WorldWideScience

Sample records for density profiles obtained

  1. Flow Rate of Particles through Apertures Obtained from Self-Similar Density and Velocity Profiles

    Science.gov (United States)

    Janda, Alvaro; Zuriguel, Iker; Maza, Diego

    2012-06-01

    “Beverloo’s law” is considered as the standard expression to estimate the flow rate of particles through apertures. This relation was obtained by simple dimensional analysis and includes empirical parameters whose physical meaning is poorly justified. In this Letter, we study the density and velocity profiles in the flow of particles through an aperture. We find that, for the whole range of apertures studied, both profiles are self-similar. Hence, by means of the functionality obtained for them the mass flow rate is calculated. The comparison of this expression with the Beverloo’s one reveals some differences which are crucial to understanding the mechanism that governs the flow of particles through orifices.

  2. Assessment studies on the inversion of satellite to satellite electron content to obtain electron density profiles in the ionosphere

    CERN Document Server

    Hochegger, G P

    2000-01-01

    The electron content data, obtained by satellite-to-satellite occultations of radio signals can lead to height profiles of electron density by discrete inversion. Since there is no possibility to verify such profiles by means of other measurements (practically never measurements at the same time and same location) it was necessary to simulate occultation scenarios by means of an ionosphere model to obtain a large number of comparisons sufficient for investigations on a statistical basis. The obtained electron contents were inverted and compared with electron density height profiles, obtained with the same ionospheric model for the occultation point. The differences between these profiles were investigated (difference between the F2-peak maxima, the height of the maxima, the shape of the topside and bottom side ionosphere). Since simulations were done for chosen locations (250 randomly spread on the globe) for every month and every second hour and for two solar activity levels (HSA and LSA), a whole year was '...

  3. Flow rate of particles through apertures obtained from self-similar density and velocity profiles

    OpenAIRE

    2012-01-01

    ‘‘Beverloo’s law’’ is considered as the standard expression to estimate the flow rate of particles through apertures. This relation was obtained by simple dimensional analysis and includes empirical parameters whose physical meaning is poorly justified. In this Letter, we study the density and velocity profiles in the flow of particles through an aperture. We find that, for the whole range of apertures studied, both profiles are self-similar. Hence, by means of the functionality obtained for the...

  4. Method to obtain absolute impurity density profiles combining charge exchange and beam emission spectroscopy without absolute intensity calibrationa)

    Science.gov (United States)

    Kappatou, A.; Jaspers, R. J. E.; Delabie, E.; Marchuk, O.; Biel, W.; Jakobs, M. A.

    2012-10-01

    Investigation of impurity transport properties in tokamak plasmas is essential and a diagnostic that can provide information on the impurity content is required. Combining charge exchange recombination spectroscopy (CXRS) and beam emission spectroscopy (BES), absolute radial profiles of impurity densities can be obtained from the CXRS and BES intensities, electron density and CXRS and BES emission rates, without requiring any absolute calibration of the spectra. The technique is demonstrated here with absolute impurity density radial profiles obtained in TEXTOR plasmas, using a high efficiency charge exchange spectrometer with high etendue, that measures the CXRS and BES spectra along the same lines-of-sight, offering an additional advantage for the determination of absolute impurity densities.

  5. Method to obtain absolute impurity density profiles combining charge exchange and beam emission spectroscopy without absolute intensity calibration

    Energy Technology Data Exchange (ETDEWEB)

    Kappatou, A.; Delabie, E. [FOM Institute DIFFER - Dutch Institute for Fundamental Energy Research, Association EURATOM-FOM, 3430 BE Nieuwegein (Netherlands); Jaspers, R. J. E.; Jakobs, M. A. [Science and Technology of Nuclear Fusion, Eindhoven University of Technology, 5600 MB Eindhoven (Netherlands); Marchuk, O.; Biel, W. [Institute for Energy and Climate Research, Forschungszentrum Julich GmbH, Trilateral Euregio Cluster, 52425 Julich (Germany)

    2012-10-15

    Investigation of impurity transport properties in tokamak plasmas is essential and a diagnostic that can provide information on the impurity content is required. Combining charge exchange recombination spectroscopy (CXRS) and beam emission spectroscopy (BES), absolute radial profiles of impurity densities can be obtained from the CXRS and BES intensities, electron density and CXRS and BES emission rates, without requiring any absolute calibration of the spectra. The technique is demonstrated here with absolute impurity density radial profiles obtained in TEXTOR plasmas, using a high efficiency charge exchange spectrometer with high etendue, that measures the CXRS and BES spectra along the same lines-of-sight, offering an additional advantage for the determination of absolute impurity densities.

  6. Comparison of high latitude electron density profiles obtained with the GPS radio occultation technique and EISCAT measurements

    Directory of Open Access Journals (Sweden)

    C. Stolle

    2004-06-01

    Full Text Available To obtain a comprehensive view on high latitude processes by applying different observation techniques, the SIRCUS campaign was initiated in 2001/2002. This paper compares electron density profiles derived from CHAMP radio occultation data and those measured with the EISCAT facility. Since ionospheric profiling with the help of space-based received GPS is a relatively new technique, validations with established independent instruments are of crucial need. We present 28 profiling events for quasi-statistical analyses, which occurred during the SIRCUS campaigns and describe some of them in more detail. We found out that the majority of profile comparisons in electron density peak value and height, as well as in TEC, lie within the error ranges of the two methods. Differences in the ionospheric quantities do not necessarily occur when the locations of the occultation and of the radar site show considerable distances. Differences are more pronounced when the ionosphere is remarkably structured.

  7. Density profiles of LCDM clusters

    CERN Document Server

    Tasitsiomi, A; Gottlöber, S; Klypin, A A; Tasitsiomi, Argyro; Kravtsov, Andrey V.; Gottloeber, Stefan; Klypin, Anatoly A.

    2004-01-01

    We analyze the mass accretion histories (MAHs) and density profiles of cluster- size halos with virial masses of 0.6-2.5x10^14/h Msun in a flat LCDM cosmology. In agreement with previous studies,we find that the concentration of the density distribution is tightly correlated with the halo's MAH and its formation redshift.During the period of fast mass growth the concentration remains approximately constant and low c_v~3-4,while during the slow accretion stages it increases with decreasing redshift as c_v~(1+z)^-1.We consider fits of three widely discussed analytic density profiles to the simulated clusters focusing on the most relaxed inner regions.We find that there is no unique best fit analytic profile for all the systems.If,however,a cluster is best fit by a particular analytic profile at z=0,the same is usually true at earlier epochs out to z~1-2.The local logarithmic slope of the density profiles at 3% of the virial radius ranges from -1.2 to -2.0,a remarkable diversity for the relatively narrow mass ra...

  8. Density profile of pyrolitic lower mantle

    Science.gov (United States)

    Sinmyo, R.; Hirose, K.; Ohishi, Y.

    2010-12-01

    Density profile of pyrolite at lower mantle high-pressure (P) and -temperature (T) conditions was investigated by using laser-heated diamond-anvil cell up to 117 GPa and 2800 K. The density was determined from chemical composition and unit-cell volume of each constituent mineral (MgSiO3-rich perovskite, ferropericlase and CaSiO3-rich perovskite). The chemical compositions of coexisting phases were analyzed by transmission electron microscope, and their volumes were obtained by in-situ X-ray diffraction measurements. To avoid extensive chemical segregation during laser-heating, sample was coated by gold that worked as a laser absorber (Sinmyo and Hirose 2010 PEPI). Results of chemical analyses show that Mg-Fe (total Fe) partitioning coefficient between MgSiO3-rich perovskite and ferropericlase [K* = (Fe*/Mg)Pv/(Fe*/Mg)Fp] is about 0.6, slightly higher than the value previously reported in the pyrolitic bulk composition (Murakami et al. 2005 GRL). The lower K* value in the previous study may be attributed to the chemical heterogeneity in the sample induced by strong temperature gradient during laser heating. The calculated density profile of pyrolite is indeed in good agreement with the PREM model within experimental errors, in contrast with the mismatch reported by the previous study (Ricolleau et al. 2009 GRL). Our results support the lower mantle has pyrolitic bulk composition, and thus it is not necessary to suppose the chemically stratification in the lower mantle.

  9. Convergence and scatter of cluster density profiles

    CERN Document Server

    Diemand, J; Stadel, J; Diemand, Juerg; Moore, Ben; Stadel, Joachim

    2004-01-01

    We present new results from a series of $\\Lambda$CDM simulations of cluster mass halos resolved with high force and mass resolution. These results are compared with recently published simulations from groups using various codes including PKDGRAV, ART, TPM, GRAPE and GADGET. Careful resolution tests show that with 25 million particles within the high resolution region we can resolve to about 0.3\\% of the virial radius and that convergence in radius is proportional to the mean interparticle separation. The density profiles of 28 high resolution clusters obtained with the different codes and from different initial conditions agree very well. The average logarithmic slope at one percent of the virial radius is $\\gamma = 1.29$ with a scatter of $\\pm 0.16$ at all radii. Over the entire resolved regions the density profiles are well fitted by a smooth function that asymptotes to a central cusp $\\rho \\propto r^{-\\gamma}$, where we find $\\gamma=1.16\\pm 0.14$ from the mean of the fits to our six highest resolution clus...

  10. Universal density profile for cosmic voids.

    Science.gov (United States)

    Hamaus, Nico; Sutter, P M; Wandelt, Benjamin D

    2014-06-27

    We present a simple empirical function for the average density profile of cosmic voids, identified via the watershed technique in ΛCDM N-body simulations. This function is universal across void size and redshift, accurately describing a large radial range of scales around void centers with only two free parameters. In analogy to halo density profiles, these parameters describe the scale radius and the central density of voids. While we initially start with a more general four-parameter model, we find two of its parameters to be redundant, as they follow linear trends with the scale radius in two distinct regimes of the void sample, separated by its compensation scale. Assuming linear theory, we derive an analytic formula for the velocity profile of voids and find an excellent agreement with the numerical data as well. In our companion paper [Sutter et al., arXiv:1309.5087 [Mon. Not. R. Astron. Soc. (to be published)

  11. Particle confinement and density profile behaviour on HL-1M

    Institute of Scientific and Technical Information of China (English)

    Jiao Yi-Ming; Zhou Yan; Deng Zhong-Chao; Ding Xuan-Tong; Liu Yong; Wang En-Yao

    2005-01-01

    In this paper the density profile behaviour and the particle confinement operation regime on HL-1M have been studied under the pellet injection (PI), supersonic molecular beam injection (SMBI), gas puffing (GP) and lower hybrid current drive experimental situations. The relationships between density profile, particle confinement time and edge safe factor have been explored. The density profile, which is measured by six-channel far-infrared ray laser interferometer has been analysed by using the peaking coefficient calculation code. Changes of the outward and inward diffusion velocities before and after the peaking of the central density profile have been calculated using the global particle balance equations. The particle confinement operation regimes have been discussed. The peaking density profile can be easily obtained under the condition of efficient fuelling. In ohmic discharges, confinement time increases as the peaking density profile factor rises, and is saturated at a critical value related to the fuelling efficiency. The particle confinement time of SMBI lies between the values of GP and PI, and its value is about 3-5 times of the energy confinement time.

  12. Density Functional Approach Based on Numerically Obtained Bridge Functional

    Institute of Scientific and Technical Information of China (English)

    ZHOUShi-Qi

    2002-01-01

    The ornstein-zenike equation is solved with the Rogers-Young approximation for bulk hard sphere fluid and Lennard-Jones fluid for several state points.Then the resulted bulk fluid radial distribution function combined with the test particle method is employed to determine numerically the function relationship of bridge functional as a function of indirect correlation function.It is found that all of the calculated points from different phase space state points for a same type of fluid collapse onto a same smooth curve.Then the numerically obtained curve is used to substitute the analytic expression of the bridge functional as a function of indirect correlation function required in the methodology [J.Chem.Phys,112(2000)8079] to determine the density distribution of non-uniform hard sphere fluid and Lennard-Jones fluid.The good agreement of theoretical predictions with the computer simulation data is obtained.The present numerical procedure incroporates the knowledge of bulk fluid radial distribution function into the constructing of the density functional approximation and makes the original methodology more accurate and more filexible for various interaction potential fluid.

  13. On the Density profile slope of Clusters of Galaxies

    CERN Document Server

    Del Popolo, A

    2012-01-01

    The present paper extends to clusters of galaxies the study of Del Popolo (2012), concerning how the baryon-dark matter (DM) interplay shapes the density profile of dwarf galaxies. Cluster density profiles are determined taking into account dynamical friction, random and ordered angular momentum and the response of dark matter halos to condensation of baryons. We find that halos containing only DM are characterized by Einasto's profiles, and that the profile flattens with increasing content of baryons, and increasing values of random angular momentum. The analytical results obtained in the first part of the paper were applied to well studied clusters whose inner profiles have slopes flatter than NFW predictions (A611, A383) or are characterized by profiles in agreement with the NFW model (MACS J1423.8+2404, RXJ1133). By using independently-measured baryonic fraction, a typical spin parameter value $\\lambda \\simeq 0.03$, and adjusting the random angular momentum, we re-obtain the mass and density profiles of t...

  14. Density Functional Approach Based on Numerically Obtained Bridge Functional

    Institute of Scientific and Technical Information of China (English)

    ZHOU Shi-Qi

    2002-01-01

    The Ornstein Zernike equation is solved with the Rogers Young approximation for bulk hard sphere fluidand Lennard-Jones fluid for several state points. Then the resulted bulk fluid radial distribution function combinedwith the test particle method is employed to determine numerically the function relationship of bridge functional as afunction of indirect correlation function. It is found that all of the calculated points from different phase space statepoints for a same type of fluid collapse onto a same smooth curve. Then the numerically obtained curve is used tosubstitute the analytic expression of the bridge functional as a function of indirect correlation function required in themethodology [J. Chem. Phys. 112 (2000) 8079] to deterrnine the density distribution of non-uniform hard spherefluid and Lennard Jones fluid. The good agreement of theoretical predictions with the computer simulation data isobtained. The present numerical procedure incorporates the knowledge of bulk fluid radial distribution function intothe constructing of the density functional approximation and makes the original methodology more accurate and moreflexible for various interaction potential fluid.

  15. Electon density profiles of the topside ionosphere

    Directory of Open Access Journals (Sweden)

    D. Bilitza

    2002-06-01

    Full Text Available The existing uncertainties about the electron density profiles in the topside ionosphere, i.e., in the height region from h m F 2 to ~ 2000 km, require the search for new data sources. The ISIS and Alouette topside sounder satellites from the sixties to the eighties recorded millions of ionograms but most were not analyzed in terms of electron density profiles. In recent years an effort started to digitize the analog recordings to prepare the ionograms for computerized analysis. As of November 2001 about 350 000 ionograms have been digitized from the original 7-track analog tapes. These data are available in binary and CDF format from the anonymous ftp site of the National Space Science Data Center. A search site and browse capabilities on CDAWeb assist the scientific usage of these data. All information and access links can be found at http://nssdc.gsfc.nasa.gov/space/isis/isis-status. html. This paper describes the ISIS data restoration effort and shows how the digital ionograms are automatically processed into electron density profiles from satellite orbit altitude (1400 km for ISIS-2 down to the F peak. Because of the large volume of data an automated processing algorithm is imperative. The TOPside Ionogram Scaler with True height algorithm TOPIST software developed for this task is successfully scaling ~ 70% of the ionograms. An «editing process» is available to manually scale the more difficult ionograms. The automated processing of the digitized ISIS ionograms is now underway, producing a much-needed database of topside electron density profiles for ionospheric modeling covering more than one solar cycle.

  16. Universal void density profiles from simulation and SDSS

    CERN Document Server

    Nadathur, S; Diego, J M; Iliev, I T; Gottlöber, S; Watson, W A; Yepes, G

    2014-01-01

    We discuss the universality and self-similarity of void density profiles, for voids in realistic mock luminous red galaxy (LRG) catalogues from the Jubilee simulation, as well as in void catalogues constructed from the SDSS LRG and Main Galaxy samples. Voids are identified using a modified version of the ZOBOV watershed transform algorithm, with additional selection cuts. We find that voids in simulation are self-similar, meaning that their average rescaled profile does not depend on the void size, or -- within the range of the simulated catalogue -- on the redshift. Comparison of the profiles obtained from simulated and real voids shows an excellent match. The profiles of real voids also show a universal behaviour over a wide range of galaxy luminosities, number densities and redshifts. This points to a fundamental property of the voids found by the watershed algorithm, which can be exploited in future studies of voids.

  17. Universal void density profiles from simulation and SDSS

    Science.gov (United States)

    Nadathur, S.; Hotchkiss, S.; Diego, J. M.; Iliev, I. T.; Gottlöber, S.; Watson, W. A.; Yepes, G.

    2016-10-01

    We discuss the universality and self-similarity of void density profiles, for voids in realistic mock luminous red galaxy (LRG) catalogues from the Jubilee simulation, as well as in void catalogues constructed from the SDSS LRG and Main Galaxy samples. Voids are identified using a modified version of the ZOBOV watershed transform algorithm, with additional selection cuts. We find that voids in simulation are self-similar, meaning that their average rescaled profile does not depend on the void size, or - within the range of the simulated catalogue - on the redshift. Comparison of the profiles obtained from simulated and real voids shows an excellent match. The profiles of real voids also show a universal behaviour over a wide range of galaxy luminosities, number densities and redshifts. This points to a fundamental property of the voids found by the watershed algorithm, which can be exploited in future studies of voids.

  18. ?Linear Gas Jet with Tailored Density Profile"

    Energy Technology Data Exchange (ETDEWEB)

    KRISHNAN, Mahadevan

    2012-12-10

    Supersonic, highly collimated gas jets and gas-filled capillary discharge waveguides are two primary targets of choice for Laser Plasma Accelerators (LPA) . Present gas jets have lengths of only 2-4 mm at densities of 1-4E19 cm-3, sufficient for self trapping and electron acceleration to energies up to ~150 MeV. Capillary structures 3 cm long have been used to accelerate beams up to 1 GeV. Capillary discharges used in LPAs serve to guide the pump laser and optimize the energy gain. A wall-stabilized capillary discharge provides a transverse profile across the channel that helps guide the laser and combat diffraction. Gas injection via a fast nozzle at one end provides some longitudinal density control, to improve the coupling. Gas jets with uniform or controlled density profiles may be used to control electron bunch injection and are being integrated into capillary experiments to add tuning of density. The gas jet for electron injection has not yet been optimized. Our Ph-I results have provided the LPA community with an alternative path to realizing a 2-3GeV electron bunch using just a gas jet. For example, our slit/blade combination gives a 15-20mm long acceleration path with tunable density profile, serving as an alternative to a 20-mm long capillary discharge with gas injection at one end. In Ph-II, we will extend these results to longer nozzles, to see whether we can synthesize 30 or 40-mm long plasma channels for LPAs.

  19. Statistical ensembles of virialized halo matter density profiles

    CERN Document Server

    Carron, Julien

    2013-01-01

    We define and study statistical ensembles of matter density profiles describing spherically symmetric, virialized dark matter haloes of finite extent with a given mass and total gravitational potential energy. We provide an exact solution for the grand canonical partition functional, and show its equivalence to that of the microcanonical ensemble. We obtain analytically the mean profiles that correspond to an overwhelming majority of micro-states. All such profiles have an infinitely deep potential well, with the singular isothermal sphere arising in the infinite temperature limit. Systems with virial radius larger than gravitational radius exhibit a localization of a finite fraction of the energy in the very center. The universal logarithmic inner slope of unity of the NFW haloes is predicted at any mass and energy if an upper bound is set to the maximal depth of the potential well. In this case, the statistically favored mean profiles compare well to the NFW profiles. For very massive haloes the agreement b...

  20. Open-cluster density profiles derived using a kernel estimator

    CERN Document Server

    Seleznev, Anton F

    2016-01-01

    Surface and spatial radial density profiles in open clusters are derived using a kernel estimator method. Formulae are obtained for the contribution of every star into the spatial density profile. The evaluation of spatial density profiles is tested against open-cluster models from N-body experiments with N = 500. Surface density profiles are derived for seven open clusters (NGC 1502, 1960, 2287, 2516, 2682, 6819 and 6939) using Two-Micron All-Sky Survey data and for different limiting magnitudes. The selection of an optimal kernel half-width is discussed. It is shown that open-cluster radius estimates hardly depend on the kernel half-width. Hints of stellar mass segregation and structural features indicating cluster non-stationarity in the regular force field are found. A comparison with other investigations shows that the data on open-cluster sizes are often underestimated. The existence of an extended corona around the open cluster NGC 6939 was confirmed. A combined function composed of the King density pr...

  1. Creating steep density profile with a separatrix

    CERN Document Server

    Ogawa, Shun; Vasiliev, Alexei; Garbet, Xavier

    2016-01-01

    The mesoscopic properties of a plasma in a cylindrical magnetic field are investigated from the view point of test-particle dynamics. When the system has enough time and spatial symmetries, a Hamiltonian of a test particle is completely integrable and can be reduced to a single degree of freedom Hamiltonian for each initial state. The reduced Hamiltonian sometimes has an unstable fixed point (saddle point) and a separatrix. Using a maximum entropy principle we compute dynamically compatible equilibrium states of the one particle density function of these systems and discuss how the unstable fixed points affect the density profile or a local pressure gradient, and are able to create a so called internal transport barrier.

  2. Determination of coronal temperatures from electron density profiles

    CERN Document Server

    Lemaire, J F

    2011-01-01

    The most popular method for determining coronal temperatures is the scale-height-method (shm). It is based on electron density profiles inferred from White Light (WL) brightness measurements of the corona during solar eclipses. This method has been applied to several published coronal electron density models. The calculated temperature distributions reach a maximum at r > 1.3 RS, and therefore do not satisfy one of the conditions for applying the shm method. Another method is the hydrostatic equilibrium method (hst), which enables coronal temperature distributions to be determined, providing solutions to the hydrostatic equilibrium equation. The temperature maximas using the hst method are almost equal to those obtained using the shm method, but the temperature peak is always at significantly lower altitude when the hst-method is used than when the shm-method is used. A third and more recently developed method, dyn, can be used for the same published electron density profiles. The temperature distributions ob...

  3. Galactic cannibalism and CDM density profiles

    CERN Document Server

    Nipoti, C; Ciotti, L; Stiavelli, M

    2004-01-01

    Using N-body simulations we show that the process of formation of the brightest cluster galaxy through dissipationless galactic cannibalism can affect the inner cluster dark matter density profile. In particular, we use as realistic test case the dynamical evolution of the galaxy cluster C0337-2522 at redshift z=0.59, hosting in its centre a group of five elliptical galaxies which are likely to be the progenitor of a central giant elliptical. After the formation of the brightest cluster galaxy, the inner cluster dark matter density profile is significantly flatter (logarithmic slope 0.48

  4. On the universality of density profiles

    CERN Document Server

    Del Popolo, A

    2010-01-01

    We use the secondary infall model described in Del Popolo (2009), which takes into account the effect of dynamical friction, ordered and random angular momentum, baryons adiabatic contraction and dark matter baryons interplay, to study how in- ner slopes of relaxed LCDM dark matter (DM) halos with and without baryons (baryons+DM, and pure DM) depend on redshift and on halo mass. We apply the quoted method to structures on galactic scales and clusters of galaxies scales. We find that the inner logarithmic density slope, of dark matter halos with baryons has a significant dependence on halo mass and redshift with slopes ranging from 0 for dwarf galaxies to 0.4 for objects of M = 10^13M_solar and 0.94 for M = 10^15M_solar clusters of galaxies. Structures slopes increase with increasing redshift and this trend reduces going from galaxies to clusters. In the case of density profiles constituted just of dark matter the mass and redshift dependence of slope is very slight. In this last case, we used the Merrit et al...

  5. Proton Stopping Power of Different Density Profile Plasmas

    CERN Document Server

    Casas, David; Andreev, Alexander A; Schnürer, Matthias; Morales, Roberto

    2014-01-01

    In this work, the stopping power of a partially ionized plasma is analyzed by means of free electron stopping and bound electron stopping. For the first one, the RPA dielectric function is used, and for the latter one, an interpolation of high and low projectile velocity formulas is used. The dynamical energy loss of an ion beam inside a plasma is estimated by using an iterative scheme of calculation. The Abel inversion is also applied when we have a plasma with radial symmetry. Finally, we compare our methods with two kind of plasmas. In the first one, we estimate the energy loss in a plasma created by a laser prepulse, whose density is approximated by a piecewise function. For the latter one, a radial electron density is supposed and the stopping is obtained as function of radius from the calculated lateral points. In both cases, the dependence with the density profile is observed.

  6. PROTON STOPPING POWER OF DIFFERENT DENSITY PROFILE PLASMAS

    Directory of Open Access Journals (Sweden)

    David Casas

    2015-04-01

    Full Text Available In this work, the stopping power of a partially ionized plasma is analyzed by means of free electron stopping and bound electron stopping. For the first instance, the RPA dielectric function is used, and for the latter one, an interpolation of high and low projectile velocity formulas is used. The dynamical energy loss of a ion beam inside a plasma is estimated by using an iterative scheme of calculation. The Abel inversion is also applied when we have a plasma with radial symmetry. Finally, we compare our methods with two kind of plasmas. In the first one, we estimate the energy loss in a plasma created by a laser prepulse, whose density is approximated by a piecewise function. For the latter one, a radial electron density is supposed and the stopping is obtained as a function of radius from the calculated lateral points. In both cases, the dependence with the density profile is observed.

  7. Coronal temperature profiles obtained from kinetic models and from coronal brightness measurements obtained during solar eclipses

    CERN Document Server

    Pierrard, V; Lemaire, J F

    2012-01-01

    Coronal density, temperature and heat flux distributions for the equatorial and polar corona have been deduced by Lemaire [2012] from Saito's model of averaged coronal white light (WL) brightness and polarization observations. They are compared with those determined from a kinetic collisionless/exospheric model of the solar corona. This comparison indicates rather similar distributions at large radial distances (> 7 Rs) in the collisionless region. However, rather important differences are found close to the Sun in the acceleration region of the solar wind. The exospheric heat flux is directed away from the Sun, while that inferred from all WL coronal observations is in the opposite direction, i.e., conducting heat from the inner corona toward the chromosphere. This could indicate that the source of coronal heating rate extends up into the inner corona where it maximizes at r > 1.5 Rs well above the transition region.

  8. A laser-induced fluorescence measurement technique for obtaining neutral hydrogen densities in plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Yao, X.Z.; Yang, T.F.; Chang-Diaz, F.R. [Plasma Fusion Center, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139 (United States)

    1995-09-01

    The resonance fluorescence of neutral hydrogen illuminated by {ital H}{sub {alpha}} radiation has been used as a technique for the spatially and temporally resolved density measurements of neutral hydrogen in high temperature plasmas, such as in the tokamak and magnetic mirror plasma fusion devices. The fluorescence signal, usually very weak and buried in the background of stray laser light and {ital H}{sub {alpha}} emission, is very difficult to extract and its measurements are inaccurate. This paper discusses the improvement of the signal extraction using two optical path laser-induced fluorescence (LIF) methods. One optical path carries the fluorescence signal and the background (the stray laser light and {ital H}{sub {alpha}} emission), whereas the other path carries only the background signal. By combining these two signals, a clean fluorescence signal can be isolated by subtracting out the background using a differential amplifier. The measurement is obtained instantaneously from these two signals which are taken simultaneously in one pulse rather than being extracted from two separate spectra taken in two sequential pulses (double pulses). This method, therefore, makes a significant improvement on the double pulse technique in terms of the accuracy of the measurement and the time resolution. Using this LIF technique the measurement of the neutral density profile in the exhaust of a tandem mirror plasma propulsion device is obtained and presented. {copyright} {ital 1995} {ital American} {ital Institute} {ital of} {ital Physics}.

  9. Scaling Evolution of Universal Dark-Matter Halo Density Profiles

    CERN Document Server

    Raig, A; Salvador-Solé, E

    1998-01-01

    Dark-matter halos show a universal density profile with a scaling such that less massive systems are typically denser. This mass-density relation is well described by a proportionality between the characteristic density of halos and the mean cosmic density at halo formation time. It has recently been shown that this proportionality could be the result of the following simple evolutionary picture. Halos form in major mergers with essentially the same, cosmogony-dependent, dimensionless profile, and then grow inside-outside, as a consequence of accretion. Here we verify the consistency of this picture and show that it predicts the correct zero point of the mass-density relation.

  10. Optimally focused cold atom systems obtained using density-density correlations.

    Science.gov (United States)

    Putra, Andika; Campbell, Daniel L; Price, Ryan M; De, Subhadeep; Spielman, I B

    2014-01-01

    Resonant absorption imaging is a common technique for detecting the two-dimensional column density of ultracold atom systems. In many cases, the system's thickness along the imaging direction greatly exceeds the imaging system's depth of field, making the identification of the optimally focused configuration difficult. Here we describe a systematic technique for bringing Bose-Einstein condensates (BEC) and other cold-atom systems into an optimal focus even when the ratio of the thickness to the depth of field is large: a factor of 8 in this demonstration with a BEC. This technique relies on defocus-induced artifacts in the Fourier-transformed density-density correlation function (the power spectral density, PSD). The spatial frequency at which these artifacts first appear in the PSD is maximized on focus; the focusing process therefore both identifies and maximizes the range of spatial frequencies over which the PSD is uncontaminated by finite-thickness effects.

  11. Avalanche consumption and the stationary regions of the density profile around the droplets in the theory of condensation

    OpenAIRE

    Kurasov, V.

    1998-01-01

    The contradiction between the stationary aproach to the density profile and the avalanche character of the metastable phase consumption is investigated. The exact solution for the metastable phase profile is obtained. The reconsidered value for the special parameter responsible for the hierarchy in the structure of the density profile around the droplet is presented.

  12. Void alignment and density profile applied to measuring cosmological parameters

    CERN Document Server

    Dai, De-Chang

    2015-01-01

    We study the orientation and density profiles of the cosmological voids with SDSS10 data. Using voids to test Alcock-Paczynski effect has been proposed and tested in both simulations and actual SDSS data. Previous observations imply that there exist an empirical stretching factor which plays an important role in the voids' orientation. Simulations indicate that this empirical stretching factor is caused by the void galaxies' peculiar velocities. Recently Hamaus et al. found that voids' density profiles are universal and their average velocities satisfy linear theory very well. In this article we first confirm that the stretching effect exists using independent analysis. We then apply the universal density profile to measure the cosmological parameters. We find that the void density profile can be a tool to measure the cosmological parameters.

  13. Electron Density Profile Data Contains Virtual Height/Frequency Pairs from a Profile or Profiles (Composite Months) of Ionograms

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Electron Density Profile, N(h), data set contains both individual profiles and composite months. The data consist of virtual height/frequency pairs from a...

  14. Calculating electron momentum densities and Compton profiles using the linear tetrahedron method.

    Science.gov (United States)

    Ernsting, D; Billington, D; Haynes, T D; Millichamp, T E; Taylor, J W; Duffy, J A; Giblin, S R; Dewhurst, J K; Dugdale, S B

    2014-12-10

    A method for computing electron momentum densities and Compton profiles from ab initio calculations is presented. Reciprocal space is divided into optimally-shaped tetrahedra for interpolation, and the linear tetrahedron method is used to obtain the momentum density and its projections such as Compton profiles. Results are presented and evaluated against experimental data for Be, Cu, Ni, Fe3Pt, and YBa2Cu4O8, demonstrating the accuracy of our method in a wide variety of crystal structures.

  15. Characterization of Density Profile of Cylindrical Pulsed Gas Jets

    Institute of Scientific and Technical Information of China (English)

    YU Quan-Zhi; LI Yu-Tong; ZhANG Jie; ZHENG Jun; LI Han-Ming; PENG Xiao-Yu; LI Kun

    2004-01-01

    @@ We investigated the characteristics of argon and helium gas jets produced by a cylindrical nozzle under pressures from I to 6 Mpa using a femtosecond laser interferometry. A radial parabolic distribution and an axial exponential distribution of the gas jet density profiles are identified. The results show that the density increases linearly with the backing pressure.

  16. A representative density profile of the North Greenland snowpack

    Science.gov (United States)

    Florian Schaller, Christoph; Freitag, Johannes; Kipfstuhl, Sepp; Laepple, Thomas; Steen-Larsen, Hans Christian; Eisen, Olaf

    2016-09-01

    Along a traverse through North Greenland in May 2015 we collected snow cores up to 2 m depth and analyzed their density and water isotopic composition. A new sampling technique and an adapted algorithm for comparing data sets from different sites and aligning stratigraphic features are presented. We find good agreement of the density layering in the snowpack over hundreds of kilometers, which allows the construction of a representative density profile. The results are supported by an empirical statistical density model, which is used to generate sets of random profiles and validate the applied methods. Furthermore we are able to calculate annual accumulation rates, align melt layers and observe isotopic temperatures in the area back to 2010. Distinct relations of δ18O with both accumulation rate and density are deduced. Inter alia the depths of the 2012 melt layers and high-resolution densities are provided for applications in remote sensing.

  17. Advances in the density profile evaluation from broadband reflectometry on ASDEX upgrade

    Energy Technology Data Exchange (ETDEWEB)

    Varela, P.; Manso, M. [Associacao EURATOM/IST, Centro de Fusao Nuclear, Instituto Superior Tecnico, Lisboa (Portugal); Conway, G. [Max-Planck-Instituet fuer Plasmaphysik, EURATOM Association, Garching (Germany)

    2001-05-01

    The high temporal and spatial resolutions provided by broadband microwave reflectometry make it an attractive diagnostic technique to measure the density profile in fusion plasmas. However, great problems have been encountered due to the plasma turbulence that difficult, and sometimes prevent, the routine evaluation of density profiles. Advanced broadband systems employ ultra-fast sweeping in an attempt to perform the profile measurement in a time window smaller than the temporal scale of the main plasma fluctuations but this is not sufficient. Indeed, abrupt plasma movements and/or spatial turbulence always affect the reflectometry signals, as shown by numerical studies (with both one- and two-dimensional codes), for the case of ultra-fast sweeping and pulse radar systems. For this reason not only the system performance is important but the software tools also play a crucial role for reflectometry to become a standard density profile diagnostic. Here we present the recent advances towards automatic evaluation of density profiles from broadband reflectometry on ASDEX Upgrade. For regimes with moderate levels of plasma turbulence, density profiles are obtained from single reflectometry samples (temporal resolution of 20 {mu}s), and for higher turbulence levels average profiles are obtained from bursts of ultra-fast (20 {mu}s), closely spaced (10 {mu}s) sweeps. This method improved the accuracy and reliability of density profiles, which can now be obtained automatically from the edge to the bulk plasma - using reflectometry alone - in most plasma regimes of ASDEX Upgrade. New data processing capability has been implemented that allows the profiles to be available to the end-users 10-12 minutes after each discharge. These developments were possible due to the flexibility and high performance of the control and data acquisition systems and to the large number of measurements that can be performed with the diagnostic during each discharge (720 profiles both on the low

  18. Measurements of electron density profiles using an angular filter refractometer

    Energy Technology Data Exchange (ETDEWEB)

    Haberberger, D., E-mail: dhab@lle.rochester.edu; Ivancic, S.; Hu, S. X.; Boni, R.; Barczys, M.; Craxton, R. S.; Froula, D. H. [Laboratory for Laser Energetics, University of Rochester, Rochester, New York 14636 (United States)

    2014-05-15

    A novel diagnostic technique, angular filter refractometry (AFR), has been developed to characterize high-density, long-scale-length plasmas relevant to high-energy-density physics experiments. AFR measures plasma densities up to 10{sup 21} cm{sup −3} with a 263-nm probe laser and is used to study the plasma expansion from CH foil and spherical targets that are irradiated with ∼9 kJ of ultraviolet (351-nm) laser energy in a 2-ns pulse. The data elucidate the temporal evolution of the plasma profile for the CH planar targets and the dependence of the plasma profile on target radius for CH spheres.

  19. Hydrogen concentration and mass density of diamondlike carbon films obtained by x-ray and neutron reflectivity

    DEFF Research Database (Denmark)

    Findeisen, E.; Feidenhans'l, R.; Vigild, Martin Etchells

    1994-01-01

    Specular reflectivity of neutrons and x rays can be used to determine the scattering length density profile of a material perpendicular to its surface. We have applied these techniques to study amorphous, diamondlike, hydrocarbon films. By the combination of these two techniques we obtain not only...... the mass density, but also the concentration of hydrogen, which varies in our case between 0 and 30 at.%. This method is a new and nondestructive way to determine the concentration of hydrogen within an error of less than 2 at.% in samples with sharp interfaces. It is especially suited for diamondlike...... carbon films....

  20. Why are Halo Density Profiles Stable at Formation?

    CERN Document Server

    González-Casado, G; Salvador-Solé, E

    1998-01-01

    We analyze the physical justification of the picture proposed by Salvador-Sole et al. in these proceedings for the time evolution of the universal density profile of dark-matter halos. According to this picture, halos have at formation a stable (i.e. independent of mass and time) dimensionless density profile, the characteristic length and density scales of the profile depending on the underlying cosmogony. Subsequent evolution is driven by mass accretion onto the outskirts of halos and can be characterized simply by the increment of halo radius with time and the corresponding decrease of the critical density of the universe. We find this picture to be a reasonable good description of the expected evolution of halos in hierarchical models of structure formation.

  1. Application of resistograph to obtain the density and to differentiate wood species

    Directory of Open Access Journals (Sweden)

    Acuña, Luis

    2011-09-01

    Full Text Available This project offers a methodology for the analysis of resistographic profiles obtained from samples of wood and the extraction of precise data from these profiles. Tests were conducted on healthy samples of wood from six different species, as well as on “old” wood in use as part of timber structures with an age of 80-120 years. Based on the data collected using the resistograph, a series of variables was determined, and statistically analysed. An analysis of the data reveals the close relation between the resistographic variables and wood density (R2> 90%. Equally, in the case of healthy wood, an analysis of the defined variables permits the identification of the species of the sample with a very high probability and, therefore, its indirect resistance values.

    En este trabajo se aporta una metodología para realizar el análisis de los perfiles resistográficos obtenidos de piezas de madera y poder con ello obtener con precisión determinados datos de las mismas. Los ensayos se realizaron sobre madera sana de seis especies distintas, así como sobre piezas de madera “antigua” en uso, pertenecientes a estructuras de edificaciones con unos 80-120 años de servicio. A partir de los datos recogidos por el resistógrafo se definieron una serie de variables, y fueron analizadas estadísticamente. Del análisis de los datos cabe destacar la magnífica relación existente entre las variables resistográficas y la densidad de la madera (R2> 90%. Igualmente, en el caso de madera sana, el análisis de las variables definidas permite asignar con una probabilidad muy elevada, la especie a la que pueda pertenecer y, por consiguiente, sus valores resistentes indirectos.

  2. Simulating confined particles with a flat density profile

    Science.gov (United States)

    Korolkovas, Airidas

    2016-08-01

    Particle simulations confined by sharp walls usually develop an oscillatory density profile. For some applications, most notably soft matter liquids, this behavior is often unrealistic and one expects a monotonic density climb instead. To reconcile simulations with experiments, we propose mirror-and-shift boundary conditions where each interface is mapped to a distant part of itself. The main result is that the particle density increases almost monotonically from zero to bulk, over a short distance of about one particle diameter. The method is applied to simulate a polymer brush in explicit solvent, grafted on a flat silicon substrate. The simulated density profile agrees favorably with neutron reflectometry measurements and self-consistent field theory results.

  3. Simulating confined particles with a flat density profile

    CERN Document Server

    Korolkovas, Airidas

    2016-01-01

    Particle simulations confined by sharp walls usually develop an oscillatory density profile. For some applications, most notably soft matter liquids, this behavior is often unrealistic and one expects a monotonic density climb instead. To reconcile simulations with experiments, we propose mirror-and-shift boundary conditions where each interface is mapped to a distant part of itself. The main result is that the particle density increases almost monotonically from zero to bulk, over a short distance of about one particle diameter. The method is applied to simulate a polymer brush in explicit solvent, grafted on a flat silicon substrate. The simulated density profile agrees favorably with neutron reflectometry measurements and self-consistent field theory results.

  4. Fitting of the Thomson scattering density and temperature profiles on the COMPASS tokamak

    Science.gov (United States)

    Stefanikova, E.; Peterka, M.; Bohm, P.; Bilkova, P.; Aftanas, M.; Sos, M.; Urban, J.; Hron, M.; Panek, R.

    2016-11-01

    A new technique for fitting the full radial profiles of electron density and temperature obtained by the Thomson scattering diagnostic in H-mode discharges on the COMPASS tokamak is described. The technique combines the conventionally used modified hyperbolic tangent function for the edge transport barrier (pedestal) fitting and a modification of a Gaussian function for fitting the core plasma. Low number of parameters of this combined function and their straightforward interpretability and controllability provide a robust method for obtaining physically reasonable profile fits. Deconvolution with the diagnostic instrument function is applied on the profile fit, taking into account the dependence on the actual magnetic configuration.

  5. Flat Central Density Profile and Constant DM Surface Density in Galaxies from Scalar Field Dark Matter

    CERN Document Server

    Robles, Victor H

    2012-01-01

    The scalar field dark matter (SFDM) model proposes that galaxies form by condensation of a scalar field (SF) very early in the universe forming Bose-Einstein Condensates (BEC) drops, i.e., in this model haloes of galaxies are gigantic drops of SF. Here big structures form like in the LCDM model, by hierarchy, thus all the predictions of the LCDM model at big scales are reproduced by SFDM. This model predicts that all galaxies must be very similar and exist for bigger redshifts than in the LCDM model. In this work we show that BEC dark matter haloes fit high-resolution rotation curves of a sample of thirteen low surface brightness galaxies. We compare our fits to those obtained using a Navarro-Frenk-White and Pseudo-Isothermal (PI) profiles and found a better agreement with the SFDM and PI profiles. The mean value of the logarithmic inner density slopes is -0.27 +/- 0.18. As a second result we find a natural way to define the core radius with the advantage of being model-independent. Using this new definition ...

  6. High current density ion beam obtained by a transition to a highly focused state in extremely low-energy region.

    Science.gov (United States)

    Hirano, Y; Kiyama, S; Fujiwara, Y; Koguchi, H; Sakakita, H

    2015-11-01

    A high current density (≈3 mA/cm(2)) hydrogen ion beam source operating in an extremely low-energy region (E(ib) ≈ 150-200 eV) has been realized by using a transition to a highly focused state, where the beam is extracted from the ion source chamber through three concave electrodes with nominal focal lengths of ≈350 mm. The transition occurs when the beam energy exceeds a threshold value between 145 and 170 eV. Low-level hysteresis is observed in the transition when E(ib) is being reduced. The radial profiles of the ion beam current density and the low temperature ion current density can be obtained separately using a Faraday cup with a grid in front. The measured profiles confirm that more than a half of the extracted beam ions reaches the target plate with a good focusing profile with a full width at half maximum of ≈3 cm. Estimation of the particle balances in beam ions, the slow ions, and the electrons indicates the possibility that the secondary electron emission from the target plate and electron impact ionization of hydrogen may play roles as particle sources in this extremely low-energy beam after the compensation of beam ion space charge.

  7. New signal processing technique for density profile reconstruction using reflectometry

    Energy Technology Data Exchange (ETDEWEB)

    Clairet, F.; Bottereau, C. [CEA, IRFM, F-13108 Saint-Paul-lez-Durance (France); Ricaud, B. [CEA, IRFM, F-13108 Saint-Paul-lez-Durance (France); CPT UMR 6207, Campus de Luminy, case 907, F-13288 Marseille (France); Briolle, F. [CPT UMR 6207, Campus de Luminy, case 907, F-13288 Marseille (France); CReA, BA 701, F-13306 Salon de Provence (France); Heuraux, S. [IJL-P2M, UMR-CNRS 7198, Universite Henri Poincare, F-54506 Vandoeuvre (France)

    2011-08-15

    Reflectometry profile measurement requires an accurate determination of the plasma reflected signal. Along with a good resolution and a high signal to noise ratio of the phase measurement, adequate data analysis is required. A new data processing based on time-frequency tomographic representation is used. It provides a clearer separation between multiple components and improves isolation of the relevant signals. In this paper, this data processing technique is applied to two sets of signals coming from two different reflectometer devices used on the Tore Supra tokamak. For the standard density profile reflectometry, it improves the initialization process and its reliability, providing a more accurate profile determination in the far scrape-off layer with density measurements as low as 10{sup 16} m{sup -1}. For a second reflectometer, which provides measurements in front of a lower hybrid launcher, this method improves the separation of the relevant plasma signal from multi-reflection processes due to the proximity of the plasma.

  8. Profiling compact toroid plasma density on CTIX with laser deflection

    Science.gov (United States)

    Brockington, Samuel Joseph Erwin

    A laser deflectometer measures line-integrated plasma density gradient using laser diodes and amplified point detectors. A laser passing through an optically thin plasma is refracted by an amount proportional to the line-integrated electron density gradient. I have designed, installed, and operated a deflection diagnostic for the Compact Toroid Injection Experiment (CTIX), a plasma rail gun which can create compact toroid (CT) plasmas of controllable density and velocity. The diagnostic design and motivation are discussed, as well as three experiments performed with deflectometry. Thus, my thesis consists of the design of the deflectometer diagnostic, a comparison of its accuracy to interferometer density measurements, and finally a survey of compact toroid density profiles in two dimensions conducted with an array of detectors.

  9. Is it possible to obtain cosmic accelerated expansion through energy transfer between different energy densities?

    Science.gov (United States)

    Erdem, Recai

    2017-03-01

    The equation of state of an energy density may be significantly modified by coupling it to another energy density. In the light of this observation we check the possibility of producing cosmic accelerated expansion in this way. In particular we consider the case where matter is converted to radiation (or vice versa by particle physics processes). We find that cosmic accelerated expansion can be obtained in this way only if an intermediate state with negative equation of state forms during the conversion.

  10. Ionospheric topside models compared with experimental electron density profiles

    Directory of Open Access Journals (Sweden)

    S. M. Radicella

    2005-06-01

    Full Text Available Recently an increasing number of topside electron density profiles has been made available to the scientific community on the Internet. These data are important for ionospheric modeling purposes, since the experimental information on the electron density above the ionosphere maximum of ionization is very scarce. The present work compares NeQuick and IRI models with the topside electron density profiles available in the databases of the ISIS2, IK19 and Cosmos 1809 satellites. Experimental electron content from the F2 peak up to satellite height and electron densities at fixed heights above the peak have been compared under a wide range of different conditions. The analysis performed points out the behavior of the models and the improvements needed to be assessed to have a better reproduction of the experimental results. NeQuick topside is a modified Epstein layer, with thickness parameter determined by an empirical relation. It appears that its performance is strongly affected by this parameter, indicating the need for improvements of its formulation. IRI topside is based on Booker's approach to consider two parts with constant height gradients. It appears that this formulation leads to an overestimation of the electron density in the upper part of the profiles, and overestimation of TEC.

  11. On the physical origin of dark matter density profiles

    CERN Document Server

    Ascasibar, Y; Gottlöber, S; Müller, V

    2003-01-01

    The radial mass distribution of dark matter haloes is investigated within the framework of the spherical infall model. We present a new formulation of spherical collapse including non-radial motions, and compare the analytical profiles with a set of high-resolution N-body simulations ranging from galactic to cluster scales. We argue that the dark matter density profile is entirely determined by the initial conditions, which are described by only two parameters: the height of the primordial peak and the smoothing scale. These are physically meaningful quantities in our model, related to the mass and formation time of the halo. Angular momentum is dominated by velocity dispersion, and it is responsible for the shape of the density profile near the centre. The phase-space density of our simulated haloes is well described by a power-law profile, rho/sigma^3 = 10^{1.46\\pm0.04} (rho_c/Vvir^3) (r/Rvir)^{-1.90\\pm0.05}. Setting the eccentricity of particle orbits according to the numerical results, our model is able t...

  12. Advanced Tokamak current density profiles for non-inductive Tore Supra operation

    Energy Technology Data Exchange (ETDEWEB)

    Kazarian-Vibert, F.; Litaudon, X.; Arslanbekov, R.; Bibet, P.; Froissard, P.; Goniche, M.; Hoang, G.T.; Joffrin, E.; Moreau, D.; Peysson, Y.; Rey, G. [Association Euratom-CEA, Centre d`Etudes de Cadarache, 13 - Saint-Paul-lez-Durance (France). Dept. de Recherches sur la Fusion Controlee

    1995-12-31

    This document deals with the advanced Tokamak concept concerning self consistent hollow current density profiles. Several Lower Hybrid experiments performed on Tore Supra are presented: the feasibility of the constant-flux operation mode is demonstrated and a new improved confinement regime with a reversed shear has been obtained. (TEC). 12 refs., 5 figs.

  13. Midplane neutral density profiles in the National Spherical Torus Experiment

    Energy Technology Data Exchange (ETDEWEB)

    Stotler, D. P., E-mail: dstotler@pppl.gov; Bell, R. E.; Diallo, A.; LeBlanc, B. P.; Podestà, M.; Roquemore, A. L.; Ross, P. W. [Princeton Plasma Physics Laboratory, Princeton University, P. O. Box 451, Princeton, New Jersey 08543-0451 (United States); Scotti, F. [Lawrence Livermore National Laboratory, Livermore, California 94551 (United States)

    2015-08-15

    Atomic and molecular density data in the outer midplane of NSTX [Ono et al., Nucl. Fusion 40, 557 (2000)] are inferred from tangential camera data via a forward modeling procedure using the DEGAS 2 Monte Carlo neutral transport code. The observed Balmer-β light emission data from 17 shots during the 2010 NSTX campaign display no obvious trends with discharge parameters such as the divertor Balmer-α emission level or edge deuterium ion density. Simulations of 12 time slices in 7 of these discharges produce molecular densities near the vacuum vessel wall of 2–8 × 10{sup 17 }m{sup −3} and atomic densities ranging from 1 to 7 × 10{sup 16 }m{sup −3}; neither has a clear correlation with other parameters. Validation of the technique, begun in an earlier publication, is continued with an assessment of the sensitivity of the simulated camera image and neutral densities to uncertainties in the data input to the model. The simulated camera image is sensitive to the plasma profiles and virtually nothing else. The neutral densities at the vessel wall depend most strongly on the spatial distribution of the source; simulations with a localized neutral source yield densities within a factor of two of the baseline, uniform source, case. The uncertainties in the neutral densities associated with other model inputs and assumptions are ≤50%.

  14. Density profiles of dark matter halos with anisotropic velocity tensors

    CERN Document Server

    Hiotelis, N

    2002-01-01

    We present density profiles, that are solutions of the spherical Jeans equation, derived under the following two assumptions: (i) the coarse grained phase-density follows a power-law of radius, rho/(sigma^3) proportional to r^{-alpha}, and (ii) the velocity anisotropy parameter is given by the relation beta_a(r) = beta_1 + 2 beta_2 {(r/r_*)/(1+(r/r_*)^2)} where beta_1, beta_2 are parameters and r_* equals twice the virial radius, r_{vir}, of the system. These assumptions are well motivated by the results of N-body simulations. Density profiles have increasing logarithmic slopes gamma, defined by gamma = - {(d ln rho)/(d ln r)}. The values of gamma at r = 10^{-2.5}r_{vir}, a distance where the systems could be resolved by large N-body simulations, lie in the range 1. - 1.6. These inner values of gamma increase for increasing beta_1 and for increasing concentration of the system. On the other hand, slopes at r = r_{vir} lie in the range 2.42 - 3.82. A model density profile that fits well the results at radial d...

  15. Density and impurity profile behaviours in HL-2A tokamak with different gas fuelling methods

    Institute of Scientific and Technical Information of China (English)

    Cui Zheng-Ying; Zhou Yan; Li Wei; Feng Bei-Bin; Sun Ping; Dong Chun-Feng; Liu Yi; Hong Wen-Yu; Yang Qing-Wei; Ding Xuan-Tong; Duan Xu-Ru

    2009-01-01

    The electron density profile peaking and the impurity accumulation in the HL-2A tokamak plasma are observed when three kinds of fuelling methods are separately used at different fuelling particle locations.The density profile becomes more peaked when the line-averaged electron density approaches the Greenwald density limit nG and,consequently,impurity accumulation is often observed.A linear increase regime in the density range ne<0.6nG and a saturation regime in ne>0.6nG are obtained.There is no significant difference in achieved density peaking factor fne between the supersonic molecular beam injection (SMBI) and gas puffing into the plasma main chamber.However,the achieved fne is relatively low,in particular,in the case of density below 0.7nG,when the working gas is puffed into the divertor chamber.A discharge with a density as high as 1.2nG,i.e.ne=1.2nG,can be achieved by SMBI just after siliconization as a wall conditioning.The metallic impurities,such as iron and chromium,also increase remarkably when the impurity accumulation happens.The mechanism behind the density peaking and impurity accumulation is studied by investigating both the density peaking factor versus the effective collisionality and the radiation peaking versus density peaking.

  16. Mass, velocity anisotropy and pseudo phase space density profiles of Abell 2142

    CERN Document Server

    Munari, Emiliano; Mamon, Gary

    2013-01-01

    Aim: We aim to compute the mass and velocity anisotropy profiles of Abell 2142 and, from there, the pseudo phase space density profile $Q(r)$ and the density slope - velocity anisotropy $\\beta - \\gamma$ relation, and compare them with theoretical expectations. Methods: The mass profiles have been obtained by using three techniques based on member galaxy kinematics, namely the caustic method, the method of Dispersion - Kurtosis and MAMPOSSt. Through the inversion of the Jeans equation it has been possible to compute the velocity anisotropy profiles. Results: The mass profiles, as well as the virial values of mass and radius, computed with the different techniques are in agreement with one another and with the estimates coming from X-ray and weak lensing studies. A concordance mass profile is obtained by averaging the lensing, X-ray and kinematics determinations. The cluster mass profile is well fit by an NFW profile with $c=4.0 \\pm 0.5$. The population of red and blue galaxies appear to have a different veloci...

  17. Reconstruction of edge density profiles on Large Helical Device using ultrashort-pulse reflectometry.

    Science.gov (United States)

    Yokota, Yuya; Mase, Atsushi; Kogi, Yuichiro; Tokuzawa, Tokihiko; Kawahata, Kazuo; Nagayama, Yoshio; Hojo, Hitoshi

    2008-10-01

    Reflectometry has been expected to be one of the key diagnostics to measure density profiles. We have applied an ultrashort-pulse reflectometry (USPR) system to Large Helical Device in the National Institute for Fusion Science. Wide frequency band system is required to obtain wide density profile since an incident wave is reflected at the density layer corresponding to its cutoff frequency. The reflectometry utilizes an impulse with less than 30 ps pulse width as a source. Since the bandwidth of an impulse has an inverse relation to the pulse width, we can cover the frequency range of micro- to millimeter waves (18-40 GHz) with a single source. The density profiles can be reconstructed by collecting time-of-flight (TOF) signals for each frequency component of an impulse reflected from the corresponding cutoff layer. We utilize the signal record analysis (SRA) method to reconstruct the density profiles from the TOF signal. The effectiveness of the SRA method for the profile reconstruction is confirmed by a simulation study of the USPR using a finite-difference time domain method.

  18. Statistics of cosmic density profiles from perturbation theory

    CERN Document Server

    Bernardeau, Francis; Codis, Sandrine

    2013-01-01

    The joint probability distribution function (PDF) of the density within multiple concentric spherical cells is considered. It is shown how its cumulant generating function can be obtained at tree order in perturbation theory as the Legendre transform of a function directly built in terms of the initial moments. In the context of the upcoming generation of large-scale structure surveys, it is conjectured that this result correctly models such a function for finite values of the variance. Detailed consequences of this assumption are explored. In particular the corresponding one-cell density probability distribution at finite variance is computed for realistic power spectra, taking into account its scale variation. It is found to be in agreement with $\\Lambda$-CDM simulations at the few percent level for a wide range of density values and parameters. Related explicit analytic expansions at the low and high density tails are given. The conditional (at fixed density) and marginal probability of the slope -- the de...

  19. Computational lipidology: predicting lipoprotein density profiles in human blood plasma.

    Directory of Open Access Journals (Sweden)

    Katrin Hübner

    2008-05-01

    Full Text Available Monitoring cholesterol levels is strongly recommended to identify patients at risk for myocardial infarction. However, clinical markers beyond "bad" and "good" cholesterol are needed to precisely predict individual lipid disorders. Our work contributes to this aim by bringing together experiment and theory. We developed a novel computer-based model of the human plasma lipoprotein metabolism in order to simulate the blood lipid levels in high resolution. Instead of focusing on a few conventionally used predefined lipoprotein density classes (LDL, HDL, we consider the entire protein and lipid composition spectrum of individual lipoprotein complexes. Subsequently, their distribution over density (which equals the lipoprotein profile is calculated. As our main results, we (i successfully reproduced clinically measured lipoprotein profiles of healthy subjects; (ii assigned lipoproteins to narrow density classes, named high-resolution density sub-fractions (hrDS, revealing heterogeneous lipoprotein distributions within the major lipoprotein classes; and (iii present model-based predictions of changes in the lipoprotein distribution elicited by disorders in underlying molecular processes. In its present state, the model offers a platform for many future applications aimed at understanding the reasons for inter-individual variability, identifying new sub-fractions of potential clinical relevance and a patient-oriented diagnosis of the potential molecular causes for individual dyslipidemia.

  20. LPWA using supersonic gas jet with tailored density profile

    Science.gov (United States)

    Kononenko, O.; Bohlen, S.; Dale, J.; D'Arcy, R.; Dinter, M.; Erbe, J. H.; Indorf, G.; di Lucchio, L.; Goldberg, L.; Gruse, J. N.; Karstensen, S.; Libov, V.; Ludwig, K.; Martinez de La Ossa, A.; Marutzky, F.; Niroula, A.; Osterhoff, J.; Quast, M.; Schaper, L.; Schwinkendorf, J.-P.; Streeter, M.; Tauscher, G.; Weichert, S.; Palmer, C.; Horbatiuk, Taras

    2016-10-01

    Laser driven plasma wakefield accelerators have been explored as a potential compact, reproducible source of relativistic electron bunches, utilising an electric field of many GV/m. Control over injection of electrons into the wakefield is of crucial importance in producing stable, mono-energetic electron bunches. Density tailoring of the target, to control the acceleration process, can also be used to improve the quality of the bunch. By using gas jets to provide tailored targets it is possible to provide good access for plasma diagnostics while also producing sharp density gradients for density down-ramp injection. OpenFOAM hydrodynamic simulations were used to investigate the possibility of producing tailored density targets in a supersonic gas jet. Particle-in-cell simulations of the resulting density profiles modelled the effect of the tailored density on the properties of the accelerated electron bunch. Here, we present the simulation results together with preliminary experimental measurements of electron and x-ray properties from LPWA experiments using gas jet targets and a 25 TW, 25 fs Ti:Sa laser system at DESY.

  1. Comparison of density cutters for snow profile observations

    Science.gov (United States)

    Conger, Steven M.; McClung, David M.

    An investigation was made to estimate the variance, measurement errors and sampling error in currently accepted practices for manual snow density measurement carried out as part of snow profile observations using the available variety of density cutters. A field experiment in dry snow conditions was conducted using a randomized block design to account for layer spatial variability. Cutter types included a 500 cm3 aluminium tube, 200 and 100 cm3 stainless-steel box types, 200 cm3 stainless-steel wedge types and a 100 cm3 stainless-steel tube. Without accounting for variation due to weighing devices, the range of values for 'accepted practice' determined in this study included variation within individual cutters of 0.8-6.2%, variation between cutters of 3-12%, variation between cutter means and layer means of 2-7%, and under-sampling errors of 0-2%. The results of a statistical analysis suggest that snow density measurements taken using various density cutters are significantly different from each other. Without adjustment for under-sampling, and given that the mean of all measurements is the accepted true value of the layer density, variation exclusively between cutter types provides 'accepted practice' measurements that are within 11% of the true density.

  2. X-ray structure refinement using aspherical atomic density functions obtained from quantum-mechanical calculations.

    Science.gov (United States)

    Jayatilaka, Dylan; Dittrich, Birger

    2008-05-01

    An approach is outlined for X-ray structure refinement using atomic density fragments obtained by Hirshfeld partitioning of quantum-mechanical density fragments. Results are presented for crystal structure refinements of urea and benzene using these 'Hirshfeld atoms'. Using this procedure, the quantum-mechanical non-spherical electron density is taken into account in the structural model based on the conformation found in the crystal. Contrary to current consensus in structure refinement, the anisotropic displacement parameters of H atoms can be reproduced from neutron diffraction measurements simply from a least-squares fit using the Hirshfeld atoms derived from the BLYP level of theory and including a simple point-charge model to treat the crystal environment.

  3. Effect of electrolysis parameters on the morphologies of copper powder obtained at high current densities

    Directory of Open Access Journals (Sweden)

    Orhan Gökhan

    2012-01-01

    Full Text Available The effects of copper ion concentrations and electrolyte temperature on the morphologies and on the apparent densities of electrolytic copper powders at high current densities under galvanostatic regime were examined. These parameters were evaluated by the current efficiency of hydrogen evolution. In addition, scanning electron microscopy was used for analyzing the morphology of the copper powders. It was found that the morphology was dependent over the copper ion concentration and electrolyte temperature under same current density (CD conditions. At 150 mA cm-2 and the potential of 1000±20 mV (vs. SCE, porous and disperse copper powders were obtained at low concentrations of Cu ions (0.120 M Cu2+ in 0.50 M H2SO4. Under this condition, high rate of hydrogen evolution reaction took place parallel to copper electrodeposition. The morphology was changed from porous, disperse and cauliflower-like to coral-like, shrub-like and stalk-stock like morphology with the increasing of Cu ion concentrations towards 0.120 M, 0.155 M, 0.315 M, 0.475 M and 0.630 M Cu2+ in 0.5 M H2SO4 respectively at the same CD. Similarly, as the temperature was increased, powder morphology and apparent density were observed to be changed. The apparent density values of copper powders were found to be suitable for many of the powder metallurgy applications.

  4. Extreme-infrared brightness profile of the solar chromosphere obtained during the total eclipse of 1991

    Science.gov (United States)

    Lindsey, C.; Jefferies, J. T.; Clark, T. A.; Harrison, R. A.; Carter, M. K.; Watt, G.; Becklin, E. E.; Roellig, T. L.; Braun, D. C.; Naylor, D. A.

    1992-01-01

    A temperature profile in 1.3 mm radiation with about 300 km resolution at the sun was obtained during the total eclipse of 1991. The observations indicate that spicules reach a temperature of 8000 K at 3000-4000 km above the photosphere. This temperature is lower than those of many spicule models.

  5. Isotope and density profile effects on pedestal neoclassical transport

    Science.gov (United States)

    Buller, S.; Pusztai, I.

    2017-10-01

    Cross-field neoclassical transport of heat, particles and momentum is studied in sharp density pedestals, with a focus on isotope and profile effects, using a radially global approach. Global effects—which tend to reduce the peak ion heat flux, and shift it outward—increase with isotope mass for fixed profiles. The heat flux reduction exhibits a saturation with a favorable isotopic trend. A significant part of the heat flux can be convective even in pure plasmas, unlike in the plasma core, and it is sensitive to how momentum sources are distributed between the various species. In particular, if only ion momentum sources are allowed, in global simulations of pure plasmas the ion particle flux remains close to its local value, while this may not be the case for simulations with isotope mixtures or electron momentum sources. The radial angular momentum transport that is a finite orbit width effect, is found to be strongly correlated with heat sources.

  6. Element-specific density profiles in interacting biomembrane models

    Science.gov (United States)

    Schneck, Emanuel; Rodriguez-Loureiro, Ignacio; Bertinetti, Luca; Marin, Egor; Novikov, Dmitri; Konovalov, Oleg; Gochev, Georgi

    2017-03-01

    Surface interactions involving biomembranes, such as cell–cell interactions or membrane contacts inside cells play important roles in numerous biological processes. Structural insight into the interacting surfaces is a prerequisite to understand the interaction characteristics as well as the underlying physical mechanisms. Here, we work with simplified planar experimental models of membrane surfaces, composed of lipids and lipopolymers. Their interaction is quantified in terms of pressure–distance curves using ellipsometry at controlled dehydrating (interaction) pressures. For selected pressures, their internal structure is investigated by standing-wave x-ray fluorescence (SWXF). This technique yields specific density profiles of the chemical elements P and S belonging to lipid headgroups and polymer chains, as well as counter-ion profiles for charged surfaces.

  7. Reflectometry techniques for density profile measurements on fusion plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Laviron, C. [Association Euratom-CEA, Centre d`Etudes de Cadarache, 13 - Saint-Paul-lez-Durance (France). Dept. de Recherches sur la Fusion Controlee; Donne, A.J.H. [Associatie Euratom-FOM, Nieuwegein (Netherlands). FOM-Instituut voor Plasmafysica; Manso, M.E. [Instituto Superior Tecnico, Lisbon (Portugal). Lab. de Quimica Organica; Sanchez, J. [EURATOM-CIEMAT for Fusion Association, Madrid (Spain)

    1996-03-01

    Reflectometry applied to the measurement of density profiles on fusion plasmas has been subject to many recent developments. After a brief reminder of the principles of reflectometry, the theoretical accuracy of reflectometry measurements is discussed. The main difficulties limiting the performance, namely the plasma fluctuations and the quality of the transmission lines, are analysed. The different techniques used for reflectometry are then presented. The present status and achievements of actual implementations of these techniques are shown, with an analysis of their respective limitations and merits, as well as foreseen developments. (author). 70 refs.

  8. Fast electron current density profile and diffusion studies during LHCD in PBX-M

    Energy Technology Data Exchange (ETDEWEB)

    Jones, S.E.; Kesner, J.; Luckhardt, S.; Paoletti, F. [Massachusetts Inst. of Tech., Cambridge, MA (United States). Plasma Fusion Center; von Goeler, S.; Bernabei, S.; Kaita, R. [Princeton Univ., NJ (United States). Plasma Physics Lab.; Rimini, F. [JET Joint Undertaking, Abingdon (United Kingdom)

    1993-08-01

    Successful current profile control experiments using lower hybrid current drive (LCHD) clearly require knowledge of (1) the location of the driven fast electrons and (2) the ability to maintain that location from spreading due to radial diffusion. These issues can be addressed by examining the data from the hard x-ray camera on PBX-M, a unique diagnostic producing two-dimensional, time resolved tangential images of fast electron bremsstrahlung. Using modeling, these line-of-sight images are inverted to extract a radial fast electron current density profile. We note that ``hollow`` profiles have been observed, indicative of off-axis current drive. These profiles can then be used to calculate an upper bound for an effective fast electron diffusion constant: assuming an extremely radially narrow lower hybrid absorption profile and a transport model based on Rax and Moreau, a model fast electron current density profile is calculated and compared to the experimentally derived profile. The model diffusion constant is adjusted until a good match is found. Applied to steady-state quiescent modes on PBX-M, we obtain an upper limit for an effective diffusion constant of about D*=1.1 m{sup 2}/sec.

  9. Obtaining the Probability Vector Current Density in Canonical Quantum Mechanics by Linear Superposition

    CERN Document Server

    Kauffmann, Steven Kenneth

    2013-01-01

    The quantum mechanics status of the probability vector current density has long seemed to be marginal. On one hand no systematic prescription for its construction is provided, and the special examples of it that are obtained for particular types of Hamiltonian operator could conceivably be attributed to happenstance. On the other hand this concept's key physical interpretation as local average particle flux, which flows from the equation of continuity that it is supposed to satisfy in conjunction with the probability scalar density, has been claimed to breach the uncertainty principle. Given the dispiriting impact of that claim, we straightaway point out that the subtle directional nature of the uncertainty principle makes it consistent with the measurement of local average particle flux. We next focus on the fact that the unique closed-form linear-superposition quantization of any classical Hamiltonian function yields in tandem the corresponding unique linear-superposition closed-form divergence of the proba...

  10. Electron density profile measurements from hydrogen line intensity ratio method in Versatile Experiment Spherical Torus

    Science.gov (United States)

    Kim, YooSung; Shi, Yue-Jiang; Yang, Jeong-hun; Kim, SeongCheol; Kim, Young-Gi; Dang, Jeong-Jeung; Yang, Seongmoo; Jo, Jungmin; Oh, Soo-Ghee; Chung, Kyoung-Jae; Hwang, Y. S.

    2016-11-01

    Electron density profiles of versatile experiment spherical torus plasmas are measured by using a hydrogen line intensity ratio method. A fast-frame visible camera with appropriate bandpass filters is used to detect images of Balmer line intensities. The unique optical system makes it possible to take images of Hα and Hβ radiation simultaneously, with only one camera. The frame rate is 1000 fps and the spatial resolution of the system is about 0.5 cm. One-dimensional local emissivity profiles have been obtained from the toroidal line of sight with viewing dumps. An initial result for the electron density profile is presented and is in reasonable agreement with values measured by a triple Langmuir probe.

  11. Computing 1-D atomic densities in macromolecular simulations: the Density Profile Tool for VMD

    OpenAIRE

    Giorgino, Toni

    2013-01-01

    Molecular dynamics simulations have a prominent role in biophysics and drug discovery due to the atomistic information they provide on the structure, energetics and dynamics of biomolecules. Specialized software packages are required to analyze simulated trajectories, either interactively or via scripts, to derive quantities of interest and provide insight for further experiments. This paper presents the Density Profile Tool, a package that enhances the Visual Molecular Dynamics environment w...

  12. Monte Carlo Simulations of Density Profiles for Hard-Sphere Chain Fluids Confined Between Surfaces

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Covering a wide range of bulk densities, density profiles for hard-sphere chain fluids (HSCFs) with chain length of 3,4,8,20,32 and 64 confined between two surfaces were obtained by Monte Carlo simulations using extended continuum configurational-bias (ECCB) method. It is shown that the enrichment of beads near surfaces is happened at high densities due to the bulk packing effect, on the contrary, the depletion is revealed at low densities owing to the configurational entropic contribution. Comparisons with those calculated by density functional theory presented by Cai et al. indicate that the agreement between simulations and predictions is good. Compressibility factors of bulk HSCFs calculated using volume fractions at surfaces were also used to test the reliability of various equations of state of HSCFs by different authors.

  13. Mass, velocity anisotropy, and pseudo phase-space density profiles of Abell 2142

    Science.gov (United States)

    Munari, E.; Biviano, A.; Mamon, G. A.

    2014-06-01

    Aims: We aim to compute the mass and velocity anisotropy profiles of Abell 2142 and, from there, the pseudo phase-space density profile Q(r) and the density slope - velocity anisotropy β - γ relation, and then to compare them with theoretical expectations. Methods: The mass profiles were obtained by using three techniques based on member galaxy kinematics, namely the caustic method, the method of dispersion-kurtosis, and MAMPOSSt. Through the inversion of the Jeans equation, it was possible to compute the velocity anisotropy profiles. Results: The mass profiles, as well as the virial values of mass and radius, computed with the different techniques agree with one another and with the estimates coming from X-ray and weak lensing studies. A combined mass profile is obtained by averaging the lensing, X-ray, and kinematics determinations. The cluster mass profile is well fitted by an NFW profile with c = 4.0 ± 0.5. The population of red and blue galaxies appear to have a different velocity anisotropy configuration, since red galaxies are almost isotropic, while blue galaxies are radially anisotropic, with a weak dependence on radius. The Q(r) profile for the red galaxy population agrees with the theoretical results found in cosmological simulations, suggesting that any bias, relative to the dark matter particles, in velocity dispersion of the red component is independent of radius. The β - γ relation for red galaxies matches the theoretical relation only in the inner region. The deviations might be due to the use of galaxies as tracers of the gravitational potential, unlike the non-collisional tracer used in the theoretical relation.

  14. Obtaining raised density connections by thermosonic microwelding in 3D integrated microcircuits

    Directory of Open Access Journals (Sweden)

    Lanin V. L.

    2014-06-01

    Full Text Available The authors consider the processes of obtaining raised density microwelded connections in 3D-integrated microcircuits by the thermosonic microwelding. The processes include the use of the raised frequencies of ultrasound, application of the microinstrument with a thinning of the working end and precision devices for ball formation, which provide reproducibility of connections quality. At a small step of contact pads, the use of a wire of small diameter (not more than 25 µm is necessary for devices with a multilevel arrangement of leads and chess arrangement of contact pads on the chip, providing the maximum length of the formed crosspieces does not exceed 4—5 mm.

  15. Comparison of current density profiles based on particle orbit-driven current in steady-state plasma on QUEST

    Energy Technology Data Exchange (ETDEWEB)

    Alam, Md Mahbub, E-mail: m.alam@triam.kyushu-u.ac.jp [IGSES, Kyushu University, 6-1 Kasuga-koen, Kasuga, Fukuoka 816-8580 (Japan); Nakamura, Kazuo [RIAM, Kyushu University, 6-1 Kasuga-koen, Kasuga, Fukuoka 816-8580 (Japan); Xia, Fan [CFS, SWIP, P.O. Box 432, 610041 Chengdu (China); Mitarai, Osamu [Tokai University, Kumamoto 862-8652 (Japan); Hasegawa, Makoto; Tokunaga, Kazutoshi; Araki, Kuniaki; Zushi, Hideki; Hanada, Kazuaki; Fujisawa, Akihide; Idei, Hiroshi; Nagashima, Yoshihiko; Kawasaki, Shoji; Nakashima, Hisatoshi; Higashijima, Aki; Nagata, Takahiro [RIAM, Kyushu University, 6-1 Kasuga-koen, Kasuga, Fukuoka 816-8580 (Japan)

    2016-11-01

    Highlights: • Electron cyclotron resonance heating (ECRH) of QUEST. • Particle guiding center orbit calculation. • Orbit-driven current density profile. • Hollow current density. • Equilibrium condition for steady-state operation of QUEST. - Abstract: In the present RF-driven divertor plasma of QUEST, it has been observed that orbit-driven current flows in the open magnetic surfaces outside of the closed magnetic surfaces. To observe this phenomenon and the characteristics of the orbit-driven current, current density profiles have been calculated on two different equilibrium conditions. We calculated current density profiles from particle guiding center orbits both for the fundamental and the second harmonic resonances for the 8.2 GHz electron cyclotron current drive. From this calculation, hollow current density profiles have been obtained with significant characteristics on both conditions. Only positive current distribution has been observed in the open magnetic surfaces outside of the closed magnetic surfaces.

  16. Scattering length density profile of Ni film under controlled corrosion: A study in neutron reflectometry

    Indian Academy of Sciences (India)

    Surendra Singh; A K Poswal; S K Ghosh; Saibal Basu

    2008-11-01

    We report the density depth profile of an as-deposited Ni film and density profile for the same film after controlled electrochemical corrosion by chloride ions, measured by unpolarized neutron reflectometry. The neutron reflectometry measurement of the film after corrosion shows density degradation along the thickness of the film. The density profile as a function of depth, maps the growth of pitting and void networks due to corrosion. The profile after corrosion shows an interesting peaking nature.

  17. Computing 1-D atomic densities in macromolecular simulations: the Density Profile Tool for VMD

    CERN Document Server

    Giorgino, Toni

    2013-01-01

    Molecular dynamics simulations have a prominent role in biophysics and drug discovery due to the atomistic information they provide on the structure, energetics and dynamics of biomolecules. Specialized software packages are required to analyze simulated trajectories, either interactively or via scripts, to derive quantities of interest and provide insight for further experiments. This paper presents the Density Profile Tool, a package that enhances the Visual Molecular Dynamics environment with the ability to interactively compute and visualize 1-D projections of various density functions of molecular models. We describe how the plugin is used to perform computations both via a graphical interface and programmatically. Results are presented for realistic examples, all-atom bilayer models, showing how mass and electron densities readily provide measurements such as membrane thickness, location of structural elements, and how they compare to X-ray diffraction experiments.

  18. Low density ionogels obtained by rapid gellification of tetraethyl orthosilane assisted by ionic liquids.

    Science.gov (United States)

    Gupta, Abhishek Kumar; Singh, Manish Pratap; Singh, Rajendra Kumar; Chandra, Suresh

    2012-05-28

    A non-hydrolytic one pot sol-gel method has been used to synthesize mesoporous silica ionogels with the confined ionic liquid (IL) 1-ethyl 3-methyl imidazolium tetra fluoro-borate [EMIM][BF(4)]. The precursor for obtaining the SiO(2) matrix was tetraethyl orthosilicate (TEOS) and formic acid was used as a catalyst. These ionogels have been characterized by density measurements, TEM, BET, DSC, TGA and FTIR. The incorporation of the ionic liquid [EMIM][BF(4)] enhances the gellification rate which results in the ionogels having very low density (~0.3 g cm(-3)). The low density has been explained on the basis of the creation of 'blind embedded pores' in the matrix (apart from open pores) due to very rapid gellification (~1 min). Morphological studies provide experimental evidence for the presence of blind pores/voids inside the ionogel ingots. We have also shown that the IL entrapped in nanopores (~7-8 nm pore size) of the SiO(2) matrix has different physical properties than the bulk IL viz. (a) the phase transition temperatures (T(g), T(c) and T(m)) of the IL change upon confinement, (b) the thermal stability reduces upon confinement, and (c) the pore wall interaction with the IL results in changes in the C-H vibrations of the imidazolium ring and alkyl chain (the former increasing) which is also indicated in our DFT-calculation.

  19. Effect of intraband variability on stable isotope and density time series obtained from banded corals

    Indian Academy of Sciences (India)

    S Chakraborty; R Ramesh; J M Lough

    2000-03-01

    Density, 18O and 13C were measured along two tracks, one close to the central growth axis and the other, ∼20° off the axis, in a coral (Porites lutea) collected from the Stanley Reef, Central Great Barrier Reef, Australia. The 18O variations in the coral are well correlated with sea surface temperature changes. The common variances between the two tracks were about 60% in the 18O, 13C and the skeletal density variations. Part of the noise (40%) could be due to the difficulty of sampling exactly time contemporaneous parts of each band along the two tracks and part of it could be due to genuine intraband variability. In spite of the intraband variability, the time series obtained from the two tracks are similar, indicating that the dominant causative factor for the isotopic variations is external, i.e., the environmental conditions that prevail during the growth of the coral; density band formation does not appear to be directly controlled by the sea surface temperature.

  20. Validation of COSMIC radio occultation electron density profiles by incoherent scatter radar data

    Science.gov (United States)

    Cherniak, Iurii; Zakharenkova, Irina

    The COSMIC/FORMOSAT-3 is a joint US/Taiwan radio occultation mission consisting of six identical micro-satellites. Each microsatellite has a GPS Occultation Experiment payload to operate the ionospheric RO measurements. FS3/COSMIC data can make a positive impact on global ionosphere study providing essential information about height electron density distribu-tion. For correct using of the RO electron density profiles for geophysical analysis, modeling and other applications it is necessary to make validation of these data with electron density distributions obtained by another measurement techniques such as proven ground based facili-ties -ionosondes and IS radars. In fact as the ionosondes provide no direct information on the profile above the maximum electron density and the topside ionosonde profile is obtained by fitting a model to the peak electron density value, the COSMIC RO measurements can make an important contribution to the investigation of the topside part of the ionosphere. IS radars provide information about the whole electron density profile, so we can estimate the agreement of topside parts between two independent measurements. To validate the reliability of COS-MIC data we have used the ionospheric electron density profiles derived from IS radar located near Kharkiv, Ukraine (geographic coordinates: 49.6N, 36.3E, geomagnetic coordinates: 45.7N, 117.8E). The Kharkiv radar is a sole incoherent scatter facility on the middle latitudes of Eu-ropean region. The radar operates with 100-m zenith parabolic antenna at 158 MHz with peak transmitted power 2.0 MW. The Kharkiv IS radar is able to determine the heights-temporal distribution of ionosphere parameters in height range of 70-1500 km. At the ionosphere in-vestigation by incoherent scatter method there are directly measured the power spectrum (or autocorrelation function) of scattered signal. With using of rather complex procedure of the received signal processing it is possible to estimate the

  1. The combined evidential value of autosomal and Y-chromosomal DNA profiles obtained from the same sample

    NARCIS (Netherlands)

    de Zoete, J.; Sjerps, M.; Meester, R.; Cator, E.

    2014-01-01

    When a Y-chromosomal and a (partial) autosomal DNA profile are obtained from one crime sample, and both profiles match the suspect's profiles, we would like to know the combined evidential value. To calculate the likelihood ratio of observing the autosomal and Y-chromosomal DNA profiles combined, we

  2. Analytic, piecewise solution to the Lane-Emden equation for stars with complex density profiles

    Science.gov (United States)

    Miller, Jeff; Bogdanovic, Tamara

    2017-01-01

    The polytropic models of stars are used for a variety of applications in computational astrophysics. These are typically obtained by numerically solving the Lane-Emden equation for a star in hydrostatic equilibrium under assumption that the pressure and density within the star obey the polytropic equation of state. We present an efficient analytic, piecewise differentiable solution to the Lane-Emden equation which allows “stitching” of different polytropes to represent complex pressure and density profiles. This approach can be used to model stars with distinct properties in their cores and envelopes, such as the evolved red giant and horizontal branch stars.

  3. Density profile of nitrogen in cylindrical pores of MCM-41

    Science.gov (United States)

    Soper, Alan K.; Bowron, Daniel T.

    2017-09-01

    A straightforward approach using radiation scattering (X-ray or neutron) combined with atomistic modelling is used to accurately assess the pore dimensions in the porous silica, MCM-41. The method is used to calculate the density profile of nitrogen absorbed in this material at a variety of fractional pressures, p/p0, where p0 is the saturated vapour pressure, up to p/p0 = 0.36 at T = 87 K in the present instance. At this pressure two distinct layers of liquid nitrogen occur on the silica surface, with a relatively sharp gas-liquid interface. It is suggested surface tension effects at this interface strongly influence the growth of further layers.

  4. Density Profiles in Molecular Cloud Cores Associated with High-Mass Star-Forming Regions

    CERN Document Server

    Pirogov, Lev E

    2009-01-01

    Radial density profiles for the sample of dense cores associated with high-mass star-forming regions from southern hemisphere have been derived using the data of observations in continuum at 250 GHz. Radial density profiles for the inner regions of 16 cores (at distances $\\la 0.2-0.8$ pc from the center) are close on average to the $\\rho\\propto r^{-\\alpha}$ dependence, where $\\alpha=1.6\\pm 0.3$. In the outer regions density drops steeper. An analysis with various hydrostatic models showed that the modified Bonnor-Ebert model, which describes turbulent sphere confined by external pressure, is preferable compared with the logotrope and polytrope models practically in all cases. With a help of the Bonnor-Ebert model, estimates of central density in a core, non-thermal velocity dispersion and core size are obtained. The comparison of central densities with the densities derived earlier from the CS modeling reveals differences in several cases. The reasons of such differences are probably connected with the presen...

  5. Intrinsic temperature-dependent evolutions in the electron-boson spectral density obtained from optical data

    Science.gov (United States)

    Hwang, Jungseek

    2016-03-01

    We investigate temperature smearing effects on the electron-boson spectral density function (I2χ(ω)) obtained from optical data using a maximum entropy inversion method. We start with two simple model input I2χ(ω), calculate the optical scattering rates at selected temperatures using the model input spectral density functions and a generalized Allen’s formula, then extract back I2χ(ω) at each temperature from the calculated optical scattering rate using the maximum entropy method (MEM) which has been used for analysis of optical data of high-temperature superconductors including cuprates, and finally compare the resulting I2χ(ω) with the input ones. From this approach we find that the inversion process can recover the input I2χ(ω) almost perfectly when the quality of fits is good enough and also temperature smearing (or thermal broadening) effects appear in the I2χ(ω) when the quality of fits is not good enough. We found that the coupling constant and the logarithmically averaged frequency are robust to the temperature smearing effects and/or the quality of fits. We use these robust properties of the two quantities as criterions to check whether experimental data have intrinsic temperature-dependent evolutions or not. We carefully apply the MEM to two material systems (one optimally doped and the other underdoped cuprates) and conclude that the I2χ(ω) extracted from the optical data contain intrinsic temperature-dependent evolutions.

  6. Column Density Profiles of Multi-Phase Gaseous Halos

    CERN Document Server

    Liang, Cameron J; Agertz, Oscar

    2015-01-01

    We present a suite of high-resolution cosmological galaxy re-simulations of a Milky-Way size halo with variety of star-formation and feedback models to investigate the effects of the specific details of the star formation-feedback loop modeling on the observable properties of the circumgalactic medium (CGM). We show that properties of the CGM are quite sensitive to the details of star formation-feedback loop. The simulation which produces a very realistic late-type central galaxy fails to reproduce existing observations of CGM. At the same time, variations of parameters of star formation recipe or feedback modeling, such as cosmic rays feedback, brings predicted CGM in better agreement with observations. The simulations show that the column density profiles of ions arising in such gas are well described by an exponential function of the impact parameter. Ions with higher ionization energy have more extended profiles with the scale height of the exponential distribution scaling as a power law of the ionization...

  7. Implementation of the new multichannel X-mode edge density profile reflectometer for the ICRF antenna on ASDEX Upgrade

    Science.gov (United States)

    Aguiam, D. E.; Silva, A.; Bobkov, V.; Carvalho, P. J.; Carvalho, P. F.; Cavazzana, R.; Conway, G. D.; D'Arcangelo, O.; Fattorini, L.; Faugel, H.; Fernandes, A.; Fünfgelder, H.; Gonçalves, B.; Guimarais, L.; De Masi, G.; Meneses, L.; Noterdaeme, J. M.; Pereira, R. C.; Rocchi, G.; Santos, J. M.; Tuccillo, A. A.; Tudisco, O.

    2016-11-01

    A new multichannel frequency modulated continuous-wave reflectometry diagnostic has been successfully installed and commissioned on ASDEX Upgrade to measure the plasma edge electron density profile evolution in front of the Ion Cyclotron Range of Frequencies (ICRF) antenna. The design of the new three-strap ICRF antenna integrates ten pairs (sending and receiving) of microwave reflectometry antennas. The multichannel reflectometer can use three of these to measure the edge electron density profiles up to 2 × 1019 m-3, at different poloidal locations, allowing the direct study of the local plasma layers in front of the ICRF antenna. ICRF power coupling, operational effects, and poloidal variations of the plasma density profile can be consistently studied for the first time. In this work the diagnostic hardware architecture is described and the obtained density profile measurements were used to track outer radial plasma position and plasma shape.

  8. Implementation of the new multichannel X-mode edge density profile reflectometer for the ICRF antenna on ASDEX Upgrade

    Energy Technology Data Exchange (ETDEWEB)

    Aguiam, D. E., E-mail: daguiam@ipfn.tecnico.ulisboa.pt; Silva, A.; Carvalho, P. J.; Carvalho, P. F.; Fernandes, A.; Gonçalves, B.; Guimarais, L.; Meneses, L.; Pereira, R. C.; Santos, J. M. [Instituto de Plasmas e Fusão Nuclear, Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa (Portugal); Bobkov, V.; Conway, G. D.; Faugel, H.; Fünfgelder, H. [Max-Planck-Institut für Plasmaphysik, Boltzmannstr. 2, D-85748 Garching (Germany); Cavazzana, R.; De Masi, G. [Consorzio RFX (CNR, ENEA, INFN, Universitá di Padova, Acciaierie Venete SpA), Corso Stati Uniti 4, 35127 Padova (Italy); D’Arcangelo, O.; Rocchi, G.; Tuccillo, A. A. [ENEA, Dipartimento FSN, C. R. Frascati, Via E. Fermi 45, 00044 Frascati, Roma (Italy); and others

    2016-11-15

    A new multichannel frequency modulated continuous-wave reflectometry diagnostic has been successfully installed and commissioned on ASDEX Upgrade to measure the plasma edge electron density profile evolution in front of the Ion Cyclotron Range of Frequencies (ICRF) antenna. The design of the new three-strap ICRF antenna integrates ten pairs (sending and receiving) of microwave reflectometry antennas. The multichannel reflectometer can use three of these to measure the edge electron density profiles up to 2 × 10{sup 19} m{sup −3}, at different poloidal locations, allowing the direct study of the local plasma layers in front of the ICRF antenna. ICRF power coupling, operational effects, and poloidal variations of the plasma density profile can be consistently studied for the first time. In this work the diagnostic hardware architecture is described and the obtained density profile measurements were used to track outer radial plasma position and plasma shape.

  9. Mapping Bone Mineral Density Obtained by Quantitative Computed Tomography to Bone Volume Fraction

    Science.gov (United States)

    Pennline, James A.; Mulugeta, Lealem

    2017-01-01

    Methods for relating or mapping estimates of volumetric Bone Mineral Density (vBMD) obtained by Quantitative Computed Tomography to Bone Volume Fraction (BVF) are outlined mathematically. The methods are based on definitions of bone properties, cited experimental studies and regression relations derived from them for trabecular bone in the proximal femur. Using an experimental range of values in the intertrochanteric region obtained from male and female human subjects, age 18 to 49, the BVF values calculated from four different methods were compared to the experimental average and numerical range. The BVF values computed from the conversion method used data from two sources. One source provided pre bed rest vBMD values in the intertrochanteric region from 24 bed rest subject who participated in a 70 day study. Another source contained preflight vBMD values from 18 astronauts who spent 4 to 6 months on the ISS. To aid the use of a mapping from BMD to BVF, the discussion includes how to formulate them for purpose of computational modeling. An application of the conversions would be used to aid in modeling of time varying changes in vBMD as it relates to changes in BVF via bone remodeling and/or modeling.

  10. Anti-Viral Antibody Profiling by High Density Protein Arrays

    Science.gov (United States)

    Bian, Xiaofang; Wiktor, Peter; Kahn, Peter; Brunner, Al; Khela, Amritpal; Karthikeyan, Kailash; Barker, Kristi; Yu, Xiaobo; Magee, Mitch; Wasserfall, Clive H.; Gibson, David; Rooney, Madeleine E; Qiu, Ji; LaBaer, Joshua

    2015-01-01

    Viral infections elicit anti-viral antibodies and have been associated with various chronic diseases. Detection of these antibodies can facilitate diagnosis, treatment of infection and understanding of the mechanisms of virus associated diseases. In this work, we assayed anti-viral antibodies using a novel high density-nucleic acid programmable protein array (HD-NAPPA) platform. Individual viral proteins were expressed in situ directly from plasmids encoding proteins in an array of microscopic reaction chambers. Quality of protein display and serum response was assured by comparing intra- and inter- array correlation within or between printing batches with average correlation coefficients of 0.91 and 0.96, respectively. HD-NAPPA showed higher signal to background (S/B) ratio compared with standard NAPPA on planar glass slides and ELISA. Antibody responses to 761 antigens from 25 different viruses were profiled among patients with juvenile idiopathic arthritis (JIA) and type 1 diabetes (T1D). Common as well as unique antibody reactivity patterns were detected between patients and healthy controls. We believe HD-viral-NAPPA will enable the study of host-pathogen interactions at unprecedented dimensions and elucidate the role of pathogen infections in disease development. PMID:25758251

  11. Evolution of Characteristic Quantities for Dark Matter Halo Density Profiles

    CERN Document Server

    Romano-Diaz, E; Heller, C; Faltenbacher, A; Jones, D; Shlosman, I; Romano-Diaz, Emilio; Hoffman, Yehuda; Heller, Clayton; Faltenbacher, Andreas; Jones, Daniel; Shlosman, Isaac

    2006-01-01

    We investigate the effect of an assembly history on the evolution of dark matter (DM) halos of 10^{12} Msun/h using Constrained Realizations of random Gaussian fields. Five different realizations of a DM halo with distinct merging histories were constructed and evolved. Our main results are: A halo evolves via a sequence of quiescent phases of a slow mass accretion intermitted by violent episodes of major mergers. In the quiescent phases, the density is well fitted by an NFW profile, the inner scale radius Rs and the mass enclosed within it remain constant, and the virial radius (Rvir) grows linearly with the expansion parameter "a". Within each quiescent phase the concentration parameter ("c") scales as "a", and the mass accretion history (Mvir) is well described by the Tasitsiomi etal. fitting formula. In the violent phases the halos are not in a virial equilibrium and both Rs and Rvir grow discontinuously. The violent episodes drive the halos from one NFW dynamical equilibrium to another. The final structu...

  12. Measuring protoplanetary disk gas surface density profiles with ALMA

    CERN Document Server

    McPartland, Jonathan P Williams Conor

    2016-01-01

    The gas and dust are spatially segregated in protoplanetary disks due to the vertical settling and radial drift of large grains. A fuller accounting of the mass content and distribution in disks therefore requires spectral line observations. We extend the modeling approach presented in Williams & Best (2014) to show that gas surface density profiles can be measured from high fidelity 13CO integrated intensity images. We demonstrate the methodology by fitting ALMA observations of the HD 163296 disk to determine a gas mass, Mgas = 0.048 solar masse, and accretion disk characteristic size Rc = 213au and gradient gamma = 0.39. The same parameters match the C18O 2--1 image and indicates an abundance ratio [13CO]/[C18O] of 700 independent of radius. To test how well this methodology can be applied to future line surveys of smaller, lower mass T Tauri disks, we create a large 13CO 2--1 image library and fit simulated data. For disks with gas masses 3-10 Jupiter masses at 150pc, ALMA observations with a resolutio...

  13. CO{sub 2} laser diagnostics for measurements of the plasma density profile and plasma density fluctuations on LHD

    Energy Technology Data Exchange (ETDEWEB)

    Vyacheslavov, L.N. [Budker Institute of Nuclear Physics, Novosibirsk (Russian Federation); Tanaka, K.; Kawahata, K. [National Inst. for Fusion Science, Toki, Gifu (Japan)

    2001-04-01

    A CO{sub 2} laser based diagnostics complimentary to the existing FIR interferometer is proposed. It combines interferometry for plasma density profile measurement under conditions of large density gradients, and both imaging and scattering techniques for observation of plasma fluctuations. Two-colour interferometer with a slablike probe beam and a single multichannel linear detector array provide observation of plasma density profile and density fluctuations at two locations along the probe beam. Basic characteristics of the diagnostics are considered as well as some effects that include dispersion and are critical for two colour imaging technique. The results of the bench-top experiments with the prototype of the interferometer are presented. (author)

  14. Role of Density Profiles for the Nonlinear Propagation of Intense Laser Beam through Plasma Channel

    OpenAIRE

    Sonu Sen; Meenu Asthana Varshney; Dinesh Varshney

    2014-01-01

    In this work role of density profiles for the nonlinear propagation of intense laser beam through plasma channel is analyzed. By employing the expression for the dielectric function of different density profile plasma, a differential equation for beamwidth parameter is derived under WKB and paraxial approximation. The laser induces modifications of the dielectric function through nonlinearities. It is found that density profiles play vital role in laser-plasma interaction studies. To have num...

  15. Simple Method Obtaining Analytical Expressions of Particle and Kinetic—Energy Densities for One—Dimensional Confined Fermi Gases

    Institute of Scientific and Technical Information of China (English)

    YANGXiao-Xue; WUYing

    2002-01-01

    We develop a simple approach to obtain explicitly exact analytical expressions of particle and kineticenergy densities for noninteracting Fermi gases in one-dimensional harmonic confinement,and in one-dimensional box confinement as well.

  16. Simple Method Obtaining Analytical Expressions of Particle and Kinetic-Energy Densities for One-Dimensional Confined Fermi Gases

    Institute of Scientific and Technical Information of China (English)

    YANG XiaoXue; WU Ying

    2002-01-01

    We develop a simple approach to obtain explicitly exact analytical expressions of particle and kinetic-energy densities for noninteracting Fermi gases in one-dimensional harmonic confinement, and in one-dimensional boxconfinement as well.

  17. Ground-State Density Profiles of One-Dimensional Bose Gases with Anisotropic Transversal Confinement

    Institute of Scientific and Technical Information of China (English)

    HAO Ya-Jiang

    2011-01-01

    We investigate the ground-state density distributions of interacting one-dimensional Bose gases with anisotropic transversal confinement.Combining the exact ground state energy density of homogeneous bose gases with local density approximation,we determine the density distribution in each interacting regime for different anisotropic parameters.It is shown that the transversal anisotropic parameter changes the density distribution obviously,and the observed density profiles on each orientation exhibit a difference of a factor.

  18. Statistical Analysis of the Spectral Density Estimate Obtained via Coifman Scaling Function

    OpenAIRE

    2007-01-01

    Spectral density built as Fourier transform of covariance sequence of stationary random process is determining the process characteristics and makes for analysis of it’s structure. Thus, one of the main problems in time series analysis is constructing consistent estimates of spectral density via successive, taken after equal periods of time observations of stationary random process. This article is devoted to investigation of problems dealing with application of wavelet anal...

  19. An Estimate of Solar Wind Density and Velocity Profiles in a Coronal Hole and a Coronal Streamer

    Science.gov (United States)

    Patzold, M.; Tsurutani, B. T.; Bird, M. K.

    1996-01-01

    Using the total electron content data obtained by the Ulysses Solar Corona Experiment (SCE) during the first solar conjunction in summer 1991, two data sets were selected, one associated with a coronal hole and the other associated with coronal streamer crossings. In order to determine coronal streamer density profiles, the electron content of the tracking passes embedded in a coronal streamer were corrected for the contributions from coronal hole densities.

  20. Geometrically necessary dislocation densities in olivine obtained using high-angular resolution electron backscatter diffraction.

    Science.gov (United States)

    Wallis, David; Hansen, Lars N; Ben Britton, T; Wilkinson, Angus J

    2016-09-01

    Dislocations in geological minerals are fundamental to the creep processes that control large-scale geodynamic phenomena. However, techniques to quantify their densities, distributions, and types over critical subgrain to polycrystal length scales are limited. The recent advent of high-angular resolution electron backscatter diffraction (HR-EBSD), based on diffraction pattern cross-correlation, offers a powerful new approach that has been utilised to analyse dislocation densities in the materials sciences. In particular, HR-EBSD yields significantly better angular resolution (olivine, the dominant mineral in Earth's upper mantle by testing (1) different inversion methods for estimating geometrically necessary dislocation (GND) densities, (2) the sensitivity of the method under a range of data acquisition settings, and (3) the ability of the technique to resolve a variety of olivine dislocation structures. The relatively low crystal symmetry (orthorhombic) and few slip systems in olivine result in well constrained GND density estimates. The GND density noise floor is inversely proportional to map step size, such that datasets can be optimised for analysing either short wavelength, high density structures (e.g. subgrain boundaries) or long wavelength, low amplitude orientation gradients. Comparison to conventional images of decorated dislocations demonstrates that HR-EBSD can characterise the dislocation distribution and reveal additional structure not captured by the decoration technique. HR-EBSD therefore provides a highly effective method for analysing dislocations in olivine and determining their role in accommodating macroscopic deformation.

  1. Determination of stratospheric temperature and density by GOMOS: Verification with respect to high latitude LIDAR profiles from Thule, Greenland

    Science.gov (United States)

    di Sarra, A.; Iannone, R. Q.; Casadio, S.; Di Biagio, C.; Pace, G.; Cacciani, M.; Muscari, G.; Dehn, A.; Bojkov, B.

    2017-02-01

    High resolution temperature profiles (HRTP) have been derived from measurements performed by Global Ozone Monitoring by Occultation of Stars (GOMOS) onboard ENVISAT. HRTP are derived from measurements with two fast photometers whose signal is sampled at 1 kHz, and allows investigating the role of irregularities in the density and temperature profiles, such as those associated with gravity waves. In this study high resolution temperature and density profiles measured at high latitude by GOMOS are compared with observations made with the ground-based aerosol/temperature LIDAR at Thule, Greenland. The LIDAR at Thule contributes to the Network for the Detection of Atmospheric Composition Change. The LIDAR profiles are analyzed in the height interval overlapping with GOMOS data (22-35 km), and the density and temperature profiles are obtained with 250 m vertical resolution. The comparison is focused on data collected during the 2008-2009 and 2009-2010 Arctic winters. Profiles measured within 6 hours and 500 km are selected. The profiles are classified based on spatial and temporal variability of dynamical indicators over Thule and at the GOMOS tangent height position. Several corresponding features can be identified in the GOMOS and LIDAR profiles, suggesting that the GOMOS HRTP could be used to investigate the global distribution of small scale fluctuations. As an example, two cases corresponding to inner and outer vortex conditions during the 2008-2009 winter are discussed, also in relation with the very intense sudden stratospheric warming occurred in this season.

  2. Modelling of the electron density height profiles in the mid-latitude ionospheric D-region

    Directory of Open Access Journals (Sweden)

    P. Y. Mukhtarov

    1996-06-01

    Full Text Available A new mid-latitude D-region (50-105 km model of the electron density is presented obtained on the basis of a full wave theory and by a trial-and-error inversion method. Daytime (at different solar zenith angles absorption measurements by A3-technique made in Bulgaria yielded data with the aid of which the seasonal and diurnal courses of the Ne(h-profiles were derived. Special attention is drawn to the event diurnal asymmetry, or uneven formation of the ionosphere as a function of insulation. The latter is probably connected with the influence of the diurnal fluctuations in the local temperature on the chemistry involved in the electron loss rate, as well as the diurnal variations of the main ionizing agent (NO in the D-region. That is why the Ne(h-profiles in the midlatitude D-region are modelled separately for morning and afternoon hours.

  3. Geometrically necessary dislocation densities in olivine obtained using high-angular resolution electron backscatter diffraction

    Energy Technology Data Exchange (ETDEWEB)

    Wallis, David, E-mail: davidwa@earth.ox.ac.uk [Department of Earth Sciences, University of Oxford, South Parks Road, Oxford, Oxfordshire, OX1 3AN (United Kingdom); Hansen, Lars N. [Department of Earth Sciences, University of Oxford, South Parks Road, Oxford, Oxfordshire, OX1 3AN (United Kingdom); Ben Britton, T. [Department of Materials, Imperial College London, Royal School of Mines, Exhibition Road, London SW7 2AZ (United Kingdom); Wilkinson, Angus J. [Department of Materials, University of Oxford, Parks Road, Oxford, Oxfordshire, OX1 3PH (United Kingdom)

    2016-09-15

    Dislocations in geological minerals are fundamental to the creep processes that control large-scale geodynamic phenomena. However, techniques to quantify their densities, distributions, and types over critical subgrain to polycrystal length scales are limited. The recent advent of high-angular resolution electron backscatter diffraction (HR-EBSD), based on diffraction pattern cross-correlation, offers a powerful new approach that has been utilised to analyse dislocation densities in the materials sciences. In particular, HR-EBSD yields significantly better angular resolution (<0.01°) than conventional EBSD (~0.5°), allowing very low dislocation densities to be analysed. We develop the application of HR-EBSD to olivine, the dominant mineral in Earth's upper mantle by testing (1) different inversion methods for estimating geometrically necessary dislocation (GND) densities, (2) the sensitivity of the method under a range of data acquisition settings, and (3) the ability of the technique to resolve a variety of olivine dislocation structures. The relatively low crystal symmetry (orthorhombic) and few slip systems in olivine result in well constrained GND density estimates. The GND density noise floor is inversely proportional to map step size, such that datasets can be optimised for analysing either short wavelength, high density structures (e.g. subgrain boundaries) or long wavelength, low amplitude orientation gradients. Comparison to conventional images of decorated dislocations demonstrates that HR-EBSD can characterise the dislocation distribution and reveal additional structure not captured by the decoration technique. HR-EBSD therefore provides a highly effective method for analysing dislocations in olivine and determining their role in accommodating macroscopic deformation. - Highlights: • Lattice orientation gradients in olivine were measured using HR-EBSD. • The limited number of olivine slip systems enable simple least squares inversion for GND

  4. Evolution of density and velocity profiles of dark matter and dark energy in spherical voids

    CERN Document Server

    Novosyadlyj, Bohdan; Kulinich, Yurij

    2016-01-01

    We analyse the evolution of cosmological perturbations which leads to the formation of large isolated voids in the Universe. We assume that initial perturbations are spherical and all components of the Universe (radiation, matter and dark energy) are continuous media with perfect fluid energy-momentum tensors, which interact only gravitationally. Equations of the evolution of perturbations for every component in the comoving to cosmological background reference frame are obtained from equations of energy and momentum conservation and Einstein's ones and are integrated numerically. Initial conditions are set at the early stage of evolution in the radiation-dominated epoch, when the scale of perturbation is much larger than the particle horizon. Results show how the profiles of density and velocity of matter and dark energy are formed and how they depend on parameters of dark energy and initial conditions. In particular, it is shown that final matter density and velocity amplitudes change within range $\\sim$4-7...

  5. Computational model of abiogenic amino acid condensation to obtain a polar amino acid profile.

    Science.gov (United States)

    Polanco, Carlos; Buhse, Thomas; Samaniego, José Lino; Castañón González, Jorge Alberto; Arias Estrada, Miguel

    2014-01-01

    In accordance with the second law of thermodynamics, the Universe as a whole tends to higher entropy. However, the sequence of far-from-equilibrium events that led to the emergence of life on Earth could have imposed order and complexity during the course of chemical reactions in the so-called primordial soup of life. Hence, we may expect to find characteristic profiles or biases in the prebiotic product mixtures, as for instance among the first amino acids. Seeking to shed light on this hypothesis, we have designed a high performance computer program that simulates the spontaneous formation of the amino acid monomers in closed environments. The program was designed in reference to a prebiotic scenario proposed by Sydney W. Fox. The amino acid abundances and their polarities as the two principal biases were also taken into consideration. We regarded the computational model as exhaustive since 200,000 amino acid dimers were formed by simulation, subsequently expressed in a vector and compared with the corresponding amino acid dimers that were experimentally obtained by Fox. We found a very high similarity between the experimental results and our simulations.

  6. High-Latitude Topside Ionospheric Vertical Electron Density Profile Changes in Response to Large Magnetic Storms

    Science.gov (United States)

    Benson, Robert F.; Fainberg, Joseph; Osherovich, Vladimir A.; Truhlik, Vladimir; Wang, Yongli; Bilitza, Dieter; Fung, Shing F.

    2016-01-01

    Large magnetic-storm-induced changes were detected in high-latitude topside vertical electron density profiles Ne(h) in a database of profiles and digital topside ionograms, from the International Satellites for Ionospheric Studies (ISIS) program, that enabled Ne(h) profiles to be obtained in nearly the same region of space before, during, and after a major magnetic storm (Dst -100nT). Storms where Ne(h) profiles were available in the high-latitude Northern Hemisphere had better coverage of solar wind parameters than storms with available Ne(h) profiles in the high-latitude Southern Hemisphere. Large Ne(h) changes were observed during all storms, with enhancements and depletions sometimes near a factor of 10 and 0.1, respectively, but with substantial differences in the responses in the two hemispheres. Large spatial andor temporal Ne(h) changes were often observed during Dst minimum and during the storm recovery phase. The storm-induced Ne(h) changes were the most pronounced and consistent in the Northern Hemisphere in that large enhancements were observed during winter nighttime and large depletions during winter and spring daytime. The limited available cases suggested that these Northern Hemisphere enhancements increased with increases of the time-shifted solar wind velocity v, magnetic field B, and with more negative values of the B components except for the highest common altitude (1100km) of the profiles. There was also some evidence suggesting that the Northern Hemisphere depletions were related to changes in the solar wind parameters. Southern Hemisphere storm-induced enhancements and depletions were typically considerably less with depletions observed during summer nighttime conditions and enhancements during summer daytime and fall nighttime conditions.

  7. Asymmetric Velocity Distributions from Halo Density Profiles in the Eddington Approach

    Directory of Open Access Journals (Sweden)

    J. D. Vergados

    2015-01-01

    Full Text Available We show how to obtain the energy distribution f(E in our vicinity starting from WIMP density profiles in a self-consistent way by employing the Eddington approach and adding reasonable angular momentum dependent terms in the expression of the energy. We then show how we can obtain the velocity dispersions and the asymmetry parameter β in terms of the parameters describing the angular momentum dependence. From this expression, for f(E, we proceed to construct an axially symmetric WIMP a velocity distribution, which, for a gravitationally bound system, automatically has a velocity upper bound and is characterized by the same asymmetriy β. This approach is tested and clarified by constructing analytic expressions in a simple model, with adequate structure. We then show how such velocity distributions can be used in determining the event rates, including modulation, in both the standard and the directional WIMP searches.

  8. Factors influencing the density profiles of granular flux in a two-dimensional inclined channel

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    The two-dimensional dilute granular flow on a smooth incline bounded by rough sidewalls is investigated experimentally, and the transverse density profiles of granular flux (ξ = ρ v) across the channel are measured. The results show that the transverse density profiles of granular flux are symmetric about the channel center and that the density of granular flux near the boundary is clearly lower than that of the center. There is a critical width of channel Wc for the transition of the density of granular flux. The density of granular flux near the boundary decays with the increasing of inclination (sinθ ) of the channel.

  9. Factors influencing the density profiles of granular flux in a two-dimensional inclined channel

    Institute of Scientific and Technical Information of China (English)

    BAO DeSong; ZHOU Ying; ZHANG XunSheng; TANG XiaoWei

    2009-01-01

    The two-dimensional dilute granular flow on a smooth incline bounded by rough sidewalls is investigated experimentally, and the transverse density profiles of granular flux (ξ=pv) across the channel are measured. The results show that the transverse density profiles of granular flux are symmetric about the channel center and that the density of granular flux near the boundary is clearly lower than that of the center. There is a critical width of channel Wc for the transition of the density of granular flux. The density of granular flux near the boundary decays with the increasing of inclination (sinθ) of the channel.

  10. Comparison of the Volume Charge Density of Nanofiltration Membranes Obtained from Retention and Conductivity Experiments

    DEFF Research Database (Denmark)

    Benavente, J.; Silva, V.; Pradanos, P.

    2010-01-01

    A version of the Donnan steric-partitioning pore model with dielectrical exclusion (DSPM-DE) has been used to get information on the pore size and charge density of a commercial membrane, NF45 from FilmTec, from its retention of KCl solutions. The conductivity inside the pores has been measured...... of the membrane. These two methods give results in fair accordance which probes that the sometimes controversial method of DSPM-DE can give accurate results for the charge as well as for the mean pore size of a nanofiltration membrane. Sonic clues to improve the way this model can be used are given as well....

  11. Seminal plasma protein profiles of ejaculates obtained by internal artificial vagina and electroejaculation in Brahman bulls.

    Science.gov (United States)

    Rego, J P A; Moura, A A; Nouwens, A S; McGowan, M R; Boe-Hansen, G B

    2015-09-01

    The present study was conducted to investigate if differences exist in the seminal plasma protein profile from mature Brahman bulls using two methods of semen collection: internal artificial vagina (IAV) and electroejaculation (EEJ). Semen was collected four times from three bulls on the same day and parameters were assessed immediately post-collection. Seminal plasma proteins were evaluated by 2-D fluorescence difference gel electrophoresis and identified by mass spectrometry. Semen volume was greater (P < 0.05) for EEJ (4.6 ± 0.35 mL) than for IAV (1.86 ± 0.24 mL) but sperm concentration was greater in IAV (1505 ± 189 × 10(6) sperm/mL) than in EEJ samples (344 ± 87 × 10(6) sperm/mL). Sperm motility and the percentage of normal sperm were not different between treatments. Total concentration of seminal plasma proteins was greater for samples collected by IAV as compared to EEJ (19.3 ± 0.9 compared with 13.0 ± 1.8 mg/mL, P < 0.05; respectively). Based on 2-D gels, 22 spots had a greater volume (P < 0.05) in gels derived from IAV samples, corresponding to 21 proteins identified as transferrin, albumin, epididymal secretory glutathione peroxidase, among others. Thirty-three spots, corresponding to 26 proteins, had a greater volume (P < 0.05) in gels derived from EEJ samples. These proteins were identified as spermadhesin-1, Bovine Sperm Protin 1, 3 and 5 isoforms, angiogenin-1, alpha-1B-glycoprotein, clusterin, nucleobindin-1, cathepsins, spermadhesin Z13, annexins, among others. Thus, proteins in greater amounts in samples obtained by IAV and EEJ were mainly of epididymal origin and accessory sex glands, respectively. Copyright © 2015 Elsevier B.V. All rights reserved.

  12. Stellar density profile and mass of the Milky Way Bulge from VVV data

    CERN Document Server

    Valenti, E; Gonzalez, O A; Minniti, D; Alonso-Garcia, J; Marchetti, E; Hempel, M; Renzini, A; Rejkuba, M

    2015-01-01

    We present the first stellar density profile of the Milky Way bulge reaching latitude $b=0^\\circ$. It is derived by counting red clump stars within the colour\\--magnitude diagram constructed with the new PSF-fitting photometry from VISTA Variables in the V\\'\\i a L\\'actea (VVV) survey data. The new stellar density map covers the area between $|l|\\leq 10^\\circ$ and $|b|\\leq 4.5^\\circ$ with unprecedented accuracy, allowing to establish a direct link between the stellar kinematics from the Giraffe Inner Bulge Spectroscopic Survey (GIBS) and the stellar mass density distribution. In particular, the location of the central velocity dispersion peak from GIBS matches a high overdensity in the VVV star count map. By scaling the total luminosity function (LF) obtained from all VVV fields to the LF from Zoccali et al.(2003), we obtain the first fully empirical estimate of the mass in stars and remnants of the Galactic bulge. The Milky Way bulge stellar mass within ($|b|<9.5^\\circ$, $|l|<10^\\circ$) is $2.0\\pm0.3\\ti...

  13. Mechanical properties of low density polymeric foams obtained from full-field measurements

    Directory of Open Access Journals (Sweden)

    Pierron F.

    2010-06-01

    Full Text Available This exploratory paper presents some preliminary results on the use of fullfield deformation measurements on low density polymeric foams to identify the evolution of Poisson’s ratio with compressive strain. Two types of foams were tested: a standard low density polyurethane foam and an auxetic foam manufactured from a similar precursor. 2D digital image correlation was used to measure the strain field at the specimens surfaces. Then, Poisson’s ratios were identified using a dedicated inverse method called the Virtual Fields Method (VFM and the results compared with the standard approaches. The results illustrate the advantages of the VFM compared to the standard procedure. It was also found that for the standard foam, very strong localization effects resulted in biased Poisson’s ratio evaluation. It was shown that this could be corrected by taking into account these localization effects thanks to the full-field information.

  14. Kernel density estimation of a multidimensional efficiency profile

    CERN Document Server

    Poluektov, Anton

    2014-01-01

    Kernel density estimation is a convenient way to estimate the probability density of a distribution given the sample of data points. However, it has certain drawbacks: proper description of the density using narrow kernels needs large data samples, whereas if the kernel width is large, boundaries and narrow structures tend to be smeared. Here, an approach to correct for such effects, is proposed that uses an approximate density to describe narrow structures and boundaries. The approach is shown to be well suited for the description of the efficiency shape over a multidimensional phase space in a typical particle physics analysis. An example is given for the five-dimensional phase space of the $\\Lambda_b^0\\to D^0p\\pi$ decay.

  15. A microscopic "social norm" model to obtain realistic macroscopic velocity and density pedestrian distributions.

    Directory of Open Access Journals (Sweden)

    Francesco Zanlungo

    Full Text Available We propose a way to introduce in microscopic pedestrian models a "social norm" in collision avoiding and overtaking, i.e. the tendency, shared by pedestrians belonging to the same culture, to avoid collisions and perform overtaking in a preferred direction. The "social norm" is implemented, regardless of the specific collision avoiding model, as a rotation in the perceived velocity vector of the opponent at the moment of computation of the collision avoiding strategy, and justified as an expectation that the opponent will follow the same "social norm" (for example a tendency to avoid on the left and overtake on the right, as proposed in this work for Japanese pedestrians. By comparing with real world data, we show that the introduction of this norm allows for a better reproduction of macroscopic pedestrian density and velocity patterns.

  16. A Bone Sample Containing a Bone Graft Substitute Analyzed by Correlating Density Information Obtained by X-ray Micro Tomography with Compositional Information Obtained by Raman Microscopy

    Directory of Open Access Journals (Sweden)

    Johann Charwat-Pessler

    2015-06-01

    Full Text Available The ability of bone graft substitutes to promote new bone formation has been increasingly used in the medical field to repair skeletal defects or to replace missing bone in a broad range of applications in dentistry and orthopedics. A common way to assess such materials is via micro computed tomography (µ-CT, through the density information content provided by the absorption of X-rays. Information on the chemical composition of a material can be obtained via Raman spectroscopy. By investigating a bone sample from miniature pigs containing the bone graft substitute Bio Oss®, we pursued the target of assessing to what extent the density information gained by µ-CT imaging matches the chemical information content provided by Raman spectroscopic imaging. Raman images and Raman correlation maps of the investigated sample were used in order to generate a Raman based segmented image by means of an agglomerative, hierarchical cluster analysis. The resulting segments, showing chemically related areas, were subsequently compared with the µ-CT image by means of a one-way ANOVA. We found out that to a certain extent typical gray-level values (and the related histograms in the µ-CT image can be reliably related to specific segments within the image resulting from the cluster analysis.

  17. Plasma Shape and Current Density Profile Control in Advanced Tokamak Operating Scenarios

    Science.gov (United States)

    Shi, Wenyu

    The need for new sources of energy is expected to become a critical problem within the next few decades. Nuclear fusion has sufficient energy density to potentially supply the world population with its increasing energy demands. The tokamak is a magnetic confinement device used to achieve controlled fusion reactions. Experimental fusion technology has now reached a level where tokamaks are able to produce about as much energy as is expended in heating the fusion fuel. The next step towards the realization of a nuclear fusion tokamak power plant is ITER, which will be capable of exploring advanced tokamak (AT) modes, characterized by a high fusion gain and plasma stability. The extreme requirements of the advanced modes motivates researchers to improve the modeling of the plasma response as well as the design of feedback controllers. This dissertation focuses on several magnetic and kinetic control problems, including the plasma current, position and shape control, and data-driven and first-principles-driven modeling and control of plasma current density profile and the normalized plasma pressure ratio betaN. The plasma is confined within the vacuum vessel by an external electromagnetic field, produced primarily by toroidal and poloidal field coils. The outermost closed plasma surface or plasma boundary is referred to as the shape of the plasma. A central characteristic of AT plasma regimes is an extreme elongated shape. The equilibrium among the electromagnetic forces acting on an elongated plasma is unstable. Moreover, the tokamak performance is improved if the plasma is located in close proximity to the torus wall, which guarantees an efficient use of available volume. As a consequence, feedback control of the plasma position and shape is necessary. In this dissertation, an Hinfinity-based, multi-input-multi-output (MIMO) controller for the National Spherical Torus Experiment (NSTX) is developed, which is used to control the plasma position, shape, and X

  18. Explaining the density profile of self-gravitating systems by statistical mechanics

    Science.gov (United States)

    Kang, Dong-Biao

    A self-gravitating system usually shows a quasi-universal density profile, such as the NFW profile of a simulated dark matter halo, the flat rotation curve of a spiral galaxy, the Sérsic profile of an elliptical galaxy, the King profile of a globular cluster and the exponential law of the stellar disk. It will be interesting if all of the above can be obtained from first principles. Based on the original work of White & Narayan (1987), we propose that if the self-bounded system is divided into infinite infinitesimal subsystems, the entropy of each subsystem can be maximized, but the whole system's gravity may just play the role of the wall, which may not increase the whole system's entropy S t , and finally S t may be the minimum among all of the locally maximized entropies (He & Kang 2010). For spherical systems with isotropic velocity dispersion, the form of the equation of state will be a hybrid of isothermal and adiabatic (Kang & He 2011). Hence this density profile can be approximated by a truncated isothermal sphere, which means that the total mass must be finite and our results can be consistent with observations (Kang & He 2011b). Our method requires that the mass and energy should be conserved, so we only compare our results with simulations of mild relaxation (i.e. the virial ratio is close to -1) of dissipationless collapse (Kang 2014), and the fitting also is well. The capacity can be calculated and is found not to be always negative as in previous works, and combining with calculations of the second order variation of the entropy, we find that the thermodynamical stability still can be true (Kang 2012) if the temperature tends to be zero. However, the cusp in the center of dark matter halos can not be explained, and more works will continue. The above work can be generalized to study the radial distribution of the disk (Kang 2015). The energy constraint automatically disappears in our variation, because angular momentum is much more important than

  19. A simple method of obtaining concentration depth-profiles from X-ray diffraction

    Science.gov (United States)

    Wiedemann, K. E.; Unnam, J.

    1984-01-01

    The construction of composition profiles from X-ray intensity bands was investigated. The intensity band-to-composition profile transformation utilizes a solution which can be easily evaluated. The technique can be applied to thin films and thick speciments for which the variation of lattice parameters, linear absorption coefficient, and reflectivity with composition are known. A deconvolution scheme with corrections for the instrumental broadening and ak-alfadoublet is discussed.

  20. Type II diabetes patients in primary care: profiles of healthcare utilization obtained from observational data

    Directory of Open Access Journals (Sweden)

    van Dijk Christel E

    2013-01-01

    Full Text Available Abstract Background The high burden of diabetes for healthcare costs and their impact on quality of life and management of the disease have triggered the design and introduction of disease management programmes (DMPs in many countries. The extent to which diabetes patients vary with regard to their healthcare utilisation and costs is largely unknown and could impact on the design of DMPs. The objectives of this study are to develop profiles based on both the diabetes-related healthcare utilisation and total healthcare utilisation in primary care, to investigate which patient and disease characteristics determine ‘membership’ of each profile, and to investigate the association between these profiles. Methods Data were used from electronic medical records of 6721 known type II diabetes patients listed in 48 Dutch general practices. Latent Class Analyses were conducted to identify profiles of healthcare and regression analyses were used to analyse the characteristics of the profiles. Results For both diabetes-related healthcare utilisation and total healthcare utilisation three profiles could be distinguished: for the diabetes-related healthcare utilisation these were characterised as ‘high utilisation and frequent home visits’ (n=393, ‘low utilisation, GP only’ (n=3231 and ‘high utilisation, GP and nurse’ (n=3097. Profiles differed with respect to the patients’ age and type of medication; the oldest patients using insulin were dominant in the ‘high utilisation, GP and nurse’ profile. High total healthcare utilisation was not associated with high diabetes-related healthcare utilisation. Conclusions Healthcare utilisation of diabetes patients is heterogeneous. This challenges the development of distinguishable DMPs.

  1. Electron number density profiles derived from radio occultation on the CASSIOPE spacecraft

    DEFF Research Database (Denmark)

    Shume, E. B.; Vergados, P.; Komjathy, A.

    2017-01-01

    good agreement with density profiles estimated from ionosonde data, measured over nearby stations to the latitude and longitude of the RO tangent points, (2) in good agreement with density profiles inferred from GPS RO measured by the Constellation Observing System for Meteorology, Ionosphere......, and Climate (COSMIC), and (3) in general agreement with density profiles estimated using the International Reference Ionosphere (IRI) climatological model. Using both CASSIOPE and COSMIC RO observations, we identify, for the first time, that there exist differences in the characteristics of the electron...

  2. Size and average density spectra of macromolecules obtained from hydrodynamic data.

    Science.gov (United States)

    Pavlov, G M

    2007-02-01

    It is proposed to normalize the Mark-Kuhn-Houwink-Sakurada type of equation relating the hydrodynamic characteristics, such as intrinsic viscosity, velocity sedimentation coefficient and translational diffusion coefficient of linear macromolecules to their molecular masses for the values of linear density M(L) and the statistical segment length A. When the set of data covering virtually all known experimental information is normalized for M(L), it is presented as a size spectrum of linear polymer molecules. Further normalization for the A value reduces all data to two regions: namely the region exhibiting volume interactions and that showing hydrodynamic draining. For chains without intachain excluded volume effects these results may be reproduced using the Yamakawa-Fujii theory of wormlike cylinders. Data analyzed here cover a range of contour lengths of linear chains varying by three orders of magnitude, with the range of statistical segment lengths varying approximately 500 times. The plot of the dependence of [eta]M on M represents the spectrum of average specific volumes occupied by linear and branched macromolecules. Dendrimers and globular proteins for which the volume occupied by the molecule in solution is directly proportional to M have the lowest specific volume. The homologous series of macromolecules in these plots are arranged following their fractal dimensionality.

  3. Sperm fractions obtained following density gradient centrifugation in human ejaculates show differences in sperm DNA longevity

    Institute of Scientific and Technical Information of China (English)

    Jaime Goslvez; Stephen Johnston; Carmen Lpez-Fernndez; Altea Goslbez; Francisca Arroyo; Jose Lus Fernndez; Juan G lvarez

    2014-01-01

    Objective:To investigate the DNA longevity characteristics associated with each resultant fraction following density gradient centrifugation (DGC) in comparison to that of the original neat ejaculated sample. Methods:An aliquot of neat semen (NSS) collected from 7 patients was processed using DGC resulting in 3 fractions;Fraction 1:seminal plasma/40%gradient interface (GI);Fraction 2:40%GI/80%GI;Fraction 3:80%GI/pellet. An aliquot of each fraction and NSS was cryopreserved, thawed and incubated at 37 ℃for 24h;the increase of sperm DNA fragmentation was assessed using the Dyn-Halosperm assay following 0, 3, 6 and 24h of incubation. Results:While there was a significant reduction in the incidence of baseline sperm DNA fragmentation following DGC in Fraction 3, sperm DNA longevity was shown to be higher in the NSS than in any other sub-population following incubation. The highest levels of baseline DNA damage were found in Fractions 1 and 2;these fractions also showed the highest rate DNA fragmentation following incubation, subsequently exhibiting the lowest DNA longevity. Conclusion:1) Unnecessary incubation of spermatozoa prior to artificial insemination or in vitro fertilization, should be avoided, since sperm DNA longevity is significantly reduced after ex vivo sperm handling and 2) Although sperm selection by DCG significantly reduces the baseline levels of SDF of sperm in Fraction 3, sperm DNA longevity in this fraction was ultimately lower following 24 h incubation when compared to sperm recovered from non-centrifuged NSS.

  4. The Stellar Density Profile of the Distant Galactic Halo

    CERN Document Server

    Slater, Colin T; Munn, Jeffrey A; Bell, Eric F; Majewski, Steven R

    2016-01-01

    We use extensive gravity-sensitive DDO 51 photometry over 5100 square degrees, combined with SDSS broadband photometry, to select a catalog of $\\sim 4,000$ giant stars covering a large fraction of the high Galactic latitude sky and reaching out to $\\sim 80$ kpc in the Galactic halo. This sample of bright and unbiased tracers enables us to measure the radial profile and 3D structure of the stellar halo to large distance which had previously only been measured with sparse tracers or small samples. Using population synthesis models to reproduce the observed giant star luminosity function, we find that the halo maintains a $r^{-3.5}$ profile from $30$ to $80$ kpc with no signs of a truncation or sharp break over this range. The radial profile measurement is largely insensitive to individual halo substructure components, but we find that attempting to measure the shape of the halo is overwhelmed by the Sagittarius stream such that no ellipsoidal shape is a satisfactory description in this region. These measurement...

  5. Dependence of the outer density profiles of halos on their mass accretion rate

    Energy Technology Data Exchange (ETDEWEB)

    Diemer, Benedikt; Kravtsov, Andrey V., E-mail: bdiemer@oddjob.uchicago.edu [Department of Astronomy and Astrophysics, The University of Chicago, Chicago, IL 60637 (United States)

    2014-07-01

    We present a systematic study of the density profiles of ΛCDM halos, focusing on the outer regions, 0.1 < r/R {sub vir} < 9. We show that the median and mean profiles of halo samples of a given peak height exhibit significant deviations from the universal analytic profiles discussed previously in the literature, such as the Navarro-Frenk-White and Einasto profiles, at radii r ≳ 0.5R {sub 200m}. In particular, at these radii the logarithmic slope of the median density profiles of massive or rapidly accreting halos steepens more sharply than predicted. The steepest slope of the profiles occurs at r ≈ R {sub 200m}, and its absolute value increases with increasing peak height or mass accretion rate, reaching slopes of –4 and steeper. Importantly, we find that the outermost density profiles at r ≳ R {sub 200m} are remarkably self-similar when radii are rescaled by R {sub 200m}. This self-similarity indicates that radii defined with respect to the mean density are preferred for describing the structure and evolution of the outer profiles. However, the inner density profiles are most self-similar when radii are rescaled by R {sub 200c}. We propose a new fitting formula that describes the median and mean profiles of halo samples selected by their peak height or mass accretion rate with accuracy ≲ 10% at all radii, redshifts, and masses we studied, r ≲ 9R {sub vir}, 0 < z < 6, and M {sub vir} > 1.7 × 10{sup 10} h {sup –1} M {sub ☉}. We discuss observational signatures of the profile features described above and show that the steepening of the outer profile should be detectable in future weak-lensing analyses of massive clusters. Such observations could be used to estimate the mass accretion rate of cluster halos.

  6. Transcriptional profile of fibroblasts obtained from the primary site, lymph node and bone marrow of breast cancer patients

    OpenAIRE

    2014-01-01

    Cancer-associated fibroblasts (CAF) influence tumor development at primary as well as in metastatic sites, but there have been no direct comparisons of the transcriptional profiles of stromal cells from different tumor sites. In this study, we used customized cDNA microarrays to compare the gene expression profile of stromal cells from primary tumor (CAF, n = 4), lymph node metastasis (N+, n = 3) and bone marrow (BM, n = 4) obtained from breast cancer patients. Biological validation was done ...

  7. A method of rapidly obtaining concentration-depth profiles from X-ray diffraction

    Science.gov (United States)

    Wiedemann, K. E.; Unnam, J.

    1985-01-01

    A broadened diffraction peak, or intensity band, is observed in the case diffraction from a nonhomogeneous phase in which the variations in compositions result in a range of lattice spacings. An intriguing aspect regarding the relationship between the X-ray diffraction band and the composition-depth profile is the hypersensitivity of the intensity band to the shape of the profile. A number of investigators have sought to use this sensitivity to construct high-precision profiles. Difficulties encountered are related to complications due to intensity broadening, and prohibitive computational requirements. Simulation techniques have provided the most accurate interpretation of the intensity band. However, the involved calculations have been prohibitively long. The present study discusses a technique which has simple computational requirements and is as accurate and flexible as the simulation techniques.

  8. Derivation of the Fano profile from time-dependent density-functional theory for local thermodynamic equilibrium plasmas

    Science.gov (United States)

    Kiyokawa, Shuji

    2007-04-01

    We give the derivation of the Fano profile (the resonance energy position, the resonance width Γ , and q value) from the time-dependent nonrelativistic density-functional theory (DFT) and propose a scheme for calculating the photoabsorption cross section of hot dense plasmas. As a consequence of this derivation, we show the line profile is obtained as a superposition of Fano and Lorentz profiles when the competition of two optically allowed bound-bound and bound-free transitions occurs. We also show the results of the photoabsorption cross section by applying our scheme to an Fe plasma (density is 7.85g/cm3 , temperature is 100eV ), where the calculation is carried out without numerical divergence for any photon energy. The calculated results are in good agreement with those of Grimaldi.

  9. On the density profile of dark matter substructure in gravitational lens galaxies

    CERN Document Server

    Vegetti, Simona

    2014-01-01

    We consider three extensions of the Navarro, Frenk and White (NFW) profile and investigate the intrinsic degeneracies among the density profile parameters on the gravitational lensing effect of satellite galaxies on highly magnified Einstein rings. In particular, we find that the gravitational imaging technique can be used to exclude specific regions of the considered parameter space, and therefore, models that predict a large number of satellites in those regions. By comparing the lensing degeneracy with the intrinsic density profile degeneracies, we show that theoretical predictions based on fits that are dominated by the density profile at larger radii may significantly over- or underestimate the number of satellites that are detectable with gravitational lensing. Finally, using the previously reported detection of a satellite in the gravitational lens system JVAS B1938+666 as an example, we derive for this detected satellite values of r_max and v_max that are, for each considered profile, consistent withi...

  10. Design of Q-band FMCW reflectometry for electron density profile measurement on the Joint TEXT tokamak

    Science.gov (United States)

    Linghan, Wan; Zhoujun, Yang; Ruobing, Zhou; Xiaoming, Pan; Chi, Zhang; Xianli, Xie; Bowen, Ruan

    2017-02-01

    The Q-band (33-50 GHz) fast sweep frequency modulated continuous wave (FMCW) reflectometry has been recently developed for electron density profile measurement on the Joint TEXT tokamak. It operates in ordinary mode (O-mode) with a 20 μs sweeping period, covering the density range from 1 × 1019 m-3 to 3 × 1019 m-3. On the bench test, a Yttrium Iron Garnet (YIG) filter is used for the dynamic calibration of the voltage controlled oscillator (VCO) to obtain a linear frequency sweep. Besides, the use of a power combiner helps to improve the side-band suppression level of the single side-band modulator (SSBM). The reconstructed density profiles are presented, which demonstrate the capability of the reflectometry.

  11. Endovascular biopsy: Strategy for analyzing gene expression profiles of individual endothelial cells obtained from human vessels✩

    Science.gov (United States)

    Sun, Zhengda; Lawson, Devon A.; Sinclair, Elizabeth; Wang, Chih-Yang; Lai, Ming-Derg; Hetts, Steven W.; Higashida, Randall T.; Dowd, Christopher F.; Halbach, Van V.; Werb, Zena; Su, Hua; Cooke, Daniel L.

    2015-01-01

    Purpose To develop a strategy of achieving targeted collection of endothelial cells (ECs) by endovascular methods and analyzing the gene expression profiles of collected single ECs. Methods and results 134 ECs and 37 leukocytes were collected from four patients' intra-iliac artery endovascular guide wires by fluorescence activated cell sorting (FACS) and analyzed by single-cell quantitative RT-PCR for expression profile of 48 genes. Compared to CD45+ leukocytes, the ECs expressed higher levels (p < 0.05) of EC surface markers used on FACS and other EC related genes. The gene expression profile showed that these isolated ECs fell into two clusters, A and B, that differentially expressed 19 genes related to angiogenesis, inflammation and extracellular matrix remodeling, with cluster B ECs have demonstrating similarities to senescent or aging ECs. Conclusion Combination of endovascular device sampling, FACS and single-cell quantitative RT-PCR is a feasible method for analyzing EC gene expression profile in vascular lesions. PMID:26989654

  12. Dynamics of electron injection and acceleration driven by laser wakefield in tailored density profiles

    Science.gov (United States)

    Lee, P.; Maynard, G.; Audet, T. L.; Cros, B.; Lehe, R.; Vay, J.-L.

    2016-11-01

    The dynamics of electron acceleration driven by laser wakefield is studied in detail using the particle-in-cell code WARP with the objective to generate high-quality electron bunches with narrow energy spread and small emittance, relevant for the electron injector of a multistage accelerator. Simulation results, using experimentally achievable parameters, show that electron bunches with an energy spread of ˜11 % can be obtained by using an ionization-induced injection mechanism in a mm-scale length plasma. By controlling the focusing of a moderate laser power and tailoring the longitudinal plasma density profile, the electron injection beginning and end positions can be adjusted, while the electron energy can be finely tuned in the last acceleration section.

  13. Evolution of density and velocity profiles of matter in large voids

    CERN Document Server

    Tsizh, Maksym

    2016-01-01

    We analyse the evolution of cosmological perturbations which leads to the formation of large voids in the distribution of galaxies. We assume that perturbations are spherical and all components of the Universe - radiation, matter and dark energy - are continuous media with ideal fluid energy-momentum tensors, which interact only gravitationally. Equations of the evolution of perturbations in the comoving to cosmological background reference frame for every component are obtained from equations of conservation and Einstein's ones and are integrated by modified Euler method. Initial conditions are set at the early stage of evolution in the radiation-dominated epoch, when the scale of perturbation is mush larger than the particle horizon. Results show how the profiles of density and velocity of matter in spherical voids with different overdensity shells are formed.

  14. Evolution of density and velocity profiles of matter in large voids

    Science.gov (United States)

    Tsizh, M.; Novosyadlyj, B.

    2016-09-01

    We analyse the evolution of cosmological perturbations which leads to the formation of large voids in the distribution of galaxies. We assume that perturbations are spherical and all components of the Universe - radiation, matter and dark energy - are continuous media with ideal fluid energy-momentum tensors, which interact only gravitationally. Equations of the evolution of perturbations in the comoving to cosmological background reference frame for every component are obtained from equations of conservation and Einstein's ones and are integrated by modified Euler method. Initial conditions are set at the early stage of evolution in the radiation-dominated epoch, when the scale of perturbation is mush larger than the particle horizon. Results show how the profiles of density and velocity of matter in spherical voids with different overdensity shells are formed.

  15. Size distribution and radial density profile of synaptic vesicles by SAXS and light scattering

    Energy Technology Data Exchange (ETDEWEB)

    Castorph, Simon; Salditt, Tim [Institute for X-ray Physics, Goettingen (Germany); Holt, Matthew; Jahn, Reinhard [Max Plank Institute for Biophysical Chemistry, Goettingen (Germany); Sztucki, Michael [European Synchrotron Radiation Facility, Grenoble (France)

    2008-07-01

    Synaptic vesicles are small membraneous organelles within the nerve terminal, encapsulating neurotransmitters by a lipid bilayer. The transport of the neurotransmitter, the fusion at the plasma membrane, and the release of the stored neurotransmitters into the synaptic cleft are since long know as essential step in nerve conduction of the chemical synapse. A detailed structural view of these molecular mechanisms is still lacking, not withstanding the enormous progress in the field during recent years. From measurements and quantitative fitting of small angle X-ray scattering curves and dynamic light scattering the averaged structural properties of synaptic vesicles can be determined. We present SAXS measurements and fits revealing the width of the size distribution function and details of the radial scattering length profile of synaptic vesicles from rat brain. Representative values for the inner and outer radius and the size polydispersity as well as the density and width of the outer protein layer are obtained.

  16. New density profile and structural parameters of the complex stellar system Terzan 5

    CERN Document Server

    Lanzoni, B; Dalessandro, E; Mucciarelli, A; Beccari, G; Miocchi, P; Bellazzini, M; Rich, R M; Origlia, L; Valenti, E; Rood, R T; Ransom, S

    2010-01-01

    Terzan 5 is a globular cluster-like stellar system in the Galactic Bulge which has been recently found to harbor two stellar populations with different iron content and probably different ages (Ferraro et al. 2009). This discovery suggests that Terzan 5 may be the relic of a primordial building block which contributed to the formation of the Galactic Bulge. Here we present a re-determination of the structural parameters (center of gravity, density and surface brightness profiles, total luminosity and mass) of Terzan 5, as obtained from the combination of high-resolution (ESO-MAD and HST ACS-WFC) and wide-field (ESO-WFI) observations. We find that Terzan 5 is significantly less concentrated and more massive than previously thought. Still it has the largest collision rate of any stellar aggregate in the Galaxy. We discuss the impact of these findings on the exceptional population of millisecond pulsars harbored in this stellar system.

  17. Cluster density profiles as a test of modified gravity

    Science.gov (United States)

    Lombriser, Lucas; Schmidt, Fabian; Baldauf, Tobias; Mandelbaum, Rachel; Seljak, Uroš; Smith, Robert E.

    2012-05-01

    We present a new test of gravitational interactions at the r≃(0.2-20)Mpc scale, around the virial radius of dark matter halos measured through cluster-galaxy lensing of maxBCG clusters from the Sloan Digital Sky Survey (SDSS). We employ predictions from self-consistent simulations of f(R) gravity to find an upper bound on the background field amplitude of |fR0|confidence level. As a model-independent assessment of the constraining power of cluster profiles measured through weak gravitational lensing, we also constrain the amplitude F0 of a phenomenological modification based on the profile enhancement induced by f(R) gravity when not including effects from the increased cluster abundance in f(R). In both scenarios, dark-matter-only simulations of the concordance model corresponding to |fR0|=0 and F0=0 are consistent with the lensing measurements, i.e., at the 68% and 95% confidence level, respectively.

  18. Near-exponential surface densities as hydrostatic, nonequilibrium profiles in galaxy discs

    CERN Document Server

    Struck, Curtis

    2016-01-01

    Apparent exponential surface density profiles are nearly universal in galaxy discs across Hubble types, over a wide mass range, and a diversity of gravitational potential forms. Several processes have been found to produce exponential profiles, including the actions of bars and spirals, and clump scattering, with star scattering a common theme in these. Based on reasonable physical constraints, such as minimal entropy gradients, we propose steady state distribution functions for disc stars, applicable over a range of gravitational potentials. The resulting surface density profiles are generally a power-law term times a Sersic-type exponential. Over a modest range of Sersic index values, these profiles are often indistinguishable from Type I exponentials, except at the innermost radii. However, in certain parameter ranges these steady states can appear as broken, Type II or III profiles. The corresponding velocity dispersion profiles are low order power-laws. A chemical potential associated with scattering can...

  19. Botanical origin causes changes in nutritional profile and antioxidant activity of fermented products obtained from honey.

    Science.gov (United States)

    Dezmirean, Graţia I; Mărghitaş, Liviu A; Bobiş, Otilia; Dezmirean, Daniel S; Bonta, Victoriţa; Erler, Silvio

    2012-08-15

    Honey as rich source of enzymatic and nonenzymatic antioxidants serves as health-promoting nutrient in the human body. Here, we present the first time a comparative study of nutritional profiles (e.g., acidities, sugar, organic acid profile, total polyphenolic, flavonoid content) for different unifloral, multifloral honeys and their fermented products, in correlation with their antioxidant activity. Additionally, an optimized method for HPLC separation of organic acids from honey was established. The total phenolic content of honey samples varied widely among the honey types compared to fermented products. High amounts of total flavonoids were quantified in heather honey, followed by raspberry, multifloral, black locust, and linden honey. A positive correlation between the content of polyphenols, flavonoids, and antioxidant activity was observed in honey samples. After fermentation, the flavonoid content of dark honey fermented products decreased significantly. Black locust and linden honeys are more suitable for fermentation because the decrease in antioxidant substances is less pronounced.

  20. Observing the dark matter density profile of isolated galaxies

    CERN Document Server

    Prada, F; Klypin, A; Holtzman, J A; Schlegel, D J; Grebel, E K; Rix, H W; Brinkmann, J; McKay, T A; Csabai, I; Prada, Francisco; Vitvitska, Mayrita; Klypin, Anatoly; Holtzman, Jon A.; Schlegel, David J.; Grebel, Eva K.

    2003-01-01

    Using the Sloan Digital Sky Survey (SDSS), we probe the halo mass distribution by studying the velocities of satellites orbiting isolated galaxies. In a subsample that covers 2500 sq. degrees on the sky, we detect about 3000 satellites with absolute blue magnitudes going down to M_B = -14; most of the satellites have M_B=-16 to -18, comparable to the magnitudes of M32 and the Magellanic Clouds. After a careful, model-independent removal of interlopers, we find that the line-of-sight velocity dispersion of satellites declines with distance to the primary. For an L* galaxy the r.m.s. line-of-sight velocity changes from ~120 km/s at 20 kpc to ~60 km/s at 350 kpc. This decline agrees remarkably well with theoretical expectations, as all modern cosmological models predict that the density of dark matter in the peripheral parts of galaxies declines as rho_DM propto r^{-3}. Thus, for the first time we find direct observational evidence of the density decline predicted by cosmological models; we also note that this r...

  1. Cluster Density Profiles as a Test of Modified Gravity

    CERN Document Server

    Lombriser, Lucas; Baldauf, Tobias; Mandelbaum, Rachel; Seljak, Uros; Smith, Robert E

    2011-01-01

    We present a new test of gravitational interactions at the r\\simeq(0.2-20)Mpc scale, around the virial radius of dark matter halos measured through cluster-galaxy lensing of maxBCG clusters from the Sloan Digital Sky Survey (SDSS). We employ predictions from self-consistent simulations of f(R) gravity to find an upper bound on the background field amplitude of f_R0<3.5x10^-3 at the 1D-marginalized 95% confidence level. We also constrain the amplitude F_0 of a phenomenological fit modeled on the profile enhancement induced by f(R) gravity when not including effects from the increased cluster abundance in f(R). In both scenarios, dark-matter-only simulations of the concordance model corresponding to f_R0=0 and F_0=0 are consistent with the lensing measurements at the 68% confidence level.

  2. The influence of third-order interactions on the density profile of associating hard spheres

    Science.gov (United States)

    Henderson, D.; Sokolowski, S.; Zagorski, R.; Trokhymchuk, A.

    Canonical ensemble Monte Carlo simulations and the non-uniform Percus-Yevick (NPY) equation for the local density are used to study the influence of surface mediated thirdorder interactions on the adsorption of associating hard spheres on a hard wall. A comparison of the NPY density profiles with the computer simulations data indicates that this approximation predicts the fluid structure reasonably well.

  3. High precision measurement of fuel density profiles in nuclear fusion plasmas

    NARCIS (Netherlands)

    Svensson, J.; von Hellermann, M.; Konig, R.

    2002-01-01

    This paper presents a method for deducing fuel density profiles of nuclear fusion plasmas in realtime during an experiment. A Multi Layer Perceptron (MLP) neural network is used to create a mapping between plasma radiation spectra and indirectly deduced hydrogen isotope densities. By combining diffe

  4. Global characteristics of the upper transition height derived from the topside Alouette/ISIS topside sounder electron density profiles, the Formosat-3/COSMIC density profiles and the IRI ion composition model

    Science.gov (United States)

    Truhlik, Vladimir; Triskova, Ludmila; Benson, Robert; Bilitza, Dieter; Chu, Philip; Richards, Phil G.; Wang, Yongli

    The upper transition height (Ht) (the altitude of the transition from heavy atomic ions to light ions or in the simplest form the transition from O+ to H+) is an important parameter, representing the boundary between the ionosphere and the plasmasphere. Ht is very sensitive to various geophysical parameters, like solar and magnetic activity and strongly depends on latitude and local time. There were numerous studies of this parameter in past decades. In spite of these efforts, no model satisfactorily represents this parameter so far. Moreover, surprising evidence of very low transition heights during the last prolonged solar minimum, of a level never obtained before, have been reported. We investigate the upper transition height on the global scale. We made progress in processing large data sets of Ht deduced from the Alouette/ISIS topside sounder and from the Formosat-3/COSMIC vertical electron-density profiles Ne(h) using the theoretical Global Plasma Ionosphere Density (GPID) model (Webb and Essex, 2004) and a revised non-linear function describing the scale height vs. altitude (Titheridge, 1976) to fit the vertical density profiles to the observed profiles and to determine the upper transition height. Since both methods require the plasma temperatures and their gradients as input, these are calculated using the IRI2012 model. Both methods are verified using a large amount of electron and ion density profiles simulated by the FLIP theoretical model and their accuracy is discussed. We compare the results from Alouette/ISIS and Formosat-3/COSMIC and present a global distribution of the calculated Ht and its dependence on geophysical parameters. Finally we compare it with Ht calculated using the IRI ion composition model. Titheridge, J.E., 1976. Ion Transition Heights from Topside Electron-Density Profiles. Planetary and Space Science 24 (3), 229-245. Webb, P.A., Essex, E.A., 2004. A dynamic global model of the plasmasphere. Journal of Atmospheric and Solar

  5. Understanding the core density profile in TCV H-mode plasmas

    CERN Document Server

    Wágner, Dávid; Pitzschke, Andreas; Sauter, Olivier; Weisen, Henri

    2012-01-01

    Results from a database analysis of H-mode electron density profiles on the Tokamak \\`a Configuration Variable (TCV) in stationary conditions show that the logarithmic electron density gradient increases with collisionality. By contrast, usual observations of H-modes showed that the electron density profiles tend to flatten with increasing collisionality. In this work it is reinforced that the role of collisionality alone, depending on the parameter regime, can be rather weak and in these, dominantly electron heated TCV cases, the electron density gradient is tailored by the underlying turbulence regime, which is mostly determined by the ratio of the electron to ion temperature and that of their gradients. Additionally, mostly in ohmic plasmas, the Ware-pinch can significantly contribute to the density peaking. Qualitative agreement between the predicted density peaking by quasi-linear gyrokinetic simulations and the experimental results is found. Quantitative comparison would necessitate ion temperature meas...

  6. Electron density profiles in the background of LF absorption during Forbush-decrease and PSE

    Science.gov (United States)

    Satori, G.

    1989-01-01

    Based on the simulation of different Forbush decrease and particle precipitation effects in the D region, electron density profiles in the mid-latitudes the ionospheric absorption of low frequency (LF) radio waves was determined. The absorption variations at different frequenceis are strongly affected by the shape of the electron density profile. A structure appears which sometimes resembles the letter S (in a sloping form). Both the height (around 70 to 72 km) and the depth of the local minimum in the electron density contribute to the computed absorption changes of various degree at different frequencies. In this way several observed special absorption events can be interpreted.

  7. Effect of Control Blade History, and Axial Coolant Density and Burnup Profiles on BWR Burnup Credit

    Energy Technology Data Exchange (ETDEWEB)

    Marshall, William BJ J [ORNL

    2016-01-01

    A technical basis for peak reactivity boiling water reactor (BWR) burnup credit (BUC) methods was recently generated, and the technical basis for extended BWR BUC is now being developed. In this paper, a number of effects related to extended BWR BUC are analyzed, including three major operational effects in BWRs: the coolant density axial distribution, the use of control blades during operation, and the axial burnup profile. Specifically, uniform axial moderator density profiles are analyzed and compared to previous results and an additional temporal fidelity study combing moderator density profiles for three different fuel assemblies is presented. Realistic control blade histories and cask criticality results are compared to previously generated constructed control blade histories. Finally, a preliminary study of the axial burnup profile is provided.

  8. Modification of SOL profiles and fluctuations with line-average density and divertor flux expansion in TCV

    DEFF Research Database (Denmark)

    Vianello, N.; Tsui, C.; Theiler, C.

    2017-01-01

    that this modification does not influence neither the detachment density threshold, nor the development of a flat SOL density profile which instead depends strongly on the increase of the core line average density. The modification of the SOL upstream profile, with the appearance of what is generally called a density...

  9. Development of the W-band density profile and fluctuation reflectometer on EAST

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Y.M.; Gao, X., E-mail: xgao@ipp.ac.cn; Ling, B.L.; Zhang, S.B.; Zhang, T.; Han, X.; Liu, S.C.; Liu, Z.X.; Liu, Y.; Ti, A.

    2013-11-15

    Highlights: • A X-mode W-band reflectometer is designed and installed on Experimental Advanced Superconducting Tokamak (EAST) for the first time. • Both density profile and fluctuations can be measured by the newly developed reflectometer. • The core density profile has been measured in high magnetic field condition together with V-band reflectometer. • Sawtooth precursor has been measured by fluctuation reflectometer in the low magnetic field condition. -- Abstract: A X-mode polarized W-band reflectometer for plasma density profile and fluctuation measurement is designed and installed on EAST. In measuring the density profile, a voltage controlled oscillator (VCO) is used as the source, allowing a high temporal resolution measurement. The density profile in a plasma with high magnetic field (3.0 T) has been measured by combination of V- and W-band reflectometers. For fluctuation measurements, a frequency synthesizer is used instead of the VCO as a microwave source. The core density fluctuations during sawtooth activity are measured and analyzed.

  10. Reaching Higher Densities for Laboratory White Dwarf Photospheres to Measure Spectroscopic Line Profiles

    CERN Document Server

    Falcon, Ross E; Gomez, T A; Schaeuble, M; Nagayama, T; Montgomery, M H; Winget, D E; Rochau, G A

    2016-01-01

    As part of our laboratory investigation of the theoretical line profiles used in white dwarf atmosphere models, we extend the electron-density ($n_{\\rm e}$) range measured by our experiments to higher densities (up to $n_{e}\\sim80\\times10^{16}$ cm$^{-3}$). Whereas inferred parameters using the hydrogen-$\\beta$ spectral line agree among different line-shape models for $n_{\\rm e}\\lesssim30\\times10^{16}$ cm$^{-3}$, we now see divergence between models. These are densities beyond the range previously benchmarked in the laboratory, meaning theoretical profiles in this regime have not been fully validated. Experimentally exploring these higher densities enables us to test and constrain different line-profile models, as the differences in their relative H-Balmer line shapes are more pronounced at such conditions. These experiments also aid in our study of occupation probabilities because we can measure these from relative line strengths.

  11. Theory for planetary exospheres: II. Radiation pressure effect on exospheric density profiles

    CERN Document Server

    Beth, Arnaud; Toublanc, Dominique; Dandouras, Iannis; Mazelle, Christian

    2015-01-01

    The planetary exospheres are poorly known in their outer parts, since the neutral densities are low compared with the instruments detection capabilities. The exospheric models are thus often the main source of information at such high altitudes. We present a new way to take into account analytically the additional effect of the radiation pressure on planetary exospheres. In a series of papers, we present with an Hamiltonian approach the effect of the radiation pressure on dynamical trajectories, density profiles and escaping thermal flux. Our work is a generalization of the study by Bishop and Chamberlain (1989). In this second part of our work, we present here the density profiles of atomic Hydrogen in planetary exospheres subject to the radiation pressure. We first provide the altitude profiles of ballistic particles (the dominant exospheric population in most cases), which exhibit strong asymmetries that explain the known geotail phenomenon at Earth. The radiation pressure strongly enhances the densities c...

  12. Self-similarity and universality of void density profiles in simulation and SDSS data

    CERN Document Server

    Nadathur, S; Diego, J M; Iliev, I T; Gottlöber, S; Watson, W A; Yepes, G

    2014-01-01

    The stacked density profile of cosmic voids in the galaxy distribution provides an important tool for the use of voids for precision cosmology. We study the density profiles of voids identified using the ZOBOV watershed transform algorithm in realistic mock luminous red galaxy (LRG) catalogues from the Jubilee simulation, as well as in void catalogues constructed from the SDSS LRG and Main Galaxy samples. We compare different methods for reconstructing density profiles scaled by the void radius and show that the most commonly used method based on counts in shells and simple averaging is statistically flawed as it underestimates the density in void interiors. We provide two alternative methods that do not suffer from this effect; one based on Voronoi tessellations is also easily able to account from artefacts due to finite survey boundaries and so is more suitable when comparing simulation data to observation. Using this method we show that voids in simulation are exactly self-similar, meaning that their avera...

  13. A Southern Indian Ocean database of hydrographic profiles obtained with instrumented elephant seals.

    Science.gov (United States)

    Roquet, Fabien; Williams, Guy; Hindell, Mark A; Harcourt, Rob; McMahon, Clive; Guinet, Christophe; Charrassin, Jean-Benoit; Reverdin, Gilles; Boehme, Lars; Lovell, Phil; Fedak, Mike

    2014-01-01

    The instrumentation of southern elephant seals with satellite-linked CTD tags has offered unique temporal and spatial coverage of the Southern Indian Ocean since 2004. This includes extensive data from the Antarctic continental slope and shelf regions during the winter months, which is outside the conventional areas of Argo autonomous floats and ship-based studies. This landmark dataset of around 75,000 temperature and salinity profiles from 20-140 °E, concentrated on the sector between the Kerguelen Islands and Prydz Bay, continues to grow through the coordinated efforts of French and Australian marine research teams. The seal data are quality controlled and calibrated using delayed-mode techniques involving comparisons with other existing profiles as well as cross-comparisons similar to established protocols within the Argo community, with a resulting accuracy of ±0.03 °C in temperature and ±0.05 in salinity or better. The data offer invaluable new insights into the water masses, oceanographic processes and provides a vital tool for oceanographers seeking to advance our understanding of this key component of the global ocean climate.

  14. Magnetic resonance metabolic profiling of breast cancer tissue obtained with core needle biopsy for predicting pathologic response to neoadjuvant chemotherapy.

    Directory of Open Access Journals (Sweden)

    Ji Soo Choi

    Full Text Available The purpose of this study was to determine whether metabolic profiling of core needle biopsy (CNB samples using high-resolution magic angle spinning (HR-MAS magnetic resonance spectroscopy (MRS could be used for predicting pathologic response to neoadjuvant chemotherapy (NAC in patients with locally advanced breast cancer. After institutional review board approval and informed consent were obtained, CNB tissue samples were collected from 37 malignant lesions in 37 patients before NAC treatment. The metabolic profiling of CNB samples were performed by HR-MAS MRS. Metabolic profiles were compared according to pathologic response to NAC using the Mann-Whitney test. Multivariate analysis was performed with orthogonal projections to latent structure-discriminant analysis (OPLS-DA. Various metabolites including choline-containing compounds were identified and quantified by HR-MAS MRS in all 37 breast cancer tissue samples obtained by CNB. In univariate analysis, the metabolite concentrations and metabolic ratios of CNB samples obtained with HR-MAS MRS were not significantly different between different pathologic response groups. However, there was a trend of lower levels of phosphocholine/creatine ratio and choline-containing metabolite concentrations in the pathologic complete response group compared to the non-pathologic complete response group. In multivariate analysis, the OPLS-DA models built with HR-MAS MR metabolic profiles showed visible discrimination between the pathologic response groups. This study showed OPLS-DA multivariate analysis using metabolic profiles of pretreatment CNB samples assessed by HR- MAS MRS may be used to predict pathologic response before NAC, although we did not identify the metabolite showing statistical significance in univariate analysis. Therefore, our preliminary results raise the necessity of further study on HR-MAS MR metabolic profiling of CNB samples for a large number of cancers.

  15. Evolution of density and velocity profiles of dark matter and dark energy in spherical voids

    Science.gov (United States)

    Novosyadlyj, Bohdan; Tsizh, Maksym; Kulinich, Yurij

    2017-02-01

    We analyse the evolution of cosmological perturbations which leads to the formation of large isolated voids in the Universe. We assume that initial perturbations are spherical and all components of the Universe (radiation, matter and dark energy) are continuous media with ideal fluid energy-momentum tensors, which interact only gravitationally. Equations of the evolution of perturbations for every component in the comoving to cosmological background reference frame are obtained from equations of energy and momentum conservation and Einstein's ones and are integrated numerically. Initial conditions are set at the early stage of evolution in the radiation-dominated epoch, when the scale of perturbation is much larger than the particle horizon. Results show how the profiles of density and velocity of matter and dark energy are formed and how they depend on parameters of dark energy and initial conditions. In particular, it is shown that final matter density and velocity amplitudes change within range ˜4-7 per cent when the value of equation-of-state parameter of dark energy w vary in the range from -0.8 to -1.2, and change within ˜1 per cent only when the value of effective sound speed of dark energy vary over all allowable range of its values.

  16. The effect of baryons on the inner density profiles of rich clusters

    CERN Document Server

    Schaller, Matthieu; Bower, Richard G; Theuns, Tom; Trayford, James; Crain, Robert A; Furlong, Michelle; Schaye, Joop; Vecchia, Claudio Dalla; McCarthy, I G

    2014-01-01

    We use the "Evolution and assembly of galaxies and their environment" (EAGLE) cosmological simulation to investigate the effect of baryons on the density profiles of rich galaxy clusters. We focus on the six most massive EAGLE clusters ($M_{200} > 10^{14}M_\\odot$) which can be compared with a recent analysis of seven real clusters by Newman et al. The central brightest cluster galaxies (BCGs) in EAGLE have steep stellar density profiles, $\\rho_*(r) \\propto r^{-3}$. Stars dominate the mass density for $r < 10~{\\rm kpc}$, and, as a result, the total mass density profiles are steeper than the Navarro-Frenk-White (NFW) profile. However, the dark matter halo itself closely follows the NFW form at all resolved radii ($r\\gtrsim3.0~{\\rm kpc}$). The \\eagle BCGs have similar surface brightness and line-of-sight velocity dispersion profiles as the BCGs observed by Newmanet al. The central slopes of the total mass profiles are also consistent with the observed clusters. However, after subtracting the contribution of t...

  17. Determination of the vertical electron-density profile in ionospheric tomography: experimental results

    Directory of Open Access Journals (Sweden)

    C. N. Mitchell

    Full Text Available The reconstruction of the vertical electron-density profile is a fundamental problem in ionospheric tomography. Lack of near-horizontal ray paths limits the information available on the vertical profile, so that the resultant image of electron density is biased in a horizontal sense. The vertical profile is of great importance as it affects the authenticity of the entire tomographic image. A new method is described whereby the vertical profile is selected using relative total-electron-content measurements. The new reconstruction process has been developed from modelling studies. A range of background ionospheres, representing many possible peak heights, scale heights and electron densities are formed from a Chapman profile on the bottomside with a range of topside profiles. The iterative reconstruction process is performed on all of these background ionospheres and a numerical selection criterion employed to select the final image. The resulting tomographic images show excellent agreement in electron density when compared with independent verification provided by the EISCAT radar.

  18. Density profiles of dark matter halos in an improved Secondary Infall model

    CERN Document Server

    Del Popolo, A; Recami, E; Spedicato, E

    2000-01-01

    In this paper we calculate the density profiles of virialized halos both in the case of structure evolving hierarchically from a scale-free Gaussian delta-field having a power spectrum P(k)=A k^n in a Omega=1 Universe and in the case of the CDM model, by using a modified version of Hoffman & Shaham's (1985) (hereafter HS) and Hoffman's (1988) model. We suppose that the initial density contrast profile around local maxima is given by the mean peak profile introduced by Bardeen et al. (1986) (hereafter BBKS), and is not just proportional to the two-point correlation function, as assumed by HS. We show that the density profiles, both for scale-free Universes and the CDM model, are not power-laws but have a logarithmic slope that increases from the inner halo to its outer parts. Both scale-free, for n >=-1, and CDM density profiles are well approximated by Navarro et al. (1995, 1996, 1997) profile. The radius a, at which the slope alpha=-2, is a function of the mass of the halo and in the scale-free models al...

  19. Seasonal Variations In Density Profiles And Densification Process At Mts. Logan And Wrangell

    Science.gov (United States)

    Kanamori, S.; Shiraiwa, T.; Goto-Azuma, K.; Benson, C. S.; Naruse, R.

    2004-12-01

    Detailed density measurements were carried out for ice cores which were drilled at Mt. Logan (60° 35'20"N, 140° 36'15"W; 4135m a.s.l.; Shiraiwa et al., 2003) and Mt. Wrangell (62° 00'N, 140° 03'W; 4100m a.s.l.; Shiraiwa et al., 2004). The detailed density profiles show periodic fluctuations which seem to indicate seasonal cycles. In Mt. Logan, the number of annual layers which are estimated from the density profile agrees well with that estimated from the oxygen isotope data (Goto-Azuma et al., 2003) and the age of the ice core estimated from tritium peaks. On the other hand, in Mt. Wrangell, the number of annual layers from the density profile is quite different from that of the hydrogen isotope profile. The accumulation time series reconstructed from the density profile in Mt. Wrangell shows significant correlations with precipitation data of weather stations that locate near Mt. Wrangell. Accumulation rate and mean annual temperature at both sites are estimated to be almost the same (Benson & Motyka, 1978; Shiraiwa et al., 2003; Goto-Azuma et al., 2003; Shiraiwa et al., 2004). However, their firn/ice transition depths (Mt. Logan: 50m, Mt. Wrangell: 90m) are considerably different. This difference cannot be explained only from the difference in initial densities. Densification rate in Mt. Logan is higher than in Mt. Wrangell, i.e. compactive viscosity coefficient calculated from depth-density profile in Mt. Wrangell is more than double of the value in Mt. Logan.

  20. Transcriptional profiling of degraded RNA in cryopreserved and fixed tissue samples obtained at autopsy

    Directory of Open Access Journals (Sweden)

    Alhasan Samir

    2006-12-01

    Full Text Available Abstract Background Traditional multiplexed gene expression methods require well preserved, intact RNA. Such specimens are difficult to acquire in clinical practice where formalin fixation is the standard procedure for processing tissue. Even when special handling methods are used to obtain frozen tissue, there may be RNA degradation; for example autopsy samples where degradation occurs both pre-mortem and during the interval between death and cryopreservation. Although specimens with partially degraded RNA can be analyzed by qRT-PCR, these analyses can only be done individually or at low levels of multiplexing and are laborious and expensive to run for large numbers of RNA targets. Methods We evaluated the ability of the cDNA-mediated Annealing, Selection, extension, and Ligation (DASL assay to provide highly multiplexed analyses of cryopreserved and formalin fixed, paraffin embedded (FFPE tissues obtained at autopsy. Each assay provides data on 1536 targets, and can be performed on specimens with RNA fragments as small as 60 bp. Results The DASL performed accurately and consistently with cryopreserved RNA obtained at autopsy as well as with RNA extracted from formalin-fixed paraffin embedded tissue that had a cryopreserved mirror image specimen with high quality RNA. In FFPE tissue where the cryopreserved mirror image specimen was of low quality the assay performed reproducibly on some but not all specimens. Conclusion The DASL assay provides reproducible results from cryopreserved specimens and many FFPE specimens obtained at autopsy. Gene expression analyses of these specimens may be especially valuable for the study of non-cancer endpoints, where surgical specimens are rarely available.

  1. Earth-mass haloes and the emergence of NFW density profiles

    CERN Document Server

    Angulo, Raul E; Ludlow, Aaron; Bonoli, Silvia

    2016-01-01

    We report results from simulations of neutralino dark matter ($\\chi$DM) haloes. We follow them from their emergence at one earth mass to a final mass of a few percent solar. We show that the density profiles of the first haloes are well described by a $\\sim r^{-1.5}$ power-law. As haloes grow in mass, their density profiles evolve significantly. In the central regions, they become shallower and reach on average $\\sim r^{-1}$, the asymptotic form of an NFW profile. However, the profile of individual haloes can show non-monotonic density slopes, and be shallower than $-1$ in some cases. We investigate the transformation of cuspy power-law profiles using a series of non-cosmological simulations of equal-mass mergers. Contrary to previous findings, we observe that temporal variations in the gravitational potential caused by mergers lead to a shallowing of the inner profile, an effect which is stronger for shallower initial profiles and for mergers that involve a higher number of systems. Depending on the merger d...

  2. Limits on the power-law mass and luminosity density profiles of elliptical galaxies from gravitational lensing systems

    CERN Document Server

    Cao, Shuo; Yao, Meng; Zhu, Zong-Hong

    2016-01-01

    We use 118 strong gravitational lenses observed by the SLACS, BELLS, LSD and SL2S surveys to constrain the total mass profile and the profile of luminosity density of stars (light-tracers) in elliptical galaxies up to redshift $z \\sim 1$. Assuming power-law density profiles for the total mass density, $\\rho=\\rho_0(r/r_0)^{-\\alpha}$, and luminosity density, $\

  3. Breast cancer: determining the genetic profile from ultrasound-guided percutaneous biopsy specimens obtained during the diagnostic workups.

    Science.gov (United States)

    López Ruiz, J A; Zabalza Estévez, I; Mieza Arana, J A

    2016-01-01

    To evaluate the possibility of determining the genetic profile of primary malignant tumors of the breast from specimens obtained by ultrasound-guided percutaneous biopsies during the diagnostic imaging workup. This is a retrospective study in 13 consecutive patients diagnosed with invasive breast cancer by B-mode ultrasound-guided 12 G core needle biopsy. After clinical indication, the pathologist decided whether the paraffin block specimens seemed suitable (on the basis of tumor size, validity of the sample, and percentage of tumor cells) before sending them for genetic analysis with the MammaPrint® platform. The size of the tumors on ultrasound ranged from 0.6cm to 5cm. In 11 patients the preserved specimen was considered valid and suitable for use in determining the genetic profile. In 1 patient (with a 1cm tumor) the pathologist decided that it was necessary to repeat the core biopsy to obtain additional samples. In 1 patient (with a 5cm tumor) the specimen was not considered valid by the genetic laboratory. The percentage of tumor cells in the samples ranged from 60% to 70%. In 11/13 cases (84.62%) it was possible to do the genetic analysis on the previously diagnosed samples. In most cases, regardless of tumor size, it is possible to obtain the genetic profile from tissue specimens obtained with ultrasound-guided 12 G core biopsy preserved in paraffin blocks. Copyright © 2015 SERAM. Published by Elsevier España, S.L.U. All rights reserved.

  4. Global tropospheric NO2 profiles obtained from a cloud-slicing technique applied to the Aura OMI observations

    Science.gov (United States)

    Choi, S.; Joiner, J.; Lamsal, L. N.; Marchenko, S. V.; Krotkov, N. A.

    2016-12-01

    Nitrogen dioxide (NO2) is an important trace species in the troposphere; it has adverse human health effects and also contributes to the formation of tropospheric ozone, a criteria pollutant and climate agent. We derive tropospheric NO2 volume mixing ratio (VMR) profiles by applying a cloud slicing technique to data from the Ozone Monitoring Instrument (OMI) on the Aura satellite. In the cloud-slicing approach, the slope of the above-cloud NO2 column versus the cloud scene pressure is proportional to the NO2 VMR. We apply this technique to OMI O2-O2 cloud scene pressures and above-cloud NO2 vertical column densities from a differential optical absorption spectroscopy (DOAS) algorithm. We derived a global seasonal climatology of tropospheric NO2 VMR profiles in cloudy conditions and compare the results with aircraft profiles measured during the NASA Intercontinental Chemical Transport Experiment Phase B (INTEX-B) campaign in 2006. An analysis of our cloud slicing NO2 profiles indicates signatures of uplifted and transported anthropogenic NOx in the middle troposphere as well as lightning-generated NOx in the upper troposphere. We expect that this technique can be applied to future geostationary missions including the NASA Earth Ventures Instrument (EVI) 1 selected mission Tropospheric Emissions: Monitoring of Pollution (TEMPO) over North America, the Korean Geostationary Environment Monitoring Spectrometer (GEMS) over the Asia-Pacific region, and the European Space Agency (ESA) Sentinel-4 over Europe.

  5. Obtaining Highly Excited Eigenstates of Many-Body Localized Hamiltonians by the Density Matrix Renormalization Group Approach.

    Science.gov (United States)

    Khemani, Vedika; Pollmann, Frank; Sondhi, S L

    2016-06-17

    The eigenstates of many-body localized (MBL) Hamiltonians exhibit low entanglement. We adapt the highly successful density-matrix renormalization group method, which is usually used to find modestly entangled ground states of local Hamiltonians, to find individual highly excited eigenstates of MBL Hamiltonians. The adaptation builds on the distinctive spatial structure of such eigenstates. We benchmark our method against the well-studied random field Heisenberg model in one dimension. At moderate to large disorder, the method successfully obtains excited eigenstates with high accuracy, thereby enabling a study of MBL systems at much larger system sizes than those accessible to exact-diagonalization methods.

  6. Real-time control of the plasma density profile on ASDEX upgrade

    Energy Technology Data Exchange (ETDEWEB)

    Mlynek, Alexander

    2010-07-20

    The tokamak concept currently is the most promising approach to future power generation by controlled thermonuclear fusion. The spatial distribution of the particle density in the toroidally confined fusion plasma is of particular importance. This thesis work therefore focuses on the question as to what extent the shape of the density profile can be actively controlled by a feedback loop in the fusion experiment ASDEX Upgrade. There are basically two essential requirements for such feedback control of the density profile, which has been experimentally demonstrated within the scope of this thesis work: On the one hand, for this purpose the density profile must be continuously calculated under real-time constraints during a plasma discharge. The calculation of the density profile is based on the measurements of a sub-millimeter interferometer, which provides the line-integrated electron density along 5 chords through the plasma. Interferometric density measurements can suffer from counting errors by integer multiples of 2{pi} when detecting the phase difference between a probing and a reference beam. As such measurement errors have severe impact on the reconstructed density profile, one major part of this work consists in the development of new readout electronics for the interferometer, which allows for detection of such measurement errors in real-time with high reliability. A further part of this work is the design of a computer algorithm which reconstructs the spatial distribution of the plasma density from the line-integrated measurements. This algorithm has to be implemented on a computer which communicates the measured data to other computers in real-time, especially to the tokamak control system. On the other hand, a second fundamental requirement for the successful implementation of a feedback controller is the identification of at least one actuator which enables a modification of the density profile. Here, electron cyclotron resonance heating (ECRH) has

  7. Profile analysis of hepatic porcine and murine brain tissue slices obtained with a vibratome.

    Science.gov (United States)

    Mattei, G; Cristiani, I; Magliaro, C; Ahluwalia, A

    2015-01-01

    This study is aimed at characterizing soft tissue slices using a vibratome. In particular, the effect of two sectioning parameters (i.e., step size and sectioning speed) on resultant slice thickness was investigated for fresh porcine liver as well as for paraformaldehyde-fixed (PFA-fixed) and fresh murine brain. A simple framework for embedding, sectioning and imaging the slices was established to derive their thickness, which was evaluated through a purposely developed graphical user interface. Sectioning speed and step size had little effect on the thickness of fresh liver slices. Conversely, the thickness of PFA-fixed murine brain slices was found to be dependent on the step size, but not on the sectioning speed. In view of these results, fresh brain tissue was sliced varying the step size only, which was found to have a significant effect on resultant slice thickness. Although precision-cut slices (i.e., with regular thickness) were obtained for all the tissues, slice accuracy (defined as the match between the nominal step size chosen and the actual slice thickness obtained) was found to increase with tissue stiffness from fresh liver to PFA-fixed brain. This quantitative investigation can be very helpful for establishing the most suitable slicing setup for a given tissue.

  8. Modifications of plasma density profile and thrust by neutral injection in a helicon plasma thruster

    Science.gov (United States)

    Takahashi, Kazunori; Takao, Yoshinori; Ando, Akira

    2016-11-01

    Argon propellant is introduced from the upstream and downstream sides of a high power helicon plasma thruster. The plasma density profile and the imparted thrust are measured for various upstream and downstream argon flow rates, where the total gas flow rate of 70 sccm and the resultant vacuum chamber pressure of 0.2 mTorr are maintained. It is observed that the imparted thrust increases with an increase in the downstream gas flow rate; simultaneously an upstream-peaking profile of the plasma density observed for the upstream gas injection becomes uniform for the downstream gas injection. The difference in the thrust between the upstream and downstream gas injections is enhanced by increasing the rf power. The observed density profiles are qualitatively consistent with theoretical predictions taking a neutral depletion effect into account.

  9. Near-exponential surface densities as hydrostatic, non-equilibrium profiles in galaxy discs

    Science.gov (United States)

    Struck, Curtis; Elmegreen, Bruce G.

    2017-01-01

    Apparent exponential surface density profiles are nearly universal in galaxy discs across Hubble types, over a wide mass range, and a diversity of gravitational potential forms. Several processes have been found to produce exponential profiles, including the actions of bars and spirals, and clump scattering, with star scattering a common theme in these. Based on reasonable physical constraints, such as minimal entropy gradients, we propose steady-state distribution functions for disc stars, applicable over a range of gravitational potentials. The resulting surface density profiles are generally a power-law term times a Sérsic-type exponential. Over a modest range of Sérsic index values, these profiles are often indistinguishable from Type I exponentials, except at the innermost radii. However, in certain parameter ranges, these steady states can appear as broken, Type II or III profiles. The corresponding velocity dispersion profiles are low-order power laws. A chemical potential associated with scattering can help understand the effects of long-range scattering. The steady profiles are found to persist through constant velocity expansions or contractions in evolving discs. The proposed distributions and profiles are simple and solve the stellar hydrodynamic equations. They may be especially relevant to thick discs that have settled to a steady form via scattering.

  10. Nonsingular density profiles of dark matter halos and Strong gravitational lensing

    CERN Document Server

    Chen, D M

    2005-01-01

    We use the statistics of strong gravitational lenses to investigate whether the mass profiles with a flat density core are supported. The probability for lensing by halos modeled by nonsingular truncated isothermal sphere (NTIS) with image separations greater than a certain value (ranges from zero to ten arcseconds) is calculated. NTIS is an analytical model for the postcollapse equilibrium structure of virialized objects derived by Shapiro, Iliev & Raga (1999). This profile has a soft core and matches quite well with the mass profiles of dark matter dominated dwarf galaxies deduced from their observed rotation curves. It also agrees well with NFW (Navarro, Frenk & White) at all radii outside of a few NTIS core radii. Unfortunately, compared the results with those for singular lensing halos (NFW and SIS+NFW) and strong lensing observations, the probabilities for lensing by NTIS halos are far too low. While this result is valid for any other nonsingular density profiles (with a large core radius), we c...

  11. Mode I Critical Stress Intensity Factor of Medium - Density Fiberboard Obtained by Single-Edge - Notched Bending Test

    Directory of Open Access Journals (Sweden)

    Hiroshi Yoshihara

    2014-06-01

    Full Text Available The Mode I critical stress intensity factor (KIc obtained by single-edge-notched bending (SENB tests of medium-density fiberboard (MDF was experimentally analyzed. In the SENB test, the critical load for crack propagation (Pc was determined from the relationship between load/loading-line displacement and load/crack opening displacement (COD. A double cantilever beam (DCB test was also conducted and the results were compared with those of SENB tests. The value of Mode I critical stress intensity factor was obtained by introducing an additional crack length, when the crack length ranged from 0.5 to 0.7 times the depth of the specimen. This range coincided well with that used to derive the appropriate KIc value in the single-edge-notched tension (SENT test, which was conducted using the specimens with a similar confi guration cut from the MDF panel used in this study.

  12. Limits on the power-law mass and luminosity density profiles of elliptical galaxies from gravitational lensing systems

    Science.gov (United States)

    Cao, Shuo; Biesiada, Marek; Yao, Meng; Zhu, Zong-Hong

    2016-09-01

    We use 118 strong gravitational lenses observed by the SLACS, BOSS emission-line lens survey (BELLS), LSD and SL2S surveys to constrain the total mass profile and the profile of luminosity density of stars (light tracers) in elliptical galaxies up to redshift z ˜ 1. Assuming power-law density profiles for the total mass density, ρ = ρ0(r/r0)-α, and luminosity density, ν = ν0(r/r0)-δ, we investigate the power-law index and its first derivative with respect to the redshift. Using Monte Carlo simulations of the posterior likelihood taking the Planck's best-fitting cosmology as a prior, we find γ = 2.132 ± 0.055 with a mild trend ∂γ/∂zl = -0.067 ± 0.119 when α = δ = γ, suggesting that the total density profile of massive galaxies could have become slightly steeper over cosmic time. Furthermore, similar analyses performed on sub-samples defined by different lens redshifts and velocity dispersions indicate the need of treating low-, intermediate- and high-mass galaxies separately. Allowing δ to be a free parameter, we obtain α = 2.070 ± 0.031, ∂α/∂zl = -0.121 ± 0.078 and δ = 2.710 ± 0.143. The model in which mass traces light is rejected at >95 per cent confidence, and our analysis robustly indicates the presence of dark matter in the form of a mass component that is differently spatially extended than the light. In this case, intermediate-mass elliptical galaxies (200 km s-1 <σap ≤ 300 km s-1) show the best consistency with the singular isothermal sphere as an effective model of galactic lenses.

  13. A Comparison of Foliage Profiles in the Sierra National Forest Obtained with a Full-Waveform Under-Canopy EVI Lidar System with the Foliage Profiles Obtained with an Airborne Full-Waveform LVIS Lidar System

    Science.gov (United States)

    Zhao, Feng; Yang, Xiaoyuan; Strahler, Alan H.; Schaaf, Crystal L.; Yao, Tian; Wang, Zhuosen; Roman, Miguel O.; Woodcock, Curtis E.; Ni-Meister, Wenge; Jupp, David L. B.; Lovell, Jenny L.; Culvenor, Darius S.; Newnham, Glenn J.; Tang, Hao; Dubayah, Ralph O.

    2013-01-01

    Foliage profiles retrieved froma scanning, terrestrial, near-infrared (1064 nm), full-waveformlidar, the Echidna Validation Instrument (EVI), agree well with those obtained from an airborne, near-infrared, full-waveform, large footprint lidar, the Lidar Vegetation Imaging Sensor (LVIS). We conducted trials at 5 plots within a conifer stand at Sierra National Forest in August, 2008. Foliage profiles retrieved from these two lidar systems are closely correlated (e.g., r = 0.987 at 100 mhorizontal distances) at large spatial coverage while they differ significantly at small spatial coverage, indicating the apparent scanning perspective effect on foliage profile retrievals. Alsowe noted the obvious effects of local topography on foliage profile retrievals, particularly on the topmost height retrievals. With a fine spatial resolution and a small beam size, terrestrial lidar systems complement the strengths of the airborne lidars by making a detailed characterization of the crowns from a small field site, and thereby serving as a validation tool and providing localized tuning information for future airborne and spaceborne lidar missions.

  14. THE DENSITY PROFILES OF MASSIVE, RELAXED GALAXY CLUSTERS. I. THE TOTAL DENSITY OVER THREE DECADES IN RADIUS

    Energy Technology Data Exchange (ETDEWEB)

    Newman, Andrew B.; Ellis, Richard S. [Cahill Center for Astronomy and Astrophysics, California Institute of Technology, MS 249-17, Pasadena, CA 91125 (United States); Treu, Tommaso; Sand, David J. [Department of Physics, University of California, Santa Barbara, CA 93106 (United States); Nipoti, Carlo [Astronomy Department, University of Bologna, via Ranzani 1, I-40127 Bologna (Italy); Richard, Johan [CRAL, Observatorie de Lyon, Universite Lyon 1, 9 Avenue Ch. Andre, F-69561 Saint Genis Laval Cedex (France); Jullo, Eric, E-mail: anewman@astro.caltech.edu [Laboratoire d' Astrophysique de Marseille, Universite d' Aix-Marseille and CNRS, UMR7326, 38 rue F. Joliot-Curie, F-13388 Marseille Cedex 13 (France)

    2013-03-01

    Clusters of galaxies are excellent locations to probe the distribution of baryons and dark matter (DM) over a wide range of scales. We study a sample of seven massive (M {sub 200} = 0.4-2 Multiplication-Sign 10{sup 15} M {sub Sun }), relaxed galaxy clusters with centrally located brightest cluster galaxies (BCGs) at z = 0.2-0.3. Using the observational tools of strong and weak gravitational lensing, combined with resolved stellar kinematics within the BCG, we measure the total radial density profile, comprising both dark and baryonic matter, over scales of {approx_equal} 3-3000 kpc. We present Keck spectroscopy yielding seven new spectroscopic redshifts of multiply imaged sources and extended stellar velocity dispersion profiles of the BCGs. Lensing-derived mass profiles typically agree with independent X-ray estimates within {approx_equal} 15%, suggesting that departures from hydrostatic equilibrium are small and that the clusters in our sample (except A383) are not strongly elongated or compressed along the line of sight. The inner logarithmic slope {gamma}{sub tot} of the total density profile measured over r/r {sub 200} = 0.003-0.03, where {rho}{sub tot}{proportional_to}r{sup -{gamma}{sub t}{sub o}{sub t}}, is found to be nearly universal, with a mean ({gamma}{sub tot}) = 1.16 {+-} 0.05(random){sup +0.05} {sub -0.07} (systematic) and an intrinsic scatter {sigma}{sub {gamma}} < 0.13 (68% confidence). This is further supported by the very homogeneous shape of the observed velocity dispersion profiles, which are mutually consistent after a simple scaling. Remarkably, this slope agrees closely with high-resolution numerical simulations that contain only DM, despite the significant contribution of stellar mass on the scales we probe. The Navarro-Frenk-White profile characteristic of collisionless cold DM is a better description of the total mass density at radii {approx}> 5-10 kpc than that of DM alone. Hydrodynamical simulations that include baryons, cooling, and

  15. Neutrals density profiles in EXTRAP-T2R based on Monte Carlo simulations

    Energy Technology Data Exchange (ETDEWEB)

    Cecconello, M

    2002-07-01

    The role of neutral particles in fusion plasmas is very important affecting several aspects of the discharge properties. In particular the neutrals affect the particle and energy balance, the plasma confinement properties, the density profile, the particle and energy fluxes at the wall and the wall erosion. In addition, highly energetic neutrals are used as a diagnostic of the plasma ion temperature. This report describes MCNC a Monte Carlo code used in EXTRAP T2R for the calculation of the neutrals density profile of hydrogen plasma.

  16. Interplay between density profile and zonal flows in drift kinetic simulations of slab ITG turbulence

    Energy Technology Data Exchange (ETDEWEB)

    Sarazin, Y.; Garbet, X.; Grandgirard, V.; Ghendrih, Ph. [Association Euratom-CEA Cadarache (DSM/DRFC), 13 - Saint-Paul-lez-Durance (France). Dept. de Recherches sur la Fusion Controlee; Bertrand, P. [Universite Henri Poincare, Laboratoire de Physique des Milieux Ionises et Applications (LPMIA), 54 - Vandoeuvre les Nancy (France); Besse, N.; Sonnendruecker, E. [Universite Louis Pasteur, CNRS IRMA, 67 - Strasbourg (France)

    2004-07-01

    This paper reports on 4-dimensional drift kinetic simulations of the slab branch of the Ion Temperature Gradient driven turbulence in a cylinder. In the non-linear regime, the system is found to relax preferentially either via heat transport or via mean sheared flows, depending on the density profile. A strong density gradient appears to be stabilizing both linearly, by increasing the instability threshold, and non linearly, by activating sheared flows. This impedes the relaxation of the profiles and sustains a pressure transport barrier. (authors)

  17. A phenomenological model of the muon density profile on the ground of very inclined air showers

    Science.gov (United States)

    Dembinski, H. P.; Billoir, P.; Deligny, O.; Hebbeker, T.

    2010-09-01

    Ultra-high energy cosmic rays generate extensive air showers in Earth's atmosphere. A standard approach to reconstruct the energy of an ultra-high energy cosmic rays is to sample the lateral profile of the particle density on the ground of the air shower with an array of surface detectors. For cosmic rays with large inclinations, this reconstruction is based on a model of the lateral profile of the muon density observed on the ground, which is fitted to the observed muon densities in individual surface detectors. The best models for this task are derived from detailed Monte-Carlo simulations of the air shower development. We present a phenomenological parametrization scheme which allows to derive a model of the average lateral profile of the muon density directly from a fit to a set of individual Monte-Carlo simulated air showers. The model reproduces the detailed simulations with a high precision. As an example, we generate a muon density model which is valid in the energy range 10 18 eV < E < 10 20 eV and the zenith angle range 60°<θ<90°. We will further demonstrate a way to speed up the simulation of such muon profiles by three orders of magnitude, if only the muons in the shower are of interest.

  18. Effects of Mean Flow Profiles on Instability of a Low-Density Gas Jet Injected into a High-Density Gas

    Science.gov (United States)

    Vedantam, Nanda Kishore

    2003-01-01

    The objective of this study was to investigate the effects of the mean flow profiles on the instability characteristics in the near-injector region of low-density gas jets injected into high-density ambient gas mediums. To achieve this, a linear temporal stability analysis and a spatio-temporal stability analysis of a low-density round gas jet injected vertically upwards into a high-density ambient gas were performed by assuming three different sets of mean velocity and density profiles. The flow was assumed to be isothermal and locally parallel. Viscous and diffusive effects were ignored. The mean flow parameters were represented as the sum of the mean value and a small normal-mode fluctuation. A second order differential equation governing the pressure disturbance amplitude was derived from the basic conservation equations. The first set of mean velocity and density profiles assumed were those used by Monkewitz and Sohn for investigating absolute instability in hot jets. The second set of velocity and density profiles assumed for this study were the ones used by Lawson. And the third set of mean profiles included a parabolic velocity profile and a hyperbolic tangent density profile. The effects of the inhomogeneous shear layer and the Froude number (signifying the effects of gravity) on the temporal and spatio-temporal results for each set of mean profiles were delineated. Additional information is included in the original extended abstract.

  19. Quality and Trace Element Profile of Tunisian Olive Oils Obtained from Plants Irrigated with Treated Wastewater

    Directory of Open Access Journals (Sweden)

    Cinzia Benincasa

    2012-01-01

    Full Text Available In the present work the use of treated wastewater (TWW to irrigate olive plants was monitored. This type of water is characterized by high salinity and retains a substantial amount of trace elements, organic and metallic compounds that can be transferred into the soil and into the plants and fruits. In order to evaluate the impact of TWW on the overall quality of the oils, the time of contact of the olives with the soil has been taken into account. Multi-element data were obtained using ICP-MS. Nineteen elements (Li, B, Na, Mg, Al, K, Ca, Sc, Cr, Mn, Fe, Co, Ni, Cu, Zn, Sr, Mo, Ba and La were submitted for statistical analysis. Using analysis of variance, linear discriminant analysis and principal component analysis it was possible to differentiate between oils produced from different batches of olives whose plants received different types of water. Also, the results showed that there was correlation between the elemental and mineral composition of the water used to irrigate the olive plots and the elemental and mineral composition of the oils.

  20. Field Aligned Currents Derived from Pressure Profiles Obtained from TWINS ENA Images

    Science.gov (United States)

    Wood, K.; Perez, J. D.; McComas, D. J.; Goldstein, J.; Valek, P. W.

    2015-12-01

    Field aligned currents (FACs) that flow from the Earth's magnetosphere into the ionosphere are an important coupling mechanism in the interaction of the solar wind with the Earth's magnetosphere. Assuming pressure balance along with charge conservation yields an expression for the FACs in terms of plasma pressure gradients and pressure anisotropy. The Two Wide-Angle Imaging Neutral Atom Spectrometers (TWINS) mission, the first stereoscopic ENA magnetospheric imager, provides global images of the inner magnetosphere from which ion pressure distributions and pressure anisotropies can be obtained. Following the formulations in Heineman [1990] and using results from TWINS observations, we calculate the distribution of field aligned currents for the 17-18 March 2015 geomagnetic storm in which extended ionospheric precipitation was observed. Initial results for the field aligned currents will be generated assuming an isotropic pitch angle distribution. Global maps of field aligned currents during the main and recovery phase of the storm will be presented. Heinemann, H. (1990), Representations of Currents and Magnetic Fields in Anisotropic Magnetohydrostatic Plasma, J. Geophys. Res., 95, 7789.

  1. Quality and trace element profile of Tunisian olive oils obtained from plants irrigated with treated wastewater.

    Science.gov (United States)

    Benincasa, Cinzia; Gharsallaoui, Mariem; Perri, Enzo; Briccoli Bati, Caterina; Ayadi, Mohamed; Khlif, Moncen; Gabsi, Slimane

    2012-01-01

    In the present work the use of treated wastewater (TWW) to irrigate olive plants was monitored. This type of water is characterized by high salinity and retains a substantial amount of trace elements, organic and metallic compounds that can be transferred into the soil and into the plants and fruits. In order to evaluate the impact of TWW on the overall quality of the oils, the time of contact of the olives with the soil has been taken into account. Multi-element data were obtained using ICP-MS. Nineteen elements (Li, B, Na, Mg, Al, K, Ca, Sc, Cr, Mn, Fe, Co, Ni, Cu, Zn, Sr, Mo, Ba and La) were submitted for statistical analysis. Using analysis of variance, linear discriminant analysis and principal component analysis it was possible to differentiate between oils produced from different batches of olives whose plants received different types of water. Also, the results showed that there was correlation between the elemental and mineral composition of the water used to irrigate the olive plots and the elemental and mineral composition of the oils.

  2. Profiles of Phase-Space Density-like Quantities in Elliptical Galaxies

    CERN Document Server

    Chae, Kyu-Hyun

    2013-01-01

    With the profiles of total mass density rho(r), stellar mass density rho_*(r) and stellar (radial) velocity dispersion sigma_*(r) of ~2,000 elliptical galaxies, we investigate combinations of rho_*(r)/[sigma_*(r)]^epsilon and rho(r)/[sigma_*(r)]^epsilon which have the same dimensionality of phase-space density for epsilon=3 and in that case are respectively referred to as pseudo phase-space (PPS) density Q_*(r) and PPS-like density Q'_*(r). Compared with the density profile rho(r) the quantity rho_*(r)/[sigma_*(r)]^epsilon has at least as large scatter but the quantity rho(r)/[sigma_*(r)]^epsilon has ~4 times smaller scatter of slopes for epsilon=3 within the effective radius R_e. If Q'_*(r) is approximated by Q'_*(r) ~ r^{-chi_e} within R_e, we have chi_e=1.860+/-0.035. Remarkably, this slope matches well the PPS density slope chi_Bertschinger=1.875 predicted by the classical self-similar spherical infall model of a self-gravitating collisionless system and the PPS density slope ~1.9 predicted by N-body simu...

  3. Focus on RNA isolation: obtaining RNA for microRNA (miRNA) expression profiling analyses of neural tissue

    Science.gov (United States)

    Wang, Wang-Xia; Rajeev, Bernard W.; Baldwin, Donald A.; Isett, R. Benjamin; Ren, Na; Stromberg, Arnold; Nelson, Peter T.

    2008-01-01

    MicroRNAs (miRNAs) are present in all known plant and animal tissues and appear to be somewhat concentrated in the mammalian nervous system. Many different miRNA expression profiling platforms have been described. However, relatively little research has been published to establish the importance of ‘upstream’ variables in RNA isolation for neural miRNA expression profiling. We tested whether apparent changes in miRNA expression profiles may be associated with tissue processing, RNA isolation techniques, or different cell types in the sample. RNA isolation was performed on a single brain sample using eight different RNA isolation methods, and results were correlated using a conventional miRNA microarray and then cross-referenced to Northern blots. Differing results were seen between samples obtained using different RNA isolation techniques and between microarray and Northern blot results. Another complication of miRNA microarrays is tissue-level heterogeneity of cellular composition. To investigate this phenomenon, miRNA expression profiles were determined and compared between highly-purified primary cerebral cortical cell preparations of rat primary E15–E18 neurons versus rat primary E15–E18 astrocytes. Finally, to assess the importance of dissecting human brain gray matter from subjacent white matter in cerebral cortical studies, miRNA expression profiles were compared between gray matter and immediately contiguous white matter. The results suggest that for microarray studies, cellular composition is important, and dissecting white matter from gray matter improves the specificity of the results. Based on these data, recommendations for miRNA expression profiling in neural tissues, and considerations worthy of further study, are discussed. PMID:18316046

  4. Role of substituents on the reactivity and electron density profile of diimine ligands: A density functional theory based study

    Indian Academy of Sciences (India)

    Bhakti S Kulkarni; Deepti Mishra; Sourav Pal

    2013-09-01

    In this paper, we study the reactivity of diimines like 2, 2'-bipyridine, 1, l0-phenanthroline and 1, 2, 4-triazines using density-based reactivity descriptors. We discuss the enhancement or diminution in the reactivity of these ligands as a function of two substituent groups, namely methyl (-CH3) group and phenyl (-C6H5) group. The global reactivity descriptors explain the global affinity and philicity of these ligands, whereas the local softness depicts the particular site selectivity. The inter-molecular reactivity trends for the same systems are analysed through the philicity and group philicity indices. The -donor character of these ligands is quantified with the help of electron density profile. In addition, the possible strength of interaction of these ligands with metal ions is supported with actual reaction energies of Ru-L complexes.

  5. Dwarf Galaxy Dark Matter Density Profiles Inferred from Stellar and Gas Kinematics

    CERN Document Server

    Adams, Joshua J; Fabricius, Maximilian H; Bosch, Remco C E van den; Barentine, John C; Bender, Ralf; Gebhardt, Karl; Hill, Gary J; Murphy, Jeremy D; Swaters, R A; Thomas, Jens; van de Ven, Glenn

    2014-01-01

    We present new constraints on the density profiles of dark matter (DM) halos in seven nearby dwarf galaxies from measurements of their integrated stellar light and gas kinematics. The gas kinematics of low mass galaxies frequently suggest that they contain constant density DM cores, while N-body simulations instead predict a cuspy profile. We present a data set of high resolution integral field spectroscopy on seven galaxies and measure the stellar and gas kinematics simultaneously. Using Jeans modeling on our full sample, we examine whether gas kinematics in general produce shallower density profiles than are derived from the stars. Although 2/7 galaxies show some localized differences in their rotation curves between the two tracers, estimates of the central logarithmic slope of the DM density profile, gamma, are generally robust. The mean and standard deviation of the logarithmic slope for the population are gamma=0.67+/-0.10 when measured in the stars and gamma=0.58+/-0.24 when measured in the gas. We als...

  6. Theory for planetary exospheres: II. Radiation pressure effect on exospheric density profiles

    Science.gov (United States)

    Beth, A.; Garnier, P.; Toublanc, D.; Dandouras, I.; Mazelle, C.

    2016-03-01

    The planetary exospheres are poorly known in their outer parts, since the neutral densities are low compared with the instruments detection capabilities. The exospheric models are thus often the main source of information at such high altitudes. We present a new way to take into account analytically the additional effect of the radiation pressure on planetary exospheres. In a series of papers, we present with an Hamiltonian approach the effect of the radiation pressure on dynamical trajectories, density profiles and escaping thermal flux. Our work is a generalization of the study by Bishop and Chamberlain (1989). In this second part of our work, we present here the density profiles of atomic Hydrogen in planetary exospheres subject to the radiation pressure. We first provide the altitude profiles of ballistic particles (the dominant exospheric population in most cases), which exhibit strong asymmetries that explain the known geotail phenomenon at Earth. The radiation pressure strongly enhances the densities compared with the pure gravity case (i.e. the Chamberlain profiles), in particular at noon and midnight. We finally show the existence of an exopause that appears naturally as the external limit for bounded particles, above which all particles are escaping.

  7. Novel analysis technique for measuring edge density fluctuation profiles with reflectometry in the Large Helical Device

    Science.gov (United States)

    Creely, A. J.; Ida, K.; Yoshinuma, M.; Tokuzawa, T.; Tsujimura, T.; Akiyama, T.; Sakamoto, R.; Emoto, M.; Tanaka, K.; Michael, C. A.

    2017-07-01

    A new method for measuring density fluctuation profiles near the edge of plasmas in the Large Helical Device (LHD) has been developed utilizing reflectometry combined with pellet-induced fast density scans. Reflectometer cutoff location was calculated by proportionally scaling the cutoff location calculated with fast far infrared laser interferometer (FIR) density profiles to match the slower time resolution results of the ray-tracing code LHD-GAUSS. Plasma velocity profile peaks generated with this reflectometer mapping were checked against velocity measurements made with charge exchange spectroscopy (CXS) and were found to agree within experimental uncertainty once diagnostic differences were accounted for. Measured density fluctuation profiles were found to peak strongly near the edge of the plasma, as is the case in most tokamaks. These measurements can be used in the future to inform inversion methods of phase contrast imaging (PCI) measurements. This result was confirmed with both a fixed frequency reflectometer and calibrated data from a multi-frequency comb reflectometer, and this method was applied successfully to a series of discharges. The full width at half maximum of the turbulence layer near the edge of the plasma was found to be only 1.5-3 cm on a series of LHD discharges, less than 5% of the normalized minor radius.

  8. Model Predictive Control with Integral Action for Current Density Profile Tracking in NSTX-U

    Science.gov (United States)

    Ilhan, Z. O.; Wehner, W. P.; Schuster, E.; Boyer, M. D.

    2016-10-01

    Active control of the toroidal current density profile may play a critical role in non-inductively sustained long-pulse, high-beta scenarios in a spherical torus (ST) configuration, which is among the missions of the NSTX-U facility. In this work, a previously developed physics-based control-oriented model is embedded in a feedback control scheme based on a model predictive control (MPC) strategy to track a desired current density profile evolution specified indirectly by a desired rotational transform profile. An integrator is embedded into the standard MPC formulation to reject various modeling uncertainties and external disturbances. Neutral beam powers, electron density, and total plasma current are used as actuators. The proposed MPC strategy incorporates various state and actuator constraints directly into the control design process by solving a constrained optimization problem in real-time to determine the optimal actuator requests. The effectiveness of the proposed controller in regulating the current density profile in NSTX-U is demonstrated in closed-loop nonlinear simulations. Supported by the US DOE under DE-AC02-09CH11466.

  9. Fingerprints of the initial conditions on the density profiles of cold and warm dark matter haloes

    CERN Document Server

    Polisensky, E

    2015-01-01

    We use N-body simulations of dark matter haloes in cold dark matter (CDM) and a large set of different warm dark matter (WDM) cosmologies to demonstrate that the spherically averaged density profile of dark matter haloes has a shape that depends on the power spectrum of matter perturbations. Density profiles are steeper in WDM but become shallower at scales less than one percent of the virial radius. Virialization isotropizes the velocity dispersion in the inner regions of the halo but does not erase the memory of the initial conditions in phase space. The location of the observed deviations from CDM in the density profile and in phase space can be directly related to the ratio between the halo mass and the filtering mass and are most evident in small mass haloes, even for a 34 keV thermal relic WDM. The rearrangement of mass within the haloes supports analytic models of halo structure that include angular momentum. We also find evidence of a dependence of the slope of the inner density profile in CDM cosmolo...

  10. The effect of baryons on the inner density profiles of rich clusters

    Science.gov (United States)

    Schaller, Matthieu; Frenk, Carlos S.; Bower, Richard G.; Theuns, Tom; Trayford, James; Crain, Robert A.; Furlong, Michelle; Schaye, Joop; Dalla Vecchia, Claudio; McCarthy, I. G.

    2015-09-01

    We use the `Evolution and assembly of galaxies and their environments' (EAGLE) cosmological simulation to investigate the effect of baryons on the density profiles of rich galaxy clusters. We focus on EAGLE clusters with M200 > 1014 M⊙ of which we have six examples. The central brightest cluster galaxies (BCGs) in the simulation have steep stellar density profiles, ρ*(r) ∝ r-3. Stars dominate the mass density for r Frenk-White (NFW) profile, in remarkable agreement with observations. The dark matter halo itself closely follows the NFW form at all resolved radii (r ≳ 3.0 kpc). The EAGLE BCGs have similar surface brightness and line-of-sight velocity dispersion profiles as the BCGs in the sample of Newman et al., which have the most detailed measurements currently available. After subtracting the contribution of the stars to the central density, Newman et al. infer significantly shallower slopes than the NFW value, in contradiction with the EAGLE results. We discuss possible reasons for this discrepancy, and conclude that an inconsistency between the kinematical model adopted by Newman et al. for their BCGs, which assumes isotropic stellar orbits, and the kinematical structure of the EAGLE BCGs, in which the orbital stellar anisotropy varies with radius and tends to be radially biased, could explain at least part of the discrepancy.

  11. In depth fusion flame spreading with a deuterium-tritium plane fuel density profile for plasma block ignition

    Institute of Scientific and Technical Information of China (English)

    B.Malekynia; S.S.Razavipour

    2012-01-01

    Solid-state fuel ignition was given by Chu and Bobin according to the hydrodynamic theory at x =0 qualitatively.A high threshold energy flux density,i.e.,E* =4.3 x 1012 J/m2,has been reached.Recently,fast ignition by employing clean petawatt-picosecond laser pulses was performed.The anomalous phenomena were observed to be based on suppression of prepulses.The accelerated plasma block was used to ignite deuterium-tritium fuel at solid-state density.The detailed analysis of the thermonuclear wave propagation was investigated.Also the fusion conditions at x ≠ 0 layers were clarified by exactly solving hydrodynamic equations for plasma block ignition.In this paper,the applied physical mechanisms are determined for nonlinear force laser driven plasma blocks,thermonuclear reaction,heat transfer,electron-ion equilibration,stopping power of alpha particles,bremsstrahlung,expansion,density dependence,and fluid dynamics.New ignition conditions may be obtained by using temperature equations,including thc dcnsity profile that is obtained by the continuity equation and expansion velocity.The density is only a function of x and independent of time.The ignition energy flux density,E*t,for the x ≠ 0 layers is 1.95 × 1012 J/m2.Thus threshold ignition energy in comparison with that at x =0 layers would be reduced to less than 50 percent.

  12. Peaked density profiles in neon and lithium doped discharges on FTU

    Energy Technology Data Exchange (ETDEWEB)

    Mazzotta, C., E-mail: cristina.mazzotta@enea.it [Associazione Euratom-ENEA sulla Fusione, Via E. Fermi 45, 00044 Frascati (Italy); Apicella, M.L.; Botrugno, A.; Gabellieri, L.; Marinucci, M.; Mazzitelli, G.; Pucella, G. [Associazione Euratom-ENEA sulla Fusione, Via E. Fermi 45, 00044 Frascati (Italy); Sozzi, C. [Istituto di Fisica dei Plasmi, CNR, Via R. Cozzi 53, 20125 Milano (Italy); Tudisco, O. [Associazione Euratom-ENEA sulla Fusione, Via E. Fermi 45, 00044 Frascati (Italy)

    2014-12-15

    Peaked density profiles are observed in FTU discharges when the recycling condition of the chamber is influenced by the action of the liquid lithium limiter (LLL). Turbulence analysis of lithium doped FTU plasmas has shown that the presence of the light impurity modifies the phase between fluctuating fields responsible for transport and consequently leads to an inward deuterium pinch and outward impurity flux. Analogous peaked discharges were produced by Ne-gas puffing in different L mode plasma scenarios that have been recently obtained on FTU with following plasma parameters: I = 360 kA, B = 5–6.5 T, n{sub e0} = 0.2–1 × 10{sup 20} m{sup −3}, T{sub e0} = 1–4 keV, as well as in similar experiments on other machines. In fact the Ne seeded plasmas show an increase of the peaking factor around 30%. UV spectroscopy measurements confirm that the electron-density peaking arises from a convective flow and cannot be attributed to the contribution of the injected Ne alone. The Ne doped discharges analysis together with lithium conditioned ones is useful to extend the interpretative framework of the particle transport. In this work a comparison of the diffusion coefficient and of the pinch velocity of the two cases is conducted. By using a two-colors scanning interferometer providing very high spatial and time resolution, it is indeed possible to estimate the D and U coefficients of a simple model for the particle flux.

  13. Hollow radial electron density profiles in surface wave discharges. An inside job?

    Science.gov (United States)

    Jimenez-Diaz, Manuel; Rahimi, Sara; Carbone, Emile A. D.; Dijk, Jan Van

    2013-09-01

    In many microwave excited plasmas, there is a part of the discharge (tube) hidden from optical access e.g. because of the metal parts that cover it; it is the region where the transformation occurs between the EM modes found in the (metal) waveguide to modes in the plasma (waveguide). Because in most of cases optical access is not an option here, studies of this region remain scarce. Regardless of this, it is a well-known fact that the discharge tube can easily break due to the high temperatures inside the launcher of surfaguide discharges, which means the temperature is higher there than in other regions of the plasma. In this work, we use a 2D model to show how the inner region changes for increasing power absorbed and electromagnetic wave frequency. The shaping of the EM coupling into the plasma region by the cavity is explored as well. We discuss when the hollow radial profiles for the electron density appear in a surfaguide plasma, and how they are related to the radial inhomogeneity of the EM fields and the plasma properties (e.g. gas temperature). All these results were obtained using the modeling platform Plasimo. Supported by the Dutch Technology Foundation (STW Project Nos. 10497 and 10744) and by the Energy Research Center of the Netherlands (ECN).

  14. Topside-plasmasphere electron density profiles model by using AIS ionosonde measurements and calibrates GPS TEC data

    Science.gov (United States)

    Cesaroni, Claudio; Scotto, Carlo; Ippolito, Alessandro; Ciraolo, Luigi

    2013-04-01

    The Upper Atmosphere Physics group at INGV (Istituto Nazionale di Geofisica e Vulcanologia) developed Autoscala, a computer program for automatic scaling of the critical frequency foF2 and other ionospheric parameters derived from ionograms. Autoscala includes a routine that automatically estimates the electron density profile below F layer peak height hmF2, by adjusting the parameters of a model according to the recorded ionogram [Scotto (2009)]. By integrating this profile we can estimate bottom-side total electron content (bTEC). By means of a calibration technique [Ciraolo et al. (2007)], we are able to obtain calibrated vertical TEC (vTEC) values from GPS measurements over a receiver station. This method permits to estimate biases of the received signal due to transmitter-receiver hardware configuration. These biases must be eliminated from the GPS data in order to calibrate the experimental slant total electron content (sTEC) along the satellite-receiver line-of-sight (LoS). The difference between vTEC and bottom-side TEC (bTEC) permits to evaluate electron content of the topside ionospheric region (tTEC). Starting from tTEC, bottom-side parameters (foF2, hmF2, scale height at hmF2) obtained by ionosonde and O+ - H+ transition level, we can solve a system of equations based on different ionospheric profiler (Chapman, sech-squared and exponential) the solution of which provides ion scale height [Stankov et al. (2003)]. This last factor is sufficient to establish the vertical distribution of electrons in topside and plasmasphere regions. Obtained vertical profiles could be used to develop a new model for real time estimation of TEC and topside electron density distribution. References: Scotto, C. (2009). Electron density profile calculation technique for Autoscala ionogram analysis. Advances in Space Research, 44(6), 756-766. doi:10.1016/j.asr.2009.04.037 Ciraolo, L., et al. "Calibration errors on experimental slant total electron content (TEC) determined with

  15. High-Latitude Topside Ionospheric Vertical Electron-Density-Profile Changes in Response to Large Magnetic Storms

    Science.gov (United States)

    Benson, Robert F.; Fainberg, Joseph; Osherovich, Vladimir A.; Truhlik, Vladimir; Wang, Yongli; Bilitza, Dieter; Fung, Shing F.

    2015-01-01

    Large magnetic-storm induced changes have been detected in high-latitude topside vertical electron-density profiles Ne(h). The investigation was based on the large database of topside Ne(h) profiles and digital topside ionograms from the International Satellites for Ionospheric Studies (ISIS) program available from the NASA Space Physics Data Facility (SPDF) at http://spdf.gsfc.nasa.gov/isis/isis-status.html. This large database enabled Ne(h) profiles to be obtained when an ISIS satellite passed through nearly the same region of space before, during, and after a major magnetic storm. A major goal was to relate the magnetic-storm induced high-latitude Ne(h) profile changes to solar-wind parameters. Thus an additional data constraint was to consider only storms where solar-wind data were available from the NASA/SPDF OMNIWeb database. Ten large magnetic storms (with Dst less than -100 nT) were identified that satisfied both the Ne(h) profile and the solar-wind data constraints. During five of these storms topside ionospheric Ne(h) profiles were available in the high-latitude northern hemisphere and during the other five storms similar ionospheric data were available in the southern hemisphere. Large Ne(h) changes were observed during each one of these storms. Our concentration in this paper is on the northern hemisphere. The data coverage was best for the northern-hemisphere winter. Here Ne(h) profile enhancements were always observed when the magnetic local time (MLT) was between 00 and 03 and Ne(h) profile depletions were always observed between 08 and 10 MLT. The observed Ne(h) deviations were compared with solar-wind parameters, with appropriate time shifts, for four storms.

  16. An improved empirical formulation of an ionosphere bottomside electron density profile thickness parameter

    Science.gov (United States)

    Alazo-Cuartas, K.; Radicella, S. M.

    2017-10-01

    An improved empirical formulation for the characterization of the ;base point; of the bottomside ionospheric electron density profile is proposed. The ;base point; in an ionospheric layer is defined by the electron density profile height where the gradient dN/dh reaches a maximum. The difference between the height of the maximum electron density and the height of the ;base point; is proportional to the ionospheric F2 layer thickness parameter B2. The previous empirical formula links the maximum value of dN/dh to foF2 and M(3000)F2 scaled from the ionograms. The new formulation adds a dependence on the solar zenith angle. The use of the new equation improves substantially the calculation of the B2 thickness parameter used in the NeQuick model.

  17. Comparison of low-density lipoprotein obtained from the Friedewald formula and new formulae in a heterogeneous population

    Directory of Open Access Journals (Sweden)

    César Augusto Guevara-Cuéllar

    2010-12-01

    Full Text Available Introduction: Although the levels of low-density lipoprotein (LDL-C should ideally be determined by beta quantification or enzymatic methods, there are limitations in developing countries. The goal of this study is to compare LDL-C obtained through three formulae (LDL-Cnf with LDL-C obtained through the Friedewald formula (LDL-Cf using LDL-C through enzymatic methods as the most-accepted reference method in clinical practice (LDL-Cr.Methods: A concordance study was carried out in a reference laboratory in Cali, Colombia. The three formulae were (mg/dl: Men with triglycerides under 400 mg/dl: LDL-C = Total Cholesterol (TC - triglycerides (TG /6.5 - 45; men with triglycerides equal to or greater than 400 mg/dl: LDL-C = (TC - (TG / 7 -50 and women: LDL-C = (TC-(TG /6.5 - 70.Results: Three-hundred fifteen values were obtained of which 53% were for women. The mean age and LDL-Cr were 54 years (±15.8 and 112.1 mg/dl (±32.5, respectively. The median (interquartile range, mg/dl of TC, high-density lipoprotein (HDL-C and TG were 204 mg/dl (171-229, 51 mg/dl (41-61, and 156 mg/dl (99-237, respectively. There were no differences between mean values of LDL-Cr and LDL-Cnf (113.48 vs. 112.67 mg/dl; p=0.45. The intraclass correlation coefficient among LDL-Cr and LDL-Cf and LDL-Cnf were high (R=0.93 and 0.92, respectively. The correlation between LDL-Cf and LDL-Cnf was 0.95. There is no difference between the areas under the receiver operating characteristic (ROC curve with the level of LDL-Cr at 160 mg/dl for LDL-Cnf and LDL-Cf. (0.94 vs. 0.93; p=0.27.Conclusion: There is high concordance between LDL-Cf and LDL-Cnf. These formulae could be an alternative when there are limitations to determine LDL-C because of the lack of enzymatic methods or through Friedewald formula due to the absence of HDL-C.

  18. Comparison of low-density lipoprotein obtained from the Friedewald formula and new formulae in a heterogeneous population

    Directory of Open Access Journals (Sweden)

    César Augusto Guevara-Amador

    2011-01-01

    Full Text Available Introduction: Although the levels of low-density lipoprotein (LDL-C should ideally be determined by beta quantification or enzymatic methods, there are limitations in developing countries. The goal of this study is to compare LDL-C obtained through three formulae (LDL-Cnf with LDL-C obtained through the Friedewald formula (LDL-Cf using LDL-C through enzymatic methods as the most-accepted reference method in clinical practice (LDL-Cr. Methods: A concordance study was carried out in a reference laboratory in Cali, Colombia. The three formulae were (mg/dl: Men with triglycerides under 400 mg/dl: LDL-C = Total Cholesterol (TC - triglycerides (TG /6.5 - 45; men with triglycerides equal to or greater than 400 mg/dl: LDL-C = (TC - (TG / 7 -50 and women: LDL-C = (TC-(TG /6.5 - 70. Results: Three-hundred fifteen values were obtained of which 53% were for women. The mean age and LDL-Cr were 54 years (±15.8 and 112.1 mg/dl (±32.5, respectively. The median (interquartile range, mg/dl of TC, high-density lipoprotein (HDL-C and TG were 204 mg/dl (171-229, 51 mg/dl (41-61, and 156 mg/dl (99-237, respectively. There were no differences between mean values of LDL-Cr and LDL-Cnf (113.48 vs. 112.67 mg/dl; p=0.45. The intraclass correlation coefficient among LDL-Cr and LDL-Cf and LDL-Cnf were high (R=0.93 and 0.92, respectively. The correlation between LDL-Cf and LDL-Cnf was 0.95. There is no difference between the areas under the receiver operating characteristic (ROC curve with the level of LDL-Cr at 160 mg/dl for LDL-Cnf and LDL-Cf. (0.94 vs. 0.93; p=0.27. Conclusion: There is high concordance between LDL-Cf and LDL-Cnf. These formulae could be an alternative when there are limitations to determine LDL-C because of the lack of enzymatic methods or through Friedewald formula due to the absence of HDL-C.

  19. Impact of baryon physics on dark matter structures: a detailed simulation study of halo density profiles

    CERN Document Server

    Duffy, Alan R; Kay, Scott T; Vecchia, Claudio Dalla; Battye, Richard A; Booth, C M

    2010-01-01

    The back-reaction of baryons on the dark matter halo density profile is of great interest, not least because it is an important systematic uncertainty when attempting to detect the dark matter. Here, we draw on a large suite of high resolution cosmological hydrodynamical simulations, to systematically investigate this process and its dependence on the baryonic physics associated with galaxy formation. The inclusion of baryons results in significantly more concentrated density profiles if radiative cooling is efficient and feedback is weak. The dark matter halo concentration can in that case increase by as much as 30 (10) per cent on galaxy (cluster) scales. The most significant effects occur in galaxies at high redshift, where there is a strong anti-correlation between the baryon fraction in the halo centre and the inner slope of both the total and the dark matter density profiles. If feedback is weak, isothermal inner profiles form, in agreement with observations of massive, early-type galaxies. However, we ...

  20. MultiDark simulations: the story of dark matter halo concentrations and density profiles

    CERN Document Server

    Klypin, Anatoly; Gottlober, Stefan; Prada, Francisco; Hess, Steffen

    2014-01-01

    Accurately predicting structural properties of dark matter halos is one of the fundamental goals of modern cosmology. We use the new suite of MultiDark cosmological simulations to study the evolution of dark matter halo density profiles, concentrations, and velocity anisotropies. The MultiDark simulations cover a large range of masses 1e10-1e15Msun and volumes upto 50Gpc**3. The total number of dark matter halos in all the simulations exceeds 60 billion. We find that in order to understand the structure of dark matter halos and to make ~1% accurate predictions for density profiles, one needs to realize that halo concentration is more complex than the traditional ratio of the virial radius to the core radius in the NFW profile. For massive halos the averge density profile is far from the NFW shape and the concentration is defined by both the core radius and the shape parameter alpha in the Einasto approximation. Combining results from different redshifts, masses and cosmologies, we show that halos progress thr...

  1. Evolution of density profiles in high-z galaxies: compaction and quenching inside-out

    Science.gov (United States)

    Tacchella, Sandro; Dekel, Avishai; Carollo, C. Marcella; Ceverino, Daniel; DeGraf, Colin; Lapiner, Sharon; Mandelker, Nir; Primack, Joel R.

    2016-05-01

    Using cosmological simulations, we address the interplay between structure and star formation in high-redshift galaxies via the evolution of surface density profiles. Our sample consists of 26 galaxies evolving in the redshift range z = 7 - 1, spanning the stellar mass range (0.2-6.4) × 1010 M⊙ at z = 2. We recover the main trends by stacking the profiles in accordance to their evolution phases. Following a wet compaction event that typically occurs when the stellar mass is ˜109.5 M⊙ at z ˜ 2-4, the gas develops a cusp inside the effective radius, associated with a peak in star formation rate (SFR). The SFR peak and the associated feedback, in the absence of further gas inflow to the centre, marks the onset of gas depletion from the central 1 kpc, leading to quenching of the central SFR. An extended, star-forming ring that forms by fresh gas during the central quenching process shows as a rising specific SFR (sSFR) profile, which is interpreted as inside-out quenching. Before quenching, the stellar density profile grows self-similarly, maintaining its log-log shape because the sSFR is similar at all radii. During the quenching process, the stellar density saturates to a constant value, especially in the inner 1 kpc. The stellar mass and SFR profiles deduced from observations show very similar shapes, consistent with the scenario of wet compaction leading to inside-out quenching and the subsequent saturation of a dense stellar core. We predict a cuspy gas profile during the blue nugget phase, and a gas-depleted core, sometimes surrounded by a ring, in the post-blue nugget phase.

  2. Effect of small scale density perturbations on the formation of dark matter halo profiles

    CERN Document Server

    Pilipenko, S V; Lukash, V N; Mikheeva, E V

    2012-01-01

    With help of a set of toy N-body models of dark halo formation we study the impact of small scale initial perturbations on the inner density profiles of haloes. We find a significant flattening of the inner slope $\\alpha={d \\log \\rho \\over d \\log r}$ to $\\alpha=-0.5$ in some range of scales and amplitudes of the perturbations (while in the case of absence of these perturbations the NFW profile with $\\alpha=-1$ is reproduced). This effect may be responsible for the formation of cuspless galactic haloes.

  3. Effect of small-scale density perturbations on the formation of dark matter halo profiles

    Science.gov (United States)

    Pilipenko, S. V.; Doroshkevich, A. G.; Lukash, V. N.; Mikheeva, E. V.

    2012-11-01

    With the help of a set of toy N-body models of dark halo formation, we study the impact of small-scale initial perturbations on the inner density profiles of haloes. We find a significant flattening of the inner slope ? to α=-0.5 in some range of scales and amplitudes of the perturbations (while in the case of absence of these perturbations, the Navarro-Frenk-White profile with α=-1 is reproduced). This effect may be responsible for the formation of cuspless galactic haloes.

  4. Effect of small scale density perturbations on the formation of dark matter halo profiles

    OpenAIRE

    Pilipenko, S. V.; Doroshkevich, A. G.; Lukash, V. N.; Mikheeva, E. V.

    2012-01-01

    With help of a set of toy N-body models of dark halo formation we study the impact of small scale initial perturbations on the inner density profiles of haloes. We find a significant flattening of the inner slope $\\alpha={d \\log \\rho \\over d \\log r}$ to $\\alpha=-0.5$ in some range of scales and amplitudes of the perturbations (while in the case of absence of these perturbations the NFW profile with $\\alpha=-1$ is reproduced). This effect may be responsible for the formation of cuspless galact...

  5. An Examination of FORMOSAT-3/COSMIC Ionospheric Electron Density Profile: Data Quality Criteria and Comparisons with the IRI Model

    Directory of Open Access Journals (Sweden)

    Kuo-Feng Yang

    2009-01-01

    Full Text Available In this article, we analyze the properties of ionospheric electron density profiling retrieved from FORMOSAT-3/COSMIC radio occultation measurements. Two parameters, namely, the gradient and fluctuation of the topside electron density profile, serve as indicators to quantitatively describe the data quality of the retrieved electron density profile. On the basis of 8 month data (June 2006 - January 2007, we find that on average 93% of the electron density profiles have upper electron density gradients and electron density fluctuations smaller than -0.02 #/m3/m and 0.2, respectively, which can be treated as good data for further analysis. The same results are also achieved for the peak height of the electron density. After removing the questionable data, we compare the general behaviors of the electron density between FORMOSAT-3 and the IRI model. It is found that the global distributions of the peak height and the peak electron density for the FORMOSAT-3/COSMIC data are generally consistent with those for the IRI model. However, a significant difference between their scale heights of the topside electron density profiles is found. It suggests that the shape of the topside electron density profile in the IRI model should be revised accordingly such that it more closely resembles the real situation.

  6. TIDAL STIRRING OF DISKY DWARFS WITH SHALLOW DARK MATTER DENSITY PROFILES: ENHANCED TRANSFORMATION INTO DWARF SPHEROIDALS

    Energy Technology Data Exchange (ETDEWEB)

    Kazantzidis, Stelios [Center for Cosmology and Astro-Particle Physics, Ohio State University, Columbus, OH 43210 (United States); Lokas, Ewa L. [Nicolaus Copernicus Astronomical Center, 00-716 Warsaw (Poland); Mayer, Lucio, E-mail: stelios@mps.ohio-state.edu [Institute for Theoretical Physics, University of Zuerich, CH-8057 Zuerich (Switzerland)

    2013-02-20

    According to the tidal stirring model, late type, rotationally supported dwarfs resembling present day dwarf irregular (dIrr) galaxies can transform into dwarf spheroidals (dSphs) via interactions with Milky-Way-sized hosts. We perform collisionless N-body simulations to investigate for the first time how tidal stirring depends on the dark matter (DM) density distribution in the central stellar region of the progenitor disky dwarf. Specifically, we explore various asymptotic inner slopes {gamma} of the dwarf DM density profiles ({rho}{proportional_to}r {sup -{gamma}}). For a given orbit inside the primary galaxy, rotationally supported dwarfs embedded in DM halos with core-like distributions ({gamma} = 0.2) and mild density cusps ({gamma} = 0.6) demonstrate a substantially enhanced likelihood and efficiency of transformation into dSphs compared to their counterparts with steeper DM density profiles ({gamma} = 1). Such shallow DM distributions are akin to those of observed dIrrs highlighting tidal stirring as a plausible model for the Local Group (LG) morphology-density relation. When {gamma} < 1, a single pericentric passage can induce dSph formation and disky dwarfs on low-eccentricity or large-pericenter orbits are able to transform; these new results allow tidal stirring to explain virtually all known dSphs across a wide range of distances from their hosts. A subset of disky dwarfs initially embedded in DM halos with shallow density profiles are eventually disrupted by the primary; those that survive as dSphs are generally on orbits with lower eccentricities and/or larger pericenters compared to those of typical cold dark matter satellites. The latter could explain the peculiar orbits of several LG dSphs such as Fornax, Leo I, Tucana, and Cetus.

  7. Chemical profile and antimicrobial activity of Boldo (Peumus boldus Molina extracts obtained by compressed carbon dioxide extraction

    Directory of Open Access Journals (Sweden)

    M. Mazutti

    2008-06-01

    Full Text Available This work reports the effects of temperature (20 to 50ºC and pressure (100 to 250 bar on the extraction yield, chemical characteristics and antimicrobial activity of extracts of Peumus boldus Molina obtained by compressed carbon dioxide extraction. Results showed that the extraction variables affect the extraction yield and the chemical distribution of the major compounds present in the extracts. The extracts were chemically analyzed with regard to 1,8-cineole, trans-sabinene, pinocarveol, pinocarvone, 4-terpineol, ascaridole, piperitone oxide, limonene dioxide and n-eicosane in a GC/MSD. Antimicrobial tests demonstrated that the high-pressure CO2 extracts had activity against 13 bacteria and that better action was verified with extracts obtained at a lower CO2 extraction density and a higher temperature.

  8. Comparison of Gene Expression Profile of Epiretinal Membranes Obtained from Eyes with Proliferative Vitreoretinopathy to That of Secondary Epiretinal Membranes

    Science.gov (United States)

    Asato, Ryo; Yoshida, Shigeo; Ogura, Atsushi; Nakama, Takahito; Ishikawa, Keijiro; Nakao, Shintaro; Sassa, Yukio; Enaida, Hiroshi; Oshima, Yuji; Ikeo, Kazuho; Gojobori, Takashi; Kono, Toshihiro; Ishibashi, Tatsuro

    2013-01-01

    Background Proliferative vitreoretinopathy (PVR) is a destructive complication of retinal detachment and vitreoretinal surgery which can lead to severe vision reduction by tractional retinal detachments. The purpose of this study was to determine the gene expression profile of epiretinal membranes (ERMs) associated with a PVR (PVR-ERM) and to compare it to the expression profile of less-aggressive secondary ERMs. Methodology/Principal Findings A PCR-amplified complementary DNA (cDNA) library was constructed using the RNAs isolated from ERMs obtained during vitrectomy. The sequence from the 5′ end was obtained for randomly selected clones and used to generate expressed sequence tags (ESTs). We obtained 1116 nonredundant clusters representing individual genes expressed in PVR-ERMs, and 799 clusters representing the genes expressed in secondary ERMs. The transcriptome of the PVR-ERMs was subdivided by functional subsets of genes related to metabolism, cell adhesion, cytoskeleton, signaling, and other functions, by FatiGo analysis. The genes highly expressed in PVR-ERMs were compared to those expressed in the secondary ERMs, and these were subdivided by cell adhesion, proliferation, and other functions. Querying 10 cell adhesion-related genes against the STRING database yielded 70 possible physical relationships to other genes/proteins, which included an additional 60 genes that were not detected in the PVR-ERM library. Of these, soluble CD44 and soluble vascular cellular adhesion molecule-1 were significantly increased in the vitreous of patients with PVR. Conclusions/Significance Our results support an earlier hypothesis that a PVR-ERM, even from genomic points of view, is an aberrant form of wound healing response. Genes preferentially expressed in PVR-ERMs may play an important role in the progression of PVR and could be served as therapeutic targets. PMID:23372684

  9. Density profiles of Ar adsorbed in slits of CO2: Spontaneous symmetry breaking revisited

    Science.gov (United States)

    Szybisz, Leszek; Sartarelli, Salvador A.

    2008-03-01

    A recently reported symmetry breaking of density profiles of fluid argon confined by two parallel solid walls of carbon dioxide is studied. The calculations are performed in the framework of a nonlocal density functional theory. It is shown that the existence of such asymmetrical solutions is restricted to a special choice for the adsorption potential, where the attraction of the solid-fluid interaction is reduced by the introduction of a hard-wall repulsion. The behavior as a function of the slit's width is also discussed. All the results are placed in the context of the current knowledge on this matter.

  10. Determination of density profiles of unevenly compressed wood of Po­pu­lus tremula using the X – RAY DENSE – LAB laboratory device

    Directory of Open Access Journals (Sweden)

    Aleš Dejmal

    2009-01-01

    Full Text Available The paper deals with the measuring of the density profile of unevenly pressed wood of European aspen (Populus tremula L.. The main aim of the work is to examine in an experimental way the possibilities of using the X – RAY DENSE – LAB laboratory equipment designed for the determination of density profiles of agglomerated and plied large-area materials. The work uses the X – RAY DENSE – LAB equipment to determine the density profile of the cross-section of unevenly pressed aspen wood, plasticized hydrothermically, without the presence of chemical substances. The work also presents calculations of the level of compression/densification in dependence on the density and it describes the factors that can influence the density profile of compressed/densified wood; at the same time, it presents the possible ways to determine the density profile in the cross-section. Further, it includes the creation of the methodology for sample preparation so that the results do not get distorted during measuring. It describes the preparation of sample pieces, the orientation of the anatomic structure, the methodology of pressing, air conditioning, sample preparation, their measuring and analysis. The paper also describes the theory and the principles of measuring with use of X – RAY DENSE – LAB and its calibration. The paper analyses the obtained results of density profiles and searches for and describes the causes of the uneven distribution of the density in the cross-section. It concludes by summarizing the results and recommending the procedure for future measuring.

  11. Modeling of 2-dimensional and 3-dimensional etch profiles in high density plasma reactors

    Energy Technology Data Exchange (ETDEWEB)

    Hoekstra, R.J.; Kushner, M.J. [Univ. of Illinois, Urbana, IL (United States). Dept. of Electrical and Computer Engineering; Sukharev, V. [LSI Logic Corp., Santa Clara, CA (United States)

    1997-12-31

    In order to model the plasma etching process from plasma generation to etch profile evolution, processes from the macroscopic reactor scale to the microscopic feature scale must be simulated. An integrated monte Carlo feature Profile Model (MCFPM) has been developed to examine the time evolution of etch profiles in high density plasma systems. By integrating the MCFPM with the Hybrid Plasma Equipment Model (HPEM), the authors are able to self-consistently determine the etch profiles for specific regions on the wafer in specific reactor geometry with specified parameters for power, chemistry, gas flow, etc. The latest improvements of the model include the effects of incoming particle angle and energy on reaction and reflection based on the results of molecular dynamics simulations. Increase the specular reflection of high energy particles leads to more vertical sidewalls and corner clearing but can also cause deformation of the bottom of the profile surface. For Chlorine etching of 2D and 3D profiles in polysilicon, the model results will be compared to experimental results in an inductively couple etching reactor. The changes due to radial location as well as sub wafer and superwafer topography be examined.

  12. Modulation of solar flare particles and track density profiles in gas-rich meteorite grains

    Science.gov (United States)

    Lee, M. A.

    1976-01-01

    A solution is presented to the problem concerning the time-averaged solar flare particle flux as a function of kinetic energy and distance from the sun for a given particle injection spectrum at the sun within the framework of standard diffusion-convection-adiabatic deceleration theory with the diffusion coefficient independent of distance from the sun. Results of the calculations which give best agreement with observations at 1 AU are presented and discussed, with particular reference to their implications for gas-rich meteorites. Normalization at the orbit of earth is achieved via observed track density versus depth profiles in lunar vug crystals. It is shown that if gas-rich meteorite grains were irradiated in the asteroid belt and if source and modulation parameters have changed little since irradiation, the track density should be 'harder' than the lunar vug profile by about 0.2-0.3 in the index. Quantitative estimation of solar flare particle exposure ages is discussed.

  13. MultiDark simulations: the story of dark matter halo concentrations and density profiles

    Science.gov (United States)

    Klypin, Anatoly; Yepes, Gustavo; Gottlöber, Stefan; Prada, Francisco; Heß, Steffen

    2016-04-01

    Predicting structural properties of dark matter haloes is one of the fundamental goals of modern cosmology. We use the suite of MultiDark cosmological simulations to study the evolution of dark matter halo density profiles, concentrations, and velocity anisotropies. We find that in order to understand the structure of dark matter haloes and to make 1-2 per cent accurate predictions for density profiles, one needs to realize that halo concentration is more complex than the ratio of the virial radius to the core radius in the Navarro-Frenk-White (NFW) profile. For massive haloes, the average density profile is far from the NFW shape and the concentration is defined by both the core radius and the shape parameter α in the Einasto approximation. We show that haloes progress through three stages of evolution. They start as rare density peaks and experience fast and nearly radial infall that brings mass closer to the centre, producing a highly concentrated halo. Here, the halo concentration increases with increasing halo mass and the concentration is defined by the α parameter with a nearly constant core radius. Later haloes slide into the plateau regime where the accretion becomes less radial, but frequent mergers still affect even the central region. At this stage, the concentration does not depend on halo mass. Once the rate of accretion and merging slows down, haloes move into the domain of declining concentration-mass relation because new accretion piles up mass close to the virial radius while the core radius is staying constant. Accurate analytical fits are provided.

  14. Double-Humped Transverse Density Profile in Two-Dimensional Chute Flow with Rough Sidewalls

    Institute of Scientific and Technical Information of China (English)

    HU Guo-Qi; ZHANG Xun-Sheng; BAO De-Song; TANG Xiao-Wei

    2006-01-01

    @@ We study a two-dimensional granular rapid flow with rough sidewalls stuck with the same size discs by molecular dynamics simulation. A transient state of the double-humped density profile in the flowing process has been found, which appears and moves as travelling wave and is the same as the phenomena in the recent experiments [Acta Phys. Sin. 53 (2004) 3389 (in Chinese)].

  15. Density Profiles of CDM Microhalos and their Implications for Annihilation Boost Factors

    CERN Document Server

    Anderhalden, Donnino

    2013-01-01

    In a standard cold dark matter (CDM) cosmology, microhalos at the CDM cutoff scale are the first and smallest objects expected to form in the universe. Here we present results of high resolution simulations of three representative roughly Earth-mass microhalos in order to determine their inner density profile. We find that CDM microhalos in simulations without a cutoff in the power spectrum roughly follow the NFW density profile, just like the much larger CDM halos on galaxy and galaxy cluster scales. But having a cutoff in the initial power spectrum at a typical neutralino free streaming scale of $10^{-7} M_{\\odot}$ makes their inner density profiles considerably steeper, i.e. $\\rho \\propto r^{-(1.3-1.4)}$, in good agreement with the results from Ishiyama et al. (2010). An extrapolation of the halo and subhalo mass functions down to the cutoff scale indicates that microhalos are extremely abundant throughout the present day dark matter distribution and might contribute significantly to indirect dark matter d...

  16. A mass-dependent density profile for dark matter haloes including the influence of galaxy formation

    CERN Document Server

    Di Cintio, Arianna; Dutton, Aaron A; Macciò, Andrea V; Stinson, Greg S; Knebe, Alexander

    2014-01-01

    We introduce a mass dependent density profile to describe the distribution of dark matter within galaxies, which takes into account the stellar-to-halo mass dependence of the response of dark matter to baryonic processes. The study is based on the analysis of hydrodynamically simulated galaxies from dwarf to Milky Way mass, drawn from the MaGICC project, which have been shown to match a wide range of disk scaling relationships. We find that the best fit parameters of a generic double power-law density profile vary in a systematic manner that depends on the stellar-to-halo mass ratio of each galaxy. Thus, the quantity Mstar/Mhalo constrains the inner ($\\gamma$) and outer ($\\beta$) slopes of dark matter density, and the sharpness of transition between the slopes($\\alpha$), reducing the number of free parameters of the model to two. Due to the tight relation between stellar mass and halo mass, either of these quantities is sufficient to describe the dark matter halo profile including the effects of baryons. The ...

  17. Role of Density Profiles for the Nonlinear Propagation of Intense Laser Beam through Plasma Channel

    Directory of Open Access Journals (Sweden)

    Sonu Sen

    2014-01-01

    Full Text Available In this work role of density profiles for the nonlinear propagation of intense laser beam through plasma channel is analyzed. By employing the expression for the dielectric function of different density profile plasma, a differential equation for beamwidth parameter is derived under WKB and paraxial approximation. The laser induces modifications of the dielectric function through nonlinearities. It is found that density profiles play vital role in laser-plasma interaction studies. To have numerical appreciation of the results the propagation equation for plasma is solved using the fourth order Runge-Kutta method for the initial plane wave front of the beam, using boundary conditions. The spot size of the laser beam decreases as the beam penetrates into the plasma and significantly adds self-focusing in plasma. This causes the laser beam to become more focused by reduction of diffraction effect, which is an important phenomenon in inertial confinement fusion and also for the understanding of self-focusing of laser pulses. Numerical computations are presented and discussed in the form of graphs for typical parameters of laser-plasma interaction.

  18. Identification of pathogens and virulence profile of Rhodococcus equi and Escherichia coli strains obtained from sand of parks

    Directory of Open Access Journals (Sweden)

    M.C. Fernandes

    2013-01-01

    Full Text Available The identification of pathogens of viral (Rotavirus, Coronavirus, parasitic (Toxocara spp. and bacterial (Escherichia coli, Salmonella spp., Rhodococcus equi origin shed in feces, and the virulence profile of R. equi and E. coli isolates were investigated in 200 samples of sand obtained from 40 parks, located in central region of state of Sao Paulo, Brazil, using different diagnostic methods. From 200 samples analyzed, 23 (11.5% strains of R. equi were isolated. None of the R. equi isolates showed a virulent (vapA gene or intermediately virulent (vapB gene profiles. Sixty-three (31.5% strains of E. coli were identified. The following genes encoding virulence factors were identified in E. coli: eae, bfp, saa, iucD, papGI, sfa and hly. Phylogenetic classification showed that 63 E. coli isolates belonged to groups B1 (52.4%, A (25.4% and B2 (22.2%. No E. coli serotype O157:H7 was identified. Eggs of Toxocara sp. were found in three parks and genetic material of bovine Coronavirus was identified in one sample of one park. No Salmonella spp. and Rotavirus isolates were identified in the samples of sand. The presence of R. equi, Toxocara sp, bovine Coronavirus and virulent E. coli isolates in the environment of parks indicates that the sanitary conditions of the sand should be improved in order to reduce the risks of fecal transmission of pathogens of zoonotic potential to humans in these places.

  19. Identification of pathogens and virulence profile of Rhodococcus equi and Escherichia coli strains obtained from sand of parks.

    Science.gov (United States)

    Fernandes, M C; Takai, S; Leite, D S; Pinto, J P A N; Brandão, P E; Santarém, V A; Listoni, F J P; Da Silva, A V; Ribeiro, M G

    2013-01-01

    The identification of pathogens of viral (Rotavirus, Coronavirus), parasitic (Toxocara spp.) and bacterial (Escherichia coli, Salmonella spp., Rhodococcus equi) origin shed in feces, and the virulence profile of R. equi and E. coli isolates were investigated in 200 samples of sand obtained from 40 parks, located in central region of state of Sao Paulo, Brazil, using different diagnostic methods. From 200 samples analyzed, 23 (11.5%) strains of R. equi were isolated. None of the R. equi isolates showed a virulent (vapA gene) or intermediately virulent (vapB gene) profiles. Sixty-three (31.5%) strains of E. coli were identified. The following genes encoding virulence factors were identified in E. coli: eae, bfp, saa, iucD, papGI, sfa and hly. Phylogenetic classification showed that 63 E. coli isolates belonged to groups B1 (52.4%), A (25.4%) and B2 (22.2%). No E. coli serotype O157:H7 was identified. Eggs of Toxocara sp. were found in three parks and genetic material of bovine Coronavirus was identified in one sample of one park. No Salmonella spp. and Rotavirus isolates were identified in the samples of sand. The presence of R. equi, Toxocara sp, bovine Coronavirus and virulent E. coli isolates in the environment of parks indicates that the sanitary conditions of the sand should be improved in order to reduce the risks of fecal transmission of pathogens of zoonotic potential to humans in these places.

  20. The masses and density profiles of halos in a LCDM galaxy formation simulation

    CERN Document Server

    Schaller, Matthieu; Bower, Richard G; Theuns, Tom; Jenkins, Adrian; Schaye, Joop; Crain, Robert A; Furlong, Michelle; Vecchia, Claudio Dalla; McCarthy, I G

    2014-01-01

    We investigate the internal structure and density profiles of halos of mass $10^{10}-10^{14}~M_\\odot$ in the Evolution and Assembly of Galaxies and their Environment (EAGLE) simulations. These follow the formation of galaxies in a $\\Lambda$CDM Universe and include a treatment of the baryon physics thought to be relevant. The EAGLE simulations reproduce the observed present-day galaxy stellar mass function, as well as many other properties of the galaxy population as a function of time. We find significant differences between the masses of halos in the EAGLE simulations and in simulations that follow only the dark matter component. Nevertheless, halos are well described by the Navarro-Frenk-White (NFW) density profile at radii larger than ~5% of the virial radius but, closer to the centre, the presence of stars can produce cuspier profiles. Central enhancements in the total mass profile are most important in halos of mass $10^{12}-10^{13}M_\\odot$, where the stellar fraction peaks. Over the radial range where t...

  1. Variations in a Universal Density Profile for the Milky Way's Dwarf Spheroidal Galaxies

    Science.gov (United States)

    Jardel, John; Gebhardt, K.

    2014-01-01

    On the largest scales, the Cold Dark Matter (CDM) paradigm for structure formation has enjoyed remarkable success in describing the universe we live in. The current frontier in our knowledge of galaxy formation is at the low-mass level. Here we find disagreement between theory and observations in a number of interesting cases. One such problem that has received considerable attention is the debate over the shape of the dark matter density profiles in the Milky Way's dwarf spheroidal (dSph) galaxies, known as the core/cusp problem. CDM simulations predict every halo should have a cuspy profile with an inner logarithmic slope of -1, but some observers have found that profiles with constant density inner cores are preferred. However, a major weakness of this previous work is that the dynamical models constructed to measure the mass distribution have had to assume a parameterization for the dark matter profile--exactly the thing one wishes to measure. For my thesis I introduced a new modeling technique, based on Schwarzschild's method, that instead calculates the dark matter profile non-parametrically. Applying these models to five of the Milky Way's dSphs I found a variety of profile shapes including cores, cusps, and other completely unexpected shapes. When scaled to a common normalization, however, I found the combined profile appears to follow an approximate power law with slope -1. The results of this averaging suggest that the individual formation histories of each galaxy produce differing dark matter profiles, but with a net result that is similar to CDM predictions. To better understand the role baryons play in this process, I compare my results to recent hydrodynamical simulations of the formation of dwarf galaxies. Together, my results and the simulations suggest a trend of flatter profiles in galaxies where more stars have formed. This implies that star formation and dark matter halos are linked through the effects of supernova-induced outflows which are

  2. CLASH-VLT: The mass, velocity-anisotropy, and pseudo-phase-space density profiles of the z=0.44 galaxy cluster MACS 1206.2-0847

    CERN Document Server

    Biviano, A; Balestra, I; Mercurio, A; Girardi, M; Nonino, M; Grillo, C; Scodeggio, M; Lemze, D; Kelson, D; Umetsu, K; Postman, M; Zitrin, A; Czoske, O; Ettori, S; Lombardi, M; Maier, C; Medezinski, E; Mei, S; Presotto, V; Tozzi, P; Ziegler, B; Annunziatella, M; Bartelmann, M; Benitez, N; Bradley, L; Brescia, M; Broadhurst, T; Coe, D; Demarco, R; Donahue, M; Ford, H; Gobat, R; Graves, G; Koekemoer, A; Kuchner, U; Melchior, P; Meneghetti, M; Merten, J; Moustakas, L; Munari, E; Regos, E; Sartoris, B; Seitz, S; Zheng, W

    2013-01-01

    We use an unprecedented data-set of about 600 redshifts for cluster members, obtained as part of a VLT/VIMOS large programme, to constrain the mass profile of the z=0.44 cluster MACS J1206.2-0847 over the radial range 0-5 Mpc (0-2.5 virial radii) using the MAMPOSSt and Caustic methods. We then add external constraints from the gravitational lensing analysis of Umetsu et al. (2012). We invert the Jeans equation to obtain the velocity-anisotropy profiles of cluster members. With the mass-density and velocity-anisotropy profiles we then obtain the first determination of a cluster pseudo-phase-space density profile. The kinematics and lensing determinations of the cluster mass profile are in excellent agreement. This is very well fitted by a NFW model with mass M200=(1.4 +- 0.2) 10^15 Msun and concentration c200=6 +- 1, only slightly higher than theoretical expectations. Other mass profile models also provide acceptable fits to our data, of (slightly) lower (Burkert, Hernquist, and Softened Isothermal Sphere) or ...

  3. Computational modeling of bone density profiles in response to gait: a subject-specific approach.

    Science.gov (United States)

    Pang, Henry; Shiwalkar, Abhishek P; Madormo, Chris M; Taylor, Rebecca E; Andriacchi, Thomas P; Kuhl, Ellen

    2012-03-01

    The goal of this study is to explore the potential of computational growth models to predict bone density profiles in the proximal tibia in response to gait-induced loading. From a modeling point of view, we design a finite element-based computational algorithm using the theory of open system thermodynamics. In this algorithm, the biological problem, the balance of mass, is solved locally on the integration point level, while the mechanical problem, the balance of linear momentum, is solved globally on the node point level. Specifically, the local bone mineral density is treated as an internal variable, which is allowed to change in response to mechanical loading. From an experimental point of view, we perform a subject-specific gait analysis to identify the relevant forces during walking using an inverse dynamics approach. These forces are directly applied as loads in the finite element simulation. To validate the model, we take a Dual-Energy X-ray Absorptiometry scan of the subject's right knee from which we create a geometric model of the proximal tibia. For qualitative validation, we compare the computationally predicted density profiles to the bone mineral density extracted from this scan. For quantitative validation, we adopt the region of interest method and determine the density values at fourteen discrete locations using standard and custom-designed image analysis tools. Qualitatively, our two- and three-dimensional density predictions are in excellent agreement with the experimental measurements. Quantitatively, errors are less than 3% for the two-dimensional analysis and less than 10% for the three-dimensional analysis. The proposed approach has the potential to ultimately improve the long-term success of possible treatment options for chronic diseases such as osteoarthritis on a patient-specific basis by accurately addressing the complex interactions between ambulatory loads and tissue changes.

  4. Firn density profile at Megadunes, East Antarctica, calls for an improved densification model for low accumulation sites.

    Science.gov (United States)

    Suwa, M.; Severinghaus, J. P.

    2004-12-01

    We report a density profile of the firn at Megadunes, East Antarctica (80o78'S; 124o50'E). The Megadunes site is characterized by a low mass accumulation rate (2.9 g/cm2/yr) and cold temperature (mean annual = -49.5oC). Validating existing firn densification models using a density profile of such a site is important because such models, either purely empirical or mechanistic, have been calibrated with few sites that are analogous to a glacial condition (ultralow accumulation and temperature). We make use of CO2 concentrations in the lock-in (or non-diffusive) zone to obtain the accumulation rate, assuming that the gas in the lock-in zone ages at the same rate as the surrounding ice [Battle et al., 1996], and assuming that the gas enclosure rate must equal the long-term mean accumulation rate. This estimate is preliminary and may change when results from beta analysis of cores become available. Our density profile shows that the widely used pure empirical model by Herron and Langway [1980] overestimates the close-off depth by 16 %, and the semi-mechanistic model by Pimienta and Barnola [Barnola et al., 1991] also overestimates the close-off depth by 26 %. Our study at the Megadunes site indicates that the δ 15N of N2 paradox for glacial ice from East Antarctica would have partly resulted from a poorly calibrated densification model for a `glacial-like' condition and a thick convective zone as we observed at the Megadunes site [Severinghaus et al., in prep].

  5. Radiation-damped profiles of extremely high column density neutral hydrogen: implications of cosmic reionization

    Science.gov (United States)

    Bach, Kiehunn

    2017-01-01

    Incorporating the time-dependent second-order perturbation theory for the Lyman scattering cross-section, we investigate the intergalactic absorption profiles of extremely high column density systems near the end of cosmic reionization. Assuming a representative set of the redshift distribution of neutral hydrogen, we quantitatively examined the impact of inhomogeneous density on the intrinsic absorption profiles. The cumulative absorption by neutral patches in the line of sight mainly affects the far off-centre region of the red damping wing, but the effect is not significant. The shape of the line centre can be modified by the near-zone distribution due to high opacities of the near-resonance scattering. On the other hand, the HWHM (half width at half-maximum) as an effective line width is relatively less sensitive to the local inhomogeneity. Specifically, when the two local damping wings of Lyα and Lyβ are close in spectra of the strongly damped systems, accurate profiles of both lines are required. In the case of N_{H I}≲ 10^{21} { cm^{-2}}, the two-level approximation is marginally applicable for the damping wing fit within 5 - 7 per cent errors. However, as the local column density reaches N_{H I}˜ 10^{22.3} { cm^{-2}}, this classical approximation yields a relative error of a 10 per cent overestimation in the red wing and a 20 per cent underestimation in the blue wing of Lyα. If severe extinction by the Lyα forests is carefully subtracted, the intrinsic absorption profile will provide a better constraint on the local ionized states. For practical applications, an analytic fitting function for the Lyβ scattering is derived.

  6. Radiation Damped Profiles of Extremely High Column Density Neutral Hydrogen : Implications of Cosmic Reionization

    Science.gov (United States)

    Bach, Kiehunn

    2016-09-01

    Incorporating the time-dependent second-order perturbation theory for the Lyman scattering cross-section, we investigate the intergalactic absorption profiles of extremely high column density systems near the end of cosmic reionization. Assuming a representative set of the redshift distribution of neutral hydrogen, we quantitatively examined the impact of inhomogeneous density on the intrinsic absorption profiles. The cumulative absorption by neutral patches in the line-of-sight mainly affects the far off-center region of the red damping wing, but the effect is not significant. The shape of the line-center can be modified by the near-zone distribution due to high opacities of the near-resonance scattering. On the other hand, the HWHM (half width at half maximum) as an effective line-width is relatively less sensitive to the local inhomogeneity. Specifically, when the two local damping wings of Lyα and Lyβ are close in spectra of the strongly damped systems, accurate profiles of both lines are required. In the case of N HI ≲ 1021 cm-2, the two-level approximation is marginally applicable for the damping wing fit within 5 - 7% errors. However, as the local column density reaches N HI ˜ 1022.3 cm-2, this classical approximation yields a relative error of a 10% overestimation in the red wing and a 20% underestimation in the blue wing of Lyα. If severe extinction by the Lyα forests is carefully subtracted, the intrinsic absorption profile will provide a better constraint on the local ionized states. For practical applications, an analytic fitting function for the Lyβ scattering is derived.

  7. Antioxidant activity, cytotoxic activity and metabolic profiling of juices obtained from saffron (Crocus sativus L.) floral by-products.

    Science.gov (United States)

    Tuberoso, Carlo I G; Rosa, Antonella; Montoro, Paola; Fenu, Maurizio Antonio; Pizza, Cosimo

    2016-05-15

    Juices obtained from cold-pressed saffron (Crocus sativus L.) floral by-products were evaluated as a potential source of compounds with antioxidant and cytotoxic activities. Floral by-products were split in two batches for extraction 24 and 48h after flower harvesting, respectively. The in vitro anti-oxidant activity of these extracts was tested using the FRAP and DPPH assays, and two biological models of lipid oxidation (activity in preventing cholesterol degradation and protection against Cu(2+)-mediated degradation of the liposomal unsaturated fatty acids). The cytotoxic activity was evaluated using the MTT assay. The results show that extracts obtained 48h post-harvest contained higher levels of total polar phenols and had the highest antioxidant activity in all of the performed assays. The LC-DAD and LC-ESI-(HR)MS(n) metabolic profiles showed high levels of kaempferol derivatives and anthocyanins. This study suggests that juices from saffron floral by-products could potentially be used to develop new products for the food and health industry.

  8. Classification of Spanish white wines using their electrophoretic profiles obtained by capillary zone electrophoresis with amperometric detection.

    Science.gov (United States)

    Arribas, Alberto Sánchez; Martínez-Fernández, Marta; Moreno, Mónica; Bermejo, Esperanza; Zapardiel, Antonio; Chicharro, Manuel

    2014-06-01

    A method was developed for the simultaneous detection of eight polyphenols (t-resveratrol, (+)-catechin, quercetin and p-coumaric, caffeic, sinapic, ferulic, and gallic acids) by CZE with electrochemical detection. Separation of these polyphenols was achieved within 25 min using a 200 mM borate buffer (pH 9.4) containing 10% methanol as separation electrolyte. Amperometric detection of polyphenols was carried out with a glassy carbon electrode (GCE) modified with a multiwalled carbon nanotubes (CNT) layer obtained from a dispersion of CNT in polyethylenimine. The excellent electrochemical properties of this modified electrode allowed the detection and quantification of the selected polyphenols in white wines without any pretreatment step, showing remarkable signal stability despite the presence of potential fouling substances in wine. The electrophoretic profiles of white wines, obtained using this methodology, have proven to be useful for the classification of these wines by means of chemometric multivariate techniques. Principal component analysis and discriminant analysis allowed accurate classification of wine samples on the basis of their grape varietal (verdejo and airén) using the information contained in selected zones of the electropherogram. The utility of the proposed CZE methodology based on the electrochemical response of CNT-modified electrodes appears to be promising in the field of wine industry and it is expected to be successfully extended to classification of a wider range of wines made of other grape varietals. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  9. Radial Surface Density Profiles of Gas and Dust in the Debris Disk Around 49 Ceti

    Science.gov (United States)

    Hughes, A. Meredith; Lieman-Sifry, Jesse; Flaherty, Kevin M.; Daley, Cail M.; Roberge, Aki; Kospal, Agnes; Moor, Attila; Kamp, Inga; Wilner, David J.; Andrews, Sean M.; hide

    2017-01-01

    We present approximately 0".4 resolution images of CO(3-2) and associated continuum emission from the gas-bearing debris disk around the nearby A star 49 Ceti, observed with the Atacama Large Millimeter/Submillimeter Array (ALMA). We analyze the ALMA visibilities in tandem with the broadband spectral energy distribution to measure the radial surface density profiles of dust and gas emission from the system. The dust surface density decreases with radius between approximately 100 and 310 au, with a marginally significant enhancement of surface density at a radius of approximately 110 au. The SED requires an inner disk of small grains in addition to the outer disk of larger grains resolved by ALMA. The gas disk exhibits a surface density profile that increases with radius, contrary to most previous spatially resolved observations of circumstellar gas disks. While approximately 80% of the CO flux is well described by an axisymmetric power-law disk in Keplerian rotation about the central star, residuals at approximately 20% of the peak flux exhibit a departure from axisymmetry suggestive of spiral arms or a warp in the gas disk. The radial extent of the gas disk (approx. 220 au) is smaller than that of the dust disk (approx. 300 au), consistent with recent observations of other gasbearing debris disks. While there are so far only three broad debris disks with well characterized radial dust profiles at millimeter wavelengths, 49 Ceti's disk shows a markedly different structure from two radially resolved gas-poor debris disks, implying that the physical processes generating and sculpting the gas and dust are fundamentally different.

  10. Body mass index, general fatness, lipid profile and bone mineral density in young women and men

    Directory of Open Access Journals (Sweden)

    Kopiczko Anna

    2017-03-01

    Full Text Available The bone tissue is metabolically active. Throughout the entire life, it undergoes changes in the form of bone resorption processes which are successive, with the participation of the resorbing cells and bone formation processes. The aim of the study was to evaluate mineral density and bone mass tissue and the lipid profile, BMI, total body fat in young females and males. The study involved 100 people (50 females and 50 males studying in Warsaw at the age of 23,2 ± 4,0 years. The densitometry method of the forearm was used for the assessment of bone mineral density (BMD and bone mass (BMC. The method of bioelectrical impedance was used for the assessment of body components. Basic body dimensions and indicators were assessed using anthropometric measurements. Body height, body mass and the needs for the densitometry study of the forearm were measured. The total cholesterol concentration was determined in the blood serum using diagnostic kits, as well as high-density lipoprotein (HDL-C and triglycerides. The concentration of the low-density lipoprotein (LDL-C was calculated. While in men the occurrence of a significant, positive correlation was stated between the concentration of the HDL cholesterol fraction and the mineral density and T-score index in the ultra-distal point, the analysis of the compounds of mineral density (BMD, bone mass (BMC of the forearm, T-score index with somatic features in women showed a significant, positive relation between the body weight and the bone mass mineral density and T-score indicator in the proximal point. Also, a significant weak, positive correlation was observed between the BMI, the mineral density and T-score indicator in the proximal point. In men, the occurrence of significant, positive correlations was stated between the body weight and BMC, BMD, T-score indicator in the proximal point of the forearm bone and ultra-distal point. Similar relations were observed between the BMI, mineral density, T

  11. Statistical evaluation of fatty acid profile and cholesterol content in fish (common carp) lipids obtained by different sample preparation procedures.

    Science.gov (United States)

    Spiric, Aurelija; Trbovic, Dejana; Vranic, Danijela; Djinovic, Jasna; Petronijevic, Radivoj; Matekalo-Sverak, Vesna

    2010-07-01

    Studies performed on lipid extraction from animal and fish tissues do not provide information on its influence on fatty acid composition of the extracted lipids as well as on cholesterol content. Data presented in this paper indicate the impact of extraction procedures on fatty acid profile of fish lipids extracted by the modified Soxhlet and ASE (accelerated solvent extraction) procedure. Cholesterol was also determined by direct saponification method, too. Student's paired t-test used for comparison of the total fat content in carp fish population obtained by two extraction methods shows that differences between values of the total fat content determined by ASE and modified Soxhlet method are not statistically significant. Values obtained by three different methods (direct saponification, ASE and modified Soxhlet method), used for determination of cholesterol content in carp, were compared by one-way analysis of variance (ANOVA). The obtained results show that modified Soxhlet method gives results which differ significantly from the results obtained by direct saponification and ASE method. However the results obtained by direct saponification and ASE method do not differ significantly from each other. The highest quantities for cholesterol (37.65 to 65.44 mg/100 g) in the analyzed fish muscle were obtained by applying direct saponification method, as less destructive one, followed by ASE (34.16 to 52.60 mg/100 g) and modified Soxhlet extraction method (10.73 to 30.83 mg/100 g). Modified Soxhlet method for extraction of fish lipids gives higher values for n-6 fatty acids than ASE method (t(paired)=3.22 t(c)=2.36), while there is no statistically significant difference in the n-3 content levels between the methods (t(paired)=1.31). The UNSFA/SFA ratio obtained by using modified Soxhlet method is also higher than the ratio obtained using ASE method (t(paired)=4.88 t(c)=2.36). Results of Principal Component Analysis (PCA) showed that the highest positive impact to

  12. A procedure to analyze nonlinear density waves in Saturn's rings using several occultation profiles

    CERN Document Server

    Rappaport, N J; French, R G; Marouf, E A; McGhee, C A

    2010-01-01

    Cassini radio science experiments have provided multiple occultation optical depth profiles of Saturn's rings that can be used in combination to analyze density waves. This paper establishes an accurate procedure of inversion of the wave profiles to reconstruct the wave kinematic parameters as a function of semi-major axis, in the nonlinear regime. This procedure is achieved from simulated data in the presence of realistic noise perturbations, to control the reconstruction error. By way of illustration we have applied our procedure to the Mimas 5:3 density wave. We were able to recover precisely the kinematic parameters from the radio experiment occultation data in most of the propagation region; a preliminary analysis of the pressure-corrected dispersion allowed us to determine new but still uncertain values for the opacity ($K\\simeq 0.02$ cm$^2$/g) and velocity dispersion of ($c_o\\simeq 0.6$ cm/s) in the wave region. Our procedure constitutes the first step in our planned analysis of the density waves of Sa...

  13. Fluid and gyrokinetic modelling of particle transport in plasmas with hollow density profiles

    Science.gov (United States)

    Tegnered, D.; Oberparleiter, M.; Nordman, H.; Strand, P.

    2016-11-01

    Hollow density profiles occur in connection with pellet fuelling and L to H transitions. A positive density gradient could potentially stabilize the turbulence or change the relation between convective and diffusive fluxes, thereby reducing the turbulent transport of particles towards the center, making the fuelling scheme inefficient. In the present work, the particle transport driven by ITG/TE mode turbulence in regions of hollow density profiles is studied by fluid as well as gyrokinetic simulations. The fluid model used, an extended version of the Weiland transport model, Extended Drift Wave Model (EDWM), incorporates an arbitrary number of ion species in a multi-fluid description, and an extended wavelength spectrum. The fluid model, which is fast and hence suitable for use in predictive simulations, is compared to gyrokinetic simulations using the code GENE. Typical tokamak parameters are used based on the Cyclone Base Case. Parameter scans in key plasma parameters like plasma β, R/LT , and magnetic shear are investigated. It is found that β in particular has a stabilizing effect in the negative R/Ln region, both nonlinear GENE and EDWM show a decrease in inward flux for negative R/Ln and a change of direction from inward to outward for positive R/Ln . This might have serious consequences for pellet fuelling of high β plasmas.

  14. Association of lipid profile with bone mineral density in postmenopausal women in Yazd province

    Science.gov (United States)

    Ghadiri-Anari, Akram; Mortezaii-Shoroki, Zahra; Modarresi, Mozhgan; Dehghan, Ali

    2016-01-01

    Background: Low bone mass is a major health problem in postmenopausal women. There is no general agreement regarding relationship between serum level of lipids and bone mineral density. Objective: This study was carried out to investigate the association between lipid profile and bone mineral density (BMD) in postmenopausal women in Yazd, Iran. Materials and Methods: This cross-sectional study was performed on 170 women aged between 50 and 70 years old with menopause for at least one year from Yazd, Iran, between March 2013 to September 2013. Association of lipid profile and BMD were measured in all study participants. Results: Among our participants 73 cases had lumbar osteoporosis, 17 cases had femoral osteoporosis and 80 cases did n’t have osteoporosis. After controlling for body mass index, there were no correlations between serum level of lipids and bone mineral density of femur and lumbar bones. Conclusion: No significant association between serum level of lipids and BMD of femur and lumbar was found in postmenopausal women. PMID:27738662

  15. Density profile in thin films of polybutadiene on silicon oxide substrates: a TOF-NR study.

    Science.gov (United States)

    Hoppe, E Tilo; Sepe, Alessandro; Haese-Seiller, Martin; Moulin, Jean-François; Papadakis, Christine M

    2013-08-27

    We have investigated thin films from fully deuterated polybutadiene (PB-d6) on silicon substrates with the aim of detecting and characterizing a possible interphase in the polymer film near the substrate using time-of-flight neutron reflectometry (TOF-NR). As substrates, thermally oxidized silicon wafers were either used as such or they were coated with triethylethoxysilyl modified 1,2-PB prior to deposition of the PB-d6 film. TOF-NR reveals that, for both substrates, the scattering length density (SLD) of the PB films decreases near the solid interface. The reduction of SLD is converted to an excess fraction of free volume. To further verify the existence of the interphase in PB-d6, we attempt to model the TOF-NR curves with density profiles which do not feature an interphase. These density profiles do not describe the TOF-NR curves adequately. We conclude that, near the solid interface, an interphase having an SLD lower than the bulk of the film is present.

  16. Relativistic self-focusing of intense laser beam in thermal collisionless quantum plasma with ramped density profile

    Science.gov (United States)

    Zare, S.; Yazdani, E.; Rezaee, S.; Anvari, A.; Sadighi-Bonabi, R.

    2015-04-01

    Propagation of a Gaussian x-ray laser beam has been analyzed in collisionless thermal quantum plasma with considering a ramped density profile. In this density profile due to the increase in the plasma density, an earlier and stronger self-focusing effect is noticed where the beam width oscillates with higher frequency and less amplitude. Moreover, the effect of the density profile slope and the initial plasma density on the laser propagation has been studied. It is found that, by increasing the initial density and the ramp slope, the laser beam focuses faster with less oscillation amplitude, smaller laser spot size and more oscillations. Furthermore, a comparison is made among the laser self-focusing in thermal quantum plasma, cold quantum plasma and classical plasma. It is realized that the laser self-focusing in the quantum plasma becomes stronger in comparison with the classical regime.

  17. A simple frequency sweep linearization method for FM density profile reflectometry

    Science.gov (United States)

    Liu, Adi; Hu, Jianqiang; Doyle, Edward; Zhang, Jin; Li, Hong; Zhou, Chu; Zhang, Xiaohui; Wang, Mingyuan; Lan, Tao; Xie, Jinglin; Liu, Wandong; Yu, Changxuan

    2015-11-01

    Frequency modulated, continuous wave (FMCW) reflectometry is widely used to measure the electron density profile on fusion devices. To ensure the output intermediate frequency signal is proportional to the propagation delay time, the frequency sweep should be linearized, especially for reflectometry with sweeping periods of only a few microseconds. We introduce a simple dynamic calibration technique to linearize the frequency sweep based on digital complex demodulation methods, without using a Fourier transform, which would induce a trade-off between frequency and time resolution. The technique is convenient as it can be done in the same conditions as for plasma measurements. The method is in use on the EAST profile reflectometer, and results will be presented. Work was supported by the Natural Science Foundation of China (NSFC) under 11475173, National Magnetic Confinement Fusion Energy Development Program of China under 2013GB106002 and 2014GB109002, and US DOE Grants DE- SC0010424 and DE-SC0010469.

  18. Iterative noise removal from temperature and density profiles in the TJ-II Thomson scattering

    Energy Technology Data Exchange (ETDEWEB)

    Farias, G., E-mail: gonzalo.farias@ucv.cl [Pontificia Universidad Católica de Valparaíso, Av. Brasil 2147, Valparaíso (Chile); Dormido-Canto, S., E-mail: sebas@dia.uned.es [Departamento de Informática y Automática, UNED, 28040 Madrid (Spain); Vega, J., E-mail: jesus.vega@ciemat.es [Asociación EURATOM/CIEMAT para Fusión, Avd. Complutense 22, 28040 Madrid (Spain); Santos, M., E-mail: msantos@ucm.es [Departamento de Arquitectura de Computadores y Automática, Universidad Complutense de Madrid, 28040 Madrid (Spain); Pastor, I., E-mail: ignacio.pastor@ciemat.es [Asociación EURATOM/CIEMAT para Fusión, Avd. Complutense 22, 28040 Madrid (Spain); Fingerhuth, S., E-mail: sebastian.fingerhuth@ucv.cl [Pontificia Universidad Católica de Valparaíso, Av. Brasil 2147, Valparaíso (Chile); Ascencio, J., E-mail: j_ascencio21@hotmail.com [Pontificia Universidad Católica de Valparaíso, Av. Brasil 2147, Valparaíso (Chile)

    2014-05-15

    TJ-II Thomson Scattering diagnostic provides temperature and density profiles of plasma. The CCD camera acquires images that are corrupted with some kind of noise called stray-light. This noise degrades both image contrast and measurement accuracy, which could produce unreliable profiles of the diagnostic. So far, several approaches have been applied in order to decrease the noise in the TJ-II Thomson scattering images. Since the presence of the noise is not global but located in some particular regions of the image, advanced processing techniques are needed. However such methods require of manual fine-tuning of parameters to reach a good performance. In this contribution, an iterative image processing approach is applied in order to reduce the stray light effects in the images of the TJ-II Thomson scattering diagnostic. The proposed solution describes how the noise can be iteratively reduced in the images when a key parameter is automatically adjusted during the iterative process.

  19. Comparison of human glomerulus proteomic profiles obtained from low quantities of samples by different mass spectrometry with the comprehensive database

    Directory of Open Access Journals (Sweden)

    Liu Zan

    2011-08-01

    Full Text Available Abstract Background We have previously constructed an in-depth human glomerulus proteome database from a large amount of sample for understanding renal disease pathogenesis and aiding the biomarker exploration. However, it is usually a challenge for clinical research to get enough tissues for large-scale proteomic characterization. Therefore, in this study, we focused on high-confidence proteomics analysis on small amounts of human glomeruli comparable to those obtained from biopsies using different mass spectrometers and compared these results to the comprehensive database. Results One microgram of human glomerular protein digest was analyzed each on five LC- combined mass spectrometers (LIT-TOF, LTQ-Orbitrap, Q-TOF, LIT and MALDI-TOF/TOF yielding 139, 185, 94, 255 and 108 proteins respectively identified with strict criteria to ensure high confidence (> 99% and low false discovery rate (FDR ( Conclusion This study showed representative human glomerulus proteomic profiles obtained from biopsies through analysis of comparable amounts of samples by different mass spectrometry. Our results implicated that high abundant proteins are more likely to be reproducibly identified in multiple mass spectrometers runs and different mass spectrometers. Furthermore, many podocyte essential proteins such as nephrin, podocin, podocalyxin and synaptopodin were also identified from the small samples in this study. Bioinformatic enrichment analysis results extended our understanding of the major glomerular proteins about their subcellular distributions and functions. The present study indicated that the proteins localized in certain cellular compartments, such as actin cytoskeleton, mitochondrial matrix, cell surface, basolateral plasma membrane, contractile fiber, proteinaceous extracellular matrix and adherens junction, represent high abundant glomerular proteins and these subcellular structures are also highly significantly over-represented in the glomerulus

  20. Near-Infrared Properties of Moderate-Redshift Galaxy Clusters: Luminosity Functions and Density Profiles

    Energy Technology Data Exchange (ETDEWEB)

    Muzzin, Adam; Yee, H.K.C.; /Toronto U., Astron. Dept.; Hall, Patrick B.; /York U., Canada; Ellingson, E.; /Colorado U., CASA; Lin, Huan; /Fermilab

    2006-12-01

    We present K-band imaging for 15 of the Canadian Network for Observational Cosmology (CNOC1) clusters. The extensive spectroscopic dataset available for these clusters allows us to determine the cluster K-band luminosity function and density profile without the need for statistical background subtraction. The luminosity density and number density profiles can be described by NFW models with concentration parameters of c{sub l} = 4.28 {+-} 0.70 and c{sub g} = 4.13 {+-} 0.57 respectively. Comparing these to the dynamical mass analysis of the same clusters shows that the galaxy luminosity and number density profiles are similar to the dark matter profile, and are not less concentrated like in local clusters. The luminosity functions show that the evolution of K. over the redshift range 0.2 < z < 0.5 is consistent with a scenario where the majority of stars in cluster galaxies form at high-redshift (z{sub f} > 1.5) and evolve passively thereafter. The best-fit for the faint-end slope of the luminosity function is {alpha} = -0.84 {+-} 0.08, which indicates that it does not evolve between z = 0 and z = 0.3. Using Principal Component Analysis of the spectra we classify cluster galaxies as either star-forming/recently-star-forming (EM+BAL) or non-star forming (ELL) and compute their respective luminosity functions. The faint-end slope of the ELL luminosity function is much shallower than for the EM+BAL galaxies at z = 0.3, and suggests the number of faint ELL galaxies in clusters decreases by a factor of {approx} 3 from z = 0 to z = 0.3. The redshift evolution of K* for both EM+BAL and ELL types is consistent with a passively evolving stellar population formed at high-redshift. Passive evolution in both classes, as well as the total cluster luminosity function, demonstrates that the bulk of the stellar population in all bright cluster galaxies is formed at high-redshift and subsequent transformations in morphology/color/spectral-type have little effect on the total stellar

  1. Force-free collisionless current sheet models with non-uniform temperature and density profiles

    Science.gov (United States)

    Wilson, F.; Neukirch, T.; Allanson, O.

    2017-09-01

    We present a class of one-dimensional, strictly neutral, Vlasov-Maxwell equilibrium distribution functions for force-free current sheets, with magnetic fields defined in terms of Jacobian elliptic functions, extending the results of Abraham-Shrauner [Phys. Plasmas 20, 102117 (2013)] to allow for non-uniform density and temperature profiles. To achieve this, we use an approach previously applied to the force-free Harris sheet by Kolotkov et al. [Phys. Plasmas 22, 112902 (2015)]. In one limit of the parameters, we recover the model of Kolotkov et al. [Phys. Plasmas 22, 112902 (2015)], while another limit gives a linear force-free field. We discuss conditions on the parameters such that the distribution functions are always positive and give expressions for the pressure, density, temperature, and bulk-flow velocities of the equilibrium, discussing the differences from previous models. We also present some illustrative plots of the distribution function in velocity space.

  2. Real-time identification of the current density profile in the JET Tokamak: method and validation

    CERN Document Server

    Mazon, Didier; Boulbe, Cédric; Faugeras, Blaise; Boboc, A; Brix, M; De Vries, P; Sharapov, S; Zabeo, L

    2009-01-01

    The real-time reconstruction of the plasma magnetic equilibrium in a Tokamak is a key point to access high performance regimes. Indeed, the shape of the plasma current density profile is a direct output of the reconstruction and has a leading effect for reaching a steady-state high performance regime of operation. In this paper we present the methodology followed to identify numerically the plasma current density in a Tokamak and its equilibrium. In order to meet the real-time requirements a C++ software has been developed using the combination of a finite element method, a nonlinear fixed point algorithm associated to a least square optimization procedure. The experimental measurements that enable the identification are the magnetics on the vacuum vessel, the interferometric and polarimetric measurements on several chords and the motional Stark effect. Details are given about the validation of the reconstruction on the JET tokamak, either by comparison with ?off-line' equilibrium codes or real time software ...

  3. Neutral-depletion-induced asymmetric plasma density profile and momentum transport in a helicon thruster

    Science.gov (United States)

    Takahashi, Kazunori; Takao, Yoshinori; Chiba, Aiki; Ando, Akira

    2016-09-01

    Axial momentum lost to a lateral wall of a helicon source is directly measured by using a pendulum force balance, where only the lateral wall is attached to the balance immersed in 60-cm-diam and 1.4-m-long vacuum tank (pumping speed of 300-400 L/s). When operating the source with highly ionized krypton and xenon, the strong density decay along the axis is observed inside the source tube, which seems to be due to the neutral depletion. Under such a condition, a non-negligible loss of the axial momentum to the lateral wall is detected. The presently detected loss of the axial momentum indicates the presence of the ions which are axially accelerated by the electric field in the plasma core and then lost to the lateral wall. Furthermore, the helicon thruster immersed in 1-m-diam and 2-m-long vacuum tank (pumping speed of 4000-5000 L/s) is operated at high rf power up to 5 kW in argon, to demonstrate the neutral-depletion-induced axially asymmetric density profile. Combination between the Langmuir probe and the optical diagnosis indicates that the neutral density at the axial center of the source is reduced to 20% of the initial neutral density. This work is partially supported by grant-in-aid for scientific research (16H04084 and 26247096) from the Japan Society for the Promotion of Science.

  4. Fat characteristics and fatty acid profile of sea cucumbers (Holothuria Scabra obtained from the coasts of the Bushehr province -Iran

    Directory of Open Access Journals (Sweden)

    Najmeh Jadavi

    2015-11-01

    Full Text Available Background: Sea cucumbers are belonging to echinoderms and one of the important members of the food chain in temperate ecosystems and tropical coral reefs. The medicinal and nutritional uses of these invertebrates are primordial and are important as ecological, biological and economic properties. Holothuria Scabra, as one of the most valuable commercial species of sea cucumber in the world, is the dominant species in many Persian Gulf coasts such as the Bushehr province coasts. Conspicuous characteristics such as the use of inexpensive foods in their culture, the rather rapid, easy and low cost growth and reproduction, the possibility of culture with other fish, reduce the organic substrate in pools, the broad tolerance in water factors changes such as salinity and temperature it has selected them to culture.It seems they are containing the significant amounts of nutrients, especially appreciated fatty acids. Therefore, the aims of the current study are determination of total fat content, quality and quantity evaluations of some physicochemical parameters such as acid value (AV, peroxide value (PV, and refractive index (RI as well as, identify the profile of fatty acids in the fat. Materials & Methods: In this study, after collecting the 36 samples of sea cucumbers from the coasts of the bushehr province, sample preparation, and extraction of fat, their fatty acids profile were analyzed using gas chromatography with flame ionization detector (GC-FID. Results: The peroxide and the acid values were 0.62±0.0435 and 0.7553±0.0034. The optical refractive index of the oil was 1467 at 26°C, and total fat was also 2%. Among 19 identified fatty acids obtained from the GC analysis of Holothuria Scabra oil, fatty acids: heneicosanoic acid, linoleic acid, palimitic acid, stearic acid, linoleic acid, and Meristic acid, with respectively amounts of 40.81%, 27.5%, 15.24%, 4.73%, 4.46% and 2.38% had the highest values, and other fatty acids were negligible

  5. Plasma density evolution in plasma opening switch obtained by a time-resolved sensitive He-Ne interferometer

    Science.gov (United States)

    Chen, Lin; Ren, Jing; Guo, Fan; Zhou, LiangJi; Li, Ye; He, An; Jiang, Wei

    2014-03-01

    To understand the formation process of vacuum gap in coaxial microsecond conduction time plasma opening switch (POS), we have made measurements of the line-integrated plasma density during switch operation using a time-resolved sensitive He-Ne interferometer. The conduction current and conduction time in experiments are about 120 kA and 1 μs, respectively. As a result, more than 85% of conduction current has been transferred to an inductive load with rise time of 130 ns. The radial dependence of the density is measured by changing the radial location of the line-of-sight for shots with the same nominal POS parameters. During the conduction phase, the line-integrated plasma density in POS increases at all radial locations over the gun-only case by further ionization of material injected from the guns. The current conduction is observed to cause a radial redistribution of the switch plasma. A vacuum gap forms rapidly in the plasma at 5.5 mm from the center conductor, which is consistent with the location where magnetic pressure is the largest, allowing current to be transferred from the POS to the load.

  6. Tidal stirring of satellites with shallow density profiles prevents them from being too big to fail

    CERN Document Server

    Tomozeiu, Mihai; Quinn, Thomas

    2016-01-01

    The "too big to fail" problem is revisited by studying the tidal evolution of populations of dwarf satellites with different density profiles. The high resolution cosmological $\\rm \\Lambda CDM$ "ErisMod" set of simulations is used. These simulations can model both the stellar and dark matter components of the satellites, and their evolution under the action of the tides of a MW-sized host halo at a force resolution better than 10 pc. The stronger tidal mass loss and re-shaping of the mass distribution induced in satellites with $\\gamma=0.6$ dark matter density distributions, as those resulting from the effect of feedback in hydrodynamical simulations of dwarf galaxy formation, is sufficient to bring the circular velocity profiles in agreement with the kinematics of MW's dSphs. In contrast, in simulations in which the satellites retain cusps at $z=0$ there are several "massive failures" with circular velocities in excess of the observational constraints. Various sources of deviations in the conventionally adop...

  7. Gravitational acceleration and tidal effects in spherical-symmetric density profiles

    CERN Document Server

    Caimmi, R

    2015-01-01

    Pure power-law density profiles, $\\rho(r)\\propto r^{b-3}$, are classified in connection with the following reference cases: (i) isodensity, $b=3$, $\\rho=$ const; (ii) isogravity, $b=2$, $g=$ const; (iii) isothermal, $b=1$, $v=[GM(r)/r]^{1/2}=$ const; (iv) isomass, $b=0$, $M=$ const. A restricted number of different families of density profiles including, in addition, cored power-law, generalized power-law, polytropes, are studied in detail with regard to both one-component and two-component systems. Considerable effort is devoted to the existence of an extremum point (maximum absolute value) in the gravitational acceleration within the matter distribution. Predicted velocity curves are compared to the data inferred from observations. Tidal effects on an inner subsystem are investigated and an application is made to globular clusters within the Galaxy. To this aim, the tidal radius is defined by balancing the opposite gravitational forces from the Galaxy and the selected cluster on a special point of the clust...

  8. Aluminum integral foams with tailored density profile by adapted blowing agents

    Science.gov (United States)

    Hartmann, Johannes; Fiegl, Tobias; Körner, Carolin

    2014-05-01

    The goal of the present work is the variation of the structure of aluminum integral foams regarding the thickness of the integral solid skin as well as the density profile. A modified die casting process, namely integral foam molding, is used in which an aluminum melt and blowing agent particles (magnesium hydride MgH2) are injected in a permanent steel mold. The high solidification rates at the cooled walls of the mold lead to the formation of a solid skin. In the inner region, hydrogen is released by thermal decomposition of MgH2 particles. Thus, the pore formation takes place parallel to the continuing solidification of the melt. The thickness of the solid skin and the density profile of the core strongly depend on the interplay between solidification velocity and kinetics of hydrogen release. By varying the melt and blowing agent properties, the structure of integral foams can be systematically changed to meet the requirements of the desired field of application of the produced component.

  9. Evolution of Density Profiles in High-z Galaxies: Compaction and Quenching Inside-Out

    CERN Document Server

    Tacchella, Sandro; Carollo, C Marcella; Ceverino, Daniel; DeGraf, Colin; Lapiner, Sharon; Mandelker, Nir; Primack, Joel R

    2015-01-01

    Using cosmological simulations, we address the interplay between structure and star formation in high-redshift galaxies via the evolution of surface density profiles. Our sample consists of 26 galaxies evolving in the redshift range $z=7-1$, spanning the stellar mass range $(0.2-6.4)\\times 10^{10}M_\\odot$ at $z=2$. We recover the main trends by stacking the profiles in accordance to their evolution phases. Following a wet compaction event that typically occurs when the stellar mass is $\\sim10^{9.5}~M_{\\odot}$ at $z\\sim2-4$, the gas develops a cusp inside the effective radius, associated with a peak in star-formation rate (SFR). The SFR peak and the associated feedback, in the absence of further gas inflow to the centre, marks the onset of gas depletion from the central 1 kpc, leading to quenching of the central SFR. An extended, star-forming ring that forms by fresh gas during the central quenching process shows as a rising specific SFR (sSFR) profile, which is interpreted as inside-out quenching. Before quen...

  10. Density profiles of galaxy groups and clusters from SDSS galaxy-galaxy weak lensing

    CERN Document Server

    Mandelbaum, R; Cool, R J; Blanton, M; Hirata, C M; Brinkmann, J; Mandelbaum, Rachel; Seljak, Uros; Cool, Richard J.; Blanton, Michael; Hirata, Christopher M.; Brinkmann, Jonathan

    2006-01-01

    We present results of a measurement of the shape of the density profile of galaxy groups and clusters traced by 43 335 Luminous Red Galaxies (LRGs) with spectroscopic redshifts from the Sloan Digital Sky Survey (SDSS). The galaxies are selected such that they are the brightest within a cylindrical aperture, split into two luminosity samples, and modeled as the sum of stellar and dark matter components. We present a detailed investigation of many possible systematic effects that could contaminate our signal and develop methods to remove them, including a detected intrinsic alignment for galaxies within 100 kpc/h of LRGs which we remove using photometric redshift information. The resulting lensing signal is consistent with NFW profile dark matter halos; the SIS profile is ruled out at the 96 (conservatively) and 99.96 per cent confidence level (CL) for the fainter and brighter lens samples (respectively) when we fit using lensing data between 40 kpc/h and 2 Mpc/h with total signal-to-noise of 19 and 25 for the ...

  11. Analysis of cytokine profile and growth factors in platelet-rich plasma obtained by open systems and commercial columns.

    Science.gov (United States)

    Pochini, Alberto de Castro; Antonioli, Eliane; Bucci, Daniella Zanetti; Sardinha, Luiz Roberto; Andreoli, Carlos Vicente; Ferretti, Mario; Ejnisman, Benno; Goldberg, Anna Carla; Cohen, Moisés

    2016-01-01

    To evaluate growth factors and cytokines in samples of platelet-rich plasma obtained by three different centrifugation methods. Peripheral blood of six individuals with no hematological diseases, aged 18 to 68 years, was drawn to obtain platelet-rich plasma, using the open method and commercial columns by Medtronic and Biomet. The products obtained with the different types of centrifugation were submitted to laboratory analysis, including pro-inflammatory cytokines and chemokines by flow cytometry assays, the concentration of fibroblast growth factors-2 (FGF-2) and transforming growth factor-beta1 (TGF-β1). The diverse separation methods generated systematically different profiles regarding number of platelets and leukocytes. The Medtronic system yielded a product with the highest concentration of platelets, and the open method, with the lowest concentration of platelets. The results of cytokine analysis showed that the different types of centrifugation yielded products with high concentrations of interleukin 8, interleukin 1β. The open system resulted in a product with high levels of interleukin 6. Other cytokines and chemokines measured were similar between systems. The product obtained with the open method showed higher levels of TGF-β1 in relation to other systems and low FGF-2 levels. The formed elements, growth factors and cytokines in samples of platelet-rich plasma varied according to the centrifugation technique used. Avaliar fatores de crescimento e citocinas em amostras de plasma rico em plaquetas obtidas por três diferentes métodos de centrifugação. Foi coletado sangue periférico de seis indivíduos, sem doença hematológica, com idades entre 18 e 68 anos, para obtenção de plasma rico em plaquetas, utilizando o método aberto e sistemas comerciais das empresas Medtronic e Biomet. Os produtos obtidos com os diferentes tipos de centrifugação foram submetidos às análises laboratoriais, incluindo citocinas próinflamatórias e quimiocinas

  12. Impact of a hollow density profile on turbulent particle fluxes: Gyrokinetic and fluid simulations

    Science.gov (United States)

    Tegnered, D.; Oberparleiter, M.; Strand, P.; Nordman, H.

    2017-07-01

    Hollow density profiles may occur in connection with pellet fuelling and L to H transitions. A positive density gradient could potentially stabilize the turbulence or change the relation between convective and diffusive fluxes, thereby reducing the turbulent transport of particles towards the center, making the pellet fuelling scheme inefficient. In the present work, the particle transport driven by Ion Temperature Gradient/Trapped Electron (ITG/TE) mode turbulence in hollow density profiles is studied by fluid as well as gyrokinetic simulations. The fluid model used, an extended version of the Weiland transport model, Extended Drift Wave Model (EDWM), incorporates an arbitrary number of ion species in a multi-fluid description and an extended wavelength spectrum. The fluid model, which is fast and hence suitable for use in predictive simulations, is compared to gyrokinetic simulations using the code GENE. Typical tokamak parameters are used based on the Cyclone Base Case. Parameter scans in key plasma parameters like plasma β, R/LT, and magnetic shear are investigated. In addition, the effects of a fast species are studied and global ITG simulations in a simplified physics description are performed in order to investigate nonlocal effects. It is found that β in particular, has a stabilizing effect in the negative R/Ln region. Both nonlinear GENE and EDWM simulations show a decrease in inward flux for negative R/Ln and a change in the direction from inward to outward for positive R/Ln. Moreover, the addition of fast particles was shown to decrease the inward main ion particle flux in the positive gradient region further. This might have serious consequences for pellet fuelling of high β plasmas. Additionally, the heat flux in global ITG turbulence simulations indicates that nonlocal effects can play a different role from usual in connection with pellet fuelling.

  13. Density of Zeros on the Lee-Yang circle obtained from magnetization data of a two-dimensional Ising ferromagnet

    OpenAIRE

    Binek, Ch.

    1998-01-01

    In order to provide an experimental access to the statistical theory of Lee and Yang (1952) the density function g(theta) of zeros on the Lee-Yang circle has been determined for the first time by analyzing isothermal magnetization data, m(H), of the Ising ferromagnet FeCl2 in axial magnetic fields, H, at temperatures 34 < T < 99K. The validity of our approach is demonstrated by the perfect agreement of magnetic specific heat data as calculated from g(theta) and m(H) via Maxwells relation, res...

  14. Monitoring of the mass density profile along the 0° geomagnetic longitude during magnetic storms with the use of ground magnetometers.

    Science.gov (United States)

    Romanova, N.; Stepanova, M. V.; Kozyreva, O. V.; Pilipenko, V.; Zesta, E.

    2015-12-01

    Ground magnetometers offer a very cheap and robust means of globally monitoring the magnetospheric mass density, by determining the ULF field line resonant frequency. ULF waves are almost always present in near-Earth environment and are generated by the solar wind interaction with the terrestrial magnetosphere. These waves from the magnetopause propagate through the magnetosphere. When they encounter a field line that resonates at the same frequency, coupling to the Alfven field line oscillations occurs and the resonance can be detected on the ground at that particular latitude. There are different methods for determining resonant frequencies from ground ULF waves. the density profiles along the 0° geomagnetic longitude were obtained using both the gradient and the amplitude-phase methods for the analysis of the magnetic field data from the magnetometer arrays: SAMBA (South American Meridional B-field Array), MAGDAS and American Antarctic bases (Palmer, WAIS-D). We compared the density profiles during quiet magnetic conditions and during strong magnetic storms (recovery phase). It is shown that in the recovery phase of strong magnetic storms (Dst <-150 nT) profile of the equatorial mass density varies greatly in comparison with the density distribution in quiet days.

  15. A LOFAR census of non-recycled pulsars: average profiles, dispersion measures, flux densities, and spectra

    CERN Document Server

    Bilous, A; Kramer, M; Keane, E; Hessels, J; Stappers, B; Malofeev, V; Sobey, C; Breton, R; Cooper, S; Falcke, H; Karastergiou, A; Michilli, D; Osłowski, S; Sanidas, S; ter Veen, S; van Leeuwen, J; Verbiest, J; Weltevrede, P; Zarka, P; Grießmeier, J -M; Serylak, M; Bell, M; Broderick, J; Eislöffel, J; Markoff, S; Rowlinson, A

    2015-01-01

    We present first results from a LOFAR census of non-recycled pulsars. The census includes almost all such pulsars known (194 sources) at declinations Dec$> 8^\\circ$ and Galactic latitudes |Gb|$> 3^\\circ$, regardless of their expected flux densities and scattering times. Each pulsar was observed contiguously in the frequency range from 110$-$188 MHz and for $\\geq 20$ minutes, recording full-Stokes data. We present the dispersion measures, flux densities, and calibrated total intensity profiles for the 158 pulsars detected in the sample. The median uncertainty in census dispersion measures ($1.5 \\times 10^{-4}$ pc cm$^{-3}$) is ten times smaller, on average, than in the ATNF pulsar catalogue. We combined census flux densities with those in the literature and fitted the resulting broadband spectra with single or broken power-law functions. For 48 census pulsars such fits are being published for the first time. Typically, the choice between single and broken power-laws, as well as the location of the spectral bre...

  16. The Surface Density Profile of the Galactic Disk from the Terminal Velocity Curve

    CERN Document Server

    McGaugh, Stacy S

    2015-01-01

    The mass distribution of the Galactic disk is constructed from the terminal velocity curve and the mass discrepancy-acceleration relation. Mass models numerically quantifying the detailed surface density profiles are tabulated. For $R_0 = 8$ kpc, the models have stellar mass $5 < M_* < 6 \\times 10^{10}$ M$_{\\odot}$, scale length $2.0 \\le R_d \\le 2.9$ kpc, LSR circular velocity $222 \\le \\Theta_0 \\le 233$ km s$^{-1}$, and solar circle stellar surface density $34 \\le \\Sigma_d(R_0) \\le 61$ M$_{\\odot}$ pc$^{-2}$. The present inter-arm location of the solar neighborhood may have a somewhat lower stellar surface density than average for the solar circle. The Milky Way appears to be a normal spiral galaxy that obeys scaling relations like the Tully-Fisher relation, the size-mass relation, and the disk maximality-surface brightness relation. The stellar disk is maximal, and the spiral arms are massive. The bumps and wiggles in the terminal velocity curve correspond to known spiral features (e.g., the Centaurus A...

  17. Radial Density Profile in the SSX Plasma Wind Tunnel using a Double Langmuir Probe

    Science.gov (United States)

    Weinhold, D. L.; Flanagan, K.; Gray, T.; Brown, M. R.

    2011-10-01

    We present preliminary results from a moveable double Langmuir probe in the present plasma wind tunnel configuration of SSX. The probe is designed to measure radial profiles of electron density (ne) and electron temperature (Te) across the midplane with a 1 cm resolution. Line-averaged densities from He-Ne interferometry show densities of 1 - 5 ×1015 cm-3 . In addition to mean values, we will also present electrostatic fluctuations and correlations with magnetic field measurements. The double Langmuir probe also measures local Te. Line-averaged measurements from VUV spectroscopy indicate Te ~ 10 eV . The Langmuir probe stalk diameter measures 6 . 5 mm and tip spacing is 1 . 1 mm . The SSX plasma wind tunnel has dimensions L ≅ 1 m and R = 0 . 08 m . Plasma flow speeds are v >= 50 km / s . The cylindrical copper boundary and probe surfaces are baked and cleaned in a He glow discharge to maintain excellent vacuum and surface conditions. Electrostatic measurements during merging will be presented if available. Work supported by US DOE and CMSO.

  18. Constraints on the halo density profile using HI flaring in the outer Galaxy

    CERN Document Server

    Narayan, C A; Jog, C J

    2005-01-01

    The observed flaring of HI disk in the outer region of galaxies has been used in the past to determine the shape of the dark matter halo. Previous studies based on this concept suggest a slightly oblate halo (axis ratio ~ 0.8) for our Galaxy. We reinvestigate this problem by calculating the HI scaleheight in the outer Galaxy to a larger radial distance, and by studying its dependence on the shape and the density profile of the halo. We find that a simple isothermal infinite halo of any shape- oblate or prolate, is not able to account for the observed flaring. Instead we show that a spherical halo with density falling faster than isothermal halo in the outer region provides a better fit to the observed HI flaring as well as the observed rotation curve of our Galaxy. These halos have about 95% of their mass within a few hundreds of kpc. For R_solar = 8.5 kpc and \\Theta_solar = 220 km/s, the central density and core radius can be constrained to the range \\rho_0 = 0.035 - 0.06 M_sun/pc^3 and R_c = 8 - 10 kpc. Our...

  19. Speckle measurements of density and temperature profiles in a model gas circuit breaker

    Science.gov (United States)

    Stoller, P. C.; Panousis, E.; Carstensen, J.; Doiron, C. B.; Färber, R.

    2015-01-01

    Speckle imaging was used to measure the density and temperature distribution in the arc zone of a model high voltage circuit breaker during the high current phase and under conditions simulating those present during current-zero crossings (current-zero-like arc); the arc was stabilized by a transonic, axial flow of synthetic air. A single probe beam was used; thus, accurate reconstruction was only possible for axially symmetric gas flows and arc channels. The displacement of speckles with respect to a reference image was converted to a line-of-sight integrated deflection angle, which was in turn converted into an axially symmetric refractive index distribution using a multistep process that made use of the inverse Radon transform. The Gladstone-Dale relation, which gives the index of refraction as a function of density, was extended to high temperatures by taking into account dissociation and ionization processes. The temperature and density were determined uniquely by assuming that the pressure distribution in the case of cold gas flow (in the absence of an arc) is not modified significantly by the arc. The electric conductivity distribution was calculated from the temperature profile and compared to measurements of the arc voltage and to previous results published in the literature for similar experimental conditions.

  20. Comparison of Relative Activation Energies Obtained by Density Functional Theory and the Random Phase Approximation for Several Claisen Rearrangements.

    Science.gov (United States)

    Hartley, Madeline K; Vine, Seanna; Walsh, Elizabeth; Avrantinis, Sara; Daub, G William; Cave, Robert J

    2016-03-03

    We investigate several representative density functional theory approaches for the calculation of relative activation energies and free energies of a set of model pericyclic reactions, some of which have been studied experimentally. In particular, we use a standard hybrid functional (B3LYP), the same hybrid functional augmented with a basis set superposition error and dispersion correction, a meta-hybrid functional developed to treat transition states and weak interactions (M06-2X), and the recently implemented random phase approximation (RPA) based on Kohn-Sham orbitals from conventional density functional theory by Furche and co-workers. We apply these methods to calculate relative activation energies and estimated free energies for the amide acetal Claisen rearrangement. We focus on relative activation energies to assess the effects of steric and weak interactions in the various methods and compare with experiment where possible. We also discuss the advantages of using this set of reactions as a test bed for the comparison of treatments of weak interactions. We conclude that all methods yield similar trends in relative reactivity, but the RPA yields results in best agreement with the experimental values.

  1. Endovascular biopsy: Strategy for analyzing gene expression profiles of individual endothelial cells obtained from human vessels(✩).

    Science.gov (United States)

    Sun, Zhengda; Lawson, Devon A; Sinclair, Elizabeth; Wang, Chih-Yang; Lai, Ming-Derg; Hetts, Steven W; Higashida, Randall T; Dowd, Christopher F; Halbach, Van V; Werb, Zena; Su, Hua; Cooke, Daniel L

    2015-09-01

    To develop a strategy of achieving targeted collection of endothelial cells (ECs) by endovascular methods and analyzing the gene expression profiles of collected single ECs. 134 ECs and 37 leukocytes were collected from four patients' intra-iliac artery endovascular guide wires by fluorescence activated cell sorting (FACS) and analyzed by single-cell quantitative RT-PCR for expression profile of 48 genes. Compared to CD45(+) leukocytes, the ECs expressed higher levels (p < 0.05) of EC surface markers used on FACS and other EC related genes. The gene expression profile showed that these isolated ECs fell into two clusters, A and B, that differentially expressed 19 genes related to angiogenesis, inflammation and extracellular matrix remodeling, with cluster B ECs have demonstrating similarities to senescent or aging ECs. Combination of endovascular device sampling, FACS and single-cell quantitative RT-PCR is a feasible method for analyzing EC gene expression profile in vascular lesions.

  2. Dark matter density profiles of the halos embedding early-type galaxies: characterizing halo contraction and dark matter annihilation strength

    CERN Document Server

    Chae, Kyu-Hyun; Frieman, Joshua A; Bernardi, Mariangela

    2012-01-01

    Identifying dark matter and characterizing its distribution in the inner region of halos embedding galaxies are inter-related problems of broad importance. We devise a new procedure of determining dark matter distribution in halos. We first make a self-consistent bivariate statistical match of stellar mass and velocity dispersion with halo mass as demonstrated here for the first time. Then, selecting early-type galaxy-halo systems we perform Jeans dynamical modeling with the aid of observed statistical properties of stellar mass profiles and velocity dispersion profiles. Dark matter density profiles derived specifically using Sloan Digital Sky Survey galaxies and halos from up-to-date cosmological dissipationless simulations deviate significantly from the dissipationless profle of Navarro-Frenk-White or Einasto in terms of inner density slope and/or concentration. From these dark matter profiles we find that dark matter density is enhanced in the inner region of most early-type galactic halos providing an ind...

  3. Measurement of heat load density profile on acceleration grid in MeV-class negative ion accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Hiratsuka, Junichi, E-mail: hiratsuka.junichi@jaea.go.jp; Hanada, Masaya; Kojima, Atsushi; Umeda, Naotaka; Kashiwagi, Mieko; Yoshida, Masafumi; Nishikiori, Ryo; Ichikawa, Masahiro; Watanabe, Kazuhiro; Tobari, Hiroyuki [Japan Atomic Energy Agency, 801-1 Mukoyama, Naka 311-0193 (Japan); Miyamoto, Kenji [Naruto University of Education, 748 Nakashima, Takashima, Naruto-cho, Naruto-shi, Tokushima 772-8502 (Japan)

    2016-02-15

    To understand the physics of the negative ion extraction/acceleration, the heat load density profile on the acceleration grid has been firstly measured in the ITER prototype accelerator where the negative ions are accelerated to 1 MeV with five acceleration stages. In order to clarify the profile, the peripheries around the apertures on the acceleration grid were separated into thermally insulated 34 blocks with thermocouples. The spatial resolution is as low as 3 mm and small enough to measure the tail of the beam profile with a beam diameter of ∼16 mm. It was found that there were two peaks of heat load density around the aperture. These two peaks were also clarified to be caused by the intercepted negative ions and secondary electrons from detailed investigation by changing the beam optics and gas density profile. This is the first experimental result, which is useful to understand the trajectories of these particles.

  4. Determination of CT number and density profile of binderless, pre-treated and tannin-based Rhizophora spp. particleboards using computed tomography imaging and electron density phantom

    Energy Technology Data Exchange (ETDEWEB)

    Yusof, Mohd Fahmi Mohd, E-mail: mfahmi@usm.my; Hamid, Puteri Nor Khatijah Abdul; Tajuddin, Abdul Aziz [School of Physics, Universiti Sains Malaysia, 11800 Penang (Malaysia); Bauk, Sabar [School of Distance Education, Universiti Sains Malaysia, 11800 Penang (Malaysia); Hashim, Rokiah [School of Industrial Technologies, Universiti Sains Malaysia, 11800 Penang (Malaysia)

    2015-04-29

    Plug density phantoms were constructed in accordance to CT density phantom model 062M CIRS using binderless, pre-treated and tannin-based Rhizophora Spp. particleboards. The Rhizophora Spp. plug phantoms were scanned along with the CT density phantom using Siemens Somatom Definition AS CT scanner at three CT energies of 80, 120 and 140 kVp. 15 slices of images with 1.0 mm thickness each were taken from the central axis of CT density phantom for CT number and CT density profile analysis. The values were compared to water substitute plug phantom from the CT density phantom. The tannin-based Rhizophora Spp. gave the nearest value of CT number to water substitute at 80 and 120 kVp CT energies with χ{sup 2} value of 0.011 and 0.014 respectively while the binderless Rhizphora Spp. gave the nearest CT number to water substitute at 140 kVp CT energy with χ{sup 2} value of 0.023. The tannin-based Rhizophora Spp. gave the nearest CT density profile to water substitute at all CT energies. This study indicated the suitability of Rhizophora Spp. particleboard as phantom material for the use in CT imaging studies.

  5. Difference between bulk and thin film densities of metal oxide and fluoride films studied by NRA depth profiling techniques

    CERN Document Server

    Coban, A; Durrani, S A

    2002-01-01

    Nuclear reaction analysis techniques have been used to study the difference between bulk and thin film densities of different dielectric (WO sub 3 , MgF sub 2 , NdF sub 3 , LaF sub 3 and ThF sub 4) thin films. Thicknesses of the films were measured by optical methods. The sup 1 sup 8 O(p,alpha) sup 1 sup 5 N reaction was used at 730 keV to profile WO sub 3 prepared with different thicknesses on a tantalum backing by thermal evaporation of natural WO sub 3. We have also successfully tested the sup 1 sup 8 O(p,alpha) sup 1 sup 5 N reaction at the 629 keV (GAMMA=2.1 keV) resonance for the same purpose. Excitation function measurement of the reaction was performed around the resonant energy at a detection angle of 150 deg. . In order to obtain the oxygen profiles of the thin films non-resonant part of the excitation function was deconvoluted using the known cross-section data of the reaction. Also, we studied different films of MgF sub 2 , NdF sub 3 , LaF sub 3 and ThF sub 4 using the 483.85 keV resonance in the ...

  6. NUMERICAL SOLUTION FOR THE POTENTIAL AND DENSITY PROFILE OF A THERMAL EQUILIBRIUM SHEET BEAM

    Energy Technology Data Exchange (ETDEWEB)

    Lund, S M; Bazouin, G

    2011-03-29

    In a recent paper, S. M. Lund, A. Friedman, and G. Bazouin, Sheet beam model for intense space-charge: with application to Debye screening and the distribution of particle oscillation frequencies in a thermal equilibrium beam, in press, Phys. Rev. Special Topics - Accel. and Beams (2011), a 1D sheet beam model was extensively analyzed. In this complementary paper, we present details of a numerical procedure developed to construct the self-consistent electrostatic potential and density profile of a thermal equilibrium sheet beam distribution. This procedure effectively circumvents pathologies which can prevent use of standard numerical integration techniques when space-charge intensity is high. The procedure employs transformations and is straightforward to implement with standard numerical methods and produces accurate solutions which can be applied to thermal equilibria with arbitrarily strong space-charge intensity up to the applied focusing limit.

  7. NUMERICAL SOLUTION FOR THE POTENTIAL AND DENSITY PROFILE OF A THERMAL EQUILIBRIUM SHEET BEAM

    Energy Technology Data Exchange (ETDEWEB)

    Bazouin, Steven M. Lund, Guillaume; Bazouin, Guillaume

    2011-04-01

    In a recent paper, S. M. Lund, A. Friedman, and G. Bazouin, Sheet beam model for intense space-charge: with application to Debye screening and the distribution of particle oscillation frequencies in a thermal equilibrium beam, in press, Phys. Rev. Special Topics - Accel. and Beams (2011), a 1D sheet beam model was extensively analyzed. In this complementary paper, we present details of a numerical procedure developed to construct the self-consistent electrostatic potential and density profile of a thermal equilibrium sheet beam distribution. This procedure effectively circumvents pathologies which can prevent use of standard numerical integration techniques when space-charge intensity is high. The procedure employs transformations and is straightforward to implement with standard numerical methods and produces accurate solutions which can be applied to thermal equilibria with arbitrarily strong space-charge intensity up to the applied focusing limit.

  8. The late-type stellar density profile in the Galactic Center: A statistical approach

    CERN Document Server

    Chappell, Samantha N; Do, Tuan; Martinez, Gregory D; Yelda, Sylvana; Sitarski, Breann N; Lu, Jessica R; Morris, Mark R

    2016-01-01

    The late-type stellar population in the Galactic Center was first predicted to reside in a dynamically relaxed cusp (power law slope ranging from 3/2 to 7/4). However, observations - which rely on models to correct for projection effects - have suggested a flat distribution instead. The need for this correction is due to the lack of information regarding the line-of-sight distances. With a two decade long baseline in astrometric measurements, we are now able to measure significant projected radial accelerations, six of which are newly reported here, that directly constrain line-of-sight distances. Here we present a statistical approach to take advantage of this information and more accurately constrain the shape of the radial density profile of the late-type stellar population in the Galactic Center.

  9. Effect of Control Blade History, and Axial Coolant Density and Burnup Profiles on BWR Burnup Credit

    Energy Technology Data Exchange (ETDEWEB)

    Ade, Brian J [ORNL; Marshall, William BJ J [ORNL; Martinez-Gonzalez, Jesus S [ORNL

    2015-05-01

    Oak Ridge National Laboratory (ORNL) and the US Nuclear Regulatory Commission (NRC) have initiated a multiyear project to investigate the application of burnup credit (BUC) for boiling water reactor (BWR) fuel in storage and transportation systems (often referred to as casks) and spent fuel pools (SFPs). This work is divided into two main phases. The first phase investigated the applicability of peak reactivity methods currently used in SFPs to transportation and storage casks and the validation of reactivity calculations and spent fuel compositions within these methods. The second phase focuses on extending BUC beyond peak reactivity. This paper documents the analysis of the effects of control blade insertion history, and moderator density and burnup axial profiles for extended BWR BUC.

  10. Whittaker functions in beam driven plasma wakefield acceleration for a plasma with a parabolic density profile

    Energy Technology Data Exchange (ETDEWEB)

    Golian, Y.; Dorranian, D., E-mail: d.dorranian@gmail.com [Laser Laboratory, Plasma Physics Research Center, Science and Research Branch, Islamic Azad University, Tehran (Iran, Islamic Republic of); Aslaninejad, M., E-mail: m.aslaninejad@ipm.ir [Institute for Research in Fundamental Sciences (IPM), School of Particles and Accelerators, P.O. Box 19395-5531, Tehran (Iran, Islamic Republic of)

    2016-01-15

    A model for the interaction of charged particle beams and plasma for a linear wakefield generation in a parabolic plasma channel is presented. The density profile has the maximum on the axis. A Gaussian proton beam is employed to excite the plasma wakefield in the channel. We have built a thorough analytical model and solved the governing equations for the wakefield acceleration of a charged particle beam. The longitudinal and radial wakefields are expressed by Whittaker functions, and for certain parameters of plasma and the beam, their behaviours in longitudinal and radial directions are investigated. It is observed that the radial electric field generated by the bunch increases with the distance behind the bunch.

  11. Whittaker functions in beam driven plasma wakefield acceleration for a plasma with a parabolic density profile

    Science.gov (United States)

    Golian, Y.; Aslaninejad, M.; Dorranian, D.

    2016-01-01

    A model for the interaction of charged particle beams and plasma for a linear wakefield generation in a parabolic plasma channel is presented. The density profile has the maximum on the axis. A Gaussian proton beam is employed to excite the plasma wakefield in the channel. We have built a thorough analytical model and solved the governing equations for the wakefield acceleration of a charged particle beam. The longitudinal and radial wakefields are expressed by Whittaker functions, and for certain parameters of plasma and the beam, their behaviours in longitudinal and radial directions are investigated. It is observed that the radial electric field generated by the bunch increases with the distance behind the bunch.

  12. Physicochemical and dissolution profile characterization of pellets containing different binders obtained by the extrusion-spheronization process

    Directory of Open Access Journals (Sweden)

    Michele Georges Issa

    2012-09-01

    Full Text Available With the purpose of evaluating the behavior of different polymers employed as binders in small-diameter pellets for oral administration, we prepared formulations containing paracetamol and one of the following polymers: PVP, PEG 1500, hydroxypropylmethylcellulose and methylcellulose, and we evaluated their different binding properties. The pellets were obtained by the extrusion/spheronization process and were subsequently subjected to fluid bed drying. In order to assess drug delivery, the United States Pharmacopeia (USP apparatus 3 (Bio-Dis was employed, in conjunction with the method described by the same pharmacopeia for the dissolution of paracetamol tablets (apparatus 1. The pellets were also evaluated for granulometry, friability, true density and drug content. The results indicate that the different binders used are capable of affecting production in different ways, and some of the physicochemical characteristics of the pellets, as well as the dissolution test, revealed that the formulations acted like immediate-release products. The pellets obtained presented favorable release characteristics for orally disintegrating tablets. USP apparatus 3 seems to be more adequate for discriminating among formulations than the basket method.Com a finalidade de se avaliar o comportamento de diferentes polímeros empregados como aglutinantes em pellets de pequeno diâmetro para uso oral foram preparadas formulações contendo paracetamol e um dos seguintes polímeros: PVP, PEG 1500, hidroxipropilmetilcelulose e metilcelulose por apresentarem diferentes propriedades aglutinantes. Os pellets foram obtidos pelo processo de extrusão/esferonização e secagem em leito fluidizado. Para avaliar a liberação do fármaco, empregou-se o método 3 da Farmacopeia Americana, também conhecido como Bio-Dis e o método preconizado pela mesma farmacopeia para comprimidos de paracetamol. Os pellets foram avaliados, ainda, com relação à granulometria, friabilidade

  13. Tidal Disruption of Milky Way Satellites with Shallow Dark Matter Density Profiles

    Directory of Open Access Journals (Sweden)

    Ewa L. Łokas

    2016-11-01

    Full Text Available Dwarf galaxies of the Local Group provide unique possibilities to test current theories of structure formation. Their number and properties have put the broadly accepted cold dark matter model into question, posing a few problems. These problems now seem close to resolution due to the improved treatment of baryonic processes in dwarf galaxy simulations which now predict cored rather than cuspy dark matter profiles in isolated dwarfs with important consequences for their subsequent environmental evolution. Using N-body simulations, we study the evolution of a disky dwarf galaxy with such a shallow dark matter profile on a typical orbit around the Milky Way. The dwarf survives the first pericenter passage but is disrupted after the second due to tidal forces from the host. We discuss the evolution of the dwarf’s properties in time prior to and at the time of disruption. We demonstrate that the dissolution occurs on a rather short timescale as the dwarf expands from a spheroid into a stream with non-zero mean radial velocity. We point out that the properties of the dwarf at the time of disruption may be difficult to distinguish from bound configurations, such as tidally induced bars, both in terms of surface density and line-of-sight kinematics.

  14. Modelling the stellar soft-photon energy density profile of globular clusters

    CERN Document Server

    Prinsloo, P L; Buesching, I; Kopp, A

    2013-01-01

    Recent observations by e.g. Fermi Large Area Telescope (LAT) and the High Energy Stereoscopic System (H.E.S.S.) have revealed globular clusters (GC) to be sources of high-energy (HE) and very-high-energy (VHE) gamma rays. It has been suggested that the presence of large numbers of millisecond pulsars (MSPs) within these clusters may be either directly responsible for these gamma-ray fluxes through emission of pulsed curvature radiation, or indirectly through the injection of relativistic leptons into the cluster. These relativistic particles are plausibly re-accelerated in shocks, created by the collision of stellar winds, before interacting with the soft-photon radiation field set up by the stellar population of the host cluster. Inverse Compton (IC) scattering then produces gamma radiation in the TeV band. In order to calculate the IC spectrum, an accurate profile for the energy density of the soft-photon field is required. We construct such a profile by deriving a radially-dependent expression for the stel...

  15. A "Universal" Density Profile for the Outer Stellar Halos of Galaxies

    CERN Document Server

    Remus, Rhea-Silvia; Dolag, Klaus

    2016-01-01

    The outer stellar halos of galaxies contain vital information about the formation history of galaxies, since the relaxation timescales in the outskirts are long enough to keep the memory, while the information about individual formation events in the central parts has long been lost due to mixing, star formation and relaxation. To unveil some of the information encoded in these faint outer halo regions, we study the stellar outskirts of galaxies selected from a fully hydrodynamical high resolution cosmological simulation, called Magneticum. We find that the density profiles of the outer stellar halos of galaxies over a broad mass range can be well described by an Einasto profile. For a fixed total mass range, the free parameters of the Einasto fits are closely correlated. Galaxies which had more (dry) merger events tend to have lesser curved outer stellar halos, however, we find no indication that the amount of curvature is correlated with galaxy morphology. The Einasto-like shape of the outer stellar halo de...

  16. Density Profiles, Energy, and Oscillation Strength of a Quantum Dot in Two Dimensions with a Harmonic Oscillator External Potential using an Orbital-free Energy Functional Based on Thomas–Fermi Theory

    Directory of Open Access Journals (Sweden)

    Suhufa Alfarisa

    2016-03-01

    Full Text Available This research aims i to determine the density profile and calculate the ground state energy of a quantum dot in two dimensions (2D with a harmonic oscillator potential using orbital-free density functional theory, and ii to understand the effect of the harmonic oscillator potential strength on the electron density profiles in the quantum dot. This study determines the total energy functional of the quantum dot that is a functional of the density that depends only on spatial variables. The total energy functional consists of three terms. The first term is the kinetic energy functional, which is the Thomas–Fermi approximation in this case. The second term is the external potential. The harmonic oscillator potential is used in this study. The last term is the electron–electron interactions described by the Coulomb interaction. The functional is formally solved to obtain the electron density as a function of spatial variables. This equation cannot be solved analytically, and thus a numerical method is used to determine the profile of the electron density. Using the electron density profiles, the ground state energy of the quantum dot in 2D can be calculated. The ground state energies obtained are 2.464, 22.26, 90.1957, 252.437, and 496.658 au for 2, 6, 12, 20, and 56 electrons, respectively. The highest electron density is localized close to the middle of the quantum dot. The density profiles decrease with the increasing distance, and the lowest density is at the edge of the quantum dot. Generally, increasing the harmonic oscillator potential strength reduces the density profiles around the center of the quantum dot.

  17. The Initial Mass Function and the Surface Density Profile of NGC 6231

    CERN Document Server

    Sung, Hwankyung; Bessell, M S

    2012-01-01

    We have performed new wide-field photometry of the young open cluster NGC 6231 to study the shape of the initial mass function (IMF) and mass segregation. We also investigated the reddening law toward NGC 6231 from optical to mid-infrared color excess ratios, and found that the total-to-selective extinction ratio is Rv = 3.2, which is very close to the normal value. But many early-type stars in the cluster center show large color excess ratios. We derived the surface density profiles of four member groups, and found that they reach the surface density of field stars at about 10', regardless of stellar mass. The IMF of NGC 6231 is derived for the mass range 0.8 -- 45 Msun. The slope of the IMF of NGC 6231 (Gamma = -1.1 +/- 0.1) is slightly shallower than the canonical value, but the difference is marginal. In addition, the mass function varies systematically, and is a strong function of radius - it is is very shallow at the center, and very steep at the outer ring suggesting the cluster is mass segregated. We ...

  18. Obtaining Good Performance With Triple-ζ-Type Basis Sets in Double-Hybrid Density Functional Theory Procedures.

    Science.gov (United States)

    Chan, Bun; Radom, Leo

    2011-09-13

    A variety of combinations of B-LYP-based double-hybrid density functional theory (DHDFT) procedures and basis sets have been examined. A general observation is that the optimal combination of exchange contributions is in the proximity of 30% Becke 1988 (B88) exchange and 70% Hartree-Fock (HF) exchange, while for the correlation contributions, the use of independently optimized spin-component-scaled Møller-Plesset second-order perturbation theory (SCS-MP2) parameters (MP2OS and MP2SS) is beneficial. The triple-ζ Dunning aug'-cc-pVTZ+d and Pople 6-311+G(3df,2p)+d basis sets are found to be cost-effective for DHDFT methods. As a result, we have formulated the DuT-D3 DHDFT procedure, which employs the aug'-cc-pVTZ+d basis set and includes 30% B88 and 70% HF exchange energies, 59% LYP, 47% MP2OS, and 36% MP2SS correlation energies, and a D3 dispersion correction with the parameters s6 = 0.5, sr,6 = 1.569, and s8 = 0.35. Likewise, the PoT-D3 DHDFT procedure was formulated with the 6-311+G(3df,2p)+d basis set and has 32% B88 and 68% HF exchange energies, 63% LYP, 46% MP2OS, and 27% MP2SS correlation energies, and the D3 parameters s6 = 0.5, sr,6 = 1.569, and s8 = 0.30. Testing using the large E3 set of 740 energies demonstrates the robustness of these methods. Further comparisons show that the performance of these methods, particularly DuT-D3, compares favorably with the previously reported DSD-B-LYP and DSD-B-LYP-D3 methods used in conjunction with quadruple-ζ aug'-pc3+d and aug'-def2-QZVP basis sets but at lower computational expense. The previously reported ωB97X-(LP)/6-311++G(3df,3pd) procedure also performs very well. Our findings highlight the cost-effectiveness of appropriate- and moderate-sized triple-ζ basis sets in the application of DHDFT procedures.

  19. Resampling soil profiles can constrain large-scale changes in the C cycle: obtaining robust information from radiocarbon measurements

    Science.gov (United States)

    Baisden, W. T.; Prior, C.; Lambie, S.; Tate, K.; Bruhn, F.; Parfitt, R.; Schipper, L.; Wilde, R. H.; Ross, C.

    2006-12-01

    Soil organic matter contains more C than terrestrial biomass and atmospheric CO2 combined, and reacts to climate and land-use change on timescales requiring long-term experiments or monitoring. The direction and uncertainty of soil C stock changes has been difficult to predict and incorporate in decision support tools for climate change policies. Moreover, standardization of approaches has been difficult because historic methods of soil sampling have varied regionally, nationally and temporally. The most common and uniform type of historic sampling is soil profiles, which have commonly been collected, described and archived in the course of both soil survey studies and research. Resampling soil profiles has considerable utility in carbon monitoring and in parameterizing models to understand the ecosystem responses to global change. Recent work spanning seven soil orders in New Zealand's grazed pastures has shown that, averaged over approximately 20 years, 31 soil profiles lost 106 g C m-2 y-1 (p=0.01) and 9.1 g N m{^-2} y-1 (p=0.002). These losses are unexpected and appear to extend well below the upper 30 cm of soil. Following on these recent results, additional advantages of resampling soil profiles can be emphasized. One of the most powerful applications afforded by resampling archived soils is the use of the pulse label of radiocarbon injected into the atmosphere by thermonuclear weapons testing circa 1963 as a tracer of soil carbon dynamics. This approach allows estimation of the proportion of soil C that is `passive' or `inert' and therefore unlikely to respond to global change. Evaluation of resampled soil horizons in a New Zealand soil chronosequence confirms that the approach yields consistent values for the proportion of `passive' soil C, reaching 25% of surface horizon soil C over 12,000 years. Across whole profiles, radiocarbon data suggest that the proportion of `passive' C in New Zealand grassland soil can be less than 40% of total soil C. Below 30 cm

  20. Optimal Density Profile of the Plasma Layer Shielded by a Conducting Surface for the Absorption of Electromagnetic Waves

    Institute of Scientific and Technical Information of China (English)

    王舸; 曹金祥; 宋法伦

    2003-01-01

    Based on the Born approximation, we reduce the approximate analysis solution to the normal and oblique incident electromagnetic wave scattering from the weakly ionized plasma layer shielded by a conducting surface. The solution is closely related to the density profile of the plasma layer. Employing the self-consistent base function, we yield the optimal density profile for the nonuniform plasma layer with the frequencies of incident electromagnetic waves ranging from 4-10 GHz. Numerical studies illustrate the optimal density profile can "survive" wide ranges of the plasma parameters. Different from the validity condition for the Wenzell-Kramers-Brillouin-Jeffreys (WKBJ) approximation, the Born approximation is feasible even if the scale length is smaller than the wavelength.Therefore, the Born approximation is universal against the scattering problem from the weakly ionized plasma.

  1. A Microwave Radiometric Method to Obtain the Average Path Profile of Atmospheric Temperature and Humidity Structure Parameters and Its Application to Optical Propagation System Assessment

    Science.gov (United States)

    Manning, Robert M.; Vyhnalek, Brian E.

    2015-01-01

    The values of the key atmospheric propagation parameters Ct2, Cq2, and Ctq are highly dependent upon the vertical height within the atmosphere thus making it necessary to specify profiles of these values along the atmospheric propagation path. The remote sensing method suggested and described in this work makes use of a rapidly integrating microwave profiling radiometer to capture profiles of temperature and humidity through the atmosphere. The integration times of currently available profiling radiometers are such that they are approaching the temporal intervals over which one can possibly make meaningful assessments of these key atmospheric parameters. Since these parameters are fundamental to all propagation conditions, they can be used to obtain Cn2 profiles for any frequency, including those for an optical propagation path. In this case the important performance parameters of the prevailing isoplanatic angle and Greenwood frequency can be obtained. The integration times are such that Kolmogorov turbulence theory and the Taylor frozen-flow hypothesis must be transcended. Appropriate modifications to these classical approaches are derived from first principles and an expression for the structure functions are obtained. The theory is then applied to an experimental scenario and shows very good results.

  2. Relationship between habitat, densities and metabolic profile in brown hares (Lepus europaeus Pallas

    Directory of Open Access Journals (Sweden)

    Marco Bagliacca

    2010-01-01

    Full Text Available Some habitat traits and haematic parameters were studied to understand the relationships between the hare densities, habitat characteristics and physiological and nutritional condition of the animals. A total of 33 protected areas, reserved for wild game reproduction, located in the Province of Florence (Central Italy, were monitored during a 2-year period. In each protected area the hares were submitted to census. The habitat features of the protected areas were studied and the following parameters were categorised: altitude; cleared-land/total-land ratio; main exposure; main ground composition; water availability; main slope; anthropogenic presence; predator presence; wooded borders; presence of trees and shrubs; surveillance against hunting; demographic predator control; kind of cultivation; unharvested crops for game. After the census the hares were captured for translocation outside in “free” hunting areas. During capture the hares were put in darkened, wooden capture-boxes and remained inside for a variable period of time (10min to 3h. A sample of 3 to 7 hares, captured per year and per each protected area, were removed from the boxes (physically restrained, with covered eyes for blood sample collection, sex, age and live weight determination. The following analyses were performed on frozen plasma samples: ALanine aminoTransferase (ALT, ASpartate aminoTransferase (AST, glucose, cholesterol, Blood Urea Nitrogen (BUN, Ca, P, Mg, Na, K, and Cl concentrations. The relationship between hare density and habitat characteristics was analysed by single regressions analysis. Then the habitat characteristics were subjected to multivariate analysis in relationship to hare body condition. The haematic parameters were analysed by least square means considering habitat traits, animal density, age and sex, as main categorical factors, interaction sex*age, and “pregnant and non-reproducing” nested within sex. Results showed that the highest density

  3. Direct evaluation of the position dependent diffusion coefficient and persistence time from the equilibrium density profile in anisotropic fluids.

    Science.gov (United States)

    Olivares-Rivas, Wilmer; Colmenares, Pedro J; López, Floralba

    2013-08-21

    We derive expressions for the transverse diffusion coefficient D(z) and the average persistence time τ(z; L) within a layer of width L, for particles of a non-homogeneous fluid enclosed in a planar nanopore. The method allows the direct evaluation of these position-dependent dynamical quantities from the equilibrium local particle density profile. We use results for the density and persistence time profiles from the virtual layer molecular dynamics method to numerically assess the significance of the Smoluchowski approximation.

  4. X-ray scattering study of pike olfactory nerve: intensity of the axonal membrane, solution of the phase problem and electron density profile.

    Science.gov (United States)

    Luzzati, Vittorio; Vachette, Patrice; Benoit, Evelyne; Charpentier, Gilles

    2004-10-08

    Synchrotron radiation X-ray scattering experiments were performed on unmyelinated pike olfactory nerves. The difference between the meridional and the equatorial traces of the 2-D spectra yielded the 1-D equatorial intensity of the macromolecular components oriented with respect to the nerve: axonal membranes, microtubules and other cytoskeletal filaments. These 1-D spectra display a diffuse band typical of bilayer membranes and, at small s, a few sharper bands reminiscent of microtubules. All the spectra merge at large s. The intensity of the axonal membrane was determined via a noise analysis of the nerve-dependent spectra, involving also the notion that the thickness of the membrane is finite. The shape of the intensity function indicated that the electron density profile is not centrosymmetric. The knowledge of intensity and thickness paved the way to the electron density profile via an ab initio solution of the phase problem. An iterative procedure was adopted: (i) choose the lattice D of a 1-D pseudo crystal, interpolate the intensity at the points sh = h/D, adopt an arbitrary set of initial phases and compute the profile; (ii) determine the phases corresponding to this profile truncated by the thickness D/2; (iii) repeat the operation with the updated phases until a stable result is obtained. This iterative procedure was carried out for different D-values, starting in each case from randomly generated phases: stable results were obtained in less than 10,000 iterations. Most importantly, for D in the vicinity of 200 A, the overwhelming majority of the profiles were congruent with each other. These profiles were strongly asymmetric and otherwise typical of biological membranes.

  5. On the energy distribution profile of interface states obtained by taking into account of series resistance in Al/TiO{sub 2}/p-Si (MIS) structures

    Energy Technology Data Exchange (ETDEWEB)

    Pakma, O., E-mail: osman@pakma.co [Department of Physics, Faculty of Sciences and Arts, Batman University, Batman (Turkey); Serin, N.; Serin, T. [Department of Engineering Physics, Faculty of Engineering, Ankara University, 06100 Tandogan, Ankara (Turkey); Altindal, S. [Physics Department, Faculty of Arts and Sciences, Gazi University, Teknikokullar, 06500 Ankara (Turkey)

    2011-02-15

    The energy distribution profile of the interface states (N{sub ss}) of Al/TiO{sub 2}/p-Si (MIS) structures prepared using the sol-gel method was obtained from the forward bias current-voltage (I-V) characteristics by taking into account both the bias dependence of the effective barrier height ({phi}{sub e}) and series resistance (R{sub s}) at room temperature. The main electrical parameters of the MIS structure such as ideality factor (n), zero-bias barrier height ({phi}{sub b0}) and average series resistance values were found to be 1.69, 0.519 eV and 659 {Omega}, respectively. This high value of n was attributed to the presence of an interfacial insulator layer at the Al/p-Si interface and the density of interface states (N{sub ss}) localized at the Si/TiO{sub 2} interface. The values of N{sub ss} localized at the Si/TiO{sub 2} interface were found with and without the R{sub s} at 0.25-E{sub v} in the range between 8.4x10{sup 13} and 4.9x10{sup 13} eV{sup -1} cm{sup -2}. In addition, the frequency dependence of capacitance-voltage (C-V) and conductance-voltage (G/{omega}-V) characteristics of the structures have been investigated by taking into account the effect of N{sub ss} and R{sub s} at room temperature. It can be found out that the measured C and G/{omega} are strongly dependent on bias voltage and frequency. -- Research highlights: {yields}We successfully fabricated Al/TiO{sub 2}/p-Si device with interlayer by a sol-gel method. The facts: (i) that the technology of the fabrication of a Al/TiO{sub 2}/p-Si MIS structure much simpler and economical than that for the Si p-n junction and (b) the main advantages of TiO{sub 2} films are low densities of the surface states when compared to SiO{sub 2}.

  6. Analysis of plasma equilibrium based on orbit-driven current density profile in steady-state plasma on QUEST

    Energy Technology Data Exchange (ETDEWEB)

    Nakamura, K., E-mail: nakamura@triam.kyushu-u.ac.jp [RIAM, Kyushu University, Kasuga 816-8580 (Japan); Alam, M.M. [IGSES, Kyushu University, Kasuga 816-8580 (Japan); Jiang, Y.Z. [Tsinghua University, Beijing 100084 (China); Mitarai, O. [Tokai University, Kumamoto 862-8652 (Japan); Kurihara, K.; Kawamata, Y.; Sueoka, M.; Takechi, M. [Japan Atomic Energy Agency, Naka 311-0193 (Japan); Hasegawa, M.; Tokunaga, K.; Araki, K.; Zushi, H.; Hanada, K.; Fujisawa, A.; Idei, H.; Nagashima, Y.; Kawasaki, S.; Nakashima, H.; Higashijima, A.; Nagata, T. [RIAM, Kyushu University, Kasuga 816-8580 (Japan); and others

    2016-11-01

    Highlights: • High energy particle guiding center orbit is calculated as a contour plot of conserved variable. • Current density profile is analyzed based on the orbit-driven current. • Plasma equilibrium is reconstructed by considering the hollow current profile. - Abstract: In the present RF-driven (ECCD) steady-state plasma on QUEST (B{sub t} = 0.25 T, R = 0.68 m, a = 0.40 m), plasma current seems to flow in the open magnetic surface outside of the closed magnetic surface in the low-field region according to plasma current fitting (PCF) method. We consider that the current in the open magnetic surface is due to orbit-driven current by high-energy particles in RF-driven plasma. So based on the analysis of current density profile based on the orbit-driven current, plasma equilibrium is to be calculated. We calculated high energy particles guiding center orbits as a contour plot of conserved variable in Hamiltonian formulation and considered particles initial position with different levels of energy and pitch angles that satisfy resonance condition. Then the profile of orbit-driven current is estimated by multiplying the particle density on the resonance surface and the velocity on the orbits. This analysis shows negative current near the magnetic axis and hollow current profile is expected even if pressure driven current is considered. Considering the hollow current profile shifted toward the low-field region, the equilibrium is fitted by J-EFIT coded by MATLAB.

  7. Spatial profiles of interelectrode electron density in direct current superposed dual-frequency capacitively coupled plasmas

    Science.gov (United States)

    Ohya, Yoshinobu; Ishikawa, Kenji; Komuro, Tatsuya; Yamaguchi, Tsuyoshi; Takeda, Keigo; Kondo, Hiroki; Sekine, Makoto; Hori, Masaru

    2017-04-01

    We present experimentally determined spatial profiles of the interelectrode electron density (n e) in dual-frequency capacitively coupled plasmas in which the negative direct current (dc) bias voltage (V dc) is superposed; in the experiment, 13 MHz (P low) was applied to the lower electrode and 60 MHz (P high) to the upper electrode. The bulk n e increased substantially with increases in the external power, P high, P low, and with increases in V dc. When P low was insufficient, the bulk n e decreased as the V dc bias increased. The bulk n e increased due to its dependence on V dc, especially for |V dc|  >  500 V. This may correspond to the sheath voltages (V s) of the lower electrode. The n e values in front of the upper electrode were coupled with the V dc: the V dc dependence first decreased and then increased. The dc currents (I dc) of the upper electrode were collected when a large P low was applied. The value of I dc at the threshold value of V dc  ≈  V s (e.g.  ‑500 V) increased with an increase in n e. When |V dc| exceeded the threshold, the spatial n e profile and the I dc dependence were changed relative to the electrical characteristics of the dc superposition; this led to a change in the location of the maximum n e, the width of the area of n e depletion in front of the electrodes, and a transition in the electron heating modes.

  8. Influence of DNA extraction on oral microbial profiles obtained via 16S rRNA gene sequencing

    Directory of Open Access Journals (Sweden)

    Loreto Abusleme

    2014-04-01

    Full Text Available Background and objective: The advent of next-generation sequencing has significantly facilitated characterization of the oral microbiome. Despite great efforts in streamlining the processes of sequencing and data curation, upstream steps required for amplicon library generation could still influence 16S rRNA gene-based microbial profiles. Among upstream processes, DNA extraction is a critical step that could represent a great source of bias. Accounting for bias introduced by extraction procedures is important when comparing studies that use different methods. Identifying the method that best portrays communities is also desirable. Accordingly, the aim of this study was to evaluate bias introduced by different DNA extraction procedures on oral microbiome profiles. Design: Four DNA extraction methods were tested on mock communities consisting of seven representative oral bacteria. Additionally, supragingival plaque samples were collected from seven individuals and divided equally to test two commonly used DNA extraction procedures. Amplicon libraries of the 16S rRNA gene were generated and sequenced via 454-pyrosequencing. Results: Evaluation of mock communities revealed that DNA yield and bacterial species representation varied with DNA extraction methods. Despite producing the lowest yield of DNA, a method that included bead beating was the only protocol capable of detecting all seven species in the mock community. Comparison of the performance of two commonly used methods (crude lysis and a chemical/enzymatic lysis+column-based DNA isolation on plaque samples showed no effect of extraction protocols on taxa prevalence but global community structure and relative abundance of individual taxa were affected. At the phylum level, the latter method improved the recovery of Actinobacteria, Bacteroidetes, and Spirochaetes over crude lysis. Conclusion: DNA extraction distorts microbial profiles in simulated and clinical oral samples, reinforcing the

  9. Influence of DNA extraction on oral microbial profiles obtained via 16S rRNA gene sequencing.

    Science.gov (United States)

    Abusleme, Loreto; Hong, Bo-Young; Dupuy, Amanda K; Strausbaugh, Linda D; Diaz, Patricia I

    2014-01-01

    The advent of next-generation sequencing has significantly facilitated characterization of the oral microbiome. Despite great efforts in streamlining the processes of sequencing and data curation, upstream steps required for amplicon library generation could still influence 16S rRNA gene-based microbial profiles. Among upstream processes, DNA extraction is a critical step that could represent a great source of bias. Accounting for bias introduced by extraction procedures is important when comparing studies that use different methods. Identifying the method that best portrays communities is also desirable. Accordingly, the aim of this study was to evaluate bias introduced by different DNA extraction procedures on oral microbiome profiles. Four DNA extraction methods were tested on mock communities consisting of seven representative oral bacteria. Additionally, supragingival plaque samples were collected from seven individuals and divided equally to test two commonly used DNA extraction procedures. Amplicon libraries of the 16S rRNA gene were generated and sequenced via 454-pyrosequencing. Evaluation of mock communities revealed that DNA yield and bacterial species representation varied with DNA extraction methods. Despite producing the lowest yield of DNA, a method that included bead beating was the only protocol capable of detecting all seven species in the mock community. Comparison of the performance of two commonly used methods (crude lysis and a chemical/enzymatic lysis+column-based DNA isolation) on plaque samples showed no effect of extraction protocols on taxa prevalence but global community structure and relative abundance of individual taxa were affected. At the phylum level, the latter method improved the recovery of Actinobacteria, Bacteroidetes, and Spirochaetes over crude lysis. DNA extraction distorts microbial profiles in simulated and clinical oral samples, reinforcing the importance of careful selection of a DNA extraction protocol to improve

  10. Obtaining representative community profiles of anaerobic digesters through optimisation of 16S rRNA amplicon sequencing protocols

    DEFF Research Database (Denmark)

    Kirkegaard, Rasmus Hansen; McIlroy, Simon Jon; Karst, Søren Michael

    A reliable and reproducible method for identification and quantification of the microorganisms involved in biogas production is important for the study and understanding of the microbial communities responsible for the function of anaerobic digester systems. DNA based identification using 16S r...... of the community composition . As such sample specific optimisation and standardisation of DNA extraction, as well PCR primer selection, are essential to minimising the potential for such biases. The aim of this study was to develop a protocol for optimized community profiling of anaerobic digesters. The Fast...

  11. Profiles of plasma parameters and density of negative hydrogen ions by laser detachment measurements in RF-driven ion sources; Profile der Plasmaparameter und Dichte negativer Wasserstoffionen mittels Laserdetachmentmessungen in HF-angeregten Ionenquellen

    Energy Technology Data Exchange (ETDEWEB)

    Christ-Koch, Sina

    2007-12-20

    This work shows the application of the Laserdetachment method for spatially resolved measurements of negative Hydrogen/Deuterium ion density. It was applied on a high power low pressure RF-driven ion source. The Laser detachment method is based on the measurement of electron currents on a positively biased Langmuir probe before and during/after a laser pulse. The density ratio of negative ions to electrons can be derived from the ratio of currents to the probe. The absolute density of negative ions can be obtained when the electron density is measured with the standard Langmuir probe setup. Measurements with the Langmuir probe additionally yield information about the floating and plasma potential, the electron temperature and the density of positive ions. The Laser detachment setup had to be adapted to the special conditions of the RF-driven source. In particular the existence of RF fields (1 MHz), high source potential (-20 kV), magnetic fields ({proportional_to} 7 mT) and caesium inside the source had to be considered. The density of negative ions could be identified in the range of n(H{sup -})=1.10{sup 17} 1/m{sup 3}, which is in the same order of magnitude as the electron density. Only the application of the Laser detachment method with the Langmuir probe measurements will yield spatially resolved plasma parameters and H- density profiles. The influence of diverse external parameters, such as pressure, RF-power, magnetic fields on the plasma parameters and their profiles were studied and explained. Hence, the measurements lead to a detailed understanding of the processes inside the source. (orig.)

  12. HPLC Evaluation of Phenolic Profile, Nutritive Content, and Antioxidant Capacity of Extracts Obtained from Punica granatum Fruit Peel

    Directory of Open Access Journals (Sweden)

    Sushil Kumar Middha

    2013-01-01

    Full Text Available This study revealed polyphenolic content, nutritive content, antioxidant activity, and phenolic profile of methanol and aqueous extracts of Punica granatum peel extract. For this, extracts were screened for possible antioxidant activities by free radical scavenging activity (DPPH, hydrogen peroxide scavenging activity and ferric-reducing antioxidant power (FRAP assays. The total phenolics and flavonoid recovered by methanolic (MPE and the water extract (AQPE were ranged from 185 ± 12.45 to 298.00 ± 24.86 mg GAE (gallic acid equivalents/gm and 23.05 ± 1.54 to 49.8 ± 2.14 quercetin (QE mg/g, respectively. The EC50 of herbal extracts ranged from 100 µg/ml (0.38 quercetin equivalents, for AQPE, 168 µg/ml (0.80 quercetin equivalents, for MPE. The phenolic profile in the methanolic extracts was investigated by chromatographic (HPLC method. About 5 different flavonoids, phenolic acids, and their derivatives including quercetin (1, rutin (2, gallic acid (3, ellagic acid (4, and punicalagin as a major ellagitannin (5 have been identified. Among both extracts, methanolic extract was the most effective. This report may be the first to show nutritive content and correlation analysis to suggest that phenols and flavonoids might contribute the high antioxidant activity of this fruit peel and establish it as a valuable natural antioxidant source applicable in the health food industry.

  13. Inherited susceptibility determines the distribution of dense low-density lipoprotein subfraction profiles in familial combined hyperlipidemia

    Energy Technology Data Exchange (ETDEWEB)

    Bredie, S.J.H.; Demacker, P.N.M.; Stalenhoef, A.F.H. [Univ. of Nijmegen (Netherlands)

    1996-04-01

    Familial combined hyperlipidemia (FCH) is a heritable lipid disorder, in which dense low-density lipoprotein (LDL) subfraction profiles due to a predominance of small dense LDL particles are frequently observed. These small dense LDL particles are associated with cardiovascular disease. Using segregation analysis, we investigated to what extent these LDL subfraction profiles are genetically determined; also, the mode of inheritance was studied. Individual LDL subfraction profiles were determined by density gradient ultracentrifugation in 623 individuals of 40 well-defined Dutch FCH families. The individual LDL subfraction profile was defined as a quantitative trait by the continuous variable K, a reliable estimate of the relative contribution of each LDL subfraction to the overall profile. Variation in parameter K due to age, sex, and hormonal status was taken into account by introducing liability classes. Segregation analysis was performed by fitting a series of class D regressive models were compared using log-likelihoot ratio tests. Our data show that 60% of the variability of parameter K could be explained by lipid and lipoprotein levels and that a major autosomal locus, recessively inherited, with a population frequency of .42 {+-} .07, and an additional polygenic component of .25 best explained the clustering of atherogenic dense LDL subfraction profiles in these FCH families. Therefore, dense LDL subfraction profiles, associated with elevated lipid levels, appear to have a genetic basis in FCH.

  14. [Attenuated Total Reflection Infrared Spectroscopy for Degradation Profile of High Density Polyethylene after Weathering Aging].

    Science.gov (United States)

    Guo, Jun-jun; Yan, Hua; Bao, He-bin; Wang, Xue-mei; Hu, Zhi-de; Yang, Jian-jian

    2015-06-01

    High density polyethylene (HDPE) was widely used as rotational packaging case in the material reserve field. The chemical changes of HDPE, exposed to particular climatic conditions of tropic marine atmosphere for one year-long in Wanning Hainan, were elucidated by the attenuated total reflection infrared spectroscopy (ATR-FTIR). The structural changes were studied qualitatively, mainly from the polymeric chain breaking, branching and oxidation to distinguish the degradation profile. The variations of crystallinity & carbonyl index were also studied quantitatively according to the characteristic peaks intensity & area ratio. Finally, the relationships between structural changes and mechanical properties were investigated. The results showed that the polymeric chain breaking & branching play a leading role before 3 months in the aging progress. Then oxidation phenomena gradually takes place during 3-6 months. The chain branching & oxidation were predominant factors after 6 months. Nine months later, the oxidation was saturated gradually. Furthermore, the aging process is positively correlated to the temperature and irradiation. After 12 months aging, the carbonyl index increased by 112 times and crystallinity was 10% higher than before. The tensile/bending modulus deceased faster than tensile/bending strength of HDPE. The linear degree of tensile modulus and carbonyl index was 0.97. The degree of linearity of tensile strength and crystallinity calculated by feature bands (720-730 cm(-1)) was 0.96. It showed that the mechanical properties of HDPE can be speculated from the structural changes by ATR-FTIR.

  15. Central depressions in the charge density profiles of the nuclei around $^{46}$Ar

    CERN Document Server

    Song, Jun Ling; Long, Wen Hui

    2015-01-01

    The occurrence of the proton bubble-like structure has been studied within the relativistic Hartree-Fock-Bogoliubov (RHFB) and relativistic Hartree-Bogoliubov (RHB) theories by exploring the bulk properties, the charge density profiles and single proton spectra of argon isotopes and $N = 28$ isotones. It is found that the RHFB calculations with PKA1 effective interaction, which can properly reproduce the charge radii of argon isotopes and the $Z=16$ proton shell nearby, do not support the occurrence of the proton bubble-like structure in argon isotopes due to the prediction of deeper bound proton orbit $\\pi2s_{1/2}$ than $\\pi1d_{3/2}$. For $N = 28$ isotones, $^{42}$Si and $^{40}$Mg are predicted by both RHFB and RHB models to have the proton bubble-like structure, owing to the large gap between the proton $\\pi2s_{1/2}$ and $\\pi1d_{5/2}$ orbits, namely the $Z=14$ proton shell. Therefore, $^{42}$Si is proposed as the potential candidate of proton bubble nucleus, which has longer life-time than $^{40}$Mg.

  16. A serum metabolomics-based profile in low bone mineral density postmenopausal women.

    Science.gov (United States)

    Miyamoto, Takeshi; Hirayama, Akiyoshi; Sato, Yuiko; Koboyashi, Tami; Katsuyama, Eri; Kanagawa, Hiroya; Miyamoto, Hiroya; Mori, Tomoaki; Yoshida, Shigeyuki; Fujie, Atsuhiro; Morita, Mayu; Watanabe, Ryuichi; Tando, Toshimi; Miyamoto, Kana; Tsuji, Takashi; Funayama, Atsushi; Nakamura, Masaya; Matsumoto, Morio; Soga, Tomoyoshi; Tomita, Masaru; Toyama, Yoshiaki

    2017-02-01

    Osteoporosis is characterized as a metabolic disorder of bone tissue, and various metabolic markers are now available to support its diagnosis and evaluate treatment effects. Substances produced as end products of metabolomic activities are the correlated factors to the biological or metabolic status, and thus, metabolites are considered highly sensitive markers of particular pathological states, including osteoporosis. Here we undertook comprehensive serum metabolomics analysis in postmenopausal women with or without low bone mineral density (low BMD vs controls) for the first time using capillary electrophoresis/mass spectrometry. Among the metabolites tested, 57 were detected in sera. Levels of hydroxyproline, Gly-Gly and cystine, differed significantly between groups, with Gly-Gly and cystine significantly lower in the low BMD group and hydroxyproline, a reported marker of osteoporosis, significantly higher. Levels of TRACP5b, a bone resorption marker, were significantly higher in the low BMD group, supporting the study's validity. Taken together, our findings represent novel metabolomic profiling in low BMD in postmenopausal women.

  17. RR Lyrae in XSTPS: The halo density profile in the North Galactic Cap

    CERN Document Server

    Faccioli, Lorenzo; Yuan, H -B; Zhang, H -H; Liu, X -W; Zhao, H -B; Yao, J -S

    2014-01-01

    We present a catalog of RR Lyrae stars (RRLs) observed by the Xuyi Schmidt Telescope Photometric Survey (XDSS). The area we consider is located in the North Galactic Cap, covering 376.75 sq deg at RA $\\approx$ 150 deg and Dec $\\approx$ 27 deg down to a magnitude limit of i $\\approx$ 19. Using the variability information afforded by the multi-epoch nature of our XDSS data, combined with colors from the Sloan Digital Sky Survey, we are able to identify candidate RRLs. We find 318 candidates, derive distances to them and estimate the detection efficiency. The majority of our candidates have more than 12 observations and for these we are able to calculate periods. These also allows us to estimate our contamination level, which we predict is between 30% to 40%. Finally we use the sample to probe the halo density profile in the 9-49 kpc range and find that it can be well fitted by a double power law. We find good agreement between this model and the models derived for the South Galactic Cap using the Watkins et al....

  18. Gravimetric and density profiling using the combination of surface acoustic waves and neutron reflectivity.

    Science.gov (United States)

    Toolan, Daniel T W; Barker, Robert; Gough, Tim; Topham, Paul D; Howse, Jonathan R; Glidle, Andrew

    2017-02-01

    A new approach is described herein, where neutron reflectivity measurements that probe changes in the density profile of thin films as they absorb material from the gas phase have been combined with a Love wave based gravimetric assay that measures the mass of absorbed material. This combination of techniques not only determines the spatial distribution of absorbed molecules, but also reveals the amount of void space within the thin film (a quantity that can be difficult to assess using neutron reflectivity measurements alone). The uptake of organic solvent vapours into spun cast films of polystyrene has been used as a model system with a view to this method having the potential for extension to the study of other systems. These could include, for example, humidity sensors, hydrogel swelling, biomolecule adsorption or transformations of electroactive and chemically reactive thin films. This is the first ever demonstration of combined neutron reflectivity and Love wave-based gravimetry and the experimental caveats, limitations and scope of the method are explored and discussed in detail.

  19. Modeling the convective stability of CO2 sequestration by a discontinuous and unstably stratified density profile

    Science.gov (United States)

    Wanstall, Taber; Hadji, Layachi

    2016-11-01

    The convective stability associated with carbon sequestration is modeled by adopting an unstably stratified basic profile having a step function density with top heavy carbon saturated layer overlying a lighter carbon free layer. The model takes into account the anisotropy in both permeability and carbon dioxide diffusion, and chemical reactions between the CO2 rich brine and host mineralogy. We carry out a linear stability analysis to derive the instability threshold parameters for a variety of CO2 boundary conditions. We solve for the minimum thickness of the carbon-rich layer at which convection sets in and quantify how its value is influenced by diffusion, anisotropy, permeability, reaction and type of boundary conditions. The discontinuity leads to convective concentration contours that have the shape of an asymmetric lens which we quantify by deriving and making use of the CO2 flux expressions at the interface. The linear problem is extended to the nonlinear regime, the analysis of which leads to the determination of a uniformly valid super critical steady solution.

  20. A comparative study on aromatic profiles of strawberry vinegars obtained using different conditions in the production process.

    Science.gov (United States)

    Ubeda, Cristina; Callejón, Raquel M; Troncoso, Ana M; Moreno-Rojas, Jose M; Peña, Francisco; Morales, M Lourdes

    2016-02-01

    Impact odorants in strawberry vinegars produced in different containers (glass, oak and cherry barrels) were determined by gas chromatography-olfactometry using modified frequency (MF) technique, and dynamic headspace gas chromatography-mass spectrometry. Aromatic profile of vinegar from strawberry cooked must was also studied. All strawberry vinegars retained certain impact odorants from strawberries: 3-nonen-2-one, (E,E)-2,4-decadienal, guaiacol, nerolidol, pantolactone+furaneol, eugenol, γ-dodecalactone and phenylacetic acid. Isovaleric acid, pantolactone+furaneol, p-vinylguaiacol, phenylacetic acid and vanillin were the most important aroma-active compounds in all vinegars. The strawberry cooked must vinegar accounted for the highest number of impact odorants. Wood barrels provided more aroma complexity than glass containers. Impact odorants with grassy characteristics were predominant in vinegar from glass containers, and those with sweet and fruity characteristics in vinegars from wood barrels. Principal component analysis indicated that the production process led to differences in the impact odorants.

  1. Genome-wide copy number profiling using high-density SNP array in chickens.

    Science.gov (United States)

    Yi, G; Qu, L; Chen, S; Xu, G; Yang, N

    2015-04-01

    Phenotypic diversity is a direct consequence resulting mainly from the impact of underlying genetic variation, and recent studies have shown that copy number variation (CNV) is emerging as an important contributor to both phenotypic variability and disease susceptibility. Herein, we performed a genome-wide CNV scan in 96 chickens from 12 diversified breeds, benefiting from the high-density Affymetrix 600 K SNP arrays. We identified a total of 231 autosomal CNV regions (CNVRs) encompassing 5.41 Mb of the chicken genome and corresponding to 0.59% of the autosomal sequence. The length of these CNVRs ranged from 2.6 to 586.2 kb with an average of 23.4 kb, including 130 gain, 93 loss and eight both gain and loss events. These CNVRs, especially deletions, had lower GC content and were located particularly in gene deserts. In particular, 102 CNVRs harbored 128 chicken genes, most of which were enriched in immune responses. We obtained 221 autosomal CNVRs after converting probe coordinates to Galgal3, and comparative analysis with previous studies illustrated that 153 of these CNVRs were regarded as novel events. Furthermore, qPCR assays were designed for 11 novel CNVRs, and eight (72.73%) were validated successfully. In this study, we demonstrated that the high-density 600 K SNP array can capture CNVs with higher efficiency and accuracy and highlighted the necessity of integrating multiple technologies and algorithms. Our findings provide a pioneering exploration of chicken CNVs based on a high-density SNP array, which contributes to a more comprehensive understanding of genetic variation in the chicken genome and is beneficial to unearthing potential CNVs underlying important traits of chickens. © 2015 Stichting International Foundation for Animal Genetics.

  2. Charge and current density profiles of a degenerate magnetized free-electron gas near a hard wall

    NARCIS (Netherlands)

    M.M. Kettenis; L.G. Suttorp

    1998-01-01

    The charge and current densities of a completely degenerate free-electron gas in a uniform magnetic field are found to have a damped oscillatory spatial dependence near a wall that is parallel to the magnetic field. For large distances from the wall the behaviour of the associated profile functions

  3. Stereolithography based method of creating custom gas density profile targets for high intensity laser-plasma experiments.

    Science.gov (United States)

    Jolly, S W; He, Z; McGuffey, C; Schumaker, W; Krushelnick, K; Thomas, A G R

    2012-07-01

    Laser based stereolithography methods are shown to be useful for production of gas targets for high intensity laser-plasma interaction experiments. A cylindrically symmetric nozzle with an opening of approximately 100 μm and a periodic attachment of variable periodicity are outlined in detail with associated density profile characterization. Both components are durable within the limits of relevant experiments.

  4. COMPARISON OF FATTY ACID PROFILES OF MALE AND FEMALE GIANT RED SHRIMPS (Aristaeomorpha foliacea RISSO, 1827) OBTAINED FROM MEDITERRANEAN SEA

    OpenAIRE

    İ.A. Olgunoglu; E. Artar; M. Gocer

    2015-01-01

    This study was carried out to detect the concentration of fatty acid in female and male specimens of commercially important giant red shrimp (Aristaeomorpha foliacea) obtained from (including 20 male shrimps and also 20 female shrimp) Mediterranean Sea. In fatty acid composition, the saturated fatty acid fraction was dominant, followed by polyunsaturated fatty acid and monounsaturated fatty acid for both sexes. The analyses indicated that PUFAs, and the MUFAs content were higher in female shr...

  5. Chemical profile and antimicrobial activity of Boldo (Peumus boldus Molina) extracts obtained by compressed carbon dioxide extraction

    OpenAIRE

    Mazutti,M.; Mossi,A. J.; CANSIAN,R.L.; Corazza,M. L.; Dariva,C.; Vladimir Oliveira,J.

    2008-01-01

    This work reports the effects of temperature (20 to 50ºC) and pressure (100 to 250 bar) on the extraction yield, chemical characteristics and antimicrobial activity of extracts of Peumus boldus Molina obtained by compressed carbon dioxide extraction. Results showed that the extraction variables affect the extraction yield and the chemical distribution of the major compounds present in the extracts. The extracts were chemically analyzed with regard to 1,8-cineole, trans-sabinene, pinocarveol, ...

  6. Chemical profile and antimicrobial activity of Boldo (Peumus boldus Molina) extracts obtained by compressed carbon dioxide extraction

    OpenAIRE

    Mazutti,M.; A J Mossi; CANSIAN,R.L.; M. L. Corazza; Dariva,C.; J. Vladimir Oliveira

    2008-01-01

    This work reports the effects of temperature (20 to 50ºC) and pressure (100 to 250 bar) on the extraction yield, chemical characteristics and antimicrobial activity of extracts of Peumus boldus Molina obtained by compressed carbon dioxide extraction. Results showed that the extraction variables affect the extraction yield and the chemical distribution of the major compounds present in the extracts. The extracts were chemically analyzed with regard to 1,8-cineole, trans-sabinene, pinocarveol, ...

  7. CLASH-VLT: The stellar mass function and stellar mass density profile of the z=0.44 cluster of galaxies MACS J1206.2-0847

    CERN Document Server

    Annunziatella, M; Mercurio, A.; Nonino, M.; Rosati, P.; Balestra, I.; Presotto, V.; Girardi, M.; Gobat, R.; Grillo, C.; Medezinski, E.; Kelson, D.; Postman, M.; Scodeggio, M.; Brescia, M.; Sartoris, B.; Demarco, R.; Fritz, A.; Koekemoer, A.; Lemze, D.; Lombardi, M.; Bradley, L.; Coe, D.; Donahue, M.; Regös, E.; Umetsu, K.; Vanzella, E.; Infante, L.; Kuchner, U.; Maier, C.; Verdugo, M.; Ziegler, B.

    2014-01-01

    Context. The study of the galaxy stellar mass function (SMF) in relation to the galaxy environment and the stellar mass density profile, rho(r), is a powerful tool to constrain models of galaxy evolution. Aims. We determine the SMF of the z=0.44 cluster of galaxies MACS J1206.2-0847 separately for passive and star-forming (SF) galaxies, in different regions of the cluster, from the center out to approximately 2 virial radii. We also determine rho(r) to compare it to the number density and total mass density profiles. Methods. We use the dataset from the CLASH-VLT survey. Stellar masses are obtained by SED fitting on 5-band photometric data obtained at the Subaru telescope. We identify 1363 cluster members down to a stellar mass of 10^9.5 Msolar. Results. The whole cluster SMF is well fitted by a double Schechter function. The SMFs of cluster SF and passive galaxies are statistically different. The SMF of the SF cluster galaxies does not depend on the environment. The SMF of the passive population has a signif...

  8. Profiling of Ionospheric Electron Density Based on FormoSat-3/COSMIC Data: Results from the Intense Observation Period Experiment

    Directory of Open Access Journals (Sweden)

    Lung-Chih Tsai

    2009-01-01

    Full Text Available Multi-channel Global Position System (GPS carrier phase signals received by the FormoSat-3 (FS3/COSMIC program's six low Earth orbiting (LEO satellites were used to undertake active limb sounding of the Earth¡¦s atmosphere and ionosphere via radio occultation (RO. In this study, the effects of large-scale horizontal gradients and/or inhomogeneous ionospheric electron densities (ne were considered by developing an iterative scheme to determine "compensated" total electron content (TEC values through nearby occultation observations. Using an iterative Abel inversion through "compensated" TEC values, more than one-hundred and eighty thousand vertical ionospheric ne profiles were collected during the intense observation period (IOP of 20 June - 27 September (day number 171 to 270 2006. Coincidences of GPS RO observations to ionospheric ne ionosonde data from forty-nine worldwide stations have been examined. It is found that the iterative scheme gives improved retrievals over the standard Abel inversion. From several thousand matches within the IOP experiment, the root mean square (rms foF2 differences between the ionosonde measurements and the FS3/COSMIC retrievals are improved from 1.67 to 1.07 MHz. The results also show improvement in the overestimates (underestimates on low (high retrieved foF2s, while the obtained hmF2s give better agreement with ionosonde observations.

  9. Comparison of P- and S-wave velocity profiles obtained from surface seismic refraction/reflection and downhole data

    Science.gov (United States)

    Williams, R.A.; Stephenson, W.J.; Odum, J.K.

    2003-01-01

    High-resolution seismic-reflection/refraction data were acquired on the ground surface at six locations to compare with near-surface seismic-velocity downhole measurements. Measurement sites were in Seattle, WA, the San Francisco Bay Area, CA, and the San Fernando Valley, CA. We quantitatively compared the data in terms of the average shear-wave velocity to 30-m depth (Vs30), and by the ratio of the relative site amplification produced by the velocity profiles of each data type over a specified set of quarter-wavelength frequencies. In terms of Vs30, similar values were determined from the two methods. There is reflections and first-arrival phase delays are essential for identifying velocity inversions. The results suggest that seismic reflection/refraction data are a fast, non-invasive, and less expensive alternative to downhole data for determining Vs30. In addition, we emphasize that some P- and S-wave reflection travel times can directly indicate the frequencies of potentially damaging earthquake site resonances. A strong correlation between the simple S-wave first-arrival travel time/apparent velocity on the ground surface at 100 m offset from the seismic source and the Vs30 value for that site is an additional unique feature of the reflection/refraction data that could greatly simplify Vs30 determinations. ?? 2003 Elsevier Science B.V. All rights reserved.

  10. Vertical microphysical profiles of convective clouds as a tool for obtaining aerosol cloud-mediated climate forcings

    Energy Technology Data Exchange (ETDEWEB)

    Rosenfeld, Daniel [Hebrew Univ. of Jerusalem (Israel)

    2015-12-23

    Quantifying the aerosol/cloud-mediated radiative effect at a global scale requires simultaneous satellite retrievals of cloud condensation nuclei (CCN) concentrations and cloud base updraft velocities (Wb). Hitherto, the inability to do so has been a major cause of high uncertainty regarding anthropogenic aerosol/cloud-mediated radiative forcing. This can be addressed by the emerging capability of estimating CCN and Wb of boundary layer convective clouds from an operational polar orbiting weather satellite. Our methodology uses such clouds as an effective analog for CCN chambers. The cloud base supersaturation (S) is determined by Wb and the satellite-retrieved cloud base drop concentrations (Ndb), which is the same as CCN(S). Developing and validating this methodology was possible thanks to the ASR/ARM measurements of CCN and vertical updraft profiles. Validation against ground-based CCN instruments at the ARM sites in Oklahoma, Manaus, and onboard a ship in the northeast Pacific showed a retrieval accuracy of ±25% to ±30% for individual satellite overpasses. The methodology is presently limited to boundary layer not raining convective clouds of at least 1 km depth that are not obscured by upper layer clouds, including semitransparent cirrus. The limitation for small solar backscattering angles of <25º restricts the satellite coverage to ~25% of the world area in a single day. This methodology will likely allow overcoming the challenge of quantifying the aerosol indirect effect and facilitate a substantial reduction of the uncertainty in anthropogenic climate forcing.

  11. The effects of ellipticity and substructure on estimates of cluster density profiles based on lensing and kinematics

    Science.gov (United States)

    Meneghetti, Massimo; Bartelmann, Matthias; Jenkins, Adrian; Frenk, Carlos

    2007-10-01

    We address the question of how well the density profile of galaxy clusters can be determined by combining strong lensing and velocity dispersion data. We use cosmological dark matter simulations of clusters to test the reliability of the method, producing mock catalogues of tangential and radial gravitational arcs and simulating the radial velocity dispersion profile of the cluster brightest central galaxy. The density profiles of the simulated clusters closely follow the Navarro, Frenk & White (NFW) form, but we find that the recovered values of the inner slope are systematically underestimated, by about 0.4 in the mean, if the lens is assumed to be axially symmetric. However, if the ellipticity and orientation of the isocontours of the cluster lensing potential are taken into account, then the inner slopes can be recovered quite accurately for a significant subset of the clusters whose central surface density profiles appear the most regular. These have lensing potentials with ellipticities in the range 0.15-0.4. Further simulations projecting one cluster along many random lines of sight show that, even for lower ellipticities, the central slopes are underestimated by ~10-35per cent. These simulations closely mimic past observations, suggesting that existing estimates of the central slopes may be biased towards low values. For the remaining clusters, where the lensing potential is strongly perturbed by active merging or by substructure, the correct determination of the inner slope requires a more accurate model for the lens. When the halo profile is modelled by a generalized NFW profile, we find that the inferred scale radius and characteristic density, unlike the inner slope, are generally poorly constrained, since there is a strong degeneracy between these two parameters.

  12. Improved density profile measurements in the C-2U advanced beam-driven Field-Reversed Configuration (FRC) plasmas

    Science.gov (United States)

    Beall, M.; Deng, B. H.; Gota, H.

    2016-11-01

    In the prior C-2 experiment, electron density was measured using a two-color 6-chord CO2/HeNe interferometer. Analysis shows that high-frequency common mode phase noise can be reduced by a factor of 3 by constructing a reference chord. In the system upgrade from C-2 to C-2U a 4-chord far-infrared laser interferometer was developed, which demonstrated superior sensitivity (1 × 1016 m-2 at >1 MHz bandwidth) and solved the under spatial sampling issue of the C-2 interferometer system. Improved density-profile measurement results are presented in this paper, including evidence of fast-ion modified density profile and stabilization of the n = 1 plasma wobble mode.

  13. Gene expression profiles of Beta-cell enriched tissue obtained by laser capture microdissection from subjects with type 2 diabetes.

    Directory of Open Access Journals (Sweden)

    Lorella Marselli

    Full Text Available BACKGROUND: Changes in gene expression in pancreatic beta-cells from type 2 diabetes (T2D should provide insights into their abnormal insulin secretion and turnover. METHODOLOGY/PRINCIPAL FINDINGS: Frozen sections were obtained from cadaver pancreases of 10 control and 10 T2D human subjects. Beta-cell enriched samples were obtained by laser capture microdissection (LCM. RNA was extracted, amplified and subjected to microarray analysis. Further analysis was performed with DNA-Chip Analyzer (dChip and Gene Set Enrichment Analysis (GSEA software. There were changes in expression of genes linked to glucotoxicity. Evidence of oxidative stress was provided by upregulation of several metallothionein genes. There were few changes in the major genes associated with cell cycle, apoptosis or endoplasmic reticulum stress. There was differential expression of genes associated with pancreatic regeneration, most notably upregulation of members of the regenerating islet gene (REG family and metalloproteinase 7 (MMP7. Some of the genes found in GWAS studies to be related to T2D were also found to be differentially expressed. IGF2BP2, TSPAN8, and HNF1B (TCF2 were upregulated while JAZF1 and SLC30A8 were downregulated. CONCLUSIONS/SIGNIFICANCE: This study made possible by LCM has identified many novel changes in gene expression that enhance understanding of the pathogenesis of T2D.

  14. The surface density profile of NGC 6388 : a good candidate for harboring an intermediate-mass black hole

    CERN Document Server

    Lanzoni, B; Ferraro, F R; Miocchi, P; Valenti, E; Rood, R T

    2007-01-01

    We have used a combination of high resolution (HST ACS-HRC, ACS-WFC, and WFPC2) and wide-field (ESO-WFI) observations of the galactic globular cluster NGC 6388 to derive its center of gravity, projected density profile, and central surface brightness profile. While the overall projected profiles are well fit by a King model with intermediate concentration (c=1.8) and sizable core radius (rc=7"), a significant power law (with slope \\alpha=-0.2) deviation from a flat core behavior has been detected within the inner 1 arcsecond. These properties suggest the presence of a central intermediate mass black hole. The observed profiles are well reproduced by a multi-mass isotropic, spherical model including a black hole with a mass of ~5.7x10^3 Msol.

  15. Metabolite profiling of Clinacanthus nutans leaves extracts obtained from different drying methods by 1H NMR-based metabolomics

    Science.gov (United States)

    Hashim, Noor Haslinda Noor; Latip, Jalifah; Khatib, Alfi

    2016-11-01

    The metabolites of Clinacanthus nutans leaves extracts and their dependence on drying process were systematically characterized using 1H nuclear magnetic resonance spectroscopy (NMR) multivariate data analysis. Principal component analysis (PCA) and partial least square-discriminant analysis (PLS-DA) were able to distinguish the leaves extracts obtained from different drying methods. The identified metabolites were carbohydrates, amino acid, flavonoids and sulfur glucoside compounds. The major metabolites responsible for the separation in PLS-DA loading plots were lupeol, cycloclinacosides, betulin, cerebrosides and choline. The results showed that the combination of 1H NMR spectroscopy and multivariate data analyses could act as an efficient technique to understand the C. nutans composition and its variation.

  16. Compact and high-particle-flux thermal-lithium-beam probe system for measurement of two-dimensional electron density profile.

    Science.gov (United States)

    Shibata, Y; Manabe, T; Kajita, S; Ohno, N; Takagi, M; Tsuchiya, H; Morisaki, T

    2014-09-01

    A compact and high-particle-flux thermal-lithium-beam source for two-dimensional measurement of electron density profiles has been developed. The thermal-lithium-beam oven is heated by a carbon heater. In this system, the maximum particle flux of the thermal lithium beam was ~4 × 10(19) m(-2) s(-1) when the temperature of the thermal-lithium-beam oven was 900 K. The electron density profile was evaluated in the small tokamak device HYBTOK-II. The electron density profile was reconstructed using the thermal-lithium-beam probe data and this profile was consistent with the electron density profile measured with a Langmuir electrostatic probe. We confirm that the developed thermal-lithium-beam probe can be used to measure the two-dimensional electron density profile with high time and spatial resolutions.

  17. Effect of Selenium-Enriched Agaricus bisporus (Higher Basidiomycetes) Extracts, Obtained by Pressurized Water Extraction, on the Expression of Cholesterol Homeostasis Related Genes by Low-Density Array.

    Science.gov (United States)

    Gil-Ramírez, Alicia; Soler-Rivas, Cristina; Rodriguez-Casado, Arantxa; Ruiz-Rodríguez, Alejandro; Reglero, Guillermo; Marín, Francisco Ramón

    2015-01-01

    Culinary-medicinal mushrooms are able to lower blood cholesterol levels in animal models by different mechanisms. They might impair the endogenous cholesterol synthesis and exogenous cholesterol absorption during digestion. Mushroom extracts, obtained using pressurized water extractions (PWE) from Agaricus bisporus basidiomes, supplemented or not supplemented with selenium, were applied to HepG2 cell cultures to study the expression of 19 genes related to cholesterol homeostasis by low-density arrays (LDA). Only the PWE fractions obtained at 25°C showed 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) inhibitory activity. Besides the enzymatic inhibition, PWE extracts may downregulate some of the key genes involved in the cholesterol homeostasis, such as the squalene synthase gene (FDFT1), since its mRNA expression falls by one third of its initial value. In summary, A. bisporus extracts may also modulate biological cholesterol levels by molecular mechanisms further than the enzymatic way previously reported.

  18. Density profile of dark matter haloes and galaxies in the Horizon-AGN simulation: the impact of AGN feedback

    CERN Document Server

    Peirani, S; Volonteri, M; Devriendt, J; Bundy, K; Silk, J; Pichon, C; Kaviraj, S; Gavazzi, R; Habouzit, M

    2016-01-01

    Using a suite of three large cosmological hydrodynamical simulations, Horizon-AGN, Horizon-noAGN (no AGN feedback) and Horizon-DM (no baryons), we investigate how a typical sub-grid model for AGN feedback affects the evolution of the inner density profiles of massive dark matter haloes and galaxies. Based on direct object-to-object comparisons, we find that the integrated inner mass and density slope differences between objects formed in these three simulations (hereafter, H_AGN, H_noAGN and H_DM) significantly evolve with time. More specifically, at high redshift (z~5), the mean central density profiles of H_AGN and H_noAGN dark matter haloes tend to be much steeper than their H_DM counterparts owing to the rapidly growing baryonic component and ensuing adiabatic contraction. By z~1.5, these mean halo density profiles in H_AGN have flattened, pummelled by powerful AGN activity ("quasar mode"): the integrated inner mass difference gaps with H_noAGN haloes have widened, and those with H_DM haloes have narrowed...

  19. Size and CT density of iodine-containing ethosomal vesicles obtained by membrane extrusion: potential for use as CT contrast agents.

    Science.gov (United States)

    Na, Bomin; Choi, Byoung Wook; Kim, Bumsang

    2013-11-01

    Computed tomography (CT) is the primary non-invasive imaging technique used for most patients with suspected liver disease. In order to improve liver-specific imaging properties and prevent toxic effects in patients with compromised renal function, we investigated the encapsulation of iodine within ethosomal vesicles. As a first step in the development of novel contrast agents using ethosomes for CT imaging applications, iodine was entrapped within ethosomes and iodine-containing ethosomes of the desired size were obtained by extrusion using a polycarbonate membrane with a defined pore size. Ethosomes containing iodine showed a relatively high CT density, which decreased when they were extruded, due to the rupture and re-formation of the lipid bilayer of the ethosome. However, when a solution with a high iodine concentration was used as a dispersion media during the extrusion process, the decrease in CT density could be prevented. In addition, ethosomes containing iodine were taken up efficiently by macrophages, which are abundant in the liver, and these ethosomes exhibited no cellular toxicity. These results demonstrate that iodine could be entrapped within ethosomal vesicles, giving the ethosomes a relatively high CT density, and that the extrusion technique used in this study could conveniently and reproducibly produce ethosomal vesicles with a desired size. Therefore, ethosomes containing iodine, as prepared in this study, have potential as contrast agents with applications in CT imaging.

  20. Usability of optical spectrum analyzer in measuring atmospheric CO2 and CH4 column densities: inspection with FTS and aircraft profiles in situ

    Directory of Open Access Journals (Sweden)

    I. Morino

    2012-11-01

    Full Text Available The practical usefulness of a desktop optical spectrum analyzer (OSA for measuring atmospheric CO2 and CH4 column densities at surface sites was examined in two separate measurement campaigns. The first comparison involved operating the OSA in parallel with a high resolution Fourier transform spectroscopy (FTS situated at the University of Wollongong in Australia. Scale factors for the OSA were assigned for the column average volume mixing ratios of xCO2 and xCH4 by comparing with the well-studied FTS. The second method is a calibration against aircraft CO2 profiles in situ over Tsukuba in Japan obtained during a GOSAT validation campaign carried out from 28 January to 7 February 2011. The xCO2 values in the campaign, deduced by use of a derived OSA scale factor, were in excellent agreement with the integrated aircraft profiles.

  1. Usability of optical spectrum analyzer in measuring atmospheric CO2 and CH4 column densities: substantiation with FTS and aircraft profiles in situ

    Directory of Open Access Journals (Sweden)

    I. Morino

    2012-06-01

    Full Text Available The practical usefulness of a desktop optical spectrum analyzer (OSA for measuring atmospheric CO2 and CH4 column densities at surface sites was examined in two separate measurement campaigns. The first involved a long term measurement in parallel with a high resolution Fourier transform spectroscopy (FTS studies at the University of Wollongong in Australia. Scale factors of the OSA were assigned for the column average volume mixing ratios of xCO2 and xCH4 by comparing with the well-studied FTS. The second method is a calibration against aircraft CO2 profiles in situ over Tsukuba in Japan obtained during a GOSAT validation campaign carried out from 28 January to 7 February 2011. The xCO2 values in the campaign, deduced by use of a derived OSA scale factor, were in excellent agreement with the integrated aircraft profiles.

  2. Molecular Typing and Virulence Gene Profiles of Enterotoxin Gene Cluster (egc)-Positive Staphylococcus aureus Isolates Obtained from Various Food and Clinical Specimens.

    Science.gov (United States)

    Song, Minghui; Shi, Chunlei; Xu, Xuebing; Shi, Xianming

    2016-11-01

    The enterotoxin gene cluster (egc) has been proposed to contribute to the Staphylococcus aureus colonization, which highlights the need to evaluate genetic diversity and virulence gene profiles of the egc-positive population. Here, a total of 43 egc-positive isolates (16.2%) were identified from 266 S. aureus isolates that were obtained from various food and clinical specimens in Shanghai. Seven different egc profiles were found based on the polymerase chain reaction (PCR) result for egc genes. Then, these 43 egc-positive isolates were further typed by multilocus sequence typing, pulsed-field gel electrophoresis (PFGE), multiple-locus variable-number tandem-repeat analysis (MLVA), and accessory gene regulatory (agr) typing. It showed that the 43 egc-positive isolates displayed 17 sequence types, 28 PFGE patterns, 29 MLVA types, and 4 agr types, respectively. Among them, the dominant clonal lineage was CC5-agr II (48.84%). Thirty toxin and 20 adhesion-associated genes were detected by PCR in egc-positive isolates. Notably, invasive toxin genes showed a high prevalence, such as 76.7% for Panton-Valentine leukocidin encoding genes, 27.9% for sec, and 23.3% for tsst-1. Most of the examined adhesion-associated genes were found to be conserved (76.7-100%), whereas the fnbB gene was only found in 8 (18.6%) isolates. In addition, 33 toxin gene profiles and 13 adhesion gene profiles were identified, respectively. Our results imply that isolates belonging to the same clonal lineage harbored similar adhesion gene profiles but diverse toxin gene profiles. Overall, the high prevalence of invasive virulence genes increases the potential risk of egc-positive isolates in S. aureus infection.

  3. Evaluation of volatile profiles obtained for minimally-processed pineapple fruit samples during storage by headspace-solid phase microextraction gas chromatography-mass spectrometry

    Directory of Open Access Journals (Sweden)

    Francielle Crocetta TURAZZI

    Full Text Available Abstract This paper describes the application of the solid-phase microextraction (SPME technique for the determination and monitoring of the volatile profile of minimally-processed pineapple fruit stored at various temperatures (-12 °C, 4 °C and 25 °C for different periods (1, 4 and 10 days. The SPME fiber coating composed of Car/PDMS presented the best performance. The optimal extraction conditions obtained through a Doehlert design were 60 min at 35 °C. The profiles for the volatile compounds content of the fruit at each stage of storage were determined by gas chromatography-mass spectrometry (GC-MS. The variation in the volatile profile over time was greater when the fruit samples were stored at 25 °C and at -12 °C compared to 4 °C. Thus, according to the volatile profiles associated with the storage conditions evaluated in this study, packaged pineapple retains best its fresh fruit aroma when stored at 4 °C.

  4. Characterizing intra-annual density fluctuations using fine-spatial resolution blue intensity profiles

    Science.gov (United States)

    Babst, Flurin; Wright, William; Szejner, Paul; Wells, Leon; Belmecheri, Soumaya; Monson, Russell

    2016-04-01

    Rapidly rising evaporative demand threatens forests in semi-arid areas around the world, but the timing of stem growth response to drought is often coarsely known. This is partly due to a shortage of sub-annual growth records, particularly outside the Mediterranean region where most intra-annual density fluctuation (IADF) chronologies are based. We anticipate that an automated, cost-effective, and easily implementable method to characterize IADFs could foster more widespread development of sub-annual chronologies. Here, we applied a peak detection algorithm to fine-spatial resolution blue intensity (BI) profiles of Ponderosa pine tree rings from two sites located in neighboring mountain ranges in southern Arizona (~300 m elevation difference). This automated procedure proved reliable to isolate and characterize IADFs, thus offering an efficient and objective alternative to visual identification. Out of seven investigated BI parameters, peak height, width, and area showed satisfactory chronology statistics. We assessed the response of these BI and radial growth parameters to six monthly-resolved climate variables and to the onset date of the North American summer monsoon (NAM). The NAM is an atmospheric mode that provides a clear time marker for the termination of a pre-summer drought period (May-June) causing regular IADFs in trees growing near the dry margin of their distribution range. We observed divergent water limitation at the two sites, despite comparable site characteristics. Radial growth at the lower-elevation site depended mainly on winter precipitation, whereas the higher site relied on spring and monsoon precipitation. The pre-summer drought period indeed promoted IADFs in early ring portions at both sites. Yet, IADFs at the higher site were only formed, if spring was sufficiently humid to assume enough radial growth. Late-position IADFs were caused by a weak monsoon and additionally promoted by favorable conditions towards the end of the growing

  5. Long Term Three-dimensional Model Parameterization and Evaluation By The Use of Combined Continuous Ozone Lidar Profiles, Vertical Wind Profiles and Ground Based Monitors Obtained During The Escompte Campaign

    Science.gov (United States)

    Frejafon, E.; Robin, D.; Kalthoff, N.; Pesch, M.

    ESCOMPTE 2001 is a field experiment that took place in the southeast of France, in order to understand chemical transformation and transport and then to improve numer- ical models devoted to pollution study and forecasting. To achieve this goal, a stand alone ozone LIDAR was installed from June 11th to July 13th in Cadarache, 30 km northeast of the cities of Marseilles and Aix-en-Provence, downwind from the ozone precursors emissions zones in case of sea-breeze development conditions. This full automatic LIDAR provided vertical profiles of ozone concentration and also the mix- ing height dynamics, between 100 m and 2 500 m, with a spatial resolution of less than 100 m and a temporal resolution of 3 minutes. Data obtained with the LIDAR were connected to ground based ozone monitor installed on the same location by the air quality network, in order to evaluate the data quality and to obtain ozone verti- cal profiles from the ground level up to the free troposphere, which is an optimized support for tree-dimensional photochemical models parameterization and evaluation. The ozone diurnal cycles and the daily atmospheric stratification recorded during this month show the fast dynamics during pollution episodes, resulting from combined photochemical and transport effects in case of sea-breeze. They also specify the re- maining ozone vertical structure during non polluted episodes. Such long-term infor- mation is then a consistent support for model parameterization and evaluation, as it can specify the ozone concentration and the PBL dynamics from the beginning to the last end of a pollution episode. This one month vertical ozone profiles, which were compiled in a movie, will be presented and discussed more precisely. The obtained results, combined with continuous vertical wind profiles obtained with a SODAR and a ground based meteorological station installed on the same location, give access to the continuous ozone flux vertical profiles and the PBL dynamics.

  6. Genetic Polymorphisms and Phenotypic Profiles of Sulfadiazine-Resistant and Sensitive Toxoplasma gondii Isolates Obtained from Newborns with Congenital Toxoplasmosis in Minas Gerais, Brazil

    Science.gov (United States)

    Silva, Letícia Azevedo; Reis-Cunha, João Luís; Bartholomeu, Daniella Castanheira; Vítor, Ricardo Wagner Almeida

    2017-01-01

    Background Previous Toxoplasma gondii studies revealed that mutations in the dhps (dihydropteroate synthase) gene are associated with resistance to sulfonamides. Although Brazilian strains are genotypically different, very limited data are available regarding the susceptibility of strains obtained from human to sulfonamides. The aim of this study was to evaluate the efficacy of sulfadiazine (SDZ) against Brazilian isolates of T. gondii and verify whether isolates present polymorphisms in the dhps gene. We also investigated whether the virulence-phenotype and/or genotype were associated with the profile of susceptibility to SDZ. Methods Five T. gondii isolates obtained from newborns with congenital toxoplasmosis were used to verify susceptibility. Mice were infected with 104 tachyzoites and orally treated with different doses of SDZ. The mortality curve was evaluated by the Log-rank test. The presence of polymorphisms in the dhps gene was verified using sequencing. A descriptive analysis for 11 Brazilian isolates was used to assess the association between susceptibility, genotype, and virulence-phenotype. Results Statistical analysis showed that TgCTBr03, 07, 08, and 16 isolates were susceptible to SDZ, whereas TgCTBr11 isolate presented a profile of resistance to SDZ. Nineteen polymorphisms were identified in dhps exons. Seven polymorphisms corresponded to non-synonymous mutations, with four being new mutations, described for the first time in this study. No association was found between the profile of susceptibility and the virulence-phenotype or genotype of the parasite. Conclusions There is a high variability in the susceptibilities of Brazilian T. gondii strains to SDZ, with evidence of drug resistance. Despite the large number of polymorphisms identified, the profile of susceptibility to SDZ was not associated with any of the dhps variants identified in this study. Other genetic factors, not yet determined, may be associated with the resistance to SDZ; thus

  7. Validation of improved Multi-Mode model for density, temperature and toroidal rotation profiles using PTRANSP simulations

    Science.gov (United States)

    Luo, L.; Bateman, G.; Kritz, A. H.; Pankin, A. Y.; Rafiq, T.; McCune, D. C.; Budny, R. V.

    2010-11-01

    Advances in the Multi-Mode model include an improved Weiland model for the ITG and TEM modes [1] and a new model for the drift resistive inertial ballooning modes (DRIBM) [2]. Advances in the PTRANSP code include an improved algorithm for the particle density evolution. Validation studies are carried out for the improved Multi-Mode model using PTRANSP simulations. In order to allow tight coupling with stiff transport models, all of the transport equations for main ion and impurity density profiles as well as electron temperature, ion temperature and toroidal angular rotation profiles are advanced simultaneously by the PTRANSP solver. The Plasma State connects the new solver to the rest of PTRANSP. The solver uses several techniques to control numerical stability. Simulation results for density, temperature and rotation frequency profiles are compared with experimental data for L-mode and H-mode discharges. [4pt] [1] J.Weiland et al., Nucl. Fusion 49 (2009) 965933; F.D. Halpern et al., Phys. Plasmas 15 (2008) 065033 [2] T. Rafiq et al., to appear in Phys. Plasmas (2010)

  8. Numerical Simulation of Hot Accretion Flows (I): A Large Radial Dynamical Range and the Density Profile of Accretion Flow

    CERN Document Server

    Yuan, Feng; Bu, Defu

    2012-01-01

    Numerical simulations of hot accretion flow have shown that the mass accretion rate decreases with decreasing radius; consequently the density profile of accretion flow becomes flatter compared to the case of a constant accretion rate. This result has important theoretical and observational implications. However, because of technical difficulties, the radial dynamic range in almost all previous simulations usually spans at most two orders of magnitude. This small dynamical range, combined with the effects of boundary conditions, makes the simulation results suspectable. Especially, the radial profiles of density and accretion rate may not be precise enough to be used to compare with observations. In this paper we present a "two-zone" approach to expand the radial dynamical range from two to four orders of magnitude. We confirm previous results and find that from $r_s$ to $ 10^4r_s$ the radial profiles of accretion rate and density can be well described by $\\dot{M}(r)\\propto r^s$ and $\\rho\\propto r^{-p}$. The ...

  9. A long-term study on the deletion criterion of questionable electron density profiles caused by ionospheric irregularities - COSMIC radio occultation technique

    Science.gov (United States)

    Uma, G.; Brahmanandam, P. S.; Chu, Y. H.

    2016-06-01

    The crucial assumption made in the retrieval of radio-occultated atmospheric parameters is the spherical symmetry of the atmospheric refractive index, which implies that no horizontal gradient of the refractive index exists along the spherical shell. Nevertheless, the presence of density irregularities will lead to scintillation and multipath effects that often create highly fluctuating and random electron density profiles. In this study, it is proposed a reliable data quality control (QC) approach to remove questionable electron density profiles (due to the presence of ionospheric irregularities) retrieved using the COSMIC radio occultation (RO) technique based on two parameters, namely, the gradient and fluctuation of the topside density profile. Statistics of seven years density profiles (July 2006-May 2013) are presented by determining the aforementioned parameters for every density profile. The main advantage of this data QC is that it uses COSMIC RO electron density profiles retrieved from the slant total electron content (TEC) that is estimated from the excess phases of the GPS L1 and L2 frequencies only to delete the questionable profiles, instead of relying on any model and other observations. A systematic criterion has been developed based on the statistics to relinquish the so-called questionable density profiles. The computed gradients and fluctuations of the topside ionosphere electron density profiles have shown a few important features including, solar activity dependency and pronounced variations in between around +40° and -40° latitudes. After the removal of questionable profiles, both peak densities and heights of the ionosphere F layer are presented globally in different seasons of years during 2007 and 2012 that revealed several important features.

  10. Cross-correlation Weak Lensing of SDSS galaxy Clusters II: Cluster Density Profiles and the Mass--Richness Relation

    Energy Technology Data Exchange (ETDEWEB)

    Johnston, David E.; Sheldon, Erin S.; Wechsler, Risa H.; Rozo, Eduardo; Koester, Benjamin P.; Frieman, Joshua A.; McKay, Timothy A.; Evrard, August E.; Becker, Matthew; Annis, James

    2007-09-28

    We interpret and model the statistical weak lensing measurements around 130,000 groups and clusters of galaxies in the Sloan Digital Sky Survey presented by Sheldon et al. (2007). We present non-parametric inversions of the 2D shear profiles to the mean 3D cluster density and mass profiles in bins of both optical richness and cluster i-band luminosity. Since the mean cluster density profile is proportional to the cluster-mass correlation function, the mean profile is spherically symmetric by the assumptions of large-scale homogeneity and isotropy. We correct the inferred 3D profiles for systematic effects, including non-linear shear and the fact that cluster halos are not all precisely centered on their brightest galaxies. We also model the measured cluster shear profile as a sum of contributions from the brightest central galaxy, the cluster dark matter halo, and neighboring halos. We infer the relations between mean cluster virial mass and optical richness and luminosity over two orders of magnitude in cluster mass; the virial mass at fixed richness or luminosity is determined with a precision of {approx} 13% including both statistical and systematic errors. We also constrain the halo concentration parameter and halo bias as a function of cluster mass; both are in good agreement with predictions from N-body simulations of LCDM models. The methods employed here will be applicable to deeper, wide-area optical surveys that aim to constrain the nature of the dark energy, such as the Dark Energy Survey, the Large Synoptic Survey Telescope and space-based surveys.

  11. Residual magnetic field profiles and their current density profiles of coated conductors for fast and slow cut-off current operations

    Energy Technology Data Exchange (ETDEWEB)

    Sun, J.; Taillouli, M.; Hamabe, M.; Watanabe, H.; Chikumoto, N.; Yamaguchi, S. [Chubu University, Kasugai, Aichi (Japan); Shyshkin, O. [V. N. Karazin Kharkiv National University, Kharkov (Ukraine)

    2015-03-15

    Coated conductor is an important candidate for power cable applications due to its high current density. Even for DC power cable transmission, we must study the transport properties of HTS tapes after slow and fast discharge. In order to evaluate relation of the magnetic field with applied current we developed a scanning magnetic field measurements system by employing a Hall probe. This work presents the measurements of the magnetic fields above a coated conductor by varying applied current pattern. In the work, a transport current of 100 A, less than the critical current, is applied to YBCO coated conductor. We measured the residual magnetic field distributions after cut off the transport current with slow and fast operations. The results show differences of the magnetic field profiles and the corresponding current profiles by an inverse solution from the magnetic field measurement between these two operations because of the hysteresis of coated conductor excited by the transport current.

  12. Space charge profiles in low density polyethylene samples containing a permittivity/conductivity gradient

    DEFF Research Database (Denmark)

    Bambery, K.R.; Fleming, R.J.; Holbøll, Joachim

    2001-01-01

    .5×107 V m-1. Current density was also measured as a function of temperature and field. Space charge due exclusively to the temperature gradient was detected, with density of order 0.01 C m-3. The activation energy associated with the transport of electrons through the bulk was calculated as 0.09 e...

  13. Classification of X-ray solar flares regarding their effects on the lower ionosphere electron density profile

    Directory of Open Access Journals (Sweden)

    D. P. Grubor

    2008-06-01

    Full Text Available The classification of X-ray solar flares is performed regarding their effects on the Very Low Frequency (VLF wave propagation along the Earth-ionosphere waveguide. The changes in propagation are detected from an observed VLF signal phase and amplitude perturbations, taking place during X-ray solar flares. All flare effects chosen for the analysis are recorded by the Absolute Phase and Amplitude Logger (AbsPal, during the summer months of 2004–2007, on the single trace, Skelton (54.72 N, 2.88 W to Belgrade (44.85 N, 20.38 E with a distance along the Great Circle Path (GCP D≈2000 km in length.

    The observed VLF amplitude and phase perturbations are simulated by the computer program Long-Wavelength Propagation Capability (LWPC, using Wait's model of the lower ionosphere, as determined by two parameters: the sharpness (β in 1/km and reflection height (H' in km. By varying the values of β and H' so as to match the observed amplitude and phase perturbations, the variation of the D-region electron density height profile Ne(z was reconstructed, throughout flare duration. The procedure is illustrated as applied to a series of flares, from class C to M5 (5×10−5 W/m2 at 0.1–0.8 nm, each giving rise to a different time development of signal perturbation.

    The corresponding change in electron density from the unperturbed value at the unperturbed reflection height, i.e. Ne(74 km=2.16×108 m−3 to the value induced by an M5 class flare, up to Ne(74 km=4×1010 m−3 is obtained. The β parameter is found to range from 0.30–0.49 1/km and the reflection height H' to vary from 74–63 km. The changes in Ne(z during the flares, within height range z=60 to 90 km are determined, as well.

  14. Linear-scaling time-dependent density-functional theory (TDDFT) beyond the Tamm-Dancoff approximation: obtaining efficiency and accuracy with in situ optimised local orbitals

    CERN Document Server

    Zuehlsdorff, Tim J; Payne, Mike C; Haynes, Peter D

    2015-01-01

    We present a solution of the full TDDFT eigenvalue equation in the linear response formalism exhibiting a linear-scaling computational complexity with system size, without relying on the simplifying Tamm-Dancoff approximation (TDA). The implementation relies on representing the occupied and unoccupied subspace with two different sets of in situ optimised localised functions, yielding a very compact and efficient representation of the transition density matrix of the excitation with the accuracy associated with a systematic basis set. The TDDFT eigenvalue equation is solved using a preconditioned conjugate-gradients algorithm that is very memory-efficient. The algorithm is validated on a test molecule and a good agreement with results obtained from standard quantum chemistry packages is found, with the preconditioner yielding a significant improvement in convergence rates. The method developed in this work is then used to reproduce experimental results of the absorption spectrum of bacteriochlorophyll (BChl) i...

  15. Effects of Shewanella putrefaciens on innate immunity and cytokine expression profile upon high stocking density of gilthead seabream specimens.

    Science.gov (United States)

    Cordero, Héctor; Morcillo, Patricia; Meseguer, José; Cuesta, Alberto; Esteban, M Ángeles

    2016-04-01

    High stocking density increases the number of emerging diseases triggering economic losses worldwide. Probiotics provide an effective and natural solution for preventing some diseases through an improvement of innate immune system among others. In the present work dietary administration of the probiotic Shewanella putrefaciens (known as Pdp11) was evaluated under stress by high stocking density after 2 and 4 weeks of administration to gilthead seabream (Sparus aurata) specimens. Results showed an increase in cellular peroxidase and respiratory burst activity as well as a modulation of cytokine profile when Pdp11 was administered to fish reared at high stocking density. Overall, our results showed how Pdp11 is not only able to improve to some extent the cellular and humoral immunity but also to increase the gene expression profile of pro-inflammatory cytokines such as il1b or il6 in response to high stocking density in gilthead seabream. These findings may support the potential use of this probiotic as functional feed against stress in fish farms. Copyright © 2016 Elsevier Ltd. All rights reserved.

  16. Broadening of the Spectral Atomic Lines Analysis in High Density Argon Corona Plasma by Using Voigt Profile

    Science.gov (United States)

    Nur, M.; Bonifaci, N.; Denat, A.; Atrazhev, V. M.

    2015-06-01

    Studies of spectrum emission from high density argon plasma corona has been done. The analysis of the boardening of spectral atomic lines of Ar-I profile has been curried out by using an empirical approximation based on a Voigt profile. Full-width at half-maximum (FWHM) of the spectral-lines of 763.5 nm has been determined from atmospheric pressure until liquid state. The study liquid argon was curried out in a variation of temperature from K to 151.2 K and hydrostatics pressure from 2.1 MPa to 6.4 MPa. These pressure gives the densities N∞ (i.e. density very far from ionization zone) a variation from 1.08 1022 to 2.11 1022 cm-3. FWHM of Voigt approximation (Wv) of the line 763,5 nm of 'Ar I for: the emission lamp very low pressure (Wv = 0,160 nm) and our corona discharge at a pressure of MPa (Wv = 0,67 nm) and at a pressure of 9,5 MPa (Wv = 1,16 nm). In gas, corona plasma has been generated from 0.1 MPa to 9.5 MPa. We found that the broadening spectral line increase by increasing densities both for. the spectral-lines of 763.5 nm and 696.5 nm. We concluded that broadening of spectrum cause of Van der Waals force.

  17. The dynamics of straight vortex filaments in a Bose-Einstein condensate with a Gaussian density profile

    CERN Document Server

    Ruban, V P

    2016-01-01

    The dynamics of interacting quantized vortex filaments in a rotating trapped Bose-Einstein condensate, which is in the Thomas-Fermi regime at zero temperature and described by the Gross-Pitaevskii equation, is considered in the hydrodynamical "anelastic" approximation. In the presence of a smoothly inhomogeneous array of filaments (vortex lattice), a non-canonical Hamiltonian equation of motion is derived for the macroscopically averaged vorticity, with taking into account the spatial non-uniformity of the equilibrium condensate density determined by the trap potential. A minimum of the corresponding Hamiltonian describes a static configuration of deformed vortex lattice against a given density background. The minimum condition is reduced to a vector nonlinear partial differential equation of the second order, for which some approximate and exact solutions are found. It is shown that if the condensate density has an anisotropic Gaussian profile then equation of motion for the averaged vorticity admits solutio...

  18. Model-based Optimization and Feedback Control of the Current Density Profile Evolution in NSTX-U

    Science.gov (United States)

    Ilhan, Zeki Okan

    Nuclear fusion research is a highly challenging, multidisciplinary field seeking contributions from both plasma physics and multiple engineering areas. As an application of plasma control engineering, this dissertation mainly explores methods to control the current density profile evolution within the National Spherical Torus eXperiment-Upgrade (NSTX-U), which is a substantial upgrade based on the NSTX device, which is located in Princeton Plasma Physics Laboratory (PPPL), Princeton, NJ. Active control of the toroidal current density profile is among those plasma control milestones that the NSTX-U program must achieve to realize its next-step operational goals, which are characterized by high-performance, long-pulse, MHD-stable plasma operation with neutral beam heating. Therefore, the aim of this work is to develop model-based, feedforward and feedback controllers that can enable time regulation of the current density profile in NSTX-U by actuating the total plasma current, electron density, and the powers of the individual neutral beam injectors. Motivated by the coupled, nonlinear, multivariable, distributed-parameter plasma dynamics, the first step towards control design is the development of a physics-based, control-oriented model for the current profile evolution in NSTX-U in response to non-inductive current drives and heating systems. Numerical simulations of the proposed control-oriented model show qualitative agreement with the high-fidelity physics code TRANSP. The next step is to utilize the proposed control-oriented model to design an open-loop actuator trajectory optimizer. Given a desired operating state, the optimizer produces the actuator trajectories that can steer the plasma to such state. The objective of the feedforward control design is to provide a more systematic approach to advanced scenario planning in NSTX-U since the development of such scenarios is conventionally carried out experimentally by modifying the tokamak's actuator

  19. Retrieval of effective leaf area index (LAIe) and leaf area density (LAD) profile at individual tree level using high density multi-return airborne LiDAR

    Science.gov (United States)

    Lin, Yi; West, Geoff

    2016-08-01

    As an important canopy structure indicator, leaf area index (LAI) proved to be of considerable implications for forest ecosystem and ecological studies, and efficient techniques for accurate LAI acquisitions have long been highlighted. Airborne light detection and ranging (LiDAR), often termed as airborne laser scanning (ALS), once was extensively investigated for this task but showed limited performance due to its low sampling density. Now, ALS systems exhibit more competing capacities such as high density and multi-return sampling, and hence, people began to ask the questions like-"can ALS now work better on the task of LAI prediction?" As a re-examination, this study investigated the feasibility of LAI retrievals at the individual tree level based on high density and multi-return ALS, by directly considering the vertical distributions of laser points lying within each tree crown instead of by proposing feature variables such as quantiles involving laser point distribution modes at the plot level. The examination was operated in the case of four tree species (i.e. Picea abies, Pinus sylvestris, Populus tremula and Quercus robur) in a mixed forest, with their LAI-related reference data collected by using static terrestrial laser scanning (TLS). In light of the differences between ALS- and TLS-based LAI characterizations, the methods of voxelization of 3D scattered laser points, effective LAI (LAIe) that does not distinguish branches from canopies and unified cumulative LAI (ucLAI) that is often used to characterize the vertical profiles of crown leaf area densities (LADs) was used; then, the relationships between the ALS- and TLS-derived LAIes were determined, and so did ucLAIs. Tests indicated that the tree-level LAIes for the four tree species can be estimated based on the used airborne LiDAR (R2 = 0.07, 0.26, 0.43 and 0.21, respectively) and their ucLAIs can also be derived. Overall, this study has validated the usage of the contemporary high density multi

  20. Space charge profiles in low density polyethylene samples containing a permittivity/conductivity gradient

    DEFF Research Database (Denmark)

    Bambery, K.R.; Fleming, R.J.; Holbøll, Joachim

    2001-01-01

    Laser induced pressure pulse space charge measurements were made on 1.5 mm thick plaques of high purity low density polyethylene equipped with vacuum-evaporated aluminium electrodes. Temperature differences up to 20 °C were maintained across the samples, which were subjected to dc fields up to 1.......5×107 V m-1. Current density was also measured as a function of temperature and field. Space charge due exclusively to the temperature gradient was detected, with density of order 0.01 C m-3. The activation energy associated with the transport of electrons through the bulk was calculated as 0.09 e...

  1. Rapidity Profile of the Initial Energy Density in Heavy-Ion Collisions

    CERN Document Server

    Ozonder, Sener

    2013-01-01

    The rapidity dependence of the initial energy density in heavy-ion collisions is calculated from a three-dimensional McLerran-Venugopalan model (3dMVn) introduced by Lam and Mahlon. This model is infrared safe since global color neutrality is enforced. In this non-boost-invariant framework, the nuclei have non-zero thickness in the longitudinal direction. This results in Bjorken-x dependent unintegrated gluon distribution functions which lead to a rapidity-dependent initial energy density after the collision. The initial energy density and its rapidity dependence are important initial conditions for the quark gluon plasma and its hydrodynamic evolution.

  2. Large Deviation of the Density Profile in the Steady State of the Open Symmetric Simple Exclusion Process

    Science.gov (United States)

    Derrida, B.; Lebowitz, J. L.; Speer, E. R.

    2002-05-01

    We consider an open one dimensional lattice gas on sites i=1,..., N, with particles jumping independently with rate 1 to neighboring interior empty sites, the simple symmetric exclusion process. The particle fluxes at the left and right boundaries, corresponding to exchanges with reservoirs at different chemical potentials, create a stationary nonequilibrium state (SNS) with a steady flux of particles through the system. The mean density profile in this state, which is linear, describes the typical behavior of a macroscopic system, i.e., this profile occurs with probability 1 when N→∞. The probability of microscopic configurations corresponding to some other profile ρ( x), x= i/ N, has the asymptotic form exp[- N F({ ρ})]; F is the large deviation functional. In contrast to equilibrium systems, for which F eq({ ρ}) is just the integral of the appropriately normalized local free energy density, the F we find here for the nonequilibrium system is a nonlocal function of ρ. This gives rise to the long range correlations in the SNS predicted by fluctuating hydrodynamics and suggests similar non-local behavior of F in general SNS, where the long range correlations have been observed experimentally.

  3. The variation of rotation curve shapes as a signature of the effects of baryons on dark matter density profiles

    Science.gov (United States)

    Brook, Chris B.

    2015-12-01

    Rotation curves of galaxies show a wide range of shapes, which can be paramaterized as scatter in Vrot(1 kpc)/Vmax , i.e. the ratio of the rotation velocity measured at 1 kpc and the maximum measured rotation velocity. We examine whether the observed scatter can be accounted for by combining scatters in disc scalelengths, the concentration-halo mass relation, and the M⋆-Mhalo relation. We use these scatters to create model galaxy populations; when housed within dark matter haloes that have universal, Navarro, Frenk & White density profiles, the model does not match the lowest observed values of Vrot(1 kpc)/Vmax and has too little scatter in Vrot(1 kpc)/Vmax compared to observations. By contrast, a model using a mass-dependent dark matter profile, where the inner slope is determined by the ratio of M⋆/Mhalo, produces galaxies with low values of Vrot(1 kpc)/Vmax and a much larger scatter, both in agreement with observation. We conclude that the large observed scatter in Vrot(1 kpc)/Vmax favours density profiles that are significantly affected by baryonic processes. Alternative dark matter core formation models such as self-interacting dark matter may also account for the observed variation in rotation curve shapes, but these observations may provide important constraints in terms of core sizes, and whether they vary with halo mass and/or merger history.

  4. RELATIONSHIPS BETWEEN ANATOMICAL FEATURES AND INTRA-RING WOOD DENSITY PROFILES IN Gmelina arborea APPLYING X-RAY DENSITOMETRY

    Directory of Open Access Journals (Sweden)

    Mario Tomazelo-Filho

    2007-12-01

    Full Text Available Four annual tree-rings (2 of juvenile wood and 2 of mature wood were sampled from fast-growth plantations ofGmelina arborea in two climatic conditions (dry and wet tropical in Costa Rica. Each annual tree-ring was divided in equal parts ina radial direction. For each part, X-ray density as well as vessel percentage, length and width fiber, cell wall thickness and lumendiameter were measured. Wood density and profile patterns of cell dimension demonstrated inconsistency between juvenile andmature wood and climatic conditions. The Pearson correlation matrix showed that intra-ring wood density was positively correlatedwith the cell wall thickness and negatively correlated with vessel percentage, fiber length, lumen diameter and width. The forwardstepwise regressions determined that: (i intra-ring wood density variation could be predicted from 76 to 96% for anatomicalvariation; (ii cell wall thickness was the most important anatomical feature to produce intra-ring wood density variation and (iii thevessel percentage, fiber length, lumen diameter and width were the second most statically significant characteristics to intra-ring wooddensity, however, with low participation of the determination coefficient of stepwise regressions.

  5. Linear-scaling time-dependent density-functional theory beyond the Tamm-Dancoff approximation: Obtaining efficiency and accuracy with in situ optimised local orbitals

    Energy Technology Data Exchange (ETDEWEB)

    Zuehlsdorff, T. J., E-mail: tjz21@cam.ac.uk; Payne, M. C. [Cavendish Laboratory, J. J. Thomson Avenue, Cambridge CB3 0HE (United Kingdom); Hine, N. D. M. [Department of Physics, University of Warwick, Coventry CV4 7AL (United Kingdom); Haynes, P. D. [Department of Materials, Imperial College London, Exhibition Road, London SW7 2AZ (United Kingdom); Department of Physics, Imperial College London, Exhibition Road, London SW7 2AZ (United Kingdom); Thomas Young Centre for Theory and Simulation of Materials, Imperial College London, Exhibition Road, London SW7 2AZ (United Kingdom)

    2015-11-28

    We present a solution of the full time-dependent density-functional theory (TDDFT) eigenvalue equation in the linear response formalism exhibiting a linear-scaling computational complexity with system size, without relying on the simplifying Tamm-Dancoff approximation (TDA). The implementation relies on representing the occupied and unoccupied subspaces with two different sets of in situ optimised localised functions, yielding a very compact and efficient representation of the transition density matrix of the excitation with the accuracy associated with a systematic basis set. The TDDFT eigenvalue equation is solved using a preconditioned conjugate gradient algorithm that is very memory-efficient. The algorithm is validated on a small test molecule and a good agreement with results obtained from standard quantum chemistry packages is found, with the preconditioner yielding a significant improvement in convergence rates. The method developed in this work is then used to reproduce experimental results of the absorption spectrum of bacteriochlorophyll in an organic solvent, where it is demonstrated that the TDA fails to reproduce the main features of the low energy spectrum, while the full TDDFT equation yields results in good qualitative agreement with experimental data. Furthermore, the need for explicitly including parts of the solvent into the TDDFT calculations is highlighted, making the treatment of large system sizes necessary that are well within reach of the capabilities of the algorithm introduced here. Finally, the linear-scaling properties of the algorithm are demonstrated by computing the lowest excitation energy of bacteriochlorophyll in solution. The largest systems considered in this work are of the same order of magnitude as a variety of widely studied pigment-protein complexes, opening up the possibility of studying their properties without having to resort to any semiclassical approximations to parts of the protein environment.

  6. Linear-scaling time-dependent density-functional theory beyond the Tamm-Dancoff approximation: Obtaining efficiency and accuracy with in situ optimised local orbitals

    Science.gov (United States)

    Zuehlsdorff, T. J.; Hine, N. D. M.; Payne, M. C.; Haynes, P. D.

    2015-11-01

    We present a solution of the full time-dependent density-functional theory (TDDFT) eigenvalue equation in the linear response formalism exhibiting a linear-scaling computational complexity with system size, without relying on the simplifying Tamm-Dancoff approximation (TDA). The implementation relies on representing the occupied and unoccupied subspaces with two different sets of in situ optimised localised functions, yielding a very compact and efficient representation of the transition density matrix of the excitation with the accuracy associated with a systematic basis set. The TDDFT eigenvalue equation is solved using a preconditioned conjugate gradient algorithm that is very memory-efficient. The algorithm is validated on a small test molecule and a good agreement with results obtained from standard quantum chemistry packages is found, with the preconditioner yielding a significant improvement in convergence rates. The method developed in this work is then used to reproduce experimental results of the absorption spectrum of bacteriochlorophyll in an organic solvent, where it is demonstrated that the TDA fails to reproduce the main features of the low energy spectrum, while the full TDDFT equation yields results in good qualitative agreement with experimental data. Furthermore, the need for explicitly including parts of the solvent into the TDDFT calculations is highlighted, making the treatment of large system sizes necessary that are well within reach of the capabilities of the algorithm introduced here. Finally, the linear-scaling properties of the algorithm are demonstrated by computing the lowest excitation energy of bacteriochlorophyll in solution. The largest systems considered in this work are of the same order of magnitude as a variety of widely studied pigment-protein complexes, opening up the possibility of studying their properties without having to resort to any semiclassical approximations to parts of the protein environment.

  7. Determination of global plasmaspheric electron density profile by tomographic approach using omega signals and ray tracing

    Science.gov (United States)

    Kimura, I.; Kasahara, Y.; Oya, H.

    2001-07-01

    It has been necessary requirements to determine the global electron density distribution in the plasmasphere with time resolutions, of less than a day. We have provided solutions to this requirement using the wave normal directions, delay time of Omega signals and the in situ electron density observed on-board the Japanese satellite Akebono (Sawada et al., Journal of Geophysical Research 98(11) (1993) 267, Kimura et al., Advance Space Research 15(2) (1995) 103, Advance Space Research 18(6) (1996) 279, Journal of Atmospheric and Solar-Terrestrial Physics 59 (1997) 1569). The present paper is intended to review our earlier studies.

  8. A simple analysis of halo density profiles using gravitational lensing time delays

    OpenAIRE

    2006-01-01

    Gravitational lensing time delays depend upon the Hubble constant and the density distribution of the lensing galaxies. This allows one to either model the lens and estimate the Hubble constant, or to use a prior on the Hubble constant from other studies and investigate what the preferred density distribution is. Some studies have required compact dark matter halos (constant M/L ratio) in order to reconcile gravitational lenses with the HST/WMAP value of the Hubble constant (72 +/- 8 km/s /Mp...

  9. Cross-correlation Weak Lensing of SDSS galaxy Clusters II: Cluster Density Profiles and the Mass--Richness Relation

    CERN Document Server

    Johnston, David E; Wechsler, Risa H; Rozo, Eduardo; Koester, Benjamin P; Frieman, Joshua A; McKay, Timothy A; Evrard, August E; Becker, Matthew R; Annis, James

    2007-01-01

    We interpret and model the statistical weak lensing measurements around 130,000 groups and clusters of galaxies in the Sloan Digital Sky Survey presented by Sheldon et al. 2007 (Paper I). We present non-parametric inversions of the 2D shear profiles to the mean 3D cluster density and mass profiles in bins of both optical richness and cluster i-band luminosity. We correct the inferred 3D profiles for systematic effects, including non-linear shear and the fact that cluster halos are not all precisely centered on their brightest galaxies. We also model the measured cluster shear profile as a sum of contributions from the brightest central galaxy, the cluster dark matter halo, and neighboring halos. We infer the relations between mean cluster virial mass and optical richness and luminosity over two orders of magnitude in cluster mass; the virial mass at fixed richness or luminosity is determined with a precision of 13% including both statistical and systematic errors. We also constrain the halo concentration para...

  10. Gene expression profiling in human peripheral blood mononuclear cells using high-density filter-based cDNA microarrays.

    Science.gov (United States)

    Walker, J; Rigley, K

    2000-05-26

    Microarray technology has provided the ability to analyse the expression profiles for thousands of genes in parallel. The need for highly specialised equipment to use certain types of microarrays has restricted the application of this technology to a small number of dedicated laboratories. High-density filter-based cDNA microarrays provide a low-cost option for performing high-throughput gene expression analysis. We have used a model system in which filter-based cDNA microarrays representing over 4000 known human genes were used to monitor the kinetics of gene expression in human peripheral blood mononuclear cells (PBMCs) stimulated with phytohaemagluttinin (PHA). Using software-based cluster analysis, we identified 104 genes that altered in expression levels in response to PHA stimulation of PBMCs and showed that there was a considerable overlap between genes with similar temporal expression profiles and similar functional roles. Comparison of microarray quantitation with quantitative PCR showed almost identical expression profiles for a number of genes. Coupled with the fact that our findings are in agreement with a large number of independent observations, we conclude that the use of filter-based cDNA microarrays is a valid and accurate method for high-throughput gene expression profiling.

  11. Assessment risk of osteoporosis in Chinese people: relationship among body mass index, serum lipid profiles, blood glucose, and bone mineral density

    Directory of Open Access Journals (Sweden)

    Cui RT

    2016-07-01

    Full Text Available Rongtao Cui,1 Lin Zhou,2 Zuohong Li,2 Qing Li,2 Zhiming Qi,2 Junyong Zhang3 1Department of Orthopedic and Trauma Surgery, Surgical Research, Duisburg-Essen University Hospital, Essen, Germany; 2Department of Orthopedics, Dalian Central Hospital, Dalian, 3Department of Gastroenterology, Shandong Provincial Hospital, Jinan, People’s Republic of China Objective: The aim of our study was to investigate the relationship among age, sex, body mass index (BMI, serum lipid profiles, blood glucose (BG, and bone mineral density (BMD, making an assessment of the risk of osteoporosis.Materials and methods: A total of 1,035 male and 3,953 female healthy volunteers (aged 41–95 years were recruited by an open invitation. The basic information, including age, sex, height, weight, waistline, hipline, menstrual cycle, and medical history, were collected by a questionnaire survey and physical examination. Serum lipid profiles, BG, postprandial blood glucose, and glycosylated hemoglobin were obtained after 12 hours fasting. BMD in lumbar spine was measured by dual-energy X-ray absorptiometry scanning.Results: The age-adjusted BMD in females was significantly lower than in males. With aging, greater differences of BMD distribution exist in elderly females than in males (P<0.001, and the fastigium of bone mass loss was in the age range from 51 to 55 in females and from 61 to 65 years in males. After adjustment for sex, there were significant differences in BMD among BMI-stratified groups in both males and females. The subjects with a BMI of <18.5 had a higher incidence of osteoporosis than BMI ≥18.5 in both sexes. BMD in type 2 diabetes mellitus with a BG of >7.0 mmol/L was lower than in people with BG of ≤7.0 mmol/L (P<0.001. People with serum high-density lipoprotein cholesterol levels of ≥1.56 mmol/L had a greater prevalence of osteoporosis compared with high-density lipoprotein cholesterol ≤1.55 mmol/L. Logistic regression with odds ratios showed that

  12. Utilization of α-olefins obtained by pyrolysis of waste high density polyethylene to synthesize α-olefin-succinic-anhydride based cold flow improvers

    Institute of Scientific and Technical Information of China (English)

    Norbert MISKOLCZI; Richard SAGI; László BARTHA; Lívia FORCEK

    2009-01-01

    A new route of utilization of α-olefin rich hydrocarbon fractions obtained by waste polymer pyrolysis was investigated. α-olefin-succinic-anhydride intermediate-based pour point depressant additives for diesel fuel were synthesized, in which reactions needed α-olefins were obtained by pyrolysis of waste high-density polyethylene (HDPE). Fraction of α-olefins was produced by the de-polymerization of plastic waste in a tube reactor at 500℃ in the absence of catalysts and air. C17~22 range of mixtures of olefins and paraffins were separated for synthesis and then, these hydrocarbons were reacted with maleic-anhydride (MA) for formation of α-olefin-succinic-anhydride intermediates. The olefin-rich hydrocarbon fraction contained approximately 60% of olefins, including 90%~95% α-olefins. Other intermediates were produced in the same way by using commercial C20 α-olefin instead of C17~22 olefin mixture. The two different experimental intermediates with number average molecular weights of 1850g/mol and 1760g/mol were reacted with different alcohols: 1-butanol, 1-hexanol, 1-octanol, i-butanol, and c-hexanol to produce their ester derivatives. The synthesized ten experimental pour point depressants were added in different concentrations to conventional diesel fuel, which had no other additive content before. The structure and efficiency of experimental additives were followed by different standardized and non-standardized methods. Results showed that the experimental additives on the basis of the product of waste pyrolysis were able to decrease not only the pour but also the cloud point and cold filter plugging point (CFPP) of diesel fuel, whose effects could be observed even if the concentration of additives was low. Furthermore, all additives had anti-wear and anti-friction effects in diesel fuel.

  13. Mathematical modeling of velocity and number density profiles of particles across the flame propagation through a micro-iron dust cloud.

    Science.gov (United States)

    Bidabadi, Mehdi; Haghiri, Ali; Rahbari, Alireza

    2010-04-15

    In this study, an attempt has been made to analytically investigate the concentration and velocity profiles of particles across flame propagation through a micro-iron dust cloud. In the first step, Lagrangian particle equation of motion during upward flame propagation in a vertical duct is employed and then forces acting upon the particle, such as thermophoretic force (resulted from the temperature gradient), gravitation and buoyancy are introduced; and consequently, the velocity profile as a function of the distance from the leading edge of the combustion zone is extracted. In the resumption, a control volume above the leading edge of the combustion zone is considered and the change in the particle number density in this control volume is obtained via the balance of particle mass fluxes passing through it. This study explains that the particle concentration at the leading edge of the combustion zone is more than the particle agglomeration in a distance far from the flame front. This increase in the particle aggregation above the combustion zone has a remarkable effect on the lower flammability limits of combustible particle cloud. It is worth noticing that the velocity and particle concentration profiles show a reasonable compatibility with the experimental data.

  14. Structure formation in parallel ion flow and density profiles by cross-ferroic turbulent transport in linear magnetized plasma

    Science.gov (United States)

    Kobayashi, T.; Inagaki, S.; Kosuga, Y.; Sasaki, M.; Nagashima, Y.; Yamada, T.; Arakawa, H.; Kasuya, N.; Fujisawa, A.; Itoh, S.-I.; Itoh, K.

    2016-10-01

    In this paper, we show the direct observation of the parallel flow structure and the parallel Reynolds stress in a linear magnetized plasma, in which a cross-ferroic turbulence system is formed [Inagaki et al., Sci. Rep. 6, 22189 (2016)]. It is shown that the parallel Reynolds stress induced by the density gradient driven drift wave is the source of the parallel flow structure. Moreover, the generated parallel flow shear by the parallel Reynolds stress is found to drive the parallel flow shear driven instability D'Angelo mode, which coexists with the original drift wave. The excited D'Angelo mode induces the inward particle flux, which seems to help in maintaining the peaked density profile.

  15. Core and Wing Densities of Asymmetric Coronal Spectral Profiles: Implications for the Mass Supply of the Solar Corona

    Science.gov (United States)

    Patsourakos, S.; Klimchuk, J. A.; Young, P. R.

    2014-01-01

    Recent solar spectroscopic observations have shown that coronal spectral lines can exhibit asymmetric profiles, with enhanced emissions at their blue wings. These asymmetries correspond to rapidly upflowing plasmas at speeds exceeding approximately equal to 50 km per sec. Here, we perform a study of the density of the rapidly upflowing material and compare it with that of the line core that corresponds to the bulk of the plasma. For this task, we use spectroscopic observations of several active regions taken by the Extreme Ultraviolet Imaging Spectrometer of the Hinode mission. The density sensitive ratio of the Fe(sub XIV) lines at 264.78 and 274.20 Angstroms is used to determine wing and core densities.We compute the ratio of the blue wing density to the core density and find that most values are of order unity. This is consistent with the predictions for coronal nanoflares if most of the observed coronal mass is supplied by chromospheric evaporation driven by the nanoflares. However, much larger blue wing-to-core density ratios are predicted if most of the coronal mass is supplied by heated material ejected with type II spicules. Our measurements do not rule out a spicule origin for the blue wing emission, but they argue against spicules being a primary source of the hot plasma in the corona. We note that only about 40% of the pixels where line blends could be safely ignored have blue wing asymmetries in both Fe(sub XIV) lines. Anticipated sub-arcsecond spatial resolution spectroscopic observations in future missions could shed more light on the origin of blue, red, and mixed asymmetries.

  16. Density profile characterization and modeling at Paranal and Armazones 2k sites

    Directory of Open Access Journals (Sweden)

    Marín Julio C.

    2017-01-01

    Full Text Available The Cherenkov Telescope Array (CTA in the southern hemisphere will be installed at Armazones 2k site in northern Chile. Scarce atmospheric observations are available in the region, particularly radiosonde data. This study analyzes radiosondes launched at Paranal observatory, located at about 21 km from the CTA site, from 24 October and 4 November 2011, to understand the behavior of density in the atmosphere near the CTA site. High-resolution numerical simulations with the Weather Research and Forecasting (WRF model are validated with Paranal radiosondes to quantify its ability to represent the atmospheric conditions in the region. In addition, the seasonal and diurnal evolution of atmospheric density at the CTA site were studied during 2011 using the high-resolution weather forecasts from the WRF model.

  17. Vortex line density in counterflowing He II with laminar and turbulent normal fluid velocity profiles

    CERN Document Server

    Baggaley, A W

    2013-01-01

    Superfluid helium is an intimate mixture of a viscous normal fluid, with continuous vorticity, and an inviscid superfluid, where vorticity is constrained to thin, stable topological defects. One mechanism to generate turbulence in this system is through the application of a heat flux, so called thermal counterflow. Of particular interest is how turbulence in the superfluid responds to both a laminar and turbulent normal fluid in the presence of walls. We model superfluid vortex lines as reconnecting space curves with fixed circulation, and consider both laminar (Poiseuille) and turbulent normal fluid flows in a channel configuration. Using high resolution numerical simulations we show that turbulence in the normal fluid sustains a notably higher vortex line density than a laminar flow with the same mean flow rate. We exam Vinen's relation, $\\sqrt{L}=\\gamma v_{ns}$, between the steady state vortex line density $L$ and the counterflow velocity $v_{ns}$. Our results support the hypothesis that transition to turb...

  18. One-dimensional transport of interacting particles: currents, density profiles, phase diagrams, and symmetries.

    Science.gov (United States)

    Dierl, Marcel; Einax, Mario; Maass, Philipp

    2013-06-01

    Driven lattice gases serve as canonical models for investigating collective transport phenomena and properties of nonequilibrium steady states. Here we study one-dimensional transport with nearest-neighbor interactions both in closed bulk systems and in open channels coupled to two particle reservoirs at the ends of the channel. For the widely employed Glauber rates we derive an exact current-density relation in the bulk for unidirectional hopping. An approach based on time-dependent density functional theory provides a good description of the kinetics. For open systems, the system-reservoir couplings are shown to have a striking influence on boundary-induced phase diagrams. The role of particle-hole symmetry is discussed, and its consequence for the topology of the phase diagrams. It is furthermore demonstrated that systems with weak bias can be mapped onto systems with unidirectional hopping.

  19. Recreational football improves bone mineral density and bone turnover marker profile in elderly men

    DEFF Research Database (Denmark)

    Helge, E W; Andersen, T R; Schmidt, J F;

    2014-01-01

    This study examined the effect of recreational football and resistance training on bone mineral density (BMD) and bone turnover markers (BTMs) in elderly men. Twenty-six healthy sedentary men (age 68.2 ± 3.2 years) were randomized into three groups: football (F; n = 9) and resistance training (R; n...... training had no effect. The anabolic response may be due to increased bone turnover, especially improved bone formation....

  20. Differential gene expression profiles in foetal skin of Rex rabbits with different wool density

    Directory of Open Access Journals (Sweden)

    L. Liu

    2016-09-01

    Full Text Available This study investigated the mechanisms controlling hair follicle development in the Rex rabbit. The Agilent rabbit gene expression microarray was used to determine differentially expressed genes in Rex rabbit foetuses with different wool densities. The expression patterns of selected differentially-expressed genes were further investigated by quantitative real-time PCR. Compared to low wool density rabbits, 1342 differentially expressed probes were identified in high wool density rabbits, including 950 upregulated probes and 392 downregulated probes. Gene ontology analysis revealed that the most upregulated differentially expressed probes belonged to receptors and the most downregulated differentially expressed probes belonged to DNA binding molecules. Kyoto Encyclopedia of Genes and Genomes pathway analysis revealed that the differentially expressed probes were mainly involved in the sonic hedgehog (Shh and Eph signalling pathways. The results also suggest that transforming growth factor-beta 1, growth hormone receptor, and the keratin-associated protein 6.1 genes, as well as the Shh and Eph signalling pathways, may be involved in the regulation of hair follicle developmental in Rex rabbits.

  1. Similar Spectral Power Densities Within the Schumann Resonance and a Large Population of Quantitative Electroencephalographic Profiles: Supportive Evidence for Koenig and Pobachenko.

    Directory of Open Access Journals (Sweden)

    Kevin S Saroka

    Full Text Available In 1954 and 1960 Koenig and his colleagues described the remarkable similarities of spectral power density profiles and patterns between the earth-ionosphere resonance and human brain activity which also share magnitudes for both electric field (mV/m and magnetic field (pT components. In 2006 Pobachenko and colleagues reported real time coherence between variations in the Schumann and brain activity spectra within the 6-16 Hz band for a small sample. We examined the ratios of the average potential differences (~3 μV obtained by whole brain quantitative electroencephalography (QEEG between rostral-caudal and left-right (hemispheric comparisons of 238 measurements from 184 individuals over a 3.5 year period. Spectral densities for the rostral-caudal axis revealed a powerful peak at 10.25 Hz while the left-right peak was 1.95 Hz with beat-differences of ~7.5 to 8 Hz. When global cerebral measures were employed, the first (7-8 Hz, second (13-14 Hz and third (19-20 Hz harmonics of the Schumann resonances were discernable in averaged QEEG profiles in some but not all participants. The intensity of the endogenous Schumann resonance was related to the 'best-of-fitness' of the traditional 4-class microstate model. Additional measurements demonstrated real-time coherence for durations approximating microstates in spectral power density variations between Schumann frequencies measured in Sudbury, Canada and Cumiana, Italy with the QEEGs of local subjects. Our results confirm the measurements reported by earlier researchers that demonstrated unexpected similarities in the spectral patterns and strengths of electromagnetic fields generated by the human brain and the earth-ionospheric cavity.

  2. Citrus reticulata’s Peels Modulate Blood Cholesterol Profile and IncreaseBone Density of Ovariectomized Rats

    Directory of Open Access Journals (Sweden)

    Rosa Adelina

    2015-11-01

    Full Text Available Hormon Replacement Therapy is a common therapy for estrogen deficiency but in other side it will increase the risk of cardiovascular disease. Another alternative therapy which relatively more safe is using phytoestrogen. The Citrus reticulata’s peel contain flavanone and polimethoxyflavone which are suspected to give estrogenic effect, therefore it is potential to be used as phytoestrogen.The purpose of this study was to examine the estrogenic effect of Citrus reticulata’s peel extract in modulation of bone density and blood cholesterol profile of ovariectomized rats (OVX, an animal model of postmenopausal osteoporosis. Thirty six 7-weeks-old female Sprague Dawley rats were assigned to six groups: a SO group, an OVX group, an OVX+CMCNa group, an OVX+extract dose 500 mg/kgBW group, an OVX+extract dose 1000 mg/kgBW group, and an OVX+estradiol group. After 7 weeks, the rats were killed then blood and femoral were collected immediately. The rontgenogram indicated that extract and estradiol administration increase the bone density. And the data analysis with Oneway ANOVA test ,followed by Shceffé test (P 0.05 showed that extract can improve blood cholesterol profile in dose depend manner. These results suggest a possible role of Citrus reticulata’s peel extract as women’s health agent because of its beneficial effects on bone and lipids.

  3. Density profile in shock wave fronts of partially ionized xenon plasmas

    CERN Document Server

    Reinholz, H; Morozov, I; Mintsev, V; Zaparoghets, Y; Fortov, V; Wierling, A

    2003-01-01

    Results for the reflection coefficient of shock-compressed dense xenon plasmas at pressures of 1.6-20 GPa and temperatures around 30 000 K are interpreted. In addition to former experiments using laser beams with lambda = 1.06 mu m, measurements at lambda = 0.694 mu m have been performed recently. Reflectivities typical for metallic systems are found at high densities. Besides free carriers, the theoretical description also takes into account the influence of the neutral component of the plasma on the reflectivity. A consistent description of the measured reflectivities is achieved only if a finite width of the shock wave front is considered.

  4. Density profile evolution and nonequilibrium effects in partial and full spreading measurements of surface diffusion

    DEFF Research Database (Denmark)

    Nikunen, P.; Vattulainen, Ilpo Tapio; Ala-Nissila, T.

    2001-01-01

    in D-C(theta) depend on the initial density gradient and the initial state from which the spreading starts. To this end, we carry out extensive Monte Carlo simulations for a lattice-gas model of the O/W(110) system. Studies of submonolayer spreading from an initially ordered p(2x1) phase at theta = 1....../2 reveal that the spreading and diffusion rates in directions parallel and perpendicular to rows of oxygen atoms are significantly different within the ordered phase. Aside from this effect, we find that the degree of ordering in the initial phase has a relatively small impact on the overall behavior of D...

  5. Density and current profiles in Uq (A2(1)) zero range process

    Science.gov (United States)

    Kuniba, A.; Mangazeev, V. V.

    2017-09-01

    The stochastic R matrix for Uq (An(1)) introduced recently gives rise to an integrable zero range process of n classes of particles in one dimension. For n = 2 we investigate how finitely many first class particles fixed as defects influence the grand canonical ensemble of the second class particles. By using the matrix product stationary probabilities involving infinite products of q-bosons, exact formulas are derived for the local density and current of the second class particles in the large volume limit.

  6. Measurements of Electron Density Profiles of Plasmas Produced by Nike KrF Laser for Laser Plasma Instability (LPI) Research

    Science.gov (United States)

    Oh, Jaechul; Weaver, J. L.; Obenschain, S. P.; Schmitt, A. J.; Kehne, D. M.; Karasik, M.; Chan, L.-Y.; Serlin, V.; Phillips, L.

    2013-10-01

    Knowing spatial profiles of electron density (ne) in the underdense coronal region (n Nike LPI experiment, a side-on grid imaging refractometer (GIR) was deployed for measuring the underdense plasma profiles. Plasmas were produced from flat CH targets illuminated by Nike KrF laser with total energies up to 1 kJ of 0.5 ~ 1 nsec FWHM pulses. The GIR resolved ne up to 3 ×1021 /cm3 in space taking 2D snapshot images of probe laser (λ = 263 nm, Δt = 10 ps) beamlets (50 μm spacing) refracted by the plasma at a selected time during the laser illumination. The individual beamlet transmittances were also measured for Te estimation. Time-resolved spectrometers with an absolute-intensity-calibrated photodiode array and a streak camera simultaneously detected light emission from the plasma in spectral ranges relevant to Raman (SRS) and two plasmon decay instabilities. The measured spatial profiles are compared with simulation results from the FAST3D radiation hydrocode and their effects on the LPI observations are investigated. Work supported by DoE/NNSA and performed at Naval Research Laboratory.

  7. Computational modeling of Krypton gas puffs with tailored mass density profiles on Z

    Energy Technology Data Exchange (ETDEWEB)

    Jennings, C. A.; Ampleford, D. J.; Lamppa, D. C.; Hansen, S. B.; Jones, B.; Harvey-Thompson, A. J.; Jobe, M.; Strizic, T.; Reneker, J.; Rochau, G. A.; Cuneo, M. E. [Sandia National Laboratories, PO Box 5800, Albuquerque, New Mexico 87185 (United States)

    2015-05-15

    Large diameter multi-shell gas puffs rapidly imploded by high current (∼20 MA, ∼100 ns) on the Z generator of Sandia National Laboratories are able to produce high-intensity Krypton K-shell emission at ∼13 keV. Efficiently radiating at these high photon energies is a significant challenge which requires the careful design and optimization of the gas distribution. To facilitate this, we hydrodynamically model the gas flow out of the nozzle and then model its implosion using a 3-dimensional resistive, radiative MHD code (GORGON). This approach enables us to iterate between modeling the implosion and gas flow from the nozzle to optimize radiative output from this combined system. Guided by our implosion calculations, we have designed gas profiles that help mitigate disruption from Magneto-Rayleigh–Taylor implosion instabilities, while preserving sufficient kinetic energy to thermalize to the high temperatures required for K-shell emission.

  8. Association of Maternal Antiangiogenic Profile at Birth With Early Postnatal Loss of Microvascular Density in Offspring of Hypertensive Pregnancies

    Science.gov (United States)

    Yu, Grace Z.; Aye, Christina Y.L.; Lewandowski, Adam J.; Davis, Esther F.; Khoo, Cheen P.; Newton, Laura; Yang, Cheng T.; Al Haj Zen, Ayman; Simpson, Lisa J.; O’Brien, Kathryn; Cook, David A.; Granne, Ingrid; Kyriakou, Theodosios; Channon, Keith M.; Watt, Suzanne M.

    2016-01-01

    Offspring of hypertensive pregnancies are more likely to have microvascular rarefaction and increased blood pressure in later life. We tested the hypothesis that maternal angiogenic profile during a hypertensive pregnancy is associated with fetal vasculogenic capacity and abnormal postnatal microvascular remodeling. Infants (n=255) born after either hypertensive or normotensive pregnancies were recruited for quantification of postnatal dermal microvascular structure at birth and 3 months of age. Vasculogenic cell potential was assessed in umbilical vein endothelial cells from 55 offspring based on in vitro microvessel tube formation and proliferation assays. Maternal angiogenic profile (soluble fms-like tyrosine kinase-1, soluble endoglin, vascular endothelial growth factor, and placental growth factor) was measured from postpartum plasma samples to characterize severity of pregnancy disorder. At birth, offspring born after hypertensive pregnancy had similar microvessel density to those born after a normotensive pregnancy, but during the first 3 postnatal months, they had an almost 2-fold greater reduction in total vessel density (−17.7±16.4% versus −9.9±18.7%; P=0.002). This postnatal loss varied according to the vasculogenic capacity of the endothelial cells of the infant at birth (r=0.49; P=0.02). The degree of reduction in both in vitro and postnatal in vivo vascular development was proportional to levels of antiangiogenic factors in the maternal circulation. In conclusion, our data indicate that offspring born to hypertensive pregnancies have reduced vasculogenic capacity at birth that predicts microvessel density loss over the first 3 postnatal months. Degree of postnatal microvessel reduction is proportional to levels of antiangiogenic factors in the maternal circulation at birth. PMID:27456522

  9. The Co-Evolution of Total Density Profiles and Central Dark Matter Fractions in Simulated Early-Type Galaxies

    CERN Document Server

    Remus, Rhea-Silvia; Naab, Thorsten; Burkert, Andreas; Hirschmann, Michaela; Hoffmann, Tadziu L; Johansson, Peter H

    2016-01-01

    We present evidence from cosmological hydrodynamical simulations for a co-evolution of the slope of the total (dark and stellar) mass density profiles, gamma_tot, and the dark matter fractions within the half-mass radius, f_DM, in early-type galaxies. The relation can be described as gamma_tot = A f_DM + B and holds for all systems at all redshifts. We test different feedback models and find that the general trend is independent of the assumed feedback processes and is set by the decreasing importance of dissipative processes towards lower redshifts and for more massive systems. Early-type galaxies are smaller, more concentrated, have lower dark matter fractions and steeper total density slopes at high redshifts and at lower masses for a given redshift. The values for A and B change distinctively with the assumed feedback model, and thus this relation can be used as a test for feedback models. A similar correlation exists between gamma_tot and the stellar mass surface density Sigma_*. The model with weak stel...

  10. Profile of cortisol, glycaemia, and blood parameters of American Bullfrog tadpoles Lithobates catesbeianus exposed to density and hypoxia stressors

    Directory of Open Access Journals (Sweden)

    Patricia C. Teixeira

    2012-12-01

    Full Text Available The aim of this study was to evaluate alterations to the physiological profile (cortisol, glycaemia, and blood parameters of Lithobates catesbeianus caused by the stressors density and hypoxia. The organisms were in the prometamorphosis stage and exposed to different tadpole densities: 1 tadpole/L (T1, 5 tadpoles/L (T2, and 10 tadpoles/L (T3 for 12 days. The blood was collected through the rupture of the caudal blood vessel and collected under normoxia (immediate collection and hypoxia (after 15 minutes of air exposure conditions. Cortisol levels rose on the fourth and eighth days of treatment and returned to basal levels by the end of the experiment. The stressor mechanisms tested did not affect glycaemia. White blood cells (total number of lymphocytes, neutrophils, and eosinophils showed a significant difference at the twelfth day of the experiment when compared with the start of the experiment. We concluded that, under controlled conditions, a density of up to 10 tadpoles/L and air exposure for 15 minutes did not cause harmful physiological alterations during the experimental period. The answer to these stressors maybe was in another hormonal level (corticosterone.

  11. A method for evaluating models that use galaxy rotation curves to derive the density profiles

    CERN Document Server

    de Almeida, Álefe O F; Rodrigues, Davi C

    2016-01-01

    There are some approaches, either based on General Relativity (GR) or modified gravity, that use galaxy rotation curves to derive the matter density of the corresponding galaxy, and this procedure would either indicate a partial or a complete elimination of dark matter in galaxies. Here we review these approaches, clarify the difficulties on this inverted procedure, present a method for evaluating them, and use it to test two specific approaches that are based on GR: the Cooperstock-Tieu (CT) and the Balasin-Grumiller (BG) approaches. Using this new method, we find that neither of the tested approaches can satisfactorily fit the observational data without dark matter. The CT approach results can be significantly improved if some dark matter is considered, while for the BG approach no usual dark matter halo can improve its results.

  12. A method for evaluating models that use galaxy rotation curves to derive the density profiles

    Science.gov (United States)

    de Almeida, Álefe O. F.; Piattella, Oliver F.; Rodrigues, Davi C.

    2016-11-01

    There are some approaches, either based on General Relativity (GR) or modified gravity, that use galaxy rotation curves to derive the matter density of the corresponding galaxy, and this procedure would either indicate a partial or a complete elimination of dark matter in galaxies. Here we review these approaches, clarify the difficulties on this inverted procedure, present a method for evaluating them, and use it to test two specific approaches that are based on GR: the Cooperstock-Tieu (CT) and the Balasin-Grumiller (BG) approaches. Using this new method, we find that neither of the tested approaches can satisfactorily fit the observational data without dark matter. The CT approach results can be significantly improved if some dark matter is considered, while for the BG approach no usual dark matter halo can improve its results.

  13. Exact nonlinear analytic Vlasov-Maxwell tangential equilibria with arbitrary density and temperature profiles

    CERN Document Server

    Mottez, F

    2003-01-01

    The tangential layers are characterized by a bulk plasma velocity and a magnetic field that are perpendicular to the gradient direction. They have been extensively described in the frame of the Magneto-Hydro-Dynamic (MHD) theory. But the MHD theory does not look inside the transition region if the transition has a size of a few ion gyroradii. A series of kinetic tangential equilibria, valid for a collisionless plasma is presented. These equilibria are exact analytical solutions of the Maxwell-Vlasov equations. The particle distribution functions are sums of an infinite number of elementary functions parametrized by a vector potential. Examples of equilibria relevant to space plasmas are shown. A model for the deep and sharp density depletions observed in the auroral zone of the Earth is proposed. Tangential equilibria are also relevant for the study of planetary environments and of remote astrophysical plasmas.

  14. Global SAXS data analysis for multilamellar vesicles: Evolution of the scattering density profile (SDP) model

    CERN Document Server

    Heftberger, Peter; Heberle, Frederick A; Pan, Jianjun; Rappolt, Michael; Amenitsch, Heinz; Kucerka, Norbert; Katsaras, John; Pabst, Georg

    2013-01-01

    We adapted the highly successful scattering density pro?le (SDP) model, which is used to jointly analyze small angle x-ray and neutron scattering data from unilamellar vesicles, for use with data from fully hydrated, liquid crystalline multilamellar vesicles (MLVs). By using a genetic algorithm, this new method is capable of providing high resolution structural information, as well as determining bilayer elastic bending fluctuations from standalone x-ray data. Important structural parameters, such as bilayer thickness and area per lipid were determined for a series of saturated and unsaturated lipids, as well as binary mixtures with cholesterol. Results are in good agreement with previously reported SDP data, which used both neutron and x-ray data. The addition of deuterated and non-deuterated MLV neutron data to the analysis improved lipid backbone information, but did not improve, within experimental uncertainties, the structural information regarding bilayer thickness and area per lipid.

  15. Time Ordering Effects on Hydrogen Zeeman-Stark Line Profiles in Low-Density Magnetized Plasmas

    Directory of Open Access Journals (Sweden)

    J. Rosato

    2010-01-01

    Full Text Available Stark broadening of hydrogen lines is investigated in low-density magnetized plasmas, at typical conditions of magnetic fusion experiments. The role of time ordering is assessed numerically, by using a simulation code accounting for the evolution of the microscopic electric field generated by the charged particles moving at the vicinity of the atom. The Zeeman effect due to the magnetic field is also retained. Lyman lines with a low principal quantum number n are first investigated, for an application to opacity calculations; next Balmer lines with successively low and high principal quantum numbers are considered for diagnostic purposes. It is shown that neglecting time ordering results in a dramatic underestimation of the Stark effect on the low-n lines. Another conclusion is that time ordering becomes negligible only when ion dynamics effects vanish, as shown in the case of high-n lines.

  16. Safety profile of subjects treated to very low low-density lipoprotein cholesterol levels (JUPITER).

    Science.gov (United States)

    Everett, Brendan M; Mora, Samia; Glynn, Robert J; MacFadyen, Jean; Ridker, Paul M

    2014-12-01

    Recent US guidelines expand the indications for high-intensity statin therapy, yet data on the safety of attaining very low-density lipoprotein cholesterol (LDL-C) levels are scarce. Among 16,304 participants in the Justification for the Use of Statins in Prevention: An Intervention Trial Evaluating Rosuvastatin (JUPITER) with on-treatment LDL-C levels, we identified 767 who did and 7,387 who did not achieve LDL-C JUPITER, achieving LDL-C levels <30 mg/dl with high-intensity statin therapy appeared to be generally well tolerated but associated with certain adverse events, including more physician-reported diabetes, hematuria, hepatobiliary disorders, and insomnia. These data may guide the monitoring of patients on intensive statin therapy and adverse events in trials of therapies that lead to very low LDL-C levels.

  17. Ozone profiles obtained by DIAL technique at Maïdo Observatory in La Réunion Island: comparisons with ECC ozone-sondes, ground-based FTIR spectrometer and microwave radiometer measurements

    OpenAIRE

    Portafaix T.; Godin-Beekmann S.; Payen G.; de Mazière M.; Langerock B.; Fernandez S; Posny F.; Cammas J.P.; Metzger J. M.; Bencherif H.; Vigouroux C.; Marquestaut N.

    2016-01-01

    International audience; A DIAL lidar system performing stratospheric ozone profile measurements from 15 to 45 km is installed at Reunion Island (southwest of Indian Ocean). The purpose of this communication is to present this DIAL system mounted now at the new Maïdo Observatory since February 2013, and the ozone profile retrieval. The first stratospheric ozone profiles obtained during 2013 and 2014 will be presented and discussed. Inter-comparison and differences observed with other high vert...

  18. Quantitative T1 and proton density mapping with direct calculation of radiofrequency coil transmit and receive profiles from two-point variable flip angle data.

    Science.gov (United States)

    Baudrexel, Simon; Reitz, Sarah C; Hof, Stephanie; Gracien, René-Maxime; Fleischer, Vinzenz; Zimmermann, Hilga; Droby, Amgad; Klein, Johannes C; Deichmann, Ralf

    2016-03-01

    Quantitative T1 mapping of brain tissue is frequently based on the variable flip angle (VFA) method, acquiring spoiled gradient echo (GE) datasets at different excitation angles. However, accurate T1 calculation requires a knowledge of the sensitivity profile B1 of the radiofrequency (RF) transmit coil. For an additional derivation of proton density (PD) maps, the receive coil sensitivity profile (RP) must also be known. Mapping of B1 and RP increases the experiment duration, which may be critical when investigating patients. In this work, a method is presented for the direct calculation of B1 and RP from VFA data. Thus, quantitative maps of T1 , PD, B1 and RP can be obtained from only two spoiled GE datasets. The method is based on: (1) the exploitation of the linear relationship between 1/PD and 1/T1 in brain tissue and (2) the assumption of smoothly varying B1 and RP, so that a large number of data points can be fitted across small volume elements where B1 and RP are approximately constant. The method is tested and optimized on healthy subjects. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  19. Measuring one-dimensional and two-dimensional impurity density profiles on TEXTOR using combined charge exchange-beam emission spectroscopy and ultrasoft x-ray tomography

    Science.gov (United States)

    De Bock, M.; Jakubowska, K.; Hellermann, M. von; Jaspers, R.; Donné, A. J. H.; Shmaenok, L.

    2004-10-01

    Two techniques are presented that allow us to measure impurity density profiles in the TEXTOR tokamak plasma. The one-dimensional profiles are gathered by charge exchange recombination spectroscopy (CXRS) in combination with beam emission spectroscopy (BES). Combining CXRS and BES eliminate the need for absolute calibration. For two-dimensional profiles an ultrasoft x-ray tomography system has been developed. The system is spectrally resolved and produces local emissivity profiles of several ionization stages of impurities. Both systems are presently being commissioned. They are complementary and give an insight into the impurity distribution and transport in plasmas.

  20. Is It Possible To Obtain Coupled Cluster Quality Energies at near Density Functional Theory Cost? Domain-Based Local Pair Natural Orbital Coupled Cluster vs Modern Density Functional Theory.

    Science.gov (United States)

    Liakos, Dimitrios G; Neese, Frank

    2015-09-08

    The recently developed domain-based local pair natural orbital coupled cluster theory with single, double, and perturbative triple excitations (DLPNO-CCSD(T)) delivers results that are closely approaching those of the parent canonical coupled cluster method at a small fraction of the computational cost. A recent extended benchmark study established that, depending on the three main truncation thresholds, it is possible to approach the canonical CCSD(T) results within 1 kJ (default setting, TightPNO), 1 kcal/mol (default setting, NormalPNO), and 2-3 kcal (default setting, LoosePNO). Although thresholds for calculations with TightPNO are 2-4 times slower than those based on NormalPNO thresholds, they are still many orders of magnitude faster than canonical CCSD(T) calculations, even for small and medium sized molecules where there is little locality. The computational effort for the coupled cluster step scales nearly linearly with system size. Since, in many instances, the coupled cluster step in DLPNO-CCSD(T) is cheaper or at least not much more expensive than the preceding Hartree-Fock calculation, it is useful to compare the method against modern density functional theory (DFT), which requires an effort comparable to that of Hartree-Fock theory (at least if Hartree-Fock exchange is part of the functional definition). Double hybrid density functionals (DHDF's) even require a MP2-like step. The purpose of this article is to evaluate the cost vs accuracy ratio of DLPNO-CCSD(T) against modern DFT (including the PBE, B3LYP, M06-2X, B2PLYP, and B2GP-PLYP functionals and, where applicable, their van der Waals corrected counterparts). To eliminate any possible bias in favor of DLPNO-CCSD(T), we have chosen established benchmark sets that were specifically proposed for evaluating DFT functionals. It is demonstrated that DLPNO-CCSD(T) with any of the three default thresholds is more accurate than any of the DFT functionals. Furthermore, using the aug-cc-pVTZ basis set and

  1. Electron-boson spectral density function of correlated multiband systems obtained from optical data: Ba0.6K0.4Fe2As2 and LiFeAs.

    Science.gov (United States)

    Hwang, Jungseek

    2016-03-31

    We introduce an approximate method which can be used to simulate the optical conductivity data of correlated multiband systems for normal and superconducting cases by taking advantage of a reversed process in comparison to a usual optical data analysis, which has been used to extract the electron-boson spectral density function from measured optical spectra of single-band systems, like cuprates. We applied this method to optical conductivity data of two multiband pnictide systems (Ba0.6K0.4Fe2As2 and LiFeAs) and obtained the electron-boson spectral density functions. The obtained electron-boson spectral density consists of a sharp mode and a broad background. The obtained spectral density functions of the multiband systems show similar properties as those of cuprates in several aspects. We expect that our method helps to reveal the nature of strong correlations in the multiband pnictide superconductors.

  2. Ions in mixed dielectric solvents: density profiles and osmotic pressure between charged interfaces.

    Science.gov (United States)

    Ben-Yaakov, Dan; Andelman, David; Harries, Daniel; Podgornik, Rudi

    2009-04-30

    The forces between charged macromolecules, usually given in terms of osmotic pressure, are highly affected by the intervening ionic solution. While in most theoretical studies the solution is treated as a homogeneous structureless dielectric medium, recent experimental studies concluded that, for a bathing solution composed of two solvents (binary mixture), the osmotic pressure between charged macromolecules is affected by the binary solvent composition. By adding local solvent composition terms to the free energy, we obtain a general expression for the osmotic pressure, in planar geometry and within the mean-field framework. The added effect is due to the permeability inhomogeneity and nonelectrostatic short-range interactions between the ions and solvents (preferential solvation). This effect is mostly pronounced at small distances and leads to a reduction in the osmotic pressure for macromolecular separations of the order 1-2 nm. Furthermore, it leads to a depletion of one of the two solvents from the charged macromolecules (modeled as planar interfaces). Lastly, by comparing the theoretical results with experimental ones, an explanation based on preferential solvation is offered for recent experiments on the osmotic pressure of DNA solutions.

  3. Measurement of axial neutral density profiles in a microwave discharge ion thruster by laser absorption spectroscopy with optical fiber probes.

    Science.gov (United States)

    Tsukizaki, Ryudo; Koizumi, Hiroyuki; Nishiyama, Kazutaka; Kuninaka, Hitoshi

    2011-12-01

    In order to reveal the physical processes taking place within the "μ10" microwave discharge ion thruster, internal plasma diagnosis is indispensable. However, the ability of metallic probes to access microwave plasmas biased at a high voltage is limited from the standpoints of the disturbance created in the electric field and electrical isolation. In this study, the axial density profiles of excited neutral xenon were successfully measured under ion beam acceleration by using a novel laser absorption spectroscopy system. The target of the measurement was metastable Xe I 5p(5)((2)P(0) (3/2))6s[3/2](0) (2) which absorbed a wavelength of 823.16 nm. Signals from laser absorption spectroscopy that swept a single-mode optical fiber probe along the line of sight were differentiated and converted into axial number densities of the metastable neutral particles in the plasma source. These measurements revealed a 10(18) m(-3) order of metastable neutral particles situated in the waveguide, which caused two different modes during the operation of the μ10 thruster. This paper reports a novel spectroscopic measurement system with axial resolution for microwave plasma sources utilizing optical fiber probes.

  4. Recombinant MUC1 probe authentically reflects cell-specific O-glycosylation profiles of endogenous breast cancer mucin. High density and prevalent core 2-based glycosylation.

    Science.gov (United States)

    Müller, Stefan; Hanisch, Franz-Georg

    2002-07-19

    Knowledge about the O-linked glycan chains of tumor-associated MUC1 is primarily based on enzymatic and immunochemical evidence. To obtain structural information and to overcome limitations by the scarcity of endogenous mucin, we expressed a recombinant glycosylation probe corresponding to six MUC1 tandem repeats in four breast cancer cell lines. Comparative analyses of the O-glycan profiles were performed after hydrazinolysis and normal phase chromatography of 2-aminobenzamide-labeled glycans. Except for a general reduction in the O-glycan chain lengths and a high density glycosylation, no common structural pattern was revealed. T47D fusion protein exhibits an almost complete shift from core 2 to core 1 expression with a preponderance of sialylated glycans. By contrast, MCF-7, MDA-MB231, and ZR75-1 cells glycosylate the MUC1 repeat peptide preferentially with core 2-based glycans terminating mostly with alpha 3-linked sialic acid (MDA-MB231, ZR75-1) or alpha 2/3-linked fucose (MCF-7). Endogenous MUC1 from T47D and MCF-7 cell supernatants revealed almost identical O-glycosylation profiles compared with the respective recombinant probes, indicating that the fusion proteins reflected the authentic O-glycan profiles of the cells. The structural patterns in the majority of cells under study are in conflict with biosynthetic models of MUC1 O-glycosylation in breast cancer, which claim that the truncation of normal core 2-based polylactosamine structures to short sialylated core 1-based glycans is due to the reduced activity of core 2-forming beta 6-N-acetylglucosaminyltransferases and/or to overexpression of competitive alpha 3- sialyltransferase.

  5. The co-evolution of total density profiles and central dark matter fractions in simulated early-type galaxies

    Science.gov (United States)

    Remus, Rhea-Silvia; Dolag, Klaus; Naab, Thorsten; Burkert, Andreas; Hirschmann, Michaela; Hoffmann, Tadziu L.; Johansson, Peter H.

    2017-01-01

    We present evidence from cosmological hydrodynamical simulations for a co-evolution of the slope of the total (dark and stellar) mass density profile, γtot, and the dark matter fraction within the half-mass radius, fDM, in early-type galaxies. The relation can be described as γtot = A fDM + B for all systems at all redshifts. The trend is set by the decreasing importance of gas dissipation towards lower redshifts and for more massive systems. Early-type galaxies are smaller, more concentrated, have lower fDM and steeper γtot at high redshifts and at lower masses for a given redshift; fDM and γtot are good indicators for growth by `dry' merging. The values for A and B change distinctively for different feedback models, and this relation can be used as a test for such models. A similar correlation exists between γtot and the stellar mass surface density Σ*. A model with weak stellar feedback and feedback from black holes is in best agreement with observations. All simulations, independent of the assumed feedback model, predict steeper γtot and lower fDM at higher redshifts. While the latter is in agreement with the observed trends, the former is in conflict with lensing observations, which indicate constant or decreasing γtot. This discrepancy is shown to be artificial: the observed trends can be reproduced from the simulations using observational methodology to calculate the total density slopes.

  6. Improving the AGR Fuel Testing Power Density Profile Versus Irradiation-Time in the Advanced Test Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Gray S. Chang; David A. Petti; John T. Maki; Misti A. Lillo

    2009-05-01

    The Very High Temperature gas-cooled Reactor (VHTR), which is currently being developed, achieves simplification of safety through reliance on ceramic-coated fuel particles. Each TRISO-coated fuel particle has its own containment which serves as the principal barrier against radionuclide release under normal operating and accident conditions. These fuel particles, in the form of graphite fuel compacts, are currently undergoing a series of irradiation tests in the Advanced Test Reactor (ATR) at the Idaho National Laboratory (INL) to support the Advanced Gas-Cooled Reactor (AGR) fuel qualification program. A representive coated fuel particle with an 235U enrichment of 19.8 wt% was used in this analysis. The fuel burnup analysis tool used to perform the neutronics study reported herein, couples the Monte Carlo transport code MCNP, with the radioactive decay and burnup code ORIGEN2. The fuel burnup methodology known as Monte-Carlo with ORIGEN2 (MCWO) was used to evaluate the AGR experiment assembly and demonstrate compliance with ATR safety requirements. For the AGR graphite fuel compacts, the MCWO-calculated fission power density (FPD) due to neutron fission in 235U is an important design parameter. One of the more important AGR fuel testing requirements is to maintain the peak fuel compact temperature close to 1250°C throughout the proposed irradiation campaign of 550 effective full power days (EFPDs). Based on the MCWO-calculated FPD, a fixed gas gap size was designed to allow regulation of the fuel compact temperatures throughout the entire fuel irradiation campaign by filling the gap with a mixture of helium and neon gases. The chosen fixed gas gap can only regulate the peak fuel compact temperature in the desired range during the irradiation test if the ratio of the peak power density to the time-dependent low power density (P/T) at 550 EFPDs is less than 2.5. However, given the near constant neutron flux within the ATR driver core and the depletion of 235U in

  7. Antimicrobial resistance profile of Staphylococcus aureus isolates obtained from skin and soft tissue infections of outpatients from a university hospital in Recife - PE, Brazil*

    Science.gov (United States)

    Caraciolo, Fabiana Beserra; Maciel, Maria Amélia Vieira; dos Santos, Josemir Belo; Rabelo, Marcelle Aquino; Magalhães, Vera

    2012-01-01

    BACKGROUND Staphylococcus aureus has a notable ability to acquire resistance to antibiotics, and methicillin resistance represents a growing public health problem. Methicillin-resistant S. aureus (MRSA) has also become important outside the hospital environment, particularly in the United States. In Brazil, since 2005, cases of community skin infections caused by MRSA have been reported, but resistance studies involving outpatients are scarce. OBJECTIVE To know the resistance profile of S. aureus involved in skin and soft tissue infections of patients seen at the Dermatology outpatient clinic of a university hospital in Recife, Pernambuco State, northeastern Brazil. METHODS Prospective study involving 30 patients with skin and soft tissue infections, seen at the Dermatology outpatient clinic from May until November 2011. To evaluate the susceptibility of S. aureus to antibiotics, the disk diffusion method and oxacillin screening agar were used. RESULTS From a total of 30 samples of skin lesions, 19 (63%) had positive culture for S. aureus. The following resistance patterns of S. aureus were observed: penicillin, 95%; tetracycline, 32%; erythromycin, 21%; gentamicin, 16%; cefoxitin, 11%; oxacillin, 11%; trimethoprim-sulfamethoxazole, 11%; chloramphenicol, 11%; clindamycin, 5% ; and ciprofloxacin, 0%. One of the identified MRSA was obtained from a patient without risk factors for its acquisition, and was resistant, beyond to the beta-lactams, only to tetracycline. CONCLUSIONS With regard to the resistance patterns of S. aureus, resistances to tetracycline, erythromycin and gentamicin were the highest. It was documented, for the first time in Pernambuco, a case of skin infection caused by community-associated MRSA. PMID:23197204

  8. Emission considering self-absorption of OH to simultaneously obtain the OH density and gas temperature: validation, non-equilibrium effects and limitations

    Science.gov (United States)

    Du, Yanjun; Nayak, Gaurav; Oinuma, Gaku; Ding, Yanjun; Peng, Zhimin; Bruggeman, Peter J.

    2017-09-01

    The measurement of absolute densities of ubiquitous OH radicals and gas temperatures in water containing plasmas has recently drawn a lot of attention. In this paper, we extend the self-absorption model introduced in Du et al 2016 Plasma Sources Sci. Technol. 25 04LT02 with a description of the excited state by a superposition of two Boltzmann distributions to take the non-thermal rotational distribution of the excited state into account. This technique is applied to a diffuse He + H2O RF discharge and it is shown that in addition to the determination of the ground state OH density and rotational temperature, the properties of the excited state OH(A) can also be simultaneously determined. A model of the steady-state distribution of the hot and cold group density of OH(A) is able to describe the dependence of the rotational population distributions of the excited state as a function of the water concentration. The method is also applied to a filamentary Ar + H2O DBD. While the non-homogeneous nature of the DBD leads to complications, the production of OH(A) by multiple production mechanisms leading to a complex nascent rotational population distribution causes the fitting procedure of the emission spectrum (with self-absorption) to break down.

  9. Inferring Average Ground Profiles of the Muon Density of Inclined Air Showers from Monte-Carlo Simulations at Ultra-High Energy

    CERN Document Server

    Dembinski, Hans; Deligny, Olivier; Hebbeker, Thomas

    2009-01-01

    A standard method to measure ultra-high energy cosmic rays is the sampling of the ground particle profile of the extensive air shower that is produced in the atmosphere with an array of surface detectors. The primary energy of inclined air showers with zenith angles >60 Deg can be reconstructed by using simulated 2-D profiles of the ground density of muons. We will present an effective way to extract such profiles from a library of Monte-Carlo simulated air showers. Also, we will demonstrate a way to speed up the simulation of ground profiles of the muon density in very inclined showers by three orders of magnitude, if only the muon component in the shower is of interest.

  10. Initial measurements of plasma current and electron density profiles using a polarimeter/interferometer (POINT) for long pulse operation in EAST (invited)

    Science.gov (United States)

    Liu, H. Q.; Qian, J. P.; Jie, Y. X.; Ding, W. X.; Brower, D. L.; Zou, Z. Y.; Li, W. M.; Lian, H.; Wang, S. X.; Yang, Y.; Zeng, L.; Lan, T.; Yao, Y.; Hu, L. Q.; Zhang, X. D.; Wan, B. N.

    2016-11-01

    A double-pass, radially viewing, far-infrared laser-based POlarimeter-INTerferometer (POINT) system utilizing the three-wave technique has been implemented for diagnosing the plasma current and electron density profiles in the Experimental Advanced Superconducting Tokamak (EAST). POINT has been operated routinely during the most recent experimental campaign and provides continuous 11 chord line-integrated Faraday effect and density measurement throughout the entire plasma discharge for all heating schemes and all plasma conditions (including ITER relevant scenario development). Reliability of both the polarimetric and interferometric measurements is demonstrated in 25 s plasmas with H-mode and 102 s long-pulse discharges. Current density, safety factor (q), and electron density profiles are reconstructed using equilibrium fitting code (EFIT) with POINT constraints for the plasma core.

  11. Ozone profiles obtained by DIAL technique at Maïdo Observatory in La Reunion Island: comparisons with ECC ozone-sondes, ground-based FTIR spectrometer and microwave radiometer measurements

    Directory of Open Access Journals (Sweden)

    Portafaix T.

    2016-01-01

    Full Text Available A DIAL lidar system performing stratospheric ozone profile measurements from 15 to 45 km is installed at Reunion Island (southwest of Indian Ocean. The purpose of this communication is to present this DIAL system mounted now at the new Maïdo Observatory since February 2013, and the ozone profile retrieval. The first stratospheric ozone profiles obtained during 2013 and 2014 will be presented and discussed. Inter-comparison and differences observed with other high vertical resolution ozone profiles performed by ECC ozonesonde will be shown. Finally, comparisons with low vertical resolution ozone profiles retrieved from microwave and FTIR remote sensing measurements performed at Maïdo will be carried out, making appropriate use of the associated averaging kernels

  12. Ozone profiles obtained by DIAL technique at Maïdo Observatory in La Reunion Island: comparisons with ECC ozone-sondes, ground-based FTIR spectrometer and microwave radiometer measurements

    Science.gov (United States)

    Portafaix, T.; Godin-Beekmann, S.; Payen, G.; de Mazière, M.; Langerock, B.; Fernandez, S.; Posny, F.; Cammas, J. P.; Metzger, J. M.; Bencherif, H.; Vigouroux, C.; Marquestaut, N.

    2016-06-01

    A DIAL lidar system performing stratospheric ozone profile measurements from 15 to 45 km is installed at Reunion Island (southwest of Indian Ocean). The purpose of this communication is to present this DIAL system mounted now at the new Maïdo Observatory since February 2013, and the ozone profile retrieval. The first stratospheric ozone profiles obtained during 2013 and 2014 will be presented and discussed. Inter-comparison and differences observed with other high vertical resolution ozone profiles performed by ECC ozonesonde will be shown. Finally, comparisons with low vertical resolution ozone profiles retrieved from microwave and FTIR remote sensing measurements performed at Maïdo will be carried out, making appropriate use of the associated averaging kernels

  13. Hydrolysis Profiles of Formalin Fixed Paraffin-Embedded Tumors Based on IOD (Integrated Optical Density and Nuclear Texture Feature Measurements

    Directory of Open Access Journals (Sweden)

    Margareta Fležar

    1999-01-01

    Full Text Available The aim of the study was to determine optimal hydrolysis time for the Feulgen DNA staining of archival formalin fixed paraffin‐embedded surgical samples, prepared as single cell suspensions for image cytometric measurements. The nuclear texture features along with the IOD (integrated optical density of the tumor nuclei were analysed by an automated high resolution image cytometer as a function of duration of hydrolysis treatment (in 5 N HCl at room temperature. Tissue blocks of breast carcinoma, ovarian serous carcinoma, ovarian serous tumor of borderline malignancy and leiomyosarcoma were included in the study. IOD hydrolysis profiles showed plateau between 30 and 60 min in the breast carcinoma and leiomyosarcoma, and between 40 and 60 min in the ovarian serous carcinoma and ovarian serous tumor of borderline malignancy. Most of the nuclear texture features remained stable after 20 min of hydrolysis treatment. Our results indicate that the optimal hydrolysis time for IOD and for nuclear texture feature measurements, was between 40 and 60 min in the cell preparations from tissue blocks of three epithelial and one soft tissue tumor.

  14. Quantification of mid and late evoked sinks in laminar current source density profiles of columns in the primary auditory cortex.

    Science.gov (United States)

    Schaefer, Markus K; Hechavarría, Julio C; Kössl, Manfred

    2015-01-01

    Current source density (CSD) analysis assesses spatiotemporal synaptic activations at somatic and/or dendritic levels in the form of depolarizing current sinks. Whereas many studies have focused on the short (primary auditory cortex of Mongolian gerbils. By applying an algorithm for contour calculation, three distinct mid and four late evoked sinks were identified in layers I, III, Va, VIa, and VIb. Our results further showed that the patterns of intracortical information-flow remained qualitatively similar for low and for high sound pressure level stimuli at the characteristic frequency (CF) as well as for stimuli ± 1 octave from CF. There were, however, differences associated with the strength, vertical extent, onset latency, and duration of the sinks for the four stimulation paradigms used. Stimuli one octave above the most sensitive frequency evoked a new, and quite reliable, sink in layer Va whereas low level stimulation led to the disappearance of the layer VIb sink. These data indicate the presence of input sources specifically activated in response to level and/or frequency parameters. Furthermore, spectral integration above vs. below the CF of neurons is asymmetric as illustrated by CSD profiles. These results are important because synaptic feedback associated with mid and late sinks-beginning at 50 ms post stimulus latency-is likely crucial for response modulation resulting from higher order processes like memory, learning or cognitive control.

  15. Water temperature, salinity, and density profiles collected by CTD from multiple cruises in the Northeast Pacific Ocean, the Bering Sea, and the Gulf of Alaska from 2001-01 to 2001-10 (NCEI Accession 0001112)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profile and density profiles were collected using CTD from NOAA Ship MILLER FREEMAN, NOAA Ship RONALD H. BROWN, and SIR WILFRED LAURIER in the Northeast...

  16. Morphology and gas sensing characteristics of density-controlled CuO nanostructures obtained by varying the oxygen partial pressure during growth

    Science.gov (United States)

    Lee, Dongjin; Jin, Changhyun; Noh, Youngwook; Park, Seokhyun; Choi, Sun-Woo

    2016-07-01

    By exerting different O2 partial pressures (0, 20, 40, and 60 sccm) onto copper substrates, we discovered that the growth parameter, namely, the O2 flow rate, affects the degree of nucleation, diameter, length, and crystalline quality of CuO nanowires (NWs). Scanning electron microscopy (SEM), X-ray diffraction (XRD), and transmission electron microscopy (TEM) were used to analyze the evolution of the morphological and the microstructural changes in the CuO nanostructures. The formation of a Cu2O interlayer between the Cu and the CuO layers could be adjusted by controlling more precisely the O2 flow rate. In addition, the reducing (H2S) and the oxidizing (O2, NO2, and SO2) gas sensing performances of these O2-assisted CuO NWs were compared with those of CuO NWs grown in static air. The response to the reducing H2S of the sensors based on CuO NWs grown using O2 at 40 sccm showed a higher electrical change and faster response and recovery times than the sensors based on CuO NWs grown using lower O2 flow rates, including the ones grown in static air and/or used for sensing oxidizing gases (O2, NO2, and SO2) did. On the basis of their growth and their gas-sensing applications, the possible mechanisms characteristic of the density-controlled CuO NWs grown using various O2 partial pressures are discussed.

  17. Performance potential of low-defect density silicon thin-film solar cells obtained by electron beam evaporation and laser crystallisation

    Directory of Open Access Journals (Sweden)

    Kim K. H.

    2013-01-01

    Full Text Available A few microns thick silicon films on glass coated with a dielectric intermediate layer can be crystallised by a single pass of a line-focused diode laser beam. Under favorable process conditions relatively large linear grains with low defect density are formed. Most grain boundaries are defect-free low-energy twin-boundaries. Boron-doped laser crystallised films are processed into solar cells by diffusing an emitter from a phosphorous spin-on-dopant source, measuring up to 539 mV open-circuit voltage prior to metallisation. After applying a point-contact metallisation the best cell achieves 7.8% energy conversion efficiency, open-circuit voltage of 526 mV and short-circuit current of 26 mA/cm2. The efficiency is significantly limited by a low fill-factor of 56% due to the simplified metallisation approach. The internal quantum efficiency of laser crystallised cells is consistent with low front surface recombination. By improving cell metallisation and enhancing light-trapping the efficiencies of above 13% can be achieved.

  18. Superior critical current density obtained in MgB2 bulks via employing carbon-coated boron and minor Cu addition

    Science.gov (United States)

    Peng, Junming; Liu, Yongchang; Ma, Zongqing; Shahriar Al Hossain, M.; Xin, Ying; Jin, Jianxun

    2016-09-01

    High performance Cu doped MgB2 bulks were prepared by an in-situ method with carbon-coated amorphous boron as precursor. It was found that the usage of carbon-coated boron in present work leads to the formation of uniformly refined MgB2 grains, as well as a high level of homogeneous carbon doping in the MgB2 samples, which significantly enhance the Jc in both Cu doped and undoped bulks compared to MgB2 bulks with normal amorphous boron precursor. Moreover, minor Cu can service as activator, and thus facilitates the growth of MgB2 grains and improves crystallinity and grain connectivity, which can bring about the excellent critical current density (Jc) at self fields and low fields (the best values are 7 × 105 A/cm2 at self fields, and 1 × 105 A/cm2 at 2 T, 20 K, respectively). Simultaneously, minor Cu addition can reduce the amount of MgO impurity significantly, also contributing to the improvement of Jc at low fields. Our work suggests that Cu-activated sintering combined with employment of carbon-coated amorphous boron as precursor could be a promising technique to produce practical MgB2 bulks or wires with excellent Jc on an industrial scale.

  19. Free reaction enthalpy profile of the Schrock cycle derived from density functional theory calculations on the full [Mo(HIPT)N3N] catalyst.

    Science.gov (United States)

    Thimm, Wulf; Gradert, Christian; Broda, Henning; Wennmohs, Frank; Neese, Frank; Tuczek, Felix

    2015-10-05

    A series of density functional theory (DFT) calculations on the full [Mo(HIPT)N3N] catalyst are performed to obtain an energy profile of the Schrock cycle. This is a continuation of our earlier investigation of this cycle in which the bulky hexaisopropyterphenyl (HIPT) substituents of the ligand were replaced by hydrogen atoms (Angew. Chem., Int. Ed. 2005, 44, 5639). In an effort to provide a treatment that is as converged as possible from a quantum-chemical point of view, the present study now fully takes the HIPT moieties into account. Moreover, structures and energies are calculated with a near-saturated basis set, leading to models with 280 atoms and 4850 basis functions. Solvent and scalar relativistic effects have been treated using the conductor-like screening model and zeroth-order regular approximation, respectively. Free reaction enthalpies are evaluated using the PBE and B3LYP functionals. A comparison to the available experimental data reveals much better agreement with the experiment than preceding DFT treatments of the Schrock cycle. In particular, free reaction enthalpies of reduction steps and NH3/N2 exchange are now excellently reproduced.

  20. Sap flow measurements combining sap-flux density radial profiles with punctual sap-flux density measurements in oak trees (Quercus ilex and Quercus pyrenaica) - water-use implications in a water-limited savanna-

    Science.gov (United States)

    Reyes, J. Leonardo; Lubczynski1, Maciek W.

    2010-05-01

    measurements using the HFD-measured radial profiles. The standard TDP daily mean of sap-flux density was 95% higher than the 2cm equivalent of the HFD for Q. ilex and 70% higher for Q. pyrenaica. NTG-corrected TDP daily mean of sap-flux density was 34% higher than HFD for Q. ilex and 47% lower for Q. pyrenaica. Regarding sap flow measurements, the standard TDP sap flow was 81% higher than HFD sap flow for Q. ilex and 297% for Q. pyrenaica. The NTG-corrected TDP sap flow was 24% higher than HFD sap flow for Q. ilex and 23% for Q. pyrenaica. The radial correction, for TDP-NTG-corrected sap-flux density, produced sap-flow measurements in well agreement with HFD, just slightly lower (-3% Q.i. and -4% Q.p.). The TDP-HFD sap flow data acquired in dry season over the savanna type of sparsely distributed oak trees (Q. ilex & Q. pyrenaica) showed that the TDP method must be corrected for NTG and for radial variability of sap flux density in trees with sapwood thicker than 2 cm. If such corrections are not taken into consideration, the amount of accounted water used by the trees is prone to overestimation, especially for Quercus pyrenaica. The obtained results indicate also that the combination of HFD and TDP leads to an efficient and accurate operational sap flow measurement schema that is currently in the optimization stage.

  1. Dislocation density and Burgers vector population in fiber-textured Ni thin films determined by high-resolution X-ray line profile analysis

    DEFF Research Database (Denmark)

    Csiszár, Gábor; Pantleon, Karen; Alimadadi, Hossein

    2012-01-01

    Nanocrystalline Ni thin films have been produced by direct current electrodeposition with different additives and current density in order to obtain 〈100〉, 〈111〉 and 〈211〉 major fiber textures. The dislocation density, the Burgers vector population and the coherently scattering domain size distri...

  2. Measurement of deuterium density profiles in the H-mode steep gradient region using charge exchange recombination spectroscopy on DIII-D

    Science.gov (United States)

    Haskey, S. R.; Grierson, B. A.; Burrell, K. H.; Chrystal, C.; Groebner, R. J.; Kaplan, D. H.; Pablant, N. A.; Stagner, L.

    2016-11-01

    Recent completion of a thirty two channel main-ion (deuterium) charge exchange recombination spectroscopy (CER) diagnostic on the DIII-D tokamak [J. L. Luxon, Nucl. Fusion 42, 614 (2002)] enables detailed comparisons between impurity and main-ion temperature, density, and toroidal rotation. In a H-mode DIII-D discharge, these new measurement capabilities are used to provide the deuterium density profile, demonstrate the importance of profile alignment between Thomson scattering and CER diagnostics, and aid in determining the electron temperature at the separatrix. Sixteen sightlines cover the core of the plasma and another sixteen are densely packed towards the plasma edge, providing high resolution measurements across the pedestal and steep gradient region in H-mode plasmas. Extracting useful physical quantities such as deuterium density is challenging due to multiple photoemission processes. These challenges are overcome using a detailed fitting model and by forward modeling the photoemission using the FIDASIM code, which implements a comprehensive collisional radiative model.

  3. High-Resolution Sedimentation Rates at IODP Sites U1424 and U1427 since the late Pliocene from spectral-analyzing GRA Bulk Density and RGB Color Profiles

    Science.gov (United States)

    Gorgas, Thomas; Irino, Tomohisa; Tada, Ryuji

    2016-04-01

    increase in detrital fraction. By contrast moderate to higher SRs were associated with lower GRA density and due to a higher diatom flux. At Site U1427 a noticeable wax-and wane pattern in SRs corresponds to a predominance of precessional cycles in evolutive spectra. Such cyclicity has been also identified in records from other world regions (i.e. Australia; equatorial Africa, off India) and related to orbital solar cycles and wind patterns associated with the Monsoon. At the deep-water Site U1424 we model SR patterns which roughly correspond with those observed off SW Africa (southern part of the Benguela Current System) for the past 2.5 Myr. This possibly provides evidence for a teleconnection between the Southern and Northern hemispheres, where variabilities in the Northern polar front and ice sheet flows caused corresponding climatic and tectonic changes throughout the Pleistocene. By contrast, SR profiles calculated for the shallow-water Site U1427 represent perhaps more local and regional climate, sea level and bioproductivity variabilities than those modeled for the deep-water Site U1424. Thus, the variable dominance and coexistence of the various Milankovitch cycles in our records obtained at IODP Sites U1424 and U1427 might therefore reflect the complex interplay and control of the high-latitude (i.e., obliquity) with the low-latitude (i.e., precessional) of the orbital forcing spectrum.

  4. Application of Thomson scattering at 1.06{mu}m as a diagnostic for spatial profile measurements of electron temperature and density on the TCV tokamak

    Energy Technology Data Exchange (ETDEWEB)

    Franke, S. [Ecole Polytechnique Federale, Lausanne (Switzerland). Centre de Recherche en Physique des Plasma (CRPP)

    1997-04-01

    The variable configuration tokamak, TCV, in operation at CRPP since the end of 1991, is a particularly challenging machine with regard to the experimental system that must provide essential information regarding properties of confined plasmas with strongly shaped, non-circular cross-sections. The importance of the energy confinement issue in a machine designed specifically for the investigation of the effect of plasma shape on confinement and stability is self-evident, as is the necessity for a diagnostic capable of providing the profiles of electron temperature and density required for evaluation of this confinement. For TCV, a comprehensive Thomson Scattering (TS) diagnostic was the natural choice, specifically owing to the resulting spatially localized and time resolved measurement. The details of the system installed on TCV, together with the results obtained from the diagnostic comprise the subject matter of this thesis. A first version of the diagnostic was equipped with only ten observation volumes. In this case, adequate spatial resolution can only be maintained if measurements are limited to plasmas located in the upper half of the highly elongated TCV vacuum vessel. The system has recently been upgraded through the addition of a further fifteen observation volumes, together with major technical improvements in the scattered light detection system. This new version now permits TS observations in all TCV plasma configurations, including equilibria produced in the lower and upper halves of the vacuum vessel and the highly elongated plasmas now routinely created. Whilst a description of the new detection system along with some results obtained using the extended set of observation volumes are included, this thesis reports principally on the hardware details of and the interpretation of data from the original, ten observation volume system. (author) figs., tabs., 75 refs.

  5. Application of Thomson scattering at 1.06{mu}m as a diagnostic for spatial profile measurements of electron temperature and density on the TCV tokamak

    Energy Technology Data Exchange (ETDEWEB)

    Franke, S. [Ecole Polytechnique Federale, Lausanne (Switzerland). Centre de Recherche en Physique des Plasma (CRPP)

    1997-04-01

    The variable configuration tokamak, TCV, in operation at CRPP since the end of 1991, is a particularly challenging machine with regard to the experimental system that must provide essential information regarding properties of confined plasmas with strongly shaped, non-circular cross-sections. The importance of the energy confinement issue in a machine designed specifically for the investigation of the effect of plasma shape on confinement and stability is self-evident, as is the necessity for a diagnostic capable of providing the profiles of electron temperature and density required for evaluation of this confinement. For TCV, a comprehensive Thomson Scattering (TS) diagnostic was the natural choice, specifically owing to the resulting spatially localized and time resolved measurement. The details of the system installed on TCV, together with the results obtained from the diagnostic comprise the subject matter of this thesis. A first version of the diagnostic was equipped with only ten observation volumes. In this case, adequate spatial resolution can only be maintained if measurements are limited to plasmas located in the upper half of the highly elongated TCV vacuum vessel. The system has recently been upgraded through the addition of a further fifteen observation volumes, together with major technical improvements in the scattered light detection system. This new version now permits TS observations in all TCV plasma configurations, including equilibria produced in the lower and upper halves of the vacuum vessel and the highly elongated plasmas now routinely created. Whilst a description of the new detection system along with some results obtained using the extended set of observation volumes are included, this thesis reports principally on the hardware details of and the interpretation of data from the original, ten observation volume system. (author) figs., tabs., 75 refs.

  6. From slant column densities to trace gas profiles: Post processing data from the new MAX-DOAS network in Mexico City

    Science.gov (United States)

    Friedrich, M. M.; Stremme, W.; Rivera, C. I.; Arellano, E. J.; Grutter, M.

    2014-12-01

    The new MAX-DOAS network in Mexico City provides results of O4, HCHO and NO2 slant column densities (SCD). Here, we present a new numerical code developed to retrieve gas profiles of NO2 and HCHO using radiative transfer simulations. We present first results of such profiles from the MAX-DOAS station located at UNAM campus. The code works in two steps: First, the O4 slant column density information is used to retrieve an aerosol profile. As an a-priori aerosol profile, we use averaged ceilometer data measured at UNAM and scaled to the total optical depth provided by the Aeronet data base. In the second step, the retrieved aerosol profile information is used together with the trace gas (HCHO or NO2) SCDs to retrieve the trace gas profiles. The inversion is based on a gauss-newton iteration scheme and uses constrained least square fitting with either optimal estimation or Tihkonov regularization. For the latter, the regulation matrix is currently constructed from the discrete first derivative operator. The forward model uses the radiative transfer code VLIDORT. The inputs to VLIDORT are calculated using temperature and pressure information from daily radiosounde measurements and aerosol single scattering optical depths and asymmetry factors from the Aeronet data base for Mexico City. For the gas absorption cross sections we use the same values as were used for the SCD calculation from the recorded spectra using QDOAS. Besides demonstrating the functionality of the algorithm showing profile retrievals of simulated SCDs with added random noise, we present HCHO and NO2 profiles retrieved from SCDs calculated from the MAX-DOAS measurements at UNAM campus at selected days.

  7. Characterization of Electron Temperature and Density Profiles of Plasmas Produced by Nike KrF Laser for Laser Plasma Instability (LPI) Research

    Science.gov (United States)

    Oh, Jaechul; Weaver, J. L.; Phillips, L.; Obenschain, S. P.; Schmitt, A. J.; Kehne, D. M.; Chan, L.-Y.; Serlin, V.

    2011-10-01

    Previous experiments with Nike KrF laser (λ = 248 nm , Δν ~ 1 THz) observed LPI signatures near quarter critical density (nc / 4) in CH plasmas, however, detailed measurement of the temperature (Te) and density (ne) profiles was missing. The current Nike LPI campaign will perform experimental determination of the plasma profiles. A side-on grid imaging refractometer (GIR) is the main diagnostic to resolve Te and ne in space taking 2D snapshots of probe laser (λ = 266 nm , Δt = 8 psec) beamlets (50 μm spacing) refracted by the plasma at laser peak time. Ray tracing of the beamlets through hydrodynamically simulated (FASTRAD3D) plasma profiles estimates the refractometer may access densities up to ~ 0 . 2nc . With the measured Te and ne profiles in the plasma corona, we will discuss analysis of light data radiated from the plasmas in spectral ranges relevant to two plasmon decay and convective Raman instabilities. Validity of the (Te ,ne) data will also be discussed for the thermal transport study. Work supported by DoE/NNSA and ONR and performed at NRL.

  8. 3D stellar kinematics at the Galactic center: measuring the nuclear star cluster spatial density profile, black hole mass, and distance

    CERN Document Server

    Do, T; Yelda, S; Ghez, A M; Bullock, J; Kaplinghat, M; Lu, J R; Peter, A G H; Phifer, K

    2013-01-01

    We present 3D kinematic observations of stars within the central 0.5 pc of the Milky Way nuclear star cluster using adaptive optics imaging and spectroscopy from the Keck telescopes. Recent observations have shown that the cluster has a shallower surface density profile than expected for a dynamically relaxed cusp, leading to important implications for its formation and evolution. However, the true three dimensional profile of the cluster is unknown due to the difficulty in de-projecting the stellar number counts. Here, we use spherical Jeans modeling of individual proper motions and radial velocities to constrain for the first time, the de-projected spatial density profile, cluster velocity anisotropy, black hole mass ($M_\\mathrm{BH}$), and distance to the Galactic center ($R_0$) simultaneously. We find that the inner stellar density profile of the late-type stars, $\\rho(r)\\propto r^{-\\gamma}$ to have a power law slope $\\gamma=0.05_{-0.60}^{+0.29}$, much more shallow than the frequently assumed Bahcall $\\&am...

  9. Biases of CO2 Storage in Eddy Flux Measurements pertinent to Vertical Configurations of a Profile System and CO2 Density Averaging

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Bai [ORNL; Hanson, Paul J [ORNL; Riggs, Jeffery S [ORNL; Pallardy, Stephen G. [University of Missouri; Hosman, K. P. [University of Missouri; Meyers, T. P. [NOAA ATDD; Wullschleger, Stan D [ORNL; Gu, Lianhong [ORNL; Heuer, Mark [ATDD, NOAA

    2007-01-01

    CO2 storage in a 30-minute period in a tall forest canopy often makes significant contributions to net ecosystem exchange (NEE) in the early morning and at night. When CO2 storage is properly measured and taken into account, underestimations of NEE on calm nights can be greatly reduced. Using CO2 data from a 12-level profile, we demonstrate that the lower canopy layer (below the thermal inversion) is a disproportional contributor to the total CO2 storage. This is because time derivative of CO2 density ( c/ t) generally shows increasing magnitude of mean and standard deviation with decreasing heights at night and from sunrise to 1000 hr in both growing and dormant seasons. Effects of resolution and configuration in a profiling system on the accuracy of CO2 storage estimation are evaluated by comparing subset profiles to the 12-level benchmark profile. It is demonstrated that the effectiveness of a profiling system in estimating CO2 storage is not only determined by its number of sampling levels but, more importantly, by its vertical configuration. To optimize a profile, one needs to balance the influence of two factors, c/ t and layer thickness, among all vertical sections within a forest. As a key contributor to the total CO2 storage, the lower canopy (with relatively large means and standard deviations of c/ t) requires a higher resolution in a profile system than the layers above. However, if the upper canopy is over-sparsely sampled relative to the lower canopy, the performance of a profile system might be degraded since, in such a situation, the influence of layer thickness dominates over that of c/ t. We also find that, because of different level of complexity in canopy structure, more sampling levels are necessary at our site in order to achieve the same level of accuracy as at a boreal aspen site. These results suggest that, in order to achieve an adequate accuracy in CO2 storage measurements, the number of sampling levels in a profile and its design should

  10. Programs to obtain vertical heights from mean sea level and for computing volume of sand/mineral along beaches: A case study with Kalbadevi beach profiling data and results

    Digital Repository Service at National Institute of Oceanography (India)

    Ganesan, P.

    Two programs have been developed to process profile data, for obtaining vertical heights with respect to mean sea level (M.S.L.) and for computation of volume of heavy mineral / sand accumulation or erosion along the beaches. The final output...

  11. Inorganic profile of some Brazilian medicinal plants obtained from ethanolic extract and ''in natura'' samples

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, M.O.M.; de Sousa, P.T.; Salvador, V.L.R.; Sato, I.M.

    2004-10-03

    The Anadenathera macrocarpa, Schinus molle, Hymenaea courbaril, Cariniana legalis, Solidago microglossa and Stryphnodendron barbatiman, were collected ''in natura'' samples (leaves, flowers, barks and seeds) from different commercial suppliers. The pharmaco-active compounds in ethanolic extracts had been made by the Mato Grosso Federal University (UFMT). The energy-dispersive x-ray fluorescence (ED-XRF) spectrometry was used for the elemental analysis in different parts of the plants and respective ethanolic extracts. The Ca, Cl, Cu, Fe, K, Mg, Mn, Na, Ni, P, Rb, S, Sr and Zn concentrations were determined by the fundamental parameters method. Some specimens showed a similar inorganic profile for ''in natura'' and ethanolic extract samples and some ones showed a distinct inorganic profile. For example, the Anadenathera macrocarpa showed a similar concentration in Mg, P, Cu, Zn and Rb elements in ''in natura'' and ethanolic extract samples; however very different concentration in Na, S, Cl, K , Ca, Mn, Fe and Sr was observed in distinctive samples. The Solidago microglossa showed the K, Ca, Cl, S, Mg, P and Fe elements as major constituents in both samples, suggesting that the extraction process did not affect in a considerable way the ''in natura'' inorganic composition. The elemental composition of the different parts of the plants (leaves, flowers, barks and seeds) has been also determined. For example, the Schinus molle specimen showed P, K, Cl and Ca elements as major constituents in the seeds, Mg, K and Sr in the barks and Mg, S, Cl and Mn in the leaves, demonstrating a differentiated elementary distribution. These inorganic profiles will contribute to evaluate the quality control of the Brazilian herbaceous trade and also will assist to identify which parts of the medicinal plants has greater therapeutic effect.

  12. Routine use of microarray-based gene expression profiling to identify patients with low cytogenetic risk acute myeloid leukemia: accurate results can be obtained even with suboptimal samples.

    Science.gov (United States)

    de la Blétière, Diane Raingeard; Blanchet, Odile; Cornillet-Lefèbvre, Pascale; Coutolleau, Anne; Baranger, Laurence; Geneviève, Franck; Luquet, Isabelle; Hunault-Berger, Mathilde; Beucher, Annaelle; Schmidt-Tanguy, Aline; Zandecki, Marc; Delneste, Yves; Ifrah, Norbert; Guardiola, Philippe

    2012-01-30

    Gene expression profiling has shown its ability to identify with high accuracy low cytogenetic risk acute myeloid leukemia such as acute promyelocytic leukemia and leukemias with t(8;21) or inv(16). The aim of this gene expression profiling study was to evaluate to what extent suboptimal samples with low leukemic blast load (range, 2-59%) and/or poor quality control criteria could also be correctly identified. Specific signatures were first defined so that all 71 acute promyelocytic leukemia, leukemia with t(8;21) or inv(16)-AML as well as cytogenetically normal acute myeloid leukemia samples with at least 60% blasts and good quality control criteria were correctly classified (training set). The classifiers were then evaluated for their ability to assign to the expected class 111 samples considered as suboptimal because of a low leukemic blast load (n = 101) and/or poor quality control criteria (n = 10) (test set). With 10-marker classifiers, all training set samples as well as 97 of the 101 test samples with a low blast load, and all 10 samples with poor quality control criteria were correctly classified. Regarding test set samples, the overall error rate of the class prediction was below 4 percent, even though the leukemic blast load was as low as 2%. Sensitivity, specificity, negative and positive predictive values of the class assignments ranged from 91% to 100%. Of note, for acute promyelocytic leukemia and leukemias with t(8;21) or inv(16), the confidence level of the class assignment was influenced by the leukemic blast load. Gene expression profiling and a supervised method requiring 10-marker classifiers enable the identification of favorable cytogenetic risk acute myeloid leukemia even when samples contain low leukemic blast loads or display poor quality control criterion.

  13. A gravity study along a profile across the Sichuan Basin, the Qinling Mountains and the Ordos Basin (central China): Density, isostasy and dynamics

    Science.gov (United States)

    Zhang, Yongqian; Teng, Jiwen; Wang, Qianshen; Lü, Qingtian; Si, Xiang; Xu, Tao; Badal, José; Yan, Jiayong; Hao, Zhaobing

    2017-10-01

    In order to investigate the structure of the crust beneath the Middle Qinling Mountains (MQL) and neighboring areas in the North China Block and South China Block, a north-south gravity profile from Yuquan in the Sichuan Basin to Yulin in the Ordos Basin was conducted in 2011. The Bouguer gravity anomaly is determined from a high-quality gravity dataset collected between 31°N and 36°N of latitude, and varies between -200 and -110 mGal in the study region. Using accredited velocity density relationships, an initial crust-mantle density model is constructed for MQL and adjacent areas, which is later refined interactively to simulate the observed gravity anomaly. The present study reveals the features of the density and Bouguer gravity with respect to the tectonic units sampled by the profile. The lithosphere density model shows typical density values that depict a layered structure and allow differentiate the blocks that extend along the reference profile. The gravity field calculated by forward modeling from the final density distribution model correlates well with the measured gravity field within a standard deviation of 1.26 mGal. The density in the crystalline crust increases with depth from 2.65 g/cm3 up to the highest value of 2.95 g/cm3 near the bottom of the crust. The Conrad interface is identified as a density jump of about 0.05 g/cm3. The average density of the crust in MQL is clearly lower than the density in the formations on both sides. Starting from a combined Airy-Pratt isostatic compensation model, a partly compensated crust is found below MQL, suggesting future growth of the crust, unlike the Ordos and Sichuan basins that will remain stable. On the basis of the density and isostatic state of the crust and additional seismological research, such as the P-wave velocity model and Poisson's ratio, it is concluded that the lower crust delamination is a reasonable interpretation for the geophysical characteristics below the Qinling Orogen.

  14. A method for the retrieval of atomic oxygen density and temperature profiles from ground-based measurements of the O(+)(2D-2P) 7320 A twilight airglow

    Science.gov (United States)

    Fennelly, J. A.; Torr, D. G.; Richards, P. G.; Torr, M. R.; Sharp, W. E.

    1991-01-01

    This paper describes a technique for extracting thermospheric profiles of the atomic-oxygen density and temperature, using ground-based measurements of the O(+)(2D-2P) doublet at 7320 and 7330 A in the twilight airglow. In this method, a local photochemical model is used to calculate the 7320-A intensity; the method also utilizes an iterative inversion procedure based on the Levenberg-Marquardt method described by Press et al. (1986). The results demonstrate that, if the measurements are only limited by errors due to Poisson noise, the altitude profiles of neutral temperature and atomic oxygen concentration can be determined accurately using currently available spectrometers.

  15. Low bone mineral density and peripheral blood monocyte activation profile in calcium stone formers with idiopathic hypercalciuria.

    Science.gov (United States)

    Ghazali, A; Fuentès, V; Desaint, C; Bataille, P; Westeel, A; Brazier, M; Prin, L; Fournier, A

    1997-01-01

    Calcium stone formers (CaSF) with idiopathic hypercalciuria (IH) have been shown to have decreased bone mineral density (BMD). The mechanism of their bone loss remains obscure. Monokines like interleukin-1 beta (IL-1 beta), IL-6, tumor necrosis factor-alpha (TNF-alpha), and granulocyte macrophage stimulating factor (GM-CSF) are involved in bone remodeling, but only IL-1 excess has been incriminated in the bone loss of CaSF with IH. Therefore, to more precisely delineate the role of monocyte activation in the pathogenesis of bone loss in these patients, we studied the production of IL-1 beta, IL-6, TNF-alpha, and GM-CSF by unstimulated or lipopolysaccharide (LPS)-stimulated cultured peripheral blood monocytes in 15 CaSF with IH, in 10 CaSF with dietary calcium-dependent hypercalciuria (DH), and in 10 healthy controls (C). Cytokines were measured in the culture medium by sensitive enzyme-linked immunosorbent assay and vertebral BMD by single energy computed tomography. The decrease of vertebral BMD in IH compared with DH, was confirmed (Z score: -1.2 +/- 0.2 vs. -0.5 +/- 0.2; P = 0.04; Mann-Whitney). In the supernatant of unstimulated peripheral blood monocytes, IL-1 beta and TNF-alpha levels were higher in IH than in C (respectively, 40 +/- 21 vs. 7 +/- 1 pg/mL, P = 0.008 and 236 +/- 136 vs. 39 +/- 23 pg/mL, P = 0.03); those of GM-CSF were greater in IH than in DH and C (respectively, 52 +/- 27 vs. 6 +/- 2, P = 0.04 and 6 +/- 2 pg/mL, P = 0.01) and those of IL-6 were not significantly different among the groups. After in vitro stimulation by LPS (10 micrograms/mL), the levels of the various monokines were not significantly different. In IH patients, the post-LPS levels of IL-6 were negatively correlated to vertebral BMD (n = 15, Z = -1.97, P = 0.04; Spearman), whereas those of GM-CSF were positively related to vertebral BMD (n = 15, Z = 2.01, P = 0.04). In this study, calcium stone formers with IH have bone mineral decrease and a particular profile of peripheral

  16. Influence of the Laser Spot Size, Focal Beam Profile, and Tissue Type on the Lipid Signals Obtained by MALDI-MS Imaging in Oversampling Mode

    Science.gov (United States)

    Wiegelmann, Marcel; Dreisewerd, Klaus; Soltwisch, Jens

    2016-12-01

    To improve the lateral resolution in matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) beyond the dimensions of the focal laser spot oversampling techniques are employed. However, few data are available on the effect of the laser spot size and its focal beam profile on the ion signals recorded in oversampling mode. To investigate these dependencies, we produced 2 times six spots with dimensions between 30 and 200 μm. By optional use of a fundamental beam shaper, square flat-top and Gaussian beam profiles were compared. MALDI-MSI data were collected using a fixed pixel size of 20 μm and both pixel-by-pixel and continuous raster oversampling modes on a QSTAR mass spectrometer. Coronal mouse brain sections coated with 2,5-dihydroxybenzoic acid matrix were used as primary test systems. Sizably higher phospholipid ion signals were produced with laser spots exceeding a dimension of 100 μm, although the same amount of material was essentially ablated from the 20 μm-wide oversampling pixel at all spot size settings. Only on white matter areas of the brain these effects were less apparent to absent. Scanning electron microscopy images showed that these findings can presumably be attributed to different matrix morphologies depending on tissue type. We propose that a transition in the material ejection mechanisms from a molecular desorption at large to ablation at smaller spot sizes and a concomitant reduction in ion yields may be responsible for the observed spot size effects. The combined results indicate a complex interplay between tissue type, matrix crystallization, and laser-derived desorption/ablation and finally analyte ionization.

  17. Compositional Shift in Fatty Acid Profiles of Lipids Obtained from Oleaginous Yeasts upon the Addition of Essential Oil from Citrus sinensis L.

    Science.gov (United States)

    Uprety, Bijaya K; Rakshit, Sudip K

    2017-05-05

    Tailoring lipids from oleaginous yeasts to contain specific types of fatty acid is of considerable interest to food, fuel, and pharmaceutical industries. In this study, the essential oil obtained from Citrus sinesus L. has been used to alter the fatty acid composition of two common oleaginous yeasts, Rhodosporidium toruloides and Cryptococcus curvatus. With increasing levels of essential oil in the medium, the metabolic flux of the fatty acid biosynthesis pathway shifted towards saturated fatty acid production. Essential oil reduced the activities of elongase and ∆9 desaturase. This made the lipid obtained from both these yeasts rich in saturated fatty acids. At certain specific concentrations of the essential oil in the medium, the lipid obtained from R. toruloides and C. curvatus cultures was similar to mahuwa butter and palm oil, respectively. Limonene is the major constituents of orange essential oil. Its effect on one of the oleaginous yeasts, R. toruloides, was also studied separately. Effects similar to orange essential oil were obtained with limonene. Thus, we can conclude that limonene in orange essential oil brings about compositional change of microbial lipid produced in this organism.

  18. High energy emission of GRB 130821A: Constraining the density profile of the circum-burst medium as well as the initial Lorentz factor of the outflow

    Energy Technology Data Exchange (ETDEWEB)

    Liang, Yun-Feng; Zhou, Bei; He, Hao-Ning; Fan, Yi-Zhong; Wei, Da-Ming [Key laboratory of Dark Matter and Space Astronomy, Purple Mountain Observatory, Chinese Academy of Sciences, Nanjing 210008 (China); Tam, Pak-Hin Thomas, E-mail: phtam@phys.nthu.edu.tw [Institute of Astronomy and Department of Physics, National Tsing Hua University, Hsinchu 30013, Taiwan (China)

    2014-02-01

    GRB 130821A was detected by Fermi-GBM/LAT, Konus-WIND, SPI-ACS/INTEGRAL, RHESSI and Mars Odyssey-HEND. Although the data of GRB 130821A are very limited, we show in this work that the high energy γ-ray emission (i.e., above 100 MeV) alone imposes tight constraint on the density profile of the circum-burst medium as well as the initial Lorentz factor of the outflow. The temporal behavior of the high energy γ-ray emission is consistent with the forward shock synchrotron radiation model, and the circum-burst medium likely has a constant-density profile. The Lorentz factor is about a few hundred, similar to other bright GRBs.

  19. Phytochemical profile, antioxidant and antimicrobial activity of extracts obtained from erva-mate (Ilex paraguariensis) fruit using compressed propane and supercritical CO2.

    Science.gov (United States)

    Fernandes, Ciro E F; Scapinello, Jaqueline; Bohn, Aline; Boligon, Aline A; Athayde, Margareth L; Magro, Jacir Dall; Palliga, Marshall; Oliveira, J Vladimir; Tres, Marcus V

    2017-01-01

    Traditionally, Ilex paraguariensis leaves are consumed in tea form or as typical drinks like mate and terere, while the fruits are discarded processing and has no commercial value. The aim of this work to evaluate phytochemical properties, total phenolic compounds, antioxidant and antimicrobial activity of extracts of Ilex paraguariensis fruits obtained from supercritical CO2 and compressed propane extraction. The extraction with compressed propane yielded 2.72 wt%, whereas with supercritical CO2 1.51 wt% was obtained. The compound extracted in larger amount by the two extraction solvents was caffeine, 163.28 and 54.17 mg/g by supercritical CO2 and pressurized propane, respectively. The antioxidant activity was more pronounced for the supercritical CO2 extract, with no difference found in terms of minimum inhibitory concentration for Staphylococcus aureus for the two extracts and better results observed for Escherichia coli when using supercritical CO2.

  20. FATTY ACIDS PROFILE IN A HIGH CELL DENSITY CULTURE OF ARACHIDONIC ACID-RICH PARIETOCHLORIS INCISA (TREBOUXIOPHYCEAE,CHLOROPHYTA) EXPOSED TO HIGH PFD

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The changes in arachidonic acid (AA) and fatty acids profiles along the growth curve of Parietochloris incisa, a coccoid snow green alga, were studied in a 2.8 cm light-path flat photobioreactor, exposed to strong photon flux density [PFD, 2400 μEmol/(m2*s)]. Sixteen fatty acids were identified by gas chromatography showing that AA was the dominant fatty acid (33%-41%) followedby linoleic acid (17%-21%). AA content was closely investigated with respect tototal fatty acids (TFA), ash free dry weight (AFDW) of cell mass as well as total culture content. These parameters were influenced significantly in a similar manner by culture growth phase, i.e., slightly decreasing in the lag period, gradually increasing in the logarithmic phase, becoming maximal at the early stationary phase, starting to decrease at the late stationary phase, sharply dropping at the decline phase. The increase in AA per culture volume during the logarithmic phase was not only associated with the increase in AFDW but also connected with a corresponding increase in AA/TFA, TFA/AFDW as well as AA/AFDW. The sharp decrease in AA content of the culture during the decline phase was mainly due to the decrease in AA/TFA, TFA/AFDW and AA/AFDW, although AFDW declined only a smallextent. Maximal AA concentration, obtained at the early stationary phase, was 900 mg/L culture volume, and the average daily net increase of AA during 9 days logarithmic growth was 1.7 g/(m2*day). Therefore, harvesting prior to the declinephase in a batch culture, or at steady state in continuous culture mode seems best for high AA production. The latter possibility was also further confirmed bycontinuous culture with 5 gradients of harvesting rate. ``

  1. Activity profiles for marine sponge-associated bacteria obtained by 16S rRNA vs 16S rRNA gene comparisons.

    Science.gov (United States)

    Kamke, Janine; Taylor, Michael W; Schmitt, Susanne

    2010-04-01

    The phylogenetic diversity of microorganisms in marine sponges is becoming increasingly well described, yet relatively little is known about the activities of these symbionts. Given the seemingly favourable environment provided to microbes by their sponge hosts, as indicated by the extraordinarily high abundance of sponge symbionts, we hypothesized that the majority of sponge-associated bacteria are active in situ. To test this hypothesis we compared, for the first time in sponges, 16S rRNA gene- vs 16S rRNA-derived bacterial community profiles to gain insights into symbiont composition and activity, respectively. Clone libraries revealed a highly diverse bacterial community in Ancorina alata, and a much lower diversity in Polymastia sp., which were identified by electron microscopy as a high- and a low-microbial abundance sponge, respectively. Substantial overlap between DNA and RNA libraries was evident at both phylum and phylotype levels, indicating in situ activity for a large fraction of sponge-associated bacteria. This active fraction included uncultivated, sponge-specific lineages within, for example, Actinobacteria, Chloroflexi and Gemmatimonadetes. This study shows the potential of RNA vs DNA comparisons based on the 16S rRNA gene to provide insights into the activity of sponge-associated microorganisms.

  2. Analysis of the Clinical Profile in Patients with Plasmodium falciparum Malaria and Its Association with Parasite Density.

    Science.gov (United States)

    Mangal, Praveen; Mittal, Shilpa; Kachhawa, Kamal; Agrawal, Divya; Rath, Bhabagrahi; Kumar, Sanjay

    2017-01-01

    Malaria remains a major health hazard in the modern world, particularly in developing countries. In Plasmodium falciparum malaria, there is a direct correlation between asexual erythrocytic stage parasite density and disease severity. Accordingly, the correlations between parasite density and various clinical presentations, severity, and outcome were examined in falciparum malaria in India. The study was conducted in a tertiary health-care center in North India. Of 100 cases of falciparum malaria, 65 patients were male and 35 were female. A total of 54 patients were in the uncomplicated group and 46 patients were in the complicated malaria group. Fever, anemia, icterus, splenomegaly, hepatomegaly, and hepatosplenomegaly were common clinical findings. All clinical findings were significantly more common in the complicated malaria group and patients with a high parasite density than in the uncomplicated group and those with a low parasite density. All patients in the uncomplicated malaria group had a parasite density of 5%, and the difference between groups was statistically significant. The incidence of cerebral malaria was significantly higher in cases with a high parasite density; 58.33% mortality was observed in these cases. Cerebral malaria and hyperbilirubinemia was the most frequently encountered combination of complications. In P. falciparum malaria, parasite density was associated with complications and poor clinical outcomes. These results may inform treatment decisions and suggest that a threshold parasite density of 5% is informative.

  3. Comparison of Relative Humidity obtained from SAPHIR on board Megha-Tropiques and Ground based Microwave Radiometer Profiler over an equatorial station

    Science.gov (United States)

    Renju, Ramachandran Pillai; Uma, K. N.; Krishna Moorthy, K.; Mathew, Nizy; Raju C, Suresh

    A comparison has been made between the SAPHIR on board Megha-Tropiques (MT) derived Relative Humidity (RH (%)) with that derived from a ground based multi-frequency Microwave Radiometer Profiler (MRP) observations over an equatorial station Thiruvananthapuram (8.5(°) N and 76.9(°) E) for a one year period. As a first step, the validation of MRP has been made against the radiosonde for two years (2010 and 2011) during the Indian monsoon period July-September. This analysis shows a wet bias below 6 km and dry bias above. The comparison between the MRP and the MT derived RH has been made at five different altitudinal levels (0.75, 2.25, 4.0, 6.25 and 9.2 km range) strictly under clear sky condition. The regression analysis between the two reveals very good correlation (>0.8) in the altitudinal layer of 2.25 to 6.25 km. The differences between the two observations had also been explained interms of percentage of occurrence between MT and the MRP at each altitudinal layer. About 70-80% of the time, the difference in the RH is found to below 10% at first three layer. The RMSE of 2% is observed at almost all the height layers. The differences have been attributed to the different measurement and retrieval techniques involved in the ground based and satellite based measurements. Since MRP frequecy channels are not sensitive to small water vapor variabilities above 6 km, large differences are observed. Radiative Transfer computation for the channels of both MRP and SAPHIR will be carried out to understand the variabilities.

  4. Protein profiles of Taenia solium cysts obtained from skeletal muscles and the central nervous system of pigs: Search for tissue-specific proteins.

    Science.gov (United States)

    Navarrete-Perea, José; Moguel, Bárbara; Bobes, Raúl José; Villalobos, Nelly; Carrero, Julio César; Sciutto, Edda; Soberón, Xavier; Laclette, Juan Pedro

    2017-01-01

    Taeniasis/cysticercosis caused by the tapeworm Taenia solium is a parasite disease transmitted among humans and pigs, the main intermediate host. The larvae/cysts can lodge in several tissues of the pig, i.e. skeletal muscles and different locations of the central nervous system. The molecular mechanisms associated to tissue preferences of the cysts remain poorly understood. The major public health concern about this zoonosis is due to the human infections by the larval form in the central nervous system, causing a highly pleomorphic and debilitating disease known as neurocysticercosis. This study was aimed to explore the 2DE protein maps of T. solium cysts obtained from skeletal muscles and central nervous system of naturally infected pigs. The gel images were analyzed through a combination of PDQuest™ and multivariate analysis. Results showed that differences in the protein patterns of cysts obtained from both tissues were remarkably discrete. Only 7 protein spots were found specifically associated to the skeletal muscle localization of the cysts; none was found significantly associated to the central nervous system. The use of distinct protein fractions of cysts allowed preliminary identification of several tissue-specific antigenic bands. The implications of these findings are discussed, as well as several strategies directed to achieve the complete characterization of this parasite's proteome, in order to extend our understanding of the molecular mechanisms underlying tissue localization of the cysts and to open avenues for the development of immunological tissue-specific diagnosis of the disease.

  5. HPLC-DAD-ESI-MS(2) analytical profile of extracts obtained from purple sweet potato after green ultrasound-assisted extraction.

    Science.gov (United States)

    Zhu, Zhenzhou; Guan, Qingyan; Koubaa, Mohamed; Barba, Francisco J; Roohinejad, Shahin; Cravotto, Giancarlo; Yang, Xinsun; Li, Shuyi; He, Jingren

    2017-01-15

    Ultrasound pre-treatment (UAE) was applied to assist the extraction of valuable compounds (polyphenols (especially anthocyanins), and proteins) from purple sweet potato (PSP). Under optimum conditions (ultrasound time (40min); supplementary hot extraction (80°C) up to 120min; pH: 2.5; ethanol concentration: 58%), the highest concentrations of polyphenols (3.877mg/g), anthocyanins (0.293mg/g), and proteins (0.753mg/g) were found, with minimal specific energy consumption (8406J/mg). Moreover, anthocyanin and non-anthocyanin polyphenols in PSP extract from optimized extraction temperature were identified using HPLC-DAD-ESI-MS(2). The major identified anthocyanins were peonidin-3-caffeoyl-p-hydroxybenzoyl sophoroside-5-glucoside, peonidin-3-(6″-caffeoyl-6‴-feruloyl sophoroside)-5-glucoside, cyanidin-3-caffeoyl-p-hydroxybenzoyl sophoroside-5-glucoside, whereas the major identified non-anthocyanin molecules were quinic acid, chlorogenic acid, caffeic acid, and chlorogenic acid-3-glucose. The amount of the predominant anthocyanin and non-anthocyanin compounds from PSP extract obtained after UAE was higher than that extracted after conventional solvent extraction. The results obtained in this work demonstrated the efficiency of UAE for the recovery of anthocyanins from PSP.

  6. Ceratonia siliqua L. hydroethanolic extract obtained by ultrasonication: antioxidant activity, phenolic compounds profile and effects in yogurts functionalized with their free and microencapsulated forms.

    Science.gov (United States)

    Rached, Irada; Barros, Lillian; Fernandes, Isabel P; Santos-Buelga, Celestino; Rodrigues, Alírio E; Ferchichi, Ali; Barreiro, Maria Filomena; Ferreira, Isabel C F R

    2016-03-01

    Bioactive extracts were obtained from powdered carob pulp through an ultrasound extraction process and then evaluated in terms of antioxidant activity. Ten minutes of ultrasonication at 375 Hz were the optimal conditions leading to an extract with the highest antioxidant effects. After its chemical characterization, which revealed the preponderance of gallotannins, the extract (free and microencapsulated) was incorporated in yogurts. The microspheres were prepared using an extract/sodium alginate ratio of 100/400 (mg mg(-1)) selected after testing different ratios. The yogurts with the free extract exhibited higher antioxidant activity than the samples added with the encapsulated extracts, showing the preserving role of alginate as a coating material. None of the forms significantly altered the yogurt's nutritional value. This study confirmed the efficiency of microencapsulation to stabilize functional ingredients in food matrices maintaining almost the structural integrity of polyphenols extracted from carob pulp and furthermore improving the antioxidant potency of the final product.

  7. Comparison of the bedrock depth from array measurements of Rayleigh waves associated with microtremor and seismic profile obtained the Seismic Reflection Data, Eskisehir Basin, Turkey

    Science.gov (United States)

    Tün, Muammer; Karabulut, Savaş; Özel, Oğuz

    2015-04-01

    Ground motion estimation for future earthquakes is one of the most challenging problems in seismology and earthquake engineering. The bedrock depth has a considerable seismic risk for the urban area of Eskişehir. In this study, multiple station microtremor measurement methods which are more practical, non-distructive, fast and economical compared to seismic reflection method were implemented. These method using microtremor recordings have become a very useful data for microzonation studies because of their simple acquisition and analysis. Extensive ambient noise measurements were performed in the basin of Eskisehir from June 2010 to spring 2012. We use data recorded by a broadband seismometer and digitizer CMG-6TD, Guralp seismometer. Some of the measurement locations, the CMG-6TD sensor was located into 30 cm-deep holes in the ground to avoid strongly wind-generated, long-period noise. Dominant frequency (f), bed-rock depth (h) and shear-wave velocity (Vs) were determined from Spatial Autocorrelation (SPAC) methods. With the SPAC Method, it is possible to constrain the velocity structure underlying the site using microtremor array measurements. The results obtained were compared to the 96-channel seismic reflection data with explosive energy source. Several seismic reflection surveys with P-Gun seismic source have been performed on the same place with array measurements. We used two types of seismic sources: 36 cartridge Gun. Shot interval was 10 meters, group interval (one geophone per group, 48 geophones in total) was 10 meters, near offset was 10 meters, far offset was 480 meters, CDP interval was 5 meters. We adapted the 'Off-End Spread' technique while using the Gun. Reflection images within the sedimentary section correlate well with the velocity structure obtained from SPAC.

  8. The large-scale correlations of multi-cell densities and profiles, implications for cosmic variance estimates

    CERN Document Server

    Codis, Sandrine; Pichon, Christophe

    2016-01-01

    In order to quantify the error budget in the measured probability distribution functions of cell densities, the two-point statistics of cosmic densities in concentric spheres is investigated. Bias functions are introduced as the ratio of their two-point correlation function to the two-point correlation of the underlying dark matter distribution. They describe how cell densities are spatially correlated. They are computed here via the so-called large deviation principle in the quasi-linear regime. Their large-separation limit is presented and successfully compared to simulations for density and density slopes: this regime is shown to be rapidly reached allowing to get sub-percent precision for a wide range of densities and variances. The corresponding asymptotic limit provides an estimate of the cosmic variance of standard concentric cell statistics applied to finite surveys. More generally, no assumption on the separation is required for some specific moments of the two-point statistics, for instance when pre...

  9. Heterogeneous profiles of a factor that renders neutrophils cytotoxic obtained from a concanavalin A-stimulated spleen cell culture in partial purification process

    Energy Technology Data Exchange (ETDEWEB)

    Fujii, Y.; Inoue, T.; Ito, M.; Kimura, S.; Fuyama, S.; Arai, S.; Naiki, M.; Sendo, F.

    1986-05-15

    Concanavalin A (Con A)-stimulated rat spleen cells were cultured in a serum-free conditioned medium. This culture supernatant contained a certain factor(s) that renders neutrophil cytotoxic for various tumor cells. The factor was tentatively termed neutrophil-activating factor (NAF). NAF activity was eluted in broad fractions by the ion exchange chromatography and the gel filtration. Moreover, on the Con A column, some NAF activities were bound to the column, but other activities passed through the column. These results showed the heterogeneity or polydispersity of NAF activity in both molecular size and charge-based separation properties. Monoclonal antibodies were produced by fusing BALB/c myeloma cells (P3-X63 Ag8.653) with spleen cells from syngeneic mice immunized with partially purified NAF (pNAF) obtained from the gel filtration. Absorbent beads which were linked with one monoclonal antibody (ANAF-10) partially absorbed NAF activity from supernatants of a Con A-stimulated spleen cell culture. By further purification of pNAF the NAF activity was concentrated about 10,000-fold. Heterogeneity of NAF activity, however, did not disappear in even this affinity chromatography. On the other hand, /sup 125/I-labeled material of the final product migrated to one major band corresponding with an m.w. of about 20,000 as determined by SDS-PAGE analysis, and NAF activity was detected in the same band.

  10. Genetic profiles of fluoroquinolone-resistant Escherichia coli isolates obtained from patients with cystitis: phylogeny, virulence factors, PAIusp subtypes, and mutation patterns.

    Science.gov (United States)

    Takahashi, Akira; Muratani, Tetsuro; Yasuda, Mitsuru; Takahashi, Satoshi; Monden, Koichi; Ishikawa, Kiyohito; Kiyota, Hiroshi; Arakawa, Soichi; Matsumoto, Tetsuro; Shima, Hiroki; Kurazono, Hisao; Yamamoto, Shingo

    2009-03-01

    The low virulence of quinolone- and fluoroquinolone-resistant Escherichia coli strains is known, although the reasons for this remain unclear. We surveyed the mutation patterns of quinolone resistance determining regions (QRDRs), phylogenetic distribution, prevalence of 18 urovirulence genes, and PAIusp subtypes in 89 fluoroquinolone-resistant E. coli (FQREC) isolates obtained from patients with cystitis and compared them with those of their fluoroquinolone-susceptible counterparts (FQSEC). Phylogenetic group B2 was significantly less prevalent in FQREC than in FQSEC (49% versus 78%; P=0.0138), but it still dominated, followed by phylogroup D (35%), in FQREC. When the prevalences of virulence factor (VF) genes were compared between FQREC and FQSEC, sfa/foc, cnf1, hly, kpsMT, ompT, ibeA, usp, and iroN showed significantly lower prevalences in FQREC than in FQSEC (1.1% versus 24% [Presistance, e.g., mutations in QRDRs, might be a specific event in limited strains, such as those that possess PAIusp subtype 2a in phylogroup B2.

  11. The Secular Evolution Of Disc Galaxies And The Origin Of Exponential And Double Exponential Surface Density Profiles

    Science.gov (United States)

    Elmegreen, Bruce G.

    2016-10-01

    Exponential radial profiles are ubiquitous in spiral and dwarf Irregular galaxies, but the origin of this structural form is not understood. This talk will review the observations of exponential and double exponential disks, considering both the light and the mass profiles, and the contributions from stars and gas. Several theories for this structure will also be reviewed, including primordial collapse, bar and spiral torques, clump torques, galaxy interactions, disk viscosity and other internal processes of angular momentum exchange, and stellar scattering off of clumpy structure. The only process currently known that can account for this structure in the most theoretically difficult case is stellar scattering off disks clumps. Stellar orbit models suggest that such scattering can produce exponentials even in isolated dwarf irregulars that have no bars or spirals, little shear or viscosity, and profiles that go out too far for the classical Mestel case of primordial collapse with specific angular momentum conservation.

  12. Plasma fasting and nonfasting triglycerides and high-density lipoprotein cholesterol in atherosclerotic stroke: different profiles according to low-density lipoprotein cholesterol.

    Science.gov (United States)

    Kim, Suk Jae; Park, Yun Gyoung; Kim, Ji Hyun; Han, Yun Kyung; Cho, Hong Keun; Bang, Oh Young

    2012-08-01

    Although low-density lipoprotein cholesterol (LDL-C) is the main lipid target for cardiovascular risk reduction, recent studies suggest that other lipid indicies are also associated with vascular events. We hypothesized that the association of triglycerides (TG) and high-density lipoprotein cholesterol (HDL-C) with atherosclerotic stroke (AS) differs depending on LDL-C levels. Data prospectively collected on subjects admitted with acute ischemic stroke to a university medical center were analyzed. We divided the patients into AS and non-atherosclerotic stroke (NAS) groups and independent association of lipid parameters and genetic influences of apolipoprotein A5 (ApoA5) polymorphisms with AS were evaluated. Of 268 patients, 160 (59.7%) were classified with AS and 108 (40.3%) were classified with NAS. Vascular risk factors were more prevalent in AS patients than in those with NAS; additionally, AS patients' anthropometric indexes and laboratory findings showed that they were prone to atherosclerosis. AS was independently associated with fasting TG (OR per 10 mg/dL increase, 1.38; 95% CI, 1.16-1.64; OR for highest vs. lowest tertile, 12.85; 95% CI, 3.31-49.85), HDL-C (OR per 10 mg/dL increase, 0.61; 95% CI, 0.42-0.88; OR for lowest vs. highest tertile, 4.28; 95% CI, 1.16-15.86), and nonfasting TG (OR per 10 10 mg/dL increase, 1.25; 95% CI, 1.11-1.42; OR for highest vs. lowest tertile, 8.20; 95% CI, 1.98-33.88) only among patients with LDL <100 mg/dL. No interaction was observed between fasting and nonfasting TG and ApoA5 polymorphisms. In conclusion, fasting and nonfasting TG and HDL-C were associated with AS only when patients had low levels of LDL-C. Non-LDL-C may have an additional role in addition to the LDL-C levels in AS development. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  13. Determinación de la densidad de entrecruzamiento de poliuretanos obtenidos a partir de aceite de ricino modificado por transesterificación Determination of crosslink density of polyurethanes obtained from castor oil modified by transesterification

    Directory of Open Access Journals (Sweden)

    Manuel F. Valero

    2009-01-01

    Full Text Available Se obtuvo una gama de polioles a partir del aceite de ricino modificado por transesterificación con pentaeritriol y glicerina. Los productos resultantes fueron caracterizados físico-químicamente. Se sintetizaron elastómeros de poliuretano a partir de los polioles derivados del aceite de ricino modificado. La densidad de entrecruzamiento se determinó por ensayos de hinchamiento a partir de la ecuación de Flory-Rehner apoyada en la espectroscopia MALDI TOF MS para determinar la estructura química de la unidad repetitiva promedio del poliuretano. Se estudió la variación de la densidad de entrecruzamiento de los poliuretanos con base en el índice de hidroxilo del poliol utilizado en la síntesis. Los resultados muestran que los PU obtenidos a través de la modificación del aceite con pentaeritriol tienen una mayor densidad de entrecruzamiento que los PU obtenidos a partir del aceite original y de los polioles derivados de la reacción de transesterificación del aceite con glicerina, debido a que estos polioles poseen una mayor funcionalidad hidroxílica.Two series of polyols were obtained from castor oil modified by transesterification with various amounts of pentaerythritol and glycerol. The resultant polyol properties were characterized as a function of the hydroxyl functionality. Polyurethane elastomers (PU were synthesized from the two series of polyols obtained. The crosslink density of those polyurethanes was determined by swelling tests data adjusted to the Flory-Rehner's equation and according to the elasticity theory. The variation of the crosslink density of polyurethanes was studied by following the hydroxyl value of the modified polyol utilized in the synthesis and based on the average structure of each polyurethane repeating unit, as determined by the method of matrix-assisted laser desorption/ionization time-of-flight mass spectroscopy (MALDI TOF MS. The results show that the PU obtained through castor oil modified with

  14. Influence of the fluid structure on the binding potential: Comparing liquid drop profiles from density functional theory with results from mesoscopic theory

    Science.gov (United States)

    Hughes, Adam P.; Thiele, Uwe; Archer, Andrew J.

    2017-02-01

    For a film of liquid on a solid surface, the binding potential g(h) gives the free energy as a function of the film thickness h and also the closely related (structural) disjoining pressure Π =-∂g /∂h . The wetting behaviour of the liquid is encoded in the binding potential and the equilibrium film thickness corresponds to the value at the minimum of g(h). Here, the method we developed in the work of Hughes et al. [J. Chem. Phys. 142, 074702 (2015)], and applied with a simple discrete lattice-gas model, is used with continuum density functional theory (DFT) to calculate the binding potential for a Lennard-Jones fluid and other simple liquids. The DFT used is based on fundamental measure theory and so incorporates the influence of the layered packing of molecules at the surface and the corresponding oscillatory density profile. The binding potential is frequently input in mesoscale models from which liquid drop shapes and even dynamics can be calculated. Here we show that the equilibrium droplet profiles calculated using the mesoscale theory are in good agreement with the profiles calculated directly from the microscopic DFT. For liquids composed of particles where the range of the attraction is much less than the diameter of the particles, we find that at low temperatures g(h) decays in an oscillatory fashion with increasing h, leading to highly structured terraced liquid droplets.

  15. The Effect of Air Density on Sand Transport Structures and the Adobe Abrasion Profile: A Field Wind-Tunnel Experiment Over a Wide Range of Altitude

    Science.gov (United States)

    Han, Qingjie; Qu, Jianjun; Dong, Zhibao; Zu, Ruiping; Zhang, Kecun; Wang, Hongtao; Xie, Shengbo

    2013-11-01

    Aeolian sand transport results from interactions between the surface and the airflow above. Air density strongly constrains airflow characteristics and the resulting flow of sand, and therefore should not be neglected in sand transport models. In the present study, we quantify the influence of air density on the sand flow structure, sand transport rate, adobe abrasion profiles, and abrasion rate using a portable wind-tunnel in the field. For a given wind speed, the flow's ability to transport sand decreases at low air density, so total sand transport decreases, but the saltation height increases. Thus, the damage to human structures increases compared with what occurs at lower altitudes. The adobe abrasion rate by the cloud of blowing sand decreases exponentially with increasing height above the surface, while the wind erosion and dust emission intensity both increase with increasing air density. Long-term feedback processes between air density and wind erosion suggest that the development of low-altitude areas due to long-term deflation plays a key role in dust emission, and will have a profound significance for surface Aeolian processes and geomorphology.

  16. Measurements of electron density and temperature profiles in plasma produced by Nike KrF laser for laser plasma instability research

    Science.gov (United States)

    Oh, Jaechul; Weaver, J. L.; Karasik, M.; Chan, L. Y.

    2015-08-01

    A grid image refractometer (GIR) has been implemented at the Nike krypton fluoride laser facility of the Naval Research Laboratory. This instrument simultaneously measures propagation angles and transmissions of UV probe rays (λ = 263 nm, Δt = 10 ps) refracted through plasma. We report results of the first Nike-GIR measurement on a CH plasma produced by the Nike laser pulse (˜1 ns FWHM) with the intensity of 1.1 × 1015 W/cm2. The measured angles and transmissions were processed to construct spatial profiles of electron density (ne) and temperature (Te) in the underdense coronal region of the plasma. Using an inversion algorithm developed for the strongly refracted rays, the deployed GIR system probed electron densities up to 4 × 1021 cm-3 with the density scale length of 120 μm along the plasma symmetry axis. The resulting ne and Te profiles are verified to be self-consistent with the measured quantities of the refracted probe light.

  17. Measurements of Laser Plasma Instability (LPI) and Electron Density/Temperature Profiles in Plasmas Produced by the Nike KrF Laser

    Science.gov (United States)

    Oh, Jaechul; Weaver, J. L.; Serlin, V.; Obenschain, S. P.

    2016-10-01

    We will present results of simultaneous measurements of LPI-driven light scattering and density/temperature profiles in CH plasmas produced by the Nike krypton fluoride laser (λ = 248 nm). The primary diagnostics for the LPI measurement are time-resolved spectrometers with absolute intensity calibration in spectral ranges relevant to the optical detection of stimulated Raman scattering or two plasmon decay. The spectrometers are capable of monitoring signal intensity relative to thermal background radiation from plasma providing a useful way to analyze LPI initiation. For further understanding of LPI processes, the recently implemented grid image refractometer (Nike-GIR)a is used to measure the coronal plasma profiles. In this experiment, Nike-GIR is equipped with a 5th harmonic probe laser (λ = 213 nm) in attempt to probe into a high density region over the previous peak density with λ = 263 nm probe light ( 4 ×1021 cm-3). The LPI behaviors will be discussed with the measured data sets. Work supported by DoE/NNSA.

  18. Improving lipoprotein profiles by liver-directed gene transfer of low density lipoprotein receptor gene in hypercholesterolaemia mice

    Indian Academy of Sciences (India)

    HAILONG OU; QINGHAI ZHANG; JIA ZENG

    2016-06-01

    The defect of low density lipoprotein receptor disturbs cholesterol metabolism and causes familial hypercholesterolaemia(FH). In this study, we directly delivered exogenousLdlrgene into the liver of FH model mice (Ldlr − / −) by lentiviral genetransfer system. The results showed that theLdlrgene controlled by hepatocyte-specific human thyroxine-binding globulin(TBG) promoter successfully and exclusively expressed in livers. We found that, although, the content of high density lipopro-tein in serum was not significantly affected by theLdlrgene expression, the serum low density lipoprotein level was reducedby 46%, associated with a 30% and 28% decrease in triglyceride and total cholesterol, respectively, compared to uninjectedLdlr − / −mice. Moreover, the TBG directed expression ofLdlrsignificantly decreased the lipid accumulation in liver andreduced plaque burden in aorta (32%). Our results indicated that the hepatocyte-specific expression ofLdlrgene strikinglylowered serum lipid levels and resulted in amelioration of hypercholesterolaemia.

  19. Forward Modeling of the 2003 November 14 Titan Occultation: New Retrievals of Temperature, Density and Opacity Profiles from about 350 to 500 km

    Science.gov (United States)

    Young, E. F.; Zalucha, A.

    2012-04-01

    On 2003 November 14, Titan occulted a relatively bright star (V = 10.7). This event was observed from La Palma Observatory using ULTRACAM in three simultaneous wavelengths (358, 487 and 758 nm), as reported by Zalucha et al. (2007). The event was near-central, but only the long-wavelength light curves show a central flash. Zalucha et al. (2007) extracted temperature profiles from 350 to 485 km, estimated the altitudes where line-of-sight aerosol optical depths are one in the three ULTRACAM filters and fit the three-peaked central flash feature to atmospheric shape models that are comparable to those used by Hubbard et al. (1993) in the 28 Sgr occultation. We now use a more flexible forward-modeling approach to re-examine the ULTRACAM light curves. The output of this effort is a thin-screen representation of Titan’s upper atmosphere consisting of line-of-sight opacities and phase delays - it is a flexible technique to simultaneously retrieve extinction and refractivity profiles and bulk atmospheric shape. We will present temperature, density and opacity profiles that are consistent with the retrieved thin-screen model and compare model light curves generated from HASI temperature profiles to the occultation observations. References: Zalucha, A., et al.: "The 2003 November 14 occultation by Titan of TYC 1343-1865-1 II. Analysis of light curves". Icarus, Vol. 197, pp. 503-518, 2007.

  20. Electron density profiles in the nighttime high-latitude lower ionosphere, artificially disturbed by high-power radio waves

    Science.gov (United States)

    Gokov, A. M.; Martynenko, S. I.; Misiura, V. A.; Piven, L. A.; Somov, V. G.; Fedorenko, Iu. P.; Chernogor, L. F.; Shemet, A. S.

    1982-10-01

    The method of partial reflections detected increases of electron temperature to 50% at heights of 67-71 km. The electron density decreased under the effect of high-power radio waves (9 MW effective pulse power) by 30-40% at 68-72 km, while it increased by several tens of percent at 76-85 km.

  1. Real Time Extraction Kinetics of Electro Membrane Extraction Verified by Comparing Drug Metabolism Profiles Obtained from a Flow-Flow Electro Membrane Extraction-Mass Spectrometry System with LC-MS

    DEFF Research Database (Denmark)

    Fuchs, David; Jensen, Henrik; Pedersen-Bjergaard, Stig

    2015-01-01

    A simple to construct and operate, "dip-in" electromembrane extraction (EME) probe directly coupled to electrospray ionization-mass spectrometry (ESI-MS) for rapid extraction and real time analysis of various analytes was developed. The setup demonstrated that EME-MS can be used as a viable...... alternative to conventional protein precipitation followed by liquid chromatography-mass spectrometry (LC-MS) for studying drug metabolism. Comparison of EME-MS with LC-MS for drug metabolism analysis demonstrated for the first time that real time extraction of analytes by EME is possible. Metabolism kinetics...... were investigated for three different drugs: amitriptyline, promethazine, and methadone. By comparing the EME-MS extraction profiles of the drug substances and formed drug metabolites with the metabolism profiles obtained by conventional protein precipitation followed by LC-MS good correlation...

  2. Density profiles of small Dirac operator eigenvalues for two color QCD at nonzero chemical potential compared to matrix models

    Energy Technology Data Exchange (ETDEWEB)

    Akemann, Gernot [Service de Physique Theorique, CEA/DSM/SPhT Saclay, Unite associee CNRS/SPM/URA 2306, F-91191 Gif-sur-Yvette Cedex (France); Department of Mathematical Sciences, Brunel University West London, Uxbridge, UB8 3PH (United Kingdom); Bittner, Elmar [Institut fuer Theoretische Physik, Universitaet Leipzig, Augustplatz 10/11, D-04109 Leipzig (Germany); Lombardo, Maria-Paola [INFN-Laboratori Nazionali di Frascati, I-00044 Frascati (Italy); Markum, Harald [Atominstitut, Technische Universitaet Wien, A-1040 Vienna (Austria); Pullirsch, Rainer [Atominstitut, Technische Universitaet Wien, A-1040 Vienna (Austria)

    2005-03-15

    We investigate the eigenvalue spectrum of the staggered Dirac matrix in two color QCD at finite chemical potential. The profiles of complex eigenvalues close to the origin are compared to a complex generalization of the chiral Gaussian Symplectic Ensemble, confirming its predictions for weak and strong non-Hermiticity. They differ from the QCD symmetry class with three colors by a level repulsion from both the real and imaginary axis.

  3. A model to obtain an optimum erbium desity for gain increasing in EDFA

    Directory of Open Access Journals (Sweden)

    E. Arzi

    2003-12-01

    Full Text Available   In this paper, we suggest a novel model, based on input pump power and wave guidestructure, to calculate the Er-density profile in Erbium doped fiber amplifiers. This optimization is carried out for both SMF and DSF fibers. These optimized profiles have a Gaussian-like shape. Using the SMF optimized Er-density profile, high gain enhancement is obtained in a relatively short length of fibers. On the other hand, the DSF optimized profile shows small changes in the gain, which agrees with the previously report on other method of gain enhancement. This model is applicable to all active waveguides and any other dopant as well .

  4. Hematological profile of juvenile European catfish (Silurus glanis reared under different stocking densities in recirculating system conditions

    Directory of Open Access Journals (Sweden)

    Sandita Placinta

    2014-05-01

    Full Text Available   The aim of present study was to evaluate the hematological parameters and the absolute number of leukocytes of European catfish (Silurus glanis maintained in different technological conditions induced by applied stocking densities. The experiment was conducted over a period of 32 days. A number of 450 European catfish, with an average weight of 158,9± 0,26 g, were distributed in four rearing units, in order to create different stocking densities as follows: V1- 14,28 kg/m3,  V2 – 28,59 kg/m3, V3 – 42,97 kg/m3 and V4- 57,06 kg/m3. The following hematological parameters were determined: RBC, Ht, Hb, MCV, MCH and MCHC. A decrease of RBC and higher values of MCH and MCHC were observed at V4, while at V1 an increase in RBC and lower MCV, MCH values can be seen. Regarding the absolute number of leukocytes, no significant statistical differences were registered between the applied stocking densities (p>0.05. However, there was a slight increase of leukocyte number with increasing stocking density (240,01 x103cel./mm3 at V4,  respectively 189,64 x103cel./mm3 at V1. It can be concluded from hematological parameters analysis that a stocking density of 60 kg/m3 seems to be out of the optimal range for catfish growth, in current growth conditions.  

  5. Human synaptic plasticity gene expression profile and dendritic spine density changes in HIV-infected human CNS cells: role in HIV-associated neurocognitive disorders (HAND.

    Directory of Open Access Journals (Sweden)

    Venkata Subba Rao Atluri

    Full Text Available HIV-associated neurocognitive disorders (HAND is characterized by development of cognitive, behavioral and motor abnormalities, and occur in approximately 50% of HIV infected individuals. Our current understanding of HAND emanates mainly from HIV-1 subtype B (clade B, which is prevalent in USA and Western countries. However very little information is available on neuropathogenesis of HIV-1 subtype C (clade C that exists in Sub-Saharan Africa and Asia. Therefore, studies to identify specific neuropathogenic mechanisms associated with HAND are worth pursuing to dissect the mechanisms underlying this modulation and to prevent HAND particularly in clade B infection. In this study, we have investigated 84 key human synaptic plasticity genes differential expression profile in clade B and clade C infected primary human astrocytes by using RT(2 Profile PCR Array human Synaptic Plasticity kit. Among these, 31 and 21 synaptic genes were significantly (≥3 fold down-regulated and 5 genes were significantly (≥3 fold up-regulated in clade B and clade C infected cells, respectively compared to the uninfected control astrocytes. In flow-cytometry analysis, down-regulation of postsynaptic density and dendrite spine morphology regulatory proteins (ARC, NMDAR1 and GRM1 was confirmed in both clade B and C infected primary human astrocytes and SK-N-MC neuroblastoma cells. Further, spine density and dendrite morphology changes by confocal microscopic analysis indicates significantly decreased spine density, loss of spines and decreased dendrite diameter, total dendrite and spine area in clade B infected SK-N-MC neuroblastoma cells compared to uninfected and clade C infected cells. We have also observed that, in clade B infected astrocytes, induction of apoptosis was significantly higher than in the clade C infected astrocytes. In conclusion, this study suggests that down-regulation of synaptic plasticity genes, decreased dendritic spine density and induction of

  6. Validation of the concentration profiles obtained from the near infrared/multivariate curve resolution monitoring of reactions of epoxy resins using high performance liquid chromatography as a reference method.

    Science.gov (United States)

    Garrido, M; Larrechi, M S; Rius, F X

    2007-03-07

    This paper reports the validation of the results obtained by combining near infrared spectroscopy and multivariate curve resolution-alternating least squares (MCR-ALS) and using high performance liquid chromatography as a reference method, for the model reaction of phenylglycidylether (PGE) and aniline. The results are obtained as concentration profiles over the reaction time. The trueness of the proposed method has been evaluated in terms of lack of bias. The joint test for the intercept and the slope showed that there were no significant differences between the profiles calculated spectroscopically and the ones obtained experimentally by means of the chromatographic reference method at an overall level of confidence of 5%. The uncertainty of the results was estimated by using information derived from the process of assessment of trueness. Such operational aspects as the cost and availability of instrumentation and the length and cost of the analysis were evaluated. The method proposed is a good way of monitoring the reactions of epoxy resins, and it adequately shows how the species concentration varies over time.

  7. Hydraulic conductivity obtained by instantaneous profile method using retention curve and neutron probes and Genuchten model; Condutividade hidraulica obtida pelo metodo do perfil instantaneo utilizando curva de retencao e sonda de neutrons e pelo modelo de Genuchten

    Energy Technology Data Exchange (ETDEWEB)

    Berretta, Ana Lucia Olmedo

    1999-07-01

    The hydraulic conductivity is one of the most important parameters to understand the movement of water in the unsaturated zone. Reliable estimations are difficult to obtain, once the hydraulic conductivity is highly variable. This study was carried out at 'Escola Superior de Agricultura Luiz de Queiroz', Universidade de Sao Paulo, in a Kandiudalfic Eutrudox soil. The hydraulic conductivity was determined by a direct and an indirect method. The instantaneous profile method was described and the hydraulic conductivity as a function of soil water content was determined by solving the Richards equation. Tensiometers were used to estimate the total soil water potential, and the neutron probe and the soil retention curve were used to estimate soil water content in the direct method. The neutron probe showed to be not adequately sensible to the changes of soil water content in this soil. Despite of the soil retention curve provides best correlation values to soil water content as a function of water redistribution time, the soil water content in this soil did not vary too much till the depth of 50 cm, reflecting the influence of the presence of a Bt horizon. The soil retention curve was well fitted by the van Genuchten model used as an indirect method. The values of the van Genuchten and the experimental relative hydraulic conductivity obtained by the instantaneous profile method provided a good correlation. However, the values estimated by the model were always lower than that ones obtained experimentally. (author)

  8. A direct dynamical measurement of the Milky Way's disk surface density profile, disk scale length, and dark matter profile at 4 kpc < R < 9 kpc

    CERN Document Server

    Bovy, Jo

    2013-01-01

    We present and apply rigorous dynamical modeling with which we infer unprecedented constraints on the stellar and dark matter mass distribution within our Milky Way (MW), based on large sets of phase-space data on individual stars. Specifically, we model the dynamics of 16,269 G-type dwarfs from SEGUE, which sample 5 < R/kpc < 12 and 0.3 < |Z|/kpc < 3. We independently fit a parameterized MW potential and a three-integral, action-based distribution function (DF) to the phase-space data of 43 separate abundance-selected sub-populations (MAPs), accounting for the complex selection effects affecting the data. We robustly measure the total surface density within 1.1 kpc of the mid-plane to about 5% over the range 4.5< R/kpc < 9. Using metal-poor MAPs with small radial scale lengths as dynamical tracers probes 4.5 < R/kpc < 7, while MAPs with longer radial scale lengths sample 7 < R/kpc < 9. We measure the mass-weighted Galactic disk scale length to be R_d = 2.15+/-0.14 kpc, in agreem...

  9. Is Lipid Profile Associated with Bone Mineral Density and Bone Formation in Subjects with Spinal Cord Injury?

    Directory of Open Access Journals (Sweden)

    Hadis Sabour

    2014-01-01

    Full Text Available Purpose. The association between serum lipids and bone mineral density (BMD has been investigated previously but, up to now, these relationships have not yet been described in spinal cord injury (SCI. We tried to assess the correlation between serum triglyceride (TG, total cholesterol (TC, high-density lipoprotein (HDL, and low-density lipoprotein (LDL and BMD in male subjects with SCI. Methods. Dual-energy X-ray absorptiometry (DXA was used to assess BMD in femoral neck, trochanter, intertrochanteric zone, and lumbar vertebras. Blood samples were taken to measure serums lipids and bone biomarkers including osteocalcin, cross-linked type I collagen (CTX, and bone alkaline phosphatase (BALP. Partial correlation analysis was used to evaluate the relationships between mentioned measurements after adjustment for weight and age. Results. We found a positive correlation between HDL and femoral neck BMD (P: 0.004, r=0.33. HDL was negatively correlated with osteocalcin (P: 0.017, r=-0.31 which was not in consistency with its relationship with BMD. TC and LDL were not related to CTX, BALP and BMD. Conclusion. This study does not support a strong association between serum lipids and BMD in subjects with SCI. Moreover it seems that positive association between HDL and BMD is not mediated through increased bone formation.

  10. Free energy partitioning analysis of the driving forces that determine ion density profiles near the water liquid-vapor interface.

    Science.gov (United States)

    Arslanargin, Ayse; Beck, Thomas L

    2012-03-14

    Free energy partitioning analysis is employed to explore the driving forces for ions interacting with the water liquid-vapor interface using recently optimized point charge models for the ions and SPC/E water. The Na(+) and I(-) ions are examined as an example kosmotrope/chaotrope pair. The absolute hydration free energy is partitioned into cavity formation, attractive van der Waals, local electrostatic, and far-field electrostatic contributions. We first compute the bulk hydration free energy of the ions, followed by the free energy to insert the ions at the center of a water slab. Shifts of the ion free energies occur in the slab geometry consistent with the SPC/E surface potential of the water liquid-vapor interface. Then the free energy profiles are examined for ion passage from the slab center to the dividing surface. The profiles show that, for the large chaotropic I(-) ion, the relatively flat total free energy profile results from the near cancellation of several large contributions. The far-field electrostatic part of the free energy, largely due to the water liquid-vapor interface potential, has an important effect on ion distributions near the surface in the classical model. We conclude, however, that the individual forms of the local and far-field electrostatic contributions are expected to be model dependent when comparing classical and quantum results. The substantial attractive cavity free energy contribution for the larger I(-) ion suggests that there is a hydrophobic component important for chaotropic ion interactions with the interface.

  11. Effects of atorvastatin and simvastatin on low-density lipoprotein subfraction profile, low-density lipoprotein oxidizability, and antibodies to oxidized low-density lipoprotein in relation to carotid intima media thickness in familial hypercholesterolemia.

    NARCIS (Netherlands)

    Tits, L.J.H. van; Smilde, T.J.; Wissen, S. van; Graaf, J. de; Kastelein, J.J.P.; Stalenhoef, A.F.H.

    2004-01-01

    BACKGROUND: Little is known about the effects of statins on the quality of circulating low-density lipoprotein (LDL) in relation to atherosclerosis progression. METHODS: In a double-blind, randomized trial of 325 patients with familial hypercholesterolemia (FH), we assessed the effects of high-dose

  12. Liquid drops on a surface: Using density functional theory to calculate the binding potential and drop profiles and comparing with results from mesoscopic modelling

    Science.gov (United States)

    Hughes, Adam P.; Thiele, Uwe; Archer, Andrew J.

    2015-02-01

    The contribution to the free energy for a film of liquid of thickness h on a solid surface due to the interactions between the solid-liquid and liquid-gas interfaces is given by the binding potential, g(h). The precise form of g(h) determines whether or not the liquid wets the surface. Note that differentiating g(h) gives the Derjaguin or disjoining pressure. We develop a microscopic density functional theory (DFT) based method for calculating g(h), allowing us to relate the form of g(h) to the nature of the molecular interactions in the system. We present results based on using a simple lattice gas model, to demonstrate the procedure. In order to describe the static and dynamic behaviour of non-uniform liquid films and drops on surfaces, a mesoscopic free energy based on g(h) is often used. We calculate such equilibrium film height profiles and also directly calculate using DFT the corresponding density profiles for liquid drops on surfaces. Comparing quantities such as the contact angle and also the shape of the drops, we find good agreement between the two methods. We also study in detail the effect on g(h) of truncating the range of the dispersion forces, both those between the fluid molecules and those between the fluid and wall. We find that truncating can have a significant effect on g(h) and the associated wetting behaviour of the fluid.

  13. Comparative study of non-high density lipoproteins cholesterol level and lipid profile in pre-diabetic and diabetic patients.

    Science.gov (United States)

    Banu, Shaheena; Jabir, Nasimudeen R; Manjunath, Nanjappa C; Firoz, C K; Kamal, Mohammad A; Khan, Mohammad S; Tabrez, Shams

    2014-04-01

    The present study compares the role and significance of non-high density lipoproteins (non-HDL) cholesterol level in pre-diabetic and diabetic patients. This study also compares non-HDL cholesterol level between males and females and with different age groups as well. An observational study was conducted among 3830 randomly selected individuals to envisage the association of non-HDL cholesterol and other lipid parameters with age, gender, and diabetic status. On the basis of health status, the subjects were classified as diabetic, pre-diabetic and normal. Fasting blood samples were collected and analyzed on Roche p-800 modular system. Total cholesterol, high density lipoproteins (HDL), low density lipoproteins (LDL) and fasting triglycerides were also measured. From the above mentioned parameters, the level of non-HDL cholesterol level was also calculated. Significant association was observed with non-HDL cholesterol level and all other studied lipid parameters (total cholesterol, HDL, LDL and triglycerides) compared with age and gender of the subjects studied. Moreover, the calculated non-HDL level, total cholesterol and triglycerides were found to be significantly co-related with diabetic status of the patients involved in the study. However, HDL and LDL values did not show any significant association with diabetic status of the patients. In this study, we found that age and gender of the studied subjects are associated with non-HDL cholesterol. Moreover, our data clearly indicates the positive association of non-HDL cholesterol level with pre-diabetic and diabetic status of the patients. Based on our study, we recommend estimation of non-HDL level in routine clinical practice to differentiate pre-diabetic and diabetic patients.

  14. Measurements of Electron Temperature and Density Profiles of Plasmas Produced by Nike KrF Laser for Laser Plasma Instability (LPI) Research

    Science.gov (United States)

    Oh, Jaechul; Weaver, J. L.; Obenschain, S. P.; Schmitt, A. J.; Kehne, D. M.; Karasik, M.; Chan, L.-Y.; Serlin, V.; Phillips, L.

    2012-10-01

    ExperimentsfootnotetextJ. Oh, et al, GO5.4, APS DPP (2010).^,footnotetextJ. L. Weaver, et al, GO5.3, APS DPP (2010). using Nike KrF laser observed LPI signatures from CH plasmas at the laser intensities above ˜1x10^15 W/cm^2. Knowing spatial profiles of temperature (Te) and density (ne) in the underdense coronal region (0 Nike LPI experiment, a side-on grid imaging refractometer (GIR)footnotetextR. S. Craxton, et al, Phys. Fluids B 5, 4419 (1993). is being deployed for measuring the underdense plasma profiles. The GIR will resolve Te and ne in space taking a 2D snapshot of probe laser (λ= 263 nm, δt = 10 psec) beamlets (50μm spacing) refracted by the plasma at a selected time during the laser illumination. Time-resolved spectrometers with an absolute-intensity-calibrated photodiode array and a streak camera will simultaneously monitor light emission from the plasma in spectral ranges relevant to Raman (SRS) and two plasmon decay (TDP) instabilities. The experimental study of effects of the plasma profiles on the LPI initiation will be presented.

  15. Variability of the bottomside (B0, B1) profile parameters of ionospheric electron density over the lower mid-latitude Cyprus and comparisons with IRI-2012 model

    Science.gov (United States)

    Panda, Sampad Kumar; Haralambous, Haris; Mostafa, Md Golam

    2016-07-01

    The present study investigates the variations of the bottomside ionospheric electron density profile thickness (B0) and shape (B1) parameters, deduced from the manually scaled digisonde (DPS-4D) ionograms at the lower mid-latitude Cyprus (Geographic 35°N, 33°E) covering the period 2009-2014. The monthly median hourly values of these parameters during different seasons and solar activity conditions are compared with the International Reference Ionosphere model (IRI-2012) estimations using three different options namely: Bil-2000, Gul-1987, and ABT-2009. To ensure the quiet time profile, the ionograms of the geomagnetically disturbed periods are discarded from the datasets and the storm model in the IRI is intentionally turned off. The statistical studies reveal considerable discrepancies in the observed B0 parameters from the model simulations, though the divergences are minimal around the daytime and during the summer solstice seasons. Nevertheless, B0 with the Gul-1987 option apparently shows closer daytime value during the low solar active summer, whereas the ABT-2009 option manifested relatively better agreement during the high solar active summer months. The characteristic morning, evening, as well as nighttime departure in the model derived B0 parameters are conspicuous in all the seasons in spite of unnoticed perturbations in the B1, suggesting that further improvement in the existing model database is essential with additional in-situ experimental data across the lower mid-latitude region. The important extracts from this study may support in the international efforts of determining the best set of profile parameters for the climatological representation of the ionospheric electron density variation across the globe.

  16. Effect of Stocking Density Stress on the Hematological Profile of Oncorhynchus Mykiss in KashmirTrout Raceways

    Directory of Open Access Journals (Sweden)

    Samina Qadir Charoo

    2014-07-01

    Full Text Available The present research aimed at the investigation into the effect of stocking density on the hematological response of Oncorhynchus mykiss maintained in flow through condition. The stock having a weight of 520.22 ± 48.20 g and 580.25± 52.2 g were stocked in flow through FRP tanks at the stocking density of 38 kg/m3 and 30 kg/ m3 respectively. The sampling of Oncorhynchus mykiss blood from the four variants before and after the experimental trial allowed determination of hematological indices. Red blood cell counts (RBCc, hematocrit values (Hct, hemoglobin concentration (Hb, mean corpuscular volume (MCV, mean corpuscular hemoglobin (MCH and mean corpuscular hemoglobin concentration (MCHC were measured and analyzed, with routine methods used in fish hematology. Differences in hematological parameters were statistically analyzed by Student T test. Physiological stress, induced by maintenance in different technological condition induced by stocking stress, was reflected in the hematological indices (significant increase, p<0.05, RBCc, Hb, Ht, MCV and decrease insignificant, p >0.05 MCH, MCHC with direct implications at the biotechnological level.

  17. Beam Matching to a Plasma Wake Field Accelerator Using a Ramped Density Profile at the Plasma Boundary

    CERN Document Server

    Marsh, Kenneth; Clayton, Chris; Decker, Franz Josef; Deng, Suzhi; Hogan, Mark; Huang Cheng Kun; Iverson, Richard; Johnson, Devon K; Joshi, Chandrashekhar; Katsouleas, Thomas C; Krejcik, Patrick; Lu, Wei; Mori, Warren; Muggli, Patric; Oz, Erdem; Siemann, Robert; Walz, Dieter; Zhou, Miaomiao

    2005-01-01

    An important aspect of plasma wake field accelerators (PWFA) is stable propagation of the drive beam. In the under dense regime, the drive beam creates an ion channel which acts on the beam as a strong thick focusing lens. The ion channel causes the beam to undergo multiple betatron oscillations along the length of the plasma. There are several advantages if the beam size can be matched to a constant radius. First, simulations have shown that instabilities such as hosing are reduced when the beam is matched. Second, synchrotron radiation losses are minimized when the beam is matched. Third, an initially matched beam will propagate with no significant change in beam size in spite of large energy loss or gain. Coupling to the plasma with a matched radius can be difficult in some cases. This paper shows how an appropriate density ramp at the plasma entrance can be useful for achieving a matched beam. Additionally, the density ramp is helpful in bringing a misaligned trailing beam onto the drive beam axis. A plas...

  18. Imaging brain gene expression profiles by antipsychotics: region-specific action of amisulpride on postsynaptic density transcripts compared to haloperidol.

    Science.gov (United States)

    de Bartolomeis, Andrea; Marmo, Federica; Buonaguro, Elisabetta Filomena; Rossi, Rodolfo; Tomasetti, Carmine; Iasevoli, Felice

    2013-11-01

    Induction of motor disorders is considered the clinical landmark differentiating typical from atypical antipsychotics, and has been mainly correlated to dopamine D2 receptors blockade in striatum. This view is challenged by benzamides, such as amisulpride, which display low liability for motor side effects despite being D2/D3 receptors high-affinity blocking agents. These effects have been explained with the prominent presynaptic action of amisulpride or with the fast dissociation at D2 receptors, but there is scarce information on the effects of amisulpride on postsynaptic signaling. We carried out a molecular imaging study of gene expression after acute administration of haloperidol (0.8 mg/kg), amisulpride (10 or 35 mg/kg), or vehicle, focusing on postsynaptic genes that are key regulators of synaptic plasticity, such as Arc, c-fos, Zif-268, Norbin, Homer. The last one has been associated to schizophrenia both in clinical and preclinical studies, and is differentially induced by antipsychotics with different D2 receptors affinity. Topography of gene expression revealed that amisulpride, unlike haloperidol, triggers transcripts expression peak in medial striatal regions. Correlation analysis of gene expression revealed a prevalent correlated gene induction within motor corticostriatal regions by haloperidol and a more balanced gene induction within limbic and motor corticostriatal regions by amisulpride. Despite the selective dopaminergic profile of both compounds, our results demonstrated a differential modulation of postsynaptic molecules by amisulpride and haloperidol, the former impacting preferentially medial regions of striatum whereas the latter inducing strong gene expression in lateral regions. Thus, we provided a possible molecular profile of amisulpride, putatively explaining its "atypical atypicality".

  19. Predicted metabolizable energy density and amino acid profile of the crop contents of free-living scarlet macaw chicks (Ara macao).

    Science.gov (United States)

    Cornejo, J; Dierenfeld, E S; Bailey, C A; Brightsmith, D J

    2012-12-01

    Hand rearing of neonates is a common practice for the propagation of psittacines. However, nutritional requirements for their growth and development are not well understood, and malnutrition is common. We analysed the amino acid (AA) profile of the crop contents of 19 free-living scarlet macaw (Ara macao) chicks, 19-59 days old. Predicted metabolizable energy (PME) density was 16.9 MJ/kg DM and true protein (total AA protein) 8.3 g/MJ PME. Crude protein (CP) was 10.0 g/MJ PME, lower than the requirements of 0- to 12-week-old leghorn chicks but not different than the requirements of growing budgerigars (Melopsittacus undulatus) and lovebirds (Agapornis spp.). The mean concentrations of leucine, isoleucine, threonine, lysine (Lys) and methionine on a PME basis were below the minimum requirements of 0- to 12-week-old leghorn-type chicks. The calculated PME density of the samples did not vary with age. However, there was a significant negative correlation between the average age of the chicks and the Lys concentration. We conclude that the lower CP and AA densities compared with poultry could result from a combination of (i) differences in the essential AA composition of the body tissues, (ii) adaptations that allow the birds to grow on low-protein food sources and (iii) suboptimal nutrition of these free-ranging chicks. © 2011 Blackwell Verlag GmbH.

  20. Ion density and temperature profiles along (XGSM) and across (ZGSM) the magnetotail as observed by THEMIS, Geotail, and ARTEMIS

    Science.gov (United States)

    Artemyev, A. V.; Angelopoulos, V.; Hietala, H.; Runov, A.; Shinohara, I.

    2017-02-01

    Characteristics of the two-dimensional configuration of the magnetotail current sheet are important for modeling magnetotail motion/evolution and charged particle energization. Because of the magnetotail current sheet's dynamical nature, however, simultaneous plasma and magnetic field measurements at different radial distances are required to reveal this configuration. Simultaneous observations of the magnetotail current sheet from Time History of Events and Macroscale Interactions during Substorms (THEMIS) D (around 10RE downtail), Geotail (around 30RE downtail), and Acceleration, Reconnection, Turbulence and Electrodynamics of the Moons Interaction with the Sun (ARTEMIS) P1 (around 55RE downtail) are used to study distributions of plasma (ion) density and temperature along (Earth-Sun direction) and across (north-south direction) the magnetotail. Fourteen events (each including several current sheet crossings at different downtail distances) are studied. We demonstrate that the plasma temperature along and across the magnetotail varies more significantly than plasma density does. The temperature decrease from equatorial plane to current sheet boundaries is a major contributor to the cross-tail pressure balance. The Alfven velocity VA,B calculated at the current sheet boundaries increases significantly toward the Earth from 700 km/s at lunar orbit ˜55RE to 2200 km/s around ˜10RE downtail. The corresponding energy EA=mpVA,B2 (mp is the proton mass) is 4 times larger than the plasma temperature T0 in the magnetotail's equatorial plane, whereas the ratio EA/T0 is constant along the magnetotail. The plasma temperature T0 measured around lunar orbit in the magnetotail agrees well with the simultaneously measured energy of solar wind protons mpVSW2/2 (VSW is the solar wind speed).

  1. Development of an x-ray Talbot-Lau moire deflectometer for fast density profile measurements of dense plasmas generated by beam-target interactions

    Energy Technology Data Exchange (ETDEWEB)

    Clayton, Dan [National Security Technol., LLC, Los Alamos, NM (United States); Berninger, M; Meidinger, A; Stutman, Dan; Valdivia, Maria Pia

    2015-05-01

    For the first time an x-ray Talbot-Lau moire deflectometer is being developed that will use a flash tube source and fast detector for dynamic density gradient measurements. In Talbot-Lau moire deflectometry, an x-ray grating makes an image of itself on a second grating (the Talbot effect) to produce a moire pattern on a detector. The test object is placed between these gratings, with variations in index of refraction changing the pattern. A third grating in front of an incoherent x-ray source produces an array of coherent sources. With a 150 kV x-ray flash tube as the source, the gratings are placed in a glancing angle setup for performance at ~60 keV. The detector is a gated CCD with a fast scintillator for x-ray conversion. This diagnostic, designed for the Dual-Axis Radiographic Hydrodynamic Test facility (DARHT) at Los Alamos National Laboratory, measures the density profile of dense plasma plumes ejected from beam-target interactions. DARHT has two high-current, pulsed, inductive linear electron accelerators with bremsstrahlung targets at the end of each beam line to create 2-D radiographic images of hydrodynamic tests. One multi-pulse accelerator has up to four beam pulses striking the same target within 2 μs. Computer simulations that model target evolution and ejected material between pulses are used to design these targets for optimal radiographic performance; the x-ray deflectometer will directly measure density gradients in the ejected plumes and provide the first experimental constraints to these models. During the first year, currently underway, the diagnostic systems are being designed. In year two, the flash tube and fast detector will be deployed at DARHT for radiographic imaging while the deflectometer is built and tested on the bench with a continuous source. Finally, in year three, the fast deflectometer will be installed on DARHT and density measurements will be performed.

  2. The accretion history of dark matter halos II: The connections with the mass power spectrum and the density profile

    CERN Document Server

    Correa, Camila A; Schaye, Joop; Duffy, Alan R

    2015-01-01

    We explore the relation between the structure and mass accretion histories of dark matter halos using a suite of cosmological simulations. We confirm that the formation time, defined as the time when the virial mass of the main progenitor equals the mass enclosed within the scale radius, correlates strongly with concentration. We provide a semi-analytic model for halo mass history that combines analytic relations with fits to simulations. This model has the functional form, $M(z) = M_{0}(1+z)^{\\alpha}e^{\\beta z}$, where the parameters $\\alpha$ and $\\beta$ are directly correlated with concentration. We then combine this model for the halo mass history with the analytic relations between $\\alpha$, $\\beta$ and the linear power spectrum derived by Correa et al. (2014) to establish the physical link between halo concentration and the initial density perturbation field. Finally, we provide fitting formulas for the halo mass history as well as numerical routines, we derive the accretion rate as a function of halo ma...

  3. Obtención de modelo matemático para el desarrollo del perfil del ala de una aeronave. // Obtaining a mathematical model for the development of the profile of the airship wing.

    Directory of Open Access Journals (Sweden)

    R. Cabrera Pedroso

    2008-05-01

    Full Text Available El presente trabajo está dirigido a brindar un modelo matemático que permita el cálculo y determinación de una funciónanalítica para la obtención del perfil de un ala de geometría simétrica y variable de una aeronave con el empleo de métodoscomputacionales. En el artículo se analiza los métodos para la elaboración de sistemas de cálculo basados en modelosmatemáticos obtenidos en MATLAB 7.0 e implementados con el software LabVIEW 6.0 a través de programas de diseñosasistidos por computadoras en AUTOCAD (AUTOLISP. Los diferentes tópicos abordados dan a los interesados una ideaglobal del desarrollo de esta tecnología computacional y su aplicación a ramas de la mecánica, así como la metodologíaseguida para obtener el perfil aerodinámico de un ala. También se exponen aspectos generales del empleo de la funciónAUTOLISP y el código fuente del programa diseñado.Palabras claves: perfil de alas, modelos matemáticos, AutoCAD, AutoLISP, medición experimental.__________________________________________________________________________Abstract.This article was carried out to obtain a mathematical model that allows the calculation and determination of an analyticfunction of symmetrical geometry profile and variable. In the article it is analyzed the methods for the elaboration ofsystem of calculations based on mathematical models obtained with the software language LabVIEW 6.0 and it is used todeveloping the program attended by the computers AUTOCAD (AUTOLISP. The approached topics give to the interestedparties a global idea of the development it gives this technology and their application to branches of the mechanicalspecialties, as well as the followed methodology to obtain the aerofoil profile of a wing. General aspects are also exposedof the employment of the function AUTOLISP and the source code on the sketch program.Key words: Wing profiles, mathematical models, AutoCAD, AutoLISP, experimental measurement.

  4. High-throughput immuno-profiling of mamba (Dendroaspis) venom toxin epitopes using high-density peptide microarrays

    DEFF Research Database (Denmark)

    Engmark, Mikael; Andersen, Mikael Rørdam; Laustsen, Andreas Hougaard

    2016-01-01

    Snakebite envenoming is a serious condition requiring medical attention and administration of antivenom. Current antivenoms are antibody preparations obtained from the plasma of animals immunised with whole venom(s) and contain antibodies against snake venom toxins, but also against other antigens....... In order to better understand the molecular interactions between antivenom antibodies and epitopes on snake venom toxins, a high-throughput immuno-profiling study on all manually curated toxins from Dendroaspis species and selected African Naja species was performed based on custom-made high...

  5. What is the impact of obtaining medical clearance to participate in a randomised controlled trial examining a physical activity intervention on the socio-demographic and risk factor profiles of included participants?

    Science.gov (United States)

    Duncan, Mitch J; Rosenkranz, Richard R; Vandelanotte, Corneel; Caperchione, Cristina M; Rebar, Amanda L; Maeder, Anthony J; Tague, Rhys; Savage, Trevor N; van Itallie, Anetta; Mummery, W Kerry; Kolt, Gregory S

    2016-12-07

    Requiring individuals to obtain medical clearance to exercise prior to participation in physical activity interventions is common. The impact this has on the socio-demographic characteristic profiles of participants who end up participating in the intervention is not clear. As part of the multi-component eligibility screening for inclusion in a three-arm randomised controlled trial examining the efficacy of a web-based physical activity intervention, individuals interested in participating were required to complete the Physical Activity Readiness Questionnaire (PAR-Q). The PAR-Q identified individuals as having lower or higher risk. Higher-risk individuals were required to obtain medical exercise clearance prior to enrolment. Comparisons of the socio-demographic characteristics of the lower- and higher-risk individuals were performed using t tests and chi-square tests (p = 0.05). A total of 1244 individuals expressed interest in participating, and 432 were enrolled without needing to undergo further screening. Of the 251 individuals required to obtain medical clearance, 148 received clearance, 15 did not receive clearance and 88 did not return any form of clearance. A total of 105 individuals were enrolled after obtaining clearance, and the most frequent reason for being required to seek clearance was for using blood pressure/heart condition medication. Higher-risk individuals were significantly older, had a higher body mass index and engaged in more sedentary behaviour than lower-risk individuals. Use of more inclusive participant screening protocols that maintain high levels of participant safety are encouraged. Allowing individuals to obtain medical clearance to participate can result in including a more diverse population likely to benefit most from participation. Australian New Zealand Clinical Trials Registry ( ACTRN12611000157976 ). Registered on 9 February 2011.

  6. Modelling of the electron density profile in the lowest part of ionosphere D-region on the basis of radiowave absorption data. 1. Theoretical model.

    Science.gov (United States)

    Mukhtarov, P.; Pancheva, D.

    1996-11-01

    A simplified full-wave method adapted to the propagation of very obliquely incident LF radio waves is developed. For a selected ionosphere model the wave-field structure is calculated inside a horizontally stratified ionosphere and the peculiarities of the reflected field are clearly described. The penetration of the investigated radio waves in the lower ionosphere at noon-time is found to be restricted to a layer several wavelengths thick. The reflected wave is created entirely by the mechanism of partial reflections and the region responsible for its formation is usually below 70 km. The influence of some typical parameters of the electron density profile, as well as the atmospheric pressure and temperature, on the attenuation of the investigated radio waves is demonstrated. It is also found that the reflection at very oblique incidence depends mainly on the height of the bottom of the ionosphere.

  7. High-density PhyloChip profiling of stimulated aquifer microbial communities reveals a complex response to acetate amendment

    Energy Technology Data Exchange (ETDEWEB)

    Handley, Kim M.; Wrighton, Kelly E.; Piceno, Y. M.; Anderson, Gary L.; DeSantis, Todd; Williams, Kenneth H.; Wilkins, Michael J.; N' Guessan, A. L.; Peacock, Aaron; Bargar, John R.; Long, Philip E.; Banfield, Jillian F.

    2012-06-13

    There is increasing interest in harnessing the functional diversity of indigenous microbial communities to transform and remediate a wide range of environmental contaminants. Understanding the response of communities to stimulation, including flanking taxa, presents important opportunities for optimizing remediation approaches. We used high-density PhyloChip microarray analysis to comprehensively determine community membership and abundance patterns amongst a suite of samples from U(VI) bioremediation experiments. Samples were unstimulated or collected during Fe(III) and sulfate reduction from an acetate-augmented aquifer in Rifle, Colorado, and from laboratory experiments using field-collected materials. Results showed the greatest diversity in abundant SRB lineages was present in naturally-reduced sediment. Desulfuromonadales and Desulfobacterales were consistently identified as the dominant Fe(III)- and sulfate-reducing bacteria (IRB and SRB) throughout acetate amendment experiments. Stimulated communities also exhibited a high degree of functional redundancy amongst enriched flanking members. Not surprisingly, competition for both sulfate and iron was evident amongst abundant taxa, but the distribution and abundance of these ancillary SRB (Peptococcaceae, Desulfovibrionales and Syntrophobacterales), and lineages containing IRB (excluding Desulfobacteraceae) was heterogeneous amongst sample types. Interesting, amongst the most abundant taxa, particularly during sulfate reduction, were Epsilonproteobacteria that perform microaerobic or nitrate-dependant sulfur oxidation, and a number of bacteria other than Geobacteraceae that may enzymatically reduce U(VI). Finally, in depth community probing with PhyloChip determined the efficacy of experimental approaches, notably revealing striking similarity amongst stimulated sediment (from drill cores and in-situ columns) and groundwater communities, and demonstrating that sediment-packed in-situ (down-well) columns served

  8. Self-focusing of a Hermite-cosh Gaussian laser beam in a magnetoplasma with ramp density profile

    Energy Technology Data Exchange (ETDEWEB)

    Nanda, Vikas; Kant, Niti; Wani, Manzoor Ahmad [Department of Physics, Lovely Professional University, Phagwara 144411, Punjab (India)

    2013-11-15

    The early and strong self-focusing of a Hermite-cosh-Gaussian laser beam in magnetoplasma in the presence of density ramp has been observed. Focusing and de-focusing nature of the Hermite-cosh-Gaussian laser beam with decentered parameter and magnetic field has been studied, and strong self-focusing is reported. It is investigated that decentered parameter 'b' plays a significant role for the self-focusing of the laser beam and is very sensitive as in case of extraordinary mode. For mode indices, m = 0, 1, 2, and b = 4.00, 3.14, and 2.05, strong self-focusing is observed. Similarly in case of ordinary mode, for m = 0, 1, 2 and b = 4.00, 3.14, 2.049, respectively, strong self-focusing is reported. Further, it is seen that extraordinary mode is more prominent toward self-focusing rather than ordinary mode of propagation. For mode indices m = 0, 1, and 2, diffraction term becomes more dominant over nonlinear term for decentered parameter b=0. For selective higher values of decentered parameter in case of mode indices m=0, 1, and 2, self-focusing effect becomes strong for extraordinary mode. Also increase in the value of magnetic field enhances the self-focusing ability of the laser beam, which is very useful in the applications like the generation of inertial fusion energy driven by lasers, laser driven accelerators, and x-ray lasers.

  9. Analysis of the diagnostic presentation profile, parathyroidectomy indication and bone mineral density follow-up of Brazilian patients with primary hyperparathyroidism

    Directory of Open Access Journals (Sweden)

    U.E.M. Oliveira

    2007-04-01

    Full Text Available Primary hyperparathyroidism is an endocrine disorder with variable clinical expression, frequently presenting as asymptomatic hypercalcemia in Western countries but still predominantly as a symptomatic disease in developing countries. The objective of this retrospective study was to describe the diagnostic presentation profile, parathyroidectomy indication and post-surgical bone mineral density follow-up of patients with primary hyperparathyroidism seen at a university hospital. We found 115 patients (92 women, median age 56 years with primary hyperparathyroidism diagnosed during the last 20 years. We defined symptomatic patients based on the presence of any classical symptom affecting bone, kidney or the neuromuscular system. Surgical criteria followed the guidelines of the National Institutes of Health regarding asymptomatic primary hyperparathyroidism. Symptomatic patients and patients meeting surgical criteria for parathyroidectomy were 66 and 93% of the sample, respectively. Median calcium and parathyroid hormone values were 11.9 mg/dL and 189 pg/mL, respectively. After surgical treatment, 97% of patients were cured, with increases in bone mineral density of 19.4% in the lumbar spine and 15.7% in the femoral neck 3 years after surgery. Greater bone mass increases were detected in pre-menopausal women, men, and in symptomatic and younger patients, both in the lumbar spine and femoral neck. Our results support the previous findings of a predominantly symptomatic disease with a presentation profile that could be mainly related to a delayed diagnosis. Nevertheless, genetic and racial backgrounds, and nutritional factors such as calcium and vitamin D deficiency may play a role in the clinical presentation of primary hyperparathyroidism of Brazilian patients.

  10. The SL2S Galaxy-scale Lens Sample. IV. The dependence of the total mass density profile of early-type galaxies on redshift, stellar mass, and size

    CERN Document Server

    Sonnenfeld, Alessandro; Gavazzi, Raphaël; Suyu, Sherry H; Marshall, Philip J; Auger, Matthew W; Nipoti, Carlo

    2013-01-01

    We present optical and near infrared spectroscopy obtained at Keck, VLT, and Gemini for a sample of 36 secure strong gravitational lens systems and 17 candidates identified as part of the SL2S survey. The deflectors are massive early-type galaxies in the redshift range z_d=0.2-0.8, while the lensed sources are at z_s=1-3.5. We combine this data with photometric and lensing measurements presented in the companion paper III and with lenses from the SLACS and LSD surveys to investigate the cosmic evolution of the internal structure of massive early-type galaxies over half the age of the universe. We study the dependence of the slope of the total mass density profile \\gamma' (\\rho(r)\\propto r^{-\\gamma'}) on stellar mass, size, and redshift. We find that two parameters are sufficent to determine \\gamma' with less than 6% residual scatter. At fixed redshift, \\gamma' depends solely on the surface stellar mass density \\partial \\gamma'/ \\partial \\Sigma_*=0.38\\pm 0.07, i.e. galaxies with denser stars also have steeper ...

  11. Spatial profiles of electron density, electron temperature, average ionic charge, and EUV emission of laser-produced Sn plasmas for EUV lithography

    Science.gov (United States)

    Sato, Yuta; Tomita, Kentaro; Tsukiyama, Syoichi; Eguchi, Toshiaki; Uchino, Kiichiro; Kouge, Kouichiro; Tomuro, Hiroaki; Yanagida, Tatsuya; Wada, Yasunori; Kunishima, Masahito; Kodama, Takeshi; Mizoguchi, Hakaru

    2017-03-01

    Spatial profiles of the electron density (n e), electron temperature (T e), and average ionic charge (Z) of laser-produced Sn plasmas for EUV lithography, whose conversion efficiency (CE) is sufficiently high for practical use, were measured using a collective Thomson scattering (TS) technique. For plasma production, Sn droplets of 26 µm diameter were used as a fuel. First, a picosecond-pulsed laser was used to expand a Sn target. Next, a CO2 laser was used to generate plasmas. By changing the injection timing of the picosecond and CO2 lasers, three different types of plasmas were generated. The CEs of the three types of plasmas differed, and ranged from 2.8 to 4.0%. Regarding the different plasma conditions, the spatial profiles of n e, T e, and Z clearly differed. However, under all plasma conditions, intense EUV was only observed at a sufficiently high T e (> 25 eV) and in an adequate n e range [1024–(2 × 1025) m‑3]. These plasma parameters lie in the efficient-EUV light source range, as predicted by simulations.

  12. Effect of current density and pH in obtaining the Ni-Fe alloy by electrodeposition; Efeito da densidade de corrente e pH na obtencao da liga Ni-Fe por eletrodeposicao

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Jose Anderson Machado; Raulino, Anamelia de Medeiros Dantas; Raulino, Jose Leonardo Costa; Campos, Ana Regina Nascimento; Prasad, Shiva; Santana, Renato Alexandre Costa de, E-mail: jmo.anderson@gmail.com, E-mail: anameliadantas@yahoo.com.br, E-mail: leonardo.jcr@hotmail.com, E-mail: arncampos@yahoo.com.br, E-mail: prasad@deq.ufcg.edu.br, E-mail: renatoacs@ufcg.edu.br [Universidade Federal de Campina Grande (UFCG), Cuite, PB (Brazil). Lab. de Eletroquimica e Corrosao

    2017-01-15

    Metallic coatings can be applied for different purposes, for example to improve the mechanical, catalytic, anti corrosive properties or simply to improve the decorative appearance. In the work the Fe-Ni alloys have been obtained by electrodeposition process using a simple electrolytic bath containing the reagents, nickel sulfate, iron sulfate and sodium tartrate. A complete experimental design 2{sup 2} , associated with the response surface methodology (RSM) technique was used as optimization tool. Chemical composition, current efficiency, surface morphology and electrochemical corrosion measures were performed. It was observed that a decrease in the pH favored an increase in iron and decrease in nickel contents in the alloy. The iron content influenced the alloy morphology. The best experiment showed an average corrosion resistance 5471.5 Ω.cm² and a corrosion current density 4.814x10{sup -6} A/cm². This experiment presented a composition of 70 wt% Ni and 30 wt% Fe in the alloy and an average deposition current efficiency of 58.7%. (author)

  13. Lipid, fatty acid and energy density profiles of white sharks: insights into the feeding ecology and ecophysiology of a complex top predator.

    Science.gov (United States)

    Pethybridge, Heidi R; Parrish, Christopher C; Bruce, Barry D; Young, Jock W; Nichols, Peter D

    2014-01-01

    Lipids are major sources of metabolic energy in sharks and are closely linked to environmental conditions and biological cycles, such as those related to diet, reproduction and migration. In this study, we report for the first time, the total lipid content, lipid class composition and fatty acid profiles of muscle and liver tissue of white sharks, Carcharodon carcharias, of various lengths (1.5-3.9 m), sampled at two geographically separate areas off southern and eastern Australia. Muscle tissue was low in total lipid content (90% of total lipid) and polyunsaturated fatty acids (34±12% of total fatty acids). In contrast, liver was high in total lipid which varied between 51-81% wm and was dominated by triacylglycerols (>93%) and monounsaturated fatty acids (36±12%). With knowledge of total lipid and dry tissue mass, we estimated the energy density of muscle (18.4±0.1 kJ g-1 dm) and liver (34.1±3.2 kJ g-1 dm), demonstrating that white sharks have very high energetic requirements. High among-individual variation in these biochemical parameters and related trophic markers were observed, but were not related to any one biological or environmental factor. Signature fatty acid profiles suggest that white sharks over the size range examined are generalist predators with fish, elasmobranchs and mammalian blubber all contributing to the diet. The ecological applications and physiological influences of lipids in white sharks are discussed along with recommendations for future research, including the use of non-lethal sampling to examine the nutritional condition, energetics and dietary relationships among and between individuals. Such knowledge is fundamental to better understand the implications of environmental perturbations on this iconic and threatened species.

  14. Radially extended kinematics and stellar populations of the massive ellipticals NGC1600, NGC4125 and NGC7619. Constraints on the outer dark halo density profile

    CERN Document Server

    Pu, S B; Fabricius, M H; Thomas, J; Bender, R; Han, Z

    2010-01-01

    We present high quality long slit spectra along the major and minor axes out to 1.5-2 Re (14-22 kpc) of three bright elliptical galaxies (NGC1600, NGC4125, NGC7619) obtained at the Hobby-Eberly Telescope (HET). We derive stellar kinematic profiles and Lick/IDS indices (Hbeta, Mgb, Fe5015, Fe5270, Fe5335, Fe5406). Moreover, for NGC4125 we derive gas kinematics and emission line strengths. We model the absorption line strengths using Simple Stellar Populations models that take into account the variation of [\\alpha/Fe] and derive ages, total metallicity and element abundances. Overall, we find that the three galaxies have old and [\\alpha/Fe] overabundant stellar populations with no significant gradients. The metallicity is supersolar at the center with a strong negative radial gradient. For NGC4125, several pieces of evidence point to a recent dissipational merger event. We calculate the broad band color profiles with the help of SSP models. All of the colors show sharp peaks at the center of the galaxies, mainl...

  15. A rumble in the dark: signatures of self-interacting dark matter in supermassive black hole dynamics and galaxy density profiles

    Science.gov (United States)

    Di Cintio, Arianna; Tremmel, Michael; Governato, Fabio; Pontzen, Andrew; Zavala, Jesús; Bastidas Fry, Alexander; Brooks, Alyson; Vogelsberger, Mark

    2017-08-01

    We explore for the first time the effect of self-interacting dark matter (SIDM) on the dark matter (DM) and baryonic distribution in massive galaxies formed in hydrodynamical cosmological simulations, including explicit baryonic physics treatment. A novel implementation of supermassive black hole (SMBH) formation and evolution is used, as in Tremmel et al., allowing us to explicitly follow the SMBH dynamics at the centre of galaxies. A high SIDM constant cross-section is chosen, σ = 10 cm2gr-1, to amplify differences from CDM models. Milky Way-like galaxies form a shallower DM density profile in SIDM than they do in cold dark matter (CDM), with differences already at 20 kpc scales. This demonstrates that even for the most massive spirals, the effect of SIDM dominates over the adiabatic contraction due to baryons. Strikingly, the dynamics of SMBHs differs in the SIDM and reference CDM case. SMBHs in massive spirals have sunk to the centre of their host galaxy in both the SIDM and CDM run, while in less massive galaxies about 80 per cent of the SMBH population is off-centred in the SIDM case, as opposed to the CDM case in which ∼ 90 per cent of SMBHs have reached their host's centre. SMBHs are found as far as ∼9 kpc away from the centre of their host SIDM galaxy. This difference is due to the increased dynamical friction time-scale caused by the lower DM density in SIDM galaxies compared to CDM, resulting in core stalling. This pilot work highlights the importance of simulating in a full hydrodynamical context different DM models combined to the SMBH physics to study their influence on galaxy formation.

  16. Dose profile for electron beams obtained with CaSO{sub 4}:Ce,Eu thermoluminescent dosimeters; Perfil de dose de feixes de eletrons obtidos com dosimetros termoluminescentes de CaSO{sub 4}:Ce,Eu

    Energy Technology Data Exchange (ETDEWEB)

    Nunes, Maira G.; Rodrigues, Leticia L.C., E-mail: mgnunes@ipen.br [Instituto de Pesquisas Energerticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2012-12-15

    The calcium sulphate activated with cerium and europium (CaSO{sub 4}:Ce,Eu) thermoluminescent dosimeters (TLD) recently developed at Nuclear and Energy Research Institute as well as the calcium sulphate activated with dysprosium (CaSO{sub 4}: Dy) and lithium fluoride activated with magnesium and titanium, (LiF:Mg,Ti; TLD-100) TLDs, with long term applications in dosimetry and considered as standards, were used to obtain the dose profile for 3.43, 5.48, 8.27 and 11.67 MeV electron beams generated by a linear accelerator Clinac 2100-C (Varian) in the reference conditions defined by the TRS-398 code of practice. The routine dosimetry of the electron beams, performed with a calibrated ionization chamber, ensures that the electron beams fulfill the requirements of flatness and symmetry established in this code of practice. Thus, as the TRS-398 Code of Practice requirements are fulfilled by the measurements performed with the new TLD type, CaSO{sub 4}:Ce,Eu may be applied in clinical dosimetry of high energy electron beams. (author)

  17. Scattering Density Profile Model of POPG Bilayers as Determined by Molecular Dynamics Simulations and Small-Angle Neutron and X-ray Scattering Experiments

    Energy Technology Data Exchange (ETDEWEB)

    Kucerka, Norbert [Canadian Neutron Beam Centre and Comelius University (Slovakia); Holland, B [University of Guelph; Gray, C.G [University of Guelph; Tomberli, B [Brandon University; Katsaras, John [ORNL

    2012-01-01

    We combine molecular dynamics (MD) simulations and experiment, both small-angle neutron (SANS) and small-angle X-ray scattering (SAXS), to determine the precise structure of bilayers composed of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol (POPG), a lipid commonly encountered in bacterial membranes. Experiment and simulation are used to develop a one-dimensional scattering density profile (SDP) model suitable for the analysis of experimental data. The joint refinement of such data (i.e., SANS and SAXS) results in the area per lipid that is then used in the fixed-area simulations. In the final step, the direct comparison of simulated-to-experimental data gives rise to the detailed structure of POPG bilayers. From these studies we conclude that POPG s molecular area is 66.0 +/- 1.3 ^2, its overall bilayer thickness is 36.7 +/- 0.7 , and its hydrocarbon region thickness is 27.9 ( 0.6 , assuming a simulated value of 1203 ^3 for the total lipid volume.

  18. A direct dynamical measurement of the Milky Way's disk surface density profile, disk scale length, and dark matter profile at 4 kpc ≲ R ≲ 9 kpc

    Energy Technology Data Exchange (ETDEWEB)

    Bovy, Jo [Institute for Advanced Study, Einstein Drive, Princeton, NJ 08540 (United States); Rix, Hans-Walter, E-mail: bovy@ias.edu [Max-Planck-Institut für Astronomie, Königstuhl 17, D-69117 Heidelberg (Germany)

    2013-12-20

    We present and apply rigorous dynamical modeling with which we infer unprecedented constraints on the stellar and dark matter mass distribution within our Milky Way (MW), based on large sets of phase-space data on individual stars. Specifically, we model the dynamics of 16,269 G-type dwarfs from SEGUE, which sample 5 kpc < R{sub GC} < 12 kpc and 0.3 kpc ≲ |Z| ≲ 3 kpc. We independently fit a parameterized MW potential and a three-integral, action-based distribution function (DF) to the phase-space data of 43 separate abundance-selected sub-populations (MAPs), accounting for the complex selection effects affecting the data. We robustly measure the total surface density within 1.1 kpc of the mid-plane to 5% over 4.5 kpc < R{sub GC} < 9 kpc. Using metal-poor MAPs with small radial scale lengths as dynamical tracers probes 4.5 kpc ≲ R{sub GC} ≲ 7 kpc, while MAPs with longer radial scale lengths sample 7 kpc ≲ R{sub GC} ≲ 9 kpc. We measure the mass-weighted Galactic disk scale length to be R{sub d} = 2.15 ± 0.14 kpc, in agreement with the photometrically inferred spatial distribution of stellar mass. We thereby measure dynamically the mass of the Galactic stellar disk to unprecedented accuracy: M {sub *} = 4.6 ± 0.3 + 3.0 (R {sub 0}/ kpc – 8) × 10{sup 10} M {sub ☉} and a total local surface density of Σ{sub R{sub 0}}(Z=1.1 kpc)=68 ± 4 M{sub ⊙} pc{sup −2} of which 38 ± 4 M {sub ☉} pc{sup –2} is contributed by stars and stellar remnants. By combining our surface density measurements with the terminal velocity curve, we find that the MW's disk is maximal in the sense that V {sub c,} {sub disk}/V {sub c,} {sub total} = 0.83 ± 0.04 at R = 2.2 R{sub d} . We also constrain for the first time the radial profile of the dark halo at such small Galactocentric radii, finding that ρ{sub DM}(r; ≈R {sub 0})∝1/r {sup α} with α < 1.53 at 95% confidence. Our results show that action-based DF modeling of complex stellar data sets is now a feasible

  19. Magnetic momentum density, Fermi surface, and directional magnetic Compton profiles in LaSr2Mn2O7 and La1.2Sr1.8Mn2O7

    Science.gov (United States)

    Mijnarends, P. E.; Kaprzyk, S.; Barbiellini, B.; Li, Yinwan; Mitchell, J. F.; Montano, P. A.; Bansil, A.

    2007-01-01

    We have carried out first principles, all-electron computations of the magnetic momentum density ρmag(p) and magnetic Compton profiles (MCPs) for momentum transfer along the [100], [001], and [110] directions in LaSr2Mn2O7 and La1.2Sr1.8Mn2O7 within the local spin density approximation (LSDA) based band theory framework. Parallel measurements of these three MCPs from a single crystal of La1.2Sr1.8Mn2O7 at 5K in a magnetic field of 7T are also reported. ρmag(p) is shown to contain distinct peaks arising from the occupied majority-spin t2g electrons and to display images of the Fermi surface (FS) in the first and higher Brillouin zones (BZs). The overall shape of the MCPs, Jmag(pz) , obtained by integrating ρmag(p) over px and py , is found to be dominated by the majority-spin t2g states. The FS-related fine structure in the MCPs is, however, substantial only in the [100] MCP, which contains features arising from the large majority-spin hole sheets. The overall shapes and widths of the experimental MCPs along all three directions investigated are in reasonably good accord with theoretical predictions, although some discrepancies indicating inadequacy of the LSDA in treating the magnetic states can be identified. We discuss details of the FS-related signatures in the first and higher BZs in the [100] MCP and show that high resolution magnetic Compton scattering experiments with a momentum resolution of 0.1a.u. full-width-at-half-maximum or better will be necessary to observe this fine structure. We comment also on the feasibility of using positron annihilation spectroscopy in this connection.

  20. Programs to obtain vertical heights from mean sea level and for computing volume of sand/mineral along beaches:A case study with Kalbadevi beach profiling data and results.

    Digital Repository Service at National Institute of Oceanography (India)

    Ganesan, P.

    profile studies with collection of field data. The main purpose for undertaking this study was to compare the beach profiles done at different periods, using the newly developed programs in GWBASIC language. The benchmark pillars were established...: --------------------------------------------------------------------------------------------------------------------- Bench mark Position in Position in Remarks Pillar No WGS-1984 Indian -1975 Latitude (N) Longitude (E) Latitude (N) Longitude (E) BP - 1...

  1. Estudo da densidade de ligações Cruzadas em géis superabsorventes obtidos do acetato de celulose Study of the crosslinking density in superabsorbent gels obtained from cellulose acetate

    Directory of Open Access Journals (Sweden)

    André M. Senna

    2013-01-01

    :3] and [3:1] PMDA mol/mol of free OH, respectively. A gel was synthesized in excess of 200% of PMDA in relation to free OH groups of the AC. The basis of the Flory-Rehner theory was used for determining crosslinking in the gels. Briefly, the main results showed that the crosslinking density increased proportionally to the amount of PMDA added to the reaction medium. Distinct AFM topographies were obtained for distinct gels, which were also different from the polymer cellulose acetate. This work was motivated by the technological importance of polymers from renewable sources such as cellulose, in which a cellulose derivative was developed with promising application in drug delivery and in adsorption of heavy metals in aqueous systems. The advantage of this cellulose acetate derivative is the use of fewer steps in its synthesis.

  2. Association between the biochemical profiles in blood and bone mineral density in Chinese Han population: findings from a cross-sectional study

    Directory of Open Access Journals (Sweden)

    Chen HX

    2016-11-01

    Full Text Available Hong-Xia Chen,1,2,* Li-Bing Wu,3,* Zhong-Ji Meng1 1Institute of Biomedicine, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei Province, People’s Republic of China; 2Department of Environmental, Agricultural, & Occupational Health, College of Public Health, University of Nebraska Medical Center, Omaha, NE, USA; 3Department of Nuclear Medicine, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei Province, People’s Republic of China *These authors contributed equally to this work. Abstract: This study investigated the possible correlation between blood biochemical profiles and bone mineral density (BMD in the Chinese Han population. We conducted a cross-sectional analysis using participants randomly selected from the Health Screening Center of Taihe Hospital, Hubei University of Medicine, which included a total of 285 individuals, varied in ages from 31 years to 63 years. The height, weight, and body mass index (BMI of each subject were measured, as well as fasting blood glucose (FBG, triglycerides, total cholesterol, blood uric acid (UA, blood urea nitrogen, and blood creatinine. We evaluated BMD at the wrist (grams per centimeter square using a dual-energy X-ray absorptiometry scan. The mean ages of female and male groups were 45.32±8.24 years and 46.76±9.01 years, respectively. The mean age of the study population was 46.14±8.79 years, which is similar to the general population. The mean BMI values were 22.08±2.38 kg/m2 and 24.50±2.67 kg/m2 in the female and male population, respectively, representing a statistically significant difference (P<0.05. No significant differences in levels of FBG total cholesterol, or triglycerides were seen among the male and female population. Multiple linear regression analysis was performed using BMD as outcome variables and BMI, blood UA, FBG, total cholesterol, triglycerides, urea nitrogen, and blood creatinine as covariates, and the regression equation was established as Y=0

  3. Comparison of the fluid dynamic models of solids density profile in a FCC cold riser with aid of gamma-ray transmission

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Valdemir A. dos, E-mail: valdemir.alexandre@pq.cnpq.b [Universidade Catolica de Pernambuco, Recife, PE (Brazil). Centro de Ciencia e Tecnologia; Dantas, Carlos C., E-mail: ccd@ufpe.b [Universidade Federal de Pernambuco (UFPE), Recife, PE (Brazil). Dept. de Energia Nuclear; Luna-Finkler, Christine L., E-mail: chrislluna@yahoo.com.b [Universidade Federal de Pernambuco (UFPE), Vitoria de Santo Antao, PE (Brazil). Centro Academico de Vitoria; Silva, Jose M.F., E-mail: jmfs5@yahoo.com.b [Universidade Federal de Pernambuco (UFPE), Recife, PE (Brazil). Dept. de Engenharia Quimica

    2009-07-01

    To measure the axial concentration of the solid component with aid of gamma radiation to compare two fluid dynamic models was the goal of this work. An {sup 241}Am radioactive source of a 9 7.4 centre dot10{sup 9} Bq intensity and the detector were collimated. A support of the arrangement allows dislocating source and detector in order to scan along of riser axial length. The gamma measurements are taken with a 0.05 m x 0.05 m NaI(Tl) detector associated to a mono and to a multichannel analyser which is provided by a Genie 2000, Canberra software for spectrum evaluation. By integrating the 0.060 MeV photopeak of the {sup 241}Am gamma spectrum all the attenuation measurements are taken. The catalyst mass absorption coefficient, mu =331 m{sup 2}/kg, was determined in a previous experiment. For the solid volumetric fraction about 0.02, in the solid entrance in riser, the fluid dynamic model performances were compared by four different search numeric methods (Quasi-Newton, Hook-Jeeves Pattern Mooves, Rosenbrock Pattern Search and Simplex Procedure) from user-specified regression (Custom loss function) from nonlinear estimation of SIMULINK/Matlab{sup R} and Statistica software. In this standard multiple regression type it estimates the regression coefficients by 'finding' those coefficients that minimize the residual variance (sum of squared residuals) around the regression line. Any deviation of an observed score from a predicted score signifies some loss in the accuracy of prediction. The comparison tests between experimental and simulated data showed that the Santana's model was more indicated to simulate the solid axial density profile in a cold flow riser of a FCC pilot unit. (author)

  4. Modeling of power spectral density of modified von Karman atmospheric phase turbulence and acousto-optic chaos using scattered intensity profiles over discrete time intervals

    Science.gov (United States)

    Chatterjee, Monish R.; Mohamed, Fathi H. A.

    2014-10-01

    In recent research, propagation of plane electromagnetic (EM) waves through a turbulent medium with modified von Karman phase characteristics was modeled and numerically simulated using transverse planar apertures representing narrow phase turbulence along the propagation path. The case for extended turbulence was also studied by repeating the planar phase screens multiple times over the propagation path and incorporating diffractive effects via a split-step algorithm. The goal of the research reported here is to examine two random phenomena: (a) atmospheric turbulence due to von Karman-type phase fluctuations, and (b) chaos generated in an acousto-optic (A-O) Bragg cell under hybrid feedback. The latter problem has been thoroughly examined for its nonlinear dynamics and applications in secure communications. However, the statistical characteristics (such as the power spectral density (PSD)) of the chaos have not been estimated in recent work. To that end, treating the chaos phenomena as a random process, the time waveforms of the chaos intensity and their spectra are numerically evaluated over a (large) number of time iterations. These spectra are then averaged to derive the equivalent PSD of the A-O chaos. For the turbulence problem, an optical beam passing through an input pinhole is propagated through a random phase screen (placed at different locations) to a desired distance (typically near-field) under different levels of turbulence strength. The resulting spatial intensity profile is then averaged and the process repeated over a (large) number of pre-specified time intervals. From this data, once again, the turbulence PSD is calculated via the Fourier spectra of the average intensity snapshots. The results for the two systems are compared.

  5. Pharmacologic profile of the Adnectin BMS-962476, a small protein biologic alternative to PCSK9 antibodies for low-density lipoprotein lowering.

    Science.gov (United States)

    Mitchell, Tracy; Chao, Ginger; Sitkoff, Doree; Lo, Fred; Monshizadegan, Hossain; Meyers, Daniel; Low, Simon; Russo, Katie; DiBella, Rose; Denhez, Fabienne; Gao, Mian; Myers, Joseph; Duke, Gerald; Witmer, Mark; Miao, Bowman; Ho, Siew P; Khan, Javed; Parker, Rex A

    2014-08-01

    Proprotein convertase subtilisin kexin-9 (PCSK9) is an important pharmacological target for decreasing low-density lipoprotein (LDL) in cardiovascular disease, although seemingly inaccessible to small molecule approaches. Compared with therapeutic IgG antibodies currently in development, targeting circulating PCSK9 with smaller molecular scaffolds could offer different profiles and reduced dose burdens. This inspired genesis of PCSK9-binding Adnectins, a protein family derived from human fibronectin-10th-type III-domain and engineered for high-affinity target binding. BMS-962476, an ∼11-kDa polypeptide conjugated to polyethylene glycol to enhance pharmacokinetics, binds with subnanomolar affinity to human. The X-ray cocrystal structure of PCSK9 with a progenitor Adnectin shows ∼910 Å(2) of PCSK9 surface covered next to the LDL receptor binding site, largely by residues of a single loop of the Adnectin. In hypercholesterolemic, overexpressing human PCSK9 transgenic mice, BMS-962476 rapidly lowered cholesterol and free PCSK9 levels. In genomic transgenic mice, BMS-962476 potently reduced free human PCSK9 (ED50 ∼0.01 mg/kg) followed by ∼2-fold increases in total PCSK9 before return to baseline. Treatment of cynomolgus monkeys with BMS-962476 rapidly suppressed free PCSK9 >99% and LDL-cholesterol ∼55% with subsequent 6-fold increase in total PCSK9, suggesting reduced clearance of circulating complex. Liver sterol response genes were consequently downregulated, following which LDL and total PCSK9 returned to baseline. These studies highlight the rapid dynamics of PCSK9 control over LDL and liver cholesterol metabolism and characterize BMS-962476 as a potent and efficacious PCSK9 inhibitor.

  6. Deduction of temp erature and density spatial profile for implosion core by multi-ob jective optimization%多目标优化推断内爆芯部温度和密度空间分布

    Institute of Scientific and Technical Information of China (English)

    董建军; 邓博; 曹柱荣; 江少恩

    2014-01-01

    The spatial profiles of implosion core temperature and density are very important to check the theoretical simulation codes and understand the implosion physics in depth. A method is presented that the temperature and density profiles are evaluated by multi-objective optimization, where the normalized intensity profile is calculated from implosion core X-ray images. Two models, i.e., the model with considering absorption and the model without considering absorption, are studied. The results indicate that the temperature profile from the model without considering absorption is about twice that from the model with considering absorption. The density profiles evaluated by the two models are almost the same in the fuel zone, but the density from the model without considering absorption is more than ten times smaller than that from the model with considering absorption in the ablator zone.%内爆芯部的温度和密度分布对理论模拟程序的校验以及深入理解内爆物理非常重要.本文提出了一种通过内爆芯部X光图像获得归一化的角向平均强度分布,并利用多目标优化算法推断芯部的温度和密度空间分布的方法.通过吸收模型和无吸收模型加以研究,结果表明无吸收模型推断的温度分布要比吸收模型高大约1倍;在芯部燃料区,两种模型推断的密度分布接近,在芯部边缘,无吸收模型的结果是吸收模型的1/10.

  7. Density measurements using coherence imaging spectroscopy based on Stark broadeninga)

    Science.gov (United States)

    Lischtschenko, O.; Bystrov, K.; De Temmerman, G.; Howard, J.; Jaspers, R. J. E.; König, R.

    2010-10-01

    A coherence imaging camera has been set up at Pilot-PSI. The system is to be used for imaging the plasma density through the Stark effect broadening of the Hγ line. Local density values are then obtained by the Abel inversion of the measured interferometric fringe contrast. This report will present the instrument setup and proof-of-principle demonstration. The inverted spatial electron density profiles obtained near the cascaded arc source of Pilot-PSI in discharges with axial magnetic field of B=0.4 T are compared with an independent measurement of electron density by Thomson scattering and good agreement is found.

  8. Density measurements using coherence imaging spectroscopy based on Stark broadening

    Energy Technology Data Exchange (ETDEWEB)

    Lischtschenko, O.; Bystrov, K.; De Temmerman, G. [Association EURATOM-FOM, FOM-Institute for Plasma Physics Rijnhuizen, partner in the Trilateral Euregio Cluster, P.O. Box 1207, 3430 BE Nieuwegein (Netherlands); Howard, J. [Research Laboratory, Australian National University, Canberra, Australian Capital Territory 0200 (Australia); Jaspers, R. J. E. [Fusion Group, Eindhoven University of Technology, Postbus 513, 5600 MB Eindhoven (Netherlands); Koenig, R. [EURATOM Association, Max-Planck-Institut fuer Plasmaphysik, TI Greifswald, Wendelsteinstr.1, D-17491 Greifswald (Germany)

    2010-10-15

    A coherence imaging camera has been set up at Pilot-PSI. The system is to be used for imaging the plasma density through the Stark effect broadening of the H{sub {gamma}} line. Local density values are then obtained by the Abel inversion of the measured interferometric fringe contrast. This report will present the instrument setup and proof-of-principle demonstration. The inverted spatial electron density profiles obtained near the cascaded arc source of Pilot-PSI in discharges with axial magnetic field of B=0.4 T are compared with an independent measurement of electron density by Thomson scattering and good agreement is found.

  9. 基于改进区间数密度集结算子指标群赋权方法%Research on Obtaining the Weights of Index Group Based on Modified Interval Number Density Aggregation Operator

    Institute of Scientific and Technical Information of China (English)

    贺芳

    2013-01-01

    A decision-making method with a modified interval number density aggregation operator is proposed to solve the group weights problems with index data known and weights unknown .First, the several concepts of in-terval number and interval number density aggregation operator are introduced , the method of interval number clustering is improved , the direct algorithm is applied to cluster the one-dimensional data , and fuzzy statistics variables are defined to make sure which is the best way to clustering .Then based on a modified interval number density aggregation operator the group weights problems with index data known and weights unknown are solved . Finally it is shown that the method is feasible and effective with an example .%针对指标数据已知,而权重数据未知的群组赋权问题,给出了一种基于改进的区间数密度集结算子来进行指标群组赋权的决策方法。首先给出了区间数和区间数密度集结算子( IDM)的定义及性质,改进了以前区间数聚类的方法,应用直接法对一维区间数据组进行聚类,并定义了模糊统计量,以确定最为合理的一种聚类方式。然后基于改进的区间数密度集结算子这种数学模型,来解决指标值数据已知,而权重未知的群组赋权问题。最后举例说明该方法的可行性和实用性。

  10. Correlation of the structural information obtained for europium-chelate ensembles from gas-phase photoluminescence and ion-mobility spectroscopy with density-functional computations and ligand-field theory.

    Science.gov (United States)

    Greisch, Jean-François; Chmela, Jiří; Harding, Michael E; Wunderlich, Dirk; Schäfer, Bernhard; Ruben, Mario; Klopper, Wim; Schooss, Detlef; Kappes, Manfred M

    2017-02-22

    We report a combined investigation of europium(iii)9-oxo-phenalen-1-one (PLN) coordination complexes, [Eu(PLN)4AE](+) with AE = Mg, Ca, and Sr, using gas-phase photoluminescence, trapped ion-mobility spectrometry and density-functional computations. In order to sort out the structural impact of the alkali earth dications on the photoluminescence spectra, the experimental data are compared to the predicted ligand-field splittings as well as to the collision cross-sections for different isomers of [Eu(PLN)4AE](+). The best fitting interpretation is that one isomer family predominantly contributes to the recorded luminescence. The present work demonstrates the complexity of the coordination patterns of