one data-base. On the other hand, in the proposed system, DICOM file is separated into meta data and image data and those are stored individually. Using this mechanism, since file is not always accessed the entire data, some operations such as finding files, changing titles, and so on can be performed in high-speed. At the same time, as distributed file system is utilized, accessing image files can also achieve high-speed access and high fault tolerant. The introduced system has a more significant point. That is the simplicity to integrate several PACSs. In the proposed system, only the meta data servers are integrated and integrated system can be constructed. This system also has the scalability of file access with along to the number of file numbers and file sizes. On the other hand, because meta-data server is integrated, the meta data server is the weakness of this system. To solve this defect, hieratical meta data servers are introduced. Because of this mechanism, not only fault--tolerant ability is increased but scalability of file access is also increased. To discuss the proposed system, the prototype system using Gfarm was implemented. For evaluating the implemented system, file search operating time of Gfarm and NFS were compared.

  17. Himage PACS: a new approach to storage, integration, and distribution of cardiologic images

    Science.gov (United States)

    Costa, Carlos M.; Silva, Augusto; Oliveira, Jose L.; Ribeiro, Vasco G.; Ribeiro, Jose

    2004-04-01

    This paper presents a Cardiology oriented information system that provides permanent availability of all clinical history, including alphanumeric and image data, with time and cost-effective transmission (reduced download time), without loss of image diagnosis quality and based on a Web Multimedia Integrated Access Interface. This implies the integration of HIS and PACS in a unique access interface, providing on-line and fast access to authorized healthcare professionals. The benefits obtained from the HIS-PACS integration and from the availability of all historical patient data are unquestionable to practitioners but also to the patients. Moreover, the system includes a telematic platform capable of establishing cooperative telemedicine sessions where our most impressive utilization is a transcontinental work platform for cardiovascular ultrasound. The key point of our approach starts with the construction of a DICOM private transfer syntax that is prepared to support any video encoder installed on a Windows-based station. With this structure it is possible to select the best encoder to a specific modality and work scenario. Good trade-off between compression ratio and diagnostic quality, low network traffic load, backup facilities and data portability are other achievements of this system.

  18. Automation of PacBio SMRTbell NGS library preparation for bacterial genome sequencing.

    Science.gov (United States)

    Kong, Nguyet; Ng, Whitney; Thao, Kao; Agulto, Regina; Weis, Allison; Kim, Kristi Spittle; Korlach, Jonas; Hickey, Luke; Kelly, Lenore; Lappin, Stephen; Weimer, Bart C

    2017-01-01

    The PacBio RS II provides for single molecule, real-time DNA technology to sequence genomes and detect DNA modifications. The starting point for high-quality sequence production is high molecular weight genomic DNA. To automate the library preparation process, there must be high-throughput methods in place to assess the genomic DNA, to ensure the size and amounts of the sheared DNA fragments and final library. The library construction automation was accomplished using the Agilent NGS workstation with Bravo accessories for heating, shaking, cooling, and magnetic bead manipulations for template purification. The quality control methods from gDNA input to final library using the Agilent Bioanalyzer System and Agilent TapeStation System were evaluated. Automated protocols of PacBio 10 kb library preparation produced libraries with similar technical performance to those generated manually. The TapeStation System proved to be a reliable method that could be used in a 96-well plate format to QC the DNA equivalent to the standard Bioanalyzer System results. The DNA Integrity Number that is calculated in the TapeStation System software upon analysis of genomic DNA is quite helpful to assure that the starting genomic DNA is not degraded. In this respect, the gDNA assay on the TapeStation System is preferable to the DNA 12000 assay on the Bioanalyzer System, which cannot run genomic DNA, nor can the Bioanalyzer work directly from the 96-well plates.

  19. Implementation of system intelligence in a 3-tier telemedicine/PACS hierarchical storage management system

    Science.gov (United States)

    Chao, Woodrew; Ho, Bruce K. T.; Chao, John T.; Sadri, Reza M.; Huang, Lu J.; Taira, Ricky K.

    1995-05-01

    Our tele-medicine/PACS archive system is based on a three-tier distributed hierarchical architecture, including magnetic disk farms, optical jukebox, and tape jukebox sub-systems. The hierarchical storage management (HSM) architecture, built around a low cost high performance platform [personal computers (PC) and Microsoft Windows NT], presents a very scaleable and distributed solution ideal for meeting the needs of client/server environments such as tele-medicine, tele-radiology, and PACS. These image based systems typically require storage capacities mirroring those of film based technology (multi-terabyte with 10+ years storage) and patient data retrieval times at near on-line performance as demanded by radiologists. With the scaleable architecture, storage requirements can be easily configured to meet the needs of the small clinic (multi-gigabyte) to those of a major hospital (multi-terabyte). The patient data retrieval performance requirement was achieved by employing system intelligence to manage migration and caching of archived data. Relevant information from HIS/RIS triggers prefetching of data whenever possible based on simple rules. System intelligence embedded in the migration manger allows the clustering of patient data onto a single tape during data migration from optical to tape medium. Clustering of patient data on the same tape eliminates multiple tape loading and associated seek time during patient data retrieval. Optimal tape performance can then be achieved by utilizing the tape drives high performance data streaming capabilities thereby reducing typical data retrieval delays associated with streaming tape devices.

  20. Distributed architecture for image archival in a hospital-wide PACS

    Science.gov (United States)

    Ratib, Osman M.; Ligier, Yves; Funk, Matthieu; Vurlod, Jean-Francois; Trayser, Gerhard; Scherrer, Jean-Raoul

    1992-07-01

    A hospital-wide PACS project is currently under development at the University Hospital of Geneva. This system is based on an open architecture regrouping equipment from multiple vendors in a distributed topology. The image archival is organized in multiple locations geographically distributed in the hospital. These regional archives are logically linked together to provide a virtual access to all images generated from different imaging modalities. A standardized image storage format called PAPYRUS was designed based on ACR-NEMA definitions to unify the image storage and display functionalities. The PACS database is also fully integrated with the concurrent RIS and HIS. Images from different archive servers are hierarchically distributed to other temporary storage space on regional display servers. Clusters of workstations are regrouped around these local servers allowing a more efficient access to the images on local subnetworks. Special software tools were designed for the management of image distribution and maintenance of local storage space. In addition to pre- programmed and rule-based distribution of images to regional display servers, special requests can be posted by the users to initiate the transfer of additional image files from the archive servers to their local display server. The design and implementation of the system will be presented and methodological issues will be discussed. Results from preliminary simulations performed prior to the final implementation will be presented and compared to real measurements performed on the system in operation. The advantages and difficulties of implementing a distributed hierarchical storage of images will be reported.